# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Swi5 PF07061.6 CAM59684.1 - 0.14 11.9 6.4 1.1 9.0 3.6 2.9 2 0 0 2 2 2 0 Swi5 DUF3522 PF12036.3 CAM59685.1 - 1.6e-61 207.3 11.5 1.9e-61 207.1 7.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) DUF2270 PF10028.4 CAM59685.1 - 0.3 10.5 1.7 0.82 9.1 0.1 2.0 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2270) DUF3522 PF12036.3 CAM59686.1 - 1.4e-57 194.5 3.0 1.4e-57 194.5 2.1 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3522) 7TMR-DISM_7TM PF07695.6 CAM59686.1 - 0.019 14.6 1.0 0.019 14.6 0.7 2.2 1 1 1 2 2 2 0 7TM diverse intracellular signalling DUF3382 PF11862.3 CAM59686.1 - 0.15 11.9 1.6 1.7 8.5 0.0 2.8 4 0 0 4 4 4 0 Domain of unknown function (DUF3382) DUF3671 PF12420.3 CAM59686.1 - 3.3 7.7 10.4 15 5.6 5.5 2.6 1 1 1 2 2 2 0 Protein of unknown function zf-RING_2 PF13639.1 CAM59687.1 - 2.1e-11 43.4 7.8 4.4e-11 42.4 5.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CAM59687.1 - 7.3e-09 35.5 6.9 1.4e-08 34.6 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CAM59687.1 - 6.7e-08 32.5 6.0 6.7e-08 32.5 4.1 2.3 2 2 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CAM59687.1 - 9.9e-08 31.5 6.7 1.9e-07 30.5 4.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CAM59687.1 - 1.4e-07 31.0 3.7 2.9e-07 30.0 2.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAM59687.1 - 8.9e-06 25.3 4.9 2e-05 24.1 3.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CAM59687.1 - 2.9e-05 23.8 6.4 6.7e-05 22.6 4.4 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 CAM59687.1 - 3.3e-05 23.6 1.4 3.3e-05 23.6 1.0 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 CAM59687.1 - 0.00015 21.3 6.9 0.00023 20.8 4.2 1.8 2 0 0 2 2 2 1 RING-type zinc-finger CpXC PF14353.1 CAM59687.1 - 0.0059 16.5 0.3 0.0059 16.5 0.2 1.6 2 0 0 2 2 2 1 CpXC protein zf-RING_6 PF14835.1 CAM59687.1 - 0.019 14.7 2.2 0.13 12.0 1.4 2.2 1 1 1 2 2 2 0 zf-RING of BARD1-type protein Myc-LZ PF02344.10 CAM59687.1 - 0.027 14.0 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 Myc leucine zipper domain zf-Nse PF11789.3 CAM59687.1 - 0.099 12.1 3.7 0.37 10.3 2.0 2.2 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.1 CAM59687.1 - 0.12 11.9 4.9 3.4 7.2 0.1 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 FANCL_C PF11793.3 CAM59687.1 - 0.13 12.2 7.2 1.3 9.0 2.3 2.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING-like PF08746.6 CAM59687.1 - 1.9 8.5 5.3 6 6.9 3.7 2.0 1 1 0 1 1 1 0 RING-like domain RINGv PF12906.2 CAM59687.1 - 2.9 8.0 7.7 0.91 9.6 2.8 2.1 2 1 0 2 2 2 0 RING-variant domain zf-Di19 PF05605.7 CAM59687.1 - 6.2 7.0 8.1 16 5.7 0.3 3.0 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DnaJ PF00226.26 CAM59688.1 - 9.4e-08 31.6 0.0 1.6e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain TilS_C PF11734.3 CAM59689.1 - 0.0029 16.7 0.0 0.0066 15.6 0.0 1.6 1 0 0 1 1 1 1 TilS substrate C-terminal domain DUF2606 PF10794.4 CAM59689.1 - 0.091 12.1 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) NAGidase PF07555.8 CAM59689.1 - 0.095 11.5 0.1 0.16 10.8 0.1 1.3 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase GCR1_C PF12550.3 CAM59689.1 - 0.32 10.8 3.2 0.26 11.2 0.8 1.9 2 0 0 2 2 2 0 Transcriptional activator of glycolytic enzymes Pkinase PF00069.20 CAM59690.1 - 4e-69 232.6 0.0 5.2e-69 232.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM59690.1 - 5.1e-41 140.4 0.0 7.5e-41 139.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_6 PF13516.1 CAM59690.1 - 2.2e-05 24.0 1.4 0.19 11.8 0.0 4.0 4 0 0 4 4 4 2 Leucine Rich repeat Kinase-like PF14531.1 CAM59690.1 - 6.9e-05 21.9 0.0 0.00011 21.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like LRR_4 PF12799.2 CAM59690.1 - 7.5e-05 22.2 0.1 0.00019 20.9 0.1 1.8 1 1 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CAM59690.1 - 0.0016 18.1 1.5 2.8 8.3 0.0 3.4 3 0 0 3 3 3 2 Leucine Rich Repeat RIO1 PF01163.17 CAM59690.1 - 0.0081 15.5 0.0 0.016 14.5 0.0 1.5 1 0 0 1 1 1 1 RIO1 family LRR_8 PF13855.1 CAM59690.1 - 0.072 12.8 0.4 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Leucine rich repeat APH PF01636.18 CAM59690.1 - 0.092 12.4 0.0 0.96 9.1 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Arf PF00025.16 CAM59691.1 - 8.9e-69 230.2 0.1 1.1e-68 229.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CAM59691.1 - 2.3e-11 43.2 0.0 2.7e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CAM59691.1 - 3.6e-10 39.1 0.3 6.3e-08 31.7 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CAM59691.1 - 2.2e-09 36.8 0.0 3e-09 36.3 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 CAM59691.1 - 2.7e-09 36.6 0.0 3.1e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAM59691.1 - 2.3e-07 31.3 0.0 3.4e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CAM59691.1 - 3.5e-06 26.9 0.0 5.2e-06 26.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CAM59691.1 - 0.022 14.0 0.9 0.14 11.4 0.6 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AP_endonuc_2 PF01261.19 CAM59691.1 - 0.088 12.0 0.0 0.27 10.4 0.0 1.7 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel GTP_EFTU PF00009.22 CAM59692.1 - 8.8e-54 181.7 0.0 1.5e-53 181.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CAM59692.1 - 5.7e-36 122.6 0.1 3.6e-35 120.0 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CAM59692.1 - 6.3e-18 64.6 0.4 6.3e-18 64.6 0.3 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CAM59692.1 - 1.8e-05 24.3 0.2 5.4e-05 22.7 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 CAM59692.1 - 4.1e-05 23.5 0.0 0.00014 21.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CAM59692.1 - 0.0035 16.5 0.1 0.018 14.2 0.0 2.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 CAM59692.1 - 0.0068 16.8 0.3 0.07 13.6 0.2 2.3 1 1 0 1 1 1 1 Miro-like protein Semialdhyde_dhC PF02774.13 CAM59692.1 - 0.019 14.8 0.1 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain Guanylate_cyc PF00211.15 CAM59703.1 - 4.2e-39 133.8 0.0 7.1e-39 133.0 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.15 CAM59704.1 - 6.5e-39 133.1 0.0 1.3e-38 132.2 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.15 CAM59705.2 - 1.1e-22 80.2 0.0 1.5e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.15 CAM59706.1 - 8.1e-38 129.6 0.0 1.3e-37 128.9 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Peripla_BP_6 PF13458.1 CAM59707.1 - 7.8e-08 32.0 3.2 1e-05 25.0 0.0 3.0 3 0 0 3 3 3 2 Periplasmic binding protein Kinesin PF00225.18 CAM59708.1 - 1.6e-40 138.8 0.0 5.6e-24 84.4 0.0 2.3 2 0 0 2 2 2 2 Kinesin motor domain WD40 PF00400.27 CAM59709.1 - 5.4e-35 118.0 16.2 1.6e-09 37.2 0.1 5.9 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 CAM59709.1 - 6.9e-06 24.4 2.2 0.0031 15.7 0.3 3.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PD40 PF07676.7 CAM59709.1 - 0.00019 20.9 0.0 1.1 8.9 0.0 3.0 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat DUF3312 PF11768.3 CAM59709.1 - 0.0022 16.3 0.0 0.0087 14.3 0.0 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF3312) eIF2A PF08662.6 CAM59709.1 - 0.004 16.8 0.0 0.83 9.3 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 CAM59709.1 - 0.076 12.4 0.1 12 5.2 0.0 2.7 2 1 0 2 2 2 0 PQQ-like domain Cytochrom_D1 PF02239.11 CAM59709.1 - 0.082 11.1 0.0 0.49 8.6 0.0 2.2 3 0 0 3 3 3 0 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 CAM59709.1 - 0.098 11.9 0.3 5.1 6.5 0.1 3.0 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature RCC1 PF00415.13 CAM59710.1 - 4.5e-48 161.2 48.6 1.1e-13 51.1 0.7 9.0 8 1 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CAM59710.1 - 3.8e-30 102.8 48.8 5.8e-12 44.8 2.8 8.3 8 1 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat BTB_2 PF02214.17 CAM59710.1 - 4e-06 26.9 0.0 0.072 13.3 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain PALP PF00291.20 CAM59711.1 - 7.6e-60 202.7 0.0 8.7e-60 202.5 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme 2Fe-2S_thioredx PF01257.14 CAM59713.1 - 1.8e-48 163.8 0.0 2.3e-48 163.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF2293 PF10056.4 CAM59713.1 - 0.13 12.2 0.5 0.28 11.1 0.3 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2293) Histone PF00125.19 CAM59714.1 - 5.5e-15 55.2 0.1 8.4e-15 54.6 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 zf-C3HC4_2 PF13923.1 CAM59715.1 - 1.7e-08 34.3 17.1 1.7e-08 34.3 11.9 3.5 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CAM59715.1 - 7.2e-08 31.9 17.4 7.2e-08 31.9 12.0 3.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CAM59715.1 - 2e-05 24.1 14.6 2e-05 24.1 10.1 3.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAM59715.1 - 4.3e-05 23.1 14.5 4.3e-05 23.1 10.0 2.5 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CAM59715.1 - 0.00014 21.6 16.2 0.00014 21.6 11.2 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 CAM59715.1 - 0.00019 21.2 18.9 0.00019 21.2 13.1 3.6 5 0 0 5 5 5 1 Ring finger domain zf-RING_UBOX PF13445.1 CAM59715.1 - 0.006 16.2 13.1 0.014 15.0 9.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger LSM PF01423.17 CAM59716.1 - 8e-06 25.3 0.0 2.7e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 LSM domain dsrm PF00035.20 CAM59719.1 - 0.087 13.4 0.0 20 5.8 0.0 2.6 2 0 0 2 2 2 0 Double-stranded RNA binding motif Cation_efflux PF01545.16 CAM59720.1 - 0.17 10.9 0.7 0.48 9.4 0.5 1.6 1 1 0 1 1 1 0 Cation efflux family Dus PF01207.12 CAM59721.1 - 1.5e-49 168.5 0.0 2.4e-49 167.8 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Hid1 PF12722.2 CAM59721.1 - 0.35 8.4 1.8 0.45 8.1 1.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein dCMP_cyt_deam_1 PF00383.17 CAM59722.1 - 2.9e-12 46.1 3.2 4.1e-12 45.6 2.2 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 CAM59722.1 - 1.1e-07 31.9 0.7 3.4e-06 27.0 0.7 2.1 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 CAM59722.1 - 0.0012 18.2 4.2 0.0042 16.4 2.9 1.8 1 1 0 1 1 1 1 A distinct subfamily of CDD/CDA-like deaminases Thioredoxin PF00085.15 CAM59722.1 - 0.043 13.4 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Sec20 PF03908.8 CAM59724.1 - 5.8e-05 22.7 0.8 5.8e-05 22.7 0.6 2.2 3 0 0 3 3 3 1 Sec20 V-SNARE_C PF12352.3 CAM59724.1 - 0.00086 19.3 3.1 0.00095 19.1 1.1 1.9 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Synaptobrevin PF00957.16 CAM59724.1 - 0.0091 15.5 4.4 0.011 15.3 1.3 2.2 1 1 1 2 2 2 1 Synaptobrevin MSC PF09402.5 CAM59724.1 - 0.012 14.3 0.4 0.017 13.8 0.3 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain V-SNARE PF05008.10 CAM59724.1 - 0.015 15.4 3.4 0.037 14.2 0.1 2.6 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Prominin PF05478.6 CAM59724.1 - 0.023 12.2 2.4 0.025 12.1 0.6 1.7 2 0 0 2 2 2 0 Prominin Baculo_11_kDa PF06143.6 CAM59724.1 - 0.042 13.2 0.3 0.087 12.2 0.2 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family Use1 PF09753.4 CAM59724.1 - 0.058 12.8 6.2 0.036 13.4 0.8 1.9 1 1 0 2 2 2 0 Membrane fusion protein Use1 Spore_III_AB PF09548.5 CAM59724.1 - 0.06 13.1 1.9 7.8 6.2 0.1 2.4 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Transcrip_act PF04949.8 CAM59724.1 - 0.5 9.9 3.5 0.26 10.9 0.5 1.8 2 1 0 2 2 2 0 Transcriptional activator Spc7 PF08317.6 CAM59724.1 - 1.1 7.8 4.6 1.2 7.6 0.6 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF883 PF05957.8 CAM59724.1 - 1.6 9.1 10.6 0.31 11.4 0.6 2.8 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF883) KxDL PF10241.4 CAM59724.1 - 5.5 6.9 7.6 0.47 10.3 1.3 2.1 3 0 0 3 3 2 0 Uncharacterized conserved protein EMP24_GP25L PF01105.19 CAM59724.1 - 8.1 6.1 7.1 45 3.6 0.0 2.6 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD MTBP_C PF14920.1 CAM59724.1 - 9.2 5.6 8.6 0.33 10.4 1.4 1.7 2 0 0 2 2 2 0 MDM2-binding DUF3450 PF11932.3 CAM59724.1 - 9.2 5.4 11.0 0.14 11.3 1.7 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) DUF1640 PF07798.6 CAM59726.1 - 0.0093 16.0 7.8 0.0093 16.0 5.4 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1640) TPR_MLP1_2 PF07926.7 CAM59726.1 - 0.013 15.2 13.7 0.041 13.6 9.5 1.9 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF972 PF06156.8 CAM59726.1 - 0.13 12.6 12.5 0.46 10.8 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF972) LOH1CR12 PF10158.4 CAM59726.1 - 9 6.0 12.6 0.97 9.2 0.5 2.9 2 1 1 3 3 3 0 Tumour suppressor protein TPR_2 PF07719.12 CAM59727.1 - 1.2e-16 59.1 1.1 0.00027 20.6 0.0 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 CAM59727.1 - 4.3e-13 48.7 0.5 5.7e-06 25.8 0.3 2.5 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.1 CAM59727.1 - 5.2e-10 38.3 3.1 0.015 15.0 0.2 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 CAM59727.1 - 4.4e-09 36.1 5.4 0.0009 19.1 0.7 4.1 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 CAM59727.1 - 5.2e-08 32.1 5.5 0.01 15.4 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 CAM59727.1 - 6.1e-07 29.1 0.3 1.1 9.5 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CAM59727.1 - 5.6e-06 26.5 0.0 5.2 7.9 0.0 4.1 3 1 1 4 4 3 2 Tetratricopeptide repeat Apc3 PF12895.2 CAM59727.1 - 1.5e-05 25.0 2.3 0.006 16.6 0.0 3.1 2 1 2 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CAM59727.1 - 1.8e-05 24.8 0.3 0.16 12.4 0.0 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 CAM59727.1 - 3.4e-05 23.3 3.5 0.12 12.2 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 CAM59727.1 - 3.7e-05 23.9 0.1 0.00062 20.0 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 CAM59727.1 - 5.4e-05 23.7 0.1 0.27 11.9 0.0 4.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 CAM59727.1 - 0.0064 16.3 0.5 1.2 9.1 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Peptidase_M20 PF01546.23 CAM59729.1 - 6e-14 51.9 0.1 9.3e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CAM59729.1 - 5.4e-08 32.5 0.0 1.1e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M42 PF05343.9 CAM59729.1 - 5.2e-06 25.4 0.0 3.9e-05 22.5 0.1 2.1 3 0 0 3 3 3 1 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.12 CAM59729.1 - 4e-05 23.4 0.0 8.6e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Sec3-PIP2_bind PF15277.1 CAM59729.1 - 0.062 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH DUF3508 PF12018.3 CAM59730.1 - 0.0066 15.4 0.2 1.9 7.3 0.0 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF3508) Pkinase PF00069.20 CAM59731.1 - 1e-58 198.5 0.0 2.2e-58 197.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM59731.1 - 1.8e-39 135.3 0.0 1.1e-38 132.7 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM59731.1 - 9e-08 31.4 0.0 2.5e-07 29.9 0.0 1.6 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 CAM59731.1 - 0.0046 16.0 0.0 0.0078 15.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CAM59731.1 - 0.0047 16.6 0.3 0.013 15.2 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family ANTH PF07651.11 CAM59731.1 - 0.011 14.4 0.0 0.027 13.1 0.0 1.6 1 0 0 1 1 1 0 ANTH domain zf-RING_2 PF13639.1 CAM59732.1 - 1.1e-10 41.1 8.1 1.1e-10 41.1 5.6 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 CAM59732.1 - 0.0029 17.2 6.7 0.0029 17.2 4.6 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAM59732.1 - 0.0031 17.4 8.2 0.012 15.6 5.7 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CAM59732.1 - 0.0063 16.5 3.1 0.0063 16.5 2.1 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CAM59732.1 - 0.0089 15.7 9.5 0.0089 15.7 6.6 2.0 2 0 0 2 2 2 1 zinc-RING finger domain CbiN PF02553.10 CAM59732.1 - 0.055 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Cobalt transport protein component CbiN zf-Nse PF11789.3 CAM59732.1 - 0.24 10.9 5.5 0.62 9.6 3.8 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 CAM59732.1 - 2.7 7.9 15.9 0.21 11.4 5.8 3.0 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING N6-adenineMlase PF10237.4 CAM59734.1 - 1.1e-41 142.1 1.8 1.8e-41 141.5 1.3 1.3 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Methyltransf_26 PF13659.1 CAM59734.1 - 0.053 13.5 0.0 0.2 11.6 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain FlxA PF14282.1 CAM59734.1 - 0.054 13.4 2.8 0.19 11.6 1.9 2.0 1 1 0 1 1 1 0 FlxA-like protein MTS PF05175.9 CAM59734.1 - 0.057 12.8 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain SoxD PF04267.7 CAM59734.1 - 0.082 12.7 0.2 0.29 10.9 0.1 1.9 1 0 0 1 1 1 0 Sarcosine oxidase, delta subunit family DUF1970 PF09301.5 CAM59736.1 - 0.011 15.7 0.5 0.011 15.7 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1970) Leu_zip PF15294.1 CAM59736.1 - 0.038 13.1 6.9 0.14 11.2 4.8 2.0 1 0 0 1 1 1 0 Leucine zipper Spc7 PF08317.6 CAM59736.1 - 5.7 5.4 6.5 12 4.4 4.5 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein DnaJ PF00226.26 CAM59738.1 - 1.6e-11 43.7 0.0 2.9e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain PhzC-PhzF PF02567.11 CAM59741.1 - 1.6e-34 119.4 1.0 8e-23 81.0 0.0 4.8 3 1 0 3 3 3 3 Phenazine biosynthesis-like protein Sigma70_r4 PF04545.11 CAM59741.1 - 0.0065 15.7 0.0 0.015 14.6 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 MSA-2c PF12238.3 CAM59741.1 - 0.081 12.5 0.7 0.13 11.8 0.5 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c Pkinase PF00069.20 CAM59742.1 - 1.9e-57 194.3 0.0 2.8e-57 193.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM59742.1 - 4.9e-39 133.9 0.0 7.3e-28 97.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase TFIIA PF03153.8 CAM59742.1 - 0.002 18.0 10.1 0.002 18.0 7.0 1.7 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Kinase-like PF14531.1 CAM59742.1 - 0.023 13.6 0.0 0.046 12.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like BUD22 PF09073.5 CAM59742.1 - 0.074 12.1 30.0 0.11 11.4 20.8 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 CAM59742.1 - 1.2 6.9 24.8 1.7 6.4 17.2 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 CAM59742.1 - 1.3 8.2 21.2 2.1 7.5 14.7 1.3 1 0 0 1 1 1 0 SDA1 SGT1 PF07093.6 CAM59742.1 - 1.7 6.9 11.6 2.6 6.3 8.1 1.2 1 0 0 1 1 1 0 SGT1 protein Daxx PF03344.10 CAM59742.1 - 2.1 6.7 23.6 3.2 6.1 16.3 1.2 1 0 0 1 1 1 0 Daxx Family IncA PF04156.9 CAM59746.2 - 0.0024 17.5 17.9 0.0024 17.5 12.4 3.7 3 1 0 3 3 3 1 IncA protein Sirohm_synth_C PF14823.1 CAM59746.2 - 0.0025 17.0 0.4 0.047 12.9 0.0 2.5 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal Uds1 PF15456.1 CAM59746.2 - 0.027 14.4 48.4 0.034 14.1 1.2 6.0 3 1 2 5 5 5 0 Up-regulated During Septation BCAS2 PF05700.6 CAM59746.2 - 0.033 13.6 20.5 0.0078 15.6 5.4 3.0 2 1 0 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) zf-ZPR1 PF03367.8 CAM59746.2 - 0.29 10.3 3.4 0.23 10.5 0.4 2.4 3 0 0 3 3 3 0 ZPR1 zinc-finger domain AAA_13 PF13166.1 CAM59746.2 - 6.5 5.0 17.1 0.12 10.8 6.2 2.0 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 CAM59747.1 - 3e-09 37.1 0.1 4e-08 33.5 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CAM59747.1 - 1.1e-06 27.6 0.0 0.0026 16.5 0.0 2.7 3 0 0 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_5 PF07728.9 CAM59747.1 - 3.3e-06 26.8 0.0 0.0012 18.5 0.0 3.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CAM59747.1 - 5.6e-06 26.4 0.2 5.6e-06 26.4 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 CAM59747.1 - 7.8e-06 26.7 0.1 2.3e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CAM59747.1 - 8.6e-06 25.9 0.1 3.6e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CAM59747.1 - 6.5e-05 22.9 0.2 0.00022 21.2 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CAM59747.1 - 0.00019 21.1 4.0 0.00019 21.1 2.8 2.4 2 0 0 2 2 1 1 Part of AAA domain AAA_18 PF13238.1 CAM59747.1 - 0.00034 20.9 0.0 0.00099 19.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 CAM59747.1 - 0.00075 18.7 0.0 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 RuvB_N PF05496.7 CAM59747.1 - 0.0019 17.2 0.1 0.0041 16.1 0.1 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NTPase_1 PF03266.10 CAM59747.1 - 0.002 17.8 0.1 0.0049 16.5 0.1 1.6 1 0 0 1 1 1 1 NTPase AAA_33 PF13671.1 CAM59747.1 - 0.003 17.4 0.0 0.003 17.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 CAM59747.1 - 0.0039 16.6 0.0 0.025 13.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CAM59747.1 - 0.021 14.7 0.0 0.052 13.4 0.0 1.6 2 0 0 2 2 1 0 AAA domain cobW PF02492.14 CAM59747.1 - 0.11 11.8 0.2 0.25 10.7 0.0 1.6 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 CAM59747.1 - 0.12 12.0 0.0 0.38 10.3 0.0 1.9 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.12 CAM59747.1 - 0.12 11.7 0.1 0.52 9.7 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein Polyoma_lg_T_C PF06431.6 CAM59747.1 - 0.18 10.4 0.0 0.33 9.5 0.0 1.3 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus RNA_helicase PF00910.17 CAM59747.1 - 0.19 11.8 0.0 0.62 10.2 0.0 1.9 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.12 CAM59747.1 - 0.29 10.6 0.0 0.48 9.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 CAM59747.1 - 0.36 10.4 0.0 0.63 9.6 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase RRM_1 PF00076.17 CAM59748.1 - 9.4e-13 47.6 0.8 1.4e-08 34.2 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM59748.1 - 3.6e-11 42.8 0.4 6.2e-06 26.1 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM59748.1 - 2.1e-10 40.2 0.3 2.7e-07 30.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NIPSNAP PF07978.8 CAM59748.1 - 0.06 13.3 0.4 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 NIPSNAP AsnC_trans_reg PF01037.16 CAM59748.1 - 0.1 12.3 0.0 3.3 7.4 0.0 2.5 2 0 0 2 2 2 0 AsnC family DUF732 PF05305.9 CAM59749.1 - 0.32 11.0 4.8 3.2 7.8 0.8 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF732) Metallophos PF00149.23 CAM59751.1 - 2.5e-05 23.7 0.0 5.9e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CAM59751.1 - 0.0058 16.4 0.1 0.0088 15.8 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain E1-E2_ATPase PF00122.15 CAM59753.1 - 2e-55 187.3 1.7 3.8e-55 186.4 1.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CAM59753.1 - 1.1e-39 135.8 4.7 2.8e-39 134.5 3.3 1.7 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CAM59753.1 - 8.3e-26 91.7 0.4 1.3e-24 87.8 0.3 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CAM59753.1 - 8.9e-17 60.8 0.0 2e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CAM59753.1 - 7.8e-13 47.6 0.0 2.4e-12 46.1 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CAM59753.1 - 6.3e-10 39.5 0.0 2.6e-09 37.5 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CAM59753.1 - 9.7e-05 22.0 0.6 0.00019 21.0 0.4 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3667 PF12412.3 CAM59753.1 - 0.19 11.0 0.0 0.39 10.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3667) ACBP PF00887.14 CAM59754.1 - 6.2e-33 112.3 1.1 5.9e-20 70.7 0.0 3.0 2 1 0 2 2 2 2 Acyl CoA binding protein ACBP PF00887.14 CAM59755.1 - 8.7e-30 102.2 0.2 1e-29 102.0 0.1 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein ACBP PF00887.14 CAM59757.1 - 1.8e-30 104.4 0.3 2e-30 104.2 0.2 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein Abhydrolase_6 PF12697.2 CAM59759.1 - 3.1e-08 33.8 4.0 5.2e-08 33.0 2.6 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAM59759.1 - 0.00053 19.6 0.0 0.00066 19.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 CAM59759.1 - 0.0064 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 CAM59759.1 - 0.011 15.4 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 CAM59759.1 - 0.059 12.9 0.2 0.13 11.9 0.2 1.5 1 0 0 1 1 1 0 Serine hydrolase EF-hand_7 PF13499.1 CAM59760.1 - 5.9e-15 55.1 0.0 1.4e-10 41.1 0.0 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CAM59760.1 - 6.2e-07 28.7 0.5 0.00091 18.9 0.0 3.6 3 1 1 4 4 4 2 EF-hand domain EF-hand_5 PF13202.1 CAM59760.1 - 3e-05 23.1 0.1 0.00017 20.8 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.27 CAM59760.1 - 4.3e-05 22.5 0.0 0.00077 18.6 0.0 3.1 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.1 CAM59760.1 - 0.035 13.7 0.5 1.7 8.3 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain pair GRAM PF02893.15 CAM59762.1 - 2.3e-09 36.6 1.3 1.3e-06 27.7 0.1 2.5 2 0 0 2 2 2 2 GRAM domain Pkinase PF00069.20 CAM59764.1 - 3e-67 226.5 0.0 3.8e-67 226.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain POLO_box PF00659.13 CAM59764.1 - 1.7e-44 149.5 0.0 1.4e-26 92.2 0.0 2.6 2 0 0 2 2 2 2 POLO box duplicated region Pkinase_Tyr PF07714.12 CAM59764.1 - 4e-38 130.9 0.0 5.4e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM59764.1 - 1.2e-10 40.8 0.0 6.8e-10 38.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CAM59764.1 - 0.00037 20.3 1.9 0.021 14.5 0.0 3.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family DUF4520 PF15016.1 CAM59764.1 - 0.018 14.6 0.0 0.43 10.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4520) Seadorna_VP7 PF07387.6 CAM59764.1 - 0.076 11.8 0.1 0.13 11.0 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF4404 PF14357.1 CAM59764.1 - 0.41 11.0 4.0 0.26 11.7 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) VID27 PF08553.5 CAM59765.1 - 1.3e-29 103.0 0.0 3e-29 101.8 0.0 1.5 2 0 0 2 2 2 1 VID27 cytoplasmic protein Pkinase PF00069.20 CAM59768.1 - 7.8e-22 77.6 0.0 9.9e-11 41.2 0.0 4.1 4 0 0 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.12 CAM59768.1 - 0.00044 19.3 0.0 0.076 12.0 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase NT5C PF06941.7 CAM59769.1 - 0.017 14.6 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Methyltransf_16 PF10294.4 CAM59771.1 - 4e-20 71.9 0.1 3e-15 56.1 0.0 2.4 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 CAM59771.1 - 0.00032 21.2 0.0 0.00066 20.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CAM59771.1 - 0.029 13.7 0.7 0.1 11.9 0.1 2.1 1 1 1 2 2 2 0 Methyltransferase small domain Methyltransf_26 PF13659.1 CAM59771.1 - 0.12 12.4 0.3 0.33 10.9 0.1 2.1 2 1 0 2 2 2 0 Methyltransferase domain Myb_DNA-binding PF00249.26 CAM59772.1 - 1e-17 63.8 4.1 7.4e-10 38.7 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CAM59772.1 - 4.5e-14 52.2 10.4 4.9e-09 36.1 0.3 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Peptidase_S9 PF00326.16 CAM59772.1 - 0.0046 16.2 2.0 0.47 9.6 0.1 2.8 3 0 0 3 3 3 2 Prolyl oligopeptidase family Myb_DNA-bind_4 PF13837.1 CAM59772.1 - 0.96 9.6 6.6 1.7 8.8 0.1 3.4 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain IMPDH PF00478.20 CAM59774.1 - 1.2e-132 442.0 2.1 1.5e-132 441.7 1.4 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 CAM59774.1 - 1.6e-14 53.3 0.0 1.5e-06 27.8 0.0 2.9 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 CAM59774.1 - 2.1e-08 33.4 3.4 3.9e-08 32.5 2.4 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 CAM59774.1 - 2.2e-06 27.0 10.7 0.0047 16.1 4.9 2.7 2 1 1 3 3 3 2 Nitronate monooxygenase PcrB PF01884.12 CAM59774.1 - 0.00033 19.9 9.3 0.0076 15.5 0.1 3.4 2 1 1 3 3 3 1 PcrB family His_biosynth PF00977.16 CAM59774.1 - 0.00041 19.6 2.4 0.016 14.5 0.1 2.3 1 1 0 2 2 2 1 Histidine biosynthesis protein Beta_elim_lyase PF01212.16 CAM59774.1 - 0.00081 18.6 0.4 0.0014 17.8 0.3 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DHO_dh PF01180.16 CAM59774.1 - 0.0024 16.9 4.8 0.019 13.9 0.4 2.3 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.12 CAM59774.1 - 0.0037 16.2 4.7 0.0072 15.2 3.2 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 CAM59774.1 - 0.0041 16.2 0.8 0.0041 16.2 0.5 2.5 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG ParA PF10609.4 CAM59774.1 - 0.041 13.7 1.1 3.7 7.5 0.0 3.3 3 0 0 3 3 3 0 ParA/MinD ATPase like Lysine_decarbox PF03641.9 CAM59775.1 - 7.8e-28 96.9 0.2 1.2e-27 96.2 0.2 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase ABM PF03992.11 CAM59775.1 - 1.4e-08 34.6 0.0 2.9e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Kinesin PF00225.18 CAM59776.1 - 4e-103 344.6 0.1 4e-103 344.6 0.0 2.6 2 1 1 3 3 3 1 Kinesin motor domain Reo_sigmaC PF04582.7 CAM59776.1 - 0.65 9.1 28.1 0.87 8.6 1.1 4.7 2 1 2 5 5 5 0 Reovirus sigma C capsid protein CENP-Q PF13094.1 CAM59777.1 - 0.0061 16.6 2.3 0.0061 16.6 1.6 1.7 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Laminin_II PF06009.7 CAM59777.1 - 0.035 13.8 0.4 0.27 10.9 0.1 2.1 2 0 0 2 2 2 0 Laminin Domain II G-patch PF01585.18 CAM59778.1 - 8.2e-13 47.9 0.4 1.6e-12 46.9 0.3 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CAM59778.1 - 0.0018 18.0 0.3 0.0018 18.0 0.2 2.0 2 0 0 2 2 2 1 DExH-box splicing factor binding site Ebola_NP PF05505.7 CAM59778.1 - 0.1 10.6 4.0 0.12 10.4 2.8 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein Macoilin PF09726.4 CAM59778.1 - 0.46 8.6 6.8 0.52 8.5 4.7 1.0 1 0 0 1 1 1 0 Transmembrane protein Pol_alpha_B_N PF08418.5 CAM59778.1 - 1.1 8.6 5.8 1.5 8.2 4.0 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF3827 PF12877.2 CAM59778.1 - 1.8 6.5 9.4 2.1 6.3 6.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DBR1 PF05011.8 CAM59780.1 - 2.5e-06 27.4 0.0 5.2e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 CAM59780.1 - 0.003 16.9 0.1 0.012 14.9 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CAM59780.1 - 0.013 15.3 0.1 0.045 13.6 0.1 1.9 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain ATP-synt_10 PF05176.9 CAM59781.1 - 0.0012 18.1 0.0 0.0022 17.2 0.0 1.5 1 0 0 1 1 1 1 ATP10 protein FERM_M PF00373.13 CAM59782.1 - 0.12 12.5 0.9 0.15 12.2 0.6 1.3 1 0 0 1 1 1 0 FERM central domain Suf PF05843.9 CAM59783.1 - 0.36 10.4 2.4 0.46 10.1 1.7 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF1935 PF09149.5 CAM59784.1 - 3.1e-34 117.0 0.0 7.2e-34 115.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) META PF03724.11 CAM59784.1 - 8.9e-24 83.2 1.5 1.8e-09 37.3 0.0 3.3 3 0 0 3 3 3 3 META domain Yae1_N PF09811.4 CAM59784.1 - 0.13 11.8 2.1 42 3.7 0.1 3.3 3 0 0 3 3 3 0 Essential protein Yae1, N terminal META PF03724.11 CAM59786.1 - 5.9e-12 45.2 0.0 7e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 META domain LRR_6 PF13516.1 CAM59787.1 - 3.6e-12 45.0 0.4 1.2 9.4 0.0 6.8 6 0 0 6 6 6 3 Leucine Rich repeat LRR_4 PF12799.2 CAM59787.1 - 1.5e-09 37.2 0.1 0.12 12.0 0.0 3.8 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CAM59787.1 - 1.4e-05 24.4 0.2 12 6.3 0.0 5.9 5 1 0 5 5 5 1 Leucine Rich Repeat LRR_7 PF13504.1 CAM59787.1 - 0.013 15.5 6.2 27 5.5 0.0 5.8 6 0 0 6 6 6 0 Leucine rich repeat Hamartin PF04388.7 CAM59787.1 - 0.62 8.6 4.1 0.88 8.1 2.9 1.1 1 0 0 1 1 1 0 Hamartin protein Acyltransferase PF01553.16 CAM59788.1 - 2.1e-13 49.8 0.0 3.4e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Sec63 PF02889.11 CAM59789.2 - 1.3e-63 215.1 0.0 1.2e-56 192.2 0.0 2.6 2 1 0 2 2 2 2 Sec63 Brl domain Helicase_C PF00271.26 CAM59789.2 - 1.2e-08 34.6 0.0 3e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAM59789.2 - 1.1e-07 31.4 0.0 2.9e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase FH2 PF02181.18 CAM59790.1 - 1.3e-51 175.6 0.0 2.1e-51 174.9 0.0 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain Med9 PF07544.8 CAM59790.1 - 2.1e-06 27.3 0.2 6.1e-06 25.8 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 CUE PF02845.11 CAM59790.1 - 0.0054 16.1 0.1 0.029 13.8 0.0 2.1 2 0 0 2 2 2 1 CUE domain CorA PF01544.13 CAM59790.1 - 0.0078 15.2 0.1 0.02 13.9 0.1 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein PCIF1_WW PF12237.3 CAM59791.1 - 5.9e-35 120.1 0.0 1.1e-33 115.9 0.0 2.7 2 1 0 2 2 2 1 Phosphorylated CTD interacting factor 1 WW domain PDEase_I PF00233.14 CAM59792.2 - 3.1e-10 40.1 0.5 1.6e-06 28.0 0.1 2.3 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase BTB PF00651.26 CAM59793.1 - 0.13 12.2 0.0 0.83 9.6 0.0 2.0 2 0 0 2 2 2 0 BTB/POZ domain Mak10 PF04112.8 CAM59794.1 - 1.2e-07 31.0 0.0 5.6e-07 28.9 0.0 2.1 1 1 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase PI3_PI4_kinase PF00454.22 CAM59795.2 - 0.002 17.6 0.0 0.0039 16.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Abhydrolase_6 PF12697.2 CAM59797.1 - 9.8e-26 91.0 0.3 1.5e-25 90.4 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAM59797.1 - 1.6e-16 60.6 0.0 4.4e-16 59.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CAM59797.1 - 3.6e-12 46.2 0.0 5.9e-12 45.5 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 CAM59797.1 - 0.0005 19.9 0.0 0.00094 19.0 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein FSH1 PF03959.8 CAM59797.1 - 0.0021 17.5 0.0 0.0035 16.8 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Esterase PF00756.15 CAM59797.1 - 0.016 14.6 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.16 CAM59797.1 - 0.019 14.1 0.1 0.12 11.5 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF2048 PF09752.4 CAM59797.1 - 0.051 12.4 0.4 0.087 11.6 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Abhydrolase_2 PF02230.11 CAM59797.1 - 0.053 12.9 0.0 0.76 9.1 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Ndr PF03096.9 CAM59797.1 - 0.15 10.5 0.0 0.32 9.4 0.0 1.4 2 0 0 2 2 2 0 Ndr family BAAT_C PF08840.6 CAM59797.1 - 0.2 11.3 0.0 1 8.9 0.0 1.9 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal GlcNAc PF11397.3 CAM59798.1 - 6.2e-137 456.3 0.0 7.5e-137 456.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) DUF2452 PF10504.4 CAM59798.1 - 0.21 10.8 0.0 0.35 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) RPA_C PF08784.6 CAM59799.2 - 0.51 10.7 5.0 0.75 10.2 1.4 2.9 3 0 0 3 3 3 0 Replication protein A C terminal Abhydrolase_6 PF12697.2 CAM59800.1 - 7.1e-23 81.6 3.5 2.3e-22 79.9 2.4 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAM59800.1 - 1.5e-14 54.1 0.2 6.5e-13 48.7 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CAM59800.1 - 4.1e-11 42.8 0.1 4.5e-10 39.4 0.1 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 CAM59800.1 - 4.1e-05 23.4 0.0 0.00011 22.0 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Esterase_phd PF10503.4 CAM59800.1 - 6.2e-05 22.3 0.4 0.11 11.7 0.0 2.4 2 0 0 2 2 2 2 Esterase PHB depolymerase Ndr PF03096.9 CAM59800.1 - 0.00071 18.1 0.0 0.0012 17.4 0.0 1.3 1 0 0 1 1 1 1 Ndr family Ser_hydrolase PF06821.8 CAM59800.1 - 0.0027 17.3 0.0 0.0055 16.3 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_3 PF07859.8 CAM59800.1 - 0.013 15.0 0.0 0.59 9.6 0.0 2.6 3 0 0 3 3 3 0 alpha/beta hydrolase fold Esterase PF00756.15 CAM59800.1 - 0.021 14.2 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Putative esterase FSH1 PF03959.8 CAM59800.1 - 0.052 12.9 0.0 0.22 10.9 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 CAM59800.1 - 0.088 12.0 0.0 8.1 5.5 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF2048 PF09752.4 CAM59800.1 - 0.097 11.5 0.0 1.8 7.3 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) Patatin PF01734.17 CAM59800.1 - 0.11 12.3 0.5 0.29 11.0 0.2 1.5 1 1 0 1 1 1 0 Patatin-like phospholipase PGAP1 PF07819.8 CAM59800.1 - 0.13 11.7 0.1 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.2 CAM59801.1 - 9.8e-31 107.3 1.3 1.3e-30 106.9 0.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAM59801.1 - 1.8e-17 63.6 0.0 3.1e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CAM59801.1 - 7.3e-14 51.7 0.0 1.9e-13 50.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 CAM59801.1 - 7.8e-06 25.2 0.1 0.0013 18.0 0.0 2.2 2 0 0 2 2 2 2 Esterase PHB depolymerase Esterase PF00756.15 CAM59801.1 - 9.1e-05 21.9 0.0 0.00023 20.6 0.0 1.6 2 0 0 2 2 2 1 Putative esterase Ndr PF03096.9 CAM59801.1 - 0.0008 17.9 0.0 0.0033 15.9 0.0 1.8 2 0 0 2 2 2 1 Ndr family Abhydrolase_2 PF02230.11 CAM59801.1 - 0.0024 17.3 0.0 0.19 11.1 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.5 CAM59801.1 - 0.0029 17.4 0.0 0.0055 16.5 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.3 CAM59801.1 - 0.0057 16.4 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 CAM59801.1 - 0.023 13.9 0.0 1.9 7.7 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family FIST PF08495.5 CAM59801.1 - 0.038 13.1 0.0 0.074 12.1 0.0 1.5 2 0 0 2 2 2 0 FIST N domain DUF2048 PF09752.4 CAM59801.1 - 0.093 11.5 0.3 0.14 10.9 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Abhydrolase_6 PF12697.2 CAM59802.1 - 1.5e-23 83.8 3.2 1.5e-23 83.8 2.2 2.8 2 1 1 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAM59802.1 - 2e-15 56.9 0.0 4.6e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CAM59802.1 - 7.3e-12 45.2 0.0 7.3e-12 45.2 0.0 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 CAM59802.1 - 0.00039 20.2 0.3 0.0018 18.1 0.0 2.2 2 0 0 2 2 2 1 TAP-like protein Thioesterase PF00975.15 CAM59802.1 - 0.0072 16.5 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S9 PF00326.16 CAM59802.1 - 0.038 13.2 0.1 1.8 7.7 0.0 2.7 3 0 0 3 3 3 0 Prolyl oligopeptidase family Esterase PF00756.15 CAM59802.1 - 0.075 12.4 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative esterase DUF2048 PF09752.4 CAM59802.1 - 0.098 11.5 0.2 0.21 10.4 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) ThiG PF05690.9 CAM59802.1 - 0.27 10.2 10.4 2.8 6.9 0.0 2.4 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG PLAC8 PF04749.12 CAM59803.1 - 3.7 8.1 19.2 0.62 10.6 8.7 2.8 2 2 0 2 2 2 0 PLAC8 family DUF4570 PF15134.1 CAM59804.1 - 0.0076 16.0 4.3 0.015 15.1 3.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4570) ApbA_C PF08546.6 CAM59804.1 - 0.91 9.5 3.4 1.2 9.1 1.2 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal UCH PF00443.24 CAM59805.1 - 2.1e-15 56.5 0.0 3.3e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CAM59805.1 - 8.1e-09 35.3 0.0 1.9e-08 34.0 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Steroid_dh PF02544.11 CAM59806.1 - 4e-25 88.3 1.2 7.2e-10 38.8 0.0 4.3 4 0 0 4 4 4 4 3-oxo-5-alpha-steroid 4-dehydrogenase Kinesin PF00225.18 CAM59807.1 - 5.6e-86 288.2 0.1 8.7e-86 287.6 0.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain Calpain_III PF01067.17 CAM59807.1 - 1.2e-27 96.4 0.4 4.2e-21 75.1 0.0 2.9 3 0 0 3 3 3 2 Calpain large subunit, domain III Arm PF00514.18 CAM59807.1 - 1.2e-06 28.1 6.2 0.26 11.1 0.1 5.7 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat Nol1_Nop2_Fmu PF01189.12 CAM59809.1 - 2.8e-24 85.9 0.0 4e-15 55.9 0.0 2.8 2 1 0 2 2 2 2 NOL1/NOP2/sun family WW PF00397.21 CAM59810.1 - 1.9e-09 37.1 0.2 5e-09 35.8 0.2 1.8 1 0 0 1 1 1 1 WW domain DUF746 PF05344.6 CAM59810.1 - 0.0076 15.7 0.1 0.076 12.5 0.0 2.4 2 0 0 2 2 2 1 Domain of Unknown Function (DUF746) GP41 PF00517.12 CAM59810.1 - 2.7 7.5 6.5 0.47 9.9 0.8 2.3 2 0 0 2 2 2 0 Retroviral envelope protein XRN_N PF03159.13 CAM59811.1 - 1.1e-63 214.8 0.0 1.1e-31 110.1 0.0 2.2 2 0 0 2 2 2 2 XRN 5'-3' exonuclease N-terminus zf-RanBP PF00641.13 CAM59811.1 - 7e-07 28.2 2.6 1.7e-06 27.0 1.8 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others UDPGP PF01704.13 CAM59812.1 - 1.8e-08 33.2 0.0 3.2e-08 32.5 0.0 1.4 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NUFIP2 PF15293.1 CAM59815.1 - 0.27 9.8 2.2 0.53 8.9 1.6 1.5 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 2 ATG16 PF08614.6 CAM59816.2 - 6.4e-06 26.1 6.4 0.0025 17.6 1.4 3.0 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) ADIP PF11559.3 CAM59816.2 - 0.0086 15.9 0.5 0.0086 15.9 0.4 2.7 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding Cast PF10174.4 CAM59816.2 - 0.0097 14.0 6.7 0.1 10.6 0.5 2.2 2 0 0 2 2 2 2 RIM-binding protein of the cytomatrix active zone DUF3373 PF11853.3 CAM59816.2 - 0.78 8.1 2.4 3.1 6.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) CtIP_N PF10482.4 CAM59816.2 - 0.83 9.4 5.5 0.15 11.8 0.4 2.1 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain TMF_TATA_bd PF12325.3 CAM59816.2 - 1.1 9.0 9.2 2.2 8.0 1.3 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4200 PF13863.1 CAM59816.2 - 2.4 8.1 7.0 1.2 9.0 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF3584 PF12128.3 CAM59816.2 - 2.4 5.3 7.0 2.8 5.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF4266 PF14086.1 CAM59816.2 - 5.1 7.6 7.7 0.74 10.3 0.4 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4266) Motile_Sperm PF00635.21 CAM59817.1 - 2e-10 40.2 0.0 3.6e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Histone PF00125.19 CAM59818.1 - 6.9e-14 51.7 1.7 9.1e-14 51.3 1.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DNA_photolyase PF00875.13 CAM59818.1 - 0.011 15.4 0.0 0.013 15.2 0.0 1.1 1 0 0 1 1 1 0 DNA photolyase CBFD_NFYB_HMF PF00808.18 CAM59818.1 - 0.012 15.6 0.5 0.022 14.7 0.3 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF4661 PF15576.1 CAM59819.2 - 0.041 13.5 1.0 0.11 12.1 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) TPR_11 PF13414.1 CAM59820.1 - 8.9e-09 34.8 1.1 0.0073 15.9 0.0 4.6 2 1 2 4 4 4 3 TPR repeat TPR_2 PF07719.12 CAM59820.1 - 1.6e-07 30.6 1.3 0.17 11.8 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 CAM59820.1 - 2.1e-05 24.3 0.0 2.1 8.7 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CAM59820.1 - 2.3e-05 24.5 17.0 1.2 9.9 0.0 7.5 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 CAM59820.1 - 0.00035 21.1 3.6 0.13 12.9 0.2 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CAM59820.1 - 0.016 14.7 0.0 2.9 7.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat GNAT_acetyltr_2 PF13718.1 CAM59821.1 - 2.4e-70 235.8 0.0 5.4e-70 234.7 0.0 1.6 2 0 0 2 2 2 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 CAM59821.1 - 4.9e-60 202.1 0.0 1.6e-59 200.5 0.0 1.9 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 CAM59821.1 - 6.7e-35 118.6 0.1 2.4e-34 116.8 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 CAM59821.1 - 5.9e-15 55.2 0.0 1.7e-14 53.6 0.0 1.9 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 CAM59821.1 - 0.066 13.3 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2742 PF10888.3 CAM59821.1 - 0.18 11.7 1.5 0.45 10.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2742) Oscp1 PF10188.4 CAM59822.1 - 4.1e-63 212.2 0.3 5.9e-63 211.7 0.2 1.2 1 0 0 1 1 1 1 Organic solute transport protein 1 Sterol-sensing PF12349.3 CAM59822.1 - 0.043 13.2 0.5 0.067 12.6 0.4 1.3 1 0 0 1 1 1 0 Sterol-sensing domain of SREBP cleavage-activation eIF2A PF08662.6 CAM59825.1 - 3.9e-13 49.5 0.0 1.1e-12 48.1 0.0 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A DUF3846 PF12957.2 CAM59825.1 - 0.15 11.8 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3846) SH3_1 PF00018.23 CAM59826.1 - 0.071 12.5 0.5 0.16 11.4 0.0 1.8 2 0 0 2 2 2 0 SH3 domain Methyltransf_32 PF13679.1 CAM59827.2 - 4.4e-13 49.1 0.9 6.9e-07 29.0 0.1 2.7 2 1 0 2 2 2 2 Methyltransferase domain Ribosomal_L25p PF01386.14 CAM59829.1 - 0.029 14.4 0.0 0.052 13.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal L25p family CTP_transf_2 PF01467.21 CAM59830.1 - 1.6e-20 73.7 0.0 2.6e-20 73.0 0.0 1.4 1 1 0 1 1 1 1 Cytidylyltransferase Cyt-b5 PF00173.23 CAM59831.1 - 2.8e-16 59.0 0.0 4e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain C_GCAxxG_C_C PF09719.5 CAM59831.1 - 0.11 12.3 0.2 0.34 10.7 0.3 1.8 2 1 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) ALO PF04030.9 CAM59832.1 - 1.6e-72 244.1 2.2 5.8e-69 232.5 0.3 2.1 2 0 0 2 2 2 2 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 CAM59832.1 - 2.4e-23 82.1 0.4 4.3e-23 81.3 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain SDA1 PF05285.7 CAM59833.1 - 7.4e-102 340.9 64.9 1.9e-52 178.5 34.2 2.8 2 1 1 3 3 3 2 SDA1 NUC130_3NT PF08158.7 CAM59833.1 - 1.7e-16 60.2 0.2 4.4e-16 58.9 0.1 1.8 1 0 0 1 1 1 1 NUC130/3NT domain IQ PF00612.22 CAM59835.1 - 1.5e-08 33.5 61.9 0.023 14.2 1.2 9.0 9 0 0 9 9 9 6 IQ calmodulin-binding motif Inositol_P PF00459.20 CAM59836.1 - 1.5e-52 178.5 0.2 1.8e-52 178.3 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Peptidase_C65 PF10275.4 CAM59837.1 - 1.9e-58 197.6 0.0 2.2e-58 197.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.14 CAM59837.1 - 6.7e-06 26.7 0.7 0.019 15.5 0.0 2.7 2 1 0 3 3 3 2 OTU-like cysteine protease zf-ZPR1 PF03367.8 CAM59838.1 - 2.2e-105 348.7 0.0 3e-53 179.2 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain Pro_racemase PF05544.6 CAM59838.1 - 0.06 12.1 0.0 0.099 11.4 0.0 1.3 1 0 0 1 1 1 0 Proline racemase Zn-ribbon_8 PF09723.5 CAM59838.1 - 0.46 10.4 10.4 20 5.2 0.1 4.4 4 0 0 4 4 4 0 Zinc ribbon domain DUF2387 PF09526.5 CAM59838.1 - 1.5 8.8 11.2 0.28 11.1 0.1 3.3 3 0 0 3 3 3 0 Probable metal-binding protein (DUF2387) LLC1 PF14945.1 CAM59839.1 - 0.69 10.2 3.6 2.7 8.3 0.0 2.7 1 1 2 3 3 3 0 Normal lung function maintenance, Low in Lung Cancer 1 protein DltD_M PF04918.7 CAM59839.1 - 1.2 9.3 6.0 2.3 8.3 4.1 1.7 1 1 0 1 1 1 0 DltD central region MFS_1 PF07690.11 CAM59840.1 - 1.4e-20 73.3 35.8 1.4e-20 73.3 24.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ion_trans PF00520.26 CAM59841.1 - 7.1e-61 204.9 54.3 1.8e-22 79.6 5.9 4.8 5 0 0 5 5 5 4 Ion transport protein Sec62 PF03839.11 CAM59841.1 - 5.4 6.3 3.5 28 4.0 0.1 2.6 2 0 0 2 2 2 0 Translocation protein Sec62 RabGAP-TBC PF00566.13 CAM59842.1 - 3.6e-16 59.2 0.5 6.7e-16 58.4 0.3 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ferrochelatase PF00762.14 CAM59843.1 - 5.6e-68 229.2 0.1 5.4e-53 180.0 0.0 2.1 2 0 0 2 2 2 2 Ferrochelatase Smoothelin PF12510.3 CAM59844.1 - 0.012 15.4 3.5 1.6 8.6 0.6 2.4 2 0 0 2 2 2 0 Smoothelin cytoskeleton protein Med3 PF11593.3 CAM59844.1 - 2.2 7.4 12.1 5 6.2 8.4 1.5 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal Arg_tRNA_synt_N PF03485.11 CAM59844.1 - 2.8 8.5 6.3 0.88 10.1 0.1 2.6 2 1 1 3 3 3 0 Arginyl tRNA synthetase N terminal domain ABC_tran PF00005.22 CAM59990.1 - 1.5e-46 158.0 4.1 4.4e-22 78.8 0.0 3.8 4 0 0 4 4 3 2 ABC transporter ABC_tran_2 PF12848.2 CAM59990.1 - 4.2e-24 84.1 4.1 4.2e-24 84.1 2.9 3.3 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.1 CAM59990.1 - 1.8e-19 70.8 4.2 0.0001 22.3 0.3 4.4 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 CAM59990.1 - 8.9e-11 41.4 1.5 0.0061 15.8 0.1 4.2 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CAM59990.1 - 2.7e-08 33.2 0.3 0.0025 17.3 0.0 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CAM59990.1 - 3.1e-08 34.4 0.0 0.00022 22.0 0.0 3.1 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 CAM59990.1 - 5.3e-07 28.9 0.1 0.0058 15.8 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 CAM59990.1 - 2.2e-06 27.7 3.0 0.0061 16.5 0.3 2.8 2 1 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 CAM59990.1 - 2.2e-06 27.5 0.1 0.11 12.4 0.0 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_15 PF13175.1 CAM59990.1 - 6.6e-06 25.4 6.4 0.57 9.1 0.0 5.0 3 1 1 5 5 5 1 AAA ATPase domain Miro PF08477.8 CAM59990.1 - 7.3e-06 26.4 0.1 0.09 13.2 0.0 3.0 3 0 0 3 3 2 2 Miro-like protein AAA_33 PF13671.1 CAM59990.1 - 1.8e-05 24.6 2.6 0.078 12.8 0.0 3.6 3 1 0 3 3 3 2 AAA domain NACHT PF05729.7 CAM59990.1 - 4.1e-05 23.3 0.1 0.43 10.2 0.0 3.2 3 0 0 3 3 3 2 NACHT domain AAA_22 PF13401.1 CAM59990.1 - 0.00021 21.4 1.3 0.28 11.3 0.1 3.5 2 2 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CAM59990.1 - 0.00021 20.7 0.4 1.1 8.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.1 CAM59990.1 - 0.00022 21.2 5.9 0.024 14.5 0.0 3.6 4 0 0 4 4 3 2 AAA domain AAA_23 PF13476.1 CAM59990.1 - 0.00031 21.1 12.6 0.078 13.2 0.0 4.3 5 0 0 5 5 4 2 AAA domain AAA_18 PF13238.1 CAM59990.1 - 0.00063 20.0 2.0 0.13 12.5 0.0 3.8 4 0 0 4 4 3 1 AAA domain AAA_30 PF13604.1 CAM59990.1 - 0.00088 18.8 1.6 0.89 9.0 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA PF00004.24 CAM59990.1 - 0.00094 19.3 0.0 0.83 9.8 0.0 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 CAM59990.1 - 0.0011 18.4 0.0 0.061 12.8 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 CAM59990.1 - 0.0011 18.7 0.2 1.1 8.9 0.0 3.2 2 1 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 CAM59990.1 - 0.0017 18.1 0.1 0.4 10.6 0.0 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 CAM59990.1 - 0.0019 18.3 0.0 0.6 10.3 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.1 CAM59990.1 - 0.002 18.0 0.0 4.9 7.0 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.9 CAM59990.1 - 0.0026 17.4 0.1 2.3 7.9 0.0 3.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Dynamin_N PF00350.18 CAM59990.1 - 0.0081 15.9 5.3 1.8 8.3 0.0 4.1 4 2 0 4 4 4 1 Dynamin family cobW PF02492.14 CAM59990.1 - 0.012 15.0 0.1 0.35 10.2 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 CAM59990.1 - 0.013 15.0 0.1 0.56 9.8 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 CAM59990.1 - 0.018 14.7 0.2 5 6.7 0.0 3.3 3 0 0 3 3 3 0 Archaeal ATPase SRP54 PF00448.17 CAM59990.1 - 0.02 14.3 0.3 4.8 6.5 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.13 CAM59990.1 - 0.031 13.7 4.0 1.9 7.9 0.0 3.2 2 1 0 2 2 2 0 FtsK/SpoIIIE family FeoB_N PF02421.13 CAM59990.1 - 0.033 13.4 0.1 1.3 8.2 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Arf PF00025.16 CAM59990.1 - 0.049 12.8 2.1 1.8 7.7 0.0 3.3 4 0 0 4 4 4 0 ADP-ribosylation factor family AAA_10 PF12846.2 CAM59990.1 - 0.69 9.2 8.4 3.2 7.0 0.1 3.6 4 1 0 5 5 4 0 AAA-like domain ATP_bind_1 PF03029.12 CAM59990.1 - 1.1 8.7 4.7 17 4.8 0.1 3.2 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein Septin PF00735.13 CAM59990.1 - 2.1 7.2 7.9 2.4 7.0 0.0 3.1 4 0 0 4 4 4 0 Septin AF-4 PF05110.8 CAM59991.1 - 0.1 10.4 2.0 0.15 9.9 1.4 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein zf-C2H2_3 PF13878.1 CAM59992.1 - 3.5e-13 48.8 0.0 9.4e-13 47.5 0.0 1.7 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO zf-CCCH PF00642.19 CAM59993.1 - 5.4e-08 32.3 7.9 0.00011 21.7 0.5 2.9 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.17 CAM59993.1 - 3.6e-06 26.5 0.0 4.5e-05 23.0 0.0 2.4 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM59993.1 - 0.075 12.8 0.0 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Herpes_UL87 PF03043.9 CAM59993.1 - 0.078 11.3 0.2 0.1 10.9 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family zf-CCCH_2 PF14608.1 CAM59993.1 - 1.7 8.7 8.3 4.2 7.5 1.2 2.7 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Aldedh PF00171.17 CAM59994.1 - 2.7e-105 352.4 0.0 3.2e-105 352.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pkinase PF00069.20 CAM59995.1 - 2.9e-56 190.5 0.0 3.7e-56 190.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM59995.1 - 1.8e-29 102.5 0.0 3.7e-29 101.5 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CAM59995.1 - 0.0036 17.0 2.0 2.6 7.7 0.0 2.9 1 1 2 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.17 CAM59995.1 - 0.012 14.9 0.0 0.021 14.1 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 CAM59995.1 - 0.016 14.3 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CAM59995.1 - 0.08 11.8 0.0 0.25 10.2 0.0 1.7 1 1 0 1 1 1 0 Kinase-like AMP-binding PF00501.23 CAM59997.1 - 2.4e-84 283.1 0.1 3.2e-84 282.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Ribosomal_L38e PF01781.13 CAM59999.1 - 6.2e-31 105.9 3.8 7.4e-31 105.7 2.6 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Apolipoprotein PF01442.13 CAM60001.1 - 1.9e-264 869.8 803.0 1.2e-27 96.7 44.0 16.6 1 1 14 15 15 15 13 Apolipoprotein A1/A4/E domain Flg_hook PF02120.11 CAM60001.1 - 1.4e-30 104.7 380.0 0.71 9.5 3.4 33.8 2 1 32 34 34 34 31 Flagellar hook-length control protein FliK FYVE PF01363.16 CAM60001.1 - 2.8e-11 43.1 7.6 6.5e-11 41.9 5.3 1.7 1 0 0 1 1 1 1 FYVE zinc finger DivIC PF04977.10 CAM60001.1 - 1e-09 37.7 447.7 1.6 8.2 4.6 38.3 5 2 33 39 39 39 33 Septum formation initiator DUF3618 PF12277.3 CAM60001.1 - 3.4e-07 30.1 537.4 1.8 8.6 5.3 39.8 19 10 3 36 36 36 31 Protein of unknown function (DUF3618) GAS PF13851.1 CAM60001.1 - 0.0076 15.4 323.7 0.31 10.1 10.5 16.7 3 2 27 30 30 30 21 Growth-arrest specific micro-tubule binding DUF1492 PF07374.6 CAM60001.1 - 0.088 12.9 174.8 18 5.4 0.2 32.0 2 1 32 34 34 34 0 Protein of unknown function (DUF1492) IBR PF01485.16 CAM60001.1 - 0.96 9.3 5.8 2.5 8.0 4.0 1.6 1 0 0 1 1 1 0 IBR domain DUF4206 PF13901.1 CAM60002.1 - 1.8e-12 47.2 2.5 0.015 14.8 0.0 4.8 4 1 0 4 4 4 4 Domain of unknown function (DUF4206) DDRGK PF09756.4 CAM60007.1 - 1.2e-26 93.3 26.1 1.6e-17 63.4 0.0 2.2 2 0 0 2 2 2 2 DDRGK domain DUF4461 PF14688.1 CAM60007.1 - 0.077 12.3 0.3 0.077 12.3 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4461) FAM117 PF15388.1 CAM60007.1 - 1.6 7.9 6.9 2.6 7.2 4.8 1.3 1 0 0 1 1 1 0 Protein Family FAM117 BTV_NS2 PF04514.7 CAM60007.1 - 6.6 5.5 13.3 11 4.7 9.2 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 MRP-S31 PF15433.1 CAM60007.1 - 7.3 5.9 12.7 10 5.4 8.8 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Pkinase PF00069.20 CAM60008.1 - 4.4e-33 114.5 0.0 5.8e-24 84.6 0.0 3.7 4 1 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 CAM60008.1 - 1.4e-14 53.8 0.0 3.5e-09 36.1 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 CAM60008.1 - 0.00097 18.1 0.0 0.0025 16.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.15 CAM60008.1 - 0.34 10.4 0.6 26 4.2 0.2 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 CAM60008.1 - 0.46 9.2 0.0 0.82 8.3 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Grp1_Fun34_YaaH PF01184.14 CAM60010.1 - 2.3e-35 121.8 10.5 3.1e-35 121.3 7.3 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family NfeD PF01957.13 CAM60010.1 - 7.2 6.7 7.9 0.23 11.5 0.2 2.2 2 1 0 2 2 2 0 NfeD-like C-terminal, partner-binding Grp1_Fun34_YaaH PF01184.14 CAM60011.1 - 1.3e-56 191.2 16.2 1.7e-56 190.8 11.2 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF443 PF04276.7 CAM60011.1 - 0.93 8.8 5.0 2.2 7.6 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF443) Grp1_Fun34_YaaH PF01184.14 CAM60012.1 - 6.4e-11 41.9 0.5 1.2e-10 41.0 0.3 1.4 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Grp1_Fun34_YaaH PF01184.14 CAM60013.1 - 6.8e-56 188.8 15.8 9.4e-56 188.4 11.0 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF443 PF04276.7 CAM60013.1 - 0.67 9.3 5.0 1.6 8.1 3.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF443) MFS_1 PF07690.11 CAM60014.1 - 8.9e-32 110.1 14.9 2.4e-19 69.2 0.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 CAM60014.1 - 9.5e-06 23.9 0.0 0.00029 19.0 0.0 2.6 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family ResB PF05140.9 CAM60014.1 - 0.046 12.2 0.0 0.075 11.5 0.0 1.3 1 0 0 1 1 1 0 ResB-like family DUF1228 PF06779.9 CAM60014.1 - 0.17 11.9 10.0 0.13 12.3 0.7 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1228) PT-VENN PF04829.8 CAM60014.1 - 4.1 7.0 6.9 1.4 8.5 0.2 2.5 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif Ribosomal_60s PF00428.14 CAM60016.1 - 0.008 16.5 0.2 0.053 13.9 0.0 1.9 2 0 0 2 2 2 1 60s Acidic ribosomal protein Ribosomal_60s PF00428.14 CAM60017.1 - 7.7e-20 71.0 12.2 9.3e-20 70.8 8.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein TLD PF07534.11 CAM60018.1 - 1.1e-16 61.1 0.0 2.9e-15 56.4 0.0 2.2 2 0 0 2 2 2 1 TLD HEM4 PF02602.10 CAM60019.1 - 1e-61 208.1 1.2 1.2e-61 207.9 0.8 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD DEAD PF00270.24 CAM60020.1 - 5.9e-20 71.4 0.0 5.5e-19 68.2 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM60020.1 - 0.00035 20.3 0.4 0.00075 19.3 0.3 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Beta_helix PF13229.1 CAM60021.2 - 0.0013 18.4 2.3 4.3 7.0 0.0 5.1 6 1 0 6 6 6 1 Right handed beta helix region Sigma70_ECF PF07638.6 CAM60021.2 - 0.19 11.3 0.1 1 8.9 0.0 2.0 2 0 0 2 2 2 0 ECF sigma factor tRNA_edit PF04073.10 CAM60022.1 - 1e-19 70.5 0.0 6.5e-19 67.9 0.0 2.0 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain COX17 PF05051.8 CAM60025.1 - 9.6e-20 70.3 6.5 1.2e-19 69.9 4.5 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Ndufs5 PF10200.4 CAM60025.1 - 0.47 10.4 2.9 0.66 10.0 2.0 1.4 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa TatD_DNase PF01026.16 CAM60026.1 - 1.9e-60 204.2 0.1 2.7e-60 203.7 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase LRR_4 PF12799.2 CAM60028.1 - 6.7e-11 41.5 9.1 0.00032 20.2 0.0 4.0 4 1 0 4 4 4 3 Leucine Rich repeats (2 copies) Ubiquitin_2 PF14560.1 CAM60028.1 - 3.5e-09 36.7 0.0 6.8e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain LRR_6 PF13516.1 CAM60028.1 - 1.3e-05 24.8 1.9 5.3 7.4 0.0 5.6 5 0 0 5 5 5 1 Leucine Rich repeat LRR_8 PF13855.1 CAM60028.1 - 2.1e-05 24.2 9.3 0.044 13.5 1.2 3.7 2 2 0 3 3 3 2 Leucine rich repeat LRR_9 PF14580.1 CAM60028.1 - 3e-05 23.6 0.6 0.9 9.0 0.0 3.6 3 1 0 3 3 3 2 Leucine-rich repeat LRR_7 PF13504.1 CAM60028.1 - 0.00071 19.3 15.5 1 9.8 0.3 6.3 6 0 0 6 6 6 1 Leucine rich repeat ubiquitin PF00240.18 CAM60028.1 - 0.0011 18.2 0.1 0.026 13.9 0.1 2.4 1 1 0 1 1 1 1 Ubiquitin family LRR_1 PF00560.28 CAM60028.1 - 0.0022 17.7 11.9 2.8 8.3 0.1 5.9 7 1 0 7 7 7 1 Leucine Rich Repeat Pkinase PF00069.20 CAM60029.1 - 9.5e-17 60.9 0.2 1.7e-13 50.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAM60029.1 - 0.00037 19.6 0.0 0.00066 18.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RNA_pol_Rpb4 PF03874.11 CAM60030.1 - 0.018 15.0 0.0 0.71 9.8 0.0 2.7 3 0 0 3 3 3 0 RNA polymerase Rpb4 6PF2K PF01591.13 CAM60031.1 - 5.7e-64 215.2 0.0 8.3e-64 214.6 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase Ank_2 PF12796.2 CAM60031.1 - 7.1e-15 55.1 0.2 1.7e-14 53.9 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CAM60031.1 - 5.7e-13 47.9 0.4 4.4e-08 32.5 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 CAM60031.1 - 4.6e-12 46.0 1.7 8.3e-09 35.7 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CAM60031.1 - 1.3e-10 41.1 4.0 2.9e-08 33.7 0.4 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CAM60031.1 - 1.9e-08 33.7 0.1 0.002 18.2 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat AAA_33 PF13671.1 CAM60031.1 - 2e-07 31.0 0.0 7.6e-07 29.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CAM60031.1 - 0.0037 18.0 0.0 0.007 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain USP7_C2 PF14533.1 CAM60031.1 - 1.8 7.9 0.0 3.6 6.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal DUF2217 PF10265.4 CAM60031.1 - 2.2 6.9 0.9 7.3 5.2 0.6 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF3800 PF12686.2 CAM60033.2 - 6.3 6.3 0.0 10 5.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3800) LRR_4 PF12799.2 CAM60036.1 - 1.2e-12 47.0 4.3 0.00014 21.3 0.2 4.3 2 2 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM60036.1 - 1.6e-07 30.9 9.5 0.00035 20.2 0.4 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 CAM60036.1 - 0.00016 21.2 9.8 9.7 6.6 0.0 6.1 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.1 CAM60036.1 - 0.0047 16.8 4.0 20 5.6 0.0 5.4 4 1 1 5 5 5 1 Leucine Rich repeat NIF PF03031.13 CAM60038.1 - 1.9e-27 95.8 0.0 1.6e-19 70.0 0.0 2.4 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase Brix PF04427.13 CAM60039.1 - 5.7e-43 146.8 0.1 8.5e-43 146.2 0.0 1.2 1 0 0 1 1 1 1 Brix domain Pyrophosphatase PF00719.14 CAM60040.1 - 1.4e-44 151.2 0.0 1.7e-44 151.0 0.0 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase Got1 PF04178.7 CAM60041.1 - 1.9e-29 102.1 20.1 2.8e-29 101.6 14.0 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Polysacc_synt_3 PF13440.1 CAM60041.1 - 0.96 8.8 16.5 0.32 10.4 7.7 2.0 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein Peptidase_U4 PF03419.8 CAM60041.1 - 2.6 7.0 11.7 3.3 6.6 8.1 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA SdpI PF13630.1 CAM60041.1 - 4.3 7.1 13.5 4.6 7.0 1.3 2.6 2 0 0 2 2 2 0 SdpI/YhfL protein family PalH PF08733.5 CAM60041.1 - 7.1 5.3 13.8 66 2.1 9.6 2.0 1 1 0 1 1 1 0 PalH/RIM21 Amidohydro_3 PF07969.6 CAM60042.1 - 1.9e-51 175.5 0.3 2.5e-26 92.8 3.0 2.3 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.15 CAM60042.1 - 2e-09 37.5 1.9 2.5e-05 24.0 0.0 3.0 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 CAM60042.1 - 2.3e-08 33.7 0.1 1.1e-07 31.5 0.0 2.3 2 1 0 2 2 2 1 Amidohydrolase CENP-W PF15510.1 CAM60043.1 - 0.041 13.8 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 Centromere kinetochore component W Cu-oxidase_2 PF07731.9 CAM60044.1 - 2e-17 63.0 2.7 2e-17 63.0 1.9 3.5 3 2 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 CAM60044.1 - 3.1e-10 39.8 7.0 6.5e-07 29.0 1.8 3.8 3 1 0 3 3 3 2 Multicopper oxidase MORN PF02493.15 CAM60046.1 - 3.1e-24 83.2 39.6 1.1e-06 28.0 1.2 7.2 7 1 0 7 7 7 6 MORN repeat EIF_2_alpha PF07541.7 CAM60047.1 - 1.2e-24 86.1 0.0 7.7e-23 80.3 0.0 2.2 1 1 1 2 2 2 2 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 CAM60047.1 - 2.9e-11 43.2 0.4 6.1e-11 42.2 0.3 1.6 1 0 0 1 1 1 1 S1 RNA binding domain EXOSC1 PF10447.4 CAM60047.1 - 0.0035 17.2 0.4 0.0076 16.1 0.3 1.6 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 E1-E2_ATPase PF00122.15 CAM65024.2 - 2.1e-65 219.9 1.6 2.1e-65 219.9 1.1 2.4 3 1 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CAM65024.2 - 1.4e-43 148.5 5.7 1.4e-43 148.5 4.0 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CAM65024.2 - 1.2e-30 107.5 0.1 8.8e-30 104.7 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CAM65024.2 - 6.6e-18 64.4 0.0 1.7e-17 63.1 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CAM65024.2 - 9.5e-14 50.6 0.0 2.6e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CAM65024.2 - 6.6e-13 49.2 0.1 2.6e-12 47.2 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CAM65024.2 - 2.3e-07 30.6 1.3 5.3e-06 26.1 0.5 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase BT1 PF03092.11 CAM65025.1 - 2.3e-76 257.2 12.0 2.8e-76 256.9 8.3 1.0 1 0 0 1 1 1 1 BT1 family PDEase_I PF00233.14 CAM65026.1 - 1.5e-10 41.2 0.2 2.6e-10 40.4 0.2 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Phosphoprotein PF00922.12 CAM65026.1 - 0.17 11.0 5.7 0.4 9.8 4.0 1.5 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein zf-C2H2_2 PF12756.2 CAM65029.1 - 1.6 8.8 7.4 0.063 13.4 0.9 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Topo_C_assoc PF14370.1 CAM65030.1 - 1e-28 98.7 0.4 1.5e-28 98.2 0.2 1.3 1 0 0 1 1 1 1 C-terminal topoisomerase domain BUD22 PF09073.5 CAM65030.1 - 0.0076 15.3 2.0 0.0093 15.0 1.4 1.2 1 0 0 1 1 1 1 BUD22 PCNP PF15473.1 CAM65030.1 - 0.092 13.0 4.9 0.052 13.8 1.7 1.9 2 0 0 2 2 2 0 PEST, proteolytic signal-containing nuclear protein family CDC45 PF02724.9 CAM65030.1 - 0.32 8.9 3.2 0.35 8.8 2.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.4 CAM65030.1 - 0.39 8.9 4.4 0.44 8.7 3.0 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF2217 PF10265.4 CAM65030.1 - 1.3 7.6 4.8 1.6 7.4 3.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) RAP1 PF07218.6 CAM65030.1 - 1.3 6.9 15.6 1.8 6.5 10.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AF-4 PF05110.8 CAM65030.1 - 3.1 5.5 24.3 4 5.1 16.8 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Methyltransf_18 PF12847.2 CAM65031.1 - 0.0027 18.2 0.0 0.0049 17.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAM65031.1 - 0.0038 17.5 0.0 0.0065 16.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAM65031.1 - 0.0088 15.6 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain BLOC1_2 PF10046.4 CAM65032.1 - 0.033 14.3 0.2 0.051 13.7 0.1 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Hemerythrin PF01814.18 CAM65032.1 - 0.066 13.3 1.9 0.099 12.7 1.3 1.3 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain DASH_Dam1 PF08653.5 CAM65032.1 - 0.074 12.8 0.2 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 DASH complex subunit Dam1 CorA PF01544.13 CAM65032.1 - 0.076 12.0 0.1 0.09 11.8 0.1 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Transposase_22 PF02994.9 CAM65032.1 - 0.078 11.4 0.1 0.086 11.3 0.1 1.2 1 0 0 1 1 1 0 L1 transposable element MIS13 PF08202.6 CAM65032.1 - 0.078 12.0 0.1 0.085 11.9 0.1 1.1 1 0 0 1 1 1 0 Mis12-Mtw1 protein family DUF2638 PF10937.3 CAM65034.1 - 0.049 14.6 1.1 0.15 13.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2638) DUF3584 PF12128.3 CAM65034.1 - 0.13 9.5 9.1 0.18 9.0 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) BRE1 PF08647.6 CAM65034.1 - 0.24 11.4 6.5 3.1 7.8 1.2 2.9 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase eIF3_N PF09440.5 CAM65034.1 - 0.26 11.4 2.9 0.43 10.7 0.1 2.1 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain Kinetocho_Slk19 PF12709.2 CAM65035.1 - 0.1 12.6 0.1 1.3 9.1 0.0 2.5 2 1 1 3 3 3 0 Central kinetochore-associated MAD PF05557.8 CAM65035.1 - 0.11 10.5 3.4 0.2 9.7 2.4 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein ERM PF00769.14 CAM65035.1 - 1.7 8.1 7.8 6.2 6.2 5.4 2.0 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Mnd1 PF03962.10 CAM65035.1 - 2.2 7.9 4.9 2.1 7.9 2.2 1.8 2 0 0 2 2 2 0 Mnd1 family HALZ PF02183.13 CAM65038.1 - 0.15 11.7 0.7 0.3 10.8 0.1 1.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper Defensin_propep PF00879.13 CAM65040.1 - 0.16 11.9 0.4 0.32 10.9 0.3 1.4 1 0 0 1 1 1 0 Defensin propeptide VSP PF03302.8 CAM65041.1 - 4.5e-06 25.5 159.5 0.0093 14.6 10.4 7.7 1 1 8 9 9 9 8 Giardia variant-specific surface protein VSP PF03302.8 CAM65042.1 - 0.00046 18.9 128.9 0.082 11.5 17.7 7.0 2 1 4 7 7 7 5 Giardia variant-specific surface protein VSP PF03302.8 CAM65043.1 - 0.02 13.5 23.7 0.1 11.1 3.4 2.3 1 1 1 2 2 2 0 Giardia variant-specific surface protein GBP_PSP PF02425.10 CAM65043.1 - 0.096 12.2 0.5 1.6 8.3 0.0 2.5 2 0 0 2 2 2 0 Paralytic/GBP/PSP peptide VSP PF03302.8 CAM65044.1 - 0.0051 15.5 43.2 0.019 13.6 3.4 4.0 1 1 3 4 4 4 3 Giardia variant-specific surface protein cEGF PF12662.2 CAM65044.1 - 7.9 6.2 22.8 6.8 6.4 1.8 5.2 4 2 0 4 4 4 0 Complement Clr-like EGF-like PIG-P PF08510.7 CAM65045.1 - 0.058 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 PIG-P Toprim_4 PF13662.1 CAM65045.1 - 0.16 11.9 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Toprim domain Orthoreo_P10 PF07204.6 CAM65046.1 - 0.011 15.5 0.1 0.021 14.5 0.1 1.4 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 TMEM52 PF14979.1 CAM65046.1 - 0.017 15.0 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 Transmembrane 52 GRAM PF02893.15 CAM65047.1 - 2.8e-05 23.5 0.0 6.6e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 GRAM domain PH_BEACH PF14844.1 CAM65047.1 - 0.12 12.2 0.0 2.1 8.2 0.0 2.3 2 0 0 2 2 2 0 PH domain associated with Beige/BEACH PseudoU_synth_2 PF00849.17 CAM65048.1 - 4e-41 140.5 0.0 7e-41 139.7 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase TPR_11 PF13414.1 CAM65049.1 - 1e-07 31.4 12.3 0.0092 15.6 0.1 3.6 3 1 1 4 4 4 3 TPR repeat TPR_2 PF07719.12 CAM65049.1 - 4e-06 26.3 11.3 0.0008 19.1 0.0 4.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 CAM65049.1 - 1.4e-05 24.4 8.3 0.00073 19.0 0.0 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 CAM65049.1 - 0.00011 21.9 0.2 0.00011 21.9 0.2 3.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 CAM65049.1 - 0.0016 18.3 0.6 0.0016 18.3 0.4 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 CAM65049.1 - 0.0042 16.7 1.6 0.12 12.1 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CAM65049.1 - 0.009 15.8 0.1 0.028 14.3 0.1 1.8 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat ATG16 PF08614.6 CAM65049.1 - 0.034 13.9 3.5 0.43 10.3 1.3 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) TPR_8 PF13181.1 CAM65049.1 - 0.32 10.8 2.1 3.2 7.7 0.0 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 CAM65049.1 - 4.3 8.1 21.5 0.41 11.3 2.7 4.7 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 CAM65049.1 - 6.8 7.3 10.1 5.5 7.6 0.1 3.9 4 1 0 4 4 4 0 Tetratricopeptide repeat MRP-L47 PF06984.8 CAM65050.1 - 4.1e-29 100.3 0.2 7.8e-29 99.4 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) A_deaminase PF00962.17 CAM65051.1 - 2.9e-80 269.6 0.2 2.4e-56 191.0 0.0 2.9 3 0 0 3 3 3 2 Adenosine/AMP deaminase ADH_N PF08240.7 CAM65052.1 - 2.4e-07 30.4 0.5 4.7e-07 29.5 0.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CAM65052.1 - 0.0002 20.9 0.0 0.00037 20.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF4164 PF13747.1 CAM65053.1 - 0.0036 17.3 0.8 0.0068 16.5 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4164) TRCF PF03461.10 CAM65053.1 - 0.073 13.0 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 TRCF domain Glyco_hydro_32N PF00251.15 CAM65054.1 - 1.1e-59 202.3 10.9 1.5e-59 201.9 7.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 CAM65054.1 - 7.8e-06 26.1 0.0 0.0027 18.0 0.0 2.6 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 C terminal PAN_1 PF00024.21 CAM65054.1 - 5e-05 22.9 0.6 0.00011 21.8 0.4 1.5 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.1 CAM65054.1 - 0.017 14.8 0.9 0.045 13.4 0.6 1.7 1 0 0 1 1 1 0 PAN domain Glyco_hydro_32N PF00251.15 CAM65055.1 - 2.3e-21 76.4 0.3 3.3e-21 75.9 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 CAM65055.1 - 3.4e-06 27.3 0.0 0.0018 18.6 0.0 2.7 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 C terminal PAN_1 PF00024.21 CAM65055.1 - 3.3e-05 23.5 0.6 7.4e-05 22.4 0.4 1.5 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.1 CAM65055.1 - 0.014 15.1 0.9 0.032 13.9 0.6 1.5 1 0 0 1 1 1 0 PAN domain RNB PF00773.14 CAM65056.1 - 1.9e-56 191.7 0.0 4.7e-56 190.4 0.0 1.6 2 0 0 2 2 2 1 RNB domain Arf PF00025.16 CAM65057.1 - 2.4e-54 183.2 0.0 2.8e-54 182.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CAM65057.1 - 5.1e-15 55.2 0.0 5.9e-15 55.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAM65057.1 - 3.3e-12 46.9 0.0 7.2e-12 45.8 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 CAM65057.1 - 1.1e-10 41.0 0.0 1.4e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CAM65057.1 - 1.3e-09 37.5 0.0 1.6e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 CAM65057.1 - 4.6e-08 32.1 0.5 7.2e-06 24.9 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 CAM65057.1 - 1.1e-06 28.5 0.0 1.6e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CAM65057.1 - 0.0077 15.6 0.0 0.021 14.2 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 CAM65057.1 - 0.0085 16.2 0.3 0.056 13.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CAM65057.1 - 0.03 14.6 0.0 0.074 13.3 0.0 1.6 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.7 CAM65057.1 - 0.069 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_21 PF13304.1 CAM65057.1 - 0.069 13.0 0.0 0.078 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Urocanase PF01175.13 CAM65057.1 - 0.077 11.0 0.0 0.095 10.7 0.0 1.1 1 0 0 1 1 1 0 Urocanase RED_C PF07807.6 CAM65059.1 - 0.0087 16.2 1.2 0.015 15.4 0.8 1.5 1 0 0 1 1 1 1 RED-like protein C-terminal region PhyH PF05721.8 CAM65060.1 - 5.8e-42 144.1 0.0 7.6e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF3243 PF11588.3 CAM65060.1 - 0.016 15.2 0.0 0.044 13.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3243) Shisa PF13908.1 CAM65061.1 - 8.5e-05 22.7 0.0 0.00017 21.8 0.0 1.5 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Epiglycanin_C PF14654.1 CAM65061.1 - 0.0014 18.5 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 Mucin, catalytic, TM and cytoplasmic tail region Herpes_gE PF02480.11 CAM65061.1 - 0.0082 14.4 0.1 0.011 13.9 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 CAM65061.1 - 0.015 15.6 0.0 0.04 14.3 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FAM163 PF15069.1 CAM65061.1 - 0.022 15.3 0.0 0.091 13.3 0.0 1.9 2 0 0 2 2 2 0 FAM163 family CcoS PF03597.10 CAM65061.1 - 0.041 13.3 1.5 0.046 13.1 0.0 1.8 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type TMEM52 PF14979.1 CAM65061.1 - 0.042 13.7 0.2 0.072 12.9 0.2 1.4 1 0 0 1 1 1 0 Transmembrane 52 MSC PF09402.5 CAM65061.1 - 0.043 12.5 0.0 0.055 12.1 0.0 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Plant_vir_prot PF01307.12 CAM65061.1 - 0.086 12.5 0.0 0.25 11.0 0.0 1.8 1 0 0 1 1 1 0 Plant viral movement protein APC10 PF03256.11 CAM65062.1 - 1.1e-77 260.0 0.0 7.9e-71 237.6 0.0 2.1 2 0 0 2 2 2 2 Anaphase-promoting complex, subunit 10 (APC10) TPR_1 PF00515.23 CAM65064.1 - 3.3e-10 39.1 3.6 0.00012 21.5 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 CAM65064.1 - 1.2e-08 34.4 8.6 0.00069 19.2 0.1 4.0 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.12 CAM65064.1 - 8.3e-08 31.5 2.7 1e-05 25.0 0.2 4.0 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CAM65064.1 - 1.5e-07 30.6 1.8 0.0003 20.3 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CAM65064.1 - 2.8e-06 27.4 2.3 0.00049 20.5 0.0 5.6 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 CAM65064.1 - 0.00035 20.4 14.7 0.039 13.8 2.4 4.4 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 CAM65064.1 - 0.0019 17.8 4.1 0.066 13.0 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 CAM65064.1 - 0.0046 17.3 0.1 1.9 9.1 0.0 3.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 CAM65064.1 - 0.006 16.4 6.8 0.77 9.6 0.3 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat SNAP PF14938.1 CAM65064.1 - 0.013 14.7 3.9 0.041 13.0 0.2 2.6 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP TipAS PF07739.8 CAM65064.1 - 0.11 12.8 3.5 0.23 11.7 0.1 2.8 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain Spore_SspJ PF09575.5 CAM65064.1 - 0.23 11.6 1.4 0.89 9.8 1.0 2.0 1 0 0 1 1 1 0 Small spore protein J (Spore_SspJ) TPR_19 PF14559.1 CAM65064.1 - 0.24 11.7 0.1 0.24 11.7 0.1 4.7 4 2 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 CAM65064.1 - 1.5 9.6 25.3 1.6 9.5 0.5 5.4 4 1 2 6 6 5 0 Tetratricopeptide repeat TPR_21 PF09976.4 CAM65064.1 - 6.5 6.6 21.3 0.41 10.5 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat RAP1 PF07218.6 CAM65065.1 - 4.9 5.1 4.1 8.1 4.4 2.8 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pkinase PF00069.20 CAM65066.1 - 3.7e-43 147.5 0.0 1.5e-35 122.6 0.0 4.2 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CAM65066.1 - 7.2e-33 113.7 0.0 2.9e-16 59.3 0.0 4.3 4 0 0 4 4 4 4 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CAM65066.1 - 0.87 8.3 0.0 1.3 7.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Peptidase_C2 PF00648.16 CAM65067.1 - 2.5e-48 164.6 0.0 3.6e-48 164.0 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 CAM65067.1 - 2.9e-35 120.3 0.0 7e-35 119.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Lyase_1 PF00206.15 CAM65068.1 - 1.9e-48 165.2 0.0 2.5e-48 164.8 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C PF08328.6 CAM65068.1 - 2.1e-45 153.2 0.0 3.6e-45 152.4 0.0 1.4 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal Ribosomal_L5_C PF00673.16 CAM65070.1 - 3.2e-22 78.0 0.0 5.5e-22 77.3 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 CAM65070.1 - 8.9e-17 60.6 0.4 3.2e-16 58.8 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L5 Arf PF00025.16 CAM65071.1 - 3.2e-61 205.5 0.0 3.7e-61 205.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CAM65071.1 - 3.5e-14 52.4 0.0 4.3e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CAM65071.1 - 1.4e-11 44.0 0.0 1.7e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CAM65071.1 - 3.3e-11 42.5 0.2 1.4e-09 37.1 0.0 2.3 1 1 1 2 2 2 1 G-protein alpha subunit Miro PF08477.8 CAM65071.1 - 1.1e-07 32.3 0.0 1.5e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 CAM65071.1 - 3.7e-07 29.5 0.0 4.4e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CAM65071.1 - 0.00011 22.1 0.0 0.00014 21.7 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 CAM65071.1 - 0.00032 19.8 0.0 0.00044 19.3 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 CAM65071.1 - 0.0019 17.6 0.0 0.025 13.9 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain NACHT PF05729.7 CAM65071.1 - 0.0082 15.8 0.1 0.072 12.7 0.1 2.0 1 1 0 1 1 1 1 NACHT domain AAA_33 PF13671.1 CAM65071.1 - 0.033 14.0 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CAM65071.1 - 0.056 12.5 0.0 0.083 11.9 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin NTP_transf_2 PF01909.18 CAM65073.1 - 1.9e-06 28.0 0.0 3.6e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 CAM65073.1 - 0.00015 21.5 0.1 0.0003 20.6 0.1 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase DUF2852 PF11014.3 CAM65073.1 - 0.26 11.2 0.2 1.2 9.1 0.1 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) Ank_2 PF12796.2 CAM65075.1 - 4.5e-27 94.2 1.0 2.2e-13 50.3 0.1 4.3 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CAM65075.1 - 1.6e-23 82.6 2.7 2.4e-08 34.2 0.0 5.9 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 CAM65075.1 - 7.9e-22 76.7 7.4 1.4e-11 44.1 0.0 5.7 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.25 CAM65075.1 - 8.3e-20 69.5 19.8 2.5e-09 36.4 0.0 6.3 7 1 0 7 7 7 3 Ankyrin repeat Ank_3 PF13606.1 CAM65075.1 - 2.6e-18 64.2 5.0 7.8e-05 22.5 0.0 6.6 6 0 0 6 6 6 4 Ankyrin repeat zf-DHHC PF01529.15 CAM65075.1 - 3.6e-14 52.5 0.0 3.6e-14 52.5 0.0 2.0 2 1 1 3 3 3 1 DHHC palmitoyltransferase HisKA_3 PF07730.8 CAM65076.1 - 2 8.7 8.1 0.23 11.8 1.1 2.7 2 1 1 3 3 3 0 Histidine kinase EF-hand_7 PF13499.1 CAM65077.1 - 1.1e-06 28.6 0.0 0.0019 18.3 0.0 2.6 1 1 2 3 3 3 2 EF-hand domain pair zf-C3HC4_2 PF13923.1 CAM65077.1 - 1.5e-06 28.1 6.6 4.6e-06 26.5 4.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CAM65077.1 - 3.4e-06 26.7 7.0 1.2e-05 24.9 4.8 2.0 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CAM65077.1 - 4.4e-06 26.3 4.9 1.2e-05 24.9 3.4 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CAM65077.1 - 1.9e-05 24.2 5.5 4.9e-05 22.9 3.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CAM65077.1 - 2.4e-05 24.0 6.8 2.4e-05 24.0 4.7 2.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING EF-hand_6 PF13405.1 CAM65077.1 - 3.4e-05 23.3 0.0 2.7 8.1 0.0 4.2 4 0 0 4 4 4 1 EF-hand domain zf-C3HC4_3 PF13920.1 CAM65077.1 - 0.00059 19.4 4.5 0.00059 19.4 3.1 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) EF-hand_1 PF00036.27 CAM65077.1 - 0.0049 16.0 0.0 7.8 6.0 0.0 3.5 4 0 0 4 4 3 1 EF hand EF-hand_8 PF13833.1 CAM65077.1 - 0.029 13.9 0.0 0.2 11.2 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair zf-CHY PF05495.7 CAM65077.1 - 0.032 14.3 1.6 0.032 14.3 1.1 2.5 1 1 2 3 3 3 0 CHY zinc finger Rad50_zn_hook PF04423.9 CAM65077.1 - 0.062 12.7 1.0 0.25 10.8 0.0 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_6 PF14835.1 CAM65077.1 - 0.11 12.3 2.5 0.32 10.8 1.7 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Elf1 PF05129.8 CAM65077.1 - 2.2 8.0 6.9 3 7.6 1.6 2.4 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like DnaJ_CXXCXGXG PF00684.14 CAM65077.1 - 4.5 7.3 8.7 22 5.1 1.2 2.8 1 1 2 3 3 3 0 DnaJ central domain TPR_19 PF14559.1 CAM65078.1 - 1.7e-35 121.1 56.7 6.4e-06 26.4 0.2 15.2 8 4 7 15 15 15 10 Tetratricopeptide repeat TPR_2 PF07719.12 CAM65078.1 - 7.1e-30 100.5 44.6 0.0034 17.1 0.1 20.0 21 0 0 21 21 21 6 Tetratricopeptide repeat TPR_11 PF13414.1 CAM65078.1 - 1.6e-29 101.2 49.3 1.8e-06 27.4 0.0 14.3 10 5 9 19 19 19 11 TPR repeat TPR_16 PF13432.1 CAM65078.1 - 1.7e-26 92.2 85.3 3.9e-07 30.5 2.9 16.0 12 5 6 19 19 17 7 Tetratricopeptide repeat TPR_14 PF13428.1 CAM65078.1 - 6.4e-23 79.1 95.8 0.0004 20.7 0.1 22.6 11 7 13 24 24 23 7 Tetratricopeptide repeat TPR_1 PF00515.23 CAM65078.1 - 1.7e-22 78.0 25.6 0.0011 18.5 0.2 14.1 16 0 0 16 16 15 6 Tetratricopeptide repeat TPR_12 PF13424.1 CAM65078.1 - 9.2e-21 73.5 51.4 0.00076 19.3 1.1 15.1 12 5 4 17 17 17 6 Tetratricopeptide repeat TPR_17 PF13431.1 CAM65078.1 - 3.7e-15 54.7 13.3 1.4 9.3 0.0 13.8 14 0 0 14 14 13 2 Tetratricopeptide repeat TPR_8 PF13181.1 CAM65078.1 - 2.4e-14 51.9 9.0 0.24 11.2 0.1 10.9 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_7 PF13176.1 CAM65078.1 - 4.8e-12 44.7 32.4 0.16 11.8 0.0 13.5 15 0 0 15 15 13 4 Tetratricopeptide repeat Apc3 PF12895.2 CAM65078.1 - 6.3e-12 45.4 37.2 0.05 13.7 0.6 10.4 9 3 3 12 12 11 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 CAM65078.1 - 5.8e-08 32.4 46.1 0.04 14.3 0.2 14.1 14 0 0 14 14 12 3 Tetratricopeptide repeat TPR_6 PF13174.1 CAM65078.1 - 1.1e-06 28.7 64.4 0.15 12.5 0.0 19.6 23 0 0 23 23 21 2 Tetratricopeptide repeat NARP1 PF12569.3 CAM65078.1 - 3.6e-05 22.7 4.1 0.47 9.1 0.1 4.9 4 1 1 5 5 5 3 NMDA receptor-regulated protein 1 ChAPs PF09295.5 CAM65078.1 - 0.03 13.0 0.4 0.64 8.7 0.0 2.6 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) PPR PF01535.15 CAM65078.1 - 0.032 14.1 2.6 4.3 7.5 0.0 5.6 7 0 0 7 7 4 0 PPR repeat MIT PF04212.13 CAM65078.1 - 0.096 12.5 13.8 7 6.6 0.1 5.9 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain Y_phosphatase2 PF03162.8 CAM65079.1 - 1e-51 174.6 0.0 1.3e-51 174.2 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 CAM65079.1 - 1.4e-08 35.1 0.0 3.1e-08 34.0 0.0 1.5 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 CAM65079.1 - 0.0054 16.1 0.0 0.0076 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 CAM65079.1 - 0.032 13.8 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 CAM65079.1 - 0.074 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate DENN PF02141.16 CAM65080.2 - 4e-10 39.7 1.3 1.1e-09 38.2 0.9 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain Pox_P4A PF03395.9 CAM65080.2 - 0.99 6.8 0.0 1.4 6.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus P4A protein Spermine_synth PF01564.12 CAM65081.1 - 1.2e-66 224.1 0.0 1.5e-66 223.8 0.0 1.0 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 CAM65081.1 - 0.0024 17.8 0.0 0.0056 16.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAM65081.1 - 0.021 15.3 0.0 0.077 13.4 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Laminin_I PF06008.9 CAM65082.1 - 0.013 14.7 0.3 0.018 14.3 0.2 1.2 1 0 0 1 1 1 0 Laminin Domain I NPDC1 PF06809.6 CAM65082.1 - 0.068 11.9 1.2 0.1 11.3 0.2 1.6 1 1 1 2 2 2 0 Neural proliferation differentiation control-1 protein (NPDC1) Glyco_trans_1_2 PF13524.1 CAM65082.1 - 0.079 13.2 2.4 0.14 12.4 1.0 1.9 1 1 0 1 1 1 0 Glycosyl transferases group 1 Ank_2 PF12796.2 CAM65083.1 - 5e-21 74.8 0.4 1e-05 25.7 0.1 5.1 4 0 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CAM65083.1 - 1.8e-15 56.9 4.7 0.00055 20.3 0.0 6.0 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 CAM65083.1 - 6.9e-15 54.7 14.5 8.1e-05 22.7 0.1 6.5 7 0 0 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.25 CAM65083.1 - 7.5e-15 53.9 11.3 0.0006 19.4 0.1 6.6 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.1 CAM65083.1 - 1e-09 37.6 3.6 0.042 14.0 0.0 5.5 5 0 0 5 5 5 2 Ankyrin repeat MRAP PF15183.1 CAM65083.1 - 0.93 9.1 0.2 2.4 7.8 0.1 1.6 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family DUF1168 PF06658.7 CAM65084.1 - 0.01 15.3 15.3 0.013 14.9 10.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Cwf_Cwc_15 PF04889.7 CAM65084.1 - 0.038 13.7 14.0 0.045 13.4 9.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Cu-oxidase_4 PF02578.10 CAM65084.1 - 0.043 12.9 0.5 0.054 12.5 0.4 1.1 1 0 0 1 1 1 0 Multi-copper polyphenol oxidoreductase laccase U1snRNP70_N PF12220.3 CAM65084.1 - 0.086 13.1 7.3 0.44 10.9 4.4 2.1 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Vir_act_alpha_C PF10400.4 CAM65084.1 - 0.15 12.4 7.0 0.29 11.5 4.4 1.9 1 1 0 1 1 1 0 Virulence activator alpha C-term DUF4603 PF15376.1 CAM65084.1 - 0.2 8.8 11.5 0.23 8.5 8.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) ECM11 PF15463.1 CAM65085.1 - 0.0041 17.4 0.6 0.0041 17.4 0.4 2.3 2 0 0 2 2 2 1 Extracellular mutant protein 11 HCNGP PF07818.8 CAM65087.1 - 0.018 15.0 0.1 0.028 14.4 0.1 1.3 1 0 0 1 1 1 0 HCNGP-like protein Y1_Tnp PF01797.11 CAM65087.1 - 0.021 14.6 0.3 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 Transposase IS200 like TFIID-18kDa PF02269.11 CAM65087.1 - 0.036 13.8 0.5 0.072 12.9 0.3 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit DUF600 PF04634.7 CAM65087.1 - 0.046 13.7 1.4 0.081 12.9 0.5 1.7 1 1 1 2 2 2 0 Protein of unknown function, DUF600 zf-C3HC4_3 PF13920.1 CAM65088.1 - 4.9e-09 35.7 8.6 8.9e-09 34.8 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CAM65088.1 - 1.6e-07 30.8 9.2 2.8e-07 30.0 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAM65088.1 - 2.1e-06 27.6 12.1 3.8e-06 26.8 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CAM65088.1 - 4.1e-05 23.3 13.1 8.2e-05 22.3 9.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CAM65088.1 - 0.0011 18.6 9.9 0.0025 17.5 6.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain TMEM154 PF15102.1 CAM65088.1 - 0.018 14.7 0.0 0.04 13.6 0.0 1.7 2 0 0 2 2 2 0 TMEM154 protein family zf-C3HC4_4 PF15227.1 CAM65088.1 - 0.069 13.0 10.8 0.18 11.7 7.5 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DAP10 PF07213.6 CAM65088.1 - 0.08 12.7 1.2 0.52 10.0 0.1 2.5 2 0 0 2 2 2 0 DAP10 membrane protein Baculo_IE-1 PF05290.6 CAM65088.1 - 0.29 10.8 4.3 0.62 9.7 3.0 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.1 CAM65088.1 - 0.76 9.4 8.1 1.6 8.4 5.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Pkinase PF00069.20 CAM65089.1 - 7e-40 136.8 0.5 5.8e-24 84.6 0.1 6.0 5 1 0 5 5 5 4 Protein kinase domain Pkinase_Tyr PF07714.12 CAM65089.1 - 9e-13 47.8 0.0 5.3e-08 32.2 0.1 4.0 4 0 0 4 4 4 2 Protein tyrosine kinase FHA PF00498.21 CAM65089.1 - 4.6e-10 39.4 0.0 2.7e-09 37.0 0.0 2.1 1 1 0 1 1 1 1 FHA domain TGS PF02824.16 CAM65089.1 - 0.037 13.8 0.0 0.13 12.0 0.0 2.0 1 0 0 1 1 1 0 TGS domain DUF2076 PF09849.4 CAM65090.1 - 1.3e-06 28.6 1.0 1.4e-06 28.6 0.7 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 CAM65090.1 - 3.7e-05 23.5 1.2 5.4e-05 22.9 0.8 1.3 1 0 0 1 1 1 1 CHCH domain DUF2076 PF09849.4 CAM65091.1 - 2.9e-07 30.8 3.6 3.2e-07 30.6 2.5 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 CAM65091.1 - 4.5e-05 23.2 1.2 6.2e-05 22.7 0.8 1.2 1 0 0 1 1 1 1 CHCH domain UQ_con PF00179.21 CAM65092.1 - 7.1e-46 155.1 0.1 8e-46 154.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CAM65092.1 - 0.00043 20.0 0.0 0.00055 19.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 CAM65092.1 - 0.0049 16.5 0.2 0.011 15.3 0.1 1.6 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 CAM65092.1 - 0.045 13.6 0.6 0.055 13.3 0.4 1.5 1 1 0 1 1 1 0 RWD domain Ax_dynein_light PF10211.4 CAM65093.1 - 8.8e-10 38.7 2.9 8.8e-10 38.7 2.0 2.7 3 0 0 3 3 3 1 Axonemal dynein light chain AcylCoA_dehyd_C PF12186.3 CAM65093.1 - 0.44 10.4 3.2 0.27 11.0 0.6 1.8 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase C terminal GAS PF13851.1 CAM65093.1 - 2 7.5 6.8 0.8 8.8 0.3 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding CesT PF05932.8 CAM65095.1 - 1.8e-09 37.4 0.1 4.5e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Tir chaperone protein (CesT) family PDZ_2 PF13180.1 CAM65095.1 - 6.6e-09 35.5 0.0 2.7e-06 27.1 0.1 2.5 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.19 CAM65095.1 - 0.031 14.4 0.0 1.1 9.4 0.0 2.6 2 0 0 2 2 2 0 PDZ domain (Also known as DHR or GLGF) PDZ_1 PF12812.2 CAM65095.1 - 0.15 11.9 0.0 0.43 10.4 0.0 1.8 1 0 0 1 1 1 0 PDZ-like domain DUF737 PF05300.6 CAM65095.1 - 6.6 6.6 34.3 3.7 7.4 13.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF737) DUF974 PF06159.8 CAM65097.1 - 1.4e-09 37.7 0.0 2.9e-09 36.7 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF974) Ribosomal_L16 PF00252.13 CAM65099.1 - 3.4e-27 94.8 0.3 4.3e-27 94.4 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e NAC PF01849.13 CAM65100.1 - 2.3e-18 65.4 0.7 3.5e-18 64.8 0.0 1.6 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 CAM65100.1 - 0.0026 17.5 2.2 0.0061 16.3 0.1 2.3 2 0 0 2 2 2 1 UBA/TS-N domain NCD2 PF04905.8 CAM65100.1 - 0.056 13.2 0.3 0.056 13.2 0.2 2.0 2 0 0 2 2 2 0 NAB conserved region 2 (NCD2) NAC PF01849.13 CAM65101.1 - 8.5e-19 66.8 0.8 1.6e-18 65.9 0.0 1.8 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 CAM65101.1 - 0.0014 18.3 0.2 0.0031 17.2 0.2 1.7 1 0 0 1 1 1 1 UBA/TS-N domain 3HBOH PF10605.4 CAM65101.1 - 0.078 11.0 5.9 0.16 10.0 4.1 1.6 1 1 0 1 1 1 0 3HB-oligomer hydrolase (3HBOH) NCD2 PF04905.8 CAM65101.1 - 0.55 10.0 4.0 0.29 10.9 0.2 2.0 2 0 0 2 2 2 0 NAB conserved region 2 (NCD2) Myc_N PF01056.13 CAM65101.1 - 0.56 9.3 6.1 0.75 8.8 4.2 1.4 1 1 0 1 1 1 0 Myc amino-terminal region DnaJ PF00226.26 CAM65103.1 - 3.5e-19 68.2 0.2 5.3e-19 67.7 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Pep_deformylase PF01327.16 CAM65107.1 - 1.4e-26 92.7 0.0 2.1e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 Polypeptide deformylase DUF1523 PF07509.6 CAM65107.1 - 0.097 11.8 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1523) Y_phosphatase2 PF03162.8 CAM65109.1 - 2.6e-55 186.2 0.0 3.4e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 CAM65109.1 - 0.0016 18.6 0.0 0.0029 17.8 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Rhomboid PF01694.17 CAM65110.1 - 4.9e-06 26.6 3.7 4.9e-06 26.6 2.6 2.0 2 1 0 2 2 2 1 Rhomboid family Ribosomal_L30 PF00327.15 CAM65111.1 - 0.00014 21.3 0.1 0.00067 19.1 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Tox-HNH-EHHH PF15657.1 CAM65113.1 - 0.081 13.0 0.6 1.7 8.8 0.0 2.4 2 0 0 2 2 2 0 HNH/Endo VII superfamily nuclease toxins Cmc1 PF08583.5 CAM65114.1 - 1.5e-05 24.7 1.3 2.1e-05 24.2 0.9 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.4 CAM65114.1 - 0.015 15.2 1.2 0.024 14.6 0.8 1.4 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa TPR_12 PF13424.1 CAM65116.1 - 3.5e-06 26.8 1.7 0.068 13.1 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 CAM65116.1 - 5.1e-05 22.7 0.0 0.0014 18.2 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 CAM65116.1 - 0.0096 15.7 0.2 0.039 13.8 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 CAM65116.1 - 0.012 15.1 0.7 0.031 13.8 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat IQ PF00612.22 CAM65116.1 - 0.048 13.3 0.1 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif TPR_11 PF13414.1 CAM65116.1 - 0.06 12.9 0.4 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 TPR repeat CaMBD PF02888.11 CAM65116.1 - 0.4 10.5 3.2 0.73 9.6 0.5 2.5 2 0 0 2 2 2 0 Calmodulin binding domain HpaP PF09483.5 CAM65117.1 - 0.031 14.2 2.6 0.038 13.9 1.8 1.2 1 0 0 1 1 1 0 Type III secretion protein (HpaP) CTDII PF01556.13 CAM65119.1 - 5.1e-28 96.7 3.3 2e-21 75.6 0.1 3.3 3 0 0 3 3 3 3 DnaJ C terminal domain DnaJ PF00226.26 CAM65119.1 - 1.2e-22 79.4 0.6 3.9e-22 77.7 0.5 1.8 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 CAM65119.1 - 2.2e-08 33.9 26.1 4.1e-08 33.1 18.1 1.5 1 0 0 1 1 1 1 DnaJ central domain Ribosomal_L16 PF00252.13 CAM65120.1 - 3.4e-27 94.8 0.3 4.3e-27 94.4 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e ADK PF00406.17 CAM65121.1 - 5.8e-39 133.3 0.0 7e-39 133.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_33 PF13671.1 CAM65121.1 - 9.7e-08 31.9 0.0 1.8e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CAM65121.1 - 1.1e-07 32.2 0.0 1.8e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CAM65121.1 - 1e-05 26.3 0.1 1.9e-05 25.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CAM65121.1 - 0.044 13.7 0.0 0.091 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 CAM65121.1 - 0.045 13.1 0.0 1.2 8.5 0.0 2.3 2 1 0 2 2 2 0 Thymidylate kinase Nop14 PF04147.7 CAM65125.1 - 3.7e-05 21.8 23.5 4.8e-05 21.5 16.3 1.1 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 CAM65125.1 - 0.00049 18.2 14.7 0.0006 17.9 10.2 1.2 1 0 0 1 1 1 1 CDC45-like protein YL1 PF05764.8 CAM65125.1 - 0.0011 18.6 17.0 0.0014 18.2 11.8 1.3 1 0 0 1 1 1 1 YL1 nuclear protein BUD22 PF09073.5 CAM65125.1 - 0.0046 16.0 20.0 0.0065 15.6 13.8 1.2 1 0 0 1 1 1 1 BUD22 SDA1 PF05285.7 CAM65125.1 - 0.0074 15.6 25.6 0.01 15.1 17.8 1.2 1 0 0 1 1 1 1 SDA1 Daxx PF03344.10 CAM65125.1 - 0.01 14.3 18.4 0.012 14.0 12.8 1.2 1 0 0 1 1 1 0 Daxx Family Cwf_Cwc_15 PF04889.7 CAM65125.1 - 0.41 10.3 22.6 0.12 12.0 13.6 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RRN3 PF05327.6 CAM65125.1 - 0.54 8.3 12.7 0.8 7.7 8.8 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF1510 PF07423.6 CAM65125.1 - 0.61 9.4 19.8 0.89 8.8 13.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Astro_capsid PF03115.9 CAM65125.1 - 1.3 7.2 7.2 1.3 7.1 5.0 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor TFIIF_alpha PF05793.7 CAM65125.1 - 3.3 5.9 23.8 5 5.3 16.5 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SAPS PF04499.10 CAM65125.1 - 4.5 5.8 7.7 6 5.3 5.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2201_N PF13203.1 CAM65125.1 - 5.8 6.0 10.7 3.3 6.7 6.4 1.4 1 1 0 1 1 1 0 Putative metallopeptidase domain Voltage_CLC PF00654.15 CAM65126.1 - 1.7e-85 287.1 29.0 1.7e-85 287.1 20.1 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 CAM65126.1 - 7e-09 35.3 2.3 0.00051 19.7 0.0 3.6 3 0 0 3 3 3 2 CBS domain TAT_signal PF10518.4 CAM65126.1 - 0.02 14.8 0.1 0.02 14.8 0.0 4.9 3 0 0 3 3 3 0 TAT (twin-arginine translocation) pathway signal sequence DUF947 PF06102.7 CAM65127.1 - 1.3e-17 64.1 10.7 3.7e-17 62.6 7.4 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF947) COPI_assoc PF08507.5 CAM65128.1 - 4.5e-13 49.0 7.7 6.2e-13 48.6 5.3 1.2 1 0 0 1 1 1 1 COPI associated protein Neurensin PF14927.1 CAM65128.1 - 0.046 13.1 6.7 13 5.1 4.6 2.4 1 1 0 1 1 1 0 Neurensin HemY_N PF07219.8 CAM65128.1 - 0.077 12.5 5.7 0.84 9.2 0.0 2.2 2 0 0 2 2 2 0 HemY protein N-terminus DUF1218 PF06749.7 CAM65128.1 - 0.11 12.9 0.6 0.11 12.9 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) DUF3357 PF11837.3 CAM65128.1 - 0.62 9.9 3.0 7.6 6.4 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) Acyltransferase PF01553.16 CAM65129.1 - 2.4e-11 43.1 0.0 4.3e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransferase PF01553.16 CAM65130.1 - 3.7e-12 45.8 0.0 5.5e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF4386 PF14329.1 CAM65130.1 - 0.1 12.0 1.1 0.16 11.3 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4386) Macoilin PF09726.4 CAM65131.1 - 0.094 10.9 0.0 0.094 10.9 0.0 1.5 2 0 0 2 2 2 0 Transmembrane protein FliG_C PF01706.11 CAM65132.1 - 0.097 12.6 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 FliG C-terminal domain Tcf25 PF04910.9 CAM65133.1 - 4.4e-67 226.5 0.0 9.8e-67 225.4 0.0 1.5 2 0 0 2 2 2 1 Transcriptional repressor TCF25 DUF3292 PF11696.3 CAM65133.1 - 3.3 5.4 5.9 4.9 4.8 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Kinesin PF00225.18 CAM65134.2 - 6.5e-83 278.2 0.0 7.7e-83 277.9 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain GTP_EFTU PF00009.22 CAM65134.2 - 0.035 13.5 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain BTV_NS2 PF04514.7 CAM65136.1 - 0.051 12.4 0.6 0.056 12.3 0.4 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FCH PF00611.18 CAM65136.1 - 0.069 13.3 0.7 0.15 12.2 0.5 1.8 1 1 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain E1-E2_ATPase PF00122.15 CAM65137.1 - 2.6e-20 72.4 0.4 5.2e-20 71.4 0.3 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CAM65137.1 - 5.8e-18 66.0 0.0 1.3e-17 64.9 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CAM65137.1 - 3.9e-05 23.8 0.0 7.1e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AAA_13 PF13166.1 CAM65138.1 - 4 5.7 16.9 6.1 5.1 11.7 1.1 1 0 0 1 1 1 0 AAA domain SCO1-SenC PF02630.9 CAM65139.1 - 2.3e-41 141.3 0.0 3.1e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 CAM65139.1 - 0.0061 16.2 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family FBPase PF00316.15 CAM65142.1 - 1.9e-109 365.4 0.0 2.4e-109 365.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase DUF3733 PF12534.3 CAM65142.1 - 0.056 12.7 0.1 0.31 10.3 0.1 2.0 2 0 0 2 2 2 0 Leucine-rich repeat containing protein 8 RRM_5 PF13893.1 CAM65144.1 - 4.2e-22 77.7 0.1 7.7e-10 38.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAM65144.1 - 3.1e-13 49.1 0.0 1.8e-05 24.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM65144.1 - 1e-12 47.8 0.0 3.3e-07 30.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CDC48_2 PF02933.12 CAM65144.1 - 0.00033 20.2 0.0 0.0007 19.1 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Calcipressin PF04847.7 CAM65144.1 - 0.0099 15.4 0.5 0.25 10.8 0.1 2.3 2 0 0 2 2 2 1 Calcipressin PAT1 PF09770.4 CAM65144.1 - 3.5 5.7 12.9 4.4 5.4 9.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PolyA_pol PF01743.15 CAM65146.1 - 8.8e-29 100.2 0.0 1.5e-28 99.4 0.0 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 CAM65146.1 - 2.6e-07 30.1 0.0 5.5e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Exosortase_EpsH PF09721.5 CAM65146.1 - 0.019 14.2 0.0 0.036 13.2 0.0 1.4 1 0 0 1 1 1 0 Transmembrane exosortase (Exosortase_EpsH) LRR_6 PF13516.1 CAM65147.1 - 9.5e-07 28.2 0.0 1.4 9.2 0.0 3.6 3 0 0 3 3 3 3 Leucine Rich repeat LRR_4 PF12799.2 CAM65147.1 - 2.1e-06 27.1 0.1 0.00044 19.7 0.2 3.2 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM65147.1 - 0.008 15.9 0.2 0.29 10.9 0.1 2.7 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 CAM65147.1 - 0.018 15.0 0.0 17 5.9 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich Repeat Pkinase PF00069.20 CAM65148.1 - 1e-31 110.0 0.0 1.3e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM65148.1 - 1.2e-17 63.8 0.1 1.8e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CAM65148.1 - 0.034 13.2 0.0 0.05 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Actin PF00022.14 CAM65150.1 - 4.3e-149 496.2 0.0 5e-149 496.0 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 CAM65150.1 - 0.013 15.9 0.1 0.065 13.6 0.0 2.0 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Pescadillo_N PF06732.6 CAM65151.2 - 8.4e-12 44.9 0.0 8.4e-12 44.9 0.0 2.0 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 CAM65151.2 - 5e-08 32.9 0.0 1.4e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain TilS PF09179.6 CAM65151.2 - 0.12 12.4 3.5 0.26 11.3 2.4 1.5 1 0 0 1 1 1 0 TilS substrate binding domain DUF2946 PF11162.3 CAM65152.1 - 4.5e-17 62.3 1.0 8.2e-17 61.5 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2946) Rhabdo_glycop PF00974.13 CAM65152.1 - 8.6e-05 20.9 0.7 0.00013 20.3 0.5 1.2 1 0 0 1 1 1 1 Rhabdovirus spike glycoprotein Shisa PF13908.1 CAM65152.1 - 0.0014 18.7 0.0 0.0032 17.6 0.0 1.6 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator RCR PF12273.3 CAM65152.1 - 0.0066 16.9 0.0 0.017 15.6 0.0 1.7 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Herpes_gE PF02480.11 CAM65152.1 - 0.0082 14.4 0.0 0.013 13.8 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Hum_adeno_E3A PF05393.6 CAM65152.1 - 0.067 12.8 1.5 0.17 11.5 1.0 1.7 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein EphA2_TM PF14575.1 CAM65152.1 - 0.094 13.1 0.4 0.26 11.6 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 CAM65152.1 - 0.23 11.1 0.5 0.46 10.1 0.1 1.6 2 0 0 2 2 2 0 TMEM154 protein family Tweety PF04906.8 CAM65152.1 - 0.3 9.4 4.4 0.19 10.1 0.3 2.0 2 0 0 2 2 2 0 Tweety Exo_endo_phos PF03372.18 CAM65153.1 - 1e-10 42.0 0.4 1.6e-10 41.3 0.3 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Kinesin PF00225.18 CAM65154.1 - 9.8e-95 317.0 0.0 1.3e-94 316.7 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain SAM_1 PF00536.25 CAM65154.1 - 0.064 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) CPSase_L_D2 PF02786.12 CAM65156.1 - 6.5e-77 257.5 0.5 1.4e-76 256.5 0.4 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CAM65156.1 - 7.3e-40 135.5 0.7 3.1e-39 133.4 0.0 2.2 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CAM65156.1 - 2.3e-34 117.5 0.0 6.5e-34 116.1 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 CAM65156.1 - 4.8e-18 64.5 4.5 4.9e-18 64.5 1.7 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 CAM65156.1 - 1.4e-13 50.9 0.1 3.6e-13 49.6 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CAM65156.1 - 3.3e-10 39.2 0.5 5.1e-10 38.6 0.4 1.2 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 CAM65156.1 - 1.9e-08 33.8 0.6 7.1e-08 31.9 0.2 2.0 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 CAM65156.1 - 2.7e-08 33.3 0.6 1.5e-05 24.5 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 CAM65156.1 - 2.2e-06 27.2 0.3 5.2e-06 25.9 0.2 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 CAM65156.1 - 0.0002 21.2 0.2 0.00036 20.4 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 CAM65156.1 - 0.00044 20.5 1.3 0.0091 16.3 0.3 2.7 2 1 1 3 3 2 1 HlyD family secretion protein ATPgrasp_ST PF14397.1 CAM65156.1 - 0.0019 17.3 0.0 0.0039 16.3 0.0 1.5 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp GARS_A PF01071.14 CAM65156.1 - 0.0038 16.8 0.0 0.0069 15.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GCV_H PF01597.14 CAM65156.1 - 0.018 14.7 0.5 0.044 13.4 0.3 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein GAS PF13851.1 CAM65157.1 - 0.0098 15.1 2.7 0.015 14.4 1.8 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF3958 PF13125.1 CAM65157.1 - 0.027 14.3 0.6 0.039 13.8 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) DUF1003 PF06210.6 CAM65157.1 - 0.09 12.7 2.7 8.8 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) YjbE PF11106.3 CAM65157.1 - 2.8 7.9 11.9 6.8 6.7 0.4 2.2 2 0 0 2 2 2 0 Exopolysaccharide production protein YjbE BSD PF03909.12 CAM65158.1 - 4.4e-11 42.3 0.0 7.8e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 BSD domain Thymidylate_kin PF02223.12 CAM65160.1 - 1.1e-34 119.4 0.0 1.3e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.1 CAM65160.1 - 8.5e-07 28.9 0.0 2e-06 27.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CAM65160.1 - 0.0012 19.1 0.1 0.01 16.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CAM65160.1 - 0.0014 18.3 1.6 0.0014 18.3 1.1 2.5 3 1 0 3 3 2 1 Part of AAA domain AAA_22 PF13401.1 CAM65160.1 - 0.0034 17.5 0.0 0.0079 16.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CAM65160.1 - 0.0044 17.0 0.3 0.0079 16.2 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain UPF0079 PF02367.12 CAM65160.1 - 0.013 15.0 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 CAM65160.1 - 0.017 15.3 0.1 0.046 13.9 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 CAM65160.1 - 0.021 13.8 0.0 0.027 13.4 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 CAM65160.1 - 0.027 15.2 0.0 0.045 14.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 CAM65160.1 - 0.039 13.5 3.0 0.082 12.4 0.3 2.3 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.1 CAM65160.1 - 0.15 12.0 0.6 0.33 10.8 0.4 1.8 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 CAM65160.1 - 0.18 11.0 0.1 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein PEPCK_ATP PF01293.15 CAM65160.1 - 0.18 10.2 0.1 0.25 9.7 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase Glyco_transf_11 PF01531.11 CAM65161.1 - 2e-11 43.4 0.6 4.3e-08 32.4 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 11 Glutaredoxin PF00462.19 CAM65162.1 - 5.1e-17 61.6 0.2 1.2e-16 60.4 0.0 1.7 2 0 0 2 2 2 1 Glutaredoxin Mito_fiss_reg PF05308.6 CAM65164.1 - 0.014 14.8 4.4 0.029 13.7 3.1 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator KIAA1328 PF15369.1 CAM65164.1 - 0.93 9.2 12.8 1.2 8.8 8.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 LSM PF01423.17 CAM65167.1 - 4e-08 32.6 0.0 5.2e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain Voltage_CLC PF00654.15 CAM65169.1 - 1.6e-88 297.0 33.6 3.2e-88 296.1 19.5 2.1 2 0 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.23 CAM65169.1 - 8.6e-07 28.6 0.0 0.0014 18.3 0.0 2.4 2 0 0 2 2 2 2 CBS domain cwf21 PF08312.7 CAM65170.1 - 0.045 13.6 0.4 0.045 13.6 0.3 2.5 2 0 0 2 2 2 0 cwf21 domain E3_binding PF02817.12 CAM65170.1 - 0.066 12.8 0.7 2.3 7.9 0.0 2.4 2 0 0 2 2 2 0 e3 binding domain Ribosomal_60s PF00428.14 CAM65170.1 - 0.78 10.1 7.1 0.18 12.2 1.5 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein LMWPc PF01451.16 CAM65171.1 - 3.9e-09 36.9 0.1 6.8e-09 36.1 0.1 1.5 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase DUF1771 PF08590.5 CAM65172.1 - 1.8e-15 56.7 0.2 1.8e-15 56.7 0.1 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) CUE PF02845.11 CAM65172.1 - 1.8e-11 43.2 0.1 2.8e-05 23.5 0.0 4.2 4 0 0 4 4 4 3 CUE domain Smr PF01713.16 CAM65172.1 - 2.7e-10 40.3 0.8 6.6e-10 39.0 0.6 1.8 1 0 0 1 1 1 1 Smr domain UBA PF00627.26 CAM65172.1 - 7.6e-09 35.1 0.3 1.5e-05 24.7 0.1 3.2 3 0 0 3 3 3 2 UBA/TS-N domain Pro_isomerase PF00160.16 CAM65173.1 - 6.4e-37 127.1 0.0 9e-37 126.6 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SNF2_N PF00176.18 CAM65175.2 - 6.5e-41 140.0 0.0 8.8e-41 139.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CAM65175.2 - 5.3e-13 48.6 0.0 1.4e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAM65175.2 - 0.0063 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 CAM65175.2 - 0.0095 14.7 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 CAM65175.2 - 0.016 15.0 0.0 0.17 11.6 0.0 2.4 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Beta_helix PF13229.1 CAM65176.1 - 1.2e-09 38.1 0.3 1.2e-09 38.1 0.2 1.8 2 0 0 2 2 2 1 Right handed beta helix region NosD PF05048.8 CAM65176.1 - 7.4e-06 25.2 0.0 1.2e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Enkurin PF13864.1 CAM65177.1 - 9.3e-20 70.6 9.5 9.3e-20 70.6 6.6 2.0 2 0 0 2 2 2 1 Calmodulin-binding TBPIP PF07106.8 CAM65177.1 - 4.2 6.8 9.0 0.24 10.9 2.5 1.7 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Thioredoxin PF00085.15 CAM65178.1 - 6.9e-21 73.8 0.1 7.5e-21 73.7 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CAM65178.1 - 1.8e-05 24.9 0.4 9.7e-05 22.5 0.3 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CAM65178.1 - 7.1e-05 22.8 0.2 0.0032 17.5 0.1 2.1 1 1 1 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.16 CAM65178.1 - 0.0046 16.6 0.0 0.0054 16.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family HyaE PF07449.6 CAM65178.1 - 0.026 14.3 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.1 CAM65178.1 - 0.029 14.4 0.4 0.057 13.4 0.3 1.5 1 1 0 1 1 1 0 Thioredoxin-like DPM3 PF08285.6 CAM65178.1 - 0.057 13.2 0.0 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Phosducin PF02114.11 CAM65178.1 - 0.061 12.0 0.0 0.064 11.9 0.0 1.1 1 0 0 1 1 1 0 Phosducin PseudoU_synth_2 PF00849.17 CAM65179.1 - 1.5e-21 76.9 0.0 1.1e-20 74.0 0.0 2.1 2 0 0 2 2 2 1 RNA pseudouridylate synthase Cmc1 PF08583.5 CAM65180.1 - 5.6e-06 26.0 2.5 1.1e-05 25.0 1.7 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF4125 PF13526.1 CAM65180.1 - 0.41 10.1 4.0 0.23 10.9 1.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4125) 4F5 PF04419.9 CAM65181.1 - 1.7e-11 44.6 12.1 1.7e-11 44.6 8.4 2.1 2 0 0 2 2 2 1 4F5 protein family DHHA2 PF02833.9 CAM65182.1 - 5.7e-22 78.2 0.1 1.4e-21 76.9 0.0 1.7 2 0 0 2 2 2 1 DHHA2 domain DHH PF01368.15 CAM65182.1 - 1.3e-11 44.3 0.0 1.6e-10 40.8 0.0 2.2 1 1 0 1 1 1 1 DHH family WD40 PF00400.27 CAM65184.1 - 1.7e-10 40.3 12.8 3.6e-06 26.6 0.1 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat PQQ_3 PF13570.1 CAM65184.1 - 0.022 15.0 1.2 9.3 6.6 0.0 4.0 4 0 0 4 4 4 0 PQQ-like domain MPC PF03650.8 CAM65186.1 - 4.3e-14 52.4 0.4 4.8e-14 52.3 0.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) TFIIA PF03153.8 CAM65188.1 - 1.6 8.5 7.7 15 5.3 6.5 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Activator-TraM PF11657.3 CAM65188.1 - 9.4 5.7 7.7 2.3 7.7 2.2 2.1 1 1 1 2 2 2 0 Transcriptional activator TraM DUF788 PF05620.6 CAM65190.1 - 3.9e-37 127.7 0.0 4.7e-37 127.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) Dymeclin PF09742.4 CAM65191.1 - 3.1e-66 223.8 0.0 5e-66 223.2 0.0 1.3 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.2 CAM65191.1 - 0.011 13.4 0.2 1.6 6.3 0.0 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein DUF1664 PF07889.7 CAM65192.2 - 0.0052 16.5 0.6 0.017 14.9 0.4 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Ribosomal_S7e PF01251.13 CAM65194.1 - 2.4e-70 235.9 4.7 2.7e-70 235.7 3.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Ribosomal_S7e PF01251.13 CAM65195.1 - 2.4e-70 235.9 4.7 2.7e-70 235.7 3.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e zf-UBP PF02148.14 CAM65196.1 - 2.7e-10 40.2 9.9 2.7e-10 40.2 6.9 2.5 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 CAM65196.1 - 7.2e-08 32.1 8.9 7.2e-08 32.1 6.2 2.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 CAM65196.1 - 4.2e-05 23.1 16.6 0.0002 20.9 2.2 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CAM65196.1 - 0.00024 21.1 2.8 0.00024 21.1 2.0 2.5 3 0 0 3 3 3 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CAM65196.1 - 0.0027 17.3 7.1 0.0027 17.3 4.9 2.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CAM65196.1 - 0.0029 17.5 8.5 0.0029 17.5 5.9 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CAM65196.1 - 0.013 15.1 8.3 0.013 15.1 5.8 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RecR PF02132.10 CAM65196.1 - 0.036 13.4 3.2 0.96 8.9 0.4 3.0 2 0 0 2 2 2 0 RecR protein DUF2852 PF11014.3 CAM65196.1 - 0.21 11.5 5.6 2.2 8.2 0.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) zf-C3HC4_4 PF15227.1 CAM65196.1 - 6 6.8 21.0 7 6.6 7.5 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF791 PF05631.9 CAM65197.1 - 2.1e-10 39.8 4.8 4.5e-07 28.8 0.2 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF791) Isochorismatase PF00857.15 CAM65198.1 - 1.3e-25 90.3 0.0 1.6e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family AAA_18 PF13238.1 CAM65199.1 - 6.1e-06 26.5 0.0 1.6e-05 25.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CAM65199.1 - 5e-05 24.1 0.0 0.00011 23.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CAM65199.1 - 0.00016 21.7 0.0 0.00047 20.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain mRNA_cap_enzyme PF01331.14 CAM65199.1 - 0.0093 15.6 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain Thymidylate_kin PF02223.12 CAM65199.1 - 0.024 14.0 0.1 0.37 10.1 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase AAA PF00004.24 CAM65199.1 - 0.04 14.1 0.0 0.077 13.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.5 CAM65199.1 - 0.069 12.3 0.0 0.15 11.2 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.1 CAM65199.1 - 0.077 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 CAM65199.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 CAM65199.1 - 0.39 10.3 0.0 0.68 9.6 0.0 1.3 1 0 0 1 1 1 0 NTPase AMP-binding PF00501.23 CAM65200.1 - 1e-84 284.3 0.1 1.5e-84 283.8 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Beta_elim_lyase PF01212.16 CAM65201.1 - 4.9e-42 144.0 0.0 7.5e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 CAM65201.1 - 6.6e-10 38.2 0.1 9.1e-10 37.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 CAM65201.1 - 7.7e-10 38.2 0.0 8.9e-10 38.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Pyridoxal_deC PF00282.14 CAM65201.1 - 0.0027 16.2 0.1 0.0047 15.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain AMP-binding PF00501.23 CAM65202.1 - 7.8e-90 301.2 0.0 1.1e-89 300.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.23 CAM65203.1 - 2e-72 243.8 0.1 3.3e-72 243.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.23 CAM65205.1 - 5.1e-88 295.2 0.2 7.8e-88 294.6 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme PGDYG PF14083.1 CAM65205.1 - 0.032 14.5 0.0 0.091 13.1 0.0 1.7 1 0 0 1 1 1 0 PGDYG protein DUF4476 PF14771.1 CAM65205.1 - 0.069 13.1 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) Campylo_MOMP PF05538.6 CAM65205.1 - 0.081 11.2 0.0 0.13 10.6 0.0 1.2 1 0 0 1 1 1 0 Campylobacter major outer membrane protein AMP-binding PF00501.23 CAM65206.2 - 1.6e-40 138.8 2.2 2.7e-22 78.7 0.1 3.6 3 1 0 3 3 3 3 AMP-binding enzyme PRP3 PF08572.5 CAM65209.1 - 2.5e-27 95.7 0.1 4.4e-27 94.9 0.1 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 CAM65209.1 - 8.5e-17 61.0 0.0 1.6e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) hGDE_N PF14699.1 CAM65209.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain from the human glycogen debranching enzyme Mtc PF03820.12 CAM65210.1 - 3.9e-117 390.2 0.0 4.4e-117 390.1 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier RNA_ligase PF09414.5 CAM65212.1 - 7.5e-53 179.0 0.0 1.3e-52 178.3 0.0 1.4 1 0 0 1 1 1 1 RNA ligase RabGAP-TBC PF00566.13 CAM65213.2 - 5e-29 101.2 0.0 2.9e-13 49.7 0.2 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Asp_protease PF09668.5 CAM65214.1 - 8.5e-58 193.3 0.7 1.1e-57 192.9 0.5 1.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CAM65214.1 - 1.2e-09 37.7 0.0 2.7e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CAM65214.1 - 6.9e-09 36.0 0.0 1.8e-08 34.7 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease UBA_4 PF14555.1 CAM65214.1 - 8.8e-06 25.1 0.1 2e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain RVP_2 PF08284.6 CAM65214.1 - 4e-05 23.5 0.0 6.1e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 CAM65214.1 - 0.00022 21.1 0.0 0.0004 20.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease EF-hand_8 PF13833.1 CAM65215.2 - 0.0024 17.4 0.0 0.0053 16.3 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CAM65215.2 - 0.052 12.8 0.0 0.17 11.2 0.0 1.8 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.1 CAM65215.2 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair HSP70 PF00012.15 CAM65217.1 - 3.5e-27 94.5 1.1 2.8e-17 61.8 0.2 4.0 3 1 1 4 4 4 3 Hsp70 protein MreB_Mbl PF06723.8 CAM65217.1 - 0.0019 16.8 1.0 0.0033 16.0 0.7 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Peptidase_M16 PF00675.15 CAM65218.1 - 4e-42 143.4 0.0 1.7e-41 141.4 0.0 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CAM65218.1 - 1.3e-17 64.0 0.0 5.6e-16 58.7 0.0 3.0 3 1 0 3 3 3 1 Peptidase M16 inactive domain ORC2 PF04084.9 CAM65219.2 - 0.097 11.4 0.0 1.4 7.7 0.0 2.2 2 1 0 2 2 2 0 Origin recognition complex subunit 2 PLAC8 PF04749.12 CAM65222.1 - 2.7e-13 50.4 4.4 4.4e-13 49.6 3.1 1.4 1 1 0 1 1 1 1 PLAC8 family DUF4266 PF14086.1 CAM65222.1 - 8.6 6.9 7.9 89 3.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4266) PLAC8 PF04749.12 CAM65223.1 - 6.7e-09 36.2 7.0 6.1e-05 23.5 1.4 2.4 2 0 0 2 2 2 2 PLAC8 family ThiF PF00899.16 CAM65224.1 - 2.8e-35 121.0 0.1 1.4e-34 118.8 0.0 2.0 1 1 0 1 1 1 1 ThiF family UBACT PF02134.16 CAM65224.1 - 1.2e-15 56.7 0.0 3e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CAM65224.1 - 6.6e-07 28.6 0.7 1.2e-06 27.7 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site ApbA PF02558.11 CAM65224.1 - 0.082 12.3 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Saccharop_dh PF03435.13 CAM65224.1 - 0.1 11.5 0.1 0.34 9.8 0.1 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase CC2D2AN-C2 PF15625.1 CAM65226.1 - 1.1e-35 122.6 0.0 2.4e-35 121.5 0.0 1.6 1 0 0 1 1 1 1 CC2D2A N-terminal C2 domain DUF4478 PF14793.1 CAM65226.1 - 0.068 12.7 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4478) C2 PF00168.25 CAM65226.1 - 0.19 11.5 0.0 0.54 10.1 0.0 1.8 1 0 0 1 1 1 0 C2 domain DUF4336 PF14234.1 CAM65227.1 - 0.11 11.6 0.1 0.37 9.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4336) DUF4407 PF14362.1 CAM65227.1 - 0.8 8.6 11.4 1.2 8.0 7.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pkinase PF00069.20 CAM65228.2 - 2.2e-20 72.9 0.0 1.1e-08 34.6 0.0 4.1 4 1 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 CAM65228.2 - 0.066 12.2 0.0 0.71 8.8 0.0 2.4 3 0 0 3 3 3 0 Protein tyrosine kinase DEAD PF00270.24 CAM65230.1 - 1.2e-39 135.5 0.0 4.9e-39 133.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM65230.1 - 4e-27 93.8 0.3 3.6e-26 90.8 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.1 CAM65230.1 - 3.6e-05 22.9 0.2 0.00012 21.2 0.0 1.8 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.1 CAM65230.1 - 0.15 12.2 2.4 0.25 11.4 0.4 2.4 2 2 0 2 2 2 0 AAA domain DEAD PF00270.24 CAM65231.1 - 1.2e-39 135.5 0.0 4.9e-39 133.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM65231.1 - 4e-27 93.8 0.3 3.6e-26 90.8 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.1 CAM65231.1 - 3.6e-05 22.9 0.2 0.00012 21.2 0.0 1.8 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.1 CAM65231.1 - 0.15 12.2 2.4 0.25 11.4 0.4 2.4 2 2 0 2 2 2 0 AAA domain DUF3128 PF11326.3 CAM65232.1 - 0.0083 16.2 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) zf-C2H2_4 PF13894.1 CAM65233.1 - 0.08 13.3 3.2 0.25 11.7 2.2 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-RING_3 PF14369.1 CAM65233.1 - 0.1 12.6 0.4 0.31 11.0 0.3 1.8 1 0 0 1 1 1 0 zinc-finger zf-C2H2 PF00096.21 CAM65233.1 - 0.37 11.2 1.8 1.1 9.7 1.3 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type Nudix_N_2 PF14803.1 CAM65233.1 - 0.38 10.4 5.2 0.06 13.0 0.6 1.9 2 0 0 2 2 2 0 Nudix N-terminal BK_channel_a PF03493.13 CAM65234.1 - 5.7e-21 74.3 0.0 1.1e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.11 CAM65234.1 - 1.9e-11 43.4 5.4 1.9e-11 43.4 3.8 2.2 3 0 0 3 3 3 1 Ion channel SR-25 PF10500.4 CAM65234.1 - 0.024 14.0 2.6 0.042 13.3 1.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF962 PF06127.6 CAM65234.1 - 0.32 10.9 3.0 0.93 9.4 2.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF962) Ion_trans_2 PF07885.11 CAM65235.1 - 4.1e-11 42.4 5.5 1.4e-10 40.7 3.8 1.9 1 0 0 1 1 1 1 Ion channel BK_channel_a PF03493.13 CAM65235.1 - 3.6e-07 30.0 0.0 5.9e-05 22.9 0.0 2.5 2 0 0 2 2 2 2 Calcium-activated BK potassium channel alpha subunit Peptidase_M24 PF00557.19 CAM65237.2 - 2.9e-40 138.0 1.6 4e-40 137.6 0.1 2.0 3 0 0 3 3 3 1 Metallopeptidase family M24 Creatinase_N PF01321.13 CAM65237.2 - 6.3e-20 72.0 0.2 2.8e-16 60.2 0.0 2.7 2 1 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Cyt-b5 PF00173.23 CAM65238.1 - 1.7e-46 155.9 0.4 1.5e-22 79.1 0.0 2.1 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DUF3931 PF13082.1 CAM65238.1 - 0.11 12.4 0.0 5.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3931) SelR PF01641.13 CAM65242.1 - 0.085 12.5 0.3 1.4 8.6 0.0 2.4 2 1 0 2 2 2 0 SelR domain SRP14 PF02290.10 CAM65243.1 - 0.11 12.4 0.6 3.1 7.7 0.0 2.7 3 0 0 3 3 3 0 Signal recognition particle 14kD protein Stm1_N PF09598.5 CAM65243.1 - 7.9 7.2 10.1 0.15 12.7 1.4 2.3 2 0 0 2 2 2 0 Stm1 zf-CCCH PF00642.19 CAM65244.1 - 0.052 13.2 14.6 0.97 9.1 1.6 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Xpo1 PF08389.7 CAM65245.1 - 1.9e-24 86.2 0.5 4e-23 81.9 0.1 3.0 2 0 0 2 2 2 1 Exportin 1-like protein PI3_PI4_kinase PF00454.22 CAM65246.1 - 5.5e-38 130.7 0.0 1.1e-37 129.7 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 CAM65246.1 - 1.6e-05 24.1 0.0 4e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 FATC domain zf-met PF12874.2 CAM65247.1 - 0.00021 21.3 0.2 0.00048 20.2 0.2 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CAM65247.1 - 0.0033 17.5 0.1 0.0077 16.3 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Troponin PF00992.15 CAM65247.1 - 0.11 12.5 5.1 0.17 11.9 3.5 1.2 1 0 0 1 1 1 0 Troponin PNPase_C PF12111.3 CAM65247.1 - 4.2 6.6 8.1 7.2 5.9 5.6 1.4 1 0 0 1 1 1 0 Polyribonucleotide phosphorylase C terminal zf-C3HC4_3 PF13920.1 CAM65248.1 - 2.4e-07 30.3 7.1 4.1e-07 29.5 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAM65248.1 - 0.059 13.1 8.9 0.11 12.1 6.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 CAM65248.1 - 0.5 10.2 11.2 0.9 9.4 7.7 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.1 CAM65248.1 - 6.5 6.7 9.1 20 5.1 6.3 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Vps51 PF08700.6 CAM65249.1 - 6.1e-10 38.8 0.0 2.5e-09 36.8 0.0 2.0 2 0 0 2 2 2 1 Vps51/Vps67 Galactosyl_T PF01762.16 CAM65250.1 - 0.031 13.8 0.3 0.11 12.0 0.0 2.1 2 0 0 2 2 2 0 Galactosyltransferase Galactosyl_T PF01762.16 CAM65251.1 - 0.1 12.2 0.0 0.1 12.2 0.0 2.6 3 1 0 3 3 3 0 Galactosyltransferase Galactosyl_T PF01762.16 CAM65252.1 - 0.004 16.7 0.6 0.024 14.2 0.0 2.6 3 1 0 3 3 3 1 Galactosyltransferase GlcNAc PF11397.3 CAM65253.1 - 4.3e-06 26.0 0.1 0.006 15.7 0.0 2.9 2 1 0 2 2 2 2 Glycosyltransferase (GlcNAc) Ras PF00071.17 CAM65254.1 - 1.2e-53 180.8 0.1 1.4e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAM65254.1 - 4e-22 78.9 0.0 6.1e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAM65254.1 - 2.1e-15 56.3 0.0 2.6e-15 56.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CAM65254.1 - 1.4e-06 27.6 0.2 1.8e-06 27.2 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CAM65254.1 - 4.6e-06 26.1 0.1 1.3e-05 24.7 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CAM65254.1 - 0.00071 18.8 0.0 0.0012 18.1 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CAM65254.1 - 0.0072 16.2 0.0 0.018 14.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CAM65254.1 - 0.039 13.2 0.1 2.3 7.4 0.1 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B PduV-EutP PF10662.4 CAM65254.1 - 0.051 13.0 0.2 8.5 5.8 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation UPF0158 PF03682.8 CAM65255.1 - 0.082 12.5 0.1 0.086 12.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) DUF2464 PF10240.4 CAM65256.1 - 0.005 16.2 0.3 0.0064 15.8 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2464) PAP1 PF08601.5 CAM65256.1 - 4.1 6.9 6.0 4.9 6.7 4.2 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 HemX PF04375.9 CAM65256.1 - 5.2 5.5 8.3 6.6 5.2 5.7 1.1 1 0 0 1 1 1 0 HemX DUF3544 PF12064.3 CAM65256.1 - 6.1 6.5 11.1 8.9 6.0 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3544) Pkinase PF00069.20 CAM65257.1 - 2.3e-48 164.6 0.0 7.7e-48 162.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM65257.1 - 3.3e-30 105.0 0.0 4.4e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM65257.1 - 3e-09 36.2 0.0 4.6e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like ABC2_membrane_3 PF12698.2 CAM65258.1 - 1.9e-54 185.0 40.0 1.2e-32 113.3 9.7 2.8 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.22 CAM65258.1 - 4.7e-39 133.8 0.0 8.1e-23 81.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CAM65258.1 - 3e-14 53.6 0.4 1.1e-05 25.5 0.0 4.0 3 1 0 4 4 4 2 AAA domain SMC_N PF02463.14 CAM65258.1 - 0.0025 17.0 0.0 3.3 6.8 0.0 3.0 2 2 0 4 4 4 1 RecF/RecN/SMC N terminal domain DUF1049 PF06305.6 CAM65258.1 - 0.034 13.6 2.5 0.22 11.0 1.7 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Peptidase_M50 PF02163.17 CAM65258.1 - 0.051 12.5 0.0 0.21 10.5 0.0 2.1 1 0 0 1 1 1 0 Peptidase family M50 DUF87 PF01935.12 CAM65258.1 - 0.15 11.8 0.0 0.41 10.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF87 ABC2_membrane PF01061.19 CAM65258.1 - 0.58 9.2 54.8 0.21 10.7 17.7 3.8 4 1 0 4 4 4 0 ABC-2 type transporter AAA_15 PF13175.1 CAM65258.1 - 0.91 8.5 0.0 11 4.9 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain AAA_23 PF13476.1 CAM65258.1 - 5.5 7.2 2.1 3.4 7.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain SNAP PF14938.1 CAM65259.1 - 5.9e-15 55.1 15.1 2.1e-11 43.4 4.7 3.2 3 0 0 3 3 3 3 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 CAM65259.1 - 0.88 9.5 13.8 1.3 9.0 1.0 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat RNase_PH PF01138.16 CAM65260.1 - 1.4e-17 64.2 0.0 2.4e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Glyco_transf_10 PF00852.14 CAM65261.1 - 7.7e-18 64.1 0.0 1.6e-12 46.6 0.0 2.9 2 1 0 2 2 2 2 Glycosyltransferase family 10 (fucosyltransferase) SecY PF00344.15 CAM65261.1 - 0.81 8.5 0.1 1.2 7.9 0.1 1.1 1 0 0 1 1 1 0 SecY translocase UAA PF08449.6 CAM65262.1 - 4.5e-18 65.2 16.3 3.1e-12 46.0 3.7 4.0 4 0 0 4 4 4 3 UAA transporter family TPT PF03151.11 CAM65262.1 - 1.6e-10 40.8 2.0 5.7e-10 39.0 0.6 2.6 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 CAM65262.1 - 1.2e-05 25.3 4.2 1.2e-05 25.3 2.9 2.7 4 0 0 4 4 4 1 EamA-like transporter family Pkinase PF00069.20 CAM65264.1 - 8.3e-53 179.1 0.0 1e-52 178.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM65264.1 - 4e-20 71.9 0.0 5.3e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CAM65264.1 - 1.1e-06 28.5 0.2 0.00033 20.4 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 CAM65264.1 - 0.00082 18.7 0.1 0.0013 18.0 0.1 1.2 1 0 0 1 1 1 1 RIO1 family PCI PF01399.22 CAM65265.1 - 7.4e-12 45.5 1.8 7.6e-12 45.4 0.1 1.9 2 0 0 2 2 2 1 PCI domain TPR_19 PF14559.1 CAM65265.1 - 0.0037 17.5 2.3 3.4 8.0 0.1 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CAM65265.1 - 0.16 12.6 0.1 0.16 12.6 0.0 4.4 5 1 1 6 6 6 0 Tetratricopeptide repeat FtsJ PF01728.14 CAM65266.1 - 7.7e-62 208.4 0.0 1e-61 208.0 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase UQ_con PF00179.21 CAM65267.1 - 2.6e-40 137.0 0.0 3.1e-40 136.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CAM65267.1 - 0.00013 21.7 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B ESSS PF10183.4 CAM65270.1 - 0.026 14.8 0.0 0.49 10.8 0.0 2.9 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) SPC25 PF06703.6 CAM65270.1 - 0.21 11.1 0.0 0.49 9.9 0.0 1.5 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) PSI PF01437.20 CAM65270.1 - 4.9 7.3 11.6 0.97 9.6 3.9 2.5 2 1 0 2 2 2 0 Plexin repeat Rhomboid PF01694.17 CAM65271.1 - 3.7e-06 27.0 8.1 0.0011 18.9 0.9 2.8 3 0 0 3 3 3 2 Rhomboid family Glyco_hydro_20b PF02838.10 CAM65273.1 - 0.11 13.0 0.1 0.3 11.6 0.1 1.7 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 Porin_3 PF01459.17 CAM65274.1 - 2.6e-06 26.9 0.0 6.9e-06 25.5 0.0 2.1 1 1 0 1 1 1 1 Eukaryotic porin SLX9 PF15341.1 CAM65276.1 - 0.00018 21.8 9.4 0.0014 19.0 6.5 2.4 1 1 0 1 1 1 1 Ribosome biogenesis protein SLX9 Paramyxo_C PF01692.13 CAM65276.1 - 0.033 13.8 0.1 0.052 13.1 0.1 1.3 1 1 0 1 1 1 0 Paramyxovirus non-structural protein c Aldedh PF00171.17 CAM65276.1 - 0.071 11.4 1.3 0.088 11.1 0.9 1.1 1 0 0 1 1 1 0 Aldehyde dehydrogenase family Gly_kinase PF02595.10 CAM65278.1 - 9.8e-27 93.6 17.7 3.1e-06 26.1 0.1 7.2 6 1 1 7 7 7 7 Glycerate kinase family FGE-sulfatase PF03781.11 CAM65279.1 - 0.052 12.8 0.9 0.085 12.1 0.6 1.5 1 1 0 1 1 1 0 Sulfatase-modifying factor enzyme 1 DUF3592 PF12158.3 CAM65282.1 - 0.27 11.0 0.1 0.27 11.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3592) GtrA PF04138.9 CAM65282.1 - 0.46 10.4 4.9 8.1 6.4 2.4 2.5 2 0 0 2 2 2 0 GtrA-like protein Pkinase PF00069.20 CAM65285.1 - 2e-59 200.8 0.0 5.9e-59 199.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM65285.1 - 3.8e-37 127.7 0.0 8.4e-32 110.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CAM65285.1 - 2.7e-05 23.2 0.0 0.0002 20.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CAM65285.1 - 0.00023 21.0 1.3 0.002 17.9 0.1 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.17 CAM65285.1 - 0.00043 19.6 0.2 0.001 18.4 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Sre PF03125.13 CAM65285.1 - 0.019 13.8 0.6 0.03 13.2 0.4 1.1 1 0 0 1 1 1 0 C. elegans Sre G protein-coupled chemoreceptor Snf7 PF03357.16 CAM65286.2 - 0.022 14.1 4.9 0.04 13.3 3.4 1.3 1 0 0 1 1 1 0 Snf7 DUF2317 PF10079.4 CAM65286.2 - 0.3 9.6 0.3 0.52 8.8 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) TPR_11 PF13414.1 CAM65287.1 - 9.1e-15 54.0 10.5 1.7e-07 30.7 0.6 2.5 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 CAM65287.1 - 5.4e-09 35.2 4.0 1.6e-07 30.6 1.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 CAM65287.1 - 6.4e-08 31.9 9.1 1.6e-06 27.5 1.5 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CAM65287.1 - 4.7e-06 25.9 1.5 1.3e-05 24.5 0.5 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 CAM65287.1 - 0.00037 20.0 4.8 0.063 13.1 0.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CAM65287.1 - 0.0047 17.5 3.3 0.0047 17.5 2.3 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 CAM65287.1 - 0.018 14.8 1.4 0.018 14.8 1.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 CAM65287.1 - 0.046 14.3 0.3 0.046 14.3 0.2 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 CAM65287.1 - 0.1 13.0 3.3 1.3 9.6 1.0 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CAM65287.1 - 0.16 11.8 0.2 0.16 11.8 0.1 2.6 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat ARPC4 PF05856.7 CAM65288.1 - 1.6e-58 196.8 0.0 1.8e-58 196.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) DUF3584 PF12128.3 CAM65289.1 - 0.29 8.4 21.6 0.37 8.0 14.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF940 PF06082.6 CAM65289.1 - 0.33 9.4 4.3 0.45 9.0 3.0 1.2 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) UBN2 PF14223.1 CAM65289.1 - 0.68 9.7 8.0 0.37 10.5 0.4 2.6 2 1 0 3 3 3 0 gag-polypeptide of LTR copia-type LMBR1 PF04791.11 CAM65289.1 - 2.4 6.6 8.2 1.5 7.3 4.3 1.5 1 1 1 2 2 2 0 LMBR1-like membrane protein Syntaxin PF00804.20 CAM65289.1 - 3.5 7.8 15.6 2.8e+02 1.7 10.8 2.4 1 1 0 1 1 1 0 Syntaxin CENP-H PF05837.7 CAM65289.1 - 3.5 7.8 18.1 0.46 10.6 4.6 2.5 2 1 0 2 2 2 0 Centromere protein H (CENP-H) LLC1 PF14945.1 CAM65289.1 - 8.8 6.6 7.9 4.2 7.7 0.3 3.1 2 1 1 3 3 3 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Tup_N PF08581.5 CAM65289.1 - 8.8 6.5 14.1 0.44 10.7 4.7 2.3 2 1 0 2 2 2 0 Tup N-terminal WD40 PF00400.27 CAM65290.1 - 0.00055 19.7 11.6 0.0062 16.3 0.3 5.2 5 1 0 5 5 5 3 WD domain, G-beta repeat Aldedh PF00171.17 CAM65291.1 - 7.9e-05 21.1 0.6 0.014 13.7 0.0 2.4 2 1 0 2 2 2 2 Aldehyde dehydrogenase family LRR_4 PF12799.2 CAM65292.1 - 7.3e-14 51.0 0.0 0.037 13.6 0.0 8.3 9 1 1 10 10 10 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM65292.1 - 1.2e-10 41.0 0.4 0.27 11.0 0.0 6.3 7 1 1 8 8 8 5 Leucine rich repeat LRR_6 PF13516.1 CAM65292.1 - 3.2e-07 29.7 1.5 24 5.3 0.0 9.0 13 0 0 13 13 13 1 Leucine Rich repeat LRR_1 PF00560.28 CAM65292.1 - 0.00013 21.5 12.2 63 4.1 0.0 10.6 13 1 0 13 13 13 0 Leucine Rich Repeat Nop14 PF04147.7 CAM65294.1 - 1.7e-42 145.4 19.7 1.6e-31 109.1 0.7 3.0 1 1 1 2 2 2 2 Nop14-like family Mito_carr PF00153.22 CAM65295.1 - 4.4e-29 100.0 4.4 1.7e-15 56.5 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein TFIIE_alpha PF02002.12 CAM65296.1 - 0.055 12.9 0.1 0.097 12.1 0.1 1.5 1 1 0 1 1 1 0 TFIIE alpha subunit Seryl_tRNA_N PF02403.17 CAM65298.1 - 0.015 15.3 1.7 0.015 15.3 1.2 8.5 4 4 4 8 8 8 0 Seryl-tRNA synthetase N-terminal domain Reo_sigmaC PF04582.7 CAM65298.1 - 0.094 11.8 25.3 0.19 10.8 2.7 4.9 1 1 0 4 4 4 0 Reovirus sigma C capsid protein Ribosomal_S10 PF00338.17 CAM65298.1 - 2.1 8.2 6.1 1.5 8.7 0.1 3.5 3 1 1 4 4 4 0 Ribosomal protein S10p/S20e SpoU_sub_bind PF08032.7 CAM65298.1 - 3.2 7.9 11.5 0.084 13.0 0.3 3.9 4 0 0 4 4 4 0 RNA 2'-O ribose methyltransferase substrate binding AAA_2 PF07724.9 CAM65299.1 - 1.8e-51 174.4 0.0 5.8e-49 166.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 CAM65299.1 - 2e-24 86.3 0.3 7.8e-14 52.0 0.0 3.7 3 1 1 4 4 3 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 CAM65299.1 - 3.7e-22 78.0 0.2 1.5e-21 76.0 0.1 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 CAM65299.1 - 3.7e-18 65.6 0.2 4.2e-11 42.7 0.0 4.1 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CAM65299.1 - 1.6e-12 47.7 3.0 0.00027 20.9 0.0 4.7 3 3 2 5 5 4 3 AAA ATPase domain AAA_22 PF13401.1 CAM65299.1 - 8e-11 42.1 3.2 0.00012 22.2 0.0 4.8 3 2 2 5 5 4 2 AAA domain AAA_17 PF13207.1 CAM65299.1 - 2.9e-07 31.3 0.9 0.0069 17.1 0.0 3.5 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 CAM65299.1 - 9.2e-06 25.9 4.6 0.063 13.5 0.0 3.6 3 1 0 3 3 3 2 AAA domain IstB_IS21 PF01695.12 CAM65299.1 - 1.5e-05 24.5 0.0 0.026 13.9 0.0 2.9 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 CAM65299.1 - 2.9e-05 23.3 0.0 0.88 8.6 0.0 3.7 2 1 0 3 3 3 2 Magnesium chelatase, subunit ChlI DNA_pol3_delta2 PF13177.1 CAM65299.1 - 4.3e-05 23.2 1.1 0.011 15.4 0.0 4.1 3 2 0 3 3 3 1 DNA polymerase III, delta subunit RNA_helicase PF00910.17 CAM65299.1 - 4.4e-05 23.6 0.0 0.7 10.0 0.0 3.1 3 0 0 3 3 2 2 RNA helicase AAA_14 PF13173.1 CAM65299.1 - 5.2e-05 23.1 0.9 0.4 10.5 0.0 3.5 4 0 0 4 4 3 2 AAA domain AAA_25 PF13481.1 CAM65299.1 - 0.00018 20.9 0.0 2.4 7.4 0.0 3.7 2 1 0 3 3 3 2 AAA domain Sigma54_activat PF00158.21 CAM65299.1 - 0.00023 20.6 0.0 0.13 11.7 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.6 CAM65299.1 - 0.00032 20.3 0.0 0.57 9.8 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CAM65299.1 - 0.00036 20.2 0.1 0.047 13.3 0.0 3.5 3 0 0 3 3 3 1 NACHT domain RuvB_N PF05496.7 CAM65299.1 - 0.00048 19.2 0.3 0.93 8.4 0.0 3.3 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CAM65299.1 - 0.00081 19.0 0.0 0.095 12.4 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain MobB PF03205.9 CAM65299.1 - 0.001 18.7 0.0 0.31 10.7 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Ribosomal_S7 PF00177.16 CAM65299.1 - 0.0035 16.9 0.2 0.014 15.0 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e AAA_28 PF13521.1 CAM65299.1 - 0.0037 17.2 0.0 1.4 8.8 0.0 3.2 3 0 0 3 3 2 1 AAA domain SRP54 PF00448.17 CAM65299.1 - 0.0063 15.9 0.0 1.1 8.7 0.0 3.2 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain DUF815 PF05673.8 CAM65299.1 - 0.0064 15.4 0.1 0.23 10.3 0.0 3.3 5 0 0 5 5 4 1 Protein of unknown function (DUF815) DEAD PF00270.24 CAM65299.1 - 0.0098 15.3 0.1 8.6 5.8 0.0 3.4 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_24 PF13479.1 CAM65299.1 - 0.01 15.4 0.0 1 8.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 CAM65299.1 - 0.012 15.4 4.0 2.9 7.6 0.0 4.0 3 1 1 4 4 4 0 Type III restriction enzyme, res subunit DUF258 PF03193.11 CAM65299.1 - 0.013 14.6 0.0 2.3 7.3 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 CAM65299.1 - 0.017 14.8 0.1 3.6 7.2 0.0 3.2 3 0 0 3 3 3 0 NTPase ABC_tran PF00005.22 CAM65299.1 - 0.021 15.1 1.4 8.1 6.7 0.0 3.5 3 1 0 3 3 3 0 ABC transporter AAA_33 PF13671.1 CAM65299.1 - 0.03 14.1 0.0 8.1 6.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CAM65299.1 - 0.03 13.8 0.0 5.2 6.6 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Torsin PF06309.6 CAM65299.1 - 0.042 13.7 0.0 0.14 12.0 0.0 1.8 2 0 0 2 2 1 0 Torsin Miro PF08477.8 CAM65299.1 - 0.044 14.2 0.1 0.41 11.1 0.0 2.6 3 0 0 3 3 1 0 Miro-like protein AAA_10 PF12846.2 CAM65299.1 - 0.045 13.1 2.2 13 5.0 0.0 4.0 3 2 1 4 4 4 0 AAA-like domain UPF0079 PF02367.12 CAM65299.1 - 0.061 12.9 0.0 13 5.4 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MMR_HSR1 PF01926.18 CAM65299.1 - 0.081 12.8 0.1 2.3 8.2 0.0 2.9 3 0 0 3 3 2 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 CAM65299.1 - 0.087 12.3 0.0 3 7.3 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein V_ATPase_I PF01496.14 CAM65299.1 - 0.16 9.7 8.4 0.23 9.2 5.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family 4HB_MCP_1 PF12729.2 CAM65299.1 - 0.17 11.2 7.8 0.34 10.2 5.4 1.5 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction DUF310 PF03750.8 CAM65299.1 - 0.97 9.6 5.3 8.4 6.6 1.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF310) IncA PF04156.9 CAM65299.1 - 3.4 7.2 10.7 8.5 5.9 7.4 1.6 1 0 0 1 1 1 0 IncA protein Peptidase_M3 PF01432.15 CAM65302.2 - 1.1e-136 456.5 0.0 1.8e-136 455.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 CAM65302.2 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like DUF2370 PF10176.4 CAM65303.1 - 0.13 11.5 4.5 0.11 11.8 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) Galactosyl_T PF01762.16 CAM65304.2 - 0.0099 15.4 0.8 0.036 13.6 0.0 2.4 3 1 0 3 3 3 1 Galactosyltransferase Galactosyl_T PF01762.16 CAM65306.1 - 0.0073 15.9 0.0 0.02 14.5 0.0 1.7 1 0 0 1 1 1 1 Galactosyltransferase GlcNAc PF11397.3 CAM65307.1 - 6.4e-121 403.6 0.0 8.9e-121 403.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) Galactosyl_T PF01762.16 CAM65308.1 - 0.012 15.2 4.0 0.013 15.0 0.0 2.9 3 1 0 3 3 3 0 Galactosyltransferase SpoVAD PF07451.6 CAM65309.1 - 0.047 12.1 0.1 0.075 11.4 0.0 1.2 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) MS_channel PF00924.13 CAM65310.1 - 2.6 7.3 5.4 0.51 9.6 0.3 2.4 3 0 0 3 3 3 0 Mechanosensitive ion channel Arf PF00025.16 CAM65312.1 - 3.2e-54 182.7 0.0 3.7e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 CAM65312.1 - 1.5e-08 33.7 0.9 4.2e-06 25.6 0.0 2.5 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 CAM65312.1 - 2.2e-08 33.5 0.0 2.9e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 CAM65312.1 - 6.1e-08 33.1 0.0 7.8e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 CAM65312.1 - 2.3e-07 30.3 0.0 2.9e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 CAM65312.1 - 3.6e-06 26.9 0.0 6.2e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CAM65312.1 - 1.8e-05 24.0 0.0 2.2e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CAM65312.1 - 3.2e-05 23.4 0.1 0.0076 15.7 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CAM65312.1 - 0.043 13.0 0.0 0.26 10.5 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B cobW PF02492.14 CAM65312.1 - 0.043 13.2 0.1 4 6.8 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.17 CAM65312.1 - 0.048 13.1 0.2 0.1 11.9 0.1 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.4 CAM65312.1 - 0.094 12.2 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Bacillus_HBL PF05791.6 CAM65313.1 - 0.0022 17.4 2.8 0.0022 17.4 2.0 5.4 3 1 1 5 5 5 2 Bacillus haemolytic enterotoxin (HBL) DUF1878 PF08963.5 CAM65314.1 - 0.2 11.8 7.3 0.18 11.9 0.6 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1878) MVP_shoulder PF11978.3 CAM65315.1 - 3.2e-50 168.9 0.1 6.5e-50 167.9 0.1 1.5 1 0 0 1 1 1 1 Shoulder domain Vault PF01505.13 CAM65315.1 - 4.9e-46 154.5 8.4 6.3e-11 42.1 0.1 6.2 6 0 0 6 6 6 5 Major Vault Protein repeat DUF3601 PF12208.3 CAM65315.1 - 0.00071 19.4 0.0 3.8 7.5 0.0 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF3601) LRR_6 PF13516.1 CAM65316.1 - 1.2e-30 102.0 19.7 0.00074 19.3 0.2 10.4 9 2 2 11 11 11 8 Leucine Rich repeat LRR_4 PF12799.2 CAM65316.1 - 2.8e-13 49.1 5.2 9.7e-06 25.0 0.0 5.4 5 1 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CAM65316.1 - 5.1e-11 41.0 5.3 0.12 12.5 0.0 7.4 7 0 0 7 7 7 3 Leucine Rich Repeat LRR_7 PF13504.1 CAM65316.1 - 1.4e-05 24.4 11.9 5.8 7.5 0.0 7.8 8 0 0 8 8 8 2 Leucine rich repeat LRR_8 PF13855.1 CAM65316.1 - 0.00025 20.7 13.1 0.055 13.2 0.2 4.9 4 3 1 5 5 5 3 Leucine rich repeat LRR_2 PF07723.8 CAM65316.1 - 0.15 12.6 0.5 54 4.5 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich Repeat 2H-phosphodiest PF08975.5 CAM65317.1 - 0.028 14.1 0.4 0.09 12.5 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1868) Lebercilin PF15619.1 CAM65317.1 - 0.055 12.8 37.4 0.082 12.3 12.2 2.5 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Fez1 PF06818.10 CAM65317.1 - 1.1 9.2 44.4 3.3 7.6 8.1 2.2 2 0 0 2 2 2 0 Fez1 CENP-Q PF13094.1 CAM65317.1 - 3.7 7.5 45.5 2.4 8.1 7.3 3.3 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Fip1 PF05182.8 CAM65320.1 - 2.6e-21 74.6 0.3 4e-21 73.9 0.2 1.3 1 0 0 1 1 1 1 Fip1 motif zf-CCCH PF00642.19 CAM65320.1 - 5.8e-11 41.7 2.9 1.2e-10 40.7 2.0 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MMR_HSR1 PF01926.18 CAM65321.2 - 6.5e-16 58.3 0.1 5e-14 52.2 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CAM65321.2 - 8.6e-06 25.1 0.0 3.2e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.11 CAM65321.2 - 0.00022 20.3 0.0 0.00045 19.3 0.0 1.5 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 CAM65321.2 - 0.019 14.1 0.0 0.038 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Miro PF08477.8 CAM65321.2 - 0.029 14.8 0.0 0.14 12.6 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein GTP_EFTU PF00009.22 CAM65321.2 - 0.12 11.8 0.1 7 6.0 0.0 3.0 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CAM65321.2 - 0.16 11.7 0.9 0.38 10.5 0.0 2.1 2 0 0 2 2 2 0 Dynamin family Dynein_light PF01221.13 CAM65323.1 - 1.6e-31 108.0 0.5 1.8e-31 107.9 0.3 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Vasohibin PF14822.1 CAM65323.1 - 0.02 13.9 0.2 0.023 13.7 0.1 1.3 1 1 0 1 1 1 0 Vasohibin Rrp15p PF07890.7 CAM65324.1 - 1.6e-06 28.2 15.3 4.4e-06 26.7 10.6 1.7 1 1 0 1 1 1 1 Rrp15p NUDIX PF00293.23 CAM65325.1 - 1.9e-14 53.4 0.0 2.7e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Metallophos PF00149.23 CAM65326.1 - 5.1e-30 104.3 0.1 8e-30 103.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Plus-3 PF03126.13 CAM65326.1 - 0.00018 21.5 0.0 0.00037 20.5 0.0 1.5 1 0 0 1 1 1 1 Plus-3 domain Metallophos_2 PF12850.2 CAM65326.1 - 0.00066 19.5 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Methyltransf_4 PF02390.12 CAM65328.1 - 0.0079 15.2 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Pkinase PF00069.20 CAM65329.1 - 3.4e-54 183.7 0.1 7.5e-54 182.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM65329.1 - 2.7e-29 102.0 0.1 2.2e-27 95.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CAM65329.1 - 0.00026 20.8 0.1 0.0014 18.3 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CAM65329.1 - 0.0019 17.3 0.0 0.0033 16.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CAM65329.1 - 0.0085 15.4 1.1 0.018 14.4 0.7 1.5 1 1 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.4 CAM65329.1 - 0.046 13.0 0.1 0.073 12.4 0.1 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DEAD PF00270.24 CAM65330.2 - 2.1e-39 134.7 0.0 9.6e-38 129.3 0.0 2.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase GUCT PF08152.7 CAM65330.2 - 4.9e-27 93.7 0.0 1e-26 92.7 0.0 1.5 1 0 0 1 1 1 1 GUCT (NUC152) domain Helicase_C PF00271.26 CAM65330.2 - 5.6e-24 83.7 0.0 1.7e-23 82.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAM65330.2 - 0.0023 17.7 0.1 0.046 13.5 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CRA PF06589.6 CAM65330.2 - 0.077 12.3 0.0 0.23 10.7 0.0 1.8 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Ank PF00023.25 CAM65332.1 - 2e-06 27.2 0.0 5.6e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 CAM65332.1 - 1.3e-05 25.4 0.1 5.1e-05 23.5 0.0 2.1 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CAM65332.1 - 0.00021 21.2 0.1 0.00089 19.2 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 CAM65332.1 - 0.0046 17.1 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 CAM65332.1 - 0.0049 17.3 0.0 0.013 16.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) MCPVI PF02993.9 CAM65333.1 - 0.026 14.6 5.3 0.13 12.4 0.5 2.3 2 0 0 2 2 2 0 Minor capsid protein VI PTPLA PF04387.9 CAM65334.1 - 2.9e-57 192.6 6.0 3.7e-57 192.3 4.1 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA P16-Arc PF04699.9 CAM65335.1 - 5.1e-06 26.5 0.0 5.5e-06 26.4 0.0 1.3 1 1 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Mito_carr PF00153.22 CAM65336.1 - 2.5e-43 145.6 10.2 6.6e-14 51.3 0.0 5.0 5 1 0 5 5 5 3 Mitochondrial carrier protein Glutaredoxin PF00462.19 CAM65338.1 - 1.4e-15 56.9 0.0 2e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Pil1 PF13805.1 CAM65338.1 - 0.13 11.4 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Eisosome component PIL1 MCM PF00493.18 CAM65339.1 - 1.2e-89 300.3 0.0 6.7e-80 268.3 0.0 2.1 2 0 0 2 2 2 2 MCM2/3/5 family AAA_5 PF07728.9 CAM65339.1 - 1.4e-08 34.5 0.0 3.2e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CAM65339.1 - 0.00022 20.4 0.2 0.11 11.6 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CAM65339.1 - 0.00056 19.5 0.0 0.0015 18.1 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CAM65339.1 - 0.011 15.2 0.1 0.043 13.2 0.1 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.1 CAM65339.1 - 0.018 15.0 1.6 0.038 13.9 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 CAM65339.1 - 0.02 15.0 0.0 0.068 13.3 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MTH865 PF07747.6 CAM65339.1 - 0.13 11.9 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 MTH865-like family AAA_2 PF07724.9 CAM65339.1 - 0.16 11.8 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Ribosomal_S11 PF00411.14 CAM65340.1 - 0.0061 16.7 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S11 DSPc PF00782.15 CAM65341.2 - 1.4e-33 115.2 0.1 2.2e-33 114.6 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CAM65341.2 - 4e-05 23.0 0.0 6.7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 CAM65341.2 - 0.0033 16.3 0.1 0.005 15.7 0.0 1.2 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase2 PF03162.8 CAM65341.2 - 0.0065 15.8 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Fe_hyd_lg_C PF02906.9 CAM65342.1 - 1.1e-64 218.5 0.1 1.7e-63 214.5 0.0 2.1 2 0 0 2 2 2 2 Iron only hydrogenase large subunit, C-terminal domain Pyr_redox_2 PF07992.9 CAM65344.1 - 1.9e-33 116.0 0.3 9.9e-33 113.7 0.2 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 CAM65344.1 - 2.8e-28 98.1 0.2 4.9e-28 97.3 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 CAM65344.1 - 5e-19 68.4 0.1 2.9e-16 59.6 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CAM65344.1 - 2.3e-07 31.0 0.5 0.0016 18.5 0.1 3.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CAM65344.1 - 0.00014 20.8 2.1 0.021 13.6 0.8 2.4 3 0 0 3 3 3 2 FAD binding domain HI0933_like PF03486.9 CAM65344.1 - 0.00025 19.6 1.4 0.42 9.0 0.5 2.5 2 0 0 2 2 2 2 HI0933-like protein PALP PF00291.20 CAM65344.1 - 0.011 15.0 0.1 0.021 14.0 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme GIDA PF01134.17 CAM65344.1 - 0.061 12.1 0.4 0.1 11.4 0.3 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 CAM65344.1 - 0.068 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding DEAD PF00270.24 CAM65345.1 - 2.2e-38 131.4 0.0 3.6e-38 130.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM65345.1 - 8.4e-22 76.8 0.0 1.8e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAM65345.1 - 0.00012 22.0 0.0 0.0028 17.4 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Pkinase PF00069.20 CAM65348.1 - 1.9e-67 227.1 0.0 2.5e-67 226.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM65348.1 - 2.9e-49 167.4 0.0 4.3e-49 166.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase MORN PF02493.15 CAM65348.1 - 3.7e-42 139.5 46.3 3.9e-10 38.8 2.6 8.7 8 0 0 8 8 8 8 MORN repeat Kinase-like PF14531.1 CAM65348.1 - 0.00097 18.1 0.0 0.0018 17.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CAM65348.1 - 0.058 12.7 0.0 0.4 10.0 0.0 1.9 2 0 0 2 2 2 0 RIO1 family SMC_N PF02463.14 CAM65349.2 - 2.1e-59 200.4 0.0 3.9e-59 199.5 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CAM65349.2 - 1.5e-15 57.9 0.1 2.2e-07 31.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 CAM65349.2 - 2.3e-13 50.9 12.4 2.3e-13 50.9 8.6 6.2 2 2 1 3 3 3 1 AAA domain SMC_hinge PF06470.8 CAM65349.2 - 4.3e-11 42.8 0.2 1.9e-10 40.7 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_29 PF13555.1 CAM65349.2 - 4.5e-05 22.9 0.0 0.00011 21.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 CAM65349.2 - 0.00028 20.0 0.0 0.00098 18.2 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 CAM65349.2 - 0.33 11.2 21.9 1.8 8.8 0.0 6.0 3 2 0 3 3 3 0 ABC transporter Myosin_tail_1 PF01576.14 CAM65349.2 - 8 4.0 114.4 0.0085 13.8 34.2 3.1 3 0 0 3 3 3 0 Myosin tail TPR_2 PF07719.12 CAM65350.1 - 3.4e-22 76.5 19.5 0.00047 19.8 0.1 10.0 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_11 PF13414.1 CAM65350.1 - 4.8e-19 67.7 25.5 1.2e-07 31.2 0.1 7.7 4 1 4 8 8 8 5 TPR repeat TPR_1 PF00515.23 CAM65350.1 - 7.5e-17 60.1 7.7 0.022 14.3 0.1 8.7 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 CAM65350.1 - 2.6e-13 50.2 47.6 0.0007 20.1 0.4 9.4 6 1 6 12 12 12 7 Tetratricopeptide repeat TPR_14 PF13428.1 CAM65350.1 - 7.3e-13 47.9 43.7 0.0043 17.5 0.2 10.9 8 2 4 12 12 10 5 Tetratricopeptide repeat TPR_12 PF13424.1 CAM65350.1 - 2.9e-11 43.1 31.3 0.018 14.9 1.0 8.9 6 1 3 10 10 10 6 Tetratricopeptide repeat Apc3 PF12895.2 CAM65350.1 - 4e-11 42.8 22.6 0.0021 18.1 0.1 6.5 5 2 2 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 CAM65350.1 - 9.4e-11 41.9 32.7 2.6e-05 24.4 0.4 8.5 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.1 CAM65350.1 - 7.8e-10 38.1 7.8 0.0019 18.2 0.0 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.1 CAM65350.1 - 3.9e-07 29.3 0.0 0.59 10.0 0.0 6.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.1 CAM65350.1 - 1.8e-06 27.2 4.7 0.86 9.5 0.1 6.5 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 CAM65350.1 - 6.3e-05 23.1 20.6 0.74 10.4 0.0 9.0 10 0 0 10 10 8 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CAM65350.1 - 0.00024 20.9 0.9 0.1 12.5 0.1 4.0 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.12 CAM65350.1 - 0.00038 20.7 3.4 0.00038 20.7 2.4 5.3 4 2 2 6 6 6 1 Bacterial transcriptional activator domain TPR_9 PF13371.1 CAM65350.1 - 0.0023 17.7 1.2 0.0023 17.7 0.8 7.1 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.1 CAM65350.1 - 1.8 8.5 18.3 15 5.6 0.0 7.1 9 0 0 9 9 7 0 Tetratricopeptide repeat Tctex-1 PF03645.8 CAM65351.1 - 1.7e-25 88.8 1.2 1.9e-25 88.6 0.8 1.0 1 0 0 1 1 1 1 Tctex-1 family Metallophos PF00149.23 CAM65352.1 - 0.00016 21.1 0.0 0.00052 19.4 0.0 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Skp1 PF01466.14 CAM65354.1 - 0.00062 19.7 0.0 0.00094 19.1 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain NGP1NT PF08153.7 CAM65355.1 - 4.9e-45 152.6 0.7 4.9e-45 152.6 0.5 2.0 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 CAM65355.1 - 9.6e-20 70.6 0.2 4.8e-16 58.7 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CAM65355.1 - 3.1e-05 23.3 0.1 0.00019 20.7 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 CAM65355.1 - 0.00045 19.6 0.0 0.27 10.6 0.0 3.4 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CAM65355.1 - 0.0021 17.9 7.5 0.44 10.3 0.0 4.4 3 2 2 5 5 5 2 Dynamin family DUF258 PF03193.11 CAM65355.1 - 0.0031 16.6 0.0 0.007 15.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 CAM65355.1 - 0.0041 17.1 0.0 0.056 13.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 CAM65355.1 - 0.014 15.9 3.6 0.57 10.6 0.0 3.7 4 0 0 4 4 4 0 Miro-like protein DUF2360 PF10152.4 CAM65356.1 - 6.2 7.0 8.1 84 3.4 5.6 2.3 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) MFS_1 PF07690.11 CAM65357.1 - 1.8e-25 89.4 42.8 2.2e-16 59.5 13.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1304 PF06993.7 CAM65357.1 - 0.72 9.5 8.1 6.8 6.4 0.5 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1304) ATP-synt_ab PF00006.20 CAM65359.2 - 6.5e-69 231.7 0.1 9.6e-69 231.1 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CAM65359.2 - 0.08 13.4 0.1 0.26 11.7 0.0 2.0 1 1 0 1 1 1 0 ATP synthase alpha/beta chain, C terminal domain His_kinase PF06580.8 CAM65359.2 - 0.086 12.7 2.4 6.4 6.7 0.0 2.5 2 0 0 2 2 2 0 Histidine kinase ATP-synt_ab PF00006.20 CAM65360.1 - 6.5e-69 231.7 0.1 9.6e-69 231.1 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CAM65360.1 - 0.08 13.4 0.1 0.26 11.7 0.0 2.0 1 1 0 1 1 1 0 ATP synthase alpha/beta chain, C terminal domain His_kinase PF06580.8 CAM65360.1 - 0.086 12.7 2.4 6.4 6.7 0.0 2.5 2 0 0 2 2 2 0 Histidine kinase ADH_zinc_N PF00107.21 CAM65362.1 - 5.8e-09 35.5 0.1 1.1e-08 34.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CAM65362.1 - 0.0063 16.2 0.1 0.019 14.7 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain LSM PF01423.17 CAM65364.2 - 1.5e-06 27.6 0.0 5.7e-06 25.7 0.0 1.9 1 1 0 1 1 1 1 LSM domain Pkinase PF00069.20 CAM65365.1 - 7.4e-70 235.0 0.0 8.4e-70 234.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM65365.1 - 1.3e-31 109.6 0.0 1.7e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CAM65365.1 - 0.00032 19.8 0.0 0.00051 19.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CAM65365.1 - 0.0044 16.7 0.0 0.022 14.5 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CAM65365.1 - 0.1 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Motile_Sperm PF00635.21 CAM65366.1 - 0.0023 17.5 0.0 0.018 14.7 0.0 2.4 3 0 0 3 3 3 1 MSP (Major sperm protein) domain NDUF_B5 PF09781.4 CAM65367.1 - 0.15 11.3 1.6 0.28 10.4 1.1 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit DUF1992 PF09350.5 CAM65368.1 - 0.14 12.0 0.1 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1992) DUF2106 PF09879.4 CAM65368.1 - 0.54 9.5 3.0 2.4 7.4 0.0 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2106) DEAD PF00270.24 CAM65369.1 - 4.3e-30 104.4 0.1 2.2e-15 56.5 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM65369.1 - 9.3e-22 76.6 0.1 1.8e-21 75.7 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAM65369.1 - 4.2e-05 23.4 0.0 0.0002 21.2 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CDC45 PF02724.9 CAM65369.1 - 0.1 10.6 1.6 0.15 10.0 1.1 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF3245 PF11595.3 CAM65369.1 - 0.35 11.1 11.8 3.2 7.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Nucleoplasmin PF03066.10 CAM65369.1 - 0.79 9.2 4.0 21 4.5 4.0 2.2 2 0 0 2 2 2 0 Nucleoplasmin PBP1_TM PF14812.1 CAM65369.1 - 1.7 9.0 13.6 0.29 11.4 6.1 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.7 CAM65369.1 - 2.9 5.7 8.0 5.2 4.8 5.6 1.3 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 CAM65369.1 - 6.9 5.8 9.7 11 5.1 6.7 1.2 1 0 0 1 1 1 0 NOA36 protein COG4 PF08318.7 CAM65370.1 - 3.5e-37 127.9 0.2 7.8e-34 116.9 0.0 2.9 3 0 0 3 3 3 2 COG4 transport protein Sec10 PF07393.6 CAM65370.1 - 0.0019 16.4 0.4 0.014 13.6 0.0 2.2 2 0 0 2 2 2 1 Exocyst complex component Sec10 RINT1_TIP1 PF04437.8 CAM65370.1 - 0.002 16.7 0.3 0.002 16.7 0.2 2.3 3 1 0 3 3 3 1 RINT-1 / TIP-1 family Surp PF01805.15 CAM65371.1 - 5.1e-09 35.6 0.0 8e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Surp module SR-25 PF10500.4 CAM65371.1 - 0.00014 21.4 16.2 0.00014 21.4 11.2 3.1 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein Dehydrin PF00257.14 CAM65371.1 - 1.7 8.9 16.0 0.043 14.1 6.1 2.0 2 0 0 2 2 2 0 Dehydrin ubiquitin PF00240.18 CAM65372.2 - 0.0028 17.0 0.0 0.0051 16.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Kinesin PF00225.18 CAM65373.1 - 1.1e-77 260.9 0.6 1.9e-77 260.2 0.4 1.4 1 0 0 1 1 1 1 Kinesin motor domain Phlebovirus_NSM PF07246.6 CAM65373.1 - 1.6 7.8 5.4 11 5.0 0.1 2.5 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M Ank_2 PF12796.2 CAM65374.2 - 8e-55 183.1 7.6 5.8e-11 42.5 0.0 10.9 8 4 3 11 11 11 9 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CAM65374.2 - 2.5e-39 132.9 16.7 2.3e-06 27.9 0.1 14.3 13 1 0 14 14 14 8 Ankyrin repeats (many copies) Ank PF00023.25 CAM65374.2 - 1.3e-37 125.7 41.7 6.6e-06 25.6 0.0 16.9 18 0 0 18 18 18 12 Ankyrin repeat Ank_5 PF13857.1 CAM65374.2 - 2e-35 119.9 27.8 4.8e-06 26.6 0.0 12.7 13 1 1 14 14 14 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 CAM65374.2 - 1.6e-34 114.4 23.7 0.0002 21.2 0.0 16.2 16 1 0 16 16 16 9 Ankyrin repeat LRR_4 PF12799.2 CAM65375.1 - 0.00093 18.7 0.7 0.0034 16.9 0.1 2.0 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CAM65375.1 - 0.0025 17.7 0.4 1.6 9.0 0.0 3.9 3 0 0 3 3 3 1 Leucine Rich repeat LRR_8 PF13855.1 CAM65375.1 - 0.0026 17.4 0.2 0.0078 15.9 0.1 1.7 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 CAM65375.1 - 0.017 15.0 0.6 0.39 10.9 0.2 3.2 2 1 0 2 2 2 0 Leucine Rich Repeat LRR_7 PF13504.1 CAM65375.1 - 0.28 11.5 5.4 2.8 8.5 0.1 4.2 4 0 0 4 4 4 0 Leucine rich repeat Nitroreductase PF00881.19 CAM65376.1 - 9.7e-31 106.8 0.0 1.6e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 Nitroreductase family Mtc PF03820.12 CAM65378.1 - 5.2e-71 238.8 0.1 5.9e-71 238.6 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier SHIPPO-rpt PF07004.7 CAM65379.2 - 2.6e-51 170.0 194.1 0.014 16.2 0.4 40.4 41 0 0 41 41 41 32 Sperm-tail PG-rich repeat Cyclin PF08613.6 CAM65381.1 - 1.3e-18 67.8 0.0 4.6e-18 66.0 0.0 2.0 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CAM65381.1 - 0.0041 16.6 0.0 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain DSPc PF00782.15 CAM65382.1 - 5.5e-18 64.8 0.2 3.6e-06 26.6 0.0 3.3 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain TMEM247 PF15444.1 CAM65383.1 - 0.091 12.5 1.7 0.18 11.6 1.2 1.5 1 0 0 1 1 1 0 Transmembrane protein 247 DUF605 PF04652.11 CAM65384.1 - 3.1e-75 253.9 31.3 1.2e-74 252.0 21.7 1.7 1 1 0 1 1 1 1 Vta1 like Wyosine_form PF08608.7 CAM65385.1 - 7.4e-21 74.0 1.7 9.7e-15 54.4 0.0 3.1 3 0 0 3 3 3 2 Wyosine base formation Radical_SAM PF04055.16 CAM65385.1 - 1.4e-20 74.1 0.0 2.3e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.20 CAM65385.1 - 7.6e-12 45.4 0.0 5.4e-11 42.6 0.0 2.2 2 0 0 2 2 2 1 Flavodoxin Kinesin PF00225.18 CAM65386.1 - 1.2e-81 273.9 0.0 1.7e-55 188.0 0.3 2.2 2 0 0 2 2 2 2 Kinesin motor domain Presenilin PF01080.12 CAM65386.1 - 0.89 8.3 2.8 0.48 9.1 0.0 1.9 2 0 0 2 2 2 0 Presenilin DUF3300 PF11737.3 CAM65388.1 - 0.21 10.8 1.2 0.21 10.8 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3300) MAM33 PF02330.11 CAM65389.2 - 1.7e-08 34.4 0.0 4.1e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial glycoprotein MbtH PF03621.8 CAM65389.2 - 0.24 10.7 1.3 17 4.8 0.1 2.5 2 0 0 2 2 2 0 MbtH-like protein zf-MYND PF01753.13 CAM65390.1 - 4.4e-11 42.4 12.6 4.4e-11 42.4 8.7 1.9 2 0 0 2 2 2 1 MYND finger DUF1688 PF07958.6 CAM65390.1 - 0.1 11.0 0.0 0.18 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1688) Got1 PF04178.7 CAM65391.1 - 9e-32 109.6 16.8 1.2e-31 109.2 11.6 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family 7tm_3 PF00003.17 CAM65391.1 - 0.00046 19.5 9.6 0.00046 19.5 6.6 1.6 1 1 1 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR Yip1 PF04893.12 CAM65391.1 - 0.3 10.5 13.2 0.37 10.2 9.1 1.2 1 0 0 1 1 1 0 Yip1 domain PNP_UDP_1 PF01048.15 CAM65393.1 - 1.1e-37 129.2 0.2 1.4e-37 128.8 0.2 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily zf-C2HC_2 PF13913.1 CAM65395.1 - 7e-14 51.0 10.1 7.6e-09 35.0 1.6 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2 PF00096.21 CAM65395.1 - 0.09 13.1 2.8 8.2 6.9 0.0 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CAM65395.1 - 0.24 11.7 1.5 1.9 8.9 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double domain Cys_rich_CPXG PF14255.1 CAM65395.1 - 0.25 11.2 1.1 16 5.4 0.1 2.3 2 0 0 2 2 2 0 Cysteine-rich CPXCG zf-FPG_IleRS PF06827.9 CAM65395.1 - 0.84 9.3 6.3 5.9 6.6 0.1 2.6 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Sgf11 PF08209.6 CAM65395.1 - 2.3 7.6 6.2 0.26 10.6 0.3 2.1 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) CPSF_A PF03178.10 CAM65399.2 - 1e-18 67.4 0.0 7.7e-14 51.5 0.0 3.3 3 0 0 3 3 3 2 CPSF A subunit region MMS1_N PF10433.4 CAM65399.2 - 9.4e-06 24.0 0.0 0.072 11.2 0.0 3.8 4 1 0 4 4 4 3 Mono-functional DNA-alkylating methyl methanesulfonate N-term NOA36 PF06524.7 CAM65399.2 - 1.4 8.1 4.0 2.3 7.3 2.8 1.2 1 0 0 1 1 1 0 NOA36 protein LRR_8 PF13855.1 CAM65400.1 - 9.9e-08 31.6 4.8 0.00017 21.2 0.4 2.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 CAM65400.1 - 1.1e-05 24.9 0.4 0.00018 21.0 0.3 2.5 2 1 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CAM65400.1 - 0.00011 21.7 0.5 12 6.4 0.0 5.0 5 0 0 5 5 5 1 Leucine Rich Repeat LRRNT_2 PF08263.7 CAM65401.1 - 0.16 11.9 2.1 0.36 10.8 1.5 1.6 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Flagellar_rod PF05149.7 CAM65402.1 - 8.7e-104 346.7 28.5 8.7e-104 346.7 19.8 2.1 3 0 0 3 3 3 1 Paraflagellar rod protein DUF3456 PF11938.3 CAM65402.1 - 4.8 7.1 11.7 0.028 14.4 1.3 2.3 3 0 0 3 3 3 0 TLR4 regulator and MIR-interacting MSAP UQ_con PF00179.21 CAM65403.1 - 3.3e-13 49.2 0.0 5.9e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Kinesin-relat_1 PF12711.2 CAM65404.1 - 0.009 16.3 0.3 0.12 12.7 0.1 2.4 2 0 0 2 2 2 1 Kinesin motor Peptidase_M28 PF04389.12 CAM65405.1 - 1.6e-15 57.2 2.9 0.00013 21.7 0.3 3.5 3 0 0 3 3 3 3 Peptidase family M28 Peptidase_M49 PF03571.10 CAM65406.1 - 2.1e-214 712.6 0.0 2.6e-214 712.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 DUF1930 PF09122.5 CAM65407.1 - 3e-39 132.6 0.1 5.6e-39 131.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1930) Rhodanese PF00581.15 CAM65407.1 - 5.2e-17 62.2 0.0 1.5e-07 31.7 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain Complex1_51K PF01512.12 CAM65408.1 - 8.6e-45 152.1 0.0 1.6e-44 151.2 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 CAM65408.1 - 1.9e-18 65.3 0.1 4.1e-18 64.2 0.0 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 CAM65408.1 - 3.1e-08 33.3 0.0 8.3e-08 32.0 0.0 1.8 1 0 0 1 1 1 1 SLBB domain Pet191_N PF10203.4 CAM65409.1 - 0.062 13.3 1.8 0.082 12.9 1.3 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 GCK PF07802.6 CAM65409.1 - 0.15 12.1 2.0 0.17 12.0 0.8 1.4 1 1 0 1 1 1 0 GCK domain CxxCxxCC PF03692.10 CAM65409.1 - 0.42 11.1 2.7 1.4 9.4 1.8 1.8 1 1 0 1 1 1 0 Putative zinc- or iron-chelating domain zf-C2HC5 PF06221.8 CAM65410.1 - 0.00038 20.1 1.5 0.00038 20.1 1.1 1.6 2 0 0 2 2 2 1 Putative zinc finger motif, C2HC5-type zf-C3HC4_3 PF13920.1 CAM65410.1 - 0.00042 19.9 6.7 0.00072 19.1 4.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAM65410.1 - 0.003 17.2 7.3 0.0053 16.4 5.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CAM65410.1 - 1.9 8.3 10.8 4.5 7.1 7.5 1.6 1 1 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 CAM65410.1 - 6.7 6.8 10.6 13 5.9 7.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UPF0020 PF01170.13 CAM65411.1 - 2.2e-14 53.4 0.0 3.7e-13 49.4 0.0 2.4 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 CAM65411.1 - 9.9e-10 38.4 0.1 3e-09 36.9 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 CAM65411.1 - 0.0018 17.8 0.0 0.013 15.0 0.0 2.1 2 0 0 2 2 2 1 DNA methylase N6_Mtase PF02384.11 CAM65411.1 - 0.0023 17.0 0.0 0.01 14.9 0.0 1.9 2 0 0 2 2 2 1 N-6 DNA Methylase Cren7 PF11520.3 CAM65412.1 - 0.024 14.2 0.0 0.056 13.0 0.0 1.6 1 0 0 1 1 1 0 Chromatin protein Cren7 Band_7 PF01145.20 CAM65414.1 - 1.8e-27 96.4 0.1 1.8e-27 96.4 0.1 1.7 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 CAM65414.1 - 0.057 12.9 0.1 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family IncA PF04156.9 CAM65415.1 - 3.1 7.3 5.9 1.2 8.7 1.2 2.0 2 0 0 2 2 2 0 IncA protein AFG1_ATPase PF03969.11 CAM65416.1 - 8.9e-80 268.2 0.3 8.1e-73 245.3 0.0 3.0 2 1 1 3 3 3 3 AFG1-like ATPase AAA_22 PF13401.1 CAM65416.1 - 0.0034 17.5 0.0 0.0065 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 CAM65416.1 - 0.023 13.7 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 CAM65416.1 - 0.076 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Lectin_leg-like PF03388.8 CAM65417.2 - 4.6e-12 45.5 0.0 2.6e-07 29.9 0.0 3.1 2 1 0 2 2 2 2 Legume-like lectin family PBP1_TM PF14812.1 CAM65417.2 - 0.094 13.0 6.5 0.25 11.6 4.5 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ELH PF02323.10 CAM65417.2 - 0.6 9.2 6.4 1.4 7.9 2.6 2.3 2 0 0 2 2 2 0 Egg-laying hormone precursor MORN PF02493.15 CAM65418.2 - 1.5e-26 90.5 32.7 7.9e-08 31.5 1.2 7.3 7 0 0 7 7 7 5 MORN repeat PBP1_TM PF14812.1 CAM65418.2 - 5.2 7.4 7.7 23 5.3 2.0 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Rad21_Rec8_N PF04825.8 CAM65419.1 - 6.2e-30 103.4 0.1 1.4e-29 102.2 0.1 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 CAM65419.1 - 3.1e-07 29.4 0.4 2.5e-06 26.5 0.0 2.4 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 CAM65419.1 - 0.00011 21.8 0.0 0.44 10.0 0.0 2.3 2 0 0 2 2 2 2 ScpA/B protein DUF4243 PF14027.1 CAM65419.1 - 0.33 10.3 3.5 0.7 9.2 2.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4243) Methyltransf_31 PF13847.1 CAM65420.1 - 5.4e-11 42.3 0.0 6.2e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAM65420.1 - 6.1e-10 39.6 0.0 4.7e-09 36.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CAM65420.1 - 1.3e-08 35.2 0.0 3.6e-08 33.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAM65420.1 - 2.6e-06 27.8 0.0 4.7e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 CAM65420.1 - 1.3e-05 24.9 0.0 0.14 11.7 0.0 2.1 2 0 0 2 2 2 2 Hypothetical methyltransferase NodS PF05401.6 CAM65420.1 - 2e-05 24.0 0.0 3.5e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Nodulation protein S (NodS) TPMT PF05724.6 CAM65420.1 - 2.6e-05 23.7 0.0 0.00063 19.2 0.0 2.2 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.1 CAM65420.1 - 9.7e-05 22.1 0.0 0.0002 21.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAM65420.1 - 0.00016 21.9 0.0 0.00035 20.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 CAM65420.1 - 0.0011 18.0 0.0 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.13 CAM65420.1 - 0.0032 16.6 0.0 0.021 13.9 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 CAM65420.1 - 0.0035 17.0 0.0 0.0056 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CAM65420.1 - 0.0045 17.0 0.0 0.027 14.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CAM65420.1 - 0.0099 15.2 0.0 0.041 13.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Pox_MCEL PF03291.11 CAM65420.1 - 0.035 12.9 0.0 0.075 11.8 0.0 1.6 1 1 0 1 1 1 0 mRNA capping enzyme EutQ PF06249.7 CAM65420.1 - 0.037 13.5 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ CMAS PF02353.15 CAM65420.1 - 0.039 13.0 0.0 0.07 12.1 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Spermine_synth PF01564.12 CAM65420.1 - 0.058 12.3 0.0 0.14 11.0 0.0 1.5 1 1 0 1 1 1 0 Spermine/spermidine synthase RRM_1 PF00076.17 CAM65421.1 - 1.3e-07 31.0 0.0 0.03 13.9 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM65421.1 - 0.0001 22.1 0.0 0.52 10.3 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) vATP-synt_AC39 PF01992.11 CAM65424.1 - 4.2e-62 210.2 0.1 4.8e-62 210.0 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit LRR_4 PF12799.2 CAM65425.1 - 6.1e-13 48.0 0.7 0.008 15.7 0.0 5.6 5 1 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CAM65425.1 - 3e-07 29.5 8.9 2.6 8.3 0.0 6.7 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_8 PF13855.1 CAM65425.1 - 1.5e-05 24.6 4.5 0.88 9.3 0.0 5.5 6 0 0 6 6 6 2 Leucine rich repeat LRR_6 PF13516.1 CAM65425.1 - 0.00076 19.2 9.1 0.22 11.7 0.0 5.8 6 0 0 6 6 6 1 Leucine Rich repeat ATG16 PF08614.6 CAM65425.1 - 0.012 15.5 3.5 0.024 14.4 2.4 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) LRR_9 PF14580.1 CAM65425.1 - 0.016 14.8 0.8 0.038 13.5 0.1 1.9 2 0 0 2 2 2 0 Leucine-rich repeat Filament PF00038.16 CAM65425.1 - 0.4 10.0 8.5 0.62 9.4 5.9 1.1 1 0 0 1 1 1 0 Intermediate filament protein LRR_7 PF13504.1 CAM65425.1 - 0.68 10.3 17.9 14 6.4 0.0 6.5 7 0 0 7 7 7 0 Leucine rich repeat ELO PF01151.13 CAM65426.1 - 7.5e-46 156.4 29.4 1.2e-45 155.7 20.4 1.3 1 0 0 1 1 1 1 GNS1/SUR4 family DUF346 PF03984.8 CAM65427.1 - 0.018 14.5 0.8 0.018 14.5 0.6 2.1 2 0 0 2 2 2 0 Repeat of unknown function (DUF346) Prefoldin_2 PF01920.15 CAM65429.1 - 2.6e-17 62.4 12.3 1.7e-16 59.8 8.5 2.0 1 1 0 1 1 1 1 Prefoldin subunit NAP PF00956.13 CAM65429.1 - 0.91 8.5 6.2 0.57 9.2 2.5 1.8 2 0 0 2 2 2 0 Nucleosome assembly protein (NAP) IncA PF04156.9 CAM65429.1 - 1.4 8.4 11.5 3 7.3 8.0 1.6 1 1 0 1 1 1 0 IncA protein DUF972 PF06156.8 CAM65429.1 - 1.8 8.9 9.5 4.1 7.7 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) ATG16 PF08614.6 CAM65429.1 - 2 8.1 13.2 5.1 6.8 0.4 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) APG6 PF04111.7 CAM65429.1 - 2 7.3 11.3 6.7 5.6 4.2 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF3847 PF12958.2 CAM65429.1 - 2.6 7.8 13.4 0.47 10.2 4.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3847) Spc24 PF08286.6 CAM65429.1 - 4.2 7.0 9.4 5.4 6.7 2.7 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Osmo_CC PF08946.5 CAM65429.1 - 4.8 7.2 13.2 0.24 11.4 1.5 3.6 2 2 1 3 3 3 0 Osmosensory transporter coiled coil OmpH PF03938.9 CAM65429.1 - 7.7 6.4 17.8 24 4.8 12.3 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Toxin_36 PF10550.4 CAM65429.1 - 10 7.5 7.2 11 7.4 0.4 3.7 3 1 0 3 3 3 0 Conantokin-G mollusc-toxin LRR_4 PF12799.2 CAM65430.1 - 2.1e-31 106.9 17.0 1.4e-07 30.9 0.3 6.6 4 1 3 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM65430.1 - 4.7e-20 71.0 25.5 2.6e-08 33.4 0.9 5.8 3 3 3 6 6 6 6 Leucine rich repeat LRR_9 PF14580.1 CAM65430.1 - 3.1e-15 56.1 5.0 1.5e-06 27.8 0.0 3.9 1 1 3 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.28 CAM65430.1 - 2.9e-13 47.8 24.6 0.34 11.1 0.1 10.3 10 1 1 11 11 11 5 Leucine Rich Repeat LRR_7 PF13504.1 CAM65430.1 - 4.8e-08 31.9 21.8 0.7 10.3 0.1 9.9 10 1 0 10 10 10 2 Leucine rich repeat LRR_6 PF13516.1 CAM65430.1 - 1.4e-07 30.8 24.3 0.22 11.6 0.1 9.3 5 2 5 10 10 10 4 Leucine Rich repeat Histone PF00125.19 CAM65432.1 - 2.6e-14 53.0 0.6 3.3e-14 52.7 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CAM65432.1 - 3.9e-05 23.6 0.6 6.1e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 CAM65432.1 - 0.0001 22.1 0.1 0.0001 22.1 0.1 1.4 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.8 CAM65432.1 - 0.0017 18.0 0.0 0.0022 17.6 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 CAM65432.1 - 0.0079 15.9 0.0 0.0084 15.8 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit FbpA PF05833.6 CAM65432.1 - 0.018 13.6 0.0 0.021 13.3 0.0 1.0 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) PCP_red PF08369.5 CAM65432.1 - 0.059 13.2 0.7 0.11 12.3 0.2 1.8 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit Coat_F PF07875.7 CAM65432.1 - 0.074 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Coat F domain LRR_4 PF12799.2 CAM65433.1 - 3.4e-24 83.9 0.9 0.016 14.8 0.0 8.7 7 2 2 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM65433.1 - 9.5e-12 44.5 11.5 0.021 14.5 0.0 6.6 5 1 3 8 8 8 7 Leucine rich repeat LRR_6 PF13516.1 CAM65433.1 - 9.9e-08 31.3 14.3 5.8 7.3 0.3 9.8 12 0 0 12 12 12 3 Leucine Rich repeat LRR_9 PF14580.1 CAM65433.1 - 0.028 13.9 2.5 0.6 9.6 0.1 3.5 2 1 1 3 3 3 0 Leucine-rich repeat LRR_1 PF00560.28 CAM65433.1 - 0.072 13.1 23.6 91 3.7 0.1 10.5 11 2 1 12 12 12 0 Leucine Rich Repeat LRR_7 PF13504.1 CAM65433.1 - 0.74 10.2 26.4 19 6.0 0.1 10.2 13 2 0 13 13 13 0 Leucine rich repeat WD40 PF00400.27 CAM65434.1 - 1.3e-63 208.7 27.6 6.9e-12 44.7 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CAM65434.1 - 5.9e-05 21.3 8.8 0.062 11.4 0.0 4.4 1 1 3 4 4 4 3 Nucleoporin Nup120/160 PB1 PF00564.19 CAM65434.1 - 0.049 13.2 0.0 0.3 10.7 0.0 2.3 2 0 0 2 2 2 0 PB1 domain MRP-L46 PF11788.3 CAM65435.1 - 2.7e-11 44.0 0.0 6.5e-11 42.8 0.0 1.7 1 1 0 1 1 1 1 39S mitochondrial ribosomal protein L46 PUF PF00806.14 CAM65436.1 - 7.4e-24 81.8 7.4 2.2e-05 23.6 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat Glycolytic PF00274.14 CAM65436.1 - 0.0063 14.9 0.1 0.0099 14.3 0.1 1.2 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I bZIP_1 PF00170.16 CAM65437.1 - 0.0046 16.8 9.6 0.012 15.5 0.6 3.1 3 0 0 3 3 3 2 bZIP transcription factor DUF2353 PF09789.4 CAM65437.1 - 0.019 14.2 10.7 0.36 10.0 3.5 2.6 2 1 0 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) HTH_5 PF01022.15 CAM65437.1 - 0.029 14.0 4.4 0.53 9.9 0.0 3.1 4 0 0 4 4 4 0 Bacterial regulatory protein, arsR family PPV_E1_N PF00524.13 CAM65437.1 - 0.04 14.1 1.0 0.04 14.1 0.7 2.5 2 1 2 4 4 4 0 E1 Protein, N terminal domain DASH_Spc34 PF08657.5 CAM65437.1 - 0.1 12.2 4.0 0.2 11.3 2.8 1.5 1 0 0 1 1 1 0 DASH complex subunit Spc34 DMPK_coil PF08826.5 CAM65437.1 - 0.29 11.0 0.2 0.29 11.0 0.1 3.3 3 0 0 3 3 3 0 DMPK coiled coil domain like DivIC PF04977.10 CAM65437.1 - 0.29 10.6 12.3 0.33 10.4 0.5 3.5 2 1 0 3 3 3 0 Septum formation initiator Nnf1 PF03980.9 CAM65437.1 - 0.53 10.2 6.5 4.4 7.3 0.6 3.0 2 1 0 2 2 2 0 Nnf1 Striatin PF08232.7 CAM65437.1 - 0.81 10.0 11.6 0.33 11.2 4.5 2.5 1 1 2 3 3 3 0 Striatin family bZIP_2 PF07716.10 CAM65437.1 - 4.1 7.3 15.4 0.85 9.4 0.5 3.5 3 0 0 3 3 3 0 Basic region leucine zipper ABC2_membrane PF01061.19 CAM65439.1 - 4e-34 117.6 18.3 4e-34 117.6 12.7 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 CAM65439.1 - 8.9e-22 77.8 0.0 1.5e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CAM65439.1 - 2.1e-07 31.1 0.0 0.00089 19.2 0.0 2.6 3 0 0 3 3 2 2 AAA domain SMC_N PF02463.14 CAM65439.1 - 0.00043 19.5 0.0 0.096 11.9 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CAM65439.1 - 0.0025 18.1 0.0 0.0039 17.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 CAM65439.1 - 0.0032 17.1 0.1 0.0083 15.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 CAM65439.1 - 0.005 16.8 0.1 0.0094 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 CAM65439.1 - 0.0062 15.9 0.2 0.016 14.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CAM65439.1 - 0.0068 17.2 0.0 0.013 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF87 PF01935.12 CAM65439.1 - 0.0087 15.9 0.3 0.016 15.0 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF87 DUF258 PF03193.11 CAM65439.1 - 0.01 15.0 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 CAM65439.1 - 0.021 14.3 0.2 0.048 13.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 CAM65439.1 - 0.024 14.0 0.6 0.049 13.0 0.1 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_10 PF12846.2 CAM65439.1 - 0.029 13.8 0.0 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_19 PF13245.1 CAM65439.1 - 0.044 13.5 0.2 0.12 12.0 0.2 1.7 1 0 0 1 1 1 0 Part of AAA domain NTPase_1 PF03266.10 CAM65439.1 - 0.061 13.0 0.0 0.65 9.6 0.0 2.2 2 0 0 2 2 2 0 NTPase AAA_22 PF13401.1 CAM65439.1 - 0.07 13.2 0.1 0.33 11.0 0.0 2.1 3 0 0 3 3 2 0 AAA domain AAA_15 PF13175.1 CAM65439.1 - 0.085 11.8 0.0 7 5.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain cobW PF02492.14 CAM65439.1 - 0.093 12.1 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 CAM65439.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Thymidylate_kin PF02223.12 CAM65439.1 - 0.14 11.4 0.1 5.3 6.3 0.0 2.5 2 1 0 2 2 2 0 Thymidylate kinase SbcCD_C PF13558.1 CAM65439.1 - 0.15 12.0 0.1 0.56 10.1 0.0 2.1 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit UPF0079 PF02367.12 CAM65439.1 - 0.19 11.3 0.2 1.5 8.4 0.1 2.4 2 1 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ABC2_membrane PF01061.19 CAM65440.1 - 6.8e-36 123.4 16.1 6.8e-36 123.4 11.2 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 CAM65440.1 - 1e-21 77.6 0.0 1.5e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CAM65440.1 - 2.6e-07 30.8 0.0 0.0009 19.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 CAM65440.1 - 0.00046 19.4 0.0 0.097 11.8 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CAM65440.1 - 0.0026 18.0 0.0 0.004 17.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 CAM65440.1 - 0.0032 17.1 0.1 0.0084 15.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 CAM65440.1 - 0.005 16.8 0.1 0.0095 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 CAM65440.1 - 0.0062 15.9 0.2 0.016 14.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CAM65440.1 - 0.0072 17.1 0.0 0.013 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF87 PF01935.12 CAM65440.1 - 0.009 15.8 0.3 0.016 15.0 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF87 DUF258 PF03193.11 CAM65440.1 - 0.01 15.0 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 CAM65440.1 - 0.023 14.2 0.2 0.048 13.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 CAM65440.1 - 0.026 13.9 0.1 0.05 13.0 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_10 PF12846.2 CAM65440.1 - 0.03 13.7 0.0 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_19 PF13245.1 CAM65440.1 - 0.041 13.6 0.2 0.13 12.0 0.2 1.8 1 0 0 1 1 1 0 Part of AAA domain NTPase_1 PF03266.10 CAM65440.1 - 0.056 13.1 0.0 0.66 9.6 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA_22 PF13401.1 CAM65440.1 - 0.075 13.1 0.1 0.34 11.0 0.0 2.0 3 0 0 3 3 2 0 AAA domain AAA_15 PF13175.1 CAM65440.1 - 0.09 11.8 0.0 7.1 5.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain cobW PF02492.14 CAM65440.1 - 0.097 12.1 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 CAM65440.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Thymidylate_kin PF02223.12 CAM65440.1 - 0.16 11.3 0.1 5.3 6.3 0.0 2.5 2 1 0 2 2 2 0 Thymidylate kinase CytochromB561_N PF09786.4 CAM65442.1 - 0.001 17.6 0.1 0.0033 15.9 0.1 1.8 1 1 0 1 1 1 1 Cytochrome B561, N terminal Pro_isomerase PF00160.16 CAM65443.1 - 2e-48 164.5 0.1 2.3e-48 164.3 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF1768 PF08719.6 CAM65444.1 - 1.1e-32 112.9 0.0 1.3e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Proteasome PF00227.21 CAM65445.1 - 1e-30 106.4 0.0 1.4e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit VKOR PF07884.9 CAM65446.1 - 0.1 12.4 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Vitamin K epoxide reductase family NRPS PF08415.5 CAM65446.1 - 0.15 11.8 0.2 0.29 10.9 0.1 1.7 1 1 1 2 2 2 0 Nonribosomal peptide synthase HD PF01966.17 CAM65447.1 - 7.8e-14 51.7 0.3 7.8e-14 51.7 0.2 1.9 2 0 0 2 2 2 1 HD domain HDOD PF08668.7 CAM65447.1 - 0.00045 19.5 0.0 0.0008 18.7 0.0 1.3 1 0 0 1 1 1 1 HDOD domain Trm112p PF03966.11 CAM65448.1 - 1.3e-07 31.8 0.0 4.8e-07 30.0 0.0 1.8 1 1 0 1 1 1 1 Trm112p-like protein zinc_ribbon_5 PF13719.1 CAM65448.1 - 0.031 13.8 0.2 0.031 13.8 0.1 1.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CAM65448.1 - 0.043 13.4 0.2 0.043 13.4 0.1 1.8 2 0 0 2 2 2 0 zinc-ribbon domain Kinesin PF00225.18 CAM65449.2 - 5e-71 239.1 0.0 6.7e-71 238.7 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain PdxJ PF03740.8 CAM65449.2 - 0.14 11.2 0.2 0.25 10.4 0.1 1.3 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthesis protein PdxJ FHA PF00498.21 CAM65452.1 - 5.2e-10 39.2 0.0 1.7e-08 34.4 0.0 2.4 2 0 0 2 2 2 1 FHA domain DUF4490 PF14892.1 CAM65453.1 - 0.00043 19.8 0.4 0.00082 18.9 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) Leu_zip PF15294.1 CAM65456.1 - 1.8e-09 37.1 12.2 1.4e-05 24.4 1.8 2.1 1 1 1 2 2 2 2 Leucine zipper Atg14 PF10186.4 CAM65456.1 - 0.012 14.6 10.2 0.013 14.4 6.4 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ACCA PF03255.9 CAM65456.1 - 0.14 11.7 2.4 0.7 9.4 0.3 2.2 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit IncA PF04156.9 CAM65456.1 - 0.28 10.7 8.6 0.44 10.1 6.0 1.3 1 0 0 1 1 1 0 IncA protein Occludin_ELL PF07303.8 CAM65456.1 - 0.45 11.2 7.0 2.9 8.6 1.5 2.4 1 1 1 2 2 2 0 Occludin homology domain Mnd1 PF03962.10 CAM65456.1 - 0.97 9.0 11.4 0.58 9.7 5.4 1.9 1 1 1 2 2 2 0 Mnd1 family Rotamase PF00639.16 CAM65456.1 - 1.4 9.7 3.6 1.5 9.6 0.5 2.2 1 1 1 2 2 2 0 PPIC-type PPIASE domain HAUS-augmin3 PF14932.1 CAM65456.1 - 1.6 7.8 12.8 4 6.5 0.5 2.4 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Filament PF00038.16 CAM65456.1 - 1.6 8.1 15.1 0.18 11.2 7.2 1.8 2 1 0 2 2 2 0 Intermediate filament protein UPF0449 PF15136.1 CAM65456.1 - 2.2 8.5 7.6 0.72 10.0 1.2 2.6 1 1 2 3 3 3 0 Uncharacterised protein family UPF0449 GAS PF13851.1 CAM65456.1 - 5.6 6.0 12.1 4.9 6.2 4.0 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.6 CAM65456.1 - 5.9 6.3 7.4 9.6 5.6 1.7 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 APG6 PF04111.7 CAM65456.1 - 9.3 5.1 10.6 16 4.4 7.4 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 MxiH PF09392.5 CAM65456.1 - 10 6.8 15.6 2.6 8.6 4.7 2.9 1 1 1 2 2 2 0 Type III secretion needle MxiH like XRN_N PF03159.13 CAM65457.2 - 3.9e-91 304.6 0.0 6.6e-91 303.9 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus FHA PF00498.21 CAM65459.1 - 0.0039 17.2 0.0 0.0077 16.3 0.0 1.4 1 0 0 1 1 1 1 FHA domain RNase_H PF00075.19 CAM65460.1 - 2.3e-24 86.2 0.5 2.3e-22 79.7 0.3 2.9 1 1 0 1 1 1 1 RNase H zf-MYND PF01753.13 CAM65461.1 - 2.5e-12 46.4 14.5 2.5e-12 46.4 10.1 1.9 2 0 0 2 2 2 1 MYND finger DUF4599 PF15371.1 CAM65461.1 - 0.045 13.8 2.2 1.9 8.6 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4599) zf-HIT PF04438.11 CAM65461.1 - 3.8 7.2 19.7 0.13 11.9 4.8 2.8 3 0 0 3 3 3 0 HIT zinc finger BT1 PF03092.11 CAM65462.1 - 1.5e-147 491.7 7.5 1.8e-147 491.5 5.2 1.0 1 0 0 1 1 1 1 BT1 family TPR_11 PF13414.1 CAM65464.1 - 7.8e-06 25.4 6.7 2.5e-05 23.8 3.4 2.5 1 1 1 2 2 2 1 TPR repeat TPR_2 PF07719.12 CAM65464.1 - 0.00088 19.0 9.9 0.71 9.9 0.6 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 CAM65464.1 - 0.0069 17.0 4.2 0.0069 17.0 2.9 4.8 5 1 2 7 7 7 2 Tetratricopeptide repeat Sel1 PF08238.7 CAM65464.1 - 0.18 12.4 6.3 0.52 11.0 0.2 2.7 2 0 0 2 2 2 0 Sel1 repeat TPR_1 PF00515.23 CAM65464.1 - 0.41 10.3 4.3 2 8.1 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 CAM65464.1 - 1.3 9.8 20.3 2.2 9.1 0.7 5.1 2 1 2 4 4 4 0 Tetratricopeptide repeat Peptidase_S9 PF00326.16 CAM65465.1 - 2.3e-33 115.2 0.0 3.9e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.10 CAM65465.1 - 3.5e-25 88.4 0.0 8.7e-25 87.1 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain 3Beta_HSD PF01073.14 CAM65466.1 - 3.7e-37 127.5 0.0 4.6e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CAM65466.1 - 4.5e-28 98.2 0.0 5.8e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CAM65466.1 - 6.4e-17 61.3 0.0 7e-11 41.5 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 CAM65466.1 - 2.1e-15 57.2 0.0 2.9e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 CAM65466.1 - 2.2e-10 39.8 0.0 3.3e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 CAM65466.1 - 2.5e-08 33.1 0.0 4.2e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 CAM65466.1 - 4.4e-07 29.3 0.0 6.4e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 CAM65466.1 - 1.1e-05 25.4 0.1 4.7e-05 23.3 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CAM65466.1 - 0.0013 18.4 0.1 0.0036 16.9 0.1 1.8 2 1 0 2 2 2 1 KR domain Saccharop_dh PF03435.13 CAM65466.1 - 0.11 11.4 0.1 0.17 10.8 0.0 1.4 1 1 0 1 1 1 0 Saccharopine dehydrogenase Gln-synt_C PF00120.19 CAM65468.1 - 5.5e-47 160.0 0.0 7.5e-47 159.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 CAM65468.1 - 3.9e-16 58.3 0.0 7.6e-16 57.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain zf-CCCH PF00642.19 CAM65469.1 - 7.8e-07 28.6 1.5 1.6e-06 27.5 1.0 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CAM65469.1 - 0.012 15.5 1.9 0.012 15.5 1.3 2.3 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Ribosomal_L19e PF01280.15 CAM65472.1 - 3.8e-59 198.6 12.4 3.8e-59 198.6 8.6 2.1 1 1 1 2 2 2 1 Ribosomal protein L19e OrfB_Zn_ribbon PF07282.6 CAM65473.1 - 0.066 12.8 0.5 0.17 11.5 0.3 1.7 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Ribosomal_L19e PF01280.15 CAM65474.1 - 3.5e-59 198.8 12.4 3.5e-59 198.8 8.6 2.1 1 1 1 2 2 2 1 Ribosomal protein L19e APG6 PF04111.7 CAM65474.1 - 6 5.8 9.5 8 5.4 6.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Kinesin PF00225.18 CAM65476.1 - 3.4e-10 39.1 4.3 0.00012 20.8 0.0 3.1 3 0 0 3 3 3 2 Kinesin motor domain TMF_DNA_bd PF12329.3 CAM65476.1 - 0.008 15.9 12.9 0.013 15.3 7.1 2.4 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.1 CAM65476.1 - 0.023 13.1 6.6 0.033 12.6 4.6 1.2 1 0 0 1 1 1 0 AAA domain DUF948 PF06103.6 CAM65476.1 - 0.082 12.7 0.4 1.2 8.9 0.0 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Mnd1 PF03962.10 CAM65476.1 - 0.83 9.2 23.4 2 8.0 5.5 2.6 1 1 1 2 2 2 0 Mnd1 family V_ATPase_I PF01496.14 CAM65476.1 - 5.8 4.6 10.5 8.8 4.0 7.1 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.7 CAM65476.1 - 8 6.2 10.0 0.93 9.3 1.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) TPR_11 PF13414.1 CAM65477.1 - 2.4e-06 27.0 3.0 1.6e-05 24.4 0.1 2.5 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.1 CAM65477.1 - 2.7e-06 27.2 0.5 0.0001 22.1 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 CAM65477.1 - 0.00077 19.3 2.8 0.011 15.6 0.0 3.9 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 CAM65477.1 - 0.00091 18.7 2.7 0.028 14.0 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 CAM65477.1 - 0.0077 16.0 0.1 0.055 13.3 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 CAM65477.1 - 0.014 15.1 0.1 1.1 9.2 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 CAM65477.1 - 0.081 13.2 1.6 0.39 11.0 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat NAD_kinase PF01513.16 CAM65479.1 - 3.2e-14 52.3 0.0 5.7e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase Cnd2 PF05786.9 CAM65480.1 - 3.5e-22 78.7 10.4 1.7e-13 50.0 0.2 3.2 3 0 0 3 3 3 2 Condensin complex subunit 2 DUF3870 PF12986.2 CAM65480.1 - 0.19 12.0 0.0 0.43 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) SpoU_methylase PF00588.14 CAM65483.1 - 1.3e-15 57.5 0.0 2.6e-09 37.1 0.0 3.1 3 0 0 3 3 3 2 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 CAM65483.1 - 6.5e-05 23.0 0.0 0.0005 20.1 0.0 2.2 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding MAGE_N PF12440.3 CAM65483.1 - 0.0032 17.7 2.3 0.0032 17.7 1.6 3.3 3 0 0 3 3 3 1 Melanoma associated antigen family N terminal U-box PF04564.10 CAM65484.2 - 2.7e-12 46.4 0.0 5.6e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 U-box domain LRR_4 PF12799.2 CAM65485.1 - 3.8e-17 61.4 2.5 0.059 13.0 0.0 9.1 9 1 1 10 10 10 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CAM65485.1 - 1e-07 31.2 14.5 4.8 7.5 0.0 10.2 12 1 0 12 12 12 3 Leucine Rich repeat LRR_8 PF13855.1 CAM65485.1 - 4.9e-06 26.1 4.8 2.2 8.0 0.5 7.0 7 0 0 7 7 7 1 Leucine rich repeat LRR_1 PF00560.28 CAM65485.1 - 0.054 13.5 15.7 1e+02 3.5 0.0 10.2 12 2 1 13 13 13 0 Leucine Rich Repeat PDT PF00800.13 CAM65486.1 - 0.03 13.8 0.2 0.05 13.1 0.2 1.3 1 0 0 1 1 1 0 Prephenate dehydratase Maf_N PF08383.6 CAM65486.1 - 0.046 13.2 0.1 0.046 13.2 0.1 2.2 2 0 0 2 2 2 0 Maf N-terminal region DUF4557 PF15101.1 CAM65488.2 - 4.7 6.9 9.4 13 5.5 6.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) dUTPase_2 PF08761.6 CAM65489.1 - 7.2e-40 136.8 0.0 1e-39 136.2 0.0 1.2 1 0 0 1 1 1 1 dUTPase Ribosomal_L23 PF00276.15 CAM65490.1 - 1.1e-20 73.2 2.6 1.1e-20 73.2 1.8 2.3 2 1 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.8 CAM65490.1 - 1.5e-11 44.1 13.9 1.5e-11 44.1 9.7 2.2 2 1 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Late_protein_L2 PF00513.13 CAM65490.1 - 0.002 17.0 1.2 0.0023 16.8 0.9 1.0 1 0 0 1 1 1 1 Late Protein L2 TusA PF01206.12 CAM65490.1 - 0.017 14.6 0.1 0.036 13.6 0.1 1.6 1 0 0 1 1 1 0 Sulfurtransferase TusA P2 PF07194.6 CAM65490.1 - 0.039 13.8 0.4 0.071 12.9 0.3 1.4 1 0 0 1 1 1 0 P2 response regulator binding domain PHD PF00628.24 CAM65493.1 - 9.5e-05 22.0 1.0 9.5e-05 22.0 0.7 2.0 2 0 0 2 2 2 1 PHD-finger DUF4206 PF13901.1 CAM65493.1 - 0.18 11.3 0.6 0.3 10.6 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) zf-RING_2 PF13639.1 CAM65493.1 - 1.7 8.5 7.8 0.85 9.5 2.1 2.4 2 0 0 2 2 2 0 Ring finger domain Pro_CA PF00484.14 CAM65494.1 - 9e-41 139.4 1.4 3.5e-40 137.5 1.0 1.8 1 1 0 1 1 1 1 Carbonic anhydrase Rsc14 PF08586.5 CAM65494.1 - 0.045 14.2 0.0 0.7 10.3 0.0 2.2 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit DUF89 PF01937.14 CAM65495.1 - 2.8e-40 138.2 0.2 8.9e-22 77.3 0.0 4.4 4 0 0 4 4 4 4 Protein of unknown function DUF89 Put_Phosphatase PF06888.7 CAM65495.1 - 3.5e-33 114.7 3.7 1.3e-14 53.9 0.0 3.3 2 1 1 3 3 3 3 Putative Phosphatase HAD PF12710.2 CAM65495.1 - 0.00018 21.7 0.1 0.0026 17.9 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CAM65495.1 - 0.035 14.3 0.1 0.22 11.7 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Pkinase PF00069.20 CAM65497.2 - 1.1e-46 159.0 0.0 2.9e-46 157.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM65497.2 - 1.2e-30 106.4 0.0 1.6e-22 79.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase FHA PF00498.21 CAM65497.2 - 5.2e-09 36.0 0.1 1.1e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 FHA domain PAS_9 PF13426.1 CAM65497.2 - 0.00057 20.2 0.0 0.78 10.1 0.0 2.5 2 0 0 2 2 2 2 PAS domain Kinase-like PF14531.1 CAM65497.2 - 0.00066 18.7 0.1 0.0016 17.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like PAS PF00989.19 CAM65497.2 - 0.0015 18.3 0.0 0.17 11.6 0.0 2.5 2 0 0 2 2 2 1 PAS fold Kdo PF06293.9 CAM65497.2 - 0.13 11.2 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_8 PF13188.1 CAM65497.2 - 0.17 11.8 0.0 16 5.5 0.0 2.5 2 0 0 2 2 2 0 PAS domain RIO1 PF01163.17 CAM65497.2 - 0.53 9.6 0.0 0.87 8.9 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Prenyltrans PF00432.16 CAM65498.1 - 2.9e-23 81.1 17.3 2.3e-09 36.6 0.0 6.1 6 1 0 6 6 6 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 CAM65498.1 - 1.5e-22 79.6 7.2 3.5e-09 36.6 0.1 5.0 3 1 3 6 6 6 4 Prenyltransferase-like Prenyltrans_2 PF13249.1 CAM65498.1 - 2.7e-21 76.1 0.4 3e-10 40.5 0.1 5.4 3 1 2 5 5 5 4 Prenyltransferase-like Pec_lyase PF09492.5 CAM65498.1 - 3.1e-08 33.1 0.2 0.075 12.1 0.0 4.8 3 1 2 5 5 5 3 Pectic acid lyase NDUF_B7 PF05676.8 CAM65501.1 - 0.0006 19.1 3.5 0.001 18.4 2.4 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 CAM65501.1 - 0.0014 18.4 5.2 0.0024 17.6 3.6 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 CAM65501.1 - 0.44 10.5 5.0 0.76 9.7 3.4 1.4 1 0 0 1 1 1 0 CHCH domain Ctf8 PF09696.5 CAM65502.1 - 1.3e-06 28.2 0.0 0.017 14.9 0.0 3.1 3 0 0 3 3 3 3 Ctf8 DUF1908 PF08926.6 CAM65502.1 - 0.77 8.4 5.6 1.5 7.4 3.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) zf-CCHC_2 PF13696.1 CAM65503.1 - 0.13 11.7 8.0 4.1 6.9 2.7 3.0 2 0 0 2 2 2 0 Zinc knuckle zf-ribbon_3 PF13248.1 CAM65503.1 - 2.7 7.2 6.7 5.1 6.4 1.0 2.8 2 0 0 2 2 2 0 zinc-ribbon domain Ank_5 PF13857.1 CAM65504.1 - 2.9e-10 40.0 3.0 0.00098 19.2 0.1 3.8 2 2 2 4 4 4 2 Ankyrin repeats (many copies) C2 PF00168.25 CAM65504.1 - 2.2e-09 37.0 0.0 3.9e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain Ank_2 PF12796.2 CAM65504.1 - 3.7e-09 36.8 0.0 1.8e-08 34.6 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 CAM65504.1 - 1.7e-08 33.8 0.1 0.0039 16.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 CAM65504.1 - 4.4e-07 30.2 0.6 0.002 18.5 0.0 3.1 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CAM65504.1 - 3.4e-05 23.6 0.0 0.14 12.4 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat YEATS PF03366.11 CAM65506.2 - 6.5e-16 57.8 0.0 2.3e-15 56.0 0.0 1.8 1 1 0 1 1 1 1 YEATS family Nop14 PF04147.7 CAM65506.2 - 1.9 6.2 12.4 3 5.6 8.6 1.1 1 0 0 1 1 1 0 Nop14-like family PALP PF00291.20 CAM65507.1 - 3.2e-58 197.3 0.6 3.6e-58 197.2 0.4 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme HlyIII PF03006.15 CAM65509.2 - 2.1e-22 79.6 0.0 1.7e-14 53.7 0.0 2.4 2 1 0 2 2 2 2 Haemolysin-III related RRM_1 PF00076.17 CAM65511.2 - 7.3e-25 86.4 0.0 4.3e-12 45.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM65511.2 - 8.9e-20 70.4 0.0 1.2e-08 34.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM65511.2 - 2.8e-06 27.0 0.0 0.022 14.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HIM1 PF08732.5 CAM65512.1 - 8.7 4.6 0.0 13 4.0 0.0 1.1 1 0 0 1 1 1 0 HIM1 Glyoxalase PF00903.20 CAM65516.1 - 0.0076 16.2 0.0 0.018 15.0 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily RmuC PF02646.11 CAM65516.1 - 0.02 13.7 0.7 0.02 13.7 0.5 2.0 2 0 0 2 2 2 0 RmuC family Cwf_Cwc_15 PF04889.7 CAM65516.1 - 0.032 13.9 3.9 0.058 13.1 2.7 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Glyoxalase_2 PF12681.2 CAM65516.1 - 0.049 14.2 0.4 0.17 12.5 0.0 2.2 2 2 0 2 2 2 0 Glyoxalase-like domain DUF4618 PF15397.1 CAM65516.1 - 0.067 12.5 1.8 8 5.7 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) DUF2721 PF11026.3 CAM65516.1 - 1 8.9 9.1 0.14 11.8 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) CENP-Q PF13094.1 CAM65516.1 - 1.2 9.1 13.0 3.5 7.6 0.5 2.5 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit SNARE PF05739.14 CAM65516.1 - 3.2 7.4 11.7 0.4 10.3 3.8 2.3 2 0 0 2 2 2 0 SNARE domain YlqD PF11068.3 CAM65516.1 - 4.1 7.4 7.5 3.6 7.6 0.1 2.8 3 0 0 3 3 3 0 YlqD protein LNS2 PF08235.8 CAM65517.1 - 8.2e-54 181.4 0.0 1.2e-53 180.8 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 CAM65517.1 - 6.6e-18 64.3 0.0 1.4e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 CAM65517.1 - 0.041 13.2 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) AF1Q PF15017.1 CAM65517.1 - 0.71 9.8 8.0 0.23 11.4 0.1 3.2 3 0 0 3 3 3 0 Drug resistance and apoptosis regulator Rbsn PF11464.3 CAM65517.1 - 2.1 7.9 1.8 17 5.0 0.3 2.5 2 0 0 2 2 2 0 Rabenosyn Rab binding domain APC_CDC26 PF10471.4 CAM65518.1 - 0.072 13.8 0.9 0.23 12.2 0.6 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 MAGE_N PF12440.3 CAM65518.1 - 0.47 10.7 10.1 0.1 12.9 3.2 2.3 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal EF-hand_1 PF00036.27 CAM65519.1 - 0.052 12.8 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.1 CAM65519.1 - 0.075 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.1 CAM65519.1 - 0.51 10.3 0.0 1.2 9.1 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain 7tm_7 PF08395.7 CAM65519.1 - 3.8 6.4 2.3 7 5.5 1.6 1.3 1 0 0 1 1 1 0 7tm Chemosensory receptor Thymidylat_synt PF00303.14 CAM65520.2 - 1.4e-110 368.5 0.0 1.7e-110 368.2 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.14 CAM65520.2 - 2e-25 89.2 0.0 1.4e-24 86.4 0.0 2.3 1 1 0 1 1 1 1 Dihydrofolate reductase Spo12 PF05032.7 CAM65520.2 - 0.085 12.4 0.0 0.22 11.1 0.0 1.7 2 0 0 2 2 2 0 Spo12 family Methyltransf_18 PF12847.2 CAM65521.1 - 1.2e-10 41.9 0.0 2.5e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CAM65521.1 - 3.4e-09 36.2 0.0 6.6e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 CAM65521.1 - 6e-06 25.8 0.0 9.3e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 CAM65521.1 - 9e-06 25.1 0.0 2.7e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 CAM65521.1 - 1.4e-05 25.1 0.0 3.5e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 CAM65521.1 - 5.3e-05 22.6 0.0 8.8e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.11 CAM65521.1 - 8.1e-05 22.2 0.0 0.00015 21.4 0.0 1.5 2 0 0 2 2 2 1 Met-10+ like-protein PCMT PF01135.14 CAM65521.1 - 0.0006 19.4 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PRMT5 PF05185.11 CAM65521.1 - 0.00092 18.2 0.0 0.0012 17.8 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_31 PF13847.1 CAM65521.1 - 0.0018 17.9 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 CAM65521.1 - 0.0019 17.2 0.0 0.0031 16.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase CMAS PF02353.15 CAM65521.1 - 0.0025 16.9 0.0 0.0038 16.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 CAM65521.1 - 0.011 16.1 0.0 0.032 14.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 CAM65521.1 - 0.012 16.0 0.0 0.045 14.2 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 CAM65521.1 - 0.02 15.2 0.0 0.043 14.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Acyl-CoA_dh_1 PF00441.19 CAM65522.1 - 8.5e-49 165.4 3.0 1.3e-48 164.8 2.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CAM65522.1 - 3.2e-27 95.3 0.3 1e-26 93.7 0.2 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CAM65522.1 - 8e-22 76.5 1.0 2.3e-21 75.0 0.3 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CAM65522.1 - 4.3e-21 75.5 1.0 6.7e-21 74.9 0.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 CAM65522.1 - 5.4e-05 22.7 0.4 0.00028 20.3 0.3 2.1 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal PcrB PF01884.12 CAM65522.1 - 0.091 12.0 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 PcrB family PP2C PF00481.16 CAM65524.1 - 1.9e-24 86.4 0.2 5.6e-16 58.6 0.0 3.8 4 0 0 4 4 4 3 Protein phosphatase 2C SpoIIE PF07228.7 CAM65524.1 - 0.0061 16.2 0.1 0.045 13.4 0.0 2.4 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PTH2 PF01981.11 CAM65525.1 - 9.8e-48 160.6 0.2 1.1e-47 160.4 0.1 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Oxidored_FMN PF00724.15 CAM65527.1 - 2.8e-46 158.1 0.0 3.6e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.9 CAM65527.1 - 7.2e-11 42.3 0.0 2.1e-10 40.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CAM65527.1 - 6.7e-10 38.8 0.0 2.3e-09 37.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CAM65527.1 - 3.6e-08 33.7 0.3 0.00054 20.0 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CAM65527.1 - 4.2e-08 32.5 0.0 9.6e-08 31.3 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 CAM65527.1 - 9.9e-08 32.2 0.7 0.00035 20.9 0.4 3.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CAM65527.1 - 1.3e-07 30.8 0.0 2e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 CAM65527.1 - 1.3e-06 27.1 1.5 4.6e-06 25.3 0.1 2.4 2 1 1 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.2 CAM65527.1 - 1.5e-06 27.5 1.1 5.3e-06 25.7 0.7 1.7 1 1 1 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 CAM65527.1 - 0.00039 19.5 0.1 0.0008 18.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 CAM65527.1 - 0.00095 18.1 0.2 0.0014 17.5 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.19 CAM65527.1 - 0.003 16.6 0.0 0.0046 16.0 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 CAM65527.1 - 0.0065 16.1 0.0 0.031 13.9 0.0 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 CAM65527.1 - 0.0074 15.7 0.1 0.029 13.8 0.1 2.0 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 CAM65527.1 - 0.0096 15.0 0.1 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_Gly3P_dh_N PF01210.18 CAM65527.1 - 0.013 15.1 0.1 0.036 13.8 0.1 1.7 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.1 CAM65527.1 - 0.037 14.2 0.2 0.68 10.2 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 CAM65527.1 - 0.059 12.7 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_10 PF13460.1 CAM65527.1 - 0.06 13.3 3.1 0.56 10.1 0.3 3.0 3 0 0 3 3 3 0 NADH(P)-binding NAD_binding_9 PF13454.1 CAM65527.1 - 0.082 12.6 0.1 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding ThiF PF00899.16 CAM65527.1 - 0.28 11.0 3.5 0.84 9.4 0.3 3.0 3 1 0 3 3 3 0 ThiF family TLD PF07534.11 CAM65528.1 - 1.4e-08 34.8 0.0 6.4e-05 22.9 0.0 3.2 3 0 0 3 3 3 3 TLD SIS PF01380.17 CAM65529.1 - 3.4e-48 162.5 1.0 3.9e-26 91.2 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.1 CAM65529.1 - 1.3e-17 63.9 0.0 4.1e-17 62.3 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 CAM65529.1 - 2.3e-16 59.4 0.2 7.4e-12 44.6 0.0 2.4 2 1 0 2 2 2 2 Glutamine amidotransferases class-II GATase_7 PF13537.1 CAM65529.1 - 6.5e-11 42.0 0.0 1.5e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain SIS_2 PF13580.1 CAM65529.1 - 1.6e-05 24.6 0.1 0.0077 15.9 0.0 2.8 3 0 0 3 3 3 2 SIS domain GATase_4 PF13230.1 CAM65529.1 - 1.8e-05 23.5 0.1 3.9e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II LuxQ-periplasm PF09308.5 CAM65529.1 - 0.036 13.4 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 LuxQ, periplasmic Mob1_phocein PF03637.12 CAM65530.1 - 2.5e-64 216.1 0.3 2.9e-64 215.9 0.2 1.0 1 0 0 1 1 1 1 Mob1/phocein family DUF3883 PF13020.1 CAM65531.2 - 9e-14 50.9 0.0 2.4e-13 49.6 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3883) WD40 PF00400.27 CAM65533.1 - 2.5e-06 27.1 0.4 0.0045 16.8 0.0 3.1 2 0 0 2 2 2 2 WD domain, G-beta repeat Claudin_2 PF13903.1 CAM65534.1 - 0.37 10.4 2.8 1.5 8.5 0.5 2.0 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction SET PF00856.23 CAM65535.1 - 4.5e-12 46.5 0.0 5.4e-09 36.5 0.0 2.4 2 0 0 2 2 2 2 SET domain zf-MYND PF01753.13 CAM65535.1 - 0.00011 21.9 10.4 0.00011 21.9 7.2 3.1 3 1 0 3 3 3 1 MYND finger G-patch PF01585.18 CAM65537.1 - 1.3e-11 44.0 2.1 2.2e-11 43.3 1.4 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CAM65537.1 - 9.7e-08 31.7 0.9 2.3e-07 30.5 0.6 1.7 1 0 0 1 1 1 1 DExH-box splicing factor binding site Kinesin PF00225.18 CAM65538.1 - 6.6e-63 212.4 0.0 1.3e-62 211.4 0.0 1.4 1 1 0 1 1 1 1 Kinesin motor domain AAA_16 PF13191.1 CAM65538.1 - 0.0085 16.0 1.2 0.023 14.6 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CAM65538.1 - 0.11 12.6 0.2 0.51 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 CAM65538.1 - 0.12 12.2 0.1 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 ATG16 PF08614.6 CAM65538.1 - 1.2 8.9 8.2 4.2 7.1 1.4 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF148 PF02520.12 CAM65539.1 - 4.2 7.1 11.3 5.1 6.9 0.1 3.9 4 0 0 4 4 4 0 Domain of unknown function DUF148 Thioredoxin PF00085.15 CAM65540.1 - 1.5e-28 98.4 0.0 1.8e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 CAM65540.1 - 4.6e-07 29.7 0.0 6.3e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CAM65540.1 - 1.4e-06 28.4 0.0 1.5e-05 25.1 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CAM65540.1 - 7.3e-05 22.8 0.0 0.0015 18.5 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_5 PF13743.1 CAM65540.1 - 0.0041 16.7 0.0 0.64 9.5 0.0 2.1 2 0 0 2 2 2 2 Thioredoxin Defensin_propep PF00879.13 CAM65540.1 - 0.056 13.3 1.5 0.097 12.6 1.0 1.3 1 0 0 1 1 1 0 Defensin propeptide Redoxin PF08534.5 CAM65540.1 - 0.079 12.4 0.0 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 Redoxin TraF PF13728.1 CAM65540.1 - 0.093 12.2 0.0 0.16 11.4 0.0 1.4 1 1 0 1 1 1 0 F plasmid transfer operon protein LPAM_1 PF08139.7 CAM65540.1 - 1.1 9.5 4.1 2.3 8.5 2.8 1.5 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site 2OG-FeII_Oxy_2 PF13532.1 CAM65541.2 - 9.2e-09 35.4 0.0 4.8e-08 33.0 0.0 1.8 1 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF2188 PF09954.4 CAM65541.2 - 0.072 13.0 0.9 0.24 11.3 0.6 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) DeoC PF01791.4 CAM65542.1 - 3e-43 147.8 8.7 3.5e-43 147.6 6.0 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase PilX_N PF14341.1 CAM65542.1 - 0.14 11.8 0.4 0.52 10.0 0.1 2.2 3 0 0 3 3 3 0 PilX N-terminal SNase PF00565.12 CAM65543.1 - 7.2e-18 64.8 0.0 1.1e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Ada_Zn_binding PF02805.11 CAM65543.1 - 0.032 13.7 0.7 0.064 12.8 0.1 1.8 2 0 0 2 2 2 0 Metal binding domain of Ada Med9 PF07544.8 CAM65544.1 - 0.01 15.5 18.4 0.17 11.6 2.8 4.4 3 2 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Sporozoite_P67 PF05642.6 CAM65544.1 - 0.18 9.6 5.2 0.064 11.1 0.7 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Myosin_tail_1 PF01576.14 CAM65544.1 - 0.61 7.7 51.3 0.0078 13.9 4.0 2.9 2 1 1 3 3 3 0 Myosin tail Reo_sigmaC PF04582.7 CAM65544.1 - 1.5 7.9 20.4 0.2 10.8 0.4 3.8 2 1 1 4 4 4 0 Reovirus sigma C capsid protein Tropomyosin_1 PF12718.2 CAM65544.1 - 4.4 7.1 55.9 0.14 11.9 3.9 4.1 4 0 0 4 4 4 0 Tropomyosin like TraC PF07820.7 CAM65545.2 - 0.57 10.4 0.0 0.57 10.4 0.0 2.3 3 0 0 3 3 3 0 TraC-like protein PIG-X PF08320.7 CAM65547.1 - 0.067 12.4 0.0 0.66 9.2 0.0 2.3 2 1 1 3 3 3 0 PIG-X / PBN1 WD40 PF00400.27 CAM65548.1 - 2.8e-07 30.1 5.9 3.3e-06 26.7 0.1 3.6 4 0 0 4 4 4 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CAM65548.1 - 0.13 10.9 0.1 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Nup133 N terminal like DUF4379 PF14311.1 CAM65550.2 - 4.2e-27 93.7 21.0 1.3e-10 40.9 0.1 4.7 4 0 0 4 4 4 3 Domain of unknown function (DUF4379) HypA PF01155.14 CAM65550.2 - 0.057 13.1 15.0 1.4 8.6 0.0 4.1 4 1 0 5 5 5 0 Hydrogenase expression/synthesis hypA family NTF2 PF02136.15 CAM65552.1 - 1.6e-15 57.4 0.0 1.9e-15 57.2 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Thioredoxin PF00085.15 CAM65554.1 - 6.4e-10 38.6 0.0 8e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CAM65554.1 - 0.062 13.4 0.0 0.12 12.5 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain DUF1637 PF07847.7 CAM65558.1 - 1.3e-49 168.2 0.0 1.8e-49 167.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) CDO_I PF05995.7 CAM65558.1 - 0.0054 15.9 0.0 0.93 8.6 0.0 2.3 3 0 0 3 3 3 2 Cysteine dioxygenase type I FAD_binding_3 PF01494.14 CAM65559.1 - 1.5e-09 37.4 0.2 1.3e-08 34.3 0.1 2.5 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 CAM65559.1 - 0.013 14.3 0.0 0.024 13.4 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase Hpt PF01627.18 CAM65559.1 - 0.035 14.1 0.7 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 Hpt domain EnY2 PF10163.4 CAM65560.1 - 4.2e-05 23.3 0.0 5.6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Transcription factor e(y)2 PS-DH PF14765.1 CAM65560.1 - 0.0094 15.1 1.5 0.0093 15.1 1.1 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase DUF399 PF04187.8 CAM65560.1 - 0.012 15.1 0.7 0.013 14.9 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF399 Phage_head_chap PF11113.3 CAM65560.1 - 0.017 14.9 0.1 0.65 9.9 0.1 2.2 2 0 0 2 2 2 0 Head assembly gene product DFF-C PF09033.5 CAM65561.1 - 0.8 9.5 3.2 1.3 8.8 2.2 1.3 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain FA_hydroxylase PF04116.8 CAM65561.1 - 5.7 7.3 5.8 1.9 8.9 0.1 2.4 1 1 1 2 2 2 0 Fatty acid hydroxylase superfamily Coprogen_oxidas PF01218.13 CAM65562.1 - 6.3e-141 468.1 0.1 7.1e-141 467.9 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Flavodoxin_5 PF12724.2 CAM65563.1 - 5.2e-46 156.1 0.1 6.5e-46 155.8 0.1 1.1 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_3 PF12641.2 CAM65563.1 - 0.0046 16.4 0.1 0.0083 15.5 0.0 1.4 1 1 0 1 1 1 1 Flavodoxin domain Cyt-b5 PF00173.23 CAM65564.1 - 4.4e-05 23.1 0.0 6.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CLN3 PF02487.12 CAM65565.2 - 1.1e-28 100.1 35.8 3.2e-14 52.5 7.4 3.3 2 1 1 3 3 3 3 CLN3 protein ThiF PF00899.16 CAM65566.1 - 1.6e-29 102.4 0.1 3.7e-29 101.2 0.0 1.6 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 CAM65566.1 - 1.4e-05 25.2 0.1 0.001 19.1 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 CAM65566.1 - 0.0015 18.4 5.6 0.53 10.1 0.1 2.6 2 0 0 2 2 2 2 short chain dehydrogenase 2-Hacid_dh_C PF02826.14 CAM65566.1 - 0.038 13.1 0.0 7.4 5.6 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain KR PF08659.5 CAM65566.1 - 0.29 10.7 3.8 3.9 7.0 0.1 2.8 2 1 0 2 2 2 0 KR domain Isy1 PF06246.7 CAM65567.1 - 2.2e-09 37.0 12.1 1.1e-06 28.2 8.4 2.2 1 1 0 1 1 1 1 Isy1-like splicing family DOT1 PF08123.8 CAM65568.1 - 5.4e-20 71.5 0.0 9.3e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 CAM65568.1 - 2.3e-07 31.3 0.0 3.8e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAM65568.1 - 6.1e-06 25.8 0.0 9.4e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CAM65568.1 - 2.7e-05 24.1 0.0 4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAM65568.1 - 9.5e-05 22.6 0.0 0.00015 22.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 CAM65568.1 - 0.0021 17.7 0.0 0.0036 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CAM65568.1 - 0.0033 17.8 0.0 0.007 16.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CAM65568.1 - 0.0091 15.1 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 CAM65568.1 - 0.025 15.0 0.0 0.04 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain AdoMet_MTase PF07757.8 CAM65568.1 - 0.062 13.4 0.0 0.096 12.8 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 CAM65568.1 - 0.073 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 CAM65568.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.12 CAM65568.1 - 0.14 11.2 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase M20_dimer PF07687.9 CAM65569.1 - 1.2e-05 25.0 0.0 2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Adaptin_N PF01602.15 CAM65571.1 - 1.7e-85 287.3 8.6 2.2e-85 286.9 6.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 CAM65571.1 - 0.0022 18.2 1.2 1.8 8.8 0.0 4.2 4 1 0 4 4 4 2 HEAT repeats EamA PF00892.15 CAM65572.1 - 8.5e-11 41.9 23.4 1.5e-08 34.7 0.5 3.2 3 1 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 CAM65572.1 - 3.6e-05 23.9 3.2 3.6e-05 23.9 2.2 3.9 2 1 0 3 3 3 1 Multidrug resistance efflux transporter DUF914 PF06027.7 CAM65572.1 - 0.0006 18.7 5.4 0.0006 18.7 3.7 1.6 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 CAM65572.1 - 0.00084 18.3 3.4 0.0015 17.5 2.4 1.3 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 CAM65572.1 - 0.019 14.5 0.0 0.019 14.5 0.0 3.0 3 1 0 3 3 3 0 Triose-phosphate Transporter family Rav1p_C PF12234.3 CAM65574.1 - 2.8e-31 108.4 0.7 1.6e-25 89.4 1.1 3.6 3 1 0 3 3 3 3 RAVE protein 1 C terminal zf-C3HC4 PF00097.20 CAM65575.1 - 1.2e-06 28.0 10.3 2.7e-06 26.9 7.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CAM65575.1 - 2.3e-06 27.2 11.3 2.3e-06 27.2 7.8 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 CAM65575.1 - 3.7e-06 26.8 10.6 3.7e-06 26.8 7.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CAM65575.1 - 2.1e-05 24.0 9.8 7e-05 22.4 6.8 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CAM65575.1 - 4.5e-05 23.2 9.3 0.00011 21.9 6.4 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-TRAF PF02176.13 CAM65575.1 - 0.00031 21.0 0.5 0.00097 19.4 0.4 1.9 1 0 0 1 1 1 1 TRAF-type zinc finger zf-RING_5 PF14634.1 CAM65575.1 - 0.00047 19.8 10.3 0.0012 18.5 7.1 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CAM65575.1 - 0.00086 18.9 8.6 0.0021 17.7 5.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger U-box PF04564.10 CAM65575.1 - 0.02 14.8 0.0 0.078 12.9 0.0 2.1 2 0 0 2 2 2 0 U-box domain zf-Nse PF11789.3 CAM65575.1 - 0.081 12.4 3.6 0.29 10.6 2.5 1.9 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF1244 PF06844.6 CAM65575.1 - 0.092 12.5 0.1 0.24 11.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) zf-rbx1 PF12678.2 CAM65575.1 - 0.62 10.2 13.4 0.042 13.9 5.3 2.1 2 1 0 2 2 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 CAM65575.1 - 9.4 6.1 11.9 2.9 7.7 4.3 3.0 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger UPF0506 PF11703.3 CAM65577.1 - 0.068 13.1 2.0 0.13 12.2 1.4 1.4 1 0 0 1 1 1 0 UPF0506 DEAD PF00270.24 CAM65578.1 - 1.9e-42 144.6 0.0 5.8e-42 143.0 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM65578.1 - 5.3e-21 74.2 0.0 4.6e-20 71.2 0.1 2.5 2 1 1 3 3 3 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 CAM65578.1 - 0.0032 17.4 0.0 0.0051 16.7 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.10 CAM65578.1 - 0.01 15.6 0.0 0.053 13.3 0.0 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Pkinase PF00069.20 CAM65579.1 - 3.5e-50 170.5 0.0 5.6e-50 169.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM65579.1 - 1.4e-32 112.7 0.0 2.4e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM65579.1 - 6.5e-08 31.8 0.0 1e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CAM65579.1 - 0.0085 15.8 0.0 0.0085 15.8 0.0 2.8 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.20 CAM65580.1 - 2.6e-50 171.0 0.0 2.1e-30 105.7 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAM65580.1 - 2.1e-34 118.8 0.0 2.5e-20 72.6 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CAM65580.1 - 0.0021 17.0 0.1 0.55 9.1 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 CAM65580.1 - 0.049 12.6 0.3 0.65 9.0 0.2 2.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family PTPA PF03095.10 CAM65582.1 - 4.7e-104 347.7 0.0 5.7e-104 347.4 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF3329 PF11808.3 CAM65582.1 - 0.045 13.8 0.0 0.15 12.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) PLDc_2 PF13091.1 CAM65583.1 - 2.6e-08 33.6 0.0 0.00046 19.9 0.0 3.5 3 1 0 3 3 3 2 PLD-like domain PLDc PF00614.17 CAM65583.1 - 2.4e-06 27.1 0.4 2.3e-05 24.0 0.1 2.6 3 0 0 3 3 3 1 Phospholipase D Active site motif Eno-Rase_NADH_b PF12242.3 CAM65583.1 - 0.027 14.2 0.2 0.08 12.7 0.2 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PetL PF05115.9 CAM65583.1 - 0.27 11.1 4.4 0.61 10.0 3.1 1.6 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit VI (PetL) CIAPIN1 PF05093.8 CAM65586.1 - 1.2e-16 60.6 16.3 1.7e-15 56.9 11.3 2.0 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Pkinase PF00069.20 CAM65588.2 - 1.1e-35 123.0 0.0 3.6e-14 52.5 0.0 3.4 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CAM65588.2 - 2.3e-15 56.3 0.0 2.1e-10 40.1 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CAM65588.2 - 0.00098 18.1 0.0 0.01 14.8 0.0 2.4 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.9 CAM65588.2 - 0.67 8.9 0.0 1.2 8.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 CAM65588.2 - 2.4 6.8 0.0 3.8 6.2 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Homoserine_dh PF00742.14 CAM65589.1 - 9.9e-68 227.3 0.0 1.4e-67 226.8 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 CAM65589.1 - 5.8e-11 42.8 0.1 1.3e-10 41.7 0.1 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Tn7_Tnp_TnsA_C PF08721.6 CAM65589.1 - 0.065 13.2 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 TnsA endonuclease C terminal Peptidase_M20 PF01546.23 CAM65590.1 - 1e-32 113.1 0.0 1.4e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CAM65590.1 - 3.5e-18 65.3 0.0 5.7e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain HECT PF00632.20 CAM65591.2 - 2.4e-89 299.6 0.0 3.4e-89 299.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ZZ PF00569.12 CAM65591.2 - 0.36 10.4 8.9 0.79 9.3 6.2 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type FadA PF09403.5 CAM65591.2 - 0.8 9.7 6.6 2.6 8.0 4.5 1.9 1 0 0 1 1 1 0 Adhesion protein FadA C1_3 PF07649.7 CAM65591.2 - 1.4 9.0 15.3 2.6 8.1 10.6 1.5 1 0 0 1 1 1 0 C1-like domain DUF4557 PF15101.1 CAM65591.2 - 2.2 8.0 3.4 7.1 6.4 2.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF972 PF06156.8 CAM65591.2 - 4.7 7.5 4.8 20 5.5 3.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Peptidase_S49_N PF08496.5 CAM65591.2 - 9.4 6.0 3.3 32 4.2 2.3 1.8 1 0 0 1 1 1 0 Peptidase family S49 N-terminal UPF0172 PF03665.8 CAM65592.1 - 1.2e-74 250.1 0.0 1.3e-74 249.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) LRR_4 PF12799.2 CAM65593.1 - 7.9e-07 28.5 0.1 0.00013 21.5 0.2 2.4 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM65593.1 - 0.0027 17.4 0.2 0.0053 16.4 0.1 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 CAM65593.1 - 0.056 13.5 1.4 1.1 9.5 0.7 2.9 2 1 0 2 2 2 0 Leucine Rich Repeat Flagellar_rod PF05149.7 CAM65594.1 - 1.2e-09 37.7 18.2 1.2e-09 37.7 12.6 2.6 3 0 0 3 3 3 1 Paraflagellar rod protein DUF3275 PF11679.3 CAM65594.1 - 0.11 12.0 14.1 0.59 9.7 0.1 3.6 2 1 0 3 3 3 0 Protein of unknown function (DUF3275) Sec20 PF03908.8 CAM65594.1 - 0.87 9.3 3.0 13 5.5 0.1 2.9 3 0 0 3 3 3 0 Sec20 ABA_GPCR PF12430.3 CAM65596.1 - 3.6e-40 137.1 0.1 8.1e-40 136.0 0.1 1.6 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 CAM65596.1 - 3.6e-11 42.9 0.0 1.3e-10 41.1 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3735) NUDIX PF00293.23 CAM65597.1 - 4.6e-11 42.5 0.1 1.7e-10 40.6 0.0 1.9 2 0 0 2 2 2 1 NUDIX domain DUF747 PF05346.6 CAM65598.1 - 1.2e-57 195.4 0.5 1.7e-57 194.9 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family DUF1751 PF08551.5 CAM65599.1 - 0.0002 21.5 0.5 0.00055 20.2 0.2 1.8 1 1 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Med3 PF11593.3 CAM65599.1 - 1.6 7.9 5.9 2.4 7.3 4.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal tRNA_Me_trans PF03054.11 CAM65601.2 - 1.5e-40 138.8 0.0 1.5e-26 92.7 0.0 4.5 4 0 0 4 4 4 4 tRNA methyl transferase Asn_synthase PF00733.16 CAM65601.2 - 0.013 14.9 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase NAD_synthase PF02540.12 CAM65601.2 - 0.017 14.0 0.1 0.033 13.0 0.1 1.4 1 0 0 1 1 1 0 NAD synthase Sec7 PF01369.15 CAM65602.1 - 1.4e-36 125.9 0.0 3.3e-36 124.7 0.0 1.6 1 0 0 1 1 1 1 Sec7 domain EF-hand_8 PF13833.1 CAM65603.1 - 2.9e-23 81.2 0.4 1.9e-06 27.3 0.0 4.6 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 CAM65603.1 - 6e-23 78.3 9.0 4.4e-07 28.7 0.0 5.2 6 0 0 6 6 6 4 EF hand EF-hand_6 PF13405.1 CAM65603.1 - 1.3e-22 77.6 0.6 0.00011 21.8 0.0 5.5 6 0 0 6 6 6 4 EF-hand domain EF-hand_7 PF13499.1 CAM65603.1 - 6.1e-21 74.3 0.0 2.8e-05 24.1 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 CAM65603.1 - 3.2e-15 54.6 4.3 7e-06 25.1 0.0 4.8 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.2 CAM65603.1 - 0.00052 19.7 0.0 1.6 8.5 0.0 3.2 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand TFIID-18kDa PF02269.11 CAM65603.1 - 0.018 14.8 0.0 2.9 7.7 0.0 3.4 4 0 0 4 4 4 0 Transcription initiation factor IID, 18kD subunit SPARC_Ca_bdg PF10591.4 CAM65603.1 - 0.027 14.5 0.0 1 9.3 0.0 2.7 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 CAM65603.1 - 0.065 13.1 0.9 9.1 6.2 0.1 3.4 3 1 0 3 3 3 0 EF-hand domain Peptidase_M16_C PF05193.16 CAM65604.2 - 2.4e-25 89.2 0.0 3.4e-14 52.9 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain M16C_assoc PF08367.6 CAM65604.2 - 9.4e-23 80.3 0.0 1.5e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16 PF00675.15 CAM65604.2 - 2.7e-16 59.6 2.0 3.1e-12 46.4 0.0 3.0 3 0 0 3 3 3 2 Insulinase (Peptidase family M16) Shugoshin_C PF07557.6 CAM65604.2 - 0.036 13.5 0.3 0.13 11.8 0.2 2.0 1 0 0 1 1 1 0 Shugoshin C terminus DUF1542 PF07564.6 CAM65604.2 - 1 9.4 4.3 0.75 9.8 0.6 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) S-methyl_trans PF02574.11 CAM65605.1 - 1.3e-93 313.6 0.0 2.2e-93 312.8 0.0 1.4 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Met_synt_B12 PF02965.12 CAM65605.1 - 6.1e-66 221.6 0.1 2.1e-65 219.8 0.0 1.9 2 0 0 2 2 2 1 Vitamin B12 dependent methionine synthase, activation domain Pterin_bind PF00809.17 CAM65605.1 - 2.8e-36 124.8 0.0 8.8e-36 123.2 0.0 1.9 1 0 0 1 1 1 1 Pterin binding enzyme B12-binding_2 PF02607.12 CAM65605.1 - 1e-21 76.7 0.1 7.6e-21 73.9 0.0 2.6 2 0 0 2 2 2 1 B12 binding domain B12-binding PF02310.14 CAM65605.1 - 1.9e-21 76.1 0.4 1.2e-20 73.5 0.2 2.5 3 0 0 3 3 3 1 B12 binding domain Rad9_Rad53_bind PF08605.5 CAM65606.1 - 0.13 12.0 0.0 0.71 9.6 0.0 2.2 2 0 0 2 2 2 0 Fungal Rad9-like Rad53-binding Cytochrom_C1 PF02167.10 CAM65608.1 - 5e-66 222.4 0.0 6.1e-66 222.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family MaoC_dehydratas PF01575.14 CAM65611.1 - 5.1e-24 83.9 0.0 7.5e-24 83.4 0.0 1.3 1 1 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 CAM65611.1 - 3.3e-09 36.6 0.0 4.8e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase 4HBT PF03061.17 CAM65611.1 - 0.022 14.8 0.0 0.057 13.5 0.0 1.7 2 0 0 2 2 2 0 Thioesterase superfamily MaoC_dehydratas PF01575.14 CAM65612.1 - 1.4e-24 85.8 0.0 2.3e-24 85.1 0.0 1.3 1 1 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 CAM65612.1 - 3.9e-12 46.1 0.0 1.1e-11 44.6 0.0 1.7 1 1 1 2 2 2 1 N-terminal half of MaoC dehydratase 4HBT PF03061.17 CAM65612.1 - 0.00025 21.1 0.0 0.00044 20.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily NOT2_3_5 PF04153.13 CAM65613.1 - 0.029 14.2 0.6 0.032 14.1 0.4 1.2 1 0 0 1 1 1 0 NOT2 / NOT3 / NOT5 family Acyl-CoA_dh_N PF02771.11 CAM65614.1 - 9.7e-11 42.2 0.0 2.6e-10 40.8 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CAM65614.1 - 0.00019 20.8 0.2 0.00046 19.6 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CAM65614.1 - 0.018 15.2 3.3 0.46 10.7 1.1 2.3 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain MobB PF03205.9 CAM65617.2 - 1.1e-08 34.8 0.0 4.4e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Clp1 PF06807.9 CAM65617.2 - 0.039 13.7 0.0 0.2 11.4 0.0 2.1 2 0 0 2 2 2 0 Pre-mRNA cleavage complex II protein Clp1 AAA_22 PF13401.1 CAM65617.2 - 0.16 12.0 0.0 0.66 10.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CAM65617.2 - 0.28 11.3 0.0 0.55 10.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Ras PF00071.17 CAM65619.1 - 8.1e-55 184.6 0.0 9.6e-55 184.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAM65619.1 - 7.6e-15 55.4 0.0 1.2e-14 54.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAM65619.1 - 8.3e-11 41.4 0.0 1e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CAM65619.1 - 0.00011 21.6 0.0 0.0017 17.8 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CAM65619.1 - 0.0013 18.6 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CAM65619.1 - 0.0015 17.7 0.0 0.0018 17.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Mito_carr PF00153.22 CAM65622.1 - 3e-34 116.5 5.1 1.5e-13 50.2 0.3 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein CP_ATPgrasp_1 PF04174.8 CAM65622.1 - 0.058 12.0 0.0 0.09 11.3 0.0 1.3 1 0 0 1 1 1 0 A circularly permuted ATPgrasp TMEM141 PF15110.1 CAM65622.1 - 0.07 13.4 0.5 0.83 9.9 0.1 2.7 2 0 0 2 2 2 0 TMEM141 protein family Period_C PF12114.3 CAM65622.1 - 3.8 7.0 6.1 5.5 6.5 4.2 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Sec20 PF03908.8 CAM65623.1 - 0.00018 21.1 0.9 0.00051 19.6 0.5 1.9 1 1 1 2 2 2 1 Sec20 V-SNARE_C PF12352.3 CAM65623.1 - 0.042 13.9 1.4 0.1 12.6 0.9 1.6 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus Cytochrom_B562 PF07361.6 CAM65623.1 - 0.092 13.1 0.5 0.092 13.1 0.4 2.1 2 1 0 2 2 2 0 Cytochrome b562 CcmD PF04995.9 CAM65623.1 - 0.1 12.3 0.3 0.1 12.3 0.2 3.1 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) DUF4407 PF14362.1 CAM65623.1 - 2.8 6.7 11.3 4.9 6.0 7.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_L7Ae PF01248.21 CAM65624.1 - 8.3e-20 70.1 0.3 1.7e-19 69.1 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CAM65624.1 - 0.00022 21.0 0.1 0.00034 20.4 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 Ribosomal_L7Ae PF01248.21 CAM65625.1 - 9.7e-20 69.8 0.3 1.8e-19 69.0 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CAM65625.1 - 0.00024 20.9 0.1 0.00037 20.3 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 Gly-zipper_OmpA PF13436.1 CAM65626.1 - 0.11 12.1 9.9 0.22 11.2 6.8 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain CDC45 PF02724.9 CAM65626.1 - 1.4 6.8 3.9 1.5 6.7 2.3 1.3 1 1 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.1 CAM65626.1 - 4.1 7.7 14.2 0.18 12.1 4.5 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 CAM65626.1 - 6.1 6.3 9.4 11 5.5 6.5 1.3 1 0 0 1 1 1 0 Nucleoplasmin DHC_N2 PF08393.8 CAM65627.2 - 1.9e-33 115.5 0.0 4.4e-33 114.3 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA PF00004.24 CAM65627.2 - 0.015 15.4 0.0 0.046 13.9 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cation_ATPase_C PF00689.16 CAM65629.1 - 4.5e-36 124.0 3.6 8.8e-36 123.1 2.5 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.15 CAM65629.1 - 1.6e-32 112.4 0.0 5.4e-32 110.6 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CAM65629.1 - 1.2e-23 84.6 0.0 1.1e-22 81.4 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CAM65629.1 - 2.7e-11 43.9 0.0 9.6e-11 42.1 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CAM65629.1 - 4.9e-11 42.4 0.0 1.1e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CAM65629.1 - 3.6e-06 26.7 0.0 0.0003 20.4 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Sel1 PF08238.7 CAM65630.1 - 5e-22 77.8 38.6 7.1e-09 36.0 0.1 8.8 9 0 0 9 9 9 7 Sel1 repeat ETF_QO PF05187.8 CAM65631.1 - 2.7e-40 136.7 0.0 4.4e-40 136.0 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 CAM65631.1 - 1.1e-09 37.6 1.1 0.00021 20.2 0.4 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CAM65631.1 - 4.3e-08 32.4 2.7 0.0014 17.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 CAM65631.1 - 7.7e-07 29.0 0.2 2.8e-06 27.2 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CAM65631.1 - 3.7e-05 22.9 0.1 0.018 14.1 0.2 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_9 PF13454.1 CAM65631.1 - 0.00017 21.4 0.2 0.00032 20.5 0.1 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CAM65631.1 - 0.00033 20.5 0.0 0.00076 19.4 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CAM65631.1 - 0.0011 19.2 0.2 0.45 10.9 0.2 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CAM65631.1 - 0.0045 15.4 0.3 0.0069 14.9 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.9 CAM65631.1 - 0.0088 14.7 0.5 0.074 11.6 0.1 2.0 2 0 0 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.7 CAM65631.1 - 0.0092 14.9 0.1 0.015 14.2 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.2 CAM65631.1 - 0.023 13.8 0.3 0.036 13.1 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CAM65631.1 - 0.025 13.6 0.8 0.038 13.0 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.1 CAM65631.1 - 0.029 14.4 0.1 0.054 13.5 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.2 CAM65631.1 - 0.065 13.6 1.0 0.2 12.0 0.7 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_10 PF13237.1 CAM65631.1 - 0.067 13.0 0.5 0.21 11.3 0.3 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain GldM_N PF12081.3 CAM65634.1 - 0.0015 18.1 2.9 1.5 8.3 0.0 3.7 2 2 1 3 3 3 2 GldM N-terminal domain Cast PF10174.4 CAM65634.1 - 0.013 13.5 39.4 0.024 12.7 8.4 3.5 2 1 1 3 3 3 0 RIM-binding protein of the cytomatrix active zone Ycf54 PF10674.4 CAM65634.1 - 0.045 13.8 0.2 0.23 11.5 0.1 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2488) RBD-FIP PF09457.5 CAM65634.1 - 0.11 12.2 11.8 0.49 10.2 0.0 3.8 3 0 0 3 3 3 0 FIP domain DUF4449 PF14613.1 CAM65634.1 - 0.85 9.5 9.1 4.3 7.2 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4449) TBPIP PF07106.8 CAM65634.1 - 1.7 8.2 26.4 1.7 8.1 2.5 5.2 4 1 2 6 6 6 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) V-SNARE_C PF12352.3 CAM65638.1 - 1e-08 35.1 5.1 1.6e-08 34.4 3.6 1.3 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus ATG16 PF08614.6 CAM65638.1 - 0.00075 19.3 0.9 0.00094 19.0 0.6 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Synaptobrevin PF00957.16 CAM65638.1 - 0.034 13.7 2.3 0.11 12.0 1.6 1.8 1 1 0 1 1 1 0 Synaptobrevin DUF720 PF05302.6 CAM65638.1 - 1.2 8.9 6.7 0.17 11.6 1.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF720) Ribosomal_S4 PF00163.14 CAM65639.1 - 7.7e-29 99.9 0.4 1.5e-28 98.9 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CAM65639.1 - 6.2e-14 51.1 0.4 1.3e-13 50.1 0.3 1.6 1 0 0 1 1 1 1 S4 domain Pkinase PF00069.20 CAM65640.1 - 1.3e-42 145.7 0.0 1.1e-26 93.5 0.0 3.7 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CAM65640.1 - 2.7e-22 79.0 0.0 7.2e-16 58.0 0.0 3.0 3 1 0 3 3 3 2 Protein tyrosine kinase PAP_assoc PF03828.14 CAM65641.1 - 0.0031 17.4 0.0 0.0083 16.0 0.0 1.8 1 1 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 CAM65641.1 - 0.0034 17.6 0.1 0.007 16.6 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain EF-hand_1 PF00036.27 CAM65642.1 - 4.4e-27 91.2 8.3 4.9e-09 34.8 0.5 4.4 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.1 CAM65642.1 - 2.9e-23 81.7 2.5 3e-12 46.4 0.6 2.9 2 1 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 CAM65642.1 - 2.9e-22 76.5 3.6 5.1e-09 35.2 0.1 4.7 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.1 CAM65642.1 - 6.3e-19 67.3 9.8 1.7e-13 49.9 0.7 4.0 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 CAM65642.1 - 4.6e-17 60.5 10.2 4.5e-06 25.7 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 CAM65642.1 - 8.2e-10 38.4 0.1 5.3e-05 23.0 0.0 2.7 2 1 0 3 3 3 2 EF-hand domain EF-hand_4 PF12763.2 CAM65642.1 - 1.5e-06 27.8 0.9 0.0087 15.7 0.0 2.7 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand HEAT_2 PF13646.1 CAM65644.1 - 8.1e-13 48.4 23.8 5.7e-05 23.3 0.1 8.4 6 3 1 7 7 7 5 HEAT repeats HEAT PF02985.17 CAM65644.1 - 3.3e-11 42.2 17.9 0.0028 17.6 0.2 9.8 10 0 0 10 10 10 3 HEAT repeat HEAT_EZ PF13513.1 CAM65644.1 - 6.2e-08 32.9 34.2 0.00043 20.6 1.2 11.5 8 1 2 10 10 10 3 HEAT-like repeat CLASP_N PF12348.3 CAM65644.1 - 0.00063 19.1 0.5 4.5 6.5 0.0 3.8 3 1 1 4 4 4 3 CLASP N terminal IBN_N PF03810.14 CAM65644.1 - 0.0037 17.1 0.0 0.046 13.6 0.0 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain Adaptin_N PF01602.15 CAM65644.1 - 0.015 13.6 0.1 4.2 5.5 0.0 3.1 3 0 0 3 3 3 0 Adaptin N terminal region MMS19_C PF12460.3 CAM65644.1 - 0.21 10.2 0.0 1.5 7.4 0.0 2.5 2 0 0 2 2 2 0 RNAPII transcription regulator C-terminal DUF3437 PF11919.3 CAM65644.1 - 1.6 8.4 5.3 0.64 9.7 0.2 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF3437) MCD PF05292.6 CAM65645.1 - 1.3e-55 188.5 0.0 4.2e-33 114.5 0.0 3.1 1 1 1 2 2 2 2 Malonyl-CoA decarboxylase (MCD) Cytochrom_D1 PF02239.11 CAM65646.1 - 1.9 6.7 0.0 3.3 5.9 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain PPI_Ypi1 PF07491.6 CAM65647.1 - 3.2e-18 65.0 2.7 6.7e-18 64.0 1.9 1.6 1 1 0 1 1 1 1 Protein phosphatase inhibitor SR-25 PF10500.4 CAM65647.1 - 0.074 12.5 2.5 0.099 12.0 1.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Orbi_VP6 PF01516.11 CAM65647.1 - 9.7 5.1 6.6 14 4.6 4.6 1.2 1 0 0 1 1 1 0 Orbivirus helicase VP6 His_Phos_1 PF00300.17 CAM65650.2 - 9.1e-29 100.5 0.1 2.3e-28 99.2 0.1 1.8 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) 6PF2K PF01591.13 CAM65650.2 - 7.3e-18 64.4 0.1 2.1e-10 40.0 0.0 3.4 3 0 0 3 3 3 3 6-phosphofructo-2-kinase AAA_33 PF13671.1 CAM65650.2 - 0.00081 19.2 0.2 0.12 12.2 0.0 3.3 4 0 0 4 4 4 1 AAA domain AAA_17 PF13207.1 CAM65650.2 - 0.097 13.4 0.0 0.33 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF739 PF05339.6 CAM65650.2 - 0.25 11.1 0.0 0.47 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF739) DnaJ PF00226.26 CAM65651.1 - 1.8e-08 34.0 0.1 1.2e-07 31.2 0.0 2.2 2 1 0 2 2 2 1 DnaJ domain DnaJ PF00226.26 CAM65652.1 - 6.7e-10 38.5 0.1 1.6e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 CAM65652.1 - 2.3e-05 24.2 0.0 6.1e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Pam16 FAD_binding_2 PF00890.19 CAM65654.1 - 9.4e-61 205.8 2.8 1.2e-60 205.5 1.9 1.2 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 CAM65654.1 - 2e-20 72.3 0.0 9.2e-20 70.2 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain RRM_6 PF14259.1 CAM65655.1 - 3.2e-05 23.8 0.0 5.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAM65655.1 - 0.00022 20.8 0.0 0.00035 20.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PGM_PMM_I PF02878.11 CAM65656.1 - 7.9e-13 48.0 0.0 3.6e-09 36.2 0.0 2.5 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.15 CAM65656.1 - 4.9e-10 39.2 0.1 1.1e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.11 CAM65656.1 - 1.9e-07 31.3 0.0 8.2e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 CAM65656.1 - 0.019 14.9 0.1 0.038 14.0 0.1 1.5 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Cyt-b5 PF00173.23 CAM65657.1 - 1.8e-05 24.4 0.0 2.1e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PD40 PF07676.7 CAM65657.1 - 0.13 11.9 1.3 1.8 8.3 0.2 2.2 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat UQ_con PF00179.21 CAM65659.1 - 2.5e-38 130.6 0.0 3.4e-38 130.2 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CAM65659.1 - 0.058 13.1 0.0 0.079 12.7 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B RRM_5 PF13893.1 CAM65661.1 - 9.4e-06 25.3 0.0 0.00065 19.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 CAM65662.1 - 7.1e-77 258.0 0.0 8.2e-77 257.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM65662.1 - 1.6e-39 135.5 0.0 1.9e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM65662.1 - 5.7e-10 38.6 0.0 1.5e-08 33.9 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 CAM65662.1 - 0.0014 17.7 0.1 0.0025 16.9 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CAM65662.1 - 0.002 17.4 0.1 0.0034 16.7 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CAM65662.1 - 0.0021 17.8 0.1 0.2 11.3 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family PKD_channel PF08016.7 CAM65663.1 - 0.023 13.1 12.3 0.036 12.5 8.6 1.2 1 0 0 1 1 1 0 Polycystin cation channel DUF3608 PF12257.3 CAM65664.1 - 2.4e-16 59.4 0.9 6.1e-11 41.7 0.0 3.2 3 0 0 3 3 3 3 Protein of unknown function (DUF3608) Radial_spoke PF04712.7 CAM65665.1 - 2.1e-06 26.8 9.9 2.5e-05 23.2 0.0 2.8 2 1 0 2 2 2 1 Radial spokehead-like protein CENP-B_dimeris PF09026.5 CAM65665.1 - 9e-05 22.6 8.1 0.00015 21.9 5.6 1.3 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Myc_N PF01056.13 CAM65665.1 - 0.0015 17.7 1.8 0.002 17.3 1.3 1.1 1 0 0 1 1 1 1 Myc amino-terminal region BNR PF02012.15 CAM65665.1 - 0.015 15.0 0.6 0.034 13.9 0.4 1.6 1 0 0 1 1 1 0 BNR/Asp-box repeat PBP1_TM PF14812.1 CAM65665.1 - 0.089 13.1 5.0 0.15 12.3 3.4 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Spore_coat_CotO PF14153.1 CAM65665.1 - 0.15 11.4 1.5 0.22 10.9 1.0 1.2 1 0 0 1 1 1 0 Spore coat protein CotO eIF-3c_N PF05470.7 CAM65665.1 - 0.16 10.0 0.8 0.2 9.7 0.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Sigma70_ner PF04546.8 CAM65665.1 - 0.17 11.5 10.6 0.24 10.9 7.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Ribosomal_60s PF00428.14 CAM65665.1 - 0.23 11.8 17.6 0.4 11.0 12.2 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Nucleoplasmin PF03066.10 CAM65665.1 - 0.44 10.0 10.6 0.68 9.4 7.4 1.2 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 CAM65665.1 - 0.58 8.0 10.1 0.81 7.5 7.0 1.1 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.11 CAM65665.1 - 0.94 8.4 6.1 1.3 7.9 4.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.9 CAM65665.1 - 1 7.3 5.2 1.3 6.9 3.6 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 CAM65665.1 - 1.3 8.2 6.3 1.9 7.6 4.4 1.2 1 0 0 1 1 1 0 NOA36 protein Med17 PF10156.4 CAM65665.1 - 1.6 6.9 3.9 2.1 6.5 2.7 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex RXT2_N PF08595.6 CAM65665.1 - 1.7 8.4 5.1 2.8 7.7 3.5 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.1 CAM65665.1 - 2.4 7.8 4.7 4.1 7.0 3.2 1.3 1 0 0 1 1 1 0 FAM176 family Daxx PF03344.10 CAM65665.1 - 5.2 5.4 12.4 6.9 5.0 8.6 1.1 1 0 0 1 1 1 0 Daxx Family Cwf_Cwc_15 PF04889.7 CAM65665.1 - 7.2 6.2 11.0 10 5.7 7.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF3437 PF11919.3 CAM65666.2 - 1.6e-22 79.0 0.4 2.2e-21 75.3 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) DUF2096 PF09869.4 CAM65667.2 - 1.8 8.3 0.1 3.5 7.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) NPV_P10 PF05531.7 CAM65668.1 - 0.0082 16.3 15.4 0.081 13.1 0.7 4.7 3 2 1 4 4 4 2 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.1 CAM65668.1 - 0.0098 14.4 53.5 0.17 10.2 15.1 2.1 1 1 1 2 2 2 2 AAA domain Reo_sigmaC PF04582.7 CAM65668.1 - 0.29 10.2 15.8 4.8 6.2 1.0 3.9 1 1 0 3 3 3 0 Reovirus sigma C capsid protein WEMBL PF05701.6 CAM65668.1 - 0.59 8.5 83.1 0.016 13.7 24.9 3.1 1 1 1 3 3 3 0 Weak chloroplast movement under blue light Filament PF00038.16 CAM65668.1 - 0.99 8.8 83.4 3.9 6.8 30.5 3.0 1 1 1 2 2 2 0 Intermediate filament protein EzrA PF06160.7 CAM65668.1 - 1.5 6.8 56.8 0.0073 14.5 11.8 3.1 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA DUF221 PF02714.10 CAM65669.1 - 0.15 10.9 0.1 0.22 10.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF221 PBP1_TM PF14812.1 CAM65669.1 - 0.59 10.4 4.0 6.4 7.1 1.0 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 CAM65669.1 - 2.4 8.4 9.1 2.6 8.3 0.8 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF4611 PF15387.1 CAM65669.1 - 9.5 6.4 9.6 15 5.7 1.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 CAM65670.1 - 1.8e-05 24.3 0.1 2e-05 24.1 0.1 1.1 1 0 0 1 1 1 1 Nucleoplasmin Nucleoplasmin PF03066.10 CAM65671.2 - 4.4e-06 26.2 0.4 4.4e-06 26.2 0.3 3.8 1 1 2 3 3 3 1 Nucleoplasmin CENP-T PF15511.1 CAM65671.2 - 3.2 6.8 26.1 4 6.5 18.1 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF3876 PF12992.2 CAM65672.1 - 0.087 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3876) DUF59 PF01883.14 CAM65673.1 - 1.1e-08 34.9 0.0 3e-08 33.5 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF59 PIF1 PF05970.9 CAM65674.2 - 1.1e-44 152.9 0.0 5.6e-36 124.2 0.0 2.8 3 0 0 3 3 3 2 PIF1-like helicase Herpes_Helicase PF02689.9 CAM65674.2 - 8.3e-12 43.7 1.0 1.5e-06 26.3 0.0 2.1 2 0 0 2 2 2 2 Helicase AAA_30 PF13604.1 CAM65674.2 - 4.1e-11 42.8 0.0 8.9e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CAM65674.2 - 7.8e-07 28.7 0.3 3.6e-06 26.6 0.2 2.2 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 CAM65674.2 - 9.4e-07 29.0 0.0 2.1e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 CAM65674.2 - 1.2e-05 25.0 0.1 0.00032 20.2 0.0 3.1 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 CAM65674.2 - 0.00015 20.7 0.0 0.00035 19.5 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_5 PF07728.9 CAM65674.2 - 0.00021 20.9 0.0 0.00064 19.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 CAM65674.2 - 0.00063 19.3 0.2 0.52 9.8 0.0 3.2 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 CAM65674.2 - 0.0036 17.3 0.2 0.01 15.8 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain UvrD_C_2 PF13538.1 CAM65674.2 - 0.0074 16.4 0.0 0.029 14.5 0.0 2.0 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AFG1_ATPase PF03969.11 CAM65674.2 - 0.014 14.2 0.0 0.025 13.3 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase NACHT PF05729.7 CAM65674.2 - 0.016 14.8 0.1 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 CAM65674.2 - 0.018 14.9 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 CAM65674.2 - 0.02 14.6 0.2 0.63 9.7 0.3 2.5 2 0 0 2 2 2 0 NTPase PhoH PF02562.11 CAM65674.2 - 0.063 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.22 CAM65674.2 - 0.11 12.7 0.1 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.12 CAM65674.2 - 0.11 11.8 0.0 0.67 9.3 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF2075 PF09848.4 CAM65674.2 - 0.16 10.8 0.2 0.28 10.1 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.21 CAM65674.2 - 0.2 11.1 0.0 0.42 10.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Bac_DnaA PF00308.13 CAM65674.2 - 0.21 11.1 0.0 0.43 10.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein Rotamase PF00639.16 CAM65675.1 - 6.8e-23 81.2 0.0 7.7e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 CAM65675.1 - 1.4e-15 57.5 0.0 1.6e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 CAM65675.1 - 0.0056 17.3 0.0 0.0072 16.9 0.0 1.2 1 1 0 1 1 1 1 PPIC-type PPIASE domain Exonuc_VII_S PF02609.11 CAM65675.1 - 0.021 14.5 0.1 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 Exonuclease VII small subunit Sel1 PF08238.7 CAM65677.1 - 1.9e-07 31.5 7.0 0.0051 17.4 3.2 3.8 3 2 0 3 3 3 2 Sel1 repeat Macin PF14865.1 CAM65677.1 - 0.75 9.9 3.4 1.6 8.9 0.5 2.7 2 0 0 2 2 2 0 Macin E1-E2_ATPase PF00122.15 CAM65678.1 - 1.3e-23 83.2 0.0 6.3e-23 81.0 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 CAM65678.1 - 6e-22 78.7 0.0 1.2e-21 77.7 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CAM65678.1 - 3.2e-18 66.9 0.0 2.8e-17 63.8 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CAM65678.1 - 0.00012 22.0 0.0 0.00029 20.7 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CAM65678.1 - 0.015 14.8 0.3 0.049 13.2 0.1 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Tudor-knot PF11717.3 CAM65678.1 - 0.049 13.3 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Dpy-30 PF05186.8 CAM65679.1 - 8.6e-12 44.3 0.0 1.3e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Dpy-30 motif zf-C2H2 PF00096.21 CAM65681.1 - 3.5e-07 30.1 7.4 0.0012 19.0 0.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CAM65681.1 - 6e-05 23.1 8.3 0.1 12.9 1.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CAM65681.1 - 0.00025 20.8 2.7 0.23 11.4 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 CAM65681.1 - 0.0021 18.1 1.4 0.56 10.3 0.2 2.4 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding DUF629 PF04780.7 CAM65681.1 - 0.0023 16.5 0.7 0.23 9.9 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.2 CAM65681.1 - 0.0039 17.2 3.6 0.37 10.9 0.3 2.3 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met2 PF12907.2 CAM65681.1 - 0.008 16.1 1.9 0.008 16.1 1.3 2.4 2 0 0 2 2 2 1 Zinc-binding TFIIS_C PF01096.13 CAM65681.1 - 0.013 15.0 3.2 0.51 10.0 0.3 2.6 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-H2C2_2 PF13465.1 CAM65681.1 - 0.015 15.5 3.5 2.6 8.4 0.2 2.7 2 0 0 2 2 2 0 Zinc-finger double domain CpXC PF14353.1 CAM65681.1 - 0.019 14.9 0.4 6.2 6.8 0.1 2.3 2 0 0 2 2 2 0 CpXC protein zf-met PF12874.2 CAM65681.1 - 0.03 14.5 1.1 0.03 14.5 0.8 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF3505 PF12013.3 CAM65681.1 - 0.044 14.0 0.6 0.41 10.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3505) A2L_zn_ribbon PF08792.5 CAM65681.1 - 0.059 12.8 2.2 0.13 11.7 0.1 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-trcl PF13451.1 CAM65681.1 - 0.06 12.9 0.9 2.3 7.9 0.0 2.3 2 0 0 2 2 2 0 Probable zinc-binding domain C1_4 PF07975.7 CAM65681.1 - 0.096 12.7 1.1 3.9 7.5 0.0 2.4 2 0 0 2 2 2 0 TFIIH C1-like domain zf-C2H2_jaz PF12171.3 CAM65681.1 - 0.18 11.9 4.4 0.38 10.9 0.6 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_5 PF13719.1 CAM65681.1 - 0.31 10.6 4.5 7.4 6.2 0.0 2.8 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CAM65681.1 - 0.86 9.3 5.0 14 5.4 0.1 2.8 3 0 0 3 3 3 0 zinc-ribbon domain DUF1601 PF07671.6 CAM65682.1 - 0.0049 16.4 0.1 0.025 14.1 0.1 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1601) CENP-F_leu_zip PF10473.4 CAM65682.1 - 0.0095 15.8 10.5 0.0095 15.8 7.3 2.9 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WEMBL PF05701.6 CAM65682.1 - 0.031 12.7 33.3 0.021 13.3 13.6 2.1 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Macoilin PF09726.4 CAM65682.1 - 0.16 10.2 22.3 0.25 9.5 15.4 1.4 1 0 0 1 1 1 0 Transmembrane protein Reo_sigmaC PF04582.7 CAM65682.1 - 0.24 10.5 8.5 3.9 6.5 1.5 3.1 2 1 1 3 3 3 0 Reovirus sigma C capsid protein DUF489 PF04356.7 CAM65682.1 - 1.1 8.8 7.8 1.1 8.8 0.5 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF489) APG6 PF04111.7 CAM65682.1 - 2.2 7.2 23.9 1.3 8.0 3.5 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 Filament PF00038.16 CAM65682.1 - 6.9 6.0 28.8 18 4.6 20.0 1.9 1 1 0 1 1 1 0 Intermediate filament protein ERM PF00769.14 CAM65682.1 - 8 5.9 34.3 67 2.8 23.6 2.1 1 1 0 1 1 1 0 Ezrin/radixin/moesin family FA_desaturase PF00487.19 CAM65683.1 - 1.2e-44 152.7 21.6 1.6e-44 152.3 15.0 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 CAM65683.1 - 0.0072 16.1 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SIP PF04954.8 CAM65684.1 - 0.037 14.4 2.6 0.42 11.0 0.6 2.5 1 1 1 2 2 2 0 Siderophore-interacting protein TrbM PF07424.6 CAM65684.1 - 0.077 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 TrbM TORC_N PF12884.2 CAM65684.1 - 0.082 13.4 0.2 0.53 10.8 0.0 2.4 2 0 0 2 2 2 0 Transducer of regulated CREB activity, N terminus DUF4140 PF13600.1 CAM65686.1 - 1.8 9.0 6.8 11 6.4 1.2 2.9 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) VWA_2 PF13519.1 CAM65687.1 - 3.1e-10 40.4 0.3 3.1e-10 40.4 0.2 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain UIM PF02809.15 CAM65687.1 - 0.00022 20.5 15.3 0.0068 15.8 2.5 3.5 3 0 0 3 3 3 2 Ubiquitin interaction motif Ssl1 PF04056.9 CAM65687.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Ssl1-like Herpes_TAF50 PF03326.8 CAM65687.1 - 0.48 9.3 6.8 0.78 8.6 4.7 1.3 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Miro PF08477.8 CAM65688.1 - 0.00011 22.6 0.0 0.00018 21.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CAM65688.1 - 0.0059 16.5 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CAM65688.1 - 0.096 11.9 0.1 0.16 11.2 0.1 1.4 1 1 0 1 1 1 0 Ferrous iron transport protein B PMSR PF01625.16 CAM65689.1 - 5.2e-57 192.0 0.3 6.6e-57 191.7 0.2 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase RE_AlwI PF09491.5 CAM65689.1 - 0.018 13.5 0.0 0.024 13.1 0.0 1.0 1 0 0 1 1 1 0 AlwI restriction endonuclease PRiA4_ORF3 PF07929.6 CAM65689.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Plasmid pRiA4b ORF-3-like protein Chorein_N PF12624.2 CAM65690.2 - 1.7e-06 27.5 0.0 4.8e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Aa_trans PF01490.13 CAM65691.1 - 5.3e-58 196.4 23.9 6.1e-58 196.2 16.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CAM65691.1 - 2.1e-10 40.0 10.7 2.1e-10 40.0 7.4 2.0 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family EVC2_like PF12297.3 CAM65691.1 - 1.1 7.8 2.1 1.8 7.0 0.2 2.0 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein Cytochrome-c551 PF10643.4 CAM65691.1 - 1.4 8.1 5.0 3.9 6.6 3.5 1.7 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 PsbT PF01405.12 CAM65691.1 - 2.3 7.8 7.0 0.36 10.4 1.1 2.5 2 0 0 2 2 2 0 Photosystem II reaction centre T protein Pkinase PF00069.20 CAM65694.1 - 7e-56 189.2 0.0 1.1e-55 188.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM65694.1 - 1.3e-35 122.7 0.0 1.2e-34 119.5 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase PX PF00787.19 CAM65694.1 - 0.0038 17.0 0.0 0.0093 15.7 0.0 1.6 1 0 0 1 1 1 1 PX domain RuvA_N PF01330.16 CAM65694.1 - 0.046 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 RuvA N terminal domain Kinase-like PF14531.1 CAM65694.1 - 0.14 11.1 0.0 0.26 10.2 0.0 1.4 1 0 0 1 1 1 0 Kinase-like JAB PF01398.16 CAM65698.1 - 0.024 14.3 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF3539 PF12058.3 CAM65698.1 - 0.037 13.8 0.0 0.28 11.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3539) E1-E2_ATPase PF00122.15 CAM65699.2 - 6.6e-55 185.6 0.8 1.1e-54 184.8 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CAM65699.2 - 1.5e-23 84.3 0.0 1.3e-22 81.2 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 CAM65699.2 - 3e-23 82.2 0.0 7.3e-23 81.0 0.0 1.7 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.21 CAM65699.2 - 2.3e-14 52.6 0.0 4.7e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CAM65699.2 - 4.2e-11 43.3 0.0 1.2e-10 41.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CAM65699.2 - 5.4e-11 42.2 0.0 1.2e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CAM65699.2 - 8.1e-06 25.5 0.1 0.00032 20.3 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SMC_N PF02463.14 CAM65700.1 - 7e-63 211.7 0.0 1e-62 211.2 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CAM65700.1 - 8.2e-26 90.3 0.3 3.8e-25 88.1 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CAM65700.1 - 1.4e-14 54.7 0.2 7.4e-06 26.1 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 CAM65700.1 - 8e-08 32.8 30.8 8e-08 32.8 21.4 5.3 2 2 0 2 2 1 1 AAA domain AAA_15 PF13175.1 CAM65700.1 - 2.9e-05 23.3 11.8 0.01 14.8 6.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 CAM65700.1 - 7.5e-05 22.1 0.0 0.00016 21.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain BLOC1_2 PF10046.4 CAM65700.1 - 0.013 15.6 4.8 0.013 15.6 3.3 8.4 5 3 3 9 9 9 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ABC_tran PF00005.22 CAM65700.1 - 0.053 13.8 19.0 0.44 10.8 0.0 5.5 3 2 0 3 3 2 0 ABC transporter Mst1_SARAH PF11629.3 CAM65700.1 - 0.33 10.8 12.2 0.037 13.8 0.4 4.3 3 0 0 3 3 3 0 C terminal SARAH domain of Mst1 DASH_Dam1 PF08653.5 CAM65700.1 - 0.57 9.9 2.2 43 3.9 0.3 3.8 4 0 0 4 4 4 0 DASH complex subunit Dam1 DUF4250 PF14056.1 CAM65700.1 - 6.8 6.4 10.5 1.1 8.9 0.0 4.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4250) Synaptobrevin PF00957.16 CAM65702.1 - 2.5e-30 103.8 5.1 4.2e-30 103.1 3.5 1.4 1 0 0 1 1 1 1 Synaptobrevin EMP24_GP25L PF01105.19 CAM65702.1 - 0.0081 15.8 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Longin PF13774.1 CAM65702.1 - 0.02 14.4 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 Regulated-SNARE-like domain LRR19-TM PF15176.1 CAM65702.1 - 0.048 13.3 0.9 7.2 6.3 0.5 2.3 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain T2SF PF00482.18 CAM65702.1 - 0.19 11.6 1.3 0.35 10.7 0.9 1.5 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F Baculo_11_kDa PF06143.6 CAM65702.1 - 1.9 7.9 7.3 4.4 6.7 4.9 1.7 1 1 0 1 1 1 0 Baculovirus 11 kDa family His_Phos_1 PF00300.17 CAM65705.1 - 1.4e-32 112.9 0.0 1.6e-32 112.7 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ASCH PF04266.9 CAM65706.1 - 3.1e-16 59.6 0.1 1.7e-15 57.3 0.0 2.1 2 0 0 2 2 2 1 ASCH domain zf-C2HC5 PF06221.8 CAM65706.1 - 1.5e-11 43.8 7.5 3.3e-11 42.7 5.2 1.6 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type DEAD PF00270.24 CAM65707.1 - 5.2e-34 117.1 0.0 8.8e-34 116.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM65707.1 - 4.6e-19 68.0 0.0 1.1e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAM65707.1 - 0.00049 19.9 0.0 0.0017 18.1 0.0 1.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CAM65707.1 - 0.0011 19.0 0.0 0.0048 17.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain SecA_DEAD PF07517.9 CAM65707.1 - 0.009 15.3 0.0 0.15 11.3 0.0 2.2 2 0 0 2 2 2 1 SecA DEAD-like domain SNF2_N PF00176.18 CAM65707.1 - 0.018 13.8 0.0 0.032 13.0 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain Adaptin_N PF01602.15 CAM65708.1 - 1.7e-78 264.2 0.0 2.1e-78 263.9 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 CAM65708.1 - 1.4e-05 25.2 2.5 0.13 12.5 0.2 4.3 3 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.2 CAM65708.1 - 0.0088 15.9 0.0 3 7.6 0.0 2.6 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 CAM65708.1 - 0.01 16.1 0.0 0.27 11.6 0.0 2.6 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region HEAT PF02985.17 CAM65708.1 - 0.028 14.4 10.8 1.3 9.2 0.1 5.5 5 0 0 5 5 5 0 HEAT repeat DUF2435 PF10363.4 CAM65708.1 - 0.081 12.8 0.1 0.24 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2435) Proteasom_PSMB PF10508.4 CAM65708.1 - 0.22 9.7 1.0 0.56 8.4 0.1 1.8 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit HEAT_EZ PF13513.1 CAM65708.1 - 2.7 8.5 13.1 3.5 8.2 0.3 5.2 5 1 0 5 5 5 0 HEAT-like repeat DSPc PF00782.15 CAM65709.1 - 1.4e-28 99.1 0.0 2.8e-28 98.1 0.0 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.8 CAM65709.1 - 0.0012 18.2 0.1 1.4 8.3 0.0 3.0 3 0 0 3 3 3 2 Tyrosine phosphatase family Y_phosphatase PF00102.22 CAM65709.1 - 0.021 14.1 0.1 0.043 13.1 0.0 1.5 2 0 0 2 2 2 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CAM65709.1 - 0.032 14.2 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Init_tRNA_PT PF04179.7 CAM65709.1 - 0.063 12.1 0.0 0.09 11.6 0.0 1.2 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase WEMBL PF05701.6 CAM65710.1 - 0.00028 19.4 9.0 0.00057 18.4 6.3 1.4 1 0 0 1 1 1 1 Weak chloroplast movement under blue light SCP-1 PF05483.7 CAM65710.1 - 0.0012 16.7 5.3 0.002 16.0 3.6 1.3 1 0 0 1 1 1 1 Synaptonemal complex protein 1 (SCP-1) CENP-Q PF13094.1 CAM65710.1 - 0.0097 15.9 7.8 0.035 14.1 5.4 2.0 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF904 PF06005.7 CAM65710.1 - 0.019 15.2 1.4 0.019 15.2 1.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF904) Phage_GP20 PF06810.6 CAM65710.1 - 0.036 13.5 6.8 0.076 12.4 4.7 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 TBPIP PF07106.8 CAM65710.1 - 0.088 12.3 5.8 0.27 10.7 1.6 2.6 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Filament PF00038.16 CAM65710.1 - 0.1 12.0 11.3 0.22 10.9 5.7 2.1 1 1 1 2 2 2 0 Intermediate filament protein BLOC1_2 PF10046.4 CAM65710.1 - 0.14 12.2 4.7 0.28 11.3 0.6 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IncA PF04156.9 CAM65710.1 - 0.16 11.5 14.1 3.6 7.1 9.8 2.7 1 1 0 1 1 1 0 IncA protein CorA PF01544.13 CAM65710.1 - 0.66 8.9 5.0 1.4 7.9 3.4 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF1664 PF07889.7 CAM65710.1 - 0.92 9.3 5.4 6.3 6.6 0.4 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DivIVA PF05103.8 CAM65710.1 - 2.2 8.3 8.1 63 3.6 4.7 3.4 1 1 1 2 2 2 0 DivIVA protein GAS PF13851.1 CAM65710.1 - 2.2 7.4 10.6 3.6 6.7 3.2 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FYVE_2 PF02318.11 CAM65712.1 - 0.00041 20.2 8.0 0.00081 19.2 5.6 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger EF-hand_6 PF13405.1 CAM65713.1 - 0.00057 19.5 0.0 0.0081 15.9 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 CAM65713.1 - 0.054 12.8 0.0 0.16 11.3 0.0 1.8 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.27 CAM65713.1 - 0.054 12.8 0.0 0.22 10.8 0.0 2.1 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.1 CAM65713.1 - 0.099 12.7 0.0 0.49 10.5 0.0 2.0 3 0 0 3 3 3 0 EF-hand domain pair ERCC4 PF02732.10 CAM65714.1 - 2.7e-15 56.3 0.0 2.2e-14 53.4 0.0 2.3 2 0 0 2 2 2 1 ERCC4 domain PIG-H PF10181.4 CAM65715.1 - 3.6e-15 55.3 0.1 5.5e-15 54.7 0.1 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component LRR_8 PF13855.1 CAM65717.1 - 1.1e-07 31.5 2.0 0.14 11.8 0.0 4.9 3 2 2 5 5 5 4 Leucine rich repeat LRR_4 PF12799.2 CAM65717.1 - 9e-07 28.3 0.4 0.014 14.9 0.0 5.5 5 1 3 8 8 8 3 Leucine Rich repeats (2 copies) Med3 PF11593.3 CAM65717.1 - 0.35 10.0 7.7 0.51 9.5 5.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal LRR_1 PF00560.28 CAM65717.1 - 0.73 10.1 13.4 2.2 8.6 0.1 6.5 7 2 0 7 7 7 0 Leucine Rich Repeat LRR_7 PF13504.1 CAM65717.1 - 0.83 10.1 13.7 1.8 9.1 0.0 6.5 7 0 0 7 7 7 0 Leucine rich repeat LRR_6 PF13516.1 CAM65717.1 - 4.7 7.5 5.8 13 6.2 0.0 4.3 4 0 0 4 4 4 0 Leucine Rich repeat Hexapep PF00132.19 CAM65718.1 - 4e-15 54.5 5.0 0.00026 20.3 0.0 3.3 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CAM65718.1 - 0.023 14.2 9.3 0.17 11.4 1.5 3.3 2 1 2 4 4 4 0 Hexapeptide repeat of succinyl-transferase Exo_endo_phos PF03372.18 CAM65720.1 - 1.3e-17 64.5 0.0 2.2e-17 63.8 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CAM65720.1 - 0.02 14.5 0.0 0.061 12.9 0.0 1.8 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase ThiF PF00899.16 CAM65722.1 - 2.7e-31 108.1 0.2 1.8e-30 105.5 0.2 2.2 1 1 0 1 1 1 1 ThiF family UAE_UbL PF14732.1 CAM65722.1 - 2e-25 88.6 0.0 3.4e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBACT PF02134.16 CAM65722.1 - 2.1e-21 75.2 0.4 2.1e-21 75.2 0.3 2.1 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CAM65722.1 - 5e-16 57.7 1.5 2.1e-15 55.8 1.3 1.9 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 CAM65722.1 - 0.012 15.7 0.1 0.046 13.8 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ABC1 PF03109.11 CAM65723.1 - 3.7e-28 97.8 0.0 8e-28 96.8 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 CAM65723.1 - 5.1e-05 23.1 0.4 0.00019 21.2 0.3 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Ribosomal_L9_N PF01281.14 CAM65724.1 - 1.2e-05 24.4 0.0 2.9e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain DUF1180 PF06679.7 CAM65725.1 - 0.02 14.7 0.5 0.026 14.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF4591 PF15261.1 CAM65726.1 - 4.6e-05 23.6 2.9 0.044 14.0 0.0 3.4 2 1 0 2 2 2 2 Domain of unknown function (DUF4591) Ribosomal_L2_C PF03947.13 CAM65728.1 - 5.1e-19 68.3 0.1 8.4e-19 67.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Sod_Fe_C PF02777.13 CAM65729.1 - 2.9e-37 126.7 0.2 8e-37 125.3 0.0 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 CAM65729.1 - 4.5e-20 71.6 0.2 1.1e-19 70.4 0.1 1.7 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Isochorismatase PF00857.15 CAM65730.1 - 1.1e-13 51.4 0.0 6e-13 49.1 0.0 1.9 1 1 0 1 1 1 1 Isochorismatase family Isochorismatase PF00857.15 CAM65731.1 - 1.5e-10 41.2 0.1 3.3e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 Isochorismatase family Isochorismatase PF00857.15 CAM65732.1 - 1.1e-12 48.2 0.2 5.3e-12 46.0 0.1 1.8 1 1 0 1 1 1 1 Isochorismatase family zf-Tim10_DDP PF02953.10 CAM65733.1 - 9e-19 66.5 0.2 1.2e-18 66.1 0.1 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 CAM65733.1 - 0.0034 16.8 0.2 0.005 16.3 0.1 1.4 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) LANC_like PF05147.8 CAM65734.1 - 0.085 11.3 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein Defensin_big PF14862.1 CAM65736.1 - 0.068 13.2 0.4 0.068 13.2 0.3 2.3 2 0 0 2 2 2 0 Big defensin WD40 PF00400.27 CAM65741.1 - 1.4e-33 113.5 29.0 3.4e-10 39.4 0.0 10.9 11 0 0 11 11 11 7 WD domain, G-beta repeat PQQ_2 PF13360.1 CAM65741.1 - 3.8e-05 23.2 2.9 0.00069 19.1 0.2 3.6 3 1 1 4 4 4 2 PQQ-like domain BBS2_Mid PF14783.1 CAM65741.1 - 0.0018 18.0 0.6 1.2 8.9 0.0 4.8 5 2 1 6 6 6 1 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.6 CAM65741.1 - 0.014 15.1 0.0 4.1 7.0 0.0 3.2 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A eIF-6 PF01912.13 CAM65742.1 - 0.35 9.9 0.0 0.6 9.1 0.0 1.2 1 0 0 1 1 1 0 eIF-6 family Peptidase_S24 PF00717.18 CAM65745.1 - 6.5e-11 41.7 0.1 1.2e-10 40.8 0.0 1.5 1 1 0 1 1 1 1 Peptidase S24-like ABA_GPCR PF12430.3 CAM65745.1 - 0.023 13.8 0.3 0.69 9.0 0.0 2.1 2 0 0 2 2 2 0 Abscisic acid G-protein coupled receptor Rad60-SLD PF11976.3 CAM65747.1 - 2e-25 88.2 0.1 2.5e-25 87.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CAM65747.1 - 1.2e-08 34.2 0.0 1.5e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Pribosyl_synth PF14572.1 CAM65751.1 - 3.8e-22 78.9 2.6 6.1e-22 78.2 0.2 2.2 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 CAM65751.1 - 1.8e-19 69.5 0.6 2.6e-17 62.6 0.0 2.8 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase SPX PF03105.14 CAM65751.1 - 0.00017 21.4 5.0 0.00022 21.1 0.9 2.3 1 1 0 2 2 2 1 SPX domain Pribosyltran PF00156.22 CAM65751.1 - 0.049 13.3 0.0 0.3 10.8 0.0 2.3 2 0 0 2 2 2 0 Phosphoribosyl transferase domain Pkinase PF00069.20 CAM65752.1 - 9e-10 38.1 0.0 0.0006 19.0 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAM65752.1 - 1.3e-07 30.9 0.0 0.0012 18.0 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.20 CAM65753.1 - 6.4e-39 133.6 0.0 5.5e-26 91.2 0.0 3.8 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CAM65753.1 - 5.9e-16 58.3 0.0 2.8e-06 26.5 0.0 3.4 3 1 0 3 3 3 3 Protein tyrosine kinase Complex1_LYR PF05347.10 CAM65754.1 - 0.0067 16.1 0.9 0.0067 16.1 0.6 3.0 4 0 0 4 4 4 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CAM65754.1 - 0.011 15.8 0.7 0.011 15.8 0.5 2.1 2 0 0 2 2 2 0 Complex1_LYR-like CMAS PF02353.15 CAM65755.1 - 9.8e-75 251.1 0.0 1.4e-74 250.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 CAM65755.1 - 7.3e-13 48.5 0.0 1.4e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CAM65755.1 - 2.2e-11 44.0 0.0 5.2e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAM65755.1 - 5.5e-11 42.7 0.0 1.4e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAM65755.1 - 1.9e-09 37.8 0.0 6.2e-09 36.2 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAM65755.1 - 6.1e-09 36.4 0.0 2.3e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAM65755.1 - 3.4e-07 29.9 0.0 6e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CAM65755.1 - 2.5e-06 26.9 0.0 7.7e-06 25.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 CAM65755.1 - 5e-05 23.3 0.0 0.00033 20.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.7 CAM65755.1 - 0.00072 18.9 0.0 0.0019 17.6 0.0 1.7 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.14 CAM65755.1 - 0.0011 18.4 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 CAM65755.1 - 0.0024 16.9 0.0 0.0042 16.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase NodS PF05401.6 CAM65755.1 - 0.0031 16.9 0.0 0.0052 16.2 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.1 CAM65755.1 - 0.0041 16.8 0.0 0.0066 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 CAM65755.1 - 0.013 14.7 0.0 0.023 13.8 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB FtsJ PF01728.14 CAM65755.1 - 0.022 14.7 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase eIF-5_eIF-2B PF01873.12 CAM65756.1 - 4.2e-24 84.5 0.8 6.8e-24 83.9 0.5 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 PDE8 PF08629.5 CAM65756.1 - 0.086 12.6 1.7 0.21 11.4 1.2 1.6 1 0 0 1 1 1 0 PDE8 phosphodiesterase Cytochrom_c3_2 PF14537.1 CAM65756.1 - 0.094 13.0 1.4 0.26 11.6 0.2 2.3 3 0 0 3 3 3 0 Cytochrome c3 CDC37_N PF03234.9 CAM65756.1 - 0.45 10.8 7.0 0.046 14.0 1.2 2.0 2 1 0 2 2 2 0 Cdc37 N terminal kinase binding TFIIA PF03153.8 CAM65756.1 - 0.84 9.4 11.1 1.1 9.0 7.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Img2 PF05046.9 CAM65757.1 - 0.00042 20.4 0.0 0.00069 19.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) DUF1049 PF06305.6 CAM65758.1 - 0.025 14.0 0.1 0.049 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) MLANA PF14991.1 CAM65759.1 - 0.029 14.3 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein melan-A Protocadherin PF08374.6 CAM65759.1 - 0.029 13.9 0.0 0.04 13.5 0.0 1.1 1 0 0 1 1 1 0 Protocadherin ASFV_J13L PF05568.6 CAM65759.1 - 0.042 13.3 0.1 0.058 12.9 0.1 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF4079 PF13301.1 CAM65759.1 - 0.06 13.3 0.2 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) DUF1856 PF08983.5 CAM65759.1 - 0.24 11.5 3.7 0.44 10.6 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1856) Vpu PF00558.14 CAM65759.1 - 0.81 9.2 2.4 1.5 8.4 1.7 1.4 1 0 0 1 1 1 0 Vpu protein DUF3592 PF12158.3 CAM65759.1 - 1.7 8.4 5.6 8.4 6.1 4.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3592) DUF3180 PF11377.3 CAM65760.1 - 0.068 13.0 0.5 0.068 13.0 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3180) Prominin PF05478.6 CAM65761.1 - 0.0018 15.8 0.1 0.0022 15.6 0.0 1.1 1 0 0 1 1 1 1 Prominin DUF1469 PF07332.6 CAM65761.1 - 0.0021 17.8 0.4 0.74 9.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1469) Cytochrom_B_N_2 PF13631.1 CAM65761.1 - 0.0063 16.3 0.6 0.0079 16.0 0.4 1.1 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Yip1 PF04893.12 CAM65761.1 - 0.0072 15.8 0.7 0.0092 15.4 0.5 1.1 1 0 0 1 1 1 1 Yip1 domain MFS_2 PF13347.1 CAM65761.1 - 0.015 13.7 0.2 0.019 13.4 0.1 1.0 1 0 0 1 1 1 0 MFS/sugar transport protein 7tm_1 PF00001.16 CAM65761.1 - 0.02 14.0 0.1 0.024 13.7 0.0 1.0 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) ABC2_membrane_4 PF12730.2 CAM65761.1 - 0.021 14.0 0.7 0.027 13.6 0.5 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4231 PF14015.1 CAM65761.1 - 0.021 14.7 0.1 0.031 14.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) NfeD PF01957.13 CAM65761.1 - 0.023 14.8 0.1 0.03 14.4 0.1 1.2 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF4131 PF13567.1 CAM65761.1 - 0.026 13.9 2.3 0.046 13.1 1.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) IncA PF04156.9 CAM65761.1 - 0.032 13.8 1.3 0.58 9.7 0.0 2.0 2 0 0 2 2 2 0 IncA protein NrfD PF03916.9 CAM65761.1 - 0.036 13.4 2.0 0.051 12.9 1.4 1.2 1 0 0 1 1 1 0 Polysulphide reductase, NrfD OATP PF03137.15 CAM65761.1 - 0.036 12.1 0.0 0.036 12.1 0.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family WBP-1 PF11669.3 CAM65761.1 - 0.041 13.9 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 WW domain-binding protein 1 UPF0370 PF13980.1 CAM65761.1 - 0.041 13.6 0.1 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) BPD_transp_2 PF02653.11 CAM65761.1 - 0.041 12.8 0.5 0.041 12.8 0.4 2.0 1 1 1 2 2 2 0 Branched-chain amino acid transport system / permease component DUF21 PF01595.15 CAM65761.1 - 0.075 12.3 0.4 0.098 11.9 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF21 CopD PF05425.8 CAM65761.1 - 0.08 13.1 3.8 0.58 10.3 2.7 2.0 1 1 0 1 1 1 0 Copper resistance protein D DUF2140 PF09911.4 CAM65761.1 - 0.1 11.7 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) HemY_N PF07219.8 CAM65761.1 - 0.12 11.9 0.7 0.3 10.6 0.0 1.9 2 0 0 2 2 2 0 HemY protein N-terminus DUF3995 PF13160.1 CAM65761.1 - 0.18 11.8 6.7 0.27 11.3 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3995) DUF4381 PF14316.1 CAM65761.1 - 0.18 11.8 0.0 0.18 11.8 0.0 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF4381) VirB8 PF04335.8 CAM65761.1 - 0.24 10.9 1.7 9.9 5.6 0.0 2.1 2 0 0 2 2 2 0 VirB8 protein FtsX PF02687.16 CAM65761.1 - 0.32 10.7 5.6 0.41 10.3 3.2 1.7 1 1 1 2 2 2 0 FtsX-like permease family QCR10 PF09796.4 CAM65761.1 - 0.32 10.6 3.4 1 9.0 2.3 1.7 1 1 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DUF2749 PF10907.3 CAM65761.1 - 0.42 10.5 0.0 0.42 10.5 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2749) DUF1049 PF06305.6 CAM65761.1 - 1 8.9 6.0 0.36 10.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DctQ PF04290.7 CAM65761.1 - 1.6 8.4 7.7 2.8 7.6 1.8 1.5 1 1 1 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component RskA PF10099.4 CAM65761.1 - 2.8 7.6 5.3 4.3 7.0 1.4 2.0 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF2839 PF10999.3 CAM65761.1 - 9.6 6.3 7.0 0.56 10.2 1.0 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF2839) Amastin PF07344.6 CAM65764.1 - 2.6e-06 27.1 7.3 4.5e-06 26.3 5.1 1.4 1 0 0 1 1 1 1 Amastin surface glycoprotein DnaJ PF00226.26 CAM65765.1 - 1.6e-17 62.9 0.1 2.5e-17 62.3 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain DUF2360 PF10152.4 CAM65765.1 - 2.2 8.5 8.0 2 8.6 1.3 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Pkinase PF00069.20 CAM65766.1 - 4.1e-19 68.7 0.0 9.6e-19 67.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM65766.1 - 1.2e-11 44.1 0.0 3.2e-11 42.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 CAM65766.1 - 0.024 13.5 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 HAMP PF00672.20 CAM65766.1 - 0.27 11.4 3.3 1.1 9.4 2.3 2.2 1 1 0 1 1 1 0 HAMP domain AAA_16 PF13191.1 CAM65772.1 - 3.1e-08 33.8 0.0 9e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 CAM65772.1 - 0.00015 21.5 0.0 0.00031 20.5 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 CAM65772.1 - 0.0016 18.5 0.1 0.0073 16.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CAM65772.1 - 0.0029 17.4 0.0 0.006 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 CAM65772.1 - 0.0078 15.7 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.8 CAM65772.1 - 0.026 13.4 0.0 0.051 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Adeno_IVa2 PF02456.10 CAM65772.1 - 0.035 12.7 0.0 0.063 11.9 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein Miro PF08477.8 CAM65772.1 - 0.067 13.6 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein Oleosin PF01277.12 CAM65772.1 - 0.1 12.1 0.4 0.57 9.7 0.0 2.3 2 0 0 2 2 2 0 Oleosin AAA_16 PF13191.1 CAM65773.1 - 0.00023 21.2 0.1 0.00074 19.5 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain Ub-Mut7C PF14451.1 CAM65773.1 - 0.025 14.0 0.1 0.084 12.4 0.0 1.9 2 0 0 2 2 2 0 Mut7-C ubiquitin Arch_ATPase PF01637.13 CAM65773.1 - 0.057 13.1 0.0 0.15 11.7 0.0 1.6 2 0 0 2 2 2 0 Archaeal ATPase Zeta_toxin PF06414.7 CAM65773.1 - 0.062 12.3 0.0 0.12 11.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.1 CAM65773.1 - 0.067 13.3 0.1 0.43 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 CAM65773.1 - 0.078 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.1 CAM65773.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Amastin PF07344.6 CAM65775.1 - 8.4e-55 184.6 12.5 9.9e-55 184.3 8.7 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF4064 PF13273.1 CAM65775.1 - 0.019 15.0 0.2 0.019 15.0 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Claudin_2 PF13903.1 CAM65775.1 - 0.61 9.7 18.3 0.017 14.8 8.1 1.7 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction SUR7 PF06687.7 CAM65775.1 - 0.74 9.3 18.7 0.93 9.0 2.9 3.0 3 0 0 3 3 3 0 SUR7/PalI family DUF2165 PF09933.4 CAM65775.1 - 1.4 8.6 6.2 0.23 11.2 1.3 1.8 2 0 0 2 2 2 0 Predicted small integral membrane protein (DUF2165) DUF4293 PF14126.1 CAM65775.1 - 1.7 8.5 8.3 6.9 6.5 5.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) PMP22_Claudin PF00822.15 CAM65775.1 - 4.4 6.9 19.6 1.4e+02 2.0 9.0 4.3 1 1 2 3 3 3 0 PMP-22/EMP/MP20/Claudin family Amastin PF07344.6 CAM65777.1 - 5.3e-55 185.2 9.4 6.1e-55 185.0 6.5 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CAM65777.1 - 1.1 8.8 12.7 0.084 12.5 5.3 1.7 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF2165 PF09933.4 CAM65777.1 - 1.4 8.6 7.4 0.082 12.6 1.3 1.7 2 0 0 2 2 2 0 Predicted small integral membrane protein (DUF2165) DUF4220 PF13968.1 CAM65777.1 - 3 6.8 6.4 1.6 7.7 1.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4220) Amastin PF07344.6 CAM65779.1 - 5.7e-58 194.9 6.8 6.9e-58 194.6 4.7 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF4064 PF13273.1 CAM65779.1 - 0.012 15.6 1.1 0.32 11.1 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) TM140 PF14985.1 CAM65779.1 - 0.021 14.5 2.2 0.037 13.7 1.5 1.4 1 0 0 1 1 1 0 TM140 protein family Claudin_2 PF13903.1 CAM65779.1 - 3.4 7.3 11.3 0.2 11.3 3.6 2.0 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF2408 PF10303.4 CAM65782.1 - 0.029 14.4 0.4 0.082 13.0 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Toxin_44 PF15523.1 CAM65782.1 - 0.032 14.1 0.7 0.032 14.1 0.5 2.4 2 0 0 2 2 2 0 Putative toxin 44 CotJB PF12652.2 CAM65782.1 - 0.26 11.3 14.3 0.89 9.6 2.3 4.8 4 1 1 5 5 5 0 CotJB protein DUF1178 PF06676.6 CAM65782.1 - 3.6 7.7 10.1 3.3 7.9 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1178) SET PF00856.23 CAM65783.1 - 8.3e-10 39.2 0.1 5.5e-08 33.2 0.3 3.0 2 2 0 2 2 2 1 SET domain DNA_pol_B_thumb PF14791.1 CAM65784.1 - 8.3e-20 70.2 0.0 2.4e-19 68.7 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 CAM65784.1 - 1e-17 64.1 0.0 2.2e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.4 CAM65784.1 - 3.1e-15 55.4 0.1 1.1e-14 53.7 0.0 2.0 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 CAM65784.1 - 1.1e-13 51.1 0.2 9e-12 45.0 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_5 PF14520.1 CAM65784.1 - 0.0031 17.6 0.0 0.22 11.6 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_3 PF12836.2 CAM65784.1 - 0.12 12.3 0.1 9.9 6.1 0.0 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix motif DNA_pol_B_palm PF14792.1 CAM65785.1 - 1.3e-25 89.6 0.0 2.8e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 CAM65785.1 - 2.5e-18 65.5 0.3 5.2e-09 35.6 0.0 3.5 4 0 0 4 4 4 2 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 CAM65785.1 - 3e-10 39.5 0.0 4.3e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 Fingers domain of DNA polymerase lambda NTP_transf_2 PF01909.18 CAM65785.1 - 0.0063 16.8 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Lactamase_B_2 PF12706.2 CAM65786.1 - 4.6e-17 62.2 0.0 5.1e-15 55.5 0.0 3.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 CAM65786.1 - 1.5e-05 24.3 0.0 3.9e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 CAM65786.1 - 0.0031 17.2 0.4 0.013 15.1 0.1 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Dpy-30 PF05186.8 CAM65791.1 - 1.2e-06 27.8 0.1 2.7e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Dpy-30 motif DUF2453 PF10507.4 CAM65792.1 - 1.1e-37 128.2 1.9 3.2e-37 126.7 1.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2453) T2SF PF00482.18 CAM65792.1 - 0.056 13.3 1.8 13 5.7 0.1 3.0 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F DnaJ PF00226.26 CAM65794.1 - 2.4e-18 65.5 5.6 1.7e-09 37.2 0.1 3.1 2 1 1 3 3 3 2 DnaJ domain MMPL PF03176.10 CAM65794.1 - 0.029 13.0 0.3 0.058 12.0 0.2 1.4 1 0 0 1 1 1 0 MMPL family DUF3854 PF12965.2 CAM65794.1 - 0.032 13.8 0.1 0.27 10.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3854) Peptidase_C1 PF00112.18 CAM65796.1 - 4.9e-62 209.6 2.9 4.9e-62 209.6 2.0 2.5 2 1 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 CAM65796.1 - 4.6e-11 42.8 0.8 7.1e-11 42.2 0.5 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 CAM65796.1 - 2.5e-05 23.0 0.2 0.0027 16.3 0.0 2.3 2 0 0 2 2 2 2 Peptidase C1-like family Hist_deacetyl PF00850.14 CAM65798.1 - 5.6e-59 199.9 0.0 8.5e-59 199.3 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain cwf21 PF08312.7 CAM65799.1 - 0.0045 16.8 0.1 0.04 13.7 0.0 2.7 3 1 0 3 3 3 1 cwf21 domain SnAC PF14619.1 CAM65799.1 - 0.089 12.9 0.3 0.089 12.9 0.2 2.5 3 0 0 3 3 3 0 Snf2-ATP coupling, chromatin remodelling complex TPR_11 PF13414.1 CAM65800.1 - 3.4e-67 222.0 26.1 5.5e-19 67.5 0.4 6.4 5 1 0 6 6 6 6 TPR repeat TPR_1 PF00515.23 CAM65800.1 - 4.4e-54 177.9 34.7 4e-08 32.5 0.0 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.12 CAM65800.1 - 1.3e-43 143.3 35.0 1.1e-05 24.9 0.0 9.8 10 0 0 10 10 9 9 Tetratricopeptide repeat TPR_16 PF13432.1 CAM65800.1 - 8e-27 93.2 8.2 0.00017 22.1 0.0 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.1 CAM65800.1 - 2.9e-21 75.1 23.6 4.1e-09 36.2 0.6 6.5 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 CAM65800.1 - 1.2e-18 65.8 7.0 0.057 14.0 0.0 9.5 5 3 5 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.1 CAM65800.1 - 1.4e-18 66.9 8.1 0.0036 17.6 0.0 6.7 4 2 1 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 CAM65800.1 - 8.4e-18 62.7 19.7 0.029 14.1 0.0 8.6 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.1 CAM65800.1 - 1.5e-15 56.0 16.0 0.11 12.7 0.2 8.5 8 0 0 8 8 8 5 Tetratricopeptide repeat Apc3 PF12895.2 CAM65800.1 - 1.9e-13 50.3 25.3 8.2e-06 25.8 4.1 5.5 3 3 3 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 CAM65800.1 - 6.1e-13 47.5 12.8 0.023 14.4 0.1 8.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 CAM65800.1 - 2.4e-11 43.2 1.4 0.00068 19.4 0.0 6.0 4 2 2 6 6 6 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CAM65800.1 - 4.4e-07 29.6 5.9 1.1 9.1 0.0 6.2 7 0 0 7 7 7 2 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 CAM65800.1 - 0.00023 21.0 12.4 3.3 7.7 0.1 7.2 8 0 0 8 8 7 1 Tetratricopeptide repeat MIT PF04212.13 CAM65800.1 - 0.00072 19.3 23.8 1.3 8.9 0.1 7.2 6 1 0 7 7 7 2 MIT (microtubule interacting and transport) domain TPR_20 PF14561.1 CAM65800.1 - 0.0012 18.8 1.3 2.3 8.3 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 CAM65800.1 - 0.0028 16.8 11.2 0.53 9.5 0.0 5.6 7 0 0 7 7 7 1 SHNi-TPR TPR_6 PF13174.1 CAM65800.1 - 0.019 15.4 26.0 8.3 7.1 0.1 8.8 9 0 0 9 9 8 0 Tetratricopeptide repeat DUF3856 PF12968.2 CAM65800.1 - 0.072 12.9 7.6 5.8 6.7 0.1 5.0 3 3 0 3 3 3 0 Domain of Unknown Function (DUF3856) DUF1126 PF06565.7 CAM65801.1 - 2.2e-16 59.0 0.0 5.1e-11 41.8 0.0 3.6 3 0 0 3 3 3 3 Repeat of unknown function (DUF1126) EF-hand_1 PF00036.27 CAM65801.1 - 0.0015 17.6 0.0 0.0044 16.2 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 CAM65801.1 - 0.01 15.4 0.0 0.038 13.6 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.1 CAM65801.1 - 0.032 13.5 0.0 0.081 12.3 0.0 1.7 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 CAM65801.1 - 0.032 14.1 0.0 0.27 11.2 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain Pribosyltran_N PF13793.1 CAM65802.1 - 2.7e-35 120.5 0.0 6e-35 119.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 CAM65802.1 - 1.6e-23 83.4 0.5 5.6e-23 81.6 0.2 1.8 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 CAM65802.1 - 1.7e-13 50.4 1.7 5e-13 48.8 1.2 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CAM65802.1 - 0.0058 15.8 0.1 0.011 14.9 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Sec3_C PF09763.4 CAM65804.1 - 3.3e-77 260.2 3.6 5.6e-38 130.5 0.3 2.2 2 0 0 2 2 2 2 Exocyst complex component Sec3 IncA PF04156.9 CAM65804.1 - 0.046 13.3 9.1 0.12 11.9 6.3 1.6 1 0 0 1 1 1 0 IncA protein TPMT PF05724.6 CAM65805.1 - 1.3e-16 60.7 0.0 2.7e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.1 CAM65805.1 - 0.0014 18.3 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FAST_1 PF06743.10 CAM65806.1 - 0.032 13.9 0.3 1.3 8.8 0.0 3.3 3 1 1 4 4 4 0 FAST kinase-like protein, subdomain 1 PhageMin_Tail PF10145.4 CAM65806.1 - 1.4 8.5 6.9 4.1 6.9 0.1 3.6 3 1 0 4 4 4 0 Phage-related minor tail protein Slu7 PF11708.3 CAM65807.1 - 0.0004 20.2 1.6 0.0011 18.7 0.6 2.1 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_3 PF13917.1 CAM65807.1 - 0.0057 16.3 0.6 0.017 14.8 0.4 1.8 1 0 0 1 1 1 1 Zinc knuckle BTK PF00779.14 CAM65807.1 - 0.015 14.8 2.9 0.031 13.9 2.0 1.5 1 0 0 1 1 1 0 BTK motif zf-CCHC_5 PF14787.1 CAM65807.1 - 0.091 12.2 1.4 0.16 11.4 1.0 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DUF639 PF04842.7 CAM65807.1 - 0.11 10.6 0.2 0.15 10.1 0.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) DUF3586 PF12131.3 CAM65807.1 - 8 6.5 9.7 0.37 10.8 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3586) Coatomer_WDAD PF04053.9 CAM65808.1 - 4.9e-10 38.7 2.2 0.00047 19.0 0.1 4.2 5 0 0 5 5 5 2 Coatomer WD associated region WD40 PF00400.27 CAM65808.1 - 1.3e-06 28.0 9.7 0.65 9.9 0.0 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat TPR_7 PF13176.1 CAM65808.1 - 2.5e-05 23.7 6.1 0.042 13.6 0.3 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat Clathrin PF00637.15 CAM65808.1 - 0.0042 16.7 2.5 1.2 8.6 0.1 3.9 2 1 1 3 3 3 1 Region in Clathrin and VPS zf-RanBP PF00641.13 CAM65808.1 - 0.0048 15.9 10.2 0.01 14.8 1.9 2.8 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others eIF2A PF08662.6 CAM65808.1 - 0.025 14.3 0.0 0.21 11.2 0.0 2.4 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Vps39_1 PF10366.4 CAM65808.1 - 0.031 14.2 0.3 0.11 12.5 0.2 1.9 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 TPR_12 PF13424.1 CAM65808.1 - 0.096 12.6 16.4 0.41 10.6 0.1 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat DZR PF12773.2 CAM65808.1 - 0.34 10.7 13.1 2.7 7.8 9.1 2.5 1 1 0 1 1 1 0 Double zinc ribbon TPR_1 PF00515.23 CAM65808.1 - 1.1 9.0 10.4 0.96 9.1 0.3 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 CAM65808.1 - 1.2 9.2 20.6 0.81 9.7 0.7 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 CAM65808.1 - 2.7 7.6 19.9 0.3 10.7 0.3 4.9 5 0 0 5 5 5 0 TPR repeat Tubulin PF00091.20 CAM65816.1 - 7.4e-70 235.1 0.0 1.2e-69 234.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CAM65816.1 - 6.4e-48 161.9 0.1 9.7e-48 161.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CAM65816.1 - 2.7e-05 24.1 0.0 6.1e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CAM65816.1 - 0.0076 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.20 CAM65817.1 - 2.8e-70 236.5 0.0 4.5e-70 235.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CAM65817.1 - 6.4e-48 161.9 0.1 9.7e-48 161.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CAM65817.1 - 5.6e-05 23.1 0.0 0.00013 21.9 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CAM65817.1 - 0.0078 15.6 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Hist_deacetyl PF00850.14 CAM65818.1 - 1e-76 258.2 0.3 2.3e-45 155.2 0.3 2.1 2 0 0 2 2 2 2 Histone deacetylase domain Smoothelin PF12510.3 CAM65819.1 - 0.011 15.5 3.5 1.5 8.7 0.6 2.4 2 0 0 2 2 2 0 Smoothelin cytoskeleton protein HTH_12 PF08461.5 CAM65823.1 - 0.025 14.2 0.6 0.051 13.2 0.4 1.5 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain Tropomyosin PF00261.15 CAM65823.1 - 0.052 12.6 0.5 0.052 12.6 0.4 1.7 2 0 0 2 2 2 0 Tropomyosin Tropomyosin_1 PF12718.2 CAM65823.1 - 0.2 11.4 3.4 0.25 11.2 0.4 2.0 2 0 0 2 2 2 0 Tropomyosin like WD40 PF00400.27 CAM65824.1 - 0.12 12.2 8.4 2.4 8.1 0.0 4.5 4 0 0 4 4 4 0 WD domain, G-beta repeat Suf PF05843.9 CAM65826.1 - 0.12 12.0 0.0 1.5 8.4 0.0 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) PEX11 PF05648.9 CAM65827.1 - 1.1e-09 37.9 5.6 2e-07 30.5 3.9 2.5 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PIG-L PF02585.12 CAM65828.1 - 9.1e-25 87.6 0.0 1.2e-24 87.2 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase HhH-GPD PF00730.20 CAM65829.1 - 1.4e-20 73.5 0.0 2.1e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 CAM65829.1 - 8.6e-07 28.3 0.0 2.3e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.4 CAM65829.1 - 1.7e-05 24.7 4.1 3.4e-05 23.8 2.8 1.5 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III HHH_5 PF14520.1 CAM65829.1 - 0.0031 17.6 0.1 0.25 11.5 0.0 2.0 1 1 1 2 2 2 2 Helix-hairpin-helix domain CRS1_YhbY PF01985.16 CAM65829.1 - 0.034 14.1 0.3 0.077 13.0 0.2 1.5 1 0 0 1 1 1 0 CRS1 / YhbY (CRM) domain RRM_1 PF00076.17 CAM65830.1 - 1.2e-20 72.8 0.0 1.6e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM65830.1 - 1.4e-16 60.2 0.0 2.2e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM65830.1 - 2.8e-08 33.4 0.0 4.3e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rogdi_lz PF10259.4 CAM65830.1 - 0.049 12.7 0.0 0.06 12.4 0.0 1.1 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein RNA_bind PF08675.6 CAM65830.1 - 0.067 13.1 0.0 0.16 11.9 0.0 1.6 2 0 0 2 2 2 0 RNA binding domain HA2 PF04408.18 CAM65831.1 - 1.2e-17 63.7 0.3 9.5e-17 60.8 0.0 2.6 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CAM65831.1 - 2.3e-12 46.7 0.0 5.8e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CAM65831.1 - 1.6e-11 43.8 0.1 3.7e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAM65831.1 - 2.8e-10 39.9 0.1 8e-10 38.4 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase RWD PF05773.17 CAM65831.1 - 1.1e-05 25.3 0.0 4.2e-05 23.4 0.0 2.0 1 0 0 1 1 1 1 RWD domain T2SE PF00437.15 CAM65831.1 - 2.6e-05 23.2 0.0 5.3e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 CAM65831.1 - 6.5e-05 23.0 0.2 0.00089 19.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain zf-CCHC PF00098.18 CAM65831.1 - 0.00018 21.2 1.8 0.00018 21.2 1.2 2.8 2 0 0 2 2 2 1 Zinc knuckle Zeta_toxin PF06414.7 CAM65831.1 - 0.015 14.4 0.1 0.042 12.9 0.0 1.7 1 1 0 1 1 1 0 Zeta toxin ResIII PF04851.10 CAM65831.1 - 0.019 14.7 0.1 1.6 8.4 0.0 2.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.1 CAM65831.1 - 0.024 14.6 1.3 0.38 10.7 0.5 3.2 2 1 0 2 2 2 0 AAA ATPase domain Sigma54_activ_2 PF14532.1 CAM65831.1 - 0.11 12.5 0.0 0.53 10.3 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain KaiC PF06745.8 CAM65831.1 - 0.11 11.5 0.0 0.28 10.2 0.0 1.6 1 0 0 1 1 1 0 KaiC SRP54 PF00448.17 CAM65831.1 - 0.14 11.5 0.5 4.7 6.6 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RRM_1 PF00076.17 CAM65832.1 - 6.5e-19 67.3 0.0 1e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM65832.1 - 2.8e-14 52.8 0.0 5.1e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM65832.1 - 9.7e-09 34.9 0.0 1.7e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAM65833.1 - 2.2e-16 59.2 0.0 3.4e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM65833.1 - 2.5e-09 36.9 0.0 4.2e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM65833.1 - 1.8e-06 27.6 0.0 3.5e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ifi-6-16 PF06140.8 CAM65833.1 - 0.017 14.8 0.3 0.017 14.8 0.2 2.4 3 0 0 3 3 3 0 Interferon-induced 6-16 family EF-hand_7 PF13499.1 CAM65834.1 - 1.5e-09 37.8 3.0 1.5e-09 37.8 2.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CAM65834.1 - 2.6e-07 29.4 3.9 0.0056 15.8 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 CAM65834.1 - 1.1e-06 28.1 0.6 0.00077 19.0 0.4 2.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CAM65834.1 - 9.6e-05 21.9 2.4 0.28 11.1 0.2 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 CAM65834.1 - 0.061 12.6 1.3 0.12 11.7 0.0 2.3 2 1 0 2 2 2 0 EF hand Fib_alpha PF08702.5 CAM65834.1 - 2.4 8.2 22.1 0.97 9.5 0.4 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family APG6 PF04111.7 CAM65834.1 - 4.5 6.2 43.5 4 6.3 1.0 3.2 1 1 1 3 3 3 0 Autophagy protein Apg6 Reo_sigmaC PF04582.7 CAM65834.1 - 5.8 5.9 9.9 15 4.6 0.5 2.9 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Tropomyosin PF00261.15 CAM65834.1 - 6.9 5.6 64.0 1.5 7.8 9.4 3.4 1 1 1 2 2 2 0 Tropomyosin DUF3584 PF12128.3 CAM65834.1 - 9.6 3.3 63.4 0.12 9.7 21.1 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) Kinesin PF00225.18 CAM65837.1 - 2.7e-76 256.4 0.0 9.9e-45 152.6 0.0 2.9 2 1 0 2 2 2 2 Kinesin motor domain AAA_22 PF13401.1 CAM65837.1 - 0.058 13.5 0.0 0.058 13.5 0.0 3.1 3 1 0 3 3 3 0 AAA domain DUF87 PF01935.12 CAM65837.1 - 0.063 13.0 0.0 0.063 13.0 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function DUF87 FHA PF00498.21 CAM65838.1 - 4.1e-14 52.4 0.1 8.3e-14 51.4 0.1 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 CAM65838.1 - 6.7e-07 29.0 13.2 6.7e-07 29.0 9.1 3.2 3 1 0 3 3 2 1 Ring finger domain zf-C3HC4 PF00097.20 CAM65838.1 - 8.5e-07 28.5 11.9 8.5e-07 28.5 8.3 2.9 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAM65838.1 - 2.9e-06 26.9 12.0 2.9e-06 26.9 8.3 3.4 4 0 0 4 4 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CAM65838.1 - 1.5e-05 24.8 13.9 1.5e-05 24.8 9.6 3.8 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CAM65838.1 - 8.4e-05 22.3 12.1 8.4e-05 22.3 8.4 3.3 3 1 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 CAM65838.1 - 9.8e-05 22.0 7.0 9.8e-05 22.0 4.9 3.2 3 1 0 3 3 2 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 CAM65838.1 - 0.018 14.7 10.6 0.059 13.0 7.3 2.0 1 0 0 1 1 1 0 RING-type zinc-finger Vps39_2 PF10367.4 CAM65838.1 - 0.052 13.7 0.4 0.052 13.7 0.3 2.3 2 0 0 2 2 1 0 Vacuolar sorting protein 39 domain 2 zf-Nse PF11789.3 CAM65838.1 - 0.066 12.7 5.3 0.17 11.4 3.7 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zinc_ribbon_4 PF13717.1 CAM65838.1 - 1.9 8.2 15.4 2.2 8.0 3.8 4.0 3 0 0 3 3 3 0 zinc-ribbon domain Atg8 PF02991.11 CAM65839.1 - 6.2e-06 26.1 0.0 1.1e-05 25.3 0.0 1.4 1 1 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Atg8 PF02991.11 CAM65840.1 - 7.9e-06 25.7 0.0 1.4e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Oxidored_q6 PF01058.17 CAM65840.1 - 0.09 12.3 1.6 0.3 10.6 0.0 2.1 2 0 0 2 2 2 0 NADH ubiquinone oxidoreductase, 20 Kd subunit Atg8 PF02991.11 CAM65841.1 - 6.2e-06 26.1 0.0 1.1e-05 25.3 0.0 1.4 1 1 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Atg8 PF02991.11 CAM65842.1 - 5.8e-06 26.2 0.0 1e-05 25.4 0.0 1.4 1 1 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like NRDE PF05742.7 CAM65844.2 - 1.7e-14 53.7 0.0 1.7e-12 47.2 0.0 3.2 4 0 0 4 4 4 1 NRDE protein DUF4586 PF15239.1 CAM65845.1 - 2.5e-36 125.7 4.5 3.2e-36 125.4 3.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) Kinesin PF00225.18 CAM65847.2 - 2.4e-30 105.3 0.1 9.3e-11 40.9 0.0 3.9 4 0 0 4 4 4 3 Kinesin motor domain Pkinase PF00069.20 CAM65849.1 - 1.9e-49 168.1 0.0 5.2e-49 166.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM65849.1 - 9.5e-22 77.3 0.2 1.9e-20 73.0 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM65849.1 - 4.7e-07 29.0 0.0 1.5e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CAM65849.1 - 0.00011 22.0 0.0 0.00011 22.0 0.0 2.7 2 2 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 CAM65849.1 - 0.044 12.8 0.0 0.1 11.6 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CAM65849.1 - 0.046 13.0 0.0 0.4 9.9 0.0 2.2 2 0 0 2 2 2 0 RIO1 family DUF2833 PF11090.3 CAM65850.1 - 0.16 12.1 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2833) DUF2833 PF11090.3 CAM65851.1 - 0.15 12.2 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2833) DUF3040 PF11239.3 CAM65851.1 - 0.67 10.0 3.3 3.9 7.5 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF1500 PF07389.7 CAM65852.1 - 0.076 13.0 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1500) zf-RING_2 PF13639.1 CAM65854.1 - 1.2e-09 37.8 11.3 3.4e-09 36.3 5.2 2.5 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 CAM65854.1 - 1.1e-07 31.8 3.1 2.1e-07 30.9 0.7 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CAM65854.1 - 8.1e-05 22.2 6.2 8.1e-05 22.2 4.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAM65854.1 - 8.9e-05 22.4 8.2 8.9e-05 22.4 5.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CAM65854.1 - 0.00034 20.1 3.0 0.00034 20.1 2.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CAM65854.1 - 0.00038 20.2 1.6 0.00096 18.9 1.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 CAM65854.1 - 0.0019 17.8 5.5 0.0019 17.8 3.8 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CAM65854.1 - 3.8 7.4 9.5 0.88 9.5 3.7 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FAD_binding_7 PF03441.9 CAM65855.1 - 8.3e-45 153.1 0.4 1.2e-44 152.6 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 CAM65855.1 - 6.3e-20 71.5 0.3 4.1e-19 68.9 0.1 2.4 2 0 0 2 2 2 1 DNA photolyase Ank_2 PF12796.2 CAM65856.1 - 7.4e-08 32.6 0.0 1.3e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CAM65856.1 - 4.6e-07 30.1 0.0 1.4e-06 28.6 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 CAM65856.1 - 1.5e-05 24.5 0.0 0.00097 18.8 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 CAM65856.1 - 5.3e-05 23.0 0.5 0.0016 18.4 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 CAM65856.1 - 0.0071 16.5 0.4 0.028 14.6 0.0 2.2 2 1 0 2 2 2 1 Ankyrin repeats (many copies) DUF1631 PF07793.6 CAM65857.1 - 0.039 12.1 0.9 0.05 11.7 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) DUF202 PF02656.10 CAM65858.2 - 0.00025 21.1 0.8 0.00025 21.1 0.6 3.1 4 0 0 4 4 4 1 Domain of unknown function (DUF202) MASE1 PF05231.9 CAM65858.2 - 0.0059 15.6 0.7 0.013 14.5 0.5 1.5 1 0 0 1 1 1 1 MASE1 Ferric_reduct PF01794.14 CAM65858.2 - 0.043 13.8 2.2 0.2 11.7 1.5 2.0 1 1 1 2 2 2 0 Ferric reductase like transmembrane component DUF4199 PF13858.1 CAM65858.2 - 0.056 13.3 0.3 0.11 12.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Pox_G7 PF05503.7 CAM65859.1 - 0.29 9.7 0.0 0.47 9.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus G7-like Pkinase PF00069.20 CAM65860.1 - 4.2e-50 170.3 0.0 5.4e-50 169.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM65860.1 - 1.7e-16 60.0 0.0 2.5e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CAM65860.1 - 0.05 13.3 2.7 1.2 8.7 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 CAM65860.1 - 0.064 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 CAM65861.1 - 4.4e-50 170.2 0.0 5.7e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM65861.1 - 1.8e-16 59.9 0.0 2.6e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CAM65861.1 - 0.055 13.2 2.7 1.3 8.7 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 CAM65861.1 - 0.064 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DSPn PF14671.1 CAM65862.2 - 1.8e-20 73.3 0.0 2.1e-13 50.4 0.0 2.4 2 0 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 CAM65862.2 - 2.7e-08 33.4 0.1 5.2e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CAM65862.2 - 0.00016 21.1 0.0 0.00025 20.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CAM65862.2 - 0.087 13.0 0.4 0.2 11.8 0.3 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 CAM65862.2 - 0.39 10.7 0.8 0.85 9.6 0.5 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate zf-C3HC4_3 PF13920.1 CAM65863.1 - 2.4e-10 39.9 15.4 3.7e-10 39.3 10.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Plus-3 PF03126.13 CAM65863.1 - 9.4e-08 32.0 0.0 2.2e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Plus-3 domain zf-C3HC4_2 PF13923.1 CAM65863.1 - 0.52 10.3 18.2 0.91 9.6 12.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CAM65863.1 - 2.9 7.8 16.5 5.9 6.8 11.5 1.6 1 0 0 1 1 1 0 Ring finger domain TPR_11 PF13414.1 CAM65864.1 - 5e-24 83.7 12.5 3.5e-08 32.9 0.0 7.0 4 1 3 8 8 8 7 TPR repeat TPR_1 PF00515.23 CAM65864.1 - 8.9e-16 56.7 14.9 0.0024 17.4 0.0 9.1 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.1 CAM65864.1 - 3.7e-15 55.0 9.4 0.028 15.0 0.0 7.3 5 1 2 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.12 CAM65864.1 - 1.9e-14 52.3 14.1 0.068 13.1 0.0 9.2 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.1 CAM65864.1 - 2e-11 42.7 0.2 0.82 9.5 0.0 6.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 CAM65864.1 - 2.4e-10 40.8 9.4 0.13 12.9 0.1 7.0 6 1 1 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.1 CAM65864.1 - 3.4e-09 36.4 5.6 0.00011 21.9 0.3 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 CAM65864.1 - 2.5e-08 33.7 20.6 0.0029 17.5 0.0 6.7 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 CAM65864.1 - 6.1e-07 29.6 8.9 0.049 13.9 0.2 5.6 3 2 4 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 CAM65864.1 - 0.00016 21.9 6.1 10 6.8 0.0 5.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 CAM65864.1 - 0.001 19.0 9.5 16 6.0 0.0 7.8 10 0 0 10 10 9 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CAM65864.1 - 0.021 14.6 9.3 0.16 11.8 0.0 4.8 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.1 CAM65864.1 - 0.14 12.0 5.2 87 3.2 0.1 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 CAM65864.1 - 3.4 7.7 10.4 35 4.4 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat P-mevalo_kinase PF04275.9 CAM65865.1 - 0.05 13.3 0.5 4.8 6.9 0.2 2.6 2 0 0 2 2 2 0 Phosphomevalonate kinase Herpes_IE2_3 PF03361.9 CAM65865.1 - 0.16 11.2 0.7 0.38 10.0 0.5 1.5 1 0 0 1 1 1 0 Herpes virus intermediate/early protein 2/3 Metallophos PF00149.23 CAM65867.1 - 1.3e-23 83.4 1.8 1.8e-23 83.0 1.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Herpes_BLRF2 PF05812.7 CAM65867.1 - 0.035 13.8 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein DUF1192 PF06698.6 CAM65867.1 - 0.076 12.8 0.9 0.17 11.7 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) IRK PF01007.15 CAM65868.1 - 2.2e-05 23.4 1.0 0.013 14.2 0.0 3.1 3 0 0 3 3 3 3 Inward rectifier potassium channel LRR_8 PF13855.1 CAM65873.1 - 0.00063 19.4 8.6 1.5 8.6 0.0 5.5 4 2 2 6 6 6 3 Leucine rich repeat LRR_1 PF00560.28 CAM65873.1 - 0.00089 18.9 1.3 1.7 9.0 0.0 5.2 4 1 1 5 5 5 1 Leucine Rich Repeat LRR_6 PF13516.1 CAM65873.1 - 0.0025 17.7 1.9 1.9 8.7 0.0 4.7 4 0 0 4 4 4 1 Leucine Rich repeat LRR_7 PF13504.1 CAM65873.1 - 0.0075 16.2 10.9 11 6.7 0.0 7.1 6 0 0 6 6 6 1 Leucine rich repeat LRR_4 PF12799.2 CAM65873.1 - 0.01 15.4 4.2 3.1 7.5 0.0 5.3 4 2 0 4 4 4 0 Leucine Rich repeats (2 copies) AAA_2 PF07724.9 CAM65876.1 - 6.5e-42 143.3 0.2 1.3e-33 116.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 CAM65876.1 - 1e-12 48.3 0.5 6.8e-05 23.0 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 CAM65876.1 - 1.7e-06 27.8 0.1 8.6e-06 25.5 0.0 2.3 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 CAM65876.1 - 3.5e-06 26.7 0.1 7.4e-05 22.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CAM65876.1 - 2.3e-05 24.5 0.0 0.0022 18.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CAM65876.1 - 4.5e-05 24.2 0.0 0.0012 19.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CAM65876.1 - 0.00019 21.4 0.9 0.005 16.8 0.6 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 CAM65876.1 - 0.00094 19.4 0.0 0.038 14.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain MCM PF00493.18 CAM65876.1 - 0.0013 17.5 0.1 0.057 12.2 0.0 2.3 2 0 0 2 2 2 1 MCM2/3/5 family ATP-synt_ab PF00006.20 CAM65876.1 - 0.002 17.6 0.1 0.0037 16.7 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Mg_chelatase PF01078.16 CAM65876.1 - 0.013 14.7 0.7 0.053 12.6 0.0 2.4 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CAM65876.1 - 0.015 14.8 0.0 0.17 11.3 0.0 2.6 2 1 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 CAM65876.1 - 0.02 14.0 0.6 0.12 11.4 0.3 2.3 1 1 0 1 1 1 0 Zeta toxin AAA_14 PF13173.1 CAM65876.1 - 0.038 13.9 0.1 9.6 6.1 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CAM65876.1 - 0.073 12.9 0.1 0.45 10.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 CAM65876.1 - 0.077 13.2 0.0 0.55 10.5 0.0 2.2 2 0 0 2 2 2 0 ABC transporter ResIII PF04851.10 CAM65876.1 - 0.081 12.7 0.0 0.84 9.4 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit MobB PF03205.9 CAM65876.1 - 0.083 12.5 0.0 0.39 10.4 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B UCH PF00443.24 CAM65877.1 - 3.5e-39 134.5 0.0 1.4e-38 132.5 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CAM65877.1 - 5.9e-05 22.6 0.0 0.0055 16.1 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase MCM PF00493.18 CAM65878.1 - 4.3e-119 397.1 0.0 1.7e-118 395.2 0.0 1.9 1 1 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CAM65878.1 - 3.4e-13 50.1 0.0 1.8e-12 47.8 0.0 2.1 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 CAM65878.1 - 4.6e-09 36.1 0.0 9.7e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CAM65878.1 - 5e-08 32.3 0.2 1.2e-05 24.6 0.0 2.8 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CAM65878.1 - 0.00094 18.6 0.0 0.042 13.3 0.0 2.8 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 CAM65878.1 - 0.0028 17.2 0.0 0.007 15.9 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Med31 PF05669.7 CAM65878.1 - 0.14 11.9 0.1 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 SOH1 G10 PF01125.12 CAM65879.1 - 2.7e-51 172.9 1.6 3.5e-47 159.6 0.9 2.1 2 0 0 2 2 2 2 G10 protein MFS_1 PF07690.11 CAM65880.1 - 3e-22 78.8 32.2 1.2e-16 60.4 7.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily VTC PF09359.5 CAM65881.1 - 6.5e-77 258.3 0.1 9.9e-77 257.7 0.1 1.3 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.10 CAM65881.1 - 0.00037 20.6 0.8 0.00037 20.6 0.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2910 PF11139.3 CAM65881.1 - 0.062 12.4 0.2 0.12 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2910) RinB PF06116.7 CAM65881.1 - 0.12 12.0 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Transcriptional activator RinB DSPc PF00782.15 CAM65882.1 - 2.5e-08 33.5 0.1 7.1e-07 28.8 0.0 2.3 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CAM65882.1 - 0.051 12.9 0.3 0.1 11.9 0.2 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase His_Phos_1 PF00300.17 CAM65883.1 - 3.6e-13 49.8 0.0 7.8e-13 48.8 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 CAM65883.1 - 0.0047 16.3 0.0 0.031 13.6 0.0 1.9 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) LRR_8 PF13855.1 CAM65885.1 - 5.3e-06 26.0 0.6 0.012 15.3 0.0 2.6 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 CAM65885.1 - 0.001 18.6 2.4 0.34 10.5 0.2 3.1 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CAM65885.1 - 0.0031 17.3 1.2 17 5.9 0.1 4.2 4 0 0 4 4 4 1 Leucine Rich Repeat UvrD-helicase PF00580.16 CAM65886.1 - 1.3e-38 133.1 0.0 7.2e-36 124.0 0.0 2.4 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 CAM65886.1 - 1.7e-27 96.7 0.0 1.2e-13 51.2 0.0 2.4 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 CAM65886.1 - 2e-13 49.8 1.1 7.4e-13 48.0 0.8 2.0 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 CAM65886.1 - 3.8e-09 36.6 0.0 1.8e-08 34.4 0.0 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.1 CAM65886.1 - 1.4e-07 31.3 1.6 6.5e-05 22.6 0.2 2.5 2 0 0 2 2 2 2 AAA domain Peptidase_S51 PF03575.12 CAM65887.1 - 7.1e-19 68.0 0.0 7.5e-17 61.4 0.0 2.2 1 1 0 1 1 1 1 Peptidase family S51 PRKCSH-like PF12999.2 CAM65888.1 - 3.7e-08 33.1 0.1 4.3e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like DUF898 PF05987.8 CAM65888.1 - 0.077 11.8 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF913 PF06025.7 CAM65889.1 - 0.24 10.1 2.0 0.63 8.7 0.0 2.4 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) PH PF00169.24 CAM65890.2 - 5.3e-05 23.3 0.0 9.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_5 PF15405.1 CAM65890.2 - 0.19 11.6 0.2 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain zf-DHHC PF01529.15 CAM65891.1 - 1.7e-29 102.4 2.0 1.7e-29 102.4 1.4 2.7 2 2 0 2 2 2 1 DHHC palmitoyltransferase AAA_17 PF13207.1 CAM65892.1 - 2.4e-06 28.3 0.0 2e-05 25.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CAM65892.1 - 3.1e-06 27.1 0.3 2.1e-05 24.4 0.1 2.4 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CAM65892.1 - 1.1e-05 24.5 0.0 2.3e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 CAM65892.1 - 0.00082 19.6 0.1 0.0044 17.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.15 CAM65892.1 - 0.00094 18.8 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.1 CAM65892.1 - 0.0015 18.5 2.0 0.0048 16.9 0.4 2.5 2 1 0 2 2 2 1 AAA ATPase domain PRK PF00485.13 CAM65892.1 - 0.045 13.2 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.1 CAM65892.1 - 0.055 13.4 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CAM65892.1 - 0.13 12.5 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.1 CAM65892.1 - 0.14 12.3 0.0 1.1 9.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 CAM65892.1 - 0.25 10.2 0.0 0.39 9.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TYW3 PF02676.9 CAM65893.1 - 5.4e-41 139.9 0.0 1.3e-39 135.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase TYW3 Abhydrolase_6 PF12697.2 CAM65893.1 - 0.013 15.3 0.4 0.02 14.7 0.3 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Prefoldin_2 PF01920.15 CAM65894.1 - 3.2e-18 65.4 1.5 4e-18 65.1 1.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit DASH_Dad3 PF08656.5 CAM65894.1 - 0.0041 16.7 2.8 0.0052 16.4 0.6 1.9 2 0 0 2 2 2 1 DASH complex subunit Dad3 DUF939_C PF11728.3 CAM65894.1 - 0.048 13.4 0.8 0.14 11.9 0.1 1.9 2 0 0 2 2 2 0 DUF939 C-terminal domain TBPIP PF07106.8 CAM65894.1 - 0.051 13.1 2.9 0.52 9.8 0.3 2.2 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Microtub_bind PF13931.1 CAM65894.1 - 0.11 12.6 1.9 0.33 11.1 0.5 1.9 2 0 0 2 2 2 0 Kinesin-associated microtubule-binding DUF4037 PF13228.1 CAM65894.1 - 0.15 12.2 0.2 5.5 7.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4037) NTR2 PF15458.1 CAM65894.1 - 0.18 11.0 3.5 5.9 6.0 0.8 2.1 2 0 0 2 2 2 0 Nineteen complex-related protein 2 Spc24 PF08286.6 CAM65894.1 - 0.34 10.6 5.0 3.7 7.2 0.5 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 SlyX PF04102.7 CAM65894.1 - 0.35 11.2 4.1 1.2 9.5 0.1 2.5 2 1 0 2 2 2 0 SlyX DUF3835 PF12927.2 CAM65894.1 - 0.78 10.7 3.7 0.45 11.5 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3835) zf-CCCH PF00642.19 CAM65899.2 - 2.2e-16 59.0 31.1 0.00024 20.6 0.2 5.5 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCHC PF00098.18 CAM65899.2 - 5.9e-07 29.1 6.1 0.00013 21.6 0.4 3.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 CAM65899.2 - 2.7e-05 23.5 11.0 0.00032 20.1 0.6 3.2 2 0 0 2 2 2 2 Zinc knuckle zf-CCCH_2 PF14608.1 CAM65899.2 - 0.032 14.2 0.1 0.032 14.2 0.1 6.1 6 0 0 6 6 6 0 Zinc finger C-x8-C-x5-C-x3-H type zf-UBR PF02207.15 CAM65901.1 - 1.1e-16 60.2 12.9 1.1e-16 60.2 9.0 2.5 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) Rtf2 PF04641.7 CAM65901.1 - 5 6.2 11.2 1.3 8.1 0.5 2.4 2 0 0 2 2 2 0 Rtf2 RING-finger ACBP PF00887.14 CAM65902.1 - 2.1e-24 84.9 0.4 4.5e-24 83.9 0.2 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein DUF4486 PF14858.1 CAM65903.1 - 0.0028 15.9 0.0 0.0055 15.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4486) TK PF00265.13 CAM65903.1 - 1.5 8.3 0.1 2.9 7.4 0.0 1.3 1 0 0 1 1 1 0 Thymidine kinase Peptidase_S9_N PF02897.10 CAM65904.1 - 1.2e-121 406.2 0.2 1.5e-121 405.8 0.1 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 CAM65904.1 - 1e-66 224.1 0.0 1.6e-66 223.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF4464 PF14713.1 CAM65905.1 - 4.6e-83 278.2 0.2 5.4e-83 277.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) MT PF12777.2 CAM65907.1 - 9.6e-09 34.4 0.1 9.6e-09 34.4 0.0 4.8 3 2 1 5 5 5 1 Microtubule-binding stalk of dynein motor Prefoldin PF02996.12 CAM65908.1 - 1.2e-08 34.5 0.1 9e-08 31.7 0.0 2.1 2 0 0 2 2 2 1 Prefoldin subunit AAA PF00004.24 CAM65909.1 - 0.00011 22.3 0.0 0.00025 21.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 CAM65909.1 - 0.011 14.8 0.1 0.032 13.3 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.1 CAM65909.1 - 0.019 14.9 0.2 1 9.2 0.0 2.7 1 1 1 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 CAM65909.1 - 0.036 14.2 0.0 0.099 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain LrgB PF04172.11 CAM65909.1 - 0.32 10.1 0.9 0.55 9.3 0.6 1.3 1 0 0 1 1 1 0 LrgB-like family DEAD PF00270.24 CAM65910.1 - 8.8e-25 87.1 0.1 1.5e-24 86.4 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM65910.1 - 9.5e-18 63.8 0.0 4.8e-17 61.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAM65910.1 - 8.2e-05 22.5 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UPF0160 PF03690.8 CAM65911.1 - 1.4e-121 405.7 0.0 1.7e-121 405.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Ras PF00071.17 CAM65912.1 - 1.2e-34 119.0 0.0 1.5e-11 43.9 0.0 3.0 3 0 0 3 3 3 3 Ras family Miro PF08477.8 CAM65912.1 - 1.8e-09 38.1 0.0 7.1e-09 36.1 0.0 2.0 2 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 CAM65912.1 - 0.00015 21.0 0.0 0.72 9.0 0.0 2.9 3 0 0 3 3 3 2 ADP-ribosylation factor family AAA_22 PF13401.1 CAM65912.1 - 0.071 13.2 0.0 0.12 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain GPP34 PF05719.6 CAM65913.1 - 0.026 14.6 0.1 0.026 14.5 0.1 1.1 1 0 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) Nuc_deoxyrib_tr PF05014.10 CAM65914.1 - 1.1 9.1 3.5 3.1 7.7 2.5 1.7 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase Hydrolase PF00702.21 CAM65916.1 - 1e-13 52.2 0.4 1.3e-05 25.7 0.0 4.0 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase HAD PF12710.2 CAM65916.1 - 6e-09 36.3 0.0 1.1e-05 25.6 0.0 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CAM65916.1 - 1.1e-06 27.9 0.0 0.00028 19.9 0.0 2.8 2 0 0 2 2 2 2 E1-E2 ATPase Hydrolase_3 PF08282.7 CAM65916.1 - 0.015 14.8 0.1 0.031 13.8 0.1 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase ubiquitin PF00240.18 CAM65917.2 - 0 1130.1 53.3 2.3e-32 110.1 0.2 11.0 11 0 0 11 11 11 11 Ubiquitin family Rad60-SLD PF11976.3 CAM65917.2 - 6.7e-208 672.8 48.8 9.1e-19 66.9 0.2 11.0 11 0 0 11 11 11 11 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CAM65917.2 - 1.8e-59 197.9 21.2 0.00081 19.6 0.0 13.5 11 10 0 11 11 11 10 Ubiquitin-like domain Ribosomal_L40e PF01020.12 CAM65917.2 - 2.7e-32 110.0 11.5 5.4e-32 109.1 8.0 1.5 1 0 0 1 1 1 1 Ribosomal L40e family DUF2870 PF11069.3 CAM65917.2 - 6.7e-30 103.0 0.2 2.9 7.9 0.0 11.7 11 0 0 11 11 11 11 Protein of unknown function (DUF2870) Rad60-SLD_2 PF13881.1 CAM65917.2 - 4.4e-29 100.6 18.5 0.67 9.8 0.0 12.0 11 0 0 11 11 11 11 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CAM65917.2 - 9.1e-24 83.4 9.6 4.1 7.6 0.0 11.1 1 1 9 11 11 11 10 DUF2407 ubiquitin-like domain TUG-UBL1 PF11470.3 CAM65917.2 - 2.8e-19 68.8 14.0 5.9 6.8 0.0 10.6 11 0 0 11 11 11 10 GLUT4 regulating protein TUG FlgD_ig PF13860.1 CAM65917.2 - 1.1e-10 41.0 16.6 38 4.1 0.0 10.1 10 0 0 10 10 10 0 FlgD Ig-like domain USP7_C2 PF14533.1 CAM65917.2 - 1.4e-09 37.7 18.3 14 5.0 0.1 9.5 1 1 2 10 10 10 0 Ubiquitin-specific protease C-terminal CTDII PF01556.13 CAM65917.2 - 1.2e-06 28.2 39.7 17 5.3 0.1 10.2 1 1 8 10 10 10 0 DnaJ C terminal domain EF-hand_7 PF13499.1 CAM65918.1 - 7.8e-06 25.9 0.4 2.4e-05 24.3 0.2 2.0 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CAM65918.1 - 2.8e-05 23.6 0.1 0.00022 20.8 0.0 2.6 2 1 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 CAM65918.1 - 5.9e-05 22.0 4.7 0.00019 20.4 0.0 3.0 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.1 CAM65918.1 - 0.00017 21.1 1.1 0.0056 16.2 0.4 2.6 2 0 0 2 2 2 1 EF-hand domain pair DUF241 PF03087.9 CAM65918.1 - 0.0051 16.3 3.8 0.0064 16.0 2.7 1.2 1 0 0 1 1 1 1 Arabidopsis protein of unknown function EF-hand_5 PF13202.1 CAM65918.1 - 0.0078 15.5 0.0 0.0078 15.5 0.0 2.9 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.1 CAM65918.1 - 0.096 12.6 0.1 0.74 9.7 0.0 2.2 2 1 0 2 2 2 0 EF-hand domain YokU PF14122.1 CAM65918.1 - 0.18 11.5 3.5 1.7 8.4 1.0 2.6 1 1 0 2 2 2 0 YokU-like protein EF-hand_1 PF00036.27 CAM65919.1 - 5.9e-43 140.9 12.3 2e-10 39.2 0.7 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CAM65919.1 - 2.5e-38 130.0 4.2 2.2e-21 75.7 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CAM65919.1 - 2.2e-33 113.6 11.2 2.3e-16 59.1 0.5 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 CAM65919.1 - 2e-31 105.0 6.7 1.2e-09 37.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CAM65919.1 - 2.9e-29 99.0 8.0 1.7e-07 30.2 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 CAM65919.1 - 8.6e-15 54.4 0.1 7.5e-08 32.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CAM65919.1 - 1.1e-09 37.9 0.9 4.5e-05 23.1 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CAM65919.1 - 3e-08 33.6 0.0 0.00049 20.0 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 CAM65919.1 - 1.9e-06 27.3 1.8 0.18 11.4 0.0 3.9 4 1 1 5 5 5 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 CAM65919.1 - 4.8e-06 26.4 1.2 5.9e-05 22.9 0.2 2.3 2 0 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 CAM65919.1 - 0.00022 20.9 0.3 0.082 12.6 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 CAM65919.1 - 0.00025 20.6 0.1 0.013 15.0 0.1 2.5 1 1 0 1 1 1 1 Caleosin related protein EF-hand_like PF09279.6 CAM65919.1 - 0.00033 20.6 1.2 0.0031 17.5 0.1 2.4 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like RNA_pol_Rpb4 PF03874.11 CAM65919.1 - 0.0038 17.2 0.5 1.7 8.6 0.1 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb4 DUF1103 PF06513.6 CAM65919.1 - 0.0051 16.2 1.1 0.0059 16.0 0.8 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) MotA_activ PF09114.5 CAM65919.1 - 0.021 14.5 0.1 4.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Transcription factor MotA, activation domain Poly_export PF02563.11 CAM65919.1 - 0.042 13.6 0.2 11 5.8 0.0 3.1 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein LNS2 PF08235.8 CAM65919.1 - 0.045 13.3 0.1 0.33 10.4 0.0 1.9 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) Tenui_NCP PF04876.7 CAM65919.1 - 0.064 12.8 0.1 0.95 8.9 0.0 2.1 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein Toprim_2 PF13155.1 CAM65919.1 - 0.065 13.5 0.8 14 6.0 0.3 2.6 1 1 2 3 3 3 0 Toprim-like SpoVIF PF14069.1 CAM65919.1 - 0.077 12.7 0.8 1.6 8.5 0.1 2.6 3 0 0 3 3 3 0 Stage VI sporulation protein F DUF1880 PF08976.6 CAM65919.1 - 0.13 12.3 0.0 0.84 9.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) EF-hand_1 PF00036.27 CAM65920.1 - 5.9e-43 140.9 12.3 2e-10 39.2 0.7 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CAM65920.1 - 2.5e-38 130.0 4.2 2.2e-21 75.7 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CAM65920.1 - 2.2e-33 113.6 11.2 2.3e-16 59.1 0.5 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 CAM65920.1 - 2e-31 105.0 6.7 1.2e-09 37.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CAM65920.1 - 2.9e-29 99.0 8.0 1.7e-07 30.2 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 CAM65920.1 - 8.6e-15 54.4 0.1 7.5e-08 32.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CAM65920.1 - 1.1e-09 37.9 0.9 4.5e-05 23.1 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CAM65920.1 - 3e-08 33.6 0.0 0.00049 20.0 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 CAM65920.1 - 1.9e-06 27.3 1.8 0.18 11.4 0.0 3.9 4 1 1 5 5 5 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 CAM65920.1 - 4.8e-06 26.4 1.2 5.9e-05 22.9 0.2 2.3 2 0 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 CAM65920.1 - 0.00022 20.9 0.3 0.082 12.6 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 CAM65920.1 - 0.00025 20.6 0.1 0.013 15.0 0.1 2.5 1 1 0 1 1 1 1 Caleosin related protein EF-hand_like PF09279.6 CAM65920.1 - 0.00033 20.6 1.2 0.0031 17.5 0.1 2.4 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like RNA_pol_Rpb4 PF03874.11 CAM65920.1 - 0.0038 17.2 0.5 1.7 8.6 0.1 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb4 DUF1103 PF06513.6 CAM65920.1 - 0.0051 16.2 1.1 0.0059 16.0 0.8 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) MotA_activ PF09114.5 CAM65920.1 - 0.021 14.5 0.1 4.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Transcription factor MotA, activation domain Poly_export PF02563.11 CAM65920.1 - 0.042 13.6 0.2 11 5.8 0.0 3.1 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein LNS2 PF08235.8 CAM65920.1 - 0.045 13.3 0.1 0.33 10.4 0.0 1.9 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) Tenui_NCP PF04876.7 CAM65920.1 - 0.064 12.8 0.1 0.95 8.9 0.0 2.1 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein Toprim_2 PF13155.1 CAM65920.1 - 0.065 13.5 0.8 14 6.0 0.3 2.6 1 1 2 3 3 3 0 Toprim-like SpoVIF PF14069.1 CAM65920.1 - 0.077 12.7 0.8 1.6 8.5 0.1 2.6 3 0 0 3 3 3 0 Stage VI sporulation protein F DUF1880 PF08976.6 CAM65920.1 - 0.13 12.3 0.0 0.84 9.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) DUF3441 PF11923.3 CAM65921.1 - 7e-33 112.5 0.1 7e-33 112.5 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3441) FbpA PF05833.6 CAM65921.1 - 1.5e-32 112.7 9.8 4.4e-24 84.8 0.0 2.8 3 0 0 3 3 3 2 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 CAM65921.1 - 4.4e-06 26.5 0.0 0.00015 21.5 0.0 3.2 1 1 0 1 1 1 1 Domain of unknown function (DUF814) SLA_LP_auto_ag PF05889.8 CAM65922.1 - 1.2e-91 307.1 0.0 9e-52 175.8 0.0 3.6 3 1 0 3 3 3 3 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Beta_elim_lyase PF01212.16 CAM65922.1 - 4.2e-05 22.8 0.1 8.2e-05 21.8 0.1 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase DUF3783 PF12646.2 CAM65922.1 - 0.029 14.1 0.1 9.2 6.0 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3783) DUF3854 PF12965.2 CAM65922.1 - 0.12 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) EF1G PF00647.14 CAM65924.1 - 2.7e-46 155.7 0.3 8.8e-46 154.0 0.1 1.9 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 CAM65924.1 - 3e-12 46.3 1.7 4.6e-12 45.7 0.1 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CAM65924.1 - 1.3e-09 38.0 0.0 4.4e-09 36.4 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CAM65924.1 - 7.6e-06 26.0 0.0 1.7e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CAM65924.1 - 2.4e-05 24.1 0.0 6.1e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CAM65924.1 - 0.0002 21.7 0.1 0.0002 21.7 0.1 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain EF1G PF00647.14 CAM65925.1 - 1.9e-46 156.1 0.2 7.2e-46 154.3 0.1 2.0 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 CAM65925.1 - 1.9e-12 47.0 1.4 3.8e-12 46.0 0.1 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CAM65925.1 - 1e-09 38.4 0.0 3.7e-09 36.6 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CAM65925.1 - 6.5e-06 26.2 0.0 1.5e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CAM65925.1 - 1.9e-05 24.4 0.0 5.1e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CAM65925.1 - 0.00016 22.0 0.1 0.00016 22.0 0.1 2.3 3 1 1 4 4 4 1 Glutathione S-transferase, C-terminal domain PAM2 PF07145.10 CAM65926.1 - 0.018 14.4 3.9 0.32 10.5 0.0 3.1 3 0 0 3 3 3 0 Ataxin-2 C-terminal region Chorein_N PF12624.2 CAM65927.1 - 1.1e-22 79.8 0.0 2.1e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter EIAV_GP90 PF00971.13 CAM65927.1 - 4.1 5.7 0.1 6.7 5.0 0.1 1.2 1 0 0 1 1 1 0 EIAV coat protein, gp90 PUB PF09409.5 CAM65928.1 - 1.8e-12 46.8 0.1 3e-12 46.1 0.1 1.4 1 0 0 1 1 1 1 PUB domain NPCBM_assoc PF10633.4 CAM65929.1 - 0.0049 16.8 1.3 0.044 13.8 0.0 2.6 2 0 0 2 2 2 1 NPCBM-associated, NEW3 domain of alpha-galactosidase CDC50 PF03381.10 CAM65930.1 - 3.2e-80 269.2 0.1 4.7e-80 268.7 0.1 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Retinal PF15449.1 CAM65930.1 - 1.9 6.0 10.1 2.6 5.5 7.0 1.0 1 0 0 1 1 1 0 Retinal protein PTS_EIIB PF00367.15 CAM65931.1 - 0.016 14.4 0.2 0.039 13.1 0.1 1.5 1 0 0 1 1 1 0 phosphotransferase system, EIIB Exonuc_VII_L PF02601.10 CAM65931.1 - 0.022 13.9 4.9 0.032 13.4 3.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Cep57_CLD_2 PF14197.1 CAM65931.1 - 0.032 14.1 3.3 0.032 14.1 2.3 3.0 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Takusan PF04822.8 CAM65931.1 - 0.1 12.3 2.8 0.14 11.9 0.5 2.1 2 0 0 2 2 2 0 Takusan TMF_TATA_bd PF12325.3 CAM65931.1 - 1.4 8.6 6.3 0.21 11.3 0.3 2.4 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding GAS PF13851.1 CAM65931.1 - 4.3 6.4 7.8 21 4.2 4.3 2.3 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding LCAT PF02450.10 CAM65932.1 - 1.1e-45 156.3 0.0 1.6e-31 109.6 0.1 2.1 1 1 0 2 2 2 2 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 CAM65932.1 - 3e-05 24.0 0.3 7e-05 22.8 0.2 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CAM65932.1 - 0.0033 17.1 0.1 0.006 16.3 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Motile_Sperm PF00635.21 CAM65933.1 - 3.7e-11 42.6 0.0 6e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 MSP (Major sperm protein) domain SHS2_Rpb7-N PF03876.12 CAM65934.1 - 2.2e-25 88.5 0.0 3.7e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.7 CAM65934.1 - 1.8e-12 47.5 0.0 1.3e-06 28.5 0.0 2.1 2 0 0 2 2 2 2 RNA polymerase III subunit Rpc25 GTP_EFTU PF00009.22 CAM65935.1 - 3.6e-35 121.1 0.0 6.3e-35 120.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 CAM65935.1 - 2.4e-29 101.2 0.5 6.5e-29 99.8 0.1 2.0 2 0 0 2 2 2 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 CAM65935.1 - 1.1e-05 25.4 2.5 2e-05 24.5 0.7 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CAM65935.1 - 9.9e-05 22.2 0.0 0.00052 19.9 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CAM65935.1 - 0.022 14.5 0.1 0.55 10.0 0.0 2.5 2 0 0 2 2 2 0 Dynamin family Zn-ribbon_8 PF09723.5 CAM65935.1 - 0.075 13.0 4.6 0.17 11.8 3.2 1.6 1 0 0 1 1 1 0 Zinc ribbon domain NOB1_Zn_bind PF08772.6 CAM65935.1 - 0.23 11.2 1.7 0.61 9.9 1.2 1.7 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like GTP_EFTU PF00009.22 CAM65936.1 - 1.2e-35 122.6 0.1 1.9e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 CAM65936.1 - 1.8e-11 43.9 0.1 3.3e-10 39.8 0.0 2.7 3 0 0 3 3 3 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 CAM65936.1 - 0.00023 21.1 1.3 0.0033 17.5 0.9 2.5 1 1 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CAM65936.1 - 0.00098 19.0 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Zn-ribbon_8 PF09723.5 CAM65936.1 - 0.1 12.5 4.6 0.22 11.4 3.2 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Dynamin_N PF00350.18 CAM65936.1 - 0.11 12.2 0.1 0.73 9.6 0.0 2.1 2 0 0 2 2 2 0 Dynamin family Myosin_tail_1 PF01576.14 CAM65938.2 - 0.0054 14.5 12.8 0.0078 13.9 8.9 1.3 1 0 0 1 1 1 1 Myosin tail DUF4201 PF13870.1 CAM65938.2 - 0.01 15.2 10.0 0.23 10.8 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) WEMBL PF05701.6 CAM65938.2 - 0.016 13.7 12.4 0.025 13.0 8.6 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light CALCOCO1 PF07888.6 CAM65938.2 - 0.019 13.2 7.1 0.023 12.9 4.9 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like HALZ PF02183.13 CAM65938.2 - 0.063 13.0 8.1 27 4.5 0.1 4.3 4 0 0 4 4 4 0 Homeobox associated leucine zipper DUF1993 PF09351.5 CAM65938.2 - 0.12 12.3 8.2 0.05 13.5 4.2 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF1993) DivIVA PF05103.8 CAM65938.2 - 0.12 12.4 12.2 7.4 6.6 3.3 3.3 2 1 1 3 3 3 0 DivIVA protein Reo_sigmaC PF04582.7 CAM65938.2 - 0.13 11.3 5.8 0.14 11.3 3.1 1.6 1 1 1 2 2 2 0 Reovirus sigma C capsid protein IncA PF04156.9 CAM65938.2 - 0.2 11.2 12.7 0.19 11.2 7.7 1.8 1 1 0 1 1 1 0 IncA protein Scaffolding_pro PF11418.3 CAM65938.2 - 0.26 11.6 5.2 1.1 9.5 2.9 2.3 2 1 0 2 2 2 0 Phi29 scaffolding protein Cep57_CLD_2 PF14197.1 CAM65938.2 - 0.3 11.0 11.4 0.18 11.7 1.6 3.2 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Microtub_assoc PF07989.6 CAM65938.2 - 0.4 10.5 7.3 0.9 9.4 0.5 2.9 3 0 0 3 3 2 0 Microtubule associated DUF4407 PF14362.1 CAM65938.2 - 0.62 8.9 8.3 0.17 10.7 3.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Occludin_ELL PF07303.8 CAM65938.2 - 0.92 10.2 5.0 2.7 8.7 0.3 2.8 3 0 0 3 3 3 0 Occludin homology domain Kinetocho_Slk19 PF12709.2 CAM65938.2 - 0.95 9.5 8.3 6.7 6.8 0.2 3.7 2 1 2 4 4 4 0 Central kinetochore-associated Spectrin PF00435.16 CAM65938.2 - 1.3 9.3 13.5 6.6 7.0 5.0 2.8 2 1 1 3 3 3 0 Spectrin repeat DUF1151 PF06625.6 CAM65938.2 - 1.4 8.6 11.2 0.89 9.3 0.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1151) DUF904 PF06005.7 CAM65938.2 - 1.5 9.1 13.8 2.3 8.5 0.6 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF904) HalX PF08663.5 CAM65938.2 - 1.8 8.6 10.3 5.4 7.0 1.4 3.5 2 1 2 4 4 4 0 HalX domain TBPIP PF07106.8 CAM65938.2 - 2 7.9 12.0 2.5 7.5 1.4 3.2 2 2 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) V_ATPase_I PF01496.14 CAM65938.2 - 3 5.5 5.8 3.6 5.3 4.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fzo_mitofusin PF04799.8 CAM65938.2 - 3.1 7.1 7.8 11 5.3 1.1 2.8 2 1 1 3 3 3 0 fzo-like conserved region Mnd1 PF03962.10 CAM65938.2 - 3.9 7.1 15.6 2.6 7.6 1.5 2.7 1 1 1 3 3 3 0 Mnd1 family FUSC PF04632.7 CAM65938.2 - 3.9 5.8 12.5 6.4 5.0 8.7 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family SlyX PF04102.7 CAM65938.2 - 6.3 7.2 11.5 30 5.0 2.0 3.5 3 1 0 3 3 3 0 SlyX DUF2681 PF10883.3 CAM65938.2 - 6.5 7.0 8.7 0.97 9.6 0.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) DUF4570 PF15134.1 CAM65938.2 - 6.9 6.5 9.7 13 5.6 1.2 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4570) ERM PF00769.14 CAM65938.2 - 9 5.7 18.5 4.9 6.6 2.0 3.0 2 1 1 3 3 3 0 Ezrin/radixin/moesin family MRP PF09387.5 CAM65940.1 - 3.6e-73 245.4 1.3 4.4e-73 245.1 0.9 1.1 1 0 0 1 1 1 1 Mitochondrial RNA binding protein MRP Tim17 PF02466.14 CAM65941.1 - 6.5e-17 61.7 9.1 8.2e-17 61.4 6.3 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Cytochrom_B_N PF00033.14 CAM65941.1 - 0.0088 15.4 0.9 0.011 15.1 0.6 1.1 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB IncA PF04156.9 CAM65943.1 - 0.7 9.4 2.8 1.2 8.6 0.6 2.1 2 0 0 2 2 2 0 IncA protein RRM_1 PF00076.17 CAM65944.1 - 0.046 13.3 0.1 0.11 12.1 0.1 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DRAT PF07357.6 CAM65944.1 - 0.1 11.7 0.1 0.28 10.3 0.0 1.7 2 0 0 2 2 2 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) Skp1 PF01466.14 CAM65945.1 - 0.00029 20.7 2.9 0.0019 18.1 2.0 2.1 1 1 0 1 1 1 1 Skp1 family, dimerisation domain Skp1 PF01466.14 CAM65946.2 - 0.0042 17.0 1.1 0.011 15.7 0.1 2.1 2 1 0 2 2 2 1 Skp1 family, dimerisation domain Ank_5 PF13857.1 CAM65948.1 - 0.00024 21.2 1.4 0.0084 16.3 0.1 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 CAM65948.1 - 0.00075 19.7 0.7 0.0091 16.3 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CAM65948.1 - 0.0011 19.4 0.1 0.086 13.3 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 CAM65948.1 - 0.0022 17.7 0.1 0.0022 17.7 0.1 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 CAM65948.1 - 0.096 12.9 0.3 0.69 10.3 0.0 2.7 3 0 0 3 3 3 0 Ankyrin repeat zf-C3HC4_3 PF13920.1 CAM65949.1 - 1.1e-09 37.7 23.5 1.1e-09 37.7 16.3 2.7 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) AAA PF00004.24 CAM65950.1 - 5.1e-33 114.0 0.0 6.3e-22 78.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CAM65950.1 - 4.8e-09 36.4 0.2 0.00013 22.1 0.0 3.6 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 CAM65950.1 - 2.7e-08 34.0 2.8 6.8e-06 26.2 0.0 3.9 3 1 1 4 4 4 1 AAA ATPase domain AAA_19 PF13245.1 CAM65950.1 - 7.5e-08 32.0 0.0 0.00043 19.9 0.0 3.5 2 0 0 2 2 2 2 Part of AAA domain AAA_14 PF13173.1 CAM65950.1 - 6.5e-07 29.3 0.0 0.00012 21.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CAM65950.1 - 8.4e-07 28.9 0.0 0.0053 16.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain Zot PF05707.7 CAM65950.1 - 1.5e-06 27.8 1.1 0.049 13.0 0.1 4.0 2 2 0 2 2 2 2 Zonular occludens toxin (Zot) AAA_17 PF13207.1 CAM65950.1 - 6.4e-06 26.9 0.0 0.0078 17.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CAM65950.1 - 1.4e-05 24.6 0.0 0.0045 16.4 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein DUF2075 PF09848.4 CAM65950.1 - 3.8e-05 22.8 0.1 0.25 10.2 0.0 3.2 2 1 1 3 3 3 2 Uncharacterized conserved protein (DUF2075) TIP49 PF06068.8 CAM65950.1 - 4.6e-05 22.2 0.1 0.017 13.8 0.0 2.4 2 0 0 2 2 2 1 TIP49 C-terminus AAA_5 PF07728.9 CAM65950.1 - 4.9e-05 23.0 0.0 0.0066 16.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 CAM65950.1 - 9.2e-05 22.5 0.0 0.028 14.5 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.1 CAM65950.1 - 0.0009 18.8 0.3 0.14 11.7 0.1 2.9 3 0 0 3 3 2 1 AAA domain ABC_tran PF00005.22 CAM65950.1 - 0.0012 19.1 0.0 0.079 13.2 0.0 2.7 2 0 0 2 2 2 1 ABC transporter Torsin PF06309.6 CAM65950.1 - 0.0013 18.6 0.1 0.095 12.5 0.1 2.6 2 0 0 2 2 2 1 Torsin NACHT PF05729.7 CAM65950.1 - 0.0016 18.1 0.1 0.046 13.3 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Sigma54_activat PF00158.21 CAM65950.1 - 0.0016 17.9 0.1 0.62 9.5 0.1 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain RuvB_N PF05496.7 CAM65950.1 - 0.0022 17.0 0.0 0.061 12.3 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Bac_DnaA PF00308.13 CAM65950.1 - 0.0022 17.6 0.1 0.0084 15.7 0.0 1.9 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_25 PF13481.1 CAM65950.1 - 0.0024 17.3 0.2 0.41 10.0 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CAM65950.1 - 0.0028 17.9 0.0 1.1 9.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CAM65950.1 - 0.004 16.3 0.3 0.046 12.8 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI PhoH PF02562.11 CAM65950.1 - 0.0059 15.8 1.8 0.085 12.0 0.0 2.9 2 1 1 3 3 3 1 PhoH-like protein AAA_2 PF07724.9 CAM65950.1 - 0.012 15.5 0.0 0.081 12.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Arch_ATPase PF01637.13 CAM65950.1 - 0.013 15.2 0.0 3.4 7.2 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase APS_kinase PF01583.15 CAM65950.1 - 0.02 14.5 0.1 0.32 10.6 0.0 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF258 PF03193.11 CAM65950.1 - 0.027 13.6 0.1 0.15 11.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 CAM65950.1 - 0.036 13.5 4.8 3.2 7.1 0.1 3.8 2 2 2 4 4 4 0 AAA-like domain Sigma54_activ_2 PF14532.1 CAM65950.1 - 0.037 14.0 0.0 0.2 11.7 0.0 2.3 2 0 0 2 2 1 0 Sigma-54 interaction domain SRP54 PF00448.17 CAM65950.1 - 0.048 13.0 0.2 0.29 10.5 0.0 2.3 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain AAA_28 PF13521.1 CAM65950.1 - 0.064 13.2 0.1 1.1 9.2 0.0 2.7 2 1 0 2 2 2 0 AAA domain ResIII PF04851.10 CAM65950.1 - 0.069 12.9 0.0 0.42 10.4 0.1 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit MobB PF03205.9 CAM65950.1 - 0.071 12.8 0.0 0.26 10.9 0.0 2.0 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B KaiC PF06745.8 CAM65950.1 - 0.071 12.2 0.2 3.5 6.6 0.0 2.4 2 0 0 2 2 2 0 KaiC AAA_23 PF13476.1 CAM65950.1 - 0.1 12.8 0.0 1.6 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CAM65950.1 - 0.1 12.1 1.6 6.2 6.4 0.2 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain NB-ARC PF00931.17 CAM65950.1 - 0.11 11.3 0.0 0.27 10.0 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain Guanylate_kin PF00625.16 CAM65950.1 - 0.11 11.8 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Guanylate kinase DAP3 PF10236.4 CAM65950.1 - 0.18 10.7 0.0 0.65 8.8 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 PIF1 PF05970.9 CAM65950.1 - 0.28 10.0 0.1 2.1 7.2 0.1 2.0 2 0 0 2 2 2 0 PIF1-like helicase UPF0079 PF02367.12 CAM65950.1 - 0.48 10.0 1.7 0.55 9.8 0.2 1.7 2 0 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_12 PF13087.1 CAM65952.1 - 3.3e-50 170.2 0.0 5.3e-50 169.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CAM65952.1 - 2.8e-36 125.2 0.0 1e-35 123.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CAM65952.1 - 5.3e-05 22.8 0.3 5.3e-05 22.8 0.2 3.9 4 0 0 4 4 4 1 Part of AAA domain AAA_22 PF13401.1 CAM65952.1 - 0.0026 17.8 0.0 0.025 14.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.9 CAM65952.1 - 0.0028 17.2 0.0 0.12 11.9 0.0 2.9 2 0 0 2 2 2 1 Helicase ResIII PF04851.10 CAM65952.1 - 0.26 11.1 0.0 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 CAM65952.1 - 0.61 9.3 1.5 2.4 7.3 0.0 2.5 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain MSP1_C PF07462.6 CAM65952.1 - 3.9 5.7 1.1 11 4.2 0.8 1.7 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus NapB PF03892.9 CAM65953.1 - 0.11 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Nitrate reductase cytochrome c-type subunit (NapB) Bromodomain PF00439.20 CAM65954.1 - 4.3e-21 74.6 0.0 4.4e-10 39.3 0.0 2.3 2 0 0 2 2 2 2 Bromodomain Mito_carr PF00153.22 CAM65955.1 - 1.7e-44 149.4 7.4 5.7e-17 61.2 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein DZR PF12773.2 CAM65956.1 - 0.0034 17.1 2.3 0.27 11.0 0.0 3.2 2 1 0 2 2 2 1 Double zinc ribbon HypA PF01155.14 CAM65956.1 - 0.013 15.2 0.3 0.51 10.0 0.0 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-FPG_IleRS PF06827.9 CAM65956.1 - 0.087 12.4 0.7 16 5.2 0.1 2.9 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-DNL PF05180.7 CAM65956.1 - 0.14 11.8 0.5 24 4.7 0.4 2.9 2 1 0 2 2 2 0 DNL zinc finger DUF2296 PF10058.4 CAM65956.1 - 0.67 9.7 5.4 10 5.9 0.1 3.7 4 0 0 4 4 4 0 Predicted integral membrane metal-binding protein (DUF2296) L-fibroin PF05849.6 CAM65956.1 - 1.6 8.0 6.4 3.6 6.8 0.6 2.1 2 0 0 2 2 2 0 Fibroin light chain (L-fibroin) Zn_Tnp_IS1595 PF12760.2 CAM65956.1 - 6.3 6.6 10.6 25 4.7 0.2 3.9 4 0 0 4 4 4 0 Transposase zinc-ribbon domain Kelch_4 PF13418.1 CAM65957.1 - 2.3e-12 46.4 0.7 0.096 12.4 0.0 6.1 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 CAM65957.1 - 1.3e-05 24.9 9.8 0.28 11.1 0.0 5.8 5 1 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 CAM65957.1 - 0.00078 19.1 0.9 11 5.9 0.0 5.0 5 0 0 5 5 5 1 Kelch motif Kelch_3 PF13415.1 CAM65957.1 - 0.036 14.2 15.6 11 6.3 0.0 6.3 8 0 0 8 8 8 0 Galactose oxidase, central domain Peptidase_C97 PF05903.9 CAM65958.1 - 2.4e-26 92.3 0.1 2.4e-25 89.0 0.0 1.9 1 1 1 2 2 2 1 PPPDE putative peptidase domain LRAT PF04970.8 CAM65958.1 - 0.03 14.2 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Glyoxalase_4 PF13669.1 CAM65958.1 - 0.049 13.6 0.1 0.095 12.7 0.1 1.6 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Mis14 PF08641.7 CAM65958.1 - 0.21 11.6 0.6 0.29 11.2 0.0 1.5 2 0 0 2 2 2 0 Kinetochore protein Mis14 like Peptidase_C97 PF05903.9 CAM65959.1 - 1.8e-22 79.7 0.0 2.4e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain Flagellar_rod PF05149.7 CAM65961.1 - 1.3e-100 336.2 23.8 1.3e-100 336.2 16.5 1.8 3 0 0 3 3 3 1 Paraflagellar rod protein Glutaredoxin2_C PF04399.8 CAM65961.1 - 0.036 13.6 7.3 0.032 13.8 0.9 2.9 2 1 0 2 2 2 0 Glutaredoxin 2, C terminal domain THUMP PF02926.12 CAM65961.1 - 0.059 13.2 2.1 7.9 6.3 0.0 2.9 2 1 0 2 2 2 0 THUMP domain Aminotran_4 PF01063.14 CAM65961.1 - 0.71 9.2 3.9 0.59 9.5 0.1 2.4 3 0 0 3 3 3 0 Aminotransferase class IV Tweety PF04906.8 CAM65961.1 - 0.94 7.8 5.0 1.1 7.5 0.8 2.4 2 0 0 2 2 2 0 Tweety Peptidase_C6 PF00851.13 CAM65961.1 - 2 6.9 13.1 9.1 4.7 0.1 2.3 1 1 0 2 2 2 0 Helper component proteinase Histone PF00125.19 CAM65963.1 - 2.9e-16 59.3 1.2 3.8e-16 58.9 0.8 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CAM65963.1 - 0.0025 17.8 0.3 0.0048 16.9 0.2 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DNA_photolyase PF00875.13 CAM65963.1 - 0.011 15.4 0.0 0.013 15.2 0.0 1.0 1 0 0 1 1 1 0 DNA photolyase IpaB_EvcA PF03278.8 CAM65963.1 - 0.059 12.6 0.1 0.073 12.2 0.0 1.1 1 0 0 1 1 1 0 IpaB/EvcA family TPR_MLP1_2 PF07926.7 CAM65966.1 - 0.032 13.9 0.4 0.055 13.2 0.3 1.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein F-box PF00646.28 CAM65968.1 - 0.077 12.6 0.0 0.25 11.0 0.0 1.8 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.2 CAM65968.1 - 0.55 9.9 4.1 0.47 10.2 0.2 2.8 2 1 1 3 3 3 0 F-box-like Glyco_hydro_47 PF01532.15 CAM65969.1 - 1.3e-05 24.0 0.0 2.7e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 SET PF00856.23 CAM65970.1 - 2.8e-09 37.4 0.0 1.3e-07 32.0 0.0 2.6 1 1 0 1 1 1 1 SET domain Trigger_C PF05698.9 CAM65971.1 - 8.6e-05 22.4 3.2 0.00021 21.2 2.2 1.9 1 1 1 2 2 2 1 Bacterial trigger factor protein (TF) C-terminus CENP-N PF05238.8 CAM65971.1 - 0.00074 18.6 4.4 0.00086 18.4 3.1 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like SurA_N PF09312.6 CAM65971.1 - 0.016 15.0 1.4 0.027 14.3 0.8 1.5 1 1 0 1 1 1 0 SurA N-terminal domain DUF1318 PF07027.7 CAM65971.1 - 0.021 15.0 0.8 0.021 15.0 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1318) NDUF_B8 PF05821.6 CAM65971.1 - 0.034 13.7 0.2 0.041 13.5 0.1 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) DUF1128 PF06569.6 CAM65971.1 - 0.14 11.8 2.8 4.1 7.1 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1128) DUF4168 PF13767.1 CAM65971.1 - 0.25 12.0 4.0 0.56 10.8 2.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4168) Tho2 PF11262.3 CAM65971.1 - 0.39 9.7 2.9 0.56 9.1 2.0 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF1664 PF07889.7 CAM65971.1 - 0.39 10.5 5.6 0.58 9.9 2.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) GAS PF13851.1 CAM65971.1 - 0.59 9.2 12.5 0.025 13.7 4.8 1.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding UBN2 PF14223.1 CAM65971.1 - 0.87 9.3 6.8 0.61 9.8 1.8 2.5 1 1 2 3 3 3 0 gag-polypeptide of LTR copia-type DUF3812 PF12757.2 CAM65971.1 - 1 9.3 14.7 2.2e+02 1.8 10.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3812) Med8 PF10232.4 CAM65971.1 - 1.3 8.4 5.8 1.6 8.2 4.0 1.2 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 L31 PF09784.4 CAM65971.1 - 1.7 8.7 5.8 0.56 10.3 2.0 1.7 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L31 DUF4407 PF14362.1 CAM65971.1 - 2.2 7.1 8.5 2.8 6.8 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.14 CAM65971.1 - 3.3 5.4 5.7 3.7 5.2 3.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HSCB_C PF07743.8 CAM65971.1 - 3.9 8.0 9.2 15 6.1 3.9 3.0 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain DivIC PF04977.10 CAM65971.1 - 8 6.0 10.1 0.68 9.4 1.9 2.4 3 0 0 3 3 3 0 Septum formation initiator Coq4 PF05019.8 CAM65972.1 - 1.1e-55 187.9 0.0 1.3e-55 187.7 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 DnaJ PF00226.26 CAM65973.1 - 1.6e-12 46.9 0.1 3.2e-12 45.9 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain GcrA PF07750.6 CAM65973.1 - 0.012 15.8 0.0 0.032 14.4 0.0 1.7 1 0 0 1 1 1 0 GcrA cell cycle regulator Rhodanese PF00581.15 CAM65974.1 - 0.00011 22.4 0.0 0.00015 22.0 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain FoP_duplication PF13865.1 CAM65974.1 - 0.14 12.6 0.3 0.14 12.6 0.2 1.6 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Rhodanese PF00581.15 CAM65975.1 - 5.6e-15 55.6 0.0 7.4e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain HTH_18 PF12833.2 CAM65975.1 - 0.14 12.2 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Rhodanese PF00581.15 CAM65976.1 - 8.1e-19 68.0 0.0 9.3e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Tet_JBP PF12851.2 CAM65977.1 - 1.1e-22 80.1 0.0 2e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Cyt-b5 PF00173.23 CAM65978.1 - 3.5e-19 68.3 0.3 4.8e-19 67.9 0.2 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cyt-b5 PF00173.23 CAM65979.1 - 1.5e-13 50.3 0.0 2.6e-13 49.5 0.0 1.4 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Laminin_G_3 PF13385.1 CAM65981.1 - 4.6e-06 26.9 0.0 0.031 14.5 0.0 2.4 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.19 CAM65981.1 - 0.0013 18.7 0.0 0.27 11.2 0.0 2.7 2 0 0 2 2 2 2 Laminin G domain IQ PF00612.22 CAM65981.1 - 0.023 14.3 0.0 0.083 12.5 0.0 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif CPT PF07931.7 CAM65981.1 - 0.05 13.2 0.7 0.13 11.8 0.5 1.7 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein LRR_6 PF13516.1 CAM65982.1 - 2.6e-15 54.7 1.2 0.0031 17.4 0.1 7.1 7 0 0 7 7 7 4 Leucine Rich repeat EF-hand_6 PF13405.1 CAM65983.1 - 0.00076 19.1 0.2 0.31 11.0 0.0 3.4 2 1 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 CAM65983.1 - 0.0054 16.8 0.0 0.013 15.6 0.0 1.7 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CAM65983.1 - 0.032 13.5 0.0 0.23 10.8 0.0 2.4 3 0 0 3 3 3 0 EF hand RIIa PF02197.12 CAM65983.1 - 0.041 13.3 0.0 0.084 12.3 0.0 1.5 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit TMF_DNA_bd PF12329.3 CAM65984.1 - 0.0069 16.1 5.3 0.0069 16.1 3.7 9.3 5 3 2 8 8 8 2 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.4 CAM65984.1 - 0.01 15.6 18.8 0.01 15.6 13.0 7.0 2 2 2 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.3 CAM65984.1 - 0.99 9.2 90.7 0.043 13.7 11.1 8.0 2 2 4 7 7 7 0 Afadin- and alpha -actinin-Binding CCDC155 PF14662.1 CAM65984.1 - 1.1 8.8 89.4 0.89 9.1 14.7 5.5 2 2 3 5 5 5 0 Coiled-coil region of CCDC155 PHO4 PF01384.15 CAM65986.2 - 2.7e-108 361.5 15.6 4.6e-108 360.7 10.8 1.4 1 1 0 1 1 1 1 Phosphate transporter family Gryzun PF07919.7 CAM66018.1 - 1.1e-51 175.8 0.0 1.4e-51 175.4 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi MMS19_N PF14500.1 CAM66019.1 - 7.3e-33 113.9 3.0 9.1e-33 113.6 0.8 2.1 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II Kdo PF06293.9 CAM66019.1 - 0.058 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Thymidylate_kin PF02223.12 CAM66020.1 - 1.7e-15 56.8 0.0 5.8e-15 55.1 0.0 1.8 1 1 0 1 1 1 1 Thymidylate kinase Ribosomal_L35Ae PF01247.13 CAM66021.1 - 3.2e-35 119.7 1.6 4.6e-35 119.2 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 CAM66021.1 - 7.2e-05 22.6 0.4 0.088 12.7 0.0 2.4 2 1 0 2 2 2 2 RimM N-terminal domain adh_short PF00106.20 CAM66023.1 - 5.6e-17 62.1 0.0 1.4e-16 60.9 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 CAM66023.1 - 7.6e-07 28.8 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 CAM66023.1 - 1.2e-06 28.2 0.0 2.3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CAM66023.1 - 0.00053 19.8 0.0 0.00085 19.1 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CAM66023.1 - 0.037 14.0 0.0 0.097 12.6 0.0 1.7 2 0 0 2 2 2 0 NADH(P)-binding Glyco_transf_28 PF03033.15 CAM66023.1 - 0.057 13.1 0.1 2.7 7.7 0.0 3.0 3 0 0 3 3 3 0 Glycosyltransferase family 28 N-terminal domain SRP40_C PF05022.7 CAM66024.1 - 8.6e-07 29.3 0.3 1.6e-06 28.4 0.2 1.5 1 0 0 1 1 1 1 SRP40, C-terminal domain WD40 PF00400.27 CAM66025.1 - 5.4e-47 156.0 27.2 2.1e-10 40.0 0.7 7.7 7 1 0 7 7 7 7 WD domain, G-beta repeat PSP1 PF04468.7 CAM66026.1 - 4.4e-25 87.4 0.1 6.5e-25 86.9 0.1 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Gag_p6 PF08705.6 CAM66027.1 - 0.091 12.8 0.2 0.091 12.8 0.1 2.4 3 0 0 3 3 3 0 Gag protein p6 Phage_GP20 PF06810.6 CAM66027.1 - 0.13 11.7 4.4 0.26 10.7 3.1 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 BLOC1_2 PF10046.4 CAM66027.1 - 0.15 12.2 8.4 2 8.6 2.1 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlxA PF14282.1 CAM66027.1 - 0.21 11.5 11.6 0.65 9.9 3.5 2.7 1 1 0 2 2 2 0 FlxA-like protein CCDC155 PF14662.1 CAM66027.1 - 0.44 10.1 17.9 0.016 14.8 7.7 1.8 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 AAA_13 PF13166.1 CAM66027.1 - 0.66 8.3 6.5 0.95 7.8 4.5 1.2 1 0 0 1 1 1 0 AAA domain NPV_P10 PF05531.7 CAM66027.1 - 1.3 9.3 6.7 8.5 6.7 0.5 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein APG6 PF04111.7 CAM66027.1 - 1.7 7.6 6.7 3.4 6.6 4.6 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Spectrin PF00435.16 CAM66027.1 - 2.3 8.5 15.6 3.8 7.8 4.7 3.2 2 1 1 3 3 3 0 Spectrin repeat DEAD PF00270.24 CAM66028.1 - 9.5e-18 64.2 0.2 2e-14 53.4 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM66028.1 - 1.6e-11 43.9 0.2 5.1e-11 42.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 CAM66028.1 - 1.3e-05 23.7 0.0 0.045 12.1 0.0 3.4 4 0 0 4 4 4 3 Protein of unknown function (DUF1253) DUF2046 PF09755.4 CAM66030.1 - 0.0039 16.1 17.8 0.0039 16.1 12.3 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) Ribosomal_S15 PF00312.17 CAM66030.1 - 0.028 14.1 5.1 0.068 12.9 3.5 1.7 1 0 0 1 1 1 0 Ribosomal protein S15 APG6 PF04111.7 CAM66030.1 - 0.65 8.9 36.5 0.16 10.9 13.3 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 Spc7 PF08317.6 CAM66030.1 - 1.4 7.5 30.4 0.17 10.5 12.9 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein MipZ PF09140.6 CAM66030.1 - 4.1 6.4 9.3 0.14 11.2 1.1 2.2 2 1 0 2 2 2 0 ATPase MipZ ASD2 PF08687.6 CAM66030.1 - 5.3 6.2 29.2 2.1 7.5 12.5 2.9 2 1 0 2 2 2 0 Apx/Shroom domain ASD2 V_ATPase_I PF01496.14 CAM66030.1 - 5.6 4.6 16.9 0.83 7.4 6.1 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF3596 PF12167.3 CAM66030.1 - 7.3 6.2 7.4 1.3 8.5 0.7 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF3596) VIT1 PF01988.14 CAM66030.1 - 7.7 5.9 13.1 0.39 10.1 2.0 2.3 2 0 0 2 2 2 0 VIT family NPV_P10 PF05531.7 CAM66030.1 - 8.3 6.7 15.0 2.7 8.3 3.9 3.6 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1759 PF03564.10 CAM66030.1 - 8.8 6.1 18.0 2.1 8.1 1.5 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF1759) AAA_13 PF13166.1 CAM66030.1 - 9 4.6 23.7 3.5 5.9 9.3 2.1 2 0 0 2 2 2 0 AAA domain Tropomyosin_1 PF12718.2 CAM66030.1 - 9.9 6.0 44.1 0.23 11.3 6.5 3.2 2 1 0 3 3 3 0 Tropomyosin like GDA1_CD39 PF01150.12 CAM66031.1 - 1.2e-59 201.9 0.0 7e-59 199.4 0.0 1.9 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 CAM66031.1 - 0.019 14.2 0.0 0.042 13.0 0.0 1.6 1 0 0 1 1 1 0 Ppx/GppA phosphatase family LRR_4 PF12799.2 CAM66032.1 - 6.6e-18 63.9 12.4 5.1e-07 29.1 1.1 3.2 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM66032.1 - 5e-11 42.1 11.9 1.3e-06 28.0 5.9 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 CAM66032.1 - 1.3e-08 33.6 12.9 0.91 9.7 0.6 6.2 7 0 0 7 7 7 4 Leucine Rich Repeat LRR_7 PF13504.1 CAM66032.1 - 1.5e-06 27.3 11.8 2.3 8.8 0.2 5.6 5 0 0 5 5 5 3 Leucine rich repeat LRR_6 PF13516.1 CAM66032.1 - 0.0013 18.6 13.4 6.7 7.1 0.2 5.3 5 0 0 5 5 5 2 Leucine Rich repeat PDZ_2 PF13180.1 CAM66034.1 - 4.7e-05 23.1 0.0 8.8e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 CAM66034.1 - 0.0001 22.4 0.0 0.00021 21.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) MORN PF02493.15 CAM66035.1 - 3.8e-19 67.2 15.6 2.1e-05 23.9 0.7 4.6 4 0 0 4 4 4 4 MORN repeat Pkinase PF00069.20 CAM66036.1 - 1.3e-58 198.1 0.0 1.7e-58 197.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM66036.1 - 1.3e-27 96.5 0.0 2.3e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CAM66036.1 - 5.4e-06 25.6 0.7 1.1e-05 24.6 0.5 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CAM66036.1 - 0.00054 19.7 1.1 0.00054 19.7 0.8 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CAM66036.1 - 0.025 13.9 0.8 0.17 11.2 0.3 2.2 2 0 0 2 2 2 0 RIO1 family Choline_kinase PF01633.15 CAM66036.1 - 0.093 12.2 0.2 0.2 11.1 0.2 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Nop PF01798.13 CAM66037.1 - 8.5e-56 187.4 0.2 1.5e-55 186.6 0.1 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 CAM66037.1 - 3.3e-22 78.0 0.0 6.9e-22 77.0 0.0 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 CAM66037.1 - 1.3e-20 73.2 0.0 3e-20 72.1 0.0 1.7 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Amastin PF07344.6 CAM66040.1 - 1.7e-40 138.1 21.9 4.5e-25 88.0 3.8 2.3 2 0 0 2 2 2 2 Amastin surface glycoprotein Claudin_2 PF13903.1 CAM66040.1 - 0.44 10.2 33.4 0.2 11.3 6.3 3.6 2 1 2 4 4 4 0 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 CAM66041.1 - 4.9e-62 208.1 15.4 3.4e-36 124.1 4.2 2.1 2 0 0 2 2 2 2 Amastin surface glycoprotein MNSV_P7B PF06692.6 CAM66041.1 - 5.6 6.8 6.6 1.6 8.6 0.1 3.1 3 0 0 3 3 3 0 Melon necrotic spot virus P7B protein Pterin_4a PF01329.14 CAM66043.1 - 7.3e-10 38.4 0.0 2.4e-08 33.5 0.0 2.3 1 1 1 2 2 2 1 Pterin 4 alpha carbinolamine dehydratase HrpB_C PF08482.5 CAM66043.1 - 0.1 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 ATP-dependent helicase C-terminal COPI_assoc PF08507.5 CAM66044.1 - 8.5e-07 28.7 18.9 1.1e-06 28.3 13.1 1.1 1 0 0 1 1 1 1 COPI associated protein RNase_T PF00929.19 CAM66045.1 - 6.3e-18 65.5 0.0 1e-17 64.9 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Iso_dh PF00180.15 CAM66047.1 - 8.5e-73 245.2 0.0 9.8e-73 245.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ead_Ea22 PF13935.1 CAM66048.1 - 0.06 13.6 6.0 0.17 12.2 4.1 1.8 1 0 0 1 1 1 0 Ead/Ea22-like protein V_ATPase_I PF01496.14 CAM66048.1 - 0.21 9.4 4.4 0.29 8.9 3.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3584 PF12128.3 CAM66048.1 - 0.43 7.8 14.2 0.6 7.3 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Atg14 PF10186.4 CAM66048.1 - 0.86 8.4 9.6 1.5 7.6 6.6 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Spc24 PF08286.6 CAM66048.1 - 2.1 8.0 7.8 3.5 7.3 4.9 1.7 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 SlyX PF04102.7 CAM66048.1 - 2.2 8.6 17.5 0.15 12.4 5.2 3.4 4 0 0 4 4 4 0 SlyX DASH_Spc34 PF08657.5 CAM66048.1 - 2.5 7.7 10.5 1.6 8.2 5.2 2.0 1 1 1 2 2 2 0 DASH complex subunit Spc34 Mnd1 PF03962.10 CAM66048.1 - 2.8 7.5 11.0 5 6.7 7.6 1.3 1 0 0 1 1 1 0 Mnd1 family IncA PF04156.9 CAM66048.1 - 3.8 7.0 12.4 9.6 5.7 8.6 1.7 1 1 0 1 1 1 0 IncA protein Sugarporin_N PF11471.3 CAM66048.1 - 9.6 5.9 9.7 9.9 5.9 4.6 2.3 1 1 1 2 2 2 0 Maltoporin periplasmic N-terminal extension Sec23_trunk PF04811.10 CAM66049.1 - 9.3e-41 139.7 0.0 1.4e-20 73.6 0.0 2.2 1 1 1 2 2 2 2 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CAM66049.1 - 1.5e-25 88.5 0.0 3.9e-25 87.2 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 CAM66049.1 - 1.1e-19 70.7 0.0 2.1e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 CAM66049.1 - 8e-07 28.6 0.0 1.6e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.10 CAM66049.1 - 0.015 14.8 8.3 0.032 13.7 5.8 1.6 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger ThiC PF01964.13 CAM66049.1 - 0.083 11.3 4.0 0.2 10.1 0.0 2.1 2 0 0 2 2 2 0 ThiC family Abhydrolase_1 PF00561.15 CAM66050.2 - 8.9e-05 22.1 0.0 0.00032 20.3 0.0 1.9 1 0 0 1 1 1 1 alpha/beta hydrolase fold BT1 PF03092.11 CAM66052.1 - 1.5e-151 504.9 9.2 1.9e-151 504.7 6.4 1.1 1 0 0 1 1 1 1 BT1 family BT1 PF03092.11 CAM66053.1 - 3.9e-201 668.4 2.1 4.4e-201 668.2 1.5 1.0 1 0 0 1 1 1 1 BT1 family BT1 PF03092.11 CAM66054.1 - 1.9e-200 666.1 4.5 2.2e-200 665.9 3.1 1.0 1 0 0 1 1 1 1 BT1 family BT1 PF03092.11 CAM66055.2 - 8.4e-198 657.4 4.6 9.6e-198 657.2 3.2 1.0 1 0 0 1 1 1 1 BT1 family BT1 PF03092.11 CAM66056.1 - 6.8e-197 654.4 3.6 7.8e-197 654.2 2.5 1.0 1 0 0 1 1 1 1 BT1 family Dak1 PF02733.12 CAM66057.1 - 1.6e-85 286.5 1.0 1.6e-85 286.5 0.7 1.7 2 0 0 2 2 2 1 Dak1 domain Dak2 PF02734.12 CAM66057.1 - 3.2e-36 124.6 4.3 3.2e-36 124.6 3.0 1.8 2 0 0 2 2 2 1 DAK2 domain DUF936 PF06075.7 CAM66058.1 - 0.032 13.1 0.4 0.07 12.0 0.1 1.7 1 1 1 2 2 2 0 Plant protein of unknown function (DUF936) zf-C3HC4_3 PF13920.1 CAM66059.1 - 1.4e-08 34.2 11.4 1.4e-08 34.2 7.9 1.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAM66059.1 - 0.13 12.0 11.9 0.3 10.8 8.3 1.6 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CAM66059.1 - 0.19 11.8 11.3 0.63 10.1 8.0 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CAM66060.1 - 7.4e-10 38.3 11.9 1.2e-09 37.6 8.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAM66060.1 - 0.022 14.4 12.3 0.048 13.3 8.5 1.6 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CAM66060.1 - 0.025 14.5 12.9 0.057 13.4 8.9 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) 4F5 PF04419.9 CAM66061.1 - 2.1e-09 37.9 8.4 3.3e-09 37.3 5.8 1.3 1 0 0 1 1 1 1 4F5 protein family zf-met2 PF12907.2 CAM66061.1 - 1.5e-07 31.2 0.8 1.5e-07 31.2 0.5 1.7 2 0 0 2 2 2 1 Zinc-binding zf-C2H2_4 PF13894.1 CAM66061.1 - 0.0068 16.6 1.0 0.052 13.9 0.2 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CAM66061.1 - 0.024 14.9 1.3 0.09 13.1 0.2 2.2 2 1 0 2 2 2 0 Zinc-finger double domain zf-H2C2_5 PF13909.1 CAM66061.1 - 1.8 8.9 5.3 0.82 10.0 0.4 2.4 2 1 0 2 2 2 0 C2H2-type zinc-finger domain BT1 PF03092.11 CAM66062.1 - 5.8e-197 654.6 4.3 6.6e-197 654.4 3.0 1.0 1 0 0 1 1 1 1 BT1 family BT1 PF03092.11 CAM66063.1 - 2.4e-199 662.5 5.2 2.9e-199 662.2 3.6 1.1 1 0 0 1 1 1 1 BT1 family MFS_1 PF07690.11 CAM66063.1 - 5.5 5.5 50.8 0.16 10.6 8.8 4.3 2 2 0 3 3 3 0 Major Facilitator Superfamily Peptidase_M8 PF01457.11 CAM66064.2 - 1.1e-253 842.3 2.0 1.3e-253 842.1 1.4 1.0 1 0 0 1 1 1 1 Leishmanolysin DUF1025 PF06262.6 CAM66064.2 - 0.0091 15.7 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 Possibl zinc metallo-peptidase Peptidase_M8 PF01457.11 CAM66066.2 - 6.4e-262 869.4 0.8 7.3e-262 869.2 0.6 1.0 1 0 0 1 1 1 1 Leishmanolysin DUF1025 PF06262.6 CAM66066.2 - 0.14 11.9 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase Peptidase_M8 PF01457.11 CAM66067.1 - 3.8e-260 863.6 3.4 4.4e-260 863.4 2.4 1.0 1 0 0 1 1 1 1 Leishmanolysin DUF1025 PF06262.6 CAM66067.1 - 0.084 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase Peptidase_M8 PF01457.11 CAM66068.2 - 9e-258 855.8 3.5 1.1e-257 855.5 2.4 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M57 PF12388.3 CAM66068.2 - 0.07 12.4 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase DUF1025 PF06262.6 CAM66068.2 - 0.078 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase Pkinase PF00069.20 CAM66069.1 - 3.7e-65 219.6 0.0 4.3e-65 219.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM66069.1 - 4.6e-28 97.9 0.0 2.9e-27 95.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM66069.1 - 0.0056 15.6 0.0 0.0086 15.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CAM66069.1 - 0.01 14.9 0.0 0.017 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sarcoglycan_2 PF05510.8 CAM66070.2 - 0.56 8.4 0.0 1.2 7.3 0.0 1.4 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon Baculo_11_kDa PF06143.6 CAM66070.2 - 0.57 9.5 2.4 1.3 8.4 1.6 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family NAD_Gly3P_dh_C PF07479.9 CAM66071.1 - 1.7e-49 167.3 0.8 3e-49 166.5 0.6 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 CAM66071.1 - 3.2e-48 163.4 0.1 4.8e-48 162.8 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 CAM66071.1 - 9.5e-06 25.1 0.0 1.8e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.12 CAM66071.1 - 0.00094 19.5 0.0 0.0024 18.2 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF1188 PF06690.6 CAM66071.1 - 0.0013 17.9 0.0 0.0027 16.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1188) NAD_binding_2 PF03446.10 CAM66071.1 - 0.0039 17.0 0.0 0.02 14.7 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 CAM66071.1 - 0.033 13.8 0.1 0.086 12.4 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA_C PF08546.6 CAM66071.1 - 0.11 12.4 0.2 0.28 11.1 0.2 1.9 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal Pyr_redox PF00070.22 CAM66071.1 - 0.17 12.2 1.0 6.1 7.3 0.1 3.4 3 1 1 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase DUF2347 PF09804.4 CAM66073.1 - 0.17 11.1 0.0 0.17 11.1 0.0 4.6 4 1 1 5 5 5 0 Uncharacterized conserved protein (DUF2347) Amidinotransf PF02274.12 CAM66075.1 - 0.0023 17.0 0.0 0.0037 16.3 0.0 1.3 1 0 0 1 1 1 1 Amidinotransferase ADH_zinc_N PF00107.21 CAM66076.1 - 4.6e-16 58.5 0.0 8.3e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CAM66076.1 - 1.8e-09 37.2 0.1 9.7e-09 34.9 0.1 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 CAM66076.1 - 5.5e-08 33.7 0.0 1.1e-07 32.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Cupin_2 PF07883.6 CAM66076.1 - 0.059 12.8 0.3 0.15 11.6 0.1 1.7 2 0 0 2 2 2 0 Cupin domain ADH_zinc_N PF00107.21 CAM66077.1 - 1.2e-17 63.6 0.0 2.2e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CAM66077.1 - 1.1e-10 42.5 0.1 1.1e-10 42.5 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CAM66077.1 - 5.6e-06 26.0 0.0 1.8e-05 24.4 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CAF1A PF12253.3 CAM66078.1 - 1.1e-07 31.8 1.7 1.1e-07 31.8 1.2 3.0 2 0 0 2 2 2 1 Chromatin assembly factor 1 subunit A Ycf1 PF05758.7 CAM66078.1 - 1.7 6.2 8.6 3.5 5.2 5.9 1.4 1 0 0 1 1 1 0 Ycf1 LTXXQ PF07813.7 CAM66079.1 - 0.12 12.8 3.5 0.16 12.4 0.2 2.4 3 0 0 3 3 3 0 LTXXQ motif family protein ABC1 PF03109.11 CAM66080.1 - 2.5e-22 79.0 0.0 1.9e-21 76.2 0.0 2.1 2 0 0 2 2 2 1 ABC1 family Pkinase PF00069.20 CAM66080.1 - 0.075 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain APH PF01636.18 CAM66080.1 - 0.16 11.7 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Endonuclease_NS PF01223.18 CAM66081.1 - 2.2e-47 161.3 0.0 4.2e-47 160.4 0.0 1.5 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.1 CAM66081.1 - 0.06 13.3 0.1 0.18 11.8 0.1 1.7 1 1 0 1 1 1 0 DNA/RNA non-specific endonuclease AF-4 PF05110.8 CAM66083.1 - 2.1 6.1 17.4 2.9 5.6 12.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein zf-CCCH PF00642.19 CAM66084.1 - 0.047 13.3 2.6 0.078 12.6 1.8 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Mito_fiss_reg PF05308.6 CAM66084.1 - 0.21 10.8 1.0 0.3 10.4 0.7 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator HTH_32 PF13565.1 CAM66085.1 - 0.35 11.7 5.7 0.46 11.3 1.4 2.5 2 0 0 2 2 2 0 Homeodomain-like domain DUF1751 PF08551.5 CAM66087.2 - 0.00031 21.0 0.7 0.002 18.4 0.2 2.2 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) CDV3 PF15359.1 CAM66087.2 - 0.75 9.8 5.6 2.1 8.4 3.5 1.9 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 DUF4175 PF13779.1 CAM66087.2 - 7.8 4.0 12.2 10 3.6 8.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) ADH_zinc_N PF00107.21 CAM66088.1 - 0.039 13.5 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase HEAT PF02985.17 CAM66089.1 - 1.6e-05 24.6 37.4 0.0022 17.9 0.1 9.5 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.1 CAM66089.1 - 0.044 14.0 0.1 0.044 14.0 0.1 9.4 7 2 2 9 9 9 0 HEAT repeats HEAT_EZ PF13513.1 CAM66089.1 - 1.8 9.1 25.7 0.16 12.5 0.3 7.3 6 0 0 6 6 6 0 HEAT-like repeat RRM_1 PF00076.17 CAM66090.1 - 3e-43 145.2 0.9 2e-15 56.1 0.0 6.5 6 1 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM66090.1 - 4.3e-40 135.5 0.1 6.9e-14 51.5 0.0 5.8 6 0 0 6 6 6 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM66090.1 - 1.1e-22 79.6 0.0 1e-07 31.7 0.0 5.3 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CAM66090.1 - 0.022 14.5 0.0 1.6 8.5 0.0 2.9 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 CAM66090.1 - 0.023 14.4 0.2 13 5.6 0.1 3.8 2 1 0 2 2 2 0 Limkain b1 Aa_trans PF01490.13 CAM66091.1 - 9.3e-41 139.6 37.5 1.5e-40 138.9 26.0 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein SPT6_acidic PF14632.1 CAM66091.1 - 0.13 12.4 0.5 0.18 11.9 0.3 1.1 1 0 0 1 1 1 0 Acidic N-terminal SPT6 Aa_trans PF01490.13 CAM66092.1 - 2.3e-40 138.3 37.5 3.7e-40 137.6 26.0 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein SPT6_acidic PF14632.1 CAM66092.1 - 0.13 12.4 0.5 0.18 11.9 0.3 1.1 1 0 0 1 1 1 0 Acidic N-terminal SPT6 dCMP_cyt_deam_1 PF00383.17 CAM66093.1 - 7e-13 48.1 0.2 9.8e-11 41.2 0.1 2.7 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 CAM66093.1 - 0.00014 21.7 1.4 0.3 10.9 0.1 2.3 2 0 0 2 2 2 2 Bd3614-like deaminase DUF3602 PF12223.3 CAM66094.1 - 0.11 12.8 1.1 0.25 11.7 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3602) MTHFR PF02219.12 CAM66096.1 - 0.047 12.7 0.1 1.4 7.9 0.0 2.9 4 0 0 4 4 4 0 Methylenetetrahydrofolate reductase MTHFR PF02219.12 CAM66097.2 - 0.039 13.0 0.1 12 4.9 0.0 3.4 4 0 0 4 4 4 0 Methylenetetrahydrofolate reductase WD40 PF00400.27 CAM66098.1 - 6.5e-84 273.1 17.3 1.2e-10 40.8 0.1 8.1 8 0 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 CAM66098.1 - 1.4e-06 26.7 12.2 0.16 10.0 0.0 5.9 2 1 5 7 7 7 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CAM66098.1 - 0.004 15.9 0.2 2.6 6.6 0.0 2.9 1 1 2 3 3 3 2 Nup133 N terminal like CEP19 PF14933.1 CAM66098.1 - 0.04 14.2 0.0 0.061 13.6 0.0 1.3 1 0 0 1 1 1 0 CEP19-like protein DUF3942 PF13078.1 CAM66098.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3942) TPR_11 PF13414.1 CAM66102.1 - 5.3e-05 22.7 0.9 0.00021 20.8 0.7 2.1 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 CAM66102.1 - 0.00055 19.6 0.8 4.4 7.4 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CAM66102.1 - 0.01 15.7 2.9 0.095 12.6 1.7 2.5 1 1 0 1 1 1 0 Tetratricopeptide repeat DUF2153 PF09921.4 CAM66102.1 - 0.053 13.1 0.1 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) Pkinase PF00069.20 CAM66103.2 - 6.4e-22 77.9 0.0 7.7e-18 64.5 0.0 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAM66103.2 - 4.9e-06 25.8 0.0 5e-05 22.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase A_deaminase PF00962.17 CAM66104.1 - 1.1e-07 31.1 0.9 0.0007 18.6 0.0 3.2 3 0 0 3 3 3 2 Adenosine/AMP deaminase DUF3678 PF12435.3 CAM66104.1 - 0.11 12.1 6.5 0.62 9.6 4.5 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) NTF2 PF02136.15 CAM66105.1 - 1.4e-26 93.1 0.3 1.5e-26 93.0 0.2 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.1 CAM66105.1 - 0.0004 20.5 0.0 0.00048 20.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Lumazine_bd_2 PF12893.2 CAM66105.1 - 0.0016 18.9 0.1 0.002 18.6 0.1 1.4 1 1 0 1 1 1 1 Putative lumazine-binding SnoaL_2 PF12680.2 CAM66105.1 - 0.0089 16.4 0.1 0.011 16.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain Nop16 PF09420.5 CAM66106.1 - 4.6e-27 95.1 4.7 1.2e-26 93.7 3.3 1.6 1 1 0 1 1 1 1 Ribosome biogenesis protein Nop16 YpjP PF14005.1 CAM66106.1 - 0.026 14.2 0.1 0.039 13.7 0.1 1.2 1 0 0 1 1 1 0 YpjP-like protein DUF3435 PF11917.3 CAM66106.1 - 0.029 13.0 0.4 0.035 12.8 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) Glyco_hydro_4C PF11975.3 CAM66106.1 - 0.062 13.0 0.3 0.086 12.6 0.2 1.2 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain EcoR124_C PF12008.3 CAM66106.1 - 0.092 11.9 0.9 1.1 8.4 0.1 2.0 1 1 1 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal Mnd1 PF03962.10 CAM66106.1 - 0.13 11.9 1.2 0.19 11.4 0.8 1.2 1 0 0 1 1 1 0 Mnd1 family Histone PF00125.19 CAM66107.1 - 2.9e-27 94.5 0.6 2.9e-27 94.5 0.4 1.8 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CAM66107.1 - 1.3e-05 25.2 0.0 2.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CAM66107.1 - 2.1e-05 24.4 0.1 2.1e-05 24.4 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CAM66107.1 - 0.0011 18.6 0.1 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 CAM66107.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TMA7 PF09072.5 CAM66107.1 - 0.15 12.5 3.0 0.24 11.8 2.1 1.4 1 0 0 1 1 1 0 Translation machinery associated TMA7 FKBP_C PF00254.23 CAM66109.1 - 1.2e-24 86.0 0.0 1.9e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.13 CAM66109.1 - 0.11 12.5 0.0 0.51 10.3 0.0 1.9 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Ras PF00071.17 CAM66111.1 - 1.5e-59 199.9 0.1 1.8e-59 199.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAM66111.1 - 1.2e-18 67.7 0.0 1.9e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAM66111.1 - 8.7e-15 54.3 0.0 1.1e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CAM66111.1 - 3e-06 26.7 0.0 8.3e-06 25.3 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CAM66111.1 - 6.2e-06 26.1 0.0 1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.1 CAM66111.1 - 0.00048 19.2 0.1 0.00062 18.9 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.5 CAM66111.1 - 0.0011 18.1 0.2 0.0019 17.4 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CAM66111.1 - 0.0019 17.3 0.0 0.0022 17.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 CAM66111.1 - 0.0021 18.1 0.0 0.0035 17.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 CAM66111.1 - 0.0026 16.9 0.1 0.0068 15.6 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 CAM66111.1 - 0.013 14.8 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B Septin PF00735.13 CAM66111.1 - 0.024 13.6 0.1 0.036 13.0 0.1 1.2 1 0 0 1 1 1 0 Septin AAA_5 PF07728.9 CAM66111.1 - 0.045 13.4 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 CAM66111.1 - 0.11 11.9 0.1 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Amidase02_C PF12123.3 CAM66111.1 - 0.12 12.0 0.1 0.36 10.5 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase ABC_tran PF00005.22 CAM66111.1 - 0.15 12.3 0.1 0.2 11.9 0.1 1.5 1 1 0 1 1 1 0 ABC transporter IF-2B PF01008.12 CAM66117.1 - 6.5e-41 140.1 0.0 3.6e-39 134.4 0.0 2.1 2 0 0 2 2 2 2 Initiation factor 2 subunit family PriCT_1 PF08708.6 CAM66118.2 - 0.028 14.2 1.5 9.7 6.0 0.0 3.6 3 0 0 3 3 3 0 Primase C terminal 1 (PriCT-1) Histone PF00125.19 CAM66119.1 - 0.019 15.0 0.7 0.059 13.4 0.0 2.1 2 1 0 2 2 2 0 Core histone H2A/H2B/H3/H4 TMA7 PF09072.5 CAM66119.1 - 0.082 13.3 3.0 0.11 13.0 2.1 1.2 1 0 0 1 1 1 0 Translation machinery associated TMA7 PNP_UDP_1 PF01048.15 CAM66121.1 - 9.4e-43 145.8 0.2 1.2e-42 145.4 0.2 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Mito_carr PF00153.22 CAM66122.2 - 1.6e-24 85.3 0.9 4.7e-09 35.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein NDUF_B12 PF08122.7 CAM66122.2 - 0.044 13.5 0.0 10 5.9 0.0 2.7 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family RRM_1 PF00076.17 CAM66123.1 - 3e-10 39.5 0.0 5.7e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM66123.1 - 7e-10 38.7 0.0 1.4e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM66123.1 - 2.8e-06 27.0 0.5 7.1e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.9 CAM66123.1 - 0.16 10.0 1.1 0.18 9.7 0.8 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1042 PF06294.6 CAM66124.2 - 6.6e-14 51.7 0.0 1.2e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1042) CAMSAP_CH PF11971.3 CAM66124.2 - 0.0067 16.0 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain DnaJ PF00226.26 CAM66125.1 - 2e-08 33.8 0.1 3.9e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain KN_motif PF12075.3 CAM66125.1 - 0.19 11.5 1.9 2.5 7.9 0.1 2.5 2 0 0 2 2 2 0 KN motif DUF1491 PF07372.7 CAM66126.1 - 0.05 13.5 0.3 0.1 12.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1491) IncA PF04156.9 CAM66127.1 - 0.00016 21.3 0.2 0.00016 21.3 0.1 5.3 2 1 3 5 5 5 2 IncA protein MIF4G PF02854.14 CAM66128.1 - 2e-14 53.5 1.3 2.7e-14 53.0 0.4 1.6 2 0 0 2 2 2 1 MIF4G domain DUF4041 PF13250.1 CAM66128.1 - 0.016 14.7 0.0 0.04 13.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4041) Herpes_BLRF2 PF05812.7 CAM66128.1 - 0.024 14.4 1.0 0.058 13.1 0.7 1.6 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein PARP_reg PF02877.9 CAM66128.1 - 0.031 13.9 0.9 1 9.0 0.0 2.6 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase, regulatory domain TetR_C_8 PF14278.1 CAM66128.1 - 0.062 13.6 1.0 17 5.9 0.0 3.7 3 1 0 3 3 3 0 Transcriptional regulator C-terminal region NDK PF00334.14 CAM66129.1 - 0.0007 19.3 0.0 0.0075 16.0 0.0 2.1 2 0 0 2 2 2 1 Nucleoside diphosphate kinase MIG-14_Wnt-bd PF06664.7 CAM66130.1 - 0.055 12.2 2.0 0.064 12.0 0.6 1.4 1 1 0 1 1 1 0 Wnt-binding factor required for Wnt secretion COX15-CtaA PF02628.10 CAM66130.1 - 0.36 9.6 9.1 0.51 9.1 6.3 1.2 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein 7TMR-DISM_7TM PF07695.6 CAM66130.1 - 0.96 9.0 8.0 1.6 8.3 5.6 1.3 1 0 0 1 1 1 0 7TM diverse intracellular signalling ABC2_membrane_2 PF12679.2 CAM66130.1 - 1.7 7.4 12.9 2.4 6.9 8.9 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF4418 PF14387.1 CAM66130.1 - 4.6 6.9 9.2 1 9.0 3.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4418) LsmAD PF06741.8 CAM66132.1 - 1.2e-22 79.7 2.0 2.6e-22 78.6 1.4 1.6 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.1 CAM66132.1 - 7.4e-13 48.2 0.0 1.7e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Ataxin 2 SM domain zf-C3HC4_3 PF13920.1 CAM66135.1 - 5.7e-16 57.9 9.6 1.1e-15 57.0 6.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAM66135.1 - 1.9e-08 34.2 14.0 3.5e-08 33.3 9.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CAM66135.1 - 5e-05 23.0 13.1 0.0001 22.0 9.1 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.1 CAM66135.1 - 0.024 14.1 5.0 0.052 13.0 3.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.1 CAM66135.1 - 0.12 12.1 11.8 0.24 11.1 8.2 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.1 CAM66135.1 - 0.54 9.8 9.0 1 8.9 6.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.9 CAM66135.1 - 1.7 8.1 9.5 4.1 6.9 6.6 1.6 1 0 0 1 1 1 0 P-11 zinc finger Trichoplein PF13868.1 CAM66136.1 - 1.9e-68 230.4 153.4 1.9e-68 230.4 106.3 2.0 2 0 0 2 2 2 1 Tumour suppressor, Mitostatin ThiS PF02597.15 CAM66136.1 - 7 7.1 7.8 3.2 8.2 2.3 2.9 2 0 0 2 2 2 0 ThiS family Ras PF00071.17 CAM66137.1 - 1.8e-54 183.5 0.1 2.2e-54 183.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAM66137.1 - 1.1e-16 61.3 0.0 3.3e-16 59.8 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CAM66137.1 - 3.9e-11 42.4 0.0 5.2e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CAM66137.1 - 2.2e-08 33.7 0.1 4.9e-07 29.3 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CAM66137.1 - 2.8e-06 27.2 0.0 4.2e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CAM66137.1 - 1.4e-05 24.3 0.2 2.1e-05 23.7 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_18 PF13238.1 CAM66137.1 - 0.00056 20.2 0.0 0.0013 19.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CAM66137.1 - 0.00067 19.6 0.0 0.0011 19.0 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 CAM66137.1 - 0.0023 17.1 0.1 0.0099 15.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 CAM66137.1 - 0.0041 16.6 0.0 0.017 14.5 0.0 1.9 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 CAM66137.1 - 0.0071 15.9 0.3 0.56 9.7 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.5 CAM66137.1 - 0.015 14.5 0.0 0.022 13.9 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit IIGP PF05049.8 CAM66137.1 - 0.023 13.5 0.0 0.15 10.8 0.0 2.0 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_17 PF13207.1 CAM66137.1 - 0.024 15.4 0.1 0.035 14.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CAM66137.1 - 0.025 14.8 0.1 0.1 12.9 0.1 2.0 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.1 CAM66137.1 - 0.03 13.8 0.1 0.11 12.0 0.0 1.9 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 CAM66137.1 - 0.047 13.8 0.0 0.18 12.0 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Paramyxo_NS_C PF02725.9 CAM66137.1 - 0.052 13.1 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 Non-structural protein C AAA_22 PF13401.1 CAM66137.1 - 0.065 13.3 0.1 0.16 12.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 CAM66137.1 - 0.078 11.9 0.1 0.17 10.8 0.0 1.5 2 0 0 2 2 2 0 Septin PRK PF00485.13 CAM66137.1 - 0.08 12.4 0.2 0.16 11.5 0.0 1.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.1 CAM66137.1 - 0.1 12.1 0.1 0.58 9.7 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain MobB PF03205.9 CAM66137.1 - 0.11 12.2 0.0 0.38 10.4 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 CAM66137.1 - 0.15 11.8 0.5 2.7 7.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 Ras PF00071.17 CAM66138.1 - 4.3e-45 153.0 0.0 5e-45 152.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAM66138.1 - 4.9e-13 49.6 0.0 8.6e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAM66138.1 - 6.8e-07 28.6 0.0 8.2e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CAM66138.1 - 1e-05 24.7 0.0 1.3e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CAM66138.1 - 1.8e-05 24.2 0.0 0.0009 18.7 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CAM66138.1 - 0.034 14.0 0.0 0.072 13.0 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Nterm_IS4 PF13006.2 CAM66139.1 - 0.03 14.3 0.5 0.11 12.5 0.4 1.9 1 1 0 1 1 1 0 Insertion element 4 transposase N-terminal MerC PF03203.9 CAM66139.1 - 0.11 12.8 2.3 0.22 11.9 1.6 1.5 1 1 0 1 1 1 0 MerC mercury resistance protein DUF4131 PF13567.1 CAM66139.1 - 8.5 5.7 8.2 9.3 5.6 2.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) RIB43A PF05914.7 CAM66140.1 - 2.3e-117 391.8 62.6 2.8e-117 391.5 43.4 1.0 1 0 0 1 1 1 1 RIB43A zf-RanBP PF00641.13 CAM66141.1 - 1.5e-09 36.7 24.0 0.00062 18.8 3.6 3.7 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others DZR PF12773.2 CAM66141.1 - 1.1e-07 31.5 19.2 0.0001 22.0 7.5 2.6 1 1 1 2 2 2 2 Double zinc ribbon zf-RING_3 PF14369.1 CAM66141.1 - 0.12 12.3 0.9 0.12 12.3 0.6 3.5 3 1 0 3 3 3 0 zinc-finger zinc-ribbons_6 PF07191.7 CAM66141.1 - 1.4 8.7 12.1 18 5.2 0.4 3.5 3 0 0 3 3 3 0 zinc-ribbons DUF3279 PF11682.3 CAM66141.1 - 3.8 7.0 18.4 0.64 9.6 0.7 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3279) GSK-3_bind PF05350.7 CAM66141.1 - 5.3 6.4 9.4 21 4.4 6.5 1.8 1 1 0 1 1 1 0 Glycogen synthase kinase-3 binding zf-B_box PF00643.19 CAM66141.1 - 6.3 6.7 8.5 1.5 8.7 0.5 2.9 3 0 0 3 3 3 0 B-box zinc finger zf-ribbon_3 PF13248.1 CAM66141.1 - 8.3 5.7 28.4 0.22 10.7 2.3 3.8 4 0 0 4 4 4 0 zinc-ribbon domain PduL PF06130.7 CAM66143.1 - 0.074 12.8 0.6 3.4 7.5 0.1 2.6 2 0 0 2 2 2 0 Propanediol utilisation protein PduL Atx10homo_assoc PF09759.4 CAM66144.1 - 1e-30 105.4 0.0 1.9e-30 104.5 0.0 1.4 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain zf-CHY PF05495.7 CAM66146.1 - 0.051 13.7 0.2 0.099 12.8 0.1 1.4 1 0 0 1 1 1 0 CHY zinc finger Methyltransf_23 PF13489.1 CAM66147.1 - 3e-26 92.0 0.0 3.9e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CAM66147.1 - 1.5e-05 25.3 0.0 0.00048 20.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAM66147.1 - 6.8e-05 23.2 0.0 0.0009 19.6 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAM66147.1 - 0.0035 16.9 0.0 0.01 15.4 0.0 1.8 1 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 CAM66147.1 - 0.013 14.6 0.0 0.05 12.7 0.0 1.8 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 CAM66147.1 - 0.07 13.7 0.0 0.55 10.8 0.0 2.5 1 1 0 1 1 1 0 Methyltransferase domain c-SKI_SMAD_bind PF08782.5 CAM66147.1 - 0.13 12.4 0.4 0.37 10.9 0.1 1.7 1 1 1 2 2 2 0 c-SKI Smad4 binding domain C1_3 PF07649.7 CAM66147.1 - 0.53 10.3 3.2 3.2 7.8 2.2 2.3 1 1 0 1 1 1 0 C1-like domain DUF1861 PF08950.5 CAM66148.1 - 2.9e-141 469.5 0.3 3.3e-141 469.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) DUF1861 PF08950.5 CAM66149.1 - 9.7e-137 454.7 0.1 1.1e-136 454.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) Phage_hub_GP28 PF11110.3 CAM66149.1 - 0.081 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Baseplate hub distal subunit DUF1861 PF08950.5 CAM66150.1 - 5e-142 472.0 0.1 5.8e-142 471.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) DUF1861 PF08950.5 CAM66151.1 - 2.3e-139 463.3 0.0 2.6e-139 463.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) DUF1861 PF08950.5 CAM66152.1 - 6.3e-141 468.4 0.0 7.2e-141 468.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) DUF1861 PF08950.5 CAM66153.1 - 6.5e-144 478.2 0.0 7.4e-144 478.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) DUF1861 PF08950.5 CAM66154.1 - 3.8e-142 472.4 0.1 4.3e-142 472.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) Qn_am_d_aII PF14930.1 CAM66154.1 - 0.15 12.0 0.2 1.2 9.1 0.0 2.3 1 1 1 2 2 2 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II PHO4 PF01384.15 CAM66155.1 - 2.7e-108 361.5 15.6 4.6e-108 360.7 10.8 1.4 1 1 0 1 1 1 1 Phosphate transporter family BT1 PF03092.11 CAM66156.1 - 1.9e-146 488.2 11.4 2.3e-146 487.9 7.9 1.0 1 0 0 1 1 1 1 BT1 family MFS_1 PF07690.11 CAM66156.1 - 0.011 14.4 42.6 0.035 12.8 5.6 4.0 3 1 1 4 4 4 0 Major Facilitator Superfamily DUF3704 PF12488.3 CAM66156.1 - 0.043 13.4 0.2 0.53 9.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3704) FA_desaturase PF00487.19 CAM66157.1 - 7.9e-28 97.5 25.3 7.9e-28 97.5 17.5 1.7 1 1 1 2 2 2 1 Fatty acid desaturase DUF2530 PF10745.4 CAM66157.1 - 4.6 7.2 7.0 4 7.4 2.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) BetaGal_dom3 PF13363.1 CAM66170.2 - 0.04 13.2 0.1 0.12 11.8 0.1 1.8 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 DUF1140 PF06600.6 CAM66170.2 - 0.34 11.0 0.1 1.1 9.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1140) ATG16 PF08614.6 CAM66173.1 - 0.0013 18.6 8.2 0.0013 18.6 5.7 1.7 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.4 CAM66173.1 - 0.0097 15.7 15.6 0.02 14.7 2.4 2.2 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 CAM66173.1 - 0.012 14.8 13.0 0.03 13.5 9.0 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF3450 PF11932.3 CAM66173.1 - 0.014 14.7 1.7 0.014 14.7 1.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) CENP-H PF05837.7 CAM66173.1 - 0.025 14.7 6.5 0.025 14.7 4.5 1.6 2 0 0 2 2 2 0 Centromere protein H (CENP-H) CCDC155 PF14662.1 CAM66173.1 - 0.057 13.0 15.6 0.14 11.7 10.8 1.8 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 KLRAQ PF10205.4 CAM66173.1 - 0.059 13.4 6.4 0.16 12.0 4.4 1.8 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein PriCT_1 PF08708.6 CAM66173.1 - 0.084 12.7 0.2 0.18 11.6 0.1 1.7 1 0 0 1 1 1 0 Primase C terminal 1 (PriCT-1) RTBV_P46 PF06216.6 CAM66173.1 - 0.12 11.1 1.7 0.16 10.8 1.1 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein CALCOCO1 PF07888.6 CAM66173.1 - 0.16 10.2 10.7 0.2 9.9 7.4 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Herpes_BLRF2 PF05812.7 CAM66173.1 - 0.32 10.8 9.7 3.9 7.3 3.8 2.9 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein DUF2935 PF11155.3 CAM66173.1 - 0.35 10.9 3.5 0.85 9.7 2.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) DUF972 PF06156.8 CAM66173.1 - 0.44 10.9 10.0 1.3 9.4 6.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) TMF_TATA_bd PF12325.3 CAM66173.1 - 0.46 10.2 12.4 0.079 12.6 5.8 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding V_ATPase_I PF01496.14 CAM66173.1 - 0.48 8.2 4.0 0.53 8.0 2.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 CAM66173.1 - 0.87 9.1 7.6 0.54 9.7 3.2 2.2 2 1 1 3 3 3 0 Septum formation initiator TMF_DNA_bd PF12329.3 CAM66173.1 - 1.7 8.5 19.4 0.53 10.1 0.2 3.4 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding DivIVA PF05103.8 CAM66173.1 - 2.5 8.1 9.4 13 5.8 6.4 2.1 1 1 0 1 1 1 0 DivIVA protein Tnp_P_element PF12017.3 CAM66173.1 - 2.7 7.1 4.6 2.3 7.3 1.8 1.8 1 1 1 2 2 2 0 Transposase protein Rho_Binding PF08912.6 CAM66173.1 - 3.9 7.8 12.9 9.1 6.6 2.0 3.3 3 0 0 3 3 3 0 Rho Binding APG6 PF04111.7 CAM66173.1 - 4.3 6.2 13.1 0.55 9.2 6.0 1.6 1 1 1 2 2 2 0 Autophagy protein Apg6 TBPIP PF07106.8 CAM66173.1 - 7.7 6.0 10.7 1.7 8.1 3.4 2.0 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) COPIIcoated_ERV PF07970.7 CAM66174.1 - 3.9e-54 183.6 0.0 5.2e-54 183.2 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CAM66174.1 - 4.4e-19 68.2 0.0 7.6e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Hexapep PF00132.19 CAM66175.1 - 9.2e-13 47.0 5.7 1.2e-05 24.5 0.3 3.3 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CAM66175.1 - 0.02 14.4 2.4 4.2 7.0 0.2 3.3 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase ABC_tran PF00005.22 CAM66176.1 - 8.2e-28 97.4 0.0 1.9e-27 96.2 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 CAM66176.1 - 6.7e-07 29.5 1.2 0.00093 19.2 0.0 2.1 1 1 0 2 2 2 2 AAA domain AAA_10 PF12846.2 CAM66176.1 - 5.8e-05 22.6 0.7 0.26 10.6 0.3 2.4 2 0 0 2 2 2 2 AAA-like domain SMC_N PF02463.14 CAM66176.1 - 0.0012 18.1 0.3 0.015 14.5 0.0 2.0 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CAM66176.1 - 0.0044 17.0 0.1 0.014 15.3 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 CAM66176.1 - 0.005 16.3 0.2 0.011 15.2 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 CAM66176.1 - 0.0064 15.6 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CAM66176.1 - 0.0067 16.5 0.5 0.64 10.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CAM66176.1 - 0.0099 15.2 1.0 0.21 10.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 CAM66176.1 - 0.087 12.2 0.1 0.25 10.7 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family SbcCD_C PF13558.1 CAM66176.1 - 0.09 12.7 0.2 0.09 12.7 0.2 3.0 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 CAM66176.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CAM66176.1 - 0.14 11.8 0.2 0.45 10.1 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase DUF1341 PF07071.6 CAM66176.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1341) AAA_17 PF13207.1 CAM66176.1 - 0.16 12.7 0.9 0.5 11.2 0.1 2.1 2 1 0 2 2 2 0 AAA domain SNF2_N PF00176.18 CAM66177.1 - 2e-25 89.2 0.0 3.2e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HNH PF01844.18 CAM66177.1 - 2.9e-10 39.8 0.1 2.9e-10 39.8 0.1 2.6 2 0 0 2 2 2 1 HNH endonuclease Helicase_C PF00271.26 CAM66177.1 - 0.00018 21.3 0.0 0.00037 20.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAM66177.1 - 0.077 12.8 0.0 0.86 9.4 0.0 2.4 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Pkinase PF00069.20 CAM66178.1 - 5e-41 140.5 0.0 8.8e-28 97.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAM66178.1 - 4.3e-17 62.0 0.0 5.2e-10 38.8 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase NCD1 PF04904.8 CAM66178.1 - 0.012 15.3 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) APH PF01636.18 CAM66178.1 - 0.028 14.1 0.0 0.076 12.7 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family GRIP PF01465.15 CAM66179.1 - 1.3e-14 53.3 0.0 3e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 GRIP domain Cep57_CLD_2 PF14197.1 CAM66179.1 - 0.031 14.2 243.4 0.12 12.3 7.4 16.5 8 4 9 17 17 17 0 Centrosome localisation domain of PPC89 Rsa3 PF14615.1 CAM66179.1 - 0.046 13.0 25.5 61 3.0 0.0 9.2 10 0 0 10 10 10 0 Ribosome-assembly protein 3 Adhesin_P1 PF03257.8 CAM66179.1 - 0.048 13.9 0.1 0.28 11.5 0.1 2.4 1 0 0 1 1 1 0 Mycoplasma adhesin P1 CENP-F_leu_zip PF10473.4 CAM66179.1 - 0.14 12.0 211.0 0.034 14.0 3.6 13.4 5 2 10 15 15 15 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3240 PF11582.3 CAM66179.1 - 1.5 8.7 13.9 4.7 7.2 0.6 4.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3240) RRM_1 PF00076.17 CAM66180.1 - 1.1e-05 24.9 0.1 4.6e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4636 PF15468.1 CAM66180.1 - 0.0076 15.7 3.1 0.011 15.2 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4636) DUF2765 PF10963.3 CAM66180.1 - 0.03 14.2 0.2 0.33 10.9 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2765) MORN PF02493.15 CAM66181.1 - 5.4e-26 88.7 32.3 1.6e-06 27.4 0.8 6.5 6 0 0 6 6 6 6 MORN repeat tRNA-synt_2b PF00587.20 CAM66182.1 - 1.4e-32 112.6 0.0 2.7e-32 111.6 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 CAM66182.1 - 4.7e-14 52.3 4.0 1.6e-13 50.6 0.4 2.3 1 1 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Filo_VP35 PF02097.10 CAM66182.1 - 0.1 11.8 0.5 0.15 11.1 0.4 1.2 1 0 0 1 1 1 0 Filoviridae VP35 Pkinase PF00069.20 CAM66183.1 - 1.5e-49 168.4 0.0 1.9e-49 168.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM66183.1 - 1.9e-26 92.6 0.0 2.7e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM66183.1 - 9.7e-10 37.8 0.0 2.1e-09 36.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CAM66183.1 - 0.00016 21.5 0.8 0.00078 19.2 0.1 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CAM66183.1 - 0.0024 16.7 0.2 0.0038 16.1 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.9 CAM66183.1 - 0.0064 15.5 0.1 0.013 14.5 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CAM66183.1 - 0.016 14.6 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 CAM66183.1 - 0.021 14.3 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase NIF3 PF01784.13 CAM66185.1 - 4.5e-64 216.3 0.0 5.3e-64 216.1 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) PSP1 PF04468.7 CAM66186.1 - 1.6e-30 104.8 0.1 3e-30 104.0 0.1 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Macoilin PF09726.4 CAM66187.1 - 3 6.0 27.2 4.6 5.3 18.9 1.2 1 0 0 1 1 1 0 Transmembrane protein 3-PAP PF12578.3 CAM66189.2 - 1.5e-32 112.3 0.4 1.5e-32 112.3 0.3 3.1 3 0 0 3 3 3 1 Myotubularin-associated protein Dzip-like_N PF13815.1 CAM66189.2 - 0.0012 18.6 0.6 0.0012 18.6 0.4 3.2 2 1 1 3 3 3 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal PUA PF01472.15 CAM66190.1 - 5.3e-15 54.8 1.2 9.4e-15 54.1 0.8 1.4 1 0 0 1 1 1 1 PUA domain DUF4160 PF13711.1 CAM66190.1 - 0.012 15.4 0.2 0.024 14.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4160) FumaraseC_C PF10415.4 CAM66190.1 - 0.082 12.9 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Fumarase C C-terminus FIST PF08495.5 CAM66190.1 - 0.15 11.1 0.7 0.31 10.1 0.1 1.7 2 0 0 2 2 2 0 FIST N domain RPAP1_N PF08621.5 CAM66190.1 - 0.54 9.8 2.6 1.4 8.5 0.6 2.0 2 0 0 2 2 2 0 RPAP1-like, N-terminal DEAD PF00270.24 CAM66191.1 - 1.6e-21 76.5 0.0 2.5e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM66191.1 - 3.4e-08 33.2 0.0 1e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAM66191.1 - 7.5e-05 22.6 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit GCIP PF13324.1 CAM66192.1 - 0.0025 17.0 0.1 0.0029 16.8 0.1 1.2 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting Pyrophosphatase PF00719.14 CAM66193.2 - 2.6e-49 166.6 0.1 4e-49 166.0 0.0 1.3 1 0 0 1 1 1 1 Inorganic pyrophosphatase EF-hand_7 PF13499.1 CAM66193.2 - 0.002 18.2 0.3 0.012 15.7 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CAM66193.2 - 0.26 10.6 1.6 4.3 6.8 0.0 3.3 3 0 0 3 3 3 0 EF hand Pterin_4a PF01329.14 CAM66194.1 - 1.3e-30 104.9 0.1 1.4e-30 104.8 0.1 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Rad51 PF08423.6 CAM66195.1 - 5.9e-16 58.1 0.0 1.1e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 CAM66195.1 - 1.7e-12 47.1 0.6 2.9e-12 46.4 0.4 1.3 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 CAM66195.1 - 1.1e-06 27.9 0.0 4.6e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 KaiC DnaB_C PF03796.10 CAM66195.1 - 2e-06 26.9 0.0 0.025 13.4 0.0 2.1 2 0 0 2 2 2 2 DnaB-like helicase C terminal domain AAA PF00004.24 CAM66195.1 - 1.7e-05 24.9 0.0 6.9e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CAM66195.1 - 0.00018 21.6 0.1 0.00035 20.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CAM66195.1 - 0.0028 17.3 0.2 0.0028 17.3 0.1 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 CAM66195.1 - 0.0071 16.2 0.4 0.027 14.3 0.3 2.2 1 1 0 1 1 1 1 AAA domain RecA PF00154.16 CAM66195.1 - 0.011 14.8 0.1 0.023 13.7 0.0 1.4 2 0 0 2 2 2 0 recA bacterial DNA recombination protein AAA_16 PF13191.1 CAM66195.1 - 0.032 14.2 3.7 0.17 11.8 2.7 2.0 1 1 1 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 CAM66195.1 - 0.045 14.5 0.1 0.084 13.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 CAM66195.1 - 0.089 12.5 0.1 0.31 10.7 0.1 1.9 1 1 0 1 1 1 0 NTPase AAA_18 PF13238.1 CAM66195.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Proteasome PF00227.21 CAM66196.1 - 1.4e-58 197.3 0.1 1.9e-58 196.9 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CAM66196.1 - 8.3e-15 53.7 0.2 1.4e-14 53.0 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature EF-hand_like PF09279.6 CAM66196.1 - 0.011 15.7 1.3 0.17 11.9 1.4 2.4 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like DUF365 PF04033.7 CAM66196.1 - 0.014 15.3 0.6 0.028 14.4 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF365) Pkinase PF00069.20 CAM66197.2 - 3.5e-47 160.7 0.0 5.4e-41 140.4 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAM66197.2 - 2.9e-28 98.6 0.0 1.8e-22 79.6 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.1 CAM66197.2 - 4.1e-07 29.2 0.0 0.0055 15.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like YrbL-PhoP_reg PF10707.4 CAM66197.2 - 0.087 12.1 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL PEPCK_ATP PF01293.15 CAM66198.1 - 0.0026 16.3 0.0 0.0038 15.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase FAD_binding_6 PF00970.19 CAM66199.1 - 1.1e-07 31.8 0.0 3.1e-07 30.4 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 CAM66199.1 - 0.0037 17.8 0.0 0.056 14.0 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain SlyX PF04102.7 CAM66201.1 - 0.033 14.5 0.9 0.1 12.9 0.6 1.8 1 0 0 1 1 1 0 SlyX CCDC74_C PF14917.1 CAM66201.1 - 0.048 13.7 1.4 0.075 13.0 0.2 2.0 2 0 0 2 2 2 0 Coiled coil protein 74, C terminal Sec20 PF03908.8 CAM66202.1 - 5e-09 35.7 3.3 1.2e-08 34.5 2.3 1.6 1 0 0 1 1 1 1 Sec20 DUF2562 PF10814.3 CAM66202.1 - 0.0063 16.4 1.7 0.0063 16.4 1.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2562) THOC7 PF05615.8 CAM66202.1 - 0.48 10.6 5.7 3.5 7.8 1.1 2.3 2 1 0 2 2 2 0 Tho complex subunit 7 DASH_Dad2 PF08654.5 CAM66202.1 - 0.54 10.2 3.9 0.27 11.2 1.0 1.7 2 0 0 2 2 2 0 DASH complex subunit Dad2 Adeno_PIX PF03955.9 CAM66202.1 - 9.8 6.7 8.9 1.1 9.8 1.7 2.3 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) BLOC1_2 PF10046.4 CAM66203.1 - 1.3 9.2 5.3 13 6.0 0.2 2.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PIF1 PF05970.9 CAM66204.1 - 3.3e-30 105.2 0.9 7e-23 81.1 0.6 3.6 3 1 0 3 3 3 3 PIF1-like helicase AAA_30 PF13604.1 CAM66204.1 - 3.7e-16 59.2 0.0 9.9e-16 57.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CAM66204.1 - 0.00057 20.0 0.8 0.006 16.7 0.6 2.6 1 1 0 1 1 1 1 AAA domain DUF853 PF05872.7 CAM66204.1 - 0.0013 17.2 1.8 0.0027 16.1 1.2 1.5 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) AAA_19 PF13245.1 CAM66204.1 - 0.002 17.8 1.0 0.01 15.5 0.7 2.3 1 0 0 1 1 1 1 Part of AAA domain Herpes_Helicase PF02689.9 CAM66204.1 - 0.0053 14.5 0.6 0.27 8.9 0.0 2.4 3 0 0 3 3 3 2 Helicase UvrD_C_2 PF13538.1 CAM66204.1 - 0.034 14.3 0.0 0.16 12.1 0.0 2.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF87 PF01935.12 CAM66204.1 - 1.3 8.7 2.4 1.6 8.4 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function DUF87 PIF1 PF05970.9 CAM66205.1 - 2.2e-35 122.2 0.6 7.8e-28 97.4 0.1 3.4 2 1 1 3 3 3 3 PIF1-like helicase AAA_30 PF13604.1 CAM66205.1 - 1e-13 51.3 0.4 5.8e-13 48.8 0.0 2.4 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.1 CAM66205.1 - 3e-05 24.1 0.0 9.5e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CAM66205.1 - 6.4e-05 22.6 5.3 0.00051 19.7 2.4 3.3 2 0 0 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 CAM66205.1 - 0.0035 17.0 0.0 0.012 15.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 CAM66205.1 - 0.0053 16.9 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 CAM66205.1 - 0.0053 16.2 0.1 4.5 6.7 0.0 2.9 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Herpes_Helicase PF02689.9 CAM66205.1 - 0.0054 14.5 0.4 0.029 12.1 0.0 1.9 2 0 0 2 2 2 1 Helicase AAA_16 PF13191.1 CAM66205.1 - 0.0058 16.6 3.1 0.01 15.8 0.1 2.8 3 0 0 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.16 CAM66205.1 - 0.0095 15.1 1.8 0.011 14.9 0.1 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 CAM66205.1 - 0.011 15.3 0.1 0.81 9.2 0.0 2.8 1 1 1 2 2 2 0 AAA domain PhoH PF02562.11 CAM66205.1 - 0.015 14.5 0.1 0.04 13.1 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein UvrD_C_2 PF13538.1 CAM66205.1 - 0.03 14.4 0.0 0.099 12.7 0.0 2.0 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain NACHT PF05729.7 CAM66205.1 - 0.1 12.2 0.1 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain MobB PF03205.9 CAM66205.1 - 0.14 11.8 0.3 0.34 10.6 0.2 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 CAM66205.1 - 0.21 11.2 1.2 0.66 9.6 0.1 2.1 2 0 0 2 2 2 0 NTPase UvrD-helicase PF00580.16 CAM66205.1 - 0.29 10.4 0.0 0.48 9.6 0.0 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DUF2075 PF09848.4 CAM66205.1 - 0.29 10.0 0.2 0.61 8.9 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) 14-3-3 PF00244.15 CAM66207.1 - 5.9e-93 310.2 1.7 6.9e-93 310.0 1.2 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 CAM66207.1 - 0.08 12.8 1.0 5.4 7.0 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat OPA3 PF07047.7 CAM66208.1 - 2.1e-16 59.9 0.2 1.4e-09 37.8 0.0 2.3 2 0 0 2 2 2 2 Optic atrophy 3 protein (OPA3) SpaB_C PF14028.1 CAM66208.1 - 0.1 12.1 5.1 0.022 14.3 1.0 1.7 2 0 0 2 2 2 0 SpaB C-terminal domain Herpes_UL25 PF01499.11 CAM66208.1 - 0.18 10.0 0.0 0.18 10.0 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus UL25 family DUF2779 PF11074.3 CAM66210.1 - 7.2e-44 148.9 0.0 1.2e-43 148.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function(DUF2779) DUF4644 PF15486.1 CAM66211.1 - 0.015 15.2 0.5 0.04 13.8 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4644) TTL PF03133.10 CAM66212.1 - 2.5e-68 230.1 0.1 4e-68 229.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 CAM66212.1 - 6.9e-07 28.3 0.1 0.00033 19.5 0.0 3.1 2 1 1 3 3 3 2 YheC/D like ATP-grasp ATP-grasp_3 PF02655.9 CAM66212.1 - 0.0049 16.7 0.0 0.017 14.9 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain BOP1NT PF08145.7 CAM66213.1 - 2.8e-89 299.3 8.4 5.2e-89 298.4 5.8 1.5 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 CAM66213.1 - 4.2e-26 89.8 0.6 1.3e-10 40.7 0.0 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CAM66213.1 - 0.12 11.8 0.0 35 3.9 0.0 3.2 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain RCC1 PF00415.13 CAM66214.1 - 4.6e-21 74.7 17.4 1.9e-05 24.7 0.8 8.6 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CAM66214.1 - 4.9e-11 41.9 20.4 1.8e-06 27.4 0.3 5.9 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat DUF822 PF05687.8 CAM66215.1 - 0.37 11.1 2.5 0.79 10.0 1.7 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) LRR_4 PF12799.2 CAM66216.1 - 2.9e-16 58.6 12.8 2.3e-05 23.8 0.1 4.4 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM66216.1 - 2.3e-11 43.2 19.3 0.00014 21.5 2.1 3.8 2 1 2 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 CAM66216.1 - 7.5e-06 25.2 22.3 3.1 8.1 0.1 7.5 8 1 1 9 9 9 5 Leucine Rich Repeat LRR_6 PF13516.1 CAM66216.1 - 0.00023 20.8 17.0 0.53 10.5 0.1 6.3 5 2 2 7 7 7 2 Leucine Rich repeat LRR_7 PF13504.1 CAM66216.1 - 0.0008 19.2 27.7 0.65 10.4 0.1 7.8 8 0 0 8 8 8 3 Leucine rich repeat LRR_9 PF14580.1 CAM66216.1 - 0.014 14.9 2.1 0.53 9.8 0.8 2.2 1 1 1 2 2 2 0 Leucine-rich repeat DNA_ligase_A_M PF01068.16 CAM66217.1 - 0.0025 17.2 0.0 2.6 7.3 0.0 3.2 3 0 0 3 3 3 2 ATP dependent DNA ligase domain DNA_ligase_OB_2 PF14743.1 CAM66217.1 - 0.052 13.2 0.0 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 DNA ligase OB-like domain PUF PF00806.14 CAM66219.1 - 1.5e-09 36.7 0.0 1.5 8.4 0.0 5.8 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat Cyt-b5 PF00173.23 CAM66221.1 - 9.2e-20 70.2 0.1 1.4e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Tex_N PF09371.5 CAM66223.1 - 1.6e-45 154.7 0.4 3.4e-45 153.7 0.2 1.6 1 0 0 1 1 1 1 Tex-like protein N-terminal domain HHH_3 PF12836.2 CAM66223.1 - 3.2e-10 39.7 0.0 7.2e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 CAM66223.1 - 3.5e-06 26.6 0.0 7.4e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.1 CAM66223.1 - 0.0003 20.8 0.0 0.001 19.1 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif S1 PF00575.18 CAM66223.1 - 0.015 15.3 0.0 0.036 14.1 0.0 1.7 1 0 0 1 1 1 0 S1 RNA binding domain DUF655 PF04919.7 CAM66223.1 - 0.12 12.1 0.0 0.68 9.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF655) Nucleoside_tran PF01733.13 CAM66224.1 - 1.1e-34 120.0 6.3 2.1e-25 89.5 0.2 2.4 2 0 0 2 2 2 2 Nucleoside transporter DUF563 PF04577.9 CAM66225.1 - 1.9e-13 50.8 0.2 4.9e-13 49.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF563) AA_permease_2 PF13520.1 CAM66227.1 - 3.2e-20 72.0 36.9 4.5e-20 71.5 25.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CAM66227.1 - 9.1e-08 30.8 33.7 2.1e-07 29.6 23.4 1.6 1 1 0 1 1 1 1 Amino acid permease Pkinase PF00069.20 CAM66228.1 - 4.1e-34 117.8 0.0 8.1e-34 116.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM66228.1 - 3.3e-14 52.5 0.0 1.5e-11 43.9 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CAM66228.1 - 0.0017 17.2 0.2 0.0025 16.6 0.1 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 CAM66228.1 - 0.025 13.9 0.0 0.052 12.8 0.0 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 CAM66228.1 - 0.057 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family TPR_11 PF13414.1 CAM66230.1 - 1.2e-27 95.3 23.2 2e-11 43.3 0.1 5.9 3 1 4 7 7 7 5 TPR repeat TPR_2 PF07719.12 CAM66230.1 - 1.1e-16 59.3 14.9 2.4e-06 27.0 0.0 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.23 CAM66230.1 - 3.3e-16 58.1 20.9 9.6e-06 24.9 0.8 6.8 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 CAM66230.1 - 1.1e-12 48.2 6.2 0.0012 19.4 0.0 5.1 3 3 2 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 CAM66230.1 - 1.5e-09 37.3 13.5 0.021 14.9 0.2 6.0 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 CAM66230.1 - 4.7e-08 32.8 11.7 0.0064 16.4 0.2 4.4 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CAM66230.1 - 7.7e-08 31.5 11.9 0.0019 17.8 1.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 CAM66230.1 - 4.4e-07 29.9 4.2 0.079 13.4 0.1 5.1 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 CAM66230.1 - 5.2e-07 28.9 7.2 0.0018 17.9 0.0 4.6 5 1 1 6 6 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 CAM66230.1 - 3.6e-06 27.2 10.7 0.2 12.0 0.2 4.6 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 CAM66230.1 - 0.00025 21.4 12.1 0.16 12.7 0.1 5.1 6 1 1 7 7 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 CAM66230.1 - 0.00045 19.3 0.4 0.0066 15.5 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 CAM66230.1 - 0.0014 18.4 0.4 0.13 12.1 0.0 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat FAT PF02259.18 CAM66230.1 - 0.005 15.8 0.3 0.021 13.8 0.0 2.2 2 2 0 2 2 2 1 FAT domain Apc3 PF12895.2 CAM66230.1 - 0.0072 16.4 5.1 0.065 13.3 0.5 4.4 3 1 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF3808 PF10300.4 CAM66230.1 - 0.013 14.1 0.4 0.033 12.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3808) RPN7 PF10602.4 CAM66230.1 - 0.026 13.9 0.5 0.86 8.9 0.2 3.1 3 0 0 3 3 3 0 26S proteasome subunit RPN7 Fis1_TPR_C PF14853.1 CAM66230.1 - 0.035 13.9 0.1 0.63 9.9 0.0 2.9 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 CAM66230.1 - 0.058 13.3 0.4 5.5 7.0 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 CAM66230.1 - 2.1 8.2 17.5 1.2 9.0 0.3 4.7 5 1 0 5 5 5 0 MIT (microtubule interacting and transport) domain Pox_MCEL PF03291.11 CAM66231.2 - 6.1e-15 54.9 0.0 9.4e-15 54.2 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.1 CAM66231.2 - 2e-06 28.1 0.0 1.4e-05 25.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CAM66231.2 - 5.5e-06 26.7 0.0 0.00016 22.1 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAM66231.2 - 6.5e-06 26.5 0.0 3.7e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAM66231.2 - 1.9e-05 24.4 0.0 3.7e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAM66231.2 - 2.9e-05 24.6 0.0 0.00032 21.2 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain NSP13 PF06460.7 CAM66231.2 - 0.00067 18.6 0.1 0.0011 17.8 0.1 1.2 1 0 0 1 1 1 1 Coronavirus NSP13 PAM2 PF07145.10 CAM66231.2 - 0.035 13.6 0.8 0.1 12.1 0.6 1.8 1 0 0 1 1 1 0 Ataxin-2 C-terminal region TPMT PF05724.6 CAM66231.2 - 0.047 13.1 0.0 0.13 11.7 0.0 1.6 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.1 CAM66231.2 - 0.098 12.2 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 CAM66231.2 - 0.1 11.9 0.0 0.31 10.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain FmrO PF07091.6 CAM66231.2 - 0.13 11.2 0.0 0.26 10.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) PHF5 PF03660.9 CAM66231.2 - 0.46 10.5 5.4 0.1 12.6 1.1 1.8 2 0 0 2 2 1 0 PHF5-like protein Carboxyl_trans PF01039.17 CAM66232.1 - 6.6e-146 486.5 0.0 8.8e-146 486.0 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 CAM66232.1 - 1.3e-07 31.0 0.1 0.0022 17.2 0.0 2.2 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) zf-C4H2 PF10146.4 CAM66233.1 - 0.0053 16.8 0.7 0.0093 16.0 0.5 1.4 1 0 0 1 1 1 1 Zinc finger-containing protein Peptidase_M17 PF00883.16 CAM66235.1 - 1.9e-77 260.2 0.1 2.3e-77 259.9 0.1 1.0 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain DUF3132 PF11330.3 CAM66235.1 - 0.054 13.3 0.0 0.093 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3132) Peptidase_M17 PF00883.16 CAM66236.1 - 1.5e-85 286.8 0.1 2e-85 286.4 0.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain DUF3132 PF11330.3 CAM66236.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3132) MFS_1 PF07690.11 CAM66238.1 - 1.6e-22 79.7 28.5 1.7e-19 69.7 10.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 CAM66238.1 - 2e-08 33.8 10.7 2e-08 33.8 7.4 2.3 2 1 0 2 2 2 1 Nodulin-like SPC12 PF06645.8 CAM66238.1 - 1.2 8.9 0.0 1.2 8.9 0.0 3.6 5 0 0 5 5 5 0 Microsomal signal peptidase 12 kDa subunit (SPC12) MFS_1 PF07690.11 CAM66239.1 - 9.4e-14 50.8 28.6 8.5e-12 44.4 11.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 CAM66239.1 - 7.5e-09 35.2 13.7 7.5e-09 35.2 9.5 2.5 2 2 0 2 2 2 1 Nodulin-like ESSS PF10183.4 CAM66239.1 - 0.0061 16.9 1.1 0.029 14.7 0.0 2.7 2 0 0 2 2 2 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) MFS_1 PF07690.11 CAM66240.1 - 7.6e-14 51.1 45.3 2.4e-11 42.9 18.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 CAM66240.1 - 7e-07 28.7 22.9 7e-07 28.7 15.9 3.1 2 2 1 3 3 3 1 Nodulin-like COX8 PF02285.10 CAM66240.1 - 1.3 8.6 7.0 0.2 11.2 0.5 2.9 3 0 0 3 3 3 0 Cytochrome oxidase c subunit VIII MFS_1 PF07690.11 CAM66241.1 - 1.9e-13 49.8 41.5 7.2e-11 41.4 16.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 CAM66241.1 - 5e-07 29.2 21.0 5e-07 29.2 14.6 3.2 2 2 1 3 3 3 1 Nodulin-like COX8 PF02285.10 CAM66241.1 - 0.99 8.9 6.6 0.18 11.3 0.5 2.9 3 0 0 3 3 3 0 Cytochrome oxidase c subunit VIII Ank_2 PF12796.2 CAM66242.1 - 8.6e-33 112.5 0.7 1.4e-12 47.7 0.2 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CAM66242.1 - 1.1e-26 91.2 1.2 1.1e-07 31.3 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 CAM66242.1 - 3.1e-23 81.6 4.1 1.4e-07 31.7 0.0 4.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 CAM66242.1 - 1.3e-21 76.0 3.5 2.1e-06 27.8 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CAM66242.1 - 2.1e-18 64.5 0.4 0.00048 20.1 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat LpxK PF02606.9 CAM66242.1 - 0.096 11.6 0.1 1.5 7.7 0.0 2.0 2 0 0 2 2 2 0 Tetraacyldisaccharide-1-P 4'-kinase ArsA_ATPase PF02374.10 CAM66243.1 - 4.7e-89 298.4 0.1 1.4e-50 172.1 0.0 2.2 2 0 0 2 2 2 2 Anion-transporting ATPase CbiA PF01656.18 CAM66243.1 - 1e-10 41.3 2.4 7.4e-10 38.5 0.8 2.5 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.1 CAM66243.1 - 0.0011 18.4 0.1 0.003 16.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_31 PF13614.1 CAM66243.1 - 0.0051 16.7 0.0 0.031 14.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 CAM66243.1 - 0.031 13.6 0.4 1.9 7.8 0.1 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NB-ARC PF00931.17 CAM66243.1 - 0.042 12.7 0.1 0.074 11.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Fer4_NifH PF00142.13 CAM66243.1 - 0.16 11.1 0.0 0.66 9.1 0.0 1.9 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Peptidase_C11 PF03415.9 CAM66245.1 - 1.3e-05 24.3 0.0 1.9e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Clostripain family DUF1541 PF07563.6 CAM66247.1 - 0.046 13.4 0.5 0.5 10.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1541) MIT PF04212.13 CAM66248.1 - 0.011 15.5 0.5 0.022 14.6 0.4 1.6 1 1 0 1 1 1 0 MIT (microtubule interacting and transport) domain Ribosomal_S21e PF01249.13 CAM66249.1 - 1.9e-33 114.2 0.1 2.5e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S21e Chorion_2 PF03964.10 CAM66249.1 - 0.0029 18.1 4.9 0.0038 17.7 3.4 1.3 1 0 0 1 1 1 1 Chorion family 2 Ribosomal_S21e PF01249.13 CAM66250.1 - 5.5e-33 112.7 0.1 8.9e-33 112.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S21e COX6B PF02297.12 CAM66251.1 - 0.00053 19.9 9.4 0.097 12.7 1.1 2.9 1 1 1 2 2 2 2 Cytochrome oxidase c subunit VIb UPF0203 PF05254.7 CAM66251.1 - 0.014 15.2 8.6 8.4 6.3 0.3 3.6 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0203) EF-hand_6 PF13405.1 CAM66253.2 - 8e-13 47.1 0.1 0.13 12.2 0.0 6.9 7 0 0 7 7 7 3 EF-hand domain EF-hand_7 PF13499.1 CAM66253.2 - 5.6e-10 39.2 0.0 0.16 12.1 0.0 5.7 6 0 0 6 6 6 3 EF-hand domain pair EF-hand_1 PF00036.27 CAM66253.2 - 6.8e-05 21.8 0.0 1.3 8.5 0.0 5.1 7 0 0 7 7 7 2 EF hand EF-hand_8 PF13833.1 CAM66253.2 - 0.012 15.1 0.0 32 4.2 0.0 4.8 5 1 0 5 5 5 0 EF-hand domain pair DUF3552 PF12072.3 CAM66254.1 - 0.00017 20.9 14.1 0.00023 20.4 9.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) PAT1 PF09770.4 CAM66254.1 - 0.5 8.5 51.1 0.69 8.0 35.4 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DLIC PF05783.6 CAM66254.1 - 1.3 7.5 6.2 1.8 7.1 4.3 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) V_ATPase_I PF01496.14 CAM66254.1 - 1.4 6.6 6.7 1.8 6.3 4.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 CAM66254.1 - 2.2 7.2 13.9 2.9 6.8 9.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 LRS4 PF10422.4 CAM66255.1 - 0.0086 15.4 7.0 0.033 13.5 4.8 2.0 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 AAA_13 PF13166.1 CAM66255.1 - 0.35 9.2 8.5 0.51 8.7 5.9 1.1 1 0 0 1 1 1 0 AAA domain Borrelia_P83 PF05262.6 CAM66255.1 - 0.42 8.8 8.8 0.6 8.3 6.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF342 PF03961.8 CAM66255.1 - 0.58 8.5 7.1 0.89 7.9 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Spc7 PF08317.6 CAM66255.1 - 0.59 8.7 11.3 1 7.9 7.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein CDC37_N PF03234.9 CAM66255.1 - 0.8 10.0 11.1 1.6 9.0 7.7 1.5 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding TMF_DNA_bd PF12329.3 CAM66255.1 - 1.1 9.0 24.5 0.056 13.2 8.6 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 CAM66255.1 - 1.3 8.0 12.3 2.2 7.2 8.6 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 TMCO5 PF14992.1 CAM66255.1 - 1.9 7.5 9.8 2.9 6.9 6.8 1.2 1 0 0 1 1 1 0 TMCO5 family IncA PF04156.9 CAM66255.1 - 4.3 6.8 22.5 0.59 9.7 12.4 1.9 2 0 0 2 2 2 0 IncA protein DUF1423 PF07227.6 CAM66255.1 - 6.3 5.3 11.0 9.7 4.7 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) V_ATPase_I PF01496.14 CAM66255.1 - 9.5 3.9 6.3 14 3.3 4.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Abhydrolase_6 PF12697.2 CAM66256.1 - 0.0002 21.2 0.1 0.00037 20.4 0.0 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CAM66256.1 - 0.0015 18.2 0.0 0.0022 17.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 CAM66256.1 - 0.029 13.9 0.0 0.039 13.5 0.0 1.1 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.2 CAM66257.1 - 2.3e-11 44.0 0.0 5.1e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CAM66257.1 - 1.9e-05 24.4 0.0 3.1e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAM66257.1 - 0.013 15.1 0.0 0.17 11.4 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 CAM66257.1 - 0.021 14.6 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase HEAT PF02985.17 CAM66258.1 - 0.0022 17.8 12.7 3.8 7.8 0.1 6.8 7 0 0 7 7 7 3 HEAT repeat Kinesin PF00225.18 CAM66259.1 - 0.0028 16.4 0.1 0.005 15.5 0.1 1.5 1 0 0 1 1 1 1 Kinesin motor domain ECH_C PF13766.1 CAM66259.1 - 0.15 12.2 2.2 0.48 10.5 1.5 1.9 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region START PF01852.14 CAM66260.1 - 7.4e-22 77.6 0.0 1.5e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 START domain LRR_6 PF13516.1 CAM66261.1 - 1e-23 80.6 12.1 0.079 13.0 0.0 12.2 12 0 0 12 12 12 7 Leucine Rich repeat LRR_4 PF12799.2 CAM66261.1 - 4.4e-16 58.0 11.2 0.0001 21.8 0.3 8.9 9 2 1 10 10 10 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CAM66261.1 - 2.1e-11 42.2 10.5 3.8 7.9 0.0 11.4 14 0 0 14 14 14 4 Leucine Rich Repeat LRR_8 PF13855.1 CAM66261.1 - 8.7e-10 38.2 17.3 0.0011 18.6 1.3 7.6 8 1 0 8 8 8 3 Leucine rich repeat LRR_7 PF13504.1 CAM66261.1 - 0.0033 17.3 24.9 8.5 7.0 0.0 10.6 13 0 0 13 13 13 1 Leucine rich repeat Ribosomal_L24e PF01246.15 CAM66262.1 - 3.7e-30 103.5 1.8 3.7e-30 103.5 1.2 2.5 2 0 0 2 2 2 1 Ribosomal protein L24e zf-FCS PF06467.9 CAM66262.1 - 0.00096 18.7 7.0 0.0016 18.0 4.8 1.3 1 0 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif DUF581 PF04570.9 CAM66262.1 - 0.47 9.7 3.5 1.2 8.4 2.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF581) zf-MYND PF01753.13 CAM66262.1 - 4.1 7.3 6.6 40 4.1 4.6 2.4 1 1 0 1 1 1 0 MYND finger AAA PF00004.24 CAM66263.2 - 6.7e-40 136.3 0.0 2.4e-39 134.5 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CAM66263.2 - 1.4e-05 25.2 0.0 3.4e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 CAM66263.2 - 0.00012 22.0 0.0 0.00026 20.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 CAM66263.2 - 0.0021 17.9 1.2 0.006 16.4 0.0 2.5 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.9 CAM66263.2 - 0.0029 17.3 0.2 0.042 13.5 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CAM66263.2 - 0.003 17.5 1.1 0.003 17.5 0.8 5.1 4 1 0 4 4 4 1 AAA ATPase domain IstB_IS21 PF01695.12 CAM66263.2 - 0.009 15.4 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 CAM66263.2 - 0.013 16.3 0.0 0.054 14.3 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CAM66263.2 - 0.03 14.6 0.0 0.082 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 CAM66263.2 - 0.05 12.7 0.1 0.094 11.8 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 CAM66263.2 - 0.068 12.2 0.1 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus COX5A PF02284.11 CAM66263.2 - 0.097 12.6 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va DUF1792 PF08759.6 CAM66263.2 - 0.34 10.4 0.1 0.58 9.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1792) Parvo_NS1 PF01057.12 CAM66263.2 - 0.61 8.9 0.5 1.3 7.8 0.0 1.6 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 PUB PF09409.5 CAM66264.1 - 5.2e-15 54.9 0.0 1.1e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 PUB domain SHOCT PF09851.4 CAM66264.1 - 5.1e-05 22.5 0.4 5.1e-05 22.5 0.3 2.1 2 0 0 2 2 2 1 Short C-terminal domain MoaE PF02391.12 CAM66264.1 - 0.049 13.4 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 MoaE protein DUF3299 PF11736.3 CAM66264.1 - 2 8.3 5.1 3.8 7.3 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3299) DUF1682 PF07946.9 CAM66264.1 - 5.8 5.6 10.6 8.5 5.1 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF4311 PF14188.1 CAM66266.1 - 0.63 9.5 0.2 1 8.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4311) Ribosomal_60s PF00428.14 CAM66267.1 - 0.029 14.7 1.4 0.029 14.7 1.0 3.2 3 0 0 3 3 3 0 60s Acidic ribosomal protein SPT6_acidic PF14632.1 CAM66267.1 - 0.065 13.4 0.1 0.065 13.4 0.1 2.5 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Ribosomal_S7 PF00177.16 CAM66268.1 - 2.1e-38 131.2 0.4 2.4e-38 131.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosomal_S7 PF00177.16 CAM66269.1 - 6.8e-36 123.0 0.2 7.5e-36 122.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e zf-HIT PF04438.11 CAM66270.1 - 8.8e-08 31.6 6.5 1.7e-07 30.7 4.5 1.5 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.13 CAM66270.1 - 0.012 15.4 4.1 0.026 14.4 2.8 1.6 1 0 0 1 1 1 0 MYND finger zf-FPG_IleRS PF06827.9 CAM66270.1 - 0.25 10.9 2.8 1.7 8.3 0.1 2.6 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Adaptin_N PF01602.15 CAM66271.1 - 6.2e-84 282.2 0.0 8.2e-84 281.7 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 CAM66271.1 - 1.5e-07 31.6 6.7 0.0021 18.2 0.2 5.3 3 2 1 4 4 4 3 HEAT repeats HEAT_EZ PF13513.1 CAM66271.1 - 0.001 19.4 13.1 2 9.0 0.2 6.5 5 2 1 6 6 6 2 HEAT-like repeat HEAT PF02985.17 CAM66271.1 - 0.017 15.1 0.7 17 5.8 0.0 4.7 5 0 0 5 5 5 0 HEAT repeat Cnd1 PF12717.2 CAM66271.1 - 0.093 12.5 0.0 0.8 9.5 0.0 2.5 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 PEP-utilizers_C PF02896.13 CAM66272.2 - 2.7e-101 338.3 0.0 4.2e-101 337.6 0.0 1.3 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.14 CAM66272.2 - 2.1e-59 201.2 0.0 4.4e-59 200.1 0.0 1.5 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.18 CAM66272.2 - 3.6e-22 77.7 0.3 9.3e-22 76.3 0.2 1.7 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain HTH_24 PF13412.1 CAM66272.2 - 0.0014 17.9 0.1 0.0034 16.7 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 CAM66272.2 - 0.0036 16.8 0.2 0.011 15.2 0.1 1.9 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain Sigma70_r4 PF04545.11 CAM66272.2 - 0.0084 15.3 0.0 0.029 13.6 0.0 1.9 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_11 PF08279.7 CAM66272.2 - 0.068 12.8 0.0 0.25 11.0 0.0 1.9 2 0 0 2 2 2 0 HTH domain Exo_endo_phos PF03372.18 CAM66273.1 - 7.8e-06 26.0 0.0 5.4e-05 23.2 0.0 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SecY PF00344.15 CAM66277.1 - 2.4e-86 289.8 8.4 2.9e-86 289.5 5.8 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 CAM66277.1 - 1.9e-16 59.2 0.1 4e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 Plug domain of Sec61p TMEM237 PF15383.1 CAM66277.1 - 0.00084 18.5 0.2 0.0014 17.7 0.1 1.3 1 0 0 1 1 1 1 Transmembrane protein 237 RHINO PF15319.1 CAM66279.1 - 0.012 15.4 0.0 0.012 15.4 0.0 2.8 3 0 0 3 3 3 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein zf-DHHC PF01529.15 CAM66280.1 - 3.4e-24 85.1 13.8 3.4e-24 85.1 9.6 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase Med15 PF09606.5 CAM66280.1 - 3.2 5.8 4.9 4.4 5.3 3.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal zf-DHHC PF01529.15 CAM66281.1 - 5.4e-23 81.2 16.5 5.4e-23 81.2 11.5 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase p450 PF00067.17 CAM66282.1 - 4.2e-66 223.3 0.0 5.1e-66 223.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L28e PF01778.12 CAM66283.1 - 6.7e-20 71.6 0.5 1.1e-19 71.0 0.1 1.4 1 1 0 1 1 1 1 Ribosomal L28e protein family bPH_6 PF10756.4 CAM66283.1 - 0.023 14.5 0.5 0.034 14.0 0.4 1.3 1 0 0 1 1 1 0 Bacterial PH domain ELFV_dehydrog_N PF02812.13 CAM66283.1 - 0.054 13.0 0.1 0.091 12.3 0.0 1.6 1 1 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Ribosomal_L28e PF01778.12 CAM66285.1 - 6.7e-20 71.6 0.5 1.1e-19 71.0 0.1 1.4 1 1 0 1 1 1 1 Ribosomal L28e protein family bPH_6 PF10756.4 CAM66285.1 - 0.023 14.5 0.5 0.034 14.0 0.4 1.3 1 0 0 1 1 1 0 Bacterial PH domain ELFV_dehydrog_N PF02812.13 CAM66285.1 - 0.054 13.0 0.1 0.091 12.3 0.0 1.6 1 1 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain WD40 PF00400.27 CAM66286.2 - 2.2e-16 59.0 18.2 3.6e-06 26.6 0.1 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat Sec16_C PF12931.2 CAM66286.2 - 0.015 15.0 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 GTP_EFTU PF00009.22 CAM66288.1 - 1e-43 149.0 0.0 2.6e-43 147.6 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CAM66288.1 - 3.7e-21 75.1 0.0 9.4e-21 73.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 CAM66288.1 - 0.00021 21.2 0.0 0.00052 19.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 CAM66288.1 - 0.0011 19.0 0.3 0.0079 16.2 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 G-alpha PF00503.15 CAM66288.1 - 0.0015 17.3 1.9 0.0015 17.3 1.3 2.0 2 0 0 2 2 2 1 G-protein alpha subunit 60KD_IMP PF02096.15 CAM66289.1 - 8.8e-27 94.0 0.1 1.2e-26 93.6 0.0 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein Ribosomal_S8 PF00410.14 CAM66290.1 - 2e-23 82.6 0.0 2.9e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Solute_trans_a PF03619.11 CAM66291.1 - 1.8e-84 283.2 17.9 2.3e-84 282.9 12.4 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Prok-RING_2 PF14445.1 CAM66291.1 - 0.082 12.8 0.6 0.21 11.5 0.4 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 Glycos_transf_2 PF00535.21 CAM66291.1 - 0.083 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Skp1 PF01466.14 CAM66292.1 - 1.2e-33 114.9 2.4 1.8e-33 114.4 1.7 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 CAM66292.1 - 1.4e-12 47.4 0.0 8.9e-12 44.9 0.0 2.2 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.26 CAM66292.1 - 0.035 14.0 0.0 0.5 10.3 0.0 2.2 2 0 0 2 2 2 0 BTB/POZ domain ABC_tran PF00005.22 CAM66293.1 - 2.4e-52 176.8 0.0 4.7e-26 91.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 CAM66293.1 - 1.2e-51 175.8 62.5 4.6e-36 124.5 17.2 2.7 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.1 CAM66293.1 - 5.2e-16 59.4 0.0 4.3e-07 30.1 0.0 4.4 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.1 CAM66293.1 - 1.5e-05 25.3 0.5 0.15 12.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CAM66293.1 - 0.00032 20.1 0.3 0.41 10.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SRP54 PF00448.17 CAM66293.1 - 0.00048 19.6 1.0 0.75 9.2 0.1 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain SbcCD_C PF13558.1 CAM66293.1 - 0.00082 19.2 0.0 0.73 9.7 0.0 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 CAM66293.1 - 0.0015 17.7 0.1 0.22 10.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 CAM66293.1 - 0.011 14.8 0.1 7.9 5.5 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin SMC_N PF02463.14 CAM66293.1 - 0.015 14.5 0.0 30 3.7 0.0 3.4 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 CAM66293.1 - 0.024 13.7 0.0 11 4.9 0.0 3.3 4 0 0 4 4 4 0 AAA ATPase domain AAA_30 PF13604.1 CAM66293.1 - 0.039 13.5 0.3 0.76 9.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CAM66293.1 - 0.039 13.3 0.1 11 5.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 CAM66293.1 - 0.086 13.0 0.2 2.7 8.2 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 CAM66293.1 - 0.19 11.3 1.4 8.6 6.0 0.0 2.7 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 CAM66293.1 - 0.22 11.2 0.5 4.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF4407 PF14362.1 CAM66293.1 - 0.31 9.9 3.0 0.83 8.5 2.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_10 PF12846.2 CAM66293.1 - 0.51 9.7 1.5 4.3 6.6 0.1 2.5 3 0 0 3 3 3 0 AAA-like domain DUF87 PF01935.12 CAM66293.1 - 1 9.1 2.4 1.5 8.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_13 PF13166.1 CAM66293.1 - 1.5 7.2 1.1 11 4.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF1049 PF06305.6 CAM66293.1 - 1.7 8.2 7.4 0.19 11.2 0.1 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) ABC2_membrane_3 PF12698.2 CAM66294.1 - 1.2e-33 116.5 9.3 1.8e-33 116.0 6.5 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.22 CAM66294.1 - 8.5e-22 77.9 0.0 1.5e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CAM66294.1 - 7e-06 26.2 0.0 0.001 19.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain SRP54 PF00448.17 CAM66294.1 - 0.016 14.6 0.1 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_10 PF12846.2 CAM66294.1 - 0.19 11.1 0.0 0.37 10.1 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_23 PF13476.1 CAM66294.1 - 0.52 10.5 1.9 0.87 9.8 1.3 1.2 1 0 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.2 CAM66295.1 - 6e-53 180.0 31.7 3.3e-34 118.4 6.0 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.22 CAM66295.1 - 7.5e-51 172.0 0.0 6e-27 94.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CAM66295.1 - 3e-15 56.9 0.0 3.9e-06 27.0 0.0 4.2 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 CAM66295.1 - 3.6e-06 26.3 0.0 0.0014 17.9 0.0 3.2 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 CAM66295.1 - 1.9e-05 24.4 1.0 0.035 14.0 0.0 4.2 3 2 0 3 3 3 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 CAM66295.1 - 8.6e-05 22.9 3.2 0.066 13.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain SRP54 PF00448.17 CAM66295.1 - 0.00024 20.6 0.5 0.09 12.2 0.0 2.3 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_29 PF13555.1 CAM66295.1 - 0.00031 20.2 0.9 0.28 10.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.1 CAM66295.1 - 0.00066 18.8 0.0 2.6 6.9 0.0 3.7 4 0 0 4 4 4 1 AAA ATPase domain DUF258 PF03193.11 CAM66295.1 - 0.0014 17.7 0.2 0.045 12.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 CAM66295.1 - 0.014 14.8 0.1 1.2 8.4 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_25 PF13481.1 CAM66295.1 - 0.023 14.1 0.1 5.2 6.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CAM66295.1 - 0.045 13.6 0.0 12 5.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 CAM66295.1 - 0.056 13.4 0.0 2.5 8.0 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 CAM66295.1 - 0.06 13.4 0.2 5.2 7.2 0.0 2.9 2 1 0 2 2 2 0 AAA domain UPF0079 PF02367.12 CAM66295.1 - 0.061 12.9 0.2 5.4 6.6 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 CAM66295.1 - 0.067 12.7 0.1 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 CAM66295.1 - 0.078 12.0 0.1 3.6 6.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin MobB PF03205.9 CAM66295.1 - 0.13 11.9 0.2 2.8 7.6 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 CAM66295.1 - 0.14 11.5 1.1 4.2 6.7 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 CAM66295.1 - 0.14 12.1 0.1 13 5.7 0.1 3.0 3 0 0 3 3 2 0 AAA domain Arf PF00025.16 CAM66295.1 - 0.19 10.9 0.3 4.1 6.6 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA PF00004.24 CAM66295.1 - 0.2 11.8 0.1 11 6.2 0.0 3.1 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.1 CAM66295.1 - 0.55 8.6 0.9 6.9 4.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 CAM66296.1 - 4.3e-52 176.0 0.0 5.1e-26 91.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 CAM66296.1 - 1.7e-50 172.0 67.9 2.2e-35 122.3 18.9 3.0 2 2 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 CAM66296.1 - 1.1e-12 48.5 0.0 0.0006 19.8 0.0 4.3 3 1 1 4 4 4 2 AAA domain AAA_23 PF13476.1 CAM66296.1 - 7e-06 26.5 0.3 0.16 12.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CAM66296.1 - 0.00015 21.1 0.3 0.44 10.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.1 CAM66296.1 - 0.00062 19.6 0.0 0.79 9.6 0.0 3.4 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SRP54 PF00448.17 CAM66296.1 - 0.00074 19.0 1.4 0.83 9.0 0.1 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain DUF258 PF03193.11 CAM66296.1 - 0.00094 18.3 0.1 0.24 10.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 CAM66296.1 - 0.0058 15.7 0.2 8.5 5.4 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin AAA_30 PF13604.1 CAM66296.1 - 0.032 13.8 0.3 0.81 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CAM66296.1 - 0.095 12.0 0.1 12 5.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA PF00004.24 CAM66296.1 - 0.1 12.8 0.1 3.4 7.8 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 CAM66296.1 - 0.1 12.2 0.3 9.2 5.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SMC_N PF02463.14 CAM66296.1 - 0.18 11.0 0.0 36 3.4 0.1 3.2 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain MobB PF03205.9 CAM66296.1 - 0.24 11.0 0.5 4.7 6.9 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.1 CAM66296.1 - 0.24 10.3 0.0 60 2.5 0.0 3.2 4 0 0 4 4 4 0 AAA ATPase domain AAA_10 PF12846.2 CAM66296.1 - 0.32 10.4 0.4 4.6 6.5 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain DUF4407 PF14362.1 CAM66296.1 - 1.4 7.8 3.8 4.2 6.2 2.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_13 PF13166.1 CAM66296.1 - 1.7 7.0 1.1 12 4.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 CAM66296.1 - 1.7 8.3 3.0 1.6 8.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 ABC2_membrane_3 PF12698.2 CAM66298.2 - 1.1e-59 202.2 64.8 5.3e-44 150.6 11.8 2.9 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.22 CAM66298.2 - 4.5e-50 169.4 0.0 1.3e-24 87.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CAM66298.2 - 3.3e-18 66.6 0.1 3.2e-07 30.6 0.0 4.3 4 0 0 4 4 4 3 AAA domain AAA_15 PF13175.1 CAM66298.2 - 4.6e-06 25.9 0.0 0.72 8.8 0.0 3.9 4 0 0 4 4 4 2 AAA ATPase domain SMC_N PF02463.14 CAM66298.2 - 9.2e-06 25.0 0.0 1.3 8.2 0.0 3.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 CAM66298.2 - 1.3e-05 25.0 0.0 0.036 13.9 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 CAM66298.2 - 2.2e-05 24.8 1.6 0.1 12.8 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 CAM66298.2 - 8e-05 22.0 1.0 0.27 10.8 0.0 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 CAM66298.2 - 0.00034 19.8 0.0 0.047 12.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SRP54 PF00448.17 CAM66298.2 - 0.0018 17.7 0.5 0.42 10.0 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_30 PF13604.1 CAM66298.2 - 0.01 15.4 0.1 0.62 9.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 CAM66298.2 - 0.017 14.7 0.4 6 6.5 0.0 2.8 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 CAM66298.2 - 0.021 13.9 0.1 9.8 5.2 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin AAA_33 PF13671.1 CAM66298.2 - 0.028 14.2 0.9 19 5.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 CAM66298.2 - 0.064 12.6 0.0 8.4 5.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Arf PF00025.16 CAM66298.2 - 0.072 12.3 0.0 4.1 6.6 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family cobW PF02492.14 CAM66298.2 - 0.08 12.3 0.3 4.7 6.6 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 CAM66298.2 - 0.17 12.1 0.0 3.5 7.8 0.0 2.7 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 CAM66298.2 - 0.17 12.4 0.1 36 4.8 0.0 2.9 2 0 0 2 2 2 0 Miro-like protein AAA_22 PF13401.1 CAM66298.2 - 0.18 11.9 0.1 8.2 6.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 CAM66298.2 - 0.21 11.5 0.3 12 5.8 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 CAM66298.2 - 0.22 11.5 0.0 5.7 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_13 PF13166.1 CAM66298.2 - 0.33 9.3 0.2 9.2 4.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC2_membrane PF01061.19 CAM66298.2 - 0.37 9.9 58.9 0.0054 15.9 11.2 4.5 4 0 0 4 4 4 0 ABC-2 type transporter DUF1049 PF06305.6 CAM66298.2 - 5.3 6.5 6.9 0.53 9.7 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) TatD_DNase PF01026.16 CAM66299.1 - 6.6e-46 156.5 0.0 9.2e-46 156.1 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.9 CAM66299.1 - 0.0017 18.0 0.0 0.014 15.0 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase ABC2_membrane_3 PF12698.2 CAM66300.1 - 1.7e-57 194.9 42.4 4.7e-38 131.0 11.1 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.22 CAM66300.1 - 1.6e-50 170.9 0.0 2.9e-26 92.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CAM66300.1 - 7.4e-20 72.0 0.0 1.5e-07 31.6 0.0 4.1 2 2 0 3 3 3 3 AAA domain SMC_N PF02463.14 CAM66300.1 - 1.3e-07 31.1 0.0 0.17 11.1 0.0 3.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CAM66300.1 - 2.6e-05 24.6 1.5 0.096 12.9 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.1 CAM66300.1 - 0.0002 20.5 0.0 1.3 8.0 0.0 3.6 4 0 0 4 4 4 2 AAA ATPase domain AAA_29 PF13555.1 CAM66300.1 - 0.00024 20.5 0.3 0.21 11.1 0.0 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 CAM66300.1 - 0.00036 19.7 0.0 0.055 12.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 CAM66300.1 - 0.00036 20.3 0.0 1.5 8.7 0.0 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SRP54 PF00448.17 CAM66300.1 - 0.00092 18.6 1.5 0.26 10.6 0.0 3.0 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.7 CAM66300.1 - 0.012 14.6 0.0 1.9 7.5 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.1 CAM66300.1 - 0.063 13.1 0.0 12 5.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 CAM66300.1 - 0.071 12.5 0.2 4.2 6.7 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 CAM66300.1 - 0.076 13.2 0.0 6.3 7.0 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CAM66300.1 - 0.084 12.8 0.0 0.83 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Arf PF00025.16 CAM66300.1 - 0.1 11.8 0.1 4.7 6.4 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family UPF0079 PF02367.12 CAM66300.1 - 0.11 12.0 0.1 6.2 6.4 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 CAM66300.1 - 0.11 11.8 0.0 21 4.3 0.0 3.4 3 0 0 3 3 3 0 AAA-like domain AAA_13 PF13166.1 CAM66300.1 - 0.11 10.8 0.2 3.9 5.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 CAM66300.1 - 0.14 12.7 0.0 43 4.6 0.0 3.0 2 0 0 2 2 2 0 Miro-like protein AAA_28 PF13521.1 CAM66300.1 - 0.25 11.3 3.2 8 6.3 0.1 3.8 4 0 0 4 4 4 0 AAA domain GvpK PF05121.7 CAM66301.1 - 0.11 12.2 1.2 0.66 9.8 0.0 2.6 3 0 0 3 3 3 0 Gas vesicle protein K GCOM2 PF15328.1 CAM66301.1 - 0.35 10.5 2.8 0.44 10.2 1.9 1.3 1 1 0 1 1 1 0 Putative GRINL1B complex locus protein 2 HEAT PF02985.17 CAM66302.1 - 0.001 18.9 13.0 10 6.4 0.0 5.3 6 0 0 6 6 6 4 HEAT repeat Arm PF00514.18 CAM66302.1 - 0.0013 18.4 6.9 0.0065 16.2 0.1 4.6 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 CAM66302.1 - 0.022 13.0 4.3 1.4 7.1 1.0 2.5 2 1 0 2 2 2 0 Adaptin N terminal region Proteasom_PSMB PF10508.4 CAM66302.1 - 0.026 12.8 1.9 0.036 12.3 0.7 1.6 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit HEAT_2 PF13646.1 CAM66302.1 - 0.026 14.8 21.9 0.039 14.2 0.6 4.5 1 1 2 3 3 3 0 HEAT repeats Tmemb_170 PF10190.4 CAM66302.1 - 0.27 11.3 4.1 0.17 11.9 0.6 2.1 1 1 1 2 2 2 0 Putative transmembrane protein 170 Frigida PF07899.6 CAM66303.1 - 0.093 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Frigida-like protein STAG PF08514.6 CAM66303.1 - 4 7.1 5.2 4.2 7.1 0.3 2.9 3 0 0 3 3 3 0 STAG domain PapD-like PF14874.1 CAM66304.1 - 7e-48 160.7 0.9 1.4e-47 159.8 0.6 1.5 1 0 0 1 1 1 1 Flagellar-associated PapD-like Nodulin-like PF06813.8 CAM66305.1 - 4.1e-16 59.0 10.4 4.1e-16 59.0 7.2 3.1 3 0 0 3 3 3 1 Nodulin-like MFS_1 PF07690.11 CAM66305.1 - 1.8e-10 40.0 46.7 7.4e-07 28.1 13.3 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF3450 PF11932.3 CAM66306.1 - 0.0023 17.2 1.0 0.0032 16.7 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) CCDC155 PF14662.1 CAM66306.1 - 0.0027 17.3 5.4 0.0035 16.9 3.7 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 IncA PF04156.9 CAM66306.1 - 0.0031 17.1 0.0 0.0034 17.0 0.0 1.1 1 0 0 1 1 1 1 IncA protein DUF4175 PF13779.1 CAM66306.1 - 0.019 12.7 4.1 0.023 12.4 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DivIC PF04977.10 CAM66306.1 - 0.042 13.3 0.9 0.042 13.3 0.7 2.1 1 1 1 2 2 2 0 Septum formation initiator DUF3323 PF11796.3 CAM66306.1 - 0.06 12.6 2.9 0.078 12.2 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) HAUS-augmin3 PF14932.1 CAM66306.1 - 0.064 12.4 3.8 0.083 12.0 2.6 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 BLOC1_2 PF10046.4 CAM66306.1 - 0.14 12.3 1.9 0.21 11.7 1.3 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6 PF04111.7 CAM66306.1 - 0.18 10.8 4.4 0.24 10.4 3.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 NYD-SP28_assoc PF14775.1 CAM66306.1 - 0.21 11.2 1.6 9.3 6.0 1.0 2.4 1 1 1 2 2 2 0 Sperm tail C-terminal domain DUF904 PF06005.7 CAM66306.1 - 1.2 9.4 7.8 0.63 10.3 3.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF904) FliT PF05400.8 CAM66306.1 - 1.4 9.3 8.6 9.3 6.7 5.9 2.0 1 1 0 1 1 1 0 Flagellar protein FliT ERM PF00769.14 CAM66306.1 - 1.7 8.1 8.5 2.2 7.7 5.9 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF972 PF06156.8 CAM66306.1 - 8.5 6.7 7.6 1.3 9.4 2.3 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Ribosomal_L4 PF00573.17 CAM66307.1 - 8.7e-10 38.2 0.0 2.3e-09 36.9 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein L4/L1 family TruD PF01142.13 CAM66308.1 - 4.8e-06 25.4 0.0 2e-05 23.4 0.0 2.0 2 1 0 2 2 2 1 tRNA pseudouridine synthase D (TruD) SH3_9 PF14604.1 CAM66309.1 - 2.7e-11 42.8 0.0 4.7e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CAM66309.1 - 2e-08 33.5 0.0 3.6e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CAM66309.1 - 2.9e-08 33.0 0.0 5.4e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Sec8_exocyst PF04048.9 CAM66309.1 - 7.2 6.2 6.3 25 4.5 0.1 3.1 4 0 0 4 4 4 0 Sec8 exocyst complex component specific domain IF-2B PF01008.12 CAM66310.2 - 1.3e-21 76.8 0.8 3e-17 62.5 0.3 3.0 2 1 0 2 2 2 2 Initiation factor 2 subunit family ALIX_LYPXL_bnd PF13949.1 CAM66310.2 - 0.017 14.0 0.2 0.024 13.5 0.1 1.1 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV PITH PF06201.8 CAM66311.2 - 1.1e-31 109.7 0.0 1.4e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 PITH domain Proteasome PF00227.21 CAM66312.2 - 1.3e-41 142.0 0.6 1.5e-41 141.7 0.4 1.1 1 0 0 1 1 1 1 Proteasome subunit Herp-Cyclin PF09241.5 CAM66312.2 - 0.13 12.5 0.0 1.5 9.1 0.0 2.3 3 0 0 3 3 3 0 Herpesviridae viral cyclin DAP3 PF10236.4 CAM66313.2 - 5.8e-29 101.0 0.0 8.9e-29 100.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 Arch_ATPase PF01637.13 CAM66313.2 - 0.013 15.1 0.0 0.05 13.2 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase AAA_19 PF13245.1 CAM66313.2 - 0.014 15.1 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 CAM66313.2 - 0.055 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain T2SE PF00437.15 CAM66313.2 - 0.23 10.3 0.0 0.34 9.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Metallophos PF00149.23 CAM66314.2 - 0.021 14.2 0.0 0.041 13.2 0.0 1.5 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase DUF3321 PF11968.3 CAM66314.2 - 0.05 13.2 0.6 0.46 10.0 0.2 2.1 2 0 0 2 2 2 0 Putative methyltransferase (DUF3321) Isochorismatase PF00857.15 CAM66315.2 - 8e-16 58.4 0.1 1.3e-15 57.7 0.1 1.4 1 1 0 1 1 1 1 Isochorismatase family DUF3024 PF11225.3 CAM66317.2 - 0.14 12.0 1.1 9.7 6.1 0.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3024) TPR_14 PF13428.1 CAM66318.2 - 0.017 15.7 2.2 21 6.1 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 CAM66318.2 - 0.11 12.4 0.0 3.1 7.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Plus-3 PF03126.13 CAM66319.2 - 1.9e-12 47.1 0.0 3.7e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Plus-3 domain zf-C3HC4_3 PF13920.1 CAM66319.2 - 1.7e-08 33.9 16.8 2.6e-08 33.3 11.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SelB-wing_1 PF09105.5 CAM66319.2 - 0.05 13.2 0.5 0.095 12.3 0.4 1.5 1 0 0 1 1 1 0 Elongation factor SelB, winged helix zf-C3HC4_2 PF13923.1 CAM66319.2 - 0.17 11.9 18.6 0.33 11.0 12.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Vps39_2 PF10367.4 CAM66319.2 - 0.85 9.8 9.2 2 8.6 6.4 1.7 1 1 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 FYVE PF01363.16 CAM66320.2 - 4.7e-09 36.0 5.1 2.1e-08 33.9 3.5 2.2 1 0 0 1 1 1 1 FYVE zinc finger Tropomyosin_1 PF12718.2 CAM66321.2 - 1.1e-05 25.2 7.5 1.1e-05 25.2 5.2 6.2 4 2 2 6 6 6 1 Tropomyosin like CENP-F_leu_zip PF10473.4 CAM66321.2 - 0.0059 16.4 3.9 0.0059 16.4 2.7 7.2 3 2 5 8 8 8 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin PF02996.12 CAM66321.2 - 0.46 10.1 13.8 0.046 13.3 0.8 5.3 3 1 1 4 4 4 0 Prefoldin subunit Fib_alpha PF08702.5 CAM66321.2 - 1.6 8.8 36.6 0.7 9.9 0.9 6.0 3 2 1 5 5 5 0 Fibrinogen alpha/beta chain family AAA_13 PF13166.1 CAM66321.2 - 3 6.1 33.7 0.0079 14.7 5.3 3.7 1 1 2 3 3 3 0 AAA domain DUF1664 PF07889.7 CAM66321.2 - 4.1 7.2 39.2 0.29 10.9 0.8 7.4 2 2 3 8 8 8 0 Protein of unknown function (DUF1664) Pkinase PF00069.20 CAM66322.2 - 7.1e-38 130.2 0.0 7.4e-18 64.6 0.0 3.6 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAM66322.2 - 2.6e-17 62.7 0.0 2.4e-09 36.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CAM66322.2 - 0.0011 18.7 0.6 1.2 8.7 0.0 2.5 1 1 0 2 2 2 2 Phosphotransferase enzyme family LRR_4 PF12799.2 CAM66324.2 - 1.1e-11 44.1 1.2 0.00029 20.3 0.0 4.4 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM66324.2 - 2.6e-10 39.8 0.7 0.0029 17.3 0.0 3.6 3 1 1 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 CAM66324.2 - 1.9e-07 30.1 0.2 26 5.3 0.0 6.5 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_7 PF13504.1 CAM66324.2 - 5.3e-05 22.7 5.4 6.1 7.5 0.1 6.3 6 0 0 6 6 6 1 Leucine rich repeat LRR_6 PF13516.1 CAM66324.2 - 0.00096 18.9 4.6 10 6.5 0.0 5.5 4 1 1 5 5 5 1 Leucine Rich repeat Helicase_C PF00271.26 CAM66335.2 - 5.9e-06 26.0 1.8 9.2e-06 25.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HA2 PF04408.18 CAM66335.2 - 3.7e-05 23.6 0.0 0.00015 21.6 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.24 CAM66335.2 - 0.00013 21.4 0.0 0.00091 18.7 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase zf-met PF12874.2 CAM66335.2 - 0.0069 16.5 2.9 0.017 15.3 2.0 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CAM66335.2 - 0.23 11.6 2.2 0.47 10.6 1.5 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding AKAP95 PF04988.7 CAM66335.2 - 1.9 8.2 0.5 3.6 7.3 0.4 1.4 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) SET PF00856.23 CAM66336.2 - 3.2e-05 24.2 2.9 0.053 13.8 2.0 3.6 1 1 0 1 1 1 1 SET domain LRR_4 PF12799.2 CAM66376.2 - 3.3e-14 52.1 0.0 0.00011 21.7 0.0 3.7 1 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CAM66376.2 - 2.5e-07 29.7 0.0 5.9 7.3 0.0 6.3 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_8 PF13855.1 CAM66376.2 - 7.5e-07 28.8 0.1 0.0068 16.1 0.0 3.1 1 1 2 3 3 3 2 Leucine rich repeat Mucin PF01456.12 CAM66376.2 - 1.9 8.2 41.8 0.061 13.1 24.2 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein WD40 PF00400.27 CAM66403.2 - 3.6e-09 36.1 5.4 0.21 11.5 0.5 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat LisH PF08513.6 CAM66403.2 - 0.16 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 LisH Prenyltransf PF01255.14 CAM66404.2 - 5.1e-54 182.7 0.2 5.6e-51 172.8 0.0 2.1 2 0 0 2 2 2 2 Putative undecaprenyl diphosphate synthase Maf1 PF09174.5 CAM66404.2 - 0.00022 21.1 0.0 0.00046 20.0 0.0 1.5 1 0 0 1 1 1 1 Maf1 regulator BicD PF09730.4 CAM66405.1 - 0.0064 14.9 0.5 0.008 14.5 0.3 1.0 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D GTPase_Cys_C PF12631.2 CAM66405.1 - 0.021 15.2 0.7 0.051 13.9 0.3 1.8 1 1 0 1 1 1 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE SCP-1 PF05483.7 CAM66405.1 - 0.053 11.3 0.4 0.064 11.0 0.3 1.0 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) IncA PF04156.9 CAM66405.1 - 0.065 12.8 2.4 0.11 12.1 1.7 1.3 1 0 0 1 1 1 0 IncA protein PspB PF06667.7 CAM66405.1 - 0.14 12.1 0.3 0.32 10.9 0.1 1.7 1 1 0 1 1 1 0 Phage shock protein B FUSC PF04632.7 CAM66406.2 - 6.3 5.0 7.8 8.9 4.6 5.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family RNase_HII PF01351.13 CAM66407.1 - 2.7e-18 66.3 0.1 5.7e-16 58.7 0.1 2.3 1 1 0 1 1 1 1 Ribonuclease HII DNA_pol_A PF00476.15 CAM66410.1 - 1.2e-27 96.5 0.0 4.1e-27 94.8 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase family A RNase_T PF00929.19 CAM66410.1 - 8.5e-16 58.6 0.0 2.6e-15 57.0 0.0 2.0 1 0 0 1 1 1 1 Exonuclease RNase_H_2 PF13482.1 CAM66410.1 - 0.02 14.7 0.0 0.096 12.4 0.0 2.2 2 0 0 2 2 2 0 RNase_H superfamily Pro_dh PF01619.13 CAM66410.1 - 0.026 13.5 0.2 0.33 9.9 0.2 2.5 2 0 0 2 2 2 0 Proline dehydrogenase Peptidase_M32 PF02074.10 CAM66411.1 - 7.4e-129 430.5 0.0 8.3e-129 430.4 0.0 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase SURF1 PF02104.10 CAM66413.1 - 1.6e-27 96.7 0.0 3.6e-27 95.6 0.0 1.6 1 0 0 1 1 1 1 SURF1 family DUF1471 PF07338.8 CAM66413.1 - 0.08 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) F_actin_bind PF08919.5 CAM66414.1 - 0.00048 19.8 0.1 0.00064 19.4 0.1 1.4 1 1 0 1 1 1 1 F-actin binding Troponin PF00992.15 CAM66414.1 - 0.0092 16.0 6.3 0.012 15.6 4.4 1.3 1 0 0 1 1 1 1 Troponin Exc PF07825.6 CAM66414.1 - 0.0096 15.6 0.0 0.059 13.1 0.0 2.0 2 0 0 2 2 2 1 Excisionase-like protein Atg14 PF10186.4 CAM66414.1 - 0.017 14.1 4.9 0.024 13.5 3.4 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CRF PF00473.12 CAM66414.1 - 0.04 14.0 4.1 0.12 12.4 2.8 1.9 1 0 0 1 1 1 0 Corticotropin-releasing factor family DUF972 PF06156.8 CAM66414.1 - 0.12 12.7 5.2 1.6 9.0 2.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Spc24 PF08286.6 CAM66414.1 - 0.23 11.1 2.8 0.27 10.9 2.0 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF3166 PF11365.3 CAM66414.1 - 0.37 11.2 7.4 0.65 10.4 4.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3166) TSC22 PF01166.13 CAM66414.1 - 1.5 8.8 7.3 1 9.3 2.3 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family Latarcin PF10279.4 CAM66414.1 - 1.7 8.9 5.2 2.8 8.1 3.6 1.4 1 1 0 1 1 1 0 Latarcin precursor Jnk-SapK_ap_N PF09744.4 CAM66414.1 - 2 8.3 8.9 31 4.5 6.1 1.9 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 IncA PF04156.9 CAM66414.1 - 4.4 6.8 7.7 5.6 6.5 5.3 1.3 1 0 0 1 1 1 0 IncA protein Kinesin PF00225.18 CAM66415.1 - 9.8e-89 297.3 0.0 1.5e-88 296.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain zf-TRAF PF02176.13 CAM66415.1 - 5.4e-13 49.1 57.5 5.8e-07 29.8 5.7 5.5 6 1 1 7 7 7 4 TRAF-type zinc finger zf-U11-48K PF05253.7 CAM66415.1 - 1.1 9.0 7.5 25 4.7 0.0 4.8 5 0 0 5 5 5 0 U11-48K-like CHHC zinc finger zf-Di19 PF05605.7 CAM66415.1 - 6.8 6.9 26.4 0.088 12.9 2.5 4.5 3 2 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding Herpes_UL35 PF04496.7 CAM66416.1 - 0.027 14.7 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL35 family cNMP_binding PF00027.24 CAM66418.1 - 3.2e-33 113.4 0.5 1.2e-18 66.7 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 CAM66418.1 - 0.0023 17.8 1.9 3.2 8.1 0.1 3.1 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.2 CAM66418.1 - 0.83 9.3 3.6 2.5 7.8 0.3 2.5 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CAM66418.1 - 0.86 9.8 3.1 23 5.5 0.2 2.9 2 0 0 2 2 2 0 Leucine Rich Repeat MOZ_SAS PF01853.13 CAM66419.1 - 9.8e-21 73.8 0.0 6.5e-11 41.8 0.0 2.6 3 0 0 3 3 3 2 MOZ/SAS family TPR_12 PF13424.1 CAM66420.1 - 4.1e-17 61.8 14.7 1.4e-08 34.5 0.2 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 CAM66420.1 - 1.1e-06 28.2 18.9 0.0061 16.4 0.1 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 CAM66420.1 - 3.8e-05 23.2 7.8 0.22 11.5 0.1 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 CAM66420.1 - 0.017 15.5 1.4 26 5.5 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 CAM66420.1 - 0.029 15.0 19.5 0.29 11.8 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 CAM66420.1 - 0.033 13.7 2.3 2.9 7.6 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 CAM66420.1 - 0.23 11.1 7.6 1.9 8.2 0.1 4.0 6 0 0 6 6 6 0 TPR repeat TPR_7 PF13176.1 CAM66420.1 - 6.8 6.7 8.3 66 3.6 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Reprolysin_3 PF13582.1 CAM66421.1 - 0.07 13.6 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Lipase_3 PF01764.20 CAM66422.1 - 4.8e-15 55.4 0.0 8.1e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.7 CAM66422.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Ras PF00071.17 CAM66423.1 - 7.1e-53 178.3 0.2 8.6e-53 178.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAM66423.1 - 2.1e-17 63.7 0.0 2.9e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAM66423.1 - 3.2e-13 49.2 0.0 4.2e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CAM66423.1 - 7.9e-09 34.9 0.0 1e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CAM66423.1 - 3.9e-06 26.7 0.0 5.8e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 CAM66423.1 - 0.00011 22.2 0.0 0.00018 21.5 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CAM66423.1 - 0.00028 21.0 0.0 0.00046 20.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 CAM66423.1 - 0.00033 19.8 0.0 0.00062 18.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 NACHT PF05729.7 CAM66423.1 - 0.0011 18.5 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_5 PF07728.9 CAM66423.1 - 0.0061 16.2 0.0 0.012 15.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) G-alpha PF00503.15 CAM66423.1 - 0.0094 14.6 0.6 0.094 11.3 0.1 2.0 1 1 1 2 2 2 1 G-protein alpha subunit PRK PF00485.13 CAM66423.1 - 0.011 15.2 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family SRPRB PF09439.5 CAM66423.1 - 0.02 14.1 0.0 0.027 13.7 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit RNA_helicase PF00910.17 CAM66423.1 - 0.022 14.9 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase FeoB_N PF02421.13 CAM66423.1 - 0.025 13.8 0.0 0.23 10.7 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_18 PF13238.1 CAM66423.1 - 0.04 14.2 0.0 0.058 13.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.8 CAM66423.1 - 0.041 12.8 0.2 0.071 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.1 CAM66423.1 - 0.041 13.7 0.0 0.068 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 CAM66423.1 - 0.044 13.3 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 CAM66423.1 - 0.045 13.7 0.0 0.097 12.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DAP3 PF10236.4 CAM66423.1 - 0.052 12.4 0.1 0.096 11.6 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Sigma54_activat PF00158.21 CAM66423.1 - 0.054 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.1 CAM66423.1 - 0.063 12.8 0.2 0.15 11.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_32 PF13654.1 CAM66423.1 - 0.067 11.8 0.1 0.16 10.6 0.0 1.5 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 CAM66423.1 - 0.068 13.4 0.1 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 ABC transporter VirE PF05272.6 CAM66423.1 - 0.074 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Virulence-associated protein E ATP_bind_1 PF03029.12 CAM66423.1 - 0.074 12.5 0.1 0.23 10.9 0.0 1.7 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Rad17 PF03215.10 CAM66423.1 - 0.076 11.6 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Septin PF00735.13 CAM66423.1 - 0.085 11.8 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Septin Torsin PF06309.6 CAM66423.1 - 0.093 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA_17 PF13207.1 CAM66423.1 - 0.15 12.9 0.0 0.27 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain zf-RING_5 PF14634.1 CAM66424.1 - 3.6e-06 26.5 9.7 7.1e-06 25.6 6.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CAM66424.1 - 6e-06 25.8 9.1 1.2e-05 24.8 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CENP-F_leu_zip PF10473.4 CAM66424.1 - 0.0044 16.8 1.6 0.006 16.4 1.1 1.1 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-C3HC4_2 PF13923.1 CAM66424.1 - 0.0082 16.1 11.0 0.015 15.3 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) HAUS-augmin3 PF14932.1 CAM66424.1 - 0.0088 15.2 7.2 0.012 14.7 5.0 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 DUF1848 PF08902.6 CAM66424.1 - 0.014 14.9 0.4 0.018 14.6 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) zf-C3HC4 PF00097.20 CAM66424.1 - 0.014 14.9 9.0 0.028 14.0 6.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) IncA PF04156.9 CAM66424.1 - 0.017 14.7 5.4 0.026 14.1 3.7 1.2 1 0 0 1 1 1 0 IncA protein Allexi_40kDa PF05549.6 CAM66424.1 - 0.019 14.2 1.9 0.029 13.6 1.3 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF972 PF06156.8 CAM66424.1 - 0.035 14.4 1.1 0.067 13.5 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) zf-RING_6 PF14835.1 CAM66424.1 - 0.073 12.8 6.4 0.067 12.9 2.3 2.4 2 1 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 CAM66424.1 - 0.11 12.0 8.8 0.21 11.1 6.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.9 CAM66424.1 - 0.11 11.9 8.9 0.22 11.0 6.2 1.4 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_2 PF13639.1 CAM66424.1 - 0.2 11.5 14.8 0.039 13.7 7.4 2.0 2 1 1 3 3 2 0 Ring finger domain LCD1 PF09798.4 CAM66424.1 - 0.29 9.0 0.8 0.37 8.7 0.6 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF3839 PF12943.2 CAM66424.1 - 0.3 10.2 0.6 0.42 9.7 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3839) APG6 PF04111.7 CAM66424.1 - 0.34 9.9 3.1 0.47 9.4 2.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 CAM66424.1 - 0.45 9.4 10.3 0.7 8.7 7.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4164 PF13747.1 CAM66424.1 - 0.49 10.5 4.4 0.78 9.9 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) ADIP PF11559.3 CAM66424.1 - 0.56 10.1 6.7 0.89 9.4 4.7 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding 7tm_7 PF08395.7 CAM66424.1 - 1.5 7.8 3.4 2 7.3 2.4 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor DUF3138 PF11336.3 CAM66424.1 - 2.4 6.2 6.0 4.5 5.3 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Mnd1 PF03962.10 CAM66424.1 - 3.3 7.3 7.8 4.8 6.8 5.4 1.2 1 0 0 1 1 1 0 Mnd1 family Prok-RING_4 PF14447.1 CAM66424.1 - 4.8 6.8 8.2 14 5.2 5.7 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF4200 PF13863.1 CAM66425.1 - 5.5e-29 100.6 25.3 5.5e-29 100.6 17.5 3.3 3 1 0 3 3 3 1 Domain of unknown function (DUF4200) HTH_26 PF13443.1 CAM66425.1 - 0.019 15.1 2.5 0.21 11.8 0.5 2.6 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain Bromodomain PF00439.20 CAM66425.1 - 0.25 11.2 0.1 0.25 11.2 0.1 2.5 3 1 1 4 4 4 0 Bromodomain HSBP1 PF06825.7 CAM66425.1 - 0.94 9.0 7.4 4.1 7.0 1.0 2.9 2 1 0 2 2 2 0 Heat shock factor binding protein 1 DASH_Spc34 PF08657.5 CAM66425.1 - 4.4 6.8 21.1 0.62 9.6 0.5 2.6 2 1 0 2 2 2 0 DASH complex subunit Spc34 Lipase_3 PF01764.20 CAM66426.1 - 2.2e-13 50.0 0.0 3.7e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.7 CAM66426.1 - 0.23 11.1 0.0 0.38 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Tubulin PF00091.20 CAM66427.1 - 9.3e-39 133.4 0.0 1.4e-38 132.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Nipped-B_C PF12830.2 CAM66429.2 - 1e-34 119.8 0.0 3.7e-34 118.0 0.0 2.1 1 1 0 1 1 1 1 Sister chromatid cohesion C-terminus PBP1_TM PF14812.1 CAM66429.2 - 1.3 9.4 2.3 2.8 8.3 1.6 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AMP-binding PF00501.23 CAM66431.1 - 2.9e-56 190.6 0.3 2.9e-56 190.6 0.2 1.4 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.1 CAM66431.1 - 0.0013 19.6 0.3 0.0063 17.4 0.2 2.3 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain FeoA PF04023.9 CAM66431.1 - 0.086 12.8 0.0 0.39 10.7 0.0 2.0 2 0 0 2 2 2 0 FeoA domain Radial_spoke PF04712.7 CAM66432.1 - 8.3e-151 503.0 18.6 2e-113 379.7 4.6 2.0 1 1 1 2 2 2 2 Radial spokehead-like protein Pkinase PF00069.20 CAM66433.1 - 1.9e-82 276.3 0.0 3.7e-82 275.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM66433.1 - 9.1e-46 156.0 0.0 1.8e-45 155.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 CAM66433.1 - 4.9e-11 42.7 0.1 0.00018 21.6 0.1 3.6 2 1 1 3 3 3 2 HEAT repeats Arm PF00514.18 CAM66433.1 - 5.1e-10 38.7 5.8 0.00025 20.7 0.0 6.3 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 CAM66433.1 - 2.4e-09 37.3 4.5 0.005 17.2 0.1 5.4 4 1 1 5 5 4 3 HEAT-like repeat Kinase-like PF14531.1 CAM66433.1 - 3.2e-06 26.3 0.0 1.7e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 Kinase-like HEAT PF02985.17 CAM66433.1 - 3.4e-06 26.6 3.0 1.5 9.0 0.0 5.4 5 0 0 5 5 5 2 HEAT repeat RIO1 PF01163.17 CAM66433.1 - 0.00014 21.2 1.1 0.0016 17.8 0.4 2.2 1 1 1 2 2 2 1 RIO1 family YrbL-PhoP_reg PF10707.4 CAM66433.1 - 0.00081 18.7 0.1 0.0015 17.8 0.1 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 CAM66433.1 - 0.0039 16.9 0.0 0.041 13.6 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CAM66433.1 - 0.012 14.4 0.0 0.027 13.3 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 CAM66433.1 - 0.014 14.4 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cnd1 PF12717.2 CAM66433.1 - 0.014 15.2 0.7 0.17 11.7 0.0 2.9 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.4 CAM66433.1 - 0.027 12.7 0.8 0.089 11.0 0.0 2.1 2 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit DUF3361 PF11841.3 CAM66433.1 - 0.034 13.8 0.1 3.4 7.3 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.3 CAM66433.1 - 0.068 13.0 0.0 4.8 7.1 0.0 2.9 2 0 0 2 2 2 0 V-ATPase subunit H Alba PF01918.16 CAM66434.1 - 1.1e-13 50.5 0.4 1.1e-13 50.5 0.3 1.5 2 0 0 2 2 2 1 Alba Rpp20 PF12328.3 CAM66434.1 - 0.011 15.3 2.4 0.016 14.8 1.7 1.4 1 1 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P Acetyltransf_1 PF00583.19 CAM66435.1 - 3.2e-15 55.9 0.1 7.3e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CAM66435.1 - 3.2e-07 30.0 0.0 5.3e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 CAM66435.1 - 4.9e-05 23.4 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CAM66435.1 - 0.0013 18.7 0.1 0.0018 18.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CAM66435.1 - 0.0015 18.4 0.2 0.0022 17.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CAM66435.1 - 0.0097 16.0 0.1 0.022 14.8 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CAM66435.1 - 0.015 15.1 0.6 0.025 14.4 0.1 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CAM66435.1 - 0.022 14.9 0.0 0.031 14.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain C2 PF00168.25 CAM66441.1 - 0.00055 19.7 0.0 0.003 17.3 0.0 2.1 2 0 0 2 2 2 1 C2 domain RNA_pol_N PF01194.12 CAM66441.1 - 0.068 13.1 0.1 0.22 11.5 0.1 1.8 2 0 0 2 2 2 0 RNA polymerases N / 8 kDa subunit ATXN-1_C PF12547.3 CAM66442.1 - 0.021 14.7 0.9 0.067 13.1 0.6 1.8 1 0 0 1 1 1 0 Capicua transcriptional repressor modulator TMF_TATA_bd PF12325.3 CAM66443.1 - 1.4e-06 28.0 2.3 1.4e-06 28.0 1.6 5.3 3 1 2 5 5 5 3 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.4 CAM66443.1 - 1.3e-05 25.1 55.9 0.13 12.0 0.7 6.0 2 1 2 6 6 6 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 CAM66443.1 - 0.0004 19.9 57.2 0.00067 19.2 27.7 4.6 1 1 2 3 3 3 1 Intermediate filament protein GAS PF13851.1 CAM66443.1 - 0.00072 18.8 50.6 0.15 11.2 0.7 4.4 2 1 1 4 4 4 3 Growth-arrest specific micro-tubule binding Rootletin PF15035.1 CAM66443.1 - 0.0012 18.9 61.7 0.14 12.1 6.6 5.4 1 1 3 4 4 4 3 Ciliary rootlet component, centrosome cohesion LPP PF04728.8 CAM66443.1 - 0.0013 18.4 6.9 0.39 10.5 0.6 4.9 5 0 0 5 5 5 1 Lipoprotein leucine-zipper Atg14 PF10186.4 CAM66443.1 - 0.0062 15.5 12.0 0.0062 15.5 8.3 3.8 2 1 2 4 4 4 2 UV radiation resistance protein and autophagy-related subunit 14 MscS_porin PF12795.2 CAM66443.1 - 0.0069 15.7 13.8 0.0069 15.7 9.5 4.7 2 1 2 4 4 3 1 Mechanosensitive ion channel porin domain FlaC_arch PF05377.6 CAM66443.1 - 0.012 15.4 26.5 0.58 10.1 0.2 7.3 6 2 2 8 8 7 0 Flagella accessory protein C (FlaC) Reo_sigmaC PF04582.7 CAM66443.1 - 0.015 14.4 23.7 0.053 12.6 2.5 3.1 1 1 1 3 3 3 0 Reovirus sigma C capsid protein Fib_alpha PF08702.5 CAM66443.1 - 0.016 15.3 30.3 0.36 10.9 3.3 4.1 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family HALZ PF02183.13 CAM66443.1 - 0.017 14.8 29.0 2 8.1 0.1 7.4 6 1 0 6 6 6 0 Homeobox associated leucine zipper DivIC PF04977.10 CAM66443.1 - 0.023 14.1 0.3 0.023 14.1 0.2 8.2 3 2 4 7 7 7 0 Septum formation initiator THP2 PF09432.5 CAM66443.1 - 0.031 14.1 14.1 0.1 12.4 0.9 3.7 3 0 0 3 3 3 0 Tho complex subunit THP2 IncA PF04156.9 CAM66443.1 - 0.052 13.1 64.6 0.17 11.4 1.6 5.1 2 1 1 4 4 4 0 IncA protein Med9 PF07544.8 CAM66443.1 - 0.062 13.0 0.4 0.062 13.0 0.3 6.1 4 2 1 5 5 4 0 RNA polymerase II transcription mediator complex subunit 9 Myosin_tail_1 PF01576.14 CAM66443.1 - 0.067 10.9 58.6 0.014 13.1 20.5 3.5 2 1 1 3 3 3 0 Myosin tail Baculo_PEP_C PF04513.7 CAM66443.1 - 0.14 11.9 25.7 0.22 11.3 1.2 4.2 1 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus FAA_hydrolase_N PF09298.6 CAM66443.1 - 0.15 12.1 0.0 0.15 12.1 0.0 4.0 2 1 1 4 4 4 0 Fumarylacetoacetase N-terminal DUF1664 PF07889.7 CAM66443.1 - 0.18 11.5 25.0 5.4 6.8 0.1 5.2 2 1 1 5 5 5 0 Protein of unknown function (DUF1664) ATG16 PF08614.6 CAM66443.1 - 0.23 11.2 58.6 0.77 9.5 11.4 5.2 2 2 0 4 4 4 0 Autophagy protein 16 (ATG16) EzrA PF06160.7 CAM66443.1 - 0.48 8.5 42.1 7.4 4.6 25.9 4.1 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA Mnd1 PF03962.10 CAM66443.1 - 0.49 10.0 51.5 1.1 8.8 2.9 5.4 2 1 4 6 6 6 0 Mnd1 family Seryl_tRNA_N PF02403.17 CAM66443.1 - 0.52 10.3 43.0 0.54 10.3 0.4 6.2 3 2 4 7 7 7 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.7 CAM66443.1 - 0.61 10.3 23.2 2.7 8.2 1.6 5.5 4 2 1 5 5 4 0 Nucleopolyhedrovirus P10 protein DUF1045 PF06299.7 CAM66443.1 - 0.9 9.1 10.2 0.22 11.1 0.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1045) TMF_DNA_bd PF12329.3 CAM66443.1 - 2 8.2 58.6 0.19 11.5 2.1 7.9 4 3 4 8 8 8 0 TATA element modulatory factor 1 DNA binding DUF342 PF03961.8 CAM66443.1 - 3.3 6.0 35.3 0.96 7.7 5.0 4.5 2 1 3 5 5 5 0 Protein of unknown function (DUF342) Nbl1_Borealin_N PF10444.4 CAM66443.1 - 8.1 5.8 12.0 1.9 7.8 0.2 4.9 5 1 1 6 6 5 0 Nbl1 / Borealin N terminal His_Phos_1 PF00300.17 CAM66444.1 - 7.9e-10 39.0 0.0 2e-09 37.7 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Sec63 PF02889.11 CAM66445.1 - 1.9e-154 513.5 2.5 4.5e-91 305.3 0.5 2.8 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.24 CAM66445.1 - 2.3e-53 180.1 0.0 2e-28 98.9 0.1 2.8 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 CAM66445.1 - 5.6e-22 78.4 0.0 9.6e-13 48.3 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CAM66445.1 - 1.7e-16 59.8 0.0 1e-07 31.7 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_10 PF12846.2 CAM66445.1 - 5e-05 22.8 0.7 1.6 8.1 0.0 4.4 4 1 0 5 5 5 1 AAA-like domain AAA_19 PF13245.1 CAM66445.1 - 8.7e-05 22.1 0.0 0.11 12.3 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain AAA_22 PF13401.1 CAM66445.1 - 0.00023 21.3 0.1 0.21 11.7 0.1 3.7 2 2 0 2 2 2 1 AAA domain PhoH PF02562.11 CAM66445.1 - 0.0012 18.1 0.1 0.091 11.9 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein T2SE PF00437.15 CAM66445.1 - 0.0013 17.6 0.0 1.9 7.2 0.0 2.8 3 0 0 3 3 3 2 Type II/IV secretion system protein DUF2075 PF09848.4 CAM66445.1 - 0.023 13.7 0.0 0.07 12.0 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 CAM66445.1 - 0.073 12.4 0.0 16 4.8 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein DUF1014 PF06244.7 CAM66447.1 - 1.4e-15 57.5 13.0 5.5e-14 52.4 9.0 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) Selenoprotein_S PF06936.6 CAM66447.1 - 0.014 14.9 12.5 0.1 12.1 8.7 2.2 2 0 0 2 2 2 0 Selenoprotein S (SelS) F-protein PF00469.15 CAM66447.1 - 0.12 11.7 6.3 0.23 10.8 4.4 1.4 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef DUF4355 PF14265.1 CAM66447.1 - 0.13 12.2 22.2 0.29 11.0 15.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) DUF3435 PF11917.3 CAM66447.1 - 0.72 8.5 11.7 1 8.0 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) DUF3464 PF11947.3 CAM66447.1 - 6.4 6.2 8.4 12 5.3 5.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) RTX_C PF08339.5 CAM66448.1 - 2.6 7.7 5.3 6.5 6.4 3.7 1.6 1 0 0 1 1 1 0 RTX C-terminal domain DUF179 PF02622.10 CAM66450.1 - 1.8e-26 92.7 0.0 3.1e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 Ribosomal_L18e PF00828.14 CAM66451.1 - 1.6e-20 73.7 0.2 1.6e-20 73.7 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 Ribosomal_L7Ae PF01248.21 CAM66452.1 - 8.3e-23 79.7 1.4 1.1e-22 79.3 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Msg2_C PF12373.3 CAM66452.1 - 0.053 12.7 0.2 0.15 11.2 0.1 1.8 1 0 0 1 1 1 0 Major surface glycoprotein 2 C terminal Phage_NinH PF06322.6 CAM66452.1 - 0.071 12.7 0.6 6.6 6.4 0.0 2.3 2 0 0 2 2 2 0 Phage NinH protein DUF607 PF04678.8 CAM66455.1 - 7.7e-16 58.5 0.2 9.7e-16 58.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF607 DUF1192 PF06698.6 CAM66455.1 - 0.13 12.1 0.2 0.13 12.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Acetyltransf_1 PF00583.19 CAM66456.1 - 7.2e-06 25.9 0.1 1.3e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CAM66456.1 - 0.03 14.4 0.0 0.054 13.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.1 CAM66456.1 - 0.085 13.4 0.1 7.6 7.1 0.0 2.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain APG6 PF04111.7 CAM66457.1 - 0.059 12.4 4.0 0.09 11.8 2.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 NAD_binding_7 PF13241.1 CAM66457.1 - 0.64 10.2 4.4 17 5.7 0.5 2.3 1 1 0 2 2 2 0 Putative NAD(P)-binding HAUS6_N PF14661.1 CAM66457.1 - 1.2 8.4 5.2 2.4 7.4 3.6 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus FadA PF09403.5 CAM66457.1 - 7 6.6 11.4 2.8 7.9 2.6 2.9 2 1 1 3 3 3 0 Adhesion protein FadA Cse1 PF08506.5 CAM66459.1 - 0.0026 16.3 0.0 0.0066 15.0 0.0 1.6 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 CAM66459.1 - 0.0033 17.3 0.1 0.21 11.5 0.0 3.3 2 1 0 2 2 2 1 Importin-beta N-terminal domain SDA1 PF05285.7 CAM66459.1 - 0.0044 16.3 12.8 0.0068 15.7 8.9 1.2 1 0 0 1 1 1 1 SDA1 Xpo1 PF08389.7 CAM66459.1 - 0.022 14.6 0.1 0.31 10.9 0.0 2.5 2 0 0 2 2 2 0 Exportin 1-like protein HEAT PF02985.17 CAM66459.1 - 0.038 14.0 2.0 0.29 11.3 0.3 3.6 2 0 0 2 2 2 0 HEAT repeat Daxx PF03344.10 CAM66459.1 - 3.1 6.1 10.5 4.8 5.5 7.3 1.2 1 0 0 1 1 1 0 Daxx Family zf-DHHC PF01529.15 CAM66460.1 - 3.6e-38 130.6 0.0 1.4e-37 128.7 0.0 1.8 1 1 1 2 2 2 1 DHHC palmitoyltransferase U-box PF04564.10 CAM66461.2 - 1.8e-06 27.8 0.0 4.1e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 U-box domain Fe_dep_repr_C PF02742.10 CAM66461.2 - 0.13 11.9 0.4 0.3 10.7 0.3 1.6 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain Lectin_leg-like PF03388.8 CAM66462.1 - 7.6e-47 159.3 0.0 1.5e-46 158.4 0.0 1.4 1 0 0 1 1 1 1 Legume-like lectin family PAT1 PF09770.4 CAM66462.1 - 0.039 12.2 39.2 0.05 11.8 27.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 V_ATPase_I PF01496.14 CAM66462.1 - 0.094 10.5 11.9 0.11 10.3 8.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TFIIA PF03153.8 CAM66462.1 - 0.46 10.3 29.3 0.63 9.8 20.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pox_A_type_inc PF04508.7 CAM66462.1 - 1.3 8.9 8.3 0.23 11.3 2.9 2.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat CRT10 PF08728.5 CAM66462.1 - 1.3 6.9 9.9 1.8 6.4 6.8 1.1 1 0 0 1 1 1 0 CRT10 GAGA_bind PF06217.7 CAM66462.1 - 1.9 8.3 17.0 2.7 7.8 11.8 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DUF605 PF04652.11 CAM66462.1 - 8 5.7 29.4 12 5.1 20.4 1.2 1 0 0 1 1 1 0 Vta1 like Peptidase_M24 PF00557.19 CAM66463.1 - 2.7e-22 79.3 1.0 1.4e-21 77.0 0.7 2.3 1 1 0 1 1 1 1 Metallopeptidase family M24 PSP1 PF04468.7 CAM66464.1 - 1.4e-24 85.9 0.0 3e-24 84.7 0.0 1.6 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Kinesin PF00225.18 CAM66465.1 - 4.5e-33 114.3 0.0 2.8e-06 26.2 0.0 5.2 5 0 0 5 5 5 5 Kinesin motor domain ArfGap PF01412.13 CAM66466.1 - 8.3e-29 99.7 0.1 1.4e-28 98.9 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf ADH_zinc_N PF00107.21 CAM66467.1 - 2.9e-17 62.4 0.0 5.2e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CAM66467.1 - 3.7e-13 49.1 0.0 1.1e-12 47.6 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ubiquitin PF00240.18 CAM66468.1 - 1.2e-09 37.4 0.0 2.5e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CAM66468.1 - 2.3e-05 23.9 0.0 4.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 CAM66468.1 - 0.0018 18.1 0.0 0.011 15.6 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CAM66468.1 - 0.003 17.7 0.0 0.0089 16.1 0.0 1.8 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.1 CAM66468.1 - 0.1 12.8 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain Pox_RNA_Pol_19 PF05320.7 CAM66468.1 - 0.18 11.5 0.1 0.46 10.2 0.1 1.7 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF4085 PF13315.1 CAM66468.1 - 0.28 10.5 0.2 6.3 6.1 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4085) Anoctamin PF04547.7 CAM66469.1 - 3.9e-100 335.6 0.0 4.7e-100 335.3 0.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel IPP-2 PF04979.9 CAM66470.1 - 0.1 12.8 1.0 0.18 12.0 0.7 1.4 1 0 0 1 1 1 0 Protein phosphatase inhibitor 2 (IPP-2) C2 PF00168.25 CAM66471.2 - 9.7e-17 60.6 0.0 2.4e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 C2 domain YbjQ_1 PF01906.12 CAM66471.2 - 0.00013 22.3 0.0 0.41 11.1 0.0 4.1 4 0 0 4 4 4 1 Putative heavy-metal-binding DSPc PF00782.15 CAM66472.2 - 3.5e-08 33.1 0.1 7.4e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CAM66472.2 - 0.13 11.6 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Pkinase PF00069.20 CAM66473.1 - 2.9e-40 138.0 0.0 8.3e-34 116.9 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAM66473.1 - 7.1e-16 58.0 0.0 8.9e-15 54.4 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM66473.1 - 0.008 15.1 0.0 0.019 13.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like DUF2392 PF10288.4 CAM66474.1 - 2.3e-05 24.6 0.0 3.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) CDRN PF05174.7 CAM66474.1 - 0.027 13.9 0.3 0.13 11.6 0.0 2.4 2 0 0 2 2 2 0 Cysteine-rich D. radiodurans N terminus ATP_bind_3 PF01171.15 CAM66474.1 - 0.055 12.9 0.0 0.42 10.0 0.0 2.2 2 0 0 2 2 2 0 PP-loop family HCV_NS5a_C PF12941.2 CAM66475.1 - 4.6 6.7 11.9 0.34 10.4 4.3 1.9 2 0 0 2 2 2 0 HCV NS5a protein C-terminal region Complex1_LYR_2 PF13233.1 CAM66477.1 - 1e-06 29.1 0.1 1.9e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 Complex1_LYR-like IncA PF04156.9 CAM66478.1 - 5.9 6.4 14.2 0.57 9.7 0.5 2.9 2 0 0 2 2 2 0 IncA protein Peptidase_M16 PF00675.15 CAM66482.1 - 3.7e-07 29.9 0.4 0.01 15.5 0.0 2.6 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CAM66482.1 - 1.1e-06 28.4 0.0 3.6e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain OEP PF02321.13 CAM66484.1 - 0.13 11.8 7.6 18 4.8 0.0 2.2 2 0 0 2 2 2 0 Outer membrane efflux protein LRR_6 PF13516.1 CAM66486.1 - 2e-05 24.1 3.1 0.24 11.5 0.0 3.8 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.2 CAM66486.1 - 0.00036 20.0 4.8 0.00036 20.0 3.3 2.1 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CAM66486.1 - 0.0044 16.8 5.1 0.29 11.3 0.4 3.0 2 0 0 2 2 2 2 Leucine Rich Repeat LRR_7 PF13504.1 CAM66486.1 - 0.015 15.3 2.2 1.7 9.2 0.1 3.1 2 0 0 2 2 2 0 Leucine rich repeat LRR_8 PF13855.1 CAM66486.1 - 0.028 14.1 4.1 0.18 11.5 0.5 2.7 1 1 2 3 3 3 0 Leucine rich repeat Ax_dynein_light PF10211.4 CAM66487.1 - 6.7e-06 26.0 4.4 6.7e-06 26.0 3.0 2.2 2 0 0 2 2 2 1 Axonemal dynein light chain LRR19-TM PF15176.1 CAM66487.1 - 0.017 14.7 0.2 0.061 13.0 0.1 1.9 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain GvpG PF05120.7 CAM66487.1 - 0.12 12.2 2.5 0.38 10.5 1.7 1.8 1 0 0 1 1 1 0 Gas vesicle protein G DUF2009 PF09418.5 CAM66487.1 - 0.33 9.6 0.9 0.61 8.7 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) Spc24 PF08286.6 CAM66487.1 - 0.43 10.2 2.4 1.2 8.8 1.7 1.8 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF4557 PF15101.1 CAM66487.1 - 4.1 7.1 7.2 0.26 11.1 1.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Glyco_transf_25 PF01755.12 CAM66488.1 - 2.5e-19 69.7 0.0 1.1e-18 67.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) TRM PF02005.11 CAM66489.1 - 4.8e-94 315.3 0.0 4.2e-44 151.0 0.1 3.1 3 0 0 3 3 3 3 N2,N2-dimethylguanosine tRNA methyltransferase DDRGK PF09756.4 CAM66489.1 - 0.49 9.7 7.7 0.72 9.2 5.3 1.2 1 0 0 1 1 1 0 DDRGK domain Actin PF00022.14 CAM66490.1 - 1.2e-112 376.2 0.0 7.6e-111 370.3 0.0 2.0 1 1 0 1 1 1 1 Actin RAP1 PF07218.6 CAM66490.1 - 0.57 8.2 1.0 0.79 7.7 0.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AAA PF00004.24 CAM66491.2 - 2.1e-37 128.2 0.0 4e-37 127.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 CAM66491.2 - 9.8e-07 28.5 0.0 2.7e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 CAM66491.2 - 4.8e-06 26.7 0.9 0.00027 21.0 0.1 3.0 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CAM66491.2 - 1.4e-05 24.2 0.0 2.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 CAM66491.2 - 0.00014 21.3 0.3 0.15 11.4 0.2 2.4 1 1 1 2 2 2 2 AAA domain TIP49 PF06068.8 CAM66491.2 - 0.00088 18.0 0.0 0.0014 17.4 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 CAM66491.2 - 0.001 18.7 0.2 0.005 16.5 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 CAM66491.2 - 0.0011 19.0 1.6 0.013 15.4 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.12 CAM66491.2 - 0.0014 18.1 0.1 0.0029 17.0 0.1 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 CAM66491.2 - 0.0017 18.6 0.0 0.0057 16.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.9 CAM66491.2 - 0.0053 16.4 0.0 0.013 15.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CAM66491.2 - 0.0053 17.5 0.0 0.012 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 CAM66491.2 - 0.0099 15.7 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 CAM66491.2 - 0.011 14.9 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 CAM66491.2 - 0.016 15.0 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 CAM66491.2 - 0.018 14.1 0.1 0.56 9.2 0.0 2.2 1 1 1 2 2 2 0 KaiC AAA_24 PF13479.1 CAM66491.2 - 0.021 14.4 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CAM66491.2 - 0.028 14.3 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 CAM66491.2 - 0.028 13.6 0.2 0.096 11.9 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.17 CAM66491.2 - 0.03 14.4 0.0 0.065 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.1 CAM66491.2 - 0.033 14.1 0.0 0.081 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain LisH PF08513.6 CAM66491.2 - 0.037 13.7 0.0 0.093 12.5 0.0 1.7 1 0 0 1 1 1 0 LisH Mesothelin PF06060.7 CAM66491.2 - 0.081 10.9 0.1 0.13 10.2 0.0 1.2 1 0 0 1 1 1 0 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) K-cyclin_vir_C PF09080.5 CAM66492.1 - 0.041 14.0 3.9 4.9 7.3 0.0 3.1 3 0 0 3 3 3 0 K cyclin, C terminal A_deaminase PF00962.17 CAM66493.2 - 4.1e-76 256.0 0.0 9.6e-72 241.6 0.0 2.7 2 1 0 2 2 2 2 Adenosine/AMP deaminase Casein PF00363.13 CAM66494.1 - 0.14 12.8 1.3 0.27 11.8 0.9 1.4 1 0 0 1 1 1 0 Casein BRCA2 PF00634.13 CAM66495.1 - 0.034 13.4 0.3 0.078 12.2 0.2 1.6 1 0 0 1 1 1 0 BRCA2 repeat CAP59_mtransfer PF11735.3 CAM66497.1 - 2.7e-78 262.5 0.0 4.1e-77 258.6 0.0 2.2 2 0 0 2 2 2 1 Cryptococcal mannosyltransferase 1 Peptidase_S8 PF00082.17 CAM66499.2 - 3.8e-22 78.7 0.3 7.5e-22 77.7 0.2 1.4 1 0 0 1 1 1 1 Subtilase family Dpy-30 PF05186.8 CAM66500.1 - 2.5e-08 33.2 0.5 4.4e-08 32.4 0.3 1.4 1 0 0 1 1 1 1 Dpy-30 motif NAD_binding_1 PF00175.16 CAM66501.1 - 5.8e-28 97.6 0.0 5.6e-27 94.4 0.0 2.3 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CAM66501.1 - 1e-27 96.1 0.1 1.4e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 CAM66501.1 - 0.00083 19.2 0.0 0.02 14.8 0.0 2.3 1 1 0 2 2 2 1 Ferric reductase NAD binding domain AAA PF00004.24 CAM66504.1 - 1.4e-42 145.0 0.0 2.4e-42 144.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CAM66504.1 - 1.9e-06 28.0 0.2 0.00032 20.8 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CAM66504.1 - 2.6e-06 27.2 0.1 8.9e-06 25.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CAM66504.1 - 2.7e-06 27.3 0.0 5.5e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CAM66504.1 - 3.5e-05 23.8 0.1 0.0014 18.6 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 CAM66504.1 - 0.00048 20.9 0.3 0.002 18.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 CAM66504.1 - 0.00053 18.9 0.0 0.00083 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 CAM66504.1 - 0.0015 17.6 0.0 0.0027 16.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CAM66504.1 - 0.0036 17.0 0.4 0.0087 15.7 0.3 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 CAM66504.1 - 0.0049 17.1 0.1 0.011 16.0 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CAM66504.1 - 0.0053 16.6 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CAM66504.1 - 0.0058 16.5 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 CAM66504.1 - 0.0076 15.8 0.0 0.019 14.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CAM66504.1 - 0.017 15.1 0.1 0.039 13.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.12 CAM66504.1 - 0.021 14.2 0.1 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.17 CAM66504.1 - 0.021 14.9 0.0 0.059 13.5 0.0 1.8 2 0 0 2 2 1 0 RNA helicase KaiC PF06745.8 CAM66504.1 - 0.029 13.5 0.3 0.26 10.3 0.1 2.1 1 1 1 2 2 2 0 KaiC NACHT PF05729.7 CAM66504.1 - 0.029 14.0 0.1 0.69 9.5 0.1 2.4 1 1 1 2 2 2 0 NACHT domain Zeta_toxin PF06414.7 CAM66504.1 - 0.034 13.2 0.0 0.067 12.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 CAM66504.1 - 0.034 13.5 0.6 1.9 7.8 0.1 2.4 1 1 1 2 2 2 0 AAA domain NB-ARC PF00931.17 CAM66504.1 - 0.047 12.5 0.0 0.093 11.5 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.4 CAM66504.1 - 0.056 12.4 0.0 0.098 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.1 CAM66504.1 - 0.069 12.7 1.2 0.33 10.5 0.1 2.6 4 0 0 4 4 4 0 AAA domain TIP49 PF06068.8 CAM66504.1 - 0.081 11.6 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 CAM66504.1 - 0.089 11.9 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI tRNA-synt_1 PF00133.17 CAM66505.1 - 3.6e-28 97.9 0.0 5e-10 38.0 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 CAM66505.1 - 1.6e-21 76.4 0.0 8.7e-11 41.0 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 CAM66505.1 - 1.1e-11 44.7 0.9 2.7e-11 43.4 0.1 2.1 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 CAM66505.1 - 2.8e-07 29.9 0.0 6.4e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain RNA_pol_N PF01194.12 CAM66507.1 - 3.5e-25 87.7 1.3 4.3e-25 87.5 0.9 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 CAM66507.1 - 0.21 11.6 1.1 0.42 10.7 0.7 1.5 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) DUF155 PF02582.9 CAM66508.1 - 1e-37 129.7 0.0 1.5e-37 129.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 CorA PF01544.13 CAM66508.1 - 0.14 11.2 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF1664 PF07889.7 CAM66508.1 - 0.17 11.7 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Abhydrolase_6 PF12697.2 CAM66509.1 - 1.7e-26 93.5 4.0 4.8e-25 88.7 2.7 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CAM66509.1 - 1.2e-09 38.0 3.6 8.9e-09 35.2 2.5 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAM66509.1 - 2.6e-09 36.9 0.0 0.00072 19.1 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Esterase PF00756.15 CAM66509.1 - 0.00048 19.6 0.0 0.0011 18.5 0.0 1.6 1 0 0 1 1 1 1 Putative esterase Abhydro_lipase PF04083.11 CAM66509.1 - 0.044 13.1 0.0 0.13 11.6 0.0 1.7 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region PGAP1 PF07819.8 CAM66509.1 - 0.07 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.9 CAM66509.1 - 0.16 11.2 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Endonuc-BglII PF09195.6 CAM66510.1 - 0.055 12.9 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease BglII EF-hand_7 PF13499.1 CAM66511.1 - 1.3e-15 57.2 0.1 1.1e-07 31.8 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CAM66511.1 - 5.5e-14 50.3 4.2 1.1e-07 30.6 0.0 3.8 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.1 CAM66511.1 - 1.7e-12 46.7 2.2 5e-05 22.8 0.0 3.7 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 CAM66511.1 - 3.2e-10 39.0 0.3 6.4e-06 25.6 0.0 3.8 2 1 2 4 4 4 2 EF-hand domain EF-hand_5 PF13202.1 CAM66511.1 - 2.9e-08 32.6 0.4 2.2e-05 23.5 0.1 3.4 2 1 1 3 3 3 1 EF hand EF-hand_9 PF14658.1 CAM66511.1 - 0.0009 19.1 0.0 0.8 9.6 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain PNRC PF15365.1 CAM66511.1 - 0.022 14.7 1.7 0.056 13.4 1.2 1.8 1 1 0 1 1 1 0 Proline-rich nuclear receptor coactivator EF-hand_4 PF12763.2 CAM66511.1 - 0.061 13.0 0.1 3.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand p25-alpha PF05517.7 CAM66511.1 - 0.14 12.4 0.3 17 5.6 0.0 2.8 2 1 1 3 3 3 0 p25-alpha MAM33 PF02330.11 CAM66512.1 - 0.0011 18.7 0.0 0.0017 18.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial glycoprotein Tctex-1 PF03645.8 CAM66513.1 - 7.1e-26 90.0 0.0 8.6e-26 89.7 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family QueF PF14489.1 CAM66513.1 - 0.066 13.1 0.0 0.14 12.1 0.0 1.5 2 0 0 2 2 2 0 QueF-like protein Rio2_N PF09202.6 CAM66513.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Rio2, N-terminal Adenylsucc_synt PF00709.16 CAM66514.1 - 1e-127 426.3 0.0 1.2e-127 426.0 0.0 1.1 1 0 0 1 1 1 1 Adenylosuccinate synthetase Ribosomal_L27 PF01016.14 CAM66515.1 - 0.042 13.6 0.0 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 Ribosomal L27 protein Nucleoside_tran PF01733.13 CAM66516.1 - 2.5e-29 102.4 1.2 1.5e-18 67.0 0.0 2.4 2 0 0 2 2 2 2 Nucleoside transporter Ribosomal_S4e PF00900.15 CAM66517.1 - 6e-25 86.7 0.1 1e-24 86.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 CAM66517.1 - 1e-18 66.9 3.4 2.3e-18 65.7 2.4 1.7 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 CAM66517.1 - 3.8e-06 26.2 0.0 9e-06 25.0 0.0 1.7 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 CAM66517.1 - 5e-05 22.8 0.3 0.00017 21.1 0.2 1.9 1 0 0 1 1 1 1 KOW motif Ribosomal_S4e PF00900.15 CAM66518.1 - 1.5e-24 85.4 0.1 2.6e-24 84.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 CAM66518.1 - 2.3e-18 65.7 4.4 4.9e-18 64.7 3.1 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 CAM66518.1 - 9.5e-06 24.9 0.0 2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 CAM66518.1 - 0.00014 21.4 0.3 0.00035 20.1 0.2 1.7 1 0 0 1 1 1 1 KOW motif TPK_B1_binding PF04265.9 CAM66519.1 - 3e-09 36.4 0.0 1.2e-08 34.5 0.0 1.9 2 0 0 2 2 2 1 Thiamin pyrophosphokinase, vitamin B1 binding domain TPK_catalytic PF04263.11 CAM66519.1 - 1.1e-07 31.4 0.0 0.026 14.0 0.0 3.3 3 0 0 3 3 3 2 Thiamin pyrophosphokinase, catalytic domain DUF624 PF04854.9 CAM66520.1 - 0.011 15.5 0.1 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF624 BatA PF07584.6 CAM66520.1 - 0.08 13.1 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal Herpes_gE PF02480.11 CAM66521.1 - 0.00031 19.1 0.0 0.0004 18.7 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF1510 PF07423.6 CAM66521.1 - 0.00089 18.6 0.2 0.0011 18.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) TMEM154 PF15102.1 CAM66521.1 - 0.009 15.7 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family DUF4381 PF14316.1 CAM66521.1 - 0.025 14.7 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Zip PF02535.17 CAM66521.1 - 0.033 13.1 0.3 0.045 12.7 0.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CRA PF06589.6 CAM66521.1 - 0.045 13.0 0.0 0.065 12.5 0.0 1.2 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) EphA2_TM PF14575.1 CAM66521.1 - 0.064 13.6 0.2 0.13 12.7 0.1 1.5 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Sarcoglycan_2 PF05510.8 CAM66521.1 - 0.07 11.4 0.0 0.087 11.1 0.0 1.1 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon TRAP_alpha PF03896.11 CAM66521.1 - 0.071 12.0 1.2 0.094 11.6 0.9 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Shisa PF13908.1 CAM66521.1 - 0.12 12.5 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF2946 PF11162.3 CAM66521.1 - 0.16 12.1 0.2 0.16 12.1 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) Endonuclease_NS PF01223.18 CAM66522.1 - 3.7e-16 59.3 0.0 6.7e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease ATP_bind_1 PF03029.12 CAM66523.1 - 4.2e-63 213.0 0.0 1.3e-62 211.4 0.0 1.7 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein SRP54 PF00448.17 CAM66523.1 - 4.8e-06 26.1 0.0 0.00097 18.6 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain CbiA PF01656.18 CAM66523.1 - 1.2e-05 24.8 0.0 1.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain GTP_EFTU PF00009.22 CAM66523.1 - 1.6e-05 24.4 0.0 0.00028 20.3 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 CAM66523.1 - 0.00011 22.2 0.0 0.00026 21.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain ArgK PF03308.11 CAM66523.1 - 0.0003 19.6 0.9 0.0068 15.2 0.1 3.0 2 2 0 2 2 2 1 ArgK protein MMR_HSR1 PF01926.18 CAM66523.1 - 0.00035 20.4 0.2 0.00073 19.4 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_19 PF13245.1 CAM66523.1 - 0.00048 19.8 0.7 0.0028 17.3 0.2 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_24 PF13479.1 CAM66523.1 - 0.00072 19.1 0.1 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 CAM66523.1 - 0.00086 19.0 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 CAM66523.1 - 0.00092 18.7 0.7 0.26 10.7 0.0 2.5 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 CAM66523.1 - 0.0023 17.5 0.8 0.0039 16.8 0.0 1.7 2 0 0 2 2 1 1 AAA domain Arf PF00025.16 CAM66523.1 - 0.0027 16.9 0.0 0.24 10.6 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family Zeta_toxin PF06414.7 CAM66523.1 - 0.0034 16.5 0.0 0.0068 15.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 CAM66523.1 - 0.0044 17.1 0.0 0.011 15.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain Miro PF08477.8 CAM66523.1 - 0.0047 17.4 0.5 0.13 12.7 0.3 2.4 1 1 0 1 1 1 1 Miro-like protein NACHT PF05729.7 CAM66523.1 - 0.0058 16.3 0.0 0.017 14.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain DLIC PF05783.6 CAM66523.1 - 0.0058 15.3 0.1 0.27 9.8 0.0 2.1 2 0 0 2 2 2 1 Dynein light intermediate chain (DLIC) AAA_33 PF13671.1 CAM66523.1 - 0.0059 16.4 0.0 0.0092 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 CAM66523.1 - 0.0073 15.2 0.1 0.013 14.3 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_17 PF13207.1 CAM66523.1 - 0.0081 16.9 0.1 0.017 15.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.5 CAM66523.1 - 0.013 14.7 0.1 0.82 8.8 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit 6PF2K PF01591.13 CAM66523.1 - 0.013 14.5 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DUF258 PF03193.11 CAM66523.1 - 0.018 14.2 0.0 0.32 10.1 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function, DUF258 Torsin PF06309.6 CAM66523.1 - 0.02 14.8 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Torsin NTPase_1 PF03266.10 CAM66523.1 - 0.021 14.5 0.2 0.091 12.4 0.2 2.0 1 1 0 1 1 1 0 NTPase G-alpha PF00503.15 CAM66523.1 - 0.042 12.5 0.0 1.5 7.4 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit MipZ PF09140.6 CAM66523.1 - 0.043 12.9 0.0 0.066 12.2 0.0 1.4 1 1 0 1 1 1 0 ATPase MipZ APS_kinase PF01583.15 CAM66523.1 - 0.043 13.4 0.1 0.097 12.3 0.0 1.6 2 0 0 2 2 1 0 Adenylylsulphate kinase Ras PF00071.17 CAM66523.1 - 0.045 13.1 0.3 3 7.2 0.0 2.7 3 1 0 3 3 2 0 Ras family Sigma54_activat PF00158.21 CAM66523.1 - 0.047 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain KAP_NTPase PF07693.9 CAM66523.1 - 0.047 12.6 0.0 0.047 12.6 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Arch_ATPase PF01637.13 CAM66523.1 - 0.048 13.3 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase IstB_IS21 PF01695.12 CAM66523.1 - 0.048 13.0 0.1 0.11 11.9 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.4 CAM66523.1 - 0.059 12.3 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PduV-EutP PF10662.4 CAM66523.1 - 0.064 12.7 0.1 0.36 10.3 0.0 2.2 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 CAM66523.1 - 0.088 13.0 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_35 PF14516.1 CAM66523.1 - 0.096 11.2 0.0 0.2 10.2 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain PIF1 PF05970.9 CAM66523.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase DAP3 PF10236.4 CAM66523.1 - 0.14 11.0 0.1 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Complex1_LYR PF05347.10 CAM66525.1 - 5.8e-08 32.4 0.1 1.3e-07 31.2 0.1 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CAM66525.1 - 6.9e-07 29.3 0.3 1.4e-06 28.3 0.2 1.7 1 1 0 1 1 1 1 Complex1_LYR-like DUF3945 PF13101.1 CAM66525.1 - 0.088 12.1 0.0 0.38 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3945) DUF3357 PF11837.3 CAM66526.1 - 0.043 13.6 0.1 0.64 9.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) Tmemb_185A PF10269.4 CAM66526.1 - 0.052 13.1 1.0 0.3 10.6 0.0 2.0 2 0 0 2 2 2 0 Transmembrane Fragile-X-F protein DUF4149 PF13664.1 CAM66526.1 - 0.059 13.4 0.1 0.79 9.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) DUF3733 PF12534.3 CAM66526.1 - 0.1 11.8 0.5 0.21 10.8 0.3 1.5 1 0 0 1 1 1 0 Leucine-rich repeat containing protein 8 DUF3753 PF12575.3 CAM66526.1 - 0.79 9.5 5.7 0.15 11.8 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) Shisa PF13908.1 CAM66527.1 - 0.00029 21.0 0.2 0.00052 20.2 0.1 1.5 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator SCIMP PF15050.1 CAM66527.1 - 0.007 16.2 0.2 0.017 15.0 0.1 1.7 1 0 0 1 1 1 1 SCIMP protein DUF4492 PF14899.1 CAM66527.1 - 0.015 14.8 0.8 0.027 13.9 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) GP41 PF00517.12 CAM66527.1 - 0.032 13.7 1.5 0.049 13.1 1.0 1.2 1 0 0 1 1 1 0 Retroviral envelope protein Rhabdo_glycop PF00974.13 CAM66527.1 - 0.11 10.7 1.9 0.16 10.1 1.3 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Orthoreo_P10 PF07204.6 CAM66527.1 - 0.87 9.3 3.2 0.78 9.5 1.2 1.6 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 Tetraspannin PF00335.15 CAM66527.1 - 1 8.6 5.5 1.7 7.8 3.8 1.3 1 0 0 1 1 1 0 Tetraspanin family DUF3753 PF12575.3 CAM66527.1 - 2.3 8.0 5.8 4.5 7.1 4.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) NPV_P10 PF05531.7 CAM66529.1 - 8.6 6.6 6.7 14 6.0 2.4 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Dpy-30 PF05186.8 CAM66530.1 - 4.3e-14 51.7 0.5 9.6e-14 50.5 0.4 1.6 1 0 0 1 1 1 1 Dpy-30 motif AAA_17 PF13207.1 CAM66530.1 - 1.2e-08 35.8 0.0 8.4e-08 33.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CAM66530.1 - 0.02 14.7 0.0 0.32 10.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 CAM66530.1 - 0.19 11.9 0.0 0.4 10.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNB PF00773.14 CAM66530.1 - 0.25 10.6 0.0 0.47 9.6 0.0 1.3 1 0 0 1 1 1 0 RNB domain Sin_N PF04801.8 CAM66532.1 - 1.5e-62 211.8 0.0 2.8e-62 210.9 0.0 1.4 2 0 0 2 2 2 1 Sin-like protein conserved region Botulinum_HA-17 PF05588.6 CAM66532.1 - 0.14 12.0 0.1 11 5.9 0.0 2.3 2 0 0 2 2 2 0 Clostridium botulinum HA-17 protein EMP70 PF02990.11 CAM66533.1 - 1.2e-89 301.1 24.5 1.2e-89 301.1 17.0 2.3 2 1 0 2 2 2 1 Endomembrane protein 70 Lactamase_B_2 PF12706.2 CAM66534.1 - 3.1e-27 95.3 0.2 5.4e-27 94.6 0.2 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CAM66534.1 - 1e-12 48.0 0.1 1e-11 44.8 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CAM66534.1 - 0.075 12.6 0.0 0.4 10.2 0.0 2.0 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily WD40 PF00400.27 CAM66535.1 - 0.00035 20.3 1.2 0.36 10.7 0.0 4.1 3 0 0 3 3 3 2 WD domain, G-beta repeat UQ_con PF00179.21 CAM66537.1 - 1.1e-14 54.0 0.0 1.2e-14 53.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CAM66537.1 - 0.0017 18.2 0.0 0.0018 18.1 0.0 1.2 1 0 0 1 1 1 1 RWD domain LRR_4 PF12799.2 CAM66538.1 - 7.3e-10 38.2 7.0 1.9e-06 27.3 0.5 2.8 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM66538.1 - 1.4e-05 24.7 15.7 0.00062 19.4 1.1 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_6 PF13516.1 CAM66538.1 - 0.001 18.9 5.6 0.16 12.0 0.2 4.0 2 1 1 3 3 3 1 Leucine Rich repeat LRR_7 PF13504.1 CAM66538.1 - 0.0036 17.2 5.7 0.97 9.9 0.0 3.9 3 0 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 CAM66538.1 - 0.0063 16.3 7.9 6.7 7.1 0.0 4.4 5 0 0 5 5 5 2 Leucine Rich Repeat EF-hand_1 PF00036.27 CAM66541.1 - 1.2e-24 83.6 0.0 1.3e-05 24.1 0.0 5.1 5 0 0 5 5 5 5 EF hand EF-hand_6 PF13405.1 CAM66541.1 - 6.3e-22 75.4 0.7 0.00023 20.7 0.0 5.1 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.1 CAM66541.1 - 7.9e-21 73.9 0.4 9.3e-10 38.5 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.1 CAM66541.1 - 4.9e-17 61.2 0.4 2.4e-06 27.0 0.0 4.5 3 2 2 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.1 CAM66541.1 - 3.7e-14 51.3 0.4 9.1e-06 24.7 0.0 4.0 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 CAM66541.1 - 0.0073 16.1 0.1 7.5 6.5 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain Phage_T4_Ndd PF06591.6 CAM66541.1 - 0.025 14.1 0.2 0.034 13.7 0.1 1.2 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) Spindle_Spc25 PF08234.7 CAM66541.1 - 0.19 11.7 0.7 4.1 7.4 0.1 2.5 2 0 0 2 2 2 0 Chromosome segregation protein Spc25 HECT PF00632.20 CAM66542.1 - 1e-10 41.2 0.0 1.2e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.23 CAM66543.2 - 6.5e-23 81.1 1.6 3.8e-09 36.6 0.0 3.7 3 0 0 3 3 3 3 SPRY domain DUF1825 PF08855.5 CAM66543.2 - 5.2 7.1 0.0 12 5.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1825) Ran_BP1 PF00638.13 CAM66544.1 - 5e-26 91.1 1.2 6.7e-26 90.7 0.9 1.1 1 0 0 1 1 1 1 RanBP1 domain Polyketide_cyc2 PF10604.4 CAM66544.1 - 0.014 15.5 0.2 0.017 15.2 0.1 1.2 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport WH1 PF00568.18 CAM66544.1 - 0.032 13.9 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 WH1 domain Lactamase_B_2 PF12706.2 CAM66545.1 - 7.1e-06 25.7 0.2 7.4e-05 22.3 0.2 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain DRMBL PF07522.9 CAM66545.1 - 0.0026 17.7 0.0 0.008 16.2 0.0 1.8 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.22 CAM66545.1 - 0.0026 17.4 0.1 0.014 15.0 0.3 2.0 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily PIN_4 PF13638.1 CAM66546.1 - 9.9e-19 67.7 0.0 1.9e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 PIN domain Metallophos PF00149.23 CAM66548.1 - 3.9e-28 98.2 0.0 5.8e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase AAA PF00004.24 CAM66549.2 - 4.4e-18 65.7 0.0 1.2e-17 64.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CAM66549.2 - 0.0019 17.2 0.0 0.004 16.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 CAM66549.2 - 0.0025 17.2 0.0 0.096 12.0 0.1 2.5 1 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CAM66549.2 - 0.011 15.5 4.5 0.1 12.3 0.0 3.8 3 1 1 4 4 4 0 Part of AAA domain AAA_22 PF13401.1 CAM66549.2 - 0.015 15.4 0.0 0.071 13.2 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CAM66549.2 - 0.02 15.6 0.0 0.082 13.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CAM66549.2 - 0.044 13.7 0.0 0.044 13.7 0.0 3.4 3 1 1 4 4 4 0 AAA ATPase domain RNA_helicase PF00910.17 CAM66549.2 - 0.057 13.6 0.0 0.54 10.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 CAM66549.2 - 0.16 11.8 0.0 0.99 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain E1-E2_ATPase PF00122.15 CAM66550.1 - 4.1e-21 75.0 0.0 2.5e-20 72.5 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CAM66550.1 - 3.9e-13 50.3 0.0 3.4e-12 47.2 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CAM66550.1 - 2.7e-12 47.2 0.1 6.8e-12 45.9 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CAM66550.1 - 3.7e-10 39.6 0.0 1.5e-09 37.6 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CAM66550.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase NIF PF03031.13 CAM66551.1 - 0.08 12.6 0.0 3.7 7.1 0.0 2.3 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase DUF2514 PF10721.4 CAM66551.1 - 0.2 11.3 4.5 0.72 9.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) Gtr1_RagA PF04670.7 CAM66553.1 - 1.7e-90 302.2 0.0 2.3e-90 301.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 CAM66553.1 - 4.4e-05 22.9 0.0 0.00012 21.5 0.0 1.7 2 0 0 2 2 2 1 Ras family Arf PF00025.16 CAM66553.1 - 0.00016 20.9 0.0 0.001 18.3 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 CAM66553.1 - 0.007 16.8 0.0 0.019 15.4 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Metallophos PF00149.23 CAM66554.1 - 3.1e-27 95.2 0.0 5.2e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Tcp10_C PF07202.8 CAM66555.1 - 1.7e-28 99.3 0.0 3.4e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 T-complex protein 10 C-terminus HALZ PF02183.13 CAM66555.1 - 0.0069 16.0 4.1 0.015 15.0 0.4 2.5 2 0 0 2 2 2 1 Homeobox associated leucine zipper OPT PF03169.10 CAM66556.2 - 0.27 9.6 0.6 0.42 8.9 0.4 1.2 1 0 0 1 1 1 0 OPT oligopeptide transporter protein MtrB PF05440.7 CAM66556.2 - 0.46 10.5 0.0 0.46 10.5 0.0 4.3 6 0 0 6 6 6 0 Tetrahydromethanopterin S-methyltransferase subunit B UCH PF00443.24 CAM66556.2 - 6.6 5.7 8.1 16 4.4 1.3 3.3 1 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Kinesin PF00225.18 CAM66557.1 - 6.7e-93 311.0 0.0 9e-93 310.6 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain SAM_1 PF00536.25 CAM66557.1 - 8.6e-05 22.6 3.3 0.00017 21.6 0.2 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 CAM66557.1 - 0.064 13.1 0.2 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SE PF08491.5 CAM66558.1 - 2.3e-55 187.3 0.0 3.2e-55 186.8 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 CAM66558.1 - 4.2e-08 32.6 0.0 1.4e-07 30.9 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 CAM66558.1 - 0.0069 15.3 0.1 1.1 8.0 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein GDI PF00996.13 CAM66558.1 - 0.0075 14.6 0.0 0.011 14.0 0.0 1.2 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 CAM66558.1 - 0.03 14.3 0.0 0.11 12.5 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CAM66558.1 - 0.043 13.6 0.3 0.24 11.2 0.0 1.9 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CAM66558.1 - 0.049 14.0 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CAM66558.1 - 0.056 12.3 0.0 0.15 10.9 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 CAM66558.1 - 0.17 10.9 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DNA_pol_A PF00476.15 CAM66559.2 - 3.4e-32 111.5 0.0 7.2e-32 110.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 CAM66559.2 - 0.0037 16.7 0.0 0.017 14.6 0.0 2.1 3 0 0 3 3 3 1 3'-5' exonuclease Pkinase PF00069.20 CAM66560.2 - 1.3e-51 175.2 0.0 7.2e-31 107.2 0.0 3.4 2 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAM66560.2 - 6.1e-20 71.3 0.0 3.1e-16 59.2 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 CAM66560.2 - 0.0029 17.3 0.7 0.016 14.9 0.1 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CAM66560.2 - 0.013 14.4 0.0 0.042 12.8 0.0 1.8 2 0 0 2 2 2 0 Kinase-like YlbD_coat PF14071.1 CAM66561.1 - 0.053 13.5 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative coat protein PI3Ka PF00613.15 CAM66562.1 - 3.3e-47 160.0 1.7 6.3e-47 159.1 1.2 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 CAM66562.1 - 3.6e-46 157.5 0.0 6.2e-46 156.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_rbd PF00794.13 CAM66562.1 - 9.7e-12 44.7 0.0 2.1e-09 37.2 0.0 3.6 4 0 0 4 4 4 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.19 CAM66562.1 - 1.7e-08 34.3 0.0 4.1e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 SNF2_N PF00176.18 CAM66564.1 - 4.4e-24 84.8 0.0 7.5e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Tet_JBP PF12851.2 CAM66564.1 - 1e-23 83.5 0.4 1.9e-23 82.5 0.1 1.7 2 0 0 2 2 2 1 Oxygenase domain of the 2OGFeDO superfamily Helicase_C PF00271.26 CAM66564.1 - 5.1e-13 48.6 0.1 1e-12 47.6 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAM66564.1 - 1.2e-05 25.2 0.0 5.8e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CAM66564.1 - 0.008 15.6 0.0 0.022 14.2 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF2095 PF09868.4 CAM66564.1 - 0.036 13.8 0.1 0.088 12.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) cNMP_binding PF00027.24 CAM66565.1 - 2.2e-05 24.1 0.0 0.91 9.3 0.0 3.7 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Arf PF00025.16 CAM66566.1 - 2.5e-05 23.5 0.0 6.3e-05 22.2 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_28 PF13521.1 CAM66566.1 - 0.0065 16.4 0.2 0.01 15.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain zf-DHHC PF01529.15 CAM66567.1 - 2e-27 95.7 7.2 2e-27 95.7 5.0 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase Yip1 PF04893.12 CAM66567.1 - 1.2 8.5 16.3 0.36 10.3 2.8 2.8 2 1 1 3 3 3 0 Yip1 domain PRP1_N PF06424.7 CAM66568.1 - 0.035 14.4 0.2 0.035 14.4 0.1 1.8 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal DnaJ PF00226.26 CAM66569.1 - 1.5e-05 24.6 0.0 3.9e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain CH PF00307.26 CAM66570.1 - 0.018 15.1 0.0 0.072 13.1 0.0 2.1 1 0 0 1 1 1 0 Calponin homology (CH) domain KLRAQ PF10205.4 CAM66570.1 - 0.043 13.8 10.9 0.97 9.5 7.6 2.9 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein DnaJ PF00226.26 CAM66571.1 - 1.1e-14 53.9 0.6 1.9e-14 53.1 0.4 1.5 1 0 0 1 1 1 1 DnaJ domain IU_nuc_hydro PF01156.14 CAM66573.1 - 3.4e-70 236.7 0.1 4.1e-70 236.4 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase MOZ_SAS PF01853.13 CAM66574.1 - 2.7e-63 212.6 0.0 4.1e-63 212.0 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 CAM66574.1 - 7.6e-09 35.1 0.1 1.9e-08 33.8 0.1 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.19 CAM66574.1 - 0.0012 18.7 0.0 0.12 12.4 0.0 2.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.1 CAM66574.1 - 0.058 13.2 0.0 7.6 6.4 0.1 2.6 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase DUF4286 PF14114.1 CAM66574.1 - 0.058 13.6 0.4 0.19 12.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) zf-Di19 PF05605.7 CAM66574.1 - 0.96 9.6 5.7 4.5 7.4 0.6 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Ribosomal_L12 PF00542.14 CAM66575.1 - 5.2e-16 58.4 4.3 5.2e-16 58.4 3.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain SseC PF04888.7 CAM66575.1 - 0.1 11.9 4.5 0.12 11.6 3.1 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DUF3138 PF11336.3 CAM66575.1 - 0.11 10.6 0.1 0.13 10.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) PepSY_2 PF13670.1 CAM66575.1 - 1.1 9.2 10.9 11 5.9 3.9 3.0 2 1 1 3 3 3 0 Peptidase propeptide and YPEB domain Ribosomal_60s PF00428.14 CAM66575.1 - 2.3 8.6 14.8 0.52 10.7 7.2 2.2 1 1 1 2 2 2 0 60s Acidic ribosomal protein Chromo PF00385.19 CAM66576.2 - 0.00035 20.1 0.3 0.00064 19.3 0.2 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Peptidase_M32 PF02074.10 CAM66578.1 - 7.3e-100 334.9 0.0 8.2e-100 334.7 0.0 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase Thioredoxin_8 PF13905.1 CAM66579.1 - 1.6e-07 31.3 0.1 2.7e-07 30.6 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 CAM66579.1 - 9.5e-05 22.0 0.1 0.00013 21.6 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CAM66579.1 - 0.00025 20.5 0.1 0.0003 20.3 0.1 1.2 1 0 0 1 1 1 1 Redoxin BBIP10 PF14777.1 CAM66580.1 - 3.7e-14 51.8 2.4 5.8e-14 51.2 1.7 1.2 1 0 0 1 1 1 1 Cilia BBSome complex subunit 10 MCPVI PF02993.9 CAM66580.1 - 0.33 11.0 6.4 0.46 10.6 4.4 1.1 1 0 0 1 1 1 0 Minor capsid protein VI DUF4201 PF13870.1 CAM66581.1 - 1.4e-31 109.3 9.6 1.4e-31 109.3 6.7 2.8 3 1 0 3 3 3 1 Domain of unknown function (DUF4201) GAS PF13851.1 CAM66581.1 - 3.8 6.6 25.2 1.1 8.4 1.1 3.7 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.3 CAM66581.1 - 4.6 7.1 12.1 1.9 8.3 1.7 3.6 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DivIVA PF05103.8 CAM66581.1 - 5.6 7.0 25.7 0.045 13.7 3.5 3.5 3 1 0 3 3 3 0 DivIVA protein PX PF00787.19 CAM66582.1 - 6.2e-10 38.8 0.0 3.6e-09 36.4 0.0 2.2 2 0 0 2 2 2 1 PX domain Sec5 PF15469.1 CAM66583.1 - 1.6e-06 27.9 0.0 3.3e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component Sec5 PPP4R2 PF09184.6 CAM66583.1 - 3.1 7.2 5.9 5.9 6.3 4.1 1.4 1 0 0 1 1 1 0 PPP4R2 HIT PF01230.18 CAM66584.1 - 2.1e-23 82.6 0.1 2.8e-23 82.2 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 CAM66584.1 - 5.1e-16 58.9 0.0 6.6e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 CAM66584.1 - 0.013 15.1 4.1 0.014 15.0 1.6 2.0 2 1 0 2 2 2 0 Protein similar to CwfJ C-terminus 1 TRAP-gamma PF07074.7 CAM66585.1 - 2.7e-08 33.5 3.7 0.00055 19.4 0.1 2.1 2 0 0 2 2 2 2 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF2721 PF11026.3 CAM66585.1 - 0.096 12.3 1.2 0.15 11.7 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF4386 PF14329.1 CAM66585.1 - 0.12 11.8 1.7 0.33 10.3 1.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4386) VWA_3 PF13768.1 CAM66586.1 - 6.6e-09 35.6 0.5 6.6e-09 35.6 0.4 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT_2 PF13757.1 CAM66586.1 - 0.025 14.0 0.1 0.13 11.6 0.0 2.3 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain Na_Ca_ex PF01699.19 CAM66587.1 - 6.7e-07 28.9 24.7 0.00011 21.8 8.1 3.1 2 1 0 2 2 2 2 Sodium/calcium exchanger protein SpoIIIAC PF06686.6 CAM66587.1 - 0.85 9.4 3.8 0.65 9.8 0.3 2.5 2 0 0 2 2 2 0 Stage III sporulation protein AC/AD protein family zf-CCHC_4 PF14392.1 CAM66588.1 - 1 9.1 16.5 2.7 7.7 0.1 3.7 3 0 0 3 3 3 0 Zinc knuckle adh_short PF00106.20 CAM66589.1 - 0.013 15.4 0.4 0.028 14.3 0.3 1.5 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 CAM66589.1 - 0.061 12.1 1.1 0.38 9.5 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain 3Beta_HSD PF01073.14 CAM66589.1 - 0.11 11.2 0.3 0.22 10.1 0.0 1.8 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Proteasome PF00227.21 CAM66591.1 - 8.8e-51 171.8 0.0 1.2e-50 171.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CAM66591.1 - 8.4e-14 50.5 0.4 1.5e-13 49.7 0.3 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature AA_permease_2 PF13520.1 CAM66592.1 - 7.6e-33 113.6 41.8 1.1e-32 113.1 28.9 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CAM66592.1 - 2.1e-13 49.4 36.1 4.8e-13 48.2 25.0 1.5 1 1 0 1 1 1 1 Amino acid permease Aa_trans PF01490.13 CAM66593.1 - 1.1e-21 76.8 21.9 1.5e-21 76.4 15.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein IPK PF03770.11 CAM66594.1 - 1.2e-42 145.8 0.1 1.9e-42 145.1 0.1 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase Thr_synth_N PF14821.1 CAM66595.1 - 4.4e-14 52.2 0.1 1.6e-13 50.4 0.0 2.0 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.20 CAM66595.1 - 9.3e-12 44.7 0.0 2.1e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme zf-CW PF07496.10 CAM66596.1 - 7e-05 22.4 1.8 0.00016 21.3 1.3 1.6 1 0 0 1 1 1 1 CW-type Zinc Finger Bromodomain PF00439.20 CAM66596.1 - 0.016 15.0 0.0 0.12 12.2 0.0 2.1 1 1 0 1 1 1 0 Bromodomain zf-DNL PF05180.7 CAM66596.1 - 0.34 10.6 1.4 0.51 10.0 0.4 1.6 1 1 0 1 1 1 0 DNL zinc finger Choline_transpo PF04515.7 CAM66598.1 - 1.2e-74 251.0 41.3 1.2e-74 251.0 28.6 2.4 3 0 0 3 3 3 2 Plasma-membrane choline transporter ATP-synt_D PF01813.12 CAM66601.1 - 0.0058 16.2 0.7 0.18 11.3 0.1 2.2 2 1 0 2 2 2 2 ATP synthase subunit D DUF2984 PF11203.3 CAM66601.1 - 4.2 7.5 7.2 0.28 11.3 1.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2984) DUF1253 PF06862.7 CAM66602.1 - 9.7e-122 406.5 0.0 1.4e-121 406.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) Dzip-like_N PF13815.1 CAM66603.1 - 6.5e-37 125.9 3.1 6.5e-37 125.9 2.2 2.0 2 0 0 2 2 2 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-Di19 PF05605.7 CAM66603.1 - 0.00058 19.9 0.2 0.0011 19.0 0.1 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 CAM66603.1 - 0.046 14.0 1.5 0.1 12.9 1.1 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CAM66603.1 - 0.046 14.0 1.0 0.11 12.8 0.7 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 CAM66603.1 - 0.12 12.4 0.6 0.42 10.7 0.0 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) mRNA_triPase PF02940.10 CAM66604.1 - 2.3e-10 40.5 0.0 1.4e-08 34.7 0.0 2.6 2 1 0 2 2 2 1 mRNA capping enzyme, beta chain Pyr_redox_2 PF07992.9 CAM66605.1 - 2.7e-10 40.4 0.0 1.5e-06 28.2 0.0 2.8 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CAM66605.1 - 8.7e-10 38.8 0.0 3e-06 27.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CAM66605.1 - 1.1e-06 27.8 0.0 0.0035 16.3 0.0 3.2 3 0 0 3 3 3 2 Lycopene cyclase protein DAO PF01266.19 CAM66605.1 - 1.4e-05 24.1 0.0 0.023 13.5 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CAM66605.1 - 2.1e-05 24.7 0.0 0.00059 19.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CAM66605.1 - 2.2e-05 24.2 0.0 0.069 12.9 0.0 3.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 CAM66605.1 - 8.4e-05 22.5 0.0 0.56 10.2 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 CAM66605.1 - 0.00066 18.6 0.0 0.0024 16.8 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 CAM66605.1 - 0.006 16.8 0.0 1.5 9.1 0.0 2.7 3 0 0 3 3 3 1 Putative NAD(P)-binding 3HCDH_N PF02737.13 CAM66605.1 - 0.013 15.1 0.0 0.16 11.5 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 CAM66605.1 - 0.015 15.0 0.0 0.036 13.7 0.0 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.14 CAM66605.1 - 0.06 12.3 0.1 0.8 8.6 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 CAM66605.1 - 0.078 12.0 0.0 1.1 8.3 0.0 2.3 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.15 CAM66605.1 - 0.08 13.0 0.0 48 4.0 0.0 3.2 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 CAM66605.1 - 0.089 11.6 0.0 11 4.7 0.0 2.8 3 0 0 3 3 3 0 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.9 CAM66605.1 - 0.092 12.1 0.0 4.9 6.4 0.0 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 CAM66605.1 - 0.12 12.3 0.0 10 6.1 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain Nudc_N PF14050.1 CAM66606.1 - 4.8e-19 68.0 0.3 1.3e-18 66.7 0.2 1.7 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. CS PF04969.11 CAM66606.1 - 2.3e-16 60.0 0.0 4e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 CS domain KTI12 PF08433.5 CAM66606.1 - 0.26 10.4 7.0 0.41 9.7 0.1 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 DUF4407 PF14362.1 CAM66606.1 - 1.7 7.5 15.5 2.6 6.9 10.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spore_coat_CotO PF14153.1 CAM66606.1 - 2.3 7.6 16.6 0.066 12.6 6.4 1.9 2 0 0 2 2 2 0 Spore coat protein CotO Cys_Met_Meta_PP PF01053.15 CAM66607.2 - 7.3e-116 386.6 0.0 9.2e-116 386.2 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 CAM66607.2 - 0.00063 18.5 0.1 0.0011 17.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CAM66607.2 - 0.073 12.1 0.1 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Amastin PF07344.6 CAM66609.1 - 1.4e-05 24.8 14.6 1.4e-05 24.8 10.1 2.4 1 1 0 2 2 2 1 Amastin surface glycoprotein Lig_chan PF00060.21 CAM66609.1 - 2.2 8.0 6.8 0.75 9.5 2.2 2.0 1 1 1 2 2 2 0 Ligand-gated ion channel Amastin PF07344.6 CAM66610.1 - 4.6e-06 26.3 22.8 3.8e-05 23.3 14.0 2.4 1 1 1 2 2 2 1 Amastin surface glycoprotein NnrU PF07298.6 CAM66610.1 - 0.12 11.7 6.6 0.33 10.2 1.8 2.3 2 0 0 2 2 2 0 NnrU protein Lig_chan PF00060.21 CAM66610.1 - 4.5 6.9 8.5 0.82 9.3 2.5 2.1 1 1 1 2 2 2 0 Ligand-gated ion channel DUF842 PF05811.8 CAM66611.1 - 2.7 7.4 8.0 5.7 6.3 0.6 3.1 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF842) IncA PF04156.9 CAM66611.1 - 8.2 5.9 16.4 1.6 8.3 0.3 3.6 3 1 0 3 3 3 0 IncA protein FA_desaturase PF00487.19 CAM66612.1 - 3.9e-18 65.8 17.8 3.9e-18 65.8 12.3 1.8 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 CAM66612.1 - 6.8e-10 38.6 0.1 8.1e-07 28.7 0.0 2.6 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Voltage_CLC PF00654.15 CAM66612.1 - 1.3 7.9 10.1 3.8 6.4 7.0 1.7 1 1 0 1 1 1 0 Voltage gated chloride channel IclR PF01614.13 CAM66613.1 - 0.024 14.3 1.9 0.031 13.9 1.3 1.1 1 0 0 1 1 1 0 Bacterial transcriptional regulator LPP20 PF02169.11 CAM66613.1 - 0.042 13.9 1.4 0.062 13.3 0.9 1.4 1 0 0 1 1 1 0 LPP20 lipoprotein DUF2336 PF10098.4 CAM66613.1 - 0.045 12.9 7.0 0.047 12.9 4.9 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2336) FemAB PF02388.11 CAM66613.1 - 0.088 11.4 1.3 0.095 11.3 0.9 1.1 1 0 0 1 1 1 0 FemAB family FANCF PF11107.3 CAM66613.1 - 0.11 11.6 1.0 0.13 11.5 0.7 1.0 1 0 0 1 1 1 0 Fanconi anemia group F protein (FANCF) Atg14 PF10186.4 CAM66613.1 - 0.32 9.9 2.1 0.37 9.6 1.5 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Wbp11 PF09429.5 CAM66613.1 - 4.2 7.4 7.9 9.3 6.3 5.5 1.6 1 1 0 1 1 1 0 WW domain binding protein 11 Ion_trans_2 PF07885.11 CAM66614.1 - 8e-10 38.2 5.9 2.7e-09 36.5 4.1 1.9 1 0 0 1 1 1 1 Ion channel Ion_trans_2 PF07885.11 CAM66615.1 - 1.8e-11 43.5 8.3 1.8e-11 43.5 5.8 2.4 2 0 0 2 2 2 1 Ion channel Lig_chan PF00060.21 CAM66615.1 - 3.8e-05 23.4 1.8 8.5e-05 22.3 1.2 1.9 1 1 0 1 1 1 1 Ligand-gated ion channel Ion_trans PF00520.26 CAM66615.1 - 0.0062 15.8 18.5 0.051 12.8 12.8 2.5 1 1 0 1 1 1 1 Ion transport protein FliT PF05400.8 CAM66615.1 - 0.044 14.2 1.8 0.059 13.7 0.1 2.0 2 0 0 2 2 2 0 Flagellar protein FliT IncA PF04156.9 CAM66617.1 - 0.0012 18.4 1.2 0.002 17.7 0.8 1.3 1 0 0 1 1 1 1 IncA protein T2SM PF04612.7 CAM66617.1 - 0.0072 16.1 0.3 0.0072 16.1 0.2 1.9 1 1 1 2 2 2 1 Type II secretion system (T2SS), protein M WD40 PF00400.27 CAM66618.1 - 5.2e-29 99.0 19.8 6.5e-06 25.8 0.1 10.5 11 0 0 11 11 11 6 WD domain, G-beta repeat Utp12 PF04003.7 CAM66618.1 - 6e-05 22.9 0.1 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 CAM66618.1 - 0.0012 17.0 1.4 0.27 9.3 0.1 2.9 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CAM66618.1 - 0.041 12.6 0.1 14 4.3 0.0 3.3 3 1 1 4 4 4 0 Nup133 N terminal like Complex1_LYR PF05347.10 CAM66619.1 - 0.0053 16.5 0.4 0.0091 15.7 0.3 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) YLP PF02757.12 CAM66619.1 - 0.15 11.8 0.2 0.33 10.7 0.1 1.6 1 0 0 1 1 1 0 YLP motif SpoU_methylase PF00588.14 CAM66621.1 - 3.9e-10 39.7 0.0 0.00032 20.6 0.0 2.2 2 0 0 2 2 2 2 SpoU rRNA Methylase family Spt5_N PF11942.3 CAM66622.1 - 0.22 12.1 7.2 0.72 10.5 5.0 1.9 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Nop14 PF04147.7 CAM66622.1 - 0.31 8.8 2.6 0.5 8.2 1.8 1.3 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.8 CAM66622.1 - 0.46 10.3 8.5 1.2 8.9 5.8 1.7 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.9 CAM66622.1 - 0.87 7.5 3.0 1.4 6.8 2.1 1.3 1 0 0 1 1 1 0 CDC45-like protein zf-LSD1 PF06943.7 CAM66624.1 - 2.2e-07 30.3 9.3 2.2e-07 30.3 6.4 3.1 2 1 1 3 3 3 1 LSD1 zinc finger zinc_ribbon_4 PF13717.1 CAM66624.1 - 0.017 14.8 0.5 0.017 14.8 0.3 3.2 3 1 1 4 4 4 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CAM66624.1 - 0.017 14.6 0.5 0.017 14.6 0.4 3.2 3 1 1 4 4 4 0 zinc-ribbon domain zf-NADH-PPase PF09297.6 CAM66624.1 - 0.11 12.0 3.4 0.32 10.5 2.4 1.8 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain C1_1 PF00130.17 CAM66624.1 - 1.9 8.2 9.3 2.6 7.8 0.8 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.2 CAM66624.1 - 2.8 7.8 11.4 0.57 10.0 4.0 2.2 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_6 PF14599.1 CAM66624.1 - 7.9 6.3 8.0 1.6 8.5 0.6 2.2 1 1 1 2 2 2 0 Zinc-ribbon PHD PF00628.24 CAM66624.1 - 8.1 6.2 9.9 0.09 12.4 0.7 2.3 3 0 0 3 3 3 0 PHD-finger ELO PF01151.13 CAM66625.1 - 7.3e-36 123.7 9.6 8.9e-36 123.4 6.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family MCR_alpha PF02249.12 CAM66625.1 - 0.038 14.0 2.6 0.063 13.2 0.4 2.2 3 0 0 3 3 3 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain ELO PF01151.13 CAM66626.1 - 1.1e-64 218.2 15.4 1.2e-64 218.0 10.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF1240 PF06836.7 CAM66626.1 - 0.039 14.1 1.4 0.039 14.1 1.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1240) ELO PF01151.13 CAM66627.1 - 2.9e-61 206.9 13.7 3.3e-61 206.7 9.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.13 CAM66628.1 - 1.3e-61 208.1 13.8 1.4e-61 207.9 9.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.13 CAM66630.1 - 5.5e-68 228.9 5.5 6.4e-68 228.7 3.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.13 CAM66632.1 - 9.7e-76 254.3 19.0 1.2e-75 254.1 13.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Sdh_cyt PF01127.17 CAM66632.1 - 1.1 9.1 7.0 2.7 7.8 4.8 1.7 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit ELO PF01151.13 CAM66633.1 - 7.4e-75 251.4 8.8 9.3e-75 251.1 6.1 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF4199 PF13858.1 CAM66633.1 - 2.3 8.1 9.0 0.088 12.7 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) ELO PF01151.13 CAM66634.1 - 1.8e-83 279.6 16.7 2.4e-83 279.3 11.6 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.13 CAM66635.1 - 2.7e-70 236.5 19.9 3.1e-70 236.3 13.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.13 CAM66636.1 - 2.3e-70 236.7 23.0 2.7e-70 236.5 16.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family PAC2 PF09754.4 CAM66636.1 - 0.07 12.9 0.2 0.97 9.2 0.1 2.2 1 1 0 1 1 1 0 PAC2 family ELO PF01151.13 CAM66637.1 - 3.4e-72 242.7 20.3 4e-72 242.5 14.1 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.13 CAM66638.1 - 6e-74 248.4 22.7 7.2e-74 248.2 15.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF106 PF01956.11 CAM66638.1 - 0.17 11.3 2.4 0.7 9.4 1.8 2.0 2 0 0 2 2 2 0 Integral membrane protein DUF106 Ras PF00071.17 CAM66640.2 - 6e-36 123.2 0.0 8.2e-36 122.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAM66640.2 - 9.4e-16 58.3 0.0 1.6e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAM66640.2 - 2.8e-09 36.4 0.0 4.1e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CAM66640.2 - 3.8e-05 22.9 0.0 5.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CAM66640.2 - 0.0095 15.8 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CAM66640.2 - 0.022 14.9 0.0 0.045 13.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CAM66640.2 - 0.032 14.1 0.5 0.84 9.5 0.4 2.2 1 1 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 CAM66640.2 - 0.14 11.2 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Ribosomal_L21p PF00829.16 CAM66642.1 - 2.5e-18 65.9 0.0 3.5e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein PsbP PF01789.11 CAM66642.1 - 0.15 11.4 0.1 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 PsbP Hid1 PF12722.2 CAM66644.1 - 3.8 5.0 5.4 4.6 4.7 3.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Kinesin PF00225.18 CAM66645.1 - 2.5e-90 302.5 0.0 4.7e-90 301.6 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain DUF4201 PF13870.1 CAM66646.1 - 3.9e-32 111.1 18.3 3.9e-32 111.1 12.7 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4201) KxDL PF10241.4 CAM66646.1 - 0.005 16.7 2.0 0.005 16.7 1.4 2.8 3 0 0 3 3 3 1 Uncharacterized conserved protein DUF948 PF06103.6 CAM66646.1 - 0.013 15.3 4.4 2.1 8.2 0.2 3.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) SlyX PF04102.7 CAM66646.1 - 0.58 10.5 0.0 0.58 10.5 0.0 5.2 3 2 1 4 4 4 0 SlyX Pkinase PF00069.20 CAM66647.1 - 1.7e-44 151.9 0.0 2.8e-24 85.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAM66647.1 - 1.5e-13 50.4 0.0 3.4e-09 36.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CAM66647.1 - 4.2e-05 23.3 0.0 7.8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CAM66647.1 - 0.026 14.0 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 CAM66647.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family SNF2_N PF00176.18 CAM66648.1 - 2.9e-61 206.8 0.0 4.9e-61 206.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CAM66648.1 - 1.1e-13 50.8 0.3 1e-12 47.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAM66648.1 - 1.8e-06 27.5 0.0 5.2e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CAM66648.1 - 0.0008 19.2 0.0 0.0061 16.4 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 CAM66648.1 - 0.13 11.0 0.0 0.51 9.1 0.0 1.8 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 V_ATPase_I PF01496.14 CAM66648.1 - 0.16 9.7 2.8 0.28 9.0 1.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1935 PF09149.5 CAM66649.1 - 2.7e-38 130.1 0.1 3e-38 129.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.5 CAM66650.1 - 2.7e-38 130.1 0.1 3e-38 129.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) PP2C PF00481.16 CAM66654.1 - 6.9e-49 166.5 0.0 4.1e-48 164.0 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CAM66654.1 - 9.1e-08 31.7 0.1 4.8e-07 29.3 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C GSH_synth_ATP PF03917.12 CAM66655.1 - 1e-54 185.5 0.0 1.3e-52 178.6 0.0 3.0 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 CAM66655.1 - 4.1e-36 123.2 0.1 1e-35 121.9 0.1 1.7 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Tn7_Tnp_TnsA_C PF08721.6 CAM66655.1 - 0.051 13.5 0.0 1.3 9.1 0.0 2.9 3 0 0 3 3 3 0 TnsA endonuclease C terminal DUF972 PF06156.8 CAM66657.1 - 0.33 11.3 1.9 2.1 8.7 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF972) AAA_13 PF13166.1 CAM66657.1 - 0.93 7.8 7.0 1.4 7.2 3.6 1.9 1 1 1 2 2 2 0 AAA domain Med9 PF07544.8 CAM66657.1 - 5.6 6.7 7.4 13 5.6 0.1 3.6 3 1 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Mnd1 PF03962.10 CAM66657.1 - 8.6 5.9 8.9 0.4 10.3 1.5 2.1 2 0 0 2 2 2 0 Mnd1 family Ribosomal_L16 PF00252.13 CAM66659.1 - 7.2e-23 80.8 0.0 9.1e-23 80.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e PAP_assoc PF03828.14 CAM66660.1 - 6.9e-16 57.9 0.0 2.8e-11 43.1 0.0 2.8 3 0 0 3 3 3 2 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 CAM66660.1 - 0.049 13.9 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain AAA_18 PF13238.1 CAM66661.1 - 1e-07 32.3 0.0 0.0067 16.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain PRK PF00485.13 CAM66661.1 - 4.5e-07 29.6 0.1 0.00045 19.8 0.0 2.4 3 0 0 3 3 2 2 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 CAM66661.1 - 0.00016 22.4 0.1 0.00037 21.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CAM66661.1 - 0.00021 20.9 0.0 0.00087 18.9 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 CAM66661.1 - 0.0033 16.8 0.0 0.0051 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CAM66661.1 - 0.0063 16.1 0.0 0.0097 15.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CAM66661.1 - 0.014 15.7 0.0 0.023 14.9 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 CAM66661.1 - 0.026 14.5 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 CAM66661.1 - 0.031 13.7 0.0 0.067 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 CAM66661.1 - 0.034 13.2 0.1 0.081 12.0 0.1 1.7 1 1 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.18 CAM66661.1 - 0.035 14.0 0.0 0.091 12.7 0.0 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.1 CAM66661.1 - 0.047 13.5 0.0 0.6 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 CAM66661.1 - 0.05 12.8 0.0 0.099 11.8 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ArgK PF03308.11 CAM66661.1 - 0.05 12.3 0.0 0.081 11.6 0.0 1.2 1 0 0 1 1 1 0 ArgK protein FtsK_SpoIIIE PF01580.13 CAM66661.1 - 0.055 12.9 0.0 0.09 12.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.7 CAM66661.1 - 0.086 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 CAM66661.1 - 0.089 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.10 CAM66661.1 - 0.096 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 NTPase Na_H_Exchanger PF00999.16 CAM66662.1 - 5.2e-18 64.7 26.9 1.1e-17 63.6 18.6 1.6 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Mito_carr PF00153.22 CAM66663.1 - 4.6e-27 93.5 0.0 9.3e-13 47.7 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.22 CAM66664.1 - 1.4e-07 31.1 0.0 0.0018 17.9 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein P16-Arc PF04699.9 CAM66665.1 - 0.23 11.4 0.1 17 5.3 0.0 3.2 4 0 0 4 4 4 0 ARP2/3 complex 16 kDa subunit (p16-Arc) DUF202 PF02656.10 CAM66668.1 - 2.3e-15 56.5 1.0 2.7e-14 53.1 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4293 PF14126.1 CAM66668.1 - 0.26 11.2 3.1 98 2.8 0.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) COQ9 PF08511.6 CAM66669.1 - 3.9e-06 26.2 0.0 1.7e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 COQ9 DUF4478 PF14793.1 CAM66669.1 - 0.072 12.6 0.1 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4478) Dynein_heavy PF03028.10 CAM66670.1 - 4.4e-139 464.6 0.0 1.5e-136 456.2 0.0 3.8 2 1 0 2 2 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 CAM66670.1 - 4.3e-120 400.9 5.1 4.8e-120 400.7 0.0 2.9 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CAM66670.1 - 4.9e-95 317.4 0.0 9.2e-95 316.5 0.0 1.5 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 CAM66670.1 - 4.2e-62 209.5 0.0 1.1e-61 208.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.2 CAM66670.1 - 8.3e-45 153.0 6.6 1.8e-44 151.8 4.5 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 CAM66670.1 - 2.2e-42 144.4 0.5 4.2e-42 143.5 0.4 1.4 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 CAM66670.1 - 8.4e-38 129.9 0.1 2.8e-37 128.2 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 CAM66670.1 - 2.5e-21 75.8 2.4 1.6e-06 27.9 0.0 5.9 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CAM66670.1 - 4.3e-06 26.8 10.5 0.014 15.5 0.0 7.0 6 1 1 7 7 6 1 AAA domain T2SE PF00437.15 CAM66670.1 - 4.3e-05 22.5 1.6 0.0023 16.8 0.1 3.1 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA PF00004.24 CAM66670.1 - 0.0004 20.5 0.9 2 8.6 0.0 4.4 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 CAM66670.1 - 0.0019 17.6 2.4 1.8 8.1 0.1 3.6 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_17 PF13207.1 CAM66670.1 - 0.021 15.6 0.4 32 5.3 0.0 4.1 4 0 0 4 4 4 0 AAA domain AAA_16 PF13191.1 CAM66670.1 - 0.1 12.6 32.9 0.4 10.6 0.0 7.7 8 1 1 9 9 9 0 AAA ATPase domain Mg_chelatase PF01078.16 CAM66670.1 - 0.1 11.7 5.0 3.4 6.7 0.0 4.3 6 0 0 6 6 6 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 CAM66670.1 - 0.18 12.0 0.2 15 5.7 0.0 4.0 4 0 0 4 4 4 0 RNA helicase Pkinase PF00069.20 CAM66671.1 - 6.3e-45 153.3 0.0 1.3e-44 152.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM66671.1 - 2.2e-17 63.0 0.0 3.6e-16 59.0 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase PQ-loop PF04193.9 CAM66673.1 - 3.6e-28 96.8 4.7 1.6e-13 49.9 0.1 2.3 2 0 0 2 2 2 2 PQ loop repeat Cast PF10174.4 CAM66678.1 - 3.9e-18 64.9 246.3 8.7e-08 30.7 67.2 4.9 1 1 4 5 5 5 5 RIM-binding protein of the cytomatrix active zone CENP-F_leu_zip PF10473.4 CAM66678.1 - 2.3e-10 40.4 284.9 0.53 10.1 19.7 12.3 1 1 12 13 13 13 10 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TUDOR PF00567.19 CAM66678.1 - 4.2e-08 33.0 21.7 7.1 6.4 0.0 11.9 2 2 11 17 17 17 1 Tudor domain Myosin_tail_1 PF01576.14 CAM66678.1 - 0.00055 17.8 276.6 0.002 15.9 59.3 4.4 1 1 3 4 4 4 4 Myosin tail L27_2 PF09045.5 CAM66678.1 - 0.0025 17.3 141.5 12 5.5 0.3 23.9 11 5 9 23 23 23 1 L27_2 MscS_porin PF12795.2 CAM66678.1 - 0.003 16.9 245.0 0.33 10.2 29.3 6.5 1 1 6 8 8 8 7 Mechanosensitive ion channel porin domain IncA PF04156.9 CAM66678.1 - 0.003 17.1 266.9 0.38 10.3 20.7 8.9 1 1 10 11 11 11 5 IncA protein COG5 PF10392.4 CAM66678.1 - 0.0054 16.6 87.1 4.3 7.2 1.1 15.5 1 1 17 19 19 19 2 Golgi transport complex subunit 5 Atg14 PF10186.4 CAM66678.1 - 0.49 9.2 196.6 0.017 14.0 14.9 8.7 1 1 8 9 9 8 0 UV radiation resistance protein and autophagy-related subunit 14 TPR_MLP1_2 PF07926.7 CAM66678.1 - 0.89 9.3 268.4 0.79 9.4 20.4 9.9 1 1 8 9 9 9 0 TPR/MLP1/MLP2-like protein Rootletin PF15035.1 CAM66678.1 - 2.2 8.2 239.9 5.4 6.9 1.7 21.3 1 1 20 21 21 21 0 Ciliary rootlet component, centrosome cohesion DUF4201 PF13870.1 CAM66678.1 - 7.4 5.9 181.4 0.68 9.3 11.8 10.1 1 1 10 11 11 11 0 Domain of unknown function (DUF4201) Kinesin PF00225.18 CAM66680.2 - 5.1e-101 337.7 0.0 5.1e-101 337.7 0.0 5.4 6 0 0 6 6 6 1 Kinesin motor domain Myosin_tail_1 PF01576.14 CAM66680.2 - 7.7e-14 50.4 718.5 0.00016 19.5 78.3 13.5 2 2 9 12 12 12 11 Myosin tail Cast PF10174.4 CAM66680.2 - 3.3e-13 48.6 271.1 1.6e-11 43.0 99.8 12.4 2 2 6 8 8 8 6 RIM-binding protein of the cytomatrix active zone MscS_porin PF12795.2 CAM66680.2 - 0.025 13.8 651.3 0.039 13.2 23.7 17.0 4 2 11 17 17 17 0 Mechanosensitive ion channel porin domain WD40 PF00400.27 CAM66681.1 - 0.00027 20.7 9.3 0.019 14.8 0.3 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat CSD PF00313.17 CAM66682.1 - 2.7e-11 43.0 1.9 3.7e-06 26.6 0.5 3.7 3 0 0 3 3 3 2 'Cold-shock' DNA-binding domain S1-like PF14444.1 CAM66682.1 - 0.027 14.1 4.6 0.052 13.2 0.1 2.8 3 0 0 3 3 3 0 S1-like Tub PF01167.13 CAM66683.1 - 3.9e-27 94.8 0.0 5.6e-26 91.0 0.0 2.4 3 0 0 3 3 3 1 Tub family FAD_binding_4 PF01565.18 CAM66683.1 - 0.11 11.9 1.1 0.22 10.9 0.8 1.4 1 0 0 1 1 1 0 FAD binding domain Enolase_C PF00113.17 CAM66684.1 - 1.7e-129 431.0 0.0 2.3e-129 430.5 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 CAM66684.1 - 4e-58 195.0 0.1 7e-58 194.2 0.0 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 CAM66684.1 - 4.8e-05 23.2 0.0 0.00013 21.8 0.0 1.8 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.6 CAM66684.1 - 0.00044 19.2 0.1 0.00044 19.2 0.1 1.6 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus Ras PF00071.17 CAM66685.1 - 4.2e-09 35.9 0.0 6e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAM66685.1 - 1.2e-05 25.8 0.0 1.8e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein PAP_central PF04928.12 CAM66686.1 - 4.7e-81 271.3 0.0 6.3e-81 270.9 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 CAM66686.1 - 1.2e-29 102.8 0.0 1.7e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 CAM66686.1 - 0.00036 20.8 0.0 0.0008 19.6 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain DNA_pol_B_palm PF14792.1 CAM66686.1 - 0.0031 17.5 0.0 0.0074 16.3 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm Macoilin PF09726.4 CAM66686.1 - 7 4.7 8.2 11 4.2 5.7 1.2 1 0 0 1 1 1 0 Transmembrane protein YjeF_N PF03853.10 CAM66687.1 - 1.1e-47 161.7 1.2 2.1e-47 160.8 0.0 2.1 2 1 1 3 3 3 1 YjeF-related protein N-terminus Carb_kinase PF01256.12 CAM66687.1 - 1.5e-46 158.7 7.5 1.5e-46 158.7 5.2 1.5 2 0 0 2 2 2 1 Carbohydrate kinase PSS PF03034.10 CAM66688.1 - 4.5e-111 370.7 12.0 6.7e-111 370.1 8.3 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase DUF4381 PF14316.1 CAM66688.1 - 5.2 7.1 12.4 3.8 7.6 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4381) NIF PF03031.13 CAM66689.1 - 1e-15 57.7 0.0 1.1e-06 28.3 0.1 2.1 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase HAD_2 PF13419.1 CAM66689.1 - 0.015 15.5 0.0 0.57 10.3 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF3829 PF12889.2 CAM66690.1 - 0.0032 16.7 6.7 0.12 11.5 0.8 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF3829) Lectin_N PF03954.9 CAM66690.1 - 0.024 14.0 3.7 1.7 8.0 0.4 3.4 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain DivIC PF04977.10 CAM66690.1 - 1.6 8.2 17.7 1.8 8.1 0.2 5.3 4 1 0 4 4 4 0 Septum formation initiator DASH_Spc34 PF08657.5 CAM66690.1 - 1.6 8.2 7.3 5.3 6.6 0.5 2.9 2 1 0 2 2 2 0 DASH complex subunit Spc34 Bap31 PF05529.7 CAM66690.1 - 1.6 8.1 9.1 7.1 6.0 0.2 3.9 3 1 1 4 4 4 0 B-cell receptor-associated protein 31-like HTH_1 PF00126.22 CAM66691.1 - 0.12 12.1 4.9 0.35 10.6 0.2 3.2 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_37 PF13744.1 CAM66692.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Ribosomal_S27 PF01599.14 CAM66695.1 - 1.5e-20 72.7 3.5 3.1e-20 71.7 2.5 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 CAM66695.1 - 2e-07 30.5 0.0 2.1e-06 27.2 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CAM66695.1 - 4.7e-07 29.0 0.0 1.3e-05 24.4 0.0 2.7 2 1 0 2 2 2 1 Ubiquitin family IBR PF01485.16 CAM66695.1 - 0.0022 17.7 0.8 0.0037 17.1 0.6 1.4 1 0 0 1 1 1 1 IBR domain F420_oxidored PF03807.12 CAM66696.1 - 4.4e-06 27.0 0.0 1.8e-05 25.0 0.0 2.1 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.12 CAM66696.1 - 0.096 11.5 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase Pkinase PF00069.20 CAM66698.1 - 1.7e-62 210.9 0.0 5.3e-62 209.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM66698.1 - 1.1e-35 123.0 0.0 2.9e-33 115.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CAM66698.1 - 0.12 12.0 0.0 0.54 9.9 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 CAM66698.1 - 0.19 10.7 0.0 0.34 9.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CAM66698.1 - 0.2 10.5 0.0 0.35 9.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like SHMT PF00464.14 CAM66700.1 - 7.8e-175 581.0 0.0 9.3e-175 580.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 CAM66700.1 - 0.0042 16.2 0.0 0.0095 15.1 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase WD40 PF00400.27 CAM66700.1 - 0.052 13.4 0.0 0.19 11.6 0.0 2.1 2 1 0 2 2 2 0 WD domain, G-beta repeat DnaJ PF00226.26 CAM66701.1 - 4.6e-20 71.1 6.6 7.9e-20 70.3 2.9 2.5 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.1 CAM66701.1 - 2.1e-11 43.2 12.6 4.6e-06 26.1 1.3 5.0 4 1 1 5 5 5 4 TPR repeat TPR_16 PF13432.1 CAM66701.1 - 7.5e-11 42.4 25.2 0.00019 22.0 1.9 5.2 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 CAM66701.1 - 6.9e-10 39.1 23.6 0.0053 17.0 0.7 6.1 4 3 2 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 CAM66701.1 - 0.00014 21.3 2.1 7 6.6 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 CAM66701.1 - 0.00027 20.4 4.2 0.94 9.1 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 CAM66701.1 - 0.00028 20.7 11.0 0.033 14.1 0.5 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 CAM66701.1 - 0.00075 19.2 14.7 0.98 9.5 0.5 5.1 5 0 0 5 5 4 3 Tetratricopeptide repeat Mhr1 PF12829.2 CAM66701.1 - 0.037 13.8 0.6 1.5 8.7 0.2 2.7 2 0 0 2 2 2 0 Transcriptional regulation of mitochondrial recombination TPR_6 PF13174.1 CAM66701.1 - 0.065 13.7 14.5 22 5.7 0.3 7.7 9 0 0 9 9 9 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CAM66701.1 - 0.23 11.3 3.1 0.53 10.2 0.2 2.9 2 2 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.1 CAM66701.1 - 0.68 10.7 33.6 1.8 9.3 0.2 8.0 5 3 5 10 10 9 0 Tetratricopeptide repeat TPR_9 PF13371.1 CAM66701.1 - 0.96 9.3 21.5 0.17 11.7 0.3 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat GRP PF07172.6 CAM66701.1 - 2.7 8.5 8.2 7.2 7.1 5.7 1.8 1 0 0 1 1 1 0 Glycine rich protein family TPR_17 PF13431.1 CAM66701.1 - 3.6 8.0 8.5 31 5.0 0.1 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 CAM66701.1 - 4 7.6 7.7 4.3 7.5 0.4 3.2 2 1 1 3 3 3 0 Alkyl sulfatase dimerisation FA_desaturase PF00487.19 CAM66702.1 - 5.3e-38 130.9 10.1 5.3e-38 130.9 7.0 1.7 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 CAM66702.1 - 2.8e-05 23.8 0.0 7.2e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_5 PF07994.7 CAM66705.1 - 1.2e-93 313.9 0.1 1.3e-93 313.7 0.1 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 CAM66705.1 - 2.9e-45 152.6 0.1 4.6e-45 152.0 0.0 1.3 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase UPF0004 PF00919.15 CAM66705.1 - 0.053 13.3 1.3 7.2 6.5 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized protein family UPF0004 tRNA-synt_1b PF00579.20 CAM66706.1 - 1.1e-53 182.2 0.0 1.6e-47 162.0 0.0 2.7 2 1 0 2 2 2 2 tRNA synthetases class I (W and Y) EMP24_GP25L PF01105.19 CAM66708.1 - 2.1e-22 79.7 0.1 2.5e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF3142 PF11340.3 CAM66708.1 - 0.025 14.2 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) DUF1772 PF08592.6 CAM66708.1 - 0.13 12.0 1.4 0.64 9.7 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) DUF3784 PF12650.2 CAM66709.1 - 0.087 12.7 1.7 0.12 12.2 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) Galactosyl_T PF01762.16 CAM66710.2 - 0.0012 18.4 1.0 0.0057 16.2 0.0 2.6 3 1 0 3 3 3 1 Galactosyltransferase Pkinase PF00069.20 CAM66711.1 - 5.8e-67 225.5 0.0 7.2e-67 225.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM66711.1 - 1.7e-44 151.8 0.0 2.2e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM66711.1 - 7.6e-09 34.9 0.1 2.5e-07 29.9 0.0 2.1 2 0 0 2 2 2 2 Kinase-like WD40 PF00400.27 CAM66713.2 - 4.5e-06 26.3 13.2 0.76 9.7 0.0 6.9 8 0 0 8 8 8 3 WD domain, G-beta repeat Reo_sigmaC PF04582.7 CAM66713.2 - 0.28 10.3 7.4 0.26 10.4 0.3 2.9 3 0 0 3 3 3 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 CAM66713.2 - 3.6 5.9 16.1 2.4 6.5 0.2 3.6 3 0 0 3 3 3 0 AAA domain C2 PF00168.25 CAM66714.1 - 0.038 13.8 0.1 8.2 6.3 0.0 2.5 2 0 0 2 2 2 0 C2 domain Vac14_Fig4_bd PF11916.3 CAM66715.1 - 1.6e-52 177.3 1.6 2.8e-52 176.4 1.1 1.4 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 CAM66715.1 - 1.3e-08 35.1 0.0 2.3e-07 31.1 0.0 2.5 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 CAM66715.1 - 0.004 17.1 7.9 0.016 15.2 0.0 4.1 4 0 0 4 4 4 1 HEAT repeat MPC PF03650.8 CAM66716.1 - 2.1e-11 43.8 0.2 2.5e-11 43.5 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) DUF3481 PF11980.3 CAM66716.1 - 0.17 11.7 0.7 0.42 10.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3481) Ten_N PF06484.7 CAM66717.1 - 0.024 13.7 0.1 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 Teneurin Intracellular Region MalF_P2 PF14785.1 CAM66717.1 - 0.11 12.3 0.9 0.24 11.2 0.1 1.9 2 0 0 2 2 2 0 Maltose transport system permease protein MalF P2 domain GST_N_3 PF13417.1 CAM66718.1 - 3.6e-08 33.5 0.0 7.4e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 CAM66718.1 - 1.8e-07 30.9 0.6 4.1e-07 29.8 0.2 1.7 2 0 0 2 2 2 1 Glutaredoxin GST_C_3 PF14497.1 CAM66718.1 - 0.0045 17.4 0.0 0.0077 16.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 CAM66718.1 - 0.0096 15.8 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Syja_N PF02383.13 CAM66719.1 - 8e-21 74.1 0.0 1.3e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain Histone PF00125.19 CAM66721.1 - 3.7e-14 52.5 0.8 4.5e-14 52.3 0.6 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CAM66721.1 - 2.6e-05 24.1 0.1 4.3e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 CAM66721.1 - 7.4e-05 22.6 0.1 0.00011 22.0 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.8 CAM66721.1 - 0.00064 19.4 0.0 0.00081 19.0 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 CAM66721.1 - 0.0013 18.5 0.0 0.0014 18.4 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit PCP_red PF08369.5 CAM66721.1 - 0.033 14.0 1.0 0.064 13.1 0.3 1.9 2 1 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit FbpA PF05833.6 CAM66721.1 - 0.049 12.1 0.0 0.057 11.9 0.0 1.0 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF4400 PF14348.1 CAM66721.1 - 0.092 12.1 0.3 0.13 11.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) Lipase_GDSL_2 PF13472.1 CAM66722.1 - 0.43 10.6 4.3 0.34 11.0 1.5 1.8 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family GDA1_CD39 PF01150.12 CAM66723.1 - 6.6e-76 255.5 0.0 1.2e-75 254.6 0.0 1.3 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 CAM66723.1 - 0.005 16.0 0.0 0.0072 15.5 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Lysine_decarbox PF03641.9 CAM66724.1 - 4.2e-24 84.8 0.0 8.6e-24 83.8 0.0 1.5 1 0 0 1 1 1 1 Possible lysine decarboxylase Med16 PF11635.3 CAM66724.1 - 0.036 12.0 0.1 0.048 11.6 0.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 16 NAD_binding_1 PF00175.16 CAM66725.1 - 6e-27 94.3 0.0 9.5e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CAM66725.1 - 1.3e-24 86.1 0.0 2.3e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 CAM66725.1 - 3.2e-07 30.3 0.0 2.5e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 CAM66725.1 - 0.017 15.1 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain DUF1191 PF06697.7 CAM66725.1 - 0.048 12.4 0.0 0.064 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) MIF4G PF02854.14 CAM66726.1 - 5.9e-24 84.6 0.9 1.1e-23 83.7 0.6 1.5 1 0 0 1 1 1 1 MIF4G domain CRM1_C PF08767.6 CAM66726.1 - 0.00024 20.1 0.0 0.0011 17.9 0.0 2.1 2 0 0 2 2 2 1 CRM1 C terminal IMS PF00817.15 CAM66726.1 - 0.012 15.3 0.1 0.53 10.0 0.1 2.5 1 1 0 1 1 1 0 impB/mucB/samB family FACT-Spt16_Nlob PF14826.1 CAM66728.1 - 0.07 12.6 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 FACT complex subunit SPT16 N-terminal lobe domain AAA_2 PF07724.9 CAM66729.1 - 3.7e-40 137.6 2.0 1.4e-31 109.7 0.6 2.8 1 1 1 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 CAM66729.1 - 1.3e-13 51.2 0.0 5.4e-06 26.6 0.0 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CAM66729.1 - 7.7e-09 35.3 0.4 2e-05 24.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CAM66729.1 - 4e-06 26.9 0.0 0.00055 20.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CAM66729.1 - 5.7e-06 27.1 0.1 3.1e-05 24.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CAM66729.1 - 3.3e-05 24.1 0.3 0.00013 22.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain ClpB_D2-small PF10431.4 CAM66729.1 - 3.5e-05 23.5 0.6 0.00023 20.9 0.0 2.5 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 CAM66729.1 - 6.9e-05 22.9 0.1 0.00033 20.7 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.16 CAM66729.1 - 8.4e-05 21.8 0.1 0.002 17.3 0.0 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI MCM PF00493.18 CAM66729.1 - 0.00025 19.9 0.8 0.01 14.6 0.0 2.5 2 1 0 2 2 2 1 MCM2/3/5 family TIP49 PF06068.8 CAM66729.1 - 0.00039 19.2 0.0 0.0011 17.8 0.0 1.7 1 0 0 1 1 1 1 TIP49 C-terminus NTPase_1 PF03266.10 CAM66729.1 - 0.0014 18.3 0.7 0.52 9.9 0.0 2.6 2 0 0 2 2 2 1 NTPase AAA_14 PF13173.1 CAM66729.1 - 0.0017 18.2 0.0 2.1 8.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 CAM66729.1 - 0.0019 17.2 0.1 0.019 14.0 0.0 2.3 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 CAM66729.1 - 0.0035 16.4 0.0 0.0096 15.0 0.0 1.7 1 1 0 1 1 1 1 Zeta toxin DEAD PF00270.24 CAM66729.1 - 0.004 16.6 0.0 0.36 10.3 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_33 PF13671.1 CAM66729.1 - 0.0057 16.5 0.0 0.017 15.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CAM66729.1 - 0.014 14.7 0.0 0.033 13.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.1 CAM66729.1 - 0.015 15.2 0.1 0.091 12.7 0.0 2.3 2 1 1 3 3 3 0 AAA domain Sigma54_activat PF00158.21 CAM66729.1 - 0.017 14.6 0.0 0.053 12.9 0.0 1.8 2 0 0 2 2 1 0 Sigma-54 interaction domain CPT PF07931.7 CAM66729.1 - 0.025 14.1 0.2 0.21 11.1 0.0 2.5 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.22 CAM66729.1 - 0.042 14.1 0.1 0.096 12.9 0.1 1.6 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 CAM66729.1 - 0.046 12.9 0.0 0.081 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 UPF0079 PF02367.12 CAM66729.1 - 0.046 13.3 0.0 0.34 10.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ATP-synt_ab PF00006.20 CAM66729.1 - 0.086 12.3 0.0 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.17 CAM66729.1 - 0.11 12.7 0.0 0.72 10.0 0.0 2.3 2 1 0 2 2 2 0 RNA helicase NACHT PF05729.7 CAM66729.1 - 0.12 12.0 0.1 2.5 7.7 0.0 2.6 2 1 0 2 2 2 0 NACHT domain FMO-like PF00743.14 CAM66730.1 - 5e-27 94.3 0.1 2.3e-22 78.9 0.1 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 CAM66730.1 - 2.4e-17 63.6 0.0 5.7e-17 62.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CAM66730.1 - 9.8e-11 41.8 0.0 1.7e-09 37.8 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CAM66730.1 - 8.2e-09 34.8 0.4 1.8e-06 27.1 0.2 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 CAM66730.1 - 9.1e-06 25.6 0.0 3.6e-05 23.6 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 CAM66730.1 - 0.00015 21.5 0.1 0.00062 19.5 0.0 2.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 CAM66730.1 - 0.00075 19.8 0.0 1.8 9.0 0.0 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.7 CAM66730.1 - 0.0031 16.8 0.0 0.45 9.8 0.0 2.5 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain DUF1490 PF07371.7 CAM66730.1 - 0.0059 16.5 0.5 0.0059 16.5 0.3 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1490) HI0933_like PF03486.9 CAM66730.1 - 0.02 13.3 0.1 0.032 12.7 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 CAM66730.1 - 0.021 13.7 0.0 0.033 13.1 0.0 1.4 1 1 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 CAM66730.1 - 0.09 11.6 1.5 0.16 10.8 0.1 2.1 2 1 0 2 2 2 0 FAD binding domain AlaDh_PNT_C PF01262.16 CAM66730.1 - 0.1 12.1 0.0 3.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 CAM66730.1 - 0.15 10.9 0.1 0.94 8.2 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A YlqD PF11068.3 CAM66731.1 - 0.54 10.2 2.4 0.98 9.4 1.7 1.3 1 0 0 1 1 1 0 YlqD protein Adeno_PIX PF03955.9 CAM66731.1 - 1.9 9.0 12.5 0.2 12.1 3.0 2.8 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Mito_carr PF00153.22 CAM66732.1 - 8.3e-44 147.2 1.2 7.7e-17 60.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DEAD PF00270.24 CAM66733.1 - 5.8e-42 143.0 0.2 1.1e-41 142.1 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM66733.1 - 1.5e-21 76.0 0.0 7.3e-21 73.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CAM66733.1 - 0.091 12.9 0.6 1.9 8.6 0.1 3.0 2 1 0 2 2 2 0 AAA domain zf-CCCH PF00642.19 CAM66734.1 - 1.4e-05 24.6 6.8 1.4e-05 24.6 4.7 2.4 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MAGE_N PF12440.3 CAM66734.1 - 0.05 13.8 2.8 0.11 12.8 2.0 1.6 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal Auxin_repressed PF05564.7 CAM66734.1 - 0.14 12.8 3.0 0.3 11.7 2.1 1.6 1 1 0 1 1 1 0 Dormancy/auxin associated protein oligo_HPY PF08352.7 CAM66734.1 - 0.24 11.7 5.6 0.83 10.0 0.6 2.6 2 0 0 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region zf-CCCH PF00642.19 CAM66736.1 - 9.5e-05 21.9 4.1 0.00016 21.2 2.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CAM66736.1 - 0.1 12.6 2.4 0.23 11.4 1.7 1.7 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type PP2C PF00481.16 CAM66737.1 - 2.5e-63 213.8 0.0 4.3e-63 213.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CAM66737.1 - 1.7e-05 24.3 0.0 5e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C Pkinase PF00069.20 CAM66738.1 - 6.3e-47 159.8 0.0 1.6e-46 158.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM66738.1 - 1.5e-14 53.6 0.0 3.6e-14 52.4 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CAM66738.1 - 0.00018 21.2 0.1 0.0013 18.5 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CAM66738.1 - 0.0017 17.9 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 CAM66738.1 - 0.13 11.0 0.1 0.21 10.3 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PIP49_C PF12260.3 CAM66738.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Cyt-b5 PF00173.23 CAM66740.1 - 2.4e-06 27.2 0.0 3.2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Adeno_E3_CR2 PF02439.10 CAM66740.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF2422 PF10337.4 CAM66740.1 - 0.12 11.1 0.1 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Ribosomal_L13 PF00572.13 CAM66742.1 - 4e-22 78.6 1.1 5.7e-22 78.1 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L13 DUF4455 PF14643.1 CAM66742.1 - 0.014 14.0 2.5 0.019 13.6 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) Milton PF12448.3 CAM66743.1 - 0.015 15.4 0.8 0.036 14.2 0.6 1.7 1 0 0 1 1 1 0 Kinesin associated protein Metallophos PF00149.23 CAM66744.1 - 4.5e-28 98.0 0.0 7.1e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase WD40 PF00400.27 CAM66746.1 - 7.1e-12 44.7 9.4 2.2e-06 27.2 0.0 5.6 6 0 0 6 6 6 5 WD domain, G-beta repeat tRNA-synt_2 PF00152.15 CAM66747.1 - 1.8e-87 293.2 0.0 3e-87 292.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CAM66747.1 - 5e-13 48.7 0.0 1.2e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CAM66747.1 - 7.5e-07 28.5 0.0 0.0059 15.8 0.0 2.7 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 CAM66747.1 - 0.00017 21.2 0.1 0.052 13.1 0.0 3.1 3 0 0 3 3 3 1 tRNA synthetase class II core domain (G, H, P, S and T) FlxA PF14282.1 CAM66747.1 - 0.18 11.7 1.7 0.38 10.7 1.2 1.5 1 0 0 1 1 1 0 FlxA-like protein Histone_HNS PF00816.16 CAM66747.1 - 0.4 11.2 2.4 0.91 10.0 1.6 1.5 1 0 0 1 1 1 0 H-NS histone family Seryl_tRNA_N PF02403.17 CAM66747.1 - 8.9 6.3 7.4 1.7 8.6 2.4 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FAE1_CUT1_RppA PF08392.7 CAM66748.1 - 0.0078 15.3 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein LMWSLP_N PF12211.3 CAM66749.1 - 0.36 10.6 6.9 0.063 13.1 1.4 2.1 2 0 0 2 2 2 0 Low molecular weight S layer protein N terminal ERM PF00769.14 CAM66750.1 - 0.036 13.6 11.9 0.054 13.0 8.3 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family RPA_C PF08784.6 CAM66751.1 - 1.7e-14 54.0 1.1 2.6e-14 53.4 0.2 1.8 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 CAM66751.1 - 9.2e-09 35.0 0.0 1.6e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain GntR PF00392.16 CAM66751.1 - 0.081 12.3 0.0 0.19 11.1 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family PaaX PF07848.7 CAM66751.1 - 0.086 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 PaaX-like protein PPR_2 PF13041.1 CAM66752.1 - 7.8e-07 28.9 0.6 0.019 14.8 0.0 2.4 2 0 0 2 2 2 2 PPR repeat family RPM2 PF08579.6 CAM66752.1 - 0.022 14.8 0.0 0.032 14.3 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) DUF4241 PF14025.1 CAM66752.1 - 0.031 14.0 0.9 0.42 10.3 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4241) Prefoldin_2 PF01920.15 CAM66752.1 - 0.047 13.4 0.4 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 Prefoldin subunit PPR_2 PF13041.1 CAM66753.1 - 7.4e-07 29.0 0.5 0.019 14.8 0.0 2.4 2 0 0 2 2 2 2 PPR repeat family RPM2 PF08579.6 CAM66753.1 - 0.022 14.8 0.0 0.032 14.3 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) Prefoldin_2 PF01920.15 CAM66753.1 - 0.047 13.4 0.5 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 Prefoldin subunit DUF4241 PF14025.1 CAM66753.1 - 0.048 13.4 0.9 0.43 10.3 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4241) DUF3081 PF11280.3 CAM66754.1 - 0.053 13.0 0.0 0.3 10.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3081) Ecotin PF03974.8 CAM66755.1 - 5.7e-40 135.9 0.0 6.8e-40 135.7 0.0 1.0 1 0 0 1 1 1 1 Ecotin Abhydrolase_3 PF07859.8 CAM66757.1 - 4.4e-12 46.0 0.1 1.2e-11 44.5 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CAM66757.1 - 7.2e-11 42.0 0.0 2.1e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 CAM66757.1 - 8.1e-11 41.3 0.1 1.9e-10 40.0 0.0 1.6 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_6 PF12697.2 CAM66757.1 - 5.3e-08 33.0 0.9 1.2e-07 31.9 0.0 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CAM66757.1 - 2.8e-06 26.6 0.2 0.0067 15.6 0.1 2.9 2 1 0 2 2 2 2 Prolyl oligopeptidase family DUF4566 PF15130.1 CAM66757.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4566) Abhydrolase_3 PF07859.8 CAM66758.1 - 1e-11 44.8 0.6 2e-11 43.8 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CAM66758.1 - 3.6e-10 39.7 0.2 1.9e-09 37.3 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family COesterase PF00135.23 CAM66758.1 - 9.8e-10 37.7 0.0 1.5e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 CAM66758.1 - 1.4e-06 27.7 0.1 0.0089 15.2 0.1 2.6 2 1 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 CAM66758.1 - 0.035 12.9 0.0 0.057 12.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Ribosomal_L4 PF00573.17 CAM66759.1 - 0.0089 15.4 1.6 0.02 14.2 1.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family PseudoU_synth_2 PF00849.17 CAM66761.1 - 4.2e-17 62.4 2.0 3.5e-08 33.4 0.2 2.8 2 1 0 2 2 2 2 RNA pseudouridylate synthase Ribosomal_60s PF00428.14 CAM66762.1 - 6.2e-20 71.3 15.4 7.6e-20 71.1 10.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Arg_repressor_C PF02863.13 CAM66762.1 - 0.02 14.3 0.1 0.02 14.3 0.1 1.9 2 0 0 2 2 2 0 Arginine repressor, C-terminal domain 3HBOH PF10605.4 CAM66762.1 - 0.061 11.4 8.3 0.065 11.3 5.7 1.0 1 0 0 1 1 1 0 3HB-oligomer hydrolase (3HBOH) Jun PF03957.8 CAM66762.1 - 0.29 10.8 7.0 0.34 10.5 4.9 1.1 1 0 0 1 1 1 0 Jun-like transcription factor DUF3138 PF11336.3 CAM66762.1 - 5.4 5.0 9.6 5.6 5.0 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Ribosomal_60s PF00428.14 CAM66763.1 - 6.2e-20 71.3 15.4 7.6e-20 71.1 10.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Arg_repressor_C PF02863.13 CAM66763.1 - 0.02 14.3 0.1 0.02 14.3 0.1 1.9 2 0 0 2 2 2 0 Arginine repressor, C-terminal domain 3HBOH PF10605.4 CAM66763.1 - 0.061 11.4 8.3 0.065 11.3 5.7 1.0 1 0 0 1 1 1 0 3HB-oligomer hydrolase (3HBOH) Jun PF03957.8 CAM66763.1 - 0.29 10.8 7.0 0.34 10.5 4.9 1.1 1 0 0 1 1 1 0 Jun-like transcription factor DUF3138 PF11336.3 CAM66763.1 - 5.4 5.0 9.6 5.6 5.0 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Asparaginase PF00710.15 CAM66764.1 - 1.6e-68 230.9 0.0 3.7e-61 206.7 0.0 2.0 2 0 0 2 2 2 2 Asparaginase DUF282 PF03380.9 CAM66764.1 - 0.0021 17.7 2.0 1.8 8.3 0.0 3.1 3 0 0 3 3 3 2 Caenorhabditis protein of unknown function, DUF282 PPR_2 PF13041.1 CAM66766.1 - 0.0013 18.6 0.0 0.083 12.8 0.0 2.5 1 1 1 2 2 2 1 PPR repeat family Neogenin_C PF06583.7 CAM66766.1 - 0.057 12.9 0.3 3.9 6.9 0.0 2.2 2 0 0 2 2 2 0 Neogenin C-terminus PPR_3 PF13812.1 CAM66766.1 - 0.61 10.5 4.4 19 5.8 0.0 4.5 5 1 0 5 5 5 0 Pentatricopeptide repeat domain FR47 PF08445.5 CAM66768.1 - 0.068 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein FadA PF09403.5 CAM66772.1 - 0.089 12.8 3.5 0.18 11.8 2.4 1.4 1 0 0 1 1 1 0 Adhesion protein FadA NinG PF05766.7 CAM66772.1 - 0.094 12.4 0.3 0.16 11.6 0.2 1.2 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein AAA PF00004.24 CAM66773.1 - 4.2e-39 133.7 0.0 7.1e-39 133.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 CAM66773.1 - 5.9e-06 26.0 0.0 1.6e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.7 CAM66773.1 - 8.5e-06 24.9 0.0 1.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 CAM66773.1 - 1.5e-05 24.7 0.0 0.00013 21.7 0.1 2.6 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CAM66773.1 - 1.6e-05 25.0 0.4 0.002 18.2 0.0 3.2 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 CAM66773.1 - 0.00011 23.0 0.0 0.00021 22.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CAM66773.1 - 0.00018 21.2 0.3 0.0019 17.9 0.0 2.8 2 1 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 CAM66773.1 - 0.00039 19.8 0.2 0.089 12.1 0.0 2.4 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CAM66773.1 - 0.00087 18.7 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 CAM66773.1 - 0.0011 18.9 0.9 0.017 15.0 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain TIP49 PF06068.8 CAM66773.1 - 0.0029 16.3 0.0 0.0053 15.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_2 PF07724.9 CAM66773.1 - 0.0043 16.9 0.0 0.0076 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 CAM66773.1 - 0.0046 16.1 0.1 0.011 14.9 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 CAM66773.1 - 0.01 15.7 0.1 0.036 13.9 0.0 2.1 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.7 CAM66773.1 - 0.028 13.5 0.0 0.05 12.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF815 PF05673.8 CAM66773.1 - 0.041 12.8 0.0 0.082 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 CAM66773.1 - 0.042 13.7 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CAM66773.1 - 0.1 12.9 0.9 0.14 12.5 0.0 1.7 2 0 0 2 2 1 0 AAA domain Parvo_NS1 PF01057.12 CAM66773.1 - 0.11 11.4 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.7 CAM66773.1 - 0.11 12.1 0.0 0.5 10.0 0.0 2.0 1 1 1 2 2 2 0 NACHT domain RNA_helicase PF00910.17 CAM66773.1 - 0.12 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Ecotin PF03974.8 CAM66774.1 - 8.2e-42 141.9 0.0 9.7e-42 141.7 0.0 1.0 1 0 0 1 1 1 1 Ecotin DUF4136 PF13590.1 CAM66774.1 - 0.073 13.1 0.4 0.13 12.3 0.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4136) Ecotin PF03974.8 CAM66775.1 - 1.6e-36 124.8 0.1 3.6e-36 123.7 0.1 1.6 2 0 0 2 2 2 1 Ecotin DUF3633 PF12315.3 CAM66775.1 - 0.65 9.2 3.8 5.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3633) AAA_13 PF13166.1 CAM66779.1 - 0.41 9.0 5.1 0.044 12.2 0.3 1.7 2 0 0 2 2 2 0 AAA domain Atg14 PF10186.4 CAM66779.1 - 1.2 8.0 22.4 0.025 13.5 6.9 3.4 5 0 0 5 5 5 0 UV radiation resistance protein and autophagy-related subunit 14 TBPIP PF07106.8 CAM66779.1 - 3.3 7.2 11.7 0.084 12.4 2.2 2.5 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) RasGAP_C PF03836.10 CAM66779.1 - 3.6 7.2 8.8 0.16 11.6 1.3 2.2 3 0 0 3 3 3 0 RasGAP C-terminus SPC22 PF04573.7 CAM66781.1 - 4.7e-10 38.9 0.1 9.8e-07 28.1 0.0 3.1 3 0 0 3 3 3 3 Signal peptidase subunit MDH PF02315.11 CAM66782.1 - 0.015 15.1 0.1 0.033 14.0 0.1 1.6 1 0 0 1 1 1 0 Methanol dehydrogenase beta subunit Filament PF00038.16 CAM66783.1 - 0.67 9.3 8.5 2.8 7.3 1.1 2.4 2 0 0 2 2 2 0 Intermediate filament protein IncA PF04156.9 CAM66783.1 - 0.69 9.4 13.5 0.34 10.4 0.1 2.7 3 0 0 3 3 3 0 IncA protein Prominin PF05478.6 CAM66783.1 - 1.2 6.5 0.1 1.9 5.9 0.1 1.1 1 0 0 1 1 1 0 Prominin TPR_MLP1_2 PF07926.7 CAM66783.1 - 8.6 6.1 12.5 0.33 10.6 1.9 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein CompInhib_SCIN PF11546.3 CAM66786.2 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Staphylococcal complement inhibitor SCIN DUF842 PF05811.8 CAM66787.1 - 0.17 11.3 4.1 0.087 12.2 1.1 1.8 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) Kelch_4 PF13418.1 CAM66788.2 - 8.9e-25 86.2 7.9 1.1e-08 34.6 0.1 6.7 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 CAM66788.2 - 9e-20 70.2 1.3 0.00027 20.8 0.0 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.1 CAM66788.2 - 3.3e-18 65.3 12.8 0.00012 22.1 0.0 7.6 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.1 CAM66788.2 - 3.2e-14 52.3 3.3 1.2e-06 28.3 0.1 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 CAM66788.2 - 1.6e-12 46.6 3.7 0.00018 21.0 0.0 4.3 3 0 0 3 3 3 3 Kelch motif Kelch_1 PF01344.20 CAM66788.2 - 4.4e-09 35.7 5.0 0.0021 17.5 0.1 4.0 4 0 0 4 4 4 2 Kelch motif Cmc1 PF08583.5 CAM66792.1 - 0.0067 16.1 0.9 0.0067 16.1 0.6 1.9 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like Snurportin1 PF11538.3 CAM66792.1 - 0.045 13.5 0.4 10 5.9 0.0 2.9 2 0 0 2 2 2 0 Snurportin1 UPF0203 PF05254.7 CAM66792.1 - 0.064 13.1 0.7 0.064 13.1 0.5 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) TfoX_N PF04993.8 CAM66792.1 - 0.12 12.2 1.3 0.26 11.1 0.0 2.1 2 1 0 2 2 2 0 TfoX N-terminal domain tRNA-synt_2c PF01411.14 CAM66793.1 - 0.0026 16.1 0.0 0.0038 15.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 CAM66793.1 - 0.0041 16.9 0.2 0.017 14.9 0.0 2.1 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain Tim54 PF11711.3 CAM66794.2 - 0.088 11.3 0.2 0.15 10.6 0.1 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FAD_binding_3 PF01494.14 CAM66796.1 - 1.1e-05 24.6 3.6 1.5 7.8 0.0 4.1 3 1 0 3 3 3 3 FAD binding domain DAO PF01266.19 CAM66796.1 - 7.8e-05 21.7 0.1 0.00027 19.9 0.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 CAM66796.1 - 0.0013 19.0 0.0 0.0032 17.8 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 CAM66796.1 - 0.06 12.7 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 CAM66796.1 - 0.15 11.6 0.1 0.29 10.7 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_16 PF10294.4 CAM66797.1 - 2.8e-09 36.6 0.1 4.1e-06 26.3 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 CAM66797.1 - 3.1e-05 24.5 0.1 5.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CAM66797.1 - 0.063 12.3 0.0 0.094 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 CAM66797.1 - 0.08 12.9 0.1 0.21 11.6 0.1 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 CAM66797.1 - 0.11 12.8 0.2 0.31 11.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain DUF2871 PF11070.3 CAM66798.1 - 7.1e-47 158.8 11.6 9.1e-47 158.5 8.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2871) Plant_vir_prot PF01307.12 CAM66798.1 - 0.028 14.1 0.2 3 7.5 0.0 2.5 3 0 0 3 3 3 0 Plant viral movement protein Pkinase PF00069.20 CAM66801.1 - 2.4e-29 102.2 0.0 3.6e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM66801.1 - 7.5e-15 54.6 0.0 1.1e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM66801.1 - 0.00013 21.0 0.0 0.0002 20.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CAM66801.1 - 0.0082 15.9 0.1 3 7.5 0.0 2.5 1 1 0 2 2 2 2 Phosphotransferase enzyme family KRE9 PF05390.6 CAM66801.1 - 0.11 12.8 3.1 9.4 6.6 0.1 3.1 3 0 0 3 3 3 0 Yeast cell wall synthesis protein KRE9/KNH1 PAT1 PF09770.4 CAM66801.1 - 6.6 4.8 25.0 10 4.1 17.4 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2031 PF09592.5 CAM66804.2 - 0.044 12.9 2.5 0.1 11.7 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) Pex16 PF08610.5 CAM66805.1 - 1.9e-22 79.7 0.4 2.2e-19 69.6 0.1 2.2 2 0 0 2 2 2 2 Peroxisomal membrane protein (Pex16) DPM2 PF07297.7 CAM66806.1 - 2.1e-17 63.1 1.0 2.8e-17 62.7 0.7 1.1 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) GDI PF00996.13 CAM66807.1 - 1.1e-31 109.5 0.0 4.1e-20 71.5 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor Methyltransf_16 PF10294.4 CAM66807.1 - 4.7e-13 48.9 0.0 4.4e-06 26.2 0.0 2.3 1 1 1 2 2 2 2 Putative methyltransferase MTS PF05175.9 CAM66807.1 - 0.0027 17.1 0.1 1 8.7 0.0 2.6 1 1 1 2 2 2 2 Methyltransferase small domain Methyltransf_18 PF12847.2 CAM66807.1 - 0.026 15.1 0.1 0.11 13.0 0.0 2.2 1 0 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 CAM66807.1 - 0.036 13.0 0.0 0.093 11.6 0.0 1.7 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Nuc_sug_transp PF04142.10 CAM66810.1 - 8e-24 84.0 16.7 1.7e-21 76.4 11.5 3.3 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 CAM66810.1 - 7.9e-05 22.7 27.6 0.012 15.6 2.5 3.4 3 1 1 4 4 4 2 EamA-like transporter family TPT PF03151.11 CAM66810.1 - 0.00059 19.5 19.3 0.031 13.9 5.7 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family Mito_fiss_reg PF05308.6 CAM66811.1 - 0.093 12.0 1.3 0.23 10.7 0.9 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator MFS_1 PF07690.11 CAM66813.1 - 2.4e-11 42.9 44.8 5.1e-07 28.7 8.9 3.8 2 2 2 4 4 4 4 Major Facilitator Superfamily Sugar_tr PF00083.19 CAM66813.1 - 1e-06 27.6 4.1 1e-06 27.6 2.9 2.7 2 1 1 3 3 3 2 Sugar (and other) transporter DUF1228 PF06779.9 CAM66813.1 - 0.0043 17.0 3.7 0.067 13.2 0.7 3.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1228) Inositol_P PF00459.20 CAM66814.1 - 1e-46 159.4 2.0 1.2e-23 83.8 0.3 2.2 2 0 0 2 2 2 2 Inositol monophosphatase family SOBP PF15279.1 CAM66814.1 - 0.0037 17.6 2.4 0.0052 17.2 1.6 1.2 1 0 0 1 1 1 1 Sine oculis-binding protein Mito_carr PF00153.22 CAM66814.1 - 0.0074 15.9 0.1 0.036 13.7 0.1 2.3 1 1 0 1 1 1 1 Mitochondrial carrier protein ABC2_membrane PF01061.19 CAM66815.1 - 3.2e-38 130.9 19.1 5.1e-38 130.3 13.3 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 CAM66815.1 - 4.4e-19 69.1 0.0 6.8e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 CAM66815.1 - 0.00024 21.1 0.0 0.00054 19.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 CAM66815.1 - 0.00047 20.2 0.1 0.33 10.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 CAM66815.1 - 0.0051 16.0 0.0 0.01 15.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 CAM66815.1 - 0.012 15.1 0.4 0.026 14.0 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 CAM66815.1 - 0.017 15.2 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 CAM66815.1 - 0.027 13.3 0.0 0.04 12.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_23 PF13476.1 CAM66815.1 - 0.041 14.2 0.0 0.066 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 CAM66815.1 - 0.047 12.7 0.0 2.4 7.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain UPF0079 PF02367.12 CAM66815.1 - 0.05 13.2 0.1 0.19 11.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PRK PF00485.13 CAM66815.1 - 0.054 13.0 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_10 PF12846.2 CAM66815.1 - 0.062 12.7 0.2 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain NACHT PF05729.7 CAM66815.1 - 0.073 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 CAM66815.1 - 0.081 13.1 0.0 0.53 10.4 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.1 CAM66815.1 - 0.091 12.1 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 CAM66815.1 - 0.096 12.2 0.9 0.17 11.4 0.6 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CAM66815.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CAM66815.1 - 0.13 12.0 0.7 0.37 10.5 0.5 1.8 1 1 0 1 1 1 0 Part of AAA domain SMC_N PF02463.14 CAM66815.1 - 0.13 11.4 0.0 10 5.2 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 CAM66815.1 - 0.15 12.9 0.3 0.49 11.2 0.2 2.0 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 CAM66815.1 - 0.17 11.2 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 CAM66815.1 - 0.18 11.3 0.0 0.78 9.2 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC2_membrane_2 PF12679.2 CAM66815.1 - 0.23 10.2 3.8 0.42 9.4 2.7 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_24 PF13479.1 CAM66815.1 - 0.24 10.9 0.7 0.42 10.1 0.5 1.3 1 0 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.2 CAM66815.1 - 0.68 8.9 19.9 1.4 7.8 13.8 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein HEAT_2 PF13646.1 CAM66818.1 - 1.4e-22 79.7 15.3 1.5e-09 38.0 0.2 7.1 4 1 3 7 7 7 6 HEAT repeats HEAT PF02985.17 CAM66818.1 - 2e-21 74.1 25.5 0.0016 18.3 0.0 10.7 11 0 0 11 11 11 8 HEAT repeat Adaptin_N PF01602.15 CAM66818.1 - 0.00013 20.4 5.6 0.018 13.3 0.2 2.9 2 1 0 2 2 2 2 Adaptin N terminal region CLASP_N PF12348.3 CAM66818.1 - 0.0022 17.3 4.5 0.26 10.6 0.1 3.9 3 2 2 5 5 5 1 CLASP N terminal Nipped-B_C PF12830.2 CAM66818.1 - 0.0022 17.6 0.6 2.7 7.5 0.0 3.4 3 0 0 3 3 3 2 Sister chromatid cohesion C-terminus Cnd1 PF12717.2 CAM66818.1 - 0.0079 16.0 0.5 0.34 10.7 0.0 3.1 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 CAM66818.1 - 0.0088 16.4 1.1 41 4.6 0.0 5.5 4 1 4 8 8 8 0 Vacuolar 14 Fab1-binding region Arm PF00514.18 CAM66818.1 - 0.0099 15.6 3.0 4.4 7.2 0.1 4.3 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 CAM66818.1 - 0.46 11.0 22.9 15 6.2 1.8 7.3 7 1 1 8 8 8 0 HEAT-like repeat Cohesin_HEAT PF12765.2 CAM66818.1 - 1.1 9.2 4.1 0.65 10.0 0.1 2.6 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion EF-hand_9 PF14658.1 CAM66819.1 - 4.2e-09 36.2 0.0 0.011 15.5 0.0 3.3 2 1 1 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 CAM66819.1 - 4.8e-09 36.2 0.0 4.4e-05 23.5 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CAM66819.1 - 6.2e-09 35.3 0.0 0.0092 15.5 0.0 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 CAM66819.1 - 4.6e-06 26.0 0.0 0.4 10.6 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 CAM66819.1 - 0.00015 20.8 0.0 3.3 7.2 0.0 3.4 3 0 0 3 3 3 2 EF hand DUF2087 PF09860.4 CAM66819.1 - 0.0046 16.6 0.0 0.98 9.2 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2087) DUF2267 PF10025.4 CAM66819.1 - 0.017 15.1 0.4 5.3 7.1 0.1 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) UBN2 PF14223.1 CAM66819.1 - 0.068 12.9 0.0 8.5 6.1 0.0 2.3 1 1 1 2 2 2 0 gag-polypeptide of LTR copia-type MAP65_ASE1 PF03999.7 CAM66820.1 - 8.5e-08 31.2 3.2 8.5e-08 31.2 2.2 2.0 2 0 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) Nup88 PF10168.4 CAM66820.1 - 1.2 6.8 5.3 2 6.1 3.7 1.2 1 0 0 1 1 1 0 Nuclear pore component Ribosomal_S3_C PF00189.15 CAM66821.1 - 9.8e-16 57.7 1.0 9.8e-16 57.7 0.7 1.7 2 1 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 CAM66821.1 - 6.2e-09 35.2 0.2 1.5e-08 34.0 0.1 1.6 2 0 0 2 2 2 1 KH domain Evr1_Alr PF04777.8 CAM66822.1 - 2.5e-24 84.9 0.6 5.6e-24 83.8 0.4 1.6 1 0 0 1 1 1 1 Erv1 / Alr family LINES_C PF14695.1 CAM66822.1 - 0.16 11.2 0.0 1.8 7.8 0.0 2.2 2 0 0 2 2 2 0 Lines C-terminus ThiF PF00899.16 CAM66823.1 - 4.3e-34 117.2 0.0 8.4e-34 116.3 0.0 1.5 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 CAM66823.1 - 1.3e-06 27.9 0.3 4.4e-06 26.1 0.1 2.0 2 0 0 2 2 2 1 MoeZ/MoeB domain 2-Hacid_dh_C PF02826.14 CAM66823.1 - 0.0035 16.5 0.0 0.0074 15.4 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 CAM66823.1 - 0.0066 16.5 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 CAM66823.1 - 0.0094 15.4 0.1 0.033 13.6 0.1 1.9 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 CAM66823.1 - 0.054 12.5 0.3 0.054 12.5 0.2 1.7 2 0 0 2 2 2 0 FAD binding domain NAD_Gly3P_dh_N PF01210.18 CAM66823.1 - 0.06 13.0 0.0 0.096 12.4 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 CAM66823.1 - 0.073 12.4 0.1 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Rad9 PF04139.8 CAM66824.1 - 3.8e-07 29.4 0.0 4.9e-06 25.8 0.0 2.3 2 1 0 2 2 2 1 Rad9 Fer4_17 PF13534.1 CAM66825.1 - 6.1e-08 32.8 0.6 1.4e-07 31.7 0.4 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 CAM66825.1 - 3.4e-07 30.2 0.8 6.5e-07 29.2 0.6 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 CAM66825.1 - 5.4e-06 26.7 4.2 0.0011 19.3 0.1 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 CAM66825.1 - 1.2e-05 25.4 0.5 0.0035 17.5 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 CAM66825.1 - 0.00018 21.2 0.3 0.00039 20.1 0.2 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 CAM66825.1 - 0.011 16.0 2.5 0.037 14.4 1.7 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_4 PF12800.2 CAM66825.1 - 0.082 13.2 1.0 0.082 13.2 0.7 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Ribosomal_L6e PF01159.14 CAM66826.1 - 3.4e-33 114.1 0.4 1.1e-32 112.4 0.3 1.8 1 1 0 1 1 1 1 Ribosomal protein L6e KOW PF00467.24 CAM66826.1 - 0.0057 16.3 0.0 0.02 14.6 0.0 1.9 1 1 1 2 2 2 1 KOW motif OAD_gamma PF04277.8 CAM66826.1 - 2.3 8.6 10.5 0.79 10.1 2.7 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain ELFV_dehydrog PF00208.16 CAM66827.2 - 3.6e-44 151.1 0.0 6.1e-44 150.4 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 CAM66827.2 - 4.1e-18 64.3 0.0 2e-09 35.5 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase polyprenyl_synt PF00348.12 CAM66828.1 - 5e-49 166.4 0.0 7.7e-49 165.8 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase SQS_PSY PF00494.14 CAM66828.1 - 0.045 13.0 0.4 0.13 11.4 0.3 1.9 1 1 0 1 1 1 0 Squalene/phytoene synthase SKIP_SNW PF02731.10 CAM66829.1 - 2e-07 30.5 2.8 2e-07 30.5 1.9 2.6 1 1 1 2 2 2 1 SKIP/SNW domain CAF-1_p150 PF11600.3 CAM66829.1 - 5.1 6.4 30.3 0.23 10.8 17.0 1.7 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal AhpC-TSA PF00578.16 CAM66830.1 - 1.6e-38 131.2 0.0 2e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CAM66830.1 - 7.4e-17 61.2 0.0 8.6e-17 61.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CAM66830.1 - 3e-13 49.1 0.1 6.9e-13 48.0 0.1 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA PF00578.16 CAM66832.1 - 1.2e-37 128.3 0.0 1.5e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CAM66832.1 - 1.8e-16 59.9 0.0 2.1e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CAM66832.1 - 3.1e-11 42.7 0.1 7.3e-11 41.5 0.0 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA PF00578.16 CAM66834.1 - 2.1e-38 130.8 0.0 2.6e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CAM66834.1 - 6.8e-17 61.3 0.0 7.9e-17 61.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CAM66834.1 - 2.6e-13 49.3 0.3 6.9e-13 48.0 0.1 1.9 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin TF_Zn_Ribbon PF08271.7 CAM66835.1 - 1.4e-05 24.2 1.0 2.6e-05 23.4 0.7 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding DUF2387 PF09526.5 CAM66835.1 - 0.043 13.7 0.6 0.098 12.5 0.4 1.5 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) Nucleoside_tran PF01733.13 CAM66838.2 - 3.2e-34 118.5 2.9 3.2e-34 118.5 2.0 2.1 2 1 0 2 2 2 1 Nucleoside transporter UFC1 PF08694.6 CAM66839.1 - 2.2e-81 271.0 0.1 2.5e-81 270.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.21 CAM66839.1 - 0.0007 19.0 0.5 0.00095 18.6 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CAM66839.1 - 0.023 14.6 0.4 0.038 13.8 0.3 1.4 1 1 0 1 1 1 0 RWD domain Prok-E2_B PF14461.1 CAM66839.1 - 0.047 13.4 0.0 0.06 13.0 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B DUF2510 PF10708.4 CAM66839.1 - 0.98 8.9 4.6 19 4.7 1.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2510) SET PF00856.23 CAM66840.1 - 1e-07 32.4 0.1 3.9e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 SET domain HrpA_pilin PF09589.5 CAM66841.1 - 0.034 14.5 0.6 0.078 13.3 0.4 1.5 1 0 0 1 1 1 0 HrpA pilus formation protein SR-25 PF10500.4 CAM66841.1 - 1.4 8.3 8.6 0.17 11.3 1.8 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DNA_topoisoIV PF00521.15 CAM66843.1 - 1.4e-105 353.6 0.0 2.2e-105 352.9 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A Toprim PF01751.17 CAM66843.1 - 1.8e-11 43.8 0.0 5.4e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 Toprim domain DNA_gyraseB PF00204.20 CAM66843.1 - 5.2e-11 42.0 0.0 1.2e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.21 CAM66843.1 - 2.1e-07 30.6 0.0 4.8e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CAM66843.1 - 0.00012 21.7 0.1 0.0003 20.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SAB PF04382.8 CAM66843.1 - 0.017 14.7 0.1 0.05 13.2 0.1 1.7 1 0 0 1 1 1 0 SAB domain DUF3045 PF11243.3 CAM66843.1 - 0.071 13.3 0.4 0.2 11.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3045) UCH PF00443.24 CAM66844.1 - 7.1e-36 123.6 0.0 1.2e-35 122.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.3 CAM66844.1 - 7.1e-13 48.3 0.0 1.6e-05 24.2 0.0 3.1 2 1 0 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.1 CAM66844.1 - 1.2e-11 44.6 0.0 2.5e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CBS PF00571.23 CAM66844.1 - 0.053 13.3 0.1 0.56 10.0 0.0 2.6 2 0 0 2 2 2 0 CBS domain CorA PF01544.13 CAM66845.1 - 5.6e-26 91.2 5.7 5.2e-23 81.4 0.5 2.3 1 1 0 2 2 2 2 CorA-like Mg2+ transporter protein SHOCT PF09851.4 CAM66845.1 - 1.4e-05 24.3 0.1 2.4e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 Short C-terminal domain DUF2217 PF10265.4 CAM66845.1 - 5.6 5.6 13.8 2.9 6.5 7.4 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) MIF4G PF02854.14 CAM66846.1 - 2.6e-10 40.0 0.0 5.7e-10 38.9 0.0 1.5 1 1 0 1 1 1 1 MIF4G domain DUF4455 PF14643.1 CAM66846.1 - 0.0016 17.1 0.6 0.0016 17.1 0.4 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4455) Actin PF00022.14 CAM66847.1 - 1.6e-102 342.9 0.0 1.8e-102 342.7 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CAM66847.1 - 0.003 16.1 0.1 0.13 10.8 0.0 2.5 3 0 0 3 3 3 2 MreB/Mbl protein EF-hand_7 PF13499.1 CAM66848.1 - 0.093 12.8 0.0 0.47 10.6 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair RabGAP-TBC PF00566.13 CAM66851.1 - 0.0001 21.8 0.2 0.00022 20.7 0.2 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain 2OG-FeII_Oxy PF03171.15 CAM66852.1 - 9.2e-11 41.9 0.0 2.8e-10 40.3 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily dTDP_sugar_isom PF00908.12 CAM66852.1 - 0.065 12.5 0.0 0.18 11.1 0.0 1.6 2 0 0 2 2 2 0 dTDP-4-dehydrorhamnose 3,5-epimerase Actin PF00022.14 CAM66853.1 - 1.6e-74 250.7 0.0 2.4e-74 250.1 0.0 1.2 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CAM66853.1 - 9.8e-10 37.5 0.0 1.8e-09 36.6 0.0 1.4 1 1 0 1 1 1 1 MreB/Mbl protein RE_Eco29kI PF09517.5 CAM66853.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Eco29kI restriction endonuclease DUF1796 PF08795.5 CAM66854.1 - 4e-49 166.4 0.0 7e-49 165.6 0.0 1.4 1 0 0 1 1 1 1 Putative papain-like cysteine peptidase (DUF1796) Nop PF01798.13 CAM66855.1 - 1.5e-53 180.0 0.8 1.5e-53 180.0 0.5 1.8 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 CAM66855.1 - 5.1e-26 90.2 0.0 9.8e-26 89.3 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 CAM66855.1 - 4.3e-05 23.5 1.0 0.13 12.4 0.1 2.6 1 1 1 2 2 2 2 NOP5NT (NUC127) domain DUF3306 PF11748.3 CAM66855.1 - 0.26 11.9 1.6 1 10.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) TMEM164 PF14808.1 CAM66856.1 - 3.2e-09 36.3 4.7 4.7e-09 35.8 3.3 1.2 1 0 0 1 1 1 1 TMEM164 family Whib PF02467.11 CAM66857.1 - 0.014 15.6 1.0 0.27 11.5 0.1 2.5 2 0 0 2 2 2 0 Transcription factor WhiB Alkyl_sulf_dimr PF14863.1 CAM66857.1 - 0.049 13.8 0.1 0.083 13.1 0.1 1.3 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation zf-RING_2 PF13639.1 CAM66858.1 - 8e-13 47.9 8.6 1.8e-12 46.8 5.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CAM66858.1 - 6.6e-08 32.4 8.0 1.2e-07 31.6 5.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CAM66858.1 - 4.1e-07 30.0 5.4 1e-06 28.7 3.7 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CAM66858.1 - 1.8e-06 27.4 5.4 3.4e-06 26.6 3.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAM66858.1 - 0.00014 21.4 5.6 0.00027 20.6 3.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CAM66858.1 - 0.00015 21.3 6.1 0.00028 20.4 4.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CAM66858.1 - 0.00042 19.9 3.1 0.00089 18.9 2.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.3 CAM66858.1 - 0.013 15.4 7.3 0.29 11.1 5.1 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Apc11 PF12861.2 CAM66858.1 - 0.021 14.6 4.6 0.051 13.4 3.2 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF983 PF06170.7 CAM66858.1 - 5.3 7.2 0.0 5.3 7.2 0.0 3.7 4 1 0 4 4 4 0 Protein of unknown function (DUF983) tRNA-synt_1c PF00749.16 CAM66861.1 - 2e-100 335.5 0.0 2.6e-100 335.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 CAM66861.1 - 2.9e-40 137.7 0.0 4.8e-40 137.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain PCNA_N PF00705.13 CAM66862.1 - 1.3e-41 141.1 1.3 2e-41 140.4 0.6 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 CAM66862.1 - 5.3e-38 129.8 0.1 1.2e-19 70.4 0.1 2.3 2 0 0 2 2 2 2 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 CAM66862.1 - 9.5e-08 31.4 0.0 1.2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 CAM66862.1 - 7.6e-05 21.6 0.1 0.0015 17.3 0.1 2.2 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.7 CAM66862.1 - 0.0031 16.4 0.0 0.12 11.3 0.0 2.2 2 0 0 2 2 2 1 Hus1-like protein GHMP_kinases_N PF00288.21 CAM66863.1 - 2e-12 47.0 0.7 6.9e-12 45.2 0.5 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CAM66863.1 - 9.3e-07 28.9 0.2 2.8e-05 24.2 0.0 2.7 2 0 0 2 2 2 1 GHMP kinases C terminal Ribosomal_L7Ae PF01248.21 CAM66865.1 - 5.7e-25 86.6 0.1 6.7e-25 86.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.1 CAM66865.1 - 0.00052 19.7 0.0 0.00072 19.2 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.6 CAM66865.1 - 0.0012 18.7 0.2 0.0013 18.6 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PDEase_I PF00233.14 CAM66866.1 - 7.6e-60 202.6 0.1 2.2e-59 201.0 0.0 1.8 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.21 CAM66866.1 - 5.9e-41 140.1 0.2 1.1e-20 74.2 0.0 3.4 3 1 0 3 3 3 2 GAF domain GAF_3 PF13492.1 CAM66866.1 - 1.9e-20 73.2 0.1 1.5e-09 37.9 0.0 3.5 3 0 0 3 3 3 3 GAF domain GAF_2 PF13185.1 CAM66866.1 - 1.9e-18 67.3 0.0 9.3e-07 29.4 0.0 3.4 3 0 0 3 3 3 3 GAF domain PDEase_I PF00233.14 CAM66867.1 - 1.5e-60 204.8 0.3 3.9e-60 203.5 0.1 1.8 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.21 CAM66867.1 - 1e-41 142.5 0.0 1.1e-20 74.2 0.0 2.6 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.1 CAM66867.1 - 3.4e-19 69.2 0.1 1.1e-09 38.4 0.0 3.4 3 0 0 3 3 3 2 GAF domain GAF_2 PF13185.1 CAM66867.1 - 5.7e-17 62.5 0.1 4.1e-07 30.6 0.0 3.3 3 0 0 3 3 3 2 GAF domain HMG_box_2 PF09011.5 CAM66868.1 - 0.056 13.8 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 HMG-box domain Sld5 PF05916.6 CAM66870.1 - 0.086 13.1 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 GINS complex protein Presenilin PF01080.12 CAM66872.1 - 1.1e-49 169.3 31.1 1.1e-34 119.9 12.0 2.0 1 1 1 2 2 2 2 Presenilin Wyosine_form PF08608.7 CAM66873.1 - 1.9e-19 69.5 0.0 5e-19 68.1 0.0 1.8 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.16 CAM66873.1 - 4.7e-19 69.1 0.0 8.5e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Pkinase PF00069.20 CAM66875.1 - 8.8e-61 205.3 0.0 1.1e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM66875.1 - 1.1e-26 93.5 0.0 7.8e-26 90.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase FYVE PF01363.16 CAM66875.1 - 1.2e-15 57.1 5.6 2.5e-15 56.1 3.9 1.5 1 0 0 1 1 1 1 FYVE zinc finger APH PF01636.18 CAM66875.1 - 6.6e-05 22.7 0.1 0.00082 19.1 0.0 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family FYVE_2 PF02318.11 CAM66875.1 - 0.00034 20.5 4.2 0.00034 20.5 2.9 1.9 2 0 0 2 2 2 1 FYVE-type zinc finger Kinase-like PF14531.1 CAM66875.1 - 0.003 16.5 0.0 0.0044 16.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 CAM66875.1 - 0.027 14.0 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Siva PF05458.7 CAM66875.1 - 0.29 10.6 4.9 0.74 9.3 3.4 1.6 1 0 0 1 1 1 0 Cd27 binding protein (Siva) NOB1_Zn_bind PF08772.6 CAM66875.1 - 0.33 10.7 7.1 0.13 12.1 2.5 2.0 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-RING_5 PF14634.1 CAM66875.1 - 0.34 10.6 10.6 0.21 11.3 5.8 1.9 2 0 0 2 2 2 0 zinc-RING finger domain Cnd1 PF12717.2 CAM66876.1 - 6.2e-42 143.4 1.9 1.8e-35 122.3 0.1 4.4 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CAM66876.1 - 9.7e-07 28.9 1.9 0.18 12.0 0.2 5.2 2 2 2 4 4 4 3 HEAT repeats HEAT PF02985.17 CAM66876.1 - 2.5e-05 24.0 8.4 0.5 10.5 0.0 6.4 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 CAM66876.1 - 8.3e-05 22.9 0.1 3.6 8.2 0.0 4.9 3 0 0 3 3 3 1 HEAT-like repeat Cnd1_N PF12922.2 CAM66876.1 - 0.0035 16.9 0.0 0.019 14.6 0.0 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term SR-25 PF10500.4 CAM66877.1 - 0.047 13.1 6.8 0.079 12.4 4.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-C2H2_4 PF13894.1 CAM66877.1 - 2.7 8.5 5.8 4.1 7.9 1.5 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger ASF1_hist_chap PF04729.8 CAM66879.1 - 8.4e-32 109.9 0.0 9.8e-32 109.7 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone Ribosomal_L18e PF00828.14 CAM66880.1 - 0.028 14.8 0.0 0.05 13.9 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L18e/L15 AAA_17 PF13207.1 CAM66881.1 - 1.9e-11 44.8 0.0 3.9e-11 43.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain ADK PF00406.17 CAM66881.1 - 9.1e-11 41.8 0.4 0.00049 19.9 0.0 2.2 1 1 0 2 2 2 2 Adenylate kinase AAA_19 PF13245.1 CAM66881.1 - 1.2e-08 34.5 0.4 2.5e-08 33.5 0.3 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 CAM66881.1 - 8.1e-08 32.2 0.1 4.8e-07 29.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CAM66881.1 - 1.3e-06 28.4 1.4 7e-06 26.0 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CAM66881.1 - 2e-06 28.1 0.1 6.5e-06 26.4 0.1 1.8 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 CAM66881.1 - 8.1e-06 26.0 0.1 2.4e-05 24.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 CAM66881.1 - 1.4e-05 24.2 0.3 3.1e-05 23.1 0.1 1.5 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CAM66881.1 - 2.4e-05 24.4 0.1 5.6e-05 23.2 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain SRP54 PF00448.17 CAM66881.1 - 0.00016 21.1 0.1 0.00029 20.3 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 CAM66881.1 - 0.00024 20.5 0.1 0.00039 19.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 CAM66881.1 - 0.00025 20.8 0.1 0.00046 19.9 0.1 1.4 1 0 0 1 1 1 1 NTPase AAA PF00004.24 CAM66881.1 - 0.00033 20.8 0.2 0.0007 19.8 0.2 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CAM66881.1 - 0.00081 19.1 0.0 0.0024 17.5 0.0 1.8 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) NACHT PF05729.7 CAM66881.1 - 0.001 18.7 0.1 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Zeta_toxin PF06414.7 CAM66881.1 - 0.0011 18.0 0.0 0.0028 16.8 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_14 PF13173.1 CAM66881.1 - 0.0014 18.4 0.0 0.0038 17.1 0.0 1.7 2 0 0 2 2 1 1 AAA domain KTI12 PF08433.5 CAM66881.1 - 0.0024 17.1 0.0 0.0039 16.4 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_10 PF12846.2 CAM66881.1 - 0.0026 17.2 0.0 0.0047 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain AAA_24 PF13479.1 CAM66881.1 - 0.0035 16.9 0.2 0.0089 15.6 0.1 1.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 CAM66881.1 - 0.0046 16.4 0.0 0.0076 15.7 0.0 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Cytidylate_kin2 PF13189.1 CAM66881.1 - 0.0069 16.3 0.1 0.014 15.2 0.1 1.8 1 1 0 1 1 1 1 Cytidylate kinase-like family Mg_chelatase PF01078.16 CAM66881.1 - 0.0078 15.3 0.1 0.014 14.6 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI T2SE PF00437.15 CAM66881.1 - 0.0094 14.8 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Sigma54_activ_2 PF14532.1 CAM66881.1 - 0.014 15.4 0.1 0.029 14.4 0.0 1.7 2 1 0 2 2 1 0 Sigma-54 interaction domain AAA_29 PF13555.1 CAM66881.1 - 0.019 14.5 0.0 0.039 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 CAM66881.1 - 0.019 14.6 0.1 0.042 13.5 0.0 1.6 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 CAM66881.1 - 0.02 14.2 0.4 0.036 13.4 0.3 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.17 CAM66881.1 - 0.024 14.8 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.4 CAM66881.1 - 0.024 13.6 0.1 0.038 12.9 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.13 CAM66881.1 - 0.027 13.9 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family UPF0079 PF02367.12 CAM66881.1 - 0.032 13.8 0.1 0.25 10.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_3 PF07726.6 CAM66881.1 - 0.044 13.3 0.0 0.095 12.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CobU PF02283.11 CAM66881.1 - 0.047 13.0 0.1 0.084 12.2 0.1 1.4 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_30 PF13604.1 CAM66881.1 - 0.048 13.2 0.3 0.081 12.5 0.2 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CAM66881.1 - 0.063 13.5 0.1 0.087 13.1 0.1 1.5 1 1 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.13 CAM66881.1 - 0.071 12.6 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Thymidylate_kin PF02223.12 CAM66881.1 - 0.08 12.3 0.1 2.8 7.2 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase NB-ARC PF00931.17 CAM66881.1 - 0.086 11.6 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain KAP_NTPase PF07693.9 CAM66881.1 - 0.088 11.7 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain ATP_bind_1 PF03029.12 CAM66881.1 - 0.091 12.2 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein APS_kinase PF01583.15 CAM66881.1 - 0.091 12.4 0.2 0.25 11.0 0.0 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase PhoH PF02562.11 CAM66881.1 - 0.093 11.9 0.1 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.10 CAM66881.1 - 0.1 12.4 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_23 PF13476.1 CAM66881.1 - 0.1 12.9 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 CAM66881.1 - 0.11 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CAM66881.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase PRK PF00485.13 CAM66881.1 - 0.11 12.0 0.2 0.21 11.1 0.0 1.5 2 0 0 2 2 1 0 Phosphoribulokinase / Uridine kinase family Arch_ATPase PF01637.13 CAM66881.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase KaiC PF06745.8 CAM66881.1 - 0.13 11.3 0.1 0.24 10.4 0.1 1.5 1 1 0 1 1 1 0 KaiC CoaE PF01121.15 CAM66881.1 - 0.17 11.2 0.6 0.36 10.1 0.1 1.8 2 0 0 2 2 1 0 Dephospho-CoA kinase SKI PF01202.17 CAM66881.1 - 0.21 11.4 1.2 1.3 8.8 0.1 2.2 2 0 0 2 2 2 0 Shikimate kinase Methyltransf_26 PF13659.1 CAM66882.1 - 3.2e-05 23.9 0.1 6.1e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CAM66882.1 - 0.00014 21.1 0.4 0.0002 20.6 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 CAM66882.1 - 0.00077 18.8 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 CAM66882.1 - 0.003 18.1 0.0 0.006 17.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain AcetDehyd-dimer PF09290.6 CAM66882.1 - 0.089 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation CMAS PF02353.15 CAM66882.1 - 0.12 11.4 0.3 0.26 10.3 0.0 1.7 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase 2OG-FeII_Oxy_3 PF13640.1 CAM66883.1 - 5.1e-12 46.1 0.1 1e-11 45.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 CAM66883.1 - 1.4e-07 31.0 0.4 4e-07 29.5 0.3 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.8 CAM66883.1 - 7.8e-05 22.8 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy PF03171.15 CAM66883.1 - 0.026 14.8 0.1 0.082 13.2 0.1 1.8 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.8 CAM66883.1 - 0.064 12.0 0.0 0.14 10.9 0.0 1.5 1 1 0 1 1 1 0 Poxvirus C4/C10 protein TPR_6 PF13174.1 CAM66883.1 - 0.073 13.5 0.1 0.26 11.8 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat DEAD PF00270.24 CAM66884.2 - 7.7e-17 61.3 0.0 1.6e-14 53.7 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM66884.2 - 4e-15 55.4 0.0 1.2e-14 53.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAM66884.2 - 0.016 15.0 0.0 0.15 11.8 0.0 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CAM66884.2 - 0.038 14.1 0.0 12 6.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain DUF1491 PF07372.7 CAM66884.2 - 0.11 12.4 0.1 0.35 10.8 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1491) AAA PF00004.24 CAM66885.2 - 1.8e-45 154.4 0.0 3.9e-45 153.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CAM66885.2 - 6.5e-07 28.6 0.0 1.2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Vps4_C PF09336.5 CAM66885.2 - 0.00011 21.9 0.0 0.0003 20.6 0.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.9 CAM66885.2 - 0.00015 21.6 0.0 0.00034 20.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CAM66885.2 - 0.00031 20.7 1.5 0.0097 15.9 0.0 3.4 3 1 1 4 4 4 1 AAA ATPase domain AAA_5 PF07728.9 CAM66885.2 - 0.00038 20.2 0.0 0.0017 18.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CAM66885.2 - 0.00041 20.5 0.0 0.019 15.1 0.0 3.0 2 1 1 3 3 3 1 AAA domain AAA_17 PF13207.1 CAM66885.2 - 0.00056 20.7 0.0 0.0016 19.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CAM66885.2 - 0.00082 19.2 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CAM66885.2 - 0.0025 17.6 0.0 0.0099 15.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain Parvo_NS1 PF01057.12 CAM66885.2 - 0.0027 16.6 0.0 0.0047 15.8 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.7 CAM66885.2 - 0.0031 16.6 0.0 0.0059 15.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin IstB_IS21 PF01695.12 CAM66885.2 - 0.0036 16.7 0.0 0.0083 15.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 CAM66885.2 - 0.0039 17.3 0.0 0.0087 16.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 CAM66885.2 - 0.015 14.0 0.0 0.026 13.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus ABC_tran PF00005.22 CAM66885.2 - 0.015 15.5 0.0 0.036 14.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.16 CAM66885.2 - 0.016 14.4 0.1 0.029 13.5 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 CAM66885.2 - 0.022 14.7 0.0 0.14 12.1 0.0 2.4 3 0 0 3 3 2 0 AAA domain PhoH PF02562.11 CAM66885.2 - 0.033 13.4 0.0 0.069 12.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.1 CAM66885.2 - 0.046 13.1 0.1 0.19 11.1 0.0 2.0 1 1 1 2 2 2 0 AAA domain SKI PF01202.17 CAM66885.2 - 0.048 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase KaiC PF06745.8 CAM66885.2 - 0.05 12.7 0.0 0.094 11.8 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_24 PF13479.1 CAM66885.2 - 0.072 12.6 0.4 0.17 11.4 0.1 1.7 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 CAM66885.2 - 0.12 11.2 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.1 CAM66885.2 - 0.23 11.7 0.0 0.42 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain INT_SG_DDX_CT_C PF15300.1 CAM66886.1 - 0.054 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus Kelch_4 PF13418.1 CAM66887.1 - 5.6e-34 115.6 0.4 1.7e-08 34.0 0.0 6.9 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 CAM66887.1 - 3e-32 110.0 2.1 6.5e-08 32.5 0.0 7.1 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.1 CAM66887.1 - 2.6e-28 97.4 1.2 0.00048 20.0 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 CAM66887.1 - 4.5e-23 80.4 4.1 9.1e-05 22.4 0.0 6.3 5 1 1 6 6 6 5 Kelch motif Kelch_1 PF01344.20 CAM66887.1 - 1.4e-20 72.5 0.0 9.8e-06 25.0 0.0 5.4 5 0 0 5 5 5 4 Kelch motif DUF4110 PF13422.1 CAM66887.1 - 2.2e-20 72.2 13.0 2.2e-20 72.2 9.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_2 PF07646.10 CAM66887.1 - 1.3e-15 56.4 2.4 0.0032 17.1 0.0 6.4 6 0 0 6 6 6 4 Kelch motif MORN PF02493.15 CAM66889.1 - 7.7e-13 47.3 7.9 3e-08 32.8 0.6 4.3 4 0 0 4 4 4 2 MORN repeat APH PF01636.18 CAM66890.1 - 8.5e-13 48.5 0.0 2.1e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family eIF-1a PF01176.14 CAM66893.1 - 3.5e-18 64.7 0.4 4.9e-18 64.2 0.3 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 YL1 PF05764.8 CAM66893.1 - 0.21 11.1 3.6 0.37 10.3 2.5 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Ribosomal_L17 PF01196.14 CAM66895.1 - 6.4e-15 55.5 0.1 9.3e-15 54.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L17 CD52 PF15116.1 CAM66897.1 - 0.064 13.0 0.4 0.15 11.8 0.3 1.6 1 0 0 1 1 1 0 CAMPATH-1 antigen Las1 PF04031.8 CAM66898.1 - 8.3e-41 139.2 0.0 1.2e-40 138.6 0.0 1.2 1 0 0 1 1 1 1 Las1-like Mito_carr PF00153.22 CAM66899.1 - 3.1e-67 222.3 0.3 1.4e-22 79.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.22 CAM66900.1 - 2.6e-56 187.3 4.0 6.8e-20 70.5 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DSPc PF00782.15 CAM66902.1 - 2.5e-08 33.5 0.0 3e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CAM66902.1 - 1.1e-05 24.9 0.0 1.3e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Radical_SAM PF04055.16 CAM66903.1 - 8e-14 52.1 0.0 2.7e-13 50.4 0.0 1.9 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 CAM66903.1 - 3.6e-08 33.3 0.1 3.6e-07 30.1 0.1 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CAM66903.1 - 0.077 13.1 0.2 0.25 11.4 0.1 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DSPc PF00782.15 CAM66904.1 - 2.8e-08 33.3 0.0 3.3e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CAM66904.1 - 7.5e-06 25.4 0.0 2.1e-05 24.0 0.0 1.5 1 1 1 2 2 2 1 Protein-tyrosine phosphatase Abhydrolase_5 PF12695.2 CAM66905.1 - 1.3e-25 89.8 0.0 1.9e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CAM66905.1 - 4.3e-17 62.7 0.0 8.1e-17 61.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ank_5 PF13857.1 CAM66905.1 - 3e-10 39.9 0.1 6.2e-09 35.8 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 CAM66905.1 - 3.9e-08 33.5 0.0 4.5e-07 30.1 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CAM66905.1 - 2e-07 31.2 0.6 0.00056 20.3 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Peptidase_S9 PF00326.16 CAM66905.1 - 2.1e-06 27.0 0.1 0.033 13.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Ank_3 PF13606.1 CAM66905.1 - 4.6e-06 26.3 0.1 4.6e-05 23.2 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat AXE1 PF05448.7 CAM66905.1 - 3.9e-05 22.3 0.9 0.0047 15.4 0.6 2.2 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Ank PF00023.25 CAM66905.1 - 0.00013 21.5 0.0 0.00049 19.7 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Hydrolase_4 PF12146.3 CAM66905.1 - 0.00062 19.5 0.6 0.0022 17.7 0.1 2.1 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 CAM66905.1 - 0.001 18.7 0.4 0.47 9.9 0.2 2.7 2 1 1 3 3 3 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 CAM66905.1 - 0.018 14.5 0.0 0.091 12.1 0.0 1.9 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydro_lipase PF04083.11 CAM66905.1 - 0.085 12.2 0.0 15 5.0 0.0 2.4 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region DUF2424 PF10340.4 CAM66905.1 - 0.18 10.4 0.1 3.1 6.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) PPR_3 PF13812.1 CAM66906.1 - 0.025 14.8 2.0 55 4.4 0.2 4.4 3 0 0 3 3 3 0 Pentatricopeptide repeat domain Ins145_P3_rec PF08709.6 CAM66907.1 - 1.5e-42 145.0 0.0 1.9e-41 141.4 0.0 2.7 2 1 0 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor RIH_assoc PF08454.6 CAM66907.1 - 3.9e-24 84.4 0.6 1.6e-23 82.4 0.4 2.2 2 0 0 2 2 2 1 RyR and IP3R Homology associated MIR PF02815.14 CAM66907.1 - 0.002 17.6 0.1 0.58 9.6 0.0 2.7 2 1 0 2 2 2 2 MIR domain Rhabdo_M1 PF03342.8 CAM66907.1 - 0.093 11.8 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) Ion_trans PF00520.26 CAM66907.1 - 0.29 10.3 11.2 0.63 9.2 7.8 1.5 1 0 0 1 1 1 0 Ion transport protein GRASP55_65 PF04495.9 CAM66908.1 - 0.0023 17.9 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.19 CAM66908.1 - 0.05 13.7 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CAM66908.1 - 0.077 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Pkinase PF00069.20 CAM66909.1 - 2.7e-68 229.9 0.0 3.5e-68 229.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM66909.1 - 3.8e-49 167.0 0.0 5e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM66909.1 - 0.00093 18.2 0.0 0.0029 16.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like CT47 PF15623.1 CAM66909.1 - 0.018 14.7 3.7 0.033 13.9 2.6 1.4 1 0 0 1 1 1 0 Cancer/testis gene family 47 Met_10 PF02475.11 CAM66910.1 - 1.2e-47 162.1 0.0 5.7e-35 120.7 0.0 2.2 2 0 0 2 2 2 2 Met-10+ like-protein Methyltransf_26 PF13659.1 CAM66910.1 - 0.0033 17.4 3.0 0.0055 16.7 0.1 2.8 2 2 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 CAM66910.1 - 0.0061 15.7 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TRM PF02005.11 CAM66910.1 - 0.06 12.2 0.0 0.098 11.5 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Glyco_transf_64 PF09258.5 CAM66910.1 - 0.2 10.8 0.0 0.33 10.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 64 domain FHA PF00498.21 CAM66911.1 - 2.4e-14 53.1 0.0 4.6e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 FHA domain EBP PF05241.7 CAM66913.1 - 1.7e-30 105.5 1.9 2.1e-30 105.2 1.3 1.1 1 0 0 1 1 1 1 Emopamil binding protein 2OG-FeII_Oxy_2 PF13532.1 CAM66914.1 - 2.6e-53 180.7 0.1 3.4e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 4HBT PF03061.17 CAM66915.2 - 0.056 13.5 1.5 0.18 11.9 0.6 2.2 2 0 0 2 2 2 0 Thioesterase superfamily Beta_helix PF13229.1 CAM66916.1 - 0.0086 15.8 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 Right handed beta helix region NosD PF05048.8 CAM66916.1 - 0.02 14.0 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) TTL PF03133.10 CAM66917.1 - 1.2e-77 260.7 0.0 1.4e-76 257.2 0.0 2.2 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATP-grasp_4 PF13535.1 CAM66917.1 - 0.0077 15.9 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_YheCD PF14398.1 CAM66917.1 - 0.0081 14.9 0.0 0.47 9.2 0.0 2.3 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.1 CAM66917.1 - 0.025 13.6 0.0 4.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.9 CAM66917.1 - 0.11 12.4 0.0 2.9 7.7 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain RimK PF08443.6 CAM66917.1 - 0.12 11.8 0.0 3.8 6.9 0.0 2.2 2 0 0 2 2 2 0 RimK-like ATP-grasp domain XRN_N PF03159.13 CAM66918.1 - 3.6e-16 59.2 0.5 7e-12 45.2 0.1 2.9 2 1 1 3 3 3 2 XRN 5'-3' exonuclease N-terminus Macoilin PF09726.4 CAM66920.1 - 0.18 10.0 3.3 0.26 9.5 2.3 1.3 1 0 0 1 1 1 0 Transmembrane protein Pyridoxal_deC PF00282.14 CAM66921.1 - 1.6e-21 76.2 0.1 2.7e-19 68.8 0.0 2.5 2 1 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Fucokinase PF07959.7 CAM66923.2 - 5.1e-29 101.0 0.0 5.3e-20 71.3 0.0 3.1 2 1 0 2 2 2 2 L-fucokinase GHMP_kinases_N PF00288.21 CAM66923.2 - 2.3e-06 27.5 0.0 1e-05 25.5 0.0 2.2 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CAM66923.2 - 0.0029 17.7 0.0 0.011 15.9 0.0 2.1 1 0 0 1 1 1 1 GHMP kinases C terminal Ribosomal_L21e PF01157.13 CAM66925.1 - 3.1e-34 116.7 2.2 4.4e-34 116.2 1.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e DUF2705 PF10920.3 CAM66926.1 - 0.053 12.7 2.0 3.1 6.9 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2705) Cation_efflux PF01545.16 CAM66926.1 - 0.1 11.6 6.9 0.056 12.5 2.0 2.1 1 1 1 2 2 2 0 Cation efflux family SUR7 PF06687.7 CAM66926.1 - 0.16 11.4 15.2 0.73 9.3 7.3 2.2 2 0 0 2 2 2 0 SUR7/PalI family DUF3139 PF11337.3 CAM66926.1 - 0.52 10.6 2.9 28 5.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) VIT1 PF01988.14 CAM66926.1 - 2.1 7.7 8.1 0.079 12.4 0.7 2.1 1 1 1 2 2 2 0 VIT family Tetraspannin PF00335.15 CAM66926.1 - 2.1 7.5 20.8 0.02 14.1 7.1 2.1 1 1 1 2 2 2 0 Tetraspanin family Fucokinase PF07959.7 CAM66927.1 - 5.1e-29 101.0 0.0 5.3e-20 71.3 0.0 3.1 2 1 0 2 2 2 2 L-fucokinase GHMP_kinases_N PF00288.21 CAM66927.1 - 2.4e-06 27.4 0.0 1e-05 25.5 0.0 2.1 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CAM66927.1 - 0.0029 17.7 0.0 0.011 15.9 0.0 2.1 1 0 0 1 1 1 1 GHMP kinases C terminal Amastin PF07344.6 CAM66929.1 - 2.3e-05 24.0 14.9 3e-05 23.6 10.1 1.4 1 1 0 1 1 1 1 Amastin surface glycoprotein EphA2_TM PF14575.1 CAM66929.1 - 1.5 9.2 8.4 3 8.3 0.0 3.8 3 1 1 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain CbiQ PF02361.11 CAM66929.1 - 1.7 8.1 15.1 0.39 10.2 6.5 2.0 2 0 0 2 2 2 0 Cobalt transport protein RLL PF10036.4 CAM66931.1 - 0.022 14.2 0.2 0.033 13.6 0.1 1.3 1 0 0 1 1 1 0 Putative carnitine deficiency-associated protein Ependymin PF00811.13 CAM66931.1 - 0.1 12.3 0.7 0.19 11.4 0.2 1.6 2 0 0 2 2 2 0 Ependymin OTCace_N PF02729.16 CAM66933.1 - 3.5e-42 143.4 0.5 5.1e-42 142.8 0.3 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 CAM66933.1 - 9.7e-35 119.7 0.1 7.3e-33 113.6 0.0 2.1 2 0 0 2 2 2 2 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OMPdecase PF00215.19 CAM66934.1 - 4.3e-39 134.2 0.0 6.5e-39 133.6 0.0 1.3 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.22 CAM66934.1 - 2.8e-18 65.8 2.1 1.4e-17 63.5 1.5 2.2 1 1 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.1 CAM66934.1 - 0.00018 20.8 0.0 0.00034 19.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase UPRTase PF14681.1 CAM66934.1 - 0.00094 18.4 0.0 0.0018 17.5 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase KA1 PF02149.14 CAM66934.1 - 0.08 12.4 0.0 0.65 9.4 0.0 2.4 2 0 0 2 2 2 0 Kinase associated domain 1 AAA_17 PF13207.1 CAM66935.1 - 9.7e-07 29.6 0.0 2.9e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CAM66935.1 - 0.001 19.4 0.1 0.0029 17.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain PRK PF00485.13 CAM66935.1 - 0.0073 15.8 0.0 0.019 14.5 0.0 1.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 CAM66935.1 - 0.014 15.2 0.0 0.047 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain CPT PF07931.7 CAM66935.1 - 0.082 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Amidohydro_4 PF13147.1 CAM66939.1 - 1.7e-21 77.4 9.4 1.2e-20 74.7 6.5 2.2 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 CAM66939.1 - 7.5e-06 25.8 0.0 1.4e-05 24.9 0.0 1.6 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 CAM66939.1 - 0.0017 18.1 0.0 0.0048 16.6 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.9 CAM66939.1 - 0.0043 16.6 0.2 0.29 10.6 0.2 2.3 2 0 0 2 2 2 1 Amidohydrolase DHOase PF12890.2 CAM66939.1 - 0.011 15.4 0.1 0.09 12.4 0.0 2.0 1 1 0 1 1 1 0 Dihydro-orotase-like TatD_DNase PF01026.16 CAM66939.1 - 0.022 13.9 1.7 0.072 12.2 1.0 2.0 2 1 0 2 2 2 0 TatD related DNase CPSase_L_D2 PF02786.12 CAM66940.1 - 2.5e-102 340.6 0.4 2.8e-77 258.7 0.1 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 CAM66940.1 - 1.5e-44 150.7 0.0 3.8e-44 149.3 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 CAM66940.1 - 5.4e-43 146.6 0.0 1.5e-42 145.2 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_chain PF00289.17 CAM66940.1 - 5.3e-36 123.0 0.0 7.5e-20 71.0 0.0 2.8 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 CAM66940.1 - 5.6e-35 120.7 1.2 1.9e-21 76.6 0.0 3.1 3 0 0 3 3 3 2 ATP-grasp domain CPSase_L_D3 PF02787.14 CAM66940.1 - 7.9e-35 119.3 0.0 1.6e-34 118.2 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.17 CAM66940.1 - 1.7e-21 76.3 0.4 3.1e-12 46.1 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 CAM66940.1 - 2.4e-21 75.8 0.0 1.2e-15 57.1 0.0 3.4 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon Arginosuc_synth PF00764.14 CAM66940.1 - 4.4e-14 52.3 0.1 3.2e-13 49.5 0.0 2.3 3 0 0 3 3 3 1 Arginosuccinate synthase Dala_Dala_lig_C PF07478.8 CAM66940.1 - 2.5e-12 46.6 0.4 7.1e-06 25.5 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.17 CAM66940.1 - 3.2e-12 46.2 0.0 1.4e-11 44.1 0.0 2.3 1 0 0 1 1 1 1 MGS-like domain Peptidase_C26 PF07722.8 CAM66940.1 - 4.1e-07 29.6 0.2 1.1e-05 24.9 0.1 2.4 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 CAM66940.1 - 7.6e-06 25.8 0.3 0.00067 19.5 0.0 2.7 2 1 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 CAM66940.1 - 1.9e-05 24.3 0.4 0.15 11.6 0.0 3.2 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain TrkA_N PF02254.13 CAM66940.1 - 0.013 15.4 0.0 0.077 13.0 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain GSH-S_ATP PF02955.11 CAM66940.1 - 0.025 13.7 0.0 0.079 12.1 0.0 1.8 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain DJ-1_PfpI PF01965.19 CAM66940.1 - 0.042 13.2 0.0 0.099 12.1 0.0 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family Histone PF00125.19 CAM66941.1 - 1.7e-27 95.3 0.6 1.7e-27 95.3 0.4 1.8 2 1 1 3 3 3 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CAM66941.1 - 5.9e-06 26.3 0.0 1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CAM66941.1 - 9.8e-06 25.5 0.2 9.8e-06 25.5 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CAM66941.1 - 0.00041 20.0 0.1 0.00063 19.4 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TMA7 PF09072.5 CAM66941.1 - 0.74 10.3 3.7 1.2 9.6 2.5 1.4 1 0 0 1 1 1 0 Translation machinery associated TMA7 Histone PF00125.19 CAM66942.1 - 1.7e-27 95.3 0.6 1.7e-27 95.3 0.4 1.8 2 1 1 3 3 3 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CAM66942.1 - 5.9e-06 26.3 0.0 1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CAM66942.1 - 9.8e-06 25.5 0.2 9.8e-06 25.5 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CAM66942.1 - 0.00041 20.0 0.1 0.00063 19.4 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TMA7 PF09072.5 CAM66942.1 - 0.74 10.3 3.7 1.2 9.6 2.5 1.4 1 0 0 1 1 1 0 Translation machinery associated TMA7 RRM_1 PF00076.17 CAM66945.1 - 1.3e-13 50.4 0.0 2.2e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM66945.1 - 4.5e-09 36.1 0.0 8.4e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM66945.1 - 2e-08 33.9 0.1 3.7e-08 33.0 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.16 CAM66945.1 - 2.9e-07 30.8 0.0 0.025 14.8 0.0 2.3 2 0 0 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-rbx1 PF12678.2 CAM66946.1 - 2.5e-18 65.9 6.3 3.1e-18 65.6 4.4 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CAM66946.1 - 4.2e-14 52.1 7.0 5.3e-14 51.8 4.9 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 CAM66946.1 - 8.9e-10 38.2 16.6 1.6e-08 34.2 11.6 2.1 1 1 1 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 CAM66946.1 - 5.9e-07 29.1 12.9 3.7e-06 26.5 6.0 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CAM66946.1 - 4e-06 26.7 11.9 0.00038 20.4 8.3 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CAM66946.1 - 1e-05 25.1 13.3 0.00033 20.2 5.6 2.6 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 CAM66946.1 - 2.9e-05 23.7 4.5 2.9e-05 23.7 3.1 1.9 1 1 1 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4 PF00097.20 CAM66946.1 - 0.00044 19.8 12.4 0.0023 17.5 8.6 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CAM66946.1 - 0.0014 18.2 10.5 0.0025 17.4 5.2 2.5 1 1 1 2 2 2 1 RING-type zinc-finger FANCL_C PF11793.3 CAM66946.1 - 0.008 16.1 13.5 0.025 14.5 2.5 3.1 1 1 1 3 3 3 1 FANCL C-terminal domain zf-RING_4 PF14570.1 CAM66946.1 - 0.017 14.6 8.8 0.49 10.0 4.1 2.5 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Rtf2 PF04641.7 CAM66946.1 - 0.026 13.7 2.4 0.056 12.6 1.7 1.6 1 1 1 2 2 2 0 Rtf2 RING-finger zf-Di19 PF05605.7 CAM66946.1 - 0.12 12.4 8.5 9.4 6.4 5.9 2.3 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_4 PF15227.1 CAM66946.1 - 0.14 12.0 13.5 11 6.0 1.4 3.5 1 1 2 3 3 3 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 CAM66946.1 - 0.34 10.4 6.9 1.2 8.6 4.8 1.9 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit C1_1 PF00130.17 CAM66946.1 - 0.43 10.3 10.2 0.41 10.4 5.7 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1272 PF06906.6 CAM66946.1 - 1.7 8.5 10.3 2.2 8.2 3.9 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) TerY-C PF15616.1 CAM66946.1 - 1.7 8.5 10.0 12 5.8 0.4 2.1 1 1 1 2 2 2 0 TerY-C metal binding domain Prok-RING_4 PF14447.1 CAM66946.1 - 2.4 7.7 12.8 0.44 10.1 3.9 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 eIF2A PF08662.6 CAM66950.1 - 1.4e-37 129.2 0.0 1.8e-33 115.9 0.0 3.2 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 CAM66950.1 - 1.1 9.2 3.7 1e+02 3.0 0.0 4.1 5 0 0 5 5 5 0 WD domain, G-beta repeat LysM PF01476.15 CAM66951.1 - 1.3e-07 31.3 0.0 0.00035 20.4 0.0 2.6 3 0 0 3 3 3 2 LysM domain LRR_6 PF13516.1 CAM66953.1 - 3.8e-10 38.7 15.3 0.027 14.5 0.2 6.6 6 0 0 6 6 6 4 Leucine Rich repeat LRR_4 PF12799.2 CAM66953.1 - 2.6e-06 26.8 10.9 0.0038 16.8 0.4 5.4 5 1 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CAM66953.1 - 5.8e-06 25.6 12.0 4.4 7.7 0.0 5.9 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_8 PF13855.1 CAM66953.1 - 0.00023 20.8 8.2 0.037 13.7 0.2 4.4 4 0 0 4 4 4 2 Leucine rich repeat LRR_7 PF13504.1 CAM66953.1 - 0.071 13.3 14.9 25 5.6 0.1 6.1 5 0 0 5 5 5 0 Leucine rich repeat UCH PF00443.24 CAM66954.1 - 7e-41 140.1 0.0 1.2e-40 139.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CAM66954.1 - 9.7e-21 74.4 0.0 5.9e-20 71.8 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-RanBP PF00641.13 CAM66954.1 - 0.0056 15.7 0.9 0.0056 15.7 0.6 2.8 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others Transaldolase PF00923.14 CAM66957.1 - 2.4e-97 325.5 0.1 2.7e-97 325.3 0.0 1.0 1 0 0 1 1 1 1 Transaldolase SH3BGR PF04908.10 CAM66958.1 - 0.00045 20.1 0.0 0.00099 19.0 0.0 1.5 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Chorein_N PF12624.2 CAM66959.1 - 7.1e-17 61.0 0.3 2.5e-10 39.9 0.2 2.7 2 0 0 2 2 2 2 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF1162 PF06650.7 CAM66959.1 - 2.8e-07 30.0 0.2 0.23 10.6 0.0 4.1 3 1 0 3 3 3 3 Protein of unknown function (DUF1162) Meiotic_rec114 PF03525.9 CAM66959.1 - 0.16 10.3 0.1 0.42 9.0 0.1 1.6 1 0 0 1 1 1 0 Meiotic recombination protein rec114 Glyco_hydro_18 PF00704.23 CAM66960.1 - 2.1e-58 198.3 0.0 2.7e-58 198.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Mem_trans PF03547.13 CAM66961.1 - 8.7e-14 50.6 21.4 3.6e-12 45.2 0.0 3.2 3 0 0 3 3 3 2 Membrane transport protein Methyltransf_18 PF12847.2 CAM66962.1 - 0.027 15.0 0.0 0.08 13.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain EF-hand_1 PF00036.27 CAM66963.1 - 0.0044 16.2 0.0 0.0093 15.2 0.0 1.5 1 0 0 1 1 1 1 EF hand Fe-S_biosyn PF01521.15 CAM66964.2 - 8.5e-08 32.1 0.0 3.8e-07 30.0 0.0 2.0 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis JAB PF01398.16 CAM66966.1 - 2.7e-19 69.0 0.0 4.4e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 CAM66966.1 - 0.0012 18.3 0.0 0.003 17.0 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Pkinase PF00069.20 CAM66968.1 - 8e-34 116.9 0.0 1.4e-33 116.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM66968.1 - 1.8e-24 86.2 0.0 3.1e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase zf-H2C2_5 PF13909.1 CAM66968.1 - 0.053 13.7 2.2 0.14 12.4 1.5 1.7 1 0 0 1 1 1 0 C2H2-type zinc-finger domain Nop52 PF05997.7 CAM66970.1 - 5.9e-44 150.0 2.7 7.7e-37 126.8 0.0 3.9 4 0 0 4 4 4 3 Nucleolar protein,Nop52 Red1 PF07964.6 CAM66970.1 - 0.39 8.8 3.2 0.62 8.1 2.2 1.2 1 0 0 1 1 1 0 Rec10 / Red1 EF-hand_1 PF00036.27 CAM66973.1 - 8.4e-11 40.3 2.5 0.0001 21.3 0.0 3.6 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.1 CAM66973.1 - 8.4e-09 34.5 0.1 0.0017 18.0 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 CAM66973.1 - 2.1e-07 30.9 0.1 6.5e-07 29.3 0.0 2.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 CAM66973.1 - 3.3e-05 23.3 2.0 0.0044 16.6 0.0 3.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 CAM66973.1 - 0.0019 17.4 0.3 0.029 13.6 0.0 2.8 2 1 0 2 2 2 1 EF hand EF-hand_1 PF00036.27 CAM66974.1 - 2e-10 39.1 1.7 0.0002 20.4 0.0 3.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 CAM66974.1 - 5.7e-10 38.2 1.5 0.005 16.6 0.0 4.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 CAM66974.1 - 6.1e-08 32.6 0.1 2.1e-06 27.7 0.0 2.8 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 CAM66974.1 - 7.3e-05 22.3 1.2 0.0091 15.5 0.0 3.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 CAM66974.1 - 0.0052 16.0 0.8 0.053 12.8 0.0 3.0 4 0 0 4 4 4 1 EF hand Snf7 PF03357.16 CAM66975.1 - 1.7e-24 86.1 13.4 2.1e-24 85.8 9.3 1.2 1 0 0 1 1 1 1 Snf7 DUF3801 PF12687.2 CAM66975.1 - 0.00022 20.8 5.3 0.00024 20.7 3.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3801) Dynein_light PF01221.13 CAM66976.1 - 6.1e-27 93.4 0.6 7.1e-27 93.2 0.4 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 YsaB PF13983.1 CAM66976.1 - 0.057 13.5 0.0 0.083 13.0 0.0 1.3 1 0 0 1 1 1 0 YsaB-like lipoprotein YtxH PF12732.2 CAM66976.1 - 0.079 13.3 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 YtxH-like protein Integrase_DNA PF02920.10 CAM66976.1 - 0.093 12.1 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 DNA binding domain of tn916 integrase Glycos_transf_1 PF00534.15 CAM66977.1 - 1.7e-29 102.4 0.0 2.7e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CAM66977.1 - 2.8e-14 53.3 0.0 5.6e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CAM66977.1 - 6.9e-05 23.0 0.0 0.00015 21.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Methyltransf_11 PF08241.7 CAM66978.1 - 3.1e-15 56.4 0.0 1.6e-13 50.9 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAM66978.1 - 6.2e-13 48.7 0.0 8.3e-12 45.1 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 CAM66978.1 - 6e-12 45.1 0.0 1.1e-10 41.0 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 CAM66978.1 - 9.5e-07 28.5 0.0 0.00012 21.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAM66978.1 - 3.9e-06 27.2 0.0 0.00093 19.6 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAM66978.1 - 0.0055 17.0 0.0 0.067 13.5 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAM66978.1 - 0.033 14.7 2.2 0.11 13.0 0.1 2.7 2 1 1 3 3 3 0 Methyltransferase domain Reo_sigmaC PF04582.7 CAM66980.1 - 0.052 12.7 33.2 0.22 10.6 0.3 6.0 2 2 2 6 6 6 0 Reovirus sigma C capsid protein Pkinase PF00069.20 CAM66981.1 - 4.8e-59 199.6 0.0 8.2e-58 195.5 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM66981.1 - 2.2e-28 99.0 0.0 3.1e-19 69.0 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 CAM66981.1 - 0.097 11.6 0.0 3 6.7 0.0 2.2 2 0 0 2 2 2 0 Kinase-like DUF3184 PF11380.3 CAM66982.2 - 0 1141.4 32.4 5.6e-172 573.2 2.6 3.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3184) DUF3184 PF11380.3 CAM66983.2 - 1.8e-272 905.4 26.7 2.1e-153 511.8 8.0 3.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3184) DUF3184 PF11380.3 CAM66985.2 - 0 1101.0 30.4 1.9e-171 571.4 2.4 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF3184) DUF3184 PF11380.3 CAM66987.2 - 0 1304.3 5.0 0 1304.0 3.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3184) BCL_N PF04714.8 CAM66987.2 - 0.14 11.7 1.3 0.33 10.5 0.9 1.6 1 0 0 1 1 1 0 BCL7, N-terminal conserver region DUF3184 PF11380.3 CAM66988.2 - 0 1157.2 3.3 0 1157.0 2.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3184) Ufm1 PF03671.9 CAM66989.1 - 2.1e-27 94.6 0.1 2.7e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein DUF3184 PF11380.3 CAM66992.2 - 0 1100.9 30.9 2.3e-171 571.2 2.6 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3184) DUF1275 PF06912.6 CAM66992.2 - 0.12 11.5 0.1 0.21 10.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) Polyketide_cyc PF03364.15 CAM66995.1 - 2.3e-12 47.0 0.8 1.7e-11 44.2 0.5 2.1 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Antimicrobial_8 PF08103.6 CAM66995.1 - 0.061 13.2 1.0 0.67 9.9 0.0 2.5 2 0 0 2 2 2 0 Uperin family DUF4551 PF15087.1 CAM66995.1 - 2.5 6.3 3.7 3.5 5.8 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) tRNA_bind PF01588.15 CAM66997.2 - 1.7e-22 79.0 0.0 3.2e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain WW PF00397.21 CAM66998.1 - 1.7e-43 146.0 39.8 3.4e-13 49.1 1.0 6.0 6 0 0 6 6 6 4 WW domain Mcp5_PH PF12814.2 CAM66998.1 - 0.24 11.3 2.5 10 6.0 0.1 3.4 4 0 0 4 4 4 0 Meiotic cell cortex C-terminal pleckstrin homology Ribosomal_L39 PF00832.15 CAM67001.1 - 2.3e-19 68.5 14.3 2.6e-19 68.3 9.9 1.0 1 0 0 1 1 1 1 Ribosomal L39 protein Methyltransf_FA PF12248.3 CAM67001.1 - 0.081 12.9 0.0 0.089 12.8 0.0 1.1 1 0 0 1 1 1 0 Farnesoic acid 0-methyl transferase Adap_comp_sub PF00928.16 CAM67002.1 - 6.3e-13 48.4 0.0 9.8e-13 47.7 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CAM67002.1 - 0.00011 21.9 0.1 0.00019 21.1 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF221 PF02714.10 CAM67003.1 - 2.1e-30 105.7 8.5 3.4e-30 105.0 5.9 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 Methyltransf_9 PF08003.6 CAM67003.1 - 0.35 9.5 0.1 0.58 8.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Pro_isomerase PF00160.16 CAM67004.1 - 1.4e-32 113.0 0.0 2e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD dsrm PF00035.20 CAM67005.1 - 8.6e-05 23.0 0.2 0.86 10.2 0.1 4.3 4 0 0 4 4 4 1 Double-stranded RNA binding motif Cullin PF00888.17 CAM67006.1 - 6.6e-32 110.8 0.0 2.3e-18 66.1 0.0 4.3 5 0 0 5 5 5 4 Cullin family Cullin_Nedd8 PF10557.4 CAM67006.1 - 2.5e-18 65.6 0.0 4.4e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Cullin protein neddylation domain Ecm29 PF13001.2 CAM67008.2 - 0.25 9.7 0.7 8.2 4.7 0.0 2.4 3 0 0 3 3 3 0 Proteasome stabiliser LSM PF01423.17 CAM67009.1 - 6.2e-05 22.4 0.0 0.00014 21.3 0.0 1.7 1 1 0 1 1 1 1 LSM domain CIA30 PF08547.7 CAM67012.1 - 0.086 12.6 0.1 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) DAGK_acc PF00609.14 CAM67013.1 - 5.5e-21 75.3 0.0 9.9e-20 71.2 0.0 2.3 1 1 1 2 2 2 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 CAM67013.1 - 4.8e-07 29.2 0.0 2.3e-06 27.0 0.0 2.3 2 1 0 2 2 2 1 Diacylglycerol kinase catalytic domain Cytochrom_C PF00034.16 CAM67015.2 - 8.2e-09 36.1 0.0 1.5e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 CAM67015.2 - 6.6e-05 22.9 1.1 0.00055 20.0 0.8 2.2 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 CAM67016.1 - 1.1e-09 39.0 0.0 1.5e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 CAM67016.1 - 7.3e-06 26.0 0.9 6.9e-05 22.9 0.6 2.1 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III LRR_4 PF12799.2 CAM67017.2 - 7.6e-28 95.6 21.6 0.0016 17.9 0.2 12.0 8 4 4 13 13 13 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM67017.2 - 1.1e-12 47.5 28.6 0.0021 17.7 2.3 8.9 7 2 2 9 9 9 6 Leucine rich repeat LRR_6 PF13516.1 CAM67017.2 - 2.7e-08 33.0 25.5 22 5.5 0.0 14.3 15 2 2 17 17 17 1 Leucine Rich repeat LRR_9 PF14580.1 CAM67017.2 - 0.013 15.0 16.4 0.68 9.4 0.2 5.0 3 2 1 5 5 5 0 Leucine-rich repeat LRR_1 PF00560.28 CAM67017.2 - 1.2 9.3 25.5 49 4.5 0.0 10.9 11 0 0 11 11 11 0 Leucine Rich Repeat RNA_pol_Rpb1_5 PF04998.12 CAM67019.1 - 2.3e-61 207.4 0.0 4.7e-61 206.4 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 CAM67019.1 - 6.1e-46 156.4 0.0 1.1e-45 155.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 CAM67019.1 - 2.6e-30 105.2 0.0 5.9e-30 104.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 CAM67019.1 - 1.7e-14 53.4 0.2 4.8e-14 51.9 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DUF3997 PF13162.1 CAM67019.1 - 0.43 10.3 0.0 0.78 9.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3997) Amidase PF01425.16 CAM67020.1 - 4.1e-58 197.3 0.0 2.3e-57 194.8 0.0 1.9 1 1 0 1 1 1 1 Amidase LSM PF01423.17 CAM67021.1 - 0.00068 19.1 0.0 0.00087 18.7 0.0 1.2 1 0 0 1 1 1 1 LSM domain Arf PF00025.16 CAM67022.1 - 3.5e-47 159.8 0.0 3.9e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CAM67022.1 - 5.8e-11 42.1 0.1 4.4e-09 36.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CAM67022.1 - 3e-10 39.6 0.0 3.9e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CAM67022.1 - 6.5e-09 35.3 0.0 7.4e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 CAM67022.1 - 1.3e-08 34.7 0.0 1.8e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CAM67022.1 - 6.9e-07 28.6 0.1 8.6e-07 28.3 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CAM67022.1 - 8.3e-07 29.5 0.0 1.1e-06 29.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 CAM67022.1 - 1.6e-06 27.0 2.9 0.0041 15.8 0.6 2.7 1 1 1 2 2 2 2 G-protein alpha subunit FeoB_N PF02421.13 CAM67022.1 - 0.00023 20.4 0.1 0.00043 19.6 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.1 CAM67022.1 - 0.00098 19.2 0.0 0.025 14.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain cobW PF02492.14 CAM67022.1 - 0.02 14.3 0.0 4 6.8 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 CAM67022.1 - 0.023 14.6 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 CAM67022.1 - 0.063 12.8 0.5 0.52 9.8 0.1 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 CAM67022.1 - 0.064 13.5 0.0 0.12 12.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 CAM67022.1 - 0.11 11.5 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Septin OTU PF02338.14 CAM67023.1 - 4.7e-16 59.4 0.0 9.5e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 CAM67023.1 - 0.0082 15.5 0.1 0.013 14.8 0.1 1.3 1 0 0 1 1 1 1 Peptidase C65 Otubain EMG1 PF03587.9 CAM67024.1 - 2.2e-74 249.1 0.0 2.8e-74 248.8 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase IQ PF00612.22 CAM67026.1 - 0.028 14.0 0.5 0.09 12.4 0.4 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif Suc_Fer-like PF06999.7 CAM67026.1 - 0.17 11.9 5.1 0.37 10.7 2.6 2.1 2 0 0 2 2 2 0 Sucrase/ferredoxin-like FlxA PF14282.1 CAM67026.1 - 3.7 7.5 10.8 20 5.1 5.4 3.0 1 1 1 2 2 2 0 FlxA-like protein DUF2229 PF09989.4 CAM67026.1 - 5.2 6.4 7.3 0.55 9.6 1.5 1.9 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF4407 PF14362.1 CAM67026.1 - 6.9 5.5 19.3 3.9 6.3 11.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) PAXIP1_C PF15364.1 CAM67027.1 - 0.024 14.5 4.1 0.05 13.5 2.8 1.6 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein PucR PF07905.6 CAM67027.1 - 0.091 12.3 0.1 2.2 7.8 0.1 2.3 2 0 0 2 2 2 0 Purine catabolism regulatory protein-like family V_ATPase_I PF01496.14 CAM67027.1 - 0.82 7.4 5.3 1 7.0 3.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Bap31 PF05529.7 CAM67027.1 - 2.1 7.7 12.3 3.8 6.9 8.5 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Flagellar_rod PF05149.7 CAM67028.1 - 3.3e-112 374.4 26.8 3.3e-112 374.4 18.5 2.1 2 0 0 2 2 2 1 Paraflagellar rod protein DUF1136 PF06582.7 CAM67028.1 - 0.14 11.8 3.8 0.15 11.8 0.8 2.5 2 0 0 2 2 2 0 Repeat of unknown function (DUF1136) SpoIISA_toxin PF14171.1 CAM67028.1 - 0.17 11.1 2.9 0.16 11.2 0.8 1.8 2 0 0 2 2 2 0 Toxin SpoIISA, type II toxin-antitoxin system CorA PF01544.13 CAM67028.1 - 4.3 6.2 15.4 0.38 9.7 1.8 3.6 3 1 0 3 3 3 0 CorA-like Mg2+ transporter protein PAPS_reduct PF01507.14 CAM67028.1 - 4.4 7.1 11.2 4.6 7.0 2.4 3.2 2 1 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family Flagellar_rod PF05149.7 CAM67029.2 - 8.7e-113 376.2 26.8 1.4e-112 375.5 18.5 1.3 1 0 0 1 1 1 1 Paraflagellar rod protein DUF1136 PF06582.7 CAM67029.2 - 0.12 12.0 3.8 0.1 12.2 0.8 2.3 2 0 0 2 2 2 0 Repeat of unknown function (DUF1136) SpoIISA_toxin PF14171.1 CAM67029.2 - 0.13 11.5 3.4 0.1 11.8 0.9 1.9 2 0 0 2 2 2 0 Toxin SpoIISA, type II toxin-antitoxin system PAPS_reduct PF01507.14 CAM67029.2 - 6.8 6.4 12.6 3.3 7.4 2.5 2.9 2 1 1 3 3 3 0 Phosphoadenosine phosphosulfate reductase family Kinesin PF00225.18 CAM67032.2 - 2.1e-78 263.4 0.0 1.4e-77 260.7 0.0 2.6 1 0 0 1 1 1 1 Kinesin motor domain Laminin_I PF06008.9 CAM67032.2 - 4.7e-69 232.6 543.6 0.00092 18.6 12.2 28.8 1 1 28 32 32 31 30 Laminin Domain I Spc7 PF08317.6 CAM67032.2 - 1.8e-31 109.0 484.2 0.00092 17.9 16.7 19.6 1 1 20 21 21 21 20 Spc7 kinetochore protein Laminin_II PF06009.7 CAM67032.2 - 2.9e-29 101.5 446.0 0.37 10.5 7.8 33.8 3 1 31 35 35 35 26 Laminin Domain II Tropomyosin PF00261.15 CAM67032.2 - 5.5e-22 78.0 634.1 0.052 12.6 28.5 16.0 1 1 15 16 16 15 14 Tropomyosin DUF3552 PF12072.3 CAM67032.2 - 1.7e-21 76.3 526.7 0.62 9.2 8.3 34.2 2 1 37 39 39 38 16 Domain of unknown function (DUF3552) Reo_sigmaC PF04582.7 CAM67032.2 - 4.4e-17 62.2 358.8 1.5 7.9 10.4 23.5 2 1 20 24 24 24 22 Reovirus sigma C capsid protein COG2 PF06148.6 CAM67032.2 - 7.6e-15 54.9 329.0 1.2 9.0 2.1 36.5 2 1 40 42 42 42 21 COG (conserved oligomeric Golgi) complex component, COG2 IFT57 PF10498.4 CAM67032.2 - 4.3e-12 45.4 416.4 0.68 8.6 10.6 25.6 1 1 26 29 29 29 16 Intra-flagellar transport protein 57 IncA PF04156.9 CAM67032.2 - 3.7e-11 42.9 583.0 0.74 9.3 13.7 20.3 1 1 8 10 10 7 1 IncA protein V-SNARE_C PF12352.3 CAM67032.2 - 3.4e-10 39.8 240.7 6.9 6.8 0.8 36.6 2 1 46 49 49 49 1 Snare region anchored in the vesicle membrane C-terminus DUF4200 PF13863.1 CAM67032.2 - 8.4e-07 28.9 497.4 1.4 8.8 11.8 30.9 1 1 37 39 39 39 9 Domain of unknown function (DUF4200) Atg14 PF10186.4 CAM67032.2 - 0.033 13.1 401.6 0.69 8.7 14.7 19.2 1 1 21 22 22 19 0 UV radiation resistance protein and autophagy-related subunit 14 Kinesin PF00225.18 CAM67034.1 - 8.4e-79 264.6 0.0 1.6e-78 263.8 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain TMF_DNA_bd PF12329.3 CAM67034.1 - 0.049 13.4 41.6 0.085 12.6 12.0 4.6 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding DFF40 PF09230.5 CAM67034.1 - 0.17 11.2 1.8 0.27 10.5 0.4 1.9 2 0 0 2 2 2 0 DNA fragmentation factor 40 kDa Spc7 PF08317.6 CAM67034.1 - 0.33 9.5 29.1 0.093 11.3 5.2 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein ResIII PF04851.10 CAM67034.1 - 0.38 10.5 4.5 9.3 6.0 0.0 3.1 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit DUF972 PF06156.8 CAM67034.1 - 0.55 10.6 31.0 2.7 8.3 6.4 5.3 2 1 3 5 5 5 0 Protein of unknown function (DUF972) Filament PF00038.16 CAM67034.1 - 0.67 9.3 43.7 0.2 11.0 16.2 2.7 1 1 1 2 2 2 0 Intermediate filament protein Sas10_Utp3 PF04000.10 CAM67034.1 - 0.92 9.7 9.2 6.7 6.9 0.3 4.5 4 0 0 4 4 4 0 Sas10/Utp3/C1D family CCDC84 PF14968.1 CAM67034.1 - 2.4 7.6 7.9 0.76 9.2 0.2 2.3 1 1 1 2 2 2 0 Coiled coil protein 84 Reo_sigmaC PF04582.7 CAM67034.1 - 4 6.5 12.9 12 4.9 0.2 3.3 2 1 1 3 3 3 0 Reovirus sigma C capsid protein AHS1 PF02682.11 CAM67034.1 - 5.6 6.3 7.8 0.98 8.8 0.8 2.9 2 1 0 3 3 3 0 Allophanate hydrolase subunit 1 Laminin_II PF06009.7 CAM67034.1 - 7.6 6.2 20.1 4.3 7.1 0.0 4.7 3 1 2 5 5 5 0 Laminin Domain II FtsH_ext PF06480.10 CAM67035.1 - 0.073 13.2 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 FtsH Extracellular Phage_term_sma PF07141.6 CAM67036.1 - 0.07 12.6 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Putative bacteriophage terminase small subunit Herpes_capsid PF06112.6 CAM67036.1 - 9.2 6.2 12.0 20 5.1 8.3 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein zf-met2 PF12907.2 CAM67038.1 - 2 8.4 4.2 24 5.0 0.7 2.4 2 0 0 2 2 2 0 Zinc-binding ERO1 PF04137.10 CAM67040.1 - 7.2e-96 321.3 0.0 8.4e-96 321.0 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DNA_pol_B PF00136.16 CAM67041.1 - 2.8e-119 398.9 0.0 4e-119 398.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CAM67041.1 - 1.4e-34 119.4 0.0 2.4e-34 118.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.5 CAM67041.1 - 0.2 10.9 4.8 0.67 9.2 1.6 2.3 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger WD40 PF00400.27 CAM67042.1 - 6.1e-22 76.6 3.0 0.00012 21.7 0.0 7.6 8 0 0 8 8 8 4 WD domain, G-beta repeat gpW PF02831.10 CAM67042.1 - 0.012 15.1 0.7 1.2 8.7 0.1 3.5 1 1 1 2 2 2 0 gpW KIP1 PF07765.7 CAM67042.1 - 0.076 12.8 4.8 0.12 12.2 0.5 3.2 2 1 1 3 3 3 0 KIP1-like protein PPR_3 PF13812.1 CAM67043.1 - 0.016 15.4 1.7 30 5.2 0.0 4.8 5 0 0 5 5 5 0 Pentatricopeptide repeat domain FAD_binding_8 PF08022.7 CAM67043.1 - 0.052 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 FAD-binding domain RRN3 PF05327.6 CAM67043.1 - 0.11 10.6 0.0 3.2 5.7 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Kinesin PF00225.18 CAM67045.1 - 2.1e-70 237.0 0.0 6.3e-40 136.8 0.0 2.2 2 0 0 2 2 2 2 Kinesin motor domain AAA_22 PF13401.1 CAM67045.1 - 0.9 9.6 3.9 20 5.3 0.2 2.6 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CAM67045.1 - 0.98 8.7 3.0 4.6 6.5 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain RRM_6 PF14259.1 CAM67046.1 - 1.5e-15 56.9 0.1 2.7e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAM67046.1 - 1.7e-13 49.9 0.0 2.6e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM67046.1 - 1.4e-05 24.8 0.0 2.6e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIF4G PF02854.14 CAM67047.1 - 2.1e-30 105.7 3.3 3e-30 105.2 2.3 1.2 1 0 0 1 1 1 1 MIF4G domain Band_7 PF01145.20 CAM67048.1 - 5.3e-22 78.5 1.9 5.3e-22 78.5 1.3 1.6 1 1 1 2 2 2 1 SPFH domain / Band 7 family DUF4200 PF13863.1 CAM67048.1 - 0.019 14.9 2.8 0.019 14.9 2.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) WD40 PF00400.27 CAM67049.1 - 5.5e-05 22.8 5.6 0.067 13.0 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 CAM67049.1 - 0.15 10.3 0.0 0.23 9.7 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain Nop PF01798.13 CAM67050.1 - 2.3e-12 46.4 1.3 9.5e-12 44.4 0.9 2.0 1 1 0 1 1 1 1 Putative snoRNA binding domain Prp31_C PF09785.4 CAM67050.1 - 0.0054 17.1 1.9 0.012 16.0 1.3 1.6 1 0 0 1 1 1 1 Prp31 C terminal domain TipAS PF07739.8 CAM67050.1 - 1.8 8.9 7.5 14 6.0 1.0 3.1 2 1 1 3 3 3 0 TipAS antibiotic-recognition domain TPR_12 PF13424.1 CAM67051.1 - 3.1e-09 36.6 12.5 0.15 12.0 0.0 7.0 5 1 0 6 6 6 3 Tetratricopeptide repeat eIF3_p135 PF12807.2 CAM67051.1 - 0.00075 19.4 0.0 0.0017 18.2 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_7 PF13176.1 CAM67051.1 - 0.034 13.9 1.5 18 5.4 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 CAM67051.1 - 0.05 13.2 16.3 0.23 11.1 0.1 5.9 7 0 0 7 7 7 0 TPR repeat IQ PF00612.22 CAM67051.1 - 0.078 12.6 10.6 1.4 8.7 1.3 4.4 3 0 0 3 3 3 0 IQ calmodulin-binding motif PPR_1 PF12854.2 CAM67051.1 - 4.6 6.8 7.3 4.1 6.9 0.0 3.5 4 0 0 4 4 4 0 PPR repeat CLU PF13236.1 CAM67052.1 - 4.3e-08 32.8 0.1 7e-06 25.6 0.0 2.9 1 1 1 2 2 2 1 Clustered mitochondria eIF3_p135 PF12807.2 CAM67052.1 - 6.5e-05 22.9 0.0 0.0001 22.2 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 CLU PF13236.1 CAM67053.1 - 3.1e-09 36.6 0.2 3.5e-08 33.1 0.1 2.3 1 1 0 1 1 1 1 Clustered mitochondria IucA_IucC PF04183.7 CAM67053.1 - 0.00034 19.9 28.1 6.9 5.8 0.3 8.5 2 1 6 8 8 8 7 IucA / IucC family eIF3_p135 PF12807.2 CAM67053.1 - 0.0031 17.4 0.0 0.0075 16.2 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 DUF1343 PF07075.6 CAM67053.1 - 0.068 12.0 0.0 1.8e+02 0.7 0.0 5.6 9 0 0 9 9 9 0 Protein of unknown function (DUF1343) DUF318 PF03773.8 CAM67053.1 - 2.9 6.7 0.0 4.9 6.0 0.0 1.2 1 0 0 1 1 1 0 Predicted permease PPR_2 PF13041.1 CAM67054.1 - 2.5e-49 165.0 16.2 3.6e-08 33.2 0.0 14.5 10 3 6 16 16 16 10 PPR repeat family PPR PF01535.15 CAM67054.1 - 6.2e-44 144.9 22.1 0.00035 20.3 0.0 18.3 19 0 0 19 19 19 11 PPR repeat PPR_3 PF13812.1 CAM67054.1 - 8e-36 119.3 15.9 0.29 11.5 0.0 19.7 21 1 0 21 21 21 9 Pentatricopeptide repeat domain PPR_1 PF12854.2 CAM67054.1 - 3.6e-17 61.5 11.6 0.064 12.7 0.0 11.9 14 0 0 14 14 14 4 PPR repeat TPR_14 PF13428.1 CAM67054.1 - 1.2e-05 25.5 3.6 7 7.5 0.1 7.1 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 CAM67054.1 - 5.2e-05 23.8 0.7 0.66 10.7 1.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 CAM67054.1 - 0.00021 21.1 3.1 3 7.8 0.8 5.3 5 1 2 7 7 7 3 Tetratricopeptide repeat RNA_pol_Rpb4 PF03874.11 CAM67054.1 - 0.037 14.0 0.0 5.2 7.1 0.0 4.1 5 0 0 5 5 5 0 RNA polymerase Rpb4 GHMP_kinases_N PF00288.21 CAM67055.1 - 8.9e-07 28.8 2.4 2.5e-06 27.4 1.6 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain RRM_5 PF13893.1 CAM67056.1 - 9.1e-07 28.6 0.0 2.4e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAM67056.1 - 2.9e-06 26.8 0.0 4.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM67056.1 - 0.0067 16.3 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CAM67056.1 - 0.068 12.9 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif MFS_1 PF07690.11 CAM67057.2 - 6.3e-22 77.7 45.7 6.3e-22 77.7 31.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CAM67057.2 - 1.9e-09 36.6 13.4 1.9e-09 36.6 9.3 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 CAM67057.2 - 1.7e-08 32.9 16.1 0.00017 19.8 0.7 3.3 2 1 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family zf-C2HC_2 PF13913.1 CAM67060.1 - 2.7e-43 144.8 51.8 1.5e-09 37.3 1.7 8.4 8 0 0 8 8 8 6 zinc-finger of a C2HC-type zf-ribbon_3 PF13248.1 CAM67060.1 - 1.3e-17 62.4 49.6 3e-05 23.0 1.1 9.2 9 0 0 9 9 9 4 zinc-ribbon domain DZR PF12773.2 CAM67060.1 - 2.3e-16 59.3 56.6 1e-11 44.4 7.5 8.6 7 2 0 7 7 7 3 Double zinc ribbon zinc_ribbon_2 PF13240.1 CAM67060.1 - 2.7e-13 48.9 45.8 0.00049 19.4 0.7 8.8 8 0 0 8 8 8 4 zinc-ribbon domain NOB1_Zn_bind PF08772.6 CAM67060.1 - 3.7e-05 23.4 27.8 0.00045 19.9 0.2 5.7 4 1 1 5 5 5 3 Nin one binding (NOB1) Zn-ribbon like UPF0547 PF10571.4 CAM67060.1 - 0.0004 20.0 3.5 0.0004 20.0 2.4 10.3 10 1 0 10 10 10 1 Uncharacterised protein family UPF0547 zinc-ribbons_6 PF07191.7 CAM67060.1 - 0.064 13.0 0.4 0.064 13.0 0.2 7.8 9 1 0 9 9 9 0 zinc-ribbons zf-dskA_traR PF01258.12 CAM67060.1 - 3.7 7.3 26.2 0.3 10.8 1.5 6.2 6 0 0 6 6 6 0 Prokaryotic dksA/traR C4-type zinc finger Cript PF10235.4 CAM67060.1 - 8.4 6.8 24.1 7.8 6.9 0.5 5.9 6 1 1 7 7 7 0 Microtubule-associated protein CRIPT 3Beta_HSD PF01073.14 CAM67061.1 - 3.9e-10 38.8 0.0 5.7e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CAM67061.1 - 9.1e-08 32.3 0.0 1.5e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 CAM67061.1 - 3.5e-05 24.1 0.0 7.9e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 CAM67061.1 - 0.00014 20.8 0.0 0.11 11.3 0.0 3.3 3 1 0 3 3 3 2 RmlD substrate binding domain adh_short PF00106.20 CAM67061.1 - 0.0016 18.3 0.0 0.0044 16.9 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 CAM67061.1 - 0.0039 16.4 0.0 0.006 15.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family DapB_N PF01113.15 CAM67061.1 - 0.015 15.1 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 CAM67061.1 - 0.038 13.4 0.1 0.089 12.2 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Glyco_hydro_31 PF01055.21 CAM67062.1 - 1.8e-148 495.0 1.9 2.2e-148 494.7 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CAM67062.1 - 4.3e-17 61.7 0.1 2e-16 59.5 0.1 2.2 1 0 0 1 1 1 1 Galactose mutarotase-like DUF726 PF05277.7 CAM67064.1 - 8.2e-53 179.4 24.2 1.8e-50 171.7 0.0 3.2 2 1 1 3 3 3 2 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 CAM67064.1 - 0.0013 18.7 0.0 0.004 17.0 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family VirJ PF06057.6 CAM67064.1 - 0.07 12.9 0.0 14 5.4 0.0 2.4 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) Abhydrolase_5 PF12695.2 CAM67064.1 - 0.13 11.9 0.0 0.13 11.9 0.0 2.5 2 1 0 2 2 2 0 Alpha/beta hydrolase family Ssl1 PF04056.9 CAM67064.1 - 0.2 11.2 0.0 30 4.1 0.0 2.9 3 0 0 3 3 3 0 Ssl1-like DUF21 PF01595.15 CAM67066.1 - 3.2e-27 94.9 2.1 7e-27 93.8 1.5 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 CAM67066.1 - 2.1e-09 36.9 1.1 2.3e-05 24.0 0.0 3.4 3 0 0 3 3 3 2 CBS domain cNMP_binding PF00027.24 CAM67066.1 - 0.045 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain DUF21 PF01595.15 CAM67067.1 - 1.1e-34 119.3 2.0 2.7e-34 118.0 0.3 2.1 1 1 1 2 2 2 1 Domain of unknown function DUF21 CBS PF00571.23 CAM67067.1 - 0.00085 19.0 0.1 3.9 7.3 0.0 3.4 3 0 0 3 3 3 2 CBS domain cNMP_binding PF00027.24 CAM67067.1 - 0.0051 16.5 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Metallophos PF00149.23 CAM67068.1 - 8.8e-39 132.9 0.2 1.3e-38 132.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 CAM67068.1 - 1.3e-23 82.8 1.2 2.2e-23 82.0 0.1 1.9 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_11 PF13414.1 CAM67068.1 - 1.5e-19 69.4 4.3 1.2e-14 53.7 0.4 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 CAM67068.1 - 6.7e-17 60.3 3.0 6.9e-05 22.2 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CAM67068.1 - 6.1e-14 50.7 4.1 0.00038 20.1 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 CAM67068.1 - 7.1e-06 25.8 0.5 0.00016 21.6 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CAM67068.1 - 1.1e-05 24.8 1.6 0.53 10.1 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CAM67068.1 - 1.9e-05 25.1 4.3 0.00073 20.1 1.2 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CAM67068.1 - 0.00019 21.8 1.5 0.057 14.0 0.1 3.2 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CAM67068.1 - 0.00026 20.8 2.4 0.015 15.2 0.1 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 CAM67068.1 - 0.00029 21.1 0.9 0.0049 17.1 0.2 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 CAM67068.1 - 0.026 14.3 0.2 0.94 9.3 0.1 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 CAM67068.1 - 0.038 13.7 0.2 11 6.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Paf67 PF10255.4 CAM67068.1 - 0.1 11.4 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 TPR_6 PF13174.1 CAM67068.1 - 0.16 12.4 1.9 3.2 8.4 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 CAM67068.1 - 0.64 10.1 5.3 11 6.2 0.2 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Lipase_3 PF01764.20 CAM67069.1 - 5.4e-12 45.5 0.0 9.8e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 CAM67069.1 - 3.5e-05 23.7 0.4 0.00023 21.1 0.0 2.3 3 0 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CAM67069.1 - 0.0061 16.3 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Na_Ca_ex PF01699.19 CAM67069.1 - 0.037 13.6 1.4 0.075 12.6 1.0 1.5 1 0 0 1 1 1 0 Sodium/calcium exchanger protein Totivirus_coat PF05518.6 CAM67069.1 - 0.098 10.4 0.0 0.16 9.7 0.0 1.2 1 0 0 1 1 1 0 Totivirus coat protein PGAP1 PF07819.8 CAM67069.1 - 0.21 11.1 0.1 0.36 10.3 0.1 1.3 1 0 0 1 1 1 0 PGAP1-like protein RRM_1 PF00076.17 CAM67070.1 - 6.1e-28 96.2 0.0 3.3e-17 61.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM67070.1 - 5.7e-22 77.4 0.0 1.7e-11 43.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM67070.1 - 2.2e-13 49.8 0.0 1.3e-08 34.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 CAM67070.1 - 0.0014 18.1 0.0 0.0063 16.1 0.0 1.9 2 0 0 2 2 2 1 Calcipressin Nup35_RRM_2 PF14605.1 CAM67070.1 - 0.011 15.5 0.0 0.95 9.2 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 CAM67070.1 - 0.014 15.1 0.0 0.045 13.5 0.0 1.9 2 0 0 2 2 2 0 Limkain b1 Phosphoprotein PF00922.12 CAM67070.1 - 0.06 12.5 1.1 0.096 11.8 0.8 1.2 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein RRM_1 PF00076.17 CAM67071.1 - 5.5e-28 96.4 0.0 3.3e-17 61.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM67071.1 - 6e-22 77.4 0.0 1.8e-11 43.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM67071.1 - 3.1e-13 49.3 0.0 1.3e-08 34.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 CAM67071.1 - 0.0015 18.1 0.0 0.0063 16.1 0.0 1.8 2 0 0 2 2 2 1 Calcipressin Nup35_RRM_2 PF14605.1 CAM67071.1 - 0.0098 15.6 0.0 0.96 9.2 0.0 2.5 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 CAM67071.1 - 0.013 15.2 0.0 0.045 13.5 0.0 2.0 2 0 0 2 2 2 0 Limkain b1 DUF1264 PF06884.6 CAM67071.1 - 0.06 12.7 0.0 6.8 6.1 0.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1264) RRM_1 PF00076.17 CAM67072.1 - 8.3e-30 102.2 0.1 5.8e-18 64.2 0.0 2.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM67072.1 - 3.1e-19 68.6 0.1 1e-09 38.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM67072.1 - 2e-10 40.3 0.0 1.3e-07 31.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CAM67072.1 - 0.0037 17.0 0.0 0.74 9.6 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif NAD_binding_8 PF13450.1 CAM67073.1 - 1.8e-08 34.2 2.3 4.3e-08 33.0 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 CAM67073.1 - 2.9e-07 29.9 0.1 0.00021 20.5 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 CAM67073.1 - 0.00023 21.3 0.0 0.0005 20.2 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CAM67073.1 - 0.0026 17.5 0.5 0.015 15.1 0.1 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 CAM67073.1 - 0.0083 15.0 0.1 0.018 13.9 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CAM67073.1 - 0.03 14.2 0.2 0.077 12.8 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CAM67073.1 - 0.12 10.8 0.3 0.19 10.1 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein DUF1651 PF07864.6 CAM67073.1 - 0.13 12.4 0.2 0.27 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1651) ThiF PF00899.16 CAM67073.1 - 0.13 12.1 1.4 0.25 11.1 0.1 2.2 2 0 0 2 2 2 0 ThiF family Aha1_N PF09229.6 CAM67074.1 - 1.2e-33 115.8 0.4 1.7e-33 115.3 0.3 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 CAM67074.1 - 1.4e-18 67.1 0.0 9.2e-18 64.5 0.0 2.1 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Vac_ImportDeg PF09783.4 CAM67074.1 - 0.088 12.2 0.0 0.21 11.0 0.0 1.7 1 0 0 1 1 1 0 Vacuolar import and degradation protein RRM_1 PF00076.17 CAM67075.1 - 5.3e-12 45.1 0.0 8.5e-12 44.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM67075.1 - 8e-12 44.9 0.0 1.5e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM67075.1 - 2.2e-06 27.4 0.0 5.1e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metal_resist PF13801.1 CAM67075.1 - 0.66 9.9 10.2 0.49 10.3 0.1 2.8 3 0 0 3 3 3 0 Heavy-metal resistance Vfa1 PF08432.5 CAM67075.1 - 0.67 9.9 9.2 0.94 9.4 6.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Ribosomal_L30 PF00327.15 CAM67076.1 - 0.0021 17.5 0.0 0.0059 16.1 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Pkinase PF00069.20 CAM67080.1 - 1.9e-55 187.8 0.0 2.3e-55 187.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM67080.1 - 1.6e-23 83.1 0.0 2.8e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CAM67080.1 - 0.0011 18.7 0.3 0.0045 16.7 0.0 2.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CAM67080.1 - 0.0028 17.2 0.1 0.0057 16.2 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 CAM67080.1 - 0.099 11.7 0.0 0.23 10.4 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Phage_int_SAM_1 PF02899.12 CAM67081.1 - 3.1 8.0 8.1 8.6 6.5 0.1 4.3 5 0 0 5 5 5 0 Phage integrase, N-terminal SAM-like domain DUF4404 PF14357.1 CAM67081.1 - 9.5 6.7 7.8 1.3 9.5 1.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) CoaE PF01121.15 CAM67082.1 - 6.3e-22 77.8 1.2 1.3e-06 27.9 0.3 4.1 4 0 0 4 4 4 4 Dephospho-CoA kinase GTP_EFTU PF00009.22 CAM67082.1 - 0.024 14.0 0.1 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 CAM67082.1 - 0.18 12.1 0.4 0.77 10.0 0.1 2.0 2 0 0 2 2 2 0 AAA domain RRM_6 PF14259.1 CAM67083.1 - 0.0003 20.7 0.0 0.00077 19.3 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAM67083.1 - 0.13 11.9 0.0 0.43 10.2 0.0 1.9 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DnaJ PF00226.26 CAM67086.2 - 7.4e-17 60.8 0.0 1.3e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DUF446 PF04287.7 CAM67086.2 - 0.052 13.3 0.1 0.092 12.5 0.1 1.3 1 0 0 1 1 1 0 tRNA pseudouridine synthase C Mpp10 PF04006.7 CAM67086.2 - 0.21 9.8 1.5 0.29 9.4 1.1 1.1 1 0 0 1 1 1 0 Mpp10 protein DUF4475 PF14753.1 CAM67087.1 - 2.7e-16 59.6 11.0 1.5e-13 50.6 1.2 3.2 3 0 0 3 3 3 3 Domain of unknown function (DUF4475) NOB1_Zn_bind PF08772.6 CAM67087.1 - 0.022 14.5 1.5 0.022 14.5 1.1 2.6 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like zf-DHHC PF01529.15 CAM67087.1 - 0.11 11.9 0.0 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF2616 PF11077.3 CAM67087.1 - 0.17 11.3 3.8 0.31 10.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2616) Cript PF10235.4 CAM67087.1 - 0.48 10.8 0.1 0.48 10.8 0.1 3.1 3 0 0 3 3 3 0 Microtubule-associated protein CRIPT DZR PF12773.2 CAM67087.1 - 3.7 7.4 19.0 0.054 13.3 0.9 3.6 3 1 0 3 3 3 0 Double zinc ribbon ATP12 PF07542.6 CAM67088.1 - 8.8e-27 93.4 0.0 1.5e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein Peptidase_C13 PF01650.13 CAM67089.1 - 9.9e-40 136.4 1.0 9.9e-40 136.4 0.0 1.4 2 0 0 2 2 2 1 Peptidase C13 family TTL PF03133.10 CAM67090.1 - 1.9e-75 253.4 0.0 2.7e-75 253.0 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 CAM67090.1 - 0.00019 20.3 0.0 0.0077 15.0 0.0 2.8 3 0 0 3 3 3 1 YheC/D like ATP-grasp DUF3884 PF13024.1 CAM67090.1 - 0.055 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3884) Nuc_sug_transp PF04142.10 CAM67093.1 - 4.6e-60 202.7 6.2 4.6e-60 202.7 4.3 2.2 2 1 0 2 2 2 1 Nucleotide-sugar transporter TPT PF03151.11 CAM67093.1 - 1e-07 31.7 14.7 1.1e-07 31.6 2.3 3.4 3 0 0 3 3 3 2 Triose-phosphate Transporter family EamA PF00892.15 CAM67093.1 - 1.4e-06 28.3 5.0 1.4e-06 28.3 3.5 3.0 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 CAM67093.1 - 0.0036 17.4 3.9 0.0036 17.4 2.7 3.0 3 0 0 3 3 3 1 Multidrug resistance efflux transporter UAA PF08449.6 CAM67093.1 - 2 7.2 11.4 0.43 9.4 0.6 2.8 3 1 0 3 3 3 0 UAA transporter family OGFr_III PF04680.8 CAM67094.1 - 6.2 7.1 9.4 0.53 10.4 1.8 2.7 3 0 0 3 3 3 0 Opioid growth factor receptor repeat PAP2 PF01569.16 CAM67096.1 - 2.3e-17 62.9 1.3 2.3e-17 62.9 0.9 2.0 2 1 0 2 2 2 1 PAP2 superfamily DUF2069 PF09842.4 CAM67096.1 - 0.0043 16.9 1.5 0.085 12.8 0.4 2.4 2 0 0 2 2 2 1 Predicted membrane protein (DUF2069) PAP2 PF01569.16 CAM67097.1 - 1.9e-17 63.1 3.9 1.9e-17 63.1 2.7 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 CAM67097.1 - 0.012 15.0 0.7 0.061 12.8 0.2 2.2 1 1 0 1 1 1 0 PAP2 superfamily Peptidase_S10 PF00450.17 CAM67098.1 - 9.1e-110 367.6 0.4 1.1e-109 367.3 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 CAM67098.1 - 1.2e-05 25.3 0.0 3.2e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family CAP_GLY PF01302.20 CAM67099.1 - 4.1e-22 77.6 0.3 6.9e-22 76.9 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 CAM67099.1 - 4.7e-22 78.0 0.0 8.3e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 CAM67099.1 - 0.024 14.0 0.0 0.18 11.2 0.0 2.1 1 1 0 1 1 1 0 Ubiquitin family WD40 PF00400.27 CAM67100.1 - 6.5e-56 184.3 23.4 1.6e-10 40.4 0.5 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CAM67100.1 - 0.005 15.0 2.7 0.8 7.7 0.0 2.4 1 1 1 2 2 2 2 Nucleoporin Nup120/160 CENP-F_leu_zip PF10473.4 CAM67100.1 - 0.13 12.1 18.2 0.2 11.5 12.6 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 CAM67100.1 - 0.17 11.4 5.6 0.25 10.8 3.9 1.2 1 0 0 1 1 1 0 IncA protein DUF904 PF06005.7 CAM67100.1 - 2.9 8.2 11.4 10 6.4 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF904) TPR_MLP1_2 PF07926.7 CAM67100.1 - 4.8 6.9 14.2 9 6.0 9.9 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein UDG PF03167.14 CAM67101.1 - 2e-21 76.0 0.0 3.2e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily BTB_2 PF02214.17 CAM67102.1 - 1.7e-13 50.5 0.0 2.7e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain PPR_2 PF13041.1 CAM67103.1 - 0.0028 17.5 0.0 1.1 9.3 0.0 3.2 3 0 0 3 3 3 1 PPR repeat family XRCC1_N PF01834.11 CAM67103.1 - 0.046 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 XRCC1 N terminal domain PPR_3 PF13812.1 CAM67103.1 - 0.098 12.9 1.6 55 4.4 0.0 4.3 4 0 0 4 4 4 0 Pentatricopeptide repeat domain PPR_1 PF12854.2 CAM67103.1 - 0.12 11.9 0.1 0.41 10.1 0.0 2.0 2 0 0 2 2 2 0 PPR repeat Aconitase PF00330.15 CAM67104.1 - 1.9e-142 475.0 0.0 2.6e-142 474.6 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CAM67104.1 - 1.4e-41 141.6 0.0 3.4e-41 140.4 0.0 1.7 1 0 0 1 1 1 1 Aconitase C-terminal domain Lectin_N PF03954.9 CAM67105.1 - 0.36 10.2 2.1 5 6.5 0.0 3.0 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain CASP_C PF08172.7 CAM67105.1 - 0.79 8.7 18.1 0.0093 15.0 6.1 2.5 2 1 0 2 2 2 0 CASP C terminal Mnd1 PF03962.10 CAM67105.1 - 1.1 8.8 28.9 0.27 10.8 2.0 3.2 3 0 0 3 3 3 0 Mnd1 family APG6 PF04111.7 CAM67105.1 - 6.9 5.6 26.7 0.51 9.3 3.3 3.1 3 0 0 3 3 3 0 Autophagy protein Apg6 TBCC PF07986.7 CAM67106.1 - 1.5e-33 114.7 0.1 2.3e-33 114.1 0.1 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C FOP_dimer PF09398.5 CAM67106.1 - 8.3e-05 22.5 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 FOP N terminal dimerisation domain CAP_C PF08603.6 CAM67106.1 - 0.031 13.6 0.1 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal BNR_2 PF13088.1 CAM67108.1 - 0.081 12.2 0.0 0.19 11.0 0.0 1.5 1 1 1 2 2 2 0 BNR repeat-like domain Atrophin-1 PF03154.10 CAM67108.1 - 4.1 5.4 6.9 4.4 5.3 4.8 1.1 1 0 0 1 1 1 0 Atrophin-1 family V-ATPase_C PF03223.10 CAM67109.1 - 6.8e-93 311.5 0.6 8.1e-93 311.2 0.4 1.0 1 0 0 1 1 1 1 V-ATPase subunit C PapD-like PF14874.1 CAM67110.1 - 6.2e-11 42.1 6.7 0.0075 16.1 0.1 5.1 5 0 0 5 5 5 4 Flagellar-associated PapD-like Motile_Sperm PF00635.21 CAM67110.1 - 0.0002 20.9 0.3 0.038 13.6 0.0 4.2 5 0 0 5 5 5 1 MSP (Major sperm protein) domain PapD_N PF00345.15 CAM67110.1 - 0.0004 20.1 0.4 2.1 8.1 0.0 4.2 6 1 0 6 6 6 2 Pili and flagellar-assembly chaperone, PapD N-terminal domain ECH PF00378.15 CAM67111.1 - 2.8e-32 111.8 0.8 6.3e-30 104.0 0.6 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family RRM_1 PF00076.17 CAM67112.1 - 8e-17 60.6 0.0 1.6e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM67112.1 - 5.3e-12 45.5 0.0 9.8e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM67112.1 - 6.2e-10 38.7 0.0 1.4e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CAM67112.1 - 0.052 13.3 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif FYVE PF01363.16 CAM67114.1 - 1.1e-19 70.0 8.6 1.1e-19 70.0 5.9 4.8 3 2 0 3 3 3 1 FYVE zinc finger zf-RanBP PF00641.13 CAM67114.1 - 1.8e-15 55.7 62.1 4e-07 29.0 0.7 6.7 7 0 0 7 7 7 5 Zn-finger in Ran binding protein and others DZR PF12773.2 CAM67114.1 - 0.00042 20.0 48.2 0.044 13.6 3.9 5.7 3 2 2 5 5 5 4 Double zinc ribbon Peptidase_M41 PF01434.13 CAM67115.1 - 1.4e-48 165.2 2.2 1.9e-48 164.7 1.5 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CAM67115.1 - 1.3e-39 135.3 0.0 2.4e-39 134.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CAM67115.1 - 1.6e-05 24.9 1.3 0.00044 20.2 0.1 2.9 1 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 CAM67115.1 - 9.6e-05 22.5 0.1 0.0016 18.5 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CAM67115.1 - 0.00036 20.2 0.1 0.0016 18.1 0.1 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_2 PF07724.9 CAM67115.1 - 0.00079 19.3 0.3 0.0042 17.0 0.2 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CAM67115.1 - 0.00085 19.0 0.2 0.0062 16.2 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CAM67115.1 - 0.0014 19.4 0.1 0.0046 17.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CAM67115.1 - 0.0035 16.7 1.7 0.048 13.0 0.2 2.4 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 CAM67115.1 - 0.0081 15.2 0.1 0.045 12.7 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CAM67115.1 - 0.01 15.7 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Peptidase_M50B PF13398.1 CAM67115.1 - 0.014 14.7 0.1 0.029 13.7 0.1 1.4 1 0 0 1 1 1 0 Peptidase M50B-like Sigma54_activat PF00158.21 CAM67115.1 - 0.016 14.7 0.1 0.064 12.7 0.1 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 CAM67115.1 - 0.019 14.3 0.2 0.038 13.3 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 CAM67115.1 - 0.024 13.7 0.2 0.26 10.3 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin DUF2075 PF09848.4 CAM67115.1 - 0.05 12.5 0.1 0.077 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 CAM67115.1 - 0.053 13.1 0.2 0.73 9.4 0.1 2.5 2 0 0 2 2 2 0 NACHT domain TIP49 PF06068.8 CAM67115.1 - 0.054 12.2 0.0 0.13 11.0 0.0 1.5 1 0 0 1 1 1 0 TIP49 C-terminus NTPase_1 PF03266.10 CAM67115.1 - 0.15 11.7 0.1 0.83 9.3 0.0 2.1 2 0 0 2 2 2 0 NTPase KaiC PF06745.8 CAM67115.1 - 0.16 11.0 1.0 0.23 10.5 0.0 1.7 2 0 0 2 2 2 0 KaiC Ribosomal_L1 PF00687.16 CAM67116.1 - 5e-47 160.0 3.6 5.8e-47 159.8 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Pkinase PF00069.20 CAM67118.1 - 5.1e-74 248.7 0.0 5.7e-74 248.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM67118.1 - 2.7e-39 134.7 0.0 3.3e-39 134.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM67118.1 - 1.1e-10 40.9 0.0 1.4e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CAM67118.1 - 5.8e-06 26.2 0.1 0.046 13.4 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CAM67118.1 - 0.0043 16.1 0.1 0.0066 15.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CAM67118.1 - 0.03 13.6 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family DUF421 PF04239.7 CAM67118.1 - 0.06 12.8 1.8 0.15 11.6 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF421) YukC PF10140.4 CAM67118.1 - 0.075 11.6 0.0 0.097 11.2 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Phosducin PF02114.11 CAM67118.1 - 0.077 11.7 0.1 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Phosducin Choline_kinase PF01633.15 CAM67118.1 - 0.093 12.2 0.0 0.2 11.2 0.0 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.6 CAM67118.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 PA26 PF04636.8 CAM67119.2 - 1.3e-30 106.5 1.9 7e-11 41.4 0.0 3.1 3 0 0 3 3 3 3 PA26 p53-induced protein (sestrin) HEAT PF02985.17 CAM67120.1 - 4.7e-22 76.0 17.8 0.00087 19.1 0.0 10.7 11 0 0 11 11 11 7 HEAT repeat HEAT_2 PF13646.1 CAM67120.1 - 8.1e-20 70.9 17.6 3.3e-06 27.2 0.0 6.9 4 3 3 7 7 7 6 HEAT repeats HEAT_EZ PF13513.1 CAM67120.1 - 1.4e-05 25.3 15.0 0.0079 16.6 0.0 7.3 7 1 2 9 9 9 2 HEAT-like repeat Adaptin_N PF01602.15 CAM67120.1 - 0.0012 17.3 0.3 2.3 6.4 0.1 3.5 3 1 0 5 5 5 2 Adaptin N terminal region CLASP_N PF12348.3 CAM67120.1 - 0.0019 17.6 0.1 8.4 5.6 0.0 3.7 2 1 2 4 4 4 2 CLASP N terminal Leuk-A4-hydro_C PF09127.6 CAM67120.1 - 0.063 12.8 0.0 0.25 10.9 0.0 2.0 2 0 0 2 2 2 0 Leukotriene A4 hydrolase, C-terminal DUF3778 PF12620.3 CAM67121.1 - 0.13 11.8 0.0 0.32 10.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3778) Citrate_synt PF00285.16 CAM67122.1 - 9.9e-104 346.8 0.0 1.2e-103 346.5 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Cyclin_C PF02984.14 CAM67122.1 - 0.037 13.9 0.1 0.1 12.5 0.1 1.7 1 0 0 1 1 1 0 Cyclin, C-terminal domain zf-AN1 PF01428.11 CAM67122.1 - 0.14 12.0 1.3 0.29 11.0 0.9 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger Citrate_synt PF00285.16 CAM67123.1 - 2.5e-102 342.2 0.0 3e-102 341.9 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase AAA_16 PF13191.1 CAM67125.1 - 0.002 18.1 0.3 0.002 18.1 0.2 4.0 4 1 1 5 5 5 1 AAA ATPase domain Tom5 PF10642.4 CAM67125.1 - 0.054 13.1 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase Seryl_tRNA_N PF02403.17 CAM67125.1 - 0.073 13.0 0.3 0.15 12.0 0.2 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Tctex-1 PF03645.8 CAM67126.1 - 2.9e-21 75.2 0.1 8.5e-21 73.7 0.0 1.7 2 0 0 2 2 2 1 Tctex-1 family Bd3614_N PF14442.1 CAM67126.1 - 5.7 6.9 10.8 0.22 11.5 3.1 1.8 2 1 0 2 2 2 0 Bd3614-like deaminase N-terminal AATF-Che1 PF13339.1 CAM67128.1 - 0.34 11.0 3.9 0.29 11.2 0.3 2.4 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor zf-C2H2_jaz PF12171.3 CAM67129.1 - 1.5e-09 37.7 1.5 2.9e-09 36.7 1.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CAM67129.1 - 1.3e-07 31.5 0.6 2.2e-07 30.8 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CAM67129.1 - 0.0038 17.3 0.6 0.0052 16.8 0.4 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 CAM67129.1 - 0.054 13.8 0.4 0.11 12.8 0.3 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Fer4_18 PF13746.1 CAM67129.1 - 0.094 13.1 0.1 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 4Fe-4S dicluster domain zf-C2H2_4 PF13894.1 CAM67129.1 - 0.11 12.8 0.8 0.26 11.7 0.6 1.7 1 1 0 1 1 1 0 C2H2-type zinc finger zf-DBF PF07535.7 CAM67129.1 - 0.14 11.8 1.0 0.21 11.3 0.7 1.3 1 0 0 1 1 1 0 DBF zinc finger zf-C2H2_6 PF13912.1 CAM67129.1 - 0.16 11.8 4.9 0.88 9.5 3.4 2.1 1 1 0 1 1 1 0 C2H2-type zinc finger zf-U1 PF06220.7 CAM67129.1 - 0.21 11.1 1.1 0.36 10.4 0.7 1.3 1 0 0 1 1 1 0 U1 zinc finger PDZ_2 PF13180.1 CAM67130.1 - 0.014 15.2 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.19 CAM67130.1 - 0.068 13.3 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) RNA_pol_Rpb5_C PF01191.14 CAM67131.1 - 2.4e-31 107.1 0.2 4.4e-31 106.3 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 CAM67131.1 - 2.7e-13 50.1 0.0 1.1e-12 48.1 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain RNA_pol_Rpb5_C PF01191.14 CAM67132.1 - 1.3e-24 85.5 0.0 2.4e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 CAM67132.1 - 2.7e-08 34.1 0.0 6.8e-05 23.1 0.0 2.4 2 0 0 2 2 2 2 RNA polymerase Rpb5, N-terminal domain Ribosomal_S8 PF00410.14 CAM67133.1 - 1.8e-11 44.0 0.0 2.6e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 CDP-OH_P_transf PF01066.16 CAM67134.1 - 1.1e-26 93.1 1.7 1.1e-26 93.1 1.1 3.0 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase HEAT PF02985.17 CAM67135.1 - 2.3e-05 24.0 10.3 0.09 12.9 0.1 7.9 8 0 0 8 8 8 2 HEAT repeat HEAT_EZ PF13513.1 CAM67135.1 - 0.0032 17.9 27.9 0.023 15.1 1.0 9.4 8 1 1 9 9 9 3 HEAT-like repeat Cnd1 PF12717.2 CAM67135.1 - 0.0079 16.0 1.6 14 5.5 0.0 4.7 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 CAM67135.1 - 0.043 14.1 1.1 40 4.6 0.0 5.2 6 0 0 6 6 6 0 Vacuolar 14 Fab1-binding region WD40 PF00400.27 CAM67136.2 - 6.4e-29 98.7 20.5 1.3e-08 34.3 0.1 12.2 13 0 0 13 13 13 6 WD domain, G-beta repeat Utp12 PF04003.7 CAM67136.2 - 2.1e-07 30.7 0.0 5e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Dip2/Utp12 Family DUF1513 PF07433.6 CAM67136.2 - 0.0034 16.3 1.0 0.29 10.0 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1513) Pol_alpha_B_N PF08418.5 CAM67139.1 - 0.94 8.9 4.1 0.78 9.2 0.8 2.1 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Sorting_nexin PF03700.8 CAM67140.1 - 0.017 15.2 1.0 0.036 14.1 0.7 1.6 1 0 0 1 1 1 0 Sorting nexin, N-terminal domain XAP5 PF04921.9 CAM67140.1 - 0.13 11.7 1.2 0.2 11.1 0.9 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator Pro_isomerase PF00160.16 CAM67141.1 - 1.1e-33 116.6 0.0 2.4e-33 115.5 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Glyco_trans_1_4 PF13692.1 CAM67143.1 - 2.4e-10 40.7 0.0 2e-09 37.6 0.0 2.6 2 1 0 2 2 2 1 Glycosyl transferases group 1 PPR_2 PF13041.1 CAM67144.1 - 0.0093 15.9 0.0 3.2 7.7 0.0 3.4 2 1 1 3 3 3 1 PPR repeat family PPR PF01535.15 CAM67144.1 - 0.056 13.4 0.1 10 6.3 0.0 3.6 4 0 0 4 4 4 0 PPR repeat PPR_3 PF13812.1 CAM67144.1 - 2.1 8.8 16.6 54 4.4 0.1 7.8 7 1 0 7 7 7 0 Pentatricopeptide repeat domain WD40 PF00400.27 CAM67145.1 - 1.8e-11 43.4 9.1 0.0081 16.0 0.4 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat PD40 PF07676.7 CAM67145.1 - 0.02 14.5 0.0 1.5 8.6 0.0 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Myosin_TH1 PF06017.8 CAM67146.1 - 0.068 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Myosin tail GAS PF13851.1 CAM67146.1 - 5.1 6.2 15.8 0.47 9.6 6.6 1.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Nrap PF03813.9 CAM67147.2 - 2.8e-65 220.4 0.0 5.2e-65 219.6 0.0 1.3 1 0 0 1 1 1 1 Nrap protein Mannosyl_trans2 PF04188.8 CAM67149.1 - 1.1e-35 123.4 30.0 2.5e-21 76.0 8.1 4.4 5 0 0 5 5 5 4 Mannosyltransferase (PIG-V)) HlyD_2 PF12700.2 CAM67151.1 - 0.1 11.7 2.5 0.14 11.2 1.7 1.3 1 0 0 1 1 1 0 HlyD family secretion protein Cupin_8 PF13621.1 CAM67151.1 - 0.13 11.7 0.2 0.15 11.5 0.2 1.1 1 0 0 1 1 1 0 Cupin-like domain Herpes_UL6 PF01763.11 CAM67151.1 - 0.14 10.2 4.7 0.17 10.0 3.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like GAS PF13851.1 CAM67151.1 - 0.16 11.1 10.4 0.26 10.4 7.2 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 CAM67151.1 - 0.59 9.8 13.3 0.079 12.7 6.4 1.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein OmpH PF03938.9 CAM67151.1 - 0.9 9.4 9.4 1.2 9.0 6.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FUSC PF04632.7 CAM67151.1 - 1.8 6.8 4.8 2.1 6.6 3.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family IncA PF04156.9 CAM67151.1 - 2.3 7.7 10.4 3.6 7.1 7.2 1.4 1 0 0 1 1 1 0 IncA protein Cwf_Cwc_15 PF04889.7 CAM67151.1 - 4 7.0 15.2 2.1 7.9 9.4 1.3 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Plasmid_RAQPRD PF09686.5 CAM67151.1 - 4.8 7.3 7.4 2.4 8.3 1.0 2.6 1 1 1 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) DUF972 PF06156.8 CAM67151.1 - 6.2 7.2 9.1 8.3 6.8 3.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) UDPGP PF01704.13 CAM67152.1 - 4.7e-89 298.7 0.0 7.4e-89 298.1 0.0 1.2 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Mito_carr PF00153.22 CAM67153.1 - 8e-20 70.3 5.2 3e-10 39.6 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein Phage_XkdX PF09693.5 CAM67153.1 - 0.34 10.4 2.2 13 5.4 0.1 3.2 3 0 0 3 3 3 0 Phage uncharacterised protein (Phage_XkdX) Robl_LC7 PF03259.12 CAM67154.1 - 4.5e-22 77.4 0.0 5.2e-22 77.2 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain IncA PF04156.9 CAM67155.1 - 0.002 17.7 19.5 0.0034 16.9 1.2 3.2 3 0 0 3 3 3 2 IncA protein Synaptobrevin PF00957.16 CAM67155.1 - 0.051 13.1 1.7 0.13 11.8 1.2 1.6 1 0 0 1 1 1 0 Synaptobrevin TAFH PF07531.9 CAM67155.1 - 0.11 12.1 1.0 2.1 8.0 0.1 3.2 2 1 1 3 3 3 0 NHR1 homology to TAF SlyX PF04102.7 CAM67155.1 - 3.2 8.1 16.9 0.075 13.4 1.8 4.2 4 0 0 4 4 4 0 SlyX DUF4131 PF13567.1 CAM67156.1 - 0.32 10.3 4.2 0.61 9.4 2.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) PhoD PF09423.5 CAM67157.1 - 5.9e-10 38.2 0.4 1.5e-08 33.7 0.3 2.3 1 1 0 1 1 1 1 PhoD-like phosphatase Hydantoinase_B PF02538.9 CAM67158.1 - 9.4e-172 571.9 0.0 2.9e-169 563.6 0.0 2.1 2 0 0 2 2 2 2 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 CAM67158.1 - 5.3e-87 291.5 0.4 1.3e-86 290.2 0.3 1.7 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 CAM67158.1 - 2.2e-50 170.5 0.6 1.1e-48 165.1 0.1 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region SynMuv_product PF06047.6 CAM67158.1 - 0.17 11.6 0.0 0.39 10.4 0.0 1.5 1 0 0 1 1 1 0 Ras-induced vulval development antagonist DUF3157 PF11355.3 CAM67159.1 - 0.12 11.6 0.1 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3157) DnaJ PF00226.26 CAM67159.1 - 0.23 11.2 0.0 0.52 10.0 0.0 1.5 1 0 0 1 1 1 0 DnaJ domain Peptidase_C2 PF00648.16 CAM67160.1 - 1e-11 44.3 0.0 6.4e-11 41.7 0.0 2.0 1 1 0 1 1 1 1 Calpain family cysteine protease SRP14 PF02290.10 CAM67160.1 - 0.056 13.3 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Signal recognition particle 14kD protein Vps16_C PF04840.7 CAM67161.1 - 4e-25 88.4 0.7 1.8e-12 46.8 0.0 2.5 2 1 1 3 3 3 2 Vps16, C-terminal region Vps16_N PF04841.8 CAM67161.1 - 6.9e-24 84.1 0.0 6.9e-23 80.8 0.0 2.4 1 1 0 1 1 1 1 Vps16, N-terminal region DUF169 PF02596.10 CAM67161.1 - 0.016 14.5 0.0 2.6 7.4 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised ArCR, COG2043 Pkinase PF00069.20 CAM67162.1 - 2.3e-71 239.9 0.0 2.7e-71 239.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM67162.1 - 2.3e-36 125.1 0.0 2.9e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM67162.1 - 5.3e-07 28.8 0.0 1.1e-06 27.7 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CAM67162.1 - 0.048 13.3 0.0 0.092 12.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 CAM67162.1 - 0.058 12.4 0.0 0.098 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CAM67162.1 - 0.13 11.5 0.1 0.32 10.2 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL PDEase_I PF00233.14 CAM67163.1 - 1.9e-67 227.4 1.0 3e-67 226.8 0.1 1.7 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Ank PF00023.25 CAM67164.1 - 7.4e-23 79.1 0.4 1.5e-09 37.1 0.1 3.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 CAM67164.1 - 5.5e-22 77.2 1.1 1.9e-08 34.2 0.0 4.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 CAM67164.1 - 3.5e-21 75.3 0.4 1.2e-13 51.2 0.0 2.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CAM67164.1 - 9.5e-18 62.5 0.7 8.7e-06 25.5 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 CAM67164.1 - 5.3e-16 58.6 1.5 4.9e-10 39.6 0.1 3.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Nol1_Nop2_Fmu PF01189.12 CAM67165.1 - 3.4e-24 85.7 0.0 2.2e-23 83.0 0.0 2.2 1 1 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 CAM67165.1 - 0.00027 20.9 0.0 0.00047 20.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 CAM67165.1 - 0.0061 16.5 0.0 0.023 14.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain zf-AN1 PF01428.11 CAM67166.1 - 2e-18 65.9 28.0 4.9e-10 39.1 6.7 2.6 2 0 0 2 2 2 2 AN1-like Zinc finger Transp_Tc5_C PF04236.10 CAM67166.1 - 0.0044 17.1 22.1 0.0067 16.6 1.7 2.9 3 0 0 3 3 3 2 Tc5 transposase C-terminal domain IBR PF01485.16 CAM67166.1 - 5.5 6.9 25.7 0.09 12.6 2.4 3.4 4 0 0 4 4 4 0 IBR domain Ras PF00071.17 CAM67167.1 - 8.3e-52 174.8 0.1 3.3e-51 172.8 0.0 1.7 1 1 0 1 1 1 1 Ras family Miro PF08477.8 CAM67167.1 - 4e-14 53.1 0.0 1.5e-13 51.2 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAM67167.1 - 1.7e-11 43.6 0.0 4.2e-10 39.1 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CAM67167.1 - 1.4e-05 24.3 0.0 1.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CAM67167.1 - 0.0028 17.6 0.0 0.0044 16.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CAM67167.1 - 0.0064 16.6 0.0 0.016 15.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 CAM67167.1 - 0.012 15.8 0.1 0.018 15.3 0.0 1.6 1 1 0 1 1 1 0 ABC transporter DUF258 PF03193.11 CAM67167.1 - 0.05 12.7 0.0 0.11 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF1327 PF07041.6 CAM67167.1 - 0.053 13.4 0.1 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1327) AAA_24 PF13479.1 CAM67167.1 - 0.086 12.4 0.0 0.096 12.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain MSG PF02349.10 CAM67168.1 - 0.073 13.0 2.3 0.56 10.2 1.6 2.5 1 0 0 1 1 1 0 Major surface glycoprotein zf-C3HC4_3 PF13920.1 CAM67169.1 - 7.3e-17 60.7 11.4 1.3e-16 59.9 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAM67169.1 - 4.9e-09 36.0 15.1 1.1e-08 34.9 10.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CAM67169.1 - 7.9e-06 25.6 12.9 1.6e-05 24.6 8.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CAM67169.1 - 0.0075 15.9 12.3 0.016 14.9 8.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zinc_ribbon_2 PF13240.1 CAM67169.1 - 0.0087 15.5 0.9 0.019 14.4 0.6 1.6 1 0 0 1 1 1 1 zinc-ribbon domain Pex14_N PF04695.8 CAM67169.1 - 0.091 12.8 7.6 0.23 11.5 4.9 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.4 CAM67169.1 - 0.13 10.4 14.9 0.16 10.1 10.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SOG2 PF10428.4 CAM67169.1 - 0.15 10.7 3.4 0.25 9.9 2.4 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein zf-P11 PF03854.9 CAM67169.1 - 0.26 10.7 10.2 0.62 9.5 7.1 1.7 1 1 0 1 1 1 0 P-11 zinc finger DUF605 PF04652.11 CAM67169.1 - 3.3 7.0 17.1 5.5 6.2 11.9 1.3 1 0 0 1 1 1 0 Vta1 like Prok-RING_4 PF14447.1 CAM67169.1 - 5.6 6.5 9.9 22 4.6 6.9 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 TPR_7 PF13176.1 CAM67170.1 - 0.076 12.8 0.2 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_4 PF07721.9 CAM67170.1 - 0.15 12.5 0.3 0.37 11.3 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Cmc1 PF08583.5 CAM67171.1 - 0.0059 16.3 2.6 0.013 15.2 1.8 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NPV_P10 PF05531.7 CAM67172.1 - 0.41 10.9 10.0 0.051 13.8 0.9 3.4 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Complex1_LYR PF05347.10 CAM67174.1 - 6.6e-10 38.6 1.8 6.6e-10 38.6 1.2 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CAM67174.1 - 2.7e-08 33.8 1.9 2.7e-08 33.8 1.3 2.0 2 0 0 2 2 2 1 Complex1_LYR-like ProRS-C_1 PF09180.6 CAM67175.1 - 3.2e-24 84.6 2.3 3.2e-24 84.6 1.6 2.0 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal tRNA_edit PF04073.10 CAM67175.1 - 1.4e-18 66.8 0.1 2.7e-18 65.9 0.1 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain tRNA-synt_2b PF00587.20 CAM67175.1 - 8.9e-16 57.9 0.0 2.1e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CAM67175.1 - 1.4e-15 56.9 0.0 5.5e-15 55.0 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain DEC-1_N PF04625.8 CAM67175.1 - 3.3 6.2 6.5 5.3 5.6 4.5 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region SET PF00856.23 CAM67176.1 - 1.7e-08 34.9 0.0 1.8e-07 31.5 0.0 2.2 1 1 0 1 1 1 1 SET domain PIH1 PF08190.7 CAM67177.1 - 2.8e-28 99.3 7.0 1.1e-19 71.1 0.0 5.1 4 1 2 6 6 6 3 pre-RNA processing PIH1/Nop17 MCRS_N PF13325.1 CAM67178.1 - 5.5e-05 22.7 0.0 9.6e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of micro-spherule protein Myb_DNA-binding PF00249.26 CAM67178.1 - 0.074 13.1 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Complex1_LYR PF05347.10 CAM67178.1 - 0.24 11.2 2.3 0.52 10.1 1.6 1.6 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Mito_carr PF00153.22 CAM67180.1 - 4.6e-36 122.4 4.6 4.5e-15 55.1 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein DmpG_comm PF07836.6 CAM67180.1 - 0.26 10.7 1.3 21 4.5 0.0 3.4 4 0 0 4 4 4 0 DmpG-like communication domain ProRS-C_1 PF09180.6 CAM67181.1 - 2.7e-24 84.8 2.3 2.7e-24 84.8 1.6 2.0 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal tRNA_edit PF04073.10 CAM67181.1 - 7e-22 77.5 0.1 1.4e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain HGTP_anticodon PF03129.15 CAM67181.1 - 1.4e-15 57.0 0.0 4.6e-15 55.3 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.20 CAM67181.1 - 1.9e-15 56.8 0.0 3.6e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Mito_carr PF00153.22 CAM67182.1 - 1.3e-34 117.7 6.6 4.8e-14 51.8 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein DmpG_comm PF07836.6 CAM67182.1 - 0.16 11.3 0.4 21 4.6 0.0 3.2 3 0 0 3 3 3 0 DmpG-like communication domain Acetyltransf_1 PF00583.19 CAM67183.1 - 2.6e-09 36.9 0.2 1.1e-05 25.4 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CAM67183.1 - 1.3e-05 25.2 0.0 0.0031 17.6 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CAM67183.1 - 0.0076 16.3 0.1 0.063 13.4 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Mucin PF01456.12 CAM67183.1 - 0.025 14.3 0.3 0.025 14.3 0.2 5.3 3 3 0 4 4 4 0 Mucin-like glycoprotein DUF3049 PF11250.3 CAM67183.1 - 0.45 10.3 3.6 3.8 7.3 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3049) Phytochelatin PF05023.9 CAM67184.1 - 0.0024 16.8 0.0 3.9 6.3 0.0 3.4 3 0 0 3 3 3 2 Phytochelatin synthase CTP_transf_2 PF01467.21 CAM67185.1 - 4e-11 43.2 0.0 6.7e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase CDP-OH_P_transf PF01066.16 CAM67185.1 - 4.2e-06 26.9 3.2 4.2e-06 26.9 2.2 3.7 2 2 0 2 2 2 1 CDP-alcohol phosphatidyltransferase FAD_syn PF06574.7 CAM67185.1 - 0.058 13.0 0.6 0.23 11.0 0.1 2.3 2 1 0 2 2 2 0 FAD synthetase zf-CCCH PF00642.19 CAM67186.1 - 0.00018 21.0 9.7 0.19 11.4 4.3 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH PF00642.19 CAM67187.1 - 0.001 18.7 10.2 0.016 14.9 1.4 2.7 2 1 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1150 PF06620.6 CAM67187.1 - 0.35 10.7 2.0 2.4 8.0 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1150) Reo_sigmaC PF04582.7 CAM67188.1 - 4.6 6.3 28.5 0.24 10.5 1.2 4.4 4 0 0 4 4 4 0 Reovirus sigma C capsid protein E1_dh PF00676.15 CAM67190.1 - 9.8e-102 339.7 0.4 1.1e-101 339.4 0.3 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 CAM67190.1 - 0.00075 18.5 0.6 0.0014 17.6 0.0 1.6 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase RRF PF01765.14 CAM67190.1 - 0.36 10.2 5.1 0.53 9.7 3.6 1.2 1 0 0 1 1 1 0 Ribosome recycling factor DUF4330 PF14221.1 CAM67191.1 - 0.15 11.8 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) Ribosomal_L34e PF01199.13 CAM67192.1 - 1.2e-27 95.9 3.9 1.2e-27 95.9 2.7 2.2 2 1 0 2 2 2 1 Ribosomal protein L34e RecA PF00154.16 CAM67192.1 - 0.032 13.3 2.2 0.04 12.9 1.6 1.1 1 0 0 1 1 1 0 recA bacterial DNA recombination protein PGM_PMM_III PF02880.11 CAM67192.1 - 0.25 11.3 1.2 0.39 10.7 0.3 1.8 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III NARP1 PF12569.3 CAM67192.1 - 0.52 9.0 8.9 0.57 8.8 6.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PUF PF00806.14 CAM67194.1 - 2e-45 149.7 0.6 1.1e-05 24.6 0.0 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DnaJ PF00226.26 CAM67195.1 - 1.3e-17 63.2 0.1 1.3e-17 63.2 0.1 2.0 2 0 0 2 2 2 1 DnaJ domain EF-hand_7 PF13499.1 CAM67196.1 - 5.8e-11 42.3 2.3 1.5e-07 31.3 0.5 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CAM67196.1 - 9.9e-09 34.3 1.1 9.9e-05 21.9 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 CAM67196.1 - 2.9e-08 32.4 3.1 0.0026 16.9 0.1 3.8 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 CAM67196.1 - 0.00067 19.2 5.3 0.58 9.8 0.0 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 CAM67196.1 - 0.0042 16.3 0.2 0.0042 16.3 0.1 3.2 4 0 0 4 4 4 1 EF hand DUF3648 PF12364.3 CAM67197.2 - 2.3e-56 189.7 3.0 6.4e-56 188.2 2.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3648) PAP_assoc PF03828.14 CAM67197.2 - 0.79 9.7 0.9 1.7 8.6 0.6 1.5 1 0 0 1 1 1 0 Cid1 family poly A polymerase WD40 PF00400.27 CAM67198.1 - 1.1e-06 28.2 2.9 0.0035 17.1 0.5 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat NADH-G_4Fe-4S_3 PF10588.4 CAM67200.1 - 7e-17 60.3 0.3 7e-17 60.3 0.2 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.1 CAM67200.1 - 9.6e-13 47.7 0.1 2.5e-12 46.4 0.1 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.22 CAM67200.1 - 8.7e-08 31.8 0.2 2.3e-07 30.4 0.1 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.1 CAM67200.1 - 0.26 11.7 6.4 0.14 12.6 2.3 2.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 CAM67200.1 - 2.2 8.5 7.4 0.84 9.9 2.1 2.5 3 0 0 3 3 3 0 4Fe-4S dicluster domain zf-C3HC4_3 PF13920.1 CAM67200.1 - 4 7.1 9.2 15 5.3 0.0 3.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Fer4_7 PF12838.2 CAM67200.1 - 4.8 7.6 11.6 1.3e+02 3.0 7.7 3.1 2 1 1 3 3 3 0 4Fe-4S dicluster domain DnaJ PF00226.26 CAM67201.1 - 5.9e-12 45.1 0.0 1e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.8 CAM67201.1 - 8.3e-06 25.2 3.7 2.2e-05 23.8 2.6 1.8 1 1 0 1 1 1 1 CSL zinc finger E1-E2_ATPase PF00122.15 CAM67203.2 - 2.9e-57 193.3 2.7 3.8e-57 192.9 1.9 1.1 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.21 CAM67203.2 - 7.6e-14 50.9 0.0 1.6e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.21 CAM67203.2 - 7.6e-05 23.2 0.0 0.00039 20.8 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CAM67203.2 - 0.037 13.9 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit WTF PF03303.8 CAM67203.2 - 0.078 12.3 4.6 0.12 11.7 3.2 1.2 1 0 0 1 1 1 0 WTF protein HAD PF12710.2 CAM67203.2 - 0.091 12.9 0.6 0.25 11.4 0.0 2.1 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF2207 PF09972.4 CAM67203.2 - 0.11 11.0 2.2 0.15 10.5 1.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) E1-E2_ATPase PF00122.15 CAM67204.1 - 2.3e-57 193.7 2.1 1.3e-56 191.1 1.9 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CAM67204.1 - 2.6e-24 86.8 0.0 1.8e-23 84.1 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CAM67204.1 - 1.5e-13 49.9 0.0 3.5e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CAM67204.1 - 2.4e-13 50.7 0.1 8e-13 48.9 0.1 2.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CAM67204.1 - 2.6e-05 23.9 0.0 0.00018 21.2 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CAM67204.1 - 0.075 13.0 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit WTF PF03303.8 CAM67204.1 - 0.57 9.5 6.8 0.29 10.5 3.1 1.6 2 0 0 2 2 2 0 WTF protein DUF2207 PF09972.4 CAM67204.1 - 8.1 4.8 7.8 0.46 8.9 1.7 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) E1-E2_ATPase PF00122.15 CAM67205.2 - 2.2e-57 193.7 2.1 1.3e-56 191.1 1.9 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CAM67205.2 - 2.6e-24 86.8 0.0 1.8e-23 84.1 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CAM67205.2 - 1.5e-13 49.9 0.0 3.5e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CAM67205.2 - 2.4e-13 50.6 0.1 8e-13 48.9 0.1 2.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CAM67205.2 - 2.7e-05 23.8 0.0 0.00018 21.2 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CAM67205.2 - 0.064 13.2 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit WTF PF03303.8 CAM67205.2 - 0.11 11.8 4.5 0.29 10.5 3.1 1.6 1 0 0 1 1 1 0 WTF protein DUF2207 PF09972.4 CAM67205.2 - 8.1 4.8 7.8 0.46 8.9 1.7 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Kinesin PF00225.18 CAM67206.2 - 1.7e-48 165.0 0.0 3e-48 164.2 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain AAA_22 PF13401.1 CAM67206.2 - 0.017 15.2 0.4 0.11 12.6 0.0 2.5 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 CAM67206.2 - 0.07 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.1 CAM67206.2 - 0.65 10.2 5.1 6.2 7.0 0.0 3.0 4 0 0 4 4 4 0 AAA domain UAA PF08449.6 CAM67207.1 - 6.8e-48 163.1 8.5 9.7e-48 162.6 5.9 1.2 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 CAM67207.1 - 3.4e-05 23.5 10.9 0.00011 21.9 1.9 2.6 2 1 0 2 2 2 2 Triose-phosphate Transporter family BTB PF00651.26 CAM67208.1 - 3.1e-05 23.9 0.0 0.00011 22.1 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain zf-C3HC4_3 PF13920.1 CAM67210.1 - 1.4e-14 53.4 13.7 1.9e-14 53.0 9.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAM67210.1 - 4.9e-07 29.6 17.3 7.2e-07 29.1 12.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CAM67210.1 - 0.0028 17.4 16.2 0.0041 16.9 11.2 1.3 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.1 CAM67210.1 - 0.083 12.4 9.8 0.17 11.4 6.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 IU_nuc_hydro PF01156.14 CAM67211.1 - 1.3e-96 323.5 1.9 1.4e-96 323.3 1.3 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Kinesin PF00225.18 CAM67213.1 - 1.1e-63 214.9 0.1 1.9e-63 214.1 0.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain Noc2 PF03715.8 CAM67214.1 - 2.8e-97 325.2 3.1 5e-97 324.3 2.1 1.4 1 0 0 1 1 1 1 Noc2p family Nop14 PF04147.7 CAM67214.1 - 0.0047 14.9 20.0 0.51 8.1 12.0 2.2 2 0 0 2 2 2 2 Nop14-like family Potyvirid-P3 PF13608.1 CAM67214.1 - 0.093 11.8 6.2 0.048 12.7 2.2 2.0 2 0 0 2 2 2 0 Protein P3 of Potyviral polyprotein DUF4375 PF14300.1 CAM67214.1 - 2.3 8.2 7.2 1.1 9.3 2.7 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4375) Got1 PF04178.7 CAM67215.1 - 5e-16 58.8 16.2 5.7e-16 58.6 11.2 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF872 PF05915.7 CAM67215.1 - 0.72 9.7 3.3 0.65 9.8 1.1 1.8 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) ATP1G1_PLM_MAT8 PF02038.11 CAM67215.1 - 5.3 6.1 6.3 1.1 8.3 0.1 2.8 2 1 1 3 3 3 0 ATP1G1/PLM/MAT8 family DUF1765 PF08578.5 CAM67217.1 - 0.13 12.3 0.0 3.9 7.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1765) HCMVantigenic_N PF12154.3 CAM67218.1 - 0.025 14.4 0.1 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 Glycoprotein B N-terminal antigenic domain of HCMV DnaJ PF00226.26 CAM67219.1 - 1.3e-13 50.4 0.3 1.1e-12 47.4 0.1 2.3 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.1 CAM67219.1 - 1e-06 28.2 11.4 0.015 14.9 0.1 4.1 4 1 1 5 5 5 4 TPR repeat TPR_2 PF07719.12 CAM67219.1 - 2e-05 24.1 8.0 0.11 12.4 0.1 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 CAM67219.1 - 0.0015 18.0 5.4 0.64 9.7 0.1 4.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 CAM67219.1 - 0.0017 18.2 17.9 0.84 9.6 0.0 4.9 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 CAM67219.1 - 0.034 13.9 1.0 6.4 6.8 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 CAM67219.1 - 0.83 10.4 23.5 0.79 10.4 3.0 5.5 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 CAM67219.1 - 2.1 8.2 12.5 1.4 8.8 0.1 4.0 3 2 1 4 4 4 0 Tetratricopeptide repeat GCS PF03074.11 CAM67220.1 - 1.1e-166 554.4 0.1 1.4e-166 554.1 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase zf-CCCH PF00642.19 CAM67222.1 - 3.7e-05 23.3 7.0 0.0019 17.8 0.7 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) U-box PF04564.10 CAM67222.1 - 0.0065 16.4 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 U-box domain SNARE PF05739.14 CAM67223.1 - 1.4e-09 37.4 3.5 3.5e-09 36.2 0.6 2.6 2 0 0 2 2 2 1 SNARE domain Syntaxin-6_N PF09177.6 CAM67223.1 - 0.015 15.6 2.8 0.03 14.7 0.6 2.5 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Syntaxin PF00804.20 CAM67223.1 - 0.084 13.0 14.0 0.16 12.1 0.4 2.6 2 1 0 2 2 2 0 Syntaxin Peptidase_S49_N PF08496.5 CAM67223.1 - 0.27 11.0 4.3 0.8 9.4 3.0 1.8 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Fib_alpha PF08702.5 CAM67223.1 - 9.5 6.3 11.3 2.4 8.2 3.3 2.6 2 2 0 2 2 2 0 Fibrinogen alpha/beta chain family Histone PF00125.19 CAM67225.2 - 4.8e-16 58.6 1.2 6.6e-16 58.2 0.8 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CAM67225.2 - 0.0041 17.1 0.3 0.0075 16.3 0.2 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DNA_photolyase PF00875.13 CAM67225.2 - 0.017 14.8 0.0 0.021 14.6 0.0 1.1 1 0 0 1 1 1 0 DNA photolyase Mito_carr PF00153.22 CAM67226.1 - 2.6e-67 222.5 3.5 2.3e-23 81.7 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein polyprenyl_synt PF00348.12 CAM67227.2 - 5.4e-37 127.0 0.0 7.5e-37 126.5 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase CrtC PF07143.6 CAM67227.2 - 1.1e-26 93.9 0.1 5.5e-25 88.3 0.0 2.0 2 0 0 2 2 2 2 Hydroxyneurosporene synthase (CrtC) FAM222A PF15258.1 CAM67227.2 - 0.25 10.4 0.0 0.38 9.9 0.0 1.1 1 0 0 1 1 1 0 Protein family of FAM222A Complex1_LYR PF05347.10 CAM67228.1 - 1.1e-07 31.4 0.6 1.6e-06 27.7 0.0 3.0 3 0 0 3 3 3 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CAM67228.1 - 1.6e-05 25.0 0.1 0.00023 21.3 0.0 2.8 2 1 0 2 2 2 1 Complex1_LYR-like GN3L_Grn1 PF08701.6 CAM67229.1 - 7.3e-05 22.5 13.1 0.00017 21.4 9.1 1.6 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase UVR PF02151.14 CAM67230.1 - 3.1e-09 36.0 15.0 7e-06 25.3 1.1 2.7 2 0 0 2 2 2 2 UvrB/uvrC motif HEAT_EZ PF13513.1 CAM67230.1 - 0.24 11.9 0.1 0.24 11.9 0.1 3.6 4 0 0 4 4 4 0 HEAT-like repeat zf-Di19 PF05605.7 CAM67230.1 - 0.61 10.2 22.5 0.044 13.9 3.2 2.8 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 CAM67230.1 - 5.9 7.3 10.5 15 6.0 1.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Kinesin PF00225.18 CAM67231.1 - 1.1e-102 343.2 0.0 1.8e-102 342.4 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain VHS PF00790.14 CAM67231.1 - 1.6e-06 27.8 0.2 7.4e-06 25.6 0.0 2.2 2 0 0 2 2 2 1 VHS domain TPR_MLP1_2 PF07926.7 CAM67231.1 - 0.81 9.4 19.1 4.4 7.0 7.2 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Dynamin_N PF00350.18 CAM67233.1 - 7.3e-18 64.9 0.0 2.1e-10 40.6 0.0 2.4 1 1 1 2 2 2 2 Dynamin family MMR_HSR1 PF01926.18 CAM67233.1 - 3e-07 30.4 0.0 7e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase U-box PF04564.10 CAM67235.1 - 0.0027 17.6 0.0 0.0087 15.9 0.0 1.9 1 0 0 1 1 1 1 U-box domain UCR_hinge PF02320.11 CAM67235.1 - 0.028 14.3 3.9 0.073 13.0 2.7 1.7 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein UPF0016 PF01169.14 CAM67236.1 - 6.8e-44 147.9 20.5 2.1e-23 82.2 2.9 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Abhydrolase_9_N PF15420.1 CAM67236.1 - 0.00046 19.9 1.4 0.00083 19.1 0.1 1.9 1 1 1 2 2 2 1 Alpha/beta-hydrolase family N-terminus Ion_trans PF00520.26 CAM67236.1 - 0.042 13.0 2.2 0.098 11.8 1.5 1.7 1 1 0 1 1 1 0 Ion transport protein ABC_transp_aux PF09822.4 CAM67237.2 - 5.8e-08 32.5 0.0 9.9e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 ABC-type uncharacterized transport system DUF1355 PF07090.6 CAM67237.2 - 0.15 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1355) WD40 PF00400.27 CAM67238.1 - 9.9e-11 41.0 0.7 1.3e-05 24.8 0.0 3.4 4 0 0 4 4 4 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 CAM67238.1 - 0.0041 15.9 0.0 0.012 14.4 0.0 1.7 2 0 0 2 2 2 1 Coatomer WD associated region DUF1143 PF06608.6 CAM67239.2 - 0.0017 18.3 0.4 1.6 8.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1143) Radical_SAM PF04055.16 CAM67240.1 - 6.5e-10 39.4 0.3 1.2e-09 38.5 0.2 1.5 1 1 0 1 1 1 1 Radical SAM superfamily Pkinase PF00069.20 CAM67241.1 - 9.9e-31 106.8 0.0 1e-16 60.8 0.0 4.1 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAM67241.1 - 1.9e-07 30.4 0.1 0.0067 15.5 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase RIO1 PF01163.17 CAM67241.1 - 0.019 14.2 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family WD40 PF00400.27 CAM67243.2 - 2.4e-16 58.9 0.2 0.0022 17.8 0.0 5.0 4 0 0 4 4 4 3 WD domain, G-beta repeat PDZ_2 PF13180.1 CAM67243.2 - 9.5e-06 25.4 0.0 2.1e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PQQ_3 PF13570.1 CAM67243.2 - 8.2 6.8 8.3 21 5.5 0.0 4.3 4 0 0 4 4 4 0 PQQ-like domain Ribosomal_S13_N PF08069.7 CAM67244.1 - 6.7e-25 86.7 2.0 6.7e-25 86.7 1.4 1.7 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 CAM67244.1 - 2.2e-21 75.3 0.3 3.4e-21 74.8 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 Synaptobrevin PF00957.16 CAM67245.1 - 5.4e-12 45.1 0.0 1e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 CAM67245.1 - 0.009 15.5 0.0 0.062 12.8 0.0 2.1 2 0 0 2 2 2 1 Regulated-SNARE-like domain UMP1 PF05348.6 CAM67246.1 - 5e-08 32.9 0.0 6.9e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 TFIIS_C PF01096.13 CAM67247.1 - 2.9e-19 68.3 2.6 2.9e-19 68.3 1.8 2.7 4 0 0 4 4 4 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 CAM67247.1 - 2.5e-05 23.8 0.9 5.8e-05 22.6 0.1 1.9 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Baculo_LEF5_C PF11792.3 CAM67247.1 - 0.0033 16.7 1.1 0.018 14.4 0.2 2.4 2 0 0 2 2 2 1 Baculoviridae late expression factor 5 C-terminal domain Zn_Tnp_IS1595 PF12760.2 CAM67247.1 - 0.013 15.2 3.8 0.22 11.3 0.1 2.7 2 1 0 2 2 2 0 Transposase zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 CAM67247.1 - 0.027 14.2 1.8 0.55 10.0 0.0 3.0 2 2 1 3 3 3 0 PhnA Zinc-Ribbon DUF2387 PF09526.5 CAM67247.1 - 0.079 12.8 2.1 1.9 8.4 0.3 2.5 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) DUF4379 PF14311.1 CAM67247.1 - 0.28 11.0 0.1 0.28 11.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4379) RRN7 PF11781.3 CAM67247.1 - 0.31 10.5 5.7 5.1 6.6 0.4 3.2 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 Elf1 PF05129.8 CAM67247.1 - 0.48 10.1 3.3 8.9 6.0 0.1 2.5 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like DUF2296 PF10058.4 CAM67247.1 - 0.84 9.4 3.9 4.9 6.9 0.1 3.1 3 0 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) Tmemb_55A PF09788.4 CAM67247.1 - 2.1 7.4 7.4 2.4 7.1 0.8 2.1 1 1 1 2 2 2 0 Transmembrane protein 55A Ank_4 PF13637.1 CAM67248.1 - 0.015 15.8 0.0 2.2 8.9 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) NAP PF00956.13 CAM67249.1 - 2.5e-62 210.1 0.5 2.5e-62 210.1 0.3 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Osteoregulin PF07175.6 CAM67249.1 - 0.03 14.1 0.1 0.078 12.7 0.1 1.8 1 1 0 1 1 1 0 Osteoregulin Daxx PF03344.10 CAM67249.1 - 0.083 11.3 3.5 0.13 10.7 2.5 1.2 1 0 0 1 1 1 0 Daxx Family Nucleoplasmin PF03066.10 CAM67249.1 - 0.18 11.2 10.6 2.7 7.5 3.5 2.7 2 0 0 2 2 2 0 Nucleoplasmin PBP1_TM PF14812.1 CAM67249.1 - 4.8 7.5 13.0 0.85 9.9 0.5 3.0 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Uso1_p115_C PF04871.8 CAM67250.2 - 0.044 13.7 0.4 0.079 12.8 0.3 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2360 PF10152.4 CAM67251.1 - 5.3e-55 185.7 0.0 8.4e-55 185.1 0.0 1.3 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) DUF605 PF04652.11 CAM67251.1 - 0.036 13.4 1.0 0.045 13.1 0.7 1.1 1 0 0 1 1 1 0 Vta1 like Proteasom_PSMB PF10508.4 CAM67251.1 - 0.098 10.9 0.4 0.12 10.5 0.3 1.1 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit Herpes_TK PF00693.13 CAM67252.1 - 0.069 12.3 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Thymidine kinase from herpesvirus Lipoprotein_20 PF13942.1 CAM67255.1 - 0.08 12.4 1.9 0.089 12.3 0.2 1.8 2 0 0 2 2 2 0 YfhG lipoprotein bZIP_1 PF00170.16 CAM67255.1 - 0.18 11.7 0.2 0.18 11.7 0.1 2.4 3 0 0 3 3 3 0 bZIP transcription factor LRR_4 PF12799.2 CAM67258.1 - 1.8e-07 30.5 0.0 0.11 12.1 0.0 3.6 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM67258.1 - 0.0063 16.2 0.2 0.63 9.8 0.0 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 CAM67258.1 - 0.21 11.7 0.5 36 4.9 0.0 3.6 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_7 PF13504.1 CAM67258.1 - 4.9 7.8 5.4 25 5.6 0.1 4.3 5 0 0 5 5 5 0 Leucine rich repeat Peptidase_M24 PF00557.19 CAM67259.1 - 1.1e-43 149.2 0.0 1.4e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 CAM67259.1 - 9.2e-06 25.4 4.6 2.3e-05 24.1 3.2 1.7 1 0 0 1 1 1 1 MYND finger IR1-M PF12185.3 CAM67259.1 - 1.1 9.0 3.8 3 7.6 2.6 1.7 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain DUF1042 PF06294.6 CAM67260.1 - 9.9e-05 21.9 0.0 0.00018 21.1 0.0 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1042) Prominin PF05478.6 CAM67261.1 - 0.79 7.1 28.5 0.0039 14.8 5.9 2.4 1 1 1 2 2 2 0 Prominin Prominin PF05478.6 CAM67262.1 - 0.77 7.2 28.3 0.0059 14.2 6.0 2.5 1 1 0 2 2 2 0 Prominin Pkinase PF00069.20 CAM67264.2 - 1.5e-42 145.5 0.0 1.7e-33 115.8 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CAM67264.2 - 1.2e-15 57.2 0.0 5.3e-15 55.1 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM67264.2 - 0.72 8.7 0.0 1.5 7.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like PDE6_gamma PF04868.7 CAM67264.2 - 0.74 9.6 4.3 12 5.7 0.3 2.8 2 0 0 2 2 2 0 Retinal cGMP phosphodiesterase, gamma subunit Cep57_CLD_2 PF14197.1 CAM67265.1 - 0.32 10.9 3.2 0.55 10.1 2.2 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 DAG1 PF05454.6 CAM67266.1 - 0.017 14.3 0.4 0.02 14.0 0.3 1.1 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Nuc_sug_transp PF04142.10 CAM67266.1 - 0.042 12.9 0.3 0.049 12.7 0.2 1.0 1 0 0 1 1 1 0 Nucleotide-sugar transporter Mid2 PF04478.7 CAM67266.1 - 0.11 11.8 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor CYTH PF01928.16 CAM67267.1 - 1.1e-13 51.3 0.0 9.5e-05 22.1 0.0 3.6 3 0 0 3 3 3 3 CYTH domain Histone PF00125.19 CAM67268.1 - 2.5e-23 81.9 0.4 4.2e-23 81.2 0.3 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CAM67268.1 - 3.2e-06 27.0 0.0 6.7e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CAM67268.1 - 0.013 15.2 0.1 0.024 14.3 0.1 1.5 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 CAM67268.1 - 0.032 13.5 1.6 0.035 13.3 1.1 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Gene66 PF02053.10 CAM67268.1 - 0.053 12.9 1.1 0.062 12.6 0.7 1.2 1 0 0 1 1 1 0 Gene 66 (IR5) protein CENP-S PF15630.1 CAM67268.1 - 0.098 12.8 0.1 0.2 11.8 0.1 1.4 1 0 0 1 1 1 0 Kinetochore component CENP-S ANF_receptor PF01094.23 CAM67269.1 - 6.4e-29 100.8 7.0 1.6e-20 73.1 2.1 3.5 3 1 0 3 3 3 3 Receptor family ligand binding region Surp PF01805.15 CAM67270.2 - 0.0023 17.5 0.0 0.0051 16.4 0.0 1.5 1 0 0 1 1 1 1 Surp module RE_XamI PF09572.5 CAM67270.2 - 0.024 14.0 0.0 0.051 13.0 0.0 1.5 1 0 0 1 1 1 0 XamI restriction endonuclease Methyltransf_23 PF13489.1 CAM67270.2 - 0.036 13.7 0.0 0.091 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Lysyl_oxidase PF01186.12 CAM67270.2 - 0.056 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Lysyl oxidase RNA_pol_A_bac PF01000.21 CAM67271.1 - 6.2e-20 71.4 0.0 1e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CAM67271.1 - 5.7e-10 38.1 0.0 7.7e-10 37.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_7 PF12838.2 CAM67271.1 - 0.0076 16.6 0.4 0.021 15.2 0.3 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 CAM67271.1 - 0.062 13.1 0.5 0.13 12.0 0.3 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 CAM67271.1 - 0.062 13.5 0.5 0.15 12.3 0.3 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Utp11 PF03998.8 CAM67272.1 - 0.0021 17.9 18.3 0.0046 16.8 1.8 2.0 1 1 1 2 2 2 2 Utp11 protein ATP-synt_ab_C PF00306.22 CAM67272.1 - 0.028 14.8 2.9 0.056 13.9 2.0 1.7 1 1 0 1 1 1 0 ATP synthase alpha/beta chain, C terminal domain DUF4407 PF14362.1 CAM67272.1 - 0.42 9.5 16.3 0.52 9.2 11.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NifQ PF04891.7 CAM67272.1 - 0.44 10.6 3.2 0.39 10.8 1.0 1.7 1 1 1 2 2 2 0 NifQ DUF2852 PF11014.3 CAM67272.1 - 1.5 8.8 7.5 0.08 12.8 0.9 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2852) FUSC PF04632.7 CAM67272.1 - 4.9 5.4 7.0 6.8 4.9 4.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Syntaxin PF00804.20 CAM67272.1 - 5.1 7.3 10.2 4.5 7.4 4.2 2.6 1 1 1 2 2 2 0 Syntaxin Kinesin PF00225.18 CAM67273.2 - 1.8e-93 312.9 0.0 1.7e-92 309.6 0.0 2.4 2 0 0 2 2 2 1 Kinesin motor domain Kinesin PF00225.18 CAM67274.2 - 9e-95 317.1 1.2 1.4e-76 257.4 0.2 4.2 3 0 0 3 3 3 3 Kinesin motor domain Ldh_1_N PF00056.18 CAM67275.1 - 1.4e-35 122.2 0.6 2.1e-35 121.6 0.4 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CAM67275.1 - 4e-30 104.8 0.0 5.5e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 CAM67275.1 - 0.0089 14.7 0.0 0.031 12.9 0.0 1.8 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 CAM67275.1 - 0.012 15.5 0.3 0.023 14.6 0.2 1.4 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.5 CAM67275.1 - 0.055 13.1 0.2 0.099 12.2 0.1 1.3 1 0 0 1 1 1 0 KR domain Baculo_PEP_C PF04513.7 CAM67276.1 - 9.1e-07 28.7 6.8 0.023 14.5 0.2 3.3 2 1 1 3 3 3 3 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 CAM67276.1 - 6.8e-05 21.6 6.5 0.019 13.6 0.7 2.2 2 0 0 2 2 2 2 Spc7 kinetochore protein DUF1664 PF07889.7 CAM67276.1 - 0.00029 20.6 10.0 0.013 15.2 0.5 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.7 CAM67276.1 - 0.003 16.8 5.3 0.13 11.3 0.8 2.2 1 1 1 2 2 2 2 Reovirus sigma C capsid protein DUF2353 PF09789.4 CAM67276.1 - 0.0053 16.0 0.3 0.0053 16.0 0.2 2.1 2 0 0 2 2 2 1 Uncharacterized coiled-coil protein (DUF2353) Mod_r PF07200.8 CAM67276.1 - 0.0059 16.5 8.9 1.3 8.9 0.0 2.7 2 1 1 3 3 3 2 Modifier of rudimentary (Mod(r)) protein ApoLp-III PF07464.6 CAM67276.1 - 0.007 16.3 1.6 0.007 16.3 1.1 2.8 1 1 2 3 3 3 1 Apolipophorin-III precursor (apoLp-III) Syntaxin_2 PF14523.1 CAM67276.1 - 0.0075 16.2 4.5 0.1 12.6 0.0 3.3 2 1 1 3 3 2 1 Syntaxin-like protein Bacillus_HBL PF05791.6 CAM67276.1 - 0.0091 15.3 4.2 0.31 10.3 0.4 2.9 2 1 1 3 3 3 1 Bacillus haemolytic enterotoxin (HBL) DUF2730 PF10805.3 CAM67276.1 - 0.0098 15.6 6.9 0.012 15.2 0.1 3.0 3 1 0 3 3 3 1 Protein of unknown function (DUF2730) LXG PF04740.7 CAM67276.1 - 0.014 15.2 9.1 0.047 13.4 0.1 3.1 1 1 2 3 3 3 0 LXG domain of WXG superfamily Snapin_Pallidin PF14712.1 CAM67276.1 - 0.014 15.6 9.0 0.074 13.3 0.7 3.6 3 1 1 4 4 3 0 Snapin/Pallidin MutS_III PF05192.13 CAM67276.1 - 0.036 13.8 5.6 0.072 12.8 3.8 1.6 1 1 0 1 1 1 0 MutS domain III KBP_C PF12309.3 CAM67276.1 - 0.053 12.4 1.7 0.06 12.3 0.1 1.7 2 0 0 2 2 2 0 KIF-1 binding protein C terminal Prefoldin_2 PF01920.15 CAM67276.1 - 0.056 13.2 8.3 3.3 7.5 0.1 3.7 3 1 0 3 3 3 0 Prefoldin subunit LOH1CR12 PF10158.4 CAM67276.1 - 0.06 13.1 4.2 0.24 11.2 0.1 2.8 2 1 1 3 3 3 0 Tumour suppressor protein DUF948 PF06103.6 CAM67276.1 - 0.085 12.7 2.3 33 4.4 0.2 3.7 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF892 PF05974.7 CAM67276.1 - 0.09 12.5 8.8 2.1 8.1 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF892) MitMem_reg PF13012.1 CAM67276.1 - 0.09 12.8 4.8 12 6.0 0.1 3.5 2 1 2 4 4 4 0 Maintenance of mitochondrial structure and function DUF1409 PF07197.7 CAM67276.1 - 0.13 12.3 2.6 0.65 10.0 1.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) Seryl_tRNA_N PF02403.17 CAM67276.1 - 0.14 12.2 10.0 6.4 6.8 0.2 3.4 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain COG2 PF06148.6 CAM67276.1 - 0.16 11.8 15.2 1.2 8.9 1.6 4.0 1 1 3 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 LIF_OSM PF01291.12 CAM67276.1 - 0.16 11.8 1.4 2 8.2 0.1 2.6 3 0 0 3 3 2 0 LIF / OSM family DASH_Dad3 PF08656.5 CAM67276.1 - 0.18 11.5 5.2 1.8 8.2 0.1 3.3 2 1 0 2 2 2 0 DASH complex subunit Dad3 DUF724 PF05266.9 CAM67276.1 - 0.22 11.1 6.7 3.3 7.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF4208 PF13907.1 CAM67276.1 - 0.27 11.4 2.4 4.9 7.4 0.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4208) Baculo_p24 PF05073.7 CAM67276.1 - 0.29 10.6 3.3 5 6.6 0.1 2.3 2 1 0 2 2 2 0 Baculovirus P24 capsid protein AAA_13 PF13166.1 CAM67276.1 - 0.4 9.0 4.6 1.2 7.4 2.9 1.7 1 1 0 1 1 1 0 AAA domain GAS PF13851.1 CAM67276.1 - 0.45 9.6 8.9 3.7 6.6 2.4 3.0 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4559 PF15112.1 CAM67276.1 - 0.46 9.5 4.3 0.2 10.8 0.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) IncA PF04156.9 CAM67276.1 - 0.5 9.9 17.7 0.12 11.9 1.0 2.9 1 1 2 3 3 3 0 IncA protein Nsp1_C PF05064.8 CAM67276.1 - 0.5 10.0 7.0 3.1 7.4 0.3 3.2 2 1 2 4 4 4 0 Nsp1-like C-terminal region MAT1 PF06391.8 CAM67276.1 - 0.55 9.7 8.2 0.15 11.5 2.5 2.0 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Fmp27_WPPW PF10359.4 CAM67276.1 - 0.55 8.5 10.6 2.5 6.4 3.0 2.1 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Laminin_II PF06009.7 CAM67276.1 - 0.59 9.8 12.1 1.2 8.9 0.1 3.4 1 1 2 4 4 4 0 Laminin Domain II DUF552 PF04472.7 CAM67276.1 - 0.63 9.9 4.5 1.1 9.2 0.5 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF552) BLOC1_2 PF10046.4 CAM67276.1 - 0.88 9.7 9.1 23 5.2 0.4 3.8 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 V_ATPase_I PF01496.14 CAM67276.1 - 1.1 6.9 8.7 3.3 5.4 2.7 2.2 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family Tropomyosin_1 PF12718.2 CAM67276.1 - 1.2 8.9 16.9 4.8 7.0 6.5 3.1 1 1 0 2 2 2 0 Tropomyosin like TMP_2 PF06791.8 CAM67276.1 - 1.4 8.5 5.3 1.3 8.5 1.0 2.5 1 1 2 3 3 3 0 Prophage tail length tape measure protein DUF972 PF06156.8 CAM67276.1 - 1.4 9.3 10.2 4.7 7.5 0.2 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF972) ALIX_LYPXL_bnd PF13949.1 CAM67276.1 - 1.5 7.6 16.8 0.12 11.2 4.0 2.7 1 1 0 2 2 2 0 ALIX V-shaped domain binding to HIV DUF4200 PF13863.1 CAM67276.1 - 1.7 8.6 12.7 12 5.8 0.1 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) DUF2721 PF11026.3 CAM67276.1 - 1.8 8.2 6.5 0.98 9.0 0.1 2.8 2 1 1 3 3 2 0 Protein of unknown function (DUF2721) FliD_C PF07195.7 CAM67276.1 - 1.8 7.8 5.9 9.8 5.3 0.2 2.9 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 C-terminus Fib_alpha PF08702.5 CAM67276.1 - 1.9 8.5 8.2 6.6 6.8 0.3 3.0 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DASH_Dam1 PF08653.5 CAM67276.1 - 2 8.2 4.4 24 4.7 0.0 3.6 3 2 0 3 3 3 0 DASH complex subunit Dam1 DUF4239 PF14023.1 CAM67276.1 - 2 7.7 6.8 4.5 6.5 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) Pex19 PF04614.7 CAM67276.1 - 2.2 7.8 10.8 1.8 8.1 4.0 2.1 1 1 1 2 2 2 0 Pex19 protein family T2SF PF00482.18 CAM67276.1 - 4.3 7.2 10.3 11 5.9 0.1 3.7 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein F NPV_P10 PF05531.7 CAM67276.1 - 4.9 7.4 11.0 28 5.0 0.2 4.3 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Pilt PF15453.1 CAM67276.1 - 5.1 6.6 9.5 1.2 8.7 4.3 1.4 2 0 0 2 2 1 0 Protein incorporated later into Tight Junctions DUF4446 PF14584.1 CAM67276.1 - 5.1 6.9 11.1 2.8 7.7 0.4 3.3 1 1 0 2 2 2 0 Protein of unknown function (DUF4446) CENP-H PF05837.7 CAM67276.1 - 5.7 7.1 13.0 1.4 9.1 2.5 3.0 2 2 1 3 3 3 0 Centromere protein H (CENP-H) Methyltransf_12 PF08242.7 CAM67277.1 - 1.2e-10 41.6 0.0 2.3e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CAM67277.1 - 1.3e-09 38.4 0.0 2.9e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAM67277.1 - 8.1e-08 32.1 0.0 1.8e-07 30.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAM67277.1 - 9e-06 25.3 0.0 1.8e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAM67277.1 - 0.00023 21.4 0.0 0.00044 20.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CAM67277.1 - 0.0014 17.7 0.0 0.0022 17.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.10 CAM67277.1 - 0.0028 17.2 0.0 0.0053 16.4 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_18 PF12847.2 CAM67277.1 - 0.11 13.1 0.0 0.26 11.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain EAP30 PF04157.11 CAM67278.1 - 7.9e-41 139.6 0.2 1.1e-40 139.1 0.2 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 CAM67278.1 - 1.1e-23 82.8 0.0 1.8e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Ribosomal_S25 PF03297.10 CAM67278.1 - 0.011 15.7 0.1 0.031 14.3 0.0 1.8 2 0 0 2 2 2 0 S25 ribosomal protein WWbp PF10349.4 CAM67278.1 - 0.013 16.3 0.4 0.025 15.4 0.3 1.4 1 0 0 1 1 1 0 WW-domain ligand protein PhnJ PF06007.6 CAM67278.1 - 0.041 12.6 0.0 0.061 12.0 0.0 1.2 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnJ IRS PF02174.12 CAM67278.1 - 0.048 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 PTB domain (IRS-1 type) Pox_G7 PF05503.7 CAM67279.1 - 0.097 11.2 0.2 0.14 10.6 0.2 1.1 1 0 0 1 1 1 0 Poxvirus G7-like Mem_trans PF03547.13 CAM67280.1 - 1.5e-31 109.0 2.2 6.3e-31 107.0 1.5 1.9 1 1 0 1 1 1 1 Membrane transport protein V-SNARE_C PF12352.3 CAM67281.1 - 2e-09 37.3 4.3 3e-09 36.8 1.7 2.2 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 CAM67281.1 - 8.6e-06 25.3 0.0 4.2e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 Sec20 IncA PF04156.9 CAM67281.1 - 0.00061 19.4 0.1 0.00061 19.4 0.1 1.6 2 0 0 2 2 2 1 IncA protein Poty_PP PF08440.5 CAM67281.1 - 0.017 14.1 0.4 0.16 11.0 0.0 2.0 2 0 0 2 2 2 0 Potyviridae polyprotein MCPsignal PF00015.16 CAM67281.1 - 0.049 13.1 1.3 0.12 11.9 0.3 1.9 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Rabaptin PF03528.10 CAM67281.1 - 0.049 13.5 0.8 0.1 12.4 0.5 1.6 1 0 0 1 1 1 0 Rabaptin Prefoldin PF02996.12 CAM67281.1 - 0.075 12.6 2.7 3.5 7.2 0.3 2.5 2 1 0 2 2 2 0 Prefoldin subunit SLT_2 PF13406.1 CAM67281.1 - 0.26 10.1 3.6 5.1 5.9 0.0 2.4 2 1 0 2 2 2 0 Transglycosylase SLT domain RmuC PF02646.11 CAM67281.1 - 0.31 9.8 3.1 0.32 9.8 0.6 2.0 2 1 0 2 2 2 0 RmuC family SRP72 PF08492.7 CAM67283.1 - 4.4e-08 33.3 0.1 4.4e-08 33.3 0.1 2.2 2 0 0 2 2 1 1 SRP72 RNA-binding domain TPR_19 PF14559.1 CAM67283.1 - 1.5e-07 31.6 38.4 5.4e-05 23.4 0.3 8.0 6 2 2 8 8 8 3 Tetratricopeptide repeat Apc3 PF12895.2 CAM67283.1 - 1.5e-07 31.4 20.6 7.2e-06 26.0 4.3 5.5 4 2 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 CAM67283.1 - 3.7e-05 23.9 43.2 0.13 12.9 1.0 9.4 5 3 3 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 CAM67283.1 - 4.4e-05 23.3 7.7 0.26 11.5 0.0 5.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 CAM67283.1 - 7.7e-05 23.2 43.1 0.0043 17.6 1.1 7.6 5 2 3 8 8 7 4 Tetratricopeptide repeat TPR_12 PF13424.1 CAM67283.1 - 0.00019 21.2 26.1 0.038 13.9 0.1 5.4 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 CAM67283.1 - 0.0031 17.1 23.6 0.14 11.8 0.4 5.5 5 1 1 7 7 7 2 TPR repeat PPR_3 PF13812.1 CAM67283.1 - 0.016 15.4 5.5 78 3.9 0.0 5.3 5 0 0 5 5 4 0 Pentatricopeptide repeat domain TPR_7 PF13176.1 CAM67283.1 - 0.017 14.8 12.2 1.7 8.6 1.3 5.7 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 CAM67283.1 - 0.086 12.7 28.3 1.8 8.6 3.1 7.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 CAM67283.1 - 0.19 12.2 24.9 6.8 7.3 0.9 7.3 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 CAM67283.1 - 0.31 10.9 9.3 7.3 6.6 0.9 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 CAM67283.1 - 0.65 9.8 0.0 0.1 12.4 2.1 5.7 5 1 2 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 CAM67283.1 - 1.3 8.7 14.6 14 5.4 1.7 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 CAM67283.1 - 5 7.8 40.0 3.8 8.2 0.2 8.9 9 0 0 9 9 7 0 Tetratricopeptide repeat ABC_tran PF00005.22 CAM67284.1 - 3.4e-43 147.2 0.0 1.1e-20 74.3 0.0 2.9 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 CAM67284.1 - 6.1e-23 82.2 0.1 1.7e-08 34.7 0.1 4.2 3 1 0 3 3 3 3 AAA domain ABC_tran_2 PF12848.2 CAM67284.1 - 1.9e-22 78.8 4.7 2.2e-21 75.4 1.4 2.5 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 CAM67284.1 - 2.4e-11 43.2 2.4 0.0017 17.6 0.0 4.7 4 1 1 5 5 5 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 CAM67284.1 - 3.3e-09 37.5 0.1 0.0018 19.0 0.0 3.5 4 0 0 4 4 2 2 AAA domain AAA_28 PF13521.1 CAM67284.1 - 5.3e-07 29.7 0.0 0.015 15.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 CAM67284.1 - 1.1e-06 28.9 0.0 0.0068 16.5 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 CAM67284.1 - 1.7e-06 28.3 0.1 0.018 15.3 0.0 3.3 4 0 0 4 4 2 2 AAA domain RNA_helicase PF00910.17 CAM67284.1 - 2.7e-06 27.5 0.1 0.016 15.3 0.0 3.4 4 0 0 4 4 3 1 RNA helicase AAA_29 PF13555.1 CAM67284.1 - 3.3e-06 26.5 0.1 0.096 12.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_33 PF13671.1 CAM67284.1 - 3.6e-06 26.9 0.1 0.1 12.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 CAM67284.1 - 4.7e-06 27.0 6.9 0.1 12.9 0.0 3.5 4 0 0 4 4 3 2 AAA domain AAA_16 PF13191.1 CAM67284.1 - 8.3e-06 25.9 2.0 0.03 14.3 0.0 3.4 2 2 1 3 3 3 2 AAA ATPase domain NACHT PF05729.7 CAM67284.1 - 9.3e-06 25.3 0.1 0.031 13.9 0.0 2.9 3 0 0 3 3 3 2 NACHT domain AAA_14 PF13173.1 CAM67284.1 - 2.4e-05 24.2 0.0 0.78 9.6 0.0 3.5 4 0 0 4 4 3 2 AAA domain AAA_13 PF13166.1 CAM67284.1 - 3.1e-05 22.6 0.2 0.67 8.3 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.9 CAM67284.1 - 4.1e-05 23.3 0.0 0.04 13.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CAM67284.1 - 5.8e-05 23.2 0.0 0.097 12.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 CAM67284.1 - 6.6e-05 22.1 0.0 0.31 10.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 CAM67284.1 - 7e-05 22.3 0.0 0.34 10.2 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.1 CAM67284.1 - 0.00011 21.4 0.3 4.7 6.1 0.1 4.4 3 1 2 5 5 5 0 AAA ATPase domain MobB PF03205.9 CAM67284.1 - 0.00016 21.3 0.1 0.09 12.4 0.0 2.9 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 CAM67284.1 - 0.00017 22.1 0.0 0.25 11.8 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_10 PF12846.2 CAM67284.1 - 0.00019 20.9 0.5 0.5 9.7 0.0 3.6 4 0 0 4 4 4 1 AAA-like domain UPF0079 PF02367.12 CAM67284.1 - 0.0004 20.0 0.2 0.01 15.4 0.0 3.0 2 1 1 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 CAM67284.1 - 0.0007 19.1 0.0 0.26 10.7 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 CAM67284.1 - 0.00096 18.9 0.0 0.28 10.8 0.0 2.7 3 0 0 3 3 2 1 Archaeal ATPase SbcCD_C PF13558.1 CAM67284.1 - 0.0017 18.2 0.0 0.38 10.7 0.0 3.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 CAM67284.1 - 0.0017 18.2 0.0 1.8 8.5 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_19 PF13245.1 CAM67284.1 - 0.0029 17.2 0.0 0.17 11.6 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 CAM67284.1 - 0.0036 16.4 0.0 0.084 11.9 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin Mg_chelatase PF01078.16 CAM67284.1 - 0.012 14.8 0.0 4.8 6.2 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ArgK PF03308.11 CAM67284.1 - 0.019 13.7 0.5 0.66 8.6 0.0 2.5 3 0 0 3 3 3 0 ArgK protein Rad17 PF03215.10 CAM67284.1 - 0.02 13.5 0.1 0.9 8.1 0.0 2.3 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein ATP-synt_ab PF00006.20 CAM67284.1 - 0.022 14.2 0.0 3.4 7.1 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.10 CAM67284.1 - 0.029 14.0 0.0 0.77 9.4 0.0 2.4 2 0 0 2 2 2 0 NTPase SRP54 PF00448.17 CAM67284.1 - 0.033 13.6 0.1 0.66 9.3 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain cobW PF02492.14 CAM67284.1 - 0.033 13.6 0.1 2.4 7.5 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.12 CAM67284.1 - 0.036 13.4 0.0 2.5 7.4 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein NB-ARC PF00931.17 CAM67284.1 - 0.036 12.9 0.0 6.1 5.6 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain Sigma54_activ_2 PF14532.1 CAM67284.1 - 0.041 13.9 0.0 1.1 9.2 0.0 2.8 3 0 0 3 3 2 0 Sigma-54 interaction domain RuvB_N PF05496.7 CAM67284.1 - 0.049 12.6 0.1 0.34 9.9 0.0 2.0 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus VirE PF05272.6 CAM67284.1 - 0.052 13.0 0.0 14 5.0 0.0 3.0 3 0 0 3 3 3 0 Virulence-associated protein E AAA_24 PF13479.1 CAM67284.1 - 0.069 12.7 2.4 1.2 8.6 0.0 3.0 4 0 0 4 4 2 0 AAA domain AAA_PrkA PF08298.6 CAM67284.1 - 0.093 11.4 0.0 2.4 6.7 0.0 2.5 3 0 0 3 3 3 0 PrkA AAA domain Vps53_N PF04100.7 CAM67285.1 - 5.4e-66 222.9 9.7 7.4e-66 222.4 6.7 1.1 1 0 0 1 1 1 1 Vps53-like, N-terminal COG2 PF06148.6 CAM67285.1 - 0.0017 18.2 1.0 0.0044 16.8 0.7 1.8 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF2450 PF10475.4 CAM67285.1 - 0.047 12.5 6.9 0.18 10.7 2.6 2.5 3 0 0 3 3 3 0 Protein of unknown function N-terminal domain (DUF2450) Reo_sigmaC PF04582.7 CAM67285.1 - 0.064 12.4 1.9 0.12 11.5 1.3 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein TMV_coat PF00721.16 CAM67285.1 - 0.28 11.1 3.5 0.33 10.8 0.2 2.6 3 0 0 3 3 3 0 Virus coat protein (TMV like) IncA PF04156.9 CAM67285.1 - 2.3 7.7 12.8 0.042 13.4 3.3 2.1 2 0 0 2 2 2 0 IncA protein Kinesin PF00225.18 CAM67286.2 - 1.9e-91 306.2 0.1 9.4e-91 303.9 0.0 2.2 3 0 0 3 3 3 1 Kinesin motor domain Atg8 PF02991.11 CAM67287.2 - 3e-10 39.9 0.0 3.9e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like ExbD PF02472.11 CAM67287.2 - 0.011 15.6 0.0 0.013 15.5 0.0 1.1 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR BMC PF00936.14 CAM67287.2 - 0.21 11.2 4.9 2 8.1 3.4 2.5 1 1 1 2 2 2 0 BMC domain Atg8 PF02991.11 CAM67288.2 - 3e-10 39.9 0.0 3.9e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like ExbD PF02472.11 CAM67288.2 - 0.012 15.6 0.0 0.013 15.4 0.0 1.1 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR BMC PF00936.14 CAM67288.2 - 0.29 10.8 5.3 2.6 7.8 3.5 2.4 1 1 1 2 2 2 0 BMC domain Atg8 PF02991.11 CAM67289.1 - 6.5e-10 38.9 0.0 8.4e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like ExbD PF02472.11 CAM67289.1 - 0.02 14.9 0.0 0.023 14.6 0.0 1.1 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR BMC PF00936.14 CAM67289.1 - 0.37 10.5 4.4 3 7.6 3.2 2.3 1 1 1 2 2 2 0 BMC domain AMP-binding PF00501.23 CAM67292.1 - 6.5e-87 291.6 1.0 7.8e-87 291.3 0.7 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CAM67292.1 - 8.8e-10 39.4 0.1 2.9e-09 37.7 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain BT1 PF03092.11 CAM67293.1 - 6.3e-168 558.9 12.9 7.3e-168 558.7 8.9 1.0 1 0 0 1 1 1 1 BT1 family PdxJ PF03740.8 CAM67293.1 - 0.057 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthesis protein PdxJ CAP_GLY PF01302.20 CAM67295.1 - 3e-18 65.2 0.1 4.5e-18 64.6 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain DUF1878 PF08963.5 CAM67295.1 - 0.79 9.9 13.3 0.7 10.1 1.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1878) Dynein_light PF01221.13 CAM67297.1 - 2.7e-30 104.1 0.2 3.1e-30 103.9 0.1 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 FKBP_C PF00254.23 CAM67298.1 - 2.2e-12 46.8 0.0 3.3e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FYVE PF01363.16 CAM67299.1 - 3e-13 49.4 10.6 1.8e-12 46.9 7.3 2.2 1 1 0 1 1 1 1 FYVE zinc finger zf-DHHC PF01529.15 CAM67299.1 - 1.8 7.9 6.1 0.47 9.8 1.8 1.8 2 0 0 2 2 2 0 DHHC palmitoyltransferase AMP-binding PF00501.23 CAM67301.1 - 1.3e-76 257.7 0.1 1.6e-76 257.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CAM67301.1 - 8.5e-10 39.4 0.0 3.1e-09 37.6 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain WD40 PF00400.27 CAM67302.1 - 7.3e-21 73.2 3.3 1.2e-06 28.1 0.3 7.7 8 0 0 8 8 8 5 WD domain, G-beta repeat eIF2A PF08662.6 CAM67302.1 - 0.014 15.0 0.0 0.22 11.2 0.0 2.4 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A PseudoU_synth_1 PF01416.15 CAM67303.1 - 3.9e-13 49.7 0.1 3.5e-10 40.2 0.0 3.5 3 0 0 3 3 3 1 tRNA pseudouridine synthase Cir_N PF10197.4 CAM67304.1 - 0.036 14.1 7.7 0.036 14.1 5.4 3.3 3 1 1 4 4 4 0 N-terminal domain of CBF1 interacting co-repressor CIR DUF4252 PF14060.1 CAM67304.1 - 0.12 11.9 0.6 9.1 5.8 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4252) Mnd1 PF03962.10 CAM67304.1 - 0.53 9.9 12.2 0.18 11.4 1.1 2.3 2 0 0 2 2 2 0 Mnd1 family B5 PF03484.10 CAM67305.1 - 2e-18 65.9 0.0 7.8e-16 57.6 0.1 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain B3_4 PF03483.12 CAM67305.1 - 5.8e-18 64.9 0.0 1e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain Prominin PF05478.6 CAM67307.1 - 1.3 6.4 1.6 2.4 5.5 1.1 1.4 1 0 0 1 1 1 0 Prominin DAGK_cat PF00781.19 CAM67308.2 - 8.5e-12 44.6 0.2 5e-09 35.6 0.2 2.8 2 1 0 2 2 2 2 Diacylglycerol kinase catalytic domain Mito_carr PF00153.22 CAM67312.1 - 1e-55 185.4 6.9 7.5e-19 67.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PCI PF01399.22 CAM67313.1 - 1.5e-08 34.9 0.0 4.8e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 PCI domain DUF1843 PF08898.5 CAM67313.1 - 0.0012 18.8 0.1 0.086 12.8 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1843) Ank_2 PF12796.2 CAM67314.2 - 6.6e-29 100.0 26.2 1.8e-08 34.5 0.5 11.9 8 5 5 13 13 13 10 Ankyrin repeats (3 copies) Ank PF00023.25 CAM67314.2 - 7.5e-21 72.8 38.3 0.00015 21.3 0.1 15.0 16 0 0 16 16 16 7 Ankyrin repeat Ank_3 PF13606.1 CAM67314.2 - 4.2e-17 60.5 33.4 0.018 15.2 0.0 16.0 16 0 0 16 16 16 4 Ankyrin repeat Ank_4 PF13637.1 CAM67314.2 - 6e-10 39.3 21.5 0.2 12.1 0.0 11.9 13 1 1 14 14 14 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CAM67314.2 - 2.2e-08 34.0 38.4 0.035 14.3 0.2 13.6 13 2 2 16 16 16 2 Ankyrin repeats (many copies) MMR_HSR1_C PF08438.5 CAM67318.1 - 0.027 14.7 0.0 0.11 12.7 0.0 2.1 1 1 0 1 1 1 0 GTPase of unknown function C-terminal DUF2011 PF09428.5 CAM67318.1 - 0.13 12.0 14.2 0.4 10.5 7.3 2.5 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF2011) RRN3 PF05327.6 CAM67318.1 - 2.8 5.9 6.7 0.24 9.4 0.5 1.9 1 1 1 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 DUF1675 PF07897.6 CAM67318.1 - 5.6 6.7 17.6 0.2 11.5 6.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) V_ATPase_I PF01496.14 CAM67318.1 - 9.7 3.8 6.8 13 3.4 4.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lzipper-MIP1 PF14389.1 CAM67319.1 - 0.092 12.8 6.3 3.6 7.7 0.0 3.5 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 CHCH PF06747.8 CAM67321.1 - 5.3e-07 29.3 1.7 8.5e-07 28.7 1.2 1.4 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 CAM67321.1 - 0.0018 17.9 1.6 0.004 16.9 1.1 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.8 CAM67321.1 - 0.0075 16.2 2.3 0.054 13.5 0.6 2.2 1 1 1 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) DUF1903 PF08991.5 CAM67321.1 - 0.024 14.7 0.2 0.033 14.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1903) COX6B PF02297.12 CAM67321.1 - 0.042 13.8 0.9 0.069 13.1 0.6 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 CAM67321.1 - 0.11 12.5 1.7 0.24 11.4 1.2 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Actin PF00022.14 CAM67322.1 - 3.2e-76 256.2 0.0 4e-76 255.9 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CAM67322.1 - 0.11 11.1 0.0 4.3 5.8 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein Fcf1 PF04900.7 CAM67323.1 - 1.2e-35 121.6 1.9 1.2e-35 121.6 1.3 1.6 2 0 0 2 2 2 1 Fcf1 NPFF PF15085.1 CAM67323.1 - 0.036 14.3 0.2 0.061 13.6 0.1 1.3 1 0 0 1 1 1 0 Neuropeptide FF Apc3 PF12895.2 CAM67324.1 - 0.011 15.8 2.7 0.023 14.8 1.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 CAM67324.1 - 0.025 14.9 1.1 0.053 13.9 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Thioredoxin PF00085.15 CAM67324.1 - 0.048 13.3 0.1 0.12 12.0 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin NMD3 PF04981.8 CAM67324.1 - 0.1 11.6 0.1 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 NMD3 family LEA_3 PF03242.8 CAM67325.1 - 1.8 8.8 5.6 1.2 9.4 0.4 2.8 2 1 1 3 3 3 0 Late embryogenesis abundant protein Pex2_Pex12 PF04757.9 CAM67327.1 - 5.2e-38 130.7 0.1 7.7e-38 130.1 0.1 1.3 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 CAM67327.1 - 0.0022 17.9 4.6 0.0037 17.2 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CAM67327.1 - 0.012 15.4 3.6 0.022 14.6 2.5 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.1 CAM67327.1 - 0.1 12.3 5.2 0.3 10.8 3.7 1.7 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Surp PF01805.15 CAM67329.1 - 1e-08 34.6 2.3 1e-08 34.6 1.6 2.0 2 1 0 2 2 2 1 Surp module Band_7 PF01145.20 CAM67330.1 - 2.2e-27 96.1 0.2 9.4e-27 94.0 0.0 1.8 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 CAM67330.1 - 0.0048 16.4 0.3 0.011 15.2 0.0 1.7 2 0 0 2 2 2 1 SPFH domain-Band 7 family V_ATPase_I PF01496.14 CAM67330.1 - 0.024 12.5 0.7 0.026 12.4 0.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Band_7 PF01145.20 CAM67331.1 - 4.1e-23 82.1 0.0 5.8e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Pkinase PF00069.20 CAM67332.1 - 1.7e-05 24.1 0.0 6.1e-05 22.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM67332.1 - 0.016 14.2 0.0 0.26 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase SH3_4 PF06347.8 CAM67333.1 - 0.14 11.7 1.1 0.25 10.8 0.0 2.0 2 0 0 2 2 2 0 Bacterial SH3 domain Calsequestrin PF01216.12 CAM67333.1 - 0.14 10.8 0.1 0.2 10.3 0.1 1.1 1 0 0 1 1 1 0 Calsequestrin MBOAT PF03062.14 CAM67347.1 - 2.9e-28 98.9 26.4 7.1e-24 84.5 6.7 3.0 2 1 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family PDZ_2 PF13180.1 CAM67348.1 - 0.024 14.5 0.0 0.084 12.7 0.0 1.9 2 0 0 2 2 2 0 PDZ domain PDZ PF00595.19 CAM67348.1 - 0.062 13.4 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) DUF641 PF04859.7 CAM67348.1 - 0.092 12.5 3.5 0.39 10.4 0.1 3.0 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) SlyX PF04102.7 CAM67348.1 - 0.5 10.7 4.3 4.5 7.7 0.1 3.1 3 0 0 3 3 3 0 SlyX TrkH PF02386.11 CAM67350.1 - 0.039 12.5 0.1 0.047 12.2 0.1 1.1 1 0 0 1 1 1 0 Cation transport protein DUF898 PF05987.8 CAM67350.1 - 0.053 12.4 1.7 0.053 12.4 1.2 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF4064 PF13273.1 CAM67350.1 - 0.44 10.6 2.7 0.93 9.6 1.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) TMEM154 PF15102.1 CAM67350.1 - 0.47 10.1 3.3 0.15 11.7 0.2 1.6 1 1 1 2 2 2 0 TMEM154 protein family Sar8_2 PF03058.9 CAM67350.1 - 0.77 10.1 2.6 1.4 9.3 1.7 1.6 1 1 0 1 1 1 0 Sar8.2 family FixP_N PF14715.1 CAM67350.1 - 0.95 8.8 8.7 1.7 8.0 6.0 1.4 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP SecG PF03840.9 CAM67350.1 - 1.6 8.5 9.5 6.4 6.5 6.6 1.9 1 1 0 1 1 1 0 Preprotein translocase SecG subunit OppC_N PF12911.2 CAM67350.1 - 2.2 7.6 6.8 1.7 8.0 0.4 2.4 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C BatA PF07584.6 CAM67350.1 - 5 7.4 7.6 14 5.9 4.2 2.1 1 1 1 2 2 2 0 Aerotolerance regulator N-terminal PAP2 PF01569.16 CAM67351.1 - 1.5e-19 69.9 2.6 1.5e-19 69.9 1.8 2.1 2 1 0 2 2 2 1 PAP2 superfamily Mtp PF03821.11 CAM67351.1 - 0.024 14.0 6.8 0.033 13.5 1.8 2.1 2 0 0 2 2 2 0 Golgi 4-transmembrane spanning transporter DUF3154 PF11351.3 CAM67351.1 - 0.16 11.7 1.1 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3154) RDD PF06271.7 CAM67351.1 - 0.82 9.5 7.9 0.45 10.3 2.2 2.2 2 0 0 2 2 2 0 RDD family DUF4131 PF13567.1 CAM67351.1 - 1.3 8.4 10.0 1 8.7 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF3671 PF12420.3 CAM67351.1 - 3.2 7.7 4.7 5.2 7.1 0.9 2.4 3 0 0 3 3 3 0 Protein of unknown function Cation_efflux PF01545.16 CAM67352.1 - 2.4e-31 108.8 10.3 6e-30 104.2 5.0 2.7 1 1 0 2 2 2 1 Cation efflux family TBP PF00352.16 CAM67353.1 - 1.2e-32 111.1 0.1 4.7e-18 64.3 0.0 2.6 2 1 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) TPR_17 PF13431.1 CAM67354.1 - 1.3e-08 34.3 0.1 0.0046 17.0 0.0 4.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 CAM67354.1 - 3.5e-08 32.7 1.6 0.00098 18.6 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 CAM67354.1 - 6.2e-08 31.9 6.8 0.0028 17.4 0.0 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 CAM67354.1 - 4.3e-07 29.4 1.9 0.7 9.5 0.1 4.1 2 2 3 5 5 4 3 TPR repeat TPR_8 PF13181.1 CAM67354.1 - 1.9e-05 24.0 1.0 0.0026 17.4 0.0 4.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 CAM67354.1 - 2.2e-05 24.2 1.0 0.00092 19.0 0.1 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CAM67354.1 - 6.6e-05 23.1 0.0 0.78 10.5 0.0 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 CAM67354.1 - 0.00026 21.2 1.2 0.28 11.7 0.1 3.2 3 0 0 3 3 2 2 Tetratricopeptide repeat Sel1 PF08238.7 CAM67354.1 - 0.00047 20.7 1.8 0.8 10.4 0.1 3.5 4 0 0 4 4 3 2 Sel1 repeat TPR_16 PF13432.1 CAM67354.1 - 0.00097 19.7 0.3 2.1 9.1 0.0 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_21 PF09976.4 CAM67354.1 - 0.021 14.7 0.1 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 CAM67354.1 - 0.022 14.5 0.1 0.12 12.2 0.0 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat PAP_assoc PF03828.14 CAM67355.1 - 8e-15 54.5 0.1 2e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase Peptidase_C1 PF00112.18 CAM67356.1 - 1.1e-69 234.6 1.5 1.5e-69 234.2 1.1 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 CAM67356.1 - 2.7e-07 30.7 0.3 2.7e-07 30.7 0.2 2.0 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 CAM67356.1 - 3.4e-06 25.8 0.4 0.0014 17.2 0.0 2.5 3 0 0 3 3 3 2 Peptidase C1-like family PIH1 PF08190.7 CAM67357.1 - 1.5e-17 64.0 0.1 5.5e-16 58.9 0.1 2.0 1 1 0 1 1 1 1 pre-RNA processing PIH1/Nop17 Pkinase PF00069.20 CAM67358.1 - 3.9e-67 226.1 0.0 4.6e-67 225.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM67358.1 - 1.6e-33 115.9 0.0 2.2e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM67358.1 - 7.4e-07 28.4 0.0 1.2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CAM67358.1 - 0.0018 18.0 1.1 0.0024 17.6 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CAM67358.1 - 0.027 13.5 0.5 0.059 12.4 0.3 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NAD_binding_1 PF00175.16 CAM67359.1 - 1e-11 45.3 0.0 2e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Oxidored-like PF09791.4 CAM67359.1 - 2.7e-11 42.7 1.3 5.7e-11 41.6 0.9 1.5 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal FAD_binding_1 PF00667.15 CAM67359.1 - 1e-07 31.6 0.0 2.7e-05 23.7 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain COX6B PF02297.12 CAM67360.1 - 0.066 13.2 2.4 0.15 12.0 1.6 1.7 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb Pkinase PF00069.20 CAM67361.1 - 6.7e-40 136.8 0.0 2.1e-26 92.6 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAM67361.1 - 1.6e-16 60.1 0.0 4e-14 52.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase IF4E PF01652.13 CAM67362.1 - 1.6e-43 148.1 0.2 2.1e-43 147.6 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E TPT PF03151.11 CAM67364.1 - 3.4e-25 88.4 10.9 3.4e-25 88.4 7.6 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 CAM67364.1 - 0.0003 20.8 10.8 0.0003 20.8 7.5 3.0 1 1 2 3 3 3 2 EamA-like transporter family UAA PF08449.6 CAM67364.1 - 0.0013 17.7 26.6 0.0024 16.8 18.4 1.4 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.1 CAM67364.1 - 0.28 11.4 24.4 0.048 13.8 4.8 3.2 2 1 2 4 4 4 0 Multidrug resistance efflux transporter DUF4131 PF13567.1 CAM67364.1 - 1.1 8.6 10.1 2.5 7.4 0.2 3.2 1 1 1 3 3 3 0 Domain of unknown function (DUF4131) FKBP_C PF00254.23 CAM67365.1 - 1.2e-30 105.3 0.0 7.6e-30 102.7 0.0 2.2 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_11 PF13414.1 CAM67365.1 - 6.8e-14 51.2 0.1 4.3e-08 32.6 0.0 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 CAM67365.1 - 1.4e-10 40.2 0.1 0.00046 19.8 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 CAM67365.1 - 1.7e-09 36.9 0.1 0.011 15.3 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 CAM67365.1 - 2.2e-08 34.5 1.6 0.0035 17.9 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CAM67365.1 - 4.8e-07 29.6 0.2 0.0013 18.6 0.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CAM67365.1 - 2.3e-06 27.7 1.9 0.0011 19.3 0.1 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CAM67365.1 - 2.6e-06 27.6 0.7 5.3e-05 23.4 0.2 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 CAM67365.1 - 0.0002 21.4 0.1 0.00042 20.4 0.0 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 CAM67365.1 - 0.00028 20.8 0.3 0.045 13.9 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CAM67365.1 - 0.00035 20.3 0.0 0.0018 18.1 0.0 2.1 1 1 1 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.1 CAM67365.1 - 0.001 18.6 0.1 0.1 12.4 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 CAM67365.1 - 0.0021 17.6 0.0 1.7 8.5 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 CAM67365.1 - 0.0033 17.3 0.2 2.3 8.2 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 CAM67365.1 - 0.044 14.2 0.6 0.47 11.0 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat IF3_N PF05198.11 CAM67366.1 - 0.0024 17.7 0.2 0.014 15.3 0.1 2.1 1 1 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain Carn_acyltransf PF00755.15 CAM67367.1 - 2.3e-125 419.0 0.0 1.7e-91 307.1 0.0 2.1 1 1 1 2 2 2 2 Choline/Carnitine o-acyltransferase WD40 PF00400.27 CAM67368.1 - 3e-14 52.2 1.9 4.2e-06 26.4 0.0 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat IMPDH PF00478.20 CAM67369.1 - 5e-131 436.7 3.1 5.8e-131 436.5 2.2 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 CAM67369.1 - 7.9e-14 51.1 0.1 1.4e-05 24.7 0.0 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 CAM67369.1 - 1.1e-09 37.5 0.3 1.1e-09 37.5 0.2 1.6 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 CAM67369.1 - 9.3e-07 28.2 2.3 0.013 14.6 0.7 2.5 3 0 0 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.16 CAM67369.1 - 0.027 13.7 0.2 0.4 9.9 0.0 2.3 1 1 1 2 2 2 0 Histidine biosynthesis protein ELMO_CED12 PF04727.8 CAM67370.1 - 1e-29 103.2 0.0 1.4e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family Transketolase_C PF02780.15 CAM67370.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Transketolase, C-terminal domain Peptidase_M41 PF01434.13 CAM67372.1 - 6e-45 153.3 0.4 1.2e-44 152.3 0.3 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CAM67372.1 - 7.7e-41 139.3 0.1 1.5e-39 135.2 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CAM67372.1 - 0.00014 22.0 0.6 0.0015 18.7 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CAM67372.1 - 0.00065 19.4 2.6 0.0018 18.0 0.1 2.8 3 0 0 3 3 3 1 Part of AAA domain AAA_5 PF07728.9 CAM67372.1 - 0.0012 18.5 0.4 0.02 14.6 0.3 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CAM67372.1 - 0.0029 17.0 0.2 0.0029 17.0 0.1 2.6 2 1 1 3 3 3 1 AAA domain AAA_17 PF13207.1 CAM67372.1 - 0.0029 18.4 0.0 0.0077 17.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CAM67372.1 - 0.0043 17.0 9.6 0.0077 16.2 0.1 3.9 1 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 CAM67372.1 - 0.0053 15.8 0.0 0.013 14.5 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus GRA6 PF05084.8 CAM67372.1 - 0.0058 16.1 0.1 0.011 15.2 0.1 1.4 1 0 0 1 1 1 1 Granule antigen protein (GRA6) IstB_IS21 PF01695.12 CAM67372.1 - 0.0095 15.3 0.1 0.023 14.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 CAM67372.1 - 0.015 14.0 0.0 0.03 13.0 0.0 1.5 1 0 0 1 1 1 0 TIP49 C-terminus Peptidase_M50B PF13398.1 CAM67372.1 - 0.018 14.4 0.0 0.043 13.2 0.0 1.6 1 0 0 1 1 1 0 Peptidase M50B-like AAA_14 PF13173.1 CAM67372.1 - 0.03 14.2 0.0 0.063 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 CAM67372.1 - 0.04 12.8 0.0 0.067 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF637 PF04830.8 CAM67372.1 - 0.043 13.4 0.5 0.64 9.6 0.0 2.7 3 0 0 3 3 3 0 Possible hemagglutinin (DUF637) Sigma54_activ_2 PF14532.1 CAM67372.1 - 0.049 13.6 0.4 4.6 7.2 0.0 2.7 2 1 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.7 CAM67372.1 - 0.092 12.3 0.1 0.39 10.3 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_2 PF07724.9 CAM67372.1 - 0.11 12.3 0.1 0.82 9.5 0.1 2.4 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) NTPase_1 PF03266.10 CAM67372.1 - 0.14 11.8 0.5 0.61 9.7 0.1 2.1 1 1 1 2 2 2 0 NTPase KaiC PF06745.8 CAM67372.1 - 0.17 11.0 0.1 0.51 9.4 0.1 1.8 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.1 CAM67372.1 - 0.17 12.2 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain SRP19 PF01922.12 CAM67373.1 - 1.6e-28 99.1 0.1 3.2e-28 98.1 0.1 1.5 1 1 0 1 1 1 1 SRP19 protein COMPASS-Shg1 PF05205.7 CAM67373.1 - 0.034 14.4 0.0 0.057 13.7 0.0 1.3 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 Pkinase PF00069.20 CAM67374.1 - 2.3e-18 66.2 0.0 2.9e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM67374.1 - 7.2e-06 25.2 0.0 2e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase BTB_2 PF02214.17 CAM67375.1 - 6.2e-13 48.7 0.0 1.7e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain NeA_P2 PF12312.3 CAM67375.1 - 0.097 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein Atg8 PF02991.11 CAM67376.1 - 1.7e-38 130.7 0.0 2e-38 130.5 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 CAM67376.1 - 9.1e-08 32.1 0.0 1.2e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 WD40 PF00400.27 CAM67379.1 - 4.3e-18 64.4 12.7 1.5e-06 27.8 0.6 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat Gmad1 PF10647.4 CAM67379.1 - 0.0081 15.5 0.0 0.016 14.6 0.0 1.6 1 1 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain PQQ_2 PF13360.1 CAM67379.1 - 0.014 14.8 0.1 1.1 8.6 0.0 2.6 1 1 1 2 2 2 0 PQQ-like domain Nup160 PF11715.3 CAM67379.1 - 0.041 12.0 4.9 0.14 10.2 0.4 2.2 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Hira PF07569.6 CAM67379.1 - 0.058 12.6 0.9 7.1 5.7 0.1 2.9 1 1 2 3 3 3 0 TUP1-like enhancer of split DOT1 PF08123.8 CAM67380.1 - 4.8e-19 68.4 0.0 6.6e-19 68.0 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 CAM67380.1 - 1.2e-07 32.2 0.0 4.6e-07 30.4 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CAM67380.1 - 5.5e-06 26.4 0.0 7.9e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAM67380.1 - 2.1e-05 24.7 0.0 3.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAM67380.1 - 2.4e-05 23.9 0.0 3.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CAM67380.1 - 0.00085 19.7 0.0 0.0021 18.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAM67380.1 - 0.0027 17.4 0.0 0.0036 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CAM67380.1 - 0.01 14.9 0.0 0.016 14.3 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 CAM67380.1 - 0.035 14.5 0.0 0.063 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 CAM67380.1 - 0.087 12.5 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Peripla_BP_3 PF13377.1 CAM67380.1 - 0.099 12.6 0.1 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein-like domain AdoMet_MTase PF07757.8 CAM67380.1 - 0.11 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase PHO4 PF01384.15 CAM67381.1 - 1.2e-104 349.4 19.6 1.8e-104 348.9 13.6 1.2 1 0 0 1 1 1 1 Phosphate transporter family ASF1_hist_chap PF04729.8 CAM67383.1 - 6e-52 175.3 0.0 6.6e-52 175.2 0.0 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone BRCA-2_OB1 PF09103.5 CAM67384.1 - 5.4e-34 116.4 0.0 9.7e-34 115.5 0.0 1.4 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA2 PF00634.13 CAM67384.1 - 4.1e-08 32.3 0.0 5.3e-05 22.4 0.0 2.5 2 0 0 2 2 2 2 BRCA2 repeat zf-RanBP PF00641.13 CAM67384.1 - 0.024 13.7 2.6 0.067 12.3 1.8 1.7 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Hydrophobin_2 PF06766.6 CAM67385.1 - 0.17 11.5 0.9 2.6 7.7 0.1 2.2 2 0 0 2 2 2 0 Fungal hydrophobin BK_channel_a PF03493.13 CAM67387.1 - 1.8e-24 85.6 0.0 4.5e-23 81.1 0.0 2.6 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.11 CAM67387.1 - 2.3e-12 46.4 6.3 2.3e-12 46.4 4.4 2.5 2 0 0 2 2 2 1 Ion channel NB-ARC PF00931.17 CAM67390.1 - 1.1e-05 24.4 0.0 0.0081 15.0 0.0 2.2 1 1 1 2 2 2 2 NB-ARC domain AAA_16 PF13191.1 CAM67390.1 - 5.7e-05 23.1 0.1 0.00029 20.8 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 CAM67390.1 - 0.0074 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 CAM67390.1 - 0.019 15.1 0.0 0.039 14.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 CAM67390.1 - 0.024 14.3 0.0 0.61 9.7 0.0 2.2 1 1 1 2 2 2 0 Archaeal ATPase DUF258 PF03193.11 CAM67390.1 - 0.027 13.6 0.0 0.065 12.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 NACHT PF05729.7 CAM67390.1 - 0.035 13.7 0.0 0.14 11.8 0.0 2.0 1 1 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 CAM67390.1 - 0.11 12.6 0.0 0.3 11.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase MORN PF02493.15 CAM67391.1 - 8.3e-14 50.4 10.3 1.5e-06 27.5 0.0 7.4 7 1 0 7 7 7 4 MORN repeat AAA_22 PF13401.1 CAM67393.2 - 0.092 12.8 0.0 0.37 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF1736 PF08409.6 CAM67394.1 - 2.7e-23 81.3 0.3 7.3e-23 79.9 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_11 PF13414.1 CAM67394.1 - 0.24 11.0 3.6 1.8 8.2 0.0 3.2 2 1 1 3 3 3 0 TPR repeat DUF1427 PF07235.6 CAM67394.1 - 0.34 11.0 2.7 16 5.6 1.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1427) AAA_13 PF13166.1 CAM67395.2 - 0.0068 14.9 4.9 0.014 13.9 3.4 1.4 1 0 0 1 1 1 1 AAA domain DUF4201 PF13870.1 CAM67395.2 - 0.0096 15.3 2.3 0.0096 15.3 1.6 2.1 1 1 0 2 2 2 1 Domain of unknown function (DUF4201) DUF812 PF05667.6 CAM67395.2 - 0.054 11.9 11.4 0.08 11.4 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF3450 PF11932.3 CAM67395.2 - 0.15 11.2 12.2 0.16 11.2 7.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Ada3 PF10198.4 CAM67395.2 - 0.92 9.2 7.5 0.42 10.3 3.0 2.1 2 0 0 2 2 2 0 Histone acetyltransferases subunit 3 TMF_TATA_bd PF12325.3 CAM67395.2 - 1.3 8.7 18.6 0.31 10.7 3.5 3.5 2 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.4 CAM67395.2 - 1.5 8.6 19.5 15 5.4 8.2 3.3 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LRR_6 PF13516.1 CAM67396.1 - 0.014 15.4 0.0 24 5.4 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich repeat PHY PF00360.15 CAM67396.1 - 0.064 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Phytochrome region MCPsignal PF00015.16 CAM67398.1 - 0.028 13.9 2.9 0.29 10.6 0.5 2.0 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain ALIX_LYPXL_bnd PF13949.1 CAM67398.1 - 0.058 12.3 0.1 0.09 11.7 0.1 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Kelch_3 PF13415.1 CAM67400.1 - 7.6e-28 95.9 13.1 8.5e-07 28.9 0.0 7.0 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_1 PF01344.20 CAM67400.1 - 3.4e-25 87.3 6.9 1.4e-07 30.9 0.1 6.2 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 CAM67400.1 - 6e-24 83.1 3.4 8.6e-05 22.5 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.1 CAM67400.1 - 1.6e-21 75.7 11.3 3.3e-06 26.9 0.0 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.1 CAM67400.1 - 5.1e-21 74.1 6.1 3.1e-05 23.6 0.0 6.1 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.10 CAM67400.1 - 9.5e-12 44.1 22.5 0.01 15.5 0.7 7.2 6 3 0 6 6 6 5 Kelch motif PQQ_3 PF13570.1 CAM67400.1 - 7.5 6.9 6.3 20 5.6 0.0 4.1 4 1 1 5 5 5 0 PQQ-like domain DUF4516 PF14990.1 CAM67402.1 - 0.02 14.4 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) RseC_MucC PF04246.7 CAM67403.1 - 0.091 12.3 0.4 2.8 7.5 0.0 2.6 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC DS PF01916.12 CAM67404.2 - 1.4e-75 254.1 0.0 1.9e-75 253.7 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Peptidase_S49_N PF08496.5 CAM67404.2 - 0.11 12.2 0.1 3.5 7.4 0.1 2.1 1 1 1 2 2 2 0 Peptidase family S49 N-terminal AAA_5 PF07728.9 CAM67405.2 - 3e-124 409.3 0.0 3e-23 82.0 0.0 8.7 8 0 0 8 8 8 8 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CAM67405.2 - 9.8e-27 93.1 0.0 0.0016 18.0 0.0 8.3 8 0 0 8 8 8 4 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CAM67405.2 - 1.6e-23 83.2 0.1 0.0016 18.5 0.0 8.1 7 0 0 7 7 7 6 AAA domain AAA PF00004.24 CAM67405.2 - 3e-21 75.9 0.1 0.0015 18.7 0.0 7.4 6 1 0 6 6 6 4 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CAM67405.2 - 1.3e-18 67.6 26.8 0.00031 20.7 0.1 10.6 10 1 0 10 10 8 4 AAA ATPase domain AAA_14 PF13173.1 CAM67405.2 - 1e-16 61.0 0.0 0.00038 20.3 0.0 6.6 6 1 0 6 6 5 3 AAA domain Sigma54_activ_2 PF14532.1 CAM67405.2 - 5e-16 59.0 1.2 0.00012 22.0 0.0 7.2 7 0 0 7 7 6 3 Sigma-54 interaction domain Sigma54_activat PF00158.21 CAM67405.2 - 1.2e-15 57.3 0.0 0.011 15.2 0.0 6.6 6 0 0 6 6 6 3 Sigma-54 interaction domain AAA_17 PF13207.1 CAM67405.2 - 1.7e-15 57.9 0.4 0.071 13.9 0.0 7.6 7 0 0 7 7 6 3 AAA domain AAA_29 PF13555.1 CAM67405.2 - 3e-10 39.4 0.8 3 7.4 0.0 6.7 6 0 0 6 6 6 1 P-loop containing region of AAA domain T2SE PF00437.15 CAM67405.2 - 5.1e-10 38.7 1.5 0.062 12.1 0.0 6.2 6 0 0 6 6 6 2 Type II/IV secretion system protein IstB_IS21 PF01695.12 CAM67405.2 - 1.2e-09 37.8 0.7 0.15 11.4 0.0 4.5 5 0 0 5 5 4 3 IstB-like ATP binding protein AAA_18 PF13238.1 CAM67405.2 - 1.3e-09 38.3 3.9 0.16 12.2 0.0 7.5 7 0 0 7 7 7 2 AAA domain ABC_tran PF00005.22 CAM67405.2 - 3e-09 37.2 12.8 0.36 11.1 0.0 7.3 7 0 0 7 7 6 3 ABC transporter UPF0079 PF02367.12 CAM67405.2 - 5.1e-09 35.8 3.8 0.071 12.7 0.0 6.3 6 0 0 6 6 6 1 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 CAM67405.2 - 6.7e-09 35.3 12.9 0.33 10.7 0.1 7.8 8 0 0 8 8 7 3 Part of AAA domain DUF258 PF03193.11 CAM67405.2 - 1.2e-08 34.2 1.1 0.33 10.1 0.0 5.4 5 0 0 5 5 5 2 Protein of unknown function, DUF258 RNA_helicase PF00910.17 CAM67405.2 - 1e-07 32.0 0.6 0.35 11.0 0.0 6.3 7 0 0 7 7 6 1 RNA helicase DUF815 PF05673.8 CAM67405.2 - 1.5e-07 30.6 4.5 0.17 10.7 0.0 5.0 6 0 0 6 6 4 2 Protein of unknown function (DUF815) NACHT PF05729.7 CAM67405.2 - 1.4e-05 24.8 2.1 0.96 9.0 0.0 5.7 6 0 0 6 6 6 1 NACHT domain RuvB_N PF05496.7 CAM67405.2 - 7.6e-05 21.8 0.3 0.7 8.8 0.0 4.6 5 0 0 5 5 5 1 Holliday junction DNA helicase ruvB N-terminus Rad17 PF03215.10 CAM67405.2 - 0.00056 18.7 0.2 14 4.1 0.0 4.7 5 0 0 5 5 5 0 Rad17 cell cycle checkpoint protein NTPase_1 PF03266.10 CAM67405.2 - 0.00095 18.9 1.1 1.7 8.3 0.0 4.1 4 0 0 4 4 4 1 NTPase Miro PF08477.8 CAM67405.2 - 0.0013 19.1 0.2 22 5.5 0.0 4.6 4 0 0 4 4 4 0 Miro-like protein KaiC PF06745.8 CAM67405.2 - 0.0081 15.3 0.3 20 4.2 0.0 4.5 5 0 0 5 5 5 0 KaiC ArgK PF03308.11 CAM67405.2 - 0.015 14.0 1.6 1.5 7.5 0.0 3.4 3 0 0 3 3 3 0 ArgK protein Arch_ATPase PF01637.13 CAM67405.2 - 0.033 13.8 0.0 15 5.1 0.0 4.1 4 0 0 4 4 4 0 Archaeal ATPase PduV-EutP PF10662.4 CAM67405.2 - 0.038 13.4 1.3 41 3.6 0.0 4.8 7 0 0 7 7 5 0 Ethanolamine utilisation - propanediol utilisation DNA_pol3_delta2 PF13177.1 CAM67405.2 - 0.064 12.9 0.0 12 5.5 0.0 3.6 3 0 0 3 3 3 0 DNA polymerase III, delta subunit AAA_6 PF12774.2 CAM67405.2 - 0.065 12.7 0.0 33 3.9 0.0 4.0 4 0 0 4 4 4 0 Hydrolytic ATP binding site of dynein motor region D1 PhoH PF02562.11 CAM67405.2 - 0.11 11.7 7.5 5.4 6.1 0.0 4.6 6 0 0 6 6 4 0 PhoH-like protein TIP49 PF06068.8 CAM67405.2 - 0.12 11.0 1.5 11 4.5 0.0 3.9 5 0 0 5 5 5 0 TIP49 C-terminus DUF87 PF01935.12 CAM67405.2 - 0.26 11.0 1.7 1.5 8.5 0.0 3.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 CAM67405.2 - 0.7 9.8 0.0 1.3e+02 2.5 0.0 3.6 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_21 PF13304.1 CAM67405.2 - 1.4 8.8 0.6 30 4.4 0.0 3.3 5 0 0 5 5 2 0 AAA domain Enkurin PF13864.1 CAM67407.1 - 2e-26 92.0 6.0 3.3e-26 91.3 4.2 1.4 1 0 0 1 1 1 1 Calmodulin-binding BCDHK_Adom3 PF10436.4 CAM67408.1 - 5.6e-33 113.7 0.1 9e-33 113.1 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CAM67408.1 - 3.4e-14 52.5 0.0 3.2e-13 49.3 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CAM67408.1 - 4.1e-05 23.2 0.0 7.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ZZ PF00569.12 CAM67409.1 - 2.4e-06 26.9 9.5 2.4e-06 26.9 6.6 2.8 2 0 0 2 2 2 1 Zinc finger, ZZ type LRR_6 PF13516.1 CAM67410.1 - 1.3e-06 27.8 0.2 0.26 11.4 0.0 4.8 5 0 0 5 5 5 2 Leucine Rich repeat LRR_7 PF13504.1 CAM67410.1 - 0.0064 16.4 0.8 1.2e+02 3.6 0.0 5.0 5 0 0 5 5 5 0 Leucine rich repeat LRR_4 PF12799.2 CAM67410.1 - 0.076 12.6 2.1 37 4.0 0.0 3.4 2 1 0 3 3 3 0 Leucine Rich repeats (2 copies) AIG2_2 PF13772.1 CAM67411.1 - 4.5e-08 33.0 0.1 1.6e-07 31.3 0.0 2.0 1 0 0 1 1 1 1 AIG2-like family AIG2 PF06094.7 CAM67411.1 - 8.2e-05 23.0 0.1 0.0012 19.3 0.0 2.6 2 1 0 2 2 2 1 AIG2-like family DAO PF01266.19 CAM67412.1 - 4.1e-17 62.1 0.0 1.3e-09 37.4 0.2 3.0 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 CAM67412.1 - 1.5e-07 30.8 0.2 2.4e-07 30.1 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CAM67412.1 - 3.1e-07 29.5 0.1 6.6e-07 28.5 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 CAM67412.1 - 4.8e-06 26.4 0.7 1.2e-05 25.2 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 CAM67412.1 - 1.2e-05 24.4 0.5 4.5e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 CAM67412.1 - 0.00023 19.7 0.3 0.00036 19.1 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 CAM67412.1 - 0.00032 20.6 0.0 0.00059 19.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CAM67412.1 - 0.021 14.9 0.4 0.11 12.5 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CAM67412.1 - 0.036 12.9 1.1 0.063 12.1 0.7 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 CAM67412.1 - 0.056 13.8 0.2 0.056 13.8 0.1 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CAM67412.1 - 0.2 10.7 0.1 0.34 9.9 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Methyltransf_8 PF05148.10 CAM67413.1 - 1.6e-53 181.5 0.0 2.2e-53 181.1 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 CAM67413.1 - 9.8e-08 32.3 0.0 3.8e-07 30.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CAM67413.1 - 0.0067 15.5 0.0 0.027 13.6 0.0 1.9 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 CAM67413.1 - 0.0068 16.1 0.0 0.022 14.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 CAM67413.1 - 0.037 13.1 0.0 0.082 12.0 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB Peptidase_C2 PF00648.16 CAM67418.2 - 9.4e-52 175.8 0.0 1.4e-51 175.2 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 CAM67418.2 - 2.7e-34 117.2 0.1 5.7e-34 116.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Calpain_III PF01067.17 CAM67418.2 - 0.1 12.2 0.0 0.3 10.7 0.0 1.9 2 0 0 2 2 2 0 Calpain large subunit, domain III Rad1 PF02144.11 CAM67419.2 - 3.5e-07 29.2 0.0 0.00051 18.8 0.0 2.1 2 0 0 2 2 2 2 Repair protein Rad1/Rec1/Rad17 NUDIX PF00293.23 CAM67420.1 - 3.7e-09 36.3 0.3 4.7e-05 23.0 0.1 3.4 3 1 0 3 3 3 2 NUDIX domain Metallophos PF00149.23 CAM67421.1 - 0.00031 20.2 0.0 0.00065 19.1 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Cellulase PF00150.13 CAM67421.1 - 0.14 11.3 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Metallophos PF00149.23 CAM67422.1 - 1.9e-06 27.4 0.1 0.00055 19.3 0.0 2.6 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Cellulase PF00150.13 CAM67422.1 - 0.029 13.5 0.0 0.22 10.6 0.0 2.0 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) DUF2946 PF11162.3 CAM67423.1 - 4e-20 72.2 0.1 1.2e-19 70.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2946) Vpu PF00558.14 CAM67423.1 - 0.0037 16.7 0.6 0.0076 15.7 0.4 1.4 1 0 0 1 1 1 1 Vpu protein Shisa PF13908.1 CAM67423.1 - 0.021 15.0 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator NVEALA PF14055.1 CAM67423.1 - 0.022 14.4 0.0 0.075 12.7 0.0 1.9 1 0 0 1 1 1 0 NVEALA protein FAM163 PF15069.1 CAM67423.1 - 0.023 15.2 0.1 0.039 14.5 0.0 1.4 1 0 0 1 1 1 0 FAM163 family EphA2_TM PF14575.1 CAM67423.1 - 0.032 14.6 0.1 0.083 13.2 0.1 1.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4526 PF15029.1 CAM67423.1 - 0.035 13.6 0.1 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4526) LRR19-TM PF15176.1 CAM67423.1 - 0.04 13.6 0.0 0.079 12.6 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain UPF0104 PF03706.8 CAM67423.1 - 0.05 12.8 0.2 0.34 10.1 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0104) DUF4381 PF14316.1 CAM67423.1 - 0.064 13.3 0.1 0.9 9.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF4307 PF14155.1 CAM67423.1 - 0.08 12.7 0.1 6.1 6.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) Chordopox_A13L PF05961.6 CAM67423.1 - 0.13 12.2 0.4 0.24 11.3 0.3 1.4 1 0 0 1 1 1 0 Chordopoxvirus A13L protein FixQ PF05545.6 CAM67423.1 - 0.31 10.7 0.1 0.31 10.7 0.1 2.7 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ DUF1729 PF08354.5 CAM67424.1 - 0.0085 15.8 0.0 0.023 14.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Mito_fiss_reg PF05308.6 CAM67424.1 - 2 7.7 9.8 0.27 10.5 1.7 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator MFS_1 PF07690.11 CAM67425.1 - 6.6e-19 67.8 30.2 3.6e-15 55.5 2.6 2.8 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 CAM67425.1 - 9.3e-06 24.4 13.5 9.3e-06 24.4 9.4 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter Snf7 PF03357.16 CAM67426.1 - 0.0043 16.4 1.2 0.0043 16.4 0.8 4.3 2 1 2 4 4 4 3 Snf7 TTL PF03133.10 CAM67427.1 - 3.5e-47 160.7 0.0 1.6e-44 152.0 0.0 2.4 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family Tubulin_3 PF14881.1 CAM67428.1 - 8.8e-06 25.2 0.0 1.6e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 CAM67428.1 - 0.002 18.1 0.0 0.0042 17.1 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Pkinase PF00069.20 CAM67429.1 - 4.3e-56 189.9 0.0 6.9e-56 189.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM67429.1 - 8.2e-37 126.6 0.0 1.2e-36 126.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.24 CAM67429.1 - 5.8e-15 54.8 0.0 2.3e-05 24.1 0.0 3.7 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain PAS PF00989.19 CAM67429.1 - 8.3e-06 25.5 0.0 2.7e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 PAS fold Kinase-like PF14531.1 CAM67429.1 - 7e-05 21.9 0.0 0.00083 18.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like PAS_4 PF08448.5 CAM67429.1 - 0.0018 18.2 0.1 0.01 15.8 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 CAM67429.1 - 0.0084 16.4 0.0 0.02 15.2 0.0 1.6 1 0 0 1 1 1 1 PAS domain DUF775 PF05603.7 CAM67432.1 - 3.5e-37 127.9 0.0 4.2e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Acyl-CoA_dh_C PF12806.2 CAM67433.1 - 5.4e-05 23.0 0.8 8.6e-05 22.4 0.5 1.3 1 0 0 1 1 1 1 Acetyl-CoA dehydrogenase C-terminal like Tfb2 PF03849.9 CAM67433.1 - 0.0047 15.6 1.1 0.0061 15.2 0.8 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 HEAT_2 PF13646.1 CAM67434.1 - 7.4e-27 93.4 24.7 1.2e-06 28.6 0.1 7.1 3 1 4 7 7 7 7 HEAT repeats HEAT PF02985.17 CAM67434.1 - 1.3e-26 90.2 44.1 0.002 18.0 0.1 13.6 15 0 0 15 15 15 9 HEAT repeat HEAT_EZ PF13513.1 CAM67434.1 - 1.9e-09 37.7 33.7 0.012 16.0 0.0 10.0 6 3 6 12 12 12 4 HEAT-like repeat Vac14_Fab1_bd PF12755.2 CAM67434.1 - 1.6e-06 28.3 0.3 0.0089 16.3 0.0 5.5 2 1 3 6 6 6 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 CAM67434.1 - 1.8e-05 24.2 2.1 0.017 14.4 0.2 4.2 2 1 3 5 5 5 1 CLASP N terminal Adaptin_N PF01602.15 CAM67434.1 - 4.6e-05 21.9 8.9 0.018 13.3 1.6 3.3 1 1 3 4 4 4 4 Adaptin N terminal region TPR_14 PF13428.1 CAM67435.1 - 1.1e-06 28.7 7.4 4.2 8.2 0.0 6.4 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 CAM67435.1 - 0.00087 18.8 0.3 0.014 15.0 0.4 2.7 2 1 0 2 2 2 1 TPR repeat TPR_19 PF14559.1 CAM67435.1 - 0.0028 17.9 0.7 0.25 11.6 0.1 3.7 2 1 2 4 4 4 1 Tetratricopeptide repeat Retro_M PF02813.9 CAM67435.1 - 0.072 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Retroviral M domain Suf PF05843.9 CAM67435.1 - 0.11 12.2 5.0 2.9 7.5 0.1 3.3 2 2 1 3 3 3 0 Suppressor of forked protein (Suf) TPR_2 PF07719.12 CAM67435.1 - 0.17 11.8 3.1 39 4.5 0.2 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 CAM67435.1 - 1.2 9.9 0.0 1.2 9.9 0.0 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat Kinesin PF00225.18 CAM67436.1 - 7.4e-81 271.4 1.9 1.7e-73 247.2 0.0 3.2 3 0 0 3 3 3 2 Kinesin motor domain Snapin_Pallidin PF14712.1 CAM67436.1 - 2.3 8.6 18.0 0.75 10.1 0.1 4.6 3 1 2 5 5 5 0 Snapin/Pallidin Spc7 PF08317.6 CAM67436.1 - 3.8 6.0 13.5 0.64 8.6 1.2 2.8 2 1 1 3 3 3 0 Spc7 kinetochore protein BLOC1_2 PF10046.4 CAM67436.1 - 5.3 7.2 7.5 23 5.1 0.0 3.7 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NTP_transf_2 PF01909.18 CAM67439.1 - 0.01 16.1 0.0 0.02 15.2 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain MORN PF02493.15 CAM67441.1 - 2.5e-27 92.9 32.6 3.8e-07 29.4 0.3 6.6 6 0 0 6 6 6 6 MORN repeat CTP_synth_N PF06418.9 CAM67443.1 - 2.8e-109 364.4 0.0 3.9e-109 364.0 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 CAM67443.1 - 3.2e-42 144.1 0.0 6.6e-42 143.1 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CAM67443.1 - 3.6e-09 36.3 0.1 1.6e-08 34.2 0.0 1.9 2 0 0 2 2 2 1 Peptidase C26 CbiA PF01656.18 CAM67443.1 - 0.00035 20.0 0.0 0.00078 18.8 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CTDII PF01556.13 CAM67444.1 - 1.3e-11 44.2 0.0 4.8e-07 29.5 0.0 3.2 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CAM67444.1 - 1.1e-09 38.2 9.7 2.2e-09 37.2 6.7 1.6 1 0 0 1 1 1 1 DnaJ central domain RWD PF05773.17 CAM67445.1 - 9.4e-10 38.3 0.4 1.6e-09 37.6 0.3 1.3 1 0 0 1 1 1 1 RWD domain MORN PF02493.15 CAM67447.1 - 1.6e-19 68.4 14.7 8.3e-07 28.3 0.1 6.7 6 0 0 6 6 6 4 MORN repeat WW PF00397.21 CAM67447.1 - 0.0095 15.7 0.1 0.025 14.4 0.1 1.8 1 0 0 1 1 1 1 WW domain DUF4404 PF14357.1 CAM67448.1 - 0.21 12.0 2.4 1.2 9.5 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4404) CTP_transf_2 PF01467.21 CAM67449.1 - 0.00013 22.0 0.0 0.00054 20.0 0.0 2.1 2 0 0 2 2 2 1 Cytidylyltransferase CinA PF02464.12 CAM67449.1 - 0.054 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Competence-damaged protein DUF2802 PF10975.3 CAM67449.1 - 0.079 12.7 1.0 0.47 10.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) A2L_zn_ribbon PF08792.5 CAM67450.1 - 0.018 14.4 0.3 0.018 14.4 0.2 1.9 2 0 0 2 2 2 0 A2L zinc ribbon domain DNA_RNApol_7kD PF03604.8 CAM67450.1 - 0.045 13.2 0.7 0.045 13.2 0.5 2.1 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit PhnA_Zn_Ribbon PF08274.7 CAM67450.1 - 0.1 12.3 1.0 9.5 6.1 0.0 2.3 2 0 0 2 2 2 0 PhnA Zinc-Ribbon GFA PF04828.9 CAM67450.1 - 0.14 12.1 2.3 0.31 11.0 0.0 2.2 2 1 1 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme TF_Zn_Ribbon PF08271.7 CAM67450.1 - 0.46 9.8 2.5 7.3 5.9 0.1 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding DUF2318 PF10080.4 CAM67450.1 - 0.58 9.9 2.6 0.39 10.4 0.1 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) DZR PF12773.2 CAM67450.1 - 1.8 8.4 6.4 0.38 10.5 0.2 2.2 2 0 0 2 2 2 0 Double zinc ribbon PPR_2 PF13041.1 CAM67451.1 - 1.4e-12 47.3 0.1 0.00041 20.2 0.0 4.4 3 1 2 5 5 5 4 PPR repeat family PPR PF01535.15 CAM67451.1 - 1.3e-08 34.2 0.1 0.048 13.6 0.0 4.0 4 0 0 4 4 4 3 PPR repeat PPR_3 PF13812.1 CAM67451.1 - 7.5e-08 32.0 0.7 6.6e-05 22.8 0.1 4.2 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR_1 PF12854.2 CAM67451.1 - 0.016 14.7 0.0 0.73 9.3 0.0 3.0 3 0 0 3 3 3 0 PPR repeat Tubulin PF00091.20 CAM67452.1 - 8.7e-73 244.6 0.0 1.2e-72 244.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.1 CAM67452.1 - 0.0071 15.3 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin like TM231 PF10149.4 CAM67453.1 - 1.2e-09 37.6 5.0 1.4e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 Transmembrane protein 231 EF-hand_1 PF00036.27 CAM67453.1 - 0.069 12.4 0.3 0.14 11.5 0.2 1.5 1 0 0 1 1 1 0 EF hand LRR_8 PF13855.1 CAM67456.1 - 3e-09 36.4 3.0 6.9e-05 22.5 0.1 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 CAM67456.1 - 8.9e-09 34.7 2.2 0.00047 19.7 0.1 3.1 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CAM67456.1 - 2.2e-07 29.9 2.2 0.3 11.2 0.0 5.3 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_7 PF13504.1 CAM67456.1 - 3.2e-07 29.4 4.1 0.014 15.4 0.2 4.6 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 CAM67456.1 - 0.0029 17.4 0.6 61 4.1 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich repeat Septum_form PF13845.1 CAM67459.1 - 0.016 14.7 0.1 0.018 14.5 0.1 1.1 1 0 0 1 1 1 0 Septum formation Acetyltransf_13 PF13880.1 CAM67460.1 - 5.7e-22 77.2 0.0 1.3e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase AAA PF00004.24 CAM67461.1 - 7.4e-49 165.3 0.0 1e-36 126.0 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CAM67461.1 - 5.5e-12 46.5 0.3 3.5e-05 24.6 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CAM67461.1 - 5.1e-09 36.3 2.0 0.014 15.5 0.9 4.3 2 2 0 2 2 2 2 AAA domain AAA_19 PF13245.1 CAM67461.1 - 8.7e-09 35.0 0.5 0.0011 18.6 0.0 2.9 3 0 0 3 3 2 2 Part of AAA domain AAA_5 PF07728.9 CAM67461.1 - 1.5e-07 31.2 0.0 0.002 17.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CAM67461.1 - 2.7e-07 30.7 0.1 0.0048 16.9 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.1 CAM67461.1 - 5.6e-07 29.9 0.1 0.022 15.0 0.0 3.0 3 0 0 3 3 3 2 AAA domain TIP49 PF06068.8 CAM67461.1 - 3.9e-06 25.8 0.0 0.019 13.6 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus Mg_chelatase PF01078.16 CAM67461.1 - 1.9e-05 23.9 0.0 0.0026 16.9 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 CAM67461.1 - 0.0001 22.2 0.0 0.89 9.4 0.0 3.3 2 1 1 3 3 3 2 AAA domain RuvB_N PF05496.7 CAM67461.1 - 0.00013 21.0 0.0 0.038 13.0 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 CAM67461.1 - 0.00021 21.4 0.0 0.19 11.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Sigma54_activ_2 PF14532.1 CAM67461.1 - 0.00025 21.1 0.0 0.53 10.3 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.1 CAM67461.1 - 0.00028 20.7 0.0 0.49 10.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.6 CAM67461.1 - 0.0003 20.4 0.0 0.24 10.9 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CAM67461.1 - 0.0004 20.0 0.1 0.26 10.9 0.0 3.7 3 1 0 3 3 3 1 NACHT domain Sigma54_activat PF00158.21 CAM67461.1 - 0.00049 19.6 0.0 0.25 10.7 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.7 CAM67461.1 - 0.00083 18.5 0.0 1.1 8.3 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.12 CAM67461.1 - 0.0011 18.3 0.0 0.047 13.0 0.0 2.9 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_28 PF13521.1 CAM67461.1 - 0.0012 18.7 0.0 1.6 8.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.4 CAM67461.1 - 0.0013 17.7 0.1 1.5 7.7 0.1 2.5 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_2 PF07724.9 CAM67461.1 - 0.0029 17.5 0.0 0.014 15.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_30 PF13604.1 CAM67461.1 - 0.0044 16.6 0.0 4.1 6.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 CAM67461.1 - 0.0085 15.3 0.1 5.3 6.1 0.0 2.8 3 0 0 3 3 3 0 Chromatin associated protein KTI12 T2SE PF00437.15 CAM67461.1 - 0.01 14.7 0.0 2.4 7.0 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_24 PF13479.1 CAM67461.1 - 0.011 15.2 0.1 0.18 11.3 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 CAM67461.1 - 0.012 15.1 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 CAM67461.1 - 0.014 15.7 0.7 0.87 9.8 0.0 3.3 3 1 1 4 4 3 0 ABC transporter KaiC PF06745.8 CAM67461.1 - 0.022 13.8 0.1 1.5 7.8 0.0 2.5 2 0 0 2 2 2 0 KaiC PhoH PF02562.11 CAM67461.1 - 0.022 13.9 0.0 0.92 8.7 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.1 CAM67461.1 - 0.028 13.8 4.0 4.6 6.5 0.1 3.7 3 1 1 4 4 4 0 AAA domain Arch_ATPase PF01637.13 CAM67461.1 - 0.034 13.8 0.3 2.4 7.8 0.1 3.2 2 2 1 3 3 3 0 Archaeal ATPase CDC48_N PF02359.13 CAM67461.1 - 0.06 13.2 0.0 0.26 11.2 0.0 2.1 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain AAA_29 PF13555.1 CAM67461.1 - 0.081 12.4 0.2 6.4 6.3 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain NB-ARC PF00931.17 CAM67461.1 - 0.1 11.4 0.0 0.89 8.3 0.0 2.3 3 0 0 3 3 3 0 NB-ARC domain ResIII PF04851.10 CAM67461.1 - 0.18 11.6 0.1 16 5.2 0.0 2.9 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit ACPS PF01648.15 CAM67463.1 - 7.9e-12 45.0 0.0 1.5e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily SCO1-SenC PF02630.9 CAM67464.1 - 5.2e-31 107.5 0.1 3.4e-29 101.6 0.1 2.5 1 1 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.1 CAM67464.1 - 0.01 15.9 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like AhpC-TSA PF00578.16 CAM67464.1 - 0.044 13.4 0.3 0.63 9.7 0.2 2.3 1 1 0 1 1 1 0 AhpC/TSA family TruD PF01142.13 CAM67465.1 - 8.5e-15 54.2 0.0 1.3e-13 50.3 0.0 2.7 2 1 0 2 2 2 1 tRNA pseudouridine synthase D (TruD) DEAD PF00270.24 CAM67467.1 - 2e-28 99.0 1.0 5.4e-16 58.5 0.0 3.2 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM67467.1 - 5e-14 51.9 0.0 1.2e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAM67467.1 - 5.7e-08 32.8 0.0 3.8e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CAM67467.1 - 0.1 12.7 0.1 7.3 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain Scramblase PF03803.10 CAM67467.1 - 0.11 11.5 0.3 0.2 10.6 0.2 1.3 1 0 0 1 1 1 0 Scramblase Elf1 PF05129.8 CAM67468.1 - 1e-21 76.3 0.4 1.6e-21 75.8 0.3 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zinc_ribbon_5 PF13719.1 CAM67468.1 - 0.011 15.2 0.7 0.022 14.3 0.5 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CAM67468.1 - 0.041 13.5 0.7 0.082 12.6 0.5 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Lar_restr_allev PF14354.1 CAM67468.1 - 0.067 13.5 0.1 0.18 12.1 0.1 1.7 1 0 0 1 1 1 0 Restriction alleviation protein Lar Elf1 PF05129.8 CAM67469.1 - 6e-07 29.0 1.5 2.8e-06 26.9 1.0 2.0 1 1 0 1 1 1 1 Transcription elongation factor Elf1 like DUF2946 PF11162.3 CAM67469.1 - 0.097 12.8 2.0 0.26 11.4 1.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2946) Ribonuclease_3 PF00636.21 CAM67470.1 - 0.00036 20.9 0.0 0.00095 19.6 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease III domain AATF-Che1 PF13339.1 CAM67472.1 - 1.7e-30 105.8 0.0 1.7e-30 105.8 0.0 3.5 4 2 2 6 6 6 1 Apoptosis antagonizing transcription factor TRAUB PF08164.7 CAM67472.1 - 0.012 15.7 1.7 0.035 14.2 0.0 2.7 2 0 0 2 2 2 0 Apoptosis-antagonizing transcription factor, C-terminal DUF4379 PF14311.1 CAM67475.1 - 7.4e-13 48.0 13.6 2.5e-07 30.3 5.7 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4379) SprT-like PF10263.4 CAM67475.1 - 0.036 13.7 0.9 0.071 12.7 0.6 1.4 1 0 0 1 1 1 0 SprT-like family Pkinase PF00069.20 CAM67476.1 - 1.7e-47 161.7 0.1 3.8e-31 108.1 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAM67476.1 - 8.9e-30 103.6 0.0 1.5e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM67476.1 - 0.0013 17.7 0.0 0.0027 16.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PAS_8 PF13188.1 CAM67476.1 - 0.24 11.3 0.0 2.7 7.9 0.0 2.6 2 0 0 2 2 2 0 PAS domain ARD PF03079.9 CAM67477.1 - 1.6e-37 128.8 0.0 2.3e-37 128.3 0.0 1.2 1 0 0 1 1 1 1 ARD/ARD' family DUF953 PF06110.6 CAM67477.1 - 5.8e-15 54.7 0.0 9.5e-15 54.0 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Cupin_2 PF07883.6 CAM67477.1 - 2.8e-09 36.3 0.0 4.8e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 CAM67477.1 - 2.5e-06 27.2 0.1 1.6e-05 24.6 0.0 2.3 3 0 0 3 3 3 1 AraC-like ligand binding domain Cupin_1 PF00190.17 CAM67477.1 - 0.019 14.3 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Cupin GPI PF06560.6 CAM67477.1 - 0.026 13.5 0.0 0.039 12.9 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Glutaredoxin PF00462.19 CAM67481.1 - 5.8e-12 45.4 0.0 8.3e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.1 CAM67481.1 - 0.013 15.3 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain SH3BGR PF04908.10 CAM67481.1 - 0.067 13.1 0.0 0.083 12.8 0.0 1.2 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein BetaGal_dom4_5 PF13364.1 CAM67481.1 - 0.094 12.9 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain Pro-rich PF15240.1 CAM67488.1 - 0.0036 17.4 6.3 0.0044 17.1 4.4 1.1 1 0 0 1 1 1 1 Proline-rich zf-RING_2 PF13639.1 CAM67489.1 - 0.00026 20.7 3.5 0.00076 19.2 2.4 1.9 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CAM67489.1 - 0.02 15.0 13.1 0.05 13.7 9.1 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CAM67489.1 - 0.031 14.3 3.2 0.11 12.5 2.2 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAM67489.1 - 0.12 12.0 8.5 0.57 9.9 5.9 2.2 1 1 0 1 1 1 0 zinc-RING finger domain AAA_22 PF13401.1 CAM67490.1 - 0.001 19.1 0.0 0.0063 16.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CAM67490.1 - 0.004 17.9 0.0 0.013 16.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 CAM67490.1 - 0.0043 17.2 0.0 0.0095 16.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 CAM67490.1 - 0.038 12.8 0.0 0.075 11.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 CAM67490.1 - 0.61 9.7 0.0 1.5 8.4 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase MORN PF02493.15 CAM67491.2 - 1.2e-11 43.5 14.7 0.00036 20.1 0.8 4.6 4 0 0 4 4 4 3 MORN repeat PI3_PI4_kinase PF00454.22 CAM67493.2 - 2.4e-44 151.5 0.1 6.1e-44 150.2 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 CAM67493.2 - 3.2e-34 118.4 2.5 2.1e-33 115.7 1.1 2.5 2 0 0 2 2 2 1 FAT domain FATC PF02260.15 CAM67493.2 - 9.8e-10 37.6 0.0 2.6e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 FATC domain TFCD_C PF12612.3 CAM67493.2 - 0.0001 21.8 2.2 0.00047 19.6 0.1 3.3 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 CAM67493.2 - 0.0012 18.7 2.7 7.2 6.9 0.0 6.2 6 0 0 6 6 6 1 HEAT repeat V-ATPase_H_C PF11698.3 CAM67493.2 - 0.11 12.4 0.9 7.7 6.4 0.0 3.3 3 0 0 3 3 3 0 V-ATPase subunit H DnaJ PF00226.26 CAM67494.1 - 4.6e-19 67.8 0.5 4.6e-19 67.8 0.3 2.3 2 0 0 2 2 2 1 DnaJ domain Myb_DNA-binding PF00249.26 CAM67494.1 - 0.0015 18.5 5.2 0.69 10.0 0.1 3.6 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CAM67494.1 - 0.055 13.5 0.6 0.055 13.5 0.4 3.9 4 0 0 4 4 4 0 Myb-like DNA-binding domain DUF3138 PF11336.3 CAM67494.1 - 1.1 7.3 6.9 0.24 9.5 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) YIF1 PF03878.10 CAM67495.1 - 9e-30 103.5 10.3 2.9e-20 72.4 4.6 2.0 2 0 0 2 2 2 2 YIF1 Yip1 PF04893.12 CAM67495.1 - 7.6e-05 22.2 14.3 0.00017 21.1 9.9 1.5 1 0 0 1 1 1 1 Yip1 domain PRP38 PF03371.10 CAM67496.1 - 2.3e-13 50.1 0.0 3.1e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 PRP38 family Esterase PF00756.15 CAM67498.1 - 5.3e-15 55.5 0.0 6.2e-14 52.0 0.0 2.2 1 1 0 1 1 1 1 Putative esterase CBM_48 PF02922.13 CAM67498.1 - 0.0074 16.3 0.1 0.032 14.2 0.1 2.0 1 1 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) DUF3046 PF11248.3 CAM67498.1 - 0.067 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3046) Peptidase_C2 PF00648.16 CAM67500.2 - 1.4e-51 175.3 0.0 2.2e-51 174.6 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 CAM67500.2 - 3.6e-34 116.8 0.1 7.6e-34 115.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.16 CAM67501.1 - 1.3e-46 158.9 0.0 2.2e-46 158.2 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 CAM67501.1 - 3.6e-33 113.6 0.1 7.7e-33 112.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.16 CAM67502.1 - 4.8e-39 134.1 0.0 6.8e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 CAM67502.1 - 1.5e-25 89.1 0.0 3e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.16 CAM67503.1 - 2.7e-31 108.7 0.0 4.5e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 CAM67503.1 - 2e-20 72.7 0.0 4.7e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.5 CAM67504.1 - 1.9e-25 88.8 0.0 2.4e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.5 CAM67505.1 - 3.7e-29 100.7 0.0 4.2e-29 100.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Raptor_N PF14538.1 CAM67506.1 - 2.6e-10 40.3 0.0 4.8e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain DUF1935 PF09149.5 CAM67507.1 - 1.6e-30 105.1 0.0 2.6e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.5 CAM67508.1 - 0.0046 16.9 0.0 4 7.4 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF1935) DUF1935 PF09149.5 CAM67509.1 - 7e-06 25.9 0.0 1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF3275 PF11679.3 CAM67509.1 - 0.032 13.8 0.6 1.7 8.2 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3275) Cupredoxin_1 PF13473.1 CAM67509.1 - 0.096 12.5 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Cupredoxin-like domain DUF1935 PF09149.5 CAM67510.1 - 7.5e-31 106.1 0.0 9.6e-31 105.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) TMA7 PF09072.5 CAM67510.1 - 0.053 13.9 2.3 0.089 13.2 1.6 1.3 1 0 0 1 1 1 0 Translation machinery associated TMA7 NAP PF00956.13 CAM67511.1 - 4.1e-19 68.6 0.2 5.5e-19 68.2 0.1 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Sipho_Gp157 PF05565.6 CAM67511.1 - 4.8 6.7 8.7 12 5.4 0.3 2.3 2 0 0 2 2 2 0 Siphovirus Gp157 DUF1935 PF09149.5 CAM67512.1 - 2.2e-35 120.7 0.1 2.6e-35 120.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.5 CAM67513.1 - 7.4e-40 135.1 0.4 8.7e-40 134.9 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Pkinase PF00069.20 CAM67515.1 - 1.7e-35 122.4 0.0 2.5e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM67515.1 - 1.5e-18 66.8 0.0 2.4e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM67515.1 - 1.2e-06 27.7 0.0 0.004 16.1 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 CAM67515.1 - 0.14 11.2 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Adaptin_N PF01602.15 CAM67517.1 - 3.6e-63 213.6 6.8 5e-63 213.2 4.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.7 CAM67517.1 - 3.5e-38 130.4 0.0 7.8e-38 129.2 0.0 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.1 CAM67517.1 - 8.7e-38 128.9 0.4 4e-36 123.6 0.2 2.5 1 1 0 1 1 1 1 Coatomer beta subunit appendage platform HEAT_2 PF13646.1 CAM67517.1 - 3.8e-10 39.9 8.9 0.027 14.7 0.0 6.2 3 1 1 6 6 6 3 HEAT repeats HEAT PF02985.17 CAM67517.1 - 8.9e-06 25.3 6.0 0.22 11.7 0.0 5.4 7 0 0 7 7 7 2 HEAT repeat Cnd1 PF12717.2 CAM67517.1 - 0.0015 18.4 8.4 0.56 10.0 1.3 3.6 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 CAM67517.1 - 0.044 13.6 0.3 12 5.8 0.0 3.0 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat RNase_PH PF01138.16 CAM67518.1 - 0.016 15.5 0.0 0.14 12.4 0.0 2.2 2 0 0 2 2 2 0 3' exoribonuclease family, domain 1 PUF PF00806.14 CAM67519.1 - 1e-17 62.5 0.0 0.0028 17.0 0.0 4.4 4 0 0 4 4 4 4 Pumilio-family RNA binding repeat PUF PF00806.14 CAM67520.1 - 7e-18 63.0 0.0 0.0025 17.1 0.0 4.4 4 0 0 4 4 4 4 Pumilio-family RNA binding repeat Striatin PF08232.7 CAM67522.1 - 0.0017 18.6 0.2 0.0017 18.6 0.2 3.8 4 0 0 4 4 4 1 Striatin family Tropomyosin_1 PF12718.2 CAM67522.1 - 0.0034 17.2 5.2 0.3 10.9 0.0 3.0 3 0 0 3 3 3 2 Tropomyosin like Sipho_Gp157 PF05565.6 CAM67522.1 - 0.047 13.2 0.4 0.19 11.2 0.0 2.1 2 0 0 2 2 2 0 Siphovirus Gp157 Ax_dynein_light PF10211.4 CAM67522.1 - 0.14 12.0 8.1 1.1 9.1 0.3 3.0 3 0 0 3 3 3 0 Axonemal dynein light chain TMF_TATA_bd PF12325.3 CAM67522.1 - 0.21 11.3 6.3 6.8 6.4 0.2 3.2 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding KLRAQ PF10205.4 CAM67522.1 - 0.31 11.1 0.0 0.31 11.1 0.0 3.7 4 1 1 5 5 5 0 Predicted coiled-coil domain-containing protein DivIC PF04977.10 CAM67522.1 - 0.35 10.3 12.9 0.053 13.0 0.7 3.2 3 0 0 3 3 3 0 Septum formation initiator DUF641 PF04859.7 CAM67522.1 - 0.39 10.4 9.2 0.18 11.5 0.3 2.9 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) Spc24 PF08286.6 CAM67522.1 - 0.48 10.1 6.1 7.3 6.3 0.1 3.1 3 1 0 3 3 3 0 Spc24 subunit of Ndc80 CENP-F_leu_zip PF10473.4 CAM67522.1 - 0.64 9.8 10.0 0.63 9.8 0.1 3.3 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin_2 PF01920.15 CAM67522.1 - 0.89 9.3 5.5 7.9 6.2 0.6 2.8 3 0 0 3 3 3 0 Prefoldin subunit Clathrin_lg_ch PF01086.12 CAM67522.1 - 2.8 7.7 9.4 2 8.2 2.3 2.8 3 0 0 3 3 3 0 Clathrin light chain Arm PF00514.18 CAM67523.1 - 1e-36 123.5 19.1 1e-06 28.3 0.0 9.1 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CAM67523.1 - 1.7e-23 82.7 16.7 1.3e-06 28.5 0.1 5.1 2 1 3 5 5 5 5 HEAT repeats HEAT PF02985.17 CAM67523.1 - 1.4e-18 65.2 14.6 0.0042 17.0 0.0 8.2 9 0 0 9 9 8 6 HEAT repeat HEAT_EZ PF13513.1 CAM67523.1 - 4.9e-15 55.5 22.2 0.00022 21.6 0.3 6.4 5 1 2 7 7 7 5 HEAT-like repeat Adaptin_N PF01602.15 CAM67523.1 - 1e-11 43.8 1.1 2.6e-08 32.6 1.2 3.2 2 1 1 3 3 3 3 Adaptin N terminal region DNA_alkylation PF08713.6 CAM67523.1 - 8e-09 35.3 0.2 0.0076 15.7 0.0 4.1 2 1 2 4 4 4 3 DNA alkylation repair enzyme Proteasom_PSMB PF10508.4 CAM67523.1 - 4.1e-08 31.9 3.0 0.00085 17.7 0.3 3.3 1 1 1 3 3 3 2 Proteasome non-ATPase 26S subunit Cnd1 PF12717.2 CAM67523.1 - 1.4e-07 31.4 0.1 0.00019 21.3 0.0 3.3 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 CAM67523.1 - 4.1e-05 23.0 0.8 0.37 10.1 0.2 3.1 2 1 1 3 3 3 2 CLASP N terminal V-ATPase_H_C PF11698.3 CAM67523.1 - 0.0015 18.4 0.6 0.5 10.2 0.2 3.9 3 2 2 5 5 5 1 V-ATPase subunit H DUF3731 PF12531.3 CAM67523.1 - 0.008 15.7 2.3 2.5 7.5 0.1 3.5 2 1 1 4 4 4 1 DNA-K related protein HEAT_PBS PF03130.11 CAM67523.1 - 0.0085 16.4 15.3 0.68 10.5 1.5 6.2 6 1 0 6 6 5 1 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.2 CAM67523.1 - 0.011 16.0 0.1 0.83 10.0 0.0 3.3 1 1 3 4 4 4 0 Vacuolar 14 Fab1-binding region OHCU_decarbox PF09349.5 CAM67523.1 - 0.031 14.5 1.5 8 6.7 0.0 3.4 2 1 1 3 3 3 0 OHCU decarboxylase DUF3361 PF11841.3 CAM67523.1 - 0.041 13.5 2.3 5.2 6.7 0.0 3.6 2 2 2 4 4 4 0 Domain of unknown function (DUF3361) XPC-binding PF09280.6 CAM67523.1 - 0.055 12.9 0.0 37 3.8 0.0 3.9 3 0 0 3 3 3 0 XPC-binding domain ubiquitin PF00240.18 CAM67528.1 - 4.5e-05 22.7 0.0 0.12 11.8 0.0 3.0 4 0 0 4 4 4 2 Ubiquitin family DUF3450 PF11932.3 CAM67528.1 - 0.017 14.4 2.4 0.031 13.5 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Rabaptin PF03528.10 CAM67528.1 - 0.073 12.9 3.2 0.17 11.7 2.2 1.6 1 0 0 1 1 1 0 Rabaptin Spc7 PF08317.6 CAM67528.1 - 0.091 11.4 1.2 0.18 10.4 0.8 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Retrotrans_gag PF03732.12 CAM67528.1 - 1.5 8.9 4.2 5.5 7.1 3.0 1.9 1 1 0 1 1 1 0 Retrotransposon gag protein DUF2802 PF10975.3 CAM67528.1 - 4.4 7.1 8.4 3.3 7.5 3.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2802) DUF3154 PF11351.3 CAM67528.1 - 7.9 6.2 8.1 5 6.8 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3154) PPR_3 PF13812.1 CAM67530.1 - 0.035 14.3 1.4 1.1 9.7 0.1 3.6 3 0 0 3 3 3 0 Pentatricopeptide repeat domain Sporozoite_P67 PF05642.6 CAM67530.1 - 0.14 9.9 0.1 0.19 9.5 0.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Myotub-related PF06602.9 CAM67531.2 - 1.2e-83 280.8 0.0 3.5e-83 279.2 0.0 1.8 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 CAM67531.2 - 0.0035 17.6 0.0 0.0094 16.2 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family FYVE PF01363.16 CAM67531.2 - 0.14 12.1 11.7 0.45 10.4 8.1 1.8 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.11 CAM67531.2 - 0.18 11.6 8.5 0.51 10.2 5.9 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger C1_4 PF07975.7 CAM67531.2 - 0.34 10.9 12.0 1.2 9.1 8.3 2.0 1 0 0 1 1 1 0 TFIIH C1-like domain HEAT_EZ PF13513.1 CAM67532.1 - 0.02 15.4 1.6 0.17 12.4 0.1 3.4 3 0 0 3 3 3 0 HEAT-like repeat RabGAP-TBC PF00566.13 CAM67533.1 - 2.9e-17 62.8 0.0 4.6e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SGS PF05002.10 CAM67534.1 - 5.8e-30 102.8 0.5 8.9e-30 102.2 0.4 1.3 1 0 0 1 1 1 1 SGS domain CS PF04969.11 CAM67534.1 - 7.8e-08 32.7 0.0 1.3e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 CS domain Ribosomal_S17 PF00366.15 CAM67535.1 - 6.6e-27 93.3 1.2 1.1e-26 92.6 0.9 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 Brix PF04427.13 CAM67537.1 - 4.5e-33 114.5 0.0 6.6e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 Brix domain Peptidase_C50 PF03568.12 CAM67538.1 - 7.2e-29 100.6 0.0 4.5e-14 51.9 0.0 3.2 3 0 0 3 3 3 3 Peptidase family C50 CHAT PF12770.2 CAM67538.1 - 7.2e-10 38.4 1.5 3.3e-05 23.1 0.1 2.9 3 0 0 3 3 3 2 CHAT domain SNAP PF14938.1 CAM67539.1 - 5.7e-57 193.0 15.2 6.6e-57 192.8 10.5 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 CAM67539.1 - 2.5e-08 33.7 9.3 3.4e-07 30.1 0.9 2.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 CAM67539.1 - 0.00062 19.3 12.7 0.0061 16.1 2.3 3.1 3 1 0 3 3 3 2 TPR repeat TPR_8 PF13181.1 CAM67539.1 - 0.023 14.4 10.9 0.031 14.0 0.4 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat DUF1033 PF06279.6 CAM67539.1 - 0.024 14.4 1.1 0.024 14.4 0.7 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1033) TPR_7 PF13176.1 CAM67539.1 - 0.024 14.3 2.9 5.3 7.0 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Kunitz_BPTI PF00014.18 CAM67539.1 - 0.061 13.5 1.4 1.3 9.2 0.2 2.5 2 0 0 2 2 2 0 Kunitz/Bovine pancreatic trypsin inhibitor domain Apc3 PF12895.2 CAM67539.1 - 0.4 10.8 6.8 0.25 11.5 1.0 2.9 2 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Foie-gras_1 PF11817.3 CAM67539.1 - 0.55 9.6 4.3 0.31 10.4 0.4 2.4 2 1 0 2 2 2 0 Foie gras liver health family 1 TPR_1 PF00515.23 CAM67539.1 - 0.64 9.7 13.9 0.35 10.5 0.3 4.5 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 CAM67539.1 - 0.81 10.4 10.6 6.8 7.4 0.5 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 CAM67539.1 - 2 9.0 19.8 12 6.6 0.2 5.8 4 3 1 6 6 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 CAM67539.1 - 7.1 7.0 13.8 1.1 9.6 0.5 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 CAM67539.1 - 8.2 6.4 11.4 2.7 7.9 0.1 4.2 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain DUF3306 PF11748.3 CAM67540.1 - 0.67 10.6 2.8 0.47 11.1 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3306) tRNA_U5-meth_tr PF05958.6 CAM67541.1 - 3.6e-17 62.0 0.0 3.3e-16 58.9 0.0 2.0 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 CAM67541.1 - 4.7e-14 52.2 0.0 7.9e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CAM67541.1 - 4.6e-09 36.3 0.0 9.9e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAM67541.1 - 4.1e-08 33.7 0.0 9.4e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CAM67541.1 - 4.4e-07 29.4 0.0 8.9e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 CAM67541.1 - 8.1e-07 29.3 0.0 2.2e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 CAM67541.1 - 9.5e-07 28.3 0.0 1.6e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PCMT PF01135.14 CAM67541.1 - 1.1e-05 25.0 0.0 2.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 CAM67541.1 - 7.8e-05 21.9 0.3 0.00023 20.3 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 CAM67541.1 - 9.5e-05 22.8 0.0 0.00048 20.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.5 CAM67541.1 - 0.00038 20.0 0.0 0.00063 19.3 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_4 PF02390.12 CAM67541.1 - 0.002 17.2 0.0 0.0038 16.2 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 CAM67541.1 - 0.0055 15.8 0.1 0.0092 15.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 CAM67541.1 - 0.01 15.5 0.0 0.031 13.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain TPMT PF05724.6 CAM67541.1 - 0.012 15.0 0.0 0.14 11.6 0.0 2.1 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) DOT1 PF08123.8 CAM67541.1 - 0.016 14.5 0.1 0.031 13.5 0.1 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 UPF0020 PF01170.13 CAM67541.1 - 0.018 14.6 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 RNA_ligase PF09414.5 CAM67543.1 - 3.7e-52 176.8 0.0 3.2e-51 173.7 0.0 2.1 2 0 0 2 2 2 1 RNA ligase DNA_ligase_A_M PF01068.16 CAM67543.1 - 0.001 18.4 0.0 0.0024 17.2 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain OST-HTH PF12872.2 CAM67544.1 - 0.043 13.6 0.0 0.099 12.4 0.0 1.6 2 0 0 2 2 2 0 OST-HTH/LOTUS domain DUF4455 PF14643.1 CAM67548.1 - 2.4e-11 42.9 2.3 2.4e-11 42.9 1.6 5.2 6 2 1 7 7 7 1 Domain of unknown function (DUF4455) DUF4456 PF14644.1 CAM67548.1 - 9.5e-10 38.0 0.0 9.5e-10 38.0 0.0 4.3 4 0 0 4 4 4 1 Domain of unknown function (DUF4456) V_ATPase_I PF01496.14 CAM67548.1 - 1.4 6.6 4.3 0.52 8.1 0.7 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family AAA PF00004.24 CAM67549.1 - 3.3e-26 92.0 0.0 2.2e-25 89.3 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CAM67549.1 - 0.00014 21.9 0.0 0.0022 18.1 0.0 2.8 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CAM67549.1 - 0.0013 19.0 0.0 0.0036 17.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 CAM67549.1 - 0.005 16.8 0.8 0.005 16.8 0.6 4.2 3 2 1 4 4 4 1 AAA ATPase domain AAA_17 PF13207.1 CAM67549.1 - 0.012 16.4 0.0 0.037 14.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CAM67549.1 - 0.029 14.2 0.3 0.12 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CAM67549.1 - 0.03 13.8 0.0 0.073 12.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TIP49 PF06068.8 CAM67549.1 - 0.039 12.6 0.0 0.063 11.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Arch_ATPase PF01637.13 CAM67549.1 - 0.13 11.9 0.0 1.1 8.9 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase AAA_14 PF13173.1 CAM67549.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CAM67549.1 - 0.18 11.4 4.6 1.6 8.3 0.1 3.4 2 2 0 2 2 2 0 NACHT domain DUF1534 PF07551.6 CAM67549.1 - 0.27 10.7 3.5 5.7 6.5 1.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1534) AAA_21 PF13304.1 CAM67549.1 - 0.39 10.6 0.0 0.53 10.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain RVT_1 PF00078.22 CAM67550.1 - 0.0065 15.8 0.0 0.0073 15.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_M20 PF01546.23 CAM67551.1 - 1.4e-24 86.6 0.1 1.8e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CAM67551.1 - 6.5e-10 38.7 0.0 1.5e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 CAM67551.1 - 0.045 13.4 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 Peptidase_M20 PF01546.23 CAM67552.2 - 5.2e-29 101.0 0.1 6.7e-29 100.7 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CAM67552.2 - 1.5e-09 37.5 0.0 4.3e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 CAM67552.2 - 0.091 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 PPR_2 PF13041.1 CAM67553.1 - 9.1e-15 54.3 8.3 1.7e-05 24.7 0.0 6.0 7 0 0 7 7 7 3 PPR repeat family PPR_3 PF13812.1 CAM67553.1 - 2.2e-13 49.3 10.2 0.0031 17.6 0.0 8.1 8 0 0 8 8 8 3 Pentatricopeptide repeat domain PPR_1 PF12854.2 CAM67553.1 - 5.2e-05 22.6 0.0 0.12 11.8 0.0 4.6 5 0 0 5 5 5 1 PPR repeat PPR PF01535.15 CAM67553.1 - 0.0001 22.0 9.1 0.3 11.1 0.6 5.7 7 0 0 7 7 7 2 PPR repeat Pkr1 PF08636.5 CAM67554.1 - 0.023 14.7 7.6 0.03 14.3 5.3 1.2 1 0 0 1 1 1 0 ER protein Pkr1 2TM PF13239.1 CAM67554.1 - 4.3 7.4 6.5 7.3 6.7 4.5 1.4 1 1 0 1 1 1 0 2TM domain DUF3730 PF12530.3 CAM67555.1 - 0.018 14.9 0.0 0.18 11.7 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3730) DUF1442 PF07279.6 CAM67555.1 - 0.029 13.4 0.1 0.058 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) GTP_cyclohydro2 PF00925.15 CAM67555.1 - 0.11 11.7 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 GTP cyclohydrolase II CHORD PF04968.7 CAM67557.1 - 4.2e-45 151.8 32.1 1.1e-22 80.0 8.2 2.3 2 0 0 2 2 2 2 CHORD Calpain_III PF01067.17 CAM67743.1 - 4.2e-29 101.0 0.0 3.1e-25 88.5 0.0 3.5 3 1 0 3 3 3 3 Calpain large subunit, domain III DUF3876 PF12992.2 CAM67743.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3876) Topoisom_bac PF01131.15 CAM67744.1 - 4.6e-81 272.6 0.0 3.1e-80 269.9 0.0 2.1 2 1 0 2 2 2 1 DNA topoisomerase Toprim PF01751.17 CAM67744.1 - 4.8e-12 45.7 0.0 1.5e-11 44.1 0.0 1.9 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.1 CAM67744.1 - 0.0078 16.1 0.0 0.028 14.4 0.0 1.9 2 0 0 2 2 2 1 Toprim domain FleQ PF06490.6 CAM67744.1 - 0.014 15.5 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ ACDC PF14733.1 CAM67744.1 - 0.087 12.9 0.0 1.6 8.8 0.0 2.7 3 0 0 3 3 3 0 AP2-coincident C-terminal Pkinase PF00069.20 CAM67745.1 - 1.2e-54 185.2 0.0 1.9e-54 184.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM67745.1 - 2.4e-31 108.7 0.0 4e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM67745.1 - 0.0011 18.0 0.0 0.003 16.5 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CAM67745.1 - 0.024 13.7 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Guanylate_cyc PF00211.15 CAM67745.1 - 0.064 12.6 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain SH PF01445.12 CAM67745.1 - 0.15 11.7 10.8 0.016 14.8 2.5 2.6 2 0 0 2 2 2 0 Viral small hydrophobic protein Pkinase PF00069.20 CAM67747.1 - 2.2e-39 135.2 0.0 2.9e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM67747.1 - 5.1e-13 48.7 0.0 1.1e-12 47.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM67747.1 - 0.0006 18.8 0.0 0.0011 18.0 0.0 1.4 1 1 0 1 1 1 1 Kinase-like LRR_6 PF13516.1 CAM67748.1 - 1.7e-13 49.1 7.2 0.0047 16.8 0.0 9.6 11 0 0 11 11 11 2 Leucine Rich repeat LRR_4 PF12799.2 CAM67748.1 - 9.5e-11 41.0 6.3 0.0067 16.0 0.0 6.8 6 2 1 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM67748.1 - 1.3e-10 40.8 12.6 0.00011 21.8 0.1 6.6 6 1 1 7 7 7 4 Leucine rich repeat LRR_1 PF00560.28 CAM67748.1 - 3.5e-06 26.2 8.7 16 6.0 0.0 9.3 10 0 0 10 10 10 1 Leucine Rich Repeat LRR_7 PF13504.1 CAM67748.1 - 0.0023 17.8 22.4 7.4 7.2 0.1 10.0 11 0 0 11 11 11 1 Leucine rich repeat PUF PF00806.14 CAM67749.1 - 0.023 14.1 3.3 6.4 6.4 0.0 4.8 5 1 1 6 6 6 0 Pumilio-family RNA binding repeat CHAT PF12770.2 CAM67750.2 - 1.4e-42 145.7 0.3 2.8e-42 144.8 0.2 1.5 1 0 0 1 1 1 1 CHAT domain LRR_6 PF13516.1 CAM67750.2 - 6.5e-08 31.8 6.4 0.28 11.3 0.0 4.4 4 0 0 4 4 4 3 Leucine Rich repeat TPR_12 PF13424.1 CAM67750.2 - 0.0016 18.3 2.4 0.0016 18.3 1.6 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat LRR_4 PF12799.2 CAM67750.2 - 0.19 11.3 8.0 2.9 7.5 2.0 2.8 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CAM67750.2 - 0.56 10.4 7.2 20 5.7 1.7 3.5 2 1 0 2 2 2 0 Leucine Rich Repeat TPR_11 PF13414.1 CAM67750.2 - 1.8 8.2 15.4 1.8 8.2 0.1 4.8 3 2 2 5 5 5 0 TPR repeat TPR_2 PF07719.12 CAM67750.2 - 5.1 7.2 14.5 3.1 7.9 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat MVP_shoulder PF11978.3 CAM67752.1 - 4.6e-45 152.3 0.0 7.6e-45 151.5 0.0 1.4 1 0 0 1 1 1 1 Shoulder domain Vault PF01505.13 CAM67752.1 - 1.7e-30 104.7 3.8 3.9e-12 45.9 0.1 5.4 5 0 0 5 5 5 3 Major Vault Protein repeat EF-hand_7 PF13499.1 CAM67754.1 - 1e-12 47.9 0.0 1.5e-05 25.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CAM67754.1 - 1.3e-10 40.2 1.8 0.00075 19.1 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 CAM67754.1 - 1.7e-09 36.2 0.0 0.017 14.3 0.0 3.5 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 CAM67754.1 - 1.1e-06 28.0 0.1 0.0029 17.1 0.1 3.3 1 1 3 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.1 CAM67754.1 - 2e-06 27.6 0.2 0.0011 18.8 0.0 2.8 2 1 1 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 CAM67754.1 - 0.059 12.7 5.4 1.1 8.7 0.0 3.1 3 1 0 3 3 3 0 EF hand Actin PF00022.14 CAM67755.1 - 3.5e-34 117.8 0.0 6e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 Actin Hexokinase_1 PF00349.16 CAM67756.1 - 4.5e-64 215.5 0.1 7e-64 214.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 CAM67756.1 - 1.4e-53 181.6 0.0 2.1e-53 181.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 CAM67757.1 - 4.5e-64 215.5 0.1 7e-64 214.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 CAM67757.1 - 6.1e-54 182.7 0.0 9.4e-54 182.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase PPR_2 PF13041.1 CAM67758.1 - 4.9e-13 48.8 0.6 1.6e-06 28.0 0.0 5.0 4 1 1 5 5 5 3 PPR repeat family PPR_3 PF13812.1 CAM67758.1 - 1.6e-11 43.5 11.6 0.19 12.0 0.0 9.0 10 1 0 10 10 10 5 Pentatricopeptide repeat domain PPR PF01535.15 CAM67758.1 - 0.00022 20.9 5.0 5.1 7.3 0.0 6.7 7 0 0 7 7 7 1 PPR repeat PPR_1 PF12854.2 CAM67758.1 - 0.00077 18.8 1.0 0.089 12.2 0.0 3.4 3 0 0 3 3 3 1 PPR repeat ECSIT PF06239.6 CAM67758.1 - 0.098 11.5 0.1 0.53 9.1 0.0 2.1 3 0 0 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway Pkinase PF00069.20 CAM67759.1 - 1.2e-45 155.6 0.0 1.6e-44 152.0 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM67759.1 - 7.7e-30 103.8 0.0 3.7e-22 78.6 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase RIO1 PF01163.17 CAM67759.1 - 2.9e-05 23.5 0.1 5.8e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 RIO1 family SUZ PF12752.2 CAM67759.1 - 0.054 14.0 0.1 0.054 14.0 0.1 2.2 2 0 0 2 2 2 0 SUZ domain Kdo PF06293.9 CAM67759.1 - 0.15 11.1 0.1 0.27 10.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CAM67759.1 - 0.28 10.0 0.0 3.7 6.4 0.0 2.1 2 0 0 2 2 2 0 Kinase-like MHC_I_C PF06623.6 CAM67760.1 - 0.1 12.0 0.9 0.68 9.4 0.4 2.4 2 0 0 2 2 2 0 MHC_I C-terminus LRR_4 PF12799.2 CAM67761.1 - 0.006 16.1 0.6 3.2 7.4 0.0 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) DUF702 PF05142.7 CAM67763.1 - 0.021 14.9 0.2 0.039 14.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF702) DUF2115 PF09888.4 CAM67763.1 - 0.048 13.7 0.0 0.072 13.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) zf-U1 PF06220.7 CAM67764.1 - 9.1e-05 21.9 4.1 0.0002 20.8 2.9 1.6 1 0 0 1 1 1 1 U1 zinc finger AKAP95 PF04988.7 CAM67764.1 - 0.0085 15.8 0.3 0.013 15.2 0.2 1.3 1 0 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_jaz PF12171.3 CAM67764.1 - 0.011 15.8 0.9 0.026 14.6 0.6 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 CAM67764.1 - 0.42 11.0 2.0 3.7 8.0 1.4 2.3 1 1 0 1 1 1 0 C2H2-type zinc finger Vps51 PF08700.6 CAM67765.1 - 2.2e-24 85.0 1.9 6.3e-24 83.6 1.3 1.9 1 0 0 1 1 1 1 Vps51/Vps67 Sec5 PF15469.1 CAM67765.1 - 8.7e-10 38.6 0.6 7.1e-09 35.6 0.5 2.1 2 1 0 2 2 2 1 Exocyst complex component Sec5 Dor1 PF04124.7 CAM67765.1 - 1.3e-06 27.1 2.2 2.4e-06 26.2 1.5 1.3 1 0 0 1 1 1 1 Dor1-like family Vps53_N PF04100.7 CAM67765.1 - 1.5e-05 23.9 2.1 2.6e-05 23.2 1.5 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 CAM67765.1 - 1.7e-05 23.9 3.4 3.1e-05 23.0 2.3 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 CAM67765.1 - 3.3e-05 23.7 1.7 0.00015 21.6 1.2 2.1 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.4 CAM67765.1 - 0.0015 18.4 3.2 0.0061 16.5 2.2 2.1 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Transposase_22 PF02994.9 CAM67765.1 - 0.0027 16.2 0.6 0.0044 15.5 0.4 1.2 1 0 0 1 1 1 1 L1 transposable element Prominin PF05478.6 CAM67765.1 - 0.01 13.4 1.0 0.017 12.6 0.7 1.2 1 0 0 1 1 1 0 Prominin CENP-F_leu_zip PF10473.4 CAM67765.1 - 0.21 11.4 7.3 0.082 12.7 2.5 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cluap1 PF10234.4 CAM67765.1 - 0.56 9.3 6.4 0.99 8.5 1.0 2.3 2 0 0 2 2 2 0 Clusterin-associated protein-1 Peptidase_M16 PF00675.15 CAM67766.1 - 1.1e-13 51.2 0.0 3.5e-13 49.5 0.0 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CAM67766.1 - 0.00042 20.0 0.0 0.0043 16.7 0.0 2.5 2 1 0 2 2 2 1 Peptidase M16 inactive domain DUF607 PF04678.8 CAM67767.1 - 9.6e-29 100.5 5.6 1.1e-28 100.4 3.9 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF607 CCDC92 PF14916.1 CAM67768.1 - 0.062 12.9 0.1 0.062 12.9 0.1 1.8 2 0 0 2 2 2 0 Coiled-coil domain of unknown function RPAP2_Rtr1 PF04181.8 CAM67769.1 - 6.9e-09 35.6 0.0 1.7e-07 31.2 0.0 2.3 1 1 0 1 1 1 1 Rtr1/RPAP2 family DUF667 PF05018.8 CAM67770.1 - 2.7e-102 339.8 0.6 3e-102 339.6 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) PDDEXK_1 PF12705.2 CAM67771.1 - 0.00011 21.7 0.0 0.00019 20.8 0.0 1.5 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily UCH PF00443.24 CAM67772.1 - 5.5e-52 176.5 0.1 8.8e-52 175.8 0.1 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CAM67772.1 - 1.4e-22 80.5 1.5 2.7e-22 79.5 1.1 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Alpha-2-MRAP_N PF06400.6 CAM67772.1 - 1.7e-05 24.4 0.9 3.4e-05 23.4 0.6 1.4 1 0 0 1 1 1 1 Alpha-2-macroglobulin RAP, N-terminal domain Piwi PF02171.12 CAM67773.1 - 4.5e-08 32.4 0.0 6.9e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Piwi domain Pyr_redox_2 PF07992.9 CAM67774.1 - 4.6e-06 26.6 0.0 7.5e-05 22.6 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CAM67774.1 - 5.4e-05 23.3 0.9 0.066 13.2 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CAM67774.1 - 5.5e-05 23.1 0.0 0.00029 20.7 0.0 2.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 CAM67774.1 - 0.0011 18.8 0.0 0.0023 17.6 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 CAM67774.1 - 0.0027 18.0 0.2 0.16 12.3 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase MRP-S31 PF15433.1 CAM67775.1 - 0.012 15.0 4.3 0.018 14.4 3.0 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Kua-UEV1_localn PF10520.4 CAM67776.1 - 1.8e-72 242.7 2.2 2.3e-72 242.3 1.5 1.1 1 0 0 1 1 1 1 Kua-ubiquitin conjugating enzyme hybrid localisation domain DUF2208 PF09973.4 CAM67776.1 - 0.069 12.3 0.1 0.21 10.8 0.0 1.7 1 1 0 2 2 2 0 Predicted membrane protein (DUF2208) FA_hydroxylase PF04116.8 CAM67776.1 - 0.69 10.3 10.2 2.1 8.7 0.3 2.4 1 1 2 3 3 3 0 Fatty acid hydroxylase superfamily Vps35 PF03635.12 CAM67779.1 - 7.4e-252 837.8 0.0 8.6e-252 837.6 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 CALCOCO1 PF07888.6 CAM67780.1 - 0.00025 19.4 14.8 0.00025 19.4 10.3 1.7 2 0 0 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like EABR PF12180.3 CAM67780.1 - 0.007 15.6 0.8 0.023 14.0 0.6 1.9 1 0 0 1 1 1 1 TSG101 and ALIX binding domain of CEP55 Tropomyosin PF00261.15 CAM67780.1 - 0.049 12.7 23.3 0.13 11.3 0.1 3.1 2 1 1 3 3 3 0 Tropomyosin DUF4600 PF15372.1 CAM67780.1 - 0.12 12.6 3.3 0.13 12.4 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) DUF972 PF06156.8 CAM67780.1 - 0.21 11.9 6.0 0.97 9.8 0.6 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF972) DUF444 PF04285.7 CAM67780.1 - 0.97 8.0 4.4 0.3 9.6 0.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF444) Spc7 PF08317.6 CAM67780.1 - 3.6 6.1 10.6 2.9 6.4 4.0 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein ING PF12998.2 CAM67780.1 - 3.9 7.8 6.5 1.8 8.8 1.2 2.6 1 1 2 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Cortex-I_coil PF09304.5 CAM67780.1 - 8.6 6.4 16.5 0.63 10.1 4.0 3.2 1 1 2 3 3 3 0 Cortexillin I, coiled coil DnaJ PF00226.26 CAM67781.1 - 1e-26 92.4 1.2 1.7e-26 91.7 0.8 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CAM67781.1 - 3.9e-19 68.3 0.0 1.4e-16 60.1 0.0 3.1 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CAM67781.1 - 1.8e-14 53.5 11.9 3.4e-14 52.6 8.3 1.5 1 0 0 1 1 1 1 DnaJ central domain RNA_pol_3_Rpc31 PF11705.3 CAM67781.1 - 0.0064 16.4 1.4 0.013 15.4 1.0 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 HypA PF01155.14 CAM67781.1 - 0.11 12.1 3.6 0.58 9.8 0.4 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_5 PF13719.1 CAM67781.1 - 0.82 9.3 3.2 18 5.0 0.4 2.8 2 0 0 2 2 2 0 zinc-ribbon domain DUF2318 PF10080.4 CAM67781.1 - 2.3 8.0 4.7 1.6 8.5 0.2 2.3 1 1 0 2 2 2 0 Predicted membrane protein (DUF2318) DZR PF12773.2 CAM67781.1 - 2.3 8.0 8.8 7.3 6.5 0.9 2.5 1 1 1 2 2 2 0 Double zinc ribbon Herpes_UL21 PF03252.8 CAM67783.2 - 0.00077 18.0 0.5 0.0015 17.0 0.4 1.4 1 0 0 1 1 1 1 Herpesvirus UL21 TPR_11 PF13414.1 CAM67785.1 - 5.4e-17 61.2 12.3 1.2e-05 24.7 0.0 6.6 3 2 3 6 6 6 4 TPR repeat TPR_14 PF13428.1 CAM67785.1 - 5.2e-16 57.6 37.8 0.009 16.5 0.2 10.5 7 2 3 10 10 9 7 Tetratricopeptide repeat TPR_19 PF14559.1 CAM67785.1 - 3.1e-15 56.2 14.7 0.00053 20.2 0.0 6.7 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 CAM67785.1 - 7.9e-14 51.8 35.9 5.5e-05 23.7 0.2 9.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.12 CAM67785.1 - 1.6e-13 49.4 19.1 0.0091 15.8 0.4 8.7 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.1 CAM67785.1 - 1.1e-12 47.6 16.7 0.0052 16.7 0.5 6.6 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 CAM67785.1 - 3.8e-11 42.1 7.8 0.011 15.3 0.4 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 CAM67785.1 - 1.1e-07 31.8 13.7 0.0046 17.0 0.4 5.2 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CAM67785.1 - 2e-07 30.2 0.1 2.4 8.1 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 CAM67785.1 - 4.5e-07 29.1 8.3 2.7 8.0 0.0 6.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 CAM67785.1 - 4e-05 23.3 13.8 0.01 15.6 0.1 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 CAM67785.1 - 0.0028 17.9 15.3 4.4 7.9 0.0 6.6 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 CAM67785.1 - 0.27 11.5 17.3 20 5.6 0.2 6.9 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_10 PF13374.1 CAM67785.1 - 0.34 10.9 19.4 0.39 10.7 0.1 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat NARP1 PF12569.3 CAM67785.1 - 0.39 9.4 0.0 23 3.5 0.0 2.3 1 1 0 2 2 2 0 NMDA receptor-regulated protein 1 La PF05383.12 CAM67786.1 - 2e-21 75.5 0.0 4.3e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 CAM67786.1 - 5.2e-06 26.0 0.5 0.0014 18.2 0.1 3.3 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM67786.1 - 7.6e-06 25.8 0.0 0.014 15.3 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CAM67786.1 - 0.0026 17.5 2.1 0.0099 15.7 0.2 2.6 3 0 0 3 3 3 1 RNA binding motif RRM_5 PF13893.1 CAM67786.1 - 0.0032 17.2 0.2 0.35 10.7 0.0 2.7 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) API5 PF05918.6 CAM67786.1 - 0.013 14.0 1.5 0.022 13.2 1.0 1.4 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Biotin_lipoyl PF00364.17 CAM67787.1 - 3e-27 94.0 2.0 1.7e-12 46.7 0.1 2.4 2 0 0 2 2 2 2 Biotin-requiring enzyme E3_binding PF02817.12 CAM67787.1 - 0.0056 16.2 0.3 0.055 13.1 0.2 2.8 1 1 0 1 1 1 1 e3 binding domain QRPTase_N PF02749.11 CAM67787.1 - 0.011 15.5 0.1 7.4 6.4 0.0 2.6 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain DUF2118 PF09891.4 CAM67787.1 - 0.018 14.7 0.1 7.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) PYNP_C PF07831.8 CAM67787.1 - 0.018 14.4 0.3 8.6 5.9 0.0 2.6 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain HlyD_3 PF13437.1 CAM67787.1 - 0.038 14.3 0.4 13 6.2 0.0 2.4 2 0 0 2 2 2 0 HlyD family secretion protein Glyco_hydro_66 PF13199.1 CAM67787.1 - 0.086 11.2 2.3 4 5.7 0.1 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 66 DUF902 PF06001.8 CAM67787.1 - 0.11 12.6 0.1 24 5.1 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF902) DUF3123 PF11321.3 CAM67787.1 - 0.44 10.8 19.4 1.3 9.3 0.7 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3123) TALPID3 PF15324.1 CAM67787.1 - 3 5.0 12.6 1.1 6.4 1.4 2.1 2 0 0 2 2 2 0 Hedgehog signalling target SNARE PF05739.14 CAM67788.1 - 1.7e-07 30.8 5.7 2e-07 30.5 3.9 1.1 1 0 0 1 1 1 1 SNARE domain ocr PF08684.5 CAM67788.1 - 0.074 13.0 0.7 1.2 9.1 0.0 2.1 1 1 1 2 2 2 0 DNA mimic ocr CTD_bind PF04818.8 CAM67790.1 - 0.2 11.9 0.1 0.86 9.8 0.0 2.0 2 0 0 2 2 2 0 RNA polymerase II-binding domain. DEAD PF00270.24 CAM67793.1 - 6.8e-16 58.2 0.0 6.6e-12 45.2 0.0 3.2 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM67793.1 - 4.7e-14 52.0 0.0 1.1e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAM67793.1 - 0.014 15.2 0.0 0.056 13.2 0.0 2.0 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit MSP1_C PF07462.6 CAM67793.1 - 0.065 11.6 6.2 1.5 7.0 1.2 2.2 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus SecA_DEAD PF07517.9 CAM67793.1 - 0.081 12.1 0.1 0.19 10.9 0.0 1.6 1 0 0 1 1 1 0 SecA DEAD-like domain Med3 PF11593.3 CAM67793.1 - 0.19 10.9 8.8 0.037 13.2 0.4 2.4 3 0 0 3 3 3 0 Mediator complex subunit 3 fungal IMS PF00817.15 CAM67794.1 - 3.3e-40 137.2 0.4 6.1e-40 136.4 0.3 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 CAM67794.1 - 0.0004 20.3 0.0 0.0008 19.3 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 CAM67794.1 - 0.0031 17.4 0.0 0.0061 16.5 0.0 1.5 1 0 0 1 1 1 1 IMS family HHH motif IMS PF00817.15 CAM67795.1 - 1.1e-47 161.6 0.4 1.5e-47 161.1 0.3 1.2 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 CAM67795.1 - 1.9e-07 31.0 0.0 3.8e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 CAM67795.1 - 0.0031 17.4 0.0 0.0059 16.5 0.0 1.5 1 0 0 1 1 1 1 IMS family HHH motif PGM_PMM_I PF02878.11 CAM67796.1 - 1.5e-31 108.6 0.1 2.5e-31 107.9 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 CAM67796.1 - 1.2e-24 86.4 0.0 2.8e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 CAM67796.1 - 2e-11 43.7 0.0 4.9e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.11 CAM67796.1 - 2.1e-10 40.8 0.1 1.6e-09 38.0 0.1 2.4 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II ParA PF10609.4 CAM67798.1 - 2e-33 114.0 0.0 4e-33 113.1 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 CAM67798.1 - 1.7e-18 66.7 0.0 2.3e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 CAM67798.1 - 7.7e-07 29.1 0.0 2e-06 27.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain MipZ PF09140.6 CAM67798.1 - 9.9e-07 28.0 0.0 1.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 CAM67798.1 - 0.0019 17.3 2.4 0.0023 17.0 0.9 1.6 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_17 PF13207.1 CAM67798.1 - 0.0026 18.5 0.0 0.0043 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 CAM67798.1 - 0.0027 16.5 0.3 0.0042 15.8 0.2 1.2 1 0 0 1 1 1 1 ArgK protein AAA_16 PF13191.1 CAM67798.1 - 0.0081 16.1 0.1 0.014 15.3 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 CAM67798.1 - 0.0091 15.1 0.1 0.021 14.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 CAM67798.1 - 0.0094 15.3 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 CAM67798.1 - 0.021 14.5 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 CAM67798.1 - 0.028 14.7 0.0 0.047 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CAM67798.1 - 0.034 13.8 0.7 2.1 8.1 0.1 2.4 2 0 0 2 2 2 0 Part of AAA domain AAA_10 PF12846.2 CAM67798.1 - 0.043 13.2 0.4 0.085 12.2 0.3 1.4 1 0 0 1 1 1 0 AAA-like domain Fer4_NifH PF00142.13 CAM67798.1 - 0.053 12.6 0.2 0.1 11.7 0.1 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NB-ARC PF00931.17 CAM67798.1 - 0.069 12.0 0.2 0.11 11.3 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.1 CAM67798.1 - 0.12 11.9 2.1 0.12 11.8 0.3 1.8 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 CAM67798.1 - 0.15 11.7 0.2 0.28 10.8 0.2 1.4 1 0 0 1 1 1 0 NTPase SRP54 PF00448.17 CAM67798.1 - 0.16 11.4 0.6 0.47 9.8 0.2 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_26 PF13500.1 CAM67798.1 - 0.16 11.5 0.1 15 5.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CAM67798.1 - 0.16 11.5 3.0 0.29 10.6 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 CAM67798.1 - 0.18 12.0 0.1 0.33 11.1 0.1 1.4 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 CAM67798.1 - 0.2 11.2 0.6 0.36 10.4 0.4 1.4 1 0 0 1 1 1 0 NACHT domain Lactamase_B PF00753.22 CAM67799.1 - 3.5e-23 82.2 1.3 9.2e-23 80.8 0.1 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CAM67799.1 - 0.00012 21.6 0.1 0.00046 19.7 0.1 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CAM67799.1 - 0.00085 19.0 0.0 0.0021 17.7 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Hist_deacetyl PF00850.14 CAM67800.1 - 1.4e-65 221.6 0.1 1.9e-65 221.2 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DSPc PF00782.15 CAM67802.1 - 1.5e-19 69.8 0.0 2.2e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain ABC_tran PF00005.22 CAM67803.1 - 1.2e-36 125.9 0.0 9.4e-18 64.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CAM67803.1 - 4.6e-15 56.3 2.2 0.007 16.3 0.0 4.6 3 2 2 5 5 5 3 AAA domain SMC_N PF02463.14 CAM67803.1 - 5.7e-11 42.0 2.8 0.00057 19.1 0.1 3.8 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain RLI PF04068.10 CAM67803.1 - 8.7e-09 34.8 5.7 8.7e-09 34.8 3.9 1.8 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Fer4 PF00037.22 CAM67803.1 - 9.7e-08 31.3 2.2 9.7e-08 31.3 1.5 2.2 2 0 0 2 2 1 1 4Fe-4S binding domain AAA_15 PF13175.1 CAM67803.1 - 1.1e-06 27.9 0.0 0.2 10.6 0.0 3.5 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 CAM67803.1 - 2.4e-06 26.9 0.4 0.01 15.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 CAM67803.1 - 1.3e-05 25.6 0.1 0.0097 16.2 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CAM67803.1 - 2.5e-05 24.3 0.0 0.0083 16.1 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CAM67803.1 - 6.8e-05 23.0 0.1 0.015 15.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 CAM67803.1 - 7.6e-05 22.3 0.0 0.00088 18.9 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Fer4_6 PF12837.2 CAM67803.1 - 8.6e-05 22.2 2.1 8.6e-05 22.2 1.5 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Miro PF08477.8 CAM67803.1 - 8.9e-05 22.9 0.2 0.016 15.6 0.0 2.7 2 1 0 2 2 2 1 Miro-like protein AAA_17 PF13207.1 CAM67803.1 - 0.00018 22.2 0.1 0.25 12.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain Fer4_21 PF14697.1 CAM67803.1 - 0.00021 21.1 16.8 0.00049 19.9 11.7 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain NACHT PF05729.7 CAM67803.1 - 0.00023 20.8 0.3 0.0072 16.0 0.0 2.3 2 0 0 2 2 2 1 NACHT domain DUF258 PF03193.11 CAM67803.1 - 0.00024 20.3 0.1 0.099 11.8 0.0 2.7 3 0 0 3 3 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 CAM67803.1 - 0.00025 20.4 0.0 0.56 9.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 CAM67803.1 - 0.00033 20.8 0.0 0.024 14.8 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Fer4_7 PF12838.2 CAM67803.1 - 0.00037 20.8 0.3 0.00037 20.8 0.2 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_28 PF13521.1 CAM67803.1 - 0.00053 19.9 0.0 0.61 10.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 CAM67803.1 - 0.00085 19.4 0.0 0.43 10.7 0.0 3.2 3 0 0 3 3 3 1 RNA helicase AAA_33 PF13671.1 CAM67803.1 - 0.001 18.9 0.1 0.29 11.0 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_5 PF07728.9 CAM67803.1 - 0.0015 18.2 0.3 0.45 10.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Fer4_10 PF13237.1 CAM67803.1 - 0.0033 17.1 1.6 0.0033 17.1 1.1 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain SRP54 PF00448.17 CAM67803.1 - 0.0044 16.4 0.3 0.64 9.4 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_14 PF13173.1 CAM67803.1 - 0.0047 16.8 0.0 0.37 10.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CAM67803.1 - 0.0054 17.0 0.1 3.7 7.8 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 CAM67803.1 - 0.0078 15.8 0.0 2.8 7.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain VirE PF05272.6 CAM67803.1 - 0.0083 15.6 0.0 1.8 7.9 0.0 2.7 2 0 0 2 2 2 1 Virulence-associated protein E Fer4_2 PF12797.2 CAM67803.1 - 0.0087 15.9 2.2 0.0087 15.9 1.5 2.7 2 0 0 2 2 2 1 4Fe-4S binding domain SbcCD_C PF13558.1 CAM67803.1 - 0.0089 15.9 0.1 0.83 9.6 0.0 2.7 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Fer4_3 PF12798.2 CAM67803.1 - 0.014 15.9 4.7 0.014 15.9 3.2 2.6 2 0 0 2 2 1 0 4Fe-4S binding domain Rad17 PF03215.10 CAM67803.1 - 0.017 13.8 0.1 2.9 6.4 0.0 2.7 2 1 1 3 3 3 0 Rad17 cell cycle checkpoint protein MobB PF03205.9 CAM67803.1 - 0.021 14.5 0.6 1 9.0 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 CAM67803.1 - 0.044 13.5 0.4 4.4 7.1 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain Arch_ATPase PF01637.13 CAM67803.1 - 0.055 13.1 0.0 0.33 10.6 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase MMR_HSR1 PF01926.18 CAM67803.1 - 0.067 13.1 0.4 5.3 7.0 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_13 PF13166.1 CAM67803.1 - 0.14 10.6 2.8 0.36 9.2 0.0 2.4 3 0 0 3 3 2 0 AAA domain DUF815 PF05673.8 CAM67803.1 - 0.14 11.0 0.1 5.6 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Fer4_9 PF13187.1 CAM67803.1 - 0.14 12.3 14.2 0.74 10.1 10.0 2.2 1 1 0 1 1 1 0 4Fe-4S dicluster domain NB-ARC PF00931.17 CAM67803.1 - 0.15 10.8 0.4 4.5 6.0 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain PduV-EutP PF10662.4 CAM67803.1 - 0.23 10.9 1.7 0.7 9.3 0.0 2.5 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Fer4_4 PF12800.2 CAM67803.1 - 7.1 7.2 15.9 0.068 13.5 1.7 2.6 2 0 0 2 2 1 0 4Fe-4S binding domain Dabb PF07876.7 CAM67804.1 - 0.11 12.9 0.1 0.45 10.9 0.0 1.9 2 0 0 2 2 2 0 Stress responsive A/B Barrel Domain Leu_Phe_trans PF03588.9 CAM67805.1 - 0.00018 20.6 0.0 0.0012 18.0 0.0 2.1 3 0 0 3 3 3 1 Leucyl/phenylalanyl-tRNA protein transferase Ribosomal_L36e PF01158.13 CAM67806.1 - 6.7e-34 115.7 1.7 8.1e-34 115.5 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e DUF543 PF04418.7 CAM67807.1 - 1.9e-19 69.3 0.3 2.3e-19 69.1 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) DLH PF01738.13 CAM67807.1 - 0.0011 18.3 0.1 0.0012 18.2 0.1 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family ATP-synt_C PF00137.16 CAM67808.1 - 4.1e-16 58.6 13.8 4.1e-16 58.6 9.6 1.5 2 0 0 2 2 2 1 ATP synthase subunit C Tetraspannin PF00335.15 CAM67808.1 - 6.4 5.9 8.5 8.3 5.6 5.9 1.2 1 0 0 1 1 1 0 Tetraspanin family PCI PF01399.22 CAM67810.1 - 6e-13 49.0 1.7 1.2e-12 48.0 0.2 2.4 2 0 0 2 2 2 1 PCI domain Vps39_1 PF10366.4 CAM67810.1 - 0.071 13.1 8.3 1.4 8.9 1.0 3.5 1 1 1 3 3 3 0 Vacuolar sorting protein 39 domain 1 DUF4485 PF14846.1 CAM67812.1 - 0.13 11.9 0.0 0.54 10.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4485) Ras PF00071.17 CAM67813.1 - 5.9e-46 155.8 0.0 7.3e-46 155.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAM67813.1 - 5e-20 72.1 0.0 6.8e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAM67813.1 - 1.8e-10 40.3 0.0 3.3e-10 39.4 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CAM67813.1 - 4e-07 29.6 0.0 8.4e-07 28.6 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CAM67813.1 - 0.00015 21.0 0.0 0.0002 20.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CAM67813.1 - 0.00028 20.8 0.0 0.00043 20.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CAM67813.1 - 0.032 13.4 0.0 0.069 12.3 0.0 1.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 CAM67813.1 - 0.099 12.7 0.0 0.3 11.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain Not1 PF04054.10 CAM67814.1 - 1.2e-111 373.2 8.2 2.3e-111 372.3 5.7 1.4 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 CAM67814.1 - 2.2e-30 105.3 0.3 8e-30 103.4 0.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) tRNA-synt_1g PF09334.6 CAM67815.1 - 1.3e-114 382.9 0.2 1.7e-114 382.5 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CAM67815.1 - 2.2e-19 68.9 1.6 7.4e-09 34.1 1.0 3.1 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 CAM67815.1 - 4.7e-08 32.5 0.0 0.002 17.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 CAM67815.1 - 0.036 12.8 0.6 0.35 9.6 0.3 2.3 2 1 1 3 3 3 0 tRNA synthetases class I (R) MKT1_N PF12247.3 CAM67816.1 - 1.1e-21 76.8 0.0 2.3e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_C PF12246.3 CAM67816.1 - 2.4e-14 52.9 0.0 4.1e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication Pkinase PF00069.20 CAM67817.2 - 2.5e-40 138.2 0.0 8.6e-40 136.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM67817.2 - 3.4e-25 88.5 0.0 3.9e-15 55.6 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase APH PF01636.18 CAM67817.2 - 0.0034 17.1 1.7 0.023 14.4 0.0 2.6 3 1 0 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.20 CAM67818.2 - 7.8e-52 175.9 0.0 1.7e-36 125.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAM67818.2 - 8.4e-28 97.1 0.0 2.9e-18 65.8 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CAM67818.2 - 2.9e-09 36.3 0.0 5.7e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like BAG PF02179.11 CAM67819.1 - 0.00071 19.6 0.1 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 BAG domain Reo_sigmaC PF04582.7 CAM67822.1 - 0.002 17.3 4.4 0.028 13.5 0.6 2.2 1 1 1 2 2 2 2 Reovirus sigma C capsid protein ERM PF00769.14 CAM67822.1 - 7.3 6.0 48.8 0.75 9.2 17.7 4.1 3 1 1 4 4 4 0 Ezrin/radixin/moesin family DivIC PF04977.10 CAM67822.1 - 8.8 5.8 15.4 1.8 8.0 0.7 4.3 3 1 1 4 4 4 0 Septum formation initiator LRR_4 PF12799.2 CAM67826.1 - 8.5e-24 82.7 11.2 5.2e-08 32.3 1.5 6.5 6 1 1 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM67826.1 - 1.6e-21 75.8 11.3 2.5e-09 36.7 0.6 5.7 4 2 3 7 7 7 5 Leucine rich repeat LRR_1 PF00560.28 CAM67826.1 - 1.5e-19 67.0 5.3 0.0059 16.4 0.0 10.9 11 0 0 11 11 11 4 Leucine Rich Repeat LRR_6 PF13516.1 CAM67826.1 - 1.8e-05 24.3 12.9 0.42 10.8 0.1 8.5 9 0 0 9 9 9 1 Leucine Rich repeat LRRNT_2 PF08263.7 CAM67826.1 - 0.032 14.2 0.2 0.032 14.2 0.2 3.3 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain Qn_am_d_aIV PF09100.5 CAM67826.1 - 0.078 12.6 0.1 1.8 8.2 0.0 2.9 1 1 2 3 3 3 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain IV LRR_7 PF13504.1 CAM67826.1 - 0.11 12.7 0.6 0.11 12.7 0.4 8.8 10 0 0 10 10 10 0 Leucine rich repeat Ribosomal_L1 PF00687.16 CAM67827.1 - 4.4e-10 39.2 0.0 9.8e-10 38.1 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family PIF1 PF05970.9 CAM67828.1 - 1.3e-33 116.4 0.0 2.9e-23 82.4 0.0 3.7 2 1 1 3 3 3 3 PIF1-like helicase AAA_30 PF13604.1 CAM67828.1 - 1.7e-09 37.5 2.7 7.3e-08 32.2 0.4 2.7 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 CAM67828.1 - 5.7e-07 29.2 3.4 8.8e-07 28.5 1.1 2.3 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 CAM67828.1 - 2.3e-06 27.3 0.1 0.062 12.8 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 CAM67828.1 - 0.00023 21.2 0.0 0.00056 20.0 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DEAD PF00270.24 CAM67828.1 - 0.00063 19.2 0.1 0.023 14.1 0.1 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_5 PF07728.9 CAM67828.1 - 0.0024 17.6 0.1 0.055 13.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_32 PF13654.1 CAM67828.1 - 0.0046 15.6 0.0 0.0068 15.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CAM67828.1 - 0.0051 15.9 0.2 0.01 14.9 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI UvrD-helicase PF00580.16 CAM67828.1 - 0.0054 16.0 0.0 0.0086 15.4 0.0 1.3 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Herpes_Helicase PF02689.9 CAM67828.1 - 0.0062 14.3 0.0 0.023 12.4 0.0 1.8 2 0 0 2 2 2 1 Helicase PhoH PF02562.11 CAM67828.1 - 0.0089 15.2 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein AAA_22 PF13401.1 CAM67828.1 - 0.013 15.6 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 CAM67828.1 - 0.014 15.0 0.9 0.51 9.8 0.0 2.5 1 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CAM67828.1 - 0.016 14.7 0.0 0.04 13.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2075 PF09848.4 CAM67828.1 - 0.033 13.1 0.0 0.12 11.2 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 CAM67828.1 - 0.074 11.9 0.1 0.17 10.7 0.1 1.6 1 1 0 1 1 1 0 Type II/IV secretion system protein NTPase_1 PF03266.10 CAM67828.1 - 0.12 12.0 0.1 0.45 10.1 0.0 1.9 1 1 0 1 1 1 0 NTPase TK PF00265.13 CAM67830.1 - 5.3e-62 208.4 0.7 6.7e-62 208.1 0.5 1.1 1 0 0 1 1 1 1 Thymidine kinase AAA_14 PF13173.1 CAM67830.1 - 0.0016 18.2 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Cytochrome_C7 PF14522.1 CAM67830.1 - 0.089 12.4 1.5 0.2 11.3 1.0 1.6 1 0 0 1 1 1 0 Cytochrome c7 Pox_A_type_inc PF04508.7 CAM67831.1 - 0.97 9.3 19.4 1.2 9.0 0.7 5.6 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat WD40 PF00400.27 CAM67832.1 - 5.2e-19 67.3 6.2 1.8e-07 30.7 0.1 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat PQQ_3 PF13570.1 CAM67832.1 - 0.0034 17.6 7.2 0.5 10.7 0.0 4.5 6 0 0 6 6 6 2 PQQ-like domain WD40 PF00400.27 CAM67833.1 - 2.2e-15 55.8 7.0 6.5e-07 28.9 0.1 4.5 3 0 0 3 3 3 2 WD domain, G-beta repeat IncA PF04156.9 CAM67833.1 - 0.0011 18.6 10.9 0.0011 18.6 7.5 4.9 5 1 0 5 5 5 2 IncA protein SlyX PF04102.7 CAM67833.1 - 0.032 14.6 0.5 0.032 14.6 0.4 7.2 7 1 2 9 9 9 0 SlyX PQQ_3 PF13570.1 CAM67833.1 - 0.048 13.9 0.0 17 5.8 0.1 3.8 4 0 0 4 4 4 0 PQQ-like domain ADK PF00406.17 CAM67834.1 - 7e-39 133.1 0.0 9.9e-39 132.6 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 CAM67834.1 - 1.4e-06 28.6 0.0 8.1e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CAM67834.1 - 4.1e-06 27.6 0.0 9.9e-06 26.3 0.0 1.7 1 1 1 2 2 2 1 AAA domain ADK_lid PF05191.9 CAM67834.1 - 8.6e-05 22.1 0.0 0.00041 19.9 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.1 CAM67834.1 - 0.00013 21.8 0.0 0.00053 19.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CAM67834.1 - 0.15 11.1 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin KTI12 PF08433.5 CAM67834.1 - 0.16 11.1 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 LRR_6 PF13516.1 CAM67835.1 - 0.00048 19.9 1.6 0.67 10.1 0.2 3.6 3 0 0 3 3 3 1 Leucine Rich repeat LRR_4 PF12799.2 CAM67835.1 - 0.038 13.6 2.2 0.26 10.9 0.6 2.2 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CAM67835.1 - 0.08 13.0 5.7 2.7 8.3 0.3 3.5 2 1 1 3 3 3 0 Leucine Rich Repeat LRR_8 PF13855.1 CAM67835.1 - 0.49 10.1 3.5 34 4.3 0.0 2.9 1 1 2 3 3 3 0 Leucine rich repeat LRR_7 PF13504.1 CAM67835.1 - 3.5 8.2 6.1 12 6.6 0.2 3.4 3 0 0 3 3 3 0 Leucine rich repeat Serine_rich PF08824.5 CAM67836.1 - 0.014 15.0 0.0 0.051 13.2 0.0 1.8 2 0 0 2 2 2 0 Serine rich protein interaction domain SelR PF01641.13 CAM67837.1 - 0.0034 17.0 0.1 0.24 11.0 0.0 2.3 2 0 0 2 2 2 2 SelR domain Synaptobrevin PF00957.16 CAM67838.1 - 5.7e-26 89.9 0.4 8.9e-26 89.3 0.3 1.3 1 0 0 1 1 1 1 Synaptobrevin zf-RING_2 PF13639.1 CAM67839.1 - 4.1e-12 45.7 4.2 9.2e-10 38.2 1.0 2.4 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.2 CAM67839.1 - 2e-09 37.3 0.4 3.5e-07 30.2 0.2 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CAM67839.1 - 8.7e-07 28.4 2.5 4.1e-06 26.3 0.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAM67839.1 - 3.5e-05 23.7 5.2 5.8e-05 23.0 1.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CAM67839.1 - 7.6e-05 22.4 0.2 0.00016 21.4 0.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 CAM67839.1 - 0.00017 21.1 2.8 0.00097 18.7 0.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAM67839.1 - 0.0017 18.0 1.9 0.0061 16.2 0.3 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-Nse PF11789.3 CAM67839.1 - 0.053 13.0 0.3 0.13 11.7 0.2 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 CAM67839.1 - 0.062 12.8 0.3 0.062 12.8 0.2 1.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 CAM67839.1 - 0.46 10.5 4.7 0.15 12.1 0.8 1.9 2 0 0 2 2 2 0 RING-variant domain zf-C3HC4_4 PF15227.1 CAM67839.1 - 1.4 8.8 7.0 0.11 12.3 1.0 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 CAM67839.1 - 2.3 8.2 4.9 7.4 6.6 1.8 2.6 2 1 0 2 2 2 0 FANCL C-terminal domain RF-1 PF00472.15 CAM67840.1 - 7.7e-11 41.8 0.7 7.7e-11 41.8 0.5 3.3 3 1 1 4 4 4 1 RF-1 domain CCDC155 PF14662.1 CAM67840.1 - 0.00061 19.4 10.6 0.00061 19.4 7.3 3.4 3 1 0 3 3 3 1 Coiled-coil region of CCDC155 SYCE1 PF15233.1 CAM67840.1 - 0.0059 16.5 7.5 0.0059 16.5 5.2 3.6 3 1 0 4 4 4 1 Synaptonemal complex central element protein 1 DUF4250 PF14056.1 CAM67840.1 - 0.12 12.0 2.3 0.32 10.7 0.4 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4250) Laminin_II PF06009.7 CAM67840.1 - 0.88 9.3 14.2 0.25 11.1 6.3 2.8 2 1 0 2 2 2 0 Laminin Domain II IncA PF04156.9 CAM67840.1 - 1.5 8.3 29.6 0.42 10.1 13.4 3.4 2 1 1 3 3 3 0 IncA protein V_ATPase_I PF01496.14 CAM67840.1 - 5.1 4.8 8.8 14 3.3 6.0 1.7 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3390 PF11870.3 CAM67841.1 - 0.14 12.0 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3390) L6_membrane PF05805.7 CAM67842.2 - 0.016 14.7 0.4 0.02 14.4 0.3 1.1 1 0 0 1 1 1 0 L6 membrane protein SMC_N PF02463.14 CAM67843.2 - 5.2e-70 235.1 12.5 4.5e-69 232.0 8.7 3.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CAM67843.2 - 1.7e-21 76.4 0.0 7.2e-21 74.3 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CAM67843.2 - 6e-13 49.4 0.1 5.1e-06 26.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CAM67843.2 - 6.8e-06 25.5 0.0 1.3e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 CAM67843.2 - 9.9e-05 21.5 0.2 0.0084 15.2 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.1 CAM67843.2 - 0.00021 21.6 25.0 0.00021 21.6 17.3 5.5 3 2 0 3 3 3 1 AAA domain ABC_tran PF00005.22 CAM67843.2 - 0.079 13.2 0.0 0.079 13.2 0.0 5.0 6 1 0 6 6 6 0 ABC transporter V-ATPase_H_N PF03224.9 CAM67844.1 - 2.6e-72 243.5 0.1 3.6e-72 243.1 0.1 1.1 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 CAM67844.1 - 5.9e-42 142.3 0.0 3.6e-41 139.7 0.0 2.1 2 0 0 2 2 2 1 V-ATPase subunit H PB1 PF00564.19 CAM67845.1 - 1.1e-07 31.4 0.0 4e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 PB1 domain AA_permease_2 PF13520.1 CAM67848.1 - 0.063 11.8 0.1 0.1 11.1 0.1 1.2 1 0 0 1 1 1 0 Amino acid permease zf-DHHC PF01529.15 CAM67849.1 - 5e-32 110.6 3.1 5e-32 110.6 2.2 2.7 3 1 0 3 3 3 1 DHHC palmitoyltransferase DUF971 PF06155.7 CAM67850.1 - 3.7e-15 56.1 0.1 2.6e-14 53.3 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF971) DUF393 PF04134.7 CAM67851.1 - 0.00081 20.4 1.3 0.042 14.9 0.1 2.3 2 1 0 2 2 2 2 Protein of unknown function, DUF393 Toxin_22 PF08092.6 CAM67851.1 - 0.014 15.2 1.6 0.028 14.2 1.1 1.4 1 0 0 1 1 1 0 Magi peptide toxin family E1_dh PF00676.15 CAM67852.1 - 8.3e-79 264.4 0.0 1.1e-78 264.0 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF4440 PF14534.1 CAM67852.1 - 0.063 13.4 0.0 0.3 11.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) Cyt-b5 PF00173.23 CAM67853.1 - 1.9e-09 37.2 0.0 3e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Rad60-SLD PF11976.3 CAM67853.1 - 0.0084 15.7 0.0 0.026 14.1 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PRMT5 PF05185.11 CAM67854.1 - 2.2e-70 237.8 0.0 3e-70 237.3 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase TPR_2 PF07719.12 CAM67856.1 - 2.3e-05 23.9 4.1 0.00016 21.2 0.3 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CAM67856.1 - 0.00061 19.6 6.9 0.016 15.1 0.9 3.9 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 CAM67856.1 - 0.00082 18.8 3.3 0.0028 17.2 0.8 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CAM67856.1 - 0.0011 18.6 0.1 0.34 10.7 0.2 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 CAM67856.1 - 0.0034 17.2 10.2 0.017 15.0 0.0 3.1 4 0 0 4 4 4 2 MIT (microtubule interacting and transport) domain TPR_11 PF13414.1 CAM67856.1 - 0.0035 16.9 7.1 0.029 14.0 0.8 2.9 2 2 1 3 3 3 2 TPR repeat Cas_DxTHG PF09455.5 CAM67856.1 - 0.0038 16.4 0.0 0.005 16.0 0.0 1.2 1 0 0 1 1 1 1 CRISPR-associated (Cas) DxTHG family Fis1_TPR_C PF14853.1 CAM67856.1 - 0.0074 16.1 0.2 0.025 14.4 0.2 1.9 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat DUF3529 PF12046.3 CAM67856.1 - 0.035 13.1 0.0 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3529) TPR_14 PF13428.1 CAM67856.1 - 0.056 14.1 5.5 1.1 10.1 0.1 4.6 4 1 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 CAM67856.1 - 0.062 13.2 2.3 0.59 10.1 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Hemerythrin PF01814.18 CAM67856.1 - 0.085 13.0 0.7 0.7 10.0 0.0 2.6 3 0 0 3 3 3 0 Hemerythrin HHE cation binding domain Apc3 PF12895.2 CAM67856.1 - 0.24 11.5 3.1 0.37 10.9 0.4 2.5 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CAM67856.1 - 0.73 10.4 9.0 0.86 10.1 0.2 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat HMG_box PF00505.14 CAM67861.1 - 3.9e-07 30.2 5.9 0.0038 17.4 0.2 4.0 2 2 2 4 4 4 3 HMG (high mobility group) box HMG_box_2 PF09011.5 CAM67861.1 - 6.8e-07 29.5 7.1 0.016 15.5 1.5 3.6 3 1 0 3 3 3 2 HMG-box domain HMG_box_5 PF14887.1 CAM67861.1 - 0.2 11.4 3.2 0.36 10.6 0.2 2.7 2 1 0 2 2 2 0 HMG (high mobility group) box 5 DUF647 PF04884.9 CAM67862.2 - 7.4e-77 257.9 1.4 1e-76 257.4 0.9 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis CK2S PF15011.1 CAM67864.1 - 0.045 13.5 0.0 0.058 13.1 0.0 1.2 1 0 0 1 1 1 0 Casein Kinase 2 substrate peroxidase PF00141.18 CAM67865.1 - 8.2e-10 38.5 0.0 1e-08 34.9 0.0 2.2 1 1 0 2 2 2 1 Peroxidase Chordopox_A13L PF05961.6 CAM67867.1 - 0.22 11.4 0.1 0.22 11.4 0.1 2.7 3 0 0 3 3 3 0 Chordopoxvirus A13L protein Nodulin-like PF06813.8 CAM67867.1 - 3.6 6.7 31.4 0.047 12.9 7.8 3.3 3 0 0 3 3 3 0 Nodulin-like GST_C_3 PF14497.1 CAM67868.1 - 0.0052 17.2 0.0 0.011 16.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain LETM1 PF07766.8 CAM67869.1 - 0.00049 19.2 0.0 0.00085 18.4 0.0 1.3 1 0 0 1 1 1 1 LETM1-like protein DEAD PF00270.24 CAM67870.1 - 3.6e-35 120.9 0.3 4.3e-34 117.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM67870.1 - 4.3e-22 77.7 0.5 1.3e-21 76.1 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAM67870.1 - 3.2e-07 30.3 0.0 6.5e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 CAM67870.1 - 0.00086 18.4 0.1 0.0049 15.9 0.0 2.2 1 1 1 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Helicase_C_2 PF13307.1 CAM67870.1 - 0.12 12.2 0.8 0.29 11.0 0.0 2.0 2 0 0 2 2 2 0 Helicase C-terminal domain Metallothio_Cad PF07846.6 CAM67871.1 - 0.26 11.2 0.9 0.26 11.2 0.7 2.0 2 0 0 2 2 2 0 Metallothionein family DUF4018 PF13210.1 CAM67872.1 - 0.013 14.8 0.1 0.022 14.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4018) A2M PF00207.17 CAM67872.1 - 0.079 12.5 0.1 0.32 10.5 0.0 1.9 2 0 0 2 2 2 0 Alpha-2-macroglobulin family Arv1 PF04161.8 CAM67872.1 - 4.1 7.2 7.9 1.2 9.0 3.5 1.4 2 0 0 2 2 2 0 Arv1-like family Ribosomal_S17 PF00366.15 CAM67873.1 - 6.6e-27 93.3 1.2 1.1e-26 92.6 0.9 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 Sec8_exocyst PF04048.9 CAM67874.1 - 1.3e-10 41.1 0.1 3.8e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 CAM67874.1 - 8.9e-06 24.8 0.1 1.5e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) TrbI_Ftype PF09677.5 CAM67876.1 - 0.039 13.7 1.8 0.15 11.9 0.0 2.5 2 1 1 3 3 3 0 Type-F conjugative transfer system protein (TrbI_Ftype) PMEI PF04043.10 CAM67876.1 - 0.054 13.3 0.2 0.81 9.5 0.1 2.2 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor GAS PF13851.1 CAM67876.1 - 0.081 12.1 7.1 0.2 10.8 3.7 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding SlyX PF04102.7 CAM67876.1 - 0.21 11.9 2.1 2.1 8.7 0.4 2.8 3 0 0 3 3 3 0 SlyX Med29 PF11568.3 CAM67876.1 - 0.41 10.6 4.0 0.87 9.6 0.0 2.2 1 1 1 2 2 2 0 Mediator complex subunit 29 Lge1 PF11488.3 CAM67876.1 - 0.46 10.7 5.6 1.5 9.1 3.9 2.1 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 zf-Sec23_Sec24 PF04810.10 CAM67877.1 - 0.086 12.4 5.9 0.1 12.2 0.1 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger DNA_RNApol_7kD PF03604.8 CAM67877.1 - 0.22 11.0 0.2 0.22 11.0 0.1 2.1 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Rad60-SLD_2 PF13881.1 CAM67878.1 - 1.8e-05 24.5 2.9 0.00026 20.8 2.0 2.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CAM67878.1 - 0.0025 17.9 0.0 0.0038 17.3 0.0 1.4 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain GTP1_OBG PF01018.17 CAM67878.1 - 0.016 14.8 0.7 0.078 12.6 0.1 2.0 1 1 1 2 2 2 0 GTP1/OBG PPR_2 PF13041.1 CAM67879.1 - 2.7e-07 30.4 0.2 7e-07 29.1 0.1 1.7 1 0 0 1 1 1 1 PPR repeat family PPR_3 PF13812.1 CAM67879.1 - 0.00016 21.6 2.9 0.0011 19.0 0.0 3.6 5 0 0 5 5 5 1 Pentatricopeptide repeat domain PPR PF01535.15 CAM67879.1 - 0.0054 16.6 0.7 0.019 14.9 0.0 2.3 3 0 0 3 3 3 1 PPR repeat EF-hand_7 PF13499.1 CAM67880.1 - 2.8e-25 88.2 13.0 5.2e-11 42.5 1.4 2.9 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 CAM67880.1 - 7.2e-24 81.2 7.8 2.5e-06 26.3 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 CAM67880.1 - 3.9e-18 63.6 8.5 9.9e-05 21.9 0.2 4.8 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 CAM67880.1 - 6e-16 56.9 13.1 1.4e-06 27.4 0.2 4.8 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 CAM67880.1 - 1.7e-14 53.1 10.2 1.7e-05 24.3 0.6 4.4 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.2 CAM67880.1 - 4.2e-07 29.6 2.8 0.27 10.9 0.1 3.5 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CAM67880.1 - 2.4e-06 27.5 0.0 0.0026 17.7 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Capsule_synth PF05159.9 CAM67880.1 - 0.013 15.0 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Capsule polysaccharide biosynthesis protein DUF1425 PF07233.7 CAM67880.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1425) Pkinase PF00069.20 CAM67882.2 - 2.1e-41 141.7 0.0 2.7e-41 141.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM67882.2 - 4.4e-11 42.3 0.0 6.9e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase 5_3_exonuc PF01367.15 CAM67883.1 - 3.8e-18 65.5 0.0 6.9e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold 5_3_exonuc_N PF02739.11 CAM67883.1 - 8.2e-15 54.5 0.9 4.1e-12 45.7 0.4 3.0 1 1 1 2 2 2 2 5'-3' exonuclease, N-terminal resolvase-like domain HHH_2 PF12826.2 CAM67883.1 - 0.14 12.0 0.0 0.43 10.5 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif zf-MYND PF01753.13 CAM67885.1 - 0.0012 18.6 20.3 0.002 17.9 14.1 1.4 1 0 0 1 1 1 1 MYND finger CortBP2 PF09727.4 CAM67885.1 - 0.1 12.0 0.5 0.13 11.7 0.3 1.1 1 0 0 1 1 1 0 Cortactin-binding protein-2 PUF PF00806.14 CAM67886.1 - 2.2e-51 168.5 5.1 4.4e-06 25.8 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat HNOB PF07700.10 CAM67886.1 - 0.026 14.0 0.1 2.6 7.5 0.0 3.3 2 1 2 4 4 4 0 Heme NO binding CPL PF08144.6 CAM67886.1 - 0.057 13.2 0.1 5.6 6.8 0.0 3.3 3 1 1 4 4 4 0 CPL (NUC119) domain DUF530 PF04409.7 CAM67886.1 - 0.093 10.8 0.2 0.69 7.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF530) DUF607 PF04678.8 CAM67887.1 - 4e-47 160.4 2.5 5.4e-47 160.0 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF607 Proteasome PF00227.21 CAM67888.1 - 1.2e-65 220.4 0.0 1.7e-65 219.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CAM67888.1 - 1e-09 37.5 0.7 5.5e-09 35.1 0.1 2.2 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RecA PF00154.16 CAM67888.1 - 0.012 14.7 0.0 0.17 10.9 0.0 2.4 2 1 1 3 3 3 0 recA bacterial DNA recombination protein YadA_head PF05658.9 CAM67888.1 - 1.3 9.4 4.1 4.1 7.8 0.4 2.3 2 0 0 2 2 2 0 Head domain of trimeric autotransporter adhesin Ribosomal_L32e PF01655.13 CAM67890.1 - 1.9e-40 137.2 0.5 2.3e-40 137.0 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 PAP_assoc PF03828.14 CAM67892.1 - 1.6e-05 24.7 0.3 4.6e-05 23.2 0.2 1.8 1 1 0 1 1 1 1 Cid1 family poly A polymerase SET PF00856.23 CAM67893.1 - 1.2e-07 32.1 0.4 4e-05 23.9 0.1 2.8 2 1 0 2 2 2 1 SET domain PHD PF00628.24 CAM67893.1 - 0.037 13.7 10.7 0.13 11.9 7.4 2.1 1 1 0 1 1 1 0 PHD-finger DKCLD PF08068.7 CAM67894.1 - 4.7e-28 96.8 0.0 5e-27 93.5 0.0 2.5 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 CAM67894.1 - 9.4e-23 81.0 2.5 3e-19 69.6 1.8 3.3 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 CAM67894.1 - 3e-20 71.7 0.9 5.7e-20 70.8 0.7 1.5 1 0 0 1 1 1 1 PUA domain PseudoU_synth_2 PF00849.17 CAM67894.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 RNA pseudouridylate synthase ATP-synt PF00231.14 CAM67895.1 - 1.5e-34 119.7 0.5 1.7e-34 119.4 0.3 1.1 1 0 0 1 1 1 1 ATP synthase Ribosomal_S6e PF01092.14 CAM67896.1 - 2.9e-39 133.6 0.2 5.5e-39 132.7 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e WSK PF03832.8 CAM67896.1 - 0.032 13.5 0.3 0.032 13.5 0.2 1.9 2 0 0 2 2 2 0 WSK motif RdRP_3 PF00998.18 CAM67896.1 - 0.066 11.7 6.0 0.078 11.4 4.2 1.1 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase ATP-synt_C PF00137.16 CAM67897.1 - 3.5e-25 87.6 27.0 6.2e-18 64.4 7.1 2.9 3 0 0 3 3 3 2 ATP synthase subunit C TF_Otx PF03529.8 CAM67897.1 - 0.011 15.9 0.8 0.02 15.1 0.5 1.4 1 0 0 1 1 1 0 Otx1 transcription factor GerA PF03323.8 CAM67897.1 - 0.84 7.6 5.9 1.7 6.7 0.4 2.1 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein ATP-synt_C PF00137.16 CAM67898.1 - 3.5e-25 87.6 27.0 6.2e-18 64.4 7.1 2.9 3 0 0 3 3 3 2 ATP synthase subunit C TF_Otx PF03529.8 CAM67898.1 - 0.011 15.9 0.8 0.02 15.1 0.5 1.4 1 0 0 1 1 1 0 Otx1 transcription factor GerA PF03323.8 CAM67898.1 - 0.84 7.6 5.9 1.7 6.7 0.4 2.1 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein Gaa1 PF04114.9 CAM67899.1 - 2.1e-07 30.0 1.4 2.7e-07 29.6 0.1 1.6 1 1 1 2 2 2 1 Gaa1-like, GPI transamidase component Ribosomal_L37ae PF01780.14 CAM67900.1 - 2e-36 123.7 5.1 2.1e-36 123.6 3.6 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family C1_1 PF00130.17 CAM67900.1 - 0.00075 19.1 2.1 0.0011 18.6 1.4 1.2 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) A2L_zn_ribbon PF08792.5 CAM67900.1 - 0.024 14.1 1.2 1.9 8.0 0.0 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain UPF0547 PF10571.4 CAM67900.1 - 0.046 13.4 1.1 7.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 NOB1_Zn_bind PF08772.6 CAM67900.1 - 0.089 12.6 3.7 0.98 9.2 2.6 2.3 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Carla_C4 PF01623.12 CAM67900.1 - 0.094 12.4 1.6 0.12 12.1 1.1 1.3 1 1 0 1 1 1 0 Carlavirus putative nucleic acid binding protein Zn_Tnp_IS1595 PF12760.2 CAM67900.1 - 0.12 12.2 2.5 0.18 11.6 1.7 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-C4_ClpX PF06689.8 CAM67900.1 - 6.6 6.3 7.0 1.2 8.7 2.1 1.8 2 0 0 2 2 2 0 ClpX C4-type zinc finger Proteasome PF00227.21 CAM67901.1 - 1.5e-57 193.9 0.0 2e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CAM67901.1 - 2.5e-13 49.0 0.0 7.2e-13 47.5 0.0 1.9 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Pex14_N PF04695.8 CAM67902.2 - 5.1e-31 107.5 0.2 5.1e-31 107.5 0.1 3.2 2 1 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Rootletin PF15035.1 CAM67902.2 - 7.5e-05 22.7 0.9 7.5e-05 22.7 0.6 1.5 2 0 0 2 2 1 1 Ciliary rootlet component, centrosome cohesion IncA PF04156.9 CAM67902.2 - 0.00053 19.6 0.2 0.00091 18.8 0.1 1.3 1 0 0 1 1 1 1 IncA protein DUF4398 PF14346.1 CAM67902.2 - 0.00067 19.6 3.4 0.00067 19.6 2.4 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4398) ATG16 PF08614.6 CAM67902.2 - 0.0016 18.2 0.2 0.0029 17.4 0.1 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) GAS PF13851.1 CAM67902.2 - 0.0019 17.4 2.9 0.0028 16.8 2.0 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding LOH1CR12 PF10158.4 CAM67902.2 - 0.0063 16.3 0.2 0.011 15.5 0.2 1.3 1 0 0 1 1 1 1 Tumour suppressor protein ALIX_LYPXL_bnd PF13949.1 CAM67902.2 - 0.0089 15.0 1.7 0.018 14.0 1.2 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Macoilin PF09726.4 CAM67902.2 - 0.012 13.9 0.1 0.014 13.6 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein Cast PF10174.4 CAM67902.2 - 0.039 12.0 4.7 0.054 11.5 3.2 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone HlyD_2 PF12700.2 CAM67902.2 - 0.055 12.6 0.8 0.08 12.0 0.6 1.2 1 0 0 1 1 1 0 HlyD family secretion protein CALCOCO1 PF07888.6 CAM67902.2 - 0.061 11.6 2.9 0.089 11.0 2.0 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2968 PF11180.3 CAM67902.2 - 0.095 12.0 5.3 0.23 10.8 3.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) TMCO5 PF14992.1 CAM67902.2 - 0.099 11.7 2.7 0.15 11.1 1.9 1.1 1 0 0 1 1 1 0 TMCO5 family DUF342 PF03961.8 CAM67902.2 - 0.12 10.7 1.4 0.17 10.2 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1664 PF07889.7 CAM67902.2 - 0.13 12.0 0.7 0.24 11.1 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) G-gamma PF00631.17 CAM67902.2 - 0.22 11.2 3.8 0.62 9.8 0.1 2.5 2 0 0 2 2 2 0 GGL domain Cep57_CLD_2 PF14197.1 CAM67902.2 - 0.25 11.3 6.6 3.1 7.8 0.8 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 FlxA PF14282.1 CAM67902.2 - 0.25 11.3 5.8 1.1 9.2 4.0 2.0 1 1 0 1 1 1 0 FlxA-like protein AAA_13 PF13166.1 CAM67902.2 - 0.25 9.7 2.3 0.35 9.2 1.6 1.1 1 0 0 1 1 1 0 AAA domain Syntaxin PF00804.20 CAM67902.2 - 0.26 11.4 2.6 0.52 10.4 1.8 1.4 1 0 0 1 1 1 0 Syntaxin ERM PF00769.14 CAM67902.2 - 0.28 10.6 7.0 0.53 9.7 4.9 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family TMF_DNA_bd PF12329.3 CAM67902.2 - 0.3 10.9 10.1 0.32 10.8 1.0 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Siah-Interact_N PF09032.6 CAM67902.2 - 0.31 11.1 5.6 0.62 10.1 0.2 2.6 1 1 1 2 2 2 0 Siah interacting protein, N terminal APG6 PF04111.7 CAM67902.2 - 0.41 9.6 4.0 0.64 9.0 2.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 HALZ PF02183.13 CAM67902.2 - 0.43 10.3 4.5 4.5 7.0 0.2 2.5 2 1 0 2 2 2 0 Homeobox associated leucine zipper LCD1 PF09798.4 CAM67902.2 - 0.47 8.3 0.8 0.65 7.9 0.6 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein Mnd1 PF03962.10 CAM67902.2 - 0.58 9.7 5.7 0.9 9.1 4.0 1.2 1 0 0 1 1 1 0 Mnd1 family CENP-F_leu_zip PF10473.4 CAM67902.2 - 1 9.2 7.6 0.39 10.5 0.7 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4200 PF13863.1 CAM67902.2 - 1.1 9.2 7.5 2.1 8.2 5.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) ADIP PF11559.3 CAM67902.2 - 1.6 8.6 8.2 4.9 7.0 5.6 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DivIVA PF05103.8 CAM67902.2 - 2.5 8.1 7.1 4.7 7.2 0.5 2.3 1 1 1 2 2 2 0 DivIVA protein DUF972 PF06156.8 CAM67902.2 - 3.2 8.1 4.3 21 5.4 3.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF1192 PF06698.6 CAM67902.2 - 4.1 7.2 8.3 13 5.6 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) DivIC PF04977.10 CAM67902.2 - 4.1 6.9 9.1 0.58 9.6 1.6 2.2 1 1 1 2 2 2 0 Septum formation initiator DUF3584 PF12128.3 CAM67902.2 - 6.8 3.8 7.9 9.3 3.4 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) BolA PF01722.13 CAM67904.1 - 5.9e-19 67.7 0.0 6.7e-19 67.6 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein Tubulin PF00091.20 CAM67905.1 - 7.4e-70 235.1 0.0 1.2e-69 234.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CAM67905.1 - 3.7e-48 162.7 0.0 5.6e-48 162.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CAM67905.1 - 2.7e-05 24.1 0.0 6.1e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CAM67905.1 - 0.0076 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Nodulin-like PF06813.8 CAM67906.1 - 0.00031 20.0 10.0 0.00031 20.0 7.0 2.9 3 1 0 3 3 3 1 Nodulin-like MFS_1 PF07690.11 CAM67906.1 - 0.28 9.8 53.4 0.0081 14.9 20.5 3.2 2 1 1 3 3 3 0 Major Facilitator Superfamily F-box-like PF12937.2 CAM67907.1 - 9.9e-08 31.5 0.5 2.4e-07 30.3 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CAM67907.1 - 9.2e-07 28.3 0.7 3e-06 26.7 0.3 2.1 2 0 0 2 2 2 1 F-box domain Calpain_III PF01067.17 CAM67919.2 - 6.6e-22 77.7 0.0 2.7e-07 30.3 0.0 4.0 3 2 0 3 3 3 3 Calpain large subunit, domain III LRR_6 PF13516.1 CAM67919.2 - 0.099 12.7 0.0 69 3.9 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich repeat UPF0542 PF15086.1 CAM67922.1 - 0.092 12.4 1.7 0.2 11.3 1.2 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 DUF3043 PF11241.3 CAM67922.1 - 0.18 11.3 1.3 0.19 11.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) Sigma_reg_N PF13800.1 CAM67922.1 - 1 9.4 6.7 1.2 9.1 0.1 2.6 2 1 1 3 3 3 0 Sigma factor regulator N-terminal DUF2427 PF10348.4 CAM67922.1 - 2 8.0 6.6 0.23 11.0 0.4 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) WD40 PF00400.27 CAM67925.1 - 5.1e-29 99.0 9.6 7.7e-12 44.6 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 CAM67925.1 - 0.0041 15.3 5.6 0.085 10.9 0.1 3.3 2 1 1 3 3 3 3 Nucleoporin Nup120/160 SNARE PF05739.14 CAM67927.1 - 7.4e-08 31.9 1.6 7.4e-08 31.9 1.1 2.5 3 0 0 3 3 3 1 SNARE domain Syntaxin-6_N PF09177.6 CAM67927.1 - 0.0034 17.7 3.2 0.0043 17.4 0.3 2.2 2 0 0 2 2 2 1 Syntaxin 6, N-terminal TrpBP PF02081.10 CAM67927.1 - 0.032 13.6 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein CARD PF00619.16 CAM67927.1 - 0.076 12.8 2.6 15 5.4 0.2 3.4 3 0 0 3 3 3 0 Caspase recruitment domain DUF1664 PF07889.7 CAM67927.1 - 7.6 6.3 7.8 8.8 6.1 0.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) BAR PF03114.13 CAM67928.1 - 2.1e-06 27.4 4.1 2.9e-06 26.9 2.8 1.1 1 0 0 1 1 1 1 BAR domain Gln-synt_C PF00120.19 CAM67928.1 - 0.0059 15.7 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain DUF812 PF05667.6 CAM67928.1 - 0.014 13.9 1.7 0.11 10.9 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF812) CCDC155 PF14662.1 CAM67928.1 - 0.016 14.7 3.6 0.22 11.1 0.5 2.3 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 OmpH PF03938.9 CAM67928.1 - 0.034 14.0 0.2 0.074 12.9 0.0 1.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) FH2 PF02181.18 CAM67928.1 - 0.068 12.0 4.6 1.1 8.1 0.1 2.6 2 1 1 3 3 3 0 Formin Homology 2 Domain DUF3546 PF12066.3 CAM67928.1 - 0.1 12.6 3.7 0.13 12.3 1.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3546) Orbi_VP5 PF00901.12 CAM67928.1 - 0.19 9.9 2.9 1 7.4 0.2 2.1 2 0 0 2 2 2 0 Orbivirus outer capsid protein VP5 ALIX_LYPXL_bnd PF13949.1 CAM67929.1 - 0.0013 17.7 5.9 0.0026 16.7 4.1 1.5 1 1 0 1 1 1 1 ALIX V-shaped domain binding to HIV Rab5-bind PF09311.6 CAM67929.1 - 0.0023 17.8 3.7 0.5 10.2 0.2 2.1 1 1 1 2 2 2 2 Rabaptin-like protein Rootletin PF15035.1 CAM67929.1 - 0.038 13.9 8.7 6.4 6.7 6.0 2.9 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion UPF0147 PF03685.8 CAM67929.1 - 0.063 13.1 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) Nnf1 PF03980.9 CAM67929.1 - 0.12 12.4 1.5 0.45 10.5 1.1 2.2 1 1 0 1 1 1 0 Nnf1 DUF4404 PF14357.1 CAM67929.1 - 0.14 12.5 0.7 3.6 8.0 0.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4404) DUF489 PF04356.7 CAM67929.1 - 0.25 10.8 1.9 0.56 9.7 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF489) IncA PF04156.9 CAM67929.1 - 0.61 9.6 7.7 1.5 8.3 3.4 2.3 2 1 0 2 2 2 0 IncA protein Atg14 PF10186.4 CAM67929.1 - 1 8.2 7.5 3.9 6.3 5.0 1.9 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Snapin_Pallidin PF14712.1 CAM67929.1 - 2.9 8.2 6.6 6 7.2 0.1 3.1 3 2 0 3 3 3 0 Snapin/Pallidin GrpE PF01025.14 CAM67929.1 - 3.6 7.1 11.0 78 2.7 5.7 3.0 1 1 1 2 2 2 0 GrpE zf-rbx1 PF12678.2 CAM67931.1 - 2.8e-34 117.0 15.1 3.3e-34 116.8 10.5 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CAM67931.1 - 2.6e-17 62.4 11.5 3.1e-17 62.1 8.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 CAM67931.1 - 5.2e-07 29.3 16.1 6.7e-06 25.8 11.1 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CAM67931.1 - 0.00078 19.0 13.4 0.33 10.6 9.8 2.3 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CAM67931.1 - 0.0073 15.9 14.4 0.086 12.5 10.0 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAM67931.1 - 0.11 12.5 15.6 2 8.5 10.9 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Bacteriocin_II PF01721.13 CAM67931.1 - 0.14 11.6 2.3 0.25 10.8 1.6 1.4 1 0 0 1 1 1 0 Class II bacteriocin zf-RING_5 PF14634.1 CAM67931.1 - 0.7 9.6 14.9 9.8 5.9 10.4 2.3 1 1 1 2 2 2 0 zinc-RING finger domain zf-HC5HC2H PF13771.1 CAM67931.1 - 0.87 9.7 12.1 79 3.5 8.1 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 CAM67931.1 - 1.3 9.1 12.0 4.7 7.2 8.2 1.9 1 1 0 1 1 1 0 PHD-zinc-finger like domain FANCL_C PF11793.3 CAM67931.1 - 5.5 7.0 13.5 38 4.3 9.4 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.6 CAM67931.1 - 7.3 6.6 14.7 58 3.8 10.2 2.3 1 1 0 1 1 1 0 RING-like domain Methyltransf_12 PF08242.7 CAM67932.1 - 2.3e-15 56.8 0.1 6.5e-14 52.2 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAM67932.1 - 7e-13 48.6 0.0 1e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAM67932.1 - 3e-12 47.0 0.0 2.7e-11 44.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAM67932.1 - 6.9e-12 45.2 0.1 5.3e-05 22.8 0.0 2.4 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 CAM67932.1 - 9.8e-11 42.0 0.0 1.9e-08 34.6 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAM67932.1 - 4.2e-06 27.0 0.0 1.3e-05 25.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CAM67932.1 - 1.6e-05 24.9 0.0 3.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 CAM67932.1 - 0.0022 17.4 0.1 0.0054 16.1 0.0 1.6 2 0 0 2 2 2 1 Nodulation protein S (NodS) DUF4020 PF13212.1 CAM67932.1 - 0.018 14.6 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4020) Methyltransf_24 PF13578.1 CAM67932.1 - 0.036 14.8 0.0 0.092 13.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain DUF3419 PF11899.3 CAM67932.1 - 0.045 12.4 0.0 0.1 11.3 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3419) Histone PF00125.19 CAM67933.1 - 3.7e-14 52.5 0.8 4.5e-14 52.3 0.6 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CAM67933.1 - 2.6e-05 24.1 0.1 4.3e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 CAM67933.1 - 7.4e-05 22.6 0.1 0.00011 22.0 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.8 CAM67933.1 - 0.00064 19.4 0.0 0.00081 19.0 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 CAM67933.1 - 0.0013 18.5 0.0 0.0014 18.4 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit PCP_red PF08369.5 CAM67933.1 - 0.033 14.0 1.0 0.064 13.1 0.3 1.9 2 1 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit FbpA PF05833.6 CAM67933.1 - 0.049 12.1 0.0 0.057 11.9 0.0 1.0 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF4400 PF14348.1 CAM67933.1 - 0.092 12.1 0.3 0.13 11.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) Galactosyl_T PF01762.16 CAM67934.1 - 0.00019 21.0 0.0 0.0007 19.2 0.0 1.9 2 0 0 2 2 2 1 Galactosyltransferase MIP-T3 PF10243.4 CAM67935.2 - 3.9e-109 365.5 39.4 4.4e-71 239.9 22.2 2.1 1 1 1 2 2 2 2 Microtubule-binding protein MIP-T3 Reo_sigmaC PF04582.7 CAM67935.2 - 0.18 10.9 1.3 0.3 10.2 0.9 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Pkinase PF00069.20 CAM67936.1 - 2.4e-68 230.1 0.0 5.3e-68 228.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM67936.1 - 7.6e-45 152.9 0.0 1.3e-44 152.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM67936.1 - 2.5e-07 29.9 1.0 3.3e-06 26.2 0.0 2.5 2 0 0 2 2 2 1 Kinase-like GMC_oxred_C PF05199.8 CAM67937.2 - 6.7e-13 49.1 0.1 7.8e-12 45.7 0.0 2.4 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.14 CAM67937.2 - 1.5e-11 43.9 0.0 2.1e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 CAM67937.2 - 2.2e-05 23.5 0.4 0.0027 16.6 0.0 3.2 4 0 0 4 4 4 1 Lycopene cyclase protein DAO PF01266.19 CAM67937.2 - 3.5e-05 22.8 3.5 0.00054 18.9 0.0 2.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CAM67937.2 - 0.0027 17.7 2.9 0.0057 16.6 0.2 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 CAM67937.2 - 0.0035 15.8 0.3 0.0053 15.2 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 CAM67937.2 - 0.0058 15.7 0.5 0.0058 15.7 0.3 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 CAM67937.2 - 0.0058 15.5 0.1 0.013 14.3 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 CAM67937.2 - 0.0088 15.9 0.0 0.026 14.4 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase RCR PF12273.3 CAM67938.1 - 0.0015 19.0 3.2 0.057 13.9 0.1 2.6 2 0 0 2 2 2 2 Chitin synthesis regulation, resistance to Congo red KCNQC3-Ank-G_bd PF11956.3 CAM67938.1 - 0.037 14.0 0.9 0.078 13.0 0.5 1.6 1 1 0 1 1 1 0 Ankyrin-G binding motif of KCNQ2-3 Peptidase_M24 PF00557.19 CAM67939.1 - 1.3e-43 148.9 0.1 2.1e-43 148.3 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Pol_alpha_B_N PF08418.5 CAM67939.1 - 2.4 7.6 5.6 3.5 7.0 3.9 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF4186 PF13811.1 CAM67941.1 - 0.035 13.7 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4186) MtrG PF04210.8 CAM67943.2 - 0.024 14.3 6.1 4.4e+02 0.6 0.0 8.5 10 0 0 10 10 10 0 Tetrahydromethanopterin S-methyltransferase, subunit G Tup_N PF08581.5 CAM67955.1 - 3.5e-05 23.9 10.0 0.00036 20.6 0.6 2.2 1 1 1 2 2 2 1 Tup N-terminal AKNA PF12443.3 CAM67955.1 - 0.0021 18.0 6.6 0.003 17.5 4.6 1.3 1 0 0 1 1 1 1 AT-hook-containing transcription factor IncA PF04156.9 CAM67955.1 - 0.0046 16.5 14.2 0.0075 15.8 9.1 1.7 1 1 0 1 1 1 1 IncA protein Spc7 PF08317.6 CAM67955.1 - 0.0076 14.9 12.6 0.0086 14.7 8.7 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein CENP-Q PF13094.1 CAM67955.1 - 0.0078 16.2 13.1 0.0096 15.9 9.1 1.2 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Med20 PF08612.6 CAM67955.1 - 0.013 14.6 0.3 0.016 14.4 0.2 1.2 1 0 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Uso1_p115_C PF04871.8 CAM67955.1 - 0.014 15.2 11.2 0.018 14.9 7.7 1.1 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3584 PF12128.3 CAM67955.1 - 0.023 12.0 11.0 0.028 11.7 7.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Atg14 PF10186.4 CAM67955.1 - 0.031 13.2 13.2 0.035 13.0 9.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TBPIP PF07106.8 CAM67955.1 - 0.036 13.6 11.7 0.042 13.4 8.1 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1664 PF07889.7 CAM67955.1 - 0.049 13.4 3.9 0.063 13.0 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Cluap1 PF10234.4 CAM67955.1 - 0.05 12.8 13.1 0.34 10.0 9.1 1.8 1 1 0 1 1 1 0 Clusterin-associated protein-1 DUF948 PF06103.6 CAM67955.1 - 0.057 13.2 4.0 1.8 8.4 3.1 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) IFT57 PF10498.4 CAM67955.1 - 0.059 12.0 10.4 0.079 11.6 7.2 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 FlxA PF14282.1 CAM67955.1 - 0.061 13.2 11.4 0.078 12.9 7.9 1.1 1 0 0 1 1 1 0 FlxA-like protein Nucleic_acid_bd PF13820.1 CAM67955.1 - 0.072 12.6 1.5 3.1 7.3 0.1 2.1 2 0 0 2 2 2 0 Putative nucleic acid-binding region FlaC_arch PF05377.6 CAM67955.1 - 0.075 12.9 6.3 2 8.4 1.5 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Bacillus_HBL PF05791.6 CAM67955.1 - 0.086 12.2 4.8 0.1 11.9 3.4 1.1 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF4337 PF14235.1 CAM67955.1 - 0.094 12.5 11.2 1.8 8.3 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Snapin_Pallidin PF14712.1 CAM67955.1 - 0.11 12.7 8.5 0.16 12.3 5.7 1.4 1 1 0 1 1 1 0 Snapin/Pallidin eIF3_subunit PF08597.5 CAM67955.1 - 0.21 11.0 8.4 0.25 10.8 5.8 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Allexi_40kDa PF05549.6 CAM67955.1 - 0.26 10.5 4.5 0.3 10.3 3.1 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein GvpK PF05121.7 CAM67955.1 - 0.3 10.9 6.2 0.13 12.1 0.4 2.1 1 1 1 2 2 2 0 Gas vesicle protein K WXG100 PF06013.7 CAM67955.1 - 0.3 11.0 6.2 1.3 9.0 0.7 2.3 1 1 1 2 2 2 0 Proteins of 100 residues with WXG DUF2491 PF10679.4 CAM67955.1 - 0.31 10.0 2.9 0.33 9.9 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) DivIC PF04977.10 CAM67955.1 - 0.34 10.4 12.7 0.44 10.0 3.8 2.2 1 1 1 2 2 2 0 Septum formation initiator HAUS-augmin3 PF14932.1 CAM67955.1 - 0.34 10.0 10.4 0.45 9.6 7.2 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Spc24 PF08286.6 CAM67955.1 - 0.35 10.5 13.4 0.77 9.4 5.2 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 CALCOCO1 PF07888.6 CAM67955.1 - 0.36 9.0 11.4 0.46 8.7 7.9 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4200 PF13863.1 CAM67955.1 - 0.43 10.5 17.2 0.57 10.1 11.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Mod_r PF07200.8 CAM67955.1 - 0.44 10.4 13.0 3.2 7.6 4.3 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TPR_MLP1_2 PF07926.7 CAM67955.1 - 0.52 10.0 16.0 0.29 10.8 3.2 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DivIVA PF05103.8 CAM67955.1 - 0.53 10.3 11.5 0.67 10.0 8.0 1.1 1 0 0 1 1 1 0 DivIVA protein DUF87 PF01935.12 CAM67955.1 - 0.79 9.4 4.1 0.93 9.2 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF87 APG6 PF04111.7 CAM67955.1 - 0.92 8.4 12.7 1.2 8.1 8.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 CAM67955.1 - 0.96 7.7 8.9 1 7.7 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1515 PF07439.6 CAM67955.1 - 0.97 9.2 4.7 1.8 8.3 2.7 1.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1515) Lectin_N PF03954.9 CAM67955.1 - 0.98 8.8 4.1 0.71 9.2 1.2 1.8 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF972 PF06156.8 CAM67955.1 - 1 9.7 11.6 1.8 8.9 1.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF4407 PF14362.1 CAM67955.1 - 1.2 8.0 5.8 1.6 7.5 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HAUS6_N PF14661.1 CAM67955.1 - 1.3 8.3 12.2 1.1 8.5 1.3 1.7 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF4239 PF14023.1 CAM67955.1 - 1.3 8.2 3.5 1.7 7.9 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) COG2 PF06148.6 CAM67955.1 - 1.4 8.8 7.8 1.2 8.9 2.5 1.9 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Prominin PF05478.6 CAM67955.1 - 1.4 6.3 4.8 2.1 5.7 3.2 1.3 1 1 0 1 1 1 0 Prominin Nup54 PF13874.1 CAM67955.1 - 1.8 8.2 13.4 0.53 9.9 0.6 2.0 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Seryl_tRNA_N PF02403.17 CAM67955.1 - 2.1 8.3 12.0 3.9 7.5 6.4 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain UPF0449 PF15136.1 CAM67955.1 - 2.7 8.2 9.2 12 6.2 0.1 2.2 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 FliD_N PF02465.13 CAM67955.1 - 2.8 8.3 5.7 17 5.8 0.2 2.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Remorin_C PF03763.8 CAM67955.1 - 2.8 7.5 14.7 2.5 7.6 9.5 1.4 1 1 0 1 1 1 0 Remorin, C-terminal region TMPIT PF07851.8 CAM67955.1 - 3.3 6.6 9.0 3.8 6.4 6.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein V_ATPase_I PF01496.14 CAM67955.1 - 3.6 5.3 8.5 3.8 5.2 5.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ly49 PF08391.5 CAM67955.1 - 3.8 7.6 6.3 5.2 7.2 4.3 1.4 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region Folliculin PF11704.3 CAM67955.1 - 5 6.6 7.1 64 3.0 4.9 2.0 1 1 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport H-kinase_dim PF02895.9 CAM67955.1 - 5.6 7.3 7.4 93 3.4 5.1 2.2 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain GrpE PF01025.14 CAM67955.1 - 6.3 6.3 14.1 96 2.4 9.8 2.0 1 1 0 1 1 1 0 GrpE DUF4047 PF13256.1 CAM67955.1 - 7.2 6.5 11.2 4.8 7.1 2.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) EMP24_GP25L PF01105.19 CAM67955.1 - 8.7 6.0 10.8 23 4.6 7.5 1.7 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD BAG PF02179.11 CAM67956.1 - 0.00034 20.6 0.1 0.00066 19.7 0.1 1.4 1 0 0 1 1 1 1 BAG domain DUF2036 PF09724.4 CAM67957.2 - 1.3e-30 106.6 0.0 2e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) zf-CCCH PF00642.19 CAM67958.1 - 1.9e-05 24.1 1.6 1.9e-05 24.1 1.1 3.7 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CAM67958.1 - 0.0084 16.0 5.9 0.66 10.0 0.2 2.9 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type LRV_FeS PF05484.6 CAM67958.1 - 0.04 13.4 5.7 0.095 12.2 0.2 2.4 2 0 0 2 2 2 0 LRV protein FeS4 cluster Apolipoprotein PF01442.13 CAM67960.1 - 1.3e-05 24.8 11.0 1.3e-05 24.8 7.6 1.7 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 CAM67960.1 - 0.00013 22.2 18.1 0.046 14.1 4.3 3.3 1 1 2 3 3 3 3 Bacterial protein of unknown function (DUF883) Baculo_PEP_C PF04513.7 CAM67960.1 - 0.021 14.6 8.1 0.072 12.9 0.2 3.0 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoO PF09769.4 CAM67960.1 - 0.032 13.9 5.1 0.076 12.7 2.3 2.4 1 1 1 2 2 2 0 Apolipoprotein O Prominin PF05478.6 CAM67960.1 - 0.055 11.0 7.8 0.12 9.9 5.4 1.5 1 1 0 1 1 1 0 Prominin DUF357 PF04010.8 CAM67960.1 - 0.07 12.8 1.7 0.51 10.0 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF357) ATP-synt_B PF00430.13 CAM67960.1 - 0.088 12.6 18.6 0.091 12.5 3.1 2.6 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Dicistro_VP4 PF11492.3 CAM67960.1 - 0.097 12.6 5.5 1.4 8.9 0.2 3.0 3 0 0 3 3 3 0 Cricket paralysis virus, VP4 ATG_C PF09333.6 CAM67960.1 - 0.14 12.3 18.4 47 4.2 10.5 4.0 1 1 1 2 2 2 0 ATG C terminal domain HisKA_3 PF07730.8 CAM67960.1 - 0.27 11.6 6.6 8.7 6.7 0.1 3.6 1 1 2 3 3 3 0 Histidine kinase RRF PF01765.14 CAM67960.1 - 0.31 10.4 9.8 9 5.7 0.2 3.2 2 1 1 3 3 3 0 Ribosome recycling factor DUF745 PF05335.8 CAM67960.1 - 0.38 10.2 30.5 0.02 14.4 16.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF745) AIP3 PF03915.8 CAM67960.1 - 0.49 9.2 8.9 0.75 8.6 6.2 1.3 1 0 0 1 1 1 0 Actin interacting protein 3 ApoLp-III PF07464.6 CAM67960.1 - 0.76 9.7 17.5 1 9.3 5.4 2.5 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF4407 PF14362.1 CAM67960.1 - 0.83 8.5 13.7 2 7.2 9.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ZYG-11_interact PF05884.7 CAM67960.1 - 0.97 8.4 8.3 26 3.7 5.7 2.2 1 1 0 1 1 1 0 Interactor of ZYG-11 Spc7 PF08317.6 CAM67960.1 - 1.1 7.8 6.4 1.7 7.2 2.6 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Syntaxin-6_N PF09177.6 CAM67960.1 - 1.3 9.4 8.6 34 4.9 4.9 3.4 2 2 0 2 2 2 0 Syntaxin 6, N-terminal DUF1451 PF07295.6 CAM67960.1 - 1.8 8.3 5.6 2.6 7.8 0.8 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1451) Mer2 PF09074.5 CAM67960.1 - 2.4 8.0 9.5 0.24 11.2 1.6 2.4 2 1 1 3 3 3 0 Mer2 PhaP_Bmeg PF09602.5 CAM67960.1 - 3.9 7.2 12.8 0.34 10.7 4.0 2.3 2 1 1 3 3 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) MCPVI PF02993.9 CAM67960.1 - 4.1 7.4 14.2 0.25 11.4 6.0 1.7 2 0 0 2 2 2 0 Minor capsid protein VI YtxH PF12732.2 CAM67960.1 - 4.7 7.6 15.8 4.2e+03 -1.9 11.0 3.8 1 1 0 1 1 1 0 YtxH-like protein DUF4398 PF14346.1 CAM67960.1 - 8.2 6.5 27.4 1.3 9.0 14.9 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4398) KfrA_N PF11740.3 CAM67960.1 - 9.6 6.6 21.1 0.59 10.5 6.6 2.8 2 1 1 3 3 3 0 Plasmid replication region DNA-binding N-term zf-C3HC4 PF00097.20 CAM67961.1 - 0.0092 15.6 20.1 0.051 13.2 13.0 2.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAM67961.1 - 0.023 14.7 17.7 0.023 14.7 12.2 2.5 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Metal_resist PF13801.1 CAM67961.1 - 0.048 13.6 0.1 0.048 13.6 0.1 2.0 2 0 0 2 2 2 0 Heavy-metal resistance zf-RING_5 PF14634.1 CAM67961.1 - 0.29 10.8 23.3 0.048 13.3 12.7 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_6 PF14835.1 CAM67961.1 - 0.4 10.5 14.6 0.99 9.2 10.1 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF1736 PF08409.6 CAM67963.2 - 5.5e-23 80.3 0.5 1.5e-22 78.9 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_11 PF13414.1 CAM67963.2 - 0.0006 19.4 7.9 0.0018 17.8 0.4 3.0 2 1 1 3 3 3 2 TPR repeat TPR_17 PF13431.1 CAM67963.2 - 0.017 15.3 1.0 1.7 9.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Aa_trans PF01490.13 CAM67964.1 - 2.7e-61 207.3 31.6 3.1e-61 207.0 21.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CAM67964.1 - 6.2e-06 25.2 11.4 6.2e-06 25.2 7.9 2.0 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family PRCC PF10253.4 CAM67965.1 - 0.013 16.2 0.2 0.013 16.2 0.2 2.5 2 1 0 3 3 3 0 Mitotic checkpoint regulator, MAD2B-interacting Y_phosphatase3 PF13350.1 CAM67966.1 - 1.1e-38 133.0 0.0 1.4e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 CAM67966.1 - 4.8e-11 42.6 0.1 1.3e-10 41.2 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 CAM67966.1 - 0.024 13.9 0.0 0.041 13.2 0.0 1.6 1 1 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.15 CAM67966.1 - 0.025 14.1 0.0 0.038 13.5 0.0 1.4 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CAM67966.1 - 0.028 13.7 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CAM67966.1 - 0.048 13.7 0.0 0.091 12.8 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate TRAP_alpha PF03896.11 CAM67967.1 - 1.9e-16 59.9 1.0 3.4e-16 59.1 0.7 1.5 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit zf-Tim10_DDP PF02953.10 CAM67968.1 - 5.9e-13 47.9 3.1 6.2e-13 47.8 2.2 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 CAM67968.1 - 0.013 14.9 1.9 0.015 14.7 1.3 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Mito_carr PF00153.22 CAM67971.1 - 8.2e-10 38.2 0.2 2.6e-07 30.2 0.0 3.3 3 0 0 3 3 3 2 Mitochondrial carrier protein Carn_acyltransf PF00755.15 CAM67973.1 - 2e-69 234.2 0.0 4.9e-69 232.9 0.0 1.6 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase SEP PF08059.8 CAM67974.1 - 9.1e-19 67.5 0.0 3e-18 65.8 0.0 1.9 2 0 0 2 2 2 1 SEP domain CUE PF02845.11 CAM67974.1 - 0.0008 18.8 0.0 0.0017 17.7 0.0 1.5 1 0 0 1 1 1 1 CUE domain UBA_4 PF14555.1 CAM67974.1 - 0.014 14.9 0.1 0.03 13.8 0.1 1.5 1 0 0 1 1 1 0 UBA-like domain SIS_2 PF13580.1 CAM67975.1 - 0.082 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 SIS domain THF_DHG_CYH_C PF02882.14 CAM67976.1 - 3e-30 104.4 0.5 1.5e-28 98.9 0.2 2.5 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 CAM67976.1 - 5.1e-29 100.6 0.0 8.4e-29 99.9 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain CDK5_activator PF03261.10 CAM67976.1 - 0.099 11.9 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Macoilin PF09726.4 CAM67977.1 - 0.065 11.5 3.8 0.079 11.2 2.6 1.0 1 0 0 1 1 1 0 Transmembrane protein Pterin_bind PF00809.17 CAM67977.1 - 0.066 12.5 0.1 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Pterin binding enzyme Nup54 PF13874.1 CAM67977.1 - 0.16 11.6 6.4 0.13 11.9 3.4 1.6 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 OPA3 PF07047.7 CAM67978.1 - 0.11 12.2 2.4 0.18 11.5 1.7 1.4 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) DUF3653 PF12375.3 CAM67978.1 - 1 9.6 4.9 0.56 10.4 1.3 2.2 2 0 0 2 2 2 0 Phage protein DHHA1 PF02272.14 CAM67978.1 - 3.1 7.5 7.7 5.6 6.7 0.6 2.8 2 0 0 2 2 2 0 DHHA1 domain DUF1663 PF07909.6 CAM67978.1 - 3.8 5.9 9.7 0.85 8.0 4.6 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1663) DUF2665 PF11654.3 CAM67979.1 - 0.091 12.3 0.0 0.51 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2665) DNA_primase_S PF01896.14 CAM67981.1 - 3.5e-39 133.9 0.1 5.3e-39 133.3 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit cNMP_binding PF00027.24 CAM67982.1 - 2.4e-05 24.0 0.0 0.0078 15.9 0.0 3.2 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain GCC2_GCC3 PF07699.8 CAM67983.1 - 2.2e-05 23.9 17.1 0.00041 19.8 3.8 9.0 6 4 3 9 9 9 5 GCC2 and GCC3 NCD3G PF07562.9 CAM67983.1 - 9 6.1 52.4 0.12 12.0 0.8 8.5 6 4 2 8 8 8 0 Nine Cysteines Domain of family 3 GPCR CK1gamma_C PF12605.3 CAM67984.2 - 2.2e-24 85.8 32.5 12 6.5 0.0 16.0 1 1 15 16 16 16 16 Casein kinase 1 gamma C terminal Y_phosphatase PF00102.22 CAM67984.2 - 4.6e-05 22.8 14.4 2.4e+02 0.8 0.0 11.8 1 1 11 15 15 15 0 Protein-tyrosine phosphatase Ribosomal_S19 PF00203.16 CAM67985.1 - 4.1e-27 93.6 0.3 6.6e-27 92.9 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 PmbA_TldD PF01523.11 CAM67985.1 - 0.0056 15.9 0.0 0.0063 15.8 0.0 1.2 1 0 0 1 1 1 1 Putative modulator of DNA gyrase FlaC_arch PF05377.6 CAM67986.2 - 0.04 13.8 0.2 0.42 10.5 0.0 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Acetyltransf_1 PF00583.19 CAM67987.1 - 3.8e-13 49.2 0.0 6.2e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CAM67987.1 - 1.8e-06 27.9 0.0 3.7e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CAM67987.1 - 0.00015 21.4 0.0 0.00032 20.4 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 CAM67987.1 - 0.00069 19.7 0.0 0.002 18.2 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CAM67987.1 - 0.031 14.1 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_S19 PF00203.16 CAM67988.1 - 4.1e-27 93.6 0.3 6.6e-27 92.9 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 PmbA_TldD PF01523.11 CAM67988.1 - 0.0056 15.9 0.0 0.0063 15.8 0.0 1.2 1 0 0 1 1 1 1 Putative modulator of DNA gyrase tRNA_bind PF01588.15 CAM67989.1 - 1.4e-25 88.9 0.1 2.9e-25 87.9 0.1 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain Med3 PF11593.3 CAM67989.1 - 3.9 6.6 9.2 9.5 5.3 6.4 1.4 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal Dynamin_N PF00350.18 CAM67990.1 - 6e-15 55.4 0.0 1.9e-14 53.8 0.0 1.8 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 CAM67990.1 - 7.9e-11 41.9 0.0 2e-10 40.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CAM67990.1 - 0.0015 17.8 0.0 0.26 10.5 0.0 2.6 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 CAM67990.1 - 0.0034 16.5 0.2 0.017 14.3 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 CAM67990.1 - 0.0072 16.8 0.0 0.45 11.0 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 CAM67990.1 - 0.018 14.4 0.1 1.2 8.5 0.0 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Nup153 PF08604.5 CAM67990.1 - 0.019 13.6 0.0 0.028 13.1 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup153-like Lysine_decarbox PF03641.9 CAM67990.1 - 0.024 14.4 0.0 0.067 13.0 0.0 1.6 1 1 0 1 1 1 0 Possible lysine decarboxylase ABC_tran PF00005.22 CAM67990.1 - 0.068 13.4 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter G-alpha PF00503.15 CAM67990.1 - 0.13 10.9 0.2 7.1 5.1 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Pkinase PF00069.20 CAM67991.1 - 1.6e-44 152.0 0.0 2.7e-36 125.0 0.0 3.8 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAM67991.1 - 2.5e-19 69.3 0.0 2.2e-16 59.6 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 CAM67991.1 - 4.7e-05 23.2 0.0 0.00013 21.8 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CAM67991.1 - 7.9e-05 21.8 0.0 0.00015 20.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CAM67991.1 - 0.18 11.3 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Med26 PF08711.6 CAM67992.2 - 2.8e-06 26.7 5.1 4.6e-05 22.8 0.0 3.2 3 0 0 3 3 3 2 TFIIS helical bundle-like domain RabGAP-TBC PF00566.13 CAM67994.1 - 2.1e-33 115.6 0.0 3.5e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF2580 PF10824.3 CAM67994.1 - 1.4 9.2 11.3 0.087 13.1 2.8 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2580) Rotamase PF00639.16 CAM67995.1 - 1.7e-13 51.1 0.0 2.8e-13 50.4 0.0 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 CAM67995.1 - 1.1e-08 35.3 0.0 1.9e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 CAM67995.1 - 3.7e-05 24.3 0.1 0.00011 22.7 0.0 1.7 2 0 0 2 2 2 1 PPIC-type PPIASE domain PPR PF01535.15 CAM67996.1 - 0.0076 16.1 0.0 15 5.8 0.0 4.2 3 0 0 3 3 3 1 PPR repeat Kinesin PF00225.18 CAM67997.1 - 3.2e-86 289.0 0.1 3.4e-47 160.7 0.0 2.5 2 0 0 2 2 2 2 Kinesin motor domain TPR_MLP1_2 PF07926.7 CAM67997.1 - 0.33 10.6 39.6 0.01 15.5 11.6 4.4 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.16 CAM67997.1 - 0.49 10.4 18.3 4.3 7.3 0.1 5.3 3 1 2 5 5 5 0 bZIP transcription factor AAA PF00004.24 CAM67998.1 - 1.3e-43 148.3 0.1 3e-43 147.1 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CAM67998.1 - 7.1e-07 29.4 0.0 0.00056 20.0 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.9 CAM67998.1 - 1.5e-06 28.0 0.1 3.2e-05 23.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CAM67998.1 - 1.7e-05 24.8 0.0 4e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CAM67998.1 - 1.8e-05 24.8 0.0 8.4e-05 22.6 0.0 1.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 CAM67998.1 - 0.0001 23.1 0.7 0.00029 21.6 0.1 2.3 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 CAM67998.1 - 0.00018 20.5 0.0 0.00033 19.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 CAM67998.1 - 0.00033 19.7 0.0 0.00064 18.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Arch_ATPase PF01637.13 CAM67998.1 - 0.00054 19.7 0.1 0.27 10.9 0.0 2.7 2 1 1 3 3 3 1 Archaeal ATPase AAA_19 PF13245.1 CAM67998.1 - 0.00069 19.3 0.1 0.0015 18.2 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 CAM67998.1 - 0.0011 18.9 0.0 0.0025 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CAM67998.1 - 0.0013 18.6 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CAM67998.1 - 0.0023 17.0 0.0 0.0043 16.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 CAM67998.1 - 0.0024 17.7 0.0 0.0047 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CAM67998.1 - 0.0028 17.0 0.0 0.005 16.2 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 CAM67998.1 - 0.0067 16.7 0.0 0.022 15.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CAM67998.1 - 0.0071 16.4 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.16 CAM67998.1 - 0.0072 15.5 0.0 0.019 14.1 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 CAM67998.1 - 0.0083 15.7 0.1 0.017 14.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 CAM67998.1 - 0.0089 15.6 0.0 0.022 14.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 CAM67998.1 - 0.0091 14.7 0.0 0.016 13.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Histone PF00125.19 CAM67998.1 - 0.018 15.1 0.1 0.085 12.9 0.0 2.2 2 0 0 2 2 1 0 Core histone H2A/H2B/H3/H4 AAA_25 PF13481.1 CAM67998.1 - 0.023 14.1 0.8 0.14 11.5 0.1 2.1 1 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 CAM67998.1 - 0.03 14.0 0.1 0.064 12.9 0.0 1.6 1 0 0 1 1 1 0 NTPase Sigma54_activat PF00158.21 CAM67998.1 - 0.049 13.1 0.0 0.14 11.5 0.0 1.8 2 0 0 2 2 1 0 Sigma-54 interaction domain PhoH PF02562.11 CAM67998.1 - 0.063 12.5 0.2 0.15 11.2 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 CAM67998.1 - 0.066 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 CAM67998.1 - 0.09 11.6 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Rer1 PF03248.8 CAM67999.1 - 2.9e-58 196.3 3.5 3.7e-58 196.0 2.4 1.0 1 0 0 1 1 1 1 Rer1 family UPF0066 PF01980.11 CAM68000.2 - 4.3e-27 94.4 0.0 1e-23 83.5 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised protein family UPF0066 PWWP PF00855.12 CAM68000.2 - 6e-05 23.1 0.6 0.00014 21.9 0.4 1.9 1 1 0 1 1 1 1 PWWP domain Acetyltransf_3 PF13302.1 CAM68001.1 - 7.8e-13 48.8 0.0 1.5e-06 28.3 0.0 2.8 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CAM68001.1 - 3e-05 23.9 0.0 5.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 CAM68001.1 - 7.4e-05 22.6 0.1 0.0018 18.1 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CAM68001.1 - 0.01 15.5 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_4 PF13420.1 CAM68001.1 - 0.044 13.7 0.0 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain UQ_con PF00179.21 CAM68002.1 - 4.2e-42 142.8 0.0 5.4e-42 142.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CAM68002.1 - 3.1e-05 23.7 0.0 4.4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CAM68002.1 - 0.012 15.5 0.0 0.016 15.1 0.0 1.4 1 1 0 1 1 1 0 RWD domain AAA PF00004.24 CAM68003.1 - 3e-38 131.0 0.3 7.9e-38 129.6 0.0 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CAM68003.1 - 1.8e-05 24.4 0.1 0.00017 21.3 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CAM68003.1 - 3.5e-05 23.8 1.5 0.0085 16.0 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 CAM68003.1 - 0.00031 20.6 0.1 0.0033 17.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 CAM68003.1 - 0.00032 19.8 0.0 0.001 18.1 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 CAM68003.1 - 0.0016 17.3 0.4 0.0034 16.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.1 CAM68003.1 - 0.0021 18.1 2.3 0.053 13.6 0.1 2.8 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.1 CAM68003.1 - 0.004 17.0 0.4 0.041 13.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CAM68003.1 - 0.0067 16.1 0.2 0.02 14.6 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 CAM68003.1 - 0.0067 15.6 0.0 0.016 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 CAM68003.1 - 0.011 14.7 1.3 0.017 14.2 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin IstB_IS21 PF01695.12 CAM68003.1 - 0.016 14.6 0.6 0.041 13.3 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.1 CAM68003.1 - 0.036 13.4 0.3 0.036 13.4 0.2 2.7 2 1 0 3 3 3 0 AAA domain KaiC PF06745.8 CAM68003.1 - 0.046 12.8 0.1 0.12 11.4 0.0 1.7 2 0 0 2 2 2 0 KaiC PhoH PF02562.11 CAM68003.1 - 0.048 12.8 0.0 0.21 10.8 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein NACHT PF05729.7 CAM68003.1 - 0.061 12.9 0.2 0.64 9.6 0.0 2.4 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.21 CAM68003.1 - 0.067 12.6 0.0 0.38 10.2 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 CAM68003.1 - 0.079 12.5 0.1 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CAM68003.1 - 0.12 13.1 3.4 0.13 13.0 0.1 2.6 2 2 0 2 2 2 0 AAA domain HeH PF12949.2 CAM68006.1 - 0.013 15.0 0.0 0.029 13.9 0.0 1.6 1 0 0 1 1 1 0 HeH/LEM domain Armet PF10208.4 CAM68006.1 - 0.046 13.3 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Degradation arginine-rich protein for mis-folding Prefoldin PF02996.12 CAM68008.1 - 5.8e-19 67.8 2.4 7.5e-19 67.5 0.9 1.6 1 1 1 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.15 CAM68008.1 - 0.0053 16.4 1.0 0.056 13.2 0.6 2.1 2 0 0 2 2 2 1 Prefoldin subunit THF_DHG_CYH_C PF02882.14 CAM68008.1 - 0.031 13.3 0.3 0.06 12.4 0.1 1.4 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain YebO PF13974.1 CAM68008.1 - 0.16 11.7 1.9 0.31 10.8 1.3 1.5 1 0 0 1 1 1 0 YebO-like protein Sec20 PF03908.8 CAM68008.1 - 0.23 11.1 2.3 13 5.6 1.4 2.4 3 0 0 3 3 3 0 Sec20 DUF1454 PF07305.7 CAM68009.1 - 0.036 13.1 0.0 0.039 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) PMG PF05287.7 CAM68011.1 - 1.7e-12 47.5 41.5 0.019 14.7 1.3 7.3 1 1 6 7 7 7 7 PMG protein YbaB_DNA_bd PF02575.11 CAM68013.1 - 2.5e-05 24.0 0.0 5.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family HIF-1 PF11413.3 CAM68013.1 - 0.017 14.2 0.0 0.034 13.3 0.0 1.4 1 0 0 1 1 1 0 Hypoxia-inducible factor-1 MMR_HSR1 PF01926.18 CAM68014.1 - 1e-15 57.7 0.0 6.3e-15 55.1 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CAM68014.1 - 8.2e-08 32.2 0.0 1.2e-05 25.1 0.0 2.4 1 1 1 2 2 2 1 Dynamin family GTP_EFTU PF00009.22 CAM68014.1 - 5.1e-06 26.0 0.0 4.2e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CAM68014.1 - 0.014 14.5 0.0 0.029 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Miro PF08477.8 CAM68014.1 - 0.017 15.5 0.0 0.08 13.4 0.0 2.1 1 1 0 1 1 1 0 Miro-like protein Septin PF00735.13 CAM68014.1 - 0.027 13.4 0.0 0.051 12.5 0.0 1.4 1 0 0 1 1 1 0 Septin cobW PF02492.14 CAM68014.1 - 0.057 12.8 0.0 0.55 9.6 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AIG1 PF04548.11 CAM68014.1 - 0.1 11.6 0.0 0.37 9.8 0.0 1.9 1 1 0 1 1 1 0 AIG1 family FeoB_N PF02421.13 CAM68014.1 - 0.15 11.3 0.0 0.44 9.8 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.22 CAM68014.1 - 0.16 12.2 0.0 0.43 10.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Pkinase PF00069.20 CAM68015.1 - 3.5e-65 219.7 0.0 4.2e-65 219.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM68015.1 - 5.5e-33 114.1 0.0 7.3e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM68015.1 - 4.1e-06 25.9 0.0 5.6e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CAM68015.1 - 0.025 13.6 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CAM68015.1 - 0.065 12.9 0.1 0.47 10.1 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF2719 PF10891.3 CAM68016.1 - 0.0097 15.5 0.1 1.7 8.3 0.0 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF2719) DUF4428 PF14471.1 CAM68016.1 - 0.019 14.6 0.1 0.066 12.9 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Mu-like_Com PF10122.4 CAM68016.1 - 0.039 12.9 16.1 0.2 10.7 0.7 4.0 2 2 1 3 3 3 0 Mu-like prophage protein Com Zn_Tnp_IS1595 PF12760.2 CAM68016.1 - 0.046 13.5 1.2 0.046 13.5 0.9 3.4 3 1 2 5 5 5 0 Transposase zinc-ribbon domain DUF2296 PF10058.4 CAM68016.1 - 0.048 13.4 0.5 0.048 13.4 0.3 3.3 2 1 2 4 4 4 0 Predicted integral membrane metal-binding protein (DUF2296) DZR PF12773.2 CAM68016.1 - 0.34 10.7 11.8 22 4.9 3.3 3.7 1 1 2 3 3 3 0 Double zinc ribbon LIM PF00412.17 CAM68016.1 - 1.5 8.9 7.4 0.86 9.7 2.6 2.4 2 1 0 2 2 2 0 LIM domain Cytochrom_c3_2 PF14537.1 CAM68016.1 - 2.5 8.5 15.3 0.64 10.3 6.3 2.4 1 1 1 2 2 2 0 Cytochrome c3 Cytochrom_CIII PF02085.11 CAM68016.1 - 9.3 6.4 13.8 6.1 6.9 6.2 2.2 1 1 1 2 2 2 0 Class III cytochrome C family SUI1 PF01253.17 CAM68017.1 - 3.4e-15 55.5 0.0 1.2e-14 53.8 0.0 2.0 2 0 0 2 2 2 1 Translation initiation factor SUI1 POT1 PF02765.12 CAM68017.1 - 0.011 15.6 0.1 0.072 12.9 0.0 2.2 2 0 0 2 2 2 0 Telomeric single stranded DNA binding POT1/CDC13 PUA PF01472.15 CAM68017.1 - 0.044 13.5 0.1 0.16 11.7 0.0 2.0 1 0 0 1 1 1 0 PUA domain NAD_binding_1 PF00175.16 CAM68018.1 - 5.2e-25 88.1 0.0 7.7e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CAM68018.1 - 2.1e-19 69.4 0.0 3.1e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 CAM68018.1 - 9.7e-07 28.8 0.0 5.5e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 CAM68019.1 - 7.1e-24 83.8 0.0 1.2e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 CAM68019.1 - 1.6e-22 80.0 0.0 2.4e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 CAM68019.1 - 0.00014 21.7 0.0 0.00027 20.8 0.0 1.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain zf-CCCH PF00642.19 CAM68021.1 - 0.00098 18.7 1.0 0.00098 18.7 0.7 3.6 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF3184 PF11380.3 CAM68024.1 - 1.2e-89 301.0 25.8 6.8e-50 169.7 6.8 5.0 2 2 1 3 3 3 3 Protein of unknown function (DUF3184) Ribosomal_L22 PF00237.14 CAM68025.1 - 8.4e-13 48.1 0.0 1.2e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e IQ PF00612.22 CAM68028.1 - 0.019 14.5 2.4 0.055 13.1 1.7 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif Prp18 PF02840.10 CAM68029.1 - 3.6e-10 39.8 0.2 3.6e-10 39.8 0.1 1.9 3 0 0 3 3 3 1 Prp18 domain EF-hand_7 PF13499.1 CAM68030.1 - 7.1e-13 48.4 0.1 4e-06 26.8 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 CAM68030.1 - 1.7e-12 46.0 1.1 0.1 12.5 0.0 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.27 CAM68030.1 - 1.6e-08 33.2 0.0 0.44 9.9 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 CAM68030.1 - 2.2e-07 30.3 0.1 0.16 11.6 0.0 4.2 5 0 0 5 5 5 2 EF-hand domain pair Cbl_N2 PF02761.9 CAM68030.1 - 0.041 13.9 0.5 4.1 7.5 0.1 3.0 3 0 0 3 3 3 0 CBL proto-oncogene N-terminus, EF hand-like domain AAA PF00004.24 CAM68031.1 - 3.6e-13 49.8 0.0 2.5e-07 30.9 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CAM68031.1 - 5.3e-05 22.9 0.0 0.00011 21.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CAM68031.1 - 0.035 14.9 0.0 0.084 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CAM68031.1 - 0.083 12.8 0.3 0.33 10.9 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain HupE_UreJ PF04955.7 CAM68031.1 - 0.78 9.0 6.3 0.086 12.1 0.5 2.0 2 0 0 2 2 2 0 HupE / UreJ protein Pkinase PF00069.20 CAM68032.1 - 2.5e-62 210.3 0.0 3e-62 210.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM68032.1 - 1.1e-42 145.9 0.0 1.3e-42 145.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM68032.1 - 2.6e-08 33.1 0.0 3.7e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CAM68032.1 - 0.092 11.7 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinesin PF00225.18 CAM68033.1 - 2.3e-88 296.0 0.2 7.6e-88 294.4 0.1 1.9 1 0 0 1 1 1 1 Kinesin motor domain WD40 PF00400.27 CAM68035.2 - 0.00084 19.1 0.0 0.013 15.3 0.0 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat UAA PF08449.6 CAM68038.1 - 3.4e-43 147.7 16.7 6.4e-25 87.6 1.3 3.0 3 0 0 3 3 3 3 UAA transporter family Kelch_4 PF13418.1 CAM68040.1 - 2.4e-20 72.0 18.2 1.4e-05 24.7 0.4 7.1 5 2 1 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 CAM68040.1 - 2.5e-17 62.4 9.2 9e-05 22.3 0.2 7.2 6 1 0 6 6 6 3 Kelch motif Kelch_3 PF13415.1 CAM68040.1 - 4.6e-17 61.6 25.4 7e-05 22.8 0.0 8.4 8 1 0 8 8 8 4 Galactose oxidase, central domain Kelch_6 PF13964.1 CAM68040.1 - 1.5e-15 56.5 5.9 0.0011 19.0 0.1 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.20 CAM68040.1 - 5.3e-14 51.4 9.6 0.00067 19.1 0.1 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 CAM68040.1 - 9.4e-06 25.1 13.3 0.0025 17.5 0.2 5.8 6 1 0 6 6 6 2 Kelch motif BTB PF00651.26 CAM68040.1 - 4.4e-05 23.4 0.1 0.0032 17.4 0.0 3.4 4 0 0 4 4 4 1 BTB/POZ domain CheY-binding PF09078.6 CAM68040.1 - 0.024 14.6 0.2 1.9 8.5 0.0 2.5 2 0 0 2 2 2 0 CheY binding FG-GAP PF01839.18 CAM68041.1 - 0.046 13.4 0.3 0.11 12.2 0.2 1.6 1 0 0 1 1 1 0 FG-GAP repeat MFS_1 PF07690.11 CAM68042.1 - 1.6e-23 83.0 25.5 1.6e-23 83.0 17.7 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CAM68042.1 - 7e-16 57.8 3.8 7e-16 57.8 2.6 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 CAM68042.1 - 1.2e-13 50.0 11.4 7.4e-08 30.8 0.5 3.9 2 2 2 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family LSM PF01423.17 CAM68043.1 - 4e-13 48.7 0.1 5.2e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain Med20 PF08612.6 CAM68043.1 - 0.064 12.3 0.0 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex DUF3247 PF11607.3 CAM68043.1 - 0.093 12.9 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3247) DUF2782 PF11191.3 CAM68043.1 - 0.12 12.3 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) CRAL_TRIO PF00650.15 CAM68046.1 - 3.1e-13 49.5 0.0 1.3e-12 47.5 0.0 1.9 1 1 0 1 1 1 1 CRAL/TRIO domain DHC_N2 PF08393.8 CAM68048.2 - 1.6e-88 296.9 0.0 1.1e-87 294.2 0.0 2.3 3 0 0 3 3 2 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 CAM68048.2 - 3.8e-86 289.6 0.0 2.3e-85 287.1 0.0 2.3 1 1 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 CAM68048.2 - 7.4e-82 274.3 0.0 3.7e-81 272.0 0.0 2.3 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 CAM68048.2 - 1e-38 132.4 0.0 1.9e-38 131.5 0.0 1.4 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 CAM68048.2 - 1.3e-36 126.1 2.4 2.1e-36 125.3 1.7 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_8 PF12780.2 CAM68048.2 - 2.1e-34 118.7 0.1 2.2e-25 89.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region D4 AAA_5 PF07728.9 CAM68048.2 - 3.6e-31 107.7 0.0 5.3e-11 42.4 0.0 6.2 4 2 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA PF00004.24 CAM68048.2 - 1.6e-19 70.4 0.2 3.7e-06 27.1 0.0 5.1 5 0 0 5 5 4 4 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.2 CAM68048.2 - 2.5e-19 69.4 0.0 1.6e-18 66.8 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 CAM68048.2 - 1.6e-13 50.9 8.5 1.8e-05 24.9 0.0 6.7 8 0 0 8 8 4 3 AAA domain AAA_16 PF13191.1 CAM68048.2 - 8.9e-13 48.6 11.3 0.023 14.6 0.0 7.7 7 0 0 7 7 5 4 AAA ATPase domain AAA_17 PF13207.1 CAM68048.2 - 1.2e-09 39.0 0.0 0.39 11.5 0.0 5.4 4 0 0 4 4 4 2 AAA domain FtsK_SpoIIIE PF01580.13 CAM68048.2 - 7.7e-08 32.0 0.4 0.017 14.5 0.0 4.2 4 0 0 4 4 3 2 FtsK/SpoIIIE family AAA_18 PF13238.1 CAM68048.2 - 6.2e-07 29.7 0.0 0.71 10.1 0.0 5.1 5 0 0 5 5 4 1 AAA domain AAA_33 PF13671.1 CAM68048.2 - 8.5e-07 28.9 3.4 0.22 11.3 0.0 4.9 5 0 0 5 5 4 2 AAA domain AAA_14 PF13173.1 CAM68048.2 - 1.1e-05 25.3 0.0 3.5 7.5 0.0 4.9 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.17 CAM68048.2 - 0.00023 21.3 0.2 3.7 7.7 0.0 4.5 4 0 0 4 4 4 1 RNA helicase DUF258 PF03193.11 CAM68048.2 - 0.00039 19.6 0.3 7.9 5.6 0.0 3.8 3 0 0 3 3 3 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 CAM68048.2 - 0.00039 19.9 1.4 6.5 6.1 0.0 4.8 4 1 0 4 4 4 0 AAA-like domain Sigma54_activat PF00158.21 CAM68048.2 - 0.00052 19.5 0.0 0.4 10.1 0.0 3.4 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_29 PF13555.1 CAM68048.2 - 0.0007 19.0 0.9 2 8.0 0.0 4.2 4 0 0 4 4 3 1 P-loop containing region of AAA domain Mg_chelatase PF01078.16 CAM68048.2 - 0.0018 17.4 6.1 0.19 10.8 0.0 3.8 4 0 0 4 4 3 2 Magnesium chelatase, subunit ChlI DHC_N1 PF08385.7 CAM68048.2 - 0.0044 15.4 0.1 0.0044 15.4 0.1 4.8 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 1 MobB PF03205.9 CAM68048.2 - 0.016 14.9 1.5 1.5 8.5 0.0 4.0 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 CAM68048.2 - 0.058 13.2 0.1 17 5.1 0.0 3.8 3 0 0 3 3 3 0 Domain of unknown function DUF87 ResIII PF04851.10 CAM68048.2 - 0.094 12.5 0.1 13 5.5 0.0 3.5 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.10 CAM68048.2 - 0.12 12.0 1.4 85 2.7 0.0 4.1 4 0 0 4 4 4 0 NTPase Arch_ATPase PF01637.13 CAM68048.2 - 0.12 12.0 0.0 5.6 6.5 0.0 3.2 3 0 0 3 3 3 0 Archaeal ATPase SRP54 PF00448.17 CAM68048.2 - 0.14 11.6 2.6 10 5.4 0.0 3.9 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain AAA_24 PF13479.1 CAM68048.2 - 0.19 11.2 4.3 8.7 5.8 0.0 4.3 5 0 0 5 5 4 0 AAA domain AAA_11 PF13086.1 CAM68048.2 - 0.34 10.4 9.1 2.8 7.4 0.0 4.4 5 0 0 5 5 4 0 AAA domain TIP49 PF06068.8 CAM68048.2 - 0.49 9.0 0.4 38 2.8 0.0 3.0 3 0 0 3 3 3 0 TIP49 C-terminus ABC_tran PF00005.22 CAM68048.2 - 0.6 10.4 11.2 1.3 9.2 0.0 4.5 5 0 0 5 5 3 0 ABC transporter AAA_23 PF13476.1 CAM68048.2 - 1.4 9.2 6.1 44 4.3 0.0 4.9 5 0 0 5 5 3 0 AAA domain Rad17 PF03215.10 CAM68048.2 - 1.6 7.2 0.4 14 4.2 0.0 2.6 4 0 0 4 4 4 0 Rad17 cell cycle checkpoint protein DUF4441 PF14536.1 CAM68048.2 - 2.5 8.0 0.1 9.8 6.1 0.1 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4441) Malectin PF11721.3 CAM68048.2 - 2.6 7.7 0.0 6.3 6.5 0.0 1.6 1 0 0 1 1 1 0 Di-glucose binding within endoplasmic reticulum Myosin_tail_1 PF01576.14 CAM68048.2 - 3 5.4 22.2 0.1 10.2 2.9 2.3 2 0 0 2 2 2 0 Myosin tail APG6 PF04111.7 CAM68048.2 - 8.8 5.2 21.1 4 6.3 1.0 3.5 3 0 0 3 3 3 0 Autophagy protein Apg6 Lactamase_B_2 PF12706.2 CAM68049.1 - 6.9e-13 48.5 0.1 1e-12 48.0 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CAM68049.1 - 9.9e-08 31.8 0.1 1.8e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CAM68050.1 - 5.3e-09 35.9 0.0 1.4e-08 34.5 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CAM68050.1 - 2.8e-05 23.8 0.0 6.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Adap_comp_sub PF00928.16 CAM68051.1 - 3.5e-83 278.7 0.4 4e-83 278.5 0.3 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Pkinase PF00069.20 CAM68052.1 - 2.9e-14 52.8 0.0 1.7e-06 27.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAM68052.1 - 0.0014 17.7 0.0 0.1 11.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 CAM68054.1 - 1.9e-26 92.7 0.0 2.5e-21 75.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAM68054.1 - 2.1e-07 30.2 0.0 4.6e-07 29.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM68054.1 - 3.3e-05 23.0 0.0 5.8e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like CTP_transf_1 PF01148.15 CAM68055.1 - 0.91 9.1 9.8 1.3 8.5 6.8 1.3 1 0 0 1 1 1 0 Cytidylyltransferase family ChaC PF04752.7 CAM68056.1 - 5.6e-47 159.9 0.0 6.8e-47 159.7 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein ChaC PF04752.7 CAM68057.1 - 1.2e-44 152.3 0.0 2.3e-43 148.2 0.0 2.0 1 1 0 1 1 1 1 ChaC-like protein WD40 PF00400.27 CAM68058.1 - 7.9e-12 44.5 2.5 1.8e-06 27.6 0.0 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat UMP1 PF05348.6 CAM68058.1 - 0.12 12.3 0.1 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 Proteasome maturation factor UMP1 Peptidase_S21 PF00716.12 CAM68058.1 - 1.1 8.5 14.7 0.02 14.2 1.0 2.9 3 0 0 3 3 3 0 Assemblin (Peptidase family S21) SHS2_Rpb7-N PF03876.12 CAM68060.2 - 0.00019 21.5 0.0 0.013 15.5 0.0 2.6 2 0 0 2 2 2 2 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 GTP_EFTU PF00009.22 CAM68061.1 - 1.7e-36 125.4 2.2 9.1e-36 123.0 1.5 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CAM68061.1 - 2.8e-07 30.5 0.1 5.2e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CAM68061.1 - 1e-05 24.8 0.1 2e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 CAM68061.1 - 6.2e-05 23.4 0.0 0.00016 22.1 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 CAM68061.1 - 0.00014 21.3 0.1 0.0004 19.9 0.1 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 CAM68061.1 - 0.00026 20.2 0.0 0.00053 19.2 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 CAM68061.1 - 0.005 16.6 2.7 0.62 9.8 0.1 2.9 2 1 1 3 3 3 2 Dynamin family IF-2 PF11987.3 CAM68061.1 - 0.0052 16.6 0.0 0.017 14.9 0.0 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 FlxA PF14282.1 CAM68064.1 - 0.02 14.8 3.2 16 5.4 0.0 3.8 4 0 0 4 4 4 0 FlxA-like protein Spc7 PF08317.6 CAM68064.1 - 0.086 11.4 12.7 0.054 12.1 2.6 2.6 2 0 0 2 2 2 0 Spc7 kinetochore protein Streptin-Immun PF11083.3 CAM68064.1 - 0.7 9.9 5.5 3.9 7.5 0.0 3.4 3 0 0 3 3 3 0 Lantibiotic streptin immunity protein Phage_GP20 PF06810.6 CAM68064.1 - 4.5 6.6 7.5 4.4 6.7 0.1 3.6 3 1 1 4 4 4 0 Phage minor structural protein GP20 DUF2203 PF09969.4 CAM68064.1 - 5.6 7.2 9.4 16 5.7 0.0 3.6 4 1 0 4 4 4 0 Uncharacterized conserved protein (DUF2203) IncA PF04156.9 CAM68064.1 - 7.4 6.1 35.5 0.26 10.8 6.8 4.1 4 0 0 4 4 4 0 IncA protein MORN PF02493.15 CAM68065.2 - 6.1e-46 151.4 83.3 7.4e-05 22.2 1.4 12.9 13 0 0 13 13 13 12 MORN repeat EF-hand_1 PF00036.27 CAM68066.1 - 5.3e-25 84.7 9.7 2.6e-08 32.5 0.3 4.4 4 1 1 5 5 5 3 EF hand EF-hand_7 PF13499.1 CAM68066.1 - 7.8e-25 86.8 1.9 9.6e-13 48.0 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CAM68066.1 - 6.5e-21 72.2 5.8 8.1e-08 31.5 0.1 4.4 3 1 1 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 CAM68066.1 - 1.4e-19 69.4 9.1 1.8e-11 43.4 0.3 3.9 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 CAM68066.1 - 1.4e-18 65.2 10.9 6e-06 25.3 0.1 3.9 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.2 CAM68066.1 - 5e-07 29.4 2.8 0.036 13.8 0.5 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 CAM68066.1 - 1e-06 28.5 0.0 9.2e-06 25.4 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.5 CAM68066.1 - 0.022 14.6 0.3 6.6 6.7 0.0 2.7 2 1 0 2 2 2 0 Ca2+ insensitive EF hand FliG_N PF14842.1 CAM68066.1 - 0.049 13.7 0.5 2.7 8.1 0.1 2.3 2 0 0 2 2 2 0 FliG N-terminal domain SPARC_Ca_bdg PF10591.4 CAM68066.1 - 0.082 12.9 0.0 0.21 11.5 0.0 1.7 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Ribosomal_L11 PF00298.14 CAM68066.1 - 0.084 13.0 0.0 12 6.0 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein L11, RNA binding domain DUF3911 PF13050.1 CAM68066.1 - 0.11 12.5 0.0 0.33 11.0 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3911) MIP PF00230.15 CAM68067.1 - 2.7e-24 85.8 14.3 1.3e-23 83.6 9.8 1.8 1 1 0 1 1 1 1 Major intrinsic protein FKBP_C PF00254.23 CAM68068.1 - 4.2e-29 100.4 0.0 4.8e-29 100.2 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase zf-RanBP PF00641.13 CAM68069.1 - 2.9 7.0 7.9 11 5.2 5.5 1.9 1 1 0 1 1 1 0 Zn-finger in Ran binding protein and others Pro_isomerase PF00160.16 CAM68070.1 - 5.6e-37 127.3 0.0 7.2e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD EF-hand_8 PF13833.1 CAM68071.1 - 2.6e-11 42.9 0.1 7.1e-11 41.5 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CAM68071.1 - 0.0064 15.7 0.7 0.028 13.7 0.1 2.3 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 CAM68071.1 - 0.013 15.2 0.1 0.1 12.5 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.1 CAM68071.1 - 0.014 15.4 0.2 0.049 13.7 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain pair DUF4604 PF15377.1 CAM68071.1 - 0.019 15.1 4.2 0.03 14.5 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) DUF3043 PF11241.3 CAM68071.1 - 1.8 8.0 5.2 2.7 7.5 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) TPR_11 PF13414.1 CAM68072.1 - 0.015 14.9 0.0 0.55 9.9 0.0 2.4 2 0 0 2 2 2 0 TPR repeat MAM33 PF02330.11 CAM68073.1 - 1.2e-14 54.5 0.3 2.3e-14 53.6 0.2 1.6 1 1 0 1 1 1 1 Mitochondrial glycoprotein Metallophos PF00149.23 CAM68074.1 - 2.3e-07 30.4 0.0 0.00017 21.0 0.0 2.3 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CAM68074.1 - 0.0095 15.7 0.4 0.5 10.1 0.1 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain DUF4440 PF14534.1 CAM68074.1 - 0.093 12.9 0.0 0.24 11.6 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) HA2 PF04408.18 CAM68075.1 - 1.2e-16 60.5 0.1 2.8e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CAM68075.1 - 2e-12 46.7 0.1 4.7e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAM68075.1 - 7.8e-10 38.5 0.1 2.6e-08 33.5 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CAM68075.1 - 0.0001 22.4 0.0 0.00036 20.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain R3H PF01424.17 CAM68075.1 - 0.00081 19.0 0.0 0.0027 17.3 0.0 2.0 1 0 0 1 1 1 1 R3H domain Miro PF08477.8 CAM68075.1 - 0.061 13.8 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein T2SE PF00437.15 CAM68075.1 - 0.077 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.22 CAM68075.1 - 0.095 12.9 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter UPF0079 PF02367.12 CAM68075.1 - 0.17 11.5 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 CAM68075.1 - 0.17 10.6 0.0 0.3 9.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_23 PF13476.1 CAM68075.1 - 0.3 11.3 0.0 0.6 10.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ribosomal_L14e PF01929.12 CAM68077.1 - 1.9e-23 82.6 3.1 1.9e-23 82.6 2.1 2.1 2 1 0 2 2 2 1 Ribosomal protein L14 KOW PF00467.24 CAM68077.1 - 3.9e-05 23.1 0.6 6.9e-05 22.4 0.4 1.4 1 0 0 1 1 1 1 KOW motif SP2 PF03014.9 CAM68077.1 - 0.0022 15.9 0.1 0.0032 15.4 0.0 1.2 1 0 0 1 1 1 1 Structural protein 2 CoaE PF01121.15 CAM68078.1 - 1.2e-42 145.2 0.0 2.3e-42 144.4 0.0 1.4 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.1 CAM68078.1 - 5.8e-05 23.4 0.5 0.08 13.2 0.0 2.8 2 2 2 4 4 4 2 AAA domain AAA_17 PF13207.1 CAM68078.1 - 0.00032 21.5 0.1 0.00062 20.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 CAM68078.1 - 0.0032 17.3 0.3 0.076 12.9 0.2 2.2 1 1 0 1 1 1 1 Cytidylate kinase-like family PRK PF00485.13 CAM68078.1 - 0.022 14.3 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family A_deaminase_N PF08451.6 CAM68078.1 - 0.034 14.1 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 Adenosine/AMP deaminase N-terminal SKI PF01202.17 CAM68078.1 - 0.091 12.6 0.0 0.49 10.2 0.0 2.0 2 0 0 2 2 2 0 Shikimate kinase tRNA-synt_2c PF01411.14 CAM68079.1 - 4.2e-193 642.6 0.0 5.4e-193 642.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 CAM68079.1 - 3.5e-11 42.8 0.0 8.5e-11 41.5 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 CAM68079.1 - 0.00025 20.6 1.1 0.00087 18.9 0.7 1.9 1 0 0 1 1 1 1 DHHA1 domain SpoA PF01052.15 CAM68080.1 - 0.025 14.1 0.0 0.059 12.9 0.0 1.6 1 0 0 1 1 1 0 Surface presentation of antigens (SPOA) PTEN_C2 PF10409.4 CAM68080.1 - 0.08 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein Ribosomal_L14e PF01929.12 CAM68081.1 - 1.9e-23 82.6 3.1 1.9e-23 82.6 2.1 2.1 2 1 0 2 2 2 1 Ribosomal protein L14 KOW PF00467.24 CAM68081.1 - 3.9e-05 23.1 0.6 6.9e-05 22.4 0.4 1.4 1 0 0 1 1 1 1 KOW motif SP2 PF03014.9 CAM68081.1 - 0.0022 15.9 0.1 0.0032 15.4 0.0 1.2 1 0 0 1 1 1 1 Structural protein 2 PBP_sp32 PF07222.7 CAM68082.1 - 0.028 13.5 3.5 0.026 13.6 0.9 1.8 2 0 0 2 2 2 0 Proacrosin binding protein sp32 RNase_PH PF01138.16 CAM68083.1 - 4.1e-09 36.8 0.0 7.5e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CAM68083.1 - 0.00014 21.6 0.1 0.00029 20.7 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Metallophos PF00149.23 CAM68085.1 - 3.2e-09 36.4 0.5 6.8e-08 32.1 0.0 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CAM68085.1 - 3.8e-07 30.0 0.0 6.8e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF737 PF05300.6 CAM68085.1 - 0.071 13.0 0.0 0.071 13.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF737) Motile_Sperm PF00635.21 CAM68087.1 - 6.2e-08 32.2 0.0 11 5.7 0.0 8.7 11 0 0 11 11 11 1 MSP (Major sperm protein) domain PapD-like PF14874.1 CAM68087.1 - 7.6e-05 22.6 15.1 0.013 15.4 0.0 8.0 7 1 1 8 8 8 2 Flagellar-associated PapD-like Transglut_C PF00927.17 CAM68087.1 - 0.00034 20.6 1.9 9.2 6.3 0.0 6.1 8 0 0 8 8 8 2 Transglutaminase family, C-terminal ig like domain Gryzun-like PF12742.2 CAM68087.1 - 0.27 11.0 0.0 2.6 7.9 0.0 2.4 2 0 0 2 2 2 0 Gryzun, putative Golgi trafficking CAF1 PF04857.15 CAM68088.1 - 7.2e-62 209.0 0.2 1.1e-61 208.5 0.1 1.3 1 0 0 1 1 1 1 CAF1 family ribonuclease cobW PF02492.14 CAM68090.1 - 3.1e-26 91.8 0.1 4.3e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 CAM68090.1 - 0.00062 19.4 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CobW_C PF07683.9 CAM68090.1 - 0.0029 17.2 0.0 0.0065 16.1 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_16 PF13191.1 CAM68090.1 - 0.0034 17.3 0.0 0.0081 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain TrwB_AAD_bind PF10412.4 CAM68090.1 - 0.0058 15.3 0.0 0.009 14.6 0.0 1.2 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_33 PF13671.1 CAM68090.1 - 0.014 15.2 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CAM68090.1 - 0.018 15.1 0.0 0.034 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CAM68090.1 - 0.037 14.3 0.0 0.077 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 CAM68090.1 - 0.039 13.4 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.12 CAM68090.1 - 0.088 12.3 0.0 0.33 10.4 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RINT1_TIP1 PF04437.8 CAM68091.1 - 0.11 11.0 0.0 0.15 10.5 0.0 1.2 1 0 0 1 1 1 0 RINT-1 / TIP-1 family PI-PLC-X PF00388.14 CAM68093.1 - 3.5e-59 198.3 0.0 7.7e-59 197.2 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 CAM68093.1 - 3.1e-34 117.4 0.0 7e-34 116.3 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 CAM68093.1 - 7.2e-11 41.7 0.0 1.4e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.1 CAM68093.1 - 2.8e-05 24.1 0.2 7.6e-05 22.7 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CAM68093.1 - 0.00015 20.8 0.1 0.00057 19.0 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 CAM68093.1 - 0.0027 17.4 0.1 0.1 12.5 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain Toprim_2 PF13155.1 CAM68093.1 - 0.095 13.0 0.1 0.47 10.8 0.0 2.1 2 0 0 2 2 2 0 Toprim-like Lebercilin PF15619.1 CAM68102.1 - 7.3e-18 64.6 267.1 0.08 12.3 0.9 24.7 5 1 25 31 31 31 27 Ciliary protein causing Leber congenital amaurosis disease DUF641 PF04859.7 CAM68102.1 - 4e-12 46.0 189.5 0.12 12.1 4.7 17.3 5 2 20 26 26 26 23 Plant protein of unknown function (DUF641) Myosin_tail_1 PF01576.14 CAM68102.1 - 2.6e-08 32.1 289.6 3.5e-07 28.3 101.1 5.5 3 2 2 5 5 5 2 Myosin tail CALCOCO1 PF07888.6 CAM68102.1 - 0.0011 17.4 6.3 0.0011 17.4 4.3 13.0 4 1 14 18 18 18 14 Calcium binding and coiled-coil domain (CALCOCO1) like Reo_sigmaC PF04582.7 CAM68102.1 - 0.0016 17.6 42.7 1.7 7.7 0.5 8.4 2 1 7 9 9 9 8 Reovirus sigma C capsid protein Fez1 PF06818.10 CAM68102.1 - 0.015 15.3 0.8 0.015 15.3 0.5 14.0 5 2 9 14 14 14 0 Fez1 DUF3573 PF12097.3 CAM68102.1 - 0.73 8.3 0.0 32 2.9 0.0 3.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DNA_Packaging_2 PF11123.3 CAM68103.2 - 0.0021 17.9 0.2 0.0097 15.7 0.1 2.3 2 0 0 2 2 2 1 DNA packaging protein Filament PF00038.16 CAM68103.2 - 0.0061 16.0 10.2 0.0061 16.0 7.1 2.6 2 1 0 2 2 2 1 Intermediate filament protein TMF_DNA_bd PF12329.3 CAM68103.2 - 0.0069 16.1 2.9 0.0069 16.1 2.0 3.4 3 1 0 3 3 3 1 TATA element modulatory factor 1 DNA binding DUF2580 PF10824.3 CAM68103.2 - 0.028 14.7 0.4 0.028 14.7 0.3 3.4 2 1 0 3 3 3 0 Protein of unknown function (DUF2580) Reo_sigmaC PF04582.7 CAM68103.2 - 0.24 10.5 4.8 0.11 11.6 1.1 1.9 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF3508 PF12018.3 CAM68103.2 - 2.6 6.9 6.7 10 5.0 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3508) DUF3138 PF11336.3 CAM68103.2 - 3.6 5.6 5.2 6.9 4.7 3.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Spc7 PF08317.6 CAM68103.2 - 3.7 6.1 13.2 0.3 9.7 3.9 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein LMBR1 PF04791.11 CAM68103.2 - 7.4 5.0 5.2 0.96 7.9 0.7 1.6 2 0 0 2 2 2 0 LMBR1-like membrane protein UTP15_C PF09384.5 CAM68107.1 - 4.9e-37 126.8 1.7 7.7e-37 126.2 1.1 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 CAM68107.1 - 1.1e-19 69.5 0.6 9.1e-05 22.1 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat AhpC-TSA PF00578.16 CAM68108.1 - 1.5e-39 134.4 0.0 2e-39 134.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CAM68108.1 - 1.3e-15 57.2 0.0 1.6e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CAM68108.1 - 8.9e-09 34.8 0.1 1.6e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Pro_isomerase PF00160.16 CAM68109.1 - 5.2e-47 159.9 0.0 7.7e-47 159.3 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Arginase PF00491.16 CAM68111.1 - 6.4e-38 130.6 0.0 7.4e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 Arginase family Tropomyosin_1 PF12718.2 CAM68112.1 - 7.1e-05 22.6 3.4 7.1e-05 22.6 2.4 4.4 1 1 3 4 4 4 2 Tropomyosin like Receptor_IA-2 PF11548.3 CAM68112.1 - 0.035 14.0 0.2 0.13 12.1 0.1 2.0 1 0 0 1 1 1 0 Protein-tyrosine phosphatase receptor IA-2 KaiC PF06745.8 CAM68112.1 - 4.4 6.3 10.7 0.42 9.6 4.0 1.9 2 1 0 2 2 2 0 KaiC DUF1767 PF08585.7 CAM68113.1 - 2.5e-14 53.2 0.0 4.2e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) Methyltransf_16 PF10294.4 CAM68114.1 - 2.4e-17 62.9 0.0 3.2e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 CAM68114.1 - 3.6e-10 39.6 0.0 6.2e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAM68114.1 - 1.2e-08 35.2 0.0 4.1e-08 33.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CAM68114.1 - 1.5e-07 30.9 0.0 2.2e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 CAM68114.1 - 7.6e-06 26.4 0.1 1.4e-05 25.6 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CAM68114.1 - 1.4e-05 25.1 0.1 2.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CAM68114.1 - 0.00011 22.6 0.1 0.00028 21.2 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 CAM68114.1 - 0.00021 20.1 0.0 0.00029 19.6 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_25 PF13649.1 CAM68114.1 - 0.00053 20.2 0.1 0.00096 19.4 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CAM68114.1 - 0.0018 17.4 0.0 0.0024 17.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.6 CAM68114.1 - 0.0028 17.0 0.0 0.0043 16.4 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_23 PF13489.1 CAM68114.1 - 0.0091 15.7 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 CAM68114.1 - 0.01 14.5 0.0 0.016 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MethyltransfD12 PF02086.10 CAM68114.1 - 0.053 12.9 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Cons_hypoth95 PF03602.10 CAM68114.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 RrnaAD PF00398.15 CAM68114.1 - 0.18 10.8 0.0 0.25 10.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NTP_transferase PF00483.18 CAM68115.1 - 3.9e-46 157.3 0.0 5.6e-46 156.8 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 CAM68115.1 - 4.4e-12 46.3 0.0 6.3e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 CAM68115.1 - 5.3e-12 44.6 10.8 2.9e-07 29.7 1.4 3.6 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CAM68115.1 - 0.011 15.3 0.7 0.011 15.3 0.5 3.8 4 0 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.14 CAM68115.1 - 0.017 14.7 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase IspD PF01128.14 CAM68115.1 - 0.17 11.3 0.0 0.4 10.1 0.0 1.6 2 0 0 2 2 2 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Beach PF02138.13 CAM68116.1 - 6.8e-90 301.1 0.0 1.2e-89 300.3 0.0 1.5 1 0 0 1 1 1 1 Beige/BEACH domain Laminin_G_3 PF13385.1 CAM68116.1 - 1.7e-07 31.5 0.0 8.2e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.1 CAM68116.1 - 0.0014 18.4 0.0 0.0037 17.0 0.0 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Pro_isomerase PF00160.16 CAM68117.1 - 1.5e-13 51.2 0.0 1.9e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ATP-synt_C PF00137.16 CAM68118.1 - 4.1e-27 93.8 31.8 3.9e-16 58.6 7.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C GerA PF03323.8 CAM68118.1 - 2.3 6.2 6.8 5.2 5.0 0.3 2.1 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein Abhydrolase_6 PF12697.2 CAM68119.1 - 5.1e-27 95.2 2.4 7.7e-27 94.6 1.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CAM68119.1 - 4.4e-13 49.2 0.2 7.7e-13 48.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAM68119.1 - 4.7e-11 42.6 0.0 1.5e-10 41.0 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 CAM68119.1 - 4.2e-05 23.2 0.0 0.00011 21.8 0.0 1.7 1 0 0 1 1 1 1 Serine hydrolase Hydrolase_4 PF12146.3 CAM68119.1 - 6.7e-05 22.6 0.2 0.00019 21.2 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase DUF2305 PF10230.4 CAM68119.1 - 0.0032 16.9 0.0 0.0047 16.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 CAM68119.1 - 0.025 14.1 0.0 0.061 12.9 0.0 1.5 1 1 0 1 1 1 0 PGAP1-like protein LRR_6 PF13516.1 CAM68120.1 - 2.8e-10 39.1 12.3 0.23 11.6 0.0 9.2 10 1 1 11 11 11 3 Leucine Rich repeat LRR_8 PF13855.1 CAM68120.1 - 4.6e-05 23.0 0.4 0.51 10.1 0.0 5.1 3 2 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 CAM68120.1 - 0.00018 21.0 0.6 3.4 7.3 0.0 5.1 2 2 4 6 6 6 3 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 CAM68120.1 - 0.0016 18.3 4.3 71 4.3 0.0 7.3 7 1 0 7 7 7 0 Leucine rich repeat cNMP_binding PF00027.24 CAM68121.1 - 1.9e-08 33.9 0.4 0.01 15.6 0.0 2.7 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain TMF_DNA_bd PF12329.3 CAM68122.1 - 0.019 14.7 1.1 0.019 14.7 0.7 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF342 PF03961.8 CAM68122.1 - 0.064 11.6 0.4 0.082 11.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 CAM68122.1 - 0.074 12.0 4.3 0.095 11.7 3.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4618 PF15397.1 CAM68122.1 - 0.086 12.1 8.5 0.08 12.2 5.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) HAUS6_N PF14661.1 CAM68122.1 - 0.14 11.4 4.9 0.21 10.9 3.4 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DivIC PF04977.10 CAM68122.1 - 0.29 10.6 6.4 0.055 12.9 1.0 2.1 1 1 0 2 2 2 0 Septum formation initiator End3 PF12761.2 CAM68122.1 - 0.71 9.4 6.6 0.87 9.1 4.2 1.4 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 DUF724 PF05266.9 CAM68122.1 - 5.5 6.5 7.9 8.8 5.9 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) YjgF_endoribonc PF14588.1 CAM68125.1 - 2.3e-32 111.9 0.1 2.6e-32 111.8 0.1 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.16 CAM68125.1 - 4e-19 68.5 0.0 5.6e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP ABC_membrane PF00664.18 CAM68126.1 - 4.4e-51 173.8 28.3 1.1e-25 90.6 5.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CAM68126.1 - 4.6e-51 172.7 0.0 9.3e-27 93.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_25 PF13481.1 CAM68126.1 - 2.6e-09 36.7 0.1 6.7e-06 25.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CAM68126.1 - 2.9e-09 36.3 0.4 0.0015 18.0 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 CAM68126.1 - 6.8e-08 32.0 3.3 0.1 11.8 0.0 4.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CAM68126.1 - 9.9e-08 32.2 0.0 0.2 11.5 0.0 4.2 3 1 1 4 4 4 2 AAA domain FtsK_SpoIIIE PF01580.13 CAM68126.1 - 1e-07 31.6 0.2 0.0023 17.4 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family T2SE PF00437.15 CAM68126.1 - 1.9e-07 30.2 0.0 0.00026 19.9 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.1 CAM68126.1 - 6.4e-06 26.2 0.1 0.0016 18.4 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.1 CAM68126.1 - 1.4e-05 25.5 0.0 0.027 14.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 CAM68126.1 - 2.3e-05 24.0 0.2 0.038 13.4 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain Miro PF08477.8 CAM68126.1 - 3.3e-05 24.3 0.2 0.25 11.8 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein Viral_helicase1 PF01443.13 CAM68126.1 - 4.2e-05 23.1 0.0 0.003 17.1 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 CAM68126.1 - 5.3e-05 23.3 0.1 0.022 14.8 0.0 2.9 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.12 CAM68126.1 - 6.4e-05 22.8 1.8 0.17 11.7 0.3 2.3 2 0 0 2 2 2 2 Domain of unknown function DUF87 DUF258 PF03193.11 CAM68126.1 - 7.8e-05 21.9 0.2 0.012 14.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 CAM68126.1 - 0.00015 21.6 0.2 0.56 10.1 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase NACHT PF05729.7 CAM68126.1 - 0.00022 20.9 0.8 0.078 12.6 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_17 PF13207.1 CAM68126.1 - 0.00056 20.7 0.5 2.4 8.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 CAM68126.1 - 0.00089 19.1 0.0 0.09 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 CAM68126.1 - 0.00091 18.9 1.1 1.2 8.8 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 CAM68126.1 - 0.00097 18.6 1.6 0.29 10.5 0.1 3.0 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain TrwB_AAD_bind PF10412.4 CAM68126.1 - 0.0011 17.6 0.1 0.33 9.5 0.0 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.1 CAM68126.1 - 0.0036 17.5 0.2 2 8.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CAM68126.1 - 0.0071 16.0 0.0 0.43 10.2 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase AAA_33 PF13671.1 CAM68126.1 - 0.0098 15.7 0.2 0.61 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 CAM68126.1 - 0.011 15.3 0.2 3.2 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 CAM68126.1 - 0.011 15.2 0.5 2.7 7.4 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein CAP_GLY PF01302.20 CAM68126.1 - 0.017 14.8 0.0 0.043 13.5 0.0 1.7 1 0 0 1 1 1 0 CAP-Gly domain RNA_helicase PF00910.17 CAM68126.1 - 0.019 15.1 0.0 1.6 8.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Pox_A32 PF04665.7 CAM68126.1 - 0.024 13.9 0.9 4.1 6.6 0.1 2.5 2 0 0 2 2 2 0 Poxvirus A32 protein ArgK PF03308.11 CAM68126.1 - 0.025 13.3 0.2 6.7 5.3 0.0 2.3 2 0 0 2 2 2 0 ArgK protein AAA_28 PF13521.1 CAM68126.1 - 0.031 14.2 0.3 0.25 11.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 CAM68126.1 - 0.061 12.1 0.1 6.5 5.5 0.1 2.2 2 0 0 2 2 2 0 NB-ARC domain Adeno_IVa2 PF02456.10 CAM68126.1 - 0.14 10.8 0.0 0.54 8.8 0.0 1.8 2 0 0 2 2 2 0 Adenovirus IVa2 protein ATP-synt_ab PF00006.20 CAM68126.1 - 0.19 11.2 0.9 1.5 8.2 0.0 2.5 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.18 CAM68126.1 - 0.33 10.7 3.6 2.2 8.0 0.4 2.6 2 0 0 2 2 2 0 Dynamin family Septin PF00735.13 CAM68126.1 - 0.62 9.0 0.5 5.9 5.8 0.0 2.1 2 0 0 2 2 2 0 Septin DAP3 PF10236.4 CAM68126.1 - 0.64 8.9 0.7 13 4.6 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_15 PF13175.1 CAM68126.1 - 1.2 8.0 0.0 16 4.3 0.0 2.2 3 0 0 3 3 2 0 AAA ATPase domain ABC_membrane PF00664.18 CAM68127.1 - 9.3e-56 189.2 29.2 7.4e-31 107.5 7.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CAM68127.1 - 1.2e-50 171.3 0.0 9.3e-27 94.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_25 PF13481.1 CAM68127.1 - 1.8e-09 37.3 0.1 4.9e-06 26.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CAM68127.1 - 2.4e-09 36.5 0.5 0.0015 17.9 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 CAM68127.1 - 4.4e-08 32.6 3.0 0.1 11.8 0.0 4.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CAM68127.1 - 9.9e-08 32.2 0.0 0.21 11.4 0.1 4.2 3 1 0 4 4 4 2 AAA domain FtsK_SpoIIIE PF01580.13 CAM68127.1 - 2.4e-07 30.4 0.1 0.0058 16.1 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family Viral_helicase1 PF01443.13 CAM68127.1 - 1.7e-06 27.7 0.0 0.0014 18.1 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 CAM68127.1 - 3.4e-06 26.1 0.0 0.0052 15.7 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.1 CAM68127.1 - 6.7e-06 26.2 0.1 0.002 18.1 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.1 CAM68127.1 - 1.5e-05 25.4 0.0 0.026 14.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CAM68127.1 - 1.7e-05 24.9 0.3 0.019 15.1 0.0 3.6 4 0 0 4 4 3 1 AAA domain AAA_10 PF12846.2 CAM68127.1 - 2.4e-05 23.9 0.2 0.044 13.2 0.0 2.5 2 0 0 2 2 2 2 AAA-like domain Miro PF08477.8 CAM68127.1 - 3.4e-05 24.3 0.2 0.23 11.9 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein DUF87 PF01935.12 CAM68127.1 - 5.6e-05 23.0 1.8 0.16 11.7 0.3 2.4 2 0 0 2 2 2 2 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 CAM68127.1 - 0.00015 21.6 0.1 0.56 10.1 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 CAM68127.1 - 0.00015 20.9 0.2 0.024 13.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 NACHT PF05729.7 CAM68127.1 - 0.00018 21.2 0.6 0.075 12.6 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_17 PF13207.1 CAM68127.1 - 0.00058 20.6 0.5 2.2 9.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 CAM68127.1 - 0.00073 19.4 0.0 0.07 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.4 CAM68127.1 - 0.0011 17.7 0.2 0.29 9.7 0.0 2.2 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain MobB PF03205.9 CAM68127.1 - 0.0013 18.4 1.3 1.5 8.5 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 CAM68127.1 - 0.0018 17.7 1.5 0.26 10.7 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 CAM68127.1 - 0.0037 17.5 0.1 2 8.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.12 CAM68127.1 - 0.006 16.1 0.3 2.5 7.6 0.0 2.8 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 CAM68127.1 - 0.0083 16.0 0.4 0.66 9.8 0.1 2.8 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CAM68127.1 - 0.0097 15.6 0.0 0.55 9.8 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase RNA_helicase PF00910.17 CAM68127.1 - 0.017 15.2 0.0 1.3 9.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase ArgK PF03308.11 CAM68127.1 - 0.022 13.5 0.2 5.7 5.6 0.0 2.3 2 0 0 2 2 2 0 ArgK protein CAP_GLY PF01302.20 CAM68127.1 - 0.029 14.0 0.0 0.079 12.6 0.0 1.7 1 0 0 1 1 1 0 CAP-Gly domain Pox_A32 PF04665.7 CAM68127.1 - 0.039 13.2 1.2 4.6 6.4 0.2 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein NB-ARC PF00931.17 CAM68127.1 - 0.054 12.3 0.1 6.4 5.5 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.1 CAM68127.1 - 0.055 13.4 0.2 0.48 10.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 CAM68127.1 - 0.21 11.0 0.8 2.1 7.7 0.0 2.6 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.18 CAM68127.1 - 0.24 11.1 2.8 1.8 8.3 0.2 2.4 2 0 0 2 2 2 0 Dynamin family Septin PF00735.13 CAM68127.1 - 0.55 9.1 0.5 5.3 5.9 0.0 2.1 2 0 0 2 2 2 0 Septin AAA_15 PF13175.1 CAM68127.1 - 1.1 8.2 0.0 14 4.5 0.0 2.2 3 0 0 3 3 2 0 AAA ATPase domain DUF3311 PF11755.3 CAM68130.1 - 0.062 12.8 0.3 0.12 11.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3311) Yip1 PF04893.12 CAM68131.1 - 2.2e-16 59.8 18.1 2.9e-16 59.4 12.5 1.3 1 1 0 1 1 1 1 Yip1 domain DUF2964 PF11177.3 CAM68131.1 - 0.1 12.5 2.4 0.24 11.3 1.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2964) DUF1282 PF06930.7 CAM68131.1 - 0.92 9.1 11.4 1.5 8.4 7.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) ABC_membrane PF00664.18 CAM68132.1 - 3e-69 233.4 25.6 1e-38 133.3 2.1 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CAM68132.1 - 1.2e-50 171.3 0.0 9.3e-27 93.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.1 CAM68132.1 - 1.9e-08 33.6 0.3 0.0076 15.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain CAP_GLY PF01302.20 CAM68132.1 - 5.4e-08 32.4 0.0 1.4e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 CAP-Gly domain SMC_N PF02463.14 CAM68132.1 - 9.9e-08 31.4 4.3 0.11 11.7 0.0 4.2 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CAM68132.1 - 7.8e-07 29.3 0.0 2.4 8.0 0.2 4.1 3 1 1 4 4 4 2 AAA domain FtsK_SpoIIIE PF01580.13 CAM68132.1 - 2.7e-06 26.9 0.1 0.089 12.2 0.0 2.7 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_25 PF13481.1 CAM68132.1 - 2.9e-06 26.8 0.0 0.008 15.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 CAM68132.1 - 2.7e-05 24.6 0.2 0.15 12.5 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein T2SE PF00437.15 CAM68132.1 - 3.4e-05 22.8 0.2 0.054 12.3 0.0 2.6 3 0 0 3 3 2 2 Type II/IV secretion system protein AAA_17 PF13207.1 CAM68132.1 - 3.8e-05 24.5 0.5 0.21 12.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 CAM68132.1 - 4.2e-05 22.8 0.1 0.0062 15.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 CAM68132.1 - 8.2e-05 22.1 0.3 0.13 11.6 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain AAA_16 PF13191.1 CAM68132.1 - 0.00021 21.3 0.3 0.77 9.7 0.0 3.6 3 0 0 3 3 3 1 AAA ATPase domain MMR_HSR1 PF01926.18 CAM68132.1 - 0.00021 21.1 0.2 0.56 10.1 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.1 CAM68132.1 - 0.00023 21.5 0.3 0.38 11.0 0.1 2.2 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 CAM68132.1 - 0.0015 18.4 3.6 0.54 10.0 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_22 PF13401.1 CAM68132.1 - 0.0018 18.4 0.1 0.98 9.5 0.0 3.2 3 0 0 3 3 2 1 AAA domain MobB PF03205.9 CAM68132.1 - 0.0024 17.6 2.5 1.5 8.5 0.1 2.8 3 0 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B TrwB_AAD_bind PF10412.4 CAM68132.1 - 0.0029 16.2 0.3 0.7 8.4 0.0 2.2 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_14 PF13173.1 CAM68132.1 - 0.0042 16.9 0.1 0.38 10.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 CAM68132.1 - 0.0056 16.3 1.8 1.2 8.8 0.1 2.5 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.1 CAM68132.1 - 0.0057 16.9 0.1 3.2 8.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CAM68132.1 - 0.0072 16.2 0.3 0.71 9.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain Dynamin_N PF00350.18 CAM68132.1 - 0.0086 15.9 0.1 0.39 10.5 0.0 2.5 2 0 0 2 2 2 1 Dynamin family cobW PF02492.14 CAM68132.1 - 0.014 14.8 0.2 4.3 6.7 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.13 CAM68132.1 - 0.022 14.2 0.1 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 CAM68132.1 - 0.025 14.7 0.0 2.5 8.3 0.0 2.9 2 0 0 2 2 2 0 RNA helicase Pox_A32 PF04665.7 CAM68132.1 - 0.033 13.4 0.4 5.7 6.1 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein ATP_bind_1 PF03029.12 CAM68132.1 - 0.047 13.2 1.8 5.1 6.5 0.2 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.13 CAM68132.1 - 0.095 11.6 0.4 1 8.3 0.0 2.1 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.4 CAM68132.1 - 0.15 11.5 2.4 5.6 6.4 0.0 3.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.17 CAM68132.1 - 0.29 9.9 0.6 6.5 5.5 0.1 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_15 PF13175.1 CAM68132.1 - 2 7.4 0.0 27 3.6 0.0 2.2 3 0 0 3 3 2 0 AAA ATPase domain Arginosuc_synth PF00764.14 CAM68133.1 - 8.2e-148 492.5 0.0 9.6e-148 492.3 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 CAM68133.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC adh_short_C2 PF13561.1 CAM68134.1 - 3e-18 66.4 0.1 1e-13 51.6 0.1 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CAM68134.1 - 1.9e-10 40.9 5.0 1.3e-06 28.4 3.5 3.2 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 CAM68134.1 - 0.047 13.1 0.1 0.8 9.0 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family zf-C3HC4 PF00097.20 CAM68135.1 - 1.9e-06 27.4 7.4 3.6e-06 26.5 5.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAM68135.1 - 0.0027 17.4 7.4 0.0057 16.3 5.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CAM68135.1 - 0.0054 16.5 8.9 0.013 15.3 6.2 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CAM68135.1 - 0.016 14.9 2.6 0.042 13.5 1.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 CAM68135.1 - 0.022 14.7 11.0 0.05 13.6 7.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TF_Zn_Ribbon PF08271.7 CAM68135.1 - 0.076 12.3 5.4 0.18 11.1 3.7 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding zf-RING_6 PF14835.1 CAM68135.1 - 0.21 11.3 5.0 1.4 8.7 3.5 2.2 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_2 PF13639.1 CAM68135.1 - 2.1 8.2 10.1 4.8 7.0 7.0 1.6 1 0 0 1 1 1 0 Ring finger domain Hus1 PF04005.7 CAM68136.1 - 2.3e-85 286.1 0.0 2.5e-85 285.9 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein tRNA-synt_1b PF00579.20 CAM68137.1 - 1.2e-16 60.7 0.0 2.8e-16 59.4 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) AAA_16 PF13191.1 CAM68138.1 - 0.00011 22.2 0.2 0.00037 20.5 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 CAM68138.1 - 0.0041 17.4 0.0 0.0092 16.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_5 PF07728.9 CAM68138.1 - 0.0043 16.7 0.0 0.018 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CAM68138.1 - 0.0044 16.8 0.0 0.014 15.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CAM68138.1 - 0.0074 15.3 0.0 0.019 13.9 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus tRNA_lig_kinase PF08303.6 CAM68138.1 - 0.014 15.2 0.0 0.2 11.5 0.0 2.2 1 1 0 1 1 1 0 tRNA ligase kinase domain AAA PF00004.24 CAM68138.1 - 0.025 14.7 0.0 0.058 13.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CAM68138.1 - 0.029 14.5 0.0 0.5 10.5 0.0 3.0 3 1 0 3 3 3 0 AAA domain AAA_18 PF13238.1 CAM68138.1 - 0.031 14.5 0.0 0.11 12.8 0.0 1.9 3 0 0 3 3 1 0 AAA domain MobB PF03205.9 CAM68138.1 - 0.045 13.4 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Mg_chelatase PF01078.16 CAM68138.1 - 0.047 12.8 0.0 0.18 10.9 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 CAM68138.1 - 0.059 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.1 CAM68138.1 - 0.14 13.0 0.0 0.33 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CAM68138.1 - 0.29 11.0 0.0 0.64 9.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Proteasom_PSMB PF10508.4 CAM68138.1 - 0.34 9.1 0.0 0.52 8.5 0.0 1.1 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit AAA_21 PF13304.1 CAM68138.1 - 0.92 9.4 0.0 1.3 8.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain Pex14_N PF04695.8 CAM68138.1 - 7 6.7 8.1 0.95 9.5 1.7 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region V-ATPase_G PF03179.10 CAM68141.1 - 2.9e-22 78.9 13.7 3.2e-22 78.8 9.5 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Sigma70_r3 PF04539.11 CAM68141.1 - 0.13 12.1 0.6 0.13 12.1 0.4 1.8 2 0 0 2 2 2 0 Sigma-70 region 3 NolV PF06635.7 CAM68141.1 - 0.33 10.0 3.2 0.46 9.6 2.2 1.3 1 0 0 1 1 1 0 Nodulation protein NolV YlqD PF11068.3 CAM68141.1 - 0.51 10.3 8.1 0.6 10.1 5.6 1.2 1 0 0 1 1 1 0 YlqD protein AIF-MLS PF14962.1 CAM68141.1 - 0.87 9.2 5.1 1.1 8.9 3.5 1.1 1 0 0 1 1 1 0 Mitochondria Localisation Sequence PKK PF12474.3 CAM68141.1 - 0.96 9.1 11.4 3.9 7.1 7.9 1.9 1 1 0 1 1 1 0 Polo kinase kinase DUF3154 PF11351.3 CAM68141.1 - 1.3 8.7 8.2 0.28 10.9 1.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3154) Frankia_peptide PF14407.1 CAM68141.1 - 2 8.2 9.2 0.79 9.5 1.0 2.7 1 1 1 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. FUSC PF04632.7 CAM68141.1 - 3.5 5.9 5.1 3.4 5.9 3.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4407 PF14362.1 CAM68141.1 - 4.9 6.0 12.2 6 5.7 8.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ADH_N PF08240.7 CAM68143.1 - 1.5e-28 98.7 5.5 1.5e-28 98.7 3.8 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CAM68143.1 - 1.3e-23 82.9 0.0 2.6e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CAM68143.1 - 4.4e-06 25.9 0.2 7.7e-06 25.1 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 CAM68143.1 - 4.9e-05 23.2 0.8 9.2e-05 22.3 0.6 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.16 CAM68143.1 - 7.8e-05 22.2 0.4 0.00014 21.4 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 CAM68143.1 - 8.7e-05 22.6 0.1 0.00021 21.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 CAM68143.1 - 0.0021 18.0 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 CAM68143.1 - 0.0033 17.0 0.4 0.0055 16.3 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 CAM68143.1 - 0.014 15.0 0.1 0.022 14.3 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase XdhC_C PF13478.1 CAM68143.1 - 0.016 15.5 0.0 0.026 14.8 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain ApbA PF02558.11 CAM68143.1 - 0.022 14.2 0.2 0.048 13.1 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 CAM68143.1 - 0.028 14.4 0.1 0.05 13.6 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain DUF364 PF04016.7 CAM68143.1 - 0.067 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF364) UDPG_MGDP_dh_N PF03721.9 CAM68143.1 - 0.096 12.0 0.3 0.16 11.2 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.16 CAM68143.1 - 1.9 8.3 5.4 4.5 7.0 2.2 2.5 2 1 1 3 3 3 0 ThiF family ABC_tran PF00005.22 CAM68145.1 - 1.4e-29 103.1 0.0 2.8e-29 102.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 CAM68145.1 - 2.6e-25 88.8 18.5 2.6e-25 88.8 12.8 3.5 4 0 0 4 4 4 1 ABC-2 type transporter AAA_21 PF13304.1 CAM68145.1 - 4.5e-06 26.8 0.0 9.5e-05 22.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CAM68145.1 - 0.00015 21.7 0.2 0.00034 20.6 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain ABC2_membrane_3 PF12698.2 CAM68145.1 - 0.00017 20.7 17.0 0.00017 20.7 11.8 2.5 3 0 0 3 3 3 1 ABC-2 family transporter protein AAA_29 PF13555.1 CAM68145.1 - 0.0011 18.4 0.1 0.0026 17.2 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 CAM68145.1 - 0.0014 17.8 0.0 0.0029 16.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 CAM68145.1 - 0.0095 16.7 0.1 0.022 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CAM68145.1 - 0.016 15.3 0.0 0.076 13.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 CAM68145.1 - 0.019 15.3 0.0 0.037 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CAM68145.1 - 0.046 13.1 1.3 0.092 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 CAM68145.1 - 0.057 13.7 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 CAM68145.1 - 0.092 11.5 0.3 0.17 10.6 0.2 1.3 1 0 0 1 1 1 0 ArgK protein AAA_28 PF13521.1 CAM68145.1 - 0.12 12.2 0.5 0.23 11.4 0.3 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 CAM68145.1 - 0.14 11.6 0.1 0.25 10.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 CAM68145.1 - 0.15 12.0 0.3 0.8 9.6 0.0 2.5 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.10 CAM68145.1 - 0.25 9.9 0.0 0.38 9.3 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Aldose_epim PF01263.15 CAM68149.1 - 7.6e-56 189.4 0.0 1.4e-54 185.2 0.0 2.0 1 1 0 1 1 1 1 Aldose 1-epimerase FtsX PF02687.16 CAM68151.1 - 3.6e-26 91.2 32.2 8.2e-15 54.6 6.5 5.4 6 0 0 6 6 6 3 FtsX-like permease family CHAP PF05257.11 CAM68152.1 - 1.4e-07 31.1 1.5 0.00037 20.1 0.0 2.4 2 0 0 2 2 2 2 CHAP domain Med3 PF11593.3 CAM68153.1 - 2.5 7.2 8.5 0.21 10.7 1.3 2.0 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal DUF1664 PF07889.7 CAM68154.1 - 0.0091 15.7 3.1 0.0091 15.7 2.1 11.0 8 3 6 14 14 14 3 Protein of unknown function (DUF1664) FlaC_arch PF05377.6 CAM68154.1 - 0.4 10.5 9.4 9.4 6.2 0.1 6.0 6 0 0 6 6 6 0 Flagella accessory protein C (FlaC) AMPKBI PF04739.10 CAM68155.1 - 1.4e-17 63.4 0.1 2.2e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interation domain SET PF00856.23 CAM68158.1 - 5.7e-14 52.7 0.0 3.1e-13 50.3 0.0 1.9 1 1 0 1 1 1 1 SET domain FtsJ PF01728.14 CAM68159.1 - 7.2e-48 162.9 0.0 8.5e-48 162.7 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 CAM68159.1 - 0.0071 16.0 0.0 0.0089 15.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain META PF03724.11 CAM68159.1 - 0.11 12.3 0.0 0.27 11.0 0.0 1.7 1 1 0 1 1 1 0 META domain AMP-binding PF00501.23 CAM68160.1 - 3.8e-88 295.6 0.2 4.5e-88 295.4 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CAM68160.1 - 5.2e-15 56.1 0.4 1.3e-14 54.8 0.3 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain EF-hand_6 PF13405.1 CAM68161.1 - 8e-08 31.5 0.2 0.013 15.3 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 CAM68161.1 - 3.3e-05 23.9 0.0 0.00049 20.1 0.0 2.6 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CAM68161.1 - 4.4e-05 22.4 0.0 0.0049 16.0 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 CAM68161.1 - 0.0067 15.7 0.0 0.57 9.6 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 CAM68161.1 - 0.0072 15.9 0.7 0.11 12.1 0.2 2.8 2 1 1 3 3 3 1 EF-hand domain pair DUF904 PF06005.7 CAM68163.1 - 0.76 10.1 2.7 6 7.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Prefoldin PF02996.12 CAM68163.1 - 0.92 9.1 4.4 2.1 8.0 0.2 2.6 3 0 0 3 3 3 0 Prefoldin subunit Mnd1 PF03962.10 CAM68163.1 - 2.2 7.9 5.2 20 4.8 0.1 2.4 2 0 0 2 2 2 0 Mnd1 family GFO_IDH_MocA PF01408.17 CAM68164.1 - 6.8e-14 52.4 2.3 6.3e-13 49.3 0.2 2.8 2 1 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 CAM68164.1 - 0.015 15.5 0.3 0.99 9.7 0.0 3.2 2 2 1 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 CAM68164.1 - 0.022 15.1 0.1 0.11 12.9 0.0 2.3 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.4 CAM68164.1 - 0.023 14.4 0.7 0.08 12.6 0.0 2.3 2 0 0 2 2 2 0 Rossmann-like domain CAF1 PF04857.15 CAM68168.1 - 7.5e-42 143.4 0.0 1.1e-41 142.8 0.0 1.3 1 1 0 1 1 1 1 CAF1 family ribonuclease Kelch_3 PF13415.1 CAM68169.1 - 3.3e-14 52.5 14.2 2.6e-07 30.6 0.1 6.9 4 2 0 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.1 CAM68169.1 - 1.4e-11 44.0 9.3 0.0024 17.7 0.4 5.0 5 1 0 5 5 5 3 Kelch motif Kelch_4 PF13418.1 CAM68169.1 - 1.6e-11 43.8 13.1 0.0017 18.0 0.0 6.8 5 2 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.1 CAM68169.1 - 1.5e-08 34.4 5.7 0.4 10.9 0.1 5.8 3 1 1 4 4 4 3 Kelch motif Kelch_1 PF01344.20 CAM68169.1 - 2.1e-07 30.3 0.0 0.031 13.8 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 CAM68169.1 - 1e-06 28.2 0.2 1.1 9.0 0.0 5.2 4 0 0 4 4 4 2 Kelch motif tRNA_bind PF01588.15 CAM68170.1 - 6.2e-13 48.3 0.6 8.6e-13 47.9 0.4 1.2 1 0 0 1 1 1 1 Putative tRNA binding domain zf-RanBP PF00641.13 CAM68170.1 - 0.00083 18.4 1.3 0.0017 17.4 0.9 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DZR PF12773.2 CAM68170.1 - 0.026 14.3 2.6 0.059 13.1 1.8 1.6 1 0 0 1 1 1 0 Double zinc ribbon Cache_1 PF02743.13 CAM68170.1 - 0.14 11.7 0.2 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 Cache domain zinc_ribbon_2 PF13240.1 CAM68170.1 - 0.36 10.3 4.1 0.85 9.1 2.8 1.7 1 0 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 CAM68170.1 - 0.5 9.6 6.9 0.3 10.3 3.3 1.8 1 1 0 1 1 1 0 zinc-ribbon domain GCC2_GCC3 PF07699.8 CAM68170.1 - 0.81 9.3 4.6 1.9 8.1 3.2 1.5 1 0 0 1 1 1 0 GCC2 and GCC3 Lactamase_B PF00753.22 CAM68171.1 - 1.1e-10 41.5 3.2 4.1e-08 33.0 0.3 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily PAP2 PF01569.16 CAM68172.1 - 9.7e-12 44.6 2.0 9.7e-12 44.6 1.4 1.7 2 0 0 2 2 2 1 PAP2 superfamily ThiF PF00899.16 CAM68173.1 - 3.9e-46 156.2 4.2 1.4e-33 115.6 0.0 3.0 3 0 0 3 3 3 2 ThiF family UBACT PF02134.16 CAM68173.1 - 6.2e-29 99.3 0.3 5.9e-21 73.8 0.0 3.0 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 CAM68173.1 - 2.7e-28 98.6 0.0 4.8e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 CAM68173.1 - 1.1e-21 75.8 0.2 6.7e-21 73.3 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 CAM68173.1 - 0.002 18.2 0.8 0.62 10.1 0.0 2.6 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase TPR_19 PF14559.1 CAM68173.1 - 0.03 14.6 0.1 0.077 13.3 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Kinesin PF00225.18 CAM68174.1 - 4.3e-87 291.9 0.1 1.1e-86 290.6 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain MitMem_reg PF13012.1 CAM68174.1 - 0.74 9.9 12.1 10 6.2 0.5 3.7 2 1 1 3 3 3 0 Maintenance of mitochondrial structure and function MYCBPAP PF14646.1 CAM68175.1 - 4.2e-08 32.3 6.7 4.3e-06 25.6 0.1 3.2 2 1 0 2 2 2 2 MYCBP-associated protein family HemY_N PF07219.8 CAM68179.1 - 0.063 12.8 0.4 0.063 12.8 0.3 2.6 3 0 0 3 3 3 0 HemY protein N-terminus FliX PF10768.4 CAM68179.1 - 0.54 10.4 4.6 4.6 7.4 0.3 2.5 2 0 0 2 2 2 0 Class II flagellar assembly regulator BING4CT PF08149.6 CAM68181.1 - 4e-32 109.5 0.1 3e-31 106.7 0.0 2.4 2 0 0 2 2 2 1 BING4CT (NUC141) domain WD40 PF00400.27 CAM68181.1 - 5.4e-09 35.5 2.6 5.4e-07 29.2 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat Sec10 PF07393.6 CAM68182.1 - 7.5e-31 107.0 0.5 7.2e-26 90.6 0.0 3.1 2 1 0 3 3 3 3 Exocyst complex component Sec10 Rhomboid_SP PF12595.3 CAM68182.1 - 4.6e-30 104.7 17.6 4.6e-30 104.7 12.2 2.7 2 0 0 2 2 2 1 Rhomboid serine protease DUF3068 PF11271.3 CAM68183.1 - 0.0034 16.4 4.1 0.0061 15.6 2.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3068) DUF3357 PF11837.3 CAM68183.1 - 0.032 14.0 1.1 0.032 14.0 0.8 2.6 2 2 0 2 2 2 0 Domain of unknown function (DUF3357) Staph_haemo PF05480.6 CAM68183.1 - 0.14 11.8 2.1 0.36 10.5 1.5 1.6 1 0 0 1 1 1 0 Staphylococcus haemolytic protein Caldesmon PF02029.10 CAM68183.1 - 0.18 10.2 53.4 0.24 9.7 37.0 1.1 1 0 0 1 1 1 0 Caldesmon DIM1 PF02966.11 CAM68184.1 - 1.5e-31 108.7 0.1 1.4e-27 95.8 0.0 2.1 2 0 0 2 2 2 2 Mitosis protein DIM1 Vezatin PF12632.2 CAM68184.1 - 0.045 12.8 0.1 0.058 12.4 0.1 1.1 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes CPSase_L_chain PF00289.17 CAM68185.1 - 0.076 13.1 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Fibrillarin PF01269.12 CAM68185.1 - 0.3 9.9 0.0 0.49 9.2 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin GFO_IDH_MocA PF01408.17 CAM68186.1 - 1.4e-13 51.4 0.0 2.4e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 CAM68186.1 - 0.025 14.3 0.1 0.073 12.8 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase family, C-terminal alpha/beta domain PriCT_2 PF08707.6 CAM68187.1 - 2.2e-17 62.6 2.1 2.2e-17 62.6 1.5 2.1 2 0 0 2 2 2 1 Primase C terminal 2 (PriCT-2) TFIIA PF03153.8 CAM68187.1 - 1.4 8.7 16.8 2.4 7.9 11.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Zip PF02535.17 CAM68187.1 - 4.5 6.1 10.3 6.7 5.6 7.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Otopetrin PF03189.8 CAM68187.1 - 6 5.7 5.3 9 5.1 3.7 1.1 1 0 0 1 1 1 0 Otopetrin Thiolase_C PF02803.13 CAM68188.1 - 1.4e-12 47.0 0.2 5.7e-11 41.9 0.1 2.5 1 1 1 2 2 2 1 Thiolase, C-terminal domain Thiolase_N PF00108.18 CAM68188.1 - 9.2e-09 34.6 2.4 2.1e-07 30.2 0.4 2.6 2 1 0 2 2 2 2 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 CAM68188.1 - 1.6e-07 31.0 1.0 3.2e-07 30.1 0.3 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 CAM68188.1 - 0.013 15.1 1.3 0.69 9.6 0.8 2.7 2 1 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III COX17 PF05051.8 CAM68189.1 - 1.4e-05 25.0 0.4 2.2e-05 24.3 0.2 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) AMP-binding PF00501.23 CAM68190.1 - 3.5e-87 292.4 0.2 4.3e-87 292.1 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CAM68190.1 - 7.2e-16 58.8 0.3 1.8e-15 57.6 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RRM_1 PF00076.17 CAM68191.1 - 4e-12 45.5 0.0 6.6e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM68191.1 - 5.7e-09 35.8 0.0 1.1e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM68191.1 - 3.8e-07 29.8 0.0 7.2e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAM68192.1 - 1.9e-13 49.8 0.0 3.4e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM68192.1 - 1.2e-06 28.4 0.0 2.4e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM68192.1 - 0.0011 18.7 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MMR_HSR1 PF01926.18 CAM68193.1 - 2.1e-09 37.3 0.0 4.5e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CAM68193.1 - 1.9e-05 24.5 0.1 0.00014 21.7 0.1 2.2 1 1 1 2 2 2 1 Dynamin family DUF258 PF03193.11 CAM68193.1 - 0.0011 18.1 0.0 0.0023 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 CAM68193.1 - 0.0027 17.1 0.0 0.0059 16.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 CAM68193.1 - 0.0055 16.1 0.0 2.1 7.7 0.0 3.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CAM68193.1 - 0.086 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.22 CAM68193.1 - 0.088 13.1 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter DUF1738 PF08401.6 CAM68194.1 - 0.0058 16.3 0.0 0.024 14.3 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1738) DUF1738 PF08401.6 CAM68195.1 - 0.00018 21.1 1.4 0.094 12.4 0.2 3.2 2 1 1 3 3 3 2 Domain of unknown function (DUF1738) DUF676 PF05057.9 CAM68197.1 - 7.9e-13 48.2 0.0 1.9e-10 40.4 0.0 2.6 2 1 0 2 2 2 2 Putative serine esterase (DUF676) DUF1638 PF07796.6 CAM68197.1 - 0.086 12.4 0.1 0.25 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1638) SET PF00856.23 CAM68198.1 - 2.9e-13 50.4 1.4 1.2e-09 38.6 0.3 3.2 2 1 0 2 2 2 2 SET domain zf-MYND PF01753.13 CAM68198.1 - 0.011 15.6 2.4 0.011 15.6 1.7 3.2 5 0 0 5 5 5 0 MYND finger zf-Mss51 PF13824.1 CAM68198.1 - 0.019 14.8 1.0 0.058 13.2 0.7 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Adeno_terminal PF02459.10 CAM68198.1 - 0.077 11.1 0.7 0.11 10.5 0.5 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein FAD-oxidase_C PF02913.14 CAM68200.1 - 1.1e-45 155.9 0.0 2e-45 155.0 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CAM68200.1 - 1.2e-30 105.7 1.9 2.1e-30 104.9 0.4 2.0 2 1 0 2 2 2 1 FAD binding domain SET PF00856.23 CAM68201.1 - 1.5e-10 41.6 0.1 5.3e-10 39.8 0.0 1.9 2 0 0 2 2 2 1 SET domain zf-MYND PF01753.13 CAM68201.1 - 0.89 9.4 15.6 0.06 13.2 6.3 2.5 2 0 0 2 2 2 0 MYND finger Na_H_Exchanger PF00999.16 CAM68202.1 - 5.5e-46 156.8 44.1 7.4e-46 156.3 30.6 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3481 PF11980.3 CAM68203.1 - 0.032 14.0 0.2 0.097 12.5 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) Mucin PF01456.12 CAM68203.1 - 3.9 7.2 12.2 0.21 11.3 3.1 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein Uroplakin_II PF07353.7 CAM68204.1 - 0.0038 16.6 0.4 0.017 14.4 0.1 2.0 2 0 0 2 2 2 1 Uroplakin II Prominin PF05478.6 CAM68204.1 - 0.1 10.1 1.0 0.15 9.5 0.7 1.1 1 0 0 1 1 1 0 Prominin LAT PF15234.1 CAM68204.1 - 0.74 9.2 4.0 0.69 9.3 0.3 2.2 2 0 0 2 2 2 0 Linker for activation of T-cells DUF3481 PF11980.3 CAM68204.1 - 1.5 8.6 4.9 0.46 10.3 0.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3481) TPR_17 PF13431.1 CAM68206.1 - 0.0082 16.2 0.1 0.25 11.6 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 CAM68206.1 - 0.0099 16.2 5.7 3.4 8.0 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat Cornifin PF02389.10 CAM68206.1 - 0.13 11.9 9.8 0.024 14.4 3.6 1.9 2 0 0 2 2 2 0 Cornifin (SPRR) family TPR_12 PF13424.1 CAM68206.1 - 0.7 9.8 8.9 3.1 7.7 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 CAM68206.1 - 1.6 9.5 8.8 1.5 9.6 0.1 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat ADH_zinc_N_2 PF13602.1 CAM68207.2 - 2.2e-11 44.7 0.0 8.1e-11 42.9 0.0 2.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 CAM68207.2 - 1.8e-10 40.4 0.0 4.8e-09 35.8 0.0 2.9 3 1 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CAM68207.2 - 8.9e-10 38.3 0.4 3.6e-09 36.3 0.1 2.1 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ABC1 PF03109.11 CAM68207.2 - 0.16 11.9 0.3 0.37 10.7 0.2 1.5 1 0 0 1 1 1 0 ABC1 family Glyco_hydro_32N PF00251.15 CAM68208.1 - 5.7e-84 282.0 0.6 9e-84 281.4 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 CAM68208.1 - 3.9e-08 33.5 0.0 7.7e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_43 PF04616.9 CAM68208.1 - 4.1e-07 29.3 0.5 6.5e-07 28.7 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 CAM68209.1 - 7.6e-91 304.6 3.2 9.5e-91 304.3 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 CAM68209.1 - 3.1e-08 33.8 0.0 6.8e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR_2 PF13088.1 CAM68209.1 - 0.01 15.1 0.8 0.021 14.1 0.6 1.5 1 0 0 1 1 1 0 BNR repeat-like domain Methyltransf_28 PF02636.12 CAM68210.1 - 5.1e-59 199.7 0.0 6.7e-59 199.3 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase NIF PF03031.13 CAM68211.2 - 0.0097 15.5 0.1 0.039 13.6 0.0 1.9 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Peptidase_M17 PF00883.16 CAM68214.1 - 1.3e-99 333.0 0.0 1.7e-99 332.6 0.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 CAM68214.1 - 1.4e-05 24.7 0.3 0.00016 21.4 0.0 2.7 3 0 0 3 3 3 1 Cytosol aminopeptidase family, N-terminal domain CHB_HEX_C_1 PF13290.1 CAM68215.1 - 1.9e-07 30.7 0.1 5.5e-05 22.8 0.0 2.9 2 0 0 2 2 2 2 Chitobiase/beta-hexosaminidase C-terminal domain CHB_HEX_C PF03174.8 CAM68215.1 - 2.4e-06 27.2 0.2 0.00031 20.5 0.2 3.0 3 0 0 3 3 3 1 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.1 CAM68215.1 - 9.6e-05 22.3 0.1 0.034 14.2 0.0 3.1 3 0 0 3 3 3 2 Fn3 associated ICEA PF05315.6 CAM68217.1 - 0.0075 15.5 0.8 0.033 13.5 0.0 2.1 2 0 0 2 2 2 1 ICEA Protein DUF3576 PF12100.3 CAM68219.1 - 0.0088 16.0 0.0 0.44 10.6 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3576) Cut12 PF11500.3 CAM68219.1 - 0.015 15.0 2.5 0.015 15.0 1.8 2.0 2 1 0 2 2 2 0 Spindle pole body formation-associated protein DUF948 PF06103.6 CAM68219.1 - 0.065 13.0 0.7 0.19 11.6 0.1 2.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) LMBR1 PF04791.11 CAM68219.1 - 0.071 11.6 0.6 0.091 11.3 0.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Lipoprotein_2 PF00921.12 CAM68219.1 - 0.47 10.4 4.1 0.31 11.0 0.4 2.0 2 0 0 2 2 2 0 Borrelia lipoprotein BLOC1_2 PF10046.4 CAM68219.1 - 0.49 10.5 5.2 1.2 9.3 2.2 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IncA PF04156.9 CAM68219.1 - 5.6 6.5 8.2 7.6 6.0 4.2 2.1 1 1 0 2 2 2 0 IncA protein DUF2580 PF10824.3 CAM68222.1 - 0.077 13.3 0.1 0.094 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2580) KIAA1430 PF13879.1 CAM68227.1 - 0.021 15.2 5.2 0.052 13.9 3.1 2.0 1 1 1 2 2 2 0 KIAA1430 homologue 5-FTHF_cyc-lig PF01812.15 CAM68229.1 - 3.7e-13 49.6 1.8 3.8e-09 36.5 0.1 3.8 3 1 0 3 3 3 3 5-formyltetrahydrofolate cyclo-ligase family HIT PF01230.18 CAM68230.1 - 8.9e-12 45.4 0.0 2.3e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 CAM68230.1 - 1.7e-06 28.2 0.2 1.7e-05 25.0 0.2 2.3 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF2410 PF10307.4 CAM68231.1 - 4e-06 26.3 0.0 0.00014 21.2 0.0 2.1 2 0 0 2 2 2 2 Hypothetical protein (DUF2410) XET_C PF06955.7 CAM68231.1 - 0.023 14.3 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 Xyloglucan endo-transglycosylase (XET) C-terminus LRR_4 PF12799.2 CAM68233.1 - 1e-22 79.2 10.5 7.1e-05 22.3 0.0 7.7 6 1 1 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM68233.1 - 4.4e-09 35.9 20.3 0.29 10.9 0.1 7.1 3 2 4 7 7 7 5 Leucine rich repeat LRR_1 PF00560.28 CAM68233.1 - 9.1e-05 21.9 13.4 23 5.5 0.0 8.6 7 4 0 7 7 7 0 Leucine Rich Repeat LRR_5 PF13306.1 CAM68233.1 - 0.0029 17.2 3.2 0.38 10.4 0.0 3.4 2 1 1 3 3 3 1 Leucine rich repeats (6 copies) LRR_6 PF13516.1 CAM68233.1 - 0.013 15.4 19.3 64 4.0 0.0 9.6 11 1 0 11 11 11 0 Leucine Rich repeat F-box PF00646.28 CAM68233.1 - 0.015 14.9 0.1 0.092 12.4 0.0 2.4 2 0 0 2 2 2 0 F-box domain LRR_7 PF13504.1 CAM68233.1 - 0.035 14.2 22.9 7.2 7.2 0.1 8.6 9 1 0 9 9 9 0 Leucine rich repeat DUF3184 PF11380.3 CAM68235.1 - 0.00025 19.1 0.1 0.0027 15.7 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3184) DUF3184 PF11380.3 CAM68236.1 - 0.00025 19.1 0.1 0.0027 15.7 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3184) CH PF00307.26 CAM68237.1 - 0.0055 16.7 0.4 0.027 14.5 0.3 2.1 1 1 0 1 1 1 1 Calponin homology (CH) domain DUF3450 PF11932.3 CAM68238.1 - 0.0045 16.2 3.2 0.0045 16.2 2.2 4.3 4 1 0 4 4 4 1 Protein of unknown function (DUF3450) DivIC PF04977.10 CAM68238.1 - 1.1 8.8 28.4 0.031 13.7 0.5 5.4 5 1 0 5 5 5 0 Septum formation initiator DUF641 PF04859.7 CAM68238.1 - 1.5 8.5 18.7 0.1 12.3 1.5 3.9 3 1 0 3 3 3 0 Plant protein of unknown function (DUF641) DUF972 PF06156.8 CAM68238.1 - 1.9 8.8 23.8 1.9 8.8 1.6 5.2 4 1 1 5 5 5 0 Protein of unknown function (DUF972) IncA PF04156.9 CAM68238.1 - 8.4 5.9 37.6 0.89 9.1 4.9 4.7 4 1 0 4 4 4 0 IncA protein HALZ PF02183.13 CAM68238.1 - 9.1 6.0 12.2 1.1 9.0 0.8 4.5 4 0 0 4 4 4 0 Homeobox associated leucine zipper DUF2730 PF10805.3 CAM68238.1 - 9.7 5.9 8.6 14 5.4 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) IncA PF04156.9 CAM68239.1 - 0.0045 16.6 14.2 0.0045 16.6 9.9 5.8 3 1 1 5 5 5 3 IncA protein Pox_A_type_inc PF04508.7 CAM68239.1 - 0.1 12.4 0.1 0.1 12.4 0.1 6.3 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat HALZ PF02183.13 CAM68239.1 - 1.5 8.6 28.2 0.45 10.2 0.5 7.5 7 2 2 9 9 9 0 Homeobox associated leucine zipper DUF2422 PF10337.4 CAM68239.1 - 4.3 6.0 15.1 13 4.4 10.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Nrf1_activ_bdg PF10492.4 CAM68239.1 - 4.7 7.7 5.8 3.6 8.1 0.2 3.0 3 0 0 3 3 3 0 Nrf1 activator activation site binding domain BRCA-2_OB3 PF09104.5 CAM68240.1 - 0.007 16.1 0.1 0.033 14.0 0.0 2.1 2 0 0 2 2 2 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 Amdo_NSP PF12475.3 CAM68241.1 - 0.23 11.4 3.5 12 5.8 0.1 3.4 3 1 0 3 3 3 0 Amdovirus non-structural protein DUF1900 PF08954.6 CAM68242.1 - 6.7e-39 132.5 0.0 1.1e-38 131.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) WD40 PF00400.27 CAM68242.1 - 9.4e-14 50.6 2.2 1.4e-05 24.7 0.1 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF1899 PF08953.6 CAM68242.1 - 2.4e-07 30.2 0.1 4.3e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) Ribosomal_S9 PF00380.14 CAM68243.1 - 0.00015 22.0 0.0 0.0003 21.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 UPF0546 PF10639.4 CAM68244.1 - 6.4e-38 129.0 1.9 7.4e-38 128.8 1.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 EamA PF00892.15 CAM68244.1 - 1.6e-05 24.9 2.7 1.6e-05 24.9 1.9 1.6 2 0 0 2 2 2 1 EamA-like transporter family His_Phos_2 PF00328.17 CAM68245.1 - 1.2e-25 90.5 0.1 3.6e-25 89.0 0.1 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Methyltransf_5 PF01795.14 CAM68246.1 - 1.1e-29 103.7 0.0 1.6e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 MraW methylase family Methyltransf_26 PF13659.1 CAM68246.1 - 1.7e-05 24.7 0.1 9.1e-05 22.4 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAM68246.1 - 3.5e-05 23.4 0.0 0.00072 19.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAM68246.1 - 0.0012 19.4 0.0 0.025 15.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CAM68246.1 - 0.017 14.4 0.0 0.16 11.3 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain SIR2 PF02146.12 CAM68247.1 - 3.7e-35 121.2 0.0 8.3e-34 116.8 0.0 2.1 1 1 0 1 1 1 1 Sir2 family Cpn60_TCP1 PF00118.19 CAM68248.1 - 8.6e-150 499.5 3.1 9.9e-150 499.3 2.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Spore_coat_CotO PF14153.1 CAM68249.1 - 0.029 13.8 0.3 0.035 13.5 0.2 1.1 1 0 0 1 1 1 0 Spore coat protein CotO PPR_2 PF13041.1 CAM68250.1 - 9.5e-06 25.4 0.0 2.7e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 PPR repeat family PPR_1 PF12854.2 CAM68250.1 - 0.00011 21.5 0.0 0.00024 20.4 0.0 1.6 1 0 0 1 1 1 1 PPR repeat PPR_3 PF13812.1 CAM68250.1 - 0.00084 19.4 0.0 0.0042 17.2 0.0 2.3 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR PF01535.15 CAM68250.1 - 0.0021 17.9 0.6 0.0065 16.3 0.1 2.1 2 0 0 2 2 2 1 PPR repeat DUF3250 PF11618.3 CAM68251.1 - 1.3e-32 112.1 1.0 1.3e-32 112.1 0.7 3.3 3 1 1 4 4 4 1 Protein of unknown function (DUF3250) DUF972 PF06156.8 CAM68251.1 - 0.58 10.5 28.7 0.27 11.5 0.4 4.9 2 1 3 5 5 5 0 Protein of unknown function (DUF972) HCMV_UL139 PF12507.3 CAM68251.1 - 2.9 8.0 11.1 0.22 11.6 0.2 3.4 2 1 1 3 3 3 0 Human Cytomegalovirus UL139 protein RICTOR_M PF14666.1 CAM68252.1 - 7.1e-56 188.7 0.0 4.5e-55 186.1 0.0 2.1 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_N PF14664.1 CAM68252.1 - 5.4e-15 54.8 1.0 2.5e-12 46.0 0.0 2.8 3 0 0 3 3 3 2 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.1 CAM68252.1 - 6e-08 32.6 0.3 3.1e-07 30.3 0.2 2.3 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 CAM68252.1 - 0.0023 17.8 0.2 0.045 13.6 0.0 3.2 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 DUF4455 PF14643.1 CAM68252.1 - 0.093 11.3 2.8 0.15 10.6 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) XPG_I PF00867.13 CAM68255.1 - 1e-21 76.7 0.2 7e-19 67.6 0.1 2.6 2 0 0 2 2 2 2 XPG I-region XPG_N PF00752.12 CAM68255.1 - 6.8e-15 55.1 0.1 3.1e-06 27.3 0.0 2.6 3 0 0 3 3 3 2 XPG N-terminal domain Lentiviral_Tat PF02998.9 CAM68256.1 - 0.024 14.4 0.1 0.073 12.8 0.0 1.7 1 0 0 1 1 1 0 Lentiviral Tat protein FA_hydroxylase PF04116.8 CAM68258.1 - 4.1e-13 49.7 22.3 4.1e-13 49.7 15.5 2.7 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily COX14 PF14880.1 CAM68258.1 - 0.24 11.0 2.0 0.25 10.9 0.3 1.9 2 0 0 2 2 2 0 Cytochrome oxidase c assembly RSN1_TM PF13967.1 CAM68258.1 - 0.27 10.8 0.1 0.27 10.8 0.1 2.9 2 1 1 3 3 3 0 Late exocytosis, associated with Golgi transport Dynein_heavy PF03028.10 CAM68259.1 - 3.1e-199 663.5 0.0 7e-199 662.3 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 CAM68259.1 - 2.6e-124 414.8 4.7 2.6e-124 414.8 3.3 3.9 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CAM68259.1 - 1.5e-96 322.4 0.0 4.8e-96 320.7 0.0 1.9 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 DHC_N1 PF08385.7 CAM68259.1 - 2.1e-77 260.8 0.0 2.1e-77 260.8 0.0 4.2 5 2 0 5 5 4 1 Dynein heavy chain, N-terminal region 1 AAA_8 PF12780.2 CAM68259.1 - 1.3e-66 224.3 0.0 3.5e-66 222.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 CAM68259.1 - 1e-52 178.2 0.4 2.7e-52 176.8 0.1 1.9 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 CAM68259.1 - 3.4e-47 160.7 0.1 9.7e-47 159.3 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 MT PF12777.2 CAM68259.1 - 4.3e-41 140.7 15.2 9.7e-41 139.6 10.5 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 CAM68259.1 - 6.4e-26 90.7 0.2 1.3e-07 31.4 0.0 5.8 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA PF00004.24 CAM68259.1 - 4e-06 27.0 0.1 0.36 11.0 0.0 4.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CAM68259.1 - 0.00052 20.8 0.2 5.2 7.9 0.0 5.2 5 0 0 5 5 4 1 AAA domain AAA_18 PF13238.1 CAM68259.1 - 0.0058 16.9 0.8 35 4.7 0.0 4.9 4 0 0 4 4 4 0 AAA domain AAA_22 PF13401.1 CAM68259.1 - 0.015 15.4 12.3 0.81 9.8 0.0 6.2 7 0 0 7 7 6 0 AAA domain RNA_helicase PF00910.17 CAM68259.1 - 0.018 15.2 0.1 6.6 6.9 0.0 3.3 3 0 0 3 3 3 0 RNA helicase AAA_19 PF13245.1 CAM68259.1 - 0.27 11.0 5.3 3.7 7.3 0.4 3.6 3 0 0 3 3 3 0 Part of AAA domain YceI PF04264.8 CAM68260.1 - 1.6e-10 41.1 0.0 1.9e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 YceI-like domain DNA_pol_B PF00136.16 CAM68262.2 - 7.9e-77 258.9 0.0 1.2e-76 258.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CAM68262.2 - 6.3e-07 28.5 0.0 0.0026 16.6 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 CAM68262.2 - 0.00017 21.4 0.1 0.00089 19.2 0.0 2.2 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta Radical_SAM PF04055.16 CAM68264.1 - 2.6e-14 53.7 0.0 7.3e-14 52.2 0.0 1.8 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 CAM68264.1 - 9.2e-08 32.0 0.4 2.3e-07 30.7 0.3 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Mito_carr PF00153.22 CAM68266.1 - 4.6e-38 128.8 0.2 6.7e-16 57.7 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Host_attach PF10116.4 CAM68266.1 - 0.12 12.6 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein required for attachment to host cells DEAD PF00270.24 CAM68267.1 - 1e-12 47.8 0.0 4.6e-11 42.5 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM68267.1 - 4.4e-12 45.7 0.0 8.7e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HHH_5 PF14520.1 CAM68267.1 - 2.7e-05 24.2 0.1 0.00011 22.3 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix domain Cg6151-P PF10233.4 CAM68268.1 - 0.025 14.5 6.1 0.038 13.9 4.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein CG6151-P DUF948 PF06103.6 CAM68268.1 - 0.22 11.3 3.0 4.3 7.2 0.0 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Mog1 PF04603.7 CAM68269.1 - 4e-24 85.1 0.0 1e-19 70.9 0.0 2.1 1 1 1 2 2 2 2 Ran-interacting Mog1 protein Fer2_3 PF13085.1 CAM68271.1 - 1.9e-31 108.1 0.1 6.4e-31 106.4 0.0 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPR_21 PF09976.4 CAM68271.1 - 0.0062 16.4 1.1 0.012 15.5 0.8 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat Fer2 PF00111.22 CAM68271.1 - 0.009 15.7 2.2 0.01 15.5 0.5 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Acetone_carb_G PF08882.6 CAM68271.1 - 0.047 13.7 0.0 0.097 12.6 0.0 1.6 1 0 0 1 1 1 0 Acetone carboxylase gamma subunit TPR_6 PF13174.1 CAM68271.1 - 0.33 11.4 2.2 0.36 11.3 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 CAM68271.1 - 0.66 10.3 4.5 0.33 11.3 1.3 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-DHHC PF01529.15 CAM68272.1 - 1.6e-35 122.0 11.5 1.6e-35 122.0 8.0 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF1282 PF06930.7 CAM68272.1 - 0.016 14.8 14.0 0.02 14.5 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) zf-DHHC PF01529.15 CAM68273.1 - 7.8e-34 116.5 2.1 7.8e-34 116.5 1.5 2.2 3 1 0 3 3 3 1 DHHC palmitoyltransferase TALPID3 PF15324.1 CAM68273.1 - 0.056 10.7 0.1 0.082 10.2 0.1 1.1 1 0 0 1 1 1 0 Hedgehog signalling target zf-DHHC PF01529.15 CAM68274.1 - 1.1e-25 90.0 17.7 1.1e-25 90.0 12.2 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase PTPlike_phytase PF14566.1 CAM68275.1 - 1.9e-108 358.9 0.4 5e-41 140.2 0.0 3.6 3 0 0 3 3 3 3 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 CAM68275.1 - 0.002 18.3 2.1 3.6 7.8 0.0 3.7 4 0 0 4 4 4 2 Tyrosine phosphatase family Y_phosphatase PF00102.22 CAM68275.1 - 0.12 11.6 0.0 13 5.0 0.0 3.0 3 0 0 3 3 3 0 Protein-tyrosine phosphatase ADK PF00406.17 CAM68276.1 - 2.7e-07 30.5 0.0 0.0015 18.3 0.0 2.3 2 0 0 2 2 2 2 Adenylate kinase AAA_33 PF13671.1 CAM68276.1 - 0.00015 21.6 0.0 0.00031 20.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CAM68276.1 - 0.0059 16.5 0.0 0.013 15.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CAM68276.1 - 0.0061 16.5 1.0 0.011 15.6 0.4 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 CAM68276.1 - 0.0061 16.2 2.4 0.023 14.4 1.3 2.4 1 1 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 CAM68276.1 - 0.013 16.3 0.0 0.021 15.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.5 CAM68276.1 - 0.025 13.8 0.3 0.091 11.9 0.0 2.0 2 1 0 2 2 2 0 Chromatin associated protein KTI12 AAA PF00004.24 CAM68276.1 - 0.034 14.3 0.2 0.25 11.5 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 CAM68276.1 - 0.035 13.2 0.1 0.082 11.9 0.0 1.6 1 1 0 1 1 1 0 Zeta toxin AAA_5 PF07728.9 CAM68276.1 - 0.035 13.8 0.1 5.6 6.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Ocular_alb PF02101.10 CAM68277.1 - 0.0085 14.7 0.2 0.011 14.3 0.1 1.1 1 0 0 1 1 1 1 Ocular albinism type 1 protein Methyltransf_26 PF13659.1 CAM68277.1 - 0.017 15.1 0.1 0.038 14.0 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 CAM68277.1 - 0.12 12.7 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain B9-C2 PF07162.6 CAM68278.1 - 7.6e-25 87.6 0.0 1.1e-24 87.1 0.0 1.2 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Mt_ATP-synt_B PF05405.9 CAM68279.1 - 0.21 11.0 1.3 0.29 10.5 0.9 1.1 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) zf-rbx1 PF12678.2 CAM68281.1 - 3.9e-13 49.3 4.3 6.6e-13 48.5 3.0 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CAM68281.1 - 1.1e-10 41.1 10.1 3.6e-09 36.2 7.0 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CAM68281.1 - 8.4e-07 28.9 7.1 5.4e-06 26.3 3.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CAM68281.1 - 8.7e-07 28.4 6.5 1.8e-06 27.4 4.5 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAM68281.1 - 2.8e-05 23.7 6.1 6.8e-05 22.5 4.1 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 CAM68281.1 - 0.00026 20.7 5.2 0.0011 18.8 3.6 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 CAM68281.1 - 0.0005 19.6 10.0 0.0022 17.6 6.1 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 CAM68281.1 - 0.057 12.9 2.4 0.12 11.8 1.6 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.2 CAM68281.1 - 0.42 10.6 6.8 0.4 10.7 3.0 2.0 2 0 0 2 2 2 0 RING-variant domain GAGA PF09237.6 CAM68281.1 - 2.3 7.8 5.7 28 4.3 0.5 3.1 3 0 0 3 3 3 0 GAGA factor FANCL_C PF11793.3 CAM68281.1 - 2.7 8.0 7.0 19 5.3 4.9 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 CAM68281.1 - 5.8 6.7 7.8 5.1 6.9 2.8 2.7 1 1 1 2 2 2 0 RING-type zinc-finger V-SNARE PF05008.10 CAM68282.1 - 9.3e-07 28.9 1.5 0.00014 21.9 0.0 3.3 3 1 1 4 4 4 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.8 CAM68282.1 - 5.4e-06 26.0 1.4 1.3e-05 24.7 0.2 2.0 2 0 0 2 2 2 1 Sec20 V-SNARE_C PF12352.3 CAM68282.1 - 0.0051 16.8 3.4 0.0051 16.8 2.4 2.5 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Syntaxin-6_N PF09177.6 CAM68282.1 - 0.026 14.8 1.1 3.1 8.2 0.0 3.2 2 1 1 3 3 3 0 Syntaxin 6, N-terminal EMP24_GP25L PF01105.19 CAM68282.1 - 0.036 13.8 0.5 1.8 8.2 0.2 2.1 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF3753 PF12575.3 CAM68282.1 - 0.05 13.3 0.4 0.05 13.3 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) DUF3391 PF11871.3 CAM68282.1 - 0.11 12.7 2.1 1.7 8.8 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3391) Laminin_I PF06008.9 CAM68282.1 - 0.2 10.9 7.2 0.092 12.0 2.6 1.9 2 0 0 2 2 2 0 Laminin Domain I BRE1 PF08647.6 CAM68282.1 - 0.26 11.2 2.0 2.4 8.2 0.1 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase V-SNARE PF05008.10 CAM68283.1 - 8e-12 45.1 0.2 5.4e-11 42.4 0.0 2.4 2 1 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 CAM68283.1 - 8.1e-07 29.0 0.5 2.2e-06 27.6 0.3 1.7 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 CAM68283.1 - 0.00021 20.9 2.0 0.00048 19.7 0.9 1.9 2 0 0 2 2 2 1 Sec20 Unstab_antitox PF09720.5 CAM68283.1 - 0.00075 19.1 0.1 0.0017 17.9 0.1 1.6 1 0 0 1 1 1 1 Putative addiction module component CCDC155 PF14662.1 CAM68283.1 - 0.00086 18.9 5.6 0.032 13.8 0.7 2.2 2 0 0 2 2 2 2 Coiled-coil region of CCDC155 HXXSHH PF07586.6 CAM68283.1 - 0.013 14.4 0.6 0.073 11.9 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1552) Baculo_11_kDa PF06143.6 CAM68283.1 - 0.052 12.9 0.1 0.096 12.0 0.1 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF4140 PF13600.1 CAM68283.1 - 0.075 13.4 0.8 0.075 13.4 0.5 2.4 3 0 0 3 3 2 0 N-terminal domain of unknown function (DUF4140) DUF3357 PF11837.3 CAM68283.1 - 0.089 12.6 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DUF2116 PF09889.4 CAM68283.1 - 0.21 11.4 0.6 0.35 10.6 0.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF1515 PF07439.6 CAM68283.1 - 0.32 10.8 2.2 0.64 9.8 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) TMEM154 PF15102.1 CAM68283.1 - 0.37 10.4 3.6 0.64 9.7 2.5 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF883 PF05957.8 CAM68283.1 - 0.44 10.9 9.0 1.4 9.3 1.4 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) IncA PF04156.9 CAM68283.1 - 0.69 9.4 6.8 4.2 6.9 0.1 3.3 3 1 1 4 4 4 0 IncA protein BRCT PF00533.21 CAM68284.1 - 0.0013 18.7 0.0 0.003 17.6 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain EXOSC1 PF10447.4 CAM68285.1 - 1.4e-10 40.9 0.0 2.6e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 TRAM PF01938.15 CAM68285.1 - 0.006 16.3 0.0 0.025 14.3 0.0 2.0 2 0 0 2 2 2 1 TRAM domain ICE2 PF08426.5 CAM68286.1 - 0.43 9.1 9.2 0.31 9.5 5.2 1.5 1 1 0 1 1 1 0 ICE2 LRR19-TM PF15176.1 CAM68286.1 - 2.1 8.0 5.6 12 5.6 3.9 2.1 1 1 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DUF1418 PF07214.7 CAM68286.1 - 3.5 7.3 5.5 1.4 8.6 1.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1418) DUF3092 PF11289.3 CAM68286.1 - 4.2 6.4 12.7 4.5 6.4 7.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3092) ABC2_membrane_4 PF12730.2 CAM68286.1 - 8.8 5.4 26.9 1.5 7.9 10.2 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein Trichoplein PF13868.1 CAM68288.1 - 4.1e-13 48.4 126.9 4.1e-13 48.4 88.0 2.1 2 0 0 2 2 2 1 Tumour suppressor, Mitostatin Semialdhyde_dh PF01118.19 CAM68288.1 - 4.6 7.5 7.8 1.1 9.5 0.8 2.6 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain TIP41 PF04176.8 CAM68289.1 - 2.1e-18 66.1 0.0 3.6e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 TIP41-like family GAF_2 PF13185.1 CAM68289.1 - 9.2e-10 39.1 0.0 1.6e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 CAM68289.1 - 9.5e-08 32.3 0.0 1.9e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 CAM68289.1 - 1.5e-05 25.0 0.0 2.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 GAF domain LRR_4 PF12799.2 CAM68290.1 - 4.2e-05 23.0 2.1 0.024 14.2 0.0 2.9 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM68290.1 - 0.1 12.3 2.3 8.4 6.2 0.0 2.6 2 1 0 2 2 2 0 Leucine rich repeat MYCBPAP PF14646.1 CAM68290.1 - 0.55 8.8 2.4 0.8 8.3 1.6 1.2 1 0 0 1 1 1 0 MYCBP-associated protein family LRR_7 PF13504.1 CAM68290.1 - 0.69 10.3 3.7 36 5.1 0.0 4.1 4 2 0 4 4 4 0 Leucine rich repeat CobT PF06213.7 CAM68290.1 - 1.2 8.1 9.9 1.4 7.9 6.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.7 CAM68290.1 - 2 6.2 12.0 2.3 6.0 8.3 1.1 1 0 0 1 1 1 0 Nop14-like family Ala_racemase_N PF01168.15 CAM68291.1 - 1.9e-42 145.2 0.0 2.3e-42 144.9 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain LRR_4 PF12799.2 CAM68292.1 - 4e-12 45.4 7.0 0.0027 17.2 0.2 5.4 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM68292.1 - 1.2e-11 44.1 3.6 0.066 12.9 0.0 4.6 3 2 0 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 CAM68292.1 - 3.5e-09 35.4 5.5 0.95 9.7 0.0 7.0 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_6 PF13516.1 CAM68292.1 - 1.4e-06 27.7 6.0 0.44 10.7 0.0 5.9 6 0 0 6 6 6 2 Leucine Rich repeat PMP1_2 PF08114.6 CAM68292.1 - 0.045 13.2 0.1 0.086 12.3 0.1 1.4 1 0 0 1 1 1 0 ATPase proteolipid family LRR_7 PF13504.1 CAM68292.1 - 0.23 11.8 18.6 8.3 7.1 0.2 6.5 7 1 0 7 7 7 0 Leucine rich repeat V_ATPase_I PF01496.14 CAM68294.1 - 7.4e-216 718.5 11.9 1.4e-213 711.0 8.2 2.0 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family FIST_C PF10442.4 CAM68294.1 - 0.039 13.8 0.0 0.092 12.6 0.0 1.6 1 0 0 1 1 1 0 FIST C domain DUF972 PF06156.8 CAM68294.1 - 0.056 13.7 0.6 0.5 10.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF948 PF06103.6 CAM68294.1 - 0.068 13.0 0.4 8.9 6.2 0.1 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DegS PF05384.6 CAM68294.1 - 0.082 12.1 3.4 4.5 6.4 0.0 2.9 3 0 0 3 3 3 0 Sensor protein DegS UbiA PF01040.13 CAM68295.1 - 1.7e-29 102.8 20.2 2.9e-29 102.0 14.0 1.4 1 0 0 1 1 1 1 UbiA prenyltransferase family BCDHK_Adom3 PF10436.4 CAM68296.1 - 1.9e-34 118.5 0.0 3.2e-34 117.8 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CAM68296.1 - 0.012 15.2 0.0 0.059 13.1 0.0 2.1 2 1 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FerB PF08150.7 CAM68296.1 - 0.017 15.1 0.0 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 FerB (NUC096) domain ANTH PF07651.11 CAM68297.1 - 3.2e-24 85.1 0.2 5.2e-24 84.4 0.2 1.3 1 1 0 1 1 1 1 ANTH domain ENTH PF01417.15 CAM68297.1 - 0.01 15.6 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 0 ENTH domain DUF1043 PF06295.7 CAM68297.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Spectrin PF00435.16 CAM68298.1 - 0.034 14.4 0.5 0.047 13.9 0.3 1.1 1 0 0 1 1 1 0 Spectrin repeat Ribosomal_L22 PF00237.14 CAM68299.1 - 2.7e-30 104.4 0.2 3.3e-30 104.1 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF4616 PF15394.1 CAM68300.1 - 0.021 13.8 0.0 0.041 12.8 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4616) DnaJ PF00226.26 CAM68302.1 - 0.034 13.8 0.0 0.11 12.2 0.0 1.9 1 0 0 1 1 1 0 DnaJ domain zf-RING_2 PF13639.1 CAM68303.2 - 3.6e-10 39.4 4.6 3.6e-10 39.4 3.2 4.5 4 1 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.1 CAM68303.2 - 4.4e-05 23.4 2.2 4.4e-05 23.4 1.6 4.1 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CAM68303.2 - 5.7e-05 22.6 2.2 5.7e-05 22.6 1.5 4.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CAM68303.2 - 0.00029 20.8 1.2 0.00029 20.8 0.8 2.9 2 1 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CAM68303.2 - 0.0015 18.2 4.9 0.0015 18.2 3.4 4.6 4 1 1 5 5 5 1 zinc-RING finger domain Nuc_sug_transp PF04142.10 CAM68304.1 - 2e-51 174.4 7.0 2e-51 174.4 4.8 1.7 2 0 0 2 2 2 1 Nucleotide-sugar transporter EmrE PF13536.1 CAM68304.1 - 0.00056 20.0 22.5 0.0019 18.3 4.1 3.0 2 1 0 2 2 2 2 Multidrug resistance efflux transporter UAA PF08449.6 CAM68304.1 - 0.013 14.3 10.2 0.025 13.4 7.1 1.5 1 0 0 1 1 1 0 UAA transporter family TPT PF03151.11 CAM68304.1 - 2.1 7.9 19.4 5.7 6.5 0.7 3.1 2 1 0 2 2 2 0 Triose-phosphate Transporter family DUF3184 PF11380.3 CAM68306.2 - 1.5e-93 314.0 21.1 4.8e-52 176.8 6.0 4.9 3 1 1 4 4 4 4 Protein of unknown function (DUF3184) DUF3184 PF11380.3 CAM68307.1 - 1.7e-71 241.1 16.7 1e-51 175.7 6.5 4.0 2 1 1 3 3 3 3 Protein of unknown function (DUF3184) ThiF PF00899.16 CAM68308.1 - 2.6e-35 121.2 0.8 3.9e-35 120.6 0.5 1.2 1 0 0 1 1 1 1 ThiF family Response_reg PF00072.19 CAM68308.1 - 0.0003 20.7 0.0 0.0005 20.0 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Methyltransf_5 PF01795.14 CAM68308.1 - 0.07 12.3 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 MraW methylase family adh_short PF00106.20 CAM68308.1 - 0.081 12.8 0.7 0.21 11.4 0.5 1.8 1 1 0 1 1 1 0 short chain dehydrogenase F420_oxidored PF03807.12 CAM68308.1 - 0.083 13.3 0.2 0.24 11.8 0.0 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 CAM68308.1 - 0.12 12.6 0.3 0.29 11.3 0.2 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 CAM68308.1 - 0.15 12.1 0.7 0.34 11.0 0.5 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Kelch_4 PF13418.1 CAM68310.1 - 8.3e-31 105.5 3.2 6.7e-08 32.1 0.0 7.2 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 CAM68310.1 - 2.9e-24 84.5 0.3 3.4e-08 33.2 0.0 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 CAM68310.1 - 1.2e-19 69.5 0.3 0.0024 17.9 0.0 7.0 5 1 2 7 7 7 4 Kelch motif Kelch_3 PF13415.1 CAM68310.1 - 6.7e-15 54.7 15.7 3.8e-06 26.9 0.1 9.1 10 0 0 10 10 10 4 Galactose oxidase, central domain Kelch_2 PF07646.10 CAM68310.1 - 1e-09 37.7 0.1 0.0088 15.7 0.0 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 CAM68310.1 - 7.7e-07 28.5 0.0 0.00086 18.8 0.0 4.6 4 0 0 4 4 4 1 Kelch motif LRR_4 PF12799.2 CAM68311.1 - 1.6e-64 212.6 56.3 2.5e-08 33.3 0.2 14.0 12 2 2 14 14 14 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM68311.1 - 2.7e-43 145.5 63.4 2.1e-08 33.7 0.6 9.9 6 3 5 11 11 11 10 Leucine rich repeat LRR_9 PF14580.1 CAM68311.1 - 2e-23 82.8 15.7 5.7e-06 25.9 0.2 7.3 5 2 2 7 7 7 6 Leucine-rich repeat LRR_1 PF00560.28 CAM68311.1 - 2.4e-17 60.2 66.2 0.21 11.7 0.7 19.9 21 1 1 22 22 22 10 Leucine Rich Repeat LRR_7 PF13504.1 CAM68311.1 - 7.6e-12 43.3 67.3 1.5 9.3 0.4 20.0 20 1 1 21 21 21 7 Leucine rich repeat LRR_6 PF13516.1 CAM68311.1 - 2.4e-07 30.0 44.4 6.3 7.1 0.2 17.1 15 3 3 18 18 18 2 Leucine Rich repeat Spectrin PF00435.16 CAM68313.1 - 0.0021 18.3 8.8 0.0021 18.3 6.1 4.8 5 2 1 6 6 6 1 Spectrin repeat DUF1664 PF07889.7 CAM68313.1 - 0.025 14.3 0.2 0.025 14.3 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DnaJ PF00226.26 CAM68314.1 - 4.7e-15 55.0 2.3 1e-14 53.9 1.6 1.6 1 0 0 1 1 1 1 DnaJ domain ChaC PF04752.7 CAM68315.1 - 0.092 12.6 0.1 0.16 11.9 0.0 1.4 1 1 0 1 1 1 0 ChaC-like protein TRM13 PF05206.9 CAM68316.1 - 4.5e-14 52.3 0.2 8.5e-07 28.4 0.1 2.2 2 0 0 2 2 2 2 Methyltransferase TRM13 Methyltransf_32 PF13679.1 CAM68316.1 - 1.1e-07 31.6 0.0 2.2e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 CAM68316.1 - 0.041 13.0 0.2 0.077 12.1 0.1 1.4 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_23 PF13489.1 CAM68316.1 - 0.07 12.8 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain TRM13 PF05206.9 CAM68317.1 - 2.6e-17 62.9 0.0 4.9e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase TRM13 Methyltransf_32 PF13679.1 CAM68317.1 - 8.1e-07 28.8 1.5 1.4e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.13 CAM68317.1 - 0.049 12.8 0.2 0.09 11.9 0.1 1.4 1 0 0 1 1 1 0 O-methyltransferase DUF3261 PF11659.3 CAM68317.1 - 0.059 12.9 1.7 0.23 11.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3261) Methyltransf_23 PF13489.1 CAM68317.1 - 0.094 12.4 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Npa1 PF11707.3 CAM68320.1 - 1.1e-06 27.8 0.0 3.1e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal MOR2-PAG1_N PF14222.1 CAM68320.1 - 0.0025 16.5 0.1 0.0047 15.6 0.1 1.4 1 0 0 1 1 1 1 Cell morphogenesis N-terminal SNF2_N PF00176.18 CAM68321.2 - 5.7e-37 127.1 0.0 8.5e-37 126.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CAM68321.2 - 1.8e-09 37.3 0.0 2.9e-08 33.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAM68321.2 - 2.7e-07 30.2 0.0 5.4e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CAM68321.2 - 1.5e-05 24.9 0.0 0.00054 19.8 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UCH PF00443.24 CAM68322.2 - 7.7e-47 159.6 0.0 1.2e-46 159.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CAM68322.2 - 3.9e-11 42.9 0.0 1e-10 41.5 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ATP-synt_C PF00137.16 CAM68323.1 - 4.1e-16 58.6 13.8 4.1e-16 58.6 9.6 1.6 2 0 0 2 2 2 1 ATP synthase subunit C Tetraspannin PF00335.15 CAM68323.1 - 4.8 6.3 8.3 6 6.0 5.7 1.2 1 0 0 1 1 1 0 Tetraspanin family Kinesin PF00225.18 CAM68324.1 - 1.7e-91 306.3 0.0 2.2e-91 306.0 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Peptidase_C97 PF05903.9 CAM68325.1 - 1.4e-29 102.8 0.0 9.2e-28 96.9 0.0 2.2 2 0 0 2 2 2 1 PPPDE putative peptidase domain LRAT PF04970.8 CAM68325.1 - 0.0078 16.1 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 Lecithin retinol acyltransferase DUF2607 PF10795.4 CAM68325.1 - 0.043 13.6 0.2 0.13 12.0 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2607) YdjO PF14169.1 CAM68325.1 - 0.21 11.0 1.6 0.46 9.9 1.1 1.5 1 0 0 1 1 1 0 Cold-inducible protein YdjO ACDC PF14733.1 CAM68326.1 - 0.079 13.0 0.2 0.54 10.4 0.1 2.4 2 0 0 2 2 2 0 AP2-coincident C-terminal Pkinase PF00069.20 CAM68327.2 - 1.3e-33 116.2 0.0 2.4e-33 115.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM68327.2 - 4.1e-10 39.1 0.0 8.4e-06 25.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase ACC_epsilon PF13822.1 CAM68327.2 - 0.0038 17.5 2.4 0.0038 17.5 1.7 2.8 2 0 0 2 2 2 1 Acyl-CoA carboxylase epsilon subunit Sugar_tr PF00083.19 CAM68328.1 - 1.5e-124 416.0 37.3 1.7e-124 415.8 25.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAM68328.1 - 2.2e-30 105.5 81.3 5.4e-29 101.0 29.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CAM68328.1 - 4e-07 28.7 31.8 0.00011 20.8 3.3 3.3 1 1 2 3 3 3 3 MFS/sugar transport protein DUF523 PF04463.7 CAM68331.1 - 4.3e-14 52.4 0.0 2.8e-07 30.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF523) zf-Tim10_DDP PF02953.10 CAM68332.1 - 1.3e-05 24.3 0.6 1.7e-05 24.0 0.4 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger SRP54 PF00448.17 CAM68333.1 - 4.3e-74 248.2 1.2 7.8e-74 247.3 0.8 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 CAM68333.1 - 3.5e-24 85.0 2.4 3.5e-24 85.0 1.7 4.8 3 1 0 4 4 2 1 Signal peptide binding domain SRP54_N PF02881.14 CAM68333.1 - 6.4e-13 48.6 1.1 2e-12 46.9 0.8 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 CAM68333.1 - 1.2e-08 34.6 0.4 3.5e-08 33.0 0.3 1.8 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 CAM68333.1 - 2.8e-06 27.2 0.1 8.3e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain CbiA PF01656.18 CAM68333.1 - 5.2e-06 25.9 1.0 1.4e-05 24.5 0.1 2.1 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 CAM68333.1 - 0.00012 22.0 0.0 0.38 10.6 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 CAM68333.1 - 0.00013 22.1 0.3 0.0031 17.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 CAM68333.1 - 0.00028 20.6 1.8 0.0018 18.0 0.2 2.7 2 1 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 CAM68333.1 - 0.00059 18.9 0.0 0.0013 17.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Methyltransf_24 PF13578.1 CAM68333.1 - 0.0025 18.6 0.0 0.013 16.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain ArgK PF03308.11 CAM68333.1 - 0.0037 16.0 0.1 0.018 13.8 0.0 2.1 1 1 0 1 1 1 1 ArgK protein SRPRB PF09439.5 CAM68333.1 - 0.0085 15.3 1.2 2.3 7.4 0.8 2.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit APS_kinase PF01583.15 CAM68333.1 - 0.011 15.4 0.0 0.024 14.2 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_30 PF13604.1 CAM68333.1 - 0.016 14.8 3.0 0.017 14.7 0.1 2.5 3 1 0 3 3 3 0 AAA domain AAA_16 PF13191.1 CAM68333.1 - 0.019 14.9 0.0 0.047 13.6 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 CAM68333.1 - 0.019 14.3 0.0 0.063 12.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CAM68333.1 - 0.035 14.9 0.0 0.083 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 CAM68333.1 - 0.041 13.4 0.7 0.31 10.5 0.5 2.4 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein KaiC PF06745.8 CAM68333.1 - 0.12 11.4 2.4 0.36 9.9 0.2 2.5 2 1 0 2 2 2 0 KaiC Dynamin_N PF00350.18 CAM68333.1 - 0.12 12.1 1.3 0.25 11.1 0.0 2.0 2 0 0 2 2 2 0 Dynamin family Response_reg PF00072.19 CAM68333.1 - 0.22 11.5 2.3 0.27 11.2 0.0 2.4 3 0 0 3 3 2 0 Response regulator receiver domain CENP-F_leu_zip PF10473.4 CAM68335.1 - 0.0032 17.3 4.6 0.0032 17.3 3.2 1.8 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.3 CAM68335.1 - 0.014 15.1 2.8 0.014 15.1 1.9 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding PV-1 PF06637.6 CAM68335.1 - 0.014 14.0 2.7 0.021 13.4 1.9 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) ADIP PF11559.3 CAM68335.1 - 0.33 10.8 5.5 0.12 12.3 0.8 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding HrpB7 PF09486.5 CAM68335.1 - 0.37 10.6 12.9 0.047 13.6 5.2 2.0 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DivIC PF04977.10 CAM68335.1 - 9.4 5.7 7.4 1.7 8.2 2.3 1.8 2 0 0 2 2 2 0 Septum formation initiator SNF2_N PF00176.18 CAM68336.1 - 3.2e-61 206.7 0.0 5.1e-61 206.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CAM68336.1 - 1.8e-13 50.1 0.0 4.6e-13 48.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAM68336.1 - 7.1e-12 45.1 0.0 1.9e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CAM68336.1 - 0.00055 19.8 0.0 0.0017 18.2 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Malic_M PF03949.10 CAM68337.1 - 8.4e-75 251.6 0.3 1.1e-74 251.2 0.2 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 CAM68337.1 - 1.6e-67 226.6 0.0 4.8e-67 225.0 0.0 1.8 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain Malic_M PF03949.10 CAM68338.1 - 2.7e-76 256.4 0.1 3.8e-76 256.0 0.1 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 CAM68338.1 - 6.4e-68 227.9 0.0 9.2e-68 227.3 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF2235 PF09994.4 CAM68338.1 - 0.19 11.0 0.1 5.6 6.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) PTS_2-RNA PF01885.11 CAM68342.1 - 3.3e-52 176.5 0.1 4.8e-52 175.9 0.1 1.2 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family RNase_T PF00929.19 CAM68342.1 - 3.2e-16 60.0 0.0 6.9e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 Exonuclease Syja_N PF02383.13 CAM68343.1 - 6.6e-70 235.3 0.0 9.4e-70 234.8 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain DUF547 PF04784.9 CAM68343.1 - 0.18 11.7 0.0 0.61 9.9 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF547 Ax_dynein_light PF10211.4 CAM68345.1 - 3e-78 262.0 5.6 3.5e-78 261.8 3.9 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain Filament PF00038.16 CAM68345.1 - 7.9e-05 22.2 8.6 0.00056 19.4 2.3 2.0 1 1 1 2 2 2 2 Intermediate filament protein ERM PF00769.14 CAM68345.1 - 0.00024 20.7 8.7 0.00036 20.1 6.0 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family APG6 PF04111.7 CAM68345.1 - 0.00039 19.5 4.7 0.00055 19.0 3.3 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 OmpH PF03938.9 CAM68345.1 - 0.0016 18.3 2.0 0.0023 17.8 1.4 1.2 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Syntaxin-6_N PF09177.6 CAM68345.1 - 0.0031 17.8 4.2 0.0068 16.7 2.9 1.6 1 0 0 1 1 1 1 Syntaxin 6, N-terminal Mei5 PF10376.4 CAM68345.1 - 0.015 14.8 3.7 0.024 14.1 2.5 1.3 1 0 0 1 1 1 0 Double-strand recombination repair protein bZIP_1 PF00170.16 CAM68345.1 - 0.017 15.0 3.0 0.017 15.0 2.1 1.9 2 0 0 2 2 2 0 bZIP transcription factor Spc24 PF08286.6 CAM68345.1 - 0.033 13.8 4.0 0.057 13.1 2.7 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 HALZ PF02183.13 CAM68345.1 - 0.052 13.2 3.8 0.43 10.3 0.9 3.0 3 0 0 3 3 3 0 Homeobox associated leucine zipper CENP-H PF05837.7 CAM68345.1 - 0.16 12.1 4.7 0.28 11.3 3.3 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF972 PF06156.8 CAM68345.1 - 0.22 11.9 3.8 0.2 12.0 1.8 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF972) Mnd1 PF03962.10 CAM68345.1 - 0.54 9.8 7.4 0.9 9.1 5.1 1.3 1 0 0 1 1 1 0 Mnd1 family Jnk-SapK_ap_N PF09744.4 CAM68345.1 - 1.2 9.0 11.0 2.2 8.2 6.1 2.0 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DivIC PF04977.10 CAM68345.1 - 1.6 8.2 8.8 0.38 10.2 2.8 2.2 2 1 1 3 3 3 0 Septum formation initiator Prefoldin PF02996.12 CAM68345.1 - 2.8 7.5 6.7 4.7 6.8 0.2 2.5 2 1 1 3 3 2 0 Prefoldin subunit IncA PF04156.9 CAM68345.1 - 3.3 7.2 14.8 7.5 6.0 10.1 1.7 1 1 0 1 1 1 0 IncA protein TIM PF00121.13 CAM68346.1 - 1.4e-88 296.0 0.2 1.6e-88 295.9 0.2 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase EMP24_GP25L PF01105.19 CAM68348.1 - 0.00023 20.9 0.0 0.00024 20.8 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF202 PF02656.10 CAM68348.1 - 0.14 12.3 0.1 0.17 12.1 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DNA_pol_A PF00476.15 CAM68350.1 - 3.3e-33 114.8 0.0 2.5e-30 105.3 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase family A P4Ha_N PF08336.6 CAM68350.1 - 0.052 13.3 0.1 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region MCM PF00493.18 CAM68352.1 - 3.1e-119 397.6 0.1 5.8e-119 396.7 0.1 1.4 1 1 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CAM68352.1 - 1.5e-15 57.7 0.0 4.9e-15 56.0 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 CAM68352.1 - 1.7e-07 30.6 0.0 3.6e-06 26.3 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CAM68352.1 - 0.00033 20.2 0.0 0.00088 18.8 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CAM68352.1 - 0.00044 19.9 0.0 0.0011 18.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) PUA PF01472.15 CAM68352.1 - 0.0037 16.9 1.7 0.85 9.3 0.1 2.6 2 0 0 2 2 2 2 PUA domain Sigma54_activat PF00158.21 CAM68352.1 - 0.028 13.9 0.0 0.084 12.3 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain MTS PF05175.9 CAM68353.1 - 0.0012 18.2 0.0 0.0028 17.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 CAM68353.1 - 0.053 13.8 0.0 0.39 11.1 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 CAM68353.1 - 0.068 12.8 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 CAM68353.1 - 0.077 13.5 0.0 0.28 11.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 CAM68353.1 - 0.18 11.4 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF2489 PF10675.4 CAM68354.1 - 0.023 14.3 0.2 0.043 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) RabGAP-TBC PF00566.13 CAM68356.1 - 7.2e-09 35.4 2.3 3e-08 33.4 2.0 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain RFC1 PF08519.7 CAM68360.2 - 1.2e-47 161.5 0.0 4.6e-47 159.6 0.0 1.9 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain AAA PF00004.24 CAM68360.2 - 1.4e-11 44.7 0.0 3.8e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CAM68360.2 - 1.7e-08 33.6 0.0 5.5e-07 28.6 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Zeta_toxin PF06414.7 CAM68360.2 - 0.00038 19.6 0.9 0.0022 17.1 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_14 PF13173.1 CAM68360.2 - 0.00048 20.0 0.0 0.0012 18.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CAM68360.2 - 0.00067 19.8 0.0 0.0023 18.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CAM68360.2 - 0.00075 19.2 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 CAM68360.2 - 0.0012 17.9 0.0 0.002 17.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 CAM68360.2 - 0.0036 17.2 0.2 0.21 11.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CAM68360.2 - 0.0051 16.8 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 CAM68360.2 - 0.012 15.2 0.0 0.012 15.2 0.0 2.8 2 1 1 3 3 3 0 Part of AAA domain AAA_17 PF13207.1 CAM68360.2 - 0.018 15.8 0.0 0.043 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CAM68360.2 - 0.029 14.5 0.0 0.071 13.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 CAM68360.2 - 0.037 14.3 0.0 0.09 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 CAM68360.2 - 0.067 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 NTPase DUF572 PF04502.8 CAM68360.2 - 7.8 5.6 15.1 11 5.0 10.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Mnd1 PF03962.10 CAM68362.1 - 6.6e-29 100.9 0.0 1.4e-28 99.8 0.0 1.5 1 1 0 1 1 1 1 Mnd1 family GPP34 PF05719.6 CAM68362.1 - 0.55 10.2 9.7 0.11 12.5 0.9 2.2 1 1 0 2 2 2 0 Golgi phosphoprotein 3 (GPP34) Kelch_6 PF13964.1 CAM68363.1 - 8.2e-16 57.4 3.6 0.00018 21.4 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 CAM68363.1 - 9e-16 57.3 5.0 4e-07 29.7 0.0 4.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 CAM68363.1 - 1.3e-12 47.0 1.8 2.8e-05 23.5 0.0 3.7 3 1 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 CAM68363.1 - 6.4e-11 42.1 1.1 0.029 14.5 0.0 4.3 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_5 PF13854.1 CAM68363.1 - 1.5e-09 37.6 2.3 0.00051 19.9 0.0 3.5 4 0 0 4 4 4 2 Kelch motif F-box PF00646.28 CAM68363.1 - 7.2e-06 25.5 0.3 1.8e-05 24.2 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CAM68363.1 - 8.4e-06 25.4 0.5 1.8e-05 24.3 0.4 1.5 1 0 0 1 1 1 1 F-box-like Kelch_2 PF07646.10 CAM68363.1 - 0.00078 19.1 0.0 1.3 8.9 0.0 3.6 3 0 0 3 3 3 2 Kelch motif TctA PF01970.11 CAM68363.1 - 0.11 10.8 0.1 0.18 10.1 0.0 1.3 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family LRR_4 PF12799.2 CAM68364.1 - 7.5e-16 57.3 11.7 1.4e-07 30.9 0.5 3.5 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM68364.1 - 1.6e-07 30.9 9.3 7.7e-06 25.5 0.7 3.1 1 1 2 3 3 3 2 Leucine rich repeat LRR_9 PF14580.1 CAM68364.1 - 2.2e-07 30.5 0.9 9.4e-07 28.5 0.5 2.0 1 1 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.28 CAM68364.1 - 0.0002 20.9 5.7 0.75 10.0 0.2 4.8 3 2 0 3 3 3 2 Leucine Rich Repeat LRR_7 PF13504.1 CAM68364.1 - 0.0018 18.1 5.5 1.6 9.2 0.4 4.7 4 1 1 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 CAM68364.1 - 0.011 15.7 7.8 1.3 9.2 0.2 4.5 4 1 1 5 5 5 0 Leucine Rich repeat FNIP PF05725.7 CAM68364.1 - 0.027 14.4 0.3 0.07 13.0 0.2 1.7 1 0 0 1 1 1 0 FNIP Repeat LRR_3 PF07725.7 CAM68364.1 - 9.5 6.2 7.0 3.1 7.7 0.1 3.3 3 0 0 3 3 3 0 Leucine Rich Repeat SNF2_N PF00176.18 CAM68366.1 - 1.3e-38 132.5 0.0 3.9e-38 130.9 0.0 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CAM68366.1 - 4e-13 49.0 0.0 1.7e-12 47.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAM68366.1 - 0.0025 17.6 0.0 0.047 13.5 0.0 2.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AKAP7_NLS PF10469.4 CAM68367.1 - 1.9e-16 60.4 0.0 3.7e-16 59.4 0.0 1.5 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain TRAPPC10 PF12584.3 CAM68368.1 - 0.022 14.2 0.0 0.071 12.6 0.0 1.8 1 0 0 1 1 1 0 Trafficking protein particle complex subunit 10, TRAPPC10 DUF530 PF04409.7 CAM68368.1 - 2.1 6.3 0.0 3 5.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF530) DnaJ PF00226.26 CAM68369.1 - 2.9e-14 52.5 0.0 2e-13 49.8 0.0 2.2 2 0 0 2 2 2 1 DnaJ domain DUF2419 PF10343.4 CAM68369.1 - 0.08 12.1 0.2 0.12 11.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2419) DUF983 PF06170.7 CAM68370.1 - 0.81 9.8 0.1 0.81 9.8 0.0 3.8 4 1 1 5 5 5 0 Protein of unknown function (DUF983) HA2 PF04408.18 CAM68371.1 - 2e-16 59.8 0.0 5.4e-16 58.4 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CAM68371.1 - 3.5e-12 46.1 0.0 8.4e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CAM68371.1 - 4e-11 42.6 0.0 1.1e-10 41.2 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAM68371.1 - 6.5e-06 25.7 0.0 1.5e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CAM68371.1 - 0.00082 19.5 0.0 0.0026 17.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CAM68371.1 - 0.038 14.2 0.0 0.12 12.7 0.0 1.9 1 0 0 1 1 1 0 ABC transporter KaiC PF06745.8 CAM68371.1 - 0.1 11.6 0.1 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.1 CAM68371.1 - 0.35 11.1 0.2 0.85 9.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain FH2 PF02181.18 CAM68372.1 - 2.5e-53 181.2 0.0 3.3e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain PTEN_C2 PF10409.4 CAM68372.1 - 0.0027 17.4 0.0 0.011 15.4 0.0 1.9 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein EF-hand_6 PF13405.1 CAM68373.1 - 0.0091 15.8 0.0 1.4 9.0 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain Cnd1_N PF12922.2 CAM68373.1 - 1.1 8.8 3.6 0.33 10.5 0.1 1.8 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term IncA PF04156.9 CAM68375.1 - 2.3e-05 24.0 86.6 0.0045 16.5 5.1 5.4 4 1 1 5 5 5 4 IncA protein Reo_sigmaC PF04582.7 CAM68375.1 - 3.3 6.8 15.5 0.14 11.3 0.5 4.0 4 1 1 5 5 5 0 Reovirus sigma C capsid protein EF-hand_1 PF00036.27 CAM68376.1 - 0.059 12.6 0.0 15 5.2 0.0 2.6 2 0 0 2 2 2 0 EF hand RNA_pol PF00940.14 CAM68377.1 - 3.5e-128 427.5 0.0 4.9e-128 427.0 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase Lge1 PF11488.3 CAM68378.1 - 1.7 8.9 5.7 1 9.5 0.2 3.1 2 2 0 2 2 2 0 Transcriptional regulatory protein LGE1 Prominin PF05478.6 CAM68378.1 - 3.9 4.8 4.4 6.9 4.0 3.0 1.3 1 0 0 1 1 1 0 Prominin Adaptin_binding PF10199.4 CAM68379.1 - 0.00041 20.6 0.0 0.15 12.3 0.0 3.3 3 1 0 3 3 3 2 Alpha and gamma adaptin binding protein p34 SURF6 PF04935.7 CAM68380.1 - 1.4e-14 53.9 10.1 2.5e-14 53.1 7.0 1.5 1 0 0 1 1 1 1 Surfeit locus protein 6 Bax1-I PF01027.15 CAM68381.1 - 1.7e-37 129.0 19.4 1.7e-37 129.0 13.4 1.8 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 YL1 PF05764.8 CAM68382.1 - 3.5e-06 26.7 31.7 2e-05 24.3 21.9 1.9 1 1 0 1 1 1 1 YL1 nuclear protein HD_4 PF13328.1 CAM68382.1 - 0.05 13.3 4.2 0.11 12.1 2.9 1.6 1 0 0 1 1 1 0 HD domain RNA_pol_3_Rpc31 PF11705.3 CAM68382.1 - 7.9 6.3 24.0 1.6 8.6 11.0 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 SUI1 PF01253.17 CAM68383.1 - 3.1e-24 84.5 0.4 4.3e-24 84.1 0.3 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 Acylphosphatase PF00708.13 CAM68383.1 - 0.046 13.8 0.1 0.077 13.1 0.0 1.4 1 1 0 1 1 1 0 Acylphosphatase RIP PF00161.14 CAM68383.1 - 0.067 12.3 0.2 0.076 12.1 0.1 1.1 1 0 0 1 1 1 0 Ribosome inactivating protein RRM_6 PF14259.1 CAM68384.1 - 0.004 17.0 0.0 0.0084 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAM68384.1 - 0.0048 16.5 0.2 0.013 15.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM68384.1 - 0.022 14.5 0.0 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spuma_A9PTase PF03539.9 CAM68384.1 - 0.082 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) PHD PF00628.24 CAM68385.2 - 1.6e-05 24.4 10.6 1.6e-05 24.4 7.4 1.8 2 0 0 2 2 2 1 PHD-finger Acetyltransf_10 PF13673.1 CAM68385.2 - 0.058 13.5 0.3 2.1 8.4 0.2 2.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CAM68385.2 - 0.067 13.3 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CAM68385.2 - 0.075 13.0 1.8 0.48 10.4 0.2 2.8 2 1 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 CAM68385.2 - 0.12 12.2 0.6 1.3 8.8 0.4 2.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Amastin PF07344.6 CAM68387.1 - 3.1e-35 121.0 11.8 4.1e-35 120.7 8.2 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Peptidase_C7 PF01830.13 CAM68387.1 - 0.028 13.5 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase C7 family Amastin PF07344.6 CAM68388.1 - 1.5e-42 144.8 13.1 1.8e-42 144.5 9.1 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF202 PF02656.10 CAM68388.1 - 9 6.6 8.3 1.1e+02 3.1 5.8 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Amastin PF07344.6 CAM68389.1 - 1.9e-46 157.5 15.3 2.2e-46 157.2 10.6 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF1345 PF07077.6 CAM68389.1 - 3.4 7.1 9.0 0.17 11.3 1.9 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1345) Caveolin PF01146.12 CAM68389.1 - 7.2 6.1 14.1 4.4 6.8 5.6 2.3 2 0 0 2 2 2 0 Caveolin Amastin PF07344.6 CAM68390.1 - 8.4e-35 119.6 11.7 1.2e-34 119.1 8.1 1.2 1 0 0 1 1 1 1 Amastin surface glycoprotein Peptidase_C7 PF01830.13 CAM68390.1 - 0.054 12.6 0.0 0.081 12.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase C7 family WASH-7_mid PF14744.1 CAM68391.1 - 1.3e-139 464.8 0.1 2.1e-139 464.2 0.1 1.3 1 0 0 1 1 1 1 WASH complex subunit 7 WASH-7_C PF14746.1 CAM68391.1 - 4.1e-53 179.4 0.2 9e-53 178.3 0.1 1.6 1 0 0 1 1 1 1 WASH complex subunit 7, C-terminal WASH-7_N PF14745.1 CAM68391.1 - 2.5e-48 164.6 0.7 2e-23 82.4 0.0 3.2 2 2 0 2 2 2 2 WASH complex subunit 7, N-terminal DnaJ PF00226.26 CAM68392.1 - 5.1e-10 38.9 0.0 1.5e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain PAS PF00989.19 CAM68392.1 - 0.073 12.8 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 PAS fold BLUF PF04940.7 CAM68393.1 - 0.046 13.4 0.1 0.39 10.4 0.0 2.1 2 0 0 2 2 2 0 Sensors of blue-light using FAD Pro_isomerase PF00160.16 CAM68394.1 - 5.4e-25 88.4 0.0 7.1e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TRAPP PF04051.11 CAM68395.1 - 2.6e-06 27.0 0.0 2.8e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component GTP_EFTU PF00009.22 CAM68397.1 - 6.2e-25 87.7 0.6 5.2e-24 84.7 0.4 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CAM68397.1 - 6.3e-10 39.0 0.0 2.1e-09 37.3 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CAM68397.1 - 3e-06 27.7 0.0 9.4e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 CAM68397.1 - 4.3e-06 26.2 0.1 4.2e-05 23.0 0.0 2.4 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation IF-2 PF11987.3 CAM68397.1 - 0.00011 21.9 0.0 0.00031 20.5 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 Dynamin_N PF00350.18 CAM68397.1 - 0.0099 15.7 1.9 0.13 12.0 0.0 2.8 2 1 1 3 3 3 1 Dynamin family FeoB_N PF02421.13 CAM68397.1 - 0.023 13.9 0.1 0.069 12.4 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B cobW PF02492.14 CAM68397.1 - 0.094 12.1 3.6 0.56 9.6 0.3 3.3 3 1 1 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain IQ PF00612.22 CAM68398.1 - 4.1e-08 32.1 48.0 0.00063 19.1 0.4 7.3 5 1 2 7 7 7 5 IQ calmodulin-binding motif Hid1 PF12722.2 CAM68399.1 - 1.8e-30 105.4 0.9 7.4e-14 50.4 0.2 3.3 3 1 0 3 3 3 3 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 CAM68399.1 - 9.5e-23 80.1 0.0 2.5e-18 65.6 0.0 2.4 2 1 0 2 2 2 2 Dyggve-Melchior-Clausen syndrome protein Hist_deacetyl PF00850.14 CAM68400.1 - 4.4e-69 233.1 0.7 5.8e-69 232.7 0.5 1.1 1 0 0 1 1 1 1 Histone deacetylase domain EF-hand_7 PF13499.1 CAM68401.1 - 3.6e-21 75.0 3.5 5.3e-12 45.6 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CAM68401.1 - 1.8e-20 70.6 2.2 2.1e-05 23.4 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 CAM68401.1 - 1.2e-16 59.0 3.5 0.00036 20.1 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CAM68401.1 - 2.9e-16 57.9 1.9 8.2e-05 21.7 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 CAM68401.1 - 1.7e-11 43.5 2.8 1.3e-05 24.7 0.2 3.8 3 1 1 4 4 4 2 EF-hand domain pair zf-C3HC4_3 PF13920.1 CAM68401.1 - 1.9e-11 43.4 5.9 1.9e-11 43.4 4.1 2.0 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAM68401.1 - 1.2e-08 34.8 9.3 1.2e-08 34.8 6.4 2.1 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAM68401.1 - 4.1e-08 32.8 6.3 4.1e-08 32.8 4.3 2.3 2 1 0 2 2 1 1 zinc-RING finger domain SPARC_Ca_bdg PF10591.4 CAM68401.1 - 6.1e-08 32.6 0.0 4.3e-05 23.4 0.0 2.4 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region zf-C3HC4 PF00097.20 CAM68401.1 - 1.4e-07 31.0 4.4 1.4e-07 31.0 3.0 2.2 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CAM68401.1 - 1.4e-06 27.9 8.9 1.4e-06 27.9 6.1 2.3 1 1 1 2 2 2 1 Ring finger domain zf-RING_6 PF14835.1 CAM68401.1 - 1.4e-05 24.7 2.8 1.4e-05 24.7 1.9 1.7 2 0 0 2 2 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 CAM68401.1 - 0.00014 21.6 5.0 0.00014 21.6 3.4 2.7 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CAM68401.1 - 0.00026 20.6 6.7 0.00031 20.4 1.1 2.6 2 0 0 2 2 2 1 RING-type zinc-finger EF-hand_10 PF14788.1 CAM68401.1 - 0.0083 15.7 0.1 23 4.7 0.0 3.6 3 1 1 4 4 4 0 EF hand Prok-RING_4 PF14447.1 CAM68401.1 - 0.056 12.9 4.5 0.17 11.4 3.1 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 EF-hand_4 PF12763.2 CAM68401.1 - 0.32 10.7 1.3 9.2 6.0 0.1 2.8 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand zf-Nse PF11789.3 CAM68401.1 - 0.34 10.4 4.0 1.7 8.2 2.8 2.2 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF605 PF04652.11 CAM68401.1 - 0.85 8.9 11.0 1.2 8.4 7.6 1.2 1 0 0 1 1 1 0 Vta1 like Cript PF10235.4 CAM68401.1 - 3 8.2 7.2 0.93 9.8 0.6 2.6 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT EF-hand_1 PF00036.27 CAM68402.1 - 1.2e-21 74.3 2.0 1.7e-05 23.7 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 CAM68402.1 - 1.6e-21 76.1 3.5 2.9e-12 46.5 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CAM68402.1 - 2.8e-17 60.9 3.4 0.00028 20.5 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CAM68402.1 - 2.3e-16 58.2 2.2 6.7e-05 22.0 0.1 4.3 4 0 0 4 4 4 4 EF hand zf-C3HC4_3 PF13920.1 CAM68402.1 - 1.5e-11 43.7 5.9 1.5e-11 43.7 4.1 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) EF-hand_8 PF13833.1 CAM68402.1 - 2.5e-11 42.9 2.3 9.6e-05 21.9 0.1 4.1 3 1 1 4 4 4 2 EF-hand domain pair zf-C3HC4_2 PF13923.1 CAM68402.1 - 9.4e-09 35.1 9.3 9.4e-09 35.1 6.4 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) SPARC_Ca_bdg PF10591.4 CAM68402.1 - 2.5e-08 33.9 0.0 2.1e-05 24.4 0.0 2.4 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region zf-RING_5 PF14634.1 CAM68402.1 - 3.3e-08 33.1 6.3 3.3e-08 33.1 4.3 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CAM68402.1 - 1.2e-07 31.2 4.5 1.2e-07 31.2 3.1 2.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CAM68402.1 - 8.2e-07 28.7 10.3 1.1e-06 28.2 6.1 2.0 1 1 1 2 2 2 1 Ring finger domain zf-RING_6 PF14835.1 CAM68402.1 - 4.8e-06 26.2 2.8 1.1e-05 25.1 1.9 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 CAM68402.1 - 0.00012 21.9 5.0 0.00012 21.9 3.4 2.6 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CAM68402.1 - 0.0002 20.9 6.7 0.00025 20.7 1.1 2.5 2 0 0 2 2 2 1 RING-type zinc-finger EF-hand_10 PF14788.1 CAM68402.1 - 0.0036 16.9 0.2 17 5.1 0.0 3.7 3 1 1 4 4 4 0 EF hand zf-C2HC5 PF06221.8 CAM68402.1 - 0.01 15.5 1.3 0.01 15.5 0.9 1.9 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Prok-RING_4 PF14447.1 CAM68402.1 - 0.038 13.5 4.5 0.14 11.7 3.1 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 EF-hand_4 PF12763.2 CAM68402.1 - 0.3 10.8 1.4 7.1 6.4 0.1 2.5 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand zf-Nse PF11789.3 CAM68402.1 - 0.55 9.7 5.3 3 7.4 3.5 2.3 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Cript PF10235.4 CAM68402.1 - 7 7.0 7.3 0.73 10.2 0.6 2.2 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT GCOM2 PF15328.1 CAM68403.1 - 0.057 13.1 8.2 0.07 12.8 5.7 1.2 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 DUF4616 PF15394.1 CAM68403.1 - 0.1 11.6 5.0 0.12 11.3 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4616) Cluap1 PF10234.4 CAM68403.1 - 0.14 11.3 14.3 0.18 10.9 9.9 1.0 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF641 PF04859.7 CAM68403.1 - 0.56 9.9 19.6 0.35 10.6 4.5 3.0 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) DUF4200 PF13863.1 CAM68403.1 - 0.76 9.7 27.8 3.9 7.4 5.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) V_ATPase_I PF01496.14 CAM68403.1 - 2.6 5.8 7.7 3.2 5.5 5.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_TATA_bd PF12325.3 CAM68403.1 - 2.6 7.7 23.1 0.19 11.4 9.7 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF16 PF01519.11 CAM68403.1 - 5.5 7.2 8.5 25 5.1 5.3 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 DNA_mis_repair PF01119.14 CAM68405.1 - 6.2e-24 83.7 0.0 1.1e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain Kinesin PF00225.18 CAM68406.2 - 4.6e-58 196.5 0.0 1.8e-40 138.6 0.0 2.3 2 0 0 2 2 2 2 Kinesin motor domain DUF2450 PF10475.4 CAM68406.2 - 0.057 12.3 0.7 0.093 11.6 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) AAA_22 PF13401.1 CAM68406.2 - 0.25 11.5 0.0 1 9.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain P4Ha_N PF08336.6 CAM68406.2 - 0.3 10.9 2.6 0.61 9.9 1.8 1.4 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DASH_Dad3 PF08656.5 CAM68406.2 - 0.35 10.5 0.8 1.8 8.2 0.2 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad3 DivIC PF04977.10 CAM68406.2 - 0.88 9.1 4.0 2.1 7.9 2.7 1.6 1 0 0 1 1 1 0 Septum formation initiator DUF1515 PF07439.6 CAM68406.2 - 1.9 8.3 5.8 0.36 10.6 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Pkinase PF00069.20 CAM68409.1 - 2.4e-63 213.7 0.0 3.1e-63 213.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM68409.1 - 5.5e-41 140.3 0.0 8.2e-41 139.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CAM68409.1 - 0.00011 21.4 0.0 0.00023 20.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-ribbon_3 PF13248.1 CAM68409.1 - 0.0006 18.9 1.4 0.0011 18.0 0.9 1.4 1 0 0 1 1 1 1 zinc-ribbon domain APH PF01636.18 CAM68409.1 - 0.0038 16.9 0.0 0.14 11.9 0.1 2.9 1 1 2 3 3 3 1 Phosphotransferase enzyme family DZR PF12773.2 CAM68409.1 - 0.0059 16.3 0.7 0.012 15.3 0.5 1.4 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.1 CAM68409.1 - 0.0098 15.3 2.6 0.024 14.0 1.8 1.7 1 1 0 1 1 1 1 zinc-ribbon domain Kinase-like PF14531.1 CAM68409.1 - 0.038 12.9 0.0 0.06 12.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF2931 PF11153.3 CAM68409.1 - 0.058 12.7 0.0 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2931) NOB1_Zn_bind PF08772.6 CAM68409.1 - 0.059 13.1 0.6 0.11 12.2 0.4 1.4 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_5 PF13719.1 CAM68409.1 - 0.14 11.7 0.8 7.7 6.1 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-NADH-PPase PF09297.6 CAM68409.1 - 0.37 10.3 9.5 0.57 9.7 2.4 2.7 1 1 1 2 2 2 0 NADH pyrophosphatase zinc ribbon domain WD40 PF00400.27 CAM68410.1 - 0.0037 17.0 10.7 2.4 8.1 0.1 7.1 8 0 0 8 8 8 1 WD domain, G-beta repeat Viral_DNA_bp PF00747.12 CAM68410.1 - 1.2 6.2 0.0 1.7 5.7 0.0 1.1 1 0 0 1 1 1 0 ssDNA binding protein START PF01852.14 CAM68411.1 - 0.00013 21.4 0.0 0.98 8.6 0.0 3.3 3 0 0 3 3 3 2 START domain DUF2921 PF11145.3 CAM68411.1 - 0.0022 15.8 0.0 0.0031 15.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2921) Calpain_inhib PF00748.14 CAM68411.1 - 0.039 14.2 0.8 0.13 12.6 0.6 1.8 1 0 0 1 1 1 0 Calpain inhibitor WD40 PF00400.27 CAM68412.1 - 1.5e-15 56.4 5.0 1.2e-07 31.2 0.1 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat RNA_pol_3_Rpc31 PF11705.3 CAM68412.1 - 0.34 10.7 8.5 0.67 9.8 5.9 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Tom22 PF04281.8 CAM68412.1 - 2.5 7.6 6.5 5.5 6.5 4.5 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 FYDLN_acid PF09538.5 CAM68412.1 - 6.6 7.3 12.8 15 6.2 8.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) TCTP PF00838.12 CAM68413.1 - 4.2e-38 130.9 1.1 4.8e-38 130.7 0.8 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein AAA_15 PF13175.1 CAM68413.1 - 0.031 13.3 0.6 0.034 13.1 0.4 1.1 1 0 0 1 1 1 0 AAA ATPase domain Ribosomal_S20p PF01649.13 CAM68413.1 - 0.033 14.5 0.5 0.052 13.9 0.4 1.3 1 0 0 1 1 1 0 Ribosomal protein S20 RICH PF05062.7 CAM68413.1 - 0.042 13.9 0.4 0.073 13.2 0.3 1.4 1 0 0 1 1 1 0 RICH domain AlaDh_PNT_C PF01262.16 CAM68413.1 - 0.1 12.1 0.3 0.16 11.5 0.2 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TCTP PF00838.12 CAM68414.1 - 4.2e-38 130.9 1.1 4.8e-38 130.7 0.8 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein AAA_15 PF13175.1 CAM68414.1 - 0.031 13.3 0.6 0.034 13.1 0.4 1.1 1 0 0 1 1 1 0 AAA ATPase domain Ribosomal_S20p PF01649.13 CAM68414.1 - 0.033 14.5 0.5 0.052 13.9 0.4 1.3 1 0 0 1 1 1 0 Ribosomal protein S20 RICH PF05062.7 CAM68414.1 - 0.042 13.9 0.4 0.073 13.2 0.3 1.4 1 0 0 1 1 1 0 RICH domain AlaDh_PNT_C PF01262.16 CAM68414.1 - 0.1 12.1 0.3 0.16 11.5 0.2 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ERCC4 PF02732.10 CAM68415.1 - 1.3e-12 47.7 0.0 2.9e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 ERCC4 domain SAP PF02037.22 CAM68415.1 - 6.3e-06 25.5 0.2 1.8e-05 24.1 0.2 1.8 1 0 0 1 1 1 1 SAP domain Helicase_C PF00271.26 CAM68416.1 - 1.6e-15 56.6 0.0 2.1e-14 53.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAM68416.1 - 9.2e-15 54.5 0.0 6.2e-14 51.8 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase HRDC PF00570.18 CAM68416.1 - 0.0002 21.0 0.0 0.00043 19.9 0.0 1.6 1 0 0 1 1 1 1 HRDC domain Choline_kin_N PF04428.9 CAM68416.1 - 0.12 11.9 0.0 0.35 10.3 0.0 1.8 1 0 0 1 1 1 0 Choline kinase N terminus Fmp27 PF10344.4 CAM68418.1 - 0.16 9.6 0.2 0.22 9.1 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 SPRY PF00622.23 CAM68419.1 - 0.0088 16.1 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 1 SPRY domain Cyclin PF08613.6 CAM68420.1 - 3.5e-18 66.4 0.1 7.4e-18 65.3 0.1 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CAM68420.1 - 1.3e-08 34.4 0.1 2.6e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 CAM68421.1 - 8.6e-20 71.6 0.0 1.5e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CAM68421.1 - 9e-07 28.5 0.0 1.4e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain WD40 PF00400.27 CAM68422.1 - 1.7e-38 129.1 24.7 5.4e-09 35.6 0.1 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat PFU PF09070.6 CAM68422.1 - 1.8e-32 111.7 0.2 2.7e-32 111.1 0.2 1.3 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PPTA PF01239.17 CAM68423.1 - 0.0015 17.7 15.0 0.033 13.5 1.9 3.4 3 0 0 3 3 3 2 Protein prenyltransferase alpha subunit repeat DnaJ PF00226.26 CAM68424.1 - 0.0021 17.7 0.0 0.0037 16.9 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain HAP1_N PF04849.8 CAM68425.1 - 0.14 11.0 21.3 0.011 14.6 6.6 2.4 2 0 0 2 2 2 0 HAP1 N-terminal conserved region DUF972 PF06156.8 CAM68425.1 - 0.39 11.0 12.6 1.2 9.5 0.4 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF972) ADIP PF11559.3 CAM68425.1 - 0.86 9.4 26.9 0.45 10.3 5.8 3.2 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Ins134_P3_kin PF05770.6 CAM68426.1 - 6.8e-07 28.5 0.1 0.01 14.8 0.0 4.1 4 0 0 4 4 4 4 Inositol 1, 3, 4-trisphosphate 5/6-kinase Reo_sigmaC PF04582.7 CAM68429.2 - 0.41 9.7 13.9 0.018 14.2 3.7 2.8 2 1 0 3 3 3 0 Reovirus sigma C capsid protein HALZ PF02183.13 CAM68429.2 - 3.2 7.5 11.7 1.2 8.9 0.7 4.3 4 0 0 4 4 4 0 Homeobox associated leucine zipper STOP PF05217.7 CAM68431.1 - 2.2e-10 40.6 16.6 2.1e-08 34.1 11.5 3.6 1 1 0 1 1 1 1 STOP protein TruB_C PF09142.6 CAM68431.1 - 0.1 12.2 0.0 0.34 10.5 0.0 1.9 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal PCIF1_WW PF12237.3 CAM68433.1 - 7.2e-08 31.9 0.0 2.1e-07 30.4 0.0 1.8 1 1 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain Surf_Ag_VNR PF07244.10 CAM68433.1 - 0.12 12.7 0.0 0.38 11.2 0.0 1.8 1 0 0 1 1 1 0 Surface antigen variable number repeat PI3_PI4_kinase PF00454.22 CAM68434.2 - 2.1e-42 145.2 0.0 4.9e-40 137.4 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 CAM68434.2 - 2.7e-22 78.8 0.0 5.4e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.19 CAM68434.2 - 3.7e-05 23.5 0.0 8.2e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.1 CAM68434.2 - 0.35 9.8 0.0 0.53 9.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) TFCD_C PF12612.3 CAM68435.1 - 1.2e-21 76.9 0.0 4.2e-21 75.2 0.0 2.0 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.1 CAM68435.1 - 1.8e-09 37.7 15.9 0.033 14.4 0.3 7.2 6 0 0 6 6 6 5 HEAT repeats HEAT PF02985.17 CAM68435.1 - 0.0002 21.1 33.3 0.3 11.2 0.0 11.3 12 1 1 13 13 13 3 HEAT repeat Cnd1 PF12717.2 CAM68435.1 - 0.0023 17.8 1.0 2.6 7.8 0.0 4.6 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 adh_short PF00106.20 CAM68436.1 - 1.6e-25 89.9 5.7 2e-25 89.6 4.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CAM68436.1 - 6.7e-14 52.2 0.0 3.9e-13 49.7 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CAM68436.1 - 9.3e-12 44.9 3.9 2.3e-11 43.7 2.7 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 CAM68436.1 - 2.7e-06 27.0 0.2 3.9e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CAM68436.1 - 0.00011 22.2 0.8 0.00018 21.5 0.6 1.3 1 0 0 1 1 1 1 NADH(P)-binding DAO PF01266.19 CAM68436.1 - 0.0024 16.8 0.1 0.003 16.5 0.1 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase 3Beta_HSD PF01073.14 CAM68436.1 - 0.011 14.4 0.3 0.019 13.6 0.2 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CAM68436.1 - 0.026 13.4 0.5 0.22 10.4 0.4 2.0 1 1 0 1 1 1 0 Male sterility protein 3HCDH_N PF02737.13 CAM68436.1 - 0.029 14.0 0.8 0.052 13.2 0.5 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 CAM68436.1 - 0.063 13.0 0.6 0.17 11.6 0.4 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2-Hacid_dh_C PF02826.14 CAM68436.1 - 0.078 12.1 0.4 0.15 11.1 0.1 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NmrA PF05368.8 CAM68436.1 - 0.15 11.2 0.8 0.27 10.4 0.5 1.4 1 0 0 1 1 1 0 NmrA-like family BolA PF01722.13 CAM68437.1 - 1e-16 60.6 0.0 1.3e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein KOW PF00467.24 CAM68439.1 - 1.2e-06 28.0 0.7 3.5e-06 26.4 0.5 1.9 1 1 0 1 1 1 1 KOW motif Transketolase_N PF00456.16 CAM68440.1 - 6.8e-135 449.1 0.1 9e-135 448.7 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 CAM68440.1 - 1.9e-43 148.0 0.0 3.3e-43 147.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CAM68440.1 - 1.6e-10 41.0 0.1 3.4e-10 39.9 0.1 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.16 CAM68440.1 - 0.0001 21.9 0.2 0.00054 19.5 0.1 2.3 1 1 1 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 CAM68440.1 - 0.00068 18.6 0.0 0.009 14.9 0.0 2.1 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 CAM68440.1 - 0.073 11.7 0.0 0.12 11.0 0.0 1.4 1 0 0 1 1 1 0 Dehydrogenase E1 component Terpene_synth PF01397.16 CAM68440.1 - 0.21 10.9 0.1 0.49 9.7 0.0 1.5 2 0 0 2 2 2 0 Terpene synthase, N-terminal domain Ribosomal_S8e PF01201.17 CAM68441.1 - 2.3e-44 150.7 2.3 2.7e-44 150.5 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e HTH_psq PF05225.11 CAM68441.1 - 0.82 9.2 4.1 0.39 10.3 0.8 2.0 2 0 0 2 2 2 0 helix-turn-helix, Psq domain Ribosomal_S8e PF01201.17 CAM68442.1 - 2.3e-44 150.7 2.3 2.7e-44 150.5 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e HTH_psq PF05225.11 CAM68442.1 - 0.82 9.2 4.1 0.39 10.3 0.8 2.0 2 0 0 2 2 2 0 helix-turn-helix, Psq domain Kelch_3 PF13415.1 CAM68443.1 - 2.5e-48 161.2 9.1 2e-12 46.8 0.0 7.3 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.1 CAM68443.1 - 7.3e-42 140.9 19.3 9.4e-08 31.7 0.0 7.0 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.20 CAM68443.1 - 2.1e-31 107.1 20.2 1.2e-06 27.9 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.1 CAM68443.1 - 5.8e-31 105.9 14.4 2.7e-06 27.1 0.5 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 CAM68443.1 - 1.4e-30 104.1 11.4 6e-08 32.5 0.0 6.2 4 1 2 6 6 6 4 Kelch motif Kelch_2 PF07646.10 CAM68443.1 - 4.6e-26 89.5 16.1 1.5e-06 27.6 0.3 6.6 6 1 0 6 6 6 6 Kelch motif TPR_16 PF13432.1 CAM68444.1 - 0.021 15.5 2.3 0.021 15.5 1.6 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 CAM68444.1 - 0.021 15.1 0.4 0.059 13.7 0.3 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat HMG_CoA_synt_N PF01154.12 CAM68445.1 - 3.5e-12 46.2 0.1 7.8e-12 45.0 0.1 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.5 CAM68445.1 - 1.4e-06 28.0 0.1 0.00063 19.3 0.0 2.3 2 0 0 2 2 2 2 Hydroxymethylglutaryl-coenzyme A synthase C terminal ACP_syn_III PF08545.5 CAM68445.1 - 7.6e-05 22.2 0.2 0.00022 20.8 0.1 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III UQ_con PF00179.21 CAM68447.1 - 4.2e-44 149.3 0.1 4.6e-44 149.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CAM68447.1 - 0.00024 20.9 0.1 0.00042 20.1 0.1 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 CAM68447.1 - 0.00073 19.2 0.3 0.0012 18.5 0.2 1.4 1 1 0 1 1 1 1 UEV domain Prok-E2_B PF14461.1 CAM68447.1 - 0.036 13.8 0.1 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UQ_con PF00179.21 CAM68448.1 - 5.1e-07 29.2 0.0 7.8e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CAM68448.1 - 0.0056 16.5 0.0 0.0077 16.1 0.0 1.3 1 0 0 1 1 1 1 RWD domain GDPD PF03009.12 CAM68450.1 - 3.8e-22 79.0 0.0 5.1e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF2450 PF10475.4 CAM68451.1 - 2e-16 59.7 0.7 3.9e-16 58.7 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) DUF2451 PF10474.4 CAM68451.1 - 9.1e-07 28.8 0.5 1.7e-06 27.9 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Sec8_exocyst PF04048.9 CAM68451.1 - 0.011 15.4 0.7 0.024 14.2 0.5 1.5 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain FlxA PF14282.1 CAM68452.2 - 0.0026 17.6 6.4 0.0026 17.6 4.4 14.7 5 4 8 15 15 15 4 FlxA-like protein Peptidase_M56 PF05569.6 CAM68453.1 - 0.087 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 RskA PF10099.4 CAM68453.1 - 0.12 12.1 4.5 0.18 11.5 3.1 1.6 1 1 0 1 1 1 0 Anti-sigma-K factor rskA PPR_3 PF13812.1 CAM68454.1 - 1.2e-07 31.3 1.1 0.0001 22.3 0.0 4.1 3 1 0 3 3 3 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 CAM68454.1 - 2.4e-07 30.6 0.1 0.012 15.5 0.0 3.5 2 1 2 4 4 4 3 PPR repeat family PPR PF01535.15 CAM68454.1 - 0.0092 15.9 0.1 10 6.3 0.0 3.7 4 0 0 4 4 4 1 PPR repeat Ribosomal_L11_N PF03946.9 CAM68455.1 - 7.6e-15 54.1 0.2 1.3e-14 53.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 CAM68455.1 - 2.4e-11 43.6 0.5 4.5e-11 42.7 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain AAA_5 PF07728.9 CAM68456.1 - 0.025 14.2 0.0 0.081 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 CAM68456.1 - 0.083 13.0 0.0 0.22 11.7 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CAM68456.1 - 0.15 12.0 0.0 0.39 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain DUF1469 PF07332.6 CAM68457.1 - 3.1 7.5 6.9 1.6 8.4 2.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Cob_adeno_trans PF01923.13 CAM68458.1 - 1.1e-46 158.6 0.4 1.7e-46 158.0 0.3 1.3 1 0 0 1 1 1 1 Cobalamin adenosyltransferase FA_desaturase PF00487.19 CAM68459.1 - 9.1e-14 51.5 22.4 2.1e-13 50.3 13.6 2.0 1 1 1 2 2 2 2 Fatty acid desaturase Cyt-b5 PF00173.23 CAM68459.1 - 2e-09 37.1 0.2 6.5e-06 25.8 0.0 3.0 2 1 1 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain WD40 PF00400.27 CAM68460.1 - 5.5e-78 254.3 28.7 6.1e-11 41.7 0.0 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat NLE PF08154.7 CAM68460.1 - 3.2e-16 59.0 0.0 5.3e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.6 CAM68460.1 - 4.4e-07 29.7 0.1 0.024 14.3 0.0 2.8 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 CAM68460.1 - 0.00021 20.8 2.3 2.9 7.6 0.1 4.3 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 CAM68460.1 - 0.0006 19.0 0.2 0.56 9.2 0.0 3.5 2 1 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal DUF1227 PF06777.6 CAM68462.1 - 5.9e-45 152.5 0.1 1.3e-44 151.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) Helicase_C_2 PF13307.1 CAM68462.1 - 5.3e-40 137.0 0.0 1.1e-39 136.0 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 CAM68462.1 - 1.3e-37 128.9 0.0 2.6e-37 127.8 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.24 CAM68462.1 - 0.00024 20.6 0.8 0.051 13.0 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 CAM68462.1 - 0.0033 17.2 0.7 0.031 14.0 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 CAM68462.1 - 0.018 14.7 0.7 1 9.1 0.0 2.6 2 0 0 2 2 2 0 Flavivirus DEAD domain Glyco_transf_21 PF13506.1 CAM68462.1 - 0.031 13.5 0.1 0.31 10.3 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 21 AAA_19 PF13245.1 CAM68462.1 - 0.044 13.5 0.1 0.19 11.5 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain SNF2_N PF00176.18 CAM68462.1 - 0.065 12.0 0.2 0.43 9.3 0.1 1.9 1 1 0 1 1 1 0 SNF2 family N-terminal domain Cullin PF00888.17 CAM68463.1 - 7.5e-68 229.4 0.0 9.8e-68 229.1 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CAM68463.1 - 8.3e-26 89.6 0.2 2.6e-25 88.0 0.1 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain Sugarporin_N PF11471.3 CAM68464.1 - 0.02 14.5 1.1 1.1 8.9 0.0 2.6 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Succ_CoA_lig PF13607.1 CAM68464.1 - 0.039 13.5 0.2 0.44 10.1 0.0 2.1 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain FlgN PF05130.7 CAM68464.1 - 0.082 13.1 0.5 7.3 6.8 0.0 2.2 2 0 0 2 2 2 0 FlgN protein DUF2051 PF09738.4 CAM68465.1 - 0.0001 21.7 13.5 0.0029 16.9 2.1 2.0 1 1 1 2 2 2 2 Double stranded RNA binding protein (DUF2051) RNase_H PF00075.19 CAM68465.1 - 0.0088 16.3 0.2 0.011 16.0 0.1 1.3 1 0 0 1 1 1 1 RNase H Myb_CC_LHEQLE PF14379.1 CAM68465.1 - 0.026 14.1 0.7 0.026 14.1 0.5 2.2 2 1 0 2 2 2 0 MYB-CC type transfactor, LHEQLE motif FlxA PF14282.1 CAM68465.1 - 0.076 12.9 10.6 0.31 11.0 0.6 2.2 2 0 0 2 2 2 0 FlxA-like protein Mod_r PF07200.8 CAM68465.1 - 0.16 11.8 12.5 1.5 8.7 2.8 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Baculo_PEP_C PF04513.7 CAM68465.1 - 0.19 11.5 1.2 0.33 10.7 0.4 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.1 CAM68465.1 - 0.25 11.6 14.3 6.3 7.1 0.5 3.7 1 1 2 3 3 3 0 Snapin/Pallidin Fib_alpha PF08702.5 CAM68465.1 - 0.38 10.8 5.6 0.29 11.2 1.7 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ADIP PF11559.3 CAM68465.1 - 0.43 10.4 13.9 0.56 10.1 7.7 1.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 CAM68465.1 - 0.45 10.0 17.4 0.028 13.9 5.7 2.1 1 1 1 2 2 2 0 IncA protein Mnd1 PF03962.10 CAM68465.1 - 0.47 10.0 11.2 0.62 9.6 7.2 1.6 1 1 0 1 1 1 0 Mnd1 family Tup_N PF08581.5 CAM68465.1 - 1.2 9.3 10.7 0.34 11.1 1.0 3.0 2 1 1 3 3 3 0 Tup N-terminal RIB43A PF05914.7 CAM68465.1 - 1.2 7.6 12.8 0.44 9.1 4.2 2.0 1 1 1 2 2 2 0 RIB43A DivIC PF04977.10 CAM68465.1 - 2.8 7.4 18.7 0.64 9.5 1.7 3.7 2 2 2 4 4 4 0 Septum formation initiator DUF1043 PF06295.7 CAM68465.1 - 3.1 7.4 7.0 16 5.1 1.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) TMPIT PF07851.8 CAM68465.1 - 3.9 6.4 8.4 5.5 5.9 2.0 2.0 1 1 1 2 2 2 0 TMPIT-like protein DUF4200 PF13863.1 CAM68465.1 - 9.7 6.1 19.9 3.7 7.5 0.3 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) Pkinase PF00069.20 CAM68466.1 - 3.7e-58 196.6 0.0 4.4e-58 196.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM68466.1 - 2e-39 135.2 0.0 2.6e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM68466.1 - 8.5e-05 21.6 0.0 0.00028 19.9 0.0 1.7 1 1 1 2 2 2 1 Kinase-like GAGA_bind PF06217.7 CAM68467.1 - 0.38 10.6 8.9 0.52 10.2 6.1 1.4 1 1 0 1 1 1 0 GAGA binding protein-like family SpoU_methylase PF00588.14 CAM68468.1 - 1.5e-13 50.8 0.0 2.9e-07 30.4 0.0 2.5 2 1 0 2 2 2 2 SpoU rRNA Methylase family Glycos_transf_2 PF00535.21 CAM68469.1 - 1e-08 35.0 0.2 2.5e-08 33.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.4 CAM68469.1 - 0.05 12.6 0.3 3.5 6.6 0.1 2.3 2 0 0 2 2 2 0 Glycosyltransferase like family 2 Acetyltransf_1 PF00583.19 CAM68470.1 - 1.1e-09 38.1 0.2 2.7e-09 36.9 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CAM68470.1 - 7.9e-08 31.9 0.0 1.3e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 CAM68470.1 - 0.0025 17.9 0.0 0.0051 16.9 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CAM68470.1 - 0.0069 16.5 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2431 PF10354.4 CAM68471.1 - 2.1e-21 76.5 0.0 1.2e-16 61.1 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF2431) zf-C2H2_jaz PF12171.3 CAM68471.1 - 3.7e-05 23.7 2.5 0.11 12.7 0.0 3.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 CAM68471.1 - 0.0003 20.8 22.0 0.07 13.4 0.6 4.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 CAM68471.1 - 0.00032 20.8 23.7 0.049 13.9 0.1 4.4 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-met PF12874.2 CAM68471.1 - 0.021 15.0 0.1 0.021 15.0 0.0 4.0 3 2 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CAM68471.1 - 0.14 12.0 12.0 0.36 10.8 0.0 3.5 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 CAM68471.1 - 9.1 6.4 7.5 18 5.4 1.0 3.1 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF972 PF06156.8 CAM68472.1 - 0.042 14.2 0.5 0.042 14.2 0.3 4.2 5 1 1 6 6 6 0 Protein of unknown function (DUF972) TSC22 PF01166.13 CAM68472.1 - 0.63 10.0 3.5 2.8 7.9 0.1 3.4 2 1 1 3 3 3 0 TSC-22/dip/bun family CEP44 PF15007.1 CAM68473.1 - 0.00038 20.1 0.0 0.00048 19.8 0.0 1.1 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 Got1 PF04178.7 CAM68474.1 - 3.3e-26 91.7 14.5 4.4e-26 91.2 10.1 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family AzlD PF05437.7 CAM68474.1 - 0.034 14.0 6.4 0.19 11.7 4.8 1.8 1 1 1 2 2 2 0 Branched-chain amino acid transport protein (AzlD) DUF3270 PF11674.3 CAM68474.1 - 3.3 7.7 8.1 0.36 10.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) RRM_1 PF00076.17 CAM68476.1 - 2.7e-65 215.9 0.5 4.3e-19 67.8 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM68476.1 - 1.7e-48 162.4 0.4 9.5e-16 57.5 0.0 4.7 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM68476.1 - 3.9e-33 113.0 0.5 6.6e-11 41.9 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 CAM68476.1 - 4.2e-19 67.9 0.2 8.3e-19 67.0 0.2 1.5 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.6 CAM68476.1 - 0.021 14.6 3.3 10 6.0 0.4 4.3 4 1 1 5 5 5 0 RNA binding motif SNARE PF05739.14 CAM68477.1 - 7.2e-06 25.5 0.1 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 SNARE domain Ketoacyl-synt_C PF02801.17 CAM68477.1 - 0.11 12.3 0.5 0.61 9.9 0.4 2.1 1 1 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain DUF812 PF05667.6 CAM68477.1 - 0.16 10.4 0.7 0.19 10.1 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) RPAP1_N PF08621.5 CAM68477.1 - 1.1 8.8 6.0 6.2 6.5 4.2 1.9 1 1 0 1 1 1 0 RPAP1-like, N-terminal RAMP4 PF06624.7 CAM68478.1 - 0.00017 21.0 0.0 0.0002 20.7 0.0 1.1 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF364 PF04016.7 CAM68478.1 - 0.055 12.7 0.0 0.065 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF364) OPT PF03169.10 CAM68478.1 - 0.056 11.8 0.1 0.061 11.7 0.1 1.0 1 0 0 1 1 1 0 OPT oligopeptide transporter protein Kei1 PF08552.6 CAM68478.1 - 0.11 12.1 0.1 0.13 11.9 0.0 1.0 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 ETF PF01012.16 CAM68480.1 - 1.2e-37 129.1 1.5 1.6e-37 128.7 1.0 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain DUF4468 PF14730.1 CAM68480.1 - 0.12 12.0 0.1 1.6 8.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4468) with TBP-like fold Y_Y_Y PF07495.8 CAM68480.1 - 0.19 11.5 0.3 1.4 8.7 0.1 2.1 2 0 0 2 2 2 0 Y_Y_Y domain GTP_EFTU PF00009.22 CAM68481.1 - 9.5e-49 165.3 0.2 1.5e-48 164.7 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 CAM68481.1 - 6.5e-13 48.3 0.0 1.6e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus Septin PF00735.13 CAM68481.1 - 1.1e-05 24.5 0.1 1.9e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 CAM68481.1 - 0.0001 22.2 0.1 0.00021 21.2 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CAM68481.1 - 0.0017 18.8 0.0 0.0038 17.7 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU_D2 PF03144.20 CAM68481.1 - 0.0022 18.0 0.0 0.0069 16.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 CAM68481.1 - 0.013 15.3 0.5 0.054 13.3 0.0 2.3 2 0 0 2 2 2 0 Elongation Factor G, domain II RNA_pol_Rpb6 PF01192.17 CAM68482.1 - 1.1e-09 37.9 0.0 1.9e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb6 DUF724 PF05266.9 CAM68484.1 - 0.008 15.8 4.4 0.06 12.9 1.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF724) TPR_MLP1_2 PF07926.7 CAM68484.1 - 0.062 13.0 8.3 0.032 13.9 3.0 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Trans_reg_C PF00486.23 CAM68484.1 - 0.15 12.0 0.7 0.45 10.4 0.1 2.1 2 1 0 2 2 2 0 Transcriptional regulatory protein, C terminal DUF4570 PF15134.1 CAM68484.1 - 0.17 11.7 0.2 0.17 11.7 0.1 2.8 2 2 1 3 3 3 0 Domain of unknown function (DUF4570) DUF1192 PF06698.6 CAM68484.1 - 0.25 11.1 0.2 0.25 11.1 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) CPSF100_C PF13299.1 CAM68485.1 - 4.7e-22 78.9 0.5 8e-22 78.1 0.0 1.7 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 CAM68485.1 - 1.3e-09 38.0 0.0 3.7e-09 36.5 0.0 1.8 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 CAM68485.1 - 0.00015 21.4 0.6 0.00069 19.3 0.1 2.1 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Peptidase_C12 PF01088.16 CAM68487.1 - 1.8e-58 197.2 0.0 2.1e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Clathrin PF00637.15 CAM68488.1 - 3.2e-07 30.0 7.8 9.5e-05 22.0 0.2 4.6 5 0 0 5 5 5 2 Region in Clathrin and VPS TPR_7 PF13176.1 CAM68488.1 - 0.023 14.4 11.1 0.49 10.3 0.3 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.1 CAM68488.1 - 0.15 12.3 0.1 0.15 12.3 0.1 6.1 5 2 1 6 6 6 0 Tetratricopeptide repeat DZR PF12773.2 CAM68488.1 - 0.21 11.4 4.3 0.81 9.5 2.9 2.0 1 1 0 1 1 1 0 Double zinc ribbon Mito_carr PF00153.22 CAM68489.1 - 2.8e-62 206.4 0.6 1.3e-20 72.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DSPc PF00782.15 CAM68491.1 - 8.3e-17 61.0 0.1 1.4e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 CAM68491.1 - 0.00023 21.2 0.0 0.00045 20.2 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.7 CAM68491.1 - 0.00026 20.4 0.0 0.00041 19.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.1 CAM68491.1 - 0.00037 20.7 0.1 0.00071 19.8 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 CAM68491.1 - 0.00061 19.2 0.2 0.00084 18.7 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF442 PF04273.8 CAM68491.1 - 0.024 14.5 0.1 0.047 13.5 0.1 1.5 1 0 0 1 1 1 0 Putative phosphatase (DUF442) Bud13 PF09736.4 CAM68492.1 - 3.9e-06 27.2 0.0 7.8e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA-splicing factor of RES complex TMF_DNA_bd PF12329.3 CAM68493.1 - 3.6 7.4 11.6 1.9 8.3 0.8 2.8 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Dynein_light PF01221.13 CAM68494.1 - 2.7e-37 126.6 0.1 2.9e-37 126.5 0.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 DUF972 PF06156.8 CAM68495.1 - 0.0093 16.3 2.3 0.0093 16.3 1.6 7.5 5 2 3 8 8 8 3 Protein of unknown function (DUF972) CALCOCO1 PF07888.6 CAM68496.1 - 0.44 8.7 19.4 0.022 13.0 7.2 2.1 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like V_ATPase_I PF01496.14 CAM68496.1 - 0.96 7.2 3.0 1.6 6.4 2.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Macoilin PF09726.4 CAM68496.1 - 1.5 7.0 18.5 1.3 7.2 6.1 2.8 3 0 0 3 3 3 0 Transmembrane protein CENP-F_leu_zip PF10473.4 CAM68496.1 - 1.8 8.4 26.0 0.069 13.0 10.6 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RRM_1 PF00076.17 CAM68497.1 - 2.9e-05 23.5 0.9 0.0017 17.9 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM68497.1 - 0.0095 15.8 0.0 0.058 13.3 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ATP_bind_4 PF01902.12 CAM68498.1 - 3.4e-29 101.7 0.0 1.7e-23 83.1 0.0 2.9 2 1 0 2 2 2 2 ATP-binding region FTR PF01913.13 CAM68499.1 - 0.045 13.4 0.2 0.047 13.4 0.2 1.1 1 0 0 1 1 1 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase TMEM171 PF15471.1 CAM68500.1 - 0.059 12.1 2.1 0.13 11.0 1.5 1.6 1 0 0 1 1 1 0 Transmembrane protein family 171 B9-C2 PF07162.6 CAM68501.1 - 1.5e-48 164.7 0.1 1.7e-48 164.5 0.1 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein SPRY PF00622.23 CAM68502.1 - 0.0013 18.8 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 SPRY domain DUF3570 PF12094.3 CAM68502.1 - 0.055 12.2 0.0 0.084 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3570) DUF1308 PF07000.6 CAM68504.1 - 2.5e-139 463.9 0.1 3.2e-139 463.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) XG_FTase PF03254.8 CAM68504.1 - 0.075 11.5 0.1 0.12 10.8 0.1 1.3 1 0 0 1 1 1 0 Xyloglucan fucosyltransferase DUF3847 PF12958.2 CAM68505.1 - 0.23 11.2 2.1 0.17 11.6 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) Fcf2 PF08698.6 CAM68506.1 - 2.3e-21 75.6 1.3 2.3e-21 75.6 0.9 1.8 1 1 1 2 2 2 1 Fcf2 pre-rRNA processing Chal_sti_synt_N PF00195.14 CAM68506.1 - 0.083 12.1 0.4 0.11 11.6 0.3 1.2 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain SUI1 PF01253.17 CAM68510.2 - 3.6e-19 68.3 0.0 6.3e-19 67.5 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 Noelin-1 PF12308.3 CAM68511.1 - 0.31 10.8 18.5 0.26 11.0 0.1 5.8 5 1 1 6 6 6 0 Neurogenesis glycoprotein Baculo_PEP_C PF04513.7 CAM68511.1 - 1.5 8.6 41.6 0.19 11.5 7.4 6.8 3 1 2 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus WD40 PF00400.27 CAM68512.1 - 9.2e-50 164.8 17.1 1.7e-09 37.1 0.0 9.1 9 0 0 9 9 9 6 WD domain, G-beta repeat Utp13 PF08625.6 CAM68512.1 - 4.3e-39 133.3 0.5 6.9e-39 132.7 0.4 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Utp12 PF04003.7 CAM68512.1 - 0.00015 21.6 0.3 0.00055 19.8 0.1 1.9 2 0 0 2 2 2 1 Dip2/Utp12 Family Nup160 PF11715.3 CAM68512.1 - 0.0086 14.2 7.2 0.63 8.1 0.2 4.0 3 1 0 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CAM68512.1 - 0.24 10.1 1.7 1.8 7.2 0.1 3.1 2 1 0 2 2 2 0 Nup133 N terminal like TFIIB PF00382.14 CAM68513.1 - 2e-23 81.9 0.0 1.6e-11 43.8 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 CAM68513.1 - 0.012 14.8 0.0 0.029 13.7 0.0 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding MMR_HSR1 PF01926.18 CAM68514.1 - 6.3e-13 48.6 0.0 1.1e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CAM68514.1 - 1.4e-07 30.9 0.0 7.6e-06 25.2 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 CAM68514.1 - 1.4e-05 24.3 0.0 3.4e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CAM68514.1 - 0.0016 18.2 0.3 0.29 10.9 0.0 2.4 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.11 CAM68514.1 - 0.0024 17.0 0.0 0.0038 16.3 0.0 1.3 1 0 0 1 1 1 1 AIG1 family SRPRB PF09439.5 CAM68514.1 - 0.015 14.5 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF2149 PF09919.4 CAM68515.1 - 0.085 12.9 0.1 0.36 10.9 0.1 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2149) Kringle PF00051.13 CAM68516.1 - 1e-07 31.9 0.0 2.2e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Kringle domain CHB_HEX_C PF03174.8 CAM68516.1 - 0.022 14.6 6.0 0.026 14.3 0.0 3.9 4 0 0 4 4 4 0 Chitobiase/beta-hexosaminidase C-terminal domain CHB_HEX_C_1 PF13290.1 CAM68516.1 - 0.073 12.8 4.8 0.1 12.3 0.1 3.5 3 0 0 3 3 3 0 Chitobiase/beta-hexosaminidase C-terminal domain RRM_1 PF00076.17 CAM68519.1 - 9.7e-22 76.3 0.0 1.3e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM68519.1 - 1.1e-15 57.2 0.0 2e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM68519.1 - 2.8e-13 49.4 0.0 4.5e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Coatomer_b_Cpla PF14806.1 CAM68520.1 - 0.2 11.3 0.0 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform RRM_1 PF00076.17 CAM68521.1 - 1.3e-18 66.4 0.6 2.2e-18 65.6 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM68521.1 - 1.1e-10 41.3 0.0 2e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM68521.1 - 7e-09 35.4 0.5 1.2e-08 34.6 0.3 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_membrane PF00664.18 CAM68522.1 - 1.8e-49 168.6 3.0 2.5e-49 168.1 2.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 CAM68522.1 - 5.9e-33 114.0 0.0 1e-32 113.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 CAM68522.1 - 2.5e-05 23.6 0.0 0.033 13.4 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CAM68522.1 - 9.8e-05 22.4 0.4 0.00042 20.3 0.3 2.0 1 1 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.4 CAM68522.1 - 0.0011 17.6 0.2 0.0019 16.8 0.2 1.3 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_22 PF13401.1 CAM68522.1 - 0.0011 19.0 0.4 0.027 14.6 0.3 2.7 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.1 CAM68522.1 - 0.0018 18.2 0.0 0.99 9.3 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CAM68522.1 - 0.0045 16.7 0.0 0.16 11.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA PF00004.24 CAM68522.1 - 0.0046 17.1 0.1 0.071 13.3 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 CAM68522.1 - 0.0083 15.5 0.2 0.34 10.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 CAM68522.1 - 0.02 14.0 0.0 0.13 11.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 CAM68522.1 - 0.024 14.1 0.0 0.059 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.1 CAM68522.1 - 0.035 14.0 0.1 0.15 12.0 0.1 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 CAM68522.1 - 0.054 14.3 0.0 0.11 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CAM68522.1 - 0.062 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_10 PF12846.2 CAM68522.1 - 0.12 11.7 0.4 0.47 9.8 0.1 1.9 2 0 0 2 2 2 0 AAA-like domain DUF87 PF01935.12 CAM68522.1 - 0.13 12.0 0.2 0.32 10.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 LSM14 PF12701.2 CAM68523.1 - 9.6e-33 111.8 0.1 1.5e-32 111.2 0.1 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 CAM68523.1 - 6.8e-06 26.5 16.0 0.0043 17.5 3.6 2.6 1 1 1 2 2 2 2 FDF domain SM-ATX PF14438.1 CAM68523.1 - 3.8e-05 23.5 0.1 6.6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain DnaJ PF00226.26 CAM68525.1 - 8.8e-06 25.3 0.2 1.6e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Y_phosphatase2 PF03162.8 CAM68526.1 - 3.3e-36 124.1 0.0 2.2e-27 95.4 0.0 2.1 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 CAM68526.1 - 0.00013 22.2 0.0 0.00022 21.5 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Ins_beta PF03488.9 CAM68527.1 - 0.075 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Nematode insulin-related peptide beta type Seryl_tRNA_N PF02403.17 CAM68528.1 - 0.02 14.9 0.3 0.025 14.5 0.2 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF2475 PF10629.4 CAM68529.1 - 0.0039 17.3 1.1 0.019 15.1 0.8 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2475) zf-C4H2 PF10146.4 CAM68529.1 - 0.36 10.8 1.9 0.27 11.2 0.2 1.6 2 0 0 2 2 2 0 Zinc finger-containing protein Raptor_N PF14538.1 CAM68530.1 - 2.5e-48 163.8 0.0 4.8e-48 162.8 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT PF02985.17 CAM68530.1 - 8.2e-05 22.3 1.9 0.082 13.0 0.1 3.4 2 0 0 2 2 2 2 HEAT repeat HEAT_2 PF13646.1 CAM68530.1 - 0.0021 18.3 0.1 0.088 13.1 0.0 2.5 2 1 1 3 3 3 2 HEAT repeats Serglycin PF04360.7 CAM68530.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Serglycin RNA_pol_Rpb2_6 PF00562.23 CAM68531.1 - 3.7e-94 315.6 0.0 5.3e-94 315.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpa2_4 PF06883.7 CAM68531.1 - 4.6e-16 58.5 0.0 1.2e-15 57.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_3 PF04565.11 CAM68531.1 - 8.9e-16 57.4 0.0 3.2e-15 55.6 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.15 CAM68531.1 - 3.3e-13 49.6 0.0 9.2e-13 48.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_1 PF04563.10 CAM68531.1 - 2.9e-08 32.8 0.0 7.1e-08 31.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase beta subunit PPR_2 PF13041.1 CAM68532.2 - 0.00054 19.8 0.3 0.0042 17.0 0.0 2.6 2 1 1 3 3 3 1 PPR repeat family PPR PF01535.15 CAM68532.2 - 0.0007 19.3 0.3 0.0058 16.5 0.0 2.4 2 0 0 2 2 2 1 PPR repeat PPR_1 PF12854.2 CAM68532.2 - 0.014 14.8 0.0 0.044 13.2 0.0 1.9 1 0 0 1 1 1 0 PPR repeat GTSE1_N PF15259.1 CAM68533.1 - 0.033 14.1 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 zf-AN1 PF01428.11 CAM68534.1 - 0.00098 18.9 25.8 0.01 15.6 6.4 2.4 2 0 0 2 2 2 2 AN1-like Zinc finger ENTH PF01417.15 CAM68536.1 - 2.7e-26 91.8 0.0 4.8e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 ENTH domain Elong_Iki1 PF10483.4 CAM68536.1 - 0.39 10.0 2.9 2.1 7.6 2.8 1.5 2 0 0 2 2 2 0 Elongator subunit Iki1 CCDC50_N PF15295.1 CAM68536.1 - 2.1 8.2 13.0 4.9 7.0 9.0 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus Alpha_kinase PF02816.13 CAM68537.2 - 2.7e-52 177.1 0.0 5e-52 176.3 0.0 1.4 1 0 0 1 1 1 1 Alpha-kinase family FtsL PF04999.8 CAM68539.1 - 0.18 11.5 0.4 0.69 9.6 0.1 2.0 2 0 0 2 2 2 0 Cell division protein FtsL SCAMP PF04144.8 CAM68540.1 - 1.9e-24 86.4 7.2 3.1e-24 85.8 5.0 1.3 1 0 0 1 1 1 1 SCAMP family eIF-5a PF01287.15 CAM68543.1 - 2.2e-24 85.1 0.1 3.1e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.7 CAM68543.1 - 0.0012 18.6 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain KOW PF00467.24 CAM68543.1 - 0.054 13.2 0.4 0.054 13.2 0.3 1.8 2 0 0 2 2 2 0 KOW motif eIF-5a PF01287.15 CAM68544.1 - 5.6e-24 83.8 0.1 8e-24 83.3 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.7 CAM68544.1 - 0.0029 17.4 0.0 0.005 16.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain KOW PF00467.24 CAM68544.1 - 0.1 12.3 0.4 0.1 12.3 0.3 1.7 2 0 0 2 2 2 0 KOW motif SNF2_N PF00176.18 CAM68545.1 - 3.6e-63 213.1 0.1 6.6e-33 113.7 0.0 3.0 2 1 0 2 2 2 2 SNF2 family N-terminal domain zf-PARP PF00645.13 CAM68545.1 - 1.1e-15 57.6 0.2 3.3e-15 56.0 0.1 1.9 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Helicase_C PF00271.26 CAM68545.1 - 5.1e-14 51.9 0.0 1.7e-13 50.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 CAM68545.1 - 5.4e-08 32.5 4.3 5.4e-08 32.5 3.0 3.0 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4 PF00097.20 CAM68545.1 - 0.0001 21.8 3.2 0.0001 21.8 2.2 3.2 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CAM68545.1 - 0.00042 20.3 1.1 0.0017 18.4 0.7 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CAM68545.1 - 0.0059 16.3 4.0 0.0059 16.3 2.8 4.0 6 0 0 6 6 5 1 zinc-RING finger domain ResIII PF04851.10 CAM68545.1 - 0.0077 16.0 0.0 6.2 6.6 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.1 CAM68545.1 - 0.0077 16.2 3.9 0.0077 16.2 2.7 3.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CAM68545.1 - 0.012 15.4 1.1 0.041 13.7 0.8 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Cytochrome-c551 PF10643.4 CAM68545.1 - 0.57 9.4 1.7 1.3 8.2 1.2 1.5 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 PP2C PF00481.16 CAM68546.1 - 3.7e-52 177.2 0.1 4.8e-52 176.8 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 CAM68546.1 - 0.00052 19.7 0.0 0.0051 16.5 0.0 2.3 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 CAM68546.1 - 0.00062 19.2 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C TIP39 PF14980.1 CAM68546.1 - 0.025 14.2 0.0 0.062 12.9 0.0 1.6 1 0 0 1 1 1 0 TIP39 peptide Luciferase_N PF05295.6 CAM68546.1 - 0.03 14.0 0.0 0.076 12.8 0.0 1.6 1 0 0 1 1 1 0 Luciferase/LBP N-terminal domain Shisa PF13908.1 CAM68548.1 - 0.0059 16.8 3.1 0.0059 16.8 2.1 1.7 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator Pdase_C33_assoc PF14756.1 CAM68548.1 - 0.04 13.6 1.0 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 Peptidase_C33-associated domain Shisa PF13908.1 CAM68549.1 - 0.87 9.7 9.9 1.8 8.7 6.9 1.6 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Ank_4 PF13637.1 CAM68550.1 - 1.1e-08 35.3 3.4 0.0039 17.6 0.0 4.8 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CAM68550.1 - 1.5e-08 34.8 1.1 0.0021 18.3 0.0 4.5 3 2 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CAM68550.1 - 0.00029 20.9 1.8 0.0072 16.5 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CAM68550.1 - 0.00059 19.8 2.3 0.035 14.3 0.0 4.8 6 1 1 7 7 7 1 Ankyrin repeat Ank PF00023.25 CAM68550.1 - 0.0078 15.9 0.1 0.0078 15.9 0.1 3.8 5 0 0 5 5 5 1 Ankyrin repeat LAT PF15234.1 CAM68550.1 - 0.13 11.6 6.0 0.34 10.3 4.2 1.7 1 0 0 1 1 1 0 Linker for activation of T-cells zf-DNL PF05180.7 CAM68551.1 - 6.8e-29 99.3 0.1 1.1e-28 98.6 0.1 1.4 1 0 0 1 1 1 1 DNL zinc finger zinc_ribbon_5 PF13719.1 CAM68551.1 - 0.063 12.8 0.3 0.13 11.8 0.0 1.6 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CAM68551.1 - 0.067 12.8 0.4 0.13 11.9 0.0 1.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_4 PF14570.1 CAM68551.1 - 0.081 12.5 0.3 0.15 11.6 0.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Tmemb_cc2 PF10267.4 CAM68551.1 - 0.15 10.6 0.3 0.19 10.2 0.2 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Cyclin_N PF00134.18 CAM68552.1 - 2.2e-06 27.2 1.3 0.0018 17.8 0.0 3.4 4 0 0 4 4 4 2 Cyclin, N-terminal domain Prefoldin_2 PF01920.15 CAM68553.1 - 1.7e-11 43.7 3.1 2.2e-11 43.4 2.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 CAM68553.1 - 4.8e-06 26.2 4.0 0.00067 19.2 0.8 2.1 2 0 0 2 2 2 2 Prefoldin subunit HR1 PF02185.11 CAM68553.1 - 0.0013 18.4 2.2 0.21 11.3 0.0 2.2 2 0 0 2 2 2 1 Hr1 repeat DUF342 PF03961.8 CAM68553.1 - 0.0078 14.6 0.9 0.0097 14.3 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF342) AAA_13 PF13166.1 CAM68553.1 - 0.013 13.9 0.9 0.016 13.6 0.6 1.0 1 0 0 1 1 1 0 AAA domain CCDC-167 PF15188.1 CAM68553.1 - 0.02 14.8 4.3 0.36 10.7 0.8 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF4140 PF13600.1 CAM68553.1 - 0.023 15.1 2.5 4 7.9 0.5 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Seryl_tRNA_N PF02403.17 CAM68553.1 - 0.028 14.4 2.7 0.98 9.4 1.2 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Ead_Ea22 PF13935.1 CAM68553.1 - 0.037 14.3 4.0 0.051 13.9 2.8 1.3 1 1 0 1 1 1 0 Ead/Ea22-like protein Troponin PF00992.15 CAM68553.1 - 0.04 13.9 1.8 0.04 13.9 1.3 1.9 2 0 0 2 2 2 0 Troponin V_ATPase_I PF01496.14 CAM68553.1 - 0.04 11.7 1.2 0.043 11.6 0.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.6 CAM68553.1 - 0.04 13.7 1.0 2.4 8.1 0.0 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.7 CAM68553.1 - 0.051 13.3 0.1 0.097 12.4 0.1 1.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cbl_N PF02262.11 CAM68553.1 - 0.077 12.7 0.0 0.13 11.9 0.0 1.4 1 1 0 1 1 1 0 CBL proto-oncogene N-terminal domain 1 Med9 PF07544.8 CAM68553.1 - 0.079 12.7 2.6 5.6 6.7 0.5 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF904 PF06005.7 CAM68553.1 - 0.086 13.1 5.6 0.86 9.9 3.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DivIC PF04977.10 CAM68553.1 - 0.087 12.3 3.2 7.8 6.0 0.0 2.2 2 0 0 2 2 2 0 Septum formation initiator DUF4600 PF15372.1 CAM68553.1 - 0.088 13.0 1.3 0.16 12.2 0.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) Occludin_ELL PF07303.8 CAM68553.1 - 0.1 13.3 2.0 1 10.1 0.0 2.1 1 1 0 2 2 2 0 Occludin homology domain Tropomyosin_1 PF12718.2 CAM68553.1 - 0.13 12.0 7.2 2.1 8.1 0.1 2.1 2 0 0 2 2 2 0 Tropomyosin like TBPIP PF07106.8 CAM68553.1 - 0.15 11.5 5.5 0.51 9.8 1.6 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 CAM68553.1 - 0.17 11.4 9.9 4.1 6.9 6.4 2.0 1 1 0 1 1 1 0 IncA protein Enkurin PF13864.1 CAM68553.1 - 0.18 12.0 2.9 2.8 8.2 0.6 2.2 2 0 0 2 2 2 0 Calmodulin-binding Spc24 PF08286.6 CAM68553.1 - 0.23 11.1 3.6 0.52 10.0 1.0 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 TPR_MLP1_2 PF07926.7 CAM68553.1 - 0.48 10.1 7.2 2.4 7.9 5.0 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4164 PF13747.1 CAM68553.1 - 1 9.5 8.3 3.2 7.9 5.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) KfrA_N PF11740.3 CAM68553.1 - 2.2 8.7 6.6 3.7 8.0 4.2 1.7 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term XhlA PF10779.4 CAM68553.1 - 2.3 8.2 4.4 24 4.9 0.1 2.2 2 0 0 2 2 2 0 Haemolysin XhlA Kdo PF06293.9 CAM68558.1 - 1.3e-06 27.5 0.0 0.0011 18.0 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CAM68558.1 - 0.00032 20.0 0.0 0.74 9.1 0.0 2.2 2 0 0 2 2 2 2 RIO1 family APH PF01636.18 CAM68558.1 - 0.0012 18.6 0.1 0.0046 16.7 0.1 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 CAM68558.1 - 0.012 14.8 0.0 0.048 12.8 0.0 1.9 1 1 0 1 1 1 0 Protein kinase domain LRR_8 PF13855.1 CAM68559.1 - 1.6e-18 66.2 3.6 1.3e-15 56.8 0.3 3.4 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 CAM68559.1 - 4.6e-12 45.2 1.6 1e-05 24.9 0.2 3.1 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CAM68559.1 - 5.1e-07 28.8 3.9 0.039 13.9 0.1 4.9 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.1 CAM68559.1 - 0.00012 21.7 0.5 0.33 11.1 0.0 4.0 3 0 0 3 3 3 1 Leucine Rich repeat LRR_9 PF14580.1 CAM68559.1 - 0.00026 20.5 0.0 0.00074 19.1 0.0 1.7 1 0 0 1 1 1 1 Leucine-rich repeat LRR_7 PF13504.1 CAM68559.1 - 0.00053 19.7 5.2 2 8.9 0.2 5.0 5 0 0 5 5 5 2 Leucine rich repeat Ribosomal_L23 PF00276.15 CAM68560.1 - 0.00057 19.7 0.4 0.00089 19.1 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L23 DUF3366 PF11846.3 CAM68561.1 - 0.044 13.6 1.7 1.7 8.4 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3366) DUF4293 PF14126.1 CAM68561.1 - 0.052 13.4 0.2 0.1 12.5 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) SPC25 PF06703.6 CAM68561.1 - 0.75 9.3 4.7 13 5.2 0.9 2.2 1 1 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF4131 PF13567.1 CAM68561.1 - 4.8 6.5 6.7 0.67 9.3 0.2 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Pro_isomerase PF00160.16 CAM68562.1 - 1.4e-44 152.0 0.0 1.5e-44 151.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SLBP_RNA_bind PF15247.1 CAM68563.1 - 3.7e-13 49.0 0.0 1.5e-12 47.1 0.0 2.0 1 1 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain Ank_4 PF13637.1 CAM68564.1 - 1.6e-23 82.5 0.1 2.4e-11 43.8 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 CAM68564.1 - 2.2e-20 71.3 3.9 7.6e-07 28.6 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 CAM68564.1 - 1.5e-19 70.1 0.0 7.4e-10 39.0 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CAM68564.1 - 2.1e-16 59.5 4.1 5.5e-08 32.8 0.1 4.4 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CAM68564.1 - 7.3e-15 53.6 0.4 9.8e-05 22.2 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat zf-RVT PF13966.1 CAM68564.1 - 0.072 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase PUB PF09409.5 CAM68566.1 - 0.026 14.2 0.0 0.086 12.6 0.0 1.8 2 0 0 2 2 2 0 PUB domain Tubulin PF00091.20 CAM68567.1 - 2.7e-72 243.1 0.0 3.8e-72 242.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CAM68567.1 - 2.7e-44 150.2 0.2 2.7e-44 150.2 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CAM68567.1 - 3.8e-06 26.9 0.0 1.4e-05 25.1 0.0 1.9 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.1 CAM68567.1 - 0.033 13.1 0.0 0.049 12.5 0.0 1.2 1 0 0 1 1 1 0 Tubulin like EF-hand_7 PF13499.1 CAM68568.1 - 1.3e-05 25.1 0.0 0.014 15.4 0.0 3.5 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.27 CAM68568.1 - 0.032 13.5 0.0 0.19 11.0 0.0 2.2 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.1 CAM68568.1 - 0.036 13.9 0.0 1.8 8.6 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain EF-hand_8 PF13833.1 CAM68568.1 - 0.053 13.1 0.0 0.33 10.5 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair Dynein_heavy PF03028.10 CAM68569.2 - 1.5e-174 581.8 1.1 5e-174 580.1 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor DHC_N1 PF08385.7 CAM68569.2 - 2.1e-127 425.9 13.3 2.1e-127 425.9 9.3 3.8 4 0 0 4 4 4 2 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 CAM68569.2 - 9.1e-117 390.0 1.4 9.1e-117 390.0 1.0 3.1 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CAM68569.2 - 7.1e-92 307.0 0.0 1.6e-91 305.9 0.0 1.6 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 CAM68569.2 - 1.1e-71 240.9 0.0 2.2e-71 239.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 CAM68569.2 - 1.8e-54 184.0 1.5 4.4e-54 182.7 1.0 1.7 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 CAM68569.2 - 1.5e-40 138.9 0.0 3.7e-40 137.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 MT PF12777.2 CAM68569.2 - 3.7e-38 131.1 8.1 3.7e-38 131.1 5.6 1.7 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 CAM68569.2 - 5.4e-14 52.1 0.0 0.002 17.8 0.0 5.5 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA PF00004.24 CAM68569.2 - 7.5e-07 29.4 1.0 0.034 14.3 0.0 5.5 5 0 0 5 5 5 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CAM68569.2 - 0.0026 18.5 0.1 0.15 12.8 0.0 3.9 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.1 CAM68569.2 - 1.8 8.6 9.4 10 6.2 0.0 5.5 7 0 0 7 7 7 0 AAA domain Complex1_LYR PF05347.10 CAM68570.1 - 8.5e-06 25.4 0.0 1.7e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CAM68570.1 - 0.00037 20.6 0.1 0.00092 19.3 0.0 1.7 2 0 0 2 2 2 1 Complex1_LYR-like 2OG-FeII_Oxy PF03171.15 CAM68572.2 - 1.8e-11 44.2 0.0 4.6e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 CAM68572.2 - 0.011 16.2 0.0 0.64 10.5 0.0 2.5 2 0 0 2 2 2 0 non-haem dioxygenase in morphine synthesis N-terminal SecE PF00584.15 CAM68573.1 - 6.3e-13 48.0 0.4 7.2e-13 47.8 0.3 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex CobD_Cbib PF03186.8 CAM68573.1 - 0.0095 15.0 0.0 0.01 14.9 0.0 1.0 1 0 0 1 1 1 1 CobD/Cbib protein NAD_binding_2 PF03446.10 CAM68574.1 - 1.1e-31 109.8 0.1 1.8e-31 109.1 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 CAM68574.1 - 5.8e-13 48.9 0.3 2e-11 44.0 0.1 2.7 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Minor_capsid_1 PF10665.4 CAM68574.1 - 0.00047 19.9 0.0 0.00088 19.0 0.0 1.4 1 0 0 1 1 1 1 Minor capsid protein F420_oxidored PF03807.12 CAM68574.1 - 0.0012 19.1 0.2 0.0084 16.5 0.0 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 CAM68574.1 - 0.0055 17.2 0.0 0.46 11.0 0.0 2.8 2 1 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold 3HCDH_N PF02737.13 CAM68574.1 - 0.025 14.2 0.0 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NPV_P10 PF05531.7 CAM68576.1 - 0.28 11.4 2.1 0.53 10.5 0.0 2.4 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Frataxin_Cyay PF01491.11 CAM68577.1 - 1.8e-28 98.4 0.0 2.4e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain CorA PF01544.13 CAM68579.1 - 2.1 7.3 3.9 1.3 8.0 0.2 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF2652 PF10851.3 CAM68580.1 - 0.00012 22.0 0.0 0.0002 21.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2652) RRM_5 PF13893.1 CAM68580.1 - 0.00027 20.7 0.0 0.00045 20.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM68580.1 - 0.00085 19.2 0.1 0.0021 17.9 0.0 1.7 1 1 1 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAM68580.1 - 0.001 18.6 0.1 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CorA PF01544.13 CAM68581.1 - 3.8e-19 68.8 0.2 1.3e-18 67.0 0.2 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Dispanin PF04505.7 CAM68581.1 - 0.2 11.2 1.2 0.57 9.7 0.7 2.0 1 1 0 1 1 1 0 Interferon-induced transmembrane protein CTDII PF01556.13 CAM68582.1 - 4.5e-23 80.9 0.0 1.3e-22 79.4 0.0 1.8 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ PF00226.26 CAM68582.1 - 1.8e-18 66.0 1.1 3.5e-18 65.0 0.7 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 CAM68582.1 - 3.5e-16 59.0 13.8 5.7e-16 58.3 9.5 1.3 1 0 0 1 1 1 1 DnaJ central domain DUF879 PF05947.7 CAM68582.1 - 0.041 12.2 0.0 0.06 11.6 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF879) DZR PF12773.2 CAM68582.1 - 0.37 10.6 11.9 12 5.8 8.3 2.3 1 1 0 1 1 1 0 Double zinc ribbon Ogr_Delta PF04606.7 CAM68582.1 - 1.4 8.6 7.9 10 5.8 0.0 3.3 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger Prok-RING_1 PF14446.1 CAM68582.1 - 1.8 8.3 11.1 0.16 11.6 1.0 2.7 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 zf-RING_3 PF14369.1 CAM68582.1 - 1.8 8.5 13.7 5.1 7.1 1.2 3.5 2 2 1 3 3 3 0 zinc-finger Terminase_GpA PF05876.7 CAM68582.1 - 5.1 5.3 5.5 8.7 4.5 3.8 1.3 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) HypA PF01155.14 CAM68582.1 - 5.2 6.7 10.5 1.9 8.2 1.2 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF164 PF02591.10 CAM68582.1 - 5.9 6.8 7.5 10 6.0 2.2 3.0 2 1 0 2 2 2 0 Putative zinc ribbon domain Kelch_4 PF13418.1 CAM68583.2 - 1.8e-06 27.5 5.4 0.00032 20.4 0.0 3.7 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CAM68583.2 - 0.00035 20.6 0.1 1.1 9.5 0.0 3.0 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.20 CAM68583.2 - 0.024 14.1 0.0 2.4 7.7 0.0 2.7 2 0 0 2 2 2 0 Kelch motif DUF4197 PF13852.1 CAM68583.2 - 0.53 9.7 0.0 0.94 8.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4197) Lebercilin PF15619.1 CAM68583.2 - 5.9 6.2 3.1 11 5.4 2.1 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Aldedh PF00171.17 CAM68584.1 - 5.2e-180 598.6 0.2 5.9e-180 598.5 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CAM68584.1 - 0.001 17.8 0.0 0.0021 16.8 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 CAM68584.1 - 0.0051 16.0 0.0 0.012 14.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) SBP_bac_3 PF00497.15 CAM68585.1 - 0.012 14.8 0.0 2.4 7.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 Mec-17 PF05301.6 CAM68587.1 - 5e-34 116.8 0.0 7e-34 116.3 0.0 1.2 1 0 0 1 1 1 1 Touch receptor neuron protein Mec-17 Acetyltransf_1 PF00583.19 CAM68587.1 - 0.0006 19.8 0.0 0.002 18.1 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CAM68587.1 - 0.05 13.7 0.0 0.089 12.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain LMBR1 PF04791.11 CAM68588.1 - 2.4e-32 112.1 29.4 1.7e-20 73.0 6.6 2.0 2 0 0 2 2 2 2 LMBR1-like membrane protein DUF3188 PF11384.3 CAM68588.1 - 0.012 15.1 0.1 0.083 12.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) DUF2721 PF11026.3 CAM68588.1 - 0.12 11.9 0.0 0.12 11.9 0.0 5.6 4 2 2 6 6 6 0 Protein of unknown function (DUF2721) DUF3810 PF12725.2 CAM68588.1 - 6.7 5.5 12.9 0.81 8.5 0.0 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF3810) ATP-synt_ab PF00006.20 CAM68590.2 - 3.3e-20 72.5 0.1 6.2e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.18 CAM68590.2 - 6.6e-14 51.8 0.2 1.3e-13 50.9 0.1 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_25 PF13481.1 CAM68590.2 - 0.0063 15.9 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 CAM68590.2 - 0.02 14.0 0.1 0.03 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 KaiC PF06745.8 CAM68590.2 - 0.11 11.6 0.8 0.15 11.1 0.6 1.2 1 0 0 1 1 1 0 KaiC NB-ARC PF00931.17 CAM68590.2 - 0.15 10.9 0.3 0.21 10.4 0.2 1.2 1 0 0 1 1 1 0 NB-ARC domain ATP-synt_ab PF00006.20 CAM68591.1 - 1.2e-64 217.7 0.1 1.1e-63 214.5 0.0 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CAM68591.1 - 8.6e-22 77.7 0.3 1.5e-21 76.9 0.2 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CAM68591.1 - 1.6e-13 50.6 0.2 3.8e-13 49.4 0.1 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_25 PF13481.1 CAM68591.1 - 0.0014 18.0 1.0 0.0059 16.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 CAM68591.1 - 0.0042 17.2 0.1 0.029 14.5 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 CAM68591.1 - 0.0047 16.0 0.1 0.0083 15.2 0.0 1.4 1 0 0 1 1 1 1 KaiC DUF258 PF03193.11 CAM68591.1 - 0.054 12.6 0.1 0.095 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NB-ARC PF00931.17 CAM68591.1 - 0.22 10.3 0.5 0.36 9.6 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain Ribosomal_S25 PF03297.10 CAM68592.1 - 2.8e-43 146.2 4.0 3.2e-43 146.0 2.7 1.0 1 0 0 1 1 1 1 S25 ribosomal protein DUF3516 PF12029.3 CAM68592.1 - 0.089 11.5 0.3 0.094 11.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) DNA_methylase PF00145.12 CAM68593.1 - 6.1e-40 137.3 0.0 4e-30 105.0 0.0 3.7 2 1 0 3 3 3 3 C-5 cytosine-specific DNA methylase WD40 PF00400.27 CAM68594.1 - 0.0015 18.3 0.5 0.088 12.7 0.0 3.5 4 0 0 4 4 4 1 WD domain, G-beta repeat PPR_3 PF13812.1 CAM68596.1 - 0.048 13.9 5.3 3.7 8.0 0.1 6.0 5 0 0 5 5 5 0 Pentatricopeptide repeat domain PPR_2 PF13041.1 CAM68596.1 - 0.61 10.1 0.0 96 3.0 0.0 3.4 3 0 0 3 3 3 0 PPR repeat family MukB PF04310.7 CAM68598.1 - 0.49 9.6 2.2 11 5.2 0.9 2.5 2 0 0 2 2 2 0 MukB N-terminal BSD PF03909.12 CAM68601.1 - 0.052 13.3 1.6 0.29 10.9 0.1 2.6 3 0 0 3 3 3 0 BSD domain Cullin PF00888.17 CAM68602.2 - 9.7e-42 143.2 0.0 5.1e-31 107.8 0.0 2.0 2 0 0 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.4 CAM68602.2 - 5.6e-13 48.5 0.0 1.8e-12 46.8 0.0 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain NPL4 PF05021.10 CAM68603.1 - 5.2e-09 35.6 0.0 8.5e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 NPL4 family FLYWCH_N PF15423.1 CAM68603.1 - 0.016 15.3 0.2 0.032 14.3 0.1 1.5 1 0 0 1 1 1 0 FLYWCH-type zinc finger-containing protein PRP38 PF03371.10 CAM68604.1 - 3e-05 23.7 0.0 4.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 PRP38 family MbeB_N PF04837.7 CAM68604.1 - 0.036 14.1 0.0 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 MbeB-like, N-term conserved region PPP4R2 PF09184.6 CAM68605.1 - 0.0018 17.8 0.1 0.0057 16.2 0.0 1.7 1 1 1 2 2 2 1 PPP4R2 Metallophos PF00149.23 CAM68606.1 - 1.8e-41 141.7 1.6 2.5e-41 141.3 1.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase GIY-YIG PF01541.19 CAM68607.1 - 4.6e-07 30.0 0.0 8.9e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain T5orf172 PF10544.4 CAM68607.1 - 0.029 14.7 0.0 0.14 12.5 0.0 2.1 2 0 0 2 2 2 0 T5orf172 domain Sec23_trunk PF04811.10 CAM68608.1 - 3.6e-39 134.5 0.0 5.7e-39 133.9 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 CAM68608.1 - 4.8e-17 62.2 0.1 9e-17 61.3 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.10 CAM68608.1 - 7.7e-17 60.6 0.0 1.3e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 CAM68608.1 - 8.9e-14 50.7 1.7 3e-13 49.0 0.9 2.1 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger VID27 PF08553.5 CAM68609.2 - 3.9 5.5 3.8 6 4.9 2.6 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Peptidase_M30 PF10460.4 CAM68610.1 - 0.36 9.6 0.9 1.5 7.6 0.2 2.0 2 0 0 2 2 2 0 Peptidase M30 TAP42 PF04177.7 CAM68611.1 - 8.6e-28 97.2 12.2 4.5e-15 55.4 9.0 2.3 2 1 0 2 2 2 2 TAP42-like family OmpH PF03938.9 CAM68611.1 - 2.8 7.8 9.9 4.4 7.2 1.3 2.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) HAUS6_N PF14661.1 CAM68612.1 - 0.025 13.9 0.5 0.038 13.3 0.3 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus RMF PF04957.7 CAM68612.1 - 0.15 11.7 1.2 16 5.2 0.0 2.3 2 0 0 2 2 2 0 Ribosome modulation factor DUF3499 PF12005.3 CAM68612.1 - 8.3 6.6 6.6 20 5.3 2.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3499) ATP_bind_1 PF03029.12 CAM68613.1 - 2.5e-61 207.2 0.0 2.8e-61 207.0 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 CAM68613.1 - 9.3e-06 26.4 0.0 1.9e-05 25.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CAM68613.1 - 0.00051 19.5 0.0 0.00077 18.9 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 CAM68613.1 - 0.00087 19.4 0.0 0.0014 18.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CAM68613.1 - 0.0013 19.0 0.0 0.0028 17.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.18 CAM68613.1 - 0.0015 18.4 0.0 0.0058 16.5 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_19 PF13245.1 CAM68613.1 - 0.0019 17.9 0.0 0.0033 17.1 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain SRP54 PF00448.17 CAM68613.1 - 0.0019 17.6 0.1 0.0045 16.4 0.0 1.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_30 PF13604.1 CAM68613.1 - 0.0019 17.7 0.3 0.0027 17.3 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CAM68613.1 - 0.002 18.3 0.0 0.0039 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 CAM68613.1 - 0.0064 15.9 0.0 1.7 8.1 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation CbiA PF01656.18 CAM68613.1 - 0.0065 15.8 0.0 0.016 14.6 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.1 CAM68613.1 - 0.0079 15.6 0.0 0.048 13.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CAM68613.1 - 0.017 14.6 0.1 0.035 13.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 CAM68613.1 - 0.019 14.6 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 CAM68613.1 - 0.034 14.1 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CAM68613.1 - 0.038 14.1 0.6 0.22 11.7 0.0 2.4 2 1 1 3 3 3 0 RNA helicase AAA_16 PF13191.1 CAM68613.1 - 0.038 13.9 0.0 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 CAM68613.1 - 0.053 12.7 0.0 0.14 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 CAM68613.1 - 0.057 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 CAM68613.1 - 0.061 12.8 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CAM68613.1 - 0.061 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 CAM68613.1 - 0.11 11.5 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain GTP_EFTU PF00009.22 CAM68613.1 - 0.11 11.8 0.0 1.8 7.9 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_5 PF07728.9 CAM68613.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ArgK PF03308.11 CAM68613.1 - 0.15 10.7 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 ArgK protein Surp PF01805.15 CAM68614.1 - 2.1e-14 52.8 2.0 6.1e-11 41.8 0.1 2.4 2 0 0 2 2 2 2 Surp module DUF2362 PF10154.4 CAM68614.1 - 0.15 10.6 0.2 0.23 10.1 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) DNA_pol_E_B PF04042.11 CAM68615.1 - 4.7e-27 94.5 1.1 2e-14 53.3 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase alpha/epsilon subunit B Ras PF00071.17 CAM68616.1 - 1.5e-50 170.7 0.0 1.9e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAM68616.1 - 6.4e-17 62.1 0.0 1.2e-16 61.2 0.0 1.5 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 CAM68616.1 - 4.4e-11 42.3 0.0 5.9e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 CAM68616.1 - 0.00027 21.0 0.2 0.0017 18.4 0.1 2.0 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 CAM68616.1 - 0.00037 19.6 0.0 0.00046 19.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region cobW PF02492.14 CAM68616.1 - 0.015 14.7 0.1 2.6 7.4 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.15 CAM68616.1 - 0.026 13.1 1.6 1 7.9 0.1 2.9 2 1 1 3 3 3 0 G-protein alpha subunit AAA_22 PF13401.1 CAM68616.1 - 0.027 14.5 0.2 0.28 11.3 0.0 2.4 3 0 0 3 3 3 0 AAA domain GTP_EFTU PF00009.22 CAM68616.1 - 0.033 13.6 0.6 0.3 10.5 0.4 2.1 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 CAM68616.1 - 0.037 13.9 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.7 CAM68616.1 - 0.073 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein ATP_bind_1 PF03029.12 CAM68616.1 - 0.12 11.8 0.4 11 5.4 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.13 CAM68616.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Septin PduV-EutP PF10662.4 CAM68616.1 - 0.14 11.6 0.0 1.1 8.7 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation KaiC PF06745.8 CAM68616.1 - 0.17 11.0 0.1 0.36 9.8 0.1 1.5 1 1 0 1 1 1 0 KaiC Cluap1 PF10234.4 CAM68617.1 - 3.1e-101 338.0 12.4 4.1e-101 337.6 8.6 1.2 1 0 0 1 1 1 1 Clusterin-associated protein-1 Lectin_N PF03954.9 CAM68617.1 - 0.11 11.9 3.4 0.055 12.8 0.3 2.0 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain BRE1 PF08647.6 CAM68617.1 - 0.88 9.5 20.9 0.051 13.5 6.6 2.9 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase RNase_T PF00929.19 CAM68618.1 - 2.8e-05 24.4 0.0 4.8e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DUF1295 PF06966.7 CAM68620.1 - 5.7e-08 32.3 1.4 7.1e-08 32.0 0.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.8 CAM68620.1 - 4.6e-05 23.4 1.3 4.6e-05 23.4 0.9 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.11 CAM68620.1 - 0.0025 17.5 1.1 0.0042 16.8 0.5 1.6 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Rod_cone_degen PF15201.1 CAM68620.1 - 0.031 14.0 1.8 0.055 13.3 0.6 1.9 2 0 0 2 2 2 0 Progressive rod-cone degeneration RF-1 PF00472.15 CAM68621.1 - 1.1e-30 105.7 0.1 2.3e-30 104.7 0.0 1.5 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 CAM68621.1 - 6.2e-15 54.9 0.2 1.3e-14 53.8 0.1 1.5 1 0 0 1 1 1 1 PCRF domain SFTA2 PF15210.1 CAM68621.1 - 0.042 13.4 0.1 7.9 6.1 0.1 2.5 2 0 0 2 2 2 0 Surfactant-associated protein 2 DUF1126 PF06565.7 CAM68622.1 - 1.1e-32 111.1 0.1 4.2e-10 38.9 0.0 3.8 3 0 0 3 3 3 3 Repeat of unknown function (DUF1126) EF-hand_7 PF13499.1 CAM68622.1 - 0.023 14.8 0.5 1.3 9.1 0.0 3.2 2 1 0 2 2 2 0 EF-hand domain pair Cyclin_N PF00134.18 CAM68623.1 - 3e-38 130.2 0.7 4.5e-38 129.6 0.5 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CAM68623.1 - 7.5e-14 51.6 0.0 1.3e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain Rhodopsin_N PF10413.4 CAM68623.1 - 0.0017 17.9 0.1 0.0036 16.9 0.0 1.5 1 0 0 1 1 1 1 Amino terminal of the G-protein receptor rhodopsin NfI_DNAbd_pre-N PF10524.4 CAM68623.1 - 0.031 13.8 0.0 0.073 12.6 0.0 1.6 1 0 0 1 1 1 0 Nuclear factor I protein pre-N-terminus Peptidase_C2 PF00648.16 CAM68624.1 - 5.3e-52 176.6 0.1 8.4e-52 176.0 0.1 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 CAM68624.1 - 7.8e-26 90.0 0.3 2.7e-25 88.3 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1935) Rab3-GTPase_cat PF13890.1 CAM68625.1 - 1.7e-48 164.0 0.1 3.6e-48 163.0 0.0 1.5 1 0 0 1 1 1 1 Rab3 GTPase-activating protein catalytic subunit Nol1_Nop2_Fmu PF01189.12 CAM68626.1 - 5.4e-18 65.3 0.0 8.1e-12 45.0 0.0 2.2 2 0 0 2 2 2 2 NOL1/NOP2/sun family PUA PF01472.15 CAM68626.1 - 2.5e-07 30.2 0.1 5.6e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 PUA domain GEMIN8 PF15348.1 CAM68627.1 - 0.047 13.7 0.2 3.9 7.4 0.6 2.5 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 Pkinase PF00069.20 CAM68628.1 - 2.1e-44 151.6 0.0 2.8e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM68628.1 - 2.7e-30 105.3 0.0 3.6e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM68628.1 - 0.0009 18.2 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CAM68628.1 - 0.012 15.3 2.0 0.059 13.0 0.1 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CAM68628.1 - 0.21 10.8 0.0 0.35 10.1 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL ABC_ATPase PF09818.4 CAM68630.1 - 8.3e-170 565.1 0.0 1.1e-169 564.8 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.1 CAM68630.1 - 0.041 14.2 0.0 0.069 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CAM68630.1 - 0.12 11.7 0.1 0.26 10.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain zf-Tim10_DDP PF02953.10 CAM68631.1 - 1.4e-05 24.2 0.1 1.8e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Pkinase PF00069.20 CAM68632.1 - 3.1e-29 101.9 0.0 3.2e-16 59.2 0.0 3.6 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CAM68632.1 - 1.1e-06 27.9 0.0 0.18 10.8 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase RIO1 PF01163.17 CAM68632.1 - 0.17 11.2 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.6 CAM68632.1 - 0.22 10.2 0.1 0.35 9.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TRAPPC-Trs85 PF12739.2 CAM68633.1 - 7.8e-33 113.7 1.4 1.4e-32 112.9 1.0 1.3 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_11 PF13414.1 CAM68633.1 - 6.9e-05 22.4 1.7 0.00096 18.7 0.1 2.6 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.1 CAM68633.1 - 0.01 15.7 4.5 0.18 11.7 0.7 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 CAM68633.1 - 0.18 11.4 1.4 2.5 7.8 0.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 CAM68633.1 - 9.1 6.4 8.4 6.4 6.9 1.4 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.20 CAM68634.1 - 4.5e-34 117.7 0.1 4.8e-28 98.0 0.0 2.2 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAM68634.1 - 5.6e-12 45.2 0.0 1.4e-07 30.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CAM68634.1 - 0.029 14.0 0.1 0.09 12.4 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 CAM68634.1 - 0.12 11.2 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like BRCT PF00533.21 CAM68635.1 - 3.9e-05 23.7 0.0 0.0041 17.2 0.0 3.6 4 0 0 4 4 4 1 BRCA1 C Terminus (BRCT) domain WD40 PF00400.27 CAM68636.1 - 1.9e-17 62.3 10.9 0.095 12.6 0.0 9.7 11 0 0 11 11 11 7 WD domain, G-beta repeat JAB PF01398.16 CAM68637.1 - 0.0002 21.1 0.0 0.00059 19.5 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DAGAT PF03982.8 CAM68639.1 - 8.9e-79 264.2 0.1 1.1e-78 263.9 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase KOW PF00467.24 CAM68640.1 - 0.042 13.5 1.2 0.12 12.1 0.9 1.8 1 0 0 1 1 1 0 KOW motif DUF1016 PF06250.6 CAM68640.1 - 0.078 11.9 0.5 0.15 11.0 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1016) COX6B PF02297.12 CAM68641.1 - 0.0063 16.4 5.6 0.065 13.2 3.3 2.0 1 1 1 2 2 2 2 Cytochrome oxidase c subunit VIb CHCH PF06747.8 CAM68641.1 - 0.12 12.3 5.3 0.49 10.3 0.5 2.3 2 0 0 2 2 2 0 CHCH domain EFP_N PF08207.7 CAM68642.1 - 2e-05 24.3 0.3 3.3e-05 23.6 0.2 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain HORMA PF02301.13 CAM68644.1 - 1.1e-37 129.6 0.0 1.2e-37 129.4 0.0 1.0 1 0 0 1 1 1 1 HORMA domain TPR_12 PF13424.1 CAM68645.1 - 4e-12 45.8 19.1 1.3e-05 25.0 1.3 5.0 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 CAM68645.1 - 5e-06 26.0 2.7 0.61 10.1 0.1 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 CAM68645.1 - 0.0023 17.5 4.7 6.3 6.5 0.2 4.5 4 0 0 4 4 4 2 TPR repeat TPR_1 PF00515.23 CAM68645.1 - 0.58 9.8 2.8 17 5.1 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DnaJ PF00226.26 CAM68646.1 - 5.8e-06 25.9 2.0 2.6e-05 23.8 1.4 2.0 1 1 0 1 1 1 1 DnaJ domain DUF4407 PF14362.1 CAM68646.1 - 0.00026 20.0 0.1 0.00034 19.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) HSCB_C PF07743.8 CAM68646.1 - 0.0094 16.3 0.3 0.031 14.7 0.0 2.1 3 0 0 3 3 3 1 HSCB C-terminal oligomerisation domain LRR_9 PF14580.1 CAM68647.1 - 4e-12 46.0 0.0 7.1e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 CAM68647.1 - 1.7e-11 43.4 0.1 2.3e-07 30.2 0.0 3.4 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM68647.1 - 6.9e-06 25.7 5.1 5.5e-05 22.8 0.5 2.8 2 1 0 2 2 2 1 Leucine rich repeat LRR_6 PF13516.1 CAM68647.1 - 7.4e-05 22.4 0.1 12 6.3 0.0 3.8 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.28 CAM68647.1 - 8.7e-05 22.0 1.1 4.7 7.6 0.0 4.5 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 CAM68647.1 - 0.0058 16.6 4.7 4.9 7.7 0.0 4.5 4 0 0 4 4 4 1 Leucine rich repeat LSM PF01423.17 CAM68648.1 - 4.3e-13 48.5 0.0 5.5e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CAM68648.1 - 0.0097 15.8 0.3 0.02 14.7 0.1 1.6 1 1 1 2 2 2 1 Ataxin 2 SM domain Transket_pyr PF02779.19 CAM68649.1 - 8.8e-44 149.1 0.0 1.3e-43 148.6 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CAM68649.1 - 1.3e-37 128.4 0.1 4.3e-37 126.8 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain PSK_trans_fac PF07704.6 CAM68649.1 - 0.06 14.0 0.3 0.15 12.7 0.2 1.7 1 0 0 1 1 1 0 Rv0623-like transcription factor YycC PF14174.1 CAM68651.1 - 0.05 13.2 0.1 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 YycC-like protein DUF1935 PF09149.5 CAM68653.1 - 1.9e-26 92.0 0.0 2.3e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Steroid_dh PF02544.11 CAM68655.1 - 1.7e-24 86.3 2.4 2.7e-24 85.6 1.7 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 CAM68655.1 - 6.8e-05 22.2 0.9 0.00012 21.4 0.5 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) FA_desaturase PF00487.19 CAM68655.1 - 0.019 14.3 2.2 0.028 13.8 1.5 1.3 1 0 0 1 1 1 0 Fatty acid desaturase PEMT PF04191.8 CAM68655.1 - 0.023 14.7 5.0 0.081 13.0 0.6 2.3 1 1 1 2 2 2 0 Phospholipid methyltransferase ubiquitin PF00240.18 CAM68655.1 - 0.14 11.5 0.0 8.5 5.8 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin family ATP-grasp_4 PF13535.1 CAM68656.1 - 2.2e-15 56.8 0.0 7e-15 55.2 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CAM68656.1 - 1.1e-14 54.3 0.0 2.1e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus SET PF00856.23 CAM68656.1 - 2.6e-05 24.5 0.1 0.0001 22.6 0.0 2.0 2 0 0 2 2 2 1 SET domain RimK PF08443.6 CAM68656.1 - 5.1e-05 22.8 0.0 0.00022 20.7 0.0 1.9 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 CAM68656.1 - 5.3e-05 23.1 0.0 0.00023 21.0 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CAM68656.1 - 0.0013 17.5 0.0 0.29 9.8 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 CAM68656.1 - 0.0044 16.3 0.0 0.0076 15.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.1 CAM68656.1 - 0.071 12.1 0.0 0.31 10.1 0.0 2.0 3 0 0 3 3 3 0 Sugar-transfer associated ATP-grasp GARS_A PF01071.14 CAM68656.1 - 0.12 11.8 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Surp PF01805.15 CAM68656.1 - 2.1 8.0 5.0 6.1 6.5 1.0 2.8 2 1 1 3 3 3 0 Surp module CHAP PF05257.11 CAM68657.1 - 5.8e-07 29.2 2.0 0.00012 21.6 0.2 2.5 2 1 0 2 2 2 2 CHAP domain 2OG-FeII_Oxy_2 PF13532.1 CAM68658.1 - 0.12 12.2 0.0 0.43 10.3 0.0 1.9 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Thioredoxin PF00085.15 CAM68659.1 - 0.0011 18.6 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin SLBP_RNA_bind PF15247.1 CAM68661.1 - 3e-22 78.1 2.8 7.5e-22 76.8 2.0 1.6 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain Not3 PF04065.10 CAM68662.1 - 6.9e-73 244.7 23.3 1.3e-72 243.8 16.1 1.5 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 CAM68662.1 - 3.4e-35 120.8 8.2 3.4e-35 120.8 5.7 2.6 3 0 0 3 3 3 1 NOT2 / NOT3 / NOT5 family WD40 PF00400.27 CAM68663.1 - 6.1e-21 73.4 1.0 0.0031 17.3 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat TPM PF04536.9 CAM68664.1 - 1.7e-16 60.1 0.0 3e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase Thioredoxin_3 PF13192.1 CAM68664.1 - 0.087 12.6 0.9 12 5.7 0.1 3.5 3 0 0 3 3 3 0 Thioredoxin domain zf-IS66 PF13005.2 CAM68664.1 - 0.78 9.7 0.0 0.78 9.7 0.0 3.5 4 0 0 4 4 4 0 zinc-finger binding domain of transposase IS66 DUF2387 PF09526.5 CAM68664.1 - 3.2 7.7 9.4 6.3 6.7 3.8 2.6 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) Vps55 PF04133.9 CAM68666.1 - 6.6e-31 106.5 1.9 7.3e-31 106.4 1.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Tetraspannin PF00335.15 CAM68666.1 - 0.035 13.3 4.2 0.059 12.6 2.9 1.4 1 1 0 1 1 1 0 Tetraspanin family Ycf66_N PF07444.6 CAM68666.1 - 0.04 13.6 1.4 0.04 13.6 1.0 1.9 2 0 0 2 2 2 0 Ycf66 protein N-terminus MARVEL PF01284.18 CAM68666.1 - 1.3 8.7 10.4 2.2 8.0 1.8 2.1 2 0 0 2 2 2 0 Membrane-associating domain DUF308 PF03729.8 CAM68666.1 - 2.3 8.2 15.8 9 6.3 0.5 2.5 2 1 0 2 2 2 0 Short repeat of unknown function (DUF308) DUF2372 PF10178.4 CAM68667.1 - 0.0024 17.9 0.0 0.0044 17.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2372) DUF3774 PF12609.3 CAM68667.1 - 0.093 13.5 0.1 0.29 12.0 0.0 2.0 2 1 0 2 2 2 0 Wound-induced protein DFP PF04127.10 CAM68668.1 - 7.8e-20 71.2 0.0 4.3e-09 36.2 0.0 2.3 1 1 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein DNA_repr_REX1B PF14966.1 CAM68669.1 - 0.0081 16.5 3.1 0.036 14.4 0.5 2.2 2 0 0 2 2 2 1 DNA repair REX1-B DASH_Dad3 PF08656.5 CAM68669.1 - 0.04 13.6 0.0 0.091 12.4 0.0 1.6 1 0 0 1 1 1 0 DASH complex subunit Dad3 TPR_12 PF13424.1 CAM68670.1 - 6.4e-12 45.2 25.3 1e-05 25.3 1.0 3.6 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 CAM68670.1 - 0.0062 16.0 9.9 0.067 12.8 0.0 5.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 CAM68670.1 - 0.0086 15.8 18.9 0.017 14.8 0.2 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat Tcf25 PF04910.9 CAM68670.1 - 0.015 14.2 0.8 0.023 13.6 0.6 1.2 1 0 0 1 1 1 0 Transcriptional repressor TCF25 TPR_8 PF13181.1 CAM68670.1 - 0.02 14.6 6.4 0.7 9.8 0.1 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 CAM68670.1 - 0.095 12.3 21.9 1.3 8.7 0.3 4.7 1 1 2 4 4 4 0 TPR repeat TPR_2 PF07719.12 CAM68670.1 - 0.21 11.5 0.1 0.21 11.5 0.1 6.7 5 1 2 7 7 7 0 Tetratricopeptide repeat Foie-gras_1 PF11817.3 CAM68670.1 - 0.67 9.3 7.9 4.3 6.7 5.5 2.1 1 1 0 1 1 1 0 Foie gras liver health family 1 TPR_16 PF13432.1 CAM68670.1 - 0.81 10.4 30.0 0.5 11.1 3.6 4.5 3 2 1 4 4 4 0 Tetratricopeptide repeat Apc5 PF12862.2 CAM68670.1 - 4.4 7.1 12.9 2.2 8.1 0.2 3.5 2 2 1 3 3 3 0 Anaphase-promoting complex subunit 5 RRM_1 PF00076.17 CAM68671.1 - 0.038 13.6 0.0 0.066 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kinesin PF00225.18 CAM68673.1 - 4.4e-79 265.6 0.2 4.4e-79 265.6 0.1 1.9 2 0 0 2 2 2 1 Kinesin motor domain DUF342 PF03961.8 CAM68673.1 - 0.0014 17.1 5.0 0.0029 16.0 3.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF342) AAA_16 PF13191.1 CAM68673.1 - 0.026 14.4 7.9 2.5 8.0 0.0 4.0 3 1 0 3 3 3 0 AAA ATPase domain ResIII PF04851.10 CAM68673.1 - 0.068 12.9 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF445 PF04286.7 CAM68673.1 - 0.3 10.5 6.8 0.61 9.5 3.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF445) Acylphosphatase PF00708.13 CAM68674.1 - 3.9e-24 84.5 0.0 5.8e-24 84.0 0.0 1.2 1 0 0 1 1 1 1 Acylphosphatase Kinesin PF00225.18 CAM68675.1 - 5.5e-102 340.9 0.0 1e-101 340.0 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain AAA_22 PF13401.1 CAM68675.1 - 0.19 11.8 3.5 0.24 11.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain Pkinase PF00069.20 CAM68677.1 - 1.3e-56 191.6 0.0 3.7e-42 144.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAM68677.1 - 1.5e-32 112.6 0.0 7.4e-24 84.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CAM68677.1 - 0.00034 19.6 0.0 0.036 13.0 0.0 2.4 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 CAM68677.1 - 0.0054 16.4 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CAM68677.1 - 0.008 15.2 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CAM68677.1 - 0.037 13.3 0.0 0.061 12.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Iso_dh PF00180.15 CAM68677.1 - 0.16 10.8 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Isocitrate/isopropylmalate dehydrogenase YrbL-PhoP_reg PF10707.4 CAM68677.1 - 0.18 11.1 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 CAM68677.1 - 0.21 11.1 0.0 0.36 10.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase HpcH_HpaI PF03328.9 CAM68679.1 - 5.2e-54 182.4 0.0 6.1e-54 182.2 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DHQS PF01959.11 CAM68679.1 - 0.01 14.5 0.0 0.015 13.9 0.0 1.2 1 0 0 1 1 1 0 3-dehydroquinate synthase (EC 4.6.1.3) rRNA_methylase PF06962.7 CAM68679.1 - 0.03 14.0 0.0 0.072 12.7 0.0 1.6 2 0 0 2 2 2 0 Putative rRNA methylase AAA_16 PF13191.1 CAM68680.1 - 0.00011 22.2 0.0 0.00018 21.5 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 CAM68680.1 - 0.0019 17.2 0.0 0.092 11.8 0.0 2.3 1 1 0 1 1 1 1 Zeta toxin Rad17 PF03215.10 CAM68680.1 - 0.0087 14.7 0.1 0.014 14.1 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein SRP54 PF00448.17 CAM68680.1 - 0.0097 15.3 0.5 0.065 12.6 0.2 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_17 PF13207.1 CAM68680.1 - 0.01 16.6 0.0 0.049 14.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 CAM68680.1 - 0.018 14.6 0.0 0.042 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF1456 PF07308.8 CAM68680.1 - 0.027 14.5 1.6 0.11 12.5 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1456) PIF1 PF05970.9 CAM68680.1 - 0.045 12.6 0.0 0.073 12.0 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_18 PF13238.1 CAM68680.1 - 0.053 13.8 0.1 0.13 12.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain Ribosomal_S7 PF00177.16 CAM68680.1 - 0.12 11.9 0.0 0.79 9.2 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S7p/S5e NIF PF03031.13 CAM68681.1 - 1.9e-47 160.8 0.1 2.9e-47 160.3 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase G-alpha PF00503.15 CAM68681.1 - 0.045 12.4 0.0 0.074 11.7 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit SNF2_N PF00176.18 CAM68683.1 - 9.4e-47 159.2 0.1 1.4e-46 158.6 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CAM68683.1 - 4.6e-11 42.4 0.0 1.1e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PHD PF00628.24 CAM68683.1 - 9.9e-07 28.3 13.4 0.0025 17.4 2.3 2.6 2 0 0 2 2 2 2 PHD-finger HDA2-3 PF11496.3 CAM68683.1 - 3.6e-05 22.7 0.0 8.6e-05 21.4 0.0 1.5 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 CAM68683.1 - 6.6e-05 22.4 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CAM68683.1 - 0.0028 17.5 0.0 0.0058 16.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-PHD-like PF15446.1 CAM68683.1 - 0.0079 15.5 7.1 0.038 13.2 0.5 2.5 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain SpoIIE PF07228.7 CAM68684.1 - 2.6e-15 56.6 0.2 2.8e-14 53.2 0.1 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 CAM68684.1 - 5.6e-06 25.9 0.1 1.2e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 CAM68684.1 - 0.00016 21.2 0.0 0.0029 17.0 0.0 2.2 2 0 0 2 2 2 1 Protein phosphatase 2C Rieske_2 PF13806.1 CAM68685.1 - 2.8e-07 30.1 0.0 4.8e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.21 CAM68685.1 - 1.6e-06 27.5 0.3 3.2e-06 26.6 0.2 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain NAD_binding_1 PF00175.16 CAM68685.1 - 9.2e-05 22.9 0.0 0.056 14.0 0.0 2.6 1 1 1 2 2 2 2 Oxidoreductase NAD-binding domain Dak1_2 PF13684.1 CAM68685.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family GTP_EFTU PF00009.22 CAM68686.1 - 2.5e-47 160.7 0.0 6.2e-47 159.4 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 CAM68686.1 - 1.3e-14 53.7 0.0 3.1e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.13 CAM68686.1 - 5.9e-08 32.2 0.0 1.3e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.20 CAM68686.1 - 2e-07 31.0 0.1 4.4e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 CAM68686.1 - 0.0005 19.8 0.1 0.0027 17.4 0.0 2.1 2 0 0 2 2 2 1 Elongation Factor G, domain II cobW PF02492.14 CAM68686.1 - 0.058 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 CAM68686.1 - 0.094 13.2 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Ras PF00071.17 CAM68686.1 - 0.11 11.9 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 Ras family Atx10homo_assoc PF09759.4 CAM68686.1 - 0.14 11.9 0.2 0.3 10.8 0.1 1.5 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain SRPRB PF09439.5 CAM68686.1 - 0.15 11.2 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit mRNA_triPase PF02940.10 CAM68688.1 - 7.1e-36 123.9 0.0 9.6e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain TPR_11 PF13414.1 CAM68689.1 - 7.9e-23 79.8 29.1 2.2e-07 30.4 1.2 4.6 1 1 5 6 6 6 6 TPR repeat TPR_2 PF07719.12 CAM68689.1 - 2.4e-18 64.5 23.2 0.0041 16.9 0.0 7.2 6 1 1 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.23 CAM68689.1 - 4.4e-13 48.2 18.0 0.0003 20.2 0.1 7.0 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 CAM68689.1 - 1.4e-10 40.9 14.9 1e-05 25.3 0.4 4.7 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 CAM68689.1 - 4.5e-10 39.9 27.4 0.0066 17.1 0.5 4.7 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 CAM68689.1 - 1.6e-09 37.5 9.3 0.031 14.8 0.1 5.8 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 CAM68689.1 - 7.1e-08 31.6 15.8 0.0035 17.0 0.1 6.6 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 CAM68689.1 - 5e-07 29.9 7.6 0.23 11.7 0.0 4.7 2 2 2 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 CAM68689.1 - 0.00022 21.3 17.3 0.034 14.2 0.5 4.5 2 1 4 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 CAM68689.1 - 0.00056 19.9 7.8 0.17 12.1 0.0 6.0 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 CAM68689.1 - 0.0039 17.5 6.9 19 5.9 0.0 5.4 5 1 0 5 5 4 0 Tetratricopeptide repeat zf-CCHC PF00098.18 CAM68689.1 - 0.0045 16.8 0.6 0.0088 15.9 0.4 1.5 1 0 0 1 1 1 1 Zinc knuckle Fis1_TPR_C PF14853.1 CAM68689.1 - 0.047 13.5 2.5 2.2 8.2 0.0 3.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat FAT PF02259.18 CAM68689.1 - 0.12 11.2 1.6 2 7.2 0.1 2.3 1 1 0 2 2 2 0 FAT domain TPR_10 PF13374.1 CAM68689.1 - 0.17 11.9 8.8 0.49 10.3 0.2 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 CAM68689.1 - 0.75 9.6 6.3 5.9 6.8 0.3 4.3 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.7 CAM68689.1 - 0.81 9.5 3.9 15 5.5 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat KBP_C PF12309.3 CAM68690.1 - 1.5e-94 317.0 0.0 3.8e-93 312.3 0.0 2.3 2 0 0 2 2 2 1 KIF-1 binding protein C terminal NRN1 PF15056.1 CAM68690.1 - 0.076 12.9 0.2 0.26 11.2 0.1 1.9 1 0 0 1 1 1 0 Neuritin protein family TPR_7 PF13176.1 CAM68690.1 - 0.1 12.4 4.0 4.1 7.4 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat eIF3_subunit PF08597.5 CAM68691.1 - 9.6e-07 28.6 15.2 2.1e-06 27.5 10.5 1.6 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF3987 PF13148.1 CAM68691.1 - 2.4 6.6 7.6 0.74 8.3 3.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) CoA_binding PF02629.14 CAM68692.1 - 1.4e-26 92.7 2.4 1.4e-26 92.7 1.7 2.1 3 0 0 3 3 3 1 CoA binding domain Ligase_CoA PF00549.14 CAM68692.1 - 6.8e-23 80.9 0.7 1.1e-22 80.3 0.1 1.6 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.1 CAM68692.1 - 7.6e-09 35.2 0.0 1.5e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 CAM68692.1 - 0.00037 20.6 0.1 0.00078 19.5 0.1 1.6 1 0 0 1 1 1 1 CoA binding domain BRO1 PF03097.13 CAM68694.1 - 2.9e-25 88.8 0.1 3.6e-25 88.5 0.1 1.1 1 0 0 1 1 1 1 BRO1-like domain KIX PF02172.11 CAM68694.1 - 0.064 13.3 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 KIX domain BORA_N PF15280.1 CAM68695.2 - 0.025 13.9 0.7 0.039 13.2 0.5 1.3 1 0 0 1 1 1 0 Protein aurora borealis N-terminus HH_signal PF01085.13 CAM68695.2 - 0.1 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Hedgehog amino-terminal signalling domain Rad60-SLD PF11976.3 CAM68696.1 - 8.4e-06 25.3 0.5 1.4e-05 24.6 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CAM68696.1 - 0.00014 21.2 0.2 0.00024 20.4 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family MobB PF03205.9 CAM68697.1 - 2.1e-05 24.2 0.0 3.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 CAM68697.1 - 0.00063 19.2 0.1 0.0048 16.3 0.0 2.0 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_19 PF13245.1 CAM68697.1 - 0.13 12.0 0.7 0.29 10.9 0.5 1.5 1 0 0 1 1 1 0 Part of AAA domain Sec1 PF00995.18 CAM68698.1 - 1.9e-79 267.8 0.0 2.4e-79 267.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DnaJ PF00226.26 CAM68699.1 - 3e-24 84.5 2.9 6.5e-24 83.4 2.0 1.6 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.3 CAM68699.1 - 1.8e-09 37.4 4.9 3.6e-09 36.4 3.4 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CAM68699.1 - 4.5e-08 33.0 3.1 8e-08 32.2 2.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CAM68699.1 - 5.4e-05 23.2 0.5 0.00015 21.7 0.1 1.9 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.7 CAM68699.1 - 0.019 14.7 0.2 0.019 14.7 0.1 1.8 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.1 CAM68699.1 - 0.041 14.2 1.3 0.13 12.6 0.9 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 CAM68699.1 - 0.056 13.8 1.8 0.15 12.4 1.2 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type Evr1_Alr PF04777.8 CAM68699.1 - 0.17 11.8 2.2 5.6 6.9 0.2 2.5 2 0 0 2 2 2 0 Erv1 / Alr family Caldesmon PF02029.10 CAM68699.1 - 0.17 10.2 21.0 0.35 9.2 14.6 1.5 1 0 0 1 1 1 0 Caldesmon zf-C2H2_6 PF13912.1 CAM68699.1 - 0.24 11.3 2.1 0.24 11.3 0.3 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger ParcG PF10274.4 CAM68700.1 - 7e-79 263.9 0.0 8.3e-79 263.7 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein GSK-3_bind PF05350.7 CAM68700.1 - 3.5 7.0 6.5 13 5.1 0.0 2.2 2 0 0 2 2 2 0 Glycogen synthase kinase-3 binding PCI PF01399.22 CAM68701.1 - 3.3e-06 27.3 0.0 9.2e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 PCI domain TPR_16 PF13432.1 CAM68701.1 - 0.38 11.4 9.0 8.1 7.2 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 CAM68701.1 - 4.9 8.0 11.8 28 5.7 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF650 PF04894.7 CAM68702.1 - 0.019 14.4 0.1 0.036 13.5 0.0 1.5 1 0 0 1 1 1 0 Archaeal protein of unknown function (DUF650) DUF1664 PF07889.7 CAM68702.1 - 0.86 9.4 5.0 1.8 8.4 0.8 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Remorin_C PF03763.8 CAM68702.1 - 2.3 7.7 10.7 0.62 9.6 2.2 3.1 2 1 0 3 3 3 0 Remorin, C-terminal region TBPIP PF07106.8 CAM68702.1 - 9.1 5.7 13.4 6.6 6.2 1.0 2.4 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Pex2_Pex12 PF04757.9 CAM68703.1 - 1.1e-29 103.5 12.1 1.4e-29 103.1 8.4 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.20 CAM68703.1 - 0.017 14.7 12.1 0.027 14.1 8.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAM68703.1 - 0.024 14.6 11.0 0.047 13.7 7.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Sp100 PF03172.8 CAM68703.1 - 0.08 12.9 0.2 11 6.0 0.0 2.3 1 1 1 2 2 2 0 Sp100 domain zf-RING_5 PF14634.1 CAM68703.1 - 0.096 12.4 11.9 0.15 11.7 8.2 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CAM68703.1 - 0.15 11.9 10.8 0.27 11.1 7.5 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 CAM68703.1 - 2.2 8.0 13.3 3.3 7.4 9.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CAM68703.1 - 4.5 7.1 12.0 10 6.0 8.3 1.6 1 1 0 1 1 1 0 Ring finger domain PHD PF00628.24 CAM68704.1 - 7.2e-06 25.5 16.0 1.3e-05 24.7 5.4 2.6 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.1 CAM68704.1 - 0.013 14.7 5.5 0.031 13.5 0.5 2.4 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-C4_ClpX PF06689.8 CAM68704.1 - 0.078 12.5 1.4 0.3 10.6 1.0 2.0 1 1 0 1 1 1 0 ClpX C4-type zinc finger TMEM190 PF15431.1 CAM68707.1 - 0.12 12.3 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 190 zf-DHHC PF01529.15 CAM68709.1 - 6.9e-38 129.7 0.4 4e-37 127.2 0.0 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase Yip1 PF04893.12 CAM68709.1 - 0.031 13.7 0.1 0.031 13.7 0.1 2.2 2 0 0 2 2 2 0 Yip1 domain DUF1469 PF07332.6 CAM68709.1 - 0.2 11.3 0.1 0.2 11.3 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) Pex2_Pex12 PF04757.9 CAM68710.1 - 2.5e-14 53.2 0.0 2.6e-07 30.2 0.0 2.1 1 1 1 2 2 2 2 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 CAM68710.1 - 9.9e-09 34.9 11.4 1.6e-08 34.2 7.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CAM68710.1 - 1.8e-08 33.9 10.6 2.7e-08 33.3 7.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAM68710.1 - 3.4e-08 33.3 13.0 5.7e-08 32.6 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAM68710.1 - 9.4e-08 31.6 10.3 1.7e-07 30.8 7.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CAM68710.1 - 1.3e-06 27.9 12.5 2.2e-06 27.1 8.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CAM68710.1 - 4.8e-06 26.3 11.6 8.8e-06 25.4 8.1 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 CAM68710.1 - 8.5e-06 25.7 5.4 1.5e-05 25.0 3.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CAM68710.1 - 2.4e-05 24.0 6.0 4e-05 23.3 4.2 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 CAM68710.1 - 0.0052 16.4 4.9 0.014 15.0 3.2 1.9 1 1 1 2 2 2 1 RING-type zinc-finger TerY-C PF15616.1 CAM68710.1 - 0.014 15.3 3.3 0.022 14.6 2.3 1.2 1 0 0 1 1 1 0 TerY-C metal binding domain U-box PF04564.10 CAM68710.1 - 0.092 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 U-box domain zf-RING_6 PF14835.1 CAM68710.1 - 0.28 10.9 5.4 0.4 10.5 3.1 1.7 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-Di19 PF05605.7 CAM68710.1 - 0.31 11.2 0.1 0.31 11.2 0.1 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-Nse PF11789.3 CAM68710.1 - 0.43 10.1 5.0 0.99 8.9 3.5 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit IBR PF01485.16 CAM68710.1 - 1 9.2 10.4 0.21 11.4 4.2 2.0 1 1 1 2 2 2 0 IBR domain DZR PF12773.2 CAM68710.1 - 1.8 8.4 8.3 0.59 9.9 3.5 1.9 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_4 PF14570.1 CAM68710.1 - 2.1 8.0 10.6 5.4 6.6 7.3 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 CAM68710.1 - 4.3 6.9 9.8 29 4.2 6.8 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 LRR_4 PF12799.2 CAM68711.1 - 6.1e-12 44.8 5.0 8.8e-08 31.6 1.1 3.6 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM68711.1 - 9.5e-11 41.2 12.9 1.1e-06 28.2 1.8 2.5 2 1 1 3 3 3 2 Leucine rich repeat EF-hand_7 PF13499.1 CAM68711.1 - 9.4e-07 28.8 0.1 4.4e-06 26.7 0.0 2.3 1 0 0 1 1 1 1 EF-hand domain pair LRR_7 PF13504.1 CAM68711.1 - 0.00012 21.7 3.7 0.58 10.5 0.2 4.3 3 1 0 3 3 3 1 Leucine rich repeat EF-hand_1 PF00036.27 CAM68711.1 - 0.00017 20.6 0.0 0.0065 15.7 0.0 3.0 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 CAM68711.1 - 0.0013 18.2 0.1 0.25 10.9 0.0 3.0 1 1 1 2 2 2 1 EF-hand domain pair LRR_1 PF00560.28 CAM68711.1 - 0.0016 18.1 5.4 0.66 10.2 0.5 3.8 3 0 0 3 3 3 2 Leucine Rich Repeat EF-hand_6 PF13405.1 CAM68711.1 - 0.006 16.3 0.0 0.042 13.7 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain LRR_6 PF13516.1 CAM68711.1 - 0.01 15.8 2.3 0.79 9.9 0.1 3.1 2 1 1 3 3 3 0 Leucine Rich repeat Xpo1 PF08389.7 CAM68711.1 - 0.18 11.7 1.2 1.2 9.0 0.0 2.7 3 1 0 3 3 3 0 Exportin 1-like protein DUF4352 PF11611.3 CAM68712.1 - 0.0096 16.0 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4352) UPF0240 PF06784.6 CAM68712.1 - 0.081 12.5 0.2 0.33 10.6 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0240) SPC12 PF06645.8 CAM68713.1 - 6e-06 25.9 0.9 8.7e-06 25.4 0.6 1.2 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) COX14 PF14880.1 CAM68713.1 - 0.0029 17.1 0.0 0.0075 15.8 0.0 1.6 1 1 0 1 1 1 1 Cytochrome oxidase c assembly Col_cuticle_N PF01484.12 CAM68713.1 - 0.39 10.4 2.4 0.67 9.6 1.7 1.4 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain DUF4481 PF14800.1 CAM68713.1 - 0.76 8.6 2.9 0.98 8.2 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) VPS9 PF02204.13 CAM68714.1 - 2e-13 50.2 0.0 3e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain MORN PF02493.15 CAM68714.1 - 3.2e-09 35.9 20.0 6.7e-06 25.5 0.4 6.0 6 0 0 6 6 6 3 MORN repeat Cellulase-like PF12876.2 CAM68714.1 - 0.011 16.1 0.0 0.036 14.4 0.0 1.9 1 0 0 1 1 1 0 Sugar-binding cellulase-like Pkinase PF00069.20 CAM68715.1 - 3.9e-69 232.6 0.0 5.9e-69 232.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM68715.1 - 8.6e-39 133.1 0.0 1.2e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM68715.1 - 1.1e-06 27.7 0.0 1.9e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CAM68715.1 - 0.0086 15.8 0.0 0.27 10.9 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CAM68715.1 - 0.013 14.5 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ADIP PF11559.3 CAM68716.1 - 0.086 12.7 0.2 9.4 6.1 0.3 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding KN_motif PF12075.3 CAM68717.1 - 0.15 11.8 0.0 2.4 8.0 0.0 2.5 2 0 0 2 2 2 0 KN motif ADK PF00406.17 CAM68718.1 - 9.9e-37 126.1 0.0 1.2e-36 125.8 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 CAM68718.1 - 1.9e-18 65.8 3.3 2.9e-18 65.2 2.3 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 CAM68718.1 - 3.8e-06 27.7 0.0 6e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain A2L_zn_ribbon PF08792.5 CAM68718.1 - 0.0016 17.8 0.5 0.46 10.0 0.0 2.5 2 0 0 2 2 2 2 A2L zinc ribbon domain AAA_18 PF13238.1 CAM68718.1 - 0.0071 16.6 0.0 0.0096 16.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CAM68718.1 - 0.013 15.3 0.1 0.027 14.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain YadA_anchor PF03895.10 CAM68718.1 - 0.017 15.0 0.7 0.034 14.1 0.5 1.5 1 0 0 1 1 1 0 YadA-like C-terminal region RPEL PF02755.10 CAM68718.1 - 0.84 9.0 2.9 36 3.8 0.0 3.2 3 0 0 3 3 3 0 RPEL repeat zf-C2H2_3 PF13878.1 CAM68718.1 - 0.86 9.2 0.0 0.86 9.2 0.0 2.0 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO GSP_synth PF03738.9 CAM68719.1 - 1.2e-24 86.4 0.0 2.5e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 Glutathionylspermidine synthase preATP-grasp CHAP PF05257.11 CAM68719.1 - 6.5e-20 71.0 0.0 1.3e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 CHAP domain CP_ATPgrasp_2 PF14403.1 CAM68719.1 - 0.0054 15.4 0.0 0.0078 14.9 0.0 1.3 1 0 0 1 1 1 1 Circularly permuted ATP-grasp type 2 LSM PF01423.17 CAM68720.1 - 4.4e-12 45.3 0.2 5.9e-12 44.9 0.1 1.2 1 0 0 1 1 1 1 LSM domain Brix PF04427.13 CAM68721.1 - 4.9e-37 127.4 0.0 1e-36 126.4 0.0 1.5 2 0 0 2 2 2 1 Brix domain Glyoxalase_4 PF13669.1 CAM68722.1 - 8.6e-16 57.9 0.0 1.1e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 CAM68722.1 - 0.00037 21.0 0.0 0.00052 20.5 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 CAM68722.1 - 0.00049 20.0 0.0 0.00059 19.8 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 CAM68722.1 - 0.00058 19.8 0.0 0.00069 19.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain GDC-P PF02347.11 CAM68723.1 - 3.6e-174 579.4 0.1 4.8e-158 526.3 0.1 3.1 3 0 0 3 3 3 3 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 CAM68723.1 - 0.0003 20.0 0.1 0.0018 17.4 0.0 2.0 2 0 0 2 2 2 1 Beta-eliminating lyase DUF4473 PF14747.1 CAM68723.1 - 0.16 12.1 0.0 0.47 10.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) Pkinase PF00069.20 CAM68724.1 - 1.4e-54 185.0 0.0 1.6e-54 184.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM68724.1 - 4.1e-22 78.4 0.0 4.6e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM68724.1 - 0.00028 19.9 0.0 0.00088 18.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Synthase_beta PF11421.3 CAM68726.1 - 0.65 10.7 7.4 0.35 11.5 0.7 2.9 2 0 0 2 2 2 0 ATP synthase F1 beta subunit Rhomboid PF01694.17 CAM68731.1 - 0.0036 17.3 1.3 0.0085 16.1 0.2 1.9 2 0 0 2 2 2 1 Rhomboid family MauE PF07291.6 CAM68731.1 - 0.14 11.8 1.4 0.17 11.5 0.2 1.8 2 0 0 2 2 2 0 Methylamine utilisation protein MauE Pribosyltran PF00156.22 CAM68732.1 - 3.4e-16 59.0 0.0 5.2e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CAM68732.1 - 5.5e-05 22.4 0.0 7.1e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 CAM68732.1 - 0.003 16.9 0.1 0.0055 16.0 0.0 1.7 2 1 0 2 2 2 1 Phosphoribosyl transferase Racemase_4 PF13615.1 CAM68733.1 - 4.3e-21 75.0 0.2 1.2e-20 73.6 0.1 1.8 1 0 0 1 1 1 1 Putative alanine racemase MCM_bind PF09739.4 CAM68733.1 - 4.4e-14 52.0 0.0 8e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor NIF PF03031.13 CAM68734.1 - 2.6e-49 166.9 0.2 4.4e-49 166.1 0.2 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Ribosomal_L30 PF00327.15 CAM68735.1 - 1.1e-18 66.5 1.2 2.1e-18 65.6 0.8 1.6 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.7 CAM68735.1 - 6.4e-16 58.1 13.8 1.3e-15 57.1 9.6 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain DUF1453 PF07301.6 CAM68737.1 - 0.35 10.7 4.3 2 8.2 0.5 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1453) Nfu_N PF08712.6 CAM68738.1 - 2.4e-24 84.7 0.0 4e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 CAM68738.1 - 2.1e-21 75.4 0.4 7.6e-21 73.6 0.0 2.0 2 0 0 2 2 2 1 NifU-like domain eRF1_1 PF03463.10 CAM68739.1 - 1.5e-31 108.7 0.0 2.9e-31 107.7 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 CAM68739.1 - 8.2e-19 68.2 0.1 1.4e-18 67.4 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 CAM68739.1 - 1.9e-14 53.8 0.0 6.1e-14 52.2 0.0 1.9 2 0 0 2 2 2 1 eRF1 domain 3 DUF334 PF03904.8 CAM68739.1 - 0.02 14.2 0.2 0.032 13.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF334) SIR2 PF02146.12 CAM68740.1 - 2.9e-58 196.5 0.0 3.7e-58 196.1 0.0 1.1 1 0 0 1 1 1 1 Sir2 family zinc_ribbon_4 PF13717.1 CAM68740.1 - 0.022 14.4 1.6 0.059 13.0 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CAM68740.1 - 0.037 13.6 1.6 0.08 12.5 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain DUF2305 PF10230.4 CAM68741.1 - 3e-62 210.4 0.0 3.5e-62 210.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 CAM68741.1 - 1.2e-13 51.5 0.1 1.5e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CAM68741.1 - 3.3e-11 43.1 0.0 5.3e-11 42.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 CAM68741.1 - 0.0011 18.6 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.3 CAM68741.1 - 0.0043 16.8 0.0 0.0074 16.1 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 CAM68741.1 - 0.048 13.8 0.0 0.087 13.0 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_1 PF00561.15 CAM68741.1 - 0.051 13.1 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1057 PF06342.7 CAM68741.1 - 0.079 11.7 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) DUF2974 PF11187.3 CAM68741.1 - 0.14 11.5 0.1 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Rootletin PF15035.1 CAM68742.1 - 0.11 12.5 1.9 0.2 11.6 0.3 2.0 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion IF4E PF01652.13 CAM68743.1 - 8.3e-12 44.9 0.0 1e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E MMR_HSR1 PF01926.18 CAM68746.1 - 3.3e-42 143.1 0.1 4.1e-20 71.8 0.0 2.6 3 0 0 3 3 3 2 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CAM68746.1 - 1.2e-26 93.3 0.4 3.2e-13 49.5 0.0 3.7 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CAM68746.1 - 3.3e-21 75.1 0.1 8.4e-10 38.1 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B Miro PF08477.8 CAM68746.1 - 4.5e-19 69.1 0.0 3.4e-08 34.0 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein Dynamin_N PF00350.18 CAM68746.1 - 1.1e-17 64.4 0.0 0.00099 18.9 0.0 4.4 3 1 1 4 4 4 3 Dynamin family AIG1 PF04548.11 CAM68746.1 - 5.9e-15 54.9 0.2 1.4e-06 27.5 0.0 2.8 3 1 0 3 3 2 2 AIG1 family KH_dom-like PF14714.1 CAM68746.1 - 9e-15 54.4 0.3 1.8e-14 53.4 0.2 1.6 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal SRPRB PF09439.5 CAM68746.1 - 1.7e-11 43.6 0.0 7.9e-05 21.9 0.0 2.4 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit Ras PF00071.17 CAM68746.1 - 6.2e-11 41.9 0.0 8.3e-07 28.5 0.1 2.7 2 1 0 2 2 2 2 Ras family PduV-EutP PF10662.4 CAM68746.1 - 1.8e-06 27.5 0.0 0.21 11.0 0.0 3.6 2 2 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 CAM68746.1 - 2e-06 27.5 0.0 0.011 15.3 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 CAM68746.1 - 7.1e-06 25.2 0.0 0.098 11.8 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Septin PF00735.13 CAM68746.1 - 1.2e-05 24.4 0.0 0.0093 15.0 0.0 2.4 2 0 0 2 2 2 2 Septin ABC_tran PF00005.22 CAM68746.1 - 1.2e-05 25.6 0.0 0.21 11.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter Arf PF00025.16 CAM68746.1 - 2.8e-05 23.4 0.5 0.05 12.8 0.1 3.3 2 2 0 2 2 2 1 ADP-ribosylation factor family AAA_18 PF13238.1 CAM68746.1 - 3.9e-05 23.9 0.1 0.065 13.5 0.0 2.8 3 0 0 3 3 2 2 AAA domain GBP PF02263.14 CAM68746.1 - 4.9e-05 22.5 0.0 0.24 10.4 0.0 2.3 2 0 0 2 2 2 2 Guanylate-binding protein, N-terminal domain cobW PF02492.14 CAM68746.1 - 6.7e-05 22.4 1.3 0.25 10.7 0.3 3.9 3 1 1 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain IIGP PF05049.8 CAM68746.1 - 0.00017 20.5 0.0 0.031 13.1 0.0 2.4 2 1 0 2 2 2 1 Interferon-inducible GTPase (IIGP) ATP_bind_1 PF03029.12 CAM68746.1 - 0.00055 19.5 1.4 2.3 7.7 0.0 3.8 2 2 2 4 4 4 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 CAM68746.1 - 0.00058 20.6 0.9 2.7 8.8 0.1 3.6 2 2 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 CAM68746.1 - 0.0024 17.6 0.0 0.45 10.1 0.0 2.7 2 0 0 2 2 2 1 Archaeal ATPase T2SE PF00437.15 CAM68746.1 - 0.0026 16.7 0.0 0.01 14.7 0.0 2.0 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_10 PF12846.2 CAM68746.1 - 0.0046 16.4 0.0 2.6 7.4 0.0 2.6 2 1 0 2 2 2 2 AAA-like domain AAA_29 PF13555.1 CAM68746.1 - 0.0077 15.7 0.0 3.8 7.1 0.0 2.8 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CAM68746.1 - 0.015 15.4 0.0 2.3 8.3 0.0 3.2 3 1 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.13 CAM68746.1 - 0.035 13.5 0.0 2.4 7.5 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.1 CAM68746.1 - 0.05 13.9 0.0 23 5.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_21 PF13304.1 CAM68746.1 - 0.14 12.0 0.1 2.2 8.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain MethyTransf_Reg PF10119.4 CAM68747.1 - 0.032 14.7 0.0 0.47 10.9 0.0 2.5 2 1 0 2 2 2 0 Predicted methyltransferase regulatory domain NUDIX_2 PF13869.1 CAM68748.1 - 2.4e-42 144.3 0.0 4.7e-41 140.1 0.0 2.6 1 1 0 1 1 1 1 Nucleotide hydrolase NUDIX PF00293.23 CAM68748.1 - 0.028 14.0 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 NUDIX domain 6PF2K PF01591.13 CAM68750.1 - 5.3e-32 110.6 0.0 8.1e-32 110.0 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase Ank_2 PF12796.2 CAM68750.1 - 6.2e-23 80.9 0.0 1.6e-12 47.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) His_Phos_1 PF00300.17 CAM68750.1 - 5e-16 59.1 0.0 1.4e-15 57.6 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Ank_5 PF13857.1 CAM68750.1 - 1.6e-13 50.4 0.1 3.7e-13 49.2 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 CAM68750.1 - 1.5e-12 46.6 0.2 5.3e-08 32.2 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 CAM68750.1 - 7.4e-12 45.4 0.1 1.5e-07 31.7 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CAM68750.1 - 1.1e-07 31.3 0.1 2.9e-06 27.0 0.0 3.2 4 0 0 4 4 2 1 Ankyrin repeat AAA_33 PF13671.1 CAM68750.1 - 3.2e-07 30.3 0.2 5.9e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 CAM68750.1 - 7.6e-05 22.0 0.1 0.00015 21.1 0.1 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 CAM68750.1 - 0.00078 18.5 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 CAM68750.1 - 0.02 15.6 0.0 0.045 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CAM68750.1 - 0.026 14.2 0.1 0.091 12.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CAM68750.1 - 0.086 12.9 0.1 0.73 9.9 0.0 2.2 1 1 1 2 2 2 0 AAA domain APS_kinase PF01583.15 CAM68750.1 - 0.13 11.9 0.0 0.51 9.9 0.0 1.9 2 1 0 3 3 3 0 Adenylylsulphate kinase THF_DHG_CYH_C PF02882.14 CAM68751.1 - 4.2e-62 207.9 0.2 6e-62 207.4 0.1 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 CAM68751.1 - 1e-38 131.9 0.5 1.4e-38 131.4 0.3 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.10 CAM68751.1 - 0.045 12.5 0.1 0.065 11.9 0.1 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Cyclin_N PF00134.18 CAM68752.1 - 5.3e-14 51.8 0.4 2.5e-13 49.6 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain DUF2637 PF10935.3 CAM68752.1 - 0.0095 15.8 0.5 0.23 11.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2637) Cyclin_C PF02984.14 CAM68752.1 - 0.06 13.2 2.0 0.14 12.1 0.4 2.2 1 1 1 2 2 2 0 Cyclin, C-terminal domain IU_nuc_hydro PF01156.14 CAM68753.1 - 1.8e-29 103.0 2.0 9.9e-27 93.9 0.6 2.0 1 1 1 2 2 2 2 Inosine-uridine preferring nucleoside hydrolase MIG-14_Wnt-bd PF06664.7 CAM68753.1 - 0.0082 14.9 0.3 0.011 14.6 0.2 1.2 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion Vps52 PF04129.7 CAM68754.1 - 2.6e-48 164.8 0.0 8e-17 60.9 0.0 3.6 3 1 0 3 3 3 3 Vps52 / Sac2 family DASH_Duo1 PF08651.5 CAM68754.1 - 0.0073 15.8 0.1 0.28 10.8 0.1 2.5 2 0 0 2 2 2 1 DASH complex subunit Duo1 Sec3_C PF09763.4 CAM68754.1 - 0.066 11.3 1.6 1.4 6.9 0.0 2.8 3 0 0 3 3 3 0 Exocyst complex component Sec3 TPR_11 PF13414.1 CAM68756.1 - 4.5e-38 128.7 24.9 1.9e-06 27.3 0.0 10.3 8 1 1 10 10 10 8 TPR repeat TPR_2 PF07719.12 CAM68756.1 - 6e-29 97.6 40.0 0.00097 18.8 0.0 15.1 16 0 0 16 16 15 7 Tetratricopeptide repeat TPR_12 PF13424.1 CAM68756.1 - 2.9e-24 84.8 41.4 2.6e-05 24.0 1.1 11.6 8 1 3 11 11 11 8 Tetratricopeptide repeat TPR_1 PF00515.23 CAM68756.1 - 2.7e-23 80.5 24.6 0.00035 20.0 0.0 12.1 14 0 0 14 14 13 5 Tetratricopeptide repeat TPR_8 PF13181.1 CAM68756.1 - 1.4e-18 65.2 10.4 0.0013 18.3 0.0 11.7 16 0 0 16 16 14 4 Tetratricopeptide repeat TPR_9 PF13371.1 CAM68756.1 - 8.2e-15 54.4 53.6 0.047 13.5 0.7 11.3 6 2 5 11 11 11 8 Tetratricopeptide repeat TPR_16 PF13432.1 CAM68756.1 - 2.3e-13 50.4 60.5 0.018 15.7 3.4 11.5 7 2 5 12 12 12 7 Tetratricopeptide repeat TPR_19 PF14559.1 CAM68756.1 - 3.7e-09 36.7 26.6 0.014 15.7 0.0 8.6 8 2 1 9 9 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 CAM68756.1 - 2.9e-07 30.5 58.3 0.061 13.9 0.0 12.9 10 3 4 14 14 14 4 Tetratricopeptide repeat Apc3 PF12895.2 CAM68756.1 - 7.7e-07 29.1 19.1 0.4 10.8 0.0 7.2 3 2 4 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 CAM68756.1 - 1.3e-05 25.0 15.7 4 7.8 0.0 9.5 10 0 0 10 10 10 1 Tetratricopeptide repeat NARP1 PF12569.3 CAM68756.1 - 0.00017 20.4 2.7 0.91 8.1 0.0 4.6 5 0 0 5 5 5 1 NMDA receptor-regulated protein 1 Apc5 PF12862.2 CAM68756.1 - 0.0021 17.8 11.1 2.6 7.9 0.0 6.2 5 2 1 6 6 6 1 Anaphase-promoting complex subunit 5 Fis1_TPR_C PF14853.1 CAM68756.1 - 0.025 14.4 6.1 0.63 9.9 0.0 4.8 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat SHNi-TPR PF10516.4 CAM68756.1 - 0.06 12.6 2.1 0.95 8.7 0.0 3.9 4 0 0 4 4 4 0 SHNi-TPR TPR_6 PF13174.1 CAM68756.1 - 0.07 13.6 34.2 17 6.1 0.0 11.4 14 0 0 14 14 11 0 Tetratricopeptide repeat Ist1 PF03398.9 CAM68757.1 - 1.4e-59 200.1 0.3 1.7e-59 199.8 0.2 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway PAP_assoc PF03828.14 CAM68758.1 - 8.7e-15 54.4 0.2 2e-14 53.2 0.1 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 CAM68758.1 - 5e-06 26.7 0.0 1.3e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain 2OG-FeII_Oxy_2 PF13532.1 CAM68759.1 - 2.2e-13 50.4 0.0 3.9e-13 49.6 0.0 1.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 CAM68759.1 - 1.1e-06 28.8 0.0 2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-trcl PF13451.1 CAM68760.1 - 0.028 14.0 1.9 0.028 14.0 1.3 2.5 2 0 0 2 2 2 0 Probable zinc-binding domain zf-RING_4 PF14570.1 CAM68760.1 - 0.047 13.2 0.5 0.047 13.2 0.4 3.0 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF1091 PF06477.8 CAM68760.1 - 0.051 14.0 0.0 0.068 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1091) zf-H2C2_2 PF13465.1 CAM68760.1 - 0.11 12.7 0.5 0.11 12.7 0.4 3.3 2 1 0 2 2 2 0 Zinc-finger double domain zf-4CXXC_R1 PF10497.4 CAM68760.1 - 0.15 12.2 9.2 0.39 10.8 6.3 1.6 1 1 1 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 DUF3090 PF11290.3 CAM68760.1 - 0.17 11.3 0.5 0.5 9.8 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3090) zf-C3HC4_3 PF13920.1 CAM68760.1 - 2.9 7.6 13.2 6.1 6.6 0.1 3.1 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.19 CAM68760.1 - 6.8 6.6 16.2 1e+02 2.9 8.9 3.0 2 1 0 2 2 2 0 B-box zinc finger PyrI_C PF02748.10 CAM68760.1 - 7.9 6.0 12.4 5.9 6.4 0.0 3.2 1 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Cys_rich_KTR PF14205.1 CAM68760.1 - 8.8 5.8 10.8 13 5.3 0.0 2.7 2 1 1 3 3 3 0 Cysteine-rich KTR PseudoU_synth_1 PF01416.15 CAM68761.1 - 9.3e-13 48.5 0.0 9e-08 32.5 0.0 3.3 2 1 0 2 2 2 2 tRNA pseudouridine synthase ParA PF10609.4 CAM68762.1 - 4.2e-36 122.6 0.1 7.8e-36 121.8 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 CAM68762.1 - 6e-16 58.4 0.0 9.6e-16 57.7 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 CAM68762.1 - 1.9e-08 33.7 0.2 3.9e-06 26.1 0.1 2.8 3 0 0 3 3 3 1 Anion-transporting ATPase AAA_31 PF13614.1 CAM68762.1 - 7e-07 29.3 0.0 4.3e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 CAM68762.1 - 2.5e-06 26.7 0.0 0.00019 20.6 0.0 2.1 2 0 0 2 2 2 1 ATPase MipZ AAA_25 PF13481.1 CAM68762.1 - 0.00012 21.5 0.4 0.00033 20.0 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CAM68762.1 - 0.00077 19.1 0.4 0.17 11.6 0.7 2.6 2 0 0 2 2 2 1 Part of AAA domain Fer4_NifH PF00142.13 CAM68762.1 - 0.0019 17.4 0.0 0.005 16.0 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NACHT PF05729.7 CAM68762.1 - 0.013 15.2 0.3 0.025 14.2 0.2 1.4 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.1 CAM68762.1 - 0.042 14.6 0.1 0.09 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 CAM68762.1 - 0.047 13.3 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase zf-C4_ClpX PF06689.8 CAM68762.1 - 0.077 12.5 2.2 0.15 11.6 1.5 1.4 1 0 0 1 1 1 0 ClpX C4-type zinc finger DUF258 PF03193.11 CAM68762.1 - 0.091 11.9 0.2 0.19 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Hpr_kinase_C PF07475.7 CAM68762.1 - 0.096 11.9 0.2 0.31 10.3 0.1 1.8 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_22 PF13401.1 CAM68762.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CAM68762.1 - 0.13 12.4 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 CAM68762.1 - 0.18 10.6 0.1 0.3 9.9 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain IstB_IS21 PF01695.12 CAM68762.1 - 0.18 11.2 0.2 0.37 10.1 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF1358 PF07096.6 CAM68763.1 - 0.0028 17.3 0.1 0.0061 16.2 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1358) DUF2474 PF10617.4 CAM68766.1 - 0.006 16.1 0.4 0.017 14.6 0.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2474) ATP_bind_1 PF03029.12 CAM68767.1 - 3.1e-48 164.3 0.0 4.8e-47 160.4 0.0 2.0 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 CAM68767.1 - 0.0057 17.4 2.3 0.017 15.9 0.2 2.4 2 2 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CAM68767.1 - 0.0097 15.7 0.6 0.02 14.7 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CAM68767.1 - 0.019 15.2 1.3 0.16 12.2 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 CAM68767.1 - 0.02 15.0 0.2 0.14 12.2 0.0 2.4 2 2 1 3 3 3 0 AAA domain AAA PF00004.24 CAM68767.1 - 0.054 13.6 0.0 0.39 10.9 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 CAM68767.1 - 0.075 12.7 0.2 0.6 9.9 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain PAP_assoc PF03828.14 CAM68768.1 - 3e-08 33.4 0.0 6.4e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase LRR_6 PF13516.1 CAM68769.1 - 4.3e-26 88.0 16.1 0.28 11.3 0.0 12.5 12 0 0 12 12 12 9 Leucine Rich repeat LRR_4 PF12799.2 CAM68769.1 - 5.6e-10 38.6 12.6 0.047 13.3 0.1 6.4 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 CAM68769.1 - 2.9e-09 35.6 13.6 5.4 7.6 0.0 10.0 10 0 0 10 10 10 2 Leucine rich repeat LRR_1 PF00560.28 CAM68769.1 - 1.1e-07 30.8 15.4 0.91 9.7 0.1 9.7 10 2 1 11 11 11 2 Leucine Rich Repeat LRR_8 PF13855.1 CAM68769.1 - 1.2e-05 24.9 14.8 0.23 11.2 0.1 6.1 4 3 1 5 5 5 4 Leucine rich repeat HrcA_DNA-bdg PF03444.10 CAM68769.1 - 0.17 11.3 1.1 1.7 8.0 0.0 3.1 3 1 0 4 4 4 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Glycos_transf_2 PF00535.21 CAM68772.1 - 0.0088 15.7 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 MAPKK1_Int PF08923.5 CAM68774.1 - 0.0014 18.2 0.0 0.047 13.3 0.0 2.0 2 0 0 2 2 2 2 Mitogen-activated protein kinase kinase 1 interacting DUF525 PF04379.9 CAM68775.1 - 4.6e-18 64.9 0.0 1.1e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF525) DUF3138 PF11336.3 CAM68776.1 - 0.66 8.0 4.9 3.9 5.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Taxilin PF09728.4 CAM68777.1 - 6.6e-05 22.1 51.7 8.8e-05 21.7 33.9 2.2 1 1 1 2 2 2 1 Myosin-like coiled-coil protein AAA_13 PF13166.1 CAM68777.1 - 0.00041 18.9 14.0 0.00041 18.9 9.7 2.1 1 1 1 2 2 2 1 AAA domain BRE1 PF08647.6 CAM68777.1 - 0.0018 18.1 6.1 0.0018 18.1 4.2 4.4 1 1 3 4 4 4 1 BRE1 E3 ubiquitin ligase IMS PF00817.15 CAM68777.1 - 0.0098 15.7 0.4 0.0098 15.7 0.3 2.6 2 1 0 2 2 2 1 impB/mucB/samB family Reo_sigmaC PF04582.7 CAM68777.1 - 0.05 12.7 5.0 0.39 9.8 0.1 2.6 1 1 0 2 2 2 0 Reovirus sigma C capsid protein Fib_alpha PF08702.5 CAM68777.1 - 0.11 12.5 28.2 0.14 12.2 7.4 3.0 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.2 CAM68777.1 - 0.37 10.6 51.6 0.15 11.9 11.3 4.1 1 1 1 3 3 3 0 Tropomyosin like Filament PF00038.16 CAM68777.1 - 1.1 8.6 48.9 28 4.0 19.3 3.6 1 1 1 2 2 2 0 Intermediate filament protein Tet_JBP PF12851.2 CAM68777.1 - 1.4 8.2 3.7 0.56 9.4 0.1 2.2 2 0 0 2 2 2 0 Oxygenase domain of the 2OGFeDO superfamily TroA PF01297.12 CAM68777.1 - 1.6 7.9 7.6 0.82 8.8 0.1 2.8 1 1 1 2 2 2 0 Periplasmic solute binding protein family IncA PF04156.9 CAM68777.1 - 5.5 6.5 53.0 0.14 11.7 9.8 4.0 1 1 2 3 3 3 0 IncA protein PPR_2 PF13041.1 CAM68778.1 - 1.6e-14 53.5 3.4 5.2e-07 29.5 0.0 3.9 2 2 2 4 4 4 4 PPR repeat family PPR_3 PF13812.1 CAM68778.1 - 4.1e-10 39.1 4.1 6.3e-05 22.9 0.1 4.8 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.15 CAM68778.1 - 7.3e-07 28.7 10.2 0.004 17.0 0.1 5.2 5 1 0 5 5 5 2 PPR repeat Propeptide_C1 PF08127.8 CAM68778.1 - 0.023 14.2 0.1 0.044 13.4 0.1 1.4 1 0 0 1 1 1 0 Peptidase family C1 propeptide MNE1 PF13762.1 CAM68778.1 - 0.07 13.1 0.1 0.87 9.6 0.0 2.3 1 1 0 2 2 2 0 Mitochondrial splicing apparatus component Med3 PF11593.3 CAM68778.1 - 1.2 8.2 5.9 1.7 7.8 4.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Cpn10 PF00166.16 CAM68779.1 - 2.8e-23 81.6 0.3 3.1e-23 81.5 0.2 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cpn10 PF00166.16 CAM68781.1 - 2.8e-23 81.6 0.3 3.1e-23 81.5 0.2 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Pyr_redox_3 PF13738.1 CAM68782.1 - 0.029 14.4 0.0 5.3 7.0 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thioredoxin PF00085.15 CAM68783.1 - 6.8e-58 192.7 0.0 3.6e-28 97.3 0.1 2.2 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 CAM68783.1 - 4.5e-21 75.2 0.1 1e-20 74.1 0.1 1.6 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 CAM68783.1 - 1.7e-18 66.8 0.2 1.8e-07 31.3 0.0 3.4 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CAM68783.1 - 4.5e-12 45.9 0.1 1.9e-05 24.6 0.1 4.0 2 2 2 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.1 CAM68783.1 - 3e-11 43.1 0.2 3.8e-06 26.8 0.0 2.7 2 1 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.16 CAM68783.1 - 4.2e-08 32.9 0.1 0.0019 17.8 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 CAM68783.1 - 1.5e-06 27.8 0.1 0.0045 16.5 0.0 2.4 2 0 0 2 2 2 2 Redoxin Thioredoxin_6 PF13848.1 CAM68783.1 - 6e-05 22.9 0.0 0.045 13.5 0.1 3.2 2 1 0 3 3 3 1 Thioredoxin-like domain TraF PF13728.1 CAM68783.1 - 0.00014 21.4 0.0 0.48 9.8 0.0 2.5 2 0 0 2 2 2 2 F plasmid transfer operon protein HyaE PF07449.6 CAM68783.1 - 0.00039 20.2 0.0 1.5 8.7 0.0 2.7 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Thioredoxin_5 PF13743.1 CAM68783.1 - 0.0085 15.6 0.0 2 7.9 0.0 3.5 2 2 2 4 4 4 1 Thioredoxin Thioredoxin_9 PF14595.1 CAM68783.1 - 0.015 14.8 0.1 0.38 10.3 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_4 PF13462.1 CAM68783.1 - 0.02 14.9 2.3 5.3 7.0 0.1 3.0 4 0 0 4 4 4 0 Thioredoxin Glutaredoxin PF00462.19 CAM68783.1 - 0.037 14.0 1.5 0.59 10.1 0.0 2.8 2 1 0 2 2 2 0 Glutaredoxin Thioredoxin PF00085.15 CAM68784.1 - 1.2e-06 28.1 0.0 1.4e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CAM68784.1 - 0.048 13.8 0.0 0.058 13.6 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain DUF2012 PF09430.5 CAM68785.1 - 3.9e-33 113.9 0.1 5.1e-33 113.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.1 CAM68785.1 - 0.0012 18.8 0.1 0.0036 17.3 0.0 1.8 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain COX4 PF02936.9 CAM68785.1 - 0.11 12.2 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV SNARE PF05739.14 CAM68786.1 - 1.4e-08 34.2 3.9 1.4e-08 34.2 2.7 2.2 3 0 0 3 3 3 1 SNARE domain Syntaxin-6_N PF09177.6 CAM68786.1 - 2.7e-06 27.6 0.3 9.4e-05 22.7 0.0 2.4 2 1 0 2 2 2 1 Syntaxin 6, N-terminal CALCOCO1 PF07888.6 CAM68786.1 - 6e-05 21.5 6.6 7.1e-05 21.2 4.6 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like CRPA PF05745.6 CAM68786.1 - 0.079 12.7 0.2 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) DivIVA PF05103.8 CAM68786.1 - 0.3 11.1 4.6 0.36 10.8 0.7 2.3 2 0 0 2 2 2 0 DivIVA protein Laminin_II PF06009.7 CAM68786.1 - 0.39 10.4 2.9 0.44 10.2 0.3 2.1 2 1 0 2 2 2 0 Laminin Domain II EMP24_GP25L PF01105.19 CAM68786.1 - 0.73 9.5 4.8 0.11 12.1 0.4 1.7 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF2951 PF11166.3 CAM68786.1 - 1.2 9.0 5.0 0.2 11.5 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Pentapeptide_4 PF13599.1 CAM68787.1 - 4.6e-08 32.7 5.0 5.4e-07 29.3 0.5 3.1 2 1 1 3 3 3 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 CAM68787.1 - 1.4e-05 24.9 10.3 0.00022 21.0 0.0 4.1 2 1 2 4 4 4 3 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 CAM68787.1 - 3e-05 23.1 1.7 0.00051 19.2 0.0 3.5 2 1 1 3 3 3 1 Pentapeptide repeats (8 copies) DAGK_cat PF00781.19 CAM68788.1 - 2.3e-11 43.2 0.1 2.2e-10 40.0 0.0 2.5 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain zf-RING_UBOX PF13445.1 CAM68790.2 - 0.017 14.8 0.0 0.06 13.0 0.0 1.9 1 0 0 1 1 1 0 RING-type zinc-finger RCC1 PF00415.13 CAM68791.1 - 1.1e-72 239.9 42.0 1e-14 54.4 0.4 12.4 11 2 0 11 11 11 11 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CAM68791.1 - 3.6e-40 134.7 77.1 3.2e-07 29.7 0.9 12.1 13 0 0 13 13 13 10 Regulator of chromosome condensation (RCC1) repeat GAD-like PF08887.6 CAM68791.1 - 0.023 14.7 0.3 24 5.0 0.0 4.0 4 0 0 4 4 4 0 GAD-like domain CBM_X PF06204.6 CAM68791.1 - 0.3 10.5 10.5 37 3.9 0.0 5.4 5 0 0 5 5 5 0 Putative carbohydrate binding domain Peptidase_C25_C PF03785.9 CAM68791.1 - 9.7 6.0 6.5 43 4.0 0.0 4.5 5 1 1 6 6 6 0 Peptidase family C25, C terminal ig-like domain RRM_1 PF00076.17 CAM68793.1 - 3.1e-11 42.7 0.1 4.7e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM68793.1 - 3.2e-09 36.6 0.0 5e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM68793.1 - 0.00096 18.9 0.1 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAM68795.1 - 1.9e-08 33.8 0.1 2.6e-07 30.1 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM68795.1 - 5.3e-08 32.7 0.0 8.3e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM68795.1 - 0.00011 21.9 0.0 0.00018 21.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GSHPx PF00255.14 CAM68797.1 - 4.2e-38 129.0 0.2 5.3e-38 128.7 0.2 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 CAM68797.1 - 0.0019 17.8 0.1 0.0036 16.9 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 CAM68797.1 - 0.069 12.6 0.0 0.093 12.2 0.0 1.5 1 1 0 1 1 1 0 Redoxin GSHPx PF00255.14 CAM68798.1 - 3.6e-38 129.2 0.2 4.6e-38 128.9 0.2 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 CAM68798.1 - 0.0022 17.6 0.1 0.0042 16.7 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 CAM68798.1 - 0.11 12.0 0.0 0.14 11.6 0.0 1.5 1 1 0 1 1 1 0 Redoxin AsnA PF03590.10 CAM68799.1 - 4.5e-93 311.1 0.0 1.3e-90 303.1 0.0 2.1 1 1 0 1 1 1 1 Aspartate-ammonia ligase tRNA-synt_2 PF00152.15 CAM68799.1 - 0.00011 21.1 0.0 0.067 11.9 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) Nuc-transf PF10127.4 CAM68801.1 - 0.013 14.8 0.1 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Predicted nucleotidyltransferase IF3_C PF00707.17 CAM68801.1 - 0.094 12.4 0.3 0.28 10.9 0.1 1.9 2 0 0 2 2 2 0 Translation initiation factor IF-3, C-terminal domain Exo_endo_phos PF03372.18 CAM68802.1 - 6e-11 42.7 0.0 9.6e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family XRN_N PF03159.13 CAM68802.1 - 0.065 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus FYRC PF05965.9 CAM68803.1 - 0.00014 21.6 0.0 0.00028 20.6 0.0 1.5 1 0 0 1 1 1 1 F/Y rich C-terminus DUF3665 PF12427.3 CAM68803.1 - 0.14 11.5 1.7 0.72 9.2 1.2 2.3 1 0 0 1 1 1 0 Branched-chain amino acid aminotransferase Ribosomal_S9 PF00380.14 CAM68804.1 - 1.9e-29 102.3 0.9 2.2e-29 102.1 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 HSP70 PF00012.15 CAM68806.2 - 9.1e-78 261.6 0.0 2.3e-41 141.4 0.0 2.4 3 0 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.8 CAM68806.2 - 0.00023 19.9 0.1 0.15 10.6 0.0 3.2 2 1 1 3 3 3 2 MreB/Mbl protein FtsA PF14450.1 CAM68806.2 - 0.013 15.3 0.5 30 4.4 0.0 3.8 4 0 0 4 4 4 0 Cell division protein FtsA FGGY_C PF02782.11 CAM68806.2 - 0.023 14.3 0.0 0.047 13.3 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.6 CAM68806.2 - 0.088 11.7 0.0 0.24 10.2 0.0 1.7 1 0 0 1 1 1 0 StbA protein OGFr_N PF04664.8 CAM68807.1 - 6.4e-05 22.3 0.1 0.019 14.2 0.0 2.3 2 0 0 2 2 2 2 Opioid growth factor receptor (OGFr) conserved region DUF2517 PF10725.4 CAM68808.1 - 0.16 11.7 0.6 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2517) PIF1 PF05970.9 CAM68809.1 - 1.1e-05 24.5 0.0 2.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase IstB_IS21 PF01695.12 CAM68809.1 - 6.3e-05 22.4 0.3 0.00094 18.6 0.1 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein SRP54 PF00448.17 CAM68809.1 - 0.005 16.3 0.1 0.011 15.2 0.0 1.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain DUF815 PF05673.8 CAM68809.1 - 0.025 13.5 0.0 0.044 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Bac_DnaA PF00308.13 CAM68809.1 - 0.036 13.7 0.3 0.074 12.6 0.0 1.6 2 0 0 2 2 2 0 Bacterial dnaA protein DZR PF12773.2 CAM68809.1 - 0.058 13.2 2.1 6.4 6.6 1.7 2.6 1 1 1 2 2 2 0 Double zinc ribbon DUF3395 PF11875.3 CAM68810.1 - 8.7e-50 168.2 0.0 1.5e-49 167.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 CAM68810.1 - 3.3e-14 52.3 0.2 6.1e-14 51.5 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain DUF605 PF04652.11 CAM68810.1 - 0.35 10.2 11.6 0.49 9.7 8.1 1.2 1 0 0 1 1 1 0 Vta1 like Mcp5_PH PF12814.2 CAM68811.1 - 1.2e-24 86.6 1.0 1.9e-24 85.9 0.7 1.3 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology NMD3 PF04981.8 CAM68813.1 - 4.6e-75 251.7 4.1 6.2e-75 251.3 2.9 1.2 1 0 0 1 1 1 1 NMD3 family DZR PF12773.2 CAM68813.1 - 1.5 8.6 10.5 0.47 10.3 1.8 2.8 2 1 0 2 2 2 0 Double zinc ribbon TF_Zn_Ribbon PF08271.7 CAM68813.1 - 9.9 5.5 11.0 1.6 8.0 1.8 3.2 2 1 0 2 2 2 0 TFIIB zinc-binding Pkinase PF00069.20 CAM68814.1 - 1.1e-33 116.4 0.0 2.9e-33 115.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM68814.1 - 3.9e-12 45.8 0.0 3.1e-06 26.4 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CAM68814.1 - 0.006 15.4 0.1 0.0089 14.8 0.1 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase PKD_channel PF08016.7 CAM68815.1 - 1.7e-07 30.0 9.9 2.9e-07 29.2 6.9 1.3 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 CAM68815.1 - 0.00013 21.2 12.4 0.00013 21.2 8.6 2.3 2 0 0 2 2 2 1 Ion transport protein PRKCSH_1 PF13015.1 CAM68816.1 - 8.2e-22 77.3 0.2 2e-21 76.0 0.1 1.7 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 CAM68816.1 - 0.0019 18.9 0.1 0.0019 18.9 0.0 2.0 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein Calc_CGRP_IAPP PF00214.14 CAM68816.1 - 0.019 15.0 2.0 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 Calcitonin / CGRP / IAPP family Imm6 PF14434.1 CAM68816.1 - 0.053 13.2 0.2 0.13 11.9 0.1 1.6 1 0 0 1 1 1 0 Immunity protein Imm6 DUF4140 PF13600.1 CAM68816.1 - 2.4 8.6 10.9 12 6.4 2.5 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) APG6 PF04111.7 CAM68816.1 - 6.1 5.8 11.9 1.2 8.1 2.5 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 Dynein_heavy PF03028.10 CAM68818.1 - 3.8e-194 646.6 0.0 2.7e-193 643.8 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 CAM68818.1 - 1.8e-118 395.6 9.4 1.8e-118 395.6 6.5 2.9 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CAM68818.1 - 2.1e-95 318.6 0.0 4.6e-95 317.5 0.0 1.6 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 CAM68818.1 - 1.9e-65 220.4 0.1 5e-65 219.1 0.1 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 CAM68818.1 - 1.5e-59 200.6 0.4 1.5e-59 200.6 0.3 2.0 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 MT PF12777.2 CAM68818.1 - 1.8e-53 181.5 8.7 3.5e-53 180.5 6.0 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 CAM68818.1 - 2.5e-33 115.3 0.0 8.9e-33 113.5 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 CAM68818.1 - 1.3e-24 86.4 0.0 6.3e-07 29.2 0.0 5.9 5 2 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA PF00004.24 CAM68818.1 - 2.7e-06 27.5 0.1 1.6 8.9 0.0 5.0 5 0 0 5 5 4 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CAM68818.1 - 4.9e-06 26.6 11.1 1.1 9.1 0.0 7.6 5 2 2 7 7 7 2 AAA ATPase domain AAA_22 PF13401.1 CAM68818.1 - 1.4e-05 25.1 0.5 6 7.0 0.0 6.3 6 0 0 6 6 6 1 AAA domain AAA_17 PF13207.1 CAM68818.1 - 0.0014 19.4 0.0 7.6 7.3 0.0 5.4 5 0 0 5 5 5 1 AAA domain FtsK_SpoIIIE PF01580.13 CAM68818.1 - 0.003 17.0 7.9 0.012 15.1 0.0 3.9 4 0 0 4 4 4 1 FtsK/SpoIIIE family RNA_helicase PF00910.17 CAM68818.1 - 0.022 14.9 0.0 4.5 7.5 0.0 4.4 4 0 0 4 4 4 0 RNA helicase DUF87 PF01935.12 CAM68818.1 - 0.082 12.7 2.5 0.27 10.9 0.3 3.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_19 PF13245.1 CAM68818.1 - 0.15 11.8 5.8 2.9 7.7 0.0 4.1 4 0 0 4 4 3 0 Part of AAA domain AAA_29 PF13555.1 CAM68818.1 - 0.48 10.0 1.5 1.8 8.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Peptidase_M28 PF04389.12 CAM68820.1 - 0.0019 17.9 0.1 0.0047 16.6 0.1 1.7 1 0 0 1 1 1 1 Peptidase family M28 Fer2 PF00111.22 CAM68821.1 - 6.1e-12 45.1 1.0 9.4e-12 44.5 0.7 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain RRM_1 PF00076.17 CAM68822.1 - 2.1e-07 30.4 0.0 3.7e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM68822.1 - 2.8e-05 24.0 0.0 6.8e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM68822.1 - 0.00052 19.8 0.0 0.00085 19.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.5 CAM68822.1 - 0.0034 17.4 0.0 0.0059 16.6 0.0 1.4 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding TROVE PF05731.6 CAM68827.2 - 4.4e-45 154.0 0.0 1e-44 152.8 0.0 1.6 1 1 0 1 1 1 1 TROVE domain WD40 PF00400.27 CAM68827.2 - 2.2e-23 81.2 22.5 0.001 18.8 0.0 9.8 9 0 0 9 9 9 5 WD domain, G-beta repeat DUF4062 PF13271.1 CAM68827.2 - 9e-05 22.4 0.0 0.00035 20.5 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4062) MFS_1_like PF12832.2 CAM68827.2 - 0.1 12.4 0.1 0.27 11.0 0.1 1.7 1 0 0 1 1 1 0 MFS_1 like family Methyltransf_16 PF10294.4 CAM68827.2 - 0.35 10.3 0.0 0.86 9.0 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase RNA_polI_A34 PF08208.6 CAM68827.2 - 8.6 5.9 0.0 17 5.0 0.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Ax_dynein_light PF10211.4 CAM68828.1 - 3e-53 180.4 5.7 4.2e-53 180.0 3.9 1.2 1 0 0 1 1 1 1 Axonemal dynein light chain IncA PF04156.9 CAM68828.1 - 0.055 13.0 4.3 0.091 12.3 3.0 1.3 1 0 0 1 1 1 0 IncA protein DUF342 PF03961.8 CAM68828.1 - 0.33 9.3 2.7 0.51 8.7 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4570 PF15134.1 CAM68828.1 - 0.53 10.1 5.1 1.1 9.1 3.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4570) DUF904 PF06005.7 CAM68828.1 - 3.3 8.0 9.0 7.4 6.9 0.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF904) HMD PF03201.11 CAM68830.1 - 0.071 13.0 0.9 0.36 10.7 0.1 2.5 2 1 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase PseudoU_synth_2 PF00849.17 CAM68832.1 - 4.5e-15 55.8 0.5 2.1e-07 30.8 0.0 3.8 2 2 0 2 2 2 2 RNA pseudouridylate synthase Remorin_C PF03763.8 CAM68832.1 - 0.22 11.0 1.2 0.45 10.0 0.8 1.5 1 0 0 1 1 1 0 Remorin, C-terminal region zf-RING_2 PF13639.1 CAM68833.1 - 2.3e-08 33.7 8.2 2.2e-07 30.5 1.5 2.5 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.1 CAM68833.1 - 2.7e-07 30.1 6.6 1.2e-06 28.1 1.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAM68833.1 - 1.6e-05 24.7 2.2 1.6e-05 24.7 1.5 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CAM68833.1 - 0.0015 18.1 1.6 0.0015 18.1 1.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CAM68833.1 - 0.0017 18.4 0.9 0.037 14.1 0.3 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CAM68833.1 - 0.0048 16.5 1.7 0.0048 16.5 1.2 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C4H2 PF10146.4 CAM68833.1 - 0.062 13.3 4.0 0.24 11.4 0.1 2.7 2 1 0 2 2 2 0 Zinc finger-containing protein Baculo_IE-1 PF05290.6 CAM68833.1 - 0.08 12.6 0.3 0.08 12.6 0.2 1.6 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Uds1 PF15456.1 CAM68833.1 - 0.086 12.8 8.5 0.2 11.6 5.9 1.5 1 0 0 1 1 1 0 Up-regulated During Septation Snapin_Pallidin PF14712.1 CAM68833.1 - 0.13 12.5 2.3 0.9 9.8 0.1 2.1 2 0 0 2 2 2 0 Snapin/Pallidin Prok-RING_4 PF14447.1 CAM68833.1 - 0.57 9.7 5.6 1.2 8.7 0.7 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Beta_helix PF13229.1 CAM68834.1 - 0.0079 15.9 0.0 2.4 7.8 0.0 2.4 2 0 0 2 2 2 2 Right handed beta helix region Ribosomal_60s PF00428.14 CAM68834.1 - 0.024 15.0 0.5 0.024 15.0 0.4 6.8 7 1 0 7 7 7 0 60s Acidic ribosomal protein FAM176 PF14851.1 CAM68834.1 - 0.062 12.9 9.1 0.23 11.1 1.0 3.2 3 0 0 3 3 3 0 FAM176 family Daxx PF03344.10 CAM68834.1 - 4.1 5.7 12.7 0.42 9.0 0.1 2.5 3 0 0 3 3 3 0 Daxx Family CENP-B_dimeris PF09026.5 CAM68834.1 - 4.4 7.5 25.4 0.71 10.1 0.2 3.3 3 0 0 3 3 3 0 Centromere protein B dimerisation domain DnaJ PF00226.26 CAM68836.1 - 1.5e-21 75.9 0.3 3.1e-21 74.8 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ-X PF14308.1 CAM68836.1 - 2.8e-06 26.7 0.1 9.3e-06 25.0 0.0 1.8 2 0 0 2 2 2 1 X-domain of DnaJ-containing Fer4_19 PF06902.6 CAM68836.1 - 0.079 12.8 0.6 13 5.7 0.0 2.6 2 0 0 2 2 2 0 Divergent 4Fe-4S mono-cluster Aldo_ket_red PF00248.16 CAM68837.1 - 3.7e-34 117.8 0.0 6.6e-28 97.3 0.0 2.1 2 0 0 2 2 2 2 Aldo/keto reductase family LRR_4 PF12799.2 CAM68838.1 - 3.6e-15 55.2 1.8 5.1e-05 22.8 0.1 4.4 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM68838.1 - 1.8e-13 50.0 4.0 0.00046 19.8 1.0 4.3 3 1 0 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 CAM68838.1 - 5.8e-08 31.7 11.7 3 8.2 0.0 7.0 7 0 0 7 7 7 3 Leucine Rich Repeat LRR_7 PF13504.1 CAM68838.1 - 8.4e-05 22.1 10.4 6.1 7.5 0.1 6.0 6 0 0 6 6 6 3 Leucine rich repeat LRR_6 PF13516.1 CAM68838.1 - 0.00018 21.2 5.0 3.2 8.1 0.2 4.6 3 1 1 4 4 4 3 Leucine Rich repeat PTCB-BRCT PF12738.2 CAM68839.2 - 9.5e-08 31.7 0.1 0.0014 18.4 0.0 4.0 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.21 CAM68839.2 - 0.0014 18.7 0.0 7.2 6.8 0.0 4.0 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain Na_Pi_cotrans PF02690.10 CAM68839.2 - 4.2 7.0 4.4 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 Na+/Pi-cotransporter HSP70 PF00012.15 CAM68840.1 - 1.7e-250 832.0 3.9 2e-250 831.9 2.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CAM68840.1 - 5.6e-18 64.6 0.2 3.2e-16 58.8 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 CAM68840.1 - 0.0025 17.6 0.7 0.1 12.4 0.5 3.3 1 1 0 1 1 1 1 Cell division protein FtsA BcrAD_BadFG PF01869.15 CAM68840.1 - 0.011 15.0 0.1 4.6 6.4 0.0 2.5 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.13 CAM68840.1 - 0.012 14.7 0.5 0.081 12.0 0.1 2.5 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase DDR PF08841.5 CAM68840.1 - 0.022 13.5 0.2 2.9 6.6 0.1 2.4 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain DUF45 PF01863.12 CAM68840.1 - 0.15 11.8 0.0 0.47 10.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function DUF45 FYVE PF01363.16 CAM68842.2 - 7.4e-13 48.1 11.5 1.6e-12 47.1 4.2 2.8 2 0 0 2 2 2 1 FYVE zinc finger IBR PF01485.16 CAM68842.2 - 4.5 7.2 12.5 0.37 10.7 4.7 2.1 2 0 0 2 2 2 0 IBR domain DnaJ PF00226.26 CAM68843.1 - 2e-23 81.8 0.2 4.8e-23 80.6 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain DnaJ-X PF14308.1 CAM68843.1 - 1.1e-10 41.1 0.0 2.8e-05 23.5 0.0 2.8 1 1 1 2 2 2 2 X-domain of DnaJ-containing GRAS PF03514.9 CAM68843.1 - 0.046 12.4 0.1 0.087 11.5 0.0 1.3 1 0 0 1 1 1 0 GRAS domain family Cupin_8 PF13621.1 CAM68845.1 - 3.8e-55 187.1 0.0 2.3e-54 184.5 0.0 1.9 1 1 0 1 1 1 1 Cupin-like domain CENP-B_dimeris PF09026.5 CAM68845.1 - 0.018 15.2 2.0 0.051 13.8 1.4 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PgaD PF13994.1 CAM68847.1 - 1.1 8.7 5.4 0.27 10.7 0.3 2.3 2 0 0 2 2 2 0 PgaD-like protein DNA_ligase_OB_2 PF14743.1 CAM68850.1 - 8.2e-21 73.4 0.1 1.7e-20 72.4 0.1 1.6 1 0 0 1 1 1 1 DNA ligase OB-like domain DUF4379 PF14311.1 CAM68850.1 - 1.3e-13 50.4 2.6 1.3e-13 50.4 1.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4379) DNA_ligase_A_M PF01068.16 CAM68850.1 - 5.8e-12 45.4 0.0 5.7e-06 25.8 0.0 2.6 3 0 0 3 3 3 2 ATP dependent DNA ligase domain PhnA_Zn_Ribbon PF08274.7 CAM68850.1 - 0.0045 16.7 3.0 0.65 9.8 1.0 2.5 2 0 0 2 2 2 2 PhnA Zinc-Ribbon mRNA_cap_enzyme PF01331.14 CAM68850.1 - 0.034 13.8 0.0 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain DNA_ligase_A_M PF01068.16 CAM68851.1 - 2.5e-22 79.2 0.0 6.9e-22 77.7 0.0 1.7 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_OB_2 PF14743.1 CAM68851.1 - 4.8e-18 64.5 0.0 9.1e-18 63.7 0.0 1.5 1 0 0 1 1 1 1 DNA ligase OB-like domain DUF4379 PF14311.1 CAM68851.1 - 0.00084 19.1 0.7 0.002 17.9 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4379) Zn-ribbon_8 PF09723.5 CAM68851.1 - 0.0071 16.2 0.4 0.028 14.3 0.3 2.0 1 0 0 1 1 1 1 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 CAM68851.1 - 2.1 8.2 5.8 3.8 7.3 0.1 2.9 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Thioredoxin PF00085.15 CAM68852.1 - 0.01 15.4 0.0 0.071 12.7 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin MutS_IV PF05190.13 CAM68852.1 - 0.029 14.5 0.1 0.062 13.4 0.1 1.5 1 0 0 1 1 1 0 MutS family domain IV MMR_HSR1 PF01926.18 CAM68853.1 - 1e-15 57.6 0.0 6.9e-13 48.5 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CAM68853.1 - 4.1e-06 26.1 0.1 9.5e-05 21.7 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 CAM68853.1 - 0.00081 18.6 0.1 0.0015 17.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 CAM68853.1 - 0.0011 18.3 0.0 1.9 7.9 0.1 2.9 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CAM68853.1 - 0.059 13.1 0.2 0.059 13.1 0.2 2.9 2 1 1 3 3 3 0 Dynamin family Prefoldin PF02996.12 CAM68854.1 - 2.8e-26 91.5 1.9 3.8e-26 91.0 0.9 1.5 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 CAM68854.1 - 0.015 15.0 4.3 0.65 9.7 0.1 2.5 2 1 0 2 2 2 0 Prefoldin subunit KxDL PF10241.4 CAM68854.1 - 0.077 12.8 0.6 6.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF3847 PF12958.2 CAM68854.1 - 0.081 12.6 2.9 7.8 6.3 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) DUF972 PF06156.8 CAM68854.1 - 1.6 9.0 6.8 7.1 7.0 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) WD40 PF00400.27 CAM68856.1 - 6.7e-25 86.0 21.4 1.7e-05 24.5 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat WWE PF02825.15 CAM68856.1 - 1.6e-07 30.6 0.1 4.3e-07 29.2 0.1 1.8 1 1 0 1 1 1 1 WWE domain DnaJ PF00226.26 CAM68857.1 - 3.8e-20 71.3 0.9 7.6e-20 70.4 0.6 1.5 1 0 0 1 1 1 1 DnaJ domain LRR_6 PF13516.1 CAM68858.2 - 1.2e-05 24.9 1.0 0.75 10.0 0.0 5.4 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.2 CAM68858.2 - 0.0058 16.2 0.1 30 4.3 0.0 4.7 5 2 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CAM68858.2 - 0.016 15.1 3.0 10 6.6 0.0 5.0 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_7 PF13504.1 CAM68858.2 - 0.11 12.8 6.8 10 6.8 0.0 5.2 4 0 0 4 4 4 0 Leucine rich repeat LRR_8 PF13855.1 CAM68858.2 - 0.29 10.9 0.4 80 3.0 0.0 4.0 5 0 0 5 5 5 0 Leucine rich repeat DUF4460 PF14687.1 CAM68859.1 - 6.9e-09 35.4 0.5 2.5e-08 33.6 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4460) DUF4461 PF14688.1 CAM68859.1 - 0.013 14.8 4.3 0.46 9.7 0.7 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4461) ELMO_CED12 PF04727.8 CAM68860.1 - 3.4e-42 143.8 0.0 4.7e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family DUF35_N PF12172.3 CAM68860.1 - 0.1 12.5 0.3 0.3 11.0 0.2 1.8 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) MSP1_C PF07462.6 CAM68861.1 - 5.2 5.3 11.6 0.66 8.2 2.6 2.3 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus MORN PF02493.15 CAM68863.1 - 1.2e-46 153.6 126.9 0.0001 21.8 0.3 24.8 26 0 0 26 26 26 20 MORN repeat FYVE PF01363.16 CAM68863.1 - 2.2e-27 94.7 13.3 3.9e-19 68.2 2.6 2.6 2 0 0 2 2 2 2 FYVE zinc finger FYVE_2 PF02318.11 CAM68863.1 - 0.16 11.8 10.8 1.1 9.1 1.5 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger Cyt-b5 PF00173.23 CAM68864.1 - 2.7e-19 68.7 0.0 5.4e-19 67.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3474 PF11960.3 CAM68864.1 - 0.033 14.2 3.0 0.46 10.5 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3474) Shisa PF13908.1 CAM68867.1 - 4.1e-06 27.0 0.5 2.3e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator DUF2668 PF10873.3 CAM68867.1 - 0.0013 18.9 0.0 0.0013 18.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2668) Neur_chan_memb PF02932.11 CAM68867.1 - 0.025 14.4 0.1 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region IncA PF04156.9 CAM68867.1 - 0.031 13.8 0.1 0.031 13.8 0.1 1.5 2 0 0 2 2 2 0 IncA protein SHP PF03579.8 CAM68867.1 - 0.072 12.4 0.2 0.072 12.4 0.1 1.8 2 0 0 2 2 2 0 Small hydrophobic protein Renin_r PF07850.9 CAM68867.1 - 0.44 10.9 2.5 0.83 10.0 0.2 2.3 2 0 0 2 2 2 0 Renin receptor-like protein Prenyltrans PF00432.16 CAM68868.1 - 5.3e-23 80.2 15.5 2e-05 24.0 0.1 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CAM68868.1 - 5.4e-23 81.5 1.3 1.2e-15 57.9 0.0 4.7 3 2 2 5 5 5 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 CAM68868.1 - 1.7e-05 24.7 0.1 0.013 15.5 0.0 2.8 2 1 0 2 2 2 2 Prenyltransferase-like COG7 PF10191.4 CAM68869.1 - 1.1e-10 40.1 9.3 0.0071 14.3 1.7 5.2 5 0 0 5 5 5 5 Golgi complex component 7 (COG7) MoCF_biosynth PF00994.19 CAM68869.1 - 0.0012 18.3 0.1 0.08 12.3 0.0 2.7 2 0 0 2 2 2 1 Probable molybdopterin binding domain AIP3 PF03915.8 CAM68869.1 - 2.1 7.1 6.2 1 8.2 0.0 2.8 3 0 0 3 3 3 0 Actin interacting protein 3 RAP1 PF07218.6 CAM68869.1 - 6.4 4.7 4.7 21 3.0 0.1 2.2 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) PhoD PF09423.5 CAM68870.1 - 0.00027 19.6 0.0 0.012 14.2 0.0 2.3 2 1 0 2 2 2 2 PhoD-like phosphatase stn_TNFRSF12A PF12191.3 CAM68870.1 - 0.46 10.5 2.6 0.55 10.2 0.1 2.1 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Abhydrolase_6 PF12697.2 CAM68873.1 - 3.1e-21 76.2 0.6 5.1e-21 75.6 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CAM68873.1 - 2e-06 27.5 0.0 7.1e-06 25.8 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 CAM68873.1 - 0.0018 17.3 0.0 0.0039 16.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.15 CAM68873.1 - 0.0074 15.8 1.9 1.3 8.5 0.4 3.0 2 1 0 2 2 2 2 alpha/beta hydrolase fold RRM_1 PF00076.17 CAM68874.2 - 1e-16 60.2 0.0 1.8e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM68874.2 - 1.3e-14 53.9 0.0 2.4e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM68874.2 - 1.2e-11 44.3 0.0 1.8e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SEF14_adhesin PF06443.6 CAM68874.2 - 0.043 13.4 0.1 0.087 12.4 0.1 1.5 1 0 0 1 1 1 0 SEF14-like adhesin Glutaredoxin PF00462.19 CAM68875.1 - 6.8e-06 25.9 0.0 2.1e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 CAM68875.1 - 3.1e-05 24.1 0.0 8.8e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_4 PF14834.1 CAM68875.1 - 0.0083 16.0 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CAM68875.1 - 0.029 14.8 0.0 0.081 13.4 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 CAM68875.1 - 0.072 13.1 0.0 0.29 11.1 0.0 2.1 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain 3HCDH_N PF02737.13 CAM68876.1 - 6.1e-49 166.1 4.0 1.1e-48 165.2 2.8 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH PF00378.15 CAM68876.1 - 1.3e-40 139.0 0.1 2.5e-40 138.1 0.1 1.5 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family 3HCDH PF00725.17 CAM68876.1 - 3.3e-36 123.5 0.3 1.3e-23 83.1 0.0 3.0 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 CAM68876.1 - 1.7e-05 24.7 1.4 3.6e-05 23.6 0.4 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 CAM68876.1 - 0.003 17.9 1.6 0.011 16.0 1.1 2.1 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Penicillinase_R PF03965.11 CAM68876.1 - 0.072 13.1 0.1 5.8 7.0 0.0 2.8 2 0 0 2 2 2 0 Penicillinase repressor SNF2_N PF00176.18 CAM68877.1 - 1.3e-30 106.1 0.3 4.8e-21 74.8 0.0 3.1 2 1 0 2 2 2 2 SNF2 family N-terminal domain zf-RING_2 PF13639.1 CAM68877.1 - 3.5e-08 33.1 7.4 1.3e-07 31.3 3.6 2.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 CAM68877.1 - 4.2e-06 26.3 5.7 4.2e-06 26.3 4.0 4.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAM68877.1 - 7.1e-06 25.9 6.1 7.1e-06 25.9 4.2 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.26 CAM68877.1 - 7.5e-06 25.7 0.0 1.5e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 CAM68877.1 - 1.9e-05 24.1 4.5 7.2e-05 22.3 3.1 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 CAM68877.1 - 3.8e-05 23.2 0.0 8.3e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.1 CAM68877.1 - 8.3e-05 22.2 4.9 8.3e-05 22.2 3.4 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CAM68877.1 - 0.00027 20.7 9.8 0.00082 19.1 4.2 2.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CAM68877.1 - 0.013 15.1 2.4 0.036 13.7 1.7 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Peptidase_M3 PF01432.15 CAM68878.1 - 5.8e-116 388.2 0.0 5.8e-115 384.9 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M3 Peptidase_M50B PF13398.1 CAM68878.1 - 0.041 13.2 0.3 0.075 12.4 0.2 1.4 1 0 0 1 1 1 0 Peptidase M50B-like PQQ_2 PF13360.1 CAM68879.1 - 0.0011 18.4 0.5 0.0051 16.2 0.0 2.2 3 0 0 3 3 3 1 PQQ-like domain U-box PF04564.10 CAM68881.1 - 0.00053 19.8 0.0 0.0014 18.4 0.0 1.7 2 0 0 2 2 2 1 U-box domain DUF2019 PF09450.5 CAM68881.1 - 0.075 12.9 0.1 2.4 8.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2019) Circo_capsid PF02443.10 CAM68881.1 - 1.3 8.3 6.8 1.9 7.8 4.7 1.2 1 0 0 1 1 1 0 Circovirus capsid protein Pro_dh PF01619.13 CAM68882.1 - 3.8e-56 190.3 0.7 5.6e-56 189.8 0.5 1.2 1 0 0 1 1 1 1 Proline dehydrogenase AP_endonuc_2 PF01261.19 CAM68882.1 - 0.00056 19.2 0.1 0.022 14.0 0.0 2.8 2 1 1 3 3 3 1 Xylose isomerase-like TIM barrel DUF1133 PF06576.6 CAM68882.1 - 0.086 12.0 0.0 0.32 10.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1133) Equine_IAV_S2 PF06502.6 CAM68882.1 - 0.12 12.2 0.0 0.39 10.6 0.0 1.8 1 0 0 1 1 1 0 Equine infectious anaemia virus S2 protein CTP_transf_1 PF01148.15 CAM68883.1 - 2.4e-61 207.6 20.7 3.2e-61 207.2 14.4 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Ribosomal_S28e PF01200.13 CAM68884.1 - 1.9e-29 101.2 2.8 2.2e-29 100.9 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e Ribosomal_S28e PF01200.13 CAM68885.1 - 1.9e-29 101.2 2.8 2.2e-29 100.9 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e Ribosomal_S28e PF01200.13 CAM68886.1 - 1.9e-29 101.2 2.8 2.2e-29 100.9 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e MIT PF04212.13 CAM68887.1 - 0.011 15.6 0.3 0.041 13.7 0.0 2.1 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain LRR_6 PF13516.1 CAM68888.1 - 1.7e-06 27.4 8.0 0.1 12.7 0.0 6.0 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.28 CAM68888.1 - 2.4e-06 26.8 11.1 0.94 9.7 0.0 6.4 5 1 1 6 6 6 3 Leucine Rich Repeat LRR_4 PF12799.2 CAM68888.1 - 0.0022 17.6 6.0 1.4 8.6 0.1 4.6 4 2 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM68888.1 - 0.14 11.9 6.6 17 5.2 0.0 5.0 4 2 1 5 5 5 0 Leucine rich repeat LRR_7 PF13504.1 CAM68888.1 - 0.41 11.0 16.1 5.8 7.5 0.1 6.3 7 0 0 7 7 7 0 Leucine rich repeat FA_desaturase PF00487.19 CAM68891.1 - 8.1e-26 91.0 25.5 1.5e-25 90.1 17.7 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 CAM68891.1 - 3.6e-13 48.5 0.3 7.1e-13 47.5 0.2 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) GPI2 PF06432.6 CAM68891.1 - 2 7.7 9.9 0.21 10.8 3.2 1.8 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase Pkinase PF00069.20 CAM68894.1 - 7.6e-58 195.6 0.0 1.2e-57 195.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM68894.1 - 2.1e-36 125.3 0.0 3.1e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM68894.1 - 3.9e-07 29.3 0.0 8.6e-05 21.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like PAS PF00989.19 CAM68894.1 - 1.4e-06 28.0 0.0 4.2e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 PAS fold Kdo PF06293.9 CAM68894.1 - 0.00016 20.8 0.0 0.0004 19.5 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_9 PF13426.1 CAM68894.1 - 0.00026 21.3 0.0 0.00089 19.6 0.0 2.0 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.5 CAM68894.1 - 0.0025 17.8 0.0 0.012 15.6 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_10 PF13596.1 CAM68894.1 - 0.0043 17.2 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.1 CAM68894.1 - 0.013 15.3 0.0 0.075 12.9 0.0 2.3 1 0 0 1 1 1 0 PAS domain DUF4079 PF13301.1 CAM68894.1 - 0.038 13.9 0.7 0.097 12.6 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) APH PF01636.18 CAM68894.1 - 0.082 12.6 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ank_4 PF13637.1 CAM68895.1 - 4.4e-08 33.4 8.5 0.051 14.1 0.1 5.6 5 1 0 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CAM68895.1 - 6.4e-08 32.8 0.0 0.021 15.1 0.0 4.2 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CAM68895.1 - 2.3e-05 24.4 7.9 1.8 8.9 0.1 5.9 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CAM68895.1 - 0.006 16.7 4.6 19 5.9 0.0 5.5 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.25 CAM68895.1 - 3.5 7.6 13.8 7.1 6.6 0.2 4.6 4 0 0 4 4 4 0 Ankyrin repeat TPR_14 PF13428.1 CAM68896.1 - 3.1 8.6 8.4 2.1 9.2 0.3 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat ANTAR PF03861.9 CAM68900.1 - 0.33 10.5 5.4 0.5 9.9 0.4 3.0 3 0 0 3 3 3 0 ANTAR domain HEAT PF02985.17 CAM68901.1 - 0.00028 20.7 0.4 1.4 9.1 0.0 4.9 3 0 0 3 3 3 2 HEAT repeat Cnd1 PF12717.2 CAM68901.1 - 0.019 14.8 0.0 0.074 12.9 0.0 2.0 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 CAM68901.1 - 0.029 12.6 0.0 0.061 11.6 0.0 1.5 1 0 0 1 1 1 0 Adaptin N terminal region YcbB PF08664.5 CAM68901.1 - 0.079 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 YcbB domain DNA_binding_1 PF01035.15 CAM68902.1 - 4.6e-19 67.9 0.2 3.1e-18 65.2 0.0 2.2 2 0 0 2 2 2 1 6-O-methylguanine DNA methyltransferase, DNA binding domain zf-C2H2_6 PF13912.1 CAM68903.1 - 0.061 13.2 1.4 0.15 12.0 1.0 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-Di19 PF05605.7 CAM68903.1 - 0.075 13.1 0.0 0.075 13.1 0.0 2.1 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding IBR PF01485.16 CAM68903.1 - 0.17 11.7 1.3 0.27 11.1 0.2 1.8 2 0 0 2 2 2 0 IBR domain Zn_Tnp_IS1595 PF12760.2 CAM68903.1 - 0.6 9.9 6.4 10 6.0 0.0 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF3275 PF11679.3 CAM68906.1 - 2.8 7.4 8.3 8.7 5.9 1.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) Sedlin_N PF04628.8 CAM68907.1 - 5e-06 26.4 0.0 1e-05 25.4 0.0 1.5 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region LINES_N PF14694.1 CAM68908.1 - 0.018 14.3 2.6 4.7 6.3 0.1 3.2 3 0 0 3 3 3 0 Lines N-terminus HEAT_2 PF13646.1 CAM68909.1 - 3.3e-30 104.1 7.1 9.4e-16 57.8 0.3 3.3 2 1 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.11 CAM68909.1 - 1.5e-18 65.3 9.4 0.00086 19.5 0.1 6.0 6 0 0 6 6 6 4 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 CAM68909.1 - 2.4e-10 40.5 1.8 0.00076 19.8 0.7 4.4 3 1 0 3 3 3 2 HEAT-like repeat HEAT PF02985.17 CAM68909.1 - 9.5e-07 28.3 5.0 0.0039 17.1 0.0 5.1 5 1 0 6 6 6 2 HEAT repeat DUF4457 PF14652.1 CAM68910.1 - 6.3e-24 84.5 0.0 8.4e-08 31.5 0.0 5.3 6 0 0 6 6 6 4 Domain of unknown function (DUF4457) 4HBT_2 PF13279.1 CAM68911.1 - 2.9e-12 47.0 0.0 4.8e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 CAM68911.1 - 3.6e-09 36.6 0.0 2e-07 31.0 0.0 2.7 3 0 0 3 3 3 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 CAM68911.1 - 0.028 13.3 0.0 0.2 10.5 0.0 2.0 1 1 0 1 1 1 0 Acyl-ACP thioesterase IncA PF04156.9 CAM68912.1 - 0.0031 17.1 3.1 0.0031 17.1 2.1 3.0 3 0 0 3 3 3 1 IncA protein MT PF12777.2 CAM68912.1 - 0.0045 15.7 0.0 0.01 14.5 0.0 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor T4_tail_cap PF11091.3 CAM68912.1 - 0.025 13.2 0.0 4.9 5.7 0.0 2.4 2 0 0 2 2 2 0 Tail-tube assembly protein DUF3252 PF11623.3 CAM68912.1 - 1.8 8.0 11.7 11 5.4 0.0 5.9 8 0 0 8 8 8 0 Protein of unknown function (DUF3252) DUF812 PF05667.6 CAM68913.1 - 4.5 5.6 13.2 0.0079 14.7 1.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF812) Caudo_TAP PF02413.12 CAM68913.1 - 5.5 7.1 7.5 2.8 8.1 1.1 2.4 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein SCO1-SenC PF02630.9 CAM68914.1 - 1.6e-45 154.7 0.0 2.5e-45 154.2 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.1 CAM68914.1 - 0.00084 19.4 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 CAM68914.1 - 0.0028 17.3 0.0 0.0059 16.2 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family Methyltransf_18 PF12847.2 CAM68917.1 - 8e-14 52.1 0.0 1.7e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAM68917.1 - 9e-14 51.5 0.0 1.5e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAM68917.1 - 1.7e-13 50.4 0.0 8.8e-10 38.3 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CAM68917.1 - 7.9e-11 42.3 0.0 0.00035 21.0 0.0 2.6 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 CAM68917.1 - 1.2e-09 38.5 0.0 1.5e-08 34.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAM68917.1 - 8.3e-07 29.3 0.0 7.3e-06 26.2 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain DREV PF05219.7 CAM68917.1 - 0.00033 19.6 0.0 0.00086 18.2 0.0 1.7 1 1 0 1 1 1 1 DREV methyltransferase CMAS PF02353.15 CAM68917.1 - 0.0077 15.3 0.0 0.015 14.3 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 CAM68917.1 - 0.025 14.6 0.0 0.05 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.12 CAM68917.1 - 0.11 11.4 0.0 0.26 10.3 0.0 1.6 1 0 0 1 1 1 0 O-methyltransferase PHD PF00628.24 CAM68918.1 - 0.00031 20.3 3.9 0.00061 19.4 2.7 1.5 1 0 0 1 1 1 1 PHD-finger ATG22 PF11700.3 CAM68920.1 - 0.048 12.1 0.0 0.082 11.3 0.0 1.3 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like HEAT PF02985.17 CAM68920.1 - 1.1 9.4 4.0 1.5 9.0 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat PQ-loop PF04193.9 CAM68921.1 - 2.3e-20 71.8 1.4 9.4e-15 53.9 0.0 2.6 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.11 CAM68921.1 - 0.082 12.7 2.7 6.8 6.6 0.0 2.4 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Pkinase PF00069.20 CAM68923.1 - 2.6e-13 49.7 0.0 1.1e-10 41.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAM68923.1 - 1.1e-08 34.5 0.3 4.2e-06 26.0 0.0 2.8 2 1 0 2 2 2 1 Protein tyrosine kinase Peptidase_C48 PF02902.14 CAM68924.2 - 2.5e-14 53.4 0.0 5.2e-06 26.2 0.0 2.4 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain HS1_rep PF02218.10 CAM68926.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Repeat in HS1/Cortactin Metallophos PF00149.23 CAM68927.1 - 2.5e-18 66.2 0.1 2.9e-16 59.4 0.1 2.6 3 0 0 3 3 3 2 Calcineurin-like phosphoesterase Pkinase PF00069.20 CAM68928.1 - 3.7e-35 121.3 0.0 1.3e-16 60.5 0.0 3.4 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAM68928.1 - 5.9e-07 28.8 0.0 3.2e-05 23.1 0.0 2.9 4 0 0 4 4 4 1 Protein tyrosine kinase RRM_5 PF13893.1 CAM68930.1 - 0.00084 19.1 0.0 0.036 13.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pet191_N PF10203.4 CAM68931.1 - 0.0018 18.2 3.3 0.12 12.3 0.2 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase assembly protein PET191 MRG PF05712.8 CAM68931.1 - 0.12 11.2 0.3 0.11 11.3 0.2 1.2 1 1 0 1 1 1 0 MRG CHCH PF06747.8 CAM68931.1 - 7.6 6.5 6.9 0.7 9.8 1.0 2.2 3 0 0 3 3 3 0 CHCH domain FtsJ PF01728.14 CAM68932.1 - 2.7e-05 24.2 0.0 5.3e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Cornifin PF02389.10 CAM68934.1 - 2.2e-109 363.7 103.1 1.7e-14 54.0 3.5 9.0 1 1 11 12 12 12 12 Cornifin (SPRR) family Dicty_REP PF05086.7 CAM68934.1 - 0.1 10.3 0.6 0.14 9.8 0.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Arf PF00025.16 CAM68936.1 - 1.3e-22 79.9 0.2 2e-09 36.9 0.0 4.3 4 0 0 4 4 4 3 ADP-ribosylation factor family G-alpha PF00503.15 CAM68936.1 - 4.5e-05 22.3 0.0 0.0023 16.6 0.0 2.4 2 1 0 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.22 CAM68936.1 - 0.00037 19.9 0.0 0.81 9.0 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CAM68936.1 - 0.0018 17.4 0.0 2.5 7.2 0.0 2.7 3 0 0 3 3 3 2 Signal recognition particle receptor beta subunit AAA_29 PF13555.1 CAM68936.1 - 0.005 16.3 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 CAM68936.1 - 0.0064 16.4 0.0 0.076 12.9 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.7 CAM68936.1 - 0.0086 15.7 0.1 1.4 8.5 0.0 2.3 2 0 0 2 2 2 1 NACHT domain Miro PF08477.8 CAM68936.1 - 0.012 16.0 0.0 0.14 12.6 0.0 2.4 3 0 0 3 3 2 0 Miro-like protein ABC_tran PF00005.22 CAM68936.1 - 0.02 15.1 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Ras PF00071.17 CAM68936.1 - 0.02 14.2 0.0 35 3.7 0.0 3.7 3 1 0 3 3 3 0 Ras family AAA_28 PF13521.1 CAM68936.1 - 0.036 14.0 0.0 0.086 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Yip1 PF04893.12 CAM68937.1 - 0.0015 18.0 12.3 0.0024 17.3 8.5 1.3 1 0 0 1 1 1 1 Yip1 domain AAA_16 PF13191.1 CAM68938.1 - 2.7e-08 34.0 6.2 5.2e-07 29.8 0.4 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 CAM68938.1 - 1.5e-06 28.4 0.1 0.025 14.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 CAM68938.1 - 0.034 13.8 0.0 1.7 8.3 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase Miro PF08477.8 CAM68938.1 - 0.071 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein SOBP PF15279.1 CAM68938.1 - 0.79 10.0 8.8 0.19 12.1 3.1 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein Ribosomal_L38e PF01781.13 CAM68939.1 - 6.2e-31 105.9 3.8 7.4e-31 105.7 2.6 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Epimerase PF01370.16 CAM68940.1 - 3.9e-54 183.5 1.1 4.3e-53 180.1 0.8 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CAM68940.1 - 1.8e-24 86.0 0.2 2.1e-20 72.6 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 CAM68940.1 - 6.9e-22 77.6 0.3 2.1e-20 72.7 0.2 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 CAM68940.1 - 6.8e-21 74.1 0.0 2.8e-15 55.7 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 CAM68940.1 - 3.5e-18 65.5 0.0 5.6e-12 45.1 0.0 3.0 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 CAM68940.1 - 2.6e-09 37.3 0.2 2.9e-06 27.4 0.0 3.1 2 1 1 4 4 4 2 NADH(P)-binding adh_short PF00106.20 CAM68940.1 - 0.63 9.9 8.3 0.47 10.3 1.0 3.3 2 1 0 2 2 2 0 short chain dehydrogenase Aminotran_5 PF00266.14 CAM68941.1 - 2.9e-17 62.4 0.0 5.3e-17 61.6 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 CAM68941.1 - 0.00011 20.6 0.0 0.00017 20.0 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 CAM68941.1 - 0.00089 18.3 0.4 0.0015 17.6 0.3 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 CAM68941.1 - 0.026 13.4 0.0 0.072 12.0 0.0 1.6 2 0 0 2 2 2 0 Aminotransferase class I and II DUF2383 PF09537.5 CAM68942.1 - 0.12 12.6 0.5 1.9 8.7 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Sec1 PF00995.18 CAM68943.1 - 3.7e-114 382.4 0.0 4.2e-114 382.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family CN_hydrolase PF00795.17 CAM68945.1 - 1.2e-29 103.0 0.0 1.6e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Abhydrolase_6 PF12697.2 CAM68946.1 - 0.0054 16.6 0.0 0.0088 15.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 CAM68946.1 - 0.037 13.4 0.0 0.074 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Rhabdo_M2 PF04785.7 CAM68946.1 - 0.1 11.6 0.1 0.17 10.9 0.1 1.4 1 0 0 1 1 1 0 Rhabdovirus matrix protein M2 Abhydrolase_5 PF12695.2 CAM68946.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Cauli_DNA-bind PF03310.8 CAM68947.1 - 3.7 7.4 11.5 2.9 7.7 0.3 4.5 4 0 0 4 4 4 0 Caulimovirus DNA-binding protein Surfac_D-trimer PF09006.6 CAM68947.1 - 4.4 7.1 10.1 1.1 9.0 0.0 4.1 4 0 0 4 4 4 0 Lung surfactant protein D coiled-coil trimerisation Transcrip_act PF04949.8 CAM68947.1 - 5.6 6.5 26.2 0.028 14.0 6.6 5.3 5 1 1 6 6 6 0 Transcriptional activator DASH_Dam1 PF08653.5 CAM68947.1 - 5.7 6.7 16.4 4.7 7.0 0.2 6.4 7 0 0 7 7 7 0 DASH complex subunit Dam1 AMH_N PF04709.7 CAM68948.1 - 0.0026 16.7 0.5 0.003 16.5 0.3 1.1 1 0 0 1 1 1 1 Anti-Mullerian hormone, N terminal region PTPlike_phytase PF14566.1 CAM68949.1 - 0.046 13.7 0.7 0.097 12.7 0.5 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate WD40 PF00400.27 CAM68950.2 - 1.8e-12 46.6 8.7 0.00012 21.7 0.2 4.2 3 1 0 3 3 3 3 WD domain, G-beta repeat RNA_pol_3_Rpc31 PF11705.3 CAM68950.2 - 0.00038 20.4 12.0 0.00038 20.4 8.3 1.9 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 QRPTase_C PF01729.14 CAM68950.2 - 0.0026 17.2 0.7 0.0049 16.4 0.5 1.4 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain PQQ_3 PF13570.1 CAM68950.2 - 0.012 15.8 4.3 9.1 6.7 0.1 4.7 4 0 0 4 4 4 0 PQQ-like domain Na_trans_assoc PF06512.8 CAM68950.2 - 1.8 8.4 11.3 0.33 10.9 4.3 2.0 2 0 0 2 2 2 0 Sodium ion transport-associated Cwf_Cwc_15 PF04889.7 CAM68950.2 - 2.4 7.7 24.9 0.35 10.5 11.9 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.6 CAM68950.2 - 3 7.2 21.8 0.16 11.4 10.2 2.0 2 0 0 2 2 2 0 PPP4R2 NOA36 PF06524.7 CAM68950.2 - 3.5 6.7 11.3 7 5.8 7.8 1.4 1 0 0 1 1 1 0 NOA36 protein Ribosomal_L29 PF00831.18 CAM68951.1 - 1e-19 69.9 2.5 1e-19 69.9 1.7 2.1 2 1 0 2 2 2 1 Ribosomal L29 protein MRP-L47 PF06984.8 CAM68951.1 - 0.022 14.6 0.5 0.022 14.6 0.4 2.0 2 0 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Use1 PF09753.4 CAM68951.1 - 0.12 11.7 5.6 0.14 11.5 3.9 1.0 1 0 0 1 1 1 0 Membrane fusion protein Use1 Ribosomal_S9 PF00380.14 CAM68951.1 - 1.1 9.4 6.1 1.9 8.7 4.2 1.5 1 1 0 1 1 1 0 Ribosomal protein S9/S16 Ribosomal_L29 PF00831.18 CAM68952.1 - 1e-19 69.9 2.5 1e-19 69.9 1.7 2.1 2 1 0 2 2 2 1 Ribosomal L29 protein MRP-L47 PF06984.8 CAM68952.1 - 0.022 14.6 0.5 0.022 14.6 0.4 2.0 2 0 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Use1 PF09753.4 CAM68952.1 - 0.12 11.7 5.6 0.14 11.5 3.9 1.0 1 0 0 1 1 1 0 Membrane fusion protein Use1 Ribosomal_S9 PF00380.14 CAM68952.1 - 1.1 9.4 6.1 1.9 8.7 4.2 1.5 1 1 0 1 1 1 0 Ribosomal protein S9/S16 Sec1 PF00995.18 CAM68954.1 - 4.3e-94 316.1 0.0 4.9e-94 315.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family HECT PF00632.20 CAM68955.2 - 1.8e-29 102.9 0.0 3.5e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.23 CAM68955.2 - 3.3e-14 53.0 0.0 1.3e-13 51.1 0.0 2.0 2 0 0 2 2 2 1 SPRY domain zf-RanBP PF00641.13 CAM68955.2 - 1.7e-07 30.1 14.1 2.6e-05 23.2 1.8 2.8 1 1 1 2 2 2 2 Zn-finger in Ran binding protein and others TIP120 PF08623.5 CAM68955.2 - 2.7 7.5 0.0 5.4 6.5 0.0 1.4 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) fn3 PF00041.16 CAM68956.2 - 1.9e-99 325.9 50.1 1.2e-05 25.3 0.3 38.2 41 1 0 41 41 41 23 Fibronectin type III domain Interfer-bind PF09294.5 CAM68956.2 - 1.5e-15 57.1 9.9 1.1 9.3 0.1 14.9 17 0 0 17 17 17 1 Interferon-alpha/beta receptor, fibronectin type III Y_Y_Y PF07495.8 CAM68956.2 - 0.0011 18.6 0.0 2.6 7.8 0.0 5.2 5 0 0 5 5 5 1 Y_Y_Y domain DUF295 PF03478.13 CAM68956.2 - 0.0014 17.9 0.5 9.8 5.6 0.0 5.6 7 0 0 7 7 7 1 Protein of unknown function (DUF295) DUF2369 PF10179.4 CAM68956.2 - 0.065 12.3 1.0 51 2.8 0.0 5.5 7 0 0 7 7 7 0 Uncharacterised conserved protein (DUF2369) DUF616 PF04765.8 CAM68956.2 - 0.2 10.7 0.0 2.4 7.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF616) Spore_GerQ PF09671.5 CAM68956.2 - 0.64 9.7 0.0 2.1 8.0 0.0 1.8 1 0 0 1 1 1 0 Spore coat protein (Spore_GerQ) zf-SNAP50_C PF12251.3 CAM68956.2 - 1.9 7.8 0.1 3.5 6.9 0.0 1.3 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal zf-primase PF09329.6 CAM68957.1 - 1.4e-11 43.8 0.6 2.9e-11 42.7 0.4 1.5 1 0 0 1 1 1 1 Primase zinc finger Mcm10 PF09332.6 CAM68957.1 - 2.2e-06 27.2 5.0 6.6e-06 25.6 3.4 1.7 1 0 0 1 1 1 1 Mcm10 replication factor Lyase_1 PF00206.15 CAM68959.1 - 0.023 13.9 0.1 2.4 7.2 0.0 2.5 2 0 0 2 2 2 0 Lyase DUF3772 PF12607.3 CAM68959.1 - 1 9.0 6.3 1.5 8.5 1.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) BTB PF00651.26 CAM68960.1 - 2.7e-10 40.1 0.1 0.0012 18.7 0.1 3.1 2 2 0 2 2 2 2 BTB/POZ domain BACK PF07707.10 CAM68960.1 - 0.15 11.8 0.1 0.44 10.4 0.0 1.8 2 0 0 2 2 2 0 BTB And C-terminal Kelch Pkinase PF00069.20 CAM68962.1 - 6.9e-44 149.9 0.0 9e-44 149.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM68962.1 - 8.5e-32 110.2 0.0 1.2e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CAM68962.1 - 0.00023 20.2 0.2 0.00042 19.4 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CAM68962.1 - 0.0072 15.3 0.0 0.021 13.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like DUF2513 PF10711.4 CAM68963.2 - 0.049 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Hypothetical protein (DUF2513) RRM_1 PF00076.17 CAM68963.2 - 0.12 12.0 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Stc1 PF12898.2 CAM68965.1 - 2.1 8.4 9.6 1.4 9.0 1.4 2.4 1 1 1 2 2 2 0 Stc1 domain Dala_Dala_lig_C PF07478.8 CAM68967.1 - 8.5e-13 48.1 0.0 1.4e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus SET PF00856.23 CAM68967.1 - 1.7e-12 47.9 0.0 8.6e-11 42.4 0.0 2.4 1 1 0 1 1 1 1 SET domain ATP-grasp_4 PF13535.1 CAM68967.1 - 2.2e-12 47.1 0.0 6.1e-12 45.6 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.17 CAM68967.1 - 0.00041 19.7 0.0 0.00065 19.1 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain PPR_3 PF13812.1 CAM68968.1 - 0.00073 19.6 0.1 0.015 15.5 0.1 3.1 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR PF01535.15 CAM68968.1 - 0.0029 17.4 0.1 0.98 9.5 0.0 3.0 2 0 0 2 2 2 2 PPR repeat Pkinase PF00069.20 CAM68970.1 - 2.9e-49 167.5 0.0 3.7e-49 167.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM68970.1 - 2.3e-34 118.6 0.0 2.8e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PqiA PF04403.8 CAM68972.1 - 6.9e-18 64.7 23.2 3.9e-16 59.0 6.6 3.4 2 1 1 3 3 3 2 Paraquat-inducible protein A FAD_binding_3 PF01494.14 CAM68974.1 - 1.9e-12 46.9 0.0 3.3e-10 39.5 0.0 2.7 2 1 1 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.1 CAM68974.1 - 1.2e-06 28.4 0.0 3.2e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CAM68974.1 - 3.4e-05 22.9 0.0 0.0002 20.3 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 CAM68974.1 - 0.00011 22.5 0.1 0.00025 21.3 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CAM68974.1 - 0.00012 21.0 0.1 0.00033 19.6 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 CAM68974.1 - 0.005 16.7 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CAM68974.1 - 0.027 13.3 0.4 0.051 12.4 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.12 CAM68974.1 - 0.041 12.9 0.0 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 CAM68974.1 - 0.065 13.2 0.0 0.18 11.8 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase zf-CSL PF05207.8 CAM68976.1 - 5.4e-17 61.0 0.5 7e-17 60.6 0.3 1.2 1 0 0 1 1 1 1 CSL zinc finger Bacillus_HBL PF05791.6 CAM68977.1 - 0.0073 15.6 1.0 0.011 15.1 0.7 1.3 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) AAA_13 PF13166.1 CAM68977.1 - 0.02 13.3 0.1 0.026 12.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain CHCH PF06747.8 CAM68980.1 - 0.00075 19.3 10.5 0.2 11.6 3.1 2.5 2 0 0 2 2 2 2 CHCH domain DUF1903 PF08991.5 CAM68980.1 - 0.0032 17.5 6.3 0.089 12.9 0.6 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1903) NHR2 PF08788.6 CAM68980.1 - 0.12 11.8 4.0 0.16 11.5 2.5 1.5 1 1 0 1 1 1 0 NHR2 domain like COX6B PF02297.12 CAM68980.1 - 9.5 6.3 11.1 1.3 9.0 4.7 1.9 2 1 0 2 2 2 0 Cytochrome oxidase c subunit VIb Pkinase PF00069.20 CAM68981.1 - 1.1e-49 168.8 0.0 1.4e-49 168.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM68981.1 - 1.5e-28 99.5 0.0 2.2e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FYVE PF01363.16 CAM68981.1 - 4.9e-09 35.9 13.3 1.2e-08 34.7 9.3 1.6 1 0 0 1 1 1 1 FYVE zinc finger APH PF01636.18 CAM68981.1 - 0.0053 16.5 0.6 0.02 14.6 0.0 2.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CAM68981.1 - 0.012 14.9 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 CAM68981.1 - 0.025 13.9 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.6 CAM68981.1 - 0.19 10.4 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DnaJ PF00226.26 CAM68982.1 - 7.8e-06 25.5 0.0 2.3e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain Peptidase_M9 PF01752.12 CAM68982.1 - 0.7 8.7 3.6 1.1 8.1 2.5 1.2 1 0 0 1 1 1 0 Collagenase S-antigen PF05756.6 CAM68982.1 - 3.6 7.6 6.2 12 5.9 1.3 2.3 2 0 0 2 2 2 0 S-antigen protein Metallophos PF00149.23 CAM68983.1 - 1.1e-32 113.0 0.0 1.5e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase HECT PF00632.20 CAM68984.1 - 4.9e-06 25.9 0.0 0.0022 17.2 0.0 2.8 4 0 0 4 4 4 2 HECT-domain (ubiquitin-transferase) TSC22 PF01166.13 CAM68985.1 - 0.08 12.9 0.3 0.08 12.9 0.2 7.0 6 1 1 7 7 7 0 TSC-22/dip/bun family Filament PF00038.16 CAM68985.1 - 1.1 8.6 85.4 3.6 6.9 0.3 5.9 1 1 2 4 4 4 0 Intermediate filament protein Reo_sigmaC PF04582.7 CAM68985.1 - 5 6.2 25.0 3 6.9 4.8 5.2 1 1 2 5 5 5 0 Reovirus sigma C capsid protein ABC_membrane PF00664.18 CAM68986.1 - 9.9e-88 294.1 27.7 9e-47 159.7 7.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CAM68986.1 - 2e-68 228.9 0.1 2.8e-34 118.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CAM68986.1 - 1.3e-11 44.1 0.4 1.5e-05 24.3 0.0 3.6 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 CAM68986.1 - 9.5e-07 28.1 0.1 0.031 13.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_21 PF13304.1 CAM68986.1 - 9.6e-07 29.0 0.0 0.38 10.6 0.0 4.2 3 1 1 4 4 4 1 AAA domain AAA_29 PF13555.1 CAM68986.1 - 8.6e-06 25.1 1.4 0.056 12.9 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CAM68986.1 - 1.1e-05 26.2 0.0 0.21 12.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 CAM68986.1 - 1.9e-05 23.4 0.0 0.0017 17.0 0.0 2.4 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA PF00004.24 CAM68986.1 - 0.0001 22.5 1.0 0.79 9.9 0.1 3.9 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 CAM68986.1 - 0.00063 18.8 0.1 0.087 11.9 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.1 CAM68986.1 - 0.0022 18.2 0.0 1 9.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CAM68986.1 - 0.0024 18.0 3.8 0.96 9.5 0.1 3.9 2 2 0 2 2 2 1 AAA domain AAA_23 PF13476.1 CAM68986.1 - 0.003 17.9 1.8 2.3 8.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 CAM68986.1 - 0.0035 16.7 1.0 11 5.4 0.0 3.9 4 0 0 4 4 4 0 AAA domain 7TM_GPCR_Srh PF10318.4 CAM68986.1 - 0.0036 16.1 1.6 0.0036 16.1 1.1 2.3 3 0 0 3 3 2 1 Serpentine type 7TM GPCR chemoreceptor Srh AAA_19 PF13245.1 CAM68986.1 - 0.0045 16.6 4.0 2.8 7.7 0.0 4.5 5 0 0 5 5 3 1 Part of AAA domain AAA_5 PF07728.9 CAM68986.1 - 0.0046 16.6 0.1 0.54 9.9 0.0 3.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 CAM68986.1 - 0.0065 16.6 0.2 6.1 7.0 0.1 2.9 2 0 0 2 2 2 0 RNA helicase SbcCD_C PF13558.1 CAM68986.1 - 0.0076 16.1 6.0 2.5 8.0 0.5 4.0 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 CAM68986.1 - 0.0077 16.0 0.5 1.6 8.4 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_16 PF13191.1 CAM68986.1 - 0.014 15.4 0.2 5.8 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain Viral_helicase1 PF01443.13 CAM68986.1 - 0.016 14.7 0.1 10 5.5 0.0 3.1 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase Miro PF08477.8 CAM68986.1 - 0.023 15.1 0.1 11 6.4 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein ATP-synt_ab PF00006.20 CAM68986.1 - 0.025 14.0 1.4 5.2 6.5 0.0 2.8 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.1 CAM68986.1 - 0.027 14.3 0.0 8.8 6.2 0.0 3.0 3 0 0 3 3 2 0 AAA domain G-alpha PF00503.15 CAM68986.1 - 0.033 12.8 0.1 1.8 7.1 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Rad17 PF03215.10 CAM68986.1 - 0.034 12.8 0.1 0.53 8.9 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_28 PF13521.1 CAM68986.1 - 0.05 13.5 0.1 4.4 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 CAM68986.1 - 0.063 12.4 0.0 25 3.9 0.0 3.5 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Abi PF02517.11 CAM68988.1 - 6.3e-19 67.9 0.6 6.3e-19 67.9 0.4 1.6 2 0 0 2 2 2 1 CAAX protease self-immunity AA_kinase PF00696.23 CAM68990.1 - 2.1e-38 132.2 0.5 2.4e-38 132.0 0.3 1.0 1 0 0 1 1 1 1 Amino acid kinase family TPR_14 PF13428.1 CAM68991.1 - 0.00024 21.4 3.5 0.47 11.2 0.0 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 CAM68991.1 - 0.00034 20.9 3.2 0.47 10.8 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.1 CAM68991.1 - 0.0025 17.9 1.3 0.095 12.8 0.0 3.6 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 CAM68991.1 - 0.0075 16.1 6.6 0.68 9.9 0.0 3.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 CAM68991.1 - 0.024 15.0 3.4 1.4 9.5 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 CAM68991.1 - 0.035 14.7 5.8 5.7 7.7 0.1 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 CAM68991.1 - 0.067 13.1 0.2 1.9 8.4 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Meckelin PF09773.4 CAM68992.1 - 0 1128.4 7.5 0 1128.2 5.2 1.0 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) MSC PF09402.5 CAM68992.1 - 0.041 12.5 0.3 0.079 11.6 0.2 1.4 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Fip1 PF05182.8 CAM68992.1 - 0.13 11.5 1.2 0.33 10.2 0.8 1.6 1 0 0 1 1 1 0 Fip1 motif TGT PF01702.13 CAM68993.1 - 9.7e-32 110.1 0.0 2e-31 109.1 0.0 1.5 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase Peptidase_M48 PF01435.13 CAM68994.1 - 2.2e-42 145.1 0.0 3.5e-42 144.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 CAM68994.1 - 0.011 14.7 0.5 0.023 13.6 0.1 1.8 2 0 0 2 2 2 0 BlaR1 peptidase M56 DEAD PF00270.24 CAM68995.2 - 7.6e-37 126.4 0.1 1.3e-36 125.6 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM68995.2 - 1.2e-21 76.2 0.0 4.7e-21 74.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CAM68995.2 - 1.9e-11 43.3 0.2 1.2e-10 40.8 0.2 2.3 2 1 1 3 3 3 1 Domain of unknown function (DUF4217) SNF2_N PF00176.18 CAM68995.2 - 0.00012 21.0 0.1 0.00025 19.9 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 CAM68995.2 - 0.00015 21.7 0.0 0.00068 19.5 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Lysis_S PF04971.7 CAM68996.1 - 0.025 14.2 0.1 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Lysis protein S p450 PF00067.17 CAM68999.1 - 1.5e-53 182.0 0.0 1.9e-53 181.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 CAM69000.1 - 1.3e-64 217.9 0.0 1.7e-64 217.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM69000.1 - 2.1e-27 95.8 0.0 3.3e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RAMP4 PF06624.7 CAM69004.2 - 0.043 13.3 0.6 0.047 13.2 0.4 1.1 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 MM_CoA_mutase PF01642.17 CAM69005.1 - 1.2e-226 752.8 0.2 1.4e-226 752.5 0.2 1.1 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.14 CAM69005.1 - 1.4e-10 41.1 0.1 3.2e-10 39.9 0.1 1.6 1 0 0 1 1 1 1 B12 binding domain HisG_C PF08029.6 CAM69005.1 - 0.01 15.7 0.0 0.033 14.1 0.0 1.9 1 0 0 1 1 1 0 HisG, C-terminal domain TIP120 PF08623.5 CAM69006.1 - 5.8e-08 32.5 2.8 3e-07 30.1 0.0 2.9 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) DUF2435 PF10363.4 CAM69006.1 - 0.011 15.6 3.8 2.4 8.0 0.0 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2435) Tricho_coat PF05892.6 CAM69006.1 - 0.042 13.0 0.1 0.083 12.0 0.0 1.4 1 0 0 1 1 1 0 Trichovirus coat protein HEAT PF02985.17 CAM69006.1 - 0.21 11.7 13.0 10 6.5 0.0 6.2 5 0 0 5 5 5 0 HEAT repeat XPG_I PF00867.13 CAM69008.1 - 3.7e-29 100.6 0.0 6.5e-29 99.8 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CAM69008.1 - 8.9e-27 93.3 0.0 1.9e-26 92.2 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 CAM69008.1 - 3.4e-06 27.1 0.0 1.5e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Sigma70_r1_1 PF03979.9 CAM69008.1 - 0.028 14.3 0.0 0.067 13.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 PP-binding PF00550.20 CAM69012.1 - 2.2e-10 40.6 0.1 3.2e-10 40.1 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 CAM69012.1 - 0.15 12.1 0.5 0.23 11.5 0.3 1.4 1 1 0 1 1 1 0 Acyl-carrier RRM_1 PF00076.17 CAM69016.1 - 1.9e-13 49.8 0.0 2.9e-07 30.0 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM69016.1 - 4.8e-12 45.6 0.0 2.5e-08 33.7 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM69016.1 - 2.3e-07 30.5 0.0 1.6e-05 24.6 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA PF00004.24 CAM69017.1 - 2.6e-36 124.7 0.0 1.2e-35 122.6 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CAM69017.1 - 2e-08 34.4 2.7 0.021 14.8 0.0 4.2 3 1 0 4 4 4 2 AAA ATPase domain AAA_17 PF13207.1 CAM69017.1 - 0.00034 21.4 0.0 0.00079 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CAM69017.1 - 0.0017 18.5 0.0 0.24 11.5 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.9 CAM69017.1 - 0.0032 17.1 0.1 0.014 15.0 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 CAM69017.1 - 0.0053 16.6 0.0 0.023 14.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 CAM69017.1 - 0.0079 14.9 0.0 0.018 13.7 0.0 1.5 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein DUF815 PF05673.8 CAM69017.1 - 0.011 14.6 0.0 1.5 7.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 CAM69017.1 - 0.03 14.0 0.0 1 9.0 0.0 2.4 2 1 1 3 3 3 0 Archaeal ATPase AAA_22 PF13401.1 CAM69017.1 - 0.052 13.6 0.0 1.5 8.9 0.0 2.6 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.7 CAM69017.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Herpes_UL49_5 PF05702.6 CAM69018.1 - 0.026 14.4 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein Nup96 PF12110.3 CAM69019.1 - 3.2e-49 167.5 0.0 5.9e-49 166.7 0.0 1.4 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 CAM69019.1 - 1.5e-21 76.7 0.0 2.6e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase MutS_III PF05192.13 CAM69019.1 - 0.028 14.1 0.1 0.37 10.5 0.0 2.2 2 0 0 2 2 2 0 MutS domain III DUF2959 PF11172.3 CAM69019.1 - 0.56 9.9 0.0 1 9.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) HALZ PF02183.13 CAM69021.1 - 0.033 13.8 0.9 10 5.9 0.0 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper RSS_P20 PF11757.3 CAM69021.1 - 0.087 12.9 0.1 0.14 12.2 0.1 1.5 1 1 0 1 1 1 0 Suppressor of RNA silencing P21-like PhaP_Bmeg PF09602.5 CAM69021.1 - 0.43 10.3 5.8 0.48 10.2 1.4 2.4 1 1 1 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DnaJ PF00226.26 CAM69022.1 - 1.5e-24 85.5 0.4 2.9e-24 84.5 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain PfkB PF00294.19 CAM69023.1 - 2.5e-64 217.3 0.1 2.9e-64 217.0 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 CAM69023.1 - 1.6e-09 37.3 0.0 2.2e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Mur_ligase PF01225.20 CAM69023.1 - 0.002 18.1 0.0 0.055 13.5 0.0 2.6 2 1 0 2 2 2 1 Mur ligase family, catalytic domain Menin PF05053.8 CAM69023.1 - 0.08 11.1 0.4 0.11 10.6 0.3 1.1 1 0 0 1 1 1 0 Menin Vps53_N PF04100.7 CAM69024.1 - 0.027 13.2 1.0 0.041 12.6 0.7 1.1 1 0 0 1 1 1 0 Vps53-like, N-terminal Brix PF04427.13 CAM69026.1 - 2.8e-43 147.8 0.1 6e-43 146.7 0.1 1.5 1 0 0 1 1 1 1 Brix domain Vasohibin PF14822.1 CAM69027.1 - 1.6e-49 168.2 0.0 2.3e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 Vasohibin ABC_membrane_2 PF06472.10 CAM69028.1 - 1.3e-25 90.0 0.4 2e-25 89.5 0.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 CAM69028.1 - 4e-15 56.3 0.0 8.7e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 CAM69028.1 - 5.4e-08 32.3 0.0 6.3e-07 28.8 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain NACHT PF05729.7 CAM69028.1 - 1.3e-06 28.1 0.0 2.4e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_21 PF13304.1 CAM69028.1 - 0.00056 19.9 0.0 0.0023 17.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CAM69028.1 - 0.0015 18.5 0.0 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CAM69028.1 - 0.0022 18.1 0.0 0.72 10.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 CAM69028.1 - 0.0028 18.0 0.0 0.0057 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 CAM69028.1 - 0.0052 16.8 0.0 0.23 11.4 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Miro PF08477.8 CAM69028.1 - 0.012 16.1 0.0 0.032 14.7 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein SbcCD_C PF13558.1 CAM69028.1 - 0.014 15.2 0.0 0.039 13.8 0.0 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF2813 PF11398.3 CAM69028.1 - 0.038 13.0 0.0 0.077 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) AAA_15 PF13175.1 CAM69028.1 - 0.055 12.4 0.0 0.096 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain GRDA PF04723.9 CAM69028.1 - 0.092 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Glycine reductase complex selenoprotein A AAA_29 PF13555.1 CAM69028.1 - 0.13 11.8 0.0 0.31 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Peptidase_C2 PF00648.16 CAM69030.1 - 3.9e-63 213.2 0.0 2.1e-25 89.3 0.0 3.3 3 0 0 3 3 3 3 Calpain family cysteine protease Calpain_III PF01067.17 CAM69030.1 - 1.2e-27 96.3 0.0 1.7e-10 40.6 0.0 3.6 3 0 0 3 3 3 3 Calpain large subunit, domain III TRF PF08558.5 CAM69030.1 - 0.35 10.1 3.4 4.1 6.6 0.5 2.3 2 0 0 2 2 2 0 Telomere repeat binding factor (TRF) phage_tail_N PF08400.5 CAM69030.1 - 0.41 10.3 0.0 36 4.0 0.0 2.8 3 0 0 3 3 3 0 Prophage tail fibre N-terminal DUF372 PF04036.7 CAM69030.1 - 3 7.3 0.0 9.8 5.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF372) KAP_NTPase PF07693.9 CAM69030.1 - 5.1 5.9 0.1 13 4.6 0.1 1.7 1 0 0 1 1 1 0 KAP family P-loop domain Peptidase_C2 PF00648.16 CAM69031.1 - 1.2e-72 244.4 0.0 1.7e-28 99.5 0.0 3.3 3 0 0 3 3 3 3 Calpain family cysteine protease Calpain_III PF01067.17 CAM69031.1 - 1.8e-29 102.2 0.1 8.6e-11 41.6 0.0 4.0 4 0 0 4 4 4 3 Calpain large subunit, domain III phage_tail_N PF08400.5 CAM69031.1 - 0.29 10.8 0.0 37 4.0 0.0 3.9 3 0 0 3 3 3 0 Prophage tail fibre N-terminal STIL_N PF15253.1 CAM69031.1 - 0.56 8.8 0.0 1.1 7.8 0.0 1.4 1 0 0 1 1 1 0 SCL-interrupting locus protein N-terminus ACCA PF03255.9 CAM69032.2 - 0.0017 17.8 15.6 0.24 10.9 0.2 4.5 2 2 2 4 4 4 2 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF4618 PF15397.1 CAM69032.2 - 0.003 16.9 11.8 0.21 10.9 1.6 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4618) Fib_alpha PF08702.5 CAM69032.2 - 0.018 15.1 3.5 3.3 7.8 0.2 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4198 PF10670.4 CAM69032.2 - 0.037 14.0 0.0 13 5.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4198) Integrin_b_cyt PF08725.6 CAM69032.2 - 0.058 12.7 0.0 17 4.9 0.0 2.7 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain HAUS-augmin3 PF14932.1 CAM69032.2 - 0.058 12.5 14.8 0.66 9.1 2.0 3.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 COG2 PF06148.6 CAM69032.2 - 0.13 12.1 5.5 5.4 6.8 0.5 3.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF919 PF06034.6 CAM69032.2 - 0.48 10.0 3.1 31 4.2 0.2 3.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) TBPIP PF07106.8 CAM69032.2 - 0.86 9.1 6.0 9.4 5.7 0.4 2.7 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Transformer PF06495.6 CAM69032.2 - 1.1 9.1 7.2 9 6.1 0.4 2.6 2 0 0 2 2 2 0 Fruit fly transformer protein DUF3807 PF12720.2 CAM69032.2 - 1.2 9.2 16.6 5.4 7.1 3.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) IncA PF04156.9 CAM69032.2 - 1.6 8.2 7.2 6.8 6.2 0.5 3.1 2 0 0 2 2 2 0 IncA protein phage_tail_N PF08400.5 CAM69032.2 - 1.7 8.3 5.8 18 5.0 0.4 2.8 2 0 0 2 2 2 0 Prophage tail fibre N-terminal AAA_13 PF13166.1 CAM69032.2 - 2.1 6.7 6.0 5.6 5.3 0.2 2.2 2 0 0 2 2 2 0 AAA domain Mnd1 PF03962.10 CAM69032.2 - 7.4 6.1 10.4 18 4.9 1.6 3.1 2 0 0 2 2 2 0 Mnd1 family WD40 PF00400.27 CAM69035.1 - 4.3e-06 26.3 11.6 0.00023 20.9 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF1295 PF06966.7 CAM69040.1 - 1.9e-27 96.0 15.0 3.5e-27 95.2 10.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Pep3_Vps18 PF05131.9 CAM69041.2 - 1.9e-08 33.8 0.0 2e-05 24.0 0.0 2.9 2 0 0 2 2 2 2 Pep3/Vps18/deep orange family Clathrin PF00637.15 CAM69041.2 - 1.5e-07 31.1 0.0 5.9e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 Region in Clathrin and VPS Vps39_2 PF10367.4 CAM69041.2 - 3.2e-05 24.0 0.1 6.6e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-C3HC4_2 PF13923.1 CAM69041.2 - 0.0016 18.4 0.4 0.0065 16.4 0.3 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Clathrin_H_link PF13838.1 CAM69041.2 - 0.0064 16.3 0.0 0.022 14.6 0.0 1.9 2 0 0 2 2 2 1 Clathrin-H-link vATP-synt_E PF01991.13 CAM69041.2 - 0.033 13.4 0.0 0.12 11.6 0.0 1.8 1 1 0 1 1 1 0 ATP synthase (E/31 kDa) subunit zf-RING_5 PF14634.1 CAM69041.2 - 2.6 7.8 11.7 0.031 13.9 2.3 2.3 2 1 0 2 2 2 0 zinc-RING finger domain E1_dh PF00676.15 CAM69042.2 - 9.4e-55 185.4 0.0 1.5e-54 184.7 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.19 CAM69042.2 - 4.4e-48 163.1 0.0 7.4e-48 162.3 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DUF778 PF05608.7 CAM69044.1 - 3.8e-43 146.7 0.1 4.5e-43 146.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF778) GATase_4 PF13230.1 CAM69044.1 - 0.046 12.4 0.2 0.061 12.0 0.1 1.1 1 0 0 1 1 1 0 Glutamine amidotransferases class-II ABC2_membrane_3 PF12698.2 CAM69045.1 - 5.5e-65 219.6 38.9 7.6e-41 140.2 10.1 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.22 CAM69045.1 - 5e-53 179.0 0.0 4.6e-28 98.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CAM69045.1 - 1.5e-15 57.9 0.0 1.7e-06 28.1 0.0 4.2 2 2 0 2 2 2 2 AAA domain AAA_15 PF13175.1 CAM69045.1 - 5.2e-06 25.7 0.0 0.48 9.4 0.0 3.9 4 0 0 4 4 4 2 AAA ATPase domain AAA_29 PF13555.1 CAM69045.1 - 2.9e-05 23.4 0.3 0.032 13.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 CAM69045.1 - 8.5e-05 22.9 2.6 0.095 13.0 0.0 2.6 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.14 CAM69045.1 - 0.00022 20.5 0.0 2.6 7.2 0.0 3.6 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 CAM69045.1 - 0.00036 20.4 0.0 0.27 11.1 0.0 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 CAM69045.1 - 0.00073 18.7 0.0 0.023 13.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SRP54 PF00448.17 CAM69045.1 - 0.0038 16.6 0.5 0.65 9.3 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_30 PF13604.1 CAM69045.1 - 0.0058 16.2 0.0 0.11 12.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 CAM69045.1 - 0.0074 15.7 0.1 0.45 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA-like domain Zeta_toxin PF06414.7 CAM69045.1 - 0.017 14.2 0.0 7.8 5.5 0.0 3.1 3 0 0 3 3 3 0 Zeta toxin AAA_16 PF13191.1 CAM69045.1 - 0.077 12.9 0.2 0.57 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain APS_kinase PF01583.15 CAM69045.1 - 0.17 11.5 0.2 0.7 9.5 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase MobB PF03205.9 CAM69045.1 - 0.19 11.4 0.1 6.4 6.4 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 CAM69045.1 - 0.2 11.8 0.1 19 5.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase ABC2_membrane PF01061.19 CAM69045.1 - 1 8.5 52.3 0.019 14.1 11.8 3.9 4 1 0 4 4 4 0 ABC-2 type transporter AAA_13 PF13166.1 CAM69045.1 - 1.3 7.4 0.9 13 4.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 CAM69045.1 - 5.3 6.7 6.0 4.7 6.9 0.0 2.6 3 0 0 3 3 2 0 Domain of unknown function DUF87 ABC_tran PF00005.22 CAM69046.2 - 1.3e-28 100.0 0.0 2.3e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 CAM69046.2 - 1.5e-21 76.8 24.9 8e-21 74.4 17.2 1.9 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.1 CAM69046.2 - 5.1e-05 23.3 0.0 0.0033 17.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CAM69046.2 - 0.0057 16.1 0.1 0.018 14.5 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 CAM69046.2 - 0.0057 15.9 0.0 1.4 8.1 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 CAM69046.2 - 0.0073 15.5 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 CAM69046.2 - 0.015 15.1 0.0 0.15 12.0 0.0 2.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 CAM69046.2 - 0.018 15.4 0.0 0.053 13.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 CAM69046.2 - 0.025 13.6 0.0 2.4 7.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.1 CAM69046.2 - 0.029 13.9 0.0 0.063 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CAM69046.2 - 0.12 12.3 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 CAM69046.2 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain APS_kinase PF01583.15 CAM69046.2 - 0.21 11.2 0.1 0.39 10.3 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase TatD_DNase PF01026.16 CAM69048.1 - 3.6e-38 131.2 0.0 4.4e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.9 CAM69048.1 - 1.3e-06 28.2 0.0 0.00065 19.3 0.0 3.0 1 1 0 1 1 1 1 Amidohydrolase PriCT_1 PF08708.6 CAM69048.1 - 0.00086 19.0 0.0 1.6 8.5 0.0 2.8 2 0 0 2 2 2 2 Primase C terminal 1 (PriCT-1) DUF896 PF05979.7 CAM69050.1 - 0.038 13.5 0.6 0.24 11.0 0.2 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) Pyridox_ox_2 PF12900.2 CAM69050.1 - 0.16 11.7 0.5 4.1 7.2 0.1 2.2 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase AAA PF00004.24 CAM69054.1 - 1.2e-86 287.6 0.0 3.4e-47 159.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CAM69054.1 - 2.7e-16 59.3 0.0 1.3e-08 34.2 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CAM69054.1 - 8.8e-13 48.6 2.0 0.00025 21.0 0.0 4.9 4 2 2 6 6 6 2 AAA ATPase domain AAA_5 PF07728.9 CAM69054.1 - 1.6e-11 44.0 0.2 0.00019 21.1 0.0 3.9 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CAM69054.1 - 4.6e-11 42.9 0.0 2.1e-05 24.5 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CAM69054.1 - 1.5e-10 41.3 0.4 0.0022 18.1 0.0 4.6 3 2 0 3 3 3 2 AAA domain AAA_14 PF13173.1 CAM69054.1 - 1.6e-09 37.7 0.0 0.00067 19.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CAM69054.1 - 4.2e-09 37.2 0.0 0.001 19.9 0.0 2.8 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 CAM69054.1 - 8.5e-09 34.8 0.0 1.7e-05 24.0 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_33 PF13671.1 CAM69054.1 - 1.6e-08 34.4 0.0 0.0066 16.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 CAM69054.1 - 3.6e-07 29.8 0.7 0.018 14.8 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain RNA_helicase PF00910.17 CAM69054.1 - 8.1e-07 29.1 0.0 0.028 14.5 0.0 3.1 3 0 0 3 3 3 2 RNA helicase IstB_IS21 PF01695.12 CAM69054.1 - 8.3e-07 28.5 0.0 0.028 13.8 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 CAM69054.1 - 6.9e-06 26.3 0.0 0.12 12.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 CAM69054.1 - 1.1e-05 25.4 0.0 0.21 11.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 CAM69054.1 - 1.8e-05 23.6 0.0 0.15 10.7 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus NACHT PF05729.7 CAM69054.1 - 2.1e-05 24.2 0.4 0.31 10.7 0.1 3.3 3 0 0 3 3 3 2 NACHT domain AAA_3 PF07726.6 CAM69054.1 - 2.3e-05 24.0 0.0 0.25 10.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 CAM69054.1 - 4e-05 22.8 0.2 0.044 12.9 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 CAM69054.1 - 6.3e-05 22.4 4.9 1.8 7.9 0.0 4.2 2 2 1 4 4 4 2 AAA domain ABC_tran PF00005.22 CAM69054.1 - 0.00018 21.8 0.6 0.32 11.2 0.0 2.9 3 1 0 3 3 2 1 ABC transporter AAA_24 PF13479.1 CAM69054.1 - 0.00021 20.9 0.1 0.095 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 CAM69054.1 - 0.00034 20.1 0.0 0.077 12.4 0.0 3.0 3 0 0 3 3 2 1 Sigma-54 interaction domain NB-ARC PF00931.17 CAM69054.1 - 0.00037 19.4 0.0 0.22 10.3 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain Sigma54_activ_2 PF14532.1 CAM69054.1 - 0.00039 20.4 0.0 0.03 14.3 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain NTPase_1 PF03266.10 CAM69054.1 - 0.00075 19.2 0.2 0.25 11.0 0.0 3.0 3 0 0 3 3 3 1 NTPase AAA_11 PF13086.1 CAM69054.1 - 0.00093 18.8 0.0 0.39 10.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain Vps4_C PF09336.5 CAM69054.1 - 0.0014 18.4 0.1 0.0074 16.1 0.0 2.2 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain Viral_helicase1 PF01443.13 CAM69054.1 - 0.0017 17.9 0.0 0.43 10.0 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Bac_DnaA PF00308.13 CAM69054.1 - 0.0028 17.3 0.1 1.5 8.4 0.0 2.7 2 0 0 2 2 2 1 Bacterial dnaA protein Arch_ATPase PF01637.13 CAM69054.1 - 0.003 17.2 0.0 1.2 8.8 0.0 2.9 2 2 0 2 2 2 1 Archaeal ATPase UPF0079 PF02367.12 CAM69054.1 - 0.0031 17.1 0.0 3 7.4 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Parvo_NS1 PF01057.12 CAM69054.1 - 0.0048 15.8 0.1 0.36 9.6 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 DUF815 PF05673.8 CAM69054.1 - 0.013 14.4 0.0 2.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) SKI PF01202.17 CAM69054.1 - 0.026 14.3 0.0 0.42 10.4 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase Rad17 PF03215.10 CAM69054.1 - 0.042 12.5 0.0 0.23 10.0 0.0 2.0 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_29 PF13555.1 CAM69054.1 - 0.08 12.4 0.0 5.2 6.6 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain KaiC PF06745.8 CAM69054.1 - 0.098 11.7 0.3 2.5 7.1 0.0 2.8 2 1 0 2 2 2 0 KaiC AAA_30 PF13604.1 CAM69054.1 - 0.11 12.1 0.1 19 4.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain Aminotran_5 PF00266.14 CAM69055.1 - 6.4e-87 291.6 0.0 7.6e-87 291.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CAM69055.1 - 1.1e-13 51.0 0.1 1.6e-13 50.4 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.14 CAM69055.1 - 0.0018 16.7 0.1 0.0032 15.9 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.12 CAM69055.1 - 0.004 16.2 0.1 0.006 15.6 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family AAA PF00004.24 CAM69056.1 - 5.3e-37 126.9 0.0 2.8e-27 95.5 0.0 3.6 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CAM69056.1 - 1.2e-13 51.3 0.8 9.8e-07 28.9 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CAM69056.1 - 3.1e-10 40.9 0.0 7.4e-05 23.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CAM69056.1 - 9.5e-10 38.7 3.3 0.00035 20.5 0.2 3.9 2 2 1 3 3 3 2 AAA ATPase domain AAA_18 PF13238.1 CAM69056.1 - 1.6e-08 34.8 0.0 0.0026 18.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 CAM69056.1 - 1.6e-08 34.1 2.9 0.00017 21.2 0.1 3.7 3 0 0 3 3 3 2 Part of AAA domain IstB_IS21 PF01695.12 CAM69056.1 - 7.9e-08 31.9 0.0 0.00092 18.6 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 CAM69056.1 - 8.1e-08 31.6 0.0 0.00055 19.1 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CAM69056.1 - 1e-07 31.7 0.0 0.0064 16.2 0.0 3.0 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CAM69056.1 - 3.5e-07 30.2 0.0 0.037 13.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 CAM69056.1 - 5.7e-07 29.6 0.0 0.0012 18.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 CAM69056.1 - 8.3e-07 28.0 0.0 0.029 13.1 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_30 PF13604.1 CAM69056.1 - 1.3e-06 28.1 0.0 0.00024 20.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.9 CAM69056.1 - 5.1e-06 26.4 0.0 0.00048 20.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF2075 PF09848.4 CAM69056.1 - 6.5e-06 25.3 0.0 0.032 13.2 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 CAM69056.1 - 1.9e-05 24.9 0.0 0.12 12.6 0.0 2.9 3 0 0 3 3 2 2 ABC transporter Sigma54_activat PF00158.21 CAM69056.1 - 2.1e-05 24.0 0.0 0.079 12.4 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.1 CAM69056.1 - 4e-05 23.5 0.0 0.051 13.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 CAM69056.1 - 5.6e-05 23.2 0.0 0.043 13.8 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain RNA_helicase PF00910.17 CAM69056.1 - 0.00018 21.6 0.0 0.61 10.2 0.0 2.5 2 0 0 2 2 2 2 RNA helicase KTI12 PF08433.5 CAM69056.1 - 0.0002 20.6 0.0 0.12 11.5 0.0 2.4 2 0 0 2 2 2 1 Chromatin associated protein KTI12 NB-ARC PF00931.17 CAM69056.1 - 0.00054 18.9 0.0 0.11 11.2 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.1 CAM69056.1 - 0.00072 19.0 0.3 0.14 11.5 0.1 3.4 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.1 CAM69056.1 - 0.0012 18.2 0.0 0.16 11.4 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Zot PF05707.7 CAM69056.1 - 0.0035 16.8 0.2 0.18 11.2 0.0 2.7 2 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_24 PF13479.1 CAM69056.1 - 0.0039 16.8 0.6 1.5 8.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 CAM69056.1 - 0.0043 16.6 0.0 0.024 14.1 0.0 2.1 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase 6PF2K PF01591.13 CAM69056.1 - 0.0044 16.1 0.1 0.5 9.4 0.1 2.2 2 0 0 2 2 2 1 6-phosphofructo-2-kinase NACHT PF05729.7 CAM69056.1 - 0.0046 16.6 0.2 3.8 7.1 0.0 3.2 3 1 0 3 3 2 0 NACHT domain AAA_11 PF13086.1 CAM69056.1 - 0.0049 16.4 0.0 0.23 11.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 CAM69056.1 - 0.0051 15.6 0.7 0.022 13.5 0.2 2.2 2 0 0 2 2 2 1 ArgK protein RuvB_N PF05496.7 CAM69056.1 - 0.0093 15.0 0.0 1.1 8.1 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 CAM69056.1 - 0.014 14.4 0.0 2.9 6.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.10 CAM69056.1 - 0.015 15.0 0.2 0.69 9.6 0.0 2.7 3 0 0 3 3 2 0 NTPase MMR_HSR1 PF01926.18 CAM69056.1 - 0.019 14.9 0.0 0.41 10.6 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.1 CAM69056.1 - 0.021 15.1 0.2 2.1 8.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CAM69056.1 - 0.026 14.2 0.0 0.36 10.4 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase T2SE PF00437.15 CAM69056.1 - 0.029 13.2 0.0 0.18 10.6 0.1 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein VirE PF05272.6 CAM69056.1 - 0.036 13.5 0.0 0.073 12.5 0.0 1.5 1 0 0 1 1 1 0 Virulence-associated protein E DUF815 PF05673.8 CAM69056.1 - 0.037 12.9 0.0 0.14 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.13 CAM69056.1 - 0.038 13.4 0.9 0.31 10.4 0.0 2.7 2 1 1 3 3 3 0 FtsK/SpoIIIE family Parvo_NS1 PF01057.12 CAM69056.1 - 0.12 11.2 0.0 4.8 5.9 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 CAM69056.1 - 0.12 12.0 0.1 5.6 6.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Rad17 PF03215.10 CAM69056.1 - 0.13 10.8 0.0 1.4 7.4 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein PhoH PF02562.11 CAM69056.1 - 0.14 11.4 0.0 7 5.8 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein PPV_E1_C PF00519.12 CAM69056.1 - 0.14 10.7 0.0 7.4 5.0 0.0 2.2 2 0 0 2 2 2 0 Papillomavirus helicase KaiC PF06745.8 CAM69056.1 - 0.31 10.1 1.0 22 4.0 0.2 2.9 2 1 1 3 3 3 0 KaiC EBP PF05241.7 CAM69058.1 - 3.1e-36 124.2 3.3 4.2e-36 123.7 2.3 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF2781 PF10914.3 CAM69058.1 - 2.4 7.9 7.4 3.7 7.3 5.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2781) DUF4239 PF14023.1 CAM69058.1 - 5.6 6.2 8.4 0.91 8.8 2.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) MRP PF09387.5 CAM69060.1 - 2.3e-64 216.7 2.4 2.3e-64 216.7 1.7 2.0 1 1 1 2 2 2 1 Mitochondrial RNA binding protein MRP WGG PF10273.4 CAM69061.1 - 6.1e-05 23.0 1.1 0.00027 20.9 0.8 2.0 1 1 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Nop14 PF04147.7 CAM69061.1 - 0.079 10.8 2.7 0.091 10.6 1.8 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 CAM69061.1 - 0.22 9.9 5.7 0.33 9.3 4.0 1.2 1 0 0 1 1 1 0 Daxx Family DUF2890 PF11081.3 CAM69061.1 - 0.72 9.8 5.4 1.1 9.2 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) TPR_11 PF13414.1 CAM69062.1 - 5.5e-36 122.0 35.7 1.9e-12 46.6 1.7 7.2 7 0 0 7 7 7 6 TPR repeat TPR_12 PF13424.1 CAM69062.1 - 6.1e-31 106.2 32.1 1.8e-07 30.9 0.6 8.0 5 2 1 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.1 CAM69062.1 - 4.7e-28 97.2 26.1 3.9e-07 30.5 0.1 7.4 6 1 1 8 8 7 6 Tetratricopeptide repeat TPR_1 PF00515.23 CAM69062.1 - 8.5e-25 85.3 47.1 5.8e-05 22.5 0.6 11.7 12 0 0 12 12 12 8 Tetratricopeptide repeat TPR_2 PF07719.12 CAM69062.1 - 6.7e-24 81.8 45.3 0.0012 18.5 0.2 12.0 13 0 0 13 13 12 6 Tetratricopeptide repeat TPR_6 PF13174.1 CAM69062.1 - 2.1e-20 71.6 26.9 0.00032 20.9 0.0 11.5 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_19 PF14559.1 CAM69062.1 - 9.2e-19 67.5 27.1 1.4e-05 25.3 0.8 7.8 6 2 3 9 9 9 6 Tetratricopeptide repeat TPR_14 PF13428.1 CAM69062.1 - 3.4e-16 58.2 17.1 0.0011 19.3 0.0 10.2 4 3 8 12 12 12 4 Tetratricopeptide repeat TPR_7 PF13176.1 CAM69062.1 - 2.4e-15 55.0 29.4 0.033 13.9 0.0 10.2 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_8 PF13181.1 CAM69062.1 - 1.9e-13 49.0 34.6 0.014 15.1 0.4 10.6 11 0 0 11 11 11 4 Tetratricopeptide repeat Apc3 PF12895.2 CAM69062.1 - 9.9e-11 41.6 34.2 0.00052 20.1 0.3 7.2 4 2 4 8 8 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 CAM69062.1 - 9e-10 37.9 26.7 0.0027 17.7 0.4 10.1 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_10 PF13374.1 CAM69062.1 - 3.7e-09 36.1 26.9 0.45 10.5 0.0 10.4 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_9 PF13371.1 CAM69062.1 - 0.00011 21.9 4.5 1.9 8.4 0.0 5.7 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.9 CAM69062.1 - 0.00051 20.2 0.3 22 5.8 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CAM69062.1 - 0.38 10.6 20.1 2.2 8.2 0.2 6.7 6 1 1 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat PPR PF01535.15 CAM69062.1 - 0.64 10.1 13.5 17 5.6 0.0 7.6 8 0 0 8 8 8 0 PPR repeat JmjC PF02373.17 CAM69064.1 - 1.2e-10 41.6 4.8 3.6e-09 36.8 3.3 2.3 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 CAM69064.1 - 0.0028 17.2 0.1 0.088 12.2 0.2 2.7 2 1 0 2 2 2 1 Cupin-like domain RAI16-like PF10257.4 CAM69065.1 - 8.1e-08 31.5 0.0 5.6e-06 25.5 0.0 2.4 1 1 0 1 1 1 1 Retinoic acid induced 16-like protein eIF-1a PF01176.14 CAM69066.1 - 0.1 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 PP2C_2 PF13672.1 CAM69067.1 - 0.00014 21.2 4.1 0.0011 18.3 1.2 2.8 2 1 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.7 CAM69067.1 - 0.0025 17.5 1.2 0.015 14.9 0.4 2.6 1 1 1 2 2 2 1 Stage II sporulation protein E (SpoIIE) ASFV_J13L PF05568.6 CAM69067.1 - 4.4 6.7 8.4 40 3.6 5.4 2.2 2 1 0 2 2 2 0 African swine fever virus J13L protein Ribosomal_60s PF00428.14 CAM69067.1 - 5 7.6 13.5 5.5 7.4 6.1 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein CT47 PF15623.1 CAM69068.1 - 5.1 6.7 17.0 6 6.5 11.8 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 HC2 PF07382.6 CAM69068.1 - 8.6 6.1 83.7 1.5e+04 -7.5 32.7 2.1 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 IF-2B PF01008.12 CAM69070.1 - 1.4e-33 116.0 0.0 3.3e-33 114.8 0.0 1.8 2 0 0 2 2 2 1 Initiation factor 2 subunit family DUF3287 PF11690.3 CAM69070.1 - 0.01 15.9 0.6 0.14 12.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3287) Allexi_40kDa PF05549.6 CAM69070.1 - 0.084 12.1 1.2 0.17 11.1 0.1 1.8 1 1 0 2 2 2 0 Allexivirus 40kDa protein AAA_13 PF13166.1 CAM69070.1 - 0.15 10.5 6.8 0.22 9.9 4.7 1.1 1 0 0 1 1 1 0 AAA domain DUF501 PF04417.7 CAM69070.1 - 8.4 6.2 9.2 0.54 10.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF501) WD40 PF00400.27 CAM69075.1 - 6.9e-23 79.6 20.7 2.7e-06 27.0 0.1 6.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Cpn60_TCP1 PF00118.19 CAM69076.1 - 6.6e-138 460.3 9.9 7.6e-138 460.1 6.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cation_efflux PF01545.16 CAM69077.1 - 3.5e-60 203.4 10.1 3.5e-60 203.4 7.0 2.5 2 0 0 2 2 2 1 Cation efflux family UCH PF00443.24 CAM69078.1 - 5.6e-52 176.5 1.5 7.9e-52 176.0 1.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CAM69078.1 - 1.1e-19 70.9 0.3 2.1e-19 70.0 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2197 PF09963.4 CAM69078.1 - 0.043 13.7 0.5 0.18 11.8 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) DUF2296 PF10058.4 CAM69078.1 - 1.5 8.6 5.3 22 4.8 0.8 2.9 3 0 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) DZR PF12773.2 CAM69078.1 - 3.7 7.4 8.9 26 4.7 6.2 2.2 1 1 0 1 1 1 0 Double zinc ribbon Ribonucleas_3_3 PF14622.1 CAM69080.1 - 2.7e-06 27.3 0.0 0.00018 21.4 0.0 2.1 1 1 0 1 1 1 1 Ribonuclease-III-like LRR_6 PF13516.1 CAM69081.1 - 4.2e-20 69.4 10.1 0.014 15.3 0.0 9.0 9 0 0 9 9 9 7 Leucine Rich repeat LRR_4 PF12799.2 CAM69081.1 - 2.4e-12 46.1 1.1 0.00014 21.3 0.1 5.4 3 3 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CAM69081.1 - 1.3e-08 33.6 2.1 0.88 9.8 0.0 8.2 8 1 0 8 8 8 1 Leucine Rich Repeat LRR_8 PF13855.1 CAM69081.1 - 2e-06 27.4 2.0 0.014 15.1 0.2 4.6 3 2 0 3 3 3 1 Leucine rich repeat LRR_7 PF13504.1 CAM69081.1 - 9.1e-05 22.0 7.7 5.7 7.5 0.0 7.5 9 0 0 9 9 9 2 Leucine rich repeat KH_1 PF00013.24 CAM69083.1 - 7.4e-08 31.9 0.0 1.5e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 KH domain zf-CCCH PF00642.19 CAM69083.1 - 0.0012 18.4 2.3 0.0033 17.0 1.6 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Helicase_C PF00271.26 CAM69083.1 - 0.011 15.5 0.1 0.14 11.9 0.1 2.5 1 1 0 1 1 1 0 Helicase conserved C-terminal domain zf-CCCH_2 PF14608.1 CAM69083.1 - 0.012 15.5 1.2 0.024 14.6 0.8 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type SAM_2 PF07647.12 CAM69083.1 - 0.051 13.4 0.0 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) tRNA-synt_1d PF00750.14 CAM69084.1 - 2e-92 309.7 0.0 1e-53 182.4 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.10 CAM69084.1 - 2.5e-27 95.1 2.3 3.5e-26 91.5 0.3 2.7 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 CAM69084.1 - 6e-12 45.9 0.2 2.4e-11 44.0 0.1 2.1 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain Ribosomal_L17 PF01196.14 CAM69084.1 - 0.03 14.8 0.0 0.16 12.6 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L17 Cupin_8 PF13621.1 CAM69085.1 - 1.8e-17 63.7 0.0 5e-17 62.2 0.0 1.7 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 CAM69085.1 - 6.7e-11 42.4 0.1 1.5e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 CAM69085.1 - 0.00084 18.6 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein F-box PF00646.28 CAM69085.1 - 0.0042 16.7 0.4 0.021 14.4 0.4 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 CAM69085.1 - 0.046 13.4 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 F-box-like Cupin_2 PF07883.6 CAM69085.1 - 0.088 12.3 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 Cupin domain Mo25 PF08569.6 CAM69086.1 - 0.038 13.0 0.1 0.06 12.3 0.1 1.4 1 0 0 1 1 1 0 Mo25-like P-mevalo_kinase PF04275.9 CAM69086.1 - 0.081 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Phosphomevalonate kinase FDF PF09532.5 CAM69087.1 - 3.6 8.1 6.1 5.5 7.5 2.8 2.1 1 1 1 2 2 2 0 FDF domain Pkinase PF00069.20 CAM69090.1 - 6.3e-57 192.6 0.0 9.5e-57 192.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM69090.1 - 1.7e-41 142.0 0.0 3.1e-41 141.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM69090.1 - 0.032 13.2 0.0 0.085 11.7 0.0 1.6 1 1 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.6 CAM69090.1 - 0.27 10.0 0.0 0.43 9.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Ribosomal_L10 PF00466.15 CAM69091.1 - 9e-24 83.3 0.2 2e-23 82.2 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 CAM69091.1 - 1.3e-14 54.2 5.3 1.3e-14 54.2 3.7 2.5 3 0 0 3 3 3 1 60s Acidic ribosomal protein DUF1719 PF08224.6 CAM69092.1 - 0.0073 15.4 0.0 0.0082 15.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1719) Choline_kinase PF01633.15 CAM69094.1 - 8.2e-21 74.5 0.0 1.6e-20 73.6 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CAM69094.1 - 5.1e-12 46.0 0.2 1.3e-11 44.7 0.2 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 CAM69094.1 - 0.01 14.9 0.1 0.017 14.2 0.1 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase PF00069.20 CAM69094.1 - 0.011 14.9 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain DUF543 PF04418.7 CAM69095.1 - 3.9e-22 77.9 0.0 4.9e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) TctA PF01970.11 CAM69095.1 - 0.0062 15.0 0.2 0.072 11.4 0.1 1.9 1 1 1 2 2 2 2 Tripartite tricarboxylate transporter TctA family GNAT_acetyltran PF12746.2 CAM69096.1 - 5.2e-54 182.8 0.0 7e-54 182.4 0.0 1.1 1 0 0 1 1 1 1 GNAT acetyltransferase RNA_pol_L_2 PF13656.1 CAM69097.1 - 5.8e-20 70.5 0.0 8e-20 70.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 CAM69097.1 - 1.4e-07 30.5 0.0 2.4e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DAGAT PF03982.8 CAM69098.2 - 2.5e-28 98.6 0.0 4.7e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol acyltransferase FXR1P_C PF12235.3 CAM69098.2 - 0.92 9.6 5.9 1.7 8.7 4.1 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein C terminal Aa_trans PF01490.13 CAM69099.1 - 8.7e-09 34.3 6.1 9.4e-09 34.2 4.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4231 PF14015.1 CAM69099.1 - 0.068 13.1 0.7 0.068 13.1 0.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) DUF4190 PF13828.1 CAM69099.1 - 1 8.9 10.8 0.68 9.5 0.3 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4190) QueT PF06177.6 CAM69099.1 - 1.2 9.0 8.5 2.5 8.0 5.4 1.8 1 1 1 2 2 2 0 QueT transporter Transgly_assoc PF04226.8 CAM69099.1 - 3.3 7.8 10.8 1.4e+02 2.6 7.5 2.7 1 1 0 1 1 1 0 Transglycosylase associated protein DUF2929 PF11151.3 CAM69099.1 - 5 7.2 7.1 2 8.5 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2929) DUF3169 PF11368.3 CAM69099.1 - 8.6 5.4 6.4 3.4 6.8 2.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3169) DUF3099 PF11298.3 CAM69099.1 - 9.6 6.0 8.0 0.58 9.9 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) DAGAT PF03982.8 CAM69100.1 - 1e-29 103.1 0.0 1.3e-29 102.8 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.16 CAM69100.1 - 0.12 11.8 0.0 0.27 10.6 0.0 1.6 1 0 0 1 1 1 0 Acyltransferase Aa_trans PF01490.13 CAM69102.1 - 1.8e-48 165.0 13.1 2.5e-48 164.5 9.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CAM69102.1 - 5.3e-10 38.6 6.8 8.6e-10 37.9 4.7 1.2 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family 7TMR-DISM_7TM PF07695.6 CAM69102.1 - 0.023 14.3 16.1 0.044 13.4 0.2 3.2 1 1 2 3 3 3 0 7TM diverse intracellular signalling IF4E PF01652.13 CAM69104.1 - 2.1e-51 173.7 0.5 2.4e-51 173.5 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E WD40 PF00400.27 CAM69105.1 - 1.5e-15 56.3 0.1 0.0013 18.5 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat BRO1 PF03097.13 CAM69106.1 - 1.3e-67 228.1 0.8 1.3e-67 228.1 0.5 2.6 3 1 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 CAM69106.1 - 2.9e-47 161.0 10.6 2.9e-47 161.0 7.3 2.3 1 1 1 2 2 2 1 ALIX V-shaped domain binding to HIV PAT1 PF09770.4 CAM69106.1 - 0.0016 16.8 37.9 0.0024 16.1 26.2 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 MutS_III PF05192.13 CAM69106.1 - 0.023 14.4 1.7 11 5.6 0.0 2.8 1 1 1 2 2 2 0 MutS domain III DUF3964 PF13107.1 CAM69106.1 - 0.089 13.0 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3964) Strumpellin PF10266.4 CAM69108.1 - 0 1499.5 0.0 0 1499.3 0.0 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin Striatin PF08232.7 CAM69108.1 - 0.066 13.5 0.4 0.16 12.2 0.3 1.6 1 0 0 1 1 1 0 Striatin family ThiF PF00899.16 CAM69109.1 - 3e-43 146.9 0.1 4.8e-43 146.2 0.0 1.3 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 CAM69109.1 - 1.6e-29 101.2 0.2 3.6e-29 100.1 0.1 1.6 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 CAM69109.1 - 0.0001 22.6 0.0 0.00025 21.3 0.0 1.7 1 1 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 CAM69109.1 - 0.0024 17.9 0.2 0.011 15.7 0.1 2.1 1 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 CAM69109.1 - 0.041 12.8 0.2 0.06 12.3 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase 3HCDH_N PF02737.13 CAM69109.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain LRR_9 PF14580.1 CAM69110.1 - 0.016 14.7 0.1 0.03 13.9 0.1 1.4 1 0 0 1 1 1 0 Leucine-rich repeat LRR_4 PF12799.2 CAM69110.1 - 0.26 10.9 7.1 0.28 10.8 0.4 3.1 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_4 PF12799.2 CAM69111.1 - 4.2e-06 26.2 0.3 9.7e-06 25.0 0.0 1.7 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM69111.1 - 0.0031 17.2 0.3 0.0065 16.2 0.2 1.5 1 0 0 1 1 1 1 Leucine rich repeat zf-CCCH_2 PF14608.1 CAM69111.1 - 0.0054 16.6 2.3 0.013 15.4 1.6 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type LRR_1 PF00560.28 CAM69111.1 - 0.012 15.5 0.1 4.4 7.7 0.0 3.0 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_9 PF14580.1 CAM69111.1 - 0.022 14.2 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat LRR_7 PF13504.1 CAM69111.1 - 0.026 14.6 0.1 25 5.6 0.0 3.1 2 0 0 2 2 2 0 Leucine rich repeat zf-CCCH PF00642.19 CAM69111.1 - 0.4 10.4 6.0 0.21 11.3 1.8 2.1 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) ABC2_membrane PF01061.19 CAM69112.1 - 1.2 8.3 23.0 0.037 13.1 11.7 1.6 2 0 0 2 2 2 0 ABC-2 type transporter eRF1_2 PF03464.10 CAM69113.1 - 7.8e-40 136.2 0.0 2.1e-39 134.8 0.0 1.8 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 CAM69113.1 - 9.1e-38 129.0 1.9 1.2e-37 128.6 0.4 1.9 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.10 CAM69113.1 - 1.9e-23 82.4 0.1 3.6e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 ATP-grasp_5 PF13549.1 CAM69113.1 - 0.072 12.2 0.1 0.19 10.8 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain COPIIcoated_ERV PF07970.7 CAM69115.1 - 0.0077 15.8 0.2 0.012 15.2 0.1 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter BAR PF03114.13 CAM69115.1 - 0.0096 15.4 7.5 0.034 13.6 5.2 1.9 1 1 0 1 1 1 1 BAR domain DUF711 PF05167.7 CAM69115.1 - 0.036 12.7 0.1 0.05 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised ACR (DUF711) DUF4510 PF14971.1 CAM69115.1 - 0.044 13.9 0.4 1.8 8.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4510) CotJB PF12652.2 CAM69115.1 - 1 9.5 4.1 4.6 7.3 0.5 3.0 2 1 1 3 3 3 0 CotJB protein DUF1154 PF06631.6 CAM69115.1 - 4.8 6.9 9.9 0.36 10.5 1.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1154) FTA4 PF13093.1 CAM69115.1 - 7 6.0 8.8 6 6.2 0.4 2.6 2 1 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DHC_N2 PF08393.8 CAM69117.1 - 1.7e-108 362.7 1.9 1.7e-108 362.7 1.3 3.9 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 CAM69117.1 - 2.9e-104 349.5 1.0 7.7e-104 348.1 0.0 2.1 2 0 0 2 2 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 CAM69117.1 - 3e-78 262.5 0.1 1.1e-77 260.7 0.0 1.9 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 CAM69117.1 - 1.1e-37 129.1 1.0 2.6e-37 127.8 0.7 1.7 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_5 PF07728.9 CAM69117.1 - 1.3e-31 109.2 0.0 2.9e-20 72.4 0.0 5.8 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_8 PF12780.2 CAM69117.1 - 7.8e-28 97.1 0.0 2.6e-27 95.4 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.2 CAM69117.1 - 8.3e-25 87.2 8.5 1.6e-24 86.2 5.9 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 CAM69117.1 - 1.6e-18 66.7 0.1 3e-17 62.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_16 PF13191.1 CAM69117.1 - 1.6e-14 54.3 3.9 0.0045 16.9 0.0 6.9 6 0 0 6 6 4 4 AAA ATPase domain AAA_22 PF13401.1 CAM69117.1 - 1.9e-13 50.6 0.4 0.045 13.9 0.0 6.5 6 0 0 6 6 5 3 AAA domain AAA PF00004.24 CAM69117.1 - 1e-08 35.4 0.1 0.056 13.6 0.0 5.8 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 CAM69117.1 - 2.9e-08 33.0 0.1 6.3e-06 25.4 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 CAM69117.1 - 3.2e-07 31.1 0.0 0.00057 20.7 0.0 3.8 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.17 CAM69117.1 - 1.4e-06 28.3 0.4 0.36 11.0 0.0 5.1 5 0 0 5 5 5 1 RNA helicase ABC_tran PF00005.22 CAM69117.1 - 5.3e-05 23.5 4.7 0.00042 20.6 0.0 4.3 4 0 0 4 4 2 1 ABC transporter AAA_29 PF13555.1 CAM69117.1 - 6.7e-05 22.3 0.2 0.0074 15.8 0.0 3.7 4 0 0 4 4 4 1 P-loop containing region of AAA domain AAA_19 PF13245.1 CAM69117.1 - 7.1e-05 22.4 0.1 0.11 12.2 0.0 4.4 3 0 0 3 3 3 1 Part of AAA domain AAA_18 PF13238.1 CAM69117.1 - 0.00033 20.9 0.5 0.021 15.1 0.0 3.5 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.1 CAM69117.1 - 0.00036 20.4 2.1 0.013 15.4 0.0 4.4 5 0 0 5 5 3 1 AAA domain Arch_ATPase PF01637.13 CAM69117.1 - 0.00069 19.3 6.1 0.24 11.0 0.0 4.6 4 0 0 4 4 3 1 Archaeal ATPase ATG16 PF08614.6 CAM69117.1 - 0.0009 19.1 3.3 0.0009 19.1 2.3 5.1 4 0 0 4 4 4 2 Autophagy protein 16 (ATG16) AAA_14 PF13173.1 CAM69117.1 - 0.0016 18.3 0.0 3 7.7 0.0 4.8 5 0 0 5 5 4 1 AAA domain Miro PF08477.8 CAM69117.1 - 0.0085 16.5 0.0 16 6.0 0.0 3.7 3 0 0 3 3 3 0 Miro-like protein AAA_21 PF13304.1 CAM69117.1 - 0.016 15.1 0.0 0.047 13.6 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_10 PF12846.2 CAM69117.1 - 0.032 13.6 0.3 0.49 9.7 0.0 3.2 3 0 0 3 3 3 0 AAA-like domain MMR_HSR1 PF01926.18 CAM69117.1 - 0.083 12.8 0.0 0.31 10.9 0.0 2.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase SMC_N PF02463.14 CAM69117.1 - 0.32 10.1 0.0 27 3.8 0.0 2.6 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain L31 PF09784.4 CAM69117.1 - 2.1 8.4 12.1 1.1 9.4 0.1 3.7 3 0 0 3 3 2 0 Mitochondrial ribosomal protein L31 DUF4201 PF13870.1 CAM69117.1 - 2.5 7.4 42.0 0.021 14.2 4.2 5.2 4 0 0 4 4 3 0 Domain of unknown function (DUF4201) Reo_sigmaC PF04582.7 CAM69117.1 - 3 6.9 9.4 14 4.7 0.0 3.2 3 0 0 3 3 3 0 Reovirus sigma C capsid protein IncA PF04156.9 CAM69117.1 - 4.4 6.8 56.3 0.028 14.0 2.5 5.5 4 1 0 4 4 3 0 IncA protein TBCC PF07986.7 CAM69118.1 - 3.1e-24 84.6 3.9 9.6e-18 63.7 4.1 2.4 2 0 0 2 2 2 2 Tubulin binding cofactor C Frag1 PF10277.4 CAM69119.1 - 4.5e-32 111.2 14.7 4.5e-32 111.2 10.2 3.9 3 1 1 4 4 4 2 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.18 CAM69119.1 - 0.0011 19.0 0.0 0.0032 17.4 0.0 1.8 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Aminotran_4 PF01063.14 CAM69120.1 - 5.7e-23 81.6 0.0 7.7e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Erv26 PF04148.8 CAM69121.1 - 1.3e-19 70.4 10.9 9.4e-19 67.6 7.6 1.9 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 Ribonuc_red_sm PF00268.16 CAM69127.1 - 2.5e-111 371.1 0.2 3.2e-111 370.8 0.1 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF3429 PF11911.3 CAM69131.1 - 0.025 14.5 0.3 0.041 13.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3429) RRM_1 PF00076.17 CAM69132.1 - 1.2e-33 114.5 0.0 7.8e-11 41.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM69132.1 - 1.8e-31 107.8 0.1 4.9e-11 42.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM69132.1 - 4.2e-11 42.5 0.0 0.00031 20.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CAM69132.1 - 3e-09 36.4 0.1 0.0029 17.3 0.0 3.2 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif zf-CCHC PF00098.18 CAM69132.1 - 6.6e-05 22.6 0.6 0.00013 21.7 0.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 CAM69132.1 - 0.036 13.7 1.6 0.086 12.5 1.1 1.6 1 0 0 1 1 1 0 Zinc knuckle Lipase_3 PF01764.20 CAM69133.1 - 1.3e-13 50.7 0.0 3.3e-12 46.1 0.0 2.4 1 1 0 1 1 1 1 Lipase (class 3) C1_1 PF00130.17 CAM69133.1 - 7.5e-05 22.3 3.3 0.013 15.2 0.5 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Abhydrolase_5 PF12695.2 CAM69133.1 - 0.018 14.8 0.1 0.044 13.5 0.1 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family C1_2 PF03107.11 CAM69133.1 - 0.073 13.1 0.3 0.073 13.1 0.2 2.0 2 0 0 2 2 2 0 C1 domain DUF2974 PF11187.3 CAM69133.1 - 0.19 11.0 0.0 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) C1_3 PF07649.7 CAM69133.1 - 0.57 10.2 3.5 0.23 11.4 0.3 1.9 2 0 0 2 2 2 0 C1-like domain Motile_Sperm PF00635.21 CAM69134.1 - 2.2e-06 27.2 0.3 6e-06 25.8 0.0 1.9 2 1 0 2 2 2 1 MSP (Major sperm protein) domain Pkinase PF00069.20 CAM69136.1 - 5.5e-31 107.6 0.0 1.2e-28 100.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM69136.1 - 9.4e-13 47.8 0.4 2e-12 46.7 0.3 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CAM69136.1 - 0.00014 21.6 2.2 0.00028 20.6 1.5 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 CAM69136.1 - 0.00099 18.5 0.9 0.0018 17.6 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 CAM69136.1 - 0.0032 16.5 0.1 0.0059 15.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CAM69136.1 - 0.035 13.0 0.3 0.37 9.6 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Pox_ser-thr_kin PF05445.6 CAM69136.1 - 0.31 9.7 0.0 0.46 9.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF605 PF04652.11 CAM69136.1 - 4.2 6.6 9.8 5.7 6.2 6.8 1.2 1 0 0 1 1 1 0 Vta1 like Pkinase PF00069.20 CAM69138.1 - 1.5e-41 142.2 0.0 2.1e-41 141.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM69138.1 - 2.1e-16 59.7 0.0 3.1e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CAM69138.1 - 0.92 8.2 0.0 1.3 7.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PEPCK_ATP PF01293.15 CAM69139.1 - 8.8e-199 660.8 0.0 1.1e-198 660.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 CAM69139.1 - 0.057 13.2 0.1 0.2 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CAM69139.1 - 0.078 12.5 0.1 0.22 11.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain BRCA2 PF00634.13 CAM69139.1 - 0.26 10.6 1.5 0.5 9.6 1.0 1.5 1 0 0 1 1 1 0 BRCA2 repeat TMF_DNA_bd PF12329.3 CAM69140.1 - 0.0026 17.5 2.0 0.0026 17.5 1.4 23.3 14 6 11 26 26 26 8 TATA element modulatory factor 1 DNA binding Cyc-maltodext_C PF10438.4 CAM69140.1 - 0.2 11.7 1.4 29 4.7 0.1 3.0 2 0 0 2 2 2 0 Cyclo-malto-dextrinase C-terminal domain YchF-GTPase_C PF06071.8 CAM69141.1 - 8.7e-21 73.5 0.1 1.7e-20 72.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 CAM69141.1 - 2.3e-18 66.2 0.0 4.2e-18 65.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CAM69141.1 - 1.4e-07 30.9 0.0 2.5e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 CAM69141.1 - 0.0012 18.6 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 TGS domain ABC_tran PF00005.22 CAM69141.1 - 0.0064 16.7 0.0 0.016 15.4 0.0 1.6 1 1 0 1 1 1 1 ABC transporter ArgK PF03308.11 CAM69141.1 - 0.036 12.8 0.0 0.058 12.1 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_10 PF12846.2 CAM69141.1 - 0.044 13.2 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_17 PF13207.1 CAM69141.1 - 0.079 13.7 0.0 0.22 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 CAM69141.1 - 0.13 11.4 0.1 0.34 10.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DSPc PF00782.15 CAM69142.1 - 1.8e-24 85.8 0.0 2.7e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CAM69142.1 - 0.00031 20.1 0.0 0.00053 19.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase N-SET PF11764.3 CAM69142.1 - 0.37 10.6 0.9 0.68 9.8 0.6 1.3 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N Flagellar_rod PF05149.7 CAM69143.2 - 1.2e-111 372.5 24.6 1.2e-111 372.5 17.1 2.1 2 0 0 2 2 2 1 Paraflagellar rod protein SH3_9 PF14604.1 CAM69143.2 - 4.8e-13 48.4 0.0 1e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CAM69143.2 - 3.5e-11 42.3 0.0 6.4e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CAM69143.2 - 3.1e-10 39.3 0.0 5.7e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Mlp PF03304.8 CAM69143.2 - 0.0016 18.5 2.0 0.14 12.1 0.9 2.8 2 0 0 2 2 2 1 Mlp lipoprotein family GSP_synth PF03738.9 CAM69145.1 - 5.6e-27 93.8 0.2 1.1e-26 92.8 0.1 1.5 1 0 0 1 1 1 1 Glutathionylspermidine synthase preATP-grasp CHAP PF05257.11 CAM69145.1 - 1.3e-22 79.7 0.0 3.3e-22 78.4 0.0 1.7 1 0 0 1 1 1 1 CHAP domain CP_ATPgrasp_2 PF14403.1 CAM69145.1 - 0.095 11.3 0.0 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 Circularly permuted ATP-grasp type 2 Mre11_DNA_bind PF04152.9 CAM69147.1 - 7.9e-32 110.4 0.0 2.1e-31 109.0 0.0 1.8 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 CAM69147.1 - 6.1e-18 64.9 0.4 8.7e-18 64.4 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF846 PF05832.7 CAM69149.1 - 1.4e-44 151.2 10.1 1.8e-44 150.9 7.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) TNFR_c6 PF00020.13 CAM69150.1 - 0.46 10.6 5.2 15 5.7 0.0 2.6 2 0 0 2 2 2 0 TNFR/NGFR cysteine-rich region DUF4189 PF13827.1 CAM69150.1 - 0.49 10.6 6.4 0.73 10.1 3.8 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4189) Cmc1 PF08583.5 CAM69150.1 - 0.89 9.3 12.1 1.8 8.3 1.4 3.2 2 1 1 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like Amastin PF07344.6 CAM69152.1 - 0.00023 20.8 1.5 0.00023 20.8 1.0 1.8 2 0 0 2 2 2 1 Amastin surface glycoprotein MIG-14_Wnt-bd PF06664.7 CAM69152.1 - 0.0017 17.2 5.1 0.011 14.5 0.1 2.1 2 0 0 2 2 2 2 Wnt-binding factor required for Wnt secretion Prominin PF05478.6 CAM69152.1 - 0.4 8.1 4.8 0.66 7.4 3.4 1.2 1 0 0 1 1 1 0 Prominin Shisa PF13908.1 CAM69152.1 - 1.9 8.6 5.5 1.2 9.2 2.3 1.7 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Pkinase PF00069.20 CAM69154.1 - 5.8e-46 156.7 0.0 4e-42 144.1 0.0 3.3 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAM69154.1 - 3.5e-23 81.9 0.0 6.5e-22 77.8 0.0 2.4 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM69154.1 - 6.1e-07 28.6 0.0 1.3e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like IFT43 PF15305.1 CAM69156.1 - 9.2e-07 28.9 6.2 9.2e-07 28.9 4.3 2.7 2 2 0 2 2 2 1 Intraflagellar transport protein 43 LSM PF01423.17 CAM69157.1 - 9.5e-17 60.3 0.3 1.2e-16 59.9 0.2 1.1 1 0 0 1 1 1 1 LSM domain FtsJ PF01728.14 CAM69158.1 - 1.9e-57 194.2 0.1 3.1e-57 193.4 0.1 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Spb1_C PF07780.7 CAM69158.1 - 2.7e-33 115.2 17.8 2.7e-33 115.2 12.3 3.6 2 1 2 4 4 4 1 Spb1 C-terminal domain DUF3381 PF11861.3 CAM69158.1 - 2e-28 98.8 3.0 2e-28 98.8 2.0 5.0 4 2 1 6 6 6 1 Domain of unknown function (DUF3381) TrmB PF01978.14 CAM69158.1 - 0.013 15.2 0.3 0.04 13.6 0.2 1.9 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB RabGAP-TBC PF00566.13 CAM69159.1 - 8.7e-29 100.5 0.0 3e-15 56.2 0.0 3.3 3 0 0 3 3 3 3 Rab-GTPase-TBC domain GMP_PDE_delta PF05351.6 CAM69160.1 - 2.6e-63 212.5 0.1 3e-63 212.3 0.0 1.0 1 0 0 1 1 1 1 GMP-PDE, delta subunit IncA PF04156.9 CAM69161.1 - 4.2 6.9 8.3 6 6.4 5.7 1.2 1 0 0 1 1 1 0 IncA protein FAD-oxidase_C PF02913.14 CAM69162.1 - 5e-37 127.5 0.1 8e-37 126.8 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CAM69162.1 - 4.8e-35 120.0 2.1 1.2e-34 118.8 1.4 1.7 1 0 0 1 1 1 1 FAD binding domain PI3_PI4_kinase PF00454.22 CAM69163.2 - 5.8e-14 52.1 0.0 1.1e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase WD40 PF00400.27 CAM69166.1 - 9.2e-15 53.8 5.6 0.00093 18.9 0.4 7.9 9 0 0 9 9 9 3 WD domain, G-beta repeat IncA PF04156.9 CAM69166.1 - 0.006 16.2 26.0 0.006 16.2 18.0 5.0 4 1 1 5 5 5 2 IncA protein Stonin2_N PF12016.3 CAM69166.1 - 0.028 13.6 0.2 0.055 12.6 0.1 1.4 1 0 0 1 1 1 0 Stonin 2 Reo_sigmaC PF04582.7 CAM69166.1 - 0.064 12.4 15.8 0.029 13.5 1.0 3.5 1 1 1 3 3 3 0 Reovirus sigma C capsid protein NIF PF03031.13 CAM69167.1 - 3.2e-29 101.6 0.0 4.8e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase VKOR PF07884.9 CAM69168.1 - 6.5e-12 45.4 20.7 3.2e-11 43.2 14.3 1.8 1 1 0 1 1 1 1 Vitamin K epoxide reductase family Thioredoxin PF00085.15 CAM69169.1 - 1.1e-06 28.1 0.0 2.5e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 CAM69169.1 - 2.2e-05 23.3 0.0 2.4e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Phosducin DSPc PF00782.15 CAM69170.1 - 8e-26 90.1 0.0 1.2e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CAM69170.1 - 0.002 17.5 0.0 0.0031 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Ribosomal_L11_N PF03946.9 CAM69171.1 - 2.3e-14 52.5 0.0 4e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 CAM69171.1 - 2.6e-10 40.2 0.0 5.1e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Atg14 PF10186.4 CAM69173.2 - 0.017 14.0 18.3 0.12 11.2 12.7 2.1 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Med13_N PF11597.3 CAM69173.2 - 0.15 10.7 3.1 0.19 10.3 0.8 1.8 2 0 0 2 2 2 0 Mediator complex subunit 13 N-terminal COG2 PF06148.6 CAM69173.2 - 0.23 11.3 1.9 0.49 10.2 1.3 1.5 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 EMG1 PF03587.9 CAM69174.1 - 2.7e-40 137.8 0.0 3.2e-40 137.6 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Mcp5_PH PF12814.2 CAM69177.1 - 3.8e-16 59.1 0.1 4.5e-16 58.8 0.1 1.1 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.24 CAM69177.1 - 4e-06 26.9 0.3 4.8e-06 26.7 0.2 1.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 CAM69177.1 - 0.66 10.2 3.5 11 6.3 2.4 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain ACOX PF01756.14 CAM69178.1 - 3e-06 26.7 0.0 6.6e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Cupin_3 PF05899.7 CAM69178.1 - 0.1 11.9 0.0 0.3 10.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Spt5-NGN PF03439.8 CAM69179.1 - 3.3e-20 71.6 0.1 3.3e-20 71.6 0.1 2.1 3 0 0 3 3 3 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 CAM69179.1 - 7.8e-07 28.5 4.4 0.028 14.1 0.0 4.3 4 1 0 4 4 4 2 KOW motif Spt5_N PF11942.3 CAM69179.1 - 0.0001 22.8 14.8 0.0001 22.8 10.2 3.0 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal HAS-barrel PF09378.5 CAM69179.1 - 0.00012 21.9 0.1 0.34 10.8 0.0 3.7 3 0 0 3 3 3 2 HAS barrel domain MORN PF02493.15 CAM69180.1 - 7.1e-22 75.7 16.5 1.9e-07 30.4 0.1 5.9 5 1 0 5 5 5 3 MORN repeat DUF1408 PF07193.6 CAM69180.1 - 0.017 14.6 0.0 0.04 13.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1408) HNH_3 PF13392.1 CAM69181.1 - 0.06 12.7 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 HNH endonuclease PP2C PF00481.16 CAM69182.1 - 9.2e-76 254.6 0.0 1.1e-75 254.3 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CAM69182.1 - 0.0044 16.4 0.1 0.025 13.9 0.1 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C SCRL PF06876.7 CAM69182.1 - 0.051 13.5 0.2 0.15 12.0 0.2 1.8 1 0 0 1 1 1 0 Plant self-incompatibility response (SCRL) protein YchF-GTPase_C PF06071.8 CAM69183.1 - 1.4e-36 124.0 0.5 3.1e-36 122.9 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 CAM69183.1 - 4e-17 62.2 0.0 7.2e-17 61.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CAM69183.1 - 0.00011 21.5 0.0 0.00025 20.3 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_17 PF13207.1 CAM69183.1 - 0.0012 19.5 0.3 0.011 16.5 0.2 2.6 1 1 0 1 1 1 1 AAA domain TGS PF02824.16 CAM69183.1 - 0.0052 16.5 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 TGS domain AAA_18 PF13238.1 CAM69183.1 - 0.0086 16.3 0.0 0.03 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 CAM69183.1 - 0.02 13.6 0.0 0.031 13.0 0.0 1.3 1 0 0 1 1 1 0 ArgK protein ABC_tran PF00005.22 CAM69183.1 - 0.076 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter IncA PF04156.9 CAM69184.1 - 5.7 6.4 8.1 16 4.9 5.6 1.5 1 1 0 1 1 1 0 IncA protein Kri1 PF05178.7 CAM69185.1 - 0.034 14.4 3.6 0.055 13.7 2.5 1.3 1 0 0 1 1 1 0 KRI1-like family Exonuc_VII_L PF02601.10 CAM69185.1 - 0.055 12.6 1.5 0.068 12.3 1.1 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1003 PF06210.6 CAM69185.1 - 0.19 11.6 0.8 0.26 11.2 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Med3 PF11593.3 CAM69185.1 - 2 7.5 4.6 2.2 7.4 3.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Dynein_heavy PF03028.10 CAM69186.1 - 8.8e-216 718.2 0.0 1.5e-215 717.4 0.0 1.3 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 CAM69186.1 - 7.7e-115 383.6 4.6 7.7e-115 383.6 3.2 2.9 4 0 0 4 4 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CAM69186.1 - 1.6e-96 322.3 0.3 1.3e-95 319.3 0.0 2.8 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 CAM69186.1 - 1.1e-63 214.7 0.0 2.2e-63 213.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 CAM69186.1 - 1.5e-54 184.2 0.9 3.2e-54 183.1 0.3 1.7 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 CAM69186.1 - 6.1e-52 176.3 0.0 1.1e-51 175.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 MT PF12777.2 CAM69186.1 - 7.8e-24 84.0 11.8 1.7e-23 82.9 8.1 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 CAM69186.1 - 3.4e-20 72.1 0.0 3.9e-05 23.3 0.0 5.8 4 2 1 5 5 5 3 AAA domain (dynein-related subfamily) AAA PF00004.24 CAM69186.1 - 9.3e-09 35.5 2.7 0.004 17.3 0.0 4.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CAM69186.1 - 1.7e-07 31.4 1.2 0.21 11.7 0.0 5.9 5 0 0 5 5 5 2 AAA domain AAA_17 PF13207.1 CAM69186.1 - 0.00021 22.1 0.0 0.0073 17.1 0.0 3.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CAM69186.1 - 0.00025 21.3 0.1 0.12 12.6 0.0 3.7 3 0 0 3 3 3 1 AAA domain UPF0079 PF02367.12 CAM69186.1 - 0.0028 17.2 0.2 0.76 9.4 0.0 3.0 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 CAM69186.1 - 0.0051 16.9 0.7 2.7 8.2 0.0 3.6 3 0 0 3 3 3 1 RNA helicase AAA_16 PF13191.1 CAM69186.1 - 0.13 12.1 0.0 0.13 12.1 0.0 6.5 5 1 1 6 6 5 0 AAA ATPase domain MobB PF03205.9 CAM69186.1 - 0.15 11.7 0.2 1.3 8.7 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B HTH_9 PF08221.6 CAM69187.2 - 0.00017 21.3 0.1 0.01 15.7 0.0 2.8 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 helix-turn-helix domain DUF2582 PF10771.4 CAM69187.2 - 0.053 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2582) KAT11 PF08214.6 CAM69188.1 - 0.07 12.1 0.0 0.088 11.8 0.0 1.3 1 0 0 1 1 1 0 Histone acetylation protein Glyco_hydro_32N PF00251.15 CAM69189.1 - 8.2e-81 271.7 2.8 1e-80 271.4 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 CAM69189.1 - 9.3e-06 25.9 0.0 2.7e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF3315 PF11776.3 CAM69189.1 - 0.037 13.5 1.2 0.69 9.4 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3315) Synaptobrevin PF00957.16 CAM69190.1 - 2.2e-23 81.6 0.5 3e-23 81.2 0.4 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 CAM69190.1 - 3.9e-13 48.7 0.1 7.1e-13 47.9 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain TPR_11 PF13414.1 CAM69194.1 - 8.1e-21 73.4 3.3 5e-14 51.6 0.0 2.9 1 1 1 2 2 2 2 TPR repeat RPAP3_C PF13877.1 CAM69194.1 - 1.4e-19 69.8 0.1 2.7e-19 68.9 0.1 1.5 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_2 PF07719.12 CAM69194.1 - 1.3e-14 52.8 4.1 5.8e-05 22.6 1.3 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 CAM69194.1 - 5.2e-13 48.0 7.4 2.5e-05 23.6 0.6 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 CAM69194.1 - 2.3e-07 30.1 0.2 0.03 14.1 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 CAM69194.1 - 1.2e-06 28.2 3.3 3.1e-06 26.9 0.8 5.1 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 CAM69194.1 - 4.9e-05 23.2 3.7 0.45 10.8 0.0 4.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 CAM69194.1 - 0.00017 21.4 5.9 0.0028 17.5 2.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 CAM69194.1 - 0.00018 22.0 8.2 0.0049 17.4 3.0 4.9 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 CAM69194.1 - 0.00084 19.7 20.0 0.012 16.1 2.2 5.5 3 1 3 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 CAM69194.1 - 0.0081 16.4 0.1 0.0081 16.4 0.0 3.5 4 0 0 4 4 2 2 Tetratricopeptide repeat Apc3 PF12895.2 CAM69194.1 - 0.011 15.8 3.8 0.012 15.7 0.1 2.6 2 1 1 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CAM69194.1 - 0.033 14.6 16.2 0.056 13.9 0.8 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 CAM69194.1 - 5.2 7.1 12.6 14 5.8 0.0 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat DnaJ PF00226.26 CAM69195.1 - 3.4e-28 97.1 0.8 5.9e-28 96.3 0.6 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CAM69195.1 - 9e-19 67.1 0.5 4.2e-15 55.3 0.0 3.5 3 1 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CAM69195.1 - 7.2e-13 48.3 16.5 1.1e-12 47.7 11.4 1.3 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 CAM69195.1 - 0.096 12.3 7.2 2.2 7.9 0.9 2.6 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 CAM69195.1 - 0.27 11.0 9.1 1.2 8.9 1.0 2.4 2 0 0 2 2 2 0 Double zinc ribbon Aldo_ket_red PF00248.16 CAM69196.1 - 3.2e-40 137.7 0.0 3.9e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family TBPIP PF07106.8 CAM69197.1 - 2.1e-08 33.9 0.0 5.7e-08 32.4 0.0 1.6 2 0 0 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) PilJ PF13675.1 CAM69197.1 - 0.057 13.7 0.2 0.13 12.5 0.2 1.6 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term UxaC PF02614.9 CAM69197.1 - 0.063 11.8 0.0 0.11 11.1 0.0 1.3 1 0 0 1 1 1 0 Glucuronate isomerase adh_short PF00106.20 CAM69199.1 - 2e-26 92.8 3.7 2.9e-26 92.3 2.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CAM69199.1 - 2.3e-20 73.4 0.0 2.6e-20 73.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CAM69199.1 - 8.3e-15 54.9 3.4 3.7e-14 52.7 2.4 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 CAM69199.1 - 8.5e-08 31.9 0.1 1.9e-07 30.7 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CAM69199.1 - 0.00081 18.3 0.0 0.47 9.3 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 CAM69199.1 - 0.0087 16.0 0.1 0.013 15.4 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 CAM69199.1 - 0.061 12.1 0.1 0.09 11.6 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Filament PF00038.16 CAM69200.1 - 0.048 13.1 8.1 0.71 9.2 0.3 2.4 2 0 0 2 2 2 0 Intermediate filament protein Prefoldin_2 PF01920.15 CAM69200.1 - 0.3 10.8 4.0 3.2 7.5 0.0 3.4 2 1 0 3 3 3 0 Prefoldin subunit IncA PF04156.9 CAM69200.1 - 0.47 10.0 10.9 0.52 9.8 0.6 2.8 2 1 0 2 2 2 0 IncA protein WXG100 PF06013.7 CAM69200.1 - 0.92 9.5 6.7 0.26 11.3 0.5 2.9 3 0 0 3 3 3 0 Proteins of 100 residues with WXG V-SNARE PF05008.10 CAM69200.1 - 1.5 9.0 6.9 11 6.2 0.5 2.6 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus CCDC-167 PF15188.1 CAM69200.1 - 1.5 8.8 4.7 10 6.1 0.3 3.0 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 LOH1CR12 PF10158.4 CAM69200.1 - 1.5 8.6 9.0 0.19 11.5 0.9 2.9 2 2 0 3 3 3 0 Tumour suppressor protein GAS PF13851.1 CAM69200.1 - 2.2 7.4 5.2 0.69 9.0 0.3 2.4 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding MscS_porin PF12795.2 CAM69200.1 - 3.4 6.9 9.8 1.8 7.8 2.0 2.4 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain Pkinase PF00069.20 CAM69201.1 - 1.6e-17 63.5 0.0 1.9e-17 63.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM69201.1 - 2.5e-09 36.6 0.0 2.8e-09 36.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CAM69201.1 - 0.0056 16.4 0.3 0.0064 16.2 0.2 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family PEPCK_ATP PF01293.15 CAM69202.1 - 8.8e-199 660.8 0.0 1.1e-198 660.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 CAM69202.1 - 0.057 13.2 0.1 0.2 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CAM69202.1 - 0.078 12.5 0.1 0.22 11.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain BRCA2 PF00634.13 CAM69202.1 - 0.26 10.6 1.5 0.5 9.6 1.0 1.5 1 0 0 1 1 1 0 BRCA2 repeat Pkinase PF00069.20 CAM69203.2 - 6.1e-68 228.7 0.0 1e-67 228.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM69203.2 - 4.2e-31 107.9 0.0 6.3e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM69203.2 - 0.00036 19.6 0.0 0.0044 16.0 0.0 2.6 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 CAM69203.2 - 0.15 11.0 0.1 0.39 9.7 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Prp19 PF08606.6 CAM69204.1 - 1.6e-26 91.7 0.5 3.6e-26 90.6 0.3 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 CAM69204.1 - 3.4e-08 33.0 13.0 0.0073 16.1 0.0 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat U-box PF04564.10 CAM69204.1 - 0.0011 18.9 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.3 CAM69204.1 - 0.0012 18.2 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF3312 PF11768.3 CAM69204.1 - 0.008 14.4 0.3 0.14 10.3 0.0 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF3312) Rtf2 PF04641.7 CAM69204.1 - 0.089 11.9 0.4 1 8.4 0.0 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger TTL PF03133.10 CAM69205.1 - 3.9e-49 167.1 0.0 5.5e-49 166.6 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATP-grasp_4 PF13535.1 CAM69205.1 - 0.0014 18.4 0.0 0.023 14.4 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_YheCD PF14398.1 CAM69205.1 - 0.01 14.6 0.0 10 4.8 0.0 3.1 1 1 2 3 3 3 0 YheC/D like ATP-grasp ATPgrasp_Ter PF15632.1 CAM69205.1 - 0.013 14.2 0.0 0.59 8.8 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 CAM69205.1 - 0.018 14.4 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus CP_ATPgrasp_2 PF14403.1 CAM69205.1 - 0.048 12.3 0.0 0.23 10.0 0.0 1.9 2 0 0 2 2 2 0 Circularly permuted ATP-grasp type 2 ATP-grasp_3 PF02655.9 CAM69205.1 - 0.18 11.6 0.0 17 5.2 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp domain XRN_N PF03159.13 CAM69206.1 - 2.4e-19 69.6 0.0 3.4e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XPG_N PF00752.12 CAM69206.1 - 0.045 14.0 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 XPG N-terminal domain Phage_fiber_2 PF03406.8 CAM69206.1 - 0.078 12.6 0.5 0.17 11.5 0.4 1.5 1 0 0 1 1 1 0 Phage tail fibre repeat Acyl-CoA_dh_1 PF00441.19 CAM69207.1 - 5.8e-41 140.0 0.5 1.2e-40 139.0 0.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CAM69207.1 - 4.6e-27 94.8 0.0 1.2e-26 93.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CAM69207.1 - 2.3e-19 68.6 0.1 7.1e-19 67.0 0.1 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CAM69207.1 - 1e-18 67.8 0.1 2.2e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 CAM69207.1 - 0.093 13.0 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal Ribosomal_L10 PF00466.15 CAM69208.1 - 9e-24 83.3 0.2 2e-23 82.2 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 CAM69208.1 - 1.3e-14 54.2 5.3 1.3e-14 54.2 3.7 2.5 3 0 0 3 3 3 1 60s Acidic ribosomal protein VIT1 PF01988.14 CAM69209.1 - 1.1e-59 201.4 4.8 1.5e-59 201.0 3.3 1.1 1 0 0 1 1 1 1 VIT family Proteasome PF00227.21 CAM69211.1 - 1.7e-43 148.0 0.1 2.2e-43 147.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CAM69211.1 - 9.9e-10 37.5 0.1 9.9e-10 37.5 0.1 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature SIT PF15330.1 CAM69212.1 - 0.12 12.4 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT SET PF00856.23 CAM69214.1 - 3.3e-11 43.7 0.4 1e-10 42.1 0.3 1.9 1 1 0 1 1 1 1 SET domain OSTMP1 PF09777.4 CAM69214.1 - 0.088 11.9 0.5 0.12 11.4 0.4 1.2 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor zf-CCCH PF00642.19 CAM69215.1 - 0.0023 17.5 0.4 0.0034 17.0 0.2 1.2 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CDC27 PF09507.5 CAM69215.1 - 0.0073 15.5 1.7 0.0087 15.3 1.2 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Peptidase_S26 PF10502.4 CAM69216.1 - 0.071 12.6 0.1 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 Signal peptidase, peptidase S26 WW PF00397.21 CAM69217.1 - 1.7e-10 40.5 2.0 1.7e-10 40.5 1.4 1.7 2 0 0 2 2 2 1 WW domain zf-CCCH PF00642.19 CAM69217.1 - 1.2e-06 28.0 0.3 1.7e-06 27.5 0.2 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RINGv PF12906.2 CAM69218.1 - 6.7e-10 38.8 11.7 1.4e-09 37.8 8.1 1.5 1 0 0 1 1 1 1 RING-variant domain Macoilin PF09726.4 CAM69219.1 - 0.56 8.4 4.2 0.86 7.8 2.9 1.2 1 0 0 1 1 1 0 Transmembrane protein AAA_4 PF04326.9 CAM69223.1 - 0.0014 18.7 0.0 0.0028 17.7 0.0 1.5 1 0 0 1 1 1 1 Divergent AAA domain Prenyltrans_2 PF13249.1 CAM69223.1 - 0.054 13.8 1.1 0.35 11.2 0.2 2.8 3 1 0 3 3 3 0 Prenyltransferase-like Snf7 PF03357.16 CAM69224.1 - 3e-34 117.8 34.3 3e-34 117.8 23.8 2.0 1 1 1 2 2 2 1 Snf7 DUF2634 PF10934.3 CAM69224.1 - 0.081 12.7 2.6 0.081 12.7 1.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2634) DUF2309 PF10070.4 CAM69224.1 - 0.51 8.3 7.1 0.65 8.0 4.9 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) CENP-Q PF13094.1 CAM69224.1 - 4.5 7.2 15.8 0.79 9.7 7.1 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit CBF PF03914.12 CAM69225.1 - 1.9e-33 115.2 0.1 1.9e-33 115.2 0.1 2.4 2 1 0 2 2 2 1 CBF/Mak21 family DUF2773 PF10971.3 CAM69225.1 - 0.0053 16.6 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2773) Rpn3_C PF08375.6 CAM69226.1 - 3.7e-22 78.4 2.5 5.8e-22 77.8 0.9 1.9 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 CAM69226.1 - 1.3e-17 64.0 0.1 2.5e-17 63.1 0.1 1.5 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.12 CAM69226.1 - 0.058 13.3 0.8 0.18 11.7 0.6 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat PCI_Csn8 PF10075.4 CAM69226.1 - 0.06 13.1 0.0 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 cNMP_binding PF00027.24 CAM69227.1 - 3.6e-13 49.1 0.0 5.7e-08 32.4 0.0 3.3 4 0 0 4 4 4 2 Cyclic nucleotide-binding domain Methyltransf_26 PF13659.1 CAM69228.1 - 0.001 19.1 0.0 0.002 18.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAM69228.1 - 0.0043 17.6 0.0 0.011 16.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Topo_C_assoc PF14370.1 CAM69229.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 C-terminal topoisomerase domain AAA PF00004.24 CAM69230.1 - 1.3e-08 35.1 0.0 1.7e-07 31.5 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CAM69230.1 - 2.9e-07 30.6 0.0 6.2e-06 26.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CAM69230.1 - 0.00085 19.3 0.0 0.0027 17.7 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain T2SE PF00437.15 CAM69230.1 - 0.0014 17.5 0.0 0.0045 15.9 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein Arch_ATPase PF01637.13 CAM69230.1 - 0.008 15.9 0.0 1.8 8.1 0.0 2.2 2 0 0 2 2 2 2 Archaeal ATPase AAA_11 PF13086.1 CAM69230.1 - 0.019 14.5 0.0 0.053 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 CAM69230.1 - 0.085 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.1 CAM69230.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain DUF2075 PF09848.4 CAM69230.1 - 0.13 11.1 0.0 0.26 10.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 CAM69230.1 - 0.18 11.1 0.3 0.67 9.3 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain PPR PF01535.15 CAM69231.1 - 4.3e-05 23.2 0.4 0.22 11.5 0.0 5.7 7 0 0 7 7 7 1 PPR repeat PPR_2 PF13041.1 CAM69231.1 - 0.02 14.8 0.6 1.3 9.0 0.0 3.8 5 0 0 5 5 5 0 PPR repeat family DUF1168 PF06658.7 CAM69231.1 - 0.031 13.8 0.5 0.031 13.8 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) NYD-SP28 PF14772.1 CAM69232.1 - 8e-07 29.1 3.3 8e-07 29.1 2.3 4.7 3 1 2 5 5 5 1 Sperm tail NYD-SP28_assoc PF14775.1 CAM69232.1 - 3.1e-05 23.5 2.0 0.00013 21.5 1.4 2.1 1 0 0 1 1 1 1 Sperm tail C-terminal domain ACCA PF03255.9 CAM69232.1 - 1.9 8.0 9.4 0.11 11.9 1.1 2.8 2 1 1 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit IQ PF00612.22 CAM69235.1 - 3.9e-05 22.9 17.1 0.83 9.4 0.0 5.0 4 0 0 4 4 4 4 IQ calmodulin-binding motif Guanylate_cyc PF00211.15 CAM69236.1 - 1e-24 86.9 0.0 2.4e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Globin PF00042.17 CAM69236.1 - 4.2e-11 43.1 0.2 1.5e-05 25.2 0.0 2.6 2 0 0 2 2 2 2 Globin DUF4234 PF14018.1 CAM69237.1 - 0.013 15.2 0.0 0.016 14.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) Proteasome PF00227.21 CAM69238.1 - 5.5e-40 136.6 0.0 6.2e-40 136.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit RNA_POL_M_15KD PF02150.11 CAM69239.1 - 0.0003 20.4 6.5 0.0003 20.4 4.5 2.5 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.13 CAM69239.1 - 0.0004 19.9 2.5 0.0004 19.9 1.7 3.2 3 2 0 3 3 3 1 Transcription factor S-II (TFIIS) zf-Sec23_Sec24 PF04810.10 CAM69239.1 - 0.0077 15.7 4.8 0.0077 15.7 3.4 1.9 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Ogr_Delta PF04606.7 CAM69239.1 - 0.0098 15.5 0.8 0.0098 15.5 0.6 2.6 2 2 0 2 2 1 1 Ogr/Delta-like zinc finger Zn_Tnp_IS1595 PF12760.2 CAM69239.1 - 0.035 13.9 1.1 0.035 13.9 0.7 2.7 2 2 0 2 2 2 0 Transposase zinc-ribbon domain FdhE PF04216.7 CAM69239.1 - 0.082 12.6 0.4 0.082 12.6 0.3 1.9 2 1 0 2 2 2 0 Protein involved in formate dehydrogenase formation zf-ribbon_3 PF13248.1 CAM69239.1 - 0.18 11.0 9.4 1.2 8.4 0.9 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 CAM69239.1 - 0.86 9.6 9.1 0.31 11.0 0.3 3.3 3 0 0 3 3 3 0 Zinc ribbon domain DZR PF12773.2 CAM69239.1 - 1 9.2 10.7 3.8 7.3 4.3 2.7 1 1 1 2 2 2 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 CAM69239.1 - 1.5 8.4 11.4 0.42 10.1 0.3 3.1 2 1 0 2 2 2 0 zinc-ribbon domain HypA PF01155.14 CAM69239.1 - 3.6 7.3 6.2 20 4.8 4.3 2.1 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family C1_1 PF00130.17 CAM69239.1 - 3.7 7.3 9.1 0.28 10.9 2.2 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_recom PF13408.1 CAM69239.1 - 5.2 7.4 11.1 0.36 11.1 2.1 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Lar_restr_allev PF14354.1 CAM69239.1 - 9.7 6.5 14.8 0.18 12.1 1.6 2.5 2 1 0 2 2 2 0 Restriction alleviation protein Lar Fumble PF03630.9 CAM69241.1 - 1.5e-74 250.9 0.0 2.5e-74 250.1 0.0 1.3 1 0 0 1 1 1 1 Fumble Exo_endo_phos PF03372.18 CAM69241.1 - 8e-16 58.7 0.0 1.7e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AMP-binding PF00501.23 CAM69241.1 - 1.9e-14 52.9 1.1 4.7e-09 35.1 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Exo_endo_phos_2 PF14529.1 CAM69241.1 - 0.16 11.6 0.0 0.39 10.3 0.0 1.8 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase MFS_1 PF07690.11 CAM69242.1 - 2.4e-33 115.3 56.6 4.6e-26 91.3 24.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CAM69242.1 - 0.00055 18.6 30.0 0.0007 18.2 20.3 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter DUF3366 PF11846.3 CAM69242.1 - 1.5 8.6 6.2 9.8 5.9 0.0 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF3366) DUF1678 PF07913.6 CAM69243.1 - 0.016 14.7 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1678) RRM_1 PF00076.17 CAM69243.1 - 0.018 14.6 0.0 0.11 12.1 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.1 CAM69243.1 - 0.048 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Sporulation protein family 7 DSPc PF00782.15 CAM69244.1 - 3.3e-27 94.6 0.0 5e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain LRR_8 PF13855.1 CAM69244.1 - 1e-07 31.6 13.1 0.001 18.8 2.4 3.7 3 0 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 CAM69244.1 - 7.5e-05 22.2 5.1 7.5e-05 22.2 3.5 3.6 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) Y_phosphatase PF00102.22 CAM69244.1 - 0.00055 19.3 0.0 0.00089 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase LRR_7 PF13504.1 CAM69244.1 - 0.0011 18.8 11.4 0.026 14.6 0.4 5.0 5 0 0 5 5 5 1 Leucine rich repeat LRR_1 PF00560.28 CAM69244.1 - 0.0099 15.7 16.1 0.6 10.3 0.2 5.2 5 0 0 5 5 5 2 Leucine Rich Repeat CDKN3 PF05706.7 CAM69244.1 - 0.083 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.1 CAM69244.1 - 0.17 12.1 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family LRR_6 PF13516.1 CAM69244.1 - 0.4 10.8 3.1 19 5.7 0.2 3.9 4 0 0 4 4 4 0 Leucine Rich repeat Histone PF00125.19 CAM69248.1 - 1e-14 54.3 0.8 1.3e-14 53.9 0.6 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CAM69248.1 - 0.012 15.6 0.3 0.021 14.8 0.2 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Cylicin_N PF15241.1 CAM69248.1 - 0.045 13.6 0.1 0.063 13.1 0.1 1.3 1 0 0 1 1 1 0 Cylicin N-terminus DUF2094 PF09867.4 CAM69248.1 - 0.061 13.2 0.1 0.1 12.4 0.1 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2094) zf-DHHC PF01529.15 CAM69249.1 - 2.4e-32 111.7 1.1 2.4e-32 111.7 0.7 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase DAO PF01266.19 CAM69251.2 - 2.3e-38 132.0 0.1 4.1e-38 131.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CAM69251.2 - 0.014 15.2 0.7 0.098 12.5 0.1 2.6 3 1 1 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CAM69251.2 - 0.019 14.0 1.5 0.032 13.3 1.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 CAM69251.2 - 0.027 14.1 0.2 0.063 12.9 0.1 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 CAM69251.2 - 0.095 12.7 1.3 0.38 10.8 0.9 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain dsrm PF00035.20 CAM69251.2 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 Double-stranded RNA binding motif Carboxyl_trans PF01039.17 CAM69252.1 - 3.7e-24 84.9 0.0 4.2e-24 84.7 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain Carboxyl_trans PF01039.17 CAM69253.1 - 2.5e-58 197.6 0.0 2.7e-58 197.5 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 CAM69253.1 - 0.0013 17.9 0.0 0.0015 17.7 0.0 1.1 1 0 0 1 1 1 1 Malonate decarboxylase gamma subunit (MdcE) Carb_anhydrase PF00194.16 CAM69254.1 - 4e-19 68.6 0.0 9e-19 67.4 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Dicty_REP PF05086.7 CAM69254.1 - 0.25 9.0 2.0 0.34 8.6 1.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein WD40 PF00400.27 CAM69255.1 - 0.019 14.8 0.9 2.7 8.0 0.1 4.0 4 0 0 4 4 4 0 WD domain, G-beta repeat RNB PF00773.14 CAM69257.1 - 1.2e-86 291.0 0.0 1.6e-86 290.5 0.0 1.2 1 0 0 1 1 1 1 RNB domain ThiF PF00899.16 CAM69262.1 - 8e-05 22.4 1.2 0.00011 22.0 0.2 1.6 2 0 0 2 2 2 1 ThiF family DUF3356 PF11836.3 CAM69262.1 - 0.01 15.5 0.7 0.061 13.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3356) NADH-u_ox-rdase PF10785.4 CAM69263.1 - 2.2e-17 63.0 2.1 5.8e-17 61.7 1.5 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit PAPS_reduct PF01507.14 CAM69265.1 - 5.2e-24 84.9 0.0 3e-21 75.9 0.0 2.1 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.15 CAM69265.1 - 0.0086 15.5 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 PP-loop family Amelogenin PF02948.10 CAM69267.1 - 0.072 13.7 0.4 0.097 13.2 0.3 1.3 1 0 0 1 1 1 0 Amelogenin zf-CCCH PF00642.19 CAM69268.1 - 2.2e-06 27.1 10.3 5.8e-05 22.6 0.7 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-HIT PF04438.11 CAM69268.1 - 2.4e-06 27.0 10.8 6.3e-06 25.7 7.5 1.7 1 0 0 1 1 1 1 HIT zinc finger zf-CCCH_2 PF14608.1 CAM69268.1 - 0.033 14.2 1.3 0.033 14.2 0.9 2.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type RNB PF00773.14 CAM69271.1 - 1e-92 310.8 0.0 1.6e-92 310.2 0.0 1.2 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 CAM69271.1 - 0.042 13.9 0.1 0.11 12.5 0.1 1.7 1 0 0 1 1 1 0 PIN domain MtN3_slv PF03083.11 CAM69273.2 - 5.1e-19 67.9 11.2 5.7e-11 42.1 2.2 2.4 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Tox-ODYAM1 PF15642.1 CAM69273.2 - 0.0022 16.7 0.1 0.003 16.2 0.1 1.1 1 0 0 1 1 1 1 Toxin in Odyssella and Amoebophilus AAA PF00004.24 CAM69274.1 - 3.6e-40 137.2 0.0 7.7e-40 136.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CAM69274.1 - 1.6e-05 24.0 0.0 3.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Vps4_C PF09336.5 CAM69274.1 - 3.6e-05 23.5 0.2 8.5e-05 22.3 0.2 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 CAM69274.1 - 5.4e-05 23.3 0.1 0.00054 20.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 CAM69274.1 - 0.00017 21.3 0.1 0.11 12.1 0.0 3.1 4 0 0 4 4 4 1 NACHT domain AAA_5 PF07728.9 CAM69274.1 - 0.00034 20.3 0.0 0.002 17.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CAM69274.1 - 0.00049 19.9 0.2 0.0014 18.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 CAM69274.1 - 0.001 18.2 0.1 0.0021 17.2 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 CAM69274.1 - 0.0019 18.9 0.0 0.0053 17.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CAM69274.1 - 0.0037 16.6 0.3 0.24 10.7 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 CAM69274.1 - 0.0045 16.8 0.0 0.013 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 CAM69274.1 - 0.005 16.7 0.0 0.022 14.6 0.0 2.1 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 CAM69274.1 - 0.0051 16.2 0.0 0.014 14.8 0.0 1.6 2 0 0 2 2 2 1 IstB-like ATP binding protein KaiC PF06745.8 CAM69274.1 - 0.0051 15.9 0.1 2.4 7.2 0.0 2.6 2 1 1 3 3 3 2 KaiC AAA_19 PF13245.1 CAM69274.1 - 0.0052 16.5 0.6 0.014 15.1 0.0 2.0 2 0 0 2 2 1 1 Part of AAA domain AAA_24 PF13479.1 CAM69274.1 - 0.0072 15.9 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 CAM69274.1 - 0.0078 14.9 0.0 0.017 13.8 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 CAM69274.1 - 0.0078 16.2 0.0 0.029 14.3 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain Zeta_toxin PF06414.7 CAM69274.1 - 0.011 14.8 0.0 0.025 13.6 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 CAM69274.1 - 0.021 14.9 0.0 0.055 13.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Guanylate_kin PF00625.16 CAM69274.1 - 0.035 13.5 0.0 1.4 8.2 0.0 2.6 3 0 0 3 3 2 0 Guanylate kinase AAA_11 PF13086.1 CAM69274.1 - 0.039 13.5 0.0 0.066 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 CAM69274.1 - 0.051 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 CAM69274.1 - 0.058 12.3 0.0 0.32 9.8 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 CAM69274.1 - 0.059 13.6 0.3 0.32 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 CAM69274.1 - 0.073 11.9 0.0 0.17 10.6 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.11 CAM69274.1 - 0.093 11.9 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Saccharop_dh PF03435.13 CAM69277.1 - 2e-29 102.7 1.3 1.2e-28 100.2 0.4 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 CAM69277.1 - 0.00036 20.5 0.2 0.00058 19.9 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CAM69277.1 - 0.0014 18.0 0.0 0.0028 17.1 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CAM69277.1 - 0.013 14.2 0.0 0.02 13.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 CAM69277.1 - 0.018 15.3 0.0 0.036 14.3 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain TPR_11 PF13414.1 CAM69278.1 - 5.9e-13 48.2 0.6 6.5e-07 28.9 0.1 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 CAM69278.1 - 1.9e-06 27.3 1.9 1.7 8.7 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 CAM69278.1 - 5.2e-06 25.8 2.0 0.41 10.3 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 CAM69278.1 - 1.4e-05 25.6 0.5 0.00036 21.1 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Ecl1 PF12855.2 CAM69278.1 - 0.0062 15.7 2.2 0.016 14.4 1.5 1.8 1 0 0 1 1 1 1 Life-span regulatory factor TPR_12 PF13424.1 CAM69278.1 - 0.01 15.7 1.3 0.94 9.4 0.5 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 CAM69278.1 - 0.02 15.4 0.2 48 4.9 0.1 4.0 2 1 2 4 4 4 0 Tetratricopeptide repeat zf-MYND PF01753.13 CAM69278.1 - 0.14 12.0 13.0 0.42 10.5 9.0 1.9 1 1 0 1 1 1 0 MYND finger TPR_8 PF13181.1 CAM69278.1 - 3 7.8 4.4 97 3.1 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2800 PF10926.3 CAM69279.1 - 0.077 12.0 0.1 0.17 10.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2800) Pkinase PF00069.20 CAM69280.1 - 1.7e-60 204.4 0.0 1.9e-60 204.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM69280.1 - 8.6e-40 136.4 0.0 1.1e-39 136.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM69280.1 - 1e-06 27.9 0.0 1.5e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CAM69280.1 - 0.0043 16.8 1.6 0.037 13.7 0.9 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CAM69280.1 - 0.0057 16.0 0.0 0.0099 15.2 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 CAM69280.1 - 0.013 14.5 0.1 0.026 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 CAM69280.1 - 0.018 13.8 0.0 0.032 13.0 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 CAM69280.1 - 0.086 12.1 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 RIO1 family AAA_23 PF13476.1 CAM69281.1 - 5.2e-22 79.1 0.0 5.2e-22 79.1 0.0 6.4 4 2 0 4 4 2 1 AAA domain SMC_N PF02463.14 CAM69281.1 - 6.5e-15 54.9 0.0 5.3e-07 29.0 0.0 2.6 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 CAM69281.1 - 2.5e-12 46.5 0.0 8.1e-12 44.9 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 CAM69281.1 - 2.3e-09 36.8 1.7 0.0003 19.9 0.0 2.7 3 0 0 3 3 3 2 AAA ATPase domain AAA_21 PF13304.1 CAM69281.1 - 8.1e-09 35.8 0.0 0.0013 18.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CAM69281.1 - 0.00084 18.8 0.0 0.0022 17.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Rad50_zn_hook PF04423.9 CAM69281.1 - 0.0025 17.2 0.1 0.0025 17.2 0.1 3.5 3 0 0 3 3 3 1 Rad50 zinc hook motif ABC_tran PF00005.22 CAM69281.1 - 0.0026 18.0 0.1 0.0026 18.0 0.0 5.9 5 2 1 6 6 6 2 ABC transporter MobB PF03205.9 CAM69281.1 - 0.0063 16.2 0.7 0.51 10.0 0.0 3.7 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 CAM69281.1 - 0.023 14.4 0.5 0.39 10.5 0.0 3.5 2 0 0 2 2 2 0 Part of AAA domain MMR_HSR1 PF01926.18 CAM69281.1 - 0.094 12.6 0.3 1.1 9.2 0.1 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF4440 PF14534.1 CAM69281.1 - 0.22 11.7 5.7 0.23 11.6 0.3 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4440) Ribosomal_S26e PF01283.14 CAM69282.1 - 7.5e-41 138.9 3.6 7.9e-41 138.8 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e zf-CCHC_4 PF14392.1 CAM69282.1 - 0.47 10.1 2.8 0.77 9.4 0.1 2.2 2 0 0 2 2 2 0 Zinc knuckle Rad51 PF08423.6 CAM69283.1 - 9.6e-136 450.6 0.3 1.4e-135 450.1 0.2 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 CAM69283.1 - 9.6e-15 54.4 0.0 1.5e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 CAM69283.1 - 6.6e-09 35.2 0.2 1e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 CAM69283.1 - 6.8e-09 35.7 0.0 1.6e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain KaiC PF06745.8 CAM69283.1 - 1.5e-05 24.2 0.1 3.3e-05 23.1 0.1 1.6 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.1 CAM69283.1 - 0.0086 16.2 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain FLO_LFY PF01698.11 CAM69283.1 - 0.019 13.8 0.1 0.41 9.4 0.0 2.3 2 0 0 2 2 2 0 Floricaula / Leafy protein DnaB_C PF03796.10 CAM69283.1 - 0.021 13.6 0.1 0.045 12.6 0.0 1.5 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain PAXNEB PF05625.6 CAM69283.1 - 0.079 11.7 0.1 0.2 10.4 0.0 1.6 2 0 0 2 2 2 0 PAXNEB protein Mod_r PF07200.8 CAM69284.1 - 1.3e-06 28.3 5.2 1.3e-06 28.3 3.6 1.5 2 0 0 2 2 1 1 Modifier of rudimentary (Mod(r)) protein End3 PF12761.2 CAM69284.1 - 0.00069 19.3 3.4 0.0015 18.2 2.4 1.5 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 Tropomyosin_1 PF12718.2 CAM69284.1 - 0.0031 17.3 2.3 0.0031 17.3 1.6 2.0 2 0 0 2 2 2 1 Tropomyosin like Leu_zip PF15294.1 CAM69284.1 - 0.0033 16.5 2.0 0.0048 16.0 1.4 1.3 1 0 0 1 1 1 1 Leucine zipper Microtub_assoc PF07989.6 CAM69284.1 - 0.01 15.6 1.4 0.027 14.2 0.9 1.7 1 0 0 1 1 1 0 Microtubule associated DUF4337 PF14235.1 CAM69284.1 - 0.014 15.2 0.9 0.014 15.2 0.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) HOOK PF05622.7 CAM69284.1 - 0.015 13.1 8.5 0.037 11.8 5.8 1.5 1 1 0 1 1 1 0 HOOK protein ADIP PF11559.3 CAM69284.1 - 0.023 14.5 6.4 0.074 12.9 4.4 1.9 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Uso1_p115_C PF04871.8 CAM69284.1 - 0.029 14.2 3.0 4.1 7.3 3.8 2.5 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region FlaC_arch PF05377.6 CAM69284.1 - 0.029 14.2 3.4 0.16 11.9 0.9 2.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Adeno_52K PF03052.10 CAM69284.1 - 0.035 13.3 0.8 0.058 12.6 0.5 1.3 1 0 0 1 1 1 0 Adenoviral protein L1 52/55-kDa COG2 PF06148.6 CAM69284.1 - 0.037 13.8 1.8 0.094 12.5 1.2 1.7 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 FliD_C PF07195.7 CAM69284.1 - 0.041 13.1 0.6 0.054 12.7 0.1 1.6 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus BLOC1_2 PF10046.4 CAM69284.1 - 0.047 13.8 1.3 0.12 12.5 0.9 1.7 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TSC22 PF01166.13 CAM69284.1 - 0.058 13.3 3.1 0.13 12.2 1.7 2.0 1 1 0 1 1 1 0 TSC-22/dip/bun family GAS PF13851.1 CAM69284.1 - 0.074 12.2 10.0 0.26 10.4 6.3 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Spc24 PF08286.6 CAM69284.1 - 0.09 12.4 2.7 0.19 11.4 1.8 1.6 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 IncA PF04156.9 CAM69284.1 - 0.13 11.8 7.1 0.027 14.0 2.7 1.6 2 0 0 2 2 1 0 IncA protein NPV_P10 PF05531.7 CAM69284.1 - 0.13 12.5 10.1 0.55 10.5 4.2 3.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein APG6 PF04111.7 CAM69284.1 - 0.13 11.3 6.1 0.14 11.1 3.6 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 Hormone_1 PF00103.15 CAM69284.1 - 0.14 11.5 2.5 0.21 10.8 0.6 2.1 2 1 0 2 2 2 0 Somatotropin hormone family bZIP_1 PF00170.16 CAM69284.1 - 0.15 12.0 1.8 0.34 10.8 0.7 2.1 2 0 0 2 2 1 0 bZIP transcription factor V_ATPase_I PF01496.14 CAM69284.1 - 0.19 9.5 0.7 0.23 9.2 0.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2968 PF11180.3 CAM69284.1 - 0.2 11.0 8.0 0.058 12.7 3.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DivIVA PF05103.8 CAM69284.1 - 0.25 11.4 4.8 0.54 10.3 3.3 1.7 1 1 0 1 1 1 0 DivIVA protein DUF641 PF04859.7 CAM69284.1 - 0.28 10.9 4.4 0.44 10.3 1.8 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) TMF_DNA_bd PF12329.3 CAM69284.1 - 0.46 10.3 6.8 0.29 10.9 2.9 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 CAM69284.1 - 0.51 9.8 8.6 0.057 12.9 1.4 2.6 1 1 2 3 3 3 0 Septum formation initiator Tup_N PF08581.5 CAM69284.1 - 0.51 10.5 6.5 0.42 10.8 2.6 2.2 2 0 0 2 2 2 0 Tup N-terminal Seryl_tRNA_N PF02403.17 CAM69284.1 - 0.63 10.0 4.9 0.82 9.7 1.4 2.3 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Cep57_CLD_2 PF14197.1 CAM69284.1 - 2.6 8.0 9.8 3.4 7.6 3.0 3.0 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 YlqD PF11068.3 CAM69284.1 - 2.9 7.9 9.2 3.2 7.8 4.5 2.1 1 1 1 2 2 2 0 YlqD protein Fib_alpha PF08702.5 CAM69284.1 - 5.1 7.2 11.0 0.8 9.8 2.4 2.9 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF3450 PF11932.3 CAM69284.1 - 7.9 5.6 11.8 1.1 8.4 5.0 1.9 2 1 1 3 3 2 0 Protein of unknown function (DUF3450) Pkinase PF00069.20 CAM69286.1 - 1.1e-56 191.9 0.0 1.5e-37 129.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAM69286.1 - 5.8e-22 78.0 0.0 5.9e-20 71.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CAM69286.1 - 0.0027 17.4 2.4 0.034 13.8 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 CAM69286.1 - 0.0049 15.9 0.0 0.0087 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CAM69286.1 - 0.18 10.7 0.2 14 4.5 0.0 2.4 2 1 0 3 3 3 0 Kinase-like Pox_ser-thr_kin PF05445.6 CAM69286.1 - 0.57 8.9 0.2 1 8.0 0.0 1.4 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Med9 PF07544.8 CAM69287.1 - 0.005 16.5 1.5 0.21 11.3 0.4 2.8 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 SlyX PF04102.7 CAM69287.1 - 0.058 13.7 9.5 4.4 7.7 0.0 3.2 3 0 0 3 3 3 0 SlyX PP1_bind PF15276.1 CAM69287.1 - 0.09 12.8 0.5 1 9.4 0.0 2.9 3 0 0 3 3 3 0 Protein phosphatase 1 binding DUF4618 PF15397.1 CAM69287.1 - 0.12 11.7 2.5 0.19 11.0 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) NPV_P10 PF05531.7 CAM69287.1 - 0.24 11.6 2.0 8.4 6.7 0.3 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein GED PF02212.13 CAM69287.1 - 1.1 9.1 4.1 10 6.1 1.5 2.4 2 0 0 2 2 2 0 Dynamin GTPase effector domain DUF904 PF06005.7 CAM69287.1 - 1.4 9.2 5.6 13 6.1 0.9 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF904) DUF2462 PF09495.5 CAM69288.1 - 7.3 7.3 13.3 10 6.9 7.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2462) Dynein_heavy PF03028.10 CAM69289.1 - 1.4e-219 730.7 0.0 6.5e-219 728.5 0.0 2.1 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 CAM69289.1 - 9.4e-121 403.1 2.6 1.4e-120 402.5 0.1 2.4 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CAM69289.1 - 1.8e-88 295.9 0.1 1.3e-87 293.2 0.0 2.3 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 CAM69289.1 - 8.5e-60 201.9 0.0 5.9e-59 199.2 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 CAM69289.1 - 1.3e-51 174.6 0.6 3.5e-51 173.2 0.4 1.8 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 CAM69289.1 - 2.2e-46 158.2 3.7 2.2e-46 158.2 2.6 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 CAM69289.1 - 5.4e-34 117.5 0.0 1.3e-33 116.2 0.0 1.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 CAM69289.1 - 1.1e-15 57.6 0.1 0.00031 20.4 0.0 6.6 5 2 0 5 5 5 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CAM69289.1 - 1.6e-07 31.4 0.2 1.8 8.6 0.0 5.5 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.17 CAM69289.1 - 1.3e-06 28.5 0.0 0.022 14.9 0.0 4.2 4 0 0 4 4 4 2 RNA helicase AAA PF00004.24 CAM69289.1 - 3.3e-05 24.1 0.3 1.1 9.5 0.0 5.0 5 0 0 5 5 5 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CAM69289.1 - 4.1e-05 23.6 2.3 2.6 7.9 0.0 6.3 7 0 0 7 7 7 1 AAA ATPase domain AAA_17 PF13207.1 CAM69289.1 - 0.00016 22.4 1.9 0.044 14.6 0.0 5.2 5 0 0 5 5 5 1 AAA domain AAA_19 PF13245.1 CAM69289.1 - 0.00061 19.4 3.2 0.88 9.3 0.0 4.4 3 0 0 3 3 3 2 Part of AAA domain Baculo_PEP_C PF04513.7 CAM69289.1 - 0.0017 18.1 4.0 3.1 7.5 0.0 5.2 5 0 0 5 5 5 1 Baculovirus polyhedron envelope protein, PEP, C terminus T2SE PF00437.15 CAM69289.1 - 0.0077 15.1 3.3 0.37 9.6 0.0 4.2 6 0 0 6 6 6 1 Type II/IV secretion system protein AAA_18 PF13238.1 CAM69289.1 - 0.01 16.1 0.0 0.67 10.2 0.0 3.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CAM69289.1 - 0.088 12.2 4.1 7.8 5.8 0.0 4.1 4 0 0 4 4 4 0 AAA domain Mg_chelatase PF01078.16 CAM69289.1 - 0.13 11.4 5.6 0.73 8.9 0.0 4.1 5 0 0 5 5 5 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 CAM69289.1 - 0.15 11.6 0.2 6.6 6.3 0.0 3.2 3 0 0 3 3 3 0 P-loop containing region of AAA domain PhoH PF02562.11 CAM69289.1 - 0.27 10.4 4.0 3.9 6.6 0.0 3.4 3 0 0 3 3 3 0 PhoH-like protein Pkinase PF00069.20 CAM69290.2 - 7e-53 179.4 0.0 1.1e-52 178.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM69290.2 - 1.7e-36 125.6 0.0 2.8e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM69290.2 - 0.075 11.9 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like ER_lumen_recept PF00810.13 CAM69291.1 - 1.1e-51 175.1 9.2 1.9e-51 174.4 6.4 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor ATP_synt_H PF05493.8 CAM69292.1 - 9.1e-21 73.7 6.6 9.7e-21 73.6 4.6 1.0 1 0 0 1 1 1 1 ATP synthase subunit H PspC PF04024.7 CAM69292.1 - 1.2 8.6 5.7 0.22 11.0 1.2 1.7 1 1 1 2 2 2 0 PspC domain DUF4131 PF13567.1 CAM69292.1 - 3.4 7.0 5.2 3.4 7.0 3.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) WD40 PF00400.27 CAM69293.1 - 1.1e-28 98.0 6.3 2.8e-07 30.1 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 CAM69293.1 - 0.02 14.6 0.1 8.2 6.2 0.0 3.1 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region IKI3 PF04762.7 CAM69293.1 - 0.039 11.7 0.0 0.66 7.7 0.0 2.0 2 0 0 2 2 2 0 IKI3 family Ank_2 PF12796.2 CAM69296.1 - 2.9e-20 72.4 3.9 3.8e-15 55.9 0.2 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CAM69296.1 - 3.9e-19 68.2 5.1 3.1e-09 36.7 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 CAM69296.1 - 6.8e-19 67.8 0.7 4.9e-09 36.4 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CAM69296.1 - 3.6e-12 45.2 1.9 0.00012 21.9 0.2 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.25 CAM69296.1 - 5.2e-12 44.9 2.1 0.00021 20.9 0.1 3.7 4 0 0 4 4 4 2 Ankyrin repeat Metallophos PF00149.23 CAM69297.1 - 3.7e-43 147.2 0.2 4.5e-43 146.9 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase BTB_2 PF02214.17 CAM69298.1 - 9.5e-12 44.9 0.0 1.5e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF4539 PF15072.1 CAM69299.1 - 1.5e-17 63.0 0.0 2.3e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) SNARE_assoc PF09335.6 CAM69300.1 - 1.1e-09 38.5 1.1 1.1e-09 38.5 0.7 2.7 2 0 0 2 2 2 1 SNARE associated Golgi protein EF-hand_5 PF13202.1 CAM69300.1 - 0.00015 20.9 0.0 0.00038 19.6 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 CAM69300.1 - 0.0024 17.5 0.0 0.011 15.5 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 CAM69300.1 - 0.007 15.6 0.0 0.025 13.8 0.0 2.0 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 CAM69300.1 - 0.04 14.0 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair Sas10 PF09368.5 CAM69301.1 - 9.2e-21 73.8 4.9 2.5e-20 72.3 3.4 1.8 1 0 0 1 1 1 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 CAM69301.1 - 5e-19 68.2 1.4 1.2e-18 67.0 1.0 1.7 1 0 0 1 1 1 1 Sas10/Utp3/C1D family CagA PF03507.8 CAM69303.1 - 0.015 15.1 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 CagA exotoxin SNF2_N PF00176.18 CAM69305.1 - 3.6e-58 196.7 0.1 7e-58 195.7 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CAM69305.1 - 5.8e-13 48.5 0.0 1.2e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 CAM69305.1 - 1.1e-07 31.7 5.5 2.4e-07 30.6 3.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CAM69305.1 - 4.4e-07 29.4 4.9 9.6e-07 28.3 3.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CAM69305.1 - 1.9e-06 27.4 4.8 3.7e-06 26.4 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAM69305.1 - 1e-05 25.1 6.0 2.4e-05 23.9 4.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CAM69305.1 - 1.1e-05 25.1 5.1 1.1e-05 25.1 3.5 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 CAM69305.1 - 0.00014 21.4 3.8 0.00028 20.5 1.0 2.5 1 1 1 2 2 2 1 RING-type zinc-finger ResIII PF04851.10 CAM69305.1 - 0.00023 21.0 0.2 0.0017 18.2 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit zf-C3HC4_4 PF15227.1 CAM69305.1 - 0.00023 20.9 4.6 0.00047 19.9 3.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-4CXXC_R1 PF10497.4 CAM69305.1 - 0.0061 16.6 5.7 0.017 15.2 3.9 1.7 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 RPE65 PF03055.10 CAM69306.1 - 0.025 13.1 0.0 0.039 12.5 0.0 1.2 1 0 0 1 1 1 0 Retinal pigment epithelial membrane protein PAP_assoc PF03828.14 CAM69307.1 - 2.6e-12 46.4 0.0 5.4e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase DSPc PF00782.15 CAM69308.1 - 1.5e-18 66.6 0.0 2.4e-17 62.7 0.0 2.5 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain EF-hand_7 PF13499.1 CAM69309.1 - 3.8e-15 55.7 0.2 2.4e-06 27.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CAM69309.1 - 3.4e-13 47.8 0.4 4e-05 22.6 0.0 4.0 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 CAM69309.1 - 2.1e-11 43.5 0.0 1.8e-09 37.3 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_6 PF13405.1 CAM69309.1 - 3.5e-10 38.8 2.8 1.6e-05 24.4 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 CAM69309.1 - 1.2e-09 37.5 0.6 0.00012 21.6 0.0 4.1 1 1 3 4 4 4 3 EF-hand domain pair EFhand_Ca_insen PF08726.5 CAM69309.1 - 0.0048 16.8 0.0 0.018 15.0 0.0 1.9 1 1 0 1 1 1 1 Ca2+ insensitive EF hand Caleosin PF05042.8 CAM69309.1 - 0.11 11.9 0.1 19 4.7 0.0 2.8 2 1 1 3 3 3 0 Caleosin related protein DDT PF02791.12 CAM69309.1 - 0.12 12.1 0.4 0.74 9.6 0.0 2.1 2 0 0 2 2 2 0 DDT domain EF-hand_5 PF13202.1 CAM69309.1 - 0.4 10.1 2.0 34 3.9 0.0 3.4 3 0 0 3 3 3 0 EF hand RNA_pol_Rpb8 PF03870.10 CAM69310.1 - 7.5e-27 94.1 0.0 8.5e-27 94.0 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 CSD PF00313.17 CAM69312.1 - 7.2e-16 57.7 0.2 9.5e-16 57.3 0.2 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain RCC1_2 PF13540.1 CAM69312.1 - 0.059 13.0 0.1 0.93 9.2 0.1 2.4 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat DUF1738 PF08401.6 CAM69315.1 - 0.12 12.0 0.0 0.51 10.0 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1738) MCM PF00493.18 CAM69316.1 - 1.9e-129 431.2 0.0 3.1e-129 430.5 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CAM69316.1 - 6.1e-14 52.5 1.9 4.8e-13 49.6 0.2 2.5 2 0 0 2 2 2 1 MCM N-terminal domain MCM2_N PF12619.3 CAM69316.1 - 7.4e-12 45.5 31.8 7.4e-12 45.5 22.1 3.3 3 1 1 4 4 4 1 Mini-chromosome maintenance protein 2 Mg_chelatase PF01078.16 CAM69316.1 - 9.9e-08 31.3 0.0 1e-05 24.7 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CAM69316.1 - 1.9e-05 24.4 0.0 4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CAM69316.1 - 0.0021 17.6 0.0 0.01 15.4 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 CAM69316.1 - 0.033 14.4 0.0 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CAM69316.1 - 0.083 12.3 0.0 0.34 10.3 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain CAP_N PF01213.14 CAM69316.1 - 0.16 11.2 0.1 0.34 10.1 0.1 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Ribonuc_red_lgC PF02867.10 CAM69320.1 - 2.9e-213 709.2 0.0 3.6e-213 708.9 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 CAM69320.1 - 1.7e-23 82.1 0.0 4.6e-23 80.8 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 CAM69320.1 - 2.4e-11 43.9 0.0 7.6e-11 42.3 0.0 1.9 2 0 0 2 2 2 1 ATP cone domain T4SS PF07996.6 CAM69321.1 - 0.021 14.6 9.3 0.2 11.5 0.0 2.3 1 1 1 2 2 2 0 Type IV secretion system proteins DUF4268 PF14088.1 CAM69321.1 - 0.038 13.6 1.9 0.096 12.3 1.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4268) Lebercilin PF15619.1 CAM69321.1 - 0.076 12.4 30.2 2.1 7.7 19.3 2.8 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease AAA_13 PF13166.1 CAM69321.1 - 0.18 10.2 8.0 0.21 10.0 5.5 1.3 1 0 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.7 CAM69321.1 - 0.61 9.9 8.8 0.94 9.3 2.0 2.8 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.5 CAM69321.1 - 0.64 10.1 12.6 0.23 11.5 6.3 2.0 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family CarD_CdnL_TRCF PF02559.11 CAM69321.1 - 1.2 9.2 5.4 0.64 10.0 0.7 2.5 1 1 1 2 2 2 0 CarD-like/TRCF domain Effector_1 PF04518.7 CAM69321.1 - 1.4 7.8 7.9 1.6 7.6 2.7 2.1 1 1 1 2 2 2 0 Effector from type III secretion system T5orf172 PF10544.4 CAM69321.1 - 4.1 7.8 7.0 0.61 10.5 0.9 2.3 1 1 1 2 2 2 0 T5orf172 domain NPV_P10 PF05531.7 CAM69321.1 - 9.1 6.6 11.9 1.4 9.1 1.5 3.1 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Exo_endo_phos PF03372.18 CAM69322.1 - 2.7e-05 24.2 0.0 0.081 12.8 0.0 3.6 3 0 0 3 3 3 3 Endonuclease/Exonuclease/phosphatase family Raptor_N PF14538.1 CAM69323.1 - 0.017 14.9 0.2 0.032 14.0 0.1 1.4 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain ATP_synt_I PF03899.10 CAM69324.1 - 0.074 13.2 0.7 0.42 10.7 0.0 2.3 2 0 0 2 2 2 0 ATP synthase I chain DUF4381 PF14316.1 CAM69324.1 - 0.09 12.8 2.8 0.15 12.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) MAS20 PF02064.10 CAM69324.1 - 0.94 9.4 6.5 0.7 9.8 2.6 2.2 2 0 0 2 2 2 0 MAS20 protein import receptor adh_short PF00106.20 CAM69325.1 - 9.9e-07 28.8 0.1 0.00065 19.6 0.0 2.8 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.1 CAM69325.1 - 0.00031 20.6 0.0 0.38 10.4 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Tctex-1 PF03645.8 CAM69326.1 - 2.2e-25 88.4 0.2 2.6e-25 88.2 0.1 1.0 1 0 0 1 1 1 1 Tctex-1 family Ribosomal_S11 PF00411.14 CAM69327.1 - 7.6e-41 138.7 0.7 9.3e-41 138.4 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF814 PF05670.8 CAM69327.1 - 0.079 12.8 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF814) SM-ATX PF14438.1 CAM69328.1 - 0.00059 19.7 0.1 0.0011 18.8 0.1 1.5 1 1 0 1 1 1 1 Ataxin 2 SM domain LSM PF01423.17 CAM69328.1 - 0.0027 17.2 0.1 0.0032 16.9 0.0 1.4 1 1 0 1 1 1 1 LSM domain MtN3_slv PF03083.11 CAM69329.1 - 0.087 12.6 0.4 0.15 11.9 0.3 1.3 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange Serinc PF03348.10 CAM69330.1 - 7.3e-53 179.8 32.1 5.7e-40 137.3 14.7 2.0 1 1 1 2 2 2 2 Serine incorporator (Serinc) DUF3138 PF11336.3 CAM69333.1 - 5.9 4.9 9.2 1.9 6.5 2.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) FlxA PF14282.1 CAM69333.1 - 6.5 6.7 9.5 0.18 11.7 0.8 2.7 3 0 0 3 3 3 0 FlxA-like protein HMG_box_2 PF09011.5 CAM69337.1 - 0.0013 19.0 1.9 1.1 9.6 0.0 2.8 2 0 0 2 2 2 2 HMG-box domain HGTP_anticodon2 PF12745.2 CAM69337.1 - 0.044 12.9 0.9 0.085 11.9 0.6 1.4 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs DUF1104 PF06518.6 CAM69337.1 - 0.07 13.2 12.9 0.84 9.8 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1104) HMG_box PF00505.14 CAM69337.1 - 0.079 13.2 2.1 11 6.4 0.1 2.8 2 0 0 2 2 2 0 HMG (high mobility group) box ATP-grasp_4 PF13535.1 CAM69338.1 - 5e-25 88.3 0.6 5.6e-17 62.0 0.1 3.4 2 1 1 3 3 3 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 CAM69338.1 - 5.4e-08 31.9 0.0 6e-05 21.9 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 CAM69338.1 - 1.6e-06 28.0 0.1 4.3e-05 23.4 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.12 CAM69338.1 - 8e-05 22.0 0.1 0.0019 17.5 0.0 2.2 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.14 CAM69338.1 - 0.00055 19.5 0.2 0.0014 18.2 0.1 1.6 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.1 CAM69338.1 - 0.014 14.5 0.0 0.16 10.9 0.0 2.1 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp EAP30 PF04157.11 CAM69338.1 - 0.015 14.4 0.8 0.028 13.5 0.6 1.4 1 0 0 1 1 1 0 EAP30/Vps36 family RimK PF08443.6 CAM69338.1 - 0.022 14.2 0.0 0.042 13.3 0.0 1.4 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.8 CAM69338.1 - 0.096 12.0 0.1 0.18 11.1 0.1 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ubiquitin PF00240.18 CAM69340.1 - 2.6e-05 23.5 0.1 5.1e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family WD40 PF00400.27 CAM69341.1 - 1.3e-47 158.0 31.0 2.8e-06 27.0 0.0 10.7 10 0 0 10 10 10 10 WD domain, G-beta repeat eIF2A PF08662.6 CAM69341.1 - 3.3e-06 26.9 0.0 0.18 11.4 0.0 3.4 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 CAM69341.1 - 2.5e-05 23.8 4.5 0.0054 16.2 1.4 3.4 2 1 2 4 4 4 2 PQQ-like domain Gmad1 PF10647.4 CAM69341.1 - 0.00027 20.4 1.5 0.16 11.3 0.1 3.1 4 0 0 4 4 4 2 Lipoprotein LpqB beta-propeller domain PQQ_3 PF13570.1 CAM69341.1 - 0.0036 17.5 10.5 55 4.2 0.0 7.3 6 1 1 7 7 7 0 PQQ-like domain Amastin PF07344.6 CAM69342.1 - 0.0016 18.1 12.3 0.0023 17.5 8.5 1.3 1 0 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.15 CAM69342.1 - 0.034 13.8 9.1 0.057 13.0 6.3 1.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DUF2207 PF09972.4 CAM69342.1 - 0.73 8.3 9.8 8.5 4.8 0.0 2.2 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF4293 PF14126.1 CAM69342.1 - 0.93 9.4 8.8 10 6.0 6.1 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) MLANA PF14991.1 CAM69342.1 - 1.8 8.5 5.5 8 6.5 0.0 2.5 2 1 0 2 2 2 0 Protein melan-A Amastin PF07344.6 CAM69343.1 - 1.6e-33 115.4 21.7 5e-20 71.6 2.9 2.3 2 0 0 2 2 2 2 Amastin surface glycoprotein ETF_alpha PF00766.14 CAM69344.1 - 9.7e-37 124.4 1.8 2e-36 123.4 0.1 2.2 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.16 CAM69344.1 - 1.2e-25 90.1 2.9 1.9e-25 89.4 2.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain PPR_2 PF13041.1 CAM69346.1 - 1.1e-05 25.3 0.3 2 8.4 0.0 5.6 5 1 1 6 6 6 2 PPR repeat family PPR PF01535.15 CAM69346.1 - 0.00013 21.6 2.4 0.066 13.2 0.1 4.8 5 0 0 5 5 5 1 PPR repeat PPR_3 PF13812.1 CAM69346.1 - 0.00035 20.6 8.2 0.21 11.9 0.0 5.6 6 0 0 6 6 6 2 Pentatricopeptide repeat domain AMP-binding PF00501.23 CAM69347.2 - 1.5e-52 178.4 0.1 1.3e-48 165.4 0.0 3.0 3 0 0 3 3 3 3 AMP-binding enzyme AMP-binding_C PF13193.1 CAM69347.2 - 6.3e-09 36.6 0.6 1.7e-08 35.3 0.4 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ATP-synt_C PF00137.16 CAM69348.1 - 3.4e-29 100.5 42.1 3.7e-18 65.1 6.8 3.1 3 0 0 3 3 3 3 ATP synthase subunit C GerA PF03323.8 CAM69348.1 - 0.23 9.5 2.7 3.5 5.6 0.2 2.2 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein ABC2_membrane_5 PF13346.1 CAM69348.1 - 0.28 10.4 4.4 0.17 11.1 0.6 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF2592 PF10766.4 CAM69348.1 - 7.1 6.0 13.8 0.11 11.8 3.9 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2592) LRR_6 PF13516.1 CAM69349.1 - 3.5e-06 26.5 5.5 1.1 9.5 0.0 5.6 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.2 CAM69349.1 - 0.0078 15.8 1.4 1.5 8.5 0.1 4.2 5 0 0 5 5 5 1 Leucine Rich repeats (2 copies) zf-AN1 PF01428.11 CAM69350.1 - 9.6e-09 34.9 8.6 1.5e-08 34.3 6.0 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.10 CAM69350.1 - 0.011 15.8 3.3 0.02 15.0 2.3 1.4 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain DDHD PF02862.12 CAM69350.1 - 0.028 14.1 0.1 0.034 13.9 0.0 1.0 1 0 0 1 1 1 0 DDHD domain DUF4407 PF14362.1 CAM69350.1 - 0.39 9.6 5.0 0.44 9.4 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IBR PF01485.16 CAM69350.1 - 6.9 6.6 9.3 25 4.8 6.3 2.1 1 1 0 1 1 1 0 IBR domain Copine PF07002.11 CAM69352.1 - 1.4e-44 151.3 0.0 2.1e-44 150.8 0.0 1.3 1 0 0 1 1 1 1 Copine C2 PF00168.25 CAM69352.1 - 2.6e-28 97.6 0.1 7.2e-14 51.3 0.1 2.5 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.4 CAM69352.1 - 8.8e-07 28.9 0.0 1.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_2 PF13519.1 CAM69352.1 - 0.00015 21.9 0.0 0.00023 21.3 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain HSP70 PF00012.15 CAM69353.1 - 4.7e-256 850.4 14.2 5.4e-256 850.2 9.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CAM69353.1 - 6.5e-21 74.2 0.8 2.6e-18 65.7 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 CAM69353.1 - 0.0015 18.1 0.0 0.0039 16.8 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 CAM69353.1 - 0.0018 17.4 0.0 0.0018 17.4 0.0 3.1 3 1 1 4 4 4 1 Hydantoinase/oxoprolinase SGL PF08450.7 CAM69356.1 - 9.6e-39 133.2 0.0 5.4e-38 130.7 0.0 2.1 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region FAD_binding_1 PF00667.15 CAM69357.1 - 2.7e-43 147.9 0.0 4.4e-43 147.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CAM69357.1 - 1.4e-34 119.1 0.6 6.8e-34 116.9 0.1 2.2 2 1 1 3 3 3 1 Flavodoxin NAD_binding_1 PF00175.16 CAM69357.1 - 1e-15 58.2 0.0 7.2e-15 55.4 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_NdrI PF07972.6 CAM69357.1 - 0.05 13.5 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 NrdI Flavodoxin like DHDPS PF00701.17 CAM69357.1 - 0.077 11.5 0.0 0.21 10.1 0.0 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate synthetase family APG6 PF04111.7 CAM69358.1 - 0.65 8.9 8.9 1 8.3 6.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 PTPlike_phytase PF14566.1 CAM69358.1 - 1.7 8.7 6.9 3 7.9 4.2 1.8 1 1 1 2 2 2 0 Inositol hexakisphosphate DnaJ PF00226.26 CAM69360.1 - 2.8e-17 62.2 1.0 5e-17 61.4 0.7 1.4 1 0 0 1 1 1 1 DnaJ domain Biopterin_H PF00351.16 CAM69361.1 - 7.2e-123 409.5 0.0 9.4e-123 409.1 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase zf-C3HC4_2 PF13923.1 CAM69363.1 - 2.1e-05 24.4 12.4 3.5e-05 23.7 8.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CAM69363.1 - 2.2e-05 24.0 7.4 3.7e-05 23.3 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CAM69363.1 - 5.2e-05 22.8 9.2 8.8e-05 22.0 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAM69363.1 - 8.3e-05 22.2 7.4 0.00013 21.5 5.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CAM69363.1 - 0.00088 19.0 11.2 0.0015 18.3 7.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 CAM69363.1 - 0.0018 18.1 13.8 0.0029 17.4 9.5 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CAM69363.1 - 0.0063 16.2 5.7 0.013 15.2 3.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 CAM69363.1 - 0.046 13.5 5.9 0.1 12.3 4.1 1.6 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-HIT PF04438.11 CAM69363.1 - 0.11 12.1 4.5 0.12 11.9 0.8 2.1 2 0 0 2 2 2 0 HIT zinc finger Imm22 PF15592.1 CAM69363.1 - 0.13 12.6 0.3 0.27 11.5 0.2 1.5 1 0 0 1 1 1 0 Immunity protein 22 Pup PF05639.6 CAM69363.1 - 0.27 11.7 2.9 2.9 8.4 0.0 2.7 2 0 0 2 2 2 0 Pup-like protein zf-rbx1 PF12678.2 CAM69363.1 - 0.58 10.3 4.1 1.1 9.4 2.8 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C2H2_3 PF13878.1 CAM69363.1 - 0.6 9.7 3.0 0.55 9.8 0.2 2.2 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO CENP-F_leu_zip PF10473.4 CAM69363.1 - 0.93 9.3 15.9 30 4.4 9.7 3.0 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DEAD PF00270.24 CAM69364.1 - 5.7e-39 133.3 0.1 1.9e-38 131.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM69364.1 - 1.7e-21 75.8 0.6 7.3e-21 73.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CAM69364.1 - 1e-14 53.7 0.1 2.3e-14 52.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 CAM69364.1 - 0.0016 18.2 0.0 0.0044 16.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2753 PF10952.3 CAM69364.1 - 0.0047 16.9 0.1 0.0096 15.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2753) DUF3393 PF11873.3 CAM69364.1 - 0.016 14.7 0.1 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3393) UbiA PF01040.13 CAM69365.1 - 4e-27 95.0 17.1 6.1e-27 94.4 11.9 1.4 1 0 0 1 1 1 1 UbiA prenyltransferase family TP2 PF01254.13 CAM69366.1 - 0.34 11.2 6.7 0.36 11.1 3.9 1.6 1 1 0 1 1 1 0 Nuclear transition protein 2 Hydrolase_3 PF08282.7 CAM69367.1 - 5e-21 75.4 0.0 9.4e-20 71.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 CAM69367.1 - 1.2e-05 24.7 0.0 1.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.7 CAM69368.1 - 5.8e-37 127.6 0.0 1.6e-35 122.9 0.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 CAM69368.1 - 1.2e-09 37.8 0.0 7.7e-06 25.3 0.0 2.3 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 CAM69368.1 - 0.0011 19.4 3.5 0.011 16.1 2.4 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CAM69368.1 - 0.0015 18.7 1.2 0.14 12.3 0.8 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CAM69369.1 - 6.6e-52 176.6 0.0 8.6e-52 176.2 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 CAM69369.1 - 3.7e-14 52.6 0.0 2.9e-07 30.0 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 CAM69369.1 - 1.2e-09 38.8 0.1 1.2e-08 35.6 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CAM69369.1 - 5.1e-05 23.5 0.1 0.0073 16.4 0.0 2.5 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 CAM69369.1 - 0.0027 17.5 0.0 0.011 15.6 0.0 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CAM69369.1 - 0.023 14.9 0.4 16 5.6 0.0 3.1 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CAM69370.1 - 2.1e-49 168.4 0.0 2.4e-49 168.1 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 CAM69370.1 - 6.9e-19 68.1 0.0 8.4e-09 35.0 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 CAM69370.1 - 2.1e-06 28.3 0.2 3.7e-05 24.2 0.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CAM69370.1 - 0.0036 17.5 0.5 0.1 12.7 0.0 2.7 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 CAM69370.1 - 0.0076 16.1 0.0 0.053 13.4 0.0 2.3 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CAM69371.1 - 1e-49 169.4 0.0 2.9e-33 115.5 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.8 CAM69371.1 - 2.6e-15 56.4 0.0 5.2e-10 39.0 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 CAM69371.1 - 5e-06 27.0 0.1 0.069 13.5 0.0 2.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 CAM69371.1 - 0.00025 21.2 0.0 0.0032 17.6 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CAM69371.1 - 0.076 13.2 0.1 0.4 10.8 0.0 2.1 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 CAM69371.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Amastin PF07344.6 CAM69372.1 - 3.5e-50 169.6 7.1 4.6e-50 169.2 4.9 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Amastin PF07344.6 CAM69373.1 - 6.9e-34 116.6 7.0 1e-33 116.1 4.8 1.2 1 0 0 1 1 1 1 Amastin surface glycoprotein IMS PF00817.15 CAM69374.1 - 1.8e-34 118.7 0.1 4.9e-34 117.2 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 CAM69374.1 - 2.4e-13 50.1 0.2 6.9e-13 48.6 0.1 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 CAM69374.1 - 9.9e-05 22.1 0.0 0.00024 20.9 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif HHH_5 PF14520.1 CAM69374.1 - 0.051 13.7 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain IMS PF00817.15 CAM69375.1 - 8.8e-39 132.6 0.0 1.6e-38 131.8 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 CAM69375.1 - 1.7e-18 66.7 0.1 3.7e-18 65.6 0.1 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 CAM69375.1 - 0.00034 20.4 0.0 0.0011 18.9 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif zf-Tim10_DDP PF02953.10 CAM69375.1 - 0.12 11.6 0.0 0.29 10.4 0.0 1.6 1 0 0 1 1 1 0 Tim10/DDP family zinc finger Tox-SHH PF15652.1 CAM69375.1 - 0.14 12.7 1.1 0.35 11.4 0.8 1.7 1 0 0 1 1 1 0 HNH/Endo VII superfamily toxin with a SHH signature IMS PF00817.15 CAM69376.1 - 1.4e-21 76.8 0.0 1.4e-20 73.6 0.0 2.2 1 1 0 1 1 1 1 impB/mucB/samB family IMS_HHH PF11798.3 CAM69376.1 - 7.6e-05 22.5 0.0 0.00017 21.4 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif YmaF PF12788.2 CAM69376.1 - 0.069 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 YmaF family TfoX_C PF04994.8 CAM69376.1 - 0.16 11.8 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 TfoX C-terminal domain AAA PF00004.24 CAM69379.1 - 4.5e-30 104.5 0.0 1.8e-21 76.7 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CAM69379.1 - 3.2e-06 26.9 0.0 6.8e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CAM69379.1 - 4e-06 27.6 0.0 1.7e-05 25.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CAM69379.1 - 1.1e-05 25.5 0.0 6.7e-05 23.0 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CAM69379.1 - 1.2e-05 25.1 0.0 2.2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CAM69379.1 - 2.1e-05 23.9 0.0 4.6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 CAM69379.1 - 2.7e-05 23.3 0.0 5.1e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 CAM69379.1 - 9.8e-05 22.2 0.0 0.00036 20.4 0.0 2.1 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 CAM69379.1 - 0.00017 21.6 3.6 0.00087 19.3 0.2 3.6 3 1 0 3 3 2 1 AAA ATPase domain AAA_19 PF13245.1 CAM69379.1 - 0.00038 20.1 0.0 0.0029 17.3 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain TIP49 PF06068.8 CAM69379.1 - 0.0015 17.3 0.0 0.0024 16.6 0.0 1.1 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 CAM69379.1 - 0.0016 17.6 0.1 0.0029 16.8 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.7 CAM69379.1 - 0.0026 17.4 0.0 0.0066 16.1 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_25 PF13481.1 CAM69379.1 - 0.0046 16.3 0.1 0.023 14.1 0.0 2.0 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.17 CAM69379.1 - 0.0063 16.6 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_2 PF07724.9 CAM69379.1 - 0.0076 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_3 PF07726.6 CAM69379.1 - 0.012 15.2 0.0 0.026 14.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 CAM69379.1 - 0.013 14.4 0.0 0.026 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PhoH PF02562.11 CAM69379.1 - 0.02 14.1 0.0 0.038 13.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Zeta_toxin PF06414.7 CAM69379.1 - 0.022 13.8 0.0 0.048 12.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 CAM69379.1 - 0.026 14.4 0.0 0.069 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain SKI PF01202.17 CAM69379.1 - 0.039 13.8 0.0 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase AAA_18 PF13238.1 CAM69379.1 - 0.041 14.1 0.0 0.073 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CAM69379.1 - 0.05 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 ABC transporter DUF2108 PF09881.4 CAM69379.1 - 0.054 13.3 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2108) UPF0079 PF02367.12 CAM69379.1 - 0.06 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 MCM PF00493.18 CAM69379.1 - 0.061 12.1 0.0 0.13 11.0 0.0 1.5 1 0 0 1 1 1 0 MCM2/3/5 family Sigma54_activat PF00158.21 CAM69379.1 - 0.062 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 CAM69379.1 - 0.068 12.8 0.0 11 5.5 0.0 2.2 1 1 1 2 2 2 0 Archaeal ATPase AAA_11 PF13086.1 CAM69379.1 - 0.093 12.2 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 CAM69379.1 - 0.1 12.6 0.0 0.35 10.8 0.0 1.9 2 0 0 2 2 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 CAM69379.1 - 0.23 10.2 0.0 0.37 9.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Syntaxin PF00804.20 CAM69380.1 - 0.001 19.2 3.0 0.001 19.2 2.1 1.9 2 1 0 2 2 2 1 Syntaxin bact-PGI_C PF10432.4 CAM69380.1 - 0.039 13.6 2.3 0.054 13.2 1.5 1.4 1 1 0 1 1 1 0 Bacterial phospho-glucose isomerase C-terminal region PTRF_SDPR PF15237.1 CAM69380.1 - 0.097 12.0 8.5 0.12 11.8 5.9 1.1 1 0 0 1 1 1 0 PTRF/SDPR family Bin3 PF06859.7 CAM69380.1 - 0.13 12.2 0.3 0.23 11.4 0.2 1.4 1 0 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) APG6 PF04111.7 CAM69380.1 - 0.16 11.0 7.8 0.22 10.5 5.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF423 PF04241.10 CAM69382.1 - 2.9e-17 62.3 2.7 4.4e-17 61.7 1.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Claudin_2 PF13903.1 CAM69382.1 - 0.091 12.4 4.1 0.23 11.1 2.8 1.7 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF3017 PF11222.3 CAM69382.1 - 0.74 9.6 5.2 0.28 11.0 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3017) DUF423 PF04241.10 CAM69383.1 - 6.4e-20 70.8 1.2 8.6e-20 70.4 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF423) NADH-u_ox-rdase PF10785.4 CAM69383.1 - 0.013 15.7 0.9 0.022 15.0 0.4 1.5 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit GerA PF03323.8 CAM69383.1 - 0.013 13.6 0.4 0.024 12.7 0.1 1.5 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein DUF3028 PF11229.3 CAM69383.1 - 0.062 11.5 0.0 0.079 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3028) Peptidase_A8 PF01252.13 CAM69383.1 - 0.074 12.6 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Signal peptidase (SPase) II DUF423 PF04241.10 CAM69384.1 - 1.2e-22 79.6 2.5 1.2e-22 79.6 1.7 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF423) DUF95 PF01944.12 CAM69384.1 - 0.7 9.5 6.3 2.7 7.5 0.2 2.1 1 1 1 2 2 2 0 Integral membrane protein DUF95 Reo_sigmaC PF04582.7 CAM69386.1 - 6.2 5.9 23.6 0.84 8.7 0.6 4.3 2 2 2 4 4 4 0 Reovirus sigma C capsid protein DEAD PF00270.24 CAM69387.1 - 5e-42 143.2 0.0 4.3e-40 136.9 0.0 2.1 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM69387.1 - 2.6e-26 91.2 0.1 6e-26 90.1 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 CAM69387.1 - 0.0025 16.9 0.0 0.0061 15.6 0.0 1.6 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.1 CAM69387.1 - 0.0085 15.8 0.8 0.029 14.1 0.0 2.3 2 1 1 3 3 3 1 Part of AAA domain AAA_22 PF13401.1 CAM69387.1 - 0.04 14.0 0.1 0.14 12.2 0.0 1.9 2 1 0 2 2 2 0 AAA domain Coa1 PF08695.5 CAM69389.1 - 0.0041 16.6 0.0 0.013 15.0 0.0 1.8 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 CoA_binding_3 PF13727.1 CAM69389.1 - 0.0089 15.8 0.5 0.013 15.2 0.4 1.2 1 0 0 1 1 1 1 CoA-binding domain IATP PF04568.7 CAM69390.1 - 1 9.4 6.6 2.3 8.3 0.9 2.9 2 1 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Abhydrolase_6 PF12697.2 CAM69391.1 - 1.3e-28 100.4 0.1 1.6e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAM69391.1 - 1.1e-20 74.2 0.0 1.6e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CAM69391.1 - 2.9e-17 62.7 0.0 4.7e-17 62.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CAM69391.1 - 0.00012 21.6 0.0 0.0032 16.9 0.0 2.7 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.5 CAM69391.1 - 0.00013 21.8 0.0 0.00023 20.9 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.16 CAM69391.1 - 0.00027 20.2 0.6 0.028 13.6 0.0 3.0 3 1 1 4 4 4 1 Prolyl oligopeptidase family Ndr PF03096.9 CAM69391.1 - 0.00029 19.4 0.1 0.0014 17.1 0.1 1.8 1 1 0 1 1 1 1 Ndr family FSH1 PF03959.8 CAM69391.1 - 0.0059 16.0 0.0 0.018 14.5 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Peptidase_S15 PF02129.13 CAM69391.1 - 0.006 16.0 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.3 CAM69391.1 - 0.012 15.4 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Esterase_phd PF10503.4 CAM69391.1 - 0.039 13.1 0.4 0.64 9.2 0.2 2.1 1 1 1 2 2 2 0 Esterase PHB depolymerase DLH PF01738.13 CAM69391.1 - 0.053 12.7 0.0 0.92 8.7 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Plasmod_MYXSPDY PF07981.6 CAM69391.1 - 0.075 12.7 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 Plasmodium repeat_MYXSPDY Esterase PF00756.15 CAM69391.1 - 0.092 12.1 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative esterase TPP_enzyme_N PF02776.13 CAM69392.1 - 7.2e-15 54.8 1.1 4.1e-14 52.4 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 CAM69392.1 - 2.1e-10 40.3 3.9 2.4e-09 36.9 0.8 3.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Kelch_3 PF13415.1 CAM69393.1 - 2.5e-17 62.4 2.2 8.2e-07 29.0 0.0 3.8 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_4 PF13418.1 CAM69393.1 - 3e-14 52.5 1.0 4.7e-06 26.2 0.0 3.9 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_5 PF13854.1 CAM69393.1 - 1.1e-13 50.7 0.5 2.4e-06 27.3 0.0 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 CAM69393.1 - 2.2e-13 49.7 0.2 3.1e-05 23.9 0.0 4.5 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 CAM69393.1 - 9.9e-11 40.9 2.9 0.0015 18.2 0.0 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 CAM69393.1 - 8.3e-09 34.8 1.0 0.00069 19.1 0.0 4.3 4 0 0 4 4 4 2 Kelch motif DUF2784 PF10861.3 CAM69393.1 - 0.087 12.6 0.4 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of Unknown function (DUF2784) Helicase_C_2 PF13307.1 CAM69394.1 - 2.5e-44 151.1 0.0 4.4e-44 150.3 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 CAM69394.1 - 1.1e-35 122.6 0.0 1.7e-35 121.9 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.24 CAM69394.1 - 0.00032 20.2 0.0 0.13 11.6 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 CAM69394.1 - 0.00034 20.4 0.0 0.22 11.3 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit TruD PF01142.13 CAM69396.1 - 9.2e-42 143.0 0.0 1.4e-41 142.3 0.0 1.2 1 0 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) DUF3342 PF11822.3 CAM69397.2 - 1.6e-134 447.9 0.0 1.9e-134 447.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) DUF2756 PF10956.3 CAM69398.1 - 0.22 11.8 0.2 0.46 10.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2756) Pkinase PF00069.20 CAM69399.1 - 0.005 16.0 0.0 0.69 9.0 0.0 2.6 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAM69399.1 - 0.19 10.7 0.0 2.5 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein tyrosine kinase Pkinase PF00069.20 CAM69401.1 - 7.8e-64 215.3 0.0 1.1e-63 214.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM69401.1 - 1.7e-33 115.7 0.0 2.7e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Lipocalin_5 PF13924.1 CAM69401.1 - 9.1e-29 99.9 0.0 1.8e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 Lipocalin-like domain PX PF00787.19 CAM69401.1 - 4.4e-14 52.2 0.1 8.8e-14 51.2 0.1 1.5 1 0 0 1 1 1 1 PX domain Kinase-like PF14531.1 CAM69401.1 - 1.4e-05 24.1 0.0 2.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CAM69401.1 - 0.0005 19.8 3.8 0.0064 16.2 0.1 3.1 2 2 1 3 3 3 1 Phosphotransferase enzyme family FYVE PF01363.16 CAM69401.1 - 0.014 15.2 7.6 0.036 13.9 4.9 1.9 1 1 0 1 1 1 0 FYVE zinc finger Sulfate_transp PF00916.15 CAM69402.1 - 1.5e-34 119.2 9.3 2.7e-34 118.4 6.4 1.4 1 0 0 1 1 1 1 Sulfate transporter family His_Phos_2 PF00328.17 CAM69402.1 - 3.4e-15 56.2 0.1 2.2e-13 50.3 0.0 2.5 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) Sulfate_tra_GLY PF13792.1 CAM69402.1 - 2.2e-14 52.8 4.5 6.5e-14 51.3 3.1 1.8 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 CAM69402.1 - 2e-08 33.6 0.0 4e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 STAS domain Amidase_2 PF01510.20 CAM69402.1 - 0.017 15.1 0.0 0.05 13.6 0.0 1.7 1 0 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase PC_rep PF01851.17 CAM69406.1 - 4.3e-15 55.0 9.2 0.053 13.7 0.0 8.6 8 0 0 8 8 8 3 Proteasome/cyclosome repeat HEAT_2 PF13646.1 CAM69406.1 - 7.2e-13 48.6 2.2 3.1e-08 33.7 0.0 4.5 3 1 1 4 4 4 2 HEAT repeats TPR_14 PF13428.1 CAM69406.1 - 0.0021 18.5 0.5 4 8.3 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 CAM69406.1 - 0.012 15.3 2.0 15 5.6 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TIM-br_sig_trns PF09370.5 CAM69406.1 - 0.044 12.8 0.4 0.081 11.9 0.3 1.3 1 0 0 1 1 1 0 TIM-barrel signal transduction protein TPR_2 PF07719.12 CAM69406.1 - 1.7 8.7 8.0 8 6.6 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 CAM69406.1 - 3.2 8.4 9.6 33 5.3 0.0 5.3 5 1 0 5 5 5 0 Tetratricopeptide repeat Nol1_Nop2_Fmu PF01189.12 CAM69407.1 - 1.5e-18 67.1 0.0 1.2e-08 34.6 0.0 2.7 2 1 0 2 2 2 2 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 CAM69407.1 - 0.0065 16.4 0.2 0.023 14.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAM69407.1 - 0.007 16.9 0.1 0.063 13.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain DNA_binding_2 PF13724.1 CAM69407.1 - 0.023 14.8 2.4 0.052 13.7 0.0 2.8 3 0 0 3 3 3 0 DNA-binding domain Methyltransf_30 PF05430.6 CAM69408.1 - 0.0044 16.6 0.0 0.0084 15.7 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-methionine-dependent methyltransferase Effector_1 PF04518.7 CAM69408.1 - 0.26 10.2 0.0 0.43 9.5 0.0 1.2 1 0 0 1 1 1 0 Effector from type III secretion system Pkinase PF00069.20 CAM69409.1 - 2e-13 50.0 0.0 3.8e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 CAM69409.1 - 1.3e-06 28.0 7.9 0.0039 17.0 0.2 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat Pkinase_Tyr PF07714.12 CAM69409.1 - 0.0076 15.3 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 CAM69409.1 - 0.18 11.1 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.1 CAM69409.1 - 0.18 10.7 0.0 0.32 9.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.6 CAM69409.1 - 1.3 7.7 0.0 2 7.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Sporozoite_P67 PF05642.6 CAM69409.1 - 2.8 5.7 7.2 5.1 4.8 5.0 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ArfGap PF01412.13 CAM69410.1 - 2.4e-12 46.6 0.0 3.4e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Topoisom_bac PF01131.15 CAM69411.1 - 1e-100 337.4 0.0 1.3e-100 337.1 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 CAM69411.1 - 2e-15 56.5 0.0 3.4e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Toprim domain Tmem26 PF09772.4 CAM69413.1 - 0.092 11.9 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 26 DUF3597 PF12200.3 CAM69414.1 - 0.16 12.3 2.1 0.28 11.5 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) Rep_fac-A_C PF08646.5 CAM69415.1 - 3.5e-42 143.5 1.0 1.8e-40 138.0 0.1 2.8 3 0 0 3 3 3 1 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 CAM69415.1 - 1.6e-13 50.2 0.5 5.6e-10 38.9 0.0 2.9 3 1 0 3 3 3 2 OB-fold nucleic acid binding domain DZR PF12773.2 CAM69415.1 - 0.052 13.3 2.5 0.098 12.4 1.7 1.4 1 0 0 1 1 1 0 Double zinc ribbon Nairovirus_M PF07948.6 CAM69415.1 - 0.15 10.1 0.3 0.37 8.8 0.0 1.7 2 0 0 2 2 2 0 Nairovirus M polyprotein-like zinc-ribbons_6 PF07191.7 CAM69415.1 - 0.17 11.7 1.7 0.32 10.8 1.2 1.4 1 0 0 1 1 1 0 zinc-ribbons OrfB_Zn_ribbon PF07282.6 CAM69415.1 - 0.71 9.5 2.8 1.5 8.5 1.9 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain SNF2_N PF00176.18 CAM69416.1 - 1.2e-55 188.4 0.0 2.5e-55 187.4 0.0 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 CAM69416.1 - 1e-09 38.0 10.3 1e-09 38.0 7.1 3.6 4 0 0 4 4 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 CAM69416.1 - 2.6e-09 36.9 11.1 2.6e-09 36.9 7.7 3.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.26 CAM69416.1 - 6.1e-09 35.6 0.0 1.7e-08 34.1 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 CAM69416.1 - 7.9e-09 35.0 9.4 7.9e-09 35.0 6.5 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CAM69416.1 - 8.9e-08 31.6 11.2 8.9e-08 31.6 7.8 3.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAM69416.1 - 7.4e-07 28.7 9.4 7.4e-07 28.7 6.5 3.5 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CAM69416.1 - 6.2e-05 22.6 7.3 0.00016 21.3 5.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger ResIII PF04851.10 CAM69416.1 - 0.0002 21.2 0.0 0.00041 20.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_4 PF15227.1 CAM69416.1 - 0.0015 18.3 9.9 0.0015 18.3 6.8 2.5 3 0 0 3 3 1 1 zinc finger of C3HC4-type, RING zf-RanBP PF00641.13 CAM69416.1 - 0.0061 15.6 2.1 0.0061 15.6 1.5 3.3 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others DZR PF12773.2 CAM69416.1 - 0.31 10.8 22.1 0.6 9.9 6.8 3.5 2 1 1 3 3 3 0 Double zinc ribbon Prok-RING_4 PF14447.1 CAM69416.1 - 0.32 10.5 7.3 0.083 12.4 2.5 2.0 2 0 0 2 2 1 0 Prokaryotic RING finger family 4 zf-P11 PF03854.9 CAM69416.1 - 9.7 5.7 13.0 4.4 6.8 3.8 3.2 2 0 0 2 2 2 0 P-11 zinc finger Aldolase_II PF00596.16 CAM69417.1 - 4e-38 130.8 0.0 4.5e-38 130.7 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Kinesin PF00225.18 CAM69418.1 - 4.7e-87 291.8 0.1 7.2e-87 291.2 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain RPA_interact_M PF14767.1 CAM69418.1 - 0.48 11.2 9.6 0.82 10.4 0.1 3.0 2 1 1 3 3 3 0 Replication protein A interacting middle DUF904 PF06005.7 CAM69418.1 - 1.1 9.5 17.3 6.5 7.1 0.7 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF904) DUF4586 PF15239.1 CAM69419.1 - 1.3e-44 153.0 0.9 1.6e-44 152.7 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) Methyltransf_16 PF10294.4 CAM69420.1 - 1.6e-13 50.5 0.5 1.8e-10 40.5 0.2 3.1 2 1 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 CAM69420.1 - 0.00086 19.8 0.0 0.0019 18.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF605 PF04652.11 CAM69420.1 - 0.64 9.3 16.1 1.1 8.5 11.2 1.3 1 0 0 1 1 1 0 Vta1 like DUF663 PF04950.7 CAM69421.1 - 5.4e-74 248.8 0.0 8.6e-74 248.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 CAM69421.1 - 3.7e-24 84.0 0.0 1.3e-23 82.2 0.0 2.0 2 0 0 2 2 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 CAM69421.1 - 0.00013 21.4 0.0 0.0095 15.3 0.0 2.8 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 CAM69421.1 - 0.00013 21.9 0.4 0.00031 20.7 0.0 1.7 2 0 0 2 2 1 1 AAA ATPase domain MobB PF03205.9 CAM69421.1 - 0.00016 21.4 0.2 0.0005 19.7 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 CAM69421.1 - 0.00016 21.8 0.0 0.00041 20.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 CAM69421.1 - 0.002 18.3 0.0 0.0052 16.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 CAM69421.1 - 0.0039 17.1 0.0 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 CAM69421.1 - 0.0064 16.7 0.1 0.049 13.9 0.0 2.4 2 0 0 2 2 2 1 ABC transporter NACHT PF05729.7 CAM69421.1 - 0.0095 15.6 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 CAM69421.1 - 0.01 15.5 0.2 0.033 13.9 0.1 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 CAM69421.1 - 0.015 15.1 2.0 0.022 14.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CAM69421.1 - 0.017 15.9 0.0 0.017 15.9 0.0 3.2 4 0 0 4 4 3 0 AAA domain NTPase_1 PF03266.10 CAM69421.1 - 0.02 14.6 0.1 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_10 PF12846.2 CAM69421.1 - 0.023 14.1 0.5 0.041 13.3 0.0 1.6 2 0 0 2 2 1 0 AAA-like domain ATP_bind_1 PF03029.12 CAM69421.1 - 0.024 14.1 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.9 CAM69421.1 - 0.029 14.1 0.3 0.071 12.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 CAM69421.1 - 0.032 14.5 0.3 0.2 11.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 CAM69421.1 - 0.037 13.4 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 CAM69421.1 - 0.055 13.9 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein NB-ARC PF00931.17 CAM69421.1 - 0.096 11.5 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF258 PF03193.11 CAM69421.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 CAM69421.1 - 0.13 11.8 0.0 0.13 11.8 0.0 2.0 3 0 0 3 3 2 0 Archaeal ATPase AAA_23 PF13476.1 CAM69421.1 - 0.26 11.5 2.9 9.4 6.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain zf-DHHC PF01529.15 CAM69422.1 - 1.4e-28 99.4 1.5 3.3e-28 98.2 1.0 1.7 1 0 0 1 1 1 1 DHHC palmitoyltransferase DnaJ PF00226.26 CAM69423.1 - 1e-08 34.8 0.0 2.2e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain BCIP PF13862.1 CAM69424.1 - 2.9e-21 75.8 0.0 4.2e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 p21-C-terminal region-binding protein dsDNA_bind PF01984.15 CAM69425.1 - 1.4e-22 79.7 13.7 1.5e-22 79.5 9.5 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain UPF0154 PF03672.8 CAM69425.1 - 0.08 12.5 0.1 0.08 12.5 0.0 2.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) NCKAP5 PF15246.1 CAM69425.1 - 0.4 10.0 5.8 0.43 9.9 4.0 1.0 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein DUF1749 PF08538.5 CAM69425.1 - 0.88 8.4 3.9 0.46 9.3 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1749) DUF3408 PF11888.3 CAM69425.1 - 1.7 8.5 5.7 2.5 8.0 2.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3408) DUF2870 PF11069.3 CAM69425.1 - 6.9 6.7 7.7 7.7 6.6 3.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2870) LTXXQ PF07813.7 CAM69425.1 - 9.9 6.6 16.8 8.9 6.8 7.2 2.1 1 1 1 2 2 2 0 LTXXQ motif family protein Zip PF02535.17 CAM69426.1 - 6.8e-37 127.1 13.2 6.8e-37 127.1 9.1 2.4 2 1 0 2 2 2 1 ZIP Zinc transporter CorA PF01544.13 CAM69428.1 - 0.014 14.4 9.4 0.022 13.7 5.8 1.9 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Peptidase_S15 PF02129.13 CAM69429.1 - 1.4e-57 195.1 0.0 5.5e-57 193.2 0.1 1.8 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 CAM69429.1 - 1.5e-33 116.5 0.0 2.2e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 CAM69429.1 - 4.5e-13 49.6 0.5 8.6e-13 48.6 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CAM69429.1 - 3.4e-10 39.8 0.0 4.3e-09 36.2 0.0 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CAM69429.1 - 2.9e-05 23.4 0.9 0.00019 20.7 0.1 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.7 CAM69429.1 - 0.00042 18.9 0.0 0.001 17.6 0.0 1.7 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.15 CAM69429.1 - 0.018 14.5 0.2 0.15 11.6 0.0 2.0 1 1 0 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.13 CAM69429.1 - 0.073 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family GTP_EFTU PF00009.22 CAM69430.1 - 2.1e-39 134.9 0.0 3.9e-39 134.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 CAM69430.1 - 5.7e-20 70.9 0.0 1.2e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 CAM69430.1 - 3.6e-12 45.9 0.1 7.9e-12 44.8 0.1 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CAM69430.1 - 1.8e-05 24.7 0.0 6.2e-05 23.0 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 AIG1 PF04548.11 CAM69430.1 - 0.011 14.8 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 AIG1 family MMR_HSR1 PF01926.18 CAM69430.1 - 0.018 14.9 0.0 0.043 13.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase EFG_IV PF03764.13 CAM69430.1 - 0.034 13.7 0.0 0.15 11.6 0.0 2.1 2 0 0 2 2 2 0 Elongation factor G, domain IV FeoB_N PF02421.13 CAM69430.1 - 0.056 12.7 0.0 0.21 10.8 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B SRPRB PF09439.5 CAM69430.1 - 0.089 12.0 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit LacAB_rpiB PF02502.13 CAM69431.1 - 7.6e-51 171.4 0.5 9.2e-51 171.1 0.4 1.1 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Hanta_G2 PF01561.11 CAM69431.1 - 0.027 12.9 0.2 0.029 12.7 0.1 1.2 1 0 0 1 1 1 0 Hantavirus glycoprotein G2 LRR_6 PF13516.1 CAM69433.1 - 9.7e-20 68.3 1.9 0.081 13.0 0.0 7.7 7 0 0 7 7 7 5 Leucine Rich repeat LRR_4 PF12799.2 CAM69433.1 - 2.2e-08 33.5 4.7 0.028 14.0 0.1 5.3 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CAM69433.1 - 3e-07 29.5 2.9 0.78 10.0 0.0 6.6 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_8 PF13855.1 CAM69433.1 - 0.011 15.4 10.8 0.15 11.7 0.3 4.8 2 2 4 6 6 6 0 Leucine rich repeat GP41 PF00517.12 CAM69433.1 - 0.078 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Retroviral envelope protein LRR_7 PF13504.1 CAM69433.1 - 1.7 9.2 15.6 3.3 8.3 0.0 6.1 7 0 0 7 7 7 0 Leucine rich repeat DuoxA PF10204.4 CAM69434.1 - 0.0066 15.5 1.5 0.0074 15.3 1.0 1.0 1 0 0 1 1 1 1 Dual oxidase maturation factor CobD_Cbib PF03186.8 CAM69434.1 - 0.063 12.3 1.2 0.078 12.0 0.8 1.1 1 0 0 1 1 1 0 CobD/Cbib protein DUF4282 PF14110.1 CAM69434.1 - 0.082 13.1 2.9 0.13 12.4 2.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) DUF2422 PF10337.4 CAM69434.1 - 0.25 10.0 2.8 0.31 9.7 1.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) DUF4131 PF13567.1 CAM69434.1 - 5.2 6.4 6.9 6.8 6.0 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Pkinase PF00069.20 CAM69435.1 - 2.5e-55 187.4 0.0 6.5e-55 186.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM69435.1 - 4.1e-26 91.6 0.0 5.9e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM69435.1 - 0.00029 19.8 0.0 0.0005 19.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CAM69435.1 - 0.0012 18.6 0.0 0.033 13.9 0.0 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CAM69435.1 - 0.074 12.6 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 CAM69435.1 - 0.096 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 CAM69435.1 - 0.12 11.1 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase D123 PF07065.9 CAM69436.1 - 0.062 12.3 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 D123 GRIM-19 PF06212.7 CAM69438.1 - 2.6e-09 36.8 0.0 3.2e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 GRIM-19 protein DPCD PF14913.1 CAM69439.1 - 1.9e-54 183.7 0.0 2.2e-54 183.5 0.0 1.0 1 0 0 1 1 1 1 DPCD protein family AMP-binding PF00501.23 CAM69440.1 - 2e-33 115.4 0.0 4.1e-33 114.3 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme Ank_2 PF12796.2 CAM69440.1 - 3.3e-18 65.7 5.1 5.5e-11 42.6 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CAM69440.1 - 3.6e-15 55.9 0.9 8.7e-09 35.6 0.0 3.4 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 CAM69440.1 - 1.3e-13 49.9 4.8 0.00024 20.7 0.1 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 CAM69440.1 - 8.3e-11 41.0 3.9 0.063 13.5 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 CAM69440.1 - 1.3e-10 41.1 10.8 1.6e-07 31.3 0.2 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) AMP-binding_C PF13193.1 CAM69440.1 - 1.9e-05 25.5 0.0 5.9e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.20 CAM69440.1 - 0.009 16.2 0.0 0.03 14.5 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site RNA_pol_L_2 PF13656.1 CAM69441.1 - 2.1e-23 81.5 0.0 3.1e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 CAM69441.1 - 0.00046 19.2 0.0 0.00083 18.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Gemini_AL1 PF00799.15 CAM69441.1 - 0.059 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain Sua5_yciO_yrdC PF01300.13 CAM69442.1 - 1.8e-46 157.6 0.0 2.5e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 CAM69442.1 - 4e-08 33.3 0.0 6.6e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding DEAD PF00270.24 CAM69443.1 - 8.5e-42 142.5 0.0 1.9e-40 138.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM69443.1 - 4.1e-24 84.2 0.3 9.2e-24 83.1 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAM69443.1 - 7.4e-06 25.9 0.0 1.8e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CAM69443.1 - 0.0052 16.5 0.5 0.023 14.4 0.1 2.4 3 0 0 3 3 3 1 Part of AAA domain T4SS-DNA_transf PF02534.9 CAM69443.1 - 0.0097 14.5 0.0 0.021 13.4 0.0 1.4 2 0 0 2 2 2 1 Type IV secretory system Conjugative DNA transfer PhoH PF02562.11 CAM69443.1 - 0.024 13.8 0.0 4 6.6 0.0 2.9 2 1 1 3 3 3 0 PhoH-like protein CEP76-C2 PF15627.1 CAM69444.1 - 1.1e-42 145.1 0.0 1.9e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 CEP76 C2 domain C2 PF00168.25 CAM69444.1 - 0.012 15.3 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 C2 domain UPF0220 PF05255.6 CAM69445.1 - 7.5e-16 57.8 0.5 8.2e-16 57.6 0.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF4131 PF13567.1 CAM69445.1 - 0.2 11.0 2.4 0.22 10.9 0.0 1.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) SUR7 PF06687.7 CAM69445.1 - 5.3 6.5 6.9 6.6 6.2 3.7 1.8 1 1 1 2 2 2 0 SUR7/PalI family GDPD PF03009.12 CAM69446.1 - 1.5e-20 73.8 0.0 2.4e-17 63.2 0.0 2.1 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family Cullin PF00888.17 CAM69447.1 - 1.6e-43 149.1 4.4 2.3e-43 148.6 3.1 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CAM69447.1 - 9.6e-13 47.7 0.2 6.2e-12 45.1 0.0 2.6 2 0 0 2 2 2 1 Cullin protein neddylation domain Penicillinase_R PF03965.11 CAM69447.1 - 0.0055 16.7 0.0 0.036 14.1 0.0 2.4 2 0 0 2 2 2 1 Penicillinase repressor TrmB PF01978.14 CAM69447.1 - 0.0072 16.0 0.6 0.085 12.5 0.0 2.8 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_27 PF13463.1 CAM69447.1 - 0.14 12.5 0.5 4.7 7.6 0.0 2.9 2 0 0 2 2 2 0 Winged helix DNA-binding domain Cullin PF00888.17 CAM69448.1 - 7.3e-30 104.0 0.0 1.1e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CAM69448.1 - 3.3e-07 30.0 0.9 3.7e-06 26.6 0.1 2.7 3 0 0 3 3 3 1 Cullin protein neddylation domain Penicillinase_R PF03965.11 CAM69448.1 - 0.00032 20.7 0.2 0.0022 18.0 0.0 2.5 2 0 0 2 2 2 1 Penicillinase repressor HTH_27 PF13463.1 CAM69448.1 - 0.0077 16.5 0.1 0.15 12.4 0.0 2.6 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_20 PF12840.2 CAM69448.1 - 0.039 13.7 0.9 7.7 6.3 0.1 3.2 4 0 0 4 4 4 0 Helix-turn-helix domain MarR_2 PF12802.2 CAM69448.1 - 0.053 13.1 0.2 2.6 7.7 0.1 2.8 2 0 0 2 2 2 0 MarR family HTH_DeoR PF08220.7 CAM69448.1 - 0.12 11.9 0.6 1.6 8.3 0.1 2.5 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain Dynein_light PF01221.13 CAM69449.1 - 1.5e-32 111.4 0.0 1.6e-32 111.3 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.13 CAM69449.1 - 0.057 13.7 0.0 0.08 13.2 0.0 1.3 1 1 0 1 1 1 0 Ground-like domain HhH-GPD PF00730.20 CAM69450.1 - 3.4e-19 69.1 0.0 7.5e-18 64.7 0.0 2.7 2 1 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.1 CAM69450.1 - 1.5e-12 46.9 0.0 6.8e-12 44.8 0.0 2.1 2 0 0 2 2 2 1 NUDIX domain HHH PF00633.18 CAM69450.1 - 1.1e-05 24.8 0.1 4.4e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_2 PF12826.2 CAM69450.1 - 0.024 14.5 0.0 5 7.0 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif HHH_5 PF14520.1 CAM69450.1 - 0.061 13.4 0.4 4 7.6 0.0 3.2 3 1 1 4 4 4 0 Helix-hairpin-helix domain Kelch_6 PF13964.1 CAM69451.1 - 2.6e-08 33.6 0.0 0.0016 18.5 0.0 2.7 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 CAM69451.1 - 9.5e-06 25.2 0.1 0.0084 15.8 0.0 3.5 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_3 PF13415.1 CAM69451.1 - 0.00014 21.8 0.1 0.0011 19.1 0.0 2.6 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.10 CAM69451.1 - 0.0013 18.3 0.0 0.0089 15.7 0.0 2.3 2 0 0 2 2 2 1 Kelch motif APS-reductase_C PF12139.3 CAM69451.1 - 0.0025 17.8 0.0 0.0048 17.0 0.0 1.4 1 0 0 1 1 1 1 Adenosine-5'-phosphosulfate reductase beta subunit TOBE_3 PF12857.2 CAM69451.1 - 0.1 12.4 0.1 0.46 10.3 0.0 2.1 2 0 0 2 2 2 0 TOBE-like domain Kelch_1 PF01344.20 CAM69451.1 - 0.11 12.0 0.0 6.5 6.3 0.0 2.5 2 0 0 2 2 2 0 Kelch motif Methyltransf_11 PF08241.7 CAM69452.1 - 4.6e-07 30.2 0.0 8.8e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAM69452.1 - 7.7e-07 29.6 0.0 1.4e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAM69452.1 - 3e-05 23.6 0.0 3.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAM69452.1 - 4.7e-05 23.7 0.0 8.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 CAM69452.1 - 0.013 15.0 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 FUSC PF04632.7 CAM69453.2 - 0.052 11.9 0.0 0.066 11.6 0.0 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Mnd1 PF03962.10 CAM69453.2 - 0.059 13.0 3.1 0.092 12.3 2.2 1.2 1 0 0 1 1 1 0 Mnd1 family CorA PF01544.13 CAM69453.2 - 0.1 11.6 0.4 0.35 9.8 0.7 1.5 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF4407 PF14362.1 CAM69453.2 - 0.2 10.6 4.6 0.29 10.0 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Prefoldin_2 PF01920.15 CAM69453.2 - 0.26 11.0 6.0 1.8 8.3 0.8 2.4 2 0 0 2 2 2 0 Prefoldin subunit TBPIP PF07106.8 CAM69453.2 - 0.41 10.1 6.3 0.43 10.1 3.2 1.8 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spc24 PF08286.6 CAM69453.2 - 1.6 8.4 5.5 2.4 7.8 2.5 2.1 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Snf7 PF03357.16 CAM69453.2 - 4.8 6.5 10.8 2.4 7.5 0.4 2.3 1 1 0 2 2 2 0 Snf7 bZIP_1 PF00170.16 CAM69455.1 - 0.021 14.7 5.0 0.82 9.6 0.4 2.8 2 0 0 2 2 2 0 bZIP transcription factor Prp19 PF08606.6 CAM69455.1 - 0.027 14.1 0.2 0.027 14.1 0.1 2.3 2 0 0 2 2 2 0 Prp19/Pso4-like LsmAD PF06741.8 CAM69455.1 - 0.1 12.6 5.4 1.9 8.6 0.3 2.5 2 0 0 2 2 2 0 LsmAD domain Mnd1 PF03962.10 CAM69455.1 - 0.61 9.7 12.3 1.6 8.3 2.2 2.4 2 0 0 2 2 2 0 Mnd1 family GrpE PF01025.14 CAM69455.1 - 8.7 5.8 9.5 1.2 8.6 1.0 2.5 2 0 0 2 2 2 0 GrpE Glyco_hydro_63 PF03200.11 CAM69456.1 - 1.1e-63 215.3 0.0 1.2e-49 168.9 0.0 2.1 1 1 1 2 2 2 2 Mannosyl oligosaccharide glucosidase Ribosomal_S14 PF00253.16 CAM69457.1 - 2.3e-16 58.9 3.4 2.4e-16 58.8 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Ribosomal_L40e PF01020.12 CAM69457.1 - 0.052 13.1 2.2 0.42 10.2 0.5 2.2 2 0 0 2 2 2 0 Ribosomal L40e family PhosphMutase PF10143.4 CAM69459.1 - 6.2e-60 201.7 0.0 1.1e-59 200.9 0.0 1.4 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.13 CAM69459.1 - 4.4e-16 59.0 0.0 7.1e-15 55.0 0.0 2.4 2 1 0 2 2 2 1 Metalloenzyme superfamily AIG2 PF06094.7 CAM69459.1 - 1.6e-10 41.4 0.0 4.8e-10 39.8 0.0 2.0 1 0 0 1 1 1 1 AIG2-like family Cyclin_N PF00134.18 CAM69460.2 - 0.0004 19.9 0.2 0.00079 18.9 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Type_III_YscX PF09474.5 CAM69460.2 - 0.061 13.3 0.1 0.41 10.6 0.0 2.1 2 0 0 2 2 2 0 Type III secretion system YscX (type_III_YscX) PEX11 PF05648.9 CAM69463.1 - 6.2e-06 25.6 3.4 1.7e-05 24.2 2.4 1.7 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PEX11 PF05648.9 CAM69464.1 - 1.7e-21 76.5 0.4 2.7e-21 75.9 0.3 1.3 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) MOZ_SAS PF01853.13 CAM69465.1 - 2.4e-36 124.7 0.2 2.3e-20 72.6 0.3 2.9 3 0 0 3 3 3 2 MOZ/SAS family DNA_topoisoIV PF00521.15 CAM69466.2 - 8.7e-130 433.3 0.0 1.4e-129 432.7 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 CAM69466.2 - 1.4e-29 102.5 0.1 3.5e-29 101.2 0.0 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.21 CAM69466.2 - 5e-10 39.0 0.0 1.6e-09 37.4 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.17 CAM69466.2 - 1.1e-08 34.9 0.0 3.1e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 Toprim domain Hexapep PF00132.19 CAM69467.1 - 2.2e-07 30.0 5.6 4.7e-05 22.6 0.5 3.9 1 1 4 5 5 5 5 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CAM69467.1 - 0.0025 17.3 5.9 0.067 12.7 0.2 3.5 1 1 2 3 3 3 1 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.18 CAM69467.1 - 0.026 13.8 0.0 0.11 11.7 0.0 1.8 2 0 0 2 2 2 0 Nucleotidyl transferase NTP_transf_3 PF12804.2 CAM69467.1 - 0.061 13.3 0.1 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 MobA-like NTP transferase domain SR-25 PF10500.4 CAM69467.1 - 8.5 5.7 15.0 0.51 9.7 3.9 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Cep57_MT_bd PF06657.8 CAM69468.1 - 0.0005 19.9 2.9 0.12 12.3 0.0 2.8 2 0 0 2 2 2 2 Centrosome microtubule-binding domain of Cep57 Mnd1 PF03962.10 CAM69468.1 - 0.17 11.5 2.0 1.1 8.8 0.3 2.1 2 0 0 2 2 2 0 Mnd1 family Seryl_tRNA_N PF02403.17 CAM69468.1 - 1.1 9.2 2.8 2.7 8.0 0.6 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 PF07926.7 CAM69468.1 - 1.7 8.4 6.3 1.4 8.6 0.1 2.5 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein eIF3_N PF09440.5 CAM69469.1 - 9.4e-29 100.2 2.2 1.9e-28 99.2 1.5 1.5 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 CAM69469.1 - 2.7e-09 37.2 0.5 8.7e-09 35.6 0.3 2.0 2 0 0 2 2 2 1 PCI domain TPR_3 PF07720.7 CAM69469.1 - 0.076 12.8 1.5 0.21 11.4 1.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat CactinC_cactus PF09732.4 CAM69471.1 - 9.7e-40 135.0 1.4 1.6e-39 134.3 1.0 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein SHMT PF00464.14 CAM69474.1 - 3.3e-173 575.6 0.0 4.2e-173 575.3 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 CAM69474.1 - 0.0047 16.1 0.0 0.0069 15.5 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase MCM PF00493.18 CAM69476.1 - 3.1e-120 400.9 0.4 4.5e-120 400.4 0.2 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CAM69476.1 - 3.6e-08 33.9 0.0 8.7e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 CAM69476.1 - 2.1e-07 30.3 0.0 3.6e-06 26.2 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CAM69476.1 - 0.00042 20.0 0.2 0.0033 17.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 CAM69476.1 - 0.0053 16.2 0.1 0.018 14.5 0.1 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 CAM69476.1 - 0.0084 15.7 0.0 0.022 14.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF188 PF02639.9 CAM69476.1 - 0.11 11.9 1.1 7.9 5.9 0.1 2.6 2 1 0 2 2 2 0 Uncharacterized BCR, YaiI/YqxD family COG1671 QRPTase_C PF01729.14 CAM69476.1 - 0.23 10.9 3.4 0.46 9.9 0.2 2.7 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, C-terminal domain WW PF00397.21 CAM69477.1 - 1.9e-09 37.1 0.7 4e-09 36.1 0.5 1.6 1 0 0 1 1 1 1 WW domain GCD14 PF08704.5 CAM69478.1 - 2.1e-62 210.8 2.1 6.1e-58 196.2 0.1 3.3 2 1 1 3 3 3 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 CAM69478.1 - 9.4e-10 38.2 0.0 1.9e-09 37.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CAM69478.1 - 5.9e-06 26.3 1.7 1.5e-05 24.9 0.7 2.1 2 1 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 CAM69478.1 - 4.1e-05 23.2 0.0 0.00012 21.6 0.0 1.8 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.7 CAM69478.1 - 0.00025 21.4 0.0 0.0019 18.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 CAM69478.1 - 0.0025 18.6 0.1 0.0073 17.1 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAM69478.1 - 0.0034 17.9 0.0 0.0079 16.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Fibrillarin PF01269.12 CAM69478.1 - 0.0056 15.6 0.0 0.67 8.8 0.0 2.3 2 0 0 2 2 2 1 Fibrillarin MTS PF05175.9 CAM69478.1 - 0.0059 15.9 0.0 0.026 13.8 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase small domain Ubie_methyltran PF01209.13 CAM69478.1 - 0.0082 15.2 0.0 0.13 11.3 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 CAM69478.1 - 0.012 16.0 0.2 0.18 12.3 0.0 2.6 2 1 0 2 2 1 0 Methyltransferase domain RrnaAD PF00398.15 CAM69478.1 - 0.021 13.8 0.0 0.037 13.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Rft-1 PF04506.8 CAM69479.1 - 1.2e-22 80.0 11.3 1.8e-21 76.1 1.6 2.8 3 0 0 3 3 3 2 Rft protein 2-oxoacid_dh PF00198.18 CAM69480.1 - 9.3e-81 270.4 0.3 1.2e-80 270.1 0.2 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CAM69480.1 - 2.3e-20 72.0 1.8 3.9e-20 71.2 1.2 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 CAM69480.1 - 8e-06 25.4 0.4 0.034 13.8 0.1 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like GCV_H PF01597.14 CAM69480.1 - 0.00042 20.0 0.8 0.0008 19.0 0.6 1.4 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD PF00529.15 CAM69480.1 - 0.00073 18.9 0.8 0.0049 16.2 0.1 2.1 1 1 1 2 2 2 1 HlyD family secretion protein HlyD_3 PF13437.1 CAM69480.1 - 0.0075 16.5 0.6 0.37 11.1 0.1 2.4 1 1 1 2 2 2 1 HlyD family secretion protein HlyD_2 PF12700.2 CAM69480.1 - 0.011 14.9 0.1 0.55 9.3 0.0 2.3 1 1 1 2 2 2 0 HlyD family secretion protein Hc1 PF07432.8 CAM69480.1 - 0.2 11.8 9.3 0.4 10.8 6.5 1.5 1 0 0 1 1 1 0 Histone H1-like protein Hc1 DUF3275 PF11679.3 CAM69480.1 - 0.32 10.6 2.1 0.49 10.0 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) ATP-synt_ab PF00006.20 CAM69481.1 - 4.6e-61 206.0 0.0 5.9e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CAM69481.1 - 1.7e-15 57.4 0.0 3.4e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CAM69481.1 - 1.3e-13 50.9 1.4 2.5e-13 50.0 1.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Hexapep PF00132.19 CAM69482.1 - 0.00012 21.3 11.8 0.036 13.5 2.9 3.7 2 1 2 4 4 4 2 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 CAM69482.1 - 0.00028 20.2 0.0 0.00073 18.9 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 CAM69482.1 - 0.0082 16.2 0.0 0.084 12.9 0.0 2.4 1 1 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.7 CAM69482.1 - 0.11 10.9 0.2 0.19 10.2 0.2 1.3 1 0 0 1 1 1 0 L-fucokinase Hexapep_2 PF14602.1 CAM69482.1 - 1.7 8.2 9.3 1.8e+02 1.7 5.3 3.6 2 1 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase DUF676 PF05057.9 CAM69483.1 - 4.7e-14 52.1 0.0 6.6e-13 48.4 0.0 2.4 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 CAM69483.1 - 0.093 12.3 0.0 0.18 11.3 0.0 1.7 1 1 0 1 1 1 0 PGAP1-like protein FG-GAP PF01839.18 CAM69484.1 - 3.7e-07 29.6 4.5 0.0016 18.1 0.0 5.0 5 0 0 5 5 5 3 FG-GAP repeat VCBS PF13517.1 CAM69484.1 - 9.7e-07 29.0 0.0 0.8 10.1 0.0 5.3 6 0 0 6 6 6 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Ribosomal_S14 PF00253.16 CAM69485.1 - 2.3e-16 58.9 3.4 2.4e-16 58.8 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Ribosomal_L40e PF01020.12 CAM69485.1 - 0.052 13.1 2.2 0.42 10.2 0.5 2.2 2 0 0 2 2 2 0 Ribosomal L40e family ParA PF10609.4 CAM69486.1 - 2e-35 120.4 0.1 3.8e-35 119.6 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 CAM69486.1 - 5e-18 65.1 0.0 6.9e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 CAM69486.1 - 1.4e-08 34.1 1.0 8.4e-08 31.6 0.7 1.9 1 1 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.1 CAM69486.1 - 2.4e-07 30.7 0.1 7.7e-07 29.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 CAM69486.1 - 3.4e-05 23.1 0.0 0.00049 19.3 0.1 2.1 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.6 CAM69486.1 - 4.9e-05 22.5 0.2 0.0001 21.4 0.0 1.5 2 0 0 2 2 2 1 VirC1 protein ArsA_ATPase PF02374.10 CAM69486.1 - 0.00013 21.1 0.5 0.0016 17.5 0.4 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase YhjQ PF06564.7 CAM69486.1 - 0.047 13.0 0.3 0.3 10.3 0.1 1.9 2 0 0 2 2 2 0 YhjQ protein DUF1611 PF07755.6 CAM69486.1 - 0.26 9.9 1.2 0.38 9.3 0.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1611) IF4E PF01652.13 CAM69489.1 - 1.4e-30 106.0 0.0 1.9e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E MRP-L20 PF12824.2 CAM69489.1 - 0.03 14.2 1.1 0.061 13.2 0.7 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 Acyl-CoA_dh_C PF12806.2 CAM69490.1 - 5.9e-25 87.6 1.7 1.2e-24 86.6 1.2 1.5 1 0 0 1 1 1 1 Acetyl-CoA dehydrogenase C-terminal like Acyl-CoA_dh_1 PF00441.19 CAM69490.1 - 4.8e-18 65.6 4.0 6.1e-17 62.1 2.7 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CAM69490.1 - 1.4e-15 56.5 0.0 3.4e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 CAM69490.1 - 2.1e-11 44.4 0.0 5.3e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 CAM69490.1 - 4.7e-07 30.1 0.2 1.5e-06 28.5 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain R3H PF01424.17 CAM69491.1 - 2.3e-10 39.9 0.3 5.3e-10 38.8 0.2 1.7 1 0 0 1 1 1 1 R3H domain BUD22 PF09073.5 CAM69491.1 - 0.02 13.9 1.8 0.047 12.7 1.2 1.6 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.9 CAM69491.1 - 2.1 6.2 6.7 0.3 9.0 1.3 1.8 2 0 0 2 2 2 0 CDC45-like protein PIF1 PF05970.9 CAM69492.1 - 1.4e-29 103.1 0.2 1.4e-25 90.0 0.0 3.3 4 0 0 4 4 4 2 PIF1-like helicase AAA_30 PF13604.1 CAM69492.1 - 4e-11 42.8 0.6 1.1e-10 41.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.1 CAM69492.1 - 2.7e-05 24.2 0.0 6.3e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 CAM69492.1 - 6.2e-05 22.6 0.3 6.2e-05 22.6 0.2 3.4 3 0 0 3 3 3 1 Part of AAA domain Viral_helicase1 PF01443.13 CAM69492.1 - 9.3e-05 22.0 0.0 0.26 10.7 0.0 2.6 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase MobB PF03205.9 CAM69492.1 - 0.012 15.3 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 CAM69492.1 - 0.027 14.4 1.2 0.093 12.7 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain Pox_A32 PF04665.7 CAM69492.1 - 0.099 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein DUF2075 PF09848.4 CAM69492.1 - 0.1 11.5 0.0 0.27 10.1 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 CAM69492.1 - 0.13 11.4 0.0 0.28 10.3 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Herpes_Helicase PF02689.9 CAM69492.1 - 0.21 9.2 0.7 6.7 4.3 0.0 2.1 2 0 0 2 2 2 0 Helicase IstB_IS21 PF01695.12 CAM69492.1 - 0.25 10.7 1.8 0.33 10.3 0.3 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein HEAT_2 PF13646.1 CAM69493.1 - 7.5e-09 35.7 20.1 0.00047 20.3 1.1 7.1 6 1 0 6 6 6 3 HEAT repeats HEAT PF02985.17 CAM69493.1 - 0.00022 21.0 17.0 0.22 11.6 0.0 7.0 7 1 1 8 8 8 3 HEAT repeat TPR_2 PF07719.12 CAM69494.1 - 1e-06 28.1 0.2 0.024 14.5 0.2 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 CAM69494.1 - 3.9e-05 23.2 0.3 0.00022 20.8 0.1 2.4 2 1 0 2 2 2 1 TPR repeat zf-MYND PF01753.13 CAM69494.1 - 0.0028 17.4 8.4 0.0028 17.4 5.8 2.3 2 0 0 2 2 2 1 MYND finger TPR_12 PF13424.1 CAM69494.1 - 0.0058 16.5 0.5 0.044 13.7 0.1 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CAM69494.1 - 0.049 14.2 1.8 4.4 8.2 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 CAM69494.1 - 0.055 13.1 0.0 4.4 7.0 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 CAM69494.1 - 0.098 13.3 0.3 0.098 13.3 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CAM69494.1 - 0.12 12.9 0.0 20 5.8 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_S17e PF00833.13 CAM69495.1 - 5.5e-51 171.4 3.5 7e-51 171.0 2.4 1.1 1 0 0 1 1 1 1 Ribosomal S17 Ribosomal_S17e PF00833.13 CAM69496.1 - 5.5e-51 171.4 3.5 7e-51 171.0 2.4 1.1 1 0 0 1 1 1 1 Ribosomal S17 HEAT_2 PF13646.1 CAM69498.1 - 3.3e-13 49.7 20.1 0.0013 18.9 2.7 7.0 3 2 2 6 6 6 3 HEAT repeats SF3b1 PF08920.5 CAM69498.1 - 1.4e-08 34.8 0.0 2.8e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Splicing factor 3B subunit 1 UME PF08064.8 CAM69498.1 - 2.2e-05 24.3 1.8 0.0071 16.2 0.0 4.2 5 0 0 5 5 5 1 UME (NUC010) domain HEAT_EZ PF13513.1 CAM69498.1 - 0.0033 17.8 21.2 15 6.2 1.8 8.2 7 2 2 9 9 9 0 HEAT-like repeat MMS19_C PF12460.3 CAM69498.1 - 0.0059 15.3 0.1 0.57 8.8 0.0 3.4 3 1 0 3 3 3 1 RNAPII transcription regulator C-terminal RIX1 PF08167.7 CAM69498.1 - 0.0094 15.6 0.0 2 8.0 0.0 3.4 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis Adaptin_N PF01602.15 CAM69498.1 - 0.011 14.0 0.8 2.7 6.1 0.1 2.8 2 1 0 2 2 2 0 Adaptin N terminal region NUC173 PF08161.7 CAM69498.1 - 0.02 14.2 0.3 0.69 9.2 0.0 3.3 4 0 0 4 4 4 0 NUC173 domain CTD PF12815.2 CAM69498.1 - 0.026 14.9 3.0 0.047 14.1 2.1 1.3 1 0 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 HEAT PF02985.17 CAM69498.1 - 0.049 13.7 16.9 1.6 8.9 0.0 7.3 9 0 0 9 9 8 0 HEAT repeat DHO_dh PF01180.16 CAM69498.1 - 0.11 11.4 0.1 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase IQ PF00612.22 CAM69499.1 - 8.3e-10 37.4 10.6 1.3e-05 24.3 2.0 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif LRR_4 PF12799.2 CAM69499.1 - 5.3e-09 35.4 6.5 0.00016 21.2 0.1 3.6 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM69499.1 - 4.5e-08 32.7 8.4 0.00011 21.9 0.0 3.2 2 1 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 CAM69499.1 - 8.9e-05 22.0 8.5 1.2 9.4 0.1 5.8 5 1 0 5 5 5 1 Leucine Rich Repeat LRR_7 PF13504.1 CAM69499.1 - 0.0018 18.1 6.5 8.2 7.1 0.0 5.6 5 0 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 CAM69499.1 - 0.0072 16.2 8.5 14 6.0 0.0 5.0 5 0 0 5 5 5 1 Leucine Rich repeat ADP_ribosyl_GH PF03747.9 CAM69500.1 - 6.4e-12 45.8 0.2 1.1e-07 31.9 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylglycohydrolase IQ PF00612.22 CAM69501.1 - 3.3e-19 66.6 91.3 0.0015 17.9 0.1 14.3 14 0 0 14 14 14 11 IQ calmodulin-binding motif Fis1_TPR_C PF14853.1 CAM69501.1 - 0.018 14.8 0.0 0.043 13.6 0.0 1.6 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Adaptin_N PF01602.15 CAM69502.1 - 4.8e-71 239.6 10.3 5.9e-71 239.3 7.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 CAM69502.1 - 3.2e-37 127.6 0.0 7e-37 126.5 0.0 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 CAM69502.1 - 1.5e-08 34.8 5.7 0.17 12.1 0.2 5.0 3 1 2 5 5 5 4 HEAT repeats HEAT PF02985.17 CAM69502.1 - 1.3e-05 24.8 5.1 8.2 6.8 0.1 6.3 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 CAM69502.1 - 4.1 8.0 7.2 22 5.6 0.8 4.0 3 0 0 3 3 3 0 HEAT-like repeat MoaC PF01967.16 CAM69504.1 - 9.9e-20 70.5 0.0 9.6e-19 67.3 0.0 2.4 1 1 0 1 1 1 1 MoaC family ECIST_Cterm PF14784.1 CAM69504.1 - 0.39 10.6 1.8 0.87 9.5 1.2 1.6 1 0 0 1 1 1 0 C-terminal domain of the ECSIT protein His_Phos_2 PF00328.17 CAM69505.1 - 6.1e-20 71.8 0.0 2.1e-12 47.0 0.2 2.9 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) SelR PF01641.13 CAM69506.1 - 1.3e-39 134.6 0.0 1.6e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 SelR domain DUF2296 PF10058.4 CAM69506.1 - 0.0034 17.0 0.2 0.19 11.4 0.0 2.4 2 0 0 2 2 2 1 Predicted integral membrane metal-binding protein (DUF2296) HNH_5 PF14279.1 CAM69506.1 - 0.026 14.5 0.1 0.17 11.8 0.0 2.1 2 0 0 2 2 2 0 HNH endonuclease TF_Zn_Ribbon PF08271.7 CAM69506.1 - 0.029 13.7 2.8 0.32 10.3 0.1 2.9 3 0 0 3 3 3 0 TFIIB zinc-binding Endonuclease_7 PF02945.10 CAM69506.1 - 0.11 12.2 1.9 0.54 9.9 1.3 2.1 1 1 0 1 1 1 0 Recombination endonuclease VII Yippee-Mis18 PF03226.9 CAM69506.1 - 0.14 12.2 2.6 0.96 9.5 0.0 2.3 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DZR PF12773.2 CAM69506.1 - 1.3 8.9 5.5 5.1 6.9 0.3 2.4 2 1 0 2 2 2 0 Double zinc ribbon Metallophos PF00149.23 CAM69507.1 - 1.7e-39 135.3 0.2 2.1e-39 135.0 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase VitD-bind_III PF09164.5 CAM69507.1 - 0.0035 16.9 0.6 0.0088 15.6 0.4 1.6 1 0 0 1 1 1 1 Vitamin D binding protein, domain III COX15-CtaA PF02628.10 CAM69508.1 - 9.7e-87 290.6 13.6 1.1e-86 290.3 9.4 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein 2OG-FeII_Oxy_2 PF13532.1 CAM69511.1 - 7.4e-05 22.6 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Toprim_C_rpt PF13368.1 CAM69512.1 - 0.081 13.4 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Topoisomerase C-terminal repeat APG12 PF04110.8 CAM69512.1 - 0.099 12.8 0.0 0.77 9.9 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF179 PF02622.10 CAM69513.1 - 4.5e-05 23.1 0.0 0.0001 21.9 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 WD40 PF00400.27 CAM69514.2 - 3.6e-59 194.6 26.5 2.6e-11 42.9 1.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CAM69514.2 - 3.5e-08 32.0 5.9 0.0042 15.2 0.2 3.7 1 1 3 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.6 CAM69514.2 - 1.4e-07 31.4 0.0 0.0002 21.1 0.0 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 CAM69514.2 - 6.1e-05 21.9 0.5 0.39 9.4 0.1 3.6 1 1 1 2 2 2 2 Nup133 N terminal like PQQ_2 PF13360.1 CAM69514.2 - 0.00096 18.6 0.2 0.092 12.1 0.0 2.2 1 1 1 2 2 1 1 PQQ-like domain Cytochrom_D1 PF02239.11 CAM69514.2 - 0.019 13.3 0.0 0.88 7.8 0.0 2.5 1 1 1 3 3 3 0 Cytochrome D1 heme domain PD40 PF07676.7 CAM69514.2 - 0.035 13.7 0.7 6.4 6.5 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF3312 PF11768.3 CAM69514.2 - 0.17 10.1 0.0 0.51 8.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) WD40 PF00400.27 CAM69516.2 - 3.6e-59 194.6 26.5 2.6e-11 42.9 1.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CAM69516.2 - 3.5e-08 32.0 5.9 0.0042 15.2 0.2 3.7 1 1 3 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.6 CAM69516.2 - 1.4e-07 31.4 0.0 0.0002 21.1 0.0 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 CAM69516.2 - 6.1e-05 21.9 0.5 0.39 9.4 0.1 3.6 1 1 1 2 2 2 2 Nup133 N terminal like PQQ_2 PF13360.1 CAM69516.2 - 0.00096 18.6 0.2 0.092 12.1 0.0 2.2 1 1 1 2 2 1 1 PQQ-like domain Cytochrom_D1 PF02239.11 CAM69516.2 - 0.019 13.3 0.0 0.88 7.8 0.0 2.5 1 1 1 3 3 3 0 Cytochrome D1 heme domain PD40 PF07676.7 CAM69516.2 - 0.035 13.7 0.7 6.4 6.5 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF3312 PF11768.3 CAM69516.2 - 0.17 10.1 0.0 0.51 8.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Spc97_Spc98 PF04130.8 CAM69517.1 - 3.9e-58 197.1 0.1 6.9e-58 196.2 0.0 1.4 2 0 0 2 2 2 1 Spc97 / Spc98 family HSP70 PF00012.15 CAM69519.1 - 2.4e-272 904.2 5.2 2.7e-272 904.0 3.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CAM69519.1 - 2.3e-14 52.7 0.1 3.2e-13 48.9 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 CAM69519.1 - 0.015 15.1 0.7 0.67 9.8 0.5 3.2 1 1 0 1 1 1 0 Cell division protein FtsA FGGY_C PF02782.11 CAM69519.1 - 0.022 14.3 0.0 0.053 13.1 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain HSP70 PF00012.15 CAM69520.2 - 2.4e-272 904.2 5.2 2.7e-272 904.0 3.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CAM69520.2 - 2.3e-14 52.7 0.1 3.2e-13 48.9 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 CAM69520.2 - 0.015 15.1 0.7 0.67 9.8 0.5 3.2 1 1 0 1 1 1 0 Cell division protein FtsA FGGY_C PF02782.11 CAM69520.2 - 0.022 14.3 0.0 0.053 13.1 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain TPR_MLP1_2 PF07926.7 CAM69521.1 - 0.17 11.6 8.1 0.075 12.7 0.9 3.1 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein FadA PF09403.5 CAM69521.1 - 2.6 8.0 9.1 5.8 6.9 4.5 2.6 2 1 0 2 2 2 0 Adhesion protein FadA Beta-lactamase PF00144.19 CAM69522.1 - 1.1e-10 41.1 0.2 3.7e-10 39.3 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase LIM PF00412.17 CAM69522.1 - 0.15 12.1 0.1 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 LIM domain HSP70 PF00012.15 CAM69524.1 - 6.4e-195 648.5 4.6 7.8e-195 648.2 3.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CAM69524.1 - 8.9e-18 63.9 1.3 1.7e-14 53.1 0.1 2.5 2 0 0 2 2 2 2 MreB/Mbl protein DDR PF08841.5 CAM69524.1 - 0.0011 17.9 1.2 0.0042 15.9 0.3 2.3 1 1 1 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.1 CAM69524.1 - 0.031 14.1 5.8 0.15 11.9 0.0 4.2 3 2 0 3 3 3 0 Cell division protein FtsA Hydantoinase_A PF01968.13 CAM69524.1 - 0.15 11.1 11.6 0.62 9.1 0.2 3.6 2 2 0 3 3 3 0 Hydantoinase/oxoprolinase DUF1454 PF07305.7 CAM69526.1 - 0.079 12.0 0.6 0.23 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1454) F-box PF00646.28 CAM69527.1 - 0.093 12.4 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 F-box domain Ldh_1_N PF00056.18 CAM69528.1 - 1.1e-33 116.0 0.1 1.9e-33 115.2 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CAM69528.1 - 5.9e-32 110.7 0.0 1e-31 109.9 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Lipase_GDSL_2 PF13472.1 CAM69528.1 - 0.11 12.6 0.8 1.5 8.9 0.5 2.1 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Dynein_heavy PF03028.10 CAM69530.2 - 1.2e-185 618.6 0.0 3.5e-185 617.0 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 CAM69530.2 - 6.6e-97 324.5 0.4 6.6e-97 324.5 0.3 3.8 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CAM69530.2 - 2.2e-85 285.8 0.5 6.4e-85 284.3 0.0 2.1 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 CAM69530.2 - 4.4e-73 245.5 0.0 1e-72 244.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.2 CAM69530.2 - 1e-43 149.3 0.0 6.9e-43 146.6 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_9 PF12781.2 CAM69530.2 - 4e-43 146.8 0.1 3.2e-42 143.9 0.1 2.3 1 1 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 CAM69530.2 - 7.5e-43 146.5 10.8 1.6e-42 145.4 7.5 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 CAM69530.2 - 2.5e-24 85.5 0.0 2.1e-06 27.4 0.0 6.2 6 1 0 6 6 6 4 AAA domain (dynein-related subfamily) AAA PF00004.24 CAM69530.2 - 1.1e-08 35.3 0.2 0.05 13.7 0.0 5.0 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CAM69530.2 - 1.2e-06 28.7 0.6 1.9 8.6 0.0 5.6 5 0 0 5 5 5 2 AAA domain AAA_14 PF13173.1 CAM69530.2 - 7.7e-05 22.6 0.0 0.69 9.8 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 CAM69530.2 - 0.00012 21.8 1.9 0.36 10.6 0.0 4.1 4 0 0 4 4 4 2 Part of AAA domain AAA_18 PF13238.1 CAM69530.2 - 0.00015 22.0 0.0 0.78 10.0 0.0 5.0 4 0 0 4 4 4 1 AAA domain AAA_17 PF13207.1 CAM69530.2 - 0.00023 21.9 0.0 0.34 11.7 0.0 5.0 4 0 0 4 4 4 1 AAA domain ResIII PF04851.10 CAM69530.2 - 0.0003 20.6 0.6 0.37 10.5 0.0 4.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_16 PF13191.1 CAM69530.2 - 0.00094 19.2 16.6 0.56 10.1 0.0 7.2 7 1 1 8 8 7 2 AAA ATPase domain RNA_helicase PF00910.17 CAM69530.2 - 0.0037 17.4 0.0 0.31 11.2 0.0 3.7 3 0 0 3 3 3 1 RNA helicase Dor1 PF04124.7 CAM69532.1 - 1.3e-23 83.0 7.1 1.8e-23 82.5 4.9 1.1 1 0 0 1 1 1 1 Dor1-like family Sec5 PF15469.1 CAM69532.1 - 0.0091 15.7 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec5 ArsC PF03960.10 CAM69532.1 - 0.15 12.1 0.2 0.47 10.5 0.1 1.9 1 0 0 1 1 1 0 ArsC family ELFV_dehydrog PF00208.16 CAM69533.1 - 6.8e-89 297.6 4.3 9.1e-89 297.2 3.0 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 CAM69533.1 - 2.7e-49 166.0 0.0 1.7e-47 160.2 0.0 3.0 3 0 0 3 3 3 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 CAM69533.1 - 0.00018 21.6 0.1 0.00034 20.8 0.1 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 CAM69533.1 - 0.0013 17.9 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 CAM69533.1 - 0.0015 18.1 0.0 0.0036 16.8 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Crinivirus_P26 PF07416.6 CAM69533.1 - 0.14 11.6 0.1 0.26 10.7 0.1 1.4 1 0 0 1 1 1 0 Crinivirus P26 protein Na_sulph_symp PF00939.14 CAM69535.1 - 2.3e-17 63.0 45.8 3.9e-16 58.9 31.7 2.9 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region SPX PF03105.14 CAM69535.1 - 1.4e-13 51.2 8.3 2.6e-10 40.5 5.8 2.7 1 1 0 1 1 1 1 SPX domain zf-CCCH PF00642.19 CAM69537.1 - 0.016 14.8 6.0 0.5 10.1 0.7 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Lactamase_B PF00753.22 CAM69538.1 - 0.045 13.3 0.5 1.1 8.9 0.0 2.6 2 2 0 2 2 2 0 Metallo-beta-lactamase superfamily PQQ_3 PF13570.1 CAM69538.1 - 0.93 9.8 16.5 30 5.0 0.2 5.5 6 0 0 6 6 6 0 PQQ-like domain DUF1192 PF06698.6 CAM69542.1 - 0.034 13.9 0.0 0.034 13.9 0.0 2.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) DASH_Hsk3 PF08227.6 CAM69542.1 - 0.28 11.4 1.5 0.31 11.2 0.1 1.7 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like Lzipper-MIP1 PF14389.1 CAM69542.1 - 0.52 10.4 7.3 0.62 10.2 0.0 3.0 3 1 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 FliL PF03748.9 CAM69542.1 - 3 7.8 6.3 4.7 7.2 1.5 2.5 2 1 0 2 2 2 0 Flagellar basal body-associated protein FliL Pkinase PF00069.20 CAM69543.1 - 1.7e-48 165.0 0.0 2.1e-48 164.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM69543.1 - 1.1e-26 93.5 0.0 1.3e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM69543.1 - 1e-05 24.6 0.0 1.5e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Cas_Cmr3 PF09700.5 CAM69543.1 - 0.0077 15.6 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Cmr3) Acetyltransf_1 PF00583.19 CAM69544.1 - 2.9e-13 49.6 0.0 4.7e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CAM69544.1 - 3.8e-10 39.7 0.0 5.6e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CAM69544.1 - 1.5e-06 28.3 0.0 1.7e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CAM69544.1 - 4.3e-05 23.3 0.0 6.1e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CAM69544.1 - 0.0034 17.2 0.1 0.0049 16.7 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 CAM69544.1 - 0.0054 16.6 0.0 0.0076 16.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CAM69544.1 - 0.0076 16.4 0.0 0.0091 16.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CAM69544.1 - 0.011 15.4 0.0 0.026 14.2 0.0 1.6 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_8 PF13523.1 CAM69544.1 - 0.11 12.4 0.0 0.28 11.0 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain ECH PF00378.15 CAM69546.1 - 3.2e-40 137.7 0.0 4.3e-40 137.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family FAD-oxidase_C PF02913.14 CAM69546.1 - 0.091 12.0 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain SPT16 PF08644.6 CAM69547.1 - 9.8e-36 122.8 1.8 2.2e-35 121.7 0.0 2.2 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) Rtt106 PF08512.7 CAM69547.1 - 2.8e-16 59.2 0.1 5e-15 55.2 0.0 2.6 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Peptidase_M24 PF00557.19 CAM69547.1 - 3.7e-14 52.7 0.0 1e-13 51.3 0.0 1.8 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF2153 PF09921.4 CAM69547.1 - 0.079 12.5 0.2 0.95 9.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2153) SDA1 PF05285.7 CAM69547.1 - 5.7 6.1 21.7 12 5.0 15.0 1.4 1 0 0 1 1 1 0 SDA1 Ribosomal_L3 PF00297.17 CAM69548.1 - 5.9e-13 48.8 0.1 1.2e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L3 PAP_PilO PF06864.7 CAM69550.1 - 0.11 10.8 0.0 0.19 10.0 0.0 1.3 1 0 0 1 1 1 0 Pilin accessory protein (PilO) tRNA-synt_1b PF00579.20 CAM69551.1 - 3.3e-20 72.3 0.0 1.6e-19 70.1 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) SNARE PF05739.14 CAM69552.1 - 6.7e-13 48.1 6.1 6.7e-13 48.1 4.2 2.4 2 1 0 2 2 2 1 SNARE domain DUF4175 PF13779.1 CAM69552.1 - 0.0044 14.7 6.0 0.0053 14.5 4.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) DUF4238 PF14022.1 CAM69552.1 - 0.0085 15.4 0.7 0.0085 15.4 0.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4238) Syntaxin_2 PF14523.1 CAM69552.1 - 0.0096 15.9 2.1 0.0096 15.9 1.4 2.3 2 0 0 2 2 2 1 Syntaxin-like protein RmuC PF02646.11 CAM69552.1 - 0.014 14.2 1.8 0.014 14.2 1.3 2.3 2 1 0 2 2 2 0 RmuC family MCPsignal PF00015.16 CAM69552.1 - 0.018 14.6 4.4 0.41 10.1 1.1 2.3 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.7 CAM69552.1 - 0.029 14.1 4.0 0.75 9.6 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) AHSP PF09236.5 CAM69552.1 - 0.049 13.8 0.2 0.6 10.3 0.0 2.2 2 0 0 2 2 2 0 Alpha-haemoglobin stabilising protein DUF3708 PF12501.3 CAM69552.1 - 0.058 13.2 0.5 0.24 11.2 0.1 2.0 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter Synaptobrevin PF00957.16 CAM69552.1 - 0.16 11.5 5.3 0.1 12.2 1.3 2.2 2 0 0 2 2 2 0 Synaptobrevin Halogen_Hydrol PF10112.4 CAM69552.1 - 0.66 9.3 4.1 4.4 6.6 0.2 2.4 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein TMPIT PF07851.8 CAM69552.1 - 0.89 8.5 4.0 0.88 8.5 0.3 2.1 2 0 0 2 2 2 0 TMPIT-like protein Syntaxin-6_N PF09177.6 CAM69552.1 - 0.97 9.8 10.2 2.6 8.5 1.1 2.7 2 1 0 2 2 2 0 Syntaxin 6, N-terminal V_ATPase_I PF01496.14 CAM69552.1 - 3 5.5 13.8 0.46 8.2 5.9 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Ras PF00071.17 CAM69554.1 - 1e-35 122.4 0.2 1.2e-35 122.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAM69554.1 - 3.3e-14 53.4 0.1 4.8e-14 52.8 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAM69554.1 - 2.4e-11 43.1 0.0 3.1e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CAM69554.1 - 1.3e-06 27.7 0.1 1.7e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CAM69554.1 - 2.1e-05 24.0 0.1 0.00012 21.5 0.1 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 CAM69554.1 - 0.0036 16.7 0.0 0.71 9.3 0.0 2.1 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 CAM69554.1 - 0.0047 16.8 0.0 0.0074 16.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase TDH PF03347.8 CAM69554.1 - 0.02 14.4 0.2 0.033 13.7 0.1 1.4 2 0 0 2 2 2 0 Vibrio thermostable direct hemolysin WD40 PF00400.27 CAM69555.1 - 2.3e-09 36.7 4.9 0.098 12.5 0.1 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat tify PF06200.9 CAM69555.1 - 0.0016 17.6 0.1 2.4 7.4 0.0 2.7 2 0 0 2 2 2 2 tify domain DOCK-C2 PF14429.1 CAM69556.1 - 1.1e-32 113.1 0.0 2.4e-32 112.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins PC_rep PF01851.17 CAM69557.1 - 1.1e-23 82.0 14.5 3.1e-05 23.9 0.0 9.1 9 0 0 9 9 9 4 Proteasome/cyclosome repeat HEAT_EZ PF13513.1 CAM69557.1 - 0.039 14.4 5.0 3.2 8.3 0.1 5.3 5 1 1 6 6 6 0 HEAT-like repeat TipAS PF07739.8 CAM69557.1 - 0.057 13.7 0.1 0.18 12.1 0.0 1.9 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain IQ PF00612.22 CAM69558.1 - 3.9 7.3 17.7 0.053 13.1 2.4 3.4 3 0 0 3 3 3 0 IQ calmodulin-binding motif RNA_pol_A_bac PF01000.21 CAM69559.1 - 1.4e-20 73.4 0.0 2.6e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CAM69559.1 - 1.8e-14 52.5 0.0 2.4e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_9 PF13187.1 CAM69559.1 - 0.013 15.7 2.0 0.013 15.7 1.4 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_7 PF12838.2 CAM69559.1 - 0.047 14.0 1.2 0.047 14.0 0.8 2.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain TPR_19 PF14559.1 CAM69560.1 - 1.1e-17 64.0 16.8 0.00036 20.8 0.5 6.5 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 CAM69560.1 - 1.8e-17 62.7 21.5 2.2e-06 27.2 0.4 6.5 4 2 2 6 6 6 5 TPR repeat TPR_12 PF13424.1 CAM69560.1 - 1.4e-13 50.6 16.3 8.3e-05 22.4 0.3 7.2 5 3 3 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.12 CAM69560.1 - 9.7e-12 43.8 23.5 5.6e-05 22.7 0.0 9.2 9 0 0 9 9 9 3 Tetratricopeptide repeat Apc3 PF12895.2 CAM69560.1 - 1.9e-11 43.9 22.2 1.1e-07 31.9 2.9 5.2 4 1 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 CAM69560.1 - 3.9e-10 40.1 20.8 4.6e-07 30.3 0.1 6.5 6 2 2 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 CAM69560.1 - 3.5e-09 36.4 7.7 0.048 14.3 0.0 7.6 6 2 2 8 8 7 2 Tetratricopeptide repeat TPR_1 PF00515.23 CAM69560.1 - 2.5e-08 33.1 20.3 0.016 14.8 0.1 7.9 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 CAM69560.1 - 5.1e-06 25.8 3.3 3.7 7.5 0.0 7.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 CAM69560.1 - 6.3e-05 23.1 27.0 0.012 15.9 0.0 8.8 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_10 PF13374.1 CAM69560.1 - 0.00051 19.8 12.8 0.66 9.9 0.0 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 CAM69560.1 - 0.00074 19.3 3.8 0.015 15.0 0.4 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Type_III_YscG PF09477.5 CAM69560.1 - 0.0016 18.4 1.0 1.9 8.5 0.0 2.9 1 1 1 2 2 2 2 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_3 PF07720.7 CAM69560.1 - 0.0054 16.5 0.1 0.0054 16.5 0.1 4.3 6 0 0 6 6 3 1 Tetratricopeptide repeat PPR PF01535.15 CAM69560.1 - 0.0097 15.8 6.7 16 5.7 0.1 4.9 5 0 0 5 5 4 0 PPR repeat Foie-gras_1 PF11817.3 CAM69560.1 - 0.016 14.6 10.0 0.052 13.0 0.3 3.8 3 1 1 4 4 4 0 Foie gras liver health family 1 HrpB1_HrpK PF09613.5 CAM69560.1 - 0.034 13.6 1.3 0.17 11.3 0.0 2.8 3 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_8 PF13181.1 CAM69560.1 - 0.071 12.9 16.2 0.51 10.2 0.1 6.3 7 0 0 7 7 5 0 Tetratricopeptide repeat PPR_3 PF13812.1 CAM69560.1 - 0.2 12.0 4.1 54 4.4 0.0 5.1 5 0 0 5 5 3 0 Pentatricopeptide repeat domain TPR_17 PF13431.1 CAM69560.1 - 0.64 10.3 8.3 18 5.8 0.3 5.3 6 0 0 6 6 4 0 Tetratricopeptide repeat NARP1 PF12569.3 CAM69560.1 - 0.78 8.4 16.1 0.13 10.9 0.7 3.6 3 1 1 4 4 4 0 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.1 CAM69560.1 - 1.1 9.1 17.1 6.7 6.6 0.1 5.3 3 1 2 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat IPP-2 PF04979.9 CAM69578.1 - 2e-09 37.7 5.7 4.3e-09 36.7 3.9 1.5 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) FlgM PF04316.8 CAM69578.1 - 0.14 12.1 0.6 0.25 11.3 0.1 1.7 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM zf-RanBP PF00641.13 CAM69579.1 - 0.01 14.9 7.7 0.01 14.9 5.4 1.7 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Pox_P4B PF03292.9 CAM69580.1 - 0.12 10.3 0.8 0.18 9.7 0.6 1.1 1 0 0 1 1 1 0 Poxvirus P4B major core protein SNF2_N PF00176.18 CAM69581.1 - 2e-31 108.9 0.0 4.1e-31 107.8 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CAM69581.1 - 1.3e-06 28.1 0.0 2.6e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAM69581.1 - 6.3e-06 26.1 0.0 0.02 14.7 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CAM69581.1 - 0.1 12.7 0.1 0.37 10.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 CAM69581.1 - 0.11 11.9 0.6 0.53 9.7 0.0 2.3 2 1 1 3 3 3 0 DEAD/DEAH box helicase DUF2075 PF09848.4 CAM69581.1 - 0.42 9.5 0.0 0.78 8.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Remorin_C PF03763.8 CAM69582.1 - 1.3 8.5 9.9 0.16 11.4 3.4 2.0 2 1 0 2 2 2 0 Remorin, C-terminal region DUF217 PF02697.9 CAM69582.1 - 1.3 9.3 5.5 2.3 8.5 0.0 3.3 2 1 1 3 3 3 0 Uncharacterized ACR, COG1753 Sec23_trunk PF04811.10 CAM69583.1 - 6.4e-42 143.5 0.0 1.1e-41 142.8 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 CAM69583.1 - 3.8e-21 75.4 0.0 9.9e-21 74.0 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 CAM69583.1 - 1.4e-16 59.7 1.9 3e-16 58.7 1.3 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.10 CAM69583.1 - 2.5e-08 33.2 0.0 5.2e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain RIO1 PF01163.17 CAM69585.1 - 1e-65 220.6 0.3 3.6e-65 218.8 0.0 1.9 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 CAM69585.1 - 0.015 15.0 0.1 0.13 11.9 0.1 2.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family Glypican PF01153.14 CAM69585.1 - 0.36 9.3 3.7 10 4.6 1.6 2.1 2 0 0 2 2 2 0 Glypican CDC45 PF02724.9 CAM69585.1 - 7 4.5 8.5 9.6 4.0 5.9 1.2 1 0 0 1 1 1 0 CDC45-like protein DIOX_N PF14226.1 CAM69586.1 - 6.5e-34 116.9 0.0 9.8e-34 116.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CAM69586.1 - 4.5e-24 84.6 0.0 7.8e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TTL PF03133.10 CAM69587.1 - 2.8e-41 141.3 0.0 1.7e-18 66.5 0.0 3.1 3 0 0 3 3 3 3 Tubulin-tyrosine ligase family FAD-oxidase_C PF02913.14 CAM69589.1 - 2.3e-44 151.6 0.2 4e-44 150.8 0.1 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CAM69589.1 - 1.1e-37 128.5 0.5 1.1e-37 128.5 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain DUF77 PF01910.12 CAM69589.1 - 0.097 12.3 0.1 0.67 9.6 0.0 2.4 2 1 1 3 3 3 0 Domain of unknown function DUF77 zf-C2HC_2 PF13913.1 CAM69590.1 - 3.1e-19 68.1 9.0 2.6e-11 42.8 1.2 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2 PF00096.21 CAM69590.1 - 0.00027 21.0 3.8 0.053 13.8 0.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type TerY-C PF15616.1 CAM69590.1 - 0.00058 19.7 0.3 0.047 13.6 0.0 2.7 3 0 0 3 3 3 1 TerY-C metal binding domain zf-FPG_IleRS PF06827.9 CAM69590.1 - 0.00093 18.7 7.2 0.069 12.8 1.0 2.5 2 0 0 2 2 2 2 Zinc finger found in FPG and IleRS Sgf11 PF08209.6 CAM69590.1 - 0.0028 16.9 8.6 0.015 14.5 0.6 2.5 2 1 0 2 2 2 2 Sgf11 (transcriptional regulation protein) zf-RING_3 PF14369.1 CAM69590.1 - 0.013 15.4 3.0 3.6 7.6 0.3 2.7 2 0 0 2 2 2 0 zinc-finger zinc_ribbon_2 PF13240.1 CAM69590.1 - 0.017 14.6 3.5 2.8 7.5 0.0 2.8 2 1 0 2 2 2 0 zinc-ribbon domain DUF164 PF02591.10 CAM69590.1 - 0.023 14.5 0.7 5.6 6.8 0.1 2.7 2 0 0 2 2 2 0 Putative zinc ribbon domain zf-ribbon_3 PF13248.1 CAM69590.1 - 0.025 13.7 5.3 2.2 7.6 0.1 3.1 2 1 0 2 2 2 0 zinc-ribbon domain Lar_restr_allev PF14354.1 CAM69590.1 - 0.032 14.5 2.9 1.4 9.2 1.1 2.9 2 1 1 3 3 3 0 Restriction alleviation protein Lar HypA PF01155.14 CAM69590.1 - 0.075 12.7 1.0 11 5.7 0.0 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 CAM69590.1 - 0.078 12.9 2.5 7.9 6.5 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-Di19 PF05605.7 CAM69590.1 - 0.081 13.0 9.2 0.16 12.1 0.7 2.7 3 0 0 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding zf-CHCC PF10276.4 CAM69590.1 - 0.11 12.3 0.6 4.5 7.1 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger domain DZR PF12773.2 CAM69590.1 - 0.14 11.9 2.0 13 5.7 0.2 2.5 2 0 0 2 2 2 0 Double zinc ribbon zf-C2H2_4 PF13894.1 CAM69590.1 - 0.25 11.7 6.4 6 7.4 1.9 3.1 2 1 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CAM69590.1 - 0.29 11.5 5.3 3.3 8.1 0.1 2.7 3 0 0 3 3 2 0 Zinc-finger double domain DUF329 PF03884.9 CAM69590.1 - 0.52 9.8 3.3 2.7 7.6 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF329) Nairovirus_M PF07948.6 CAM69590.1 - 0.65 8.0 3.9 0.72 7.8 0.2 2.0 2 0 0 2 2 2 0 Nairovirus M polyprotein-like Zn_Tnp_IS1595 PF12760.2 CAM69590.1 - 1.1 9.1 3.6 10 6.0 0.6 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain PAAR_motif PF05488.8 CAM69590.1 - 3.3 7.7 7.9 0.92 9.5 0.1 3.6 3 2 2 5 5 5 0 PAAR motif Prim_Zn_Ribbon PF08273.7 CAM69590.1 - 5.3 7.2 6.2 20 5.3 0.3 2.7 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase FHA PF00498.21 CAM69591.1 - 6.9e-08 32.5 0.0 0.0017 18.4 0.0 2.3 2 0 0 2 2 2 2 FHA domain TPR_11 PF13414.1 CAM69592.1 - 8e-14 51.0 4.6 2e-10 40.1 1.7 2.5 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 CAM69592.1 - 4.3e-08 32.4 3.1 0.19 11.7 0.5 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 CAM69592.1 - 3.5e-06 26.7 0.3 0.043 14.0 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 CAM69592.1 - 9.2e-06 25.0 0.6 0.0043 16.6 0.3 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 CAM69592.1 - 2.1e-05 24.2 0.2 2.1e-05 24.2 0.1 2.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 CAM69592.1 - 3.3e-05 24.4 1.1 3.3e-05 24.4 0.7 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.1 CAM69592.1 - 0.00087 18.4 4.1 0.0034 16.5 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CAM69592.1 - 0.036 13.8 0.2 61 3.7 0.0 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 CAM69592.1 - 0.21 12.3 0.3 0.21 12.3 0.2 4.4 3 2 2 5 5 4 0 Tetratricopeptide repeat DUF2999 PF11212.3 CAM69592.1 - 0.32 11.0 4.7 26 4.9 3.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2999) NARP1 PF12569.3 CAM69592.1 - 5.2 5.7 12.2 1.1 7.9 5.2 1.9 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 ArfGap PF01412.13 CAM69593.1 - 3.6e-39 133.1 0.1 7.2e-39 132.1 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SelP_N PF04592.9 CAM69593.1 - 4.3 6.6 9.2 7 5.9 6.4 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RRN7 PF11781.3 CAM69593.1 - 7.3 6.1 9.3 0.26 10.8 2.2 1.7 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Zip PF02535.17 CAM69593.1 - 8.1 5.3 5.6 12 4.7 3.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter UBA_4 PF14555.1 CAM69594.1 - 7.6e-07 28.5 0.1 1.5e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.1 CAM69594.1 - 0.0012 18.8 0.1 0.0029 17.5 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like zf-met PF12874.2 CAM69596.1 - 0.0099 16.0 0.4 0.019 15.1 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CAM69596.1 - 0.039 13.8 0.4 0.075 12.9 0.3 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger AKAP95 PF04988.7 CAM69596.1 - 0.068 12.9 0.1 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) Pkinase PF00069.20 CAM69597.2 - 1.8e-41 142.0 0.0 9.4e-21 74.1 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CAM69597.2 - 2.6e-23 82.4 0.1 1.1e-14 54.0 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 CAM69597.2 - 0.00049 19.1 0.0 0.47 9.3 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 CAM69597.2 - 0.003 17.3 0.5 0.023 14.4 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CAM69597.2 - 0.037 12.8 0.1 0.055 12.2 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 CAM69597.2 - 0.39 10.0 0.0 0.92 8.8 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 CAM69597.2 - 0.43 9.6 0.0 0.83 8.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3451 PF11933.3 CAM69598.1 - 2.5e-36 125.5 1.2 6.2e-36 124.2 0.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3451) DUF3250 PF11618.3 CAM69598.1 - 0.007 16.5 0.0 0.007 16.5 0.0 3.9 4 0 0 4 4 4 1 Protein of unknown function (DUF3250) Fez1 PF06818.10 CAM69598.1 - 6.6 6.6 59.7 1.4 8.9 14.7 4.2 4 0 0 4 4 4 0 Fez1 AAA_23 PF13476.1 CAM69599.1 - 2.1 8.6 5.2 6.9 6.9 0.7 2.3 2 0 0 2 2 2 0 AAA domain Metal_resist PF13801.1 CAM69600.1 - 0.017 15.0 3.7 0.047 13.6 0.4 2.6 2 0 0 2 2 2 0 Heavy-metal resistance Gly-zipper_OmpA PF13436.1 CAM69600.1 - 0.031 13.9 0.4 0.031 13.9 0.3 2.9 3 0 0 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_Omp PF13488.1 CAM69600.1 - 0.2 11.3 13.7 0.037 13.6 5.7 2.4 2 0 0 2 2 2 0 Glycine zipper Rick_17kDa_Anti PF05433.10 CAM69600.1 - 2 8.1 18.5 0.33 10.6 8.3 2.5 2 0 0 2 2 2 0 Glycine zipper 2TM domain RRM_1 PF00076.17 CAM69601.1 - 1.3e-14 53.5 0.1 1e-06 28.2 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM69601.1 - 1.3e-08 34.6 0.2 0.00092 19.1 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM69601.1 - 4.5e-07 29.6 0.3 0.00071 19.3 0.1 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CAM69601.1 - 0.019 14.7 0.3 0.86 9.4 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RNA_pol_Rpb4 PF03874.11 CAM69602.1 - 1.9e-05 24.6 0.0 5.5e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb4 Prolamin_like PF05617.6 CAM69602.1 - 0.023 14.8 0.1 0.044 13.9 0.0 1.5 1 0 0 1 1 1 0 Prolamin-like zf-CCCH PF00642.19 CAM69604.1 - 0.033 13.8 0.4 0.048 13.3 0.3 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PPR_3 PF13812.1 CAM69605.1 - 6.9e-05 22.8 0.6 0.32 11.3 0.1 4.9 5 0 0 5 5 5 1 Pentatricopeptide repeat domain DUF3366 PF11846.3 CAM69605.1 - 0.011 15.6 1.8 0.37 10.6 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3366) PPR_2 PF13041.1 CAM69605.1 - 0.015 15.2 0.0 0.1 12.6 0.0 2.4 2 0 0 2 2 2 0 PPR repeat family PPR PF01535.15 CAM69605.1 - 0.06 13.3 0.0 28 5.0 0.0 3.6 3 0 0 3 3 3 0 PPR repeat PPR_1 PF12854.2 CAM69605.1 - 0.1 12.1 0.0 0.37 10.3 0.0 1.9 2 0 0 2 2 2 0 PPR repeat Metallophos PF00149.23 CAM69606.1 - 0.0019 17.6 0.0 0.05 12.9 0.0 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CAM69606.1 - 0.067 13.0 0.0 0.12 12.1 0.0 1.5 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Rad51 PF08423.6 CAM69607.1 - 3.5e-13 49.0 0.4 2.7e-06 26.4 0.0 3.2 3 0 0 3 3 3 3 Rad51 RecA PF00154.16 CAM69607.1 - 2.6e-09 36.6 2.3 1.2e-07 31.1 0.1 2.1 2 0 0 2 2 2 2 recA bacterial DNA recombination protein KaiC PF06745.8 CAM69607.1 - 1.7e-07 30.5 0.0 3.5e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 CAM69607.1 - 0.75 9.1 10.6 10 5.4 5.4 2.9 2 1 0 2 2 2 0 AAA domain CaATP_NAI PF12515.3 CAM69610.2 - 2.9e-17 61.9 0.1 8e-17 60.4 0.1 1.8 1 0 0 1 1 1 1 Ca2+-ATPase N terminal autoinhibitory domain Cofilin_ADF PF00241.15 CAM69611.1 - 6.5e-30 103.6 0.1 7.3e-30 103.4 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein RNase_T PF00929.19 CAM69614.1 - 6.2e-25 88.3 0.0 7.1e-18 65.4 0.0 2.3 1 1 1 2 2 2 2 Exonuclease LIN37 PF15306.1 CAM69614.1 - 0.13 12.2 0.8 0.31 11.0 0.1 2.0 2 0 0 2 2 2 0 LIN37 Phage_int_SAM_2 PF12834.2 CAM69614.1 - 0.49 10.8 2.3 0.4 11.1 0.3 1.8 2 0 0 2 2 2 0 Phage integrase, N-terminal Menin PF05053.8 CAM69614.1 - 0.81 7.7 3.9 1.5 6.9 2.7 1.3 1 0 0 1 1 1 0 Menin RNase_T PF00929.19 CAM69615.1 - 6.9e-25 88.2 0.0 9.7e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Exonuclease RNase_T PF00929.19 CAM69616.1 - 9.6e-25 87.7 0.0 1.7e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 Exonuclease Ank_2 PF12796.2 CAM69617.1 - 2.8e-10 40.3 0.1 9.3e-10 38.7 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CAM69617.1 - 4.6e-09 35.6 1.7 0.074 12.9 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 CAM69617.1 - 5.9e-09 36.2 0.7 0.0017 18.7 0.1 3.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CAM69617.1 - 5.6e-06 26.0 0.5 0.31 11.3 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CAM69617.1 - 1.1e-05 25.5 2.7 0.047 13.9 0.3 3.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) AF1Q PF15017.1 CAM69618.1 - 0.004 17.0 0.1 0.042 13.7 0.0 2.2 2 0 0 2 2 2 1 Drug resistance and apoptosis regulator ResIII PF04851.10 CAM69619.2 - 2.9e-13 50.0 0.0 4.5e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CAM69619.2 - 5.2e-09 35.8 0.0 1.6e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_3 PF13625.1 CAM69619.2 - 4.9e-06 26.3 0.1 1.4e-05 24.8 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAM69619.2 - 0.00032 20.2 0.1 0.00051 19.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-NF-X1 PF01422.12 CAM69620.1 - 8.8e-07 28.7 60.6 2.4e-05 24.1 8.8 15.0 16 2 1 17 17 17 6 NF-X1 type zinc finger zf-CCHC_2 PF13696.1 CAM69621.1 - 5.9e-06 25.6 0.7 2e-05 23.9 0.5 2.0 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_jaz PF12171.3 CAM69621.1 - 2.3e-05 24.3 1.1 6.4e-05 22.9 0.6 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 CAM69621.1 - 0.0042 17.3 2.4 0.079 13.3 0.1 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type NUFIP1 PF10453.4 CAM69621.1 - 0.0095 15.4 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) eIF3g PF12353.3 CAM69621.1 - 0.012 15.5 0.1 0.012 15.5 0.1 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G zf-LITAF-like PF10601.4 CAM69621.1 - 0.021 14.6 0.9 0.026 14.3 0.0 1.5 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain zf-C2H2_6 PF13912.1 CAM69621.1 - 0.035 14.0 0.7 0.035 14.0 0.5 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 CAM69621.1 - 0.062 13.5 0.3 0.15 12.3 0.2 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 CAM69621.1 - 0.14 12.5 0.3 0.14 12.5 0.2 3.4 2 1 1 3 3 3 0 C2H2-type zinc finger zf-CCHC_5 PF14787.1 CAM69621.1 - 0.19 11.2 6.7 0.027 13.9 1.2 2.1 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger ABC2_membrane_3 PF12698.2 CAM69622.1 - 9.2e-56 189.3 61.6 1.1e-36 126.6 17.6 3.3 3 0 0 3 3 3 2 ABC-2 family transporter protein ABC_tran PF00005.22 CAM69622.1 - 8.6e-55 184.7 0.0 2.7e-27 95.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CAM69622.1 - 1.8e-11 44.5 1.5 0.003 17.5 0.0 4.5 3 1 0 4 4 4 3 AAA domain SMC_N PF02463.14 CAM69622.1 - 2.5e-09 36.6 0.0 0.00017 20.8 0.1 3.2 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CAM69622.1 - 4.5e-06 26.1 1.4 0.0021 17.5 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 CAM69622.1 - 0.00086 19.3 0.2 0.055 13.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.1 CAM69622.1 - 0.0014 19.0 0.8 0.29 11.4 0.1 2.2 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 CAM69622.1 - 0.0017 17.5 0.1 0.54 9.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 CAM69622.1 - 0.0025 17.2 0.2 1.8 7.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 CAM69622.1 - 0.01 15.4 1.6 0.44 10.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 CAM69622.1 - 0.01 15.6 0.0 2.6 8.0 0.0 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 CAM69622.1 - 0.031 14.4 0.4 4.6 7.4 0.0 2.9 3 0 0 3 3 2 0 RNA helicase AAA PF00004.24 CAM69622.1 - 0.17 12.0 0.6 3.2 7.9 0.1 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.17 CAM69622.1 - 0.21 11.0 4.6 0.33 10.3 0.4 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_33 PF13671.1 CAM69622.1 - 0.23 11.3 0.5 28 4.5 0.0 2.9 2 1 0 2 2 2 0 AAA domain ABC2_membrane_2 PF12679.2 CAM69622.1 - 0.5 9.1 31.5 0.15 10.8 6.4 2.7 2 1 0 2 2 2 0 ABC-2 family transporter protein UPF0079 PF02367.12 CAM69622.1 - 0.81 9.3 2.2 26 4.4 0.2 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_13 PF13166.1 CAM69622.1 - 3.4 6.0 1.1 17 3.6 0.1 2.0 2 0 0 2 2 2 0 AAA domain SNARE PF05739.14 CAM69624.1 - 4.7e-08 32.6 1.7 6.9e-08 32.0 1.2 1.2 1 0 0 1 1 1 1 SNARE domain Treslin_N PF15292.1 CAM69624.1 - 0.018 12.9 0.0 0.02 12.8 0.0 1.0 1 0 0 1 1 1 0 Treslin N-terminus DUF919 PF06034.6 CAM69624.1 - 0.057 13.0 0.4 0.096 12.3 0.3 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) YukC PF10140.4 CAM69624.1 - 0.1 11.1 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC DcpS_C PF11969.3 CAM69625.1 - 3.6e-24 85.2 0.8 1e-23 83.7 0.3 1.9 3 0 0 3 3 3 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 CAM69625.1 - 2.5e-13 50.3 0.5 9.3e-13 48.5 0.1 2.0 3 0 0 3 3 3 1 HIT domain zf-C2H2_2 PF12756.2 CAM69625.1 - 0.047 13.7 0.2 0.093 12.8 0.1 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) PHO4 PF01384.15 CAM69626.1 - 1.7e-96 322.6 14.5 2.5e-96 322.1 10.0 1.2 1 0 0 1 1 1 1 Phosphate transporter family Radial_spoke PF04712.7 CAM69627.1 - 6.8e-145 483.5 0.0 9.2e-145 483.1 0.0 1.0 1 0 0 1 1 1 1 Radial spokehead-like protein RRM_1 PF00076.17 CAM69629.2 - 4.3e-22 77.5 0.0 2e-13 49.7 0.0 3.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM69629.2 - 8.1e-18 64.1 0.0 8.9e-09 35.2 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM69629.2 - 5.5e-15 54.9 0.0 0.00038 20.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RHD3 PF05879.7 CAM69630.1 - 0.011 13.6 0.0 0.014 13.4 0.0 1.0 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) CLAMP PF14769.1 CAM69631.1 - 0.017 15.2 0.0 9.8 6.3 0.0 2.5 2 0 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 FG-GAP PF01839.18 CAM69632.1 - 0.00028 20.5 1.3 0.006 16.2 0.6 2.6 2 0 0 2 2 2 1 FG-GAP repeat BBS2_Mid PF14783.1 CAM69632.1 - 0.00033 20.3 0.3 0.45 10.3 0.1 2.7 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region BBS2_C PF14782.1 CAM69632.1 - 0.0054 15.3 1.0 0.033 12.7 0.0 2.3 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, C-terminal VCBS PF13517.1 CAM69632.1 - 0.0079 16.5 0.1 0.028 14.7 0.1 1.9 1 0 0 1 1 1 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PQQ_2 PF13360.1 CAM69632.1 - 0.019 14.4 0.2 0.054 12.9 0.1 1.7 1 0 0 1 1 1 0 PQQ-like domain EF_TS PF00889.14 CAM69633.1 - 1.2e-17 64.0 0.0 3.1e-17 62.6 0.0 1.6 1 1 1 2 2 2 1 Elongation factor TS UBA PF00627.26 CAM69633.1 - 0.00057 19.6 0.1 0.0061 16.3 0.0 2.3 2 0 0 2 2 2 1 UBA/TS-N domain WD40 PF00400.27 CAM69635.1 - 2.6e-31 106.3 12.9 3.1e-06 26.8 0.0 6.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Mpp10 PF04006.7 CAM69636.1 - 1.8e-58 198.4 35.7 9.8e-58 195.9 24.7 2.3 1 1 0 1 1 1 1 Mpp10 protein Glypican PF01153.14 CAM69636.1 - 0.14 10.7 3.1 0.31 9.5 2.1 1.6 1 0 0 1 1 1 0 Glypican HSP90 PF00183.13 CAM69637.1 - 3e-147 491.2 11.2 3.8e-147 490.9 7.8 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 CAM69637.1 - 2.4e-10 40.1 0.0 6.3e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CAM69637.1 - 8.7e-05 22.2 0.0 0.00023 20.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GSH-S_ATP PF02955.11 CAM69637.1 - 0.0076 15.4 0.1 0.21 10.6 0.0 2.4 2 0 0 2 2 2 1 Prokaryotic glutathione synthetase, ATP-grasp domain Plasmid_RAQPRD PF09686.5 CAM69638.1 - 0.11 12.5 4.0 7.2 6.7 0.1 2.4 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Vma12 PF11712.3 CAM69638.1 - 0.11 12.1 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3752 PF12572.3 CAM69638.1 - 0.98 9.5 6.4 0.15 12.1 1.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) U-box PF04564.10 CAM69639.1 - 5e-12 45.5 0.0 3.6e-11 42.8 0.0 2.4 3 0 0 3 3 3 1 U-box domain zf-Nse PF11789.3 CAM69639.1 - 1.1e-05 24.8 0.0 2.9e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit VESA1_N PF12785.2 CAM69639.1 - 0.24 10.3 0.1 5 5.9 0.0 2.1 2 0 0 2 2 2 0 Variant erythrocyte surface antigen-1 Peptidase_U35_2 PF14550.1 CAM69640.1 - 0.24 11.0 0.1 0.57 9.8 0.1 1.6 1 0 0 1 1 1 0 Putative phage protease XkdF Peptidase_C1 PF00112.18 CAM69644.1 - 1.3e-59 201.7 4.1 1.6e-59 201.4 2.9 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 CAM69644.1 - 0.00026 19.6 2.1 0.0027 16.3 0.4 2.0 2 0 0 2 2 2 2 Peptidase C1-like family Propeptide_C1 PF08127.8 CAM69644.1 - 0.0007 19.1 0.0 0.0015 18.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase family C1 propeptide Nop14 PF04147.7 CAM69645.1 - 3 5.6 9.2 3.9 5.2 6.4 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1634 PF07843.6 CAM69646.1 - 0.086 12.4 5.2 2 8.0 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1634) HMG_box PF00505.14 CAM69647.1 - 1.8e-33 114.5 11.6 9.7e-21 73.8 0.9 3.0 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 CAM69647.1 - 7.4e-22 77.5 21.4 3.3e-13 49.8 0.6 3.2 3 1 0 3 3 3 2 HMG-box domain DEK_C PF08766.6 CAM69647.1 - 1.7e-06 27.6 0.1 3e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 DEK C terminal domain HMG_box_5 PF14887.1 CAM69647.1 - 6e-06 25.9 18.1 5.9e-05 22.7 0.9 3.1 3 0 0 3 3 3 2 HMG (high mobility group) box 5 DUF736 PF05284.7 CAM69647.1 - 0.0013 18.5 1.0 1.7 8.5 0.1 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF736) PDCD9 PF07147.7 CAM69647.1 - 0.0013 17.5 0.7 0.0016 17.2 0.5 1.2 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S30 (PDCD9) DUF1074 PF06382.6 CAM69647.1 - 0.0025 17.7 15.4 0.0073 16.3 1.9 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1074) YABBY PF04690.8 CAM69647.1 - 0.016 15.4 1.3 0.016 15.4 0.9 1.7 2 0 0 2 2 2 0 YABBY protein DUF2582 PF10771.4 CAM69647.1 - 1.4 8.8 3.8 9.9 6.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2582) RRM_5 PF13893.1 CAM69649.1 - 7.9e-10 38.4 0.1 1.1e-09 37.9 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM69649.1 - 1.3e-08 34.6 0.0 1.7e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAM69649.1 - 6.2e-07 28.9 0.0 9.8e-07 28.3 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Amidohydro_1 PF01979.15 CAM69650.1 - 4.6e-38 131.6 0.0 6.5e-38 131.2 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 CAM69650.1 - 5.9e-09 35.6 0.0 1.5e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 CAM69650.1 - 3.1e-08 33.9 0.1 1.7e-07 31.5 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 CAM69650.1 - 0.028 13.6 0.0 6.5 5.8 0.0 2.9 2 1 0 3 3 3 0 Amidohydrolase family Cyt-b5 PF00173.23 CAM69651.1 - 3e-09 36.5 0.0 4.3e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Arf PF00025.16 CAM69653.1 - 1.2e-64 216.7 0.0 1.3e-64 216.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CAM69653.1 - 2.9e-15 55.9 0.0 3.6e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CAM69653.1 - 1.1e-14 54.0 0.0 1.3e-14 53.8 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CAM69653.1 - 2.6e-12 46.1 0.4 2.1e-09 36.5 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CAM69653.1 - 2.1e-11 43.4 0.0 2.4e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CAM69653.1 - 4.7e-10 40.0 0.0 6.1e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CAM69653.1 - 2.3e-09 37.2 0.0 3.2e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CAM69653.1 - 1.9e-05 24.1 0.0 0.00017 21.0 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.14 CAM69653.1 - 0.0028 17.1 0.0 0.057 12.8 0.0 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 CAM69653.1 - 0.055 13.1 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase PduV-EutP PF10662.4 CAM69653.1 - 0.081 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ArgK PF03308.11 CAM69653.1 - 0.09 11.5 0.1 0.73 8.5 0.0 2.1 1 1 0 1 1 1 0 ArgK protein AAA_16 PF13191.1 CAM69653.1 - 0.091 12.7 0.1 0.19 11.6 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.24 CAM69653.1 - 0.14 12.4 0.0 0.28 11.3 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhdYeFM_antitox PF02604.14 CAM69653.1 - 0.15 11.6 0.6 0.28 10.7 0.4 1.4 1 0 0 1 1 1 0 Antitoxin Phd_YefM, type II toxin-antitoxin system PhyH PF05721.8 CAM69654.1 - 1.5e-06 28.3 0.0 4.9e-06 26.7 0.0 1.9 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) C1_1 PF00130.17 CAM69654.1 - 0.00017 21.2 4.6 0.00053 19.6 3.2 1.8 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 CAM69654.1 - 0.00054 19.6 3.6 0.00054 19.6 2.5 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 PHD PF00628.24 CAM69654.1 - 0.18 11.4 10.4 0.5 10.0 7.2 1.8 1 1 0 1 1 1 0 PHD-finger OrfB_Zn_ribbon PF07282.6 CAM69654.1 - 0.82 9.3 10.6 1.3 8.7 4.1 2.5 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-RING_2 PF13639.1 CAM69654.1 - 2.8 7.8 11.0 2.5 8.0 5.9 2.2 2 0 0 2 2 2 0 Ring finger domain DUF914 PF06027.7 CAM69655.1 - 1.1e-63 215.0 26.6 2.8e-48 164.4 4.2 2.0 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 CAM69655.1 - 9.9e-08 32.0 37.7 9.1e-05 22.4 8.6 2.3 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 CAM69655.1 - 2.5e-05 23.9 25.7 0.0093 15.6 4.2 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family IPPT PF01715.12 CAM69656.1 - 8e-13 47.9 0.0 1.1e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 IPP transferase zf-met PF12874.2 CAM69656.1 - 1.1e-05 25.3 0.4 2e-05 24.6 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CAM69656.1 - 0.0081 16.2 0.4 0.014 15.5 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF3449 PF11931.3 CAM69656.1 - 0.047 13.1 0.0 0.08 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) DUF829 PF05705.9 CAM69656.1 - 0.093 12.4 0.0 11 5.6 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF829) Peptidase_A22B PF04258.8 CAM69657.1 - 1.4e-56 192.1 17.0 3.5e-55 187.5 8.2 2.1 1 1 1 2 2 2 2 Signal peptide peptidase DUF1119 PF06550.6 CAM69657.1 - 0.0051 15.9 14.5 0.026 13.6 10.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1119) LETM1 PF07766.8 CAM69658.1 - 7.6e-39 133.3 4.8 3.5e-30 104.9 0.1 2.9 3 0 0 3 3 3 2 LETM1-like protein Dpoe2NT PF12213.3 CAM69658.1 - 0.036 13.9 0.4 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 DNA polymerases epsilon N terminal ABC2_membrane PF01061.19 CAM69659.1 - 0.00058 19.0 19.2 0.00097 18.3 13.3 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 CAM69659.1 - 0.048 13.9 0.0 0.075 13.3 0.0 1.2 1 0 0 1 1 1 0 ABC transporter FGE-sulfatase PF03781.11 CAM69661.1 - 3.1e-21 75.8 1.3 6.6e-21 74.8 0.9 1.6 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Methyltransf_25 PF13649.1 CAM69661.1 - 3.6e-18 65.7 0.0 9e-18 64.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain DinB_2 PF12867.2 CAM69661.1 - 2.7e-06 27.7 0.0 6.9e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 DinB superfamily Methyltransf_23 PF13489.1 CAM69661.1 - 0.00037 20.2 0.5 0.0015 18.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAM69661.1 - 0.00045 20.7 0.0 0.0014 19.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAM69661.1 - 0.023 14.3 0.0 0.36 10.3 0.0 2.5 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_11 PF08241.7 CAM69661.1 - 0.08 13.4 0.0 0.24 11.9 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain DUF2938 PF11158.3 CAM69662.1 - 0.041 13.2 0.1 0.075 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2938) Kinesin PF00225.18 CAM69664.1 - 8e-83 277.9 0.0 8e-83 277.9 0.0 3.1 3 0 0 3 3 3 1 Kinesin motor domain DUF2713 PF10897.3 CAM69664.1 - 2 7.5 5.4 1.7 7.8 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2713) MAGSP PF03082.9 CAM69666.2 - 0.12 11.6 0.2 7.3 5.8 0.1 2.3 2 0 0 2 2 2 0 Male accessory gland secretory protein Baculo_PEP_C PF04513.7 CAM69667.1 - 6.2e-06 26.0 3.4 0.13 12.1 0.0 3.3 3 1 1 4 4 3 3 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 CAM69667.1 - 0.00064 18.9 0.7 0.17 11.0 0.7 2.5 2 0 0 2 2 2 1 Reovirus sigma C capsid protein Spc7 PF08317.6 CAM69667.1 - 0.002 16.8 0.6 0.002 16.8 0.4 3.1 3 0 0 3 3 3 1 Spc7 kinetochore protein COG5 PF10392.4 CAM69667.1 - 0.013 15.4 0.3 0.013 15.4 0.2 3.2 3 1 0 3 3 3 0 Golgi transport complex subunit 5 TBPIP PF07106.8 CAM69667.1 - 0.029 13.9 0.4 0.029 13.9 0.3 3.5 4 0 0 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NPV_P10 PF05531.7 CAM69667.1 - 0.042 14.1 3.3 3.6 7.9 0.3 3.9 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1515 PF07439.6 CAM69667.1 - 0.061 13.1 0.3 0.061 13.1 0.2 4.2 4 1 1 5 5 4 0 Protein of unknown function (DUF1515) bZIP_2 PF07716.10 CAM69667.1 - 0.092 12.5 0.3 0.092 12.5 0.2 5.4 7 0 0 7 7 6 0 Basic region leucine zipper HALZ PF02183.13 CAM69667.1 - 0.11 12.2 0.1 0.11 12.2 0.1 4.4 5 0 0 5 5 5 0 Homeobox associated leucine zipper Fib_alpha PF08702.5 CAM69667.1 - 0.2 11.7 15.8 6.6 6.8 0.2 4.7 4 1 1 5 5 5 0 Fibrinogen alpha/beta chain family bZIP_1 PF00170.16 CAM69667.1 - 0.26 11.2 0.1 0.26 11.2 0.1 4.1 5 0 0 5 5 4 0 bZIP transcription factor DUF972 PF06156.8 CAM69667.1 - 0.34 11.2 19.7 0.13 12.5 0.9 4.6 4 2 0 4 4 4 0 Protein of unknown function (DUF972) Striatin PF08232.7 CAM69667.1 - 0.45 10.8 20.0 0.1 12.8 3.3 3.9 3 1 0 3 3 3 0 Striatin family DUF4611 PF15387.1 CAM69667.1 - 0.84 9.8 5.7 0.32 11.1 0.2 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4611) BLOC1_2 PF10046.4 CAM69667.1 - 1.2 9.3 13.3 0.45 10.6 0.1 4.3 4 1 0 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_13 PF13166.1 CAM69667.1 - 1.3 7.3 18.8 0.66 8.3 2.4 3.3 3 1 0 3 3 3 0 AAA domain Hormone_1 PF00103.15 CAM69667.1 - 1.4 8.2 6.8 13 5.0 1.5 3.2 3 0 0 3 3 3 0 Somatotropin hormone family DivIC PF04977.10 CAM69667.1 - 3.1 7.3 21.2 0.69 9.4 0.4 5.5 5 1 1 6 6 6 0 Septum formation initiator AAA_23 PF13476.1 CAM69667.1 - 4 7.7 8.9 16 5.7 0.1 3.1 3 0 0 3 3 3 0 AAA domain DUF342 PF03961.8 CAM69667.1 - 4.5 5.5 11.3 0.81 8.0 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF342) Syntaxin-6_N PF09177.6 CAM69667.1 - 9.5 6.6 13.2 0.83 10.1 0.5 3.7 3 2 0 3 3 3 0 Syntaxin 6, N-terminal ADH_N PF08240.7 CAM69669.1 - 1.1e-13 50.9 0.3 1.2e-12 47.5 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 CAM69669.1 - 2.2e-12 47.9 0.0 6.1e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 CAM69669.1 - 4.8e-11 42.3 0.0 1.1e-09 37.9 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase SseB PF07179.7 CAM69670.1 - 6.6e-06 25.9 0.0 0.02 14.7 0.0 2.9 2 0 0 2 2 2 2 SseB protein N-terminal domain DUF4120 PF13496.1 CAM69671.1 - 0.048 13.6 1.3 0.11 12.4 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4120) EcoRII-N PF09217.5 CAM69671.1 - 0.13 11.8 2.3 0.3 10.6 0.1 2.0 1 1 1 2 2 2 0 Restriction endonuclease EcoRII, N-terminal LMBR1 PF04791.11 CAM69671.1 - 0.44 9.0 4.6 0.47 8.9 3.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Nexin_C PF08628.7 CAM69671.1 - 0.52 10.4 6.5 0.22 11.6 0.2 2.4 1 1 0 2 2 2 0 Sorting nexin C terminal Band_3_cyto PF07565.8 CAM69671.1 - 1.1 8.7 5.7 1.5 8.2 4.0 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain PYC_OADA PF02436.13 CAM69671.1 - 1.7 8.0 4.6 1.7 8.0 2.3 1.6 1 1 1 2 2 2 0 Conserved carboxylase domain Fumble PF03630.9 CAM69671.1 - 2 7.2 4.8 7.3 5.3 0.6 2.1 1 1 1 2 2 2 0 Fumble cNMP_binding PF00027.24 CAM69672.1 - 1.1e-14 53.9 0.0 1.4e-09 37.6 0.0 3.7 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Ku PF02735.11 CAM69673.1 - 9.6e-22 77.3 0.0 2.5e-21 75.9 0.0 1.6 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 CAM69673.1 - 7.6e-17 61.4 0.0 1.9e-10 40.5 0.0 2.7 3 0 0 3 3 3 2 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 CAM69673.1 - 0.001 19.5 0.5 0.1 13.1 0.2 2.5 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 CAM69673.1 - 0.016 14.7 0.0 0.036 13.5 0.0 1.7 1 0 0 1 1 1 0 SAP domain Ribosomal_L4 PF00573.17 CAM69676.2 - 1.2e-39 135.7 0.1 1.9e-39 135.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 CAM69676.2 - 2.8e-15 55.9 3.9 2.8e-15 55.9 2.7 2.3 2 1 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Ank_2 PF12796.2 CAM69678.1 - 6.7e-31 106.4 0.9 5.5e-11 42.6 0.0 4.3 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 CAM69678.1 - 5.5e-27 92.1 0.1 9.9e-07 28.2 0.0 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 CAM69678.1 - 9.6e-26 89.6 0.1 1.2e-10 41.5 0.0 4.4 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CAM69678.1 - 4.3e-23 79.0 0.0 0.00074 19.5 0.0 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 CAM69678.1 - 6.5e-18 64.3 1.2 6e-06 26.3 0.0 6.3 3 3 3 6 6 6 5 Ankyrin repeats (many copies) zf-HC2 PF13490.1 CAM69678.1 - 0.031 14.2 0.3 0.19 11.6 0.0 2.3 2 0 0 2 2 2 0 Putative zinc-finger PSP1 PF04468.7 CAM69680.1 - 1.1e-09 38.1 0.0 1.9e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Thioredoxin_8 PF13905.1 CAM69681.1 - 8.6e-11 41.8 0.0 1.6e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 CAM69681.1 - 0.00071 19.2 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CAM69681.1 - 0.036 13.6 0.0 0.062 12.8 0.0 1.3 1 0 0 1 1 1 0 Redoxin Thioredoxin_8 PF13905.1 CAM69682.1 - 8.8e-22 77.0 0.0 4.5e-17 61.9 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.16 CAM69682.1 - 2.3e-12 46.6 0.0 4.2e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CAM69682.1 - 9.2e-12 44.7 0.0 2.1e-11 43.5 0.0 1.5 2 0 0 2 2 2 1 Redoxin Thioredoxin PF00085.15 CAM69682.1 - 1e-07 31.5 0.0 3.4e-07 29.8 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 CAM69682.1 - 1.8e-06 28.0 0.0 5.6e-06 26.5 0.0 1.8 1 1 1 2 2 2 1 Thioredoxin-like domain TraF PF13728.1 CAM69682.1 - 6.2e-05 22.5 0.0 9.3e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.1 CAM69682.1 - 0.00013 21.9 0.0 0.00028 20.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 CAM69682.1 - 0.00017 21.1 0.0 0.00045 19.7 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin DUF4234 PF14018.1 CAM69682.1 - 0.94 9.2 9.9 1.8 8.3 6.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) Thioredoxin_8 PF13905.1 CAM69683.1 - 1.8e-24 85.6 0.0 2.4e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 CAM69683.1 - 6.6e-07 29.0 0.0 1.2e-06 28.2 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.15 CAM69683.1 - 1.5e-06 27.8 0.2 1.4e-05 24.6 0.1 2.0 1 1 1 2 2 2 1 Thioredoxin Redoxin PF08534.5 CAM69683.1 - 4.6e-06 26.2 0.0 4.9e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.1 CAM69683.1 - 2.3e-05 24.5 0.0 3e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.1 CAM69683.1 - 0.00039 19.9 0.0 0.0014 18.2 0.0 1.7 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.1 CAM69683.1 - 0.0027 17.6 0.0 0.004 17.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like DUF953 PF06110.6 CAM69683.1 - 0.021 14.2 0.0 4.8 6.6 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.1 CAM69683.1 - 0.042 13.4 0.1 0.16 11.5 0.0 1.8 1 1 0 1 1 1 0 Thioredoxin Thioredoxin_8 PF13905.1 CAM69684.1 - 4.6e-27 93.9 0.0 6.5e-27 93.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.15 CAM69684.1 - 1.7e-09 37.2 0.1 1.3e-06 28.0 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin AhpC-TSA PF00578.16 CAM69684.1 - 3.3e-09 36.4 0.0 4.7e-09 35.9 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.1 CAM69684.1 - 2.2e-08 34.2 0.0 3e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 CAM69684.1 - 4.8e-08 32.6 0.0 6.2e-08 32.3 0.0 1.3 1 1 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.1 CAM69684.1 - 3.6e-05 23.3 0.0 0.0021 17.6 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 CAM69684.1 - 0.00012 22.0 0.0 0.00022 21.2 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like TraF PF13728.1 CAM69684.1 - 0.0065 15.9 0.0 0.015 14.7 0.0 1.7 1 1 0 1 1 1 1 F plasmid transfer operon protein SCO1-SenC PF02630.9 CAM69684.1 - 0.018 14.6 0.1 0.027 14.0 0.0 1.4 1 1 0 1 1 1 0 SCO1/SenC DUF953 PF06110.6 CAM69684.1 - 0.025 14.0 0.1 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) EF-hand_7 PF13499.1 CAM69685.1 - 1.8e-05 24.7 0.1 0.00013 22.0 0.1 2.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 CAM69685.1 - 4.3e-05 23.0 0.0 0.00012 21.5 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CAM69685.1 - 6.2e-05 22.0 0.0 0.0002 20.4 0.0 1.9 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 CAM69685.1 - 0.00059 19.5 0.1 0.0014 18.3 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_9 PF14658.1 CAM69685.1 - 0.063 13.1 0.0 0.28 11.1 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain DUF3600 PF12207.3 CAM69685.1 - 0.066 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3600) Thioredoxin_8 PF13905.1 CAM69686.1 - 8.7e-05 22.5 0.0 2.8 8.1 0.0 3.3 3 0 0 3 3 3 3 Thioredoxin-like DUF572 PF04502.8 CAM69690.1 - 9e-16 57.9 16.4 4.5e-15 55.6 11.4 1.9 1 1 0 1 1 1 1 Family of unknown function (DUF572) DUF4557 PF15101.1 CAM69690.1 - 0.022 14.6 1.0 0.074 12.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Pol_alpha_B_N PF08418.5 CAM69690.1 - 0.68 9.4 9.1 0.092 12.2 1.0 2.3 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Relaxase PF03432.9 CAM69690.1 - 1.3 8.2 6.9 1.2 8.4 0.6 2.1 2 0 0 2 2 2 0 Relaxase/Mobilisation nuclease domain VIT1 PF01988.14 CAM69690.1 - 4.4 6.7 5.5 3.3 7.1 0.0 2.2 2 0 0 2 2 2 0 VIT family Sec16_C PF12931.2 CAM69691.2 - 1.6e-10 41.2 0.7 2.9e-10 40.3 0.5 1.4 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 HSP70 PF00012.15 CAM69692.1 - 1.5e-23 82.6 7.9 1.5e-22 79.3 0.1 2.4 1 1 1 2 2 2 2 Hsp70 protein TPR_11 PF13414.1 CAM69692.1 - 9.1e-17 60.4 2.8 1.9e-10 40.2 0.4 3.2 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 CAM69692.1 - 4.5e-11 41.8 0.1 2.5e-06 26.8 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 CAM69692.1 - 3.7e-10 38.9 0.4 4.2e-05 23.1 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CAM69692.1 - 5.2e-07 28.9 0.0 0.00025 20.5 0.0 3.4 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 CAM69692.1 - 2.8e-06 27.1 1.8 5.5e-05 23.0 0.0 3.3 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 CAM69692.1 - 3.8e-06 26.2 0.1 0.2 11.5 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 CAM69692.1 - 4.6e-05 23.1 0.3 0.0006 19.6 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 CAM69692.1 - 5.6e-05 23.6 0.1 0.00035 21.1 0.0 2.4 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 CAM69692.1 - 9.9e-05 22.4 0.7 0.00024 21.1 0.5 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 CAM69692.1 - 0.00022 21.4 0.6 0.0028 17.9 0.2 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 CAM69692.1 - 0.00032 20.6 0.1 0.0012 18.8 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc5 PF12862.2 CAM69692.1 - 0.0038 17.0 1.0 0.061 13.1 0.0 3.1 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_14 PF13428.1 CAM69692.1 - 0.0056 17.1 0.1 0.074 13.7 0.1 3.1 1 1 0 1 1 1 1 Tetratricopeptide repeat Cob_adeno_trans PF01923.13 CAM69692.1 - 0.084 12.6 5.8 0.18 11.5 0.8 2.9 2 1 1 3 3 3 0 Cobalamin adenosyltransferase TPR_6 PF13174.1 CAM69692.1 - 0.96 10.0 8.7 0.36 11.3 0.5 4.0 5 0 0 5 5 2 0 Tetratricopeptide repeat Lipase_3 PF01764.20 CAM69694.1 - 6e-26 90.7 0.0 2.7e-18 65.9 0.0 2.3 2 0 0 2 2 2 2 Lipase (class 3) MIG-14_Wnt-bd PF06664.7 CAM69694.1 - 3.3e-07 29.4 2.0 6.9e-07 28.3 1.4 1.4 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion DUF2974 PF11187.3 CAM69694.1 - 0.15 11.4 0.1 5.2 6.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) AAA_2 PF07724.9 CAM69695.1 - 7.7e-57 191.9 0.1 3.8e-54 183.1 0.0 3.4 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 CAM69695.1 - 2.8e-27 95.5 0.0 3e-15 56.6 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 CAM69695.1 - 2.8e-20 72.0 0.1 2.8e-20 72.0 0.0 3.2 4 0 0 4 4 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 CAM69695.1 - 3.6e-15 55.9 0.3 2e-10 40.5 0.0 3.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CAM69695.1 - 9.7e-12 45.2 7.9 0.0013 18.7 0.0 5.2 3 3 1 5 5 5 3 AAA ATPase domain Clp_N PF02861.15 CAM69695.1 - 2.8e-11 43.1 8.4 1.3e-05 25.0 1.4 3.6 4 0 0 4 4 3 2 Clp amino terminal domain AAA_22 PF13401.1 CAM69695.1 - 2.3e-10 40.7 0.1 0.00023 21.2 0.0 3.9 3 1 0 3 3 3 2 AAA domain AAA_14 PF13173.1 CAM69695.1 - 2e-08 34.1 0.0 0.0051 16.7 0.0 3.4 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.21 CAM69695.1 - 6.7e-08 32.1 0.0 4.3e-05 23.0 0.0 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_17 PF13207.1 CAM69695.1 - 7.7e-08 33.1 2.3 0.013 16.3 0.0 3.8 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 CAM69695.1 - 3.8e-07 29.6 0.0 0.017 14.5 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.7 CAM69695.1 - 2.9e-06 26.5 1.0 0.0018 17.4 0.0 4.2 5 0 0 5 5 4 1 Zeta toxin AAA_19 PF13245.1 CAM69695.1 - 2.9e-05 23.7 0.1 0.12 12.1 0.0 3.1 2 1 1 3 3 2 2 Part of AAA domain AAA_25 PF13481.1 CAM69695.1 - 3.3e-05 23.3 0.3 0.79 9.0 0.0 4.3 3 1 1 4 4 4 1 AAA domain Arch_ATPase PF01637.13 CAM69695.1 - 6.6e-05 22.7 7.8 1.1 8.9 0.0 4.4 3 2 1 5 5 5 2 Archaeal ATPase RuvB_N PF05496.7 CAM69695.1 - 7.1e-05 21.9 4.1 0.22 10.5 0.0 4.0 4 1 0 4 4 3 2 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 CAM69695.1 - 8.2e-05 22.3 0.2 0.11 12.1 0.0 3.9 5 0 0 5 5 4 1 NACHT domain AAA_18 PF13238.1 CAM69695.1 - 0.00021 21.5 6.1 0.25 11.6 0.0 4.3 4 1 1 5 5 3 2 AAA domain RNA_helicase PF00910.17 CAM69695.1 - 0.00088 19.4 0.2 1.4 9.1 0.0 3.2 4 0 0 4 4 2 1 RNA helicase DUF815 PF05673.8 CAM69695.1 - 0.0012 17.8 0.1 0.21 10.4 0.1 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 CAM69695.1 - 0.0013 18.6 0.1 0.6 9.9 0.0 3.8 4 0 0 4 4 3 1 AAA domain TIP49 PF06068.8 CAM69695.1 - 0.0013 17.5 0.1 0.22 10.1 0.0 3.0 2 1 1 3 3 3 1 TIP49 C-terminus Mg_chelatase PF01078.16 CAM69695.1 - 0.0014 17.8 0.1 3.5 6.7 0.0 3.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CAM69695.1 - 0.0025 17.4 0.1 1.3 8.6 0.0 3.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 CAM69695.1 - 0.003 17.4 0.8 0.53 10.1 0.0 3.9 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit AAA_10 PF12846.2 CAM69695.1 - 0.0031 16.9 0.2 1.2 8.5 0.0 3.4 2 1 1 3 3 3 1 AAA-like domain NTPase_1 PF03266.10 CAM69695.1 - 0.0047 16.6 0.3 3.3 7.3 0.0 3.5 3 0 0 3 3 3 1 NTPase DNA_pol3_delta2 PF13177.1 CAM69695.1 - 0.0052 16.4 0.0 0.2 11.3 0.0 3.2 2 1 0 2 2 2 1 DNA polymerase III, delta subunit DUF258 PF03193.11 CAM69695.1 - 0.0053 15.9 0.0 2.9 7.0 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 CAM69695.1 - 0.007 15.8 0.0 4 7.0 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.22 CAM69695.1 - 0.0099 16.1 1.9 12 6.1 0.0 4.0 4 1 0 4 4 3 0 ABC transporter AAA_28 PF13521.1 CAM69695.1 - 0.017 15.1 0.0 8.5 6.3 0.0 3.2 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 CAM69695.1 - 0.034 13.8 0.0 3.4 7.3 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 CAM69695.1 - 0.049 13.2 0.0 14 5.2 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MMR_HSR1 PF01926.18 CAM69695.1 - 0.06 13.3 0.0 1.6 8.7 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Miro PF08477.8 CAM69695.1 - 0.063 13.7 0.0 3.3 8.2 0.0 3.1 3 0 0 3 3 2 0 Miro-like protein DUF4524 PF15025.1 CAM69695.1 - 0.086 12.3 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4524) APG6 PF04111.7 CAM69695.1 - 2.2 7.2 11.1 4.2 6.3 7.7 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 CAM69695.1 - 2.5 5.8 6.5 4 5.1 4.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.1 CAM69695.1 - 7 6.9 25.0 9.6 6.4 0.0 4.2 2 2 0 2 2 1 0 AAA domain IncA PF04156.9 CAM69695.1 - 8.3 5.9 16.2 23 4.5 10.9 2.0 1 1 0 1 1 1 0 IncA protein DUF4140 PF13600.1 CAM69695.1 - 8.8 6.8 15.1 45 4.5 0.0 4.7 2 1 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) Lipase_3 PF01764.20 CAM69696.2 - 6.3e-27 93.9 0.0 1.4e-26 92.7 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) MIG-14_Wnt-bd PF06664.7 CAM69696.2 - 4e-06 25.8 9.7 4e-06 25.8 6.7 2.2 2 0 0 2 2 2 2 Wnt-binding factor required for Wnt secretion DSS1_SEM1 PF05160.8 CAM69697.1 - 0.00037 20.2 2.4 0.00037 20.2 1.6 1.8 2 0 0 2 2 2 1 DSS1/SEM1 family PRA-PH PF01503.12 CAM69698.1 - 0.015 15.5 0.0 1.6 9.0 0.0 3.3 2 1 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase DUF4034 PF13226.1 CAM69698.1 - 0.019 14.0 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4034) Carn_acyltransf PF00755.15 CAM69699.1 - 3.3e-90 302.8 0.0 3.8e-90 302.6 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Utp21 PF04192.7 CAM69699.1 - 0.049 12.7 0.0 0.079 12.0 0.0 1.2 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain RNA_pol_Rpc34 PF05158.7 CAM69700.1 - 4.3e-51 174.0 0.0 9e-50 169.6 0.0 2.6 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit TFIIE_alpha PF02002.12 CAM69700.1 - 0.017 14.5 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 TFIIE alpha subunit Rrf2 PF02082.15 CAM69700.1 - 0.12 12.5 0.8 5.7 7.1 0.1 2.9 3 0 0 3 3 3 0 Transcriptional regulator DUF1908 PF08926.6 CAM69700.1 - 0.14 10.9 0.1 0.3 9.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) RRM_1 PF00076.17 CAM69702.1 - 3.2e-33 113.1 0.0 7.1e-20 70.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM69702.1 - 2.8e-25 88.0 0.0 1.8e-13 50.2 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM69702.1 - 2.3e-18 65.7 0.0 9.3e-12 44.6 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CAM69702.1 - 0.0097 15.6 0.3 0.061 13.0 0.0 2.4 3 0 0 3 3 3 1 Limkain b1 RRM_3 PF08777.6 CAM69702.1 - 0.022 14.5 0.0 2.7 7.8 0.0 2.6 2 1 0 2 2 2 0 RNA binding motif Amastin PF07344.6 CAM69704.1 - 8.3e-49 165.1 13.1 9.8e-49 164.9 9.1 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF1467 PF07330.7 CAM69704.1 - 0.08 12.7 0.0 0.08 12.7 0.0 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1467) SP_C-Propep PF08999.5 CAM69704.1 - 7.1 6.1 6.9 1.6e+02 1.8 5.2 2.4 1 1 1 2 2 2 0 Surfactant protein C, N terminal propeptide Amastin PF07344.6 CAM69705.1 - 2.6e-52 176.5 9.7 2.6e-52 176.5 6.7 1.7 2 0 0 2 2 2 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CAM69705.1 - 0.71 9.5 11.8 0.72 9.5 5.5 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction SP_C-Propep PF08999.5 CAM69705.1 - 1.9 7.9 0.0 1.9 7.9 0.0 2.8 2 1 1 3 3 3 0 Surfactant protein C, N terminal propeptide RRM_1 PF00076.17 CAM69707.1 - 1.8e-23 81.9 0.0 1.1e-11 44.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM69707.1 - 7.6e-16 57.8 0.0 4.6e-07 29.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM69707.1 - 7e-05 22.5 0.0 0.0038 17.0 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAM69708.1 - 2e-25 88.2 0.0 1.6e-12 46.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM69708.1 - 5.5e-15 55.1 0.0 1.9e-07 30.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM69708.1 - 1.8e-07 30.9 0.0 1.4e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAM69709.2 - 9.6e-26 89.2 0.0 3.2e-14 52.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM69709.2 - 3.6e-20 71.6 0.4 9.1e-10 38.3 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM69709.2 - 4.4e-07 29.6 0.0 7.8e-05 22.4 0.0 3.0 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAM69711.1 - 5.8e-20 70.7 0.1 2.1e-13 49.6 0.1 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM69711.1 - 8.8e-16 57.6 0.6 1.4e-09 37.8 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 CAM69711.1 - 0.062 13.2 0.0 0.24 11.4 0.0 2.0 1 0 0 1 1 1 0 RNA binding domain RRM_5 PF13893.1 CAM69711.1 - 0.083 12.7 0.4 5.1 7.0 0.0 3.0 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-LYAR PF08790.6 CAM69712.1 - 9.8e-14 50.7 1.7 9.8e-14 50.7 1.2 2.1 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf-DNL PF05180.7 CAM69712.1 - 0.18 11.5 6.5 0.35 10.6 4.5 1.5 1 0 0 1 1 1 0 DNL zinc finger IBR PF01485.16 CAM69712.1 - 0.53 10.2 7.2 1.2 9.0 5.0 1.6 1 0 0 1 1 1 0 IBR domain Clat_adaptor_s PF01217.15 CAM69714.1 - 4.9e-49 165.7 1.2 5.8e-49 165.4 0.8 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MFS_1 PF07690.11 CAM69716.1 - 2.6e-21 75.7 23.5 1.4e-13 50.2 13.7 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 CAM69716.1 - 7.2e-13 48.3 18.7 7.2e-13 48.3 12.9 2.7 2 1 0 2 2 2 1 Nodulin-like Thioredoxin PF00085.15 CAM69717.1 - 2.2e-07 30.5 0.0 2.9e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin CENP-F_leu_zip PF10473.4 CAM69718.1 - 0.089 12.6 5.1 0.17 11.7 3.6 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4140 PF13600.1 CAM69718.1 - 0.13 12.7 4.0 0.36 11.3 2.8 1.8 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Mnd1 PF03962.10 CAM69718.1 - 0.33 10.6 2.7 0.78 9.3 1.9 1.6 1 0 0 1 1 1 0 Mnd1 family IncA PF04156.9 CAM69718.1 - 1.1 8.8 10.2 1.9 8.0 7.1 1.5 1 1 0 1 1 1 0 IncA protein FUSC PF04632.7 CAM69718.1 - 2.3 6.5 8.0 3.1 6.1 5.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family PI3_PI4_kinase PF00454.22 CAM69719.1 - 4.8e-31 108.0 0.0 1e-29 103.6 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 CAM69719.1 - 9.4e-16 57.5 0.3 2.6e-15 56.0 0.1 1.7 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) MIP-T3 PF10243.4 CAM69719.1 - 7.4 4.9 1.4 11 4.3 0.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Ank_5 PF13857.1 CAM69721.1 - 0.001 19.2 0.3 0.038 14.2 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CAM69721.1 - 0.0023 18.4 1.5 0.01 16.3 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 CAM69721.1 - 0.0029 17.9 0.7 0.0063 16.8 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 CAM69721.1 - 0.064 13.0 6.1 1.8 8.5 0.1 3.5 3 0 0 3 3 3 0 Ankyrin repeat Ank_3 PF13606.1 CAM69721.1 - 0.076 13.3 4.1 1 9.8 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeat Asn_synthase PF00733.16 CAM69723.1 - 1.9e-33 116.0 0.0 4.7e-18 65.6 0.0 3.3 3 0 0 3 3 3 3 Asparagine synthase Nodulin-like PF06813.8 CAM69724.1 - 5e-09 35.7 19.0 9.7e-09 34.8 9.7 3.1 2 1 0 2 2 2 1 Nodulin-like RabGAP-TBC PF00566.13 CAM69729.1 - 1.3e-42 145.7 0.0 1.7e-42 145.3 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Peptidase_M20 PF01546.23 CAM69730.1 - 6.1e-26 91.0 0.0 8.1e-26 90.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CAM69730.1 - 1.2e-18 66.8 0.0 1.9e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain WD40 PF00400.27 CAM69731.1 - 1.6e-07 30.9 0.0 0.00026 20.7 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat XPC-binding PF09280.6 CAM69732.1 - 5.3e-07 28.9 3.4 1.3e-06 27.7 2.3 1.7 1 1 0 1 1 1 1 XPC-binding domain UBA PF00627.26 CAM69732.1 - 1.2e-05 25.0 0.0 3.5e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain Prothymosin PF03247.9 CAM69732.1 - 1.5 8.9 20.2 0.96 9.6 6.0 2.6 2 0 0 2 2 2 0 Prothymosin/parathymosin family CENP-B_dimeris PF09026.5 CAM69732.1 - 7.3 6.9 17.0 5.4 7.3 5.7 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain EMP70 PF02990.11 CAM69735.1 - 3.7e-135 451.3 13.2 4.6e-135 451.0 9.2 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 SYS1 PF09801.4 CAM69737.1 - 1e-20 74.1 2.5 9.2e-19 67.8 0.5 2.2 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network PAP2 PF01569.16 CAM69737.1 - 0.9 9.2 4.8 0.17 11.5 0.3 1.9 2 0 0 2 2 2 0 PAP2 superfamily dsrm PF00035.20 CAM69738.1 - 6.6e-07 29.8 0.0 4 8.0 0.0 5.8 5 0 0 5 5 5 3 Double-stranded RNA binding motif COPI_C PF06957.6 CAM69738.1 - 0.45 8.9 1.9 0.75 8.2 1.3 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus RINGv PF12906.2 CAM69739.2 - 2e-11 43.7 8.4 4.3e-11 42.6 5.8 1.6 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 CAM69739.2 - 0.0016 18.2 7.1 0.0029 17.3 4.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING-like PF08746.6 CAM69739.2 - 0.46 10.5 6.3 0.82 9.7 4.4 1.4 1 0 0 1 1 1 0 RING-like domain ABC_tran PF00005.22 CAM69740.1 - 1.3e-27 96.7 0.0 2.6e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CAM69740.1 - 4.5e-10 39.9 0.4 3e-07 30.7 0.0 2.1 1 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 CAM69740.1 - 0.00095 18.4 0.2 0.013 14.7 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 CAM69740.1 - 0.0042 16.5 0.3 1.3 8.4 0.3 2.1 1 1 1 2 2 2 2 AAA-like domain SbcCD_C PF13558.1 CAM69740.1 - 0.013 15.4 0.7 0.12 12.3 0.2 2.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 CAM69740.1 - 0.014 15.1 0.1 0.2 11.4 0.1 2.6 2 0 0 2 2 2 0 Part of AAA domain DUF258 PF03193.11 CAM69740.1 - 0.02 14.0 0.0 0.039 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 CAM69740.1 - 0.042 13.2 0.0 0.89 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CAM69740.1 - 0.078 12.5 0.0 0.2 11.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain RuvB_N PF05496.7 CAM69740.1 - 0.087 11.8 0.1 0.15 11.0 0.1 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 CAM69740.1 - 0.09 12.4 0.4 0.34 10.5 0.1 1.9 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.1 CAM69740.1 - 0.12 13.1 0.0 0.27 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 CAM69740.1 - 0.25 11.5 1.1 8 6.6 0.8 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) 4HBT PF03061.17 CAM69741.1 - 5.1e-15 55.3 6.2 1.2e-09 38.1 0.4 2.8 3 0 0 3 3 3 2 Thioesterase superfamily 4HBT_2 PF13279.1 CAM69741.1 - 0.0023 18.3 1.7 0.25 11.7 0.1 2.7 1 1 0 2 2 2 2 Thioesterase-like superfamily MaoC_dehydratas PF01575.14 CAM69741.1 - 0.047 13.0 0.3 0.53 9.6 0.1 2.6 3 0 0 3 3 3 0 MaoC like domain MORN PF02493.15 CAM69742.1 - 5.9e-48 157.8 100.6 6.5e-07 28.7 0.9 21.7 22 0 0 22 22 22 18 MORN repeat MutS_V PF00488.16 CAM69743.1 - 2e-24 86.3 0.0 1e-16 61.0 0.0 2.5 2 0 0 2 2 2 2 MutS domain V MutS_III PF05192.13 CAM69743.1 - 6.9e-22 78.2 0.0 1.4e-21 77.2 0.0 1.5 1 1 0 1 1 1 1 MutS domain III AAA_29 PF13555.1 CAM69743.1 - 0.0079 15.7 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 CAM69743.1 - 0.064 12.4 0.0 0.17 11.0 0.0 1.6 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain PNRC PF15365.1 CAM69744.1 - 0.41 10.6 4.4 8.6 6.4 0.4 2.5 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator Flagellar_rod PF05149.7 CAM69748.1 - 7.6e-106 353.5 28.6 7.6e-106 353.5 19.8 2.8 2 1 1 3 3 3 2 Paraflagellar rod protein DUF1120 PF06551.7 CAM69748.1 - 0.13 12.5 1.1 0.36 11.1 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1120) Diphthamide_syn PF01866.12 CAM69749.1 - 1.4e-114 382.5 0.0 1.6e-114 382.2 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein BRCT PF00533.21 CAM69750.1 - 8.1e-11 41.9 0.0 0.0098 16.0 0.0 4.8 5 0 0 5 5 5 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CAM69750.1 - 3.3e-06 26.8 4.2 0.098 12.5 0.0 5.3 5 1 0 5 5 5 3 twin BRCT domain Ribosomal_S8 PF00410.14 CAM69751.1 - 2e-23 82.6 0.0 2.9e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Folliculin PF11704.3 CAM69752.1 - 2.6e-07 30.3 0.0 5.3e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Bac_surface_Ag PF01103.18 CAM69753.1 - 1.2e-18 67.6 0.6 1.5e-18 67.3 0.4 1.3 1 0 0 1 1 1 1 Surface antigen Pyr_redox_2 PF07992.9 CAM69754.1 - 1.1e-27 97.2 0.1 1.8e-27 96.5 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 CAM69754.1 - 1.5e-20 73.2 0.1 4.6e-20 71.6 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 CAM69754.1 - 3.3e-19 69.0 1.6 1.6e-16 60.4 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CAM69754.1 - 2.1e-12 47.5 0.8 2.8e-10 40.5 0.1 2.7 1 1 2 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CAM69754.1 - 1.3e-10 40.9 0.3 2.6e-10 39.9 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CAM69754.1 - 3.3e-07 29.7 2.0 0.039 12.9 0.1 3.3 2 1 1 3 3 3 3 FAD binding domain HI0933_like PF03486.9 CAM69754.1 - 7.5e-07 27.9 1.0 0.00067 18.2 0.3 3.3 3 0 0 3 3 3 1 HI0933-like protein K_oxygenase PF13434.1 CAM69754.1 - 5.2e-06 25.5 0.0 2.8e-05 23.2 0.0 2.0 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 CAM69754.1 - 1.9e-05 23.7 5.6 0.05 12.4 1.9 3.4 3 1 0 3 3 3 2 Glucose inhibited division protein A DAO PF01266.19 CAM69754.1 - 2.3e-05 23.4 6.5 0.0027 16.6 0.2 3.1 2 2 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.12 CAM69754.1 - 3e-05 23.2 0.2 0.0041 16.2 0.0 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 CAM69754.1 - 0.00058 18.8 1.4 0.00058 18.8 1.0 3.0 2 1 1 3 3 3 1 FAD binding domain ThiF PF00899.16 CAM69754.1 - 0.00079 19.2 0.1 0.0037 17.0 0.0 2.1 2 0 0 2 2 2 1 ThiF family 3HCDH_N PF02737.13 CAM69754.1 - 0.002 17.7 0.0 0.0044 16.6 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 CAM69754.1 - 0.0025 17.3 0.1 0.24 10.9 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.1 CAM69754.1 - 0.0028 17.6 4.8 0.14 12.1 0.6 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.14 CAM69754.1 - 0.011 14.8 0.1 0.039 13.0 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 CAM69754.1 - 0.17 10.7 0.5 2.4 6.9 0.0 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein Shikimate_DH PF01488.15 CAM69754.1 - 0.26 11.3 1.8 0.9 9.6 0.2 2.5 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase NYD-SP28_assoc PF14775.1 CAM69755.1 - 0.053 13.2 1.6 0.25 11.0 1.1 2.2 1 0 0 1 1 1 0 Sperm tail C-terminal domain XPG_N PF00752.12 CAM69755.1 - 0.067 13.4 0.1 0.21 11.8 0.0 1.8 2 0 0 2 2 2 0 XPG N-terminal domain Snapin_Pallidin PF14712.1 CAM69755.1 - 0.11 12.7 22.8 0.11 12.8 0.5 4.6 2 2 2 4 4 4 0 Snapin/Pallidin Borrelia_REV PF03978.8 CAM69755.1 - 0.22 11.2 2.3 11 5.7 0.0 3.1 2 1 1 3 3 3 0 Borrelia burgdorferi REV protein Hemerythrin PF01814.18 CAM69755.1 - 0.28 11.3 9.7 3.8 7.6 2.8 3.1 1 1 2 3 3 3 0 Hemerythrin HHE cation binding domain DUF2730 PF10805.3 CAM69755.1 - 0.29 10.8 8.6 1.8 8.3 0.1 3.6 2 2 1 4 4 4 0 Protein of unknown function (DUF2730) Myb_DNA-bind_4 PF13837.1 CAM69755.1 - 0.98 9.5 6.0 0.32 11.1 1.6 2.1 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF342 PF03961.8 CAM69755.1 - 1.3 7.3 12.9 0.38 9.1 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Baculo_PEP_C PF04513.7 CAM69755.1 - 1.5 8.6 10.0 0.28 11.0 0.4 3.2 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.6 CAM69755.1 - 1.9 5.8 11.1 1.5 6.2 6.9 1.3 1 1 0 1 1 1 0 Prominin Bacillus_HBL PF05791.6 CAM69755.1 - 3.8 6.8 12.4 0.16 11.3 1.9 2.6 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Cep57_CLD PF14073.1 CAM69755.1 - 4 7.2 29.4 0.048 13.4 13.3 2.1 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 WXG100 PF06013.7 CAM69755.1 - 4.4 7.3 14.0 0.97 9.4 0.6 3.8 2 1 2 4 4 4 0 Proteins of 100 residues with WXG DUF1993 PF09351.5 CAM69755.1 - 4.5 7.1 10.1 0.89 9.4 3.5 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1993) PIH1 PF08190.7 CAM69756.1 - 2.2e-12 47.0 0.1 2.9e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 zf-met2 PF12907.2 CAM69758.1 - 0.00029 20.7 0.6 0.00067 19.5 0.4 1.6 1 1 0 1 1 1 1 Zinc-binding DnaJ PF00226.26 CAM69760.1 - 1.5e-08 34.2 0.0 3.2e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Zn_ribbon_recom PF13408.1 CAM69761.1 - 0.029 14.6 0.7 0.057 13.6 0.5 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zinc_ribbon_2 PF13240.1 CAM69761.1 - 0.08 12.4 0.1 0.2 11.1 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zf-HIT PF04438.11 CAM69761.1 - 0.6 9.7 3.3 0.24 11.0 0.3 1.7 2 0 0 2 2 2 0 HIT zinc finger BAF1_ABF1 PF04684.8 CAM69761.1 - 1 8.1 5.3 0.14 11.0 0.4 1.8 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Cnd1_N PF12922.2 CAM69762.1 - 0.053 13.1 0.3 5.5 6.5 0.0 2.3 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term EF-hand_7 PF13499.1 CAM69764.1 - 3.5e-08 33.4 0.1 0.93 9.6 0.0 4.1 2 2 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 CAM69764.1 - 0.0015 18.2 0.0 3.3 7.8 0.0 4.1 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.27 CAM69764.1 - 0.0034 16.5 0.5 0.44 9.9 0.1 3.5 4 0 0 4 4 4 1 EF hand PPTA PF01239.17 CAM69766.1 - 3.3e-17 61.0 19.1 6.1e-07 28.5 0.1 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Fumerase PF05681.9 CAM69767.1 - 7.6e-86 287.5 0.0 9.8e-86 287.1 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Fumerase_C PF05683.7 CAM69767.1 - 2.4e-81 271.7 0.0 3.8e-81 271.1 0.0 1.3 1 0 0 1 1 1 1 Fumarase C-terminus PPR_2 PF13041.1 CAM69772.1 - 6e-06 26.1 0.0 0.036 14.0 0.0 4.1 4 1 1 5 5 5 2 PPR repeat family PPR PF01535.15 CAM69772.1 - 0.00019 21.1 0.1 3.3 7.8 0.0 4.3 4 0 0 4 4 4 2 PPR repeat PPR_3 PF13812.1 CAM69772.1 - 0.0029 17.7 5.1 76 3.9 0.0 6.2 6 1 0 6 6 6 0 Pentatricopeptide repeat domain Pkinase PF00069.20 CAM69773.1 - 1.6e-74 250.3 0.0 2.2e-74 249.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM69773.1 - 4.4e-40 137.3 0.0 6.4e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM69773.1 - 2.2e-06 26.8 0.0 1e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 CAM69773.1 - 7.7e-06 25.3 0.3 0.00024 20.4 0.0 2.1 1 1 1 2 2 2 1 RIO1 family Kdo PF06293.9 CAM69773.1 - 0.00042 19.4 0.0 0.00077 18.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CAM69773.1 - 0.00081 19.1 0.2 0.073 12.7 0.1 3.0 3 0 0 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CAM69773.1 - 0.13 11.8 0.1 0.5 9.9 0.1 1.8 1 1 0 1 1 1 0 Choline/ethanolamine kinase adh_short PF00106.20 CAM69784.1 - 3.6e-07 30.2 0.1 7.2e-07 29.2 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase AAA_12 PF13087.1 CAM69785.1 - 6e-33 113.9 0.0 9.6e-33 113.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CAM69785.1 - 1.2e-18 67.5 0.0 1.1e-17 64.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CAM69785.1 - 1.8e-08 34.2 0.6 0.0016 18.0 0.0 3.4 3 0 0 3 3 3 2 AAA domain PhoH PF02562.11 CAM69785.1 - 0.00021 20.5 0.0 0.096 11.8 0.0 3.0 3 0 0 3 3 3 1 PhoH-like protein AAA_19 PF13245.1 CAM69785.1 - 0.00074 19.2 0.0 0.00074 19.2 0.0 3.7 4 0 0 4 4 4 1 Part of AAA domain AAA_22 PF13401.1 CAM69785.1 - 0.0017 18.5 1.0 0.52 10.4 0.0 4.2 5 0 0 5 5 5 1 AAA domain Viral_helicase1 PF01443.13 CAM69785.1 - 0.0078 15.7 0.9 2.9 7.3 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 CAM69785.1 - 0.012 14.5 0.1 0.034 13.1 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 CAM69785.1 - 0.018 15.8 0.0 0.054 14.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain CSD PF00313.17 CAM69785.1 - 0.29 10.9 0.1 0.66 9.7 0.0 1.6 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain DUF4139 PF13598.1 CAM69786.1 - 8.6e-66 222.4 0.0 1.3e-65 221.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) UDP-g_GGTase PF06427.6 CAM69787.2 - 8.1e-64 214.7 0.0 3.4e-63 212.7 0.0 1.9 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 CAM69787.2 - 1.8e-05 24.2 0.1 3.4e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 LRR_4 PF12799.2 CAM69788.1 - 5.6e-13 48.1 17.8 0.0014 18.2 0.0 6.6 4 2 3 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM69788.1 - 1.9e-09 37.0 14.1 0.0058 16.3 1.1 4.6 2 1 3 5 5 5 5 Leucine rich repeat LRR_1 PF00560.28 CAM69788.1 - 1e-07 30.9 22.2 1.2 9.4 0.1 9.0 7 3 2 9 9 9 4 Leucine Rich Repeat LRR_7 PF13504.1 CAM69788.1 - 2e-06 27.0 20.9 7.9 7.1 0.0 9.6 9 0 0 9 9 9 3 Leucine rich repeat LRR_6 PF13516.1 CAM69788.1 - 0.00042 20.0 22.7 2.3 8.5 0.0 8.3 9 0 0 9 9 9 3 Leucine Rich repeat FNIP PF05725.7 CAM69788.1 - 0.00048 20.0 7.4 3.5 7.6 0.1 5.0 3 1 2 5 5 5 3 FNIP Repeat ERG2_Sigma1R PF04622.7 CAM69789.1 - 3.1e-70 235.7 0.6 3.6e-70 235.6 0.4 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Pkinase PF00069.20 CAM69790.1 - 4.9e-43 147.1 0.0 4.9e-41 140.6 0.0 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAM69790.1 - 1.3e-17 63.7 0.0 1.1e-15 57.4 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CAM69790.1 - 0.18 10.7 0.0 0.83 8.5 0.0 1.9 2 0 0 2 2 2 0 Kinase-like GDI PF00996.13 CAM69791.1 - 2.8e-174 579.5 0.0 3.2e-174 579.3 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor DTW PF03942.10 CAM69792.1 - 1.1e-16 60.6 0.4 3.5e-16 59.0 0.3 1.9 1 1 0 1 1 1 1 DTW domain DUF4379 PF14311.1 CAM69793.1 - 2.4e-41 139.3 17.3 6.1e-15 54.7 0.3 3.4 3 0 0 3 3 3 3 Domain of unknown function (DUF4379) SprT-like PF10263.4 CAM69793.1 - 0.18 11.4 5.5 6.2 6.4 0.1 3.0 3 0 0 3 3 3 0 SprT-like family Lar_restr_allev PF14354.1 CAM69793.1 - 0.24 11.7 12.9 0.55 10.5 0.2 4.7 3 1 1 4 4 4 0 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.5 CAM69793.1 - 1.4 8.8 15.4 0.65 9.9 0.3 4.1 3 2 0 3 3 3 0 Zinc ribbon domain DUF2072 PF09845.4 CAM69793.1 - 2.7 7.9 8.0 0.13 12.2 0.6 2.5 2 1 1 3 3 3 0 Zn-ribbon containing protein (DUF2072) Dynamin_M PF01031.15 CAM69795.1 - 2.9e-91 305.3 0.4 6.8e-91 304.1 0.3 1.6 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 CAM69795.1 - 3.9e-50 169.9 0.1 9.1e-50 168.7 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 CAM69795.1 - 1.1e-23 82.9 0.7 3.8e-23 81.2 0.2 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 CAM69795.1 - 0.00015 21.6 0.4 0.0011 18.9 0.2 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CAM69795.1 - 0.016 14.4 0.3 3.7 6.7 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B cIII PF08134.6 CAM69795.1 - 0.023 14.2 0.9 0.14 11.7 0.0 2.4 2 0 0 2 2 2 0 cIII protein family Miro PF08477.8 CAM69795.1 - 0.032 14.7 0.0 0.069 13.6 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein LRR_9 PF14580.1 CAM69796.1 - 5.6e-13 48.8 0.3 8.7e-13 48.2 0.2 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 CAM69796.1 - 1.6e-11 43.5 3.0 6.3e-05 22.4 0.1 3.8 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM69796.1 - 6.6e-07 28.9 6.1 1.1e-06 28.2 0.9 2.9 3 0 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.28 CAM69796.1 - 0.00036 20.1 3.2 8 6.9 0.2 4.4 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.1 CAM69796.1 - 0.0034 17.2 5.4 2 8.7 0.1 4.3 3 1 2 5 5 5 1 Leucine Rich repeat ApbA PF02558.11 CAM69798.1 - 0.01 15.3 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 CAM69798.1 - 0.012 15.3 0.5 0.066 12.9 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 CAM69798.1 - 0.065 13.3 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Peptidase_M1 PF01433.15 CAM69799.1 - 9e-95 318.0 0.0 1.6e-94 317.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 CAM69799.1 - 9.5e-19 67.7 0.1 1.3e-18 67.2 0.1 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 CAM69799.1 - 8.1e-13 48.5 0.1 1.9e-12 47.3 0.1 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily TctC PF03401.9 CAM69799.1 - 0.063 12.1 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter family receptor Takusan PF04822.8 CAM69800.1 - 0.01 15.5 1.6 0.25 11.1 0.2 2.9 2 0 0 2 2 2 0 Takusan IncA PF04156.9 CAM69800.1 - 0.012 15.2 7.5 0.012 15.2 5.2 4.2 5 0 0 5 5 5 0 IncA protein ADIP PF11559.3 CAM69800.1 - 0.012 15.4 3.8 0.012 15.4 2.6 3.8 4 0 0 4 4 4 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.6 CAM69800.1 - 0.051 13.3 27.6 1.4 8.6 0.3 3.8 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) FH2 PF02181.18 CAM69800.1 - 0.052 12.4 8.8 0.39 9.5 0.2 3.6 4 0 0 4 4 4 0 Formin Homology 2 Domain Filament PF00038.16 CAM69800.1 - 0.25 10.7 26.3 0.038 13.4 2.9 3.5 4 0 0 4 4 4 0 Intermediate filament protein Tropomyosin PF00261.15 CAM69800.1 - 0.3 10.1 24.8 0.021 13.9 1.8 3.5 4 0 0 4 4 4 0 Tropomyosin HALZ PF02183.13 CAM69800.1 - 0.35 10.6 15.2 0.39 10.4 0.6 4.5 5 0 0 5 5 5 0 Homeobox associated leucine zipper DUF4600 PF15372.1 CAM69800.1 - 0.5 10.5 14.9 1.2 9.4 1.7 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4600) FlxA PF14282.1 CAM69800.1 - 0.76 9.7 28.1 2.5 8.0 1.6 4.0 4 0 0 4 4 4 0 FlxA-like protein Myosin_tail_1 PF01576.14 CAM69800.1 - 0.79 7.3 26.4 0.69 7.5 13.5 3.0 2 1 0 2 2 2 0 Myosin tail Fib_alpha PF08702.5 CAM69800.1 - 1.6 8.8 13.3 0.53 10.4 0.7 3.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.7 CAM69800.1 - 2.9 7.7 9.6 12 5.7 0.6 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) Phage_GP20 PF06810.6 CAM69800.1 - 3.8 6.9 22.9 1 8.7 1.0 3.6 4 0 0 4 4 4 0 Phage minor structural protein GP20 DUF2968 PF11180.3 CAM69800.1 - 4.9 6.4 33.6 0.015 14.7 6.3 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2968) DCX PF03607.12 CAM69801.1 - 7.6e-06 25.4 0.1 0.00014 21.3 0.0 2.3 2 0 0 2 2 2 1 Doublecortin Msg2_C PF12373.3 CAM69801.1 - 0.44 9.8 3.4 1 8.6 2.3 1.6 1 0 0 1 1 1 0 Major surface glycoprotein 2 C terminal PAP_central PF04928.12 CAM69802.1 - 6.9e-42 143.0 0.0 9.4e-42 142.5 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 CAM69802.1 - 2.2e-05 24.0 0.0 4e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 CAM69802.1 - 0.025 14.9 0.0 0.046 14.0 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain GAS PF13851.1 CAM69803.1 - 0.16 11.1 3.8 0.54 9.4 2.6 2.0 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding SAM_1 PF00536.25 CAM69805.1 - 0.00012 22.1 0.0 0.00031 20.8 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) FANCI_S1-cap PF14674.1 CAM69805.1 - 0.02 14.9 0.0 4.3 7.4 0.0 3.1 2 0 0 2 2 2 0 FANCI solenoid 1 cap SAM_2 PF07647.12 CAM69805.1 - 0.024 14.4 0.0 0.05 13.4 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DnaB_bind PF10410.4 CAM69805.1 - 0.047 13.6 6.6 9.8 6.2 0.0 4.8 4 0 0 4 4 4 0 DnaB-helicase binding domain of primase Sld5 PF05916.6 CAM69806.1 - 6e-07 29.7 0.0 1.1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein Acyltransferase PF01553.16 CAM69807.1 - 1.9e-08 33.8 0.1 4.2e-08 32.7 0.0 1.6 2 0 0 2 2 2 1 Acyltransferase Vezatin PF12632.2 CAM69807.1 - 0.48 9.4 3.4 0.84 8.6 2.3 1.4 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes Acyltransferase PF01553.16 CAM69808.1 - 2e-08 33.7 0.0 3.2e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase UCH PF00443.24 CAM69810.1 - 2.3e-49 167.9 0.1 7.3e-49 166.2 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CAM69810.1 - 9e-17 61.4 0.0 3.3e-16 59.5 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CAM69810.1 - 3.3e-16 59.1 6.6 3.3e-16 59.1 4.6 3.6 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 CAM69810.1 - 6.9e-07 28.9 0.1 1.7e-06 27.6 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 CAM69810.1 - 0.08 12.4 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain ECH PF00378.15 CAM69811.1 - 3.3e-69 232.7 1.0 4e-69 232.4 0.7 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 CAM69811.1 - 0.0022 17.8 0.0 0.026 14.2 0.0 2.2 2 0 0 2 2 2 1 Peptidase family S49 ECH_C PF13766.1 CAM69811.1 - 0.015 15.4 0.2 0.034 14.3 0.1 1.6 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region Pkinase PF00069.20 CAM69812.1 - 2.8e-53 180.7 0.0 3.9e-53 180.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM69812.1 - 7.6e-35 120.2 0.0 1.2e-34 119.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CAM69812.1 - 0.00015 21.5 0.0 0.12 12.1 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CAM69812.1 - 0.095 11.4 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase GET2 PF08690.5 CAM69813.1 - 0.0012 18.1 0.1 0.0046 16.2 0.0 1.9 2 1 1 3 3 3 1 GET complex subunit GET2 GrpE PF01025.14 CAM69813.1 - 0.11 11.9 1.9 1.3 8.5 0.0 2.5 2 1 0 2 2 2 0 GrpE NAP PF00956.13 CAM69814.1 - 6.7e-19 67.9 3.4 4.2e-17 62.0 2.4 2.0 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) Phage_Mu_Gam PF07352.7 CAM69814.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein COQ7 PF03232.8 CAM69815.1 - 7.8e-62 207.7 0.4 9.1e-62 207.5 0.3 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Peptidase_M18 PF02127.10 CAM69816.1 - 7e-156 519.0 0.0 8e-156 518.8 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 CAM69816.1 - 1.3e-09 37.2 0.1 3.7e-07 29.2 0.0 2.2 1 1 0 1 1 1 1 M42 glutamyl aminopeptidase Ribosomal_L39 PF00832.15 CAM69817.1 - 2.3e-19 68.5 14.3 2.6e-19 68.3 9.9 1.0 1 0 0 1 1 1 1 Ribosomal L39 protein Methyltransf_FA PF12248.3 CAM69817.1 - 0.081 12.9 0.0 0.089 12.8 0.0 1.1 1 0 0 1 1 1 0 Farnesoic acid 0-methyl transferase Kinesin PF00225.18 CAM69818.1 - 8.7e-93 310.6 0.0 1.1e-92 310.2 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Kinesin PF00225.18 CAM69819.1 - 7.1e-93 310.9 0.1 1e-92 310.4 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain C2 PF00168.25 CAM69819.1 - 0.00014 21.6 0.0 0.0023 17.7 0.0 2.7 2 0 0 2 2 2 1 C2 domain GAS PF13851.1 CAM69819.1 - 0.0099 15.0 2.4 0.023 13.9 1.7 1.5 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF972 PF06156.8 CAM69819.1 - 0.11 12.8 2.4 5.9 7.2 0.7 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) NIF PF03031.13 CAM69820.1 - 4.7e-30 104.3 0.0 7.6e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF705 PF05152.7 CAM69820.1 - 0.00089 18.3 0.1 0.0013 17.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF705) Acyltransferase PF01553.16 CAM69821.1 - 1e-10 41.1 0.0 2e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase PDEase_I PF00233.14 CAM69824.1 - 3.2e-61 207.0 1.6 5.1e-61 206.4 1.1 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Pec_lyase_N PF04431.8 CAM69824.1 - 5.1 7.2 5.8 15 5.7 0.7 2.7 2 0 0 2 2 2 0 Pectate lyase, N terminus HSP20 PF00011.16 CAM69825.1 - 4.2e-17 61.8 0.0 5.3e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family PapC_N PF13954.1 CAM69825.1 - 0.0024 17.4 0.0 0.0034 16.9 0.0 1.2 1 0 0 1 1 1 1 PapC N-terminal domain Ribosomal_L13e PF01294.13 CAM69826.1 - 1.7e-54 184.0 5.5 1.7e-54 184.0 3.8 1.8 1 1 1 2 2 2 1 Ribosomal protein L13e PTPS PF01242.14 CAM69826.1 - 0.054 13.1 0.0 0.079 12.6 0.0 1.2 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase Ribosomal_L13e PF01294.13 CAM69827.1 - 1.7e-54 184.0 5.5 1.7e-54 184.0 3.8 1.8 1 1 1 2 2 2 1 Ribosomal protein L13e PTPS PF01242.14 CAM69827.1 - 0.054 13.1 0.0 0.079 12.6 0.0 1.2 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase DUF2733 PF10813.3 CAM69828.1 - 6.5 6.4 5.2 1.9 8.1 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2733) HCV_NS5a PF01506.14 CAM69828.1 - 8.1 6.2 9.8 8.6 6.1 1.0 2.3 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a protein membrane anchor Pkinase PF00069.20 CAM69829.1 - 9.7e-46 156.0 0.0 1.4e-45 155.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM69829.1 - 2.3e-36 125.1 0.0 2.9e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CAM69829.1 - 0.0079 15.0 0.1 0.014 14.2 0.1 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase zf-B_box PF00643.19 CAM69829.1 - 0.011 15.6 4.9 0.011 15.6 3.4 4.0 3 1 1 4 4 4 0 B-box zinc finger APH PF01636.18 CAM69829.1 - 0.013 15.2 0.3 0.026 14.2 0.2 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 CAM69829.1 - 0.021 13.9 0.0 0.036 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CAM69829.1 - 0.089 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase AAA PF00004.24 CAM69830.1 - 2.8e-40 137.5 0.0 7e-40 136.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 CAM69830.1 - 6.4e-27 93.2 0.2 1.7e-26 91.8 0.2 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 CAM69830.1 - 3e-20 71.8 1.8 9.4e-20 70.2 1.0 2.1 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 CAM69830.1 - 3e-06 28.0 0.3 1.9e-05 25.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.9 CAM69830.1 - 7.1e-06 26.0 0.0 2e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CAM69830.1 - 1e-05 25.6 0.3 0.00024 21.2 0.0 2.8 2 1 0 2 2 1 1 AAA domain AAA_25 PF13481.1 CAM69830.1 - 1.2e-05 24.7 0.3 0.16 11.3 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 CAM69830.1 - 2.4e-05 24.4 0.0 0.00045 20.2 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 CAM69830.1 - 7.1e-05 22.5 0.0 0.0004 20.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 CAM69830.1 - 0.00016 21.1 0.0 0.00031 20.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 CAM69830.1 - 0.00027 20.8 0.0 0.00088 19.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 CAM69830.1 - 0.00032 20.3 0.2 0.0078 15.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 CAM69830.1 - 0.00053 18.9 0.0 0.00088 18.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 CAM69830.1 - 0.00071 19.4 0.0 0.0023 17.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CAM69830.1 - 0.00075 18.6 0.0 0.0016 17.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 CAM69830.1 - 0.0017 17.1 0.0 0.0026 16.5 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus USP8_dimer PF08969.6 CAM69830.1 - 0.0058 16.5 3.2 0.017 15.0 2.2 1.8 1 0 0 1 1 1 1 USP8 dimerisation domain RNA_helicase PF00910.17 CAM69830.1 - 0.0076 16.4 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 RNA helicase PPV_E1_C PF00519.12 CAM69830.1 - 0.011 14.4 0.0 0.017 13.7 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase AAA_18 PF13238.1 CAM69830.1 - 0.012 15.9 0.1 0.039 14.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CAM69830.1 - 0.016 14.8 1.7 0.75 9.4 0.0 2.8 2 2 1 3 3 3 0 Archaeal ATPase AAA_19 PF13245.1 CAM69830.1 - 0.018 14.7 0.0 0.062 13.0 0.0 1.9 2 0 0 2 2 1 0 Part of AAA domain Zeta_toxin PF06414.7 CAM69830.1 - 0.023 13.8 0.0 0.051 12.6 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Viral_helicase1 PF01443.13 CAM69830.1 - 0.024 14.1 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.16 CAM69830.1 - 0.038 13.1 0.0 0.076 12.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ResIII PF04851.10 CAM69830.1 - 0.044 13.6 0.0 0.41 10.4 0.0 2.1 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit CPT PF07931.7 CAM69830.1 - 0.047 13.3 0.0 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Parvo_NS1 PF01057.12 CAM69830.1 - 0.058 12.2 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.11 CAM69830.1 - 0.072 12.3 0.0 0.18 10.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 CAM69830.1 - 0.083 12.5 0.0 0.65 9.6 0.0 2.1 1 1 2 3 3 3 0 NACHT domain Sigma54_activat PF00158.21 CAM69830.1 - 0.14 11.5 0.0 0.42 10.0 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_21 PF13304.1 CAM69830.1 - 0.16 11.8 0.8 3.3 7.5 0.0 2.6 2 1 0 3 3 2 0 AAA domain PFK PF00365.15 CAM69831.1 - 1.8e-37 128.8 1.2 2.6e-37 128.3 0.8 1.2 1 0 0 1 1 1 1 Phosphofructokinase NAD_kinase PF01513.16 CAM69831.1 - 0.00031 19.6 0.0 0.00061 18.6 0.0 1.4 1 0 0 1 1 1 1 ATP-NAD kinase DUF3813 PF12758.2 CAM69831.1 - 0.14 12.3 0.1 0.37 10.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) zf-MIZ PF02891.15 CAM69832.1 - 4.7e-09 35.6 1.5 3.1e-08 33.0 0.0 2.8 3 0 0 3 3 3 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 CAM69832.1 - 0.063 12.8 0.2 0.15 11.6 0.1 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit TPR_19 PF14559.1 CAM69835.1 - 8.5e-21 74.0 25.3 1.3e-06 28.6 0.5 9.0 7 3 3 10 10 10 8 Tetratricopeptide repeat TPR_14 PF13428.1 CAM69835.1 - 1e-18 66.0 37.5 0.0016 18.9 0.1 10.3 9 1 2 11 11 9 6 Tetratricopeptide repeat TPR_11 PF13414.1 CAM69835.1 - 2.9e-15 55.6 23.8 0.004 16.7 0.0 9.7 9 1 1 10 10 10 5 TPR repeat TPR_16 PF13432.1 CAM69835.1 - 6.4e-14 52.1 45.5 5.4e-06 26.9 1.0 10.7 9 2 2 11 11 10 4 Tetratricopeptide repeat TPR_17 PF13431.1 CAM69835.1 - 9.4e-07 28.5 5.9 19 5.7 0.0 7.8 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_12 PF13424.1 CAM69835.1 - 2.3e-06 27.4 33.9 0.05 13.5 1.0 8.5 8 1 1 9 9 9 5 Tetratricopeptide repeat Apc3 PF12895.2 CAM69835.1 - 3.9e-06 26.8 19.0 0.054 13.6 0.1 6.1 6 1 1 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 CAM69835.1 - 4.6e-05 23.0 33.1 0.076 12.9 0.0 11.0 13 0 0 13 13 11 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.5 CAM69835.1 - 0.0015 18.0 12.8 0.038 13.4 0.8 4.8 3 1 1 4 4 4 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_6 PF13174.1 CAM69835.1 - 0.0064 16.8 17.5 0.84 10.2 0.0 8.5 9 0 0 9 9 9 1 Tetratricopeptide repeat NatB_MDM20 PF09797.4 CAM69835.1 - 0.0082 14.9 0.7 0.017 13.8 0.2 1.7 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_4 PF07721.9 CAM69835.1 - 0.01 16.1 43.2 2.8 8.6 0.6 9.7 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_20 PF14561.1 CAM69835.1 - 0.012 15.6 7.4 0.027 14.5 0.2 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Topoisom_bac PF01131.15 CAM69835.1 - 0.013 14.3 0.2 0.024 13.4 0.1 1.3 1 0 0 1 1 1 0 DNA topoisomerase TPR_1 PF00515.23 CAM69835.1 - 0.32 10.6 0.0 0.32 10.6 0.0 7.2 10 0 0 10 10 10 0 Tetratricopeptide repeat DUF4586 PF15239.1 CAM69836.1 - 3.6e-68 230.3 13.4 4.5e-68 230.0 9.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) Pkinase PF00069.20 CAM69837.1 - 1.9e-63 214.0 0.0 2.9e-63 213.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM69837.1 - 9.8e-45 152.6 0.0 1.8e-44 151.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM69837.1 - 1.6e-06 27.2 0.0 2.6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CAM69837.1 - 0.08 12.6 0.0 7.3 6.2 0.1 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Tachykinin PF02202.11 CAM69838.1 - 0.12 12.1 0.8 29 4.7 0.1 3.1 2 0 0 2 2 2 0 Tachykinin family Proteasom_PSMB PF10508.4 CAM69839.1 - 0.0093 14.2 0.4 0.37 9.0 0.0 2.6 3 1 0 3 3 3 2 Proteasome non-ATPase 26S subunit RIX1 PF08167.7 CAM69839.1 - 0.19 11.4 2.4 0.97 9.0 0.2 2.7 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis Cnd3 PF12719.2 CAM69840.2 - 3.4e-41 141.1 2.7 6.4e-41 140.2 0.1 2.6 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.17 CAM69840.2 - 2.8e-05 23.8 8.8 4.8 7.5 0.0 6.8 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 CAM69840.2 - 4.3e-05 23.6 12.9 0.011 16.0 0.1 5.7 5 2 1 6 6 6 2 HEAT repeats Helicase_C_2 PF13307.1 CAM69841.1 - 6.6e-50 169.3 0.0 1.8e-49 167.8 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 CAM69841.1 - 2.7e-43 147.3 0.1 5.7e-42 143.0 0.0 2.2 2 0 0 2 2 2 1 DEAD_2 ResIII PF04851.10 CAM69841.1 - 7.5e-05 22.6 0.0 0.0026 17.6 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CAM69841.1 - 0.00021 20.8 0.0 0.007 15.8 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_11 PF13086.1 CAM69841.1 - 0.025 14.1 0.0 0.11 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 CAM69841.1 - 0.028 14.1 0.1 0.15 11.8 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain DUF2017 PF09438.5 CAM69841.1 - 0.041 13.4 0.3 0.085 12.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2017) SNF2_N PF00176.18 CAM69841.1 - 0.14 10.9 0.0 0.55 8.9 0.0 1.9 1 1 0 1 1 1 0 SNF2 family N-terminal domain Pkinase PF00069.20 CAM69842.1 - 1.3e-63 214.6 0.0 1.7e-63 214.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM69842.1 - 5.7e-41 140.2 0.0 8.1e-41 139.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM69842.1 - 7.9e-06 25.0 0.0 6e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CAM69842.1 - 0.00021 21.1 0.1 0.19 11.4 0.0 2.9 3 0 0 3 3 3 2 Phosphotransferase enzyme family KdpD PF02702.12 CAM69842.1 - 0.036 13.1 0.1 0.075 12.1 0.1 1.4 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain PDEase_I PF00233.14 CAM69843.1 - 2.2e-36 125.7 0.0 4.8e-36 124.6 0.0 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase FYVE PF01363.16 CAM69843.1 - 1.9e-08 34.0 12.9 4.8e-08 32.7 9.0 1.7 1 0 0 1 1 1 1 FYVE zinc finger XLF PF09302.6 CAM69843.1 - 0.44 10.2 11.8 1.1 9.0 0.0 3.8 4 0 0 4 4 4 0 XLF (XRCC4-like factor) DUF4279 PF14106.1 CAM69843.1 - 4.8 7.0 6.0 33 4.3 0.1 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4279) Beta_helix PF13229.1 CAM69846.1 - 6.4e-18 65.0 0.3 4.6e-17 62.2 0.2 2.1 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.8 CAM69846.1 - 2.9e-12 46.2 0.0 4e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Pectate_lyase_3 PF12708.2 CAM69846.1 - 0.0061 16.7 0.2 0.039 14.0 0.1 2.2 1 1 0 1 1 1 1 Pectate lyase superfamily protein Pkinase PF00069.20 CAM69847.1 - 2.8e-34 118.4 0.0 3.2e-32 111.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM69847.1 - 9e-17 60.9 0.0 1.3e-16 60.4 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CAM69847.1 - 0.0014 17.6 0.0 0.003 16.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CAM69847.1 - 0.044 13.1 0.0 0.098 11.9 0.0 1.5 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Ribosomal_S19e PF01090.14 CAM69850.1 - 2.6e-45 153.2 0.0 3e-45 153.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Mrr_N PF14338.1 CAM69850.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Mrr N-terminal domain RRM_1 PF00076.17 CAM69853.1 - 1.7e-18 65.9 0.0 2.5e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM69853.1 - 3.5e-12 46.1 0.0 5.7e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM69853.1 - 7.7e-10 38.4 0.0 1.2e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LRR_6 PF13516.1 CAM69855.1 - 1.3e-27 92.7 27.9 0.011 15.6 0.5 13.5 14 0 0 14 14 14 8 Leucine Rich repeat LRR_1 PF00560.28 CAM69855.1 - 1.3e-13 48.9 9.2 2.1 8.6 0.1 10.7 10 1 1 11 11 11 3 Leucine Rich Repeat LRR_4 PF12799.2 CAM69855.1 - 1.9e-12 46.5 10.1 0.071 12.7 0.0 7.2 5 2 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM69855.1 - 8.7e-06 25.4 19.5 0.024 14.3 1.6 6.7 5 2 2 7 7 7 2 Leucine rich repeat SPX PF03105.14 CAM69855.1 - 0.038 13.7 0.6 0.048 13.4 0.4 1.3 1 0 0 1 1 1 0 SPX domain LRR_7 PF13504.1 CAM69855.1 - 0.11 12.7 26.6 24 5.6 0.4 9.9 11 0 0 11 11 11 0 Leucine rich repeat AAA_13 PF13166.1 CAM69855.1 - 0.33 9.3 10.4 0.45 8.9 7.2 1.1 1 0 0 1 1 1 0 AAA domain DUF1664 PF07889.7 CAM69855.1 - 1.1 9.0 8.4 3.2 7.5 2.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Occludin_ELL PF07303.8 CAM69855.1 - 1.2 9.8 5.6 0.47 11.2 1.7 2.0 2 0 0 2 2 2 0 Occludin homology domain DUF4337 PF14235.1 CAM69855.1 - 1.6 8.5 9.1 4.2 7.1 2.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Acyl_transf_3 PF01757.17 CAM69856.1 - 0.048 12.4 1.5 0.056 12.2 1.0 1.1 1 0 0 1 1 1 0 Acyltransferase family Tim17 PF02466.14 CAM69856.1 - 0.12 12.4 5.0 0.11 12.5 2.3 1.7 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family DUF3815 PF12821.2 CAM69856.1 - 0.24 11.3 3.6 0.41 10.5 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3815) DUF4131 PF13567.1 CAM69856.1 - 2.9 7.2 8.5 1.1 8.5 0.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) IU_nuc_hydro PF01156.14 CAM69857.1 - 3.1e-48 164.6 0.0 3.6e-48 164.3 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase START PF01852.14 CAM69858.1 - 2e-24 86.0 0.0 4e-24 85.0 0.0 1.4 2 0 0 2 2 2 1 START domain Actin PF00022.14 CAM69859.1 - 9.7e-19 67.0 0.0 6.7e-13 47.8 0.0 2.1 1 1 0 2 2 2 2 Actin DUF2367 PF10164.4 CAM69860.1 - 0.12 12.2 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) ATP-synt_DE PF00401.15 CAM69860.1 - 0.3 11.0 3.7 0.46 10.3 2.6 1.3 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain TPR_19 PF14559.1 CAM69861.1 - 1.4e-13 50.9 2.3 0.0031 17.8 0.1 5.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 CAM69861.1 - 1.6e-10 41.3 2.1 0.011 16.3 0.0 4.4 4 1 1 5 5 4 4 Tetratricopeptide repeat Apc3 PF12895.2 CAM69861.1 - 1.9e-09 37.4 15.0 0.06 13.4 0.5 5.0 2 2 3 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 CAM69861.1 - 6.4e-08 31.9 20.5 0.045 13.6 0.0 6.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.1 CAM69861.1 - 1.1e-06 28.1 1.3 1.1e-06 28.1 0.9 4.3 3 1 1 4 4 4 2 TPR repeat TPR_14 PF13428.1 CAM69861.1 - 5.8e-05 23.3 6.3 0.86 10.4 0.1 5.2 6 1 1 7 7 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 CAM69861.1 - 0.00075 18.9 16.6 0.11 12.1 0.2 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 CAM69861.1 - 0.0042 17.4 10.6 8.6 7.0 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 CAM69861.1 - 0.042 13.6 4.6 1 9.3 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 CAM69861.1 - 0.087 12.7 13.9 3.4 7.6 0.0 5.3 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 CAM69861.1 - 0.13 12.4 2.3 4.3 7.7 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 CAM69861.1 - 1.5 8.8 14.9 7.6 6.5 0.1 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat Trypsin_2 PF13365.1 CAM69862.1 - 0.025 14.5 0.9 0.083 12.8 0.6 1.8 1 1 0 1 1 1 0 Trypsin-like peptidase domain Peptidase_C4 PF00863.14 CAM69862.1 - 0.072 12.0 0.0 0.089 11.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C4 Peptidase_S29 PF02907.10 CAM69862.1 - 0.073 12.5 0.2 0.12 11.8 0.2 1.4 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease Mito_carr PF00153.22 CAM69863.1 - 2.6e-60 200.1 1.1 1.9e-20 72.3 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Abhydrolase_6 PF12697.2 CAM69864.1 - 1.9e-17 63.8 0.9 2.8e-17 63.3 0.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CAM69864.1 - 3.3e-08 33.3 0.0 7.5e-08 32.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAM69864.1 - 1.6e-06 27.8 0.0 4.2e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Pro_isomerase PF00160.16 CAM69865.1 - 1.7e-19 70.5 0.0 2.9e-19 69.8 0.0 1.4 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD UPF0220 PF05255.6 CAM69867.1 - 1.9e-17 62.9 0.8 3.6e-17 62.0 0.6 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0220) BacA PF02673.13 CAM69867.1 - 0.0055 15.9 0.2 0.0086 15.3 0.1 1.4 1 1 0 1 1 1 1 Bacitracin resistance protein BacA SLAC1 PF03595.12 CAM69867.1 - 0.017 13.7 3.1 0.025 13.2 2.1 1.3 1 0 0 1 1 1 0 Voltage-dependent anion channel Adeno_E3_CR2 PF02439.10 CAM69867.1 - 0.24 10.9 1.0 3.1 7.4 0.2 2.6 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Yip1 PF04893.12 CAM69867.1 - 1.9 7.9 7.1 6.3 6.2 4.9 1.8 1 1 0 1 1 1 0 Yip1 domain MATH PF00917.21 CAM69868.1 - 2.3e-06 27.8 0.1 7.5e-06 26.1 0.1 2.0 1 0 0 1 1 1 1 MATH domain CorA PF01544.13 CAM69868.1 - 5.7 5.8 14.0 11 4.8 9.2 1.9 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Mnd1 PF03962.10 CAM69868.1 - 5.8 6.5 48.4 0.046 13.3 18.2 3.6 2 1 1 3 3 3 0 Mnd1 family DCP1 PF06058.8 CAM69869.1 - 0.14 12.2 0.0 24 4.9 0.0 2.3 2 0 0 2 2 2 0 Dcp1-like decapping family Phycoerythr_ab PF02972.9 CAM69870.1 - 0.15 11.6 0.2 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Phycoerythrin, alpha/beta chain Cyclin_N PF00134.18 CAM69871.1 - 7.1e-24 83.7 0.1 1.6e-23 82.6 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain LRR_8 PF13855.1 CAM69874.1 - 9.9e-08 31.6 4.2 0.0018 17.9 0.3 4.1 4 0 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.2 CAM69874.1 - 1.3e-06 27.8 6.9 0.00011 21.7 0.4 4.6 4 2 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CAM69874.1 - 0.00042 19.9 6.2 5.9 7.3 0.0 6.1 7 1 0 7 7 7 2 Leucine Rich Repeat LRR_6 PF13516.1 CAM69874.1 - 0.011 15.6 5.1 19 5.6 0.0 5.8 6 0 0 6 6 6 0 Leucine Rich repeat LRR_7 PF13504.1 CAM69874.1 - 1.9 9.0 11.0 9.3 6.9 0.0 5.5 5 1 1 6 6 6 0 Leucine rich repeat FAD-oxidase_C PF02913.14 CAM69875.1 - 6.5e-48 163.2 0.0 1.2e-47 162.3 0.0 1.5 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CAM69875.1 - 3e-38 130.4 0.0 5e-38 129.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 CAM69875.1 - 0.02 14.7 0.0 0.063 13.1 0.0 1.8 1 0 0 1 1 1 0 Berberine and berberine like tRNA-synt_2 PF00152.15 CAM69876.1 - 3.9e-87 292.1 0.0 4.8e-87 291.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 CAM69876.1 - 8.9e-10 38.1 0.1 0.00015 21.0 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 CAM69876.1 - 7.1e-07 29.0 0.0 1.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 CAM69876.1 - 0.019 14.5 0.0 0.93 9.0 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) Yip1 PF04893.12 CAM69877.1 - 6.2e-10 38.8 17.1 1.3e-09 37.7 11.8 1.5 1 1 0 1 1 1 1 Yip1 domain Cnd1_N PF12922.2 CAM69877.1 - 0.18 11.4 0.1 0.32 10.6 0.1 1.3 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term LRR_6 PF13516.1 CAM69878.1 - 2.3e-21 73.4 0.1 2.5e-06 26.9 0.0 5.2 5 0 0 5 5 5 4 Leucine Rich repeat LRR_4 PF12799.2 CAM69878.1 - 2.3e-10 39.8 0.5 3.3e-05 23.4 0.0 3.3 2 2 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CAM69878.1 - 1.8e-06 27.1 0.0 0.19 11.8 0.0 5.0 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_8 PF13855.1 CAM69878.1 - 0.00018 21.1 1.7 0.0055 16.4 0.7 3.1 1 1 1 2 2 2 1 Leucine rich repeat LRR_7 PF13504.1 CAM69878.1 - 0.00028 20.5 4.0 0.14 12.4 0.0 4.8 5 0 0 5 5 5 1 Leucine rich repeat Lgl_C PF08596.5 CAM69878.1 - 0.0077 14.7 0.1 0.92 7.9 0.0 2.1 2 0 0 2 2 2 2 Lethal giant larvae(Lgl) like, C-terminal Rubis-subs-bind PF09273.6 CAM69879.1 - 5.4e-11 42.4 0.0 1.9e-10 40.7 0.0 1.9 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding NAD_binding_2 PF03446.10 CAM69880.1 - 8.1e-52 175.3 0.5 1.3e-51 174.6 0.3 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 CAM69880.1 - 1.8e-34 118.4 0.3 3.1e-34 117.6 0.2 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.14 CAM69880.1 - 9.9e-06 24.8 0.3 3.9e-05 22.8 0.0 2.1 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 CAM69880.1 - 0.00042 20.6 1.7 0.00077 19.8 0.0 2.4 4 0 0 4 4 4 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 CAM69880.1 - 0.00098 18.8 0.2 0.0023 17.6 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 CAM69880.1 - 0.0019 18.2 0.0 0.0036 17.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.9 CAM69880.1 - 0.0021 17.4 0.0 0.16 11.3 0.0 2.5 1 1 1 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IlvN PF07991.7 CAM69880.1 - 0.016 14.5 0.0 0.033 13.5 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain MAGE_N PF12440.3 CAM69881.1 - 0.072 13.3 0.5 0.072 13.3 0.4 2.2 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal Gly-zipper_OmpA PF13436.1 CAM69882.1 - 0.0006 19.4 3.2 0.00085 18.9 2.2 1.1 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_Omp PF13488.1 CAM69882.1 - 0.059 13.0 6.8 0.095 12.3 4.7 1.3 1 0 0 1 1 1 0 Glycine zipper Rick_17kDa_Anti PF05433.10 CAM69882.1 - 2.7 7.7 9.2 6.2 6.5 6.4 1.6 1 1 0 1 1 1 0 Glycine zipper 2TM domain Bacteriocin_IIc PF10439.4 CAM69882.1 - 3.3 7.9 10.6 5.2 7.2 7.3 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide RrnaAD PF00398.15 CAM69883.1 - 1.3e-58 198.0 0.0 1.8e-58 197.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 CAM69883.1 - 7.8e-09 35.5 0.0 1.7e-08 34.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAM69883.1 - 6.7e-06 25.7 0.0 9.4e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAM69883.1 - 7.9e-06 26.4 0.0 1.4e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CAM69883.1 - 0.00012 22.5 0.0 0.00022 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAM69883.1 - 0.00015 21.5 0.0 0.00025 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CAM69883.1 - 0.00043 19.7 0.0 0.0008 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 CAM69883.1 - 0.0021 18.5 0.0 0.0043 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CAM69883.1 - 0.0068 15.4 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.14 CAM69883.1 - 0.0094 15.5 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 CAM69883.1 - 0.024 14.9 0.0 0.042 14.2 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 CAM69883.1 - 0.056 12.3 0.0 0.094 11.5 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_28 PF02636.12 CAM69883.1 - 0.066 12.6 0.0 0.095 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.13 CAM69883.1 - 0.099 11.7 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family LELP1 PF15042.1 CAM69883.1 - 0.15 12.2 0.5 5.8 7.1 0.2 2.2 2 0 0 2 2 2 0 Late cornified envelope-like proline-rich protein 1 zf-RanBP PF00641.13 CAM69884.1 - 0.0041 16.1 1.6 0.0041 16.1 1.1 1.7 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others VHS PF00790.14 CAM69884.1 - 0.067 12.8 0.0 0.099 12.2 0.0 1.2 1 0 0 1 1 1 0 VHS domain Mito_carr PF00153.22 CAM69885.1 - 2.9e-14 52.5 0.1 1.3e-10 40.8 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial carrier protein Tim17 PF02466.14 CAM69885.1 - 0.00073 19.5 0.3 0.0034 17.4 0.1 2.1 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family RNase_T PF00929.19 CAM69887.1 - 3.7e-22 79.3 0.0 7.8e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 Exonuclease UCH_1 PF13423.1 CAM69887.1 - 4.2e-21 75.6 0.0 5e-20 72.1 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C2H2 PF00096.21 CAM69888.1 - 5.8e-12 45.2 46.3 0.055 13.8 0.7 8.3 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CAM69888.1 - 2.5e-08 33.6 47.3 0.15 12.4 0.3 8.3 8 0 0 8 8 8 5 C2H2-type zinc finger zf-Di19 PF05605.7 CAM69888.1 - 3.3e-08 33.5 32.5 0.00077 19.5 1.8 7.1 7 0 0 7 7 7 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 CAM69888.1 - 6.2e-07 29.3 9.4 0.073 13.2 0.1 5.1 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CAM69888.1 - 1.8e-06 27.9 16.2 0.0065 16.6 0.4 5.8 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-met2 PF12907.2 CAM69888.1 - 3.3e-05 23.7 14.6 0.056 13.4 0.3 5.7 6 0 0 6 6 6 2 Zinc-binding DUF629 PF04780.7 CAM69888.1 - 0.00042 18.9 4.9 3.4 6.0 0.0 5.1 5 0 0 5 5 5 1 Protein of unknown function (DUF629) zf-C2H2_6 PF13912.1 CAM69888.1 - 0.02 14.8 22.4 3.1 7.8 0.1 6.6 7 0 0 7 7 7 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 CAM69888.1 - 0.053 13.1 11.6 2.1 8.0 0.1 4.0 3 0 0 3 3 3 0 zinc-finger of a C2HC-type RNA_POL_M_15KD PF02150.11 CAM69888.1 - 0.085 12.5 0.3 0.085 12.5 0.2 2.3 2 0 0 2 2 1 0 RNA polymerases M/15 Kd subunit zf-H2C2_5 PF13909.1 CAM69888.1 - 0.25 11.6 0.0 0.25 11.6 0.0 5.8 5 0 0 5 5 5 0 C2H2-type zinc-finger domain LIM PF00412.17 CAM69888.1 - 0.39 10.8 6.7 0.85 9.7 0.1 3.8 3 1 0 3 3 3 0 LIM domain zf-C2H2_2 PF12756.2 CAM69888.1 - 0.94 9.6 21.8 4.8 7.3 0.3 6.4 5 2 2 7 7 7 0 C2H2 type zinc-finger (2 copies) Baculo_ME53 PF06061.6 CAM69888.1 - 1.8 7.4 6.1 3 6.7 0.2 2.5 2 0 0 2 2 2 0 Baculoviridae ME53 zf-CSL PF05207.8 CAM69888.1 - 8.1 6.0 11.1 59 3.2 3.5 3.8 2 1 0 2 2 2 0 CSL zinc finger Peptidase_C54 PF03416.14 CAM69889.1 - 5.1e-38 130.8 0.1 5.2e-37 127.4 0.0 1.9 1 1 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.8 CAM69889.1 - 0.023 13.7 0.0 0.079 12.0 0.0 1.8 2 0 0 2 2 2 0 Peptidase family C78 LIM PF00412.17 CAM69890.1 - 2.4e-05 24.2 11.2 3e-05 23.9 5.9 2.3 2 1 0 2 2 2 1 LIM domain zf-PARP PF00645.13 CAM69890.1 - 0.031 14.5 1.4 0.61 10.3 0.4 2.6 2 1 0 2 2 2 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region WHIM2 PF15613.1 CAM69890.1 - 0.15 12.0 0.5 0.48 10.4 0.0 2.1 2 0 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 2 NCD3G PF07562.9 CAM69890.1 - 0.23 11.2 7.1 3.5 7.4 1.7 2.4 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR XhlA PF10779.4 CAM69893.1 - 0.14 12.1 0.1 0.14 12.1 0.0 3.9 4 0 0 4 4 4 0 Haemolysin XhlA Sad1_UNC PF07738.8 CAM69894.1 - 4.9e-21 74.9 0.0 7.4e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal RabGAP-TBC PF00566.13 CAM69928.2 - 1.3e-07 31.2 0.5 2.1e-07 30.6 0.4 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rhodanese PF00581.15 CAM69928.2 - 0.0055 17.0 0.0 0.014 15.7 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Ku PF02735.11 CAM69929.1 - 3.5e-16 59.2 0.0 7.1e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.6 CAM69929.1 - 1.2e-14 54.2 0.0 3e-14 52.9 0.0 1.8 2 0 0 2 2 2 1 Ku C terminal domain like Ku_N PF03731.10 CAM69929.1 - 7.9e-11 41.8 0.0 1.5e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Kinesin PF00225.18 CAM69930.1 - 1.4e-88 296.8 1.4 2.1e-88 296.2 1.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF904 PF06005.7 CAM69930.1 - 0.0044 17.2 1.0 1.9 8.8 2.3 3.0 2 2 0 2 2 2 1 Protein of unknown function (DUF904) TMF_DNA_bd PF12329.3 CAM69930.1 - 0.0047 16.6 8.7 0.08 12.7 0.2 3.2 3 0 0 3 3 3 2 TATA element modulatory factor 1 DNA binding AAA_22 PF13401.1 CAM69930.1 - 0.015 15.4 0.2 0.31 11.1 0.0 3.0 2 1 1 3 3 3 0 AAA domain PIF1 PF05970.9 CAM69930.1 - 0.026 13.4 0.2 0.069 12.0 0.1 1.6 1 0 0 1 1 1 0 PIF1-like helicase AAA_16 PF13191.1 CAM69930.1 - 0.048 13.6 0.0 0.34 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain DUF972 PF06156.8 CAM69930.1 - 0.32 11.3 5.3 0.14 12.5 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF972) EMP70 PF02990.11 CAM69931.1 - 4.7e-132 441.1 7.5 7.2e-132 440.4 5.2 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Pkinase PF00069.20 CAM69932.1 - 2.1e-59 200.7 0.0 3.2e-59 200.1 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM69932.1 - 2e-26 92.6 0.0 3.1e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM69932.1 - 1.3e-05 24.2 0.0 0.00044 19.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like DUF3455 PF11937.3 CAM69932.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3455) Seadorna_VP7 PF07387.6 CAM69932.1 - 0.17 10.7 0.0 0.28 9.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 PP2C PF00481.16 CAM69933.1 - 1.9e-48 165.0 0.1 2.6e-48 164.6 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CAM69933.1 - 2.4e-06 27.0 0.1 1.7e-05 24.3 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 CAM69933.1 - 1.4e-05 24.8 0.0 5.1e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Shisa PF13908.1 CAM69934.1 - 3e-06 27.5 1.8 3.4e-06 27.3 0.5 1.5 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator DUF2946 PF11162.3 CAM69934.1 - 0.041 14.0 0.9 0.041 14.0 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2946) Pex14_N PF04695.8 CAM69934.1 - 0.78 9.7 7.1 3.6 7.6 0.0 2.4 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Abhydrolase_5 PF12695.2 CAM69935.1 - 2.6e-14 53.1 0.0 6.5e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CAM69935.1 - 2.6e-12 47.1 0.5 6.4e-12 45.8 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 CAM69935.1 - 5.1e-08 32.6 0.0 2.8e-07 30.2 0.0 1.9 1 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.15 CAM69935.1 - 8.2e-06 25.5 0.2 0.035 13.6 0.1 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CAM69935.1 - 0.00062 19.0 0.0 0.0097 15.1 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 CAM69935.1 - 0.0066 16.2 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Esterase PF00756.15 CAM69935.1 - 0.013 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Putative esterase PhoPQ_related PF10142.4 CAM69935.1 - 0.15 10.4 0.0 0.2 10.1 0.0 1.1 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein BAAT_C PF08840.6 CAM69935.1 - 0.17 11.5 0.0 0.33 10.6 0.0 1.4 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.7 CAM69935.1 - 0.23 9.9 0.0 17 3.8 0.0 2.2 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) PAP2 PF01569.16 CAM69936.1 - 3.1e-21 75.3 4.5 5.4e-21 74.6 3.1 1.4 1 0 0 1 1 1 1 PAP2 superfamily Scs3p PF10261.4 CAM69936.1 - 0.019 14.0 0.5 0.045 12.7 0.0 1.8 2 1 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM ODAM PF15424.1 CAM69936.1 - 0.029 13.8 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 Odontogenic ameloblast-associated family TM2 PF05154.11 CAM69936.1 - 7.6 6.8 13.7 2.6 8.3 6.5 2.4 2 1 0 2 2 2 0 TM2 domain WD40 PF00400.27 CAM69937.1 - 8.5e-44 145.9 12.3 1.4e-12 46.9 0.3 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 CAM69937.1 - 1.4e-06 28.1 0.0 0.16 11.6 0.0 3.1 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 CAM69937.1 - 0.14 11.6 0.0 10 5.7 0.0 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DAGK_cat PF00781.19 CAM69938.1 - 2.4e-11 43.1 0.1 4.3e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Evr1_Alr PF04777.8 CAM69939.1 - 1.5e-10 40.7 0.0 5.8e-10 38.9 0.0 2.1 2 0 0 2 2 2 1 Erv1 / Alr family Thioredoxin PF00085.15 CAM69939.1 - 8.5e-08 31.8 0.0 2.1e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin RRF PF01765.14 CAM69940.1 - 1.2e-14 54.1 1.8 1.2e-14 54.1 1.2 1.6 1 1 1 2 2 2 1 Ribosome recycling factor Activator-TraM PF11657.3 CAM69940.1 - 0.063 12.7 4.6 0.095 12.1 0.4 2.3 2 0 0 2 2 2 0 Transcriptional activator TraM Nab2 PF11517.3 CAM69940.1 - 0.08 13.0 1.1 0.32 11.0 0.1 2.5 2 1 0 3 3 3 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Peptidase_S49 PF01343.13 CAM69940.1 - 0.18 11.5 4.5 4 7.1 0.1 2.9 2 1 1 3 3 3 0 Peptidase family S49 DUF3181 PF11378.3 CAM69940.1 - 0.45 10.5 2.3 9.7 6.2 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3181) CBFD_NFYB_HMF PF00808.18 CAM69940.1 - 1 9.4 3.6 0.56 10.2 0.5 2.1 2 1 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone IF4E PF01652.13 CAM69941.1 - 9.2e-32 109.8 0.0 1.3e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E tRNA-synt_2 PF00152.15 CAM69942.1 - 5.8e-73 245.5 0.0 8.5e-73 245.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CAM69942.1 - 1.5e-09 37.5 0.1 2.7e-09 36.7 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CAM69942.1 - 3.4e-05 23.1 0.2 0.13 11.4 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Retinal PF15449.1 CAM69943.1 - 2 5.9 9.5 2.8 5.4 6.6 1.1 1 0 0 1 1 1 0 Retinal protein Bystin PF05291.6 CAM69944.1 - 2.9e-109 364.6 0.2 4.5e-109 364.0 0.1 1.1 1 0 0 1 1 1 1 Bystin GMC_oxred_C PF05199.8 CAM69944.1 - 0.025 14.8 0.1 0.1 12.9 0.0 2.0 2 0 0 2 2 2 0 GMC oxidoreductase Nucleoplasmin PF03066.10 CAM69946.1 - 0.0086 15.5 7.2 0.014 14.9 5.0 1.2 1 0 0 1 1 1 1 Nucleoplasmin PBP1_TM PF14812.1 CAM69946.1 - 0.061 13.6 6.0 0.23 11.8 4.2 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.7 CAM69946.1 - 0.065 11.1 4.3 0.11 10.4 3.0 1.3 1 0 0 1 1 1 0 Nop14-like family DUF4611 PF15387.1 CAM69946.1 - 0.26 11.4 8.0 0.046 13.8 2.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) CDC45 PF02724.9 CAM69946.1 - 1 7.3 4.4 1.6 6.6 3.0 1.2 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.11 CAM69946.1 - 1.3 7.9 4.1 2.1 7.2 2.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RXT2_N PF08595.6 CAM69946.1 - 2.6 7.8 6.7 5.2 6.8 3.5 2.0 2 0 0 2 2 2 0 RXT2-like, N-terminal NOA36 PF06524.7 CAM69946.1 - 2.9 7.0 5.6 4.3 6.5 3.9 1.2 1 0 0 1 1 1 0 NOA36 protein Pox_RNA_Pol_19 PF05320.7 CAM69946.1 - 5.9 6.6 8.8 2 8.1 4.2 1.5 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit TLP-20 PF06088.6 CAM69946.1 - 6.2 6.4 6.2 11 5.6 4.3 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) LRR_4 PF12799.2 CAM69947.1 - 1.4e-09 37.3 0.1 3.3e-05 23.3 0.0 3.3 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM69947.1 - 0.00016 21.3 0.1 0.00086 19.0 0.0 2.3 2 0 0 2 2 2 1 Leucine rich repeat LRR_6 PF13516.1 CAM69947.1 - 0.04 13.9 0.1 3.1 8.1 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.28 CAM69947.1 - 0.11 12.6 0.7 34 5.0 0.0 4.1 4 0 0 4 4 4 0 Leucine Rich Repeat NatB_MDM20 PF09797.4 CAM69948.2 - 1.4e-76 257.6 0.0 3e-76 256.5 0.0 1.5 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_14 PF13428.1 CAM69948.2 - 0.014 15.9 15.2 0.1 13.3 0.6 5.6 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 CAM69948.2 - 1.1 9.5 15.0 0.73 10.2 0.6 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Alg14 PF08660.6 CAM69949.1 - 1.2e-54 184.8 0.0 1.9e-54 184.2 0.0 1.3 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Glyco_tran_28_C PF04101.11 CAM69949.1 - 1.2e-19 70.5 0.0 3.5e-19 69.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 CAM69949.1 - 0.013 14.7 0.1 0.047 12.8 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 1 RRM_1 PF00076.17 CAM69950.1 - 6.1e-15 54.6 0.0 9.6e-15 53.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM69950.1 - 3.4e-12 46.1 0.0 5.6e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM69950.1 - 6.1e-09 35.6 0.0 8.5e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phospho_p8 PF10195.4 CAM69950.1 - 0.07 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 DNA-binding nuclear phosphoprotein p8 LMBR1 PF04791.11 CAM69951.1 - 1.9e-25 89.3 26.9 5.6e-25 87.8 18.6 1.7 1 1 0 1 1 1 1 LMBR1-like membrane protein DIT1_PvcA PF05141.7 CAM69952.1 - 9.6 5.4 8.7 2.5 7.3 0.0 2.6 3 0 0 3 3 3 0 Pyoverdine/dityrosine biosynthesis protein PSP PF04046.11 CAM69953.1 - 3.1e-20 71.2 4.7 8.6e-20 69.8 3.2 1.8 1 0 0 1 1 1 1 PSP DUF382 PF04037.8 CAM69953.1 - 1.6e-12 47.3 0.1 3.4e-11 43.0 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF382) LUC7 PF03194.10 CAM69953.1 - 1.6 8.1 4.4 2.1 7.7 3.1 1.2 1 0 0 1 1 1 0 LUC7 N_terminus AMP-binding PF00501.23 CAM69954.1 - 9.6e-27 93.4 0.0 2.8e-12 45.7 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme BBS2_C PF14782.1 CAM69955.1 - 1.1e-132 442.6 0.0 1.5e-132 442.1 0.0 1.2 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_N PF14781.1 CAM69955.1 - 2.1e-32 111.5 0.0 5e-32 110.3 0.0 1.6 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, N-terminal BBS2_Mid PF14783.1 CAM69955.1 - 2.5e-28 98.0 0.0 1.7e-27 95.3 0.0 2.5 3 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region FG-GAP PF01839.18 CAM69955.1 - 8.2e-05 22.1 0.5 0.00028 20.4 0.3 1.9 1 0 0 1 1 1 1 FG-GAP repeat VCBS PF13517.1 CAM69955.1 - 0.0034 17.7 0.4 0.013 15.8 0.1 2.3 2 0 0 2 2 2 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FlgN PF05130.7 CAM69955.1 - 0.0088 16.2 2.2 0.0088 16.2 1.5 2.3 2 1 0 2 2 2 1 FlgN protein HALZ PF02183.13 CAM69955.1 - 0.18 11.5 2.5 0.56 9.9 1.8 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper Pkinase PF00069.20 CAM69956.1 - 1.3e-64 217.9 0.0 1.7e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM69956.1 - 7.7e-41 139.8 0.0 1.1e-40 139.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM69956.1 - 0.00032 19.7 0.0 0.0031 16.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Cyt-b5 PF00173.23 CAM69957.1 - 4.8e-28 96.7 0.0 1.3e-17 63.3 0.0 2.3 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.19 CAM69957.1 - 2.2e-10 40.5 0.0 4.9e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 CAM69957.1 - 8.4e-10 39.1 0.0 2.2e-09 37.8 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 CAM69957.1 - 5.3e-07 29.6 0.0 0.0002 21.3 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain RRS1 PF04939.7 CAM69958.1 - 6.4e-47 159.0 5.3 6.4e-47 159.0 3.7 1.4 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) DUF106 PF01956.11 CAM69958.1 - 2.1 7.8 5.5 4 6.9 3.8 1.4 1 0 0 1 1 1 0 Integral membrane protein DUF106 FliD_N PF02465.13 CAM69958.1 - 3.5 8.0 7.7 1.6 9.1 3.6 1.6 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus tRNA-synt_His PF13393.1 CAM69959.1 - 4.7e-40 137.5 0.0 6.9e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 CAM69959.1 - 1.8e-15 56.9 0.0 2.8e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CAM69959.1 - 4.1e-06 26.6 0.7 1.3e-05 24.9 0.1 2.1 2 1 0 2 2 2 1 Anticodon binding domain PPR_3 PF13812.1 CAM69961.1 - 0.087 13.1 0.0 0.34 11.3 0.0 2.0 1 0 0 1 1 1 0 Pentatricopeptide repeat domain PDZ_2 PF13180.1 CAM69962.1 - 1e-11 44.5 0.0 4.5e-11 42.4 0.0 2.1 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.19 CAM69962.1 - 6.1e-07 29.5 0.1 2.5e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) PI-PLC-X PF00388.14 CAM69962.1 - 2.1e-05 23.9 0.0 4.1e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain EF-hand_like PF09279.6 CAM69962.1 - 7e-05 22.7 0.1 0.00024 21.0 0.0 1.9 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like Ribosomal_S30 PF04758.9 CAM69963.1 - 5e-28 96.6 6.7 5.7e-28 96.4 4.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Ribosomal_S30 PF04758.9 CAM69964.1 - 5e-28 96.6 6.7 5.7e-28 96.4 4.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Ribosomal_S30 PF04758.9 CAM69965.1 - 5e-28 96.6 6.7 5.7e-28 96.4 4.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 CS PF04969.11 CAM69966.1 - 1.2e-16 61.0 0.0 2e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 CAM69968.1 - 8.6e-27 92.5 17.8 9.3e-11 41.2 0.8 6.1 5 1 1 6 6 6 4 TPR repeat TPR_2 PF07719.12 CAM69968.1 - 1.2e-25 87.2 19.7 0.00047 19.8 0.3 9.0 10 0 0 10 10 8 6 Tetratricopeptide repeat TPR_1 PF00515.23 CAM69968.1 - 4.3e-24 83.0 14.7 3.3e-05 23.3 0.2 7.8 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.1 CAM69968.1 - 1.8e-18 66.6 9.7 0.0014 19.2 0.0 6.5 5 1 1 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 CAM69968.1 - 1.5e-17 63.3 14.9 4.8e-08 32.8 0.5 5.4 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 CAM69968.1 - 1.6e-17 63.5 1.0 0.00027 21.2 0.1 6.3 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 CAM69968.1 - 2.3e-16 58.1 8.4 0.00027 20.5 0.1 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 CAM69968.1 - 1e-12 46.8 13.3 0.004 16.8 0.3 6.4 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 CAM69968.1 - 9.2e-12 44.4 10.5 0.29 11.8 0.0 8.1 7 2 3 10 10 8 4 Tetratricopeptide repeat Apc3 PF12895.2 CAM69968.1 - 2.5e-09 37.1 24.6 0.0022 18.0 1.1 4.5 4 2 1 5 5 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 CAM69968.1 - 1.5e-08 34.0 0.7 0.00063 18.8 0.0 4.1 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 CAM69968.1 - 1.1e-07 31.8 13.6 0.0026 18.1 0.5 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 CAM69968.1 - 0.00033 20.4 5.5 0.4 10.5 0.0 4.9 4 1 0 4 4 4 1 Tetratricopeptide repeat SNAP PF14938.1 CAM69968.1 - 0.0027 16.9 2.5 0.0027 16.9 1.7 2.8 2 1 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_17 PF13431.1 CAM69968.1 - 0.0046 17.0 12.0 15 6.0 0.0 7.3 10 1 1 11 11 7 0 Tetratricopeptide repeat TPR_4 PF07721.9 CAM69968.1 - 0.012 15.9 0.5 48 4.7 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat BTAD PF03704.12 CAM69968.1 - 0.032 14.5 9.9 0.75 10.0 0.0 4.6 4 2 2 6 6 5 0 Bacterial transcriptional activator domain TPR_10 PF13374.1 CAM69968.1 - 0.053 13.4 16.7 0.059 13.3 0.2 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat NARP1 PF12569.3 CAM69968.1 - 0.075 11.7 0.2 0.26 9.9 0.0 1.7 2 1 0 2 2 2 0 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.1 CAM69968.1 - 0.15 11.9 16.1 2.6 7.9 0.1 6.1 7 0 0 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat Sel1 PF08238.7 CAM69968.1 - 0.18 12.5 16.0 12 6.6 0.0 6.0 7 0 0 7 7 6 0 Sel1 repeat DUF3856 PF12968.2 CAM69968.1 - 0.21 11.3 2.8 0.36 10.6 0.2 2.6 3 0 0 3 3 2 0 Domain of Unknown Function (DUF3856) TPR_3 PF07720.7 CAM69968.1 - 0.69 9.7 7.7 5.3 6.9 0.0 5.1 7 0 0 7 7 5 0 Tetratricopeptide repeat GrpE PF01025.14 CAM69970.1 - 1.7e-41 141.5 3.7 2.1e-41 141.2 2.5 1.2 1 0 0 1 1 1 1 GrpE Met_gamma_lyase PF06838.6 CAM69970.1 - 0.1 10.8 0.0 0.13 10.5 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase GrpE PF01025.14 CAM69971.1 - 3.7e-33 114.3 1.3 4.6e-33 114.1 0.9 1.0 1 0 0 1 1 1 1 GrpE MTBP_C PF14920.1 CAM69971.1 - 0.0029 17.1 1.4 0.0038 16.7 0.9 1.1 1 0 0 1 1 1 1 MDM2-binding BALF1 PF06861.6 CAM69971.1 - 0.03 13.7 0.1 0.043 13.2 0.1 1.2 1 0 0 1 1 1 0 BALF1 protein ZapA PF05164.8 CAM69971.1 - 0.031 14.2 1.2 0.089 12.7 0.1 2.1 2 0 0 2 2 2 0 Cell division protein ZapA Spore_III_AB PF09548.5 CAM69971.1 - 0.034 13.9 0.2 0.053 13.2 0.1 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Peptidase_S64 PF08192.6 CAM69973.1 - 0.044 12.1 0.2 0.056 11.7 0.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 DJ-1_PfpI PF01965.19 CAM69974.1 - 1.6e-22 79.5 0.1 2.2e-22 79.1 0.1 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 CAM69974.1 - 1.4e-12 47.1 0.0 1.8e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase ThiW PF09512.5 CAM69974.1 - 0.051 13.4 1.6 4.5 7.0 1.1 2.2 1 1 0 1 1 1 0 Thiamine-precursor transporter protein (ThiW) Arm PF00514.18 CAM69975.1 - 2.2e-22 78.0 20.7 0.016 15.0 0.0 11.9 13 0 0 13 13 13 6 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.4 CAM69975.1 - 1.3e-13 50.5 11.5 0.1 12.3 0.0 7.9 5 3 2 8 8 8 6 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.1 CAM69975.1 - 3.2e-09 36.9 11.2 0.0043 17.3 0.3 6.1 6 1 1 7 7 7 3 HEAT repeats HEAT_EZ PF13513.1 CAM69975.1 - 2.8e-05 24.4 11.1 0.42 11.1 0.2 5.9 5 2 0 5 5 5 2 HEAT-like repeat Ric8 PF10165.4 CAM69975.1 - 0.0031 16.3 8.5 0.18 10.6 0.6 4.4 2 1 1 3 3 3 2 Guanine nucleotide exchange factor synembryn DOG1 PF14144.1 CAM69975.1 - 0.053 13.5 2.0 11 6.0 0.0 4.0 4 0 0 4 4 4 0 Seed dormancy control HEAT PF02985.17 CAM69975.1 - 0.28 11.3 7.6 32 4.9 0.0 5.9 6 0 0 6 6 6 0 HEAT repeat V-ATPase_H_N PF03224.9 CAM69975.1 - 0.41 9.7 5.2 2.3 7.2 0.0 3.2 2 2 0 3 3 3 0 V-ATPase subunit H RIIa PF02197.12 CAM69976.1 - 0.06 12.7 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit TnpV PF14198.1 CAM69976.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Transposon-encoded protein TnpV Pkinase PF00069.20 CAM69979.1 - 3.3e-70 236.1 0.0 4.7e-70 235.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM69979.1 - 4.9e-32 111.0 0.0 7.9e-32 110.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 CAM69979.1 - 0.00021 21.4 0.0 0.00044 20.4 0.0 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 CAM69979.1 - 0.00023 20.2 0.0 0.0006 18.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CAM69979.1 - 0.0082 15.2 0.0 0.019 14.0 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CAM69979.1 - 0.011 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family BCL_N PF04714.8 CAM69979.1 - 0.084 12.4 0.2 2 8.0 0.1 2.4 2 0 0 2 2 2 0 BCL7, N-terminal conserver region PFEMP PF03011.10 CAM69979.1 - 0.75 10.1 3.4 1.4 9.2 0.6 2.2 2 0 0 2 2 2 0 PFEMP DBL domain FeoB_C PF07664.7 CAM69980.1 - 0.0094 15.3 1.3 0.037 13.4 0.9 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B C terminus FlaG PF03646.10 CAM69980.1 - 0.13 12.4 0.3 0.23 11.5 0.2 1.4 1 0 0 1 1 1 0 FlaG protein UPF0233 PF06781.7 CAM69981.1 - 0.083 12.5 0.7 0.18 11.4 0.5 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) DUF3481 PF11980.3 CAM69981.1 - 0.63 9.9 2.1 0.48 10.2 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3481) Methyltransf_PK PF05891.7 CAM69982.1 - 4.3e-66 222.3 0.0 5.3e-66 222.0 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_11 PF08241.7 CAM69982.1 - 3.2e-11 43.5 0.0 5.1e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAM69982.1 - 1.3e-06 28.6 0.0 2.3e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAM69982.1 - 6.3e-06 25.8 0.0 9.2e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAM69982.1 - 8.6e-06 26.1 0.0 1.4e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAM69982.1 - 2.5e-05 24.8 0.0 4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAM69982.1 - 3.9e-05 23.4 0.0 6.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 CAM69982.1 - 0.00016 20.9 0.0 0.00018 20.7 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.9 CAM69982.1 - 0.0003 20.2 0.0 0.00053 19.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 CAM69982.1 - 0.014 15.4 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF2255 PF10012.4 CAM69982.1 - 0.02 14.8 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) DUF4105 PF13387.1 CAM69982.1 - 0.032 13.4 0.0 0.045 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) PRP1_N PF06424.7 CAM69983.1 - 0.48 10.7 0.1 0.48 10.7 0.0 2.7 3 0 0 3 3 3 0 PRP1 splicing factor, N-terminal Filament PF00038.16 CAM69983.1 - 1.7 8.0 23.1 0.035 13.5 3.0 2.9 3 1 0 3 3 3 0 Intermediate filament protein Fib_alpha PF08702.5 CAM69983.1 - 2 8.5 10.2 0.28 11.3 2.6 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Prefoldin_2 PF01920.15 CAM69984.1 - 5.8e-08 32.4 1.7 5.8e-08 32.4 1.2 1.7 1 1 0 1 1 1 1 Prefoldin subunit YgaB PF14182.1 CAM69984.1 - 0.28 11.4 6.5 3.9 7.7 0.5 2.3 2 0 0 2 2 2 0 YgaB-like protein Med30 PF11315.3 CAM69984.1 - 0.52 10.4 5.7 3.6 7.7 3.9 2.0 1 1 0 1 1 1 0 Mediator complex subunit 30 YkyA PF10368.4 CAM69984.1 - 0.79 9.0 6.6 1.6 8.0 1.5 2.1 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein DivIC PF04977.10 CAM69984.1 - 0.89 9.0 8.1 1.1 8.8 0.7 2.2 1 1 0 2 2 2 0 Septum formation initiator PEARLI-4 PF05278.7 CAM69984.1 - 6.2 6.1 9.5 2.7 7.2 0.7 2.1 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) OmpH PF03938.9 CAM69984.1 - 7.5 6.4 11.3 24 4.8 7.8 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) MMR_HSR1 PF01926.18 CAM69985.1 - 4.7e-08 33.0 0.0 8e-07 29.0 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 CAM69985.1 - 6.7e-05 22.5 0.0 0.0014 18.2 0.0 2.6 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 CAM69985.1 - 0.00019 20.9 0.0 0.0004 19.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CAM69985.1 - 0.00089 19.1 0.0 0.038 13.8 0.0 2.8 2 1 0 2 2 2 1 Dynamin family FeoB_N PF02421.13 CAM69985.1 - 0.0011 18.2 0.2 0.54 9.5 0.0 2.8 3 0 0 3 3 3 2 Ferrous iron transport protein B DUF258 PF03193.11 CAM69985.1 - 0.024 13.8 0.0 0.12 11.5 0.0 2.2 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Amastin PF07344.6 CAM69986.1 - 4.5e-41 140.0 8.5 5.3e-41 139.7 5.9 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF2628 PF10947.3 CAM69986.1 - 7.2 6.4 8.7 18 5.1 6.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2628) Amastin PF07344.6 CAM69987.1 - 3.4e-40 137.1 5.2 4.7e-40 136.7 3.6 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF914 PF06027.7 CAM69987.1 - 0.013 14.3 0.1 0.028 13.2 0.0 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) DUF3681 PF12442.3 CAM69987.1 - 0.028 14.5 0.2 0.071 13.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3681) Yip1 PF04893.12 CAM69987.1 - 0.038 13.4 10.1 0.024 14.1 4.8 1.9 2 0 0 2 2 2 0 Yip1 domain Pox_A14 PF05767.7 CAM69987.1 - 0.21 11.5 6.0 5 7.1 0.2 3.2 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 Claudin_2 PF13903.1 CAM69987.1 - 0.43 10.2 14.8 3 7.5 10.3 2.2 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction PfkB PF00294.19 CAM69988.1 - 2.5e-56 191.0 0.5 3e-56 190.7 0.3 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DAGK_cat PF00781.19 CAM69988.1 - 0.022 14.1 0.0 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain Nsp1 PF11501.3 CAM69988.1 - 0.15 11.9 0.0 12 5.7 0.0 3.0 3 0 0 3 3 3 0 Non structural protein Nsp1 HECT PF00632.20 CAM69991.1 - 2.1e-76 257.0 0.0 3e-76 256.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Cytochrom_B559 PF00283.14 CAM69991.1 - 3.6 6.9 9.3 0.64 9.3 0.2 3.1 3 0 0 3 3 3 0 Cytochrome b559, alpha (gene psbE) and beta (gene psbF)subunits Toxin_8 PF07365.7 CAM69992.1 - 0.0097 15.8 0.1 0.04 13.8 0.1 2.0 1 0 0 1 1 1 1 Alpha conotoxin precursor Apc3 PF12895.2 CAM69992.1 - 0.038 14.1 0.1 0.14 12.3 0.1 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4139 PF13598.1 CAM69993.1 - 1.3e-96 323.6 0.2 2e-96 323.0 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.1 CAM69993.1 - 5.2e-06 26.8 3.9 0.00038 20.8 0.8 2.6 2 0 0 2 2 2 2 N-terminal domain of unknown function (DUF4140) Cob_adeno_trans PF01923.13 CAM69993.1 - 0.007 16.1 0.5 16 5.2 0.0 3.2 3 0 0 3 3 3 2 Cobalamin adenosyltransferase IncA PF04156.9 CAM69993.1 - 0.027 14.0 0.2 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 IncA protein Matrilin_ccoil PF10393.4 CAM69993.1 - 3.3 7.1 10.5 2.9 7.3 0.4 2.9 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Spc97_Spc98 PF04130.8 CAM69994.1 - 1.9e-22 79.2 0.0 6.3e-22 77.5 0.0 1.8 1 1 0 1 1 1 1 Spc97 / Spc98 family RWP-RK PF02042.10 CAM69994.1 - 0.0053 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 RWP-RK domain DUF4214 PF13946.1 CAM69994.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4214) WD40 PF00400.27 CAM69995.1 - 5.4e-21 73.6 6.3 9.3e-09 34.8 0.3 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CAM69995.1 - 7.2e-14 51.4 0.0 1.5e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex MAM33 PF02330.11 CAM69997.1 - 1.8e-18 67.0 0.6 3.9e-17 62.6 1.3 1.8 1 1 1 2 2 2 2 Mitochondrial glycoprotein ABM PF03992.11 CAM69997.1 - 0.03 14.3 0.6 0.34 10.9 0.0 2.6 3 1 0 3 3 3 0 Antibiotic biosynthesis monooxygenase FGase PF05013.7 CAM69998.1 - 0.049 13.5 1.1 0.1 12.4 0.2 1.8 2 0 0 2 2 2 0 N-formylglutamate amidohydrolase APG5 PF04106.7 CAM69998.1 - 0.076 12.4 0.0 0.4 10.1 0.0 1.9 2 0 0 2 2 2 0 Autophagy protein Apg5 Pkinase PF00069.20 CAM70000.1 - 3.3e-35 121.5 0.0 5.6e-13 48.6 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CAM70000.1 - 5.9e-22 77.9 0.0 1.9e-13 50.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CAM70000.1 - 0.053 12.4 0.0 0.39 9.6 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Ufd2P_core PF10408.4 CAM70001.1 - 9.2e-127 423.8 0.0 1.2e-126 423.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core Thioredoxin PF00085.15 CAM70001.1 - 4.8e-22 77.6 0.0 1e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CAM70001.1 - 4.3e-05 23.6 0.1 0.00014 22.0 0.1 1.9 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CAM70001.1 - 5.2e-05 23.2 0.1 0.0077 16.3 0.0 2.6 1 1 1 2 2 2 1 Thioredoxin-like U-box PF04564.10 CAM70001.1 - 0.00043 20.1 0.2 0.0037 17.2 0.1 2.7 2 1 0 2 2 2 1 U-box domain Thioredoxin_7 PF13899.1 CAM70001.1 - 0.00049 20.0 0.2 0.0014 18.6 0.1 1.8 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 CAM70001.1 - 0.004 16.7 0.0 0.011 15.2 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 CAM70001.1 - 0.032 13.9 0.1 0.14 11.8 0.1 2.0 1 1 1 2 2 2 0 AhpC/TSA family DnaJ PF00226.26 CAM70003.1 - 0.0011 18.7 0.0 0.0021 17.7 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Herpes_capsid PF06112.6 CAM70003.1 - 0.012 15.6 2.9 0.012 15.6 2.0 2.7 3 0 0 3 3 3 0 Gammaherpesvirus capsid protein DUF1183 PF06682.7 CAM70003.1 - 0.52 9.8 9.5 0.71 9.4 2.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1183) Mito_carr PF00153.22 CAM70005.1 - 3.2e-49 164.5 3.2 2.6e-18 65.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RF-1 PF00472.15 CAM70006.1 - 1.3e-16 60.3 0.0 2e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.4 CAM70006.1 - 0.021 14.8 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit protein TRF PF08558.5 CAM70006.1 - 0.022 14.0 0.0 0.032 13.5 0.0 1.1 1 0 0 1 1 1 0 Telomere repeat binding factor (TRF) Sdh5 PF03937.11 CAM70007.1 - 1.8e-19 69.1 0.7 3.2e-19 68.3 0.5 1.4 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase IQ PF00612.22 CAM70008.1 - 7e-07 28.3 20.2 0.0041 16.6 0.2 5.0 5 0 0 5 5 5 4 IQ calmodulin-binding motif WW PF00397.21 CAM70009.1 - 2e-10 40.2 2.4 3.9e-10 39.4 1.7 1.5 1 0 0 1 1 1 1 WW domain ATG16 PF08614.6 CAM70009.1 - 0.017 14.9 0.8 0.059 13.1 0.0 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DREV PF05219.7 CAM70010.1 - 1.2e-63 214.5 0.0 1.4e-63 214.2 0.0 1.0 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_23 PF13489.1 CAM70010.1 - 5.1e-13 49.0 0.0 7.2e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAM70010.1 - 1.3e-11 44.7 0.0 2.4e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CAM70010.1 - 5.4e-10 39.6 0.0 9.7e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAM70010.1 - 7.6e-08 32.9 0.0 1.4e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAM70010.1 - 1.1e-05 25.0 0.0 5.7e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CAM70010.1 - 0.0053 16.7 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 CAM70010.1 - 0.0085 15.1 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase CheR PF01739.13 CAM70010.1 - 0.01 15.0 0.1 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_25 PF13649.1 CAM70010.1 - 0.012 15.9 0.0 0.053 13.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 CAM70010.1 - 0.078 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain RRM_1 PF00076.17 CAM70011.1 - 2.2e-22 78.4 0.0 1.6e-09 37.2 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM70011.1 - 4.1e-15 55.5 0.0 1.6e-05 24.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM70011.1 - 7.6e-12 44.8 0.0 0.0038 17.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 CAM70011.1 - 0.016 15.2 0.0 0.61 10.1 0.0 2.5 2 0 0 2 2 2 0 RNA binding domain Nup35_RRM_2 PF14605.1 CAM70011.1 - 0.021 14.5 0.1 6.1 6.7 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Arm PF00514.18 CAM70012.1 - 1e-67 221.8 20.6 4.7e-10 38.9 0.0 9.1 10 0 0 10 10 10 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CAM70012.1 - 1e-19 70.6 1.9 1e-05 25.7 0.2 5.4 1 1 3 5 5 5 5 HEAT repeats HEAT_EZ PF13513.1 CAM70012.1 - 5.5e-17 61.7 9.4 0.00049 20.4 0.1 6.4 6 2 2 8 8 8 4 HEAT-like repeat HEAT PF02985.17 CAM70012.1 - 1.2e-12 46.7 11.7 0.051 13.6 0.0 8.1 9 0 0 9 9 9 5 HEAT repeat Arm_2 PF04826.8 CAM70012.1 - 0.00014 21.1 0.0 0.021 13.9 0.0 3.5 3 1 1 4 4 4 1 Armadillo-like V-ATPase_H_C PF11698.3 CAM70012.1 - 0.00052 19.9 0.0 54 3.7 0.0 4.8 3 2 0 4 4 4 0 V-ATPase subunit H Proteasom_PSMB PF10508.4 CAM70012.1 - 0.0021 16.4 0.0 0.0034 15.7 0.0 1.3 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit Adaptin_N PF01602.15 CAM70012.1 - 0.079 11.2 0.0 0.39 8.9 0.0 2.3 1 1 1 2 2 2 0 Adaptin N terminal region PgaD PF13994.1 CAM70013.1 - 0.12 11.9 0.1 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 PgaD-like protein MA3 PF02847.12 CAM70015.1 - 2.1e-07 30.6 0.1 7.3e-07 28.8 0.0 2.0 2 0 0 2 2 2 1 MA3 domain Peptidase_S64 PF08192.6 CAM70015.1 - 0.028 12.7 0.9 0.046 12.0 0.6 1.2 1 0 0 1 1 1 0 Peptidase family S64 MIF4G PF02854.14 CAM70015.1 - 0.15 11.4 0.0 0.53 9.6 0.0 2.0 1 1 0 1 1 1 0 MIF4G domain zf-DHHC PF01529.15 CAM70017.1 - 1.7e-41 141.5 0.3 2.7e-41 140.8 0.2 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase TMEM107 PF14995.1 CAM70018.1 - 1.6e-36 125.1 8.7 2.1e-36 124.7 6.0 1.1 1 0 0 1 1 1 1 Transmembrane protein Cupin_8 PF13621.1 CAM70019.1 - 3.7e-21 75.7 0.0 1.2e-20 74.0 0.0 1.7 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 CAM70019.1 - 1.5e-09 38.0 0.1 2.2e-06 27.9 0.0 2.4 2 0 0 2 2 2 2 JmjC domain, hydroxylase Cupin_2 PF07883.6 CAM70019.1 - 0.00079 18.8 0.2 0.021 14.3 0.0 2.4 2 0 0 2 2 2 1 Cupin domain Cupin_4 PF08007.7 CAM70019.1 - 0.0019 17.5 0.0 0.0031 16.8 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein F-box-like PF12937.2 CAM70019.1 - 1.2 8.9 8.4 0.091 12.5 1.4 2.7 3 0 0 3 3 3 0 F-box-like UCH PF00443.24 CAM70020.1 - 4.6e-41 140.7 0.1 7.9e-41 139.9 0.0 1.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CAM70020.1 - 1e-06 28.4 4.3 0.017 14.5 0.4 2.8 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CAM70020.1 - 4.6 7.4 15.7 0.031 14.3 0.8 3.9 4 0 0 4 4 4 0 Zn-finger in ubiquitin-hydrolases and other protein LSM PF01423.17 CAM70021.1 - 1.7e-14 53.1 0.1 1.9e-14 52.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain AAA_28 PF13521.1 CAM70022.1 - 5.9e-19 68.6 0.0 1e-18 67.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 CAM70022.1 - 0.0045 15.8 0.0 0.0079 15.0 0.0 1.3 1 0 0 1 1 1 1 ArgK protein AAA_29 PF13555.1 CAM70022.1 - 0.0086 15.5 0.1 0.14 11.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF4066 PF13278.1 CAM70022.1 - 0.01 15.0 0.0 0.023 13.9 0.0 1.6 1 0 0 1 1 1 0 Putative amidotransferase AAA_17 PF13207.1 CAM70022.1 - 0.014 16.2 0.0 0.029 15.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.4 CAM70022.1 - 0.038 12.9 0.0 0.067 12.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 zf-C3HC4_3 PF13920.1 CAM70023.1 - 5e-09 35.7 13.4 5e-09 35.7 9.3 3.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAM70023.1 - 9.9e-05 22.2 15.9 9.9e-05 22.2 11.0 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CAM70023.1 - 0.00035 20.3 15.3 0.00035 20.3 10.6 3.2 3 0 0 3 3 3 1 Ring finger domain DUF1908 PF08926.6 CAM70023.1 - 0.051 12.3 0.0 0.051 12.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1908) Rtf2 PF04641.7 CAM70023.1 - 1.3 8.1 8.5 3.3 6.8 1.5 2.6 2 0 0 2 2 2 0 Rtf2 RING-finger Menin PF05053.8 CAM70023.1 - 1.9 6.5 9.5 3.6 5.6 6.6 1.4 1 0 0 1 1 1 0 Menin Phos_pyr_kin PF08543.7 CAM70025.1 - 2.1e-17 63.1 0.0 2.8e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 CAM70025.1 - 6.3e-12 45.2 3.2 2.6e-09 36.6 1.1 2.7 2 1 0 2 2 2 2 pfkB family carbohydrate kinase Acetyltransf_1 PF00583.19 CAM70026.1 - 1.7e-05 24.7 0.1 0.00016 21.6 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CAM70026.1 - 0.00026 21.0 0.1 0.0019 18.3 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CAM70026.1 - 0.0005 19.9 0.0 0.0045 16.8 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CAM70026.1 - 0.0025 17.5 0.1 0.081 12.6 0.0 2.3 2 0 0 2 2 2 1 FR47-like protein CENP-F_leu_zip PF10473.4 CAM70028.1 - 7.5e-05 22.6 1.4 7.5e-05 22.6 0.9 3.9 4 1 0 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 CAM70028.1 - 0.002 17.3 7.9 0.11 11.6 0.3 2.6 1 1 2 3 3 3 3 Reovirus sigma C capsid protein TMF_DNA_bd PF12329.3 CAM70028.1 - 0.0061 16.3 0.7 0.0061 16.3 0.5 5.2 4 2 1 5 5 5 1 TATA element modulatory factor 1 DNA binding Seryl_tRNA_N PF02403.17 CAM70028.1 - 0.02 14.9 0.3 0.02 14.9 0.2 4.6 4 1 0 5 5 5 0 Seryl-tRNA synthetase N-terminal domain AAA_23 PF13476.1 CAM70028.1 - 0.26 11.5 7.5 1.1 9.5 5.2 2.0 1 1 0 1 1 1 0 AAA domain Fib_alpha PF08702.5 CAM70028.1 - 0.85 9.7 8.6 7.6 6.6 0.1 3.6 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family Mito_fiss_reg PF05308.6 CAM70028.1 - 2.9 7.2 13.4 0.097 12.0 0.8 3.6 3 1 1 4 4 4 0 Mitochondrial fission regulator NPV_P10 PF05531.7 CAM70028.1 - 3.2 8.0 14.4 17 5.7 0.4 4.7 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF802 PF05650.6 CAM70028.1 - 9.2 6.4 24.2 0.79 9.8 4.1 4.1 2 1 0 2 2 2 0 Domain of unknown function (DUF802) Clathrin PF00637.15 CAM70029.1 - 6.2e-09 35.5 0.1 2.1e-07 30.6 0.2 2.3 2 0 0 2 2 2 1 Region in Clathrin and VPS zf-RING_2 PF13639.1 CAM70029.1 - 2.1e-05 24.2 1.6 8.3e-05 22.3 1.1 2.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CAM70029.1 - 0.0014 18.6 0.9 0.0048 16.8 0.6 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CAM70029.1 - 0.02 14.5 0.5 0.058 13.0 0.3 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CAM70029.1 - 0.045 13.8 0.2 0.16 12.1 0.2 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_6 PF14835.1 CAM70029.1 - 0.13 12.1 0.1 0.4 10.4 0.1 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 CAM70029.1 - 0.23 11.2 3.4 0.17 11.6 0.4 2.3 2 0 0 2 2 2 0 zinc-RING finger domain Brix PF04427.13 CAM70030.1 - 1.1e-45 155.7 0.4 1.4e-45 155.3 0.3 1.1 1 0 0 1 1 1 1 Brix domain SNF2_N PF00176.18 CAM70031.1 - 2.4e-49 167.7 0.0 3.5e-49 167.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CAM70031.1 - 1.7e-07 30.9 0.0 4e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAM70031.1 - 0.024 14.4 0.0 2.3 7.9 0.0 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2360 PF10152.4 CAM70031.1 - 1.7 8.8 7.0 28 4.9 4.9 2.9 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) ABC_tran PF00005.22 CAM70033.1 - 3.1e-19 69.6 0.5 1e-12 48.4 0.4 3.1 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CAM70033.1 - 8.6e-11 42.3 0.3 4.7e-05 23.4 0.1 3.0 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.14 CAM70033.1 - 4.2e-06 26.1 0.1 0.0085 15.3 0.1 2.9 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 CAM70033.1 - 0.00083 18.5 0.0 0.0017 17.5 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 CAM70033.1 - 0.0012 18.3 0.0 0.0027 17.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 CAM70033.1 - 0.0032 16.5 0.1 0.67 8.9 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.1 CAM70033.1 - 0.0067 16.4 1.0 0.097 12.6 0.7 2.4 1 1 0 1 1 1 1 AAA domain Dynamin_N PF00350.18 CAM70033.1 - 0.085 12.6 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Dynamin family AAA_25 PF13481.1 CAM70033.1 - 0.087 12.2 0.1 0.83 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 CAM70033.1 - 0.095 12.1 0.1 0.21 11.0 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.1 CAM70033.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 CAM70033.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein AAA_22 PF13401.1 CAM70033.1 - 0.15 12.1 1.1 2.1 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 CAM70033.1 - 0.18 11.2 0.7 2.4 7.5 0.0 2.5 3 0 0 3 3 3 0 IstB-like ATP binding protein RabGAP-TBC PF00566.13 CAM70035.1 - 7e-35 120.4 0.2 1.2e-34 119.7 0.2 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Sporozoite_P67 PF05642.6 CAM70035.1 - 2 6.1 7.3 3.5 5.3 5.0 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RIO1 PF01163.17 CAM70036.1 - 4e-45 153.5 0.0 7.4e-45 152.6 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 CAM70036.1 - 2.2e-32 110.9 0.4 4.9e-31 106.6 0.2 2.3 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.18 CAM70036.1 - 4.6e-10 39.6 0.1 3.8e-05 23.5 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CAM70036.1 - 0.0032 16.5 4.3 0.0049 15.9 0.0 3.0 3 1 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family PSP1 PF04468.7 CAM70037.1 - 5.2e-07 29.5 0.1 9.5e-07 28.7 0.1 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Peptidase_M20 PF01546.23 CAM70038.1 - 3.9e-26 91.7 0.1 5e-26 91.3 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CAM70038.1 - 7.9e-08 32.0 0.1 1.8e-07 30.9 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 CAM70038.1 - 0.0059 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PLAC8 PF04749.12 CAM70039.1 - 1.8e-20 73.4 13.4 2.8e-20 72.8 9.3 1.3 1 0 0 1 1 1 1 PLAC8 family WD40 PF00400.27 CAM70040.1 - 2.9e-29 99.8 2.4 4.4e-06 26.3 0.2 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CAM70040.1 - 0.044 11.9 0.3 4 5.4 0.1 2.8 2 1 1 3 3 3 0 Nucleoporin Nup120/160 PQQ_3 PF13570.1 CAM70040.1 - 0.27 11.5 1.9 1.8e+02 2.5 0.0 5.1 6 0 0 6 6 6 0 PQQ-like domain ABC_tran PF00005.22 CAM70047.1 - 3.6e-22 79.1 0.0 7.3e-08 32.8 0.0 4.7 4 0 0 4 4 4 4 ABC transporter ABC_membrane PF00664.18 CAM70047.1 - 1.2e-16 61.0 8.5 1.4e-08 34.5 5.3 2.7 2 0 0 2 2 2 2 ABC transporter transmembrane region DUF258 PF03193.11 CAM70047.1 - 0.072 12.2 0.2 0.78 8.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Cu-oxidase_2 PF07731.9 CAM70047.1 - 0.36 10.3 0.1 0.71 9.3 0.1 1.3 1 0 0 1 1 1 0 Multicopper oxidase UPF0079 PF02367.12 CAM70047.1 - 0.68 9.5 0.0 1.3 8.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 cobW PF02492.14 CAM70047.1 - 0.73 9.2 0.2 1.4 8.3 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.4 CAM70047.1 - 0.73 8.7 0.2 1.1 8.1 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Dynamin_N PF00350.18 CAM70047.1 - 2.3 8.0 6.9 0.62 9.8 1.4 2.4 3 0 0 3 3 3 0 Dynamin family AAA_23 PF13476.1 CAM70047.1 - 9.3 6.5 0.0 16 5.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Kinesin PF00225.18 CAM70048.1 - 5.9e-82 275.0 0.0 5.9e-82 275.0 0.0 1.5 2 0 0 2 2 2 1 Kinesin motor domain Mcp5_PH PF12814.2 CAM70048.1 - 0.00021 21.2 0.0 0.00056 19.8 0.0 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology AAA_13 PF13166.1 CAM70048.1 - 0.047 12.1 11.2 0.097 11.1 7.2 1.8 2 0 0 2 2 2 0 AAA domain Bap31 PF05529.7 CAM70048.1 - 1.1 8.7 10.1 2.7 7.3 7.0 1.6 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like V_ATPase_I PF01496.14 CAM70048.1 - 1.1 7.0 7.0 1.6 6.5 4.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 CAM70048.1 - 1.3 8.0 11.9 3.2 6.7 8.3 1.6 1 0 0 1 1 1 0 Autophagy protein Apg6 S1-P1_nuclease PF02265.11 CAM70049.1 - 4.5e-61 206.6 0.0 5.1e-61 206.4 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease PseudoU_synth_2 PF00849.17 CAM70050.1 - 1.6e-31 109.3 0.0 2.3e-30 105.6 0.0 2.1 1 1 0 1 1 1 1 RNA pseudouridylate synthase DUF2109 PF09882.4 CAM70050.1 - 0.028 14.3 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2109) Rad17 PF03215.10 CAM70051.1 - 6.8e-08 31.6 0.1 0.00019 20.2 0.0 3.0 3 0 0 3 3 3 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 CAM70051.1 - 0.033 13.2 0.0 0.057 12.4 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Flavoprotein PF02441.14 CAM70052.1 - 2.3e-43 146.9 1.0 4e-43 146.1 0.7 1.4 1 0 0 1 1 1 1 Flavoprotein Chorion_2 PF03964.10 CAM70052.1 - 0.032 14.7 1.6 0.054 14.0 1.1 1.4 1 0 0 1 1 1 0 Chorion family 2 PseudoU_synth_1 PF01416.15 CAM70054.1 - 2.6e-27 95.3 0.0 3.3e-19 69.2 0.0 2.6 2 0 0 2 2 2 2 tRNA pseudouridine synthase Pkinase PF00069.20 CAM70055.2 - 4.6e-30 104.6 0.0 1e-12 47.7 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CAM70055.2 - 2.8e-15 56.1 0.0 3e-06 26.4 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.1 CAM70055.2 - 0.3 9.9 0.1 0.63 8.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like DUF1796 PF08795.5 CAM70056.1 - 1.4e-65 220.0 0.0 2.9e-65 218.9 0.0 1.6 2 0 0 2 2 2 1 Putative papain-like cysteine peptidase (DUF1796) Kelch_4 PF13418.1 CAM70057.1 - 5.6e-07 29.2 2.8 0.22 11.3 0.0 5.6 5 0 0 5 5 5 2 Galactose oxidase, central domain PH PF00169.24 CAM70057.1 - 0.00017 21.7 2.0 0.011 15.9 0.1 2.9 2 1 0 2 2 2 1 PH domain Kelch_3 PF13415.1 CAM70057.1 - 0.00021 21.3 0.7 15 5.8 0.0 5.9 5 1 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.20 CAM70057.1 - 0.0033 16.9 0.9 0.69 9.4 0.1 4.0 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 CAM70057.1 - 0.047 13.6 5.9 23 5.0 0.0 5.2 7 0 0 7 7 7 0 Kelch motif PH_11 PF15413.1 CAM70057.1 - 0.2 11.9 1.6 2.1 8.6 0.2 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain Actin PF00022.14 CAM70059.1 - 0.00067 18.1 0.0 0.0015 17.0 0.0 1.5 2 0 0 2 2 2 1 Actin DNA_pol_viral_N PF00242.12 CAM70059.1 - 0.62 9.0 7.3 1.2 8.0 5.1 1.4 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain NAD_binding_6 PF08030.7 CAM70060.1 - 7.4e-17 61.6 0.1 1.6e-08 34.6 0.0 2.7 2 1 0 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 CAM70060.1 - 2.2e-12 47.1 12.2 2.2e-12 47.1 8.5 2.8 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 CAM70060.1 - 2.7e-10 40.0 0.0 6e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.19 CAM70060.1 - 0.0015 18.5 0.0 0.0048 17.0 0.0 1.9 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 CAM70060.1 - 0.023 15.2 0.0 1.5 9.3 0.0 2.6 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF1077 PF06417.7 CAM70063.1 - 1.3e-42 144.0 1.8 1.6e-42 143.7 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) DUF1212 PF06738.7 CAM70063.1 - 0.037 13.5 0.7 0.085 12.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1212) HSP33 PF01430.14 CAM70064.1 - 2.2e-10 40.1 0.0 2.5e-05 23.5 0.0 2.2 2 0 0 2 2 2 2 Hsp33 protein CRAL_TRIO PF00650.15 CAM70065.1 - 9.3e-22 77.2 0.0 1.2e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CAM70065.1 - 4.1e-06 26.8 0.1 5.8e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 CAM70065.1 - 9.6e-05 22.3 0.0 0.00015 21.7 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain FLO_LFY PF01698.11 CAM70066.1 - 0.082 11.7 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein AAA_2 PF07724.9 CAM70067.1 - 3.5e-07 30.2 0.0 5.9e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CAM70067.1 - 4.5e-06 26.8 0.0 1.9e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CAM70067.1 - 4e-05 23.3 0.0 0.0001 22.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CAM70067.1 - 0.00072 19.5 0.1 0.053 13.5 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain AAA PF00004.24 CAM70067.1 - 0.0021 18.2 0.0 0.0044 17.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF3154 PF11351.3 CAM70067.1 - 0.014 15.1 1.6 0.55 9.9 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3154) AAA_17 PF13207.1 CAM70067.1 - 0.043 14.6 0.0 0.12 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CAM70067.1 - 0.1 12.4 3.0 0.15 11.9 0.0 2.8 5 0 0 5 5 5 0 AAA domain RNA_helicase PF00910.17 CAM70067.1 - 0.25 11.5 0.0 0.53 10.4 0.0 1.6 1 1 0 1 1 1 0 RNA helicase Ras PF00071.17 CAM70068.1 - 5.3e-38 129.9 0.0 6.5e-38 129.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAM70068.1 - 2.6e-14 53.7 0.0 5.2e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAM70068.1 - 1.2e-10 40.8 0.0 1.6e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CAM70068.1 - 0.0017 17.5 0.0 0.0023 17.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 CAM70068.1 - 0.0036 16.5 0.0 2 7.6 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B MMR_HSR1 PF01926.18 CAM70068.1 - 0.0097 15.8 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 CAM70068.1 - 0.011 14.5 0.0 1.1 7.8 0.0 2.3 2 1 1 3 3 3 0 G-protein alpha subunit Ribonuc_red_lgN PF00317.16 CAM70068.1 - 0.035 13.9 0.1 0.073 12.8 0.1 1.5 1 1 0 1 1 1 0 Ribonucleotide reductase, all-alpha domain IncA PF04156.9 CAM70070.1 - 0.00052 19.6 16.1 0.021 14.4 3.9 2.2 2 0 0 2 2 2 2 IncA protein CENP-F_leu_zip PF10473.4 CAM70070.1 - 0.47 10.2 26.3 2.6 7.9 8.5 3.0 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.3 CAM70070.1 - 1.2 9.0 27.6 0.22 11.4 5.4 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.10 CAM70070.1 - 1.6 8.2 25.2 0.11 11.9 2.0 3.3 2 1 1 3 3 3 0 Septum formation initiator APG6 PF04111.7 CAM70070.1 - 4.5 6.2 20.3 1.6 7.6 2.8 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 Peptidase_S64 PF08192.6 CAM70070.1 - 6.1 5.0 6.8 2.8 6.1 0.2 2.0 2 0 0 2 2 2 0 Peptidase family S64 DUF342 PF03961.8 CAM70070.1 - 9.8 4.4 10.8 1.6 7.0 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF342) CLASP_N PF12348.3 CAM70073.1 - 4.4e-11 42.5 5.2 3.6e-07 29.7 0.0 4.7 5 0 0 5 5 5 2 CLASP N terminal Cnd1 PF12717.2 CAM70073.1 - 1.6 8.5 5.2 2 8.2 0.8 3.2 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 IFT46_B_C PF12317.3 CAM70074.1 - 8.5e-92 306.3 0.5 1.1e-91 305.9 0.3 1.2 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal Sigma70_ner PF04546.8 CAM70074.1 - 0.026 14.1 1.9 0.044 13.3 1.3 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 CAM70074.1 - 0.034 13.6 3.1 0.047 13.1 2.2 1.2 1 0 0 1 1 1 0 Nucleoplasmin Voldacs PF03517.8 CAM70074.1 - 0.054 13.3 1.6 0.11 12.3 1.1 1.4 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling Myc_N PF01056.13 CAM70074.1 - 0.87 8.6 4.7 1.3 8.0 3.2 1.2 1 0 0 1 1 1 0 Myc amino-terminal region PBP1_TM PF14812.1 CAM70074.1 - 1.3 9.3 6.2 2.3 8.6 4.3 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pkinase PF00069.20 CAM70075.1 - 1.4e-30 106.3 0.0 1.3e-28 99.8 0.0 2.9 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAM70075.1 - 1.6e-08 33.9 0.0 2.1e-05 23.7 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CAM70075.1 - 0.0013 18.4 0.0 0.0033 17.1 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family DnaJ PF00226.26 CAM70076.1 - 5e-20 71.0 0.6 1.7e-19 69.2 0.1 2.2 2 0 0 2 2 2 1 DnaJ domain TGT PF01702.13 CAM70077.1 - 4.1e-87 291.4 0.0 5.5e-87 290.9 0.0 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase PapD-like PF14874.1 CAM70078.1 - 4.8e-22 77.8 27.8 0.00035 20.4 0.1 14.7 18 0 0 18 18 16 4 Flagellar-associated PapD-like Motile_Sperm PF00635.21 CAM70078.1 - 6.9e-14 51.4 7.6 0.37 10.4 0.0 12.8 14 0 0 14 14 14 3 MSP (Major sperm protein) domain MYCBPAP PF14646.1 CAM70078.1 - 3.2e-07 29.4 0.0 2.6 6.6 0.0 7.1 9 0 0 9 9 9 2 MYCBP-associated protein family Zeta_toxin PF06414.7 CAM70078.1 - 1.4e-06 27.5 0.1 3.9e-06 26.0 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 CAM70078.1 - 3.6e-06 26.9 0.6 1.2e-05 25.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CAM70078.1 - 4.3e-05 24.3 0.0 9.1e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain PapD_N PF00345.15 CAM70078.1 - 9.1e-05 22.2 0.7 0.21 11.4 0.0 5.4 5 0 0 5 5 5 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain KTI12 PF08433.5 CAM70078.1 - 0.002 17.4 0.0 0.0036 16.5 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 NACHT PF05729.7 CAM70078.1 - 0.0027 17.3 0.0 0.019 14.6 0.0 2.2 1 1 0 1 1 1 1 NACHT domain FixG_C PF11614.3 CAM70078.1 - 0.0049 16.9 1.0 1.5e+02 2.4 0.0 6.9 7 0 0 7 7 6 0 IG-like fold at C-terminal of FixG, putative oxidoreductase AAA_22 PF13401.1 CAM70078.1 - 0.02 15.0 0.0 0.056 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CAM70078.1 - 0.074 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Trigger_C PF05698.9 CAM70078.1 - 0.085 12.6 1.7 0.15 11.8 1.2 1.3 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus AAA PF00004.24 CAM70078.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 CAM70078.1 - 0.2 11.9 0.0 0.4 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 CAM70078.1 - 1.4 8.4 0.0 2.6 7.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 CAM70078.1 - 3.6 6.3 0.0 6.2 5.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Arch_ATPase PF01637.13 CAM70078.1 - 5.3 6.6 0.0 10 5.7 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase DUF3449 PF11931.3 CAM70079.1 - 4.8e-45 153.4 0.8 1.3e-44 152.0 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) FYVE PF01363.16 CAM70081.1 - 4.7e-12 45.6 8.7 8.1e-12 44.8 3.8 2.8 2 0 0 2 2 2 1 FYVE zinc finger PI3_PI4_kinase PF00454.22 CAM70081.1 - 2.7e-09 36.8 0.4 4.5e-07 29.5 0.0 2.4 2 0 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase AAA_18 PF13238.1 CAM70085.1 - 7e-25 87.8 0.1 1.1e-24 87.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CAM70085.1 - 2e-11 44.7 0.1 4.1e-11 43.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CAM70085.1 - 1.9e-06 27.7 0.2 0.00025 20.9 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 CAM70085.1 - 1.3e-05 25.3 0.5 2.7e-05 24.3 0.4 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CAM70085.1 - 7.2e-05 22.8 2.3 0.00046 20.1 1.6 2.2 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CAM70085.1 - 0.00031 19.8 0.0 0.00049 19.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus ADK PF00406.17 CAM70085.1 - 0.0011 18.8 0.1 0.21 11.4 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase AAA_22 PF13401.1 CAM70085.1 - 0.0011 19.0 0.0 0.0017 18.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CAM70085.1 - 0.0014 17.7 0.2 0.0027 16.8 0.0 1.7 2 1 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 CAM70085.1 - 0.0015 18.2 0.0 0.0041 16.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 CAM70085.1 - 0.0025 16.8 0.1 0.0034 16.4 0.1 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SKI PF01202.17 CAM70085.1 - 0.0026 17.6 4.6 0.028 14.3 3.2 2.2 1 1 0 1 1 1 1 Shikimate kinase Parvo_NS1 PF01057.12 CAM70085.1 - 0.0055 15.6 0.0 0.011 14.6 0.0 1.5 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_16 PF13191.1 CAM70085.1 - 0.0061 16.5 0.0 0.018 15.0 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 CAM70085.1 - 0.0065 16.1 0.0 0.019 14.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 CAM70085.1 - 0.0067 16.0 0.1 0.014 14.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 CAM70085.1 - 0.0083 15.8 2.6 0.017 14.8 0.1 2.4 1 1 1 3 3 3 1 NTPase ABC_tran PF00005.22 CAM70085.1 - 0.0096 16.2 1.7 0.066 13.5 1.2 2.0 1 1 0 1 1 1 1 ABC transporter RNA_helicase PF00910.17 CAM70085.1 - 0.011 15.9 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase CoaE PF01121.15 CAM70085.1 - 0.012 15.0 0.6 0.41 10.0 0.1 2.2 2 0 0 2 2 2 0 Dephospho-CoA kinase Mg_chelatase PF01078.16 CAM70085.1 - 0.013 14.7 0.1 0.044 12.9 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 CAM70085.1 - 0.014 14.5 1.3 0.017 14.2 0.1 1.7 2 0 0 2 2 2 0 KaiC dNK PF01712.14 CAM70085.1 - 0.016 15.1 0.1 0.026 14.4 0.1 1.5 1 1 0 1 1 1 0 Deoxynucleoside kinase TIP49 PF06068.8 CAM70085.1 - 0.016 13.9 0.0 0.028 13.1 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus IstB_IS21 PF01695.12 CAM70085.1 - 0.016 14.6 0.3 0.037 13.4 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein KTI12 PF08433.5 CAM70085.1 - 0.017 14.3 0.1 0.046 12.9 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Sigma54_activat PF00158.21 CAM70085.1 - 0.018 14.5 0.0 0.044 13.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Torsin PF06309.6 CAM70085.1 - 0.026 14.4 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 Torsin CPT PF07931.7 CAM70085.1 - 0.034 13.7 3.4 0.52 9.9 0.0 2.9 2 1 1 3 3 3 0 Chloramphenicol phosphotransferase-like protein AAA_14 PF13173.1 CAM70085.1 - 0.035 14.0 0.1 0.087 12.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 CAM70085.1 - 0.041 12.8 0.0 0.063 12.2 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain Cytidylate_kin2 PF13189.1 CAM70085.1 - 0.055 13.3 0.9 0.54 10.1 0.1 2.4 1 1 1 2 2 2 0 Cytidylate kinase-like family AAA_25 PF13481.1 CAM70085.1 - 0.056 12.8 0.0 0.19 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 CAM70085.1 - 0.062 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 CAM70085.1 - 0.066 12.1 0.0 0.12 11.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.14 CAM70085.1 - 0.082 12.3 0.2 0.42 10.0 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Sars6 PF12133.3 CAM70085.1 - 0.094 12.4 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Open reading frame 6 from SARS coronavirus NACHT PF05729.7 CAM70085.1 - 0.1 12.2 0.1 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ATP-synt_ab PF00006.20 CAM70085.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain APS_kinase PF01583.15 CAM70085.1 - 0.11 12.1 0.0 0.34 10.5 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase MobB PF03205.9 CAM70085.1 - 0.15 11.7 1.1 0.39 10.4 0.0 2.1 2 2 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 CAM70085.1 - 0.17 11.3 1.1 0.33 10.3 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family Thymidylate_kin PF02223.12 CAM70085.1 - 0.17 11.2 2.7 5.1 6.4 0.0 2.3 1 1 1 2 2 2 0 Thymidylate kinase AAA_23 PF13476.1 CAM70085.1 - 0.48 10.7 3.0 2.3 8.4 2.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CAM70085.1 - 1.2 8.5 3.3 1.4 8.2 0.1 1.9 1 1 1 2 2 2 0 AAA-like domain Elf1 PF05129.8 CAM70087.1 - 0.052 13.2 0.6 0.12 12.0 0.4 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like FYVE PF01363.16 CAM70087.1 - 1 9.3 7.7 0.48 10.3 0.0 2.6 2 1 0 2 2 2 0 FYVE zinc finger CoA_trans PF01144.18 CAM70088.1 - 7.1e-102 339.1 0.0 8.2e-62 208.2 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 CAM70088.1 - 0.047 13.3 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain CoA_trans PF01144.18 CAM70089.1 - 3.4e-100 333.6 1.1 7e-63 211.7 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 CAM70089.1 - 1.2e-05 25.0 0.0 2.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Ala_racemase_C PF00842.16 CAM70089.1 - 0.11 11.9 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 Alanine racemase, C-terminal domain PseudoU_synth_2 PF00849.17 CAM70091.1 - 6.5e-21 74.8 0.3 1.7e-12 47.5 0.1 2.6 2 0 0 2 2 2 2 RNA pseudouridylate synthase S4 PF01479.20 CAM70091.1 - 0.009 15.4 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 S4 domain TPR_MLP1_2 PF07926.7 CAM70092.1 - 1.9 8.2 22.3 0.33 10.7 1.1 3.5 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein zf-C2H2_2 PF12756.2 CAM70094.1 - 1.1e-19 70.4 7.6 8.6e-14 51.4 1.0 2.2 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 CAM70094.1 - 4.5e-05 23.4 12.1 0.0029 17.7 0.4 4.0 3 1 1 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 CAM70094.1 - 0.0014 18.7 8.0 1.1 9.6 0.0 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CAM70094.1 - 0.06 13.7 10.0 0.34 11.3 0.0 4.7 4 1 0 4 4 4 0 Zinc finger, C2H2 type PC_rep PF01851.17 CAM70096.1 - 0.00048 20.2 6.6 30 5.0 0.0 6.8 7 0 0 7 7 7 2 Proteasome/cyclosome repeat IFT20 PF14931.1 CAM70097.1 - 5.5e-39 132.7 8.8 6.2e-39 132.6 6.1 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 VQ PF05678.9 CAM70097.1 - 0.06 12.3 2.5 1.3 8.1 0.1 2.7 3 0 0 3 3 3 0 VQ motif 4HB_MCP_1 PF12729.2 CAM70097.1 - 0.12 11.6 3.4 0.15 11.3 1.9 1.5 1 1 0 1 1 1 0 Four helix bundle sensory module for signal transduction Snapin_Pallidin PF14712.1 CAM70097.1 - 0.48 10.7 7.1 1.5 9.1 0.1 2.2 2 0 0 2 2 2 0 Snapin/Pallidin HR1 PF02185.11 CAM70097.1 - 3.3 7.5 6.6 0.99 9.1 1.8 1.9 2 0 0 2 2 2 0 Hr1 repeat DUF4115 PF13464.1 CAM70099.1 - 0.083 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4115) PAT1 PF09770.4 CAM70099.1 - 2.7 6.1 7.9 3.2 5.8 5.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Mannosyl_trans PF05007.8 CAM70100.1 - 1.3e-83 280.6 12.8 1.8e-83 280.1 8.9 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) DUF2029 PF09594.5 CAM70100.1 - 3.4e-10 39.8 13.1 3.4e-10 39.8 9.1 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF2029) PIG-U PF06728.8 CAM70100.1 - 9.6e-10 37.8 16.3 3.3e-09 36.0 11.0 1.9 1 1 1 2 2 2 1 GPI transamidase subunit PIG-U Peptidase_C2 PF00648.16 CAM70101.1 - 3.3e-26 91.9 0.1 6.8e-12 44.9 0.0 4.2 4 0 0 4 4 4 3 Calpain family cysteine protease Calpain_III PF01067.17 CAM70101.1 - 1.7e-09 37.4 0.0 4.9e-05 23.0 0.0 2.8 3 0 0 3 3 3 2 Calpain large subunit, domain III LRR_6 PF13516.1 CAM70101.1 - 0.00045 19.9 5.4 1.9 8.8 0.1 3.7 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.28 CAM70101.1 - 0.14 12.3 8.3 19 5.7 1.1 3.9 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_7 PF13504.1 CAM70101.1 - 0.46 10.9 3.6 37 5.1 0.2 3.6 3 0 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.2 CAM70101.1 - 0.67 9.6 10.8 8.7 6.0 6.3 2.6 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) Cytochrom_B561 PF03188.11 CAM70102.1 - 9.7e-11 41.6 7.4 5.3e-10 39.2 5.1 2.0 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 zf-C3HC4_4 PF15227.1 CAM70104.2 - 0.0023 17.7 10.2 0.0023 17.7 7.0 2.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 CAM70104.2 - 0.011 15.7 10.0 0.011 15.7 6.9 2.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) YjbE PF11106.3 CAM70105.1 - 0.079 12.9 2.4 0.15 12.0 1.7 1.4 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE DUF814 PF05670.8 CAM70106.1 - 5.4e-22 77.4 0.0 8.8e-22 76.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Atg14 PF10186.4 CAM70106.1 - 4 6.3 8.2 5.5 5.8 5.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1764 PF08576.5 CAM70106.1 - 4.7 8.0 9.8 7.1 7.4 6.8 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF3987 PF13148.1 CAM70106.1 - 5.1 5.5 8.9 6.3 5.2 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AAA_16 PF13191.1 CAM70107.2 - 0.0025 17.8 0.1 0.0058 16.6 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 CAM70107.2 - 0.0085 15.8 0.6 0.036 13.8 0.2 2.2 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 CAM70107.2 - 0.0098 15.5 0.0 0.022 14.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 CAM70107.2 - 0.012 15.7 0.0 0.052 13.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 CAM70107.2 - 0.028 14.0 0.0 0.25 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CAM70107.2 - 0.032 13.6 0.2 0.092 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 CAM70107.2 - 0.044 13.2 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF87 PF01935.12 CAM70107.2 - 0.12 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_10 PF12846.2 CAM70107.2 - 0.12 11.8 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Fe-ADH PF00465.14 CAM70108.1 - 5.9e-108 360.7 1.1 6.6e-108 360.6 0.8 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 CAM70108.1 - 8.2e-21 74.4 0.1 1.7e-13 50.4 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase DUF1664 PF07889.7 CAM70109.1 - 0.0011 18.7 1.1 0.0029 17.4 0.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) DUF148 PF02520.12 CAM70109.1 - 0.0022 17.7 5.4 0.0039 16.9 3.7 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF148 OmpH PF03938.9 CAM70109.1 - 0.016 15.1 2.1 0.035 14.0 1.5 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Baculo_PEP_C PF04513.7 CAM70109.1 - 0.036 13.8 1.0 0.07 12.9 0.7 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Flagellin_N PF00669.15 CAM70109.1 - 0.047 13.4 4.1 0.14 11.9 2.8 1.8 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region FlgN PF05130.7 CAM70109.1 - 0.056 13.6 6.6 0.055 13.7 2.9 2.2 2 0 0 2 2 2 0 FlgN protein Apolipoprotein PF01442.13 CAM70109.1 - 0.092 12.2 4.9 0.055 12.9 1.9 1.8 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Salp15 PF12115.3 CAM70109.1 - 0.1 12.7 0.3 0.23 11.7 0.2 1.6 1 0 0 1 1 1 0 Salivary protein of 15kDa inhibits CD4+ T cell activation Syntaxin PF00804.20 CAM70109.1 - 0.12 12.5 2.3 0.29 11.3 1.6 1.7 1 0 0 1 1 1 0 Syntaxin Med15_fungi PF05397.7 CAM70109.1 - 0.16 11.9 1.5 0.32 10.9 1.0 1.5 1 0 0 1 1 1 0 Mediator complex subunit 15 HisKA_3 PF07730.8 CAM70109.1 - 0.18 12.2 3.7 0.31 11.4 1.3 2.6 2 0 0 2 2 1 0 Histidine kinase ARL2_Bind_BART PF11527.3 CAM70109.1 - 0.25 11.1 1.8 0.49 10.1 1.3 1.4 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART DUF883 PF05957.8 CAM70109.1 - 0.31 11.4 6.2 0.12 12.7 1.6 2.4 2 1 0 2 2 1 0 Bacterial protein of unknown function (DUF883) Oligomerisation PF02410.10 CAM70111.1 - 1.3e-14 54.0 0.9 2e-14 53.4 0.6 1.3 1 0 0 1 1 1 1 Oligomerisation domain Pkinase PF00069.20 CAM70112.1 - 6e-51 173.0 0.0 7.6e-38 130.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAM70112.1 - 3.2e-35 121.4 0.0 6.4e-28 97.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Beta_helix PF13229.1 CAM70112.1 - 7.9e-29 100.4 16.3 1.1e-16 61.0 2.0 3.3 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.8 CAM70112.1 - 4.8e-25 88.1 0.2 2.2e-15 56.4 0.4 2.2 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) Kinase-like PF14531.1 CAM70112.1 - 1.1e-06 27.8 0.1 4.6e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like DUF1565 PF07602.6 CAM70112.1 - 0.00027 20.1 5.7 0.019 14.0 4.0 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1565) zf-B_box PF00643.19 CAM70112.1 - 0.0063 16.3 8.1 0.019 14.8 5.6 1.8 1 0 0 1 1 1 1 B-box zinc finger APH PF01636.18 CAM70112.1 - 0.031 14.0 0.1 0.41 10.3 0.0 2.6 3 1 0 3 3 3 0 Phosphotransferase enzyme family Patatin PF01734.17 CAM70113.1 - 1.3e-23 84.0 0.0 1.3e-23 84.0 0.0 2.8 3 1 1 4 4 4 1 Patatin-like phospholipase DUF3336 PF11815.3 CAM70113.1 - 6.9e-17 61.3 0.0 1.2e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) WD40 PF00400.27 CAM70114.1 - 1e-14 53.7 10.2 0.034 14.0 0.0 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat IBR PF01485.16 CAM70116.1 - 2.1e-14 53.1 50.4 1.7e-09 37.4 9.5 4.5 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 CAM70116.1 - 0.00049 19.8 12.8 0.00049 19.8 8.9 4.0 3 1 1 4 4 4 2 Ring finger domain UBA_4 PF14555.1 CAM70116.1 - 0.026 14.0 0.0 0.064 12.8 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain Chor_lyase PF04345.8 CAM70116.1 - 0.069 12.5 0.1 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Chorismate lyase zf-C3HC4 PF00097.20 CAM70116.1 - 1.3 8.7 40.8 0.056 13.0 7.5 4.0 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAM70116.1 - 6.4 6.5 45.5 0.02 14.6 8.8 4.3 2 1 1 3 3 3 0 zinc-RING finger domain RRM_1 PF00076.17 CAM70117.1 - 1.6e-25 88.5 0.0 2.3e-14 52.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM70117.1 - 5.4e-16 58.3 0.0 1.4e-08 34.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM70117.1 - 8.8e-07 28.6 0.1 0.02 14.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TIR-like PF10137.4 CAM70117.1 - 0.13 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain RRM_1 PF00076.17 CAM70118.1 - 1e-23 82.7 2.2 8.1e-15 54.2 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM70118.1 - 4.8e-18 64.8 0.0 1.5e-09 37.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM70118.1 - 5.6e-07 29.3 0.1 0.00071 19.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mito_fiss_reg PF05308.6 CAM70118.1 - 6.4 6.0 6.1 12 5.2 4.2 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator zf-CCCH PF00642.19 CAM70119.1 - 4.7e-08 32.5 0.5 6.6e-08 32.0 0.4 1.2 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CAM70119.1 - 0.021 14.8 1.0 0.042 13.8 0.7 1.5 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type DUF155 PF02582.9 CAM70121.1 - 1.7e-19 70.4 0.0 3.3e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Alkyl_sulf_dimr PF14863.1 CAM70121.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation Mito_carr PF00153.22 CAM70123.1 - 1.3e-11 43.9 9.5 0.0027 17.3 0.1 4.9 5 1 0 5 5 5 4 Mitochondrial carrier protein Polysacc_synt_C PF14667.1 CAM70123.1 - 0.078 12.7 0.3 1.5 8.5 0.1 2.7 3 0 0 3 3 3 0 Polysaccharide biosynthesis C-terminal domain zf-C2H2_2 PF12756.2 CAM70124.1 - 1.4e-24 86.1 7.6 1.4e-18 66.8 0.9 3.1 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 CAM70124.1 - 5.4e-09 35.9 7.5 3.1e-06 27.1 0.6 3.9 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CAM70124.1 - 9.3e-09 34.9 5.2 0.0019 18.0 1.0 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 CAM70124.1 - 3.5e-05 23.8 15.3 0.00082 19.4 1.8 4.1 4 1 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 CAM70124.1 - 0.0021 18.2 13.9 0.12 12.7 1.2 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CAM70124.1 - 0.0052 17.0 16.0 0.027 14.7 1.7 4.0 4 0 0 4 4 4 2 Zinc finger, C2H2 type C1_1 PF00130.17 CAM70124.1 - 0.96 9.2 0.0 0.96 9.2 0.0 3.2 3 1 1 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-FCS PF06467.9 CAM70124.1 - 4.5 6.9 6.6 0.69 9.6 0.2 2.8 4 0 0 4 4 4 0 MYM-type Zinc finger with FCS sequence motif AKAP95 PF04988.7 CAM70124.1 - 4.5 7.0 8.5 39 3.9 2.7 3.4 3 1 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) Hydrolase PF00702.21 CAM70125.1 - 1.3e-12 48.6 0.3 3.4e-07 30.8 0.2 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CAM70125.1 - 2.1e-12 46.6 0.0 3.7e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 CAM70125.1 - 3.4e-09 37.1 0.0 3.5e-08 33.8 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CAM70125.1 - 1.3e-07 31.4 0.0 3.6e-07 30.0 0.0 1.8 1 1 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CAM70125.1 - 0.0073 15.9 0.1 0.015 14.9 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase LRR_4 PF12799.2 CAM70126.1 - 3.7e-20 71.1 8.8 5.7e-07 29.0 0.1 6.8 4 2 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM70126.1 - 4.8e-11 42.2 14.8 9e-06 25.3 0.2 5.6 4 2 4 8 8 8 6 Leucine rich repeat LRR_1 PF00560.28 CAM70126.1 - 1.1e-05 24.7 14.4 12 6.4 0.2 8.5 8 1 0 8 8 8 3 Leucine Rich Repeat LRR_7 PF13504.1 CAM70126.1 - 0.0006 19.5 27.5 2.8 8.5 0.3 10.0 11 1 0 11 11 11 1 Leucine rich repeat LRR_6 PF13516.1 CAM70126.1 - 0.0088 16.0 11.5 11 6.4 0.0 7.7 9 1 0 9 9 9 1 Leucine Rich repeat TTL PF03133.10 CAM70127.1 - 1.1e-48 165.6 0.0 7.4e-30 103.8 0.0 3.1 3 0 0 3 3 3 3 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 CAM70127.1 - 8.9e-05 21.4 0.0 0.3 9.8 0.0 2.4 2 0 0 2 2 2 2 YheC/D like ATP-grasp CP_ATPgrasp_1 PF04174.8 CAM70127.1 - 0.078 11.5 0.0 0.17 10.4 0.0 1.5 1 0 0 1 1 1 0 A circularly permuted ATPgrasp Dala_Dala_lig_C PF07478.8 CAM70127.1 - 0.12 11.7 0.1 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Helicase_C PF00271.26 CAM70128.1 - 4.6e-15 55.2 0.1 9.2e-15 54.2 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAM70128.1 - 1.7e-13 50.4 0.0 2e-12 46.9 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase MRF_C1 PF13887.1 CAM70128.1 - 0.089 11.8 0.0 0.2 10.6 0.0 1.6 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 Drf_FH3 PF06367.11 CAM70129.1 - 0.04 13.3 4.1 0.064 12.6 2.8 1.3 1 0 0 1 1 1 0 Diaphanous FH3 Domain SET PF00856.23 CAM70131.1 - 3.9e-06 27.2 0.0 5.4e-05 23.5 0.0 2.1 2 1 0 2 2 2 1 SET domain Pyridoxal_deC PF00282.14 CAM70134.1 - 3.6e-19 68.4 0.0 8.6e-19 67.2 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 CAM70134.1 - 2.3e-11 43.0 0.0 6.8e-11 41.5 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 CAM70134.1 - 0.051 12.6 0.0 0.083 11.9 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family zf-C3HC4 PF00097.20 CAM70135.1 - 1.3e-08 34.3 6.2 1.3e-08 34.3 4.3 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CAM70135.1 - 3.2e-08 33.2 7.8 3.2e-08 33.2 5.4 3.9 3 1 1 4 4 4 1 zinc finger of C3HC4-type, RING zf-B_box PF00643.19 CAM70135.1 - 6.3e-08 32.3 40.8 3.7e-07 29.9 5.1 4.3 4 0 0 4 4 4 2 B-box zinc finger zf-C3HC4_2 PF13923.1 CAM70135.1 - 1.5e-05 24.9 7.3 1.5e-05 24.9 5.0 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAM70135.1 - 7.8e-05 22.3 8.1 7.8e-05 22.3 5.6 3.6 2 1 0 2 2 2 1 zinc-RING finger domain Spc7 PF08317.6 CAM70135.1 - 0.011 14.4 0.4 0.015 13.9 0.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein SpaB_C PF14028.1 CAM70135.1 - 0.064 12.8 1.2 0.11 12.0 0.8 1.3 1 0 0 1 1 1 0 SpaB C-terminal domain Flg_hook PF02120.11 CAM70135.1 - 0.52 10.0 4.0 0.2 11.3 0.5 2.0 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK Arf PF00025.16 CAM70136.1 - 1.7e-49 167.4 0.0 1.9e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CAM70136.1 - 8.2e-18 64.2 0.0 1.1e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CAM70136.1 - 2.8e-11 43.0 0.0 3.4e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAM70136.1 - 8.1e-11 42.4 0.0 1e-10 42.1 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CAM70136.1 - 1.2e-10 41.3 0.0 1.6e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 CAM70136.1 - 2.1e-09 36.5 0.0 3.2e-06 26.1 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CAM70136.1 - 1.4e-06 27.6 0.0 2e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CAM70136.1 - 4.8e-05 22.8 0.0 0.00031 20.2 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CAM70136.1 - 0.00017 20.8 0.0 0.00034 19.9 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B CdhD PF03599.11 CAM70136.1 - 0.017 13.6 0.0 0.023 13.1 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit cobW PF02492.14 CAM70136.1 - 0.027 13.8 0.1 1.7 8.0 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 CAM70136.1 - 0.032 13.9 0.0 0.032 13.9 0.0 1.4 1 1 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 CAM70136.1 - 0.1 12.4 0.0 0.42 10.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF3373 PF11853.3 CAM70137.1 - 0.41 9.1 7.8 0.052 12.0 2.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) XdhC_C PF13478.1 CAM70137.1 - 0.69 10.2 8.8 1.2 9.4 4.4 2.7 1 1 1 2 2 2 0 XdhC Rossmann domain MMR_HSR1_C PF08438.5 CAM70137.1 - 1.1 9.4 9.8 0.9 9.7 0.9 2.6 1 1 1 2 2 2 0 GTPase of unknown function C-terminal Reo_sigmaC PF04582.7 CAM70137.1 - 9.4 5.3 10.9 0.87 8.7 1.7 2.6 1 1 3 4 4 4 0 Reovirus sigma C capsid protein Hemopexin PF00045.14 CAM70138.2 - 0.096 12.4 0.8 1.6 8.5 0.0 3.2 3 0 0 3 3 3 0 Hemopexin OpgC_C PF10129.4 CAM70139.1 - 0.012 14.3 1.8 0.016 13.9 1.3 1.1 1 0 0 1 1 1 0 OpgC protein Clp1 PF06807.9 CAM70140.1 - 6.9e-14 52.0 0.0 2.8e-13 50.0 0.0 2.0 2 1 0 2 2 2 1 Pre-mRNA cleavage complex II protein Clp1 PTH2 PF01981.11 CAM70141.1 - 1.1e-11 44.4 0.6 2.3e-11 43.4 0.4 1.5 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 PilM PF07419.7 CAM70141.1 - 0.033 13.6 0.1 0.063 12.7 0.1 1.4 1 0 0 1 1 1 0 PilM Hydrolase PF00702.21 CAM70141.1 - 0.046 14.1 0.1 0.054 13.8 0.0 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Beta_elim_lyase PF01212.16 CAM70141.1 - 0.13 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Peptidase_C4 PF00863.14 CAM70141.1 - 0.14 11.0 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C4 TPR_11 PF13414.1 CAM70143.1 - 8.7e-06 25.2 0.0 0.00043 19.8 0.0 2.4 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 CAM70143.1 - 0.0014 18.3 0.1 0.74 9.8 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CAM70143.1 - 0.15 11.8 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2256 PF10013.4 CAM70143.1 - 1.5 8.6 3.8 3.2 7.5 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) DnaJ PF00226.26 CAM70144.1 - 5.1e-14 51.7 0.0 1.3e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Plasmodium_Vir PF05795.6 CAM70144.1 - 0.00028 20.2 0.1 0.00036 19.8 0.0 1.1 1 0 0 1 1 1 1 Plasmodium vivax Vir protein HSP70 PF00012.15 CAM70145.1 - 6.7e-247 820.2 6.1 7.8e-247 820.0 4.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CAM70145.1 - 3.5e-14 52.1 0.6 7.4e-13 47.7 0.1 2.5 2 1 0 2 2 2 1 MreB/Mbl protein PIN_3 PF13470.1 CAM70145.1 - 0.022 15.4 0.7 0.41 11.3 0.0 2.4 2 0 0 2 2 2 0 PIN domain Dynamin_M PF01031.15 CAM70145.1 - 0.053 12.2 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 Dynamin central region Taeniidae_ag PF05596.6 CAM70145.1 - 0.083 12.7 0.7 0.31 10.8 0.5 1.9 1 0 0 1 1 1 0 Taeniidae antigen FtsA PF14450.1 CAM70145.1 - 0.088 12.6 12.0 0.69 9.7 0.0 4.9 4 1 0 4 4 4 0 Cell division protein FtsA StbA PF06406.6 CAM70145.1 - 0.11 11.4 7.6 0.73 8.7 0.0 3.9 4 1 1 5 5 5 0 StbA protein Hydantoinase_A PF01968.13 CAM70145.1 - 0.51 9.3 9.8 2 7.4 0.2 3.7 4 0 0 4 4 4 0 Hydantoinase/oxoprolinase DUF4404 PF14357.1 CAM70145.1 - 0.64 10.4 3.0 0.63 10.5 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) HSP70 PF00012.15 CAM70146.1 - 8.8e-260 862.7 9.2 1e-259 862.5 6.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CAM70146.1 - 2.8e-14 52.4 0.8 5.6e-13 48.1 0.2 2.6 2 1 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 CAM70146.1 - 0.013 15.2 13.1 0.7 9.7 0.0 4.9 4 1 0 4 4 4 0 Cell division protein FtsA PIN_3 PF13470.1 CAM70146.1 - 0.023 15.3 0.6 0.43 11.2 0.0 2.4 2 0 0 2 2 2 0 PIN domain Taeniidae_ag PF05596.6 CAM70146.1 - 0.076 12.8 0.7 0.32 10.8 0.5 2.0 1 0 0 1 1 1 0 Taeniidae antigen Hydantoinase_A PF01968.13 CAM70146.1 - 0.48 9.4 10.7 2.1 7.3 0.2 3.7 4 0 0 4 4 4 0 Hydantoinase/oxoprolinase PQQ_3 PF13570.1 CAM70148.1 - 0.018 15.3 1.8 7.1 7.0 0.0 4.1 3 1 1 4 4 4 0 PQQ-like domain Oleosin PF01277.12 CAM70149.1 - 0.19 11.2 0.2 0.19 11.2 0.1 1.6 2 0 0 2 2 2 0 Oleosin AAA PF00004.24 CAM70150.1 - 1.3e-46 158.0 0.0 1.7e-40 138.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CAM70150.1 - 1.7e-05 24.9 0.0 0.27 11.3 0.0 3.0 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.1 CAM70150.1 - 0.00016 21.7 6.3 0.38 10.7 0.0 4.5 2 2 2 4 4 4 1 AAA ATPase domain RuvB_N PF05496.7 CAM70150.1 - 0.00038 19.5 0.0 0.0014 17.7 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 CAM70150.1 - 0.00098 18.5 0.1 0.15 11.4 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_5 PF07728.9 CAM70150.1 - 0.0024 17.6 0.0 0.068 12.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Vps4_C PF09336.5 CAM70150.1 - 0.0037 17.1 0.0 0.014 15.2 0.0 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain TIP49 PF06068.8 CAM70150.1 - 0.0053 15.5 0.0 0.0098 14.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 CAM70150.1 - 0.011 15.1 3.0 2 7.7 0.0 3.8 2 2 0 3 3 3 0 AAA domain AAA_33 PF13671.1 CAM70150.1 - 0.021 14.6 0.1 1.2 9.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_2 PF07724.9 CAM70150.1 - 0.025 14.5 0.0 0.058 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) NACHT PF05729.7 CAM70150.1 - 0.027 14.1 0.1 4.6 6.8 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Mg_chelatase PF01078.16 CAM70150.1 - 0.031 13.4 0.0 0.08 12.1 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 CAM70150.1 - 0.039 13.0 0.0 0.15 11.0 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.17 CAM70150.1 - 0.067 13.3 0.0 0.47 10.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Sigma54_activ_2 PF14532.1 CAM70150.1 - 0.091 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.1 CAM70150.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 CAM70150.1 - 0.26 10.8 0.0 5 6.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 CAM70150.1 - 0.26 9.9 0.0 0.4 9.3 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 CAM70150.1 - 0.38 10.4 0.0 19 4.8 0.0 2.5 2 1 1 3 3 3 0 Archaeal ATPase HSP70 PF00012.15 CAM70151.1 - 1.3e-259 862.2 9.1 1.5e-259 862.0 6.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CAM70151.1 - 3.4e-14 52.1 0.7 7.1e-13 47.8 0.1 2.6 2 1 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 CAM70151.1 - 0.013 15.3 12.9 0.73 9.6 0.0 4.9 4 1 0 4 4 4 0 Cell division protein FtsA PIN_3 PF13470.1 CAM70151.1 - 0.022 15.3 0.5 0.43 11.2 0.0 2.4 2 0 0 2 2 2 0 PIN domain Taeniidae_ag PF05596.6 CAM70151.1 - 0.076 12.8 0.7 0.32 10.8 0.5 2.0 1 0 0 1 1 1 0 Taeniidae antigen Hydantoinase_A PF01968.13 CAM70151.1 - 0.42 9.6 10.3 2.1 7.3 0.2 3.7 4 0 0 4 4 4 0 Hydantoinase/oxoprolinase HSP70 PF00012.15 CAM70152.1 - 8e-260 862.9 9.2 9.6e-260 862.6 6.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CAM70152.1 - 3.4e-14 52.1 0.8 6.7e-13 47.9 0.2 2.6 2 1 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 CAM70152.1 - 0.014 15.2 13.0 0.72 9.7 0.0 4.9 4 1 0 4 4 4 0 Cell division protein FtsA PIN_3 PF13470.1 CAM70152.1 - 0.022 15.3 0.5 0.43 11.2 0.0 2.4 2 0 0 2 2 2 0 PIN domain Taeniidae_ag PF05596.6 CAM70152.1 - 0.076 12.8 0.7 0.32 10.8 0.5 2.0 1 0 0 1 1 1 0 Taeniidae antigen Hydantoinase_A PF01968.13 CAM70152.1 - 0.58 9.2 11.0 2.1 7.3 0.2 3.7 4 0 0 4 4 4 0 Hydantoinase/oxoprolinase Cofilin_ADF PF00241.15 CAM70154.1 - 0.00019 21.3 0.0 0.0074 16.1 0.0 2.3 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein RecT PF03837.9 CAM70154.1 - 0.04 13.2 0.0 0.082 12.1 0.0 1.5 1 0 0 1 1 1 0 RecT family MCPVI PF02993.9 CAM70154.1 - 1.2 9.1 6.4 0.15 12.1 0.8 2.0 2 1 0 2 2 2 0 Minor capsid protein VI Reticulon PF02453.12 CAM70155.1 - 2.3e-36 124.9 7.0 2.9e-36 124.6 4.8 1.1 1 0 0 1 1 1 1 Reticulon PrgI PF12666.2 CAM70155.1 - 0.046 13.8 9.9 0.11 12.6 1.0 2.5 1 1 1 2 2 2 0 PrgI family protein Cytomega_TRL10 PF06084.6 CAM70155.1 - 0.12 12.1 0.7 0.3 10.8 0.5 1.7 1 1 0 1 1 1 0 Cytomegalovirus TRL10 protein PRT_C PF08372.5 CAM70155.1 - 0.15 11.5 3.4 0.74 9.3 0.2 2.2 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal DUF883 PF05957.8 CAM70155.1 - 0.25 11.7 2.1 0.9 9.9 1.1 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF3292 PF11696.3 CAM70155.1 - 1.2 6.9 5.6 0.055 11.3 0.2 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3292) IncA PF04156.9 CAM70155.1 - 1.3 8.6 4.0 13 5.3 0.4 2.1 2 0 0 2 2 2 0 IncA protein Leu_Phe_trans PF03588.9 CAM70156.1 - 0.0015 17.7 0.4 0.021 13.9 0.1 2.4 2 1 0 2 2 2 1 Leucyl/phenylalanyl-tRNA protein transferase FTHFS PF01268.14 CAM70157.1 - 2.3e-259 861.0 0.0 2.6e-259 860.8 0.0 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase Lipase_GDSL_2 PF13472.1 CAM70157.1 - 0.09 12.9 0.0 0.32 11.0 0.0 1.9 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family RRM_1 PF00076.17 CAM70158.1 - 6.8e-16 57.6 0.0 1.4e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM70158.1 - 2.8e-14 52.8 0.0 4.7e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM70158.1 - 9.3e-08 31.8 0.3 1.7e-07 30.9 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CAM70158.1 - 0.0071 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif AAA PF00004.24 CAM70161.1 - 1.4e-13 51.1 0.0 2.8e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 CAM70161.1 - 4.4e-10 39.3 0.0 8.4e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 CAM70161.1 - 1.4e-08 34.5 0.0 2.1e-07 30.7 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.1 CAM70161.1 - 6.6e-06 26.3 0.0 6.2e-05 23.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CAM70161.1 - 1.1e-05 24.5 0.0 3.3e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 CAM70161.1 - 1.4e-05 24.8 0.0 6.1e-05 22.7 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 CAM70161.1 - 1.4e-05 25.1 1.4 0.0012 18.9 0.0 3.0 1 1 1 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 CAM70161.1 - 5e-05 22.9 0.0 0.00016 21.3 0.0 1.9 2 0 0 2 2 1 1 Part of AAA domain Rad17 PF03215.10 CAM70161.1 - 7.4e-05 21.6 0.0 0.00065 18.5 0.0 2.0 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein DUF2075 PF09848.4 CAM70161.1 - 0.00037 19.5 0.0 0.00051 19.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 CAM70161.1 - 0.005 16.6 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_33 PF13671.1 CAM70161.1 - 0.0056 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CAM70161.1 - 0.011 15.6 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 CAM70161.1 - 0.018 14.6 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CAM70161.1 - 0.021 14.5 0.0 0.049 13.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 CAM70161.1 - 0.026 14.5 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 CAM70161.1 - 0.031 13.4 0.2 0.075 12.1 0.1 1.8 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 CAM70161.1 - 0.033 13.6 0.2 0.55 9.6 0.0 2.4 1 1 1 2 2 2 0 AAA domain DEAD PF00270.24 CAM70161.1 - 0.049 13.1 0.0 0.86 9.0 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF815 PF05673.8 CAM70161.1 - 0.051 12.4 0.0 0.087 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Viral_helicase1 PF01443.13 CAM70161.1 - 0.074 12.5 0.0 0.17 11.3 0.0 1.7 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.1 CAM70161.1 - 0.13 12.5 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 CAM70161.1 - 0.15 11.6 0.0 0.76 9.3 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CLASP_N PF12348.3 CAM70162.1 - 0.0014 18.0 0.0 0.0056 16.0 0.0 1.9 3 0 0 3 3 3 1 CLASP N terminal DUF3136 PF11334.3 CAM70162.1 - 0.084 12.3 0.6 9 5.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3136) ubiquitin PF00240.18 CAM70164.1 - 0.00088 18.6 0.0 0.0017 17.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family IL10 PF00726.12 CAM70164.1 - 0.13 11.5 0.1 0.21 10.8 0.1 1.2 1 0 0 1 1 1 0 Interleukin 10 TPR_12 PF13424.1 CAM70165.1 - 1.8e-05 24.6 2.6 0.001 18.9 0.0 3.3 3 1 0 4 4 4 1 Tetratricopeptide repeat DUF3156 PF11354.3 CAM70165.1 - 0.013 14.8 0.1 0.037 13.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3156) TPR_11 PF13414.1 CAM70165.1 - 0.032 13.8 3.2 0.14 11.7 0.2 3.1 3 1 1 4 4 4 0 TPR repeat TPR_10 PF13374.1 CAM70165.1 - 0.16 11.9 6.3 2.6 8.0 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPT PF03151.11 CAM70167.1 - 4.5e-19 68.6 10.2 4.5e-19 68.6 7.1 2.9 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 CAM70167.1 - 0.00037 19.5 21.1 0.00067 18.6 14.7 1.4 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.1 CAM70167.1 - 0.0065 16.6 20.5 0.017 15.3 3.1 3.7 2 1 1 3 3 3 2 Multidrug resistance efflux transporter EamA PF00892.15 CAM70167.1 - 0.34 10.9 31.7 0.024 14.6 8.5 3.6 1 1 2 3 3 3 0 EamA-like transporter family SH3_9 PF14604.1 CAM70168.1 - 5.9e-07 28.9 0.0 9e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CAM70168.1 - 2.7e-06 26.7 0.0 4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CAM70168.1 - 0.00016 20.9 0.0 0.00031 20.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain DUF4648 PF15505.1 CAM70168.1 - 0.083 13.0 0.8 0.25 11.5 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4648) Tmemb_cc2 PF10267.4 CAM70168.1 - 0.096 11.2 0.1 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein SOG2 PF10428.4 CAM70168.1 - 0.27 9.8 3.0 0.37 9.3 2.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein LRR_6 PF13516.1 CAM70169.1 - 0.015 15.2 0.0 4.4 7.6 0.0 2.8 2 0 0 2 2 2 0 Leucine Rich repeat GRAM PF02893.15 CAM70171.1 - 6.9e-09 35.1 0.0 1.5e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 GRAM domain SPA PF08616.5 CAM70172.1 - 9.3e-29 99.4 0.0 2.6e-28 97.9 0.0 1.8 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.7 CAM70172.1 - 1.1e-07 31.9 0.0 9.5e-06 25.6 0.0 2.3 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.4 CAM70172.1 - 0.00064 18.3 0.0 0.08 11.4 0.0 2.4 1 1 1 2 2 2 2 Transport protein Avl9 DUF2347 PF09804.4 CAM70172.1 - 0.003 16.8 0.0 0.0067 15.7 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DENN PF02141.16 CAM70172.1 - 0.0074 16.0 1.2 0.01 15.5 0.1 1.9 2 1 0 2 2 2 1 DENN (AEX-3) domain TPR_11 PF13414.1 CAM70173.1 - 1.1e-27 95.4 6.3 1.8e-19 69.1 1.6 2.8 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 CAM70173.1 - 1.8e-26 90.6 8.4 1.5e-08 33.9 0.7 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 CAM70173.1 - 3e-19 67.3 13.8 3.2e-07 29.7 0.0 4.9 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 CAM70173.1 - 1.3e-11 43.7 4.2 0.00052 20.0 0.2 4.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CAM70173.1 - 1.2e-10 41.1 5.3 9e-07 28.7 0.2 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 CAM70173.1 - 1.4e-09 38.3 8.6 3.3e-07 30.7 0.1 3.5 3 1 0 4 4 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CAM70173.1 - 4.1e-09 36.2 1.9 0.019 15.5 0.0 4.7 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 CAM70173.1 - 1.6e-08 33.7 1.9 0.0082 15.8 0.0 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CAM70173.1 - 2.9e-08 32.9 4.7 0.0069 16.0 0.8 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CAM70173.1 - 1.2e-06 28.7 4.2 0.001 19.3 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat SGT1 PF07093.6 CAM70173.1 - 1.2e-05 23.9 0.3 2.1e-05 23.1 0.2 1.4 1 0 0 1 1 1 1 SGT1 protein TPR_9 PF13371.1 CAM70173.1 - 4.8e-05 23.1 0.1 0.018 14.8 0.0 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 CAM70173.1 - 0.00013 21.9 5.5 0.01 15.9 3.9 2.8 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CAM70173.1 - 0.0021 18.3 4.7 1.2 9.7 0.0 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TOM20_plant PF06552.7 CAM70173.1 - 0.01 15.4 1.3 0.33 10.5 0.2 2.9 1 1 1 2 2 2 1 Plant specific mitochondrial import receptor subunit TOM20 Fis1_TPR_C PF14853.1 CAM70173.1 - 0.016 15.1 2.7 13 5.7 0.0 3.4 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.13 CAM70173.1 - 0.035 13.9 4.1 0.44 10.4 0.4 3.1 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Ins_allergen_rp PF06757.8 CAM70173.1 - 0.11 11.9 0.4 2.5 7.5 0.0 2.6 3 0 0 3 3 3 0 Insect allergen related repeat, nitrile-specifier detoxification DSBA PF01323.15 CAM70174.1 - 0.037 13.5 0.4 0.058 12.9 0.3 1.3 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Methyltransf_5 PF01795.14 CAM70174.1 - 0.04 13.1 0.3 0.057 12.6 0.2 1.2 1 0 0 1 1 1 0 MraW methylase family TMA7 PF09072.5 CAM70175.1 - 6.3e-20 71.4 13.0 6.8e-20 71.3 9.0 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 TLE_N PF03920.10 CAM70175.1 - 0.12 12.2 2.1 0.11 12.2 1.5 1.0 1 0 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain FixG_C PF11614.3 CAM70176.1 - 0.0048 16.9 0.4 0.0064 16.5 0.3 1.4 1 1 0 1 1 1 1 IG-like fold at C-terminal of FixG, putative oxidoreductase Sod_Fe_N PF00081.17 CAM70177.1 - 2.4e-06 27.6 0.1 3.8e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.13 CAM70177.1 - 5.3e-06 26.2 0.0 1.2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain CATSPERG PF15064.1 CAM70177.1 - 0.026 12.2 0.0 0.039 11.6 0.0 1.2 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit gamma zf-CCCH PF00642.19 CAM70178.1 - 1.8e-06 27.4 2.4 1.8e-06 27.4 1.7 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CAM70178.1 - 0.052 13.5 1.7 0.13 12.3 1.2 1.7 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type DUF872 PF05915.7 CAM70179.1 - 3.5e-07 30.0 1.3 5e-07 29.5 0.9 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) DUF3592 PF12158.3 CAM70179.1 - 5.2 6.8 5.6 0.39 10.5 0.4 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3592) Vac14_Fig4_bd PF11916.3 CAM70180.1 - 0.14 11.2 0.4 0.87 8.7 0.0 2.0 2 0 0 2 2 2 0 Vacuolar protein 14 C-terminal Fig4p binding Cpn60_TCP1 PF00118.19 CAM70182.1 - 1.5e-110 370.1 0.4 1.7e-110 369.9 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RabGAP-TBC PF00566.13 CAM70184.1 - 2.8e-34 118.4 0.6 9.4e-34 116.7 0.4 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain GAT PF03127.9 CAM70188.1 - 0.06 13.3 0.0 0.34 10.8 0.0 2.2 2 0 0 2 2 2 0 GAT domain PPR_3 PF13812.1 CAM70189.1 - 1.6e-07 31.0 7.7 0.28 11.5 0.0 6.9 6 0 0 6 6 6 3 Pentatricopeptide repeat domain PPR_2 PF13041.1 CAM70189.1 - 4.8e-05 23.2 0.0 12 5.9 0.0 5.3 5 0 0 5 5 5 1 PPR repeat family Apc3 PF12895.2 CAM70189.1 - 0.0001 22.3 1.2 2.7 8.2 0.0 4.3 4 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 CAM70189.1 - 0.00024 20.8 0.8 48 4.2 0.0 5.9 7 0 0 7 7 7 0 PPR repeat TPR_7 PF13176.1 CAM70189.1 - 0.0065 16.1 6.6 1e+02 3.1 0.0 6.9 9 0 0 9 9 9 0 Tetratricopeptide repeat Aldedh PF00171.17 CAM70191.1 - 1.3e-118 396.3 0.0 1.7e-118 395.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pkinase PF00069.20 CAM70192.1 - 1.8e-53 181.3 0.0 2.2e-53 181.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM70192.1 - 4.2e-18 65.3 0.0 5.8e-18 64.8 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CAM70192.1 - 5.8e-06 25.5 0.0 9.2e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CAM70192.1 - 0.00033 20.4 0.2 0.00048 19.9 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CAM70192.1 - 0.0028 16.6 0.0 0.0088 15.0 0.0 1.8 2 1 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.4 CAM70192.1 - 0.05 12.9 0.1 0.11 11.8 0.0 1.5 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL PI-PLC-X PF00388.14 CAM70196.2 - 2.5e-58 195.6 0.0 5e-58 194.6 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 CAM70196.2 - 6.2e-34 116.5 0.0 1e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 CAM70196.2 - 1e-16 60.5 0.3 5.5e-16 58.1 0.1 2.4 2 0 0 2 2 2 1 C2 domain EF-hand_7 PF13499.1 CAM70196.2 - 9.5e-11 41.6 0.2 5.1e-07 29.7 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CAM70196.2 - 1.5e-08 33.3 0.0 0.0045 16.1 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 CAM70196.2 - 3.7e-07 29.6 5.4 3.3e-05 23.4 0.2 3.2 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 CAM70196.2 - 9.3e-07 27.9 0.7 0.0069 15.6 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CAM70196.2 - 1.4e-06 27.6 0.1 0.18 11.7 0.1 3.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_10 PF14788.1 CAM70196.2 - 3.8e-06 26.4 0.1 7.7e-06 25.4 0.1 1.6 1 0 0 1 1 1 1 EF hand GDPD PF03009.12 CAM70196.2 - 0.0039 16.7 0.0 0.01 15.3 0.0 1.7 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family EF-hand_4 PF12763.2 CAM70196.2 - 0.035 13.8 0.4 0.25 11.0 0.3 2.3 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand ATG13 PF10033.4 CAM70196.2 - 0.064 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Autophagy-related protein 13 zf-CHCC PF10276.4 CAM70197.1 - 2e-05 24.3 1.2 2e-05 24.3 0.9 2.0 2 0 0 2 2 2 1 Zinc-finger domain Gp_dh_C PF02800.15 CAM70198.1 - 1.7e-66 222.4 0.1 2.8e-66 221.8 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CAM70198.1 - 1.7e-53 180.6 0.9 2.7e-53 179.9 0.6 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 CAM70198.1 - 0.051 14.0 0.1 0.1 13.1 0.1 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Gp_dh_C PF02800.15 CAM70199.1 - 1.7e-66 222.4 0.1 2.8e-66 221.8 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CAM70199.1 - 1.7e-53 180.6 0.9 2.7e-53 179.9 0.6 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 CAM70199.1 - 0.051 14.0 0.1 0.1 13.1 0.1 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DUF2817 PF10994.3 CAM70200.1 - 4.1e-104 348.3 0.1 4.8e-104 348.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) AstE_AspA PF04952.9 CAM70200.1 - 0.00015 20.7 0.0 0.00026 19.9 0.0 1.4 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Peptidase_M14 PF00246.19 CAM70200.1 - 0.0076 15.8 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase TPR_1 PF00515.23 CAM70202.1 - 3.2e-106 343.0 36.1 3.8e-08 32.6 0.4 14.8 15 0 0 15 15 15 14 Tetratricopeptide repeat TPR_11 PF13414.1 CAM70202.1 - 6.2e-100 326.9 47.1 5.1e-16 58.0 1.0 8.7 6 1 2 9 9 9 8 TPR repeat TPR_2 PF07719.12 CAM70202.1 - 5.1e-87 278.9 50.6 2.4e-06 27.0 0.4 15.3 15 0 0 15 15 15 14 Tetratricopeptide repeat TPR_8 PF13181.1 CAM70202.1 - 1.4e-53 174.6 17.6 2.8e-05 23.5 0.0 14.9 14 1 1 15 15 15 10 Tetratricopeptide repeat TPR_16 PF13432.1 CAM70202.1 - 1.2e-48 162.8 54.2 1.5e-08 35.0 1.4 10.0 5 3 5 11 11 11 10 Tetratricopeptide repeat TPR_17 PF13431.1 CAM70202.1 - 2.5e-45 148.8 26.8 6.4e-05 22.8 0.0 12.9 13 0 0 13 13 12 9 Tetratricopeptide repeat TPR_12 PF13424.1 CAM70202.1 - 1e-40 137.5 52.2 2.2e-07 30.7 3.4 8.9 3 1 7 10 10 10 9 Tetratricopeptide repeat TPR_9 PF13371.1 CAM70202.1 - 1.5e-40 136.8 46.8 5e-06 26.2 0.1 11.8 3 2 8 12 12 12 12 Tetratricopeptide repeat TPR_7 PF13176.1 CAM70202.1 - 2.2e-25 86.3 35.0 0.0022 17.6 0.1 13.7 14 0 0 14 14 13 7 Tetratricopeptide repeat TPR_14 PF13428.1 CAM70202.1 - 1.9e-24 83.8 46.1 0.015 15.9 0.1 14.8 3 2 12 15 15 15 6 Tetratricopeptide repeat TPR_6 PF13174.1 CAM70202.1 - 2.5e-21 74.5 39.8 0.1 13.1 0.1 14.2 15 0 0 15 15 15 6 Tetratricopeptide repeat TPR_19 PF14559.1 CAM70202.1 - 2e-16 60.0 29.8 0.0015 18.8 0.0 9.4 7 3 3 10 10 10 6 Tetratricopeptide repeat Apc3 PF12895.2 CAM70202.1 - 1.3e-12 47.6 32.9 2.1e-05 24.5 0.5 7.3 2 2 3 8 8 8 5 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 CAM70202.1 - 8.1e-09 34.5 25.5 1.6 8.0 0.1 10.5 12 0 0 12 12 12 4 SHNi-TPR MIT PF04212.13 CAM70202.1 - 0.00041 20.1 30.6 0.14 12.0 0.0 9.0 9 2 1 10 10 10 2 MIT (microtubule interacting and transport) domain Coatomer_E PF04733.9 CAM70202.1 - 0.00085 18.5 0.5 5.2 6.1 0.0 4.1 4 1 0 4 4 4 1 Coatomer epsilon subunit NARP1 PF12569.3 CAM70202.1 - 0.0099 14.6 12.2 0.017 13.8 0.1 4.8 2 1 4 7 7 7 1 NMDA receptor-regulated protein 1 DUF3856 PF12968.2 CAM70202.1 - 0.012 15.4 16.8 9 6.1 0.3 7.8 6 1 1 8 8 8 0 Domain of Unknown Function (DUF3856) APP_E2 PF12925.2 CAM70202.1 - 0.3 10.6 3.2 3.6 7.1 0.0 3.7 3 1 1 4 4 4 0 E2 domain of amyloid precursor protein TPR_10 PF13374.1 CAM70202.1 - 0.3 11.0 44.3 2.1 8.4 0.2 9.8 10 1 0 10 10 9 0 Tetratricopeptide repeat TPR_20 PF14561.1 CAM70202.1 - 0.51 10.4 16.3 9 6.4 0.0 6.4 5 2 3 8 8 8 0 Tetratricopeptide repeat BTAD PF03704.12 CAM70202.1 - 4.3 7.6 31.0 1.8 8.8 0.3 6.2 4 2 3 7 7 7 0 Bacterial transcriptional activator domain TPR_4 PF07721.9 CAM70202.1 - 5.2 7.7 24.3 3.7 8.2 1.0 8.2 8 0 0 8 8 8 0 Tetratricopeptide repeat LSM PF01423.17 CAM70203.1 - 1e-06 28.1 0.2 1.6e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CAM70203.1 - 0.051 13.5 0.1 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain NHL PF01436.16 CAM70203.1 - 0.076 13.0 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 NHL repeat KH_1 PF00013.24 CAM70204.1 - 0.026 14.1 0.0 0.057 13.0 0.0 1.6 1 0 0 1 1 1 0 KH domain KH_3 PF13014.1 CAM70204.1 - 0.03 13.9 0.0 0.068 12.8 0.0 1.5 1 0 0 1 1 1 0 KH domain DUF1513 PF07433.6 CAM70205.1 - 0.058 12.2 0.0 0.1 11.5 0.0 1.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1513) ATP12 PF07542.6 CAM70205.1 - 0.14 12.1 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 ATP12 chaperone protein DUF21 PF01595.15 CAM70206.1 - 1e-23 83.6 5.5 1.8e-23 82.7 3.8 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 CAM70206.1 - 2.6e-06 27.0 0.0 0.0049 16.6 0.0 2.9 3 0 0 3 3 3 2 CBS domain eIF-3_zeta PF05091.7 CAM70207.1 - 2e-120 402.8 0.0 2.3e-120 402.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pkinase PF00069.20 CAM70208.1 - 1.8e-66 223.9 0.0 2.5e-66 223.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM70208.1 - 2.6e-45 154.5 0.0 4e-45 153.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM70208.1 - 0.00015 20.8 0.0 0.00029 19.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like G8 PF10162.4 CAM70208.1 - 0.00023 20.9 0.8 0.092 12.5 0.0 2.6 2 0 0 2 2 2 2 G8 domain Kinesin PF00225.18 CAM70209.1 - 6.7e-82 274.8 0.0 6.7e-82 274.8 0.0 2.8 3 0 0 3 3 3 1 Kinesin motor domain tRNA_m1G_MT PF01746.16 CAM70210.1 - 4e-25 88.5 0.0 7.4e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase GHMP_kinases_N PF00288.21 CAM70211.1 - 1e-09 38.3 1.2 2.2e-09 37.2 0.9 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CAM70211.1 - 5.3e-07 29.7 0.1 1.3e-06 28.5 0.0 1.7 1 1 0 1 1 1 1 GHMP kinases C terminal CDC27 PF09507.5 CAM70212.1 - 0.16 11.1 7.6 0.22 10.6 5.3 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PAT1 PF09770.4 CAM70212.1 - 1.3 7.1 3.9 1.5 6.9 2.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MOZART2 PF12926.2 CAM70213.1 - 0.012 15.2 0.3 0.12 11.9 0.0 2.7 3 0 0 3 3 3 0 Mitotic-spindle organizing gamma-tubulin ring associated PPR_3 PF13812.1 CAM70213.1 - 0.035 14.3 3.0 51 4.5 0.0 5.5 5 0 0 5 5 5 0 Pentatricopeptide repeat domain Cyclin PF08613.6 CAM70213.1 - 0.13 12.6 0.4 0.73 10.2 0.1 2.1 2 0 0 2 2 2 0 Cyclin DUF3597 PF12200.3 CAM70213.1 - 0.47 10.8 3.2 0.51 10.7 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) SAM_decarbox PF01536.11 CAM70214.1 - 1.5e-120 401.8 0.0 1.8e-120 401.6 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase SAM_decarbox PF01536.11 CAM70215.1 - 5.4e-15 54.8 0.0 2.8e-10 39.3 0.0 2.0 2 0 0 2 2 2 2 Adenosylmethionine decarboxylase tRNA-synt_1 PF00133.17 CAM70216.1 - 9.4e-193 641.4 0.0 4.3e-192 639.3 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CAM70216.1 - 1.5e-37 128.7 0.0 3.1e-37 127.6 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CAM70216.1 - 5e-16 58.3 0.1 1e-07 30.9 0.0 4.0 4 1 0 4 4 4 3 tRNA synthetases class I (M) Val_tRNA-synt_C PF10458.4 CAM70216.1 - 3.8e-15 55.7 1.2 7.8e-15 54.7 0.9 1.6 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1_2 PF13603.1 CAM70216.1 - 9e-09 34.8 0.0 0.00011 21.5 0.0 2.5 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1d PF00750.14 CAM70216.1 - 0.02 13.7 0.1 1.3 7.7 0.0 2.6 3 0 0 3 3 3 0 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 CAM70216.1 - 0.029 13.4 0.6 1.2 8.1 0.1 3.2 4 0 0 4 4 4 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.20 CAM70216.1 - 0.034 13.2 0.0 0.083 12.0 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) ADC PF06314.6 CAM70216.1 - 0.054 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Acetoacetate decarboxylase (ADC) tRNA-synt_1f PF01921.13 CAM70216.1 - 0.065 11.9 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) Laminin_II PF06009.7 CAM70216.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Laminin Domain II MIS13 PF08202.6 CAM70216.1 - 0.13 11.3 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 Mis12-Mtw1 protein family RRM_1 PF00076.17 CAM70217.1 - 1.1e-08 34.5 0.0 1.6e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM70217.1 - 1.1e-07 31.6 0.0 1.7e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM70217.1 - 9e-07 28.6 0.0 1.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Trichoplein PF13868.1 CAM70218.1 - 6e-51 172.8 140.1 6e-51 172.8 97.1 1.8 1 1 0 2 2 2 1 Tumour suppressor, Mitostatin IncA PF04156.9 CAM70219.1 - 0.2 11.2 0.1 0.82 9.2 0.0 2.1 2 0 0 2 2 2 0 IncA protein Cytochrome-c551 PF10643.4 CAM70219.1 - 0.42 9.8 3.0 0.5 9.6 0.9 1.9 2 0 0 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 CPSF_A PF03178.10 CAM70220.1 - 7.6e-62 209.2 0.0 1.3e-61 208.4 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.4 CAM70220.1 - 0.00039 18.6 0.0 0.00074 17.7 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Ribosomal_60s PF00428.14 CAM70221.1 - 2.6e-24 85.4 17.2 3e-24 85.2 11.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein UBACT PF02134.16 CAM70221.1 - 0.1 12.1 0.8 0.2 11.2 0.5 1.4 1 0 0 1 1 1 0 Repeat in ubiquitin-activating (UBA) protein PepSY_2 PF13670.1 CAM70221.1 - 1.6 8.7 9.2 10 6.0 0.0 2.2 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Ribosomal_60s PF00428.14 CAM70222.1 - 3.3e-24 85.1 16.3 3.8e-24 84.8 11.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein UBACT PF02134.16 CAM70222.1 - 0.07 12.7 1.0 0.14 11.7 0.7 1.4 1 0 0 1 1 1 0 Repeat in ubiquitin-activating (UBA) protein PepSY_2 PF13670.1 CAM70222.1 - 1.6 8.7 9.2 10 6.0 0.0 2.2 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain ATP_bind_1 PF03029.12 CAM70223.1 - 0.076 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Fer4_17 PF13534.1 CAM70223.1 - 4.4 7.7 7.4 19 5.6 1.1 2.4 1 1 2 3 3 3 0 4Fe-4S dicluster domain HMG-CoA_red PF00368.13 CAM70224.1 - 2.5e-153 510.1 3.5 2.9e-153 509.9 2.4 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Ribosomal_S26e PF01283.14 CAM70225.1 - 7.5e-41 138.9 3.6 7.9e-41 138.8 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e zf-CCHC_4 PF14392.1 CAM70225.1 - 0.47 10.1 2.8 0.77 9.4 0.1 2.2 2 0 0 2 2 2 0 Zinc knuckle DUF2274 PF10038.4 CAM70226.1 - 0.006 16.6 0.9 0.029 14.4 0.6 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2274) Endonuc-PvuII PF09225.5 CAM70229.1 - 0.066 12.8 0.0 0.073 12.7 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease PvuII tRNA-synt_1c PF00749.16 CAM70230.1 - 7e-100 333.7 0.1 9.8e-100 333.2 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 CAM70230.1 - 1.9e-35 122.1 0.2 3.9e-35 121.0 0.1 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain DUF3832 PF12909.2 CAM70230.1 - 0.0019 18.1 0.0 0.0068 16.4 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3832) Helicase_C PF00271.26 CAM70231.2 - 4e-12 45.8 0.0 1.3e-11 44.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.18 CAM70231.2 - 7.8e-11 41.8 1.6 9.2e-11 41.6 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.24 CAM70231.2 - 4.7e-09 35.9 0.0 2.3e-08 33.7 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 CAM70231.2 - 1.9e-07 30.8 0.0 5.1e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 CAM70231.2 - 1.5e-06 28.3 0.1 1.9e-05 24.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 CAM70231.2 - 0.00043 19.2 0.8 0.00096 18.1 0.6 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein KaiC PF06745.8 CAM70231.2 - 0.014 14.5 0.1 0.12 11.4 0.0 2.4 2 0 0 2 2 2 0 KaiC ResIII PF04851.10 CAM70231.2 - 0.17 11.6 5.4 1.9 8.2 0.0 3.2 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_23 PF13476.1 CAM70231.2 - 3.9 7.7 0.0 3.9 7.7 0.0 3.1 2 1 0 2 2 2 0 AAA domain Ank_2 PF12796.2 CAM70232.1 - 2.4e-44 149.5 7.4 7.5e-20 71.0 0.1 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 CAM70232.1 - 1.3e-35 119.3 10.2 2.8e-07 29.9 0.0 7.6 7 1 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 CAM70232.1 - 1.7e-35 120.7 6.7 4.2e-10 39.8 0.0 6.5 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 CAM70232.1 - 2.3e-29 100.7 10.3 3e-09 36.8 0.5 7.8 4 1 4 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CAM70232.1 - 4.6e-27 91.3 4.0 0.00016 21.6 0.0 8.3 8 0 0 8 8 8 7 Ankyrin repeat BTD PF09270.5 CAM70232.1 - 0.044 13.5 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 Beta-trefoil DNA-binding domain FlgN PF05130.7 CAM70232.1 - 0.13 12.5 0.1 0.13 12.5 0.1 3.3 3 1 0 3 3 3 0 FlgN protein Metallophos PF00149.23 CAM70234.1 - 4.5e-11 42.5 0.5 8.8e-11 41.5 0.3 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase ubiquitin PF00240.18 CAM70236.1 - 7.5e-13 47.6 0.0 1.6e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.6 CAM70236.1 - 1.4e-10 40.4 0.2 2.8e-10 39.4 0.1 1.5 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.26 CAM70236.1 - 4.3e-08 32.7 2.6 1.1e-05 25.1 0.3 2.5 2 0 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.3 CAM70236.1 - 1.8e-07 30.7 0.1 9.9e-07 28.3 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.5 CAM70236.1 - 0.011 16.3 0.0 0.028 14.9 0.0 1.8 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD UBA_3 PF09288.5 CAM70236.1 - 0.026 14.1 0.0 0.073 12.6 0.0 1.7 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain MORN PF02493.15 CAM70237.1 - 1.5e-93 301.2 106.7 2.5e-10 39.4 1.7 15.1 15 0 0 15 15 15 15 MORN repeat BAR PF03114.13 CAM70238.1 - 0.00073 19.1 0.4 0.00096 18.7 0.3 1.2 1 0 0 1 1 1 1 BAR domain EF-hand_7 PF13499.1 CAM70242.1 - 2.9e-39 133.0 14.9 2.3e-09 37.2 0.0 7.1 7 0 0 7 7 7 6 EF-hand domain pair EF-hand_1 PF00036.27 CAM70242.1 - 2.1e-36 120.4 12.3 1.4e-05 24.0 0.0 10.6 10 0 0 10 10 10 8 EF hand EF-hand_6 PF13405.1 CAM70242.1 - 4.4e-33 110.1 15.4 1.7e-05 24.3 0.1 10.3 10 0 0 10 10 10 7 EF-hand domain EF-hand_5 PF13202.1 CAM70242.1 - 2.5e-27 92.9 12.1 0.00011 21.3 0.0 8.8 9 0 0 9 9 9 7 EF hand EF-hand_8 PF13833.1 CAM70242.1 - 7.9e-18 63.8 18.0 0.022 14.3 0.0 10.1 8 3 2 10 10 10 6 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CAM70242.1 - 1.1e-10 41.4 1.2 0.0053 16.7 0.0 5.3 4 1 1 5 5 5 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 CAM70242.1 - 0.031 13.9 0.6 37 4.0 0.0 4.1 4 0 0 4 4 4 0 EF hand Tropomyosin PF00261.15 CAM70242.1 - 0.038 13.0 0.1 0.07 12.2 0.1 1.4 1 0 0 1 1 1 0 Tropomyosin Excalibur PF05901.6 CAM70242.1 - 3.9 7.9 5.5 34 4.8 0.0 4.1 4 0 0 4 4 4 0 Excalibur calcium-binding domain PGK PF00162.14 CAM70250.1 - 1.2e-137 458.6 0.1 1.5e-137 458.2 0.1 1.1 1 0 0 1 1 1 1 Phosphoglycerate kinase PAS PF00989.19 CAM70250.1 - 3.7e-07 29.9 0.0 1.6e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 CAM70250.1 - 9.9e-06 25.8 0.0 6.2e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 CAM70250.1 - 8.3e-05 22.5 0.0 0.0005 20.0 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.1 CAM70250.1 - 0.0069 16.2 0.0 0.026 14.3 0.0 2.0 1 0 0 1 1 1 1 PAS domain SpoVS PF04232.7 CAM70250.1 - 0.079 12.5 0.2 0.51 9.9 0.0 2.4 2 1 1 3 3 3 0 Stage V sporulation protein S (SpoVS) CAS_CSE1 PF03378.10 CAM70251.1 - 8.6e-66 222.0 0.0 2.4e-65 220.5 0.0 1.8 2 1 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 CAM70251.1 - 1.7e-48 165.0 0.0 2.6e-48 164.4 0.0 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 CAM70251.1 - 0.027 14.3 0.0 0.11 12.3 0.0 2.1 1 0 0 1 1 1 0 Importin-beta N-terminal domain Xpo1 PF08389.7 CAM70251.1 - 0.042 13.7 3.1 2.4 8.0 0.1 4.1 4 1 0 4 4 4 0 Exportin 1-like protein MCM_N PF14551.1 CAM70251.1 - 0.046 14.2 0.0 1.1 9.7 0.0 2.9 3 0 0 3 3 3 0 MCM N-terminal domain DUF3753 PF12575.3 CAM70251.1 - 0.16 11.7 0.6 8 6.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) WD40 PF00400.27 CAM70253.1 - 3.9e-07 29.7 10.7 0.011 15.5 0.6 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Dynein_heavy PF03028.10 CAM70253.1 - 0.0076 14.3 0.0 0.011 13.8 0.0 1.1 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor Tcp11 PF05794.8 CAM70254.1 - 3.2e-23 82.1 2.0 3.6e-23 82.0 0.2 1.8 2 0 0 2 2 2 1 T-complex protein 11 Glucosamine_iso PF01182.15 CAM70254.1 - 0.02 14.6 0.1 0.047 13.4 0.1 1.6 1 0 0 1 1 1 0 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase MKT1_C PF12246.3 CAM70255.1 - 1.3e-28 99.6 0.0 1.8e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 CAM70255.1 - 4.3e-17 62.2 0.0 8.4e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication DNA_ligase_A_M PF01068.16 CAM70256.1 - 4e-52 176.5 0.0 5.7e-52 176.0 0.0 1.2 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 CAM70256.1 - 2e-39 135.2 0.0 2.9e-39 134.6 0.0 1.3 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 CAM70256.1 - 3.6e-25 88.1 0.0 8.5e-25 86.9 0.0 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 CAM70256.1 - 0.04 13.5 0.9 0.45 10.2 0.0 2.4 2 0 0 2 2 2 0 DNA ligase OB-like domain TPR_11 PF13414.1 CAM70258.1 - 3e-12 46.0 10.9 0.00028 20.4 0.2 4.6 4 1 1 5 5 5 4 TPR repeat TPR_16 PF13432.1 CAM70258.1 - 4.3e-10 39.9 6.4 0.00023 21.7 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 CAM70258.1 - 5.1e-07 29.3 0.5 3.1 8.2 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CAM70258.1 - 8.5e-06 25.9 9.0 0.06 14.0 0.0 4.8 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 CAM70258.1 - 0.00078 18.9 4.3 4.5 7.0 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 CAM70258.1 - 0.00086 19.1 6.3 0.02 14.7 0.1 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 CAM70258.1 - 0.0027 17.4 12.5 0.042 13.7 0.0 5.1 7 0 0 7 7 7 2 Tetratricopeptide repeat SPO22 PF08631.5 CAM70258.1 - 0.02 14.0 0.0 4.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like TPR_19 PF14559.1 CAM70258.1 - 0.049 13.9 5.7 0.49 10.7 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 CAM70258.1 - 0.06 13.4 0.9 0.19 11.8 0.1 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Yippee-Mis18 PF03226.9 CAM70259.1 - 3.9e-14 52.4 0.3 4.9e-14 52.1 0.2 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-ribbon_3 PF13248.1 CAM70259.1 - 0.16 11.2 1.9 5 6.4 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Pkinase PF00069.20 CAM70260.1 - 8.4e-30 103.7 0.0 1.1e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM70260.1 - 1.2e-11 44.1 0.0 1.5e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Glyco_hydro_98M PF08306.6 CAM70260.1 - 0.092 11.4 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 98 Kinase-like PF14531.1 CAM70260.1 - 0.13 11.1 0.0 0.28 10.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 CAM70260.1 - 0.14 11.8 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Rhodanese PF00581.15 CAM70266.1 - 7.9e-06 26.2 0.0 1.3e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain RF-1 PF00472.15 CAM70267.1 - 7.2e-12 45.1 0.0 2.4e-11 43.4 0.0 1.9 2 0 0 2 2 2 1 RF-1 domain Caldesmon PF02029.10 CAM70267.1 - 0.0025 16.3 0.6 0.0057 15.1 0.4 1.5 1 0 0 1 1 1 1 Caldesmon CARD PF00619.16 CAM70267.1 - 0.0079 16.0 0.1 0.028 14.2 0.1 1.9 1 0 0 1 1 1 1 Caspase recruitment domain Rad54_N PF08658.5 CAM70267.1 - 0.79 9.4 4.4 0.44 10.2 1.2 1.8 2 0 0 2 2 2 0 Rad54 N terminal p450 PF00067.17 CAM70268.1 - 3.4e-49 167.6 0.0 4.8e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Mago_nashi PF02792.9 CAM70269.1 - 5.6e-54 181.7 0.2 6.5e-54 181.5 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein zf-CCCH PF00642.19 CAM70270.1 - 6.3e-06 25.7 2.4 1.5e-05 24.5 1.7 1.7 1 1 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pkinase PF00069.20 CAM70271.1 - 9.9e-37 126.4 0.0 4.6e-17 62.0 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAM70271.1 - 1.7e-09 37.1 0.0 1.2e-05 24.4 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Ribosomal_S11 PF00411.14 CAM70272.1 - 2.8e-41 140.1 0.6 3.5e-41 139.8 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF814 PF05670.8 CAM70272.1 - 0.027 14.3 0.0 0.036 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF814) ATP-synt_DE_N PF02823.11 CAM70273.1 - 1.9e-16 59.5 0.0 3.3e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ATP-synt_DE PF00401.15 CAM70273.1 - 0.1 12.4 4.1 0.15 11.9 2.8 1.2 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain L27_1 PF09058.5 CAM70273.1 - 0.12 12.2 0.7 0.5 10.2 0.0 2.2 3 0 0 3 3 3 0 L27_1 DUF773 PF05600.7 CAM70274.1 - 3.6e-16 59.0 8.4 3.9e-10 39.1 0.5 3.3 1 1 2 3 3 3 3 Protein of unknown function (DUF773) Chordopox_A30L PF06015.7 CAM70274.1 - 0.034 13.7 0.1 0.075 12.6 0.1 1.5 1 0 0 1 1 1 0 Chordopoxvirus A30L protein AAA_27 PF13514.1 CAM70274.1 - 0.069 10.8 15.6 0.044 11.4 2.0 2.1 2 0 0 2 2 2 0 AAA domain Prefoldin_2 PF01920.15 CAM70274.1 - 0.13 11.9 3.8 9.3 6.0 0.4 2.7 2 0 0 2 2 2 0 Prefoldin subunit DUF724 PF05266.9 CAM70274.1 - 7.2 6.1 8.2 15 5.1 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Cyclin PF08613.6 CAM70276.1 - 9.1e-20 71.5 0.0 1.3e-19 71.1 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CAM70276.1 - 4.6e-07 29.4 0.1 7.3e-07 28.7 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain LRR_4 PF12799.2 CAM70277.1 - 2.2e-17 62.2 9.3 3.5e-05 23.2 0.0 3.6 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM70277.1 - 2.2e-10 40.1 13.1 1.9e-07 30.7 2.9 3.1 1 1 2 3 3 3 3 Leucine rich repeat LRR_9 PF14580.1 CAM70277.1 - 1.1e-09 38.1 1.1 1.4e-06 27.9 0.1 2.6 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.28 CAM70277.1 - 0.00043 19.9 9.2 2 8.7 0.0 5.2 2 1 1 3 3 3 2 Leucine Rich Repeat LRR_6 PF13516.1 CAM70277.1 - 0.0018 18.1 9.6 0.18 11.9 0.0 4.8 2 1 3 5 5 5 2 Leucine Rich repeat LRR_7 PF13504.1 CAM70277.1 - 0.0023 17.8 10.0 6.7 7.3 0.2 5.8 3 1 1 4 4 4 2 Leucine rich repeat Ribosomal_L15e PF00827.12 CAM70278.1 - 6.8e-90 299.7 9.1 7.7e-90 299.5 6.3 1.0 1 0 0 1 1 1 1 Ribosomal L15 ATP-synt_C PF00137.16 CAM70279.1 - 2e-26 91.6 40.7 1.6e-15 56.6 7.7 2.7 3 0 0 3 3 3 2 ATP synthase subunit C SnoaL_2 PF12680.2 CAM70280.1 - 1.8e-05 25.0 0.1 3.6e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 SnoaL-like domain SnoaL_3 PF13474.1 CAM70280.1 - 5.7e-05 23.1 0.1 0.00013 21.9 0.0 1.6 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 CAM70280.1 - 0.0013 18.9 0.0 0.012 15.8 0.0 2.0 1 1 0 2 2 2 1 Domain of unknown function (DUF4440) SnoaL PF07366.7 CAM70280.1 - 0.0027 17.2 0.0 0.0053 16.3 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DUF3808 PF10300.4 CAM70282.1 - 9.2e-28 97.0 4.8 1.1e-26 93.4 2.9 2.7 1 1 1 2 2 2 1 Protein of unknown function (DUF3808) TPR_12 PF13424.1 CAM70282.1 - 2.6e-13 49.6 0.8 2.1e-06 27.5 0.3 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 CAM70282.1 - 9.5e-10 37.9 6.2 0.0075 15.8 0.2 4.1 4 0 0 4 4 4 3 TPR repeat TPR_2 PF07719.12 CAM70282.1 - 2.2e-08 33.3 6.1 0.03 14.2 0.3 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 CAM70282.1 - 2.5e-07 30.9 0.0 0.28 11.5 0.0 5.1 4 1 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 CAM70282.1 - 5e-07 29.7 3.2 0.0049 16.9 0.3 3.9 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 CAM70282.1 - 1.1e-05 25.9 0.8 1.2 9.8 0.8 4.8 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 CAM70282.1 - 1.7e-05 25.0 0.1 2.7 8.8 0.1 5.5 6 1 1 7 7 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 CAM70282.1 - 0.0001 21.7 0.1 1.9 8.2 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 CAM70282.1 - 0.00013 22.1 4.9 0.63 10.6 0.1 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 CAM70282.1 - 0.0023 17.5 7.9 4.3 7.3 0.1 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF2225 PF09986.4 CAM70282.1 - 0.088 12.2 5.3 0.31 10.4 0.4 3.0 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_10 PF13374.1 CAM70282.1 - 1.1 9.3 5.5 14 5.7 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TRAP_beta PF05753.9 CAM70284.1 - 7.6e-17 61.0 1.9 2.6e-16 59.2 1.3 1.8 1 1 0 1 1 1 1 Translocon-associated protein beta (TRAPB) DUF11 PF01345.13 CAM70284.1 - 3.9e-08 33.2 0.1 3.9e-08 33.2 0.1 2.5 2 1 0 2 2 2 1 Domain of unknown function DUF11 CARDB PF07705.6 CAM70284.1 - 8.8e-07 28.9 0.7 1.3e-06 28.3 0.5 1.2 1 0 0 1 1 1 1 CARDB NPCBM_assoc PF10633.4 CAM70284.1 - 0.0016 18.4 0.7 0.011 15.7 0.2 2.4 1 1 1 2 2 2 1 NPCBM-associated, NEW3 domain of alpha-galactosidase Nuc_recep-AF1 PF11825.3 CAM70285.1 - 0.087 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Nuclear/hormone receptor activator site AF-1 Ribosomal_L6 PF00347.18 CAM70294.2 - 6.1e-29 100.3 3.8 7.3e-16 58.4 0.4 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Hormone_2 PF00123.15 CAM70294.2 - 0.12 12.2 0.0 30 4.5 0.0 3.1 3 0 0 3 3 3 0 Peptide hormone YbbR PF07949.7 CAM70294.2 - 1 9.5 4.0 5.1 7.2 0.2 2.8 2 2 0 2 2 2 0 YbbR-like protein EF-hand_7 PF13499.1 CAM70298.2 - 0.00012 22.0 0.5 0.0027 17.7 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CAM70298.2 - 0.019 14.8 0.0 0.064 13.1 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.27 CAM70298.2 - 0.049 12.9 0.2 0.2 11.0 0.0 2.2 3 0 0 3 3 3 0 EF hand EF-hand_5 PF13202.1 CAM70298.2 - 0.067 12.5 0.1 0.13 11.6 0.1 1.5 1 0 0 1 1 1 0 EF hand Meth_synt_2 PF01717.13 CAM70317.1 - 8.3e-146 485.0 0.0 9.4e-138 458.5 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 CAM70317.1 - 2e-127 424.7 0.0 2.3e-111 372.0 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain MIP PF00230.15 CAM70318.1 - 5e-48 163.5 9.8 6.3e-48 163.2 6.8 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF4407 PF14362.1 CAM70318.1 - 3.5 6.4 4.6 5.8 5.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) RINGv PF12906.2 CAM70319.1 - 8.3e-12 44.9 5.1 8.3e-12 44.9 3.6 2.1 2 0 0 2 2 2 1 RING-variant domain Pro_isomerase PF00160.16 CAM70321.1 - 3.9e-44 150.5 0.0 4.9e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ResIII PF04851.10 CAM70323.1 - 1.2e-13 51.2 0.0 1.5e-12 47.7 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T5orf172 PF10544.4 CAM70323.1 - 9.6e-09 35.5 0.0 2.9e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 T5orf172 domain DEAD PF00270.24 CAM70323.1 - 1.6e-08 34.2 0.0 2.8e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM70323.1 - 8.8e-06 25.5 0.0 2.1e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CAM70323.1 - 0.00095 18.0 0.0 0.0067 15.2 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain MUG113 PF13455.1 CAM70323.1 - 0.0057 17.0 0.6 0.02 15.3 0.1 2.2 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 DUF3505 PF12013.3 CAM70323.1 - 0.0072 16.5 0.5 0.026 14.7 0.4 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) DUF3638 PF12340.3 CAM70323.1 - 0.12 11.2 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) zf-CCCH PF00642.19 CAM70324.1 - 0.00039 20.0 12.8 0.0021 17.6 2.6 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CAM70324.1 - 0.11 12.4 10.9 0.7 9.9 3.5 2.3 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Peptidase_C33 PF05412.7 CAM70325.1 - 0.056 13.2 0.0 0.31 10.8 0.0 2.1 2 0 0 2 2 2 0 Equine arterivirus Nsp2-type cysteine proteinase Peptidase_M22 PF00814.20 CAM70326.1 - 5e-84 281.9 0.0 5.9e-84 281.7 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family FG-GAP PF01839.18 CAM70327.1 - 2.2e-14 52.6 25.1 0.013 15.1 0.0 6.7 6 0 0 6 6 6 6 FG-GAP repeat VCBS PF13517.1 CAM70327.1 - 1.4e-09 38.1 28.5 9.2e-05 22.7 3.1 7.1 6 2 3 9 9 9 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PQQ_2 PF13360.1 CAM70327.1 - 0.00032 20.2 0.8 0.55 9.6 0.0 2.7 1 1 1 2 2 2 2 PQQ-like domain TcdB_toxin_midN PF12256.3 CAM70327.1 - 0.0057 16.1 7.4 0.2 11.0 0.5 4.0 3 1 1 4 4 4 1 Insecticide toxin TcdB middle/N-terminal region BBS2_C PF14782.1 CAM70327.1 - 0.011 14.3 0.2 2.4 6.6 0.0 2.9 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, C-terminal DUF972 PF06156.8 CAM70329.1 - 0.33 11.2 0.1 0.33 11.2 0.1 7.3 3 2 4 7 7 7 0 Protein of unknown function (DUF972) Filament PF00038.16 CAM70329.1 - 1.4 8.2 80.7 4.2 6.7 23.5 2.9 1 1 1 2 2 2 0 Intermediate filament protein UPF0262 PF06793.7 CAM70331.1 - 0.036 13.7 0.1 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0262) RNA_pol_Rpb2_6 PF00562.23 CAM70332.1 - 2.3e-117 392.0 0.0 3e-117 391.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CAM70332.1 - 9.9e-40 135.6 0.0 1.6e-39 134.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 CAM70332.1 - 1.8e-28 98.6 0.0 1.1e-27 96.0 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 CAM70332.1 - 5.6e-24 84.5 0.0 9.5e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 CAM70332.1 - 1.1e-22 79.5 1.9 2.4e-22 78.4 1.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 CAM70332.1 - 9.4e-20 70.1 1.3 1.6e-19 69.4 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 CAM70332.1 - 6.8e-09 35.5 0.6 1.4e-08 34.5 0.4 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Nol1_Nop2_Fmu PF01189.12 CAM70335.1 - 1e-85 287.5 0.0 1.8e-85 286.7 0.0 1.4 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 CAM70335.1 - 9.3e-06 25.6 1.1 2.8e-05 24.1 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain FtsJ PF01728.14 CAM70335.1 - 0.0001 22.3 0.0 0.00023 21.1 0.0 1.7 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 CAM70335.1 - 0.0005 19.6 0.0 0.00095 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAM70335.1 - 0.0041 17.6 1.9 0.032 14.8 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.11 CAM70335.1 - 0.021 14.3 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein PCMT PF01135.14 CAM70335.1 - 0.027 13.9 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) WD40 PF00400.27 CAM70336.1 - 1.4e-30 104.0 9.3 2e-07 30.6 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat NLE PF08154.7 CAM70336.1 - 1.3e-12 47.5 0.3 2.1e-12 46.8 0.2 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Lactonase PF10282.4 CAM70336.1 - 0.032 13.3 0.0 0.067 12.2 0.0 1.4 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Daxx PF03344.10 CAM70338.1 - 0.01 14.4 16.9 0.011 14.2 11.7 1.0 1 0 0 1 1 1 1 Daxx Family SDA1 PF05285.7 CAM70338.1 - 0.034 13.4 17.1 0.043 13.0 11.9 1.2 1 0 0 1 1 1 0 SDA1 CSTF2_hinge PF14327.1 CAM70338.1 - 0.081 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 Nop14 PF04147.7 CAM70338.1 - 0.093 10.6 22.6 0.1 10.5 15.7 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 CAM70338.1 - 0.25 9.3 13.5 0.3 9.0 9.4 1.2 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.10 CAM70338.1 - 0.52 8.8 4.7 0.57 8.7 3.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TFIIF_alpha PF05793.7 CAM70338.1 - 0.62 8.3 16.3 0.68 8.2 11.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.5 CAM70338.1 - 0.75 8.8 18.8 0.95 8.4 13.0 1.2 1 0 0 1 1 1 0 BUD22 Spore_coat_CotO PF14153.1 CAM70338.1 - 1.1 8.6 4.7 1.3 8.4 3.3 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Osteopontin PF00865.13 CAM70338.1 - 4.3 6.4 25.8 5.9 6.0 17.9 1.1 1 0 0 1 1 1 0 Osteopontin Ebola_NP PF05505.7 CAM70338.1 - 4.6 5.1 11.2 5.2 4.9 7.7 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein DUF2146 PF10220.4 CAM70338.1 - 6.3 4.6 6.2 6.2 4.6 4.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) TPR_MLP1_2 PF07926.7 CAM70339.1 - 2.2e-08 33.8 2.8 2.2e-08 33.8 1.9 8.8 1 1 6 8 8 8 1 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 CAM70339.1 - 0.067 12.3 38.2 0.31 10.1 0.8 7.0 1 1 4 7 7 7 0 Reovirus sigma C capsid protein HrpB_C PF08482.5 CAM70339.1 - 3.5 7.7 8.3 1.4 9.0 0.3 3.6 3 0 0 3 3 3 0 ATP-dependent helicase C-terminal Cupin_4 PF08007.7 CAM70340.1 - 3.8e-40 138.0 0.0 8.4e-39 133.6 0.0 2.0 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_8 PF13621.1 CAM70340.1 - 1.6e-08 34.3 0.0 6.8e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.6 CAM70340.1 - 0.022 14.2 0.0 0.077 12.5 0.0 1.9 1 0 0 1 1 1 0 Cupin domain 2OG-FeII_Oxy PF03171.15 CAM70340.1 - 0.051 13.8 0.1 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Tetraspannin PF00335.15 CAM70340.1 - 0.18 11.0 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Tetraspanin family Helicase_C PF00271.26 CAM70341.1 - 3.4e-09 36.4 0.0 8.4e-09 35.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAM70341.1 - 2.8e-07 30.1 0.0 7.1e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase HA2 PF04408.18 CAM70341.1 - 0.0048 16.8 0.0 0.016 15.1 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) 2OG-FeII_Oxy_3 PF13640.1 CAM70344.1 - 4.7e-17 62.3 0.0 8.8e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 CAM70344.1 - 2.1e-05 24.0 0.0 4.3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Tet_JBP PF12851.2 CAM70344.1 - 0.093 12.0 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily COPIIcoated_ERV PF07970.7 CAM70345.1 - 1.4e-21 77.1 0.0 2.2e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CAM70345.1 - 2.7e-07 30.4 0.0 5.8e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Kinesin PF00225.18 CAM70346.1 - 5.1e-89 298.2 0.5 1.5e-88 296.7 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain Med30 PF11315.3 CAM70346.1 - 0.14 12.2 1.0 1.7 8.7 0.2 2.5 2 0 0 2 2 2 0 Mediator complex subunit 30 TMF_DNA_bd PF12329.3 CAM70346.1 - 1.9 8.3 7.0 0.25 11.1 1.1 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CRAL_TRIO PF00650.15 CAM70347.1 - 7.8e-13 48.2 0.0 1.5e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain Abhydrolase_6 PF12697.2 CAM70347.1 - 0.013 15.3 0.1 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family IncA PF04156.9 CAM70347.1 - 0.084 12.4 0.0 0.084 12.4 0.0 3.6 3 1 0 4 4 4 0 IncA protein CRAL_TRIO PF00650.15 CAM70348.1 - 2.7e-15 56.1 0.0 4.2e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Peptidase_C2 PF00648.16 CAM70368.1 - 5.3e-46 156.9 0.0 8.2e-46 156.3 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 CAM70368.1 - 2.3e-22 78.9 0.0 5.8e-22 77.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Amastin PF07344.6 CAM70369.1 - 3.4e-51 172.9 9.7 4e-51 172.6 6.7 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CAM70369.1 - 8.1e-05 22.3 7.9 8.1e-05 22.3 5.5 1.6 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF4064 PF13273.1 CAM70369.1 - 1.5 8.9 8.2 5.5 7.1 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF4064) SUR7 PF06687.7 CAM70369.1 - 4.1 6.9 11.9 0.7 9.4 3.4 2.2 2 0 0 2 2 2 0 SUR7/PalI family TraL PF07178.6 CAM70369.1 - 7 6.7 6.4 3.5 7.7 0.0 2.6 2 1 0 2 2 2 0 TraL protein Peptidase_C2 PF00648.16 CAM70371.1 - 1.3e-57 195.0 0.0 1.8e-57 194.6 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 CAM70371.1 - 3e-20 72.1 0.2 5.9e-20 71.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) A2M_recep PF07677.9 CAM70371.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 A-macroglobulin receptor AAA_16 PF13191.1 CAM70372.1 - 0.011 15.7 0.1 0.023 14.6 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 CAM70372.1 - 0.043 13.7 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain cNMP_binding PF00027.24 CAM70374.1 - 7.6e-24 83.3 0.0 9.1e-06 25.3 0.0 5.0 4 1 0 4 4 4 4 Cyclic nucleotide-binding domain Peptidase_C2 PF00648.16 CAM70375.1 - 1.9e-31 109.2 0.0 2.7e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 CAM70375.1 - 9.2e-24 83.4 0.0 1.7e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DivIC PF04977.10 CAM70375.1 - 0.035 13.5 0.4 0.064 12.7 0.3 1.3 1 0 0 1 1 1 0 Septum formation initiator Aa_trans PF01490.13 CAM70376.1 - 4.4e-48 163.7 34.4 5.8e-48 163.3 23.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CAM70376.1 - 1.5e-07 30.6 14.4 1.5e-07 30.6 10.0 2.2 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family Aa_trans PF01490.13 CAM70377.1 - 7.3e-42 143.2 33.5 9.8e-42 142.8 23.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1145 PF06611.7 CAM70377.1 - 8.8 6.0 9.4 16 5.2 0.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1145) FA_hydroxylase PF04116.8 CAM70378.1 - 7.2e-10 39.2 13.3 7.2e-10 39.2 9.2 2.0 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily SPC12 PF06645.8 CAM70379.1 - 0.0053 16.5 0.3 0.011 15.4 0.2 1.5 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Ribosomal_L7Ae PF01248.21 CAM70380.1 - 4.1e-05 23.0 0.0 0.0001 21.7 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Antimicrobial19 PF08225.6 CAM70380.1 - 0.0083 15.4 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Pseudin antimicrobial peptide DUF2201_N PF13203.1 CAM70382.1 - 0.039 13.1 0.2 0.039 13.1 0.1 3.3 3 0 0 3 3 3 0 Putative metallopeptidase domain Secretin_N PF03958.12 CAM70382.1 - 0.054 13.6 0.0 1.6 8.9 0.0 3.0 2 0 0 2 2 2 0 Bacterial type II/III secretion system short domain FtsJ PF01728.14 CAM70384.1 - 5.1e-45 153.6 0.0 6.8e-45 153.2 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase C2 PF00168.25 CAM70387.1 - 8.4e-21 73.6 0.0 1.3e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 C2 domain CEP76-C2 PF15627.1 CAM70387.1 - 0.15 11.6 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 CEP76 C2 domain DUF3488 PF11992.3 CAM70387.1 - 0.94 8.0 3.5 2.6 6.6 2.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3488) Peptidase_M41 PF01434.13 CAM70389.1 - 9.9e-52 175.4 0.0 2.5e-51 174.1 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CAM70389.1 - 4.1e-34 117.6 0.0 8.6e-34 116.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CAM70389.1 - 0.00015 21.8 0.3 0.19 11.9 0.1 3.0 1 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CAM70389.1 - 0.00053 19.7 0.5 0.13 11.9 0.3 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CAM70389.1 - 0.0014 19.4 0.2 0.0089 16.8 0.0 2.5 3 0 0 3 3 2 1 AAA domain AAA_2 PF07724.9 CAM70389.1 - 0.0018 18.1 0.0 0.0049 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 CAM70389.1 - 0.0058 16.3 1.4 0.029 14.1 1.0 2.2 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 CAM70389.1 - 0.0067 16.4 0.3 0.023 14.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CAM70389.1 - 0.027 13.8 0.9 0.063 12.6 0.6 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.1 CAM70389.1 - 0.035 13.9 0.0 0.095 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 CAM70389.1 - 0.039 12.9 0.0 0.076 12.0 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 CAM70389.1 - 0.073 13.3 0.0 0.29 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 CAM70389.1 - 0.073 13.0 1.9 0.14 12.1 0.3 2.2 2 1 0 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.16 CAM70389.1 - 0.097 11.8 0.3 0.19 10.8 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MFS_1 PF07690.11 CAM70391.1 - 2.4e-08 33.0 53.6 2.5e-08 33.0 18.4 3.8 2 2 0 2 2 2 2 Major Facilitator Superfamily CesT PF05932.8 CAM70393.1 - 1.6e-17 63.4 0.1 1.6e-16 60.2 0.0 2.2 2 0 0 2 2 2 1 Tir chaperone protein (CesT) family DivIC PF04977.10 CAM70393.1 - 0.0041 16.5 1.6 0.0085 15.5 1.1 1.5 1 0 0 1 1 1 1 Septum formation initiator DUF3450 PF11932.3 CAM70393.1 - 0.0074 15.5 1.1 0.011 15.0 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) GAS PF13851.1 CAM70393.1 - 0.028 13.6 0.2 0.039 13.1 0.1 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4200 PF13863.1 CAM70393.1 - 0.028 14.3 2.6 0.045 13.6 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) ADIP PF11559.3 CAM70393.1 - 0.049 13.5 1.0 0.12 12.3 0.7 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Macoilin PF09726.4 CAM70393.1 - 0.061 11.5 0.2 0.074 11.3 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF904 PF06005.7 CAM70393.1 - 0.071 13.4 0.3 0.14 12.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) HTH_19 PF12844.2 CAM70393.1 - 0.088 12.8 0.0 0.43 10.6 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain AIP3 PF03915.8 CAM70394.1 - 0.78 8.5 6.7 0.43 9.4 1.5 1.9 1 1 1 2 2 2 0 Actin interacting protein 3 SCP-1 PF05483.7 CAM70395.1 - 0.0013 16.6 2.4 0.0016 16.3 1.6 1.1 1 0 0 1 1 1 1 Synaptonemal complex protein 1 (SCP-1) Seryl_tRNA_N PF02403.17 CAM70395.1 - 0.14 12.1 5.3 0.11 12.4 2.3 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain COG5 PF10392.4 CAM70395.1 - 0.18 11.7 8.9 0.24 11.3 2.6 2.3 1 1 1 2 2 2 0 Golgi transport complex subunit 5 DUF725 PF05267.7 CAM70395.1 - 0.19 11.6 2.6 8.7 6.2 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF725) C2 PF00168.25 CAM70397.1 - 8.3e-19 67.2 0.1 1.6e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 C2 domain C2 PF00168.25 CAM70398.1 - 1.6e-21 75.9 0.2 2.2e-21 75.4 0.2 1.2 1 0 0 1 1 1 1 C2 domain Lipase_3 PF01764.20 CAM70402.1 - 2.8e-29 101.5 0.0 4.3e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 CAM70402.1 - 0.0022 17.9 0.5 0.0027 17.6 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CAM70402.1 - 0.0066 16.2 0.1 0.0092 15.7 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 CAM70402.1 - 0.063 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) AXE1 PF05448.7 CAM70402.1 - 0.094 11.1 0.2 0.14 10.6 0.1 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Lipase_3 PF01764.20 CAM70403.1 - 4.2e-39 133.3 0.0 5.4e-39 133.0 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 CAM70403.1 - 0.00044 19.6 0.1 0.017 14.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 CAM70403.1 - 0.0014 18.3 0.1 0.0025 17.5 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CAM70403.1 - 0.0023 17.8 0.2 0.0031 17.4 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2048 PF09752.4 CAM70403.1 - 0.0056 15.6 0.0 0.0093 14.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) Esterase PF00756.15 CAM70403.1 - 0.0094 15.3 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.15 CAM70403.1 - 0.044 13.3 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.15 CAM70403.1 - 0.083 13.1 0.1 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF676 PF05057.9 CAM70403.1 - 0.13 11.5 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) HsbA PF12296.3 CAM70404.1 - 0.0021 17.9 1.9 1.4 8.8 0.0 3.0 3 0 0 3 3 3 2 Hydrophobic surface binding protein A PGBA_C PF15437.1 CAM70404.1 - 0.0024 17.9 4.9 0.0024 17.9 3.4 1.9 2 0 0 2 2 2 1 Plasminogen-binding protein pgbA C-terminal CotJB PF12652.2 CAM70404.1 - 0.057 13.5 2.0 1.9 8.6 0.5 3.4 2 2 1 3 3 3 0 CotJB protein Toxin_52 PF15605.1 CAM70404.1 - 0.59 10.0 2.6 4.1 7.3 0.2 2.7 3 0 0 3 3 3 0 Putative toxin 52 GAS PF13851.1 CAM70404.1 - 3.9 6.6 10.7 5.6 6.1 4.9 2.6 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Ras PF00071.17 CAM70405.1 - 4.3e-23 81.4 0.8 5.7e-19 68.0 0.0 2.6 2 1 0 2 2 2 2 Ras family Miro PF08477.8 CAM70405.1 - 3.8e-13 49.9 0.2 1.3e-12 48.2 0.1 1.9 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 CAM70405.1 - 1.3e-07 31.2 0.1 2.1e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 CAM70405.1 - 2.1e-07 30.3 0.0 1.8e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CAM70405.1 - 1.6e-05 24.7 0.0 4.1e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CAM70405.1 - 6.2e-05 22.2 0.2 0.00032 19.9 0.1 2.0 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region cobW PF02492.14 CAM70405.1 - 0.037 13.4 0.1 0.63 9.4 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 CAM70405.1 - 0.14 11.9 1.3 0.39 10.5 0.0 2.3 3 0 0 3 3 3 0 Dynamin family Aa_trans PF01490.13 CAM70406.1 - 7.9e-47 159.6 41.7 9.6e-47 159.3 28.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CAM70406.1 - 5.1e-05 22.2 30.7 0.00011 21.2 21.3 1.6 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family DUF3671 PF12420.3 CAM70406.1 - 0.76 9.7 0.0 0.76 9.7 0.0 4.8 3 2 1 4 4 4 0 Protein of unknown function Aa_trans PF01490.13 CAM70424.2 - 3e-45 154.4 41.2 3.8e-45 154.1 28.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 CAM70424.2 - 2.6e-11 42.7 30.0 2.6e-11 42.7 20.8 2.0 1 1 1 2 2 2 1 Amino acid permease Trp_Tyr_perm PF03222.8 CAM70424.2 - 2.8e-10 39.5 23.3 2.8e-10 39.5 16.1 1.5 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family DUF843 PF05814.6 CAM70424.2 - 6.9 6.5 9.4 0.97 9.2 1.2 2.6 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) Aa_trans PF01490.13 CAM70425.1 - 1.1e-53 182.2 33.1 1.3e-53 181.9 23.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.13 CAM70426.1 - 5.4e-51 173.3 38.5 6.4e-51 173.1 26.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 CAM70426.1 - 2.5e-09 36.1 23.1 2.5e-09 36.1 16.0 2.0 2 0 0 2 2 2 1 Amino acid permease Trp_Tyr_perm PF03222.8 CAM70426.1 - 6.3e-06 25.2 17.6 6.3e-06 25.2 12.2 2.0 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family CRAL_TRIO PF00650.15 CAM70427.1 - 5.2e-13 48.7 0.0 8.3e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 CAM70427.1 - 0.24 11.2 0.0 0.53 10.1 0.0 1.6 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain NHase_beta PF02211.10 CAM70428.1 - 0.14 11.8 0.7 0.31 10.6 0.5 1.5 1 0 0 1 1 1 0 Nitrile hydratase beta subunit Peptidase_C2 PF00648.16 CAM70430.1 - 2.5e-39 135.0 0.0 3.6e-39 134.5 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 CAM70430.1 - 6e-27 93.6 0.0 1.1e-26 92.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.16 CAM70431.1 - 1.7e-23 83.0 0.0 3.2e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 CAM70431.1 - 8.6e-17 61.0 0.1 3.2e-16 59.1 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1935) DUF1935 PF09149.5 CAM70432.1 - 7.2e-18 64.4 0.0 1.3e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.16 CAM70432.1 - 1.9e-13 50.1 0.0 4.5e-13 48.8 0.0 1.6 1 1 0 1 1 1 1 Calpain family cysteine protease DnaJ PF00226.26 CAM70434.1 - 1.5e-22 79.0 0.3 2.7e-22 78.2 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ-X PF14308.1 CAM70434.1 - 0.00073 18.8 0.2 0.0013 18.0 0.2 1.4 1 0 0 1 1 1 1 X-domain of DnaJ-containing TRM13 PF05206.9 CAM70435.1 - 8.9e-63 211.9 0.0 4.5e-61 206.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.3 CAM70435.1 - 2.2e-10 39.7 7.5 2.2e-10 39.7 5.2 2.7 3 0 0 3 3 3 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.7 CAM70435.1 - 5.1e-10 38.8 0.8 1e-09 37.8 0.6 1.5 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.1 CAM70435.1 - 0.055 13.1 4.1 0.3 10.7 2.5 2.5 2 1 0 2 2 2 0 Methyltransferase domain ABC_membrane_2 PF06472.10 CAM70437.1 - 1.4e-79 267.1 5.6 1.4e-79 267.1 3.9 1.4 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 CAM70437.1 - 1.1e-15 58.1 0.0 2.6e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 ABC transporter Med3 PF11593.3 CAM70437.1 - 4.2 6.5 5.1 0.62 9.2 0.4 1.7 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal GHMP_kinases_C PF08544.8 CAM70439.1 - 4.5e-17 62.0 0.2 9e-17 61.0 0.1 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 CAM70439.1 - 4.7e-16 58.6 0.8 1.2e-15 57.3 0.5 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain Dict-STAT-coil PF09267.5 CAM70439.1 - 0.018 15.2 0.4 0.018 15.2 0.3 2.0 3 0 0 3 3 3 0 Dictyostelium STAT, coiled coil YcaO PF02624.11 CAM70439.1 - 0.091 12.2 0.5 1.4 8.3 0.0 2.5 3 0 0 3 3 3 0 YcaO-like family Aa_trans PF01490.13 CAM70440.1 - 4.1e-46 157.2 36.4 5e-46 156.9 25.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CAM70440.1 - 4.3e-12 45.5 14.2 4.3e-12 45.5 9.8 2.1 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family Aa_trans PF01490.13 CAM70441.1 - 1e-46 159.2 41.5 1.2e-46 158.9 28.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CAM70441.1 - 5.1e-05 22.2 30.7 0.00011 21.2 21.3 1.6 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family DUF3671 PF12420.3 CAM70441.1 - 0.76 9.7 0.0 0.76 9.7 0.0 4.8 3 2 2 5 5 5 0 Protein of unknown function KIAA1430 PF13879.1 CAM70442.1 - 1.2e-19 70.5 2.1 1.9e-19 69.8 1.5 1.3 1 0 0 1 1 1 1 KIAA1430 homologue PAPA-1 PF04795.7 CAM70442.1 - 1.1 10.0 9.5 5 7.8 4.9 2.3 2 0 0 2 2 2 0 PAPA-1-like conserved region Imm_superinfect PF14373.1 CAM70443.1 - 0.011 15.2 0.1 0.019 14.5 0.1 1.5 1 0 0 1 1 1 0 Superinfection immunity protein UPF0104 PF03706.8 CAM70443.1 - 0.026 13.8 0.1 0.026 13.8 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) CD20 PF04103.10 CAM70443.1 - 0.051 13.5 0.8 0.072 13.0 0.5 1.3 1 1 0 1 1 1 0 CD20-like family DUF4651 PF15513.1 CAM70443.1 - 0.16 11.4 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4651) Imm_superinfect PF14373.1 CAM70447.1 - 0.012 15.2 0.1 0.021 14.4 0.1 1.5 1 0 0 1 1 1 0 Superinfection immunity protein UPF0104 PF03706.8 CAM70447.1 - 0.016 14.4 0.3 0.016 14.4 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) CD20 PF04103.10 CAM70447.1 - 0.055 13.4 0.8 0.08 12.8 0.5 1.3 1 1 0 1 1 1 0 CD20-like family DUF2244 PF10003.4 CAM70447.1 - 0.13 11.6 0.7 0.17 11.2 0.5 1.1 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) DUF4217 PF13959.1 CAM70452.1 - 0.0033 16.9 0.0 0.0079 15.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) RRM_1 PF00076.17 CAM70454.1 - 7.9e-06 25.4 0.0 1.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM70454.1 - 0.00044 20.1 0.0 0.00082 19.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) YhfH PF14149.1 CAM70454.1 - 0.018 14.8 1.4 0.096 12.4 0.1 2.4 2 0 0 2 2 2 0 YhfH-like protein RRM_1 PF00076.17 CAM70455.1 - 3.3e-08 33.0 0.0 6.3e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM70455.1 - 4.2e-05 23.4 0.0 0.00011 22.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Toxin_52 PF15605.1 CAM70455.1 - 0.02 14.7 0.0 0.048 13.5 0.0 1.6 1 0 0 1 1 1 0 Putative toxin 52 SOBP PF15279.1 CAM70456.1 - 0.29 11.4 11.9 0.5 10.6 8.2 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein SET PF00856.23 CAM70457.1 - 3.1e-05 24.3 0.0 0.0052 17.0 0.0 2.5 3 0 0 3 3 3 2 SET domain BPL_LplA_LipB PF03099.14 CAM70458.1 - 1.4e-15 57.3 0.0 2.7e-15 56.4 0.0 1.5 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Guanylate_cyc_2 PF09778.4 CAM70458.1 - 0.16 11.0 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 Guanylylate cyclase AIP3 PF03915.8 CAM70459.1 - 0.053 12.4 2.4 0.075 11.9 1.6 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 DUF148 PF02520.12 CAM70459.1 - 0.53 10.0 1.1 0.86 9.4 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF148 OmpH PF03938.9 CAM70459.1 - 2.1 8.2 4.5 4 7.3 3.1 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4498 PF14926.1 CAM70461.1 - 3.2e-18 65.7 0.0 6.8e-12 45.0 0.0 4.4 4 1 0 4 4 4 2 Domain of unknown function (DUF4498) EMP24_GP25L PF01105.19 CAM70462.1 - 4.8e-28 98.1 0.0 5.7e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Gypsy PF07253.6 CAM70462.1 - 0.00086 17.7 0.7 0.0013 17.2 0.5 1.1 1 0 0 1 1 1 1 Gypsy protein EMP24_GP25L PF01105.19 CAM70463.1 - 7.5e-20 71.4 0.0 9e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4140 PF13600.1 CAM70463.1 - 0.034 14.6 0.0 0.052 13.9 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF4158 PF13700.1 CAM70463.1 - 0.043 13.3 0.4 0.081 12.4 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4158) Peptidase_M20 PF01546.23 CAM70464.1 - 1.3e-26 93.3 0.1 1.6e-26 92.9 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CAM70464.1 - 4.4e-10 39.2 0.0 8.6e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain TMEM219 PF14940.1 CAM70464.1 - 0.031 13.3 0.1 0.063 12.3 0.1 1.4 1 0 0 1 1 1 0 Transmembrane 219 Peptidase_M20 PF01546.23 CAM70465.1 - 1.5e-28 99.5 0.1 1.9e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CAM70465.1 - 1.2e-08 34.7 0.0 2.2e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain TMEM219 PF14940.1 CAM70465.1 - 0.016 14.3 0.1 0.03 13.4 0.1 1.4 1 0 0 1 1 1 0 Transmembrane 219 Abhydrolase_6 PF12697.2 CAM70466.1 - 6.9e-27 94.8 0.1 9.6e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CAM70466.1 - 1.9e-22 79.6 0.0 5.9e-22 77.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CAM70466.1 - 2.6e-21 75.2 0.0 5.1e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 CAM70466.1 - 4.1e-10 39.2 0.2 2.4e-08 33.4 0.1 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 CAM70466.1 - 1.9e-09 37.4 0.0 2.9e-08 33.5 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 CAM70466.1 - 0.00029 20.3 0.0 0.0077 15.6 0.0 2.1 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.11 CAM70466.1 - 0.00043 19.7 0.1 0.11 11.9 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase DLH PF01738.13 CAM70466.1 - 0.00067 18.9 0.0 0.27 10.4 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 CAM70466.1 - 0.0012 18.4 0.0 0.0022 17.5 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 CAM70466.1 - 0.0053 16.3 0.0 0.0082 15.7 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Esterase PF00756.15 CAM70466.1 - 0.0093 15.4 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.15 CAM70466.1 - 0.0094 16.1 0.1 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Ser_hydrolase PF06821.8 CAM70466.1 - 0.01 15.4 0.0 0.69 9.4 0.0 2.2 1 1 0 2 2 2 0 Serine hydrolase AXE1 PF05448.7 CAM70466.1 - 0.014 13.9 0.8 0.7 8.3 0.0 2.5 2 1 1 3 3 3 0 Acetyl xylan esterase (AXE1) FSH1 PF03959.8 CAM70466.1 - 0.028 13.8 0.0 0.08 12.3 0.0 1.6 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DUF2920 PF11144.3 CAM70466.1 - 0.043 12.8 0.0 1.2 8.0 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2920) Abhydrolase_8 PF06259.7 CAM70466.1 - 0.055 12.9 0.1 0.14 11.6 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase Lipase_3 PF01764.20 CAM70466.1 - 0.065 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) LRR_4 PF12799.2 CAM70468.1 - 1.7e-12 46.6 10.8 0.026 14.1 0.0 7.0 5 1 0 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM70468.1 - 8.4e-05 22.2 11.5 0.26 11.0 0.2 5.2 4 1 1 5 5 5 3 Leucine rich repeat Telomere_reg-2 PF10193.4 CAM70468.1 - 0.063 13.5 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Telomere length regulation protein LRR_1 PF00560.28 CAM70468.1 - 1.5 9.1 21.4 26 5.3 0.5 8.1 7 2 0 7 7 7 0 Leucine Rich Repeat Cyt-b5 PF00173.23 CAM70469.1 - 8.9e-07 28.6 0.0 1.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cyt-b5 PF00173.23 CAM70470.1 - 5.4e-08 32.5 0.0 7.9e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RskA PF10099.4 CAM70470.1 - 0.038 13.7 1.7 0.085 12.5 0.9 1.7 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Kinase-PPPase PF03618.9 CAM70470.1 - 0.1 12.0 0.0 0.12 11.8 0.0 1.0 1 0 0 1 1 1 0 Kinase/pyrophosphorylase Cyt-b5 PF00173.23 CAM70471.1 - 2.5e-05 23.9 0.0 3.7e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Med3 PF11593.3 CAM70471.1 - 6.4 5.8 9.6 7 5.7 6.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Cyt-b5 PF00173.23 CAM70472.1 - 8.8e-09 35.0 0.0 1.3e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cyt-b5 PF00173.23 CAM70473.1 - 2.4e-08 33.6 0.0 4.2e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2721 PF11026.3 CAM70473.1 - 0.065 12.8 0.2 0.1 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF3638 PF12340.3 CAM70474.1 - 1.8e-27 95.7 0.1 5.3e-24 84.4 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3638) DUF3645 PF12359.3 CAM70474.1 - 8.9e-17 59.9 0.5 2.7e-16 58.3 0.4 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) zf-RanBP PF00641.13 CAM70474.1 - 1.5e-08 33.6 20.7 1.7e-05 23.8 3.0 3.5 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others Thioredoxin_8 PF13905.1 CAM70474.1 - 9.3e-05 22.4 0.0 0.00023 21.2 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like ubiquitin PF00240.18 CAM70474.1 - 0.0028 17.0 0.0 0.0065 15.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family MAM33 PF02330.11 CAM70474.1 - 1.8 8.2 0.1 3.5 7.3 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial glycoprotein H_PPase PF03030.11 CAM70475.1 - 2.4e-253 842.4 34.4 3e-253 842.1 23.8 1.1 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase LRR_6 PF13516.1 CAM70476.1 - 7.8e-07 28.5 4.5 0.4 10.8 0.0 5.1 5 0 0 5 5 5 3 Leucine Rich repeat LRR_4 PF12799.2 CAM70476.1 - 0.0014 18.2 3.0 0.015 14.9 0.7 3.1 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CAM70476.1 - 0.0023 17.6 6.6 0.41 10.8 0.1 4.6 4 0 0 4 4 4 1 Leucine Rich Repeat GvpG PF05120.7 CAM70476.1 - 0.032 14.0 0.1 0.079 12.7 0.1 1.6 1 0 0 1 1 1 0 Gas vesicle protein G LRR_7 PF13504.1 CAM70476.1 - 0.048 13.8 3.4 15 6.3 0.0 4.7 4 0 0 4 4 4 0 Leucine rich repeat MT PF12777.2 CAM70479.1 - 1.1e-06 27.6 6.6 1.7e-06 27.0 0.1 2.2 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Syntaxin-6_N PF09177.6 CAM70479.1 - 0.024 15.0 16.6 0.33 11.3 1.0 4.0 4 0 0 4 4 4 0 Syntaxin 6, N-terminal Ribonuc_2-5A PF06479.7 CAM70479.1 - 0.038 13.8 5.1 1.8 8.4 0.1 3.0 4 0 0 4 4 4 0 Ribonuclease 2-5A DUF3138 PF11336.3 CAM70479.1 - 1.5 6.9 9.9 0.07 11.3 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Bacillus_HBL PF05791.6 CAM70479.1 - 1.9 7.8 10.3 3.9 6.8 0.1 3.4 4 0 0 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) RasGAP_C PF03836.10 CAM70479.1 - 2.7 7.6 7.1 6.4 6.4 0.6 3.0 3 0 0 3 3 3 0 RasGAP C-terminus ABC_membrane PF00664.18 CAM70480.1 - 6.4e-56 189.7 31.7 1.4e-28 100.1 7.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CAM70480.1 - 2.2e-46 157.5 0.0 4.5e-23 82.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.1 CAM70480.1 - 1.5e-11 43.6 1.6 3.9e-06 26.2 0.0 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain SMC_N PF02463.14 CAM70480.1 - 9.6e-10 38.0 0.1 0.028 13.6 0.0 4.2 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CAM70480.1 - 8.9e-09 35.7 0.0 0.027 14.4 0.0 4.2 3 1 0 4 4 4 2 AAA domain AAA_25 PF13481.1 CAM70480.1 - 1.3e-08 34.4 0.1 0.0001 21.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 CAM70480.1 - 9.8e-08 32.5 0.0 0.0001 22.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 CAM70480.1 - 4.7e-07 28.9 0.0 0.0047 15.8 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.1 CAM70480.1 - 7e-07 29.4 1.8 0.0028 17.6 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_10 PF12846.2 CAM70480.1 - 7.2e-06 25.6 0.6 0.02 14.3 0.1 2.4 2 0 0 2 2 2 2 AAA-like domain AAA_19 PF13245.1 CAM70480.1 - 9e-06 25.3 1.1 0.0046 16.6 0.1 3.0 2 0 0 2 2 2 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 CAM70480.1 - 1.1e-05 25.0 0.1 0.035 13.5 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 CAM70480.1 - 3.8e-05 23.6 0.2 0.38 10.7 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase ArgK PF03308.11 CAM70480.1 - 4.3e-05 22.4 0.3 0.037 12.8 0.0 2.3 2 0 0 2 2 2 2 ArgK protein Dynamin_N PF00350.18 CAM70480.1 - 0.00012 21.9 0.4 0.025 14.3 0.0 2.3 2 0 0 2 2 2 1 Dynamin family DUF258 PF03193.11 CAM70480.1 - 0.00018 20.7 0.2 0.01 15.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CAM70480.1 - 0.00025 21.1 0.9 0.074 13.1 0.0 3.0 3 0 0 3 3 2 1 AAA domain NACHT PF05729.7 CAM70480.1 - 0.00025 20.7 0.9 0.071 12.7 0.0 3.0 3 0 0 3 3 2 1 NACHT domain DUF87 PF01935.12 CAM70480.1 - 0.00035 20.4 0.9 0.53 10.0 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function DUF87 MobB PF03205.9 CAM70480.1 - 0.00037 20.2 1.1 0.53 9.9 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 CAM70480.1 - 0.00039 21.2 0.0 2.2 9.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 CAM70480.1 - 0.00081 19.8 1.5 1.1 9.7 0.2 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_30 PF13604.1 CAM70480.1 - 0.0011 18.6 0.3 1.2 8.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.1 CAM70480.1 - 0.0016 18.3 0.0 0.2 11.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CAM70480.1 - 0.0038 16.9 0.2 0.44 10.1 0.0 2.6 2 0 0 2 2 2 1 Archaeal ATPase cobW PF02492.14 CAM70480.1 - 0.0082 15.6 2.2 0.72 9.2 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 CAM70480.1 - 0.013 15.8 0.6 4.9 7.4 0.0 2.9 3 0 0 3 3 2 0 AAA domain CAP_GLY PF01302.20 CAM70480.1 - 0.014 15.0 0.4 0.048 13.3 0.2 1.9 1 1 0 1 1 1 0 CAP-Gly domain ATP_bind_1 PF03029.12 CAM70480.1 - 0.021 14.3 0.7 4.7 6.6 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein TrwB_AAD_bind PF10412.4 CAM70480.1 - 0.022 13.4 0.2 1.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Viral_helicase1 PF01443.13 CAM70480.1 - 0.026 14.0 0.1 3.9 6.9 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Adeno_IVa2 PF02456.10 CAM70480.1 - 0.027 13.1 0.0 0.15 10.6 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein RNA_helicase PF00910.17 CAM70480.1 - 0.065 13.4 0.1 2.4 8.3 0.0 2.9 3 0 0 3 3 2 0 RNA helicase ATP-synt_ab PF00006.20 CAM70480.1 - 0.089 12.2 0.3 2.1 7.7 0.0 2.8 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.9 CAM70480.1 - 0.16 11.6 0.2 7.8 6.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 CAM70480.1 - 0.16 11.6 0.3 21 4.8 0.0 2.4 2 0 0 2 2 2 0 NTPase GTP_EFTU PF00009.22 CAM70480.1 - 0.23 10.8 0.2 4.5 6.6 0.0 2.6 3 0 0 3 3 2 0 Elongation factor Tu GTP binding domain DUF924 PF06041.6 CAM70480.1 - 0.24 11.0 2.2 0.73 9.5 0.0 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF924) AAA_14 PF13173.1 CAM70480.1 - 0.38 10.6 1.8 4.7 7.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain Guanylate_kin PF00625.16 CAM70480.1 - 0.42 10.0 0.0 0.81 9.1 0.0 1.4 1 0 0 1 1 1 0 Guanylate kinase DAP3 PF10236.4 CAM70480.1 - 1.6 7.6 2.4 22 3.8 0.0 2.6 3 0 0 3 3 2 0 Mitochondrial ribosomal death-associated protein 3 ABC_ATPase PF09818.4 CAM70480.1 - 1.8 7.0 3.6 0.95 7.9 0.1 2.2 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_15 PF13175.1 CAM70480.1 - 1.9 7.4 0.0 19 4.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 CAM70481.1 - 9e-47 158.8 0.0 4e-23 82.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CAM70481.1 - 3.5e-40 138.1 17.2 1.6e-23 83.5 4.6 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_29 PF13555.1 CAM70481.1 - 1.6e-11 43.5 0.1 3.7e-06 26.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 CAM70481.1 - 1e-09 37.9 0.1 0.025 13.8 0.1 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CAM70481.1 - 5.4e-09 36.4 0.0 0.027 14.4 0.0 4.2 3 1 0 4 4 4 2 AAA domain AAA_25 PF13481.1 CAM70481.1 - 1.6e-08 34.1 0.1 0.00014 21.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 CAM70481.1 - 9.3e-08 32.6 0.0 0.0001 22.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 CAM70481.1 - 4.6e-07 29.0 0.0 0.0055 15.6 0.0 2.5 3 0 0 3 3 2 2 Type II/IV secretion system protein AAA_16 PF13191.1 CAM70481.1 - 8.6e-07 29.1 2.5 0.0016 18.4 0.0 3.3 3 1 0 3 3 2 2 AAA ATPase domain AAA_19 PF13245.1 CAM70481.1 - 4.8e-06 26.2 1.1 0.0046 16.6 0.1 3.5 2 0 0 2 2 2 1 Part of AAA domain AAA_10 PF12846.2 CAM70481.1 - 5.5e-06 26.0 0.6 0.017 14.5 0.1 2.4 2 0 0 2 2 2 2 AAA-like domain FtsK_SpoIIIE PF01580.13 CAM70481.1 - 8.7e-06 25.3 0.1 0.031 13.7 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 CAM70481.1 - 3.4e-05 23.7 0.5 0.37 10.7 0.0 2.7 3 0 0 3 3 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 CAM70481.1 - 0.00011 22.0 0.6 0.025 14.3 0.0 2.5 2 0 0 2 2 2 1 Dynamin family ArgK PF03308.11 CAM70481.1 - 0.00013 20.8 0.3 0.13 11.0 0.0 2.4 2 0 0 2 2 2 2 ArgK protein DUF258 PF03193.11 CAM70481.1 - 0.00025 20.2 0.1 0.018 14.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 NACHT PF05729.7 CAM70481.1 - 0.00028 20.6 0.1 0.075 12.6 0.0 2.4 2 0 0 2 2 2 1 NACHT domain MobB PF03205.9 CAM70481.1 - 0.00029 20.5 1.1 0.48 10.1 0.0 2.9 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 CAM70481.1 - 0.0003 21.6 0.0 1.9 9.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CAM70481.1 - 0.00037 20.6 0.7 0.14 12.2 0.0 3.0 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.12 CAM70481.1 - 0.0004 20.2 1.2 0.48 10.1 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function DUF87 Miro PF08477.8 CAM70481.1 - 0.0013 19.2 2.2 1 9.8 0.2 2.5 2 0 0 2 2 2 2 Miro-like protein AAA_33 PF13671.1 CAM70481.1 - 0.0013 18.5 0.1 0.21 11.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 CAM70481.1 - 0.0035 16.9 3.3 1.1 8.8 0.0 3.4 4 0 0 4 4 2 1 AAA domain Arch_ATPase PF01637.13 CAM70481.1 - 0.0038 16.9 0.1 0.39 10.3 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase AAA_18 PF13238.1 CAM70481.1 - 0.0047 17.2 0.1 4.6 7.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 CAM70481.1 - 0.0077 15.6 2.2 0.66 9.4 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CAP_GLY PF01302.20 CAM70481.1 - 0.012 15.2 0.3 0.043 13.5 0.2 1.9 1 1 0 1 1 1 0 CAP-Gly domain TrwB_AAD_bind PF10412.4 CAM70481.1 - 0.017 13.7 0.2 1.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Viral_helicase1 PF01443.13 CAM70481.1 - 0.029 13.8 0.1 4.5 6.7 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 CAM70481.1 - 0.056 13.6 0.1 2.1 8.5 0.0 2.8 3 0 0 3 3 2 0 RNA helicase Adeno_IVa2 PF02456.10 CAM70481.1 - 0.067 11.8 0.1 0.31 9.6 0.0 1.9 2 0 0 2 2 2 0 Adenovirus IVa2 protein ATP-synt_ab PF00006.20 CAM70481.1 - 0.12 11.8 0.2 1.9 7.9 0.0 2.5 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.10 CAM70481.1 - 0.14 11.8 0.3 19 4.9 0.0 2.4 2 0 0 2 2 2 0 NTPase Zeta_toxin PF06414.7 CAM70481.1 - 0.15 11.1 0.1 8.2 5.4 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin AAA_5 PF07728.9 CAM70481.1 - 0.17 11.5 1.0 7.5 6.2 0.0 2.7 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 CAM70481.1 - 0.27 11.1 0.5 4.3 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 CAM70481.1 - 0.28 10.6 5.5 4.3 6.8 0.1 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 CAM70481.1 - 0.28 10.5 0.1 4.2 6.7 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DAP3 PF10236.4 CAM70481.1 - 0.39 9.6 0.6 12 4.7 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Guanylate_kin PF00625.16 CAM70481.1 - 0.4 10.1 0.0 0.73 9.2 0.0 1.4 1 0 0 1 1 1 0 Guanylate kinase ABC_tran PF00005.22 CAM70482.1 - 1.7e-46 157.8 0.0 4.1e-23 82.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CAM70482.1 - 3e-38 131.7 18.2 3.2e-20 72.6 6.6 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_29 PF13555.1 CAM70482.1 - 1.6e-11 43.5 0.1 3.7e-06 26.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 CAM70482.1 - 9.8e-10 38.0 0.1 0.023 13.9 0.1 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CAM70482.1 - 6.9e-09 36.0 0.0 0.024 14.5 0.0 4.1 3 1 0 4 4 4 2 AAA domain AAA_25 PF13481.1 CAM70482.1 - 1.1e-08 34.7 0.1 8.6e-05 22.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 CAM70482.1 - 8.9e-08 32.7 0.0 9.8e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 CAM70482.1 - 6.1e-07 28.6 0.0 0.0056 15.6 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.1 CAM70482.1 - 9.2e-07 29.0 3.0 0.0015 18.5 0.2 3.3 3 1 0 3 3 2 2 AAA ATPase domain AAA_19 PF13245.1 CAM70482.1 - 5.3e-06 26.1 1.1 0.0042 16.8 0.1 3.3 2 0 0 2 2 2 1 Part of AAA domain AAA_10 PF12846.2 CAM70482.1 - 5.4e-06 26.0 0.6 0.018 14.4 0.1 2.5 2 0 0 2 2 2 2 AAA-like domain FtsK_SpoIIIE PF01580.13 CAM70482.1 - 7.4e-06 25.5 0.1 0.032 13.7 0.0 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 CAM70482.1 - 3.4e-05 23.7 0.2 0.34 10.8 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase ArgK PF03308.11 CAM70482.1 - 4.6e-05 22.3 0.4 0.041 12.6 0.0 2.4 2 0 0 2 2 2 2 ArgK protein Dynamin_N PF00350.18 CAM70482.1 - 9.4e-05 22.2 0.3 0.023 14.5 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AAA_22 PF13401.1 CAM70482.1 - 0.00018 21.6 0.8 0.068 13.3 0.0 3.1 3 0 0 3 3 2 1 AAA domain NACHT PF05729.7 CAM70482.1 - 0.00018 21.1 0.1 0.065 12.8 0.0 2.7 2 0 0 2 2 2 1 NACHT domain DUF258 PF03193.11 CAM70482.1 - 0.00025 20.2 0.1 0.018 14.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MobB PF03205.9 CAM70482.1 - 0.00034 20.3 1.1 0.49 10.1 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 CAM70482.1 - 0.00036 21.3 0.0 2 9.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 CAM70482.1 - 0.00042 20.1 1.2 0.49 10.1 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_18 PF13238.1 CAM70482.1 - 0.00048 20.4 0.0 4.5 7.5 0.0 4.0 4 0 0 4 4 4 0 AAA domain Miro PF08477.8 CAM70482.1 - 0.00077 19.9 1.5 1 9.8 0.2 2.5 2 0 0 2 2 2 2 Miro-like protein AAA_30 PF13604.1 CAM70482.1 - 0.00088 18.9 0.4 1.1 8.8 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.1 CAM70482.1 - 0.0014 18.5 0.0 0.18 11.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CAM70482.1 - 0.0032 17.1 0.1 0.4 10.3 0.0 2.6 2 0 0 2 2 2 1 Archaeal ATPase cobW PF02492.14 CAM70482.1 - 0.0071 15.8 2.2 0.66 9.3 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CAP_GLY PF01302.20 CAM70482.1 - 0.01 15.5 0.6 0.05 13.3 0.4 2.1 1 1 0 1 1 1 0 CAP-Gly domain TrwB_AAD_bind PF10412.4 CAM70482.1 - 0.019 13.6 0.2 1.2 7.6 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ATP_bind_1 PF03029.12 CAM70482.1 - 0.02 14.4 0.7 4.3 6.8 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Viral_helicase1 PF01443.13 CAM70482.1 - 0.023 14.2 0.1 3.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Adeno_IVa2 PF02456.10 CAM70482.1 - 0.054 12.1 0.2 0.31 9.6 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein RNA_helicase PF00910.17 CAM70482.1 - 0.065 13.4 0.1 2.2 8.4 0.0 2.7 3 0 0 3 3 2 0 RNA helicase Zeta_toxin PF06414.7 CAM70482.1 - 0.11 11.6 0.1 8.3 5.4 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin AAA_5 PF07728.9 CAM70482.1 - 0.12 12.0 0.2 7.1 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.20 CAM70482.1 - 0.13 11.7 0.3 1.9 7.9 0.0 2.5 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.10 CAM70482.1 - 0.14 11.8 0.3 19 4.9 0.0 2.4 2 0 0 2 2 2 0 NTPase Guanylate_kin PF00625.16 CAM70482.1 - 0.22 10.9 0.0 0.74 9.2 0.0 1.8 2 0 0 2 2 2 0 Guanylate kinase AAA_14 PF13173.1 CAM70482.1 - 0.26 11.1 0.5 4.4 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 CAM70482.1 - 0.27 10.6 0.0 4.1 6.7 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DAP3 PF10236.4 CAM70482.1 - 0.68 8.8 0.6 22 3.8 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 ABC_ATPase PF09818.4 CAM70482.1 - 2 6.9 4.0 0.87 8.0 0.0 2.3 3 0 0 3 3 3 0 Predicted ATPase of the ABC class PP2C PF00481.16 CAM70485.1 - 1.2e-32 113.3 0.1 3.5e-28 98.6 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C zf-UBP PF02148.14 CAM70485.1 - 0.088 12.9 10.1 0.22 11.6 7.0 1.7 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein CSD PF00313.17 CAM70486.1 - 8.2e-08 31.9 0.0 0.00028 20.6 0.0 2.5 2 0 0 2 2 2 2 'Cold-shock' DNA-binding domain TEX13 PF15186.1 CAM70486.1 - 2.9 7.4 3.6 5.3 6.6 2.5 1.3 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family CSD PF00313.17 CAM70487.1 - 3.4e-11 42.7 0.0 2.9e-07 30.1 0.0 2.7 3 0 0 3 3 3 2 'Cold-shock' DNA-binding domain CSD PF00313.17 CAM70488.1 - 0.0001 22.0 0.2 0.59 9.9 0.0 2.4 2 0 0 2 2 2 2 'Cold-shock' DNA-binding domain PAAR_motif PF05488.8 CAM70488.1 - 2.9 7.9 6.0 0.81 9.7 0.3 3.0 4 0 0 4 4 4 0 PAAR motif DivIC PF04977.10 CAM70489.1 - 0.094 12.2 0.2 0.094 12.2 0.1 4.8 4 2 1 5 5 5 0 Septum formation initiator TMF_TATA_bd PF12325.3 CAM70489.1 - 0.61 9.8 17.4 2.4 7.9 0.1 4.3 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding HlyD PF00529.15 CAM70489.1 - 1 8.6 35.9 2.3 7.4 13.0 2.2 2 0 0 2 2 2 0 HlyD family secretion protein HALZ PF02183.13 CAM70489.1 - 4.6 7.0 20.4 2 8.1 0.2 5.1 5 1 0 5 5 5 0 Homeobox associated leucine zipper SPRY PF00622.23 CAM70490.1 - 0.0002 21.4 0.0 0.00041 20.4 0.0 1.4 1 0 0 1 1 1 1 SPRY domain DUF948 PF06103.6 CAM70490.1 - 9.6 6.1 14.2 7.8 6.4 0.7 4.7 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) zf-LSD1 PF06943.7 CAM70493.1 - 4.6e-12 45.3 5.9 4.6e-12 45.3 4.1 2.9 2 1 1 3 3 3 1 LSD1 zinc finger Mu-like_Com PF10122.4 CAM70493.1 - 0.72 8.9 13.5 0.43 9.6 0.3 2.6 1 1 2 3 3 3 0 Mu-like prophage protein Com Tmemb_55A PF09788.4 CAM70493.1 - 0.92 8.5 17.1 1.8 7.6 11.8 1.4 1 1 0 1 1 1 0 Transmembrane protein 55A zinc_ribbon_4 PF13717.1 CAM70493.1 - 1.1 9.0 0.0 1.1 9.0 0.0 4.0 3 1 1 5 5 5 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CAM70493.1 - 1.1 8.8 16.0 1.1 8.8 0.0 4.0 3 1 1 4 4 4 0 zinc-ribbon domain zf-C3HC4_4 PF15227.1 CAM70493.1 - 2.6 7.9 13.6 5.5 6.9 0.0 3.3 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING zf-MYND PF01753.13 CAM70493.1 - 4.2 7.3 9.6 5.2 7.0 0.1 2.6 2 1 0 2 2 2 0 MYND finger Stc1 PF12898.2 CAM70493.1 - 5.6 7.0 9.1 0.31 11.1 0.4 2.3 1 1 1 2 2 2 0 Stc1 domain HypA PF01155.14 CAM70493.1 - 9.9 5.8 12.3 2.9 7.6 0.7 2.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family ABC_tran PF00005.22 CAM70497.1 - 2.4e-43 147.7 0.0 8.6e-25 87.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CAM70497.1 - 8.4e-35 120.5 14.9 7.3e-22 78.0 0.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 CAM70497.1 - 6.5e-09 35.3 0.2 0.047 12.9 0.0 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CAM70497.1 - 2.6e-07 30.0 0.1 0.021 14.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 CAM70497.1 - 6.1e-07 29.6 0.0 0.93 9.3 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.1 CAM70497.1 - 7.4e-07 29.3 0.2 0.043 13.8 0.0 3.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 CAM70497.1 - 4e-06 26.3 0.1 0.039 13.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 CAM70497.1 - 7e-06 25.1 0.0 0.068 12.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 CAM70497.1 - 1.7e-05 24.4 0.1 0.058 12.8 0.0 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_10 PF12846.2 CAM70497.1 - 3.3e-05 23.4 0.1 0.16 11.3 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain CAP_GLY PF01302.20 CAM70497.1 - 6e-05 22.6 0.0 0.00016 21.2 0.0 1.7 1 0 0 1 1 1 1 CAP-Gly domain AAA_23 PF13476.1 CAM70497.1 - 0.00012 22.4 0.0 0.11 12.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.4 CAM70497.1 - 0.00016 20.4 0.4 0.32 9.5 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain MMR_HSR1 PF01926.18 CAM70497.1 - 0.00068 19.5 0.2 0.41 10.5 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase ArgK PF03308.11 CAM70497.1 - 0.0027 16.5 0.4 1.3 7.7 0.1 2.3 2 0 0 2 2 2 2 ArgK protein Miro PF08477.8 CAM70497.1 - 0.0029 18.1 1.2 1.1 9.7 0.3 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 CAM70497.1 - 0.0034 17.5 0.7 1.8 8.7 0.0 3.1 3 0 0 3 3 2 1 AAA domain MobB PF03205.9 CAM70497.1 - 0.0084 15.8 1.3 1.1 8.9 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 CAM70497.1 - 0.012 15.2 1.3 1.9 8.1 0.0 2.6 2 0 0 2 2 2 0 NACHT domain DUF87 PF01935.12 CAM70497.1 - 0.016 15.0 5.0 0.52 10.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF258 PF03193.11 CAM70497.1 - 0.018 14.2 0.4 1 8.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ATP-synt_ab PF00006.20 CAM70497.1 - 0.026 14.0 1.0 1.1 8.6 0.4 2.6 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.7 CAM70497.1 - 0.031 13.3 0.0 4 6.4 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.14 CAM70497.1 - 0.05 13.0 2.6 3.4 7.0 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 CAM70497.1 - 0.14 11.8 0.0 18 4.9 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase Viral_helicase1 PF01443.13 CAM70497.1 - 0.21 11.1 0.1 17 4.8 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Pox_A32 PF04665.7 CAM70497.1 - 0.23 10.7 0.5 19 4.4 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_33 PF13671.1 CAM70497.1 - 0.28 11.0 3.1 4 7.3 0.1 2.8 3 0 0 3 3 2 0 AAA domain KaiC PF06745.8 CAM70497.1 - 0.29 10.2 0.2 12 4.9 0.0 2.3 2 0 0 2 2 2 0 KaiC DAP3 PF10236.4 CAM70497.1 - 0.33 9.8 0.8 9.3 5.0 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF2075 PF09848.4 CAM70497.1 - 0.46 9.4 0.8 1.7 7.5 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 CAM70497.1 - 0.48 9.2 0.5 12 4.6 0.2 2.2 2 0 0 2 2 2 0 NB-ARC domain AIG1 PF04548.11 CAM70497.1 - 0.55 9.2 1.2 4.5 6.3 0.0 2.4 2 0 0 2 2 2 0 AIG1 family AAA_17 PF13207.1 CAM70497.1 - 0.93 10.3 3.9 5.7 7.7 0.4 2.7 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 CAM70497.1 - 1.1 9.0 3.9 17 5.1 0.2 2.3 2 0 0 2 2 2 0 Dynamin family Adeno_IVa2 PF02456.10 CAM70497.1 - 1.3 7.5 0.0 5.8 5.4 0.0 1.8 2 0 0 2 2 2 0 Adenovirus IVa2 protein LRR_4 PF12799.2 CAM70499.2 - 2.3e-10 39.8 0.0 0.0086 15.6 0.0 3.8 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM70499.2 - 7.2e-09 35.2 0.1 0.0027 17.4 0.1 3.2 2 2 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 CAM70499.2 - 8.7e-05 22.0 0.0 1.3 9.3 0.1 5.3 6 0 0 6 6 6 1 Leucine Rich Repeat LRRNT_2 PF08263.7 CAM70499.2 - 0.075 13.0 0.1 0.075 13.0 0.1 3.0 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain LRR_4 PF12799.2 CAM70500.1 - 8e-09 34.9 0.0 0.056 13.0 0.0 3.4 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM70500.1 - 0.00041 20.0 0.2 0.081 12.6 0.0 2.7 2 0 0 2 2 2 2 Leucine rich repeat DUF605 PF04652.11 CAM70500.1 - 0.071 12.5 24.9 0.1 11.9 17.2 1.2 1 0 0 1 1 1 0 Vta1 like Mucin PF01456.12 CAM70500.1 - 3 7.6 173.8 1.9 8.2 46.2 4.2 2 1 2 4 4 4 0 Mucin-like glycoprotein LRR_4 PF12799.2 CAM70501.1 - 9.6e-09 34.6 4.7 0.00029 20.3 0.2 3.9 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CAM70501.1 - 1.4e-08 33.6 1.0 3 8.2 0.0 7.1 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_8 PF13855.1 CAM70501.1 - 4.9e-07 29.4 1.3 0.0031 17.2 0.1 2.7 2 1 0 2 2 2 2 Leucine rich repeat DUF3338 PF11819.3 CAM70501.1 - 0.1 12.0 0.0 21 4.5 0.0 3.3 1 1 3 4 4 4 0 Domain of unknown function (DUF3338) Kei1 PF08552.6 CAM70502.1 - 0.35 10.5 0.1 0.77 9.3 0.1 1.5 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 LRR_4 PF12799.2 CAM70503.1 - 2.6e-22 77.9 3.6 0.0016 18.0 0.0 10.6 11 1 0 11 11 11 6 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CAM70503.1 - 2e-13 48.9 11.4 0.47 10.6 0.0 12.2 11 2 1 12 12 12 3 Leucine Rich repeat LRR_8 PF13855.1 CAM70503.1 - 7.7e-09 35.1 24.6 0.0015 18.2 0.2 8.8 8 1 1 9 9 9 6 Leucine rich repeat LRR_7 PF13504.1 CAM70503.1 - 1.1 9.7 26.5 6.1 7.5 0.4 11.3 12 0 0 12 12 12 0 Leucine rich repeat SipA PF09052.5 CAM70505.1 - 3.2 6.0 8.2 4.9 5.4 5.7 1.2 1 0 0 1 1 1 0 Salmonella invasion protein A Pkinase PF00069.20 CAM70508.1 - 1.9e-38 132.1 0.0 1.4e-26 93.2 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAM70508.1 - 2.8e-21 75.7 0.0 8e-10 38.2 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase PH_3 PF14593.1 CAM70508.1 - 0.0013 18.5 0.0 0.02 14.7 0.0 2.3 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.1 CAM70508.1 - 0.032 13.1 0.0 0.097 11.6 0.0 1.7 2 0 0 2 2 2 0 Kinase-like L51_S25_CI-B8 PF05047.11 CAM70510.1 - 1.9e-10 40.3 0.0 3.8e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain LysR_substrate PF03466.15 CAM70510.1 - 0.11 11.6 0.3 0.43 9.6 0.0 1.9 2 0 0 2 2 2 0 LysR substrate binding domain TFCD_C PF12612.3 CAM70511.1 - 0.028 13.8 0.1 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal DUF2877 PF11392.3 CAM70511.1 - 0.062 13.5 0.1 0.8 9.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2877) DUF1250 PF06855.7 CAM70511.1 - 0.1 12.1 0.0 1.3 8.5 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1250) DUF1658 PF07871.6 CAM70512.1 - 0.025 14.1 0.0 0.077 12.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1658) Cmc1 PF08583.5 CAM70513.1 - 0.037 13.7 4.3 0.097 12.4 3.0 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Ribosomal_L36 PF00444.13 CAM70514.1 - 0.04 13.9 0.4 0.084 12.8 0.3 1.5 1 0 0 1 1 1 0 Ribosomal protein L36 LRR_4 PF12799.2 CAM70515.1 - 2.3e-48 161.1 24.1 2.2e-05 23.9 0.0 11.8 9 2 2 12 12 12 10 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CAM70515.1 - 1.6e-19 67.7 31.1 0.0067 16.3 0.1 16.9 20 0 0 20 20 20 5 Leucine Rich repeat LRR_8 PF13855.1 CAM70515.1 - 1.2e-13 50.6 36.3 0.00026 20.6 2.1 10.5 4 1 9 14 14 14 8 Leucine rich repeat LRR_1 PF00560.28 CAM70515.1 - 7.1e-05 22.3 27.8 24 5.4 0.9 13.9 15 3 2 17 17 17 1 Leucine Rich Repeat WAP PF00095.16 CAM70515.1 - 0.0006 19.7 0.9 0.0026 17.6 0.6 2.0 1 0 0 1 1 1 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' LRR_9 PF14580.1 CAM70515.1 - 0.054 13.0 7.5 26 4.3 0.1 4.6 2 2 2 4 4 4 0 Leucine-rich repeat TP_methylase PF00590.15 CAM70516.1 - 2.1e-18 66.8 0.0 3.6e-18 66.0 0.0 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF4434 PF14488.1 CAM70516.1 - 0.0049 16.6 0.0 0.0082 15.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4434) NolV PF06635.7 CAM70516.1 - 0.0058 15.8 0.0 0.0097 15.0 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein NolV NTPase_I-T PF01931.13 CAM70517.1 - 4.8e-65 218.3 0.0 5.5e-65 218.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 Flg_bb_rod PF00460.15 CAM70517.1 - 0.047 13.4 0.2 0.078 12.7 0.1 1.4 1 0 0 1 1 1 0 Flagella basal body rod protein Thiolase_N PF00108.18 CAM70518.2 - 4.5e-62 209.4 0.3 6e-62 209.0 0.2 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CAM70518.2 - 2.6e-35 120.5 0.0 8.2e-35 118.9 0.0 1.9 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CAM70518.2 - 6.4e-06 25.8 0.7 1.6e-05 24.4 0.5 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.6 CAM70518.2 - 6.7e-05 21.4 0.1 0.00013 20.5 0.0 1.4 1 0 0 1 1 1 1 Stage V sporulation protein AD (SpoVAD) FAE1_CUT1_RppA PF08392.7 CAM70518.2 - 0.00058 19.0 0.2 0.0012 18.0 0.1 1.4 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III PF08545.5 CAM70518.2 - 0.049 13.2 0.4 2.2 8.0 0.1 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III zf-MYND PF01753.13 CAM70519.1 - 7.9e-11 41.6 8.7 7.9e-11 41.6 6.1 2.1 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.1 CAM70519.1 - 0.87 9.4 8.2 1.3 8.8 4.4 2.2 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Sld5 PF05916.6 CAM70520.1 - 5.8e-06 26.5 0.0 7.5e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Filament PF00038.16 CAM70522.1 - 0.0053 16.2 0.8 0.0083 15.6 0.6 1.3 1 1 0 1 1 1 1 Intermediate filament protein UME PF08064.8 CAM70523.1 - 0.03 14.2 2.2 0.16 11.9 0.1 2.8 3 0 0 3 3 3 0 UME (NUC010) domain PPR_3 PF13812.1 CAM70524.1 - 0.0072 16.5 5.3 1 9.8 0.0 4.7 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 CAM70524.1 - 0.039 13.9 0.6 94 3.1 0.0 4.3 4 0 0 4 4 4 0 PPR repeat family Cullin_Nedd8 PF10557.4 CAM70526.1 - 3e-16 59.0 2.3 6.1e-16 57.9 1.6 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain Cullin PF00888.17 CAM70526.1 - 0.00014 20.6 0.1 0.0026 16.3 0.0 2.5 2 1 0 2 2 2 1 Cullin family NAP PF00956.13 CAM70529.1 - 2.3e-76 256.1 0.4 2.3e-76 256.1 0.3 1.8 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) HAUS6_N PF14661.1 CAM70529.1 - 0.023 14.0 0.4 0.048 13.0 0.3 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus FXR1P_C PF12235.3 CAM70529.1 - 0.023 14.8 6.4 0.023 14.8 4.4 1.9 2 0 0 2 2 2 0 Fragile X-related 1 protein C terminal PBP1_TM PF14812.1 CAM70529.1 - 0.59 10.4 12.8 6.4 7.1 1.4 3.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 CAM70529.1 - 2.3 7.7 14.6 2.5 7.6 4.4 2.6 2 0 0 2 2 2 0 Nucleoplasmin Spt5_N PF11942.3 CAM70529.1 - 6.7 7.4 19.6 17 6.1 4.6 3.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Plasmid_RAQPRD PF09686.5 CAM70530.1 - 0.036 14.1 0.2 0.23 11.5 0.1 2.3 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Lectin_N PF03954.9 CAM70531.1 - 0.31 10.4 0.3 5.4 6.4 0.0 2.3 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain TRAM_LAG1_CLN8 PF03798.11 CAM70532.1 - 2.3e-37 128.4 12.9 2.3e-37 128.4 9.0 2.2 2 0 0 2 2 2 1 TLC domain Pkinase PF00069.20 CAM70534.1 - 2e-16 59.9 0.0 3.5e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM70534.1 - 1.3e-08 34.3 0.0 4.8e-08 32.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase HAMP PF00672.20 CAM70534.1 - 1.2e-05 25.3 0.1 5.4e-05 23.2 0.1 2.2 1 0 0 1 1 1 1 HAMP domain SNF PF00209.13 CAM70534.1 - 0.013 13.9 0.5 0.02 13.4 0.3 1.1 1 0 0 1 1 1 0 Sodium:neurotransmitter symporter family Pkinase PF00069.20 CAM70535.1 - 8.8e-13 47.9 0.0 2.4e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM70535.1 - 5.1e-11 42.1 0.0 3.2e-10 39.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 CAM70535.1 - 0.3 9.8 0.1 0.71 8.6 0.0 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 DUF912 PF06024.7 CAM70537.1 - 0.045 13.8 0.0 0.084 12.9 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) M20_dimer PF07687.9 CAM70539.1 - 2e-07 30.7 0.0 2.8e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase dimerisation domain Aa_trans PF01490.13 CAM70541.2 - 1.2e-42 145.8 18.2 1.6e-42 145.4 12.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CAM70541.2 - 3.3e-08 32.7 9.8 3.3e-08 32.7 6.8 2.4 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family AA_permease_2 PF13520.1 CAM70541.2 - 1.3e-06 27.2 25.3 1.3e-06 27.2 17.6 2.1 2 0 0 2 2 2 1 Amino acid permease Glycos_transf_1 PF00534.15 CAM70542.1 - 2.4e-16 59.6 0.0 1.6e-15 56.9 0.0 2.1 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CAM70542.1 - 4.2e-10 39.8 0.6 2e-09 37.7 0.4 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CAM70542.1 - 1.3e-05 25.3 0.0 3.3e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_90 PF05686.7 CAM70542.1 - 0.0033 16.1 0.1 0.0071 15.0 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferase family 90 Glyco_trans_4_4 PF13579.1 CAM70542.1 - 0.0095 16.0 0.1 0.0095 16.0 0.1 3.7 3 1 1 4 4 4 1 Glycosyl transferase 4-like domain RINGv PF12906.2 CAM70544.1 - 1.1e-11 44.5 6.2 3.1e-11 43.1 4.3 1.8 1 0 0 1 1 1 1 RING-variant domain DUF4131 PF13567.1 CAM70544.1 - 0.74 9.1 5.9 4.1 6.7 0.7 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Dus PF01207.12 CAM70545.1 - 2.7e-49 167.6 0.2 2.5e-20 72.5 0.0 4.2 3 1 1 4 4 4 4 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 CAM70545.1 - 0.054 12.4 0.0 0.13 11.2 0.0 1.5 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase PAP1 PF08601.5 CAM70547.1 - 9.8 5.7 7.2 0.7 9.5 1.6 1.5 2 0 0 2 2 2 0 Transcription factor PAP1 Thioredoxin_8 PF13905.1 CAM70548.1 - 1.2e-23 82.9 0.0 1.8e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.15 CAM70548.1 - 4.2e-10 39.2 0.0 9e-08 31.7 0.0 2.1 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 CAM70548.1 - 2.1e-08 34.3 0.0 2.9e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 CAM70548.1 - 3.7e-08 33.0 0.0 4.9e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 CAM70548.1 - 8e-07 28.7 0.0 1.1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 CAM70548.1 - 0.00024 20.6 0.1 0.00056 19.4 0.0 1.5 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_7 PF13899.1 CAM70548.1 - 0.00048 20.0 0.0 0.00076 19.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.1 CAM70548.1 - 0.00057 19.4 0.0 0.001 18.6 0.0 1.4 2 0 0 2 2 2 1 F plasmid transfer operon protein Glutaredoxin PF00462.19 CAM70548.1 - 0.02 14.8 0.4 0.25 11.3 0.1 2.2 2 0 0 2 2 2 0 Glutaredoxin Thioredoxin_8 PF13905.1 CAM70549.1 - 1.8e-06 27.9 0.0 3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like CP12 PF02672.10 CAM70550.1 - 0.022 15.2 0.6 0.026 14.9 0.4 1.2 1 0 0 1 1 1 0 CP12 domain Peptidase_M8 PF01457.11 CAM70552.1 - 1.1e-123 413.4 0.0 2.2e-123 412.3 0.0 1.4 1 1 0 1 1 1 1 Leishmanolysin Glycos_transf_1 PF00534.15 CAM70555.1 - 7.4e-16 58.0 0.0 3.2e-15 55.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CAM70555.1 - 5.7e-10 39.4 0.5 2.2e-09 37.5 0.4 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CAM70555.1 - 2.6e-05 24.3 0.0 6.9e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_90 PF05686.7 CAM70555.1 - 0.0064 15.2 0.0 0.013 14.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 90 Peptidase_M20 PF01546.23 CAM70556.1 - 2e-20 73.1 0.6 4e-20 72.1 0.4 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CAM70556.1 - 4.2e-12 45.8 0.0 7.9e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Cpl-7 PF08230.6 CAM70558.1 - 0.17 11.5 0.4 15 5.4 0.0 2.3 2 0 0 2 2 2 0 Cpl-7 lysozyme C-terminal domain CRAL_TRIO PF00650.15 CAM70559.1 - 1.6e-50 170.7 0.0 2.3e-50 170.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 CAM70559.1 - 4.9e-05 23.2 0.0 0.0031 17.4 0.0 2.2 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CAM70559.1 - 0.082 13.0 0.2 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain YopR_core PF09025.5 CAM70559.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 YopR Core CRAL_TRIO PF00650.15 CAM70560.1 - 4.1e-46 156.3 0.0 7.2e-46 155.5 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 CAM70560.1 - 0.043 13.7 0.0 0.12 12.3 0.0 1.8 1 1 0 1 1 1 0 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 CAM70561.1 - 1.9e-38 131.4 0.0 3.3e-38 130.6 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 CAM70561.1 - 0.0098 15.8 0.0 0.062 13.2 0.0 2.1 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain CorA PF01544.13 CAM70563.1 - 8.6e-07 28.2 3.7 6e-05 22.2 1.1 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein tRNA_lig_CPD PF08302.6 CAM70569.1 - 2.2e-07 30.3 0.1 1.2e-05 24.6 0.0 2.4 2 0 0 2 2 2 1 Fungal tRNA ligase phosphodiesterase domain AAA_33 PF13671.1 CAM70569.1 - 9.3e-06 25.5 0.0 4.1e-05 23.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain tRNA_lig_kinase PF08303.6 CAM70569.1 - 0.0003 20.7 0.0 0.0043 16.9 0.0 2.2 1 1 0 1 1 1 1 tRNA ligase kinase domain ABC_tran PF00005.22 CAM70569.1 - 0.0031 17.8 0.0 0.009 16.3 0.0 1.7 2 0 0 2 2 1 1 ABC transporter AAA_17 PF13207.1 CAM70569.1 - 0.0034 18.1 0.0 0.02 15.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CAM70569.1 - 0.0056 16.6 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.1 CAM70569.1 - 0.0063 16.4 0.5 0.1 12.5 0.0 3.2 5 0 0 5 5 5 1 AAA domain ATP_bind_1 PF03029.12 CAM70569.1 - 0.009 15.5 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_29 PF13555.1 CAM70569.1 - 0.02 14.4 0.0 0.091 12.2 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain MobB PF03205.9 CAM70569.1 - 0.032 13.9 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_21 PF13304.1 CAM70569.1 - 0.043 13.7 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 CAM70569.1 - 0.32 11.2 0.0 0.73 10.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Gly-rich_Ago1 PF12764.2 CAM70569.1 - 7.7 7.2 10.5 3.9 8.1 4.7 2.4 3 0 0 3 3 2 0 Glycine-rich region of argonaut Aldo_ket_red PF00248.16 CAM70571.1 - 3.5e-55 186.8 0.1 4e-55 186.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1500 PF07389.7 CAM70571.1 - 0.15 12.0 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1500) Fimbrial_K88 PF02432.10 CAM70574.1 - 0.035 13.5 0.1 0.067 12.6 0.1 1.4 1 0 0 1 1 1 0 Fimbrial, major and minor subunit Ctr PF04145.10 CAM70574.1 - 1.9 8.5 4.8 1.9 8.5 0.3 2.8 2 0 0 2 2 2 0 Ctr copper transporter family ECH PF00378.15 CAM70585.1 - 5.9e-47 159.8 0.0 7.5e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 CAM70585.1 - 0.061 13.1 0.3 0.64 9.7 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 Peptidase_M1 PF01433.15 CAM70586.1 - 5.8e-18 65.1 0.0 5.7e-09 35.5 0.0 2.1 2 0 0 2 2 2 2 Peptidase family M1 Peptidase_MA_2 PF13485.1 CAM70586.1 - 1.4e-06 28.3 0.0 2.6e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily DUF3633 PF12315.3 CAM70586.1 - 0.0026 17.1 0.0 0.0047 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3633) EGF_2 PF07974.8 CAM70589.1 - 0.011 15.8 16.0 0.011 15.8 11.1 5.9 6 2 0 6 6 6 0 EGF-like domain PEMT PF04191.8 CAM70613.1 - 1.1e-29 102.6 1.6 1.1e-29 102.6 1.1 1.6 2 0 0 2 2 2 1 Phospholipid methyltransferase Flavi_NS4A PF01350.12 CAM70613.1 - 0.032 13.7 0.3 0.06 12.9 0.1 1.5 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A S1-P1_nuclease PF02265.11 CAM70615.1 - 3.5e-60 203.7 0.0 5.2e-60 203.1 0.0 1.2 1 0 0 1 1 1 1 S1/P1 Nuclease Zn_dep_PLPC PF00882.13 CAM70615.1 - 0.032 13.8 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 Zinc dependent phospholipase C LRR19-TM PF15176.1 CAM70615.1 - 0.037 13.7 0.2 0.071 12.8 0.2 1.5 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain TM_helix PF05552.7 CAM70615.1 - 1.6 8.4 5.6 14 5.4 2.5 2.4 2 0 0 2 2 2 0 Conserved TM helix SNF2_N PF00176.18 CAM70616.1 - 3.8e-47 160.5 0.0 7.6e-47 159.5 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CAM70616.1 - 1.9e-09 37.2 0.0 1.4e-08 34.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAM70616.1 - 4.5e-06 26.6 0.0 3.3e-05 23.7 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 CAM70616.1 - 0.0011 17.8 0.1 0.054 12.3 0.0 2.5 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.1 CAM70616.1 - 0.0034 17.5 0.3 0.03 14.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain ECH PF00378.15 CAM70617.1 - 4.5e-45 153.6 0.0 5.7e-45 153.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 CAM70617.1 - 0.053 13.2 0.3 0.65 9.7 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 Hydrolase_6 PF13344.1 CAM70618.1 - 3e-20 71.9 0.0 1.1e-19 70.2 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CAM70618.1 - 7e-17 60.9 0.0 2.1e-16 59.3 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 CAM70618.1 - 1.2e-06 29.0 0.0 0.0078 16.6 0.0 2.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CAM70618.1 - 5.1e-05 23.5 0.0 0.027 14.6 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 CAM70618.1 - 0.0001 21.6 0.0 0.00031 20.1 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase Hydrolase_6 PF13344.1 CAM70619.1 - 2e-13 50.1 0.0 5.3e-13 48.7 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CAM70619.1 - 2.7e-10 39.7 0.0 5.3e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CAM70619.1 - 4.3e-05 24.0 0.0 0.0003 21.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 CAM70619.1 - 0.072 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase Symplekin_C PF12295.3 CAM70620.1 - 2.4e-10 40.6 0.2 2.7e-08 33.9 0.0 2.9 2 0 0 2 2 2 2 Symplekin tight junction protein C terminal WD40 PF00400.27 CAM70622.1 - 8.2e-09 35.0 0.6 0.098 12.5 0.0 4.2 3 0 0 3 3 3 3 WD domain, G-beta repeat DUF4189 PF13827.1 CAM70622.1 - 2 8.7 7.9 0.53 10.5 0.6 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4189) SRP-alpha_N PF04086.8 CAM70623.1 - 2.3 7.5 6.0 3.9 6.7 4.1 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Cation_efflux PF01545.16 CAM70624.1 - 6e-55 186.3 13.2 8.3e-55 185.8 9.1 1.2 1 0 0 1 1 1 1 Cation efflux family Barttin PF15462.1 CAM70626.1 - 0.0048 16.5 0.9 0.0066 16.1 0.2 1.5 2 0 0 2 2 2 1 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Toxin_32 PF08120.6 CAM70626.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Tamulustoxin family ER-remodelling PF14755.1 CAM70629.1 - 0.0023 18.0 0.1 0.0039 17.2 0.1 1.3 1 0 0 1 1 1 1 Intracellular membrane remodeller Lipase_3 PF01764.20 CAM70631.1 - 3.4e-37 127.1 0.0 6.2e-37 126.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 CAM70631.1 - 0.00045 19.6 0.4 0.004 16.5 0.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 CAM70631.1 - 0.029 14.1 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PRK PF00485.13 CAM70633.1 - 9.1e-15 54.7 0.0 1e-14 54.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Fer2 PF00111.22 CAM70634.1 - 5.3e-11 42.1 1.2 7.1e-11 41.7 0.8 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.22 CAM70635.1 - 4.2e-09 36.0 2.5 6e-09 35.5 1.7 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NifU PF01106.12 CAM70635.1 - 0.069 12.9 0.5 0.14 11.9 0.3 1.6 1 0 0 1 1 1 0 NifU-like domain Fer2 PF00111.22 CAM70636.1 - 1.2e-09 37.7 1.4 1.6e-09 37.3 0.9 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.22 CAM70637.1 - 4.8e-08 32.6 1.1 7.8e-08 31.9 0.8 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain XkdW PF09636.5 CAM70640.1 - 0.18 11.6 0.0 0.52 10.1 0.0 1.7 1 0 0 1 1 1 0 XkdW protein DUF1699 PF08004.6 CAM70641.1 - 0.28 10.7 0.0 0.77 9.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1699) Pex14_N PF04695.8 CAM70641.1 - 0.69 9.9 0.0 0.69 9.9 0.0 4.4 5 1 0 5 5 5 0 Peroxisomal membrane anchor protein (Pex14p) conserved region UCR_hinge PF02320.11 CAM70642.1 - 2.8e-22 78.4 3.6 3.1e-22 78.2 2.5 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Leucyl-specific PF14795.1 CAM70642.1 - 0.049 13.4 0.0 0.074 12.9 0.0 1.2 1 0 0 1 1 1 0 Leucine-tRNA synthetase-specific domain TerD PF02342.13 CAM70643.1 - 7.6e-78 260.1 0.0 1.4e-56 190.8 0.0 2.3 2 0 0 2 2 2 2 TerD domain Calreticulin PF00262.13 CAM70644.1 - 9e-105 350.3 7.4 1.2e-104 349.8 5.1 1.1 1 0 0 1 1 1 1 Calreticulin family RNA_pol_Rpb1_5 PF04998.12 CAM70645.1 - 1.6e-104 349.0 0.3 2.9e-104 348.2 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 CAM70645.1 - 2e-95 319.9 0.4 1e-94 317.5 0.0 2.3 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 CAM70645.1 - 2e-65 219.7 0.3 5.9e-65 218.2 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 CAM70645.1 - 8.5e-45 152.7 0.8 1.7e-44 151.8 0.6 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 CAM70645.1 - 1e-39 135.7 0.0 2.7e-39 134.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 CAM70645.1 - 4e-29 100.5 0.1 1.3e-28 98.8 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_7 PF04990.7 CAM70645.1 - 2.8e-27 95.0 0.8 8.6e-27 93.4 0.6 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 PspA_IM30 PF04012.7 CAM70645.1 - 0.024 13.9 1.9 0.066 12.5 1.3 1.6 1 0 0 1 1 1 0 PspA/IM30 family CRCB PF02537.10 CAM70646.1 - 1.4e-36 124.9 14.2 3.6e-18 65.5 4.2 2.4 2 0 0 2 2 2 2 CrcB-like protein Metallophos PF00149.23 CAM70647.1 - 5.5e-43 146.6 0.7 6.9e-43 146.3 0.5 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pyr_redox_2 PF07992.9 CAM70648.1 - 8.3e-16 58.4 0.0 2e-15 57.2 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 CAM70648.1 - 1.3e-15 57.3 0.2 7e-15 55.0 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 CAM70648.1 - 2.2e-15 56.8 0.0 8.7e-15 54.8 0.0 2.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CAM70648.1 - 3.8e-07 29.3 0.7 0.072 11.9 0.0 3.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CAM70648.1 - 2.6e-06 27.6 0.5 0.038 14.0 0.2 3.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 CAM70648.1 - 3.4e-05 23.6 0.0 0.00015 21.5 0.0 2.0 2 0 0 2 2 2 1 ThiF family 3HCDH_N PF02737.13 CAM70648.1 - 5e-05 23.0 0.1 9e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K_oxygenase PF13434.1 CAM70648.1 - 5.3e-05 22.3 0.0 0.00031 19.7 0.0 1.9 1 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 CAM70648.1 - 0.0043 15.9 0.0 0.19 10.5 0.0 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A ApbA PF02558.11 CAM70648.1 - 0.013 14.9 0.0 0.044 13.2 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 CAM70648.1 - 0.014 15.3 0.0 0.039 13.9 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.9 CAM70648.1 - 0.024 13.1 0.4 0.51 8.7 0.1 2.3 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.19 CAM70648.1 - 0.034 12.9 1.2 1.1 8.0 0.1 2.5 3 0 0 3 3 3 0 FAD binding domain Shikimate_DH PF01488.15 CAM70648.1 - 0.044 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase BTD PF09270.5 CAM70648.1 - 0.11 12.1 0.0 0.43 10.3 0.0 1.8 2 0 0 2 2 2 0 Beta-trefoil DNA-binding domain NAD_binding_9 PF13454.1 CAM70648.1 - 0.15 11.8 0.1 26 4.5 0.0 2.7 2 1 0 2 2 2 0 FAD-NAD(P)-binding Mucin PF01456.12 CAM70652.1 - 6.5e-05 22.7 60.7 6.5e-05 22.7 42.0 5.1 2 1 2 4 4 4 1 Mucin-like glycoprotein IncA PF04156.9 CAM70652.1 - 0.17 11.4 1.1 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 IncA protein LRR_4 PF12799.2 CAM70653.1 - 0.056 13.0 0.9 0.12 11.9 0.6 1.6 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) WHIM1 PF15612.1 CAM70653.1 - 0.17 11.9 1.2 0.35 10.8 0.1 2.1 2 0 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 1 PPR PF01535.15 CAM70654.1 - 0.28 11.2 0.1 2.6 8.2 0.1 2.5 2 0 0 2 2 2 0 PPR repeat DNA_pol_A_exo1 PF01612.15 CAM70655.1 - 4.6e-06 26.2 0.1 2.1e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 3'-5' exonuclease MORN PF02493.15 CAM70656.1 - 5.6e-30 101.2 45.6 5.8e-09 35.1 0.5 7.9 8 0 0 8 8 8 7 MORN repeat Kinesin PF00225.18 CAM70656.1 - 3.3e-18 65.4 0.1 1.5e-17 63.3 0.0 2.0 2 1 0 2 2 2 1 Kinesin motor domain PEPcase_2 PF14010.1 CAM70656.1 - 0.023 13.0 2.5 0.059 11.6 0.1 2.2 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxylase Reo_sigmaC PF04582.7 CAM70656.1 - 1.3 8.1 8.9 0.25 10.4 0.9 3.2 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Bap31 PF05529.7 CAM70657.1 - 0.0033 16.9 3.6 0.0044 16.5 2.5 1.3 1 1 0 1 1 1 1 B-cell receptor-associated protein 31-like DUF1077 PF06417.7 CAM70657.1 - 0.32 10.3 2.4 1.1 8.5 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1077) FtsL PF04999.8 CAM70657.1 - 5.3 6.8 5.5 2 8.1 0.1 2.5 1 1 2 3 3 3 0 Cell division protein FtsL RCC1 PF00415.13 CAM70658.1 - 7.4e-24 83.7 10.0 3.4e-11 43.1 0.0 7.7 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CAM70658.1 - 4e-19 67.6 17.8 3.6e-05 23.2 1.9 5.5 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat EMP24_GP25L PF01105.19 CAM70659.1 - 1e-31 110.0 0.0 1.4e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD COPIIcoated_ERV PF07970.7 CAM70660.1 - 1.3e-66 224.4 0.0 1.9e-66 223.8 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CAM70660.1 - 4.1e-30 103.6 0.2 9.5e-30 102.4 0.1 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Cytochrom_B561 PF03188.11 CAM70660.1 - 0.1 12.4 0.1 0.1 12.4 0.0 1.9 2 1 0 2 2 2 0 Eukaryotic cytochrome b561 RRM_1 PF00076.17 CAM70663.1 - 1.7e-11 43.5 0.0 3.3e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM70663.1 - 0.0015 18.4 0.0 0.0031 17.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM70663.1 - 0.0015 18.3 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1843 PF08898.5 CAM70663.1 - 0.11 12.5 0.0 1 9.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Arf PF00025.16 CAM70666.1 - 1.1e-77 259.1 0.1 1.2e-77 259.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CAM70666.1 - 4.6e-14 52.0 0.0 5.6e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CAM70666.1 - 8e-13 48.0 0.0 8.6e-13 47.9 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CAM70666.1 - 2.2e-12 46.3 0.4 7.9e-09 34.6 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CAM70666.1 - 1.1e-09 37.7 0.0 1.3e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CAM70666.1 - 5.7e-08 33.2 0.0 7.7e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CAM70666.1 - 7.4e-05 22.6 0.0 9.8e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 CAM70666.1 - 0.0061 15.6 0.1 0.0081 15.2 0.1 1.3 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 CAM70666.1 - 0.02 14.7 0.1 0.035 13.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 CAM70666.1 - 0.022 14.1 0.1 0.26 10.7 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain cobW PF02492.14 CAM70666.1 - 0.091 12.1 0.1 0.7 9.3 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 CAM70666.1 - 0.18 11.6 0.4 6.1 6.7 0.0 2.1 1 1 1 2 2 2 0 AAA domain DUF1771 PF08590.5 CAM70668.1 - 1.1e-20 73.4 6.4 1.1e-20 73.4 4.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 CAM70668.1 - 3.5e-12 46.3 0.6 1.4e-11 44.4 0.0 2.3 3 0 0 3 3 3 1 Smr domain KH_1 PF00013.24 CAM70668.1 - 2e-09 36.9 0.9 3.3e-09 36.2 0.6 1.4 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 CAM70668.1 - 1.1e-05 24.9 0.2 2.2e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 KH domain KH_2 PF07650.12 CAM70668.1 - 0.0015 18.0 0.8 0.01 15.3 0.2 2.4 2 0 0 2 2 2 1 KH domain Sec2p PF06428.6 CAM70668.1 - 2.4 8.0 6.0 28 4.6 3.2 2.6 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p Maf1 PF09174.5 CAM70669.1 - 2.3e-44 151.3 0.0 2.8e-44 151.1 0.0 1.1 1 0 0 1 1 1 1 Maf1 regulator Tryp_alpha_amyl PF00234.17 CAM70669.1 - 0.025 14.8 0.0 0.04 14.1 0.0 1.3 1 0 0 1 1 1 0 Protease inhibitor/seed storage/LTP family GILT PF03227.11 CAM70669.1 - 0.069 13.0 0.6 4.8 7.0 0.0 2.2 2 0 0 2 2 2 0 Gamma interferon inducible lysosomal thiol reductase (GILT) HD_assoc PF13286.1 CAM70670.1 - 0.082 13.1 0.1 0.19 11.9 0.1 1.6 1 0 0 1 1 1 0 Phosphohydrolase-associated domain DUF1049 PF06305.6 CAM70671.1 - 0.091 12.2 0.3 0.28 10.6 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF948 PF06103.6 CAM70671.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF4234 PF14018.1 CAM70671.1 - 0.19 11.4 1.2 2.1 8.1 0.0 2.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4234) DUF2244 PF10003.4 CAM70671.1 - 2.6 7.4 9.6 0.072 12.4 0.3 2.7 3 0 0 3 3 3 0 Integral membrane protein (DUF2244) Ribosomal_L12 PF00542.14 CAM70672.1 - 1.2e-17 63.6 1.4 2.2e-17 62.7 1.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain PYRIN PF02758.11 CAM70672.1 - 0.095 12.4 0.0 0.42 10.3 0.0 2.0 2 0 0 2 2 2 0 PAAD/DAPIN/Pyrin domain Pkinase PF00069.20 CAM70673.1 - 5.8e-56 189.5 0.0 1.6e-55 188.0 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM70673.1 - 2.2e-29 102.3 0.0 4.6e-29 101.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 CAM70673.1 - 0.016 14.5 1.6 0.027 13.8 0.1 2.1 2 1 0 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.6 CAM70673.1 - 0.029 13.1 0.1 0.046 12.5 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase L71 PF02448.10 CAM70673.1 - 0.04 13.7 0.1 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 L71 family Spc7 PF08317.6 CAM70673.1 - 3.1 6.3 10.4 0.056 12.0 0.2 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.10 CAM70673.1 - 5.5 6.0 10.9 40 3.2 7.5 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit Bap31 PF05529.7 CAM70673.1 - 5.8 6.3 6.8 13 5.1 0.1 2.3 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like DivIC PF04977.10 CAM70673.1 - 7.5 6.1 11.8 1.2 8.6 0.0 3.3 3 0 0 3 3 3 0 Septum formation initiator DUF4556 PF15094.1 CAM70674.1 - 0.057 12.9 0.1 0.086 12.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4556) Aldo_ket_red PF00248.16 CAM70675.1 - 1e-64 218.1 0.0 1.2e-64 217.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HAD_2 PF13419.1 CAM70675.1 - 0.029 14.5 0.0 0.046 13.9 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase PSII PF00421.14 CAM70675.1 - 0.1 11.2 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Photosystem II protein Clathrin PF00637.15 CAM70676.1 - 1.8e-08 34.0 0.8 1.8e-08 34.0 0.6 2.1 3 0 0 3 3 3 1 Region in Clathrin and VPS RNA_pol_Rpb4 PF03874.11 CAM70676.1 - 0.073 13.0 0.1 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb4 VPS11_C PF12451.3 CAM70676.1 - 0.1 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal zf-RING_2 PF13639.1 CAM70676.1 - 4 7.3 12.6 4.2 7.2 7.0 2.5 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.1 CAM70676.1 - 4.4 7.1 14.8 2.3 7.9 7.0 2.7 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CAM70676.1 - 9.5 6.3 12.7 2.3 8.2 5.6 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Nup54 PF13874.1 CAM70677.1 - 2.9e-41 140.4 0.5 2.9e-41 140.4 0.4 2.3 2 1 1 3 3 3 1 Nucleoporin complex subunit 54 DUF4588 PF15251.1 CAM70679.1 - 0.002 18.1 0.2 0.002 18.1 0.1 2.2 2 1 1 3 3 3 1 Domain of unknown function (DUF4588) Hairy_orange PF07527.8 CAM70679.1 - 0.032 13.9 0.1 0.072 12.8 0.1 1.7 1 1 0 1 1 1 0 Hairy Orange Inositol_P PF00459.20 CAM70680.1 - 2.1e-14 53.4 0.8 3.8e-13 49.3 0.6 2.0 1 1 0 1 1 1 1 Inositol monophosphatase family Ribosomal_L7Ae PF01248.21 CAM70681.1 - 0.093 12.2 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SQS_PSY PF00494.14 CAM70682.1 - 1.6e-44 152.1 0.0 2.5e-44 151.5 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase NUDIX PF00293.23 CAM70683.1 - 1.7e-13 50.3 0.0 2.7e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.6 CAM70683.1 - 2e-09 36.7 3.6 3.9e-09 35.8 2.5 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain DZR PF12773.2 CAM70683.1 - 0.0024 17.6 0.7 0.0049 16.6 0.5 1.5 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.1 CAM70683.1 - 0.29 10.6 4.2 1.7 8.2 0.4 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 CAM70683.1 - 0.76 9.0 6.5 0.37 10.0 0.7 2.0 1 1 0 2 2 2 0 zinc-ribbon domain UPF0547 PF10571.4 CAM70683.1 - 2.4 7.9 4.7 7.5 6.3 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Pkinase PF00069.20 CAM70684.1 - 2e-62 210.6 0.0 2.7e-62 210.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM70684.1 - 4.3e-43 147.2 0.0 6.7e-43 146.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM70684.1 - 5.5e-09 35.4 0.0 3.4e-07 29.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like PH PF00169.24 CAM70684.1 - 0.00012 22.1 0.0 0.00023 21.3 0.0 1.4 1 0 0 1 1 1 1 PH domain DUF1636 PF07845.6 CAM70684.1 - 0.041 14.1 0.4 0.1 12.8 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1636) Carboxyl_trans PF01039.17 CAM70685.1 - 2.6e-127 425.2 0.0 3.6e-127 424.6 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain ACC_central PF08326.7 CAM70685.1 - 1.7e-121 406.6 0.0 3.2e-114 382.5 0.1 2.1 1 1 1 2 2 2 2 Acetyl-CoA carboxylase, central region CPSase_L_D2 PF02786.12 CAM70685.1 - 8.3e-49 165.7 0.0 1.6e-48 164.8 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CAM70685.1 - 5.8e-25 87.5 0.0 1.4e-24 86.3 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CAM70685.1 - 2.8e-21 75.5 0.0 2e-20 72.7 0.0 2.5 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 CAM70685.1 - 6.7e-11 42.2 0.0 1.5e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CAM70685.1 - 1.3e-10 40.5 0.0 9.5e-09 34.4 0.0 3.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 CAM70685.1 - 3.3e-07 29.8 0.0 9.7e-07 28.3 0.0 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 CAM70685.1 - 0.00014 21.3 0.0 0.0003 20.2 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 CAM70685.1 - 0.00077 18.8 0.0 0.0022 17.3 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 CAM70685.1 - 0.052 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_ST PF14397.1 CAM70685.1 - 0.22 10.6 0.0 0.42 9.6 0.0 1.4 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp SMK-1 PF04802.10 CAM70686.1 - 1.2e-05 24.8 0.0 2.3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 TilS PF09179.6 CAM70686.1 - 0.034 14.1 0.4 0.098 12.6 0.0 1.9 2 0 0 2 2 2 0 TilS substrate binding domain DivIC PF04977.10 CAM70688.1 - 0.041 13.3 7.3 18 4.9 0.0 4.3 3 1 1 4 4 4 0 Septum formation initiator ERM PF00769.14 CAM70688.1 - 0.068 12.6 23.9 0.065 12.7 4.1 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family HALZ PF02183.13 CAM70688.1 - 0.091 12.4 10.3 1.7 8.4 0.6 4.2 4 1 1 5 5 5 0 Homeobox associated leucine zipper Spc7 PF08317.6 CAM70688.1 - 0.14 10.8 8.2 0.072 11.7 3.2 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.3 CAM70688.1 - 2.6 7.7 25.7 0.14 11.9 2.6 4.1 3 2 2 5 5 5 0 TATA element modulatory factor 1 TATA binding APG6 PF04111.7 CAM70688.1 - 4.4 6.2 15.0 0.69 8.8 1.7 2.6 1 1 1 2 2 2 0 Autophagy protein Apg6 ADIP PF11559.3 CAM70688.1 - 6.2 6.7 13.2 3.8 7.3 6.0 2.8 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 CAM70688.1 - 6.5 7.1 11.2 1.4 9.2 2.4 3.1 2 2 2 4 4 4 0 Protein of unknown function (DUF972) Ax_dynein_light PF10211.4 CAM70689.1 - 0.013 15.3 8.3 0.013 15.3 5.7 2.5 1 1 0 2 2 2 0 Axonemal dynein light chain Flp_C PF05202.7 CAM70689.1 - 0.092 11.9 0.3 2.4 7.2 0.1 2.1 2 0 0 2 2 2 0 Recombinase Flp protein Spc7 PF08317.6 CAM70689.1 - 0.83 8.2 10.7 0.15 10.6 4.1 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein CENP-H PF05837.7 CAM70689.1 - 0.93 9.6 10.3 0.65 10.2 4.4 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF342 PF03961.8 CAM70689.1 - 1 7.6 5.0 1.5 7.1 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Syntaxin-6_N PF09177.6 CAM70689.1 - 3.9 7.9 12.5 0.68 10.3 4.1 2.9 3 1 1 4 4 4 0 Syntaxin 6, N-terminal Transposase_22 PF02994.9 CAM70693.1 - 0.0061 15.1 0.1 0.009 14.5 0.1 1.2 1 0 0 1 1 1 1 L1 transposable element Per1 PF04080.8 CAM70693.1 - 0.011 15.1 0.1 0.014 14.8 0.1 1.1 1 0 0 1 1 1 0 Per1-like YlbD_coat PF14071.1 CAM70693.1 - 0.058 13.4 0.4 4.7 7.2 0.0 2.3 2 0 0 2 2 2 0 Putative coat protein DUF948 PF06103.6 CAM70693.1 - 0.084 12.7 2.0 0.22 11.4 1.4 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF1515 PF07439.6 CAM70693.1 - 0.28 11.0 6.1 0.54 10.0 2.4 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) Phg_2220_C PF09524.5 CAM70693.1 - 0.94 9.5 4.8 2.8 8.0 0.2 2.3 1 1 1 2 2 2 0 Conserved phage C-terminus (Phg_2220_C) Cyclase PF04199.8 CAM70694.1 - 5.3e-19 68.5 0.0 7e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Zip PF02535.17 CAM70695.2 - 2.4e-39 135.2 7.8 2.8e-39 134.9 5.4 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Zip PF02535.17 CAM70697.2 - 2.4e-39 135.2 7.8 2.8e-39 134.9 5.4 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter BTB_2 PF02214.17 CAM70698.1 - 4.9e-05 23.4 0.0 0.00013 22.0 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain SPRY PF00622.23 CAM70698.1 - 0.0005 20.1 0.0 0.037 14.1 0.0 2.3 1 1 1 2 2 2 2 SPRY domain Peptidase_M16 PF00675.15 CAM70699.1 - 1.3e-31 109.3 0.0 2.5e-31 108.4 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CAM70699.1 - 1.7e-11 44.1 0.0 1.3e-06 28.2 0.0 2.8 2 0 0 2 2 2 2 Peptidase M16 inactive domain DnaJ PF00226.26 CAM70700.1 - 4.1e-19 68.0 0.2 7.3e-19 67.2 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Lzipper-MIP1 PF14389.1 CAM70702.1 - 0.014 15.4 0.4 0.014 15.4 0.3 9.3 6 4 4 10 10 10 0 Leucine-zipper of ternary complex factor MIP1 Corona_M PF01635.13 CAM70702.1 - 0.12 11.3 0.0 0.21 10.5 0.0 1.4 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein Erp_C PF06780.6 CAM70702.1 - 0.25 11.1 17.9 0.5 10.1 2.3 3.8 3 0 0 3 3 3 0 Erp protein C-terminus PEMT PF04191.8 CAM70703.1 - 3.5e-49 165.3 11.9 3.4e-28 97.8 0.8 2.9 2 0 0 2 2 2 2 Phospholipid methyltransferase CPSase_L_D2 PF02786.12 CAM70704.1 - 1.5e-63 213.9 0.0 2.9e-63 212.9 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CAM70704.1 - 2.2e-41 140.3 0.1 8.3e-41 138.5 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CAM70704.1 - 1.7e-33 114.7 0.0 4.5e-33 113.4 0.0 1.7 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 CAM70704.1 - 2.9e-16 59.7 0.1 6.4e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 CAM70704.1 - 5.2e-15 54.8 1.8 1e-14 53.8 1.3 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 CAM70704.1 - 3.6e-12 46.1 0.0 1.2e-11 44.3 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 CAM70704.1 - 1.4e-11 43.7 0.0 3.4e-08 32.6 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 CAM70704.1 - 9.2e-10 38.1 0.1 1.6e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 CAM70704.1 - 1.1e-05 25.0 0.1 5.8e-05 22.6 0.0 2.1 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_2 PF12700.2 CAM70704.1 - 1.9e-05 23.9 0.1 0.013 14.7 0.1 2.2 1 1 1 2 2 2 2 HlyD family secretion protein RimK PF08443.6 CAM70704.1 - 0.0002 20.9 0.0 0.27 10.6 0.0 2.3 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 CAM70704.1 - 0.0042 16.9 0.0 0.011 15.5 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 CAM70704.1 - 0.049 13.9 0.2 12 6.3 0.0 2.9 3 0 0 3 3 3 0 HlyD family secretion protein RnfC_N PF13375.1 CAM70704.1 - 0.16 11.7 1.1 0.54 10.0 0.3 2.2 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain HlyD PF00529.15 CAM70704.1 - 0.19 10.9 0.0 0.37 10.0 0.0 1.4 1 1 0 1 1 1 0 HlyD family secretion protein Robl_LC7 PF03259.12 CAM70706.1 - 2.5e-07 30.1 0.0 3.7e-07 29.6 0.0 1.3 1 1 0 1 1 1 1 Roadblock/LC7 domain Pol_alpha_B_N PF08418.5 CAM70707.1 - 0.17 11.3 0.2 0.36 10.3 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Pkinase PF00069.20 CAM70708.1 - 1.1e-61 208.3 0.0 1.5e-61 207.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM70708.1 - 9.2e-42 142.8 0.0 1.3e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 CAM70708.1 - 2.1e-10 40.7 0.0 3.5e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 CAM70708.1 - 1.9e-08 33.6 0.0 3.5e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like PH_9 PF15410.1 CAM70708.1 - 1.9e-08 34.4 0.3 5.4e-07 29.7 0.2 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 CAM70708.1 - 0.00013 22.1 1.3 0.037 14.2 0.9 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain MFS_1 PF07690.11 CAM70709.1 - 4.5e-21 74.9 37.8 2.1e-17 62.8 18.1 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 CAM70709.1 - 4.2e-07 29.4 16.9 4.2e-07 29.4 11.7 2.6 2 2 0 2 2 2 1 Nodulin-like Histone PF00125.19 CAM70710.1 - 3.7e-14 52.5 0.8 4.5e-14 52.3 0.6 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CAM70710.1 - 2.6e-05 24.1 0.1 4.3e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 CAM70710.1 - 7.4e-05 22.6 0.1 0.00011 22.0 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.8 CAM70710.1 - 0.00064 19.4 0.0 0.00081 19.0 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 CAM70710.1 - 0.0013 18.5 0.0 0.0014 18.4 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit PCP_red PF08369.5 CAM70710.1 - 0.033 14.0 1.0 0.064 13.1 0.3 1.9 2 1 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit FbpA PF05833.6 CAM70710.1 - 0.049 12.1 0.0 0.057 11.9 0.0 1.0 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF4400 PF14348.1 CAM70710.1 - 0.092 12.1 0.3 0.13 11.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) Galactosyl_T PF01762.16 CAM70711.1 - 0.00013 21.6 0.1 0.00065 19.3 0.0 2.2 3 0 0 3 3 3 1 Galactosyltransferase DUF2205 PF10224.4 CAM70749.1 - 0.3 10.7 12.3 0.78 9.3 0.8 4.1 3 1 0 3 3 3 0 Predicted coiled-coil protein (DUF2205) WXG100 PF06013.7 CAM70749.1 - 2.2 8.3 10.5 0.5 10.4 0.5 4.0 4 0 0 4 4 4 0 Proteins of 100 residues with WXG WD40 PF00400.27 CAM70752.1 - 1.7e-37 125.9 7.7 2.5e-08 33.5 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat SNARE PF05739.14 CAM70754.1 - 1e-13 50.7 8.5 1.2e-13 50.5 1.1 3.1 3 0 0 3 3 3 1 SNARE domain DUF4208 PF13907.1 CAM70754.1 - 0.0088 16.2 2.4 2.8 8.2 0.2 2.5 1 1 0 2 2 2 2 Domain of unknown function (DUF4208) Nup54 PF13874.1 CAM70754.1 - 0.02 14.5 1.4 0.02 14.5 1.0 2.3 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 DUF883 PF05957.8 CAM70754.1 - 0.31 11.4 5.9 0.4 11.1 0.2 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Baculo_PEP_C PF04513.7 CAM70754.1 - 0.44 10.3 6.6 1.9 8.2 0.3 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SF-assemblin PF06705.6 CAM70754.1 - 0.45 9.6 4.8 1.6 7.8 0.2 2.2 1 1 0 2 2 2 0 SF-assemblin/beta giardin DUF3154 PF11351.3 CAM70754.1 - 0.76 9.5 4.0 2.9 7.6 0.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3154) NMT_C PF02799.10 CAM70755.1 - 6.9e-73 244.0 0.5 1.1e-72 243.4 0.1 1.5 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 CAM70755.1 - 1.1e-62 210.4 0.9 2.8e-60 202.6 0.6 2.3 1 1 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain DUF3432 PF11914.3 CAM70756.1 - 0.0098 15.9 3.9 0.0098 15.9 2.7 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3432) NIF PF03031.13 CAM70757.1 - 1.7e-25 89.5 0.0 1.8e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Mito_carr PF00153.22 CAM70758.1 - 8.3e-41 137.6 4.4 2.2e-14 52.9 0.0 4.8 3 2 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.20 CAM70759.1 - 2.9e-59 200.3 0.0 3.8e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM70759.1 - 7.8e-28 97.2 0.0 1.1e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM70759.1 - 0.00023 20.2 0.0 0.00044 19.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CAM70759.1 - 0.0012 17.9 0.0 0.0019 17.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CAM70759.1 - 0.077 12.7 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Skp1 PF01466.14 CAM70760.1 - 0.046 13.7 0.2 0.08 12.9 0.1 1.3 1 0 0 1 1 1 0 Skp1 family, dimerisation domain Arm PF00514.18 CAM70761.1 - 2.2e-40 135.1 26.3 3.7e-07 29.7 0.0 16.3 16 1 0 16 16 16 9 Armadillo/beta-catenin-like repeat Arm_2 PF04826.8 CAM70761.1 - 2.4e-09 36.7 0.9 0.027 13.5 0.0 6.1 4 2 5 9 9 9 2 Armadillo-like HEAT_2 PF13646.1 CAM70761.1 - 6e-06 26.4 9.1 0.2 11.9 0.0 6.5 3 2 2 6 6 6 3 HEAT repeats Atx10homo_assoc PF09759.4 CAM70761.1 - 0.021 14.5 1.3 20 4.9 0.0 4.9 5 0 0 5 5 5 0 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.1 CAM70761.1 - 0.1 13.1 15.6 3.4 8.2 0.1 7.6 7 3 1 8 8 8 0 HEAT-like repeat HEAT PF02985.17 CAM70761.1 - 0.11 12.6 10.0 35 4.8 0.1 6.2 6 1 0 6 6 6 0 HEAT repeat TMF_DNA_bd PF12329.3 CAM70761.1 - 0.52 10.1 7.3 1.3 8.8 5.1 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Utp14 PF04615.8 CAM70762.1 - 6.3e-81 272.6 41.3 6.3e-81 272.6 28.6 2.5 1 1 0 1 1 1 1 Utp14 protein Mit_KHE1 PF10173.4 CAM70762.1 - 0.12 12.2 1.3 0.42 10.4 0.9 1.9 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related LRR_9 PF14580.1 CAM70765.1 - 2.2e-16 59.9 1.5 5.7e-16 58.5 1.0 1.6 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 CAM70765.1 - 0.00021 20.8 0.1 0.31 10.6 0.0 3.4 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) CCDC-167 PF15188.1 CAM70765.1 - 0.005 16.7 3.0 0.005 16.7 2.1 2.2 3 0 0 3 3 3 1 Coiled-coil domain-containing protein 167 K_channel_TID PF07941.6 CAM70765.1 - 0.019 15.1 3.3 0.052 13.7 2.3 1.7 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain GvpG PF05120.7 CAM70765.1 - 0.21 11.4 2.5 0.46 10.3 1.7 1.5 1 0 0 1 1 1 0 Gas vesicle protein G HSP70 PF00012.15 CAM70767.1 - 1.1e-08 33.4 0.1 0.00021 19.3 0.0 2.4 2 0 0 2 2 2 2 Hsp70 protein PKI PF02827.11 CAM70768.1 - 0.009 16.1 0.3 0.035 14.2 0.0 2.1 2 0 0 2 2 2 1 cAMP-dependent protein kinase inhibitor Baculo_PEP_C PF04513.7 CAM70768.1 - 0.056 13.2 5.7 1.9 8.3 0.6 3.3 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Herpes_UL6 PF01763.11 CAM70768.1 - 0.095 10.8 1.8 0.11 10.7 0.5 1.6 1 1 0 1 1 1 0 Herpesvirus UL6 like Filament PF00038.16 CAM70768.1 - 0.17 11.3 10.2 0.061 12.7 3.9 2.5 2 1 0 2 2 2 0 Intermediate filament protein Kinetocho_Slk19 PF12709.2 CAM70768.1 - 0.34 11.0 0.1 0.34 11.0 0.0 3.8 4 1 1 5 5 5 0 Central kinetochore-associated Rtt106 PF08512.7 CAM70769.1 - 3.4e-15 55.8 0.0 4.8e-14 52.0 0.0 2.7 2 0 0 2 2 2 1 Histone chaperone Rttp106-like SSrecog PF03531.9 CAM70769.1 - 1.2e-05 24.8 0.3 0.089 12.1 0.0 2.7 2 1 0 2 2 2 2 Structure-specific recognition protein (SSRP1) CDC45 PF02724.9 CAM70769.1 - 0.24 9.4 26.4 0.32 8.9 18.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 CAM70769.1 - 0.7 7.7 28.4 0.95 7.3 19.7 1.1 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.8 CAM70769.1 - 2.1 7.8 29.9 3 7.3 20.7 1.2 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.7 CAM70769.1 - 3.3 6.9 31.5 4.4 6.4 21.8 1.1 1 0 0 1 1 1 0 SDA1 Herpes_DNAp_acc PF04929.7 CAM70769.1 - 8 5.3 14.3 14 4.5 9.9 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor SOG2 PF10428.4 CAM70770.1 - 0.3 9.6 8.9 0.048 12.3 0.5 2.4 2 1 0 2 2 2 0 RAM signalling pathway protein Dynein_light PF01221.13 CAM70771.1 - 3.4e-43 145.5 0.9 3.9e-43 145.3 0.6 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Peptidase_C3 PF00548.15 CAM70771.1 - 0.00056 19.7 0.1 0.00058 19.7 0.0 1.1 1 0 0 1 1 1 1 3C cysteine protease (picornain 3C) HTH_33 PF13592.1 CAM70771.1 - 0.053 13.0 0.0 0.092 12.2 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix Imm28 PF15574.1 CAM70771.1 - 0.054 13.0 0.1 0.072 12.6 0.1 1.1 1 0 0 1 1 1 0 Immunity protein 28 Ectatomin PF06457.6 CAM70771.1 - 0.055 13.1 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 Ectatomin ECSIT PF06239.6 CAM70771.1 - 0.1 11.4 0.1 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway LRR_6 PF13516.1 CAM70772.1 - 0.0032 17.3 2.9 5.5 7.3 0.0 4.7 4 0 0 4 4 4 1 Leucine Rich repeat LRR_4 PF12799.2 CAM70772.1 - 0.016 14.8 2.5 4.5 7.0 0.0 4.5 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CAM70772.1 - 0.053 13.5 7.3 15 6.0 0.1 4.9 4 0 0 4 4 4 0 Leucine Rich Repeat AAA_13 PF13166.1 CAM70772.1 - 0.21 9.9 1.4 0.32 9.3 1.0 1.2 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 CAM70772.1 - 0.5 9.9 13.2 0.065 12.8 4.5 2.4 2 0 0 2 2 2 0 IncA protein LRR_8 PF13855.1 CAM70772.1 - 0.66 9.7 3.5 37 4.1 0.0 3.7 4 0 0 4 4 4 0 Leucine rich repeat Cluap1 PF10234.4 CAM70772.1 - 1.9 7.6 12.8 0.059 12.5 3.1 2.1 1 1 1 2 2 2 0 Clusterin-associated protein-1 LRR_7 PF13504.1 CAM70772.1 - 6.7 7.3 10.6 14 6.4 0.3 4.6 5 0 0 5 5 5 0 Leucine rich repeat Atg14 PF10186.4 CAM70772.1 - 7.9 5.3 16.6 15 4.4 10.7 1.8 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Pkinase PF00069.20 CAM70774.1 - 7.2e-71 238.3 0.0 1.1e-70 237.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM70774.1 - 8.9e-51 172.4 0.0 1.3e-50 171.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM70774.1 - 2.6e-06 26.6 0.0 5.4e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CAM70774.1 - 0.018 14.4 0.1 0.044 13.1 0.1 1.5 1 0 0 1 1 1 0 RIO1 family B9-C2 PF07162.6 CAM70776.1 - 1e-45 155.5 0.0 1.2e-45 155.2 0.0 1.1 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein COX6A PF02046.10 CAM70777.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIa LRR_4 PF12799.2 CAM70778.1 - 4.4e-17 61.2 5.3 4.3e-05 23.0 0.3 5.4 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM70778.1 - 7.3e-12 44.8 7.4 4e-05 23.2 0.8 4.6 4 1 0 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 CAM70778.1 - 3.1e-08 32.5 10.1 0.038 14.0 0.2 6.7 7 1 0 7 7 7 3 Leucine Rich Repeat LRR_7 PF13504.1 CAM70778.1 - 0.013 15.5 6.7 0.21 11.9 0.1 5.1 5 0 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 CAM70778.1 - 0.043 13.8 2.2 94 3.5 0.2 4.9 4 1 0 4 4 4 0 Leucine Rich repeat TPR_19 PF14559.1 CAM70779.1 - 1.6e-08 34.7 11.1 0.025 14.9 0.2 7.9 7 1 1 8 8 7 2 Tetratricopeptide repeat Clathrin PF00637.15 CAM70779.1 - 2.7e-06 27.0 0.2 3.1 7.3 0.0 5.5 4 2 2 6 6 6 2 Region in Clathrin and VPS Coatomer_WDAD PF04053.9 CAM70779.1 - 3.1e-06 26.2 2.1 0.011 14.5 0.0 4.2 4 1 1 5 5 5 2 Coatomer WD associated region TPR_7 PF13176.1 CAM70779.1 - 9.5e-05 21.9 20.2 0.81 9.6 0.3 8.2 9 1 1 10 10 9 3 Tetratricopeptide repeat TPR_12 PF13424.1 CAM70779.1 - 0.00044 20.1 19.8 1.4 8.8 0.2 8.2 7 1 1 8 8 8 1 Tetratricopeptide repeat Nucleoporin_N PF08801.6 CAM70779.1 - 0.0027 16.5 0.0 0.0051 15.6 0.0 1.4 1 0 0 1 1 1 1 Nup133 N terminal like TPR_14 PF13428.1 CAM70779.1 - 0.0077 16.7 28.8 3.2 8.6 0.7 10.5 8 2 2 10 10 9 1 Tetratricopeptide repeat TPR_16 PF13432.1 CAM70779.1 - 0.044 14.4 28.8 0.25 12.0 1.3 7.6 7 1 0 7 7 7 0 Tetratricopeptide repeat WD40 PF00400.27 CAM70779.1 - 0.14 12.1 1.5 30 4.6 0.0 3.9 4 0 0 4 4 4 0 WD domain, G-beta repeat DUF1199 PF06712.6 CAM70779.1 - 0.19 11.5 0.0 0.59 9.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1199) TPR_1 PF00515.23 CAM70779.1 - 0.24 11.0 18.8 9.7 5.9 2.1 7.0 6 1 0 6 6 6 0 Tetratricopeptide repeat MIT PF04212.13 CAM70779.1 - 0.25 11.2 13.1 13 5.7 0.1 5.3 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.12 CAM70779.1 - 0.39 10.7 32.6 3.5 7.7 2.4 9.8 10 1 0 10 10 10 0 Tetratricopeptide repeat TPR_8 PF13181.1 CAM70779.1 - 2.5 8.0 18.2 2 8.3 0.6 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat RHD3 PF05879.7 CAM70785.1 - 1.2e-101 340.9 0.0 1.3e-89 301.1 0.0 3.2 2 1 0 3 3 3 2 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.18 CAM70785.1 - 2.5e-05 24.1 0.1 4.9e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.1 CAM70785.1 - 0.00044 20.2 0.4 0.0013 18.6 0.1 2.0 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 CAM70785.1 - 0.014 15.8 0.0 0.034 14.6 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein MMR_HSR1 PF01926.18 CAM70785.1 - 0.043 13.7 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF3653 PF12375.3 CAM70786.1 - 9.2 6.5 8.8 8.6 6.6 3.6 2.8 2 1 0 2 2 2 0 Phage protein JAB PF01398.16 CAM70787.1 - 4.2e-22 78.0 0.0 2.9e-21 75.3 0.0 2.1 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 CAM70787.1 - 1.4e-20 73.4 0.2 2.7e-20 72.5 0.1 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function DUF2365 PF10157.4 CAM70787.1 - 0.002 17.9 0.9 0.0037 17.1 0.7 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2365) DEAD PF00270.24 CAM70788.1 - 1.4e-42 145.0 0.0 2.9e-42 144.0 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM70788.1 - 8.3e-27 92.8 0.1 4.5e-26 90.5 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GRIM-19 PF06212.7 CAM70788.1 - 0.038 13.6 0.0 0.084 12.5 0.0 1.5 1 0 0 1 1 1 0 GRIM-19 protein TPR_11 PF13414.1 CAM70789.1 - 1.8e-10 40.2 15.4 0.0021 17.6 0.5 5.8 5 0 0 5 5 5 4 TPR repeat TPR_16 PF13432.1 CAM70789.1 - 0.00088 19.8 40.4 0.24 12.1 0.1 7.4 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 CAM70789.1 - 0.0026 18.0 11.9 0.18 12.1 1.1 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 CAM70789.1 - 0.0051 16.7 18.8 8.7 6.3 0.0 6.6 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 CAM70789.1 - 3.4 7.8 30.5 2.1 8.4 0.1 8.5 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_1 PF00515.23 CAM70789.1 - 5.5 6.7 12.6 5.2 6.8 0.9 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Kinesin PF00225.18 CAM70790.1 - 2.3e-31 108.7 0.0 3e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain MORN PF02493.15 CAM70790.1 - 1.3e-16 59.2 36.9 0.0017 17.9 0.1 7.5 7 0 0 7 7 7 5 MORN repeat Ribosomal_L22 PF00237.14 CAM70791.1 - 2.7e-30 104.4 0.2 3.3e-30 104.1 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF1279 PF06916.8 CAM70792.1 - 1.3e-06 28.5 0.0 2.4e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) WW PF00397.21 CAM70792.1 - 0.0012 18.6 0.2 0.003 17.3 0.2 1.6 1 0 0 1 1 1 1 WW domain Fumarate_red_D PF02313.12 CAM70792.1 - 0.04 13.8 0.6 0.061 13.2 0.1 1.5 2 0 0 2 2 2 0 Fumarate reductase subunit D Ribosomal_S5_C PF03719.10 CAM70793.1 - 2e-24 84.6 0.0 3.3e-24 83.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 CAM70793.1 - 2.3e-21 75.3 0.3 3.6e-21 74.6 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Aldo_ket_red PF00248.16 CAM70794.1 - 3.1e-63 213.2 0.0 3.5e-63 213.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LRR_6 PF13516.1 CAM70795.1 - 1.6e-16 58.4 9.4 0.14 12.3 0.0 9.5 10 0 0 10 10 10 4 Leucine Rich repeat LRR_4 PF12799.2 CAM70795.1 - 4.1e-10 39.0 4.9 1.2 8.8 0.0 7.9 7 1 0 7 7 7 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CAM70795.1 - 3.4e-06 26.3 5.8 29 5.2 0.1 8.9 10 0 0 10 10 10 0 Leucine Rich Repeat Upf2 PF04050.9 CAM70795.1 - 0.17 11.6 16.1 0.42 10.3 11.2 1.7 1 0 0 1 1 1 0 Up-frameshift suppressor 2 RR_TM4-6 PF06459.7 CAM70795.1 - 1.5 8.6 11.8 3.1 7.6 8.2 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_polI_A34 PF08208.6 CAM70795.1 - 6 6.4 12.8 24 4.5 0.0 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Nop14 PF04147.7 CAM70795.1 - 8.9 4.0 27.2 15 3.3 18.9 1.3 1 0 0 1 1 1 0 Nop14-like family UQ_con PF00179.21 CAM70796.1 - 1e-34 118.9 0.0 1.6e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme S4 PF01479.20 CAM70797.1 - 0.00033 20.0 0.0 0.00061 19.1 0.0 1.5 1 0 0 1 1 1 1 S4 domain PHP PF02811.14 CAM70797.1 - 0.14 11.8 0.8 0.23 11.2 0.5 1.4 1 1 0 1 1 1 0 PHP domain Kinesin PF00225.18 CAM70798.1 - 3.4e-101 338.3 0.2 3.4e-101 338.3 0.2 3.1 3 0 0 3 3 3 1 Kinesin motor domain EF-hand_6 PF13405.1 CAM70800.1 - 1.6e-11 43.0 0.9 0.00038 20.1 0.0 3.8 3 1 1 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 CAM70800.1 - 1.4e-10 41.1 1.3 1.3e-05 25.2 0.3 2.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 CAM70800.1 - 6.5e-10 37.5 1.6 0.003 16.7 0.1 4.0 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.1 CAM70800.1 - 1.3e-07 31.1 7.7 0.0014 18.1 0.7 4.5 2 1 3 5 5 5 3 EF-hand domain pair EFhand_Ca_insen PF08726.5 CAM70800.1 - 1.3e-05 25.0 0.4 0.045 13.7 0.1 2.4 2 1 0 2 2 2 2 Ca2+ insensitive EF hand EF-hand_5 PF13202.1 CAM70800.1 - 0.00054 19.1 2.7 0.13 11.7 0.1 3.4 3 0 0 3 3 3 2 EF hand DUF2465 PF10239.4 CAM70800.1 - 0.014 14.5 0.1 0.02 14.1 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2465) YqeY PF09424.5 CAM70800.1 - 0.088 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Yqey-like protein Utp8 PF10395.4 CAM70800.1 - 0.12 10.6 0.1 0.14 10.4 0.1 1.0 1 0 0 1 1 1 0 Utp8 family AKAP7_NLS PF10469.4 CAM70801.1 - 5.6e-44 150.3 0.0 7e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.1 CAM70801.1 - 6.1e-08 32.5 0.0 9e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily DSPc PF00782.15 CAM70802.1 - 5.4e-14 51.9 0.0 1.2e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CAM70802.1 - 3.4e-11 42.9 0.0 8.3e-11 41.6 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CAM70802.1 - 3.4e-05 23.9 0.0 8.8e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.7 CAM70802.1 - 3.6e-05 23.2 0.0 6.8e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.1 CAM70802.1 - 0.0016 18.6 0.0 0.0042 17.3 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family AMMECR1 PF01871.12 CAM70803.1 - 2.4e-47 160.2 0.0 2.9e-47 159.9 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 WD40 PF00400.27 CAM70805.1 - 2.1e-16 59.0 5.0 6.9e-05 22.5 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat MMS1_N PF10433.4 CAM70805.1 - 0.12 10.4 0.0 0.24 9.4 0.0 1.6 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Vac_Fusion PF02346.11 CAM70806.1 - 0.34 10.3 2.3 0.56 9.6 0.1 2.4 2 0 0 2 2 2 0 Chordopoxvirus fusion protein DnaJ PF00226.26 CAM70807.1 - 1.8e-11 43.5 0.0 6.1e-11 41.8 0.0 2.0 1 0 0 1 1 1 1 DnaJ domain Synaptobrevin PF00957.16 CAM70807.1 - 3.8 7.1 6.0 15 5.3 0.7 3.4 3 1 0 3 3 3 0 Synaptobrevin Mnd1 PF03962.10 CAM70807.1 - 9.7 5.8 10.4 3.4 7.2 3.0 2.3 2 0 0 2 2 2 0 Mnd1 family Nucleoplasmin PF03066.10 CAM70808.1 - 0.19 11.2 3.8 0.32 10.5 2.7 1.3 1 0 0 1 1 1 0 Nucleoplasmin YL1 PF05764.8 CAM70808.1 - 0.42 10.1 14.4 0.04 13.5 6.6 1.7 2 0 0 2 2 2 0 YL1 nuclear protein Lin-8 PF03353.10 CAM70808.1 - 0.67 9.1 4.2 1.2 8.3 2.9 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Nop14 PF04147.7 CAM70808.1 - 6.1 4.6 10.6 9.6 3.9 7.3 1.2 1 0 0 1 1 1 0 Nop14-like family DEAD PF00270.24 CAM70809.1 - 3.4e-32 111.2 0.3 1.7e-31 108.9 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM70809.1 - 1.9e-25 88.5 0.2 7e-25 86.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAM70809.1 - 6e-08 32.7 0.3 1.5e-07 31.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CAM70809.1 - 0.0048 15.7 0.0 0.013 14.2 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.1 CAM70810.1 - 1.2e-05 24.8 17.4 2.1e-05 24.1 12.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF1691 PF07950.6 CAM70810.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1691) CHCH PF06747.8 CAM70811.1 - 0.00013 21.7 6.0 0.036 13.9 0.1 2.6 2 1 0 2 2 2 2 CHCH domain DUF1903 PF08991.5 CAM70811.1 - 0.00052 20.1 4.0 0.00052 20.1 2.8 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1903) Cmc1 PF08583.5 CAM70811.1 - 0.0066 16.1 10.0 0.059 13.1 0.3 2.9 2 1 1 3 3 3 2 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 CAM70811.1 - 0.72 9.9 6.6 0.29 11.2 0.4 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Colipase-like PF15083.1 CAM70811.1 - 4.3 7.3 7.2 3 7.8 0.8 2.1 1 1 1 2 2 2 0 Colipase-like DUF3716 PF12511.3 CAM70811.1 - 8.6 6.0 11.5 1.2 8.8 1.4 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3716) TauE PF01925.14 CAM70812.1 - 8.6e-21 74.4 23.4 8.1e-14 51.6 0.0 3.0 3 0 0 3 3 3 2 Sulfite exporter TauE/SafE Profilin PF00235.14 CAM70814.1 - 4.7e-39 133.2 0.1 5.7e-39 132.9 0.1 1.1 1 0 0 1 1 1 1 Profilin CDC50 PF03381.10 CAM70815.2 - 6.5e-59 199.3 0.0 8.9e-59 198.9 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Ras PF00071.17 CAM70817.1 - 3.3e-56 189.1 0.1 3.9e-56 188.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAM70817.1 - 2.6e-23 82.7 0.0 4.1e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAM70817.1 - 2.4e-15 56.2 0.0 2.8e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CAM70817.1 - 1.3e-07 31.2 0.1 5.4e-07 29.2 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CAM70817.1 - 4.7e-06 25.9 0.0 5.6e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CAM70817.1 - 9.7e-06 25.5 0.0 1.4e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.13 CAM70817.1 - 0.00072 18.6 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Septin PduV-EutP PF10662.4 CAM70817.1 - 0.00098 18.6 0.1 0.0042 16.5 0.1 1.9 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 CAM70817.1 - 0.0042 17.2 0.0 0.008 16.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 CAM70817.1 - 0.0095 15.1 0.0 0.019 14.1 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 CAM70817.1 - 0.01 15.8 0.1 0.013 15.4 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 CAM70817.1 - 0.018 14.7 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain cobW PF02492.14 CAM70817.1 - 0.027 13.9 0.1 5.8 6.3 0.0 2.2 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 CAM70817.1 - 0.038 13.5 0.0 0.052 13.1 0.0 1.3 1 1 0 1 1 1 0 AAA domain YwhD PF08741.5 CAM70817.1 - 0.057 12.8 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 YwhD family TGFb_propeptide PF00688.13 CAM70817.1 - 0.12 11.6 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 TGF-beta propeptide Rtf2 PF04641.7 CAM70820.1 - 3.6e-24 85.3 0.3 8.5e-24 84.1 0.2 1.5 1 1 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 CAM70820.1 - 0.00018 20.9 0.0 0.28 10.7 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 CAM70820.1 - 0.096 12.4 0.1 0.61 9.8 0.0 2.4 1 1 1 2 2 2 0 RING-type zinc-finger Mut7-C PF01927.11 CAM70821.1 - 7.7e-48 162.2 0.3 1.3e-47 161.4 0.2 1.3 1 0 0 1 1 1 1 Mut7-C RNAse domain zf-TFIIIC PF12660.2 CAM70821.1 - 0.04 13.8 0.7 1.4 8.9 0.1 2.5 2 0 0 2 2 2 0 Putative zinc-finger of transcription factor IIIC complex LSM PF01423.17 CAM70822.1 - 8.1e-10 38.1 0.1 1.1e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 LSM domain LRR_4 PF12799.2 CAM70824.1 - 1.5e-13 49.9 6.3 3e-07 29.9 0.0 3.9 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM70824.1 - 3.8e-11 42.5 7.9 7.8e-08 31.9 1.8 4.2 4 0 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 CAM70824.1 - 9.5e-05 21.9 8.4 1.8 8.8 0.0 6.0 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_6 PF13516.1 CAM70824.1 - 0.00021 21.0 4.4 0.72 10.1 0.1 4.3 4 0 0 4 4 4 2 Leucine Rich repeat LRR_7 PF13504.1 CAM70824.1 - 0.0031 17.4 9.3 0.83 10.1 0.2 5.2 5 0 0 5 5 5 2 Leucine rich repeat AAA_33 PF13671.1 CAM70824.1 - 0.065 13.1 0.2 0.065 13.1 0.1 2.6 2 1 0 2 2 2 0 AAA domain RRM_6 PF14259.1 CAM70826.1 - 1.2e-14 54.0 0.1 9.2e-08 31.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAM70826.1 - 1e-10 41.0 0.6 4.4e-05 23.0 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM70826.1 - 2.4e-09 36.8 0.5 0.00021 21.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MSP1_C PF07462.6 CAM70826.1 - 3 6.1 4.8 3.7 5.8 3.3 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Cyclin_N PF00134.18 CAM70827.1 - 5.9e-08 32.3 0.7 1e-07 31.5 0.5 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain RIC1 PF07064.8 CAM70828.2 - 1.9e-67 227.4 0.0 3.1e-67 226.7 0.0 1.3 1 0 0 1 1 1 1 RIC1 DUF1561 PF07598.6 CAM70828.2 - 0.093 10.6 0.0 0.14 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1561) IKI3 PF04762.7 CAM70828.2 - 0.33 8.7 0.0 1.6 6.4 0.0 2.0 3 0 0 3 3 3 0 IKI3 family Pkinase PF00069.20 CAM70829.1 - 1.5e-48 165.2 0.0 2.6e-48 164.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM70829.1 - 4.7e-30 104.5 0.0 8.6e-30 103.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CAM70829.1 - 0.00014 21.6 0.0 0.00038 20.2 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CAM70829.1 - 0.048 12.4 0.1 0.079 11.7 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.20 CAM70833.1 - 3.3e-48 164.0 0.0 5.3e-48 163.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM70833.1 - 1.9e-35 122.1 0.0 3.4e-35 121.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM70833.1 - 0.032 13.1 0.0 0.062 12.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like HAMP PF00672.20 CAM70833.1 - 0.04 14.0 0.8 0.13 12.4 0.4 2.0 2 0 0 2 2 2 0 HAMP domain Filaggrin PF03516.8 CAM70833.1 - 0.21 12.0 3.1 0.52 10.7 2.2 1.7 1 0 0 1 1 1 0 Filaggrin Cyclin PF08613.6 CAM70834.1 - 3.3e-25 89.2 0.6 4.4e-25 88.8 0.4 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CAM70834.1 - 2.5e-10 40.0 0.4 3.1e-10 39.7 0.3 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain RRM_5 PF13893.1 CAM70836.1 - 1.4e-05 24.8 0.1 0.17 11.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAM70836.1 - 0.004 16.7 0.0 0.057 13.0 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM70836.1 - 0.056 13.4 0.1 2.9 7.9 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.8 CAM70836.1 - 1 9.2 22.2 1.6 8.5 15.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RRM_5 PF13893.1 CAM70837.1 - 3.5e-15 55.5 0.1 0.00029 20.6 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM70837.1 - 7.3e-15 54.7 0.1 0.0013 18.6 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAM70837.1 - 7e-12 44.8 0.0 4.8e-05 22.9 0.0 3.8 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CAM70837.1 - 0.11 12.2 0.1 13 5.7 0.0 3.0 3 0 0 3 3 3 0 RNA binding motif TilS_C PF11734.3 CAM70838.1 - 0.034 13.3 0.0 0.12 11.5 0.0 1.9 2 0 0 2 2 2 0 TilS substrate C-terminal domain tRNA-synt_2d PF01409.15 CAM70839.1 - 2.8e-79 265.8 0.1 4e-79 265.2 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 CAM70839.1 - 3.3e-05 22.8 2.8 3.9e-05 22.5 0.2 2.2 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 CAM70839.1 - 6.4e-05 22.6 0.2 0.00019 21.0 0.1 1.8 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HTH_24 PF13412.1 CAM70839.1 - 0.072 12.4 0.0 0.38 10.1 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Ribosomal_L18ae PF01775.12 CAM70840.1 - 9.5e-41 138.5 1.7 1.3e-40 138.1 1.2 1.2 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain CTP_transf_2 PF01467.21 CAM70841.1 - 8.9e-33 113.5 0.1 4.2e-18 65.8 0.0 2.6 2 1 0 2 2 2 2 Cytidylyltransferase FAD_syn PF06574.7 CAM70841.1 - 2.4e-05 24.0 0.7 0.23 11.1 0.0 3.4 2 1 0 2 2 2 2 FAD synthetase CoA_binding_3 PF13727.1 CAM70841.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 CoA-binding domain AnfO_nitrog PF09582.5 CAM70842.1 - 0.082 12.0 0.1 0.098 11.7 0.0 1.2 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) Abhydrolase_6 PF12697.2 CAM70843.1 - 5.4e-20 72.2 0.0 7.2e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CAM70843.1 - 5.3e-07 29.4 0.0 6.1e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAM70843.1 - 4.1e-06 26.5 0.0 5.4e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.8 CAM70843.1 - 0.00077 19.1 0.1 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Ser_hydrolase PF06821.8 CAM70843.1 - 0.00097 18.7 0.0 0.0021 17.6 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase Lipase_3 PF01764.20 CAM70843.1 - 0.0018 17.8 0.0 0.0039 16.8 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Chlorophyllase2 PF12740.2 CAM70843.1 - 0.0047 15.8 0.0 0.01 14.7 0.0 1.5 2 0 0 2 2 2 1 Chlorophyllase enzyme Peptidase_S9 PF00326.16 CAM70843.1 - 0.016 14.4 0.0 0.036 13.2 0.0 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family PAF-AH_p_II PF03403.8 CAM70843.1 - 0.02 13.1 0.1 0.055 11.7 0.0 1.7 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_9 PF10081.4 CAM70843.1 - 0.038 12.6 0.0 0.05 12.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family Cutinase PF01083.17 CAM70843.1 - 0.043 13.5 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 Cutinase DUF900 PF05990.7 CAM70843.1 - 0.051 12.8 0.0 0.091 12.0 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) V_ATPase_I PF01496.14 CAM70844.1 - 5.3e-192 639.6 2.7 6.7e-192 639.2 1.8 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DAO PF01266.19 CAM70845.1 - 1.7e-07 30.4 0.2 6.5e-06 25.2 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase GMC_oxred_N PF00732.14 CAM70845.1 - 8.4e-07 28.4 0.2 0.00052 19.2 0.0 3.2 3 1 0 3 3 3 2 GMC oxidoreductase FAD_binding_2 PF00890.19 CAM70845.1 - 3.9e-05 22.7 1.1 0.0019 17.1 0.2 2.4 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 CAM70845.1 - 0.00085 19.2 0.1 0.0022 17.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CAM70845.1 - 0.0016 18.3 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CAM70845.1 - 0.0044 17.0 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CAM70845.1 - 0.0066 15.4 0.1 0.01 14.7 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 CAM70845.1 - 0.012 14.1 0.3 0.017 13.5 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.9 CAM70845.1 - 0.013 14.1 0.0 0.021 13.4 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.1 CAM70845.1 - 0.027 14.2 0.1 0.057 13.1 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.17 CAM70845.1 - 0.22 10.3 0.7 0.31 9.8 0.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A CLASP_N PF12348.3 CAM70846.1 - 3.4e-12 46.2 0.8 4e-10 39.4 0.2 2.5 2 0 0 2 2 2 2 CLASP N terminal Ipi1_N PF12333.3 CAM70846.1 - 0.13 12.2 8.6 8.3 6.4 0.0 4.7 4 1 0 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation HEAT PF02985.17 CAM70846.1 - 0.16 12.1 21.6 6.1 7.2 0.0 8.2 8 0 0 8 8 8 0 HEAT repeat Cnd1 PF12717.2 CAM70846.1 - 0.19 11.5 0.5 1.6 8.5 0.0 2.5 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 SNase PF00565.12 CAM70847.1 - 1.2e-53 179.9 3.1 1.3e-15 57.5 0.0 5.3 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 CAM70847.1 - 8.6e-17 61.1 0.0 1.7e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Tudor domain DUF4537 PF15057.1 CAM70847.1 - 0.026 14.3 0.0 0.088 12.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) Agenet PF05641.7 CAM70847.1 - 0.026 14.6 0.0 0.098 12.8 0.0 2.0 1 0 0 1 1 1 0 Agenet domain UQ_con PF00179.21 CAM70848.1 - 1.5e-40 137.8 0.0 2.1e-40 137.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Peptidase_C2 PF00648.16 CAM70849.1 - 2.9e-05 23.2 0.0 8.1e-05 21.7 0.0 1.7 1 0 0 1 1 1 1 Calpain family cysteine protease RRM_1 PF00076.17 CAM70850.1 - 0.0059 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Vps23_core PF09454.5 CAM70851.1 - 5.9e-19 67.4 0.0 1.3e-18 66.3 0.0 1.7 1 0 0 1 1 1 1 Vps23 core domain WD40 PF00400.27 CAM70852.1 - 2.7e-11 42.8 5.1 4.1e-07 29.6 0.1 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat Cpn60_TCP1 PF00118.19 CAM70853.1 - 1.9e-146 488.5 0.3 2.1e-146 488.3 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family BESS PF02944.15 CAM70853.1 - 0.11 12.0 0.0 0.52 9.9 0.0 2.0 2 0 0 2 2 2 0 BESS motif Y_phosphatase2 PF03162.8 CAM70854.1 - 2.4e-21 75.7 0.0 2.2e-20 72.7 0.0 2.1 1 1 0 1 1 1 1 Tyrosine phosphatase family Pkinase PF00069.20 CAM70855.1 - 1.5e-31 109.5 0.2 7.4e-27 94.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAM70855.1 - 4.6e-17 61.9 0.2 9.6e-17 60.9 0.2 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Maf PF02545.9 CAM70856.1 - 1.4e-16 60.1 0.0 1.6e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein Lge1 PF11488.3 CAM70857.1 - 0.0075 16.4 0.9 0.0075 16.4 0.6 4.4 4 1 0 4 4 4 1 Transcriptional regulatory protein LGE1 Thioredoxin_4 PF13462.1 CAM70857.1 - 0.079 12.9 3.4 0.15 12.0 0.1 2.4 2 0 0 2 2 2 0 Thioredoxin CALCOCO1 PF07888.6 CAM70857.1 - 0.089 11.0 26.2 0.0059 14.9 5.2 3.0 2 1 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Metallophos_2 PF12850.2 CAM70858.1 - 4.8e-14 52.4 0.0 5.6e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain WD40 PF00400.27 CAM70859.1 - 6.3e-15 54.3 6.8 0.00011 21.9 0.1 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat LSM PF01423.17 CAM70860.1 - 5.8e-14 51.3 0.1 6.8e-14 51.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain HECT PF00632.20 CAM70862.1 - 1.8e-73 247.4 0.0 2.6e-73 246.9 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ZZ PF00569.12 CAM70862.1 - 0.00053 19.4 8.8 0.00053 19.4 6.1 1.9 2 0 0 2 2 2 1 Zinc finger, ZZ type DUF2435 PF10363.4 CAM70862.1 - 0.018 14.9 0.0 0.55 10.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) CRM1_C PF08767.6 CAM70863.1 - 6.4e-62 209.3 0.6 6.4e-62 209.3 0.4 2.9 4 0 0 4 4 4 1 CRM1 C terminal Xpo1 PF08389.7 CAM70863.1 - 2.4e-26 92.4 1.0 2.4e-26 92.4 0.7 3.6 4 2 2 6 6 6 1 Exportin 1-like protein IBN_N PF03810.14 CAM70863.1 - 1.3e-08 34.6 0.1 1.2e-07 31.5 0.1 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain Mito_carr PF00153.22 CAM70864.1 - 2.5e-49 164.9 0.8 1.4e-17 63.1 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein PgaD PF13994.1 CAM70864.1 - 0.069 12.6 0.3 5.3 6.5 0.1 2.2 2 0 0 2 2 2 0 PgaD-like protein Mito_carr PF00153.22 CAM70865.1 - 7.7e-51 169.7 2.3 3.8e-19 68.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PPR_2 PF13041.1 CAM70867.1 - 0.0033 17.3 0.0 16 5.5 0.0 3.9 3 1 0 3 3 3 2 PPR repeat family PPR_3 PF13812.1 CAM70867.1 - 0.005 17.0 11.4 0.94 9.9 0.0 5.8 7 0 0 7 7 7 2 Pentatricopeptide repeat domain ELO PF01151.13 CAM70869.1 - 2.2e-52 177.8 18.6 2.9e-52 177.4 12.9 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Arabinose_Iso_C PF11762.3 CAM70870.1 - 0.02 14.4 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 L-arabinose isomerase C-terminal domain Ank_2 PF12796.2 CAM70871.1 - 4.9e-10 39.6 0.1 1.3e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CAM70871.1 - 1.8e-08 33.7 2.9 0.00061 19.4 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 CAM70871.1 - 4.9e-08 33.2 0.2 1.4e-07 31.8 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 CAM70871.1 - 1.4e-07 31.5 1.0 3.6e-07 30.1 0.7 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CAM70871.1 - 0.00021 21.2 0.6 0.057 13.6 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat PCI_Csn8 PF10075.4 CAM70873.1 - 2e-27 95.7 0.0 2.9e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 CAM70873.1 - 3.8e-21 75.5 0.4 5.7e-21 75.0 0.3 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family HhH-GPD PF00730.20 CAM70873.1 - 0.013 15.7 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein PD40 PF07676.7 CAM70873.1 - 0.053 13.2 0.0 0.099 12.3 0.0 1.4 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat PPR_2 PF13041.1 CAM70874.1 - 4.6e-41 138.5 20.2 7.1e-14 51.5 0.0 11.8 10 2 3 13 13 13 8 PPR repeat family PPR_3 PF13812.1 CAM70874.1 - 1.1e-22 78.3 31.3 3e-07 30.1 0.0 13.9 16 1 0 16 16 16 5 Pentatricopeptide repeat domain PPR PF01535.15 CAM70874.1 - 2e-14 52.4 17.2 3.3e-07 29.8 0.0 9.7 12 0 0 12 12 12 4 PPR repeat PPR_1 PF12854.2 CAM70874.1 - 9.5e-11 40.9 23.0 6.1e-09 35.2 0.0 8.2 9 0 0 9 9 9 2 PPR repeat COX5A PF02284.11 CAM70874.1 - 0.00062 19.6 0.1 1.4 8.8 0.0 2.7 1 1 1 2 2 2 2 Cytochrome c oxidase subunit Va ECSIT PF06239.6 CAM70874.1 - 0.0011 17.9 1.0 2.3 7.0 0.3 4.3 3 1 0 3 3 3 1 Evolutionarily conserved signalling intermediate in Toll pathway RPM2 PF08579.6 CAM70874.1 - 0.068 13.3 2.6 16 5.6 0.4 4.5 2 1 1 3 3 3 0 Mitochondrial ribonuclease P subunit (RPM2) TSC22 PF01166.13 CAM70875.1 - 3.1 7.8 9.4 0.11 12.5 0.6 2.9 3 0 0 3 3 3 0 TSC-22/dip/bun family GP38 PF05268.6 CAM70875.1 - 8.2 5.7 8.4 0.21 10.9 1.0 1.7 2 0 0 2 2 2 0 Phage tail fibre adhesin Gp38 ArfGap PF01412.13 CAM70876.1 - 1.3e-28 99.1 0.0 2.2e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TF_Zn_Ribbon PF08271.7 CAM70876.1 - 0.044 13.1 2.1 0.074 12.3 1.5 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding PHTB1_N PF14727.1 CAM70877.1 - 7.8e-93 311.6 0.0 1.4e-67 228.5 0.0 2.1 2 0 0 2 2 2 2 PTHB1 N-terminus PHTB1_C PF14728.1 CAM70877.1 - 3.7e-48 164.2 0.0 5.3e-48 163.7 0.0 1.1 1 0 0 1 1 1 1 PTHB1 C-terminus BBS2_Mid PF14783.1 CAM70877.1 - 0.11 12.3 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region UCH PF00443.24 CAM70878.1 - 8.5e-33 113.5 0.0 1.3e-32 112.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CAM70878.1 - 4.5e-20 72.2 0.0 2e-19 70.1 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CRAL_TRIO PF00650.15 CAM70879.1 - 5.7e-41 139.6 0.0 8e-41 139.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.1 CAM70879.1 - 0.00011 22.3 0.2 0.32 11.2 0.0 2.3 1 1 1 2 2 2 2 Golgi-dynamics membrane-trafficking CRAL_TRIO_N PF03765.10 CAM70879.1 - 0.0031 17.6 0.0 0.0083 16.2 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO PF00650.15 CAM70880.1 - 1e-29 103.0 0.0 2.1e-29 102.0 0.0 1.5 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 CAM70880.1 - 0.00025 20.9 0.0 0.00049 20.0 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain SHS2_Rpb7-N PF03876.12 CAM70881.1 - 5e-15 55.3 0.0 7.9e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Pkinase PF00069.20 CAM70882.1 - 7.9e-10 38.3 0.0 1.6e-09 37.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM70882.1 - 3.7e-06 26.1 0.0 5.6e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CAM70882.1 - 2.3e-05 24.2 0.1 8.2e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CAM70882.1 - 0.0028 17.2 0.0 0.0045 16.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pep_deformylase PF01327.16 CAM70883.1 - 3.4e-27 94.7 0.0 4.5e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase WLM PF08325.5 CAM70884.1 - 6.2e-32 110.9 0.0 3e-31 108.7 0.0 2.0 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.12 CAM70884.1 - 0.0023 17.7 2.1 0.005 16.6 1.5 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 Peptidase_C97 PF05903.9 CAM70886.1 - 3e-15 56.2 0.1 5.3e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain AAA_17 PF13207.1 CAM70888.1 - 2.8e-06 28.1 0.0 9.3e-06 26.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 CAM70888.1 - 0.0021 17.7 0.0 0.004 16.8 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 CAM70888.1 - 0.027 14.3 0.0 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CAM70888.1 - 0.039 13.9 0.4 0.12 12.3 0.3 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 CAM70888.1 - 0.066 13.1 0.0 0.37 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 CAM70888.1 - 0.072 13.2 0.1 0.19 11.8 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 CAM70888.1 - 0.095 13.0 0.0 0.19 12.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CAM70889.1 - 4.8e-08 33.8 0.0 1e-07 32.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain ADK PF00406.17 CAM70889.1 - 5.6e-07 29.5 0.0 1.4e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 Adenylate kinase mRNA_cap_enzyme PF01331.14 CAM70889.1 - 1.6e-06 27.9 0.0 2.5e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain AAA_18 PF13238.1 CAM70889.1 - 0.00023 21.4 0.0 0.00043 20.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CAM70889.1 - 0.0004 20.2 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain mRNA_cap_C PF03919.10 CAM70889.1 - 0.0011 19.3 0.0 0.0024 18.1 0.0 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain Thymidylate_kin PF02223.12 CAM70889.1 - 0.0032 16.8 0.0 1.1 8.6 0.0 2.3 2 0 0 2 2 2 2 Thymidylate kinase AAA_22 PF13401.1 CAM70889.1 - 0.015 15.4 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 CAM70889.1 - 0.039 13.8 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CAM70889.1 - 0.049 13.5 0.0 0.083 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 CAM70889.1 - 0.077 12.6 0.0 1.9 8.2 0.0 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 CAM70889.1 - 0.085 11.9 0.1 0.2 10.7 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin SRP54 PF00448.17 CAM70889.1 - 0.13 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DNA_ligase_A_M PF01068.16 CAM70889.1 - 0.15 11.4 0.0 6.5 6.0 0.0 2.2 2 0 0 2 2 2 0 ATP dependent DNA ligase domain LicD PF04991.8 CAM70890.1 - 1.8e-09 37.9 0.0 3.2e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 LicD family CPSF_A PF03178.10 CAM70891.1 - 1e-60 205.5 0.0 2.1e-60 204.4 0.0 1.6 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 CAM70891.1 - 2.4e-09 35.8 0.0 1.9e-07 29.6 0.0 2.7 2 1 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term Sec63 PF02889.11 CAM70893.1 - 5.5e-41 140.8 0.0 4.5e-38 131.2 0.0 2.5 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.24 CAM70893.1 - 1.3e-22 80.1 0.1 5.6e-22 78.0 0.1 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM70893.1 - 4.5e-07 29.6 0.0 1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAM70893.1 - 6.2e-06 26.1 0.0 1.9e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T2SE PF00437.15 CAM70893.1 - 0.016 14.1 0.0 0.035 13.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein UvrD-helicase PF00580.16 CAM70893.1 - 0.23 10.7 0.0 0.74 9.0 0.0 1.7 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 CAM70893.1 - 0.28 11.3 0.5 8.3 6.5 0.0 2.8 2 1 0 2 2 2 0 AAA domain EcoRI_methylase PF13651.1 CAM70893.1 - 0.42 9.6 0.0 0.67 8.9 0.0 1.2 1 0 0 1 1 1 0 Adenine-specific methyltransferase EcoRI Cyclase PF04199.8 CAM70894.1 - 6e-30 104.1 0.0 9e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase PPR_3 PF13812.1 CAM70895.1 - 0.34 11.3 7.8 1.3e+02 3.2 0.0 6.3 7 0 0 7 7 7 0 Pentatricopeptide repeat domain Extensin_2 PF04554.8 CAM70896.1 - 0.0087 15.8 8.4 0.0087 15.8 5.8 4.1 3 1 0 4 4 4 1 Extensin-like region Chloroa_b-bind PF00504.16 CAM70897.1 - 0.033 14.4 0.7 0.033 14.4 0.5 1.4 1 1 0 1 1 1 0 Chlorophyll A-B binding protein PI3_PI4_kinase PF00454.22 CAM70899.1 - 7e-38 130.4 0.3 1.4e-37 129.3 0.2 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 CAM70899.1 - 1.9e-12 46.8 0.8 1e-11 44.4 0.6 2.2 1 1 0 1 1 1 1 FAT domain FATC PF02260.15 CAM70899.1 - 3.4e-12 45.5 4.0 4.8e-12 45.0 1.0 2.7 2 0 0 2 2 2 1 FATC domain MIP-T3 PF10243.4 CAM70900.1 - 2.6e-15 55.9 1.1 2.6e-15 55.9 0.7 1.7 1 1 0 1 1 1 1 Microtubule-binding protein MIP-T3 YqaJ PF09588.5 CAM70903.1 - 8.4e-63 210.8 0.0 3.7e-62 208.8 0.0 2.0 1 1 0 1 1 1 1 YqaJ-like viral recombinase domain NUDIX PF00293.23 CAM70906.1 - 5.1e-06 26.1 0.0 1.9e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 NUDIX domain PSP1 PF04468.7 CAM70907.1 - 5.1e-25 87.2 1.4 8.9e-25 86.4 0.8 1.6 2 0 0 2 2 2 1 PSP1 C-terminal conserved region eIF3_p135 PF12807.2 CAM70908.1 - 5.6e-11 42.6 0.0 9e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 CLU PF13236.1 CAM70908.1 - 0.03 13.7 0.0 0.091 12.1 0.0 1.7 3 0 0 3 3 3 0 Clustered mitochondria Y_phosphatase PF00102.22 CAM70908.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase ArfGap PF01412.13 CAM70909.1 - 7.3e-41 138.6 0.1 1.2e-40 137.9 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PMI_typeI PF01238.16 CAM70910.1 - 1.9e-90 303.5 0.0 2.2e-90 303.3 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I PIF1 PF05970.9 CAM70911.1 - 7e-36 123.9 0.3 2.2e-15 56.5 0.0 4.2 4 0 0 4 4 4 3 PIF1-like helicase AAA_30 PF13604.1 CAM70911.1 - 4.5e-11 42.6 2.8 6.9e-10 38.8 0.8 3.1 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CAM70911.1 - 3.9e-06 26.5 0.4 1.7e-05 24.4 0.3 2.1 1 0 0 1 1 1 1 Part of AAA domain Herpes_Helicase PF02689.9 CAM70911.1 - 3.2e-05 21.9 0.8 0.078 10.7 0.0 2.3 2 0 0 2 2 2 2 Helicase Viral_helicase1 PF01443.13 CAM70911.1 - 0.00066 19.2 0.1 5 6.5 0.0 3.5 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 CAM70911.1 - 0.0011 19.1 0.0 0.0031 17.6 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain IstB_IS21 PF01695.12 CAM70911.1 - 0.0015 17.9 0.6 0.005 16.2 0.1 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein Helicase_RecD PF05127.9 CAM70911.1 - 0.0021 17.7 0.7 0.23 11.0 0.3 2.5 2 0 0 2 2 2 1 Helicase AAA_22 PF13401.1 CAM70911.1 - 0.0025 17.9 0.0 0.15 12.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CAM70911.1 - 0.0046 16.9 0.5 0.011 15.7 0.0 1.8 2 0 0 2 2 1 1 AAA ATPase domain MobB PF03205.9 CAM70911.1 - 0.0096 15.6 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 CAM70911.1 - 0.01 15.5 0.2 0.27 10.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PhoH PF02562.11 CAM70911.1 - 0.013 14.7 0.3 0.024 13.8 0.2 1.3 1 0 0 1 1 1 0 PhoH-like protein Bac_DnaA PF00308.13 CAM70911.1 - 0.014 15.0 0.0 0.082 12.5 0.0 1.9 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_25 PF13481.1 CAM70911.1 - 0.021 14.2 0.6 0.13 11.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 CAM70911.1 - 0.047 13.3 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.1 CAM70911.1 - 0.05 13.1 0.1 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 CAM70911.1 - 0.078 12.4 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain ArgK PF03308.11 CAM70911.1 - 0.08 11.7 0.2 0.18 10.5 0.1 1.5 1 0 0 1 1 1 0 ArgK protein ABC_tran PF00005.22 CAM70911.1 - 0.092 13.0 0.4 0.22 11.8 0.3 1.5 1 0 0 1 1 1 0 ABC transporter NTPase_1 PF03266.10 CAM70911.1 - 0.095 12.4 0.1 0.59 9.8 0.0 2.1 2 0 0 2 2 2 0 NTPase Zeta_toxin PF06414.7 CAM70911.1 - 0.13 11.3 0.1 0.25 10.4 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.4 CAM70911.1 - 0.52 9.2 0.3 1.3 7.8 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NAD_synthase PF02540.12 CAM70919.1 - 5.9e-33 113.7 0.0 7.3e-33 113.4 0.0 1.1 1 0 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 CAM70919.1 - 0.045 13.2 0.0 0.064 12.7 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase PAPS_reduct PF01507.14 CAM70919.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family PP2C PF00481.16 CAM70921.1 - 4.9e-68 229.2 0.0 8.1e-68 228.5 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoU_methylase PF00588.14 CAM70923.1 - 5.2e-10 39.3 0.0 0.01 15.7 0.0 3.7 4 0 0 4 4 4 3 SpoU rRNA Methylase family DNA_pol_E_B PF04042.11 CAM70924.1 - 8e-14 51.3 0.1 8.1e-12 44.8 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase alpha/epsilon subunit B Coatomer_E PF04733.9 CAM70925.1 - 6.8e-30 104.2 6.3 6.1e-29 101.1 4.3 1.9 1 1 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 CAM70925.1 - 4.4e-07 30.1 6.7 0.024 14.9 0.1 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 CAM70925.1 - 8.6e-07 28.5 4.9 1e-05 25.0 0.9 3.1 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 CAM70925.1 - 1.2e-05 24.8 5.1 0.31 11.0 0.0 5.1 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 CAM70925.1 - 1.6e-05 25.4 17.1 0.00094 19.7 2.3 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 CAM70925.1 - 1.6e-05 24.7 5.0 0.00028 20.7 1.0 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CAM70925.1 - 0.00012 22.3 11.9 0.18 12.5 0.9 5.0 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 CAM70925.1 - 0.0037 16.7 3.5 0.48 10.1 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 CAM70925.1 - 0.0044 17.1 2.4 0.7 10.0 0.7 3.3 2 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 CAM70925.1 - 0.0071 16.2 3.6 0.78 9.7 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 CAM70925.1 - 0.052 14.0 2.0 0.44 11.1 0.2 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CAM70925.1 - 0.1 12.4 0.3 4.3 7.3 0.0 2.6 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Dispanin PF04505.7 CAM70925.1 - 0.24 10.9 1.5 1.9 8.1 0.0 2.7 2 0 0 2 2 2 0 Interferon-induced transmembrane protein TPR_7 PF13176.1 CAM70925.1 - 0.73 9.7 3.7 9.6 6.2 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 CAM70925.1 - 2.8 7.9 6.5 4.5 7.2 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat WW PF00397.21 CAM70926.1 - 7.4e-12 44.9 1.2 1.1e-11 44.3 0.8 1.3 1 0 0 1 1 1 1 WW domain zf-CCCH PF00642.19 CAM70926.1 - 2.1e-06 27.2 1.5 3e-06 26.7 0.4 1.7 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CBM_2 PF00553.14 CAM70926.1 - 0.03 14.3 0.0 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 Cellulose binding domain zf-CCCH_2 PF14608.1 CAM70926.1 - 0.037 14.0 0.2 0.076 13.0 0.2 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type PUF PF00806.14 CAM70927.1 - 5.9e-23 79.0 0.0 0.017 14.5 0.0 9.1 10 0 0 10 10 10 7 Pumilio-family RNA binding repeat YajC PF02699.10 CAM70928.1 - 0.11 12.2 0.3 0.45 10.2 0.2 1.9 2 0 0 2 2 2 0 Preprotein translocase subunit PBP PF01161.15 CAM70929.1 - 3e-06 27.1 0.3 8.2e-06 25.7 0.2 1.7 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein SART-1 PF03343.8 CAM70932.1 - 0.033 12.5 6.2 0.054 11.8 4.3 1.2 1 0 0 1 1 1 0 SART-1 family Kisspeptin PF15152.1 CAM70933.1 - 0.027 15.1 0.1 0.06 14.0 0.1 1.6 1 0 0 1 1 1 0 Kisspeptin Herpes_capsid PF06112.6 CAM70933.1 - 0.26 11.3 4.9 0.39 10.7 3.4 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Pkinase PF00069.20 CAM70934.1 - 7.6e-44 149.7 0.0 2.5e-43 148.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM70934.1 - 2.9e-30 105.2 0.0 1.5e-29 102.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 CAM70934.1 - 2.1e-06 27.9 0.0 3.7e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 CAM70934.1 - 4e-05 22.7 0.0 6.4e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PH_9 PF15410.1 CAM70934.1 - 0.0042 17.2 0.0 0.0087 16.2 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain Sod_Fe_C PF02777.13 CAM70935.1 - 5.3e-43 145.1 0.0 8.6e-43 144.5 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 CAM70935.1 - 3.3e-18 65.7 0.3 7.2e-18 64.6 0.0 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.13 CAM70936.1 - 2.2e-42 143.1 0.1 3.8e-42 142.4 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 CAM70936.1 - 4.1e-18 65.4 0.6 8.4e-18 64.4 0.0 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Ras PF00071.17 CAM70937.1 - 6.7e-36 123.1 0.0 8.3e-36 122.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAM70937.1 - 1.8e-16 60.7 0.0 2.7e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAM70937.1 - 2.6e-10 39.8 0.0 3.1e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CAM70937.1 - 4.7e-07 29.1 0.0 5.5e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CAM70937.1 - 7.2e-07 28.5 0.0 1.2e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 CAM70937.1 - 3.4e-06 26.6 0.0 0.00017 21.0 0.0 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CAM70937.1 - 2.1e-05 24.4 0.0 3.3e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 CAM70937.1 - 0.0014 18.1 0.0 0.0025 17.3 0.0 1.4 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein Cpn60_TCP1 PF00118.19 CAM70938.1 - 5.1e-120 401.3 3.3 6.1e-120 401.0 2.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AKAP95 PF04988.7 CAM70938.1 - 0.11 12.2 0.0 28 4.4 0.0 3.1 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) Cation_efflux PF01545.16 CAM70940.1 - 7.8e-63 212.1 0.8 1e-62 211.8 0.6 1.1 1 0 0 1 1 1 1 Cation efflux family CBFD_NFYB_HMF PF00808.18 CAM70941.1 - 0.00088 19.2 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DNA_pol_A_exo1 PF01612.15 CAM70942.1 - 4.2e-10 39.3 0.0 1.6e-09 37.5 0.0 1.8 1 1 0 1 1 1 1 3'-5' exonuclease rRNA_processing PF08524.6 CAM70946.1 - 1.3e-08 34.7 18.6 1.3e-08 34.7 12.9 2.3 1 1 1 2 2 2 1 rRNA processing Peripla_BP_3 PF13377.1 CAM70946.1 - 0.18 11.8 1.0 0.29 11.1 0.1 1.7 1 1 1 2 2 2 0 Periplasmic binding protein-like domain DCX PF03607.12 CAM70947.1 - 0.069 12.7 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Doublecortin Peptidase_M41 PF01434.13 CAM70948.2 - 5.7e-50 169.7 0.4 8.5e-50 169.1 0.3 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CAM70948.2 - 3.6e-41 140.4 0.0 7e-41 139.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CAM70948.2 - 0.00025 21.0 0.1 0.0023 17.9 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 CAM70948.2 - 0.00096 18.8 0.2 0.0038 16.9 0.2 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 CAM70948.2 - 0.0015 18.6 0.1 0.011 15.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CAM70948.2 - 0.0024 16.9 0.0 0.0052 15.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 CAM70948.2 - 0.0031 18.3 0.0 0.0077 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CAM70948.2 - 0.0033 17.1 0.0 0.016 14.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 CAM70948.2 - 0.0082 14.8 0.0 0.017 13.8 0.0 1.4 1 1 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 CAM70948.2 - 0.012 15.0 0.8 0.083 12.2 0.2 2.2 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.7 CAM70948.2 - 0.014 14.5 0.0 0.029 13.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.1 CAM70948.2 - 0.024 14.5 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 CAM70948.2 - 0.027 13.9 0.1 0.057 12.8 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.21 CAM70948.2 - 0.028 13.9 0.0 0.15 11.5 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain DUF2075 PF09848.4 CAM70948.2 - 0.053 12.4 0.0 0.09 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 CAM70948.2 - 0.1 12.2 0.0 0.81 9.3 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_2 PF07724.9 CAM70948.2 - 0.13 12.1 0.5 1.4 8.8 0.2 2.5 1 1 1 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 CAM70948.2 - 0.13 12.5 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 CAM70948.2 - 0.17 11.7 0.5 0.4 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF1663 PF07909.6 CAM70951.1 - 0.11 11.0 9.3 0.01 14.4 2.9 1.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1663) DUF647 PF04884.9 CAM70952.1 - 3.5e-22 78.7 5.7 5.6e-22 78.1 4.0 1.3 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Phlebovirus_NSM PF07246.6 CAM70953.1 - 2.6 7.1 6.0 1.5 7.9 2.8 1.5 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M CTDII PF01556.13 CAM70954.1 - 6.6e-26 90.0 0.0 2.5e-19 68.9 0.0 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 CAM70954.1 - 3.2e-16 58.8 0.7 6.2e-16 57.8 0.5 1.5 1 1 0 1 1 1 1 DnaJ domain Qn_am_d_aII PF14930.1 CAM70954.1 - 0.049 13.5 0.1 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II Acyltransferase PF01553.16 CAM70956.1 - 4.2e-16 58.5 0.1 1e-15 57.3 0.0 1.6 2 0 0 2 2 2 1 Acyltransferase Lipase_GDSL_3 PF14606.1 CAM70956.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family DUF367 PF04034.8 CAM70958.1 - 4.6e-46 155.5 0.0 6e-46 155.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 CAM70958.1 - 1.8e-11 43.4 0.0 3.7e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI DUF2839 PF10999.3 CAM70959.1 - 4.6 7.3 7.1 1 9.4 1.9 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2839) DUF4200 PF13863.1 CAM70960.1 - 8.4e-25 87.1 14.3 8.4e-25 87.1 9.9 4.2 4 0 0 4 4 4 2 Domain of unknown function (DUF4200) IncA PF04156.9 CAM70960.1 - 0.012 15.1 3.3 0.012 15.1 2.3 3.5 3 1 0 3 3 3 0 IncA protein GP41 PF00517.12 CAM70960.1 - 0.22 11.0 1.6 3.2 7.2 0.4 2.5 2 0 0 2 2 2 0 Retroviral envelope protein DUF1664 PF07889.7 CAM70960.1 - 0.31 10.8 3.7 4.3 7.1 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Tnp_P_element PF12017.3 CAM70960.1 - 0.58 9.3 4.7 4.7 6.3 0.1 2.7 2 0 0 2 2 2 0 Transposase protein Mst1_SARAH PF11629.3 CAM70960.1 - 0.64 9.8 10.2 8.1 6.3 0.0 5.0 5 0 0 5 5 5 0 C terminal SARAH domain of Mst1 Endosulfine PF04667.12 CAM70961.1 - 5.6e-07 29.4 6.7 5.6e-07 29.4 4.6 1.5 2 0 0 2 2 2 1 cAMP-regulated phosphoprotein/endosulfine conserved region Neur_chan_memb PF02932.11 CAM70961.1 - 0.29 10.9 1.5 0.3 10.9 1.1 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Med15 PF09606.5 CAM70961.1 - 1.1 7.3 25.6 1.1 7.3 17.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Activator_LAG-3 PF11498.3 CAM70961.1 - 1.9 7.1 23.5 2.3 6.8 16.3 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Suf PF05843.9 CAM70961.1 - 1.9 8.1 12.4 2.2 7.9 8.6 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Shisa PF13908.1 CAM70961.1 - 2.9 8.0 10.7 3.7 7.6 7.4 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4175 PF13779.1 CAM70961.1 - 5.3 4.6 20.4 5.8 4.4 14.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF605 PF04652.11 CAM70961.1 - 6.8 5.9 15.1 7.7 5.8 10.5 1.2 1 0 0 1 1 1 0 Vta1 like Lin-8 PF03353.10 CAM70961.1 - 7.3 5.7 9.7 8.4 5.5 6.7 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PAT1 PF09770.4 CAM70961.1 - 7.8 4.5 27.1 7.7 4.6 18.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4557 PF15101.1 CAM70961.1 - 8.1 6.2 11.2 9.6 5.9 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DDRGK PF09756.4 CAM70961.1 - 8.9 5.6 7.6 10 5.4 5.3 1.0 1 0 0 1 1 1 0 DDRGK domain DUF3456 PF11938.3 CAM70962.1 - 3.4e-10 40.0 8.7 7.7e-10 38.9 2.8 2.8 2 1 0 2 2 2 1 TLR4 regulator and MIR-interacting MSAP DUF4633 PF15464.1 CAM70962.1 - 0.013 15.3 3.5 0.12 12.1 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4633) MIR PF02815.14 CAM70963.1 - 0.02 14.4 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 MIR domain EMP24_GP25L PF01105.19 CAM70964.1 - 4.6e-31 107.9 0.0 5.1e-31 107.8 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ras PF00071.17 CAM70965.1 - 9.4e-61 203.9 0.0 1.1e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAM70965.1 - 9.8e-19 68.0 0.0 1.5e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAM70965.1 - 1.5e-12 47.1 0.0 1.8e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CAM70965.1 - 4.9e-05 22.5 0.0 7e-05 22.0 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CAM70965.1 - 0.00028 20.3 0.0 0.0012 18.2 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CAM70965.1 - 0.00054 19.9 0.0 0.0011 18.8 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FA_synthesis PF02504.10 CAM70965.1 - 0.013 14.4 0.1 0.017 14.0 0.0 1.1 1 0 0 1 1 1 0 Fatty acid synthesis protein AAA_24 PF13479.1 CAM70965.1 - 0.014 14.9 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CAM70965.1 - 0.022 14.8 0.0 0.058 13.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 CAM70965.1 - 0.029 13.5 0.1 0.086 12.0 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function, DUF258 DUF3234 PF11572.3 CAM70965.1 - 0.041 13.9 0.0 0.069 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3234) AAA_16 PF13191.1 CAM70965.1 - 0.059 13.3 0.2 0.11 12.4 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 CAM70968.1 - 2.4e-17 63.4 0.0 4.5e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CAM70968.1 - 1.6e-12 48.0 0.1 1.2e-07 32.0 0.1 2.3 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 CAM70968.1 - 4.3e-07 29.4 0.0 3.3e-06 26.4 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 CAM70968.1 - 0.00017 20.8 0.0 0.0012 18.0 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain ABC_membrane PF00664.18 CAM70968.1 - 0.00058 19.3 8.3 0.00058 19.3 5.7 1.8 2 1 0 2 2 1 1 ABC transporter transmembrane region DUF258 PF03193.11 CAM70968.1 - 0.00086 18.5 0.0 0.0017 17.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CAM70968.1 - 0.0013 18.8 1.6 0.023 14.8 1.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CAM70968.1 - 0.0023 17.9 0.7 0.01 15.8 0.5 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.1 CAM70968.1 - 0.0066 16.7 0.0 0.011 16.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 CAM70968.1 - 0.0086 16.2 0.2 0.18 11.9 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 CAM70968.1 - 0.016 14.6 0.1 0.055 12.8 0.1 1.9 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 CAM70968.1 - 0.017 14.9 0.1 0.14 12.0 0.0 2.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 CAM70968.1 - 0.027 12.9 0.0 4.1 5.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.10 CAM70968.1 - 0.028 13.0 0.0 0.045 12.3 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein RNA_helicase PF00910.17 CAM70968.1 - 0.059 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.1 CAM70968.1 - 0.059 12.8 0.1 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 CAM70968.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Rad17 PF03215.10 CAM70968.1 - 0.15 10.7 0.3 0.23 10.1 0.2 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 CAM70968.1 - 0.43 11.4 1.6 0.7 10.7 0.2 2.0 2 0 0 2 2 2 0 AAA domain CTP_transf_2 PF01467.21 CAM70969.1 - 3.1e-07 30.5 0.0 8.1e-07 29.2 0.0 1.8 1 1 0 1 1 1 1 Cytidylyltransferase FAD_syn PF06574.7 CAM70969.1 - 0.02 14.5 0.1 0.15 11.6 0.1 2.1 2 0 0 2 2 2 0 FAD synthetase dCMP_cyt_deam_1 PF00383.17 CAM70970.1 - 4.1e-07 29.5 0.0 1.5e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 CAM70970.1 - 0.0015 18.3 0.0 0.0055 16.5 0.0 2.0 2 0 0 2 2 2 1 Bd3614-like deaminase Methyltransf_26 PF13659.1 CAM70971.1 - 6.4e-16 58.4 0.2 1.1e-15 57.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 CAM70971.1 - 0.037 13.4 0.0 0.075 12.4 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_25 PF13649.1 CAM70971.1 - 0.039 14.3 0.2 0.37 11.1 0.1 2.5 1 1 0 1 1 1 0 Methyltransferase domain TMPIT PF07851.8 CAM70972.1 - 0.25 10.3 2.1 0.51 9.3 1.4 1.4 1 0 0 1 1 1 0 TMPIT-like protein DUF677 PF05055.7 CAM70972.1 - 2.1 6.9 9.6 0.31 9.6 2.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF677) CDC37_N PF03234.9 CAM70972.1 - 9.7 6.4 12.8 2.4 8.4 6.0 2.0 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding DUF4234 PF14018.1 CAM70974.1 - 0.059 13.1 0.1 0.059 13.1 0.0 3.4 3 2 0 3 3 3 0 Domain of unknown function (DUF4234) RRM_1 PF00076.17 CAM70975.1 - 2.2e-07 30.3 0.0 4.1e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM70975.1 - 0.00011 22.0 0.1 0.00028 20.7 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.1 CAM70975.1 - 0.0003 20.8 0.1 0.0003 20.8 0.1 2.1 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_5 PF13893.1 CAM70975.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HEAT_EZ PF13513.1 CAM70977.1 - 4.2e-09 36.6 4.3 0.51 10.9 0.0 7.1 7 0 0 7 7 7 3 HEAT-like repeat HEAT PF02985.17 CAM70977.1 - 6.3e-09 35.1 8.5 0.052 13.6 0.3 6.5 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.1 CAM70977.1 - 4.6e-07 30.0 0.4 0.001 19.3 0.0 4.7 4 1 1 5 5 5 2 HEAT repeats Cnd1 PF12717.2 CAM70977.1 - 9.7e-05 22.2 0.3 0.00097 19.0 0.0 2.6 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Utp12 PF04003.7 CAM70977.1 - 0.018 14.9 0.2 0.55 10.1 0.0 3.3 4 0 0 4 4 4 0 Dip2/Utp12 Family Synaptobrevin PF00957.16 CAM70979.1 - 1e-08 34.6 4.0 2.2e-08 33.5 2.8 1.5 1 0 0 1 1 1 1 Synaptobrevin EcoR124_C PF12008.3 CAM70979.1 - 0.41 9.8 0.8 0.64 9.1 0.5 1.2 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal DUF605 PF04652.11 CAM70979.1 - 1.8 7.8 11.0 2.7 7.2 7.6 1.2 1 0 0 1 1 1 0 Vta1 like PCI_Csn8 PF10075.4 CAM70981.1 - 5.2e-14 52.2 0.0 9.2e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 CAM70981.1 - 2.3e-11 43.6 0.0 3e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI PF01399.22 CAM70981.1 - 0.0012 19.1 0.0 0.0017 18.6 0.0 1.3 1 0 0 1 1 1 1 PCI domain GTP_EFTU PF00009.22 CAM70983.1 - 6e-26 91.0 0.0 6.3e-25 87.7 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 CAM70983.1 - 3e-15 55.8 0.0 8.1e-15 54.4 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.1 CAM70983.1 - 1.1e-08 34.7 0.0 2.2e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Elongation Factor G, domain II Miro PF08477.8 CAM70983.1 - 6.8e-08 33.0 0.0 1.2e-07 32.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein EFG_IV PF03764.13 CAM70983.1 - 6.4e-07 28.9 0.0 1.4e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 CAM70983.1 - 2e-06 27.7 0.0 3.5e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CAM70983.1 - 1.2e-05 25.1 0.1 0.023 14.5 0.0 2.3 1 1 1 2 2 2 2 Dynamin family SRPRB PF09439.5 CAM70983.1 - 0.002 17.3 0.0 0.0032 16.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Septin PF00735.13 CAM70983.1 - 0.005 15.9 0.0 0.0076 15.3 0.0 1.2 1 0 0 1 1 1 1 Septin PduV-EutP PF10662.4 CAM70983.1 - 0.26 10.7 0.0 7.8 5.9 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Complex1_LYR PF05347.10 CAM70984.1 - 3.7e-10 39.4 1.4 3.7e-10 39.4 1.0 1.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CAM70984.1 - 1.9e-08 34.3 1.1 1.9e-08 34.3 0.7 2.1 2 0 0 2 2 2 1 Complex1_LYR-like DnaB_bind PF10410.4 CAM70984.1 - 2.8 7.9 6.6 2.2 8.3 0.2 3.2 4 0 0 4 4 4 0 DnaB-helicase binding domain of primase BBP1_C PF15272.1 CAM70985.1 - 8.5e-05 22.1 163.1 0.011 15.2 9.2 10.6 2 2 12 14 14 14 10 Spindle pole body component BBP1, C-terminal DUF3135 PF11333.3 CAM70985.1 - 0.00014 21.9 94.9 0.32 11.1 2.5 13.3 3 1 10 13 13 13 10 Protein of unknown function (DUF3135) Spc7 PF08317.6 CAM70985.1 - 0.00018 20.3 13.7 0.00018 20.3 9.5 8.6 4 1 7 11 11 11 1 Spc7 kinetochore protein ADIP PF11559.3 CAM70985.1 - 0.0023 17.8 5.3 0.0023 17.8 3.7 14.5 7 2 13 20 20 20 1 Afadin- and alpha -actinin-Binding DEAD PF00270.24 CAM70986.1 - 1.5e-40 138.4 0.0 2.9e-40 137.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM70986.1 - 4.6e-21 74.4 0.0 1.1e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CAM70986.1 - 7.7e-14 50.9 0.1 1.7e-13 49.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 CAM70986.1 - 0.01 15.6 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Formyl_trans_N PF00551.14 CAM70987.1 - 8.2e-16 58.0 0.0 1.7e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase Cas_Cas02710 PF09670.5 CAM70988.1 - 0.074 11.6 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) CS PF04969.11 CAM70989.1 - 2.3e-05 24.8 0.0 2.3e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 CS domain PAP2 PF01569.16 CAM70992.1 - 1.5e-16 60.2 2.8 1.5e-16 60.2 1.9 2.2 2 1 0 2 2 2 1 PAP2 superfamily ERG4_ERG24 PF01222.12 CAM70995.1 - 2.8e-124 414.9 4.1 3.2e-124 414.7 2.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 CAM70995.1 - 2.3e-08 33.6 0.6 1.1e-07 31.3 0.2 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.8 CAM70995.1 - 8.1e-06 25.9 0.1 3.6e-05 23.8 0.0 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 CAM70995.1 - 0.0067 16.6 0.0 0.0067 16.6 0.0 3.2 4 0 0 4 4 4 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family EamA PF00892.15 CAM70996.1 - 8e-05 22.6 7.0 0.0001 22.3 4.9 1.3 1 1 0 1 1 1 1 EamA-like transporter family TPT PF03151.11 CAM70996.1 - 0.007 16.0 2.9 0.0093 15.6 1.9 1.3 1 1 0 1 1 1 1 Triose-phosphate Transporter family UPF0546 PF10639.4 CAM70996.1 - 0.02 14.7 1.0 0.024 14.4 0.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0546 EmrE PF13536.1 CAM70996.1 - 0.084 13.0 5.0 0.13 12.4 3.5 1.3 1 0 0 1 1 1 0 Multidrug resistance efflux transporter DUF21 PF01595.15 CAM70996.1 - 4.3 6.5 7.1 1.2 8.4 1.8 1.9 1 1 0 2 2 2 0 Domain of unknown function DUF21 Miff PF05644.6 CAM70997.1 - 0.033 13.8 0.6 0.084 12.4 0.1 1.9 2 0 0 2 2 2 0 Mitochondrial and peroxisomal fission factor Mff MIP PF00230.15 CAM70998.1 - 2.9e-29 102.1 15.9 4.2e-29 101.6 11.0 1.2 1 0 0 1 1 1 1 Major intrinsic protein Podoplanin PF05808.6 CAM70998.1 - 0.19 11.2 2.0 0.59 9.6 1.4 1.8 1 0 0 1 1 1 0 Podoplanin MIP PF00230.15 CAM70999.1 - 1e-34 120.0 17.6 1.2e-34 119.7 12.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein PPR_3 PF13812.1 CAM71000.1 - 0.022 15.0 0.0 7 7.2 0.0 4.4 4 0 0 4 4 4 0 Pentatricopeptide repeat domain Nsp1_C PF05064.8 CAM71001.1 - 8.3e-10 38.3 0.4 1.4e-09 37.6 0.3 1.3 1 0 0 1 1 1 1 Nsp1-like C-terminal region Cep57_MT_bd PF06657.8 CAM71001.1 - 0.0031 17.4 1.3 0.0055 16.6 0.4 1.8 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 Myosin_tail_1 PF01576.14 CAM71001.1 - 0.0076 14.0 3.8 0.01 13.6 2.7 1.1 1 0 0 1 1 1 1 Myosin tail Cluap1 PF10234.4 CAM71001.1 - 0.058 12.5 0.5 0.093 11.9 0.4 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Tropomyosin_1 PF12718.2 CAM71001.1 - 0.077 12.8 1.5 0.12 12.2 1.1 1.2 1 0 0 1 1 1 0 Tropomyosin like Spc7 PF08317.6 CAM71001.1 - 0.12 11.0 0.9 0.6 8.7 0.5 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein ATG16 PF08614.6 CAM71001.1 - 0.14 11.9 2.5 0.11 12.3 0.6 1.6 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Phage_GPO PF05929.6 CAM71001.1 - 0.25 10.5 3.3 0.5 9.5 2.3 1.5 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase RTBV_P46 PF06216.6 CAM71001.1 - 0.42 9.3 0.2 0.56 8.9 0.1 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein IncA PF04156.9 CAM71001.1 - 0.88 9.1 7.0 2.7 7.5 4.8 1.8 1 1 0 1 1 1 0 IncA protein CENP-F_leu_zip PF10473.4 CAM71001.1 - 0.95 9.3 4.1 2.1 8.2 0.5 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NAD_binding_1 PF00175.16 CAM71002.1 - 1e-16 61.4 0.0 4.4e-11 43.3 0.0 2.4 1 1 1 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CAM71002.1 - 4.1e-11 42.8 0.0 6.8e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 CAM71002.1 - 0.0007 19.5 0.0 0.0016 18.3 0.0 1.6 1 1 0 1 1 1 1 Ferric reductase NAD binding domain TPR_12 PF13424.1 CAM71004.1 - 1.1e-06 28.5 13.4 1.3e-06 28.2 1.9 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 CAM71004.1 - 7.5e-06 25.5 10.7 3.5e-05 23.3 0.9 3.5 3 0 0 3 3 3 1 TPR repeat MIT PF04212.13 CAM71004.1 - 0.018 14.9 5.0 0.059 13.2 1.1 2.8 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.23 CAM71004.1 - 0.027 14.0 11.1 5.2 6.8 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 CAM71004.1 - 0.081 12.8 8.5 0.23 11.4 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3292 PF11696.3 CAM71004.1 - 0.11 10.3 2.6 0.21 9.4 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) TPR_2 PF07719.12 CAM71004.1 - 0.22 11.5 15.0 1.1 9.2 0.3 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Tweety PF04906.8 CAM71004.1 - 1.1 7.5 0.0 2 6.7 0.0 1.3 1 0 0 1 1 1 0 Tweety TPR_7 PF13176.1 CAM71004.1 - 3.3 7.7 10.4 5 7.1 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Nol1_Nop2_Fmu PF01189.12 CAM71006.1 - 3.6e-24 85.6 0.0 5.5e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 CAM71006.1 - 3.8e-05 23.7 0.2 0.00011 22.2 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAM71006.1 - 0.0032 18.0 0.0 0.0088 16.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.15 CAM71006.1 - 0.18 10.7 0.0 0.36 9.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NUDIX PF00293.23 CAM71007.1 - 2e-06 27.4 0.0 6.7e-06 25.7 0.0 1.8 1 1 1 2 2 2 1 NUDIX domain PAP_assoc PF03828.14 CAM71008.1 - 2.6e-08 33.6 0.0 4.8e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 CAM71008.1 - 0.00093 19.4 0.0 0.0017 18.6 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain TPR_14 PF13428.1 CAM71011.1 - 1.8e-05 24.9 51.4 0.18 12.5 0.8 12.0 11 2 2 13 13 13 5 Tetratricopeptide repeat PRP1_N PF06424.7 CAM71011.1 - 0.00068 19.9 1.1 0.0016 18.7 0.8 1.6 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_17 PF13431.1 CAM71011.1 - 0.0019 18.2 0.3 4.8 7.6 0.0 4.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 CAM71011.1 - 0.0029 17.4 1.7 0.0029 17.4 1.2 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 CAM71011.1 - 0.01 15.9 2.9 0.63 10.2 0.1 4.0 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 CAM71011.1 - 0.016 14.7 1.3 0.25 11.0 1.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 CAM71011.1 - 1.5 8.5 20.4 0.092 12.4 0.6 5.8 8 0 0 8 8 8 0 TPR repeat cNMP_binding PF00027.24 CAM71015.1 - 5e-12 45.4 0.0 2.5e-05 24.0 0.0 4.3 3 1 0 3 3 3 3 Cyclic nucleotide-binding domain HD PF01966.17 CAM71016.1 - 3.4e-07 30.2 0.1 1e-06 28.7 0.0 2.0 1 0 0 1 1 1 1 HD domain A_deaminase PF00962.17 CAM71017.1 - 3e-78 263.0 0.1 1.3e-58 198.4 0.0 2.3 2 0 0 2 2 2 2 Adenosine/AMP deaminase DUF1192 PF06698.6 CAM71017.1 - 0.05 13.4 0.1 0.19 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF4603 PF15376.1 CAM71017.1 - 0.083 10.0 0.0 0.12 9.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) DUF972 PF06156.8 CAM71017.1 - 0.089 13.1 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) 7TMR-HDED PF07697.6 CAM71019.1 - 0.034 13.8 0.1 0.071 12.8 0.1 1.5 1 0 0 1 1 1 0 7TM-HD extracellular WD40 PF00400.27 CAM71020.1 - 1.2e-05 25.0 0.8 8.1 6.4 0.0 5.3 5 1 0 5 5 5 3 WD domain, G-beta repeat CHCH PF06747.8 CAM71021.1 - 0.027 14.3 3.1 0.044 13.7 2.2 1.4 1 0 0 1 1 1 0 CHCH domain DUF1903 PF08991.5 CAM71021.1 - 0.08 13.1 1.6 0.13 12.4 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1903) PHD_3 PF13922.1 CAM71023.1 - 0.55 10.5 6.3 0.11 12.7 0.5 2.8 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx Complex1_LYR_2 PF13233.1 CAM71024.1 - 3.4e-09 37.1 5.1 6e-09 36.3 3.5 1.6 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 CAM71024.1 - 0.0022 17.7 0.7 0.006 16.3 0.5 1.7 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CAM71024.1 - 0.007 16.5 0.5 0.017 15.3 0.3 1.7 1 1 0 1 1 1 1 Complex1_LYR-like DUF2456 PF10445.4 CAM71024.1 - 0.07 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2456) Sod_Fe_C PF02777.13 CAM71025.1 - 1.9e-32 111.2 1.2 4.3e-32 110.0 0.8 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 CAM71025.1 - 3.5e-19 68.8 0.2 3.5e-19 68.8 0.2 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Cys_Met_Meta_PP PF01053.15 CAM71026.1 - 2.4e-87 292.7 0.0 2.8e-87 292.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 CAM71026.1 - 1.2e-06 27.6 0.1 1.9e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 CAM71026.1 - 0.0054 15.5 0.0 0.0083 14.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 CAM71026.1 - 0.0056 15.7 0.0 0.011 14.7 0.0 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 CAM71026.1 - 0.021 13.9 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase SpoU_methylase PF00588.14 CAM71027.1 - 1.1e-24 86.8 0.0 3.1e-23 82.2 0.0 3.3 4 0 0 4 4 4 1 SpoU rRNA Methylase family Aa_trans PF01490.13 CAM71028.1 - 4.3e-52 176.9 29.9 5.3e-52 176.6 20.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CAM71028.1 - 3.1e-10 39.4 11.0 4.3e-10 38.9 6.9 1.7 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family IATP PF04568.7 CAM71030.1 - 2.8 8.0 0.0 2.8 8.0 0.0 2.8 2 1 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Ribosomal_L27e PF01777.13 CAM71031.1 - 6.9e-27 93.4 1.5 9.1e-27 93.0 1.0 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 CAM71031.1 - 1.2e-05 24.8 0.3 2.9e-05 23.6 0.2 1.7 1 0 0 1 1 1 1 KOW motif Ribonuclease_P PF00825.13 CAM71031.1 - 0.06 13.2 2.3 0.09 12.6 1.6 1.7 1 1 0 1 1 1 0 Ribonuclease P Ribosomal_L27e PF01777.13 CAM71033.1 - 6.9e-27 93.4 1.5 9.1e-27 93.0 1.0 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 CAM71033.1 - 1.2e-05 24.8 0.3 2.9e-05 23.6 0.2 1.7 1 0 0 1 1 1 1 KOW motif Ribonuclease_P PF00825.13 CAM71033.1 - 0.06 13.2 2.3 0.09 12.6 1.6 1.7 1 1 0 1 1 1 0 Ribonuclease P Sybindin PF04099.7 CAM71034.1 - 4.3e-22 78.3 0.0 5e-22 78.1 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 CAM71034.1 - 8.9e-09 35.3 0.0 9.2e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Rhodanese PF00581.15 CAM71036.1 - 2.8e-07 30.8 0.0 3.4e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Sec7 PF01369.15 CAM71037.1 - 2.2e-27 95.9 0.0 3.6e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 CAM71037.1 - 1.4e-14 53.8 0.0 3.8e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF4140 PF13600.1 CAM71038.1 - 0.013 15.9 7.7 0.021 15.2 1.7 2.9 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF3138 PF11336.3 CAM71038.1 - 4.1 5.4 8.1 9.1 4.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) RNase_T PF00929.19 CAM71041.1 - 8.9e-15 55.3 0.0 8.1e-14 52.2 0.0 1.9 1 1 0 1 1 1 1 Exonuclease RRM_6 PF14259.1 CAM71043.1 - 7e-21 73.9 0.1 7.2e-10 38.7 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAM71043.1 - 7.5e-21 73.5 0.1 7e-07 28.7 0.0 4.1 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM71043.1 - 3.8e-06 26.6 0.0 1.2e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RPN7 PF10602.4 CAM71044.1 - 1e-48 165.0 0.0 1.7e-48 164.3 0.0 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 CAM71044.1 - 3.3e-16 59.4 0.3 9.2e-16 58.0 0.0 1.9 3 0 0 3 3 3 1 PCI domain Prefoldin PF02996.12 CAM71046.1 - 1.6e-09 37.4 0.2 2.9e-09 36.6 0.1 1.5 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 CAM71046.1 - 2.6e-05 23.8 1.5 0.011 15.4 0.1 2.4 2 0 0 2 2 2 2 Prefoldin subunit zf-C4H2 PF10146.4 CAM71046.1 - 5.1 7.0 14.0 0.37 10.7 0.1 3.1 3 0 0 3 3 3 0 Zinc finger-containing protein TPR_11 PF13414.1 CAM71047.1 - 1e-20 73.1 15.0 8.4e-12 44.5 0.4 4.6 4 0 0 4 4 4 3 TPR repeat TPR_16 PF13432.1 CAM71047.1 - 2.1e-10 40.9 0.9 1.8e-09 38.0 0.3 5.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 CAM71047.1 - 2e-09 36.6 19.2 0.04 13.8 0.1 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 CAM71047.1 - 4e-09 35.6 16.6 0.12 12.0 0.1 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat CS PF04969.11 CAM71047.1 - 1.1e-08 35.4 0.1 3.2e-08 34.0 0.0 1.8 2 0 0 2 2 2 1 CS domain TPR_19 PF14559.1 CAM71047.1 - 3.7e-07 30.3 12.4 8.7e-06 25.9 0.4 4.7 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CAM71047.1 - 7.6e-05 23.0 24.6 0.11 13.1 0.0 7.7 5 2 2 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 CAM71047.1 - 0.003 17.6 11.4 0.4 10.8 0.2 4.1 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 CAM71047.1 - 0.0096 15.7 6.9 4.1 7.3 0.0 4.3 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat DUF4427 PF14468.1 CAM71047.1 - 0.016 14.9 1.2 7.1 6.3 0.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4427) TPR_9 PF13371.1 CAM71047.1 - 0.024 14.4 12.0 7.8 6.4 0.1 5.8 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 CAM71047.1 - 0.096 12.6 25.4 0.17 11.8 0.9 5.6 5 2 1 6 6 6 0 Tetratricopeptide repeat TPPII_N PF12583.3 CAM71047.1 - 0.27 11.3 0.1 0.27 11.3 0.0 3.0 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal TPR_7 PF13176.1 CAM71047.1 - 2 8.3 19.0 21 5.2 0.1 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat FYVE PF01363.16 CAM71048.1 - 0.0063 16.3 13.6 0.016 15.1 9.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger DUF778 PF05608.7 CAM71050.1 - 1e-51 174.4 0.0 1.3e-51 174.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF778) SNAP PF14938.1 CAM71052.1 - 8.4e-55 185.8 20.2 9.8e-55 185.6 14.0 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 CAM71052.1 - 2.1e-05 24.3 8.6 0.014 15.2 1.5 3.1 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CAM71052.1 - 0.00043 20.6 19.7 2.4 9.0 0.2 5.5 4 1 2 6 6 5 3 Tetratricopeptide repeat Foie-gras_1 PF11817.3 CAM71052.1 - 0.0022 17.5 7.0 0.0057 16.1 4.9 1.7 1 1 0 1 1 1 1 Foie gras liver health family 1 TPR_19 PF14559.1 CAM71052.1 - 0.026 14.8 12.3 0.78 10.1 1.3 3.3 1 1 2 3 3 3 0 Tetratricopeptide repeat DUF410 PF04190.8 CAM71052.1 - 0.033 13.7 4.8 0.047 13.2 1.0 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF410) TPR_7 PF13176.1 CAM71052.1 - 0.055 13.2 7.7 12 6.0 0.1 5.1 3 1 2 5 5 5 0 Tetratricopeptide repeat PPR_3 PF13812.1 CAM71052.1 - 0.13 12.6 7.8 10 6.6 0.1 4.2 4 0 0 4 4 4 0 Pentatricopeptide repeat domain DUF1024 PF06260.7 CAM71052.1 - 0.16 12.1 4.1 7.5 6.7 0.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1024) TPR_16 PF13432.1 CAM71052.1 - 0.32 11.7 14.2 4.4 8.1 2.2 3.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CAM71052.1 - 2.9 8.5 18.0 10 6.8 0.9 5.7 3 1 2 5 5 5 0 Tetratricopeptide repeat UCH PF00443.24 CAM71054.1 - 2.3e-51 174.4 0.0 4.3e-51 173.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CAM71054.1 - 1.7e-20 73.6 1.0 1.9e-12 47.2 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Mt_ATP-synt_B PF05405.9 CAM71054.1 - 0.069 12.5 0.1 11 5.4 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) FG-GAP PF01839.18 CAM71055.1 - 0.00031 20.3 0.1 0.0011 18.5 0.0 2.0 1 0 0 1 1 1 1 FG-GAP repeat VCBS PF13517.1 CAM71055.1 - 0.031 14.6 0.4 0.11 12.8 0.0 2.2 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PQQ PF01011.16 CAM71055.1 - 0.052 13.1 1.1 0.63 9.6 0.0 3.0 3 0 0 3 3 3 0 PQQ enzyme repeat TTL PF03133.10 CAM71056.1 - 2.3e-70 236.8 0.0 1.3e-57 195.0 0.0 2.1 1 1 1 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 CAM71056.1 - 5.8e-05 22.0 0.0 0.013 14.3 0.0 2.2 2 0 0 2 2 2 2 YheC/D like ATP-grasp DUF1738 PF08401.6 CAM71057.1 - 0.00032 20.4 0.0 4.8 6.9 0.0 3.3 3 0 0 3 3 3 3 Domain of unknown function (DUF1738) NDK PF00334.14 CAM71058.1 - 1.8e-57 192.8 0.0 2.1e-57 192.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase NDK PF00334.14 CAM71059.1 - 1.8e-57 192.8 0.0 2.1e-57 192.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase MCM PF00493.18 CAM71060.1 - 1.9e-126 421.3 0.0 2.6e-126 420.9 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CAM71060.1 - 9.8e-13 48.6 0.0 2.3e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 CAM71060.1 - 5.8e-07 28.8 0.0 8.5e-05 21.7 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CAM71060.1 - 6.1e-06 26.0 0.0 3.7e-05 23.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CAM71060.1 - 0.013 15.0 0.0 0.037 13.6 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HisKA PF00512.20 CAM71060.1 - 0.062 13.3 0.3 15 5.6 0.0 2.7 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain Sigma54_activat PF00158.21 CAM71060.1 - 0.1 12.0 0.0 0.77 9.2 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain TBCA PF02970.11 CAM71061.1 - 2.3e-22 78.8 2.1 2.8e-22 78.5 1.4 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A FH2 PF02181.18 CAM71061.1 - 0.064 12.1 0.4 0.072 11.9 0.3 1.0 1 0 0 1 1 1 0 Formin Homology 2 Domain EIAV_Rev PF11129.3 CAM71061.1 - 0.082 12.9 0.7 0.27 11.2 0.2 1.8 1 1 1 2 2 2 0 Rev protein of equine infectious anaemia virus TMF_TATA_bd PF12325.3 CAM71061.1 - 0.1 12.3 1.8 0.17 11.6 1.0 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Pox_A_type_inc PF04508.7 CAM71061.1 - 2.1 8.3 6.8 18 5.4 0.1 3.2 2 1 1 3 3 3 0 Viral A-type inclusion protein repeat Phosducin PF02114.11 CAM71062.1 - 1.4e-10 40.4 0.1 1.5e-10 40.2 0.1 1.0 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 CAM71062.1 - 3.4e-08 33.0 0.0 5.1e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.1 CAM71062.1 - 0.019 14.7 0.0 0.048 13.4 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin domain Adeno_100 PF02438.11 CAM71062.1 - 0.087 11.0 0.1 0.12 10.5 0.0 1.1 1 0 0 1 1 1 0 Late 100kD protein DIM1 PF02966.11 CAM71062.1 - 0.11 12.0 0.5 0.53 9.8 0.0 2.1 1 1 1 2 2 2 0 Mitosis protein DIM1 Rab5ip PF07019.7 CAM71065.1 - 1.1e-20 73.4 5.5 1.4e-20 73.2 3.8 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) PTR2 PF00854.16 CAM71065.1 - 0.013 14.2 3.1 0.015 14.0 2.1 1.1 1 0 0 1 1 1 0 POT family FA_desaturase PF00487.19 CAM71065.1 - 0.33 10.3 2.3 0.42 10.0 1.6 1.3 1 1 0 1 1 1 0 Fatty acid desaturase DUF21 PF01595.15 CAM71067.1 - 9.2e-30 103.2 8.4 1.4e-29 102.6 5.8 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 L_HGMIC_fpl PF10242.4 CAM71067.1 - 9 6.2 11.1 55 3.6 7.7 2.1 1 1 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein LRR_4 PF12799.2 CAM71068.1 - 7.3e-22 76.5 11.6 1.1e-08 34.5 1.5 3.6 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM71068.1 - 3.7e-09 36.1 7.9 0.00014 21.4 2.2 3.2 1 1 3 4 4 4 3 Leucine rich repeat LRR_6 PF13516.1 CAM71068.1 - 3.9e-06 26.3 8.9 2.2 8.6 0.5 5.5 3 1 2 5 5 5 3 Leucine Rich repeat LRR_9 PF14580.1 CAM71068.1 - 1.3e-05 24.8 0.1 0.00021 20.9 0.0 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.28 CAM71068.1 - 2.3e-05 23.8 7.6 2.2 8.6 0.2 6.1 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_7 PF13504.1 CAM71068.1 - 7.7e-05 22.2 2.2 1.7 9.1 0.0 5.1 5 0 0 5 5 5 2 Leucine rich repeat MMR_HSR1 PF01926.18 CAM71069.1 - 4.4e-11 42.7 0.0 8.5e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CAM71069.1 - 1.5e-05 24.2 0.0 3.9e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 CAM71069.1 - 0.0013 18.2 0.0 0.31 10.4 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 CAM71069.1 - 0.01 15.8 1.4 0.022 14.7 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain Miro PF08477.8 CAM71069.1 - 0.014 15.8 0.0 0.042 14.3 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein ABC_tran PF00005.22 CAM71069.1 - 0.028 14.7 0.0 0.085 13.1 0.0 1.8 1 0 0 1 1 1 0 ABC transporter DnaJ PF00226.26 CAM71070.1 - 2.6e-20 71.9 0.0 5.3e-20 70.9 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Angiomotin_C PF12240.3 CAM71070.1 - 0.16 11.4 6.7 0.37 10.2 4.7 1.7 1 1 0 1 1 1 0 Angiomotin C terminal Metallophos PF00149.23 CAM71071.1 - 8.2e-43 146.1 0.1 1e-42 145.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ras PF00071.17 CAM71072.1 - 1.1e-11 44.3 0.1 2.4e-11 43.2 0.0 1.5 1 1 0 1 1 1 1 Ras family Miro PF08477.8 CAM71072.1 - 1e-06 29.2 0.0 2.3e-06 28.1 0.0 1.6 1 1 0 1 1 1 1 Miro-like protein IBR PF01485.16 CAM71072.1 - 0.00021 21.1 0.1 0.00046 20.0 0.0 1.5 1 0 0 1 1 1 1 IBR domain Gtr1_RagA PF04670.7 CAM71072.1 - 0.00038 19.6 0.1 0.00065 18.9 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region YdjO PF14169.1 CAM71072.1 - 0.012 15.0 0.1 0.026 13.9 0.1 1.5 1 0 0 1 1 1 0 Cold-inducible protein YdjO zf-MIZ PF02891.15 CAM71075.1 - 3.3e-10 39.3 6.6 6.3e-10 38.4 4.6 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 CAM71075.1 - 9.1e-06 25.1 2.4 1.4e-05 24.4 1.0 1.9 2 1 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit DUF2072 PF09845.4 CAM71075.1 - 0.077 12.9 0.1 0.19 11.6 0.1 1.7 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) DZR PF12773.2 CAM71075.1 - 0.099 12.4 0.2 0.099 12.4 0.1 2.3 2 0 0 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.6 CAM71075.1 - 1.6 8.4 4.4 1.3 8.7 1.4 1.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-NADH-PPase PF09297.6 CAM71075.1 - 1.9 8.0 9.9 0.24 10.9 3.2 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain ABC_tran PF00005.22 CAM71076.1 - 6.2e-35 120.4 0.0 2.2e-34 118.6 0.0 1.9 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 CAM71076.1 - 1.7e-23 83.4 6.6 2.2e-23 83.0 4.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 CAM71076.1 - 1e-05 25.6 0.4 0.0039 17.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 CAM71076.1 - 1.5e-05 24.3 0.4 0.0023 17.2 0.3 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CAM71076.1 - 0.00047 19.6 1.2 0.0019 17.6 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CAM71076.1 - 0.0037 17.4 0.1 0.032 14.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CAM71076.1 - 0.0038 17.2 0.0 0.0077 16.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 CAM71076.1 - 0.0081 15.3 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 CAM71076.1 - 0.017 15.9 0.0 0.05 14.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 CAM71076.1 - 0.019 15.2 0.3 0.16 12.3 0.2 2.1 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.1 CAM71076.1 - 0.022 14.6 0.0 0.06 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Pox_A31 PF05771.6 CAM71076.1 - 0.022 14.5 0.1 0.052 13.3 0.1 1.6 1 0 0 1 1 1 0 Poxvirus A31 protein MobB PF03205.9 CAM71076.1 - 0.03 14.0 0.0 0.068 12.8 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 CAM71076.1 - 0.039 14.2 0.0 0.34 11.2 0.0 2.5 2 1 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.18 CAM71076.1 - 0.073 13.0 0.1 0.43 10.5 0.0 2.3 3 0 0 3 3 3 0 50S ribosome-binding GTPase HisKA_3 PF07730.8 CAM71078.1 - 4 7.8 8.2 0.93 9.8 0.1 3.2 3 1 0 3 3 3 0 Histidine kinase FSH1 PF03959.8 CAM71079.1 - 1.9e-29 102.6 0.0 2.8e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) MMR_HSR1_C PF08438.5 CAM71079.1 - 5.4e-25 87.7 0.0 1.2e-24 86.5 0.0 1.7 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 CAM71079.1 - 7.6e-14 51.6 0.0 2e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RWD PF05773.17 CAM71079.1 - 0.00018 21.3 0.0 0.00073 19.4 0.0 2.0 2 0 0 2 2 2 1 RWD domain Abhydrolase_5 PF12695.2 CAM71079.1 - 0.00019 21.2 1.7 0.00042 20.0 0.2 2.4 3 0 0 3 3 3 1 Alpha/beta hydrolase family FeoB_N PF02421.13 CAM71079.1 - 0.00095 18.4 0.1 0.0099 15.1 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Cutinase PF01083.17 CAM71079.1 - 0.021 14.5 0.1 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Cutinase ArgK PF03308.11 CAM71079.1 - 0.081 11.6 0.3 0.49 9.1 0.1 2.0 2 0 0 2 2 2 0 ArgK protein ATP_bind_1 PF03029.12 CAM71079.1 - 0.084 12.3 0.0 3.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 CAM71079.1 - 0.19 11.1 0.0 11 5.4 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Ribosomal_L3 PF00297.17 CAM71080.1 - 7.4e-101 336.9 9.6 9.2e-101 336.6 6.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 Ribosomal_L3 PF00297.17 CAM71081.1 - 3.2e-100 334.8 9.5 3.9e-100 334.5 6.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 Aldedh PF00171.17 CAM71082.1 - 1.6e-18 66.3 1.8 1.7e-14 53.0 0.2 2.2 2 0 0 2 2 2 2 Aldehyde dehydrogenase family YadA_anchor PF03895.10 CAM71082.1 - 3.1 7.8 7.8 0.91 9.5 0.2 3.4 3 0 0 3 3 3 0 YadA-like C-terminal region IQ PF00612.22 CAM71083.1 - 3e-27 91.5 107.4 8e-06 25.0 3.5 12.7 11 0 0 11 11 11 11 IQ calmodulin-binding motif LRR_4 PF12799.2 CAM71084.1 - 4.5e-10 38.9 1.2 1.1e-06 28.1 0.7 3.6 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CAM71084.1 - 2.2e-08 33.3 2.9 0.0017 18.2 0.2 4.5 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.28 CAM71084.1 - 1.4e-05 24.4 1.3 0.35 11.0 0.0 5.0 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_7 PF13504.1 CAM71084.1 - 0.003 17.4 3.1 4 8.0 0.1 5.1 5 0 0 5 5 5 1 Leucine rich repeat LRR_8 PF13855.1 CAM71084.1 - 0.01 15.6 2.6 0.026 14.2 0.8 2.3 2 0 0 2 2 2 1 Leucine rich repeat L51_S25_CI-B8 PF05047.11 CAM71085.1 - 0.0056 16.3 0.1 0.0085 15.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF2738 PF10927.3 CAM71085.1 - 0.041 12.9 0.0 0.063 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2738) AbbA_antirepres PF14156.1 CAM71086.1 - 0.071 12.7 0.1 0.26 10.9 0.0 1.9 1 0 0 1 1 1 0 Antirepressor AbbA COG5 PF10392.4 CAM71087.1 - 2.5e-13 50.1 17.7 6.2e-13 48.8 2.2 3.7 3 0 0 3 3 3 2 Golgi transport complex subunit 5 DUF1664 PF07889.7 CAM71087.1 - 0.0064 16.2 2.0 0.012 15.4 0.4 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) PRT_C PF08372.5 CAM71088.1 - 0.36 10.3 2.0 1.1 8.7 0.1 2.5 3 0 0 3 3 3 0 Plant phosphoribosyltransferase C-terminal Miro PF08477.8 CAM71089.1 - 2.8e-06 27.8 0.0 4.7e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAM71089.1 - 4.2e-06 26.1 0.1 0.00033 19.9 0.1 2.3 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CAM71089.1 - 7.1e-06 25.9 0.0 1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 CAM71089.1 - 1.4e-05 24.5 0.0 3.7e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 Ras family GTP_EFTU PF00009.22 CAM71089.1 - 0.00042 19.7 0.0 0.00063 19.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 CAM71089.1 - 0.00067 20.4 0.0 0.0013 19.5 0.0 1.5 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.15 CAM71089.1 - 0.0015 17.2 0.1 0.97 8.0 0.0 2.1 1 1 0 2 2 2 2 G-protein alpha subunit PduV-EutP PF10662.4 CAM71089.1 - 0.0044 16.4 0.0 0.0086 15.5 0.0 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 CAM71089.1 - 0.019 14.1 0.2 0.044 13.0 0.1 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CAM71089.1 - 0.032 13.3 0.0 0.25 10.4 0.0 2.3 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region Dynamin_N PF00350.18 CAM71089.1 - 0.098 12.4 0.2 0.17 11.6 0.1 1.5 1 1 0 1 1 1 0 Dynamin family AAA_18 PF13238.1 CAM71089.1 - 0.1 12.8 0.1 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 CAM71089.1 - 0.12 11.2 0.1 0.16 10.8 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein YlqD PF11068.3 CAM71090.1 - 0.14 12.1 1.4 0.34 10.9 1.0 1.5 1 1 0 1 1 1 0 YlqD protein AAA_16 PF13191.1 CAM71091.1 - 1.1e-05 25.5 0.1 2.6e-05 24.2 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain G-alpha PF00503.15 CAM71091.1 - 4.8e-05 22.2 0.0 0.00074 18.3 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit DUF258 PF03193.11 CAM71091.1 - 0.00013 21.2 0.0 0.00026 20.2 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CAM71091.1 - 0.00018 21.6 0.2 0.023 14.8 0.1 2.7 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 CAM71091.1 - 0.00045 20.6 0.0 0.0096 16.4 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 CAM71091.1 - 0.00057 19.3 0.0 0.68 9.3 0.0 2.6 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain NACHT PF05729.7 CAM71091.1 - 0.0019 17.9 0.1 0.0064 16.1 0.0 1.8 2 0 0 2 2 2 1 NACHT domain ABC_tran PF00005.22 CAM71091.1 - 0.0029 17.9 0.1 0.0057 16.9 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_33 PF13671.1 CAM71091.1 - 0.0039 17.0 1.0 0.013 15.3 0.1 2.0 1 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CAM71091.1 - 0.0044 16.5 0.1 0.012 15.0 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 CAM71091.1 - 0.0057 15.7 0.0 0.013 14.5 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin Pox_A32 PF04665.7 CAM71091.1 - 0.009 15.3 0.0 0.027 13.7 0.0 1.7 2 0 0 2 2 2 1 Poxvirus A32 protein cobW PF02492.14 CAM71091.1 - 0.011 15.2 0.3 0.083 12.3 0.2 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 CAM71091.1 - 0.014 14.9 0.7 0.81 9.1 0.3 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Arf PF00025.16 CAM71091.1 - 0.022 13.9 0.0 0.16 11.2 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_19 PF13245.1 CAM71091.1 - 0.037 13.7 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain NB-ARC PF00931.17 CAM71091.1 - 0.038 12.8 0.0 0.065 12.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DAP3 PF10236.4 CAM71091.1 - 0.041 12.8 0.0 0.066 12.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_24 PF13479.1 CAM71091.1 - 0.067 12.7 0.1 2.3 7.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CAM71091.1 - 0.068 12.8 0.0 0.18 11.4 0.0 1.8 1 1 0 1 1 1 0 Archaeal ATPase SRPRB PF09439.5 CAM71091.1 - 0.085 12.0 0.1 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Ras PF00071.17 CAM71091.1 - 0.093 12.1 0.0 0.77 9.1 0.0 2.2 2 0 0 2 2 2 0 Ras family IstB_IS21 PF01695.12 CAM71091.1 - 0.099 12.0 0.1 5.2 6.4 0.0 2.6 3 0 0 3 3 2 0 IstB-like ATP binding protein MobB PF03205.9 CAM71091.1 - 0.13 11.9 0.1 0.32 10.6 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B TGF_beta_GS PF08515.7 CAM71091.1 - 0.39 10.0 5.7 1.9 7.9 0.0 2.4 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif Pkinase PF00069.20 CAM71093.1 - 7.1e-73 244.9 0.0 1e-72 244.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM71093.1 - 6.2e-35 120.5 0.0 2.3e-34 118.6 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 CAM71093.1 - 0.0014 17.9 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 CAM71093.1 - 0.0018 17.2 0.0 0.0037 16.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 CAM71093.1 - 0.038 12.8 0.0 0.062 12.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Glucosamine_iso PF01182.15 CAM71094.1 - 1.6e-22 80.2 0.0 2.3e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Cpn60_TCP1 PF00118.19 CAM71095.1 - 2.3e-136 455.2 6.8 2.6e-136 455.1 4.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CTDII PF01556.13 CAM71098.1 - 3.1e-22 78.2 0.0 5.9e-21 74.1 0.0 2.4 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ PF00226.26 CAM71098.1 - 1.1e-17 63.5 5.6 1.8e-17 62.7 3.9 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 CAM71098.1 - 1.3e-13 50.8 13.1 2e-13 50.1 9.1 1.3 1 0 0 1 1 1 1 DnaJ central domain Arabinose_Isome PF02610.10 CAM71098.1 - 0.033 13.1 0.3 0.048 12.6 0.2 1.2 1 0 0 1 1 1 0 L-arabinose isomerase NMD3 PF04981.8 CAM71098.1 - 0.15 11.1 4.1 0.78 8.8 0.1 2.4 2 0 0 2 2 2 0 NMD3 family DZR PF12773.2 CAM71098.1 - 0.65 9.8 12.2 54 3.7 8.5 2.3 1 1 0 1 1 1 0 Double zinc ribbon A2L_zn_ribbon PF08792.5 CAM71098.1 - 1.1 8.8 13.5 1.4 8.4 0.0 3.3 3 1 1 4 4 4 0 A2L zinc ribbon domain DUF3797 PF12677.2 CAM71098.1 - 2.7 7.6 6.1 40 3.9 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF3797) Pyr_redox_2 PF07992.9 CAM71099.1 - 3.2e-41 141.4 6.2 7.3e-41 140.2 2.9 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 CAM71099.1 - 2.5e-39 133.7 0.3 5.7e-39 132.5 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 CAM71099.1 - 3.2e-20 72.3 11.1 1.6e-18 66.8 1.4 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CAM71099.1 - 8.1e-11 42.3 0.5 1.8e-06 28.1 0.1 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CAM71099.1 - 3.7e-10 39.4 14.1 5.6e-10 38.8 1.0 2.9 3 1 0 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.17 CAM71099.1 - 5.1e-10 38.7 2.9 5.1e-10 38.7 2.0 2.9 2 2 1 3 3 3 2 Glucose inhibited division protein A NAD_binding_8 PF13450.1 CAM71099.1 - 1.6e-07 31.2 6.0 0.00011 22.1 0.6 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CAM71099.1 - 7.2e-07 28.3 1.4 7.2e-07 28.3 1.0 4.0 2 1 2 4 4 4 1 FAD binding domain Thi4 PF01946.12 CAM71099.1 - 2.6e-06 26.7 4.9 2.3e-05 23.5 0.5 2.7 1 1 1 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 CAM71099.1 - 6e-06 25.5 12.5 0.031 13.3 0.4 3.2 2 1 1 3 3 3 3 FAD binding domain K_oxygenase PF13434.1 CAM71099.1 - 1.9e-05 23.7 0.3 0.047 12.6 0.0 2.7 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 CAM71099.1 - 0.0003 19.3 1.1 0.0003 19.3 0.8 3.7 3 1 1 4 4 4 1 HI0933-like protein DAO PF01266.19 CAM71099.1 - 0.00032 19.6 19.1 0.063 12.1 1.6 4.1 2 2 1 4 4 4 3 FAD dependent oxidoreductase 3HCDH_N PF02737.13 CAM71099.1 - 0.0008 19.1 0.8 0.0008 19.1 0.6 2.8 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 CAM71099.1 - 0.015 14.8 2.9 0.21 11.1 0.1 2.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.1 CAM71099.1 - 0.025 14.8 0.1 0.49 10.7 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_binding_7 PF13241.1 CAM71099.1 - 0.065 13.4 2.1 0.52 10.5 0.1 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF3879 PF12995.2 CAM71099.1 - 0.065 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3879) DUF2634 PF10934.3 CAM71099.1 - 0.1 12.3 0.2 0.23 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2634) Amino_oxidase PF01593.19 CAM71099.1 - 0.14 11.1 0.2 0.25 10.3 0.2 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 CAM71099.1 - 6.7 5.5 8.5 2.6 6.8 0.4 2.9 2 1 1 3 3 3 0 Lycopene cyclase protein Cyclin_N PF00134.18 CAM71100.1 - 1e-38 131.7 1.2 1e-38 131.7 0.8 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CAM71100.1 - 2.5e-34 117.7 0.3 5.9e-34 116.5 0.0 1.7 2 0 0 2 2 2 1 Cyclin, C-terminal domain TMEMspv1-c74-12 PF11044.3 CAM71101.1 - 0.041 13.4 0.2 0.08 12.5 0.1 1.6 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Na_H_antiporter PF03553.9 CAM71101.1 - 0.078 11.9 0.0 0.093 11.7 0.0 1.0 1 0 0 1 1 1 0 Na+/H+ antiporter family GlnD_UR_UTase PF08335.6 CAM71102.1 - 0.017 14.9 0.1 0.2 11.4 0.1 2.6 1 1 1 2 2 2 0 GlnD PII-uridylyltransferase CH PF00307.26 CAM71102.1 - 0.052 13.5 0.1 15 5.6 0.0 2.8 2 0 0 2 2 2 0 Calponin homology (CH) domain zf-B_box PF00643.19 CAM71103.1 - 9e-07 28.6 3.5 2.3e-06 27.3 2.4 1.7 1 0 0 1 1 1 1 B-box zinc finger DUF3391 PF11871.3 CAM71103.1 - 0.75 10.0 3.0 2.2 8.5 2.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Lipase_3 PF01764.20 CAM71104.1 - 4.1e-13 49.1 0.0 8.1e-12 44.9 0.0 2.4 2 0 0 2 2 2 1 Lipase (class 3) GH97_N PF14508.1 CAM71104.1 - 0.065 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 N-terminal TruD PF01142.13 CAM71106.1 - 1.2e-34 119.6 0.1 1.1e-14 53.9 0.0 4.1 4 0 0 4 4 4 4 tRNA pseudouridine synthase D (TruD) DnaG_DnaB_bind PF08278.6 CAM71106.1 - 0.048 13.8 0.1 4.9 7.3 0.0 2.7 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding zf-MYND PF01753.13 CAM71107.1 - 0.0022 17.7 13.0 0.0022 17.7 9.0 2.5 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.1 CAM71107.1 - 0.17 11.7 10.2 0.13 12.1 5.3 2.1 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Abhydrolase_6 PF12697.2 CAM71108.1 - 3.8e-06 26.9 2.6 1.2e-05 25.3 1.8 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CAM71108.1 - 0.0037 17.0 0.2 0.46 10.2 0.1 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAM71108.1 - 0.0064 16.0 6.0 0.012 15.1 4.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Dopey_N PF04118.9 CAM71109.1 - 3.6e-27 94.9 0.0 7.6e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 Dopey, N-terminal DUF1056 PF06341.6 CAM71110.1 - 0.18 11.8 2.9 0.75 9.8 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1056) UPF0564 PF10595.4 CAM71111.1 - 1.2e-10 40.8 16.3 2.1e-08 33.4 1.1 2.8 2 2 0 2 2 2 2 Uncharacterised protein family UPF0564 DUF4071 PF13281.1 CAM71111.1 - 0.15 10.8 1.7 0.25 10.1 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) zf-C2HC_2 PF13913.1 CAM71113.1 - 1.9e-26 91.1 15.6 3.4e-10 39.3 0.6 3.4 3 0 0 3 3 3 3 zinc-finger of a C2HC-type zf-ribbon_3 PF13248.1 CAM71113.1 - 6.3e-05 22.0 16.6 0.026 13.7 5.6 3.9 3 1 1 4 4 4 2 zinc-ribbon domain zinc_ribbon_2 PF13240.1 CAM71113.1 - 0.0097 15.3 24.6 0.26 10.8 7.6 4.2 4 1 1 5 5 5 3 zinc-ribbon domain zf-CHCC PF10276.4 CAM71113.1 - 0.013 15.2 1.4 0.97 9.3 0.0 3.6 3 0 0 3 3 3 0 Zinc-finger domain Sgf11 PF08209.6 CAM71113.1 - 0.059 12.6 7.4 0.59 9.4 0.2 3.6 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) zf-C2H2 PF00096.21 CAM71113.1 - 0.092 13.1 0.4 0.092 13.1 0.2 4.1 5 0 0 5 5 3 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CAM71113.1 - 0.097 13.0 4.6 15 6.0 0.1 3.6 3 0 0 3 3 3 0 Zinc-finger double domain DZR PF12773.2 CAM71113.1 - 0.2 11.4 19.2 6.3 6.6 9.4 3.8 3 1 0 3 3 3 0 Double zinc ribbon DUF164 PF02591.10 CAM71113.1 - 0.51 10.2 8.2 12 5.8 0.0 3.8 3 1 0 3 3 3 0 Putative zinc ribbon domain NinF PF05810.7 CAM71113.1 - 2.6 7.9 9.5 5.8 6.7 0.2 3.3 3 0 0 3 3 3 0 NinF protein NOB1_Zn_bind PF08772.6 CAM71113.1 - 5.7 6.8 10.9 14 5.5 4.6 2.7 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like RNase_PH PF01138.16 CAM71114.1 - 9.3e-07 29.2 0.0 1.8e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CAM71114.1 - 2.8e-05 23.9 0.0 5.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 RRM_1 PF00076.17 CAM71115.1 - 4.1e-09 35.9 0.0 4.2e-06 26.2 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM71115.1 - 1.4e-06 28.1 0.0 9.3e-05 22.3 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM71115.1 - 0.00011 21.9 0.0 0.0003 20.5 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFMR PF07777.6 CAM71115.1 - 3.1 7.6 10.4 5.7 6.8 7.2 1.4 1 0 0 1 1 1 0 G-box binding protein MFMR Ribosomal_60s PF00428.14 CAM71115.1 - 6.7 7.1 13.4 0.71 10.3 2.2 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein TPR_19 PF14559.1 CAM71116.1 - 0.49 10.7 8.1 2.3 8.6 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DEAD PF00270.24 CAM71117.1 - 4e-16 58.9 0.0 9.2e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM71117.1 - 6.5e-06 25.9 0.0 7.1e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAM71117.1 - 0.00096 19.0 0.0 0.0028 17.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CAM71117.1 - 0.0048 17.0 0.6 6.1 6.9 0.0 3.5 3 1 1 4 4 4 2 AAA domain AAA PF00004.24 CAM71117.1 - 0.0076 16.4 0.0 0.45 10.7 0.0 3.2 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 CAM71117.1 - 0.012 15.0 0.1 0.13 11.7 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.11 CAM71117.1 - 0.034 13.3 0.0 0.059 12.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Robl_LC7 PF03259.12 CAM71120.1 - 2.1e-08 33.6 0.2 4.4e-07 29.3 0.0 2.1 1 1 0 2 2 2 2 Roadblock/LC7 domain Nol1_Nop2_Fmu PF01189.12 CAM71122.1 - 0.0013 18.1 0.1 0.0028 17.1 0.0 1.4 1 0 0 1 1 1 1 NOL1/NOP2/sun family UPF0104 PF03706.8 CAM71123.1 - 0.051 12.8 1.1 0.063 12.5 0.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) HlyD PF00529.15 CAM71124.1 - 3.4 6.8 11.3 6.4 5.9 7.9 1.5 1 1 0 1 1 1 0 HlyD family secretion protein PH PF00169.24 CAM71126.1 - 0.021 15.0 0.0 0.036 14.2 0.0 1.5 1 1 0 1 1 1 0 PH domain PH_6 PF15406.1 CAM71126.1 - 0.072 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain DUF3208 PF11482.3 CAM71128.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3208) ECH_C PF13766.1 CAM71129.1 - 5.7e-23 81.2 0.0 8.5e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 CAM71129.1 - 1.1e-13 50.8 0.0 1.7e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 CAM71130.1 - 1.1e-22 80.3 0.0 1.7e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 CAM71130.1 - 1.2e-13 50.8 0.0 1.7e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 CAM71131.1 - 6.8e-30 103.6 0.1 1e-29 103.0 0.1 1.3 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 CAM71131.1 - 2.5e-23 82.4 0.0 4.1e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family zf-ribbon_3 PF13248.1 CAM71132.1 - 0.0014 17.7 1.1 0.0034 16.5 0.7 1.7 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 CAM71132.1 - 0.0041 16.5 1.0 0.0086 15.5 0.7 1.5 1 0 0 1 1 1 1 zinc-ribbon domain zf-4CXXC_R1 PF10497.4 CAM71134.1 - 0.032 14.3 0.3 0.054 13.6 0.2 1.4 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 BT1 PF03092.11 CAM71135.1 - 4.6e-29 101.3 15.7 6.9e-29 100.8 10.9 1.2 1 0 0 1 1 1 1 BT1 family TMEM18 PF14770.1 CAM71136.1 - 1.2e-31 108.8 0.7 1.5e-31 108.4 0.5 1.1 1 0 0 1 1 1 1 Transmembrane protein 18 TYW3 PF02676.9 CAM71138.1 - 1.4e-33 115.7 0.0 1.8e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 Mid1 PF12929.2 CAM71138.1 - 0.085 11.5 0.4 0.11 11.2 0.3 1.1 1 0 0 1 1 1 0 Stretch-activated Ca2+-permeable channel component DUF4404 PF14357.1 CAM71139.1 - 0.014 15.8 0.6 0.74 10.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Phage_30_3 PF08010.6 CAM71140.1 - 0.02 14.3 0.3 0.027 13.9 0.2 1.3 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 DUF3106 PF11304.3 CAM71140.1 - 0.19 12.1 8.4 0.24 11.8 5.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3106) MAT_Alpha1 PF04769.7 CAM71141.1 - 9.6e-05 21.7 3.2 0.00012 21.4 2.2 1.2 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 CKS PF01111.14 CAM71142.1 - 7e-39 131.5 0.8 8.5e-39 131.2 0.6 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit TPR_1 PF00515.23 CAM71143.1 - 7.6e-07 28.4 1.6 0.048 13.2 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 CAM71143.1 - 9.1e-07 28.4 7.1 0.00012 21.6 0.2 2.7 2 1 1 3 3 3 2 TPR repeat TPR_12 PF13424.1 CAM71143.1 - 7.4e-06 25.8 3.8 0.00034 20.4 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 CAM71143.1 - 8e-06 25.3 6.7 0.038 13.9 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 CAM71143.1 - 0.0029 17.2 0.1 0.79 9.6 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 CAM71143.1 - 0.94 9.3 9.4 2.7 7.9 1.3 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CAM71143.1 - 6.8 7.3 10.3 9.3 6.9 0.2 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat SHQ1 PF04925.10 CAM71144.1 - 3.9e-51 173.2 0.1 8.8e-51 172.0 0.0 1.5 2 0 0 2 2 2 1 SHQ1 protein WD40 PF00400.27 CAM71145.1 - 0.0018 18.0 3.0 10 6.1 0.0 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat Pox_P21 PF05313.7 CAM71146.1 - 0.00032 20.0 0.5 0.00032 20.0 0.4 2.1 2 1 0 2 2 2 1 Poxvirus P21 membrane protein Cornichon PF03311.9 CAM71146.1 - 0.00032 20.8 7.7 0.00032 20.8 5.4 1.4 2 0 0 2 2 2 1 Cornichon protein DUF4212 PF13937.1 CAM71146.1 - 0.041 13.8 3.1 0.041 13.8 2.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4212) Tic20 PF09685.5 CAM71146.1 - 1.1 9.2 15.1 3.5 7.6 2.0 2.1 2 0 0 2 2 2 0 Tic20-like protein Chromate_transp PF02417.10 CAM71146.1 - 1.6 8.2 13.5 0.16 11.5 4.5 2.5 1 1 2 3 3 3 0 Chromate transporter DUF4064 PF13273.1 CAM71146.1 - 2.8 8.1 9.9 0.13 12.3 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Cornichon PF03311.9 CAM71147.1 - 9e-16 58.1 2.5 9e-16 58.1 1.7 1.6 1 1 0 1 1 1 1 Cornichon protein Mod_r PF07200.8 CAM71148.1 - 0.0022 17.9 7.0 0.022 14.6 1.7 2.2 2 0 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein HAUS-augmin3 PF14932.1 CAM71148.1 - 0.013 14.7 4.6 0.17 11.0 0.0 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Spc7 PF08317.6 CAM71148.1 - 0.027 13.1 2.0 1.7 7.2 0.0 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein bZIP_1 PF00170.16 CAM71148.1 - 0.038 13.9 0.6 0.038 13.9 0.4 2.8 3 1 0 3 3 3 0 bZIP transcription factor FlaC_arch PF05377.6 CAM71148.1 - 0.04 13.8 0.7 3 7.7 0.1 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF3584 PF12128.3 CAM71148.1 - 0.041 11.2 5.5 0.053 10.8 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Myosin_tail_1 PF01576.14 CAM71148.1 - 0.057 11.1 8.9 0.094 10.4 0.1 2.1 2 0 0 2 2 2 0 Myosin tail DUF869 PF05911.6 CAM71148.1 - 0.083 11.1 6.0 0.24 9.5 0.1 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF869) Herpes_BLRF2 PF05812.7 CAM71148.1 - 0.099 12.4 7.4 0.087 12.6 1.4 2.8 3 1 1 4 4 3 0 Herpesvirus BLRF2 protein CENP-Q PF13094.1 CAM71148.1 - 0.11 12.5 13.2 0.33 10.9 0.6 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 CAM71148.1 - 0.15 11.6 12.9 0.36 10.3 0.1 2.1 2 0 0 2 2 2 0 IncA protein ADIP PF11559.3 CAM71148.1 - 0.17 11.7 8.6 4 7.3 0.0 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 CAM71148.1 - 0.21 10.5 6.3 0.18 10.8 1.3 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 NYD-SP28_assoc PF14775.1 CAM71148.1 - 0.22 11.2 6.0 0.15 11.7 0.4 2.5 2 0 0 2 2 2 0 Sperm tail C-terminal domain TBPIP PF07106.8 CAM71148.1 - 0.48 9.9 4.0 2.2 7.7 0.8 2.3 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Med9 PF07544.8 CAM71148.1 - 0.49 10.1 11.6 0.4 10.4 1.0 3.5 4 1 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 HALZ PF02183.13 CAM71148.1 - 0.5 10.1 6.0 3.3 7.4 0.7 3.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF812 PF05667.6 CAM71148.1 - 1.1 7.6 7.8 0.54 8.7 2.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Atg14 PF10186.4 CAM71148.1 - 1.2 8.0 8.0 3.8 6.3 3.7 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1192 PF06698.6 CAM71148.1 - 1.2 8.9 12.4 3.5 7.5 1.1 3.6 4 0 0 4 4 3 0 Protein of unknown function (DUF1192) Spc24 PF08286.6 CAM71148.1 - 1.8 8.2 4.9 1.5 8.5 0.8 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DivIC PF04977.10 CAM71148.1 - 2.3 7.7 6.4 0.97 8.9 1.4 2.4 2 1 0 2 2 2 0 Septum formation initiator Exonuc_VII_S PF02609.11 CAM71148.1 - 2.6 7.8 8.0 1.7 8.5 0.7 2.9 3 0 0 3 3 3 0 Exonuclease VII small subunit DUF972 PF06156.8 CAM71148.1 - 2.7 8.3 8.8 4.5 7.6 1.1 3.1 2 2 1 3 3 3 0 Protein of unknown function (DUF972) SYCE1 PF15233.1 CAM71148.1 - 5.1 7.0 11.5 0.95 9.3 0.2 2.4 2 1 0 2 2 2 0 Synaptonemal complex central element protein 1 Myosin_head PF00063.16 CAM71150.1 - 1.5e-169 565.3 0.0 4.6e-169 563.7 0.0 1.7 1 1 0 1 1 1 1 Myosin head (motor domain) UBA PF00627.26 CAM71150.1 - 7.2e-08 32.0 1.3 1.2e-05 24.9 0.1 3.2 3 0 0 3 3 3 1 UBA/TS-N domain AAA_22 PF13401.1 CAM71150.1 - 0.0025 17.9 0.0 0.013 15.6 0.0 2.3 1 0 0 1 1 1 1 AAA domain CUE PF02845.11 CAM71150.1 - 0.0026 17.2 0.2 12 5.4 0.0 3.8 3 0 0 3 3 3 1 CUE domain Myosin_N PF02736.14 CAM71150.1 - 0.0045 16.6 0.5 0.012 15.3 0.3 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Mg_chelatase PF01078.16 CAM71150.1 - 0.0046 16.1 0.0 0.027 13.6 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 CAM71150.1 - 0.13 12.2 3.6 0.19 11.7 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain Peptidase_C54 PF03416.14 CAM71152.1 - 3.4e-46 157.6 0.0 4.5e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Ribosomal_L2_C PF03947.13 CAM71153.1 - 5.4e-40 136.1 2.2 6.2e-40 136.0 0.8 1.6 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CAM71153.1 - 4.6e-13 48.9 0.0 1.5e-12 47.2 0.0 1.9 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain COPIIcoated_ERV PF07970.7 CAM71154.1 - 2.3e-37 128.7 0.3 3.1e-37 128.3 0.2 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CAM71154.1 - 7.5e-23 80.3 0.2 1.3e-22 79.5 0.1 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) ResIII PF04851.10 CAM71155.1 - 5.7e-13 49.0 0.0 1.2e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_3 PF13625.1 CAM71155.1 - 3.1e-12 46.3 0.3 6.9e-12 45.2 0.2 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C PF00271.26 CAM71155.1 - 3.9e-11 42.6 0.1 1.4e-10 40.8 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CAM71155.1 - 7.1e-08 31.5 0.1 4e-07 29.1 0.0 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain DEAD PF00270.24 CAM71155.1 - 0.032 13.7 0.0 0.62 9.5 0.0 2.8 1 1 0 1 1 1 0 DEAD/DEAH box helicase HECT PF00632.20 CAM71156.1 - 5.1e-44 150.7 0.2 1.2e-43 149.4 0.1 1.6 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.23 CAM71156.1 - 1.3e-28 99.5 0.0 1.6e-08 34.6 0.0 4.6 4 0 0 4 4 4 4 SPRY domain ZZ PF00569.12 CAM71156.1 - 0.0041 16.6 8.9 0.0093 15.4 6.1 1.6 1 0 0 1 1 1 1 Zinc finger, ZZ type PIN_4 PF13638.1 CAM71157.1 - 0.0087 16.1 0.0 0.03 14.4 0.0 2.0 1 1 0 1 1 1 1 PIN domain PG_binding_1 PF01471.13 CAM71159.1 - 0.068 13.1 1.1 0.31 11.0 0.0 2.6 4 0 0 4 4 4 0 Putative peptidoglycan binding domain cNMP_binding PF00027.24 CAM71160.1 - 8.3e-20 70.4 0.2 6.7e-08 32.2 0.0 4.0 3 1 0 3 3 3 3 Cyclic nucleotide-binding domain Gar1 PF04410.9 CAM71161.1 - 1.1e-23 83.3 0.0 1.4e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region LysM PF01476.15 CAM71163.1 - 2.1e-07 30.7 0.4 0.03 14.2 0.0 3.3 3 0 0 3 3 3 2 LysM domain HTH_23 PF13384.1 CAM71163.1 - 0.0025 17.4 0.0 5.5 6.7 0.0 3.5 3 0 0 3 3 3 2 Homeodomain-like domain Fringe PF02434.11 CAM71163.1 - 0.044 13.0 0.1 0.11 11.6 0.0 1.6 2 0 0 2 2 2 0 Fringe-like Death PF00531.17 CAM71163.1 - 0.05 13.3 0.0 11 5.8 0.0 3.3 3 0 0 3 3 3 0 Death domain HTH_Mga PF08280.6 CAM71163.1 - 0.23 11.2 0.1 8.3 6.2 0.0 2.9 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_AsnC-type PF13404.1 CAM71163.1 - 0.76 9.3 6.6 28 4.3 0.0 4.5 5 0 0 5 5 5 0 AsnC-type helix-turn-helix domain Herpes_UL52 PF03121.10 CAM71165.1 - 2.7e-15 55.8 0.9 1.5e-14 53.4 0.1 2.7 2 0 0 2 2 2 1 Herpesviridae UL52/UL70 DNA primase FOP_dimer PF09398.5 CAM71167.1 - 0.0046 16.9 0.0 0.0081 16.1 0.0 1.4 1 0 0 1 1 1 1 FOP N terminal dimerisation domain WD40 PF00400.27 CAM71168.1 - 1.5e-44 148.2 13.8 1.2e-10 40.8 0.2 7.6 8 0 0 8 8 8 7 WD domain, G-beta repeat PQQ_2 PF13360.1 CAM71168.1 - 0.0005 19.5 0.2 0.0048 16.3 0.1 2.2 2 0 0 2 2 2 1 PQQ-like domain PQQ PF01011.16 CAM71168.1 - 0.0025 17.2 0.0 2.2 7.9 0.0 2.9 2 0 0 2 2 2 2 PQQ enzyme repeat PQQ_3 PF13570.1 CAM71168.1 - 0.0028 17.8 0.1 6.3 7.2 0.0 4.3 4 1 0 4 4 4 1 PQQ-like domain DUF3312 PF11768.3 CAM71168.1 - 0.0077 14.5 0.1 0.3 9.2 0.0 2.4 1 1 0 2 2 2 1 Protein of unknown function (DUF3312) DUF4613 PF15390.1 CAM71168.1 - 0.012 13.7 0.1 0.016 13.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Nup160 PF11715.3 CAM71168.1 - 0.041 12.0 0.8 0.09 10.8 0.5 1.6 1 1 0 1 1 1 0 Nucleoporin Nup120/160 HEAT PF02985.17 CAM71169.1 - 1.1e-06 28.2 0.1 0.042 13.9 0.0 4.2 4 0 0 4 4 4 2 HEAT repeat UVR PF02151.14 CAM71169.1 - 0.0023 17.4 3.9 0.14 11.7 0.2 2.6 2 0 0 2 2 2 2 UvrB/uvrC motif HEAT_EZ PF13513.1 CAM71169.1 - 0.019 15.4 1.9 0.72 10.4 0.0 3.4 3 0 0 3 3 3 0 HEAT-like repeat HEAT_2 PF13646.1 CAM71169.1 - 0.055 13.7 2.5 2 8.7 0.0 3.1 2 1 0 2 2 2 0 HEAT repeats FAST_1 PF06743.10 CAM71171.1 - 0.039 13.6 0.4 1.6 8.4 0.0 2.7 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 Zip PF02535.17 CAM71172.1 - 7.8e-10 38.2 20.0 1.2e-07 31.0 0.4 3.1 2 1 1 3 3 3 3 ZIP Zinc transporter Sdh_cyt PF01127.17 CAM71172.1 - 4.9 6.9 7.5 0.22 11.3 0.2 2.4 3 1 0 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit CEP19 PF14933.1 CAM71175.1 - 1.1e-48 165.5 0.0 1.7e-48 164.8 0.0 1.3 1 0 0 1 1 1 1 CEP19-like protein Nop PF01798.13 CAM71176.1 - 1.7e-16 59.8 0.0 2.5e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 CAM71176.1 - 1.3e-14 53.7 0.1 2.4e-14 52.8 0.1 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain Dimerisation PF08100.6 CAM71176.1 - 0.066 13.0 0.3 0.36 10.6 0.1 2.2 2 0 0 2 2 2 0 Dimerisation domain Aminotran_1_2 PF00155.16 CAM71176.1 - 0.16 10.8 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Ank_2 PF12796.2 CAM71177.1 - 6.1e-19 68.1 2.1 6.5e-10 39.2 0.2 3.0 2 1 2 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.25 CAM71177.1 - 1.7e-09 36.9 7.0 2.6e-07 30.1 0.2 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 CAM71177.1 - 3.3e-07 30.6 2.0 0.0011 19.3 0.3 4.2 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CAM71177.1 - 4.8e-07 29.3 1.8 0.0034 17.4 0.1 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 CAM71177.1 - 2e-05 24.6 1.9 0.00072 19.7 0.2 3.3 2 1 1 3 3 3 1 Ankyrin repeats (many copies) DUF1762 PF08574.5 CAM71178.1 - 9.1e-05 22.8 2.6 0.00022 21.5 1.8 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1762) Tetraspannin PF00335.15 CAM71179.1 - 0.16 11.2 15.4 3.8 6.7 10.7 2.7 1 1 0 1 1 1 0 Tetraspanin family Tetraspannin PF00335.15 CAM71180.1 - 3.5e-10 39.5 14.2 5.9e-10 38.7 9.8 1.3 1 0 0 1 1 1 1 Tetraspanin family DUF4064 PF13273.1 CAM71180.1 - 0.49 10.5 7.9 0.6 10.2 4.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Claudin_2 PF13903.1 CAM71180.1 - 0.71 9.5 21.2 0.043 13.5 4.9 2.9 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction ABC2_membrane_4 PF12730.2 CAM71180.1 - 0.82 8.7 12.5 0.19 10.8 4.5 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein Cation_efflux PF01545.16 CAM71180.1 - 1.4 7.9 6.1 2.2 7.2 4.2 1.2 1 0 0 1 1 1 0 Cation efflux family Sugar_tr PF00083.19 CAM71183.1 - 7.5e-138 459.8 30.2 8.9e-138 459.6 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAM71183.1 - 1.6e-11 43.5 27.5 1.6e-11 43.5 19.1 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Peptidase_M14 PF00246.19 CAM71184.1 - 6.8e-22 78.3 0.0 1.3e-21 77.4 0.0 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF996 PF06195.8 CAM71185.1 - 2.3 8.2 12.4 1.2 9.1 1.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF996) zf-DHHC PF01529.15 CAM71187.1 - 3.3e-46 156.8 0.1 6.4e-46 155.9 0.0 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase A_deamin PF02137.13 CAM71188.1 - 1.5e-24 86.9 0.0 2.3e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain GST_N_3 PF13417.1 CAM71189.1 - 5.2e-34 116.3 0.2 4.1e-16 58.9 0.0 2.6 3 0 0 3 3 3 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CAM71189.1 - 7.2e-28 96.4 0.1 1.1e-13 50.9 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CAM71189.1 - 8.9e-16 57.8 0.4 2e-09 37.4 0.0 2.8 3 0 0 3 3 3 2 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CAM71189.1 - 8.7e-13 47.9 3.3 2e-05 24.3 0.2 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 CAM71189.1 - 4.1e-10 39.4 0.2 1.2e-07 31.6 0.1 2.5 2 0 0 2 2 2 2 Glutaredoxin GST_C PF00043.20 CAM71189.1 - 4.6e-07 29.7 0.1 0.0052 16.7 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CAM71189.1 - 9.6e-07 29.2 0.0 0.065 13.7 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain RRM_1 PF00076.17 CAM71191.1 - 2e-09 36.9 0.0 2.9e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM71191.1 - 1.5e-06 28.0 0.0 2.2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM71191.1 - 0.0008 19.2 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CAM71191.1 - 0.00094 19.0 0.0 0.0017 18.1 0.0 1.5 1 1 0 1 1 1 1 RNA binding motif WD40 PF00400.27 CAM71193.1 - 5.5e-26 89.4 14.0 0.00026 20.7 0.1 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Autophagy_N PF03986.8 CAM71194.1 - 3.2e-28 98.3 0.7 4.9e-28 97.7 0.5 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 CAM71194.1 - 4e-25 87.7 1.8 7.9e-25 86.8 1.3 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 CAM71194.1 - 4.2e-12 44.9 0.8 8.3e-12 43.9 0.6 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Glycos_transf_2 PF00535.21 CAM71195.1 - 0.018 14.7 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 ABC_tran PF00005.22 CAM71196.1 - 1.1e-44 152.0 0.1 9.5e-21 74.5 0.0 3.3 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 CAM71196.1 - 5.2e-19 69.2 0.0 0.00018 21.5 0.0 4.3 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 CAM71196.1 - 2.3e-11 43.3 2.1 0.0002 20.6 0.0 5.0 3 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CAM71196.1 - 7.5e-08 31.7 0.6 0.0091 15.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 CAM71196.1 - 3.5e-07 29.5 0.1 0.0091 15.1 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 CAM71196.1 - 5e-06 27.3 1.1 0.015 16.1 0.0 3.6 4 0 0 4 4 4 1 AAA domain SbcCD_C PF13558.1 CAM71196.1 - 4.6e-05 23.2 0.3 0.011 15.5 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 CAM71196.1 - 0.0002 20.8 1.1 2.4 7.4 0.0 3.9 4 0 0 4 4 4 1 AAA-like domain AAA_14 PF13173.1 CAM71196.1 - 0.00044 20.1 0.4 1.4 8.8 0.0 3.3 4 0 0 4 4 3 2 AAA domain AAA_15 PF13175.1 CAM71196.1 - 0.0007 18.7 0.5 21 4.0 0.0 4.7 5 1 0 5 5 5 0 AAA ATPase domain AAA_28 PF13521.1 CAM71196.1 - 0.00094 19.1 0.2 0.41 10.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CAM71196.1 - 0.00098 19.2 0.0 0.77 9.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.1 CAM71196.1 - 0.0013 18.8 0.0 2.2 8.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 CAM71196.1 - 0.0014 18.8 0.2 1.5 9.0 0.0 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 CAM71196.1 - 0.0015 18.9 0.5 2.5 8.6 0.0 3.5 3 0 0 3 3 3 1 Miro-like protein ABC_tran_2 PF12848.2 CAM71196.1 - 0.0018 18.1 3.2 0.0018 18.1 2.3 4.0 3 1 1 4 4 4 1 ABC transporter AAA_5 PF07728.9 CAM71196.1 - 0.0025 17.5 0.2 1.3 8.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CAM71196.1 - 0.0027 17.7 5.4 0.97 9.3 0.3 3.3 3 2 1 4 4 4 2 AAA ATPase domain MMR_HSR1 PF01926.18 CAM71196.1 - 0.0029 17.5 0.1 0.64 9.9 0.1 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.1 CAM71196.1 - 0.0058 16.5 0.2 1.2 8.9 0.0 3.1 3 0 0 3 3 2 1 AAA domain NACHT PF05729.7 CAM71196.1 - 0.044 13.4 0.0 5.1 6.7 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Mad3_BUB1_II PF08171.6 CAM71196.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Mad3/BUB1 homology region 2 AAA_18 PF13238.1 CAM71196.1 - 0.062 13.6 5.0 1.5 9.1 0.0 3.5 4 0 0 4 4 3 0 AAA domain Mg_chelatase PF01078.16 CAM71196.1 - 0.074 12.2 0.3 3.6 6.6 0.0 2.7 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.1 CAM71196.1 - 0.55 10.5 0.0 0.55 10.5 0.0 4.7 4 2 0 5 5 3 0 AAA domain WD40 PF00400.27 CAM71199.1 - 1.9e-15 56.0 1.5 4.9e-06 26.2 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat Abhydrolase_5 PF12695.2 CAM71202.1 - 2.2e-20 72.8 0.0 3.4e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CAM71202.1 - 2.9e-14 53.4 3.7 2e-12 47.4 2.5 2.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAM71202.1 - 4.1e-08 33.0 0.1 4.7e-06 26.3 0.3 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 CAM71202.1 - 2.6e-05 23.7 0.3 0.0032 16.9 0.2 2.2 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 CAM71202.1 - 0.0046 16.1 0.1 1.7 7.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family FSH1 PF03959.8 CAM71202.1 - 0.0058 16.0 0.0 0.0099 15.3 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 CAM71202.1 - 0.018 14.5 0.3 0.032 13.8 0.2 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.13 CAM71202.1 - 0.077 12.2 0.0 0.54 9.5 0.0 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family MutS_V PF00488.16 CAM71203.1 - 1.6e-81 273.1 0.0 2.7e-81 272.4 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CAM71203.1 - 3e-28 99.0 0.7 3e-28 99.0 0.5 1.9 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 CAM71203.1 - 1.3e-16 60.5 1.0 2.9e-16 59.4 0.7 1.7 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.1 CAM71203.1 - 0.028 13.9 0.0 0.31 10.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain MutS_II PF05188.12 CAM71203.1 - 0.084 12.9 1.3 0.26 11.3 0.1 2.3 2 0 0 2 2 2 0 MutS domain II Lipoprotein_7 PF01540.11 CAM71203.1 - 0.1 11.6 0.9 6.1 5.8 0.0 2.2 2 0 0 2 2 2 0 Adhesin lipoprotein Phage_term_sma PF07141.6 CAM71207.1 - 0.077 12.5 0.2 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 Putative bacteriophage terminase small subunit FAD_binding_7 PF03441.9 CAM71209.1 - 1.2e-97 326.4 1.1 2e-97 325.7 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 CAM71209.1 - 5.4e-32 110.8 0.0 1e-31 109.9 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase FAD-oxidase_C PF02913.14 CAM71211.1 - 0.059 12.6 0.0 0.059 12.6 0.0 1.7 2 0 0 2 2 2 0 FAD linked oxidases, C-terminal domain SET PF00856.23 CAM71213.1 - 5.3e-09 36.5 0.0 1.3e-08 35.3 0.0 1.7 1 0 0 1 1 1 1 SET domain ADH_N PF08240.7 CAM71214.1 - 9.4e-24 83.2 0.5 3e-23 81.6 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CAM71214.1 - 4.6e-19 68.2 0.0 7e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CAM71214.1 - 0.005 17.7 0.0 0.0083 17.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase LRR_4 PF12799.2 CAM71215.2 - 3.5e-22 77.5 0.0 0.0016 18.0 0.0 7.8 4 4 3 8 8 8 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM71215.2 - 4.4e-15 55.1 7.9 0.028 14.1 0.1 6.7 6 1 0 6 6 6 5 Leucine rich repeat LRR_6 PF13516.1 CAM71215.2 - 1.1e-05 24.9 1.9 0.44 10.7 0.0 5.5 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.28 CAM71215.2 - 0.0025 17.6 13.4 3.6 7.9 0.1 8.8 8 1 1 9 9 9 1 Leucine Rich Repeat LRR_7 PF13504.1 CAM71215.2 - 0.49 10.8 19.6 7.9 7.1 0.1 9.4 11 0 0 11 11 11 0 Leucine rich repeat NifU PF01106.12 CAM71216.1 - 4.7e-15 55.1 0.1 8.4e-15 54.2 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.6 CAM71216.1 - 2.6e-11 42.9 0.2 4.6e-09 35.7 0.1 2.4 2 0 0 2 2 2 2 Scaffold protein Nfu/NifU N terminal DUF2543 PF10820.3 CAM71216.1 - 0.0093 15.9 0.6 0.026 14.5 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2543) RtcB PF01139.12 CAM71218.1 - 3.7e-92 309.5 0.0 4.2e-92 309.3 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB FYVE PF01363.16 CAM71219.1 - 0.056 13.3 15.8 0.4 10.6 10.9 2.0 1 1 0 1 1 1 0 FYVE zinc finger DYW_deaminase PF14432.1 CAM71219.1 - 7.1 6.6 6.2 4.4 7.3 0.5 2.1 1 1 1 2 2 2 0 DYW family of nucleic acid deaminases WD40 PF00400.27 CAM71220.1 - 0.0041 16.9 1.2 7.4 6.6 0.0 4.1 4 1 0 4 4 4 3 WD domain, G-beta repeat SynMuv_product PF06047.6 CAM71221.1 - 6.3e-14 51.5 0.9 1.3e-13 50.6 0.6 1.4 1 0 0 1 1 1 1 Ras-induced vulval development antagonist BRE1 PF08647.6 CAM71223.1 - 5e-22 77.6 10.9 5e-22 77.6 7.5 10.9 3 2 6 9 9 9 1 BRE1 E3 ubiquitin ligase DUF3584 PF12128.3 CAM71223.1 - 0.0006 17.2 52.0 0.0006 17.2 36.0 3.7 1 1 0 3 3 3 1 Protein of unknown function (DUF3584) DUF4094 PF13334.1 CAM71223.1 - 0.0028 18.0 4.1 0.0028 18.0 2.9 8.3 6 4 3 9 9 9 1 Domain of unknown function (DUF4094) TMF_TATA_bd PF12325.3 CAM71223.1 - 0.015 15.0 2.2 0.015 15.0 1.5 10.8 2 2 8 11 11 11 0 TATA element modulatory factor 1 TATA binding AAA_13 PF13166.1 CAM71223.1 - 0.015 13.8 117.6 0.012 14.1 20.4 6.0 1 1 5 6 6 6 0 AAA domain Reo_sigmaC PF04582.7 CAM71223.1 - 0.089 11.9 45.7 0.043 12.9 1.9 7.1 1 1 4 7 7 7 0 Reovirus sigma C capsid protein IncA PF04156.9 CAM71223.1 - 0.98 8.9 138.1 0.026 14.1 4.9 8.6 2 1 5 7 7 7 0 IncA protein IGR PF09597.5 CAM71224.1 - 0.00065 19.5 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 IGR protein motif Apc3 PF12895.2 CAM71225.1 - 6.3e-05 23.0 0.1 0.11 12.6 0.0 3.9 3 2 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 IFT57 PF10498.4 CAM71227.1 - 1.1e-70 238.2 6.6 1.2e-70 238.0 4.6 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 AAA_13 PF13166.1 CAM71227.1 - 0.0017 16.9 3.6 0.0018 16.8 2.5 1.1 1 0 0 1 1 1 1 AAA domain IncA PF04156.9 CAM71227.1 - 0.0028 17.2 6.9 0.0057 16.2 4.8 1.6 1 0 0 1 1 1 1 IncA protein Reo_sigmaC PF04582.7 CAM71227.1 - 0.0035 16.5 1.0 0.0051 16.0 0.7 1.4 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Peptidase_M75 PF09375.5 CAM71227.1 - 0.0061 15.9 1.5 0.012 14.9 1.0 1.4 1 0 0 1 1 1 1 Imelysin Spc7 PF08317.6 CAM71227.1 - 0.024 13.3 7.1 0.033 12.8 4.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.14 CAM71227.1 - 0.026 12.3 6.7 0.033 12.0 4.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.7 CAM71227.1 - 0.039 13.7 10.1 0.11 12.2 2.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Apolipoprotein PF01442.13 CAM71227.1 - 0.077 12.4 11.0 0.15 11.5 7.6 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Laminin_II PF06009.7 CAM71227.1 - 0.083 12.6 10.0 1 9.1 0.2 2.3 1 1 1 2 2 2 0 Laminin Domain II CHDCT2 PF08074.6 CAM71227.1 - 0.11 12.2 1.9 0.25 11.0 0.8 1.8 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain TPR_MLP1_2 PF07926.7 CAM71227.1 - 0.16 11.7 10.4 0.33 10.6 6.9 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF745 PF05335.8 CAM71227.1 - 0.2 11.1 9.2 0.57 9.6 3.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) AKNA PF12443.3 CAM71227.1 - 0.36 10.8 8.4 1.4 9.0 0.7 2.6 2 1 1 3 3 2 0 AT-hook-containing transcription factor PilJ PF13675.1 CAM71227.1 - 0.6 10.4 7.1 0.58 10.4 0.4 2.9 1 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term WXG100 PF06013.7 CAM71227.1 - 0.94 9.5 8.3 7.9 6.5 4.2 2.8 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Fzo_mitofusin PF04799.8 CAM71227.1 - 0.97 8.7 8.0 1.2 8.5 4.9 1.6 1 1 0 1 1 1 0 fzo-like conserved region Atg14 PF10186.4 CAM71227.1 - 1.8 7.4 11.2 3.9 6.3 1.9 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF948 PF06103.6 CAM71227.1 - 3.9 7.3 7.5 15 5.5 2.2 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4200 PF13863.1 CAM71227.1 - 4.9 7.1 11.3 2.4 8.0 2.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF883 PF05957.8 CAM71227.1 - 5.8 7.3 7.0 5.6 7.4 0.6 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Adenylsucc_synt PF00709.16 CAM71228.1 - 0.18 10.4 0.1 0.25 9.9 0.1 1.1 1 0 0 1 1 1 0 Adenylosuccinate synthetase EF-hand_7 PF13499.1 CAM71229.1 - 5.4e-06 26.4 0.1 8.6e-06 25.7 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CAM71229.1 - 0.00049 19.7 0.0 0.001 18.7 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.27 CAM71229.1 - 0.0013 17.9 0.1 0.0041 16.3 0.0 1.9 1 1 1 2 2 2 1 EF hand DUF948 PF06103.6 CAM71230.1 - 8.1 6.3 6.4 3.1 7.7 0.3 2.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) He_PIG_assoc PF10632.4 CAM71232.1 - 0.023 13.9 0.0 0.098 12.0 0.0 2.0 1 0 0 1 1 1 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase WD40 PF00400.27 CAM71232.1 - 0.034 14.0 1.1 17 5.4 0.1 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat ERG4_ERG24 PF01222.12 CAM71233.1 - 9.9e-104 347.2 23.8 1.2e-103 346.9 16.5 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF3382 PF11862.3 CAM71233.1 - 0.083 12.8 0.1 2.2 8.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) DUF3984 PF13136.1 CAM71233.1 - 0.19 10.8 4.7 0.28 10.3 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) Corona_nucleoca PF00937.13 CAM71233.1 - 0.51 9.2 6.8 0.76 8.6 4.7 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein FtsX PF02687.16 CAM71233.1 - 1.2 8.9 5.8 0.38 10.5 0.1 2.7 3 0 0 3 3 3 0 FtsX-like permease family TPR_11 PF13414.1 CAM71235.1 - 2.1e-05 24.0 7.5 0.00016 21.2 0.7 2.8 1 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 CAM71235.1 - 0.0018 18.0 9.2 0.079 12.9 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 CAM71235.1 - 0.0032 17.5 4.1 0.0069 16.4 2.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 CAM71235.1 - 0.0035 16.8 7.9 0.41 10.3 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CAM71235.1 - 0.0098 16.2 0.4 0.032 14.5 0.3 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat SKI PF01202.17 CAM71235.1 - 0.07 12.9 1.3 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase TPR_16 PF13432.1 CAM71235.1 - 0.076 13.7 3.1 0.086 13.5 0.4 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2267 PF10025.4 CAM71235.1 - 0.11 12.5 0.8 0.24 11.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) PTR2 PF00854.16 CAM71236.1 - 2e-15 56.4 9.1 8.8e-14 51.0 0.0 3.7 3 1 0 3 3 3 2 POT family MFS_1 PF07690.11 CAM71236.1 - 8.7e-08 31.2 31.3 1e-06 27.7 8.4 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily Ribosomal_L6e PF01159.14 CAM71237.1 - 3.4e-33 114.1 0.4 1.1e-32 112.4 0.3 1.8 1 1 0 1 1 1 1 Ribosomal protein L6e KOW PF00467.24 CAM71237.1 - 0.0057 16.3 0.0 0.02 14.6 0.0 1.9 1 1 1 2 2 2 1 KOW motif OAD_gamma PF04277.8 CAM71237.1 - 2.3 8.6 10.5 0.79 10.1 2.7 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain WD40 PF00400.27 CAM71238.1 - 4.4e-15 54.8 6.7 6.7e-06 25.7 0.1 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat bact-PGI_C PF10432.4 CAM71239.1 - 0.0087 15.7 0.5 0.016 14.9 0.4 1.3 1 0 0 1 1 1 1 Bacterial phospho-glucose isomerase C-terminal region Vitelline_membr PF10542.4 CAM71239.1 - 0.031 13.8 1.9 0.11 12.1 1.3 1.9 1 0 0 1 1 1 0 Vitelline membrane cysteine-rich region AMNp_N PF10423.4 CAM71240.2 - 0.15 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial AMP nucleoside phosphorylase N-terminus DUF2040 PF09745.4 CAM71241.1 - 0.0029 17.4 0.4 0.0066 16.2 0.3 1.6 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 55 (DUF2040) NIF PF03031.13 CAM71242.1 - 2.6e-18 66.2 0.6 1.8e-16 60.2 0.1 2.3 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase Cyclin PF08613.6 CAM71243.1 - 3.1e-28 99.0 0.0 7.1e-28 97.8 0.0 1.6 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CAM71243.1 - 4.9e-05 22.8 0.0 7.7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Tubulin PF00091.20 CAM71245.1 - 2.8e-70 236.5 0.0 4.5e-70 235.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CAM71245.1 - 6.5e-48 161.9 0.1 9.7e-48 161.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CAM71245.1 - 5.7e-05 23.1 0.0 0.00013 21.9 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CAM71245.1 - 0.0078 15.6 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Oxidored_FMN PF00724.15 CAM71246.1 - 1.8e-71 240.9 0.0 3.3e-71 240.0 0.0 1.4 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.9 CAM71246.1 - 5.5e-16 59.0 0.2 9.2e-12 45.2 0.1 2.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CAM71246.1 - 1.4e-09 38.1 0.5 0.00013 22.2 0.3 3.3 3 1 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CAM71246.1 - 2.8e-09 36.8 0.2 1.4e-08 34.6 0.0 2.3 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CAM71246.1 - 3.4e-09 37.0 1.9 0.0064 16.5 0.1 3.6 3 1 2 5 5 4 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CAM71246.1 - 1.9e-07 30.3 0.3 0.0073 15.2 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 CAM71246.1 - 3.7e-07 28.9 3.7 1.5e-06 26.9 0.2 2.7 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.19 CAM71246.1 - 6.5e-07 28.5 0.5 6.5e-07 28.5 0.3 2.9 4 0 0 4 4 4 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 CAM71246.1 - 2e-06 27.1 0.9 3.2e-06 26.4 0.6 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CAM71246.1 - 1.3e-05 24.2 1.3 1.3e-05 24.2 0.9 2.1 2 1 0 2 2 2 1 FAD binding domain GIDA PF01134.17 CAM71246.1 - 1.5e-05 24.0 0.9 3.6e-05 22.8 0.5 1.7 1 1 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 CAM71246.1 - 2.2e-05 24.1 1.1 0.0084 15.7 0.0 2.6 3 0 0 3 3 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 CAM71246.1 - 3.9e-05 23.4 0.1 0.0063 16.2 0.0 2.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.1 CAM71246.1 - 0.00016 21.8 0.3 0.0046 17.1 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding Amino_oxidase PF01593.19 CAM71246.1 - 0.00017 20.8 0.4 0.032 13.3 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 CAM71246.1 - 0.00065 18.8 1.1 0.0042 16.1 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 CAM71246.1 - 0.00067 19.4 3.2 0.1 12.3 0.1 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding FMO-like PF00743.14 CAM71246.1 - 0.00078 17.7 0.1 3 5.9 0.0 3.1 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like UDPG_MGDP_dh_N PF03721.9 CAM71246.1 - 0.0053 16.1 0.0 0.049 13.0 0.0 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.12 CAM71246.1 - 0.0054 15.8 0.2 0.013 14.5 0.0 1.6 2 0 0 2 2 2 1 Thi4 family NAD_binding_2 PF03446.10 CAM71246.1 - 0.0069 16.2 0.1 0.68 9.7 0.0 3.0 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 CAM71246.1 - 0.023 15.1 0.2 6 7.3 0.0 2.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 CAM71246.1 - 0.034 13.2 0.1 1.9 7.5 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 CAM71246.1 - 0.046 13.2 0.7 0.13 11.8 0.2 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.1 CAM71246.1 - 0.071 13.1 2.5 4.1 7.3 0.3 3.0 3 0 0 3 3 3 0 NADH(P)-binding TrkA_N PF02254.13 CAM71246.1 - 0.09 12.7 0.1 14 5.6 0.0 3.0 3 0 0 3 3 3 0 TrkA-N domain ApbA PF02558.11 CAM71246.1 - 0.26 10.7 1.9 8.1 5.8 0.4 3.3 3 1 0 3 3 3 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 CAM71246.1 - 0.77 9.5 3.7 4.8 6.9 0.1 3.0 4 0 0 4 4 3 0 ThiF family TipAS PF07739.8 CAM71248.1 - 0.28 11.5 2.4 0.75 10.1 0.1 2.4 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain zf-Tim10_DDP PF02953.10 CAM71252.1 - 0.0082 15.4 3.0 0.29 10.4 2.1 2.4 1 1 0 1 1 1 1 Tim10/DDP family zinc finger DnaJ PF00226.26 CAM71253.1 - 2.4e-22 78.4 0.8 3.8e-22 77.8 0.5 1.3 1 0 0 1 1 1 1 DnaJ domain PSI_PsaJ PF01701.13 CAM71253.1 - 9.2 6.1 9.0 0.25 11.1 1.0 2.3 2 0 0 2 2 2 0 Photosystem I reaction centre subunit IX / PsaJ Ribosomal_S3_C PF00189.15 CAM71255.1 - 9.8e-16 57.7 1.0 9.8e-16 57.7 0.7 1.7 2 1 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 CAM71255.1 - 6.2e-09 35.2 0.2 1.5e-08 34.0 0.1 1.6 2 0 0 2 2 2 1 KH domain Iso_dh PF00180.15 CAM71256.1 - 0.24 10.3 0.2 0.34 9.7 0.2 1.2 1 0 0 1 1 1 0 Isocitrate/isopropylmalate dehydrogenase FIBP PF05427.6 CAM71258.1 - 1.6e-05 24.3 0.1 0.098 11.8 0.0 2.9 3 0 0 3 3 3 2 Acidic fibroblast growth factor binding (FIBP) WD40 PF00400.27 CAM71259.2 - 2.7e-09 36.5 4.5 0.00056 19.6 0.1 6.0 5 1 0 5 5 5 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CAM71259.2 - 0.14 10.9 0.0 0.53 8.9 0.0 1.9 2 0 0 2 2 2 0 Nup133 N terminal like Nckap1 PF09735.4 CAM71259.2 - 1.2 6.4 0.0 1.7 5.9 0.0 1.1 1 0 0 1 1 1 0 Membrane-associated apoptosis protein NAPRTase PF04095.11 CAM71260.1 - 1.6e-66 224.1 0.0 2e-66 223.7 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family SAM_2 PF07647.12 CAM71260.1 - 0.063 13.1 0.0 0.57 10.0 0.0 2.4 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) SR-25 PF10500.4 CAM71261.1 - 0.2 11.0 23.2 0.37 10.2 16.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Skp1 PF01466.14 CAM71262.1 - 6.2e-17 61.3 0.4 1.1e-16 60.5 0.3 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Rhodanese PF00581.15 CAM71263.1 - 2.4e-10 40.7 0.0 3.6e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain DAGAT PF03982.8 CAM71264.1 - 3.5e-19 68.6 0.1 5.4e-12 45.0 0.0 4.2 4 0 0 4 4 4 3 Diacylglycerol acyltransferase E1-E2_ATPase PF00122.15 CAM71265.1 - 4.5e-48 163.2 0.7 1.1e-47 162.0 0.5 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CAM71265.1 - 2.3e-37 128.2 5.4 2.3e-37 128.2 3.8 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CAM71265.1 - 1.6e-15 58.0 0.1 0.0003 21.2 0.0 3.5 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase HAD PF12710.2 CAM71265.1 - 5.6e-09 36.4 0.0 1.6e-08 34.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CAM71265.1 - 1.8e-06 27.3 0.0 4.1e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 CAM71265.1 - 4.6e-06 26.5 0.0 1.2e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CAM71265.1 - 7.8e-05 22.3 0.2 0.00013 21.6 0.2 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PSP1 PF04468.7 CAM71266.1 - 1e-09 38.2 0.9 3.7e-09 36.4 0.6 2.0 1 1 0 1 1 1 1 PSP1 C-terminal conserved region PPTA PF01239.17 CAM71267.1 - 8.4e-30 100.8 10.1 3.2e-08 32.5 0.2 5.6 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_MLP1_2 PF07926.7 CAM71269.1 - 0.007 16.1 1.4 0.007 16.1 1.0 2.0 3 0 0 3 3 3 1 TPR/MLP1/MLP2-like protein zf-C4H2 PF10146.4 CAM71269.1 - 1 9.3 3.9 0.79 9.6 0.2 2.3 2 1 0 3 3 3 0 Zinc finger-containing protein Abhydrolase_5 PF12695.2 CAM71270.1 - 3.7e-05 23.5 0.1 0.00025 20.8 0.0 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CAM71270.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family Voltage_CLC PF00654.15 CAM71271.2 - 1.9e-94 316.6 28.0 4.1e-93 312.2 17.3 2.2 2 0 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.23 CAM71271.2 - 3.8e-14 52.1 0.8 1.3e-07 31.3 0.1 2.5 2 0 0 2 2 2 2 CBS domain YEATS PF03366.11 CAM71273.1 - 4.6e-09 35.8 0.0 8.3e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 YEATS family Guanylate_kin PF00625.16 CAM71274.1 - 5.8e-49 166.0 0.0 7.2e-49 165.7 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.1 CAM71274.1 - 1.4e-07 31.8 0.1 3.1e-07 30.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CAM71274.1 - 4.1e-06 26.7 0.1 8.6e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CAM71274.1 - 1.6e-05 25.7 0.2 4.2e-05 24.3 0.0 1.7 1 1 1 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 CAM71274.1 - 0.00017 21.5 0.0 0.00027 20.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CAM71274.1 - 0.00025 21.1 0.1 0.0023 18.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 CAM71274.1 - 0.00066 18.9 0.0 0.00091 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 CAM71274.1 - 0.0025 17.8 0.1 0.008 16.1 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 CAM71274.1 - 0.012 16.1 0.0 0.023 15.1 0.0 1.4 1 1 0 1 1 1 0 Miro-like protein ADK PF00406.17 CAM71274.1 - 0.031 14.1 0.3 1.5 8.6 0.1 2.3 2 0 0 2 2 2 0 Adenylate kinase AAA_5 PF07728.9 CAM71274.1 - 0.046 13.4 0.0 0.15 11.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) MobB PF03205.9 CAM71274.1 - 0.054 13.2 0.0 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 CAM71274.1 - 0.08 12.8 0.0 0.27 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain Cytidylate_kin2 PF13189.1 CAM71274.1 - 0.089 12.6 0.2 0.13 12.1 0.1 1.6 1 1 0 1 1 1 0 Cytidylate kinase-like family ABC_tran PF00005.22 CAM71274.1 - 0.099 12.9 0.1 0.15 12.3 0.1 1.8 1 1 0 1 1 1 0 ABC transporter zf-CW PF07496.10 CAM71275.1 - 5.9e-18 64.3 12.5 8.8e-14 50.9 3.6 3.6 3 0 0 3 3 3 2 CW-type Zinc Finger DUF4503 PF14951.1 CAM71275.1 - 0.028 12.5 0.6 0.052 11.6 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) Yippee-Mis18 PF03226.9 CAM71276.1 - 0.0038 17.2 5.4 0.49 10.4 0.1 3.2 3 0 0 3 3 3 2 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SlyX PF04102.7 CAM71276.1 - 9.3 6.7 15.2 1.2 9.5 0.8 3.3 1 1 1 2 2 2 0 SlyX Selenoprotein_S PF06936.6 CAM71277.1 - 1.5 8.3 7.6 0.54 9.7 1.3 2.3 2 0 0 2 2 2 0 Selenoprotein S (SelS) Herpes_gE PF02480.11 CAM71279.1 - 0.0048 15.2 0.0 0.049 11.9 0.0 2.1 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 CAM71279.1 - 0.022 15.1 0.1 0.048 14.0 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain NPCBM_assoc PF10633.4 CAM71279.1 - 0.052 13.6 1.3 8.3 6.5 0.1 2.9 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase PUF PF00806.14 CAM71280.1 - 1.6e-50 165.7 6.3 4.5e-06 25.8 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Ax_dynein_light PF10211.4 CAM71283.1 - 4.1e-45 153.9 14.2 5.3e-45 153.5 9.8 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain SecM PF06558.7 CAM71283.1 - 0.011 15.3 0.9 0.1 12.2 0.3 2.2 2 0 0 2 2 2 0 Secretion monitor precursor protein (SecM) DUF2972 PF11186.3 CAM71283.1 - 0.015 15.2 1.1 0.019 14.8 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) TRAP-gamma PF07074.7 CAM71283.1 - 0.24 10.9 2.4 0.39 10.2 1.7 1.4 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Peptidase_S21 PF00716.12 CAM71283.1 - 0.46 9.7 7.3 0.081 12.2 2.7 1.5 2 0 0 2 2 2 0 Assemblin (Peptidase family S21) DUF972 PF06156.8 CAM71283.1 - 4.9 7.5 11.5 5.1 7.4 6.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) AAA PF00004.24 CAM71285.1 - 1.9e-14 53.9 0.0 8.2e-10 39.0 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CAM71285.1 - 4.1e-06 27.6 0.0 1.1e-05 26.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CAM71285.1 - 5.5e-06 26.1 0.0 1.7e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CAM71285.1 - 5e-05 23.3 3.6 9.4e-05 22.4 0.0 2.9 3 1 0 4 4 3 1 AAA ATPase domain AAA_19 PF13245.1 CAM71285.1 - 0.0002 21.0 0.0 0.00056 19.6 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 CAM71285.1 - 0.00042 20.4 0.0 0.0019 18.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CAM71285.1 - 0.00049 19.5 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 CAM71285.1 - 0.0011 18.5 0.0 0.0023 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CAM71285.1 - 0.0017 18.2 0.0 0.0038 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CAM71285.1 - 0.0028 17.9 0.0 0.012 15.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CAM71285.1 - 0.0031 16.5 0.0 0.0055 15.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 CAM71285.1 - 0.0042 16.5 0.0 0.008 15.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Arch_ATPase PF01637.13 CAM71285.1 - 0.0085 15.8 0.0 0.025 14.3 0.0 1.8 2 0 0 2 2 2 1 Archaeal ATPase Zeta_toxin PF06414.7 CAM71285.1 - 0.011 14.9 0.0 0.024 13.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 CAM71285.1 - 0.013 15.4 0.2 0.041 13.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.1 CAM71285.1 - 0.019 14.5 0.1 0.29 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 CAM71285.1 - 0.024 13.7 0.0 0.086 11.9 0.0 1.9 2 0 0 2 2 2 0 KaiC DUF815 PF05673.8 CAM71285.1 - 0.034 13.0 0.0 0.071 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IPT PF01745.11 CAM71285.1 - 0.039 13.1 0.0 0.065 12.3 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase Mg_chelatase PF01078.16 CAM71285.1 - 0.039 13.1 0.0 0.085 12.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 CAM71285.1 - 0.039 13.8 0.0 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 CAM71285.1 - 0.043 13.9 0.0 0.13 12.4 0.0 1.9 2 0 0 2 2 1 0 RNA helicase PhoH PF02562.11 CAM71285.1 - 0.071 12.3 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.17 CAM71285.1 - 0.099 11.4 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain PPR_2 PF13041.1 CAM71286.1 - 0.00011 22.0 0.3 0.00088 19.2 0.1 2.4 3 0 0 3 3 3 1 PPR repeat family PPR PF01535.15 CAM71286.1 - 0.00071 19.3 0.1 2 8.5 0.0 3.6 3 0 0 3 3 3 1 PPR repeat PPR_3 PF13812.1 CAM71286.1 - 0.0042 17.2 0.2 0.062 13.6 0.0 3.1 3 0 0 3 3 3 1 Pentatricopeptide repeat domain TPR_19 PF14559.1 CAM71286.1 - 0.015 15.6 0.0 0.097 13.0 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3613 PF12266.3 CAM71286.1 - 0.07 12.6 1.3 0.17 11.4 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3613) F-box PF00646.28 CAM71287.1 - 0.0064 16.1 0.3 0.018 14.7 0.2 1.7 1 0 0 1 1 1 1 F-box domain GcrA PF07750.6 CAM71287.1 - 0.069 13.3 2.1 0.11 12.6 0.1 2.1 2 0 0 2 2 2 0 GcrA cell cycle regulator UIM PF02809.15 CAM71287.1 - 0.075 12.6 0.1 0.2 11.3 0.1 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif F-box-like PF12937.2 CAM71287.1 - 3.4 7.4 7.4 1 9.1 1.6 2.6 3 0 0 3 3 3 0 F-box-like WD40 PF00400.27 CAM71288.2 - 2.7e-10 39.7 7.9 1.9e-06 27.5 0.0 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat SlyX PF04102.7 CAM71288.2 - 0.015 15.6 0.3 1.2 9.5 0.1 2.6 2 0 0 2 2 2 0 SlyX PQQ_3 PF13570.1 CAM71288.2 - 0.02 15.1 3.3 0.91 9.8 0.0 3.9 2 1 1 3 3 3 0 PQQ-like domain PQQ_2 PF13360.1 CAM71288.2 - 0.038 13.4 4.5 0.47 9.8 0.2 2.5 2 0 0 2 2 2 0 PQQ-like domain DUF3459 PF11941.3 CAM71288.2 - 0.059 13.4 0.5 4.5 7.4 0.0 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3459) Atg14 PF10186.4 CAM71288.2 - 0.09 11.7 0.2 0.17 10.7 0.1 1.5 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 WD40 PF00400.27 CAM71289.1 - 2.7e-11 42.8 12.6 9.9e-05 22.0 0.3 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat Atg14 PF10186.4 CAM71289.1 - 0.0028 16.6 2.8 0.0056 15.6 2.0 1.4 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 GAS2 PF02187.12 CAM71291.1 - 0.018 14.8 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Growth-Arrest-Specific Protein 2 Domain Thioredoxin PF00085.15 CAM71294.1 - 6.1e-10 38.7 0.1 9.8e-10 38.0 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CAM71294.1 - 0.0016 18.4 0.9 0.012 15.7 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like YfmQ PF10787.4 CAM71294.1 - 0.0062 15.8 0.2 0.0097 15.2 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised protein from bacillus cereus group Thioredoxin_2 PF13098.1 CAM71294.1 - 0.0097 16.0 1.2 0.027 14.6 0.8 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 CAM71294.1 - 0.029 14.0 0.1 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_7 PF13899.1 CAM71294.1 - 0.034 14.1 0.1 0.084 12.9 0.0 1.6 2 0 0 2 2 2 0 Thioredoxin-like Ribosomal_L29 PF00831.18 CAM71294.1 - 0.21 11.3 1.6 18 5.1 0.1 2.5 2 0 0 2 2 2 0 Ribosomal L29 protein MFS_1 PF07690.11 CAM71295.1 - 1.8e-16 59.8 45.9 8.4e-09 34.5 17.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.11 CAM71295.1 - 9.1e-06 24.6 23.5 3.9e-05 22.6 16.3 2.0 1 1 0 1 1 1 1 Nucleoside H+ symporter LacY_symp PF01306.14 CAM71295.1 - 9.3e-05 21.1 3.7 9.3e-05 21.1 2.6 2.2 2 0 0 2 2 2 2 LacY proton/sugar symporter MFS_1_like PF12832.2 CAM71295.1 - 0.00037 20.2 0.1 0.0021 17.8 0.1 2.3 1 0 0 1 1 1 1 MFS_1 like family DiS_P_DiS PF06750.8 CAM71295.1 - 0.043 13.6 0.2 0.18 11.6 0.1 2.1 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain ABC1 PF03109.11 CAM71296.1 - 5.3e-30 103.8 0.0 1.1e-29 102.8 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 CAM71296.1 - 0.02 14.2 0.0 0.05 12.9 0.0 1.7 1 0 0 1 1 1 0 RIO1 family WaaY PF06176.6 CAM71296.1 - 0.024 13.8 0.0 0.046 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.18 CAM71296.1 - 0.055 13.1 3.2 0.096 12.4 0.1 2.8 3 1 0 3 3 3 0 Phosphotransferase enzyme family Cwf_Cwc_15 PF04889.7 CAM71297.1 - 0.00032 20.5 8.7 0.0015 18.3 5.7 2.1 1 1 1 2 2 2 1 Cwf15/Cwc15 cell cycle control protein Chibby PF14645.1 CAM71297.1 - 0.066 13.1 2.1 1 9.2 0.0 2.3 1 1 0 2 2 2 0 Chibby family TFIIF_alpha PF05793.7 CAM71297.1 - 0.13 10.6 10.5 0.14 10.5 7.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RR_TM4-6 PF06459.7 CAM71297.1 - 1.6 8.5 6.7 1.6 8.5 4.1 1.3 1 1 0 1 1 1 0 Ryanodine Receptor TM 4-6 Dehydrin PF00257.14 CAM71297.1 - 3.5 7.9 9.2 10 6.4 6.2 2.1 1 1 0 1 1 1 0 Dehydrin Sporozoite_P67 PF05642.6 CAM71297.1 - 6.5 4.4 11.3 9 4.0 7.8 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3656 PF12392.3 CAM71299.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Collagenase Aminotran_1_2 PF00155.16 CAM71304.1 - 1e-50 172.7 0.0 1.2e-50 172.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 CAM71304.1 - 1.7e-06 26.5 0.2 2.6e-06 25.9 0.1 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 CAM71304.1 - 2.1e-05 23.7 0.1 3.1e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 CAM71304.1 - 2.4e-05 23.2 0.3 4.9e-05 22.2 0.2 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CAM71304.1 - 0.00034 19.8 0.0 0.00067 18.8 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase RNase_Zc3h12a PF11977.3 CAM71304.1 - 0.061 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain SNARE PF05739.14 CAM71305.1 - 6.9e-16 57.6 2.4 2.3e-15 56.0 1.7 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 CAM71305.1 - 5.9e-05 23.1 1.8 5.9e-05 23.1 1.3 2.3 2 0 0 2 2 2 1 Syntaxin Ubiquitin_3 PF14836.1 CAM71305.1 - 0.0098 15.5 0.4 0.023 14.3 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Syntaxin_2 PF14523.1 CAM71305.1 - 2.3 8.3 12.1 1.1 9.3 3.9 2.3 2 0 0 2 2 2 0 Syntaxin-like protein UPF0113 PF03657.8 CAM71306.1 - 0.0028 17.3 0.1 0.009 15.6 0.1 1.9 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0113) Clavanin PF05452.6 CAM71306.1 - 0.062 13.2 0.0 0.85 9.6 0.0 2.2 2 0 0 2 2 2 0 Clavanin Complex1_LYR_1 PF13232.1 CAM71307.1 - 2.1e-07 31.0 3.0 3.8e-07 30.2 2.1 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 CAM71307.1 - 7.6e-06 25.6 2.5 1.3e-05 24.9 1.7 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Acyl_transf_1 PF00698.16 CAM71307.1 - 0.095 12.0 0.1 0.1 11.8 0.1 1.1 1 0 0 1 1 1 0 Acyl transferase domain DUF1416 PF07210.7 CAM71307.1 - 0.12 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) GAPT PF11770.3 CAM71309.1 - 0.023 14.3 0.5 0.24 11.0 0.0 2.4 2 0 0 2 2 2 0 GRB2-binding adapter (GAPT) Pkinase PF00069.20 CAM71310.1 - 1.9e-65 220.5 0.0 3e-65 219.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM71310.1 - 1e-30 106.6 0.0 1.5e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM71310.1 - 1.9e-05 23.7 0.1 0.00026 20.0 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 CAM71310.1 - 3.2e-05 23.0 0.2 5.6e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 CAM71310.1 - 0.044 12.6 0.0 0.073 11.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DuffyBP_N PF12377.3 CAM71310.1 - 0.068 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Duffy binding protein N terminal MRP-L28 PF09812.4 CAM71311.1 - 0.00023 21.0 0.2 0.00039 20.2 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Hist_deacetyl PF00850.14 CAM71311.1 - 0.04 13.2 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 Histone deacetylase domain Imm31 PF15595.1 CAM71311.1 - 0.13 12.0 1.0 1.2 8.9 0.2 2.1 2 0 0 2 2 2 0 Immunity protein 31 Pkinase PF00069.20 CAM71312.1 - 1.5e-49 168.5 0.0 3.4e-27 95.2 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CAM71312.1 - 1.2e-29 103.1 0.0 1.4e-20 73.4 0.0 3.2 3 0 0 3 3 3 2 Protein tyrosine kinase FHA PF00498.21 CAM71312.1 - 4.5e-10 39.4 0.1 0.00066 19.7 0.0 2.7 2 0 0 2 2 2 2 FHA domain Kinase-like PF14531.1 CAM71312.1 - 3.7e-07 29.3 0.1 4.8e-05 22.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.17 CAM71312.1 - 0.0005 19.4 0.0 0.00093 18.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family WD40 PF00400.27 CAM71313.1 - 6.2e-18 63.9 23.8 0.00012 21.8 0.0 7.5 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 CAM71313.1 - 4.5e-05 21.7 7.1 0.023 12.8 0.3 3.3 1 1 2 3 3 3 2 Nucleoporin Nup120/160 IFP_35_N PF07334.8 CAM71313.1 - 0.064 13.2 10.8 2 8.4 0.7 3.4 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus zf-met PF12874.2 CAM71313.1 - 0.11 12.6 0.0 0.28 11.4 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type FUSC PF04632.7 CAM71313.1 - 0.18 10.1 16.0 0.27 9.6 11.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF972 PF06156.8 CAM71313.1 - 0.43 10.9 22.3 0.95 9.8 1.1 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF972) FlxA PF14282.1 CAM71313.1 - 0.69 9.8 15.9 0.14 12.1 1.2 2.8 1 1 1 2 2 2 0 FlxA-like protein OmpH PF03938.9 CAM71313.1 - 1.1 9.1 28.8 0.059 13.2 9.3 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) AAA_13 PF13166.1 CAM71313.1 - 2.5 6.4 14.4 3.5 5.9 10.0 1.1 1 0 0 1 1 1 0 AAA domain Tropomyosin_1 PF12718.2 CAM71313.1 - 9.4 6.0 29.6 0.11 12.3 11.1 2.3 1 1 1 2 2 2 0 Tropomyosin like Aa_trans PF01490.13 CAM71314.1 - 4.4e-52 176.9 18.9 5.3e-52 176.6 13.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CAM71314.1 - 9.7e-10 37.8 15.6 9.7e-10 37.8 10.8 2.8 2 1 0 2 2 2 2 Tryptophan/tyrosine permease family RRM_1 PF00076.17 CAM71316.1 - 2.7e-08 33.3 0.0 4e-05 23.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM71316.1 - 0.0035 17.2 0.0 0.028 14.3 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM71316.1 - 0.0036 17.1 0.0 0.031 14.1 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAM71317.1 - 2.7e-13 49.3 0.1 1.1e-09 37.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM71317.1 - 7e-10 38.7 0.2 1.1e-08 34.9 0.1 2.1 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM71317.1 - 2.1e-05 24.2 0.0 0.00035 20.3 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM71318.1 - 9e-10 38.3 0.1 4.6e-09 36.1 0.0 2.2 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAM71318.1 - 2.5e-09 36.6 0.0 7.3e-09 35.1 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM71318.1 - 5.3e-08 32.5 0.0 1.2e-07 31.4 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAM71319.1 - 1.4e-16 59.8 0.1 2.2e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM71319.1 - 1.5e-11 44.1 0.1 2.1e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM71319.1 - 0.007 16.2 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_7 PF13176.1 CAM71321.2 - 0.00039 20.0 1.8 7.1 6.7 0.0 4.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CAM71321.2 - 0.002 18.0 19.4 0.0093 15.8 1.4 5.8 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 CAM71321.2 - 0.17 11.5 12.0 18 5.1 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat ubiquitin PF00240.18 CAM71322.1 - 0.0035 16.7 0.4 2.6 7.4 0.0 2.9 3 1 0 3 3 3 2 Ubiquitin family C2 PF00168.25 CAM71322.1 - 0.1 12.4 0.4 0.51 10.2 0.0 2.2 2 0 0 2 2 2 0 C2 domain TPR_16 PF13432.1 CAM71323.1 - 0.0057 17.3 1.8 0.0057 17.3 1.3 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 CAM71323.1 - 0.023 15.3 0.1 0.023 15.3 0.1 6.1 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 CAM71323.1 - 0.21 12.0 8.8 0.39 11.2 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat PRA1 PF03208.14 CAM71325.1 - 6.1e-29 100.3 9.0 7.8e-29 100.0 6.2 1.1 1 0 0 1 1 1 1 PRA1 family protein zf-DHHC PF01529.15 CAM71325.1 - 1.4 8.3 5.7 2.2 7.6 4.0 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase GST_C PF00043.20 CAM71326.1 - 1.8e-13 50.2 0.0 3.1e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CAM71326.1 - 3.2e-09 36.8 0.0 7.3e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CAM71326.1 - 7.4e-08 32.7 0.0 2.3e-07 31.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CAM71326.1 - 1e-06 28.5 0.0 1.7e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CAM71326.1 - 0.0016 18.5 0.0 0.0035 17.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain KIAA1328 PF15369.1 CAM71327.1 - 0.076 12.8 0.9 2.3 7.9 0.0 2.6 2 1 0 3 3 3 0 Uncharacterised protein KIAA1328 TauE PF01925.14 CAM71328.1 - 2.4e-15 56.6 14.5 1.5e-08 34.3 4.6 2.4 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE DivIC PF04977.10 CAM71328.1 - 0.0066 15.9 0.1 0.015 14.7 0.1 1.5 1 0 0 1 1 1 1 Septum formation initiator DUF2681 PF10883.3 CAM71328.1 - 0.0068 16.5 0.4 0.062 13.5 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2681) DUF3611 PF12263.3 CAM71328.1 - 0.011 15.1 2.5 0.57 9.5 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3611) DUF4131 PF13567.1 CAM71328.1 - 0.055 12.8 0.4 1.3 8.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF2244 PF10003.4 CAM71328.1 - 0.089 12.1 0.1 0.089 12.1 0.1 2.7 3 0 0 3 3 3 0 Integral membrane protein (DUF2244) DUF3278 PF11683.3 CAM71328.1 - 0.089 12.7 1.2 14 5.7 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) RseC_MucC PF04246.7 CAM71328.1 - 0.11 12.0 7.5 2.2 7.8 0.4 3.0 2 1 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Ribul_P_3_epim PF00834.14 CAM71329.1 - 1.4e-59 200.5 0.0 1.7e-59 200.3 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.19 CAM71329.1 - 0.00068 19.0 0.2 0.0025 17.2 0.1 1.9 2 1 0 2 2 2 1 Orotidine 5'-phosphate decarboxylase / HUMPS family SIS_2 PF13580.1 CAM71331.1 - 0.074 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 SIS domain adh_short PF00106.20 CAM71332.1 - 1.3e-21 77.1 0.0 1.8e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CAM71332.1 - 2.5e-11 43.7 0.0 3.5e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CAM71332.1 - 1.5e-09 37.7 0.0 2.3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CAM71332.1 - 0.00021 21.3 0.1 0.0041 17.1 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 CAM71332.1 - 0.0026 17.5 0.0 0.0056 16.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 CAM71332.1 - 0.018 14.7 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 CAM71332.1 - 0.042 13.2 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 CAM71332.1 - 0.092 11.6 0.1 0.18 10.6 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Peptidase_M20 PF01546.23 CAM71334.1 - 5.3e-21 74.9 0.0 7.2e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CAM71334.1 - 1.4e-12 47.2 0.0 2.3e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain HEAT PF02985.17 CAM71335.1 - 1.6e-10 40.1 15.2 3.2 8.0 0.0 9.5 9 0 0 9 9 9 5 HEAT repeat HEAT_2 PF13646.1 CAM71335.1 - 1.1e-08 35.2 7.2 0.0019 18.4 0.2 6.5 5 2 1 6 6 6 2 HEAT repeats Vac14_Fab1_bd PF12755.2 CAM71335.1 - 0.013 15.8 5.1 0.77 10.1 0.1 4.5 5 1 0 5 5 5 0 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 CAM71335.1 - 0.43 10.4 8.8 13 5.6 0.4 4.7 5 0 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 CAM71335.1 - 9.9 6.7 10.5 16 6.1 0.1 5.7 7 0 0 7 7 7 0 HEAT-like repeat Pro_isomerase PF00160.16 CAM71336.1 - 7.6e-45 152.8 0.1 9.2e-45 152.6 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD YfkB PF08756.5 CAM71337.1 - 0.016 14.7 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 YfkB-like domain GTPase_Cys_C PF12631.2 CAM71337.1 - 0.053 13.9 1.1 6.4 7.2 0.1 2.3 2 0 0 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Tropomyosin_1 PF12718.2 CAM71337.1 - 0.36 10.6 5.3 1.6 8.5 0.1 2.1 2 0 0 2 2 2 0 Tropomyosin like CENP-F_leu_zip PF10473.4 CAM71337.1 - 0.68 9.7 3.7 0.83 9.5 0.1 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 C8 PF08742.6 CAM71338.1 - 0.11 12.8 1.0 0.21 11.8 0.7 1.5 1 0 0 1 1 1 0 C8 domain PIGA PF08288.7 CAM71340.1 - 2.2e-38 130.4 0.1 4.8e-38 129.4 0.0 1.6 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 CAM71340.1 - 7.1e-29 100.4 0.0 1.1e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 CAM71340.1 - 1.9e-17 63.5 0.2 6e-17 61.9 0.2 1.9 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 CAM71340.1 - 5.8e-15 55.7 0.0 1.2e-14 54.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 CAM71340.1 - 6.3e-13 49.0 0.0 1.1e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CAM71340.1 - 0.0042 17.3 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 ThiI PF02568.9 CAM71341.1 - 1.1e-46 158.8 0.2 1.7e-46 158.1 0.1 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Aminotran_5 PF00266.14 CAM71341.1 - 1.8e-28 99.3 0.2 1.1e-13 50.6 0.0 2.2 1 1 1 2 2 2 2 Aminotransferase class-V tRNA_Me_trans PF03054.11 CAM71341.1 - 8.6e-05 21.2 0.1 0.00017 20.2 0.0 1.5 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.8 CAM71341.1 - 0.0024 17.2 0.3 0.031 13.5 0.0 2.5 3 0 0 3 3 3 1 Queuosine biosynthesis protein QueC Arm PF00514.18 CAM71342.1 - 4.2e-07 29.5 2.6 0.46 10.3 0.0 5.1 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat TIMELESS PF04821.9 CAM71342.1 - 0.042 13.1 0.2 0.17 11.1 0.0 2.0 2 0 0 2 2 2 0 Timeless protein Nup84_Nup100 PF04121.8 CAM71343.1 - 0.00068 17.4 0.0 0.36 8.4 0.0 2.3 2 0 0 2 2 2 2 Nuclear pore protein 84 / 107 HEAT PF02985.17 CAM71344.1 - 0.082 13.0 0.8 12 6.2 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat DUF912 PF06024.7 CAM71345.1 - 0.013 15.4 0.1 0.019 15.0 0.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Pkinase PF00069.20 CAM71346.2 - 6e-48 163.2 0.0 9.1e-38 129.8 0.0 2.4 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAM71346.2 - 8.1e-28 97.1 0.1 2.4e-19 69.4 0.1 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase Ras PF00071.17 CAM71347.1 - 1.8e-50 170.5 0.0 2.1e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAM71347.1 - 1.5e-17 64.2 0.0 2.4e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAM71347.1 - 5.3e-16 58.3 0.0 6.3e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CAM71347.1 - 2.6e-06 26.7 0.0 3.7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CAM71347.1 - 8.3e-06 25.7 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CAM71347.1 - 0.00018 20.6 0.1 0.00091 18.4 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 CAM71347.1 - 0.00076 18.9 0.0 0.0048 16.3 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.1 CAM71347.1 - 0.0032 17.0 0.4 0.0063 16.1 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CAM71347.1 - 0.0044 17.0 1.3 0.033 14.1 0.4 2.5 2 1 0 2 2 2 1 AAA ATPase domain ATP_bind_1 PF03029.12 CAM71347.1 - 0.0065 16.0 0.3 0.028 13.9 0.0 1.9 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_29 PF13555.1 CAM71347.1 - 0.0068 15.9 1.3 0.021 14.3 0.9 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain DAP3 PF10236.4 CAM71347.1 - 0.012 14.5 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 SRPRB PF09439.5 CAM71347.1 - 0.023 13.9 0.1 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_10 PF12846.2 CAM71347.1 - 0.024 14.0 0.5 0.036 13.5 0.3 1.6 1 1 0 1 1 1 0 AAA-like domain MCM PF00493.18 CAM71347.1 - 0.024 13.4 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 MCM2/3/5 family ABC_tran PF00005.22 CAM71347.1 - 0.065 13.5 1.1 0.12 12.6 0.3 1.7 2 1 0 2 2 2 0 ABC transporter AAA_22 PF13401.1 CAM71347.1 - 0.081 13.0 0.1 0.24 11.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.8 CAM71347.1 - 0.085 11.7 0.2 0.17 10.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_5 PF07728.9 CAM71347.1 - 0.13 11.9 0.0 0.39 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) YTH PF04146.10 CAM71347.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.5 1 1 0 1 1 1 0 YT521-B-like domain G-alpha PF00503.15 CAM71347.1 - 0.17 10.5 0.4 1.9 7.0 0.2 2.2 1 1 1 2 2 2 0 G-protein alpha subunit ABC_membrane_2 PF06472.10 CAM71349.1 - 4.5e-67 226.1 0.3 6.4e-67 225.6 0.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 CAM71349.1 - 1.9e-18 67.0 0.0 3.5e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CAM71349.1 - 0.00079 19.4 0.0 0.0029 17.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 CAM71349.1 - 0.0046 16.2 0.1 0.21 10.7 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CAM71349.1 - 0.0068 15.9 0.2 0.017 14.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.3 CAM71349.1 - 0.013 12.8 0.6 0.019 12.3 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FtsK_SpoIIIE PF01580.13 CAM71349.1 - 0.023 14.1 0.0 0.047 13.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.1 CAM71349.1 - 0.035 14.2 0.7 1.2 9.3 0.1 3.2 4 0 0 4 4 4 0 AAA domain NACHT PF05729.7 CAM71349.1 - 0.04 13.5 0.1 0.31 10.6 0.0 2.4 3 0 0 3 3 3 0 NACHT domain Mg_chelatase PF01078.16 CAM71349.1 - 0.072 12.2 0.3 0.15 11.2 0.1 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.1 CAM71349.1 - 0.098 12.9 0.1 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.1 CAM71349.1 - 0.1 11.0 0.0 0.17 10.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain NOG1 PF06858.9 CAM71350.1 - 4.6e-28 96.8 0.0 1.6e-27 95.1 0.0 2.0 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.6 CAM71350.1 - 1.5e-24 85.4 6.8 2.2e-24 84.8 3.9 2.0 2 0 0 2 2 2 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.18 CAM71350.1 - 1.7e-16 60.2 0.0 3.9e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CAM71350.1 - 4.2e-09 35.8 0.0 9.6e-09 34.6 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 CAM71350.1 - 2.6e-05 24.6 0.0 8.2e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 CAM71350.1 - 0.0058 15.7 0.1 0.019 14.0 0.0 1.8 2 0 0 2 2 2 1 AIG1 family PduV-EutP PF10662.4 CAM71350.1 - 0.04 13.4 0.0 0.098 12.1 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FOP_dimer PF09398.5 CAM71353.1 - 1.5e-11 44.0 0.0 2.9e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 FOP N terminal dimerisation domain LisH PF08513.6 CAM71353.1 - 0.0028 17.3 0.1 0.006 16.3 0.1 1.6 1 0 0 1 1 1 1 LisH E2R135 PF11570.3 CAM71353.1 - 0.052 13.6 0.5 0.17 11.9 0.4 1.9 1 1 2 3 3 3 0 Coiled-coil receptor-binding R-domain of colicin E2 Snf7 PF03357.16 CAM71354.1 - 5.3e-18 64.9 8.2 5.3e-18 64.9 5.7 2.0 1 1 1 2 2 2 1 Snf7 Ist1 PF03398.9 CAM71354.1 - 0.017 14.5 1.2 0.083 12.2 0.8 2.0 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway HRDC PF00570.18 CAM71354.1 - 0.032 13.9 0.7 0.071 12.8 0.2 1.8 2 0 0 2 2 2 0 HRDC domain Baculo_E25 PF05274.6 CAM71354.1 - 0.061 12.9 0.1 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein E25 DUF1463 PF07316.6 CAM71354.1 - 0.16 11.5 0.7 0.73 9.4 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1463) CAF1C_H4-bd PF12265.3 CAM71355.1 - 8.8e-18 63.9 0.0 1.9e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 CAM71355.1 - 8.2e-09 35.0 7.0 0.0036 17.1 0.0 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF2457 PF10446.4 CAM71355.1 - 0.035 12.8 37.1 0.047 12.4 18.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) SDA1 PF05285.7 CAM71355.1 - 2.2 7.5 31.0 3.9 6.6 15.3 2.2 2 0 0 2 2 2 0 SDA1 SAPS PF04499.10 CAM71355.1 - 3.6 6.1 4.9 5.3 5.5 3.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Pho88 PF10032.4 CAM71356.1 - 6.6e-53 178.8 0.0 7.7e-53 178.5 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Pribosyltran_N PF13793.1 CAM71357.1 - 1.9e-39 134.0 0.2 7e-38 128.9 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 CAM71357.1 - 5.2e-22 78.4 0.7 3.1e-21 75.9 0.2 2.1 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 CAM71357.1 - 2.3e-13 49.9 0.1 4.8e-13 48.9 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CAM71357.1 - 0.0057 15.8 0.1 0.01 15.0 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF3298 PF11738.3 CAM71360.1 - 0.12 12.8 0.2 1.5 9.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3298) Pkinase PF00069.20 CAM71362.1 - 1.8e-60 204.3 0.0 3e-60 203.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM71362.1 - 5.1e-39 133.9 0.1 6.8e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 CAM71362.1 - 5.4e-09 36.1 0.1 1.9e-07 31.2 0.0 2.3 1 1 1 2 2 2 1 PH domain Kinase-like PF14531.1 CAM71362.1 - 1e-08 34.5 0.0 1.6e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH_9 PF15410.1 CAM71362.1 - 0.0015 18.6 0.1 0.067 13.3 0.0 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 CAM71362.1 - 0.049 13.8 1.1 0.35 11.1 0.1 2.4 1 1 0 2 2 2 0 Pleckstrin homology domain PH_3 PF14593.1 CAM71362.1 - 0.079 12.8 0.0 0.24 11.2 0.0 1.8 1 1 0 1 1 1 0 PH domain Skp1 PF01466.14 CAM71363.1 - 0.0032 17.4 0.1 0.0064 16.5 0.1 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain PEN-2 PF10251.4 CAM71364.1 - 4.6e-06 26.7 7.1 7.2e-06 26.1 4.9 1.5 1 1 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase 7tm_2 PF00002.19 CAM71364.1 - 0.0023 17.0 2.0 0.0028 16.7 1.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Peptidase_C2 PF00648.16 CAM71365.2 - 6.4e-27 94.3 0.0 1.2e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 CAM71365.2 - 5.8e-13 48.7 0.0 2.2e-06 27.3 0.0 3.4 3 0 0 3 3 3 2 Calpain large subunit, domain III MIT PF04212.13 CAM71365.2 - 6.2e-05 22.7 0.2 0.00015 21.6 0.1 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_11 PF13414.1 CAM71365.2 - 0.02 14.5 0.7 0.15 11.6 0.1 2.3 2 0 0 2 2 2 0 TPR repeat DNA_pol_B PF00136.16 CAM71367.1 - 1.7e-140 468.9 0.0 2.4e-140 468.4 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CAM71367.1 - 3.6e-75 252.8 0.0 6.3e-75 252.0 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 CAM71367.1 - 1.2e-21 76.4 8.9 3e-21 75.2 6.2 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 CAM71367.1 - 0.062 13.1 0.2 0.27 11.0 0.1 2.1 1 1 0 1 1 1 0 RNase_H superfamily zinc-ribbons_6 PF07191.7 CAM71367.1 - 0.52 10.1 7.1 2.7 7.8 0.3 2.9 3 0 0 3 3 3 0 zinc-ribbons zf-RING-like PF08746.6 CAM71367.1 - 3.9 7.5 8.9 9.5 6.3 1.2 3.0 2 0 0 2 2 2 0 RING-like domain SNF2_N PF00176.18 CAM71368.1 - 3.5e-79 265.7 0.3 2.5e-78 262.8 0.0 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.5 CAM71368.1 - 1.9e-21 76.0 0.6 5.2e-21 74.5 0.4 1.8 1 0 0 1 1 1 1 SLIDE Helicase_C PF00271.26 CAM71368.1 - 1.5e-16 60.0 0.0 2.1e-15 56.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAM71368.1 - 7.2e-06 25.9 0.2 0.00012 21.9 0.0 3.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CAM71368.1 - 0.0001 21.8 0.0 0.00031 20.2 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase HAND PF09110.6 CAM71368.1 - 0.0001 22.6 7.8 0.00036 20.8 5.4 2.0 1 0 0 1 1 1 1 HAND HDA2-3 PF11496.3 CAM71368.1 - 0.0016 17.3 0.0 0.0048 15.7 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Pkinase PF00069.20 CAM71369.1 - 7.5e-66 221.9 0.0 1.1e-65 221.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM71369.1 - 8.4e-40 136.4 0.0 1.3e-39 135.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.1 CAM71369.1 - 4.1e-12 46.0 1.3 1.5e-05 25.0 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CAM71369.1 - 9.1e-11 40.2 1.6 0.035 13.4 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 CAM71369.1 - 7.5e-10 38.2 2.4 0.00018 21.0 0.2 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 CAM71369.1 - 7.6e-09 34.7 1.2 0.057 13.3 0.1 5.1 3 1 1 4 4 4 2 EF-hand domain Kinase-like PF14531.1 CAM71369.1 - 8.7e-09 34.7 0.0 3.5e-08 32.7 0.0 1.8 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 CAM71369.1 - 2.2e-05 23.9 1.3 4.7e-05 22.8 0.9 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 CAM71369.1 - 0.0084 15.1 0.1 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CAM71369.1 - 0.079 12.6 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family TPR_12 PF13424.1 CAM71370.1 - 9.7e-19 67.0 16.7 3.8e-08 33.1 0.6 3.3 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 CAM71370.1 - 1.9e-12 46.6 6.2 5.9e-06 25.8 0.2 3.5 3 1 0 3 3 3 3 TPR repeat TPR_1 PF00515.23 CAM71370.1 - 4.3e-12 45.0 7.0 0.09 12.4 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 CAM71370.1 - 5.3e-09 35.3 10.1 0.49 10.4 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat Apc5 PF12862.2 CAM71370.1 - 1.2e-05 25.0 4.4 0.0047 16.7 0.1 2.8 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 5 TPR_8 PF13181.1 CAM71370.1 - 0.0015 18.1 2.7 28 4.8 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.4 CAM71370.1 - 0.023 14.6 0.3 0.071 13.0 0.2 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 CAM71370.1 - 0.06 13.1 6.3 59 3.8 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Apc3 PF12895.2 CAM71370.1 - 0.061 13.4 3.9 1.6 8.8 1.1 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.4 CAM71370.1 - 0.062 12.6 0.4 2.1 7.6 0.0 2.6 2 1 0 2 2 2 0 26S proteasome subunit RPN7 TPR_9 PF13371.1 CAM71370.1 - 0.15 11.9 2.1 3.1 7.7 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 CAM71370.1 - 0.89 9.5 5.1 2.9 7.9 0.0 3.7 5 0 0 5 5 4 0 Tetratricopeptide repeat MIF PF01187.13 CAM71372.1 - 1.2e-11 44.6 0.0 1.3e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.16 CAM71372.1 - 0.043 13.4 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 Tautomerase enzyme MIF PF01187.13 CAM71373.1 - 4.8e-09 36.3 0.0 5.2e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Topo_C_assoc PF14370.1 CAM71373.1 - 0.02 14.5 0.2 0.046 13.3 0.0 1.6 2 0 0 2 2 2 0 C-terminal topoisomerase domain OTT_1508_deam PF14441.1 CAM71374.1 - 1.6e-11 44.1 0.1 2e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 OTT_1508-like deaminase LisH PF08513.6 CAM71376.1 - 0.0011 18.6 0.8 0.0029 17.3 0.1 2.1 2 0 0 2 2 2 1 LisH V-ATPase_H_N PF03224.9 CAM71376.1 - 0.11 11.6 2.3 0.14 11.2 0.1 2.3 3 0 0 3 3 3 0 V-ATPase subunit H Vfa1 PF08432.5 CAM71376.1 - 4.6 7.2 11.8 9.7 6.1 8.2 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DOT1 PF08123.8 CAM71377.1 - 4.2e-15 55.6 0.1 6e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 CAM71377.1 - 6.1e-05 23.0 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAM71377.1 - 0.00075 20.0 0.0 0.0012 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAM71377.1 - 0.0016 18.0 0.0 0.0025 17.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CAM71377.1 - 0.039 12.9 0.1 0.12 11.4 0.0 1.7 1 1 1 2 2 2 0 Putative methyltransferase Methyltransf_12 PF08242.7 CAM71377.1 - 0.056 13.9 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DER1 PF04511.10 CAM71378.1 - 1.6e-32 112.5 12.1 2e-32 112.3 8.4 1.0 1 0 0 1 1 1 1 Der1-like family Pkinase PF00069.20 CAM71381.1 - 7.7e-54 182.5 0.0 1e-53 182.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM71381.1 - 1.5e-25 89.7 0.0 2.3e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CAM71381.1 - 1.5e-05 24.8 0.0 6.8e-05 22.7 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CAM71381.1 - 0.024 13.4 0.9 0.034 12.9 0.1 1.6 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 CAM71381.1 - 0.12 11.7 0.2 0.76 9.1 0.1 1.9 1 1 1 2 2 2 0 RIO1 family E1-E2_ATPase PF00122.15 CAM71383.1 - 5.2e-50 169.6 0.6 5.2e-50 169.6 0.4 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CAM71383.1 - 6.4e-38 131.3 2.2 6.4e-38 131.3 1.5 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 CAM71383.1 - 1.5e-36 124.3 3.7 3.9e-14 52.5 0.0 3.5 3 0 0 3 3 3 3 Heavy-metal-associated domain HAD PF12710.2 CAM71383.1 - 2.3e-15 57.2 0.0 5.6e-15 55.9 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CAM71383.1 - 1.1e-06 28.3 0.2 1.7e-05 24.5 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CoA_binding_2 PF13380.1 CAM71383.1 - 0.024 14.8 0.4 0.16 12.1 0.3 2.4 1 0 0 1 1 1 0 CoA binding domain His_Phos_1 PF00300.17 CAM71384.1 - 8.5e-25 87.6 0.1 8.5e-23 81.1 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Sporozoite_P67 PF05642.6 CAM71384.1 - 0.96 7.2 11.6 1.1 7.0 3.6 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen His_Phos_1 PF00300.17 CAM71385.1 - 2.5e-19 69.8 0.0 1e-18 67.9 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) zf-HIT PF04438.11 CAM71386.1 - 9.4e-07 28.3 12.0 1.8e-06 27.4 8.3 1.5 1 0 0 1 1 1 1 HIT zinc finger DUF2562 PF10814.3 CAM71386.1 - 2.1e-05 24.4 4.7 3.3e-05 23.8 3.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2562) zf-MYND PF01753.13 CAM71386.1 - 0.092 12.6 12.1 0.17 11.7 8.4 1.4 1 0 0 1 1 1 0 MYND finger zf-B_box PF00643.19 CAM71386.1 - 2.2 8.2 6.7 4.1 7.3 4.6 1.5 1 0 0 1 1 1 0 B-box zinc finger BRF1 PF07741.8 CAM71386.1 - 3 8.1 6.8 11 6.3 4.7 1.9 1 1 1 2 2 2 0 Brf1-like TBP-binding domain Ecl1 PF12855.2 CAM71386.1 - 8.7 5.7 10.3 9.8 5.5 5.0 2.7 2 1 0 2 2 2 0 Life-span regulatory factor Kinesin PF00225.18 CAM71388.1 - 4.8e-82 275.3 0.0 1e-81 274.2 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain NodZ PF05830.6 CAM71388.1 - 0.041 12.4 0.0 0.087 11.3 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) WD40 PF00400.27 CAM71389.1 - 8e-09 35.0 10.0 0.0093 15.8 0.1 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF3312 PF11768.3 CAM71389.1 - 0.0044 15.3 0.0 0.0073 14.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) Acid_PPase PF12689.2 CAM71390.1 - 8.3e-49 165.4 0.0 9.5e-49 165.2 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase Hydrolase PF00702.21 CAM71390.1 - 0.018 15.4 0.0 0.022 15.1 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD PF12710.2 CAM71390.1 - 0.047 13.8 0.0 0.066 13.3 0.0 1.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Tup_N PF08581.5 CAM71391.1 - 2.1 8.5 7.3 0.72 10.0 1.0 2.5 2 0 0 2 2 2 0 Tup N-terminal NUC173 PF08161.7 CAM71395.1 - 2.1e-10 40.2 0.2 9.9e-10 38.0 0.1 2.2 1 0 0 1 1 1 1 NUC173 domain Peptidase_M32 PF02074.10 CAM71396.1 - 9.7e-126 420.2 0.0 1.1e-125 420.1 0.0 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase Iso_dh PF00180.15 CAM71397.1 - 4.8e-106 354.6 0.0 6.4e-106 354.2 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PdxA PF04166.7 CAM71397.1 - 0.0061 15.8 0.1 0.0096 15.1 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthetic protein PdxA Kinesin PF00225.18 CAM71398.1 - 2.1e-102 342.2 0.0 3.5e-102 341.5 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain AAA_29 PF13555.1 CAM71398.1 - 0.00016 21.1 0.2 0.067 12.7 0.0 3.4 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CAM71398.1 - 0.00023 21.3 0.9 0.036 14.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 CAM71398.1 - 0.00071 20.0 0.0 0.0034 17.8 0.0 2.3 2 0 0 2 2 1 1 Miro-like protein Mg_chelatase PF01078.16 CAM71398.1 - 0.0014 17.8 0.0 0.22 10.6 0.0 3.3 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI DUF258 PF03193.11 CAM71398.1 - 0.0023 17.1 0.0 0.011 14.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 CAM71398.1 - 0.0029 17.6 3.4 0.011 15.7 0.0 3.3 4 0 0 4 4 3 1 AAA ATPase domain AAA_10 PF12846.2 CAM71398.1 - 0.0035 16.8 0.3 0.17 11.2 0.0 2.9 3 0 0 3 3 3 1 AAA-like domain FtsK_SpoIIIE PF01580.13 CAM71398.1 - 0.0036 16.7 2.7 7.8 5.9 0.0 3.6 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_28 PF13521.1 CAM71398.1 - 0.01 15.7 0.0 0.01 15.7 0.0 2.5 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.22 CAM71398.1 - 0.011 16.0 0.0 0.066 13.5 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.1 CAM71398.1 - 0.016 15.0 0.3 0.096 12.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 CAM71398.1 - 0.022 14.7 0.0 0.1 12.6 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 CAM71398.1 - 0.029 13.8 0.0 0.8 9.0 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein Ras PF00071.17 CAM71398.1 - 0.034 13.5 0.0 6 6.2 0.0 3.0 3 0 0 3 3 3 0 Ras family SmpA_OmlA PF04355.8 CAM71398.1 - 0.038 13.6 0.1 0.21 11.2 0.1 2.2 2 1 1 3 3 3 0 SmpA / OmlA family AAA_17 PF13207.1 CAM71398.1 - 0.044 14.5 0.0 0.52 11.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 CAM71398.1 - 0.055 13.6 0.4 5.1 7.3 0.0 3.1 3 0 0 3 3 3 0 RNA helicase MMR_HSR1 PF01926.18 CAM71398.1 - 0.059 13.3 0.0 2.6 8.0 0.0 3.0 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_24 PF13479.1 CAM71398.1 - 0.19 11.2 0.1 4.5 6.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Peptidase_M17 PF00883.16 CAM71399.1 - 1.4e-87 293.4 0.8 2.3e-87 292.7 0.0 1.7 2 0 0 2 2 2 1 Cytosol aminopeptidase family, catalytic domain 3HCDH_N PF02737.13 CAM71403.1 - 2.2e-43 147.9 0.0 3.7e-43 147.2 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 CAM71403.1 - 6.9e-21 74.4 0.2 6.4e-09 36.1 0.0 3.5 3 0 0 3 3 3 3 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DAO PF01266.19 CAM71403.1 - 0.00012 21.1 0.2 0.00042 19.3 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CAM71403.1 - 0.00066 19.6 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 CAM71403.1 - 0.0021 17.4 0.0 0.0039 16.6 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.1 CAM71403.1 - 0.0031 17.2 0.0 0.0062 16.3 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding F420_oxidored PF03807.12 CAM71403.1 - 0.0042 17.4 0.1 0.013 15.9 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 CAM71403.1 - 0.0052 16.7 0.1 0.011 15.7 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 CAM71403.1 - 0.0054 15.7 0.0 0.0083 15.1 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_Gly3P_dh_N PF01210.18 CAM71403.1 - 0.0082 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Methyltransf_18 PF12847.2 CAM71403.1 - 0.014 15.9 0.1 0.037 14.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_2 PF03446.10 CAM71403.1 - 0.015 15.1 0.2 0.042 13.6 0.1 1.8 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 CAM71403.1 - 0.022 14.8 0.0 0.052 13.6 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 CAM71403.1 - 0.037 12.9 0.0 0.064 12.1 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein DapB_N PF01113.15 CAM71403.1 - 0.038 13.9 0.0 0.094 12.6 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ldh_1_N PF00056.18 CAM71403.1 - 0.041 13.7 0.4 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain ThiF PF00899.16 CAM71403.1 - 0.055 13.2 1.7 0.079 12.7 0.3 1.9 2 1 0 2 2 2 0 ThiF family UDPG_MGDP_dh_N PF03721.9 CAM71403.1 - 0.066 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IlvN PF07991.7 CAM71403.1 - 0.073 12.4 0.1 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Gp_dh_N PF00044.19 CAM71403.1 - 0.11 12.3 0.0 0.24 11.3 0.0 1.6 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Peptidase_M16_C PF05193.16 CAM71404.1 - 5e-22 78.4 0.0 1.1e-21 77.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CAM71404.1 - 4.1e-06 26.6 0.0 1.1e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) SRPRB PF09439.5 CAM71405.1 - 1.3e-19 70.0 0.0 2.3e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 CAM71405.1 - 3e-06 26.8 0.1 1.6e-05 24.4 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CAM71405.1 - 0.00011 22.1 0.0 0.00024 21.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CAM71405.1 - 0.00062 20.2 0.0 0.0012 19.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 CAM71405.1 - 0.018 14.1 0.0 0.034 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 TPP_enzyme_N PF02776.13 CAM71405.1 - 0.019 14.4 0.3 0.019 14.4 0.2 1.9 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain AAA_22 PF13401.1 CAM71405.1 - 0.024 14.7 0.3 0.075 13.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 CAM71405.1 - 0.024 14.6 0.4 0.76 9.7 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain cobW PF02492.14 CAM71405.1 - 0.03 13.7 0.0 0.067 12.6 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 CAM71405.1 - 0.036 13.9 0.0 0.087 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CAM71405.1 - 0.042 13.2 0.0 0.12 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CAM71405.1 - 0.2 11.3 0.0 1 8.9 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase WD40 PF00400.27 CAM71406.1 - 4e-09 36.0 0.3 0.15 11.9 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat LIM PF00412.17 CAM71407.1 - 2.9e-06 27.2 0.3 5.2e-06 26.4 0.2 1.4 1 0 0 1 1 1 1 LIM domain DnaJ_CXXCXGXG PF00684.14 CAM71407.1 - 7.6 6.6 8.8 6.8 6.8 2.7 2.4 1 1 0 1 1 1 0 DnaJ central domain ThiF PF00899.16 CAM71408.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 ThiF family MoeZ_MoeB PF05237.8 CAM71408.1 - 0.096 12.2 0.0 0.28 10.7 0.0 1.8 1 0 0 1 1 1 0 MoeZ/MoeB domain zf-CCHC_4 PF14392.1 CAM71409.2 - 0.021 14.4 4.3 2.8 7.6 0.6 2.9 2 0 0 2 2 2 0 Zinc knuckle PyrI_C PF02748.10 CAM71409.2 - 0.089 12.2 0.1 9.4 5.7 0.0 2.4 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-CCHC PF00098.18 CAM71409.2 - 0.69 9.9 8.5 5.8 7.0 1.2 3.0 2 0 0 2 2 2 0 Zinc knuckle Filament PF00038.16 CAM71410.1 - 0.0023 17.4 7.6 0.0023 17.4 5.2 6.6 3 2 2 5 5 5 2 Intermediate filament protein IFT57 PF10498.4 CAM71410.1 - 0.0036 16.0 9.0 0.0036 16.0 6.2 5.5 2 2 2 5 5 5 1 Intra-flagellar transport protein 57 DnaJ PF00226.26 CAM71412.1 - 7.4e-11 41.6 0.0 2.1e-10 40.1 0.0 1.9 1 1 0 1 1 1 1 DnaJ domain Dor1 PF04124.7 CAM71412.1 - 0.017 13.6 0.0 0.021 13.2 0.0 1.3 1 0 0 1 1 1 0 Dor1-like family Mis12 PF05859.7 CAM71412.1 - 0.029 14.1 0.4 0.072 12.9 0.3 1.7 1 0 0 1 1 1 0 Mis12 protein Mnd1 PF03962.10 CAM71412.1 - 0.29 10.7 6.8 0.57 9.8 4.7 1.4 1 0 0 1 1 1 0 Mnd1 family MAT1 PF06391.8 CAM71412.1 - 0.32 10.5 4.2 0.52 9.8 2.9 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Latarcin PF10279.4 CAM71412.1 - 0.42 10.8 2.8 3.1 8.0 0.0 2.9 2 1 0 2 2 2 0 Latarcin precursor MCM PF00493.18 CAM71413.1 - 7.6e-111 370.0 0.0 1.2e-110 369.4 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CAM71413.1 - 3.3e-16 59.8 0.0 8.2e-16 58.5 0.0 1.7 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 CAM71413.1 - 1.6e-08 33.9 0.1 6e-07 28.8 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CAM71413.1 - 0.00025 20.5 0.0 0.002 17.6 0.0 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.6 CAM71413.1 - 0.0022 17.6 0.0 0.0054 16.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CAM71413.1 - 0.026 14.2 0.0 0.14 11.8 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 CAM71413.1 - 0.057 13.6 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Complex1_LYR PF05347.10 CAM71414.1 - 3.3e-06 26.7 0.5 6.6e-06 25.8 0.3 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CAM71414.1 - 0.021 14.9 1.0 0.043 14.0 0.7 1.6 1 0 0 1 1 1 0 Complex1_LYR-like ketoacyl-synt PF00109.21 CAM71415.1 - 3.7e-37 128.1 1.5 1.9e-36 125.8 1.0 2.0 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 CAM71415.1 - 4.4e-26 91.0 1.7 4.4e-26 91.0 1.1 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ETF PF01012.16 CAM71416.1 - 0.045 13.4 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 Electron transfer flavoprotein domain GTP_EFTU PF00009.22 CAM71417.1 - 5.7e-33 113.9 0.0 1.8e-32 112.3 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 CAM71417.1 - 9.2e-15 54.4 0.0 2.2e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 CAM71417.1 - 2.7e-10 40.2 1.1 5e-07 29.7 0.0 3.1 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CAM71417.1 - 1.2e-06 28.4 0.0 4.4e-06 26.6 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 CAM71417.1 - 0.001 19.0 0.3 0.001 19.0 0.2 2.8 2 1 0 2 2 2 1 AAA ATPase domain GTP_EFTU_D4 PF14578.1 CAM71417.1 - 0.0015 18.1 0.2 0.0041 16.7 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 CAM71417.1 - 0.0018 18.7 0.0 0.0079 16.6 0.0 2.2 1 0 0 1 1 1 1 Miro-like protein ATP_bind_1 PF03029.12 CAM71417.1 - 0.0043 16.6 0.0 0.015 14.8 0.0 1.8 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein Ras PF00071.17 CAM71417.1 - 0.025 13.9 0.0 0.12 11.7 0.0 2.0 1 1 0 1 1 1 0 Ras family Dynamin_N PF00350.18 CAM71417.1 - 0.042 13.6 14.1 0.082 12.7 3.8 4.3 2 1 0 2 2 2 0 Dynamin family MIP-T3 PF10243.4 CAM71417.1 - 0.049 12.1 32.0 0.079 11.4 22.2 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF258 PF03193.11 CAM71417.1 - 0.057 12.5 0.1 0.36 9.9 0.1 2.2 1 1 0 1 1 1 0 Protein of unknown function, DUF258 DUF4520 PF15016.1 CAM71418.1 - 1e-25 89.0 0.1 1.3e-23 82.3 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4520) Corona_NS3b PF03053.9 CAM71418.1 - 0.23 10.9 0.0 0.37 10.2 0.0 1.2 1 0 0 1 1 1 0 ORF3b coronavirus protein Carboxyl_trans PF01039.17 CAM71418.1 - 0.23 9.7 0.1 0.39 8.9 0.1 1.2 1 0 0 1 1 1 0 Carboxyl transferase domain UQ_con PF00179.21 CAM71420.1 - 2e-34 118.0 0.0 2.7e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CAM71420.1 - 0.0021 17.8 0.0 0.0037 17.0 0.0 1.5 1 1 0 1 1 1 1 Prokaryotic E2 family B Herpes_capsid PF06112.6 CAM71420.1 - 1.1 9.2 8.6 1.7 8.6 6.0 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Beach PF02138.13 CAM71421.2 - 3e-86 289.2 0.0 6.4e-86 288.1 0.0 1.6 2 0 0 2 2 2 1 Beige/BEACH domain Laminin_G_3 PF13385.1 CAM71421.2 - 9.7e-09 35.6 1.2 3.6e-08 33.7 0.7 2.2 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily GTP_EFTU PF00009.22 CAM71423.1 - 3e-21 75.6 0.0 7.8e-21 74.3 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CAM71423.1 - 1.6e-16 60.2 0.1 5.4e-16 58.5 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CAM71423.1 - 9.2e-05 22.4 0.9 0.00023 21.2 0.6 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 CAM71423.1 - 0.0057 16.1 0.1 0.88 9.0 0.0 3.4 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 CAM71423.1 - 0.0073 16.0 0.1 0.12 12.1 0.0 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 CAM71423.1 - 0.09 12.7 0.0 0.37 10.7 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase v110 PF01639.12 CAM71424.1 - 0.063 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Viral family 110 TFIIS_C PF01096.13 CAM71425.1 - 3e-15 55.5 8.3 6.1e-15 54.5 5.8 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) PWWP PF00855.12 CAM71425.1 - 3.9e-07 30.1 0.4 1.1e-06 28.7 0.0 1.9 2 0 0 2 2 2 1 PWWP domain Med26 PF08711.6 CAM71425.1 - 0.049 13.1 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 TFIIS helical bundle-like domain Baculo_LEF5_C PF11792.3 CAM71425.1 - 0.13 11.6 0.8 0.28 10.5 0.6 1.6 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain Sporozoite_P67 PF05642.6 CAM71425.1 - 2.6 5.8 4.4 3.3 5.4 3.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PWWP PF00855.12 CAM71426.1 - 5.9e-11 42.4 0.8 1e-10 41.6 0.0 1.8 2 0 0 2 2 1 1 PWWP domain Med26 PF08711.6 CAM71426.1 - 1e-09 37.7 0.0 1.7e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Lar_restr_allev PF14354.1 CAM71426.1 - 0.012 15.9 0.4 0.035 14.3 0.3 1.9 1 0 0 1 1 1 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.2 CAM71426.1 - 0.021 14.6 1.1 0.021 14.6 0.7 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_5 PF13719.1 CAM71426.1 - 0.047 13.2 2.5 0.31 10.6 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-DNA_Pol PF08996.5 CAM71426.1 - 0.082 12.2 0.4 0.17 11.2 0.3 1.5 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger TFIIS_C PF01096.13 CAM71426.1 - 0.094 12.3 2.5 0.3 10.7 1.7 1.9 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS) Zn-ribbon_8 PF09723.5 CAM71426.1 - 0.11 12.4 0.2 13 5.8 0.0 2.7 2 0 0 2 2 2 0 Zinc ribbon domain zf-ribbon_3 PF13248.1 CAM71426.1 - 0.13 11.5 0.7 1.8 7.8 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DUF4611 PF15387.1 CAM71426.1 - 0.15 12.2 6.3 0.26 11.4 2.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) zinc_ribbon_4 PF13717.1 CAM71426.1 - 0.16 11.6 2.8 0.86 9.3 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain DUF1675 PF07897.6 CAM71426.1 - 0.35 10.6 9.8 0.6 9.9 6.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) zinc_ribbon_2 PF13240.1 CAM71426.1 - 5.3 6.6 6.6 4.9 6.7 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain CHAP PF05257.11 CAM71427.1 - 3.1e-16 59.1 1.1 7.9e-16 57.8 0.3 2.0 2 0 0 2 2 2 1 CHAP domain Y_phosphatase3 PF13350.1 CAM71428.1 - 1.9e-33 116.0 0.7 2.4e-33 115.7 0.1 1.4 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 CAM71428.1 - 1.1e-10 41.4 0.5 3.1e-10 39.9 0.4 1.8 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 CAM71428.1 - 0.0057 16.0 0.0 0.008 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 CAM71428.1 - 0.14 11.7 0.6 0.52 9.8 0.4 2.0 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain CHAP PF05257.11 CAM71429.1 - 1.1e-12 47.7 0.0 2.7e-11 43.1 0.0 2.3 1 1 0 1 1 1 1 CHAP domain CHAP PF05257.11 CAM71430.1 - 1.7e-05 24.4 0.6 0.0034 17.0 0.0 3.0 3 0 0 3 3 3 2 CHAP domain DUF3760 PF12586.3 CAM71431.1 - 0.12 12.1 1.1 0.58 10.0 0.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3760) Lge1 PF11488.3 CAM71433.1 - 0.0019 18.3 0.9 1.6 8.9 0.0 2.9 2 0 0 2 2 2 2 Transcriptional regulatory protein LGE1 TAP42 PF04177.7 CAM71433.1 - 0.12 11.3 2.6 0.27 10.1 1.8 1.5 1 0 0 1 1 1 0 TAP42-like family DUF2499 PF10693.4 CAM71434.1 - 0.15 12.1 0.2 7.5 6.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2499) ABC_tran_2 PF12848.2 CAM71439.1 - 0.31 10.8 3.6 0.15 11.9 0.7 1.7 2 0 0 2 2 2 0 ABC transporter Med3 PF11593.3 CAM71441.1 - 0.3 10.2 36.3 31 3.6 25.1 2.4 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal ABC_tran PF00005.22 CAM71449.1 - 5.9e-10 39.5 0.0 0.00065 20.0 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SbcCD_C PF13558.1 CAM71449.1 - 0.00012 21.9 1.2 0.00059 19.7 0.3 2.6 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 CAM71449.1 - 0.088 12.9 0.0 0.61 10.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CAM71449.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 CAM71449.1 - 0.18 10.9 0.0 0.34 10.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Tyr-DNA_phospho PF06087.7 CAM71450.1 - 8.5e-66 222.3 0.0 7.2e-61 206.1 0.0 2.7 1 1 1 2 2 2 2 Tyrosyl-DNA phosphodiesterase HTH_IclR PF09339.5 CAM71452.2 - 1.1e-12 47.3 10.7 5.8 6.5 0.0 7.9 7 0 0 7 7 7 7 IclR helix-turn-helix domain DltD_C PF04914.7 CAM71452.2 - 0.16 11.8 0.0 1e+03 -0.5 0.0 5.3 7 0 0 7 7 7 0 DltD C-terminal region YqgF PF14639.1 CAM71454.1 - 2.7e-11 43.2 0.0 1.1e-10 41.2 0.0 2.0 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 SH2_2 PF14633.1 CAM71454.1 - 1.8e-10 40.2 0.1 3.2e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 SH2 domain HHH_7 PF14635.1 CAM71454.1 - 0.068 13.2 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif SH2 PF00017.19 CAM71454.1 - 0.082 12.7 0.5 3.3 7.5 0.0 2.8 2 0 0 2 2 2 0 SH2 domain Trypsin_2 PF13365.1 CAM71457.1 - 9e-08 32.1 0.0 1.3e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 CAM71457.1 - 0.013 15.1 0.6 0.018 14.6 0.4 1.5 1 1 0 1 1 1 0 Trypsin Ribosomal_S13_N PF08069.7 CAM71459.1 - 6.7e-25 86.7 2.0 6.7e-25 86.7 1.4 1.7 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 CAM71459.1 - 2.2e-21 75.3 0.3 3.4e-21 74.8 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 AAA_13 PF13166.1 CAM71461.1 - 0.032 12.7 0.1 5.2 5.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain Rab5-bind PF09311.6 CAM71461.1 - 0.036 13.9 0.7 0.036 13.9 0.5 2.0 2 0 0 2 2 2 0 Rabaptin-like protein DUF1664 PF07889.7 CAM71461.1 - 0.055 13.2 3.0 3.3 7.5 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) CCDC155 PF14662.1 CAM71461.1 - 0.066 12.8 5.4 0.083 12.4 0.4 2.5 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 HALZ PF02183.13 CAM71461.1 - 0.093 12.4 1.3 9.6 6.0 0.0 3.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper FAD-SLDH PF12318.3 CAM71461.1 - 0.097 12.3 8.9 0.097 12.3 0.3 2.5 1 1 1 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase Rootletin PF15035.1 CAM71461.1 - 0.31 10.9 10.0 2 8.3 0.6 2.7 3 0 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion Baculo_PEP_C PF04513.7 CAM71461.1 - 0.38 10.5 10.1 18 5.1 0.1 4.3 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lebercilin PF15619.1 CAM71461.1 - 1.4 8.2 6.5 5 6.4 0.2 2.5 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease SlyX PF04102.7 CAM71461.1 - 2 8.8 7.3 21 5.5 0.0 4.7 5 1 0 5 5 5 0 SlyX Toxin_57 PF15535.1 CAM71462.1 - 0.0036 17.3 5.9 2.2 8.3 0.1 4.1 1 1 3 4 4 4 2 Putative toxin 57 WW PF00397.21 CAM71462.1 - 1.9 8.3 12.8 23 4.9 0.1 4.6 4 0 0 4 4 4 0 WW domain Phage_integ_N PF09003.5 CAM71462.1 - 3.1 7.5 10.9 40 3.9 1.4 4.5 1 1 3 4 4 4 0 Bacteriophage lambda integrase, N-terminal domain DUF4585 PF15232.1 CAM71462.1 - 6.8 6.6 6.8 11 5.9 0.0 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4585) LSM PF01423.17 CAM71463.1 - 4.9e-13 48.4 0.1 7.1e-13 47.9 0.1 1.2 1 0 0 1 1 1 1 LSM domain Zip PF02535.17 CAM71464.1 - 2.6e-34 118.6 16.8 5.2e-34 117.6 11.7 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter Coatomer_WDAD PF04053.9 CAM71465.1 - 1.6e-136 455.6 0.0 2.6e-136 454.9 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 CAM71465.1 - 5.7e-42 140.1 4.2 8.7e-11 41.2 0.0 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat TPR_8 PF13181.1 CAM71465.1 - 0.04 13.7 0.1 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Clathrin PF00637.15 CAM71465.1 - 0.087 12.4 0.2 5.8 6.5 0.0 2.7 1 1 2 3 3 3 0 Region in Clathrin and VPS EF-hand_7 PF13499.1 CAM71466.1 - 5.5e-06 26.4 0.0 2.4e-05 24.4 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 CAM71466.1 - 7e-05 21.9 0.0 0.00016 20.8 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 CAM71466.1 - 0.00025 20.6 0.0 0.003 17.3 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 CAM71466.1 - 0.0023 17.0 0.0 0.024 13.9 0.0 2.6 2 0 0 2 2 2 1 EF hand Ribosomal_L44 PF00935.14 CAM71467.1 - 2.9e-31 107.3 8.9 4.4e-31 106.7 6.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 RPA_interact_C PF14768.1 CAM71467.1 - 0.11 12.8 0.4 0.61 10.5 0.3 1.9 1 1 0 1 1 1 0 Replication protein A interacting C-terminal ABC_tran PF00005.22 CAM71470.1 - 1.4e-18 67.5 0.0 2.2e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 CAM71470.1 - 0.011 15.2 0.0 0.032 13.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cys_Met_Meta_PP PF01053.15 CAM71470.1 - 0.015 13.5 0.0 0.03 12.6 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme AAA_16 PF13191.1 CAM71470.1 - 0.018 15.0 0.2 0.1 12.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.1 CAM71470.1 - 0.019 14.3 0.0 0.047 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 CAM71470.1 - 0.058 12.6 0.0 0.86 8.7 0.0 1.8 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 CAM71470.1 - 0.19 10.9 0.0 0.38 9.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 CAM71470.1 - 0.21 11.5 0.1 0.65 9.9 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase FA_desaturase PF00487.19 CAM71471.1 - 1.2e-25 90.4 31.3 1.2e-25 90.4 21.7 1.8 1 1 1 2 2 2 1 Fatty acid desaturase adh_short PF00106.20 CAM71472.1 - 5.2e-17 62.2 0.0 7.1e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CAM71472.1 - 2.5e-06 27.4 0.0 4.8e-06 26.5 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CAM71472.1 - 0.0013 18.3 0.1 0.0027 17.3 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CAM71472.1 - 0.0093 15.9 0.1 0.023 14.7 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 CAM71472.1 - 0.095 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_2 PF03446.10 CAM71472.1 - 0.099 12.4 0.0 0.24 11.2 0.0 1.6 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase LRR_4 PF12799.2 CAM71473.1 - 8.5e-15 53.9 0.6 0.0011 18.5 0.0 7.0 2 1 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM71473.1 - 5.9e-09 35.5 6.7 4.4e-05 23.1 0.0 5.3 5 1 1 6 6 6 2 Leucine rich repeat LRR_6 PF13516.1 CAM71473.1 - 4.9e-05 22.9 11.7 9.1 6.7 0.0 8.6 8 2 2 10 10 10 1 Leucine Rich repeat LRR_1 PF00560.28 CAM71473.1 - 0.00035 20.2 8.7 11 6.4 0.4 7.2 7 2 0 7 7 7 2 Leucine Rich Repeat LRR_7 PF13504.1 CAM71473.1 - 0.061 13.5 11.9 26 5.6 0.0 7.6 6 1 2 8 8 8 0 Leucine rich repeat LRR_5 PF13306.1 CAM71473.1 - 0.084 12.5 0.0 0.28 10.8 0.0 1.8 2 0 0 2 2 2 0 Leucine rich repeats (6 copies) Pkinase PF00069.20 CAM71474.1 - 2.8e-42 144.6 0.0 3.4e-42 144.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM71474.1 - 6.6e-25 87.6 0.0 7.7e-25 87.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM71474.1 - 4.7e-07 29.0 0.0 2.5e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CAM71474.1 - 0.043 13.5 0.0 7.7 6.1 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 CAM71474.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DnaJ PF00226.26 CAM71475.1 - 3.1e-13 49.2 0.0 6.1e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain CLPTM1 PF05602.7 CAM71476.1 - 4.8e-124 414.4 0.0 5.7e-124 414.1 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) peroxidase PF00141.18 CAM71478.1 - 3.6e-47 160.7 0.0 5.7e-47 160.1 0.0 1.3 1 1 0 1 1 1 1 Peroxidase zf-C2H2_6 PF13912.1 CAM71478.1 - 0.077 12.9 0.6 0.16 11.9 0.4 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger G6PD_C PF02781.11 CAM71479.1 - 1.9e-119 397.8 0.0 2.4e-119 397.5 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 CAM71479.1 - 4.1e-60 203.1 0.0 6.6e-60 202.4 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Lant_dehyd_N PF04737.8 CAM71481.1 - 0.023 14.7 0.1 0.083 12.9 0.0 2.0 2 0 0 2 2 2 0 Lantibiotic dehydratase, N terminus Lipoprotein_2 PF00921.12 CAM71482.1 - 0.14 12.1 0.2 0.31 11.0 0.1 1.5 1 0 0 1 1 1 0 Borrelia lipoprotein Herpes_UL52 PF03121.10 CAM71482.1 - 0.21 11.3 7.1 0.42 10.3 4.9 1.4 1 0 0 1 1 1 0 Herpesviridae UL52/UL70 DNA primase ADK PF00406.17 CAM71483.1 - 3.2e-51 173.1 0.0 3.8e-51 172.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 CAM71483.1 - 9.9e-14 50.7 0.0 2.3e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 CAM71483.1 - 1.9e-07 31.9 0.1 6.1e-07 30.2 0.0 1.7 1 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CAM71483.1 - 0.0065 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CAM71483.1 - 0.019 14.9 0.0 0.36 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 CAM71483.1 - 0.12 12.7 0.1 0.49 10.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain ADK PF00406.17 CAM71484.1 - 4.2e-28 98.1 0.0 5.5e-28 97.7 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 CAM71484.1 - 4.8e-11 42.1 0.0 9.5e-11 41.1 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 CAM71484.1 - 5.8e-07 30.3 0.0 7.4e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CAM71484.1 - 0.0026 17.6 0.1 0.0063 16.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CAM71484.1 - 0.017 15.0 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CAM71484.1 - 0.018 15.3 0.0 0.038 14.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain ALIX_LYPXL_bnd PF13949.1 CAM71484.1 - 0.11 11.4 0.0 1.8 7.4 0.0 2.3 2 1 0 2 2 2 0 ALIX V-shaped domain binding to HIV RuvB_N PF05496.7 CAM71484.1 - 0.14 11.2 0.0 0.31 10.0 0.0 1.7 1 1 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Ldh_1_C PF02866.13 CAM71485.2 - 5.2e-14 52.3 0.0 5.4e-13 49.0 0.0 2.1 1 1 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 CAM71485.2 - 4e-12 46.1 0.0 7e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 CAM71485.2 - 0.027 13.5 0.2 0.12 11.4 0.0 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ldh_1_N PF00056.18 CAM71486.1 - 1.5e-45 154.5 0.2 2e-45 154.1 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CAM71486.1 - 9.8e-42 142.6 0.0 1.4e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 CAM71486.1 - 0.00033 19.4 0.0 0.00051 18.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 CAM71486.1 - 0.001 19.3 0.1 0.0033 17.7 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 CAM71486.1 - 0.0024 17.8 0.0 0.0055 16.6 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 CAM71486.1 - 0.044 12.7 0.1 0.063 12.2 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 CAM71486.1 - 0.092 12.7 0.4 0.22 11.4 0.3 1.6 1 1 0 1 1 1 0 NADH(P)-binding Ldh_1_N PF00056.18 CAM71487.1 - 9.7e-37 125.9 0.0 1.4e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CAM71487.1 - 1e-33 116.5 0.0 1.6e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 CAM71487.1 - 0.00044 19.0 0.0 0.00067 18.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 CAM71487.1 - 0.0021 18.3 0.0 0.0049 17.1 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 CAM71487.1 - 0.05 12.6 0.0 0.31 10.0 0.0 2.1 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ldh_1_N PF00056.18 CAM71488.1 - 1.2e-41 141.8 0.0 1.6e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CAM71488.1 - 1.1e-37 129.4 0.0 1.5e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Semialdhyde_dh PF01118.19 CAM71488.1 - 0.13 12.6 0.1 0.46 10.7 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DUF3756 PF12581.3 CAM71488.1 - 0.25 11.0 1.5 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3756) Nop25 PF09805.4 CAM71489.1 - 4.8e-07 29.9 19.9 4.8e-07 29.9 13.8 3.4 2 1 1 3 3 3 1 Nucleolar protein 12 (25kDa) FmdE PF02663.9 CAM71489.1 - 0.14 12.0 0.5 8.9 6.2 0.2 2.7 2 1 0 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon SUZ PF12752.2 CAM71490.1 - 0.21 12.1 2.4 0.98 9.9 1.7 2.2 1 0 0 1 1 1 0 SUZ domain Methyltransf_26 PF13659.1 CAM71491.1 - 0.0086 16.1 2.7 0.046 13.7 1.9 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAM71491.1 - 0.1 13.1 0.6 0.4 11.2 0.1 2.0 1 1 0 2 2 2 0 Methyltransferase domain DUF1935 PF09149.5 CAM71492.1 - 1e-122 401.3 4.9 2.2e-32 111.1 0.1 4.1 4 0 0 4 4 4 4 Domain of unknown function (DUF1935) Glyco_hydro_98C PF08307.6 CAM71492.1 - 0.029 13.6 0.1 0.077 12.2 0.0 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 98 C-terminal domain DUF1935 PF09149.5 CAM71493.1 - 5.3e-116 379.7 0.0 4.5e-30 103.6 0.0 4.1 4 0 0 4 4 4 4 Domain of unknown function (DUF1935) CS PF04969.11 CAM71494.1 - 2.7e-09 37.4 0.0 4e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 CS domain EMP24_GP25L PF01105.19 CAM71495.1 - 3.5e-13 49.6 0.2 8.2e-13 48.4 0.1 1.7 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Baculo_PEP_C PF04513.7 CAM71496.1 - 0.016 15.0 18.5 0.39 10.5 1.4 5.3 3 1 4 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 CAM71496.1 - 0.2 10.7 10.0 0.11 11.6 0.7 3.2 1 1 2 3 3 3 0 Reovirus sigma C capsid protein RIIa PF02197.12 CAM71499.1 - 1.1e-06 27.9 0.5 1.9e-06 27.1 0.4 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Dpy-30 PF05186.8 CAM71499.1 - 0.00011 21.5 0.1 0.00026 20.4 0.0 1.7 1 1 0 1 1 1 1 Dpy-30 motif Sigma70_r2 PF04542.9 CAM71499.1 - 0.023 14.3 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-70 region 2 Pyr_redox_2 PF07992.9 CAM71500.1 - 7.5e-08 32.4 0.0 4.8e-06 26.5 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CAM71500.1 - 0.00081 18.3 1.1 0.004 16.1 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CAM71500.1 - 0.002 18.1 0.1 0.0064 16.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 CAM71500.1 - 0.0056 15.6 0.4 0.01 14.7 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 CAM71500.1 - 0.008 14.8 0.4 0.014 14.0 0.3 1.3 1 0 0 1 1 1 1 Tryptophan halogenase NAD_Gly3P_dh_N PF01210.18 CAM71500.1 - 0.033 13.9 0.1 0.059 13.0 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.9 CAM71500.1 - 0.047 12.1 1.0 0.57 8.5 0.4 2.3 2 0 0 2 2 2 0 HI0933-like protein DUF3115 PF11312.3 CAM71500.1 - 0.056 12.2 0.0 0.09 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3115) Thi4 PF01946.12 CAM71500.1 - 0.13 11.3 0.1 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Glyco_hydro_70 PF02324.11 CAM71500.1 - 0.13 10.0 0.0 0.18 9.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 NAD_binding_9 PF13454.1 CAM71500.1 - 0.14 11.8 3.0 0.35 10.6 0.1 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding TrkA_N PF02254.13 CAM71500.1 - 0.16 12.0 0.4 0.49 10.4 0.2 1.9 1 1 0 1 1 1 0 TrkA-N domain YajC PF02699.10 CAM71500.1 - 0.16 11.6 0.1 0.4 10.3 0.1 1.6 1 0 0 1 1 1 0 Preprotein translocase subunit Peptidase_C2 PF00648.16 CAM71501.1 - 0.00034 19.7 0.0 0.00077 18.5 0.0 1.5 2 0 0 2 2 2 1 Calpain family cysteine protease Mon1 PF03164.9 CAM71502.1 - 1.5e-23 83.0 0.0 2.9e-14 52.5 0.0 2.6 2 1 0 2 2 2 2 Trafficking protein Mon1 WD40 PF00400.27 CAM71503.1 - 9e-18 63.4 2.6 0.00039 20.2 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat PseudoU_synth_1 PF01416.15 CAM71504.1 - 7.3e-20 71.3 0.0 2.6e-10 40.6 0.0 3.4 2 1 0 2 2 2 2 tRNA pseudouridine synthase Synaphin PF05835.7 CAM71504.1 - 0.21 11.7 0.1 0.21 11.7 0.1 3.4 3 0 0 3 3 3 0 Synaphin protein START PF01852.14 CAM71505.1 - 0.005 16.1 0.1 0.0074 15.6 0.1 1.3 1 0 0 1 1 1 1 START domain DS PF01916.12 CAM71506.2 - 5.5e-13 48.7 0.0 9.8e-08 31.4 0.0 3.2 3 0 0 3 3 3 3 Deoxyhypusine synthase AAA PF00004.24 CAM71507.1 - 6.5e-09 36.0 0.0 1.2e-06 28.7 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CAM71507.1 - 6.2e-07 30.2 0.0 1.3e-06 29.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CAM71507.1 - 9.3e-07 28.6 0.0 2.1e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CAM71507.1 - 0.0001 22.3 0.0 0.00031 20.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 CAM71507.1 - 0.00074 19.4 0.0 0.002 18.0 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.1 CAM71507.1 - 0.0036 17.2 0.0 0.0074 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CAM71507.1 - 0.0061 16.2 0.0 0.0061 16.2 0.0 2.4 2 0 0 2 2 1 1 Part of AAA domain AAA_18 PF13238.1 CAM71507.1 - 0.0081 16.4 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CAM71507.1 - 0.016 15.4 0.0 0.051 13.7 0.0 1.9 2 0 0 2 2 2 0 RNA helicase DUF815 PF05673.8 CAM71507.1 - 0.019 13.9 0.0 0.03 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.1 CAM71507.1 - 0.022 14.9 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CAM71507.1 - 0.023 14.1 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 CAM71507.1 - 0.032 13.8 0.0 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Viral_helicase1 PF01443.13 CAM71507.1 - 0.033 13.7 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 CAM71507.1 - 0.035 13.6 0.0 0.24 10.9 0.0 2.3 1 1 1 2 2 2 0 AAA domain NACHT PF05729.7 CAM71507.1 - 0.065 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.7 CAM71507.1 - 0.13 11.3 0.0 0.28 10.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin KAP_NTPase PF07693.9 CAM71507.1 - 0.2 10.6 0.0 0.3 10.0 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_2 PF07724.9 CAM71507.1 - 0.22 11.4 0.0 0.36 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) eIF-5_eIF-2B PF01873.12 CAM71508.1 - 7.2e-32 109.6 0.1 1.2e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 CAM71508.1 - 2.1e-05 24.3 0.0 7e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon RNA_pol_Rpb1_5 PF04998.12 CAM71509.1 - 3.4e-80 269.2 0.0 9.6e-80 267.7 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 CAM71509.1 - 5.7e-62 208.5 0.0 1.1e-61 207.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.7 CAM71509.1 - 3.3e-55 187.7 0.0 4.9e-55 187.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.13 CAM71509.1 - 3.6e-32 111.2 0.0 8.6e-32 110.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 CAM71509.1 - 1.8e-31 108.0 0.0 4.4e-31 106.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 COG6 PF06419.6 CAM71510.1 - 1.9e-39 135.3 0.0 4.6e-36 124.1 0.0 3.4 3 1 0 3 3 3 3 Conserved oligomeric complex COG6 Filament PF00038.16 CAM71510.1 - 0.012 15.1 1.0 0.024 14.0 0.3 1.8 1 1 0 1 1 1 0 Intermediate filament protein DASH_Dad3 PF08656.5 CAM71510.1 - 0.041 13.5 0.1 2.6 7.8 0.0 2.7 2 0 0 2 2 2 0 DASH complex subunit Dad3 tRNA-synt_2d PF01409.15 CAM71510.1 - 0.14 11.2 0.5 0.28 10.3 0.3 1.4 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) Occludin_ELL PF07303.8 CAM71510.1 - 0.17 12.6 1.5 0.44 11.3 0.6 2.0 1 1 0 1 1 1 0 Occludin homology domain GAS PF13851.1 CAM71514.1 - 8.5e-06 25.1 3.7 2.8e-05 23.4 0.5 2.3 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding DUF4140 PF13600.1 CAM71514.1 - 0.0061 16.9 6.5 0.83 10.1 0.9 2.6 2 0 0 2 2 2 2 N-terminal domain of unknown function (DUF4140) HrpB7 PF09486.5 CAM71514.1 - 0.026 14.4 9.0 0.29 11.0 2.2 2.7 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Cortex-I_coil PF09304.5 CAM71514.1 - 0.096 12.7 4.4 0.18 11.8 1.1 2.4 2 0 0 2 2 2 0 Cortexillin I, coiled coil EzrA PF06160.7 CAM71514.1 - 0.12 10.5 4.7 0.054 11.6 0.8 1.9 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA COG2 PF06148.6 CAM71514.1 - 0.25 11.2 1.5 4.6 7.1 0.5 2.5 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Spectrin PF00435.16 CAM71514.1 - 0.34 11.2 7.3 0.98 9.7 0.8 2.8 3 0 0 3 3 3 0 Spectrin repeat IncA PF04156.9 CAM71514.1 - 0.42 10.1 6.3 5.1 6.6 0.8 2.3 2 0 0 2 2 2 0 IncA protein Med9 PF07544.8 CAM71514.1 - 0.84 9.4 4.4 2.6 7.8 0.7 2.8 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Troponin PF00992.15 CAM71514.1 - 1 9.3 7.9 0.082 12.9 0.8 2.2 2 0 0 2 2 2 0 Troponin CENP-Q PF13094.1 CAM71514.1 - 2.4 8.1 11.9 2.1 8.3 2.9 2.3 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Ribosomal_S25 PF03297.10 CAM71517.1 - 2.8e-43 146.2 4.0 3.2e-43 146.0 2.7 1.0 1 0 0 1 1 1 1 S25 ribosomal protein DUF3516 PF12029.3 CAM71517.1 - 0.089 11.5 0.3 0.094 11.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) WD40 PF00400.27 CAM71520.1 - 1.2e-47 158.0 20.2 4.7e-08 32.6 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat Ion_trans PF00520.26 CAM71521.1 - 1.6e-97 324.5 98.9 1.4e-31 109.3 12.7 4.6 4 0 0 4 4 4 4 Ion transport protein HEAT PF02985.17 CAM71522.1 - 6.3e-15 53.8 3.5 0.37 11.0 0.0 9.0 10 0 0 10 10 8 5 HEAT repeat HEAT_2 PF13646.1 CAM71522.1 - 4.9e-14 52.3 9.3 0.00029 21.0 0.1 6.2 5 1 3 8 8 7 6 HEAT repeats IBN_N PF03810.14 CAM71522.1 - 2.5e-10 40.1 0.0 1.9e-09 37.2 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_EZ PF13513.1 CAM71522.1 - 1.1e-09 38.4 14.4 0.00019 21.7 0.1 7.4 6 2 2 8 8 8 4 HEAT-like repeat Arm PF00514.18 CAM71522.1 - 3.7e-09 36.0 4.9 0.27 11.0 0.1 6.1 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 CAM71522.1 - 6.3e-06 24.7 0.6 0.03 12.6 0.0 3.1 3 0 0 3 3 3 2 Adaptin N terminal region MMS19_C PF12460.3 CAM71522.1 - 6.5e-05 21.8 0.1 0.027 13.2 0.0 3.4 3 2 2 5 5 5 1 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.2 CAM71522.1 - 0.0094 16.3 3.9 11 6.4 0.0 4.8 4 3 2 6 6 6 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 CAM71522.1 - 0.01 15.2 1.7 0.19 11.0 0.0 3.4 3 1 0 3 3 3 1 CLASP N terminal DUF2325 PF10087.4 CAM71522.1 - 0.045 13.5 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) U3snoRNP10 PF12397.3 CAM71522.1 - 0.12 12.2 8.4 7.6 6.5 0.0 5.5 5 2 2 7 7 7 0 U3 small nucleolar RNA-associated protein 10 Telomere_reg-2 PF10193.4 CAM71522.1 - 0.12 12.5 3.0 2 8.6 0.0 3.7 4 0 0 4 4 4 0 Telomere length regulation protein O-FucT PF10250.4 CAM71524.1 - 0.2 10.7 0.1 2.6 7.0 0.0 2.3 2 0 0 2 2 2 0 GDP-fucose protein O-fucosyltransferase DUF952 PF06108.7 CAM71526.1 - 0.024 14.4 0.0 0.059 13.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF952) Menin PF05053.8 CAM71526.1 - 2.6 6.0 6.8 4.7 5.2 4.7 1.4 1 0 0 1 1 1 0 Menin SNAP PF14938.1 CAM71527.1 - 5.4e-08 32.3 23.5 2.1e-06 27.0 7.5 3.1 2 1 1 3 3 3 2 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 CAM71527.1 - 0.0023 17.8 6.9 0.3 11.0 0.3 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 CAM71527.1 - 0.0075 16.1 11.1 0.059 13.3 0.3 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 CAM71527.1 - 0.011 16.3 3.0 10 7.0 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 CAM71527.1 - 0.018 14.7 0.1 0.99 9.3 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 CAM71527.1 - 0.026 14.1 4.9 2 8.1 0.0 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat LRR_4 PF12799.2 CAM71528.1 - 1.5e-14 53.1 15.6 0.00035 20.1 0.1 6.4 4 1 2 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM71528.1 - 0.00047 19.8 16.2 0.33 10.7 0.1 5.6 3 2 2 5 5 5 4 Leucine rich repeat LRR_6 PF13516.1 CAM71528.1 - 2.6 8.3 21.2 10 6.5 0.0 7.7 6 3 2 8 8 8 0 Leucine Rich repeat GTP_EFTU PF00009.22 CAM71530.1 - 9.2e-43 145.8 0.1 1.4e-42 145.2 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 CAM71530.1 - 7.3e-30 103.0 1.1 1.2e-29 102.3 0.7 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 CAM71530.1 - 1.6e-14 53.5 0.0 2.9e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.18 CAM71530.1 - 0.00024 21.0 0.1 0.00053 19.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 CAM71530.1 - 0.00043 19.7 0.0 0.0034 16.8 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Ras PF00071.17 CAM71530.1 - 0.0038 16.6 0.0 0.0069 15.7 0.0 1.4 1 0 0 1 1 1 1 Ras family GTP_EFTU_D2 PF03144.20 CAM71530.1 - 0.0058 16.7 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 FeoB_N PF02421.13 CAM71530.1 - 0.043 13.0 0.2 0.087 12.1 0.1 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B DUF677 PF05055.7 CAM71531.1 - 1.1e-05 24.3 2.5 1.2e-05 24.1 1.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF677) DUF4618 PF15397.1 CAM71531.1 - 0.0006 19.2 7.5 0.0006 19.2 5.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4618) Phage_Mu_Gam PF07352.7 CAM71531.1 - 0.0045 16.5 5.7 0.0045 16.5 3.9 1.9 1 1 1 2 2 2 1 Bacteriophage Mu Gam like protein Orthopox_A5L PF06193.6 CAM71531.1 - 0.0075 16.2 1.0 0.0089 15.9 0.7 1.2 1 0 0 1 1 1 1 Orthopoxvirus A5L protein-like Syntaxin PF00804.20 CAM71531.1 - 0.0081 16.2 4.6 0.0081 16.2 3.2 1.6 2 0 0 2 2 1 1 Syntaxin Nop16 PF09420.5 CAM71531.1 - 0.0092 16.0 2.6 0.01 15.9 1.8 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Rootletin PF15035.1 CAM71531.1 - 0.015 15.2 6.8 0.017 15.0 4.7 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion YscO PF07321.7 CAM71531.1 - 0.028 14.2 7.7 0.039 13.7 5.3 1.3 1 0 0 1 1 1 0 Type III secretion protein YscO DUF3450 PF11932.3 CAM71531.1 - 0.045 13.0 3.8 0.056 12.6 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DJ-1_PfpI PF01965.19 CAM71531.1 - 0.046 13.1 1.5 0.085 12.3 1.1 1.8 1 1 0 1 1 1 0 DJ-1/PfpI family IncA PF04156.9 CAM71531.1 - 0.065 12.8 10.7 0.04 13.5 6.2 1.4 1 1 0 1 1 1 0 IncA protein MethyTransf_Reg PF10119.4 CAM71531.1 - 0.092 13.2 0.5 0.39 11.2 0.0 1.9 1 1 1 2 2 2 0 Predicted methyltransferase regulatory domain Metal_resist PF13801.1 CAM71531.1 - 0.13 12.3 0.5 0.19 11.7 0.3 1.4 1 1 0 1 1 1 0 Heavy-metal resistance DUF2680 PF10925.3 CAM71531.1 - 0.16 11.8 0.4 0.16 11.8 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) Ax_dynein_light PF10211.4 CAM71531.1 - 0.18 11.6 10.7 0.23 11.2 7.4 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain NPV_P10 PF05531.7 CAM71531.1 - 0.18 12.0 0.7 0.32 11.2 0.5 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.7 CAM71531.1 - 0.18 12.1 3.7 5.7 7.3 0.3 2.4 1 1 1 2 2 2 0 SlyX FlxA PF14282.1 CAM71531.1 - 0.22 11.4 4.6 0.61 10.0 3.2 1.8 1 1 0 1 1 1 0 FlxA-like protein Rabaptin PF03528.10 CAM71531.1 - 0.29 11.0 12.1 0.7 9.8 8.4 1.6 1 1 0 1 1 1 0 Rabaptin Troponin PF00992.15 CAM71531.1 - 0.31 11.1 15.1 0.43 10.6 10.4 1.2 1 0 0 1 1 1 0 Troponin Ycf1 PF05758.7 CAM71531.1 - 0.41 8.2 6.0 0.45 8.1 4.2 1.0 1 0 0 1 1 1 0 Ycf1 DUF4094 PF13334.1 CAM71531.1 - 0.45 10.9 7.1 11 6.5 2.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) DUF4446 PF14584.1 CAM71531.1 - 0.51 10.1 7.4 0.31 10.8 3.7 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) HALZ PF02183.13 CAM71531.1 - 0.57 9.9 8.1 1.1 9.0 2.0 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper Syntaxin-6_N PF09177.6 CAM71531.1 - 0.57 10.6 5.1 0.65 10.4 3.0 1.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF342 PF03961.8 CAM71531.1 - 0.59 8.4 6.6 0.62 8.4 4.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DivIC PF04977.10 CAM71531.1 - 0.77 9.2 11.4 7.2 6.1 1.3 3.0 2 1 1 3 3 3 0 Septum formation initiator PRP1_N PF06424.7 CAM71531.1 - 0.79 10.0 5.3 0.92 9.8 3.6 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Tho2 PF11262.3 CAM71531.1 - 1.5 7.8 5.8 1.9 7.4 4.0 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Fib_alpha PF08702.5 CAM71531.1 - 1.5 8.9 6.6 8.1 6.5 0.5 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.14 CAM71531.1 - 1.6 6.4 4.6 1.5 6.5 3.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prefoldin_2 PF01920.15 CAM71531.1 - 1.6 8.5 12.5 0.6 9.9 6.7 1.7 1 1 0 1 1 1 0 Prefoldin subunit XkdW PF09636.5 CAM71531.1 - 2 8.3 5.6 4 7.3 3.9 1.5 1 1 0 1 1 1 0 XkdW protein ApoL PF05461.6 CAM71531.1 - 2 7.5 7.2 2.4 7.3 5.0 1.1 1 0 0 1 1 1 0 Apolipoprotein L APG6 PF04111.7 CAM71531.1 - 2.4 7.1 13.6 2.9 6.8 9.5 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Pox_A_type_inc PF04508.7 CAM71531.1 - 2.6 8.0 18.5 0.38 10.6 0.6 3.6 4 1 1 5 5 4 0 Viral A-type inclusion protein repeat DUF904 PF06005.7 CAM71531.1 - 2.9 8.2 14.2 1.6 9.0 8.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DUF883 PF05957.8 CAM71531.1 - 4 7.9 5.8 2.3 8.7 2.5 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) HSP70 PF00012.15 CAM71531.1 - 5 4.9 7.9 5.2 4.8 5.5 1.1 1 0 0 1 1 1 0 Hsp70 protein FlaC_arch PF05377.6 CAM71531.1 - 5.4 6.9 7.0 1.3e+02 2.5 4.8 2.3 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF1202 PF06717.6 CAM71533.1 - 0.13 11.5 4.9 0.2 10.8 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) NMO PF03060.10 CAM71534.1 - 7.8e-70 235.6 3.9 7.7e-69 232.3 2.7 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 CAM71534.1 - 5.8e-08 32.0 0.1 0.00027 19.9 0.7 2.4 1 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 CAM71534.1 - 8.7e-08 31.3 0.5 1.4e-07 30.6 0.3 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.16 CAM71534.1 - 7.7e-06 25.0 0.1 1.6e-05 24.0 0.0 1.5 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase ThiG PF05690.9 CAM71534.1 - 2.6e-05 23.4 1.0 4.1e-05 22.7 0.7 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 CAM71534.1 - 0.00058 18.8 0.3 0.001 18.0 0.2 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase Peripla_BP_6 PF13458.1 CAM71534.1 - 0.017 14.5 0.7 0.17 11.1 0.5 2.2 1 1 1 2 2 2 0 Periplasmic binding protein DUF1759 PF03564.10 CAM71535.2 - 0.045 13.5 2.3 0.13 12.0 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) COG5 PF10392.4 CAM71535.2 - 0.88 9.5 4.4 14 5.6 0.2 2.8 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF1664 PF07889.7 CAM71535.2 - 1.5 8.5 10.6 0.23 11.2 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Sec20 PF03908.8 CAM71535.2 - 1.7 8.3 3.0 0.91 9.2 0.2 2.0 2 0 0 2 2 2 0 Sec20 Sec20 PF03908.8 CAM71536.1 - 2.2 8.0 8.0 2.2 8.0 1.3 3.1 1 1 2 3 3 3 0 Sec20 AAA_13 PF13166.1 CAM71536.1 - 6.1 5.1 17.1 17 3.7 11.8 1.7 1 0 0 1 1 1 0 AAA domain LRR_4 PF12799.2 CAM71537.2 - 0.00037 20.0 1.5 6.1 6.5 0.0 4.5 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM71537.2 - 0.043 13.5 4.7 0.11 12.2 0.0 3.4 4 0 0 4 4 4 0 Leucine rich repeat JAB PF01398.16 CAM71538.1 - 1.3e-29 102.2 0.0 2.4e-29 101.3 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 CAM71538.1 - 4.2e-10 39.1 0.0 6.9e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain MitMem_reg PF13012.1 CAM71538.1 - 4.5e-08 33.1 0.6 8e-08 32.3 0.4 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function PSD3 PF07626.6 CAM71538.1 - 0.026 14.5 0.0 0.062 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1587) ABC_tran PF00005.22 CAM71540.1 - 3.9e-39 134.0 0.0 5e-22 78.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CAM71540.1 - 1.3e-32 113.3 21.8 3.1e-16 59.5 6.1 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.14 CAM71540.1 - 1e-08 34.6 1.1 0.00044 19.5 0.0 4.1 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CAM71540.1 - 5.4e-07 29.8 0.0 0.1 12.5 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA_25 PF13481.1 CAM71540.1 - 3.7e-05 23.2 0.0 0.018 14.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 CAM71540.1 - 4.3e-05 23.4 0.1 0.019 14.9 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CAM71540.1 - 0.00016 21.5 0.3 0.58 9.9 0.0 2.5 2 0 0 2 2 2 2 Dynamin family AAA_29 PF13555.1 CAM71540.1 - 0.00019 20.8 0.1 0.15 11.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 CAM71540.1 - 0.00042 19.5 0.1 0.092 11.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 CAM71540.1 - 0.0022 18.4 0.0 0.95 9.9 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 CAM71540.1 - 0.0023 17.9 5.7 0.4 10.6 0.1 3.6 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 CAM71540.1 - 0.0038 17.4 0.0 1.5 9.0 0.0 3.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CAM71540.1 - 0.016 15.3 0.2 0.79 9.8 0.0 3.1 3 1 0 3 3 2 0 AAA domain AIG1 PF04548.11 CAM71540.1 - 0.019 14.1 1.1 1 8.3 0.1 2.4 2 0 0 2 2 2 0 AIG1 family Arch_ATPase PF01637.13 CAM71540.1 - 0.046 13.4 0.1 0.28 10.8 0.0 2.2 3 0 0 3 3 3 0 Archaeal ATPase RNA_helicase PF00910.17 CAM71540.1 - 0.052 13.7 0.1 4.2 7.5 0.0 3.1 3 0 0 3 3 3 0 RNA helicase AAA_23 PF13476.1 CAM71540.1 - 0.11 12.8 0.4 20 5.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.10 CAM71540.1 - 0.23 10.0 0.1 0.9 8.1 0.0 1.8 2 0 0 2 2 2 0 Adenovirus IVa2 protein Repressor_Mnt PF11423.3 CAM71541.1 - 5e-06 25.7 18.5 0.15 11.4 1.0 4.5 3 0 0 3 3 3 3 Regulatory protein Mnt HHH_2 PF12826.2 CAM71541.1 - 4.7e-05 23.1 4.3 1.8 8.4 0.0 4.6 4 0 0 4 4 4 2 Helix-hairpin-helix motif Cep57_MT_bd PF06657.8 CAM71541.1 - 0.00018 21.3 4.9 0.00018 21.3 3.4 5.6 6 0 0 6 6 6 1 Centrosome microtubule-binding domain of Cep57 DUF2529 PF10740.4 CAM71541.1 - 0.003 17.0 11.0 1.8 7.9 0.1 4.5 4 0 0 4 4 4 3 Protein of unknown function (DUF2529) HHH_3 PF12836.2 CAM71541.1 - 0.0061 16.4 0.4 8.1 6.4 0.0 3.1 3 0 0 3 3 3 2 Helix-hairpin-helix motif Spc42p PF11544.3 CAM71541.1 - 0.039 13.8 2.0 15 5.5 0.4 3.5 2 0 0 2 2 2 0 Spindle pole body component Spc42p Mod_r PF07200.8 CAM71541.1 - 0.15 12.0 52.4 0.53 10.2 0.9 7.4 7 1 1 8 8 8 0 Modifier of rudimentary (Mod(r)) protein Tmemb_cc2 PF10267.4 CAM71541.1 - 0.66 8.4 26.0 3.5 6.1 3.0 5.9 2 1 4 6 6 6 0 Predicted transmembrane and coiled-coil 2 protein DUF641 PF04859.7 CAM71541.1 - 1.3 8.8 49.0 1.4 8.6 2.5 7.1 5 1 2 7 7 7 0 Plant protein of unknown function (DUF641) DUF874 PF05917.6 CAM71541.1 - 4.7 5.9 20.4 7.7 5.2 1.3 3.7 3 0 0 3 3 3 0 Helicobacter pylori protein of unknown function (DUF874) V_ATPase_I PF01496.14 CAM71541.1 - 6.7 4.4 20.6 10 3.7 0.1 4.1 3 1 1 4 4 4 0 V-type ATPase 116kDa subunit family ERM PF00769.14 CAM71542.2 - 1.9e-31 109.5 291.2 4.3e-05 23.1 25.0 9.2 1 1 10 11 11 11 11 Ezrin/radixin/moesin family Cast PF10174.4 CAM71542.2 - 3.5e-23 81.6 235.0 2.8e-09 35.6 48.4 7.5 1 1 6 7 7 7 7 RIM-binding protein of the cytomatrix active zone Phage_lysis PF03245.8 CAM71542.2 - 5.3e-17 61.9 256.3 0.25 11.3 7.6 15.3 3 2 12 15 15 15 15 Bacteriophage Rz lysis protein CENP-F_leu_zip PF10473.4 CAM71542.2 - 6e-12 45.6 258.8 0.11 12.3 13.1 12.5 2 2 15 17 17 17 16 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIVA PF05103.8 CAM71542.2 - 2.8e-10 40.3 210.5 0.48 10.4 4.3 15.4 2 1 13 15 15 15 13 DivIVA protein Mod_r PF07200.8 CAM71542.2 - 2.2e-08 34.1 193.8 0.15 12.0 13.7 13.8 2 1 12 14 14 14 12 Modifier of rudimentary (Mod(r)) protein GAS PF13851.1 CAM71542.2 - 4.6e-06 25.9 211.3 0.1 11.7 14.2 13.0 2 1 13 15 15 15 13 Growth-arrest specific micro-tubule binding ADIP PF11559.3 CAM71542.2 - 2.4e-05 24.2 236.5 0.2 11.5 9.4 14.0 2 1 14 17 17 17 13 Afadin- and alpha -actinin-Binding APG6 PF04111.7 CAM71542.2 - 0.00013 21.0 247.3 0.081 11.9 13.2 10.3 2 1 13 15 15 15 14 Autophagy protein Apg6 GST_C_2 PF13410.1 CAM71543.1 - 0.011 15.5 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain AsnC_trans_reg PF01037.16 CAM71543.1 - 0.079 12.6 0.0 0.11 12.1 0.0 1.3 1 1 0 1 1 1 0 AsnC family ParA PF10609.4 CAM71543.1 - 0.14 12.0 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 ParA/MinD ATPase like EF1_GNE PF00736.14 CAM71544.1 - 1.5e-29 101.5 1.8 2.5e-29 100.8 1.2 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain GST_C_3 PF14497.1 CAM71544.1 - 0.017 15.5 0.5 0.048 14.1 0.0 2.0 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain HTH_1 PF00126.22 CAM71544.1 - 0.11 12.2 0.1 7.3 6.4 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family DUF3275 PF11679.3 CAM71544.1 - 0.18 11.4 2.4 0.27 10.8 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Stm1_N PF09598.5 CAM71544.1 - 6.3 7.5 10.2 8.1 7.2 1.2 2.5 2 0 0 2 2 2 0 Stm1 Metallophos PF00149.23 CAM71545.1 - 1.1e-34 119.6 0.1 1.3e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CAM71545.1 - 0.026 14.3 0.0 0.037 13.8 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Ribosomal_L13 PF00572.13 CAM71546.1 - 4e-22 78.6 1.1 5.7e-22 78.1 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L13 DUF4455 PF14643.1 CAM71546.1 - 0.014 14.0 2.5 0.019 13.6 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) Nop14 PF04147.7 CAM71547.2 - 0.14 10.0 3.5 0.19 9.6 2.4 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_pol_Rpb6 PF01192.17 CAM71549.1 - 5e-19 67.7 0.5 8.8e-19 66.9 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 UQ_con PF00179.21 CAM71550.1 - 1e-19 70.3 0.0 1.6e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Zip PF02535.17 CAM71550.1 - 0.048 12.6 0.1 0.067 12.1 0.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RWD PF05773.17 CAM71550.1 - 0.085 12.7 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 RWD domain Mito_fiss_reg PF05308.6 CAM71552.1 - 0.11 11.8 10.2 0.36 10.1 7.1 1.9 1 1 0 1 1 1 0 Mitochondrial fission regulator SR-25 PF10500.4 CAM71552.1 - 2.6 7.4 11.7 6 6.2 8.1 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DNA_pol_viral_C PF00336.13 CAM71553.1 - 0.14 11.3 0.1 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Pkinase PF00069.20 CAM71554.1 - 1.4e-37 129.3 0.0 3.1e-28 98.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAM71554.1 - 5.9e-19 68.1 0.0 3.3e-14 52.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CAM71554.1 - 0.093 12.4 5.6 0.15 11.7 0.0 2.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 CAM71554.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 CAM71554.1 - 0.66 8.7 0.1 0.98 8.1 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Rhodanese PF00581.15 CAM71555.1 - 1.7e-09 37.9 0.0 0.0042 17.4 0.0 3.4 2 1 0 2 2 2 2 Rhodanese-like domain MgtE_N PF03448.12 CAM71555.1 - 0.11 12.8 0.2 1.7 9.0 0.0 2.5 2 0 0 2 2 2 0 MgtE intracellular N domain Amastin PF07344.6 CAM71557.1 - 6.3e-51 172.0 8.4 7.1e-51 171.8 5.9 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CAM71557.1 - 0.00075 19.2 9.2 0.00094 18.9 6.4 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction UNC-50 PF05216.8 CAM71557.1 - 0.49 9.5 7.5 0.67 9.1 5.2 1.1 1 0 0 1 1 1 0 UNC-50 family Lipase_3 PF01764.20 CAM71558.1 - 2.1e-07 30.6 0.0 4.8e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 CAM71558.1 - 6.4e-05 22.7 0.1 0.00019 21.1 0.1 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CAM71558.1 - 0.00012 22.0 0.4 0.00042 20.2 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 CAM71558.1 - 0.00045 19.6 0.2 0.0023 17.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Thioesterase PF00975.15 CAM71558.1 - 0.079 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Peptidase_M41 PF01434.13 CAM71559.1 - 2e-44 151.6 0.0 3.2e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CAM71559.1 - 2.9e-39 134.3 0.0 5e-39 133.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 CAM71559.1 - 0.0001 21.8 0.6 0.16 11.3 0.0 2.6 2 1 1 3 3 3 2 AAA domain AAA_19 PF13245.1 CAM71559.1 - 0.00014 21.4 0.3 0.0031 17.2 0.1 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_2 PF07724.9 CAM71559.1 - 0.0002 21.3 0.0 0.00043 20.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 CAM71559.1 - 0.00043 19.4 0.0 0.001 18.1 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CAM71559.1 - 0.00048 20.2 0.0 0.01 16.0 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CAM71559.1 - 0.00065 20.5 0.0 0.0022 18.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CAM71559.1 - 0.0009 19.2 0.3 0.1 12.5 0.1 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 CAM71559.1 - 0.0012 18.8 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 CAM71559.1 - 0.0022 16.8 0.0 0.0035 16.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 CAM71559.1 - 0.0065 15.8 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 CAM71559.1 - 0.0068 16.1 1.1 0.11 12.1 0.2 3.2 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 CAM71559.1 - 0.035 14.4 0.0 0.58 10.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.16 CAM71559.1 - 0.044 12.9 0.1 0.13 11.4 0.1 1.8 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 CAM71559.1 - 0.13 12.1 0.2 0.84 9.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain TPR_11 PF13414.1 CAM71560.1 - 6.6e-18 64.1 3.2 2.9e-06 26.8 0.0 3.6 2 1 1 3 3 3 3 TPR repeat SET PF00856.23 CAM71560.1 - 2e-14 54.2 0.0 7.2e-14 52.4 0.0 2.0 1 1 0 1 1 1 1 SET domain TPR_2 PF07719.12 CAM71560.1 - 4.2e-07 29.3 10.7 0.0004 20.0 0.2 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 CAM71560.1 - 5.1e-07 29.5 4.1 0.0056 16.6 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CAM71560.1 - 0.0055 17.2 4.2 0.12 13.1 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 CAM71560.1 - 0.0084 15.6 0.5 0.0084 15.6 0.3 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 CAM71560.1 - 0.039 13.7 2.0 0.11 12.3 0.0 2.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 CAM71560.1 - 0.086 12.6 1.9 1.2 9.1 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat UPRTase PF14681.1 CAM71561.1 - 2.2e-70 236.0 0.0 2.7e-70 235.8 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 CAM71561.1 - 8.7e-07 28.7 0.0 1.4e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain EF-hand_8 PF13833.1 CAM71562.1 - 1.7e-09 37.1 0.1 2.8e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 CAM71562.1 - 3e-09 36.8 0.0 5.3e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CAM71562.1 - 8.2e-07 27.8 0.0 0.00058 18.9 0.1 2.8 2 1 1 3 3 3 2 EF hand EF-hand_6 PF13405.1 CAM71562.1 - 1e-05 24.9 0.1 0.026 14.4 0.1 3.2 1 1 2 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 CAM71562.1 - 2.3e-05 23.5 1.6 6.2e-05 22.1 0.2 2.3 2 0 0 2 2 2 1 EF hand FG-GAP PF01839.18 CAM71562.1 - 0.042 13.5 0.4 0.17 11.6 0.3 2.1 1 0 0 1 1 1 0 FG-GAP repeat Ribosomal_60s PF00428.14 CAM71562.1 - 0.44 10.9 0.1 0.44 10.9 0.1 2.5 2 1 1 3 3 3 0 60s Acidic ribosomal protein N2227 PF07942.7 CAM71563.1 - 2e-93 312.3 0.0 2.5e-93 311.9 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 CAM71563.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Myosin_head PF00063.16 CAM71565.2 - 1.7e-195 651.0 0.0 1.2e-119 400.4 0.0 2.1 2 0 0 2 2 2 2 Myosin head (motor domain) Myosin_TH1 PF06017.8 CAM71565.2 - 1.2e-09 37.8 0.0 0.0025 17.1 0.0 3.7 3 1 0 3 3 3 2 Myosin tail FYVE PF01363.16 CAM71565.2 - 2.4e-05 24.1 7.3 5.8e-05 22.9 5.0 1.6 1 0 0 1 1 1 1 FYVE zinc finger AAA_22 PF13401.1 CAM71565.2 - 0.019 15.0 0.0 0.057 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 CAM71565.2 - 0.052 12.5 0.0 0.087 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 CAM71565.2 - 0.053 14.3 2.9 0.51 11.1 0.0 3.5 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.22 CAM71565.2 - 0.13 12.5 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_11 PF13086.1 CAM71565.2 - 1.8 8.0 4.6 22 4.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_membrane PF00664.18 CAM71566.1 - 1.2e-115 385.6 20.6 1.9e-62 211.2 6.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CAM71566.1 - 6.4e-67 224.0 0.0 4.2e-32 111.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CAM71566.1 - 6.9e-12 45.0 0.1 1.4e-05 24.4 0.0 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CAM71566.1 - 8.5e-07 29.2 0.0 0.3 11.0 0.0 3.7 3 1 0 3 3 3 2 AAA domain DUF258 PF03193.11 CAM71566.1 - 1.9e-06 27.1 0.0 0.035 13.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 ABC_ATPase PF09818.4 CAM71566.1 - 2.6e-05 23.0 0.0 0.025 13.1 0.0 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_22 PF13401.1 CAM71566.1 - 3.2e-05 24.0 1.4 0.13 12.3 0.0 4.0 2 2 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CAM71566.1 - 3.7e-05 24.5 0.0 0.026 15.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 CAM71566.1 - 6.9e-05 23.0 0.0 1.6 8.9 0.0 3.6 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 CAM71566.1 - 0.00022 20.6 0.5 0.86 9.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 CAM71566.1 - 0.00059 19.8 1.3 0.67 9.9 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 CAM71566.1 - 0.0021 17.8 0.0 0.051 13.2 0.0 2.7 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 CAM71566.1 - 0.0026 17.6 4.3 2.1 8.2 0.1 4.3 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.20 CAM71566.1 - 0.0028 17.2 0.2 0.99 8.8 0.0 2.8 3 0 0 3 3 2 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.8 CAM71566.1 - 0.015 14.1 0.1 0.81 8.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 CAM71566.1 - 0.017 15.2 0.3 4.8 7.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Miro PF08477.8 CAM71566.1 - 0.034 14.6 0.1 6.9 7.1 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein Zeta_toxin PF06414.7 CAM71566.1 - 0.049 12.7 0.0 4.9 6.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Viral_helicase1 PF01443.13 CAM71566.1 - 0.053 13.0 0.3 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 CAM71566.1 - 0.057 12.8 0.0 30 3.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.1 CAM71566.1 - 0.095 13.0 0.2 1.6 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF2852 PF11014.3 CAM71566.1 - 0.11 12.4 0.5 15 5.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) G-alpha PF00503.15 CAM71566.1 - 0.65 8.6 0.1 5 5.6 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit Amastin PF07344.6 CAM71567.1 - 1.1e-39 135.5 11.3 1.3e-39 135.2 7.8 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein MtrF PF09472.5 CAM71567.1 - 2.4 7.4 6.3 1.3 8.3 0.1 2.5 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Claudin_2 PF13903.1 CAM71567.1 - 3.2 7.4 16.4 3.9 7.1 10.4 1.9 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 CAM71568.1 - 8.3e-51 171.6 10.8 9.8e-51 171.4 7.5 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein NQR2_RnfD_RnfE PF03116.10 CAM71568.1 - 0.015 14.5 0.2 0.02 14.1 0.2 1.3 1 0 0 1 1 1 0 NQR2, RnfD, RnfE family Claudin_2 PF13903.1 CAM71568.1 - 0.18 11.4 18.6 0.016 14.9 7.8 2.3 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Peptidase_C6 PF00851.13 CAM71568.1 - 0.53 8.8 2.2 1 7.8 1.5 1.4 1 0 0 1 1 1 0 Helper component proteinase DUF4064 PF13273.1 CAM71568.1 - 0.62 10.2 6.5 6.2 6.9 0.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) SUR7 PF06687.7 CAM71568.1 - 7.1 6.1 25.2 1.3 8.5 7.2 3.0 1 1 1 3 3 3 0 SUR7/PalI family Amastin PF07344.6 CAM71570.1 - 1e-54 184.3 17.3 1.2e-54 184.1 12.0 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Acyltransferase PF01553.16 CAM71572.2 - 6.3e-18 64.4 0.0 1.5e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase DUF2363 PF10155.4 CAM71573.2 - 0.2 11.5 0.1 0.31 10.9 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2363) SBDS_C PF09377.5 CAM71574.1 - 4.2e-31 107.2 0.0 7.6e-31 106.4 0.0 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 CAM71574.1 - 1.3e-24 85.7 0.4 2.4e-24 84.9 0.3 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DUF1042 PF06294.6 CAM71575.1 - 1e-32 112.9 0.0 1.8e-32 112.1 0.0 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1042) CAMSAP_CH PF11971.3 CAM71575.1 - 1.3e-23 82.4 0.0 2.2e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain CH PF00307.26 CAM71575.1 - 3e-05 23.9 0.0 5.7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Seryl_tRNA_N PF02403.17 CAM71575.1 - 0.051 13.5 0.5 0.26 11.3 0.1 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 CAM71575.1 - 0.064 12.8 0.2 0.11 12.0 0.2 1.3 1 0 0 1 1 1 0 IncA protein SlyX PF04102.7 CAM71575.1 - 0.31 11.4 2.2 0.48 10.8 0.3 2.1 2 0 0 2 2 2 0 SlyX DUF605 PF04652.11 CAM71575.1 - 0.67 9.2 6.2 0.85 8.9 4.3 1.1 1 0 0 1 1 1 0 Vta1 like TMF_DNA_bd PF12329.3 CAM71575.1 - 0.91 9.3 5.6 0.43 10.4 1.4 2.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Dus PF01207.12 CAM71577.1 - 1.2e-52 178.6 0.1 3.8e-51 173.7 0.1 2.1 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 CAM71577.1 - 0.0079 15.4 0.0 0.025 13.8 0.0 1.8 2 0 0 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.9 CAM71577.1 - 0.0099 14.9 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG BMC PF00936.14 CAM71577.1 - 0.11 12.2 1.9 0.36 10.5 0.2 2.3 2 0 0 2 2 2 0 BMC domain DUF167 PF02594.11 CAM71579.1 - 1e-10 41.3 0.0 3.8e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised ACR, YggU family COG1872 HALZ PF02183.13 CAM71581.1 - 0.37 10.5 46.2 0.032 13.9 1.6 7.3 8 0 0 8 8 8 0 Homeobox associated leucine zipper HA2 PF04408.18 CAM71584.2 - 1.4e-15 57.1 0.0 8.9e-15 54.5 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.24 CAM71584.2 - 2.1e-10 40.3 0.2 5.8e-10 38.9 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM71584.2 - 3.5e-10 39.6 0.0 2.5e-09 36.8 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.20 CAM71584.2 - 0.00013 22.4 0.3 0.064 13.8 0.1 3.0 2 0 0 2 2 2 1 Double-stranded RNA binding motif AAA_22 PF13401.1 CAM71584.2 - 0.0005 20.2 0.0 0.0015 18.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.11 CAM71584.2 - 0.0054 16.5 0.0 0.11 12.3 0.0 2.5 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold T2SE PF00437.15 CAM71584.2 - 0.024 13.5 0.0 0.051 12.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Rad17 PF03215.10 CAM71584.2 - 0.19 10.4 0.0 0.3 9.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein F-box PF00646.28 CAM71586.1 - 0.042 13.5 0.5 0.075 12.7 0.3 1.4 1 0 0 1 1 1 0 F-box domain Exo_endo_phos PF03372.18 CAM71587.1 - 3.2e-16 60.0 0.5 7.6e-16 58.7 0.3 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HALZ PF02183.13 CAM71588.1 - 0.029 14.0 3.4 0.51 10.0 0.2 3.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF972 PF06156.8 CAM71588.1 - 0.049 13.9 1.6 0.16 12.3 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Shugoshin_N PF07558.6 CAM71588.1 - 0.11 12.2 2.3 0.34 10.6 0.8 2.2 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Vps51 PF08700.6 CAM71588.1 - 0.16 11.8 2.6 0.21 11.4 0.8 1.9 2 0 0 2 2 2 0 Vps51/Vps67 DUF1640 PF07798.6 CAM71588.1 - 0.27 11.2 3.7 0.84 9.6 2.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DivIC PF04977.10 CAM71588.1 - 2.9 7.4 5.7 13 5.3 1.0 2.6 2 0 0 2 2 2 0 Septum formation initiator DNA_pol_A_exo1 PF01612.15 CAM71589.1 - 2.3e-13 49.9 0.1 1.2e-12 47.7 0.0 2.1 2 1 0 2 2 2 1 3'-5' exonuclease zf-CCCH PF00642.19 CAM71589.1 - 0.0097 15.5 0.2 0.022 14.4 0.1 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TPR_15 PF13429.1 CAM71590.1 - 0.013 14.5 0.1 0.015 14.3 0.1 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat NIF PF03031.13 CAM71591.1 - 2.3e-30 105.3 0.3 1.7e-29 102.5 0.1 2.3 2 1 0 2 2 2 1 NLI interacting factor-like phosphatase DNA_pol_A PF00476.15 CAM71592.1 - 1.2e-68 231.5 0.0 8.9e-63 212.1 0.0 2.6 2 1 0 2 2 2 2 DNA polymerase family A DUF3595 PF12166.3 CAM71593.1 - 7.1e-116 387.4 0.0 9.4e-116 387.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3595) OsmC PF02566.14 CAM71596.1 - 9.1e-07 29.0 0.3 1.8e-06 28.0 0.2 1.5 1 0 0 1 1 1 1 OsmC-like protein BRF1 PF07741.8 CAM71596.1 - 0.34 11.1 2.9 0.85 9.8 2.0 1.6 1 0 0 1 1 1 0 Brf1-like TBP-binding domain IATP PF04568.7 CAM71596.1 - 0.89 9.6 9.5 1.7 8.6 0.3 3.1 3 1 1 4 4 4 0 Mitochondrial ATPase inhibitor, IATP BCS1_N PF08740.6 CAM71599.1 - 1.3e-35 122.7 2.6 1.6e-35 122.4 1.8 1.1 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 CAM71599.1 - 1.2e-06 28.7 0.0 2.8e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CAM71599.1 - 0.0023 17.9 0.1 0.0058 16.6 0.0 1.7 2 0 0 2 2 1 1 AAA ATPase domain ABC_tran PF00005.22 CAM71599.1 - 0.0026 18.0 0.0 0.0083 16.4 0.0 1.8 2 1 0 2 2 2 1 ABC transporter AAA_22 PF13401.1 CAM71599.1 - 0.0034 17.5 0.0 0.053 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CAM71599.1 - 0.0038 16.9 0.0 0.011 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CAM71599.1 - 0.0047 17.7 0.0 0.011 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CAM71599.1 - 0.0055 16.3 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CAM71599.1 - 0.0059 16.4 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CAM71599.1 - 0.0081 15.8 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 CAM71599.1 - 0.01 14.8 0.0 0.018 14.0 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 CAM71599.1 - 0.011 15.8 0.0 0.028 14.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 CAM71599.1 - 0.012 15.2 0.3 0.091 12.4 0.0 2.5 3 1 1 4 4 4 0 NACHT domain Rad17 PF03215.10 CAM71599.1 - 0.015 14.0 0.0 0.023 13.4 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_25 PF13481.1 CAM71599.1 - 0.018 14.4 0.0 0.056 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CAM71599.1 - 0.026 14.3 0.0 0.064 13.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 CAM71599.1 - 0.069 13.4 0.0 0.47 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.8 CAM71599.1 - 0.069 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus IstB_IS21 PF01695.12 CAM71599.1 - 0.1 12.0 0.0 0.26 10.6 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein Sfi1 PF08457.5 CAM71600.1 - 2.4 6.4 75.5 0.019 13.4 21.0 4.0 2 1 1 3 3 3 0 Sfi1 spindle body protein IncA PF04156.9 CAM71601.1 - 0.00055 19.5 0.8 0.0014 18.2 0.6 1.7 1 0 0 1 1 1 1 IncA protein DUF3166 PF11365.3 CAM71601.1 - 0.013 15.9 3.9 0.097 13.1 0.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3166) GAS PF13851.1 CAM71601.1 - 0.37 9.9 2.0 0.6 9.2 1.4 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Lzipper-MIP1 PF14389.1 CAM71601.1 - 1.9 8.6 5.9 57 3.9 2.9 3.0 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF572 PF04502.8 CAM71603.1 - 0.19 10.9 11.6 0.29 10.3 8.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) APG6 PF04111.7 CAM71603.1 - 0.67 8.9 11.6 0.96 8.4 8.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 TMA7 PF09072.5 CAM71603.1 - 0.99 9.9 0.1 0.99 9.9 0.0 3.3 4 1 1 5 5 5 0 Translation machinery associated TMA7 Mnd1 PF03962.10 CAM71603.1 - 2.8 7.5 10.1 5.5 6.6 7.0 1.5 1 0 0 1 1 1 0 Mnd1 family Cluap1 PF10234.4 CAM71603.1 - 4.7 6.3 14.7 1.8 7.7 7.4 2.0 1 1 1 2 2 2 0 Clusterin-associated protein-1 Asp-B-Hydro_N PF05279.6 CAM71603.1 - 6.7 6.4 8.8 10 5.8 6.1 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Chorein_N PF12624.2 CAM71605.2 - 1.1e-29 102.3 0.1 2.7e-29 101.1 0.0 1.7 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF1162 PF06650.7 CAM71605.2 - 1.9e-15 56.8 0.0 2.5e-13 49.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1162) 2-Hacid_dh_C PF02826.14 CAM71606.2 - 5.1e-39 133.2 0.0 5.7e-39 133.0 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 CAM71606.2 - 4.9e-06 26.4 0.1 6.7e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.1 CAM71606.2 - 8.8e-06 25.8 0.0 1.2e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding IlvN PF07991.7 CAM71606.2 - 2.9e-05 23.4 0.0 3.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 CAM71606.2 - 0.00048 20.5 0.1 0.00099 19.4 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.16 CAM71606.2 - 0.00078 19.3 0.5 0.0021 17.9 0.3 1.6 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.16 CAM71606.2 - 0.035 13.6 0.2 0.24 10.9 0.1 2.0 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 CAM71606.2 - 0.11 12.9 0.1 0.2 12.0 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Saccharop_dh PF03435.13 CAM71606.2 - 0.14 11.1 0.3 0.28 10.0 0.2 1.5 1 1 0 1 1 1 0 Saccharopine dehydrogenase DUF1143 PF06608.6 CAM71607.2 - 0.0078 16.2 0.0 0.033 14.1 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1143) PTEN_C2 PF10409.4 CAM71608.1 - 3.9e-11 42.8 0.0 6.4e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.15 CAM71608.1 - 6.5e-09 35.4 0.1 1.4e-08 34.4 0.1 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CAM71608.1 - 6.6e-05 22.3 0.1 0.00015 21.2 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CAM71608.1 - 0.0019 18.2 0.2 0.0051 16.8 0.0 1.8 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 CAM71608.1 - 0.002 18.3 0.5 0.004 17.4 0.4 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF3353 PF11833.3 CAM71608.1 - 0.013 14.9 0.5 0.022 14.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) R3H-assoc PF13902.1 CAM71610.1 - 1.7e-20 73.3 0.1 3.2e-20 72.4 0.1 1.5 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.17 CAM71610.1 - 0.00047 19.7 0.1 0.002 17.7 0.0 2.1 2 0 0 2 2 2 1 R3H domain PPR_2 PF13041.1 CAM71611.1 - 0.011 15.7 0.1 9.6 6.2 0.0 3.8 4 0 0 4 4 4 0 PPR repeat family PPR PF01535.15 CAM71611.1 - 0.09 12.7 0.0 12 6.1 0.0 2.9 2 0 0 2 2 2 0 PPR repeat EAP30 PF04157.11 CAM71612.1 - 3.4e-88 294.5 0.7 4.1e-88 294.2 0.5 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Nop25 PF09805.4 CAM71612.1 - 0.85 9.6 6.1 9.8 6.2 0.3 2.7 3 0 0 3 3 3 0 Nucleolar protein 12 (25kDa) YueH PF14166.1 CAM71614.1 - 0.11 12.2 0.9 8.5 6.2 0.0 2.8 3 0 0 3 3 3 0 YueH-like protein Opy2 PF09463.5 CAM71614.1 - 1.2 9.3 5.1 3.2 7.9 3.6 1.7 1 0 0 1 1 1 0 Opy2 protein DUF3808 PF10300.4 CAM71615.2 - 5.3e-43 147.2 1.5 1e-42 146.3 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) DUF4094 PF13334.1 CAM71616.1 - 0.033 14.5 0.4 0.2 12.0 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) MerR-DNA-bind PF09278.6 CAM71616.1 - 1.1 9.6 4.5 0.96 9.8 1.5 2.1 2 0 0 2 2 2 0 MerR, DNA binding p25-alpha PF05517.7 CAM71617.1 - 4e-48 163.5 5.2 4.4e-48 163.4 3.6 1.0 1 0 0 1 1 1 1 p25-alpha SCP-1 PF05483.7 CAM71617.1 - 0.047 11.4 0.1 0.057 11.2 0.1 1.0 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) p25-alpha PF05517.7 CAM71618.1 - 4.3e-40 137.4 4.7 5e-40 137.2 3.2 1.0 1 0 0 1 1 1 1 p25-alpha SCP-1 PF05483.7 CAM71618.1 - 0.07 10.8 0.1 0.084 10.6 0.1 1.0 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) Kinesin PF00225.18 CAM71619.1 - 5.9e-89 298.0 0.0 7.8e-89 297.6 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain TrwB_AAD_bind PF10412.4 CAM71619.1 - 0.0022 16.7 0.0 0.0042 15.7 0.0 1.4 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain Gag_spuma PF03276.9 CAM71619.1 - 0.044 12.1 5.1 0.085 11.1 3.5 1.4 1 0 0 1 1 1 0 Spumavirus gag protein AAA_23 PF13476.1 CAM71619.1 - 0.056 13.7 0.0 0.96 9.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.13 CAM71619.1 - 0.068 12.8 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein UQ_con PF00179.21 CAM71621.1 - 9.8e-22 76.8 0.0 1.1e-21 76.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CAM71621.1 - 0.013 15.1 0.0 0.025 14.3 0.0 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family B YjbR PF04237.8 CAM71621.1 - 0.048 14.0 0.5 1.5 9.1 0.2 2.3 1 1 1 2 2 2 0 YjbR Amastin PF07344.6 CAM71622.1 - 9.4e-57 190.9 11.4 1.7e-56 190.1 7.9 1.4 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CAM71622.1 - 2.7 7.6 22.6 0.13 11.9 7.7 2.1 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 CAM71623.1 - 6.1e-52 175.3 7.2 7.2e-52 175.1 5.0 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CAM71623.1 - 0.00069 19.3 12.9 0.0011 18.6 8.4 1.7 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Bap31 PF05529.7 CAM71623.1 - 0.094 12.1 0.5 0.42 10.0 0.0 2.1 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like DUF2708 PF10917.3 CAM71623.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2708) Amastin PF07344.6 CAM71624.1 - 2.6e-47 160.3 9.5 3.1e-47 160.0 6.6 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CAM71624.1 - 2.7e-05 23.9 16.5 5.8e-05 22.8 10.3 1.9 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 CAM71624.1 - 0.00061 19.4 7.0 0.00089 18.9 4.8 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family DUF754 PF05449.6 CAM71624.1 - 0.016 15.1 0.7 0.016 15.1 0.5 2.9 2 2 1 4 4 4 0 Protein of unknown function (DUF754) SP_C-Propep PF08999.5 CAM71624.1 - 1.2 8.6 11.5 2.1 7.8 0.1 3.2 2 1 1 3 3 3 0 Surfactant protein C, N terminal propeptide SUR7 PF06687.7 CAM71624.1 - 9.7 5.6 21.5 1.7e+02 1.6 14.4 2.2 1 1 0 1 1 1 0 SUR7/PalI family Amastin PF07344.6 CAM71625.1 - 3.8e-54 182.5 16.1 4.4e-54 182.2 11.1 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CAM71625.1 - 0.0023 17.6 12.7 0.0023 17.6 8.8 1.7 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 CAM71626.1 - 6e-51 172.1 11.0 7e-51 171.8 7.6 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CAM71626.1 - 0.00097 18.8 11.3 0.00097 18.8 7.8 1.7 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 CAM71628.2 - 1.4e-47 161.1 10.5 1.4e-47 161.1 7.3 1.6 2 0 0 2 2 2 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CAM71628.2 - 1.3 8.6 16.6 3.4 7.3 11.3 1.8 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 CAM71629.1 - 5.2e-51 172.3 13.1 6.4e-51 172.0 9.0 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.15 CAM71629.1 - 0.0076 15.9 12.0 0.012 15.2 8.3 1.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 CAM71629.1 - 0.51 10.0 16.8 0.021 14.4 7.4 1.8 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DuoxA PF10204.4 CAM71629.1 - 9.1 5.2 14.5 1.4 7.8 4.5 2.1 2 0 0 2 2 2 0 Dual oxidase maturation factor Zeta_toxin PF06414.7 CAM71630.1 - 5.8e-10 38.5 0.0 1.3e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 CAM71630.1 - 0.014 15.2 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Thioredoxin PF00085.15 CAM71630.1 - 0.017 14.7 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin AAA_18 PF13238.1 CAM71630.1 - 0.18 12.1 0.0 0.38 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Peptidase_C15 PF01470.12 CAM71631.1 - 3.2e-11 43.4 0.3 7.1e-05 22.7 0.0 2.3 2 0 0 2 2 2 2 Pyroglutamyl peptidase RCC1 PF00415.13 CAM71633.1 - 4.7e-24 84.3 1.5 6.1e-08 32.7 0.0 4.7 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CAM71633.1 - 7.5e-18 63.6 10.2 1.5e-10 40.3 1.3 5.5 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat IQ PF00612.22 CAM71634.1 - 1.7e-05 24.0 46.6 0.0065 16.0 0.6 7.5 7 0 0 7 7 7 6 IQ calmodulin-binding motif DEAD PF00270.24 CAM71636.1 - 5.7e-42 143.0 0.0 1.4e-41 141.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM71636.1 - 2.3e-20 72.2 0.0 5.1e-20 71.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 CAM71636.1 - 2.2e-08 33.7 3.7 4.7e-08 32.7 2.5 1.6 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.10 CAM71636.1 - 0.031 14.1 0.0 0.094 12.5 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Pkinase PF00069.20 CAM71640.1 - 4.9e-55 186.4 0.0 5.8e-55 186.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM71640.1 - 1.8e-30 105.9 0.0 2.4e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM71640.1 - 0.0013 17.7 0.0 0.0021 17.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 CAM71642.1 - 4.9e-43 147.1 0.0 7.8e-42 143.2 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM71642.1 - 1e-23 83.7 0.0 1.1e-20 73.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CAM71642.1 - 0.0094 14.9 0.0 0.02 13.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CAM71642.1 - 0.065 12.2 0.0 0.17 10.9 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family OGG_N PF07934.7 CAM71644.1 - 1.2e-29 102.6 0.0 1.9e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 CAM71644.1 - 9.8e-09 35.4 0.0 5.7e-08 33.0 0.0 2.0 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 CAM71644.1 - 0.00024 20.6 0.0 0.0029 17.2 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix motif Arm_2 PF04826.8 CAM71645.1 - 0.21 10.6 0.0 0.41 9.7 0.0 1.4 1 0 0 1 1 1 0 Armadillo-like Pkinase PF00069.20 CAM71646.2 - 6.9e-51 172.8 0.0 5.1e-26 91.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAM71646.2 - 4.1e-28 98.1 0.0 2.2e-15 56.4 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase DSPc PF00782.15 CAM71646.2 - 3.7e-27 94.5 0.0 9e-27 93.2 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain LRR_4 PF12799.2 CAM71646.2 - 2.9e-11 42.6 15.2 5.8e-07 28.9 0.6 3.5 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CAM71646.2 - 9.3e-08 31.0 9.5 0.13 12.4 0.1 6.2 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_8 PF13855.1 CAM71646.2 - 1.8e-07 30.7 10.3 9.4e-07 28.5 3.1 3.6 2 1 1 3 3 3 2 Leucine rich repeat LRR_7 PF13504.1 CAM71646.2 - 1e-05 24.9 3.3 0.62 10.5 0.0 5.3 4 0 0 4 4 4 1 Leucine rich repeat Y_phosphatase PF00102.22 CAM71646.2 - 0.00024 20.5 0.0 0.00067 19.0 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DUF3451 PF11933.3 CAM71646.2 - 0.39 10.4 5.8 6.1 6.5 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3451) Thioredoxin PF00085.15 CAM71647.1 - 2.5e-27 94.5 0.0 1.1e-26 92.5 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 CAM71647.1 - 1.9e-10 40.9 0.2 6.8e-09 35.9 0.0 3.3 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CAM71647.1 - 6.2e-08 32.6 0.0 2.5e-06 27.5 0.0 3.1 4 0 0 4 4 4 1 Thioredoxin-like Thioredoxin_6 PF13848.1 CAM71647.1 - 6e-06 26.1 0.0 0.00057 19.7 0.0 2.9 3 1 1 4 4 4 1 Thioredoxin-like domain Redoxin PF08534.5 CAM71647.1 - 0.00021 20.8 0.2 0.002 17.6 0.0 2.6 2 1 1 3 3 3 1 Redoxin AhpC-TSA PF00578.16 CAM71647.1 - 0.00076 19.1 0.0 0.0048 16.5 0.0 2.2 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_7 PF13899.1 CAM71647.1 - 0.0013 18.6 0.0 0.004 17.1 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 CAM71647.1 - 0.0029 17.1 0.0 0.0067 15.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_4 PF13462.1 CAM71647.1 - 0.012 15.6 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin Exo_endo_phos PF03372.18 CAM71649.2 - 1.7e-13 51.1 0.0 3.6e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TLC PF03219.9 CAM71650.1 - 0.025 13.0 0.8 0.033 12.6 0.6 1.1 1 0 0 1 1 1 0 TLC ATP/ADP transporter Glyco_hydro_65m PF03632.10 CAM71651.1 - 4.6e-38 130.8 0.0 7.4e-38 130.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65C PF03633.10 CAM71651.1 - 1.2e-07 31.6 0.0 2.6e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain HAD_2 PF13419.1 CAM71651.1 - 0.00094 19.4 0.0 0.0044 17.2 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Kelch_4 PF13418.1 CAM71652.2 - 3e-12 46.1 10.5 6.9e-06 25.7 0.0 5.9 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.1 CAM71652.2 - 1.6e-11 44.0 22.5 9.4e-06 25.6 0.0 8.6 9 1 0 9 9 9 3 Galactose oxidase, central domain Kelch_5 PF13854.1 CAM71652.2 - 5.9e-10 38.8 9.4 0.00021 21.1 0.2 6.3 7 0 0 7 7 7 3 Kelch motif Kelch_1 PF01344.20 CAM71652.2 - 2.8e-09 36.3 4.7 0.00033 20.1 0.0 4.1 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 CAM71652.2 - 2.7e-08 33.6 2.0 0.043 14.0 0.0 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 CAM71652.2 - 0.0014 18.3 5.2 5 7.0 0.0 5.4 5 0 0 5 5 5 1 Kelch motif DUF1091 PF06477.8 CAM71653.1 - 0.039 14.3 0.1 8 6.9 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1091) Aminotran_4 PF01063.14 CAM71654.1 - 2.3e-24 86.1 0.0 3.2e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Glycos_transf_1 PF00534.15 CAM71655.1 - 3.4e-27 94.9 0.0 5.7e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CAM71655.1 - 1.8e-07 31.3 0.0 4.1e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CAM71655.1 - 0.00068 19.8 0.0 0.0031 17.7 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 TPR_11 PF13414.1 CAM71656.1 - 7.7e-28 95.9 20.7 3e-12 45.9 1.0 4.8 3 2 1 4 4 4 3 TPR repeat DnaJ PF00226.26 CAM71656.1 - 2.6e-20 71.9 0.1 6.4e-20 70.6 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.23 CAM71656.1 - 5.8e-17 60.5 16.0 1.2e-05 24.6 0.1 6.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 CAM71656.1 - 1.6e-14 52.5 26.1 0.00055 19.6 0.3 7.6 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 CAM71656.1 - 1.7e-07 31.7 9.6 0.091 13.4 0.4 6.7 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 CAM71656.1 - 8.6e-06 25.6 0.9 8.6e-06 25.6 0.6 5.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 CAM71656.1 - 0.00033 20.2 14.3 0.0091 15.7 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 CAM71656.1 - 0.0013 18.7 0.4 27 5.3 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Rapsyn_N PF10579.4 CAM71656.1 - 0.003 17.3 1.0 0.19 11.5 0.0 3.0 2 1 1 3 3 3 1 Rapsyn N-terminal myristoylation and linker region TPR_14 PF13428.1 CAM71656.1 - 0.024 15.2 13.6 1.1 10.0 0.6 6.7 4 2 4 8 8 7 0 Tetratricopeptide repeat Apc3 PF12895.2 CAM71656.1 - 0.038 14.1 15.5 0.32 11.1 0.3 4.4 3 2 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4124 PF13511.1 CAM71656.1 - 0.053 13.5 0.2 0.053 13.5 0.1 2.8 3 0 0 3 3 2 0 Domain of unknown function (DUF4124) TPR_9 PF13371.1 CAM71656.1 - 0.056 13.3 4.1 1.6 8.6 0.2 3.3 2 1 1 3 3 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 CAM71656.1 - 0.15 11.9 10.1 9.7 6.2 0.0 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 CAM71656.1 - 2.3 8.8 11.4 5.1 7.7 0.0 5.9 7 0 0 7 7 6 0 Tetratricopeptide repeat Dsh_C PF12316.3 CAM71657.1 - 0.016 15.3 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal C1_1 PF00130.17 CAM71657.1 - 0.089 12.5 0.7 0.089 12.5 0.5 1.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Sec7 PF01369.15 CAM71658.1 - 8.6e-52 175.5 0.0 1.4e-51 174.9 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 CAM71658.1 - 0.0017 17.8 0.8 0.95 8.8 0.3 2.8 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal EF-hand_7 PF13499.1 CAM71659.1 - 3.2e-22 78.4 4.1 5.1e-14 52.1 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CAM71659.1 - 3.5e-22 75.9 6.5 1.3e-07 30.3 0.9 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 CAM71659.1 - 5.1e-20 69.5 4.0 2.5e-06 26.8 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 CAM71659.1 - 2.1e-15 56.0 10.9 1.2e-12 47.1 0.8 3.7 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 CAM71659.1 - 2.1e-14 52.1 4.2 0.00048 19.3 0.5 3.5 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.1 CAM71659.1 - 4.7e-12 45.6 0.3 3.7e-06 26.7 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CAM71659.1 - 8.9e-07 28.6 0.5 0.004 16.8 0.1 2.2 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF3164 PF11363.3 CAM71659.1 - 0.0035 16.7 0.9 0.13 11.5 0.0 2.4 1 1 0 2 2 2 1 Protein of unknown function (DUF3164) Caleosin PF05042.8 CAM71659.1 - 0.026 14.0 0.1 0.26 10.8 0.0 2.2 2 1 1 3 3 3 0 Caleosin related protein MgtE_N PF03448.12 CAM71659.1 - 0.03 14.6 0.7 0.03 14.6 0.5 2.5 3 0 0 3 3 3 0 MgtE intracellular N domain TerB PF05099.8 CAM71659.1 - 0.05 13.3 6.3 0.27 10.9 1.0 2.7 1 1 3 4 4 4 0 Tellurite resistance protein TerB SPARC_Ca_bdg PF10591.4 CAM71659.1 - 0.075 13.0 2.0 1.5 8.8 0.3 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region LTXXQ PF07813.7 CAM71659.1 - 0.53 10.7 6.3 8.5 6.8 4.4 2.2 1 1 0 1 1 1 0 LTXXQ motif family protein HA2 PF04408.18 CAM71661.2 - 5.9e-17 61.5 0.0 1.1e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CAM71661.2 - 3.3e-12 46.1 0.0 9.3e-12 44.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 CAM71661.2 - 2.9e-11 43.2 0.0 7.3e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 CAM71661.2 - 5.7e-08 32.4 0.7 5.4e-07 29.2 0.3 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CAM71661.2 - 3.3e-06 27.2 0.0 1.1e-05 25.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CAM71661.2 - 0.00023 20.6 0.0 0.00056 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 CAM71661.2 - 0.00038 19.9 0.1 0.0011 18.4 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain T2SE PF00437.15 CAM71661.2 - 0.00094 18.1 0.0 0.0019 17.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 CAM71661.2 - 0.004 17.0 0.0 1.8 8.3 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_29 PF13555.1 CAM71661.2 - 0.0054 16.2 0.0 0.015 14.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 CAM71661.2 - 0.0092 15.9 2.3 0.13 12.2 0.5 3.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 CAM71661.2 - 0.013 15.2 0.4 0.013 15.2 0.3 3.5 3 0 0 3 3 3 0 Part of AAA domain cobW PF02492.14 CAM71661.2 - 0.024 14.0 0.0 0.64 9.4 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 CAM71661.2 - 0.028 14.7 0.0 0.098 12.9 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.1 CAM71661.2 - 0.031 13.8 0.0 0.075 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 CAM71661.2 - 0.075 13.2 0.0 0.54 10.4 0.0 2.5 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Flavi_DEAD PF07652.9 CAM71661.2 - 0.093 12.4 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain KaiC PF06745.8 CAM71661.2 - 0.12 11.4 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.1 CAM71661.2 - 0.21 11.8 0.0 0.39 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CAM71661.2 - 0.26 10.9 2.0 0.99 9.0 0.1 2.9 3 1 0 3 3 2 0 NACHT domain Dynamin_N PF00350.18 CAM71662.1 - 5.1e-18 65.4 0.0 4.5e-12 46.1 0.0 2.6 3 0 0 3 3 3 2 Dynamin family MMR_HSR1 PF01926.18 CAM71662.1 - 8.2e-09 35.4 0.0 2e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_10 PF12846.2 CAM71662.1 - 0.49 9.7 3.0 2.4 7.5 0.0 2.9 3 0 0 3 3 3 0 AAA-like domain Cofilin_ADF PF00241.15 CAM71664.1 - 5.5e-11 42.4 0.1 2.1e-07 30.8 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein MMgT PF10270.4 CAM71667.1 - 0.003 17.9 4.0 0.02 15.2 2.8 2.3 1 1 0 1 1 1 1 Membrane magnesium transporter Clat_adaptor_s PF01217.15 CAM71668.1 - 4.1e-50 169.2 4.4 4.5e-50 169.0 3.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain tRNA-synt_2 PF00152.15 CAM71669.1 - 4.5e-70 236.0 0.0 6.2e-70 235.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_synt_1c_R1 PF04558.10 CAM71669.1 - 1.1e-43 148.5 0.3 2e-43 147.7 0.2 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_anti-codon PF01336.20 CAM71669.1 - 1.1e-10 41.1 0.0 2.6e-10 39.9 0.0 1.6 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain DUF4206 PF13901.1 CAM71669.1 - 0.076 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) DUF2046 PF09755.4 CAM71671.1 - 3.7e-06 26.0 19.8 3.7e-06 26.0 13.7 3.0 3 1 0 3 3 3 1 Uncharacterized conserved protein H4 (DUF2046) TrmB PF01978.14 CAM71671.1 - 0.13 11.9 2.1 0.19 11.4 0.5 2.0 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Phage_B PF02304.10 CAM71671.1 - 0.95 9.7 4.1 1.6 9.0 0.0 2.9 2 1 1 3 3 3 0 Scaffold protein B CBFD_NFYB_HMF PF00808.18 CAM71672.1 - 2e-06 27.7 0.4 3.2e-06 27.1 0.3 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CAM71672.1 - 0.00013 22.0 0.8 0.00026 21.0 0.5 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF1931 PF09123.6 CAM71672.1 - 0.071 13.0 0.1 0.18 11.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1931) DUF2890 PF11081.3 CAM71672.1 - 0.46 10.5 5.3 0.09 12.8 1.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) GTP_EFTU PF00009.22 CAM71673.1 - 8e-08 31.9 0.0 1.6e-07 30.9 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 CAM71673.1 - 0.013 15.0 2.3 0.41 10.1 0.3 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein GTP_EFTU_D2 PF03144.20 CAM71673.1 - 0.034 14.2 0.1 0.099 12.7 0.1 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 2 AAA_29 PF13555.1 CAM71673.1 - 0.047 13.2 0.2 0.12 11.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 CAM71673.1 - 0.059 13.6 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_10 PF12846.2 CAM71673.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain PduV-EutP PF10662.4 CAM71673.1 - 0.25 10.8 0.3 9.6 5.6 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ribosomal_L35Ae PF01247.13 CAM71674.1 - 3.2e-35 119.7 1.6 4.6e-35 119.2 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 CAM71674.1 - 7.2e-05 22.6 0.4 0.088 12.7 0.0 2.4 2 1 0 2 2 2 2 RimM N-terminal domain DUF3382 PF11862.3 CAM71676.1 - 0.033 14.0 3.0 0.067 13.1 1.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3382) DUF1469 PF07332.6 CAM71676.1 - 0.39 10.4 3.5 0.72 9.6 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) CENP-F_leu_zip PF10473.4 CAM71678.1 - 0.0004 20.2 17.3 0.0004 20.2 12.0 8.3 2 2 6 8 8 8 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 M PF02370.11 CAM71678.1 - 0.19 12.1 10.1 8.5 7.1 1.5 5.2 2 0 0 2 2 2 0 M protein repeat LRR_6 PF13516.1 CAM71679.1 - 2.6e-07 29.9 0.8 0.14 12.3 0.0 4.6 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.28 CAM71679.1 - 0.011 15.5 1.8 7.8 6.9 0.0 3.5 4 0 0 4 4 4 0 Leucine Rich Repeat BRX PF08381.6 CAM71679.1 - 0.035 13.1 0.0 0.068 12.2 0.0 1.4 1 0 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 WD40 PF00400.27 CAM71680.1 - 0.36 10.7 0.1 0.36 10.7 0.0 5.1 6 0 0 6 6 6 0 WD domain, G-beta repeat PP2C PF00481.16 CAM71681.1 - 2.8e-53 180.9 0.0 3.5e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CAM71681.1 - 0.00048 19.5 0.0 0.0012 18.2 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 CAM71682.2 - 1.5e-56 191.6 0.0 1.9e-56 191.3 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CAM71682.2 - 0.056 12.8 0.0 0.16 11.3 0.0 1.7 1 1 0 1 1 1 0 Protein phosphatase 2C Sec7 PF01369.15 CAM71684.1 - 2.8e-49 167.3 0.0 4.1e-48 163.5 0.0 2.3 2 0 0 2 2 2 1 Sec7 domain DUF1981 PF09324.5 CAM71684.1 - 3.1e-21 74.6 0.3 1.8e-20 72.2 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) Sec7_N PF12783.2 CAM71684.1 - 1.4e-19 70.1 0.2 5e-19 68.3 0.1 2.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Cluap1 PF10234.4 CAM71685.2 - 0.0074 15.5 1.0 0.0074 15.5 0.7 8.0 8 3 2 10 10 10 1 Clusterin-associated protein-1 SpoIISA_toxin PF14171.1 CAM71685.2 - 0.11 11.6 0.0 0.11 11.6 0.0 1.7 2 0 0 2 2 2 0 Toxin SpoIISA, type II toxin-antitoxin system SlyX PF04102.7 CAM71685.2 - 1.5 9.2 67.0 30 5.0 0.1 13.6 13 0 0 13 13 13 0 SlyX Reo_sigmaC PF04582.7 CAM71685.2 - 2.1 7.4 25.4 0.47 9.5 0.8 6.7 6 0 0 6 6 6 0 Reovirus sigma C capsid protein FlaC_arch PF05377.6 CAM71685.2 - 7.8 6.4 31.5 0.77 9.6 0.6 11.0 12 1 0 12 12 12 0 Flagella accessory protein C (FlaC) Shugoshin_N PF07558.6 CAM71686.2 - 0.00061 19.4 22.0 0.21 11.3 0.1 8.1 7 1 1 8 8 8 2 Shugoshin N-terminal coiled-coil region C2 PF00168.25 CAM71686.2 - 0.0074 16.1 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain YkyA PF10368.4 CAM71687.1 - 0.014 14.6 1.7 0.014 14.6 1.2 2.7 3 0 0 3 3 3 0 Putative cell-wall binding lipoprotein LemA PF04011.7 CAM71687.1 - 0.078 12.0 0.8 0.18 10.8 0.5 1.5 1 0 0 1 1 1 0 LemA family FH2 PF02181.18 CAM71688.1 - 0.89 8.3 17.2 0.5 9.2 1.1 3.6 2 0 0 2 2 2 0 Formin Homology 2 Domain DNA_ligase_ZBD PF03119.11 CAM71688.1 - 2.3 8.0 19.0 60 3.4 0.2 6.0 5 0 0 5 5 5 0 NAD-dependent DNA ligase C4 zinc finger domain Corona_S2 PF01601.11 CAM71689.1 - 0.0076 14.4 0.1 0.018 13.1 0.1 1.6 1 0 0 1 1 1 1 Coronavirus S2 glycoprotein Alba PF01918.16 CAM71690.1 - 3.1e-14 52.3 0.2 4.4e-14 51.8 0.1 1.2 1 0 0 1 1 1 1 Alba Rpp20 PF12328.3 CAM71690.1 - 0.0027 17.3 0.1 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Adap_comp_sub PF00928.16 CAM71691.1 - 5.7e-55 186.2 0.0 7e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CAM71691.1 - 0.00021 21.0 0.0 0.00034 20.3 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ACBP PF00887.14 CAM71692.1 - 8e-20 70.3 0.5 8.8e-20 70.1 0.3 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein TIP49 PF06068.8 CAM71693.1 - 9.6e-179 594.2 2.2 9.6e-179 594.2 1.5 1.5 2 0 0 2 2 2 1 TIP49 C-terminus AAA PF00004.24 CAM71693.1 - 1.8e-08 34.6 1.8 8.4e-06 26.0 0.1 3.1 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CAM71693.1 - 2.9e-07 30.7 1.0 0.05 13.7 0.2 3.2 2 1 1 3 3 3 2 AAA domain RuvB_N PF05496.7 CAM71693.1 - 3e-07 29.7 1.0 0.00022 20.3 0.0 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 CAM71693.1 - 6.7e-06 25.8 0.3 0.0014 18.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CAM71693.1 - 8.9e-06 25.8 0.1 4.9e-05 23.3 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.10 CAM71693.1 - 1.5e-05 24.0 0.1 2.8e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Mg_chelatase PF01078.16 CAM71693.1 - 2.6e-05 23.4 1.3 0.00054 19.1 0.5 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 CAM71693.1 - 0.00032 20.3 0.1 0.00083 19.0 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 CAM71693.1 - 0.00051 19.5 0.5 0.017 14.6 0.1 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_25 PF13481.1 CAM71693.1 - 0.00071 19.0 0.0 0.002 17.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CAM71693.1 - 0.001 18.2 0.3 0.0028 16.7 0.2 1.7 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 CAM71693.1 - 0.0037 16.7 0.0 1.4 8.3 0.1 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain CPT PF07931.7 CAM71693.1 - 0.0044 16.6 0.3 0.018 14.6 0.1 2.3 2 1 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein Sigma54_activ_2 PF14532.1 CAM71693.1 - 0.0077 16.2 0.1 0.61 10.1 0.0 2.9 3 0 0 3 3 3 1 Sigma-54 interaction domain NACHT PF05729.7 CAM71693.1 - 0.0089 15.7 0.0 0.025 14.2 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.1 CAM71693.1 - 0.012 15.1 0.2 0.034 13.6 0.1 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_28 PF13521.1 CAM71693.1 - 0.013 15.4 0.1 0.03 14.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 CAM71693.1 - 0.015 14.4 1.9 0.015 14.4 0.2 1.9 2 0 0 2 2 2 0 KaiC AAA_17 PF13207.1 CAM71693.1 - 0.016 16.0 0.1 0.072 13.9 0.0 2.2 3 0 0 3 3 1 0 AAA domain AAA_23 PF13476.1 CAM71693.1 - 0.022 15.0 0.1 0.043 14.1 0.0 1.6 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.12 CAM71693.1 - 0.023 14.1 1.2 0.037 13.4 0.2 1.7 2 0 0 2 2 1 0 IstB-like ATP binding protein DUF2075 PF09848.4 CAM71693.1 - 0.027 13.4 0.0 0.043 12.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) UPF0079 PF02367.12 CAM71693.1 - 0.029 14.0 0.1 0.08 12.5 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Parvo_NS1 PF01057.12 CAM71693.1 - 0.055 12.3 0.2 0.11 11.3 0.1 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_18 PF13238.1 CAM71693.1 - 0.058 13.6 0.0 0.16 12.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.22 CAM71693.1 - 0.079 13.2 0.2 0.17 12.1 0.1 1.6 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 CAM71693.1 - 0.094 12.5 0.1 0.27 11.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain SUV3_C PF12513.3 CAM71694.1 - 1.6e-11 43.4 0.1 3.8e-11 42.2 0.1 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 CAM71694.1 - 4.2e-06 26.5 0.0 9e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAM71694.1 - 0.0017 17.8 0.0 0.0067 15.9 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase Kinesin PF00225.18 CAM71694.1 - 0.033 12.8 0.0 0.051 12.2 0.0 1.2 1 0 0 1 1 1 0 Kinesin motor domain Hydrolase PF00702.21 CAM71695.1 - 2e-15 57.7 3.7 7.7e-09 36.2 1.8 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CAM71695.1 - 2.1e-11 43.3 0.2 1.3e-05 24.3 0.0 2.8 2 0 0 2 2 2 2 E1-E2 ATPase HAD PF12710.2 CAM71695.1 - 4.1e-11 43.4 1.3 4.4e-10 40.0 0.9 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CAM71695.1 - 1.4e-10 40.9 0.0 7.2e-10 38.6 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CAM71695.1 - 0.0011 18.6 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CAM71695.1 - 0.0078 16.4 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 CAM71695.1 - 0.13 12.1 0.0 0.61 10.0 0.0 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF4392 PF14336.1 CAM71695.1 - 0.21 10.3 0.0 0.35 9.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) DUF21 PF01595.15 CAM71697.1 - 8.1e-33 113.2 1.5 8.1e-33 113.2 1.1 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF21 CBS PF00571.23 CAM71697.1 - 3.9e-07 29.7 0.2 0.0068 16.1 0.1 2.6 2 0 0 2 2 2 2 CBS domain cNMP_binding PF00027.24 CAM71697.1 - 0.011 15.5 0.0 0.028 14.2 0.0 1.7 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Vps52 PF04129.7 CAM71698.1 - 1.1e-15 57.2 1.0 1.4e-14 53.5 0.3 2.1 2 0 0 2 2 2 1 Vps52 / Sac2 family Sec3_C PF09763.4 CAM71698.1 - 4.7e-05 21.7 0.2 0.04 12.0 0.0 2.2 2 0 0 2 2 2 2 Exocyst complex component Sec3 Tropomyosin_1 PF12718.2 CAM71698.1 - 0.28 11.0 1.4 0.8 9.5 1.0 1.8 1 0 0 1 1 1 0 Tropomyosin like ATG16 PF08614.6 CAM71698.1 - 0.41 10.4 7.1 0.24 11.2 0.8 2.7 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) FAD_binding_1 PF00667.15 CAM71699.1 - 6.1e-35 120.6 0.0 8.1e-35 120.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CAM71699.1 - 1.4e-23 83.4 0.0 3.1e-23 82.3 0.0 1.6 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 CAM71699.1 - 2.5e-17 63.4 0.0 4.7e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain WD40 PF00400.27 CAM71700.1 - 1.8e-24 84.6 3.6 9.5e-07 28.4 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat Dscam_C PF12355.3 CAM71700.1 - 0.1 12.8 1.5 0.15 12.3 0.4 1.7 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal Nup160 PF11715.3 CAM71700.1 - 0.12 10.4 0.1 0.61 8.1 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 R_equi_Vir PF05526.6 CAM71700.1 - 0.17 11.5 4.1 4.6 6.8 0.0 3.6 4 0 0 4 4 4 0 Rhodococcus equi virulence-associated protein RRM_1 PF00076.17 CAM71702.1 - 1.1e-11 44.1 0.0 2.4e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM71702.1 - 5.6e-09 35.8 0.0 9.5e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.3 CAM71702.1 - 0.00013 21.8 0.3 0.00031 20.6 0.0 1.8 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G MFS_1 PF07690.11 CAM71704.1 - 1.4e-21 76.6 24.0 2.4e-11 42.9 6.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily WBS_methylT PF12589.3 CAM71707.1 - 3.3e-10 40.3 15.2 1e-09 38.7 10.3 2.1 1 1 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 CAM71707.1 - 8.3e-09 35.8 0.0 0.0003 21.2 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 CAM71707.1 - 1.5e-05 24.6 0.0 0.00022 20.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAM71707.1 - 0.00015 22.1 0.0 0.00076 19.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAM71707.1 - 0.00028 21.3 0.0 0.017 15.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAM71707.1 - 0.0006 20.3 0.0 0.0011 19.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAM71707.1 - 0.002 17.8 0.0 0.0043 16.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain NOA36 PF06524.7 CAM71707.1 - 0.27 10.4 15.9 0.077 12.2 0.9 2.6 3 0 0 3 3 3 0 NOA36 protein FAM176 PF14851.1 CAM71708.1 - 0.2 11.3 4.8 0.54 9.9 0.0 2.3 2 0 0 2 2 2 0 FAM176 family Metallophos PF00149.23 CAM71710.1 - 6.3e-21 74.6 0.0 1.1e-17 64.1 0.0 2.5 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase Ribosomal_S19e PF01090.14 CAM71711.1 - 2.5e-45 153.3 0.0 3e-45 153.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19e SRP54 PF00448.17 CAM71712.1 - 0.035 13.5 0.1 0.27 10.6 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain TPR_8 PF13181.1 CAM71712.1 - 0.061 13.1 0.1 4.6 7.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 CAM71712.1 - 0.065 13.1 0.5 0.065 13.1 0.3 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 CAM71712.1 - 0.9 9.5 6.1 1.1 9.2 0.5 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_16 PF13191.1 CAM71713.1 - 2.3e-06 27.7 0.1 5.7e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CAM71713.1 - 8.6e-05 22.6 0.2 0.00037 20.6 0.0 2.2 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 CAM71713.1 - 0.001 18.9 0.1 0.0044 16.9 0.0 2.1 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 CAM71713.1 - 0.022 14.4 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Viral_helicase1 PF01443.13 CAM71713.1 - 0.036 13.5 0.1 0.087 12.3 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.1 CAM71713.1 - 0.051 13.4 0.0 0.051 13.4 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 CAM71713.1 - 0.053 14.3 0.0 0.18 12.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 CAM71713.1 - 0.09 12.4 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 CAM71713.1 - 0.09 13.0 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Adeno_IVa2 PF02456.10 CAM71713.1 - 0.16 10.5 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein Amastin PF07344.6 CAM71715.1 - 1.9e-48 164.0 7.2 1.9e-48 164.0 5.0 1.7 2 0 0 2 2 2 1 Amastin surface glycoprotein DUF4337 PF14235.1 CAM71715.1 - 0.0031 17.3 0.6 0.0049 16.7 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4337) Claudin_2 PF13903.1 CAM71715.1 - 0.088 12.4 17.8 0.033 13.8 7.4 2.5 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 CAM71715.1 - 3.4 7.3 12.4 16 5.1 7.1 2.7 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin family Peptidase_M14 PF00246.19 CAM71716.1 - 1.3e-26 93.8 0.0 3e-26 92.6 0.0 1.6 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.9 CAM71716.1 - 0.00042 19.2 0.1 0.00068 18.5 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.3 CAM71716.1 - 0.018 14.1 0.1 0.031 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) cNMP_binding PF00027.24 CAM71717.1 - 6e-24 83.6 0.1 2.3e-12 46.5 0.1 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.6 CAM71717.1 - 0.0031 16.9 0.3 0.011 15.2 0.1 1.9 2 0 0 2 2 2 1 Cupin domain Urm1 PF09138.6 CAM71718.1 - 4.4e-25 87.6 0.0 5e-25 87.4 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 CAM71718.1 - 7.6e-08 32.6 0.3 9.3e-08 32.3 0.2 1.2 1 0 0 1 1 1 1 ThiS family TGS PF02824.16 CAM71718.1 - 0.0048 16.7 0.4 0.012 15.3 0.2 1.7 2 0 0 2 2 2 1 TGS domain GTP_EFTU PF00009.22 CAM71719.1 - 8.4e-31 106.8 0.1 1.2e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 CAM71719.1 - 1.7e-08 34.4 0.3 5.1e-08 32.9 0.3 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CAM71719.1 - 2e-07 30.9 0.0 4.8e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 CAM71719.1 - 1.9e-05 24.2 0.0 5.3e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 SRPRB PF09439.5 CAM71719.1 - 0.00043 19.5 0.5 0.0058 15.8 0.1 2.5 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 CAM71719.1 - 0.0021 17.5 0.1 2.5 7.5 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 CAM71719.1 - 0.013 15.9 0.0 0.027 14.9 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein cobW PF02492.14 CAM71719.1 - 0.057 12.8 2.6 0.09 12.2 0.3 2.2 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 CAM71719.1 - 0.058 12.9 0.0 1.3 8.4 0.0 2.7 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Arf PF00025.16 CAM71719.1 - 0.12 11.5 0.0 0.27 10.4 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family Hexapep PF00132.19 CAM71720.1 - 2e-11 42.8 11.7 1.2e-07 30.8 0.6 3.2 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CAM71720.1 - 6.2e-05 22.4 9.4 0.038 13.5 0.8 3.0 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase HTH_Tnp_Tc3_2 PF01498.13 CAM71721.1 - 0.052 13.6 0.2 0.12 12.4 0.0 1.7 2 0 0 2 2 2 0 Transposase SAS4 PF15460.1 CAM71721.1 - 0.082 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 Ribosomal_L3 PF00297.17 CAM71722.1 - 3.2e-100 334.8 9.5 3.9e-100 334.5 6.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 Patatin PF01734.17 CAM71723.1 - 5.2e-09 36.3 1.0 4.1e-07 30.1 0.7 2.4 1 1 0 1 1 1 1 Patatin-like phospholipase EF-hand_1 PF00036.27 CAM71727.1 - 5.5e-14 50.3 0.0 8.4e-05 21.5 0.0 6.3 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.1 CAM71727.1 - 1.6e-13 49.3 0.1 0.0014 18.3 0.0 6.8 7 0 0 7 7 7 3 EF-hand domain EF-hand_8 PF13833.1 CAM71727.1 - 3.2e-13 49.0 0.1 2.1e-09 36.8 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.1 CAM71727.1 - 6.7e-13 48.5 0.0 2.6e-06 27.4 0.0 4.4 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 CAM71727.1 - 2.1e-11 42.5 0.5 0.056 12.8 0.0 5.9 6 0 0 6 6 6 3 EF hand EF-hand_10 PF14788.1 CAM71727.1 - 0.042 13.5 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 EF hand Spc7 PF08317.6 CAM71729.1 - 0.0013 17.5 10.9 0.0016 17.1 7.6 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF2281 PF10047.4 CAM71729.1 - 0.057 13.7 0.2 3.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2281) V_ATPase_I PF01496.14 CAM71729.1 - 0.13 10.1 3.1 0.17 9.6 2.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 CAM71729.1 - 0.43 9.5 11.8 0.58 9.1 8.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 SseC PF04888.7 CAM71729.1 - 0.93 8.7 7.0 0.25 10.6 2.7 1.5 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family DivIC PF04977.10 CAM71729.1 - 1.1 8.7 18.4 0.19 11.2 4.9 2.7 1 1 1 2 2 2 0 Septum formation initiator Exonuc_VII_L PF02601.10 CAM71729.1 - 1.4 8.0 8.4 1.7 7.7 5.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3287 PF11690.3 CAM71729.1 - 1.9 8.5 11.2 0.5 10.4 3.6 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3287) Nup88 PF10168.4 CAM71729.1 - 2 6.1 11.8 2.7 5.7 8.2 1.1 1 0 0 1 1 1 0 Nuclear pore component ADIP PF11559.3 CAM71729.1 - 2.5 8.0 19.1 5.8 6.8 13.3 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 CAM71729.1 - 4.8 6.7 15.7 1.3e+02 2.0 10.9 2.1 1 1 0 1 1 1 0 IncA protein DUF4200 PF13863.1 CAM71729.1 - 8 6.4 20.2 11 6.0 14.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) NDK PF00334.14 CAM71730.1 - 6.6e-15 55.0 0.0 7.3e-14 51.7 0.0 2.3 2 1 0 2 2 2 1 Nucleoside diphosphate kinase LRR_6 PF13516.1 CAM71731.1 - 0.002 17.9 0.1 0.24 11.5 0.0 2.9 2 0 0 2 2 2 1 Leucine Rich repeat CENP-B_dimeris PF09026.5 CAM71731.1 - 0.0031 17.7 0.0 0.0081 16.3 0.0 1.7 1 0 0 1 1 1 1 Centromere protein B dimerisation domain LRR_1 PF00560.28 CAM71731.1 - 0.028 14.3 0.0 0.24 11.5 0.0 2.6 2 0 0 2 2 2 0 Leucine Rich Repeat HTH_32 PF13565.1 CAM71731.1 - 0.044 14.5 0.2 0.54 11.1 0.0 2.6 2 0 0 2 2 2 0 Homeodomain-like domain LRR_4 PF12799.2 CAM71731.1 - 0.11 12.1 0.0 0.3 10.7 0.0 1.8 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) PNRC PF15365.1 CAM71732.1 - 0.18 11.8 0.1 0.18 11.8 0.0 3.0 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator Rhodanese PF00581.15 CAM71733.1 - 7.3e-11 42.4 0.0 1.3e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Methyltransf_31 PF13847.1 CAM71733.1 - 0.098 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 CAM71734.1 - 1.5e-23 83.2 0.0 2.3e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RMP PF14996.1 CAM71735.1 - 7.7e-09 35.6 6.0 7.7e-09 35.6 4.1 3.2 3 1 0 3 3 3 1 Retinal Maintenance Adeno_E1B_55K PF01696.12 CAM71736.1 - 0.00076 18.0 0.6 0.00076 18.0 0.4 2.1 2 0 0 2 2 2 1 Adenovirus EB1 55K protein / large t-antigen Beta_helix PF13229.1 CAM71736.1 - 0.00089 19.0 0.0 0.1 12.3 0.0 2.6 2 1 0 2 2 2 1 Right handed beta helix region EcKinase PF02958.15 CAM71736.1 - 0.024 13.8 0.0 0.036 13.2 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase NosD PF05048.8 CAM71736.1 - 0.22 10.6 0.0 0.53 9.3 0.0 1.5 2 0 0 2 2 2 0 Periplasmic copper-binding protein (NosD) Cyt-b5 PF00173.23 CAM71737.1 - 1.3e-07 31.3 0.1 1.8e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Mito_carr PF00153.22 CAM71738.1 - 1.9e-47 158.9 4.7 3.5e-22 77.9 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Neurensin PF14927.1 CAM71738.1 - 0.0089 15.4 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Neurensin SWIM PF04434.12 CAM71739.1 - 1.4 8.4 5.2 0.87 9.1 0.7 2.4 2 0 0 2 2 2 0 SWIM zinc finger DNA_pol_A_exo1 PF01612.15 CAM71740.1 - 1e-39 135.8 0.5 1.7e-39 135.1 0.3 1.4 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 CAM71740.1 - 8.7e-23 80.4 0.0 7.9e-22 77.3 0.0 2.4 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.18 CAM71740.1 - 2.7e-09 36.6 0.0 5.7e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 HRDC domain PIP5K PF01504.13 CAM71741.1 - 8e-70 234.8 0.0 1.3e-69 234.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase AAA_33 PF13671.1 CAM71743.1 - 5.8e-16 58.6 0.0 1.2e-15 57.6 0.0 1.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CAM71743.1 - 0.00018 20.6 0.0 0.00039 19.5 0.0 1.5 1 1 0 1 1 1 1 Zeta toxin KTI12 PF08433.5 CAM71743.1 - 0.0008 18.6 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_5 PF07728.9 CAM71743.1 - 0.0048 16.6 0.0 0.0073 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CAM71743.1 - 0.0049 17.6 0.0 0.0072 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CAM71743.1 - 0.01 16.0 0.1 0.028 14.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CAM71743.1 - 0.015 15.2 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Ctr PF04145.10 CAM71743.1 - 0.034 14.1 0.0 0.055 13.5 0.0 1.4 1 0 0 1 1 1 0 Ctr copper transporter family Arch_ATPase PF01637.13 CAM71743.1 - 0.079 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase TPT PF03151.11 CAM71744.1 - 9.5e-06 25.3 14.3 9.5e-06 25.3 9.9 2.8 1 1 1 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 CAM71744.1 - 0.0013 17.7 27.2 0.0025 16.8 18.9 1.4 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 CAM71744.1 - 1.3 9.0 35.1 1.1 9.3 10.4 2.4 2 1 0 2 2 2 0 EamA-like transporter family E1-E2_ATPase PF00122.15 CAM71745.1 - 2.4e-20 72.5 0.0 5.3e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CAM71745.1 - 9.9e-12 45.7 0.0 7.2e-08 33.1 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 CAM71745.1 - 5.9e-10 39.6 0.1 1.4e-09 38.4 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CAM71745.1 - 2.5e-08 33.7 0.0 7.9e-08 32.1 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CAM71745.1 - 0.0017 18.0 0.2 0.0028 17.2 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HA2 PF04408.18 CAM71746.1 - 2.7e-15 56.2 0.0 9.2e-15 54.5 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) dsrm PF00035.20 CAM71746.1 - 1.1e-10 41.9 0.1 0.00056 20.4 0.0 4.9 4 0 0 4 4 4 2 Double-stranded RNA binding motif Helicase_C PF00271.26 CAM71746.1 - 2.2e-09 37.0 0.0 7.6e-09 35.3 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAM71746.1 - 4.2e-07 29.6 0.1 9.4e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CAM71746.1 - 1e-05 25.6 0.1 7.6e-05 22.8 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 CAM71746.1 - 0.019 14.8 0.3 0.25 11.2 0.2 2.4 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 CAM71746.1 - 0.056 12.5 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.1 CAM71746.1 - 0.17 12.2 0.0 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CAM71746.1 - 0.91 9.1 0.0 1.7 8.2 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase TPP_enzyme_N PF02776.13 CAM71748.1 - 4.6e-35 120.6 0.1 8.3e-35 119.7 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 CAM71748.1 - 2.3e-20 72.7 0.0 5.8e-20 71.4 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 CAM71748.1 - 3.1e-17 62.6 0.1 7e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DXP_synthase_N PF13292.1 CAM71748.1 - 0.13 11.1 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase DRMBL PF07522.9 CAM71749.2 - 7.2e-18 64.6 0.0 1.7e-17 63.4 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 CAM71749.2 - 2.8e-06 27.0 0.0 2.3e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CAM71749.2 - 1.6 8.3 5.9 42 3.7 4.1 2.4 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily DUF4379 PF14311.1 CAM71750.1 - 4.2e-15 55.2 0.2 7.4e-15 54.5 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4379) zf-UBP PF02148.14 CAM71751.1 - 1.4e-15 57.1 8.2 1.4e-15 57.1 5.7 2.4 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UPF0054 PF02130.12 CAM71753.1 - 7.7e-40 135.5 0.0 9e-40 135.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 LRR_6 PF13516.1 CAM71754.1 - 1.4e-05 24.7 6.9 3.4 8.0 0.4 4.6 4 0 0 4 4 4 3 Leucine Rich repeat LRR_4 PF12799.2 CAM71754.1 - 1.4e-05 24.5 2.8 0.013 15.0 0.2 3.3 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CAM71754.1 - 0.0092 15.8 7.0 14 6.2 0.1 4.6 4 0 0 4 4 4 2 Leucine Rich Repeat Sensor_TM1 PF13755.1 CAM71754.1 - 0.08 12.4 0.4 0.49 9.9 0.0 2.2 2 0 0 2 2 2 0 Sensor N-terminal transmembrane domain LRR_7 PF13504.1 CAM71754.1 - 0.61 10.5 6.0 33 5.3 0.2 4.5 4 0 0 4 4 4 0 Leucine rich repeat OrfB_IS605 PF01385.14 CAM71755.1 - 0.036 13.4 0.6 0.041 13.2 0.4 1.2 1 0 0 1 1 1 0 Probable transposase p450 PF00067.17 CAM71756.1 - 8.1e-60 202.6 0.0 1.2e-59 202.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1477 PF07346.6 CAM71756.1 - 0.00061 19.8 0.4 0.0012 18.8 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1477) AAA PF00004.24 CAM71758.1 - 7.3e-35 120.0 0.0 2.2e-34 118.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CAM71758.1 - 2e-05 24.7 0.3 0.012 15.8 0.0 3.4 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CAM71758.1 - 2.3e-05 24.1 0.0 0.0001 22.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CAM71758.1 - 2.4e-05 24.0 0.5 0.00019 21.1 0.0 2.9 3 0 0 3 3 3 1 Part of AAA domain AAA_17 PF13207.1 CAM71758.1 - 0.00012 22.8 0.0 0.00045 21.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CAM71758.1 - 0.00036 19.6 0.0 0.0017 17.4 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 CAM71758.1 - 0.00048 19.8 0.1 0.34 10.5 0.0 2.8 2 1 1 3 3 3 2 NACHT domain AAA_16 PF13191.1 CAM71758.1 - 0.0007 19.6 2.0 0.021 14.8 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.12 CAM71758.1 - 0.0039 16.6 0.0 0.0089 15.4 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 CAM71758.1 - 0.0045 16.8 0.0 0.019 14.8 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CAM71758.1 - 0.0052 16.6 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 CAM71758.1 - 0.012 14.3 0.0 0.079 11.6 0.0 2.1 2 0 0 2 2 2 0 TIP49 C-terminus AAA_25 PF13481.1 CAM71758.1 - 0.023 14.0 0.0 0.048 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 CAM71758.1 - 0.028 14.2 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Mg_chelatase PF01078.16 CAM71758.1 - 0.046 12.8 0.1 0.17 11.0 0.0 2.1 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 CAM71758.1 - 0.048 13.2 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 CAM71758.1 - 0.1 12.5 0.0 0.26 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 CAM71758.1 - 0.12 12.5 0.0 0.81 9.8 0.0 2.2 2 0 0 2 2 2 0 RNA helicase Tyr_Deacylase PF02580.11 CAM71759.1 - 2.5e-43 147.5 0.0 2.9e-43 147.3 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase S4 PF01479.20 CAM71759.1 - 0.13 11.7 0.1 0.3 10.5 0.0 1.6 1 0 0 1 1 1 0 S4 domain Aldose_epim PF01263.15 CAM71761.1 - 3.3e-31 108.5 0.0 4.6e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase DUF2389 PF09493.5 CAM71761.1 - 0.014 15.6 0.0 2.1 8.6 0.0 2.5 2 0 0 2 2 2 0 Tryptophan-rich protein (DUF2389) HECT PF00632.20 CAM71762.1 - 9e-08 31.6 0.0 0.023 13.8 0.0 3.0 3 0 0 3 3 3 2 HECT-domain (ubiquitin-transferase) DCP2 PF05026.8 CAM71762.1 - 0.05 13.5 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 Dcp2, box A domain HECT PF00632.20 CAM71763.1 - 3.9e-07 29.5 0.0 1.7e-06 27.4 0.1 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DUF3153 PF11353.3 CAM71764.1 - 0.13 11.6 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) Lactamase_B PF00753.22 CAM71765.1 - 6.9e-15 55.2 0.1 1.6e-14 53.9 0.0 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CAM71765.1 - 0.036 13.6 0.0 0.067 12.7 0.0 1.5 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Beta-Casp PF10996.3 CAM71766.1 - 2.9e-32 111.2 0.0 7.3e-32 109.9 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 CAM71766.1 - 1.3e-19 70.6 0.1 2.2e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily CPSF73-100_C PF11718.3 CAM71766.1 - 3.7e-11 42.7 0.0 6.6e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Lactamase_B_2 PF12706.2 CAM71766.1 - 4.6e-10 39.3 0.0 1.1e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 CAM71766.1 - 1.4e-08 34.4 0.0 3.7e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 CAM71766.1 - 0.0001 22.0 0.0 0.00028 20.6 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Topoisom_I_N PF02919.10 CAM71767.1 - 8.8e-95 316.0 1.2 8.8e-95 316.0 0.9 3.2 2 1 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 CAM71767.1 - 8.3e-84 280.3 0.5 8.3e-84 280.3 0.4 1.8 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core LRR_9 PF14580.1 CAM71768.1 - 0.00011 21.8 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 CAM71768.1 - 0.00044 19.8 0.2 0.015 14.9 0.0 2.6 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM71768.1 - 0.0064 16.2 0.4 0.0064 16.2 0.3 2.0 2 0 0 2 2 2 1 Leucine rich repeat zf-RanBP PF00641.13 CAM71769.1 - 2.1e-05 23.5 2.6 2.1e-05 23.5 1.8 1.7 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others zf-CCCH PF00642.19 CAM71769.1 - 0.069 12.8 1.4 0.19 11.4 1.0 1.7 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF35_N PF12172.3 CAM71769.1 - 0.092 12.6 3.3 0.35 10.8 2.3 2.1 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Amidinotransf PF02274.12 CAM71770.1 - 6.8e-12 45.0 0.0 1e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Amidinotransferase DUF422 PF04240.7 CAM71770.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF422) LRR_6 PF13516.1 CAM71771.1 - 0.01 15.8 1.4 0.08 13.0 0.0 2.7 2 0 0 2 2 2 0 Leucine Rich repeat LRR_4 PF12799.2 CAM71771.1 - 0.11 12.1 0.6 0.38 10.4 0.4 1.9 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) TPR_12 PF13424.1 CAM71772.1 - 6.6e-38 128.5 37.6 9.9e-13 47.8 0.2 5.4 2 2 3 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.1 CAM71772.1 - 9e-23 79.4 25.5 1e-06 28.4 0.0 7.3 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.1 CAM71772.1 - 1.3e-12 47.1 22.0 6.8e-07 28.8 0.0 5.7 2 2 5 7 7 7 5 TPR repeat TPR_8 PF13181.1 CAM71772.1 - 2.1e-10 39.6 17.9 0.00037 20.0 0.1 7.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 CAM71772.1 - 1.8e-06 28.0 24.1 0.76 10.5 0.0 7.8 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 CAM71772.1 - 0.00037 21.0 25.1 0.35 11.6 0.1 6.1 3 2 3 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 CAM71772.1 - 0.0015 18.2 15.9 0.83 9.6 0.0 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat Drf_FH3 PF06367.11 CAM71772.1 - 0.0037 16.6 0.0 0.0072 15.7 0.0 1.4 1 0 0 1 1 1 1 Diaphanous FH3 Domain B12-binding_2 PF02607.12 CAM71772.1 - 0.05 13.6 0.0 2.9 7.9 0.0 2.8 2 0 0 2 2 2 0 B12 binding domain ATG16 PF08614.6 CAM71772.1 - 0.079 12.7 2.7 2 8.1 0.2 2.6 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) TPR_19 PF14559.1 CAM71772.1 - 0.095 13.0 12.8 1.5 9.2 1.2 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 CAM71772.1 - 0.099 12.2 17.5 13 5.5 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat Rapsyn_N PF10579.4 CAM71772.1 - 0.11 12.3 1.8 19 5.1 0.0 3.6 2 1 2 4 4 3 0 Rapsyn N-terminal myristoylation and linker region Tcf25 PF04910.9 CAM71772.1 - 0.28 10.0 1.9 2 7.2 0.1 2.5 3 0 0 3 3 3 0 Transcriptional repressor TCF25 DUF3301 PF11743.3 CAM71772.1 - 0.56 9.7 3.8 9 5.9 0.0 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3301) TPR_2 PF07719.12 CAM71772.1 - 1.7 8.7 29.2 0.19 11.6 0.3 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat TIP49 PF06068.8 CAM71773.1 - 1.5e-183 610.0 2.1 1.8e-183 609.8 1.5 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 CAM71773.1 - 4.8e-13 48.7 1.2 9.8e-08 31.3 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 CAM71773.1 - 8e-12 45.4 0.8 4e-07 30.3 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CAM71773.1 - 7.5e-07 29.3 0.1 0.037 14.1 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CAM71773.1 - 6.5e-06 26.2 0.0 0.00062 19.8 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.16 CAM71773.1 - 0.00011 21.4 0.2 0.0069 15.5 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CAM71773.1 - 0.00032 20.4 0.1 0.093 12.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CAM71773.1 - 0.0011 18.6 0.5 0.0039 16.9 0.2 2.1 1 1 1 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 CAM71773.1 - 0.0012 18.3 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CAM71773.1 - 0.0028 17.5 0.0 0.018 14.9 0.0 2.3 4 0 0 4 4 3 1 AAA domain IstB_IS21 PF01695.12 CAM71773.1 - 0.0047 16.3 0.4 0.028 13.8 0.1 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.1 CAM71773.1 - 0.0067 17.2 0.0 0.026 15.3 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_32 PF13654.1 CAM71773.1 - 0.0075 14.9 0.7 0.49 8.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.1 CAM71773.1 - 0.01 15.7 0.0 0.027 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CAM71773.1 - 0.011 15.6 0.0 2.8 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 CAM71773.1 - 0.012 15.8 0.1 0.11 12.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain MinE PF03776.9 CAM71773.1 - 0.028 13.8 0.2 0.071 12.6 0.1 1.6 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE AAA_11 PF13086.1 CAM71773.1 - 0.041 13.4 0.1 0.1 12.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain DnaB_C PF03796.10 CAM71773.1 - 0.064 12.1 0.0 0.14 11.0 0.0 1.6 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Sigma54_activat PF00158.21 CAM71773.1 - 0.07 12.6 0.1 9.8 5.6 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain ResIII PF04851.10 CAM71773.1 - 0.093 12.5 0.3 2.2 8.0 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit SET PF00856.23 CAM71774.1 - 0.017 15.4 0.0 0.026 14.8 0.0 1.4 1 1 0 1 1 1 0 SET domain AAA PF00004.24 CAM71775.1 - 1.6e-49 167.4 0.0 1.3e-37 128.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 CAM71775.1 - 3.9e-21 74.8 0.2 8.9e-21 73.7 0.1 1.7 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 CAM71775.1 - 9.5e-12 45.2 5.5 2.5e-05 24.3 0.1 4.6 3 3 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 CAM71775.1 - 4.1e-09 36.6 0.2 0.013 15.6 0.0 3.9 4 1 1 5 5 3 2 AAA domain DUF815 PF05673.8 CAM71775.1 - 1.3e-07 30.8 0.0 0.00018 20.5 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF815) AAA_33 PF13671.1 CAM71775.1 - 1.5e-06 28.1 0.0 0.011 15.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 CAM71775.1 - 2.1e-06 27.6 0.0 0.0025 17.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CAM71775.1 - 2.5e-05 24.0 0.1 0.047 13.4 0.0 3.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.1 CAM71775.1 - 2.6e-05 24.2 0.0 0.0094 16.0 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.1 CAM71775.1 - 2.9e-05 24.0 0.0 0.027 14.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 CAM71775.1 - 3.2e-05 23.5 0.0 0.046 13.2 0.0 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.1 CAM71775.1 - 4.2e-05 24.3 0.1 0.0057 17.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CAM71775.1 - 5.7e-05 22.5 0.0 0.062 12.8 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain RNA_helicase PF00910.17 CAM71775.1 - 7.2e-05 22.9 0.0 0.031 14.4 0.0 2.6 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.12 CAM71775.1 - 0.00011 21.6 0.0 0.09 12.1 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein ABC_tran PF00005.22 CAM71775.1 - 0.00012 22.4 0.0 0.53 10.5 0.0 2.9 3 0 0 3 3 2 2 ABC transporter AAA_2 PF07724.9 CAM71775.1 - 0.00017 21.5 0.0 0.00066 19.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF258 PF03193.11 CAM71775.1 - 0.00025 20.2 0.0 0.62 9.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 CAM71775.1 - 0.00048 19.5 4.5 6.4 6.1 0.0 5.3 4 1 2 6 6 6 0 AAA domain Arch_ATPase PF01637.13 CAM71775.1 - 0.00066 19.4 0.0 0.52 9.9 0.0 3.1 2 1 1 3 3 3 1 Archaeal ATPase Vps4_C PF09336.5 CAM71775.1 - 0.00074 19.3 0.0 0.002 17.9 0.0 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain T2SE PF00437.15 CAM71775.1 - 0.00084 18.3 0.0 0.54 9.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein NACHT PF05729.7 CAM71775.1 - 0.001 18.7 1.0 2.9 7.5 0.0 4.3 3 1 0 4 4 4 1 NACHT domain Zeta_toxin PF06414.7 CAM71775.1 - 0.0017 17.5 0.0 1.4 8.0 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin FtsK_SpoIIIE PF01580.13 CAM71775.1 - 0.0019 17.7 0.2 0.032 13.6 0.0 2.8 3 0 0 3 3 3 1 FtsK/SpoIIIE family Mg_chelatase PF01078.16 CAM71775.1 - 0.0028 16.8 0.0 1.5 7.9 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CAM71775.1 - 0.0028 17.1 0.1 2.9 7.3 0.0 2.9 3 0 0 3 3 2 1 Sigma-54 interaction domain Rad17 PF03215.10 CAM71775.1 - 0.0053 15.5 0.0 0.63 8.6 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Miro PF08477.8 CAM71775.1 - 0.018 15.4 0.0 2.8 8.4 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein AAA_23 PF13476.1 CAM71775.1 - 0.033 14.5 0.1 10 6.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 CAM71775.1 - 0.09 11.3 0.0 0.71 8.4 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NTPase_1 PF03266.10 CAM71775.1 - 0.093 12.4 0.2 2.6 7.7 0.1 2.6 2 0 0 2 2 2 0 NTPase AAA_10 PF12846.2 CAM71775.1 - 0.096 12.1 0.0 12 5.2 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain MobB PF03205.9 CAM71775.1 - 0.14 11.8 0.6 4.4 6.9 0.2 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 CAM71775.1 - 0.14 11.6 0.1 2.5 7.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 CAM71775.1 - 0.16 12.3 0.0 3 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.13 CAM71775.1 - 0.19 11.3 0.0 15 5.1 0.0 2.9 3 0 0 3 3 3 0 Bacterial dnaA protein RHD3 PF05879.7 CAM71776.1 - 0.11 10.3 0.0 0.17 9.8 0.0 1.1 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) LicD PF04991.8 CAM71777.1 - 3.7e-14 53.3 0.0 1.2e-06 28.7 0.0 2.1 1 1 1 2 2 2 2 LicD family Deltaretro_Tax PF05599.6 CAM71777.1 - 0.009 16.2 0.0 0.023 15.0 0.0 1.7 1 0 0 1 1 1 1 Deltaretrovirus Tax protein PDCD2_C PF04194.8 CAM71778.1 - 1.3e-22 80.1 0.0 2.9e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain Elf1 PF05129.8 CAM71778.1 - 0.0095 15.6 0.5 0.095 12.4 0.1 2.2 2 0 0 2 2 2 1 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.1 CAM71778.1 - 0.065 13.5 1.9 2 8.7 0.1 2.7 2 0 0 2 2 2 0 Restriction alleviation protein Lar DUF3268 PF11672.3 CAM71778.1 - 1.6 8.8 4.9 0.29 11.2 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3268) Ank_2 PF12796.2 CAM71779.1 - 1.1e-34 118.6 3.0 1.7e-17 63.5 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CAM71779.1 - 7.1e-33 110.7 1.5 2.1e-09 36.7 0.1 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 CAM71779.1 - 9.9e-25 86.4 0.7 2.8e-06 27.6 0.1 5.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CAM71779.1 - 1.4e-23 80.6 1.0 1.9e-06 27.5 0.1 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 CAM71779.1 - 8.1e-23 79.9 4.7 1.9e-08 34.2 0.2 4.6 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Methyltransf_26 PF13659.1 CAM71781.1 - 0.056 13.4 0.2 0.41 10.6 0.0 2.6 3 1 0 3 3 3 0 Methyltransferase domain PI3_PI4_kinase PF00454.22 CAM71782.1 - 4.3e-36 124.5 0.1 1.8e-34 119.2 0.0 2.6 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PfkB PF00294.19 CAM71783.1 - 1.2e-40 139.5 0.2 9.9e-40 136.5 0.1 1.9 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Complex1_LYR PF05347.10 CAM71784.1 - 1.1e-11 44.3 0.6 1.8e-11 43.6 0.5 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CAM71784.1 - 2.3e-09 37.3 0.5 3.6e-09 36.6 0.4 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Herpes_UL14 PF03580.9 CAM71784.1 - 0.046 13.5 0.3 0.68 9.7 0.0 2.0 1 1 1 2 2 2 0 Herpesvirus UL14-like protein DUF3336 PF11815.3 CAM71785.1 - 4.6e-25 87.8 0.0 8.2e-25 87.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 CAM71785.1 - 3.3e-11 43.5 0.2 6.4e-11 42.5 0.1 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase Metallophos_2 PF12850.2 CAM71786.1 - 9.2e-06 25.5 0.0 0.00013 21.7 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 CAM71786.1 - 0.00057 19.3 0.0 0.095 12.0 0.0 2.5 3 0 0 3 3 3 2 Calcineurin-like phosphoesterase DUF2975 PF11188.3 CAM71787.1 - 0.0038 16.9 0.5 0.0053 16.4 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2975) HemY_N PF07219.8 CAM71787.1 - 8.5 5.9 11.7 3.4 7.2 0.3 3.2 2 1 1 3 3 3 0 HemY protein N-terminus DUF2975 PF11188.3 CAM71788.1 - 0.039 13.6 0.3 0.055 13.1 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) DUF4401 PF14351.1 CAM71788.1 - 0.04 12.9 2.7 0.1 11.5 1.8 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4401) CopD PF05425.8 CAM71788.1 - 0.093 12.9 2.7 0.14 12.4 1.9 1.2 1 0 0 1 1 1 0 Copper resistance protein D Ribosomal_L21e PF01157.13 CAM71789.1 - 3.2e-35 119.8 2.5 4.6e-35 119.3 1.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e EMP70 PF02990.11 CAM71790.1 - 1.1e-113 380.4 0.5 1.5e-113 380.0 0.4 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 ATP-synt_ab PF00006.20 CAM71791.1 - 2.1e-108 360.8 0.0 3.2e-108 360.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CAM71791.1 - 1.9e-24 86.2 0.2 3.2e-24 85.5 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CAM71791.1 - 2.3e-15 56.5 1.3 2.3e-15 56.5 0.9 2.6 3 0 0 3 3 3 1 ATP synthase alpha/beta family, beta-barrel domain DUF2737 PF10930.3 CAM71791.1 - 0.08 12.5 0.1 12 5.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2737) AAA_31 PF13614.1 CAM71791.1 - 0.14 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ribosomal_L13 PF00572.13 CAM71792.1 - 1.2e-30 106.2 0.0 1.5e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Ins_P5_2-kin PF06090.7 CAM71794.1 - 7.9e-19 67.8 0.0 1.2e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DUF4347 PF14252.1 CAM71794.1 - 0.093 12.2 0.1 0.29 10.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4347) Acyl-thio_N PF12590.3 CAM71795.1 - 0.47 10.9 3.2 0.29 11.6 0.8 1.6 1 1 1 2 2 2 0 Acyl-ATP thioesterase DUF501 PF04417.7 CAM71796.1 - 6.1e-34 116.8 0.2 1.1e-33 116.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF501) Aminotran_1_2 PF00155.16 CAM71798.1 - 1.1e-44 152.9 0.0 1.3e-44 152.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CAM71798.1 - 0.016 14.3 0.0 0.034 13.2 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase DUF1227 PF06777.6 CAM71798.1 - 0.07 12.8 0.0 1.3 8.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1227) LIM PF00412.17 CAM71800.1 - 0.018 15.0 8.6 0.053 13.5 5.2 2.2 2 0 0 2 2 2 0 LIM domain zf-UDP PF14569.1 CAM71800.1 - 0.31 10.8 4.6 1.3 8.8 3.2 2.0 1 0 0 1 1 1 0 Zinc-binding RING-finger zinc_ribbon_6 PF14599.1 CAM71800.1 - 1.1 9.1 5.5 2.5 7.9 3.8 1.6 1 0 0 1 1 1 0 Zinc-ribbon Actin PF00022.14 CAM71801.1 - 2.9e-32 111.5 0.0 3.6e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Actin TetR_C_6 PF13977.1 CAM71801.1 - 0.016 15.1 0.1 4.1 7.4 0.0 2.7 2 1 0 2 2 2 0 Bacterial transcriptional repressor Ribosomal_60s PF00428.14 CAM71802.1 - 0.059 13.7 1.1 0.13 12.6 0.8 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein PGM_PMM_I PF02878.11 CAM71803.1 - 1.4e-37 128.2 0.1 3e-37 127.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 CAM71803.1 - 4e-20 72.0 0.0 1.4e-19 70.3 0.0 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 CAM71803.1 - 1.1e-13 51.1 0.1 4.6e-13 49.2 0.1 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 CAM71803.1 - 1.2e-05 25.2 0.0 4.3e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain WD40 PF00400.27 CAM71804.1 - 0.029 14.2 0.2 1.2 9.1 0.0 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat PQQ_3 PF13570.1 CAM71804.1 - 3.6 7.9 7.4 3.1 8.1 0.6 3.8 3 1 0 3 3 3 0 PQQ-like domain DUF164 PF02591.10 CAM71806.1 - 0.0043 16.8 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 Putative zinc ribbon domain Ribosomal_L14 PF00238.14 CAM71807.1 - 2.3e-12 46.7 0.0 4.1e-12 45.9 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L14p/L23e TPR_11 PF13414.1 CAM71808.1 - 4.4e-14 51.8 4.8 4.3e-07 29.4 2.2 3.2 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 CAM71808.1 - 1.5e-07 30.7 8.1 0.073 12.7 0.0 3.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 CAM71808.1 - 6.6e-07 28.7 10.2 0.077 12.9 0.1 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 CAM71808.1 - 3.4e-06 26.9 3.1 0.085 12.8 0.7 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CAM71808.1 - 0.0049 17.5 3.0 3.6 8.3 0.1 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 CAM71808.1 - 0.0056 16.9 0.0 1.3 9.4 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 CAM71808.1 - 0.014 15.5 0.2 11 6.4 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 CAM71808.1 - 0.017 14.8 0.0 0.57 10.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 CAM71808.1 - 0.019 15.0 4.8 0.32 11.1 2.6 2.8 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CAM71808.1 - 0.023 14.5 0.5 6.4 6.7 0.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 CAM71808.1 - 0.084 12.8 0.5 18 5.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 CAM71808.1 - 0.11 12.3 7.2 9.6 6.2 0.0 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 CAM71808.1 - 0.13 12.9 0.6 48 4.9 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CAM71808.1 - 0.35 11.4 5.7 18 6.0 1.3 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat Toxin_36 PF10550.4 CAM71808.1 - 0.89 10.8 4.1 6.3 8.2 0.7 2.7 2 0 0 2 2 2 0 Conantokin-G mollusc-toxin Atg14 PF10186.4 CAM71809.1 - 7.3e-05 21.8 6.8 7.3e-05 21.8 4.7 1.9 2 0 0 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 DUF745 PF05335.8 CAM71809.1 - 0.00079 19.0 7.1 0.00079 19.0 4.9 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF745) DUF955 PF06114.8 CAM71809.1 - 0.035 13.8 1.5 0.056 13.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF955) Borrelia_P83 PF05262.6 CAM71809.1 - 0.09 11.0 5.4 0.1 10.8 3.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein MscS_porin PF12795.2 CAM71809.1 - 0.11 11.7 17.3 0.048 12.9 9.4 2.1 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain DUF45 PF01863.12 CAM71809.1 - 0.17 11.6 6.9 6 6.6 3.6 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF45 Nup88 PF10168.4 CAM71809.1 - 0.43 8.3 5.4 0.59 7.9 3.8 1.1 1 0 0 1 1 1 0 Nuclear pore component V_ATPase_I PF01496.14 CAM71809.1 - 0.64 7.8 4.0 0.16 9.7 1.0 1.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Acyl-CoA_dh_2 PF08028.6 CAM71809.1 - 1.1 9.5 17.7 0.18 12.0 8.0 2.1 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain IncA PF04156.9 CAM71809.1 - 1.7 8.2 17.5 5 6.6 11.5 2.0 2 1 0 2 2 2 0 IncA protein AAA_16 PF13191.1 CAM71809.1 - 2.8 7.9 10.7 1 9.2 4.7 1.9 2 0 0 2 2 2 0 AAA ATPase domain DUF972 PF06156.8 CAM71809.1 - 3.3 8.1 5.7 6.9 7.0 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Selenoprotein_S PF06936.6 CAM71809.1 - 5.3 6.5 12.5 0.45 10.0 4.8 2.0 2 1 0 2 2 2 0 Selenoprotein S (SelS) Spc7 PF08317.6 CAM71809.1 - 6.7 5.2 9.0 2.2 6.8 3.7 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein DivIVA PF05103.8 CAM71809.1 - 7.5 6.6 13.3 1.7 8.7 5.0 2.2 2 0 0 2 2 2 0 DivIVA protein F-box-like PF12937.2 CAM71810.1 - 0.37 10.5 2.5 1.4 8.7 0.0 2.7 3 0 0 3 3 3 0 F-box-like MIP PF00230.15 CAM71811.1 - 5.7e-35 120.8 18.8 3.5e-34 118.2 13.0 1.9 1 1 0 1 1 1 1 Major intrinsic protein ABC2_membrane_4 PF12730.2 CAM71811.1 - 0.058 12.5 24.2 0.012 14.7 1.8 3.1 2 1 1 3 3 3 0 ABC-2 family transporter protein DUF389 PF04087.9 CAM71811.1 - 0.14 12.1 10.0 0.015 15.2 3.2 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF389) LSM PF01423.17 CAM71812.1 - 2.8e-12 45.9 0.2 3.8e-12 45.5 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CAM71812.1 - 0.0095 15.8 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain DnaJ PF00226.26 CAM71813.1 - 1.8e-19 69.2 0.0 3.1e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain TPR_11 PF13414.1 CAM71813.1 - 0.0072 15.9 2.6 0.39 10.4 0.2 3.6 1 1 2 3 3 3 2 TPR repeat TPR_14 PF13428.1 CAM71813.1 - 0.31 11.7 7.6 19 6.2 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 CAM71813.1 - 0.32 10.8 5.4 4.7 7.1 0.6 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 CAM71813.1 - 0.62 10.8 15.1 4.6 8.0 0.7 5.3 4 1 1 5 5 5 0 Tetratricopeptide repeat Dynein_heavy PF03028.10 CAM71814.2 - 2.9e-218 726.4 0.0 2.9e-218 726.4 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor DHC_N1 PF08385.7 CAM71814.2 - 7.8e-129 430.6 0.2 7.8e-129 430.6 0.1 2.9 3 0 0 3 3 2 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 CAM71814.2 - 6.5e-123 410.2 3.4 6.5e-123 410.2 2.3 4.8 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CAM71814.2 - 2.9e-101 337.8 0.0 7.1e-101 336.5 0.0 1.7 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 CAM71814.2 - 1.4e-71 240.5 0.0 2.5e-71 239.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.2 CAM71814.2 - 1.5e-53 181.6 0.1 1.3e-52 178.6 0.0 2.5 2 1 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_9 PF12781.2 CAM71814.2 - 5.8e-47 159.4 0.2 1.5e-46 158.1 0.0 1.8 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 MT PF12777.2 CAM71814.2 - 1.1e-41 142.7 8.4 1.8e-41 142.0 5.8 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 CAM71814.2 - 2.4e-23 82.4 0.5 3.8e-07 29.9 0.0 7.7 6 2 0 6 6 6 4 AAA domain (dynein-related subfamily) AAA PF00004.24 CAM71814.2 - 5.1e-09 36.4 1.7 0.64 10.2 0.0 6.3 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CAM71814.2 - 5.5e-08 33.0 6.8 0.1 12.5 0.0 6.7 6 1 1 7 7 5 2 AAA ATPase domain AAA_22 PF13401.1 CAM71814.2 - 3.7e-06 27.1 3.7 0.93 9.6 0.0 6.3 6 0 0 6 6 5 1 AAA domain DUF258 PF03193.11 CAM71814.2 - 0.00016 20.8 0.7 0.023 13.8 0.1 3.5 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 CAM71814.2 - 0.0005 20.8 0.0 9.7 7.0 0.0 5.0 4 0 0 4 4 4 0 AAA domain AAA_33 PF13671.1 CAM71814.2 - 0.00085 19.2 3.3 0.44 10.4 0.0 4.8 5 0 0 5 5 4 1 AAA domain AAA_29 PF13555.1 CAM71814.2 - 0.0039 16.7 0.7 0.073 12.6 0.0 2.8 3 0 0 3 3 2 1 P-loop containing region of AAA domain RNA_helicase PF00910.17 CAM71814.2 - 0.029 14.5 2.0 2.3 8.4 0.0 3.4 3 0 0 3 3 3 0 RNA helicase ABC_tran PF00005.22 CAM71814.2 - 0.029 14.6 3.3 1.1 9.5 0.0 4.3 4 0 0 4 4 4 0 ABC transporter SMC_N PF02463.14 CAM71814.2 - 0.16 11.1 0.1 1.8 7.7 0.0 2.6 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain MobB PF03205.9 CAM71814.2 - 0.2 11.3 3.4 0.93 9.1 0.1 3.1 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Carla_C4 PF01623.12 CAM71814.2 - 0.59 9.9 2.0 2.6 7.8 0.1 2.5 2 0 0 2 2 2 0 Carlavirus putative nucleic acid binding protein AAA_18 PF13238.1 CAM71814.2 - 0.63 10.3 6.3 8.9 6.6 0.0 4.5 4 0 0 4 4 3 0 AAA domain DUF1512 PF07431.7 CAM71815.1 - 0.015 14.0 0.0 0.027 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) HATPase_c PF02518.21 CAM71816.1 - 8e-15 54.5 0.0 1.6e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CAM71816.1 - 0.00034 20.2 0.0 0.00058 19.5 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 CAM71816.1 - 0.11 12.3 0.0 0.32 10.8 0.0 1.8 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Pet191_N PF10203.4 CAM71817.1 - 3.4e-17 62.2 3.4 4.6e-17 61.8 2.3 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 AFP PF02420.10 CAM71817.1 - 0.92 9.8 2.9 20 5.7 0.2 2.5 2 0 0 2 2 2 0 Insect antifreeze protein repeat NIF PF03031.13 CAM71818.1 - 1.2e-27 96.5 0.0 1.9e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF705 PF05152.7 CAM71818.1 - 0.00022 20.3 0.0 0.00033 19.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF705) HAD_2 PF13419.1 CAM71818.1 - 0.025 14.7 0.0 0.17 12.0 0.0 2.1 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase LBP_BPI_CETP_C PF02886.12 CAM71819.1 - 0.0019 17.4 0.4 0.029 13.6 0.0 2.6 3 0 0 3 3 3 1 LBP / BPI / CETP family, C-terminal domain PI3_PI4_kinase PF00454.22 CAM71820.1 - 3e-50 170.8 0.2 6.6e-50 169.7 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 CAM71820.1 - 4.4e-23 81.8 0.4 1.4e-22 80.2 0.1 2.0 2 1 0 2 2 2 1 FAT domain Rapamycin_bind PF08771.6 CAM71820.1 - 2.3e-20 72.5 0.3 1.1e-19 70.4 0.2 2.3 1 0 0 1 1 1 1 Rapamycin binding domain DUF3385 PF11865.3 CAM71820.1 - 7.7e-14 51.9 1.1 5.4e-13 49.1 0.2 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) FATC PF02260.15 CAM71820.1 - 2.9e-13 49.0 1.6 9.5e-13 47.3 0.0 2.6 3 0 0 3 3 3 1 FATC domain PDZ PF00595.19 CAM71820.1 - 0.00015 21.9 0.1 0.00037 20.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CAM71820.1 - 0.18 11.6 0.0 0.47 10.3 0.0 1.6 1 0 0 1 1 1 0 PDZ domain Fmp27_WPPW PF10359.4 CAM71821.1 - 0.022 13.1 0.0 0.028 12.8 0.0 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain UPF0184 PF03670.8 CAM71821.1 - 0.046 13.9 0.1 0.089 12.9 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) SHIPPO-rpt PF07004.7 CAM71821.1 - 0.24 12.3 1.9 0.67 10.9 1.3 1.8 1 0 0 1 1 1 0 Sperm-tail PG-rich repeat Herpes_capsid PF06112.6 CAM71821.1 - 2.5 8.1 6.0 0.62 10.1 1.3 1.9 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein PIG-Y PF15159.1 CAM71822.1 - 0.066 13.4 2.1 0.088 13.0 1.5 1.2 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y PIG-Y PF15159.1 CAM71823.1 - 2.1e-05 24.6 1.1 3.5e-05 23.9 0.8 1.4 1 1 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Permease PF02405.11 CAM71823.1 - 0.021 14.3 0.0 0.024 14.1 0.0 1.1 1 0 0 1 1 1 0 Permease HECT PF00632.20 CAM71824.2 - 4.7e-53 180.3 0.0 9.7e-53 179.3 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Adaptin_N PF01602.15 CAM71825.1 - 1.3e-72 244.8 5.0 1.7e-72 244.4 3.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 CAM71825.1 - 5.4e-10 39.5 0.0 1.2e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Ribosomal_L7Ae PF01248.21 CAM71826.1 - 2.2e-19 68.7 0.3 2.7e-19 68.4 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Rgp1 PF08737.5 CAM71827.1 - 1.1e-10 41.1 0.1 1e-06 28.1 0.0 2.4 3 0 0 3 3 3 2 Rgp1 Arrestin_N PF00339.24 CAM71827.1 - 0.081 12.7 0.3 0.3 10.9 0.0 2.0 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Peptidase_C78 PF07910.8 CAM71828.1 - 8.1e-50 168.9 0.0 1.2e-49 168.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 Pex14_N PF04695.8 CAM71830.1 - 0.024 14.7 0.3 0.064 13.2 0.2 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region UNC45-central PF11701.3 CAM71830.1 - 0.024 14.2 0.6 0.045 13.3 0.4 1.4 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central DUF445 PF04286.7 CAM71830.1 - 0.034 13.6 2.5 0.048 13.2 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) FANCI_S1-cap PF14674.1 CAM71830.1 - 0.069 13.2 0.5 1.2 9.2 0.1 2.4 2 0 0 2 2 2 0 FANCI solenoid 1 cap CRISPR_Cse2 PF09485.5 CAM71830.1 - 4.8 7.2 7.3 1.3e+02 2.5 5.0 2.3 1 1 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Prenyltrans PF00432.16 CAM71831.1 - 6.7e-71 233.4 17.7 1.2e-14 53.5 0.3 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CAM71831.1 - 5.3e-43 146.0 0.1 1.7e-18 67.0 0.0 3.3 1 1 2 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 CAM71831.1 - 5e-15 55.4 0.1 4.5e-06 26.6 0.0 4.0 1 1 3 4 4 4 4 Prenyltransferase-like A2M_comp PF07678.9 CAM71831.1 - 0.042 13.0 0.0 5.4 6.1 0.0 3.7 2 1 3 5 5 5 0 A-macroglobulin complement component GAF_2 PF13185.1 CAM71833.1 - 0.024 15.1 0.1 0.089 13.2 0.1 2.1 1 0 0 1 1 1 0 GAF domain UCH PF00443.24 CAM71834.1 - 2.5e-36 125.2 0.1 3.6e-36 124.6 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CAM71834.1 - 2.6e-17 63.1 0.0 4.4e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Herpes_HEPA PF03324.9 CAM71835.1 - 0.018 15.0 0.0 0.094 12.7 0.0 2.2 2 0 0 2 2 2 0 Herpesvirus DNA helicase/primase complex associated protein DUF342 PF03961.8 CAM71835.1 - 0.12 10.7 3.8 9.4 4.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF342) DnaJ PF00226.26 CAM71836.1 - 3.8e-08 32.9 0.1 2.1e-07 30.5 0.1 2.0 2 0 0 2 2 2 1 DnaJ domain GRIP PF01465.15 CAM71837.1 - 2.4e-12 46.1 0.1 5.4e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 GRIP domain DUF4618 PF15397.1 CAM71837.1 - 0.0018 17.6 26.4 0.0035 16.7 0.0 3.9 3 1 0 3 3 2 2 Domain of unknown function (DUF4618) Filament PF00038.16 CAM71837.1 - 0.034 13.6 33.2 0.083 12.3 8.3 4.6 4 1 1 5 5 5 0 Intermediate filament protein TPR_MLP1_2 PF07926.7 CAM71837.1 - 1.1 9.0 36.3 1.1 9.0 8.2 3.8 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein CorA PF01544.13 CAM71837.1 - 1.4 7.8 11.1 0.41 9.6 4.9 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Bacillus_HBL PF05791.6 CAM71837.1 - 2 7.7 10.9 4.3 6.6 2.8 2.9 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) GAGA_bind PF06217.7 CAM71837.1 - 3.7 7.4 15.4 2.4 8.0 8.9 1.8 1 1 1 2 2 2 0 GAGA binding protein-like family AAA_13 PF13166.1 CAM71837.1 - 5.1 5.4 14.2 2.1 6.6 6.6 2.0 2 0 0 2 2 2 0 AAA domain IKKbetaNEMObind PF12179.3 CAM71837.1 - 5.7 6.8 8.2 25 4.7 0.2 3.8 2 1 1 3 3 3 0 I-kappa-kinase-beta NEMO binding domain Exonuc_VII_L PF02601.10 CAM71837.1 - 6.5 5.8 26.8 0.098 11.8 10.7 2.7 2 1 1 3 3 3 0 Exonuclease VII, large subunit LURAP PF14854.1 CAM71837.1 - 7.5 6.2 8.9 0.27 10.9 0.3 3.0 3 1 1 4 4 4 0 Leucine rich adaptor protein Reo_sigmaC PF04582.7 CAM71837.1 - 9.9 5.2 9.9 0.38 9.8 1.2 2.6 3 0 0 3 3 3 0 Reovirus sigma C capsid protein NAD_binding_3 PF03447.11 CAM71839.1 - 0.0017 18.7 2.1 0.037 14.4 0.3 3.7 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain Abhydrolase_6 PF12697.2 CAM71840.1 - 1.5e-11 44.5 0.3 2.2e-11 44.0 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAM71840.1 - 7.7e-05 22.3 0.0 0.0013 18.3 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CAM71840.1 - 0.00087 19.0 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1620 PF07774.8 CAM71841.2 - 4.3e-51 173.2 0.0 8.7e-51 172.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) GFA PF04828.9 CAM71841.2 - 0.15 12.0 0.2 0.49 10.3 0.0 1.9 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF4488 PF14869.1 CAM71842.1 - 0.031 13.8 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4488) DHC_N2 PF08393.8 CAM71844.2 - 2.1e-119 398.7 0.7 2.1e-119 398.7 0.5 5.1 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 CAM71844.2 - 6.3e-114 381.5 0.0 6.3e-114 381.5 0.0 1.8 2 0 0 2 2 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 CAM71844.2 - 9.9e-84 280.4 0.0 3.3e-82 275.4 0.0 2.8 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 DHC_N1 PF08385.7 CAM71844.2 - 7.7e-35 120.3 7.3 1.1e-34 119.8 0.0 3.8 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 AAA_5 PF07728.9 CAM71844.2 - 3.3e-34 117.5 0.0 3e-21 75.5 0.0 5.7 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_9 PF12781.2 CAM71844.2 - 2.2e-33 115.0 1.0 5.4e-33 113.7 0.0 2.2 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 CAM71844.2 - 8.7e-27 93.7 0.2 4.7e-26 91.3 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 MT PF12777.2 CAM71844.2 - 6.4e-26 90.9 11.8 1.3e-25 89.8 8.2 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 CAM71844.2 - 1.3e-18 67.0 0.1 2.2e-17 63.0 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 CAM71844.2 - 1.4e-12 47.9 0.0 0.00077 19.6 0.0 4.7 3 0 0 3 3 3 3 AAA domain AAA_16 PF13191.1 CAM71844.2 - 2.7e-12 47.0 9.3 0.00011 22.2 0.0 6.5 8 0 0 8 8 5 3 AAA ATPase domain AAA PF00004.24 CAM71844.2 - 9.7e-11 41.9 2.6 0.017 15.2 0.0 4.4 4 0 0 4 4 3 3 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CAM71844.2 - 6.4e-09 36.6 0.3 0.0002 22.1 0.0 5.6 5 0 0 5 5 3 1 AAA domain AAA_28 PF13521.1 CAM71844.2 - 1.8e-07 31.2 0.0 0.026 14.4 0.0 4.3 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.17 CAM71844.2 - 2.9e-07 30.6 0.0 0.11 12.6 0.0 3.7 3 0 0 3 3 3 1 RNA helicase AAA_33 PF13671.1 CAM71844.2 - 3e-07 30.3 0.0 0.0042 16.9 0.0 3.6 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 CAM71844.2 - 8.1e-07 28.3 0.0 0.00061 19.0 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 CAM71844.2 - 3e-06 27.5 6.2 0.002 18.4 0.0 4.5 4 0 0 4 4 2 2 ABC transporter AAA_30 PF13604.1 CAM71844.2 - 3e-06 26.9 0.5 0.013 15.0 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_14 PF13173.1 CAM71844.2 - 4.6e-06 26.5 0.0 0.06 13.2 0.0 4.2 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 CAM71844.2 - 5.8e-06 26.6 0.3 0.0033 17.7 0.0 4.9 4 0 0 4 4 4 1 AAA domain NACHT PF05729.7 CAM71844.2 - 1.3e-05 24.8 0.3 0.16 11.6 0.0 3.3 3 0 0 3 3 2 2 NACHT domain Zeta_toxin PF06414.7 CAM71844.2 - 4.5e-05 22.6 0.1 0.18 10.9 0.0 3.8 3 0 0 3 3 3 1 Zeta toxin AAA_19 PF13245.1 CAM71844.2 - 0.0001 21.9 0.1 0.18 11.5 0.0 4.0 3 0 0 3 3 3 1 Part of AAA domain AAA_29 PF13555.1 CAM71844.2 - 0.00047 19.6 0.0 0.01 15.3 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain Arch_ATPase PF01637.13 CAM71844.2 - 0.00057 19.6 12.0 0.12 12.0 0.0 4.5 5 0 0 5 5 3 2 Archaeal ATPase SRPRB PF09439.5 CAM71844.2 - 0.00069 18.8 1.1 0.036 13.2 0.0 3.2 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit AAA_10 PF12846.2 CAM71844.2 - 0.00079 18.9 5.2 0.031 13.7 0.1 3.8 4 0 0 4 4 3 1 AAA-like domain AAA_24 PF13479.1 CAM71844.2 - 0.00096 18.7 0.5 7.9 5.9 0.0 4.3 4 0 0 4 4 4 0 AAA domain MobB PF03205.9 CAM71844.2 - 0.0014 18.3 0.2 0.048 13.3 0.0 3.3 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B Laminin_II PF06009.7 CAM71844.2 - 0.0014 18.3 3.0 0.0014 18.3 2.1 4.8 5 0 0 5 5 4 1 Laminin Domain II Mg_chelatase PF01078.16 CAM71844.2 - 0.0031 16.7 0.0 4 6.5 0.0 3.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI UPF0079 PF02367.12 CAM71844.2 - 0.0041 16.7 0.1 2 8.0 0.0 3.7 3 0 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 AAA_21 PF13304.1 CAM71844.2 - 0.0058 16.6 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 CAM71844.2 - 0.0065 16.4 0.1 3.5 7.5 0.0 3.5 3 0 0 3 3 3 0 50S ribosome-binding GTPase cobW PF02492.14 CAM71844.2 - 0.014 14.8 2.6 1.6 8.1 0.0 3.3 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 CAM71844.2 - 0.035 13.6 1.4 1.3 8.5 0.0 3.5 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein ArgK PF03308.11 CAM71844.2 - 0.052 12.3 0.0 0.052 12.3 0.0 2.7 3 0 0 3 3 3 0 ArgK protein BHD_2 PF10404.4 CAM71844.2 - 0.095 13.0 1.9 4.9 7.5 0.5 2.9 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 2 Guanylate_kin PF00625.16 CAM71844.2 - 0.1 12.0 0.0 0.1 12.0 0.0 4.1 4 0 0 4 4 3 0 Guanylate kinase SMC_N PF02463.14 CAM71844.2 - 0.36 10.0 0.0 15 4.7 0.0 2.7 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CAM71844.2 - 2.2 8.5 0.0 2.2 8.5 0.0 7.5 9 0 0 9 9 7 0 AAA domain zf-CCHC_3 PF13917.1 CAM71845.1 - 6.4e-13 48.2 0.9 1.2e-12 47.3 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle eIF3g PF12353.3 CAM71845.1 - 0.00041 20.2 1.0 0.00041 20.2 0.7 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G DUF1193 PF06702.7 CAM71846.1 - 3.1e-06 26.7 0.0 6.4e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1193) Metallophos PF00149.23 CAM71847.1 - 1.4e-35 122.4 0.0 1.9e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Complex1_LYR PF05347.10 CAM71850.1 - 0.076 12.8 0.5 0.18 11.6 0.4 1.7 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Robl_LC7 PF03259.12 CAM71851.1 - 0.024 14.2 0.0 0.04 13.4 0.0 1.6 1 1 0 1 1 1 0 Roadblock/LC7 domain BRCT PF00533.21 CAM71852.1 - 4.6e-08 33.1 0.0 3.3e-05 23.9 0.0 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain FHA PF00498.21 CAM71852.1 - 2.6e-07 30.6 0.0 4.8e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 FHA domain PTCB-BRCT PF12738.2 CAM71852.1 - 9.8e-06 25.3 0.0 2.1e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain Glycos_trans_3N PF02885.12 CAM71852.1 - 0.15 11.6 4.8 0.2 11.2 0.0 2.8 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain Kinesin PF00225.18 CAM71854.2 - 2.9e-105 351.7 0.0 2.9e-105 351.7 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain Pex24p PF06398.6 CAM71854.2 - 7.2e-08 31.6 0.5 1.4e-07 30.6 0.3 1.4 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3573 PF12097.3 CAM71854.2 - 0.17 10.4 3.1 0.39 9.2 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Cullin_binding PF03556.10 CAM71855.1 - 1.4e-14 54.2 0.4 2.4e-14 53.4 0.3 1.3 1 0 0 1 1 1 1 Cullin binding cNMP_binding PF00027.24 CAM71857.1 - 1.1e-10 41.2 0.1 3.9e-10 39.3 0.0 2.1 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Gar1 PF04410.9 CAM71858.1 - 5.6e-37 126.5 0.2 5.6e-37 126.5 0.1 2.1 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region zf-DHHC PF01529.15 CAM71859.1 - 9.9e-16 57.6 3.2 1.7e-15 56.8 2.0 1.5 1 1 1 2 2 2 1 DHHC palmitoyltransferase MatC_N PF07158.6 CAM71859.1 - 0.019 14.7 1.6 0.02 14.7 0.1 1.7 2 0 0 2 2 2 0 Dicarboxylate carrier protein MatC N-terminus Cys_knot PF00007.17 CAM71859.1 - 0.026 14.5 0.9 0.045 13.8 0.6 1.4 1 0 0 1 1 1 0 Cystine-knot domain zinc_ribbon_2 PF13240.1 CAM71859.1 - 0.1 12.1 2.0 0.33 10.5 1.4 1.9 1 1 0 1 1 1 0 zinc-ribbon domain Coatomer_WDAD PF04053.9 CAM71860.1 - 2.1e-97 326.7 0.2 3.1e-97 326.1 0.1 1.2 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 CAM71860.1 - 2.1e-87 293.4 0.0 3.1e-87 292.8 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 CAM71860.1 - 1.8e-48 160.7 19.0 1e-10 41.0 0.1 6.9 6 0 0 6 6 6 6 WD domain, G-beta repeat HSDR_N PF04313.9 CAM71860.1 - 0.021 14.5 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) ComFB PF10719.4 CAM71860.1 - 0.065 12.9 0.4 0.21 11.3 0.3 1.8 1 0 0 1 1 1 0 Late competence development protein ComFB TPR_16 PF13432.1 CAM71860.1 - 1.9 9.2 9.7 5.2 7.8 0.4 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat ESSS PF10183.4 CAM71861.1 - 1.2e-13 51.3 5.6 1.4e-13 51.1 3.9 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) PI3_PI4_kinase PF00454.22 CAM71863.1 - 6.3e-52 176.3 0.2 1.4e-51 175.2 0.2 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 CAM71863.1 - 6.2e-41 140.5 3.7 9.7e-41 139.9 1.2 2.3 2 1 0 2 2 2 1 FAT domain Rapamycin_bind PF08771.6 CAM71863.1 - 1.3e-31 108.5 0.9 6.5e-31 106.3 0.2 2.6 2 0 0 2 2 2 1 Rapamycin binding domain DUF3385 PF11865.3 CAM71863.1 - 6e-25 88.0 0.0 2.9e-24 85.7 0.0 2.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3385) FATC PF02260.15 CAM71863.1 - 6.9e-12 44.5 0.3 2.7e-11 42.7 0.2 2.2 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 CAM71863.1 - 5.7e-05 22.8 4.6 1.1 9.4 0.0 6.4 6 0 0 6 6 6 1 HEAT repeat ADIP PF11559.3 CAM71864.1 - 0.00035 20.5 4.8 0.0004 20.3 3.3 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Rho_Binding PF08912.6 CAM71864.1 - 0.0018 18.5 4.7 0.0035 17.6 1.4 2.4 1 1 1 2 2 2 1 Rho Binding YkyA PF10368.4 CAM71864.1 - 0.0027 17.0 5.8 0.003 16.9 4.0 1.0 1 0 0 1 1 1 1 Putative cell-wall binding lipoprotein Pox_F11 PF04943.7 CAM71864.1 - 0.0053 15.6 2.0 0.0063 15.4 1.4 1.0 1 0 0 1 1 1 1 Poxvirus F11 protein Occludin_ELL PF07303.8 CAM71864.1 - 0.0079 16.9 1.5 0.0095 16.6 1.0 1.1 1 0 0 1 1 1 1 Occludin homology domain EIF_2_alpha PF07541.7 CAM71864.1 - 0.008 15.8 2.0 0.42 10.3 0.1 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit GAS PF13851.1 CAM71864.1 - 0.019 14.1 7.3 0.022 13.9 5.1 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CorA PF01544.13 CAM71864.1 - 0.028 13.4 2.0 0.03 13.3 1.4 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein IFT57 PF10498.4 CAM71864.1 - 0.029 13.1 3.5 0.03 13.0 2.5 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Apt1 PF10351.4 CAM71864.1 - 0.046 12.5 3.5 0.051 12.4 2.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Lebercilin PF15619.1 CAM71864.1 - 0.095 12.1 7.3 0.25 10.7 5.1 1.6 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease M_domain PF12938.2 CAM71864.1 - 0.1 12.4 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 M domain of GW182 CCDC144C PF14915.1 CAM71864.1 - 0.12 11.2 7.4 0.14 11.0 5.2 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region DUF4061 PF13270.1 CAM71864.1 - 0.13 12.3 1.0 0.2 11.7 0.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4061) PilJ PF13675.1 CAM71864.1 - 0.15 12.4 1.6 0.32 11.3 1.1 1.7 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Sec20 PF03908.8 CAM71864.1 - 0.15 11.7 2.4 0.36 10.5 0.3 2.1 1 1 1 2 2 2 0 Sec20 V_ATPase_I PF01496.14 CAM71864.1 - 0.17 9.7 2.7 0.19 9.5 1.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIVA PF05103.8 CAM71864.1 - 0.23 11.5 5.9 0.11 12.5 1.1 2.2 1 1 0 1 1 1 0 DivIVA protein DUF2422 PF10337.4 CAM71864.1 - 0.24 10.1 2.4 0.26 10.0 1.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) PspB PF06667.7 CAM71864.1 - 0.25 11.2 3.7 2.6 8.0 0.2 2.5 1 1 2 3 3 3 0 Phage shock protein B DUF1366 PF07104.6 CAM71864.1 - 0.3 10.7 3.8 1.4 8.5 0.4 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1366) Atg14 PF10186.4 CAM71864.1 - 0.4 9.5 4.4 0.43 9.4 3.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 CAM71864.1 - 0.41 10.2 8.8 0.59 9.7 6.1 1.3 1 1 0 1 1 1 0 IncA protein DUF1151 PF06625.6 CAM71864.1 - 0.46 10.2 4.4 0.62 9.8 2.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1151) DUF4164 PF13747.1 CAM71864.1 - 0.47 10.6 6.8 2.4 8.3 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Cluap1 PF10234.4 CAM71864.1 - 0.79 8.8 7.8 1.7 7.8 5.4 1.6 1 1 0 1 1 1 0 Clusterin-associated protein-1 CENP-Q PF13094.1 CAM71864.1 - 0.8 9.7 9.5 1.7 8.6 6.6 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Prefoldin_2 PF01920.15 CAM71864.1 - 0.82 9.4 8.7 0.37 10.5 2.9 2.2 1 1 1 2 2 2 0 Prefoldin subunit TPR_MLP1_2 PF07926.7 CAM71864.1 - 0.85 9.3 9.7 3.4 7.4 1.9 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DivIC PF04977.10 CAM71864.1 - 1.3 8.5 9.7 0.72 9.3 0.3 2.7 1 1 2 3 3 3 0 Septum formation initiator CENP-F_leu_zip PF10473.4 CAM71864.1 - 1.5 8.7 10.8 2.5 7.9 7.5 1.4 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FliD_N PF02465.13 CAM71864.1 - 1.5 9.2 6.2 7 7.0 4.3 1.9 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus APG6 PF04111.7 CAM71864.1 - 1.9 7.4 6.7 2.1 7.3 4.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Seryl_tRNA_N PF02403.17 CAM71864.1 - 2.5 8.1 7.9 0.61 10.1 2.9 1.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF724 PF05266.9 CAM71864.1 - 3.4 7.2 7.5 13 5.3 5.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Rcd1 PF04078.8 CAM71865.1 - 5.1e-108 359.8 0.9 6e-108 359.6 0.6 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like RRM_1 PF00076.17 CAM71866.1 - 2.8e-29 100.5 0.0 1.9e-14 53.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM71866.1 - 2.1e-25 88.4 0.0 1e-13 51.0 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM71866.1 - 2.5e-09 36.8 0.1 0.0038 17.0 0.0 4.0 3 2 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 CAM71866.1 - 0.006 16.5 0.1 0.57 10.2 0.0 2.6 2 1 0 2 2 2 1 RNA binding domain RRM_3 PF08777.6 CAM71866.1 - 0.0068 16.2 0.0 10 6.0 0.0 3.4 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 CAM71866.1 - 0.0078 15.9 0.0 0.33 10.7 0.0 2.7 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif FAM176 PF14851.1 CAM71867.1 - 0.018 14.7 1.2 0.029 14.0 0.8 1.3 1 0 0 1 1 1 0 FAM176 family Tmemb_170 PF10190.4 CAM71867.1 - 0.16 12.0 4.0 0.21 11.6 2.8 1.1 1 0 0 1 1 1 0 Putative transmembrane protein 170 WD40 PF00400.27 CAM71868.1 - 1.2e-09 37.7 9.2 0.00065 19.4 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat gag_pre-integrs PF13976.1 CAM71869.1 - 0.021 14.4 0.7 1.4 8.5 0.0 2.6 2 0 0 2 2 2 0 GAG-pre-integrase domain Myb_DNA-bind_6 PF13921.1 CAM71869.1 - 0.052 13.6 0.3 1.1 9.3 0.1 2.6 1 1 1 2 2 2 0 Myb-like DNA-binding domain Glyco_trans_2_3 PF13632.1 CAM71869.1 - 0.091 12.4 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family group 2 ARD PF03079.9 CAM71870.1 - 1.5e-25 89.9 0.0 1.5e-25 89.9 0.0 2.1 2 0 0 2 2 2 1 ARD/ARD' family Cupin_2 PF07883.6 CAM71870.1 - 1.2e-06 27.8 0.0 3.1e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 CAM71870.1 - 0.00061 19.1 0.0 0.0015 17.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF861) AraC_binding PF02311.14 CAM71870.1 - 0.001 18.7 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_6 PF12852.2 CAM71870.1 - 0.0012 18.5 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_8 PF13621.1 CAM71870.1 - 0.0047 16.4 1.7 0.014 14.9 0.0 2.1 2 0 0 2 2 2 1 Cupin-like domain Cupin_1 PF00190.17 CAM71870.1 - 0.023 14.1 0.0 0.042 13.2 0.0 1.5 1 0 0 1 1 1 0 Cupin Ehbp PF10622.4 CAM71870.1 - 0.069 13.0 0.2 0.94 9.4 0.0 2.5 2 1 1 3 3 3 0 Energy-converting hydrogenase B subunit P (EhbP) SAPS PF04499.10 CAM71870.1 - 0.11 11.1 1.6 0.11 11.0 1.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ycf1 PF05758.7 CAM71870.1 - 0.13 9.9 5.2 0.16 9.6 3.6 1.2 1 0 0 1 1 1 0 Ycf1 YqfQ PF14181.1 CAM71870.1 - 6.5 6.7 7.7 11 6.0 5.3 1.4 1 0 0 1 1 1 0 YqfQ-like protein ESSS PF10183.4 CAM71872.1 - 1.2e-13 51.3 5.6 1.4e-13 51.1 3.9 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) adh_short PF00106.20 CAM71873.1 - 4.9e-09 36.3 7.5 1.5e-08 34.7 5.2 1.7 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 CAM71873.1 - 0.0027 17.1 0.1 0.0054 16.1 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CAM71873.1 - 0.025 13.5 0.3 0.075 11.9 0.1 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain Proteasome PF00227.21 CAM71874.1 - 1.9e-25 89.2 0.0 2.3e-25 88.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Amastin PF07344.6 CAM71875.1 - 1e-53 181.0 15.4 1.2e-53 180.8 10.7 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CAM71875.1 - 0.00047 19.9 11.6 0.00047 19.9 8.0 1.9 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF1700 PF08006.6 CAM71875.1 - 5.5 6.2 10.2 1.8 7.8 3.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) Tetraspannin PF00335.15 CAM71875.1 - 6.5 5.9 16.2 1.3 8.2 8.7 1.7 1 1 0 1 1 1 0 Tetraspanin family TrbC PF04956.8 CAM71875.1 - 7.2 6.6 10.5 1.7 8.7 0.8 2.9 3 0 0 3 3 3 0 TrbC/VIRB2 family EF1_GNE PF00736.14 CAM71876.1 - 1.5e-29 101.5 1.8 2.5e-29 100.8 1.2 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain GST_C_3 PF14497.1 CAM71876.1 - 0.017 15.5 0.5 0.048 14.1 0.0 2.0 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain HTH_1 PF00126.22 CAM71876.1 - 0.11 12.2 0.1 7.3 6.4 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family DUF3275 PF11679.3 CAM71876.1 - 0.18 11.4 2.4 0.27 10.8 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Stm1_N PF09598.5 CAM71876.1 - 6.3 7.5 10.2 8.1 7.2 1.2 2.5 2 0 0 2 2 2 0 Stm1 Pcc1 PF09341.5 CAM71877.1 - 1.8e-16 59.9 0.2 2.2e-16 59.6 0.1 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 Amastin PF07344.6 CAM71879.1 - 4.8e-52 175.6 10.3 5.6e-52 175.4 7.1 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein DuoxA PF10204.4 CAM71879.1 - 0.02 13.9 5.7 0.03 13.3 3.9 1.3 1 0 0 1 1 1 0 Dual oxidase maturation factor Claudin_2 PF13903.1 CAM71879.1 - 0.28 10.8 18.6 0.045 13.4 9.2 2.1 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.6 CAM71879.1 - 8.3 6.1 11.5 1.9 8.1 0.2 3.2 1 1 2 3 3 3 0 Tight junction protein, Claudin-like Amastin PF07344.6 CAM71880.1 - 5.7e-54 181.9 5.8 6.7e-54 181.7 4.0 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CAM71880.1 - 0.0041 16.8 7.6 0.0041 16.8 5.3 2.1 2 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 CAM71880.1 - 0.035 13.7 7.1 0.019 14.5 1.6 2.4 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family 2-Hacid_dh_C PF02826.14 CAM71881.1 - 2.1e-43 147.5 0.0 2.9e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 CAM71881.1 - 9.9e-06 25.4 0.2 2.1e-05 24.3 0.1 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.1 CAM71881.1 - 1.7e-05 24.8 0.0 3.2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding IlvN PF07991.7 CAM71881.1 - 6.4e-05 22.3 0.1 0.00013 21.3 0.0 1.6 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 CAM71881.1 - 0.00063 20.1 0.1 0.0026 18.1 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.16 CAM71881.1 - 0.0015 18.3 0.3 0.0069 16.2 0.2 2.1 2 1 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh PF00389.25 CAM71881.1 - 0.0045 16.4 0.0 0.075 12.4 0.0 2.2 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.16 CAM71881.1 - 0.11 12.0 0.2 0.6 9.6 0.2 2.1 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF1614 PF07758.6 CAM71882.1 - 0.028 14.1 0.4 0.037 13.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1614) Tim17 PF02466.14 CAM71882.1 - 0.065 13.2 4.2 0.13 12.2 2.9 1.4 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family ubiquitin PF00240.18 CAM71883.1 - 1.3e-16 59.7 0.0 1.5e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CAM71883.1 - 1.2e-07 31.2 0.0 1.3e-07 31.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 CAM71883.1 - 0.001 18.9 0.1 0.002 17.9 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CAM71883.1 - 0.026 14.7 0.0 0.06 13.6 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-like domain DoxX PF07681.7 CAM71884.1 - 0.0015 18.8 7.0 0.0015 18.8 4.9 1.6 2 0 0 2 2 2 1 DoxX DUF4239 PF14023.1 CAM71884.1 - 0.01 15.2 0.4 0.017 14.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) PRA1 PF03208.14 CAM71884.1 - 0.066 12.5 2.6 0.11 11.8 1.8 1.4 1 0 0 1 1 1 0 PRA1 family protein SIR2 PF02146.12 CAM71885.1 - 5e-45 153.3 0.0 6.2e-45 153.1 0.0 1.1 1 0 0 1 1 1 1 Sir2 family PLDc_2 PF13091.1 CAM71886.1 - 4.1e-25 87.9 0.0 2.8e-18 65.8 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 CAM71886.1 - 4.4e-08 32.6 2.0 0.0069 16.1 0.6 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif GCV_H PF01597.14 CAM71887.1 - 0.00082 19.0 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Glycine cleavage H-protein Epimerase PF01370.16 CAM71889.1 - 8.6e-16 58.0 0.0 1.3e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CAM71889.1 - 1.2e-11 45.0 0.0 2.6e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CAM71889.1 - 3e-07 29.9 0.0 1.9e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.14 CAM71889.1 - 1.1e-06 27.6 0.1 2.7e-06 26.2 0.1 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CAM71889.1 - 0.025 13.4 0.0 0.051 12.5 0.0 1.5 1 1 0 1 1 1 0 Male sterility protein CesT PF05932.8 CAM71891.1 - 1.7e-11 44.0 0.2 4.1e-11 42.7 0.2 1.8 1 0 0 1 1 1 1 Tir chaperone protein (CesT) family ubiquitin PF00240.18 CAM71891.1 - 0.0027 17.0 0.0 0.015 14.6 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 CAM71891.1 - 0.014 15.0 0.0 0.031 13.9 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like LRS4 PF10422.4 CAM71891.1 - 0.028 13.8 1.3 0.042 13.2 0.9 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 bZIP_1 PF00170.16 CAM71891.1 - 0.21 11.5 0.1 0.21 11.5 0.1 3.5 3 1 1 4 4 4 0 bZIP transcription factor DUF1640 PF07798.6 CAM71891.1 - 1.9 8.5 5.7 0.75 9.8 1.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Complex1_LYR PF05347.10 CAM71892.1 - 0.032 14.0 0.0 0.11 12.3 0.0 1.9 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Prefoldin PF02996.12 CAM71892.1 - 0.037 13.6 0.0 0.14 11.7 0.0 2.0 2 0 0 2 2 2 0 Prefoldin subunit Gemini_mov PF01708.11 CAM71893.1 - 1.8 8.1 3.9 3.7 7.1 2.7 1.5 1 0 0 1 1 1 0 Geminivirus putative movement protein Elf1 PF05129.8 CAM71894.1 - 0.0033 17.0 0.5 0.0033 17.0 0.3 3.0 3 1 0 3 3 3 1 Transcription elongation factor Elf1 like zf-CCHC PF00098.18 CAM71894.1 - 0.0045 16.8 3.1 0.0045 16.8 2.1 3.4 3 0 0 3 3 3 1 Zinc knuckle L1R_F9L PF02442.12 CAM71894.1 - 0.54 9.7 2.7 1 8.8 1.8 1.3 1 0 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses eIF3g PF12353.3 CAM71894.1 - 0.68 9.8 19.9 1 9.2 3.8 3.6 1 1 2 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G WW PF00397.21 CAM71894.1 - 1.1 9.1 6.4 0.53 10.2 2.4 2.1 2 0 0 2 2 2 0 WW domain Cryptochrome_C PF12546.3 CAM71895.1 - 0.067 13.8 0.5 0.16 12.6 0.1 1.8 2 0 0 2 2 2 0 Blue/Ultraviolet sensing protein C terminal ERM PF00769.14 CAM71896.2 - 2.9e-18 66.3 265.3 0.00032 20.3 21.5 10.8 3 2 9 12 12 12 9 Ezrin/radixin/moesin family Cast PF10174.4 CAM71896.2 - 3.1e-15 55.3 232.2 3.9e-05 21.9 23.5 7.6 4 2 4 8 8 8 5 RIM-binding protein of the cytomatrix active zone CENP-F_leu_zip PF10473.4 CAM71896.2 - 2.6e-12 46.8 229.7 9.5e-06 25.5 5.6 12.4 4 2 9 13 13 13 9 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phage_lysis PF03245.8 CAM71896.2 - 8e-07 29.0 239.0 0.18 11.7 7.2 15.4 3 2 12 15 15 15 13 Bacteriophage Rz lysis protein ADIP PF11559.3 CAM71896.2 - 0.00013 21.9 226.9 0.23 11.3 5.4 13.6 5 1 10 15 15 15 11 Afadin- and alpha -actinin-Binding DivIVA PF05103.8 CAM71896.2 - 0.0023 18.0 197.8 0.52 10.3 4.2 16.4 3 2 13 16 16 16 12 DivIVA protein APG6 PF04111.7 CAM71896.2 - 0.0042 16.1 10.9 0.0042 16.1 7.5 11.1 3 2 12 15 15 15 12 Autophagy protein Apg6 bZIP_1 PF00170.16 CAM71896.2 - 0.0091 15.9 1.6 0.0091 15.9 1.1 18.4 8 4 19 27 27 27 1 bZIP transcription factor GAS PF13851.1 CAM71896.2 - 0.024 13.8 202.7 0.17 11.0 11.7 13.0 4 2 9 13 13 13 0 Growth-arrest specific micro-tubule binding Shugoshin_N PF07558.6 CAM71896.2 - 5.6 6.7 50.9 35 4.2 0.2 11.5 11 0 0 11 11 11 0 Shugoshin N-terminal coiled-coil region DUF2039 PF10217.4 CAM71897.1 - 3.6e-26 91.0 21.6 5.9e-26 90.3 15.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) Cript PF10235.4 CAM71897.1 - 6 7.2 15.7 0.28 11.5 6.6 1.8 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT Transmemb_17 PF09799.4 CAM71898.1 - 2.1e-29 102.0 11.0 2.8e-29 101.6 7.7 1.2 1 0 0 1 1 1 1 Predicted membrane protein FTR1 PF03239.9 CAM71898.1 - 0.019 13.9 7.2 0.015 14.2 4.3 1.3 1 1 0 1 1 1 0 Iron permease FTR1 family NVEALA PF14055.1 CAM71898.1 - 1.8 8.3 6.2 0.19 11.4 1.0 1.8 2 0 0 2 2 2 0 NVEALA protein Tcp10_C PF07202.8 CAM71900.1 - 0.0012 18.3 0.4 0.002 17.6 0.3 1.2 1 0 0 1 1 1 1 T-complex protein 10 C-terminus Sod_Fe_C PF02777.13 CAM71900.1 - 0.0048 16.7 0.0 0.019 14.7 0.0 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Med3 PF11593.3 CAM71900.1 - 3.4 6.7 13.5 6.3 5.9 9.4 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PK PF00224.16 CAM71908.1 - 4.9e-51 173.3 0.1 5.6e-51 173.2 0.0 1.0 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK PF00224.16 CAM71909.1 - 6.4e-163 541.3 2.3 8.3e-163 540.9 1.6 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 CAM71909.1 - 8.6e-25 86.5 0.2 8.6e-25 86.5 0.1 2.3 3 0 0 3 3 3 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 CAM71909.1 - 8.6e-05 21.5 1.0 0.00037 19.4 0.4 1.9 1 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Galactosyl_T PF01762.16 CAM71910.2 - 8.1e-06 25.5 0.0 4.6e-05 23.1 0.0 2.2 3 0 0 3 3 3 1 Galactosyltransferase Histone PF00125.19 CAM71911.1 - 3.7e-14 52.5 0.8 4.5e-14 52.3 0.6 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CAM71911.1 - 2.6e-05 24.1 0.1 4.3e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 CAM71911.1 - 7.4e-05 22.6 0.1 0.00011 22.0 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.8 CAM71911.1 - 0.00064 19.4 0.0 0.00081 19.0 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 CAM71911.1 - 0.0013 18.5 0.0 0.0014 18.4 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit PCP_red PF08369.5 CAM71911.1 - 0.033 14.0 1.0 0.064 13.1 0.3 1.9 2 1 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit FbpA PF05833.6 CAM71911.1 - 0.049 12.1 0.0 0.057 11.9 0.0 1.0 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF4400 PF14348.1 CAM71911.1 - 0.092 12.1 0.3 0.13 11.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) PK PF00224.16 CAM71912.1 - 8.5e-150 498.1 2.1 1.1e-149 497.8 1.4 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 CAM71912.1 - 1.5e-19 69.6 2.5 1.9e-19 69.3 0.1 2.3 3 0 0 3 3 3 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 CAM71912.1 - 7.2e-05 21.7 1.0 0.00036 19.4 0.7 1.9 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family PI-PLC-X PF00388.14 CAM71913.1 - 6e-57 191.1 0.0 1.1e-56 190.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 CAM71913.1 - 8.2e-34 116.1 0.0 2.4e-33 114.6 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 CAM71913.1 - 3.7e-06 26.8 0.4 0.00047 20.1 0.0 2.7 2 1 1 3 3 3 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_1 PF00036.27 CAM71913.1 - 0.0069 15.6 0.3 0.023 13.9 0.2 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 CAM71913.1 - 0.0082 16.2 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair C2 PF00168.25 CAM71913.1 - 0.14 12.0 0.0 0.36 10.7 0.0 1.7 1 0 0 1 1 1 0 C2 domain Transket_pyr PF02779.19 CAM71914.1 - 1.4e-40 138.6 0.0 2.4e-40 137.9 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CAM71914.1 - 7.8e-35 119.5 0.0 1.8e-34 118.3 0.0 1.6 2 0 0 2 2 2 1 Transketolase, C-terminal domain Shal-type PF11601.3 CAM71914.1 - 0.082 12.4 0.7 0.17 11.4 0.5 1.5 1 0 0 1 1 1 0 Shal-type voltage-gated potassium channels GHL1-3 PF11308.3 CAM71915.1 - 0.057 12.7 4.0 0.28 10.4 0.0 3.0 2 1 0 2 2 2 0 Glycosyl hydrolases related to GH101 family, GHL1-GHL3 Band_7 PF01145.20 CAM71916.1 - 5.9e-27 94.7 1.5 9.4e-27 94.0 1.0 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family TrkH PF02386.11 CAM71917.1 - 9.2e-16 57.3 23.1 9.5e-12 44.1 3.8 4.0 2 2 0 2 2 2 2 Cation transport protein UCR_14kD PF02271.11 CAM71919.1 - 4.3e-09 36.0 0.0 1e-08 34.8 0.0 1.5 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Clat_adaptor_s PF01217.15 CAM71920.1 - 4.7e-10 39.3 0.0 6.5e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain LMBR1 PF04791.11 CAM71921.1 - 1.3e-16 60.3 26.0 2.8e-12 45.9 18.0 2.4 1 1 0 1 1 1 1 LMBR1-like membrane protein CTV_P33 PF07184.6 CAM71921.1 - 0.018 13.8 0.0 0.58 8.9 0.0 2.2 2 0 0 2 2 2 0 Citrus tristeza virus P33 protein Arf PF00025.16 CAM71922.1 - 4.8e-65 218.0 0.1 5.4e-65 217.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 CAM71922.1 - 1.1e-12 47.3 1.8 9.2e-08 31.1 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CAM71922.1 - 2.8e-10 39.7 0.0 3.4e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CAM71922.1 - 1.1e-08 34.4 0.0 1.5e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CAM71922.1 - 1.6e-07 30.8 0.0 1.9e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.22 CAM71922.1 - 3.3e-07 29.9 0.0 1.3e-05 24.6 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CAM71922.1 - 1.2e-06 28.5 0.0 1.8e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CAM71922.1 - 2.9e-06 27.7 0.0 3.8e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 CAM71922.1 - 0.0017 17.6 0.1 0.0063 15.7 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B cobW PF02492.14 CAM71922.1 - 0.016 14.6 0.1 0.19 11.1 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Mito_carr PF00153.22 CAM71924.1 - 2.5e-07 30.2 3.1 0.0048 16.5 0.5 3.0 2 1 1 3 3 3 2 Mitochondrial carrier protein Reo_sigmaC PF04582.7 CAM71927.1 - 0.00019 20.6 55.5 0.02 14.0 3.9 6.6 2 2 3 6 6 6 4 Reovirus sigma C capsid protein APG6 PF04111.7 CAM71927.1 - 0.00073 18.6 12.0 0.00073 18.6 8.3 8.0 2 2 5 8 8 8 3 Autophagy protein Apg6 GAS PF13851.1 CAM71927.1 - 0.0038 16.4 5.1 0.0038 16.4 3.5 7.7 3 2 3 7 7 7 3 Growth-arrest specific micro-tubule binding DUF904 PF06005.7 CAM71927.1 - 0.013 15.7 7.1 0.013 15.7 4.9 11.4 5 4 4 9 9 9 0 Protein of unknown function (DUF904) WD40_alt PF14077.1 CAM71927.1 - 2.8 7.6 12.2 11 5.7 1.2 5.3 5 0 0 5 5 5 0 Alternative WD40 repeat motif CENP-F_leu_zip PF10473.4 CAM71927.1 - 5.1 6.9 129.3 0.29 11.0 10.3 8.9 2 2 6 8 8 8 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NIF PF03031.13 CAM71928.1 - 9.4e-33 113.1 0.0 1.3e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase PF00702.21 CAM71928.1 - 0.0063 16.9 0.0 0.0082 16.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CAM71928.1 - 0.013 15.6 0.0 0.033 14.4 0.0 1.5 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase HAD PF12710.2 CAM71928.1 - 0.015 15.4 0.0 0.029 14.5 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF705 PF05152.7 CAM71928.1 - 0.068 12.1 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) SapA PF02199.10 CAM71928.1 - 0.12 12.1 0.3 0.28 10.9 0.2 1.6 1 0 0 1 1 1 0 Saposin A-type domain DUF1242 PF06842.7 CAM71930.1 - 3.6e-13 48.7 1.6 5.2e-13 48.2 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) DnaJ PF00226.26 CAM71932.1 - 3.3e-05 23.5 0.1 0.00018 21.1 0.0 2.1 1 1 0 1 1 1 1 DnaJ domain zf-CCCH PF00642.19 CAM71932.1 - 0.0037 16.8 4.5 0.0087 15.7 3.1 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ribosomal_L7Ae PF01248.21 CAM71933.1 - 8.6e-25 86.0 0.0 9.7e-25 85.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ArfGap PF01412.13 CAM71935.2 - 1.4e-28 99.0 0.0 3e-28 97.9 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-dskA_traR PF01258.12 CAM71935.2 - 0.54 10.0 3.0 0.92 9.3 0.1 2.7 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger 3HCDH PF00725.17 CAM71938.1 - 2.2e-09 37.5 0.2 0.00067 20.0 0.1 2.6 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Rrf2 PF02082.15 CAM71938.1 - 0.013 15.6 0.1 0.029 14.5 0.1 1.5 1 0 0 1 1 1 0 Transcriptional regulator Ank_2 PF12796.2 CAM71940.1 - 1.7e-13 50.7 0.0 1.9e-11 44.1 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CAM71940.1 - 2e-12 46.2 0.1 0.0018 17.9 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 CAM71940.1 - 2.3e-07 30.3 0.1 0.58 10.5 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 CAM71940.1 - 2.4e-06 27.5 0.1 0.0031 17.7 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 CAM71940.1 - 6.5e-06 26.5 0.0 0.028 14.9 0.0 2.9 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Aminotran_1_2 PF00155.16 CAM71941.1 - 4.9e-49 167.2 0.0 5.8e-49 166.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CAM71941.1 - 0.055 12.6 0.0 0.089 11.9 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 CAM71941.1 - 0.11 11.4 0.0 4 6.3 0.0 2.0 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family adh_short PF00106.20 CAM71942.1 - 2.3e-29 102.4 2.0 4.1e-29 101.6 1.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CAM71942.1 - 3.8e-16 59.2 1.6 3.8e-16 59.2 1.1 1.9 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 CAM71942.1 - 1.1e-12 48.2 0.1 1.5e-12 47.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 CAM71942.1 - 0.0032 16.4 0.0 0.0037 16.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 CAM71942.1 - 0.016 14.9 0.0 0.051 13.3 0.0 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 CAM71942.1 - 0.036 14.0 1.7 0.86 9.5 1.2 2.5 1 1 0 1 1 1 0 NADH(P)-binding Glyco_tranf_2_3 PF13641.1 CAM71942.1 - 0.054 13.2 0.3 0.11 12.3 0.2 1.5 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Epimerase PF01370.16 CAM71942.1 - 0.061 12.7 0.1 0.09 12.1 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 7kD_coat PF02495.12 CAM71942.1 - 0.16 11.4 0.5 0.33 10.4 0.4 1.5 1 0 0 1 1 1 0 7kD viral coat protein Methyltransf_26 PF13659.1 CAM71943.1 - 0.1 12.6 3.0 0.11 12.5 0.6 2.1 2 1 0 2 2 2 0 Methyltransferase domain DEAD PF00270.24 CAM71946.1 - 2e-43 147.8 0.5 2.9e-43 147.3 0.4 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM71946.1 - 4e-25 87.4 0.3 8.9e-25 86.3 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CAM71946.1 - 0.011 15.8 0.4 0.037 14.1 0.3 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 CAM71946.1 - 0.12 12.5 1.0 1.9 8.6 0.7 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Thioredoxin PF00085.15 CAM71947.1 - 2e-06 27.4 0.0 4.5e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CAM71947.1 - 9.6e-05 22.4 0.1 0.014 15.4 0.0 2.5 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.1 CAM71947.1 - 0.0017 18.3 0.1 0.0046 16.9 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CAM71947.1 - 0.025 14.7 0.0 0.36 11.0 0.0 2.7 2 1 0 2 2 2 0 Thioredoxin-like domain Thioredoxin_9 PF14595.1 CAM71947.1 - 0.042 13.4 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Ribosomal_S3Ae PF01015.13 CAM71949.1 - 1.1e-61 207.5 4.9 1.3e-61 207.2 3.4 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family TMEM156 PF15106.1 CAM71949.1 - 0.033 13.4 0.0 0.049 12.8 0.0 1.2 1 0 0 1 1 1 0 TMEM156 protein family DUF2828 PF11443.3 CAM71949.1 - 0.04 12.1 1.2 0.046 11.9 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DNA_pol3_delt_C PF14840.1 CAM71949.1 - 0.13 12.4 2.6 0.19 11.8 1.4 1.5 1 1 0 1 1 1 0 Processivity clamp loader gamma complex DNA pol III C-term Ribosomal_S3Ae PF01015.13 CAM71950.1 - 6.1e-62 208.4 4.3 7.2e-62 208.1 3.0 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family TMEM156 PF15106.1 CAM71950.1 - 0.034 13.4 0.0 0.049 12.8 0.0 1.2 1 0 0 1 1 1 0 TMEM156 protein family DNA_pol3_delt_C PF14840.1 CAM71950.1 - 0.13 12.4 2.6 0.19 11.8 1.4 1.5 1 1 0 1 1 1 0 Processivity clamp loader gamma complex DNA pol III C-term SHIPPO-rpt PF07004.7 CAM71951.1 - 1.3e-17 63.6 18.3 0.012 16.4 0.0 8.7 8 0 0 8 8 8 7 Sperm-tail PG-rich repeat Arrestin_N PF00339.24 CAM71952.1 - 4.4e-07 29.8 0.0 1.1e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_N PF00339.24 CAM71953.1 - 7.6e-06 25.8 0.1 3.1e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain dsrm PF00035.20 CAM71953.1 - 0.52 10.9 5.2 0.82 10.2 0.0 2.9 3 0 0 3 3 3 0 Double-stranded RNA binding motif HAP2-GCS1 PF10699.4 CAM71954.1 - 1.1e-20 73.3 0.0 2.2e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 Male gamete fusion factor DUF3737 PF12541.3 CAM71954.1 - 0.026 13.5 0.0 3.1 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3737) F-actin_cap_A PF01267.12 CAM71954.1 - 0.36 9.8 0.1 0.59 9.1 0.1 1.2 1 0 0 1 1 1 0 F-actin capping protein alpha subunit Pkinase PF00069.20 CAM71957.1 - 5.4e-53 179.7 0.0 7.5e-33 113.7 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CAM71957.1 - 1.4e-24 86.5 0.1 1.7e-18 66.6 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase EF-hand_6 PF13405.1 CAM71957.1 - 1.4e-07 30.7 0.0 0.012 15.4 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 CAM71957.1 - 9.4e-05 22.4 0.2 0.0015 18.6 0.1 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CAM71957.1 - 0.00043 19.3 0.0 0.19 11.1 0.0 3.0 3 0 0 3 3 3 2 EF hand Kinase-like PF14531.1 CAM71957.1 - 0.0011 18.0 0.0 1.2 7.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 CAM71957.1 - 0.024 13.6 0.0 0.05 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_4 PF12799.2 CAM71958.1 - 6.8e-11 41.5 16.5 2.2e-07 30.3 2.0 5.4 3 2 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM71958.1 - 1.4e-08 34.3 18.0 3.7e-06 26.6 2.8 4.3 2 2 3 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 CAM71958.1 - 0.014 15.3 7.4 2.7 8.3 0.2 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat DUF3079 PF11278.3 CAM71958.1 - 3.5 7.2 2.1 4.9 6.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3079) LRR_4 PF12799.2 CAM71961.2 - 6.8e-07 28.7 0.2 0.0043 16.6 0.0 2.3 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM71961.2 - 0.00043 19.9 0.5 0.0018 17.9 0.2 2.0 1 1 1 2 2 2 2 Leucine rich repeat PIP5K PF01504.13 CAM71964.1 - 1.2e-59 201.4 0.0 1.9e-59 200.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase WD40 PF00400.27 CAM71965.1 - 6.1e-14 51.2 23.6 1.6e-05 24.5 1.0 7.4 8 0 0 8 8 8 5 WD domain, G-beta repeat Snf7 PF03357.16 CAM71966.1 - 2.1e-38 131.3 18.7 2.5e-38 131.1 13.0 1.0 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.7 CAM71966.1 - 0.0019 18.3 5.6 0.0023 18.1 0.5 2.6 1 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein WEMBL PF05701.6 CAM71966.1 - 0.0022 16.5 6.6 0.0028 16.2 4.6 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light CENP-Q PF13094.1 CAM71966.1 - 0.0069 16.4 8.9 0.011 15.7 6.1 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit YfdX PF10938.3 CAM71966.1 - 0.36 10.4 7.8 3.9 7.1 5.1 2.3 1 1 0 1 1 1 0 YfdX protein Astro_capsid PF03115.9 CAM71966.1 - 0.84 7.8 6.7 1 7.5 4.7 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor IncA PF04156.9 CAM71966.1 - 4.3 6.8 12.3 16 4.9 8.5 1.8 1 1 0 1 1 1 0 IncA protein Ribosomal_L18ae PF01775.12 CAM71968.1 - 9.5e-41 138.5 1.7 1.3e-40 138.1 1.2 1.2 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Nup35_RRM_2 PF14605.1 CAM71971.1 - 7.8e-14 51.1 0.0 1.2e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Glyco_hydro_32N PF00251.15 CAM71972.1 - 2.7e-61 207.6 4.3 1e-60 205.6 3.4 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 CAM71972.1 - 2.9e-08 33.9 0.0 1.3e-05 25.5 0.0 2.5 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 C terminal PAN_4 PF14295.1 CAM71972.1 - 0.00068 19.2 3.0 0.00068 19.2 2.1 2.1 2 0 0 2 2 2 1 PAN domain zf-RING_2 PF13639.1 CAM71974.2 - 0.0036 17.0 9.6 0.0036 17.0 6.6 2.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_6 PF14835.1 CAM71974.2 - 0.032 14.0 8.3 0.017 14.8 3.5 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 CAM71974.2 - 0.071 12.8 3.7 0.17 11.6 2.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.1 CAM71974.2 - 0.29 10.8 12.8 0.052 13.2 5.9 2.0 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CAM71974.2 - 0.33 11.0 16.5 0.042 13.8 6.7 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CAM71974.2 - 1.1 8.9 15.5 0.069 12.8 6.2 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CAM71974.2 - 7.1 6.5 14.2 0.11 12.4 4.7 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING TPR_12 PF13424.1 CAM71977.1 - 8e-67 221.1 34.6 2e-14 53.2 1.4 8.1 6 2 2 8 8 8 8 Tetratricopeptide repeat TPR_10 PF13374.1 CAM71977.1 - 2.1e-37 125.9 25.1 2.2e-06 27.3 0.1 11.1 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_11 PF13414.1 CAM71977.1 - 1.9e-28 97.9 39.7 6.8e-07 28.8 2.3 8.2 6 3 3 9 9 9 7 TPR repeat TPR_2 PF07719.12 CAM71977.1 - 2.5e-20 70.7 43.1 0.0025 17.6 0.3 12.4 12 1 0 12 12 12 6 Tetratricopeptide repeat TPR_1 PF00515.23 CAM71977.1 - 1.1e-17 62.8 42.0 0.00011 21.6 0.0 12.0 14 0 0 14 14 13 6 Tetratricopeptide repeat TPR_16 PF13432.1 CAM71977.1 - 3.9e-15 56.0 30.3 0.0012 19.5 1.1 8.6 7 2 1 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.1 CAM71977.1 - 1.7e-14 52.4 21.8 0.00067 19.2 0.1 10.0 10 1 1 11 11 11 4 Tetratricopeptide repeat TPR_8 PF13181.1 CAM71977.1 - 3.7e-13 48.2 30.6 0.021 14.5 0.0 10.6 12 0 0 12 12 12 5 Tetratricopeptide repeat TPR_14 PF13428.1 CAM71977.1 - 6e-12 45.0 29.4 0.58 10.9 0.0 11.5 8 2 3 11 11 11 2 Tetratricopeptide repeat TPR_19 PF14559.1 CAM71977.1 - 4.3e-05 23.7 25.1 0.089 13.1 0.2 7.7 7 1 1 8 8 8 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 CAM71977.1 - 0.016 14.4 0.0 19 4.5 0.0 4.2 3 0 0 3 3 3 0 SHNi-TPR TPR_17 PF13431.1 CAM71977.1 - 0.28 11.5 15.2 33 5.0 0.0 7.7 7 1 0 7 7 7 0 Tetratricopeptide repeat ATP-synt_D PF01813.12 CAM71978.2 - 1.3e-75 253.2 1.0 1.9e-75 252.7 0.7 1.2 1 0 0 1 1 1 1 ATP synthase subunit D Exo_endo_phos PF03372.18 CAM71979.1 - 3.8e-10 40.1 0.1 5.7e-10 39.5 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SET PF00856.23 CAM71981.2 - 3.2e-10 40.5 1.8 0.0052 17.0 0.1 3.5 3 0 0 3 3 3 3 SET domain FHA PF00498.21 CAM71982.2 - 0.054 13.6 0.0 0.15 12.1 0.0 1.8 2 0 0 2 2 2 0 FHA domain PA28_beta PF02252.13 CAM71984.1 - 3.2e-06 26.6 0.0 0.0018 17.7 0.0 2.3 2 0 0 2 2 2 2 Proteasome activator pa28 beta subunit CBS PF00571.23 CAM71985.1 - 3.1e-16 58.8 0.5 0.00012 21.7 0.0 4.3 4 0 0 4 4 4 4 CBS domain RrnaAD PF00398.15 CAM71986.1 - 2.4e-28 98.8 0.0 3e-27 95.3 0.0 1.9 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.7 CAM71986.1 - 0.00037 20.9 0.0 0.00096 19.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 CAM71986.1 - 0.044 13.0 0.0 0.067 12.4 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Actin PF00022.14 CAM71988.1 - 2.3e-57 194.1 0.0 1.5e-47 161.9 0.0 2.0 2 0 0 2 2 2 2 Actin Aminotran_1_2 PF00155.16 CAM71991.1 - 3.9e-67 226.7 0.0 4.4e-67 226.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II FYVE_2 PF02318.11 CAM71991.1 - 0.028 14.3 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger FAD_binding_2 PF00890.19 CAM71992.1 - 5e-84 282.5 0.1 7.8e-84 281.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain ApbE PF02424.10 CAM71992.1 - 1.2e-53 181.9 0.0 2.5e-53 180.9 0.0 1.5 1 0 0 1 1 1 1 ApbE family NAD_binding_1 PF00175.16 CAM71992.1 - 2.4e-16 60.2 0.0 5e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_oxidored PF12831.2 CAM71992.1 - 7.6e-11 41.7 4.9 2.5e-10 40.0 3.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.19 CAM71992.1 - 1.1e-10 40.9 2.0 9e-10 37.9 1.4 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_6 PF00970.19 CAM71992.1 - 2.1e-09 37.3 0.0 4.8e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Pyr_redox_2 PF07992.9 CAM71992.1 - 4.4e-09 36.5 0.2 3.5e-06 27.0 0.3 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CAM71992.1 - 6.3e-07 29.3 2.2 2.5e-06 27.4 1.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 CAM71992.1 - 3.5e-06 26.1 5.7 8.6e-06 24.8 2.9 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 CAM71992.1 - 0.00016 21.8 0.3 0.015 15.3 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CAM71992.1 - 0.00022 19.8 5.1 0.00059 18.4 2.2 2.4 3 0 0 3 3 3 1 HI0933-like protein AlaDh_PNT_C PF01262.16 CAM71992.1 - 0.001 18.6 0.8 0.0031 17.0 0.5 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 CAM71992.1 - 0.0023 18.3 1.5 0.0056 17.0 1.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_6 PF08030.7 CAM71992.1 - 0.0042 16.9 0.0 0.062 13.2 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_3 PF01494.14 CAM71992.1 - 0.075 12.0 1.2 0.12 11.4 0.8 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 CAM71992.1 - 0.19 10.6 1.7 0.35 9.7 1.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein DUF2838 PF10998.3 CAM71994.1 - 4.3e-13 49.1 9.5 1.2e-10 41.2 4.2 4.0 4 1 0 4 4 4 2 Protein of unknown function (DUF2838) PBP1_TM PF14812.1 CAM71995.1 - 0.31 11.3 4.5 0.073 13.3 0.8 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Telomere_reg-2 PF10193.4 CAM71996.1 - 0.069 13.4 0.0 0.72 10.1 0.0 2.6 2 0 0 2 2 2 0 Telomere length regulation protein COX6B PF02297.12 CAM71998.1 - 0.0046 16.9 0.1 0.23 11.4 0.0 2.3 2 0 0 2 2 2 2 Cytochrome oxidase c subunit VIb tRNA-synt_2c PF01411.14 CAM71999.1 - 8.3 4.5 15.6 0.23 9.6 5.4 1.9 1 1 1 2 2 2 0 tRNA synthetases class II (A) DUF2805 PF10985.3 CAM72002.1 - 0.05 13.5 0.3 0.078 12.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2805) DUF4355 PF14265.1 CAM72002.1 - 0.098 12.6 7.4 0.15 12.0 5.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4355) DUF1682 PF07946.9 CAM72002.1 - 0.95 8.2 5.0 1.1 8.0 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PSP1 PF04468.7 CAM72004.1 - 6.3e-27 93.3 0.3 1.3e-26 92.3 0.2 1.6 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Cupin_8 PF13621.1 CAM72005.1 - 0.038 13.4 0.0 0.08 12.4 0.0 1.5 1 0 0 1 1 1 0 Cupin-like domain Aldose_epim PF01263.15 CAM72006.1 - 3.7e-38 131.3 0.0 4.3e-38 131.1 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Pkinase PF00069.20 CAM72009.1 - 3.9e-30 104.8 0.0 4.8e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM72009.1 - 2.3e-12 46.5 0.0 2.5e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CAM72009.1 - 2.1e-06 27.6 0.0 0.0017 18.1 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CAM72009.1 - 0.023 13.7 0.3 0.038 13.0 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family polyprenyl_synt PF00348.12 CAM72009.1 - 0.037 12.8 0.1 0.061 12.1 0.0 1.3 1 0 0 1 1 1 0 Polyprenyl synthetase Pkinase PF00069.20 CAM72010.1 - 2.1e-35 122.1 0.0 2.5e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM72010.1 - 3.9e-13 49.0 0.0 5e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CAM72010.1 - 0.00015 21.6 0.0 0.00044 20.0 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CAM72010.1 - 0.0067 15.5 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CAM72010.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL zf-CCCH PF00642.19 CAM72011.1 - 9.7e-06 25.1 6.2 1.5e-05 24.5 4.3 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Cupin_5 PF06172.6 CAM72012.1 - 7.1e-40 136.1 0.0 6.7e-38 129.7 0.0 2.1 1 1 0 1 1 1 1 Cupin superfamily (DUF985) zf-CCCH PF00642.19 CAM72013.1 - 3.5e-07 29.7 1.0 6.7e-07 28.8 0.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pkinase PF00069.20 CAM72014.1 - 6.5e-65 218.8 0.0 9.2e-65 218.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM72014.1 - 5.1e-22 78.1 0.0 1.2e-21 76.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM72014.1 - 2e-05 23.7 0.1 0.068 12.1 0.1 3.1 2 1 0 3 3 3 2 Kinase-like Kdo PF06293.9 CAM72014.1 - 0.0027 16.8 0.0 0.0053 15.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1966 PF09260.6 CAM72015.1 - 0.15 12.1 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1966) CAF-1_p150 PF11600.3 CAM72016.2 - 0.0013 18.2 2.0 0.0018 17.7 1.4 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Pox_RNA_Pol_19 PF05320.7 CAM72016.2 - 0.14 11.9 0.8 0.23 11.2 0.5 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Nucleoplasmin PF03066.10 CAM72016.2 - 0.61 9.5 2.2 1.2 8.6 1.5 1.4 1 0 0 1 1 1 0 Nucleoplasmin CDC45 PF02724.9 CAM72016.2 - 1.2 7.0 4.9 1.8 6.5 3.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Kri1 PF05178.7 CAM72017.1 - 8.8e-23 80.4 9.3 8.8e-23 80.4 6.5 3.9 4 0 0 4 4 4 1 KRI1-like family Kri1_C PF12936.2 CAM72017.1 - 4.4e-22 77.8 0.0 2.7e-21 75.3 0.0 2.4 1 0 0 1 1 1 1 KRI1-like family C-terminal Peptidase_M15_3 PF08291.6 CAM72018.1 - 0.085 12.6 0.0 0.27 11.0 0.0 1.8 1 0 0 1 1 1 0 Peptidase M15 Rdx PF10262.4 CAM72019.1 - 7.4e-08 32.3 0.0 1.5e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Rdx family STT3 PF02516.9 CAM72021.1 - 3.9e-52 177.8 33.4 3.9e-49 167.9 21.3 2.2 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit STT3 PF02516.9 CAM72022.1 - 3e-50 171.6 27.2 3.9e-47 161.3 17.0 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PMT PF02366.13 CAM72022.1 - 7.5e-06 25.4 10.3 7.5e-06 25.4 7.1 2.0 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase VirB8 PF04335.8 CAM72022.1 - 0.12 11.9 0.3 0.4 10.2 0.2 1.9 1 0 0 1 1 1 0 VirB8 protein STT3 PF02516.9 CAM72023.1 - 1.4e-45 156.1 30.6 2.7e-45 155.2 21.2 1.4 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Rhodanese PF00581.15 CAM72025.1 - 3.5e-10 40.2 0.0 7.1e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain FAD_binding_2 PF00890.19 CAM72026.1 - 1.4e-84 284.3 0.1 2.1e-84 283.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain ApbE PF02424.10 CAM72026.1 - 2.6e-67 226.7 0.0 4e-67 226.1 0.0 1.3 1 0 0 1 1 1 1 ApbE family NAD_binding_1 PF00175.16 CAM72026.1 - 2.2e-17 63.5 0.0 5.7e-17 62.2 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_oxidored PF12831.2 CAM72026.1 - 1.6e-12 47.2 1.4 3.6e-12 46.0 0.9 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 CAM72026.1 - 6.9e-11 41.6 2.5 2.7e-08 33.1 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CAM72026.1 - 2.3e-08 34.1 1.6 1.7e-06 28.0 1.1 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_6 PF00970.19 CAM72026.1 - 7.6e-08 32.3 0.0 1.7e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_8 PF13450.1 CAM72026.1 - 2.1e-07 30.8 1.5 1.2e-06 28.4 0.7 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 CAM72026.1 - 2.3e-07 30.0 6.3 1.5e-06 27.3 1.5 2.7 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_6 PF08030.7 CAM72026.1 - 2e-06 27.8 0.0 0.0024 17.8 0.0 2.5 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Pyr_redox PF00070.22 CAM72026.1 - 1.7e-05 25.1 1.9 7.1e-05 23.1 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CAM72026.1 - 2e-05 23.2 4.7 0.00011 20.8 1.2 2.6 3 0 0 3 3 3 1 HI0933-like protein AlaDh_PNT_C PF01262.16 CAM72026.1 - 0.0011 18.5 0.3 0.0027 17.3 0.2 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 CAM72026.1 - 0.0015 17.6 0.3 0.0026 16.8 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 CAM72026.1 - 0.0032 17.5 2.4 0.4 10.6 0.2 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CAM72026.1 - 0.004 16.2 1.6 0.012 14.7 0.3 2.4 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 CAM72026.1 - 0.0046 15.9 1.7 0.012 14.5 0.5 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 CAM72027.1 - 7.3e-91 305.0 0.6 8.3e-91 304.8 0.4 1.0 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 CAM72027.1 - 4.2e-09 36.5 1.2 6.7e-06 26.1 0.1 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CAM72027.1 - 6.5e-09 35.3 2.6 8.7e-09 34.9 1.3 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.19 CAM72027.1 - 2.1e-08 33.4 7.5 2e-07 30.2 5.1 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CAM72027.1 - 4.3e-08 33.0 1.6 1.6e-07 31.2 0.9 2.2 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CAM72027.1 - 5.3e-07 29.9 0.5 2.2e-05 24.6 0.3 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CAM72027.1 - 0.00042 18.8 8.4 0.0027 16.2 0.4 3.4 4 0 0 4 4 4 2 HI0933-like protein GIDA PF01134.17 CAM72027.1 - 0.00059 18.8 13.3 0.00087 18.2 2.6 3.0 3 0 0 3 3 3 2 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 CAM72027.1 - 0.0041 16.7 0.4 0.0085 15.6 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 CAM72027.1 - 0.0079 15.1 1.1 0.16 10.8 0.3 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 CAM72027.1 - 0.012 14.7 0.7 0.02 13.9 0.5 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 CAM72027.1 - 0.022 15.1 2.4 0.053 13.9 0.7 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 CAM72027.1 - 0.1 12.5 0.3 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 TrkA-N domain Thi4 PF01946.12 CAM72027.1 - 0.12 11.4 3.8 0.048 12.7 0.7 1.7 2 0 0 2 2 2 0 Thi4 family HA2 PF04408.18 CAM72028.1 - 9.3e-23 80.1 0.0 2e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CAM72028.1 - 1.2e-17 63.7 0.0 2.6e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CAM72028.1 - 3.9e-15 55.4 0.0 1e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAM72028.1 - 1.1e-08 34.7 0.1 3.9e-08 32.9 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CAM72028.1 - 1.6e-06 28.3 0.0 3.6e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 CAM72028.1 - 0.00051 19.0 0.0 0.001 18.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 CAM72028.1 - 0.015 15.0 0.0 0.04 13.6 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 CAM72028.1 - 0.019 15.2 0.1 0.11 12.7 0.1 2.2 1 1 0 1 1 1 0 ABC transporter ResIII PF04851.10 CAM72028.1 - 0.038 13.8 0.0 8 6.2 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.1 CAM72028.1 - 0.059 13.4 0.0 0.43 10.6 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_29 PF13555.1 CAM72028.1 - 0.069 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRP54 PF00448.17 CAM72028.1 - 0.074 12.4 0.0 0.15 11.4 0.0 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Sigma54_activat PF00158.21 CAM72028.1 - 0.14 11.6 0.0 1.1 8.7 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain Armet PF10208.4 CAM72029.1 - 5.1e-09 35.9 0.0 9.5e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding SAP PF02037.22 CAM72029.1 - 3.5e-05 23.1 0.6 6.7e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 SAP domain DUF4554 PF15091.1 CAM72029.1 - 0.047 12.4 0.3 8.6 4.9 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4554) adh_short PF00106.20 CAM72030.1 - 9.5e-27 93.9 0.1 1.9e-26 93.0 0.2 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 CAM72030.1 - 5.7e-15 55.7 0.7 7.9e-15 55.2 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CAM72030.1 - 3.2e-11 43.2 0.1 4.1e-11 42.8 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CAM72030.1 - 3.7e-05 23.8 0.1 4.9e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CAM72030.1 - 0.0022 17.4 0.6 0.0037 16.7 0.4 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF871 PF05913.6 CAM72030.1 - 0.0032 16.3 0.1 0.0044 15.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF871) Polysacc_synt_2 PF02719.10 CAM72030.1 - 0.024 13.5 1.2 0.037 12.9 0.8 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein TIR-like PF10137.4 CAM72030.1 - 0.075 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain adh_short PF00106.20 CAM72031.1 - 3.3e-19 69.4 0.5 1.7e-18 67.0 0.3 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CAM72031.1 - 1.5e-07 31.4 0.0 2.1e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CAM72031.1 - 2.6e-06 27.2 0.0 4.9e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CAM72031.1 - 2.1e-05 24.1 0.0 3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CAM72031.1 - 0.0042 17.1 0.7 0.041 13.8 0.5 2.0 1 1 0 1 1 1 1 NADH(P)-binding DFP PF04127.10 CAM72031.1 - 0.027 14.0 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein HrcA_DNA-bdg PF03444.10 CAM72032.1 - 0.2 11.1 1.4 12 5.3 0.1 3.4 3 0 0 3 3 3 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Glutaredoxin PF00462.19 CAM72033.1 - 3.3e-16 59.0 1.0 2.8e-12 46.4 0.0 3.2 3 0 0 3 3 3 2 Glutaredoxin Thioredoxin PF00085.15 CAM72033.1 - 1.6e-13 50.2 0.1 3.7e-13 49.0 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 CAM72033.1 - 0.00019 21.4 0.0 0.00046 20.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.1 CAM72033.1 - 0.00065 19.6 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.1 CAM72033.1 - 0.051 13.3 0.1 0.65 9.8 0.1 2.2 2 0 0 2 2 2 0 Thioredoxin domain AhpC-TSA PF00578.16 CAM72033.1 - 0.059 13.0 0.0 0.099 12.3 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_2 PF13098.1 CAM72033.1 - 0.088 13.0 0.1 0.13 12.4 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain AAA PF00004.24 CAM72034.1 - 6.3e-36 123.4 0.0 1.4e-35 122.3 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CAM72034.1 - 5.2e-08 33.7 0.1 1.7e-07 32.1 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 CAM72034.1 - 8e-08 32.1 0.0 1.9e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CAM72034.1 - 1.3e-07 31.7 0.1 5.6e-06 26.4 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 CAM72034.1 - 7.1e-07 28.5 0.0 1.9e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CAM72034.1 - 1.4e-06 28.4 0.0 0.00034 20.7 0.0 2.5 1 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 CAM72034.1 - 1.9e-06 26.9 0.0 8.4e-06 24.7 0.0 2.0 1 1 0 2 2 2 1 TIP49 C-terminus AAA_33 PF13671.1 CAM72034.1 - 6.9e-06 25.9 0.0 1.6e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CAM72034.1 - 1.7e-05 25.0 0.0 3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CAM72034.1 - 6e-05 22.2 0.0 0.00015 20.9 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_14 PF13173.1 CAM72034.1 - 0.00012 22.0 0.0 0.00021 21.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CAM72034.1 - 0.00018 20.9 0.0 0.00033 20.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 CAM72034.1 - 0.00027 20.6 0.4 0.002 17.8 0.2 2.4 1 1 0 1 1 1 1 Part of AAA domain SKI PF01202.17 CAM72034.1 - 0.00028 20.8 0.0 0.0016 18.3 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase RNA_helicase PF00910.17 CAM72034.1 - 0.00037 20.6 0.0 0.00076 19.6 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.1 CAM72034.1 - 0.0014 18.6 0.1 0.0035 17.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 CAM72034.1 - 0.0026 16.9 0.0 0.005 16.0 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 CAM72034.1 - 0.0035 17.4 0.0 0.01 15.9 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_24 PF13479.1 CAM72034.1 - 0.0041 16.7 0.1 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 CAM72034.1 - 0.0041 16.7 0.0 0.0091 15.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 CAM72034.1 - 0.0043 16.4 1.1 0.069 12.5 0.1 2.3 1 1 1 2 2 2 1 AAA domain NACHT PF05729.7 CAM72034.1 - 0.0059 16.2 0.0 0.016 14.8 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_2 PF07724.9 CAM72034.1 - 0.0069 16.3 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.21 CAM72034.1 - 0.009 15.4 0.0 0.027 13.9 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain Parvo_NS1 PF01057.12 CAM72034.1 - 0.017 14.0 0.0 0.032 13.1 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 CAM72034.1 - 0.022 14.3 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 CAM72034.1 - 0.022 14.3 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 CAM72034.1 - 0.029 13.9 0.0 0.072 12.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PhoH PF02562.11 CAM72034.1 - 0.029 13.5 0.0 0.057 12.6 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein DUF815 PF05673.8 CAM72034.1 - 0.03 13.2 0.0 0.078 11.8 0.0 1.9 2 1 0 2 2 1 0 Protein of unknown function (DUF815) Rad17 PF03215.10 CAM72034.1 - 0.044 12.4 0.0 0.061 11.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF2075 PF09848.4 CAM72034.1 - 0.052 12.5 0.0 0.074 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 CAM72034.1 - 0.061 13.6 0.1 1.3 9.3 0.0 2.4 1 1 1 2 2 2 0 ABC transporter PPV_E1_C PF00519.12 CAM72034.1 - 0.076 11.6 0.0 0.12 10.9 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase ResIII PF04851.10 CAM72034.1 - 0.084 12.6 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AFG1_ATPase PF03969.11 CAM72034.1 - 0.11 11.2 0.3 0.29 9.9 0.0 1.6 1 1 0 2 2 2 0 AFG1-like ATPase 2OG-FeII_Oxy_2 PF13532.1 CAM72036.1 - 1.2e-11 44.8 0.0 1.9e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 CAM72036.1 - 4.7e-06 26.8 0.0 6.7e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily FCD PF07729.7 CAM72037.1 - 0.015 15.6 0.8 3.4 8.0 0.0 2.4 2 0 0 2 2 2 0 FCD domain UQ_con PF00179.21 CAM72038.1 - 1.3e-53 180.2 0.0 1.4e-53 180.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CAM72038.1 - 0.002 18.0 0.0 0.0022 17.8 0.0 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 CAM72038.1 - 0.0039 16.9 0.0 0.0048 16.6 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 CAM72038.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 UEV domain Histone PF00125.19 CAM72039.1 - 8e-14 51.5 0.9 9.7e-14 51.2 0.6 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 CAM72039.1 - 0.00025 20.9 0.1 0.0004 20.2 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 CAM72039.1 - 0.00056 19.9 0.1 0.00056 19.9 0.1 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CAM72039.1 - 0.0016 18.1 0.0 0.0021 17.7 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 CAM72039.1 - 0.0041 16.8 0.0 0.0043 16.8 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit FbpA PF05833.6 CAM72039.1 - 0.036 12.5 0.0 0.043 12.3 0.0 1.0 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) PCP_red PF08369.5 CAM72039.1 - 0.051 13.4 0.9 0.1 12.5 0.2 1.9 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit DUF4400 PF14348.1 CAM72039.1 - 0.16 11.3 0.3 0.23 10.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) Thioredoxin PF00085.15 CAM72041.1 - 3.4e-14 52.3 0.2 1.3e-13 50.5 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 CAM72041.1 - 0.0036 17.4 0.1 0.022 14.9 0.1 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CAM72041.1 - 0.019 15.0 0.1 0.16 12.1 0.1 2.7 2 1 0 2 2 2 0 Thioredoxin-like Thioredoxin_6 PF13848.1 CAM72041.1 - 0.036 13.8 0.1 4.4 7.0 0.0 2.6 2 1 0 2 2 2 0 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CAM72041.1 - 0.079 12.9 0.0 0.33 11.0 0.0 2.1 1 0 0 1 1 1 0 Thioredoxin-like zf-CDGSH PF09360.5 CAM72044.1 - 4e-26 90.5 9.6 1.8e-14 53.2 1.4 2.2 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type Peptidase_M16 PF00675.15 CAM72045.1 - 4.2e-28 97.9 0.0 7e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CAM72045.1 - 3.1e-16 59.5 0.0 9.4e-16 58.0 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain CRS1_YhbY PF01985.16 CAM72045.1 - 0.087 12.8 0.1 3.8 7.5 0.0 2.6 2 0 0 2 2 2 0 CRS1 / YhbY (CRM) domain OTU PF02338.14 CAM72046.1 - 9.1e-15 55.3 0.1 1.7e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease zf-RanBP PF00641.13 CAM72046.1 - 6.8e-06 25.0 1.6 6.8e-06 25.0 1.1 5.1 4 1 1 5 5 5 2 Zn-finger in Ran binding protein and others Peptidase_C65 PF10275.4 CAM72046.1 - 9.6e-05 21.8 0.0 0.3 10.3 0.0 2.2 1 1 1 2 2 2 2 Peptidase C65 Otubain RRN7 PF11781.3 CAM72046.1 - 0.0031 16.9 1.5 0.0031 16.9 1.1 3.7 4 1 1 5 5 5 1 RNA polymerase I-specific transcription initiation factor Rrn7 zf-tcix PF14952.1 CAM72046.1 - 0.033 13.5 0.3 0.033 13.5 0.2 3.7 3 1 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding DZR PF12773.2 CAM72046.1 - 0.045 13.5 30.6 0.062 13.1 4.7 3.7 3 1 0 3 3 3 0 Double zinc ribbon zf-ribbon_3 PF13248.1 CAM72046.1 - 2.7 7.3 20.5 0.16 11.2 0.5 3.6 3 0 0 3 3 3 0 zinc-ribbon domain Auto_anti-p27 PF06677.7 CAM72046.1 - 6.1 6.6 9.3 20 5.0 0.3 3.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) RRM_1 PF00076.17 CAM72047.1 - 1.5e-06 27.7 0.0 0.064 12.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM72047.1 - 3.4e-05 23.7 0.0 9.4e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM72047.1 - 3.9e-05 23.4 0.3 0.00027 20.7 0.0 2.4 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF572 PF04502.8 CAM72047.1 - 0.13 11.5 8.3 0.16 11.1 5.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) SRP-alpha_N PF04086.8 CAM72047.1 - 0.57 9.5 9.5 0.72 9.1 6.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal tRNA-synt_2b PF00587.20 CAM72048.1 - 7.3e-44 149.3 0.0 1.4e-43 148.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CAM72048.1 - 8.6e-17 60.8 0.2 1.8e-16 59.8 0.2 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 CAM72048.1 - 8.9e-14 51.0 0.0 2.9e-13 49.4 0.0 1.9 2 0 0 2 2 2 1 TGS domain tRNA_SAD PF07973.9 CAM72048.1 - 3.6e-11 42.7 0.0 6.1e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TPR_11 PF13414.1 CAM72049.1 - 1.5e-25 88.6 12.5 2.7e-11 42.9 0.6 5.4 2 2 3 5 5 5 5 TPR repeat TPR_1 PF00515.23 CAM72049.1 - 9.7e-23 78.7 5.0 1.5e-06 27.5 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 CAM72049.1 - 1.1e-21 76.9 10.6 1.3e-09 38.4 0.3 5.5 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 CAM72049.1 - 1.2e-20 71.7 7.4 1.7e-05 24.3 0.0 6.7 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 CAM72049.1 - 6.5e-20 69.6 7.8 2.9e-05 23.9 0.6 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 CAM72049.1 - 4.4e-15 55.3 1.9 1e-07 31.7 0.0 3.9 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 CAM72049.1 - 1.1e-13 50.5 22.4 5.1e-05 23.5 0.1 7.8 4 3 5 9 9 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 CAM72049.1 - 6.5e-12 45.6 13.3 5.2e-06 26.6 0.1 5.2 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 CAM72049.1 - 3e-10 39.1 3.8 0.017 14.8 0.0 6.4 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 CAM72049.1 - 1e-09 37.4 0.4 0.37 10.6 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_20 PF14561.1 CAM72049.1 - 0.0011 19.0 14.6 1.2 9.2 0.1 5.5 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 CAM72049.1 - 0.0011 18.7 8.4 1.8 8.6 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 CAM72049.1 - 0.0073 16.6 18.5 0.87 10.1 0.0 6.9 8 1 0 8 8 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 CAM72049.1 - 0.0099 15.7 11.4 0.21 11.4 0.1 4.1 4 1 0 5 5 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CAM72049.1 - 0.26 11.1 3.4 5.2 7.0 0.1 4.2 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat Ribosomal_L2_C PF03947.13 CAM72050.1 - 5.4e-40 136.1 2.2 6.2e-40 136.0 0.8 1.6 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CAM72050.1 - 4.6e-13 48.9 0.0 1.5e-12 47.2 0.0 1.9 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Ribosomal_L2_C PF03947.13 CAM72051.1 - 5.4e-40 136.1 2.2 6.2e-40 136.0 0.8 1.6 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CAM72051.1 - 4.6e-13 48.9 0.0 1.5e-12 47.2 0.0 1.9 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain TPR_MLP1_2 PF07926.7 CAM72052.1 - 0.02 14.6 0.0 0.02 14.6 0.0 6.7 5 1 2 7 7 7 0 TPR/MLP1/MLP2-like protein Methyltransf_23 PF13489.1 CAM72062.1 - 3.1e-18 66.0 0.0 1.1e-17 64.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CAM72062.1 - 3.8e-13 49.7 0.0 7.6e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CAM72062.1 - 1.2e-09 37.6 0.0 1.5e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 CAM72062.1 - 8e-08 32.6 0.0 2.4e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAM72062.1 - 5.8e-07 29.2 0.0 9.5e-07 28.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CAM72062.1 - 3.1e-05 23.9 0.0 0.00011 22.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAM72062.1 - 4.3e-05 23.8 0.0 8.9e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAM72062.1 - 0.0034 17.9 0.0 0.0061 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain AsnC_trans_reg PF01037.16 CAM72062.1 - 0.014 15.0 0.2 0.15 11.7 0.0 2.2 2 0 0 2 2 2 0 AsnC family MTS PF05175.9 CAM72062.1 - 0.076 12.3 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Arginase PF00491.16 CAM72063.1 - 1.7e-73 247.3 0.0 2e-73 247.1 0.0 1.0 1 0 0 1 1 1 1 Arginase family Choline_kinase PF01633.15 CAM72064.1 - 2.8e-31 108.7 0.1 1.3e-30 106.5 0.1 2.0 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CAM72064.1 - 3.1e-11 43.4 0.0 2.4e-08 33.9 0.0 2.6 2 1 0 2 2 2 2 Phosphotransferase enzyme family NIF PF03031.13 CAM72066.1 - 6.3e-18 64.9 0.0 1.2e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase zf-CCCH PF00642.19 CAM72066.1 - 5.8e-07 29.0 1.1 1.1e-06 28.1 0.8 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Zip PF02535.17 CAM72066.1 - 0.2 10.5 1.9 3.1 6.7 0.0 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter DUF4381 PF14316.1 CAM72067.1 - 2 8.5 8.6 17 5.5 4.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Rieske PF00355.21 CAM72069.2 - 5.1e-15 54.8 0.0 8.7e-15 54.0 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Methyltransf_23 PF13489.1 CAM72072.1 - 5.2e-18 65.2 0.0 1.8e-17 63.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CAM72072.1 - 5e-13 49.3 0.0 1.1e-12 48.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CAM72072.1 - 1.7e-09 37.1 0.0 2.3e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 CAM72072.1 - 8.9e-08 32.5 0.0 3.4e-07 30.6 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAM72072.1 - 8.2e-07 28.7 0.0 1.4e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CAM72072.1 - 2.9e-05 24.0 0.0 0.00016 21.7 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAM72072.1 - 5.9e-05 23.3 0.0 0.00012 22.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAM72072.1 - 0.0039 17.7 0.0 0.0087 16.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain AsnC_trans_reg PF01037.16 CAM72072.1 - 0.021 14.4 0.2 0.19 11.4 0.0 2.2 2 0 0 2 2 2 0 AsnC family MTS PF05175.9 CAM72072.1 - 0.094 12.0 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Peptidase_C14 PF00656.17 CAM72073.1 - 1.1e-48 166.1 0.0 1.4e-48 165.8 0.0 1.1 1 0 0 1 1 1 1 Caspase domain DUF1664 PF07889.7 CAM72074.1 - 0.12 12.1 1.3 0.34 10.7 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) EF-hand_7 PF13499.1 CAM72078.1 - 0.00064 19.8 0.0 0.0017 18.4 0.0 1.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CAM72078.1 - 0.0089 15.2 0.0 4.7 6.7 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CAM72078.1 - 0.02 14.7 0.0 2.8 8.0 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain Cortex-I_coil PF09304.5 CAM72080.1 - 0.0081 16.1 13.0 0.0081 16.1 9.0 6.9 2 2 4 6 6 6 2 Cortexillin I, coiled coil MutL_C PF08676.6 CAM72081.1 - 2.4e-27 95.2 0.0 5.3e-27 94.1 0.0 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 CAM72081.1 - 1.8e-09 37.0 0.0 3.3e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 CAM72081.1 - 1.9e-07 30.7 0.5 1.4e-06 28.0 0.1 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CAM72081.1 - 3.3e-07 29.9 0.1 1e-06 28.4 0.1 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase KOW PF00467.24 CAM72082.1 - 1.2e-06 28.0 0.7 3.5e-06 26.4 0.5 1.9 1 1 0 1 1 1 1 KOW motif LRR_4 PF12799.2 CAM72084.1 - 6.5e-12 44.7 3.5 3.3e-06 26.5 1.9 3.6 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM72084.1 - 2.8e-09 36.5 7.3 6.2e-07 29.0 2.5 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 CAM72084.1 - 4.6e-07 28.9 5.5 6.1 7.2 0.1 5.5 4 1 1 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 CAM72084.1 - 4e-05 23.1 6.7 21 5.8 0.3 5.7 5 0 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 CAM72084.1 - 7.6e-05 22.3 1.7 1.4 9.2 0.2 4.9 5 0 0 5 5 5 1 Leucine Rich repeat FlaC_arch PF05377.6 CAM72084.1 - 0.018 14.8 0.4 0.064 13.1 0.1 1.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DivIVA PF05103.8 CAM72084.1 - 0.02 14.9 2.1 0.02 14.9 1.5 2.9 2 1 1 3 3 3 0 DivIVA protein Macoilin PF09726.4 CAM72084.1 - 0.36 9.0 14.7 0.46 8.6 10.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Takusan PF04822.8 CAM72084.1 - 0.73 9.6 7.5 0.032 13.9 1.1 1.9 2 0 0 2 2 2 0 Takusan IncA PF04156.9 CAM72084.1 - 0.82 9.2 19.6 1.6 8.2 13.5 1.6 1 1 0 1 1 1 0 IncA protein Reo_sigmaC PF04582.7 CAM72084.1 - 1.2 8.2 6.6 3 6.9 0.9 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Sec2p PF06428.6 CAM72084.1 - 2.3 8.1 16.8 1.1 9.1 1.2 3.0 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p RTC PF01137.16 CAM72085.1 - 1.2e-52 178.0 0.1 1.3e-52 177.8 0.1 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 CAM72085.1 - 3.8e-25 87.8 0.1 6e-25 87.2 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Pro_isomerase PF00160.16 CAM72086.1 - 2.3e-13 50.6 0.0 3.6e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.20 CAM72087.1 - 7e-56 189.2 0.0 8.2e-56 189.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM72087.1 - 3.3e-18 65.7 0.0 6.1e-18 64.8 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CAM72087.1 - 7.9e-06 25.7 0.0 0.00034 20.4 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CAM72087.1 - 0.02 13.8 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like UCH PF00443.24 CAM72088.1 - 1.2e-52 178.7 0.5 2e-52 177.9 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CAM72088.1 - 5.7e-25 88.3 0.1 1.1e-24 87.3 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.3 CAM72088.1 - 2.6e-12 46.5 0.0 1.5e-10 40.7 0.0 2.7 3 0 0 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 CAM72088.1 - 9.9e-11 41.4 0.2 2.8e-07 30.1 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-specific protease C-terminal Robl_LC7 PF03259.12 CAM72089.1 - 1.5e-20 72.5 0.0 1.9e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Roadblock/LC7 domain Epimerase_2 PF02350.14 CAM72089.1 - 0.0011 17.8 0.6 0.0012 17.7 0.1 1.3 2 0 0 2 2 2 1 UDP-N-acetylglucosamine 2-epimerase DUF3800 PF12686.2 CAM72089.1 - 0.066 12.8 0.0 0.068 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3800) DUF1422 PF07226.6 CAM72090.1 - 0.067 12.9 0.5 0.1 12.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1422) DUF4307 PF14155.1 CAM72090.1 - 0.089 12.5 0.2 0.13 12.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) Proteasom_Rpn13 PF04683.8 CAM72091.1 - 1.8e-18 66.3 0.3 2.8e-18 65.7 0.2 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor DUF972 PF06156.8 CAM72092.1 - 0.037 14.3 1.9 0.037 14.3 1.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) APG6 PF04111.7 CAM72092.1 - 0.17 10.9 5.3 0.21 10.5 3.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1367 PF07105.6 CAM72092.1 - 0.28 10.5 2.2 6.7 6.0 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1367) CR6_interact PF10147.4 CAM72092.1 - 0.31 10.3 8.2 0.44 9.8 5.7 1.3 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 CENP-H PF05837.7 CAM72092.1 - 0.43 10.7 8.9 0.13 12.4 1.1 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) FUSC PF04632.7 CAM72092.1 - 2.8 6.2 5.5 4.7 5.5 3.8 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4570 PF15134.1 CAM72092.1 - 3.3 7.5 9.0 0.37 10.6 1.6 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4570) DivIC PF04977.10 CAM72092.1 - 5.8 6.4 9.2 0.35 10.3 0.6 2.3 2 0 0 2 2 2 0 Septum formation initiator DNA_pol_E_B PF04042.11 CAM72093.1 - 3.7e-21 75.3 0.0 5.7e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DTW PF03942.10 CAM72094.2 - 6.1e-28 97.4 0.0 1.1e-27 96.5 0.0 1.4 1 0 0 1 1 1 1 DTW domain C1_4 PF07975.7 CAM72094.2 - 0.054 13.5 0.5 0.11 12.4 0.4 1.5 1 0 0 1 1 1 0 TFIIH C1-like domain zf-RING_3 PF14369.1 CAM72094.2 - 0.29 11.1 4.8 1.8 8.6 0.3 2.5 1 1 1 2 2 2 0 zinc-finger GAS PF13851.1 CAM72095.1 - 6e-62 208.4 26.8 6e-62 208.4 18.6 3.2 2 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding DUF2365 PF10157.4 CAM72095.1 - 0.013 15.4 3.5 0.33 10.8 0.1 3.1 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2365) DUF948 PF06103.6 CAM72095.1 - 0.27 11.1 18.8 0.45 10.4 0.2 5.4 1 1 5 7 7 7 0 Bacterial protein of unknown function (DUF948) DinB_2 PF12867.2 CAM72095.1 - 1.8 8.9 9.9 0.54 10.6 1.9 3.4 3 1 0 3 3 3 0 DinB superfamily Ebp2 PF05890.7 CAM72096.1 - 8.9e-57 192.4 13.7 1.6e-56 191.6 9.5 1.3 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 GvpL_GvpF PF06386.6 CAM72096.1 - 0.3 10.6 9.8 0.1 12.1 3.3 2.2 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF EMP24_GP25L PF01105.19 CAM72099.1 - 5.1e-41 140.3 0.1 6.1e-41 140.1 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD MogR_DNAbind PF12181.3 CAM72099.1 - 0.012 15.3 0.6 0.018 14.7 0.4 1.2 1 0 0 1 1 1 0 DNA binding domain of the motility gene repressor (MogR) Cation_ATPase_C PF00689.16 CAM72099.1 - 0.59 9.6 3.3 4.9 6.6 0.0 2.5 3 0 0 3 3 3 0 Cation transporting ATPase, C-terminus Pkinase PF00069.20 CAM72100.1 - 2.8e-54 184.0 0.0 3.5e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM72100.1 - 1.3e-21 76.8 0.0 2.6e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 CAM72100.1 - 0.094 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 CAM72100.1 - 0.11 11.8 0.1 0.39 10.0 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL SH3BP5 PF05276.9 CAM72101.1 - 0.0057 15.9 0.3 0.0092 15.3 0.2 1.2 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) GAF_2 PF13185.1 CAM72101.1 - 0.015 15.8 0.2 0.15 12.5 0.0 2.8 3 1 1 4 4 4 0 GAF domain Ribosomal_L18p PF00861.17 CAM72103.1 - 4.2e-38 130.1 0.6 4.2e-38 130.1 0.4 1.9 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 CAM72103.1 - 2.7e-23 82.3 4.7 2.7e-23 82.3 3.3 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L36e PF01158.13 CAM72105.1 - 7.5e-34 115.6 1.8 9.1e-34 115.3 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e PHD PF00628.24 CAM72107.1 - 0.0018 17.8 1.8 0.0018 17.8 1.3 1.9 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.1 CAM72107.1 - 0.093 12.4 6.4 0.21 11.3 4.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 C1_1 PF00130.17 CAM72107.1 - 0.16 11.7 10.7 0.06 13.0 4.5 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1423 PF07227.6 CAM72107.1 - 1.3 7.5 5.4 2.3 6.7 3.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1423) UPF0184 PF03670.8 CAM72108.1 - 0.032 14.4 1.0 0.088 12.9 0.7 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) DUF2205 PF10224.4 CAM72108.1 - 0.62 9.6 4.3 0.35 10.4 0.9 2.0 1 1 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) NYD-SP28_assoc PF14775.1 CAM72108.1 - 1 9.0 8.7 0.81 9.4 1.1 2.4 2 0 0 2 2 2 0 Sperm tail C-terminal domain Cep57_CLD_2 PF14197.1 CAM72108.1 - 2 8.3 17.1 0.13 12.2 5.6 2.4 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Rho_Binding PF08912.6 CAM72108.1 - 2.2 8.6 6.5 4 7.8 4.5 1.4 1 0 0 1 1 1 0 Rho Binding DivIC PF04977.10 CAM72108.1 - 2.5 7.6 6.5 17 4.9 1.1 2.3 2 0 0 2 2 2 0 Septum formation initiator Atg14 PF10186.4 CAM72108.1 - 3.9 6.3 12.8 6.6 5.5 8.9 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 CAM72108.1 - 9.5 5.7 10.9 16 5.0 7.5 1.3 1 0 0 1 1 1 0 IncA protein ATP11 PF06644.6 CAM72109.1 - 7.7e-24 84.6 0.3 9.4e-24 84.3 0.2 1.1 1 0 0 1 1 1 1 ATP11 protein Lysine_decarbox PF03641.9 CAM72110.1 - 2.4e-15 56.5 0.4 8e-15 54.8 0.0 1.8 1 1 1 2 2 2 1 Possible lysine decarboxylase UBX PF00789.15 CAM72111.1 - 1.1e-06 28.5 0.1 5.3e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 UBX domain Milton PF12448.3 CAM72111.1 - 0.031 14.4 3.5 0.061 13.5 2.4 1.5 1 0 0 1 1 1 0 Kinesin associated protein Thioredoxin_7 PF13899.1 CAM72111.1 - 0.039 13.9 1.4 0.26 11.3 0.0 2.8 3 0 0 3 3 3 0 Thioredoxin-like CAF-1_p150 PF11600.3 CAM72111.1 - 1.4 8.2 25.2 2.2 7.6 17.5 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Asp-B-Hydro_N PF05279.6 CAM72111.1 - 1.8 8.3 14.8 2.6 7.8 10.2 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Spore_coat_CotO PF14153.1 CAM72111.1 - 4.3 6.7 8.2 5.7 6.3 4.7 2.0 2 0 0 2 2 2 0 Spore coat protein CotO Trypsin_2 PF13365.1 CAM72112.1 - 0.0032 17.4 0.0 0.0053 16.7 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF658 PF04936.7 CAM72112.1 - 0.016 15.0 0.1 0.85 9.4 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF658) U3_assoc_6 PF08640.6 CAM72113.2 - 2.6e-18 65.5 0.4 2.6e-17 62.3 0.1 2.5 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 Ribosomal_S6e PF01092.14 CAM72115.1 - 2.9e-39 133.6 0.2 5.5e-39 132.7 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e WSK PF03832.8 CAM72115.1 - 0.032 13.5 0.3 0.032 13.5 0.2 1.9 2 0 0 2 2 2 0 WSK motif RdRP_3 PF00998.18 CAM72115.1 - 0.066 11.7 6.0 0.078 11.4 4.2 1.1 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase RmlD_sub_bind PF04321.12 CAM72116.1 - 2.6e-05 23.2 0.0 0.034 13.0 0.0 2.3 2 0 0 2 2 2 2 RmlD substrate binding domain NAD_binding_10 PF13460.1 CAM72116.1 - 0.0005 20.1 0.0 0.00088 19.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CAM72116.1 - 0.0059 16.0 0.0 0.016 14.6 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family EF-hand_6 PF13405.1 CAM72117.1 - 1.5e-08 33.8 0.0 0.18 11.8 0.1 3.8 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.27 CAM72117.1 - 1.1e-07 30.5 0.0 0.21 10.9 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 CAM72117.1 - 4.8e-06 26.6 0.0 0.4 10.8 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.1 CAM72117.1 - 0.012 15.1 0.3 2.2 7.9 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_5 PF13202.1 CAM72117.1 - 0.073 12.4 0.0 1.7 8.1 0.1 2.5 2 0 0 2 2 2 0 EF hand Ank_2 PF12796.2 CAM72118.1 - 3.1e-69 229.3 34.5 1e-10 41.8 0.1 14.5 9 3 8 17 17 17 13 Ankyrin repeats (3 copies) Ank PF00023.25 CAM72118.1 - 4.3e-44 146.1 62.1 2.3e-05 23.9 0.3 20.8 21 0 0 21 21 21 13 Ankyrin repeat Ank_4 PF13637.1 CAM72118.1 - 3.1e-34 116.7 29.2 4e-05 23.9 0.0 15.3 13 3 2 16 16 16 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 CAM72118.1 - 1.1e-33 111.9 38.4 0.0047 17.0 0.1 20.2 21 0 0 21 21 21 11 Ankyrin repeat Ank_5 PF13857.1 CAM72118.1 - 5.7e-30 102.6 68.3 1.1e-07 31.7 0.4 19.6 16 5 6 22 22 22 7 Ankyrin repeats (many copies) Filamin PF00630.14 CAM72118.1 - 0.0017 18.9 0.0 0.021 15.3 0.0 2.5 2 0 0 2 2 2 1 Filamin/ABP280 repeat DUF2454 PF10521.4 CAM72118.1 - 0.43 9.5 0.0 2.6 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2454) Ribosomal_L32e PF01655.13 CAM72119.1 - 1.3e-40 137.8 0.5 1.6e-40 137.6 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 SH3_9 PF14604.1 CAM72120.1 - 5e-34 115.6 1.6 2.8e-13 49.2 0.0 4.9 5 0 0 5 5 5 3 Variant SH3 domain SH3_1 PF00018.23 CAM72120.1 - 3.3e-29 100.0 0.1 4.6e-12 45.1 0.0 3.5 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.12 CAM72120.1 - 4.7e-25 86.8 0.8 6.4e-12 44.7 0.1 3.8 4 0 0 4 4 4 3 Variant SH3 domain DUF4205 PF13898.1 CAM72121.1 - 2.3e-25 89.0 0.0 4.2e-25 88.2 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4205) E1-E2_ATPase PF00122.15 CAM72122.1 - 1.2e-61 207.7 1.8 2.6e-61 206.5 1.2 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CAM72122.1 - 6.2e-29 100.8 2.7 6.2e-29 100.8 1.9 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CAM72122.1 - 4.7e-25 89.2 0.0 1.7e-24 87.4 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CAM72122.1 - 4.4e-15 55.4 0.0 1e-14 54.2 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CAM72122.1 - 3.2e-10 39.2 0.0 7.4e-10 38.1 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CAM72122.1 - 3.3e-10 40.4 0.0 2e-09 37.8 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CAM72122.1 - 1.4e-05 24.7 2.5 3.1e-05 23.6 0.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3671 PF12420.3 CAM72122.1 - 5.6 6.9 6.5 0.33 10.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function Kinesin PF00225.18 CAM72123.1 - 2.8e-73 246.5 0.0 6.1e-43 146.7 0.0 2.2 2 0 0 2 2 2 2 Kinesin motor domain DUF106 PF01956.11 CAM72124.2 - 0.071 12.6 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Integral membrane protein DUF106 SlyX PF04102.7 CAM72124.2 - 1.9 8.8 6.2 0.85 10.0 0.5 3.1 3 0 0 3 3 3 0 SlyX Dpy-30 PF05186.8 CAM72125.1 - 6.3 6.3 6.6 53 3.4 0.1 3.8 4 0 0 4 4 4 0 Dpy-30 motif KMP11 PF03037.11 CAM72128.1 - 6.1e-55 183.7 18.1 6.8e-55 183.6 12.5 1.0 1 0 0 1 1 1 1 Kinetoplastid membrane protein 11 Apolipoprotein PF01442.13 CAM72128.1 - 0.0079 15.7 5.3 0.028 13.9 3.7 1.7 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Lyase_8_N PF08124.6 CAM72128.1 - 0.043 12.6 2.5 0.045 12.6 1.8 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain Herpes_BLRF2 PF05812.7 CAM72128.1 - 0.076 12.8 2.4 0.094 12.5 1.6 1.2 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein Psb28 PF03912.9 CAM72128.1 - 0.082 12.8 1.5 0.1 12.5 0.8 1.3 1 1 0 1 1 1 0 Psb28 protein Brr6_like_C_C PF10104.4 CAM72128.1 - 0.086 12.3 1.2 0.095 12.2 0.8 1.1 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain FdsD PF11390.3 CAM72128.1 - 0.11 12.5 2.2 0.31 11.1 1.5 1.9 1 1 0 1 1 1 0 NADH-dependant formate dehydrogenase delta subunit FdsD FCH PF00611.18 CAM72128.1 - 0.13 12.5 5.4 0.097 12.8 0.9 2.0 1 1 1 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain NYD-SP28 PF14772.1 CAM72128.1 - 0.15 12.1 9.4 1.6 8.8 0.3 2.5 2 1 0 2 2 2 0 Sperm tail DUF4404 PF14357.1 CAM72128.1 - 0.16 12.3 4.2 1.1 9.7 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) T5orf172 PF10544.4 CAM72128.1 - 0.18 12.2 2.6 0.2 12.0 1.8 1.2 1 0 0 1 1 1 0 T5orf172 domain Metal_resist PF13801.1 CAM72128.1 - 0.22 11.5 2.6 0.55 10.2 0.1 2.0 1 1 1 2 2 2 0 Heavy-metal resistance ARL2_Bind_BART PF11527.3 CAM72128.1 - 0.24 11.1 10.3 0.32 10.7 6.9 1.4 1 1 0 1 1 1 0 The ARF-like 2 binding protein BART INCENP_N PF12178.3 CAM72128.1 - 0.33 10.5 2.4 9.9 5.8 0.1 2.6 2 1 1 3 3 3 0 Chromosome passenger complex (CPC) protein INCENP N terminal DUF3994 PF13159.1 CAM72128.1 - 0.74 10.1 4.9 0.31 11.3 1.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3994) DUF2884 PF11101.3 CAM72128.1 - 0.75 9.1 9.7 2.2 7.6 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) DUF922 PF06037.6 CAM72128.1 - 0.85 8.9 6.7 0.34 10.2 3.0 1.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF922) DUF3417 PF11897.3 CAM72128.1 - 0.96 9.4 5.1 9.1 6.2 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3417) TipAS PF07739.8 CAM72128.1 - 1.2 9.4 11.4 0.79 10.0 2.8 2.0 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain DUF148 PF02520.12 CAM72128.1 - 1.2 8.8 9.1 11 5.9 4.3 2.2 1 1 1 2 2 2 0 Domain of unknown function DUF148 Phage_GPO PF05929.6 CAM72128.1 - 1.8 7.7 5.6 2 7.5 3.9 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Vps54 PF07928.7 CAM72128.1 - 2 8.5 4.2 2.5 8.2 1.4 1.8 2 0 0 2 2 2 0 Vps54-like protein YtxH PF12732.2 CAM72128.1 - 2.4 8.6 5.2 10 6.5 3.6 1.9 1 1 0 1 1 1 0 YtxH-like protein Mitofilin PF09731.4 CAM72128.1 - 2.7 6.5 11.3 3.3 6.2 7.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PWWP PF00855.12 CAM72128.1 - 3.9 7.7 7.0 6.5 7.0 4.9 1.4 1 1 0 1 1 1 0 PWWP domain YlqD PF11068.3 CAM72128.1 - 7.5 6.6 9.1 20 5.2 6.3 1.6 1 1 0 1 1 1 0 YlqD protein KMP11 PF03037.11 CAM72129.1 - 6.9e-57 190.0 17.2 7.6e-57 189.9 11.9 1.0 1 0 0 1 1 1 1 Kinetoplastid membrane protein 11 Apolipoprotein PF01442.13 CAM72129.1 - 0.0079 15.7 5.0 0.027 13.9 3.5 1.7 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Lyase_8_N PF08124.6 CAM72129.1 - 0.025 13.4 1.9 0.026 13.4 1.3 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain Brr6_like_C_C PF10104.4 CAM72129.1 - 0.068 12.6 0.7 0.076 12.5 0.5 1.1 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain FdsD PF11390.3 CAM72129.1 - 0.074 13.1 1.5 0.2 11.8 1.1 1.8 1 1 0 1 1 1 0 NADH-dependant formate dehydrogenase delta subunit FdsD Herpes_BLRF2 PF05812.7 CAM72129.1 - 0.075 12.8 2.2 0.092 12.5 1.5 1.2 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein Psb28 PF03912.9 CAM72129.1 - 0.082 12.8 1.4 0.1 12.5 1.0 1.3 1 1 0 1 1 1 0 Psb28 protein DUF3584 PF12128.3 CAM72129.1 - 0.089 10.1 6.9 0.1 9.9 4.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NYD-SP28 PF14772.1 CAM72129.1 - 0.1 12.6 8.4 1.6 8.8 0.3 2.5 2 1 0 2 2 2 0 Sperm tail FCH PF00611.18 CAM72129.1 - 0.16 12.1 4.8 0.15 12.2 1.2 1.9 1 1 1 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain GrpE PF01025.14 CAM72129.1 - 0.19 11.2 5.7 0.22 11.0 3.9 1.2 1 0 0 1 1 1 0 GrpE ARL2_Bind_BART PF11527.3 CAM72129.1 - 0.22 11.3 9.2 0.35 10.6 6.2 1.4 1 1 0 1 1 1 0 The ARF-like 2 binding protein BART Metal_resist PF13801.1 CAM72129.1 - 0.22 11.4 2.5 0.67 9.9 0.2 2.0 1 1 1 2 2 2 0 Heavy-metal resistance DUF4404 PF14357.1 CAM72129.1 - 0.23 11.8 4.8 1.2 9.6 0.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) T5orf172 PF10544.4 CAM72129.1 - 0.26 11.7 2.9 0.31 11.4 2.0 1.2 1 0 0 1 1 1 0 T5orf172 domain INCENP_N PF12178.3 CAM72129.1 - 0.34 10.4 2.4 9.9 5.8 0.1 2.5 2 1 1 3 3 3 0 Chromosome passenger complex (CPC) protein INCENP N terminal DUF2884 PF11101.3 CAM72129.1 - 0.61 9.4 9.1 2.1 7.6 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) DUF3994 PF13159.1 CAM72129.1 - 0.72 10.1 4.1 0.4 10.9 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3994) DUF3417 PF11897.3 CAM72129.1 - 1.1 9.2 5.6 8.7 6.3 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3417) Phage_GPO PF05929.6 CAM72129.1 - 1.1 8.4 4.5 1.2 8.3 3.1 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF922 PF06037.6 CAM72129.1 - 1.2 8.4 6.7 0.54 9.5 2.8 1.5 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF922) TipAS PF07739.8 CAM72129.1 - 1.7 9.0 11.2 1.1 9.6 2.6 2.0 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain YtxH PF12732.2 CAM72129.1 - 1.7 9.0 4.6 0.8 10.1 0.6 1.9 1 1 1 2 2 2 0 YtxH-like protein DUF148 PF02520.12 CAM72129.1 - 1.8 8.3 8.3 16 5.2 3.7 2.3 1 1 1 2 2 2 0 Domain of unknown function DUF148 Vps54 PF07928.7 CAM72129.1 - 2 8.5 4.2 2.5 8.2 1.4 1.8 2 0 0 2 2 2 0 Vps54-like protein Mitofilin PF09731.4 CAM72129.1 - 2.6 6.6 10.6 3.3 6.2 7.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PWWP PF00855.12 CAM72129.1 - 3.7 7.8 6.9 6.1 7.1 4.8 1.4 1 1 0 1 1 1 0 PWWP domain Vma12 PF11712.3 CAM72129.1 - 7 6.3 9.0 1.3 8.7 1.8 2.1 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase YlqD PF11068.3 CAM72129.1 - 8.6 6.4 8.3 23 5.0 5.7 1.6 1 1 0 1 1 1 0 YlqD protein KMP11 PF03037.11 CAM72130.1 - 6.9e-57 190.0 17.2 7.6e-57 189.9 11.9 1.0 1 0 0 1 1 1 1 Kinetoplastid membrane protein 11 Apolipoprotein PF01442.13 CAM72130.1 - 0.0079 15.7 5.0 0.027 13.9 3.5 1.7 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Lyase_8_N PF08124.6 CAM72130.1 - 0.025 13.4 1.9 0.026 13.4 1.3 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain Brr6_like_C_C PF10104.4 CAM72130.1 - 0.068 12.6 0.7 0.076 12.5 0.5 1.1 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain FdsD PF11390.3 CAM72130.1 - 0.074 13.1 1.5 0.2 11.8 1.1 1.8 1 1 0 1 1 1 0 NADH-dependant formate dehydrogenase delta subunit FdsD Herpes_BLRF2 PF05812.7 CAM72130.1 - 0.075 12.8 2.2 0.092 12.5 1.5 1.2 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein Psb28 PF03912.9 CAM72130.1 - 0.082 12.8 1.4 0.1 12.5 1.0 1.3 1 1 0 1 1 1 0 Psb28 protein DUF3584 PF12128.3 CAM72130.1 - 0.089 10.1 6.9 0.1 9.9 4.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NYD-SP28 PF14772.1 CAM72130.1 - 0.1 12.6 8.4 1.6 8.8 0.3 2.5 2 1 0 2 2 2 0 Sperm tail FCH PF00611.18 CAM72130.1 - 0.16 12.1 4.8 0.15 12.2 1.2 1.9 1 1 1 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain GrpE PF01025.14 CAM72130.1 - 0.19 11.2 5.7 0.22 11.0 3.9 1.2 1 0 0 1 1 1 0 GrpE ARL2_Bind_BART PF11527.3 CAM72130.1 - 0.22 11.3 9.2 0.35 10.6 6.2 1.4 1 1 0 1 1 1 0 The ARF-like 2 binding protein BART Metal_resist PF13801.1 CAM72130.1 - 0.22 11.4 2.5 0.67 9.9 0.2 2.0 1 1 1 2 2 2 0 Heavy-metal resistance DUF4404 PF14357.1 CAM72130.1 - 0.23 11.8 4.8 1.2 9.6 0.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) T5orf172 PF10544.4 CAM72130.1 - 0.26 11.7 2.9 0.31 11.4 2.0 1.2 1 0 0 1 1 1 0 T5orf172 domain INCENP_N PF12178.3 CAM72130.1 - 0.34 10.4 2.4 9.9 5.8 0.1 2.5 2 1 1 3 3 3 0 Chromosome passenger complex (CPC) protein INCENP N terminal DUF2884 PF11101.3 CAM72130.1 - 0.61 9.4 9.1 2.1 7.6 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) DUF3994 PF13159.1 CAM72130.1 - 0.72 10.1 4.1 0.4 10.9 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3994) DUF3417 PF11897.3 CAM72130.1 - 1.1 9.2 5.6 8.7 6.3 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3417) Phage_GPO PF05929.6 CAM72130.1 - 1.1 8.4 4.5 1.2 8.3 3.1 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF922 PF06037.6 CAM72130.1 - 1.2 8.4 6.7 0.54 9.5 2.8 1.5 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF922) TipAS PF07739.8 CAM72130.1 - 1.7 9.0 11.2 1.1 9.6 2.6 2.0 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain YtxH PF12732.2 CAM72130.1 - 1.7 9.0 4.6 0.8 10.1 0.6 1.9 1 1 1 2 2 2 0 YtxH-like protein DUF148 PF02520.12 CAM72130.1 - 1.8 8.3 8.3 16 5.2 3.7 2.3 1 1 1 2 2 2 0 Domain of unknown function DUF148 Vps54 PF07928.7 CAM72130.1 - 2 8.5 4.2 2.5 8.2 1.4 1.8 2 0 0 2 2 2 0 Vps54-like protein Mitofilin PF09731.4 CAM72130.1 - 2.6 6.6 10.6 3.3 6.2 7.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PWWP PF00855.12 CAM72130.1 - 3.7 7.8 6.9 6.1 7.1 4.8 1.4 1 1 0 1 1 1 0 PWWP domain Vma12 PF11712.3 CAM72130.1 - 7 6.3 9.0 1.3 8.7 1.8 2.1 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase YlqD PF11068.3 CAM72130.1 - 8.6 6.4 8.3 23 5.0 5.7 1.6 1 1 0 1 1 1 0 YlqD protein ATG_C PF09333.6 CAM72133.1 - 0.026 14.6 0.1 0.55 10.4 0.1 2.7 1 1 0 1 1 1 0 ATG C terminal domain ATP-grasp_4 PF13535.1 CAM72134.1 - 2.5e-25 89.2 0.1 2.5e-24 86.0 0.1 2.2 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CAM72134.1 - 1.4e-07 30.6 0.0 0.0019 17.0 0.0 2.5 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 CAM72134.1 - 0.0028 17.5 0.0 0.028 14.2 0.0 2.3 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 CAM72134.1 - 0.073 12.3 0.0 5.2 6.3 0.0 2.2 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.14 CAM72134.1 - 0.14 11.6 0.0 0.88 9.0 0.0 2.0 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Helicase_C PF00271.26 CAM72135.1 - 1.7e-07 31.0 0.0 3.7e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAM72135.1 - 7e-05 22.3 0.0 0.00017 21.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CAM72135.1 - 0.13 12.3 0.0 0.39 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.20 CAM72140.1 - 4.1e-42 144.1 0.2 2e-24 86.1 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAM72140.1 - 4.6e-26 91.4 0.0 1.9e-22 79.6 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CAM72140.1 - 2.6e-06 26.6 0.0 0.0046 15.9 0.0 2.3 2 0 0 2 2 2 2 Kinase-like RNA_pol_Rpb1_3 PF04983.13 CAM72140.1 - 0.072 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 3 Pox_ser-thr_kin PF05445.6 CAM72140.1 - 0.1 11.3 0.1 0.16 10.7 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase HEAT_EZ PF13513.1 CAM72141.1 - 1.8e-06 28.2 6.7 0.058 13.8 0.0 6.4 5 1 0 5 5 5 2 HEAT-like repeat HEAT PF02985.17 CAM72141.1 - 0.00016 21.4 6.4 20 5.5 0.1 7.2 6 0 0 6 6 6 1 HEAT repeat 2Fe-2S_thioredx PF01257.14 CAM72141.1 - 0.00031 20.3 0.0 0.00077 19.0 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin IBN_N PF03810.14 CAM72141.1 - 0.011 15.6 2.2 0.061 13.2 0.7 2.6 2 0 0 2 2 2 0 Importin-beta N-terminal domain Ipi1_N PF12333.3 CAM72141.1 - 0.069 13.1 0.9 3 7.8 0.1 3.5 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation Adaptin_N PF01602.15 CAM72141.1 - 0.14 10.4 0.0 0.29 9.4 0.0 1.4 1 0 0 1 1 1 0 Adaptin N terminal region CAF1 PF04857.15 CAM72142.1 - 1.4e-23 83.5 0.0 1.6e-15 57.1 0.0 2.2 2 0 0 2 2 2 2 CAF1 family ribonuclease Peptidase_M24 PF00557.19 CAM72143.1 - 8.6e-50 169.1 0.6 1.3e-49 168.5 0.4 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 CAM72143.1 - 1.2e-30 105.6 0.0 2e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain EGF PF00008.22 CAM72143.1 - 0.2 11.6 3.1 0.43 10.5 2.2 1.5 1 0 0 1 1 1 0 EGF-like domain AT_hook PF02178.14 CAM72144.1 - 2.9 7.8 26.1 0.35 10.6 4.6 4.2 3 1 0 3 3 3 0 AT hook motif NIF PF03031.13 CAM72145.1 - 1.6e-27 96.1 0.1 2.7e-27 95.3 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 CAM72145.1 - 0.005 17.0 0.4 0.0071 16.5 0.3 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase zf-HC5HC2H PF13771.1 CAM72146.1 - 2.5e-06 27.5 9.0 2.5e-06 27.5 6.2 2.2 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 CAM72146.1 - 0.0033 17.3 9.8 0.0033 17.3 6.8 2.4 2 1 0 2 2 2 1 PHD-zinc-finger like domain TruD PF01142.13 CAM72147.1 - 5e-06 25.4 0.0 0.089 11.4 0.0 2.6 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Ank PF00023.25 CAM72150.1 - 2.6e-29 99.5 3.6 4.8e-13 48.1 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 CAM72150.1 - 2.4e-25 88.6 3.5 3.5e-17 62.5 0.3 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CAM72150.1 - 6.7e-25 86.5 9.2 1.4e-09 37.9 0.3 3.7 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 CAM72150.1 - 2e-22 79.1 3.0 2.1e-10 40.8 0.2 3.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CAM72150.1 - 3.1e-22 76.4 0.9 3e-08 33.1 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat HSBP1 PF06825.7 CAM72151.1 - 1.7e-25 88.3 4.7 2e-25 88.1 3.3 1.0 1 0 0 1 1 1 1 Heat shock factor binding protein 1 DUF2884 PF11101.3 CAM72151.1 - 0.0027 17.1 1.2 0.0028 17.0 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2884) SF-assemblin PF06705.6 CAM72151.1 - 0.003 16.7 0.5 0.0036 16.4 0.4 1.0 1 0 0 1 1 1 1 SF-assemblin/beta giardin Matrilin_ccoil PF10393.4 CAM72151.1 - 0.011 15.0 0.1 2.5 7.5 0.0 2.4 1 1 1 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin HR1 PF02185.11 CAM72151.1 - 0.017 14.8 0.7 0.17 11.6 0.1 1.9 1 1 0 2 2 2 0 Hr1 repeat TPR_MLP1_2 PF07926.7 CAM72151.1 - 0.018 14.7 0.0 0.023 14.4 0.0 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein BLOC1_2 PF10046.4 CAM72151.1 - 0.018 15.1 0.3 0.023 14.8 0.2 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF241 PF03087.9 CAM72151.1 - 0.028 13.9 0.2 0.029 13.8 0.1 1.0 1 0 0 1 1 1 0 Arabidopsis protein of unknown function Cytochrom_B562 PF07361.6 CAM72151.1 - 0.031 14.7 1.0 0.036 14.4 0.7 1.1 1 0 0 1 1 1 0 Cytochrome b562 Apolipoprotein PF01442.13 CAM72151.1 - 0.031 13.7 0.2 0.036 13.5 0.1 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain FtsK_SpoIIIE PF01580.13 CAM72151.1 - 0.032 13.7 0.0 0.035 13.5 0.0 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family Phage_GPO PF05929.6 CAM72151.1 - 0.034 13.3 0.4 0.036 13.3 0.3 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Transposase_22 PF02994.9 CAM72151.1 - 0.038 12.4 0.2 0.041 12.3 0.1 1.1 1 0 0 1 1 1 0 L1 transposable element Hemagglutinin PF00509.13 CAM72151.1 - 0.038 12.1 0.1 0.042 12.0 0.1 1.0 1 0 0 1 1 1 0 Haemagglutinin YvrJ PF12841.2 CAM72151.1 - 0.039 13.2 0.2 0.83 8.9 0.1 2.2 1 1 1 2 2 2 0 YvrJ protein family DUF4618 PF15397.1 CAM72151.1 - 0.043 13.1 0.2 0.049 12.9 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) SseC PF04888.7 CAM72151.1 - 0.053 12.8 0.4 0.056 12.7 0.3 1.0 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Allexi_40kDa PF05549.6 CAM72151.1 - 0.054 12.7 0.4 0.06 12.6 0.3 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein DHC_N1 PF08385.7 CAM72151.1 - 0.056 11.8 0.0 0.062 11.6 0.0 1.0 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 UPF0184 PF03670.8 CAM72151.1 - 0.094 12.9 0.5 0.15 12.2 0.3 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) HalX PF08663.5 CAM72151.1 - 0.1 12.5 1.1 0.64 10.0 0.8 2.0 1 1 0 1 1 1 0 HalX domain DUF2130 PF09903.4 CAM72151.1 - 0.11 11.2 0.4 0.12 11.1 0.2 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) DUF4351 PF14261.1 CAM72151.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4351) Erythro-docking PF09277.6 CAM72151.1 - 0.13 11.9 0.1 1.3 8.7 0.0 2.1 1 1 1 2 2 2 0 Erythronolide synthase, docking Baculo_PEP_C PF04513.7 CAM72151.1 - 0.13 12.0 0.1 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Nsp1_C PF05064.8 CAM72151.1 - 0.13 11.8 0.5 0.16 11.6 0.3 1.1 1 0 0 1 1 1 0 Nsp1-like C-terminal region NPV_P10 PF05531.7 CAM72151.1 - 0.14 12.4 0.6 0.41 10.9 0.4 1.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein MtrB PF05440.7 CAM72151.1 - 0.18 11.8 0.4 0.25 11.4 0.3 1.3 1 1 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B GvpK PF05121.7 CAM72151.1 - 0.19 11.5 0.9 0.25 11.1 0.6 1.2 1 0 0 1 1 1 0 Gas vesicle protein K HSCB_C PF07743.8 CAM72151.1 - 0.59 10.6 3.7 1.9 8.9 2.5 1.8 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain BTB_2 PF02214.17 CAM72152.1 - 5.3e-12 45.7 0.0 2.1e-11 43.8 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Rabaptin PF03528.10 CAM72152.1 - 0.26 11.2 2.1 0.53 10.2 1.4 1.5 1 0 0 1 1 1 0 Rabaptin TRAPPC9-Trs120 PF08626.6 CAM72153.1 - 7.4e-07 26.9 0.0 6e-05 20.6 0.0 3.1 3 1 0 3 3 3 3 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit SNARE PF05739.14 CAM72155.1 - 1.2e-19 69.7 0.6 1.2e-19 69.7 0.4 2.5 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 CAM72155.1 - 0.00032 20.8 11.9 0.0028 17.7 1.3 2.6 1 1 2 3 3 3 2 Syntaxin Mitofilin PF09731.4 CAM72155.1 - 0.011 14.4 4.9 0.013 14.1 3.4 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Lipoprotein_6 PF01441.14 CAM72155.1 - 0.017 14.9 1.3 0.12 12.2 0.1 2.2 2 0 0 2 2 2 0 Lipoprotein MutS_III PF05192.13 CAM72155.1 - 0.076 12.7 0.3 0.076 12.7 0.2 2.0 2 1 0 2 2 2 0 MutS domain III Fe_hyd_lg_C PF02906.9 CAM72155.1 - 0.078 12.2 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain Acyl-CoA_dh_1 PF00441.19 CAM72157.1 - 1.4e-41 142.0 3.0 2e-41 141.5 2.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CAM72157.1 - 1.2e-23 83.7 0.0 3e-23 82.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 CAM72157.1 - 1.6e-20 73.7 0.0 2.5e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CAM72157.1 - 2.7e-19 68.4 0.3 8.7e-19 66.7 0.3 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain GalKase_gal_bdg PF10509.4 CAM72158.1 - 4.2e-18 64.3 0.0 1.1e-17 62.9 0.0 1.8 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 CAM72158.1 - 7.4e-09 35.6 1.9 1.7e-08 34.5 0.0 2.4 2 1 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 CAM72158.1 - 1.3e-08 34.7 0.1 2.6e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain RE_Alw26IDE PF09665.5 CAM72159.1 - 0.55 8.8 12.3 0.53 8.9 7.7 1.5 1 1 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) DUF501 PF04417.7 CAM72159.1 - 1.5 8.6 21.3 2.7 7.8 6.8 3.7 1 1 3 4 4 4 0 Protein of unknown function (DUF501) IncA PF04156.9 CAM72159.1 - 5.3 6.6 49.9 16 5.0 0.1 3.7 2 1 2 4 4 4 0 IncA protein TMPIT PF07851.8 CAM72159.1 - 6.7 5.6 20.7 0.091 11.8 5.1 3.1 2 1 1 3 3 3 0 TMPIT-like protein MMR_HSR1 PF01926.18 CAM72160.1 - 0.00022 21.1 0.0 0.00046 20.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CAM72160.1 - 0.003 16.8 0.0 0.0087 15.3 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.1 CAM72160.1 - 0.0096 16.0 0.0 0.27 11.3 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 CAM72160.1 - 0.024 14.6 1.5 0.087 12.7 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain Arch_ATPase PF01637.13 CAM72160.1 - 0.04 13.6 0.1 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 Archaeal ATPase Miro PF08477.8 CAM72160.1 - 0.15 12.5 0.0 0.63 10.5 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein MFS_1 PF07690.11 CAM72162.1 - 3.6e-28 98.2 41.1 1.8e-22 79.5 11.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CAM72162.1 - 5.3e-11 41.7 12.2 5.3e-11 41.7 8.4 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter Abhydrolase_6 PF12697.2 CAM72164.2 - 2.5e-06 27.5 0.1 7.6e-06 25.9 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CAM72164.2 - 1.7e-05 24.6 0.0 3.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF818 PF05677.7 CAM72164.2 - 5.9e-05 21.9 0.0 8e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_1 PF00561.15 CAM72164.2 - 0.00031 20.3 0.0 0.00049 19.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CAM72164.2 - 0.00031 20.0 0.0 0.00045 19.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.4 CAM72164.2 - 0.028 13.6 0.1 0.047 12.9 0.1 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Lipase_3 PF01764.20 CAM72164.2 - 0.031 13.8 0.0 0.057 13.0 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF2305 PF10230.4 CAM72164.2 - 0.032 13.6 0.1 0.49 9.7 0.0 2.1 1 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_3 PF07859.8 CAM72164.2 - 0.054 13.0 0.1 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold UPF0227 PF05728.7 CAM72164.2 - 0.13 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) SET PF00856.23 CAM72165.1 - 3.1e-07 30.8 0.0 3.1e-05 24.3 0.0 2.9 2 1 0 2 2 2 1 SET domain IATP PF04568.7 CAM72166.1 - 3.3 7.7 4.9 41 4.2 0.1 2.9 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Spt4 PF06093.8 CAM72167.1 - 1.2e-09 37.9 0.0 1.5e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Basic PF01586.11 CAM72167.1 - 0.14 12.8 1.4 0.18 12.5 0.1 1.8 2 0 0 2 2 2 0 Myogenic Basic domain WD40 PF00400.27 CAM72168.2 - 1.2e-05 24.9 4.1 0.011 15.5 0.0 4.1 5 0 0 5 5 5 2 WD domain, G-beta repeat PQQ_2 PF13360.1 CAM72168.2 - 8.4e-05 22.1 0.3 0.0004 19.9 0.1 2.3 2 0 0 2 2 2 1 PQQ-like domain LRR_6 PF13516.1 CAM72168.2 - 0.029 14.4 0.2 6.6 7.1 0.0 3.1 2 0 0 2 2 2 0 Leucine Rich repeat Hira PF07569.6 CAM72168.2 - 0.23 10.6 0.0 0.45 9.6 0.0 1.4 1 0 0 1 1 1 0 TUP1-like enhancer of split UCH PF00443.24 CAM72169.1 - 1.5e-41 142.2 0.0 1.3e-40 139.2 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CAM72169.1 - 7e-11 42.1 0.0 1.2e-08 34.7 0.0 3.0 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Vps5 PF09325.5 CAM72170.1 - 2.5e-17 62.9 6.3 3.5e-17 62.4 4.4 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 CAM72170.1 - 6.3e-16 58.1 0.0 1.3e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.4 CAM72170.1 - 0.018 14.3 1.1 0.061 12.5 0.8 1.8 1 1 0 1 1 1 0 WASP-binding domain of Sorting nexin protein FTCD_C PF04961.7 CAM72170.1 - 0.042 13.2 0.3 0.084 12.2 0.2 1.4 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase DUF4164 PF13747.1 CAM72170.1 - 0.18 11.9 5.5 0.32 11.1 0.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) FAA_hydrolase PF01557.13 CAM72172.1 - 4e-40 137.6 0.1 2e-39 135.3 0.1 1.8 1 1 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF3490 PF11995.3 CAM72172.1 - 8.9e-05 22.1 0.0 0.00029 20.4 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3490) HECT PF00632.20 CAM72173.2 - 2.7e-89 299.4 0.0 5.7e-89 298.3 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WWE PF02825.15 CAM72173.2 - 0.0044 16.4 0.4 0.011 15.1 0.2 1.7 1 0 0 1 1 1 1 WWE domain Ribosomal_L31 PF01197.13 CAM72173.2 - 0.077 13.0 0.1 0.22 11.5 0.0 1.8 1 0 0 1 1 1 0 Ribosomal protein L31 DUF3492 PF11997.3 CAM72174.1 - 0.17 11.3 0.0 0.17 11.3 0.0 2.1 2 2 0 2 2 2 0 Domain of unknown function (DUF3492) Nop53 PF07767.6 CAM72175.1 - 2.5e-10 39.9 18.3 4.5e-09 35.7 12.7 2.3 1 1 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF2346 PF09803.4 CAM72175.1 - 0.31 10.9 0.2 0.31 10.9 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2346) Cystatin PF00031.16 CAM72175.1 - 1.5 9.0 8.5 0.084 13.0 0.4 2.5 2 1 0 2 2 2 0 Cystatin domain GAS PF13851.1 CAM72176.1 - 0.25 10.4 22.2 0.35 10.0 11.0 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Med10 PF09748.4 CAM72176.1 - 0.4 10.5 1.9 1.1 9.0 1.3 1.7 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex ERM PF00769.14 CAM72176.1 - 0.96 8.9 28.7 2.1 7.8 19.9 1.5 1 0 0 1 1 1 0 Ezrin/radixin/moesin family SPX PF03105.14 CAM72176.1 - 2 8.1 3.7 0.85 9.3 0.7 1.7 2 0 0 2 2 2 0 SPX domain CorA PF01544.13 CAM72176.1 - 7.9 5.4 6.3 15 4.4 4.4 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF1675 PF07897.6 CAM72176.1 - 9.6 5.9 8.7 21 4.8 6.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Yos1 PF08571.5 CAM72178.1 - 2.4e-31 107.6 0.3 3.5e-31 107.1 0.2 1.2 1 0 0 1 1 1 1 Yos1-like zf-RING_2 PF13639.1 CAM72179.1 - 2.4e-15 56.0 11.9 5.8e-07 29.2 0.1 3.4 3 0 0 3 3 3 2 Ring finger domain zf-RING_5 PF14634.1 CAM72179.1 - 4.7e-08 32.6 2.7 0.0003 20.4 0.2 3.9 3 2 0 3 3 3 2 zinc-RING finger domain zf-rbx1 PF12678.2 CAM72179.1 - 5.8e-06 26.3 8.7 0.031 14.3 0.1 3.8 3 1 1 4 4 4 2 RING-H2 zinc finger IQ PF00612.22 CAM72179.1 - 6.7e-05 22.1 1.7 0.00031 20.1 1.2 2.3 1 0 0 1 1 1 1 IQ calmodulin-binding motif zf-C3HC4_3 PF13920.1 CAM72179.1 - 9e-05 22.0 4.0 0.0017 17.9 0.4 3.6 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAM72179.1 - 0.00031 20.6 19.0 0.0037 17.2 0.7 3.9 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) DUF1010 PF06231.6 CAM72180.1 - 0.037 14.0 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1010) DctQ PF04290.7 CAM72181.1 - 6.9 6.4 14.0 0.42 10.3 5.8 1.8 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component SUR7 PF06687.7 CAM72181.1 - 8.3 5.9 9.7 0.37 10.3 2.7 1.8 2 0 0 2 2 2 0 SUR7/PalI family RRM_1 PF00076.17 CAM72182.1 - 1.6e-15 56.4 0.0 2.8e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM72182.1 - 5.4e-12 45.5 0.0 8.1e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM72182.1 - 0.038 13.8 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_1 PF00667.15 CAM72183.2 - 5.8e-32 110.9 0.0 9.6e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CAM72183.2 - 1.8e-16 60.4 0.3 4.9e-12 46.0 0.0 3.0 3 0 0 3 3 3 2 Flavodoxin FAD_binding_6 PF00970.19 CAM72183.2 - 3.1e-05 24.0 0.0 9.4e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 CAM72183.2 - 0.00024 21.6 0.0 0.0045 17.5 0.0 2.4 1 1 1 2 2 2 1 Oxidoreductase NAD-binding domain Cortex-I_coil PF09304.5 CAM72184.1 - 0.0078 16.2 1.7 0.014 15.4 1.2 1.4 1 0 0 1 1 1 1 Cortexillin I, coiled coil IncA PF04156.9 CAM72184.1 - 0.11 12.0 2.2 0.18 11.3 1.5 1.3 1 0 0 1 1 1 0 IncA protein DUF2561 PF10812.3 CAM72185.1 - 0.028 14.0 1.1 0.049 13.2 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) CcoS PF03597.10 CAM72185.1 - 0.037 13.4 0.5 0.068 12.6 0.4 1.3 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type zf-DHHC PF01529.15 CAM72186.1 - 1.4e-26 92.9 6.8 1.4e-26 92.9 4.7 1.7 1 1 1 2 2 2 1 DHHC palmitoyltransferase PTP_N PF12453.3 CAM72186.1 - 0.049 13.2 3.4 0.1 12.2 2.3 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase N terminal DUF4491 PF14898.1 CAM72186.1 - 0.49 10.5 5.6 2.3 8.4 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4491) Transgly_assoc PF04226.8 CAM72186.1 - 0.58 10.2 9.3 0.55 10.3 0.8 2.5 2 0 0 2 2 2 0 Transglycosylase associated protein DUF4149 PF13664.1 CAM72186.1 - 2 8.5 8.8 1.8 8.6 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) MFS_1 PF07690.11 CAM72188.1 - 1.4e-25 89.7 28.6 1.1e-20 73.6 10.9 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 CAM72189.1 - 1.3e-23 83.3 32.5 1.6e-19 69.8 4.9 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CAM72189.1 - 3.8e-06 25.7 3.1 3.8e-06 25.7 2.1 2.4 3 0 0 3 3 3 2 Sugar (and other) transporter Leo1 PF04004.8 CAM72192.1 - 1.3e-19 70.5 0.4 6e-19 68.3 0.0 2.1 2 0 0 2 2 2 1 Leo1-like protein Alb1 PF09135.6 CAM72193.1 - 8e-05 23.2 2.2 8e-05 23.2 1.5 2.3 2 0 0 2 2 2 1 Alb1 Pkinase PF00069.20 CAM72194.1 - 2.7e-08 33.3 0.0 3.4e-05 23.1 0.0 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAM72194.1 - 5.1e-07 29.0 0.1 3.9e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Sybindin PF04099.7 CAM72195.1 - 7.7e-17 61.3 0.0 8.8e-17 61.1 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family CHU_C PF13585.1 CAM72195.1 - 0.045 13.6 0.1 0.08 12.8 0.1 1.5 1 0 0 1 1 1 0 C-terminal domain of CHU protein family SpoU_methylase PF00588.14 CAM72196.1 - 3.3e-08 33.5 0.0 8.8e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 SpoU rRNA Methylase family Tctex-1 PF03645.8 CAM72198.1 - 6.9e-29 99.6 0.1 8e-29 99.4 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family DSPc PF00782.15 CAM72198.1 - 0.042 13.4 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain ATG16 PF08614.6 CAM72199.2 - 0.13 12.0 11.8 0.029 14.2 4.0 2.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF4200 PF13863.1 CAM72199.2 - 3.3 7.6 13.3 0.19 11.6 4.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Cupin_8 PF13621.1 CAM72201.1 - 1.6e-46 158.8 0.1 1.1e-45 156.1 0.0 2.2 3 0 0 3 3 3 1 Cupin-like domain LCM PF04072.9 CAM72201.1 - 3.9e-17 62.4 0.0 2.3e-08 33.8 0.0 2.8 2 1 0 2 2 2 2 Leucine carboxyl methyltransferase Kelch_5 PF13854.1 CAM72201.1 - 4.1e-10 39.3 1.6 0.4 10.6 0.0 5.7 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.1 CAM72201.1 - 4.4e-08 33.0 11.3 0.0053 16.8 0.1 5.5 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.1 CAM72201.1 - 1.6e-05 24.5 13.7 0.014 15.1 0.0 6.4 7 1 0 7 7 7 1 Galactose oxidase, central domain Kelch_6 PF13964.1 CAM72201.1 - 5.1e-05 23.2 0.5 20 5.5 0.0 6.0 6 0 0 6 6 6 0 Kelch motif Cupin_4 PF08007.7 CAM72201.1 - 0.00017 20.9 0.0 0.00069 18.9 0.0 1.9 1 1 0 1 1 1 1 Cupin superfamily protein U3_snoRNA_assoc PF08297.6 CAM72201.1 - 0.13 12.5 0.8 0.26 11.5 0.5 1.5 1 0 0 1 1 1 0 U3 snoRNA associated PPR_2 PF13041.1 CAM72202.1 - 2.3e-24 85.0 9.4 7.8e-07 28.9 0.0 9.2 6 3 3 9 9 9 6 PPR repeat family PPR PF01535.15 CAM72202.1 - 1.4e-22 77.9 25.5 0.012 15.5 0.0 12.0 13 0 0 13 13 13 6 PPR repeat PPR_3 PF13812.1 CAM72202.1 - 1.1e-17 62.6 23.0 0.0018 18.4 0.0 13.0 15 0 0 15 15 15 5 Pentatricopeptide repeat domain PPR_1 PF12854.2 CAM72202.1 - 7.6e-12 44.5 0.0 0.13 11.7 0.0 6.2 5 0 0 5 5 5 3 PPR repeat TPR_19 PF14559.1 CAM72202.1 - 0.0004 20.6 0.9 0.27 11.5 0.0 4.8 5 1 1 6 6 6 1 Tetratricopeptide repeat RNA_pol_Rpb4 PF03874.11 CAM72202.1 - 0.062 13.3 0.5 17 5.4 0.0 4.3 4 1 0 4 4 4 0 RNA polymerase Rpb4 DENN PF02141.16 CAM72203.1 - 7.3e-25 87.7 0.2 1.2e-24 87.0 0.2 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 CAM72203.1 - 0.042 13.8 0.0 0.088 12.7 0.0 1.6 1 0 0 1 1 1 0 uDENN domain TPR_14 PF13428.1 CAM72204.1 - 0.00078 19.8 3.8 0.4 11.4 0.1 3.9 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 CAM72204.1 - 0.0026 17.3 1.1 0.029 14.0 0.4 2.3 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.1 CAM72204.1 - 0.0092 16.6 3.5 0.026 15.1 2.5 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 CAM72204.1 - 0.0094 15.8 2.3 6.3 6.9 0.3 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CAM72204.1 - 0.019 15.2 0.7 0.052 13.8 0.5 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat YceG PF02618.11 CAM72204.1 - 0.031 13.3 0.1 1.8 7.5 0.0 2.1 2 0 0 2 2 2 0 YceG-like family TPR_4 PF07721.9 CAM72204.1 - 0.054 13.9 0.3 0.22 12.0 0.2 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Apc3 PF12895.2 CAM72204.1 - 0.095 12.8 0.3 0.19 11.8 0.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 CAM72204.1 - 0.25 11.0 1.2 35 4.2 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DnaJ PF00226.26 CAM72205.1 - 8.7e-23 79.8 0.9 8.7e-23 79.8 0.6 1.8 2 0 0 2 2 2 1 DnaJ domain CTDII PF01556.13 CAM72205.1 - 1.6e-19 69.5 0.4 1.5e-16 60.0 0.1 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CAM72205.1 - 3.2e-15 55.9 19.7 6.7e-15 54.8 13.6 1.6 1 0 0 1 1 1 1 DnaJ central domain Cytochrom_c3_2 PF14537.1 CAM72205.1 - 0.22 11.9 10.5 0.47 10.8 7.3 1.6 1 0 0 1 1 1 0 Cytochrome c3 HypA PF01155.14 CAM72205.1 - 0.29 10.8 8.2 0.35 10.5 0.8 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family PNPase PF03726.9 CAM72205.1 - 0.36 11.1 1.5 5.2 7.4 0.1 2.3 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain Integrin_B_tail PF07965.7 CAM72205.1 - 1.5 9.3 7.8 2.1 8.8 0.8 2.3 2 0 0 2 2 2 0 Integrin beta tail domain PADR1 PF08063.7 CAM72205.1 - 3.4 7.1 10.3 3.5 7.1 1.1 2.7 1 1 1 2 2 2 0 PADR1 (NUC008) domain DNA_pol_A_exo1 PF01612.15 CAM72206.1 - 1.6e-15 57.0 0.0 2.6e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease zf-CCHC PF00098.18 CAM72206.1 - 0.0028 17.4 2.7 0.0028 17.4 1.9 4.4 4 1 0 4 4 4 3 Zinc knuckle zf-C4_ClpX PF06689.8 CAM72206.1 - 0.23 11.0 7.5 2.9 7.4 1.1 2.7 2 0 0 2 2 2 0 ClpX C4-type zinc finger zf-CCHC_4 PF14392.1 CAM72206.1 - 2.5 7.8 29.2 0.14 11.7 0.8 3.8 4 0 0 4 4 4 0 Zinc knuckle Glyoxalase_2 PF12681.2 CAM72208.1 - 1.3e-14 54.6 0.0 1.6e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 CAM72208.1 - 1.6e-14 53.9 0.2 2.1e-14 53.5 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 CAM72208.1 - 3.9e-10 39.7 0.0 6.4e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.1 CAM72208.1 - 0.0042 16.7 0.0 0.0058 16.2 0.0 1.3 1 1 0 1 1 1 1 CppA N-terminal Glyoxalase_3 PF13468.1 CAM72208.1 - 0.089 12.6 0.0 7.5 6.4 0.0 2.4 2 1 0 2 2 2 0 Glyoxalase-like domain PAF-AH_p_II PF03403.8 CAM72209.1 - 7.5e-31 106.7 0.0 2e-30 105.3 0.0 1.6 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 CAM72209.1 - 4.9e-11 42.5 0.0 7.8e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CAM72209.1 - 8.2e-09 35.6 0.6 1.5e-08 34.7 0.4 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 CAM72209.1 - 0.00091 18.1 0.0 0.0041 16.0 0.0 1.9 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.15 CAM72209.1 - 0.015 14.8 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 CAM72209.1 - 0.075 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) ICMT PF04140.9 CAM72210.1 - 1.3e-19 70.1 2.2 1.3e-19 70.1 1.6 2.1 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CAM72210.1 - 1.1e-07 31.9 2.1 1.1e-07 31.9 1.4 2.9 3 1 1 4 4 4 1 Phospholipid methyltransferase DUF1295 PF06966.7 CAM72210.1 - 0.00045 19.5 2.3 0.00045 19.5 1.6 2.2 2 1 1 3 3 3 1 Protein of unknown function (DUF1295) RseC_MucC PF04246.7 CAM72210.1 - 1.4 8.4 4.5 0.28 10.7 0.3 1.8 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC PrgI PF12666.2 CAM72210.1 - 5.2 7.2 6.2 0.61 10.2 0.7 2.1 2 0 0 2 2 2 0 PrgI family protein NDUFA12 PF05071.11 CAM72211.1 - 2.7e-05 24.5 0.9 7.6e-05 23.1 0.7 1.7 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 zf-CCHC_2 PF13696.1 CAM72212.1 - 3.6e-05 23.1 4.9 8.6e-05 21.9 3.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-RING_2 PF13639.1 CAM72212.1 - 0.08 12.7 2.3 0.21 11.4 1.6 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.1 CAM72212.1 - 0.44 10.1 8.0 0.04 13.5 2.0 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain TF_Zn_Ribbon PF08271.7 CAM72212.1 - 0.98 8.7 6.4 0.42 9.9 0.9 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding zf-CCHC PF00098.18 CAM72212.1 - 1.1 9.3 9.6 0.084 12.8 3.1 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-RING_5 PF14634.1 CAM72212.1 - 1.2 8.8 9.2 0.98 9.2 2.2 2.4 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CAM72212.1 - 1.3 8.7 8.6 0.14 11.8 2.1 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 CAM72212.1 - 2.9 7.8 7.0 0.46 10.4 1.3 2.2 2 1 0 2 2 2 0 FYVE zinc finger ThiF PF00899.16 CAM72213.1 - 2.6e-47 160.0 0.2 2.1e-34 118.2 0.1 2.4 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 CAM72213.1 - 1.7e-28 97.9 0.4 1.7e-26 91.5 0.1 2.7 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CAM72213.1 - 3.9e-16 58.1 0.0 7.3e-16 57.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site 3HCDH_N PF02737.13 CAM72213.1 - 0.024 14.2 0.1 0.074 12.7 0.0 1.9 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rhamno_transf PF11316.3 CAM72213.1 - 0.097 11.8 0.2 0.19 10.9 0.1 1.4 1 0 0 1 1 1 0 Putative rhamnosyl transferase CrtC PF07143.6 CAM72214.1 - 1.1e-05 24.9 0.1 0.00011 21.6 0.0 2.3 2 0 0 2 2 2 1 Hydroxyneurosporene synthase (CrtC) FGGY_N PF00370.16 CAM72218.1 - 1.7e-66 224.0 0.0 2.3e-66 223.6 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 CAM72218.1 - 1.5e-60 204.2 1.2 3.1e-60 203.2 0.9 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DnaJ PF00226.26 CAM72219.1 - 3.9e-11 42.5 0.0 8.1e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain DEAD PF00270.24 CAM72220.1 - 3.3e-39 134.0 0.0 3.7e-37 127.4 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM72220.1 - 1.8e-26 91.8 0.2 3.7e-26 90.7 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 CAM72220.1 - 0.006 16.5 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.10 CAM72220.1 - 0.056 13.2 0.0 0.37 10.6 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CcmD PF04995.9 CAM72221.1 - 0.88 9.3 6.0 0.7 9.6 2.9 1.8 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) WD40 PF00400.27 CAM72222.1 - 0.34 10.8 6.8 2 8.4 0.1 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat Dynein_light PF01221.13 CAM72223.1 - 1.6e-12 47.2 0.1 3.3e-12 46.2 0.1 1.5 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.13 CAM72223.1 - 0.013 15.7 0.0 0.026 14.8 0.0 1.6 1 1 0 1 1 1 0 Ground-like domain IPK PF03770.11 CAM72224.1 - 3.7e-20 72.4 0.0 3e-19 69.4 0.0 2.1 1 1 0 1 1 1 1 Inositol polyphosphate kinase Flavokinase PF01687.12 CAM72226.1 - 1.3e-27 96.1 0.0 1.6e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase DUF1694 PF07997.6 CAM72226.1 - 0.0062 16.4 0.0 0.0092 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1694) DMA PF03474.9 CAM72226.1 - 0.089 12.6 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 DMRTA motif Pkinase PF00069.20 CAM72227.1 - 6.6e-41 140.1 0.0 1.4e-40 139.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM72227.1 - 8.1e-18 64.4 0.0 2e-16 59.8 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CAM72227.1 - 3e-05 23.8 2.5 0.00016 21.5 0.1 3.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.17 CAM72227.1 - 0.0091 15.3 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 CAM72227.1 - 0.021 13.8 0.0 0.062 12.3 0.0 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RPN7 PF10602.4 CAM72227.1 - 0.26 10.6 0.0 0.51 9.6 0.0 1.4 1 0 0 1 1 1 0 26S proteasome subunit RPN7 His_Phos_1 PF00300.17 CAM72229.1 - 5.7e-09 36.2 0.0 2.6e-08 34.1 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RRM_1 PF00076.17 CAM72230.1 - 8.5e-08 31.7 0.0 5.4e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM72230.1 - 3.3e-05 23.7 0.0 0.00015 21.6 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM72230.1 - 0.00015 21.5 0.0 0.00027 20.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_7 PF13499.1 CAM72231.1 - 8.5e-10 38.6 0.4 1.1e-08 35.0 0.2 2.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CAM72231.1 - 0.0019 17.3 5.6 0.044 13.1 0.1 3.6 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 CAM72231.1 - 0.0079 16.0 2.1 0.081 12.8 0.1 3.3 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 CAM72231.1 - 0.042 13.2 0.9 0.12 11.7 0.0 2.2 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.1 CAM72231.1 - 0.062 12.9 5.2 2.3 7.8 0.1 3.1 3 0 0 3 3 3 0 EF-hand domain pair Cys_Met_Meta_PP PF01053.15 CAM72233.1 - 4e-129 430.2 0.1 4.6e-129 430.0 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 CAM72233.1 - 8.4e-09 34.9 1.9 1.1e-08 34.5 0.3 1.7 1 1 1 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 CAM72233.1 - 0.00018 20.7 1.0 0.00042 19.5 0.7 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 CAM72233.1 - 0.00021 20.1 0.1 0.00041 19.1 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V SLA_LP_auto_ag PF05889.8 CAM72233.1 - 0.021 13.3 0.0 0.03 12.8 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) UPF0126 PF03458.8 CAM72234.1 - 0.07 12.7 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 UPF0126 domain AAA PF00004.24 CAM72235.1 - 1.6e-15 57.4 0.0 3.3e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CAM72235.1 - 1.3e-12 47.2 0.0 2e-10 39.9 0.0 2.2 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein DNA_pol3_delta2 PF13177.1 CAM72235.1 - 2.5e-11 43.4 0.0 4.3e-08 32.9 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 CAM72235.1 - 3.8e-08 33.2 0.0 1.4e-07 31.3 0.0 2.0 3 0 0 3 3 1 1 Replication factor C C-terminal domain AAA_22 PF13401.1 CAM72235.1 - 6.1e-07 29.6 0.1 3.7e-06 27.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CAM72235.1 - 7e-07 28.9 0.0 1.7e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 CAM72235.1 - 7e-07 29.3 0.1 5e-05 23.3 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.16 CAM72235.1 - 1.6e-06 27.4 0.0 2.7e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 CAM72235.1 - 2.2e-06 27.5 0.0 4.3e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CAM72235.1 - 2.3e-06 27.3 0.0 5e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CAM72235.1 - 1.6e-05 24.6 0.0 4.8e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 CAM72235.1 - 5.7e-05 22.8 0.0 0.0023 17.5 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_23 PF13476.1 CAM72235.1 - 0.00029 21.2 0.0 0.0004 20.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CAM72235.1 - 0.00031 19.8 0.0 0.00055 19.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 CAM72235.1 - 0.00055 19.4 0.0 0.0012 18.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Arch_ATPase PF01637.13 CAM72235.1 - 0.0012 18.5 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_33 PF13671.1 CAM72235.1 - 0.0013 18.6 0.0 0.0034 17.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 CAM72235.1 - 0.002 17.0 0.0 0.4 9.4 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_3 PF07726.6 CAM72235.1 - 0.0025 17.4 0.0 0.018 14.6 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 CAM72235.1 - 0.0039 16.6 0.1 0.7 9.2 0.0 2.2 1 1 1 2 2 2 1 AAA-like domain DUF2075 PF09848.4 CAM72235.1 - 0.0049 15.8 0.0 0.0073 15.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.1 CAM72235.1 - 0.0054 16.7 0.0 0.2 11.7 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain DUF815 PF05673.8 CAM72235.1 - 0.0059 15.5 0.0 0.0097 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 CAM72235.1 - 0.01 16.6 0.0 0.028 15.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 CAM72235.1 - 0.016 14.6 0.0 0.07 12.6 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.1 CAM72235.1 - 0.016 14.8 1.2 0.029 13.9 0.8 1.5 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 CAM72235.1 - 0.022 14.2 0.0 0.063 12.7 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family DSBA PF01323.15 CAM72235.1 - 0.026 14.0 0.1 0.062 12.8 0.0 1.6 2 0 0 2 2 1 0 DSBA-like thioredoxin domain AAA_25 PF13481.1 CAM72235.1 - 0.027 13.8 0.0 0.087 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 CAM72235.1 - 0.031 13.7 0.4 0.37 10.2 0.0 2.1 1 1 0 2 2 2 0 DEAD/DEAH box helicase IstB_IS21 PF01695.12 CAM72235.1 - 0.031 13.6 0.0 0.87 8.9 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein ArgK PF03308.11 CAM72235.1 - 0.072 11.8 0.1 0.42 9.3 0.0 2.0 1 1 0 1 1 1 0 ArgK protein AAA_2 PF07724.9 CAM72235.1 - 0.099 12.5 0.0 0.54 10.1 0.0 2.1 2 1 1 3 3 2 0 AAA domain (Cdc48 subfamily) AAA_28 PF13521.1 CAM72235.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CAM72235.1 - 0.15 12.4 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Pex19 PF04614.7 CAM72236.1 - 2.6e-15 56.7 26.4 5.4e-14 52.4 0.1 3.2 2 1 1 3 3 3 2 Pex19 protein family PPR_2 PF13041.1 CAM72236.1 - 0.17 11.8 0.3 0.54 10.2 0.2 1.9 1 0 0 1 1 1 0 PPR repeat family PP2C_C PF07830.8 CAM72236.1 - 1.5 8.9 3.6 8 6.6 0.1 3.1 3 0 0 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain GET2 PF08690.5 CAM72236.1 - 8 5.6 7.6 2.1 7.5 1.8 2.0 1 1 1 2 2 2 0 GET complex subunit GET2 HEM4 PF02602.10 CAM72237.1 - 0.031 13.5 1.6 0.037 13.2 1.0 1.3 1 1 0 1 1 1 0 Uroporphyrinogen-III synthase HemD DUF3446 PF11928.3 CAM72237.1 - 3.5 7.9 9.7 4.6 7.5 5.6 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3446) Ribosomal_L31e PF01198.14 CAM72239.1 - 4.4e-28 96.7 0.4 4.4e-28 96.7 0.3 1.6 2 0 0 2 2 2 1 Ribosomal protein L31e WD40 PF00400.27 CAM72240.1 - 2.6e-07 30.2 11.8 0.034 14.0 0.8 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat LRR_4 PF12799.2 CAM72241.1 - 1.2e-11 43.9 3.7 3.8e-06 26.3 0.2 3.1 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 CAM72241.1 - 7.5e-07 28.8 0.9 3.3e-06 26.7 0.3 1.8 1 1 1 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.1 CAM72241.1 - 9.1e-07 28.5 6.5 0.00032 20.3 1.3 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_6 PF13516.1 CAM72241.1 - 0.001 18.9 0.9 7.8 6.9 0.0 4.4 2 1 2 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.28 CAM72241.1 - 0.0066 16.3 2.7 4.6 7.6 0.0 4.1 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_7 PF13504.1 CAM72241.1 - 0.25 11.6 1.3 24 5.7 0.0 3.9 3 1 0 3 3 3 0 Leucine rich repeat TRAPP PF04051.11 CAM72242.1 - 1.9e-27 95.6 0.0 2.2e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Mito_carr PF00153.22 CAM72243.1 - 1.2e-53 178.8 0.2 4.7e-20 71.1 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein 6PGD PF00393.14 CAM72244.1 - 1.1e-87 293.9 0.0 1.5e-87 293.5 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 CAM72244.1 - 4.9e-48 163.0 0.1 7.5e-48 162.4 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 CAM72244.1 - 5.7e-06 26.4 0.1 0.00027 21.0 0.1 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 CAM72244.1 - 2.3e-05 24.1 0.1 3.8e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 CAM72244.1 - 5.9e-05 23.4 0.4 0.00012 22.4 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 CAM72244.1 - 0.00018 21.2 0.1 0.00032 20.4 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 CAM72244.1 - 0.002 17.3 0.4 0.0059 15.7 0.3 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 CAM72244.1 - 0.0024 17.3 0.1 0.004 16.6 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DAO PF01266.19 CAM72244.1 - 0.0038 16.1 0.0 0.005 15.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CAM72244.1 - 0.034 14.0 0.0 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.7 CAM72244.1 - 0.065 12.6 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain UDPG_MGDP_dh_N PF03721.9 CAM72244.1 - 0.079 12.3 0.1 0.19 11.1 0.1 1.7 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PGK PF00162.14 CAM72244.1 - 0.086 11.3 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Phosphoglycerate kinase TP_methylase PF00590.15 CAM72245.1 - 1.2e-21 77.3 1.9 2.4e-20 73.1 0.0 2.8 2 2 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases CAF-1_p150 PF11600.3 CAM72245.1 - 0.22 10.8 7.3 0.36 10.1 5.1 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2428 PF10350.4 CAM72246.1 - 1.1e-56 191.6 0.0 2.8e-56 190.3 0.0 1.7 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) CLASP_N PF12348.3 CAM72246.1 - 0.024 13.9 0.1 1.2 8.4 0.0 3.2 3 0 0 3 3 3 0 CLASP N terminal HEAT PF02985.17 CAM72246.1 - 0.36 11.0 14.9 17 5.8 0.2 7.1 7 0 0 7 7 7 0 HEAT repeat PARP_regulatory PF01358.13 CAM72248.1 - 1.5e-17 63.1 0.0 1.4e-10 40.3 0.0 2.5 2 1 0 2 2 2 2 Poly A polymerase regulatory subunit CDC50 PF03381.10 CAM72250.1 - 3.8e-87 291.9 0.0 5.8e-87 291.3 0.0 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Rep_fac-A_3 PF08661.6 CAM72254.1 - 5.9e-08 32.5 0.0 1.3e-07 31.4 0.0 1.5 1 1 0 1 1 1 1 Replication factor A protein 3 BHD_3 PF10405.4 CAM72255.1 - 3.2e-22 78.0 0.0 9.4e-22 76.5 0.0 1.8 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.10 CAM72255.1 - 5e-20 71.3 0.1 1.2e-19 70.1 0.1 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_1 PF10403.4 CAM72255.1 - 1.7e-12 46.6 0.0 3.4e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 CAM72255.1 - 8.4e-10 38.8 0.3 3.5e-09 36.8 0.0 2.3 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Geminin PF07412.7 CAM72255.1 - 0.027 14.1 0.1 0.059 13.0 0.1 1.5 1 0 0 1 1 1 0 Geminin peroxidase PF00141.18 CAM72256.1 - 2.7e-08 33.5 0.0 3.6e-08 33.1 0.0 1.3 1 1 0 1 1 1 1 Peroxidase Acyl_transf_1 PF00698.16 CAM72257.2 - 4e-20 72.3 0.0 5.8e-19 68.5 0.0 2.5 2 1 0 2 2 2 1 Acyl transferase domain Sprouty PF05210.8 CAM72257.2 - 0.044 13.7 0.6 0.1 12.6 0.4 1.6 1 0 0 1 1 1 0 Sprouty protein (Spry) RdRP PF05183.7 CAM72257.2 - 0.074 11.7 0.0 0.15 10.7 0.0 1.4 1 0 0 1 1 1 0 RNA dependent RNA polymerase SMC_N PF02463.14 CAM72261.1 - 1.3e-57 194.5 0.0 8.8e-57 191.8 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CAM72261.1 - 2.7e-26 91.8 0.0 1.6e-25 89.4 0.0 2.4 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CAM72261.1 - 3.6e-14 53.4 0.0 2e-06 28.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 CAM72261.1 - 3.5e-07 30.7 54.2 1.5e-05 25.4 20.0 5.0 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CAM72261.1 - 1.2e-06 27.8 0.0 2.9e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain OmpH PF03938.9 CAM72261.1 - 0.00059 19.8 2.7 0.00059 19.8 1.8 7.0 3 2 1 4 4 4 1 Outer membrane protein (OmpH-like) AAA_15 PF13175.1 CAM72261.1 - 0.0043 16.1 0.0 0.088 11.8 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain DUF4200 PF13863.1 CAM72261.1 - 0.0065 16.4 19.3 0.0065 16.4 13.4 7.5 4 3 4 9 9 9 2 Domain of unknown function (DUF4200) Reo_sigmaC PF04582.7 CAM72261.1 - 0.064 12.4 21.6 0.22 10.6 1.5 4.4 4 0 0 4 4 4 0 Reovirus sigma C capsid protein ABC_tran PF00005.22 CAM72261.1 - 0.16 12.3 0.0 0.16 12.3 0.0 5.9 4 2 0 4 4 4 0 ABC transporter FUSC_2 PF13515.1 CAM72262.1 - 3.8e-08 33.3 4.7 9.1e-08 32.0 3.2 1.6 1 0 0 1 1 1 1 Fusaric acid resistance protein-like FUSC PF04632.7 CAM72262.1 - 0.00039 19.0 3.7 0.0011 17.5 2.6 1.7 1 0 0 1 1 1 1 Fusaric acid resistance protein family DUF939 PF06081.6 CAM72262.1 - 0.0045 16.8 5.1 0.0045 16.8 3.5 2.0 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF939) CRAL_TRIO PF00650.15 CAM72263.1 - 9.6e-26 90.1 0.1 1.5e-25 89.5 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CAM72263.1 - 1.1e-08 35.0 1.1 1.1e-08 35.0 0.8 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain DUF2497 PF10691.4 CAM72264.1 - 0.0048 16.8 0.1 0.0048 16.8 0.1 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2497) DUF3584 PF12128.3 CAM72264.1 - 0.09 10.0 19.2 0.14 9.4 13.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.7 CAM72264.1 - 0.097 12.4 3.8 0.64 9.8 0.2 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.13 CAM72264.1 - 0.1 12.0 32.3 0.021 14.3 18.9 2.2 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain AAA_13 PF13166.1 CAM72264.1 - 0.24 9.7 4.4 0.43 8.9 3.1 1.4 1 0 0 1 1 1 0 AAA domain TBPIP PF07106.8 CAM72264.1 - 0.78 9.2 10.0 6.9 6.1 3.0 2.7 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Bap31 PF05529.7 CAM72264.1 - 1 8.7 4.3 0.63 9.4 1.4 1.8 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like Fib_alpha PF08702.5 CAM72264.1 - 1 9.4 10.2 23 5.0 1.6 3.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Tho2 PF11262.3 CAM72264.1 - 1.6 7.7 5.6 2.8 6.9 3.9 1.4 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 KH_1 PF00013.24 CAM72265.1 - 4.3e-07 29.4 1.3 1.3e-06 27.9 0.9 1.8 1 0 0 1 1 1 1 KH domain B12-binding_2 PF02607.12 CAM72266.1 - 0.012 15.5 0.0 2.7 8.0 0.0 2.8 3 0 0 3 3 3 0 B12 binding domain NIF PF03031.13 CAM72267.1 - 4.6e-29 101.1 0.1 1.1e-28 99.8 0.1 1.6 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase XPG_I_2 PF12813.2 CAM72269.1 - 7.6e-36 123.8 0.0 1.2e-35 123.1 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.13 CAM72269.1 - 1.9e-21 75.8 0.3 3.7e-21 74.9 0.2 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CAM72269.1 - 6.7e-20 71.2 0.0 1.7e-19 69.9 0.0 1.7 2 0 0 2 2 2 1 XPG N-terminal domain Methyltransf_23 PF13489.1 CAM72270.1 - 4e-26 91.6 0.0 6.6e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF2252 PF10009.4 CAM72270.1 - 8e-05 21.7 0.1 0.00012 21.1 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2252) Methyltransf_12 PF08242.7 CAM72270.1 - 0.0052 17.2 0.0 0.069 13.6 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Pro_isomerase PF00160.16 CAM72271.1 - 2.9e-28 99.0 0.0 4.4e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NifU_N PF01592.11 CAM72272.1 - 2e-48 163.4 0.0 2.5e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain MatE PF01554.13 CAM72273.1 - 1.9e-33 115.3 31.2 1.4e-18 67.0 9.0 3.4 3 0 0 3 3 3 3 MatE TfuA PF07812.7 CAM72273.1 - 0.027 13.9 0.0 0.068 12.6 0.0 1.6 1 0 0 1 1 1 0 TfuA-like protein NDUF_B7 PF05676.8 CAM72277.1 - 1.6e-08 33.8 0.3 2.6e-08 33.1 0.2 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Ribul_P_3_epim PF00834.14 CAM72278.1 - 5.4e-51 172.5 0.0 6.4e-51 172.3 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family PEX11 PF05648.9 CAM72279.1 - 7.7e-07 28.6 0.0 8.9e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF2985 PF11204.3 CAM72279.1 - 0.037 13.7 0.0 0.78 9.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2985) PEX11 PF05648.9 CAM72280.1 - 1.1e-14 54.3 0.0 2.9e-14 52.8 0.0 1.6 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF4190 PF13828.1 CAM72281.1 - 0.088 12.3 3.1 0.17 11.4 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) DUF2026 PF09641.5 CAM72282.1 - 0.0098 15.2 0.2 3.2 7.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2026) PhyH PF05721.8 CAM72284.1 - 0.09 12.7 0.0 0.56 10.2 0.0 2.1 2 1 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Cullin PF00888.17 CAM72285.1 - 3.4e-20 72.1 0.0 5.7e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Cullin family Ank PF00023.25 CAM72285.1 - 0.023 14.5 0.0 0.2 11.5 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat Antibiotic_NAT PF02522.9 CAM72285.1 - 0.026 13.7 0.0 0.046 12.9 0.0 1.4 1 0 0 1 1 1 0 Aminoglycoside 3-N-acetyltransferase Ank_3 PF13606.1 CAM72285.1 - 0.037 14.2 0.1 0.32 11.3 0.0 2.6 3 0 0 3 3 3 0 Ankyrin repeat Ank_4 PF13637.1 CAM72285.1 - 0.054 14.0 0.0 1.4 9.4 0.0 3.0 1 1 0 1 1 1 0 Ankyrin repeats (many copies) U3snoRNP10 PF12397.3 CAM72285.1 - 0.29 11.0 3.5 0.21 11.5 0.2 2.5 3 0 0 3 3 3 0 U3 small nucleolar RNA-associated protein 10 Ribosomal_L18e PF00828.14 CAM72286.1 - 1.2e-32 112.9 0.8 1.4e-32 112.7 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 CAAD PF14159.1 CAM72287.1 - 4.5 6.9 5.3 3.5 7.3 1.0 2.5 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Ribosomal_L18e PF00828.14 CAM72288.1 - 1.2e-32 112.9 0.8 1.4e-32 112.7 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Ribosomal_L14 PF00238.14 CAM72289.1 - 1e-36 125.3 0.0 1.2e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Cep57_CLD_2 PF14197.1 CAM72291.2 - 0.0062 16.4 2.9 0.0062 16.4 2.0 3.7 3 0 0 3 3 3 2 Centrosome localisation domain of PPC89 Cucumo_2B PF03263.8 CAM72291.2 - 0.091 13.0 4.8 0.17 12.1 0.2 2.8 2 1 1 3 3 3 0 Cucumovirus protein 2B AAA_27 PF13514.1 CAM72291.2 - 0.23 9.1 27.1 0.04 11.6 8.8 2.1 1 1 1 2 2 2 0 AAA domain CENP-F_leu_zip PF10473.4 CAM72291.2 - 0.33 10.8 14.6 0.87 9.4 1.6 3.3 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 CAM72291.2 - 0.98 8.9 21.8 1.4 8.5 12.1 2.7 3 0 0 3 3 3 0 IncA protein DUF4140 PF13600.1 CAM72291.2 - 1.1 9.7 14.5 12 6.3 2.6 3.7 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.10 CAM72291.2 - 1.5 8.3 15.0 2.2 7.7 0.1 4.5 3 2 1 4 4 4 0 Septum formation initiator TSC22 PF01166.13 CAM72291.2 - 3.2 7.7 8.4 3.2 7.7 0.9 3.6 3 1 0 3 3 3 0 TSC-22/dip/bun family Fib_alpha PF08702.5 CAM72291.2 - 4.8 7.2 8.2 17 5.5 1.2 2.9 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family SET PF00856.23 CAM72292.1 - 0.0029 17.9 0.0 0.042 14.1 0.0 2.2 1 1 0 1 1 1 1 SET domain Proteasome PF00227.21 CAM72293.1 - 7.2e-47 159.1 0.3 8.5e-47 158.9 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 CAM72293.1 - 0.00059 19.0 0.2 0.00059 19.0 0.1 1.9 2 0 0 2 2 2 1 Proteasome beta subunits C terminal DUF1375 PF07119.7 CAM72293.1 - 0.091 12.5 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1375) Ribosomal_S17 PF00366.15 CAM72294.1 - 3.2e-14 52.7 0.4 3.2e-14 52.7 0.3 1.7 2 0 0 2 2 2 1 Ribosomal protein S17 Cpn60_TCP1 PF00118.19 CAM72295.1 - 3.4e-149 497.5 1.9 4e-149 497.3 1.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NDK PF00334.14 CAM72296.1 - 1.1e-30 106.2 0.0 2.3e-27 95.4 0.0 2.5 1 1 1 2 2 2 2 Nucleoside diphosphate kinase V_ATPase_I PF01496.14 CAM72296.1 - 0.089 10.6 0.0 0.12 10.2 0.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ribosomal_S11 PF00411.14 CAM72296.1 - 0.12 12.5 1.0 6.4 6.9 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein S11 WD40 PF00400.27 CAM72297.1 - 1e-40 136.1 19.5 8.7e-11 41.2 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Sof1 PF04158.9 CAM72297.1 - 2.6e-08 33.7 4.6 5.3e-08 32.7 3.2 1.5 1 0 0 1 1 1 1 Sof1-like domain eIF2A PF08662.6 CAM72297.1 - 0.00094 18.9 0.0 0.0049 16.6 0.0 2.1 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CAM72297.1 - 0.028 12.5 2.9 2 6.4 0.6 3.2 2 2 0 2 2 2 0 Nucleoporin Nup120/160 EF-hand_7 PF13499.1 CAM72298.1 - 2.4e-11 43.5 0.2 2.3e-09 37.2 0.3 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CAM72298.1 - 1.9e-09 36.1 2.7 2.9e-08 32.4 0.0 3.6 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.1 CAM72298.1 - 6.1e-09 35.0 0.1 8.5e-06 25.2 0.0 3.2 3 1 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 CAM72298.1 - 2e-08 33.7 1.3 0.0021 17.6 0.1 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 CAM72298.1 - 4e-05 22.7 0.0 4e-05 22.7 0.0 2.6 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.1 CAM72298.1 - 0.0024 17.7 0.0 0.37 10.7 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain UPF0154 PF03672.8 CAM72298.1 - 0.0042 16.6 0.0 0.3 10.7 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) Baculo_p48 PF04878.8 CAM72298.1 - 0.12 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Baculovirus P48 protein SHIPPO-rpt PF07004.7 CAM72302.1 - 8.4e-15 54.8 45.2 0.12 13.2 1.8 9.9 10 0 0 10 10 10 9 Sperm-tail PG-rich repeat UNC-50 PF05216.8 CAM72303.1 - 2.7e-64 216.5 7.0 3.2e-64 216.2 4.8 1.0 1 0 0 1 1 1 1 UNC-50 family INCENP_N PF12178.3 CAM72304.1 - 1.2e-16 59.9 0.3 2.3e-16 59.0 0.2 1.5 1 0 0 1 1 1 1 Chromosome passenger complex (CPC) protein INCENP N terminal PROCN PF08083.6 CAM72305.1 - 3.6e-168 559.2 1.4 9.4e-168 557.9 1.0 1.8 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 CAM72305.1 - 7.6e-95 316.6 0.0 1.2e-94 315.9 0.0 1.3 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 CAM72305.1 - 1.5e-70 235.6 0.0 4.4e-70 234.1 0.0 1.9 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 CAM72305.1 - 1.1e-59 200.4 0.0 3.4e-59 198.8 0.0 2.0 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 CAM72305.1 - 3.4e-57 191.8 0.1 7.7e-57 190.6 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 CAM72305.1 - 1.9e-36 123.7 0.1 4.9e-36 122.4 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 CAM72305.1 - 3.1e-36 123.8 0.0 7.1e-36 122.6 0.0 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain Pkinase PF00069.20 CAM72306.1 - 1.7e-68 230.6 0.0 2e-68 230.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM72306.1 - 8.5e-32 110.2 0.0 1.1e-31 109.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM72306.1 - 0.00042 19.3 0.0 0.00052 19.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.19 CAM72306.1 - 0.13 12.7 0.3 0.26 11.8 0.2 1.5 1 0 0 1 1 1 0 Protein kinase C terminal domain zf-MIZ PF02891.15 CAM72307.1 - 3.2e-19 68.1 1.5 6.7e-19 67.1 1.0 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 CAM72307.1 - 0.0004 19.8 0.1 0.0009 18.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Mito_carr PF00153.22 CAM72309.1 - 2.5e-42 142.4 0.9 2.3e-21 75.2 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein HECT PF00632.20 CAM72310.1 - 4.9e-55 186.9 0.0 9.4e-55 185.9 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Pkinase PF00069.20 CAM72310.1 - 1.7e-50 171.6 0.0 3.2e-50 170.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM72310.1 - 3.2e-30 105.0 0.0 7.8e-30 103.7 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_11 PF13414.1 CAM72310.1 - 1.2e-18 66.5 3.7 2.9e-15 55.6 0.8 2.9 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 CAM72310.1 - 3.4e-13 48.5 2.3 4.8e-06 25.9 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CAM72310.1 - 6.2e-13 47.5 4.0 2.7e-05 23.7 0.1 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 CAM72310.1 - 1e-07 31.2 1.6 0.33 10.8 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat Kinase-like PF14531.1 CAM72310.1 - 1.6e-05 24.0 0.0 4.2e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Kinase-like TPR_14 PF13428.1 CAM72310.1 - 0.00013 22.2 4.3 0.18 12.5 0.0 4.1 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 CAM72310.1 - 0.00015 21.6 0.2 0.074 13.2 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 CAM72310.1 - 0.00028 20.4 0.4 0.02 14.6 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat APH PF01636.18 CAM72310.1 - 0.00044 20.0 0.0 0.00044 20.0 0.0 2.5 2 1 0 2 2 1 1 Phosphotransferase enzyme family TPR_16 PF13432.1 CAM72310.1 - 0.0014 19.2 8.0 0.016 15.8 0.0 3.4 3 0 0 3 3 2 1 Tetratricopeptide repeat RIO1 PF01163.17 CAM72310.1 - 0.0032 16.8 0.0 0.01 15.1 0.0 1.8 1 0 0 1 1 1 1 RIO1 family TPR_19 PF14559.1 CAM72310.1 - 0.0075 16.5 6.8 0.23 11.8 0.0 3.8 3 1 1 4 4 3 1 Tetratricopeptide repeat EMP24_GP25L PF01105.19 CAM72310.1 - 0.028 14.1 2.7 0.081 12.6 1.9 1.7 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD TPR_6 PF13174.1 CAM72310.1 - 0.035 14.5 0.2 2.4 8.8 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat tRNA-synt_2c PF01411.14 CAM72310.1 - 0.042 12.1 3.8 0.074 11.3 2.6 1.4 1 0 0 1 1 1 0 tRNA synthetases class II (A) TPR_9 PF13371.1 CAM72310.1 - 0.13 12.1 4.7 0.69 9.8 0.0 3.5 4 0 0 4 4 2 0 Tetratricopeptide repeat AAA_13 PF13166.1 CAM72310.1 - 4.6 5.5 21.0 0.54 8.6 8.1 2.2 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.20 CAM72311.1 - 1.5e-68 230.7 0.0 1.8e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM72311.1 - 6.6e-32 110.5 0.0 1e-31 110.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM72311.1 - 0.00039 19.4 0.0 0.00049 19.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.19 CAM72311.1 - 0.019 15.4 0.4 0.039 14.4 0.3 1.5 1 0 0 1 1 1 0 Protein kinase C terminal domain Abhydrolase_5 PF12695.2 CAM72312.1 - 1.1e-23 83.6 0.0 4.5e-23 81.6 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CAM72312.1 - 8.7e-17 61.7 0.1 3.8e-16 59.6 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CAM72312.1 - 2.3e-06 26.9 0.0 1.6e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 CAM72312.1 - 2.9e-06 27.0 0.0 0.0039 16.7 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 CAM72312.1 - 4e-06 26.4 0.0 0.012 15.1 0.0 2.3 1 1 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 CAM72312.1 - 4.8e-06 26.3 0.1 7.9e-06 25.5 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.7 CAM72312.1 - 0.0002 19.9 0.1 0.0067 14.9 0.0 2.5 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 CAM72312.1 - 0.00028 20.6 0.0 0.00063 19.5 0.0 1.5 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 CAM72312.1 - 0.00078 18.7 0.0 0.057 12.6 0.0 2.2 1 1 0 2 2 2 1 Dienelactone hydrolase family Hydrolase_4 PF12146.3 CAM72312.1 - 0.0017 18.1 0.1 0.0055 16.5 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S15 PF02129.13 CAM72312.1 - 0.0039 16.6 0.0 0.8 9.0 0.0 2.2 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DUF818 PF05677.7 CAM72312.1 - 0.0098 14.6 0.0 0.013 14.2 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) DUF1100 PF06500.6 CAM72312.1 - 0.029 12.9 0.0 0.036 12.6 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) UPF0227 PF05728.7 CAM72312.1 - 0.044 13.5 0.0 0.12 12.0 0.0 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) FSH1 PF03959.8 CAM72312.1 - 0.05 13.0 0.0 0.078 12.4 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) IncA PF04156.9 CAM72312.1 - 0.1 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 IncA protein PGAP1 PF07819.8 CAM72312.1 - 0.11 12.0 0.0 0.27 10.7 0.0 1.6 1 1 0 1 1 1 0 PGAP1-like protein BMF PF15185.1 CAM72312.1 - 0.29 10.4 0.6 0.49 9.6 0.4 1.3 1 0 0 1 1 1 0 Bcl-2-modifying factor, apoptosis DEAD PF00270.24 CAM72313.1 - 4.2e-35 120.7 0.0 2.4e-34 118.2 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM72313.1 - 2.8e-22 78.3 0.0 1.3e-21 76.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CAM72313.1 - 1.9e-16 59.3 0.0 4.6e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 CAM72313.1 - 5.8e-06 26.2 0.0 1.5e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Metal_resist PF13801.1 CAM72313.1 - 0.8 9.7 13.7 0.086 12.8 3.1 3.0 2 0 0 2 2 2 0 Heavy-metal resistance DnaJ PF00226.26 CAM72314.1 - 1.9e-16 59.5 0.0 1.8e-15 56.4 0.0 2.4 1 1 0 1 1 1 1 DnaJ domain FadA PF09403.5 CAM72314.1 - 3.9 7.5 7.7 4.5 7.3 4.6 1.6 1 1 0 1 1 1 0 Adhesion protein FadA MmgE_PrpD PF03972.9 CAM72315.1 - 0.04 12.0 0.1 0.041 12.0 0.1 1.1 1 0 0 1 1 1 0 MmgE/PrpD family Pkinase PF00069.20 CAM72316.1 - 1.7e-40 138.8 0.0 4.7e-40 137.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM72316.1 - 4.9e-22 78.2 0.0 2.5e-21 75.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM72316.1 - 1.4e-09 37.3 0.0 2.4e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 CAM72316.1 - 0.6 8.8 0.0 0.97 8.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 zf-RING_4 PF14570.1 CAM72316.1 - 4.2 7.0 17.5 7.3 6.2 12.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RIIa PF02197.12 CAM72317.1 - 1.8e-11 43.2 0.0 1.6e-10 40.2 0.0 2.4 2 0 0 2 2 2 1 Regulatory subunit of type II PKA R-subunit EF-hand_7 PF13499.1 CAM72317.1 - 7.1e-05 22.8 0.0 0.0012 18.9 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CAM72317.1 - 9.3e-05 22.0 0.0 0.39 10.7 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 CAM72317.1 - 0.0065 15.7 0.0 1.4 8.3 0.0 2.8 2 0 0 2 2 2 2 EF hand TPR_11 PF13414.1 CAM72318.1 - 4.2e-15 55.1 12.0 5.8e-06 25.8 0.1 4.6 4 1 0 4 4 4 4 TPR repeat TPR_2 PF07719.12 CAM72318.1 - 4.4e-14 51.1 14.6 0.0017 18.1 0.1 6.9 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 CAM72318.1 - 5e-13 49.1 10.9 9.4e-06 25.8 0.3 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 CAM72318.1 - 8.6e-12 45.3 17.0 5.3e-05 23.7 0.1 4.7 3 1 3 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 CAM72318.1 - 6.9e-09 35.5 20.0 0.00016 22.0 0.3 6.6 3 3 4 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 CAM72318.1 - 3.6e-07 30.0 18.9 0.057 13.3 0.1 5.7 2 2 3 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 CAM72318.1 - 9.5e-06 25.4 8.4 0.4 10.9 0.0 5.0 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 CAM72318.1 - 1.8e-05 24.1 12.5 1.6 8.4 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.9 CAM72318.1 - 2.5e-05 24.2 11.6 0.011 16.0 0.7 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 CAM72318.1 - 7.4e-05 22.9 11.3 0.098 13.1 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 CAM72318.1 - 0.00015 21.2 14.9 0.022 14.5 0.1 5.8 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.1 CAM72318.1 - 0.0002 20.5 5.3 0.051 12.6 0.2 3.1 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 CAM72318.1 - 0.0012 18.4 5.6 11 6.0 1.2 6.2 6 1 1 7 7 7 0 Tetratricopeptide repeat Apc3 PF12895.2 CAM72318.1 - 0.018 15.1 8.5 0.24 11.5 1.1 3.7 1 1 3 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 CAM72318.1 - 0.088 12.7 0.4 0.088 12.7 0.3 3.8 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain CbiX PF01903.12 CAM72318.1 - 0.1 12.7 0.1 0.39 10.8 0.0 2.0 2 0 0 2 2 2 0 CbiX Alkyl_sulf_dimr PF14863.1 CAM72318.1 - 0.16 12.1 3.9 0.19 11.9 0.4 2.6 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation TPR_21 PF09976.4 CAM72318.1 - 0.48 10.3 8.0 0.71 9.8 0.5 3.5 1 1 2 3 3 3 0 Tetratricopeptide repeat SF3b10 PF07189.6 CAM72320.1 - 7.1e-16 57.8 0.0 7.9e-16 57.6 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) SseB PF07179.7 CAM72321.1 - 0.0013 18.5 0.0 0.53 10.1 0.0 2.3 2 0 0 2 2 2 2 SseB protein N-terminal domain HD_3 PF13023.1 CAM72322.1 - 5.8e-37 126.9 0.0 7.2e-37 126.6 0.0 1.2 1 0 0 1 1 1 1 HD domain HD PF01966.17 CAM72322.1 - 2.1e-06 27.7 0.0 3.6e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 HD domain DUF1467 PF07330.7 CAM72323.2 - 0.018 14.8 0.4 0.056 13.2 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1467) RRM_1 PF00076.17 CAM72325.1 - 2.2e-73 241.8 0.0 7.7e-18 63.8 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM72325.1 - 2.1e-50 168.5 0.0 2.3e-12 46.7 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 CAM72325.1 - 2.3e-28 97.6 0.2 4.4e-28 96.7 0.1 1.5 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.1 CAM72325.1 - 3.6e-25 87.5 0.0 2.5e-07 30.4 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CAM72325.1 - 1.8e-08 34.1 3.9 0.42 10.4 0.2 4.4 3 1 1 4 4 4 4 RNA binding motif Nup35_RRM_2 PF14605.1 CAM72325.1 - 5.3e-06 26.1 0.0 0.24 11.2 0.0 4.1 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 CAM72325.1 - 0.021 14.5 3.0 0.65 9.7 0.0 3.6 2 1 1 3 3 3 0 Limkain b1 FliG_M PF14841.1 CAM72325.1 - 0.069 13.1 0.1 9.9 6.2 0.0 2.6 1 1 1 2 2 2 0 FliG middle domain TB2_DP1_HVA22 PF03134.14 CAM72326.1 - 0.41 10.4 2.8 0.29 10.9 0.5 1.8 2 0 0 2 2 2 0 TB2/DP1, HVA22 family GTP_EFTU PF00009.22 CAM72327.1 - 1.7e-41 141.7 0.0 4.1e-40 137.2 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CAM72327.1 - 1.1e-07 31.9 0.0 2.4e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 CAM72327.1 - 0.0031 17.4 0.0 0.0077 16.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 CAM72327.1 - 0.018 15.1 0.1 0.047 13.8 0.1 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 2 HBS1_N PF08938.5 CAM72327.1 - 0.044 13.9 4.6 0.22 11.6 0.0 2.4 2 0 0 2 2 2 0 HBS1 N-terminus FeoB_N PF02421.13 CAM72327.1 - 0.069 12.4 0.1 0.38 10.0 0.0 2.2 2 1 0 2 2 2 0 Ferrous iron transport protein B Herpes_capsid PF06112.6 CAM72327.1 - 4.1 7.4 10.8 0.84 9.6 2.3 2.5 3 0 0 3 3 3 0 Gammaherpesvirus capsid protein DUF2009 PF09418.5 CAM72328.1 - 4.5e-213 708.1 0.1 5.1e-213 707.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) RNA_pol_Rpc4 PF05132.9 CAM72329.1 - 2e-06 27.7 0.0 4.4e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase III RPC4 BBS1 PF14779.1 CAM72330.1 - 5.8e-59 199.1 0.0 1.8e-58 197.5 0.0 1.8 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 1 PHTB1_N PF14727.1 CAM72330.1 - 0.0036 16.3 0.0 0.042 12.7 0.0 2.3 2 1 1 3 3 3 1 PTHB1 N-terminus BBS2_Mid PF14783.1 CAM72330.1 - 0.0072 16.0 0.0 4.9 6.9 0.0 3.4 2 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region DUF3639 PF12341.3 CAM72330.1 - 0.45 10.5 2.2 27 4.8 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3639) VMA21 PF09446.5 CAM72331.1 - 0.059 13.3 5.6 0.093 12.6 3.9 1.3 1 0 0 1 1 1 0 VMA21-like domain Neurensin PF14927.1 CAM72331.1 - 0.083 12.2 0.7 0.46 9.8 0.0 2.0 1 1 1 2 2 2 0 Neurensin DUF3123 PF11321.3 CAM72331.1 - 5.9 7.2 7.2 15 5.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) Syja_N PF02383.13 CAM72335.1 - 1.5e-25 89.6 0.0 1.6e-23 83.0 0.0 2.2 2 0 0 2 2 2 2 SacI homology domain PPR_2 PF13041.1 CAM72336.1 - 0.017 15.0 0.0 0.056 13.4 0.0 1.8 2 0 0 2 2 2 0 PPR repeat family Methyltransf_23 PF13489.1 CAM72337.1 - 3.7e-24 85.2 0.0 5.6e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAM72337.1 - 2.2e-19 69.5 0.0 1.1e-18 67.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CAM72337.1 - 3.8e-18 65.7 0.0 6.3e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAM72337.1 - 3.4e-14 53.1 0.0 7e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAM72337.1 - 9.4e-13 48.7 0.0 1.4e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CAM72337.1 - 3.1e-10 40.1 0.0 5.2e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAM72337.1 - 9.2e-10 38.7 0.1 1.6e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CAM72337.1 - 6.1e-08 32.0 0.1 1.9e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 CAM72337.1 - 4.6e-07 29.2 0.0 6.7e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 CAM72337.1 - 5.2e-06 26.1 0.0 7.9e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.11 CAM72337.1 - 5.4e-06 25.5 0.0 9.2e-06 24.7 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme NodS PF05401.6 CAM72337.1 - 6.7e-06 25.6 0.3 4e-05 23.1 0.2 1.9 1 1 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.9 CAM72337.1 - 2.6e-05 23.6 0.1 5.1e-05 22.7 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 CAM72337.1 - 0.00092 18.7 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 CAM72337.1 - 0.0012 18.0 0.0 0.0022 17.1 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.7 CAM72337.1 - 0.0069 15.7 0.4 0.16 11.3 0.0 2.2 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW TPMT PF05724.6 CAM72337.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) TehB PF03848.9 CAM72337.1 - 0.015 14.4 0.0 0.047 12.8 0.0 1.8 1 1 0 1 1 1 0 Tellurite resistance protein TehB RrnaAD PF00398.15 CAM72337.1 - 0.033 13.1 0.0 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DREV PF05219.7 CAM72337.1 - 0.049 12.5 0.0 0.31 9.8 0.0 1.9 1 1 0 1 1 1 0 DREV methyltransferase FYVE PF01363.16 CAM72338.1 - 2.9e-16 59.1 8.0 2.9e-16 59.1 5.5 2.7 2 1 0 2 2 2 1 FYVE zinc finger DUF3584 PF12128.3 CAM72338.1 - 0.28 8.4 41.3 0.34 8.1 28.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF572 PF04502.8 CAM72338.1 - 1.2 8.3 30.8 1.7 7.7 21.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Borrelia_P83 PF05262.6 CAM72338.1 - 6.5 4.9 37.7 8.7 4.4 26.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein GAGA_bind PF06217.7 CAM72338.1 - 8.5 6.2 22.9 13 5.6 15.9 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Asp-B-Hydro_N PF05279.6 CAM72338.1 - 9.2 6.0 39.0 14 5.4 27.0 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region bZIP_1 PF00170.16 CAM72340.1 - 0.065 13.1 25.8 0.3 11.0 3.8 5.0 4 1 0 4 4 4 0 bZIP transcription factor Reo_sigmaC PF04582.7 CAM72340.1 - 1 8.4 13.5 0.17 11.0 4.0 2.7 2 1 1 3 3 3 0 Reovirus sigma C capsid protein GAS PF13851.1 CAM72340.1 - 2.2 7.4 51.5 0.062 12.5 7.5 4.2 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding DUF948 PF06103.6 CAM72340.1 - 3.6 7.5 15.9 0.13 12.1 1.5 3.3 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) PalH PF08733.5 CAM72343.1 - 0.087 11.6 0.2 0.1 11.4 0.1 1.0 1 0 0 1 1 1 0 PalH/RIM21 Claudin_2 PF13903.1 CAM72343.1 - 0.12 12.0 3.3 0.36 10.4 2.3 1.7 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction IncA PF04156.9 CAM72343.1 - 0.49 9.9 2.9 6.4 6.3 0.9 2.1 2 0 0 2 2 2 0 IncA protein Hydrolase_6 PF13344.1 CAM72344.1 - 3.9e-23 81.2 0.0 8e-23 80.2 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CAM72344.1 - 3.1e-13 49.2 0.0 8.8e-13 47.7 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 CAM72344.1 - 0.0035 17.5 0.5 1.3 9.1 0.0 3.1 3 1 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CAM72344.1 - 0.03 14.7 0.1 15 5.9 0.0 2.6 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF4121 PF13497.1 CAM72344.1 - 0.17 10.8 0.0 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) PIH1 PF08190.7 CAM72345.1 - 4.1e-120 401.1 0.0 4.1e-120 401.1 0.0 2.3 3 0 0 3 3 3 1 pre-RNA processing PIH1/Nop17 PGAP1 PF07819.8 CAM72347.1 - 8.3e-13 48.4 0.0 1.8e-05 24.4 0.0 2.3 2 0 0 2 2 2 2 PGAP1-like protein Abhydrolase_6 PF12697.2 CAM72347.1 - 1.6e-06 28.1 1.9 3.1e-05 23.9 0.3 2.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CAM72347.1 - 0.024 14.3 0.0 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAM72347.1 - 0.033 13.7 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1744 PF08490.7 CAM72348.1 - 3.5e-48 164.1 0.0 5.3e-47 160.2 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 CAM72348.1 - 1.5e-45 155.5 0.0 2.6e-45 154.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 CAM72348.1 - 1.4e-19 70.2 0.0 2.1e-16 59.7 0.0 2.9 2 1 0 2 2 2 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 CAM72348.1 - 1.1e-09 38.1 0.5 2e-08 34.0 0.4 2.5 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 CAM72348.1 - 2.3e-08 34.0 0.3 1.1e-07 31.8 0.1 2.3 2 1 0 2 2 2 1 RNase_H superfamily zf-DNA_Pol PF08996.5 CAM72348.1 - 0.00019 20.8 2.2 0.0005 19.4 1.6 1.6 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger zf-3CxxC PF13695.1 CAM72349.1 - 2.7e-09 37.1 3.0 3.2e-09 36.8 2.1 1.1 1 0 0 1 1 1 1 Zinc-binding domain zinc_ribbon_4 PF13717.1 CAM72349.1 - 0.0041 16.7 0.6 0.0041 16.7 0.4 2.2 2 0 0 2 2 2 1 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CAM72349.1 - 0.0042 16.6 0.5 0.0042 16.6 0.3 2.2 2 0 0 2 2 2 1 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 CAM72349.1 - 0.014 15.1 0.9 0.43 10.4 0.1 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-DNA_Pol PF08996.5 CAM72349.1 - 0.042 13.2 0.5 0.056 12.8 0.3 1.1 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger Elf1 PF05129.8 CAM72349.1 - 0.066 12.9 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-dskA_traR PF01258.12 CAM72349.1 - 0.48 10.2 3.2 2 8.2 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger C1_3 PF07649.7 CAM72349.1 - 0.78 9.8 2.7 17 5.5 0.3 2.2 2 0 0 2 2 2 0 C1-like domain HC2 PF07382.6 CAM72350.1 - 2.2e-12 47.2 51.1 1.4e-06 28.2 15.7 3.4 1 1 2 3 3 3 3 Histone H1-like nucleoprotein HC2 LisH PF08513.6 CAM72350.1 - 0.14 11.9 0.3 0.2 11.4 0.2 1.2 1 0 0 1 1 1 0 LisH TPR_12 PF13424.1 CAM72351.1 - 4.9e-05 23.1 10.3 0.047 13.6 0.6 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat Snf7 PF03357.16 CAM72352.1 - 2e-19 69.6 18.0 2e-19 69.6 12.5 1.7 1 1 1 2 2 2 1 Snf7 Mating_C PF12737.2 CAM72352.1 - 0.057 12.3 0.1 0.08 11.8 0.1 1.3 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 AA_permease_2 PF13520.1 CAM72353.1 - 4.3e-37 127.6 42.2 5.5e-37 127.3 29.2 1.0 1 0 0 1 1 1 1 Amino acid permease Mito_carr PF00153.22 CAM72354.1 - 5.3e-32 109.3 9.7 1.7e-17 62.8 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein ArsB PF02040.10 CAM72354.1 - 0.0025 16.8 0.4 0.0049 15.8 0.1 1.5 2 0 0 2 2 2 1 Arsenical pump membrane protein Mito_carr PF00153.22 CAM72355.1 - 2e-33 113.9 8.5 1.4e-18 66.3 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein ArsB PF02040.10 CAM72355.1 - 0.0026 16.7 0.5 0.0045 15.9 0.1 1.5 2 0 0 2 2 2 1 Arsenical pump membrane protein PLC-beta_C PF08703.5 CAM72356.1 - 0.08 12.6 1.1 0.12 12.0 0.7 1.2 1 0 0 1 1 1 0 PLC-beta C terminal zf-CCCH PF00642.19 CAM72357.1 - 0.23 11.2 2.6 0.38 10.4 1.8 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LSM PF01423.17 CAM72358.1 - 1e-18 66.6 0.1 1.1e-18 66.4 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CAM72358.1 - 4e-05 23.4 0.0 4.4e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.2 CAM72358.1 - 0.03 14.1 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain CS PF04969.11 CAM72359.1 - 1.7e-09 38.0 0.0 2.4e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 CS domain ARL2_Bind_BART PF11527.3 CAM72360.1 - 0.0027 17.4 0.3 0.0045 16.7 0.2 1.5 1 1 0 1 1 1 1 The ARF-like 2 binding protein BART EMG1 PF03587.9 CAM72360.1 - 0.072 12.3 0.0 0.088 12.0 0.0 1.2 1 0 0 1 1 1 0 EMG1/NEP1 methyltransferase Rhomboid_SP PF12595.3 CAM72360.1 - 0.85 9.1 3.9 0.58 9.7 0.2 1.9 2 0 0 2 2 2 0 Rhomboid serine protease zf-Apc11 PF12861.2 CAM72362.1 - 2.9e-29 100.7 10.3 3.2e-29 100.6 7.1 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CAM72362.1 - 1.9e-25 88.7 11.4 2.1e-25 88.5 7.9 1.0 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CAM72362.1 - 3.8e-07 29.8 22.5 1.8e-06 27.7 14.8 2.6 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 CAM72362.1 - 2.5e-05 23.8 14.7 2.8e-05 23.6 9.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CAM72362.1 - 0.00012 21.7 17.4 0.036 13.7 8.3 2.5 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAM72362.1 - 0.00042 20.2 16.4 0.005 16.8 10.6 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAM72362.1 - 0.00053 19.6 17.9 0.0042 16.7 11.5 2.3 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.1 CAM72362.1 - 0.0023 17.4 3.1 0.0023 17.4 2.2 2.9 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 CAM72362.1 - 0.012 15.4 4.5 0.012 15.4 3.1 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-HIT PF04438.11 CAM72362.1 - 0.12 12.0 11.0 0.27 10.9 4.2 2.4 2 1 0 2 2 2 0 HIT zinc finger zf-Nse PF11789.3 CAM72362.1 - 1.1 8.8 10.6 1.7 8.2 7.3 1.4 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.6 CAM72362.1 - 1.1 9.3 16.6 9.9 6.2 11.5 2.4 1 1 0 1 1 1 0 RING-like domain PHD PF00628.24 CAM72362.1 - 2.6 7.7 15.0 38 4.0 10.4 2.5 1 1 0 1 1 1 0 PHD-finger zf-HC5HC2H_2 PF13832.1 CAM72362.1 - 2.8 7.9 10.2 4.4 7.3 7.1 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CAM72362.1 - 3.7 7.7 12.1 20 5.4 8.4 2.0 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-UDP PF14569.1 CAM72362.1 - 6.3 6.6 8.3 13 5.5 0.7 2.2 1 1 1 2 2 2 0 Zinc-binding RING-finger DUF962 PF06127.6 CAM72364.1 - 1.5e-22 79.3 1.7 2.6e-22 78.5 1.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) FPL PF09758.4 CAM72366.2 - 3.8e-55 185.7 0.5 6.7e-55 184.9 0.4 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein SET PF00856.23 CAM72367.2 - 1.6e-22 80.5 12.6 0.0011 19.2 0.0 10.3 12 0 0 12 12 12 5 SET domain SAF PF08666.7 CAM72367.2 - 5e-06 26.8 0.0 40 4.7 0.0 8.8 11 1 0 11 11 11 1 SAF domain DUF1582 PF07621.6 CAM72367.2 - 2.6 8.1 11.2 21 5.3 0.1 5.3 5 0 0 5 5 5 0 Protein of unknown function (DUF1582) zf-HC5HC2H PF13771.1 CAM72368.1 - 3.6e-15 55.8 2.4 7.5e-15 54.8 1.6 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 CAM72368.1 - 1.3e-07 31.6 6.8 2.3e-07 30.7 4.7 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain SseC PF04888.7 CAM72369.1 - 0.0059 15.9 3.8 0.008 15.5 2.6 1.2 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family 60KD_IMP PF02096.15 CAM72370.1 - 2.2e-12 47.0 0.0 3.5e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein DUF3611 PF12263.3 CAM72370.1 - 0.034 13.5 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) PS_Dcarbxylase PF02666.10 CAM72371.1 - 8.9e-39 132.8 0.0 1.1e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Lebercilin PF15619.1 CAM72372.1 - 0.00098 18.6 7.0 0.00098 18.6 4.9 4.9 6 0 0 6 6 6 2 Ciliary protein causing Leber congenital amaurosis disease AAA_13 PF13166.1 CAM72372.1 - 0.021 13.3 6.0 0.059 11.8 4.2 1.7 1 1 0 1 1 1 0 AAA domain APG6 PF04111.7 CAM72372.1 - 2.3 7.1 26.1 0.13 11.3 1.6 3.7 3 1 0 3 3 3 0 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 CAM72372.1 - 7 6.4 31.3 0.81 9.4 6.1 4.5 4 1 0 4 4 4 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.14 CAM72372.1 - 9.3 3.9 11.6 0.97 7.2 2.8 2.4 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DnaJ PF00226.26 CAM72375.1 - 1.7e-15 56.5 0.2 3.7e-15 55.3 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain PSD1 PF07587.6 CAM72375.1 - 0.085 12.2 0.4 7 5.9 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1553) Atg14 PF10186.4 CAM72376.1 - 0.0017 17.3 17.5 0.002 17.1 12.1 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 EcoRII-C PF09019.6 CAM72376.1 - 0.0075 16.1 2.2 0.012 15.4 1.5 1.4 1 1 0 1 1 1 1 EcoRII C terminal AKNA PF12443.3 CAM72376.1 - 0.051 13.5 6.3 0.2 11.7 3.4 2.1 1 1 1 2 2 2 0 AT-hook-containing transcription factor Med29 PF11568.3 CAM72376.1 - 0.095 12.7 5.3 0.13 12.2 3.1 1.7 1 1 1 2 2 2 0 Mediator complex subunit 29 Baculo_LEF-11 PF06385.7 CAM72376.1 - 0.095 12.8 6.9 0.88 9.7 0.4 2.1 1 1 1 2 2 2 0 Baculovirus LEF-11 protein FAM178 PF14816.1 CAM72376.1 - 0.1 11.2 3.8 0.11 11.1 2.7 1.1 1 0 0 1 1 1 0 Family of unknown function, FAM178 MGS PF02142.17 CAM72376.1 - 0.18 11.7 1.9 0.29 11.0 1.3 1.3 1 1 0 1 1 1 0 MGS-like domain Cgr1 PF03879.9 CAM72376.1 - 0.36 11.0 22.7 0.43 10.7 15.8 1.2 1 0 0 1 1 1 0 Cgr1 family Vfa1 PF08432.5 CAM72376.1 - 0.67 9.9 13.2 0.8 9.6 9.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Casc1 PF12366.3 CAM72376.1 - 0.81 9.1 9.0 0.97 8.8 6.2 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 DUF2756 PF10956.3 CAM72376.1 - 3.6 7.8 9.6 7.2 6.9 6.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2756) D5_N PF08706.6 CAM72376.1 - 3.8 7.5 6.7 4.5 7.3 4.6 1.1 1 0 0 1 1 1 0 D5 N terminal like NAM-associated PF14303.1 CAM72376.1 - 4.3 7.6 20.0 5.3 7.3 13.9 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF737 PF05300.6 CAM72376.1 - 9.8 6.0 18.7 12 5.8 13.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) DSPc PF00782.15 CAM72377.2 - 3.7e-17 62.1 0.0 5.5e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CAM72377.2 - 0.0015 17.8 0.0 0.0022 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CAM72377.2 - 0.037 14.2 0.0 0.12 12.6 0.0 1.8 1 1 1 2 2 2 0 Tyrosine phosphatase family CDKN3 PF05706.7 CAM72377.2 - 0.059 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) zf-SNAP50_C PF12251.3 CAM72378.1 - 3.5e-55 186.4 0.2 4.7e-55 186.0 0.1 1.2 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal Katanin_con80 PF13925.1 CAM72379.1 - 3e-40 137.6 0.0 4.1e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 con80 domain of Katanin WD40 PF00400.27 CAM72379.1 - 1.1e-27 94.8 8.4 2e-10 40.1 0.1 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 CAM72379.1 - 0.0031 17.2 0.0 3.2 7.4 0.0 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CAM72379.1 - 0.029 12.5 1.0 0.24 9.4 0.0 2.3 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Adeno_PIX PF03955.9 CAM72380.1 - 0.0089 16.5 1.5 0.011 16.1 1.0 1.2 1 0 0 1 1 1 1 Adenovirus hexon-associated protein (IX) DnaG_DnaB_bind PF08278.6 CAM72380.1 - 0.038 14.1 0.2 0.046 13.9 0.2 1.0 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding Acetyltransf_11 PF13720.1 CAM72380.1 - 0.04 14.1 0.7 0.091 13.0 0.3 1.6 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 NEMO PF11577.3 CAM72380.1 - 0.04 13.6 6.1 0.34 10.7 2.2 2.1 1 1 1 2 2 2 0 NF-kappa-B essential modulator NEMO SCP-1 PF05483.7 CAM72380.1 - 0.054 11.2 0.5 0.06 11.1 0.4 1.0 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) DNA_repr_REX1B PF14966.1 CAM72380.1 - 0.063 13.6 0.2 0.075 13.4 0.1 1.1 1 0 0 1 1 1 0 DNA repair REX1-B FliJ PF02050.11 CAM72380.1 - 0.066 13.2 7.3 0.11 12.5 5.0 1.4 1 1 0 1 1 1 0 Flagellar FliJ protein CagE_TrbE_VirB PF03135.9 CAM72380.1 - 0.097 12.4 0.2 0.11 12.1 0.1 1.1 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system DUF137 PF02006.11 CAM72380.1 - 0.11 11.8 0.5 0.15 11.4 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF137 Viral_P18 PF04521.8 CAM72380.1 - 0.13 11.7 1.4 0.16 11.4 1.0 1.1 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein EMP24_GP25L PF01105.19 CAM72380.1 - 0.14 11.8 0.9 0.2 11.3 0.6 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Nnf1 PF03980.9 CAM72380.1 - 0.3 11.0 3.1 6.2 6.8 0.3 2.0 1 1 1 2 2 2 0 Nnf1 WXG100 PF06013.7 CAM72380.1 - 0.31 11.0 6.8 32 4.5 0.1 2.9 1 1 2 3 3 3 0 Proteins of 100 residues with WXG BMF PF15185.1 CAM72380.1 - 0.33 10.2 4.4 0.32 10.2 2.7 1.3 1 1 0 1 1 1 0 Bcl-2-modifying factor, apoptosis DUF1843 PF08898.5 CAM72380.1 - 0.42 10.7 3.7 2.7 8.0 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1843) SlyX PF04102.7 CAM72380.1 - 1.1 9.6 4.9 1.2 9.5 2.7 1.6 1 1 1 2 2 2 0 SlyX bZIP_2 PF07716.10 CAM72380.1 - 2.3 8.0 6.5 9.9 6.0 1.0 2.1 1 1 1 2 2 2 0 Basic region leucine zipper ParcG PF10274.4 CAM72381.1 - 6e-76 254.4 0.0 7.3e-76 254.1 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein Kinesin PF00225.18 CAM72382.1 - 1.2e-57 195.1 0.5 2.9e-57 193.9 0.3 1.6 1 1 0 1 1 1 1 Kinesin motor domain AAA_16 PF13191.1 CAM72382.1 - 0.0071 16.3 0.8 0.032 14.2 0.6 2.1 1 1 0 1 1 1 1 AAA ATPase domain PhoH PF02562.11 CAM72382.1 - 0.041 13.1 0.2 0.97 8.6 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein DUF87 PF01935.12 CAM72382.1 - 0.074 12.8 0.1 0.37 10.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_24 PF13479.1 CAM72382.1 - 0.14 11.7 0.1 0.33 10.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CAM72382.1 - 0.22 11.6 1.1 0.5 10.5 0.7 1.8 1 1 0 1 1 1 0 AAA domain HSP70 PF00012.15 CAM72383.1 - 1.5e-61 208.1 1.9 2.2e-60 204.2 1.3 2.2 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CAM72383.1 - 0.00045 18.9 0.0 0.0049 15.5 0.0 2.5 3 0 0 3 3 3 1 MreB/Mbl protein GCV_H PF01597.14 CAM72384.1 - 6.9e-37 125.8 0.8 7.4e-37 125.7 0.5 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 CAM72384.1 - 1.2e-07 31.2 0.7 2.1e-07 30.5 0.4 1.4 1 1 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.1 CAM72384.1 - 9.1e-05 22.1 0.2 0.00012 21.7 0.1 1.2 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain PTS_EIIA_1 PF00358.15 CAM72384.1 - 0.0027 17.2 0.1 0.0034 16.9 0.0 1.2 1 0 0 1 1 1 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Peptidase_M23 PF01551.17 CAM72384.1 - 0.0088 16.0 0.4 0.69 9.9 0.1 2.2 1 1 1 2 2 2 2 Peptidase family M23 Biotin_lipoyl_2 PF13533.1 CAM72384.1 - 0.026 14.1 0.7 2.9 7.6 0.0 2.4 1 1 1 2 2 2 0 Biotin-lipoyl like MS_channel PF00924.13 CAM72384.1 - 0.028 13.7 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel Gp_dh_N PF00044.19 CAM72386.1 - 6.1e-23 81.4 0.0 9.7e-23 80.7 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Gp_dh_C PF02800.15 CAM72386.1 - 1.1e-11 44.4 0.1 2e-11 43.5 0.0 1.5 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain ADH_zinc_N PF00107.21 CAM72386.1 - 0.047 13.2 0.2 0.34 10.4 0.0 2.1 2 0 0 2 2 2 0 Zinc-binding dehydrogenase DUF1761 PF08570.5 CAM72387.1 - 0.15 12.1 6.5 0.27 11.2 4.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1761) Pro_isomerase PF00160.16 CAM72388.1 - 4.4e-44 150.4 0.2 7.3e-44 149.6 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 CAM72388.1 - 1.8e-17 62.7 9.2 3.4e-09 36.2 0.8 2.2 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 CAM72388.1 - 1e-09 37.5 3.9 0.00028 20.5 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CAM72388.1 - 3.1e-08 32.8 2.9 0.0002 20.8 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 CAM72388.1 - 4.7e-05 23.5 0.8 0.79 10.3 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 CAM72388.1 - 5.1e-05 23.5 4.2 0.012 15.9 0.3 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 CAM72388.1 - 7.4e-05 22.6 3.8 0.01 15.7 0.7 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 CAM72388.1 - 0.00047 20.7 5.4 0.0015 19.1 1.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 CAM72388.1 - 0.0025 17.8 5.0 0.01 15.9 1.3 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 CAM72388.1 - 0.0033 17.9 0.5 0.088 13.4 0.2 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 CAM72388.1 - 0.0083 15.9 0.1 0.018 14.8 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF1586 PF07625.6 CAM72388.1 - 0.013 15.2 0.1 0.029 14.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1586) MIT PF04212.13 CAM72388.1 - 0.057 13.3 0.3 0.057 13.3 0.2 2.3 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_17 PF13431.1 CAM72388.1 - 0.093 12.9 0.1 1 9.7 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat SCAMP PF04144.8 CAM72390.1 - 5.1e-50 169.7 10.9 6.2e-50 169.5 7.6 1.0 1 0 0 1 1 1 1 SCAMP family DUF1129 PF06570.6 CAM72390.1 - 0.05 12.8 0.5 0.058 12.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) A_deaminase PF00962.17 CAM72391.1 - 3.6e-105 351.5 0.0 4.5e-80 269.0 0.0 2.3 2 0 0 2 2 2 2 Adenosine/AMP deaminase HNOBA PF07701.9 CAM72391.1 - 0.089 11.9 3.3 0.17 11.0 2.3 1.4 1 0 0 1 1 1 0 Heme NO binding associated His_Phos_1 PF00300.17 CAM72393.1 - 3.4e-13 49.9 0.0 1.2e-12 48.1 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) UBA PF00627.26 CAM72394.1 - 0.00013 21.7 0.0 0.00024 20.8 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Radical_SAM PF04055.16 CAM72394.1 - 0.0039 17.3 0.0 0.016 15.4 0.0 2.1 1 1 0 1 1 1 1 Radical SAM superfamily Rap1_C PF11626.3 CAM72394.1 - 0.041 13.7 0.2 0.36 10.7 0.1 2.5 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain NDUF_B8 PF05821.6 CAM72395.1 - 0.042 13.4 0.1 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Proteasome PF00227.21 CAM72396.1 - 7.6e-39 132.9 0.0 1.1e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CAM72396.1 - 1.3e-11 43.5 0.2 1.3e-11 43.5 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Porin_3 PF01459.17 CAM72397.1 - 0.13 11.5 1.8 0.18 11.1 1.3 1.3 1 0 0 1 1 1 0 Eukaryotic porin TPR_11 PF13414.1 CAM72399.1 - 3.1e-18 65.1 21.8 1.5e-16 59.8 5.7 3.1 2 2 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 CAM72399.1 - 1.6e-15 55.9 13.0 2.2e-06 27.0 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CAM72399.1 - 3.3e-11 42.1 24.2 2.3e-05 23.9 0.3 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 CAM72399.1 - 9.1e-07 28.6 5.7 1.1e-05 25.2 0.8 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CAM72399.1 - 7.9e-06 25.2 10.5 0.14 11.9 1.7 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 CAM72399.1 - 9.9e-06 25.4 11.3 0.00065 19.5 4.6 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat UPF0121 PF03661.8 CAM72399.1 - 1.2e-05 24.6 11.0 1.9e-05 24.0 7.6 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) TPR_16 PF13432.1 CAM72399.1 - 3.9e-05 24.1 3.6 3.9e-05 24.1 2.5 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 CAM72399.1 - 0.0012 18.4 3.9 1.5 8.8 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CAM72399.1 - 0.0042 17.3 1.0 0.0042 17.3 0.7 3.0 2 1 1 3 3 2 2 Tetratricopeptide repeat Apc3 PF12895.2 CAM72399.1 - 0.0046 17.0 6.9 0.01 15.9 4.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CAM72399.1 - 0.0056 16.5 0.2 0.022 14.5 0.1 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_3 PF07720.7 CAM72399.1 - 0.071 12.9 8.0 8.5 6.3 1.5 4.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 CAM72399.1 - 0.096 13.3 15.3 0.39 11.4 0.1 4.6 3 1 2 5 5 5 0 Tetratricopeptide repeat BTAD PF03704.12 CAM72399.1 - 0.18 12.1 4.7 9.9 6.4 1.1 2.8 2 1 0 2 2 2 0 Bacterial transcriptional activator domain TPR_10 PF13374.1 CAM72399.1 - 1.9 8.5 10.8 9.8 6.2 0.6 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Rad51 PF08423.6 CAM72400.1 - 7.6e-135 447.7 0.1 9.5e-135 447.4 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.16 CAM72400.1 - 2.9e-13 49.5 0.1 3.8e-13 49.1 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.1 CAM72400.1 - 8.6e-09 35.0 0.0 1.3e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 CAM72400.1 - 1.4e-07 30.8 0.1 2.4e-07 30.1 0.1 1.4 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.1 CAM72400.1 - 0.0017 18.4 0.2 0.0037 17.4 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain DnaB_C PF03796.10 CAM72400.1 - 0.12 11.2 0.2 0.2 10.5 0.1 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain MCM PF00493.18 CAM72402.1 - 6.9e-80 268.3 0.0 9.8e-80 267.8 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family AAA_5 PF07728.9 CAM72402.1 - 0.00012 21.8 0.0 0.0012 18.6 0.0 2.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CAM72402.1 - 0.00053 19.2 0.0 0.029 13.5 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CAM72402.1 - 0.023 14.3 0.0 0.063 12.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TTL PF03133.10 CAM72403.1 - 3.6e-74 249.3 0.0 5.6e-74 248.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 CAM72403.1 - 0.0062 15.3 0.2 0.028 13.2 0.0 1.9 2 0 0 2 2 2 1 YheC/D like ATP-grasp DUF241 PF03087.9 CAM72404.1 - 0.18 11.2 5.1 0.42 10.0 3.4 1.5 1 1 0 1 1 1 0 Arabidopsis protein of unknown function Wx5_PLAF3D7 PF09688.5 CAM72404.1 - 0.31 10.9 2.3 0.35 10.8 1.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (Wx5_PLAF3D7) Zip PF02535.17 CAM72404.1 - 4 6.3 5.6 6.4 5.6 3.9 1.3 1 1 0 1 1 1 0 ZIP Zinc transporter DNA_pol_viral_N PF00242.12 CAM72404.1 - 6.3 5.7 10.9 7.7 5.4 7.6 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Methyltransf_11 PF08241.7 CAM72407.1 - 2.1e-05 24.9 0.0 0.00077 19.9 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAM72407.1 - 0.00037 20.1 0.1 0.019 14.5 0.0 2.4 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAM72407.1 - 0.00045 19.9 0.0 0.00065 19.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAM72407.1 - 0.00081 19.9 0.0 0.0024 18.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAM72407.1 - 0.0021 18.5 0.0 0.0049 17.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CAM72407.1 - 0.16 11.0 0.0 0.32 10.0 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family BT1 PF03092.11 CAM72408.1 - 4.4e-164 546.3 11.6 5.1e-164 546.0 8.1 1.0 1 0 0 1 1 1 1 BT1 family MFS_1 PF07690.11 CAM72408.1 - 8.4e-05 21.4 12.8 8.4e-05 21.4 8.9 3.7 2 1 1 3 3 3 2 Major Facilitator Superfamily AAA_28 PF13521.1 CAM72409.1 - 0.00017 21.6 0.0 0.00026 21.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CAM72409.1 - 0.00072 18.7 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 CAM72409.1 - 0.00083 20.1 0.0 0.0016 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CAM72409.1 - 0.0012 18.8 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 CAM72409.1 - 0.0014 18.5 0.0 0.0027 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 CAM72409.1 - 0.0023 17.6 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_18 PF13238.1 CAM72409.1 - 0.0054 17.0 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CAM72409.1 - 0.025 14.4 0.0 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 CAM72409.1 - 0.035 14.3 0.0 0.063 13.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CAM72409.1 - 0.037 12.7 0.0 0.055 12.1 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 CAM72409.1 - 0.075 13.2 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.18 CAM72410.1 - 8.3e-05 22.5 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 CAM72410.1 - 0.077 12.9 0.0 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 CAM72410.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family FeoB_N PF02421.13 CAM72410.1 - 0.14 11.3 0.0 0.39 10.0 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF830 PF05708.7 CAM72411.1 - 0.086 12.8 0.0 2.4 8.1 0.0 2.3 2 0 0 2 2 2 0 Orthopoxvirus protein of unknown function (DUF830) Pkinase PF00069.20 CAM72412.1 - 8e-54 182.5 0.0 1.2e-53 181.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM72412.1 - 7.8e-36 123.4 0.0 1.2e-35 122.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM72412.1 - 7.2e-09 35.0 0.0 3.3e-08 32.8 0.0 1.8 1 1 1 2 2 2 1 Kinase-like PH PF00169.24 CAM72412.1 - 2.9e-07 30.6 0.0 5.7e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 PH domain Mcp5_PH PF12814.2 CAM72412.1 - 0.0007 19.5 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology zf-CCCH PF00642.19 CAM72413.1 - 7.6e-05 22.2 0.4 7.6e-05 22.2 0.3 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MMR_HSR1 PF01926.18 CAM72414.1 - 2e-12 47.0 0.0 1.8e-10 40.7 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 CAM72414.1 - 4e-05 22.8 0.0 7.8e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CAM72414.1 - 0.0047 17.0 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.18 CAM72414.1 - 0.0094 15.7 0.8 2.1 8.1 0.0 3.0 2 1 1 3 3 3 1 Dynamin family FeoB_N PF02421.13 CAM72414.1 - 0.02 14.1 0.1 0.052 12.8 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B Septin PF00735.13 CAM72414.1 - 0.15 11.0 0.0 0.31 10.0 0.0 1.4 1 0 0 1 1 1 0 Septin V-SNARE PF05008.10 CAM72415.1 - 0.0053 16.9 2.8 0.0095 16.0 0.8 2.5 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus DUF4593 PF15263.1 CAM72415.1 - 0.038 13.8 0.2 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4593) Shugoshin_N PF07558.6 CAM72415.1 - 0.19 11.4 1.4 5.2 6.8 0.1 2.6 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF4407 PF14362.1 CAM72415.1 - 0.95 8.3 9.2 0.058 12.3 0.7 2.2 2 1 0 3 3 3 0 Domain of unknown function (DUF4407) DUF4201 PF13870.1 CAM72415.1 - 2.4 7.5 12.8 0.07 12.5 2.8 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) HAUS-augmin3 PF14932.1 CAM72415.1 - 5.3 6.1 17.1 0.29 10.2 4.2 2.4 2 1 1 3 3 3 0 HAUS augmin-like complex subunit 3 Methyltransf_4 PF02390.12 CAM72416.1 - 2.1e-36 124.8 0.0 2.5e-36 124.5 0.0 1.0 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 CAM72416.1 - 2.8e-05 23.7 0.0 0.00023 20.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAM72416.1 - 2.8e-05 24.6 0.0 5.3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAM72416.1 - 0.0073 16.7 0.0 0.027 14.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Glycos_transf_1 PF00534.15 CAM72418.1 - 1.3e-19 70.2 0.0 1.8e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CAM72418.1 - 1.8e-08 34.6 0.0 3.5e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CAM72418.1 - 0.0015 18.7 0.0 0.0045 17.2 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 HALZ PF02183.13 CAM72419.1 - 2.2e-06 27.2 0.9 2.2e-06 27.2 0.7 1.7 2 0 0 2 2 2 1 Homeobox associated leucine zipper DivIVA PF05103.8 CAM72419.1 - 0.0052 16.8 0.4 0.0052 16.8 0.2 1.7 2 0 0 2 2 2 1 DivIVA protein Kinetocho_Slk19 PF12709.2 CAM72419.1 - 0.0072 16.3 2.0 0.0084 16.1 1.4 1.2 1 0 0 1 1 1 1 Central kinetochore-associated Rootletin PF15035.1 CAM72419.1 - 0.0089 16.0 0.7 0.0094 15.9 0.5 1.1 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Prp19 PF08606.6 CAM72419.1 - 0.01 15.5 0.5 0.15 11.8 0.1 2.1 2 0 0 2 2 2 0 Prp19/Pso4-like HalX PF08663.5 CAM72419.1 - 0.012 15.5 0.5 0.025 14.5 0.1 1.6 2 0 0 2 2 2 0 HalX domain DivIC PF04977.10 CAM72419.1 - 0.022 14.2 0.6 0.022 14.2 0.4 1.8 2 0 0 2 2 2 0 Septum formation initiator Urb2 PF10441.4 CAM72419.1 - 0.033 13.7 0.1 0.035 13.6 0.1 1.1 1 0 0 1 1 1 0 Urb2/Npa2 family DUF1640 PF07798.6 CAM72419.1 - 0.049 13.6 0.2 0.058 13.4 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Dpy-30 PF05186.8 CAM72419.1 - 0.051 13.0 0.2 0.14 11.7 0.1 1.7 1 1 0 1 1 1 0 Dpy-30 motif K-box PF01486.12 CAM72419.1 - 0.053 13.3 0.7 0.084 12.6 0.0 1.6 2 0 0 2 2 2 0 K-box region bZIP_1 PF00170.16 CAM72419.1 - 0.068 13.1 0.2 0.068 13.1 0.1 1.7 2 1 0 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.10 CAM72419.1 - 0.074 12.8 1.1 0.074 12.8 0.7 1.7 2 0 0 2 2 2 0 Basic region leucine zipper SinI PF08671.5 CAM72419.1 - 0.1 12.0 0.1 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 Anti-repressor SinI CCDC155 PF14662.1 CAM72419.1 - 0.13 11.8 2.2 0.15 11.6 0.1 1.8 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 AvrPto PF11592.3 CAM72419.1 - 0.14 11.9 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Central core of the bacterial effector protein AvrPto DUF972 PF06156.8 CAM72419.1 - 0.25 11.6 1.4 1.1 9.6 0.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) WD40 PF00400.27 CAM72420.1 - 1.3e-16 59.7 11.3 1.5e-06 27.8 0.1 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat AD PF09793.4 CAM72422.1 - 0.12 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Anticodon-binding domain TGS PF02824.16 CAM72424.1 - 9e-23 79.8 0.0 1.9e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 CAM72424.1 - 9.4e-17 61.0 0.0 2.1e-16 59.9 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CAM72424.1 - 5.2e-10 38.8 0.0 9.6e-10 37.9 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CAM72424.1 - 0.0002 21.2 0.2 0.063 13.0 0.0 2.4 1 1 0 2 2 2 2 Dynamin family Miro PF08477.8 CAM72424.1 - 0.00032 21.1 0.0 0.0011 19.4 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein AIG1 PF04548.11 CAM72424.1 - 0.056 12.5 0.0 0.096 11.7 0.0 1.4 1 0 0 1 1 1 0 AIG1 family SAC3_GANP PF03399.11 CAM72425.1 - 3.5e-30 105.0 0.2 5.5e-30 104.4 0.1 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DUF605 PF04652.11 CAM72425.1 - 0.31 10.3 8.8 0.77 9.0 6.1 1.4 1 1 0 1 1 1 0 Vta1 like FMN_dh PF01070.13 CAM72426.1 - 4.2e-35 121.2 0.0 6.3e-22 77.9 0.0 2.1 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.20 CAM72426.1 - 1.6e-06 27.3 1.1 0.00072 18.5 0.3 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 CAM72426.1 - 2.3e-05 23.5 0.9 0.00013 21.0 0.6 1.9 1 1 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 CAM72426.1 - 0.0037 16.4 0.1 0.0059 15.7 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 CAM72426.1 - 0.23 10.6 1.2 0.67 9.1 0.1 2.0 2 1 1 3 3 3 0 Histidine biosynthesis protein Ank_2 PF12796.2 CAM72427.1 - 3.3e-13 49.7 0.0 4.2e-07 30.2 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CAM72427.1 - 3.8e-08 32.7 0.0 6.9e-06 25.6 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 CAM72427.1 - 1.2e-06 28.8 0.0 0.05 14.1 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Dynein_heavy PF03028.10 CAM72427.1 - 1.4e-06 26.6 0.0 1.9e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor Ank_3 PF13606.1 CAM72427.1 - 0.0013 18.8 0.0 0.11 12.8 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 CAM72427.1 - 0.0083 16.3 0.0 0.066 13.4 0.0 2.4 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Aa_trans PF01490.13 CAM72428.1 - 6.9e-56 189.4 32.7 7.7e-56 189.3 22.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Pkinase PF00069.20 CAM72429.1 - 1.3e-67 227.7 0.0 1.6e-67 227.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM72429.1 - 8.6e-30 103.6 0.0 2.6e-29 102.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM72429.1 - 4e-05 22.7 0.0 0.0002 20.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CAM72429.1 - 0.028 14.1 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CAM72429.1 - 0.036 12.8 0.0 0.062 12.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 CAM72429.1 - 0.048 12.7 0.1 0.097 11.7 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DNA_ligase_A_N PF04675.9 CAM72430.1 - 0.047 13.5 0.1 0.099 12.4 0.1 1.5 1 0 0 1 1 1 0 DNA ligase N terminus RRM_1 PF00076.17 CAM72432.2 - 8.2e-79 259.2 5.3 6.1e-21 73.8 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM72432.2 - 7.6e-52 173.1 3.2 2.3e-15 56.3 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM72432.2 - 4.5e-35 119.2 2.3 2.9e-10 39.8 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 CAM72432.2 - 3.1e-21 74.8 0.2 1.6e-19 69.3 0.0 2.6 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.6 CAM72432.2 - 2.1e-06 27.5 1.5 0.13 12.1 0.2 4.2 4 0 0 4 4 4 2 RNA binding motif Nup35_RRM_2 PF14605.1 CAM72432.2 - 0.0004 20.1 0.3 3.8 7.3 0.0 4.2 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif DUF4523 PF15023.1 CAM72432.2 - 0.014 14.9 0.0 2.6 7.5 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4523) Limkain-b1 PF11608.3 CAM72432.2 - 0.028 14.1 0.5 6.4 6.6 0.0 3.4 4 0 0 4 4 4 0 Limkain b1 PAT1 PF09770.4 CAM72432.2 - 9 4.3 13.2 12 3.9 9.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1484 PF07363.6 CAM72434.1 - 0.083 13.2 1.1 1.2 9.5 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1484) TF_Zn_Ribbon PF08271.7 CAM72435.1 - 0.097 12.0 0.5 0.3 10.4 0.3 1.8 1 0 0 1 1 1 0 TFIIB zinc-binding EF-hand_6 PF13405.1 CAM72435.1 - 0.14 12.0 1.3 0.19 11.6 0.1 1.9 2 0 0 2 2 2 0 EF-hand domain IFT57 PF10498.4 CAM72436.1 - 0.0096 14.7 3.0 0.011 14.5 2.1 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Seryl_tRNA_N PF02403.17 CAM72436.1 - 0.013 15.5 1.3 0.024 14.6 0.9 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain V_ATPase_I PF01496.14 CAM72436.1 - 0.028 12.2 2.0 0.038 11.8 1.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CLP_protease PF00574.18 CAM72436.1 - 0.034 13.8 0.2 1.5 8.4 0.1 2.1 2 0 0 2 2 2 0 Clp protease Jnk-SapK_ap_N PF09744.4 CAM72436.1 - 0.043 13.8 3.5 0.13 12.2 2.5 1.8 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Occludin_ELL PF07303.8 CAM72436.1 - 0.068 13.9 1.4 0.15 12.7 0.9 1.6 1 0 0 1 1 1 0 Occludin homology domain Rop-like PF05082.8 CAM72436.1 - 0.068 12.6 0.0 0.21 11.0 0.0 1.8 1 0 0 1 1 1 0 Rop-like DUF1664 PF07889.7 CAM72436.1 - 0.07 12.9 0.8 0.13 12.0 0.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Spc7 PF08317.6 CAM72436.1 - 0.074 11.6 4.5 0.1 11.2 3.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein GLE1 PF07817.8 CAM72436.1 - 0.11 11.4 3.0 6.2 5.6 0.0 2.1 2 0 0 2 2 2 0 GLE1-like protein DUF948 PF06103.6 CAM72436.1 - 0.11 12.3 0.9 6 6.7 0.3 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.7 CAM72436.1 - 0.37 10.5 5.3 1.1 9.0 3.5 1.8 1 1 1 2 2 2 0 Laminin Domain II NYD-SP28_assoc PF14775.1 CAM72436.1 - 0.78 9.4 7.9 2.1 8.1 3.1 2.8 1 1 1 2 2 2 0 Sperm tail C-terminal domain RNase_Zc3h12a PF11977.3 CAM72437.1 - 0.034 13.9 0.1 0.35 10.7 0.0 2.2 2 0 0 2 2 2 0 Zc3h12a-like Ribonuclease NYN domain Ribosomal_L37e PF01907.14 CAM72438.1 - 1.1e-22 79.6 8.0 1.8e-22 78.8 5.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e zinc_ribbon_6 PF14599.1 CAM72438.1 - 0.046 13.5 0.6 0.07 12.9 0.4 1.3 1 0 0 1 1 1 0 Zinc-ribbon DZR PF12773.2 CAM72438.1 - 0.093 12.5 0.8 0.15 11.8 0.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon PseudoU_synth_2 PF00849.17 CAM72439.1 - 9.6e-25 87.3 0.0 1.6e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase ALF PF03752.8 CAM72439.1 - 0.32 10.9 6.9 0.82 9.5 3.9 2.5 1 1 1 2 2 2 0 Short repeats of unknown function HECT PF00632.20 CAM72440.1 - 1.4e-40 139.3 0.1 2.7e-40 138.4 0.1 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.23 CAM72440.1 - 2.7e-12 46.8 0.4 2.8e-05 24.2 0.0 4.5 4 0 0 4 4 4 3 SPRY domain YL1 PF05764.8 CAM72440.1 - 4.4 6.8 2.9 6.8 6.2 2.0 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Aa_trans PF01490.13 CAM72441.1 - 6.9e-53 179.5 32.3 8.2e-53 179.3 22.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CAM72441.1 - 7.4e-07 28.3 18.7 7.4e-07 28.3 12.9 2.0 2 1 1 3 3 3 1 Tryptophan/tyrosine permease family DAGK_acc PF00609.14 CAM72442.1 - 2e-37 128.8 0.0 2.7e-37 128.3 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 CAM72442.1 - 9.4e-13 47.7 0.0 1.4e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.16 CAM72442.1 - 0.017 13.9 0.0 0.03 13.1 0.0 1.3 1 0 0 1 1 1 0 ATP-NAD kinase PSP1 PF04468.7 CAM72444.1 - 4.8e-16 58.5 1.3 8.2e-16 57.7 0.9 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region PE_PPE_C PF12484.3 CAM72444.1 - 0.0056 17.5 4.4 0.012 16.4 3.0 1.6 1 0 0 1 1 1 1 Polymorphic PE/PPE proteins C terminal PAP2_C PF14360.1 CAM72445.1 - 8.3e-20 70.8 7.6 8.3e-20 70.8 5.3 2.6 3 0 0 3 3 3 1 PAP2 superfamily C-terminal Sugar_tr PF00083.19 CAM72450.1 - 3.6e-105 352.1 35.0 3.7e-104 348.8 24.3 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAM72450.1 - 7.3e-15 54.5 38.1 1e-13 50.7 24.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CAM72450.1 - 0.0018 16.7 30.7 0.015 13.6 0.0 3.2 2 1 1 3 3 3 2 MFS/sugar transport protein DUF2217 PF10265.4 CAM72451.2 - 5.8 5.5 10.2 9.3 4.8 7.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Tad PF13400.1 CAM72452.1 - 0.27 11.3 8.8 1.6 8.8 6.1 2.4 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like DUF4250 PF14056.1 CAM72452.1 - 4.4 7.1 6.0 3.8 7.2 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4250) Pkinase PF00069.20 CAM72453.1 - 3.5e-57 193.5 0.0 6.5e-57 192.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM72453.1 - 5.7e-36 123.9 0.0 9.4e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM72453.1 - 2.5e-10 39.8 0.0 8.6e-08 31.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 CAM72453.1 - 4.2e-05 23.3 1.2 0.11 12.2 0.0 3.9 3 1 1 4 4 4 2 Phosphotransferase enzyme family zf-C2H2_jaz PF12171.3 CAM72453.1 - 0.0028 17.7 0.9 0.021 14.9 0.1 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Seadorna_VP7 PF07387.6 CAM72453.1 - 0.021 13.6 0.0 0.039 12.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 CAM72453.1 - 0.04 12.9 0.0 0.082 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IBR PF01485.16 CAM72453.1 - 0.48 10.3 6.4 1.2 9.0 4.3 1.7 1 1 0 1 1 1 0 IBR domain ZZ PF00569.12 CAM72453.1 - 0.57 9.7 8.9 2.4 7.7 6.2 2.1 1 1 0 1 1 1 0 Zinc finger, ZZ type C1_3 PF07649.7 CAM72453.1 - 0.61 10.1 10.8 0.35 10.9 5.3 2.1 2 0 0 2 2 2 0 C1-like domain FYVE_2 PF02318.11 CAM72453.1 - 3.1 7.7 10.0 0.35 10.7 3.4 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger Ubie_methyltran PF01209.13 CAM72454.1 - 2.1e-113 377.2 0.0 2.4e-113 377.0 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 CAM72454.1 - 6.3e-16 58.6 0.0 1.2e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAM72454.1 - 5.7e-12 45.4 0.0 7.4e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAM72454.1 - 1.5e-11 44.5 0.0 2.7e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAM72454.1 - 1.3e-07 31.4 0.0 1.8e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAM72454.1 - 2.1e-07 31.3 0.0 3.2e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAM72454.1 - 0.0005 20.6 0.0 0.00097 19.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 CAM72454.1 - 0.0013 18.3 0.0 0.039 13.5 0.0 2.4 2 1 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_2 PF00891.13 CAM72454.1 - 0.1 11.7 0.1 4.7 6.3 0.0 2.1 2 0 0 2 2 2 0 O-methyltransferase Pkinase PF00069.20 CAM72456.1 - 0.14 11.2 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain GST_C_2 PF13410.1 CAM72458.1 - 2.5e-10 40.0 0.1 9.1e-10 38.3 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CAM72458.1 - 2e-06 28.1 0.0 6.5e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CAM72458.1 - 0.036 14.0 0.0 0.11 12.4 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Sugar_tr PF00083.19 CAM72459.2 - 6.4e-105 351.3 33.4 5.9e-104 348.1 23.2 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAM72459.2 - 6.6e-15 54.6 37.5 1.2e-13 50.5 24.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CAM72459.2 - 0.003 16.0 30.5 0.015 13.6 0.1 3.2 2 1 1 3 3 3 2 MFS/sugar transport protein DnaJ PF00226.26 CAM72460.1 - 7e-28 96.1 5.1 1.1e-27 95.5 3.5 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CAM72460.1 - 3.2e-24 84.6 0.3 1.5e-21 76.1 0.1 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain Peptidase_M32 PF02074.10 CAM72461.1 - 4e-60 203.8 0.0 4.8e-60 203.6 0.0 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase Ras PF00071.17 CAM72462.1 - 6.2e-47 158.9 1.5 1.1e-46 158.1 0.5 1.8 2 0 0 2 2 2 1 Ras family Miro PF08477.8 CAM72462.1 - 8.2e-15 55.3 0.0 1.8e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAM72462.1 - 2.4e-06 26.8 0.0 3.2e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CAM72462.1 - 0.00085 19.2 0.1 0.002 18.0 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CAM72462.1 - 0.006 15.8 0.0 1.9 7.7 0.0 2.5 2 0 0 2 2 2 2 Ferrous iron transport protein B Gtr1_RagA PF04670.7 CAM72462.1 - 0.021 13.9 0.0 0.036 13.1 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region HECT PF00632.20 CAM72464.2 - 1.2e-55 188.8 0.0 2e-55 188.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.23 CAM72464.2 - 2e-40 137.7 0.0 1.1e-17 64.2 0.0 4.1 4 1 0 4 4 4 3 SPRY domain Laminin_G_3 PF13385.1 CAM72464.2 - 1.9e-18 67.1 0.1 1.7e-08 34.8 0.0 4.2 5 0 0 5 5 5 2 Concanavalin A-like lectin/glucanases superfamily APP_E2 PF12925.2 CAM72464.2 - 9 5.8 4.8 4.7 6.7 1.3 1.9 2 0 0 2 2 2 0 E2 domain of amyloid precursor protein CAF1 PF04857.15 CAM72467.1 - 8.3e-38 130.2 0.0 1.2e-37 129.7 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease DUF2962 PF11176.3 CAM72468.1 - 1.3e-32 112.4 0.2 1.3e-32 112.4 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2962) Calci_bind_CcbP PF11535.3 CAM72468.1 - 0.099 12.9 1.8 0.44 10.8 0.1 2.3 2 0 0 2 2 2 0 Calcium binding RabGAP-TBC PF00566.13 CAM72469.1 - 1e-20 74.1 0.4 1.5e-20 73.5 0.3 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Nucleoporin_FG PF13634.1 CAM72469.1 - 2.2e-05 24.6 26.1 3.8e-05 23.8 18.1 1.2 1 0 0 1 1 1 1 Nucleoporin FG repeat region Takusan PF04822.8 CAM72469.1 - 0.17 11.6 0.9 9.3 6.0 0.0 3.2 3 0 0 3 3 3 0 Takusan DUF1126 PF06565.7 CAM72470.1 - 6.1e-37 124.7 0.2 6.5e-13 47.9 0.0 3.8 3 0 0 3 3 3 3 Repeat of unknown function (DUF1126) EF-hand_8 PF13833.1 CAM72470.1 - 4.9e-06 26.0 0.2 0.027 14.0 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.1 CAM72470.1 - 0.00042 20.3 0.2 0.0043 17.1 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CAM72470.1 - 0.12 12.3 0.3 23 5.2 0.0 3.9 4 0 0 4 4 4 0 EF-hand domain EF-hand_1 PF00036.27 CAM72470.1 - 0.12 11.6 0.6 0.63 9.4 0.1 2.4 2 0 0 2 2 2 0 EF hand MTHFR PF02219.12 CAM72471.1 - 1.5e-89 299.8 0.0 1.9e-89 299.5 0.0 1.0 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Toxin_22 PF08092.6 CAM72471.1 - 0.13 12.1 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 Magi peptide toxin family Ribosomal_S8e PF01201.17 CAM72472.1 - 1.7e-35 122.0 11.1 1.4e-34 119.1 7.7 2.1 1 1 0 1 1 1 1 Ribosomal protein S8e DUF3746 PF12562.3 CAM72472.1 - 0.12 12.2 0.7 0.69 9.8 0.5 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3746) DUF4496 PF14908.1 CAM72473.1 - 2.9e-11 43.4 0.0 7.7e-11 42.0 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4496) TB2_DP1_HVA22 PF03134.14 CAM72474.1 - 0.028 14.1 1.8 0.042 13.6 1.3 1.3 1 0 0 1 1 1 0 TB2/DP1, HVA22 family Sec23_trunk PF04811.10 CAM72475.1 - 5.1e-50 170.1 0.0 8e-50 169.4 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CAM72475.1 - 5.7e-28 96.3 0.1 1.4e-27 95.0 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 CAM72475.1 - 8.7e-21 74.2 0.9 8.7e-21 74.2 0.6 2.3 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 CAM72475.1 - 1.2e-13 50.3 1.1 3.1e-13 49.0 0.8 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 CAM72475.1 - 1.3e-05 24.7 0.4 3.8e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Gelsolin repeat DUF1539 PF07560.6 CAM72476.1 - 0.027 14.3 0.5 0.32 10.8 0.1 2.1 1 1 0 2 2 2 0 Domain of Unknown Function (DUF1539) DUF4231 PF14015.1 CAM72476.1 - 0.36 10.8 2.4 9.6 6.2 1.7 2.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) His_Phos_2 PF00328.17 CAM72478.1 - 1.2e-15 57.7 1.4 1.3e-14 54.2 1.0 2.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Pkinase PF00069.20 CAM72480.1 - 1.8e-64 217.4 0.0 2.2e-64 217.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM72480.1 - 7.9e-26 90.6 0.0 1.1e-25 90.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM72480.1 - 2.6e-09 36.4 0.1 5.7e-09 35.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 CAM72480.1 - 0.00015 20.8 0.6 0.00041 19.4 0.4 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CAM72480.1 - 0.0065 16.2 0.4 0.19 11.4 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 CAM72480.1 - 0.055 12.8 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family His_Phos_2 PF00328.17 CAM72481.1 - 9.2e-27 94.2 0.8 4.4e-25 88.7 0.5 2.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) UFD1 PF03152.9 CAM72482.1 - 5.5e-52 175.4 0.0 6.6e-52 175.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 PCI PF01399.22 CAM72484.1 - 0.0022 18.3 0.0 0.0044 17.3 0.0 1.5 1 0 0 1 1 1 1 PCI domain SdpI PF13630.1 CAM72486.1 - 0.0076 15.9 3.5 0.0076 15.9 2.5 2.1 2 0 0 2 2 2 1 SdpI/YhfL protein family MFS_1 PF07690.11 CAM72486.1 - 0.01 14.5 6.5 0.013 14.2 4.5 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily 7TMR-DISM_7TM PF07695.6 CAM72486.1 - 0.35 10.5 13.2 0.73 9.4 9.1 1.5 1 1 0 1 1 1 0 7TM diverse intracellular signalling 2TM PF13239.1 CAM72486.1 - 3.6 7.7 7.1 1.4 9.0 3.2 1.7 1 1 1 2 2 2 0 2TM domain DUF904 PF06005.7 CAM72487.1 - 0.23 11.7 2.6 0.19 12.0 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Myb_DNA-binding PF00249.26 CAM72488.1 - 2.6e-05 24.1 0.0 6.5e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF1963 PF09234.5 CAM72488.1 - 0.21 11.8 3.9 0.4 10.8 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1963) DLH PF01738.13 CAM72489.1 - 2.4e-22 79.3 0.0 2.8e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 CAM72489.1 - 4.7e-07 29.6 0.0 6e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CAM72489.1 - 9.4e-07 28.9 0.6 1.4e-06 28.3 0.4 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 CAM72489.1 - 0.048 13.3 0.0 0.068 12.8 0.0 1.3 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Cys_rich_CWC PF14375.1 CAM72489.1 - 0.15 12.0 1.4 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 Cysteine-rich CWC PCMT PF01135.14 CAM72490.2 - 3.3e-47 160.7 0.0 4.3e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 CAM72490.2 - 2.2e-07 31.4 0.0 3.7e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF4491 PF14898.1 CAM72490.2 - 0.00016 21.7 0.2 0.095 12.8 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4491) Methyltransf_32 PF13679.1 CAM72490.2 - 0.00057 19.5 0.0 0.00081 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAM72490.2 - 0.0017 17.9 0.0 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CAM72490.2 - 0.0062 16.5 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 CAM72490.2 - 0.02 15.6 0.0 0.032 15.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 CAM72490.2 - 0.069 12.8 0.0 0.087 12.5 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Peptidase_S9_N PF02897.10 CAM72491.1 - 8.2e-100 334.2 5.8 1.1e-99 333.7 4.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 CAM72491.1 - 9.1e-66 221.1 0.0 1.6e-65 220.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 CAM72491.1 - 0.00016 21.1 0.0 0.0003 20.3 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.8 CAM72491.1 - 0.015 14.9 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF4019 PF13211.1 CAM72491.1 - 0.015 15.5 0.2 6.6 7.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4019) Abhydrolase_1 PF00561.15 CAM72491.1 - 0.072 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold OSCP PF00213.13 CAM72492.1 - 9.8e-07 28.7 0.1 4.7e-06 26.5 0.1 2.0 1 1 0 1 1 1 1 ATP synthase delta (OSCP) subunit Adaptin_N PF01602.15 CAM72493.1 - 3.1e-107 359.0 4.2 3.9e-107 358.7 2.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CAM72493.1 - 1.4e-18 67.3 0.3 4e-18 65.8 0.2 1.8 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CAM72493.1 - 6.2e-14 52.0 0.0 9.5e-08 32.2 0.0 4.7 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.17 CAM72493.1 - 2.4e-07 30.2 4.5 0.027 14.5 0.0 5.5 5 0 0 5 5 5 1 HEAT repeat VHS PF00790.14 CAM72493.1 - 0.0036 16.9 0.5 0.0092 15.6 0.1 1.9 2 0 0 2 2 2 1 VHS domain CAP18_C PF12153.3 CAM72493.1 - 0.027 14.1 1.2 0.059 13.0 0.8 1.6 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) DUF3384 PF11864.3 CAM72493.1 - 0.032 12.7 0.1 0.058 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) DUF2435 PF10363.4 CAM72493.1 - 0.052 13.4 0.0 4.5 7.2 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) HEAT_EZ PF13513.1 CAM72493.1 - 0.14 12.6 5.3 2.4 8.7 0.0 4.8 4 1 1 5 5 5 0 HEAT-like repeat NIF PF03031.13 CAM72494.1 - 9e-32 109.9 0.0 1.3e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase AFG1_ATPase PF03969.11 CAM72495.1 - 8.1e-56 189.3 1.6 5.5e-54 183.3 0.0 2.8 2 1 0 3 3 3 2 AFG1-like ATPase AAA_16 PF13191.1 CAM72495.1 - 0.022 14.7 1.8 0.25 11.3 0.4 3.0 2 1 0 2 2 2 0 AAA ATPase domain BLIP PF07467.6 CAM72495.1 - 0.054 13.1 0.1 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase inhibitor (BLIP) NACHT PF05729.7 CAM72495.1 - 0.073 12.7 0.1 0.32 10.6 0.0 2.0 1 1 1 2 2 2 0 NACHT domain DUF1289 PF06945.8 CAM72495.1 - 3.7 7.0 6.5 0.19 11.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) DUF2042 PF09743.4 CAM72496.1 - 3.3e-86 288.9 0.0 4.9e-86 288.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2042) 4HBT PF03061.17 CAM72497.1 - 1.8e-06 27.9 0.0 2.8e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 CAM72497.1 - 4.4e-05 23.4 0.0 5.9e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) SET PF00856.23 CAM72498.1 - 1.6e-06 28.5 0.0 0.0021 18.4 0.0 2.4 1 1 0 1 1 1 1 SET domain Aa_trans PF01490.13 CAM72499.1 - 4.9e-41 140.5 33.4 5.8e-41 140.3 23.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2453 PF10507.4 CAM72500.1 - 5.5e-44 148.4 5.3 1.1e-43 147.4 3.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2453) EF-hand_1 PF00036.27 CAM72500.1 - 1.9e-07 29.8 0.3 0.0024 17.0 0.0 3.3 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.1 CAM72500.1 - 8.9e-06 25.7 1.5 0.046 13.8 0.1 2.9 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 CAM72500.1 - 6.6e-05 22.4 0.4 0.12 12.3 0.0 3.8 4 0 0 4 4 4 1 EF-hand domain EF-hand_5 PF13202.1 CAM72500.1 - 0.035 13.4 0.2 1.6 8.2 0.0 3.1 3 0 0 3 3 3 0 EF hand AA_permease_2 PF13520.1 CAM72500.1 - 0.15 10.6 5.0 5.9 5.3 0.0 2.2 2 0 0 2 2 2 0 Amino acid permease GHMP_kinases_N PF00288.21 CAM72500.1 - 5.2 7.2 9.4 0.17 11.9 1.9 2.0 2 0 0 2 2 2 0 GHMP kinases N terminal domain RNA_lig_T4_1 PF09511.5 CAM72502.1 - 1e-14 54.5 0.0 1.8e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 RNA ligase AAA_33 PF13671.1 CAM72502.1 - 6.8e-12 45.4 0.1 1.8e-11 44.0 0.1 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 CAM72502.1 - 4.4e-05 23.1 0.0 0.00013 21.6 0.0 1.8 1 0 0 1 1 1 1 NACHT domain 6PF2K PF01591.13 CAM72502.1 - 4.4e-05 22.6 0.0 7.4e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_18 PF13238.1 CAM72502.1 - 0.0001 22.6 0.0 0.00021 21.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 CAM72502.1 - 0.00016 21.3 0.0 0.00041 20.0 0.0 1.8 1 0 0 1 1 1 1 Adenylylsulphate kinase KTI12 PF08433.5 CAM72502.1 - 0.00049 19.3 0.0 0.00086 18.5 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 CAM72502.1 - 0.0018 19.0 0.0 0.0043 17.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CAM72502.1 - 0.0018 18.5 0.0 0.0095 16.2 0.0 2.2 2 0 0 2 2 2 1 ABC transporter AAA_19 PF13245.1 CAM72502.1 - 0.0026 17.4 0.5 0.12 12.1 0.1 3.3 2 0 0 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 CAM72502.1 - 0.0038 16.3 0.0 0.0091 15.1 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin RuvB_N PF05496.7 CAM72502.1 - 0.014 14.4 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CAM72502.1 - 0.029 14.5 0.0 0.077 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CAM72502.1 - 0.033 13.5 0.7 0.13 11.6 0.3 2.1 1 1 1 2 2 2 0 AAA domain tRNA_lig_CPD PF08302.6 CAM72502.1 - 0.034 13.3 0.0 0.056 12.6 0.0 1.3 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain AAA_5 PF07728.9 CAM72502.1 - 0.038 13.7 0.0 0.087 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CPT PF07931.7 CAM72502.1 - 0.064 12.8 0.1 1.5 8.4 0.0 2.6 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein TIP49 PF06068.8 CAM72502.1 - 0.3 9.7 0.0 0.52 8.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Ank_5 PF13857.1 CAM72503.1 - 0.039 14.2 0.0 0.29 11.4 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) EVE PF01878.13 CAM72504.1 - 5.2e-53 178.9 0.3 6.8e-53 178.5 0.2 1.1 1 0 0 1 1 1 1 EVE domain Phytoreo_S7 PF07236.6 CAM72504.1 - 0.062 11.6 0.0 0.079 11.2 0.0 1.1 1 0 0 1 1 1 0 Phytoreovirus S7 protein Bromodomain PF00439.20 CAM72505.1 - 2.4e-16 59.4 0.0 4e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Bromodomain Nucleoporin_N PF08801.6 CAM72506.1 - 2.7e-45 154.8 0.0 4.3e-45 154.2 0.0 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.9 CAM72506.1 - 8.3e-07 27.9 3.1 1.5e-05 23.7 2.1 2.1 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal LRR_4 PF12799.2 CAM72507.1 - 0.00057 19.4 0.0 0.036 13.7 0.0 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) Cpn60_TCP1 PF00118.19 CAM72508.1 - 5.4e-138 460.6 8.3 6.2e-138 460.4 5.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family zf-C2H2_6 PF13912.1 CAM72510.1 - 3.7e-05 23.4 9.3 0.00021 21.0 0.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CAM72510.1 - 0.0029 17.8 10.5 0.033 14.5 1.7 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.2 CAM72510.1 - 0.0041 17.2 6.8 0.38 11.0 0.5 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 CAM72510.1 - 0.0067 16.6 7.7 0.043 14.1 0.5 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 CAM72510.1 - 0.037 14.1 0.8 2.6 8.1 0.0 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) SSB PF00436.20 CAM72510.1 - 0.063 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Single-strand binding protein family DUF629 PF04780.7 CAM72510.1 - 0.079 11.4 0.3 6.9 5.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_jaz PF12171.3 CAM72510.1 - 0.14 12.3 4.8 6.6 7.0 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Flag1_repress PF03614.8 CAM72510.1 - 0.14 11.6 0.0 0.75 9.3 0.0 1.9 2 0 0 2 2 2 0 Repressor of phase-1 flagellin zf-Di19 PF05605.7 CAM72510.1 - 0.27 11.4 2.0 11 6.1 0.1 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 CAM72510.1 - 0.64 10.4 10.1 4.3 7.8 0.1 3.6 4 0 0 4 4 4 0 Zinc-finger double domain Thioredoxin PF00085.15 CAM72512.1 - 5.3e-64 212.4 0.5 6.3e-32 109.3 0.0 3.8 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 CAM72512.1 - 1.5e-32 112.8 0.1 1.3e-15 57.7 0.0 3.6 2 2 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 CAM72512.1 - 1.4e-17 63.9 1.9 5.7e-08 32.9 0.1 4.1 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CAM72512.1 - 1.9e-13 50.2 0.1 8.4e-07 28.9 0.0 2.9 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 CAM72512.1 - 1.1e-11 44.7 1.0 0.0051 16.9 0.0 5.0 4 2 2 6 6 6 3 Thioredoxin-like AhpC-TSA PF00578.16 CAM72512.1 - 4.5e-08 32.8 1.0 0.019 14.6 0.0 3.3 2 1 1 3 3 3 2 AhpC/TSA family Thioredoxin_9 PF14595.1 CAM72512.1 - 1.9e-06 27.4 0.0 0.0072 15.8 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_3 PF13192.1 CAM72512.1 - 2.5e-05 24.0 0.0 0.12 12.1 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin domain Redoxin PF08534.5 CAM72512.1 - 6.8e-05 22.4 0.7 0.036 13.6 0.0 3.0 3 0 0 3 3 3 2 Redoxin TraF PF13728.1 CAM72512.1 - 0.0021 17.5 0.0 0.48 9.8 0.0 3.4 3 1 1 4 4 4 1 F plasmid transfer operon protein Thioredoxin_4 PF13462.1 CAM72512.1 - 0.0033 17.4 1.4 5.1 7.0 0.0 4.1 4 1 1 5 5 5 1 Thioredoxin Calsequestrin PF01216.12 CAM72512.1 - 0.0071 15.1 0.3 0.026 13.3 0.2 1.8 2 0 0 2 2 2 1 Calsequestrin HyaE PF07449.6 CAM72512.1 - 0.053 13.4 0.0 0.35 10.7 0.0 2.4 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Methyltransf_23 PF13489.1 CAM72515.1 - 0.015 15.0 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF4080 PF13311.1 CAM72515.1 - 0.15 12.0 1.0 2.9 7.8 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF4080) eIF-3c_N PF05470.7 CAM72516.1 - 5.1e-21 74.4 1.0 2.2e-16 59.0 0.0 2.4 1 1 0 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus RRM_1 PF00076.17 CAM72517.1 - 0.00044 19.8 0.0 0.0011 18.5 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM72517.1 - 0.0032 17.3 0.1 0.017 15.1 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Arg_repressor_C PF02863.13 CAM72517.1 - 0.033 13.6 0.0 0.088 12.2 0.0 1.7 2 0 0 2 2 2 0 Arginine repressor, C-terminal domain Limkain-b1 PF11608.3 CAM72517.1 - 0.059 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 RRM_5 PF13893.1 CAM72517.1 - 0.11 12.3 0.0 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MOZ_SAS PF01853.13 CAM72518.1 - 1.3e-46 158.1 0.0 1.8e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_1 PF00583.19 CAM72518.1 - 0.0075 16.2 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CAM72518.1 - 0.0091 16.1 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CAM72518.1 - 0.018 14.8 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein zf-met PF12874.2 CAM72518.1 - 0.1 12.8 3.0 0.22 11.7 2.1 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 CAM72518.1 - 0.68 10.3 5.2 1.5 9.3 3.6 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CAM72518.1 - 3.7 8.0 8.4 1.9 8.9 3.7 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger PSP1 PF04468.7 CAM72520.1 - 3.3e-30 103.9 0.1 5.6e-30 103.1 0.1 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region DnaJ PF00226.26 CAM72522.2 - 2.9e-07 30.1 0.0 1.4e-06 27.9 0.0 2.1 2 1 0 2 2 2 1 DnaJ domain IF-2B PF01008.12 CAM72523.1 - 6.3e-72 241.9 0.3 7.4e-72 241.7 0.2 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family UPF0029 PF01205.14 CAM72524.1 - 9e-27 92.9 0.0 1.9e-26 91.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 2OG-FeII_Oxy_2 PF13532.1 CAM72525.1 - 2.7e-08 33.8 0.0 1.4e-07 31.5 0.0 2.2 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 CAM72525.1 - 8e-06 26.0 0.1 1.7e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 CAM72525.1 - 0.094 13.2 0.1 0.24 11.9 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily START PF01852.14 CAM72526.1 - 3.7e-05 23.1 0.0 0.82 8.9 0.0 3.2 3 0 0 3 3 3 3 START domain EF-hand_8 PF13833.1 CAM72527.1 - 0.049 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair FYVE PF01363.16 CAM72528.1 - 2.4e-09 36.9 8.4 4.8e-09 35.9 5.8 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 CAM72528.1 - 0.033 14.0 8.3 0.082 12.8 5.7 1.6 1 1 0 1 1 1 0 FYVE-type zinc finger PAT1 PF09770.4 CAM72528.1 - 0.067 11.4 4.9 0.088 11.0 3.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-B_box PF00643.19 CAM72528.1 - 0.28 11.0 9.7 1.2 9.0 3.4 2.6 2 0 0 2 2 2 0 B-box zinc finger C1_1 PF00130.17 CAM72528.1 - 2.3 7.9 11.8 0.33 10.7 4.1 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) His_Phos_2 PF00328.17 CAM72531.1 - 1.2e-17 64.2 0.0 7.6e-13 48.4 0.0 2.2 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) RRM_1 PF00076.17 CAM72532.1 - 0.14 11.7 0.0 0.36 10.4 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Totivirus_coat PF05518.6 CAM72532.1 - 0.89 7.3 8.6 1.1 7.0 5.9 1.0 1 0 0 1 1 1 0 Totivirus coat protein WD40 PF00400.27 CAM72534.1 - 2.9e-24 84.0 18.1 1.8e-06 27.6 0.4 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat Nic96 PF04097.9 CAM72535.1 - 3.1e-98 329.5 0.1 3.9e-98 329.1 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 SNAPc_SNAP43 PF09808.4 CAM72536.1 - 0.0071 16.0 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 DEAD PF00270.24 CAM72537.1 - 3e-26 91.9 0.0 1.1e-25 90.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM72537.1 - 1.1e-17 63.6 0.0 2.7e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 CAM72537.1 - 0.00021 21.2 0.0 0.0052 16.7 0.0 2.2 2 0 0 2 2 2 1 Helicase C-terminal domain K_channel_TID PF07941.6 CAM72537.1 - 0.015 15.4 0.2 0.034 14.3 0.1 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain NAD_binding_3 PF03447.11 CAM72537.1 - 0.042 14.2 0.1 0.11 12.9 0.1 1.7 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain FA_hydroxylase PF04116.8 CAM72538.1 - 2.1e-13 50.6 14.4 2.1e-13 50.6 10.0 3.3 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily HEAT_2 PF13646.1 CAM72540.1 - 0.0093 16.2 4.5 1 9.6 0.0 3.8 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.17 CAM72540.1 - 0.015 15.3 7.8 0.75 10.0 0.0 4.6 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.1 CAM72540.1 - 0.64 10.5 10.1 8.9 6.9 0.1 4.9 4 0 0 4 4 4 0 HEAT-like repeat His_Phos_2 PF00328.17 CAM72541.1 - 9.9e-24 84.2 0.1 5.8e-23 81.7 0.1 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) GDPD PF03009.12 CAM72542.1 - 1.1e-36 126.6 0.0 1.8e-36 125.9 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family His_Phos_2 PF00328.17 CAM72543.1 - 2.4e-20 73.1 0.1 2.3e-19 69.9 0.0 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RCC1 PF00415.13 CAM72544.1 - 4.5e-26 90.8 9.1 1.1e-06 28.7 0.1 6.1 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CAM72544.1 - 1.4e-20 72.3 18.4 1.8e-08 33.7 0.2 4.4 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat DUF4213 PF13938.1 CAM72544.1 - 0.034 14.2 0.1 9.4 6.4 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4213) Mur_ligase_M PF08245.7 CAM72545.1 - 2.9e-11 43.7 0.1 9.7e-11 42.0 0.1 1.8 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 CAM72545.1 - 0.074 13.1 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Mito_fiss_reg PF05308.6 CAM72545.1 - 0.17 11.2 0.7 0.3 10.4 0.5 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Androgen_recep PF02166.11 CAM72545.1 - 1.8 7.3 4.3 40 2.9 0.0 2.2 2 0 0 2 2 2 0 Androgen receptor CAP_N PF01213.14 CAM72545.1 - 4.1 6.6 4.2 6.6 5.9 2.9 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal VRR_NUC PF08774.6 CAM72546.1 - 4.1e-18 65.2 0.0 8.6e-18 64.2 0.0 1.6 1 0 0 1 1 1 1 VRR-NUC domain SPOUT_MTase_2 PF14419.1 CAM72546.1 - 0.36 10.0 0.0 0.65 9.1 0.0 1.3 1 0 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP Pkinase PF00069.20 CAM72547.1 - 2.5e-26 92.3 0.0 9.7e-10 38.0 0.0 3.6 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 CAM72547.1 - 2.9e-11 42.9 0.0 1.2e-09 37.6 0.0 2.8 3 0 0 3 3 3 1 Protein tyrosine kinase PCI PF01399.22 CAM72548.1 - 0.0047 17.2 0.0 0.52 10.6 0.0 2.9 3 0 0 3 3 3 2 PCI domain Methyltransf_11 PF08241.7 CAM72549.1 - 1.1e-10 41.8 0.1 1e-07 32.3 0.0 3.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAM72549.1 - 3.8e-08 33.5 0.0 1.9e-07 31.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAM72549.1 - 5.6e-08 32.6 0.0 8.7e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAM72549.1 - 5.7e-06 26.8 1.4 0.0023 18.4 0.2 2.5 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 CAM72549.1 - 0.00017 21.9 0.0 0.0018 18.7 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CAM72549.1 - 0.00019 21.4 0.1 0.00046 20.1 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAM72549.1 - 0.0051 16.4 0.0 13 5.4 0.0 3.0 3 0 0 3 3 3 2 Methyltransferase domain 2-oxoacid_dh PF00198.18 CAM72550.1 - 9e-77 257.4 0.0 1.2e-76 256.9 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.12 CAM72550.1 - 4.4e-13 48.6 1.9 4.6e-12 45.3 0.3 2.9 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl PF00364.17 CAM72550.1 - 6.5e-11 41.7 0.0 2.1e-10 40.1 0.0 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme DUF3597 PF12200.3 CAM72550.1 - 4.2 7.7 10.6 14 6.0 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) Metallophos_2 PF12850.2 CAM72551.1 - 1.4e-06 28.2 0.0 2.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pentapeptide_4 PF13599.1 CAM72553.1 - 5.7e-10 38.8 9.0 1e-08 34.8 5.9 2.7 2 1 1 3 3 3 2 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 CAM72553.1 - 7.2e-09 34.6 14.0 0.0024 17.0 1.1 4.5 3 1 2 5 5 5 4 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.1 CAM72553.1 - 9.2e-09 35.0 9.6 4.7e-06 26.3 0.6 4.2 2 1 2 4 4 4 3 Pentapeptide repeats (9 copies) Prominin PF05478.6 CAM72554.1 - 0.21 9.0 0.6 0.29 8.6 0.4 1.1 1 0 0 1 1 1 0 Prominin Acyl-CoA_dh_C PF12806.2 CAM72554.1 - 0.61 9.9 8.7 1.2 9.0 5.4 1.9 1 1 1 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like Peptidase_M41 PF01434.13 CAM72556.1 - 7e-64 215.2 0.4 9.8e-64 214.7 0.3 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CAM72556.1 - 1.9e-41 141.3 0.0 3.6e-41 140.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 CAM72556.1 - 4.3e-06 26.2 0.8 0.00077 18.9 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 CAM72556.1 - 1.3e-05 24.9 0.0 4.3e-05 23.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CAM72556.1 - 2.9e-05 24.2 0.2 0.00072 19.7 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CAM72556.1 - 4.8e-05 23.2 0.0 0.00014 21.8 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 CAM72556.1 - 5e-05 23.3 0.1 0.0057 16.6 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 CAM72556.1 - 0.00012 22.8 0.0 0.00035 21.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CAM72556.1 - 0.00014 20.9 0.0 0.0003 19.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 CAM72556.1 - 0.00075 19.2 0.1 0.011 15.3 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 CAM72556.1 - 0.00079 19.1 0.1 0.0026 17.4 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 CAM72556.1 - 0.00087 18.7 0.0 0.0023 17.3 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 CAM72556.1 - 0.00092 18.0 0.0 0.0023 16.7 0.0 1.6 2 0 0 2 2 2 1 TIP49 C-terminus AAA_28 PF13521.1 CAM72556.1 - 0.0012 18.8 0.0 0.006 16.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CAM72556.1 - 0.0026 18.0 0.0 0.0071 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CAM72556.1 - 0.0045 16.1 0.0 0.0093 15.0 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 CAM72556.1 - 0.0047 16.1 0.2 0.01 15.0 0.2 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.10 CAM72556.1 - 0.01 14.5 0.0 0.015 13.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_33 PF13671.1 CAM72556.1 - 0.015 15.2 0.0 0.032 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CAM72556.1 - 0.017 15.2 0.0 0.098 12.8 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_2 PF07724.9 CAM72556.1 - 0.017 15.0 0.0 0.065 13.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Reprolysin_4 PF13583.1 CAM72556.1 - 0.02 14.4 0.0 0.041 13.4 0.0 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like KaiC PF06745.8 CAM72556.1 - 0.054 12.5 0.1 0.67 9.0 0.0 2.6 3 0 0 3 3 3 0 KaiC ABC_tran PF00005.22 CAM72556.1 - 0.062 13.6 0.6 0.27 11.5 0.2 2.2 2 0 0 2 2 2 0 ABC transporter Arch_ATPase PF01637.13 CAM72556.1 - 0.077 12.6 0.0 0.23 11.1 0.0 1.9 1 1 1 2 2 2 0 Archaeal ATPase Parvo_NS1 PF01057.12 CAM72556.1 - 0.2 10.4 0.0 0.37 9.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 HEAT_EZ PF13513.1 CAM72557.1 - 0.0001 22.6 7.9 0.0064 16.9 0.0 5.8 7 0 0 7 7 7 1 HEAT-like repeat HEAT PF02985.17 CAM72557.1 - 0.00045 20.0 2.5 6.3 7.1 0.0 5.9 6 0 0 6 6 6 1 HEAT repeat B56 PF01603.15 CAM72557.1 - 0.005 15.5 0.0 0.017 13.7 0.0 1.9 2 0 0 2 2 2 1 Protein phosphatase 2A regulatory B subunit (B56 family) RIX1 PF08167.7 CAM72557.1 - 0.0094 15.6 4.7 0.041 13.5 0.6 2.6 1 1 0 2 2 2 1 rRNA processing/ribosome biogenesis Alph_Pro_TM PF09608.5 CAM72557.1 - 0.025 14.1 0.0 0.082 12.4 0.0 1.8 2 0 0 2 2 2 0 Putative transmembrane protein (Alph_Pro_TM) IBN_N PF03810.14 CAM72557.1 - 0.052 13.4 2.9 0.84 9.5 0.1 3.9 3 1 0 3 3 3 0 Importin-beta N-terminal domain Tyr_Deacylase PF02580.11 CAM72558.1 - 1.8e-41 141.4 0.0 2e-41 141.3 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Acetyltransf_1 PF00583.19 CAM72560.1 - 5.7e-15 55.1 0.1 8.6e-15 54.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CAM72560.1 - 5.6e-05 23.2 0.2 9.5e-05 22.4 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CAM72560.1 - 0.00021 21.3 0.0 0.00028 20.9 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CAM72560.1 - 0.0016 18.2 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 CAM72560.1 - 0.002 17.8 0.0 0.0067 16.1 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.1 CAM72560.1 - 0.029 14.2 0.3 0.046 13.5 0.2 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 CAM72560.1 - 0.046 13.6 0.3 0.11 12.3 0.2 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Mec-17 PF05301.6 CAM72560.1 - 0.053 13.4 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 Touch receptor neuron protein Mec-17 MFS_1 PF07690.11 CAM72561.1 - 1e-13 50.7 42.7 6.2e-13 48.1 18.7 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 CAM72561.1 - 3.2e-13 49.4 12.3 3.2e-13 49.4 8.5 2.0 2 1 0 2 2 2 1 Nodulin-like DUF2399 PF09664.5 CAM72563.1 - 0.00051 19.9 0.0 0.00091 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2399) TP6A_N PF04406.9 CAM72563.1 - 0.006 16.2 0.0 0.087 12.5 0.0 2.3 2 0 0 2 2 2 1 Type IIB DNA topoisomerase NDK PF00334.14 CAM72564.1 - 0.00065 19.5 0.0 0.063 13.0 0.0 3.4 4 0 0 4 4 4 1 Nucleoside diphosphate kinase EF-hand_7 PF13499.1 CAM72564.1 - 0.38 10.9 0.0 1.3 9.2 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair RGS PF00615.14 CAM72567.1 - 0.021 14.9 0.5 0.19 11.8 0.0 2.2 2 0 0 2 2 2 0 Regulator of G protein signaling domain OB_NTP_bind PF07717.11 CAM72568.1 - 4.7e-24 84.4 0.0 5.8e-23 80.8 0.0 2.4 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CAM72568.1 - 6.4e-20 71.0 0.0 2.4e-19 69.2 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CAM72568.1 - 1.5e-12 47.2 0.0 6.7e-12 45.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAM72568.1 - 3.4e-08 33.1 0.2 2e-07 30.6 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CAM72568.1 - 8.6e-06 25.9 0.8 3.8e-05 23.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CAM72568.1 - 0.007 16.2 0.1 0.48 10.2 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CAM72568.1 - 0.012 15.3 0.1 0.042 13.6 0.1 1.9 1 0 0 1 1 1 0 Part of AAA domain Zeta_toxin PF06414.7 CAM72568.1 - 0.014 14.4 1.3 0.53 9.3 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin AAA_29 PF13555.1 CAM72568.1 - 0.053 13.0 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zot PF05707.7 CAM72568.1 - 0.057 12.8 0.0 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) ABC_tran PF00005.22 CAM72568.1 - 0.058 13.6 0.1 0.66 10.2 0.1 2.6 1 1 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 CAM72568.1 - 0.14 12.4 0.0 0.14 12.4 0.0 2.3 2 1 0 2 2 1 0 AAA domain Phytochelatin PF05023.9 CAM72569.1 - 0.0029 16.6 0.0 4.6 6.1 0.0 4.3 5 0 0 5 5 5 2 Phytochelatin synthase RasGAP_C PF03836.10 CAM72570.1 - 0.0045 16.6 0.6 0.0051 16.5 0.4 1.1 1 0 0 1 1 1 1 RasGAP C-terminus GvpG PF05120.7 CAM72570.1 - 0.018 14.8 2.5 0.026 14.3 1.7 1.3 1 0 0 1 1 1 0 Gas vesicle protein G Spc24 PF08286.6 CAM72570.1 - 0.021 14.5 2.9 0.024 14.3 2.0 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF2968 PF11180.3 CAM72570.1 - 0.026 13.8 6.1 0.028 13.8 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF972 PF06156.8 CAM72570.1 - 0.031 14.6 1.9 0.047 14.0 1.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Borrelia_lipo_1 PF05714.6 CAM72570.1 - 0.032 13.3 0.2 0.037 13.1 0.1 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein Baculo_PEP_C PF04513.7 CAM72570.1 - 0.036 13.8 0.8 0.041 13.7 0.6 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 CAM72570.1 - 0.038 12.6 2.2 0.039 12.6 1.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Cast PF10174.4 CAM72570.1 - 0.043 11.8 4.3 0.045 11.8 3.0 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone IncA PF04156.9 CAM72570.1 - 0.051 13.1 6.5 0.089 12.3 4.5 1.3 1 1 0 1 1 1 0 IncA protein APG6 PF04111.7 CAM72570.1 - 0.062 12.3 3.8 0.071 12.1 2.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3294 PF07957.6 CAM72570.1 - 0.066 12.7 0.8 0.066 12.7 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3294) FUSC PF04632.7 CAM72570.1 - 0.075 11.4 4.4 0.079 11.3 3.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Bacillus_HBL PF05791.6 CAM72570.1 - 0.086 12.2 1.6 0.1 11.9 1.1 1.1 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) TBPIP PF07106.8 CAM72570.1 - 0.089 12.3 0.7 0.11 12.0 0.5 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF948 PF06103.6 CAM72570.1 - 0.092 12.6 0.6 0.15 11.9 0.3 1.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF342 PF03961.8 CAM72570.1 - 0.094 11.1 0.8 0.098 11.0 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Borrelia_P83 PF05262.6 CAM72570.1 - 0.1 10.8 3.2 0.1 10.8 2.2 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein HAUS5 PF14817.1 CAM72570.1 - 0.1 11.0 3.0 0.11 11.0 2.1 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Atg14 PF10186.4 CAM72570.1 - 0.12 11.2 2.0 0.14 11.0 1.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CENP-Q PF13094.1 CAM72570.1 - 0.13 12.2 5.3 0.16 11.9 3.7 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit OmpH PF03938.9 CAM72570.1 - 0.14 12.0 6.2 0.16 11.8 4.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ADIP PF11559.3 CAM72570.1 - 0.15 11.9 5.2 0.17 11.7 3.6 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.14 CAM72570.1 - 0.2 9.4 0.5 0.2 9.4 0.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2894 PF11445.3 CAM72570.1 - 0.25 11.5 3.0 0.28 11.4 2.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) HemX PF04375.9 CAM72570.1 - 0.47 8.9 6.9 0.53 8.8 4.8 1.0 1 0 0 1 1 1 0 HemX NPV_P10 PF05531.7 CAM72570.1 - 0.5 10.6 2.3 1.8 8.8 1.6 1.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF904 PF06005.7 CAM72570.1 - 0.52 10.6 5.7 4.9 7.5 3.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DivIC PF04977.10 CAM72570.1 - 0.56 9.7 9.4 2.2 7.8 0.4 2.2 1 1 1 2 2 2 0 Septum formation initiator Wbp11 PF09429.5 CAM72570.1 - 0.67 9.9 4.2 0.49 10.4 1.1 1.8 1 1 1 2 2 2 0 WW domain binding protein 11 bZIP_2 PF07716.10 CAM72570.1 - 0.68 9.8 7.1 3.8 7.4 1.1 2.1 2 0 0 2 2 2 0 Basic region leucine zipper DUF4407 PF14362.1 CAM72570.1 - 0.68 8.8 3.9 0.75 8.6 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SseC PF04888.7 CAM72570.1 - 0.9 8.8 4.3 0.97 8.7 3.0 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family T2SM PF04612.7 CAM72570.1 - 1.7 8.4 6.4 0.49 10.1 1.9 1.7 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M Chlorosome_CsmC PF11098.3 CAM72571.1 - 0.045 13.4 0.2 0.07 12.8 0.1 1.3 1 0 0 1 1 1 0 Chlorosome envelope protein C zf-RanBP PF00641.13 CAM72572.2 - 2e-19 68.3 80.8 5.5e-09 34.9 1.9 9.5 9 0 0 9 9 9 7 Zn-finger in Ran binding protein and others DZR PF12773.2 CAM72572.2 - 4.9e-07 29.4 67.1 0.0035 17.1 4.5 7.2 3 2 5 8 8 8 8 Double zinc ribbon PolC_DP2 PF03833.8 CAM72572.2 - 0.00072 17.3 2.9 0.00072 17.3 2.0 3.5 3 1 1 4 4 4 1 DNA polymerase II large subunit DP2 DZR PF12773.2 CAM72573.1 - 0.015 15.1 123.6 0.025 14.4 5.8 10.4 4 3 2 7 7 7 0 Double zinc ribbon ARL2_Bind_BART PF11527.3 CAM72574.1 - 1.2e-36 125.1 1.6 1.2e-36 125.1 1.1 1.8 2 0 0 2 2 2 1 The ARF-like 2 binding protein BART UIM PF02809.15 CAM72574.1 - 0.0041 16.5 0.1 0.0041 16.5 0.1 4.1 5 0 0 5 5 5 1 Ubiquitin interaction motif UBA PF00627.26 CAM72574.1 - 0.032 14.0 0.1 0.1 12.4 0.0 1.9 1 0 0 1 1 1 0 UBA/TS-N domain PAT1 PF09770.4 CAM72574.1 - 0.13 10.5 25.8 0.17 10.0 17.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 IL15 PF02372.10 CAM72574.1 - 0.2 11.4 3.2 2.6 7.8 0.2 2.6 2 0 0 2 2 2 0 Interleukin 15 DUF755 PF05501.6 CAM72575.1 - 0.028 14.4 5.6 0.09 12.8 3.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Trypsin_2 PF13365.1 CAM72576.1 - 7.8e-06 25.8 0.0 1.4e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain AAA PF00004.24 CAM72577.1 - 7.5e-61 204.1 0.0 2.8e-46 156.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 CAM72577.1 - 3.9e-22 78.0 0.2 1.6e-21 76.0 0.1 2.2 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.12 CAM72577.1 - 5.8e-10 38.6 0.0 1.3e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_17 PF13207.1 CAM72577.1 - 1.7e-06 28.8 0.0 0.0006 20.6 0.0 3.2 2 2 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CAM72577.1 - 1.9e-05 23.8 0.0 5.4e-05 22.3 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CAM72577.1 - 2.4e-05 24.4 0.1 0.00056 19.9 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain Vps4_C PF09336.5 CAM72577.1 - 3.1e-05 23.7 0.0 0.00038 20.2 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.9 CAM72577.1 - 0.00073 19.2 0.1 0.019 14.7 0.0 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 CAM72577.1 - 0.00077 18.6 0.0 0.0016 17.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 CAM72577.1 - 0.0012 18.9 0.0 0.0097 16.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CAM72577.1 - 0.0014 18.7 0.0 0.0034 17.5 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.1 CAM72577.1 - 0.0014 18.5 0.0 0.0046 16.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 CAM72577.1 - 0.0023 17.8 0.0 0.0091 15.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 CAM72577.1 - 0.0031 16.9 0.1 0.015 14.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CAM72577.1 - 0.0047 16.3 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Viral_helicase1 PF01443.13 CAM72577.1 - 0.0066 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Molydop_binding PF01568.16 CAM72577.1 - 0.007 16.1 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain AAA_14 PF13173.1 CAM72577.1 - 0.0074 16.1 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CAM72577.1 - 0.0098 15.0 0.0 0.024 13.8 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 CAM72577.1 - 0.01 16.1 0.0 0.037 14.3 0.0 1.9 1 0 0 1 1 1 0 ABC transporter Bac_DnaA PF00308.13 CAM72577.1 - 0.013 15.1 0.0 2.3 7.7 0.0 2.5 2 0 0 2 2 2 0 Bacterial dnaA protein TIP49 PF06068.8 CAM72577.1 - 0.023 13.4 0.0 0.045 12.4 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus Parvo_NS1 PF01057.12 CAM72577.1 - 0.024 13.5 0.0 0.04 12.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.7 CAM72577.1 - 0.024 14.2 0.0 0.13 11.8 0.0 2.1 1 1 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 CAM72577.1 - 0.03 14.2 0.0 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 CAM72577.1 - 0.032 14.5 0.0 0.09 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain TEX19 PF15553.1 CAM72577.1 - 0.049 13.5 0.1 0.084 12.7 0.1 1.3 1 0 0 1 1 1 0 Testis-expressed protein 19 AAA_19 PF13245.1 CAM72577.1 - 0.057 13.1 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain eIF-1a PF01176.14 CAM72577.1 - 0.075 12.4 1.1 2.1 7.8 0.0 2.9 3 0 0 3 3 3 0 Translation initiation factor 1A / IF-1 AAA_24 PF13479.1 CAM72577.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ADK PF00406.17 CAM72578.1 - 8e-42 142.6 0.0 1.5e-41 141.7 0.0 1.4 1 1 1 2 2 2 1 Adenylate kinase AAA_17 PF13207.1 CAM72578.1 - 5e-11 43.4 0.0 2.2e-10 41.4 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 CAM72578.1 - 7.1e-10 39.2 0.2 4.9e-09 36.5 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 CAM72578.1 - 1.7e-05 24.7 0.7 0.00015 21.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain ADK_lid PF05191.9 CAM72578.1 - 3.7e-05 23.2 0.0 8e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid Zeta_toxin PF06414.7 CAM72578.1 - 0.0025 16.9 0.1 0.01 14.9 0.0 2.0 3 0 0 3 3 3 1 Zeta toxin AAA PF00004.24 CAM72578.1 - 0.0027 17.9 0.0 0.0093 16.1 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CAM72578.1 - 0.034 13.1 0.2 0.098 11.6 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus Thymidylate_kin PF02223.12 CAM72578.1 - 0.051 12.9 0.5 3.3 7.0 0.0 2.9 2 1 1 3 3 3 0 Thymidylate kinase KTI12 PF08433.5 CAM72578.1 - 0.086 12.0 0.1 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 zf-PARP PF00645.13 CAM72579.1 - 1e-22 80.1 0.6 2.2e-22 79.0 0.4 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-CCHH PF10283.4 CAM72579.1 - 1.4e-11 44.0 5.5 2.2e-11 43.3 3.8 1.3 1 0 0 1 1 1 1 Zinc-finger (CX5CX6HX5H) motif NARP1 PF12569.3 CAM72580.1 - 6.2e-87 292.5 12.8 3.6e-83 280.0 6.8 2.4 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 CAM72580.1 - 1.6e-19 69.3 11.3 2.6e-05 23.7 0.0 5.9 6 0 0 6 6 6 3 TPR repeat TPR_2 PF07719.12 CAM72580.1 - 2.2e-13 48.9 13.8 0.00026 20.6 0.0 7.4 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 CAM72580.1 - 1.8e-11 43.5 17.6 0.13 13.0 0.0 8.3 7 1 2 9 9 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 CAM72580.1 - 6.1e-11 41.4 7.8 7.3e-05 22.2 0.0 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 CAM72580.1 - 9.6e-09 35.4 8.3 0.024 14.9 0.0 5.3 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 CAM72580.1 - 2.9e-08 34.1 21.2 0.0014 19.2 0.0 6.8 6 2 1 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 CAM72580.1 - 3.5e-08 33.0 3.2 0.92 9.8 0.0 6.2 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 CAM72580.1 - 8.9e-08 31.8 4.2 0.00059 19.6 0.0 4.6 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 CAM72580.1 - 6.1e-07 29.2 11.3 0.073 13.0 1.3 5.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 CAM72580.1 - 1e-06 28.0 0.3 0.32 10.8 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 CAM72580.1 - 0.0039 16.8 11.5 1.4 8.8 0.0 6.7 8 0 0 8 8 7 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CAM72580.1 - 0.0041 16.9 0.9 18 5.2 0.0 4.3 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat DUF1771 PF08590.5 CAM72580.1 - 9.7 6.2 11.5 0.95 9.5 1.9 3.3 2 1 1 3 3 2 0 Domain of unknown function (DUF1771) DnaJ PF00226.26 CAM72581.1 - 2.5e-09 36.7 0.0 4.9e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain LpxC PF03331.8 CAM72581.1 - 0.038 12.9 0.1 1.5 7.7 0.0 2.1 2 0 0 2 2 2 0 UDP-3-O-acyl N-acetylglycosamine deacetylase DUF3278 PF11683.3 CAM72581.1 - 0.16 11.9 1.1 0.27 11.2 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) DUF3491 PF11996.3 CAM72581.1 - 0.17 9.3 0.0 0.23 8.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3491) DUF1151 PF06625.6 CAM72582.1 - 0.47 10.1 4.2 1.1 8.9 2.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) CAF-1_p150 PF11600.3 CAM72583.1 - 0.0046 16.3 8.9 0.0062 15.9 6.2 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4192 PF13830.1 CAM72583.1 - 0.16 11.5 7.7 0.23 11.0 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) APG6 PF04111.7 CAM72583.1 - 0.54 9.2 7.7 0.81 8.6 5.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1682 PF07946.9 CAM72583.1 - 8.4 5.1 9.2 1.2e+02 1.3 7.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) SIP1 PF04938.7 CAM72584.1 - 0.00067 19.0 0.0 0.0022 17.4 0.0 1.9 2 0 0 2 2 2 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) DUF3094 PF11293.3 CAM72585.1 - 0.021 14.2 3.4 0.91 9.0 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3094) ESX-1_EspG PF14011.1 CAM72585.1 - 0.05 12.8 2.0 0.071 12.3 0.5 1.7 2 0 0 2 2 2 0 EspG family Glycolytic PF00274.14 CAM72586.1 - 3.5e-143 476.2 0.0 3.9e-143 476.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Ribosomal_S4 PF00163.14 CAM72587.1 - 7.7e-29 99.9 0.4 1.5e-28 98.9 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CAM72587.1 - 6.2e-14 51.1 0.4 1.3e-13 50.1 0.3 1.6 1 0 0 1 1 1 1 S4 domain PP2C PF00481.16 CAM72589.1 - 4e-09 36.2 0.0 6.5e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C ATG16 PF08614.6 CAM72590.1 - 0.0018 18.1 0.4 0.0037 17.1 0.3 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Glyco_transf_22 PF03901.12 CAM72592.1 - 1.6e-66 225.0 25.8 1.9e-66 224.8 17.9 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF2651 PF10852.3 CAM72592.1 - 2.8 8.3 8.9 1.7 9.0 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2651) Abhydrolase_9 PF10081.4 CAM72593.1 - 0.025 13.2 0.1 0.031 12.9 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta-hydrolase family COQ7 PF03232.8 CAM72593.1 - 0.052 13.0 0.2 0.073 12.5 0.1 1.2 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 CorA PF01544.13 CAM72595.1 - 0.00032 19.8 0.1 0.00099 18.2 0.0 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Memo PF01875.12 CAM72596.1 - 1.4e-61 207.8 0.0 1.9e-61 207.3 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein 3HCDH_N PF02737.13 CAM72598.1 - 1.6e-56 190.7 1.6 2e-56 190.4 1.1 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 CAM72598.1 - 3.1e-34 117.2 0.0 1.2e-33 115.4 0.0 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 CAM72598.1 - 0.0061 16.4 0.7 0.019 14.7 0.5 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.22 CAM72598.1 - 0.016 15.5 0.0 0.041 14.2 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 CAM72598.1 - 0.049 14.0 0.5 0.11 12.9 0.3 1.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 CAM72598.1 - 0.064 12.9 1.7 0.18 11.5 1.2 1.7 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.16 CAM72598.1 - 0.077 12.5 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.19 CAM72598.1 - 0.14 10.9 0.8 0.23 10.2 0.5 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase HORMA PF02301.13 CAM72601.1 - 7.7e-46 156.1 0.0 1e-45 155.8 0.0 1.2 1 0 0 1 1 1 1 HORMA domain Ribosomal_L24e PF01246.15 CAM72602.2 - 8e-15 54.4 0.5 8e-15 54.4 0.3 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e DUF4189 PF13827.1 CAM72603.1 - 0.022 14.9 1.1 0.046 13.9 0.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4189) Ribosomal_L24e PF01246.15 CAM72605.1 - 8e-15 54.4 0.5 8e-15 54.4 0.3 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e DDT PF02791.12 CAM72606.1 - 0.00035 20.2 0.8 0.00075 19.2 0.1 2.0 2 0 0 2 2 2 1 DDT domain WHIM2 PF15613.1 CAM72606.1 - 0.0011 18.7 0.1 0.0033 17.3 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 Ribonuclease_3 PF00636.21 CAM72607.1 - 0.0058 17.0 0.0 0.025 15.0 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease III domain CLAMP PF14769.1 CAM72608.1 - 6.6e-30 103.2 1.0 1.3e-29 102.3 0.7 1.5 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 Ribosomal_L28e PF01778.12 CAM72608.1 - 0.14 12.5 0.2 0.27 11.6 0.1 1.4 1 0 0 1 1 1 0 Ribosomal L28e protein family LOH1CR12 PF10158.4 CAM72611.1 - 0.022 14.5 1.6 0.051 13.3 1.1 1.6 1 0 0 1 1 1 0 Tumour suppressor protein WD40 PF00400.27 CAM72612.1 - 3.2e-14 52.1 21.0 1.3e-10 40.7 0.3 7.7 9 0 0 9 9 9 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 CAM72612.1 - 3.1e-05 22.9 0.0 0.0028 16.5 0.0 3.7 4 0 0 4 4 4 1 Coatomer WD associated region Clathrin PF00637.15 CAM72612.1 - 0.00015 21.3 1.8 0.02 14.5 0.0 3.5 2 1 2 4 4 4 2 Region in Clathrin and VPS TPR_7 PF13176.1 CAM72612.1 - 0.0034 17.0 2.4 2.2 8.3 0.0 4.6 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 CAM72612.1 - 0.048 14.3 7.3 14 6.6 0.3 5.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 CAM72612.1 - 0.85 9.6 10.6 13 6.0 0.2 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 CAM72612.1 - 2.3 8.1 7.9 82 3.3 0.0 5.2 7 0 0 7 7 7 0 Tetratricopeptide repeat S10_plectin PF03501.10 CAM72613.1 - 2.8e-34 116.8 0.0 3.3e-34 116.5 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain API5 PF05918.6 CAM72613.1 - 4 5.8 15.3 5.9 5.2 10.6 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) S10_plectin PF03501.10 CAM72614.1 - 2.8e-34 116.8 0.0 3.3e-34 116.5 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain API5 PF05918.6 CAM72614.1 - 4 5.8 15.3 5.9 5.2 10.6 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Dynein_heavy PF03028.10 CAM72617.1 - 1.1e-215 717.8 0.0 1.1e-215 717.8 0.0 3.6 4 0 0 4 4 3 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 CAM72617.1 - 2.1e-125 418.4 13.1 2.1e-125 418.4 9.1 3.4 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CAM72617.1 - 2.3e-91 305.4 0.1 1.2e-90 303.0 0.0 2.2 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 CAM72617.1 - 1.3e-70 237.4 0.3 3e-70 236.2 0.2 1.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 CAM72617.1 - 2.2e-54 183.6 0.1 5.3e-54 182.4 0.0 1.7 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 CAM72617.1 - 1.3e-44 152.3 8.5 3.1e-44 151.1 5.9 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 CAM72617.1 - 3.2e-38 131.3 0.0 5.7e-38 130.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 CAM72617.1 - 1.6e-15 57.0 0.0 0.0001 22.0 0.0 7.4 7 2 0 7 7 6 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CAM72617.1 - 3.6e-10 40.0 0.5 5.1e-06 26.6 0.0 4.6 4 0 0 4 4 3 2 AAA domain RNA_helicase PF00910.17 CAM72617.1 - 1.2e-05 25.3 0.0 0.069 13.3 0.0 3.8 3 0 0 3 3 3 1 RNA helicase NACHT PF05729.7 CAM72617.1 - 2.3e-05 24.0 0.1 0.0066 16.1 0.0 3.7 2 0 0 2 2 2 1 NACHT domain AAA PF00004.24 CAM72617.1 - 2.4e-05 24.5 0.0 0.34 11.1 0.0 3.7 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CAM72617.1 - 0.00059 19.7 0.0 1.7 8.5 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 CAM72617.1 - 0.0026 17.2 2.9 0.17 11.3 0.0 4.2 5 0 0 5 5 4 1 AAA-like domain AAA_19 PF13245.1 CAM72617.1 - 0.0075 15.9 1.0 0.65 9.7 0.1 3.6 3 0 0 3 3 3 1 Part of AAA domain AAA_16 PF13191.1 CAM72617.1 - 0.035 14.1 14.0 0.52 10.2 0.0 5.5 5 2 0 5 5 4 0 AAA ATPase domain AAA_17 PF13207.1 CAM72617.1 - 0.037 14.8 0.0 7.4 7.4 0.0 3.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 CAM72617.1 - 0.049 13.9 1.1 4.1 7.7 0.0 4.0 4 0 0 4 4 3 0 AAA domain ATP-synt_ab PF00006.20 CAM72617.1 - 0.15 11.5 0.0 15 4.9 0.0 2.8 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Noelin-1 PF12308.3 CAM72617.1 - 0.18 11.6 7.7 0.85 9.4 0.7 3.5 3 0 0 3 3 2 0 Neurogenesis glycoprotein Gp58 PF07902.6 CAM72617.1 - 0.18 10.0 0.5 0.4 8.8 0.4 1.5 1 0 0 1 1 1 0 gp58-like protein MobB PF03205.9 CAM72617.1 - 0.33 10.6 0.0 8 6.1 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 CAM72617.1 - 2 7.7 8.4 5.2 6.4 0.0 3.9 4 0 0 4 4 3 0 AAA domain MutS_III PF05192.13 CAM72617.1 - 4.8 6.9 18.1 29 4.3 0.1 4.5 2 2 0 2 2 2 0 MutS domain III Ribosomal_S13 PF00416.17 CAM72618.1 - 2.4e-32 111.5 0.2 2.8e-32 111.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DUF4004 PF13171.1 CAM72618.1 - 0.013 15.6 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4004) Ribosomal_S13 PF00416.17 CAM72619.1 - 3.1e-32 111.1 0.2 3.8e-32 110.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DUF4004 PF13171.1 CAM72619.1 - 0.014 15.5 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4004) Ribonuclease_3 PF00636.21 CAM72620.1 - 0.0077 16.6 0.0 0.1 13.0 0.0 2.5 1 1 0 1 1 1 1 Ribonuclease III domain Pkinase PF00069.20 CAM72621.1 - 8.7e-52 175.8 0.0 1.4e-51 175.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM72621.1 - 1e-30 106.6 0.0 1.6e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CAM72621.1 - 0.0025 17.5 0.4 0.0071 16.1 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family ETRAMP PF09716.5 CAM72621.1 - 0.15 12.0 0.0 0.64 10.0 0.0 2.1 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Pkinase PF00069.20 CAM72622.1 - 3.1e-69 233.0 0.0 5.7e-69 232.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM72622.1 - 1.2e-36 126.1 0.0 1.9e-36 125.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM72622.1 - 1.3e-06 27.6 0.0 2.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 CAM72622.1 - 0.0037 16.6 0.9 0.012 14.9 0.1 2.0 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kdo PF06293.9 CAM72622.1 - 0.023 13.7 0.1 0.045 12.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CAM72622.1 - 0.049 13.3 0.1 3.3 7.3 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family eIF-6 PF01912.13 CAM72623.1 - 2.2e-81 271.7 0.8 2.6e-81 271.4 0.2 1.3 2 0 0 2 2 2 1 eIF-6 family NifU PF01106.12 CAM72624.1 - 6.1e-20 70.7 0.1 1.6e-19 69.4 0.1 1.7 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.6 CAM72624.1 - 3.5e-06 26.5 0.0 9.4e-06 25.1 0.0 1.7 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal HA2 PF04408.18 CAM72625.1 - 3.4e-18 65.5 0.0 7.9e-18 64.3 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CAM72625.1 - 3.3e-15 55.7 0.0 1e-14 54.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 CAM72625.1 - 4.2e-11 42.6 0.0 8.9e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 CAM72625.1 - 4.6e-09 35.9 0.0 2.8e-08 33.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase T2SE PF00437.15 CAM72625.1 - 0.00083 18.3 0.0 0.0024 16.8 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 CAM72625.1 - 0.001 19.1 0.4 0.011 15.8 0.3 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CAM72625.1 - 0.0025 17.5 0.2 0.02 14.6 0.0 2.7 3 0 0 3 3 3 1 Part of AAA domain KaiC PF06745.8 CAM72625.1 - 0.015 14.3 0.0 0.031 13.3 0.0 1.5 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 CAM72625.1 - 0.026 14.1 0.1 0.37 10.4 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Sigma54_activ_2 PF14532.1 CAM72625.1 - 0.032 14.2 0.1 0.17 11.9 0.0 2.3 3 0 0 3 3 1 0 Sigma-54 interaction domain AAA_23 PF13476.1 CAM72625.1 - 0.035 14.4 0.0 0.076 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 CAM72625.1 - 0.04 13.4 0.0 0.14 11.5 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.11 CAM72625.1 - 0.043 13.0 0.0 0.094 11.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.17 CAM72625.1 - 0.096 11.5 0.0 0.68 8.7 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_29 PF13555.1 CAM72625.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 CAM72625.1 - 0.11 12.7 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 ABC transporter cobW PF02492.14 CAM72625.1 - 0.12 11.7 0.1 1.9 7.8 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ResIII PF04851.10 CAM72625.1 - 0.15 11.8 0.0 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF972 PF06156.8 CAM72625.1 - 0.19 12.1 0.3 0.55 10.6 0.1 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF972) Pkinase PF00069.20 CAM72626.1 - 6.2e-55 186.1 0.0 8.1e-55 185.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM72626.1 - 5.5e-32 110.8 0.0 7.6e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM72626.1 - 0.011 14.7 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 CAM72626.1 - 0.017 14.8 3.2 0.28 10.8 0.0 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF4613 PF15390.1 CAM72627.1 - 0.0041 15.3 7.1 0.0081 14.4 4.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4613) TMF_DNA_bd PF12329.3 CAM72627.1 - 0.15 11.9 10.7 1.5 8.7 2.0 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CSD PF00313.17 CAM72627.1 - 0.22 11.3 0.0 0.56 10.0 0.0 1.6 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain KaiC PF06745.8 CAM72627.1 - 0.25 10.4 0.3 0.4 9.7 0.2 1.3 1 0 0 1 1 1 0 KaiC DivIC PF04977.10 CAM72627.1 - 0.55 9.7 13.3 0.04 13.4 1.6 2.7 2 1 0 2 2 2 0 Septum formation initiator DUF972 PF06156.8 CAM72627.1 - 1.2 9.5 8.4 1.1 9.6 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) SlyX PF04102.7 CAM72627.1 - 2.2 8.7 18.9 6.6 7.1 2.5 3.0 2 1 1 3 3 3 0 SlyX DUF3373 PF11853.3 CAM72627.1 - 3.7 5.9 10.2 0.25 9.8 2.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3373) Fib_alpha PF08702.5 CAM72627.1 - 5.3 7.1 8.0 1.8 8.6 0.3 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family ABC_tran_2 PF12848.2 CAM72627.1 - 8.3 6.3 13.3 3.9 7.3 3.6 2.5 2 0 0 2 2 2 0 ABC transporter Spc24 PF08286.6 CAM72627.1 - 8.9 6.0 9.1 0.55 9.9 0.9 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 zf-CCCH PF00642.19 CAM72628.1 - 0.0053 16.4 11.9 0.036 13.7 0.3 2.9 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LRV_FeS PF05484.6 CAM72628.1 - 1.2 8.7 7.1 3.8 7.1 0.9 2.6 2 0 0 2 2 2 0 LRV protein FeS4 cluster cNMP_binding PF00027.24 CAM72629.1 - 2.4e-21 75.3 0.0 1.6e-12 47.0 0.0 3.8 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain C2 PF00168.25 CAM72629.1 - 1.2e-07 31.4 0.0 0.00017 21.3 0.0 3.3 3 0 0 3 3 3 2 C2 domain Arf PF00025.16 CAM72630.1 - 5e-30 104.0 0.0 7.1e-30 103.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 CAM72630.1 - 1.8e-09 36.8 0.0 1.2e-08 34.1 0.0 2.1 1 1 1 2 2 2 1 G-protein alpha subunit Ras PF00071.17 CAM72630.1 - 2.6e-08 33.4 0.0 3.9e-08 32.8 0.0 1.4 1 1 0 1 1 1 1 Ras family SRPRB PF09439.5 CAM72630.1 - 9.8e-06 24.9 0.0 2.1e-05 23.8 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Ribosomal_60s PF00428.14 CAM72630.1 - 0.24 11.7 4.6 0.12 12.7 0.5 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Tfb2 PF03849.9 CAM72632.1 - 2.5e-21 75.7 0.0 4.2e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 CAM72632.1 - 1.8e-08 34.2 0.1 8.1e-06 25.6 0.0 2.9 3 0 0 3 3 3 2 Helicase conserved C-terminal domain Peptidase_C2 PF00648.16 CAM72634.2 - 1.8e-22 79.7 0.0 4.1e-22 78.5 0.0 1.5 2 0 0 2 2 2 1 Calpain family cysteine protease TPR_11 PF13414.1 CAM72636.1 - 3.6e-22 77.7 8.8 1.3e-12 47.1 1.5 6.0 4 3 2 6 6 6 3 TPR repeat TPR_2 PF07719.12 CAM72636.1 - 5.3e-11 41.5 31.6 0.009 15.8 0.1 8.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 CAM72636.1 - 9.3e-11 40.8 17.4 0.00013 21.3 0.0 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat DnaJ PF00226.26 CAM72636.1 - 4.8e-09 35.8 0.7 1.3e-08 34.4 0.1 1.9 2 0 0 2 2 2 1 DnaJ domain TPR_7 PF13176.1 CAM72636.1 - 3.3e-05 23.3 5.8 0.32 10.9 0.1 5.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 CAM72636.1 - 0.00021 20.8 3.6 5.7 6.9 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 CAM72636.1 - 0.00033 20.5 23.4 0.0038 17.1 1.7 5.7 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 CAM72636.1 - 0.00042 20.1 29.9 0.21 11.4 1.5 5.8 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 CAM72636.1 - 0.025 15.2 45.8 0.45 11.2 1.7 6.3 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 CAM72636.1 - 0.061 13.9 0.7 0.061 13.9 0.5 7.7 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.1 CAM72636.1 - 0.57 10.5 8.4 23 5.4 0.1 4.8 6 0 0 6 6 3 0 Tetratricopeptide repeat XPC-binding PF09280.6 CAM72637.1 - 0.0033 16.8 0.7 0.0059 16.0 0.0 1.8 2 0 0 2 2 2 1 XPC-binding domain Nop14 PF04147.7 CAM72637.1 - 8.2 4.2 5.9 14 3.4 4.1 1.3 1 0 0 1 1 1 0 Nop14-like family zf-CCCH_2 PF14608.1 CAM72639.1 - 0.004 17.1 2.3 1.1 9.3 0.2 2.8 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type zf-CCCH PF00642.19 CAM72639.1 - 0.016 14.8 16.6 0.13 12.0 0.2 3.4 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pkinase PF00069.20 CAM72640.1 - 4.8e-73 245.5 0.0 6.1e-73 245.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM72640.1 - 4.2e-35 121.0 0.0 5.8e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM72640.1 - 3.8e-05 22.8 0.0 7.2e-05 21.8 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 CAM72640.1 - 0.009 15.1 1.6 0.019 14.0 1.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CAM72640.1 - 0.09 12.4 0.1 0.09 12.4 0.1 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family FeoB_N PF02421.13 CAM72640.1 - 0.14 11.4 0.2 0.27 10.5 0.1 1.4 1 1 0 1 1 1 0 Ferrous iron transport protein B KAR9 PF08580.5 CAM72640.1 - 3.2 5.9 6.1 4.8 5.3 4.3 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 LRR_4 PF12799.2 CAM72641.1 - 6.2e-12 44.8 0.1 0.00019 21.0 0.0 3.1 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 CAM72641.1 - 4.9e-08 32.7 0.1 1.1e-07 31.5 0.0 1.6 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 CAM72641.1 - 4.7e-06 26.2 0.7 4.4e-05 23.1 0.1 2.6 1 1 1 2 2 2 1 Leucine rich repeat BBIP10 PF14777.1 CAM72641.1 - 0.034 13.5 2.0 0.065 12.6 0.9 1.8 2 0 0 2 2 2 0 Cilia BBSome complex subunit 10 DUF1180 PF06679.7 CAM72641.1 - 0.056 13.3 1.2 0.089 12.6 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) LRR_7 PF13504.1 CAM72641.1 - 0.11 12.7 1.7 1.3e+02 3.4 0.0 4.8 5 0 0 5 5 5 0 Leucine rich repeat LRR_1 PF00560.28 CAM72641.1 - 0.19 11.8 0.5 46 4.6 0.0 3.7 3 1 0 3 3 3 0 Leucine Rich Repeat SSB PF00436.20 CAM72642.1 - 1.6e-05 24.7 0.0 2.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Single-strand binding protein family tRNA_anti-codon PF01336.20 CAM72642.1 - 0.044 13.6 0.0 0.088 12.6 0.0 1.6 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain EamA PF00892.15 CAM72645.1 - 4.5e-07 29.9 29.6 6.9e-06 26.1 2.5 4.6 5 0 0 5 5 5 2 EamA-like transporter family UAA PF08449.6 CAM72645.1 - 0.00017 20.5 0.9 0.00017 20.5 0.6 2.5 2 1 1 3 3 3 2 UAA transporter family EmrE PF13536.1 CAM72645.1 - 0.00065 19.8 3.1 0.00065 19.8 2.1 3.6 5 0 0 5 5 5 1 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 CAM72645.1 - 0.0014 17.7 0.2 0.0014 17.7 0.1 2.0 2 0 0 2 2 2 1 Nucleotide-sugar transporter TPT PF03151.11 CAM72645.1 - 4.1 7.0 27.4 0.046 13.3 7.1 3.2 3 1 0 3 3 3 0 Triose-phosphate Transporter family PIG-U PF06728.8 CAM72647.1 - 4.6e-06 25.7 21.8 2.7e-05 23.2 15.1 2.0 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U RNase_HII PF01351.13 CAM72648.1 - 3.4e-30 105.1 0.0 4.6e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII Alg14 PF08660.6 CAM72648.1 - 0.017 15.1 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like DUF3592 PF12158.3 CAM72649.1 - 5.8e-13 48.8 0.7 6.7e-13 48.6 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3592) ATP-synt_Eps PF04627.8 CAM72650.1 - 9.8e-05 21.8 0.2 0.00018 20.9 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain DnaJ PF00226.26 CAM72651.1 - 2.9e-23 81.3 0.6 7.1e-23 80.1 0.4 1.7 1 0 0 1 1 1 1 DnaJ domain DUF1373 PF07117.6 CAM72651.1 - 0.41 10.3 5.6 0.46 10.1 3.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1373) Ribosomal_S27 PF01599.14 CAM72652.1 - 1.5e-20 72.7 3.5 3.1e-20 71.7 2.5 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 CAM72652.1 - 1.1e-07 31.4 0.0 1.1e-06 28.1 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CAM72652.1 - 4.8e-07 29.0 0.0 1.3e-05 24.4 0.0 2.7 2 1 0 2 2 2 1 Ubiquitin family IBR PF01485.16 CAM72652.1 - 0.0022 17.7 0.8 0.0037 17.1 0.6 1.4 1 0 0 1 1 1 1 IBR domain IF4E PF01652.13 CAM72653.1 - 2.4e-08 33.6 0.0 2.9e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E CRAL_TRIO PF00650.15 CAM72654.1 - 2.6e-23 82.2 0.0 4e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CAP_GLY PF01302.20 CAM72654.1 - 4.3e-12 45.5 0.7 8.1e-12 44.6 0.5 1.4 1 0 0 1 1 1 1 CAP-Gly domain CRAL_TRIO_N PF03765.10 CAM72654.1 - 0.0042 17.2 0.1 0.0091 16.1 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain WD40 PF00400.27 CAM72655.1 - 1.2e-14 53.5 11.3 5.7e-06 26.0 0.2 6.0 7 0 0 7 7 7 3 WD domain, G-beta repeat GTP_EFTU PF00009.22 CAM72656.1 - 8.7e-60 201.3 0.0 1.5e-59 200.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 CAM72656.1 - 1.6e-23 82.3 0.0 3.8e-23 81.1 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 CAM72656.1 - 1.6e-20 72.7 0.0 4.2e-20 71.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.13 CAM72656.1 - 1.4e-15 56.9 0.0 3.5e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.20 CAM72656.1 - 4.4e-07 29.9 0.2 2.3e-06 27.6 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CAM72656.1 - 0.0064 16.4 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 CAM72656.1 - 0.015 14.4 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 AIG1 family DUF442 PF04273.8 CAM72656.1 - 0.04 13.7 0.0 2.3 8.1 0.0 2.9 3 0 0 3 3 3 0 Putative phosphatase (DUF442) FeoB_N PF02421.13 CAM72656.1 - 0.079 12.2 0.1 0.75 9.0 0.0 2.5 2 1 0 2 2 2 0 Ferrous iron transport protein B DUF465 PF04325.8 CAM72657.1 - 0.73 9.5 9.3 1.7 8.4 0.0 4.1 4 1 0 4 4 4 0 Protein of unknown function (DUF465) DUF641 PF04859.7 CAM72657.1 - 0.86 9.3 13.9 0.11 12.3 3.2 2.8 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) DUF972 PF06156.8 CAM72657.1 - 1.8 8.9 21.1 0.38 11.1 1.9 3.8 2 1 2 4 4 4 0 Protein of unknown function (DUF972) Pkinase PF00069.20 CAM72658.1 - 2.5e-78 262.8 0.0 2.8e-78 262.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM72658.1 - 1.6e-35 122.4 0.0 3.5e-35 121.3 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CAM72658.1 - 0.00084 19.1 0.2 0.014 15.1 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.17 CAM72658.1 - 0.068 12.5 0.0 0.12 11.6 0.0 1.5 1 1 0 1 1 1 0 RIO1 family Kinase-like PF14531.1 CAM72658.1 - 0.11 11.3 0.0 10 4.9 0.0 2.3 2 0 0 2 2 2 0 Kinase-like ubiquitin PF00240.18 CAM72659.1 - 3.4e-13 48.7 0.0 5.9e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 CAM72659.1 - 1.8e-07 30.8 0.3 7.1e-07 28.8 0.2 2.2 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.3 CAM72659.1 - 1.4e-06 27.8 0.0 2.2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RNA_pol_Rpb5_C PF01191.14 CAM72659.1 - 0.004 16.7 0.0 0.0088 15.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain Ubiquitin_2 PF14560.1 CAM72659.1 - 0.0059 16.8 0.0 0.018 15.2 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain YukD PF08817.5 CAM72659.1 - 0.0072 16.8 0.0 0.016 15.7 0.0 1.6 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD DUF2407 PF10302.4 CAM72659.1 - 0.0075 16.4 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 CAM72659.1 - 0.028 14.2 0.1 0.073 12.9 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like XPC-binding PF09280.6 CAM72659.1 - 0.076 12.4 19.7 0.29 10.6 13.6 2.1 1 0 0 1 1 1 0 XPC-binding domain TFIIA PF03153.8 CAM72659.1 - 2.9 7.7 8.3 3.2 7.5 5.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ODV-E18 PF10717.4 CAM72660.1 - 4.5 6.7 6.5 1.2 8.5 0.9 2.1 1 1 1 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 LSM PF01423.17 CAM72661.1 - 1.2e-06 27.9 0.0 1.8e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CAM72661.1 - 0.012 15.5 0.0 0.028 14.3 0.0 1.7 1 0 0 1 1 1 0 Ataxin 2 SM domain EFG_IV PF03764.13 CAM72661.1 - 0.044 13.3 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 Elongation factor G, domain IV PP2C PF00481.16 CAM72662.1 - 5.5e-70 235.6 0.8 6.9e-70 235.3 0.5 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CAM72662.1 - 0.001 18.5 0.0 0.0024 17.3 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 CAM72662.1 - 0.0031 17.2 0.0 0.13 11.9 0.0 2.2 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) Phage_lysis PF03245.8 CAM72663.1 - 0.12 12.3 1.2 0.17 11.8 0.3 1.6 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein Mito_carr PF00153.22 CAM72664.1 - 1.2e-90 297.3 21.5 3.9e-22 77.7 0.0 6.2 5 1 1 6 6 6 6 Mitochondrial carrier protein TPR_11 PF13414.1 CAM72665.1 - 8.9e-37 124.5 22.2 6.9e-19 67.2 2.4 5.3 3 2 2 5 5 5 4 TPR repeat DnaJ PF00226.26 CAM72665.1 - 2.3e-21 75.2 2.6 5.3e-21 74.1 0.4 2.5 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.12 CAM72665.1 - 7.3e-19 66.1 23.5 0.00022 20.8 0.0 8.1 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 CAM72665.1 - 3.4e-11 42.7 21.5 0.055 14.1 0.0 7.6 5 2 3 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.23 CAM72665.1 - 5.3e-11 41.6 22.2 0.0019 17.7 0.0 7.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 CAM72665.1 - 2.7e-10 40.4 17.0 0.00077 19.7 0.8 6.3 4 3 2 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 CAM72665.1 - 6.1e-09 36.3 22.8 1.6e-06 28.6 1.2 6.0 3 2 2 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 CAM72665.1 - 2.1e-08 33.7 9.0 0.00061 19.7 0.1 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 CAM72665.1 - 1e-06 28.5 13.7 0.0058 16.4 0.4 5.8 2 2 4 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 CAM72665.1 - 4.7e-06 25.9 11.9 0.06 13.1 0.1 5.8 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 CAM72665.1 - 2.6e-05 24.0 16.8 0.00033 20.5 0.8 4.9 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 CAM72665.1 - 0.00077 19.0 8.1 1.6 8.6 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat Cir_Bir_Yir PF06022.6 CAM72665.1 - 0.053 12.7 0.2 0.1 11.8 0.2 1.5 1 0 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir DASH_Dad3 PF08656.5 CAM72665.1 - 0.074 12.7 1.5 0.11 12.1 0.1 2.0 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF45 PF01863.12 CAM72665.1 - 0.14 11.9 4.1 0.2 11.4 2.3 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF45 Phage_term_smal PF05944.7 CAM72665.1 - 0.14 11.8 2.6 2.4 7.8 0.2 2.7 2 0 0 2 2 2 0 Phage small terminase subunit Fis1_TPR_C PF14853.1 CAM72665.1 - 0.18 11.7 3.7 1 9.2 0.2 3.5 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat DUF972 PF06156.8 CAM72665.1 - 0.35 11.2 2.1 8.8 6.7 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF972) zf-C2HC_2 PF13913.1 CAM72666.1 - 8.4e-16 57.1 6.4 2.8e-10 39.5 0.9 2.3 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.1 CAM72666.1 - 0.0025 18.0 0.7 1 9.7 0.1 2.3 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CAM72666.1 - 0.24 11.8 4.3 15 6.2 0.9 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CAM72666.1 - 0.46 10.4 5.1 2.2 8.3 0.5 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 CAM72666.1 - 0.49 10.8 4.4 8.7 6.9 0.9 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Sgf11 PF08209.6 CAM72666.1 - 1.5 8.2 4.4 2.8 7.3 0.8 2.5 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-Apc11 PF12861.2 CAM72667.1 - 0.018 14.8 0.8 0.032 14.0 0.6 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Dus PF01207.12 CAM72668.1 - 4e-35 121.1 0.8 5.8e-31 107.4 0.1 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) Sec1 PF00995.18 CAM72669.1 - 5.1e-131 438.0 0.1 5.9e-131 437.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family YPEB PF14620.1 CAM72670.1 - 0.04 12.9 0.0 0.06 12.3 0.0 1.2 1 0 0 1 1 1 0 YpeB sporulation W2 PF02020.13 CAM72671.1 - 0.15 12.0 0.2 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon TFIIA_gamma_C PF02751.9 CAM72672.1 - 0.015 15.0 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit Aa_trans PF01490.13 CAM72673.1 - 2.7e-64 217.1 16.1 3.2e-64 216.9 11.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CAM72673.1 - 1.7e-07 30.4 16.3 1.7e-07 30.4 11.3 2.0 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family TerB-C PF15615.1 CAM72674.1 - 0.075 13.2 3.7 0.11 12.7 1.6 1.8 2 0 0 2 2 2 0 TerB-C domain PDZ_2 PF13180.1 CAM72675.1 - 2.9e-05 23.8 0.0 7.6e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 CAM72675.1 - 0.00081 19.5 0.5 0.0024 18.0 0.0 1.9 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) APG17 PF04108.7 CAM72675.1 - 0.046 12.5 8.1 0.12 11.1 1.2 2.1 1 1 1 2 2 2 0 Autophagy protein Apg17 DUF3391 PF11871.3 CAM72675.1 - 0.27 11.4 5.2 0.26 11.5 1.4 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF3391) Baculo_PEP_C PF04513.7 CAM72675.1 - 1.7 8.4 4.9 11 5.7 3.0 2.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Macoilin PF09726.4 CAM72676.1 - 0.49 8.6 8.3 0.65 8.2 5.8 1.1 1 0 0 1 1 1 0 Transmembrane protein PIP5K PF01504.13 CAM72678.1 - 5.1e-62 209.2 0.0 6.6e-62 208.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF106 PF01956.11 CAM72679.1 - 1.6e-46 157.8 3.5 1.6e-46 157.8 2.4 1.4 2 0 0 2 2 2 1 Integral membrane protein DUF106 Nop10p PF04135.7 CAM72681.1 - 2.9e-21 74.9 0.3 3.2e-21 74.7 0.2 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family RNase_HII PF01351.13 CAM72682.1 - 1.9e-24 86.4 0.0 3.9e-15 56.0 0.0 3.0 1 1 0 2 2 2 2 Ribonuclease HII Proteasome PF00227.21 CAM72684.1 - 9.1e-26 90.3 0.0 1.1e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit ESCRT-II PF05871.7 CAM72685.1 - 7.2e-13 48.6 0.0 3.3e-12 46.5 0.0 1.9 1 1 0 1 1 1 1 ESCRT-II complex subunit DUF3223 PF11523.3 CAM72685.1 - 0.064 13.5 0.1 1.3 9.4 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3223) MiaE_2 PF13794.1 CAM72685.1 - 0.12 11.7 0.1 15 4.9 0.0 2.2 2 0 0 2 2 2 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like NUDIX PF00293.23 CAM72686.1 - 7.4e-16 58.0 0.0 6e-15 55.0 0.0 2.3 2 1 1 3 3 3 1 NUDIX domain TFIIS_M PF07500.9 CAM72688.1 - 0.00025 21.1 2.7 0.0006 19.8 1.9 1.6 1 1 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain Pkinase_C PF00433.19 CAM72688.1 - 0.23 12.0 2.7 0.77 10.3 1.9 2.0 1 0 0 1 1 1 0 Protein kinase C terminal domain CH PF00307.26 CAM72689.1 - 0.098 12.7 0.0 24 5.0 0.0 2.8 2 0 0 2 2 2 0 Calponin homology (CH) domain FGGY_N PF00370.16 CAM72690.1 - 4.8e-77 258.5 0.0 6.3e-77 258.1 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 CAM72690.1 - 1.6e-30 106.2 0.4 4e-30 104.9 0.1 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.15 CAM72690.1 - 0.0034 16.7 0.0 3.1 6.9 0.0 3.0 2 1 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family DUF1609 PF07753.6 CAM72690.1 - 0.11 11.8 0.1 0.2 10.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1609) Paf67 PF10255.4 CAM72691.1 - 3e-82 276.6 0.0 4e-82 276.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 ADIP PF11559.3 CAM72692.1 - 1.5e-07 31.3 13.9 1.5e-07 31.3 9.6 1.8 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding DUF4164 PF13747.1 CAM72692.1 - 4.9e-06 26.5 6.5 4.9e-06 26.5 4.5 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF4164) HAP1_N PF04849.8 CAM72692.1 - 0.001 18.0 7.7 0.001 18.0 5.4 1.4 2 0 0 2 2 2 1 HAP1 N-terminal conserved region CENP-F_leu_zip PF10473.4 CAM72692.1 - 0.016 15.0 20.5 0.016 15.0 14.2 2.2 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.16 CAM72692.1 - 0.021 14.7 1.5 0.021 14.7 1.1 3.2 3 1 0 3 3 3 0 bZIP transcription factor Stonin2_N PF12016.3 CAM72692.1 - 0.03 13.4 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 Stonin 2 DUF3840 PF12944.2 CAM72692.1 - 0.053 13.3 1.6 0.058 13.2 0.3 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF3840) FlaC_arch PF05377.6 CAM72692.1 - 0.08 12.8 1.0 0.08 12.8 0.7 2.3 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.5 CAM72692.1 - 0.089 12.9 9.0 0.095 12.8 4.4 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4279 PF14106.1 CAM72692.1 - 0.15 11.9 0.8 0.31 10.9 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) DUF342 PF03961.8 CAM72692.1 - 0.16 10.3 7.7 0.39 9.0 5.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DUF1664 PF07889.7 CAM72692.1 - 0.34 10.7 3.1 0.45 10.3 1.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.17 CAM72692.1 - 0.37 10.8 16.6 0.062 13.3 7.5 2.3 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.10 CAM72692.1 - 0.62 9.5 21.9 1.1 8.8 5.3 3.4 2 1 0 3 3 3 0 Septum formation initiator V_ATPase_I PF01496.14 CAM72692.1 - 0.75 7.5 5.1 0.99 7.1 3.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 CAM72692.1 - 0.83 10.0 14.2 8.4 6.7 4.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF972) RTBV_P46 PF06216.6 CAM72692.1 - 0.89 8.3 3.5 1.2 7.8 2.5 1.2 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein TBPIP PF07106.8 CAM72692.1 - 1 8.8 12.4 0.4 10.2 6.8 1.7 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GAS PF13851.1 CAM72692.1 - 1.1 8.4 20.5 5.3 6.1 12.8 2.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4407 PF14362.1 CAM72692.1 - 2.8 6.8 8.2 12 4.6 4.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4446 PF14584.1 CAM72692.1 - 5 6.9 12.6 0.17 11.6 1.5 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) T2SM PF04612.7 CAM72692.1 - 5.9 6.6 16.1 3 7.6 3.8 2.3 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M APG6 PF04111.7 CAM72692.1 - 5.9 5.8 19.0 5.8 5.8 11.4 2.1 2 1 0 2 2 2 0 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 CAM72692.1 - 6.2 6.5 21.9 4.8 6.9 3.2 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein FKBP_C PF00254.23 CAM72693.1 - 9.4e-27 92.8 0.0 1.2e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Glycos_transf_2 PF00535.21 CAM72694.1 - 2.5e-31 108.6 0.0 3.1e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CAM72694.1 - 6.1e-07 29.4 0.0 8e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 CAM72694.1 - 0.011 14.8 0.0 0.014 14.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 CAM72694.1 - 0.023 15.0 0.0 0.042 14.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 DAO PF01266.19 CAM72694.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase SET PF00856.23 CAM72695.1 - 1.5e-09 38.3 0.0 8.9e-08 32.6 0.0 2.3 2 0 0 2 2 2 1 SET domain RimK PF08443.6 CAM72695.1 - 0.0013 18.2 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Propep_M14 PF02244.11 CAM72695.1 - 0.037 13.6 0.0 0.08 12.6 0.0 1.5 1 0 0 1 1 1 0 Carboxypeptidase activation peptide Peptidase_S24 PF00717.18 CAM72696.1 - 6.1e-06 25.7 0.0 1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 CAM72696.1 - 0.0026 17.2 0.0 0.0046 16.4 0.0 1.4 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 GTP_EFTU PF00009.22 CAM72697.1 - 2.4e-61 206.4 0.4 3.7e-61 205.8 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CAM72697.1 - 2.8e-36 123.7 0.0 7.3e-36 122.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 CAM72697.1 - 7.3e-21 73.8 0.0 3.2e-20 71.7 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.1 CAM72697.1 - 7.8e-14 51.2 0.1 3.5e-13 49.2 0.0 2.0 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 CAM72697.1 - 3.2e-13 49.5 0.1 8.8e-13 48.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU PF00009.22 CAM72698.1 - 2.4e-61 206.4 0.4 3.7e-61 205.8 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CAM72698.1 - 2.8e-36 123.7 0.0 7.3e-36 122.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 CAM72698.1 - 7.3e-21 73.8 0.0 3.2e-20 71.7 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.1 CAM72698.1 - 7.8e-14 51.2 0.1 3.5e-13 49.2 0.0 2.0 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 CAM72698.1 - 3.2e-13 49.5 0.1 8.8e-13 48.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 DUF3617 PF12276.3 CAM72700.1 - 0.11 11.9 0.7 0.32 10.4 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3617) His_Phos_1 PF00300.17 CAM72701.1 - 2e-28 99.4 0.0 6.7e-28 97.7 0.0 1.9 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 CAM72701.1 - 0.053 12.8 0.0 0.18 11.1 0.0 1.8 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) PUB PF09409.5 CAM72703.1 - 1.1e-16 60.3 0.0 2.8e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 PUB domain DUF971 PF06155.7 CAM72703.1 - 0.36 11.2 2.0 1.1 9.7 1.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF971) Pox_MCEL PF03291.11 CAM72704.1 - 2.2e-30 105.6 0.0 1.9e-29 102.6 0.0 1.9 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_23 PF13489.1 CAM72704.1 - 0.0099 15.6 0.0 0.03 14.0 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 CAM72704.1 - 0.013 14.4 0.0 0.35 9.7 0.1 2.1 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_12 PF08242.7 CAM72704.1 - 0.065 13.7 0.0 0.32 11.4 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain IMS PF00817.15 CAM72706.1 - 5e-34 117.2 0.1 1.1e-33 116.0 0.1 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 CAM72706.1 - 1.1e-05 25.3 0.0 3.9e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain LCM PF04072.9 CAM72708.1 - 7e-27 94.1 0.0 8.8e-27 93.8 0.0 1.1 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase TPR_11 PF13414.1 CAM72709.1 - 4.2e-50 167.2 15.2 6.5e-17 60.9 0.1 4.1 2 2 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 CAM72709.1 - 3.2e-41 137.2 14.2 5.9e-08 31.9 0.0 6.3 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.12 CAM72709.1 - 1.5e-35 118.1 10.8 5.4e-09 35.2 0.0 6.3 6 1 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 CAM72709.1 - 7.8e-22 75.3 9.0 9.9e-08 31.2 0.0 6.2 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 CAM72709.1 - 3e-18 65.5 7.1 1.7e-05 24.6 0.1 4.3 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.1 CAM72709.1 - 9.9e-17 59.3 4.2 0.00012 21.5 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 CAM72709.1 - 2.3e-16 58.8 1.5 5.3e-05 23.4 0.0 5.5 2 2 4 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 CAM72709.1 - 6e-16 58.6 3.2 0.014 16.0 0.0 4.2 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 CAM72709.1 - 5.2e-15 54.3 6.0 0.014 15.5 0.1 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 CAM72709.1 - 5.2e-12 45.3 8.6 0.00015 22.0 0.1 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 CAM72709.1 - 4.2e-11 43.0 6.7 0.00094 19.4 0.0 4.9 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 CAM72709.1 - 6.3e-10 38.7 0.2 0.002 17.9 0.0 4.0 3 1 0 4 4 4 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 CAM72709.1 - 5.6e-08 31.9 4.5 0.013 14.7 0.0 4.8 5 0 0 5 5 5 2 SHNi-TPR MIT PF04212.13 CAM72709.1 - 6.2e-08 32.4 8.8 0.027 14.3 0.2 4.4 4 0 0 4 4 4 3 MIT (microtubule interacting and transport) domain Apc3 PF12895.2 CAM72709.1 - 1.2e-07 31.7 6.4 0.00023 21.2 0.0 3.0 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 CAM72709.1 - 4.7e-06 26.3 1.3 0.32 10.9 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.7 CAM72709.1 - 7.7e-05 22.3 5.6 0.079 12.7 0.1 3.9 3 1 0 3 3 3 1 Tetratricopeptide repeat DUF3856 PF12968.2 CAM72709.1 - 0.00013 21.8 1.4 0.12 12.1 0.0 3.4 3 1 0 3 3 3 1 Domain of Unknown Function (DUF3856) Fis1_TPR_C PF14853.1 CAM72709.1 - 0.0004 20.2 0.6 0.11 12.4 0.0 4.3 4 1 1 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat SPO22 PF08631.5 CAM72709.1 - 0.00072 18.7 1.4 0.19 10.7 0.1 3.1 3 0 0 3 3 3 1 Meiosis protein SPO22/ZIP4 like DUF2225 PF09986.4 CAM72709.1 - 0.013 15.0 4.1 0.39 10.1 0.1 2.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Ribosomal_S7 PF00177.16 CAM72709.1 - 0.061 12.8 0.4 0.49 9.9 0.1 2.2 1 1 1 2 2 2 0 Ribosomal protein S7p/S5e Egg_lysin PF01303.12 CAM72709.1 - 0.1 12.6 1.0 0.3 11.0 0.1 2.0 2 1 0 2 2 2 0 Egg lysin (Sperm-lysin) Sel1 PF08238.7 CAM72709.1 - 0.23 12.1 12.4 1.5 9.5 0.3 4.6 3 1 1 4 4 4 0 Sel1 repeat DUF3560 PF12083.3 CAM72709.1 - 0.43 10.6 2.8 3.9 7.5 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3560) SAP PF02037.22 CAM72710.1 - 2.7e-12 45.8 0.5 5.2e-12 44.9 0.4 1.5 1 0 0 1 1 1 1 SAP domain DUF2407 PF10302.4 CAM72710.1 - 0.071 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain MRI PF15325.1 CAM72710.1 - 0.69 10.8 4.1 2.9 8.9 1.9 2.5 2 0 0 2 2 2 0 Modulator of retrovirus infection FGGY_C PF02782.11 CAM72711.1 - 3.3e-36 124.7 0.1 5.7e-36 123.9 0.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 CAM72711.1 - 2.8e-06 26.8 0.0 8.2e-06 25.3 0.0 1.8 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain PUF PF00806.14 CAM72712.1 - 5.5e-33 110.5 11.5 6.4e-06 25.3 0.1 7.4 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat NatB_MDM20 PF09797.4 CAM72712.1 - 0.0011 17.7 0.2 0.0021 16.8 0.1 1.4 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit Amidohydro_4 PF13147.1 CAM72713.1 - 2e-18 67.3 0.0 2.9e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 CAM72713.1 - 8.4e-05 22.3 0.4 0.034 13.7 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 CAM72713.1 - 0.00012 21.4 0.1 0.031 13.4 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_5 PF13594.1 CAM72713.1 - 0.0006 19.5 0.0 0.0015 18.3 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Histone PF00125.19 CAM72715.1 - 3.7e-14 52.5 0.8 4.5e-14 52.3 0.6 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CAM72715.1 - 2.6e-05 24.1 0.1 4.3e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 CAM72715.1 - 7.4e-05 22.6 0.1 0.00011 22.0 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.8 CAM72715.1 - 0.00064 19.4 0.0 0.00081 19.0 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 CAM72715.1 - 0.0013 18.5 0.0 0.0014 18.4 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit PCP_red PF08369.5 CAM72715.1 - 0.033 14.0 1.0 0.064 13.1 0.3 1.9 2 1 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit FbpA PF05833.6 CAM72715.1 - 0.049 12.1 0.0 0.057 11.9 0.0 1.0 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF4400 PF14348.1 CAM72715.1 - 0.092 12.1 0.3 0.13 11.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) His_Phos_1 PF00300.17 CAM72717.1 - 1.1e-13 51.6 1.2 3.1e-12 46.8 0.9 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) 3HCDH_N PF02737.13 CAM72717.1 - 0.09 12.4 0.2 0.51 9.9 0.1 2.2 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF501 PF04417.7 CAM72717.1 - 0.14 12.0 0.4 0.26 11.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF501) RCC1 PF00415.13 CAM72718.1 - 3e-39 132.9 11.1 7.5e-10 38.8 0.1 7.8 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CAM72718.1 - 3e-21 74.4 20.2 3.7e-06 26.4 2.0 7.5 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat TatD_DNase PF01026.16 CAM72719.1 - 3.4e-25 88.7 0.0 1.9e-24 86.2 0.0 1.9 2 0 0 2 2 2 1 TatD related DNase TPR_11 PF13414.1 CAM72720.1 - 6.9e-06 25.6 8.0 0.0054 16.3 1.3 3.0 2 1 0 2 2 2 2 TPR repeat TPR_16 PF13432.1 CAM72720.1 - 9.6e-06 26.1 9.6 0.53 11.0 1.5 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat SHNi-TPR PF10516.4 CAM72720.1 - 0.00047 19.3 1.3 0.0011 18.1 0.9 1.6 1 0 0 1 1 1 1 SHNi-TPR TPR_2 PF07719.12 CAM72720.1 - 0.00082 19.1 12.9 0.59 10.1 0.7 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 CAM72720.1 - 0.0017 18.2 14.8 0.51 10.3 1.1 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 CAM72720.1 - 0.012 15.1 6.2 8.8 6.1 0.3 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 CAM72720.1 - 0.032 14.0 5.2 4.4 7.3 0.7 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat SAPS PF04499.10 CAM72720.1 - 0.11 11.1 3.6 0.15 10.6 2.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TRAP_alpha PF03896.11 CAM72720.1 - 3.5 6.5 11.5 6.4 5.6 8.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Strep_SA_rep PF06696.6 CAM72720.1 - 5 7.0 11.1 3.4 7.5 2.6 2.7 2 0 0 2 2 2 0 Streptococcal surface antigen repeat RR_TM4-6 PF06459.7 CAM72720.1 - 5 6.9 15.2 0.91 9.3 7.7 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Spore_coat_CotO PF14153.1 CAM72720.1 - 6.5 6.1 10.4 18 4.7 7.2 1.7 1 0 0 1 1 1 0 Spore coat protein CotO TPR_6 PF13174.1 CAM72720.1 - 7.3 7.2 10.6 30 5.3 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_M14 PF00246.19 CAM72721.1 - 1.9e-23 83.4 0.0 5.1e-23 82.0 0.0 1.6 1 1 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.9 CAM72721.1 - 5.6e-06 25.4 0.1 8.9e-06 24.7 0.1 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family V-SNARE_C PF12352.3 CAM72722.1 - 1.1e-06 28.6 1.1 1.1e-06 28.6 0.8 1.8 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus RD3 PF14473.1 CAM72722.1 - 0.082 12.3 0.5 0.3 10.5 0.0 2.0 2 0 0 2 2 2 0 RD3 protein HrpB7 PF09486.5 CAM72722.1 - 6.9 6.5 15.7 2.2 8.2 6.0 2.3 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Rieske PF00355.21 CAM72724.1 - 0.063 12.8 0.0 0.14 11.7 0.0 1.6 1 1 0 1 1 1 0 Rieske [2Fe-2S] domain NTP_transf_2 PF01909.18 CAM72725.1 - 1.6e-07 31.5 0.0 2.9e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyltransferase domain Proteasome PF00227.21 CAM72726.1 - 9.1e-26 90.3 0.3 2.6e-25 88.8 0.2 1.6 1 1 0 1 1 1 1 Proteasome subunit CDC73 PF05179.9 CAM72727.1 - 1.8e-26 93.1 0.2 4.5e-26 91.8 0.1 1.4 1 1 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family Bromodomain PF00439.20 CAM72727.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain Herpes_UL6 PF01763.11 CAM72728.2 - 0.066 11.3 4.9 0.11 10.6 3.4 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like TACC PF05010.9 CAM72730.1 - 1.1e-06 28.5 2.9 1.3e-06 28.3 0.7 2.0 1 1 1 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC) GSCFA PF08885.6 CAM72730.1 - 0.065 12.7 0.2 0.14 11.7 0.1 1.5 1 1 0 1 1 1 0 GSCFA family FAM92 PF06730.6 CAM72730.1 - 0.17 11.1 9.3 0.06 12.6 3.3 2.3 3 0 0 3 3 3 0 FAM92 protein Atg14 PF10186.4 CAM72730.1 - 0.17 10.7 11.5 0.26 10.1 0.8 2.4 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 IFT46_B_C PF12317.3 CAM72730.1 - 0.18 11.1 0.9 0.27 10.5 0.2 1.6 2 0 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Bacillus_HBL PF05791.6 CAM72730.1 - 0.35 10.2 10.3 0.24 10.7 0.1 2.9 3 1 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) AAA_13 PF13166.1 CAM72730.1 - 0.49 8.7 8.6 0.62 8.4 4.7 1.8 1 1 1 2 2 2 0 AAA domain PilJ PF13675.1 CAM72730.1 - 0.8 10.0 6.8 0.54 10.5 0.3 3.0 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term OmpH PF03938.9 CAM72730.1 - 1.4 8.8 7.3 2.4 8.0 0.0 2.6 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Remorin_C PF03763.8 CAM72730.1 - 2.7 7.5 7.5 2.7 7.5 2.0 2.6 1 1 1 2 2 2 0 Remorin, C-terminal region Telomerase_RBD PF12009.3 CAM72732.1 - 2.9e-26 91.9 0.1 5.3e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 CAM72732.1 - 0.00021 20.7 0.0 0.0007 19.0 0.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4282 PF14110.1 CAM72733.1 - 3.7 7.7 11.3 36 4.6 7.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4282) AdoHcyase PF05221.12 CAM72734.1 - 1.2e-142 473.6 0.0 1.4e-142 473.4 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 CAM72734.1 - 8.6e-87 289.0 1.9 1.3e-86 288.5 1.3 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 CAM72734.1 - 2.2e-10 39.9 0.0 4.7e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 CAM72734.1 - 3.4e-05 23.2 0.0 5.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 CAM72734.1 - 5.5e-05 23.1 0.3 0.00033 20.6 0.1 2.4 2 1 0 2 2 2 1 TrkA-N domain NAD_binding_7 PF13241.1 CAM72734.1 - 0.00065 19.9 0.1 0.0015 18.7 0.1 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding ELFV_dehydrog PF00208.16 CAM72734.1 - 0.0066 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase UDPG_MGDP_dh_N PF03721.9 CAM72734.1 - 0.11 11.9 0.3 0.17 11.2 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.15 CAM72734.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 CAM72734.1 - 0.12 11.4 0.4 0.48 9.4 0.3 1.9 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain WD40 PF00400.27 CAM72737.1 - 1.8e-19 68.7 1.4 1.5e-07 31.0 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Gasdermin PF04598.7 CAM72738.1 - 0.0013 17.5 2.6 0.002 16.9 1.8 1.2 1 0 0 1 1 1 1 Gasdermin family LRR_6 PF13516.1 CAM72738.1 - 0.14 12.3 0.4 19 5.6 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich repeat HAP2-GCS1 PF10699.4 CAM72739.1 - 2.5e-16 59.3 0.1 9.9e-16 57.4 0.0 2.1 2 0 0 2 2 2 1 Male gamete fusion factor Snf7 PF03357.16 CAM72740.1 - 1.7e-29 102.3 32.0 1.7e-29 102.3 22.2 1.5 2 0 0 2 2 2 1 Snf7 ODR4-like PF14778.1 CAM72740.1 - 0.0023 16.6 3.1 0.0027 16.4 2.2 1.2 1 0 0 1 1 1 1 Olfactory receptor 4-like Mst1_SARAH PF11629.3 CAM72740.1 - 0.04 13.7 1.2 0.04 13.7 0.8 2.7 3 0 0 3 3 3 0 C terminal SARAH domain of Mst1 Noc2 PF03715.8 CAM72740.1 - 0.13 11.1 2.6 0.16 10.7 1.8 1.3 1 1 0 1 1 1 0 Noc2p family Exonuc_VII_L PF02601.10 CAM72740.1 - 2.2 7.4 13.8 2.6 7.1 9.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.4 CAM72740.1 - 6.6 5.5 12.9 10 4.9 8.9 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SURF6 PF04935.7 CAM72740.1 - 6.6 5.9 20.5 0.28 10.4 4.3 2.3 1 1 0 2 2 2 0 Surfeit locus protein 6 tRNA-synt_2b PF00587.20 CAM72741.1 - 3.7e-54 182.9 0.2 6.2e-54 182.1 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CAM72741.1 - 1.2e-17 63.6 0.0 2.4e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain zf-C3HC4_3 PF13920.1 CAM72742.1 - 4.3e-18 64.7 31.5 4.8e-13 48.5 8.2 4.5 4 1 1 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAM72742.1 - 3.4e-07 30.1 32.8 3.3e-05 23.8 9.8 4.1 4 1 1 5 5 5 3 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAM72742.1 - 0.00015 21.4 12.3 0.00015 21.4 8.5 3.8 4 0 0 4 4 4 2 zinc-RING finger domain HisKA_3 PF07730.8 CAM72743.1 - 0.01 16.1 1.1 0.02 15.2 0.7 1.5 1 0 0 1 1 1 0 Histidine kinase AIP3 PF03915.8 CAM72743.1 - 0.034 13.0 0.1 0.04 12.8 0.0 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 bZIP_2 PF07716.10 CAM72743.1 - 0.13 12.0 8.6 0.7 9.7 2.5 2.3 2 0 0 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.16 CAM72743.1 - 0.25 11.3 2.9 11 6.0 0.8 2.2 2 0 0 2 2 2 0 bZIP transcription factor GCV_T PF01571.16 CAM72744.1 - 1.6e-63 213.8 0.2 2e-63 213.5 0.2 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 CAM72744.1 - 1.1e-18 67.0 0.1 2.4e-18 65.9 0.1 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 CAM72744.1 - 0.0029 17.4 0.0 0.12 12.2 0.0 2.3 1 1 1 2 2 2 2 Sarcosine oxidase, gamma subunit family GCV_T PF01571.16 CAM72745.1 - 1.6e-63 213.8 0.2 2e-63 213.5 0.2 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 CAM72745.1 - 1.1e-18 67.0 0.1 2.4e-18 65.9 0.1 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 CAM72745.1 - 0.0029 17.4 0.0 0.12 12.2 0.0 2.3 1 1 1 2 2 2 2 Sarcosine oxidase, gamma subunit family CH PF00307.26 CAM72746.1 - 0.00025 21.0 0.0 0.00055 19.9 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 CAM72746.1 - 0.031 13.9 0.0 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain MORN PF02493.15 CAM72747.1 - 8.2e-18 62.9 56.0 4.9e-05 22.8 0.8 9.0 9 0 0 9 9 9 7 MORN repeat DUF448 PF04296.8 CAM72747.1 - 0.0029 17.1 0.3 3.4 7.3 0.0 3.7 3 0 0 3 3 3 1 Protein of unknown function (DUF448) DUF2766 PF10964.3 CAM72747.1 - 0.054 13.3 0.0 0.12 12.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2766) NAC PF01849.13 CAM72748.1 - 7.2e-19 67.0 0.0 9.5e-19 66.6 0.0 1.2 1 0 0 1 1 1 1 NAC domain Ribosomal_L1 PF00687.16 CAM72749.1 - 5e-47 160.0 3.6 5.8e-47 159.8 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ribosomal_S27e PF01667.12 CAM72750.1 - 8.4e-22 76.4 3.1 1.1e-21 76.1 2.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 CAM72750.1 - 0.0011 18.8 1.5 0.0015 18.3 1.0 1.2 1 0 0 1 1 1 1 IBR domain FYVE_2 PF02318.11 CAM72750.1 - 0.0085 15.9 1.4 0.01 15.7 1.0 1.1 1 0 0 1 1 1 1 FYVE-type zinc finger Zn_Tnp_IS1595 PF12760.2 CAM72750.1 - 0.0091 15.7 2.0 0.014 15.2 1.4 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Cbl_N3 PF02762.9 CAM72750.1 - 0.047 13.3 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain HypA PF01155.14 CAM72750.1 - 0.11 12.1 1.4 0.14 11.8 1.0 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_4 PF13717.1 CAM72750.1 - 0.18 11.5 4.4 3.2 7.5 3.1 2.3 1 1 0 1 1 1 0 zinc-ribbon domain Elf1 PF05129.8 CAM72750.1 - 0.19 11.4 2.9 0.27 10.9 2.0 1.2 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zinc_ribbon_5 PF13719.1 CAM72750.1 - 0.3 10.6 4.6 4.5 6.9 3.2 2.3 1 1 0 1 1 1 0 zinc-ribbon domain Zn_Tnp_IS1 PF03811.8 CAM72750.1 - 0.32 10.5 7.8 2.2 7.8 5.4 2.2 1 1 0 1 1 1 0 InsA N-terminal domain Mu-like_Com PF10122.4 CAM72750.1 - 0.39 9.7 6.7 0.36 9.9 0.1 2.3 1 1 1 2 2 2 0 Mu-like prophage protein Com OrfB_Zn_ribbon PF07282.6 CAM72750.1 - 1.7 8.3 6.5 1.1 8.9 1.6 2.0 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Ribosomal_L34e PF01199.13 CAM72751.1 - 1.2e-27 95.9 3.9 1.2e-27 95.9 2.7 2.2 2 1 0 2 2 2 1 Ribosomal protein L34e RecA PF00154.16 CAM72751.1 - 0.032 13.3 2.2 0.04 12.9 1.6 1.1 1 0 0 1 1 1 0 recA bacterial DNA recombination protein PGM_PMM_III PF02880.11 CAM72751.1 - 0.25 11.3 1.2 0.39 10.7 0.3 1.8 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III NARP1 PF12569.3 CAM72751.1 - 0.52 9.0 8.9 0.57 8.8 6.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 tRNA_int_endo PF01974.12 CAM72752.1 - 7.5e-15 54.5 0.0 1.2e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain DUF498 PF04430.9 CAM72753.1 - 3e-23 81.4 0.0 5.2e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) FtsK_SpoIIIE PF01580.13 CAM72754.1 - 0.00035 20.1 0.0 0.00072 19.0 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family Clp1 PF06807.9 CAM72754.1 - 0.0014 18.3 0.0 0.0036 17.0 0.0 1.6 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 AAA_19 PF13245.1 CAM72754.1 - 0.015 15.0 0.0 0.044 13.5 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain zf-C2HC PF01530.13 CAM72755.1 - 0.14 11.9 0.4 0.29 10.8 0.3 1.5 1 0 0 1 1 1 0 Zinc finger, C2HC type Pkinase PF00069.20 CAM72757.1 - 4e-53 180.2 0.0 4.2e-52 176.8 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM72757.1 - 8.8e-30 103.6 0.0 3.8e-29 101.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM72757.1 - 0.00017 20.6 0.0 0.00065 18.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like PAS PF00989.19 CAM72757.1 - 0.00031 20.5 0.0 0.0016 18.1 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 CAM72757.1 - 0.0065 16.8 0.0 0.02 15.2 0.0 1.9 1 0 0 1 1 1 1 PAS domain RIO1 PF01163.17 CAM72757.1 - 0.0068 15.7 0.0 0.061 12.6 0.0 2.2 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 CAM72757.1 - 0.02 14.6 0.7 0.051 13.3 0.0 2.0 3 0 0 3 3 3 0 Phosphotransferase enzyme family Amastin PF07344.6 CAM72757.1 - 0.11 12.0 3.2 0.25 10.9 2.2 1.5 1 0 0 1 1 1 0 Amastin surface glycoprotein EF-hand_1 PF00036.27 CAM72758.1 - 3.9e-27 91.4 5.4 2.3e-07 29.6 0.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CAM72758.1 - 1.3e-25 89.2 0.8 2e-14 53.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CAM72758.1 - 7.4e-22 75.2 3.2 4.5e-06 26.1 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 CAM72758.1 - 1.7e-20 72.3 4.4 2.2e-10 40.0 0.1 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 CAM72758.1 - 1.1e-18 65.6 4.1 1.5e-05 24.1 0.6 4.4 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 CAM72758.1 - 1.2e-06 28.2 0.7 0.02 14.8 0.0 2.9 2 2 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CAM72758.1 - 5e-05 22.9 2.4 0.0047 16.6 0.1 2.4 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand NUDIX PF00293.23 CAM72760.1 - 1.1e-11 44.5 0.0 1.6e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF1619 PF07773.6 CAM72761.1 - 2e-84 283.9 0.2 5.3e-82 275.9 0.3 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1619) WD40 PF00400.27 CAM72763.1 - 1.6e-15 56.3 12.5 6e-05 22.7 0.1 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat GAS PF13851.1 CAM72764.1 - 0.059 12.5 2.1 0.084 12.0 1.2 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4448 PF14610.1 CAM72765.1 - 0.00074 19.0 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Shisa PF13908.1 CAM72765.1 - 0.00095 19.3 0.8 0.00095 19.3 0.6 1.7 2 0 0 2 2 1 1 Wnt and FGF inhibitory regulator Herpes_gE PF02480.11 CAM72765.1 - 0.0011 17.3 0.2 0.0015 16.9 0.1 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E TMEM154 PF15102.1 CAM72765.1 - 0.0043 16.7 0.0 0.0085 15.8 0.0 1.5 1 0 0 1 1 1 1 TMEM154 protein family Selenoprotein_S PF06936.6 CAM72765.1 - 0.006 16.1 1.0 0.008 15.7 0.7 1.2 1 0 0 1 1 1 1 Selenoprotein S (SelS) IncA PF04156.9 CAM72765.1 - 0.0066 16.0 3.6 0.011 15.3 2.5 1.3 1 0 0 1 1 1 1 IncA protein DUF3481 PF11980.3 CAM72765.1 - 0.021 14.6 0.2 0.046 13.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) Neur_chan_memb PF02932.11 CAM72765.1 - 0.026 14.4 0.1 0.032 14.1 0.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FixQ PF05545.6 CAM72765.1 - 0.03 13.9 0.3 0.089 12.4 0.1 1.9 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ CD34_antigen PF06365.7 CAM72765.1 - 0.039 13.5 3.0 0.077 12.6 0.8 2.0 1 1 1 2 2 2 0 CD34/Podocalyxin family DUF4229 PF14012.1 CAM72765.1 - 0.039 13.8 0.1 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) Adeno_E3_CR2 PF02439.10 CAM72765.1 - 0.043 13.3 2.6 0.09 12.3 1.8 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 AJAP1_PANP_C PF15298.1 CAM72765.1 - 0.053 13.3 0.0 0.092 12.6 0.0 1.5 1 0 0 1 1 1 0 AJAP1/PANP C-terminus MSC PF09402.5 CAM72765.1 - 0.065 11.9 0.4 0.091 11.4 0.2 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain SCF PF02404.10 CAM72765.1 - 0.068 12.3 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Stem cell factor DAG1 PF05454.6 CAM72765.1 - 0.072 12.2 0.0 0.072 12.2 0.0 1.6 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) NfeD PF01957.13 CAM72765.1 - 0.09 12.9 0.1 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding DAP10 PF07213.6 CAM72765.1 - 0.098 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 DAP10 membrane protein Tmemb_9 PF05434.6 CAM72765.1 - 0.12 12.1 0.9 0.28 10.9 0.6 1.6 1 0 0 1 1 1 0 TMEM9 BatD PF13584.1 CAM72765.1 - 0.14 10.7 0.4 0.25 9.8 0.2 1.4 1 1 1 2 2 2 0 Oxygen tolerance DUF4381 PF14316.1 CAM72765.1 - 0.14 12.2 8.6 0.22 11.5 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) MLANA PF14991.1 CAM72765.1 - 0.82 9.6 3.2 0.55 10.2 0.1 2.1 2 0 0 2 2 2 0 Protein melan-A WBP-1 PF11669.3 CAM72765.1 - 1.3 9.1 11.5 0.16 12.0 2.3 3.0 2 1 0 2 2 2 0 WW domain-binding protein 1 EF-hand_7 PF13499.1 CAM72766.1 - 1.8e-09 37.5 1.9 5.6e-09 36.0 0.2 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 CAM72766.1 - 1.2e-08 34.3 1.0 0.0009 18.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CAM72766.1 - 6.5e-08 31.3 0.1 0.0028 16.8 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 CAM72766.1 - 4.2e-06 26.1 0.1 0.0097 15.7 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 CAM72766.1 - 0.0039 16.4 0.2 0.014 14.7 0.0 2.0 2 0 0 2 2 2 1 EF hand PALP PF00291.20 CAM72769.2 - 1.7e-57 194.9 0.6 2e-57 194.7 0.4 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF2009 PF09418.5 CAM72770.1 - 2.8e-114 382.4 2.3 2.7e-113 379.1 1.6 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF2009) SRP54 PF00448.17 CAM72771.1 - 1.1e-53 181.6 0.1 2.4e-53 180.5 0.1 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 CAM72771.1 - 9.6e-19 67.8 0.3 2.6e-18 66.4 0.2 1.6 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.14 CAM72771.1 - 6.6e-06 26.1 0.1 1.4e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_22 PF13401.1 CAM72771.1 - 1e-05 25.7 0.1 5.1e-05 23.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CAM72771.1 - 2.1e-05 24.1 0.3 6.3e-05 22.6 0.2 1.8 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 CAM72771.1 - 0.0012 17.6 0.0 0.004 15.9 0.0 1.8 1 0 0 1 1 1 1 ArgK protein ETF PF01012.16 CAM72771.1 - 0.0012 18.5 0.6 0.076 12.7 0.1 2.6 2 0 0 2 2 2 1 Electron transfer flavoprotein domain APS_kinase PF01583.15 CAM72771.1 - 0.0016 18.1 0.1 0.0052 16.4 0.0 1.9 2 0 0 2 2 2 1 Adenylylsulphate kinase DAP3 PF10236.4 CAM72771.1 - 0.002 17.1 0.0 0.0036 16.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 Zeta_toxin PF06414.7 CAM72771.1 - 0.0054 15.8 0.0 0.032 13.3 0.0 2.3 2 1 0 2 2 2 1 Zeta toxin AAA_16 PF13191.1 CAM72771.1 - 0.0069 16.3 0.1 0.022 14.7 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.10 CAM72771.1 - 0.011 15.4 0.0 1.7 8.3 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_10 PF12846.2 CAM72771.1 - 0.012 15.0 0.0 0.071 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain CbiA PF01656.18 CAM72771.1 - 0.015 14.7 0.1 0.15 11.4 0.1 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.18 CAM72771.1 - 0.033 14.1 0.0 0.26 11.2 0.0 2.5 3 1 0 3 3 2 0 50S ribosome-binding GTPase cobW PF02492.14 CAM72771.1 - 0.045 13.2 0.1 0.11 11.9 0.0 1.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ArsA_ATPase PF02374.10 CAM72771.1 - 0.069 12.1 0.3 0.21 10.6 0.1 1.9 2 0 0 2 2 2 0 Anion-transporting ATPase ABC_tran PF00005.22 CAM72771.1 - 0.088 13.1 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.7 CAM72771.1 - 0.1 12.2 0.1 3.6 7.2 0.0 2.7 3 0 0 3 3 3 0 NACHT domain Thymidylate_kin PF02223.12 CAM72771.1 - 0.13 11.6 0.0 0.43 9.9 0.0 1.9 1 0 0 1 1 1 0 Thymidylate kinase SQS_PSY PF00494.14 CAM72772.1 - 1.2e-12 47.7 0.0 1.9e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF3846 PF12957.2 CAM72774.1 - 5.9e-16 57.9 0.0 4.5e-13 48.7 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3846) TPR_11 PF13414.1 CAM72774.1 - 8.4e-12 44.5 11.3 3.4e-08 33.0 0.3 2.8 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 CAM72774.1 - 0.001 18.5 12.9 0.0012 18.3 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 CAM72774.1 - 0.062 13.2 0.1 0.062 13.2 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 CAM72774.1 - 0.91 9.4 3.6 1.4 8.8 1.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 CAM72774.1 - 1.3 9.8 5.1 5.6 7.8 0.8 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF2150 PF09920.4 CAM72775.1 - 0.081 12.5 0.1 0.25 10.8 0.0 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) HALZ PF02183.13 CAM72777.1 - 0.034 13.8 2.4 0.081 12.6 0.1 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper DivIC PF04977.10 CAM72777.1 - 0.037 13.4 0.2 0.037 13.4 0.1 3.3 4 0 0 4 4 4 0 Septum formation initiator DUF972 PF06156.8 CAM72777.1 - 0.42 10.9 8.0 0.64 10.3 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF904 PF06005.7 CAM72777.1 - 1.3 9.4 14.2 0.5 10.6 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF904) DUF2870 PF11069.3 CAM72778.1 - 1.8e-28 98.4 0.0 4.3e-28 97.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) SMAP PF15477.1 CAM72779.1 - 2.6e-13 50.0 6.1 2.6e-13 50.0 4.2 2.0 2 1 0 2 2 2 1 Small acidic protein family DUF4404 PF14357.1 CAM72779.1 - 0.14 12.5 2.4 0.45 10.9 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Transket_pyr PF02779.19 CAM72780.1 - 3.4e-56 189.5 0.0 2.2e-55 186.9 0.0 2.1 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 CAM72780.1 - 2.1e-49 167.8 0.0 3.5e-49 167.1 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component NIPSNAP PF07978.8 CAM72781.1 - 1.8e-14 53.5 0.0 3e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 NIPSNAP Glyco_transf_25 PF01755.12 CAM72782.1 - 6.6e-11 42.2 0.0 2.1e-10 40.5 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Snf7 PF03357.16 CAM72783.1 - 1.3e-26 92.9 31.1 1.3e-26 92.9 21.5 1.9 1 1 1 2 2 2 1 Snf7 Peptidase_C65 PF10275.4 CAM72783.1 - 7.6 5.8 9.6 4 6.7 5.0 1.7 1 1 1 2 2 2 0 Peptidase C65 Otubain CRAL_TRIO PF00650.15 CAM72784.2 - 4.3e-28 97.7 0.0 6.2e-28 97.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 CAM72784.2 - 0.012 15.4 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Vps26 PF03643.10 CAM72785.1 - 5.1e-53 179.6 0.6 6.2e-53 179.3 0.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 CAM72785.1 - 1.2e-05 25.1 2.7 0.035 13.9 0.0 3.1 3 1 1 4 4 4 2 Arrestin (or S-antigen), N-terminal domain adh_short PF00106.20 CAM72786.1 - 2.1e-23 83.0 0.3 3.7e-23 82.2 0.2 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CAM72786.1 - 8.2e-11 41.8 0.8 2.6e-10 40.2 0.6 1.7 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CAM72786.1 - 0.00026 20.8 0.0 0.00037 20.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_31 PF13847.1 CAM72786.1 - 0.00032 20.3 0.0 0.00066 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CAM72786.1 - 0.019 14.0 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Polysacc_synt_2 PF02719.10 CAM72786.1 - 0.036 12.9 0.0 0.054 12.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 CAM72786.1 - 0.092 12.3 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ribosomal_L29e PF01779.12 CAM72787.1 - 5.5e-17 61.3 7.0 5.5e-17 61.3 4.8 1.8 2 0 0 2 2 2 1 Ribosomal L29e protein family Tymo_45kd_70kd PF03251.8 CAM72787.1 - 0.0016 17.2 0.1 0.0016 17.1 0.1 1.1 1 0 0 1 1 1 1 Tymovirus 45/70Kd protein HTH_Tnp_Mu_2 PF09039.6 CAM72787.1 - 0.097 12.4 0.1 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Mu DNA binding, I gamma subdomain Ribosomal_L29e PF01779.12 CAM72788.1 - 2.3e-17 62.5 7.9 2.3e-17 62.5 5.5 1.8 2 0 0 2 2 2 1 Ribosomal L29e protein family Tymo_45kd_70kd PF03251.8 CAM72788.1 - 0.00028 19.6 0.1 0.00031 19.5 0.1 1.1 1 0 0 1 1 1 1 Tymovirus 45/70Kd protein HTH_Tnp_Mu_2 PF09039.6 CAM72788.1 - 0.093 12.4 0.1 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Mu DNA binding, I gamma subdomain Bromodomain PF00439.20 CAM72791.1 - 6.1e-14 51.7 0.0 1.4e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Bromodomain YtzH PF14165.1 CAM72791.1 - 0.02 15.1 0.3 0.06 13.5 0.0 2.0 2 1 1 3 3 3 0 YtzH-like protein DUF3595 PF12166.3 CAM72793.1 - 1.3e-119 399.8 0.0 1.8e-119 399.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3595) DUF3134 PF11332.3 CAM72793.1 - 0.34 11.0 0.0 0.87 9.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3134) VCX_VCY PF15231.1 CAM72794.1 - 0.13 12.6 2.4 0.15 12.4 1.0 1.6 1 1 0 1 1 1 0 Variable charge X/Y family Actin PF00022.14 CAM72796.1 - 1.1e-98 330.3 0.0 1.2e-98 330.1 0.0 1.0 1 0 0 1 1 1 1 Actin Macro PF01661.16 CAM72798.1 - 3.6e-05 23.6 0.0 5.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Macro domain ECH PF00378.15 CAM72799.1 - 4.3e-12 45.6 0.1 8e-08 31.6 0.0 2.4 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 CAM72799.1 - 5.9e-11 42.5 0.1 1.2e-07 31.8 0.0 3.7 3 0 0 3 3 3 2 2-enoyl-CoA Hydratase C-terminal region UMP1 PF05348.6 CAM72799.1 - 0.11 12.5 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Proteasome maturation factor UMP1 Ribosomal_L22e PF01776.12 CAM72800.1 - 1.3e-39 134.6 3.0 1.6e-39 134.3 2.1 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF1712 PF08217.6 CAM72802.1 - 0.00011 20.5 0.0 0.00015 20.1 0.0 1.1 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) Ribosomal_S24e PF01282.14 CAM72805.1 - 8.5e-28 95.9 0.0 1.4e-27 95.2 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S24e Ribosomal_S24e PF01282.14 CAM72806.1 - 8.5e-28 95.9 0.0 1.4e-27 95.2 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S24e Motile_Sperm PF00635.21 CAM72807.1 - 3.2e-11 42.8 0.0 0.07 12.7 0.0 6.4 6 0 0 6 6 6 4 MSP (Major sperm protein) domain ABC2_membrane PF01061.19 CAM72808.1 - 2.7e-33 114.9 17.0 2.7e-33 114.9 11.8 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 CAM72808.1 - 7.5e-23 81.3 0.0 1.2e-22 80.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CAM72808.1 - 6.6e-08 32.8 0.1 0.002 18.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CAM72808.1 - 0.00014 21.9 0.8 0.0011 19.0 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 CAM72808.1 - 0.00075 18.7 0.1 0.0013 17.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CAM72808.1 - 0.0013 18.9 0.1 0.0074 16.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CAM72808.1 - 0.0033 16.9 0.1 0.0074 15.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 CAM72808.1 - 0.009 15.4 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CAM72808.1 - 0.01 15.5 0.1 0.063 13.0 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain AAA_30 PF13604.1 CAM72808.1 - 0.014 14.9 1.0 0.1 12.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 CAM72808.1 - 0.022 14.2 0.0 0.047 13.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.1 CAM72808.1 - 0.025 15.3 0.0 0.052 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 CAM72808.1 - 0.028 14.4 0.1 0.064 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 CAM72808.1 - 0.034 13.3 0.0 0.075 12.2 0.0 1.5 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain T2SE PF00437.15 CAM72808.1 - 0.036 12.9 0.0 0.052 12.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein ArgK PF03308.11 CAM72808.1 - 0.09 11.5 0.2 0.17 10.6 0.1 1.3 1 0 0 1 1 1 0 ArgK protein AAA_18 PF13238.1 CAM72808.1 - 0.091 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 CAM72808.1 - 0.13 11.9 0.1 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 CAM72808.1 - 0.14 11.8 0.6 0.3 10.7 0.1 1.8 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.1 CAM72808.1 - 0.35 11.1 0.0 0.57 10.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain MCM PF00493.18 CAM72809.2 - 1.9e-06 26.9 0.0 3.1e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family AAA_16 PF13191.1 CAM72809.2 - 0.0018 18.2 1.4 0.0037 17.2 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain Lar_restr_allev PF14354.1 CAM72809.2 - 0.042 14.1 0.2 0.14 12.4 0.1 1.9 1 0 0 1 1 1 0 Restriction alleviation protein Lar AAA_22 PF13401.1 CAM72809.2 - 0.1 12.7 0.1 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 CAM72809.2 - 0.18 11.9 0.2 0.38 10.9 0.1 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PHF5 PF03660.9 CAM72811.1 - 9.9e-36 122.0 10.1 1.1e-35 121.8 7.0 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 CAM72811.1 - 0.29 10.9 8.7 0.065 13.0 2.9 2.1 1 1 1 2 2 2 0 Double zinc ribbon TF_Zn_Ribbon PF08271.7 CAM72811.1 - 0.98 8.7 8.9 1.9 7.8 0.5 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding FYVE_2 PF02318.11 CAM72811.1 - 1.7 8.5 10.2 0.56 10.1 5.2 1.6 2 0 0 2 2 2 0 FYVE-type zinc finger zf-C3HC4_2 PF13923.1 CAM72811.1 - 2 8.4 9.5 0.53 10.3 2.7 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CAM72812.1 - 4.9e-13 48.6 6.7 4.9e-13 48.6 4.6 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 CAM72812.1 - 2.5e-08 33.7 6.5 2.5e-08 33.7 4.5 2.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CAM72812.1 - 5.8e-08 32.7 3.4 1.4e-07 31.5 2.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CAM72812.1 - 2.4e-07 30.2 4.3 2.4e-07 30.2 3.0 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CAM72812.1 - 5.1e-07 29.2 3.6 5.1e-07 29.2 2.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAM72812.1 - 6.3e-07 29.0 4.6 1.8e-06 27.5 3.2 1.8 1 0 0 1 1 1 1 zinc-RING finger domain PHD PF00628.24 CAM72812.1 - 0.005 16.4 8.7 0.0073 15.9 3.5 2.4 2 0 0 2 2 2 1 PHD-finger zf-Apc11 PF12861.2 CAM72812.1 - 0.061 13.1 4.7 0.21 11.4 3.2 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 CAM72812.1 - 0.24 11.3 4.6 0.89 9.5 3.2 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 CAM72812.1 - 0.26 10.8 4.8 0.72 9.4 3.3 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 CAM72812.1 - 0.29 10.8 2.8 0.7 9.6 2.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_1 PF14446.1 CAM72812.1 - 0.57 9.9 7.8 2.9 7.7 5.4 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 PI3_PI4_kinase PF00454.22 CAM72813.1 - 1.2e-22 80.5 0.0 2.9e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase NUC194 PF08163.7 CAM72813.1 - 2.7e-09 36.4 0.0 1.4e-05 24.1 0.0 2.4 2 0 0 2 2 2 2 NUC194 domain FATC PF02260.15 CAM72813.1 - 2.9e-05 23.4 0.7 7.4e-05 22.0 0.0 2.2 2 0 0 2 2 2 1 FATC domain BpuJI_N PF11564.3 CAM72813.1 - 3 6.7 0.0 5.1 5.9 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease BpuJI - N terminal ATP-grasp_2 PF08442.5 CAM72814.1 - 4.1e-65 218.9 4.0 6.1e-65 218.3 2.8 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 CAM72814.1 - 1e-21 77.1 1.2 1e-21 77.1 0.8 2.4 3 0 0 3 3 3 1 CoA-ligase 5TM-5TMR_LYT PF07694.7 CAM72815.1 - 0.048 13.0 2.7 0.34 10.2 2.7 1.7 1 1 1 2 2 2 0 5TMR of 5TMR-LYT SID-1_RNA_chan PF13965.1 CAM72815.1 - 0.075 11.1 0.5 0.066 11.3 0.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 YlaH PF14036.1 CAM72816.1 - 0.018 15.1 1.3 0.018 15.1 0.9 1.8 2 0 0 2 2 2 0 YlaH-like protein DUF1430 PF07242.6 CAM72816.1 - 0.13 12.3 1.0 0.24 11.4 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1430) DUF2681 PF10883.3 CAM72816.1 - 8.5 6.6 8.1 0.52 10.5 1.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Bromodomain PF00439.20 CAM72817.1 - 2.9e-22 78.3 0.0 4.6e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 Bromodomain TGF_beta_GS PF08515.7 CAM72817.1 - 6.9 6.0 6.6 16 4.9 4.6 1.6 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif GTP1_OBG PF01018.17 CAM72818.1 - 6e-35 120.2 5.3 8.6e-35 119.6 3.7 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.18 CAM72818.1 - 7e-17 61.4 0.0 1.1e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CAM72818.1 - 4.5e-06 26.0 0.0 0.00013 21.2 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B DSHCT PF08148.7 CAM72819.1 - 8.9e-53 178.1 0.3 2.3e-52 176.8 0.2 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.1 CAM72819.1 - 1.1e-51 175.5 0.1 5.1e-51 173.3 0.1 1.9 2 0 0 2 2 2 1 rRNA-processing arch domain DEAD PF00270.24 CAM72819.1 - 4e-25 88.2 0.2 3.5e-24 85.2 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM72819.1 - 6.8e-07 29.0 0.0 2.1e-06 27.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 CAM72819.1 - 0.00071 19.2 0.0 0.0025 17.5 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 CAM72819.1 - 0.00081 19.2 0.0 0.0038 17.0 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.11 CAM72819.1 - 0.00098 18.4 0.1 0.0021 17.3 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein Zot PF05707.7 CAM72819.1 - 0.0011 18.5 0.0 0.0038 16.7 0.0 1.9 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) T2SE PF00437.15 CAM72819.1 - 0.0096 14.8 0.1 0.047 12.5 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein FlxA PF14282.1 CAM72819.1 - 0.032 14.1 2.6 0.067 13.1 1.8 1.5 1 0 0 1 1 1 0 FlxA-like protein Arch_ATPase PF01637.13 CAM72819.1 - 0.043 13.5 0.4 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase RMMBL PF07521.7 CAM72819.1 - 0.076 12.8 0.0 2.2 8.1 0.0 2.8 2 0 0 2 2 2 0 RNA-metabolising metallo-beta-lactamase GSHPx PF00255.14 CAM72820.1 - 2.3e-27 94.4 0.1 2.8e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 CAM72820.1 - 0.0019 17.8 0.0 0.0026 17.4 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CAM72820.1 - 0.0049 16.4 0.0 0.007 15.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin RNase_PH PF01138.16 CAM72821.1 - 2.9e-28 98.7 0.3 4e-28 98.3 0.2 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CAM72821.1 - 1.6e-05 24.6 0.0 3.6e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF1623 PF07785.6 CAM72821.1 - 0.038 13.9 0.7 0.069 13.1 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1623) Adap_comp_sub PF00928.16 CAM72822.1 - 3e-56 190.4 0.0 3.8e-56 190.1 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CAM72822.1 - 0.00019 21.1 0.5 0.00031 20.4 0.3 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RRM_1 PF00076.17 CAM72823.1 - 1.5e-08 34.1 0.0 2.2e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAM72823.1 - 5.6e-07 29.3 0.0 8.4e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAM72823.1 - 0.0019 18.1 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Phage_Gp23 PF10669.4 CAM72823.1 - 0.074 13.1 1.6 0.12 12.4 1.1 1.3 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Peroxin-22 PF12827.2 CAM72824.1 - 0.07 12.8 0.0 0.082 12.6 0.0 1.2 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family Cullin PF00888.17 CAM72825.1 - 3e-46 158.1 0.2 3.9e-46 157.7 0.1 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CAM72825.1 - 8.6e-15 54.3 0.0 7.5e-14 51.3 0.0 2.4 2 0 0 2 2 2 1 Cullin protein neddylation domain Mating_N PF12731.2 CAM72825.1 - 0.11 12.3 0.8 5.5 6.9 0.1 2.8 2 0 0 2 2 2 0 Mating-type protein beta 1 Fibrillarin PF01269.12 CAM72826.1 - 1.2e-104 348.2 0.0 1.4e-104 348.0 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 CAM72826.1 - 0.00047 19.7 0.0 0.00071 19.1 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 CAM72826.1 - 0.019 14.5 0.1 0.034 13.6 0.1 1.3 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) BPL_LplA_LipB PF03099.14 CAM72827.1 - 3.4e-07 30.3 0.0 8e-07 29.1 0.0 1.6 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family vATP-synt_E PF01991.13 CAM72829.1 - 6.2e-41 139.8 8.5 7.1e-41 139.6 5.9 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit GTP_cyclohydro2 PF00925.15 CAM72829.1 - 0.07 12.3 1.6 1.8 7.7 0.1 2.4 1 1 1 2 2 2 0 GTP cyclohydrolase II Acyl-CoA_dh_N PF02771.11 CAM72829.1 - 0.3 11.6 2.5 0.62 10.6 0.9 2.0 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain DUF932 PF06067.6 CAM72829.1 - 2.1 7.6 9.9 1.4 8.2 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF932) EF-hand_8 PF13833.1 CAM72831.1 - 6.9e-06 25.5 0.1 0.00027 20.4 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CAM72831.1 - 0.0087 15.2 0.2 2.6 7.5 0.0 3.3 4 0 0 4 4 4 1 EF hand EF-hand_7 PF13499.1 CAM72831.1 - 0.031 14.4 0.1 0.48 10.5 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.1 CAM72831.1 - 0.09 12.7 0.1 25 5.0 0.0 3.7 4 0 0 4 4 4 0 EF-hand domain Pro_isomerase PF00160.16 CAM72832.1 - 1.5e-34 119.4 0.0 1.8e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ArfGap PF01412.13 CAM72834.1 - 3.9e-24 84.6 0.0 8.2e-24 83.6 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TBCC PF07986.7 CAM72835.1 - 6.1e-25 86.9 0.7 1.2e-24 86.0 0.5 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C CDC37_N PF03234.9 CAM72835.1 - 0.52 10.6 6.0 0.87 9.8 4.2 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding cobW PF02492.14 CAM72836.1 - 2.4e-45 154.1 0.2 3.6e-45 153.5 0.2 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 CAM72836.1 - 0.0034 17.0 0.5 0.012 15.3 0.2 2.1 2 1 0 2 2 2 1 Part of AAA domain AAA_29 PF13555.1 CAM72836.1 - 0.01 15.3 0.0 0.095 12.2 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 CAM72836.1 - 0.018 14.5 0.3 0.04 13.4 0.2 1.5 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 CAM72836.1 - 0.02 15.1 0.2 0.13 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CAM72836.1 - 0.028 14.2 0.1 0.07 13.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 CAM72836.1 - 0.029 14.5 0.1 0.067 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain adh_short PF00106.20 CAM72836.1 - 0.053 13.4 0.7 5.4 6.9 0.3 2.2 1 1 0 2 2 2 0 short chain dehydrogenase MobB PF03205.9 CAM72836.1 - 0.093 12.4 0.1 0.25 11.0 0.1 1.8 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 CAM72836.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Guanylate_cyc PF00211.15 CAM72837.1 - 8.8e-38 129.5 0.0 1.5e-37 128.7 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF1935 PF09149.5 CAM72837.1 - 8.2e-29 99.6 0.0 1.8e-28 98.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) zf-CCHC PF00098.18 CAM72838.1 - 1.7e-18 65.5 81.3 0.00057 19.6 0.8 10.2 10 0 0 10 10 10 8 Zinc knuckle zf-CCHC_2 PF13696.1 CAM72838.1 - 0.00044 19.6 0.8 0.00044 19.6 0.6 7.5 4 2 3 7 7 7 4 Zinc knuckle NYN PF01936.13 CAM72838.1 - 0.09 13.0 0.0 0.26 11.5 0.0 1.7 2 0 0 2 2 2 0 NYN domain Topoisom_bac PF01131.15 CAM72839.1 - 7.8e-96 321.3 0.0 2.3e-95 319.7 0.0 1.6 2 0 0 2 2 2 1 DNA topoisomerase Toprim PF01751.17 CAM72839.1 - 2.9e-15 56.0 0.0 5.9e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Toprim domain zf-GRF PF06839.7 CAM72839.1 - 1.5e-07 31.2 1.0 1.5e-07 31.2 0.7 2.7 2 0 0 2 2 2 1 GRF zinc finger zf-C4_Topoisom PF01396.14 CAM72839.1 - 3.5e-06 26.3 0.1 3.5e-06 26.3 0.0 4.5 5 0 0 5 5 5 1 Topoisomerase DNA binding C4 zinc finger Lar_restr_allev PF14354.1 CAM72839.1 - 0.00045 20.4 7.0 0.28 11.5 0.2 4.0 3 0 0 3 3 3 2 Restriction alleviation protein Lar Cys_rich_CPCC PF14206.1 CAM72839.1 - 0.068 12.7 0.9 0.31 10.6 0.3 2.3 2 0 0 2 2 2 0 Cysteine-rich CPCC HypA PF01155.14 CAM72839.1 - 0.19 11.4 11.4 0.33 10.6 0.1 3.9 3 1 0 3 3 3 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_5 PF13719.1 CAM72839.1 - 0.38 10.3 0.0 0.38 10.3 0.0 4.1 5 0 0 5 5 5 0 zinc-ribbon domain DUF3133 PF11331.3 CAM72839.1 - 0.66 9.5 7.8 3.5 7.2 0.1 4.2 4 1 0 4 4 4 0 Protein of unknown function (DUF3133) Auto_anti-p27 PF06677.7 CAM72839.1 - 8.4 6.2 8.0 48 3.8 1.3 3.8 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) 14-3-3 PF00244.15 CAM72840.1 - 1.5e-91 305.6 2.0 1.7e-91 305.5 1.4 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 CAM72840.1 - 0.012 15.5 4.6 0.04 13.8 0.6 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 CAM72840.1 - 7.7 6.7 6.6 5.4 7.1 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat CENP-F_leu_zip PF10473.4 CAM72841.1 - 0.013 15.3 4.6 0.013 15.3 3.2 7.1 1 1 4 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Matrilin_ccoil PF10393.4 CAM72841.1 - 0.014 14.7 0.1 0.014 14.7 0.1 4.1 5 0 0 5 5 5 0 Trimeric coiled-coil oligomerisation domain of matrilin Reo_sigmaC PF04582.7 CAM72841.1 - 1.7 7.7 22.1 0.1 11.7 2.1 3.3 1 1 3 4 4 4 0 Reovirus sigma C capsid protein GMC_oxred_N PF00732.14 CAM72842.1 - 2.8e-48 164.5 0.0 5.7e-48 163.5 0.0 1.4 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CAM72842.1 - 6.3e-20 71.9 0.0 1.1e-19 71.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 CAM72842.1 - 1.5e-07 30.6 4.5 0.00013 20.9 0.5 2.9 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.19 CAM72842.1 - 1.8e-07 30.3 6.1 1.8e-05 23.8 2.8 3.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CAM72842.1 - 1.8e-05 24.7 0.0 0.00013 21.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CAM72842.1 - 0.0015 18.4 0.9 0.0062 16.5 0.6 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 CAM72842.1 - 0.0056 15.5 0.7 0.17 10.7 1.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 CAM72842.1 - 0.0061 16.6 0.0 0.2 11.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CAM72842.1 - 0.0081 15.1 1.0 0.01 14.7 0.2 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.9 CAM72842.1 - 0.011 14.2 0.7 0.035 12.5 0.5 1.7 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.2 CAM72842.1 - 0.035 13.1 2.8 0.39 9.7 1.3 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase EF1_GNE PF00736.14 CAM72843.1 - 8.5e-30 102.2 1.7 1.4e-29 101.6 1.2 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain TSP9 PF11493.3 CAM72843.1 - 4.7 7.8 8.8 24 5.5 6.1 2.0 1 1 0 1 1 1 0 Thylakoid soluble phosphoprotein TSP9 Chorein_N PF12624.2 CAM72844.2 - 2.6e-25 88.2 0.1 1e-11 44.3 0.0 2.5 2 0 0 2 2 2 2 N-terminal region of Chorein, a TM vesicle-mediated sorter Sugarporin_N PF11471.3 CAM72846.1 - 6.2 6.5 6.7 0.74 9.5 0.2 2.4 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Kelch_1 PF01344.20 CAM72847.1 - 1.6e-17 62.7 0.5 3.7e-07 29.5 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 CAM72847.1 - 1.7e-15 56.4 2.5 4.1e-06 26.7 0.0 5.7 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 CAM72847.1 - 3.8e-15 55.3 1.0 3.2e-06 26.7 0.0 5.8 5 1 1 6 6 6 2 Galactose oxidase, central domain Kelch_3 PF13415.1 CAM72847.1 - 7.5e-15 54.6 0.3 3.1e-06 27.1 0.0 4.6 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CAM72847.1 - 4.8e-11 41.9 0.5 1.4e-05 24.6 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 CAM72847.1 - 1.5e-08 34.4 6.1 0.0016 18.3 0.0 4.2 4 0 0 4 4 4 2 Kelch motif TetR_C PF02909.12 CAM72850.1 - 0.014 15.0 1.7 1.2 8.8 0.0 3.0 3 0 0 3 3 3 0 Tetracyclin repressor, C-terminal all-alpha domain DUF4515 PF14988.1 CAM72851.1 - 0.0073 15.9 1.4 0.011 15.4 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4515) Fib_alpha PF08702.5 CAM72851.1 - 0.011 15.8 0.6 0.014 15.4 0.4 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4392 PF14336.1 CAM72851.1 - 0.036 12.8 0.2 0.05 12.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) TBPIP PF07106.8 CAM72851.1 - 0.046 13.2 1.9 0.065 12.7 1.3 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) PilJ PF13675.1 CAM72851.1 - 0.047 14.0 0.5 0.07 13.4 0.3 1.3 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4363 PF14276.1 CAM72851.1 - 0.067 12.8 0.5 0.13 12.0 0.3 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4363) Peptidase_M19 PF01244.16 CAM72851.1 - 0.077 11.9 0.1 0.091 11.6 0.1 1.3 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) Hormone_1 PF00103.15 CAM72851.1 - 0.089 12.1 1.2 0.15 11.4 0.8 1.5 1 1 0 1 1 1 0 Somatotropin hormone family Spectrin PF00435.16 CAM72851.1 - 0.11 12.7 3.6 0.16 12.2 0.3 2.3 1 1 1 2 2 2 0 Spectrin repeat ABM PF03992.11 CAM72851.1 - 0.13 12.3 0.2 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase PIG-P PF08510.7 CAM72851.1 - 0.13 11.8 0.2 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 PIG-P AATF-Che1 PF13339.1 CAM72851.1 - 0.16 12.1 3.4 1.9 8.6 1.1 2.1 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Tup_N PF08581.5 CAM72851.1 - 0.53 10.5 3.5 0.97 9.6 2.4 1.6 1 1 0 1 1 1 0 Tup N-terminal Snf7 PF03357.16 CAM72851.1 - 2.8 7.3 7.5 0.93 8.8 1.2 2.0 1 1 1 2 2 2 0 Snf7 Pkinase PF00069.20 CAM72852.1 - 1.7e-54 184.7 0.0 2.5e-54 184.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM72852.1 - 3.3e-35 121.4 0.0 5.4e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM72852.1 - 2e-06 26.9 0.0 3.9e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 Kinase-like PH PF00169.24 CAM72852.1 - 6.1e-05 23.1 0.1 0.00013 22.1 0.1 1.6 1 1 0 1 1 1 1 PH domain PH_9 PF15410.1 CAM72852.1 - 0.029 14.5 0.2 0.11 12.6 0.1 2.0 2 1 0 2 2 2 0 Pleckstrin homology domain PH_4 PF15404.1 CAM72852.1 - 0.034 13.6 0.1 0.087 12.3 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain PH_2 PF08458.5 CAM72852.1 - 0.078 12.9 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Plant pleckstrin homology-like region PH_11 PF15413.1 CAM72852.1 - 0.095 12.9 0.1 0.26 11.5 0.0 1.8 1 1 0 1 1 1 0 Pleckstrin homology domain Pkinase PF00069.20 CAM72853.1 - 7.6e-54 182.5 0.0 1e-53 182.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM72853.1 - 1.4e-34 119.3 0.0 2.2e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM72853.1 - 6.6e-07 28.5 0.0 1e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PH PF00169.24 CAM72853.1 - 0.00016 21.8 0.0 0.0012 18.9 0.0 2.3 1 1 0 1 1 1 1 PH domain ELMO_CED12 PF04727.8 CAM72854.1 - 1.1e-40 138.9 0.0 1.5e-40 138.4 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family zf-B_box PF00643.19 CAM72855.1 - 9.1e-09 35.0 7.1 9.1e-09 35.0 5.0 3.6 5 0 0 5 5 5 2 B-box zinc finger Baculo_PEP_C PF04513.7 CAM72855.1 - 0.027 14.2 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus LRR_4 PF12799.2 CAM72856.1 - 4.3e-23 80.4 3.1 1.5e-05 24.4 0.0 5.7 5 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM72856.1 - 7.8e-19 67.1 7.3 3.7e-08 32.9 0.2 4.2 4 0 0 4 4 4 3 Leucine rich repeat LRR_6 PF13516.1 CAM72856.1 - 1.6e-09 36.8 5.2 8.1 6.8 0.1 8.3 9 0 0 9 9 9 3 Leucine Rich repeat LRR_1 PF00560.28 CAM72856.1 - 1.1e-08 33.8 15.5 0.6 10.3 0.3 8.8 8 1 0 8 8 8 1 Leucine Rich Repeat LRR_7 PF13504.1 CAM72856.1 - 3.1e-06 26.4 20.2 3.9 8.1 0.1 8.5 8 1 0 8 8 8 3 Leucine rich repeat LRR_9 PF14580.1 CAM72856.1 - 0.00088 18.8 3.1 0.043 13.3 0.4 2.4 1 1 2 3 3 3 3 Leucine-rich repeat LRR_5 PF13306.1 CAM72856.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.5 1 1 0 1 1 1 0 Leucine rich repeats (6 copies) DUF743 PF05332.6 CAM72857.2 - 0.012 15.5 0.5 0.056 13.3 0.3 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF743) DUF948 PF06103.6 CAM72857.2 - 5.7 6.8 6.1 6.2 6.7 0.0 3.4 3 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Rnk_N PF14760.1 CAM72858.1 - 0.025 14.6 1.7 0.32 11.0 0.1 3.1 3 0 0 3 3 3 0 Rnk N-terminus STAG PF08514.6 CAM72859.1 - 2.3e-17 62.7 2.6 2.6e-17 62.6 0.3 2.3 2 0 0 2 2 2 1 STAG domain DUF2435 PF10363.4 CAM72859.1 - 0.044 13.6 3.6 7.2 6.5 0.0 4.5 4 1 1 5 5 5 0 Protein of unknown function (DUF2435) GlutR_dimer PF00745.15 CAM72859.1 - 0.49 10.3 5.2 1.5 8.8 0.4 3.5 2 1 1 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain Proteasome PF00227.21 CAM72861.1 - 7.6e-57 191.6 0.0 9.4e-57 191.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CAM72861.1 - 9.2e-14 50.4 0.0 3.2e-13 48.7 0.0 2.0 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature zf-CCHC PF00098.18 CAM72862.1 - 1.4e-42 141.6 34.7 1.3e-09 37.4 1.3 5.1 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.1 CAM72862.1 - 3.9e-14 52.0 29.6 0.00041 19.9 0.6 5.0 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_3 PF13917.1 CAM72862.1 - 2.6e-13 49.4 25.3 0.0064 16.1 0.5 5.0 1 1 4 5 5 5 5 Zinc knuckle zf-CCHC_2 PF13696.1 CAM72862.1 - 1.1e-07 31.2 19.8 0.0052 16.2 0.1 4.9 2 2 3 5 5 5 3 Zinc knuckle zf-CCHC_6 PF15288.1 CAM72862.1 - 3.4e-05 23.4 28.3 0.081 12.6 0.5 5.1 2 2 3 5 5 5 3 Zinc knuckle Dermcidin PF15291.1 CAM72862.1 - 0.093 12.9 0.5 4.5 7.5 0.2 2.2 1 1 1 2 2 2 0 Dermcidin, antibiotic peptide DUF2387 PF09526.5 CAM72862.1 - 1.1 9.2 18.8 2.7 7.9 2.3 3.4 1 1 3 4 4 4 0 Probable metal-binding protein (DUF2387) TNFR_c6 PF00020.13 CAM72862.1 - 1.8 8.6 32.1 7 6.7 1.0 5.0 2 2 3 5 5 5 0 TNFR/NGFR cysteine-rich region RMF PF04957.7 CAM72862.1 - 2 8.1 7.9 17 5.2 0.1 3.4 2 2 1 3 3 3 0 Ribosome modulation factor zf-C2HC_2 PF13913.1 CAM72862.1 - 5.5 6.7 23.3 5.9 6.6 0.1 5.5 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zf-CCHC PF00098.18 CAM72863.1 - 1.7e-42 141.3 36.1 1.3e-09 37.4 1.3 5.1 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.1 CAM72863.1 - 7.1e-15 54.4 28.2 0.00041 19.9 0.6 5.0 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_3 PF13917.1 CAM72863.1 - 1.4e-13 50.3 25.4 0.0076 15.9 0.6 5.0 1 1 4 5 5 5 5 Zinc knuckle zf-CCHC_2 PF13696.1 CAM72863.1 - 4.7e-07 29.1 20.3 0.007 15.8 0.2 4.9 2 2 3 5 5 5 3 Zinc knuckle zf-CCHC_6 PF15288.1 CAM72863.1 - 1.7e-05 24.4 29.9 0.023 14.3 1.2 5.1 2 2 3 5 5 5 3 Zinc knuckle Toxin_44 PF15523.1 CAM72863.1 - 0.6 10.0 0.1 0.6 10.0 0.0 3.6 1 1 2 3 3 3 0 Putative toxin 44 RMF PF04957.7 CAM72863.1 - 1.5 8.5 7.9 23 4.7 0.1 3.4 2 2 1 3 3 3 0 Ribosome modulation factor DUF2387 PF09526.5 CAM72863.1 - 2 8.4 19.6 2.1 8.3 1.9 3.4 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) TNFR_c6 PF00020.13 CAM72863.1 - 2.3 8.3 32.4 7.2 6.7 1.0 5.0 2 2 3 5 5 5 0 TNFR/NGFR cysteine-rich region zf-HYPF PF07503.7 CAM72863.1 - 4.9 6.6 18.9 24 4.4 0.1 5.5 5 1 0 5 5 5 0 HypF finger Clathrin PF00637.15 CAM72864.1 - 4.3e-163 535.3 41.2 2.3e-27 95.3 0.1 8.9 9 0 0 9 9 9 8 Region in Clathrin and VPS Clathrin_H_link PF13838.1 CAM72864.1 - 3.8e-22 77.9 0.1 2.8e-21 75.1 0.0 2.7 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.15 CAM72864.1 - 1.3e-13 50.2 0.5 0.6 10.5 0.0 6.6 7 0 0 7 7 7 5 Clathrin propeller repeat Clathrin-link PF09268.5 CAM72864.1 - 4.6e-06 25.5 1.6 5.5e-06 25.2 0.0 2.1 2 0 0 2 2 2 1 Clathrin, heavy-chain linker TPR_1 PF00515.23 CAM72864.1 - 0.014 15.0 0.5 7.2 6.4 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 CAM72864.1 - 0.025 14.3 4.7 20 5.2 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat ATP13 PF12921.2 CAM72864.1 - 0.043 13.1 0.4 0.29 10.4 0.0 2.7 3 0 0 3 3 3 0 Mitochondrial ATPase expression Egg_lysin PF01303.12 CAM72864.1 - 0.13 12.2 5.3 1.1 9.3 0.4 3.6 3 0 0 3 3 3 0 Egg lysin (Sperm-lysin) zf-CCHC PF00098.18 CAM72865.1 - 2.3e-39 131.4 50.2 1.4e-07 31.0 1.8 6.1 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_3 PF13917.1 CAM72865.1 - 4.5e-08 32.6 33.4 0.0085 15.8 0.7 5.1 2 1 3 5 5 5 4 Zinc knuckle zf-CCHC_2 PF13696.1 CAM72865.1 - 1.4e-07 30.8 35.6 0.00064 19.1 1.8 5.8 4 1 2 6 6 6 4 Zinc knuckle zf-CCHC_4 PF14392.1 CAM72865.1 - 6.9e-07 28.8 38.0 0.097 12.3 0.4 6.0 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_5 PF14787.1 CAM72865.1 - 5.4e-05 22.5 36.5 0.0021 17.5 0.9 5.3 4 1 1 5 5 5 4 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.18 CAM72866.1 - 2e-75 245.3 80.2 3.7e-09 36.0 1.0 9.2 9 0 0 9 9 9 9 Zinc knuckle zf-CCHC_3 PF13917.1 CAM72866.1 - 6.9e-26 89.7 51.2 0.00027 20.5 0.6 9.1 4 2 5 9 9 9 9 Zinc knuckle zf-CCHC_2 PF13696.1 CAM72866.1 - 1e-12 47.2 46.6 0.082 12.4 0.1 9.2 9 0 0 9 9 9 9 Zinc knuckle zf-CCHC_4 PF14392.1 CAM72866.1 - 1.3e-10 40.7 64.3 0.45 10.2 0.6 9.1 9 0 0 9 9 9 9 Zinc knuckle eIF3g PF12353.3 CAM72866.1 - 0.0054 16.6 1.2 0.0054 16.6 0.8 8.6 5 2 4 9 9 9 4 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_6 PF15288.1 CAM72866.1 - 0.052 13.2 68.3 0.18 11.4 0.7 9.2 9 0 0 9 9 9 0 Zinc knuckle Proteasome PF00227.21 CAM72867.1 - 1.3e-49 168.0 0.2 1.7e-49 167.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit S4 PF01479.20 CAM72868.1 - 3e-07 29.7 0.0 1.3e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 S4 domain PseudoU_synth_2 PF00849.17 CAM72868.1 - 1.5e-06 28.1 0.0 2.7e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase SAGA-Tad1 PF12767.2 CAM72868.1 - 0.63 9.6 4.6 1.3 8.5 3.2 1.5 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF2419 PF10343.4 CAM72869.1 - 1.1e-14 54.4 0.0 1.3e-13 50.8 0.0 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2419) Peptidase_M76 PF09768.4 CAM72871.1 - 2.7e-53 179.9 0.2 2.1e-52 177.0 0.2 1.9 1 1 0 1 1 1 1 Peptidase M76 family HTH_30 PF13556.1 CAM72871.1 - 0.0048 16.4 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain GPI2 PF06432.6 CAM72873.1 - 1.5e-78 263.9 13.3 1.8e-78 263.7 9.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF1634 PF07843.6 CAM72873.1 - 0.099 12.2 0.3 0.099 12.2 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1634) Beach PF02138.13 CAM72874.1 - 2.6e-100 335.3 0.0 3.9e-100 334.7 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 CAM72874.1 - 1.5e-22 79.4 0.0 2.6e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 CAM72874.1 - 1.7e-05 24.4 0.3 0.16 11.8 0.0 4.1 3 0 0 3 3 3 2 WD domain, G-beta repeat Sec34 PF04136.10 CAM72875.1 - 2e-05 24.3 0.9 3.6e-05 23.4 0.1 1.7 2 0 0 2 2 2 1 Sec34-like family Syntaxin-6_N PF09177.6 CAM72875.1 - 1.7 9.1 6.9 3.3 8.1 0.5 3.3 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Herpes_IE2_3 PF03361.9 CAM72876.1 - 0.011 15.1 1.5 0.43 9.8 0.2 2.6 2 1 0 2 2 2 0 Herpes virus intermediate/early protein 2/3 Aldedh PF00171.17 CAM72878.1 - 3e-163 543.4 0.2 3.3e-163 543.2 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3253 PF11625.3 CAM72878.1 - 0.055 13.3 2.2 0.15 11.9 1.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3253) DUF1487 PF07368.6 CAM72878.1 - 0.094 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) TPR_11 PF13414.1 CAM72880.1 - 5.9e-31 105.9 7.9 3.1e-08 33.1 0.0 6.2 4 2 3 7 7 7 5 TPR repeat TPR_2 PF07719.12 CAM72880.1 - 7e-16 56.7 16.0 0.0016 18.2 0.1 9.6 10 1 1 11 11 10 4 Tetratricopeptide repeat TPR_1 PF00515.23 CAM72880.1 - 1e-14 53.4 6.4 0.00069 19.1 0.0 8.2 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.1 CAM72880.1 - 2e-10 40.4 14.3 0.041 13.8 0.2 6.7 5 2 3 8 8 8 4 Tetratricopeptide repeat TPR_9 PF13371.1 CAM72880.1 - 1.4e-08 34.4 19.3 1.7e-06 27.7 0.2 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 CAM72880.1 - 1.5e-08 34.8 18.9 0.0022 18.2 0.2 6.7 5 2 3 8 8 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 CAM72880.1 - 7.5e-07 29.2 20.8 0.71 10.6 0.0 9.2 4 3 6 10 10 10 1 Tetratricopeptide repeat TPR_17 PF13431.1 CAM72880.1 - 3.2e-05 23.7 5.9 3.6 8.0 0.0 6.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 CAM72880.1 - 0.00012 21.6 0.1 5.1 7.1 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 CAM72880.1 - 0.00023 21.7 26.9 0.23 12.2 0.1 7.3 7 2 2 9 9 9 3 Tetratricopeptide repeat Apc3 PF12895.2 CAM72880.1 - 0.00077 19.5 12.0 5.6 7.1 0.0 5.9 5 1 1 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 CAM72880.1 - 0.00081 19.0 17.2 0.17 11.7 0.1 6.9 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_20 PF14561.1 CAM72880.1 - 0.019 15.0 0.4 0.29 11.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.1 CAM72880.1 - 0.021 13.8 3.4 1.7 7.6 0.0 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat XRN_N PF03159.13 CAM72881.1 - 3.7e-84 281.8 0.0 3.7e-84 281.8 0.0 1.7 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus Phage_min_cap2 PF06152.6 CAM72882.1 - 1.8 7.4 19.0 0.05 12.5 3.4 2.6 2 1 1 3 3 3 0 Phage minor capsid protein 2 Fmp27_SW PF10305.4 CAM72882.1 - 3.4 8.1 11.1 1.3 9.4 0.3 3.1 1 1 2 3 3 3 0 RNA pol II promoter Fmp27 protein domain MORN PF02493.15 CAM72883.1 - 1.2e-56 185.2 83.8 4.1e-07 29.3 0.4 18.9 20 0 0 20 20 20 15 MORN repeat DUF3048 PF11258.3 CAM72883.1 - 0.059 12.4 3.7 0.085 11.9 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3048) SM-ATX PF14438.1 CAM72883.1 - 0.11 12.4 1.0 1.1e+02 2.7 0.0 4.9 4 1 0 4 4 4 0 Ataxin 2 SM domain Ras PF00071.17 CAM72884.1 - 1.4e-13 50.5 0.0 2.2e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAM72884.1 - 1.4e-13 51.3 0.0 3.6e-13 50.0 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CAM72884.1 - 0.0085 16.0 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CAM72884.1 - 0.045 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 CAM72886.1 - 3.9e-39 133.8 0.0 8.5e-39 132.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM72886.1 - 7.5e-20 70.5 0.0 1.6e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CAM72886.1 - 1.7e-17 62.6 0.0 3.7e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) DEAD PF00270.24 CAM72887.1 - 9.2e-44 148.9 0.2 2.7e-43 147.4 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM72887.1 - 9.7e-25 86.2 0.1 6.8e-24 83.5 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAM72887.1 - 0.00048 20.0 0.1 0.0019 18.0 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Ribosomal_S5_C PF03719.10 CAM72888.1 - 1.1e-15 56.5 0.1 1.8e-15 55.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 CAM72888.1 - 0.012 15.3 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S5, N-terminal domain MVP_shoulder PF11978.3 CAM72889.1 - 1.1e-47 160.7 0.0 1.9e-47 159.9 0.0 1.4 1 0 0 1 1 1 1 Shoulder domain Vault PF01505.13 CAM72889.1 - 6.3e-23 80.5 0.0 3.9e-08 33.2 0.0 4.3 4 0 0 4 4 4 3 Major Vault Protein repeat BORG_CEP PF14957.1 CAM72889.1 - 0.12 13.2 0.8 0.77 10.6 0.0 2.4 2 1 0 2 2 2 0 Cdc42 effector Tfb4 PF03850.9 CAM72889.1 - 0.52 9.5 4.3 0.86 8.7 3.0 1.2 1 0 0 1 1 1 0 Transcription factor Tfb4 CBF PF03914.12 CAM72890.1 - 1.2e-37 128.8 0.8 5.4e-37 126.7 0.0 2.2 2 0 0 2 2 2 1 CBF/Mak21 family NOC3p PF07540.6 CAM72890.1 - 0.00031 20.9 0.0 0.00031 20.9 0.0 2.0 2 0 0 2 2 2 1 Nucleolar complex-associated protein DUF607 PF04678.8 CAM72890.1 - 0.078 12.8 1.7 0.22 11.4 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF607 DivIC PF04977.10 CAM72890.1 - 4.4 6.8 7.2 16 5.0 5.0 1.9 1 0 0 1 1 1 0 Septum formation initiator RPAP3_C PF13877.1 CAM72892.1 - 0.2 11.6 0.0 0.9 9.5 0.0 2.1 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 GAS PF13851.1 CAM72893.1 - 5.3e-64 215.1 29.9 5.3e-64 215.1 20.7 3.9 3 1 1 4 4 4 1 Growth-arrest specific micro-tubule binding DUF3086 PF11285.3 CAM72893.1 - 0.0017 17.2 3.7 0.0017 17.2 2.6 3.0 2 1 0 3 3 3 1 Protein of unknown function (DUF3086) Filament PF00038.16 CAM72893.1 - 0.28 10.5 68.9 0.27 10.6 6.5 4.4 1 1 2 3 3 3 0 Intermediate filament protein DUF607 PF04678.8 CAM72894.1 - 0.015 15.2 0.2 0.015 15.2 0.1 3.2 3 1 0 3 3 3 0 Protein of unknown function, DUF607 PYC_OADA PF02436.13 CAM72894.1 - 0.1 12.0 0.2 0.37 10.1 0.1 2.0 1 0 0 1 1 1 0 Conserved carboxylase domain IncA PF04156.9 CAM72894.1 - 0.11 12.0 22.9 0.15 11.6 3.7 3.9 3 2 0 4 4 4 0 IncA protein CorA PF01544.13 CAM72894.1 - 1.4 7.8 8.6 0.34 9.8 0.5 3.1 3 1 1 4 4 4 0 CorA-like Mg2+ transporter protein TPR_MLP1_2 PF07926.7 CAM72894.1 - 5.7 6.6 23.2 5.1 6.8 1.5 4.3 2 2 1 3 3 3 0 TPR/MLP1/MLP2-like protein Ribosomal_L37ae PF01780.14 CAM72895.1 - 2e-36 123.7 5.1 2.1e-36 123.6 3.6 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family C1_1 PF00130.17 CAM72895.1 - 0.00075 19.1 2.1 0.0011 18.6 1.4 1.2 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) A2L_zn_ribbon PF08792.5 CAM72895.1 - 0.024 14.1 1.2 1.9 8.0 0.0 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain UPF0547 PF10571.4 CAM72895.1 - 0.046 13.4 1.1 7.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 NOB1_Zn_bind PF08772.6 CAM72895.1 - 0.089 12.6 3.7 0.98 9.2 2.6 2.3 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Carla_C4 PF01623.12 CAM72895.1 - 0.094 12.4 1.6 0.12 12.1 1.1 1.3 1 1 0 1 1 1 0 Carlavirus putative nucleic acid binding protein Zn_Tnp_IS1595 PF12760.2 CAM72895.1 - 0.12 12.2 2.5 0.18 11.6 1.7 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-C4_ClpX PF06689.8 CAM72895.1 - 6.6 6.3 7.0 1.2 8.7 2.1 1.8 2 0 0 2 2 2 0 ClpX C4-type zinc finger zf-RING_2 PF13639.1 CAM72896.1 - 6.2e-12 45.1 9.3 1e-11 44.4 6.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CAM72896.1 - 2.4e-11 43.4 7.6 3.7e-11 42.8 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CAM72896.1 - 1.1e-10 41.0 5.9 1.7e-10 40.3 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CAM72896.1 - 7.7e-10 38.3 3.8 1.1e-09 37.8 2.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAM72896.1 - 8.9e-08 31.7 5.9 1.4e-07 31.1 4.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CAM72896.1 - 9.4e-08 31.6 2.3 1.4e-07 31.1 0.4 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CAM72896.1 - 1.2e-07 31.5 6.7 1.9e-07 30.8 4.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 CAM72896.1 - 0.00029 20.3 5.5 0.00085 18.8 3.8 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 CAM72896.1 - 0.0025 17.6 2.3 0.005 16.6 1.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CAM72896.1 - 0.0077 16.3 8.0 0.02 14.9 5.5 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger Baculo_IE-1 PF05290.6 CAM72896.1 - 0.008 15.9 2.1 0.013 15.2 1.5 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_6 PF14835.1 CAM72896.1 - 0.019 14.7 4.2 0.038 13.7 2.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 CAM72896.1 - 0.077 12.5 5.3 0.19 11.3 3.7 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 CAM72896.1 - 0.096 12.2 2.7 0.17 11.4 1.9 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.15 CAM72896.1 - 0.2 11.2 5.7 0.32 10.5 3.9 1.3 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger IBR PF01485.16 CAM72896.1 - 1.5 8.7 7.9 0.67 9.8 3.5 1.7 1 1 0 1 1 1 0 IBR domain Nucleoside_tran PF01733.13 CAM72897.1 - 9e-24 84.1 9.4 9e-24 84.1 6.5 2.1 2 1 0 2 2 2 1 Nucleoside transporter MutS_V PF00488.16 CAM72898.1 - 5.5e-63 212.5 0.2 1.8e-62 210.8 0.2 1.9 1 1 0 1 1 1 1 MutS domain V MutS_I PF01624.15 CAM72898.1 - 1.6e-33 115.0 0.1 3.4e-33 114.0 0.1 1.6 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.13 CAM72898.1 - 4.2e-26 91.9 0.1 2.1e-25 89.7 0.1 2.3 2 1 0 2 2 2 1 MutS domain III AAA_29 PF13555.1 CAM72898.1 - 4.4e-05 22.9 1.1 0.0084 15.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_tran PF00005.22 CAM72898.1 - 0.0036 17.6 0.0 0.014 15.7 0.0 2.0 2 0 0 2 2 2 1 ABC transporter MutS_IV PF05190.13 CAM72898.1 - 0.0056 16.8 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_25 PF13481.1 CAM72898.1 - 0.032 13.6 0.1 0.092 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CAM72898.1 - 0.037 14.0 5.7 1.4 8.8 0.0 4.1 4 1 0 4 4 4 0 AAA ATPase domain AAA_14 PF13173.1 CAM72898.1 - 0.13 12.1 0.0 0.49 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain PMM PF03332.8 CAM72899.1 - 2.3e-101 337.9 0.8 2.6e-101 337.7 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 CAM72899.1 - 1.4e-06 28.1 0.0 2.4e-06 27.3 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 CAM72899.1 - 4.3e-05 22.9 0.0 0.012 14.8 0.0 2.0 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 CAM72899.1 - 0.13 12.6 0.4 8 6.8 0.0 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase 2OG-FeII_Oxy_2 PF13532.1 CAM72900.1 - 1.3e-08 34.9 0.0 2.9e-08 33.7 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 CAM72900.1 - 7.4e-06 26.1 0.0 1.6e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Metallophos PF00149.23 CAM72901.1 - 3.5e-22 78.7 0.1 5.1e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SQS_PSY PF00494.14 CAM72902.1 - 0.0064 15.8 0.4 0.0069 15.7 0.3 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF3900 PF13039.1 CAM72902.1 - 0.03 13.8 0.1 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3900) Sigma70_r1_2 PF00140.15 CAM72903.1 - 0.059 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 XH PF03469.9 CAM72904.1 - 0.047 13.3 5.9 0.1 12.2 1.6 2.4 2 0 0 2 2 2 0 XH domain Peptidase_S49_N PF08496.5 CAM72904.1 - 2 8.2 16.5 1.3 8.8 2.9 2.5 1 1 2 3 3 3 0 Peptidase family S49 N-terminal V_ATPase_I PF01496.14 CAM72904.1 - 6.1 4.5 10.8 7.9 4.1 7.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Erp_C PF06780.6 CAM72904.1 - 7.4 6.3 12.3 8.4 6.2 0.6 3.4 1 1 2 3 3 3 0 Erp protein C-terminus Fez1 PF06818.10 CAM72904.1 - 8.1 6.4 28.0 5.1 7.0 4.6 2.2 1 1 1 2 2 2 0 Fez1 Cpn60_TCP1 PF00118.19 CAM72905.1 - 7.2e-115 384.3 10.2 8.7e-115 384.1 7.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.19 CAM72906.1 - 5.7e-118 394.5 9.6 6.9e-118 394.3 6.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family WD40 PF00400.27 CAM72907.1 - 2.4e-06 27.2 11.2 0.00064 19.5 0.8 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ALG3 PF05208.8 CAM72908.1 - 2.1e-112 376.0 14.5 2.4e-112 375.8 10.1 1.0 1 0 0 1 1 1 1 ALG3 protein Metallophos PF00149.23 CAM72909.1 - 3.6e-20 72.2 0.0 1.2e-16 60.6 0.0 2.8 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase DUF72 PF01904.13 CAM72910.1 - 8.3e-35 120.5 0.1 7.5e-34 117.4 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function DUF72 TPR_11 PF13414.1 CAM72911.1 - 1.1e-17 63.4 3.6 2.1e-09 36.9 0.0 2.7 2 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 CAM72911.1 - 3.8e-12 45.1 8.9 5e-07 29.1 0.5 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 CAM72911.1 - 5.1e-09 35.3 6.6 9.3e-06 25.0 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 CAM72911.1 - 1.5e-08 35.1 22.2 2.7e-05 24.6 7.6 4.4 4 2 2 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 CAM72911.1 - 1.1e-05 24.8 1.0 0.0029 17.2 0.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CAM72911.1 - 1.3e-05 25.0 8.9 0.00049 19.9 1.6 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CAM72911.1 - 2.4e-05 24.5 2.8 2.4e-05 24.5 1.9 4.4 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 CAM72911.1 - 0.00039 20.0 0.6 0.0059 16.3 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 CAM72911.1 - 0.0073 16.6 0.9 0.18 12.3 0.1 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 CAM72911.1 - 0.012 15.9 4.5 0.036 14.3 2.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 CAM72911.1 - 0.031 14.1 1.8 0.19 11.6 1.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat SPA PF08616.5 CAM72913.1 - 0.0051 16.5 0.0 0.014 15.0 0.0 1.7 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 CAM72913.1 - 0.0067 14.9 0.0 0.012 14.1 0.0 1.3 1 0 0 1 1 1 1 Transport protein Avl9 Acetyltransf_10 PF13673.1 CAM72914.1 - 7.9e-05 22.7 0.2 0.00061 19.8 0.0 2.4 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CAM72914.1 - 0.00085 19.3 0.0 0.002 18.0 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 CAM72914.1 - 0.0044 16.8 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DnaJ PF00226.26 CAM72915.1 - 6.5e-21 73.8 0.6 9.5e-21 73.3 0.4 1.3 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 CAM72915.1 - 9.7e-06 25.7 0.7 0.00018 21.7 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) DEAD PF00270.24 CAM72918.1 - 2.5e-45 154.0 0.0 1.3e-44 151.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM72918.1 - 3e-25 87.8 0.0 7.6e-25 86.5 0.1 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAM72918.1 - 0.0026 17.6 0.0 0.02 14.7 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 CAM72918.1 - 0.019 14.5 0.0 0.13 11.8 0.0 2.3 2 1 0 2 2 2 0 AAA domain HAD_2 PF13419.1 CAM72919.1 - 6.4e-11 42.7 1.4 0.0003 21.0 0.0 3.0 3 1 0 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CAM72919.1 - 0.075 12.7 0.0 0.16 11.7 0.0 1.6 1 1 0 1 1 1 0 HAD-hyrolase-like EMP24_GP25L PF01105.19 CAM72920.1 - 1.5e-28 99.7 0.0 2.1e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF1049 PF06305.6 CAM72920.1 - 4 7.0 6.7 0.91 9.0 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Dynein_light PF01221.13 CAM72921.1 - 3.7e-23 81.3 0.0 4.9e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 DUF3646 PF12362.3 CAM72921.1 - 0.0076 16.1 0.0 0.015 15.2 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase III gamma and tau subunits C terminal Ground-like PF04155.13 CAM72921.1 - 0.08 13.2 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Ground-like domain Alpha-amyl_C PF09071.5 CAM72921.1 - 0.086 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Alpha-amylase, C terminal Nol1_Nop2_Fmu PF01189.12 CAM72922.1 - 1.5e-22 80.3 0.0 9.6e-16 57.9 0.0 2.9 2 1 0 2 2 2 2 NOL1/NOP2/sun family FtsJ PF01728.14 CAM72922.1 - 0.0011 19.0 0.0 0.0048 16.9 0.0 2.0 2 0 0 2 2 2 1 FtsJ-like methyltransferase Y_phosphatase PF00102.22 CAM72923.1 - 1.7e-44 151.9 0.0 5.6e-44 150.2 0.0 1.9 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 CAM72923.1 - 6e-05 22.6 0.0 0.00015 21.3 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Choline_transpo PF04515.7 CAM72926.1 - 1.6e-88 296.7 30.1 1.6e-88 296.7 20.9 2.3 1 1 1 2 2 2 2 Plasma-membrane choline transporter PTCB-BRCT PF12738.2 CAM72927.1 - 0.00051 19.8 0.1 0.65 9.8 0.0 2.9 3 0 0 3 3 3 2 twin BRCT domain BRCT PF00533.21 CAM72927.1 - 0.0017 18.4 0.0 0.33 11.1 0.0 3.0 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain Sec1 PF00995.18 CAM72928.1 - 5.8e-116 388.3 0.0 6.6e-116 388.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Spc97_Spc98 PF04130.8 CAM72929.1 - 6.3e-15 54.4 0.0 5.3e-12 44.8 0.0 2.9 3 0 0 3 3 3 2 Spc97 / Spc98 family Peptidase_U35_2 PF14550.1 CAM72929.1 - 0.33 10.5 0.2 0.62 9.6 0.2 1.4 1 0 0 1 1 1 0 Putative phage protease XkdF TGS PF02824.16 CAM72930.1 - 1.6e-19 69.4 0.0 3.2e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 CAM72930.1 - 4.9e-17 61.9 0.0 1.1e-16 60.8 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CAM72930.1 - 2.7e-09 36.4 0.0 8.9e-09 34.8 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B ArgK PF03308.11 CAM72930.1 - 0.0029 16.4 0.1 0.0072 15.1 0.0 1.6 2 0 0 2 2 2 1 ArgK protein GTP_EFTU PF00009.22 CAM72930.1 - 0.0047 16.3 0.4 5 6.5 0.0 3.4 3 1 0 3 3 3 2 Elongation factor Tu GTP binding domain Miro PF08477.8 CAM72930.1 - 0.011 16.2 0.0 0.057 13.9 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 CAM72930.1 - 0.014 15.1 0.2 0.74 9.6 0.0 2.4 1 1 1 2 2 2 0 Dynamin family Guanylate_kin PF00625.16 CAM72931.1 - 1.1e-39 135.7 0.1 4.7e-23 81.5 0.0 3.0 2 1 0 2 2 2 2 Guanylate kinase AAA_33 PF13671.1 CAM72931.1 - 1.4e-07 31.4 0.3 0.00012 22.0 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CAM72931.1 - 9.6e-05 22.4 0.1 0.00024 21.1 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 CAM72931.1 - 0.00069 19.1 0.0 0.0016 17.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CAM72931.1 - 0.00088 19.4 0.0 0.0019 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CAM72931.1 - 0.0014 18.9 0.0 0.032 14.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CAM72931.1 - 0.0015 19.3 0.0 0.0033 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 CAM72931.1 - 0.0039 16.4 0.0 0.006 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Rad17 PF03215.10 CAM72931.1 - 0.0044 15.7 0.0 0.006 15.3 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein MobB PF03205.9 CAM72931.1 - 0.0055 16.4 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 CAM72931.1 - 0.0098 16.1 0.0 0.035 14.3 0.0 1.9 2 0 0 2 2 2 1 ABC transporter RNA_helicase PF00910.17 CAM72931.1 - 0.017 15.2 0.0 0.096 12.8 0.0 2.1 2 0 0 2 2 2 0 RNA helicase MMR_HSR1 PF01926.18 CAM72931.1 - 0.018 15.0 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.7 CAM72931.1 - 0.02 14.5 0.0 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 NACHT domain Mg_chelatase PF01078.16 CAM72931.1 - 0.045 12.9 0.0 0.085 12.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 CAM72931.1 - 0.07 13.0 0.1 0.3 11.0 0.0 2.1 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.9 CAM72931.1 - 0.072 12.8 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TPR_11 PF13414.1 CAM72933.1 - 1.8e-41 139.6 8.9 5.1e-11 42.0 0.2 6.2 4 2 2 6 6 6 6 TPR repeat TPR_1 PF00515.23 CAM72933.1 - 5.2e-31 104.9 6.8 0.00028 20.3 0.0 8.4 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.12 CAM72933.1 - 1.3e-28 96.5 12.2 0.00065 19.4 0.1 9.9 9 1 1 10 10 10 6 Tetratricopeptide repeat TPR_16 PF13432.1 CAM72933.1 - 4.4e-24 84.5 6.8 5e-05 23.8 0.1 7.1 3 2 4 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.1 CAM72933.1 - 3.1e-22 78.3 18.5 1.5e-05 24.8 1.0 6.8 3 2 4 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.1 CAM72933.1 - 1.7e-20 71.4 5.8 0.0016 18.4 0.0 8.3 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 CAM72933.1 - 2.3e-18 64.5 0.0 0.011 15.5 0.0 8.2 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.1 CAM72933.1 - 4.1e-17 62.2 4.9 9.7e-07 29.0 0.1 5.5 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 CAM72933.1 - 6.9e-17 60.4 11.7 0.00016 21.9 0.2 8.9 5 3 5 10 10 9 4 Tetratricopeptide repeat Apc3 PF12895.2 CAM72933.1 - 2.6e-15 56.3 18.2 5.4e-05 23.2 0.0 6.0 2 2 3 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CAM72933.1 - 3.4e-13 49.2 14.4 9.8e-06 25.3 0.1 5.4 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 CAM72933.1 - 1e-11 44.4 7.3 0.83 10.2 0.0 8.7 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_7 PF13176.1 CAM72933.1 - 2.7e-07 29.8 11.5 0.14 11.9 0.1 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_20 PF14561.1 CAM72933.1 - 5.9e-06 26.3 0.6 0.11 12.6 0.1 4.6 4 1 1 5 5 4 1 Tetratricopeptide repeat Paf67 PF10255.4 CAM72933.1 - 0.00047 19.1 0.2 0.49 9.2 0.0 2.5 2 0 0 2 2 2 2 RNA polymerase I-associated factor PAF67 NARP1 PF12569.3 CAM72933.1 - 0.0025 16.6 0.2 5 5.7 0.0 3.5 3 1 1 4 4 4 1 NMDA receptor-regulated protein 1 BTAD PF03704.12 CAM72933.1 - 0.0047 17.2 0.3 0.0047 17.2 0.2 3.6 4 1 0 4 4 3 1 Bacterial transcriptional activator domain TPR_10 PF13374.1 CAM72933.1 - 0.0066 16.3 0.4 0.0066 16.3 0.3 7.0 8 0 0 8 8 8 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 CAM72933.1 - 0.012 15.8 0.2 11 6.2 0.0 3.4 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation ChAPs PF09295.5 CAM72933.1 - 0.014 14.1 0.7 1.2 7.8 0.0 2.8 2 1 2 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF3808 PF10300.4 CAM72933.1 - 0.026 13.1 0.1 0.042 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) Fis1_TPR_C PF14853.1 CAM72933.1 - 0.032 14.1 5.2 12 5.8 0.0 5.5 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat NatB_MDM20 PF09797.4 CAM72933.1 - 0.07 11.8 0.6 0.29 9.8 0.1 1.9 2 0 0 2 2 2 0 N-acetyltransferase B complex (NatB) non catalytic subunit SNAP PF14938.1 CAM72933.1 - 0.43 9.6 2.7 1.7 7.6 0.4 2.9 3 1 0 3 3 3 0 Soluble NSF attachment protein, SNAP DUF3856 PF12968.2 CAM72933.1 - 0.74 9.6 3.2 6 6.6 0.0 3.5 5 0 0 5 5 3 0 Domain of Unknown Function (DUF3856) Apc5 PF12862.2 CAM72933.1 - 1.8 8.4 6.5 21 5.0 0.1 3.5 3 2 1 4 4 3 0 Anaphase-promoting complex subunit 5 Pkinase PF00069.20 CAM72934.1 - 1.1e-50 172.2 0.0 2.6e-50 170.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAM72934.1 - 1.8e-34 119.0 0.0 1.1e-33 116.3 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CAM72934.1 - 3.5e-07 29.4 0.0 4.8e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CAM72934.1 - 0.051 13.2 0.9 0.36 10.5 0.1 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CAM72934.1 - 0.19 10.5 0.1 0.31 9.8 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 zf-Mss51 PF13824.1 CAM72934.1 - 0.26 11.1 2.7 3 7.7 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Ribosomal_S18 PF01084.15 CAM72936.1 - 0.001 18.8 0.0 0.0023 17.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S18 Glucokinase PF02685.11 CAM72937.1 - 7e-16 57.8 0.0 2.8e-15 55.9 0.0 1.8 1 1 0 1 1 1 1 Glucokinase Endonuclease_5 PF04493.9 CAM72938.1 - 7.3e-43 146.3 0.0 1e-42 145.8 0.0 1.2 1 0 0 1 1 1 1 Endonuclease V DUF99 PF01949.11 CAM72938.1 - 0.055 12.5 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF99 adh_short PF00106.20 CAM72939.1 - 8e-13 48.6 5.1 1e-10 41.8 3.6 3.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CAM72939.1 - 7.1e-06 25.7 2.5 2.2e-05 24.2 1.7 1.9 1 1 0 1 1 1 1 KR domain NAD_binding_2 PF03446.10 CAM72939.1 - 0.052 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Gp_dh_C PF02800.15 CAM72940.1 - 1.2e-71 239.2 0.0 1.6e-71 238.8 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CAM72940.1 - 4.1e-61 205.3 0.1 7e-61 204.6 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 CAM72940.1 - 0.0014 18.5 0.7 0.0067 16.3 0.5 2.1 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 CAM72940.1 - 0.054 12.6 0.0 0.099 11.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aminotran_1_2 PF00155.16 CAM72941.1 - 6.3e-62 209.6 0.0 7.6e-62 209.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 CAM72941.1 - 0.00091 18.3 0.0 0.0015 17.6 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 CAM72941.1 - 0.13 11.4 0.0 0.24 10.5 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase Sterol_MT_C PF08498.5 CAM72943.1 - 2.1e-26 91.6 0.1 3.7e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 CAM72943.1 - 6.3e-17 61.8 0.2 7.9e-16 58.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAM72943.1 - 2e-12 46.9 0.1 4.7e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CAM72943.1 - 2.2e-09 36.8 0.1 3.4e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 CAM72943.1 - 5.9e-08 32.6 0.0 1.7e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 CAM72943.1 - 1.2e-07 31.0 0.1 2.7e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 CAM72943.1 - 6.1e-07 29.8 0.4 1.8e-05 25.1 0.0 3.0 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAM72943.1 - 1.9e-06 28.4 0.1 4.5e-05 23.9 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAM72943.1 - 2.2e-06 27.9 0.1 5.9e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CAM72943.1 - 8.3e-05 22.6 0.0 0.0026 17.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.5 CAM72943.1 - 0.00058 19.4 0.4 0.00092 18.8 0.3 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.13 CAM72943.1 - 0.074 12.6 0.2 0.12 11.9 0.1 1.5 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Sterol_MT_C PF08498.5 CAM72944.1 - 4.5e-27 93.7 0.1 7.6e-27 93.0 0.0 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 CAM72944.1 - 6.1e-17 61.9 0.2 7.9e-16 58.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAM72944.1 - 2e-12 46.9 0.1 4.7e-12 45.7 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CAM72944.1 - 2.2e-09 36.8 0.1 3.4e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 CAM72944.1 - 7.1e-08 32.3 0.0 1.7e-07 31.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 CAM72944.1 - 1.3e-07 30.9 0.1 2.7e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 CAM72944.1 - 5.7e-07 29.9 0.4 1.8e-05 25.1 0.0 3.0 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAM72944.1 - 2.2e-06 27.9 0.1 5.9e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAM72944.1 - 2.3e-06 28.1 0.0 4.5e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CAM72944.1 - 0.00025 21.0 0.0 0.0026 17.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.5 CAM72944.1 - 0.00058 19.4 0.4 0.00091 18.8 0.3 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.13 CAM72944.1 - 0.074 12.6 0.2 0.12 11.9 0.1 1.5 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 MTS PF05175.9 CAM72944.1 - 0.097 12.0 0.1 1.5 8.1 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain EF-hand_7 PF13499.1 CAM72945.1 - 0.00025 21.1 0.0 0.00066 19.7 0.0 1.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CAM72945.1 - 0.0055 15.9 0.0 3.7 7.0 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CAM72945.1 - 0.029 14.2 0.0 6.1 7.0 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain EF-hand_8 PF13833.1 CAM72945.1 - 0.12 11.9 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair Cullin_Nedd8 PF10557.4 CAM72946.1 - 2.3e-19 68.9 0.1 5.4e-19 67.7 0.0 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain Peptidase_S9 PF00326.16 CAM72947.1 - 4.2e-32 111.1 0.0 8.1e-32 110.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DPPIV_N PF00930.16 CAM72947.1 - 1.3e-24 86.4 0.0 2.2e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Abhydrolase_5 PF12695.2 CAM72947.1 - 1.6e-05 24.6 0.0 3.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 CAM72947.1 - 0.012 15.1 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Peptidase_S15 PF02129.13 CAM72947.1 - 0.013 14.9 0.1 0.081 12.3 0.0 2.0 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) AOX PF01786.12 CAM72948.1 - 7.4e-83 277.0 0.0 9.1e-83 276.7 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase Spc97_Spc98 PF04130.8 CAM72949.1 - 7.4e-87 291.9 0.0 9.4e-87 291.5 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF309 PF03745.9 CAM72949.1 - 0.004 16.5 0.2 0.046 13.1 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF309) DEAD PF00270.24 CAM72950.1 - 4.2e-34 117.4 0.4 4.6e-33 114.0 0.1 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAM72950.1 - 4.2e-25 87.4 0.1 2e-24 85.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SecA_DEAD PF07517.9 CAM72950.1 - 0.0003 20.1 0.0 0.2 10.9 0.0 2.6 2 0 0 2 2 2 2 SecA DEAD-like domain AAA_22 PF13401.1 CAM72950.1 - 0.091 12.9 1.4 18 5.5 0.0 3.8 3 1 1 4 4 4 0 AAA domain HAUS6_N PF14661.1 CAM72951.1 - 4.3 6.6 14.5 5.6 6.2 10.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Ycf1 PF05758.7 CAM72951.1 - 8.1 4.0 9.9 9.5 3.7 6.8 1.1 1 0 0 1 1 1 0 Ycf1 Ribosomal_L22e PF01776.12 CAM72952.1 - 1.8e-39 134.2 3.2 2.3e-39 133.8 2.2 1.2 1 0 0 1 1 1 1 Ribosomal L22e protein family Cytochrom_C550 PF14495.1 CAM72952.1 - 0.086 12.2 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c-550 domain Asparaginase PF00710.15 CAM72953.1 - 2.3e-65 220.5 0.0 2.6e-65 220.3 0.0 1.0 1 0 0 1 1 1 1 Asparaginase TPR_17 PF13431.1 CAM72954.1 - 5e-06 26.2 6.2 0.00057 19.8 0.4 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 CAM72954.1 - 2.7e-05 24.3 0.1 0.0081 16.4 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 CAM72954.1 - 6.1e-05 22.5 0.2 0.0017 17.9 0.1 2.9 3 0 0 3 3 3 1 TPR repeat TPR_14 PF13428.1 CAM72954.1 - 0.00039 20.7 2.2 0.29 11.9 0.3 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 CAM72954.1 - 0.00077 19.1 2.1 0.0016 18.2 0.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 CAM72954.1 - 0.0033 18.0 0.4 0.078 13.6 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 CAM72954.1 - 0.0076 15.8 1.7 0.042 13.4 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.9 CAM72954.1 - 0.023 15.0 0.6 0.098 13.1 0.4 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 CAM72954.1 - 0.031 14.7 0.4 0.12 12.8 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 CAM72954.1 - 0.034 14.0 0.0 0.15 12.0 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 CAM72954.1 - 0.034 13.9 0.5 0.33 10.8 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 CAM72954.1 - 0.062 13.1 0.1 0.16 11.8 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Apc3 PF12895.2 CAM72954.1 - 0.099 12.7 5.0 0.16 12.1 0.0 3.1 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Peptidase_M3 PF01432.15 CAM72955.1 - 5.7e-74 249.7 0.3 1.7e-58 198.7 0.2 2.0 2 0 0 2 2 2 2 Peptidase family M3 DnaJ PF00226.26 CAM72957.1 - 1e-22 79.6 0.4 2.7e-22 78.2 0.1 1.9 2 0 0 2 2 2 1 DnaJ domain Aa_trans PF01490.13 CAM72958.1 - 8e-44 149.7 0.1 7.4e-36 123.5 0.0 2.5 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein Methyltransf_26 PF13659.1 CAM72959.1 - 5.6e-13 48.9 0.0 1.4e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CAM72959.1 - 9.4e-13 47.8 0.0 1.5e-10 40.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.1 CAM72959.1 - 1.3e-10 41.1 0.0 4.1e-10 39.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAM72959.1 - 8.8e-09 35.9 0.0 1.8e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CAM72959.1 - 2.4e-06 26.8 0.0 4.8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 CAM72959.1 - 0.00012 21.3 0.0 0.00019 20.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 CAM72959.1 - 0.00019 21.7 0.0 0.00036 20.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CAM72959.1 - 0.0005 20.4 0.0 0.0011 19.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 CAM72959.1 - 0.0017 17.9 0.0 0.0025 17.4 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_12 PF08242.7 CAM72959.1 - 0.016 15.6 0.0 0.042 14.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 CAM72959.1 - 0.024 14.2 1.4 4.3 6.8 1.0 2.4 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_23 PF13489.1 CAM72959.1 - 0.041 13.6 0.0 0.095 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 CAM72959.1 - 0.054 12.9 0.0 0.088 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase FmrO PF07091.6 CAM72959.1 - 0.099 11.6 0.1 0.7 8.8 0.0 2.2 3 0 0 3 3 3 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_15 PF09445.5 CAM72959.1 - 0.15 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase TRM PF02005.11 CAM72959.1 - 0.16 10.8 0.0 0.21 10.4 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase DUF2870 PF11069.3 CAM72960.1 - 4.2e-38 129.3 0.1 9.7e-38 128.1 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) BBS2_C PF14782.1 CAM72960.1 - 0.077 11.5 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Ribosomal_L18e PF00828.14 CAM72961.1 - 1.6e-20 73.7 0.2 1.6e-20 73.7 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 ABC1 PF03109.11 CAM72963.1 - 2.8e-25 88.5 0.0 5.1e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Alpha_kinase PF02816.13 CAM72964.1 - 6.1e-58 195.6 0.1 7.9e-58 195.2 0.1 1.1 1 0 0 1 1 1 1 Alpha-kinase family UIM PF02809.15 CAM72964.1 - 4.6 7.0 5.0 0.61 9.8 0.5 1.9 2 0 0 2 2 2 0 Ubiquitin interaction motif Alpha_kinase PF02816.13 CAM72965.1 - 8.3e-103 341.9 0.0 2.3e-44 151.3 0.0 3.3 3 0 0 3 3 3 3 Alpha-kinase family Alpha_kinase PF02816.13 CAM72966.1 - 2.2e-66 223.1 0.3 2.8e-66 222.7 0.2 1.1 1 0 0 1 1 1 1 Alpha-kinase family BBS2_N PF14781.1 CAM72969.1 - 0.0042 16.7 0.1 2.6 7.6 0.0 2.8 2 1 0 2 2 2 2 Ciliary BBSome complex subunit 2, N-terminal zf-HC5HC2H PF13771.1 CAM72970.1 - 2e-07 31.0 7.3 2e-07 31.0 5.1 3.3 3 1 1 4 4 4 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 CAM72970.1 - 3.4e-05 23.8 11.3 3.4e-05 23.8 7.8 3.3 2 2 1 3 3 3 1 PHD-zinc-finger like domain Transmemb_17 PF09799.4 CAM72971.1 - 8.7e-10 38.9 12.8 1.2e-09 38.4 8.9 1.2 1 0 0 1 1 1 1 Predicted membrane protein SNARE PF05739.14 CAM72972.1 - 1.4e-05 24.6 0.9 4.4e-05 23.0 0.6 1.9 1 0 0 1 1 1 1 SNARE domain Peptidase_S9 PF00326.16 CAM72975.1 - 7.3e-07 28.6 0.5 1.8e-05 24.0 0.1 2.7 2 1 1 3 3 3 1 Prolyl oligopeptidase family Esterase_phd PF10503.4 CAM72975.1 - 1e-06 28.1 1.3 3.4e-06 26.4 0.9 1.8 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.11 CAM72975.1 - 3.2e-06 26.7 0.0 5.9e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 CAM72975.1 - 1.2e-05 25.1 0.1 2.9e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 CAM72975.1 - 2.9e-05 23.6 0.0 0.00024 20.6 0.0 2.2 1 1 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.2 CAM72975.1 - 9.6e-05 22.3 0.3 0.035 13.9 0.1 3.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 CAM72975.1 - 0.014 14.9 0.1 0.029 13.9 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold FSH1 PF03959.8 CAM72975.1 - 0.022 14.2 0.0 0.05 13.0 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) VIT1 PF01988.14 CAM72975.1 - 0.062 12.7 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 VIT family Ribosomal_L10 PF00466.15 CAM72976.1 - 5.9e-19 67.8 0.1 8.9e-19 67.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 VPS9 PF02204.13 CAM72977.1 - 1.9e-29 101.7 0.0 5.6e-29 100.2 0.0 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Prok-TraM PF09228.5 CAM72977.1 - 0.038 14.1 0.8 6 7.0 0.1 3.3 3 0 0 3 3 3 0 Prokaryotic Transcriptional repressor TraM HALZ PF02183.13 CAM72978.1 - 0.0063 16.2 1.9 0.0087 15.7 0.1 2.1 2 0 0 2 2 2 1 Homeobox associated leucine zipper Transcrip_act PF04949.8 CAM72978.1 - 0.023 14.3 3.0 0.028 14.0 2.1 1.0 1 0 0 1 1 1 0 Transcriptional activator DUF3138 PF11336.3 CAM72978.1 - 0.029 12.5 0.4 0.03 12.5 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF904 PF06005.7 CAM72978.1 - 0.043 14.0 9.5 1.5 9.1 6.5 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF904) MAD PF05557.8 CAM72978.1 - 0.056 11.5 7.0 0.082 10.9 4.8 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein TMF_DNA_bd PF12329.3 CAM72978.1 - 0.094 12.5 9.4 1.6 8.5 0.2 2.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 CAM72978.1 - 0.12 11.9 6.4 0.17 11.4 4.5 1.2 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 CAM72978.1 - 0.27 11.5 6.0 0.64 10.3 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) GAS PF13851.1 CAM72978.1 - 0.44 9.7 5.8 0.55 9.3 4.0 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Leu_zip PF15294.1 CAM72978.1 - 0.59 9.1 8.1 1.1 8.2 5.6 1.4 1 1 0 1 1 1 0 Leucine zipper ALMS_motif PF15309.1 CAM72978.1 - 0.68 9.7 6.2 0.11 12.3 1.0 1.9 2 0 0 2 2 2 0 ALMS motif Prefoldin_2 PF01920.15 CAM72978.1 - 0.91 9.3 6.0 0.76 9.5 0.2 2.5 2 1 0 2 2 2 0 Prefoldin subunit FlaC_arch PF05377.6 CAM72978.1 - 1.1 9.2 3.1 2.7 7.9 0.1 2.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) FUSC PF04632.7 CAM72978.1 - 1.3 7.3 4.0 1.4 7.2 2.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Enkurin PF13864.1 CAM72978.1 - 1.3 9.2 5.7 0.26 11.5 0.4 2.0 1 1 1 2 2 2 0 Calmodulin-binding Cortex-I_coil PF09304.5 CAM72978.1 - 1.6 8.8 10.3 0.91 9.5 2.2 2.3 1 1 1 2 2 2 0 Cortexillin I, coiled coil Mod_r PF07200.8 CAM72978.1 - 1.9 8.4 7.5 7.9 6.3 1.1 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein CCDC-167 PF15188.1 CAM72978.1 - 2.2 8.2 10.3 1.4 8.9 0.2 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 TSC22 PF01166.13 CAM72978.1 - 2.4 8.1 5.8 3 7.8 1.6 2.5 2 1 0 2 2 2 0 TSC-22/dip/bun family DUF4355 PF14265.1 CAM72978.1 - 3.4 7.6 9.2 3.1 7.7 4.9 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4355) DUF4140 PF13600.1 CAM72978.1 - 4.8 7.6 8.3 4.7 7.7 1.3 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) APG6 PF04111.7 CAM72978.1 - 4.9 6.0 7.1 7.1 5.5 4.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 bZIP_2 PF07716.10 CAM72978.1 - 7.7 6.4 13.1 2.9 7.7 0.6 3.0 2 1 1 3 3 3 0 Basic region leucine zipper Cyt-b5 PF00173.23 CAM72979.1 - 3.8e-15 55.4 0.0 4.2e-15 55.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MAGP PF05507.6 CAM72980.1 - 0.02 14.7 0.1 1.2 8.8 0.0 2.8 2 0 0 2 2 2 0 Microfibril-associated glycoprotein (MAGP) Abhydrolase_6 PF12697.2 CAM72981.1 - 1.8e-11 44.3 12.7 8.4e-07 29.0 6.8 3.0 2 1 0 2 2 2 2 Alpha/beta hydrolase family End_tail_spike PF12219.3 CAM72981.1 - 0.093 12.5 0.9 0.27 11.0 0.1 2.1 2 0 0 2 2 2 0 Catalytic domain of bacteriophage endosialidase WD40 PF00400.27 CAM72982.1 - 3.8e-18 64.6 3.8 8.9e-05 22.2 0.0 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat Flavodoxin_1 PF00258.20 CAM72983.1 - 6.9e-31 107.1 0.0 2.6e-23 82.5 0.0 4.4 5 0 0 5 5 5 3 Flavodoxin FAD_binding_1 PF00667.15 CAM72983.1 - 4.5e-20 72.0 0.0 1e-19 70.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 CAM72983.1 - 2.2e-12 47.5 0.0 6.3e-12 46.0 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain RabGAP-TBC PF00566.13 CAM72984.1 - 0.00059 19.3 0.1 0.0018 17.7 0.1 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DSX_dimer PF08828.5 CAM72984.1 - 0.22 11.0 0.8 0.8 9.2 0.3 2.0 2 0 0 2 2 2 0 Doublesex dimerisation domain PIG-P PF08510.7 CAM72986.1 - 3.2e-32 110.7 1.0 3.8e-32 110.5 0.7 1.0 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.7 CAM72986.1 - 0.29 11.4 7.7 0.63 10.3 5.3 1.6 1 1 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF2347 PF09804.4 CAM72987.1 - 0.0054 16.0 0.1 0.069 12.4 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) DUF260 PF03195.9 CAM72987.1 - 0.016 15.5 0.7 3.9 7.8 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function DUF260 DNA_ligase_A_N PF04675.9 CAM72987.1 - 0.031 14.0 0.4 1.2 8.9 0.2 2.6 1 1 1 2 2 2 0 DNA ligase N terminus Peptidase_M35 PF02102.10 CAM72987.1 - 0.083 11.5 1.8 0.13 10.8 1.3 1.2 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family DUF1749 PF08538.5 CAM72989.1 - 1.5e-14 53.5 0.0 2.1e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 CAM72989.1 - 1.7e-08 34.6 2.6 2.3e-08 34.1 1.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Methyltransf_26 PF13659.1 CAM72991.1 - 2.4e-05 24.3 0.5 9.2e-05 22.4 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase domain Spermine_synth PF01564.12 CAM72991.1 - 0.001 18.0 0.0 0.0016 17.4 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_24 PF13578.1 CAM72991.1 - 0.0025 18.6 0.0 0.0088 16.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAM72991.1 - 0.041 14.4 0.0 0.12 12.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain MetW PF07021.7 CAM72991.1 - 0.15 11.3 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PPR_2 PF13041.1 CAM72992.1 - 7.1e-41 137.9 10.6 3.1e-16 59.0 0.6 5.1 2 1 3 5 5 5 5 PPR repeat family PPR_3 PF13812.1 CAM72992.1 - 3.8e-37 123.4 5.9 8.3e-09 35.0 0.1 6.3 6 0 0 6 6 6 5 Pentatricopeptide repeat domain PPR PF01535.15 CAM72992.1 - 8.6e-35 116.3 2.4 2.2e-06 27.2 0.0 6.2 6 0 0 6 6 6 5 PPR repeat PPR_1 PF12854.2 CAM72992.1 - 2.5e-28 97.2 1.5 1.5e-09 37.1 0.0 6.2 6 0 0 6 6 6 4 PPR repeat TPR_14 PF13428.1 CAM72992.1 - 1.1e-05 25.6 0.2 38 5.3 0.0 5.5 5 1 1 6 6 6 0 Tetratricopeptide repeat ECSIT PF06239.6 CAM72992.1 - 0.015 14.1 0.0 2.9 6.6 0.1 3.4 2 1 2 4 4 4 0 Evolutionarily conserved signalling intermediate in Toll pathway BTAD PF03704.12 CAM72992.1 - 0.032 14.5 3.3 5.4 7.3 0.2 3.8 4 0 0 4 4 4 0 Bacterial transcriptional activator domain WD40 PF00400.27 CAM72993.1 - 2.2e-49 163.6 14.5 8e-09 35.0 0.0 7.7 8 0 0 8 8 8 7 WD domain, G-beta repeat AAA_16 PF13191.1 CAM72994.1 - 0.00064 19.7 0.0 0.0022 18.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Miro PF08477.8 CAM72994.1 - 0.015 15.7 0.0 0.25 11.8 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein Ras PF00071.17 CAM72994.1 - 0.021 14.1 0.0 0.29 10.5 0.0 2.2 2 0 0 2 2 2 0 Ras family SRPRB PF09439.5 CAM72994.1 - 0.066 12.4 0.0 0.35 10.0 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit LRR_4 PF12799.2 CAM72995.1 - 1.5e-36 123.4 22.3 0.0016 17.9 0.2 13.4 7 4 4 13 13 13 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM72995.1 - 9.8e-21 73.2 43.8 9.7e-06 25.2 1.0 10.5 6 3 8 14 14 14 9 Leucine rich repeat LRR_6 PF13516.1 CAM72995.1 - 1.1e-11 43.5 37.4 0.0032 17.3 0.1 15.6 17 1 1 18 18 18 4 Leucine Rich repeat LRR_1 PF00560.28 CAM72995.1 - 0.0014 18.3 46.9 20 5.7 0.0 15.8 17 1 0 17 17 17 3 Leucine Rich Repeat 2_5_RNA_ligase2 PF13563.1 CAM72997.1 - 0.00025 20.8 0.0 0.00083 19.1 0.0 1.7 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily MtN3_slv PF03083.11 CAM72998.1 - 3.7e-24 84.3 19.7 1.3e-13 50.5 0.5 3.0 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange UNC-93 PF05978.11 CAM72998.1 - 0.021 14.3 2.2 0.021 14.3 1.5 2.1 1 1 0 2 2 2 0 Ion channel regulatory protein UNC-93 LRR_4 PF12799.2 CAM72999.1 - 3.5e-15 55.2 3.6 8.3e-05 22.1 0.5 4.5 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAM72999.1 - 1.8e-11 43.5 7.3 9.8e-06 25.2 0.5 2.7 2 0 0 2 2 2 2 Leucine rich repeat LRR_9 PF14580.1 CAM72999.1 - 5.4e-08 32.5 0.6 1.3e-06 28.0 0.4 2.5 1 1 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.28 CAM72999.1 - 3.9e-05 23.1 9.2 16 6.0 0.1 6.5 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_6 PF13516.1 CAM72999.1 - 0.073 13.1 15.9 4.6 7.6 0.5 6.0 5 2 1 6 6 6 0 Leucine Rich repeat LRR_7 PF13504.1 CAM72999.1 - 0.51 10.7 21.0 12 6.6 0.1 7.2 8 0 0 8 8 8 0 Leucine rich repeat RNase_PH PF01138.16 CAM73000.1 - 3e-14 53.4 0.2 4.8e-14 52.8 0.2 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Orexin_rec2 PF03827.8 CAM73000.1 - 0.076 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Orexin receptor type 2 Clathrin PF00637.15 CAM73001.1 - 3.3e-07 29.9 2.0 7.2e-07 28.8 0.1 2.6 3 0 0 3 3 3 1 Region in Clathrin and VPS zf-RING_2 PF13639.1 CAM73001.1 - 0.00094 18.9 0.2 0.0039 16.9 0.1 2.1 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CAM73001.1 - 0.0016 18.5 1.9 0.0037 17.3 1.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger Vps8 PF12816.2 CAM73001.1 - 0.0096 15.1 0.0 13 5.0 0.0 3.7 3 0 0 3 3 3 1 Golgi CORVET complex core vacuolar protein 8 zf-Mss51 PF13824.1 CAM73002.1 - 1.5 8.7 5.1 17 5.3 0.3 3.1 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF3533 PF12051.3 CAM73002.1 - 3 6.5 5.3 4.2 6.0 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) CH PF00307.26 CAM73003.1 - 2.9e-06 27.2 0.0 6.6e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain Es2 PF09751.4 CAM73003.1 - 0.14 11.5 1.6 0.13 11.6 0.1 1.6 2 0 0 2 2 2 0 Nuclear protein Es2 PSP1 PF04468.7 CAM73004.1 - 0.035 14.0 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 PSP1 C-terminal conserved region Tubulin PF00091.20 CAM73005.1 - 2e-35 122.5 1.5 6.3e-25 88.2 0.0 3.1 2 1 1 3 3 3 2 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.1 CAM73005.1 - 0.023 13.6 0.0 0.042 12.7 0.0 1.3 1 0 0 1 1 1 0 Tubulin like Ribosomal_S2 PF00318.15 CAM73007.1 - 1.6e-44 151.6 0.2 2.5e-41 141.2 0.1 2.1 1 1 0 1 1 1 1 Ribosomal protein S2 Sulfotransfer_1 PF00685.22 CAM73007.1 - 0.025 13.8 0.0 0.033 13.4 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase domain DUF3113 PF11310.3 CAM73008.1 - 0.0032 17.1 2.0 0.57 9.9 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF3113) Cep57_CLD_2 PF14197.1 CAM73008.1 - 0.012 15.5 7.3 0.012 15.5 5.0 11.2 7 5 6 13 13 13 0 Centrosome localisation domain of PPC89 FliJ PF02050.11 CAM73008.1 - 0.013 15.5 17.2 0.013 15.5 11.9 8.8 3 2 6 9 9 9 0 Flagellar FliJ protein DUF3315 PF11776.3 CAM73008.1 - 1.2 8.7 3.0 0.56 9.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3315) FliD_N PF02465.13 CAM73009.1 - 0.014 15.7 5.9 0.35 11.2 0.0 3.2 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus ORF6C PF10552.4 CAM73009.1 - 0.13 11.9 0.2 0.13 11.9 0.1 2.7 4 0 0 4 4 4 0 ORF6C domain Syntaxin-6_N PF09177.6 CAM73009.1 - 0.21 12.0 15.5 4.5 7.7 1.4 4.2 3 2 1 4 4 4 0 Syntaxin 6, N-terminal Pex19 PF04614.7 CAM73009.1 - 0.42 10.1 5.8 1.9 8.0 2.2 2.1 1 1 1 2 2 2 0 Pex19 protein family Lectin_N PF03954.9 CAM73009.1 - 0.64 9.4 7.4 7.3 5.9 1.7 3.2 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Gp-FAR-1 PF05823.7 CAM73009.1 - 0.86 9.5 6.9 0.12 12.2 1.3 2.2 2 1 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF948 PF06103.6 CAM73009.1 - 1.1 9.2 6.5 4.2 7.2 0.3 3.7 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.7 CAM73009.1 - 1.4 8.7 11.6 0.51 10.1 1.5 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Tho2 PF11262.3 CAM73009.1 - 1.6 7.6 5.4 0.3 10.0 0.1 2.3 2 1 1 3 3 3 0 Transcription factor/nuclear export subunit protein 2 GAS PF13851.1 CAM73009.1 - 1.8 7.7 21.7 0.061 12.5 2.0 3.2 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.7 CAM73009.1 - 1.8 8.3 8.3 21 4.9 2.5 3.7 2 1 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.6 CAM73009.1 - 3.6 7.4 17.9 0.07 12.9 1.2 3.7 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 zf-C4H2 PF10146.4 CAM73009.1 - 4.2 7.3 20.0 2.8 7.9 4.2 3.3 1 1 1 2 2 2 0 Zinc finger-containing protein IncA PF04156.9 CAM73009.1 - 7.2 6.1 34.9 0.1 12.1 6.5 3.3 2 1 0 3 3 3 0 IncA protein Hexapep PF00132.19 CAM73010.1 - 5.1e-10 38.4 13.7 0.00036 19.9 0.1 4.5 3 1 0 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NOB1_Zn_bind PF08772.6 CAM73012.1 - 6.9e-29 99.4 0.2 1.3e-28 98.5 0.1 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like DZR PF12773.2 CAM73012.1 - 0.013 15.2 0.4 0.027 14.2 0.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon DUF35_N PF12172.3 CAM73012.1 - 0.048 13.5 1.6 0.13 12.2 1.1 1.7 1 1 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-ribbon_3 PF13248.1 CAM73012.1 - 0.06 12.5 0.8 0.11 11.7 0.5 1.5 1 0 0 1 1 1 0 zinc-ribbon domain AF1Q PF15017.1 CAM73012.1 - 0.56 10.1 7.7 2.1 8.2 5.3 2.0 1 1 0 1 1 1 0 Drug resistance and apoptosis regulator CK_II_beta PF01214.13 CAM73015.1 - 1.9e-75 252.4 0.0 2.3e-75 252.1 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DUF4496 PF14908.1 CAM73017.1 - 1.1e-30 106.4 0.1 1.4e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4496) Ribosomal_S2 PF00318.15 CAM73018.1 - 1.6e-44 151.6 0.2 2.5e-41 141.2 0.1 2.1 1 1 0 1 1 1 1 Ribosomal protein S2 Sulfotransfer_1 PF00685.22 CAM73018.1 - 0.025 13.8 0.0 0.033 13.4 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase domain Porin_3 PF01459.17 CAM73019.1 - 0.03 13.6 0.3 0.098 11.9 0.2 2.0 1 1 0 1 1 1 0 Eukaryotic porin VHS PF00790.14 CAM73020.1 - 1.9e-11 43.7 0.1 2.7e-09 36.7 0.0 2.2 2 0 0 2 2 2 2 VHS domain Kinesin PF00225.18 CAM73021.1 - 7.8e-24 83.9 11.2 9.4e-17 60.7 0.0 3.7 3 2 0 4 4 4 2 Kinesin motor domain MIF4G PF02854.14 CAM73022.1 - 1.5e-14 53.8 0.2 1.5e-14 53.8 0.1 2.0 2 1 0 2 2 2 1 MIF4G domain MA3 PF02847.12 CAM73022.1 - 1.6e-11 43.9 1.0 1.6e-11 43.9 0.7 2.1 2 0 0 2 2 2 1 MA3 domain VPS28 PF03997.7 CAM73023.1 - 2.1e-37 128.5 0.1 2.6e-37 128.2 0.1 1.1 1 0 0 1 1 1 1 VPS28 protein Phage_Mu_Gam PF07352.7 CAM73023.1 - 0.0061 16.0 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein Aldedh PF00171.17 CAM73024.1 - 1.9e-131 438.5 1.2 2.2e-131 438.4 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SNF2_N PF00176.18 CAM73025.1 - 3.8e-71 239.3 0.3 8.4e-71 238.2 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CAM73025.1 - 2.3e-14 53.0 0.0 5e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAM73025.1 - 2.4e-06 27.5 0.0 1.3e-05 25.1 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CAM73025.1 - 0.00049 19.6 0.0 0.001 18.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Sec8_exocyst PF04048.9 CAM73025.1 - 0.029 13.9 0.0 0.088 12.4 0.0 1.7 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain AAA_22 PF13401.1 CAM73025.1 - 0.033 14.3 0.0 0.18 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain PQQ_3 PF13570.1 CAM73027.1 - 0.66 10.3 5.3 0.53 10.6 0.4 3.5 3 0 0 3 3 3 0 PQQ-like domain PRKCSH PF07915.8 CAM73028.1 - 0.35 11.7 2.0 3.4 8.5 1.4 2.2 1 1 0 1 1 1 0 Glucosidase II beta subunit-like protein TPR_17 PF13431.1 CAM73029.1 - 0.099 12.8 0.4 24 5.4 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_hydro_65m PF03632.10 CAM73030.1 - 6.7e-68 229.0 0.0 1.4e-67 227.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 CAM73030.1 - 8e-18 64.6 0.0 1.9e-17 63.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain HAD_2 PF13419.1 CAM73030.1 - 3.8e-08 33.7 0.6 2.7e-07 30.9 0.0 2.6 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Glyco_hydro_65C PF03633.10 CAM73030.1 - 0.011 15.8 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, C-terminal domain MtrG PF04210.8 CAM73031.1 - 0.059 13.0 12.6 27 4.5 0.1 5.1 5 0 0 5 5 5 0 Tetrahydromethanopterin S-methyltransferase, subunit G Adaptin_N PF01602.15 CAM73032.1 - 3e-78 263.4 0.0 3.8e-78 263.0 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 CAM73032.1 - 2.6e-07 30.8 7.8 0.00013 22.1 1.8 4.1 2 2 1 3 3 3 2 HEAT repeats HEAT PF02985.17 CAM73032.1 - 8.3e-06 25.4 3.1 0.87 9.8 0.1 4.3 3 0 0 3 3 3 3 HEAT repeat HEAT_EZ PF13513.1 CAM73032.1 - 1.6 9.3 12.7 1.1 9.8 0.8 4.2 3 1 2 5 5 5 0 HEAT-like repeat Exo_endo_phos PF03372.18 CAM73033.1 - 1.4e-15 57.9 0.0 9.6e-13 48.6 0.0 2.3 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CAM73033.1 - 1e-05 25.0 0.0 0.0033 17.0 0.0 2.5 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase HEAT PF02985.17 CAM73034.1 - 2.5e-05 23.9 3.5 0.17 12.0 0.0 5.6 4 1 1 5 5 5 2 HEAT repeat Arm PF00514.18 CAM73034.1 - 0.047 13.5 0.7 11 6.0 0.1 3.4 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat TSKS PF15358.1 CAM73035.1 - 0.017 13.3 1.5 0.67 8.0 0.4 2.1 1 1 1 2 2 2 0 Testis-specific serine kinase substrate DUF4142 PF13628.1 CAM73035.1 - 0.021 14.8 4.1 1.2 9.1 1.7 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4142) RdRP_4 PF02123.11 CAM73035.1 - 0.24 10.1 4.5 0.52 8.9 3.1 1.5 1 1 0 1 1 1 0 Viral RNA-directed RNA-polymerase Cnl2_NKP2 PF09447.5 CAM73035.1 - 1.2 8.8 7.7 3.1 7.5 0.5 2.8 3 0 0 3 3 3 0 Cnl2/NKP2 family protein Y_phosphatase PF00102.22 CAM73036.1 - 1.5e-66 224.1 0.0 2e-66 223.7 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 CAM73036.1 - 0.00072 19.1 0.0 0.0017 17.9 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CAM73036.1 - 0.00078 19.7 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 CAM73036.1 - 0.023 14.7 0.0 0.087 12.8 0.0 1.7 1 1 0 1 1 1 0 Inositol hexakisphosphate Pyr_redox_2 PF07992.9 CAM73037.1 - 1.6e-30 106.5 0.0 9.8e-30 103.9 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CAM73037.1 - 3.3e-10 40.2 0.0 2.9e-07 30.7 0.1 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CAM73037.1 - 6.5e-06 25.2 0.0 0.0043 15.9 0.0 2.8 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_3 PF13738.1 CAM73037.1 - 3.3e-05 24.0 0.0 0.00021 21.4 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CAM73037.1 - 0.0027 17.7 0.0 0.88 9.6 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 CAM73037.1 - 0.0037 16.1 0.3 0.55 9.0 0.0 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A DAO PF01266.19 CAM73037.1 - 0.0045 15.9 1.1 1.7 7.4 0.0 3.0 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pribosyltran_N PF13793.1 CAM73038.1 - 4.8e-39 132.7 0.3 2e-38 130.6 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 CAM73038.1 - 4.8e-29 101.4 3.9 1.3e-28 99.9 1.1 2.3 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 CAM73038.1 - 8.5e-13 48.1 0.2 2.6e-12 46.5 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CAM73038.1 - 6.8e-05 22.1 0.5 0.00013 21.2 0.1 1.7 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase DUF2745 PF10922.3 CAM73038.1 - 0.13 12.1 0.1 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2745) BCS1_N PF08740.6 CAM73039.1 - 5.2e-38 130.5 1.1 7.3e-38 130.0 0.8 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 CAM73039.1 - 6.5e-11 42.5 0.0 2.8e-05 24.3 0.0 2.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CAM73039.1 - 0.00012 22.8 0.0 0.00027 21.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CAM73039.1 - 0.00053 19.0 0.0 0.00094 18.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CAM73039.1 - 0.00082 19.0 0.0 0.0039 16.9 0.0 2.2 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 CAM73039.1 - 0.0021 17.8 0.0 0.0048 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CAM73039.1 - 0.0035 17.2 0.0 0.013 15.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 CAM73039.1 - 0.0053 16.3 0.0 0.0097 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CAM73039.1 - 0.0055 16.7 0.2 0.07 13.1 0.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.8 CAM73039.1 - 0.018 13.7 0.0 0.031 12.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus KaiC PF06745.8 CAM73039.1 - 0.061 12.4 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_3 PF07726.6 CAM73039.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 CAM73039.1 - 0.14 11.6 0.7 4 6.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain AIRS_C PF02769.17 CAM73040.1 - 4.7e-15 55.9 0.0 9.6e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.19 CAM73040.1 - 6.1e-08 32.8 0.0 1.3e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Extensin-like_C PF06904.7 CAM73040.1 - 0.082 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Extensin-like protein C-terminus KH_1 PF00013.24 CAM73041.1 - 1.1e-05 24.9 0.0 2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 CAM73041.1 - 0.0014 18.1 0.0 0.0031 17.1 0.0 1.6 1 0 0 1 1 1 1 KH domain L27_1 PF09058.5 CAM73041.1 - 0.11 12.3 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 L27_1 Ribosomal_60s PF00428.14 CAM73041.1 - 1.3 9.4 13.2 3.3 8.1 9.1 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein TylF PF05711.6 CAM73042.1 - 1.8e-16 59.9 0.8 3.3e-08 32.9 0.7 2.7 2 1 0 2 2 2 2 Macrocin-O-methyltransferase (TylF) Methyltransf_24 PF13578.1 CAM73042.1 - 3.6e-08 34.2 0.1 4.4e-07 30.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain CmcI PF04989.7 CAM73042.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Cephalosporin hydroxylase SEP PF08059.8 CAM73043.1 - 5.8e-07 29.7 0.0 1.5e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 CAM73043.1 - 2.2e-05 24.4 0.0 4.7e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 UBX domain IncA PF04156.9 CAM73043.1 - 0.00015 21.4 2.1 0.00015 21.4 1.5 2.2 3 0 0 3 3 3 1 IncA protein Spc24 PF08286.6 CAM73043.1 - 0.071 12.8 2.8 0.14 11.8 2.0 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Mnd1 PF03962.10 CAM73043.1 - 0.16 11.5 3.1 0.33 10.5 2.1 1.4 1 0 0 1 1 1 0 Mnd1 family APG6 PF04111.7 CAM73043.1 - 0.31 10.0 6.4 0.54 9.2 4.4 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 CAM73043.1 - 0.31 9.3 1.5 0.48 8.7 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TPR_MLP1_2 PF07926.7 CAM73043.1 - 0.93 9.2 11.9 0.041 13.6 3.9 1.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.3 CAM73043.1 - 8 6.2 11.8 0.41 10.3 4.0 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DAO PF01266.19 CAM73045.1 - 2.5e-41 141.8 0.0 3.1e-41 141.4 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CAM73045.1 - 0.00059 19.8 0.1 0.0014 18.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CAM73045.1 - 0.00069 19.5 0.2 0.0036 17.2 0.1 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CAM73045.1 - 0.0016 17.5 0.4 0.063 12.3 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 CAM73045.1 - 0.0019 17.2 0.1 0.0035 16.3 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 CAM73045.1 - 0.0082 15.2 0.1 0.18 10.9 0.0 2.7 3 0 0 3 3 3 1 Thi4 family TrkA_N PF02254.13 CAM73045.1 - 0.011 15.7 0.1 0.036 14.0 0.1 1.9 2 0 0 2 2 2 0 TrkA-N domain Mqo PF06039.10 CAM73045.1 - 0.014 13.5 0.0 0.058 11.5 0.0 1.8 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Pyr_redox_3 PF13738.1 CAM73045.1 - 0.022 14.8 0.0 0.055 13.5 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CAM73045.1 - 0.048 14.0 0.1 0.12 12.7 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApoC-I PF04691.7 CAM73048.1 - 0.03 14.0 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) HlyIII PF03006.15 CAM73049.1 - 2e-52 177.7 24.7 2.6e-52 177.4 17.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related NfeD PF01957.13 CAM73049.1 - 5.1 7.2 5.4 0.71 9.9 0.2 2.3 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding HlyIII PF03006.15 CAM73050.1 - 1.6e-49 168.3 27.5 2.3e-49 167.8 19.0 1.2 1 0 0 1 1 1 1 Haemolysin-III related HlyIII PF03006.15 CAM73051.1 - 3.8e-55 186.6 28.5 4.8e-55 186.3 19.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related PCIF1_WW PF12237.3 CAM73052.2 - 5.1e-34 117.0 0.0 2.3e-21 75.8 0.1 2.3 2 0 0 2 2 2 2 Phosphorylated CTD interacting factor 1 WW domain KTI12 PF08433.5 CAM73053.1 - 0.001 18.3 1.1 1.3 8.2 0.0 2.5 2 0 0 2 2 2 2 Chromatin associated protein KTI12 AAA_33 PF13671.1 CAM73053.1 - 0.0018 18.1 1.0 0.0018 18.1 0.7 3.3 2 2 1 3 3 3 1 AAA domain AAA_17 PF13207.1 CAM73053.1 - 0.034 14.9 0.0 0.075 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CAM73053.1 - 0.052 13.3 0.1 0.39 10.4 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain Peptidase_M24 PF00557.19 CAM73055.1 - 2.8e-33 115.2 0.0 4.7e-33 114.5 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 CAM73055.1 - 1.4e-10 40.7 0.0 4.7e-10 38.9 0.0 1.9 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain EMP24_GP25L PF01105.19 CAM73056.1 - 4.7e-11 42.7 0.0 5.6e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF3481 PF11980.3 CAM73056.1 - 0.92 9.3 2.9 0.28 11.0 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3481) HrpB2 PF09487.5 CAM73057.1 - 0.002 18.2 0.0 0.0054 16.9 0.0 1.7 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB2) CAP_C PF08603.6 CAM73058.1 - 3.5e-52 175.9 2.4 4.6e-52 175.5 1.7 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal CAP_N PF01213.14 CAM73058.1 - 3.2e-12 46.3 3.9 4.9e-12 45.7 2.7 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal TBCC PF07986.7 CAM73058.1 - 1.4e-05 24.4 6.8 2.4e-05 23.7 4.7 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C Telomere_Sde2 PF13019.1 CAM73058.1 - 0.63 9.7 3.3 13 5.4 0.0 2.2 2 0 0 2 2 2 0 Telomere stability and silencing NERD PF08378.6 CAM73061.1 - 8e-27 93.7 0.2 1.5e-26 92.9 0.2 1.5 1 0 0 1 1 1 1 Nuclease-related domain tRNA-synt_1 PF00133.17 CAM73062.1 - 3.7e-215 715.4 0.3 3.7e-215 715.4 0.2 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CAM73062.1 - 5.9e-21 74.8 0.1 1.9e-20 73.1 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CAM73062.1 - 1.7e-16 59.8 2.7 9.9e-06 24.4 0.6 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 CAM73062.1 - 0.0045 16.1 0.7 0.11 11.5 0.0 3.0 2 1 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain FAM74 PF15026.1 CAM73063.1 - 0.091 12.4 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 FAM74 protein SWIM PF04434.12 CAM73063.1 - 0.23 10.9 2.8 0.47 9.9 1.9 1.5 1 0 0 1 1 1 0 SWIM zinc finger Cyclin_N PF00134.18 CAM73064.1 - 0.00016 21.2 0.2 0.002 17.6 0.0 2.5 3 0 0 3 3 3 1 Cyclin, N-terminal domain HSA PF07529.8 CAM73065.1 - 0.6 9.9 5.3 0.19 11.5 0.5 2.4 2 0 0 2 2 2 0 HSA DAO PF01266.19 CAM73066.1 - 2.2e-21 76.1 1.7 1.3e-09 37.4 0.3 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CAM73066.1 - 3.9e-08 33.2 0.5 2.4e-07 30.6 0.6 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CAM73066.1 - 7.3e-06 25.9 0.0 0.0002 21.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CAM73066.1 - 1e-05 25.8 1.5 3.4e-05 24.1 0.8 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CAM73066.1 - 3.2e-05 23.1 0.1 6.4e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 CAM73066.1 - 0.00041 20.4 0.5 0.0012 18.8 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CAM73066.1 - 0.00092 18.1 0.5 0.0016 17.3 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 CAM73066.1 - 0.0023 16.8 0.8 0.0038 16.1 0.5 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 CAM73066.1 - 0.012 15.2 0.8 0.027 14.1 0.5 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 CAM73066.1 - 0.023 13.7 0.5 0.047 12.7 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 CAM73066.1 - 0.028 12.8 0.5 0.044 12.2 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 CAM73066.1 - 0.037 12.9 0.0 0.061 12.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_10 PF13460.1 CAM73066.1 - 0.081 12.9 0.6 0.81 9.6 0.3 2.2 2 0 0 2 2 2 0 NADH(P)-binding NAD_binding_9 PF13454.1 CAM73066.1 - 0.095 12.4 0.3 0.25 11.1 0.2 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Shikimate_DH PF01488.15 CAM73066.1 - 0.19 11.8 0.1 0.47 10.5 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase OB_NTP_bind PF07717.11 CAM73067.1 - 3.4e-24 84.8 0.0 7.4e-24 83.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CAM73067.1 - 6.8e-16 58.1 0.4 1.5e-15 57.0 0.3 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CAM73067.1 - 8.4e-12 44.7 0.0 2.1e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAM73067.1 - 2e-10 40.4 0.0 4.1e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CAM73067.1 - 5.5e-05 23.3 0.0 0.00021 21.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 CAM73067.1 - 0.0059 15.5 0.0 0.013 14.3 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 CAM73067.1 - 0.0065 16.4 0.5 0.086 12.8 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain PhoH PF02562.11 CAM73067.1 - 0.0097 15.1 0.1 0.056 12.6 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein Kringle PF00051.13 CAM73067.1 - 0.046 13.8 0.1 0.086 12.9 0.1 1.4 1 0 0 1 1 1 0 Kringle domain AAA_29 PF13555.1 CAM73067.1 - 0.078 12.5 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain KaiC PF06745.8 CAM73067.1 - 0.079 12.0 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 KaiC ResIII PF04851.10 CAM73067.1 - 0.096 12.5 0.1 5.5 6.7 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit CUE PF02845.11 CAM73070.2 - 0.0055 16.1 0.1 0.28 10.7 0.0 3.1 3 0 0 3 3 3 1 CUE domain Cullin_binding PF03556.10 CAM73071.1 - 5.4e-20 71.6 2.3 9.6e-20 70.8 1.6 1.3 1 0 0 1 1 1 1 Cullin binding TruD PF01142.13 CAM73075.1 - 1.2e-46 159.1 0.0 2.7e-39 134.9 0.0 3.7 3 1 0 3 3 3 3 tRNA pseudouridine synthase D (TruD) RAB3GAP2_N PF14655.1 CAM73076.1 - 1.4e-10 40.7 0.1 2.6e-10 39.8 0.1 1.4 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus MS_channel PF00924.13 CAM73077.1 - 1.7e-18 66.7 0.7 2.1e-18 66.4 0.5 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel Gcd10p PF04189.8 CAM73078.1 - 3.4e-72 243.1 0.0 4.5e-72 242.7 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family LRR_4 PF12799.2 CAM73079.1 - 6.7e-06 25.5 0.1 0.0015 18.1 0.0 2.4 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 CAM73079.1 - 3.7e-05 23.3 0.0 5.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 CAM73079.1 - 0.00055 19.6 0.0 0.057 13.1 0.0 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 CAM73079.1 - 0.02 14.8 0.7 0.55 10.4 0.0 3.1 3 0 0 3 3 3 0 Leucine Rich Repeat HMG_box PF00505.14 CAM73084.1 - 0.029 14.6 0.5 0.56 10.5 0.0 3.0 2 1 0 2 2 2 0 HMG (high mobility group) box GAGA_bind PF06217.7 CAM73084.1 - 0.32 10.9 7.5 0.15 11.9 3.7 1.4 1 1 0 1 1 1 0 GAGA binding protein-like family HMG_box_2 PF09011.5 CAM73085.1 - 3.9e-05 23.9 3.6 0.011 16.0 0.1 2.4 2 1 0 2 2 2 2 HMG-box domain YABBY PF04690.8 CAM73085.1 - 0.0025 18.0 0.4 0.0029 17.8 0.3 1.1 1 0 0 1 1 1 1 YABBY protein DUF3106 PF11304.3 CAM73085.1 - 0.0095 16.3 1.2 0.017 15.5 0.6 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF3106) HMG_box PF00505.14 CAM73085.1 - 0.065 13.5 4.6 0.16 12.2 0.3 2.9 2 2 0 2 2 2 0 HMG (high mobility group) box TP53IP5 PF15331.1 CAM73086.1 - 0.085 12.7 0.2 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 AAA PF00004.24 CAM73087.1 - 2e-11 44.2 0.0 7e-05 23.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CAM73087.1 - 3.2e-05 23.6 0.0 6.3e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CAM73087.1 - 0.0012 18.8 2.2 0.0023 17.9 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 CAM73087.1 - 0.0017 17.3 0.0 0.0034 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 CAM73087.1 - 0.035 14.0 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CAM73087.1 - 0.039 14.0 0.0 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.7 CAM73089.1 - 1.9e-67 226.7 0.4 2.7e-67 226.2 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CAM73089.1 - 1.4e-06 28.2 0.0 2.9e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 CAM73089.1 - 8.4e-06 25.1 0.0 1.6e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family YliH PF10799.3 CAM73089.1 - 0.0017 18.0 0.2 0.005 16.5 0.1 1.8 1 0 0 1 1 1 1 Biofilm formation protein (YliH/bssR) Miro PF08477.8 CAM73089.1 - 0.0019 18.6 0.0 0.011 16.2 0.0 2.1 2 1 0 2 2 2 1 Miro-like protein ATP_bind_1 PF03029.12 CAM73089.1 - 0.0052 16.3 0.6 0.0094 15.5 0.1 1.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Ras PF00071.17 CAM73089.1 - 0.006 15.9 0.0 0.0089 15.4 0.0 1.3 1 0 0 1 1 1 1 Ras family DUF910 PF06014.6 CAM73089.1 - 0.0083 16.0 0.1 0.042 13.7 0.0 2.2 3 0 0 3 3 3 1 Bacterial protein of unknown function (DUF910) SRPRB PF09439.5 CAM73089.1 - 0.011 14.9 0.0 0.024 13.8 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RPAP3_C PF13877.1 CAM73089.1 - 0.067 13.1 1.7 0.14 12.1 1.2 1.5 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 Pro-rich_19 PF15455.1 CAM73089.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Proline-rich 19 CDP-OH_P_transf PF01066.16 CAM73091.1 - 5.9e-18 65.0 2.4 5.9e-18 65.0 1.6 3.0 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase HAD_2 PF13419.1 CAM73092.1 - 2.8e-09 37.4 0.1 1.7e-08 34.8 0.1 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CAM73092.1 - 0.0087 16.4 0.1 0.014 15.8 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Taxilin PF09728.4 CAM73094.1 - 0.00088 18.4 53.2 0.0011 18.1 36.9 1.0 1 0 0 1 1 1 1 Myosin-like coiled-coil protein NPV_P10 PF05531.7 CAM73094.1 - 2.1 8.6 17.2 4.3 7.6 0.0 4.3 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein LmjF365940-deam PF14421.1 CAM73095.1 - 6e-45 153.0 0.1 5.7e-24 84.5 0.0 2.3 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases dCMP_cyt_deam_1 PF00383.17 CAM73095.1 - 0.049 13.2 0.1 0.081 12.5 0.0 1.4 1 1 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region GDPD PF03009.12 CAM73097.1 - 6.6e-25 88.0 0.2 1.3e-24 87.0 0.1 1.6 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family PI-PLC-X PF00388.14 CAM73097.1 - 0.0086 15.4 0.1 0.017 14.5 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Tmemb_185A PF10269.4 CAM73098.1 - 0.045 13.3 23.6 0.16 11.5 11.4 3.1 1 1 1 2 2 2 0 Transmembrane Fragile-X-F protein DUF2207 PF09972.4 CAM73098.1 - 0.12 10.9 4.6 5.4 5.4 1.5 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) NfeD PF01957.13 CAM73098.1 - 1.8 8.7 6.6 22 5.1 0.0 2.5 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding ICMT PF04140.9 CAM73098.1 - 1.9 8.7 9.1 1.5 9.1 0.8 3.0 2 1 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family RRM_1 PF00076.17 CAM73099.1 - 0.025 14.2 0.0 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SpoV PF08183.6 CAM73100.2 - 4.9e-10 38.8 0.0 8.5e-10 38.1 0.0 1.4 1 0 0 1 1 1 1 Stage V sporulation protein family TMF_DNA_bd PF12329.3 CAM73102.1 - 0.0013 18.4 7.6 0.0013 18.4 5.3 3.6 4 0 0 4 4 4 1 TATA element modulatory factor 1 DNA binding Baculo_PEP_C PF04513.7 CAM73102.1 - 0.066 13.0 4.7 0.62 9.8 0.3 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.16 CAM73102.1 - 0.81 9.0 35.2 0.48 9.8 7.8 3.1 1 1 1 2 2 2 0 Intermediate filament protein TMF_TATA_bd PF12325.3 CAM73102.1 - 2.4 7.9 25.5 0.13 11.9 1.2 3.7 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding V_ATPase_I PF01496.14 CAM73102.1 - 4.2 5.0 13.3 6.1 4.5 9.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rho_Binding PF08912.6 CAM73102.1 - 5.6 7.3 15.1 7.2 6.9 0.7 3.8 2 2 1 3 3 3 0 Rho Binding OTU PF02338.14 CAM73103.1 - 2.2e-11 44.4 0.0 2e-10 41.3 0.0 2.4 2 1 0 2 2 2 1 OTU-like cysteine protease COG2 PF06148.6 CAM73105.1 - 1.5e-42 144.5 0.0 4.4e-42 143.0 0.0 1.9 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.3 CAM73105.1 - 3.9e-19 68.9 0.1 1.9e-18 66.7 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3510) MIF4G PF02854.14 CAM73107.1 - 3e-23 82.3 0.0 6.5e-23 81.2 0.0 1.6 1 0 0 1 1 1 1 MIF4G domain Ebp2 PF05890.7 CAM73107.1 - 0.19 11.0 1.5 0.45 9.7 0.1 2.0 1 1 1 2 2 2 0 Eukaryotic rRNA processing protein EBP2 RabGAP-TBC PF00566.13 CAM73108.1 - 2.9e-56 190.3 0.0 3.7e-56 189.9 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RabGAP-TBC PF00566.13 CAM73109.1 - 5.9e-60 202.3 0.3 7.9e-60 201.9 0.2 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ABC1 PF03109.11 CAM73110.1 - 2.9e-28 98.2 0.0 5.9e-28 97.2 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Pkinase_Tyr PF07714.12 CAM73110.1 - 1e-06 28.0 0.0 0.0047 16.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 CAM73110.1 - 1.3e-06 27.7 0.4 0.047 12.8 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.18 CAM73110.1 - 3.2e-05 23.7 0.0 7.1e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 CAM73110.1 - 0.00055 19.3 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 RIO1 family NanE PF04131.9 CAM73110.1 - 0.086 11.7 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase TPR_19 PF14559.1 CAM73111.1 - 0.0018 18.5 14.7 2.7 8.3 0.1 5.2 4 1 2 6 6 6 3 Tetratricopeptide repeat PPR_3 PF13812.1 CAM73111.1 - 0.0047 17.1 6.6 6.8 7.2 0.1 5.3 5 0 0 5 5 5 1 Pentatricopeptide repeat domain Apc3 PF12895.2 CAM73111.1 - 0.0068 16.5 16.8 0.79 9.8 0.2 5.2 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 CAM73111.1 - 0.0078 16.8 25.7 0.5 11.1 2.7 5.7 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 CAM73111.1 - 0.014 15.3 14.6 6 7.0 0.1 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat AATase PF07247.7 CAM73111.1 - 0.04 12.4 0.1 0.067 11.7 0.0 1.3 1 0 0 1 1 1 0 Alcohol acetyltransferase TPR_14 PF13428.1 CAM73111.1 - 0.052 14.2 22.8 1.1 10.1 0.2 6.2 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 CAM73111.1 - 0.41 10.5 2.6 3.3 7.7 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat EF-hand_7 PF13499.1 CAM73112.1 - 7.3e-13 48.4 0.7 5.8e-05 23.1 0.0 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CAM73112.1 - 2.6e-10 39.7 0.9 5e-05 22.8 0.3 3.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 CAM73112.1 - 4.9e-10 38.4 4.9 0.0035 17.1 0.0 4.6 3 1 2 5 5 5 3 EF-hand domain EF-hand_1 PF00036.27 CAM73112.1 - 1.3e-08 33.5 1.5 0.011 15.0 0.0 4.7 4 1 0 4 4 4 2 EF hand EF-hand_9 PF14658.1 CAM73112.1 - 4.9e-06 26.3 0.0 0.0061 16.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 CAM73112.1 - 0.0041 16.4 0.4 3 7.3 0.1 3.6 3 0 0 3 3 3 1 EF hand DUF3435 PF11917.3 CAM73112.1 - 0.071 11.8 0.0 0.086 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) Fis1_TPR_C PF14853.1 CAM73116.1 - 1.3e-05 25.0 1.4 2.9e-05 23.8 0.5 2.0 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.1 CAM73116.1 - 0.0029 17.2 0.2 0.0071 15.9 0.1 1.7 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 CAM73116.1 - 0.0038 16.7 0.1 0.008 15.7 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 CAM73116.1 - 0.026 14.4 0.0 0.089 12.7 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Ran_BP1 PF00638.13 CAM73117.1 - 0.0092 16.0 0.0 0.02 14.9 0.0 1.5 1 1 0 1 1 1 1 RanBP1 domain Kelch_5 PF13854.1 CAM73118.1 - 8.1e-16 57.5 1.5 0.0092 15.9 0.0 5.7 7 0 0 7 7 7 4 Kelch motif Kelch_3 PF13415.1 CAM73118.1 - 7e-14 51.5 13.6 0.00016 21.6 0.0 6.1 5 2 1 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.1 CAM73118.1 - 1.3e-13 50.4 3.5 0.00078 19.1 0.0 5.1 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.20 CAM73118.1 - 9.7e-12 44.2 0.0 0.018 14.5 0.0 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.1 CAM73118.1 - 3.9e-06 26.7 0.9 4.4 7.6 0.0 5.1 5 1 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 CAM73118.1 - 1.6e-05 24.4 0.0 0.46 10.3 0.0 4.8 5 0 0 5 5 5 1 Kelch motif Suc_Fer-like PF06999.7 CAM73119.1 - 1.8e-25 90.3 0.5 5.7e-25 88.6 0.1 1.7 1 1 1 2 2 2 1 Sucrase/ferredoxin-like Vps54 PF07928.7 CAM73122.1 - 1.5e-33 115.7 5.0 9.3e-31 106.7 0.1 4.1 4 0 0 4 4 4 2 Vps54-like protein GCN5L1 PF06320.8 CAM73122.1 - 0.011 15.5 0.0 0.06 13.1 0.0 2.2 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) AAA_13 PF13166.1 CAM73123.2 - 1.2 7.4 9.4 2.2 6.6 6.5 1.3 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 CAM73124.1 - 1.2e-60 203.7 0.0 1.3e-60 203.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CAM73124.1 - 4.9e-13 48.7 0.0 5.8e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CAM73124.1 - 4.5e-12 46.5 0.0 6.2e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 CAM73124.1 - 9.8e-12 44.5 0.0 1.1e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 CAM73124.1 - 4.2e-11 42.8 0.0 6e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 CAM73124.1 - 7.6e-11 41.3 0.0 2.4e-08 33.0 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 CAM73124.1 - 7.5e-10 38.3 0.0 8.6e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 CAM73124.1 - 2.4e-05 23.8 0.0 0.00013 21.4 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 CAM73124.1 - 0.0059 16.1 0.1 0.02 14.3 0.1 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 CAM73124.1 - 0.01 15.1 0.2 0.16 11.2 0.1 2.3 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_17 PF13207.1 CAM73124.1 - 0.011 16.5 0.5 0.66 10.8 0.3 2.2 1 1 0 1 1 1 0 AAA domain ArgK PF03308.11 CAM73124.1 - 0.013 14.2 0.1 0.18 10.5 0.1 2.2 1 1 0 1 1 1 0 ArgK protein Dynamin_N PF00350.18 CAM73124.1 - 0.016 15.0 0.0 1.6 8.5 0.0 2.1 2 0 0 2 2 2 0 Dynamin family DSBA PF01323.15 CAM73124.1 - 0.034 13.7 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 DSBA-like thioredoxin domain AAA_18 PF13238.1 CAM73124.1 - 0.053 13.8 0.0 0.079 13.2 0.0 1.3 1 1 0 1 1 1 0 AAA domain CdhD PF03599.11 CAM73124.1 - 0.056 11.9 0.0 0.077 11.4 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit Thioredoxin_2 PF13098.1 CAM73124.1 - 0.092 12.9 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain AAA_28 PF13521.1 CAM73125.1 - 0.0016 18.3 0.1 0.0036 17.2 0.1 1.6 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 CAM73125.1 - 0.14 12.6 0.0 0.72 10.3 0.0 2.1 1 1 0 1 1 1 0 Miro-like protein AAA_14 PF13173.1 CAM73125.1 - 0.16 11.8 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.4 CAM73125.1 - 0.22 10.4 0.1 0.42 9.4 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 FAT PF02259.18 CAM73126.1 - 2.2e-55 188.0 0.4 4.2e-55 187.1 0.3 1.5 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 CAM73126.1 - 2.1e-53 181.2 0.1 4.2e-53 180.2 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 CAM73126.1 - 1.8e-35 122.2 0.4 1.1e-33 116.3 0.0 4.1 6 0 0 6 6 6 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 CAM73126.1 - 6e-29 100.0 0.3 2.6e-28 98.0 0.2 2.2 1 0 0 1 1 1 1 Rapamycin binding domain FATC PF02260.15 CAM73126.1 - 2.4e-16 58.8 0.1 2.4e-16 58.8 0.1 1.9 2 0 0 2 2 2 1 FATC domain HEAT_EZ PF13513.1 CAM73126.1 - 3.9 8.0 20.7 37 4.9 0.0 9.4 11 1 1 12 12 12 0 HEAT-like repeat S-methyl_trans PF02574.11 CAM73127.2 - 3.4e-29 102.1 0.0 4.4e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase AAA PF00004.24 CAM73128.1 - 4.5e-44 149.8 0.0 1e-43 148.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CAM73128.1 - 6.4e-08 32.4 0.1 2.4e-07 30.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CAM73128.1 - 7.7e-07 29.1 0.0 2e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CAM73128.1 - 1.4e-06 28.4 0.3 2.8e-05 24.2 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CAM73128.1 - 4.4e-06 26.8 1.1 0.00031 20.9 0.2 3.0 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CAM73128.1 - 1.5e-05 24.6 1.5 0.00038 20.1 0.2 2.8 2 1 0 2 2 2 1 Part of AAA domain RuvB_N PF05496.7 CAM73128.1 - 2.5e-05 23.4 0.0 5.8e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 CAM73128.1 - 6.7e-05 23.6 0.1 0.00028 21.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CAM73128.1 - 0.00018 20.9 0.0 0.00049 19.5 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 CAM73128.1 - 0.00062 19.6 0.0 0.0028 17.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CAM73128.1 - 0.0014 18.5 0.1 0.0035 17.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 CAM73128.1 - 0.0017 17.8 0.6 0.14 11.5 0.0 2.8 2 1 1 3 3 3 1 AAA domain Zeta_toxin PF06414.7 CAM73128.1 - 0.0022 17.1 0.1 0.0054 15.8 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin KaiC PF06745.8 CAM73128.1 - 0.0024 17.0 0.2 0.084 11.9 0.0 2.6 3 0 0 3 3 3 1 KaiC NB-ARC PF00931.17 CAM73128.1 - 0.0025 16.7 0.0 0.055 12.3 0.0 2.3 1 1 1 2 2 2 1 NB-ARC domain AAA_28 PF13521.1 CAM73128.1 - 0.0032 17.4 0.2 0.0071 16.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.8 CAM73128.1 - 0.0032 16.2 0.0 0.011 14.5 0.0 1.8 2 0 0 2 2 2 1 TIP49 C-terminus AAA_18 PF13238.1 CAM73128.1 - 0.0042 17.4 0.2 0.024 14.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.6 CAM73128.1 - 0.0058 16.2 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CAM73128.1 - 0.0063 15.9 0.9 0.051 13.0 0.0 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 CAM73128.1 - 0.0068 15.5 0.0 0.023 13.8 0.0 1.8 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 CAM73128.1 - 0.0071 16.3 0.1 0.13 12.3 0.0 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain RNA_helicase PF00910.17 CAM73128.1 - 0.01 15.9 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 CAM73128.1 - 0.011 15.3 0.1 0.033 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 CAM73128.1 - 0.016 14.4 0.1 0.062 12.5 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein DUF815 PF05673.8 CAM73128.1 - 0.022 13.6 0.2 0.048 12.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Parvo_NS1 PF01057.12 CAM73128.1 - 0.04 12.7 0.0 0.07 11.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.7 CAM73128.1 - 0.043 13.4 0.0 0.59 9.7 0.0 2.3 1 1 0 2 2 2 0 NACHT domain ADIP PF11559.3 CAM73128.1 - 0.051 13.4 2.2 0.1 12.5 1.5 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DASH_Dad2 PF08654.5 CAM73128.1 - 0.069 13.1 0.5 0.19 11.7 0.3 1.7 1 0 0 1 1 1 0 DASH complex subunit Dad2 DUF2968 PF11180.3 CAM73128.1 - 0.22 10.8 1.8 0.48 9.7 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) C2 PF00168.25 CAM73131.1 - 3.8e-08 33.0 0.0 0.37 10.6 0.0 4.5 4 0 0 4 4 4 4 C2 domain C2 PF00168.25 CAM73132.1 - 1.1e-31 108.4 0.1 1.3e-09 37.7 0.0 5.4 6 0 0 6 6 6 4 C2 domain CEP76-C2 PF15627.1 CAM73132.1 - 0.003 17.0 0.2 0.31 10.5 0.0 2.7 2 0 0 2 2 2 2 CEP76 C2 domain SET PF00856.23 CAM73133.1 - 8.8e-10 39.1 0.0 4.6e-09 36.7 0.0 2.0 1 1 0 1 1 1 1 SET domain DUF3618 PF12277.3 CAM73133.1 - 1.2 9.2 4.4 20 5.3 2.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) CHAP PF05257.11 CAM73134.1 - 5.8e-14 51.8 0.2 1.2e-13 50.7 0.2 1.5 1 0 0 1 1 1 1 CHAP domain Arf PF00025.16 CAM73135.1 - 2.9e-11 42.8 0.0 5.3e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family PH PF00169.24 CAM73135.1 - 0.00099 19.2 0.0 0.0021 18.2 0.0 1.5 1 0 0 1 1 1 1 PH domain MMR_HSR1 PF01926.18 CAM73135.1 - 0.0093 15.9 0.0 0.036 14.0 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase PH_8 PF15409.1 CAM73135.1 - 0.031 14.3 0.2 0.12 12.5 0.1 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain TPR_14 PF13428.1 CAM73136.1 - 2e-07 31.0 51.9 0.022 15.3 0.7 12.0 9 3 4 13 13 13 6 Tetratricopeptide repeat TPR_19 PF14559.1 CAM73136.1 - 2.5e-07 30.9 7.5 0.03 14.6 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat HAT PF02184.11 CAM73136.1 - 1.2e-06 28.1 16.9 0.09 12.5 0.2 5.7 6 0 0 6 6 6 3 HAT (Half-A-TPR) repeat NRDE-2 PF08424.5 CAM73136.1 - 9.8e-05 21.3 5.2 0.0016 17.3 0.2 3.3 3 1 0 3 3 3 2 NRDE-2, necessary for RNA interference TPR_16 PF13432.1 CAM73136.1 - 0.018 15.7 44.1 1.3 9.7 2.8 8.2 7 2 1 8 8 8 0 Tetratricopeptide repeat DUF2063 PF09836.4 CAM73136.1 - 0.025 14.5 0.7 0.1 12.5 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2063) Pyridoxal_deC PF00282.14 CAM73136.1 - 0.081 11.3 0.0 0.18 10.2 0.0 1.5 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain CCP_MauG PF03150.9 CAM73136.1 - 0.32 11.2 0.0 0.32 11.2 0.0 3.0 3 2 1 4 4 4 0 Di-haem cytochrome c peroxidase TPR_17 PF13431.1 CAM73136.1 - 0.9 9.8 4.8 31 5.1 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 CAM73136.1 - 7.9 6.5 14.4 8.4 6.4 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat Pkinase PF00069.20 CAM73139.2 - 3.1e-46 157.6 0.0 8.7e-23 80.7 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAM73139.2 - 1.3e-18 66.9 0.0 9e-12 44.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CAM73139.2 - 0.16 10.8 0.0 2.1 7.2 0.0 2.2 2 0 0 2 2 2 0 Kinase-like LRR_6 PF13516.1 CAM73141.1 - 1.3e-43 142.1 33.3 0.01 15.8 0.0 20.0 19 1 0 19 19 19 12 Leucine Rich repeat LRR_4 PF12799.2 CAM73141.1 - 7.4e-28 95.6 24.2 8.5e-05 22.0 0.0 12.9 8 4 6 15 15 15 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CAM73141.1 - 6.3e-11 40.7 17.4 14 6.1 0.1 15.0 17 2 0 17 17 17 3 Leucine Rich Repeat LRR_7 PF13504.1 CAM73141.1 - 1.1e-08 33.8 4.9 20 5.9 0.0 10.8 13 0 0 13 13 13 1 Leucine rich repeat LRR_8 PF13855.1 CAM73141.1 - 3e-08 33.3 32.8 0.0016 18.1 0.1 11.7 10 4 4 14 14 14 4 Leucine rich repeat WD40 PF00400.27 CAM73143.1 - 6.5e-23 79.7 6.2 1.6e-07 30.9 0.0 8.6 9 0 0 9 9 9 4 WD domain, G-beta repeat Utp21 PF04192.7 CAM73143.1 - 6.4e-18 64.7 0.1 9.8e-18 64.1 0.0 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain PQQ_2 PF13360.1 CAM73143.1 - 1.2e-05 24.9 4.6 0.0037 16.7 0.5 3.1 2 2 0 2 2 2 2 PQQ-like domain Nup160 PF11715.3 CAM73143.1 - 4.6e-05 21.7 3.0 0.0074 14.4 0.0 4.3 4 1 0 4 4 4 1 Nucleoporin Nup120/160 Utp12 PF04003.7 CAM73143.1 - 0.058 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Dip2/Utp12 Family Arrestin_N PF00339.24 CAM73144.1 - 2.5e-07 30.6 0.0 1.8e-05 24.5 0.0 3.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 CAM73144.1 - 8.3e-06 25.4 0.0 3.7e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Arrestin_N terminal like Sld5 PF05916.6 CAM73145.1 - 1.6e-23 83.0 0.0 2.4e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Glycos_transf_4 PF00953.16 CAM73146.1 - 6e-45 152.8 4.7 6e-45 152.8 3.3 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 4 Seadorna_Vp10 PF07322.6 CAM73146.1 - 0.12 11.6 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus Vp10 DUF2929 PF11151.3 CAM73146.1 - 2.7 8.1 6.2 0.7 10.0 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2929) ADH_zinc_N PF00107.21 CAM73147.1 - 1.7e-35 121.3 0.0 3.4e-35 120.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CAM73147.1 - 3.5e-15 57.0 0.0 9.1e-15 55.6 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CAM73147.1 - 6.5e-14 51.6 0.0 2.1e-13 49.9 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.19 CAM73147.1 - 0.023 15.0 0.1 0.64 10.3 0.0 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Cpn10 PF00166.16 CAM73147.1 - 0.076 12.9 0.4 1.3 8.9 0.0 2.6 3 0 0 3 3 3 0 Chaperonin 10 Kd subunit TrkA_N PF02254.13 CAM73147.1 - 0.092 12.7 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain CorA PF01544.13 CAM73149.1 - 0.39 9.6 3.5 1 8.3 2.4 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein TFIIS_C PF01096.13 CAM73150.1 - 8.3e-11 41.3 8.4 8.3e-11 41.3 5.8 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DUF1451 PF07295.6 CAM73150.1 - 0.0044 16.7 0.7 0.0044 16.7 0.5 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1451) TCP PF03634.8 CAM73150.1 - 0.036 14.4 0.2 0.055 13.8 0.1 1.2 1 0 0 1 1 1 0 TCP family transcription factor Trm112p PF03966.11 CAM73150.1 - 0.057 13.7 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Trm112p-like protein Sar8_2 PF03058.9 CAM73150.1 - 0.089 13.1 0.3 0.089 13.1 0.2 2.3 2 1 0 2 2 2 0 Sar8.2 family Ribosomal_L40e PF01020.12 CAM73150.1 - 0.85 9.2 4.6 16 5.1 0.2 2.5 2 0 0 2 2 2 0 Ribosomal L40e family zf-ribbon_3 PF13248.1 CAM73150.1 - 1.1 8.5 8.1 9 5.6 0.0 3.7 4 0 0 4 4 4 0 zinc-ribbon domain HypA PF01155.14 CAM73150.1 - 3.6 7.3 9.4 1.2 8.8 0.7 2.5 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_5 PF13719.1 CAM73150.1 - 6.9 6.3 8.0 10 5.8 0.9 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Baculo_LEF5_C PF11792.3 CAM73150.1 - 9.9 5.6 9.0 1.1 8.6 2.7 2.1 2 1 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain Amastin PF07344.6 CAM73151.1 - 1.2e-14 54.1 6.3 2e-14 53.4 4.3 1.4 1 1 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.15 CAM73151.1 - 0.049 13.2 7.5 0.13 11.8 5.2 1.8 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family SecY PF00344.15 CAM73151.1 - 0.37 9.6 5.8 0.54 9.1 4.0 1.3 1 0 0 1 1 1 0 SecY translocase Claudin_2 PF13903.1 CAM73151.1 - 0.55 9.8 12.9 1.4 8.5 8.4 2.0 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction SUR7 PF06687.7 CAM73151.1 - 2 7.9 18.3 53 3.2 12.0 2.6 1 1 0 1 1 1 0 SUR7/PalI family DUF4199 PF13858.1 CAM73151.1 - 9.6 6.1 8.7 1.6 8.6 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) Amastin PF07344.6 CAM73152.1 - 4.2e-07 29.6 4.8 4.2e-07 29.6 3.3 2.0 2 0 0 2 2 2 1 Amastin surface glycoprotein Glyco_hydro_31 PF01055.21 CAM73155.1 - 2.4e-48 165.0 0.0 2.5e-32 112.3 0.0 2.7 2 1 0 2 2 2 2 Glycosyl hydrolases family 31 DUF3947 PF13135.1 CAM73156.1 - 0.095 12.9 0.4 11 6.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3947) IQ PF00612.22 CAM73157.1 - 1.1e-10 40.1 16.9 0.00041 19.7 0.1 4.2 4 0 0 4 4 4 3 IQ calmodulin-binding motif Macoilin PF09726.4 CBZ08303.1 - 0.047 11.9 3.7 0.066 11.5 2.5 1.2 1 0 0 1 1 1 0 Transmembrane protein HR1 PF02185.11 CBZ08303.1 - 0.073 12.8 0.8 0.26 11.0 0.5 2.0 1 0 0 1 1 1 0 Hr1 repeat GrpE PF01025.14 CBZ08303.1 - 0.39 10.2 3.1 2.3 7.7 0.8 2.4 2 0 0 2 2 2 0 GrpE Macoilin PF09726.4 CBZ08304.1 - 0.047 11.9 3.7 0.066 11.5 2.5 1.2 1 0 0 1 1 1 0 Transmembrane protein HR1 PF02185.11 CBZ08304.1 - 0.073 12.8 0.8 0.26 11.0 0.5 2.0 1 0 0 1 1 1 0 Hr1 repeat GrpE PF01025.14 CBZ08304.1 - 0.39 10.2 3.1 2.3 7.7 0.8 2.4 2 0 0 2 2 2 0 GrpE LRR_4 PF12799.2 CBZ08305.1 - 1.4e-66 219.2 0.0 0.0011 18.5 0.0 17.7 8 4 6 18 18 18 17 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ08305.1 - 2.2e-21 75.3 11.9 0.034 13.8 0.1 11.5 8 2 4 12 12 12 8 Leucine rich repeat LRR_1 PF00560.28 CBZ08305.1 - 3.9e-20 68.7 19.8 0.42 10.8 0.1 22.5 29 0 0 29 29 29 3 Leucine Rich Repeat LRR_7 PF13504.1 CBZ08305.1 - 3.1e-08 32.4 14.0 0.48 10.8 0.1 13.5 15 0 0 15 15 15 1 Leucine rich repeat LRR_6 PF13516.1 CBZ08305.1 - 9.5e-07 28.2 8.0 29 5.1 0.0 12.4 15 1 1 16 16 16 0 Leucine Rich repeat LRR_5 PF13306.1 CBZ08305.1 - 0.00026 20.7 0.5 2.5 7.8 0.0 5.4 4 2 2 6 6 6 1 Leucine rich repeats (6 copies) HJURP_mid PF12346.3 CBZ08305.1 - 0.047 13.8 0.1 21 5.2 0.0 3.4 2 1 1 3 3 3 0 Holliday junction recognition protein-associated repeat zf-RING_2 PF13639.1 CBZ08305.1 - 3.4 7.5 19.0 17 5.3 13.2 2.4 1 0 0 1 1 1 0 Ring finger domain 2-Hacid_dh_C PF02826.14 CBZ08307.1 - 2.5e-54 183.1 0.0 3.8e-54 182.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CBZ08307.1 - 1.6e-32 111.7 0.1 2.1e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CBZ08307.1 - 4.9e-06 26.4 0.3 1.2e-05 25.2 0.2 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.20 CBZ08307.1 - 0.00075 18.9 0.2 0.011 15.1 0.0 2.8 3 0 0 3 3 3 1 ACT domain AdoHcyase_NAD PF00670.16 CBZ08307.1 - 0.006 16.4 0.4 0.011 15.5 0.3 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 CBZ08307.1 - 0.026 13.8 0.1 0.049 12.9 0.0 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain XdhC_C PF13478.1 CBZ08307.1 - 0.052 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain Aminotran_5 PF00266.14 CBZ08308.1 - 6.9e-19 67.8 0.0 8.2e-19 67.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Met_10 PF02475.11 CBZ08309.1 - 1.7e-41 142.0 0.0 5.8e-38 130.5 0.0 2.1 2 0 0 2 2 2 2 Met-10+ like-protein Methyltransf_26 PF13659.1 CBZ08309.1 - 8.6e-08 32.2 0.1 4.6e-07 29.8 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ08309.1 - 5.4e-06 26.9 0.0 9.7e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBZ08309.1 - 5.2e-05 22.6 0.0 0.00011 21.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.5 CBZ08309.1 - 0.00012 21.6 0.0 0.00022 20.8 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.1 CBZ08309.1 - 0.00016 21.2 0.0 0.00032 20.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 CBZ08309.1 - 0.0068 15.1 0.0 0.012 14.3 0.0 1.3 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase DNA_methylase PF00145.12 CBZ08309.1 - 0.07 12.2 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase Acyltransferase PF01553.16 CBZ08311.1 - 8.9e-14 51.0 0.0 3.9e-13 48.9 0.0 2.0 1 1 0 1 1 1 1 Acyltransferase DNA_primase_lrg PF04104.9 CBZ08312.1 - 5.9e-77 258.4 0.0 8.6e-77 257.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit FAM220 PF15487.1 CBZ08312.1 - 0.0022 17.4 0.1 0.031 13.6 0.0 2.2 2 0 0 2 2 2 1 FAM220 family CtaG_Cox11 PF04442.9 CBZ08313.1 - 1.4e-41 141.7 0.0 1.6e-41 141.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 CH PF00307.26 CBZ08314.1 - 0.059 13.4 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Calponin homology (CH) domain Sec2p PF06428.6 CBZ08314.1 - 0.06 13.2 5.6 0.2 11.5 0.0 3.4 3 0 0 3 3 3 0 GDP/GTP exchange factor Sec2p Vir_act_alpha_C PF10400.4 CBZ08314.1 - 7 7.0 13.5 5 7.5 1.9 4.1 2 1 1 3 3 3 0 Virulence activator alpha C-term LRR_4 PF12799.2 CBZ08315.1 - 5.3e-17 61.0 12.4 6e-06 25.7 0.8 4.7 3 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ08315.1 - 5.2e-11 42.1 13.5 0.00022 20.9 1.4 3.8 4 0 0 4 4 4 3 Leucine rich repeat LRR_9 PF14580.1 CBZ08315.1 - 1e-06 28.4 2.5 0.00048 19.7 0.6 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.28 CBZ08315.1 - 7.4e-05 22.2 15.1 0.79 9.9 0.1 6.7 5 2 1 6 6 6 2 Leucine Rich Repeat LRR_7 PF13504.1 CBZ08315.1 - 0.00074 19.3 14.1 0.33 11.3 0.0 6.6 7 0 0 7 7 7 2 Leucine rich repeat DUF4530 PF15039.1 CBZ08315.1 - 0.0048 16.7 1.3 0.032 14.1 0.9 2.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4530) LRR_6 PF13516.1 CBZ08315.1 - 0.013 15.4 8.8 12 6.3 0.0 5.8 5 1 1 6 6 6 0 Leucine Rich repeat Mnd1 PF03962.10 CBZ08315.1 - 2.3 7.8 6.0 5 6.7 4.1 1.5 1 0 0 1 1 1 0 Mnd1 family GAS PF13851.1 CBZ08315.1 - 3.4 6.8 7.6 6 6.0 5.3 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Acetyltransf_1 PF00583.19 CBZ08316.1 - 8.3e-10 38.5 0.0 1.2e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBZ08316.1 - 2.5e-06 27.5 0.1 4.8e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CBZ08316.1 - 0.00014 21.7 0.0 0.00023 20.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4257 PF14074.1 CBZ08316.1 - 0.028 14.0 0.0 0.097 12.3 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4257) DUF4558 PF15104.1 CBZ08317.1 - 2.3e-05 24.2 3.1 2.8e-05 23.9 2.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4558) Ank_2 PF12796.2 CBZ08321.1 - 9.9e-53 176.4 0.0 4e-17 62.3 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 CBZ08321.1 - 8.3e-34 113.7 3.0 2e-08 33.6 0.0 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 CBZ08321.1 - 1.1e-30 105.3 6.6 6.7e-10 39.2 0.0 5.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBZ08321.1 - 3e-29 100.3 7.1 2.2e-10 40.4 0.0 5.8 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ08321.1 - 1.2e-21 74.5 3.1 0.00026 20.9 0.0 6.5 7 0 0 7 7 7 4 Ankyrin repeat zf-DHHC PF01529.15 CBZ08321.1 - 8.2e-06 25.3 0.0 2.6e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 DHHC palmitoyltransferase PHO4 PF01384.15 CBZ08323.1 - 2.5e-103 345.1 17.4 3.3e-103 344.7 12.1 1.2 1 0 0 1 1 1 1 Phosphate transporter family DSPc PF00782.15 CBZ08324.1 - 0.033 13.7 0.4 0.069 12.7 0.3 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain RRM_1 PF00076.17 CBZ08325.1 - 5.7e-13 48.2 0.7 0.00011 21.7 0.0 5.4 5 1 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ08325.1 - 1.3e-06 28.3 0.1 0.14 12.1 0.0 5.3 6 0 0 6 6 6 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ08325.1 - 0.00056 19.7 0.0 0.71 9.7 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TruD PF01142.13 CBZ08326.1 - 0.071 11.7 0.0 0.13 10.8 0.0 1.4 1 0 0 1 1 1 0 tRNA pseudouridine synthase D (TruD) AAA PF00004.24 CBZ08327.1 - 6.5e-45 152.5 0.0 1.2e-44 151.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CBZ08327.1 - 9.2e-08 32.1 0.0 2.4e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CBZ08327.1 - 8.4e-07 28.7 0.1 7.3e-06 25.7 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CBZ08327.1 - 1.7e-06 27.5 0.3 0.00031 20.2 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 CBZ08327.1 - 2.2e-06 27.8 0.1 0.0046 17.1 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 CBZ08327.1 - 2.2e-06 27.7 0.0 0.00022 21.2 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 CBZ08327.1 - 6.3e-06 25.4 0.0 1.7e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CBZ08327.1 - 0.00013 21.6 0.1 0.00027 20.6 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain DUF815 PF05673.8 CBZ08327.1 - 0.00021 20.3 0.0 0.00046 19.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 CBZ08327.1 - 0.0007 19.5 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 CBZ08327.1 - 0.00084 18.1 0.0 0.0017 17.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 CBZ08327.1 - 0.0012 18.3 0.8 0.0021 17.5 0.1 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.1 CBZ08327.1 - 0.0014 19.4 1.0 0.003 18.3 0.1 2.0 2 1 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 CBZ08327.1 - 0.0014 18.7 0.0 0.0044 17.1 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 CBZ08327.1 - 0.0014 18.9 0.2 0.006 16.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CBZ08327.1 - 0.0017 17.5 0.0 0.0032 16.6 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.12 CBZ08327.1 - 0.0045 15.8 0.0 0.008 15.0 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_24 PF13479.1 CBZ08327.1 - 0.01 15.3 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CBZ08327.1 - 0.013 15.8 0.1 0.092 13.0 0.0 2.3 2 0 0 2 2 2 0 ABC transporter Arch_ATPase PF01637.13 CBZ08327.1 - 0.013 15.1 1.2 0.82 9.3 0.0 2.6 2 1 1 3 3 3 0 Archaeal ATPase AAA_3 PF07726.6 CBZ08327.1 - 0.015 14.8 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CBZ08327.1 - 0.017 14.6 0.1 0.093 12.2 0.0 2.1 1 1 1 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.11 CBZ08327.1 - 0.018 14.2 0.1 0.043 13.0 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.1 CBZ08327.1 - 0.02 14.8 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 CBZ08327.1 - 0.021 13.9 2.4 0.15 11.1 0.0 2.6 2 1 1 3 3 3 0 KaiC NACHT PF05729.7 CBZ08327.1 - 0.023 14.3 0.1 0.24 11.0 0.0 2.1 1 1 1 2 2 2 0 NACHT domain Zeta_toxin PF06414.7 CBZ08327.1 - 0.027 13.5 0.0 0.056 12.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 CBZ08327.1 - 0.031 14.1 0.0 0.069 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 CBZ08327.1 - 0.092 12.3 0.0 0.24 11.0 0.0 1.7 2 0 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 CBZ08327.1 - 0.37 11.0 2.2 3.3 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Strabismus PF06638.6 CBZ08328.1 - 0.069 11.4 0.0 0.15 10.3 0.0 1.6 1 0 0 1 1 1 0 Strabismus protein WBP-1 PF11669.3 CBZ08328.1 - 2 8.5 0.0 2 8.5 0.0 3.9 4 0 0 4 4 4 0 WW domain-binding protein 1 Baculo_PP31 PF05311.6 CBZ08328.1 - 2.3 7.4 3.5 5.4 6.1 2.4 1.6 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) PBP1_TM PF14812.1 CBZ08329.1 - 5.3 7.4 9.3 15 5.9 0.5 3.1 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ADH_zinc_N PF00107.21 CBZ08330.1 - 1.4e-22 79.5 0.1 2.7e-22 78.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CBZ08330.1 - 2e-19 70.7 0.0 5e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CBZ08330.1 - 2.7e-11 43.1 0.2 7.3e-11 41.8 0.1 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 CBZ08330.1 - 0.065 13.2 0.9 0.14 12.1 0.6 1.6 1 0 0 1 1 1 0 NADH(P)-binding XRN_N PF03159.13 CBZ08331.1 - 0.15 11.4 1.6 0.2 11.0 1.1 1.2 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus Helicase_C_2 PF13307.1 CBZ08332.1 - 3.3e-41 141.0 0.0 6.1e-41 140.1 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 CBZ08332.1 - 3.6e-19 68.8 0.0 2e-06 27.3 0.0 4.3 4 0 0 4 4 4 4 DEAD_2 Cwf_Cwc_15 PF04889.7 CBZ08332.1 - 0.031 13.9 1.9 0.071 12.8 1.3 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Methyltransf_31 PF13847.1 CBZ08333.1 - 5.4e-09 35.8 0.0 7.5e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ08333.1 - 2.1e-07 31.5 0.0 5.4e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ08333.1 - 7.5e-05 23.0 0.0 0.00016 21.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBZ08333.1 - 0.00013 22.4 0.0 0.00036 20.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBZ08333.1 - 0.00034 20.0 0.0 0.00064 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 CBZ08333.1 - 0.0022 18.0 0.1 0.0049 16.8 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CBZ08333.1 - 0.003 16.7 0.0 0.0058 15.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.6 CBZ08333.1 - 0.0055 15.4 0.1 0.012 14.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.7 CBZ08333.1 - 0.0058 17.0 0.0 0.013 16.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 CBZ08333.1 - 0.0064 15.2 0.0 0.0096 14.6 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase RNA_Me_trans PF04252.8 CBZ08333.1 - 0.078 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Predicted SAM-dependent RNA methyltransferase FtsJ PF01728.14 CBZ08333.1 - 0.08 12.9 0.0 0.19 11.7 0.0 1.6 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 CBZ08333.1 - 0.08 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ArgK PF03308.11 CBZ08334.1 - 3e-72 242.6 0.0 4e-72 242.1 0.0 1.1 1 0 0 1 1 1 1 ArgK protein cobW PF02492.14 CBZ08334.1 - 1.2e-08 34.6 0.0 4.3e-08 32.7 0.0 1.9 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 CBZ08334.1 - 0.0013 18.1 0.0 0.0029 17.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.1 CBZ08334.1 - 0.0026 17.4 0.1 0.019 14.6 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain GTP_EFTU PF00009.22 CBZ08334.1 - 0.0028 17.1 0.0 0.14 11.5 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 CBZ08334.1 - 0.004 17.1 0.1 0.0085 16.0 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 CBZ08334.1 - 0.0059 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain CbiA PF01656.18 CBZ08334.1 - 0.0062 15.9 0.0 0.011 15.1 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain FtsK_SpoIIIE PF01580.13 CBZ08334.1 - 0.0079 15.6 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family MobB PF03205.9 CBZ08334.1 - 0.013 15.1 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 CBZ08334.1 - 0.068 12.7 1.0 6.2 6.3 0.1 2.5 1 1 1 2 2 2 0 AAA domain AAA_10 PF12846.2 CBZ08334.1 - 0.097 12.0 0.1 0.14 11.5 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain EmrE PF13536.1 CBZ08339.1 - 4e-05 23.7 9.7 4e-05 23.7 6.7 3.7 3 1 0 3 3 3 2 Multidrug resistance efflux transporter EIID-AGA PF03613.9 CBZ08339.1 - 0.0077 15.1 0.2 0.023 13.6 0.2 1.8 1 1 0 1 1 1 1 PTS system mannose/fructose/sorbose family IID component AAA_16 PF13191.1 CBZ08340.1 - 0.00094 19.2 0.2 0.0027 17.7 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 CBZ08340.1 - 0.0079 16.0 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 CBZ08340.1 - 0.017 14.1 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein AAA_25 PF13481.1 CBZ08340.1 - 0.039 13.3 0.2 0.077 12.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CBZ08340.1 - 0.24 11.0 0.0 0.39 10.3 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase Pkinase PF00069.20 CBZ08341.1 - 3.5e-17 62.4 0.0 4.9e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ08341.1 - 5.9e-09 35.3 0.0 8.3e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase zf-MYND PF01753.13 CBZ08342.1 - 0.028 14.2 9.6 0.056 13.3 6.7 1.5 1 0 0 1 1 1 0 MYND finger PolC_DP2 PF03833.8 CBZ08342.1 - 0.95 7.0 2.6 1.1 6.7 1.8 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-MYND PF01753.13 CBZ08344.1 - 0.0085 15.9 10.5 0.019 14.8 7.3 1.6 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 CBZ08344.1 - 3.4 7.0 6.4 8.5 5.7 4.4 1.6 1 0 0 1 1 1 0 Life-span regulatory factor N_Asn_amidohyd PF14736.1 CBZ08345.1 - 0.0055 15.6 0.0 0.49 9.2 0.0 2.7 2 0 0 2 2 2 2 Protein N-terminal asparagine amidohydrolase ABC_tran PF00005.22 CBZ08351.1 - 8.5e-10 39.0 0.0 1.2e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBZ08351.1 - 0.00017 21.6 0.0 0.00024 21.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 CBZ08351.1 - 0.017 14.3 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 CBZ08351.1 - 0.047 13.6 0.0 0.18 11.7 0.0 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Ribosomal_L23 PF00276.15 CBZ08354.1 - 1.1e-20 73.2 2.6 1.1e-20 73.2 1.8 2.3 2 1 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.8 CBZ08354.1 - 1.4e-11 44.1 13.3 1.4e-11 44.1 9.2 2.2 2 1 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Late_protein_L2 PF00513.13 CBZ08354.1 - 0.0015 17.4 1.0 0.0016 17.3 0.7 1.0 1 0 0 1 1 1 1 Late Protein L2 TusA PF01206.12 CBZ08354.1 - 0.017 14.7 0.1 0.036 13.6 0.1 1.6 1 0 0 1 1 1 0 Sulfurtransferase TusA P2 PF07194.6 CBZ08354.1 - 0.039 13.8 0.4 0.071 12.9 0.3 1.4 1 0 0 1 1 1 0 P2 response regulator binding domain LRR_8 PF13855.1 CBZ08355.1 - 2.7e-25 87.8 9.3 4.8e-06 26.2 0.2 4.7 4 0 0 4 4 4 4 Leucine rich repeat LRR_4 PF12799.2 CBZ08355.1 - 4.3e-24 83.6 9.8 1.4e-05 24.5 0.0 7.9 4 3 3 8 8 8 6 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 CBZ08355.1 - 3.5e-13 47.4 8.7 3.1 8.3 0.0 11.0 11 0 0 11 11 11 2 Leucine rich repeat LRR_1 PF00560.28 CBZ08355.1 - 5.3e-10 37.9 19.0 0.59 10.3 0.1 10.9 10 3 0 10 10 10 3 Leucine Rich Repeat LRR_6 PF13516.1 CBZ08355.1 - 5.9e-05 22.7 14.7 36 4.8 0.2 9.3 11 0 0 11 11 11 0 Leucine Rich repeat DUF1399 PF07173.7 CBZ08355.1 - 0.00025 21.3 3.6 0.048 13.9 0.1 3.6 3 1 1 4 4 4 1 Protein of unknown function (DUF1399) DUF3024 PF11225.3 CBZ08355.1 - 0.077 12.8 0.7 0.2 11.5 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3024) Pkinase PF00069.20 CBZ08357.1 - 3.5e-59 200.0 0.0 9.3e-38 129.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ08357.1 - 1.5e-32 112.7 0.0 1.3e-23 83.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CBZ08357.1 - 1.8e-05 24.6 0.0 0.11 12.1 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 CBZ08357.1 - 0.00042 19.3 0.1 0.00092 18.2 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CBZ08357.1 - 0.017 14.1 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 CBZ08357.1 - 0.056 12.2 0.0 0.086 11.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase BT1 PF03092.11 CBZ08358.1 - 1.6e-142 475.2 8.7 1.9e-142 475.0 6.0 1.0 1 0 0 1 1 1 1 BT1 family SIN1 PF05422.7 CBZ08361.1 - 0.011 14.3 0.0 0.029 12.8 0.0 1.6 2 0 0 2 2 2 0 Stress-activated map kinase interacting protein 1 (SIN1) E1-E2_ATPase PF00122.15 CBZ08362.1 - 1.2e-25 89.9 2.0 1.9e-25 89.2 1.4 1.2 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.21 CBZ08362.1 - 5.4e-15 54.6 0.0 8.8e-15 53.9 0.0 1.3 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus FWWh PF14922.1 CBZ08368.1 - 0.00069 19.1 2.7 0.0014 18.1 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function APG6 PF04111.7 CBZ08369.1 - 4.7e-16 58.7 0.0 1.2e-05 24.5 0.0 4.3 4 1 0 4 4 4 4 Autophagy protein Apg6 Amastin PF07344.6 CBZ08371.1 - 1.6e-54 183.7 7.6 1.8e-54 183.5 5.3 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ08371.1 - 8.4 6.0 14.9 3.2 7.4 8.0 2.0 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 CBZ08372.1 - 7.5e-54 181.5 8.0 8.8e-54 181.3 5.6 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Amastin PF07344.6 CBZ08373.1 - 2.2e-55 186.5 10.6 2.5e-55 186.3 7.4 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ08373.1 - 7e-05 22.5 9.2 7e-05 22.5 6.4 1.9 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF1467 PF07330.7 CBZ08373.1 - 0.036 13.8 3.9 1 9.1 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1467) Clc-like PF07062.7 CBZ08373.1 - 4 6.6 10.2 0.23 10.6 3.2 1.6 2 0 0 2 2 2 0 Clc-like Amastin PF07344.6 CBZ08374.1 - 2.2e-55 186.5 10.6 2.5e-55 186.3 7.4 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ08374.1 - 7e-05 22.5 9.2 7e-05 22.5 6.4 1.9 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF1467 PF07330.7 CBZ08374.1 - 0.036 13.8 3.9 1 9.1 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1467) Clc-like PF07062.7 CBZ08374.1 - 4 6.6 10.2 0.23 10.6 3.2 1.6 2 0 0 2 2 2 0 Clc-like Amastin PF07344.6 CBZ08375.1 - 7.4e-54 181.5 8.0 8.7e-54 181.3 5.6 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Peptidase_C1 PF00112.18 CBZ08377.1 - 5.9e-73 245.3 0.7 1.1e-72 244.5 0.5 1.4 1 0 0 1 1 1 1 Papain family cysteine protease DUF3586 PF12131.3 CBZ08377.1 - 2.2e-29 101.3 6.6 2.2e-29 101.3 4.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3586) Inhibitor_I29 PF08246.7 CBZ08377.1 - 5.7e-11 42.5 0.8 8.8e-11 41.9 0.5 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 CBZ08377.1 - 9e-07 27.7 0.1 0.0003 19.4 0.0 2.3 2 0 0 2 2 2 2 Peptidase C1-like family zf-RING_2 PF13639.1 CBZ08378.1 - 4.4e-09 36.0 5.5 4.4e-09 36.0 3.8 3.9 4 0 0 4 4 4 2 Ring finger domain zf-C3HC4_2 PF13923.1 CBZ08378.1 - 3.1e-06 27.1 6.4 3.1e-06 27.1 4.4 4.8 4 2 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBZ08378.1 - 2.1e-05 24.1 6.8 2.1e-05 24.1 4.7 4.8 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ08378.1 - 3.8e-05 23.3 4.3 3.8e-05 23.3 3.0 4.3 4 2 0 4 4 4 1 zinc-RING finger domain zf-HC5HC2H PF13771.1 CBZ08378.1 - 0.0028 17.7 2.5 0.0028 17.7 1.7 4.2 2 1 2 4 4 4 2 PHD-like zinc-binding domain zf-C3HC4_2 PF13923.1 CBZ08379.1 - 2.1e-10 40.4 8.9 4.6e-10 39.3 6.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBZ08379.1 - 1.4e-09 37.4 8.3 3e-09 36.4 5.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBZ08379.1 - 2e-08 33.9 8.1 5.1e-08 32.6 5.6 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 CBZ08379.1 - 2.5e-08 33.6 8.8 5.5e-08 32.5 6.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CBZ08379.1 - 5.8e-08 32.3 7.6 1.2e-07 31.2 5.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBZ08379.1 - 4e-07 29.5 7.5 8.2e-07 28.5 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBZ08379.1 - 6.6e-05 22.5 9.7 9.2e-05 22.0 5.5 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 CBZ08379.1 - 0.0029 17.6 4.9 0.0099 15.9 3.4 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-MIZ PF02891.15 CBZ08379.1 - 0.017 14.5 7.4 0.038 13.5 5.1 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger U-box PF04564.10 CBZ08379.1 - 0.035 14.0 0.1 0.11 12.4 0.1 1.9 1 0 0 1 1 1 0 U-box domain zf-Apc11 PF12861.2 CBZ08379.1 - 0.039 13.7 2.7 0.086 12.6 1.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 CBZ08379.1 - 0.47 10.0 6.7 0.93 9.0 4.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF4140 PF13600.1 CBZ08380.1 - 0.64 10.4 6.5 4.6 7.7 0.1 2.7 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) KduI PF04962.7 CBZ08381.1 - 0.0046 16.0 0.1 0.0051 15.9 0.1 1.1 1 0 0 1 1 1 1 KduI/IolB family GBA2_N PF12215.3 CBZ08381.1 - 0.014 14.5 0.2 0.016 14.4 0.2 1.0 1 0 0 1 1 1 0 beta-Glucocerebrosidase 2 N terminal Amidinotransf PF02274.12 CBZ08383.1 - 5.5e-24 84.7 0.0 7.1e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Amidinotransferase Pkinase PF00069.20 CBZ08384.1 - 1.9e-48 164.8 0.0 3e-48 164.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ08384.1 - 1.6e-33 115.8 0.0 3e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ08384.1 - 4.4e-06 25.8 0.0 7.9e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CBZ08384.1 - 0.0025 17.1 0.0 0.0063 15.8 0.0 1.7 1 0 0 1 1 1 1 RIO1 family Cmc1 PF08583.5 CBZ08385.1 - 0.056 13.2 1.8 0.11 12.3 1.0 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Hydrolase_2 PF07486.7 CBZ08385.1 - 0.12 12.8 0.0 0.15 12.6 0.0 1.1 1 0 0 1 1 1 0 Cell Wall Hydrolase CHCH PF06747.8 CBZ08385.1 - 0.34 10.8 4.0 6.6 6.7 0.2 2.6 3 0 0 3 3 3 0 CHCH domain NDUF_B7 PF05676.8 CBZ08385.1 - 2.6 7.5 6.3 8.7 5.8 0.9 2.5 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) DUF1981 PF09324.5 CBZ08386.1 - 0.39 10.2 0.1 2.6 7.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) Peptidase_M8 PF01457.11 CBZ08391.1 - 6.4e-262 869.4 0.8 7.3e-262 869.2 0.6 1.0 1 0 0 1 1 1 1 Leishmanolysin DUF1025 PF06262.6 CBZ08391.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase Histone PF00125.19 CBZ08394.1 - 2.9e-27 94.5 0.6 2.9e-27 94.5 0.4 1.8 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBZ08394.1 - 1.3e-05 25.2 0.0 2.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CBZ08394.1 - 2.1e-05 24.4 0.1 2.1e-05 24.4 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CBZ08394.1 - 0.0011 18.6 0.1 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 CBZ08394.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TMA7 PF09072.5 CBZ08394.1 - 0.15 12.5 3.0 0.24 11.8 2.1 1.4 1 0 0 1 1 1 0 Translation machinery associated TMA7 P34-Arc PF04045.9 CBZ08395.1 - 0.00016 21.0 0.0 0.00028 20.2 0.0 1.4 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Sulfate_tra_GLY PF13792.1 CBZ08403.1 - 0.051 13.2 0.0 0.079 12.6 0.0 1.2 1 0 0 1 1 1 0 Sulfate transporter N-terminal domain with GLY motif DUF2909 PF11137.3 CBZ08404.1 - 0.07 12.8 0.3 0.1 12.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) Glyco_transf_22 PF03901.12 CBZ08405.1 - 7.5e-54 183.3 23.9 1.6e-41 142.7 13.1 3.1 3 0 0 3 3 3 3 Alg9-like mannosyltransferase family UCH PF00443.24 CBZ08408.1 - 1.5e-24 86.5 0.0 2e-23 82.8 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBZ08408.1 - 0.21 10.9 0.0 3 7.2 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase AAA PF00004.24 CBZ08410.1 - 2.1e-45 154.1 0.1 1.1e-44 151.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBZ08410.1 - 7.6e-09 35.4 0.1 2.8e-08 33.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CBZ08410.1 - 6.1e-07 29.4 0.1 2.9e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CBZ08410.1 - 6.8e-07 29.4 0.8 3.3e-05 23.9 0.0 2.6 2 1 1 3 3 2 1 AAA ATPase domain AAA_22 PF13401.1 CBZ08410.1 - 7.7e-06 26.0 1.5 0.00019 21.6 0.2 2.7 2 1 0 2 2 1 1 AAA domain DUF815 PF05673.8 CBZ08410.1 - 7.1e-05 21.8 0.0 0.00013 20.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 CBZ08410.1 - 0.0002 21.3 0.0 0.00041 20.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBZ08410.1 - 0.00031 20.4 0.1 0.00073 19.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 CBZ08410.1 - 0.00054 19.6 1.8 0.035 13.7 0.0 3.6 3 1 1 4 4 4 1 NACHT domain AAA_17 PF13207.1 CBZ08410.1 - 0.00057 20.7 0.0 0.0014 19.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CBZ08410.1 - 0.00057 19.0 0.0 0.0013 17.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CBZ08410.1 - 0.00066 19.5 0.0 0.0018 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CBZ08410.1 - 0.00096 18.6 0.7 0.038 13.3 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.6 CBZ08410.1 - 0.0022 17.5 0.0 0.0081 15.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 CBZ08410.1 - 0.0025 17.5 0.1 0.0095 15.6 0.0 2.1 2 0 0 2 2 1 1 NTPase AAA_33 PF13671.1 CBZ08410.1 - 0.0041 17.0 0.0 0.009 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CBZ08410.1 - 0.0049 16.4 0.0 0.012 15.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CBZ08410.1 - 0.0054 15.8 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 CBZ08410.1 - 0.0063 15.6 0.1 0.018 14.2 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 CBZ08410.1 - 0.0069 15.5 2.5 0.86 8.6 0.0 2.9 3 0 0 3 3 3 1 KaiC Arch_ATPase PF01637.13 CBZ08410.1 - 0.0081 15.8 0.6 0.12 12.1 0.0 2.4 2 1 1 3 3 3 1 Archaeal ATPase AAA_24 PF13479.1 CBZ08410.1 - 0.0095 15.5 0.1 0.026 14.0 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBZ08410.1 - 0.0097 16.2 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 CBZ08410.1 - 0.013 14.2 0.0 0.032 12.9 0.0 1.5 1 1 0 1 1 1 0 TIP49 C-terminus IstB_IS21 PF01695.12 CBZ08410.1 - 0.014 14.7 0.0 0.03 13.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Bac_DnaA PF00308.13 CBZ08410.1 - 0.019 14.5 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein RNA_helicase PF00910.17 CBZ08410.1 - 0.021 14.9 0.0 0.052 13.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.21 CBZ08410.1 - 0.022 14.2 0.1 0.91 8.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_11 PF13086.1 CBZ08410.1 - 0.023 14.2 0.2 0.19 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF465 PF04325.8 CBZ08410.1 - 0.031 13.9 1.4 0.065 12.9 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF465) ABC_tran PF00005.22 CBZ08410.1 - 0.041 14.1 0.1 0.17 12.1 0.0 2.3 2 2 0 2 2 2 0 ABC transporter NB-ARC PF00931.17 CBZ08410.1 - 0.049 12.4 0.4 0.44 9.3 0.0 2.4 3 0 0 3 3 3 0 NB-ARC domain Robl_LC7 PF03259.12 CBZ08410.1 - 0.06 12.9 0.2 0.14 11.7 0.1 1.6 1 0 0 1 1 1 0 Roadblock/LC7 domain Histone PF00125.19 CBZ08410.1 - 0.061 13.4 0.0 0.24 11.5 0.0 2.0 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 cobW PF02492.14 CBZ08410.1 - 0.063 12.7 0.0 0.21 11.0 0.0 1.8 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Ins_P5_2-kin PF06090.7 CBZ08410.1 - 0.064 12.2 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase UPF0079 PF02367.12 CBZ08410.1 - 0.096 12.3 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Lactamase_B PF00753.22 CBZ08411.1 - 6e-12 45.6 1.8 8e-12 45.2 1.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CBZ08411.1 - 0.00042 19.9 0.1 0.00074 19.1 0.1 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain GST_N_2 PF13409.1 CBZ08411.1 - 0.11 12.4 0.0 9 6.3 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain RE_HindIII PF09518.5 CBZ08412.1 - 0.72 8.6 0.0 1.1 8.0 0.0 1.2 1 0 0 1 1 1 0 HindIII restriction endonuclease tRNA-synt_1e PF01406.14 CBZ08414.1 - 1.5e-113 378.9 0.0 2.1e-113 378.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 CBZ08414.1 - 9e-06 24.5 0.5 0.0022 16.6 0.0 3.3 3 0 0 3 3 3 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CBZ08414.1 - 0.00028 19.0 0.1 0.015 13.3 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1c PF00749.16 CBZ08414.1 - 0.0053 15.4 0.9 0.012 14.2 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain Orn_Arg_deC_N PF02784.11 CBZ08415.1 - 5e-80 268.3 0.0 7e-80 267.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 CBZ08415.1 - 4.7e-39 132.6 0.0 1.3e-38 131.3 0.0 1.8 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain KxDL PF10241.4 CBZ08416.1 - 0.0002 21.1 8.0 0.0002 21.1 5.5 5.6 6 1 0 6 6 6 1 Uncharacterized conserved protein DUF4279 PF14106.1 CBZ08416.1 - 0.81 9.5 5.0 1.7 8.5 0.2 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) SAC3_GANP PF03399.11 CBZ08417.1 - 3.3e-06 26.8 0.0 5.2e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family LrgB PF04172.11 CBZ08418.1 - 0.0048 16.0 0.0 0.0088 15.2 0.0 1.3 1 0 0 1 1 1 1 LrgB-like family NYD-SP28_assoc PF14775.1 CBZ08418.1 - 1.1 9.0 2.8 3.2 7.5 0.7 2.3 2 0 0 2 2 2 0 Sperm tail C-terminal domain YqjK PF13997.1 CBZ08418.1 - 4.3 7.5 10.3 15 5.8 0.4 3.2 2 1 0 2 2 2 0 YqjK-like protein Myotub-related PF06602.9 CBZ08419.1 - 4.9e-53 180.1 0.0 1.4e-21 76.7 0.0 3.9 4 0 0 4 4 4 3 Myotubularin-like phosphatase domain NOT2_3_5 PF04153.13 CBZ08422.1 - 6.1e-31 107.0 0.5 6.1e-31 107.0 0.4 3.4 3 1 0 3 3 3 1 NOT2 / NOT3 / NOT5 family DUF3499 PF12005.3 CBZ08422.1 - 2.7 8.1 17.4 0.16 12.1 0.2 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3499) GST_N_3 PF13417.1 CBZ08423.1 - 1.1e-10 41.6 0.0 2.6e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CBZ08423.1 - 4.4e-09 36.3 0.0 1.2e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CBZ08423.1 - 6e-08 32.5 0.0 1.2e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CBZ08423.1 - 0.017 15.5 0.1 0.22 12.0 0.0 2.5 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CBZ08423.1 - 0.074 13.0 0.1 0.3 11.1 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain PUF PF00806.14 CBZ08425.1 - 7.8e-35 116.4 7.8 6.6e-06 25.3 0.0 7.6 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat DUF4357 PF14267.1 CBZ08425.1 - 0.98 9.0 0.0 0.98 9.0 0.0 6.9 9 0 0 9 9 9 0 Domain of unknown function (DUF4357) DapB_N PF01113.15 CBZ08426.1 - 0.0051 16.7 0.1 0.016 15.0 0.1 1.9 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus S1-P1_nuclease PF02265.11 CBZ08427.1 - 5.2e-55 186.7 0.0 6.3e-55 186.5 0.0 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease DUF866 PF05907.8 CBZ08429.1 - 1.7e-27 95.8 0.0 2.1e-27 95.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Elf1 PF05129.8 CBZ08429.1 - 0.05 13.3 0.6 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Ribosomal_L37ae PF01780.14 CBZ08429.1 - 0.074 12.9 0.4 0.14 12.0 0.1 1.6 1 1 0 1 1 1 0 Ribosomal L37ae protein family DUF3222 PF11519.3 CBZ08429.1 - 0.14 12.1 0.7 0.55 10.2 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3222) DUF581 PF04570.9 CBZ08429.1 - 0.14 11.4 0.1 0.14 11.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF581) Fe-ADH PF00465.14 CBZ08430.1 - 9.6e-06 24.4 0.0 9.8e-06 24.4 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Bromodomain PF00439.20 CBZ08431.1 - 0.018 14.9 0.0 0.043 13.7 0.0 1.6 1 1 0 1 1 1 0 Bromodomain WW PF00397.21 CBZ08439.1 - 2.2e-07 30.5 0.1 4.8e-07 29.5 0.1 1.6 1 0 0 1 1 1 1 WW domain ATP-synt_F PF01990.12 CBZ08440.1 - 4e-35 120.0 0.0 4.9e-35 119.7 0.0 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit PGI PF00342.14 CBZ08441.1 - 1.4e-242 805.3 2.2 1.7e-242 805.1 1.5 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF4473 PF14747.1 CBZ08441.1 - 0.066 13.4 0.2 0.18 12.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) OsmC PF02566.14 CBZ08442.1 - 0.0072 16.4 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 OsmC-like protein YqaJ PF09588.5 CBZ08443.1 - 0.042 13.8 0.1 0.094 12.6 0.1 1.6 1 0 0 1 1 1 0 YqaJ-like viral recombinase domain TPR_11 PF13414.1 CBZ08444.1 - 1.1e-06 28.1 16.1 0.00079 19.0 2.3 5.7 6 1 0 6 6 6 2 TPR repeat TPR_19 PF14559.1 CBZ08444.1 - 0.00015 22.0 24.3 0.0026 18.0 0.7 7.1 6 1 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ08444.1 - 0.00031 20.2 9.0 0.028 14.0 0.6 5.8 7 0 0 7 7 7 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CBZ08444.1 - 0.0014 18.4 1.6 0.0084 15.9 0.4 2.8 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.12 CBZ08444.1 - 0.0026 17.5 2.0 0.0026 17.5 1.4 7.8 9 1 1 10 10 10 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ08444.1 - 0.0028 18.2 5.0 0.0028 18.2 3.5 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ08444.1 - 0.054 13.2 5.5 3.6 7.6 0.1 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ08444.1 - 6.5 6.7 29.5 0.13 12.1 3.0 7.6 10 1 0 10 10 10 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ08444.1 - 8 7.1 18.1 3.3 8.3 0.7 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat FUSC_2 PF13515.1 CBZ08445.1 - 2e-12 47.1 13.0 2.7e-12 46.7 6.3 2.5 2 0 0 2 2 2 1 Fusaric acid resistance protein-like Activator-TraM PF11657.3 CBZ08445.1 - 0.042 13.3 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 Transcriptional activator TraM DUF939 PF06081.6 CBZ08445.1 - 0.49 10.2 6.6 0.36 10.7 3.1 1.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF939) FUSC_2 PF13515.1 CBZ08446.1 - 1.3e-08 34.8 4.7 1.3e-08 34.8 3.3 2.6 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 CBZ08446.1 - 0.083 11.5 4.5 0.077 11.6 0.3 2.5 2 2 0 2 2 2 0 Aluminium activated malate transporter Sulfatase PF00884.18 CBZ08447.1 - 5.1e-05 22.6 0.1 0.00021 20.5 0.1 2.0 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 CBZ08447.1 - 0.00028 20.3 0.0 0.0082 15.5 0.0 2.7 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase TPR_11 PF13414.1 CBZ08448.1 - 9.8e-19 66.7 19.2 1.4e-11 43.8 0.4 5.1 3 1 3 6 6 6 5 TPR repeat TPR_1 PF00515.23 CBZ08448.1 - 8.4e-17 59.9 14.7 5.5e-05 22.5 0.0 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ08448.1 - 9e-17 59.5 25.4 0.0013 18.4 0.1 8.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ08448.1 - 1.2e-12 48.1 23.9 0.00026 21.5 0.8 6.1 3 1 3 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ08448.1 - 2.9e-12 46.7 6.8 4.2e-05 23.8 0.1 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ08448.1 - 3.2e-12 45.9 23.0 6.6e-05 23.2 0.2 7.4 7 2 2 9 9 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ08448.1 - 1.1e-11 43.6 4.1 0.0046 16.6 0.0 5.7 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ08448.1 - 2.5e-07 30.5 31.6 0.00038 20.3 1.1 6.5 3 1 3 7 7 7 4 Tetratricopeptide repeat TPR_15 PF13429.1 CBZ08448.1 - 3.2e-05 23.1 7.4 8.8e-05 21.6 5.2 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ08448.1 - 5.9e-05 22.5 16.8 0.1 12.4 0.2 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat APC8 PF04049.8 CBZ08448.1 - 0.00047 19.8 0.0 0.0021 17.8 0.0 2.0 1 1 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 Apc3 PF12895.2 CBZ08448.1 - 0.00084 19.4 17.7 0.017 15.2 0.8 5.7 5 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 CBZ08448.1 - 0.0015 18.6 8.7 0.1 12.8 0.2 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ08448.1 - 0.011 15.5 15.3 0.49 10.2 0.1 5.0 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 CBZ08448.1 - 0.02 14.7 11.2 0.16 11.9 1.1 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ08448.1 - 0.086 13.3 9.3 0.9 10.1 0.0 5.2 6 1 0 6 6 5 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.16 CBZ08450.1 - 2.2e-31 109.1 0.0 2.8e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II PriCT_2 PF08707.6 CBZ08451.1 - 5.9e-16 58.1 0.2 1.8e-15 56.5 0.1 1.8 1 0 0 1 1 1 1 Primase C terminal 2 (PriCT-2) BTV_NS2 PF04514.7 CBZ08452.1 - 1.3 7.8 14.5 1.9 7.3 10.1 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Metallophos PF00149.23 CBZ08453.1 - 1.6e-36 125.5 0.0 3.4e-36 124.5 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-TRAF PF02176.13 CBZ08453.1 - 0.00014 22.1 3.0 0.00014 22.1 2.1 3.1 1 1 2 3 3 3 1 TRAF-type zinc finger EF-hand_1 PF00036.27 CBZ08453.1 - 0.00061 18.9 0.0 0.055 12.7 0.0 3.0 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.1 CBZ08453.1 - 0.0037 17.3 0.1 0.35 11.0 0.0 3.7 3 1 1 4 4 4 2 EF-hand domain pair Metallophos_2 PF12850.2 CBZ08453.1 - 0.0045 16.8 0.0 0.0087 15.9 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain zinc_ribbon_2 PF13240.1 CBZ08453.1 - 0.0046 16.3 0.4 0.0046 16.3 0.3 2.7 2 1 0 2 2 2 1 zinc-ribbon domain EF-hand_8 PF13833.1 CBZ08453.1 - 0.0096 15.5 0.5 2 8.0 0.0 3.2 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 CBZ08453.1 - 0.018 14.8 0.3 1.4 9.0 0.0 3.6 4 0 0 4 4 4 0 EF-hand domain zf-ribbon_3 PF13248.1 CBZ08453.1 - 0.41 9.9 8.2 5.4 6.3 0.1 3.6 3 0 0 3 3 3 0 zinc-ribbon domain zf-tcix PF14952.1 CBZ08453.1 - 1.8 7.9 10.4 33 3.9 1.5 3.9 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding DUF1448 PF07289.6 CBZ08455.1 - 3.2e-148 493.1 0.0 3.7e-148 492.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1448) Vps36_ESCRT-II PF11605.3 CBZ08455.1 - 0.017 14.9 0.0 1.8 8.4 0.0 2.3 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 Voldacs PF03517.8 CBZ08455.1 - 0.031 14.1 0.1 4.1 7.2 0.0 2.6 3 0 0 3 3 3 0 Regulator of volume decrease after cellular swelling Viral_env_E26 PF11050.3 CBZ08456.1 - 0.014 14.5 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 Virus envelope protein E26 LRR_6 PF13516.1 CBZ08457.1 - 1.4e-22 77.1 9.4 0.013 15.4 0.1 11.6 11 1 1 12 12 12 6 Leucine Rich repeat LRR_4 PF12799.2 CBZ08457.1 - 2.4e-13 49.3 0.0 0.056 13.0 0.0 6.6 6 0 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBZ08457.1 - 1.4e-10 39.6 5.5 8.2 6.8 0.0 8.1 8 0 0 8 8 8 3 Leucine Rich Repeat LRR_7 PF13504.1 CBZ08457.1 - 0.00011 21.8 14.8 8.2 7.1 0.0 8.4 8 0 0 8 8 8 1 Leucine rich repeat LRR_8 PF13855.1 CBZ08457.1 - 0.0011 18.7 10.5 0.15 11.8 0.2 5.7 6 0 0 6 6 6 1 Leucine rich repeat Sipho_Gp157 PF05565.6 CBZ08457.1 - 6.1 6.4 15.4 8.1 5.9 8.7 2.4 1 1 1 2 2 2 0 Siphovirus Gp157 DUF962 PF06127.6 CBZ08458.1 - 9.3e-25 86.3 0.2 1.1e-24 86.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF962) Gly-zipper_YMGG PF13441.1 CBZ08458.1 - 0.11 11.9 4.9 0.16 11.5 3.4 1.2 1 0 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.1 CBZ08458.1 - 2.2 7.9 7.3 3.9 7.1 5.0 1.5 1 0 0 1 1 1 0 Glycine zipper UCR_Fe-S_N PF10399.4 CBZ08458.1 - 4.8 6.4 7.7 0.35 10.0 0.3 2.2 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF962 PF06127.6 CBZ08459.1 - 1.2e-23 82.7 0.0 1.4e-23 82.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF962) LRR_4 PF12799.2 CBZ08461.1 - 5.5e-08 32.2 0.0 0.0092 15.5 0.0 2.4 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ08461.1 - 4.2e-05 23.2 0.0 0.00084 19.0 0.0 2.1 1 1 1 2 2 2 2 Leucine rich repeat Lamp PF01299.12 CBZ08461.1 - 0.13 11.4 2.4 0.16 11.0 1.7 1.3 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) LRR_4 PF12799.2 CBZ08462.1 - 1.2e-18 66.2 8.5 0.095 12.3 0.9 7.6 4 2 3 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ08462.1 - 5.5e-13 48.4 11.6 0.0039 16.9 0.0 5.4 2 2 5 7 7 7 6 Leucine rich repeat LRR_1 PF00560.28 CBZ08462.1 - 1.1e-12 46.1 0.1 11 6.5 0.0 10.4 11 0 0 11 11 11 1 Leucine Rich Repeat LRR_6 PF13516.1 CBZ08462.1 - 0.0042 16.9 9.3 12 6.2 0.0 7.4 8 1 1 9 9 9 1 Leucine Rich repeat Rop-like PF05082.8 CBZ08462.1 - 0.075 12.5 0.9 25 4.4 0.0 5.2 8 0 0 8 8 8 0 Rop-like LRR_7 PF13504.1 CBZ08462.1 - 0.21 11.9 13.6 18 6.1 0.0 7.0 7 0 0 7 7 7 0 Leucine rich repeat LRR_4 PF12799.2 CBZ08464.1 - 3.2e-23 80.8 0.0 0.0017 17.9 0.0 6.5 2 1 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ08464.1 - 3.8e-15 55.3 1.3 0.0032 17.1 0.1 4.9 2 1 3 5 5 5 5 Leucine rich repeat LRR_1 PF00560.28 CBZ08464.1 - 2e-12 45.2 0.0 3.9 7.8 0.0 9.3 10 0 0 10 10 10 2 Leucine Rich Repeat LRR_6 PF13516.1 CBZ08464.1 - 0.007 16.3 7.3 15 6.0 0.0 6.6 8 0 0 8 8 8 1 Leucine Rich repeat Tme5_EGF_like PF09064.5 CBZ08464.1 - 0.83 9.3 7.0 2.4 7.8 4.9 1.8 1 0 0 1 1 1 0 Thrombomodulin like fifth domain, EGF-like LRR_4 PF12799.2 CBZ08465.1 - 4.5e-15 54.8 1.1 0.00098 18.6 0.3 4.4 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ08465.1 - 1.4e-10 40.7 1.5 0.00025 20.7 0.1 3.1 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 CBZ08465.1 - 1.6e-09 36.4 0.1 4.8 7.5 0.0 6.3 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.1 CBZ08465.1 - 0.05 13.6 2.3 82 3.7 0.0 4.8 6 0 0 6 6 6 0 Leucine Rich repeat LRR_8 PF13855.1 CBZ08467.1 - 9.8e-17 60.4 5.4 0.00011 21.8 0.0 5.0 3 1 3 6 6 6 6 Leucine rich repeat LRR_4 PF12799.2 CBZ08467.1 - 1.1e-16 59.9 5.2 0.011 15.3 0.0 7.2 1 1 7 9 9 9 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBZ08467.1 - 4.1e-10 38.2 0.0 5.6 7.3 0.0 8.8 11 0 0 11 11 11 3 Leucine Rich Repeat LRR_6 PF13516.1 CBZ08467.1 - 0.0043 16.9 1.9 22 5.5 0.0 4.9 6 0 0 6 6 6 2 Leucine Rich repeat Tme5_EGF_like PF09064.5 CBZ08467.1 - 1.6 8.3 7.0 3.4 7.3 4.9 1.5 1 0 0 1 1 1 0 Thrombomodulin like fifth domain, EGF-like LRR_4 PF12799.2 CBZ08469.1 - 5.4e-27 92.9 13.8 0.0031 17.0 0.0 8.7 5 2 4 10 10 10 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ08469.1 - 4e-19 68.1 18.0 0.00089 18.9 0.1 7.4 1 1 8 11 11 11 10 Leucine rich repeat LRR_1 PF00560.28 CBZ08469.1 - 9.3e-14 49.3 4.1 4.2 7.7 0.0 10.9 11 0 0 11 11 11 3 Leucine Rich Repeat LRR_6 PF13516.1 CBZ08469.1 - 0.8 9.9 18.4 27 5.2 0.2 8.9 13 0 0 13 13 13 0 Leucine Rich repeat LRR_4 PF12799.2 CBZ08470.1 - 9.6e-16 57.0 0.0 0.00086 18.8 0.0 4.5 2 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ08470.1 - 2.2e-10 40.0 0.4 0.00014 21.5 0.0 3.2 1 1 2 3 3 3 3 Leucine rich repeat DnaJ PF00226.26 CBZ08472.1 - 1.6e-13 50.1 0.1 5.7e-13 48.3 0.0 1.9 2 0 0 2 2 2 1 DnaJ domain zf-C3HC4_3 PF13920.1 CBZ08472.1 - 0.15 11.7 15.1 0.041 13.5 7.8 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PDZ_2 PF13180.1 CBZ08473.1 - 0.01 15.7 0.0 0.034 14.0 0.0 1.8 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.19 CBZ08473.1 - 0.042 14.0 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) KIF1B PF12423.3 CBZ08473.1 - 0.046 13.7 0.0 0.24 11.4 0.0 2.3 2 0 0 2 2 2 0 Kinesin protein 1B SlyX PF04102.7 CBZ08474.1 - 0.017 15.4 0.8 0.055 13.8 0.6 1.9 1 0 0 1 1 1 0 SlyX Fez1 PF06818.10 CBZ08474.1 - 0.11 12.4 0.2 0.25 11.3 0.2 1.6 1 0 0 1 1 1 0 Fez1 DUF4201 PF13870.1 CBZ08474.1 - 0.17 11.2 0.3 0.26 10.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF3639 PF12341.3 CBZ08475.1 - 1.9e-09 37.3 0.5 6e-09 35.7 0.3 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3639) WD40 PF00400.27 CBZ08475.1 - 1.3e-05 24.8 2.2 0.29 11.0 0.0 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF2121 PF09894.4 CBZ08475.1 - 0.086 12.1 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2121) Zip PF02535.17 CBZ08476.1 - 6.3 5.7 7.0 11 4.8 4.1 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter Oxidored_FMN PF00724.15 CBZ08477.1 - 9.7e-83 277.9 0.0 3e-82 276.3 0.0 1.6 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 CBZ08477.1 - 0.13 11.1 0.0 0.22 10.2 0.0 1.4 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Oxidored_FMN PF00724.15 CBZ08478.1 - 6.6e-140 465.9 0.0 2.1e-77 260.4 0.0 2.1 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 CBZ08478.1 - 0.0035 16.2 0.7 0.22 10.2 0.0 3.0 3 0 0 3 3 3 1 Dihydrouridine synthase (Dus) MULE PF10551.4 CBZ08478.1 - 0.1 12.7 0.1 0.68 10.1 0.0 2.3 2 0 0 2 2 2 0 MULE transposase domain DAGK_prokar PF01219.14 CBZ08479.1 - 0.19 11.3 0.0 0.54 9.8 0.0 1.7 2 0 0 2 2 2 0 Prokaryotic diacylglycerol kinase DUF2404 PF10296.4 CBZ08480.1 - 8.8e-20 70.6 0.0 1.6e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) DUF2404 PF10296.4 CBZ08481.1 - 1.6e-22 79.4 0.0 3.2e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) CSD PF00313.17 CBZ08482.1 - 0.00046 19.9 0.0 0.021 14.6 0.0 2.5 2 0 0 2 2 2 1 'Cold-shock' DNA-binding domain FTR PF01913.13 CBZ08482.1 - 3.6 7.2 5.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase ABC_tran PF00005.22 CBZ08483.1 - 5.3e-11 42.9 0.0 0.00012 22.3 0.1 2.7 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CBZ08483.1 - 7.6e-05 22.8 0.0 0.12 12.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 CBZ08483.1 - 0.0019 17.6 0.0 0.0035 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain AAA_16 PF13191.1 CBZ08483.1 - 0.0064 16.4 0.9 0.021 14.8 0.6 1.8 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 CBZ08483.1 - 0.013 14.7 0.1 0.025 13.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 CBZ08483.1 - 0.016 14.6 0.0 0.045 13.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain TMEM51 PF15345.1 CBZ08483.1 - 0.041 13.5 0.1 0.11 12.1 0.1 1.7 1 0 0 1 1 1 0 Transmembrane protein 51 AAA_22 PF13401.1 CBZ08483.1 - 0.11 12.5 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 CBZ08483.1 - 0.22 11.2 0.0 0.45 10.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Guanylate_kin PF00625.16 CBZ08483.1 - 0.33 10.3 0.1 0.74 9.2 0.0 1.6 2 0 0 2 2 2 0 Guanylate kinase AAA_23 PF13476.1 CBZ08483.1 - 0.88 9.8 0.1 1.5 9.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 CBZ08483.1 - 1.6 7.6 0.0 6.7 5.6 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain ABC_ATPase PF09818.4 CBZ08483.1 - 2.8 6.4 2.9 1.9 6.9 0.0 2.1 3 0 0 3 3 3 0 Predicted ATPase of the ABC class SNARE_assoc PF09335.6 CBZ08485.1 - 1.6e-20 73.5 5.5 3.8e-20 72.3 3.8 1.7 1 0 0 1 1 1 1 SNARE associated Golgi protein DUF4117 PF13491.1 CBZ08485.1 - 3 7.2 8.7 7.2 6.0 3.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4117) zf-C3HC4_2 PF13923.1 CBZ08486.1 - 3.3e-06 27.0 12.6 1.8e-05 24.6 6.9 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBZ08486.1 - 0.00023 20.7 8.6 0.00023 20.7 6.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBZ08486.1 - 0.0015 18.2 6.4 0.0032 17.1 4.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 CBZ08486.1 - 0.059 13.2 17.9 0.033 14.0 9.7 2.4 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.1 CBZ08486.1 - 2 8.2 19.1 0.07 12.8 8.1 2.4 3 0 0 3 3 3 0 zinc-RING finger domain Cellulase-like PF12876.2 CBZ08486.1 - 2.5 8.6 6.3 1.2 9.6 0.5 3.4 3 1 1 4 4 4 0 Sugar-binding cellulase-like Peptidase_M1 PF01433.15 CBZ08487.1 - 7.8e-71 239.2 0.0 6.4e-51 173.6 0.0 3.0 2 1 0 2 2 2 2 Peptidase family M1 Peptidase_MA_2 PF13485.1 CBZ08487.1 - 5.5e-11 42.5 0.0 1.2e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily ERAP1_C PF11838.3 CBZ08487.1 - 0.0063 15.7 0.0 0.014 14.6 0.0 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain FA_desaturase PF00487.19 CBZ08488.1 - 0.022 14.1 1.1 0.032 13.6 0.1 1.6 2 0 0 2 2 2 0 Fatty acid desaturase Methyltransf_31 PF13847.1 CBZ08489.1 - 3e-14 52.8 0.0 4.1e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CBZ08489.1 - 4.9e-12 45.5 0.0 7.8e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 CBZ08489.1 - 6.2e-12 46.1 0.1 1.1e-11 45.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBZ08489.1 - 1.3e-09 38.1 0.0 2.8e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 CBZ08489.1 - 5e-09 35.5 0.0 6.1e-09 35.3 0.0 1.0 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_11 PF08241.7 CBZ08489.1 - 1.5e-08 35.0 0.0 3.6e-08 33.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBZ08489.1 - 3.1e-08 33.5 0.1 7.9e-08 32.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CBZ08489.1 - 3.9e-08 32.8 0.7 5.8e-08 32.2 0.1 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.1 CBZ08489.1 - 4e-07 30.3 0.0 1e-06 29.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ08489.1 - 2.6e-06 27.8 0.0 5.4e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 CBZ08489.1 - 3.6e-06 25.8 0.1 5.2e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) TehB PF03848.9 CBZ08489.1 - 4e-05 22.8 0.5 9.3e-05 21.6 0.4 1.6 1 1 0 1 1 1 1 Tellurite resistance protein TehB CMAS PF02353.15 CBZ08489.1 - 0.00027 20.1 0.1 0.00042 19.4 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 CBZ08489.1 - 0.0012 18.8 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.1 CBZ08489.1 - 0.0028 17.3 0.0 0.0047 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 CBZ08489.1 - 0.004 16.7 0.0 0.0064 16.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_4 PF02390.12 CBZ08489.1 - 0.01 14.9 0.0 0.018 14.0 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase PCMT PF01135.14 CBZ08489.1 - 0.011 15.2 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.6 CBZ08489.1 - 0.023 14.1 0.1 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) SET PF00856.23 CBZ08492.1 - 1.7e-08 34.9 1.6 3.4e-08 33.9 0.2 2.0 2 0 0 2 2 2 1 SET domain zf-MYND PF01753.13 CBZ08492.1 - 4e-05 23.3 6.7 4e-05 23.3 4.6 2.8 3 0 0 3 3 3 1 MYND finger TPR_2 PF07719.12 CBZ08492.1 - 0.0064 16.3 0.4 0.24 11.3 0.6 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ08492.1 - 0.037 13.6 2.0 0.14 11.7 0.8 2.5 1 1 1 2 2 2 0 TPR repeat TPR_12 PF13424.1 CBZ08492.1 - 0.18 11.7 1.4 0.63 10.0 0.4 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ08492.1 - 0.33 10.6 2.1 4.5 7.0 0.7 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat RNase_H2_suC PF08615.6 CBZ08493.1 - 1.7e-06 27.9 0.0 1.5e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) FAM91_C PF14648.1 CBZ08494.1 - 2.9e-160 534.0 0.0 3.6e-160 533.7 0.0 1.1 1 0 0 1 1 1 1 FAM91 C-terminus FAM91_N PF14647.1 CBZ08494.1 - 1e-118 395.9 0.7 1.4e-118 395.4 0.5 1.2 1 0 0 1 1 1 1 FAM91 N-terminus Vps39_2 PF10367.4 CBZ08495.1 - 1.7e-26 92.5 0.1 3.7e-26 91.4 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 CBZ08495.1 - 7e-10 38.8 0.1 7.2e-09 35.6 0.1 2.6 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.15 CBZ08495.1 - 3.8e-05 23.3 0.1 0.00053 19.6 0.0 2.3 2 0 0 2 2 2 1 Region in Clathrin and VPS Rad50_zn_hook PF04423.9 CBZ08495.1 - 0.12 11.8 0.1 0.33 10.4 0.1 1.7 1 0 0 1 1 1 0 Rad50 zinc hook motif Abhydrolase_5 PF12695.2 CBZ08496.1 - 4.9e-11 42.5 0.0 9.3e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBZ08496.1 - 3.6e-05 23.7 0.1 0.00077 19.4 0.1 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CBZ08496.1 - 0.087 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DLH PF01738.13 CBZ08496.1 - 0.1 11.8 0.1 0.66 9.2 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Tubulin PF00091.20 CBZ08498.1 - 2.1e-67 227.0 0.0 2.9e-67 226.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBZ08498.1 - 4.6e-50 168.8 0.0 7.5e-50 168.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CBZ08498.1 - 0.007 15.8 0.0 0.016 14.7 0.0 1.6 2 0 0 2 2 2 1 Tubulin domain Dynein_heavy PF03028.10 CBZ08501.1 - 1.8e-233 776.6 0.0 8.3e-174 579.4 0.0 2.4 2 0 0 2 2 2 2 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 CBZ08501.1 - 1.1e-114 381.7 0.1 3.7e-114 380.0 0.1 2.0 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 DHC_N2 PF08393.8 CBZ08501.1 - 9.4e-108 360.3 0.2 9.4e-108 360.3 0.2 2.8 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.7 CBZ08501.1 - 7.4e-107 358.1 0.5 5.6e-106 355.2 0.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 AAA_8 PF12780.2 CBZ08501.1 - 3.1e-93 311.6 0.1 7.3e-93 310.3 0.1 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.2 CBZ08501.1 - 3.2e-87 292.0 0.8 8.7e-87 290.6 0.5 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 MT PF12777.2 CBZ08501.1 - 2.4e-86 289.6 11.0 5.9e-86 288.3 7.6 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 CBZ08501.1 - 1.3e-84 282.5 0.2 3.1e-84 281.3 0.1 1.7 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_5 PF07728.9 CBZ08501.1 - 9.2e-23 80.5 0.0 1.3e-07 31.3 0.0 5.5 5 0 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CBZ08501.1 - 2.8e-08 33.9 1.1 0.12 12.3 0.0 5.6 5 0 0 5 5 4 2 AAA ATPase domain AAA PF00004.24 CBZ08501.1 - 7.2e-07 29.4 0.0 0.095 12.9 0.0 3.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBZ08501.1 - 1.8e-05 24.9 0.6 5.2 7.2 0.0 5.7 5 0 0 5 5 4 1 AAA domain AAA_18 PF13238.1 CBZ08501.1 - 0.00016 21.9 0.1 6.4 7.0 0.0 5.7 4 0 0 4 4 4 1 AAA domain AAA_19 PF13245.1 CBZ08501.1 - 0.00069 19.3 2.3 12 5.7 0.4 4.0 4 0 0 4 4 3 0 Part of AAA domain Mg_chelatase PF01078.16 CBZ08501.1 - 0.0057 15.8 0.4 0.59 9.2 0.0 3.7 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 CBZ08501.1 - 0.006 17.3 1.8 0.68 10.7 0.0 5.3 5 0 0 5 5 4 1 AAA domain UPF0079 PF02367.12 CBZ08501.1 - 0.012 15.2 0.4 25 4.4 0.0 3.8 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 Reo_sigmaC PF04582.7 CBZ08501.1 - 0.16 11.1 11.2 0.091 11.9 0.1 3.9 4 0 0 4 4 4 0 Reovirus sigma C capsid protein Cpn60_TCP1 PF00118.19 CBZ08502.1 - 5.9e-146 486.9 3.6 6.7e-146 486.7 2.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Blt1 PF12754.2 CBZ08502.1 - 0.2 11.1 0.0 0.38 10.3 0.0 1.4 1 0 0 1 1 1 0 Cell-cycle control medial ring component Ribosomal_L44 PF00935.14 CBZ08503.1 - 2.9e-31 107.3 8.9 4.4e-31 106.7 6.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 RPA_interact_C PF14768.1 CBZ08503.1 - 0.11 12.8 0.4 0.61 10.5 0.3 1.9 1 1 0 1 1 1 0 Replication protein A interacting C-terminal P5CR_dimer PF14748.1 CBZ08504.1 - 2.4e-37 127.2 1.2 4e-37 126.4 0.8 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 CBZ08504.1 - 5.9e-16 58.6 0.0 1.2e-15 57.6 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 CBZ08504.1 - 2.1e-06 27.7 0.0 3.6e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 CBZ08504.1 - 1.2e-05 24.7 0.0 2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 CBZ08504.1 - 0.001 19.2 0.0 0.0031 17.6 0.0 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 CBZ08504.1 - 0.0015 18.2 1.3 0.014 15.0 0.9 2.1 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 CBZ08504.1 - 0.0076 15.4 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PDH PF02153.12 CBZ08504.1 - 0.1 11.4 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase MFS_1 PF07690.11 CBZ08505.1 - 7.3e-17 61.1 30.2 2.4e-13 49.5 17.9 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 CBZ08505.1 - 4.8e-10 39.1 15.3 4.8e-10 39.1 10.6 2.6 2 2 0 2 2 2 1 Nodulin-like LRR_4 PF12799.2 CBZ08506.1 - 6.2e-11 41.6 0.0 0.52 9.9 0.0 5.8 5 1 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ08506.1 - 0.0073 16.0 1.7 12 5.7 0.1 4.9 2 2 4 6 6 6 1 Leucine rich repeat LRR_1 PF00560.28 CBZ08506.1 - 0.046 13.7 0.6 54 4.4 0.1 5.0 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_7 PF13504.1 CBZ08506.1 - 0.048 13.8 2.0 44 4.9 0.1 5.2 4 1 1 5 5 5 0 Leucine rich repeat MDMPI_C PF07398.6 CBZ08506.1 - 0.14 12.7 2.1 0.37 11.3 1.4 1.8 1 0 0 1 1 1 0 MDMPI C-terminal domain Tubulin PF00091.20 CBZ08507.1 - 2.6e-67 226.8 0.0 3.6e-67 226.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBZ08507.1 - 5.3e-50 168.6 0.0 8.8e-50 167.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CBZ08507.1 - 0.0081 15.6 0.0 0.018 14.5 0.0 1.6 2 0 0 2 2 2 1 Tubulin domain ELO PF01151.13 CBZ08513.1 - 6.3e-80 268.0 24.9 7.3e-80 267.8 17.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.13 CBZ08514.1 - 6.3e-80 268.0 24.9 7.3e-80 267.8 17.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.13 CBZ08515.1 - 4.9e-78 261.8 23.0 5.7e-78 261.6 15.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family UPF0233 PF06781.7 CBZ08515.1 - 0.28 10.8 2.0 1 9.0 0.2 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) Claudin_3 PF06653.6 CBZ08515.1 - 1.1 8.9 12.4 0.43 10.2 6.1 2.0 2 0 0 2 2 2 0 Tight junction protein, Claudin-like DNA_pol_A PF00476.15 CBZ08517.1 - 4.8e-27 94.5 0.0 8.4e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A XK-related PF09815.4 CBZ08518.1 - 0.01 14.8 1.5 0.012 14.6 1.0 1.2 1 0 0 1 1 1 0 XK-related protein Chorion_2 PF03964.10 CBZ08519.1 - 0.26 11.8 0.2 0.26 11.8 0.2 3.4 3 1 0 3 3 3 0 Chorion family 2 DUF3186 PF11382.3 CBZ08525.1 - 0.00054 19.1 10.2 0.12 11.5 0.4 4.0 4 0 0 4 4 4 2 Protein of unknown function (DUF3186) KxDL PF10241.4 CBZ08525.1 - 0.0071 16.2 0.1 7.9 6.4 0.0 3.0 2 0 0 2 2 2 2 Uncharacterized conserved protein cNMP_binding PF00027.24 CBZ08528.1 - 1.7e-09 37.3 0.0 3.8e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Pkinase PF00069.20 CBZ08529.1 - 1.3e-55 188.3 0.0 2.5e-55 187.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ08529.1 - 1.5e-40 138.9 0.0 2.6e-40 138.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.24 CBZ08529.1 - 8.1e-28 96.0 0.3 2.2e-14 53.0 0.1 2.8 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain PAS_9 PF13426.1 CBZ08529.1 - 7.9e-08 32.6 0.0 6.7e-07 29.6 0.0 2.7 4 0 0 4 4 4 1 PAS domain Kinase-like PF14531.1 CBZ08529.1 - 3.5e-07 29.4 0.0 2.2e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like PAS PF00989.19 CBZ08529.1 - 4.1e-07 29.7 0.0 1.3e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 PAS fold RIO1 PF01163.17 CBZ08529.1 - 0.063 12.6 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Ribosomal_60s PF00428.14 CBZ08530.1 - 1.1e-22 80.2 12.8 1.4e-22 79.8 8.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_60s PF00428.14 CBZ08531.1 - 1.1e-22 80.2 12.8 1.4e-22 79.8 8.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Exo_endo_phos PF03372.18 CBZ08532.1 - 1.5e-20 74.1 0.0 4.2e-20 72.7 0.0 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.22 CBZ08532.1 - 3e-11 43.1 0.0 5.7e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain DnaJ PF00226.26 CBZ08533.1 - 3.1e-26 90.8 2.1 5.2e-26 90.1 1.4 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 CBZ08533.1 - 1e-09 38.2 13.9 1.9e-09 37.4 9.7 1.4 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 CBZ08533.1 - 1.2e-05 25.1 0.0 0.014 15.3 0.0 3.4 2 1 0 2 2 2 2 DnaJ C terminal domain Nucleoside_tran PF01733.13 CBZ08534.1 - 3.8e-34 118.2 2.9 3.8e-34 118.2 2.0 2.4 2 1 0 2 2 2 1 Nucleoside transporter Nucleoside_tran PF01733.13 CBZ08535.1 - 3.8e-34 118.2 2.9 3.8e-34 118.2 2.0 2.2 2 1 0 2 2 2 1 Nucleoside transporter Nucleoside_tran PF01733.13 CBZ08536.1 - 3.8e-34 118.2 2.9 3.8e-34 118.2 2.0 2.4 2 1 0 2 2 2 1 Nucleoside transporter IQ PF00612.22 CBZ08538.1 - 0.19 11.4 23.1 0.51 10.1 1.8 3.9 3 0 0 3 3 3 0 IQ calmodulin-binding motif MutS_V PF00488.16 CBZ08539.1 - 3.5e-57 193.4 0.0 1.1e-56 191.8 0.0 1.7 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CBZ08539.1 - 4.7e-30 104.8 0.2 7.8e-30 104.1 0.2 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 CBZ08539.1 - 9.7e-19 67.4 0.0 1.6e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.13 CBZ08539.1 - 0.00069 19.7 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 MutS family domain IV DHO_dh PF01180.16 CBZ08541.1 - 3.2e-67 226.5 0.0 3.6e-67 226.3 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase F_bP_aldolase PF01116.15 CBZ08541.1 - 0.03 13.4 0.0 0.044 12.8 0.0 1.2 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-II PcrB PF01884.12 CBZ08541.1 - 0.035 13.3 0.0 0.054 12.7 0.0 1.3 1 0 0 1 1 1 0 PcrB family FMN_dh PF01070.13 CBZ08541.1 - 0.063 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase DUF1738 PF08401.6 CBZ08542.1 - 8.9e-05 22.2 0.0 0.032 13.9 0.0 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF1738) Exo_endo_phos PF03372.18 CBZ08543.1 - 9.7e-24 84.6 0.1 1.2e-23 84.2 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MGC-24 PF05283.6 CBZ08543.1 - 6.7 6.4 10.1 12 5.6 7.0 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) MSP1_C PF07462.6 CBZ08543.1 - 10 4.4 5.5 17 3.6 3.8 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF3184 PF11380.3 CBZ08547.1 - 1.2e-61 208.6 4.3 1.6e-61 208.1 3.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3184) DUF3184 PF11380.3 CBZ08548.1 - 1.5e-218 727.1 20.7 3.9e-172 573.7 2.5 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3184) DUF3184 PF11380.3 CBZ08550.1 - 0 1032.9 24.7 1.2e-213 711.0 11.4 3.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3184) Tbf5 PF06331.7 CBZ08551.1 - 0.079 12.7 0.0 15 5.4 0.0 2.1 2 0 0 2 2 2 0 Transcription factor TFIIH complex subunit Tfb5 Crl PF07417.7 CBZ08552.1 - 0.9 9.2 0.0 2.1 8.0 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator Crl TRAPP PF04051.11 CBZ08553.1 - 5.4e-28 97.4 0.0 6.9e-28 97.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component C_GCAxxG_C_C PF09719.5 CBZ08553.1 - 0.11 12.2 0.1 0.64 9.8 0.0 2.1 1 1 1 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) GTP_EFTU PF00009.22 CBZ08554.1 - 8.8e-54 181.7 0.0 1.5e-53 181.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBZ08554.1 - 5.7e-36 122.6 0.1 3.6e-35 120.0 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CBZ08554.1 - 6.3e-18 64.6 0.4 6.3e-18 64.6 0.3 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CBZ08554.1 - 1.8e-05 24.3 0.2 5.4e-05 22.7 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 CBZ08554.1 - 4.1e-05 23.5 0.0 0.00014 21.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CBZ08554.1 - 0.0035 16.5 0.1 0.018 14.2 0.0 2.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 CBZ08554.1 - 0.0068 16.8 0.3 0.07 13.6 0.2 2.3 1 1 0 1 1 1 1 Miro-like protein Semialdhyde_dhC PF02774.13 CBZ08554.1 - 0.019 14.8 0.1 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain GTP_EFTU PF00009.22 CBZ08555.1 - 1.2e-53 181.4 0.0 2e-53 180.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBZ08555.1 - 7.8e-36 122.2 0.1 4.4e-35 119.8 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CBZ08555.1 - 7.5e-18 64.4 0.4 7.5e-18 64.4 0.3 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CBZ08555.1 - 2.1e-05 24.0 0.1 6.7e-05 22.4 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 CBZ08555.1 - 5.1e-05 23.2 0.0 0.00017 21.5 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CBZ08555.1 - 0.005 16.0 0.1 0.028 13.6 0.0 2.2 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit Miro PF08477.8 CBZ08555.1 - 0.0091 16.4 0.3 0.083 13.3 0.2 2.2 1 1 0 1 1 1 1 Miro-like protein Semialdhyde_dhC PF02774.13 CBZ08555.1 - 0.025 14.4 0.1 0.25 11.1 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain GTP_EFTU PF00009.22 CBZ08556.1 - 8.8e-54 181.7 0.0 1.5e-53 181.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBZ08556.1 - 5.7e-36 122.6 0.1 3.6e-35 120.0 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CBZ08556.1 - 6.3e-18 64.6 0.4 6.3e-18 64.6 0.3 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CBZ08556.1 - 1.8e-05 24.3 0.2 5.4e-05 22.7 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 CBZ08556.1 - 4.1e-05 23.5 0.0 0.00014 21.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CBZ08556.1 - 0.0035 16.5 0.1 0.018 14.2 0.0 2.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 CBZ08556.1 - 0.0068 16.8 0.3 0.07 13.6 0.2 2.3 1 1 0 1 1 1 1 Miro-like protein Semialdhyde_dhC PF02774.13 CBZ08556.1 - 0.019 14.8 0.1 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain GTP_EFTU PF00009.22 CBZ08557.1 - 1.8e-46 157.9 0.7 3.3e-46 157.1 0.5 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBZ08557.1 - 5.6e-36 122.6 0.1 3.6e-35 120.0 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CBZ08557.1 - 6.3e-18 64.6 0.4 6.3e-18 64.6 0.3 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CBZ08557.1 - 1.4e-05 24.6 0.4 4.2e-05 23.0 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 CBZ08557.1 - 4.2e-05 23.4 0.0 0.00014 21.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CBZ08557.1 - 0.0071 16.8 0.3 0.07 13.6 0.2 2.2 1 1 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 CBZ08557.1 - 0.013 14.7 0.1 0.043 13.0 0.1 2.0 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit Semialdhyde_dhC PF02774.13 CBZ08557.1 - 0.026 14.3 0.2 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain GTP_EFTU PF00009.22 CBZ08558.1 - 8.8e-54 181.7 0.0 1.5e-53 181.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBZ08558.1 - 5.7e-36 122.6 0.1 3.6e-35 120.0 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CBZ08558.1 - 6.3e-18 64.6 0.4 6.3e-18 64.6 0.3 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CBZ08558.1 - 1.8e-05 24.3 0.2 5.4e-05 22.7 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 CBZ08558.1 - 4.1e-05 23.5 0.0 0.00014 21.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CBZ08558.1 - 0.0035 16.5 0.1 0.018 14.2 0.0 2.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 CBZ08558.1 - 0.0068 16.8 0.3 0.07 13.6 0.2 2.3 1 1 0 1 1 1 1 Miro-like protein Semialdhyde_dhC PF02774.13 CBZ08558.1 - 0.019 14.8 0.1 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain GTP_EFTU PF00009.22 CBZ08559.1 - 8.8e-54 181.7 0.0 1.5e-53 181.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBZ08559.1 - 5.7e-36 122.6 0.1 3.6e-35 120.0 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CBZ08559.1 - 6.3e-18 64.6 0.4 6.3e-18 64.6 0.3 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CBZ08559.1 - 1.8e-05 24.3 0.2 5.4e-05 22.7 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 CBZ08559.1 - 4.1e-05 23.5 0.0 0.00014 21.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CBZ08559.1 - 0.0035 16.5 0.1 0.018 14.2 0.0 2.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 CBZ08559.1 - 0.0068 16.8 0.3 0.07 13.6 0.2 2.3 1 1 0 1 1 1 1 Miro-like protein Semialdhyde_dhC PF02774.13 CBZ08559.1 - 0.019 14.8 0.1 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain DEAD PF00270.24 CBZ08560.1 - 9.5e-16 57.7 0.4 1.4e-15 57.2 0.3 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CBZ08560.1 - 5.9e-06 26.2 0.0 9.2e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SE PF00437.15 CBZ08560.1 - 0.021 13.7 0.0 0.024 13.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein UvrD-helicase PF00580.16 CBZ08560.1 - 0.053 12.8 0.0 0.092 12.0 0.0 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain PhoH PF02562.11 CBZ08560.1 - 0.075 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein DUF4379 PF14311.1 CBZ08562.1 - 4.5e-19 67.9 10.2 8.1e-12 44.7 0.4 3.2 2 1 1 3 3 3 2 Domain of unknown function (DUF4379) Elf1 PF05129.8 CBZ08562.1 - 0.0076 15.9 1.6 2.6 7.7 0.1 3.1 3 0 0 3 3 3 1 Transcription elongation factor Elf1 like SprT-like PF10263.4 CBZ08562.1 - 0.019 14.6 4.0 2 8.0 0.1 2.4 2 1 0 2 2 2 0 SprT-like family Zn_Tnp_IS1595 PF12760.2 CBZ08562.1 - 0.024 14.4 8.5 0.8 9.5 1.8 3.3 3 0 0 3 3 3 0 Transposase zinc-ribbon domain zf-ZPR1 PF03367.8 CBZ08562.1 - 0.035 13.2 0.0 0.069 12.3 0.0 1.5 1 0 0 1 1 1 0 ZPR1 zinc-finger domain zf-NADH-PPase PF09297.6 CBZ08562.1 - 0.19 11.2 4.1 0.4 10.2 0.4 2.6 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-HC5HC2H PF13771.1 CBZ08562.1 - 0.22 11.6 3.2 4.1 7.6 0.2 2.8 3 0 0 3 3 3 0 PHD-like zinc-binding domain Zn-ribbon_8 PF09723.5 CBZ08562.1 - 0.83 9.6 5.9 27 4.8 0.4 3.2 3 0 0 3 3 3 0 Zinc ribbon domain DUF4187 PF13821.1 CBZ08562.1 - 3.3 7.3 7.3 5.9 6.5 1.8 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4187) zf-C3HC4_3 PF13920.1 CBZ08562.1 - 4.1 7.1 6.9 1.2 8.8 0.1 2.6 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_2 PF13240.1 CBZ08562.1 - 5.9 6.5 11.8 3.7 7.1 0.0 3.2 3 0 0 3 3 3 0 zinc-ribbon domain GTP_EFTU PF00009.22 CBZ08563.1 - 1.3e-54 184.4 0.1 2.2e-54 183.7 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBZ08563.1 - 9.9e-20 70.5 0.3 2.8e-18 65.9 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CBZ08563.1 - 5e-09 36.1 0.9 1.3e-08 34.8 0.6 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CBZ08563.1 - 0.0023 17.8 0.0 0.0047 16.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 CBZ08563.1 - 0.021 14.2 0.8 2.4 7.6 0.1 2.5 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 CBZ08563.1 - 0.042 14.3 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein GTP_EFTU_D4 PF14578.1 CBZ08563.1 - 0.054 13.1 0.2 0.054 13.1 0.2 2.1 2 0 0 2 2 2 0 Elongation factor Tu domain 4 AAA_29 PF13555.1 CBZ08563.1 - 0.1 12.1 0.1 0.35 10.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Ras PF00071.17 CBZ08564.1 - 5.9e-54 181.8 1.6 7.3e-53 178.2 1.1 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 CBZ08564.1 - 4.8e-21 75.4 0.1 9.8e-21 74.4 0.0 1.5 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 CBZ08564.1 - 1.9e-12 46.7 0.0 2.4e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBZ08564.1 - 4.4e-09 35.8 0.0 5.7e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBZ08564.1 - 3.2e-05 23.4 0.2 0.00067 19.1 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBZ08564.1 - 4.5e-05 23.3 0.0 6.8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.9 CBZ08564.1 - 0.0016 18.1 0.0 0.0089 15.7 0.0 2.0 1 1 1 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 CBZ08564.1 - 0.002 18.1 0.1 0.0028 17.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CBZ08564.1 - 0.0027 17.8 0.0 0.0051 16.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 CBZ08564.1 - 0.0067 16.0 0.0 0.015 14.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 CBZ08564.1 - 0.012 15.3 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 NTPase cobW PF02492.14 CBZ08564.1 - 0.016 14.6 0.1 3.4 7.0 0.0 2.3 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 CBZ08564.1 - 0.017 14.6 0.0 0.031 13.7 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain DUF258 PF03193.11 CBZ08564.1 - 0.021 13.9 0.1 0.042 13.0 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 CBZ08564.1 - 0.027 14.1 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Arch_ATPase PF01637.13 CBZ08564.1 - 0.033 13.8 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_25 PF13481.1 CBZ08564.1 - 0.046 13.1 0.0 0.14 11.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CBZ08564.1 - 0.051 13.2 0.0 0.076 12.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 CBZ08564.1 - 0.059 12.8 0.1 0.2 11.1 0.0 2.0 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 CBZ08564.1 - 0.065 13.4 0.0 0.26 11.4 0.0 2.0 1 1 0 1 1 1 0 RNA helicase ATP_bind_1 PF03029.12 CBZ08564.1 - 0.065 12.7 0.0 1.3 8.5 0.0 2.3 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA PF00004.24 CBZ08564.1 - 0.11 12.6 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PRK PF00485.13 CBZ08564.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.17 CBZ08564.1 - 0.12 11.1 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain HSP70 PF00012.15 CBZ08566.1 - 1.4e-108 363.4 6.2 1.1e-102 343.9 0.0 2.9 3 0 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.8 CBZ08566.1 - 0.00072 18.2 0.0 0.0052 15.4 0.0 2.3 1 1 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.11 CBZ08566.1 - 0.00086 18.9 0.0 0.0022 17.6 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Inhibitor_G39P PF11417.3 CBZ08568.1 - 0.087 12.8 0.0 19 5.3 0.0 2.7 3 0 0 3 3 3 0 Loader and inhibitor of phage G40P Ribosomal_L36e PF01158.13 CBZ08568.1 - 0.2 11.5 0.0 0.4 10.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L36e Histone PF00125.19 CBZ08569.1 - 2.6e-16 59.4 1.2 3.4e-16 59.1 0.8 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBZ08569.1 - 0.0023 17.9 0.3 0.0044 17.0 0.2 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DNA_photolyase PF00875.13 CBZ08569.1 - 0.011 15.4 0.1 0.013 15.2 0.0 1.0 1 0 0 1 1 1 0 DNA photolyase IpaB_EvcA PF03278.8 CBZ08569.1 - 0.053 12.7 0.1 0.067 12.4 0.0 1.1 1 0 0 1 1 1 0 IpaB/EvcA family Ribosomal_S5_C PF03719.10 CBZ08570.1 - 2e-24 84.6 0.0 3.3e-24 83.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 CBZ08570.1 - 2.2e-21 75.3 0.3 3.6e-21 74.6 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain SH3_9 PF14604.1 CBZ08571.1 - 3e-08 33.0 0.0 6.1e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CBZ08571.1 - 7.3e-07 28.4 0.0 1.4e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBZ08571.1 - 0.0019 17.6 0.0 0.0043 16.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain DUF3328 PF11807.3 CBZ08571.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) RCR PF12273.3 CBZ08571.1 - 0.92 10.0 5.9 1 9.9 0.0 2.5 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red DnaJ PF00226.26 CBZ08572.1 - 1.4e-20 72.7 0.5 1.4e-20 72.7 0.3 2.6 2 0 0 2 2 2 1 DnaJ domain DUF865 PF05906.6 CBZ08572.1 - 0.15 11.7 0.5 0.27 10.8 0.3 1.4 1 0 0 1 1 1 0 Herpesvirus-7 repeat of unknown function (DUF865) DnaJ PF00226.26 CBZ08573.1 - 0.39 10.4 4.8 3.9 7.2 0.3 3.3 3 1 0 3 3 3 0 DnaJ domain Fibrillarin PF01269.12 CBZ08574.1 - 4.3e-102 339.8 0.0 4.9e-102 339.6 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 CBZ08574.1 - 7.1e-07 28.9 0.0 9.9e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Clathrin_lg_ch PF01086.12 CBZ08575.1 - 4e-07 30.1 2.1 5.8e-07 29.6 1.5 1.2 1 0 0 1 1 1 1 Clathrin light chain SNARE PF05739.14 CBZ08576.1 - 2.1e-08 33.7 4.1 9.5e-08 31.6 2.7 2.1 2 0 0 2 2 2 1 SNARE domain PspA_IM30 PF04012.7 CBZ08576.1 - 0.00024 20.5 0.5 0.00048 19.5 0.2 1.6 1 1 0 1 1 1 1 PspA/IM30 family Med9 PF07544.8 CBZ08576.1 - 0.013 15.1 5.5 0.13 12.0 0.4 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Vac_Fusion PF02346.11 CBZ08576.1 - 0.049 13.0 1.5 5.2 6.5 0.1 3.1 3 0 0 3 3 3 0 Chordopoxvirus fusion protein ORC4_C PF14629.1 CBZ08576.1 - 0.07 12.4 0.4 3.2 7.1 0.0 2.3 2 1 0 2 2 2 0 Origin recognition complex (ORC) subunit 4 C-terminus Cep57_MT_bd PF06657.8 CBZ08576.1 - 0.47 10.4 7.1 0.52 10.2 1.2 2.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 COG2 PF06148.6 CBZ08576.1 - 0.75 9.6 4.6 10 5.9 0.1 2.7 2 2 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Sec2p PF06428.6 CBZ08576.1 - 0.89 9.4 6.4 0.45 10.4 0.2 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p DUF745 PF05335.8 CBZ08576.1 - 2.2 7.7 7.6 3.8 6.9 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) FliJ PF02050.11 CBZ08576.1 - 6.1 6.9 14.8 2.1 8.4 1.8 2.9 2 1 0 2 2 2 0 Flagellar FliJ protein DER1 PF04511.10 CBZ08577.1 - 2.2e-30 105.6 5.1 2.6e-30 105.4 3.5 1.0 1 0 0 1 1 1 1 Der1-like family Pkinase PF00069.20 CBZ08578.1 - 6.3e-54 182.8 0.0 1e-53 182.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ08578.1 - 6.2e-25 87.7 0.0 3e-20 72.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase CAP_GLY PF01302.20 CBZ08578.1 - 7.8e-17 60.7 0.7 1.7e-16 59.6 0.5 1.6 1 0 0 1 1 1 1 CAP-Gly domain Kinase-like PF14531.1 CBZ08578.1 - 5.7e-06 25.5 0.0 0.0055 15.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase PF00069.20 CBZ08579.1 - 5e-57 193.0 0.0 5.7e-57 192.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ08579.1 - 8.1e-34 116.8 0.0 9.6e-34 116.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.11 CBZ08579.1 - 0.023 14.6 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 ABC1 family Peptidase_M24 PF00557.19 CBZ08580.1 - 5.2e-29 101.3 1.4 6.9e-29 100.9 0.9 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Pkinase PF00069.20 CBZ08582.1 - 1.4e-71 240.7 0.0 1.7e-71 240.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ08582.1 - 9.7e-33 113.3 0.1 2e-31 109.0 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ08582.1 - 0.051 13.3 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4319 PF14203.1 CBZ08582.1 - 0.082 12.4 0.1 0.19 11.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4319) HTH_3 PF01381.17 CBZ08583.1 - 4.8e-11 42.3 0.2 8.6e-11 41.5 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix MBF1 PF08523.5 CBZ08583.1 - 5.8e-06 26.2 4.0 5.8e-06 26.2 2.8 2.0 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_31 PF13560.1 CBZ08583.1 - 0.0012 19.0 0.6 0.0023 18.0 0.4 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 CBZ08583.1 - 0.0017 18.3 0.1 0.0028 17.6 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Spectrin PF00435.16 CBZ08583.1 - 0.45 10.8 4.5 0.7 10.2 3.1 1.3 1 0 0 1 1 1 0 Spectrin repeat Mito_carr PF00153.22 CBZ08584.1 - 2.6e-67 222.5 3.5 2.3e-23 81.7 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein TBCC PF07986.7 CBZ08585.1 - 6.1e-27 93.4 9.4 7e-09 35.1 0.0 3.4 3 0 0 3 3 3 3 Tubulin binding cofactor C Pkinase PF00069.20 CBZ08585.1 - 0.29 10.2 0.0 4.5 6.3 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain Phage-A118_gp45 PF10653.4 CBZ08585.1 - 0.45 10.4 0.0 0.94 9.3 0.0 1.4 1 0 0 1 1 1 0 Protein gp45 of Bacteriophage A118 CAP_C PF08603.6 CBZ08585.1 - 0.69 9.2 0.4 1.4 8.2 0.3 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal Atg8 PF02991.11 CBZ08586.1 - 1e-10 41.4 0.0 1.4e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like ExbD PF02472.11 CBZ08586.1 - 0.07 13.1 0.0 0.083 12.8 0.0 1.1 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR AMP-binding PF00501.23 CBZ08587.1 - 1.1e-86 290.8 1.0 1.5e-86 290.4 0.7 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CBZ08587.1 - 1.1e-09 39.1 0.1 3.9e-09 37.3 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 CBZ08588.1 - 6.1e-87 291.7 1.0 7.2e-87 291.4 0.7 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CBZ08588.1 - 8.3e-10 39.4 0.1 2.8e-09 37.8 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MBOAT PF03062.14 CBZ08591.1 - 4.2e-31 108.2 16.4 6.6e-31 107.6 11.4 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT PF03062.14 CBZ08592.1 - 2.8e-30 105.5 21.9 6e-30 104.4 15.2 1.5 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT PF03062.14 CBZ08593.1 - 1.9e-30 106.1 22.3 3e-30 105.4 15.5 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT PF03062.14 CBZ08594.1 - 5.6e-30 104.5 21.9 8.8e-30 103.9 15.2 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT PF03062.14 CBZ08595.1 - 3.5e-30 105.2 22.4 7.1e-30 104.2 15.5 1.5 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT PF03062.14 CBZ08596.1 - 1.9e-30 106.1 20.1 3.9e-30 105.0 13.9 1.5 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family LRR_4 PF12799.2 CBZ08597.1 - 1.4e-25 88.3 0.0 1.2e-06 28.0 0.1 7.9 4 2 1 8 8 8 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ08597.1 - 3.9e-12 45.7 5.1 0.0008 19.1 0.3 6.5 3 1 7 10 10 10 8 Leucine rich repeat LRR_1 PF00560.28 CBZ08597.1 - 2.5e-09 35.8 18.3 6.4 7.2 0.0 11.3 11 2 0 11 11 11 3 Leucine Rich Repeat LRR_6 PF13516.1 CBZ08597.1 - 1.3e-06 27.8 5.9 0.51 10.5 0.0 8.0 8 2 1 9 9 9 2 Leucine Rich repeat LRR_7 PF13504.1 CBZ08597.1 - 0.24 11.7 19.5 28 5.5 0.0 9.7 10 1 0 10 10 10 0 Leucine rich repeat RNA_pol_Rpb2_6 PF00562.23 CBZ08599.1 - 4.1e-114 381.3 0.0 6e-114 380.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CBZ08599.1 - 1.6e-45 154.5 1.5 2.4e-45 153.9 1.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 CBZ08599.1 - 1.6e-28 98.7 0.1 3.9e-28 97.5 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 CBZ08599.1 - 4.2e-21 75.2 0.2 8.3e-21 74.2 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 CBZ08599.1 - 2.3e-19 68.9 1.2 2.3e-19 68.9 0.8 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 CBZ08599.1 - 5.1e-19 67.8 0.0 1e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 CBZ08599.1 - 1.3e-10 41.1 0.2 3.1e-10 39.8 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Chlorophyllase PF07224.6 CBZ08599.1 - 0.017 13.9 0.0 0.031 13.0 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase PGK PF00162.14 CBZ08601.1 - 1.5e-152 507.6 0.0 1.7e-152 507.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PGK PF00162.14 CBZ08602.1 - 9.2e-153 508.3 0.0 1e-152 508.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DnaB_2 PF07261.6 CBZ08605.1 - 0.11 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Replication initiation and membrane attachment Peptidase_M20 PF01546.23 CBZ08606.1 - 5.8e-29 100.9 0.1 7e-29 100.6 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CBZ08606.1 - 9.8e-10 38.1 0.0 2.5e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 CBZ08606.1 - 0.061 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 MFS_1 PF07690.11 CBZ08608.1 - 2.2e-19 69.3 27.7 2.2e-19 69.3 19.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pribosyltran PF00156.22 CBZ08610.1 - 2.1e-13 50.0 0.0 3e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyltran PF00156.22 CBZ08611.1 - 2e-14 53.3 0.0 3.3e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain HEAT PF02985.17 CBZ08613.1 - 0.0004 20.2 0.3 0.17 12.0 0.0 4.0 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.1 CBZ08613.1 - 0.11 12.7 7.8 0.51 10.6 0.5 4.0 3 1 2 5 5 5 0 HEAT repeats HEAT_EZ PF13513.1 CBZ08613.1 - 0.12 12.8 6.5 3.6 8.1 0.4 3.3 2 0 0 2 2 2 0 HEAT-like repeat HEAT_2 PF13646.1 CBZ08614.1 - 3.1e-11 43.4 0.3 0.0006 20.0 0.0 4.2 3 1 0 3 3 3 2 HEAT repeats DUF4042 PF13251.1 CBZ08614.1 - 3.2e-08 33.2 1.1 7.8e-05 22.2 0.1 4.7 4 1 0 4 4 4 1 Domain of unknown function (DUF4042) HEAT PF02985.17 CBZ08614.1 - 6.3e-08 32.0 2.8 0.49 10.6 0.0 6.5 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 CBZ08614.1 - 5.9e-07 29.7 17.0 0.00084 19.7 0.1 7.1 6 2 1 7 7 7 2 HEAT-like repeat Adaptin_N PF01602.15 CBZ08614.1 - 0.053 11.8 0.0 0.097 10.9 0.0 1.4 1 0 0 1 1 1 0 Adaptin N terminal region Ipi1_N PF12333.3 CBZ08614.1 - 0.099 12.6 0.0 1.1 9.2 0.0 2.8 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation ABC_tran PF00005.22 CBZ08615.1 - 3.1e-06 27.5 0.0 5.9e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 CBZ08615.1 - 1.4e-05 24.3 15.5 2.7e-05 23.4 10.7 1.4 1 0 0 1 1 1 1 ABC-2 type transporter PDR_CDR PF06422.7 CBZ08615.1 - 0.06 13.0 0.0 0.23 11.1 0.0 2.0 1 0 0 1 1 1 0 CDR ABC transporter UPF0506 PF11703.3 CBZ08615.1 - 0.18 11.7 1.4 0.63 10.0 1.0 1.9 1 0 0 1 1 1 0 UPF0506 zf-DHHC PF01529.15 CBZ08615.1 - 1.4 8.2 4.4 1.9 7.8 0.1 2.4 2 0 0 2 2 2 0 DHHC palmitoyltransferase ATP1G1_PLM_MAT8 PF02038.11 CBZ08616.1 - 0.024 13.6 0.0 0.036 13.0 0.0 1.3 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family DUF4499 PF14934.1 CBZ08617.1 - 7.8e-07 28.9 2.4 1.4e-06 28.1 1.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) MutS_V PF00488.16 CBZ08618.1 - 3e-33 115.2 0.0 6.2e-33 114.1 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CBZ08618.1 - 1e-15 58.1 0.0 2.7e-15 56.7 0.0 1.7 1 1 0 1 1 1 1 MutS domain III MutS_II PF05188.12 CBZ08618.1 - 0.0009 19.3 0.1 0.0018 18.3 0.1 1.4 1 0 0 1 1 1 1 MutS domain II AAA_16 PF13191.1 CBZ08618.1 - 0.0015 18.5 2.8 0.0041 17.1 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 CBZ08618.1 - 0.0056 16.6 0.0 0.0082 16.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CBZ08618.1 - 0.0095 15.9 0.2 0.19 11.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 CBZ08618.1 - 0.025 14.4 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CBZ08618.1 - 0.071 13.2 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CBZ08618.1 - 0.098 12.9 0.1 0.22 11.7 0.1 1.5 1 0 0 1 1 1 0 ABC transporter MutS_IV PF05190.13 CBZ08618.1 - 0.16 12.1 0.0 0.47 10.6 0.0 1.8 1 0 0 1 1 1 0 MutS family domain IV AAA PF00004.24 CBZ08618.1 - 0.17 12.1 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 CBZ08618.1 - 0.26 10.9 0.0 0.45 10.1 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_23 PF13476.1 CBZ08618.1 - 0.29 11.4 0.1 0.51 10.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CBZ08618.1 - 0.34 11.7 0.0 0.69 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain CAP_C PF08603.6 CBZ08619.1 - 1.1e-19 70.3 0.1 1.7e-19 69.7 0.1 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 CBZ08619.1 - 0.0029 16.9 0.2 0.0061 15.9 0.1 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_N PF01213.14 CBZ08619.1 - 0.009 15.3 0.0 0.009 15.3 0.0 2.5 3 0 0 3 3 3 1 Adenylate cyclase associated (CAP) N terminal tRNA-synt_2 PF00152.15 CBZ08620.1 - 3.3e-67 226.6 0.0 7.2e-67 225.5 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CBZ08620.1 - 1.8e-08 34.1 0.0 3.3e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CBZ08620.1 - 2.2e-06 27.0 0.1 0.0062 15.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Nro1 PF12753.2 CBZ08622.1 - 0.19 10.6 0.0 0.29 10.0 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 tRNA_edit PF04073.10 CBZ08623.1 - 7.5e-08 32.2 0.0 1.6e-07 31.1 0.0 1.5 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain Sugarporin_N PF11471.3 CBZ08623.1 - 0.0012 18.4 0.0 0.0053 16.3 0.0 2.1 2 0 0 2 2 2 1 Maltoporin periplasmic N-terminal extension DUF3138 PF11336.3 CBZ08623.1 - 0.3 9.2 1.0 0.42 8.7 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Histone PF00125.19 CBZ08624.1 - 4.5e-16 58.7 0.0 6.2e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone PF00125.19 CBZ08625.1 - 4.5e-16 58.7 0.0 6.2e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PDCD2_C PF04194.8 CBZ08627.1 - 1.5e-30 105.9 5.1 2.2e-23 82.6 0.1 2.9 3 0 0 3 3 3 2 Programmed cell death protein 2, C-terminal putative domain DUF4554 PF15091.1 CBZ08629.1 - 0.097 11.3 5.5 0.17 10.5 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Clathrin PF00637.15 CBZ08630.1 - 6e-12 45.3 20.0 0.019 14.5 0.0 9.6 5 3 5 11 11 11 2 Region in Clathrin and VPS WD40 PF00400.27 CBZ08630.1 - 1.3e-09 37.5 0.7 0.25 11.2 0.1 6.0 7 0 0 7 7 6 2 WD domain, G-beta repeat TPR_4 PF07721.9 CBZ08630.1 - 1e-05 25.4 10.4 0.27 11.7 0.0 8.4 7 1 1 8 8 8 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.9 CBZ08630.1 - 0.00012 21.0 12.6 0.0016 17.3 0.7 5.5 4 2 1 6 6 6 1 Coatomer WD associated region PPR PF01535.15 CBZ08630.1 - 0.0017 18.2 10.3 4.7 7.4 0.4 7.6 7 1 1 8 8 7 1 PPR repeat Apc3 PF12895.2 CBZ08630.1 - 0.0076 16.3 28.4 0.23 11.6 0.0 7.9 5 3 3 8 8 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 CBZ08630.1 - 0.018 14.9 39.5 1 9.3 0.3 10.4 10 1 1 11 11 11 0 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ08630.1 - 0.16 11.9 41.7 0.19 11.6 0.1 11.2 12 0 0 12 12 11 0 Tetratricopeptide repeat zf-ribbon_3 PF13248.1 CBZ08630.1 - 0.19 11.0 1.2 0.52 9.5 0.8 1.8 1 0 0 1 1 1 0 zinc-ribbon domain TPR_19 PF14559.1 CBZ08630.1 - 0.26 11.6 0.0 0.26 11.6 0.0 8.6 10 4 2 12 12 11 0 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ08630.1 - 0.33 10.8 30.2 1.9 8.5 0.0 11.2 12 3 2 14 14 14 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ08630.1 - 3.9 7.2 37.5 5.2 6.8 0.1 10.9 11 1 1 12 12 12 0 Tetratricopeptide repeat PPR_3 PF13812.1 CBZ08630.1 - 4.7 7.7 16.5 15 6.2 0.0 8.2 8 1 1 9 9 9 0 Pentatricopeptide repeat domain TPR_14 PF13428.1 CBZ08630.1 - 6.4 7.7 52.4 6 7.7 0.1 15.8 14 7 4 18 18 17 0 Tetratricopeptide repeat TPR_10 PF13374.1 CBZ08630.1 - 8.2 6.5 10.9 2.7 8.0 0.1 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF334 PF03904.8 CBZ08632.1 - 1.2 8.4 0.4 2.5 7.3 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Tubulin PF00091.20 CBZ08633.1 - 1.1e-72 244.3 0.0 1.5e-72 243.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBZ08633.1 - 6.2e-20 71.5 0.0 1e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.1 CBZ08633.1 - 0.01 14.7 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Tubulin like Misat_Tub_SegII PF10644.4 CBZ08633.1 - 0.088 12.8 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain Ax_dynein_light PF10211.4 CBZ08634.1 - 2.1e-49 167.9 2.8 2.1e-49 167.9 1.9 1.5 2 0 0 2 2 2 1 Axonemal dynein light chain CCDC66 PF15236.1 CBZ08635.1 - 8.6e-07 28.6 36.1 8.6e-07 28.6 25.0 1.6 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 66 IncA PF04156.9 CBZ08635.1 - 5.8 6.4 15.0 13 5.3 10.4 1.5 1 0 0 1 1 1 0 IncA protein Kinesin PF00225.18 CBZ08636.1 - 9.8e-86 287.4 0.3 1.8e-85 286.5 0.2 1.4 1 0 0 1 1 1 1 Kinesin motor domain Pox_A_type_inc PF04508.7 CBZ08636.1 - 0.41 10.5 14.1 0.61 10.0 0.4 4.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Ribosomal_L6 PF00347.18 CBZ08637.1 - 6.1e-29 100.3 3.8 7.3e-16 58.4 0.4 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Hormone_2 PF00123.15 CBZ08637.1 - 0.12 12.2 0.0 30 4.5 0.0 3.1 3 0 0 3 3 3 0 Peptide hormone YbbR PF07949.7 CBZ08637.1 - 1 9.5 4.0 5.1 7.2 0.2 2.7 2 2 0 2 2 2 0 YbbR-like protein Ribosom_S12_S23 PF00164.20 CBZ08638.1 - 4.1e-39 132.7 1.0 6.4e-39 132.1 0.7 1.3 1 1 0 1 1 1 1 Ribosomal protein S12/S23 Ribosom_S12_S23 PF00164.20 CBZ08639.1 - 4.1e-39 132.7 1.0 6.4e-39 132.1 0.7 1.3 1 1 0 1 1 1 1 Ribosomal protein S12/S23 Pkinase PF00069.20 CBZ08640.1 - 1.7e-74 250.2 0.0 1.9e-74 250.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ08640.1 - 4.2e-34 117.7 0.0 5.3e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ08640.1 - 0.0012 18.6 0.4 0.095 12.4 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CBZ08640.1 - 0.0053 15.8 0.4 0.011 14.8 0.3 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBZ08640.1 - 0.0057 15.6 0.0 0.065 12.1 0.0 2.1 1 1 0 2 2 2 1 Kinase-like Cpn60_TCP1 PF00118.19 CBZ08641.1 - 4.4e-137 457.6 7.3 5.1e-137 457.4 5.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Colicin PF01024.14 CBZ08641.1 - 0.022 14.3 0.1 0.053 13.0 0.1 1.7 1 0 0 1 1 1 0 Colicin pore forming domain Tau95 PF09734.4 CBZ08642.1 - 1.2e-82 277.7 0.0 1.7e-82 277.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit IQ PF00612.22 CBZ08643.1 - 4.3e-10 38.3 214.7 3.6e-05 23.0 0.1 25.3 25 1 2 27 27 27 14 IQ calmodulin-binding motif TPR_1 PF00515.23 CBZ08643.1 - 9.5e-06 25.0 0.0 0.8 9.4 0.0 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat WD40 PF00400.27 CBZ08644.1 - 2.1e-15 55.9 14.4 8.2e-05 22.3 0.2 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 CBZ08644.1 - 0.00071 17.8 0.5 0.0016 16.6 0.0 1.7 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Ribosomal_L13 PF00572.13 CBZ08644.1 - 0.0026 17.8 0.2 0.25 11.4 0.1 2.2 2 0 0 2 2 2 1 Ribosomal protein L13 Nbas_N PF15492.1 CBZ08644.1 - 0.046 12.8 0.0 1.3 8.0 0.0 2.4 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Cyt-b5 PF00173.23 CBZ08645.1 - 4.6e-05 23.1 0.0 6.9e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ribosomal_L5_C PF00673.16 CBZ08647.1 - 3.2e-22 78.0 0.0 5.5e-22 77.3 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 CBZ08647.1 - 8.9e-17 60.6 0.4 3.2e-16 58.8 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L5 SET PF00856.23 CBZ08648.1 - 4.9e-05 23.6 0.0 7.8e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 SET domain zf-NF-X1 PF01422.12 CBZ08650.1 - 3.8e-10 39.5 58.7 4.8e-06 26.3 9.2 15.0 17 1 0 17 17 17 8 NF-X1 type zinc finger R3H PF01424.17 CBZ08650.1 - 5.5e-10 38.8 0.0 1.1e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 R3H domain CTDII PF01556.13 CBZ08652.1 - 9.7e-22 76.6 0.1 1.5e-20 72.8 0.0 2.8 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CBZ08652.1 - 3.9e-14 52.4 13.6 1.2e-13 50.8 9.4 1.9 1 1 1 2 2 2 2 DnaJ central domain HypA PF01155.14 CBZ08652.1 - 0.00046 19.8 6.6 0.05 13.2 1.3 2.5 1 1 1 2 2 2 2 Hydrogenase expression/synthesis hypA family CART PF06373.6 CBZ08652.1 - 0.017 15.0 1.3 0.039 13.9 0.4 2.0 2 0 0 2 2 2 0 Cocaine and amphetamine regulated transcript protein (CART) Lar_restr_allev PF14354.1 CBZ08652.1 - 0.054 13.7 5.4 0.18 12.1 0.8 3.1 1 1 1 2 2 2 0 Restriction alleviation protein Lar Herpes_UL16 PF03044.9 CBZ08652.1 - 0.063 12.2 1.9 0.098 11.6 1.3 1.2 1 0 0 1 1 1 0 Herpesvirus UL16/UL94 family DUF3556 PF12077.3 CBZ08652.1 - 0.13 10.2 0.1 0.16 9.9 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein of unknown function (DUF3556) DZR PF12773.2 CBZ08652.1 - 0.71 9.7 8.0 1.8 8.4 0.8 2.5 1 1 1 2 2 2 0 Double zinc ribbon Pox_MCEL PF03291.11 CBZ08653.1 - 1e-43 149.5 0.0 1.2e-43 149.3 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme mRNA_cap_enzyme PF01331.14 CBZ08653.1 - 9e-08 32.0 0.0 0.0059 16.3 0.0 2.5 2 0 0 2 2 2 2 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 CBZ08653.1 - 1.2e-06 28.8 0.0 3.4e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain Methyltransf_18 PF12847.2 CBZ08653.1 - 0.0001 22.8 0.0 0.00077 20.0 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ08653.1 - 0.0028 18.0 0.1 0.0097 16.2 0.1 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBZ08653.1 - 0.0051 16.8 0.0 0.0051 16.8 0.0 3.1 5 1 0 5 5 5 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ08653.1 - 0.039 13.5 0.0 0.084 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain GATase PF00117.23 CBZ08655.1 - 2.6e-38 131.4 0.0 4.6e-38 130.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 CBZ08655.1 - 2e-28 97.9 0.0 2.5e-16 59.1 0.0 2.8 2 0 0 2 2 2 2 GMP synthase C terminal domain Peptidase_C26 PF07722.8 CBZ08655.1 - 9.9e-16 57.8 0.0 4.8e-15 55.5 0.0 2.3 1 1 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.12 CBZ08655.1 - 1.4e-09 37.1 0.1 0.00017 20.6 0.0 2.4 2 0 0 2 2 2 2 NAD synthase QueC PF06508.8 CBZ08655.1 - 2.9e-05 23.4 0.0 0.00018 20.8 0.0 2.0 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC ThiI PF02568.9 CBZ08655.1 - 0.00086 18.8 0.1 0.0046 16.4 0.0 2.2 3 0 0 3 3 3 1 Thiamine biosynthesis protein (ThiI) GATase_3 PF07685.9 CBZ08655.1 - 0.001 18.6 0.1 0.0019 17.7 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain PAPS_reduct PF01507.14 CBZ08655.1 - 0.0018 18.0 0.0 0.0032 17.2 0.0 1.5 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Arginosuc_synth PF00764.14 CBZ08655.1 - 0.0052 15.8 0.0 0.0079 15.2 0.0 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase ATP_bind_3 PF01171.15 CBZ08655.1 - 0.0063 16.0 0.1 0.03 13.8 0.1 2.0 2 0 0 2 2 2 1 PP-loop family Asn_synthase PF00733.16 CBZ08655.1 - 0.0097 15.4 0.1 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.11 CBZ08655.1 - 0.011 14.2 0.1 0.041 12.4 0.1 1.8 2 0 0 2 2 2 0 tRNA methyl transferase DUF1049 PF06305.6 CBZ08656.1 - 0.13 11.8 0.1 0.32 10.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Herpes_gE PF02480.11 CBZ08656.1 - 0.22 9.7 0.0 0.43 8.7 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF1049 PF06305.6 CBZ08657.1 - 0.13 11.8 0.1 0.32 10.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Herpes_gE PF02480.11 CBZ08657.1 - 0.22 9.7 0.0 0.44 8.7 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E zf-C3HC4_3 PF13920.1 CBZ08659.1 - 1.3e-09 37.5 10.8 2.3e-09 36.7 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ08659.1 - 0.06 13.0 10.1 0.11 12.2 7.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain WD40 PF00400.27 CBZ08660.1 - 1.7e-26 91.1 16.7 2.5e-05 23.9 0.2 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CBZ08660.1 - 0.0045 16.4 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.6 CBZ08660.1 - 0.19 10.4 0.5 18 3.9 0.2 2.7 2 1 0 2 2 2 0 Nup133 N terminal like MORN PF02493.15 CBZ08662.1 - 4e-05 23.0 13.3 0.14 11.9 0.1 3.5 3 0 0 3 3 3 3 MORN repeat Ribonuc_red_sm PF00268.16 CBZ08664.1 - 2.5e-111 371.1 0.1 3e-111 370.9 0.1 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Atg8 PF02991.11 CBZ08665.1 - 6.1e-12 45.4 0.0 2.4e-11 43.5 0.0 1.7 2 0 0 2 2 2 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 CBZ08665.1 - 0.00055 20.0 0.0 0.00093 19.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 COMP PF11598.3 CBZ08666.1 - 4.2e-16 58.7 47.1 0.33 11.0 0.1 10.0 10 0 0 10 10 10 9 Cartilage oligomeric matrix protein TMF_DNA_bd PF12329.3 CBZ08666.1 - 2.9e-05 23.7 64.6 0.0043 16.8 1.7 9.9 4 2 6 10 10 10 8 TATA element modulatory factor 1 DNA binding Halo_GVPC PF05465.8 CBZ08666.1 - 0.00042 20.1 57.2 1.8 8.5 0.5 9.8 9 0 0 9 9 9 6 Halobacterial gas vesicle protein C (GVPC) repeat Fib_alpha PF08702.5 CBZ08666.1 - 9.2 6.3 45.6 8.3 6.5 0.5 9.3 4 2 5 9 9 9 0 Fibrinogen alpha/beta chain family Methyltransf_28 PF02636.12 CBZ08667.1 - 2.2e-34 119.0 0.1 3e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 CBZ08667.1 - 0.00036 19.6 0.0 0.00065 18.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.2 CBZ08667.1 - 0.00044 20.7 0.0 0.0014 19.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ08667.1 - 0.0011 18.6 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBZ08667.1 - 0.0041 17.1 0.1 0.011 15.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ08667.1 - 0.012 16.0 0.0 0.024 15.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.11 CBZ08667.1 - 0.024 13.5 0.0 0.038 12.9 0.0 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_32 PF13679.1 CBZ08667.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain zf-DHHC PF01529.15 CBZ08668.1 - 2.1e-29 102.1 1.8 3.2e-29 101.5 1.3 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase polyprenyl_synt PF00348.12 CBZ08669.1 - 1.4e-52 178.1 0.1 1.8e-52 177.7 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Erythro_esteras PF05139.9 CBZ08669.1 - 0.0058 15.8 0.0 0.0095 15.1 0.0 1.2 1 0 0 1 1 1 1 Erythromycin esterase Reo_sigmaC PF04582.7 CBZ08670.1 - 0.16 11.1 23.7 1.1 8.3 1.0 4.2 1 1 4 5 5 5 0 Reovirus sigma C capsid protein Cas_GSU0053 PF09617.5 CBZ08670.1 - 0.38 10.5 3.6 0.34 10.6 0.5 2.1 2 0 0 2 2 2 0 CRISPR-associated protein GSU0053 (Cas_GSU0053) Spc7 PF08317.6 CBZ08670.1 - 0.66 8.5 58.9 0.067 11.8 12.4 3.4 1 1 1 3 3 3 0 Spc7 kinetochore protein DUF948 PF06103.6 CBZ08670.1 - 7.2 6.5 29.8 0.72 9.7 2.6 5.2 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) Flu_NS2 PF00601.14 CBZ08670.1 - 7.6 6.8 17.6 0.3 11.3 0.5 4.3 3 1 1 4 4 4 0 Influenza non-structural protein (NS2) Ribosomal_L28e PF01778.12 CBZ08671.1 - 4.8e-28 97.8 0.6 7.1e-28 97.3 0.0 1.6 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 CBZ08671.1 - 7.9e-14 51.5 21.2 7.9e-14 51.5 14.7 2.3 2 0 0 2 2 2 1 Mak16 protein C-terminal region Exonuc_VII_L PF02601.10 CBZ08671.1 - 0.34 10.0 6.4 0.45 9.6 4.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit RNase_H2-Ydr279 PF09468.5 CBZ08671.1 - 1.2 8.3 7.3 1.7 7.7 5.1 1.3 1 1 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF1786 PF08735.5 CBZ08672.1 - 0.057 12.5 0.0 0.086 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative pyruvate format-lyase activating enzyme (DUF1786) Peptidase_M3 PF01432.15 CBZ08673.1 - 2.8e-54 184.9 0.0 3e-54 184.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M3 DUF2370 PF10176.4 CBZ08674.1 - 0.16 11.2 4.5 0.13 11.6 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) XRN_N PF03159.13 CBZ08676.1 - 5.2e-45 153.6 0.0 1.2e-44 152.4 0.0 1.7 1 1 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus GFO_IDH_MocA PF01408.17 CBZ08677.1 - 3.1e-16 59.9 0.2 5.1e-16 59.2 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold LEA_4 PF02987.11 CBZ08680.1 - 4.1e-06 26.5 2.4 1e-05 25.3 1.5 1.9 1 1 0 1 1 1 1 Late embryogenesis abundant protein Apolipoprotein PF01442.13 CBZ08680.1 - 0.0016 18.0 0.1 0.0019 17.7 0.1 1.0 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 CBZ08680.1 - 0.0016 18.7 0.8 0.0021 18.4 0.6 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 CBZ08680.1 - 0.0094 16.2 2.9 0.013 15.8 2.0 1.2 1 0 0 1 1 1 1 YtxH-like protein Tape_meas_lam_C PF09718.5 CBZ08680.1 - 0.019 14.8 0.8 0.022 14.6 0.6 1.1 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) TPD52 PF04201.10 CBZ08680.1 - 0.039 13.6 0.7 0.043 13.5 0.5 1.0 1 0 0 1 1 1 0 Tumour protein D52 family Apo-CIII PF05778.7 CBZ08680.1 - 0.071 12.5 0.2 0.092 12.1 0.1 1.1 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) Perilipin PF03036.11 CBZ08680.1 - 0.082 11.7 0.2 0.079 11.7 0.2 1.2 1 0 0 1 1 1 0 Perilipin family FlgM PF04316.8 CBZ08680.1 - 0.11 12.5 3.9 3.6 7.6 0.3 2.1 1 1 1 2 2 2 0 Anti-sigma-28 factor, FlgM Phasin PF05597.6 CBZ08680.1 - 0.17 11.6 1.2 0.22 11.2 0.8 1.3 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Mit_KHE1 PF10173.4 CBZ08680.1 - 0.2 11.5 0.5 0.22 11.3 0.4 1.0 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related ATP-synt_B PF00430.13 CBZ08680.1 - 0.3 10.9 2.7 0.33 10.7 1.9 1.0 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) XhlA PF10779.4 CBZ08680.1 - 3.8 7.5 4.9 3.4 7.6 2.1 1.7 1 1 1 2 2 2 0 Haemolysin XhlA LEA_4 PF02987.11 CBZ08681.1 - 4.1e-06 26.5 2.4 1e-05 25.3 1.5 1.9 1 1 0 1 1 1 1 Late embryogenesis abundant protein Apolipoprotein PF01442.13 CBZ08681.1 - 0.0016 18.0 0.1 0.0019 17.7 0.1 1.0 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 CBZ08681.1 - 0.0016 18.7 0.8 0.0021 18.4 0.6 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 CBZ08681.1 - 0.0094 16.2 2.9 0.013 15.8 2.0 1.2 1 0 0 1 1 1 1 YtxH-like protein Tape_meas_lam_C PF09718.5 CBZ08681.1 - 0.019 14.8 0.8 0.022 14.6 0.6 1.1 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) TPD52 PF04201.10 CBZ08681.1 - 0.039 13.6 0.7 0.043 13.5 0.5 1.0 1 0 0 1 1 1 0 Tumour protein D52 family Apo-CIII PF05778.7 CBZ08681.1 - 0.071 12.5 0.2 0.092 12.1 0.1 1.1 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) Perilipin PF03036.11 CBZ08681.1 - 0.082 11.7 0.2 0.079 11.7 0.2 1.2 1 0 0 1 1 1 0 Perilipin family FlgM PF04316.8 CBZ08681.1 - 0.11 12.5 3.9 3.6 7.6 0.3 2.1 1 1 1 2 2 2 0 Anti-sigma-28 factor, FlgM Phasin PF05597.6 CBZ08681.1 - 0.17 11.6 1.2 0.22 11.2 0.8 1.3 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Mit_KHE1 PF10173.4 CBZ08681.1 - 0.2 11.5 0.5 0.22 11.3 0.4 1.0 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related ATP-synt_B PF00430.13 CBZ08681.1 - 0.3 10.9 2.7 0.33 10.7 1.9 1.0 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) XhlA PF10779.4 CBZ08681.1 - 3.8 7.5 4.9 3.4 7.6 2.1 1.7 1 1 1 2 2 2 0 Haemolysin XhlA NRDE-2 PF08424.5 CBZ08686.1 - 1.1e-06 27.7 0.2 0.0023 16.9 0.0 3.1 2 1 1 3 3 3 3 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 CBZ08686.1 - 0.13 12.9 22.4 16 6.4 0.1 8.8 7 1 2 9 9 9 0 Tetratricopeptide repeat Beach PF02138.13 CBZ08688.1 - 1.4e-86 290.3 0.0 2e-86 289.8 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain Nuc_deoxyrib_tr PF05014.10 CBZ08689.1 - 2.2e-28 98.4 0.0 2.8e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase DUF4406 PF14359.1 CBZ08689.1 - 0.00057 19.9 0.0 0.001 19.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4406) DUF3592 PF12158.3 CBZ08690.1 - 3.9e-05 23.4 0.1 5.6e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3592) Enkurin PF13864.1 CBZ08691.1 - 9.8e-23 80.2 2.8 1.5e-22 79.6 2.0 1.3 1 0 0 1 1 1 1 Calmodulin-binding CK2S PF15011.1 CBZ08691.1 - 0.052 13.3 1.4 1.3 8.8 0.1 2.1 1 1 1 2 2 2 0 Casein Kinase 2 substrate 7TMR-HDED PF07697.6 CBZ08691.1 - 0.066 12.9 1.1 0.098 12.3 0.7 1.2 1 0 0 1 1 1 0 7TM-HD extracellular DUF3367 PF11847.3 CBZ08691.1 - 0.078 10.9 0.1 0.11 10.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) PARP_regulatory PF01358.13 CBZ08692.1 - 6.1e-18 64.4 0.0 8.7e-18 63.9 0.0 1.1 1 0 0 1 1 1 1 Poly A polymerase regulatory subunit UPF0182 PF03699.8 CBZ08692.1 - 0.072 11.0 0.0 0.1 10.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) WD40 PF00400.27 CBZ08693.1 - 2.3e-08 33.5 19.6 0.0017 18.1 0.5 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat Ank_2 PF12796.2 CBZ08694.1 - 2.6e-45 152.6 7.1 5.9e-16 58.5 0.1 3.5 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CBZ08694.1 - 4.3e-43 143.0 6.7 1.1e-08 34.4 0.0 7.3 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.1 CBZ08694.1 - 9.9e-38 127.8 6.1 7.1e-08 32.7 0.0 5.4 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBZ08694.1 - 8.7e-35 117.9 7.3 3.7e-11 42.8 0.0 4.8 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ08694.1 - 2.5e-26 89.1 6.2 0.00013 21.8 0.0 7.7 8 0 0 8 8 8 6 Ankyrin repeat TPR_11 PF13414.1 CBZ08694.1 - 1.5e-16 59.7 6.6 3.7e-14 52.1 0.3 2.7 2 1 0 3 3 2 2 TPR repeat TPR_1 PF00515.23 CBZ08694.1 - 6.4e-09 35.0 1.5 0.034 13.7 0.0 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ08694.1 - 1.3e-05 24.7 6.1 0.4 10.7 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ08694.1 - 0.00029 20.8 1.0 0.41 10.9 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 CBZ08694.1 - 0.0014 18.6 0.8 0.0037 17.3 0.6 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CBZ08694.1 - 0.019 14.8 1.1 0.23 11.3 0.0 3.0 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF3775 PF12616.3 CBZ08694.1 - 0.071 12.9 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3775) PEX11 PF05648.9 CBZ08695.1 - 2.7e-10 39.9 1.3 1.3e-06 27.8 0.0 2.1 1 1 1 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) PalH PF08733.5 CBZ08695.1 - 0.01 14.6 0.0 0.012 14.4 0.0 1.1 1 0 0 1 1 1 0 PalH/RIM21 Phosducin PF02114.11 CBZ08697.1 - 1.3e-07 30.6 0.0 1.9e-07 30.0 0.0 1.3 1 1 0 1 1 1 1 Phosducin MRC1 PF09444.5 CBZ08697.1 - 0.0038 17.5 0.5 0.0067 16.7 0.3 1.4 1 0 0 1 1 1 1 MRC1-like domain Snurportin1 PF11538.3 CBZ08697.1 - 0.049 13.4 2.4 0.12 12.1 1.0 2.2 2 0 0 2 2 2 0 Snurportin1 Pertus-S5-tox PF09276.5 CBZ08697.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Pertussis toxin S5 subunit AAA PF00004.24 CBZ08698.1 - 7.4e-30 103.8 0.0 1.4e-26 93.2 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBZ08698.1 - 1e-09 38.5 0.0 0.0011 19.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CBZ08698.1 - 8.9e-08 32.3 15.2 0.00076 19.5 3.4 4.3 2 2 1 3 3 3 2 AAA ATPase domain NACHT PF05729.7 CBZ08698.1 - 1.6e-05 24.6 1.1 0.11 12.1 0.3 3.4 2 2 1 3 3 3 2 NACHT domain AAA_33 PF13671.1 CBZ08698.1 - 3.7e-05 23.6 0.0 0.043 13.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CBZ08698.1 - 4e-05 23.0 1.2 0.13 11.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_5 PF07728.9 CBZ08698.1 - 8e-05 22.3 0.2 0.011 15.4 0.0 2.9 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 CBZ08698.1 - 0.0001 22.5 0.4 0.22 11.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_17 PF13207.1 CBZ08698.1 - 0.00014 22.6 0.1 0.073 13.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CBZ08698.1 - 0.00022 21.3 0.0 0.17 12.1 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.1 CBZ08698.1 - 0.00034 20.0 0.2 0.39 10.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 CBZ08698.1 - 0.00083 18.5 0.5 0.82 8.7 0.1 2.3 2 0 0 2 2 2 2 Zeta toxin DUF258 PF03193.11 CBZ08698.1 - 0.0018 17.4 0.1 0.58 9.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 CBZ08698.1 - 0.0021 17.9 0.0 0.58 10.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 CBZ08698.1 - 0.003 18.0 0.0 0.42 11.1 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein AAA_30 PF13604.1 CBZ08698.1 - 0.0032 17.0 1.0 0.038 13.5 0.1 2.4 2 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CBZ08698.1 - 0.0036 17.0 0.0 0.42 10.2 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase NB-ARC PF00931.17 CBZ08698.1 - 0.0036 16.2 0.0 0.67 8.7 0.0 2.5 3 0 0 3 3 3 1 NB-ARC domain Viral_helicase1 PF01443.13 CBZ08698.1 - 0.0057 16.1 0.0 4.7 6.6 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 CBZ08698.1 - 0.0066 16.1 0.2 5.3 6.8 0.1 2.7 2 0 0 2 2 2 0 Part of AAA domain AAA_28 PF13521.1 CBZ08698.1 - 0.0086 16.0 0.1 3.3 7.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 CBZ08698.1 - 0.0097 15.3 1.1 0.05 13.0 0.0 2.1 2 0 0 2 2 2 1 FtsK/SpoIIIE family Sigma54_activat PF00158.21 CBZ08698.1 - 0.011 15.1 0.0 0.42 10.0 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF815 PF05673.8 CBZ08698.1 - 0.012 14.5 0.0 0.54 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TIP49 PF06068.8 CBZ08698.1 - 0.017 13.8 0.0 0.033 12.9 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus Rad17 PF03215.10 CBZ08698.1 - 0.018 13.7 0.2 1.5 7.4 0.1 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein UPF0079 PF02367.12 CBZ08698.1 - 0.029 13.9 0.3 6.6 6.3 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activ_2 PF14532.1 CBZ08698.1 - 0.041 13.9 0.8 5.1 7.1 0.1 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 CBZ08698.1 - 0.063 12.6 0.0 0.84 9.0 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 CBZ08698.1 - 0.07 12.2 0.1 1.2 8.2 0.0 2.5 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 CBZ08698.1 - 0.081 13.2 0.0 3.5 7.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 CBZ08698.1 - 0.13 11.9 0.1 3.2 7.4 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 CBZ08698.1 - 0.18 11.3 0.1 8.9 5.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 CBZ08698.1 - 0.19 12.0 0.2 20 5.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CBZ08698.1 - 0.5 9.7 1.9 19 4.5 0.3 2.3 2 0 0 2 2 2 0 AAA-like domain HEAT PF02985.17 CBZ08699.1 - 4.7e-11 41.7 16.4 0.063 13.3 0.1 7.9 7 0 0 7 7 7 4 HEAT repeat HEAT_2 PF13646.1 CBZ08699.1 - 1.2e-09 38.2 10.2 0.0007 19.8 0.0 4.4 4 0 0 4 4 4 3 HEAT repeats Adaptin_N PF01602.15 CBZ08699.1 - 0.00081 17.8 1.3 0.14 10.4 0.0 3.4 3 1 0 3 3 3 1 Adaptin N terminal region Erf4 PF10256.4 CBZ08699.1 - 0.1 12.4 0.0 0.3 10.9 0.0 1.8 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family Cnd1 PF12717.2 CBZ08699.1 - 0.11 12.3 0.7 45 3.8 0.0 3.3 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Xpo1 PF08389.7 CBZ08699.1 - 0.45 10.4 4.5 0.62 9.9 0.0 3.2 4 0 0 4 4 4 0 Exportin 1-like protein TFIIS_M PF07500.9 CBZ08700.1 - 5.6e-05 23.1 0.1 0.00012 22.1 0.0 1.6 1 1 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain IpaD PF06511.6 CBZ08700.1 - 0.25 10.3 1.8 0.29 10.0 1.3 1.1 1 0 0 1 1 1 0 Invasion plasmid antigen IpaD TFIIS_C PF01096.13 CBZ08700.1 - 0.28 10.8 5.4 0.3 10.7 0.5 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.2 CBZ08700.1 - 0.39 10.5 6.5 2 8.2 4.7 2.1 2 1 0 2 2 2 0 Transposase zinc-ribbon domain TFIIS_M PF07500.9 CBZ08701.1 - 2.6e-16 59.7 0.2 4.1e-16 59.0 0.1 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 CBZ08701.1 - 9.8e-15 53.9 4.5 1.8e-14 53.0 3.1 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Baculo_LEF5_C PF11792.3 CBZ08701.1 - 6.6e-05 22.2 0.6 0.00016 21.0 0.4 1.6 1 1 0 1 1 1 1 Baculoviridae late expression factor 5 C-terminal domain Elf1 PF05129.8 CBZ08701.1 - 0.1 12.3 1.4 0.19 11.4 1.0 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-DNL PF05180.7 CBZ08701.1 - 4.3 7.1 5.3 1.4 8.6 1.4 1.9 2 1 0 2 2 2 0 DNL zinc finger Zfx_Zfy_act PF04704.8 CBZ08702.1 - 0.032 13.0 0.0 0.046 12.5 0.0 1.2 1 0 0 1 1 1 0 Zfx / Zfy transcription activation region Pkinase PF00069.20 CBZ08703.1 - 1e-51 175.6 0.0 2.4e-51 174.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ08703.1 - 2e-24 86.0 0.0 2.4e-19 69.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase FHA PF00498.21 CBZ08703.1 - 2.6e-16 59.4 0.2 5.5e-16 58.4 0.2 1.6 1 0 0 1 1 1 1 FHA domain APH PF01636.18 CBZ08703.1 - 0.00032 20.5 0.2 0.89 9.2 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 CBZ08703.1 - 0.064 12.6 0.0 0.099 11.9 0.0 1.2 1 0 0 1 1 1 0 RIO1 family CAF1C_H4-bd PF12265.3 CBZ08704.1 - 4.1e-15 55.4 0.2 1.2e-14 53.9 0.1 1.8 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 CBZ08704.1 - 1.4e-10 40.6 10.8 0.00017 21.3 0.8 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat DEAD PF00270.24 CBZ08705.1 - 5.9e-33 113.7 1.2 1.4e-32 112.5 0.5 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ08705.1 - 6.8e-15 54.6 0.1 1.3e-08 34.5 0.1 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ08705.1 - 4.8e-05 23.2 0.1 0.0003 20.6 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CBZ08705.1 - 0.00057 18.7 0.0 0.0014 17.4 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain ATP-synt_D PF01813.12 CBZ08706.1 - 0.22 11.0 0.0 0.47 9.9 0.0 1.4 1 0 0 1 1 1 0 ATP synthase subunit D Metallophos PF00149.23 CBZ08707.1 - 8.7e-11 41.5 0.0 2.1e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase WD40 PF00400.27 CBZ08708.1 - 4.6e-13 48.4 5.9 1.9e-07 30.7 0.2 4.1 3 0 0 3 3 3 3 WD domain, G-beta repeat tify PF06200.9 CBZ08708.1 - 0.01 15.0 2.5 1.6 8.0 0.2 2.6 2 0 0 2 2 2 0 tify domain NIF PF03031.13 CBZ08709.1 - 6.6e-32 110.3 0.4 8.7e-32 109.9 0.3 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF705 PF05152.7 CBZ08709.1 - 0.078 11.9 0.2 0.12 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF705) zf-RING_2 PF13639.1 CBZ08710.1 - 0.00018 21.2 8.6 0.00077 19.2 6.0 2.2 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 CBZ08710.1 - 0.026 14.4 4.4 0.07 13.0 3.1 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4 PF00097.20 CBZ08710.1 - 0.11 12.1 7.2 0.26 10.9 5.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBZ08710.1 - 0.25 11.0 5.4 0.65 9.7 3.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 CBZ08710.1 - 0.69 10.0 6.4 1.6 8.8 4.5 1.7 1 0 0 1 1 1 0 RING-variant domain Fumerase PF05681.9 CBZ08712.1 - 2.9e-85 285.6 0.0 3.6e-85 285.3 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Fumerase_C PF05683.7 CBZ08712.1 - 2.5e-78 261.9 0.0 4.2e-78 261.2 0.0 1.4 1 0 0 1 1 1 1 Fumarase C-terminus Rsm22 PF09243.5 CBZ08713.1 - 3.2e-30 105.0 0.8 1.8e-17 63.3 0.1 3.1 3 0 0 3 3 3 2 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_18 PF12847.2 CBZ08713.1 - 0.011 16.3 0.3 3 8.4 0.0 2.9 2 1 1 3 3 3 0 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ08713.1 - 0.083 13.3 0.0 4.4 7.8 0.0 2.9 2 0 0 2 2 2 0 Methyltransferase domain Phosphodiest PF01663.17 CBZ08714.1 - 2.4e-09 36.9 1.1 3.6e-09 36.4 0.1 1.7 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 CBZ08714.1 - 0.021 14.2 0.1 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily Sulfatase PF00884.18 CBZ08714.1 - 0.031 13.4 0.1 0.054 12.6 0.0 1.3 1 0 0 1 1 1 0 Sulfatase Nuc_sug_transp PF04142.10 CBZ08716.1 - 1.9e-51 174.5 7.0 1.9e-51 174.5 4.8 1.5 2 0 0 2 2 2 1 Nucleotide-sugar transporter EmrE PF13536.1 CBZ08716.1 - 0.00051 20.2 20.8 0.00068 19.8 3.0 2.7 2 0 0 2 2 2 2 Multidrug resistance efflux transporter UAA PF08449.6 CBZ08716.1 - 0.016 14.1 10.6 0.028 13.3 7.3 1.4 1 0 0 1 1 1 0 UAA transporter family TPT PF03151.11 CBZ08716.1 - 3.8 7.1 21.8 8.8 5.9 1.1 3.6 3 1 0 3 3 3 0 Triose-phosphate Transporter family EamA PF00892.15 CBZ08716.1 - 5.5 7.0 27.4 0.078 13.0 2.2 3.4 2 1 1 3 3 3 0 EamA-like transporter family Aminotran_1_2 PF00155.16 CBZ08717.1 - 2.2e-69 234.1 0.0 2.5e-69 233.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II TPR_11 PF13414.1 CBZ08720.1 - 2.7e-07 30.1 1.1 1.3e-06 27.9 0.7 2.2 1 1 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 CBZ08720.1 - 0.021 14.7 0.1 5.4 7.1 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_C12 PF01088.16 CBZ08722.1 - 6.8e-60 201.8 0.0 9.4e-60 201.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 RPAP2_Rtr1 PF04181.8 CBZ08723.1 - 0.0036 17.3 0.0 0.0095 16.0 0.0 1.7 1 0 0 1 1 1 1 Rtr1/RPAP2 family WBP-1 PF11669.3 CBZ08724.1 - 0.0093 16.0 0.1 0.013 15.5 0.1 1.3 1 0 0 1 1 1 1 WW domain-binding protein 1 MAS20 PF02064.10 CBZ08724.1 - 0.015 15.2 0.0 0.019 14.8 0.0 1.1 1 0 0 1 1 1 0 MAS20 protein import receptor Protocadherin PF08374.6 CBZ08725.1 - 0.032 13.8 0.0 0.036 13.7 0.0 1.1 1 0 0 1 1 1 0 Protocadherin EphA2_TM PF14575.1 CBZ08725.1 - 0.11 12.8 0.1 0.14 12.5 0.0 1.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2852 PF11014.3 CBZ08725.1 - 0.13 12.2 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) HpcH_HpaI PF03328.9 CBZ08728.1 - 4.5e-19 68.2 0.1 1.1e-08 34.2 0.0 3.5 3 1 0 3 3 3 2 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 CBZ08728.1 - 1.4e-13 50.4 0.0 2.3e-07 29.9 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Clat_adaptor_s PF01217.15 CBZ08730.1 - 1.1e-44 151.6 0.9 1.3e-44 151.3 0.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PABP PF00658.13 CBZ08730.1 - 0.11 12.1 0.4 0.23 11.1 0.3 1.5 1 0 0 1 1 1 0 Poly-adenylate binding protein, unique domain LRR_6 PF13516.1 CBZ08732.1 - 0.0057 16.5 0.2 15 6.0 0.0 3.8 3 0 0 3 3 3 1 Leucine Rich repeat EF-hand_6 PF13405.1 CBZ08732.1 - 0.012 15.4 0.0 3.4 7.7 0.0 2.9 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.27 CBZ08732.1 - 0.048 12.9 0.7 16 5.1 0.0 3.1 3 0 0 3 3 3 0 EF hand RRM_1 PF00076.17 CBZ08733.1 - 1.3e-32 111.1 1.0 6.1e-22 77.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ08733.1 - 9.1e-25 86.4 0.4 6.9e-15 54.7 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ08733.1 - 6.5e-17 61.1 0.1 3e-10 39.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBZ08733.1 - 5.5e-05 22.8 0.0 0.018 14.7 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 CBZ08733.1 - 0.003 17.2 0.0 0.0069 16.1 0.0 1.6 1 0 0 1 1 1 1 Limkain b1 UBA PF00627.26 CBZ08734.1 - 5.9e-05 22.7 0.3 0.00013 21.6 0.2 1.6 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 CBZ08734.1 - 0.026 14.0 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain Rhomboid PF01694.17 CBZ08734.1 - 0.055 13.4 2.3 0.055 13.5 0.5 1.8 2 1 0 2 2 2 0 Rhomboid family PV-1 PF06637.6 CBZ08734.1 - 0.23 9.9 2.0 0.34 9.4 1.4 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) zf-rbx1 PF12678.2 CBZ08737.1 - 2.1e-22 79.0 8.7 2.8e-22 78.6 6.0 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CBZ08737.1 - 3.9e-12 45.8 9.4 5.4e-12 45.3 6.4 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 CBZ08737.1 - 4.5e-08 32.8 15.2 8.4e-07 28.7 10.4 2.1 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 CBZ08737.1 - 2.6e-06 26.9 10.9 4e-05 23.1 7.5 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ08737.1 - 9.6e-06 25.5 5.3 9.6e-06 25.5 3.7 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBZ08737.1 - 1.1e-05 25.0 3.5 1.1e-05 25.0 2.4 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H_2 PF13832.1 CBZ08737.1 - 0.0032 17.4 4.6 0.0043 17.0 3.2 1.3 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-RING_5 PF14634.1 CBZ08737.1 - 0.071 12.8 13.4 0.77 9.5 9.3 2.1 1 1 0 1 1 1 0 zinc-RING finger domain FANCL_C PF11793.3 CBZ08737.1 - 0.11 12.4 10.4 0.27 11.2 7.2 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain Baculo_RING PF05883.6 CBZ08737.1 - 0.37 10.6 5.5 1.3 8.8 3.8 1.8 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-HC5HC2H PF13771.1 CBZ08737.1 - 3.2 7.9 11.5 14 5.9 7.7 1.9 1 1 0 1 1 1 0 PHD-like zinc-binding domain RINGv PF12906.2 CBZ08737.1 - 6 7.0 13.1 0.47 10.5 4.5 2.3 2 1 0 2 2 2 0 RING-variant domain zf-RING_UBOX PF13445.1 CBZ08737.1 - 7.8 6.3 10.5 0.073 12.8 1.8 1.9 2 1 0 2 2 2 0 RING-type zinc-finger GST_C_2 PF13410.1 CBZ08738.1 - 7.8e-06 25.6 0.0 2.6e-05 24.0 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CBZ08738.1 - 3.5e-05 24.2 0.0 7.1e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CBZ08738.1 - 0.076 13.2 0.0 0.57 10.4 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain FAD_binding_2 PF00890.19 CBZ08739.1 - 2.6e-117 392.2 2.5 1.8e-116 389.4 0.8 2.0 2 0 0 2 2 2 1 FAD binding domain Succ_DH_flav_C PF02910.15 CBZ08739.1 - 2.5e-44 150.2 1.3 3.8e-44 149.6 0.9 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term DAO PF01266.19 CBZ08739.1 - 3.6e-05 22.8 0.2 0.02 13.7 0.1 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 CBZ08739.1 - 6.4e-05 22.1 0.1 0.033 13.2 0.1 2.7 3 0 0 3 3 3 2 Thi4 family Pyr_redox_2 PF07992.9 CBZ08739.1 - 0.00016 21.6 0.1 0.01 15.7 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CBZ08739.1 - 0.017 13.6 0.1 0.028 12.9 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 CBZ08739.1 - 0.041 12.7 3.3 0.092 11.5 1.7 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 CBZ08739.1 - 0.21 10.4 2.6 1 8.2 0.4 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_4 PF07993.7 CBZ08740.1 - 5.2e-65 218.8 0.0 7.4e-65 218.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 CBZ08740.1 - 3.8e-09 36.3 0.0 2.6e-08 33.6 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sterile PF03015.14 CBZ08740.1 - 2.2e-08 34.2 0.0 4.9e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 CBZ08740.1 - 0.00012 21.0 0.0 0.021 13.7 0.0 2.9 3 0 0 3 3 3 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 CBZ08740.1 - 0.0021 16.8 0.7 0.25 10.0 0.2 2.9 1 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 CBZ08740.1 - 0.011 16.0 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 CBZ08740.1 - 0.024 13.5 0.2 0.53 9.1 0.1 2.3 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein YjbE PF11106.3 CBZ08740.1 - 0.24 11.3 10.8 0.52 10.3 7.5 1.5 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE TMF_TATA_bd PF12325.3 CBZ08741.1 - 0.0052 16.5 12.4 0.0052 16.5 8.6 4.2 1 1 3 4 4 4 1 TATA element modulatory factor 1 TATA binding FlaC_arch PF05377.6 CBZ08741.1 - 0.016 15.0 9.4 1.2 9.1 0.1 4.4 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF2935 PF11155.3 CBZ08741.1 - 0.033 14.2 13.1 3.2 7.8 1.4 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF2935) DUF4515 PF14988.1 CBZ08741.1 - 0.034 13.8 47.5 0.085 12.5 18.9 3.0 1 1 1 3 3 3 0 Domain of unknown function (DUF4515) SpoU_methylase PF00588.14 CBZ08742.1 - 1.3e-14 54.2 0.0 8.6e-12 45.1 0.0 3.1 2 1 0 2 2 2 1 SpoU rRNA Methylase family BRF1 PF07741.8 CBZ08743.1 - 0.97 9.6 7.9 3.9 7.7 2.9 2.6 2 1 1 3 3 3 0 Brf1-like TBP-binding domain Ssl1 PF04056.9 CBZ08744.1 - 1.8e-18 66.8 0.1 3.6e-08 33.2 0.0 2.3 2 0 0 2 2 2 2 Ssl1-like VWA_2 PF13519.1 CBZ08744.1 - 0.002 18.2 0.2 0.0033 17.5 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain SET PF00856.23 CBZ08745.1 - 3.5e-09 37.1 0.0 3.6e-06 27.3 0.0 2.2 2 0 0 2 2 2 2 SET domain TPR_1 PF00515.23 CBZ08745.1 - 0.00043 19.7 0.4 0.00043 19.7 0.3 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ08745.1 - 0.011 15.6 2.5 0.015 15.1 0.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ08745.1 - 0.013 15.1 0.9 0.048 13.3 0.1 2.3 2 0 0 2 2 2 0 TPR repeat zf-FCS PF06467.9 CBZ08745.1 - 1.9 8.1 8.2 2.9 7.6 4.4 2.2 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif UQ_con PF00179.21 CBZ08747.1 - 1.4e-17 63.4 0.0 1.9e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBZ08747.1 - 0.0041 16.8 0.0 0.0071 16.0 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B WD40 PF00400.27 CBZ08748.1 - 4.7e-30 102.3 14.8 3.6e-08 32.9 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 CBZ08748.1 - 1e-06 28.5 0.1 0.14 11.8 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 CBZ08748.1 - 0.032 13.3 0.1 1.2 8.2 0.0 2.5 2 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.7 CBZ08748.1 - 0.074 10.8 1.1 0.88 7.2 0.0 2.5 2 1 0 2 2 2 0 IKI3 family Pkinase PF00069.20 CBZ08749.1 - 8.4e-51 172.6 0.0 1.3e-50 171.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ08749.1 - 3.1e-27 95.2 0.0 8e-27 93.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.1 CBZ08749.1 - 1.6e-06 27.7 0.4 0.00013 21.6 0.1 3.1 2 1 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.28 CBZ08749.1 - 2e-06 27.0 1.2 0.34 11.1 0.0 4.6 5 0 0 5 5 4 2 Leucine Rich Repeat LRR_4 PF12799.2 CBZ08749.1 - 7.8e-06 25.3 1.6 0.0046 16.5 0.2 3.8 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) Kinase-like PF14531.1 CBZ08749.1 - 1.3e-05 24.3 0.0 0.00012 21.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like C1_3 PF07649.7 CBZ08749.1 - 0.00033 20.6 9.7 0.00033 20.6 6.7 2.6 2 0 0 2 2 2 1 C1-like domain LRR_7 PF13504.1 CBZ08749.1 - 0.0066 16.4 3.2 1.8 9.0 0.0 4.2 3 0 0 3 3 3 1 Leucine rich repeat zf-B_box PF00643.19 CBZ08749.1 - 0.015 15.1 25.2 0.23 11.3 6.4 3.0 2 1 0 2 2 2 0 B-box zinc finger LRR_6 PF13516.1 CBZ08749.1 - 0.09 12.8 0.0 28 5.1 0.0 3.7 3 0 0 3 3 3 0 Leucine Rich repeat ZZ PF00569.12 CBZ08749.1 - 1.7 8.2 22.4 1.6 8.3 3.9 2.6 2 0 0 2 2 2 0 Zinc finger, ZZ type GCV_T PF01571.16 CBZ08750.1 - 6.8e-16 58.2 0.0 1e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 CBZ08750.1 - 3.1e-11 43.1 0.1 5e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain KAR9 PF08580.5 CBZ08750.1 - 0.14 10.4 0.8 0.19 9.9 0.5 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 SET PF00856.23 CBZ08751.1 - 6.4e-11 42.8 0.0 2.1e-10 41.1 0.0 2.0 2 1 0 2 2 2 1 SET domain RE_HindVP PF09519.5 CBZ08752.1 - 0.15 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 HindVP restriction endonuclease Inhibitor_I42 PF09394.5 CBZ08753.1 - 2.9e-23 81.9 0.0 3.5e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Chagasin family peptidase inhibitor I42 Inhibitor_I71 PF12628.2 CBZ08753.1 - 0.0039 16.8 0.2 0.98 9.0 0.0 2.1 1 1 1 2 2 2 2 Falstatin, cysteine peptidase inhibitor AMP-binding PF00501.23 CBZ08754.1 - 4e-22 78.1 0.7 1.4e-11 43.4 0.1 3.6 3 1 0 3 3 3 3 AMP-binding enzyme RRM_1 PF00076.17 CBZ08755.1 - 1.2e-16 60.0 0.0 3.6e-16 58.5 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ08755.1 - 2.8e-13 49.6 0.0 7.6e-13 48.2 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ08755.1 - 2.6e-07 30.3 0.1 4.1e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 CBZ08755.1 - 0.058 13.1 0.0 0.14 11.9 0.0 1.6 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif PAT1 PF09770.4 CBZ08755.1 - 1.1 7.3 36.5 1.3 7.1 25.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 adh_short PF00106.20 CBZ08757.1 - 1.7e-15 57.3 0.8 4.2e-15 56.0 0.2 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CBZ08757.1 - 2e-08 34.1 0.2 4.5e-08 32.9 0.2 1.6 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CBZ08757.1 - 0.0028 17.1 0.4 0.0084 15.5 0.1 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.1 CBZ08757.1 - 0.013 15.7 0.1 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_10 PF13460.1 CBZ08757.1 - 0.04 13.9 0.2 0.087 12.8 0.1 1.6 1 0 0 1 1 1 0 NADH(P)-binding dCMP_cyt_deam_1 PF00383.17 CBZ08757.1 - 0.067 12.8 0.3 0.47 10.1 0.2 2.2 2 0 0 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region adh_short PF00106.20 CBZ08758.1 - 7.9e-17 61.6 0.1 4.4e-16 59.2 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBZ08758.1 - 8.9e-08 31.9 0.0 8.9e-08 31.9 0.0 2.0 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 CBZ08758.1 - 0.0021 17.5 0.0 0.005 16.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 CBZ08758.1 - 0.0051 16.6 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase WVELL PF14043.1 CBZ08759.1 - 0.0032 17.0 0.4 0.0067 16.0 0.3 1.6 1 0 0 1 1 1 1 WVELL protein Amidase PF01425.16 CBZ08759.1 - 0.12 11.2 0.1 0.15 10.8 0.1 1.1 1 0 0 1 1 1 0 Amidase Abhydrolase_2 PF02230.11 CBZ08760.1 - 2.6e-38 131.6 0.0 3.4e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 CBZ08760.1 - 7.5e-11 41.9 0.1 1e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBZ08760.1 - 1.7e-06 28.1 1.0 0.0022 17.8 0.3 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family FSH1 PF03959.8 CBZ08760.1 - 0.019 14.4 0.0 0.04 13.3 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Esterase PF00756.15 CBZ08760.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase zf-DHHC PF01529.15 CBZ08762.1 - 8.1e-17 61.1 8.4 1.1e-16 60.7 2.8 2.4 2 1 0 2 2 2 2 DHHC palmitoyltransferase RRM_1 PF00076.17 CBZ08764.1 - 1.9e-21 75.4 0.0 2.6e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ08764.1 - 2.4e-15 56.2 0.0 4.1e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ08764.1 - 5.4e-13 48.5 0.0 8.6e-13 47.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YppG PF14179.1 CBZ08764.1 - 8.4 7.0 27.5 6.7 7.3 4.7 2.3 2 0 0 2 2 2 0 YppG-like protein eIF-5a PF01287.15 CBZ08765.1 - 2.2e-24 85.1 0.1 3.1e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.7 CBZ08765.1 - 0.0012 18.6 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain KOW PF00467.24 CBZ08765.1 - 0.054 13.2 0.4 0.054 13.2 0.3 1.8 2 0 0 2 2 2 0 KOW motif FlxA PF14282.1 CBZ08766.1 - 0.047 13.6 5.3 0.18 11.7 3.7 2.0 1 0 0 1 1 1 0 FlxA-like protein RNA_pol_N PF01194.12 CBZ08767.1 - 9e-29 99.2 0.8 1.1e-28 99.0 0.6 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Yippee-Mis18 PF03226.9 CBZ08767.1 - 0.094 12.7 0.6 0.12 12.3 0.4 1.3 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly CoA_binding PF02629.14 CBZ08768.1 - 1.4e-26 92.7 2.4 1.4e-26 92.7 1.7 2.1 3 0 0 3 3 3 1 CoA binding domain Ligase_CoA PF00549.14 CBZ08768.1 - 6.8e-23 80.9 0.7 1.1e-22 80.3 0.1 1.6 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.1 CBZ08768.1 - 7.6e-09 35.2 0.0 1.5e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 CBZ08768.1 - 0.00037 20.6 0.1 0.00078 19.5 0.1 1.6 1 0 0 1 1 1 1 CoA binding domain Arv1 PF04161.8 CBZ08770.1 - 1.3e-19 70.9 4.2 2.3e-19 70.1 2.9 1.5 1 1 0 1 1 1 1 Arv1-like family DUF2404 PF10296.4 CBZ08770.1 - 0.09 12.9 0.0 0.37 10.9 0.0 2.0 2 0 0 2 2 2 0 Putative integral membrane protein conserved region (DUF2404) FliL PF03748.9 CBZ08771.1 - 0.034 14.1 0.1 0.034 14.1 0.0 3.1 4 1 0 4 4 4 0 Flagellar basal body-associated protein FliL Peptidase_M24 PF00557.19 CBZ08773.1 - 1.4e-40 139.0 0.3 2.6e-40 138.2 0.1 1.5 2 0 0 2 2 2 1 Metallopeptidase family M24 PfkB PF00294.19 CBZ08774.1 - 1.7e-33 116.0 0.2 2.1e-33 115.7 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Histone PF00125.19 CBZ08775.1 - 3.7e-14 52.5 0.8 4.5e-14 52.3 0.6 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBZ08775.1 - 2.6e-05 24.1 0.1 4.3e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 CBZ08775.1 - 7.4e-05 22.6 0.1 0.00011 22.0 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.8 CBZ08775.1 - 0.00064 19.4 0.0 0.00081 19.0 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 CBZ08775.1 - 0.0013 18.5 0.0 0.0014 18.4 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit PCP_red PF08369.5 CBZ08775.1 - 0.033 14.0 1.0 0.064 13.1 0.3 1.9 2 1 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit FbpA PF05833.6 CBZ08775.1 - 0.049 12.1 0.0 0.057 11.9 0.0 1.0 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF4400 PF14348.1 CBZ08775.1 - 0.092 12.1 0.3 0.13 11.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) Galactosyl_T PF01762.16 CBZ08776.1 - 3.8e-05 23.3 0.2 0.00023 20.8 0.0 2.3 3 1 0 3 3 3 1 Galactosyltransferase Ribosomal_L30 PF00327.15 CBZ08780.1 - 9.6e-19 66.7 1.2 1.9e-18 65.7 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.7 CBZ08780.1 - 2.6e-16 59.3 14.7 5.2e-16 58.4 10.2 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Peptidase_M1 PF01433.15 CBZ08781.1 - 1.6e-114 383.0 0.0 2.9e-114 382.1 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 CBZ08781.1 - 3.8e-51 174.2 0.0 6.3e-51 173.5 0.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 CBZ08781.1 - 3.3e-18 65.9 1.2 7.6e-18 64.7 0.4 2.0 2 0 0 2 2 2 1 Peptidase MA superfamily DUF45 PF01863.12 CBZ08781.1 - 0.052 13.3 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF45 Ribosomal_S9 PF00380.14 CBZ08785.1 - 1.9e-29 102.3 0.9 2.2e-29 102.1 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 NuA4 PF09340.5 CBZ08790.1 - 1.3e-07 31.1 0.0 2.7e-06 26.9 0.0 2.3 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Pkinase PF00069.20 CBZ08791.1 - 5.6e-05 22.4 0.0 9.6e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain CDP-OH_P_transf PF01066.16 CBZ08794.1 - 5.5e-15 55.4 17.9 2.6e-14 53.3 12.4 2.1 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase IBV_3A PF03617.8 CBZ08794.1 - 0.039 13.6 0.3 0.12 12.1 0.2 1.8 1 0 0 1 1 1 0 IBV 3A protein Glucosamine_iso PF01182.15 CBZ08796.1 - 2.2e-45 154.8 0.1 2.6e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase APG9 PF04109.11 CBZ08797.1 - 1.1e-43 149.5 0.0 5e-43 147.4 0.0 1.8 1 1 0 1 1 1 1 Autophagy protein Apg9 DUF3525 PF12039.3 CBZ08797.1 - 0.031 12.7 0.3 0.05 12.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) Peptidase_C2 PF00648.16 CBZ08798.1 - 3.6e-71 239.5 0.0 1.9e-27 96.0 0.0 3.3 3 0 0 3 3 3 3 Calpain family cysteine protease Calpain_III PF01067.17 CBZ08798.1 - 1.2e-24 86.6 0.0 1.1e-08 34.7 0.0 4.1 4 0 0 4 4 4 3 Calpain large subunit, domain III phage_tail_N PF08400.5 CBZ08798.1 - 0.12 12.0 0.3 1.8e+02 1.8 0.0 4.2 4 0 0 4 4 4 0 Prophage tail fibre N-terminal Radial_spoke_3 PF06098.6 CBZ08799.1 - 3.8e-119 397.0 29.0 4.4e-119 396.8 20.1 1.0 1 0 0 1 1 1 1 Radial spoke protein 3 eIF3_p135 PF12807.2 CBZ08799.1 - 0.2 11.6 6.2 0.041 13.8 1.8 1.6 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit 135 Vfa1 PF08432.5 CBZ08799.1 - 6.4 6.7 14.9 2.6 8.0 4.6 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Amastin PF07344.6 CBZ08801.1 - 2.7e-10 40.0 6.9 2.7e-10 40.0 4.8 1.7 2 0 0 2 2 2 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ08801.1 - 0.22 11.1 18.0 0.023 14.3 7.2 2.0 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Rep_fac_C PF08542.6 CBZ08802.1 - 2.4e-16 59.5 0.0 1.8e-15 56.6 0.0 2.2 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 CBZ08802.1 - 4.3e-12 45.9 0.0 4.8e-11 42.5 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 CBZ08802.1 - 3.5e-11 43.4 0.1 1.6e-10 41.2 0.0 2.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CBZ08802.1 - 1.8e-09 36.8 0.0 6.2e-07 28.4 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 CBZ08802.1 - 6.1e-08 32.8 0.0 1.7e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CBZ08802.1 - 2.5e-05 23.5 0.0 0.00097 18.3 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 CBZ08802.1 - 4.6e-05 23.4 0.6 0.00098 19.1 0.4 2.5 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 CBZ08802.1 - 4.7e-05 22.5 0.0 0.00012 21.2 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CBZ08802.1 - 6.4e-05 22.6 0.0 0.00019 21.1 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain DNA_pol3_delta PF06144.8 CBZ08802.1 - 0.00013 21.5 0.1 0.00034 20.1 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_30 PF13604.1 CBZ08802.1 - 0.00058 19.4 0.1 0.0021 17.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 CBZ08802.1 - 0.00091 18.7 0.0 0.0023 17.4 0.0 1.9 1 1 0 1 1 1 1 AAA-like domain AAA_25 PF13481.1 CBZ08802.1 - 0.001 18.5 0.1 0.0043 16.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 CBZ08802.1 - 0.0022 17.5 0.0 0.0042 16.5 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_14 PF13173.1 CBZ08802.1 - 0.0027 17.6 0.0 0.008 16.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 CBZ08802.1 - 0.0084 15.1 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.9 CBZ08802.1 - 0.011 15.4 0.1 0.25 11.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 CBZ08802.1 - 0.02 15.0 0.0 0.061 13.4 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.1 CBZ08802.1 - 0.031 14.1 0.6 0.073 12.9 0.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.1 CBZ08802.1 - 0.036 13.6 0.0 0.046 13.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 CBZ08802.1 - 0.039 13.3 0.0 0.083 12.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.8 CBZ08802.1 - 0.041 12.6 0.2 0.84 8.2 0.0 2.2 2 0 0 2 2 2 0 TIP49 C-terminus AAA_24 PF13479.1 CBZ08802.1 - 0.044 13.3 0.3 0.11 12.0 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 CBZ08802.1 - 0.071 13.4 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 CBZ08802.1 - 0.097 12.2 0.1 19 4.8 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.20 CBZ08803.1 - 3.7e-64 216.3 0.0 4.2e-64 216.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ08803.1 - 1.4e-27 96.3 0.0 2e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ08803.1 - 0.069 12.8 0.1 0.15 11.7 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CBZ08803.1 - 0.081 11.6 0.0 0.33 9.6 0.0 1.9 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase zf-RING_2 PF13639.1 CBZ08804.1 - 2.9e-10 39.8 6.9 2.9e-10 39.8 4.8 2.5 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.20 CBZ08804.1 - 3.5e-07 29.7 7.5 3.5e-07 29.7 5.2 2.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 CBZ08804.1 - 4.9e-07 29.3 4.1 4.9e-07 29.3 2.8 2.6 2 1 0 2 2 1 1 PHD-finger zf-RING_5 PF14634.1 CBZ08804.1 - 9.6e-07 28.4 6.9 9.6e-07 28.4 4.8 2.8 2 1 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBZ08804.1 - 5.8e-06 25.8 5.2 5.8e-06 25.8 3.6 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBZ08804.1 - 7.8e-06 25.9 2.9 7.8e-06 25.9 2.0 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CBZ08804.1 - 0.00014 21.7 8.4 0.00014 21.7 5.8 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBZ08804.1 - 0.0036 16.9 4.1 0.0036 16.9 2.8 2.0 2 0 0 2 2 2 1 RING-type zinc-finger Rtf2 PF04641.7 CBZ08804.1 - 0.0049 16.1 3.5 0.009 15.2 0.7 2.3 2 0 0 2 2 2 1 Rtf2 RING-finger zf-C3HC4_4 PF15227.1 CBZ08804.1 - 0.012 15.4 3.4 0.012 15.4 2.4 2.4 3 0 0 3 3 2 0 zinc finger of C3HC4-type, RING CbiM PF01891.11 CBZ08804.1 - 0.033 13.8 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 Cobalt uptake substrate-specific transmembrane region zf-Apc11 PF12861.2 CBZ08804.1 - 0.058 13.2 6.6 0.036 13.9 1.2 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 CBZ08804.1 - 0.36 10.4 20.8 0.022 14.3 5.1 2.9 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.1 CBZ08804.1 - 1.1 9.1 9.1 0.078 12.7 1.4 2.5 2 0 0 2 2 2 0 Zinc-binding RING-finger Prok-RING_4 PF14447.1 CBZ08804.1 - 2.2 7.8 9.3 0.18 11.3 2.6 2.1 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 WD40 PF00400.27 CBZ08805.1 - 1.7e-09 37.1 3.9 0.002 17.9 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat LisH PF08513.6 CBZ08805.1 - 0.0011 18.6 0.1 0.0021 17.7 0.0 1.5 1 0 0 1 1 1 1 LisH DUF4471 PF14740.1 CBZ08806.1 - 6.5e-86 288.1 0.0 9.6e-86 287.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) DUF4470 PF14737.1 CBZ08806.1 - 1e-20 73.2 0.0 2.6e-20 72.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) MRP-S28 PF10213.4 CBZ08810.1 - 0.00016 21.7 0.1 0.0004 20.4 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Snapin_Pallidin PF14712.1 CBZ08811.1 - 0.06 13.6 0.1 0.17 12.2 0.1 1.7 1 0 0 1 1 1 0 Snapin/Pallidin DUF2186 PF09952.4 CBZ08812.1 - 0.22 11.7 1.4 0.29 11.3 1.0 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2186) Mucin PF01456.12 CBZ08813.1 - 2e-06 27.6 47.4 2e-06 27.6 32.8 1.8 2 0 0 2 2 2 1 Mucin-like glycoprotein MGC-24 PF05283.6 CBZ08813.1 - 0.0013 18.6 21.0 0.0038 17.0 14.5 1.8 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24) Rifin_STEVOR PF02009.11 CBZ08813.1 - 0.03 13.9 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 Rifin/stevor family AJAP1_PANP_C PF15298.1 CBZ08813.1 - 0.14 11.9 27.0 0.31 10.8 18.7 1.5 1 0 0 1 1 1 0 AJAP1/PANP C-terminus ABC2_membrane_3 PF12698.2 CBZ08813.1 - 0.71 8.8 6.9 1.8 7.5 4.8 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein Aa_trans PF01490.13 CBZ08814.1 - 1.4e-53 181.8 33.1 1.8e-53 181.5 23.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.13 CBZ08815.1 - 5e-26 91.1 13.5 5.7e-26 90.9 9.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3082 PF11282.3 CBZ08815.1 - 2.5 8.2 11.8 1.6 8.8 2.4 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3082) DUF3169 PF11368.3 CBZ08815.1 - 3.9 6.6 6.4 2.8 7.0 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Aa_trans PF01490.13 CBZ08816.1 - 7e-46 156.5 38.2 8.8e-46 156.1 26.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CBZ08816.1 - 4.2e-10 39.0 20.9 4.2e-10 39.0 14.5 1.5 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family DUF843 PF05814.6 CBZ08816.1 - 1.2 8.9 6.9 0.25 11.1 0.6 2.4 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) LRR_4 PF12799.2 CBZ08817.1 - 0.0057 16.2 0.0 0.066 12.8 0.0 2.0 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ08817.1 - 0.33 10.7 2.5 1.9 8.3 0.0 2.6 3 0 0 3 3 3 0 Leucine rich repeat UBA PF00627.26 CBZ08820.1 - 2.9e-10 39.6 0.3 8e-10 38.2 0.2 1.8 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 CBZ08820.1 - 0.028 13.9 0.1 0.063 12.8 0.1 1.6 1 0 0 1 1 1 0 UBA-like domain NAD_binding_1 PF00175.16 CBZ08821.1 - 8.4e-17 61.7 0.0 1.4e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CBZ08821.1 - 2.9e-14 52.9 0.0 4.5e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 CBZ08821.1 - 0.0002 21.2 0.0 0.00079 19.3 0.0 1.8 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Oxidored_q6 PF01058.17 CBZ08822.1 - 2.5e-19 69.2 0.1 3.2e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Dabb PF07876.7 CBZ08823.1 - 2.6e-10 40.5 0.0 3.5e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Dabb PF07876.7 CBZ08824.1 - 1.2e-08 35.2 0.0 1.6e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Ras PF00071.17 CBZ08825.1 - 3.8e-64 214.9 0.6 4.4e-64 214.7 0.4 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ08825.1 - 9.1e-22 77.7 0.1 1.3e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBZ08825.1 - 2.8e-16 59.2 0.1 3.4e-16 58.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBZ08825.1 - 4.6e-08 32.4 0.1 5.6e-08 32.2 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBZ08825.1 - 6.2e-06 25.7 0.2 1.2e-05 24.8 0.2 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CBZ08825.1 - 2.5e-05 23.5 0.1 3.6e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CBZ08825.1 - 0.00023 21.0 0.1 0.00038 20.4 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBZ08825.1 - 0.00032 20.0 0.1 0.0016 17.7 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.1 CBZ08825.1 - 0.002 18.2 0.0 0.0042 17.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 CBZ08825.1 - 0.0064 16.6 0.0 0.58 10.3 0.0 2.3 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 CBZ08825.1 - 0.007 15.5 0.0 0.019 14.1 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 CBZ08825.1 - 0.013 15.7 0.2 0.082 13.2 0.1 1.9 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 CBZ08825.1 - 0.018 15.0 0.0 0.033 14.1 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain G-alpha PF00503.15 CBZ08825.1 - 0.036 12.7 4.8 0.23 10.1 0.6 2.6 1 1 1 2 2 2 0 G-protein alpha subunit AAA_29 PF13555.1 CBZ08825.1 - 0.046 13.2 0.0 0.098 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 CBZ08825.1 - 0.11 12.2 0.1 0.23 11.1 0.0 1.8 1 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Pkinase PF00069.20 CBZ08826.1 - 0.016 14.3 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain DUF607 PF04678.8 CBZ08827.1 - 6.7e-54 182.5 0.2 1.2e-53 181.7 0.1 1.4 2 0 0 2 2 2 1 Protein of unknown function, DUF607 Glyoxalase_4 PF13669.1 CBZ08827.1 - 0.0072 16.3 0.1 0.019 14.9 0.0 1.7 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily GerA PF03323.8 CBZ08827.1 - 0.1 10.6 0.0 0.15 10.1 0.0 1.1 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein MatE PF01554.13 CBZ08828.1 - 7.8e-37 126.3 21.0 4.9e-22 78.2 5.7 2.4 2 0 0 2 2 2 2 MatE FAM176 PF14851.1 CBZ08828.1 - 0.079 12.6 0.1 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 FAM176 family LRR_6 PF13516.1 CBZ08829.1 - 1.4e-05 24.6 3.5 0.26 11.4 0.0 4.0 4 0 0 4 4 4 2 Leucine Rich repeat LRR_8 PF13855.1 CBZ08829.1 - 0.018 14.7 1.2 0.41 10.4 0.5 2.8 2 0 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.2 CBZ08829.1 - 0.023 14.3 4.5 2.6 7.7 0.4 3.2 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBZ08829.1 - 0.11 12.5 5.0 81 3.8 0.1 4.8 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_7 PF13504.1 CBZ08829.1 - 0.45 10.9 3.0 1.1e+02 3.6 0.0 4.3 3 0 0 3 3 3 0 Leucine rich repeat Glutaredoxin PF00462.19 CBZ08830.1 - 9.3e-17 60.7 0.1 1.3e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.1 CBZ08830.1 - 2.4e-05 24.0 0.1 3.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.1 CBZ08830.1 - 0.00027 21.1 0.2 0.0013 18.9 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain GST_N_3 PF13417.1 CBZ08830.1 - 0.0004 20.5 0.0 0.00054 20.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DSBA PF01323.15 CBZ08830.1 - 0.0023 17.5 0.4 0.14 11.7 0.2 2.1 1 1 1 2 2 2 1 DSBA-like thioredoxin domain DUF836 PF05768.9 CBZ08830.1 - 0.0028 17.8 0.1 0.0036 17.5 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_4 PF13462.1 CBZ08830.1 - 0.0065 16.5 0.4 3 7.8 0.2 2.1 1 1 1 2 2 2 2 Thioredoxin Redoxin PF08534.5 CBZ08830.1 - 0.11 12.0 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 Redoxin Beta_helix PF13229.1 CBZ08831.1 - 4.4e-91 302.7 106.5 9e-16 58.0 6.3 16.4 9 5 4 14 14 14 13 Right handed beta helix region NosD PF05048.8 CBZ08831.1 - 2.6e-73 246.0 37.2 1.2e-11 44.2 6.0 15.0 9 4 6 15 15 15 12 Periplasmic copper-binding protein (NosD) End3 PF12761.2 CBZ08831.1 - 0.41 10.2 0.1 0.77 9.3 0.0 1.3 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DMAP1 PF05499.7 CBZ08831.1 - 0.43 10.1 0.0 0.91 9.0 0.0 1.4 1 0 0 1 1 1 0 DNA methyltransferase 1-associated protein 1 (DMAP1) CorA PF01544.13 CBZ08831.1 - 2.8 6.9 0.1 5.8 5.8 0.1 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF1126 PF06565.7 CBZ08833.1 - 5e-44 147.4 0.1 8.2e-14 50.7 0.0 3.7 3 0 0 3 3 3 3 Repeat of unknown function (DUF1126) EF-hand_7 PF13499.1 CBZ08833.1 - 1.2e-11 44.5 0.2 2.5e-10 40.3 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 CBZ08833.1 - 3.2e-08 33.0 2.6 0.00056 19.4 0.1 3.8 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 CBZ08833.1 - 1.8e-07 29.9 1.4 0.021 14.1 0.0 4.9 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.1 CBZ08833.1 - 3.7e-05 23.2 0.2 0.16 11.9 0.1 4.3 4 0 0 4 4 4 1 EF-hand domain PIP5K PF01504.13 CBZ08835.1 - 7.7e-63 211.9 0.0 1.3e-62 211.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase FYVE PF01363.16 CBZ08835.1 - 2.2e-16 59.5 4.3 4.4e-16 58.5 3.0 1.5 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.16 CBZ08835.1 - 0.0098 15.7 3.2 0.026 14.3 2.2 1.7 1 0 0 1 1 1 1 IBR domain COX_ARM PF06481.9 CBZ08835.1 - 0.013 15.1 0.3 0.11 12.2 0.0 2.6 3 0 0 3 3 3 0 COX Aromatic Rich Motif C1_4 PF07975.7 CBZ08835.1 - 1.2 9.1 7.5 2.8 8.0 5.2 1.6 1 0 0 1 1 1 0 TFIIH C1-like domain HypA PF01155.14 CBZ08835.1 - 4.8 6.9 7.1 0.44 10.2 1.2 2.0 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 CBZ08835.1 - 8.4 6.4 9.0 25 4.9 6.2 1.9 1 0 0 1 1 1 0 Zinc ribbon domain zf-rbx1 PF12678.2 CBZ08838.1 - 2.5e-08 33.9 9.4 5.5e-08 32.8 6.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CBZ08838.1 - 4.1e-08 32.9 14.5 1.1e-07 31.5 10.0 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBZ08838.1 - 9.7e-06 25.5 11.2 2.3e-05 24.3 7.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CBZ08838.1 - 3e-05 23.7 4.7 6.1e-05 22.7 3.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 CBZ08838.1 - 0.00057 19.4 11.2 0.0013 18.3 7.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ08838.1 - 0.024 14.3 12.9 0.056 13.1 8.9 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBZ08838.1 - 0.61 9.8 15.1 0.24 11.0 7.9 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Dpy-30 PF05186.8 CBZ08843.1 - 4.1e-06 26.1 0.1 7.7e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Dpy-30 motif AAA_17 PF13207.1 CBZ08843.1 - 0.0078 17.0 2.6 0.13 13.0 0.0 3.5 3 0 0 3 3 3 1 AAA domain DUF1682 PF07946.9 CBZ08843.1 - 4.6 5.9 7.0 9.2 5.0 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF420 PF04238.7 CBZ08845.1 - 0.049 13.5 6.4 1.9 8.4 3.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF420) GWT1 PF06423.7 CBZ08845.1 - 0.24 11.5 2.8 0.35 10.9 2.0 1.4 1 0 0 1 1 1 0 GWT1 SUR7 PF06687.7 CBZ08846.1 - 0.013 15.0 0.1 0.02 14.4 0.1 1.3 1 0 0 1 1 1 0 SUR7/PalI family Peptidase_M8 PF01457.11 CBZ08848.1 - 1.1e-143 479.3 0.1 1.3e-143 479.0 0.1 1.0 1 0 0 1 1 1 1 Leishmanolysin SprT-like PF10263.4 CBZ08848.1 - 0.14 11.7 0.0 0.36 10.4 0.0 1.7 1 0 0 1 1 1 0 SprT-like family Peptidase_M8 PF01457.11 CBZ08849.1 - 1.1e-143 479.3 0.1 1.3e-143 479.0 0.1 1.0 1 0 0 1 1 1 1 Leishmanolysin SprT-like PF10263.4 CBZ08849.1 - 0.14 11.7 0.0 0.36 10.4 0.0 1.7 1 0 0 1 1 1 0 SprT-like family rve PF00665.21 CBZ08850.1 - 0.076 13.1 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain Ribosomal_S10 PF00338.17 CBZ08852.1 - 3.4e-25 87.7 0.3 3.9e-25 87.5 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Endomucin PF07010.7 CBZ08852.1 - 0.035 13.4 2.7 0.033 13.5 1.4 1.2 1 1 0 1 1 1 0 Endomucin Ribosomal_S10 PF00338.17 CBZ08853.1 - 3.4e-25 87.7 0.3 3.9e-25 87.5 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Endomucin PF07010.7 CBZ08853.1 - 0.035 13.4 2.7 0.033 13.5 1.4 1.2 1 1 0 1 1 1 0 Endomucin zf-CCCH PF00642.19 CBZ08854.1 - 0.00026 20.6 4.6 0.00046 19.8 3.2 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SNARE PF05739.14 CBZ08855.1 - 6.1e-16 57.8 1.0 6.1e-16 57.8 0.7 2.1 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 CBZ08855.1 - 0.0014 18.7 12.6 0.0025 17.9 2.3 2.5 2 1 0 2 2 2 2 Syntaxin bact-PGI_C PF10432.4 CBZ08855.1 - 0.019 14.6 0.7 0.03 14.0 0.5 1.4 1 0 0 1 1 1 0 Bacterial phospho-glucose isomerase C-terminal region DUF2400 PF09674.5 CBZ08855.1 - 0.023 14.3 0.3 0.023 14.3 0.2 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2400) zf-HIT PF04438.11 CBZ08856.1 - 2.3 7.9 7.6 4.8 6.9 5.3 1.5 1 0 0 1 1 1 0 HIT zinc finger AAA PF00004.24 CBZ08857.1 - 1.5e-32 112.5 0.0 2.3e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBZ08857.1 - 3.9e-07 30.2 0.0 7.8e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBZ08857.1 - 8.7e-07 29.3 0.0 1.5e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBZ08857.1 - 2.3e-06 27.5 0.0 5.7e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBZ08857.1 - 3e-06 28.0 0.0 5.9e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBZ08857.1 - 1.5e-05 25.1 0.0 3.9e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 CBZ08857.1 - 0.00028 20.6 0.0 0.0012 18.5 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 CBZ08857.1 - 0.00055 19.3 0.0 0.0017 17.8 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein RNA_helicase PF00910.17 CBZ08857.1 - 0.00098 19.2 0.0 0.0038 17.3 0.0 1.9 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.1 CBZ08857.1 - 0.0016 18.4 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBZ08857.1 - 0.002 17.8 0.1 0.015 14.9 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain RuvB_N PF05496.7 CBZ08857.1 - 0.0023 16.9 0.0 0.0051 15.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 CBZ08857.1 - 0.0031 16.9 0.5 0.093 12.1 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.1 CBZ08857.1 - 0.0064 16.1 0.0 0.011 15.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain UPF0079 PF02367.12 CBZ08857.1 - 0.0098 15.5 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 CBZ08857.1 - 0.01 15.4 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 CBZ08857.1 - 0.015 14.5 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MobB PF03205.9 CBZ08857.1 - 0.035 13.7 0.0 0.069 12.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 CBZ08857.1 - 0.041 13.5 0.0 0.08 12.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.1 CBZ08857.1 - 0.071 12.6 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 CBZ08857.1 - 0.11 11.2 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus AAA_14 PF13173.1 CBZ08857.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 CBZ08857.1 - 0.16 11.8 0.0 0.72 9.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_23 PF13476.1 CBZ08857.1 - 0.28 11.4 0.0 0.44 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain Zip PF02535.17 CBZ08858.1 - 6.8e-37 127.1 13.2 6.8e-37 127.1 9.1 2.4 2 1 0 2 2 2 1 ZIP Zinc transporter zf-Tim10_DDP PF02953.10 CBZ08859.1 - 0.027 13.7 0.7 0.039 13.2 0.5 1.2 1 0 0 1 1 1 0 Tim10/DDP family zinc finger DUF2306 PF10067.4 CBZ08859.1 - 0.056 13.5 1.2 0.067 13.3 0.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2306) HSP70 PF00012.15 CBZ08860.1 - 2.5e-256 851.3 3.5 2.9e-256 851.1 2.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBZ08860.1 - 2e-14 52.9 0.1 2.8e-13 49.1 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein Asp_decarbox PF02261.11 CBZ08860.1 - 0.0012 18.4 0.0 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 Aspartate decarboxylase FtsA PF14450.1 CBZ08860.1 - 0.016 15.0 1.0 0.73 9.6 0.7 3.2 1 1 0 1 1 1 0 Cell division protein FtsA FGGY_C PF02782.11 CBZ08860.1 - 0.024 14.2 0.0 0.049 13.2 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 CBZ08860.1 - 0.05 12.7 0.4 4 6.4 0.1 2.4 1 1 1 2 2 2 0 Hydantoinase/oxoprolinase HSP70 PF00012.15 CBZ08861.1 - 3.7e-272 903.6 5.2 4.2e-272 903.4 3.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBZ08861.1 - 3.4e-14 52.1 0.1 4.1e-13 48.6 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein Asp_decarbox PF02261.11 CBZ08861.1 - 0.0015 18.1 0.0 0.0029 17.1 0.0 1.4 1 0 0 1 1 1 1 Aspartate decarboxylase FtsA PF14450.1 CBZ08861.1 - 0.027 14.3 0.9 0.94 9.3 0.6 3.1 1 1 0 1 1 1 0 Cell division protein FtsA Nucleoporin_FG PF13634.1 CBZ08863.1 - 6.7e-05 23.0 115.9 17 5.6 9.2 5.6 1 1 2 3 3 3 1 Nucleoporin FG repeat region zf-Sec23_Sec24 PF04810.10 CBZ08863.1 - 0.12 11.9 0.7 16 5.1 0.2 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Cytochrome_C7 PF14522.1 CBZ08863.1 - 0.26 10.9 5.2 5.9 6.6 0.2 2.4 2 0 0 2 2 2 0 Cytochrome c7 Cytochrome_CBB3 PF13442.1 CBZ08863.1 - 0.96 9.6 8.1 4.9 7.3 0.1 3.6 3 0 0 3 3 3 0 Cytochrome C oxidase, cbb3-type, subunit III Ribosomal_L4 PF00573.17 CBZ08867.1 - 1.2e-39 135.7 0.1 1.9e-39 135.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 CBZ08867.1 - 2.8e-15 55.9 3.9 2.8e-15 55.9 2.7 2.3 2 1 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Ribosomal_L4 PF00573.17 CBZ08868.1 - 1.1e-39 135.8 0.1 1.8e-39 135.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 CBZ08868.1 - 1.7e-15 56.6 6.6 2.8e-15 55.9 2.7 2.4 2 1 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Pkinase PF00069.20 CBZ08870.1 - 2.4e-60 203.8 0.0 1e-59 201.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ08870.1 - 4.7e-33 114.3 0.0 1.3e-23 83.4 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.9 CBZ08870.1 - 0.0011 18.0 0.0 0.0021 17.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBZ08870.1 - 0.19 10.6 0.0 5.3 5.8 0.0 2.4 2 1 0 2 2 2 0 Kinase-like Amastin PF07344.6 CBZ08872.1 - 1.1e-50 171.2 15.6 1.3e-50 171.0 10.8 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ08872.1 - 5.3 6.6 21.0 0.15 11.7 9.4 2.0 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction MFS_1 PF07690.11 CBZ08873.1 - 1.6e-21 76.4 22.8 1.4e-13 50.3 13.7 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 CBZ08873.1 - 4e-13 49.1 17.9 4e-13 49.1 12.4 2.7 2 1 0 2 2 2 1 Nodulin-like Nodulin-like PF06813.8 CBZ08874.1 - 3.4e-10 39.5 11.7 3.4e-10 39.5 8.1 2.8 2 1 0 2 2 2 1 Nodulin-like Flagellar_rod PF05149.7 CBZ08875.1 - 7.4e-106 353.5 28.6 7.4e-106 353.5 19.8 2.8 2 1 1 3 3 3 2 Paraflagellar rod protein DUF1120 PF06551.7 CBZ08875.1 - 0.13 12.5 1.1 0.36 11.1 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1120) Gpi1 PF05024.10 CBZ08877.1 - 9.8e-32 110.1 6.0 4e-21 75.5 3.6 2.5 1 1 1 2 2 2 2 N-acetylglucosaminyl transferase component (Gpi1) Nol1_Nop2_Fmu PF01189.12 CBZ08879.1 - 8e-31 107.4 0.0 8.1e-28 97.5 0.0 2.1 2 0 0 2 2 2 2 NOL1/NOP2/sun family FtsJ PF01728.14 CBZ08879.1 - 3.6e-05 23.8 0.0 8.9e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 CBZ08879.1 - 0.001 19.1 0.1 0.0039 17.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain LRR_4 PF12799.2 CBZ08880.1 - 6.3e-24 83.1 0.0 0.021 14.4 0.0 10.1 8 2 2 11 11 11 7 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 CBZ08880.1 - 2.1e-05 23.9 10.9 4.1 8.0 0.0 9.8 9 0 0 9 9 9 1 Leucine rich repeat LRR_1 PF00560.28 CBZ08880.1 - 2.5e-05 23.7 9.3 26 5.3 0.0 10.5 11 2 0 11 11 11 1 Leucine Rich Repeat LRR_8 PF13855.1 CBZ08880.1 - 6.5e-05 22.5 12.4 2.2 8.0 0.0 7.7 5 3 4 9 9 9 2 Leucine rich repeat DUF1081 PF06448.6 CBZ08880.1 - 0.075 12.9 0.1 1.6 8.6 0.0 3.0 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1081) PLAC8 PF04749.12 CBZ08884.1 - 1.5e-15 57.6 25.4 1.9e-15 57.2 17.6 1.1 1 0 0 1 1 1 1 PLAC8 family PLAC8 PF04749.12 CBZ08885.1 - 4.2e-15 56.2 23.3 5.3e-15 55.8 16.1 1.1 1 0 0 1 1 1 1 PLAC8 family PLAC8 PF04749.12 CBZ08886.1 - 1.6e-15 57.5 25.9 2e-15 57.2 17.9 1.1 1 0 0 1 1 1 1 PLAC8 family DUF4339 PF14237.1 CBZ08888.1 - 2.1e-16 59.2 0.3 5e-16 57.9 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4339) DnaJ PF00226.26 CBZ08888.1 - 4.5e-16 58.3 0.4 1e-15 57.2 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain CDC14 PF08045.6 CBZ08888.1 - 0.036 13.2 2.5 0.045 12.8 0.5 2.0 2 0 0 2 2 2 0 Cell division control protein 14, SIN component zf-MIZ PF02891.15 CBZ08890.1 - 5.3e-18 64.2 5.2 9.5e-18 63.4 3.6 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 CBZ08890.1 - 0.00016 21.1 1.4 0.00033 20.1 1.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit PWWP PF00855.12 CBZ08890.1 - 0.0011 19.0 0.1 0.0025 17.9 0.1 1.7 1 0 0 1 1 1 1 PWWP domain S-AdoMet_synt_C PF02773.11 CBZ08891.1 - 3e-70 234.3 0.2 4.9e-70 233.6 0.1 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 CBZ08891.1 - 5.3e-46 155.4 0.0 9.7e-45 151.3 0.0 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 CBZ08891.1 - 4.3e-40 135.9 0.2 8.6e-40 135.0 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Strep_pep PF14404.1 CBZ08891.1 - 0.032 14.4 0.0 0.081 13.1 0.0 1.6 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Streptomyces species zf-MIZ PF02891.15 CBZ08892.1 - 5.3e-18 64.2 5.2 9.5e-18 63.4 3.6 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 CBZ08892.1 - 0.00016 21.1 1.4 0.00033 20.1 1.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit PWWP PF00855.12 CBZ08892.1 - 0.0011 19.0 0.1 0.0025 17.9 0.1 1.7 1 0 0 1 1 1 1 PWWP domain S-AdoMet_synt_C PF02773.11 CBZ08893.1 - 3e-70 234.3 0.2 4.9e-70 233.6 0.1 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 CBZ08893.1 - 5.3e-46 155.4 0.0 9.7e-45 151.3 0.0 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 CBZ08893.1 - 4.3e-40 135.9 0.2 8.6e-40 135.0 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Strep_pep PF14404.1 CBZ08893.1 - 0.032 14.4 0.0 0.081 13.1 0.0 1.6 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Streptomyces species MFS_2 PF13347.1 CBZ08894.1 - 1.7e-07 30.0 20.3 1.7e-07 30.0 14.0 2.2 1 1 1 2 2 2 1 MFS/sugar transport protein BT1 PF03092.11 CBZ08894.1 - 1.2e-06 27.5 20.9 1.2e-05 24.2 14.5 1.9 1 1 0 1 1 1 1 BT1 family UCH PF00443.24 CBZ08895.1 - 2.6e-43 148.0 0.0 3.8e-43 147.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBZ08895.1 - 8.5e-18 64.7 0.0 1.2e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 CBZ08895.1 - 5.8e-08 32.0 0.0 1.6e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 CBZ08895.1 - 0.032 14.4 0.1 0.098 12.9 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-like domain Polyoma_coat2 PF00761.15 CBZ08895.1 - 0.18 11.2 1.9 0.29 10.5 1.3 1.3 1 0 0 1 1 1 0 Polyomavirus coat protein DUF2051 PF09738.4 CBZ08895.1 - 0.46 9.7 1.7 0.58 9.3 0.6 1.5 2 0 0 2 2 2 0 Double stranded RNA binding protein (DUF2051) Aa_trans PF01490.13 CBZ08896.1 - 1.2e-33 116.1 14.0 1.7e-33 115.7 9.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CBZ08896.1 - 7.2e-08 31.6 10.5 7.2e-08 31.6 7.3 1.3 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family BBP1_C PF15272.1 CBZ08898.1 - 0.0036 16.8 2.8 0.0036 16.8 1.9 2.9 4 0 0 4 4 4 1 Spindle pole body component BBP1, C-terminal Filament PF00038.16 CBZ08898.1 - 0.0054 16.2 7.3 0.0054 16.2 5.1 4.7 5 0 0 5 5 5 3 Intermediate filament protein Reo_sigmaC PF04582.7 CBZ08898.1 - 0.38 9.8 14.7 0.18 10.9 2.6 3.4 3 1 0 3 3 3 0 Reovirus sigma C capsid protein DUF722 PF05263.6 CBZ08898.1 - 6.8 6.8 5.8 1.1 9.4 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF722) PGBA_C PF15437.1 CBZ08899.1 - 0.0015 18.5 4.9 0.0015 18.5 3.4 1.9 2 0 0 2 2 2 1 Plasminogen-binding protein pgbA C-terminal HsbA PF12296.3 CBZ08899.1 - 0.0026 17.5 0.5 2.8 7.7 0.1 2.7 3 0 0 3 3 3 2 Hydrophobic surface binding protein A CotJB PF12652.2 CBZ08899.1 - 0.0051 16.8 1.8 1.2 9.2 0.5 3.6 2 2 1 3 3 3 1 CotJB protein Toxin_52 PF15605.1 CBZ08899.1 - 0.068 13.0 2.3 2.7 7.9 0.2 3.1 3 0 0 3 3 3 0 Putative toxin 52 DUF4355 PF14265.1 CBZ08899.1 - 1.3 8.9 10.4 2.6 7.9 7.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4355) Aa_trans PF01490.13 CBZ08900.1 - 3e-42 144.5 18.4 4e-42 144.1 12.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CBZ08900.1 - 7.8e-08 31.5 9.5 7.8e-08 31.5 6.6 2.4 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Aa_trans PF01490.13 CBZ08901.1 - 8.5e-32 110.1 14.9 1.1e-31 109.7 10.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CBZ08901.1 - 5.9e-09 35.2 10.2 5.9e-09 35.2 7.0 1.5 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Aa_trans PF01490.13 CBZ08902.1 - 6.7e-43 146.6 18.1 8.9e-43 146.2 12.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CBZ08902.1 - 4.5e-09 35.6 9.9 4.5e-09 35.6 6.9 2.4 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family AA_permease_2 PF13520.1 CBZ08902.1 - 2.7e-07 29.4 25.7 2.7e-07 29.4 17.8 2.2 2 0 0 2 2 2 1 Amino acid permease Ribosomal_L40e PF01020.12 CBZ08904.1 - 4.5e-34 115.8 12.7 7.2e-34 115.1 8.8 1.3 1 0 0 1 1 1 1 Ribosomal L40e family ubiquitin PF00240.18 CBZ08904.1 - 5.9e-34 115.2 0.3 7.8e-34 114.9 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CBZ08904.1 - 2.1e-20 72.1 0.2 3e-20 71.6 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CBZ08904.1 - 7.9e-06 26.0 0.1 3.2e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CBZ08904.1 - 0.0003 20.5 0.0 0.00044 19.9 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CBZ08904.1 - 0.0094 15.8 0.1 0.019 14.8 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Zn_Tnp_IS91 PF14319.1 CBZ08904.1 - 0.063 12.7 2.2 0.091 12.2 1.5 1.3 1 0 0 1 1 1 0 Transposase zinc-binding domain DUF2870 PF11069.3 CBZ08904.1 - 0.071 13.1 0.0 0.14 12.2 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) zf-CHY PF05495.7 CBZ08904.1 - 0.099 12.8 3.3 0.15 12.2 2.3 1.2 1 0 0 1 1 1 0 CHY zinc finger DUF2407 PF10302.4 CBZ08904.1 - 0.099 12.8 0.0 0.12 12.6 0.0 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Ribosomal_L40e PF01020.12 CBZ08905.1 - 4.5e-34 115.8 12.7 7.2e-34 115.1 8.8 1.3 1 0 0 1 1 1 1 Ribosomal L40e family ubiquitin PF00240.18 CBZ08905.1 - 5.9e-34 115.2 0.3 7.8e-34 114.9 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CBZ08905.1 - 2.1e-20 72.1 0.2 3e-20 71.6 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CBZ08905.1 - 7.9e-06 26.0 0.1 3.2e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CBZ08905.1 - 0.0003 20.5 0.0 0.00044 19.9 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CBZ08905.1 - 0.0094 15.8 0.1 0.019 14.8 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Zn_Tnp_IS91 PF14319.1 CBZ08905.1 - 0.063 12.7 2.2 0.091 12.2 1.5 1.3 1 0 0 1 1 1 0 Transposase zinc-binding domain DUF2870 PF11069.3 CBZ08905.1 - 0.071 13.1 0.0 0.14 12.2 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) zf-CHY PF05495.7 CBZ08905.1 - 0.099 12.8 3.3 0.15 12.2 2.3 1.2 1 0 0 1 1 1 0 CHY zinc finger DUF2407 PF10302.4 CBZ08905.1 - 0.099 12.8 0.0 0.12 12.6 0.0 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Arf PF00025.16 CBZ08906.1 - 7.8e-75 249.9 0.2 8.9e-75 249.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CBZ08906.1 - 3.6e-14 52.4 0.0 4.3e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CBZ08906.1 - 1.5e-13 50.4 0.0 1.7e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CBZ08906.1 - 7.1e-11 41.4 0.2 4e-08 32.3 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 CBZ08906.1 - 2.1e-09 37.9 0.0 2.8e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 CBZ08906.1 - 7.8e-08 31.7 0.0 9.7e-08 31.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBZ08906.1 - 1.2e-05 25.2 0.1 2e-05 24.5 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 CBZ08906.1 - 0.00082 18.5 0.1 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 CBZ08906.1 - 0.0011 18.4 0.1 0.014 14.7 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 CBZ08906.1 - 0.014 15.3 0.2 0.017 14.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CBZ08906.1 - 0.14 12.0 0.5 3.8 7.4 0.0 2.1 1 1 0 2 2 2 0 AAA domain Pyr_redox_2 PF07992.9 CBZ08908.1 - 4.3e-30 105.1 0.0 5.6e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 CBZ08908.1 - 8.1e-20 70.9 0.2 3.3e-19 68.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 CBZ08908.1 - 2.6e-17 62.9 0.9 7e-13 48.7 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CBZ08908.1 - 1.2e-10 41.1 1.0 1.7e-10 40.5 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CBZ08908.1 - 4.2e-10 40.0 0.1 5.6e-08 33.1 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CBZ08908.1 - 6.8e-09 35.6 2.2 8.7e-05 22.4 0.3 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 CBZ08908.1 - 3.2e-08 32.8 1.2 7.1e-06 25.1 0.3 2.9 2 1 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.19 CBZ08908.1 - 1.3e-07 30.8 5.0 4.9e-06 25.6 0.1 2.9 2 1 1 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.9 CBZ08908.1 - 5e-07 28.5 1.9 7e-06 24.7 0.2 2.9 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.12 CBZ08908.1 - 1.6e-06 27.3 0.5 0.00031 19.8 0.0 2.6 3 0 0 3 3 3 1 Thi4 family FAD_binding_2 PF00890.19 CBZ08908.1 - 2.1e-06 26.8 0.6 2.1e-06 26.8 0.4 2.5 3 0 0 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.7 CBZ08908.1 - 6.8e-06 25.2 0.7 0.00055 18.9 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 CBZ08908.1 - 2.3e-05 23.5 0.3 0.0033 16.5 0.0 3.0 3 0 0 3 3 3 1 FAD binding domain K_oxygenase PF13434.1 CBZ08908.1 - 0.0021 17.0 0.0 0.041 12.7 0.0 2.3 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) ThiF PF00899.16 CBZ08908.1 - 0.0075 16.0 0.1 0.045 13.5 0.0 2.4 2 0 0 2 2 2 1 ThiF family NAD_binding_9 PF13454.1 CBZ08908.1 - 0.01 15.6 0.1 0.11 12.2 0.0 2.6 2 1 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.13 CBZ08908.1 - 0.022 14.7 1.6 1.6 8.7 0.1 3.1 3 0 0 3 3 3 0 TrkA-N domain NAD_binding_7 PF13241.1 CBZ08908.1 - 0.2 11.9 0.8 1.6 9.0 0.1 2.7 3 1 0 3 3 3 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 CBZ08908.1 - 0.29 10.7 3.6 1.7 8.2 0.0 3.3 4 1 0 4 4 4 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Prok-TraM PF09228.5 CBZ08911.1 - 0.046 13.8 0.0 0.084 13.0 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM PGC7_Stella PF15549.1 CBZ08911.1 - 0.22 11.5 3.7 0.35 10.8 2.5 1.3 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain CTP_transf_1 PF01148.15 CBZ08919.1 - 1.2e-31 110.2 8.3 1.1e-28 100.6 0.1 3.4 4 0 0 4 4 4 2 Cytidylyltransferase family Voltage_CLC PF00654.15 CBZ08921.1 - 7.1e-79 265.4 25.8 2e-78 263.8 16.9 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 CBZ08921.1 - 1.6e-09 37.3 0.9 0.00012 21.8 0.2 2.5 2 0 0 2 2 2 2 CBS domain DUF503 PF04456.7 CBZ08922.1 - 0.023 14.2 0.7 0.066 12.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF503) DNA_pack_N PF02500.10 CBZ08922.1 - 0.79 9.2 2.9 0.7 9.3 1.1 1.5 1 1 1 2 2 2 0 Probable DNA packing protein, N-terminus Glycos_transf_2 PF00535.21 CBZ08923.1 - 7.7e-08 32.1 0.0 1.5e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 RecX PF02631.11 CBZ08924.1 - 0.15 12.2 0.9 0.25 11.5 0.6 1.3 1 0 0 1 1 1 0 RecX family Mpv17_PMP22 PF04117.7 CBZ08925.1 - 1e-13 50.6 0.7 2.5e-13 49.4 0.5 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family HSP90 PF00183.13 CBZ08926.1 - 1.2e-260 865.4 30.0 1.4e-260 865.2 20.8 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 CBZ08926.1 - 1.8e-13 50.2 0.4 8.5e-13 48.1 0.0 2.4 1 1 1 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CBZ08926.1 - 6.4e-13 48.3 0.0 1.2e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Tom37_C PF11801.3 CBZ08926.1 - 0.39 10.5 13.5 0.099 12.5 2.2 2.7 3 0 0 3 3 3 0 Tom37 C-terminal domain HSP90 PF00183.13 CBZ08927.1 - 3.1e-261 867.3 32.9 3.7e-261 867.1 22.8 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 CBZ08927.1 - 5.5e-13 48.7 0.3 3.1e-12 46.3 0.1 2.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CBZ08927.1 - 6.4e-13 48.3 0.0 1.2e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_S20p PF01649.13 CBZ08927.1 - 0.13 12.6 6.0 0.42 11.0 0.6 3.3 3 0 0 3 3 3 0 Ribosomal protein S20 Tom37_C PF11801.3 CBZ08927.1 - 1.1 9.0 14.5 0.19 11.5 2.7 2.8 3 0 0 3 3 3 0 Tom37 C-terminal domain HSP90 PF00183.13 CBZ08928.1 - 3.1e-261 867.3 32.9 3.7e-261 867.1 22.8 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 CBZ08928.1 - 5.5e-13 48.7 0.3 3.1e-12 46.3 0.1 2.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CBZ08928.1 - 6.4e-13 48.3 0.0 1.2e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_S20p PF01649.13 CBZ08928.1 - 0.13 12.6 6.0 0.42 11.0 0.6 3.3 3 0 0 3 3 3 0 Ribosomal protein S20 Tom37_C PF11801.3 CBZ08928.1 - 1.1 9.0 14.5 0.19 11.5 2.7 2.8 3 0 0 3 3 3 0 Tom37 C-terminal domain PTP_N PF12453.3 CBZ08931.1 - 0.17 11.4 1.6 0.7 9.5 1.1 2.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase N terminal PRA1 PF03208.14 CBZ08933.1 - 2.7e-22 78.7 1.3 4.7e-22 77.9 0.9 1.3 1 0 0 1 1 1 1 PRA1 family protein UbiA PF01040.13 CBZ08933.1 - 0.0013 17.9 1.5 0.0018 17.5 1.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family TAS2R PF05296.8 CBZ08933.1 - 0.047 12.5 6.6 0.094 11.5 4.6 1.5 1 1 0 1 1 1 0 Mammalian taste receptor protein (TAS2R) MASE2 PF05230.6 CBZ08933.1 - 0.18 11.8 2.4 0.29 11.1 1.3 1.7 1 1 0 1 1 1 0 MASE2 domain IQ PF00612.22 CBZ08936.1 - 0.00033 20.0 0.1 0.0011 18.4 0.1 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif FliT PF05400.8 CBZ08936.1 - 8 6.9 8.4 5.9 7.3 0.4 2.9 2 1 0 2 2 2 0 Flagellar protein FliT Ribosomal_L37e PF01907.14 CBZ08937.1 - 5.1e-27 93.4 8.6 8.5e-27 92.7 5.9 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e zinc_ribbon_6 PF14599.1 CBZ08937.1 - 0.037 13.8 0.5 0.057 13.2 0.4 1.3 1 0 0 1 1 1 0 Zinc-ribbon DZR PF12773.2 CBZ08937.1 - 0.09 12.6 0.6 0.15 11.8 0.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon DUF1279 PF06916.8 CBZ08938.1 - 0.45 10.8 0.1 0.45 10.8 0.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1279) SOG2 PF10428.4 CBZ08938.1 - 0.47 9.0 3.4 0.56 8.7 2.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF1279 PF06916.8 CBZ08939.1 - 0.0042 17.3 0.1 0.0077 16.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) PaaSYMP PF14738.1 CBZ08940.1 - 8.8e-48 161.9 2.3 8.8e-48 161.9 1.6 2.3 2 1 0 2 2 2 1 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 DUF572 PF04502.8 CBZ08940.1 - 0.011 14.9 0.2 0.011 14.9 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF3720 PF12517.3 CBZ08941.1 - 0.043 14.5 2.5 5.7 7.6 0.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3720) Baculo_IE-1 PF05290.6 CBZ08943.1 - 0.00093 18.9 1.9 0.0015 18.2 1.3 1.3 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) SelB-wing_1 PF09105.5 CBZ08943.1 - 0.11 12.2 0.0 0.28 10.8 0.0 1.7 1 0 0 1 1 1 0 Elongation factor SelB, winged helix zf-C3HC4_3 PF13920.1 CBZ08943.1 - 0.5 10.0 14.2 1 9.0 9.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ08943.1 - 3.1 7.9 14.0 4.9 7.2 9.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBZ08943.1 - 3.2 7.4 12.4 8.7 6.0 8.6 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.1 CBZ08943.1 - 5 7.0 13.9 8.3 6.3 9.6 1.4 1 0 0 1 1 1 0 Ring finger domain Glyco_hydro_85 PF03644.8 CBZ08944.1 - 6e-104 347.5 0.0 8.1e-104 347.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Peptidase_C97 PF05903.9 CBZ08944.1 - 3.7e-21 75.4 0.0 6e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUB PF09409.5 CBZ08944.1 - 4.8e-12 45.4 0.0 9.1e-12 44.5 0.0 1.5 1 0 0 1 1 1 1 PUB domain DUF3421 PF11901.3 CBZ08944.1 - 6.6e-07 29.0 0.4 0.00091 18.9 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF3421) Glyco_hydro_18 PF00704.23 CBZ08944.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 18 DUF1241 PF06840.6 CBZ08945.1 - 1.2e-07 31.0 13.9 0.21 10.8 0.3 5.1 1 1 4 5 5 5 5 Protein of unknown function (DUF1241) DUF1136 PF06582.7 CBZ08945.1 - 2e-05 24.1 6.6 1.4e+02 2.3 0.0 8.3 8 0 0 8 8 8 0 Repeat of unknown function (DUF1136) FlxA PF14282.1 CBZ08945.1 - 0.19 11.6 12.7 0.037 13.9 3.9 3.1 2 0 0 2 2 2 0 FlxA-like protein zf-MYND PF01753.13 CBZ08946.1 - 8.8e-08 31.8 10.4 8.8e-08 31.8 7.2 2.0 2 0 0 2 2 2 1 MYND finger Epimerase PF01370.16 CBZ08948.1 - 1.4e-37 129.4 0.0 2.3e-37 128.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 CBZ08948.1 - 1.4e-14 53.7 0.0 1.5e-13 50.2 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase_Csub PF13950.1 CBZ08948.1 - 3.4e-12 46.1 0.0 7.2e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 CBZ08948.1 - 6.9e-09 34.8 0.0 3.5e-08 32.4 0.0 2.0 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CBZ08948.1 - 1.9e-08 33.5 0.0 5.6e-08 32.0 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 CBZ08948.1 - 9.5e-05 22.1 0.0 0.00046 19.9 0.0 2.0 2 1 0 2 2 2 1 KR domain RmlD_sub_bind PF04321.12 CBZ08948.1 - 0.00019 20.4 0.0 0.0015 17.4 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 CBZ08948.1 - 0.00039 20.3 0.0 0.00098 19.0 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase DUF1800 PF08811.6 CBZ08948.1 - 0.053 12.4 0.0 0.08 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) CDC45 PF02724.9 CBZ08950.1 - 3.2e-131 438.4 0.0 3.6e-131 438.2 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein UPF0561 PF10573.4 CBZ08950.1 - 0.14 12.0 6.4 0.35 10.7 4.4 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 TGF_beta_GS PF08515.7 CBZ08950.1 - 0.72 9.2 4.8 1.7 8.0 3.3 1.6 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif CoA_trans PF01144.18 CBZ08952.1 - 4.7e-98 326.6 1.7 1.2e-60 204.4 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 CBZ08952.1 - 0.0078 15.9 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain RabGAP-TBC PF00566.13 CBZ08953.1 - 9.6e-08 31.7 0.5 1.5e-07 31.0 0.4 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rhodanese PF00581.15 CBZ08953.1 - 0.0038 17.5 0.0 0.01 16.1 0.0 1.7 1 1 0 1 1 1 1 Rhodanese-like domain NCA2 PF08637.5 CBZ08954.1 - 4.3e-37 127.5 0.1 5.4e-29 101.0 0.0 2.2 2 0 0 2 2 2 2 ATP synthase regulation protein NCA2 GRASP55_65 PF04495.9 CBZ08956.1 - 8.5e-46 155.3 0.0 8.1e-40 136.0 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain HSP90 PF00183.13 CBZ08957.1 - 1.5e-72 244.7 2.6 9.1e-72 242.1 0.6 2.0 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.1 CBZ08957.1 - 2e-12 46.9 0.1 4.6e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CBZ08957.1 - 5.4e-06 26.0 0.0 1.2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ski_Sno PF02437.12 CBZ08957.1 - 0.078 12.5 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 SKI/SNO/DAC family MMR_HSR1 PF01926.18 CBZ08958.1 - 3.1e-19 69.0 0.0 1.4e-13 50.7 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CBZ08958.1 - 2.8e-11 42.9 0.9 6.2e-09 35.3 0.1 2.5 3 0 0 3 3 3 2 Ferrous iron transport protein B GTP_EFTU PF00009.22 CBZ08958.1 - 3.8e-05 23.2 0.1 0.0015 17.9 0.0 2.5 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CBZ08958.1 - 0.0006 19.6 0.5 0.038 13.8 0.1 2.9 2 1 1 3 3 3 1 Dynamin family DUF258 PF03193.11 CBZ08958.1 - 0.0021 17.2 0.1 0.028 13.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ArgK PF03308.11 CBZ08958.1 - 0.018 13.8 0.5 0.09 11.5 0.0 2.2 2 0 0 2 2 2 0 ArgK protein Miro PF08477.8 CBZ08958.1 - 0.02 15.4 0.1 1.1 9.7 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein Taeniidae_ag PF05596.6 CBZ08958.1 - 0.039 13.7 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Taeniidae antigen AAA_17 PF13207.1 CBZ08958.1 - 0.059 14.1 0.2 0.28 12.0 0.0 2.2 3 0 0 3 3 3 0 AAA domain Diphthamide_syn PF01866.12 CBZ08959.1 - 2e-33 115.9 0.2 5e-19 68.6 0.0 2.3 2 0 0 2 2 2 2 Putative diphthamide synthesis protein zf-MYND PF01753.13 CBZ08960.1 - 8.8e-09 35.1 45.9 3.4e-05 23.6 12.1 3.1 3 0 0 3 3 3 2 MYND finger zf-C3HC PF07967.8 CBZ08963.1 - 0.0054 16.4 1.8 1.6 8.5 0.1 3.0 3 0 0 3 3 3 2 C3HC zinc finger-like Glyco_tran_WecB PF03808.8 CBZ08964.1 - 0.014 14.7 0.4 0.71 9.2 0.1 2.5 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Tox-WTIP PF15654.1 CBZ08965.1 - 0.024 14.2 0.2 0.024 14.2 0.1 2.2 2 0 0 2 2 2 0 Toxin with a conserved tryptophan and TIP tripeptide motif Bax1-I PF01027.15 CBZ08965.1 - 0.31 10.6 13.1 0.74 9.3 9.1 1.7 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 KorB PF08535.5 CBZ08966.1 - 0.088 12.9 0.0 0.31 11.2 0.0 1.9 1 1 0 1 1 1 0 KorB domain MinC_N PF05209.8 CBZ08966.1 - 0.11 12.3 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Septum formation inhibitor MinC, N-terminal domain DinB_2 PF12867.2 CBZ08966.1 - 0.21 11.9 2.4 9.1 6.6 0.4 3.3 2 1 0 2 2 2 0 DinB superfamily Rad51 PF08423.6 CBZ08967.1 - 1.4e-24 86.4 0.2 1.4e-17 63.4 0.1 3.7 4 0 0 4 4 4 3 Rad51 AAA_25 PF13481.1 CBZ08967.1 - 5.4e-12 45.5 0.0 1.7e-11 43.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 CBZ08967.1 - 6.3e-05 22.1 0.0 0.00012 21.3 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 CBZ08967.1 - 8.6e-05 21.7 0.2 0.00021 20.5 0.1 1.6 1 0 0 1 1 1 1 KaiC AAA_19 PF13245.1 CBZ08967.1 - 0.00032 20.3 0.5 0.0013 18.4 0.1 2.3 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 CBZ08967.1 - 0.086 12.4 0.0 0.38 10.3 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA PF00004.24 CBZ08967.1 - 0.11 12.6 0.0 0.35 11.0 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Radial_spoke PF04712.7 CBZ08968.1 - 3e-09 36.1 0.0 2.4e-07 29.8 0.0 2.6 3 0 0 3 3 3 2 Radial spokehead-like protein UDPGP PF01704.13 CBZ08970.1 - 7.4e-24 84.0 0.0 1e-22 80.2 0.0 2.0 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 CBZ08970.1 - 0.0026 17.8 3.6 0.0066 16.5 0.6 2.8 2 1 1 3 3 3 1 MobA-like NTP transferase domain SpoIIE PF07228.7 CBZ08972.1 - 2.6e-09 37.0 0.0 3.3e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 CBZ08972.1 - 8.8e-05 22.0 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 CBZ08972.1 - 0.048 13.0 0.0 0.094 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein phosphatase 2C CBF PF03914.12 CBZ08973.1 - 1.2e-36 125.6 0.2 1.9e-36 125.0 0.1 1.3 1 0 0 1 1 1 1 CBF/Mak21 family NAD_binding_10 PF13460.1 CBZ08975.1 - 0.00013 22.0 0.1 0.00045 20.2 0.1 1.9 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 CBZ08975.1 - 0.00052 19.3 0.1 0.0021 17.3 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family 3HCDH_N PF02737.13 CBZ08975.1 - 0.0062 16.2 0.0 0.0092 15.6 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 CBZ08975.1 - 0.012 15.6 0.1 0.021 14.9 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_4 PF07993.7 CBZ08975.1 - 0.025 13.4 0.0 0.04 12.8 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein HNF-1_N PF04814.8 CBZ08976.1 - 0.023 14.7 0.7 0.033 14.3 0.5 1.2 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus BTV_NS2 PF04514.7 CBZ08976.1 - 0.32 9.8 5.8 0.42 9.4 4.0 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 COX16 PF14138.1 CBZ08976.1 - 3.2 8.0 5.2 1.3 9.2 1.8 1.6 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 Metallophos PF00149.23 CBZ08977.1 - 4e-37 127.5 0.4 4.8e-37 127.2 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.23 CBZ08978.1 - 4.9e-37 127.2 0.4 6e-37 126.9 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.23 CBZ08979.1 - 2.2e-36 125.1 0.3 3e-36 124.6 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.23 CBZ08980.1 - 2.3e-36 125.1 0.3 3.1e-36 124.6 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Amastin PF07344.6 CBZ08981.1 - 2.8e-59 199.1 4.7 3.3e-59 198.9 3.2 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ08981.1 - 0.00042 20.0 5.7 0.00042 20.0 3.9 1.7 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 CBZ08981.1 - 0.16 11.5 6.6 0.4 10.3 4.6 1.8 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Amastin PF07344.6 CBZ08982.1 - 2.8e-59 199.1 4.7 3.3e-59 198.9 3.2 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ08982.1 - 0.00042 20.0 5.7 0.00042 20.0 3.9 1.7 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 CBZ08982.1 - 0.16 11.5 6.6 0.4 10.3 4.6 1.8 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Helicase_C PF00271.26 CBZ08983.1 - 9.4e-06 25.4 0.0 4.6e-05 23.1 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBZ08983.1 - 4.5e-05 22.9 0.0 7.7e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.1 CBZ08983.1 - 0.064 13.0 1.1 0.17 11.6 0.2 2.1 2 0 0 2 2 2 0 Part of AAA domain FtsX PF02687.16 CBZ08984.1 - 1.5e-23 82.8 34.3 4.3e-16 58.7 9.0 5.3 4 1 1 5 5 5 2 FtsX-like permease family OSTbeta PF15048.1 CBZ08984.1 - 0.49 10.4 0.0 0.49 10.4 0.0 2.3 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein AAA_13 PF13166.1 CBZ08986.1 - 9.3e-06 24.4 59.0 0.00079 18.0 7.9 4.8 3 1 2 5 5 5 4 AAA domain Rootletin PF15035.1 CBZ08986.1 - 0.0015 18.5 23.1 0.0015 18.5 16.0 6.7 3 1 3 7 7 7 2 Ciliary rootlet component, centrosome cohesion MscS_porin PF12795.2 CBZ08986.1 - 0.02 14.1 0.6 0.02 14.1 0.4 6.6 3 1 1 5 5 5 0 Mechanosensitive ion channel porin domain Tht1 PF04163.7 CBZ08986.1 - 1.7 6.9 13.7 10 4.4 0.1 2.3 2 0 0 2 2 2 0 Tht1-like nuclear fusion protein Reo_sigmaC PF04582.7 CBZ08986.1 - 1.8 7.6 17.9 4.8 6.2 0.8 5.0 3 1 2 6 6 6 0 Reovirus sigma C capsid protein APG6 PF04111.7 CBZ08986.1 - 2 7.3 95.8 0.42 9.6 13.0 7.1 4 1 3 7 7 7 0 Autophagy protein Apg6 DUF2997 PF11211.3 CBZ08986.1 - 2.9 7.3 8.8 3.1 7.2 0.7 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2997) Amastin PF07344.6 CBZ08987.1 - 6.3e-49 165.5 7.2 7.5e-49 165.3 5.0 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF4337 PF14235.1 CBZ08987.1 - 0.0018 18.1 0.6 0.0029 17.4 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4337) Claudin_2 PF13903.1 CBZ08987.1 - 0.17 11.5 17.3 0.02 14.5 7.7 2.3 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 CBZ08987.1 - 1.1 8.9 11.5 12 5.5 7.7 2.7 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Ank_2 PF12796.2 CBZ08989.1 - 6.7e-21 74.4 2.9 8e-10 38.9 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBZ08989.1 - 7.3e-15 53.9 4.9 0.00016 21.3 0.0 5.3 4 1 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 CBZ08989.1 - 8.1e-14 51.7 5.1 1.2e-05 25.6 0.2 4.4 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBZ08989.1 - 8.8e-14 51.2 11.8 3.4e-05 23.9 0.1 4.9 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ08989.1 - 8.9e-13 47.1 1.7 0.0093 16.1 0.0 5.1 4 0 0 4 4 4 4 Ankyrin repeat ECH PF00378.15 CBZ08990.1 - 7.5e-51 172.6 3.1 4.3e-50 170.1 2.2 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family LRR_4 PF12799.2 CBZ08992.1 - 4e-12 45.4 12.0 1.3e-07 31.0 2.0 5.3 4 1 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ08992.1 - 2e-08 33.8 12.3 1.2e-06 28.1 2.9 3.7 3 1 2 5 5 5 3 Leucine rich repeat LRR_1 PF00560.28 CBZ08992.1 - 0.00026 20.5 6.8 1.9 8.8 0.2 5.4 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_7 PF13504.1 CBZ08992.1 - 0.033 14.3 4.7 13 6.4 0.1 4.7 5 0 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 CBZ08992.1 - 0.091 12.8 1.8 1.5 9.1 0.2 3.1 3 0 0 3 3 3 0 Leucine Rich repeat LRR_4 PF12799.2 CBZ08993.1 - 1.7e-10 40.3 0.7 0.0005 19.6 0.0 2.4 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBZ08993.1 - 2.3e-09 35.9 1.3 2.7 8.3 0.1 5.2 5 0 0 5 5 5 4 Leucine Rich Repeat LRR_8 PF13855.1 CBZ08993.1 - 1.6e-08 34.1 0.6 0.0018 17.9 0.0 2.3 2 0 0 2 2 2 2 Leucine rich repeat LRR_6 PF13516.1 CBZ08993.1 - 6.6e-05 22.5 1.2 3.8 7.8 0.1 4.3 4 0 0 4 4 4 1 Leucine Rich repeat LRR_7 PF13504.1 CBZ08993.1 - 0.0068 16.4 3.1 37 5.1 0.1 4.6 4 0 0 4 4 4 0 Leucine rich repeat Cornifin PF02389.10 CBZ08993.1 - 0.94 9.2 43.6 4.9 6.8 13.6 2.2 1 1 1 2 2 2 0 Cornifin (SPRR) family Metallophos PF00149.23 CBZ08994.1 - 0.019 14.3 0.0 0.072 12.4 0.0 2.0 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase STT3 PF02516.9 CBZ08997.1 - 2.9e-48 165.0 23.9 8.4e-47 160.2 16.5 2.1 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit VirB8 PF04335.8 CBZ08997.1 - 4.2 6.8 5.6 0.42 10.1 0.2 2.1 2 0 0 2 2 2 0 VirB8 protein Ribosomal_L18p PF00861.17 CBZ08999.1 - 4.2e-38 130.1 0.6 4.2e-38 130.1 0.4 1.9 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 CBZ08999.1 - 2.7e-23 82.3 4.7 2.7e-23 82.3 3.3 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L15e PF00827.12 CBZ09000.1 - 6.8e-90 299.7 9.1 7.7e-90 299.5 6.3 1.0 1 0 0 1 1 1 1 Ribosomal L15 MBOAT PF03062.14 CBZ09003.1 - 4.2e-31 108.2 16.4 6.6e-31 107.6 11.4 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT PF03062.14 CBZ09004.1 - 2.8e-30 105.5 21.9 6e-30 104.4 15.2 1.5 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT PF03062.14 CBZ09005.1 - 1.9e-30 106.1 22.3 3e-30 105.4 15.5 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Synaptobrevin PF00957.16 CBZ09006.1 - 5.8e-14 51.4 0.1 9.9e-14 50.7 0.1 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 CBZ09006.1 - 7.3e-10 38.2 0.0 1.1e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF605 PF04652.11 CBZ09007.1 - 0.016 14.6 12.8 0.02 14.3 8.9 1.1 1 0 0 1 1 1 0 Vta1 like CDC45 PF02724.9 CBZ09007.1 - 0.019 13.0 1.0 0.02 12.9 0.7 1.1 1 0 0 1 1 1 0 CDC45-like protein COPI_C PF06957.6 CBZ09007.1 - 0.11 11.0 3.0 0.14 10.6 2.1 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Nop14 PF04147.7 CBZ09007.1 - 2.2 6.0 13.5 3.1 5.6 9.4 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 CBZ09007.1 - 6.8 5.8 13.9 9.7 5.3 9.6 1.2 1 0 0 1 1 1 0 SDA1 TSP9 PF11493.3 CBZ09007.1 - 8.5 7.0 7.6 11 6.6 4.4 1.9 1 1 0 1 1 1 0 Thylakoid soluble phosphoprotein TSP9 DUF2984 PF11203.3 CBZ09008.1 - 0.0033 17.4 3.0 0.0055 16.7 1.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2984) PGAP1 PF07819.8 CBZ09009.1 - 0.00027 20.6 0.0 0.00052 19.6 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 CBZ09009.1 - 0.00031 20.3 0.0 0.001 18.7 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) Thioesterase PF00975.15 CBZ09009.1 - 0.02 15.1 0.1 0.075 13.2 0.0 2.0 2 0 0 2 2 2 0 Thioesterase domain Phosphoprotein PF00922.12 CBZ09009.1 - 0.081 12.1 0.6 0.14 11.3 0.4 1.3 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein adh_short PF00106.20 CBZ09010.1 - 3.8e-11 43.1 0.2 1.3e-10 41.4 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase HTH_8 PF02954.14 CBZ09010.1 - 0.022 14.2 0.0 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family A_deaminase PF00962.17 CBZ09011.1 - 5.1e-57 193.2 0.0 6.1e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase adh_short PF00106.20 CBZ09012.1 - 3.6e-12 46.5 1.5 4.1e-11 43.0 1.1 2.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBZ09012.1 - 0.00011 21.9 1.7 0.00023 20.8 0.9 1.8 2 0 0 2 2 2 1 KR domain 3HCDH_N PF02737.13 CBZ09012.1 - 0.0085 15.7 0.2 0.016 14.9 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 CBZ09012.1 - 0.01 14.9 0.1 0.021 13.8 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1761 PF08570.5 CBZ09012.1 - 0.016 15.1 1.6 7.4 6.5 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1761) NmrA PF05368.8 CBZ09012.1 - 0.02 14.1 0.1 0.088 12.0 0.1 1.9 2 0 0 2 2 2 0 NmrA-like family adh_short_C2 PF13561.1 CBZ09012.1 - 0.038 13.7 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CBZ09012.1 - 0.044 13.7 0.2 0.1 12.5 0.2 1.6 1 1 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 CBZ09012.1 - 0.067 12.9 0.1 0.17 11.7 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Ribosomal_L11_N PF03946.9 CBZ09014.1 - 7.1e-15 54.2 0.2 1.2e-14 53.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 CBZ09014.1 - 2.4e-11 43.6 0.5 4.5e-11 42.7 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain RRM_1 PF00076.17 CBZ09015.1 - 4.8e-36 122.2 0.0 4.6e-17 61.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ09015.1 - 2.3e-29 101.1 0.1 3.9e-14 52.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ09015.1 - 2.5e-10 40.0 0.0 4.5e-05 23.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CBZ09015.1 - 0.00018 21.1 0.4 1.4 8.7 0.0 3.6 3 1 0 3 3 3 2 Limkain b1 IQ PF00612.22 CBZ09017.1 - 0.00068 19.0 1.5 0.002 17.5 1.0 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF4492 PF14899.1 CBZ09018.1 - 0.011 15.2 0.2 0.019 14.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) DUF3753 PF12575.3 CBZ09018.1 - 0.043 13.5 1.4 0.1 12.3 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) FAM163 PF15069.1 CBZ09018.1 - 0.061 13.8 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 FAM163 family SCIMP PF15050.1 CBZ09018.1 - 0.097 12.5 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 SCIMP protein GP41 PF00517.12 CBZ09018.1 - 0.099 12.1 0.5 0.16 11.5 0.4 1.2 1 0 0 1 1 1 0 Retroviral envelope protein ATP-synt_8 PF00895.15 CBZ09018.1 - 0.49 10.6 2.8 1.4 9.1 1.9 1.7 1 0 0 1 1 1 0 ATP synthase protein 8 DUF912 PF06024.7 CBZ09018.1 - 3.7 7.6 4.6 0.52 10.3 0.1 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Aminotran_5 PF00266.14 CBZ09019.1 - 1.1e-49 169.1 0.1 4.4e-31 107.9 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.16 CBZ09019.1 - 0.0026 16.9 0.1 0.0079 15.3 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Ribosomal_L31e PF01198.14 CBZ09020.1 - 3.4e-28 97.1 0.4 7.3e-28 96.0 0.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L31e MatE PF01554.13 CBZ09021.1 - 1.5e-29 102.7 25.0 1.1e-15 57.6 7.6 2.2 2 0 0 2 2 2 2 MatE Pkinase PF00069.20 CBZ09023.1 - 1.6e-08 34.0 0.0 1.2e-06 27.8 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ09023.1 - 0.0017 17.5 0.0 0.0038 16.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase BRCT PF00533.21 CBZ09025.1 - 7.6e-10 38.8 0.0 0.00011 22.2 0.0 2.5 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain ArsD PF06953.6 CBZ09025.1 - 0.098 12.8 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 Arsenical resistance operon trans-acting repressor ArsD zf-CCCH PF00642.19 CBZ09026.1 - 0.0014 18.2 4.4 0.0024 17.4 3.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) GTP_EFTU PF00009.22 CBZ09027.1 - 2.4e-61 206.4 0.4 3.7e-61 205.8 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CBZ09027.1 - 2.8e-36 123.7 0.0 7.3e-36 122.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 CBZ09027.1 - 7.3e-21 73.8 0.0 3.2e-20 71.7 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.1 CBZ09027.1 - 7.8e-14 51.2 0.1 3.5e-13 49.2 0.0 2.0 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 CBZ09027.1 - 3.2e-13 49.5 0.1 8.8e-13 48.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 PepSY_TM PF03929.11 CBZ09029.1 - 0.2 12.1 2.0 0.38 11.2 1.4 1.4 1 0 0 1 1 1 0 PepSY-associated TM helix TLD PF07534.11 CBZ09032.1 - 3.1e-23 82.2 0.1 4.3e-22 78.5 0.0 2.1 1 1 0 1 1 1 1 TLD ubiquitin PF00240.18 CBZ09034.1 - 9.3e-299 963.6 44.2 1.7e-32 110.6 0.2 9.0 9 0 0 9 9 9 9 Ubiquitin family Rad60-SLD PF11976.3 CBZ09034.1 - 5.9e-178 576.9 41.8 6.7e-19 67.3 0.2 9.0 9 0 0 9 9 9 9 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CBZ09034.1 - 1.6e-53 178.9 18.2 0.0006 20.0 0.0 11.6 9 9 0 9 9 9 9 Ubiquitin-like domain DUF2870 PF11069.3 CBZ09034.1 - 1.1e-24 86.2 0.2 2.4 8.2 0.0 9.7 9 0 0 9 9 9 9 Protein of unknown function (DUF2870) Rad60-SLD_2 PF13881.1 CBZ09034.1 - 1.9e-24 85.7 16.2 0.7 9.7 0.0 10.1 9 0 0 9 9 9 9 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CBZ09034.1 - 5.5e-22 77.7 5.0 3.4 7.9 0.0 9.1 1 1 5 9 9 9 9 DUF2407 ubiquitin-like domain TUG-UBL1 PF11470.3 CBZ09034.1 - 8.3e-19 67.2 10.2 4.4 7.2 0.0 9.2 9 0 0 9 9 9 9 GLUT4 regulating protein TUG FlgD_ig PF13860.1 CBZ09034.1 - 1.5e-11 43.8 11.2 28 4.5 0.0 9.1 9 0 0 9 9 9 0 FlgD Ig-like domain USP7_C2 PF14533.1 CBZ09034.1 - 1.6e-09 37.5 15.7 20 4.5 0.0 8.6 1 1 1 9 9 9 0 Ubiquitin-specific protease C-terminal CTDII PF01556.13 CBZ09034.1 - 1.2e-06 28.2 33.7 13 5.7 0.1 9.2 2 1 6 9 9 9 2 DnaJ C terminal domain Plexin_cytopl PF08337.7 CBZ09034.1 - 0.00068 18.0 26.1 20 3.3 0.1 10.6 10 7 0 10 10 10 0 Plexin cytoplasmic RasGAP domain WD40 PF00400.27 CBZ09036.1 - 1.7e-10 40.3 9.2 0.00097 18.9 0.0 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat Phospholamban PF04272.9 CBZ09037.1 - 0.016 14.6 0.1 0.053 12.9 0.1 1.9 1 0 0 1 1 1 0 Phospholamban PSP1 PF04468.7 CBZ09038.1 - 2.7e-30 104.1 0.4 4.4e-30 103.5 0.3 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Ham1p_like PF01725.11 CBZ09039.1 - 1.5e-54 184.2 0.0 1.7e-54 184.0 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Peripla_BP_4 PF13407.1 CBZ09040.1 - 0.0074 15.6 0.1 0.056 12.7 0.0 2.1 2 0 0 2 2 2 1 Periplasmic binding protein domain DUF2316 PF10078.4 CBZ09040.1 - 0.093 12.7 0.4 0.93 9.5 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) DUF945 PF06097.6 CBZ09043.1 - 0.0086 14.8 0.1 0.013 14.3 0.1 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF945) Nitroreductase PF00881.19 CBZ09044.1 - 5.7e-11 42.5 0.2 6.9e-11 42.2 0.1 1.1 1 0 0 1 1 1 1 Nitroreductase family Picorna_P3A PF06363.6 CBZ09044.1 - 0.068 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Picornaviridae P3A protein AAA_17 PF13207.1 CBZ09045.1 - 2.6e-09 37.9 0.0 0.00038 21.2 0.0 3.6 2 0 0 2 2 2 2 AAA domain YHS PF04945.8 CBZ09045.1 - 1.3e-05 24.8 2.2 0.18 11.6 0.3 4.1 4 0 0 4 4 4 2 YHS domain AAA_18 PF13238.1 CBZ09045.1 - 0.00042 20.6 0.2 0.14 12.4 0.0 3.5 2 1 0 3 3 3 1 AAA domain AAA_33 PF13671.1 CBZ09045.1 - 0.00064 19.6 0.0 0.00064 19.6 0.0 3.8 4 0 0 4 4 4 1 AAA domain DUF3508 PF12018.3 CBZ09045.1 - 0.0036 16.3 0.4 1.7 7.5 0.0 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF3508) AAA PF00004.24 CBZ09045.1 - 0.0042 17.2 0.0 0.14 12.3 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ADK PF00406.17 CBZ09045.1 - 0.017 14.9 0.0 0.075 12.9 0.0 2.1 2 0 0 2 2 2 0 Adenylate kinase AAA_5 PF07728.9 CBZ09045.1 - 0.025 14.3 0.0 0.48 10.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 CBZ09045.1 - 0.47 10.6 0.0 7.6 6.7 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Adeno_hexon PF01065.14 CBZ09045.1 - 0.57 8.9 0.1 1.5 7.6 0.0 1.6 2 0 0 2 2 2 0 Hexon, adenovirus major coat protein, N-terminal domain ATP_bind_3 PF01171.15 CBZ09046.1 - 1.5e-17 63.7 0.0 2.5e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.11 CBZ09046.1 - 0.04 12.4 0.0 0.086 11.3 0.0 1.5 1 1 0 1 1 1 0 tRNA methyl transferase PAPS_reduct PF01507.14 CBZ09046.1 - 0.13 12.0 0.0 0.19 11.5 0.0 1.3 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Sugar_tr PF00083.19 CBZ09047.1 - 4.8e-84 282.5 29.7 4.6e-83 279.2 20.6 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBZ09047.1 - 3.6e-10 39.0 48.2 1.2e-08 34.0 15.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily NfeD PF01957.13 CBZ09047.1 - 2.1 8.5 0.0 2.1 8.5 0.0 3.6 3 2 0 3 3 3 0 NfeD-like C-terminal, partner-binding PHO4 PF01384.15 CBZ09047.1 - 3.9 6.0 10.8 4.4 5.8 0.5 2.9 2 1 0 3 3 3 0 Phosphate transporter family ACBP PF00887.14 CBZ09048.1 - 2.1e-16 59.3 0.1 3.8e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein Tmemb_185A PF10269.4 CBZ09050.1 - 0.0075 15.9 0.0 0.0089 15.6 0.0 1.1 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein NYD-SP28_assoc PF14775.1 CBZ09051.1 - 2.5e-21 75.1 2.2 2.5e-21 75.1 1.5 3.1 3 0 0 3 3 3 1 Sperm tail C-terminal domain NYD-SP28 PF14772.1 CBZ09051.1 - 9.9e-18 64.1 4.6 9.9e-18 64.1 3.2 5.5 5 2 1 6 6 6 2 Sperm tail Ovate PF04844.8 CBZ09051.1 - 0.00057 19.6 0.7 1.7 8.5 0.0 3.8 3 1 1 4 4 4 2 Transcriptional repressor, ovate FliD_C PF07195.7 CBZ09051.1 - 0.24 10.6 20.7 0.068 12.4 2.6 3.6 3 1 0 3 3 3 0 Flagellar hook-associated protein 2 C-terminus Mito_carr PF00153.22 CBZ09053.1 - 4.9e-33 112.7 3.9 9.8e-13 47.6 0.0 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein KASH PF10541.4 CBZ09054.1 - 0.19 11.6 0.1 0.19 11.6 0.1 3.8 4 1 0 4 4 4 0 Nuclear envelope localisation domain Pneumo_matrix PF03393.11 CBZ09056.1 - 0.12 11.2 0.0 0.25 10.2 0.0 1.6 1 1 0 2 2 2 0 Pneumovirus matrix protein CSD PF00313.17 CBZ09056.1 - 0.13 12.1 0.0 0.41 10.4 0.0 1.8 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain Metalloenzyme PF01676.13 CBZ09057.1 - 1.9e-69 233.8 0.0 2.2e-69 233.6 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 CBZ09057.1 - 4e-63 212.7 0.0 5.4e-63 212.3 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 CBZ09057.1 - 1e-07 31.6 0.0 1.8e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 CBZ09057.1 - 0.14 11.3 0.1 1.3 8.1 0.0 2.5 2 1 0 2 2 2 0 Sulfatase FtsJ PF01728.14 CBZ09058.1 - 2.7e-28 99.1 0.0 4.7e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Cyt-b5 PF00173.23 CBZ09059.1 - 2.9e-11 43.0 0.0 3.9e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Spc7 PF08317.6 CBZ09060.1 - 0.0061 15.2 3.6 0.0061 15.2 2.5 1.8 1 1 0 1 1 1 1 Spc7 kinetochore protein bZIP_2 PF07716.10 CBZ09060.1 - 0.036 13.8 3.1 0.036 13.8 2.2 3.4 3 1 0 3 3 3 0 Basic region leucine zipper DUF972 PF06156.8 CBZ09060.1 - 0.063 13.6 13.2 1.6 9.1 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Val_tRNA-synt_C PF10458.4 CBZ09060.1 - 0.1 12.7 0.1 0.1 12.7 0.1 3.7 3 1 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm GAS PF13851.1 CBZ09060.1 - 0.16 11.1 14.9 0.22 10.7 10.3 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4239 PF14023.1 CBZ09060.1 - 0.24 10.7 3.9 0.31 10.3 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) DUF812 PF05667.6 CBZ09060.1 - 0.26 9.7 15.8 0.036 12.5 1.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF812) TPR_MLP1_2 PF07926.7 CBZ09060.1 - 0.31 10.7 17.3 0.18 11.5 0.6 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Fzo_mitofusin PF04799.8 CBZ09060.1 - 0.52 9.6 10.0 0.93 8.8 3.6 2.1 1 1 1 2 2 2 0 fzo-like conserved region Ax_dynein_light PF10211.4 CBZ09060.1 - 0.62 9.8 15.7 1.6 8.5 0.9 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain V_ATPase_I PF01496.14 CBZ09060.1 - 1.5 6.5 6.0 1.7 6.4 4.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GrpE PF01025.14 CBZ09060.1 - 6.4 6.2 15.0 0.23 10.9 0.3 2.3 1 1 1 2 2 2 0 GrpE ACCA PF03255.9 CBZ09060.1 - 6.7 6.2 7.9 3.5 7.1 0.9 2.2 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Solute_trans_a PF03619.11 CBZ09061.1 - 3e-86 289.1 16.2 4e-86 288.7 11.2 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha WBS28 PF15164.1 CBZ09061.1 - 0.65 9.0 0.0 0.65 9.0 0.0 2.7 3 0 0 3 3 3 0 Williams-Beuren syndrome chromosomal region 28 protein homologue AAA_16 PF13191.1 CBZ09062.1 - 3.6e-08 33.6 2.7 4e-05 23.6 0.1 3.2 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 CBZ09062.1 - 2.2e-06 27.8 0.0 5.9e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBZ09062.1 - 0.0029 17.3 2.2 0.084 12.6 0.0 2.7 2 1 0 2 2 2 1 Part of AAA domain AAA_28 PF13521.1 CBZ09062.1 - 0.0092 15.9 0.1 0.11 12.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain DNA_primase_S PF01896.14 CBZ09062.1 - 0.022 14.5 0.0 0.2 11.4 0.0 2.2 1 1 1 2 2 2 0 Eukaryotic and archaeal DNA primase small subunit NACHT PF05729.7 CBZ09062.1 - 0.029 14.0 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.1 CBZ09062.1 - 0.057 13.2 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 CBZ09062.1 - 0.19 11.4 0.0 0.42 10.3 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 CBZ09062.1 - 0.25 12.1 1.9 0.77 10.5 0.5 2.6 2 1 0 2 2 2 0 AAA domain Rep_fac_C PF08542.6 CBZ09063.1 - 2.2e-19 69.2 0.0 4.4e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 CBZ09063.1 - 5.5e-15 55.3 0.0 8.1e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 CBZ09063.1 - 1.7e-07 31.4 0.0 6.2e-07 29.6 0.0 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 CBZ09063.1 - 0.0011 19.0 0.0 0.53 10.3 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.9 CBZ09063.1 - 0.0023 17.6 0.1 0.021 14.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CBZ09063.1 - 0.0039 16.3 0.0 0.1 11.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 CBZ09063.1 - 0.0093 16.1 0.0 0.034 14.2 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.1 CBZ09063.1 - 0.0097 15.5 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBZ09063.1 - 0.0097 15.9 0.2 0.46 10.4 0.0 2.9 2 2 1 3 3 3 1 AAA ATPase domain Rad17 PF03215.10 CBZ09063.1 - 0.02 13.5 0.0 0.024 13.3 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 CBZ09063.1 - 0.034 13.5 0.0 0.073 12.5 0.0 1.4 1 1 0 1 1 1 0 AAA-like domain RuvB_N PF05496.7 CBZ09063.1 - 0.041 12.9 0.0 0.49 9.4 0.0 2.5 2 1 1 3 3 3 0 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 CBZ09063.1 - 0.058 12.8 0.0 5.5 6.4 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain BBIP10 PF14777.1 CBZ09063.1 - 0.06 12.7 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Cilia BBSome complex subunit 10 Mito_carr PF00153.22 CBZ09064.1 - 1.6e-26 91.8 1.7 1.7e-13 50.0 0.2 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein AAA_17 PF13207.1 CBZ09065.1 - 0.14 12.9 0.0 0.59 10.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain ORC4_C PF14629.1 CBZ09066.1 - 0.028 13.8 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus Ribosomal_L1 PF00687.16 CBZ09068.1 - 1.1e-21 77.1 0.0 1.3e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF3633 PF12315.3 CBZ09068.1 - 0.046 13.0 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3633) FA_desaturase PF00487.19 CBZ09069.1 - 3.5e-33 115.1 11.6 5.3e-33 114.5 8.0 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 CBZ09069.1 - 6.7e-11 41.8 0.0 1.6e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain 2-oxoacid_dh PF00198.18 CBZ09073.1 - 1.1e-78 263.7 0.1 1.4e-78 263.3 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CBZ09073.1 - 5.4e-17 61.2 0.8 1.6e-16 59.7 0.3 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 CBZ09073.1 - 4.3e-15 55.0 0.1 8.4e-15 54.1 0.1 1.5 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 CBZ09073.1 - 0.012 15.2 0.4 3 7.5 0.1 2.7 2 0 0 2 2 2 0 Biotin-lipoyl like LRR_1 PF00560.28 CBZ09075.1 - 0.00015 21.2 0.5 1.9 8.8 0.0 4.7 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_4 PF12799.2 CBZ09075.1 - 0.0017 17.9 0.0 0.28 10.8 0.0 3.3 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) Chlorovi_GP_rpt PF06598.6 CBZ09075.1 - 0.012 15.3 1.7 2.8 7.8 0.0 3.3 3 0 0 3 3 3 0 Chlorovirus glycoprotein repeat ESSS PF10183.4 CBZ39904.1 - 1.2e-13 51.3 5.6 1.4e-13 51.1 3.9 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Proteasome PF00227.21 CBZ39905.1 - 1.1e-30 106.3 0.0 1.3e-30 106.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit CDP-OH_P_transf PF01066.16 CBZ39906.1 - 1.5e-20 73.3 0.1 5.6e-20 71.5 0.1 1.9 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Amastin PF07344.6 CBZ39907.1 - 6.1e-56 188.3 9.0 7.2e-56 188.1 6.3 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ39907.1 - 0.35 10.5 16.7 0.025 14.2 7.8 1.9 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF1469 PF07332.6 CBZ39907.1 - 4 7.1 13.7 0.045 13.4 2.6 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) Amastin PF07344.6 CBZ39908.1 - 2.2e-55 186.5 10.6 2.5e-55 186.3 7.4 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ39908.1 - 7e-05 22.5 9.2 7e-05 22.5 6.4 1.9 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF1467 PF07330.7 CBZ39908.1 - 0.036 13.8 3.9 1 9.1 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1467) Clc-like PF07062.7 CBZ39908.1 - 4 6.6 10.2 0.23 10.6 3.2 1.6 2 0 0 2 2 2 0 Clc-like AAA PF00004.24 CBZ39910.1 - 0.00034 20.7 0.0 0.0024 18.0 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF3138 PF11336.3 CBZ39912.1 - 1.2 7.2 3.7 1.7 6.7 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) FeoB_N PF02421.13 CBZ39913.1 - 0.0026 17.0 64.3 2 7.6 1.5 8.3 1 1 9 11 11 11 11 Ferrous iron transport protein B ATP-synt_ab PF00006.20 CBZ39914.1 - 2.2e-44 151.5 0.2 3.6e-43 147.5 0.0 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CBZ39914.1 - 3.1e-22 79.1 0.3 4.9e-22 78.5 0.2 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain Amastin PF07344.6 CBZ39917.1 - 1.4e-50 170.9 15.6 1.6e-50 170.7 10.8 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF1467 PF07330.7 CBZ39917.1 - 0.08 12.7 0.0 0.08 12.7 0.0 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1467) Claudin_2 PF13903.1 CBZ39917.1 - 6.7 6.3 21.0 0.18 11.4 9.4 1.9 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction