# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- EF-hand_8 PF13833.6 CAM36430.1 - 0.023 14.6 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 CAM36430.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 EF hand Asp_protease PF09668.10 CAM36431.1 - 5e-58 194.3 0.5 7.6e-58 193.7 0.5 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CAM36431.1 - 3e-18 66.1 0.0 8.6e-18 64.7 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CAM36431.1 - 4.1e-08 33.7 0.0 1.4e-07 32.0 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease UBA_4 PF14555.6 CAM36431.1 - 2.1e-05 24.2 0.3 4e-05 23.3 0.3 1.5 1 0 0 1 1 1 1 UBA-like domain RVP_2 PF08284.11 CAM36431.1 - 0.00015 21.6 0.0 0.00027 20.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 CAM36431.1 - 0.012 15.9 0.0 0.048 14.0 0.0 2.0 1 1 1 2 2 2 0 Retroviral aspartyl protease DUF2946 PF11162.8 CAM36432.1 - 1.5e-17 64.3 1.3 3.3e-17 63.2 1.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2946) Shisa PF13908.6 CAM36432.1 - 0.0037 17.5 0.0 0.01 16.1 0.0 1.7 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator Orthoreo_P10 PF07204.11 CAM36432.1 - 0.015 15.3 0.2 0.044 13.8 0.2 1.8 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 MAP17 PF15807.5 CAM36432.1 - 0.019 15.2 0.0 0.035 14.3 0.0 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Hum_adeno_E3A PF05393.11 CAM36432.1 - 0.035 14.1 0.5 0.096 12.7 0.5 1.7 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein FAM176 PF14851.6 CAM36432.1 - 0.16 11.6 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 FAM176 family EphA2_TM PF14575.6 CAM36432.1 - 0.18 12.7 0.0 0.81 10.6 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Tweety PF04906.13 CAM36432.1 - 0.83 8.2 4.9 0.74 8.4 0.6 2.0 2 0 0 2 2 2 0 Tweety Exo_endo_phos PF03372.23 CAM36433.1 - 1.4e-06 28.0 0.0 4.1e-06 26.5 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TPR_21 PF09976.9 CAM36433.1 - 0.11 12.2 3.8 0.035 13.8 1.0 1.5 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain Kinesin PF00225.23 CAM36434.1 - 1e-93 313.9 0.0 1.4e-93 313.5 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CAM36434.1 - 5.9e-15 55.5 0.0 1.2e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding SAM_1 PF00536.30 CAM36434.1 - 0.055 13.9 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Arg_decarbox_C PF17944.1 CAM36434.1 - 0.079 13.5 2.0 0.26 11.9 0.6 2.4 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension BLOC1_2 PF10046.9 CAM36434.1 - 0.15 12.4 1.4 0.37 11.1 1.4 1.7 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GYF PF02213.16 CAM36435.1 - 0.0015 18.1 0.1 0.0026 17.4 0.1 1.3 1 0 0 1 1 1 1 GYF domain CPSase_L_D2 PF02786.17 CAM36436.1 - 1.3e-77 260.0 0.5 2.9e-77 258.9 0.5 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CAM36436.1 - 1.2e-43 148.1 0.4 3.7e-43 146.6 0.1 2.0 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CAM36436.1 - 6e-36 122.8 0.0 1.8e-35 121.3 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CAM36436.1 - 6.2e-14 51.6 4.1 6.2e-14 51.6 4.1 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme PCC_BT PF18140.1 CAM36436.1 - 1.7e-09 38.1 0.1 4.5e-09 36.7 0.1 1.6 1 0 0 1 1 1 1 Propionyl-coenzyme A carboxylase BT domain ATP-grasp PF02222.22 CAM36436.1 - 1.2e-08 34.7 1.0 3.1e-08 33.4 0.3 2.0 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 CAM36436.1 - 2.6e-06 27.1 0.3 6e-06 25.9 0.3 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 CAM36436.1 - 0.00033 20.7 0.1 0.00059 19.9 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 CAM36436.1 - 0.002 17.9 0.0 0.0048 16.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Biotin_lipoyl_2 PF13533.6 CAM36436.1 - 0.0028 17.4 0.8 0.013 15.3 0.1 2.4 2 1 1 3 3 3 1 Biotin-lipoyl like ATPgrasp_ST PF14397.6 CAM36436.1 - 0.0076 15.5 0.0 0.024 13.9 0.0 1.8 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp HlyD_D23 PF16576.5 CAM36436.1 - 0.023 13.9 1.0 0.22 10.7 0.2 2.2 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 CAM36436.1 - 0.029 15.1 0.7 0.15 12.7 0.3 2.4 1 1 1 2 2 2 0 HlyD family secretion protein GCV_H PF01597.19 CAM36436.1 - 0.089 12.7 0.8 0.22 11.4 0.8 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein RNA_pol_inhib PF16857.5 CAM36436.1 - 0.17 11.7 0.6 1.3 8.8 0.0 2.7 3 0 0 3 3 3 0 RNA polymerase inhibitor PLC-beta_C PF08703.10 CAM36437.1 - 0.014 15.4 4.6 0.014 15.4 4.6 1.4 2 0 0 2 2 2 0 PLC-beta C terminal DUF3138 PF11336.8 CAM36437.1 - 0.19 10.3 3.6 0.27 9.8 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Peptidase_M16 PF00675.20 CAM36437.1 - 0.26 11.3 2.3 0.32 11.0 0.9 1.8 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) Tox-ODYAM1 PF15642.6 CAM36437.1 - 0.27 10.1 4.2 0.37 9.7 4.2 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus DltD PF04914.12 CAM36437.1 - 0.88 8.9 3.4 1.1 8.5 3.4 1.1 1 0 0 1 1 1 0 DltD protein Atg14 PF10186.9 CAM36437.1 - 1.4 8.0 7.7 1.6 7.7 7.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 BSD PF03909.17 CAM36438.1 - 1.7e-07 31.1 0.0 3.2e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 BSD domain Thymidylate_kin PF02223.17 CAM36440.1 - 1.8e-32 112.5 0.0 2.2e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.6 CAM36440.1 - 1.5e-05 25.2 0.1 5.5e-05 23.4 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 CAM36440.1 - 4.3e-05 24.1 0.0 0.00016 22.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CAM36440.1 - 0.0049 17.3 0.1 0.011 16.2 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain Vps39_2 PF10367.9 CAM36440.1 - 0.0082 16.6 0.1 0.43 11.0 0.0 3.1 3 2 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 TsaE PF02367.17 CAM36440.1 - 0.01 15.8 0.0 0.037 14.0 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 CAM36440.1 - 0.013 16.0 0.0 0.037 14.4 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CAM36440.1 - 0.014 15.7 0.4 0.024 14.9 0.4 1.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CAM36440.1 - 0.024 14.9 0.0 0.056 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.18 CAM36440.1 - 0.03 13.6 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_30 PF13604.6 CAM36440.1 - 0.051 13.3 0.2 0.19 11.4 0.0 2.1 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 CAM36440.1 - 0.058 12.6 0.0 0.13 11.5 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF853 PF05872.12 CAM36440.1 - 0.065 11.8 0.0 0.099 11.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA_19 PF13245.6 CAM36440.1 - 0.07 13.5 0.1 0.13 12.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain Glyco_transf_28 PF03033.20 CAM36440.1 - 0.092 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Glyco_transf_11 PF01531.16 CAM36441.1 - 7.2e-11 41.8 0.1 5.2e-08 32.5 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 11 Glutaredoxin PF00462.24 CAM36442.1 - 9.6e-18 64.2 0.3 1.7e-17 63.4 0.1 1.5 2 0 0 2 2 2 1 Glutaredoxin ATG16 PF08614.11 CAM36443.2 - 0.7 10.1 3.1 1.6 8.9 0.1 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Par3_HAL_N_term PF12053.8 CAM36445.1 - 0.038 14.2 0.0 0.064 13.5 0.0 1.4 1 1 0 1 1 1 0 N-terminal of Par3 and HAL proteins LSM PF01423.22 CAM36447.1 - 2.8e-10 39.7 0.0 3.2e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain Voltage_CLC PF00654.20 CAM36449.1 - 3.3e-90 302.9 31.8 3.7e-89 299.4 29.4 2.0 2 0 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 CAM36449.1 - 0.0002 21.7 0.0 0.07 13.6 0.0 2.6 2 0 0 2 2 2 2 CBS domain LMWPc PF01451.21 CAM36451.2 - 1.5e-05 25.4 0.0 2.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase CUE PF02845.16 CAM36452.1 - 2.5e-15 55.8 0.1 1.1e-06 28.2 0.0 4.0 4 0 0 4 4 4 3 CUE domain Smr PF01713.21 CAM36452.1 - 2.4e-10 40.6 0.7 7e-10 39.1 0.7 1.9 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.10 CAM36452.1 - 1.3e-08 35.1 0.1 6e-08 33.0 0.1 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) UBA PF00627.31 CAM36452.1 - 9.4e-06 25.4 0.0 0.041 13.8 0.0 2.9 2 0 0 2 2 2 2 UBA/TS-N domain DMA PF03474.14 CAM36452.1 - 0.012 15.2 0.0 6.5 6.4 0.0 2.6 2 0 0 2 2 2 0 DMRTA motif HOIP-UBA PF16678.5 CAM36452.1 - 0.06 13.4 1.3 18 5.3 0.1 3.3 3 0 0 3 3 3 0 HOIP UBA domain pair zf_CCCH_4 PF18345.1 CAM36452.1 - 0.46 10.6 30.3 0.26 11.4 0.2 4.9 4 1 0 4 4 4 0 Zinc finger domain Pro_isomerase PF00160.21 CAM36453.2 - 3.5e-37 128.1 0.0 4.9e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD AMP-binding PF00501.28 CAM36454.1 - 2.6e-11 42.8 0.0 3.8e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme SUIM_assoc PF16619.5 CAM36454.1 - 0.38 10.8 6.7 19 5.4 0.2 3.4 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 SNF2_N PF00176.23 CAM36456.2 - 6.4e-39 133.6 0.0 1.1e-38 132.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CAM36456.2 - 1.2e-14 54.6 0.0 2.7e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CAM36456.2 - 7.7e-06 25.8 0.0 1.4e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CAM36456.2 - 0.0003 20.9 0.0 0.0012 18.9 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 CAM36456.2 - 0.1 12.2 0.1 0.35 10.5 0.1 1.9 1 1 0 1 1 1 0 SWI2/SNF2 ATPase Beta_helix PF13229.6 CAM36457.1 - 7e-11 42.2 0.1 1.2e-10 41.4 0.1 1.3 1 0 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 CAM36457.1 - 1.8e-06 27.4 0.1 2.8e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Thioredoxin PF00085.20 CAM36458.1 - 2.1e-20 72.6 0.1 2.5e-20 72.4 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CAM36458.1 - 0.00059 20.1 0.2 0.024 14.9 0.1 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 CAM36458.1 - 0.0006 20.2 0.3 0.0029 18.0 0.3 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 CAM36458.1 - 0.0045 16.4 0.0 0.0048 16.3 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 CAM36458.1 - 0.0077 16.1 0.0 0.0087 16.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_6 PF13848.6 CAM36458.1 - 0.037 13.9 0.0 0.043 13.7 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain Phosducin PF02114.16 CAM36458.1 - 0.039 12.9 0.0 0.042 12.8 0.0 1.1 1 0 0 1 1 1 0 Phosducin HyaE PF07449.11 CAM36458.1 - 0.059 13.3 0.0 0.089 12.8 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.6 CAM36458.1 - 0.06 13.5 0.3 0.095 12.9 0.3 1.5 1 1 0 1 1 1 0 Thioredoxin-like PseudoU_synth_2 PF00849.22 CAM36459.1 - 4.1e-22 79.0 0.0 1.4e-21 77.2 0.0 1.8 2 0 0 2 2 2 1 RNA pseudouridylate synthase Cmc1 PF08583.10 CAM36460.1 - 4.3e-06 26.7 3.3 7.1e-06 25.9 3.3 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 CAM36460.1 - 0.0036 17.3 4.5 0.0076 16.2 4.5 1.5 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 CAM36460.1 - 0.049 13.8 3.2 1.7 8.9 3.2 2.4 1 1 1 2 2 2 0 CHCH domain COX17 PF05051.13 CAM36460.1 - 0.09 13.1 2.0 0.095 13.1 0.2 1.9 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) UCR_hinge PF02320.16 CAM36460.1 - 0.46 10.7 5.7 1.9 8.8 0.5 2.5 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein 4F5 PF04419.14 CAM36461.1 - 3.7e-13 50.1 7.2 3.7e-13 50.1 7.2 2.0 2 0 0 2 2 2 1 4F5 protein family DHHA2 PF02833.14 CAM36462.1 - 1.8e-22 80.1 0.0 5.8e-22 78.4 0.0 1.7 2 0 0 2 2 2 1 DHHA2 domain DHH PF01368.20 CAM36462.1 - 1.9e-08 34.5 0.0 3.2e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 DHH family Thoc2 PF11732.8 CAM36462.1 - 0.083 13.0 0.1 0.41 10.7 0.0 2.2 2 1 0 2 2 2 0 Transcription- and export-related complex subunit Dor1 PF04124.12 CAM36463.1 - 0.1 11.2 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Dor1-like family WD40 PF00400.32 CAM36464.1 - 0.001 19.9 2.6 0.034 15.0 0.2 3.1 3 0 0 3 3 3 1 WD domain, G-beta repeat PQQ_2 PF13360.6 CAM36464.1 - 0.056 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 PQQ-like domain ANAPC4_WD40 PF12894.7 CAM36464.1 - 0.15 12.4 0.0 19 5.7 0.0 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Urate_ox_N PF06181.11 CAM36465.1 - 0.082 12.2 0.1 0.1 11.9 0.1 1.1 1 0 0 1 1 1 0 Urate oxidase N-terminal MPC PF03650.13 CAM36466.1 - 1.1e-16 60.9 0.6 1.3e-16 60.7 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Rpn3_C PF08375.11 CAM36468.1 - 0.022 15.2 1.6 0.053 13.9 1.6 1.6 1 0 0 1 1 1 0 Proteasome regulatory subunit C-terminal Aldedh PF00171.22 CAM36468.1 - 0.092 11.2 2.2 0.15 10.6 2.2 1.2 1 0 0 1 1 1 0 Aldehyde dehydrogenase family ApoLp-III PF07464.11 CAM36468.1 - 0.16 12.1 1.6 0.32 11.1 1.6 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) FlgN PF05130.12 CAM36468.1 - 1.3 9.5 12.6 1.4 9.4 4.1 2.7 2 1 1 3 3 3 0 FlgN protein TACC_C PF05010.14 CAM36468.1 - 1.4 8.6 10.1 2.5 7.9 10.1 1.3 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal NEMO PF11577.8 CAM36468.1 - 1.4 8.9 7.5 0.38 10.8 3.7 2.0 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO DUF1451 PF07295.11 CAM36468.1 - 1.7 8.7 8.6 1.1 9.3 3.2 2.3 1 1 1 2 2 2 0 Zinc-ribbon containing domain TMEM208_SND2 PF05620.11 CAM36470.1 - 1.2e-34 119.5 0.0 1.5e-34 119.2 0.0 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Dymeclin PF09742.9 CAM36471.1 - 2.9e-48 164.8 0.0 3.4e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 CAM36471.1 - 0.92 7.6 3.9 11 3.9 0.1 2.7 3 0 0 3 3 3 0 High-temperature-induced dauer-formation protein FSA_C PF10479.9 CAM36471.1 - 1.4 6.9 4.7 0.18 9.9 0.3 1.6 2 0 0 2 2 2 0 Fragile site-associated protein C-terminus Dehydrin PF00257.19 CAM36472.1 - 0.041 14.4 0.6 0.041 14.4 0.6 2.1 3 0 0 3 3 3 0 Dehydrin DUF1664 PF07889.12 CAM36472.1 - 0.33 11.0 3.2 0.3 11.1 0.5 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) IMUP PF15761.5 CAM36472.1 - 6 7.6 9.9 11 6.7 6.6 2.6 2 0 0 2 2 2 0 Immortalisation up-regulated protein Ribosomal_S7e PF01251.18 CAM36474.1 - 5.2e-63 212.1 3.0 6.4e-63 211.8 3.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S7e Ribosomal_S7e PF01251.18 CAM36475.1 - 2.9e-63 213.0 3.0 3.3e-63 212.8 3.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e zf-UBP PF02148.19 CAM36476.1 - 1.1e-10 41.6 8.6 1.1e-10 41.6 8.6 2.5 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 CAM36476.1 - 3.4e-08 33.7 7.9 3.4e-08 33.7 7.9 3.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CAM36476.1 - 2.5e-06 27.2 9.6 2.5e-06 27.2 9.6 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CAM36476.1 - 0.00013 21.7 16.3 0.0014 18.4 3.6 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CAM36476.1 - 0.00031 21.0 4.6 0.00031 21.0 4.6 2.6 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CAM36476.1 - 0.0017 18.3 6.7 0.0017 18.3 6.7 3.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CAM36476.1 - 0.0042 16.9 8.4 0.0042 16.9 8.4 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CAM36476.1 - 0.0067 16.2 5.5 0.0067 16.2 5.5 3.0 4 0 0 4 4 4 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CAM36476.1 - 0.018 15.1 5.8 0.018 15.1 5.8 2.9 1 1 1 2 2 2 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 CAM36476.1 - 0.034 14.2 3.8 0.11 12.5 3.8 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger MeaB PF03308.16 CAM36476.1 - 0.046 12.7 1.1 0.097 11.6 1.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Seryl_tRNA_N PF02403.22 CAM36476.1 - 0.15 12.3 6.3 0.31 11.3 6.3 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain RecR PF02132.15 CAM36476.1 - 0.19 11.3 10.5 0.13 11.8 0.7 3.2 3 0 0 3 3 3 0 RecR protein zf-C3HC4_4 PF15227.6 CAM36476.1 - 0.88 9.8 21.5 2.2 8.5 11.5 2.6 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Caskin-Pro-rich PF16907.5 CAM36476.1 - 7.9 7.1 10.3 1.6 9.3 4.0 3.0 3 1 0 3 3 2 0 Proline rich region of Caskin proteins Zn_ribbon_17 PF17120.5 CAM36476.1 - 9.6 5.9 16.5 0.74 9.5 3.9 2.8 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type MFS_5 PF05631.14 CAM36477.1 - 1.7e-10 40.4 3.9 7.8e-06 25.0 0.5 2.4 2 0 0 2 2 2 2 Sugar-tranasporters, 12 TM Isochorismatase PF00857.20 CAM36478.1 - 3.9e-23 82.5 0.0 4.7e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family AAA_16 PF13191.6 CAM36479.1 - 2.2e-05 24.9 0.9 5.4e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 CAM36479.1 - 2.6e-05 24.8 0.0 6.2e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CAM36479.1 - 0.0031 17.9 0.0 0.0061 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Paired_CXXCH_1 PF09699.10 CAM36479.1 - 0.013 15.2 1.3 0.046 13.5 1.3 1.9 1 0 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) AAA_28 PF13521.6 CAM36479.1 - 0.027 14.7 0.0 0.057 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 CAM36479.1 - 0.041 14.3 0.0 0.08 13.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 CAM36479.1 - 0.15 11.2 0.0 0.32 10.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain KTI12 PF08433.10 CAM36479.1 - 0.21 11.0 0.0 0.42 10.0 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AMP-binding PF00501.28 CAM36480.1 - 3.1e-87 292.9 0.1 4.1e-87 292.5 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 CAM36482.1 - 7.1e-94 314.8 0.0 9.5e-94 314.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 CAM36483.1 - 5.4e-95 318.5 0.0 7.2e-95 318.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 CAM36484.1 - 1.3e-35 122.8 0.0 1.9e-28 99.2 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme ARA70 PF12489.8 CAM36484.1 - 0.0059 16.8 0.1 0.011 15.9 0.1 1.4 1 0 0 1 1 1 1 Nuclear coactivator zf-CCHC_3 PF13917.6 CAM36486.1 - 0.0001 22.2 21.0 0.0057 16.6 0.4 3.8 4 0 0 4 4 4 2 Zinc knuckle FOXP-CC PF16159.5 CAM36486.1 - 0.92 10.2 4.2 26 5.5 0.5 2.8 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-CCHC PF00098.23 CAM36486.1 - 2 8.6 31.7 0.21 11.7 2.4 3.5 3 0 0 3 3 3 0 Zinc knuckle DUF5637 PF18687.1 CAM36486.1 - 2.9 7.9 13.9 1.8 8.6 0.7 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5637) PRP3 PF08572.10 CAM36487.1 - 2.7e-13 50.2 0.9 1.5e-12 47.7 0.9 2.0 1 1 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 CAM36487.1 - 4.2e-12 46.4 0.0 1e-11 45.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) Rrn6 PF10214.9 CAM36487.1 - 0.3 9.5 2.8 0.58 8.6 2.8 1.4 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Mtc PF03820.17 CAM36488.1 - 4.6e-83 278.8 0.8 5.1e-83 278.7 0.8 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier RNA_ligase PF09414.10 CAM36490.1 - 7.1e-21 75.2 0.0 1e-20 74.7 0.0 1.3 1 0 0 1 1 1 1 RNA ligase T4_Rnl2_C PF18043.1 CAM36490.1 - 6.5e-07 29.4 0.1 1.3e-06 28.5 0.1 1.4 1 0 0 1 1 1 1 T4 RNA ligase 2 C-terminal RabGAP-TBC PF00566.18 CAM36491.1 - 2.2e-24 86.3 0.0 2.1e-11 43.9 0.3 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain PLAC8 PF04749.17 CAM36495.1 - 6.6e-14 52.7 8.9 9.9e-14 52.2 8.9 1.3 1 0 0 1 1 1 1 PLAC8 family Olduvai PF06758.13 CAM36495.1 - 0.016 15.5 0.1 0.016 15.5 0.1 2.2 2 0 0 2 2 2 0 Olduvai domain PLAC8 PF04749.17 CAM36496.1 - 1.8e-12 48.1 8.7 1.8e-12 48.1 8.7 2.2 2 0 0 2 2 2 1 PLAC8 family Acyl_transf_3 PF01757.22 CAM36496.1 - 0.15 11.1 1.1 1.3 8.0 0.1 2.0 1 1 1 2 2 2 0 Acyltransferase family ThiF PF00899.21 CAM36497.1 - 6e-76 255.0 0.0 1.5e-75 253.8 0.0 1.6 1 1 0 1 1 1 1 ThiF family DASH_Spc19 PF08287.11 CAM36499.1 - 0.63 9.9 3.5 1.2 9.0 3.5 1.4 1 0 0 1 1 1 0 Spc19 DEAD PF00270.29 CAM36502.1 - 2e-42 144.9 0.1 5.6e-42 143.5 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAM36502.1 - 5.5e-29 100.7 0.3 3.2e-28 98.3 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 CAM36502.1 - 5.5e-05 22.6 0.2 0.00017 21.0 0.0 1.8 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 CAM36502.1 - 0.065 13.5 0.7 0.33 11.2 0.7 2.3 1 1 0 1 1 1 0 AAA domain DGF-1_C PF11040.8 CAM36503.1 - 1.5 8.9 5.3 3.6 7.7 1.7 3.1 1 1 1 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus zf-C2H2 PF00096.26 CAM36504.1 - 0.0082 16.6 3.3 0.027 14.9 3.3 2.0 1 0 0 1 1 1 1 Zinc finger, C2H2 type CpXC PF14353.6 CAM36504.1 - 0.061 13.4 0.2 0.099 12.7 0.2 1.3 1 0 0 1 1 1 0 CpXC protein zf-C2H2_4 PF13894.6 CAM36504.1 - 0.091 13.7 3.0 0.23 12.4 3.0 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger FYDLN_acid PF09538.10 CAM36504.1 - 0.21 12.3 1.8 0.46 11.2 1.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) BK_channel_a PF03493.18 CAM36505.1 - 3.9e-12 46.2 0.0 1.1e-11 44.8 0.0 1.7 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 CAM36505.1 - 1.4e-10 40.9 4.6 5.9e-10 39.0 4.6 2.1 1 0 0 1 1 1 1 Ion channel DUF962 PF06127.11 CAM36505.1 - 1.1 9.4 4.0 3.6 7.7 4.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF962) HSP70 PF00012.20 CAM36507.2 - 2.2e-27 95.5 1.8 7.1e-24 83.9 0.1 4.0 3 1 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 CAM36507.2 - 0.014 14.2 0.6 0.027 13.3 0.6 1.4 1 0 0 1 1 1 0 MreB/Mbl protein DUF4995 PF16386.5 CAM36508.2 - 0.053 13.5 0.5 0.15 12.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function Inhibitor_I67 PF11405.8 CAM36508.2 - 5.5 7.3 7.2 3.2 8.1 1.1 2.7 3 0 0 3 3 3 0 Bromelain inhibitor VI CNOT11 PF10155.9 CAM36509.2 - 0.00026 21.1 0.2 0.0011 19.1 0.0 2.0 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 11 DUF445 PF04286.12 CAM36509.2 - 0.0026 17.6 2.0 0.0027 17.6 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF445) UTP15_C PF09384.10 CAM36511.1 - 3.6e-31 107.8 0.2 5.6e-31 107.2 0.2 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 CAM36511.1 - 1e-13 51.5 1.8 0.012 16.4 0.1 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat P34-Arc PF04045.14 CAM36511.1 - 0.047 13.4 0.6 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 Arp2/3 complex, 34 kD subunit p34-Arc AhpC-TSA PF00578.21 CAM36512.1 - 1.9e-38 131.2 0.0 2.5e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CAM36512.1 - 7.2e-17 61.5 0.0 9e-17 61.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CAM36512.1 - 3.5e-08 33.2 0.1 6.9e-08 32.2 0.1 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 CAM36512.1 - 0.023 14.6 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 SCO1/SenC EIAV_GP90 PF00971.18 CAM36512.1 - 0.054 12.2 0.1 0.068 11.8 0.1 1.1 1 0 0 1 1 1 0 EIAV coat protein, gp90 Pro_isomerase PF00160.21 CAM36513.1 - 2.2e-45 154.8 0.0 3.9e-45 154.0 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Arginase PF00491.21 CAM36515.1 - 9.2e-27 94.3 0.0 1.5e-26 93.6 0.0 1.3 1 1 0 1 1 1 1 Arginase family Tropomyosin_1 PF12718.7 CAM36516.1 - 3.6e-05 24.0 3.4 3.6e-05 24.0 3.4 3.5 1 1 1 3 3 3 1 Tropomyosin like Lebercilin PF15619.6 CAM36516.1 - 0.002 17.8 23.3 0.002 17.8 23.3 4.0 3 2 0 3 3 3 2 Ciliary protein causing Leber congenital amaurosis disease DUF1664 PF07889.12 CAM36516.1 - 0.86 9.7 23.4 0.044 13.8 5.9 4.0 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 CAM36516.1 - 1.4 7.8 40.8 0.14 11.0 26.3 3.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Seryl_tRNA_N PF02403.22 CAM36516.1 - 1.9 8.8 37.3 1.3 9.3 1.2 4.5 1 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain V_ATPase_I PF01496.19 CAM36516.1 - 6.2 4.6 27.6 0.12 10.2 17.3 2.2 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family UPF0242 PF06785.11 CAM36516.1 - 7.8 6.6 39.0 2.2 8.3 23.7 3.5 1 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus BLOC1_2 PF10046.9 CAM36516.1 - 8.3 6.8 31.2 0.88 9.9 2.9 5.1 3 1 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4375 PF14300.6 CAM36516.1 - 9.7 6.5 9.5 5.7 7.2 5.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4375) RMI1_N PF08585.12 CAM36517.1 - 1.5e-25 90.3 0.4 4.8e-25 88.6 0.4 1.7 1 1 0 1 1 1 1 RecQ mediated genome instability protein Methyltransf_16 PF10294.9 CAM36518.1 - 6.9e-17 61.7 0.0 9.7e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 CAM36518.1 - 6e-08 33.3 0.0 2.6e-07 31.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAM36518.1 - 6.9e-08 32.4 0.0 1e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAM36518.1 - 9.7e-08 32.6 0.1 1.7e-07 31.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CAM36518.1 - 3.1e-05 23.6 0.0 4.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain tRNA_U5-meth_tr PF05958.11 CAM36518.1 - 5.7e-05 22.3 0.0 7.8e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_11 PF08241.12 CAM36518.1 - 0.00062 20.4 0.1 0.0015 19.1 0.1 1.7 1 1 1 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CAM36518.1 - 0.0008 18.9 0.0 0.0011 18.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 CAM36518.1 - 0.003 17.2 0.0 0.0046 16.6 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_23 PF13489.6 CAM36518.1 - 0.011 15.5 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 CAM36518.1 - 0.034 13.1 0.0 0.054 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) RrnaAD PF00398.20 CAM36518.1 - 0.067 12.2 0.0 0.095 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Met_10 PF02475.16 CAM36518.1 - 0.17 11.6 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein NTP_transferase PF00483.23 CAM36519.1 - 1e-47 162.8 0.0 1.3e-47 162.5 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 CAM36519.1 - 7.4e-12 44.5 13.8 5.4e-06 25.9 1.3 3.7 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 CAM36519.1 - 1.9e-11 44.5 0.0 2.7e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 CAM36519.1 - 8.2e-07 28.3 0.8 0.002 17.1 0.1 2.3 2 1 1 3 3 3 2 L-fucokinase DUF4954 PF16314.5 CAM36519.1 - 0.0086 14.3 1.6 0.013 13.6 1.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 CAM36519.1 - 0.025 14.3 18.3 0.21 11.4 0.3 3.9 3 1 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.19 CAM36519.1 - 0.061 13.2 0.0 0.092 12.7 0.0 1.2 1 0 0 1 1 1 0 Cytidylyltransferase Beach PF02138.18 CAM36520.2 - 5.3e-99 331.1 0.0 8.3e-99 330.4 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain Laminin_G_3 PF13385.6 CAM36520.2 - 0.00042 20.5 0.0 0.0013 18.9 0.0 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.6 CAM36520.2 - 0.038 14.1 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 PH domain associated with Beige/BEACH Pro_isomerase PF00160.21 CAM36521.1 - 2.6e-13 50.5 0.0 3.2e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ATP-synt_C PF00137.21 CAM36522.1 - 8.3e-26 90.1 35.1 2.8e-15 56.4 14.6 2.3 2 0 0 2 2 2 2 ATP synthase subunit C DUF4064 PF13273.6 CAM36522.1 - 0.35 11.1 17.5 0.66 10.3 8.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) GerA PF03323.13 CAM36522.1 - 2 6.8 9.1 2.1 6.7 0.9 2.1 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein Abhydrolase_6 PF12697.7 CAM36523.1 - 3.1e-16 60.6 3.4 5e-16 60.0 3.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CAM36523.1 - 8e-15 55.2 0.1 2.5e-14 53.6 0.1 1.8 2 1 0 3 3 3 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CAM36523.1 - 1.8e-10 40.5 0.1 3.1e-10 39.7 0.1 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 CAM36523.1 - 0.0028 17.5 0.1 0.0066 16.3 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase LIDHydrolase PF10230.9 CAM36523.1 - 0.058 12.9 0.0 0.089 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Glyco_transf_4 PF13439.6 CAM36523.1 - 0.091 12.8 2.8 2 8.4 0.0 2.9 2 1 1 3 3 3 0 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 CAM36523.1 - 0.16 12.4 5.0 4.9 7.6 0.1 2.8 2 1 1 3 3 3 0 Glycosyl transferase 4-like domain LRR_6 PF13516.6 CAM36524.1 - 2.4e-11 42.7 11.6 0.00042 20.1 0.0 8.4 10 0 0 10 10 10 3 Leucine Rich repeat cNMP_binding PF00027.29 CAM36525.1 - 6.2e-07 29.4 0.0 0.046 13.8 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 CAM36525.1 - 0.11 12.2 0.1 7.4 6.4 0.1 2.5 2 0 0 2 2 2 0 Cupin domain DUF3287 PF11690.8 CAM36526.1 - 0.034 13.9 2.6 0.059 13.1 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) SPAM PF02090.15 CAM36526.1 - 0.048 13.5 7.5 0.24 11.2 7.5 2.0 1 1 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein Atg14 PF10186.9 CAM36526.1 - 0.098 11.7 3.6 0.13 11.3 3.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PI-PLC-C1 PF16670.5 CAM36528.2 - 0.089 11.8 0.7 0.11 11.5 0.7 1.1 1 0 0 1 1 1 0 Phosphoinositide phospholipase C, Ca2+-dependent YjgF_endoribonc PF14588.6 CAM36529.1 - 7.6e-31 107.3 0.1 8.3e-31 107.1 0.1 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 CAM36529.1 - 9.8e-21 74.0 0.1 1.3e-20 73.6 0.1 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP ABC_membrane PF00664.23 CAM36530.1 - 4.1e-57 193.9 33.4 3.1e-29 102.5 14.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CAM36530.1 - 1.8e-48 164.5 0.0 2.1e-24 86.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CAM36530.1 - 1.6e-07 31.0 2.4 0.14 11.6 0.0 4.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CAM36530.1 - 2.1e-07 30.6 0.8 0.013 15.2 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 CAM36530.1 - 8e-07 28.7 0.2 0.0051 16.2 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_22 PF13401.6 CAM36530.1 - 1.5e-06 28.5 0.2 0.0055 17.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 CAM36530.1 - 3.2e-06 27.6 0.1 0.0045 17.4 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain T2SSE PF00437.20 CAM36530.1 - 7.5e-06 25.2 0.0 0.0079 15.3 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_21 PF13304.6 CAM36530.1 - 9.7e-06 25.6 0.0 0.015 15.1 0.0 3.2 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system Viral_helicase1 PF01443.18 CAM36530.1 - 1.5e-05 24.9 0.0 0.0045 16.8 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 CAM36530.1 - 0.00012 22.1 0.4 0.013 15.4 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 CAM36530.1 - 0.00013 21.6 0.3 0.015 14.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CAM36530.1 - 0.00022 21.3 0.4 0.83 9.8 0.2 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 CAM36530.1 - 0.00026 21.6 0.0 0.1 13.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 CAM36530.1 - 0.00026 21.1 3.1 0.28 11.2 0.7 2.3 2 0 0 2 2 2 2 Helicase HerA, central domain NACHT PF05729.12 CAM36530.1 - 0.00073 19.5 0.9 0.17 11.8 0.1 2.5 2 0 0 2 2 2 1 NACHT domain TrwB_AAD_bind PF10412.9 CAM36530.1 - 0.0052 15.7 0.4 1.2 8.0 0.0 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 CAM36530.1 - 0.0053 16.4 2.3 0.47 10.0 0.2 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CAM36530.1 - 0.0072 16.1 0.2 1.3 8.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CAM36530.1 - 0.0098 15.4 0.4 1.5 8.3 0.1 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 CAM36530.1 - 0.013 15.7 0.2 1.7 8.8 0.2 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CAM36530.1 - 0.02 15.3 0.1 1.6 9.2 0.0 2.5 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.17 CAM36530.1 - 0.025 14.4 1.1 3.9 7.2 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 CAM36530.1 - 0.027 13.8 0.1 8.2 5.6 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin Roc PF08477.13 CAM36530.1 - 0.048 13.9 1.5 13 6.0 0.3 3.0 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 CAM36530.1 - 0.052 13.6 0.2 1.7 8.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CAM36530.1 - 0.067 12.4 0.5 11 5.1 0.2 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.6 CAM36530.1 - 0.076 13.6 0.1 4.8 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CAM36530.1 - 0.12 12.1 0.4 8.5 6.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 CAM36530.1 - 0.13 12.5 0.3 0.52 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 CAM36530.1 - 0.27 11.3 2.5 7.5 6.6 0.2 2.4 2 0 0 2 2 2 0 Dynamin family Septin PF00735.18 CAM36530.1 - 0.29 10.4 0.4 5.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_19 PF13245.6 CAM36530.1 - 0.33 11.3 0.8 17 5.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain Pox_A32 PF04665.12 CAM36530.1 - 0.44 10.0 1.5 18 4.7 0.3 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein Yip1 PF04893.17 CAM36534.1 - 4.7e-17 62.2 17.5 6.4e-17 61.8 17.4 1.3 1 1 0 1 1 1 1 Yip1 domain ABC_membrane PF00664.23 CAM36535.2 - 1.6e-71 241.2 20.7 6.2e-39 134.3 12.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CAM36535.2 - 5.1e-48 163.1 0.0 1.6e-24 86.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 CAM36535.2 - 1.3e-08 34.4 0.6 0.001 18.8 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 CAM36535.2 - 1.8e-07 30.8 4.1 0.098 12.1 0.1 4.1 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.18 CAM36535.2 - 2.6e-06 27.0 0.6 0.014 14.7 0.1 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_21 PF13304.6 CAM36535.2 - 5e-06 26.5 0.0 0.085 12.6 0.0 3.7 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 CAM36535.2 - 1.7e-05 25.1 0.2 0.081 13.2 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 CAM36535.2 - 2.2e-05 24.1 0.1 0.0038 16.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 CAM36535.2 - 5.5e-05 23.8 0.0 0.023 15.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CAM36535.2 - 7.9e-05 22.6 0.5 0.009 15.9 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 CAM36535.2 - 8.6e-05 23.0 0.3 0.13 12.6 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain T2SSE PF00437.20 CAM36535.2 - 0.00018 20.7 0.0 0.18 10.8 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.23 CAM36535.2 - 0.00021 21.3 0.5 0.82 9.8 0.2 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF87 PF01935.17 CAM36535.2 - 0.0005 20.2 2.1 0.85 9.7 0.1 2.3 2 0 0 2 2 2 2 Helicase HerA, central domain NACHT PF05729.12 CAM36535.2 - 0.0028 17.6 0.7 0.76 9.7 0.1 2.5 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 CAM36535.2 - 0.0033 17.6 0.1 0.55 10.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.9 CAM36535.2 - 0.0033 16.4 0.1 0.89 8.4 0.0 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain Viral_helicase1 PF01443.18 CAM36535.2 - 0.0042 16.8 0.0 1.4 8.6 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase CAP_GLY PF01302.25 CAM36535.2 - 0.0054 16.7 0.0 0.017 15.1 0.0 1.8 1 0 0 1 1 1 1 CAP-Gly domain AAA_30 PF13604.6 CAM36535.2 - 0.0055 16.5 0.5 0.65 9.7 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CAM36535.2 - 0.0058 17.2 0.0 0.46 11.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CAM36535.2 - 0.014 15.8 0.1 1.1 9.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 CAM36535.2 - 0.017 14.6 0.3 2.9 7.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Dynamin_N PF00350.23 CAM36535.2 - 0.018 15.1 0.5 1.7 8.7 0.0 2.4 2 0 0 2 2 2 0 Dynamin family cobW PF02492.19 CAM36535.2 - 0.019 14.6 0.7 5.1 6.6 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 CAM36535.2 - 0.038 14.2 0.5 13 6.0 0.3 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 CAM36535.2 - 0.039 13.7 2.5 2.5 7.8 0.2 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 CAM36535.2 - 0.051 12.9 0.1 11 5.2 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Ploopntkinase3 PF18751.1 CAM36535.2 - 0.076 12.9 0.5 1.7 8.5 0.0 2.7 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 AAA_14 PF13173.6 CAM36535.2 - 0.091 12.8 0.1 4.1 7.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CAM36535.2 - 0.15 12.3 0.1 0.99 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 CAM36535.2 - 0.28 10.4 0.4 5.4 6.2 0.0 2.1 2 0 0 2 2 2 0 Septin adh_short_C2 PF13561.6 CAM36537.1 - 3e-34 118.6 0.4 1.1e-29 103.6 0.0 2.3 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CAM36537.1 - 2.7e-26 92.2 0.0 4.8e-24 84.9 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase zf-C3HC4 PF00097.25 CAM36538.1 - 7.9e-07 28.9 7.8 2.1e-06 27.5 7.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CAM36538.1 - 1.1e-05 25.4 6.7 3.1e-05 23.9 6.7 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CAM36538.1 - 0.0011 19.0 8.6 0.0024 18.0 8.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 CAM36538.1 - 0.0056 16.5 8.7 0.0056 16.5 8.7 2.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CAM36538.1 - 0.042 13.8 10.8 0.11 12.5 10.8 1.7 1 0 0 1 1 1 0 zinc-RING finger domain RNA_POL_M_15KD PF02150.16 CAM36538.1 - 0.09 12.7 3.3 0.19 11.6 3.3 1.5 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit zf-RING_2 PF13639.6 CAM36538.1 - 0.34 11.3 10.8 0.23 11.8 8.3 2.1 2 0 0 2 2 2 0 Ring finger domain zf-RING_6 PF14835.6 CAM36538.1 - 0.46 10.4 6.7 2.1 8.3 6.7 2.0 1 1 0 1 1 1 0 zf-RING of BARD1-type protein TF_Zn_Ribbon PF08271.12 CAM36538.1 - 0.83 9.2 5.2 2 8.0 5.2 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding zf-C3HC4_3 PF13920.6 CAM36538.1 - 1.3 9.0 8.7 3.4 7.6 8.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CAM36538.1 - 2.1 8.3 7.1 7.3 6.5 6.8 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CAM36538.1 - 3.7 7.9 6.2 11 6.3 6.2 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain Hus1 PF04005.12 CAM36539.1 - 8.1e-79 264.8 0.0 9.4e-79 264.5 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein tRNA-synt_1b PF00579.25 CAM36540.1 - 3.2e-17 62.8 0.0 6.4e-17 61.8 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Opi1 PF08618.10 CAM36540.1 - 0.011 15.0 0.3 0.016 14.5 0.3 1.1 1 0 0 1 1 1 0 Transcription factor Opi1 MSA-2c PF12238.8 CAM36540.1 - 0.13 12.3 1.5 0.61 10.1 1.5 1.9 2 0 0 2 2 2 0 Merozoite surface antigen 2c DUF1799 PF08809.11 CAM36540.1 - 0.18 12.0 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 Phage related hypothetical protein (DUF1799) AAA_16 PF13191.6 CAM36541.1 - 0.0018 18.7 0.0 0.0043 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CAM36541.1 - 0.003 17.6 0.0 0.009 16.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CAM36541.1 - 0.0074 16.6 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CAM36541.1 - 0.0082 16.3 0.1 0.043 14.0 0.0 2.1 1 1 1 2 2 2 1 AAA domain ABC_tran PF00005.27 CAM36541.1 - 0.012 16.2 0.0 0.025 15.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.21 CAM36541.1 - 0.017 14.5 1.1 0.17 11.2 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CAM36541.1 - 0.017 15.6 0.1 0.059 13.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain tRNA_lig_kinase PF08303.11 CAM36541.1 - 0.021 14.9 0.0 0.15 12.2 0.0 2.1 1 1 0 1 1 1 0 tRNA ligase kinase domain RNA_helicase PF00910.22 CAM36541.1 - 0.037 14.4 0.0 0.079 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 CAM36541.1 - 0.11 12.9 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 CAM36541.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_15 PF13175.6 CAM36541.1 - 0.14 11.9 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 CAM36541.1 - 0.16 11.9 0.0 0.41 10.5 0.0 1.7 1 0 0 1 1 1 0 NACHT domain zf-RING_13 PF17977.1 CAM36542.2 - 0.026 14.6 0.1 0.065 13.4 0.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain V-ATPase_G PF03179.15 CAM36544.1 - 7.4e-21 74.7 13.5 8.1e-21 74.5 13.5 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit RHH_5 PF07878.11 CAM36544.1 - 0.11 12.5 0.9 0.2 11.6 0.1 1.8 2 0 0 2 2 2 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 V-ATPase_G_2 PF16999.5 CAM36544.1 - 0.72 10.3 14.2 0.86 10.1 14.2 1.1 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit KptA_kDCL PF18176.1 CAM36546.1 - 4.6e-50 169.7 0.0 1.6e-49 167.9 0.0 2.0 2 0 0 2 2 2 1 KptA in kinetoplastid DICER domain PPL4 PF18188.1 CAM36546.1 - 4.1e-45 153.6 0.0 8.9e-45 152.5 0.0 1.6 1 0 0 1 1 1 1 Prim-pol 4 La_HTH_kDCL PF18177.1 CAM36546.1 - 8.4e-30 102.9 0.0 2.1e-29 101.6 0.0 1.7 1 0 0 1 1 1 1 La HTH in kinetoplastid DICER domain Ribonucleas_3_3 PF14622.6 CAM36546.1 - 0.0042 17.3 0.0 2.4 8.4 0.0 3.5 3 0 0 3 3 3 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 CAM36546.1 - 0.017 15.7 0.1 18 6.0 0.0 3.1 3 0 0 3 3 3 0 Ribonuclease III domain ADH_N PF08240.12 CAM36547.1 - 2.1e-27 95.1 12.2 2.2e-27 95.1 8.4 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CAM36547.1 - 3.4e-22 78.8 0.0 6.3e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 CAM36547.1 - 5.1e-07 29.2 0.1 8.3e-07 28.5 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Glu_dehyd_C PF16912.5 CAM36547.1 - 6.1e-07 29.1 0.3 8.9e-07 28.6 0.3 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus 2-Hacid_dh_C PF02826.19 CAM36547.1 - 3.1e-06 26.7 0.1 5e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 CAM36547.1 - 1.2e-05 26.4 0.0 2.2e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_2 PF03446.15 CAM36547.1 - 0.0002 21.6 0.3 0.00034 20.8 0.3 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 CAM36547.1 - 0.011 15.7 0.2 0.018 14.9 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 CAM36547.1 - 0.028 14.5 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 CAM36547.1 - 0.063 12.9 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF364 PF04016.12 CAM36547.1 - 0.076 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative heavy-metal chelation ABC_tran PF00005.27 CAM36549.2 - 4.4e-30 105.0 0.0 7.3e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 CAM36549.2 - 3.8e-23 82.0 19.4 3.8e-23 82.0 19.4 2.8 3 0 0 3 3 3 1 ABC-2 type transporter AAA_16 PF13191.6 CAM36549.2 - 9.9e-05 22.8 0.1 0.0003 21.2 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 CAM36549.2 - 0.00062 19.7 0.1 0.3 10.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CAM36549.2 - 0.00071 19.3 0.0 0.0023 17.6 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CAM36549.2 - 0.0016 18.4 0.2 0.0035 17.3 0.2 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 CAM36549.2 - 0.0083 16.4 0.1 0.025 14.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 CAM36549.2 - 0.019 15.4 0.0 0.035 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CAM36549.2 - 0.09 12.5 0.2 0.17 11.6 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CAM36549.2 - 0.091 13.3 0.3 0.18 12.4 0.3 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 CAM36549.2 - 0.096 12.6 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain ABC2_membrane_3 PF12698.7 CAM36549.2 - 0.17 10.9 25.7 0.067 12.3 20.8 2.3 2 0 0 2 2 2 0 ABC-2 family transporter protein AAA_25 PF13481.6 CAM36549.2 - 0.2 11.2 0.3 0.43 10.1 0.3 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CAM36549.2 - 0.38 11.0 3.5 0.31 11.2 0.7 2.1 2 0 0 2 2 2 0 AAA domain Cmc1 PF08583.10 CAM36550.2 - 0.096 12.7 1.0 0.2 11.7 1.0 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Hormone_5 PF00184.17 CAM36552.1 - 0.13 13.1 1.6 0.16 12.8 0.6 1.6 1 1 1 2 2 2 0 Neurohypophysial hormones, C-terminal Domain Aldose_epim PF01263.20 CAM36553.1 - 3.4e-54 184.2 0.0 8e-54 183.0 0.0 1.5 1 1 0 1 1 1 1 Aldose 1-epimerase FtsX PF02687.21 CAM36555.1 - 4.3e-14 52.8 21.9 4e-10 40.0 10.7 7.0 7 1 0 7 7 7 2 FtsX-like permease family Transketolase_C PF02780.20 CAM36555.1 - 0.031 14.1 0.0 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 Transketolase, C-terminal domain CHAP PF05257.16 CAM36556.2 - 9.6e-10 38.9 0.8 1.6e-08 35.0 0.8 2.4 1 1 0 1 1 1 1 CHAP domain AMPKBI PF04739.15 CAM36559.2 - 5.6e-14 52.2 1.5 5.6e-14 52.2 1.5 1.8 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 CAM36559.2 - 2.5e-08 34.0 0.0 4.8e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase PAP2_3 PF14378.6 CAM36560.1 - 0.092 12.4 5.8 3.9 7.1 5.8 2.4 1 1 0 1 1 1 0 PAP2 superfamily Arnt_C PF18583.1 CAM36562.1 - 0.071 12.7 0.2 0.13 11.9 0.2 1.4 1 0 0 1 1 1 0 Aminoarabinose transferase C-terminal domain SET PF00856.28 CAM36563.1 - 4.6e-12 46.6 0.0 1.9e-11 44.6 0.0 1.8 1 1 0 1 1 1 1 SET domain FtsJ PF01728.19 CAM36564.1 - 2.6e-47 161.2 0.0 3.1e-47 161.0 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 CAM36564.1 - 0.0028 17.5 0.0 0.0059 16.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAM36564.1 - 0.068 13.9 0.5 0.96 10.2 0.5 2.6 1 1 0 1 1 1 0 Methyltransferase domain AMP-binding PF00501.28 CAM36565.1 - 1.8e-86 290.4 0.0 2.2e-86 290.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CAM36565.1 - 2.6e-18 66.8 2.4 5.1e-18 65.8 2.4 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 CAM36565.1 - 5.3e-17 61.5 3.4 1.3e-16 60.3 3.4 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus EF-hand_6 PF13405.6 CAM36566.1 - 7.6e-07 28.6 0.1 0.041 13.8 0.0 3.3 3 1 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 CAM36566.1 - 2.2e-06 27.4 0.7 0.085 12.7 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.6 CAM36566.1 - 2e-05 25.0 0.0 0.00029 21.2 0.0 2.5 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CAM36566.1 - 5.7e-05 22.4 0.0 0.007 15.8 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 CAM36566.1 - 0.0083 15.6 0.1 0.94 9.1 0.0 2.5 2 0 0 2 2 2 1 EF hand DprA_WH PF17782.1 CAM36566.1 - 0.061 13.4 1.3 0.27 11.4 0.1 2.7 3 0 0 3 3 3 0 DprA winged helix domain XRN_N PF03159.18 CAM36567.2 - 2.5e-59 200.6 0.0 4.1e-59 199.9 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 CAM36567.2 - 7.6e-07 28.4 12.9 0.00026 20.1 0.0 4.0 4 0 0 4 4 4 3 Xrn1 helical domain DUF4587 PF15248.6 CAM36567.2 - 2.2 9.1 6.6 22 5.9 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4587) GFO_IDH_MocA PF01408.22 CAM36569.1 - 4.1e-09 37.3 0.0 1.3e-08 35.7 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 CAM36569.1 - 0.00043 20.8 0.1 0.0015 19.1 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent CoA_binding_3 PF13727.6 CAM36569.1 - 0.016 15.2 0.0 0.038 14.0 0.0 1.6 1 0 0 1 1 1 0 CoA-binding domain CAF1 PF04857.20 CAM36572.1 - 7.3e-71 238.9 0.0 9e-71 238.6 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease Kelch_4 PF13418.6 CAM36573.2 - 7.6e-12 45.0 8.6 0.001 19.0 0.0 5.7 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 CAM36573.2 - 5.3e-10 39.1 14.5 0.0022 17.9 0.6 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 CAM36573.2 - 4.2e-09 36.5 12.1 2.2e-06 27.8 0.4 5.4 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.25 CAM36573.2 - 4.4e-09 35.8 12.2 0.00046 19.7 0.1 5.6 5 1 0 5 5 5 2 Kelch motif Kelch_6 PF13964.6 CAM36573.2 - 2e-06 27.9 9.3 0.65 10.4 0.1 5.6 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 CAM36573.2 - 6.6e-05 22.7 8.4 2.3 8.3 0.1 5.8 5 1 0 5 5 5 2 Kelch motif tRNA_bind PF01588.20 CAM36574.1 - 1.8e-12 47.2 0.4 2.5e-12 46.7 0.4 1.2 1 0 0 1 1 1 1 Putative tRNA binding domain zf-RanBP PF00641.18 CAM36574.1 - 0.00067 18.9 4.4 0.0012 18.1 4.4 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-ribbon_3 PF13248.6 CAM36574.1 - 0.038 13.4 1.8 0.088 12.2 1.8 1.6 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.7 CAM36574.1 - 0.05 13.6 2.8 0.088 12.8 2.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon PvlArgDC PF01862.16 CAM36574.1 - 0.1 12.4 0.2 0.2 11.5 0.2 1.5 1 1 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) zinc_ribbon_2 PF13240.6 CAM36574.1 - 0.2 11.4 2.5 0.42 10.4 2.5 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Lactamase_B PF00753.27 CAM36575.1 - 1.6e-08 34.8 0.4 2.1e-06 27.9 0.2 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily PAP2 PF01569.21 CAM36576.1 - 1.2e-06 28.4 6.4 1.2e-06 28.4 6.4 2.8 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 CAM36576.1 - 1 9.5 8.0 2 8.6 1.6 2.9 2 1 0 2 2 2 0 Divergent PAP2 family ThiF PF00899.21 CAM36577.1 - 4.4e-89 298.0 0.2 6e-64 215.7 0.0 2.6 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 CAM36577.1 - 1.1e-64 218.8 0.6 1.6e-64 218.2 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 CAM36577.1 - 1.2e-10 41.9 0.0 2.4e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 CAM36577.1 - 0.0002 21.5 0.0 0.00051 20.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 CAM36577.1 - 0.00083 19.5 0.0 0.0023 18.1 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Shikimate_DH PF01488.20 CAM36577.1 - 0.00091 19.3 0.4 0.6 10.2 0.0 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Kinesin PF00225.23 CAM36578.1 - 1.2e-86 290.6 0.0 3.2e-86 289.3 0.0 1.7 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CAM36578.1 - 8.6e-16 58.2 0.0 4.2e-15 56.0 0.0 2.2 1 1 0 1 1 1 1 Microtubule binding Maelstrom PF13017.6 CAM36578.1 - 0.028 14.1 0.2 0.99 9.0 0.1 2.3 2 0 0 2 2 2 0 piRNA pathway germ-plasm component MYCBPAP PF14646.6 CAM36579.1 - 3.8e-10 39.3 5.8 3.2e-09 36.2 0.2 2.7 2 1 0 2 2 2 2 MYCBP-associated protein family ABC_membrane PF00664.23 CAM36581.1 - 2.4e-53 181.6 29.9 2e-33 116.3 7.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CAM36581.1 - 1.4e-48 164.9 0.0 1.6e-24 86.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 CAM36581.1 - 2.2e-07 30.5 0.8 0.013 15.3 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 CAM36581.1 - 4.2e-07 29.6 4.3 0.14 11.5 0.0 4.3 3 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.18 CAM36581.1 - 9.3e-07 28.4 0.2 0.0051 16.2 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_22 PF13401.6 CAM36581.1 - 2e-06 28.1 0.4 0.0054 17.0 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CAM36581.1 - 6.1e-06 26.7 0.1 0.0044 17.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 CAM36581.1 - 9.3e-06 25.7 0.0 0.015 15.1 0.0 3.3 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 CAM36581.1 - 9.3e-06 24.9 0.0 0.0079 15.3 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein Viral_helicase1 PF01443.18 CAM36581.1 - 1.4e-05 25.0 0.0 0.0045 16.8 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 CAM36581.1 - 0.00011 22.1 0.4 0.013 15.4 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 CAM36581.1 - 0.00015 21.4 0.3 0.015 14.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CAM36581.1 - 0.00021 21.4 0.4 0.82 9.8 0.2 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 CAM36581.1 - 0.00025 21.6 0.0 0.1 13.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 CAM36581.1 - 0.00027 21.1 3.1 0.28 11.2 0.7 2.3 2 0 0 2 2 2 2 Helicase HerA, central domain NACHT PF05729.12 CAM36581.1 - 0.00074 19.5 0.9 0.17 11.8 0.1 2.5 2 0 0 2 2 2 1 NACHT domain TrwB_AAD_bind PF10412.9 CAM36581.1 - 0.0049 15.8 0.4 1.2 8.0 0.0 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 CAM36581.1 - 0.0049 16.5 2.3 0.47 10.0 0.2 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 CAM36581.1 - 0.0088 15.6 0.4 1.5 8.3 0.1 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 CAM36581.1 - 0.009 15.7 0.2 1.3 8.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CAM36581.1 - 0.012 15.8 0.2 1.7 8.8 0.2 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CAM36581.1 - 0.018 15.4 0.1 1.6 9.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.17 CAM36581.1 - 0.026 14.3 1.1 3.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 CAM36581.1 - 0.027 13.7 0.1 8.1 5.7 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin Roc PF08477.13 CAM36581.1 - 0.038 14.2 0.6 13 6.0 0.3 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 CAM36581.1 - 0.054 13.5 0.1 1.7 8.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CAM36581.1 - 0.067 12.4 0.5 11 5.1 0.2 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.6 CAM36581.1 - 0.074 13.6 0.1 4.8 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CAM36581.1 - 0.13 12.5 0.2 0.52 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CAM36581.1 - 0.15 11.8 0.1 8.8 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 CAM36581.1 - 0.26 11.3 2.5 7.5 6.6 0.2 2.4 2 0 0 2 2 2 0 Dynamin family Septin PF00735.18 CAM36581.1 - 0.28 10.4 0.4 5.4 6.2 0.0 2.2 2 0 0 2 2 2 0 Septin Pox_A32 PF04665.12 CAM36581.1 - 0.4 10.1 1.5 18 4.7 0.3 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_19 PF13245.6 CAM36581.1 - 4.1 7.7 4.6 17 5.8 0.0 3.2 4 0 0 4 4 2 0 AAA domain DIM1 PF02966.16 CAM36582.2 - 1.4e-29 102.5 0.2 3.1e-25 88.5 0.1 2.2 2 0 0 2 2 2 2 Mitosis protein DIM1 PriCT_2 PF08707.11 CAM36585.1 - 1.5e-16 60.5 1.9 3.2e-16 59.5 1.9 1.6 1 0 0 1 1 1 1 Primase C terminal 2 (PriCT-2) PPL5 PF18168.1 CAM36585.1 - 4.8e-07 29.4 3.2 0.00015 21.2 0.0 3.1 3 0 0 3 3 3 2 Prim-pol family 5 DNA_primase_S PF01896.19 CAM36585.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 DNA primase small subunit DUF1738 PF08401.11 CAM36586.1 - 1.2e-05 25.4 0.0 0.00058 20.0 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1738) AMP-binding PF00501.28 CAM36587.1 - 1.1e-84 284.5 0.0 1.3e-84 284.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 CAM36587.1 - 8e-17 60.9 3.8 2e-16 59.7 3.8 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 CAM36587.1 - 8.6e-17 61.9 0.4 1.8e-16 60.8 0.4 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RRM_1 PF00076.22 CAM36588.1 - 1.5e-11 43.9 0.0 2.4e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 CAM36589.1 - 2e-13 49.9 0.0 3.5e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MMR_HSR1 PF01926.23 CAM36590.2 - 1.7e-10 41.0 0.0 5.3e-10 39.4 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CAM36590.2 - 2.7e-05 24.3 0.1 0.00014 21.9 0.1 2.0 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 CAM36590.2 - 7.7e-05 22.7 0.0 0.0039 17.1 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 CAM36590.2 - 0.015 15.1 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Methyltransf_14 PF08484.11 CAM36590.2 - 0.077 12.8 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 C-methyltransferase C-terminal domain ABC_tran PF00005.27 CAM36590.2 - 0.11 13.1 0.0 0.25 11.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter FeoB_N PF02421.18 CAM36590.2 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B Thiolase_N PF00108.23 CAM36591.1 - 2.1e-15 56.8 4.7 5.8e-15 55.3 2.5 2.5 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CAM36591.1 - 7.7e-13 48.2 1.3 2.8e-11 43.2 0.1 2.8 2 1 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CAM36591.1 - 4.9e-09 36.2 0.9 1.1e-07 31.6 0.3 2.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 CAM36591.1 - 0.0065 16.3 1.6 0.69 9.8 1.5 2.7 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.22 CAM36591.1 - 0.98 9.5 5.1 7.1 6.7 0.0 3.5 3 1 1 4 4 4 0 Beta-ketoacyl synthase, C-terminal domain DUF1738 PF08401.11 CAM36592.1 - 0.00027 21.1 0.4 0.27 11.3 0.3 3.0 2 1 1 3 3 3 2 Domain of unknown function (DUF1738) DUF676 PF05057.14 CAM36594.1 - 2.1e-12 47.0 0.0 4.2e-10 39.5 0.0 2.7 2 1 0 2 2 2 2 Putative serine esterase (DUF676) DUF1638 PF07796.11 CAM36594.1 - 0.027 14.6 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1638) Corona_5a PF06336.11 CAM36594.1 - 4.3 7.4 4.8 2.4 8.2 2.0 2.0 2 0 0 2 2 2 0 Coronavirus 5a protein FAD-oxidase_C PF02913.19 CAM36597.1 - 3.5e-47 161.1 0.0 5.1e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CAM36597.1 - 1.6e-29 102.4 1.6 2.8e-29 101.6 0.9 1.8 2 0 0 2 2 2 1 FAD binding domain SET PF00856.28 CAM36598.1 - 9.5e-10 39.1 0.0 1.8e-09 38.2 0.0 1.9 1 1 0 1 1 1 1 SET domain zinc_ribbon_5 PF13719.6 CAM36598.1 - 0.11 12.2 0.4 0.11 12.2 0.4 1.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-MYND PF01753.18 CAM36598.1 - 1.9 8.7 17.3 0.063 13.4 10.2 2.4 2 1 0 2 2 2 0 MYND finger Na_H_Exchanger PF00999.21 CAM36599.1 - 1.8e-48 165.3 41.7 2.6e-48 164.7 41.7 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TetR_C_23 PF17931.1 CAM36599.1 - 0.048 13.8 0.1 0.34 11.0 0.1 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TPR_12 PF13424.6 CAM36603.1 - 0.00018 21.7 0.2 0.47 10.8 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CAM36603.1 - 0.013 16.3 1.3 0.44 11.5 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4919 PF16266.5 CAM36603.1 - 0.083 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) TPR_8 PF13181.6 CAM36603.1 - 0.099 12.9 0.1 2.9 8.3 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Prok-TraM PF09228.10 CAM36603.1 - 0.13 12.7 0.7 0.47 10.9 0.7 1.9 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM TPR_10 PF13374.6 CAM36603.1 - 1.7 8.6 5.5 1.3 9.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ADH_zinc_N_2 PF13602.6 CAM36604.1 - 8.8e-20 72.1 0.0 2.5e-19 70.6 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CAM36604.1 - 1.6e-08 34.4 0.3 6.1e-08 32.5 0.1 2.1 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CAM36604.1 - 5.1e-06 26.5 0.1 4.9e-05 23.3 0.0 2.4 2 1 0 2 2 2 1 Zinc-binding dehydrogenase TMEM187 PF15100.6 CAM36604.1 - 0.069 12.7 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 TMEM187 protein family Glyco_hydro_32N PF00251.20 CAM36605.1 - 3.3e-86 289.6 0.3 5.3e-86 288.9 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 CAM36605.1 - 3.5e-20 72.6 0.0 5.6e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.20 CAM36606.1 - 5.3e-89 298.8 2.2 6.7e-89 298.5 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 CAM36606.1 - 3e-20 72.8 0.0 4.3e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_43 PF04616.14 CAM36606.1 - 3.4e-05 23.3 1.4 4.8e-05 22.8 1.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Methyltransf_28 PF02636.17 CAM36607.1 - 5.7e-60 203.2 0.0 7.8e-60 202.7 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase NIF PF03031.18 CAM36608.1 - 0.011 15.5 0.1 0.035 13.9 0.0 1.8 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase HAD PF12710.7 CAM36608.1 - 0.04 14.3 0.9 0.31 11.4 0.0 2.8 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Peptidase_M17 PF00883.21 CAM36610.1 - 2.2e-103 345.8 0.1 3.5e-103 345.1 0.0 1.3 2 0 0 2 2 2 1 Cytosol aminopeptidase family, catalytic domain CHB_HEX_C_1 PF13290.6 CAM36611.1 - 3.4e-06 27.0 0.3 0.00043 20.2 0.2 3.0 3 0 0 3 3 3 1 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.6 CAM36611.1 - 2.8e-05 24.2 0.3 0.26 11.5 0.0 4.3 5 0 0 5 5 5 2 Fn3 associated TcdB_toxin_midC PF12255.8 CAM36611.1 - 0.078 13.0 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/C-terminal region Svs_4_5_6 PF17381.2 CAM36613.1 - 0.8 10.7 9.5 11 7.1 3.4 2.5 2 0 0 2 2 2 0 Seminal vesicle secretory proteins 4/5/6 Integrin_B_tail PF07965.12 CAM36613.1 - 5.1 7.6 7.5 0.43 11.1 1.5 2.3 3 0 0 3 3 3 0 Integrin beta tail domain OmpH PF03938.14 CAM36615.1 - 0.17 12.2 6.7 0.35 11.2 4.8 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Fib_alpha PF08702.10 CAM36615.1 - 0.98 9.6 4.3 3.1 8.0 1.1 2.5 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF641 PF04859.12 CAM36615.1 - 0.98 9.8 9.4 7.6 6.9 0.2 2.6 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) TMPIT PF07851.13 CAM36615.1 - 1.7 7.8 7.9 0.3 10.3 3.9 1.6 2 0 0 2 2 2 0 TMPIT-like protein Seryl_tRNA_N PF02403.22 CAM36615.1 - 7.1 6.9 11.2 2.2 8.5 4.7 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Spore_YhaL PF14147.6 CAM36617.1 - 0.094 12.4 0.5 0.094 12.4 0.5 2.4 3 0 0 3 3 3 0 Sporulation protein YhaL ATP-synt_B PF00430.18 CAM36617.1 - 9.3 6.4 14.9 1.7 8.7 4.6 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) SelP_N PF04592.14 CAM36618.1 - 4.5 6.6 8.0 5 6.5 8.0 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region KIAA1430 PF13879.6 CAM36620.1 - 0.0039 17.9 0.4 0.0088 16.8 0.4 1.7 1 0 0 1 1 1 1 KIAA1430 homologue Bd3614-deam PF14439.6 CAM36621.2 - 0.081 13.0 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 Bd3614-like deaminase 5-FTHF_cyc-lig PF01812.20 CAM36622.1 - 1.6e-12 47.6 2.5 1.5e-09 38.0 0.0 3.3 4 0 0 4 4 4 2 5-formyltetrahydrofolate cyclo-ligase family HIT PF01230.23 CAM36623.1 - 9.6e-12 45.5 0.1 3e-11 43.9 0.1 1.8 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CAM36623.1 - 6.8e-06 26.5 0.1 4e-05 24.1 0.1 2.1 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding UPF0730 PF15827.5 CAM36623.1 - 0.012 15.3 0.4 0.14 11.9 0.1 2.5 2 0 0 2 2 2 0 UPF0730 unknown protein family VSG_B PF13206.6 CAM36623.1 - 0.049 12.9 2.4 0.078 12.2 2.4 1.3 1 0 0 1 1 1 0 Trypanosomal VSG domain Peptidase_C2 PF00648.21 CAM36623.1 - 0.18 10.8 0.2 0.28 10.2 0.2 1.2 1 0 0 1 1 1 0 Calpain family cysteine protease DUF4835 PF16119.5 CAM36624.1 - 0.2 10.7 0.0 5.3 6.1 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4835) LRR_4 PF12799.7 CAM36626.1 - 7e-16 58.1 7.3 0.0014 19.0 0.0 7.3 4 2 4 9 9 9 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CAM36626.1 - 0.00027 20.9 1.8 1 9.3 0.0 3.5 2 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 CAM36626.1 - 0.00059 19.5 14.5 2.4 8.0 0.8 6.9 5 1 3 8 8 8 3 Leucine rich repeat LRR_1 PF00560.33 CAM36626.1 - 0.0015 18.8 8.4 30 5.7 0.0 6.8 7 1 0 7 7 7 2 Leucine Rich Repeat Stealth_CR2 PF11380.8 CAM36627.1 - 3e-25 88.5 0.2 4.6e-20 71.8 0.0 2.6 2 0 0 2 2 2 2 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 CAM36627.1 - 1.1e-11 44.4 0.3 3.1e-11 43.0 0.3 1.8 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 DUF2270 PF10028.9 CAM36627.1 - 0.056 13.0 0.3 0.1 12.2 0.3 1.3 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2270) CH PF00307.31 CAM36628.1 - 0.0026 17.9 0.1 0.0062 16.7 0.1 1.6 1 1 0 1 1 1 1 Calponin homology (CH) domain Pox_A_type_inc PF04508.12 CAM36629.1 - 7.3e-06 25.6 4.1 0.25 11.3 0.0 4.4 3 0 0 3 3 3 2 Viral A-type inclusion protein repeat Cnn_1N PF07989.11 CAM36629.1 - 0.00024 21.2 0.9 0.00024 21.2 0.9 4.6 5 0 0 5 5 5 1 Centrosomin N-terminal motif 1 CENP-F_leu_zip PF10473.9 CAM36629.1 - 0.0038 17.3 4.6 0.0038 17.3 4.6 5.4 4 1 1 5 5 5 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DHR10 PF18595.1 CAM36629.1 - 0.0054 16.8 8.5 0.0054 16.8 8.5 5.0 5 1 0 5 5 5 1 Designed helical repeat protein 10 domain DUF16 PF01519.16 CAM36629.1 - 0.0081 16.6 4.7 0.0081 16.6 4.7 3.9 3 1 1 4 4 4 1 Protein of unknown function DUF16 DivIC PF04977.15 CAM36629.1 - 0.19 11.5 30.6 0.35 10.7 1.3 5.8 5 1 1 6 6 6 0 Septum formation initiator DUF5082 PF16888.5 CAM36629.1 - 1 9.6 11.4 16 5.8 2.0 4.1 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) Bacillus_HBL PF05791.11 CAM36629.1 - 4.8 7.0 6.3 1 9.1 1.9 2.1 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Syntaxin_2 PF14523.6 CAM36629.1 - 6.2 7.3 8.5 0.34 11.3 0.7 2.7 3 0 0 3 3 3 0 Syntaxin-like protein DUF3450 PF11932.8 CAM36629.1 - 8.6 5.6 26.4 1.1 8.6 0.9 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3450) Sipho_Gp157 PF05565.11 CAM36629.1 - 9 6.3 10.2 1.3 9.0 0.7 3.0 2 1 1 3 3 3 0 Siphovirus Gp157 NPV_P10 PF05531.12 CAM36630.1 - 1.7 9.1 12.8 4.5 7.8 0.1 4.9 5 1 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Pox_A_type_inc PF04508.12 CAM36630.1 - 5.4 7.0 13.7 3.5 7.6 0.1 4.7 4 1 0 4 4 4 0 Viral A-type inclusion protein repeat JUPITER PF17054.5 CAM36631.1 - 0.015 14.8 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter DUF4061 PF13270.6 CAM36631.1 - 1.3 9.4 7.1 4.4 7.7 0.5 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4061) WD40_4 PF16300.5 CAM36633.1 - 1.1e-11 44.5 0.0 2.1e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Type of WD40 repeat DUF1899 PF08953.11 CAM36633.1 - 7.4e-11 41.8 0.0 1.3e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.32 CAM36633.1 - 0.00047 20.9 5.5 0.17 12.8 0.1 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM36633.1 - 0.017 15.4 0.1 0.16 12.3 0.1 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_S9 PF00380.19 CAM36634.1 - 0.00028 21.4 0.0 0.00054 20.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 TMEM234 PF10639.9 CAM36635.1 - 6.4e-36 122.9 1.0 7.7e-36 122.7 1.0 1.0 1 0 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 CAM36635.1 - 1.8e-08 34.6 5.5 0.00015 22.0 2.4 2.1 2 0 0 2 2 2 2 EamA-like transporter family Herpes_LMP1 PF05297.11 CAM36635.1 - 0.0048 16.2 0.7 0.0048 16.2 0.7 1.4 2 0 0 2 2 2 1 Herpesvirus latent membrane protein 1 (LMP1) His_Phos_2 PF00328.22 CAM36636.1 - 3.2e-10 39.9 0.2 4.4e-07 29.6 0.0 2.9 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Cytomega_UL20A PF05984.12 CAM36636.1 - 0.15 12.4 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein Methyltransf_5 PF01795.19 CAM36637.2 - 5.7e-28 98.3 0.0 7.9e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 MraW methylase family Methyltransf_31 PF13847.6 CAM36637.2 - 7.1e-06 25.9 0.0 0.00026 20.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAM36637.2 - 9.4e-05 23.0 0.0 0.0017 19.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAM36637.2 - 0.014 16.0 0.0 0.38 11.4 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 CAM36637.2 - 0.11 12.1 0.0 0.27 10.8 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain SIR2 PF02146.17 CAM36638.1 - 4.1e-35 121.3 0.1 8.3e-34 117.0 0.1 2.1 1 1 0 1 1 1 1 Sir2 family Cpn60_TCP1 PF00118.24 CAM36639.1 - 7.9e-160 532.7 4.3 9.5e-160 532.4 4.3 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PPR_1 PF12854.7 CAM36641.1 - 9.3e-06 25.2 0.0 2.1e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 PPR repeat PPR_3 PF13812.6 CAM36641.1 - 2.7e-05 24.2 0.0 5.3e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR_2 PF13041.6 CAM36641.1 - 0.00028 21.0 0.0 0.0013 18.9 0.0 2.1 2 0 0 2 2 2 1 PPR repeat family PPR PF01535.20 CAM36641.1 - 0.0046 17.1 0.5 0.014 15.6 0.1 2.1 2 0 0 2 2 2 1 PPR repeat SAP130_C PF16014.5 CAM36641.1 - 0.063 12.4 5.9 0.068 12.3 4.5 1.6 2 0 0 2 2 2 0 Histone deacetylase complex subunit SAP130 C-terminus Xrn1_D3 PF18194.1 CAM36641.1 - 0.1 12.7 0.2 13 6.0 0.0 2.6 2 0 0 2 2 2 0 Exoribonuclease 1 Domain-3 Ribos_L4_asso_C PF14374.6 CAM36641.1 - 0.12 12.5 0.5 0.33 11.0 0.5 1.8 1 0 0 1 1 1 0 60S ribosomal protein L4 C-terminal domain C2-C2_1 PF11618.8 CAM36642.1 - 5.9e-29 100.9 3.0 7.8e-28 97.3 0.6 3.4 2 1 1 3 3 3 1 First C2 domain of RPGR-interacting protein 1 Macoilin PF09726.9 CAM36642.1 - 0.0083 14.7 1.1 0.0083 14.7 1.1 3.5 2 1 1 3 3 3 1 Macoilin family KNOX2 PF03791.13 CAM36642.1 - 0.027 13.9 0.2 0.083 12.4 0.2 1.8 1 0 0 1 1 1 0 KNOX2 domain GAS PF13851.6 CAM36642.1 - 0.29 10.5 31.0 0.58 9.5 8.6 3.5 2 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding YabA PF06156.13 CAM36642.1 - 5.4 7.7 25.8 1.4 9.6 0.2 4.7 2 1 2 4 4 4 0 Initiation control protein YabA RICTOR_M PF14666.6 CAM36643.1 - 6.8e-22 77.2 0.0 2.4e-20 72.2 0.0 3.3 2 1 1 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_N PF14664.6 CAM36643.1 - 3.3e-16 59.3 0.3 2.7e-13 49.7 0.0 2.7 3 0 0 3 3 3 2 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 CAM36643.1 - 4.6e-12 46.3 2.7 4.9e-12 46.2 0.5 2.3 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 CAM36643.1 - 0.00025 21.2 0.5 0.0086 16.3 0.1 3.5 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 DUF3602 PF12223.8 CAM36643.1 - 0.00057 20.4 1.5 0.29 11.7 0.1 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF3602) XPG_I PF00867.18 CAM36646.1 - 4.9e-17 62.1 0.2 9.1e-16 58.0 0.1 2.4 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 CAM36646.1 - 7.8e-15 55.2 0.0 3.1e-06 27.6 0.0 2.4 2 0 0 2 2 2 2 XPG N-terminal domain XPG_I_2 PF12813.7 CAM36646.1 - 0.03 13.8 0.3 0.057 12.9 0.3 1.3 1 0 0 1 1 1 0 XPG domain containing FA_hydroxylase PF04116.13 CAM36649.1 - 1.9e-22 80.0 17.8 1.9e-22 80.0 17.8 2.3 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily DHC_N1 PF08385.12 CAM36650.1 - 2.7e-153 511.6 0.0 2.7e-153 511.6 0.0 4.0 3 2 0 3 3 2 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 CAM36650.1 - 2.8e-147 489.9 0.0 1e-146 488.1 0.0 2.1 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CAM36650.1 - 4.4e-113 378.4 11.7 4.4e-113 378.4 11.7 4.5 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 CAM36650.1 - 1.1e-97 326.5 2.2 1.1e-97 326.4 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CAM36650.1 - 1.1e-83 281.0 0.1 5.2e-83 278.8 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 CAM36650.1 - 3.3e-80 268.4 0.8 3.3e-80 268.4 0.8 3.0 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 CAM36650.1 - 5.5e-64 215.0 0.4 1.1e-58 197.7 0.0 4.3 5 0 0 5 5 5 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CAM36650.1 - 8e-53 178.6 0.1 1.9e-52 177.4 0.1 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CAM36650.1 - 2.4e-43 147.0 0.0 5e-42 142.8 0.0 3.3 4 0 0 4 4 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 CAM36650.1 - 5.9e-40 137.3 14.4 1.4e-39 136.1 14.4 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 CAM36650.1 - 1.7e-24 86.4 0.2 1.2e-07 31.8 0.0 6.2 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 CAM36650.1 - 3.8e-23 82.0 0.0 1.6e-22 79.9 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CAM36650.1 - 1.4e-16 60.5 0.1 6.3e-16 58.4 0.1 2.2 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CAM36650.1 - 6.4e-07 29.9 1.0 0.85 10.0 0.0 5.9 4 0 0 4 4 4 1 AAA ATPase domain T2SSE PF00437.20 CAM36650.1 - 3.2e-06 26.4 0.0 0.67 9.0 0.0 4.3 4 0 0 4 4 4 2 Type II/IV secretion system protein AAA PF00004.29 CAM36650.1 - 6.1e-05 23.4 0.0 0.48 10.9 0.0 4.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CAM36650.1 - 0.0039 17.5 10.1 2.4 8.4 0.0 6.6 6 0 0 6 6 6 1 AAA domain ABC_tran PF00005.27 CAM36650.1 - 0.029 14.9 0.9 13 6.3 0.0 4.5 4 0 0 4 4 4 0 ABC transporter FtsK_SpoIIIE PF01580.18 CAM36650.1 - 0.058 12.7 0.1 11 5.3 0.0 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family Mg_chelatase PF01078.21 CAM36650.1 - 0.15 11.4 0.1 3.5 6.9 0.0 2.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CAM36650.1 - 0.16 12.4 0.0 55 4.2 0.0 3.5 3 0 0 3 3 3 0 RNA helicase AAA_18 PF13238.6 CAM36650.1 - 0.22 12.0 2.8 3.5 8.2 0.0 4.3 5 0 0 5 5 3 0 AAA domain AAA_24 PF13479.6 CAM36650.1 - 3.6 7.2 4.7 35 4.0 0.0 4.3 5 0 0 5 5 5 0 AAA domain YceI PF04264.13 CAM36651.1 - 6.9e-05 23.4 0.0 7.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 YceI-like domain DNA_pol_B PF00136.21 CAM36652.2 - 4.7e-79 266.2 0.0 6.3e-79 265.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CAM36652.2 - 3.3e-05 23.2 0.0 0.035 13.2 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 CAM36652.2 - 0.0039 17.6 3.1 0.0056 17.1 0.6 2.5 3 0 0 3 3 3 1 C4-type zinc-finger of DNA polymerase delta Radical_SAM_C PF16199.5 CAM36654.1 - 6.7e-16 58.1 0.2 1.3e-15 57.1 0.2 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 CAM36654.1 - 1.2e-14 55.0 0.0 3.4e-14 53.6 0.0 1.8 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 CAM36654.1 - 1.2e-07 32.0 0.2 2.9e-07 30.7 0.2 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CAM36654.1 - 0.00022 21.2 0.1 0.00062 19.7 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Hum_adeno_E3A PF05393.11 CAM36655.1 - 0.059 13.3 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein Mito_carr PF00153.27 CAM36656.2 - 9.8e-37 124.8 0.4 6.6e-16 58.0 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Helicase_C PF00271.31 CAM36657.1 - 7.6e-12 45.6 0.0 4.1e-10 40.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CAM36657.1 - 8.1e-10 38.7 0.0 2e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase HHH_5 PF14520.6 CAM36657.1 - 0.0086 16.7 0.0 0.02 15.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain RTA1 PF04479.13 CAM36658.1 - 0.002 17.7 0.8 0.0027 17.4 0.5 1.3 1 1 0 1 1 1 1 RTA1 like protein MtrD PF04207.12 CAM36658.1 - 0.08 12.6 0.1 0.12 12.1 0.1 1.3 1 1 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit D Mog1 PF04603.12 CAM36659.1 - 1.2e-29 103.4 0.0 1.5e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Fer2_3 PF13085.6 CAM36660.1 - 8.4e-31 106.2 0.1 3e-30 104.4 0.0 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 CAM36660.1 - 0.0039 17.1 0.7 0.013 15.4 0.7 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain LUC7 PF03194.15 CAM36660.1 - 0.026 14.2 0.1 0.039 13.6 0.1 1.2 1 0 0 1 1 1 0 LUC7 N_terminus DHHC PF01529.20 CAM36661.1 - 2.1e-31 108.8 13.8 2.1e-31 108.8 13.8 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase DHHC PF01529.20 CAM36662.2 - 1.9e-32 112.2 3.6 1.9e-32 112.2 3.6 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase zf-AD PF07776.15 CAM36662.2 - 0.16 12.2 3.9 0.45 10.8 3.9 1.7 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) HemY_N PF07219.13 CAM36662.2 - 0.36 11.1 2.7 23 5.2 0.0 3.0 2 0 0 2 2 2 0 HemY protein N-terminus TMIE PF16038.5 CAM36662.2 - 7.8 6.4 7.3 1 9.2 0.7 2.3 2 0 0 2 2 2 0 TMIE protein DHHC PF01529.20 CAM36663.2 - 5.7e-24 84.7 18.4 5.7e-24 84.7 18.4 2.7 2 1 1 3 3 3 3 DHHC palmitoyltransferase PTPlike_phytase PF14566.6 CAM36664.1 - 5.7e-121 400.1 0.6 2.9e-45 154.2 0.0 3.5 3 0 0 3 3 3 3 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 CAM36664.1 - 0.049 13.6 0.5 5.2 7.0 0.0 3.5 4 0 0 4 4 4 0 Tyrosine phosphatase family ADK PF00406.22 CAM36665.1 - 4.2e-07 30.2 0.1 0.00033 20.8 0.0 2.8 3 0 0 3 3 3 2 Adenylate kinase AAA_17 PF13207.6 CAM36665.1 - 0.0014 19.1 0.0 0.72 10.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 CAM36665.1 - 0.02 14.2 0.1 0.052 12.8 0.1 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 CAM36665.1 - 0.023 15.2 0.0 0.076 13.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CAM36665.1 - 0.026 14.7 0.1 0.063 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CAM36665.1 - 0.043 14.2 0.1 0.25 11.8 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Phe_hydrox_dim PF07976.12 CAM36665.1 - 0.071 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Phenol hydroxylase, C-terminal dimerisation domain DUF3619 PF12279.8 CAM36665.1 - 0.098 13.0 1.2 4.3 7.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) AAA_25 PF13481.6 CAM36665.1 - 0.11 12.0 0.1 0.27 10.8 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CAM36665.1 - 0.14 12.1 0.0 0.32 11.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CAM36665.1 - 0.2 12.1 1.9 0.42 11.0 0.3 2.5 1 1 1 2 2 2 0 AAA ATPase domain Methyltransf_25 PF13649.6 CAM36666.1 - 0.11 13.2 0.1 17 6.2 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 CAM36666.1 - 0.16 11.8 0.0 0.27 11.0 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain MtrF PF09472.10 CAM36668.2 - 0.2 11.1 0.1 0.42 10.0 0.1 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Anoctamin PF04547.12 CAM36669.1 - 0.11 11.4 0.2 0.11 11.3 0.2 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel Pet100 PF09803.9 CAM36669.1 - 1.8 9.1 6.8 8.1 7.0 6.8 1.9 1 1 0 1 1 1 0 Pet100 zf-rbx1 PF12678.7 CAM36670.1 - 5.8e-13 48.9 6.4 1.2e-12 47.9 6.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CAM36670.1 - 2.6e-10 40.5 7.9 6.7e-09 35.9 5.0 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CAM36670.1 - 3.4e-07 30.0 8.9 3.7e-06 26.7 5.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CAM36670.1 - 1.6e-06 28.1 1.2 3e-06 27.2 1.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 CAM36670.1 - 4.3e-06 26.6 4.8 1.1e-05 25.3 4.8 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CAM36670.1 - 5.3e-06 26.2 7.2 1.2e-05 25.1 7.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CAM36670.1 - 6.4e-05 22.9 2.1 6.4e-05 22.9 2.1 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 CAM36670.1 - 0.001 18.8 1.1 0.001 18.8 1.1 2.9 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 CAM36670.1 - 0.0018 18.1 8.3 0.0066 16.3 3.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CAM36670.1 - 0.0028 17.5 7.6 0.0099 15.7 3.5 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 CAM36670.1 - 0.023 14.3 4.8 0.032 13.8 2.6 2.1 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 CAM36670.1 - 0.26 11.2 4.1 0.22 11.4 2.5 1.7 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-P11 PF03854.14 CAM36670.1 - 0.44 10.2 4.1 0.42 10.3 2.5 1.8 2 0 0 2 2 2 0 P-11 zinc finger FANCL_C PF11793.8 CAM36670.1 - 0.68 10.2 8.5 7.6 6.8 8.5 2.5 1 1 1 2 2 2 0 FANCL C-terminal domain RINGv PF12906.7 CAM36670.1 - 2.5 8.3 8.9 0.69 10.1 5.1 1.9 2 0 0 2 2 2 0 RING-variant domain V-SNARE PF05008.15 CAM36671.1 - 1.3e-10 41.4 0.5 5.5e-08 33.1 0.0 3.1 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.13 CAM36671.1 - 2.9e-06 27.1 2.4 7.6e-06 25.8 0.2 2.3 2 1 0 2 2 2 1 Sec20 V-SNARE_C PF12352.8 CAM36671.1 - 7.8e-06 26.1 1.9 7.8e-06 26.1 1.9 1.7 2 0 0 2 2 1 1 Snare region anchored in the vesicle membrane C-terminus Nup54 PF13874.6 CAM36671.1 - 0.0018 18.4 0.9 0.0018 18.4 0.9 2.0 1 1 1 2 2 2 1 Nucleoporin complex subunit 54 Laminin_I PF06008.14 CAM36671.1 - 0.0043 16.8 4.0 0.011 15.5 0.5 2.4 1 1 1 3 3 3 1 Laminin Domain I Vps51 PF08700.11 CAM36671.1 - 0.019 15.0 1.6 4.8 7.3 0.0 3.9 4 1 1 5 5 5 0 Vps51/Vps67 DUF4618 PF15397.6 CAM36671.1 - 0.034 13.6 2.3 0.83 9.0 0.5 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) Uds1 PF15456.6 CAM36671.1 - 0.039 14.1 8.2 0.7 10.1 3.1 2.3 2 0 0 2 2 2 0 Up-regulated During Septation Syntaxin-6_N PF09177.11 CAM36671.1 - 0.049 14.2 3.7 0.29 11.7 0.2 3.0 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Fez1 PF06818.15 CAM36671.1 - 0.31 11.5 5.1 0.95 9.9 4.0 2.0 1 1 1 2 2 2 0 Fez1 HAUS-augmin3 PF14932.6 CAM36671.1 - 0.75 9.3 7.5 0.48 10.0 0.8 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 FliJ PF02050.16 CAM36671.1 - 3.9 7.7 8.8 1.7 8.9 0.9 2.3 2 0 0 2 2 2 0 Flagellar FliJ protein Lebercilin PF15619.6 CAM36671.1 - 4.6 6.9 8.4 2.3 7.8 0.8 2.8 3 1 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease KASH_CCD PF14662.6 CAM36671.1 - 6.2 6.6 8.6 6 6.6 0.4 3.0 3 1 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH V-SNARE PF05008.15 CAM36672.1 - 4.2e-13 49.5 2.2 2e-12 47.3 0.0 2.8 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 CAM36672.1 - 5.2e-07 29.8 0.9 1.1e-06 28.9 0.9 1.5 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 CAM36672.1 - 7.5e-06 25.8 1.9 1.3e-05 25.0 1.2 1.8 2 0 0 2 2 2 1 Sec20 Unstab_antitox PF09720.10 CAM36672.1 - 0.0045 17.0 1.3 0.03 14.4 0.0 2.7 3 0 0 3 3 3 1 Putative addiction module component DUF745 PF05335.13 CAM36672.1 - 0.0066 16.2 5.7 0.28 10.9 2.4 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF745) KASH_CCD PF14662.6 CAM36672.1 - 0.0078 16.1 5.4 0.56 10.0 1.1 2.2 2 0 0 2 2 2 2 Coiled-coil region of CCDC155 or KASH Synaptobrevin PF00957.21 CAM36672.1 - 0.0082 15.9 1.4 0.022 14.6 1.4 1.8 1 0 0 1 1 1 1 Synaptobrevin TraG_N PF07916.11 CAM36672.1 - 0.058 12.3 0.1 0.074 11.9 0.1 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Baculo_F PF12259.8 CAM36672.1 - 0.078 11.5 0.8 0.19 10.2 0.1 1.7 2 0 0 2 2 2 0 Baculovirus F protein Spore_III_AB PF09548.10 CAM36672.1 - 0.15 12.2 3.0 0.35 11.0 0.1 2.3 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Spc7 PF08317.11 CAM36672.1 - 0.16 10.8 4.3 0.27 10.1 4.3 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein CSN5_C PF18323.1 CAM36672.1 - 0.51 11.3 5.3 0.15 13.0 1.4 2.0 2 1 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain Fez1 PF06818.15 CAM36672.1 - 0.92 9.9 4.8 1.5 9.2 0.6 2.2 1 1 0 2 2 2 0 Fez1 DUF883 PF05957.13 CAM36672.1 - 1.3 9.7 13.9 1.7 9.3 1.7 3.2 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) RTT107_BRCT_5 PF16770.5 CAM36673.1 - 0.2 11.6 0.0 0.42 10.5 0.0 1.5 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain EXOSC1 PF10447.9 CAM36674.1 - 0.00064 20.3 0.0 0.032 14.8 0.0 2.3 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 VEGFR-2_TMD PF17988.1 CAM36675.2 - 6.5 6.3 9.5 3.2 7.2 6.5 2.1 1 1 1 2 2 2 0 VEGFR-2 Transmembrane domain TPH PF13868.6 CAM36676.1 - 9.8e-34 116.4 127.8 9.8e-34 116.4 127.8 2.1 2 0 0 2 2 2 1 Trichohyalin-plectin-homology domain TIP41 PF04176.13 CAM36677.1 - 7.5e-22 77.6 0.0 1.2e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 TIP41-like family GAF_2 PF13185.6 CAM36677.1 - 2.5e-10 40.8 0.0 6.1e-10 39.5 0.0 1.7 2 0 0 2 2 2 1 GAF domain GAF PF01590.26 CAM36677.1 - 4.8e-07 30.5 0.0 1e-06 29.4 0.0 1.6 1 0 0 1 1 1 1 GAF domain LRR_4 PF12799.7 CAM36678.1 - 2e-05 24.8 5.6 0.0014 19.0 0.1 3.1 1 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CAM36678.1 - 0.0058 16.1 0.2 0.0087 15.6 0.2 1.3 1 0 0 1 1 1 1 Leucine-rich repeat CDC45 PF02724.14 CAM36678.1 - 0.032 12.5 6.9 0.036 12.4 6.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2183 PF09949.9 CAM36678.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) LRR_6 PF13516.6 CAM36678.1 - 0.37 11.0 3.0 5.9 7.2 0.0 3.4 4 0 0 4 4 4 0 Leucine Rich repeat Nop14 PF04147.12 CAM36678.1 - 4.7 5.3 10.2 5.2 5.2 10.2 1.1 1 0 0 1 1 1 0 Nop14-like family Ala_racemase_N PF01168.20 CAM36679.1 - 5.4e-20 72.0 0.0 6.2e-20 71.8 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain LRR_8 PF13855.6 CAM36680.1 - 3.7e-08 33.0 3.4 0.1 12.4 0.2 5.3 4 2 0 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 CAM36680.1 - 1.5e-06 27.9 2.1 4.6 8.2 0.1 5.4 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_4 PF12799.7 CAM36680.1 - 2.3e-05 24.6 6.4 0.36 11.3 0.6 4.8 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CAM36680.1 - 0.00059 19.7 5.1 0.53 10.5 0.7 3.6 3 0 0 3 3 3 2 Leucine Rich repeat DUF1618 PF07762.14 CAM36681.1 - 1 10.0 5.1 0.57 10.8 0.4 2.6 2 1 0 3 3 3 0 Protein of unknown function (DUF1618) V_ATPase_I PF01496.19 CAM36682.1 - 1e-260 867.2 22.1 5.5e-177 590.2 0.6 3.0 1 1 2 3 3 3 3 V-type ATPase 116kDa subunit family DUF3021 PF11457.8 CAM36682.1 - 0.0093 16.3 3.5 0.0093 16.3 3.5 3.3 3 1 0 3 3 3 1 Protein of unknown function (DUF3021) Osmo_CC PF08946.10 CAM36682.1 - 0.79 10.0 3.0 0.98 9.7 1.2 2.1 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Atg14 PF10186.9 CAM36682.1 - 1.1 8.3 2.8 4.7 6.2 2.8 1.9 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UbiA PF01040.18 CAM36683.1 - 2.6e-49 167.8 22.4 3.5e-49 167.4 22.4 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family NRDE-2 PF08424.10 CAM36686.2 - 1.1e-05 24.8 3.1 0.03 13.4 0.1 4.3 3 1 1 4 4 4 3 NRDE-2, necessary for RNA interference TPR_19 PF14559.6 CAM36686.2 - 0.059 13.9 6.3 17 6.0 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 CAM36686.2 - 1.2 9.3 5.9 4.3 7.6 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 CAM36686.2 - 1.5 9.9 25.9 8.8 7.4 0.0 8.9 8 2 2 10 10 10 0 Tetratricopeptide repeat Beach PF02138.18 CAM36688.1 - 1.1e-87 294.0 0.0 1.4e-87 293.6 0.0 1.1 1 0 0 1 1 1 1 Beige/BEACH domain HBM PF16591.5 CAM36688.1 - 0.012 15.0 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 Helical bimodular sensor domain Nuc_deoxyrib_tr PF05014.15 CAM36689.1 - 2.7e-37 127.7 0.0 3.2e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase Nuc_deoxyri_tr2 PF15891.5 CAM36689.1 - 0.014 15.7 0.0 0.02 15.2 0.0 1.3 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase like DUF4406 PF14359.6 CAM36689.1 - 0.031 14.8 0.0 0.047 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4406) Nuc_deoxyri_tr3 PF11071.8 CAM36689.1 - 0.076 13.1 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase YtoQ CENP-T_C PF15511.6 CAM36690.1 - 2.1e-06 27.8 0.1 3.5e-06 27.1 0.1 1.4 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CAM36690.1 - 0.00019 21.7 0.3 0.00051 20.3 0.0 1.8 2 1 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 CAM36690.1 - 0.00067 19.8 0.1 0.0012 19.0 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 CAM36690.1 - 0.0036 17.7 2.0 0.0083 16.5 2.0 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 CAM36690.1 - 0.0041 17.1 0.0 0.0062 16.5 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 CAM36690.1 - 0.081 13.0 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit LRR_6 PF13516.6 CAM36691.1 - 0.00095 19.0 6.2 4.1 7.7 0.2 4.5 4 0 0 4 4 4 3 Leucine Rich repeat Ank_2 PF12796.7 CAM36692.1 - 2.5e-45 153.0 13.5 2e-11 44.3 0.1 11.5 10 3 3 13 13 13 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CAM36692.1 - 1.4e-35 121.2 19.2 2.8e-05 24.6 0.0 13.5 13 2 2 15 15 15 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 CAM36692.1 - 8.5e-32 105.6 23.9 0.0023 18.3 0.0 16.3 17 1 0 17 17 17 7 Ankyrin repeat Ank_5 PF13857.6 CAM36692.1 - 4.9e-29 100.0 15.3 0.00021 21.5 0.0 12.2 11 1 1 12 12 12 6 Ankyrin repeats (many copies) Ank PF00023.30 CAM36692.1 - 1.4e-22 79.0 28.1 0.00011 22.5 0.0 16.1 16 0 0 16 16 16 5 Ankyrin repeat Gas_vesicle PF00741.18 CAM36692.1 - 0.091 12.9 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Gas vesicle protein Kinesin PF00225.23 CAM36693.1 - 4.9e-88 295.2 0.1 9.3e-88 294.3 0.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CAM36693.1 - 6.3e-21 74.9 0.1 1.7e-17 63.7 0.0 3.2 3 0 0 3 3 3 2 Microtubule binding ubiquitin PF00240.23 CAM36694.1 - 0.00065 19.4 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family CAF20 PF17052.5 CAM36694.1 - 1.3 9.1 6.7 2.7 8.1 6.7 1.4 1 0 0 1 1 1 0 Cap associated factor NST1 PF13945.6 CAM36694.1 - 4.9 7.2 8.3 10 6.2 8.3 1.5 1 0 0 1 1 1 0 Salt tolerance down-regulator Surp PF01805.20 CAM36695.1 - 4.1e-09 36.3 0.0 8e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Surp module COG4 PF08318.12 CAM36696.2 - 1.3e-44 152.6 0.0 3.6e-44 151.2 0.0 1.7 2 0 0 2 2 2 1 COG4 transport protein RINT1_TIP1 PF04437.13 CAM36696.2 - 1.8e-05 23.9 0.6 3.2e-05 23.0 0.1 1.7 2 0 0 2 2 2 1 RINT-1 / TIP-1 family Sec10 PF07393.11 CAM36696.2 - 0.0056 15.2 0.7 0.049 12.1 0.1 2.2 2 0 0 2 2 2 1 Exocyst complex component Sec10 DEAD PF00270.29 CAM36697.1 - 7.3e-33 113.8 0.1 1.5e-16 60.6 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CAM36697.1 - 1.5e-20 73.6 0.1 9.6e-20 71.0 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAM36697.1 - 0.00019 21.5 0.0 0.00061 19.8 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit FCP1_C PF09309.10 CAM36697.1 - 0.093 12.6 5.1 0.19 11.6 5.1 1.4 1 0 0 1 1 1 0 FCP1, C-terminal CDC45 PF02724.14 CAM36697.1 - 2.1 6.6 4.9 3.5 5.8 4.9 1.2 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 CAM36697.1 - 5.1 7.5 11.6 0.42 11.0 5.7 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GATase_6 PF13522.6 CAM36698.1 - 0.082 13.1 0.2 0.6 10.3 0.1 2.1 2 0 0 2 2 2 0 Glutamine amidotransferase domain DUF1263 PF06882.12 CAM36701.1 - 0.041 13.9 0.2 0.13 12.3 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1263) Pkinase PF00069.25 CAM36702.2 - 3e-58 197.2 0.0 5.1e-58 196.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM36702.2 - 1.1e-35 123.2 0.0 1.8e-35 122.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM36702.2 - 1.4e-06 27.8 0.0 0.00061 19.2 0.0 2.3 2 0 0 2 2 2 2 Kinase-like PAS PF00989.25 CAM36702.2 - 2.8e-06 27.3 0.0 8.8e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 PAS fold Pkinase_fungal PF17667.1 CAM36702.2 - 4.5e-06 25.7 0.0 8.7e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase PAS_4 PF08448.10 CAM36702.2 - 4.8e-06 26.8 0.0 2.2e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 PAS fold Kdo PF06293.14 CAM36702.2 - 7.6e-05 22.2 0.0 0.00045 19.6 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_9 PF13426.7 CAM36702.2 - 0.00029 21.0 0.0 0.0012 19.0 0.0 2.1 2 0 0 2 2 2 1 PAS domain PAS_10 PF13596.6 CAM36702.2 - 0.0066 17.0 0.0 0.026 15.1 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 CAM36702.2 - 0.018 15.1 0.0 0.064 13.3 0.0 1.9 1 0 0 1 1 1 0 PAS domain FTA2 PF13095.6 CAM36702.2 - 0.036 13.7 0.0 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CAM36702.2 - 0.094 12.6 0.0 0.25 11.2 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family FA_desaturase PF00487.24 CAM36705.1 - 2.4e-21 76.7 25.2 3.4e-21 76.2 25.2 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 CAM36705.1 - 8.4e-18 63.6 1.2 1.6e-17 62.7 1.2 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) LRR_4 PF12799.7 CAM36739.1 - 2.2e-56 186.8 0.0 0.0013 19.1 0.1 15.9 11 4 3 15 15 15 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM36739.1 - 1.2e-06 28.1 11.6 3.2 7.6 0.3 8.5 8 2 1 9 9 9 3 Leucine rich repeat LRR_9 PF14580.6 CAM36739.1 - 2.4e-06 27.2 4.3 0.23 11.0 0.0 7.0 4 4 4 9 9 9 2 Leucine-rich repeat LRR_5 PF13306.6 CAM36739.1 - 6e-06 26.2 2.7 3.9 7.5 0.0 6.3 5 2 2 7 7 7 2 BspA type Leucine rich repeat region (6 copies) 2-Hacid_dh_C PF02826.19 CAM36741.1 - 2.5e-54 183.4 0.1 3.6e-54 182.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CAM36741.1 - 6.8e-35 119.7 0.1 9.2e-35 119.2 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CAM36741.1 - 9.6e-06 25.8 0.5 2e-05 24.8 0.5 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 CAM36741.1 - 0.0047 16.5 0.2 0.0094 15.5 0.2 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 CAM36741.1 - 0.016 15.3 0.7 0.03 14.4 0.7 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 CAM36741.1 - 0.023 15.2 0.0 0.065 13.7 0.0 1.8 2 0 0 2 2 2 0 XdhC Rossmann domain Aminotran_5 PF00266.19 CAM36742.2 - 4.8e-24 85.0 0.0 6.4e-24 84.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Met_10 PF02475.16 CAM36743.1 - 2.2e-41 141.8 0.0 1.1e-37 129.7 0.0 2.1 2 0 0 2 2 2 2 Met-10+ like-protein MTS PF05175.14 CAM36743.1 - 0.00012 21.7 0.0 0.0002 20.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 CAM36743.1 - 0.00038 20.1 0.0 0.00058 19.5 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 CAM36743.1 - 0.01 16.5 0.0 0.031 15.0 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 CAM36743.1 - 0.012 15.4 0.0 0.046 13.5 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 CAM36743.1 - 0.082 11.9 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase MyTH4 PF00784.17 CAM36744.1 - 0.051 14.1 0.0 0.15 12.6 0.0 1.8 1 0 0 1 1 1 0 MyTH4 domain Acyltransferase PF01553.21 CAM36745.2 - 3.8e-12 46.0 0.0 1.4e-11 44.2 0.0 2.0 1 1 0 1 1 1 1 Acyltransferase zf_UBZ PF18439.1 CAM36745.2 - 0.0021 17.6 1.5 0.0043 16.6 1.5 1.5 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger ATP-synt_D PF01813.17 CAM36745.2 - 0.025 14.4 0.3 0.053 13.4 0.3 1.4 1 0 0 1 1 1 0 ATP synthase subunit D PrgI PF12666.7 CAM36745.2 - 0.52 11.0 7.5 2.3 9.0 0.4 2.7 2 0 0 2 2 2 0 PrgI family protein DNA_primase_lrg PF04104.14 CAM36746.2 - 1.7e-81 273.6 0.0 2.2e-81 273.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit CtaG_Cox11 PF04442.14 CAM36747.1 - 4.4e-47 159.9 0.2 5.8e-47 159.5 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 RNase_H2-Ydr279 PF09468.10 CAM36748.2 - 0.061 13.5 0.8 0.16 12.2 0.8 1.7 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain YlqD PF11068.8 CAM36748.2 - 8.4 6.8 13.1 17 5.8 0.1 3.5 3 0 0 3 3 3 0 YlqD protein LRR_4 PF12799.7 CAM36749.2 - 1.7e-10 41.0 14.5 0.0012 19.2 0.4 4.4 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CAM36749.2 - 2.1e-09 37.1 4.3 8.4e-05 22.1 0.1 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 CAM36749.2 - 3.9e-08 32.9 15.5 0.0014 18.4 1.7 4.0 4 0 0 4 4 4 3 Leucine rich repeat TMF_TATA_bd PF12325.8 CAM36749.2 - 0.0074 16.5 10.0 0.015 15.5 10.0 1.5 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Dynactin_p62 PF05502.13 CAM36749.2 - 0.02 13.7 1.0 0.034 13.0 1.0 1.3 1 0 0 1 1 1 0 Dynactin p62 family LRR_6 PF13516.6 CAM36749.2 - 0.039 14.0 7.2 1.4 9.1 0.1 4.7 4 1 1 5 5 5 0 Leucine Rich repeat DUF4530 PF15039.6 CAM36749.2 - 0.048 13.8 2.5 0.069 13.3 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4530) Tup_N PF08581.10 CAM36749.2 - 0.057 13.7 6.7 2.7 8.4 0.9 2.7 2 0 0 2 2 2 0 Tup N-terminal Spc7 PF08317.11 CAM36749.2 - 0.09 11.6 8.5 0.15 10.9 8.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ATG16 PF08614.11 CAM36749.2 - 2.2 8.4 17.3 10 6.3 12.9 2.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Prefoldin_2 PF01920.20 CAM36749.2 - 2.3 8.2 6.3 1.3 9.1 1.2 2.4 1 1 1 2 2 2 0 Prefoldin subunit Filament PF00038.21 CAM36749.2 - 2.5 7.6 14.3 0.69 9.4 11.2 1.7 2 0 0 2 2 2 0 Intermediate filament protein HALZ PF02183.18 CAM36749.2 - 2.5 8.4 8.9 3.3 8.0 0.5 3.3 3 1 0 3 3 3 0 Homeobox associated leucine zipper DUF1640 PF07798.11 CAM36749.2 - 3.4 7.7 9.2 5.8 6.9 9.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) COG2 PF06148.11 CAM36749.2 - 3.6 7.7 4.8 3.9 7.6 3.3 1.8 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 YabA PF06156.13 CAM36749.2 - 7.6 7.2 7.1 1.8 9.3 3.5 1.9 2 0 0 2 2 1 0 Initiation control protein YabA Acetyltransf_1 PF00583.25 CAM36750.1 - 6.3e-08 32.9 0.1 8.5e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CAM36750.1 - 1e-06 28.7 0.1 1.4e-06 28.3 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CAM36750.1 - 3.2e-05 24.2 0.1 4.5e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2606 PF10794.9 CAM36750.1 - 0.067 13.0 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) DUF4558 PF15104.6 CAM36751.1 - 0.0031 17.5 4.6 0.0056 16.7 4.6 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4558) FMN_dh PF01070.18 CAM36751.1 - 0.037 13.1 0.1 0.063 12.3 0.0 1.4 1 1 0 1 1 1 0 FMN-dependent dehydrogenase ABC_tran PF00005.27 CAM36753.1 - 3.4e-47 160.4 5.3 4e-23 82.4 0.0 3.7 4 0 0 4 4 3 2 ABC transporter ABC_tran_Xtn PF12848.7 CAM36753.1 - 1.1e-24 86.3 4.1 1.1e-24 86.3 4.1 3.2 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.6 CAM36753.1 - 1.5e-17 64.4 9.0 0.00042 20.2 0.4 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CAM36753.1 - 1.8e-11 43.9 1.0 0.0039 16.7 0.1 4.3 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CAM36753.1 - 9.9e-09 35.8 0.1 0.0047 17.3 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 CAM36753.1 - 1.1e-07 31.5 0.3 0.0043 16.8 0.0 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 CAM36753.1 - 1.1e-07 32.0 0.3 0.11 12.2 0.0 4.1 3 1 0 4 4 4 2 AAA ATPase domain MMR_HSR1 PF01926.23 CAM36753.1 - 1.4e-07 31.6 0.1 0.0085 16.2 0.1 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CAM36753.1 - 2e-07 31.1 0.4 0.0016 18.4 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 CAM36753.1 - 2.5e-05 24.6 5.0 0.016 15.5 0.0 3.4 4 0 0 4 4 3 2 AAA domain AAA_23 PF13476.6 CAM36753.1 - 7.9e-05 23.3 12.2 0.029 14.9 0.0 4.2 5 0 0 5 5 4 2 AAA domain AAA_22 PF13401.6 CAM36753.1 - 7.9e-05 23.0 1.2 0.28 11.4 0.1 3.3 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.6 CAM36753.1 - 0.00011 22.4 3.9 0.44 10.7 0.1 3.6 2 1 0 3 3 3 2 AAA domain AAA_18 PF13238.6 CAM36753.1 - 0.00013 22.5 0.9 0.17 12.4 0.0 3.4 3 0 0 3 3 2 1 AAA domain Roc PF08477.13 CAM36753.1 - 0.00017 21.8 0.0 0.62 10.3 0.0 2.9 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 CAM36753.1 - 0.00018 21.9 0.0 1.4 9.4 0.0 3.5 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CAM36753.1 - 0.00024 20.9 0.2 1.1 9.0 0.0 3.0 2 2 0 2 2 2 2 AAA domain NACHT PF05729.12 CAM36753.1 - 0.00042 20.3 0.1 0.81 9.6 0.0 2.6 2 0 0 2 2 2 2 NACHT domain PduV-EutP PF10662.9 CAM36753.1 - 0.0012 18.7 0.1 0.24 11.1 0.0 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 CAM36753.1 - 0.0012 18.4 0.1 2.1 7.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 CAM36753.1 - 0.0012 18.8 0.0 1.8 8.6 0.0 3.5 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.23 CAM36753.1 - 0.0027 17.8 0.7 5.7 7.0 0.0 3.7 4 0 0 4 4 3 0 Dynamin family RNA_helicase PF00910.22 CAM36753.1 - 0.0031 17.9 0.0 0.99 9.8 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.14 CAM36753.1 - 0.0034 17.4 0.2 3.2 7.7 0.0 3.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 CAM36753.1 - 0.005 16.0 0.1 1 8.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) FeoB_N PF02421.18 CAM36753.1 - 0.0053 16.3 0.1 0.31 10.5 0.1 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_24 PF13479.6 CAM36753.1 - 0.0053 16.5 3.7 2.7 7.7 0.0 3.6 4 0 0 4 4 3 2 AAA domain AAA_7 PF12775.7 CAM36753.1 - 0.0059 16.1 0.1 0.57 9.7 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 CAM36753.1 - 0.0066 15.8 0.1 1.1 8.4 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin TsaE PF02367.17 CAM36753.1 - 0.0069 16.4 0.1 0.68 10.0 0.0 2.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 CAM36753.1 - 0.0079 15.8 0.2 1.6 8.3 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Ploopntkinase3 PF18751.1 CAM36753.1 - 0.016 15.2 0.1 0.71 9.8 0.0 2.8 2 1 0 2 2 2 0 P-loop Nucleotide Kinase3 SRP54 PF00448.22 CAM36753.1 - 0.016 14.8 0.2 5.4 6.6 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Arf PF00025.21 CAM36753.1 - 0.017 14.6 2.7 2.1 7.8 0.0 3.4 4 0 0 4 4 3 0 ADP-ribosylation factor family AAA_27 PF13514.6 CAM36753.1 - 0.023 14.3 0.9 7.3 6.1 0.0 3.4 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 CAM36753.1 - 0.025 13.8 0.0 8.2 5.5 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 CAM36753.1 - 0.039 13.9 0.4 8.4 6.3 0.1 3.1 3 0 0 3 3 2 0 NTPase Ras PF00071.22 CAM36753.1 - 0.052 13.1 0.1 1.3 8.6 0.0 2.5 2 0 0 2 2 2 0 Ras family Septin PF00735.18 CAM36753.1 - 0.068 12.4 1.9 2.3 7.4 0.0 2.8 3 0 0 3 3 2 0 Septin MeaB PF03308.16 CAM36753.1 - 0.075 12.0 0.1 6 5.8 0.0 2.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase_2 PF01637.18 CAM36753.1 - 0.17 11.8 2.1 11 5.9 0.0 3.2 4 0 0 4 4 3 0 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 CAM36753.1 - 0.32 10.7 1.6 29 4.4 0.0 3.4 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein MobB PF03205.14 CAM36753.1 - 0.81 9.6 3.6 10 6.0 0.1 3.5 3 1 1 4 4 3 0 Molybdopterin guanine dinucleotide synthesis protein B zf-C2H2_3 PF13878.6 CAM36755.1 - 5.2e-13 48.6 0.1 1.2e-12 47.5 0.1 1.7 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO zf-CCCH PF00642.24 CAM36756.1 - 1.6e-07 31.0 8.5 0.00024 20.9 1.0 2.7 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CAM36756.1 - 3.1e-07 30.2 7.3 0.00089 19.2 1.3 2.6 2 0 0 2 2 2 2 Zinc finger domain RRM_1 PF00076.22 CAM36756.1 - 2e-05 24.3 0.0 0.00028 20.6 0.0 2.4 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 CAM36756.1 - 0.0015 19.2 8.9 0.028 15.1 0.3 2.7 2 1 1 3 3 3 2 Torus domain zf-CCCH_3 PF15663.5 CAM36756.1 - 0.51 10.6 6.3 7 6.9 0.4 2.3 2 0 0 2 2 2 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 CAM36756.1 - 0.82 10.2 4.1 33 5.2 0.1 2.8 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 CAM36756.1 - 3.3 7.6 11.5 2 8.3 1.6 2.9 2 2 0 2 2 2 0 CCCH-type zinc finger Aldedh PF00171.22 CAM36757.1 - 2.3e-103 346.2 0.0 2.9e-103 345.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pkinase PF00069.25 CAM36758.1 - 4.5e-58 196.7 0.0 5.8e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM36758.1 - 4e-29 101.7 0.0 7.6e-29 100.8 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAM36758.1 - 6.1e-05 22.0 0.0 9e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CAM36758.1 - 0.00041 19.4 0.1 0.0007 18.6 0.1 1.5 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CAM36758.1 - 0.0027 17.7 1.7 1.7 8.5 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 CAM36758.1 - 0.0029 17.0 0.0 0.0057 16.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CAM36758.1 - 0.027 14.1 0.1 0.058 13.0 0.1 1.5 1 1 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 CAM36758.1 - 0.037 13.3 0.0 0.12 11.6 0.0 2.0 1 1 0 1 1 1 0 Kinase-like AMP-binding PF00501.28 CAM36760.2 - 5.7e-95 318.4 0.2 8.1e-95 317.9 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Ribosomal_L38e PF01781.18 CAM36762.1 - 3.4e-29 100.8 4.4 4e-29 100.5 4.4 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Apolipoprotein PF01442.18 CAM36764.1 - 8.2e-99 329.1 240.8 4.3e-11 43.0 21.5 18.7 2 1 14 16 16 16 14 Apolipoprotein A1/A4/E domain Cep57_CLD_2 PF14197.6 CAM36764.1 - 5.5e-51 170.5 210.9 9.8e-05 22.4 4.7 19.9 5 3 14 19 19 18 15 Centrosome localisation domain of PPC89 DUF3618 PF12277.8 CAM36764.1 - 4.9e-43 145.1 246.1 0.0089 16.3 8.3 18.6 2 2 15 17 17 17 15 Protein of unknown function (DUF3618) Prefoldin_2 PF01920.20 CAM36764.1 - 2.7e-11 43.3 134.4 0.48 10.4 1.1 19.6 5 3 14 19 19 19 14 Prefoldin subunit FYVE PF01363.21 CAM36764.1 - 1.2e-10 41.4 9.3 1.2e-10 41.4 9.3 1.9 2 0 0 2 2 1 1 FYVE zinc finger GAS PF13851.6 CAM36764.1 - 1.1e-07 31.4 155.5 0.011 15.1 17.4 10.2 4 2 7 11 11 11 7 Growth-arrest specific micro-tubule binding Flg_hook PF02120.16 CAM36764.1 - 7e-07 29.0 157.8 1.6 8.7 2.9 17.5 3 2 15 18 18 18 14 Flagellar hook-length control protein FliK APG6_N PF17675.1 CAM36764.1 - 1.3e-05 25.8 213.5 0.041 14.4 22.1 11.9 3 2 12 15 15 15 10 Apg6 coiled-coil region HAUS-augmin3 PF14932.6 CAM36764.1 - 0.00062 19.4 8.7 0.00062 19.4 8.7 11.7 4 2 12 16 16 16 6 HAUS augmin-like complex subunit 3 MscS_porin PF12795.7 CAM36764.1 - 0.0011 18.5 241.7 0.39 10.2 18.5 11.3 4 2 7 11 11 11 8 Mechanosensitive ion channel porin domain Filament PF00038.21 CAM36764.1 - 0.0021 17.7 1.4 0.0021 17.7 1.4 11.3 2 1 6 8 8 8 2 Intermediate filament protein DUF1492 PF07374.11 CAM36764.1 - 0.0068 16.6 51.6 33 4.7 0.1 14.5 3 2 13 16 16 16 0 Protein of unknown function (DUF1492) DUF3552 PF12072.8 CAM36764.1 - 0.012 15.0 0.6 0.012 15.0 0.6 10.0 4 2 8 12 12 5 0 Domain of unknown function (DUF3552) DUF4407 PF14362.6 CAM36764.1 - 0.039 13.3 212.7 0.87 8.9 7.7 9.0 1 1 7 8 8 8 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 CAM36764.1 - 0.29 11.2 79.7 6.2 6.9 1.0 12.1 3 2 14 18 18 18 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.8 CAM36764.1 - 0.64 10.3 153.1 2.4 8.4 9.0 14.0 4 3 15 19 19 19 0 TATA element modulatory factor 1 TATA binding CREPT PF16566.5 CAM36764.1 - 0.81 9.9 125.5 0.34 11.1 4.3 11.5 4 3 6 11 11 10 0 Cell-cycle alteration and expression-elevated protein in tumour zf-RING_9 PF13901.6 CAM36765.2 - 4.1e-07 30.2 22.3 0.021 14.8 0.0 5.6 5 1 0 5 5 5 4 Putative zinc-RING and/or ribbon Jnk-SapK_ap_N PF09744.9 CAM36766.1 - 0.06 13.6 0.1 0.06 13.6 0.1 2.5 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF2857 PF11198.8 CAM36766.1 - 0.083 12.7 10.4 0.35 10.6 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2857) DUF1664 PF07889.12 CAM36766.1 - 0.13 12.3 0.3 0.26 11.3 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3867 PF12983.7 CAM36767.1 - 0.069 13.2 4.6 0.29 11.2 1.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3867) TraW_N PF12477.8 CAM36768.1 - 0.2 11.6 2.6 0.4 10.7 0.3 2.8 2 0 0 2 2 2 0 Sex factor F TraW protein N terminal DDRGK PF09756.9 CAM36769.1 - 2.3e-23 82.8 23.7 3.5e-16 59.3 0.0 2.3 2 0 0 2 2 2 2 DDRGK domain Nop53 PF07767.11 CAM36769.1 - 0.91 8.8 28.1 2 7.7 28.1 1.6 1 1 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Pkinase PF00069.25 CAM36770.1 - 8.4e-32 110.6 0.0 9.6e-25 87.4 0.0 3.3 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM36770.1 - 9.3e-14 51.3 0.0 3.8e-12 46.0 0.0 2.9 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM36770.1 - 0.0019 17.6 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Gpr1_Fun34_YaaH PF01184.19 CAM36771.1 - 1.1e-46 159.1 14.2 1.3e-46 158.8 14.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Gpr1_Fun34_YaaH PF01184.19 CAM36772.1 - 3e-46 157.6 16.1 4e-46 157.2 16.1 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family MFS_1 PF07690.16 CAM36773.1 - 5.1e-28 98.0 13.5 1.6e-17 63.5 0.1 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 CAM36773.1 - 3.7e-08 32.1 0.0 1.7e-05 23.4 0.0 3.1 3 1 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 CAM36773.1 - 5e-08 31.9 19.3 0.00027 19.6 6.0 3.6 2 2 1 4 4 4 2 MFS/sugar transport protein T2SSM PF04612.12 CAM36773.1 - 0.0033 17.5 0.2 0.0033 17.5 0.2 2.2 3 0 0 3 3 3 1 Type II secretion system (T2SS), protein M DUF2730 PF10805.8 CAM36773.1 - 0.83 9.8 2.8 1.2 9.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) DUF4131 PF13567.6 CAM36773.1 - 2.8 7.6 8.1 3.7 7.2 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Ribosomal_60s PF00428.19 CAM36775.2 - 2.8e-22 79.1 11.8 3.4e-22 78.8 11.8 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_60s PF00428.19 CAM36776.1 - 6.4e-23 81.2 12.2 7.6e-23 80.9 12.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein TLD PF07534.16 CAM36777.1 - 8.9e-15 55.1 0.0 4.3e-14 52.9 0.0 1.9 2 0 0 2 2 2 1 TLD DUF3439 PF11921.8 CAM36777.1 - 1.2 9.1 5.0 27 4.8 2.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DSPc PF00782.20 CAM36778.1 - 0.032 14.0 0.2 0.077 12.8 0.2 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Neur_chan_memb PF02932.16 CAM36778.1 - 5.3 7.0 9.6 24 4.9 9.6 2.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RRM_1 PF00076.22 CAM36779.1 - 1.1e-12 47.5 0.2 0.00015 21.5 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TruD PF01142.18 CAM36780.1 - 0.00022 20.2 0.0 0.00042 19.3 0.0 1.4 1 0 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) AAA PF00004.29 CAM36781.1 - 1.3e-44 151.8 0.3 2.4e-44 150.9 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAM36781.1 - 8.5e-13 47.9 0.9 1.5e-12 47.1 0.0 1.9 2 0 0 2 2 1 1 AAA+ lid domain AAA_2 PF07724.14 CAM36781.1 - 1.8e-07 31.4 0.0 4.9e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CAM36781.1 - 2.7e-07 31.1 0.0 0.0005 20.5 0.0 2.4 1 1 1 2 2 2 2 AAA ATPase domain Prot_ATP_ID_OB PF16450.5 CAM36781.1 - 3.7e-07 30.0 0.2 8.5e-07 28.8 0.2 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 CAM36781.1 - 1e-06 28.8 0.1 1e-05 25.5 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CAM36781.1 - 4.5e-06 26.5 0.0 1.3e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CAM36781.1 - 6e-05 23.3 0.1 0.022 15.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 CAM36781.1 - 0.00041 19.6 0.0 0.00091 18.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.13 CAM36781.1 - 0.00053 19.3 0.0 0.0011 18.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 CAM36781.1 - 0.0014 18.4 0.0 0.003 17.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 CAM36781.1 - 0.0017 17.8 0.1 0.0034 16.8 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CAM36781.1 - 0.0017 18.7 0.0 0.0053 17.1 0.0 1.9 2 0 0 2 2 1 1 RNA helicase AAA_24 PF13479.6 CAM36781.1 - 0.0021 17.8 0.1 0.0042 16.8 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_7 PF12775.7 CAM36781.1 - 0.0023 17.5 0.0 0.0074 15.8 0.0 1.7 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 CAM36781.1 - 0.0035 17.4 0.0 0.0074 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.17 CAM36781.1 - 0.0055 15.8 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_18 PF13238.6 CAM36781.1 - 0.0056 17.2 0.1 0.021 15.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 CAM36781.1 - 0.011 15.1 3.0 0.098 12.0 0.1 2.8 2 1 1 3 3 3 0 KaiC AAA_25 PF13481.6 CAM36781.1 - 0.013 15.1 0.1 0.1 12.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 CAM36781.1 - 0.019 14.7 0.1 0.062 13.0 0.1 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.11 CAM36781.1 - 0.023 14.6 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CAM36781.1 - 0.023 14.9 0.0 0.051 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 CAM36781.1 - 0.027 13.9 0.2 0.067 12.6 0.2 1.6 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 CAM36781.1 - 0.029 14.9 0.1 0.19 12.2 0.0 2.3 2 0 0 2 2 2 0 ABC transporter ATPase_2 PF01637.18 CAM36781.1 - 0.031 14.2 0.9 1.2 8.9 0.0 2.8 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea TsaE PF02367.17 CAM36781.1 - 0.031 14.3 0.0 0.066 13.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Prot_ATP_OB_N PF17758.1 CAM36781.1 - 0.037 13.7 0.0 0.097 12.3 0.0 1.7 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain AAA_33 PF13671.6 CAM36781.1 - 0.056 13.6 0.1 0.14 12.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_11 PF13086.6 CAM36781.1 - 0.057 13.2 0.3 0.79 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CAM36781.1 - 0.071 12.8 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CAM36781.1 - 0.074 13.0 0.1 0.35 10.8 0.0 2.0 1 1 1 2 2 2 0 NACHT domain AAA_19 PF13245.6 CAM36781.1 - 0.13 12.6 0.2 0.34 11.2 0.2 1.7 1 1 0 1 1 1 0 AAA domain PI3K_1B_p101 PF10486.9 CAM36782.2 - 9.5 3.9 13.7 15 3.2 13.7 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit ADH_zinc_N PF00107.26 CAM36784.1 - 2.9e-19 69.4 0.0 5.8e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CAM36784.1 - 4.5e-16 60.1 0.0 1.1e-15 58.8 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CAM36784.1 - 9.2e-10 38.4 0.0 3.6e-09 36.5 0.0 2.1 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain DEAD_2 PF06733.15 CAM36786.2 - 3.8e-23 82.0 0.8 2.1e-08 34.0 0.0 4.3 4 0 0 4 4 4 4 DEAD_2 DUF3246 PF11596.8 CAM36786.2 - 0.0079 15.7 0.8 0.14 11.5 0.4 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3246) MeaB PF03308.16 CAM36787.1 - 5.4e-74 248.5 0.1 7e-74 248.2 0.1 1.1 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 CAM36787.1 - 8.4e-08 32.0 0.0 2.4e-07 30.5 0.0 1.8 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 CAM36787.1 - 0.0067 16.8 0.1 0.017 15.5 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain ParA PF10609.9 CAM36787.1 - 0.0081 15.6 0.4 1.1 8.7 0.1 2.2 2 0 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase AAA_29 PF13555.6 CAM36787.1 - 0.02 14.6 0.0 0.047 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 CAM36787.1 - 0.028 14.7 0.3 0.28 11.4 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.7 CAM36787.1 - 0.084 11.8 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain SMC_N PF02463.19 CAM36787.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Dis3l2_C_term PF17877.1 CAM36791.1 - 0.051 13.9 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal TPT PF03151.16 CAM36791.1 - 0.22 10.8 6.6 0.021 14.2 1.7 1.8 3 0 0 3 3 3 0 Triose-phosphate Transporter family DUF5470 PF17564.2 CAM36791.1 - 9.6 6.5 6.6 36 4.6 6.6 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5470) CRT-like PF08627.10 CAM36792.1 - 1.4 7.8 10.7 0.17 10.8 2.5 2.6 2 1 1 3 3 3 0 CRT-like, chloroquine-resistance transporter-like AAA_16 PF13191.6 CAM36793.1 - 0.0057 17.0 0.2 0.015 15.7 0.1 1.7 2 0 0 2 2 2 1 AAA ATPase domain RecA PF00154.21 CAM36793.1 - 0.026 14.0 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein AAA_14 PF13173.6 CAM36793.1 - 0.027 14.5 0.0 0.071 13.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain HEM4 PF02602.15 CAM36794.1 - 3e-56 190.4 0.4 3.5e-56 190.2 0.4 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD DUF1467 PF07330.12 CAM36794.1 - 0.059 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1467) DEAD PF00270.29 CAM36795.1 - 3.4e-20 72.5 0.0 1e-18 67.7 0.0 2.9 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.15 CAM36795.1 - 7.6e-09 35.8 0.0 1.8e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CAM36795.1 - 6.1e-05 23.3 0.1 0.00018 21.8 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Beta_helix PF13229.6 CAM36796.1 - 0.00021 21.2 2.9 19 5.1 0.0 6.1 7 1 0 7 7 7 2 Right handed beta helix region CxC4 PF18717.1 CAM36796.1 - 0.13 12.1 0.2 0.5 10.2 0.2 2.0 1 0 0 1 1 1 0 CxC4 like cysteine cluster associated with KDZ transposases tRNA_edit PF04073.15 CAM36797.2 - 5.3e-20 71.7 0.1 2.3e-19 69.7 0.1 1.9 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain bact-PGI_C PF10432.9 CAM36797.2 - 0.1 12.6 0.7 0.27 11.3 0.2 1.9 2 0 0 2 2 2 0 Bacterial phospho-glucose isomerase C-terminal SIS domain COX17 PF05051.13 CAM36800.1 - 4.7e-15 55.7 7.4 6.1e-15 55.3 7.4 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) TatD_DNase PF01026.21 CAM36801.2 - 9.1e-50 169.4 0.4 4.1e-49 167.3 0.4 2.1 1 1 0 1 1 1 1 TatD related DNase Bromo_MP PF01573.16 CAM36802.1 - 0.016 14.6 0.0 0.019 14.3 0.0 1.0 1 0 0 1 1 1 0 Bromovirus movement protein LRR_4 PF12799.7 CAM36803.1 - 2.7e-12 46.7 6.6 0.00014 22.1 0.0 3.8 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) Ubiquitin_2 PF14560.6 CAM36803.1 - 3.2e-10 40.3 0.0 6e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain LRR_9 PF14580.6 CAM36803.1 - 6.5e-10 38.8 3.0 0.0014 18.1 1.3 3.9 3 1 1 4 4 4 3 Leucine-rich repeat LRR_8 PF13855.6 CAM36803.1 - 7.4e-06 25.6 12.6 0.27 11.0 0.1 4.4 2 2 0 3 3 3 3 Leucine rich repeat ubiquitin PF00240.23 CAM36803.1 - 0.00078 19.1 0.2 0.0086 15.8 0.2 2.3 1 1 0 1 1 1 1 Ubiquitin family LRR_6 PF13516.6 CAM36803.1 - 0.0022 17.9 9.3 0.53 10.5 0.1 5.0 4 0 0 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.33 CAM36803.1 - 0.38 11.5 5.6 90 4.2 0.0 4.9 5 0 0 5 5 5 0 Leucine Rich Repeat Pkinase PF00069.25 CAM36804.1 - 1.3e-31 109.9 0.0 4.1e-29 101.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM36804.1 - 3e-12 46.4 0.0 1.5e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAM36804.1 - 0.0044 15.9 0.0 0.0087 14.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CAM36804.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RNA_pol_Rpb4 PF03874.16 CAM36805.2 - 0.058 13.7 0.0 0.24 11.7 0.0 2.0 2 0 0 2 2 2 0 RNA polymerase Rpb4 6PF2K PF01591.18 CAM36806.2 - 6.7e-62 208.7 0.0 1e-61 208.1 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase Ank_2 PF12796.7 CAM36806.2 - 2.8e-12 47.0 0.2 9.8e-12 45.3 0.2 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CAM36806.2 - 1.2e-09 38.5 0.2 4.5e-09 36.7 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CAM36806.2 - 2.9e-08 33.8 1.6 1.7e-07 31.4 0.5 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CAM36806.2 - 6.3e-07 29.6 0.7 0.00058 20.2 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 CAM36806.2 - 5e-06 26.5 0.1 0.064 13.8 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat AAA_33 PF13671.6 CAM36806.2 - 8e-06 26.1 0.6 1.8e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain His_Phos_1 PF00300.22 CAM36806.2 - 0.00013 21.8 0.0 0.062 13.0 0.0 2.7 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) Vir_act_alpha_C PF10400.9 CAM36806.2 - 0.05 14.3 0.4 0.15 12.8 0.4 1.7 1 0 0 1 1 1 0 Virulence activator alpha C-term zf-C6H2 PF15801.5 CAM36811.1 - 4.5e-10 39.7 8.3 9.2e-10 38.7 8.3 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 CAM36811.1 - 0.00025 21.1 6.6 0.00049 20.1 6.6 1.5 1 0 0 1 1 1 1 MYND finger Prok-RING_4 PF14447.6 CAM36811.1 - 0.053 13.4 0.8 0.13 12.2 0.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 LRR_4 PF12799.7 CAM36814.1 - 1.5e-06 28.4 11.1 0.088 13.3 0.0 4.8 3 1 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM36814.1 - 0.00022 20.9 17.5 0.001 18.8 2.2 3.8 2 1 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 CAM36814.1 - 1.4 9.7 6.3 91 4.2 0.0 4.7 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 CAM36814.1 - 7.7 6.9 13.8 49 4.3 0.2 5.7 6 0 0 6 6 6 0 Leucine Rich repeat NIF PF03031.18 CAM36816.1 - 1.2e-25 90.1 0.2 1.9e-18 66.7 0.0 2.6 3 0 0 3 3 3 2 NLI interacting factor-like phosphatase Brix PF04427.18 CAM36817.1 - 1.6e-33 116.4 0.1 2.3e-33 115.9 0.1 1.2 1 0 0 1 1 1 1 Brix domain SLX9 PF15341.6 CAM36817.1 - 7.5 7.0 15.6 3.7 8.0 12.8 1.9 2 1 0 2 2 2 0 Ribosome biogenesis protein SLX9 Pyrophosphatase PF00719.19 CAM36818.1 - 1.4e-41 142.0 0.0 1.8e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Got1 PF04178.12 CAM36819.1 - 4.8e-28 97.9 21.1 7e-28 97.3 21.1 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family IBV_3C PF03620.13 CAM36819.1 - 0.055 13.9 1.6 0.12 12.9 1.6 1.6 1 0 0 1 1 1 0 IBV 3C protein ECF_trnsprt PF12822.7 CAM36819.1 - 3 7.9 13.9 0.84 9.7 2.7 2.2 1 1 0 2 2 2 0 ECF transporter, substrate-specific component Amidohydro_3 PF07969.11 CAM36820.1 - 1.6e-61 209.2 7.2 2.3e-61 208.8 7.2 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 CAM36820.1 - 6.5e-16 58.6 0.4 5.4e-11 42.4 0.1 3.1 3 0 0 3 3 3 2 Amidohydrolase family Cu-oxidase_2 PF07731.14 CAM36822.1 - 1.3e-20 73.5 0.7 1.3e-20 73.5 0.7 3.2 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 CAM36822.1 - 3.9e-10 39.8 4.9 7.3e-07 29.2 1.3 4.0 3 1 0 3 3 3 2 Multicopper oxidase MORN PF02493.20 CAM36824.1 - 3.2e-23 80.2 37.9 4.3e-06 26.3 0.8 7.6 8 1 0 8 8 8 6 MORN repeat Tudor_2 PF18104.1 CAM36824.1 - 0.037 13.7 0.4 3.5 7.4 0.0 3.2 2 1 1 3 3 3 0 Jumonji domain-containing protein 2A Tudor domain EIF_2_alpha PF07541.12 CAM36825.1 - 1.4e-16 60.7 0.0 4.3e-15 55.8 0.0 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 CAM36825.1 - 1.6e-11 44.3 0.5 3.7e-11 43.2 0.5 1.6 1 0 0 1 1 1 1 S1 RNA binding domain EXOSC1 PF10447.9 CAM36825.1 - 0.031 14.9 0.1 0.058 14.0 0.1 1.6 1 1 0 1 1 1 0 Exosome component EXOSC1/CSL4 Ntox35 PF15534.6 CAM36825.1 - 0.081 13.4 0.0 0.5 10.8 0.0 2.1 2 0 0 2 2 2 0 Bacterial toxin 35 LRR_4 PF12799.7 CAM36826.2 - 3.2e-19 68.7 0.0 0.022 15.2 0.0 9.4 6 4 2 10 10 10 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM36826.2 - 0.00025 20.8 6.3 2.6 7.9 0.0 6.4 6 1 0 7 7 7 2 Leucine rich repeat LRR_9 PF14580.6 CAM36826.2 - 0.00098 18.7 1.5 11 5.4 0.0 5.9 3 3 3 6 6 6 1 Leucine-rich repeat LRR_6 PF13516.6 CAM36826.2 - 0.001 19.0 4.4 23 5.4 0.0 7.3 8 0 0 8 8 8 1 Leucine Rich repeat LRR_1 PF00560.33 CAM36826.2 - 0.0076 16.6 7.0 2.1 9.2 0.1 6.7 7 0 0 7 7 7 1 Leucine Rich Repeat Ribosomal_S19e PF01090.19 CAM36828.1 - 7.8e-43 145.5 0.0 9.8e-43 145.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19e Mrr_N PF14338.6 CAM36828.1 - 0.014 15.5 0.0 0.027 14.6 0.0 1.5 1 0 0 1 1 1 0 Mrr N-terminal domain Peptidase_C14 PF00656.22 CAM36833.1 - 0.34 10.8 7.9 2.5e+02 1.4 0.0 9.2 9 4 0 9 9 9 0 Caspase domain Apolipoprotein PF01442.18 CAM36834.1 - 2.9e-129 428.4 275.1 2.4e-07 30.8 4.6 20.8 1 1 19 20 20 20 20 Apolipoprotein A1/A4/E domain Cep57_CLD_2 PF14197.6 CAM36834.1 - 4.6e-65 215.6 254.7 0.00016 21.7 5.6 23.6 4 2 20 24 24 23 19 Centrosome localisation domain of PPC89 DUF3618 PF12277.8 CAM36834.1 - 4.6e-59 196.5 307.9 0.0086 16.3 8.6 21.7 1 1 19 20 20 20 19 Protein of unknown function (DUF3618) Prefoldin_2 PF01920.20 CAM36834.1 - 4.3e-21 74.9 149.7 0.38 10.7 1.1 22.7 3 2 19 22 22 22 18 Prefoldin subunit GAS PF13851.6 CAM36834.1 - 3.9e-14 52.5 177.3 0.027 13.8 13.0 11.4 2 1 14 17 17 17 14 Growth-arrest specific micro-tubule binding Flg_hook PF02120.16 CAM36834.1 - 5.8e-14 51.8 197.9 1.7 8.6 2.9 21.0 2 1 19 21 21 21 19 Flagellar hook-length control protein FliK Seryl_tRNA_N PF02403.22 CAM36834.1 - 2.6e-11 43.7 155.8 0.21 11.8 5.8 13.2 3 1 17 20 20 20 16 Seryl-tRNA synthetase N-terminal domain MscS_porin PF12795.7 CAM36834.1 - 3.9e-09 36.4 280.0 1.2 8.6 20.2 12.5 2 1 13 15 15 15 12 Mechanosensitive ion channel porin domain APG6_N PF17675.1 CAM36834.1 - 3.9e-09 37.1 245.0 0.091 13.3 23.1 12.4 1 1 21 22 22 22 17 Apg6 coiled-coil region CREPT PF16566.5 CAM36834.1 - 1e-06 29.0 143.0 0.38 10.9 4.6 12.8 2 2 19 21 21 20 18 Cell-cycle alteration and expression-elevated protein in tumour TMF_TATA_bd PF12325.8 CAM36834.1 - 5.3e-05 23.4 174.9 1.7 8.9 8.1 15.7 2 2 20 22 22 22 17 TATA element modulatory factor 1 TATA binding HAUS-augmin3 PF14932.6 CAM36834.1 - 0.0001 22.0 194.9 0.0005 19.7 7.2 12.6 2 1 19 21 21 21 3 HAUS augmin-like complex subunit 3 DUF1492 PF07374.11 CAM36834.1 - 0.0003 20.9 68.5 66 3.8 0.1 18.3 2 1 18 20 20 20 0 Protein of unknown function (DUF1492) DivIC PF04977.15 CAM36834.1 - 0.00044 20.0 243.4 0.99 9.2 4.0 24.0 3 2 22 25 25 25 19 Septum formation initiator DUF4407 PF14362.6 CAM36834.1 - 0.00065 19.2 249.6 1.1 8.6 7.8 9.7 1 1 9 10 10 10 1 Domain of unknown function (DUF4407) HAP1_N PF04849.13 CAM36834.1 - 0.005 16.1 171.7 0.66 9.1 12.0 10.4 1 1 12 13 13 13 6 HAP1 N-terminal conserved region DUF1664 PF07889.12 CAM36834.1 - 0.0053 16.8 97.6 4.3 7.4 0.9 14.0 2 1 20 22 22 22 10 Protein of unknown function (DUF1664) KASH_CCD PF14662.6 CAM36834.1 - 0.25 11.1 166.1 0.28 11.0 4.1 8.4 2 1 10 12 12 12 0 Coiled-coil region of CCDC155 or KASH Leu_zip PF15294.6 CAM36834.1 - 0.42 10.1 134.6 4.4 6.7 8.3 10.2 1 1 13 15 15 15 0 Leucine zipper TPR_MLP1_2 PF07926.12 CAM36834.1 - 0.67 10.0 248.9 0.36 10.9 28.2 10.7 2 2 13 15 15 14 0 TPR/MLP1/MLP2-like protein Filament PF00038.21 CAM36834.1 - 0.81 9.2 194.0 0.52 9.8 23.1 13.3 1 1 6 7 7 6 0 Intermediate filament protein DUF5304 PF17230.2 CAM36834.1 - 5.1 7.3 146.5 6.5 7.0 2.5 19.1 2 2 19 21 21 20 0 Family of unknown function (DUF5304) Macoilin PF09726.9 CAM36835.2 - 0.0026 16.4 21.1 0.0026 16.4 21.1 5.6 1 1 5 6 6 6 1 Macoilin family BLOC1_2 PF10046.9 CAM36835.2 - 0.01 16.1 1.8 0.01 16.1 1.8 9.9 5 2 2 9 9 9 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3502 PF12010.8 CAM36835.2 - 0.18 12.4 5.3 0.27 11.9 0.7 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF3502) Arf PF00025.21 CAM36837.1 - 3.9e-54 182.7 0.0 4.4e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CAM36837.1 - 7.8e-09 35.2 0.9 6.5e-06 25.5 0.0 2.8 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 CAM36837.1 - 2.3e-08 33.7 0.0 2.9e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CAM36837.1 - 5.3e-08 32.9 0.0 1.2e-07 31.8 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 CAM36837.1 - 6.2e-08 32.9 0.0 1.8e-07 31.4 0.0 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CAM36837.1 - 2.2e-07 30.6 0.0 2.9e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.27 CAM36837.1 - 2.8e-05 23.8 0.1 0.01 15.4 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CAM36837.1 - 0.00017 21.0 0.0 0.00023 20.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region cobW PF02492.19 CAM36837.1 - 0.011 15.4 0.1 0.81 9.3 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 CAM36837.1 - 0.037 13.6 0.0 0.21 11.1 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B SRP54 PF00448.22 CAM36837.1 - 0.15 11.7 0.2 0.15 11.7 0.2 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ROQ_II PF18386.1 CAM36838.2 - 7.2 6.5 6.7 1.9 8.4 1.9 2.6 2 0 0 2 2 2 0 Roquin II domain DUF1664 PF07889.12 CAM36839.2 - 0.013 15.5 2.2 0.013 15.5 2.2 5.1 5 0 0 5 5 5 0 Protein of unknown function (DUF1664) DUF1878 PF08963.10 CAM36839.2 - 1.5 9.4 9.0 0.06 13.8 0.8 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1878) Baculo_PEP_C PF04513.12 CAM36839.2 - 1.5 8.9 10.3 51 3.9 0.9 4.8 4 2 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Vault PF01505.18 CAM36840.1 - 5.8e-50 167.2 2.0 1.7e-12 47.3 0.0 5.0 4 0 0 4 4 4 4 Major Vault Protein repeat domain MVP_shoulder PF11978.8 CAM36840.1 - 8.2e-47 158.1 0.2 1.6e-46 157.2 0.2 1.5 1 0 0 1 1 1 1 Shoulder domain Vault_3 PF17795.1 CAM36840.1 - 8e-32 109.1 1.7 3.2e-30 104.0 0.1 3.6 3 0 0 3 3 3 1 Major Vault Protein Repeat domain Vault_2 PF17794.1 CAM36840.1 - 2.9e-28 98.0 0.5 5e-21 74.8 0.1 3.4 3 0 0 3 3 3 2 Major Vault Protein repeat domain Vault_4 PF17796.1 CAM36840.1 - 3.8e-21 74.9 0.1 2.1e-19 69.4 0.1 3.2 3 0 0 3 3 3 1 Major Vault Protein repeat domain NfeD PF01957.18 CAM36840.1 - 0.011 16.0 4.0 4.5 7.7 0.0 4.3 4 1 1 5 5 5 0 NfeD-like C-terminal, partner-binding DUF3601 PF12208.8 CAM36840.1 - 0.015 15.4 0.0 4.7 7.4 0.0 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF3601) Dynein_light PF01221.18 CAM36841.1 - 1e-29 102.6 0.6 1.2e-29 102.4 0.6 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Vasohibin PF14822.6 CAM36841.1 - 0.0045 16.3 0.1 0.006 15.8 0.1 1.3 1 1 0 1 1 1 1 Vasohibin CBM_48 PF02922.18 CAM36841.1 - 0.098 13.0 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Rrp15p PF07890.12 CAM36842.1 - 3.8e-10 40.2 12.1 1.1e-09 38.7 12.1 1.7 1 1 0 1 1 1 1 Rrp15p NUDIX PF00293.28 CAM36843.1 - 1.9e-15 57.1 0.0 2.8e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Metallophos PF00149.28 CAM36844.1 - 4.2e-26 92.7 0.1 6.9e-26 92.0 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Plus-3 PF03126.18 CAM36844.1 - 7.9e-06 26.4 0.0 1.5e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Plus-3 domain Methyltransf_4 PF02390.17 CAM36846.1 - 0.0031 17.0 0.0 0.0046 16.4 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Pkinase PF00069.25 CAM36847.1 - 4.3e-54 183.7 0.0 6.6e-54 183.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM36847.1 - 1.4e-28 99.9 0.1 5.6e-26 91.4 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAM36847.1 - 7.1e-06 25.1 0.0 9.1e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CAM36847.1 - 0.0012 18.9 0.0 0.0047 16.9 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 CAM36847.1 - 0.0041 16.7 0.3 0.011 15.2 0.2 1.6 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.22 CAM36847.1 - 0.028 14.0 0.7 0.065 12.8 0.4 1.5 1 1 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 CAM36847.1 - 0.047 12.6 0.3 0.072 12.0 0.3 1.2 1 0 0 1 1 1 0 Haspin like kinase domain 6PGD PF00393.19 CAM36847.1 - 0.095 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 6-phosphogluconate dehydrogenase, C-terminal domain Kinase-PolyVal PF18762.1 CAM36847.1 - 0.13 12.2 0.3 0.29 11.1 0.3 1.6 1 1 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins DEAD PF00270.29 CAM36848.1 - 8.2e-42 142.9 0.0 1.7e-41 141.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAM36848.1 - 1.6e-31 108.9 0.0 2.2e-28 98.8 0.0 3.3 3 0 0 3 3 3 2 Helicase conserved C-terminal domain GUCT PF08152.12 CAM36848.1 - 1.9e-19 69.7 0.0 5.4e-19 68.3 0.0 1.8 1 0 0 1 1 1 1 GUCT (NUC152) domain ERCC3_RAD25_C PF16203.5 CAM36848.1 - 7.6e-05 22.0 0.0 0.00017 20.9 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 CAM36848.1 - 0.017 15.1 0.5 0.054 13.5 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit LRR_6 PF13516.6 CAM36849.1 - 1.5e-39 130.6 20.9 1.4e-06 27.9 0.2 10.6 11 0 0 11 11 11 8 Leucine Rich repeat LRR_4 PF12799.7 CAM36849.1 - 3.1e-09 36.9 5.5 5.8e-05 23.4 0.0 5.0 5 2 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CAM36849.1 - 2.9e-08 33.1 0.0 5.8 7.9 0.0 7.1 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_8 PF13855.6 CAM36849.1 - 1.1e-06 28.3 8.2 0.13 12.1 0.1 5.7 4 2 1 5 5 5 3 Leucine rich repeat IFRD PF05004.13 CAM36849.1 - 0.0028 16.8 0.5 0.004 16.3 0.5 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) FIVAR PF07554.13 CAM36850.1 - 3.3 8.5 15.1 0.53 11.1 1.1 3.7 3 2 1 4 4 4 0 FIVAR domain Spc7 PF08317.11 CAM36850.1 - 9.3 5.0 46.5 0.011 14.7 12.1 3.4 2 1 1 3 3 3 0 Spc7 kinetochore protein 2-oxoacid_dh PF00198.23 CAM36852.2 - 3.1e-78 262.4 0.0 4e-78 262.1 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CAM36852.2 - 3.6e-17 62.0 1.0 7.5e-17 60.9 0.4 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 CAM36852.2 - 3.3e-13 49.7 0.2 8.4e-13 48.4 0.2 1.8 1 0 0 1 1 1 1 e3 binding domain HlyD_3 PF13437.6 CAM36852.2 - 0.083 13.6 0.7 1.1 10.0 0.1 2.8 3 0 0 3 3 3 0 HlyD family secretion protein Fip1 PF05182.13 CAM36853.2 - 1e-17 63.4 0.5 1.6e-17 62.7 0.5 1.3 1 0 0 1 1 1 1 Fip1 motif zf-CCCH PF00642.24 CAM36853.2 - 4e-09 36.2 3.6 7.4e-09 35.3 3.6 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CAM36853.2 - 0.00089 19.0 4.4 0.0016 18.2 4.4 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CAM36853.2 - 0.0012 18.8 6.0 0.0023 17.9 6.0 1.5 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 CAM36853.2 - 0.003 18.3 1.5 0.0059 17.3 1.5 1.4 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 CAM36853.2 - 0.37 11.3 2.6 0.66 10.5 2.6 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger MMR_HSR1 PF01926.23 CAM36854.1 - 4.7e-16 58.9 0.1 6.2e-14 52.1 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CAM36854.1 - 1.5e-06 27.8 0.1 7.4e-06 25.6 0.0 2.1 3 0 0 3 3 3 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CAM36854.1 - 1.9e-05 24.6 0.0 0.095 12.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 CAM36854.1 - 0.00023 20.6 0.0 0.00052 19.4 0.0 1.6 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 CAM36854.1 - 1.8 8.6 4.2 0.93 9.5 0.2 2.5 2 1 0 2 2 2 0 Dynamin family Fe_hyd_lg_C PF02906.14 CAM36856.1 - 1.2e-52 179.0 0.0 4.7e-52 177.1 0.0 1.9 2 0 0 2 2 2 1 Iron only hydrogenase large subunit, C-terminal domain DUF742 PF05331.11 CAM36856.1 - 0.01 15.6 2.9 0.15 11.9 0.3 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF742) Cortexin PF11057.8 CAM36858.1 - 0.06 13.2 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 Cortexin of kidney Ank_3 PF13606.6 CAM36859.1 - 5.7e-05 23.2 0.1 0.00027 21.1 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 CAM36859.1 - 0.00014 22.0 0.0 0.00035 20.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CAM36859.1 - 0.0004 20.9 0.0 0.0014 19.2 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CAM36859.1 - 0.00042 20.8 0.1 0.0016 19.0 0.1 2.1 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 CAM36859.1 - 0.013 16.0 0.1 0.037 14.5 0.1 1.8 1 0 0 1 1 1 0 Ankyrin repeat K_channel_TID PF07941.11 CAM36860.1 - 0.14 12.7 2.6 0.28 11.7 2.6 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain PTPLA PF04387.14 CAM36861.1 - 1.7e-57 193.7 6.1 2.2e-57 193.4 6.1 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA P16-Arc PF04699.14 CAM36862.1 - 0.00017 22.1 0.0 0.0003 21.3 0.0 1.3 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Mito_carr PF00153.27 CAM36863.1 - 4e-40 135.6 8.2 3.6e-14 52.4 0.0 4.1 4 1 0 4 4 4 3 Mitochondrial carrier protein Glutaredoxin PF00462.24 CAM36865.1 - 9.7e-14 51.3 0.0 1.4e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin MCM PF00493.23 CAM36866.1 - 3.5e-70 235.6 0.0 5.1e-70 235.1 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 CAM36866.1 - 2.8e-15 56.5 0.2 2.1e-09 37.7 0.3 2.5 2 0 0 2 2 2 2 MCM AAA-lid domain MCM_OB PF17207.3 CAM36866.1 - 1.1e-09 38.2 0.3 1.5e-08 34.5 0.0 2.4 2 0 0 2 2 2 1 MCM OB domain AAA_5 PF07728.14 CAM36866.1 - 2.8e-09 37.1 0.0 8.2e-09 35.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CAM36866.1 - 0.00015 21.2 0.2 0.096 12.1 0.0 2.6 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CAM36866.1 - 0.00029 20.7 0.0 0.0007 19.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CAM36866.1 - 0.011 15.4 0.1 0.044 13.5 0.1 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.29 CAM36866.1 - 0.029 14.8 0.0 0.067 13.6 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CAM36866.1 - 0.049 14.0 0.4 0.17 12.3 0.1 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_2 PF07724.14 CAM36866.1 - 0.21 11.7 0.0 0.45 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Ribosomal_S11 PF00411.19 CAM36867.1 - 0.00036 20.9 1.3 0.00057 20.3 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S11 SUIM_assoc PF16619.5 CAM36867.1 - 0.72 10.0 3.7 9.5 6.4 2.4 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DSPc PF00782.20 CAM36868.1 - 2.5e-32 111.5 0.0 4.4e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CAM36868.1 - 0.00033 20.3 0.0 0.00081 19.0 0.0 1.7 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 CAM36868.1 - 0.0094 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Init_tRNA_PT PF04179.12 CAM36868.1 - 0.055 13.8 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 Rit1 DUSP-like domain Pyr_redox_2 PF07992.14 CAM36869.1 - 7.8e-63 212.4 0.1 1.2e-62 211.9 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CAM36869.1 - 1.5e-25 89.6 0.1 2.6e-25 88.8 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CAM36869.1 - 9e-20 71.0 0.0 4.9e-16 59.1 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CAM36869.1 - 5.4e-13 48.9 0.1 1.5e-10 40.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CAM36869.1 - 2.6e-05 23.1 0.8 0.19 10.4 0.0 2.6 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_2 PF00890.24 CAM36869.1 - 0.0001 21.5 1.4 0.0067 15.6 1.0 2.9 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 CAM36869.1 - 0.017 14.3 0.2 0.037 13.3 0.2 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 CAM36869.1 - 0.1 12.6 0.0 0.28 11.2 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 CAM36869.1 - 0.15 11.1 3.5 0.11 11.5 1.6 1.8 2 1 0 2 2 2 0 Glucose inhibited division protein A DEAD PF00270.29 CAM36870.2 - 9.4e-42 142.7 0.0 1.7e-41 141.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAM36870.2 - 2.7e-24 85.7 0.0 6.9e-24 84.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAM36870.2 - 2e-05 24.7 0.0 4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CAM36870.2 - 0.0053 17.0 0.8 0.012 15.9 0.1 2.0 2 1 0 2 2 2 1 AAA domain DUF1143 PF06608.11 CAM36871.2 - 0.15 12.1 0.0 0.46 10.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1143) Pkinase PF00069.25 CAM36874.1 - 7.8e-69 232.0 0.0 9.8e-69 231.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM36874.1 - 2.8e-50 171.0 0.0 4.2e-50 170.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase MORN PF02493.20 CAM36874.1 - 1.3e-38 128.6 50.6 9.4e-10 37.8 3.6 9.0 9 0 0 9 9 9 8 MORN repeat Pkinase_fungal PF17667.1 CAM36874.1 - 0.00012 21.0 0.0 0.00019 20.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CAM36874.1 - 0.0032 16.5 0.0 0.0049 15.9 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CAM36874.1 - 0.0057 16.0 0.0 0.05 12.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 CAM36874.1 - 0.1 12.2 0.0 0.43 10.2 0.0 1.8 1 1 0 2 2 2 0 RIO1 family SMC_N PF02463.19 CAM36875.1 - 1.5e-58 197.8 0.0 2.6e-58 197.0 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CAM36875.1 - 4.1e-11 43.2 5.4 8.8e-05 22.5 0.2 3.1 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CAM36875.1 - 6.1e-10 39.9 17.3 6.1e-10 39.9 17.3 6.1 2 2 3 5 5 5 1 AAA domain SMC_hinge PF06470.13 CAM36875.1 - 1.1e-07 32.2 0.2 1.4e-06 28.6 0.1 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 CAM36875.1 - 9.8e-07 28.8 19.0 0.0046 16.7 14.8 3.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 CAM36875.1 - 9e-05 22.1 0.0 0.00024 20.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3800 PF12686.7 CAM36875.1 - 0.0024 18.5 0.8 0.67 10.6 0.0 4.0 2 1 0 2 2 2 1 Protein of unknown function (DUF3800) SAM_adeno_trans PF01887.16 CAM36875.1 - 0.12 11.8 0.1 0.34 10.3 0.1 1.8 1 0 0 1 1 1 0 S-adenosyl-l-methionine hydroxide adenosyltransferase ABC_tran PF00005.27 CAM36875.1 - 0.31 11.6 22.6 0.76 10.3 4.9 5.6 3 2 0 3 3 3 0 ABC transporter TPR_2 PF07719.17 CAM36876.1 - 5.7e-25 85.4 19.5 0.00051 19.9 0.1 10.0 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_1 PF00515.28 CAM36876.1 - 3.8e-19 67.6 3.4 0.053 13.4 0.1 8.6 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 CAM36876.1 - 1.2e-16 60.0 36.8 0.00018 22.0 0.3 10.5 7 1 5 12 12 9 6 Tetratricopeptide repeat TPR_16 PF13432.6 CAM36876.1 - 9.6e-14 51.8 37.7 4.7e-05 23.9 2.0 8.2 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 CAM36876.1 - 1.3e-12 47.8 31.6 0.00049 20.3 0.3 9.1 5 2 4 9 9 9 4 Tetratricopeptide repeat TPR_17 PF13431.6 CAM36876.1 - 5.8e-11 42.0 2.6 0.00047 20.4 0.0 7.6 8 1 0 8 8 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 CAM36876.1 - 3.1e-10 40.4 30.7 4.2e-05 24.0 0.4 8.5 7 2 1 9 9 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CAM36876.1 - 9.3e-10 38.6 23.5 0.0091 16.2 0.3 6.2 5 1 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CAM36876.1 - 3e-09 36.3 0.2 0.17 12.2 0.2 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 CAM36876.1 - 9.6e-09 35.3 14.3 3.1e-05 24.0 0.9 5.7 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 CAM36876.1 - 1.3e-07 31.2 1.2 1.1 9.0 0.0 6.2 4 1 2 6 6 6 2 TPR repeat TPR_7 PF13176.6 CAM36876.1 - 2.8e-05 23.8 2.7 3.9 7.7 0.1 6.2 6 1 0 6 6 6 1 Tetratricopeptide repeat BTAD PF03704.17 CAM36876.1 - 0.00013 22.4 1.3 0.00013 22.4 1.3 4.5 3 1 1 4 4 4 1 Bacterial transcriptional activator domain TPR_6 PF13174.6 CAM36876.1 - 0.00027 21.4 16.0 0.82 10.4 0.0 8.4 9 0 0 9 9 9 1 Tetratricopeptide repeat NARP1 PF12569.8 CAM36876.1 - 0.0011 18.0 0.6 1.1 8.1 0.0 2.3 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 CAM36876.1 - 0.0023 17.2 14.5 0.02 14.1 0.2 4.1 3 2 1 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CAM36876.1 - 0.021 14.9 1.6 1.1 9.4 0.2 3.5 3 1 1 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat Paf67 PF10255.9 CAM36876.1 - 0.12 11.3 0.2 0.24 10.3 0.2 1.4 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 TPR_4 PF07721.14 CAM36876.1 - 0.37 11.6 14.4 5.1 8.0 0.3 5.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Tctex-1 PF03645.13 CAM36877.1 - 1.5e-23 83.0 1.0 1.6e-23 82.8 1.0 1.0 1 0 0 1 1 1 1 Tctex-1 family Metallophos PF00149.28 CAM36878.2 - 0.0024 18.4 0.2 0.079 13.4 0.0 2.6 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase NGP1NT PF08153.12 CAM36881.2 - 4.5e-43 146.5 0.4 4.5e-43 146.5 0.4 1.9 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 CAM36881.2 - 5.8e-18 65.0 2.4 9.8e-15 54.6 0.1 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CAM36881.2 - 1.2e-05 24.9 0.1 8.7e-05 22.1 0.1 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 CAM36881.2 - 0.0013 18.3 0.0 0.32 10.5 0.0 3.4 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CAM36881.2 - 0.0017 18.3 0.0 0.04 13.8 0.0 2.6 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 CAM36881.2 - 0.0076 16.3 7.8 1.6 8.8 0.0 4.4 3 2 1 4 4 4 2 Dynamin family AAA_16 PF13191.6 CAM36881.2 - 0.02 15.3 0.1 0.12 12.7 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Cas_CT1975 PF09344.10 CAM36881.2 - 0.19 11.2 7.8 0.41 10.1 7.8 1.6 1 0 0 1 1 1 0 CT1975-like protein CCDC53 PF10152.9 CAM36882.1 - 0.0071 16.8 0.6 0.01 16.2 0.2 1.5 1 1 0 1 1 1 1 Subunit CCDC53 of WASH complex VIR_N PF15912.5 CAM36882.1 - 0.16 11.6 5.3 0.2 11.2 5.3 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal MFS_1 PF07690.16 CAM36883.1 - 1.1e-29 103.4 34.1 6.5e-21 74.7 10.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP-synt_ab PF00006.25 CAM36885.1 - 1.2e-14 54.5 0.1 2.2e-14 53.6 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 CAM36885.1 - 5.9e-10 39.6 0.6 1e-08 35.6 0.0 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain His_kinase PF06580.13 CAM36885.1 - 0.22 11.9 5.4 0.32 11.4 0.7 2.4 1 1 1 2 2 2 0 Histidine kinase ATP-synt_ab PF00006.25 CAM36886.1 - 1e-66 224.7 0.1 1.6e-66 224.0 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 CAM36886.1 - 7.3e-09 36.0 0.6 4.9e-08 33.3 0.0 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain His_kinase PF06580.13 CAM36886.1 - 1.1 9.6 4.5 1.1 9.6 0.4 2.4 1 1 1 2 2 2 0 Histidine kinase ADH_zinc_N PF00107.26 CAM36887.1 - 1.1e-06 28.7 0.6 2.1e-06 27.7 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase tRNA_m1G_MT PF01746.21 CAM36887.1 - 0.12 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 tRNA (Guanine-1)-methyltransferase LSM PF01423.22 CAM36889.1 - 0.0011 18.6 0.2 0.0064 16.2 0.2 2.0 1 1 0 1 1 1 1 LSM domain Pkinase PF00069.25 CAM36890.1 - 3.5e-67 226.6 0.0 4e-67 226.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM36890.1 - 2.3e-31 109.1 0.0 3e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CAM36890.1 - 0.00081 18.8 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CAM36890.1 - 0.0037 17.2 0.2 0.059 13.3 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CAM36890.1 - 0.019 13.9 0.0 0.025 13.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 CAM36890.1 - 0.083 11.7 0.0 0.21 10.3 0.0 1.5 1 1 1 2 2 2 0 Fungal protein kinase Choline_kinase PF01633.20 CAM36890.1 - 0.14 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Motile_Sperm PF00635.26 CAM36891.1 - 0.00076 19.3 0.0 0.0051 16.6 0.0 2.1 2 0 0 2 2 2 1 MSP (Major sperm protein) domain Surfac_D-trimer PF09006.11 CAM36893.1 - 0.93 9.4 4.4 5.1 7.1 0.2 3.1 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation Fcf2 PF08698.11 CAM36894.1 - 1.1e-07 32.1 6.3 7.8e-07 29.4 6.3 2.3 1 1 0 1 1 1 1 Fcf2 pre-rRNA processing SAPS PF04499.15 CAM36894.1 - 0.061 12.1 1.6 0.071 11.9 1.6 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1308 PF07000.11 CAM36896.1 - 4.2e-21 75.6 0.0 3e-20 72.8 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1308) DUF89 PF01937.19 CAM36896.1 - 0.14 11.1 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF89 NDUF_B5 PF09781.9 CAM36897.2 - 0.047 13.3 0.6 0.081 12.5 0.6 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit FKBP_N PF01346.18 CAM36898.2 - 0.14 13.2 1.1 0.3 12.1 0.1 1.9 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Nitroreductase PF00881.24 CAM36899.1 - 4.8e-31 108.1 0.0 6.4e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 CAM36899.1 - 0.011 15.3 0.0 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 Putative TM nitroreductase Orbi_NS3 PF01616.16 CAM36900.2 - 0.041 13.6 0.6 0.085 12.5 0.6 1.5 1 0 0 1 1 1 0 Orbivirus NS3 Mtc PF03820.17 CAM36901.1 - 3e-91 305.7 1.2 3.4e-91 305.5 1.2 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier SHIPPO-rpt PF07004.12 CAM36902.1 - 7.2e-71 232.1 195.2 0.0023 18.8 0.6 41.6 43 0 0 43 43 43 38 Sperm-tail PG-rich repeat DSPc PF00782.20 CAM36904.1 - 3.3e-17 62.5 0.0 4.2e-06 26.6 0.1 3.4 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Vta1 PF04652.16 CAM36906.1 - 5e-34 117.3 1.1 8.8e-34 116.6 1.1 1.4 1 0 0 1 1 1 1 Vta1 like Vta1_C PF18097.1 CAM36906.1 - 2.2e-14 52.9 2.6 2.2e-14 52.9 2.6 2.0 2 0 0 2 2 2 1 Vta1 C-terminal domain TFIIA PF03153.13 CAM36906.1 - 3.2 7.6 15.7 4.2 7.3 15.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Wyosine_form PF08608.12 CAM36907.1 - 1.8e-20 73.0 0.6 1.1e-14 54.5 0.0 2.7 2 0 0 2 2 2 2 Wyosine base formation Radical_SAM PF04055.21 CAM36907.1 - 5.2e-20 72.5 0.0 9.8e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 CAM36907.1 - 1.1e-12 48.3 0.0 9.7e-12 45.3 0.0 2.3 2 0 0 2 2 2 1 Flavodoxin MSP1_C PF07462.11 CAM36907.1 - 0.26 10.0 1.8 0.38 9.4 1.8 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Kinesin PF00225.23 CAM36908.2 - 4.1e-80 269.2 0.0 1e-52 179.2 0.0 2.3 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 CAM36908.2 - 6.4e-11 42.4 0.0 3.1e-09 36.9 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding Cortex-I_coil PF09304.10 CAM36908.2 - 0.011 15.9 0.0 0.028 14.6 0.0 1.7 1 0 0 1 1 1 0 Cortexillin I, coiled coil AAA_16 PF13191.6 CAM36908.2 - 0.34 11.3 2.8 0.41 11.0 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain MAM33 PF02330.16 CAM36911.1 - 9.8e-15 55.1 0.0 1.6e-14 54.4 0.0 1.5 1 1 0 1 1 1 1 Mitochondrial glycoprotein zf-MYND PF01753.18 CAM36912.1 - 3.3e-11 43.1 13.5 6.8e-11 42.1 13.5 1.6 1 0 0 1 1 1 1 MYND finger RNA_pol_Rpc4 PF05132.14 CAM36912.1 - 0.056 13.9 0.0 0.51 10.8 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase III RPC4 PNP_UDP_1 PF01048.20 CAM36914.1 - 3.8e-39 134.3 0.3 5e-39 133.9 0.3 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily LPD23 PF18838.1 CAM36915.2 - 0.16 11.7 0.6 0.56 10.0 0.6 1.9 1 0 0 1 1 1 0 Large polyvalent protein associated domain 23 zf-C2HC_2 PF13913.6 CAM36916.1 - 5e-13 48.6 10.1 1.7e-07 31.0 1.5 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-CpG_bind_C PF12269.8 CAM36916.1 - 0.005 16.6 0.4 0.95 9.2 0.0 2.4 2 0 0 2 2 2 2 CpG binding protein zinc finger C terminal domain zf-C2H2_4 PF13894.6 CAM36916.1 - 0.0093 16.7 1.0 5.1 8.2 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CAM36916.1 - 0.067 13.7 0.8 15 6.3 0.1 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zinc_ribbon_9 PF14369.6 CAM36916.1 - 3.6 7.9 5.2 0.5 10.7 0.2 2.1 2 0 0 2 2 2 0 zinc-ribbon SUIM_assoc PF16619.5 CAM36918.2 - 0.021 14.9 10.4 0.14 12.2 5.7 4.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 MMS1_N PF10433.9 CAM36920.1 - 4e-36 124.7 0.0 2.9e-20 72.4 0.0 4.2 3 1 0 3 3 3 3 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 CAM36920.1 - 1.5e-15 57.3 0.0 1.2e-11 44.6 0.0 3.0 3 0 0 3 3 3 2 CPSF A subunit region DUF4228 PF14009.6 CAM36920.1 - 2.2 8.7 7.5 2.3 8.6 3.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4228) DNA_pol_phi PF04931.13 CAM36920.1 - 8.2 4.4 4.9 14 3.6 4.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi LRR_8 PF13855.6 CAM36921.1 - 1.7e-07 30.9 5.1 0.00025 20.7 1.0 2.1 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 CAM36921.1 - 0.017 15.5 1.1 0.1 13.0 0.4 2.4 1 1 0 2 2 2 0 Leucine Rich repeats (2 copies) DUF3720 PF12517.8 CAM36922.2 - 5.2 8.1 9.4 3.1 8.8 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3720) Cyclin PF08613.11 CAM36923.2 - 6.5e-19 68.9 0.0 6.5e-19 68.9 0.0 3.5 5 1 1 6 6 6 1 Cyclin Cyclin_N PF00134.23 CAM36923.2 - 0.0051 16.5 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Flagellar_rod PF05149.12 CAM36924.1 - 1.3e-86 290.6 21.6 1.3e-86 290.6 21.6 2.2 3 0 0 3 3 3 1 Paraflagellar rod protein UQ_con PF00179.26 CAM36925.1 - 1.3e-10 41.1 0.0 3.1e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Peptidase_C98 PF15499.6 CAM36925.1 - 0.075 12.5 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase NUP50 PF08911.11 CAM36926.2 - 0.02 15.5 0.2 0.17 12.5 0.2 2.8 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) DUF2520 PF10728.9 CAM36926.2 - 1.8 8.3 5.5 0.48 10.2 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2520) Peptidase_M28 PF04389.17 CAM36927.2 - 6.3e-16 58.6 1.4 1.2e-05 25.1 0.0 3.4 3 0 0 3 3 3 3 Peptidase family M28 Peptidase_M49 PF03571.15 CAM36928.1 - 2.8e-217 722.5 0.0 3.5e-217 722.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 Cache_3-Cache_2 PF17201.4 CAM36928.1 - 0.025 13.9 0.4 0.046 13.0 0.1 1.5 2 0 0 2 2 2 0 Cache 3/Cache 2 fusion domain COG4 PF08318.12 CAM36928.1 - 0.073 12.1 0.1 1.1 8.3 0.0 2.0 2 0 0 2 2 2 0 COG4 transport protein RVT_1 PF00078.27 CAM36930.1 - 0.0003 20.4 0.0 0.00037 20.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1930 PF09122.10 CAM36931.1 - 6.2e-35 119.0 0.1 1.1e-34 118.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1930) Rhodanese PF00581.20 CAM36931.1 - 3.4e-13 50.0 0.0 6.2e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain Complex1_51K PF01512.17 CAM36932.1 - 9.6e-45 152.2 0.0 1.9e-44 151.2 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 CAM36932.1 - 5.2e-29 100.1 0.0 1.2e-28 99.0 0.0 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 CAM36932.1 - 2.9e-07 30.2 0.0 5.2e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 SLBB domain Ribosomal_S26e PF01283.19 CAM36932.1 - 0.13 12.7 0.1 0.67 10.4 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein S26e NDUF_B7 PF05676.13 CAM36933.1 - 0.032 13.9 0.5 0.044 13.5 0.5 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) zf-C2HC5 PF06221.13 CAM36934.1 - 0.0012 18.8 5.6 0.0012 18.8 5.6 1.9 2 1 0 2 2 2 1 Putative zinc finger motif, C2HC5-type zf-C3HC4_3 PF13920.6 CAM36934.1 - 0.0013 18.6 7.4 0.0023 17.7 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CAM36934.1 - 0.034 14.1 7.1 0.06 13.3 7.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain UPF0506 PF11703.8 CAM36934.1 - 1.2 9.6 8.6 0.45 10.9 5.0 2.1 2 1 0 2 2 2 0 UPF0506 zf-RING_2 PF13639.6 CAM36934.1 - 1.5 9.3 8.8 3 8.3 8.8 1.6 1 0 0 1 1 1 0 Ring finger domain UPF0020 PF01170.18 CAM36935.1 - 3.5e-12 46.4 0.0 3.7e-11 43.1 0.0 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 CAM36935.1 - 0.0019 17.5 0.0 0.014 14.7 0.0 2.1 2 0 0 2 2 2 1 N-6 DNA Methylase N6_N4_Mtase PF01555.18 CAM36935.1 - 0.0061 16.3 0.0 0.081 12.6 0.0 2.3 2 0 0 2 2 2 1 DNA methylase SR-25 PF10500.9 CAM36935.1 - 0.08 12.6 7.3 0.14 11.7 7.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Methyltransf_25 PF13649.6 CAM36935.1 - 0.15 12.8 0.0 0.41 11.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Band_7 PF01145.25 CAM36938.2 - 3.8e-25 88.9 0.0 7.5e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 CAM36938.2 - 2.9e-23 81.7 3.1 2.5e-22 78.7 0.7 2.4 2 0 0 2 2 2 1 C-terminal region of band_7 Band_7_1 PF13421.6 CAM36938.2 - 0.013 15.2 0.1 0.026 14.2 0.1 1.5 1 0 0 1 1 1 0 SPFH domain-Band 7 family FBPase PF00316.20 CAM36939.1 - 0.048 13.1 0.0 0.092 12.2 0.0 1.4 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain AFG1_ATPase PF03969.16 CAM36940.1 - 1.3e-82 277.6 1.4 1.2e-75 254.7 0.1 3.2 3 0 0 3 3 3 3 AFG1-like ATPase AAA_22 PF13401.6 CAM36940.1 - 0.0034 17.7 0.0 0.0065 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.18 CAM36940.1 - 0.041 13.7 0.8 0.25 11.1 0.0 2.4 2 1 0 3 3 3 0 Bacterial dnaA protein Lectin_leg-like PF03388.13 CAM36941.1 - 1.5e-11 44.1 0.0 4.5e-07 29.4 0.0 3.0 2 1 1 3 3 3 2 Legume-like lectin family DMAP1 PF05499.12 CAM36941.1 - 0.021 14.7 0.3 0.043 13.7 0.3 1.4 1 0 0 1 1 1 0 DNA methyltransferase 1-associated protein 1 (DMAP1) MORN PF02493.20 CAM36942.2 - 7.1e-23 79.1 37.0 9e-08 31.6 1.8 7.0 6 0 0 6 6 6 5 MORN repeat GCD14 PF08704.10 CAM36942.2 - 0.17 11.6 0.2 0.4 10.3 0.2 1.5 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Rad21_Rec8_N PF04825.13 CAM36943.2 - 2.5e-28 98.4 0.1 4.8e-28 97.5 0.1 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 CAM36943.2 - 1.8e-07 30.3 0.2 2.3e-06 26.8 0.0 2.4 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein CNDH2_C PF16858.5 CAM36943.2 - 0.12 12.2 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term SMC_ScpA PF02616.14 CAM36943.2 - 0.14 12.0 0.1 18 5.1 0.1 2.2 2 0 0 2 2 2 0 Segregation and condensation protein ScpA Methyltransf_31 PF13847.6 CAM36944.1 - 1.8e-09 37.6 0.0 2.3e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAM36944.1 - 2e-08 34.8 0.0 7e-08 33.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAM36944.1 - 5.3e-08 33.4 0.0 2.9e-07 31.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAM36944.1 - 4.4e-06 27.4 0.0 9.6e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 CAM36944.1 - 2.6e-05 24.0 0.0 0.00061 19.5 0.0 2.2 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) NodS PF05401.11 CAM36944.1 - 3.6e-05 23.5 0.0 7.3e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_8 PF05148.15 CAM36944.1 - 0.00017 21.5 0.0 0.13 12.1 0.0 2.1 2 0 0 2 2 2 2 Hypothetical methyltransferase Pox_MCEL PF03291.16 CAM36944.1 - 0.0072 15.5 0.0 0.026 13.6 0.0 1.8 1 1 0 1 1 1 1 mRNA capping enzyme MTS PF05175.14 CAM36944.1 - 0.0082 15.7 0.0 0.036 13.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_32 PF13679.6 CAM36944.1 - 0.0093 16.0 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CAM36944.1 - 0.012 14.9 0.0 0.025 13.9 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase EutQ PF06249.12 CAM36944.1 - 0.05 13.4 0.0 0.1 12.4 0.0 1.5 1 1 0 1 1 1 0 Ethanolamine utilisation protein EutQ RNA_pol_Rpb1_2 PF00623.20 CAM36945.1 - 3.3e-17 63.2 0.0 7e-17 62.2 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 HCR PF07111.12 CAM36945.1 - 0.093 10.8 0.3 0.12 10.4 0.3 1.0 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) RRM_1 PF00076.22 CAM36946.1 - 1.9e-08 34.0 0.0 0.041 13.7 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) vATP-synt_AC39 PF01992.16 CAM36948.1 - 1.5e-87 294.3 0.7 1.6e-87 294.1 0.7 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit LRR_4 PF12799.7 CAM36949.1 - 4.1e-10 39.8 5.5 0.019 15.4 0.1 6.0 5 1 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM36949.1 - 1.2e-07 31.3 7.3 0.67 9.8 0.0 5.9 6 0 0 6 6 6 3 Leucine rich repeat LRR_6 PF13516.6 CAM36949.1 - 2.2e-05 24.1 5.1 2 8.7 0.1 5.5 5 0 0 5 5 5 1 Leucine Rich repeat LRR_1 PF00560.33 CAM36949.1 - 7.8e-05 22.7 6.0 2.4 9.1 0.0 5.6 6 0 0 6 6 6 2 Leucine Rich Repeat ERM PF00769.19 CAM36949.1 - 0.17 11.7 11.3 0.3 10.8 11.3 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF641 PF04859.12 CAM36949.1 - 0.88 9.9 6.1 1.9 8.8 6.1 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Spc7 PF08317.11 CAM36949.1 - 1.4 7.7 5.4 2.3 7.0 5.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein CCDC92 PF14916.6 CAM36949.1 - 1.5 8.7 3.7 8.3 6.3 0.9 2.4 2 0 0 2 2 2 0 Coiled-coil domain of unknown function ELO PF01151.18 CAM36950.1 - 1.4e-41 142.7 33.4 2.8e-41 141.7 33.4 1.4 1 1 0 1 1 1 1 GNS1/SUR4 family NDUFA12 PF05071.16 CAM36951.1 - 0.017 16.0 0.2 0.066 14.1 0.2 2.0 1 0 0 1 1 1 0 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF346 PF03984.13 CAM36951.1 - 0.048 13.4 5.4 0.2 11.4 2.9 2.5 2 0 0 2 2 2 0 Repeat of unknown function (DUF346) JAKMIP_CC3 PF16034.5 CAM36952.1 - 0.0026 17.7 3.9 0.0026 17.7 3.9 3.0 3 0 0 3 3 3 1 JAKMIP CC3 domain ATP-synt_F6 PF05511.11 CAM36952.1 - 0.061 13.7 0.0 0.4 11.1 0.0 2.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 MetOD1 PF18546.1 CAM36952.1 - 0.1 12.6 0.8 0.34 10.8 0.0 2.1 2 0 0 2 2 2 0 Metanogen output domain 1 Cep57_CLD_2 PF14197.6 CAM36952.1 - 4.3 7.5 8.6 2.7 8.1 4.5 2.9 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Prefoldin_2 PF01920.20 CAM36953.1 - 3.6e-18 65.5 3.8 3.6e-18 65.5 3.8 2.0 1 1 1 2 2 2 1 Prefoldin subunit DHR10 PF18595.1 CAM36953.1 - 0.038 14.0 0.9 0.038 14.0 0.9 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain PCRF PF03462.18 CAM36953.1 - 0.11 12.4 0.1 0.11 12.4 0.1 2.0 1 1 1 2 2 2 0 PCRF domain Ca_chan_IQ PF08763.11 CAM36953.1 - 0.39 11.0 2.5 0.74 10.1 1.2 2.0 2 0 0 2 2 2 0 Voltage gated calcium channel IQ domain kleA_kleC PF17383.2 CAM36953.1 - 0.47 10.8 3.9 0.24 11.7 1.9 1.6 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A DASH_Spc19 PF08287.11 CAM36953.1 - 0.9 9.4 14.2 0.76 9.7 6.1 2.1 1 1 0 2 2 2 0 Spc19 APG6_N PF17675.1 CAM36953.1 - 2.7 8.5 16.3 5 7.7 9.4 2.1 1 1 0 2 2 2 0 Apg6 coiled-coil region FlaC_arch PF05377.11 CAM36953.1 - 3.9 8.0 7.0 29 5.1 1.6 2.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) XhlA PF10779.9 CAM36953.1 - 4.4 7.6 5.6 0.61 10.3 1.1 2.0 3 0 0 3 3 3 0 Haemolysin XhlA YabA PF06156.13 CAM36953.1 - 4.6 7.9 11.1 3.3 8.4 0.6 2.1 1 1 1 2 2 2 0 Initiation control protein YabA LRR_8 PF13855.6 CAM36954.1 - 1.9e-25 88.4 36.8 2e-09 37.0 1.8 6.1 3 2 4 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 CAM36954.1 - 2e-25 88.4 27.1 1.9e-05 24.9 0.2 7.5 3 2 5 9 9 9 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CAM36954.1 - 9.3e-21 74.1 5.3 8.2e-09 35.2 0.1 3.1 2 1 0 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 CAM36954.1 - 1.1e-06 28.2 18.2 1.2 9.3 0.1 8.3 10 0 0 10 10 10 3 Leucine Rich repeat LRR_1 PF00560.33 CAM36954.1 - 0.0042 17.4 21.6 12 6.9 0.1 9.2 9 1 1 10 10 10 1 Leucine Rich Repeat LRR_4 PF12799.7 CAM36955.1 - 0.00041 20.7 0.1 0.028 14.8 0.0 2.9 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM36955.1 - 0.018 14.8 0.0 0.59 9.9 0.0 2.3 2 0 0 2 2 2 0 Leucine rich repeat DUF1848 PF08902.11 CAM36957.1 - 9.1 5.9 7.6 17 5.0 0.3 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1848) RVT_1 PF00078.27 CAM36958.2 - 0.0024 17.4 0.0 0.0056 16.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A17 PF05380.13 CAM36958.2 - 0.0032 17.5 0.1 0.041 13.9 0.0 2.3 1 1 1 2 2 2 1 Pao retrotransposon peptidase ABC2_membrane PF01061.24 CAM36959.2 - 1.8e-38 132.1 15.9 1.8e-38 132.1 15.9 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 CAM36959.2 - 7.2e-22 78.4 0.0 1.1e-21 77.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CAM36959.2 - 0.0002 21.3 0.1 0.1 12.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CAM36959.2 - 0.0011 18.5 0.1 0.026 14.0 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CAM36959.2 - 0.0054 17.1 0.1 0.011 16.1 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 CAM36959.2 - 0.0083 16.0 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase NACHT PF05729.12 CAM36959.2 - 0.012 15.5 0.1 0.024 14.6 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 CAM36959.2 - 0.026 15.0 0.0 0.044 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CAM36959.2 - 0.049 13.4 0.4 0.1 12.4 0.4 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 CAM36959.2 - 0.05 12.7 14.9 0.1 11.7 14.9 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF87 PF01935.17 CAM36959.2 - 0.067 13.3 0.4 0.12 12.5 0.4 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_24 PF13479.6 CAM36959.2 - 0.078 12.7 0.2 0.85 9.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CAM36959.2 - 0.09 13.1 0.0 0.45 10.8 0.0 2.1 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 CAM36959.2 - 0.12 12.4 0.1 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase PRK PF00485.18 CAM36959.2 - 0.21 11.3 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 CAM36959.2 - 0.24 10.6 0.0 0.45 9.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin LRR_4 PF12799.7 CAM36960.1 - 7.6e-23 80.2 0.8 0.0076 16.7 0.1 8.1 6 1 3 9 9 9 8 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CAM36960.1 - 4.1e-08 32.7 21.1 0.0095 15.9 0.0 10.4 12 0 0 12 12 12 3 Leucine Rich repeat LRR_8 PF13855.6 CAM36960.1 - 6.6e-08 32.2 8.8 0.13 12.1 0.0 6.3 4 1 3 7 7 7 3 Leucine rich repeat LRR_9 PF14580.6 CAM36960.1 - 0.021 14.3 5.6 0.4 10.2 0.1 3.7 1 1 2 4 4 4 0 Leucine-rich repeat Neocarzinostat PF00960.18 CAM36960.1 - 0.11 12.5 0.2 1.7 8.7 0.0 2.6 3 0 0 3 3 3 0 Neocarzinostatin family WD40 PF00400.32 CAM36961.2 - 2.8e-53 176.7 29.4 3.8e-10 40.2 0.2 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM36961.2 - 5.7e-08 32.9 0.2 0.0047 17.2 0.1 4.5 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CAM36961.2 - 3.2e-07 30.0 1.9 0.0077 15.6 0.2 3.4 2 2 1 3 3 3 2 WD40-like domain Nup160 PF11715.8 CAM36961.2 - 8.8e-06 24.6 11.3 0.014 14.0 0.1 5.5 1 1 5 6 6 6 3 Nucleoporin Nup120/160 RhlB PF12300.8 CAM36961.2 - 0.0086 16.2 1.9 0.68 10.1 0.3 2.8 2 1 1 3 3 3 1 ATP-dependent RNA helicase RhlB MRP-L46 PF11788.8 CAM36962.1 - 2.7e-12 47.5 0.0 8.5e-12 45.9 0.0 1.8 1 1 0 1 1 1 1 39S mitochondrial ribosomal protein L46 PUF PF00806.19 CAM36963.1 - 3.3e-25 86.3 7.2 2.8e-06 26.7 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat Glycolytic PF00274.19 CAM36963.1 - 0.13 10.9 0.1 0.21 10.3 0.1 1.2 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I DNApol_Exo PF18136.1 CAM36964.2 - 0.031 13.4 1.7 0.047 12.8 1.7 1.3 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain bZIP_1 PF00170.21 CAM36964.2 - 0.07 13.2 0.2 0.07 13.2 0.2 3.5 3 0 0 3 3 3 0 bZIP transcription factor EF1G PF00647.19 CAM36964.2 - 0.1 12.7 0.3 0.35 10.9 0.1 2.1 2 1 0 2 2 2 0 Elongation factor 1 gamma, conserved domain TolA_bind_tri PF16331.5 CAM36964.2 - 0.19 11.8 9.1 8.9 6.5 0.1 3.4 2 1 1 3 3 3 0 TolA binding protein trimerisation Uso1_p115_C PF04871.13 CAM36964.2 - 1.7 9.0 15.0 1.2 9.5 6.4 2.3 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region CdvA PF18822.1 CAM36964.2 - 5.4 6.9 10.4 1.4 8.8 1.5 3.0 2 1 1 3 3 3 0 CdvA-like coiled-coil domain TPR_MLP1_2 PF07926.12 CAM36964.2 - 6.3 6.9 20.0 18 5.4 18.5 2.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein XhlA PF10779.9 CAM36964.2 - 8.8 6.6 9.9 12 6.2 0.6 3.6 3 1 1 4 4 4 0 Haemolysin XhlA Patched PF02460.18 CAM36965.1 - 0.18 9.8 0.0 0.25 9.4 0.0 1.1 1 0 0 1 1 1 0 Patched family ABC2_membrane PF01061.24 CAM36966.1 - 1.1e-37 129.6 15.7 1.1e-37 129.6 15.7 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 CAM36966.1 - 7.6e-22 78.3 0.0 1.1e-21 77.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CAM36966.1 - 0.00021 21.2 0.1 0.11 12.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 CAM36966.1 - 0.00082 18.6 11.3 0.0014 17.8 11.3 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein SMC_N PF02463.19 CAM36966.1 - 0.0011 18.5 0.1 0.026 13.9 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CAM36966.1 - 0.0055 17.1 0.1 0.011 16.1 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 CAM36966.1 - 0.0085 16.0 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase NACHT PF05729.12 CAM36966.1 - 0.012 15.5 0.1 0.024 14.6 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 CAM36966.1 - 0.027 15.0 0.0 0.044 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CAM36966.1 - 0.048 13.4 0.4 0.1 12.3 0.4 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 CAM36966.1 - 0.069 13.2 0.4 0.12 12.5 0.4 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_24 PF13479.6 CAM36966.1 - 0.082 12.6 0.2 0.85 9.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CAM36966.1 - 0.09 13.0 0.0 0.45 10.8 0.0 2.1 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 CAM36966.1 - 0.12 12.4 0.1 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase TsaE PF02367.17 CAM36966.1 - 0.2 11.7 0.5 2 8.5 0.2 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PRK PF00485.18 CAM36966.1 - 0.2 11.3 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family CytochromB561_N PF09786.9 CAM36967.1 - 3.6e-09 36.2 0.1 6e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 Cytochrome B561, N terminal Pro_isomerase PF00160.21 CAM36968.1 - 1.6e-51 174.7 0.5 1.9e-51 174.5 0.5 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TFIIA_gamma_C PF02751.14 CAM36968.1 - 0.1 12.7 0.1 0.29 11.3 0.1 1.7 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit DUF1768 PF08719.11 CAM36969.1 - 1.3e-25 90.6 0.0 1.5e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Proteasome PF00227.26 CAM36970.1 - 2.4e-27 95.7 0.0 3.8e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit HD PF01966.22 CAM36972.1 - 1e-13 51.6 2.7 1.5e-13 51.0 0.2 2.1 2 0 0 2 2 2 1 HD domain PDEase_I PF00233.19 CAM36972.1 - 0.0002 21.2 0.0 0.00034 20.4 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HDOD PF08668.12 CAM36972.1 - 0.0022 17.5 0.0 0.0039 16.7 0.0 1.3 1 0 0 1 1 1 1 HDOD domain Trm112p PF03966.16 CAM36973.1 - 7e-08 32.9 0.0 2.7e-07 31.0 0.0 1.8 1 1 0 1 1 1 1 Trm112p-like protein zinc_ribbon_5 PF13719.6 CAM36973.1 - 0.057 13.2 1.5 0.49 10.2 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.6 CAM36973.1 - 0.062 13.2 0.1 0.062 13.2 0.1 1.8 2 0 0 2 2 2 0 zinc-ribbon domain zf-UDP PF14569.6 CAM36973.1 - 0.12 12.5 0.0 0.72 10.0 0.0 2.1 2 0 0 2 2 2 0 Zinc-binding RING-finger Kinesin PF00225.23 CAM36974.2 - 1.9e-69 234.2 0.0 2.6e-69 233.7 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CAM36974.2 - 3.2e-10 40.1 0.0 1.7e-08 34.5 0.0 2.3 2 0 0 2 2 2 2 Microtubule binding DUF4490 PF14892.6 CAM36978.1 - 0.0023 18.0 0.4 0.0042 17.1 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) SpoIIIAH PF12685.7 CAM36980.2 - 0.19 11.6 0.6 0.4 10.5 0.6 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein Leu_zip PF15294.6 CAM36981.1 - 2.9e-13 50.0 10.4 1.2e-06 28.2 1.1 2.4 1 1 1 2 2 2 2 Leucine zipper AAA_10 PF12846.7 CAM36981.1 - 0.087 11.7 1.3 0.11 11.4 0.6 1.5 2 0 0 2 2 2 0 AAA-like domain FAM184 PF15665.5 CAM36981.1 - 0.12 12.2 10.6 0.21 11.3 10.6 1.3 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Cep57_MT_bd PF06657.13 CAM36981.1 - 0.4 11.2 9.5 1.7 9.1 2.6 3.0 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 V-ATPase_G_2 PF16999.5 CAM36981.1 - 0.43 11.0 17.8 0.075 13.5 1.5 2.4 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit FliJ PF02050.16 CAM36981.1 - 0.46 10.7 18.9 30 4.9 19.4 2.7 1 1 1 2 2 2 0 Flagellar FliJ protein Spc7 PF08317.11 CAM36981.1 - 1.2 8.0 9.6 1.7 7.4 6.9 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.8 CAM36981.1 - 1.3 9.3 14.3 1.4 9.1 1.6 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding GAS PF13851.6 CAM36981.1 - 1.8 7.9 12.7 1.4 8.3 7.4 2.2 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 CAM36981.1 - 2.2 8.3 7.4 0.63 10.1 1.2 2.6 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) ZapB PF06005.12 CAM36981.1 - 2.5 8.6 11.4 3.3 8.2 5.9 2.6 2 0 0 2 2 2 0 Cell division protein ZapB Exonuc_VII_L PF02601.15 CAM36981.1 - 3.2 7.2 14.1 2.8 7.4 13.1 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit Baculo_PEP_C PF04513.12 CAM36981.1 - 3.3 7.8 8.7 9.4 6.3 3.6 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus XRN_N PF03159.18 CAM36982.1 - 4.5e-90 301.3 0.0 7.2e-90 300.6 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 CAM36982.1 - 4.5e-85 286.2 3.5 3.3e-55 187.8 1.2 2.3 1 1 1 2 2 2 2 Xrn1 helical domain XRN1_D1 PF18332.1 CAM36982.1 - 1.9e-22 80.0 0.0 3.1e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain SH3_12 PF18129.1 CAM36982.1 - 1.9e-16 59.9 0.1 4.7e-16 58.6 0.1 1.7 1 0 0 1 1 1 1 Xrn1 SH3-like domain DUF4441 PF14536.6 CAM36982.1 - 0.19 11.9 0.5 0.5 10.6 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) FHA PF00498.26 CAM36984.1 - 0.0046 17.3 0.0 0.01 16.2 0.0 1.5 1 0 0 1 1 1 1 FHA domain NIBRIN_BRCT_II PF16508.5 CAM36984.1 - 0.042 14.2 0.0 0.086 13.2 0.0 1.5 1 0 0 1 1 1 0 Second BRCT domain on Nijmegen syndrome breakage protein Yop-YscD_cpl PF16697.5 CAM36984.1 - 0.06 13.7 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain RNase_H PF00075.24 CAM36985.1 - 3.7e-29 101.7 1.3 2.6e-20 73.1 0.0 3.0 1 1 1 2 2 2 2 RNase H zf-MYND PF01753.18 CAM36986.1 - 1.4e-11 44.3 11.9 1.4e-11 44.3 11.9 2.0 3 0 0 3 3 3 1 MYND finger zf-C6H2 PF15801.5 CAM36986.1 - 0.029 14.7 2.8 0.029 14.7 2.8 2.9 4 0 0 4 4 4 0 zf-MYND-like zinc finger, mRNA-binding TPR_2 PF07719.17 CAM36989.1 - 0.021 14.9 9.6 0.75 10.1 0.8 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 CAM36989.1 - 0.14 12.7 10.7 0.85 10.2 10.7 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 CAM36989.1 - 0.32 10.9 4.0 2.4 8.1 0.5 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Sel1 PF08238.12 CAM36989.1 - 0.77 10.5 4.8 1 10.1 0.2 2.5 2 0 0 2 2 2 0 Sel1 repeat Exonuc_VII_L PF02601.15 CAM36989.1 - 4.3 6.8 9.9 13 5.3 9.7 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit HIP1_clath_bdg PF16515.5 CAM36989.1 - 4.4 8.0 12.7 3.1 8.5 9.1 2.4 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 V_ATPase_I PF01496.19 CAM36989.1 - 5.6 4.7 4.7 8.3 4.2 4.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_S9 PF00326.21 CAM36990.1 - 7.9e-33 113.7 0.0 1.4e-32 112.9 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 CAM36990.1 - 3.9e-26 91.8 0.0 6.8e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain 3Beta_HSD PF01073.19 CAM36991.1 - 1.2e-28 99.9 0.0 1.5e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 CAM36991.1 - 2e-17 63.5 0.0 2.8e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CAM36991.1 - 2.8e-10 40.4 0.0 4.1e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 CAM36991.1 - 1.8e-08 33.9 0.0 2.5e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 CAM36991.1 - 2.6e-05 23.8 0.0 3.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 CAM36991.1 - 0.00034 19.8 0.0 0.00054 19.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 CAM36991.1 - 0.024 14.2 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Gln-synt_C PF00120.24 CAM36993.1 - 2.8e-19 69.3 0.0 7.2e-19 68.0 0.0 1.6 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 CAM36993.1 - 3.5e-13 49.1 0.0 6.2e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain SnoaL_3 PF13474.6 CAM36993.1 - 0.17 12.1 0.0 0.34 11.2 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like domain zf_CCCH_4 PF18345.1 CAM36994.1 - 2.6e-06 27.3 2.6 2.6e-06 27.3 2.6 1.8 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_4 PF18044.1 CAM36994.1 - 3.9e-06 26.5 0.7 9.6e-06 25.3 0.7 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 CAM36994.1 - 7.9e-06 25.6 1.7 7.9e-06 25.6 1.7 2.1 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CAM36994.1 - 0.00054 20.6 0.1 0.0013 19.4 0.1 1.6 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 CAM36994.1 - 0.022 15.2 1.4 0.061 13.8 1.4 1.8 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger LRR_6 PF13516.6 CAM36994.1 - 0.16 12.1 0.0 3.4 8.0 0.0 2.4 2 0 0 2 2 2 0 Leucine Rich repeat Ribosomal_L19e PF01280.20 CAM36997.1 - 3.3e-60 202.3 11.2 3.3e-60 202.3 11.2 2.1 2 0 0 2 2 2 1 Ribosomal protein L19e Macoilin PF09726.9 CAM36997.1 - 0.94 8.0 17.0 0.99 7.9 17.0 1.1 1 0 0 1 1 1 0 Macoilin family UPF0242 PF06785.11 CAM36997.1 - 1.2 9.2 8.9 1.6 8.8 8.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PepSY_TM_like_2 PF16357.5 CAM36997.1 - 4.4 7.2 6.8 6.6 6.7 6.8 1.2 1 0 0 1 1 1 0 Putative PepSY_TM-like BT1 PF03092.16 CAM36997.1 - 4.5 5.4 4.5 6 5.0 4.5 1.1 1 0 0 1 1 1 0 BT1 family Presenilin PF01080.17 CAM36997.1 - 8.1 5.1 9.2 10 4.7 9.2 1.1 1 0 0 1 1 1 0 Presenilin Ribosomal_L19e PF01280.20 CAM36999.1 - 4.1e-60 202.0 11.2 4.1e-60 202.0 11.2 2.2 2 0 0 2 2 2 1 Ribosomal protein L19e Macoilin PF09726.9 CAM36999.1 - 1.2 7.7 17.2 1.3 7.5 17.2 1.2 1 0 0 1 1 1 0 Macoilin family UPF0242 PF06785.11 CAM36999.1 - 1.4 9.0 8.9 1.9 8.5 8.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus BT1 PF03092.16 CAM36999.1 - 2.9 6.0 4.0 3.9 5.6 4.0 1.1 1 0 0 1 1 1 0 BT1 family PepSY_TM_like_2 PF16357.5 CAM36999.1 - 5.2 7.0 6.8 8.1 6.4 6.8 1.3 1 0 0 1 1 1 0 Putative PepSY_TM-like Hid1 PF12722.7 CAM36999.1 - 8.9 4.3 8.1 11 4.0 8.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ribosomal_L19e PF01280.20 CAM37000.1 - 1.2e-15 57.8 6.7 1.2e-15 57.8 6.7 2.2 2 0 0 2 2 2 1 Ribosomal protein L19e RIFIN PF02009.16 CAM37000.1 - 0.016 15.1 6.6 0.021 14.7 6.6 1.2 1 0 0 1 1 1 0 Rifin Macoilin PF09726.9 CAM37000.1 - 0.54 8.8 16.7 0.63 8.5 16.7 1.2 1 0 0 1 1 1 0 Macoilin family UPF0242 PF06785.11 CAM37000.1 - 0.63 10.1 9.0 0.75 9.9 9.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Virul_Fac PF10139.9 CAM37000.1 - 0.81 7.8 12.8 0.94 7.6 12.8 1.0 1 0 0 1 1 1 0 Putative bacterial virulence factor BT1 PF03092.16 CAM37000.1 - 0.97 7.6 3.9 1.2 7.3 3.9 1.1 1 0 0 1 1 1 0 BT1 family Rrn6 PF10214.9 CAM37000.1 - 1.6 7.2 8.0 1.7 7.0 8.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor PepSY_TM_like_2 PF16357.5 CAM37000.1 - 2.2 8.2 6.9 2.9 7.8 6.9 1.2 1 0 0 1 1 1 0 Putative PepSY_TM-like DDHD PF02862.17 CAM37000.1 - 2.6 8.1 6.1 3 8.0 6.1 1.2 1 0 0 1 1 1 0 DDHD domain ALMT PF11744.8 CAM37000.1 - 3 6.6 7.6 3.3 6.4 7.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Hid1 PF12722.7 CAM37000.1 - 3.9 5.5 8.5 4.3 5.3 8.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PIEZO PF15917.5 CAM37000.1 - 4 6.9 11.6 5.1 6.5 11.6 1.2 1 0 0 1 1 1 0 Piezo XRN_M PF17846.1 CAM37000.1 - 4.1 6.2 9.8 5.2 5.9 9.8 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Neur_chan_memb PF02932.16 CAM37000.1 - 5.1 7.1 7.6 6 6.9 7.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GREB1 PF15782.5 CAM37000.1 - 5.3 4.0 7.9 5.7 3.9 7.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Presenilin PF01080.17 CAM37000.1 - 5.4 5.7 10.0 6 5.5 10.0 1.1 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 CAM37000.1 - 6.6 4.5 6.4 6.2 4.6 6.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4813 PF16072.5 CAM37000.1 - 9.9 5.7 29.9 12 5.4 29.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Kinesin PF00225.23 CAM37002.1 - 4.9e-10 38.8 4.7 0.00011 21.2 0.0 2.9 3 0 0 3 3 3 2 Kinesin motor domain DUF3074 PF11274.8 CAM37002.1 - 0.081 12.9 0.0 0.081 12.9 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3074) TMF_DNA_bd PF12329.8 CAM37002.1 - 0.41 10.7 10.1 0.099 12.7 4.9 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding UPF0231 PF06062.11 CAM37002.1 - 0.56 10.5 6.5 0.38 11.0 0.3 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0231) DUF2730 PF10805.8 CAM37002.1 - 1.6 8.9 6.3 0.44 10.7 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) TMPIT PF07851.13 CAM37002.1 - 4.9 6.3 10.6 2.5 7.2 8.0 1.8 1 1 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.6 CAM37002.1 - 5.1 6.4 17.7 0.32 10.3 11.2 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) TPR_12 PF13424.6 CAM37003.2 - 7.6e-07 29.3 1.2 0.00051 20.3 0.4 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 CAM37003.2 - 5.1e-05 23.0 3.8 0.04 13.8 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CAM37003.2 - 0.00024 20.8 3.0 0.032 14.0 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 CAM37003.2 - 0.0054 16.8 1.1 0.05 13.7 0.0 3.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 CAM37003.2 - 0.031 14.3 0.0 6.9 7.0 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 CAM37003.2 - 0.1 13.1 4.0 0.22 12.0 1.7 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat ABA_WDS PF02496.16 CAM37004.2 - 0.12 12.9 0.2 0.12 12.9 0.2 2.0 2 0 0 2 2 2 0 ABA/WDS induced protein NAD_kinase PF01513.21 CAM37005.2 - 1.9e-10 40.4 0.0 7.6e-10 38.5 0.0 2.0 2 0 0 2 2 2 1 ATP-NAD kinase Cnd2 PF05786.14 CAM37006.2 - 3.5e-27 95.5 2.1 2.7e-17 62.8 0.0 3.2 3 0 0 3 3 3 3 Condensin complex subunit 2 CNDH2_N PF06278.11 CAM37006.2 - 0.021 15.0 0.0 0.048 13.9 0.0 1.5 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal SpoU_methylase PF00588.19 CAM37009.1 - 1.6e-14 54.3 0.0 1.1e-11 45.1 0.0 3.0 2 1 0 2 2 2 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 CAM37009.1 - 1.4e-05 25.2 0.0 0.00024 21.3 0.0 2.3 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding DUF4691 PF15762.5 CAM37009.1 - 0.075 13.2 0.3 0.19 11.8 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4691) HHH_3 PF12836.7 CAM37009.1 - 0.14 12.4 0.1 0.26 11.6 0.1 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif U-box PF04564.15 CAM37010.2 - 1.9e-11 44.0 0.0 3.6e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 U-box domain LRR_4 PF12799.7 CAM37011.2 - 1.7e-13 50.5 1.4 0.67 10.5 0.0 8.6 9 2 1 10 10 10 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM37011.2 - 8.2e-06 25.5 9.1 5.3 6.9 0.1 8.5 8 2 2 10 10 10 3 Leucine rich repeat LRR_6 PF13516.6 CAM37011.2 - 0.00011 22.0 7.6 0.45 10.7 0.1 8.0 8 0 0 8 8 8 1 Leucine Rich repeat Maf_N PF08383.11 CAM37012.1 - 0.11 12.3 0.1 0.11 12.3 0.1 2.0 2 0 0 2 2 2 0 Maf N-terminal region DUF2057 PF09829.9 CAM37012.1 - 1.1 9.3 4.3 4.3 7.5 1.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) STAT1_TAZ2bind PF12162.8 CAM37012.1 - 1.4 8.6 2.6 2.6 7.7 0.3 2.5 3 0 0 3 3 3 0 STAT1 TAZ2 binding domain SUIM_assoc PF16619.5 CAM37013.2 - 0.78 9.9 4.9 7.6 6.7 1.0 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CAM37014.2 - 2.3 8.1 5.3 0.48 10.4 1.2 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit dUTPase_2 PF08761.11 CAM37015.1 - 7e-46 156.4 0.0 9.2e-46 156.0 0.0 1.2 1 0 0 1 1 1 1 dUTPase Ribosomal_L23 PF00276.20 CAM37016.1 - 3e-15 56.3 2.9 3e-15 56.3 2.9 2.6 2 1 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.13 CAM37016.1 - 0.00018 21.6 7.0 0.00055 20.1 7.0 1.8 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 CAM37017.1 - 3e-15 56.3 2.9 3e-15 56.3 2.9 2.6 2 1 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.13 CAM37017.1 - 0.00018 21.6 7.0 0.00055 20.1 7.0 1.8 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain PHD PF00628.29 CAM37019.2 - 0.00041 20.2 0.7 0.00041 20.2 0.7 1.8 2 0 0 2 2 2 1 PHD-finger Pro_CA PF00484.19 CAM37020.1 - 2.9e-41 141.4 3.5 7e-40 136.9 3.5 2.3 1 1 0 1 1 1 1 Carbonic anhydrase DUF89 PF01937.19 CAM37021.2 - 4e-42 144.4 0.0 3.6e-22 78.8 0.0 4.4 4 0 0 4 4 4 4 Protein of unknown function DUF89 Put_Phosphatase PF06888.12 CAM37021.2 - 2.2e-30 105.8 1.6 2.1e-13 50.2 0.0 3.3 2 1 1 3 3 3 3 Putative Phosphatase HAD PF12710.7 CAM37021.2 - 0.0052 17.2 0.1 0.14 12.5 0.1 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 CAM37022.2 - 8.4e-47 159.7 0.0 4.8e-36 124.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM37022.2 - 1.5e-30 106.3 0.0 1.7e-22 80.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase FHA PF00498.26 CAM37022.2 - 2.2e-09 37.5 0.0 7.8e-09 35.8 0.0 2.0 2 0 0 2 2 2 1 FHA domain PAS PF00989.25 CAM37022.2 - 0.0017 18.3 0.0 0.28 11.2 0.0 2.8 2 0 0 2 2 2 1 PAS fold Kinase-like PF14531.6 CAM37022.2 - 0.0033 16.8 0.0 0.0065 15.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CAM37022.2 - 0.038 12.8 0.0 0.073 11.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase SQHop_cyclase_N PF13249.6 CAM37023.2 - 2.4e-45 154.9 1.0 1.5e-40 139.1 0.1 3.9 3 1 1 4 4 4 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 CAM37023.2 - 3.9e-37 128.1 1.2 2.2e-33 115.7 0.4 2.7 3 0 0 3 3 3 2 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 CAM37023.2 - 2.8e-24 84.6 14.6 1.2e-09 37.8 0.0 5.5 5 1 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 CAM37023.2 - 0.0042 16.2 0.0 0.011 14.7 0.0 1.7 2 0 0 2 2 2 1 A-macroglobulin TED domain Pec_lyase PF09492.10 CAM37023.2 - 0.038 13.3 0.0 2.6 7.3 0.0 3.1 2 1 1 3 3 3 0 Pectic acid lyase NDUF_B7 PF05676.13 CAM37026.1 - 0.0001 21.9 3.7 0.00018 21.2 3.7 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 CAM37026.1 - 0.0004 20.3 3.7 0.00072 19.5 3.7 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 CAM37026.1 - 0.34 11.0 2.4 1.8 8.7 0.2 2.2 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 CAM37026.1 - 1.8 8.8 5.0 3 8.1 5.0 1.4 1 0 0 1 1 1 0 CHCH domain Ctf8 PF09696.10 CAM37027.1 - 1.2e-10 41.9 0.0 0.0026 18.1 0.0 3.2 3 0 0 3 3 3 3 Ctf8 DUF3275 PF11679.8 CAM37027.1 - 0.21 11.6 0.2 0.45 10.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) AAA_lid_7 PF17867.1 CAM37028.2 - 0.073 13.3 0.2 0.4 10.9 0.2 2.4 1 0 0 1 1 1 0 Midasin AAA lid domain DZR PF12773.7 CAM37028.2 - 3 7.9 9.4 1.6 8.8 0.2 3.4 3 0 0 3 3 3 0 Double zinc ribbon YEATS PF03366.16 CAM37029.1 - 2e-15 56.5 0.0 3.7e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 YEATS family SDA1 PF05285.12 CAM37029.1 - 0.0076 15.7 11.0 0.014 14.8 11.0 1.3 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 CAM37029.1 - 0.54 8.4 15.8 0.82 7.8 15.8 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 CAM37029.1 - 4.6 5.4 12.8 8.5 4.5 12.8 1.3 1 0 0 1 1 1 0 CDC45-like protein PALP PF00291.25 CAM37030.1 - 7.2e-57 193.0 0.2 8.2e-57 192.9 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FAA_hydrolase_N PF09298.11 CAM37031.2 - 3.7 7.8 6.3 1.1 9.5 2.0 2.3 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal HlyIII PF03006.20 CAM37032.1 - 1.2e-14 54.6 10.1 6.7e-08 32.5 2.3 2.8 2 1 0 2 2 2 2 Haemolysin-III related RRM_1 PF00076.22 CAM37034.2 - 4.5e-25 87.3 0.0 1.2e-13 50.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 CAM37034.2 - 0.012 15.9 0.0 3.4 7.9 0.0 2.7 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Phage_tail_T PF06223.12 CAM37037.1 - 0.0053 17.3 0.1 0.011 16.3 0.1 1.5 1 0 0 1 1 1 1 Minor tail protein T ADIP PF11559.8 CAM37037.1 - 0.0095 16.0 6.3 0.68 10.0 0.0 2.4 2 0 0 2 2 2 2 Afadin- and alpha -actinin-Binding DUF4618 PF15397.6 CAM37037.1 - 0.57 9.6 5.8 2.6 7.4 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4618) Pil1 PF13805.6 CAM37037.1 - 0.65 9.4 8.1 1.4 8.3 2.6 2.2 2 0 0 2 2 2 0 Eisosome component PIL1 DUF3377 PF11857.8 CAM37037.1 - 3.1 7.8 4.7 0.39 10.7 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) LNS2 PF08235.13 CAM37038.1 - 2.5e-81 272.5 0.0 3.6e-81 271.9 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 CAM37038.1 - 9.1e-19 67.3 0.0 2.4e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 CAM37038.1 - 0.099 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Use1 PF09753.9 CAM37039.1 - 0.047 13.4 0.2 0.064 13.0 0.2 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 EF-hand_1 PF00036.32 CAM37040.1 - 0.069 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 CAM37040.1 - 0.16 12.5 0.0 0.36 11.3 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair Thymidylat_synt PF00303.19 CAM37041.1 - 1.1e-108 362.4 0.0 1.6e-108 361.9 0.0 1.3 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.19 CAM37041.1 - 8.2e-23 80.9 0.0 9.2e-22 77.5 0.0 2.5 1 1 0 1 1 1 1 Dihydrofolate reductase PrmA PF06325.13 CAM37042.1 - 2.7e-08 33.5 0.0 4.1e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 CAM37042.1 - 3.7e-06 27.5 0.0 9.6e-06 26.2 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 CAM37042.1 - 3.1e-05 23.6 0.0 5.2e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 CAM37042.1 - 3.1e-05 23.8 0.0 4.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PCMT PF01135.19 CAM37042.1 - 0.001 18.9 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.15 CAM37042.1 - 0.0014 18.3 0.0 0.0027 17.4 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 RrnaAD PF00398.20 CAM37042.1 - 0.0018 17.4 0.0 0.0028 16.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Met_10 PF02475.16 CAM37042.1 - 0.0066 16.2 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_11 PF08241.12 CAM37042.1 - 0.014 16.0 0.0 0.034 14.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 CAM37042.1 - 0.016 16.0 0.0 0.043 14.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain CMAS PF02353.20 CAM37042.1 - 0.021 14.1 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 CAM37042.1 - 0.077 12.8 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 CAM37042.1 - 0.083 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Acyl-CoA_dh_1 PF00441.24 CAM37043.1 - 7e-47 159.4 3.4 7e-47 159.4 3.4 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CAM37043.1 - 2.3e-28 99.1 0.2 6e-28 97.8 0.2 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CAM37043.1 - 1.3e-25 89.4 0.2 3.6e-25 88.0 0.2 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CAM37043.1 - 1.4e-20 73.9 2.2 1.4e-20 73.9 2.2 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 CAM37043.1 - 0.087 12.5 0.3 0.51 9.9 0.3 2.3 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Acyl-CoA_dh_1 PF00441.24 CAM37045.1 - 1.1e-46 158.8 3.5 1.7e-46 158.2 3.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CAM37045.1 - 1.6e-28 99.6 0.2 4.2e-28 98.3 0.2 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CAM37045.1 - 8.3e-26 90.0 0.2 2.6e-25 88.5 0.2 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CAM37045.1 - 9.2e-21 74.5 2.1 1.6e-20 73.7 2.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 CAM37045.1 - 0.054 13.2 0.4 0.37 10.4 0.4 2.4 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal PP2C PF00481.21 CAM37046.2 - 1.5e-24 87.1 0.2 2.1e-15 57.1 0.0 3.5 3 0 0 3 3 3 3 Protein phosphatase 2C SpoIIE PF07228.12 CAM37046.2 - 0.11 12.4 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) PTH2 PF01981.16 CAM37047.1 - 2e-44 150.6 0.8 2.8e-44 150.2 0.8 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Oxidored_FMN PF00724.20 CAM37049.1 - 1.6e-40 139.4 0.0 2.1e-40 139.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 CAM37049.1 - 2.1e-15 56.8 0.0 6.1e-15 55.2 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CAM37049.1 - 3e-10 40.2 0.0 9.5e-10 38.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CAM37049.1 - 2.1e-07 31.4 0.7 0.00057 20.4 0.5 3.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CAM37049.1 - 2.9e-07 29.9 0.4 4.7e-07 29.2 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 CAM37049.1 - 6.2e-07 29.1 0.0 1.1e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CAM37049.1 - 1.7e-06 27.0 1.8 5.7e-06 25.3 0.1 2.4 2 1 1 3 3 3 1 HI0933-like protein DAO PF01266.24 CAM37049.1 - 2.4e-06 27.4 0.5 5.2e-06 26.3 0.5 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CAM37049.1 - 0.00069 19.0 0.2 0.0053 16.1 0.1 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CAM37049.1 - 0.0011 18.1 0.2 0.0017 17.5 0.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 CAM37049.1 - 0.003 16.9 0.1 0.0051 16.2 0.1 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 CAM37049.1 - 0.0036 16.6 0.0 0.0074 15.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 CAM37049.1 - 0.0089 15.3 0.1 0.015 14.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 CAM37049.1 - 0.023 14.3 0.5 0.074 12.7 0.3 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 CAM37049.1 - 0.037 13.9 0.0 0.099 12.5 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 CAM37049.1 - 0.042 14.3 0.2 1.1 9.7 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.23 CAM37049.1 - 0.051 13.6 0.1 0.13 12.2 0.1 1.7 2 0 0 2 2 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FMO-like PF00743.19 CAM37049.1 - 0.06 11.8 0.1 2.1 6.7 0.0 2.1 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 CAM37049.1 - 0.073 13.1 0.1 0.2 11.7 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding TLD PF07534.16 CAM37050.1 - 1.3e-08 35.1 0.0 3.5e-05 24.0 0.0 3.2 3 0 0 3 3 3 3 TLD SIS PF01380.22 CAM37051.1 - 4.5e-50 168.9 0.8 5.6e-28 97.4 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 CAM37051.1 - 5.6e-16 59.0 0.0 1.1e-15 58.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CAM37051.1 - 3.7e-09 36.5 0.0 7.9e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 CAM37051.1 - 0.00029 19.9 0.0 0.00051 19.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Mob1_phocein PF03637.17 CAM37052.1 - 3e-68 229.1 0.2 3.8e-68 228.8 0.2 1.0 1 0 0 1 1 1 1 Mob1/phocein family Ntox8 PF15545.6 CAM37052.1 - 0.1 12.7 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial toxin 8 DUF3883 PF13020.6 CAM37053.2 - 2.1e-16 59.7 0.0 3.9e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) LRR_8 PF13855.6 CAM37054.2 - 3.8e-20 71.4 16.8 7.2e-08 32.1 0.7 5.5 5 1 0 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 CAM37054.2 - 1.2e-10 41.5 12.6 0.39 11.2 0.0 6.8 4 3 4 8 8 8 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CAM37054.2 - 0.0024 17.4 0.4 0.47 9.9 0.2 2.8 3 0 0 3 3 3 2 Leucine-rich repeat GRDP-like PF07173.12 CAM37054.2 - 0.004 17.8 0.8 17 6.0 0.0 3.9 4 0 0 4 4 4 1 Glycine-rich domain-containing protein-like LRR_1 PF00560.33 CAM37054.2 - 0.014 15.9 17.2 57 4.8 0.1 9.9 11 1 0 11 11 11 0 Leucine Rich Repeat LRR_6 PF13516.6 CAM37054.2 - 3.4 8.0 24.8 51 4.3 0.0 8.9 10 0 0 10 10 10 0 Leucine Rich repeat WD40 PF00400.32 CAM37055.2 - 0.019 15.8 0.4 0.24 12.3 0.0 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat DUF5009 PF16401.5 CAM37055.2 - 0.2 11.1 0.6 0.35 10.3 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5009) SET PF00856.28 CAM37056.2 - 3.8e-14 53.4 0.0 1.1e-13 52.0 0.0 1.8 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 CAM37056.2 - 5.4e-05 23.2 10.1 5.4e-05 23.2 10.1 3.2 3 1 0 3 3 3 1 MYND finger G-patch PF01585.23 CAM37058.1 - 1.2e-11 44.3 0.8 1.8e-11 43.7 0.8 1.3 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CAM37058.1 - 9.4e-07 28.8 0.6 2e-06 27.8 0.6 1.5 1 0 0 1 1 1 1 G-patch domain Kinesin PF00225.23 CAM37059.1 - 6.3e-61 206.1 0.0 1.8e-60 204.6 0.0 1.7 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CAM37059.1 - 2.1e-11 44.0 0.0 6.9e-11 42.3 0.0 1.8 1 1 0 1 1 1 1 Microtubule binding AAA_22 PF13401.6 CAM37059.1 - 0.019 15.3 0.2 0.27 11.5 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CAM37059.1 - 0.04 14.3 0.0 0.14 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 CAM37059.1 - 0.041 13.0 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 CAM37059.1 - 0.054 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF87 PF01935.17 CAM37059.1 - 0.15 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain Aminotran_3 PF00202.21 CAM37059.1 - 0.15 10.6 0.1 0.24 10.0 0.1 1.2 1 0 0 1 1 1 0 Aminotransferase class-III OmpH PF03938.14 CAM37059.1 - 0.54 10.6 3.7 4.8 7.5 0.2 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) BRE1 PF08647.11 CAM37059.1 - 1.3 9.1 4.4 0.22 11.6 0.7 1.6 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase ATG16 PF08614.11 CAM37059.1 - 1.7 8.9 9.1 1.9 8.7 2.9 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 CAM37060.2 - 2.2 7.1 36.8 0.055 12.3 9.9 3.5 2 1 2 4 4 4 0 Spc7 kinetochore protein Thioredoxin PF00085.20 CAM37061.1 - 1.2e-26 92.7 0.0 1.4e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CAM37061.1 - 9.2e-07 29.3 0.0 1.6e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CAM37061.1 - 9.8e-05 22.5 0.0 0.00016 21.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 CAM37061.1 - 0.00011 21.7 0.0 0.00015 21.2 0.0 1.3 1 1 0 1 1 1 1 OST3 / OST6 family, transporter family TraF PF13728.6 CAM37061.1 - 0.00039 20.3 0.0 0.00055 19.8 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_5 PF13743.6 CAM37061.1 - 0.022 14.5 0.0 2.8 7.6 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_8 PF13905.6 CAM37061.1 - 0.08 13.3 0.0 0.58 10.5 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin-like 2OG-FeII_Oxy_2 PF13532.6 CAM37062.1 - 5.1e-08 33.3 0.0 1.1e-06 28.9 0.1 2.1 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily TEX12 PF15219.6 CAM37062.1 - 0.13 12.6 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 Testis-expressed 12 DeoC PF01791.9 CAM37063.2 - 3.1e-13 49.9 8.5 4.1e-13 49.5 8.5 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase Profilin PF00235.19 CAM37063.2 - 0.18 12.1 1.2 0.76 10.0 0.1 2.3 2 1 0 2 2 2 0 Profilin Sporozoite_P67 PF05642.11 CAM37065.1 - 0.028 12.5 0.4 0.057 11.5 0.4 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RNA_polI_A34 PF08208.11 CAM37065.1 - 0.29 11.2 4.2 6.1 6.9 0.1 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 SPOR PF05036.13 CAM37065.1 - 0.46 10.9 3.5 1.7 9.1 3.5 2.1 1 0 0 1 1 1 0 Sporulation related domain Shugoshin_N PF07558.11 CAM37065.1 - 0.98 9.3 13.6 3.4 7.6 0.3 4.3 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region MAD PF05557.13 CAM37065.1 - 1.2 7.5 49.4 0.38 9.1 3.5 3.1 2 1 1 3 3 3 0 Mitotic checkpoint protein CALCOCO1 PF07888.11 CAM37065.1 - 5.1 5.9 49.1 0.11 11.3 23.9 3.2 2 1 1 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like Troponin PF00992.20 CAM37065.1 - 8.9 6.6 35.6 0.037 14.3 7.7 5.5 4 2 2 6 6 6 0 Troponin PIG-X PF08320.12 CAM37068.1 - 3.4e-06 27.1 0.2 2.5e-05 24.3 0.2 2.0 1 1 0 1 1 1 1 PIG-X / PBN1 WD40 PF00400.32 CAM37069.1 - 3.4e-06 27.7 2.9 0.0014 19.4 0.4 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM37069.1 - 1.6e-05 25.1 0.5 0.0077 16.5 0.0 3.3 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain RTT107_BRCT_5 PF16770.5 CAM37070.1 - 1.7e-05 24.6 0.0 3.5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 CAM37070.1 - 0.0075 16.6 0.0 0.024 15.0 0.0 1.8 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain DUF4379 PF14311.6 CAM37071.2 - 8.3e-26 90.1 21.7 8.8e-09 35.6 0.2 4.7 4 0 0 4 4 4 4 Probable Zinc-ribbon domain HypA PF01155.19 CAM37071.2 - 3.1e-05 24.0 14.2 0.088 12.8 0.1 4.5 5 0 0 5 5 5 3 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_ribbon_SprT PF17283.2 CAM37071.2 - 0.02 14.8 3.4 0.02 14.8 3.4 5.5 6 1 0 6 6 6 0 SprT-like zinc ribbon domain RNHCP PF12647.7 CAM37071.2 - 1.5 8.9 0.0 1.5 8.9 0.0 4.9 4 2 1 5 5 5 0 RNHCP domain NTF2 PF02136.20 CAM37073.1 - 3.4e-16 59.9 0.0 3.9e-16 59.7 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Pkinase PF00069.25 CAM37074.1 - 3.8e-60 203.5 0.0 1.6e-58 198.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM37074.1 - 3.7e-32 111.6 0.0 1.2e-22 80.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CAM37074.1 - 6e-05 23.1 0.1 0.11 12.4 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CAM37074.1 - 0.00035 20.0 0.0 0.0018 17.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CAM37074.1 - 0.017 14.5 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CAM37074.1 - 0.07 12.1 0.0 0.096 11.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 CAM37074.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Thioredoxin PF00085.20 CAM37075.1 - 8.3e-12 45.0 0.0 1e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 CAM37075.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.5 1 1 0 1 1 1 0 OST3 / OST6 family, transporter family PCO_ADO PF07847.12 CAM37080.1 - 3.5e-49 167.0 0.0 4.3e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 PCO_ADO CDO_I PF05995.12 CAM37080.1 - 0.0054 16.1 0.2 2 7.7 0.0 2.2 2 0 0 2 2 2 2 Cysteine dioxygenase type I Cupin_2 PF07883.11 CAM37080.1 - 0.069 12.9 0.0 4.3 7.1 0.0 2.9 3 0 0 3 3 3 0 Cupin domain FAD_binding_3 PF01494.19 CAM37081.2 - 7.9e-11 41.8 0.0 8.5e-10 38.4 0.0 2.3 2 1 0 2 2 2 1 FAD binding domain SE PF08491.10 CAM37081.2 - 0.023 13.8 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase DUF2956 PF11169.8 CAM37082.1 - 0.027 14.7 0.1 0.94 9.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) DFF-C PF09033.10 CAM37082.1 - 0.25 11.2 3.5 0.45 10.4 3.0 1.6 2 0 0 2 2 2 0 DNA Fragmentation factor 45kDa, C terminal domain BT1 PF03092.16 CAM37083.1 - 1.9e-191 636.9 14.5 2.2e-191 636.7 14.5 1.0 1 0 0 1 1 1 1 BT1 family MFS_1 PF07690.16 CAM37083.1 - 0.28 10.1 47.5 0.24 10.3 9.9 3.5 1 1 1 2 2 2 0 Major Facilitator Superfamily NiFe_hyd_3_EhaA PF17367.2 CAM37083.1 - 1.6 8.9 14.3 21 5.4 6.9 3.7 2 1 0 2 2 2 0 NiFe-hydrogenase-type-3 Eha complex subunit A DUF4131 PF13567.6 CAM37083.1 - 9.6 5.8 13.6 31 4.2 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Coprogen_oxidas PF01218.18 CAM37084.1 - 4.5e-131 435.9 0.1 5.1e-131 435.8 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Flavodoxin_5 PF12724.7 CAM37085.1 - 6.8e-48 162.6 0.0 9.9e-48 162.0 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_3 PF12641.7 CAM37085.1 - 0.00056 19.6 0.0 0.00083 19.1 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_1 PF00258.25 CAM37085.1 - 0.03 14.5 0.1 0.043 14.0 0.1 1.3 1 0 0 1 1 1 0 Flavodoxin DUF2194 PF09960.9 CAM37085.1 - 0.13 10.6 0.0 0.15 10.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) Cyt-b5 PF00173.28 CAM37086.1 - 2.5e-06 27.5 0.0 2.9e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CD225 PF04505.12 CAM37086.1 - 0.1 12.7 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Interferon-induced transmembrane protein C2 PF00168.30 CAM37088.2 - 9.8e-10 38.7 0.0 1.9e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain SMC_N PF02463.19 CAM37089.1 - 3.1e-60 203.3 1.7 4.1e-60 203.0 1.7 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CAM37089.1 - 1.1e-22 80.6 0.0 3.6e-22 78.9 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 CAM37089.1 - 1.3e-15 58.5 2.2 1.3e-15 58.5 2.2 5.0 2 2 1 3 3 1 1 AAA domain AAA_21 PF13304.6 CAM37089.1 - 3.8e-14 53.2 1.7 4.3e-06 26.8 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CAM37089.1 - 4.7e-14 52.9 17.8 1.6e-11 44.6 9.6 3.1 2 1 1 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 CAM37089.1 - 0.0053 16.5 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Myb_DNA-binding PF00249.31 CAM37089.1 - 0.078 13.2 1.1 0.4 10.9 1.1 2.3 1 0 0 1 1 1 0 Myb-like DNA-binding domain RsgA_GTPase PF03193.16 CAM37089.1 - 0.12 12.3 1.5 11 5.8 0.0 3.3 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 CAM37089.1 - 0.37 11.3 19.5 0.17 12.4 0.2 5.2 3 2 0 3 3 2 0 ABC transporter IL5 PF02025.15 CAM37089.1 - 0.37 11.1 3.0 12 6.3 0.4 3.4 3 0 0 3 3 3 0 Interleukin 5 DASH_Dam1 PF08653.10 CAM37089.1 - 9 6.2 8.3 3.9 7.3 0.1 3.9 4 0 0 4 4 4 0 DASH complex subunit Dam1 ChuX_HutX PF06228.13 CAM37090.1 - 0.17 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Haem utilisation ChuX/HutX Synaptobrevin PF00957.21 CAM37091.1 - 8.2e-31 105.6 4.5 1.5e-30 104.8 4.5 1.5 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CAM37091.1 - 0.02 14.9 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 Regulated-SNARE-like domain FtsK_SpoIIIE PF01580.18 CAM37091.1 - 0.039 13.3 0.2 0.059 12.7 0.2 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF4844 PF16133.5 CAM37091.1 - 0.044 14.3 1.0 0.09 13.3 0.6 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4844) His_Phos_1 PF00300.22 CAM37094.1 - 4.4e-36 124.4 0.0 4.9e-36 124.3 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ASCH PF04266.14 CAM37095.1 - 1.7e-16 60.7 0.0 5.4e-16 59.1 0.0 1.9 1 0 0 1 1 1 1 ASCH domain zf-C2HC5 PF06221.13 CAM37095.1 - 8.6e-05 22.5 9.9 0.00019 21.3 9.9 1.6 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type DEAD PF00270.29 CAM37096.1 - 2.1e-37 128.6 0.0 3.7e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAM37096.1 - 3.7e-23 82.0 0.0 1.1e-22 80.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAM37096.1 - 2.9e-05 24.2 0.0 5.4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CAM37096.1 - 5.2e-05 23.5 0.0 0.00019 21.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain SecA_DEAD PF07517.14 CAM37096.1 - 0.017 14.4 0.0 0.11 11.7 0.0 2.1 1 1 0 1 1 1 0 SecA DEAD-like domain GFRP PF06399.13 CAM37096.1 - 0.089 12.7 0.0 0.96 9.4 0.0 2.7 3 0 0 3 3 3 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) Adaptin_N PF01602.20 CAM37097.2 - 6.1e-81 272.5 1.2 6.4e-81 272.5 0.2 1.5 2 0 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.7 CAM37097.2 - 1.2e-10 41.7 0.2 9.2e-07 29.0 0.0 2.4 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CAM37097.2 - 0.00038 20.8 1.2 1.6 9.2 0.3 3.8 2 1 1 3 3 3 2 HEAT repeats Vac14_Fab1_bd PF12755.7 CAM37097.2 - 0.005 17.4 0.1 0.16 12.6 0.0 2.6 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 CAM37097.2 - 0.0054 16.9 0.1 0.037 14.2 0.1 2.3 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm_2 PF04826.13 CAM37097.2 - 0.021 14.3 0.3 0.047 13.2 0.1 1.6 2 0 0 2 2 2 0 Armadillo-like HEAT PF02985.22 CAM37097.2 - 0.023 15.0 9.6 0.54 10.7 0.1 5.0 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.6 CAM37097.2 - 0.033 14.7 1.6 5.7 7.5 0.0 3.7 3 0 0 3 3 3 0 HEAT-like repeat Cnd3 PF12719.7 CAM37097.2 - 0.048 12.8 0.3 0.11 11.7 0.3 1.5 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain DSPc PF00782.20 CAM37098.1 - 1.2e-27 96.3 0.1 2.4e-27 95.3 0.1 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.13 CAM37098.1 - 0.014 15.0 0.0 1.9 8.0 0.0 2.8 3 0 0 3 3 3 0 Tyrosine phosphatase family Init_tRNA_PT PF04179.12 CAM37098.1 - 0.038 14.3 0.0 0.088 13.1 0.0 1.6 1 0 0 1 1 1 0 Rit1 DUSP-like domain Y_phosphatase PF00102.27 CAM37098.1 - 0.086 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase RRM_1 PF00076.22 CAM37098.1 - 0.14 12.0 0.0 0.38 10.6 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PTPlike_phytase PF14566.6 CAM37098.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate BLOC1_2 PF10046.9 CAM37099.1 - 0.012 15.8 11.0 0.017 15.4 4.2 2.8 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SCP-1 PF05483.12 CAM37099.1 - 0.018 13.1 10.1 0.029 12.4 10.1 1.2 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) Macoilin PF09726.9 CAM37099.1 - 0.16 10.5 8.7 0.26 9.8 8.7 1.3 1 0 0 1 1 1 0 Macoilin family NPV_P10 PF05531.12 CAM37099.1 - 0.22 12.0 4.8 7.7 7.1 0.2 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein CENP-Q PF13094.6 CAM37099.1 - 0.23 11.7 14.8 0.46 10.7 13.3 2.1 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4407 PF14362.6 CAM37099.1 - 0.32 10.3 12.8 0.57 9.5 12.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMPIT PF07851.13 CAM37099.1 - 0.34 10.1 4.7 0.53 9.5 4.7 1.4 1 0 0 1 1 1 0 TMPIT-like protein CENP-K PF11802.8 CAM37099.1 - 0.39 10.3 9.0 0.8 9.2 9.0 1.5 1 0 0 1 1 1 0 Centromere-associated protein K CorA PF01544.18 CAM37099.1 - 0.57 9.4 8.5 1 8.6 8.5 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein GAS PF13851.6 CAM37099.1 - 0.69 9.2 16.5 0.13 11.6 10.6 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Cnn_1N PF07989.11 CAM37099.1 - 0.72 10.0 11.3 0.5 10.6 7.5 2.4 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 HALZ PF02183.18 CAM37099.1 - 1.7 9.0 10.3 0.12 12.6 0.5 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper Seryl_tRNA_N PF02403.22 CAM37099.1 - 4.6 7.5 11.3 6.7 7.0 9.3 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain AATF-Che1 PF13339.6 CAM37099.1 - 5 7.8 11.1 4.1 8.1 0.6 2.6 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor RasGAP_C PF03836.15 CAM37099.1 - 6 7.0 8.5 4.8 7.3 3.1 2.3 1 1 1 2 2 2 0 RasGAP C-terminus Rootletin PF15035.6 CAM37099.1 - 6.4 6.8 18.5 10 6.1 16.5 2.0 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion PRKG1_interact PF15898.5 CAM37099.1 - 7.6 7.5 21.0 4.1 8.4 17.0 2.7 2 1 1 3 3 2 0 cGMP-dependent protein kinase interacting domain Atg14 PF10186.9 CAM37099.1 - 7.7 5.5 17.7 2.1e+02 0.8 3.8 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4140 PF13600.6 CAM37099.1 - 9.6 6.7 17.2 0.7 10.4 3.8 3.5 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) FYVE_2 PF02318.16 CAM37101.1 - 0.22 11.8 11.3 0.43 10.8 11.3 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger ERCC4 PF02732.15 CAM37103.1 - 6.1e-14 52.5 0.0 1.1e-13 51.6 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain PIG-H PF10181.9 CAM37104.1 - 1.3e-10 41.0 0.3 2.2e-10 40.2 0.3 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component LRR_4 PF12799.7 CAM37106.1 - 5.7e-07 29.8 11.5 0.72 10.4 0.1 6.8 6 1 2 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM37106.1 - 6.6e-06 25.8 2.0 0.4 10.5 0.0 5.0 5 1 1 6 6 6 3 Leucine rich repeat RACo_linker PF17650.1 CAM37106.1 - 0.21 11.5 1.0 1.9 8.4 0.1 2.7 3 0 0 3 3 3 0 RACo linker region Hexapep PF00132.24 CAM37107.1 - 4.4e-15 54.7 4.7 0.00016 21.2 1.5 3.3 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CAM37107.1 - 0.00078 19.1 0.7 0.00078 19.1 0.7 2.5 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase Beta_helix PF13229.6 CAM37107.1 - 0.12 12.2 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 Right handed beta helix region Exo_endo_phos PF03372.23 CAM37109.1 - 1.2e-13 51.1 0.0 2.4e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CAM37109.1 - 0.18 11.7 0.0 0.59 10.0 0.0 1.9 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase ThiF PF00899.21 CAM37111.2 - 3.8e-47 160.7 0.5 3e-46 157.8 0.4 2.0 1 1 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 CAM37111.2 - 0.067 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.20 CAM37111.2 - 0.081 13.0 0.1 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase SepZ PF06066.11 CAM37111.2 - 0.14 12.4 3.5 3.9 7.8 0.2 2.7 2 0 0 2 2 2 0 SepZ ABC1 PF03109.16 CAM37112.2 - 1.9e-27 95.8 0.0 4.8e-27 94.5 0.0 1.7 2 0 0 2 2 2 1 ABC1 family APH PF01636.23 CAM37112.2 - 0.0015 18.5 3.7 0.0024 17.8 0.1 2.8 3 1 0 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.25 CAM37112.2 - 0.031 13.6 0.0 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 Protein kinase domain Ribosomal_L9_N PF01281.19 CAM37113.1 - 9.9e-07 28.2 0.0 1.7e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain JHY PF15261.6 CAM37115.1 - 3.5e-08 34.2 5.1 0.003 18.3 0.8 2.8 2 1 0 2 2 2 2 Jhy protein LEAP-2 PF07359.11 CAM37115.1 - 1.4 8.8 3.4 1.3 8.9 0.3 2.4 2 0 0 2 2 2 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Dicty_REP PF05086.12 CAM37115.1 - 5.6 4.8 4.2 7.7 4.4 4.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Amastin PF07344.11 CAM37117.1 - 2.5e-49 167.1 14.8 3.3e-49 166.7 14.8 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF4293 PF14126.6 CAM37117.1 - 0.11 12.7 10.4 0.22 11.8 10.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) Tmemb_170 PF10190.9 CAM37117.1 - 0.12 12.8 13.9 0.052 13.9 7.9 2.2 2 0 0 2 2 2 0 Putative transmembrane protein 170 Amastin PF07344.11 CAM37118.1 - 9.9e-50 168.4 14.5 1.2e-49 168.1 14.5 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF4293 PF14126.6 CAM37118.1 - 0.086 13.1 10.6 0.16 12.2 10.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) Tmemb_170 PF10190.9 CAM37118.1 - 1.6 9.1 15.9 0.091 13.1 7.7 2.3 2 1 0 2 2 2 0 Putative transmembrane protein 170 Amastin PF07344.11 CAM37119.1 - 1.7e-49 167.6 14.7 2.3e-49 167.2 14.7 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF4293 PF14126.6 CAM37119.1 - 0.087 13.1 10.8 0.17 12.1 10.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) Tmemb_170 PF10190.9 CAM37119.1 - 0.32 11.4 14.2 0.12 12.7 7.7 2.2 2 0 0 2 2 2 0 Putative transmembrane protein 170 Ribosomal_L2_C PF03947.18 CAM37120.1 - 1.6e-20 73.5 0.1 2.9e-20 72.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Sod_Fe_C PF02777.18 CAM37121.1 - 6.9e-36 122.5 0.5 1.3e-35 121.6 0.1 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CAM37121.1 - 8e-21 74.3 1.1 1.5e-20 73.4 0.7 1.7 1 1 1 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Isochorismatase PF00857.20 CAM37122.1 - 6.7e-13 49.2 0.0 2.8e-12 47.2 0.0 1.8 1 1 0 1 1 1 1 Isochorismatase family Isochorismatase PF00857.20 CAM37123.1 - 4.9e-09 36.6 0.1 4.9e-09 36.6 0.1 2.2 3 1 1 4 4 4 1 Isochorismatase family Isochorismatase PF00857.20 CAM37124.1 - 1.6e-11 44.7 0.1 6.1e-11 42.8 0.1 1.8 1 1 0 1 1 1 1 Isochorismatase family zf-Tim10_DDP PF02953.15 CAM37125.1 - 2.5e-11 43.0 0.4 4.5e-11 42.2 0.4 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 CAM37125.1 - 0.077 12.7 0.6 0.15 11.8 0.6 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Kelch_3 PF13415.6 CAM37128.2 - 0.24 11.7 1.2 0.86 10.0 0.1 2.4 2 0 0 2 2 2 0 Galactose oxidase, central domain WD40 PF00400.32 CAM37135.1 - 2.6e-24 85.0 15.7 4.7e-06 27.2 0.0 10.4 9 1 1 10 10 10 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM37135.1 - 1.1e-14 54.5 0.3 0.0021 18.3 0.0 6.1 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 CAM37135.1 - 7.9e-06 25.6 0.3 0.00084 19.0 0.1 3.3 2 1 0 2 2 2 1 PQQ-like domain BBS2_Mid PF14783.6 CAM37135.1 - 0.001 19.1 0.0 0.89 9.6 0.0 4.4 6 0 0 6 6 6 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 CAM37135.1 - 0.0031 16.2 5.4 1.6 7.2 0.0 4.4 3 2 1 4 4 4 2 Nucleoporin Nup120/160 PHTB1_N PF14727.6 CAM37135.1 - 0.052 12.9 0.1 2.7 7.3 0.0 3.2 3 1 0 3 3 3 0 PTHB1 N-terminus ANAPC3 PF12895.7 CAM37135.1 - 0.7 10.2 3.0 4.3 7.6 0.1 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 CAM37135.1 - 1.5 9.8 5.4 36 5.6 0.0 5.0 4 1 0 4 4 4 0 Tetratricopeptide repeat CDC45 PF02724.14 CAM37136.2 - 2.7 6.2 8.7 4.8 5.4 8.7 1.3 1 0 0 1 1 1 0 CDC45-like protein Linker_histone PF00538.19 CAM37137.2 - 0.058 13.8 0.1 0.27 11.6 0.0 2.1 2 0 0 2 2 2 0 linker histone H1 and H5 family Rad60-SLD PF11976.8 CAM37138.1 - 3e-25 87.8 0.1 3.7e-25 87.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CAM37138.1 - 7.2e-12 44.9 0.0 8.7e-12 44.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family HTH_41 PF14502.6 CAM37138.1 - 0.1 12.3 0.2 0.39 10.4 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain TUG-UBL1 PF11470.8 CAM37138.1 - 0.12 12.7 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 TUG ubiquitin-like domain GlgS PF08971.11 CAM37139.1 - 0.17 12.0 0.1 0.29 11.2 0.1 1.3 1 0 0 1 1 1 0 Glycogen synthesis protein TPR_9 PF13371.6 CAM37139.1 - 0.19 11.9 1.2 1.5 9.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Metal_resist PF13801.6 CAM37139.1 - 9.9 6.4 9.7 0.38 11.0 0.9 2.7 2 1 0 3 3 3 0 Heavy-metal resistance FAM199X PF15814.5 CAM37141.1 - 3.1 6.7 5.9 7.5 5.5 5.9 1.6 1 0 0 1 1 1 0 Protein family FAM199X Pribosyl_synth PF14572.6 CAM37142.1 - 5.6e-20 72.1 1.1 5.6e-20 72.1 1.1 2.4 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 CAM37142.1 - 9.6e-19 67.4 0.8 2.6e-18 66.0 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase SPX PF03105.19 CAM37142.1 - 3.7e-06 27.1 0.5 1.3e-05 25.4 0.2 1.8 2 0 0 2 2 2 1 SPX domain Pribosyltran PF00156.27 CAM37142.1 - 0.044 13.3 0.4 0.42 10.1 0.1 2.6 3 0 0 3 3 3 0 Phosphoribosyl transferase domain Pkinase_Tyr PF07714.17 CAM37143.1 - 0.0035 16.7 0.0 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase KCNQ2_u3 PF16642.5 CAM37143.1 - 0.0044 18.0 0.2 0.0044 18.0 0.2 3.9 5 0 0 5 5 5 1 Unstructured region on Potassium channel subunit alpha KvLQT2 Kelch_1 PF01344.25 CAM37143.1 - 0.0069 15.9 0.1 0.88 9.2 0.0 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 CAM37143.1 - 0.013 15.8 0.1 0.47 10.8 0.0 3.9 3 0 0 3 3 3 0 Galactose oxidase, central domain Pkinase_Tyr PF07714.17 CAM37144.2 - 0.0056 16.0 0.0 0.0089 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CAM37144.2 - 0.0074 15.7 0.0 0.012 15.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 CAM37145.1 - 2.2e-36 125.6 0.0 5.7e-13 48.8 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CAM37145.1 - 7.8e-16 58.1 0.0 3.5e-05 23.2 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase APH PF01636.23 CAM37145.1 - 0.016 15.1 1.5 0.84 9.5 0.0 3.4 3 1 0 3 3 3 0 Phosphotransferase enzyme family Complex1_LYR PF05347.15 CAM37146.1 - 0.0016 18.5 0.9 0.0098 15.9 0.8 2.2 2 0 0 2 2 2 1 Complex 1 protein (LYR family) CMAS PF02353.20 CAM37147.1 - 2.3e-74 250.1 0.5 3.3e-74 249.6 0.5 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 CAM37147.1 - 7.1e-18 65.1 0.0 1.7e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAM37147.1 - 6.8e-14 52.3 0.0 1.7e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAM37147.1 - 6.6e-12 45.6 0.0 1.2e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAM37147.1 - 7.5e-09 36.2 0.0 2.9e-08 34.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 CAM37147.1 - 5e-06 26.2 0.0 2.9e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 CAM37147.1 - 5.2e-06 26.3 0.0 1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 CAM37147.1 - 0.00033 20.3 0.0 0.00052 19.7 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) MetW PF07021.12 CAM37147.1 - 0.00068 19.3 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 CAM37147.1 - 0.00099 19.1 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 CAM37147.1 - 0.0016 17.6 0.0 0.0028 16.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase FtsJ PF01728.19 CAM37147.1 - 0.0024 18.0 0.0 0.0038 17.4 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 CAM37147.1 - 0.0039 16.6 0.0 0.007 15.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 CAM37147.1 - 0.004 16.9 0.0 0.0073 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.14 CAM37147.1 - 0.0085 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB eIF-5_eIF-2B PF01873.17 CAM37148.1 - 3.4e-29 101.1 0.7 6.8e-29 100.1 0.7 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Cytochrom_c3_2 PF14537.6 CAM37148.1 - 0.056 13.9 0.4 0.21 12.1 0.4 2.0 1 0 0 1 1 1 0 Cytochrome c3 Img2 PF05046.14 CAM37149.1 - 2.3e-05 24.6 0.0 4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) PRIMA1 PF16101.5 CAM37150.2 - 0.0076 16.3 0.5 0.014 15.4 0.5 1.4 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 Mtp PF03821.16 CAM37151.1 - 0.0069 16.0 0.0 0.0096 15.5 0.0 1.2 1 0 0 1 1 1 1 Golgi 4-transmembrane spanning transporter PRIMA1 PF16101.5 CAM37151.1 - 0.05 13.6 0.1 0.079 13.0 0.1 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF5134 PF17197.4 CAM37151.1 - 0.067 13.1 0.5 0.12 12.3 0.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5134) TMEM154 PF15102.6 CAM37151.1 - 0.12 12.3 0.2 0.97 9.3 0.0 2.0 1 1 1 2 2 2 0 TMEM154 protein family AAA_16 PF13191.6 CAM37153.1 - 4.4e-06 27.2 0.7 2.3e-05 24.9 0.2 2.5 2 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 CAM37153.1 - 0.0037 16.5 0.2 0.14 11.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 CAM37153.1 - 0.0037 17.3 0.0 0.0066 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CAM37153.1 - 0.0048 17.2 0.1 0.018 15.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 CAM37153.1 - 0.007 16.3 0.0 0.019 14.9 0.0 1.7 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 CAM37153.1 - 0.044 13.5 0.0 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA PF00004.29 CAM37153.1 - 0.092 13.2 0.0 0.29 11.6 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CAM37154.1 - 0.0033 17.7 0.1 0.069 13.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CAM37154.1 - 0.0056 17.1 0.0 0.0056 17.1 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 CAM37154.1 - 0.033 14.7 0.7 0.13 12.8 0.0 2.3 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.12 CAM37154.1 - 0.036 13.3 0.0 0.079 12.2 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Glutaredoxin PF00462.24 CAM37154.1 - 0.074 13.3 0.0 0.25 11.6 0.0 1.9 1 0 0 1 1 1 0 Glutaredoxin DUF815 PF05673.13 CAM37154.1 - 0.099 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA PF00004.29 CAM37154.1 - 0.1 13.0 0.0 0.29 11.5 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF5563 PF17718.1 CAM37154.1 - 0.12 11.9 0.2 0.19 11.3 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5563) ATPase_2 PF01637.18 CAM37154.1 - 0.12 12.2 0.0 0.35 10.8 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ICMT PF04140.14 CAM37154.1 - 0.14 12.6 0.0 0.33 11.4 0.0 1.6 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family TsaE PF02367.17 CAM37154.1 - 0.18 11.8 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Amastin PF07344.11 CAM37155.1 - 9.7e-55 184.7 11.0 1.2e-54 184.4 11.0 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.20 CAM37155.1 - 0.0012 18.8 7.2 0.0017 18.3 7.2 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Phage_holin_3_6 PF07332.11 CAM37155.1 - 0.017 15.2 0.9 0.017 15.2 0.9 2.8 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Amastin PF07344.11 CAM37156.1 - 7.3e-44 149.3 11.1 8.5e-44 149.1 11.1 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein RVT_1 PF00078.27 CAM37158.2 - 7.8e-21 74.6 0.0 1.3e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FYVE PF01363.21 CAM37158.2 - 5.6 7.2 5.2 1.2 9.3 0.0 2.5 3 0 0 3 3 3 0 FYVE zinc finger DNA_pol_B_thumb PF14791.6 CAM37159.1 - 9e-21 73.8 0.0 1.9e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 CAM37159.1 - 1.3e-17 64.0 0.0 3.1e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 CAM37159.1 - 7.4e-15 55.1 0.4 3.9e-13 49.6 0.1 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 CAM37159.1 - 2.8e-13 49.5 0.1 2.6e-12 46.4 0.0 2.6 3 0 0 3 3 3 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.6 CAM37159.1 - 7.7e-06 26.4 0.9 0.0021 18.6 0.0 2.8 1 1 2 3 3 3 2 Helix-hairpin-helix domain HHH_3 PF12836.7 CAM37159.1 - 0.016 15.5 0.1 3.3 8.0 0.0 2.9 2 1 1 3 3 3 0 Helix-hairpin-helix motif DMP12 PF16779.5 CAM37159.1 - 0.041 13.9 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 DNA-mimic protein IMS_HHH PF11798.8 CAM37159.1 - 0.14 12.6 0.0 28 5.3 0.0 2.7 2 0 0 2 2 2 0 IMS family HHH motif DNA_pol_B_palm PF14792.6 CAM37160.1 - 1.1e-25 90.0 0.0 2.9e-25 88.7 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 CAM37160.1 - 2.1e-15 56.6 0.9 7e-14 51.8 0.5 3.3 2 1 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 CAM37160.1 - 8.3e-08 31.9 0.1 5.9e-07 29.2 0.1 2.3 1 1 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 CAM37160.1 - 0.00075 19.8 0.5 2 8.9 0.0 4.1 4 0 0 4 4 4 1 Helix-hairpin-helix domain HHH_5 PF14520.6 CAM37160.1 - 0.0037 17.8 1.1 0.03 14.9 0.0 3.0 3 0 0 3 3 3 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 CAM37160.1 - 0.027 14.8 0.0 0.06 13.6 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain Lactamase_B_4 PF13691.6 CAM37161.2 - 3e-05 23.6 0.0 0.0001 21.9 0.0 1.9 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 CAM37161.2 - 0.0029 17.2 0.4 0.025 14.1 0.1 2.4 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CAM37161.2 - 0.11 12.5 2.4 0.22 11.5 0.4 2.5 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Pkinase PF00069.25 CAM37163.2 - 4.9e-60 203.1 0.0 8.1e-60 202.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM37163.2 - 3.1e-42 144.7 0.0 4.6e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM37163.2 - 3.5e-05 23.2 0.0 5.3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CAM37163.2 - 5.7e-05 23.2 1.0 0.037 13.9 0.1 2.8 1 1 0 2 2 2 2 Phosphotransferase enzyme family PKS_DE PF18369.1 CAM37163.2 - 1.9 9.1 5.3 0.33 11.6 0.5 2.2 2 0 0 2 2 2 0 Polyketide synthase dimerisation element domain Dpy-30 PF05186.13 CAM37166.1 - 1.4e-07 31.1 0.7 4.5e-07 29.4 0.1 2.1 2 0 0 2 2 2 1 Dpy-30 motif DUF2924 PF11149.8 CAM37166.1 - 7.4 7.0 8.8 1.5 9.2 2.9 2.9 2 1 2 4 4 4 0 Protein of unknown function (DUF2924) TMEM65 PF10507.9 CAM37167.2 - 4.5e-29 100.6 0.8 4.5e-29 100.6 0.8 2.5 2 0 0 2 2 2 1 Transmembrane protein 65 CaM_binding PF07839.11 CAM37167.2 - 2 9.2 5.3 0.75 10.6 1.2 2.1 2 0 0 2 2 2 0 Plant calmodulin-binding domain AAA_5 PF07728.14 CAM37168.1 - 6.3e-83 275.7 0.0 4.9e-32 110.8 0.0 3.7 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CAM37168.1 - 2.1e-07 31.5 1.0 0.016 15.6 0.0 4.4 4 0 0 4 4 3 2 AAA ATPase domain AAA_7 PF12775.7 CAM37168.1 - 2.5e-05 23.9 0.1 0.024 14.2 0.1 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA PF00004.29 CAM37168.1 - 3.9e-05 24.1 0.1 0.18 12.2 0.0 3.1 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 CAM37168.1 - 4.7e-05 23.4 0.1 0.019 14.9 0.1 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 CAM37168.1 - 0.00015 22.0 0.6 0.067 13.5 0.1 3.4 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 CAM37168.1 - 0.00023 21.0 0.0 0.13 12.0 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_3 PF07726.11 CAM37168.1 - 0.00037 20.4 0.0 0.17 11.7 0.0 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 CAM37168.1 - 0.0017 18.0 0.0 0.72 9.6 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain Sigma54_activat PF00158.26 CAM37168.1 - 0.0055 16.4 0.1 4.6 6.9 0.0 3.4 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_18 PF13238.6 CAM37168.1 - 0.0097 16.4 0.0 0.67 10.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain VWA_2 PF13519.6 CAM37168.1 - 0.01 16.5 0.0 0.04 14.6 0.0 2.1 1 0 0 1 1 1 0 von Willebrand factor type A domain VWA PF00092.28 CAM37168.1 - 0.011 16.0 0.0 0.026 14.8 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain AAA_2 PF07724.14 CAM37168.1 - 0.015 15.4 0.0 2.5 8.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Rad17 PF03215.15 CAM37168.1 - 0.023 14.6 0.0 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain Mg_chelatase PF01078.21 CAM37168.1 - 0.023 14.1 1.2 1.2 8.5 0.1 3.3 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI TniB PF05621.11 CAM37168.1 - 0.024 14.0 0.0 7.4 5.9 0.0 2.7 2 0 0 2 2 2 0 Bacterial TniB protein DUF815 PF05673.13 CAM37168.1 - 0.033 13.4 0.1 2.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RuvB_N PF05496.12 CAM37168.1 - 0.091 12.5 0.0 3.6 7.3 0.0 2.6 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 CAM37168.1 - 0.099 13.2 0.0 2.2 8.8 0.0 2.8 2 0 0 2 2 2 0 ABC transporter DUF615 PF04751.14 CAM37168.1 - 0.43 10.6 4.2 0.14 12.1 0.7 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF615) Peptidase_C1 PF00112.23 CAM37169.1 - 1.4e-71 241.1 1.5 2.7e-71 240.1 1.5 1.5 1 0 0 1 1 1 1 Papain family cysteine protease DUF3586 PF12131.8 CAM37169.1 - 5e-29 100.4 13.2 1.1e-28 99.3 13.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3586) Inhibitor_I29 PF08246.12 CAM37169.1 - 2.2e-11 44.0 2.6 3.8e-11 43.3 2.6 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CAM37169.1 - 3.2e-06 26.2 0.5 0.00052 18.9 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 CAM37170.1 - 1.7e-71 240.8 1.7 3.4e-71 239.8 1.7 1.5 1 0 0 1 1 1 1 Papain family cysteine protease DUF3586 PF12131.8 CAM37170.1 - 2.3e-29 101.4 12.0 2.3e-29 101.4 12.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3586) Inhibitor_I29 PF08246.12 CAM37170.1 - 2.2e-11 44.0 2.6 3.8e-11 43.3 2.6 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CAM37170.1 - 5.8e-06 25.3 0.5 0.00087 18.2 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 CAM37171.1 - 1.5e-71 241.0 1.6 2.9e-71 240.0 1.6 1.5 1 0 0 1 1 1 1 Papain family cysteine protease DUF3586 PF12131.8 CAM37171.1 - 1.1e-28 99.3 13.2 1.1e-28 99.3 13.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3586) Inhibitor_I29 PF08246.12 CAM37171.1 - 2.2e-11 44.0 2.6 3.8e-11 43.3 2.6 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CAM37171.1 - 3.4e-06 26.1 0.5 0.00052 18.9 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family DUF4199 PF13858.6 CAM37173.1 - 0.017 15.5 0.1 0.019 15.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Polysacc_synt PF01943.17 CAM37173.1 - 0.02 14.3 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Saf_2TM PF18303.1 CAM37173.1 - 0.021 14.4 0.0 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain OATP PF03137.20 CAM37173.1 - 0.029 12.7 0.0 0.033 12.5 0.0 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family TssO PF17561.2 CAM37173.1 - 0.06 13.4 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssO DUF1279 PF06916.13 CAM37173.1 - 0.066 13.8 0.1 0.091 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) MAP17 PF15807.5 CAM37173.1 - 0.086 13.1 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 zf-RING_2 PF13639.6 CAM37174.1 - 4e-08 33.5 7.9 4e-08 33.5 7.9 4.0 4 0 0 4 4 4 2 Ring finger domain zf-C3HC4_2 PF13923.6 CAM37174.1 - 0.002 18.0 6.7 0.002 18.0 6.7 5.0 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CAM37174.1 - 0.0076 16.2 6.7 0.0076 16.2 6.7 4.2 4 1 0 4 4 4 1 zinc-RING finger domain zf-RING_11 PF17123.5 CAM37174.1 - 0.014 15.1 9.8 0.014 15.1 9.8 3.2 3 0 0 3 3 3 0 RING-like zinc finger zf-C3HC4 PF00097.25 CAM37174.1 - 0.017 15.0 7.3 0.017 15.0 7.3 4.8 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H PF13771.6 CAM37174.1 - 0.035 14.4 2.7 0.035 14.4 2.7 4.2 2 1 2 4 4 4 0 PHD-like zinc-binding domain DUF4684 PF15736.5 CAM37175.1 - 0.015 14.0 2.1 0.022 13.4 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4684) CdiI_2 PF18593.1 CAM37175.1 - 0.081 13.6 0.3 3.2 8.5 0.0 3.0 3 0 0 3 3 3 0 CdiI immunity protein TPR_1 PF00515.28 CAM37176.1 - 1.5e-51 170.2 33.4 1.3e-07 31.1 0.0 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 CAM37176.1 - 5.1e-43 141.7 31.1 4.4e-05 23.3 0.0 9.6 9 0 0 9 9 9 9 Tetratricopeptide repeat STI1 PF17830.1 CAM37176.1 - 5.1e-29 100.0 5.3 7.3e-15 54.6 1.4 3.5 3 0 0 3 3 3 2 STI1 domain TPR_11 PF13414.6 CAM37176.1 - 5.2e-28 96.5 26.9 7.8e-07 28.7 0.3 8.5 6 1 2 8 8 8 7 TPR repeat TPR_8 PF13181.6 CAM37176.1 - 1.1e-21 75.2 25.4 0.00062 19.8 0.0 9.0 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_12 PF13424.6 CAM37176.1 - 1.2e-19 70.3 21.1 5.4e-07 29.8 0.3 7.4 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 CAM37176.1 - 1.5e-17 63.9 6.0 0.083 13.4 0.2 6.7 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 CAM37176.1 - 4.1e-16 58.3 9.6 0.18 12.7 0.0 9.3 5 3 5 10 10 9 2 Tetratricopeptide repeat TPR_16 PF13432.6 CAM37176.1 - 7.4e-16 58.5 9.0 0.00031 21.3 0.1 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 CAM37176.1 - 6.1e-11 41.9 15.6 0.25 11.8 0.3 8.1 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 CAM37176.1 - 8.1e-10 38.7 1.3 0.00028 21.0 0.0 4.8 5 2 1 7 7 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 CAM37176.1 - 1.8e-09 37.0 12.9 0.33 11.1 0.0 8.6 8 1 1 9 9 8 2 Tetratricopeptide repeat TPR_10 PF13374.6 CAM37176.1 - 2.2e-08 33.7 18.9 0.015 15.1 0.0 8.8 10 0 0 10 10 9 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CAM37176.1 - 2.3e-07 30.8 3.0 1.1 9.4 0.0 6.1 7 0 0 7 7 7 2 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 CAM37176.1 - 0.0001 22.4 24.8 0.091 13.0 4.5 6.2 4 2 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 CAM37176.1 - 0.00075 19.5 23.3 0.32 11.1 0.2 7.8 7 1 1 8 8 8 2 MIT (microtubule interacting and transport) domain TPR_20 PF14561.6 CAM37176.1 - 0.00098 19.4 2.6 1.9 8.9 0.0 4.4 4 1 0 4 4 4 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 CAM37176.1 - 0.0027 17.1 8.8 1.1 8.8 0.0 5.4 7 0 0 7 7 5 1 SHNi-TPR TPR_6 PF13174.6 CAM37176.1 - 0.0039 17.7 25.0 2.7 8.8 0.1 8.9 9 0 0 9 9 9 1 Tetratricopeptide repeat DUF3856 PF12968.7 CAM37176.1 - 0.019 15.0 9.5 5.6 7.0 0.5 5.4 3 3 2 5 5 5 0 Domain of Unknown Function (DUF3856) TPR_3 PF07720.12 CAM37176.1 - 0.056 13.5 23.2 0.099 12.7 0.5 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat BTAD PF03704.17 CAM37176.1 - 0.067 13.6 7.5 0.94 9.9 0.6 4.7 3 2 1 5 5 5 0 Bacterial transcriptional activator domain TPM_phosphatase PF04536.14 CAM37176.1 - 0.068 13.3 1.4 2.5 8.3 0.1 3.6 3 0 0 3 3 3 0 TPM domain FAM165 PF14981.6 CAM37176.1 - 0.072 12.9 0.3 0.27 11.1 0.3 2.0 1 0 0 1 1 1 0 FAM165 family DnaI_N PF07319.11 CAM37176.1 - 0.14 12.8 2.5 4.5 8.0 0.0 4.0 4 1 1 5 5 3 0 Primosomal protein DnaI N-terminus DUF5113 PF17140.4 CAM37176.1 - 2 8.2 11.6 48 3.7 0.1 5.2 2 2 4 6 6 6 0 Domain of unknown function (DUF5113) RPN7 PF10602.9 CAM37176.1 - 3.2 7.4 9.8 0.32 10.7 0.7 3.3 1 1 2 3 3 3 0 26S proteasome subunit RPN7 Pribosyltran_N PF13793.6 CAM37178.1 - 8.4e-36 122.4 0.1 1.8e-35 121.4 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CAM37178.1 - 1.2e-22 80.8 0.6 5.1e-22 78.8 0.3 2.0 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CAM37178.1 - 1e-18 67.4 0.4 1.9e-18 66.5 0.4 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CAM37178.1 - 0.005 16.3 0.1 0.0088 15.5 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Sec3_C PF09763.9 CAM37180.1 - 2.3e-77 261.0 0.0 1e-76 258.9 0.0 1.9 1 1 0 1 1 1 1 Exocyst complex component Sec3 DUF812 PF05667.11 CAM37180.1 - 0.00033 19.7 1.5 0.00052 19.0 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) POX PF07526.11 CAM37180.1 - 0.012 16.2 0.8 2 9.0 0.7 3.0 2 0 0 2 2 2 0 Associated with HOX Vps54_N PF10475.9 CAM37180.1 - 0.017 14.4 5.3 0.033 13.5 5.3 1.4 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex VP4_helical PF17478.2 CAM37180.1 - 0.11 11.9 0.4 0.62 9.4 0.1 2.1 2 0 0 2 2 2 0 Rotavirus VP4 helical domain THOC7 PF05615.13 CAM37180.1 - 0.12 12.7 8.1 0.49 10.7 8.1 2.0 1 0 0 1 1 1 0 Tho complex subunit 7 Mce4_CUP1 PF11887.8 CAM37180.1 - 0.26 10.7 1.6 0.48 9.8 1.6 1.4 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative YabA PF06156.13 CAM37180.1 - 0.46 11.1 2.3 1.4 9.6 2.3 1.8 1 0 0 1 1 1 0 Initiation control protein YabA Exonuc_VII_L PF02601.15 CAM37180.1 - 0.87 9.1 6.3 2 7.9 6.3 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit TPMT PF05724.11 CAM37181.1 - 4.8e-17 62.4 0.0 1e-16 61.3 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 CAM37181.1 - 0.00038 20.3 0.0 0.00059 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAM37181.1 - 0.0078 16.9 0.0 0.015 15.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain mTERF PF02536.14 CAM37182.1 - 4.6e-06 25.8 0.0 0.00014 20.9 0.0 2.0 1 1 1 2 2 2 2 mTERF FAST_1 PF06743.15 CAM37182.1 - 0.021 14.7 0.1 8.8 6.4 0.0 3.5 2 1 1 3 3 3 0 FAST kinase-like protein, subdomain 1 Slu7 PF11708.8 CAM37183.1 - 0.00048 20.0 7.1 0.00048 20.0 7.1 2.7 3 1 1 4 4 4 1 Pre-mRNA splicing Prp18-interacting factor BTK PF00779.19 CAM37183.1 - 0.0023 17.7 2.5 0.0048 16.7 2.5 1.5 1 0 0 1 1 1 1 BTK motif zf-CCHC_5 PF14787.6 CAM37183.1 - 0.063 13.0 1.8 0.12 12.1 1.8 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger tRNA-synt_1c PF00749.21 CAM37183.1 - 0.11 11.4 0.2 0.18 10.6 0.2 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain zf-CCHC PF00098.23 CAM37183.1 - 0.22 11.6 2.5 0.46 10.7 2.5 1.6 1 0 0 1 1 1 0 Zinc knuckle ANAPC4_WD40 PF12894.7 CAM37184.1 - 2.5e-12 46.9 1.4 7.1e-06 26.2 0.0 5.8 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 CAM37184.1 - 1.4e-10 40.8 2.5 0.0025 17.0 0.1 4.7 5 0 0 5 5 5 2 Coatomer WD associated region TPR_7 PF13176.6 CAM37184.1 - 0.00023 21.0 6.0 0.067 13.3 0.3 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat eIF2A PF08662.11 CAM37184.1 - 0.0074 16.2 0.1 0.18 11.7 0.0 2.6 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 CAM37184.1 - 0.0093 16.8 12.9 0.75 10.8 0.0 6.3 7 0 0 7 7 6 1 WD domain, G-beta repeat Clathrin PF00637.20 CAM37184.1 - 0.021 14.7 8.8 1.2 9.1 0.2 4.4 3 1 2 5 5 5 0 Region in Clathrin and VPS zf-RanBP PF00641.18 CAM37184.1 - 0.034 13.5 12.3 0.038 13.3 4.2 2.7 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Vps39_1 PF10366.9 CAM37184.1 - 0.062 13.6 0.3 0.21 11.9 0.3 1.9 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 RPN7 PF10602.9 CAM37184.1 - 0.35 10.5 2.7 3.7 7.2 0.1 3.1 1 1 1 3 3 3 0 26S proteasome subunit RPN7 TPR_12 PF13424.6 CAM37184.1 - 0.59 10.5 18.3 0.42 10.9 0.5 4.5 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 CAM37184.1 - 0.72 10.8 14.1 0.14 13.0 0.8 4.4 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CAM37184.1 - 1.1 9.5 18.8 0.7 10.2 1.2 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 CAM37184.1 - 1.7 9.4 10.6 26 5.6 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CAM37184.1 - 2.5 8.9 3.9 12 6.8 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat MIX PF18529.1 CAM37185.1 - 2.1e-94 313.2 1.0 2.5e-94 313.0 1.0 1.0 1 0 0 1 1 1 1 Mitochondrial membrane-anchored proteins DUF688 PF05097.12 CAM37186.1 - 0.0066 15.7 4.1 0.014 14.6 4.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF688) Sec62 PF03839.16 CAM37186.1 - 6.6 6.2 5.7 13 5.2 5.7 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 Amastin PF07344.11 CAM37187.1 - 4.7e-56 188.9 8.9 5.5e-56 188.7 8.9 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Amastin PF07344.11 CAM37189.1 - 0.00012 22.0 5.9 0.00012 22.0 5.9 1.9 2 0 0 2 2 2 1 Amastin surface glycoprotein Pox_A14 PF05767.12 CAM37189.1 - 0.054 13.7 0.4 0.054 13.7 0.4 2.0 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 DnaJ PF00226.31 CAM37190.1 - 1.2e-15 57.3 1.0 2.4e-15 56.4 1.0 1.5 1 0 0 1 1 1 1 DnaJ domain Amastin PF07344.11 CAM37191.1 - 9.3e-44 149.0 16.8 1.2e-43 148.7 16.8 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Amastin PF07344.11 CAM37192.1 - 4.9e-43 146.6 16.2 4.9e-43 146.6 16.2 1.8 2 0 0 2 2 2 1 Amastin surface glycoprotein Amastin PF07344.11 CAM37193.1 - 7.6e-47 159.0 10.6 9e-47 158.8 10.6 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Amastin PF07344.11 CAM37194.1 - 1.3e-49 168.0 10.4 1.6e-49 167.7 10.4 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Phage_holin_3_6 PF07332.11 CAM37194.1 - 1.8 8.6 13.6 1.7 8.7 5.0 2.9 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Amastin PF07344.11 CAM37196.1 - 5.9e-54 182.1 13.7 7.1e-54 181.8 13.7 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein SUR7 PF06687.12 CAM37196.1 - 0.014 15.0 15.2 0.037 13.6 2.0 3.1 3 0 0 3 3 3 0 SUR7/PalI family DUF4220 PF13968.6 CAM37196.1 - 0.42 10.0 5.2 0.041 13.3 1.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4220) Amastin PF07344.11 CAM37197.1 - 1.7e-53 180.6 14.0 2.1e-53 180.3 14.0 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein SUR7 PF06687.12 CAM37197.1 - 0.0071 16.0 15.3 0.022 14.4 1.3 3.1 3 0 0 3 3 3 2 SUR7/PalI family DUF2339 PF10101.9 CAM37197.1 - 1.5 7.3 15.2 0.38 9.3 2.5 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2339) DUF2165 PF09933.9 CAM37197.1 - 2.8 8.0 8.3 0.22 11.5 0.3 2.4 2 1 1 3 3 3 0 Predicted small integral membrane protein (DUF2165) DUF2976 PF11190.8 CAM37197.1 - 7.7 6.4 11.5 0.082 12.7 2.3 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2976) Amastin PF07344.11 CAM37198.1 - 3e-54 183.1 13.8 3.5e-54 182.9 13.8 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.6 CAM37198.1 - 3.4 7.4 12.6 0.2 11.4 4.2 2.4 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.11 CAM37199.1 - 6.2e-54 182.0 14.7 7.3e-54 181.8 14.7 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Amastin PF07344.11 CAM37200.1 - 8.1e-44 149.2 15.8 9.6e-44 148.9 15.8 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein FA_desaturase PF00487.24 CAM37203.1 - 1.3e-26 94.0 25.8 1.3e-26 94.0 25.8 1.7 1 1 1 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.8 CAM37203.1 - 0.05 13.8 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) BT1 PF03092.16 CAM37204.1 - 3.7e-191 635.9 14.2 4.4e-191 635.7 14.2 1.0 1 0 0 1 1 1 1 BT1 family PHO4 PF01384.20 CAM37205.1 - 4.4e-111 371.2 17.7 5.3e-111 370.9 17.7 1.1 1 0 0 1 1 1 1 Phosphate transporter family MMS19_N PF14500.6 CAM37207.1 - 3.9e-43 147.9 6.3 1e-42 146.5 5.1 2.2 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II CLASP_N PF12348.8 CAM37207.1 - 0.011 15.4 0.4 0.011 15.4 0.4 2.1 2 1 0 2 2 2 0 CLASP N terminal Thymidylate_kin PF02223.17 CAM37208.1 - 2.3e-13 50.3 0.0 7.7e-13 48.5 0.0 1.9 1 1 0 1 1 1 1 Thymidylate kinase Ribosomal_L35Ae PF01247.18 CAM37209.1 - 1.1e-33 115.2 0.9 1.8e-33 114.6 0.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 CAM37209.1 - 5e-06 26.6 0.4 0.056 13.7 0.0 2.4 2 1 0 2 2 2 2 RimM N-terminal domain DUF4115 PF13464.6 CAM37209.1 - 0.036 14.3 0.0 0.075 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4115) adh_short PF00106.25 CAM37211.1 - 1.7e-27 96.2 0.0 4.5e-24 85.0 0.0 2.3 1 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CAM37211.1 - 8e-20 71.4 0.0 4.8e-16 59.0 0.0 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CAM37211.1 - 0.0015 18.5 0.2 0.0033 17.4 0.0 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 CAM37211.1 - 0.0064 16.0 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family SRP40_C PF05022.12 CAM37212.1 - 9.2e-13 48.9 1.2 2.7e-12 47.3 0.9 2.0 2 0 0 2 2 2 1 SRP40, C-terminal domain SPESP1 PF15754.5 CAM37212.1 - 0.02 14.1 4.6 0.03 13.5 4.6 1.1 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 WD40 PF00400.32 CAM37213.2 - 2e-30 104.4 28.3 3.4e-07 30.8 0.6 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM37213.2 - 1.1e-05 25.6 0.3 0.0049 17.1 0.0 4.1 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Seryl_tRNA_N PF02403.22 CAM37215.2 - 0.3 11.3 11.0 0.26 11.5 5.7 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Pex19 PF04614.12 CAM37215.2 - 1.9 8.2 10.6 0.34 10.7 5.5 2.0 2 0 0 2 2 2 0 Pex19 protein family SKA2 PF16740.5 CAM37215.2 - 2.5 7.9 11.7 2.6 7.9 0.6 3.2 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 2 FlxA PF14282.6 CAM37215.2 - 3.2 7.8 12.2 5.8 7.0 7.5 2.7 1 1 1 2 2 2 0 FlxA-like protein Helicase_C PF00271.31 CAM37216.2 - 6.8e-13 48.9 0.2 2.5e-12 47.1 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CAM37216.2 - 3.6e-11 43.1 0.2 1e-08 35.2 0.0 2.6 3 0 0 3 3 3 2 DEAD/DEAH box helicase Secretin_N PF03958.17 CAM37216.2 - 0.016 15.6 0.2 5.3 7.5 0.0 3.1 2 1 0 2 2 2 0 Bacterial type II/III secretion system short domain DUF2046 PF09755.9 CAM37218.1 - 0.0087 15.3 31.7 0.025 13.8 22.1 3.1 2 1 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) DUF1943 PF09172.11 CAM37218.1 - 0.59 9.3 4.4 2.8 7.1 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) Exonuc_VII_L PF02601.15 CAM37218.1 - 0.7 9.4 24.8 2.4 7.7 2.1 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit NIBRIN_BRCT_II PF16508.5 CAM37218.1 - 1.8 8.9 5.0 0.71 10.2 1.3 2.0 2 0 0 2 2 2 0 Second BRCT domain on Nijmegen syndrome breakage protein CENP-K PF11802.8 CAM37218.1 - 4.6 6.7 25.8 4.5 6.8 2.2 2.2 2 0 0 2 2 2 0 Centromere-associated protein K Baculo_PP31 PF05311.11 CAM37218.1 - 5.9 6.3 9.7 0.47 9.9 1.3 2.3 2 1 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) Ribosomal_S15 PF00312.22 CAM37218.1 - 8.7 6.6 12.3 0.44 10.8 5.6 2.3 2 1 0 2 2 2 0 Ribosomal protein S15 HI0933_like PF03486.14 CAM37218.1 - 9.8 4.8 8.9 5.6 5.6 0.3 2.2 2 0 0 2 2 2 0 HI0933-like protein GDA1_CD39 PF01150.17 CAM37219.1 - 1e-63 215.5 0.0 3.5e-63 213.7 0.0 1.7 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 CAM37219.1 - 0.056 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Ppx/GppA phosphatase family LRR_8 PF13855.6 CAM37220.2 - 6.7e-13 48.2 11.1 4.6e-08 32.7 7.6 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CAM37220.2 - 1.4e-12 47.6 7.5 1.6e-05 25.1 0.4 3.3 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CAM37220.2 - 3.5e-07 29.8 7.8 2.2 9.1 0.6 5.8 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_9 PF14580.6 CAM37220.2 - 0.069 12.6 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Leucine-rich repeat PDZ_6 PF17820.1 CAM37221.1 - 1.8e-10 40.5 0.1 4.7e-10 39.2 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CAM37221.1 - 1.3e-06 28.7 0.0 2.8e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CAM37221.1 - 1.9e-06 28.1 0.0 7.6e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 PDZ domain Pkinase PF00069.25 CAM37222.1 - 7.8e-59 199.2 0.0 1e-58 198.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM37222.1 - 2.2e-28 99.3 0.0 4.1e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CAM37222.1 - 9.5e-08 31.4 0.1 1.4e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CAM37222.1 - 1.3e-05 24.6 0.7 2.9e-05 23.5 0.7 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CAM37222.1 - 9e-05 22.5 0.5 0.00016 21.7 0.5 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CAM37222.1 - 0.029 14.0 1.4 0.21 11.2 0.4 2.4 2 0 0 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 CAM37222.1 - 0.032 13.0 0.6 0.056 12.2 0.6 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 CAM37222.1 - 0.05 12.9 0.0 0.11 11.7 0.0 1.7 1 1 0 1 1 1 0 Kinase-like Nop PF01798.18 CAM37223.1 - 5.2e-79 264.9 0.0 7e-79 264.5 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CAM37223.1 - 2.8e-16 59.6 0.0 9.8e-16 57.9 0.0 2.0 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Amastin PF07344.11 CAM37226.1 - 1.4e-37 129.0 21.0 7.8e-25 87.5 6.8 2.4 2 1 0 2 2 2 2 Amastin surface glycoprotein Vma12 PF11712.8 CAM37226.1 - 1.4 9.0 0.0 1.4 9.0 0.0 2.7 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase PglL_A PF15864.5 CAM37226.1 - 1.6 8.5 5.6 14 5.6 0.5 3.1 2 0 0 2 2 2 0 Protein glycosylation ligase Amastin PF07344.11 CAM37227.1 - 3e-42 144.1 26.0 6.3e-26 91.1 15.6 2.3 2 0 0 2 2 2 2 Amastin surface glycoprotein Lysis_col PF02402.16 CAM37227.1 - 0.0021 17.7 0.0 0.01 15.5 0.0 2.2 1 0 0 1 1 1 1 Lysis protein TadE PF07811.12 CAM37227.1 - 0.034 14.4 2.0 0.034 14.4 2.0 3.0 3 0 0 3 3 3 0 TadE-like protein CaM_binding PF07839.11 CAM37228.2 - 1.5 9.6 10.2 0.5 11.1 4.8 2.6 2 0 0 2 2 2 0 Plant calmodulin-binding domain Pterin_4a PF01329.19 CAM37229.1 - 1.3e-08 34.9 0.0 5.7e-08 32.8 0.0 2.1 2 1 0 2 2 2 1 Pterin 4 alpha carbinolamine dehydratase COPI_assoc PF08507.10 CAM37230.2 - 1.6e-10 41.1 12.8 1.9e-10 40.9 12.8 1.0 1 0 0 1 1 1 1 COPI associated protein RNase_T PF00929.24 CAM37231.1 - 3e-09 37.6 0.0 4.8e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Exonuclease CCDC106 PF15794.5 CAM37232.2 - 0.44 10.2 4.6 0.13 12.0 0.2 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 DUF4200 PF13863.6 CAM37232.2 - 0.81 10.1 9.1 1.3 9.4 1.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Iso_dh PF00180.20 CAM37233.1 - 3.3e-72 243.5 0.0 3.8e-72 243.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase FAM193_C PF15914.5 CAM37233.1 - 0.056 13.2 1.0 1.5 8.6 0.0 2.9 3 0 0 3 3 3 0 FAM193 family C-terminal Vps5 PF09325.10 CAM37234.1 - 0.048 13.2 7.1 0.084 12.4 7.1 1.3 1 0 0 1 1 1 0 Vps5 C terminal like DUF3584 PF12128.8 CAM37234.1 - 0.078 10.5 13.0 0.11 10.0 13.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2615 PF11027.8 CAM37234.1 - 0.12 12.5 0.3 7.8 6.7 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) UPF0242 PF06785.11 CAM37234.1 - 0.52 10.4 10.7 1.1 9.3 10.7 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Fmp27_WPPW PF10359.9 CAM37234.1 - 0.93 8.3 6.8 1.5 7.5 6.8 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Allexi_40kDa PF05549.11 CAM37234.1 - 1.8 8.0 5.7 3.6 7.0 5.2 1.8 1 1 0 1 1 1 0 Allexivirus 40kDa protein SlyX PF04102.12 CAM37234.1 - 2.5 8.8 21.2 0.042 14.5 8.2 4.1 4 0 0 4 4 4 0 SlyX Corona_S2 PF01601.16 CAM37234.1 - 4.2 5.7 4.4 6 5.2 4.4 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Spc24 PF08286.11 CAM37234.1 - 8.4 6.7 8.8 1.2 9.4 4.3 1.9 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Sec23_trunk PF04811.15 CAM37235.2 - 9.3e-40 136.7 0.0 3.2e-19 69.5 0.0 2.2 1 1 1 2 2 2 2 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CAM37235.2 - 6.7e-21 74.1 0.1 2.9e-19 68.8 0.0 2.9 3 0 0 3 3 3 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 CAM37235.2 - 4.9e-18 65.7 0.2 1.2e-17 64.4 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 CAM37235.2 - 4e-06 26.6 0.0 8.2e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.15 CAM37235.2 - 0.023 14.7 6.2 0.049 13.7 6.2 1.6 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger JAB PF01398.21 CAM37237.1 - 0.014 15.4 0.0 0.034 14.1 0.0 1.7 1 1 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease C1ORF64 PF15547.6 CAM37237.1 - 0.025 15.0 0.6 0.025 15.0 0.6 2.5 2 0 0 2 2 2 0 Steroid receptor-associated and regulated protein BT1 PF03092.16 CAM37239.1 - 1.4e-250 832.0 8.2 1.6e-250 831.8 8.2 1.0 1 0 0 1 1 1 1 BT1 family BT1 PF03092.16 CAM37240.1 - 3.1e-245 814.4 10.4 3.6e-245 814.2 10.4 1.0 1 0 0 1 1 1 1 BT1 family BT1 PF03092.16 CAM37241.1 - 6.4e-249 826.5 9.0 7.4e-249 826.3 9.0 1.0 1 0 0 1 1 1 1 BT1 family BT1 PF03092.16 CAM37242.1 - 1.6e-255 848.3 7.5 1.9e-255 848.1 7.5 1.0 1 0 0 1 1 1 1 BT1 family Ost5 PF05251.12 CAM37242.1 - 9.1 6.6 9.1 7.1 7.0 0.1 3.4 3 0 0 3 3 3 0 Oligosaccharyltransferase subunit 5 Dak1 PF02733.17 CAM37243.1 - 2.4e-91 305.9 1.5 3.5e-91 305.4 1.5 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 CAM37243.1 - 6.5e-38 130.4 2.6 6.5e-38 130.4 2.6 1.8 2 0 0 2 2 2 1 DAK2 domain zf-C3HC4_3 PF13920.6 CAM37245.1 - 1.5e-05 24.7 16.1 1.5e-05 24.7 16.1 2.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CAM37245.1 - 0.027 14.4 11.5 0.027 14.4 11.5 1.7 2 1 0 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 CAM37245.1 - 0.26 11.2 13.0 3 7.8 13.0 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 CAM37246.1 - 1.1e-06 28.4 16.0 6.7e-06 25.9 16.0 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CAM37246.1 - 0.039 13.9 12.6 0.14 12.1 12.6 2.0 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 CAM37246.1 - 6.8 6.7 17.9 93 3.0 16.3 3.0 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 4F5 PF04419.14 CAM37247.1 - 4.3e-08 33.9 6.1 4.3e-08 33.9 6.1 1.4 2 0 0 2 2 2 1 4F5 protein family zf-met2 PF12907.7 CAM37247.1 - 1.3e-05 25.2 0.2 1.3e-05 25.2 0.2 1.7 2 0 0 2 2 2 1 Zinc-binding zf-H2C2_2 PF13465.6 CAM37247.1 - 0.067 13.6 1.6 0.55 10.8 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 CAM37247.1 - 0.086 13.7 1.0 0.47 11.4 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Peptidase_M8 PF01457.16 CAM37248.1 - 3.7e-281 933.4 0.9 4.2e-281 933.2 0.9 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 CAM37249.1 - 1.5e-283 941.3 0.1 1.7e-283 941.1 0.1 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 CAM37250.1 - 2e-58 198.4 0.6 4.1e-58 197.4 0.6 1.4 1 1 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 CAM37251.1 - 7.6e-192 638.7 6.0 8.5e-192 638.5 6.0 1.0 1 0 0 1 1 1 1 Leishmanolysin Macin PF14865.6 CAM37251.1 - 0.043 14.4 0.5 0.72 10.4 0.0 2.7 2 0 0 2 2 2 0 Macin Peptidase_M8 PF01457.16 CAM37252.1 - 6.6e-273 906.2 1.5 7.6e-273 906.0 1.5 1.0 1 0 0 1 1 1 1 Leishmanolysin FA_desaturase PF00487.24 CAM37252.1 - 1.1 9.0 3.6 14 5.4 0.2 3.0 4 0 0 4 4 4 0 Fatty acid desaturase Peptidase_M8 PF01457.16 CAM37253.1 - 5.6e-270 896.5 0.5 6.4e-270 896.3 0.5 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 CAM37254.2 - 2.9e-218 725.8 3.0 3.6e-218 725.5 3.0 1.0 1 0 0 1 1 1 1 Leishmanolysin Macin PF14865.6 CAM37254.2 - 0.038 14.5 0.9 1.9 9.1 0.1 3.2 3 0 0 3 3 3 0 Macin CbtB PF09489.10 CAM37254.2 - 0.97 9.6 3.9 0.95 9.6 0.5 2.2 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) Peptidase_M8 PF01457.16 CAM37255.1 - 1.3e-279 928.3 2.4 1.5e-279 928.1 2.4 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 CAM37256.1 - 1.4e-282 938.1 2.0 1.6e-282 937.9 2.0 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 CAM37257.1 - 1.4e-277 921.6 2.3 1.6e-277 921.4 2.3 1.0 1 0 0 1 1 1 1 Leishmanolysin Macin PF14865.6 CAM37257.1 - 0.1 13.1 0.6 1.1 9.8 0.1 2.7 2 0 0 2 2 2 0 Macin Peptidase_M8 PF01457.16 CAM37258.1 - 2.8e-232 772.1 0.4 3.1e-232 771.9 0.4 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 CAM37259.1 - 3.6e-278 923.6 3.8 4.1e-278 923.4 3.8 1.0 1 0 0 1 1 1 1 Leishmanolysin Macin PF14865.6 CAM37259.1 - 0.15 12.6 1.2 2.9 8.5 0.1 2.9 2 0 0 2 2 2 0 Macin Peptidase_M8 PF01457.16 CAM37260.1 - 1.1e-248 826.3 4.1 1.5e-248 825.8 4.1 1.2 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 CAM37261.1 - 1.1e-258 859.2 1.3 1.6e-258 858.7 1.3 1.2 1 0 0 1 1 1 1 Leishmanolysin CbtB PF09489.10 CAM37261.1 - 3.6 7.8 10.1 1.2 9.3 0.5 3.1 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) Peptidase_M8 PF01457.16 CAM37262.1 - 1.8e-278 924.5 3.1 2.1e-278 924.3 3.1 1.0 1 0 0 1 1 1 1 Leishmanolysin Macin PF14865.6 CAM37262.1 - 0.16 12.5 1.0 3.4 8.3 0.1 2.8 2 0 0 2 2 2 0 Macin DUF3040 PF11239.8 CAM37262.1 - 0.72 10.2 5.2 11 6.4 1.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Pkinase PF00069.25 CAM37263.1 - 1.6e-63 214.5 0.0 1.9e-63 214.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM37263.1 - 8.9e-28 97.3 0.0 9.2e-27 93.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CAM37263.1 - 0.00092 18.6 0.1 0.0015 18.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CAM37263.1 - 0.0028 17.0 0.0 0.0042 16.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Thionin PF00321.17 CAM37264.2 - 9 6.9 7.7 44 4.7 0.2 3.7 3 0 0 3 3 3 0 Plant thionin NAD_Gly3P_dh_C PF07479.14 CAM37265.1 - 7.1e-47 159.3 1.5 5.4e-46 156.4 0.2 2.1 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 CAM37265.1 - 6.9e-44 149.6 0.0 1e-43 149.0 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.14 CAM37265.1 - 2.2e-05 24.1 0.0 4.4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 CAM37265.1 - 0.0063 17.1 0.0 0.016 15.8 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF1188 PF06690.11 CAM37265.1 - 0.013 15.1 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) NAD_binding_2 PF03446.15 CAM37265.1 - 0.018 15.2 0.1 0.069 13.3 0.0 2.0 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 CAM37265.1 - 0.032 14.1 0.2 0.068 13.0 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HEAT_EZ PF13513.6 CAM37266.1 - 0.035 14.6 1.0 1.1 9.8 0.2 3.3 2 0 0 2 2 2 0 HEAT-like repeat GTP_EFTU PF00009.27 CAM37267.2 - 0.0022 17.6 0.0 0.014 14.9 0.0 2.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF1281 PF06924.11 CAM37267.2 - 0.0041 16.7 0.1 0.18 11.3 0.1 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1281) Pox_A_type_inc PF04508.12 CAM37267.2 - 0.023 14.5 2.5 0.16 11.9 0.9 3.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Bap31_Bap29_C PF18035.1 CAM37267.2 - 0.079 13.0 0.1 0.079 13.0 0.1 4.6 5 0 0 5 5 5 0 Bap31/Bap29 cytoplasmic coiled-coil domain HU-CCDC81_bac_2 PF18175.1 CAM37267.2 - 0.47 10.4 3.5 1.5 8.7 0.1 3.5 3 1 1 4 4 4 0 CCDC81-like prokaryotic HU domain 2 ADH_zinc_N PF00107.26 CAM37270.2 - 3.7e-15 56.1 0.0 6.7e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CAM37270.2 - 4.6e-08 34.2 0.0 7.2e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CAM37270.2 - 5.3e-08 32.7 0.1 2.9e-07 30.3 0.1 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CAM37271.1 - 6.9e-16 58.4 1.1 1.1e-15 57.8 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CAM37271.1 - 7e-15 56.3 0.0 1.4e-14 55.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CAM37271.1 - 7.9e-05 22.5 0.0 0.00058 19.7 0.0 2.4 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CAF1A PF12253.8 CAM37272.1 - 2.1e-09 37.4 0.5 2.1e-09 37.4 0.5 3.9 3 1 1 4 4 4 1 Chromatin assembly factor 1 subunit A SDA1 PF05285.12 CAM37272.1 - 1.5 8.2 34.7 0.26 10.7 2.1 3.1 3 0 0 3 3 3 0 SDA1 Borrelia_P83 PF05262.11 CAM37272.1 - 4.8 5.6 22.6 0.053 12.0 13.6 1.9 2 0 0 2 2 2 0 Borrelia P83/100 protein Adenine_deam_C PF13382.6 CAM37273.1 - 0.13 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Adenine deaminase C-terminal domain ABC1 PF03109.16 CAM37275.1 - 5.4e-23 81.4 0.0 1.1e-22 80.4 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Endonuclease_NS PF01223.23 CAM37276.1 - 6e-50 170.2 0.0 1.2e-49 169.2 0.0 1.4 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.6 CAM37276.1 - 0.063 13.4 0.1 0.17 12.0 0.1 1.6 1 1 0 1 1 1 0 DNA/RNA non-specific endonuclease B277 PF17623.2 CAM37276.1 - 3 6.8 4.6 0.37 9.8 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function Rax2 PF12768.7 CAM37277.1 - 0.0071 15.8 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Cortical protein marker for cell polarity zf-CCCH PF00642.24 CAM37279.1 - 0.00025 20.9 3.1 0.00044 20.1 3.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CAM37279.1 - 0.025 14.6 3.1 0.045 13.8 3.1 1.4 1 0 0 1 1 1 0 Zinc finger domain DUF1751 PF08551.10 CAM37282.2 - 0.0012 19.4 1.7 0.007 16.9 0.4 2.3 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) HEAT PF02985.22 CAM37283.2 - 1.2e-08 34.5 29.6 0.014 15.6 0.1 8.9 7 0 0 7 7 7 4 HEAT repeat HEAT_2 PF13646.6 CAM37283.2 - 0.0015 18.9 32.3 0.33 11.3 0.0 9.4 10 0 0 10 10 10 2 HEAT repeats HEAT_EZ PF13513.6 CAM37283.2 - 0.046 14.2 21.6 3.3 8.3 0.2 7.8 7 0 0 7 7 7 0 HEAT-like repeat Vac14_Fab1_bd PF12755.7 CAM37283.2 - 0.072 13.7 0.0 1 10.0 0.0 2.9 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region RRM_1 PF00076.22 CAM37284.2 - 4.1e-42 141.8 0.5 6.3e-16 58.0 0.0 6.3 5 1 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CAM37284.2 - 3.1e-05 23.5 0.0 0.052 13.1 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CAM37284.2 - 0.00031 20.5 0.0 0.12 12.3 0.0 3.6 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 CAM37284.2 - 0.0075 16.1 2.2 3.6 7.4 0.0 3.8 5 0 0 5 5 5 2 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 CAM37284.2 - 0.013 15.6 0.0 0.22 11.7 0.0 3.0 4 0 0 4 4 4 0 RNA recognition motif Nup35_RRM_2 PF14605.6 CAM37284.2 - 0.14 12.2 0.0 1.2 9.1 0.0 2.5 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif XS PF03468.14 CAM37284.2 - 0.18 12.1 0.4 7.1 7.0 0.0 2.9 2 0 0 2 2 2 0 XS domain Aa_trans PF01490.18 CAM37285.1 - 1e-38 133.2 33.8 1.3e-38 132.8 33.8 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein dCMP_cyt_deam_1 PF00383.23 CAM37286.1 - 2e-12 46.9 3.7 6.6e-10 38.8 3.7 3.0 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CAM37286.1 - 1.8e-11 44.0 1.4 2.6e-05 24.0 0.0 3.2 2 1 0 2 2 2 2 MafB19-like deaminase Bd3614-deam PF14439.6 CAM37286.1 - 0.54 10.3 3.1 0.37 10.8 0.4 1.9 1 1 1 2 2 2 0 Bd3614-like deaminase MTHFR PF02219.17 CAM37287.2 - 0.011 15.0 0.0 1.9 7.7 0.0 2.7 3 0 0 3 3 3 0 Methylenetetrahydrofolate reductase Toxin_4 PF00706.17 CAM37288.2 - 0.1 13.0 1.4 0.3 11.5 0.3 2.4 2 0 0 2 2 2 0 Anenome neurotoxin WD40 PF00400.32 CAM37289.1 - 4e-65 214.2 18.3 1.3e-08 35.3 0.1 8.1 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM37289.1 - 2.8e-23 82.0 2.8 0.00026 21.2 0.1 7.4 1 1 7 8 8 8 7 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CAM37289.1 - 6.6e-13 48.6 1.7 0.037 13.4 0.1 6.5 4 2 3 7 7 7 3 WD40-like domain eIF2A PF08662.11 CAM37289.1 - 6.9e-10 39.1 3.2 0.00019 21.4 0.1 3.3 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CAM37289.1 - 8.2e-10 37.9 11.7 0.085 11.5 0.1 5.7 2 1 4 6 6 6 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CAM37289.1 - 0.0047 15.9 8.3 5.9 5.7 0.2 4.9 1 1 5 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF5570 PF17731.1 CAM37289.1 - 0.011 15.8 12.6 5.6 7.1 0.1 5.2 1 1 3 5 5 5 0 Family of unknown function (DUF5570) DUF4934 PF16288.5 CAM37289.1 - 0.061 13.3 1.0 7.4 6.5 0.0 3.7 4 1 0 4 4 4 0 Domain of unknown function (DUF4934) Invasin_D3 PF09134.10 CAM37289.1 - 0.17 12.2 1.2 1.2 9.5 0.2 2.7 2 1 1 3 3 3 0 Invasin, domain 3 DFRP_C PF16543.5 CAM37290.1 - 2.8e-12 47.0 7.5 2.8e-12 47.0 7.5 2.7 2 1 0 2 2 2 1 DRG Family Regulatory Proteins, Tma46 BetaGal_dom3 PF13363.6 CAM37292.1 - 0.048 13.2 0.1 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 Beta-galactosidase, domain 3 TPR_2 PF07719.17 CAM37293.1 - 5.4e-05 23.0 1.6 0.22 11.7 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CAM37293.1 - 0.00028 21.1 5.1 0.001 19.3 5.1 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 CAM37293.1 - 0.0021 17.8 0.5 0.11 12.4 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF2153 PF09921.9 CAM37293.1 - 0.031 14.1 0.1 0.065 13.1 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) TPR_8 PF13181.6 CAM37293.1 - 0.07 13.4 1.0 20 5.7 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 CAM37293.1 - 0.077 12.9 9.8 0.32 10.9 3.1 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 CAM37293.1 - 0.15 12.2 4.3 4.8 7.4 0.0 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.25 CAM37294.1 - 1.5e-22 80.2 0.0 1e-17 64.4 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM37294.1 - 3.1e-05 23.4 0.0 0.0093 15.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase A_deaminase PF00962.22 CAM37295.1 - 1.8e-10 40.7 1.4 4.2e-05 23.0 0.1 3.2 3 0 0 3 3 3 3 Adenosine/AMP deaminase NTF2 PF02136.20 CAM37296.1 - 6.6e-26 91.2 0.3 7.2e-26 91.1 0.3 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 CAM37296.1 - 0.00023 21.6 0.0 0.00027 21.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Lumazine_bd_2 PF12893.7 CAM37296.1 - 0.027 15.2 0.1 0.046 14.4 0.1 1.4 1 0 0 1 1 1 0 Putative lumazine-binding Nop16 PF09420.10 CAM37297.1 - 3.4e-14 53.4 2.2 3.4e-11 43.6 0.8 2.1 1 1 1 2 2 2 2 Ribosome biogenesis protein Nop16 YpjP PF14005.6 CAM37297.1 - 0.069 13.2 0.1 0.1 12.7 0.1 1.2 1 0 0 1 1 1 0 YpjP-like protein Histone PF00125.24 CAM37298.1 - 6.1e-43 146.3 5.0 6.8e-43 146.2 5.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CAM37298.1 - 5.8e-06 26.5 0.2 9.5e-06 25.8 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 CAM37298.1 - 2.1e-05 24.8 0.0 4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CAM37298.1 - 2.2e-05 24.5 0.1 4e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 CAM37298.1 - 0.01 15.9 0.1 0.015 15.3 0.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CAM37298.1 - 0.055 13.5 0.0 0.089 12.8 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Jak1_Phl PF17887.1 CAM37299.1 - 0.091 12.7 0.2 0.28 11.1 0.1 1.9 1 1 0 1 1 1 0 Jak1 pleckstrin homology-like domain FKBP_C PF00254.28 CAM37300.1 - 2.6e-26 91.7 0.0 3.6e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF2895 PF11444.8 CAM37300.1 - 0.18 11.2 0.0 0.24 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2895) IQ PF00612.27 CAM37301.2 - 8.5e-06 25.1 50.5 0.12 12.2 0.9 9.3 8 0 0 8 8 8 7 IQ calmodulin-binding motif Ras PF00071.22 CAM37302.1 - 3.6e-58 195.8 0.1 4.1e-58 195.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAM37302.1 - 2e-32 111.9 0.0 3.6e-32 111.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAM37302.1 - 4.1e-14 52.4 0.0 5.1e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CAM37302.1 - 1.5e-05 24.7 0.1 3.4e-05 23.5 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CAM37302.1 - 1.5e-05 25.0 0.2 3.5e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ploopntkinase3 PF18751.1 CAM37302.1 - 0.00043 20.2 0.0 0.95 9.3 0.0 2.2 2 0 0 2 2 2 2 P-loop Nucleotide Kinase3 RsgA_GTPase PF03193.16 CAM37302.1 - 0.00054 19.9 0.4 0.053 13.4 0.1 2.4 1 1 0 2 2 2 1 RsgA GTPase DLIC PF05783.11 CAM37302.1 - 0.0013 17.6 0.0 1.1 8.0 0.0 2.1 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) SRPRB PF09439.10 CAM37302.1 - 0.0059 16.1 0.2 0.01 15.2 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 CAM37302.1 - 0.0078 16.5 0.0 0.015 15.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 CAM37302.1 - 0.016 15.0 0.1 0.082 12.7 0.0 1.9 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 CAM37302.1 - 0.017 14.8 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CAM37302.1 - 0.02 14.4 0.1 0.031 13.8 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Amidase02_C PF12123.8 CAM37302.1 - 0.032 13.9 0.1 0.27 10.9 0.0 2.3 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase FeoB_N PF02421.18 CAM37302.1 - 0.034 13.7 0.0 0.067 12.7 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B Gtr1_RagA PF04670.12 CAM37302.1 - 0.04 13.3 0.1 0.048 13.0 0.1 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Septin PF00735.18 CAM37302.1 - 0.056 12.7 0.1 0.092 12.0 0.1 1.3 1 0 0 1 1 1 0 Septin ABC_tran PF00005.27 CAM37302.1 - 0.082 13.4 0.0 0.1 13.1 0.0 1.4 1 1 0 1 1 1 0 ABC transporter DUF2101 PF09874.9 CAM37303.1 - 9.5 5.9 12.3 1.2 8.8 8.2 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) DUF4064 PF13273.6 CAM37304.2 - 0.3 11.4 0.0 0.3 11.4 0.0 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF4064) CALM_bind PF16025.5 CAM37305.1 - 0.15 12.6 1.2 0.4 11.2 1.2 1.8 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding HscB_4_cys PF18256.1 CAM37306.2 - 0.24 11.2 2.1 0.44 10.4 0.1 2.6 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif CAMSAP_CC1 PF17095.5 CAM37306.2 - 5.9 6.8 10.4 0.036 13.9 1.3 2.1 2 0 0 2 2 2 0 Spectrin-binding region of Ca2+-Calmodulin Plk4_PB2 PF18409.1 CAM37307.1 - 0.0076 16.9 6.6 0.43 11.3 1.5 3.2 2 1 0 2 2 2 2 Polo-like Kinase 4 Polo Box 2 TetR_C_24 PF17932.1 CAM37307.1 - 0.053 13.8 0.7 0.053 13.8 0.7 2.9 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Dishevelled PF02377.15 CAM37307.1 - 0.82 10.1 7.0 0.22 12.0 0.2 3.4 3 0 0 3 3 3 0 Dishevelled specific domain Histone PF00125.24 CAM37308.1 - 6.1e-43 146.3 5.0 6.8e-43 146.2 5.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CAM37308.1 - 5.8e-06 26.5 0.2 9.5e-06 25.8 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 CAM37308.1 - 2.1e-05 24.8 0.0 4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CAM37308.1 - 2.2e-05 24.5 0.1 4e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 CAM37308.1 - 0.01 15.9 0.1 0.015 15.3 0.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CAM37308.1 - 0.055 13.5 0.0 0.089 12.8 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.24 CAM37309.1 - 6.1e-43 146.3 5.0 6.8e-43 146.2 5.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CAM37309.1 - 5.8e-06 26.5 0.2 9.5e-06 25.8 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 CAM37309.1 - 2.1e-05 24.8 0.0 4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CAM37309.1 - 2.2e-05 24.5 0.1 4e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 CAM37309.1 - 0.01 15.9 0.1 0.015 15.3 0.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CAM37309.1 - 0.055 13.5 0.0 0.089 12.8 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.24 CAM37310.1 - 6.1e-43 146.3 5.0 6.8e-43 146.2 5.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CAM37310.1 - 5.8e-06 26.5 0.2 9.5e-06 25.8 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 CAM37310.1 - 2.1e-05 24.8 0.0 4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CAM37310.1 - 2.2e-05 24.5 0.1 4e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 CAM37310.1 - 0.01 15.9 0.1 0.015 15.3 0.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CAM37310.1 - 0.055 13.5 0.0 0.089 12.8 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated P34-Arc PF04045.14 CAM37311.1 - 0.00023 20.9 0.0 0.00038 20.3 0.0 1.2 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc DUF1382 PF07131.11 CAM37311.1 - 0.0076 16.2 0.2 0.05 13.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1382) PNP_UDP_1 PF01048.20 CAM37312.1 - 2.1e-45 154.8 0.6 2.6e-45 154.5 0.6 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily PreAtp-grasp PF18604.1 CAM37312.1 - 0.16 11.7 0.0 0.51 10.0 0.0 1.8 2 0 0 2 2 2 0 Pre ATP-grasp domain Mito_carr PF00153.27 CAM37313.1 - 1.9e-21 75.8 5.5 3.7e-08 33.2 0.6 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.22 CAM37314.2 - 1.1e-06 28.4 0.0 2.3e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AP3D1 PF06375.11 CAM37314.2 - 0.51 10.6 5.7 1.1 9.5 5.7 1.6 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 CH_2 PF06294.11 CAM37315.2 - 9.3e-24 83.4 0.0 1.9e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 CAM37315.2 - 0.03 14.1 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain DnaJ PF00226.31 CAM37316.2 - 2e-06 27.8 0.5 3.8e-06 26.9 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain Autoind_synth PF00765.17 CAM37317.1 - 0.02 14.4 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 Autoinducer synthase YABBY PF04690.13 CAM37317.1 - 0.15 12.7 0.0 0.23 12.0 0.0 1.3 1 0 0 1 1 1 0 YABBY protein EMP24_GP25L PF01105.24 CAM37318.1 - 0.67 9.9 6.5 2.4 8.0 0.0 3.3 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD MIF4G PF02854.19 CAM37319.1 - 8.1e-14 51.8 3.8 1.1e-13 51.3 0.6 2.5 3 0 0 3 3 3 1 MIF4G domain Herpes_BLRF2 PF05812.12 CAM37319.1 - 0.017 15.2 0.9 0.045 13.9 0.9 1.6 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein DUF4041 PF13250.6 CAM37319.1 - 0.11 12.3 0.1 0.5 10.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) Sporozoite_P67 PF05642.11 CAM37319.1 - 0.89 7.6 3.2 1.4 6.9 3.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF1104 PF06518.11 CAM37319.1 - 3.9 7.9 6.2 41 4.6 0.1 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1104) LsmAD PF06741.13 CAM37323.1 - 1.5e-18 67.1 2.0 4.7e-18 65.5 2.0 1.9 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.6 CAM37323.1 - 4.3e-11 42.8 0.0 7.7e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain TPR_2 PF07719.17 CAM37325.2 - 0.022 14.8 0.6 4.1 7.7 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3730 PF12530.8 CAM37325.2 - 0.027 14.0 2.8 0.036 13.6 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3730) zf-C3HC4_3 PF13920.6 CAM37326.1 - 1.4e-15 56.8 11.3 3e-15 55.8 11.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CAM37326.1 - 4.9e-09 35.9 11.2 8.6e-09 35.1 11.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CAM37326.1 - 4.5e-06 26.9 13.1 9.9e-06 25.8 13.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CAM37326.1 - 0.0072 16.1 14.4 0.016 15.0 14.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CAM37326.1 - 0.093 12.7 12.1 0.24 11.4 12.1 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.6 CAM37326.1 - 0.14 12.0 8.1 0.26 11.1 8.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TPH PF13868.6 CAM37327.1 - 5.3e-65 219.2 158.5 5.3e-65 219.2 158.5 2.0 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain Ras PF00071.22 CAM37328.1 - 1.8e-53 180.4 0.0 2.2e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAM37328.1 - 7.5e-30 103.6 0.0 1.5e-29 102.7 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAM37328.1 - 1.4e-11 44.2 0.0 1.8e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CAM37328.1 - 3.3e-06 26.8 0.0 0.00044 19.9 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CAM37328.1 - 1.5e-05 25.0 0.0 2.1e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CAM37328.1 - 0.00014 21.3 0.2 0.0002 20.8 0.2 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CAM37328.1 - 0.00061 19.7 0.0 0.03 14.3 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 CAM37328.1 - 0.0015 19.1 0.0 0.0057 17.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 CAM37328.1 - 0.0028 17.4 0.0 0.016 14.9 0.0 2.0 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 CAM37328.1 - 0.003 18.0 0.1 0.0071 16.8 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 CAM37328.1 - 0.016 14.6 0.0 0.024 14.1 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_33 PF13671.6 CAM37328.1 - 0.019 15.1 0.0 0.036 14.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 CAM37328.1 - 0.027 14.3 0.3 1.9 8.2 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 CAM37328.1 - 0.028 14.9 0.0 0.065 13.7 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 CAM37328.1 - 0.052 13.8 0.2 0.39 11.0 0.0 2.3 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.22 CAM37328.1 - 0.053 13.9 0.0 0.17 12.3 0.0 1.8 2 0 0 2 2 2 0 RNA helicase Septin PF00735.18 CAM37328.1 - 0.095 12.0 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Septin IIGP PF05049.13 CAM37328.1 - 0.1 11.6 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) DUF87 PF01935.17 CAM37328.1 - 0.19 11.8 0.5 4.5 7.3 0.1 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain Ras PF00071.22 CAM37329.1 - 3.8e-46 156.7 0.0 4.4e-46 156.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAM37329.1 - 3.3e-26 91.9 0.0 5e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAM37329.1 - 6.3e-07 29.0 0.0 7.1e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CAM37329.1 - 6.5e-05 22.6 0.0 0.0018 17.8 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CAM37329.1 - 7.2e-05 22.2 0.0 8.4e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CAM37329.1 - 0.027 14.5 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gemini_mov PF01708.16 CAM37330.1 - 0.4 10.5 2.2 18 5.2 0.0 2.2 2 0 0 2 2 2 0 Geminivirus putative movement protein RIB43A PF05914.12 CAM37331.1 - 9e-74 248.5 63.5 1.1e-73 248.2 63.5 1.0 1 0 0 1 1 1 1 RIB43A zf-RanBP PF00641.18 CAM37332.1 - 3.1e-07 29.6 23.3 0.0011 18.3 1.9 3.4 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others DZR PF12773.7 CAM37332.1 - 3.1e-06 27.1 14.5 0.001 19.1 8.1 2.4 1 1 1 2 2 2 2 Double zinc ribbon Ima1_N PF09779.9 CAM37332.1 - 0.069 14.0 10.3 0.44 11.4 1.7 3.3 3 0 0 3 3 3 0 Ima1 N-terminal domain zinc-ribbon_6 PF10005.9 CAM37332.1 - 0.49 11.1 10.8 0.77 10.5 0.2 3.2 3 0 0 3 3 3 0 zinc-ribbon domain CSN7a_helixI PF18392.1 CAM37334.1 - 1.2 9.1 5.1 4.1 7.4 0.7 3.4 2 0 0 2 2 2 0 COP9 signalosome complex subunit 7a helix I domain Atx10homo_assoc PF09759.9 CAM37335.1 - 3.4e-23 81.5 0.0 5.6e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Methyltransf_23 PF13489.6 CAM37338.1 - 1.5e-19 70.4 0.0 2.1e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAM37338.1 - 1.5e-06 28.8 0.1 6.8e-05 23.4 0.0 2.3 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAM37338.1 - 4e-06 27.5 0.0 5.3e-05 23.9 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAM37338.1 - 0.004 17.0 0.0 0.011 15.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAM37338.1 - 0.035 14.8 0.0 2.6 8.8 0.0 2.6 1 1 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 CAM37338.1 - 0.039 13.3 0.0 0.068 12.5 0.0 1.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Yos9_DD PF17880.1 CAM37338.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Yos9 dimerzation domain DUF1861 PF08950.10 CAM37339.1 - 1.8e-116 388.6 0.1 2.1e-116 388.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) DUF1861 PF08950.10 CAM37340.1 - 1.9e-115 385.2 0.0 2.1e-115 385.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) DUF1861 PF08950.10 CAM37341.1 - 1.1e-120 402.3 0.1 1.3e-120 402.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) DUF1861 PF08950.10 CAM37342.1 - 2.5e-121 404.5 0.0 2.9e-121 404.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) DUF1861 PF08950.10 CAM37343.1 - 2.3e-114 381.6 0.0 2.6e-114 381.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) DUF5565 PF17720.1 CAM37343.1 - 0.067 12.0 0.0 0.096 11.5 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5565) DUF1861 PF08950.10 CAM37344.1 - 9.6e-120 399.3 0.0 1.1e-119 399.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) DUF1861 PF08950.10 CAM37345.1 - 6.5e-120 399.9 0.0 7.4e-120 399.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) PHO4 PF01384.20 CAM37346.1 - 3.9e-111 371.3 17.5 4.6e-111 371.1 17.5 1.1 1 0 0 1 1 1 1 Phosphate transporter family BT1 PF03092.16 CAM37347.1 - 3.7e-191 635.9 14.5 4.4e-191 635.7 14.5 1.0 1 0 0 1 1 1 1 BT1 family FA_desaturase PF00487.24 CAM37348.1 - 1.5e-26 93.7 26.0 1.5e-26 93.7 26.0 1.7 1 1 1 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.8 CAM37348.1 - 0.049 13.8 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) SET PF00856.28 CAM37349.1 - 1.3e-09 38.6 0.0 4.6e-08 33.6 0.0 3.0 1 1 0 1 1 1 1 SET domain LPD22 PF18834.1 CAM37349.1 - 0.12 12.7 0.8 0.24 11.6 0.8 1.5 1 0 0 1 1 1 0 Large polyvalent protein associated domain 22 CotJB PF12652.7 CAM37350.1 - 0.023 14.9 5.3 0.45 10.8 3.4 3.1 2 1 1 3 3 3 0 CotJB protein Terminase_4 PF05119.12 CAM37350.1 - 0.14 12.6 0.5 0.49 10.8 0.2 2.1 2 0 0 2 2 2 0 Phage terminase, small subunit DNA_pol_alpha_N PF12254.8 CAM37351.1 - 0.11 12.6 0.1 0.31 11.2 0.1 1.8 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal Amastin PF07344.11 CAM37353.1 - 1.9e-54 183.7 11.1 2.3e-54 183.5 11.1 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein TnsD PF15978.5 CAM37354.1 - 0.044 12.8 1.3 0.24 10.3 0.1 1.9 1 1 1 2 2 2 0 Tn7-like transposition protein D Peptidase_M8 PF01457.16 CAM37355.1 - 5.8e-94 315.7 7.9 6.6e-94 315.5 7.9 1.0 1 0 0 1 1 1 1 Leishmanolysin Macin PF14865.6 CAM37355.1 - 6.6 7.4 9.5 1.8 9.2 0.7 3.0 3 1 0 3 3 3 0 Macin Peptidase_M8 PF01457.16 CAM37356.1 - 4.7e-173 576.7 0.0 5.9e-173 576.3 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 CAM37357.1 - 3.5e-148 494.6 0.0 4e-148 494.4 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 CAM37358.1 - 2e-289 960.7 1.1 2.3e-289 960.5 1.1 1.0 1 0 0 1 1 1 1 Leishmanolysin Macin PF14865.6 CAM37358.1 - 0.0037 17.8 0.8 0.015 15.8 0.1 2.4 2 0 0 2 2 2 1 Macin Peptidase_M8 PF01457.16 CAM37360.1 - 3.1e-287 953.5 0.5 3.5e-287 953.3 0.5 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 CAM37362.1 - 5.3e-280 929.6 0.3 6e-280 929.4 0.3 1.0 1 0 0 1 1 1 1 Leishmanolysin Reprolysin_3 PF13582.6 CAM37362.1 - 0.078 13.5 0.0 0.87 10.1 0.0 2.3 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M8 PF01457.16 CAM37363.1 - 2.9e-288 956.9 2.7 3.3e-288 956.7 2.7 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 CAM37364.1 - 1.2e-287 954.9 2.0 1.3e-287 954.7 2.0 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 CAM37365.2 - 3.8e-287 953.2 1.0 4.3e-287 953.0 1.0 1.0 1 0 0 1 1 1 1 Leishmanolysin Macin PF14865.6 CAM37365.2 - 0.027 15.0 1.2 0.073 13.6 0.2 2.3 2 0 0 2 2 2 0 Macin Peptidase_M8 PF01457.16 CAM37366.1 - 7.5e-285 945.6 3.9 8.5e-285 945.4 3.9 1.0 1 0 0 1 1 1 1 Leishmanolysin Macin PF14865.6 CAM37366.1 - 0.01 16.3 1.0 0.04 14.5 0.1 2.5 2 0 0 2 2 2 0 Macin Peptidase_M8 PF01457.16 CAM37367.1 - 3.2e-286 950.1 2.3 3.6e-286 949.9 2.3 1.0 1 0 0 1 1 1 1 Leishmanolysin Macin PF14865.6 CAM37367.1 - 0.011 16.3 1.0 0.04 14.5 0.1 2.5 2 0 0 2 2 2 0 Macin Peptidase_M8 PF01457.16 CAM37368.1 - 1.5e-270 898.4 0.5 1.7e-270 898.2 0.5 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 CAM37369.1 - 8.2e-204 678.2 4.9 9.3e-204 678.0 4.9 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 CAM37370.1 - 7.9e-235 780.5 2.0 9.8e-235 780.2 2.0 1.0 1 0 0 1 1 1 1 Leishmanolysin Macin PF14865.6 CAM37370.1 - 0.14 12.7 1.3 3.2 8.4 0.1 2.7 2 0 0 2 2 2 0 Macin Peptidase_M8 PF01457.16 CAM37371.1 - 4.4e-58 197.3 0.4 8.8e-58 196.3 0.4 1.4 1 1 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 CAM37372.1 - 8.5e-158 526.3 0.4 9.4e-158 526.2 0.4 1.0 1 0 0 1 1 1 1 Leishmanolysin AIRC PF00731.20 CAM37374.1 - 0.11 12.0 1.5 0.22 11.1 0.4 2.0 2 0 0 2 2 2 0 AIR carboxylase ESCRT-II PF05871.12 CAM37374.1 - 0.24 11.6 3.8 0.74 10.1 3.8 1.9 1 1 0 1 1 1 0 ESCRT-II complex subunit IF-2B PF01008.17 CAM37375.1 - 9.3e-23 80.8 1.3 6.9e-18 64.8 0.6 3.0 2 2 0 2 2 2 2 Initiation factor 2 subunit family RMMBL PF07521.12 CAM37375.1 - 0.082 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain PITH PF06201.13 CAM37376.1 - 9e-21 74.7 0.0 1.1e-20 74.4 0.0 1.1 1 0 0 1 1 1 1 PITH domain Proteasome PF00227.26 CAM37377.1 - 2e-42 144.9 0.4 2.4e-42 144.6 0.4 1.1 1 0 0 1 1 1 1 Proteasome subunit DAP3 PF10236.9 CAM37378.1 - 3.4e-23 82.3 0.0 9.6e-20 71.0 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial ribosomal death-associated protein 3 T2SSE PF00437.20 CAM37378.1 - 0.0044 16.1 0.0 0.0064 15.6 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase_2 PF01637.18 CAM37378.1 - 0.063 13.2 0.0 0.16 11.9 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 CAM37378.1 - 0.079 13.3 0.0 0.16 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain RecA_dep_nuc PF16786.5 CAM37378.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Recombination enhancement, RecA-dependent nuclease AAA_29 PF13555.6 CAM37378.1 - 0.16 11.7 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Isochorismatase PF00857.20 CAM37381.1 - 4e-14 53.2 0.1 6.5e-14 52.5 0.1 1.3 1 1 0 1 1 1 1 Isochorismatase family Apyrase PF06079.11 CAM37384.1 - 0.012 14.8 0.0 0.044 13.0 0.0 1.7 2 0 0 2 2 2 0 Apyrase TPR_19 PF14559.6 CAM37385.1 - 0.035 14.6 2.1 1.3 9.6 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Plus-3 PF03126.18 CAM37386.1 - 1.8e-20 73.5 0.1 3.2e-20 72.7 0.1 1.4 1 0 0 1 1 1 1 Plus-3 domain zf-C3HC4_3 PF13920.6 CAM37386.1 - 4.4e-06 26.4 21.2 7e-06 25.8 21.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Vps39_2 PF10367.9 CAM37386.1 - 0.059 13.8 3.9 0.12 12.8 3.9 1.6 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 SF1-HH PF16275.5 CAM37386.1 - 0.43 10.9 2.5 0.24 11.7 0.5 1.6 2 0 0 2 2 2 0 Splicing factor 1 helix-hairpin domain CENP-Q PF13094.6 CAM37387.1 - 0.0043 17.3 11.8 0.0043 17.3 11.8 7.4 2 1 3 6 6 6 1 CENP-Q, a CENPA-CAD centromere complex subunit Ocular_alb PF02101.15 CAM37387.1 - 0.16 10.8 1.0 0.42 9.5 1.0 1.6 1 0 0 1 1 1 0 Ocular albinism type 1 protein TolA_bind_tri PF16331.5 CAM37388.2 - 0.0076 16.3 7.1 0.0076 16.3 7.1 8.3 7 3 3 10 10 10 3 TolA binding protein trimerisation RPW8 PF05659.11 CAM37388.2 - 0.037 13.7 0.1 0.037 13.7 0.1 3.8 2 1 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Sec8_exocyst PF04048.14 CAM37388.2 - 2.1 8.2 14.3 0.49 10.3 2.2 4.7 3 1 0 4 4 4 0 Sec8 exocyst complex component specific domain Pkinase PF00069.25 CAM37389.1 - 1.1e-39 136.4 0.0 1e-19 71.0 0.0 3.3 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM37389.1 - 3.6e-19 69.1 0.0 2.3e-11 43.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CAM37389.1 - 0.0066 16.4 0.9 0.53 10.2 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CAM37389.1 - 0.12 11.1 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase LRR_4 PF12799.7 CAM37391.1 - 1e-07 32.1 2.5 0.011 16.1 0.1 3.9 3 2 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM37391.1 - 1.7e-07 30.9 1.0 0.0019 17.9 0.0 3.5 2 1 1 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 CAM37391.1 - 0.092 12.2 0.0 3.9 6.9 0.0 2.2 2 0 0 2 2 2 0 Leucine-rich repeat UCH PF00443.29 CAM37394.2 - 1.8e-23 83.4 0.0 3.2e-22 79.3 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CAM37394.2 - 0.00045 19.9 0.0 5.9 6.4 0.0 3.8 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase AAA PF00004.29 CAM37396.1 - 6e-45 152.9 0.0 1.1e-44 152.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAM37396.1 - 2.2e-09 37.0 0.0 4.8e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 CAM37396.1 - 3.8e-09 36.4 0.1 1.4e-08 34.5 0.0 2.1 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 CAM37396.1 - 1.8e-08 34.4 0.1 5.7e-08 32.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CAM37396.1 - 1.2e-07 32.3 0.2 1.6e-05 25.4 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 CAM37396.1 - 1.2e-06 28.7 0.0 2.7e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CAM37396.1 - 5e-05 23.6 0.7 0.0066 16.7 0.7 2.6 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 CAM37396.1 - 7.5e-05 22.0 0.0 0.00013 21.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 CAM37396.1 - 0.00041 20.1 0.0 0.001 18.8 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 CAM37396.1 - 0.00042 19.9 0.1 0.0018 17.8 0.0 2.0 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_28 PF13521.6 CAM37396.1 - 0.00043 20.6 0.0 0.00076 19.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CAM37396.1 - 0.00063 20.3 0.0 0.0013 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CAM37396.1 - 0.0014 18.6 0.3 0.041 13.8 0.0 2.9 2 1 1 3 3 3 1 NACHT domain NTPase_1 PF03266.15 CAM37396.1 - 0.0015 18.4 0.2 0.0071 16.3 0.1 2.2 3 0 0 3 3 3 1 NTPase AAA_30 PF13604.6 CAM37396.1 - 0.002 17.9 0.1 0.0053 16.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 CAM37396.1 - 0.0027 17.5 0.1 0.01 15.7 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 CAM37396.1 - 0.0029 17.0 0.0 0.26 10.6 0.0 2.5 3 0 0 3 3 2 1 Bacterial TniB protein AAA_33 PF13671.6 CAM37396.1 - 0.0035 17.5 0.0 0.0066 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CAM37396.1 - 0.0037 17.3 0.0 0.0089 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CAM37396.1 - 0.0076 15.7 0.1 0.018 14.4 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 CAM37396.1 - 0.0095 15.9 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 CAM37396.1 - 0.012 14.8 0.0 0.035 13.3 0.0 1.6 1 1 0 2 2 2 0 TIP49 P-loop domain AAA_24 PF13479.6 CAM37396.1 - 0.019 14.7 0.2 0.043 13.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CAM37396.1 - 0.024 14.6 0.1 0.35 10.7 0.0 2.1 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 CAM37396.1 - 0.024 14.3 0.1 0.76 9.5 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.6 CAM37396.1 - 0.027 14.8 0.2 0.075 13.4 0.1 1.7 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 CAM37396.1 - 0.027 14.9 0.0 0.052 14.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 CAM37396.1 - 0.029 14.1 0.0 0.063 13.0 0.0 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 CAM37396.1 - 0.03 13.9 0.7 0.19 11.3 0.1 2.1 1 1 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 CAM37396.1 - 0.039 13.8 0.0 0.068 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein ABC_tran PF00005.27 CAM37396.1 - 0.048 14.2 0.0 0.16 12.5 0.0 2.1 1 1 0 1 1 1 0 ABC transporter cobW PF02492.19 CAM37396.1 - 0.072 12.7 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_11 PF13086.6 CAM37396.1 - 0.079 12.7 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 CAM37396.1 - 0.14 11.5 0.7 0.86 8.9 0.0 2.3 3 0 0 3 3 3 0 KaiC NB-ARC PF00931.22 CAM37396.1 - 0.16 11.1 0.0 1.2 8.2 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain HAGH_C PF16123.5 CAM37397.1 - 2.6e-07 31.0 0.1 7.2e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 CAM37397.1 - 2.6e-05 24.3 5.1 7e-05 22.9 5.1 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CAM37397.1 - 0.026 14.0 0.1 0.05 13.1 0.1 1.6 1 0 0 1 1 1 0 Beta-lactamase superfamily domain FAM199X PF15814.5 CAM37398.1 - 1.1 8.3 10.7 3.4 6.6 10.7 1.8 1 0 0 1 1 1 0 Protein family FAM199X SPX PF03105.19 CAM37398.1 - 6.8 6.5 7.5 20 5.0 7.5 1.8 1 0 0 1 1 1 0 SPX domain tRNA-synt_1e PF01406.19 CAM37400.1 - 5.6e-113 377.3 0.0 8.2e-113 376.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 CAM37400.1 - 0.0013 17.6 0.4 0.022 13.6 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 CAM37400.1 - 0.0097 14.2 0.0 0.24 9.6 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1c PF00749.21 CAM37400.1 - 0.0098 14.8 0.4 0.026 13.4 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain Peptidase_S78_2 PF14550.6 CAM37400.1 - 0.053 13.6 0.0 0.34 11.0 0.0 2.2 2 0 0 2 2 2 0 Putative phage serine protease XkdF Helicase_C PF00271.31 CAM37401.2 - 4e-05 23.9 0.0 0.00012 22.4 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HA2 PF04408.23 CAM37401.2 - 0.00011 22.5 0.0 0.00043 20.5 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) zf-C2H2_jaz PF12171.8 CAM37401.2 - 0.0092 16.2 2.0 0.018 15.3 2.0 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CAM37401.2 - 2.8 8.5 5.1 7.1 7.2 5.1 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type SET PF00856.28 CAM37402.1 - 7.4e-07 29.7 0.3 0.0086 16.5 0.0 3.3 2 1 0 2 2 2 2 SET domain DUF681 PF05080.12 CAM37402.1 - 0.065 13.9 0.2 0.24 12.1 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF681) Orn_Arg_deC_N PF02784.16 CAM37403.2 - 2.2e-80 269.6 0.0 3.2e-80 269.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 CAM37403.2 - 3.2e-13 49.7 0.0 1.1e-12 48.0 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.20 CAM37403.2 - 0.001 18.8 0.4 0.0043 16.7 0.0 2.0 2 0 0 2 2 2 1 Alanine racemase, N-terminal domain KxDL PF10241.9 CAM37404.1 - 0.011 16.0 1.8 0.011 16.0 1.8 7.7 5 2 2 7 7 7 0 Uncharacterized conserved protein SAC3_GANP PF03399.16 CAM37405.1 - 3.3e-13 49.7 1.2 6.2e-07 29.1 0.0 2.5 2 1 0 2 2 2 2 SAC3/GANP family SAC3_GANP PF03399.16 CAM37406.1 - 0.094 12.1 0.3 0.15 11.4 0.3 1.3 1 0 0 1 1 1 0 SAC3/GANP family Myotub-related PF06602.14 CAM37408.2 - 4.4e-57 193.6 0.0 4.1e-31 108.2 0.0 2.6 3 0 0 3 3 3 2 Myotubularin-like phosphatase domain GST_N PF02798.20 CAM37411.2 - 2.1e-09 37.6 0.0 3.7e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CAM37411.2 - 2.3e-09 37.5 0.0 7.3e-09 35.9 0.0 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CAM37411.2 - 7.5e-07 29.4 0.0 1.9e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CAM37411.2 - 0.0015 18.7 0.1 0.006 16.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CAM37411.2 - 0.016 15.4 0.0 0.03 14.5 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PUF PF00806.19 CAM37413.1 - 2.7e-33 111.8 5.4 0.00043 19.8 0.0 7.6 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat Phos_pyr_kin PF08543.12 CAM37413.1 - 0.053 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase Epimerase PF01370.21 CAM37414.1 - 0.00083 18.9 0.0 0.0018 17.8 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CAM37414.1 - 0.0038 17.1 2.4 0.0054 16.7 0.1 2.4 3 0 0 3 3 3 1 NAD(P)H-binding DapB_N PF01113.20 CAM37414.1 - 0.012 15.7 0.1 0.035 14.2 0.1 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 CAM37414.1 - 0.058 12.9 1.3 0.061 12.9 0.2 1.6 2 0 0 2 2 2 0 NmrA-like family DXP_reductoisom PF02670.16 CAM37414.1 - 0.1 13.3 0.6 0.3 11.8 0.1 2.0 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase S1-P1_nuclease PF02265.16 CAM37415.2 - 2.5e-60 204.4 0.0 3e-60 204.2 0.0 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease DUF866 PF05907.13 CAM37417.1 - 1.5e-32 112.7 0.0 1.8e-32 112.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Elf1 PF05129.13 CAM37417.1 - 0.039 14.0 0.0 0.074 13.1 0.0 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like DUF3222 PF11519.8 CAM37417.1 - 0.081 13.2 0.2 0.28 11.4 0.0 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3222) Bromodomain PF00439.25 CAM37418.2 - 0.075 13.1 0.0 19 5.4 0.0 2.3 2 0 0 2 2 2 0 Bromodomain IL2RB_N1 PF18707.1 CAM37420.1 - 0.17 12.4 0.0 0.34 11.5 0.0 1.4 1 0 0 1 1 1 0 Interleukin-2 receptor subunit beta N-terminal domain 1 ATP-synt_F PF01990.17 CAM37421.1 - 4.3e-34 116.7 0.0 5.1e-34 116.5 0.0 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit PGI PF00342.19 CAM37422.1 - 7.1e-257 852.7 3.1 8.1e-257 852.5 3.1 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF4473 PF14747.6 CAM37422.1 - 0.061 13.9 0.0 0.21 12.2 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) OsmC PF02566.19 CAM37423.1 - 0.0036 17.8 0.0 0.0074 16.7 0.0 1.5 1 1 0 1 1 1 1 OsmC-like protein Ald_Xan_dh_C2 PF02738.18 CAM37423.1 - 0.07 11.6 0.0 0.083 11.3 0.0 1.0 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase TPR_19 PF14559.6 CAM37425.2 - 0.0035 17.8 29.6 0.26 11.8 1.4 6.7 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 CAM37425.2 - 0.011 15.9 10.3 10 6.7 0.6 7.5 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_1 PF00515.28 CAM37425.2 - 0.021 14.7 8.2 0.78 9.7 1.1 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CAM37425.2 - 0.046 13.9 12.7 0.033 14.4 1.6 4.0 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 AWPM-19 PF05512.11 CAM37425.2 - 0.13 12.5 0.9 0.31 11.2 0.9 1.7 1 0 0 1 1 1 0 AWPM-19-like family TPR_2 PF07719.17 CAM37425.2 - 0.15 12.3 23.4 0.095 12.9 2.6 7.8 9 2 2 11 11 11 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CAM37425.2 - 0.52 10.4 4.9 0.47 10.6 0.6 3.1 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat DUF1771 PF08590.10 CAM37425.2 - 0.66 10.4 6.1 8.9 6.8 0.3 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) WW PF00397.26 CAM37426.1 - 4.1e-09 36.4 0.1 7.9e-09 35.4 0.1 1.5 1 0 0 1 1 1 1 WW domain FUSC_2 PF13515.6 CAM37431.1 - 1e-15 57.9 9.1 1e-15 57.9 9.1 2.5 2 0 0 2 2 2 2 Fusaric acid resistance protein-like NTPase_P4 PF11602.8 CAM37431.1 - 0.026 13.8 0.2 0.055 12.7 0.2 1.5 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 FSAP_sig_propep PF03032.15 CAM37431.1 - 0.031 14.3 0.4 0.15 12.1 0.4 2.2 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide FUSC_2 PF13515.6 CAM37432.2 - 8.3e-13 48.6 4.8 8.3e-13 48.6 4.8 2.5 2 0 0 2 2 2 1 Fusaric acid resistance protein-like DUF3021 PF11457.8 CAM37432.2 - 1.5 9.2 8.7 0.83 10.0 1.7 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3021) ALMT PF11744.8 CAM37432.2 - 3.1 6.5 6.9 0.22 10.3 0.6 2.0 2 0 0 2 2 2 0 Aluminium activated malate transporter Sulfatase PF00884.23 CAM37433.1 - 6.5e-05 22.5 0.0 0.0013 18.2 0.0 2.1 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 CAM37433.1 - 0.047 13.3 0.0 2 7.9 0.0 2.4 2 1 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase PsbW PF07123.12 CAM37433.1 - 0.17 11.9 2.4 4.8 7.2 0.0 2.9 3 0 0 3 3 3 0 Photosystem II reaction centre W protein (PsbW) TPR_1 PF00515.28 CAM37434.1 - 3.1e-17 61.6 12.6 6.7e-05 22.5 0.0 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 CAM37434.1 - 1.3e-16 59.3 21.2 0.0018 18.3 0.1 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 CAM37434.1 - 1.5e-16 59.2 0.4 2.6e-05 24.1 0.0 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 CAM37434.1 - 1.9e-11 43.4 16.8 1.6e-05 24.5 0.1 4.7 4 1 1 5 5 5 2 TPR repeat TPR_14 PF13428.6 CAM37434.1 - 4e-11 42.8 19.0 0.00011 22.8 0.2 7.2 6 3 3 9 9 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 CAM37434.1 - 1.4e-10 41.6 5.8 1e-06 29.3 0.6 6.6 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 CAM37434.1 - 3.1e-10 40.4 9.7 5.1e-05 23.7 0.1 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 CAM37434.1 - 3.1e-07 30.6 20.1 1.2 9.5 0.0 6.2 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_15 PF13429.6 CAM37434.1 - 1.3e-05 24.6 5.3 3.7e-05 23.1 5.3 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC8 PF04049.13 CAM37434.1 - 0.00037 20.6 0.0 0.0014 18.7 0.0 2.0 1 1 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_9 PF13371.6 CAM37434.1 - 0.00056 20.0 17.7 0.16 12.1 0.7 5.9 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 CAM37434.1 - 0.0015 18.8 1.9 1.8 9.1 0.2 4.5 4 0 0 4 4 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CAM37434.1 - 0.0025 18.0 16.9 0.018 15.3 0.6 5.4 5 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CAM37434.1 - 0.003 17.5 16.0 2.6 8.3 0.2 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat FAT PF02259.23 CAM37434.1 - 0.012 14.9 0.2 0.21 10.8 0.1 2.5 1 1 2 3 3 3 0 FAT domain PCP_red PF08369.10 CAM37434.1 - 0.031 14.5 0.0 0.085 13.1 0.0 1.8 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit TPR_10 PF13374.6 CAM37434.1 - 0.05 13.5 11.4 0.36 10.8 0.5 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CAM37434.1 - 0.085 13.5 6.5 2 9.2 0.0 4.8 6 0 0 6 6 4 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.21 CAM37436.2 - 7.6e-32 110.9 0.0 9.7e-32 110.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II PPL5 PF18168.1 CAM37437.1 - 3.9e-148 493.0 0.0 6e-148 492.3 0.0 1.3 1 0 0 1 1 1 1 Prim-pol family 5 PriCT_2 PF08707.11 CAM37437.1 - 8.3e-12 45.3 0.3 2.3e-11 43.9 0.3 1.8 1 0 0 1 1 1 1 Primase C terminal 2 (PriCT-2) PBP1_TM PF14812.6 CAM37437.1 - 0.56 10.6 2.2 1.1 9.7 2.2 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Metallophos PF00149.28 CAM37439.1 - 4.9e-28 99.0 0.0 8.9e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-TRAF PF02176.18 CAM37439.1 - 0.00029 21.5 3.0 0.00029 21.5 3.0 3.3 1 1 2 3 3 3 1 TRAF-type zinc finger EF-hand_1 PF00036.32 CAM37439.1 - 0.0027 17.1 0.1 0.1 12.2 0.1 3.0 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 CAM37439.1 - 0.0083 16.6 0.2 0.21 12.0 0.0 2.9 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 CAM37439.1 - 0.0089 15.9 1.3 0.39 10.8 0.0 3.8 4 1 1 5 5 5 1 EF-hand domain zinc_ribbon_2 PF13240.6 CAM37439.1 - 0.46 10.3 8.9 0.5 10.2 2.0 3.7 3 1 0 3 3 3 0 zinc-ribbon domain BBL5 PF07289.11 CAM37441.1 - 1.7e-130 435.0 0.0 1.9e-130 434.8 0.0 1.0 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein Vps36_ESCRT-II PF11605.8 CAM37441.1 - 0.00055 20.1 0.0 0.16 12.2 0.0 2.3 2 0 0 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 Voldacs PF03517.13 CAM37441.1 - 0.00072 19.7 0.2 0.56 10.3 0.0 2.7 2 0 0 2 2 2 2 Regulator of volume decrease after cellular swelling bPH_3 PF14470.6 CAM37441.1 - 0.026 14.9 0.0 7 7.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial PH domain PH_TFIIH PF08567.11 CAM37441.1 - 0.055 13.8 0.0 2.2 8.6 0.0 2.5 2 0 0 2 2 2 0 TFIIH p62 subunit, N-terminal domain LRR_6 PF13516.6 CAM37443.2 - 2.2e-21 74.0 23.8 0.15 12.2 0.1 11.3 11 0 0 11 11 11 9 Leucine Rich repeat LRR_4 PF12799.7 CAM37443.2 - 5e-09 36.3 12.2 0.28 11.7 0.0 7.7 6 3 2 8 8 8 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CAM37443.2 - 8.7e-08 31.7 4.5 6.9 7.6 0.0 7.7 8 1 0 8 8 8 2 Leucine Rich Repeat LRR_8 PF13855.6 CAM37443.2 - 2e-05 24.3 15.8 0.87 9.4 0.2 6.8 6 2 0 6 6 6 3 Leucine rich repeat DUF962 PF06127.11 CAM37444.1 - 1.8e-24 85.6 0.2 2.1e-24 85.4 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF962) MerC PF03203.14 CAM37444.1 - 0.013 15.9 2.1 0.02 15.3 2.1 1.4 1 1 0 1 1 1 0 MerC mercury resistance protein BAAT_C PF08840.11 CAM37444.1 - 0.019 14.9 0.1 0.022 14.7 0.1 1.1 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal TMEM65 PF10507.9 CAM37444.1 - 0.027 14.4 2.2 0.064 13.2 2.2 1.7 1 1 1 2 2 2 0 Transmembrane protein 65 Phage_holin_2_4 PF16082.5 CAM37444.1 - 0.068 12.9 2.1 0.1 12.4 2.1 1.3 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DUF962 PF06127.11 CAM37445.1 - 8.1e-26 90.0 0.1 9.1e-26 89.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF962) UPF0126 PF03458.13 CAM37445.1 - 0.0082 16.0 2.0 0.013 15.4 2.0 1.3 1 0 0 1 1 1 1 UPF0126 domain Ydr279_N PF17745.1 CAM37446.1 - 3.3e-06 27.3 0.0 8.1e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain LRR_8 PF13855.6 CAM37448.2 - 6.6e-23 80.2 24.9 0.00043 20.0 1.3 9.9 3 3 10 14 14 14 11 Leucine rich repeat LRR_4 PF12799.7 CAM37448.2 - 8.1e-23 80.1 20.5 0.033 14.6 0.1 11.2 5 2 6 14 14 14 10 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 CAM37448.2 - 0.0014 18.9 0.5 0.0014 18.9 0.5 2.5 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain TMEM191C PF15194.6 CAM37448.2 - 0.43 10.8 10.6 5.1 7.3 1.3 3.6 1 1 1 3 3 3 0 TMEM191C family LRRNT_2 PF08263.12 CAM37449.1 - 0.00054 20.2 0.5 0.00054 20.2 0.5 2.1 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain TetR_C_30 PF17939.1 CAM37450.2 - 4 7.7 9.8 0.28 11.4 0.3 3.6 5 0 0 5 5 5 0 Tetracyclin repressor-like, C-terminal domain DnaJ PF00226.31 CAM37451.1 - 6.5e-14 51.8 0.0 1.4e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain zf-C3HC4_3 PF13920.6 CAM37451.1 - 1.8 8.5 16.0 3.5 7.6 16.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PDZ PF00595.24 CAM37452.2 - 0.013 15.8 0.0 0.038 14.4 0.0 1.7 1 0 0 1 1 1 0 PDZ domain PDZ_6 PF17820.1 CAM37452.2 - 0.027 14.3 0.0 0.074 12.9 0.0 1.7 1 0 0 1 1 1 0 PDZ domain PDZ_2 PF13180.6 CAM37452.2 - 0.049 13.9 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 PDZ domain Oxidored_FMN PF00724.20 CAM37454.1 - 9.2e-79 265.2 0.0 1.2e-78 264.7 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 CAM37454.1 - 0.04 13.3 0.0 9.7 5.6 0.0 2.7 2 1 1 3 3 3 0 Xylose isomerase-like TIM barrel His_biosynth PF00977.21 CAM37454.1 - 0.059 12.8 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein Oxidored_FMN PF00724.20 CAM37455.1 - 2.6e-133 444.6 0.0 3e-75 253.6 0.0 2.1 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family TmoB PF06234.12 CAM37455.1 - 0.11 12.6 0.6 6.6 6.9 0.2 2.6 2 0 0 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) CSD PF00313.22 CAM37459.1 - 0.00048 19.9 0.0 0.0099 15.7 0.0 2.4 2 0 0 2 2 2 1 'Cold-shock' DNA-binding domain ABC_tran PF00005.27 CAM37460.2 - 1.7e-11 44.8 0.1 6e-05 23.6 0.3 2.4 2 0 0 2 2 2 2 ABC transporter AAA_30 PF13604.6 CAM37460.2 - 0.0012 18.6 0.1 0.003 17.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CAM37460.2 - 0.0056 16.6 0.4 0.01 15.7 0.4 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 CAM37460.2 - 0.031 14.7 0.4 0.12 12.7 0.4 2.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CAM37460.2 - 0.058 13.7 0.0 0.53 10.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CAM37460.2 - 0.063 13.0 0.2 0.15 11.9 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_membrane PF00664.23 CAM37460.2 - 0.092 12.4 0.2 0.17 11.5 0.2 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region AAA_21 PF13304.6 CAM37460.2 - 0.17 11.7 0.0 2.9 7.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Guanylate_kin PF00625.21 CAM37460.2 - 0.18 11.5 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Guanylate kinase DUF3835 PF12927.7 CAM37461.2 - 0.082 13.8 0.0 0.19 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3835) Mcl1_mid PF12341.8 CAM37463.1 - 1.7e-56 191.8 0.0 2.6e-56 191.2 0.0 1.3 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 CAM37463.1 - 0.12 13.3 3.2 14 6.7 0.2 4.5 4 0 0 4 4 4 0 WD domain, G-beta repeat DUF2121 PF09894.9 CAM37463.1 - 0.19 11.3 0.0 0.42 10.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2121) SNARE_assoc PF09335.11 CAM37464.1 - 5.9e-21 75.2 6.6 1.1e-20 74.4 6.2 1.7 2 0 0 2 2 2 1 SNARE associated Golgi protein zf-RING_UBOX PF13445.6 CAM37465.2 - 5e-08 32.8 6.4 5e-08 32.8 6.4 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CAM37465.2 - 7.8e-06 25.7 7.3 1.1e-05 25.3 4.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CAM37465.2 - 0.00014 21.6 8.0 0.00014 21.6 8.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CAM37465.2 - 0.00021 21.4 7.3 0.00021 21.4 7.3 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CAM37465.2 - 0.008 16.1 8.0 0.008 16.1 8.0 2.6 3 0 0 3 3 3 1 zinc-RING finger domain Peptidase_M1 PF01433.20 CAM37466.1 - 1.3e-47 162.2 0.0 2e-47 161.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CAM37466.1 - 3.4e-19 69.7 0.0 2.1e-14 54.2 0.0 2.2 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 CAM37466.1 - 3.3e-07 30.2 0.0 5.5e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Aminopep PF10023.9 CAM37466.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Putative aminopeptidase Prok-RING_2 PF14445.6 CAM37467.1 - 0.071 13.3 2.9 0.17 12.0 2.9 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 FYVE PF01363.21 CAM37467.1 - 1.3 9.2 8.8 4.1 7.6 0.5 2.4 2 0 0 2 2 2 0 FYVE zinc finger FTCD_C PF04961.12 CAM37468.1 - 0.073 12.8 1.1 0.18 11.6 1.1 1.6 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Ydr279_N PF17745.1 CAM37469.2 - 1.3e-05 25.3 0.0 3.3e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain RNase_H2-Ydr279 PF09468.10 CAM37469.2 - 0.0038 17.4 0.0 0.007 16.6 0.0 1.4 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain KH_6 PF15985.5 CAM37470.1 - 3.3e-12 46.6 0.3 5.3e-11 42.7 0.0 2.6 2 0 0 2 2 2 1 KH domain FAA_hydrolase_N PF09298.11 CAM37472.1 - 0.21 11.8 0.9 14 5.9 0.1 2.6 1 1 0 2 2 2 0 Fumarylacetoacetase N-terminal SNF2_N PF00176.23 CAM37473.1 - 9.5e-22 77.2 0.0 2e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Tet_JBP PF12851.7 CAM37473.1 - 2.3e-21 76.5 0.2 4e-17 62.6 0.0 2.3 1 1 1 2 2 2 2 Oxygenase domain of the 2OGFeDO superfamily Helicase_C PF00271.31 CAM37473.1 - 1.7e-13 50.9 0.1 3.9e-13 49.7 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAM37473.1 - 1.2e-09 38.4 0.0 3.8e-09 36.8 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CAM37473.1 - 0.0026 17.0 0.6 0.0045 16.2 0.6 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 CAM37473.1 - 0.025 14.3 0.0 0.15 11.8 0.0 2.3 2 1 0 2 2 2 0 DEAD/DEAH box helicase DUF2095 PF09868.9 CAM37473.1 - 0.033 14.2 0.0 0.093 12.7 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) DUF4279 PF14106.6 CAM37473.1 - 0.087 13.0 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) Arf PF00025.21 CAM37475.1 - 0.00037 20.0 0.0 0.0009 18.7 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_28 PF13521.6 CAM37475.1 - 0.0067 16.7 0.3 0.021 15.1 0.2 1.8 2 0 0 2 2 2 1 AAA domain DHHC PF01529.20 CAM37476.1 - 2.9e-23 82.5 13.9 2.9e-23 82.5 13.9 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase PIG-P PF08510.12 CAM37476.1 - 0.037 13.9 0.4 7.2 6.6 0.0 2.8 2 1 0 2 2 2 0 PIG-P Wzy_C PF04932.15 CAM37476.1 - 2.3 7.9 8.0 0.74 9.4 2.1 2.1 2 0 0 2 2 2 0 O-Antigen ligase Oxidored_q2 PF00420.24 CAM37476.1 - 8.9 6.0 9.3 0.12 12.0 0.7 2.3 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L PRP1_N PF06424.12 CAM37477.1 - 0.16 12.3 0.2 0.16 12.3 0.2 1.7 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal DnaJ PF00226.31 CAM37478.1 - 0.0021 18.2 0.0 0.0048 17.0 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain CH PF00307.31 CAM37479.1 - 0.021 15.0 0.0 0.069 13.3 0.0 1.9 1 0 0 1 1 1 0 Calponin homology (CH) domain Phage_GP20 PF06810.11 CAM37479.1 - 0.066 13.0 5.1 0.14 11.9 5.1 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF4061 PF13270.6 CAM37479.1 - 0.12 12.7 3.2 3.6 8.0 3.4 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) BORCS8 PF10167.9 CAM37479.1 - 0.3 11.1 3.3 0.65 9.9 2.0 2.3 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 GGDEF_2 PF17853.1 CAM37479.1 - 0.76 10.0 3.6 0.57 10.5 0.1 2.7 3 0 0 3 3 3 0 GGDEF-like domain GrpE PF01025.19 CAM37479.1 - 1.8 8.2 6.7 5.3 6.7 6.7 1.8 1 0 0 1 1 1 0 GrpE DnaJ PF00226.31 CAM37480.1 - 1.4e-12 47.6 0.9 2.6e-12 46.7 0.9 1.5 1 0 0 1 1 1 1 DnaJ domain IU_nuc_hydro PF01156.19 CAM37482.1 - 1.6e-68 231.6 0.0 1.9e-68 231.3 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase MOZ_SAS PF01853.18 CAM37483.1 - 7.8e-62 208.1 0.0 1.3e-61 207.4 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CAM37483.1 - 1.1e-08 34.5 0.4 5.2e-05 22.8 0.1 2.5 2 0 0 2 2 2 2 MYST family zinc finger domain Tudor-knot PF11717.8 CAM37483.1 - 1.4e-08 34.5 0.5 3.7e-08 33.1 0.1 1.9 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 CAM37483.1 - 0.0014 19.0 0.0 0.0041 17.5 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CAM37483.1 - 0.034 14.4 0.0 0.094 12.9 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family zf-Di19 PF05605.12 CAM37483.1 - 0.25 11.7 5.2 1.9 8.8 0.8 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Ribosomal_L12 PF00542.19 CAM37484.1 - 3.1e-16 59.4 3.6 3.1e-16 59.4 3.6 1.7 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain PSII_Pbs27 PF13326.6 CAM37484.1 - 0.021 15.1 5.7 0.07 13.5 2.5 2.1 2 0 0 2 2 2 0 Photosystem II Pbs27 Ribosomal_L12_N PF16320.5 CAM37484.1 - 1.8 8.4 0.0 1.8 8.4 0.0 2.9 3 0 0 3 3 3 0 Ribosomal protein L7/L12 dimerisation domain Chromo PF00385.24 CAM37485.1 - 0.0084 16.0 0.1 0.016 15.1 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Thioredoxin_8 PF13905.6 CAM37488.1 - 1.7e-08 34.7 0.2 2.5e-08 34.1 0.2 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 CAM37488.1 - 0.00046 20.1 0.0 0.00062 19.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CAM37488.1 - 0.0039 16.9 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Redoxin BBIP10 PF14777.6 CAM37489.1 - 3.5e-21 74.5 3.8 5.9e-21 73.8 3.8 1.3 1 0 0 1 1 1 1 Cilia BBSome complex subunit 10 DUF4201 PF13870.6 CAM37490.2 - 3.1e-30 105.2 8.8 3.1e-30 105.2 8.8 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF4201) bZIP_1 PF00170.21 CAM37490.2 - 0.053 13.6 1.1 0.053 13.6 1.1 4.0 4 0 0 4 4 4 0 bZIP transcription factor Csm1_N PF18504.1 CAM37490.2 - 0.28 11.5 18.7 0.37 11.2 2.7 4.3 3 1 1 4 4 4 0 Csm1 N-terminal domain MCM_N PF14551.6 CAM37490.2 - 0.43 11.2 3.0 2.7 8.6 0.1 2.9 3 0 0 3 3 3 0 MCM N-terminal domain APC_N_CC PF16689.5 CAM37490.2 - 3 8.0 6.2 6.4 6.9 2.7 3.0 2 1 1 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain PX PF00787.24 CAM37491.2 - 2.9e-09 36.9 0.1 1.8e-08 34.4 0.0 2.3 3 0 0 3 3 3 1 PX domain Sec5 PF15469.6 CAM37492.1 - 6e-05 22.9 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component Sec5 HIT PF01230.23 CAM37493.1 - 2.6e-23 82.6 0.0 3.4e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CAM37493.1 - 1.6e-12 47.9 0.0 2.2e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 CAM37493.1 - 0.0012 18.7 2.4 0.0017 18.2 1.3 1.9 2 1 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 RF3_C PF16658.5 CAM37493.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.3 1 1 0 1 1 1 0 Class II release factor RF3, C-terminal domain YcxB PF14317.6 CAM37493.1 - 0.12 12.1 0.0 23 4.8 0.0 2.8 2 1 1 3 3 3 0 YcxB-like protein TRAP-gamma PF07074.12 CAM37494.1 - 1.9e-08 34.0 2.2 0.00087 18.9 0.1 2.1 2 0 0 2 2 2 2 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF4386 PF14329.6 CAM37494.1 - 0.057 13.3 1.2 0.096 12.6 1.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4386) DUF2569 PF10754.9 CAM37494.1 - 0.11 13.0 2.5 0.15 12.5 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) VWA_3 PF13768.6 CAM37495.1 - 3.7e-08 33.5 0.1 9.2e-08 32.2 0.1 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 CAM37495.1 - 0.00075 19.3 0.1 0.002 18.0 0.1 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain Med3 PF11593.8 CAM37497.2 - 1 8.5 4.9 1.6 7.8 4.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Epimerase PF01370.21 CAM37498.1 - 1e-08 34.9 0.1 0.0041 16.6 0.1 2.4 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 CAM37498.1 - 0.00019 20.7 0.1 0.017 14.3 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 CAM37498.1 - 0.00023 21.1 0.9 0.11 12.4 0.2 2.3 2 0 0 2 2 2 2 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 CAM37498.1 - 0.0088 15.5 0.5 0.027 13.8 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 CAM37498.1 - 0.038 13.1 0.2 5.4 6.0 0.0 2.5 2 1 0 2 2 2 0 RmlD substrate binding domain Proteasome PF00227.26 CAM37500.1 - 6.6e-51 172.5 0.0 8.8e-51 172.1 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CAM37500.1 - 4.3e-13 48.7 0.3 7.3e-13 47.9 0.3 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF2064 PF09837.9 CAM37500.1 - 0.09 12.6 0.0 0.25 11.2 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) AA_permease_2 PF13520.6 CAM37501.1 - 3e-35 121.9 39.7 4.6e-35 121.3 39.5 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CAM37501.1 - 1.3e-09 37.2 37.4 4.1e-09 35.5 37.4 1.8 1 1 0 1 1 1 1 Amino acid permease Aa_trans PF01490.18 CAM37502.1 - 2.8e-24 85.6 18.3 3.8e-24 85.2 18.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein IPK PF03770.16 CAM37503.1 - 3.6e-42 144.5 0.1 7.5e-42 143.4 0.1 1.6 1 0 0 1 1 1 1 Inositol polyphosphate kinase Thr_synth_N PF14821.6 CAM37504.1 - 2.1e-13 50.3 0.1 7.1e-13 48.6 0.0 2.0 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 CAM37504.1 - 3.3e-11 43.2 0.0 7.3e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme zf-CW PF07496.15 CAM37505.1 - 0.003 17.5 6.4 0.003 17.5 6.4 1.8 2 0 0 2 2 2 1 CW-type Zinc Finger Bromodomain PF00439.25 CAM37505.1 - 0.11 12.6 0.1 1.1 9.4 0.1 2.1 1 1 0 1 1 1 0 Bromodomain ABC_tran_CTD PF16326.5 CAM37506.2 - 0.34 11.2 2.1 0.85 9.9 2.1 1.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain Choline_transpo PF04515.12 CAM37507.1 - 2.2e-52 178.3 39.5 2.2e-52 178.3 39.5 1.8 2 0 0 2 2 2 1 Plasma-membrane choline transporter JSRP PF15312.6 CAM37507.1 - 7.6 6.5 6.4 4.1 7.4 0.2 2.8 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein ATP-synt_D PF01813.17 CAM37510.1 - 0.1 12.4 0.1 11 5.7 0.0 2.1 2 0 0 2 2 2 0 ATP synthase subunit D UTP25 PF06862.12 CAM37511.2 - 2.7e-110 369.4 0.5 4.7e-101 338.9 0.0 2.1 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Dzip-like_N PF13815.6 CAM37512.1 - 3.1e-40 136.8 1.8 3.1e-40 136.8 1.8 2.1 3 0 0 3 3 3 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-Di19 PF05605.12 CAM37512.1 - 0.00011 22.5 0.1 0.00022 21.4 0.1 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 CAM37512.1 - 0.011 16.5 1.0 0.025 15.4 1.0 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CAM37512.1 - 0.054 13.8 0.6 0.28 11.6 0.1 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) HCR PF07111.12 CAM37512.1 - 0.091 10.8 2.9 3.2 5.7 1.0 2.3 2 0 0 2 2 2 0 Alpha helical coiled-coil rod protein (HCR) zf-C2H2 PF00096.26 CAM37512.1 - 0.41 11.2 1.3 0.87 10.2 1.3 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF4140 PF13600.6 CAM37512.1 - 5.9 7.4 6.7 6 7.4 0.1 3.3 4 0 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) OrsD PF12013.8 CAM37512.1 - 7.5 7.0 5.8 1.7 9.1 0.0 2.8 3 0 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D mRNA_triPase PF02940.15 CAM37513.1 - 5.7e-07 29.5 0.0 0.022 14.5 0.0 2.9 3 0 0 3 3 3 2 mRNA capping enzyme, beta chain Pyr_redox_2 PF07992.14 CAM37514.1 - 3.3e-16 59.4 0.0 1.2e-14 54.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CAM37514.1 - 2.3e-09 37.7 0.0 6.9e-06 26.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CAM37514.1 - 8e-07 28.4 0.0 0.00081 18.5 0.0 3.1 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 CAM37514.1 - 3.6e-06 27.1 0.0 0.023 14.7 0.0 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 CAM37514.1 - 1.4e-05 25.3 0.8 0.079 13.2 0.0 2.9 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CAM37514.1 - 2.1e-05 24.3 0.0 0.073 12.6 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 CAM37514.1 - 0.00073 18.8 0.0 0.003 16.8 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 CAM37514.1 - 0.0012 18.2 0.0 0.019 14.2 0.0 2.2 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 CAM37514.1 - 0.0065 15.6 0.0 2 7.4 0.0 2.8 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 CAM37514.1 - 0.034 13.4 0.1 0.29 10.3 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.6 CAM37514.1 - 0.052 14.0 0.0 15 6.1 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 CAM37514.1 - 0.16 10.8 0.0 11 4.7 0.0 2.4 3 0 0 3 3 3 0 Tryptophan halogenase CS PF04969.16 CAM37515.1 - 8.1e-16 58.8 0.0 1.4e-15 58.1 0.0 1.4 1 0 0 1 1 1 1 CS domain Nudc_N PF14050.6 CAM37515.1 - 6.2e-14 51.7 0.2 1.4e-13 50.6 0.2 1.6 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. Borrelia_P83 PF05262.11 CAM37515.1 - 0.00011 20.8 14.4 0.00014 20.5 14.4 1.1 1 0 0 1 1 1 1 Borrelia P83/100 protein Hid1 PF12722.7 CAM37515.1 - 0.016 13.3 1.9 0.021 13.0 1.9 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.16 CAM37515.1 - 6.7 6.7 8.5 0.38 10.8 3.0 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Cys_Met_Meta_PP PF01053.20 CAM37516.1 - 1.1e-115 386.3 0.0 1.4e-115 385.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 CAM37516.1 - 0.00011 21.6 0.0 0.00019 20.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CAM37516.1 - 0.054 12.8 0.3 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 CAM37516.1 - 0.12 11.6 0.1 0.29 10.4 0.1 1.6 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family UDPGT PF00201.18 CAM37517.1 - 9.4e-30 103.9 0.0 1.6e-29 103.1 0.0 1.4 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Amastin PF07344.11 CAM37518.1 - 1.4e-07 31.5 13.0 1.4e-07 31.5 13.0 2.0 1 1 1 2 2 2 1 Amastin surface glycoprotein DUF1361 PF07099.11 CAM37518.1 - 3 7.8 13.1 0.56 10.2 9.2 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1361) Amastin PF07344.11 CAM37519.1 - 1.4e-07 31.5 13.1 1.4e-07 31.5 13.1 2.0 1 1 0 2 2 2 1 Amastin surface glycoprotein DUF1361 PF07099.11 CAM37519.1 - 5.2 7.0 13.8 0.76 9.7 9.6 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1361) Ion_trans_2 PF07885.16 CAM37521.1 - 1.1e-08 34.9 7.0 1.1e-08 34.9 7.0 2.0 2 0 0 2 2 2 1 Ion channel IQ PF00612.27 CAM37521.1 - 0.03 14.1 0.1 0.1 12.4 0.1 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif Ion_trans_2 PF07885.16 CAM37522.1 - 2.7e-10 40.1 7.1 2.7e-10 40.1 7.1 2.2 2 0 0 2 2 2 1 Ion channel Lig_chan PF00060.26 CAM37522.1 - 0.0086 15.9 4.7 0.0086 15.9 4.7 2.1 2 1 0 2 2 2 1 Ligand-gated ion channel Ion_trans PF00520.31 CAM37522.1 - 0.15 11.3 21.1 0.6 9.3 21.1 2.0 1 1 0 1 1 1 0 Ion transport protein T2SSM PF04612.12 CAM37523.1 - 0.00019 21.5 0.7 0.0011 19.0 0.0 2.4 3 0 0 3 3 3 1 Type II secretion system (T2SS), protein M DUF3496 PF12001.8 CAM37523.1 - 0.0055 17.1 0.2 0.012 16.0 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3496) TSC22 PF01166.18 CAM37523.1 - 0.12 12.8 1.1 4.1 7.8 0.2 2.4 2 0 0 2 2 2 0 TSC-22/dip/bun family GPR15L PF15854.5 CAM37523.1 - 0.54 10.5 3.1 1.2 9.4 0.1 2.6 2 0 0 2 2 2 0 G-protein coupled receptor ligand 15 WD40 PF00400.32 CAM37524.1 - 5.2e-22 77.7 21.1 0.0027 18.5 0.0 10.2 11 0 0 11 11 11 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM37524.1 - 3e-07 30.7 0.0 38 4.7 0.0 7.9 7 1 1 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 CAM37524.1 - 3.5e-06 27.3 0.1 7.1e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.8 CAM37524.1 - 0.088 11.4 1.0 3.4 6.2 0.2 2.9 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Complex1_LYR PF05347.15 CAM37525.1 - 0.00098 19.1 0.4 0.0017 18.4 0.4 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CAM37525.1 - 0.076 13.8 0.2 0.13 13.0 0.2 1.4 1 0 0 1 1 1 0 Complex1_LYR-like TetR_C_33 PF13305.6 CAM37526.1 - 0.023 15.4 2.2 0.25 12.1 0.1 3.4 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain DUF3678 PF12435.8 CAM37526.1 - 0.027 13.8 0.4 0.18 11.2 0.4 2.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) SpoU_methylase PF00588.19 CAM37527.1 - 2.2e-10 40.8 0.0 0.00027 21.1 0.0 2.4 2 0 0 2 2 2 2 SpoU rRNA Methylase family Nrap_D2 PF17403.2 CAM37527.1 - 0.034 13.9 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Spt5_N PF11942.8 CAM37528.1 - 0.0078 17.2 5.9 0.0078 17.2 5.9 2.7 3 0 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal Pes-10 PF07149.11 CAM37528.1 - 1.7 7.6 3.7 2.6 7.0 3.7 1.2 1 0 0 1 1 1 0 Pes-10 CDC45 PF02724.14 CAM37528.1 - 2.7 6.2 10.5 0.034 12.5 3.0 1.5 2 0 0 2 2 2 0 CDC45-like protein EZH2_N PF18601.1 CAM37529.1 - 0.077 13.3 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 EZH2 N-terminal domain zf-LSD1 PF06943.12 CAM37530.1 - 1.7e-07 30.9 8.6 1.7e-07 30.9 8.6 2.9 2 1 0 2 2 2 1 LSD1 zinc finger zf-NADH-PPase PF09297.11 CAM37530.1 - 0.2 11.4 6.7 0.18 11.5 3.9 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DZR PF12773.7 CAM37530.1 - 1.2 9.2 12.3 0.071 13.2 4.7 2.4 2 1 1 3 3 3 0 Double zinc ribbon ELO PF01151.18 CAM37531.1 - 1.9e-39 135.7 10.8 2.2e-39 135.5 10.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 CAM37532.1 - 2.3e-65 220.6 17.1 2.7e-65 220.4 17.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 CAM37533.1 - 6.9e-62 209.2 14.0 8e-62 209.0 14.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 CAM37534.1 - 9.9e-63 212.0 12.7 1.1e-62 211.8 12.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 CAM37535.1 - 2.8e-69 233.4 5.1 3.3e-69 233.2 5.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 CAM37536.2 - 9.3e-81 271.0 21.3 1.1e-80 270.8 21.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family CrgA PF06781.12 CAM37536.2 - 0.11 12.6 1.6 0.43 10.7 0.1 2.4 2 0 0 2 2 2 0 Cell division protein CrgA ELO PF01151.18 CAM37538.1 - 4.6e-85 285.1 18.8 5.9e-85 284.8 18.8 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family ODV-E18 PF10717.9 CAM37538.1 - 0.33 10.8 3.2 2.4 8.1 0.0 2.9 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 ELO PF01151.18 CAM37539.1 - 6.8e-69 232.2 22.4 8e-69 231.9 22.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 CAM37540.1 - 2e-71 240.5 22.5 2.4e-71 240.2 22.5 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 CAM37541.1 - 4.5e-79 265.5 21.0 5.6e-79 265.2 21.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Ribosomal_L21p PF00829.21 CAM37545.1 - 1.7e-19 70.0 0.0 2.2e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein PsbP PF01789.16 CAM37545.1 - 0.035 14.3 0.1 0.065 13.4 0.1 1.4 1 0 0 1 1 1 0 PsbP Pox_A_type_inc PF04508.12 CAM37546.2 - 0.34 10.8 4.1 2 8.4 4.1 2.4 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat TRAP_alpha PF03896.16 CAM37547.1 - 0.087 12.0 0.6 0.17 11.0 0.6 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF1682 PF07946.14 CAM37547.1 - 0.16 11.1 2.5 0.28 10.4 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF4201 PF13870.6 CAM37549.2 - 2.3e-30 105.7 16.6 2.3e-30 105.7 16.6 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF4201) JIP_LZII PF16471.5 CAM37549.2 - 0.031 14.4 1.4 0.031 14.4 1.4 5.0 4 2 1 5 5 5 0 JNK-interacting protein leucine zipper II SlyX PF04102.12 CAM37549.2 - 0.58 10.8 0.0 0.58 10.8 0.0 6.5 5 2 2 7 7 7 0 SlyX Phycoerythr_ab PF02972.14 CAM37549.2 - 1.1 9.1 3.0 2.6 7.9 0.7 2.8 2 0 0 2 2 2 0 Phycoerythrin, alpha/beta chain LURAP PF14854.6 CAM37549.2 - 4.9 7.1 7.5 4.4 7.3 0.2 3.2 3 0 0 3 3 3 0 Leucine rich adaptor protein DUF16 PF01519.16 CAM37549.2 - 7 7.2 0.0 7 7.2 0.0 5.5 4 1 2 6 6 6 0 Protein of unknown function DUF16 Pkinase PF00069.25 CAM37550.1 - 1.1e-41 143.0 0.0 1.2e-22 80.6 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM37550.1 - 3.2e-12 46.3 0.0 9.8e-08 31.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CAM37550.1 - 0.00044 20.3 0.0 0.00076 19.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CAM37550.1 - 0.035 13.7 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 CAM37550.1 - 0.05 13.2 0.0 0.077 12.6 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase SNF2_N PF00176.23 CAM37551.1 - 1.6e-57 194.9 0.0 3.7e-57 193.6 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CAM37551.1 - 9.3e-20 71.0 0.0 8.6e-19 67.9 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAM37551.1 - 7.9e-08 32.5 0.0 3e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit YebO PF13974.6 CAM37551.1 - 0.81 9.8 4.7 0.29 11.3 0.2 2.6 2 0 0 2 2 2 0 YebO-like protein AChE_tetra PF08674.10 CAM37551.1 - 2.3 8.0 3.7 0.95 9.2 0.1 2.2 2 0 0 2 2 2 0 Acetylcholinesterase tetramerisation domain DUF1935 PF09149.10 CAM37552.1 - 1.1e-39 134.9 0.4 1.3e-39 134.7 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.10 CAM37553.1 - 6.9e-40 135.6 0.4 7.7e-40 135.4 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) PP2C PF00481.21 CAM37557.1 - 4.8e-48 164.0 0.0 1.8e-47 162.1 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CAM37557.1 - 7.9e-07 28.9 0.1 7.9e-07 28.9 0.1 2.9 2 1 0 2 2 2 1 Protein phosphatase 2C CAP_N PF01213.19 CAM37557.1 - 8.3 5.8 5.6 15 4.9 0.9 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal GSH_synth_ATP PF03917.17 CAM37558.1 - 9.1e-72 241.9 0.1 1.5e-71 241.2 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 CAM37558.1 - 5.8e-31 107.0 0.2 1.2e-30 106.0 0.2 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase DNA_pol_A PF00476.20 CAM37559.2 - 1.5e-39 136.2 0.0 2.1e-38 132.4 0.0 2.4 2 1 0 2 2 2 1 DNA polymerase family A DUF4315 PF14193.6 CAM37560.1 - 0.018 15.1 2.0 0.032 14.2 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) Pesticin PF16754.5 CAM37560.1 - 0.12 12.4 0.1 8.8 6.3 0.0 2.4 2 0 0 2 2 2 0 Bacterial toxin homologue of phage lysozyme, C-term Arg_decarbox_C PF17944.1 CAM37560.1 - 0.56 10.8 4.4 2 9.0 0.1 3.2 3 0 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension SlyX PF04102.12 CAM37560.1 - 1 10.0 9.8 19 6.0 0.0 4.1 3 1 0 3 3 3 0 SlyX Serine_rich PF08824.10 CAM37560.1 - 2.9 7.9 8.5 9.9 6.1 0.3 3.3 3 0 0 3 3 3 0 Serine rich protein interaction domain DUF1451 PF07295.11 CAM37560.1 - 7.9 6.5 9.0 1.1 9.2 0.5 3.0 3 0 0 3 3 3 0 Zinc-ribbon containing domain PBP1_TM PF14812.6 CAM37561.1 - 3.6 8.0 6.9 8.5 6.8 6.9 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_L16 PF00252.18 CAM37562.1 - 3e-16 59.6 0.0 3.6e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e PAP_assoc PF03828.19 CAM37563.1 - 1.8e-16 60.1 0.0 3.2e-11 43.3 0.0 2.9 3 0 0 3 3 3 2 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CAM37563.1 - 0.0095 16.2 0.0 0.35 11.2 0.0 2.4 2 0 0 2 2 2 1 Nucleotidyltransferase domain zf-MYST PF17772.1 CAM37563.1 - 0.038 13.6 0.1 0.075 12.7 0.1 1.4 1 0 0 1 1 1 0 MYST family zinc finger domain PRK PF00485.18 CAM37565.1 - 4.9e-06 26.4 0.0 0.029 14.1 0.0 2.2 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 CAM37565.1 - 3.9e-05 24.2 0.0 0.038 14.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 CAM37565.1 - 0.0036 16.9 0.0 0.0059 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 CAM37565.1 - 0.0068 16.3 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain ABC_tran PF00005.27 CAM37565.1 - 0.0088 16.6 0.0 0.014 15.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter RNA_helicase PF00910.22 CAM37565.1 - 0.013 15.9 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 CAM37565.1 - 0.013 14.7 0.1 0.028 13.7 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.6 CAM37565.1 - 0.018 15.4 0.0 0.032 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain dNK PF01712.19 CAM37565.1 - 0.023 14.6 0.0 7.3 6.4 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA PF00004.29 CAM37565.1 - 0.025 15.0 0.0 0.057 13.9 0.0 1.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 CAM37565.1 - 0.027 13.6 0.0 0.048 12.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 CAM37565.1 - 0.043 13.7 0.0 0.12 12.3 0.0 1.6 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 CAM37565.1 - 0.066 13.3 0.0 0.15 12.1 0.0 1.6 2 0 0 2 2 1 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 CAM37565.1 - 0.073 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 CAM37565.1 - 0.11 12.8 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CAM37565.1 - 0.11 12.7 0.0 1 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CAM37565.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Ploopntkinase3 PF18751.1 CAM37565.1 - 0.15 12.0 0.0 0.58 10.1 0.0 1.8 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_17 PF13207.6 CAM37565.1 - 0.18 12.2 0.0 5.1 7.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Mito_carr PF00153.27 CAM37567.1 - 1.2e-25 89.3 0.3 1.4e-11 44.1 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein TT_ORF2 PF02957.15 CAM37567.1 - 0.16 12.9 0.2 1.3 9.9 0.0 2.0 2 0 0 2 2 2 0 TT viral ORF2 Mito_carr PF00153.27 CAM37568.1 - 4.7e-07 29.7 0.0 0.0047 16.8 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein Sulfotransfer_3 PF13469.6 CAM37571.1 - 8.2e-06 26.4 0.0 1.4e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family SRA1 PF07304.11 CAM37571.1 - 0.018 14.9 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) DUF202 PF02656.15 CAM37572.1 - 2.2e-16 60.0 0.7 1.7e-15 57.2 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4199 PF13858.6 CAM37572.1 - 0.0099 16.3 0.4 0.014 15.9 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4199) COQ9 PF08511.11 CAM37574.1 - 4e-05 23.3 0.0 0.0013 18.5 0.0 2.4 2 0 0 2 2 2 1 COQ9 AAA_6 PF12774.7 CAM37575.1 - 9.2e-142 471.8 0.5 1.1e-139 465.0 0.0 3.4 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CAM37575.1 - 1.6e-108 363.4 0.2 1.6e-108 363.4 0.2 3.1 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 CAM37575.1 - 8.4e-93 310.4 0.0 2.5e-92 308.9 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CAM37575.1 - 4.8e-82 275.6 1.5 1.3e-81 274.2 0.0 2.6 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 CAM37575.1 - 8.9e-72 240.8 0.7 8.9e-72 240.8 0.7 2.4 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 CAM37575.1 - 1.1e-55 187.9 1.6 1.1e-50 171.7 0.0 4.4 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 CAM37575.1 - 2.1e-42 145.4 3.3 2.1e-42 145.4 3.3 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 CAM37575.1 - 2.2e-39 134.2 0.0 1.5e-36 125.1 0.0 3.6 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 CAM37575.1 - 7.8e-26 90.8 0.0 4.8e-25 88.3 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_AAA_lid PF17852.1 CAM37575.1 - 1.9e-17 63.5 0.3 8.2e-16 58.3 0.3 3.5 2 1 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CAM37575.1 - 2.2e-17 63.4 3.8 5.7e-05 23.1 0.0 6.3 6 2 0 6 6 6 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 CAM37575.1 - 2.3e-17 63.0 0.0 9.3e-17 61.1 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 CAM37575.1 - 1.8e-05 25.0 15.9 0.084 13.2 0.0 7.8 6 1 1 7 7 7 1 AAA domain AAA PF00004.29 CAM37575.1 - 0.00044 20.7 1.0 2 8.8 0.0 4.4 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 CAM37575.1 - 0.001 18.2 0.2 0.14 11.2 0.0 3.1 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_29 PF13555.6 CAM37575.1 - 0.0022 17.7 2.1 4.7 7.0 0.1 3.8 3 0 0 3 3 3 1 P-loop containing region of AAA domain DUF815 PF05673.13 CAM37575.1 - 0.0036 16.5 2.3 1.2 8.2 0.0 3.5 4 0 0 4 4 4 2 Protein of unknown function (DUF815) AAA_16 PF13191.6 CAM37575.1 - 0.0078 16.6 21.6 0.31 11.4 0.0 6.7 7 1 0 7 7 4 2 AAA ATPase domain AAA_18 PF13238.6 CAM37575.1 - 0.0078 16.8 1.0 5.1 7.7 0.0 4.4 4 0 0 4 4 3 1 AAA domain M16C_assoc PF08367.11 CAM37575.1 - 0.039 13.1 3.5 0.068 12.3 0.2 2.5 2 0 0 2 2 2 0 Peptidase M16C associated NKAIN PF05640.14 CAM37575.1 - 0.082 12.2 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Na,K-Atpase Interacting protein LMBR1 PF04791.16 CAM37575.1 - 0.29 10.0 2.0 0.64 8.9 2.0 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein Mg_chelatase PF01078.21 CAM37575.1 - 0.85 9.0 4.4 32 3.8 0.1 4.2 5 0 0 5 5 5 0 Magnesium chelatase, subunit ChlI DUF724 PF05266.14 CAM37575.1 - 1.2 8.9 10.5 17 5.2 5.9 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DASH_Spc34 PF08657.10 CAM37575.1 - 1.2 8.8 5.4 2.6 7.8 4.2 2.1 2 0 0 2 2 2 0 DASH complex subunit Spc34 Pkinase PF00069.25 CAM37576.1 - 1.4e-43 149.2 0.0 1.3e-42 146.0 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM37576.1 - 7.8e-17 61.4 0.0 9.4e-16 57.9 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase PBP_sp32 PF07222.12 CAM37576.1 - 0.22 11.0 3.4 0.47 9.9 3.4 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 LST1 PF05083.13 CAM37577.1 - 0.16 12.2 3.6 1 9.7 3.7 2.2 2 1 0 2 2 2 0 LST-1 protein PQ-loop PF04193.14 CAM37578.1 - 7.6e-26 89.7 5.3 2.4e-12 46.4 0.2 2.8 2 0 0 2 2 2 2 PQ loop repeat Kinesin PF00225.23 CAM37580.1 - 1.4e-104 349.6 0.0 1.4e-104 349.6 0.0 2.1 2 1 1 3 3 2 1 Kinesin motor domain HAMP_N3 PF18575.1 CAM37580.1 - 2.9e-25 87.6 11.2 1.1e+02 2.4 0.0 25.0 27 0 0 27 27 27 0 HAMP N-terminal domain 3 Microtub_bd PF16796.5 CAM37580.1 - 6.2e-21 74.9 0.0 1.7e-20 73.4 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding APG6_N PF17675.1 CAM37580.1 - 1.1e-19 71.3 331.3 0.017 15.6 9.8 22.2 1 1 23 24 24 22 20 Apg6 coiled-coil region ADIP PF11559.8 CAM37580.1 - 1.6e-18 67.3 235.6 0.046 13.8 3.0 24.8 1 1 21 24 24 23 20 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 CAM37580.1 - 8.3e-18 65.3 296.5 0.013 15.7 26.4 17.0 1 1 12 13 13 10 9 Autophagy protein 16 (ATG16) Flagellin_C PF00700.21 CAM37580.1 - 1.3e-16 60.7 91.3 14 6.2 0.1 25.2 15 5 14 30 30 29 0 Bacterial flagellin C-terminal helical region ZapB PF06005.12 CAM37580.1 - 6.3e-14 52.2 309.8 0.66 10.4 1.2 33.0 18 6 12 30 30 28 18 Cell division protein ZapB KASH_CCD PF14662.6 CAM37580.1 - 1e-11 45.1 212.9 0.06 13.2 9.6 14.8 1 1 14 17 17 14 13 Coiled-coil region of CCDC155 or KASH GAS PF13851.6 CAM37580.1 - 2.3e-11 43.4 216.1 0.017 14.5 13.5 15.6 1 1 18 19 19 17 15 Growth-arrest specific micro-tubule binding Myosin_tail_1 PF01576.19 CAM37580.1 - 6.9e-11 40.8 260.5 0.00028 18.9 43.6 8.2 1 1 5 7 7 6 5 Myosin tail DUF1664 PF07889.12 CAM37580.1 - 5.9e-10 39.3 89.3 1.2 9.2 0.3 18.2 2 2 27 29 29 28 5 Protein of unknown function (DUF1664) DUF3450 PF11932.8 CAM37580.1 - 3.8e-09 36.2 228.2 0.0075 15.6 3.1 18.5 1 1 20 22 22 20 17 Protein of unknown function (DUF3450) Spc7 PF08317.11 CAM37580.1 - 4.5e-09 35.6 238.4 0.044 12.7 7.5 15.3 1 1 16 17 17 16 13 Spc7 kinetochore protein Striatin PF08232.12 CAM37580.1 - 1e-07 32.7 252.9 1.6 9.3 1.0 29.7 1 1 26 27 27 25 16 Striatin family Wtap PF17098.5 CAM37580.1 - 4e-07 30.1 218.5 0.043 13.8 6.7 21.6 2 2 18 20 20 18 11 WTAP/Mum2p family DUF4201 PF13870.6 CAM37580.1 - 2.6e-06 27.3 224.2 0.62 9.8 2.9 26.4 1 1 30 31 31 29 16 Domain of unknown function (DUF4201) CENP-F_leu_zip PF10473.9 CAM37580.1 - 2.8e-06 27.4 209.1 0.0014 18.7 7.2 17.2 1 1 19 21 21 19 8 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 CAM37580.1 - 9.5e-06 25.7 306.9 1.8e-05 24.8 14.2 22.7 1 1 20 26 26 24 14 TPR/MLP1/MLP2-like protein DUF4472 PF14739.6 CAM37580.1 - 1.1e-05 26.1 217.0 0.47 11.2 2.4 22.8 1 1 24 26 26 23 19 Domain of unknown function (DUF4472) Taxilin PF09728.9 CAM37580.1 - 0.0013 18.0 180.1 0.0099 15.1 16.7 9.6 1 1 6 8 8 6 4 Myosin-like coiled-coil protein SHE3 PF17078.5 CAM37580.1 - 0.0022 17.7 152.3 0.074 12.7 4.0 14.2 1 1 10 12 12 10 9 SWI5-dependent HO expression protein 3 TMF_DNA_bd PF12329.8 CAM37580.1 - 0.099 12.7 227.3 2.2 8.3 1.1 30.8 2 2 30 34 34 31 0 TATA element modulatory factor 1 DNA binding NPL PF17800.1 CAM37580.1 - 0.26 11.9 1.5 3.3 8.3 1.3 3.2 2 0 0 2 2 1 0 Nucleoplasmin-like domain DUF4200 PF13863.6 CAM37580.1 - 0.39 11.1 215.1 0.12 12.8 3.8 17.1 1 1 18 20 20 17 0 Domain of unknown function (DUF4200) Filament PF00038.21 CAM37580.1 - 5.8 6.4 207.6 0.0059 16.2 23.3 10.2 1 1 4 8 8 7 0 Intermediate filament protein Kinesin PF00225.23 CAM37582.1 - 2.6e-75 253.4 0.0 9.4e-75 251.6 0.0 2.1 1 0 0 1 1 1 1 Kinesin motor domain UPF0242 PF06785.11 CAM37582.1 - 3.4e-13 50.1 375.7 0.24 11.5 10.8 24.1 3 3 22 26 26 25 19 Uncharacterised protein family (UPF0242) N-terminus MscS_porin PF12795.7 CAM37582.1 - 9.7e-13 48.2 353.2 0.0069 16.0 24.1 14.9 4 1 12 16 16 15 12 Mechanosensitive ion channel porin domain Spc7 PF08317.11 CAM37582.1 - 4e-11 42.3 364.5 0.0061 15.5 8.6 16.3 2 2 22 24 24 24 20 Spc7 kinetochore protein DUF745 PF05335.13 CAM37582.1 - 1.2e-06 28.4 306.5 0.0064 16.2 16.6 16.7 4 3 18 22 22 21 16 Protein of unknown function (DUF745) CENP-F_leu_zip PF10473.9 CAM37582.1 - 1.3e-05 25.3 396.7 0.11 12.5 25.3 17.7 3 3 16 19 19 18 12 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 CAM37582.1 - 5.7e-05 23.2 423.3 0.046 13.8 33.0 16.9 5 2 12 18 18 17 14 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 CAM37582.1 - 0.00049 20.4 26.5 0.00049 20.4 26.5 15.8 3 2 10 14 14 7 1 Autophagy protein 16 (ATG16) CCDC144C PF14915.6 CAM37582.1 - 0.21 10.7 306.9 0.027 13.6 46.3 11.2 3 2 8 11 11 10 0 CCDC144C protein coiled-coil region NPV_P10 PF05531.12 CAM37582.1 - 0.94 10.0 10.9 1.9e+02 2.6 0.8 8.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein TolA_bind_tri PF16331.5 CAM37582.1 - 1.1 9.3 317.1 0.21 11.7 4.0 35.9 4 2 46 50 50 50 0 TolA binding protein trimerisation DUF4201 PF13870.6 CAM37582.1 - 1.9 8.2 265.4 0.068 12.9 14.8 17.2 3 2 14 17 17 16 0 Domain of unknown function (DUF4201) CSD PF00313.22 CAM37584.1 - 7.1e-11 41.8 0.3 6.5e-06 25.9 0.1 3.9 4 0 0 4 4 4 2 'Cold-shock' DNA-binding domain S1-like PF14444.6 CAM37584.1 - 0.0071 16.3 1.0 0.83 9.6 0.0 3.7 4 0 0 4 4 4 1 S1-like Tub PF01167.18 CAM37585.1 - 3.2e-31 108.9 0.0 1.3e-29 103.7 0.0 2.5 2 1 0 2 2 2 2 Tub family Kinesin PF00225.23 CAM37587.1 - 3.4e-84 282.6 0.0 4.9e-84 282.1 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CAM37587.1 - 9.2e-23 80.8 0.0 3.9e-20 72.3 0.0 2.4 2 0 0 2 2 2 2 Microtubule binding p25-alpha PF05517.12 CAM37588.1 - 1.8e-38 132.1 2.6 2.3e-38 131.8 2.6 1.1 1 0 0 1 1 1 1 p25-alpha Spo0A_C PF08769.11 CAM37588.1 - 0.016 15.3 0.3 0.036 14.2 0.2 1.6 2 0 0 2 2 2 0 Sporulation initiation factor Spo0A C terminal ScsC_N PF18312.1 CAM37588.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain p25-alpha PF05517.12 CAM37589.1 - 2e-39 135.3 5.2 2.2e-39 135.1 5.2 1.0 1 0 0 1 1 1 1 p25-alpha Spo0A_C PF08769.11 CAM37589.1 - 0.014 15.5 0.1 0.021 14.9 0.1 1.3 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal UPF0242 PF06785.11 CAM37590.1 - 0.64 10.1 4.4 0.26 11.3 1.6 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF3808 PF10300.9 CAM37591.1 - 2.1e-42 145.5 0.8 4.3e-42 144.5 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) EAP30 PF04157.16 CAM37594.1 - 2e-62 210.6 6.9 3.6e-62 209.7 6.9 1.4 1 1 0 1 1 1 1 EAP30/Vps36 family MitMem_reg PF13012.6 CAM37594.1 - 0.07 13.6 0.4 0.44 11.0 0.1 2.1 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function HalX PF08663.10 CAM37594.1 - 0.11 12.9 0.4 0.27 11.6 0.4 1.7 1 0 0 1 1 1 0 HalX domain MerR-DNA-bind PF09278.11 CAM37594.1 - 0.28 11.7 4.5 0.79 10.3 4.5 1.7 1 0 0 1 1 1 0 MerR, DNA binding R3H-assoc PF13902.6 CAM37596.1 - 1.4e-17 64.3 0.3 2.9e-17 63.3 0.3 1.5 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.22 CAM37596.1 - 0.016 15.2 0.0 0.049 13.6 0.0 1.8 1 0 0 1 1 1 0 R3H domain C2 PF00168.30 CAM37597.1 - 0.034 14.4 0.0 4.6 7.6 0.0 3.6 2 1 0 2 2 2 0 C2 domain PTEN_C2 PF10409.9 CAM37598.1 - 8.4e-10 38.5 0.0 1.4e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 CAM37598.1 - 1.8e-08 34.3 0.1 3.2e-08 33.4 0.1 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CAM37598.1 - 0.00011 21.8 0.0 0.00022 20.9 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CAM37598.1 - 0.0024 17.9 0.1 0.0043 17.0 0.1 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CAM37598.1 - 0.026 14.6 0.1 0.047 13.8 0.1 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate CDKN3 PF05706.12 CAM37598.1 - 0.11 12.2 0.2 0.21 11.2 0.2 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) DUF1143 PF06608.11 CAM37599.1 - 0.022 14.8 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1143) 2-Hacid_dh_C PF02826.19 CAM37600.2 - 7e-45 152.6 0.0 1.2e-44 151.8 0.0 1.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 CAM37600.2 - 2.8e-06 27.5 0.0 8.2e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh PF00389.30 CAM37600.2 - 9.6e-05 22.1 0.0 0.00026 20.6 0.0 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CAM37600.2 - 0.00013 22.1 0.1 0.00029 21.0 0.1 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 CAM37600.2 - 0.00043 19.9 0.0 0.00078 19.0 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 CAM37600.2 - 0.00079 18.8 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.17 CAM37600.2 - 0.0034 17.9 0.2 0.015 15.9 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ELFV_dehydrog PF00208.21 CAM37600.2 - 0.061 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF2997 PF11211.8 CAM37600.2 - 0.062 13.1 0.0 0.19 11.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2997) Pyr_redox PF00070.27 CAM37600.2 - 0.07 13.7 0.1 0.16 12.5 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UPF0242 PF06785.11 CAM37601.1 - 1.4e-23 84.0 299.0 0.054 13.6 11.7 19.6 1 1 19 20 20 20 19 Uncharacterised protein family (UPF0242) N-terminus MscS_porin PF12795.7 CAM37601.1 - 1.5e-21 77.0 273.3 0.0091 15.6 23.1 11.9 1 1 16 17 17 17 17 Mechanosensitive ion channel porin domain DUF745 PF05335.13 CAM37601.1 - 3.3e-20 72.6 235.0 0.0048 16.6 17.3 12.6 1 1 17 18 18 18 17 Protein of unknown function (DUF745) Spc7 PF08317.11 CAM37601.1 - 4.4e-18 65.2 288.2 0.03 13.2 28.4 11.3 1 1 16 17 17 17 16 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 CAM37601.1 - 2.2e-17 63.4 303.0 0.0024 17.9 28.3 11.9 1 1 14 15 15 15 14 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 CAM37601.1 - 1e-13 51.5 334.6 5e-05 23.4 31.7 13.4 1 1 17 18 18 18 16 TPR/MLP1/MLP2-like protein CCDC144C PF14915.6 CAM37601.1 - 2.3e-10 40.1 240.2 0.063 12.4 41.1 8.1 1 1 7 9 9 9 9 CCDC144C protein coiled-coil region DUF4201 PF13870.6 CAM37601.1 - 4e-10 39.7 199.7 0.071 12.8 16.4 12.4 1 1 14 15 15 15 10 Domain of unknown function (DUF4201) HAP1_N PF04849.13 CAM37601.1 - 9e-10 38.2 244.8 1.3 8.2 11.4 12.4 1 1 11 12 12 12 8 HAP1 N-terminal conserved region TolA_bind_tri PF16331.5 CAM37601.1 - 5.3e-09 36.0 277.5 2.7 8.1 3.2 32.6 1 1 43 44 44 44 16 TolA binding protein trimerisation Fez1 PF06818.15 CAM37601.1 - 1.1e-06 29.3 263.8 0.54 10.7 28.7 10.6 1 1 10 11 11 8 2 Fez1 THOC7 PF05615.13 CAM37601.1 - 3.5e-06 27.3 309.3 3.7 7.8 4.7 24.9 1 1 22 24 24 24 18 Tho complex subunit 7 DUF2353 PF09789.9 CAM37601.1 - 5e-06 26.1 205.9 0.069 12.5 31.4 8.7 1 1 4 5 5 3 3 Uncharacterized coiled-coil protein (DUF2353) PRKG1_interact PF15898.5 CAM37601.1 - 0.00031 21.6 247.4 2.9 8.8 11.1 17.6 1 1 20 21 21 21 17 cGMP-dependent protein kinase interacting domain HOOK PF05622.12 CAM37601.1 - 0.015 13.5 274.0 1.5 6.9 25.7 10.6 1 1 10 12 12 12 0 HOOK protein ALIX_LYPXL_bnd PF13949.6 CAM37601.1 - 0.16 11.2 207.5 1.7 7.9 51.4 6.6 1 1 4 5 5 5 0 ALIX V-shaped domain binding to HIV Rootletin PF15035.6 CAM37601.1 - 0.39 10.7 276.3 5.7 6.9 6.9 17.1 1 1 19 20 20 20 0 Ciliary rootlet component, centrosome cohesion Eryth_link_C PF16915.5 CAM37601.1 - 0.42 10.6 38.3 2.2e+02 1.8 0.1 12.9 3 2 18 21 21 21 0 Annelid erythrocruorin linker subunit C-terminus Filament PF00038.21 CAM37601.1 - 0.78 9.3 232.9 2.6 7.6 14.1 14.5 1 1 7 11 11 11 0 Intermediate filament protein Enolase_C PF00113.22 CAM37602.1 - 1.5e-81 273.9 0.0 2e-81 273.5 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 CAM37602.1 - 5.3e-58 194.9 0.1 8.5e-58 194.2 0.1 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain Enolase_C PF00113.22 CAM37603.1 - 1.8e-129 431.2 0.0 2.4e-129 430.8 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 CAM37603.1 - 3.5e-58 195.4 0.1 6.4e-58 194.6 0.1 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 CAM37603.1 - 5.1e-08 32.8 0.0 8.6e-08 32.0 0.0 1.4 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 CAM37603.1 - 0.00016 20.9 0.1 0.00034 19.9 0.1 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus FYVE PF01363.21 CAM37604.1 - 4.8e-16 58.6 20.9 1.3e-15 57.2 14.5 3.2 2 1 0 2 2 2 1 FYVE zinc finger Ras PF00071.22 CAM37604.1 - 2.5e-10 40.2 0.0 4.1e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAM37604.1 - 8.7e-08 32.4 0.0 1.6e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase F-box-like PF12937.7 CAM37604.1 - 0.00057 19.7 0.5 0.0017 18.2 0.1 2.1 2 0 0 2 2 2 1 F-box-like IBR PF01485.21 CAM37604.1 - 0.019 15.2 6.2 0.019 15.2 6.2 2.1 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Zf_RING PF16744.5 CAM37604.1 - 0.022 14.8 6.1 0.076 13.1 1.8 2.6 2 0 0 2 2 2 0 KIAA1045 RING finger AAA_7 PF12775.7 CAM37604.1 - 0.093 12.2 0.0 0.48 9.9 0.0 2.1 3 0 0 3 3 3 0 P-loop containing dynein motor region PAP_central PF04928.17 CAM37605.1 - 7.1e-55 185.7 0.0 1.2e-54 184.9 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 CAM37605.1 - 1.2e-34 119.5 0.0 3.4e-34 117.9 0.0 1.7 1 1 1 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 CAM37605.1 - 1e-05 25.7 0.0 2.3e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain DNA_pol_B_palm PF14792.6 CAM37605.1 - 0.019 15.2 0.0 0.046 13.9 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase beta palm Carb_kinase PF01256.17 CAM37606.1 - 7.8e-51 172.9 5.3 1.4e-50 172.0 5.3 1.4 1 0 0 1 1 1 1 Carbohydrate kinase YjeF_N PF03853.15 CAM37606.1 - 1.2e-44 152.2 0.0 3.1e-44 150.9 0.0 1.7 1 0 0 1 1 1 1 YjeF-related protein N-terminus DFP PF04127.15 CAM37606.1 - 0.078 12.8 0.2 0.35 10.7 0.0 2.0 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein PSS PF03034.15 CAM37607.1 - 2.6e-98 329.1 12.2 3.9e-98 328.6 12.2 1.3 1 0 0 1 1 1 1 Phosphatidyl serine synthase DUF4131 PF13567.6 CAM37607.1 - 1.9 8.1 16.0 1.3 8.6 3.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) NIF PF03031.18 CAM37608.1 - 3.2e-14 53.0 0.0 9.9e-07 28.7 0.0 2.1 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase DUF4795 PF16043.5 CAM37609.2 - 0.0006 19.5 34.8 0.0029 17.3 1.1 6.7 4 2 2 6 6 6 2 Domain of unknown function (DUF4795) BLOC1_2 PF10046.9 CAM37609.2 - 0.2 12.0 24.6 0.25 11.7 2.2 4.8 6 0 0 6 6 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 CAM37609.2 - 0.22 10.4 31.7 0.24 10.2 0.2 4.7 2 1 4 6 6 6 0 Spc7 kinetochore protein Lge1 PF11488.8 CAM37609.2 - 0.32 11.2 2.0 18 5.6 0.1 3.2 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 NBP1 PF08537.10 CAM37609.2 - 0.44 9.9 6.3 0.4 10.1 0.3 2.7 2 0 0 2 2 2 0 Fungal Nap binding protein NBP1 SPACA9 PF15120.6 CAM37609.2 - 0.99 9.2 6.8 0.7 9.6 0.0 3.5 3 1 2 5 5 5 0 Sperm acrosome-associated protein 9 PspB PF06667.12 CAM37609.2 - 1.3 9.1 3.3 12 6.1 0.2 3.3 3 0 0 3 3 2 0 Phage shock protein B Occludin_ELL PF07303.13 CAM37609.2 - 3.4 8.5 14.1 44 4.9 0.3 5.7 5 2 1 6 6 6 0 Occludin homology domain SesA PF17107.5 CAM37609.2 - 7.2 6.8 8.3 19 5.5 0.9 4.1 2 1 1 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases SKA2 PF16740.5 CAM37609.2 - 7.5 6.4 23.7 3.8 7.3 0.4 6.4 5 1 3 8 8 8 0 Spindle and kinetochore-associated protein 2 V_ATPase_I PF01496.19 CAM37609.2 - 8.8 4.1 13.0 2.8 5.7 1.1 3.0 3 1 0 3 3 3 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 CAM37609.2 - 9.7 5.4 39.4 1.1 8.5 6.3 4.1 2 1 2 4 4 4 0 Domain of unknown function (DUF4407) HTH_37 PF13744.6 CAM37611.1 - 0.11 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain NRD1_2 PF01995.16 CAM37611.1 - 0.24 10.6 0.0 0.43 9.8 0.0 1.3 1 0 0 1 1 1 0 NrpR regulatory domains NRD1 and 2 Pax7 PF12360.8 CAM37612.1 - 0.047 13.9 0.2 0.11 12.7 0.2 1.6 1 0 0 1 1 1 0 Paired box protein 7 Ribosomal_S27 PF01599.19 CAM37614.1 - 1e-22 80.0 4.2 1.9e-22 79.2 4.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.23 CAM37614.1 - 7.1e-10 38.5 0.4 6.3e-09 35.5 0.0 2.4 2 1 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 CAM37614.1 - 5.9e-05 22.8 0.4 0.00072 19.3 0.0 2.4 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.21 CAM37614.1 - 0.0069 16.6 0.7 0.011 15.9 0.7 1.4 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain F420_oxidored PF03807.17 CAM37615.1 - 1.4e-06 28.8 0.0 4.3e-06 27.2 0.0 1.9 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.17 CAM37615.1 - 0.087 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase TSNAXIP1_N PF15739.5 CAM37616.1 - 0.022 15.2 0.9 0.022 15.2 0.9 3.3 4 0 0 4 4 4 0 Translin-associated factor X-interacting N-terminus DUF919 PF06034.11 CAM37616.1 - 7 6.6 6.3 11 5.9 0.0 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Pkinase PF00069.25 CAM37617.1 - 4.2e-64 216.5 0.0 2.2e-56 191.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM37617.1 - 1.1e-35 123.2 0.0 3.1e-33 115.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAM37617.1 - 0.00013 20.9 0.0 0.00013 20.9 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CAM37617.1 - 0.027 14.4 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 CAM37617.1 - 0.095 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CAM37617.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like SHMT PF00464.19 CAM37619.1 - 1.6e-172 573.6 0.0 1.9e-172 573.4 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DnaJ PF00226.31 CAM37620.1 - 4.9e-20 71.4 3.0 1.2e-19 70.2 3.0 1.7 1 0 0 1 1 1 1 DnaJ domain TPR_19 PF14559.6 CAM37620.1 - 8.7e-15 55.0 18.2 0.0007 20.1 0.3 6.4 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 CAM37620.1 - 0.00011 22.7 15.2 0.03 14.9 0.3 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 CAM37620.1 - 0.00028 21.5 23.8 1.3 10.1 0.0 7.8 5 3 5 10 10 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 CAM37620.1 - 0.00042 20.3 2.5 0.33 11.3 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 CAM37620.1 - 0.00073 19.6 13.9 0.23 11.6 0.9 4.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CAM37620.1 - 0.0038 17.5 10.9 0.57 10.5 1.3 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 CAM37620.1 - 0.021 15.4 11.5 1.7e+02 3.2 0.0 7.8 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_2 PF07719.17 CAM37620.1 - 0.03 14.4 12.4 13 6.2 0.0 6.9 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 CAM37620.1 - 0.036 13.8 0.0 11 5.8 0.0 2.7 2 0 0 2 2 2 0 TPR repeat TPR_1 PF00515.28 CAM37620.1 - 0.073 12.9 6.3 21 5.1 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF884 PF05959.11 CAM37620.1 - 0.12 12.1 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF884) Alkyl_sulf_dimr PF14863.6 CAM37620.1 - 0.15 12.5 1.9 4 7.9 0.1 3.3 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation DUF4726 PF15855.5 CAM37620.1 - 0.18 12.1 0.9 6.6 7.0 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4726) TPR_17 PF13431.6 CAM37620.1 - 0.3 11.6 2.3 14 6.3 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat HemY_N PF07219.13 CAM37620.1 - 0.41 10.9 3.9 3.6 7.8 0.1 3.5 3 0 0 3 3 3 0 HemY protein N-terminus TPR_7 PF13176.6 CAM37620.1 - 1.1 9.4 5.1 9 6.6 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat FA_desaturase PF00487.24 CAM37621.1 - 3.6e-33 115.5 11.4 3.6e-33 115.5 11.4 1.7 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 CAM37621.1 - 0.0074 16.4 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MMR_HSR1 PF01926.23 CAM37622.1 - 0.045 13.8 0.0 0.49 10.5 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase NAD_binding_5 PF07994.12 CAM37624.1 - 8e-136 452.6 0.0 9.2e-136 452.4 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 CAM37624.1 - 4.7e-44 149.1 0.0 8.1e-44 148.3 0.0 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase tRNA-synt_1b PF00579.25 CAM37626.1 - 9e-54 182.8 0.0 1.1e-48 166.0 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class I (W and Y) EMP24_GP25L PF01105.24 CAM37628.1 - 9.4e-21 74.6 0.0 1.1e-20 74.4 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2309 PF10070.9 CAM37629.1 - 0.059 11.7 0.1 0.069 11.5 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) Pkinase PF00069.25 CAM37630.1 - 1.6e-64 217.8 0.0 2e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM37630.1 - 4.9e-44 150.5 0.0 7.2e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM37630.1 - 1.1e-06 28.1 0.1 2.4e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CAM37630.1 - 0.00016 20.6 0.0 0.00031 19.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase WD40 PF00400.32 CAM37632.1 - 0.00025 21.8 21.0 18 6.4 0.0 9.4 10 0 0 10 10 10 2 WD domain, G-beta repeat IFT46_B_C PF12317.8 CAM37632.1 - 0.13 12.0 3.2 0.14 11.9 0.0 2.4 3 0 0 3 3 3 0 Intraflagellar transport complex B protein 46 C terminal PBP1_TM PF14812.6 CAM37632.1 - 0.53 10.7 7.3 2.4 8.6 7.3 2.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FlaC_arch PF05377.11 CAM37632.1 - 5.1 7.6 6.2 24 5.4 0.6 3.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) C2 PF00168.30 CAM37633.1 - 1e-06 28.9 0.0 0.072 13.4 0.0 2.5 2 0 0 2 2 2 2 C2 domain Rubredoxin PF00301.20 CAM37633.1 - 0.087 12.9 0.2 0.21 11.6 0.2 1.6 1 0 0 1 1 1 0 Rubredoxin Vac14_Fig4_bd PF11916.8 CAM37634.1 - 3.6e-46 157.1 4.6 3.6e-46 157.1 4.6 1.7 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 CAM37634.1 - 1.2e-09 38.6 0.1 1.6e-07 31.8 0.0 3.1 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 CAM37634.1 - 0.013 15.7 0.0 0.013 15.7 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat Cnd1 PF12717.7 CAM37634.1 - 0.021 14.8 0.0 0.21 11.6 0.0 2.4 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CAM37634.1 - 1.6 9.2 7.5 6.1 7.3 0.0 4.7 5 0 0 5 5 5 0 HEAT repeats MPC PF03650.13 CAM37635.1 - 2.7e-14 53.3 0.1 3.2e-14 53.0 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers GST_N_3 PF13417.6 CAM37637.1 - 1.1e-07 32.2 0.0 1.9e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 CAM37637.1 - 1.9e-07 31.2 0.4 4.3e-07 30.0 0.4 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_N_2 PF13409.6 CAM37637.1 - 0.083 13.2 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Syja_N PF02383.18 CAM37638.1 - 3.2e-26 92.4 0.0 4.8e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain ASF1_hist_chap PF04729.13 CAM37640.1 - 2.5e-25 89.2 0.0 3e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone Ribosomal_L27A PF00828.19 CAM37641.2 - 1.1e-07 32.6 0.0 1.7e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A ADK PF00406.22 CAM37642.1 - 1.5e-10 41.3 0.0 3.1e-05 24.1 0.0 2.2 1 1 1 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 CAM37642.1 - 2.2e-08 34.6 0.1 5e-05 23.7 0.3 2.3 1 1 1 2 2 2 2 AAA domain AAA_18 PF13238.6 CAM37642.1 - 3.6e-07 30.8 0.0 1.9e-05 25.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CAM37642.1 - 0.00012 22.3 0.0 0.00019 21.7 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 CAM37642.1 - 0.00021 21.5 0.2 0.0027 17.9 0.1 2.1 1 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CAM37642.1 - 0.00052 19.3 0.2 0.0077 15.5 0.0 2.3 3 0 0 3 3 3 1 Zeta toxin DUF5582 PF17819.1 CAM37642.1 - 0.001 19.5 0.3 0.0026 18.2 0.1 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF5582) cobW PF02492.19 CAM37642.1 - 0.0011 18.6 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 CAM37642.1 - 0.0012 18.5 0.1 0.002 17.8 0.1 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 CAM37642.1 - 0.0014 19.0 0.1 0.0025 18.2 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain TsaE PF02367.17 CAM37642.1 - 0.0019 18.2 0.0 0.003 17.5 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 CAM37642.1 - 0.0024 18.3 0.0 0.0039 17.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 CAM37642.1 - 0.0052 16.4 0.0 0.013 15.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CAM37642.1 - 0.0052 16.8 0.1 0.014 15.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 CAM37642.1 - 0.0064 16.4 0.1 0.011 15.6 0.1 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 CAM37642.1 - 0.0067 16.7 0.3 0.032 14.5 0.1 2.1 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 CAM37642.1 - 0.0069 16.4 0.0 0.0083 16.2 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain RuvB_N PF05496.12 CAM37642.1 - 0.0088 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain T2SSE PF00437.20 CAM37642.1 - 0.0092 15.1 0.1 0.03 13.4 0.1 1.8 1 1 1 2 2 2 1 Type II/IV secretion system protein NTPase_1 PF03266.15 CAM37642.1 - 0.01 15.7 0.1 0.017 15.0 0.1 1.3 1 0 0 1 1 1 0 NTPase dNK PF01712.19 CAM37642.1 - 0.024 14.5 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Deoxynucleoside kinase ResIII PF04851.15 CAM37642.1 - 0.024 14.7 0.0 0.042 13.8 0.0 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Thymidylate_kin PF02223.17 CAM37642.1 - 0.03 14.0 0.0 5.6 6.6 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase AAA_14 PF13173.6 CAM37642.1 - 0.032 14.2 0.3 0.15 12.1 0.0 2.1 3 1 0 4 4 2 0 AAA domain AAA_30 PF13604.6 CAM37642.1 - 0.035 13.8 0.1 0.058 13.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 CAM37642.1 - 0.038 13.4 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit APS_kinase PF01583.20 CAM37642.1 - 0.051 13.5 0.0 0.086 12.7 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_29 PF13555.6 CAM37642.1 - 0.052 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PhoH PF02562.16 CAM37642.1 - 0.056 12.9 0.1 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein Hydin_ADK PF17213.3 CAM37642.1 - 0.064 13.5 1.7 0.068 13.4 0.7 1.5 2 0 0 2 2 1 0 Hydin Adenylate kinase-like domain CoaE PF01121.20 CAM37642.1 - 0.095 12.4 0.8 0.18 11.5 0.1 1.8 2 0 0 2 2 2 0 Dephospho-CoA kinase Mg_chelatase PF01078.21 CAM37642.1 - 0.099 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 CAM37642.1 - 0.099 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 CAM37642.1 - 0.1 12.3 0.2 0.2 11.4 0.2 1.5 1 0 0 1 1 1 0 Cytidylate kinase IstB_IS21 PF01695.17 CAM37642.1 - 0.11 12.3 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 CAM37642.1 - 0.12 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.22 CAM37642.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain PduV-EutP PF10662.9 CAM37642.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 CAM37642.1 - 0.16 12.5 0.0 0.28 11.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter PrmA PF06325.13 CAM37643.1 - 2.2e-05 24.0 0.3 3.3e-05 23.4 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CAM37643.1 - 0.0083 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 CAM37643.1 - 0.021 15.5 0.1 0.06 14.1 0.1 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 CAM37643.1 - 0.025 13.5 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Met_10 PF02475.16 CAM37643.1 - 0.07 12.9 0.0 0.098 12.4 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_11 PF08241.12 CAM37643.1 - 0.085 13.5 0.0 0.2 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 CAM37643.1 - 0.088 12.1 0.1 0.17 11.1 0.1 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.15 CAM37643.1 - 0.092 12.4 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PCMT PF01135.19 CAM37643.1 - 0.12 12.1 0.1 0.17 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 2OG-FeII_Oxy_3 PF13640.6 CAM37644.1 - 5.5e-12 46.4 0.0 1.4e-11 45.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 CAM37644.1 - 6.8e-05 23.2 0.0 0.00012 22.4 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Pox_C4_C10 PF03336.13 CAM37644.1 - 0.0049 16.0 0.0 0.2 10.7 0.0 2.3 1 1 0 1 1 1 1 Poxvirus C4/C10 protein TPR_6 PF13174.6 CAM37644.1 - 0.044 14.4 0.2 0.13 13.0 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DEAD PF00270.29 CAM37645.1 - 6.2e-18 65.2 0.0 2.3e-15 56.8 0.0 2.3 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CAM37645.1 - 9.1e-14 51.7 0.0 6e-13 49.1 0.0 2.4 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAM37645.1 - 0.019 14.9 0.0 0.042 13.8 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF4770 PF15994.5 CAM37645.1 - 0.093 13.0 0.2 1.7 8.8 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4770) AAA PF00004.29 CAM37646.2 - 7.1e-45 152.7 0.0 2.3e-44 151.0 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CAM37646.2 - 5.7e-07 29.4 0.0 2.1e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CAM37646.2 - 8.5e-05 23.0 1.2 0.0064 16.9 0.0 3.6 3 1 0 4 4 3 1 AAA ATPase domain AAA_2 PF07724.14 CAM37646.2 - 0.00014 22.0 0.0 0.00037 20.6 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) Vps4_C PF09336.10 CAM37646.2 - 0.00031 20.7 0.0 0.00083 19.3 0.0 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 CAM37646.2 - 0.00047 19.9 0.7 0.22 11.3 0.0 3.1 3 0 0 3 3 3 1 AAA+ lid domain AAA_33 PF13671.6 CAM37646.2 - 0.0015 18.7 0.0 0.0039 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CAM37646.2 - 0.0022 18.0 0.0 0.0087 16.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 CAM37646.2 - 0.003 17.3 0.0 0.014 15.2 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein RNA_helicase PF00910.22 CAM37646.2 - 0.0051 17.2 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 CAM37646.2 - 0.0051 16.8 0.0 0.0098 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.17 CAM37646.2 - 0.0097 15.0 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 TIP49 PF06068.13 CAM37646.2 - 0.016 14.5 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_22 PF13401.6 CAM37646.2 - 0.016 15.4 0.2 0.12 12.7 0.1 2.5 3 1 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 CAM37646.2 - 0.018 14.5 0.1 0.042 13.2 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 CAM37646.2 - 0.018 14.6 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 CAM37646.2 - 0.042 13.8 0.0 0.08 12.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 CAM37646.2 - 0.052 13.8 0.0 0.16 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 CAM37646.2 - 0.056 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 KaiC PhoH PF02562.16 CAM37646.2 - 0.056 12.9 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 CAM37646.2 - 0.079 13.5 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 CAM37646.2 - 0.13 12.8 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 CAM37646.2 - 0.15 12.5 0.0 0.62 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Kelch_4 PF13418.6 CAM37648.1 - 3.9e-35 119.6 0.1 2.6e-12 46.5 0.0 6.5 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 CAM37648.1 - 2.4e-25 88.0 2.2 0.001 19.0 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 CAM37648.1 - 8.3e-25 86.5 2.9 0.00015 21.9 0.0 6.9 6 1 0 6 6 6 6 Galactose oxidase, central domain DUF4110 PF13422.6 CAM37648.1 - 1e-21 76.8 7.8 1e-21 76.8 7.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.6 CAM37648.1 - 1.4e-19 69.6 6.0 4.7e-05 23.5 0.0 6.6 5 1 1 6 6 6 6 Kelch motif Kelch_1 PF01344.25 CAM37648.1 - 2.1e-19 68.8 0.5 0.0011 18.5 0.0 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 CAM37648.1 - 5.1e-12 45.3 6.2 0.084 12.9 0.1 6.5 6 0 0 6 6 6 3 Kelch motif Cytochrom_NNT PF03264.14 CAM37648.1 - 0.014 15.1 1.5 0.032 14.0 1.5 1.6 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region Mobilization_B PF17511.2 CAM37649.1 - 0.13 12.6 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Mobilization protein B MORN PF02493.20 CAM37650.1 - 4.2e-13 48.3 9.5 1.6e-07 30.8 0.9 4.7 4 0 0 4 4 4 2 MORN repeat Peptidase_U4 PF03419.13 CAM37650.1 - 0.038 13.3 0.3 0.038 13.3 0.3 2.5 3 0 0 3 3 3 0 Sporulation factor SpoIIGA Ribosomal_S12 PF17487.2 CAM37650.1 - 0.78 10.5 8.4 0.073 13.8 2.5 2.5 2 0 0 2 2 2 0 Ribosomal protein S12 APH PF01636.23 CAM37651.1 - 1.1e-12 48.3 0.0 3.2e-12 46.9 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family eIF-1a PF01176.19 CAM37654.1 - 4.2e-13 48.9 0.3 6.2e-13 48.3 0.3 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Ribosomal_L17 PF01196.19 CAM37656.1 - 6.3e-12 46.2 0.0 9.4e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L17 Las1 PF04031.13 CAM37659.1 - 4.2e-33 114.6 0.1 7e-33 113.9 0.1 1.4 1 0 0 1 1 1 1 Las1-like DUF5337 PF17272.2 CAM37659.1 - 0.021 14.7 0.3 0.043 13.6 0.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5337) Mito_carr PF00153.27 CAM37660.1 - 3.6e-61 203.1 1.1 8.7e-20 70.5 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CAM37660.1 - 0.21 10.7 0.3 49 2.9 0.0 3.3 3 1 1 4 4 4 0 Gammaproteobacterial serine protease Mito_carr PF00153.27 CAM37661.1 - 2.1e-52 175.0 6.3 1.1e-17 63.7 0.4 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein AIM3 PF17096.5 CAM37661.1 - 0.032 15.2 0.4 0.054 14.4 0.4 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 MAP65_ASE1 PF03999.12 CAM37661.1 - 0.045 12.5 0.1 0.058 12.1 0.1 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DSPc PF00782.20 CAM37663.1 - 6.7e-08 32.4 0.0 9.4e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CAM37663.1 - 0.00016 21.3 0.0 0.00023 20.8 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase RuBisCO_large PF00016.20 CAM37663.1 - 0.11 11.7 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Radical_SAM_C PF16199.5 CAM37664.1 - 3.8e-20 71.7 0.3 1.2e-19 70.1 0.2 1.9 2 0 0 2 2 2 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 CAM37664.1 - 3e-15 57.0 0.0 1.3e-14 54.9 0.0 2.1 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 CAM37664.1 - 8.3e-08 32.5 0.1 2.3e-07 31.0 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CAM37664.1 - 3.8e-05 23.6 0.1 7.5e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CAM37664.1 - 0.012 16.0 0.1 0.027 14.9 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DSPc PF00782.20 CAM37665.1 - 6.9e-08 32.4 0.0 8.3e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CAM37665.1 - 3.1e-05 23.7 0.0 3.7e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Hydrolase_4 PF12146.8 CAM37666.2 - 8.7e-12 44.8 0.5 9.8e-07 28.3 0.3 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Ank_2 PF12796.7 CAM37666.2 - 8.1e-09 36.0 0.0 7.1e-08 32.9 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Abhydrolase_1 PF00561.20 CAM37666.2 - 1e-08 35.2 0.3 1.9e-05 24.4 0.2 2.8 3 1 1 4 4 4 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CAM37666.2 - 5.6e-08 33.7 0.1 1.2e-07 32.5 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ank_4 PF13637.6 CAM37666.2 - 1.4e-06 28.7 0.1 6.8e-05 23.3 0.1 3.3 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CAM37666.2 - 2e-06 27.7 0.1 5.3e-05 23.3 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Peptidase_S9 PF00326.21 CAM37666.2 - 6.4e-06 25.8 0.1 0.029 13.8 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Ank PF00023.30 CAM37666.2 - 1.7e-05 25.1 0.0 0.0001 22.5 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 CAM37666.2 - 5.2e-05 23.5 0.1 0.0015 18.8 0.0 2.8 2 1 0 2 2 2 1 Ankyrin repeats (many copies) AXE1 PF05448.12 CAM37666.2 - 0.00012 20.9 0.7 0.018 13.8 0.7 2.2 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 CAM37666.2 - 0.0026 17.4 0.0 0.14 11.7 0.0 2.3 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Bac_rhamnosid_C PF17390.2 CAM37666.2 - 0.065 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase C-terminal domain Say1_Mug180 PF10340.9 CAM37666.2 - 0.13 11.1 0.0 5 5.9 0.0 2.1 2 0 0 2 2 2 0 Steryl acetyl hydrolase Nas2_N PF18265.1 CAM37668.1 - 5.5e-21 74.3 0.0 1.1e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 CAM37668.1 - 6.2e-05 22.8 0.1 0.00014 21.6 0.1 1.7 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 CAM37668.1 - 0.006 16.9 0.0 0.012 15.9 0.0 1.5 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 CAM37668.1 - 0.013 15.8 0.0 0.037 14.3 0.0 1.8 1 0 0 1 1 1 0 PDZ domain COMMD1_N PF17221.3 CAM37668.1 - 0.021 15.1 2.2 0.021 15.1 2.2 1.7 2 0 0 2 2 2 0 COMMD1 N-terminal domain DUF4407 PF14362.6 CAM37668.1 - 0.027 13.8 6.0 0.036 13.4 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AP-5_subunit_s1 PF15001.6 CAM37668.1 - 0.07 13.1 0.4 0.1 12.6 0.4 1.3 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 Pkinase PF00069.25 CAM37669.1 - 3e-63 213.7 0.0 3.8e-63 213.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM37669.1 - 1e-46 159.4 0.0 1.3e-46 159.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAM37669.1 - 0.00037 19.4 0.0 0.00056 18.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CAM37669.1 - 0.081 12.2 0.0 0.25 10.6 0.0 1.7 2 0 0 2 2 2 0 Kinase-like HTH_32 PF13565.6 CAM37670.1 - 1.5 9.5 6.6 16 6.2 0.1 4.4 4 0 0 4 4 4 0 Homeodomain-like domain Met_10 PF02475.16 CAM37671.1 - 3.3e-47 160.8 0.1 5.9e-35 120.8 0.0 2.2 2 0 0 2 2 2 2 Met-10+ like-protein PrmA PF06325.13 CAM37671.1 - 0.0042 16.5 0.0 0.0071 15.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TRM PF02005.16 CAM37671.1 - 0.047 12.8 0.0 0.088 12.0 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase FHA PF00498.26 CAM37672.1 - 3.6e-14 52.8 0.0 7.7e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 FHA domain 2OG-FeII_Oxy_2 PF13532.6 CAM37675.2 - 4.1e-62 209.9 0.2 5.6e-62 209.4 0.2 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TTL PF03133.15 CAM37678.1 - 3.1e-78 262.9 0.0 1.6e-77 260.5 0.0 2.0 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 CAM37678.1 - 6e-06 25.7 0.0 0.018 14.3 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 CAM37678.1 - 1.7e-05 24.2 0.0 0.024 13.9 0.0 2.4 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 CAM37678.1 - 0.054 13.5 0.0 2 8.4 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp domain XRN_N PF03159.18 CAM37679.2 - 7e-21 74.8 8.7 5.1e-20 71.9 0.0 4.0 4 1 0 4 4 4 2 XRN 5'-3' exonuclease N-terminus NAM-associated PF14303.6 CAM37681.1 - 5.6 7.7 9.0 0.23 12.1 2.9 1.8 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Pyridoxal_deC PF00282.19 CAM37682.1 - 9.9e-17 60.7 0.7 4.7e-12 45.3 0.0 2.5 3 0 0 3 3 3 2 Pyridoxal-dependent decarboxylase conserved domain RVT_1 PF00078.27 CAM37685.1 - 1.4e-05 24.7 0.0 2.3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DZR PF12773.7 CAM37685.1 - 0.019 15.0 4.4 0.22 11.6 0.2 2.7 2 0 0 2 2 2 0 Double zinc ribbon FYVE PF01363.21 CAM37685.1 - 3 8.0 6.1 0.91 9.7 0.0 3.0 4 0 0 4 4 4 0 FYVE zinc finger RVT_1 PF00078.27 CAM37686.1 - 9.7e-22 77.6 0.0 2.4e-21 76.3 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L21e PF01157.18 CAM37687.1 - 1.4e-40 137.2 3.1 2.1e-40 136.7 3.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e Fucokinase PF07959.12 CAM37689.1 - 1.9e-14 53.4 0.0 3.5e-13 49.3 0.0 2.4 1 1 0 1 1 1 1 L-fucokinase GHMP_kinases_N PF00288.26 CAM37689.1 - 3e-06 27.4 1.8 0.00024 21.3 0.0 2.9 2 0 0 2 2 2 2 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CAM37689.1 - 0.00025 21.3 0.0 0.00083 19.7 0.0 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal CcmE PF03100.15 CAM37690.1 - 0.6 10.1 1.8 0.73 9.8 0.0 1.9 2 1 0 2 2 2 0 CcmE Amastin PF07344.11 CAM37691.2 - 4e-06 26.7 9.6 6.8e-06 26.0 9.5 1.5 1 1 0 1 1 1 1 Amastin surface glycoprotein LssY_C PF14067.6 CAM37691.2 - 0.22 11.0 0.0 0.98 8.9 0.0 1.8 2 0 0 2 2 2 0 LssY C-terminus FtsL PF04999.13 CAM37691.2 - 1.2 9.2 3.7 2.8 8.0 0.1 2.5 3 0 0 3 3 3 0 Cell division protein FtsL Macoilin PF09726.9 CAM37692.1 - 0.25 9.9 9.7 0.41 9.1 9.7 1.4 1 0 0 1 1 1 0 Macoilin family DUF3510 PF12022.8 CAM37693.1 - 0.023 15.1 0.0 0.045 14.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) OTCace_N PF02729.21 CAM37695.1 - 7.5e-39 133.1 0.3 1.3e-38 132.3 0.3 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 CAM37695.1 - 1.3e-31 109.8 0.1 6.3e-31 107.6 0.0 1.8 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OMPdecase PF00215.24 CAM37696.1 - 1.8e-36 125.8 0.0 2.6e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.27 CAM37696.1 - 1e-18 67.4 0.2 3.2e-18 65.7 0.2 1.8 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CAM37696.1 - 0.00031 20.3 0.0 0.00066 19.2 0.0 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 CAM37696.1 - 0.0008 19.0 0.0 0.0018 17.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase DUF3933 PF13069.6 CAM37696.1 - 0.021 14.6 0.1 12 5.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3933) Phage_Coat_Gp8 PF05371.12 CAM37696.1 - 2.3 8.1 4.9 0.58 10.0 1.1 2.1 2 0 0 2 2 2 0 Phage major coat protein, Gp8 AAA_18 PF13238.6 CAM37697.1 - 0.00054 20.5 0.0 0.0025 18.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain PRK PF00485.18 CAM37697.1 - 0.0097 15.7 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 CAM37697.1 - 0.02 15.0 0.0 0.043 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CAM37697.1 - 0.12 12.7 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Cytidylate_kin PF02224.18 CAM37697.1 - 0.16 11.7 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase Amidohydro_1 PF01979.20 CAM37698.1 - 2.3e-09 37.0 1.6 3.1e-09 36.6 1.6 1.2 1 0 0 1 1 1 1 Amidohydrolase family Usp PF00582.26 CAM37698.1 - 0.13 12.8 0.4 0.35 11.4 0.4 1.7 1 0 0 1 1 1 0 Universal stress protein family CPSase_L_D2 PF02786.17 CAM37699.1 - 1.4e-101 338.4 0.3 4.4e-77 258.3 0.2 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 CAM37699.1 - 1.2e-45 154.5 0.0 3.3e-45 153.1 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 CAM37699.1 - 3.2e-40 138.0 0.0 8.3e-40 136.6 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 CAM37699.1 - 1.3e-29 103.0 0.1 3.9e-29 101.5 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 CAM37699.1 - 2.8e-20 72.6 0.1 4.3e-11 42.7 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Arginosuc_synth PF00764.19 CAM37699.1 - 1.5e-13 50.8 0.0 3.4e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Arginosuccinate synthase Dala_Dala_lig_C PF07478.13 CAM37699.1 - 3.7e-12 46.2 0.5 2.5e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 CAM37699.1 - 3e-10 39.9 0.0 0.0001 22.1 0.0 2.7 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.22 CAM37699.1 - 2.7e-07 30.7 0.0 1.4e-06 28.3 0.0 2.4 2 0 0 2 2 1 1 MGS-like domain Peptidase_C26 PF07722.13 CAM37699.1 - 3.5e-07 30.2 0.3 1.9e-05 24.5 0.3 2.6 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.14 CAM37699.1 - 8.9e-05 22.6 0.2 0.0036 17.4 0.0 2.7 2 1 0 2 2 2 1 ATP-grasp domain DJ-1_PfpI PF01965.24 CAM37699.1 - 0.00083 19.2 0.1 0.01 15.6 0.0 2.6 3 0 0 3 3 3 1 DJ-1/PfpI family TrkA_N PF02254.18 CAM37699.1 - 0.0085 16.3 0.0 0.063 13.5 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain TP6A_N PF04406.14 CAM37701.1 - 1.8e-10 40.7 0.6 3.6e-10 39.7 0.6 1.6 1 0 0 1 1 1 1 Type IIB DNA topoisomerase RRM_1 PF00076.22 CAM37702.1 - 1.8e-12 46.9 0.0 3.2e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.21 CAM37702.1 - 1.2e-06 28.9 0.0 0.051 13.8 0.0 2.3 2 0 0 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-rbx1 PF12678.7 CAM37703.1 - 3.2e-17 62.5 12.3 4.4e-17 62.1 12.3 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CAM37703.1 - 1.1e-14 54.2 7.0 1.5e-14 53.8 7.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 CAM37703.1 - 2.4e-10 40.6 13.8 5.5e-09 36.2 10.8 2.2 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 CAM37703.1 - 1.1e-06 28.3 12.3 2.3e-05 24.2 9.1 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CAM37703.1 - 1.2e-06 28.3 13.0 5e-06 26.4 8.8 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CAM37703.1 - 1.5e-05 24.9 12.2 0.00022 21.2 10.0 2.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CAM37703.1 - 2.5e-05 24.1 13.0 0.00015 21.5 7.6 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 CAM37703.1 - 3.1e-05 23.8 5.4 3.1e-05 23.8 5.4 1.7 1 1 1 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.6 CAM37703.1 - 0.0001 22.1 16.0 0.00097 18.9 11.4 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CAM37703.1 - 0.00073 19.1 9.7 0.00073 19.1 9.7 1.8 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 CAM37703.1 - 0.00078 19.3 12.5 0.0041 17.0 12.5 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 CAM37703.1 - 0.0023 18.1 13.1 0.032 14.4 3.8 3.2 1 1 2 3 3 3 1 FANCL C-terminal domain Rtf2 PF04641.12 CAM37703.1 - 0.0062 15.9 0.2 0.0062 15.9 0.2 1.9 1 1 1 2 2 2 1 Rtf2 RING-finger zf-RING_4 PF14570.6 CAM37703.1 - 0.096 12.5 9.6 2.6 7.9 6.9 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 CAM37703.1 - 0.31 10.8 14.1 8 6.3 14.1 2.4 1 1 0 1 1 1 0 RING-like zinc finger zf-Di19 PF05605.12 CAM37703.1 - 0.42 10.9 9.7 1.1 9.6 4.6 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.14 CAM37703.1 - 0.56 10.1 4.2 13 5.7 0.3 2.7 2 1 0 2 2 2 0 Rad50 zinc hook motif DUF1272 PF06906.11 CAM37703.1 - 0.75 9.9 11.0 56 3.9 11.0 2.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) zf-Nse PF11789.8 CAM37703.1 - 0.8 9.6 7.4 3.8 7.4 7.4 2.1 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit tRNA-synt_1g PF09334.11 CAM37703.1 - 0.93 8.2 3.1 1.7 7.3 0.5 1.9 1 1 1 2 2 2 0 tRNA synthetases class I (M) zf-C3HC4_4 PF15227.6 CAM37703.1 - 1.4 9.1 13.3 34 4.7 2.0 3.3 1 1 2 3 3 3 0 zinc finger of C3HC4-type, RING TerY_C PF15616.6 CAM37703.1 - 3.9 7.6 10.0 64 3.7 10.0 2.0 1 1 0 1 1 1 0 TerY-C metal binding domain Zn-C2H2_12 PF18112.1 CAM37703.1 - 4.5 7.8 10.4 18 5.9 0.1 3.4 3 1 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C3H2C3 PF17122.5 CAM37703.1 - 6.6 6.9 15.3 0.96 9.5 8.9 2.3 1 1 0 2 2 2 0 Zinc-finger HMMR_N PF15905.5 CAM37704.1 - 0.00095 18.7 29.8 0.00095 18.7 29.8 4.4 2 2 2 4 4 4 1 Hyaluronan mediated motility receptor N-terminal DUF1738 PF08401.11 CAM37705.2 - 0.083 13.0 0.0 2.9 8.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1738) Exo_endo_phos PF03372.23 CAM37706.1 - 3.8e-16 59.3 0.0 6.1e-16 58.6 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family eIF2A PF08662.11 CAM37707.1 - 1.7e-38 132.4 0.0 2.8e-30 105.7 0.0 3.2 3 0 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A LysM PF01476.20 CAM37708.1 - 8.9e-06 25.7 0.0 0.1 12.7 0.0 2.3 2 0 0 2 2 2 2 LysM domain Spc29 PF17082.5 CAM37709.1 - 0.0058 16.5 0.1 0.015 15.2 0.1 1.6 1 0 0 1 1 1 1 Spindle Pole Component 29 LRR_6 PF13516.6 CAM37710.1 - 1.9e-10 39.9 11.0 0.83 9.9 0.1 6.7 6 0 0 6 6 6 5 Leucine Rich repeat LRR_4 PF12799.7 CAM37710.1 - 1.7e-06 28.2 3.2 0.031 14.7 0.0 4.2 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CAM37710.1 - 9.8e-05 22.4 2.1 16 6.5 0.0 5.6 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_8 PF13855.6 CAM37710.1 - 0.12 12.1 11.2 2.9 7.7 0.4 4.5 3 1 1 4 4 4 0 Leucine rich repeat UCH PF00443.29 CAM37711.1 - 8.6e-35 120.5 0.0 1.6e-34 119.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CAM37711.1 - 1.2e-17 64.5 0.0 1.6e-15 57.5 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase TetR_C_27 PF17935.1 CAM37711.1 - 0.017 15.2 0.2 6.1 6.9 0.0 2.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain GDH_N PF12466.8 CAM37711.1 - 1.5 9.1 4.4 5.7 7.2 0.0 4.0 4 0 0 4 4 4 0 Glutamate dehydrogenase N terminal TAL_FSA PF00923.19 CAM37714.1 - 3.8e-96 321.8 0.0 4.4e-96 321.6 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase FixO PF02433.15 CAM37714.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO SH3BGR PF04908.15 CAM37715.1 - 0.012 15.7 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein VPS13 PF16908.5 CAM37716.2 - 1.3e-29 103.7 0.1 3.7e-29 102.2 0.1 1.8 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 CAM37716.2 - 8.7e-21 74.5 0.2 4.9e-14 52.5 0.0 2.4 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 CAM37716.2 - 7.7e-18 64.7 0.2 2.8e-10 40.3 0.1 2.7 2 0 0 2 2 2 2 N-terminal region of Chorein or VPS13 VPS13_mid_rpt PF16910.5 CAM37716.2 - 8.2e-12 45.1 0.0 1.2e-08 34.7 0.0 3.0 3 0 0 3 3 3 2 Repeating coiled region of VPS13 SHR-BD PF06650.12 CAM37716.2 - 0.0064 15.9 0.0 14 4.9 0.0 3.7 4 0 0 4 4 4 1 SHR-binding domain of vacuolar-sorting associated protein 13 Roughex PF06020.11 CAM37716.2 - 0.027 13.6 0.3 0.068 12.3 0.3 1.6 1 0 0 1 1 1 0 Drosophila roughex protein TFIIS_C PF01096.18 CAM37716.2 - 0.2 11.6 2.9 0.47 10.3 1.7 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) PTH2 PF01981.16 CAM37717.1 - 0.00082 19.7 0.2 4.2 7.7 0.0 4.5 4 1 0 4 4 4 1 Peptidyl-tRNA hydrolase PTH2 SPG4 PF17325.2 CAM37717.1 - 0.0012 19.9 17.0 4.6 8.4 0.8 6.2 6 0 0 6 6 6 1 Stationary phase protein 4 DZR PF12773.7 CAM37717.1 - 0.056 13.5 0.2 0.14 12.2 0.2 1.6 1 0 0 1 1 1 0 Double zinc ribbon RVT_1 PF00078.27 CAM37718.2 - 1.1e-21 77.4 0.0 2.8e-21 76.0 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) FYVE PF01363.21 CAM37718.2 - 0.23 11.6 1.0 0.59 10.3 0.0 2.0 2 0 0 2 2 2 0 FYVE zinc finger Glyco_hydro_18 PF00704.28 CAM37719.1 - 8.2e-49 167.0 0.0 9.9e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Mem_trans PF03547.18 CAM37720.1 - 5.9e-08 31.5 20.1 1.4e-07 30.3 0.1 3.3 3 1 0 3 3 3 2 Membrane transport protein DUF1427 PF07235.11 CAM37720.1 - 0.036 14.0 1.9 2.2 8.3 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1427) BILBO1_N PF18281.1 CAM37722.1 - 5.7e-05 23.5 0.3 0.0092 16.4 0.1 2.4 2 0 0 2 2 2 2 BILBO1 N-terminal domain EF-hand_1 PF00036.32 CAM37722.1 - 0.022 14.3 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 EF hand Fe-S_biosyn PF01521.20 CAM37723.1 - 6e-08 32.9 0.1 4.8e-07 30.0 0.1 2.3 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis ALF PF03752.13 CAM37724.1 - 0.48 10.4 2.5 7.8 6.6 0.9 2.6 2 0 0 2 2 2 0 Short repeats of unknown function JAB PF01398.21 CAM37725.1 - 3.5e-21 75.4 0.0 5.7e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 CAM37725.1 - 0.0032 17.2 0.0 0.0088 15.8 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain REV PF00424.18 CAM37726.1 - 0.029 14.4 0.0 0.15 12.1 0.0 2.0 1 1 1 2 2 2 0 REV protein (anti-repression trans-activator protein) Pkinase PF00069.25 CAM37727.1 - 4.1e-29 101.8 0.0 8.4e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM37727.1 - 6.6e-22 78.0 0.0 1.8e-21 76.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAM37727.1 - 6.2e-05 22.0 0.0 0.00011 21.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase zf-ACC PF17848.1 CAM37727.1 - 0.058 13.5 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain zf-C2H2_4 PF13894.6 CAM37727.1 - 0.36 11.8 2.0 1.1 10.3 2.0 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger Nop52 PF05997.12 CAM37728.1 - 3.1e-32 112.1 1.0 1.1e-26 94.0 0.4 3.4 3 0 0 3 3 3 3 Nucleolar protein,Nop52 EF-hand_1 PF00036.32 CAM37731.1 - 3.8e-12 44.8 0.4 8.6e-06 24.9 0.0 3.2 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 CAM37731.1 - 1.5e-10 40.1 0.1 0.0005 19.8 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CAM37731.1 - 7.1e-10 39.2 1.4 5.1e-08 33.3 0.1 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CAM37731.1 - 4e-07 29.8 1.0 0.00015 21.6 0.0 2.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CAM37731.1 - 0.0031 16.9 1.3 0.082 12.4 0.2 2.9 2 1 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.9 CAM37731.1 - 0.022 15.1 0.0 0.043 14.1 0.0 1.5 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 CAM37731.1 - 0.061 14.2 0.0 0.12 13.2 0.0 1.5 2 0 0 2 2 2 0 EF-hand domain EF-hand_6 PF13405.6 CAM37732.1 - 2.4e-15 55.1 0.4 0.00085 19.1 0.0 3.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 CAM37732.1 - 5.7e-15 53.7 0.9 1.4e-05 24.2 0.0 4.0 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 CAM37732.1 - 4.5e-13 49.5 0.5 9.6e-08 32.4 0.1 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 CAM37732.1 - 4.4e-09 36.1 2.5 0.00028 20.6 0.0 3.6 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 CAM37732.1 - 1.2e-06 27.7 1.9 0.15 11.6 0.3 3.6 3 1 0 3 3 3 2 EF hand EF-hand_10 PF14788.6 CAM37732.1 - 0.0058 16.5 0.1 0.52 10.2 0.0 3.0 3 0 0 3 3 3 1 EF hand SPARC_Ca_bdg PF10591.9 CAM37732.1 - 0.014 15.8 0.2 0.11 12.8 0.0 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 CAM37732.1 - 0.062 14.2 0.1 0.25 12.2 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain Snf7 PF03357.21 CAM37733.1 - 1e-23 83.8 12.7 1e-23 83.8 12.7 1.3 1 1 0 1 1 1 1 Snf7 SSXT PF05030.12 CAM37733.1 - 0.8 9.4 5.8 2.8 7.6 0.4 2.5 2 0 0 2 2 2 0 SSXT protein (N-terminal region) DUF3801 PF12687.7 CAM37733.1 - 1.8 8.6 9.1 0.63 10.1 6.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3801) V_ATPase_I PF01496.19 CAM37733.1 - 2.2 6.1 5.8 1.6 6.6 4.5 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Dynein_light PF01221.18 CAM37734.1 - 8.8e-25 86.8 0.6 1e-24 86.6 0.6 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Glycos_transf_1 PF00534.20 CAM37735.2 - 1.7e-27 96.1 0.0 2.8e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CAM37735.2 - 8.5e-19 68.3 0.0 1.8e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CAM37735.2 - 0.001 19.1 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 CAM37735.2 - 0.0012 19.2 0.0 0.0029 18.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 HMG_box_2 PF09011.10 CAM37735.2 - 0.12 13.0 0.0 3.8 8.2 0.0 2.4 2 0 0 2 2 2 0 HMG-box domain Methyltransf_23 PF13489.6 CAM37736.1 - 5.3e-15 55.7 0.0 5.9e-14 52.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAM37736.1 - 1.5e-14 54.4 0.0 1.5e-13 51.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 CAM37736.1 - 3e-11 43.1 0.0 2.1e-10 40.3 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 CAM37736.1 - 1.5e-10 41.6 0.0 1.1e-07 32.4 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 CAM37736.1 - 9.8e-07 28.7 0.0 3.8e-05 23.5 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAM37736.1 - 3e-06 27.9 0.0 0.0011 19.7 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain ZapB PF06005.12 CAM37738.1 - 0.017 15.5 0.8 0.017 15.5 0.8 13.4 4 3 3 8 8 8 0 Cell division protein ZapB HALZ PF02183.18 CAM37738.1 - 0.048 13.9 0.8 0.048 13.9 0.8 6.9 9 0 0 9 9 9 0 Homeobox associated leucine zipper DUF2325 PF10087.9 CAM37738.1 - 0.37 10.9 2.6 16 5.7 0.0 4.7 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2325) DUF4041 PF13250.6 CAM37738.1 - 0.4 10.6 4.4 0.72 9.8 0.1 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4041) Hemagglutinin PF00509.18 CAM37738.1 - 1.5 7.1 7.7 0.11 10.9 2.0 1.9 2 0 0 2 2 2 0 Haemagglutinin Pkinase PF00069.25 CAM37739.1 - 2.1e-58 197.7 0.0 5e-34 117.9 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM37739.1 - 6e-29 101.1 0.0 2e-19 69.9 0.0 3.2 3 0 0 3 3 3 2 Protein tyrosine kinase PNP_UDP_1 PF01048.20 CAM37739.1 - 0.026 13.8 0.0 0.05 12.9 0.0 1.4 1 0 0 1 1 1 0 Phosphorylase superfamily Kdo PF06293.14 CAM37739.1 - 0.04 13.3 0.0 0.081 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Stealth_CR3 PF17102.5 CAM37740.1 - 8.6e-11 41.6 0.3 8.6e-11 41.6 0.3 2.1 2 0 0 2 2 2 1 Stealth protein CR3, conserved region 3 Stealth_CR2 PF11380.8 CAM37740.1 - 9.6e-08 32.2 0.1 2.2e-07 31.0 0.0 1.6 2 0 0 2 2 2 1 Stealth protein CR2, conserved region 2 Stealth_CR2 PF11380.8 CAM37741.1 - 1.2e-16 60.8 0.0 2.5e-08 34.0 0.0 2.5 2 0 0 2 2 2 2 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 CAM37741.1 - 2.9e-12 46.3 3.4 6.8e-12 45.1 3.4 1.7 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Stealth_CR3 PF17102.5 CAM37742.1 - 1.5e-10 40.8 0.3 1.5e-10 40.8 0.3 2.0 2 0 0 2 2 2 1 Stealth protein CR3, conserved region 3 Stealth_CR2 PF11380.8 CAM37742.1 - 1.8e-07 31.3 0.0 3.9e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR2 PF11380.8 CAM37743.1 - 3.5e-16 59.3 0.0 2.6e-08 34.0 0.0 2.5 2 0 0 2 2 2 2 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 CAM37743.1 - 6.8e-11 41.9 0.3 2.2e-10 40.3 0.3 2.0 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Stealth_CR3 PF17102.5 CAM37744.1 - 4.6e-07 29.6 4.1 9.4e-07 28.6 4.1 1.6 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Stealth_CR2 PF11380.8 CAM37746.1 - 8e-17 61.4 0.0 2.1e-08 34.3 0.0 2.6 2 0 0 2 2 2 2 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 CAM37746.1 - 3.2e-07 30.1 4.2 1.4e-06 28.1 4.2 2.3 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 DUF2182 PF09948.9 CAM37746.1 - 0.053 13.4 0.6 0.09 12.6 0.6 1.3 1 0 0 1 1 1 0 Predicted metal-binding integral membrane protein (DUF2182) Stealth_CR2 PF11380.8 CAM37747.1 - 2.7e-17 62.9 0.0 5.7e-09 36.1 0.0 2.6 2 0 0 2 2 2 2 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 CAM37747.1 - 3.9e-12 45.9 0.7 8.8e-12 44.7 0.7 1.7 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Virul_fac_BrkB PF03631.15 CAM37747.1 - 0.013 15.1 1.3 0.024 14.3 1.3 1.3 1 0 0 1 1 1 0 Virulence factor BrkB Ufm1 PF03671.14 CAM37748.1 - 5.7e-34 116.1 0.1 6.7e-34 115.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein GRA6 PF05084.13 CAM37749.1 - 0.034 14.1 3.2 0.069 13.1 3.2 1.4 1 0 0 1 1 1 0 Granule antigen protein (GRA6) Polyketide_cyc PF03364.20 CAM37753.1 - 1.2e-11 44.9 0.1 8.7e-11 42.1 0.1 2.1 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport tRNA_bind PF01588.20 CAM37755.1 - 1e-22 80.0 0.0 1.8e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain WW PF00397.26 CAM37756.1 - 1.2e-44 150.1 32.1 2.7e-14 52.9 1.6 5.4 5 0 0 5 5 5 5 WW domain Mcp5_PH PF12814.7 CAM37756.1 - 0.18 11.9 0.6 0.72 10.0 0.1 2.2 3 0 0 3 3 3 0 Meiotic cell cortex C-terminal pleckstrin homology Tfb5 PF06331.12 CAM37757.1 - 4.8e-05 23.2 0.0 0.00013 21.9 0.0 1.6 1 1 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Ribosomal_L39 PF00832.20 CAM37760.1 - 3.4e-18 65.0 15.4 3.8e-18 64.8 15.4 1.0 1 0 0 1 1 1 1 Ribosomal L39 protein Adap_comp_sub PF00928.21 CAM37761.1 - 2.6e-13 50.0 0.0 3.9e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CAM37761.1 - 0.00078 19.4 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AAA_25 PF13481.6 CAM37761.1 - 0.087 12.4 0.0 0.2 11.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain RSN1_7TM PF02714.15 CAM37762.2 - 1.8e-24 86.6 9.8 3.2e-24 85.7 9.8 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 CAM37762.2 - 0.019 15.2 0.0 0.038 14.2 0.0 1.4 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Methyltransf_9 PF08003.11 CAM37762.2 - 0.095 11.6 0.1 0.17 10.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Pro_isomerase PF00160.21 CAM37763.1 - 9.8e-31 107.2 0.0 1.4e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD dsrm PF00035.26 CAM37764.1 - 0.0039 17.9 0.1 4.3 8.1 0.0 3.9 4 0 0 4 4 4 1 Double-stranded RNA binding motif Cullin PF00888.22 CAM37765.2 - 1.1e-38 133.3 0.0 6.1e-33 114.3 0.0 4.1 4 1 0 4 4 4 2 Cullin family Cullin_Nedd8 PF10557.9 CAM37765.2 - 2.8e-15 56.1 0.0 5.1e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Cullin protein neddylation domain LSM PF01423.22 CAM37769.1 - 0.00016 21.3 0.1 0.001 18.7 0.1 2.0 1 1 0 1 1 1 1 LSM domain Raf1_N PF18578.1 CAM37772.1 - 0.088 13.3 0.5 0.12 12.9 0.5 1.3 1 1 0 1 1 1 0 Rubisco accumulation factor 1 alpha helical domain DAGK_acc PF00609.19 CAM37773.2 - 1.1e-21 77.9 0.0 5.7e-21 75.5 0.0 2.1 1 1 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 CAM37773.2 - 4.1e-07 29.7 0.0 1.5e-06 27.8 0.0 1.9 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain Cytochrom_C PF00034.21 CAM37775.1 - 6.2e-12 46.5 0.0 7.7e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 CAM37775.1 - 6.6e-05 23.1 1.0 0.0005 20.3 1.0 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 CAM37776.1 - 3e-11 44.3 0.0 3.7e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 CAM37776.1 - 5.5e-05 23.4 0.7 0.00042 20.6 0.7 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III LRR_4 PF12799.7 CAM37777.2 - 9.5e-25 86.3 26.8 0.015 15.7 0.2 12.5 8 3 5 15 15 15 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM37777.2 - 1.6e-14 53.4 30.1 3.5e-05 23.5 0.2 9.5 7 3 2 10 10 10 6 Leucine rich repeat LRR_6 PF13516.6 CAM37777.2 - 1.1e-06 28.1 26.1 0.82 9.9 0.1 12.1 13 0 0 13 13 13 3 Leucine Rich repeat LRR_9 PF14580.6 CAM37777.2 - 1.2e-05 24.9 12.2 0.3 10.6 0.3 5.9 5 2 0 6 6 6 3 Leucine-rich repeat LRR_2 PF07723.13 CAM37777.2 - 0.12 13.0 1.9 2.7 8.8 0.4 3.6 3 0 0 3 3 3 0 Leucine Rich Repeat RNA_pol_Rpb1_5 PF04998.17 CAM37779.1 - 6.9e-58 196.2 0.0 2.9e-57 194.1 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CAM37779.1 - 3.3e-49 167.3 0.0 5.9e-49 166.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 CAM37779.1 - 1.6e-28 99.6 0.0 3.5e-28 98.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CAM37779.1 - 3.7e-15 55.8 0.6 1e-14 54.4 0.6 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.12 CAM37779.1 - 0.072 12.4 0.5 0.21 10.9 0.0 2.0 3 0 0 3 3 3 0 RNA polymerase Rpb1, domain 1 Nop14 PF04147.12 CAM37779.1 - 9 4.4 6.9 15 3.7 6.9 1.2 1 0 0 1 1 1 0 Nop14-like family Amidase PF01425.21 CAM37780.1 - 1.1e-59 202.6 0.0 1.2e-58 199.1 0.0 2.0 1 1 0 1 1 1 1 Amidase UPF0524 PF15823.5 CAM37780.1 - 0.0047 16.4 0.2 0.0091 15.4 0.2 1.4 1 0 0 1 1 1 1 UPF0524 of C3orf70 LSM PF01423.22 CAM37781.1 - 3.2e-05 23.5 0.0 4.3e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 LSM domain Arf PF00025.21 CAM37782.1 - 1.2e-48 164.8 0.0 1.4e-48 164.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CAM37782.1 - 2e-10 40.9 0.0 2.8e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CAM37782.1 - 3.8e-10 39.5 0.0 4.9e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CAM37782.1 - 9e-10 38.4 0.5 1.3e-08 34.6 0.2 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Ras PF00071.22 CAM37782.1 - 3.3e-09 36.5 0.0 3.8e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CAM37782.1 - 8.9e-09 35.0 2.1 7e-05 22.1 0.3 2.7 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 CAM37782.1 - 4.2e-08 33.3 0.0 5.7e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CAM37782.1 - 6.5e-07 28.9 0.1 8.2e-07 28.6 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 CAM37782.1 - 0.00011 22.5 0.1 0.0062 16.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CAM37782.1 - 0.00027 20.9 0.0 0.28 11.1 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 CAM37782.1 - 0.00036 20.1 0.1 0.00065 19.3 0.1 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B cobW PF02492.19 CAM37782.1 - 0.012 15.2 0.0 1.8 8.2 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 CAM37782.1 - 0.018 15.6 0.0 0.03 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 CAM37782.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Septin OTU PF02338.19 CAM37783.1 - 4.5e-14 53.0 0.0 8.6e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease LcrV PF04792.12 CAM37783.1 - 0.13 11.5 0.2 0.22 10.8 0.2 1.2 1 0 0 1 1 1 0 V antigen (LcrV) protein EMG1 PF03587.14 CAM37784.1 - 7.6e-58 195.4 0.0 1.3e-57 194.6 0.0 1.4 1 1 0 1 1 1 1 EMG1/NEP1 methyltransferase HTH_18 PF12833.7 CAM37784.1 - 0.02 15.2 0.2 8.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain TRAPP PF04051.16 CAM37785.1 - 1.4e-22 80.0 0.0 1.8e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component CLN3 PF02487.17 CAM37786.1 - 0.84 8.6 2.8 1.2 8.1 2.8 1.2 1 0 0 1 1 1 0 CLN3 protein Flagellar_rod PF05149.12 CAM37787.1 - 1e-105 353.3 27.1 1e-105 353.3 27.1 2.0 2 0 0 2 2 2 1 Paraflagellar rod protein ING PF12998.7 CAM37787.1 - 2.7 8.7 17.6 0.047 14.3 1.9 3.6 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding UPF0225 PF17775.1 CAM37787.1 - 4.1 8.3 8.8 7.5 7.4 1.3 3.4 2 1 0 2 2 2 0 UPF0225 domain Flagellar_rod PF05149.12 CAM37788.1 - 1.6e-106 356.0 27.1 2e-106 355.6 27.1 1.1 1 0 0 1 1 1 1 Paraflagellar rod protein ING PF12998.7 CAM37788.1 - 0.38 11.4 15.1 0.037 14.6 2.9 2.7 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding PAPS_reduct PF01507.19 CAM37788.1 - 1 9.4 11.6 1.3 9.1 3.1 2.6 2 1 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family DUF1664 PF07889.12 CAM37788.1 - 1.3 9.0 9.2 0.76 9.8 0.3 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) UPF0225 PF17775.1 CAM37788.1 - 2.4 9.1 10.3 3.5 8.5 1.5 3.2 2 1 0 2 2 2 0 UPF0225 domain Allexi_40kDa PF05549.11 CAM37788.1 - 9.9 5.6 7.6 6.3 6.2 0.7 2.4 1 1 1 2 2 2 0 Allexivirus 40kDa protein Laminin_I PF06008.14 CAM37790.1 - 2.1e-18 67.0 137.7 0.00094 19.0 16.0 7.9 1 1 5 7 7 7 7 Laminin Domain I ApoB100_C PF12491.8 CAM37790.1 - 6.7e-17 61.2 65.7 5.9 6.9 0.1 17.4 2 2 21 24 24 24 13 Apolipoprotein B100 C terminal Spc7 PF08317.11 CAM37790.1 - 9.3e-15 54.3 153.0 0.0046 15.9 28.8 6.4 2 1 4 6 6 6 5 Spc7 kinetochore protein DUF3552 PF12072.8 CAM37790.1 - 9.6e-10 38.2 141.3 0.94 8.9 12.2 10.0 2 1 7 9 9 9 3 Domain of unknown function (DUF3552) Herpes_BLLF1 PF05109.13 CAM37790.1 - 1.2e-08 33.5 39.5 0.0073 14.4 8.3 4.4 1 1 4 5 5 5 5 Herpes virus major outer envelope glycoprotein (BLLF1) COG2 PF06148.11 CAM37790.1 - 1.5e-08 34.8 90.2 0.85 9.7 5.5 10.6 2 1 10 12 12 12 10 COG (conserved oligomeric Golgi) complex component, COG2 IFT57 PF10498.9 CAM37790.1 - 3.4e-08 32.9 121.3 0.005 15.9 19.1 7.0 1 1 7 8 8 8 7 Intra-flagellar transport protein 57 V-SNARE_C PF12352.8 CAM37790.1 - 3.7e-08 33.5 59.9 1.4 9.3 0.9 11.4 3 1 13 16 16 15 11 Snare region anchored in the vesicle membrane C-terminus Laminin_II PF06009.12 CAM37790.1 - 6.6e-08 32.7 123.7 1.6 8.7 10.1 10.2 2 1 12 14 14 14 8 Laminin Domain II KxDL PF10241.9 CAM37790.1 - 2.5e-07 30.9 103.6 0.68 10.2 6.0 10.8 2 1 10 13 13 13 8 Uncharacterized conserved protein Tropomyosin PF00261.20 CAM37790.1 - 8.9e-06 25.2 164.8 0.01 15.2 40.5 5.1 2 1 3 5 5 5 4 Tropomyosin MscS_porin PF12795.7 CAM37790.1 - 0.0011 18.5 179.3 7.7 6.0 25.5 8.5 1 1 3 4 4 2 0 Mechanosensitive ion channel porin domain ATG16 PF08614.11 CAM37790.1 - 0.0031 17.8 175.4 25 5.0 46.2 6.2 2 1 3 5 5 4 0 Autophagy protein 16 (ATG16) ApoO PF09769.9 CAM37790.1 - 0.0081 16.1 72.9 11 6.0 0.4 11.8 2 1 11 13 13 13 0 Apolipoprotein O TMF_TATA_bd PF12325.8 CAM37790.1 - 0.0088 16.3 147.4 4.1 7.7 13.8 9.4 2 1 9 11 11 11 3 TATA element modulatory factor 1 TATA binding Atg14 PF10186.9 CAM37790.1 - 0.012 14.8 104.8 5.4 6.0 21.1 5.4 1 1 4 5 5 5 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 CAM37790.1 - 0.16 11.5 106.0 14 5.1 16.4 6.0 1 1 2 3 3 2 0 Exonuclease VII, large subunit TMF_DNA_bd PF12329.8 CAM37790.1 - 0.21 11.6 164.8 2.6 8.1 7.9 13.0 2 1 12 16 16 16 0 TATA element modulatory factor 1 DNA binding Tropomyosin_1 PF12718.7 CAM37790.1 - 0.46 10.6 185.2 0.89 9.7 35.2 7.9 2 1 6 8 8 8 0 Tropomyosin like EzrA PF06160.12 CAM37790.1 - 1.1 7.3 114.6 0.35 9.0 74.8 3.9 2 1 2 4 4 4 0 Septation ring formation regulator, EzrA Myosin_tail_1 PF01576.19 CAM37790.1 - 2.4 5.9 141.5 0.014 13.3 56.1 4.0 1 1 2 4 4 4 0 Myosin tail DUF4200 PF13863.6 CAM37790.1 - 2.7 8.4 129.2 3.9 7.9 20.8 9.4 2 1 8 10 10 9 0 Domain of unknown function (DUF4200) KASH_CCD PF14662.6 CAM37790.1 - 4 7.2 144.5 3.8 7.3 31.0 6.8 2 1 5 7 7 7 0 Coiled-coil region of CCDC155 or KASH ApoLp-III PF07464.11 CAM37790.1 - 5.5 7.1 137.2 7.1 6.7 17.3 8.7 2 1 7 9 9 9 0 Apolipophorin-III precursor (apoLp-III) MAD PF05557.13 CAM37790.1 - 6 5.1 135.9 2.6 6.3 31.6 4.8 2 1 3 5 5 5 0 Mitotic checkpoint protein WXG100 PF06013.12 CAM37790.1 - 7 7.0 123.2 0.29 11.4 11.4 14.7 2 1 10 12 12 11 0 Proteins of 100 residues with WXG HMMR_N PF15905.5 CAM37790.1 - 8.8 5.7 140.8 0.33 10.4 30.4 4.6 1 1 3 4 4 3 0 Hyaluronan mediated motility receptor N-terminal Laminin_I PF06008.14 CAM37791.2 - 5.4e-41 141.0 292.2 4.1e-05 23.4 14.7 16.4 1 1 12 15 15 15 15 Laminin Domain I ApoB100_C PF12491.8 CAM37791.2 - 3.4e-33 113.4 164.1 2.5 8.2 0.1 37.6 2 2 58 63 63 63 4 Apolipoprotein B100 C terminal Spc7 PF08317.11 CAM37791.2 - 4.9e-31 107.8 308.8 0.0022 17.0 27.9 10.8 1 1 11 12 12 12 12 Spc7 kinetochore protein DUF3552 PF12072.8 CAM37791.2 - 2.2e-20 72.9 274.3 1.1 8.6 8.2 19.3 1 1 17 18 18 17 8 Domain of unknown function (DUF3552) COG2 PF06148.11 CAM37791.2 - 2.3e-19 69.8 178.0 0.19 11.8 3.5 20.0 1 1 24 25 25 25 21 COG (conserved oligomeric Golgi) complex component, COG2 Herpes_BLLF1 PF05109.13 CAM37791.2 - 2.2e-17 62.4 98.6 0.012 13.6 5.5 10.6 1 1 10 11 11 11 10 Herpes virus major outer envelope glycoprotein (BLLF1) KxDL PF10241.9 CAM37791.2 - 7.3e-17 61.4 214.6 0.36 11.1 4.6 18.8 1 1 24 25 25 25 20 Uncharacterized conserved protein Laminin_II PF06009.12 CAM37791.2 - 2.3e-16 60.1 252.9 0.23 11.5 10.1 18.2 1 1 14 17 17 17 13 Laminin Domain II V-SNARE_C PF12352.8 CAM37791.2 - 1.1e-15 57.7 135.7 1.6 9.1 1.4 22.6 1 1 29 30 30 30 13 Snare region anchored in the vesicle membrane C-terminus Tropomyosin PF00261.20 CAM37791.2 - 8.7e-14 51.5 335.2 0.06 12.7 51.2 8.8 1 1 6 8 8 8 8 Tropomyosin IFT57 PF10498.9 CAM37791.2 - 6.7e-13 48.3 249.8 0.27 10.2 17.7 12.3 1 1 8 10 10 10 9 Intra-flagellar transport protein 57 ATG16 PF08614.11 CAM37791.2 - 4.1e-09 37.0 358.2 2.5 8.3 36.8 10.9 1 1 8 9 9 7 2 Autophagy protein 16 (ATG16) MAD PF05557.13 CAM37791.2 - 2.9e-06 26.0 270.1 0.071 11.5 47.4 7.2 1 1 6 7 7 7 4 Mitotic checkpoint protein Exonuc_VII_L PF02601.15 CAM37791.2 - 6.8e-06 25.9 209.4 3.9 6.9 17.7 10.2 1 1 1 2 2 1 1 Exonuclease VII, large subunit TMF_TATA_bd PF12325.8 CAM37791.2 - 7.4e-06 26.2 300.5 1.8 8.8 9.7 17.6 1 1 16 18 18 18 3 TATA element modulatory factor 1 TATA binding MscS_porin PF12795.7 CAM37791.2 - 2.9e-05 23.7 368.4 25 4.3 14.4 16.0 1 1 12 13 13 11 0 Mechanosensitive ion channel porin domain Atg14 PF10186.9 CAM37791.2 - 0.00062 19.0 222.7 0.81 8.7 10.3 10.4 1 1 10 11 11 10 2 Vacuolar sorting 38 and autophagy-related subunit 14 EzrA PF06160.12 CAM37791.2 - 0.00068 17.9 235.1 0.11 10.7 76.1 4.1 1 1 1 3 3 3 3 Septation ring formation regulator, EzrA Tropomyosin_1 PF12718.7 CAM37791.2 - 0.0011 19.1 381.0 5.6 7.1 34.7 13.6 1 1 16 17 17 17 1 Tropomyosin like KASH_CCD PF14662.6 CAM37791.2 - 0.16 11.8 293.7 17 5.2 32.3 10.5 1 1 8 10 10 10 0 Coiled-coil region of CCDC155 or KASH ApoO PF09769.9 CAM37791.2 - 0.16 11.9 154.4 27 4.7 0.6 23.7 1 1 37 38 38 38 0 Apolipoprotein O HrpB7 PF09486.10 CAM37791.2 - 0.53 10.7 238.4 0.66 10.3 17.1 13.3 1 1 14 15 15 13 0 Bacterial type III secretion protein (HrpB7) DUF4200 PF13863.6 CAM37791.2 - 5.8 7.3 259.6 53 4.2 18.9 15.6 1 1 17 18 18 15 0 Domain of unknown function (DUF4200) Kinesin PF00225.23 CAM37792.1 - 2.5e-77 260.0 0.0 5.9e-77 258.8 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CAM37792.1 - 1.3e-20 73.9 0.0 3.6e-20 72.4 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding Spc7 PF08317.11 CAM37792.1 - 0.00073 18.5 67.1 0.0047 15.8 18.1 4.6 2 1 3 5 5 5 4 Spc7 kinetochore protein ApoB100_C PF12491.8 CAM37792.1 - 0.07 13.1 3.8 18 5.4 0.1 4.0 1 1 3 4 4 4 0 Apolipoprotein B100 C terminal IFT57 PF10498.9 CAM37792.1 - 0.17 10.8 44.0 0.049 12.6 18.7 4.1 2 1 2 4 4 4 0 Intra-flagellar transport protein 57 Filament PF00038.21 CAM37792.1 - 0.74 9.3 64.6 0.0062 16.2 16.5 3.8 2 1 2 4 4 4 0 Intermediate filament protein ApoO PF09769.9 CAM37792.1 - 2.6 8.0 12.4 13 5.7 0.5 4.6 2 1 2 4 4 4 0 Apolipoprotein O aGPT-Pplase1 PF18723.1 CAM37793.1 - 0.089 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 Ribosomal_S18 PF01084.20 CAM37795.1 - 0.1 12.8 0.4 0.92 9.8 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein S18 OTT_1508_deam PF14441.6 CAM37796.1 - 0.088 12.8 0.1 9.1 6.4 0.0 2.2 2 0 0 2 2 2 0 OTT_1508-like deaminase ERO1 PF04137.15 CAM37798.1 - 5.2e-88 295.6 0.0 6.1e-88 295.4 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DNA_pol_B PF00136.21 CAM37799.1 - 2.5e-125 418.8 0.0 3.2e-125 418.4 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CAM37799.1 - 5.8e-38 130.9 0.0 1.3e-37 129.8 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.10 CAM37799.1 - 0.00035 20.4 1.4 1.1 9.0 2.4 2.4 1 1 1 2 2 2 2 DNA Polymerase alpha zinc finger DNA_pol_B_2 PF03175.13 CAM37799.1 - 0.032 13.1 0.0 0.058 12.3 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral WD40 PF00400.32 CAM37800.1 - 8.6e-15 54.9 2.9 0.008 17.0 0.1 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CAM37800.1 - 0.0036 16.3 0.3 0.067 12.1 0.0 3.2 4 0 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Peptidase_M61 PF05299.12 CAM37800.1 - 1.9 8.9 4.7 23 5.4 0.6 3.0 2 0 0 2 2 2 0 M61 glycyl aminopeptidase PPR_long PF17177.4 CAM37801.1 - 0.0044 16.4 0.3 0.3 10.4 0.0 2.6 2 1 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP RRM_1 PF00076.22 CAM37804.1 - 1e-14 54.1 0.0 1.6e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CAM37804.1 - 0.032 14.2 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif MIF4G PF02854.19 CAM37805.1 - 4.1e-23 82.1 0.4 6.1e-23 81.6 0.4 1.3 1 0 0 1 1 1 1 MIF4G domain DUF2721 PF11026.8 CAM37805.1 - 0.049 13.5 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Band_7 PF01145.25 CAM37806.1 - 2e-23 83.3 2.9 3.5e-23 82.5 2.9 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 CAM37806.1 - 6.5e-05 22.1 1.7 8.3e-05 21.8 1.7 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial ANAPC4_WD40 PF12894.7 CAM37807.1 - 0.1 12.9 0.0 1 9.7 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CAM37807.1 - 0.17 12.8 2.6 2.1 9.3 0.0 3.5 3 0 0 3 3 3 0 WD domain, G-beta repeat Nop PF01798.18 CAM37808.1 - 1.2e-11 44.5 1.7 2.7e-11 43.4 0.2 2.1 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 CAM37808.1 - 0.061 14.3 5.9 0.061 14.3 3.8 2.1 2 0 0 2 2 2 0 Prp31 C terminal domain CLU PF13236.6 CAM37810.2 - 1.1e-09 38.5 0.0 1.3e-08 35.0 0.0 2.5 1 1 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 CAM37810.2 - 8.2e-05 22.7 0.0 0.00015 21.9 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 CLU PF13236.6 CAM37811.2 - 0.0042 16.9 0.0 0.013 15.3 0.0 1.9 1 1 0 1 1 1 1 Clustered mitochondria TPR_2 PF07719.17 CAM37811.2 - 0.0045 17.0 0.9 0.42 10.8 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat eIF3_p135 PF12807.7 CAM37811.2 - 0.028 14.4 0.0 0.088 12.8 0.0 1.8 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 DUF2469 PF10611.9 CAM37812.1 - 2e-08 34.7 0.0 74 4.0 0.0 7.9 8 0 0 8 8 8 0 Protein of unknown function (DUF2469) SPG4 PF17325.2 CAM37812.1 - 0.00013 23.0 32.0 4.4 8.4 0.8 9.0 9 0 0 9 9 9 2 Stationary phase protein 4 PTH2 PF01981.16 CAM37812.1 - 0.001 19.4 0.0 1.4e+02 2.8 0.0 5.5 5 1 0 5 5 5 0 Peptidyl-tRNA hydrolase PTH2 ID PF18543.1 CAM37812.1 - 0.17 11.9 15.8 1.3e+02 2.7 0.0 7.4 8 0 0 8 8 8 0 Intracellular delivery domain HET PF06985.11 CAM37812.1 - 0.38 11.1 4.3 41 4.5 0.1 4.2 5 0 0 5 5 5 0 Heterokaryon incompatibility protein (HET) GSH-S_ATP PF02955.16 CAM37812.1 - 0.7 9.3 4.1 78 2.6 0.0 4.6 5 0 0 5 5 5 0 Prokaryotic glutathione synthetase, ATP-grasp domain RVT_1 PF00078.27 CAM37813.1 - 3.8e-17 62.6 0.0 6.1e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DZR PF12773.7 CAM37813.1 - 0.025 14.6 4.4 0.23 11.5 0.2 2.7 2 0 0 2 2 2 0 Double zinc ribbon Guanylate_cyc PF00211.20 CAM37814.1 - 1.6e-36 125.6 0.0 2.8e-36 124.8 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain FAM163 PF15069.6 CAM37814.1 - 0.093 13.2 0.0 0.83 10.1 0.0 2.5 3 0 0 3 3 3 0 FAM163 family DUF1682 PF07946.14 CAM37815.1 - 0.0046 16.2 1.5 0.0046 16.2 1.5 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1682) ANAPC3 PF12895.7 CAM37815.1 - 0.0058 16.8 0.0 0.02 15.1 0.0 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF3522 PF12036.8 CAM37816.1 - 9.2e-46 156.5 12.6 1.1e-45 156.2 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) PMP22_Claudin PF00822.20 CAM37816.1 - 0.0074 16.2 5.4 0.0074 16.2 5.4 1.6 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family DUF3784 PF12650.7 CAM37816.1 - 0.44 10.8 0.0 0.44 10.8 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3784) zf-RING_2 PF13639.6 CAM37817.1 - 3.6e-10 40.0 7.9 8.3e-10 38.9 7.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CAM37817.1 - 4.8e-08 32.9 6.5 5.6e-08 32.7 5.1 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CAM37817.1 - 1.1e-07 31.7 7.0 2.1e-07 30.7 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CAM37817.1 - 1.4e-07 31.6 9.2 1.1e-06 28.9 9.2 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CAM37817.1 - 2.5e-07 30.3 4.5 6.6e-07 29.0 4.5 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CAM37817.1 - 3.1e-07 30.1 8.3 6e-07 29.2 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CAM37817.1 - 4.4e-06 26.4 3.6 1e-05 25.3 3.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CAM37817.1 - 1.6e-05 24.8 1.6 3.2e-05 23.9 1.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 CAM37817.1 - 1.9e-05 24.5 5.1 4.1e-05 23.4 5.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CAM37817.1 - 6.6e-05 23.0 6.1 0.00016 21.8 6.1 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CAM37817.1 - 0.0057 16.5 6.9 0.34 10.8 7.9 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-Mss51 PF13824.6 CAM37817.1 - 0.038 14.1 0.8 0.16 12.1 0.4 2.3 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 CpXC PF14353.6 CAM37817.1 - 0.051 13.6 0.1 0.082 13.0 0.1 1.4 1 0 0 1 1 1 0 CpXC protein Zn_ribbon_17 PF17120.5 CAM37817.1 - 0.3 10.7 5.4 0.88 9.2 5.4 1.8 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_6 PF14835.6 CAM37817.1 - 0.3 11.0 3.0 0.29 11.0 1.4 1.9 2 1 0 2 2 1 0 zf-RING of BARD1-type protein zf-C3H2C3 PF17122.5 CAM37817.1 - 0.35 11.0 6.6 1.8 8.7 6.6 2.3 1 1 1 2 2 2 0 Zinc-finger FANCL_C PF11793.8 CAM37817.1 - 0.4 10.9 7.1 4.4 7.5 6.8 2.7 1 1 1 2 2 2 0 FANCL C-terminal domain UBZ_FAAP20 PF15750.5 CAM37817.1 - 0.55 10.2 5.0 0.84 9.6 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger DnaJ PF00226.31 CAM37818.1 - 6.6e-07 29.4 0.0 1.1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain GCR1_C PF12550.8 CAM37819.1 - 0.05 13.9 0.4 0.13 12.6 0.4 1.8 1 0 0 1 1 1 0 Transcriptional activator of glycolytic enzymes PsaN PF05479.11 CAM37819.1 - 0.13 12.5 1.1 0.21 11.7 1.1 1.4 1 1 0 1 1 1 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) Pkinase PF00069.25 CAM37820.1 - 2.5e-64 217.2 0.0 3.3e-64 216.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM37820.1 - 6.3e-38 130.5 0.0 9.9e-38 129.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM37820.1 - 9.5e-05 21.8 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like LRR_6 PF13516.6 CAM37820.1 - 0.00013 21.7 1.3 0.55 10.4 0.4 3.5 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.7 CAM37820.1 - 0.00038 20.8 0.3 0.0011 19.4 0.3 1.8 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM37820.1 - 0.0018 18.0 0.6 0.021 14.6 0.9 2.2 1 1 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.33 CAM37820.1 - 0.0027 18.0 0.5 7 7.6 0.0 3.2 2 0 0 2 2 2 2 Leucine Rich Repeat Kdo PF06293.14 CAM37820.1 - 0.0067 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CAM37820.1 - 0.0077 15.8 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 CAM37820.1 - 0.062 12.1 0.0 0.097 11.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase zf-RING_11 PF17123.5 CAM37820.1 - 0.063 13.0 0.9 0.92 9.3 0.2 2.6 2 0 0 2 2 2 0 RING-like zinc finger APH PF01636.23 CAM37820.1 - 0.098 12.6 0.0 0.61 10.0 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Arf PF00025.21 CAM37821.1 - 1.2e-67 226.7 0.1 1.5e-67 226.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CAM37821.1 - 3.9e-13 49.7 0.0 6.7e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CAM37821.1 - 1.7e-11 43.9 0.0 2e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CAM37821.1 - 1.1e-10 41.3 0.2 7.3e-08 32.0 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CAM37821.1 - 1.1e-10 41.3 0.0 1.4e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CAM37821.1 - 1.5e-08 34.3 0.0 1.8e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CAM37821.1 - 8.7e-06 25.8 0.0 1.3e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AP_endonuc_2 PF01261.24 CAM37821.1 - 0.0062 16.0 0.0 0.013 14.9 0.0 1.5 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel FeoB_N PF02421.18 CAM37821.1 - 0.0089 15.6 0.4 0.06 12.9 0.4 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 CAM37822.1 - 1.8e-51 174.5 0.0 3e-51 173.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CAM37822.1 - 2.1e-41 140.7 0.0 5.5e-41 139.4 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CAM37822.1 - 7.8e-16 58.2 1.3 1.4e-15 57.4 0.5 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CAM37822.1 - 8.7e-06 25.8 0.0 0.003 17.6 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase SRPRB PF09439.10 CAM37822.1 - 0.0018 17.8 0.1 0.009 15.5 0.1 2.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FlpD PF02662.16 CAM37822.1 - 0.0038 17.2 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 Methyl-viologen-reducing hydrogenase, delta subunit GTP_EFTU_D4 PF14578.6 CAM37822.1 - 0.0088 15.9 1.1 0.019 14.9 0.2 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Semialdhyde_dhC PF02774.18 CAM37822.1 - 0.088 12.9 0.3 0.75 9.8 0.1 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain Guanylate_cyc PF00211.20 CAM37823.1 - 3.1e-37 128.0 0.0 5.5e-37 127.1 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain FAM163 PF15069.6 CAM37823.1 - 0.16 12.4 0.0 0.61 10.5 0.0 1.9 2 0 0 2 2 2 0 FAM163 family Peripla_BP_6 PF13458.6 CAM37824.1 - 4.5e-07 29.8 0.1 2e-06 27.7 0.0 2.2 2 1 0 2 2 2 1 Periplasmic binding protein Guanylate_cyc PF00211.20 CAM37825.1 - 6.1e-37 127.0 0.0 1e-36 126.3 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 CAM37826.1 - 3.6e-36 124.5 0.0 6.2e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DLIC PF05783.11 CAM37828.1 - 0.094 11.5 0.9 0.2 10.4 0.9 1.5 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) YabA PF06156.13 CAM37828.1 - 8 7.2 12.7 58 4.4 0.1 3.2 2 1 0 2 2 2 0 Initiation control protein YabA TPR_2 PF07719.17 CAM37829.1 - 7.7e-18 63.1 2.3 0.00026 20.9 0.0 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 CAM37829.1 - 3.1e-09 37.0 1.0 0.025 14.9 0.4 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CAM37829.1 - 1e-08 34.7 7.1 0.012 15.4 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 CAM37829.1 - 8.3e-07 28.7 6.7 0.51 10.7 0.1 4.4 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 CAM37829.1 - 1.3e-06 28.6 0.2 0.071 13.8 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 CAM37829.1 - 1.1e-05 25.9 0.2 0.00014 22.3 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CAM37829.1 - 1.1e-05 25.8 0.4 8.8 7.4 0.0 4.1 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CAM37829.1 - 3.1e-05 23.7 5.8 0.013 15.4 0.1 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 CAM37829.1 - 6.1e-05 22.8 3.4 0.3 11.0 0.4 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CAM37829.1 - 0.00037 20.7 4.6 0.012 15.8 0.0 3.1 3 1 0 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 CAM37829.1 - 0.0019 18.8 0.1 1.5 9.5 0.0 3.8 2 2 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CAM37829.1 - 0.0033 17.7 0.8 15 6.2 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 CAM37829.1 - 0.013 15.1 6.9 6 6.6 0.0 4.2 3 1 0 3 3 3 0 TPR repeat TPR_21 PF09976.9 CAM37829.1 - 0.018 14.7 0.1 0.29 10.8 0.0 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain PknG_TPR PF16918.5 CAM37829.1 - 0.028 13.2 0.0 0.043 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat ROF PF07073.12 CAM37829.1 - 0.042 14.0 0.4 0.1 12.7 0.4 1.7 1 0 0 1 1 1 0 Modulator of Rho-dependent transcription termination (ROF) SLT PF01464.20 CAM37829.1 - 0.1 12.2 0.2 0.39 10.4 0.2 1.8 2 0 0 2 2 2 0 Transglycosylase SLT domain DUF896 PF05979.12 CAM37830.1 - 0.024 14.5 1.3 0.054 13.4 1.3 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) SAM_Exu PF18609.1 CAM37830.1 - 0.08 13.0 1.4 0.22 11.6 1.4 1.7 1 0 0 1 1 1 0 Exuperantia SAM-like domain M20_dimer PF07687.14 CAM37831.1 - 4.5e-11 42.6 0.0 8.5e-10 38.5 0.0 2.4 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 CAM37831.1 - 4.5e-11 42.8 0.1 7.3e-11 42.2 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 CAM37831.1 - 4.7e-05 22.6 0.1 0.00039 19.5 0.1 2.1 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.17 CAM37831.1 - 0.00011 21.9 0.0 0.00039 20.2 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 DUF5374 PF17344.2 CAM37831.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5374) FAP206 PF12018.8 CAM37832.1 - 1.9e-06 27.6 0.0 5.2e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function Kinesin PF00225.23 CAM37833.1 - 0.0016 17.4 0.0 0.0027 16.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain WD40 PF00400.32 CAM37834.1 - 6.2e-26 90.2 7.8 4.7e-07 30.4 0.1 5.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM37834.1 - 3.8e-11 43.1 0.0 0.11 12.8 0.0 4.5 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CAM37834.1 - 1.5e-06 27.4 0.1 0.0095 14.9 0.0 3.3 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 CAM37834.1 - 1.7e-05 24.7 0.2 0.61 10.1 0.0 3.9 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 CAM37834.1 - 0.001 17.8 0.3 0.89 8.1 0.0 3.2 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Frtz PF11768.8 CAM37834.1 - 0.0018 16.7 0.0 0.0046 15.3 0.0 1.5 1 1 1 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz eIF2A PF08662.11 CAM37834.1 - 0.014 15.3 0.0 0.52 10.1 0.0 2.2 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.9 CAM37834.1 - 0.14 11.9 0.1 9.1 6.1 0.0 2.8 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature RCC1 PF00415.18 CAM37835.1 - 2.6e-55 184.8 29.3 2.2e-13 50.6 0.8 8.6 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CAM37835.1 - 3.6e-25 87.2 52.4 1.1e-11 44.3 3.1 8.7 10 0 0 10 10 10 6 Regulator of chromosome condensation (RCC1) repeat BTB_2 PF02214.22 CAM37835.1 - 1.6e-06 28.4 0.0 0.08 13.3 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain PALP PF00291.25 CAM37836.1 - 2.4e-28 99.4 0.1 2.6e-28 99.3 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme 2Fe-2S_thioredx PF01257.19 CAM37838.1 - 1e-47 161.7 0.0 1.3e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF2293 PF10056.9 CAM37838.1 - 0.2 11.9 0.1 0.36 11.1 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2293) Histone_H2A_C PF16211.5 CAM37839.1 - 6.3e-12 45.0 0.5 1.5e-11 43.8 0.5 1.7 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CAM37839.1 - 3.3e-10 40.4 0.0 5.6e-10 39.7 0.0 1.4 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 zf-C3HC4_2 PF13923.6 CAM37840.1 - 9.7e-08 31.7 15.1 9.7e-08 31.7 15.1 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CAM37840.1 - 9.6e-07 28.6 17.8 9.6e-07 28.6 17.8 3.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CAM37840.1 - 4.5e-06 26.6 10.6 4.5e-06 26.6 10.6 2.6 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CAM37840.1 - 8.2e-06 25.6 14.1 8.2e-06 25.6 14.1 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CAM37840.1 - 0.00076 19.8 18.5 0.00076 19.8 18.5 3.7 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_4 PF15227.6 CAM37840.1 - 0.0012 18.9 15.9 0.0012 18.9 15.9 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CAM37840.1 - 0.0014 18.6 14.2 0.0014 18.6 14.2 3.0 3 0 0 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CAM37840.1 - 0.0027 17.5 15.6 0.011 15.6 15.6 2.1 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 LSM PF01423.22 CAM37841.1 - 1.9e-06 27.4 0.1 2.2e-05 24.1 0.1 2.1 1 1 0 1 1 1 1 LSM domain LSM14 PF12701.7 CAM37841.1 - 0.15 12.2 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Scd6-like Sm domain DUF667 PF05018.13 CAM37842.2 - 0.17 11.6 0.0 0.45 10.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF667) dsrm PF00035.26 CAM37844.2 - 0.15 12.8 0.0 10 6.9 0.0 2.7 2 0 0 2 2 2 0 Double-stranded RNA binding motif Dus PF01207.17 CAM37846.1 - 3.6e-50 170.8 0.0 6e-50 170.1 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) GLYCAM-1 PF05242.11 CAM37846.1 - 0.03 14.4 3.5 0.062 13.4 3.5 1.4 1 0 0 1 1 1 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) dCMP_cyt_deam_1 PF00383.23 CAM37847.1 - 7.2e-12 45.1 1.4 1.2e-11 44.4 1.4 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 CAM37847.1 - 1.7e-10 41.2 1.7 6e-08 33.0 1.2 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 CAM37847.1 - 0.0019 17.9 1.1 0.12 12.0 0.0 2.0 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Pheromone PF08015.11 CAM37848.1 - 0.016 16.3 1.3 0.016 16.3 1.3 4.5 5 2 1 6 6 6 0 Fungal mating-type pheromone Sec20 PF03908.13 CAM37849.1 - 7.9e-05 22.5 1.9 7.9e-05 22.5 1.9 1.9 2 0 0 2 2 2 1 Sec20 V-SNARE_C PF12352.8 CAM37849.1 - 0.01 16.1 2.5 0.026 14.8 2.5 1.8 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus Phage_holin_3_6 PF07332.11 CAM37849.1 - 0.032 14.3 0.3 0.11 12.5 0.3 1.9 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Hum_adeno_E3A PF05393.11 CAM37849.1 - 0.24 11.4 2.0 7.4 6.6 0.2 2.3 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein MLD PF11647.8 CAM37849.1 - 0.54 10.6 3.1 4.3 7.7 0.3 2.4 2 0 0 2 2 2 0 Membrane Localization Domain SNARE PF05739.19 CAM37849.1 - 0.58 10.2 6.6 0.15 12.1 2.6 2.2 2 0 0 2 2 2 0 SNARE domain Filament PF00038.21 CAM37849.1 - 6.6 6.2 12.1 0.2 11.2 2.4 2.6 3 0 0 3 3 3 0 Intermediate filament protein DUF2203 PF09969.9 CAM37849.1 - 7.2 7.4 8.0 25 5.6 2.4 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Pkinase PF00069.25 CAM37850.1 - 1.8e-61 207.8 0.0 3.3e-61 207.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM37850.1 - 2.3e-39 135.2 0.0 2.8e-38 131.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAM37850.1 - 8.5e-07 28.1 0.0 2.4e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CAM37850.1 - 4.8e-06 26.1 0.0 1.2e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CAM37850.1 - 0.0025 17.8 0.0 0.0055 16.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family ANTH PF07651.16 CAM37850.1 - 0.004 16.2 0.1 0.013 14.5 0.0 1.8 2 0 0 2 2 2 1 ANTH domain Kdo PF06293.14 CAM37850.1 - 0.0091 15.4 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RING_2 PF13639.6 CAM37851.1 - 3e-07 30.7 6.6 1.1e-06 28.9 6.6 2.1 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CAM37851.1 - 4.2e-05 23.5 4.9 4.2e-05 23.5 4.9 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CAM37851.1 - 0.0003 20.6 6.5 0.0003 20.6 6.5 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CAM37851.1 - 0.0015 18.4 8.6 0.0046 16.9 8.6 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 CAM37851.1 - 0.0021 18.3 3.7 0.01 16.1 3.7 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CAM37851.1 - 0.0021 17.8 10.3 0.052 13.4 9.1 3.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CAM37851.1 - 0.011 15.4 6.0 0.038 13.7 6.0 2.0 1 0 0 1 1 1 0 RING-like zinc finger zf-Nse PF11789.8 CAM37851.1 - 0.23 11.3 5.1 0.52 10.2 5.1 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 CAM37851.1 - 5.3 7.3 15.4 0.79 9.9 8.1 3.4 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Yop-YscD_cpl PF16697.5 CAM37852.2 - 0.12 12.7 0.0 0.37 11.1 0.0 1.8 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain DUF4106 PF13388.6 CAM37852.2 - 0.16 11.1 10.6 0.34 10.1 10.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) N6-adenineMlase PF10237.9 CAM37853.1 - 5.8e-33 114.0 1.4 9.3e-33 113.3 1.4 1.3 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Uds1 PF15456.6 CAM37853.1 - 0.042 14.0 5.4 0.12 12.5 5.4 1.8 1 0 0 1 1 1 0 Up-regulated During Septation MTS PF05175.14 CAM37853.1 - 0.1 12.1 0.0 0.35 10.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain DHHW PF14286.6 CAM37853.1 - 0.22 10.8 1.0 0.34 10.2 1.0 1.2 1 0 0 1 1 1 0 DHHW protein PKcGMP_CC PF16808.5 CAM37855.2 - 0.11 12.4 0.1 1 9.2 0.0 2.6 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Atg14 PF10186.9 CAM37855.2 - 0.17 10.9 11.0 0.029 13.5 7.0 1.7 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 BLOC1_2 PF10046.9 CAM37855.2 - 0.37 11.1 2.8 0.33 11.3 0.5 2.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cnn_1N PF07989.11 CAM37855.2 - 0.99 9.6 10.8 0.85 9.8 1.8 3.4 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 Leu_zip PF15294.6 CAM37855.2 - 2 7.9 9.3 0.14 11.7 3.9 1.8 2 0 0 2 2 2 0 Leucine zipper PMEI PF04043.15 CAM37855.2 - 3 8.2 7.3 0.79 10.1 0.9 2.7 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor GTP-bdg_M PF16360.5 CAM37855.2 - 3.3 8.4 11.3 11 6.7 1.0 4.0 3 0 0 3 3 3 0 GTP-binding GTPase Middle Region Mito_fiss_reg PF05308.11 CAM37856.2 - 0.0087 16.2 0.1 0.0087 16.2 0.1 2.8 2 1 0 2 2 2 1 Mitochondrial fission regulator SH3_16 PF18348.1 CAM37856.2 - 0.18 11.6 0.9 0.66 9.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain DnaJ PF00226.31 CAM37857.1 - 1.3e-09 38.0 0.0 2.2e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain ORF_12_N PF18042.1 CAM37857.1 - 0.12 12.8 0.0 0.28 11.6 0.0 1.6 2 0 0 2 2 2 0 ORF 12 gene product N-terminal PhzC-PhzF PF02567.16 CAM37859.1 - 7.3e-37 127.4 0.2 3.7e-25 89.0 0.0 4.3 3 1 0 3 3 3 3 Phenazine biosynthesis-like protein Sigma70_r4 PF04545.16 CAM37859.1 - 0.016 14.7 0.1 0.042 13.4 0.1 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 Autoind_bind PF03472.15 CAM37862.2 - 0.073 12.6 0.1 0.17 11.3 0.1 1.6 1 0 0 1 1 1 0 Autoinducer binding domain ERM PF00769.19 CAM37865.2 - 0.0017 18.2 5.2 0.0017 18.2 5.2 4.2 2 1 2 4 4 4 1 Ezrin/radixin/moesin family BCAS2 PF05700.11 CAM37865.2 - 0.004 16.9 7.5 0.004 16.9 7.5 4.5 2 1 1 4 4 4 1 Breast carcinoma amplified sequence 2 (BCAS2) Gon7 PF08738.10 CAM37865.2 - 1.4 9.1 4.8 1.7 8.8 0.2 2.8 2 0 0 2 2 2 0 Gon7 family DUF5082 PF16888.5 CAM37865.2 - 3.6 7.9 19.2 1.7 9.0 3.2 4.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) AAA PF00004.29 CAM37866.1 - 2.4e-09 37.7 0.0 5.5e-08 33.3 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CAM37866.1 - 1.6e-05 25.3 0.0 8.5e-05 23.0 0.0 2.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CAM37866.1 - 2.9e-05 24.3 0.0 9.9e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CAM37866.1 - 9.4e-05 22.4 0.0 0.0021 18.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 CAM37866.1 - 0.0001 22.3 0.1 0.0016 18.4 0.0 2.4 3 0 0 3 3 2 1 Rad17 P-loop domain AAA_30 PF13604.6 CAM37866.1 - 0.00011 22.0 0.3 0.0006 19.6 0.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CAM37866.1 - 0.0002 21.6 0.1 0.00064 20.0 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CAM37866.1 - 0.00036 21.1 0.0 0.0011 19.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CAM37866.1 - 0.00097 19.3 1.3 0.0022 18.2 0.0 2.4 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.12 CAM37866.1 - 0.0015 18.3 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 CAM37866.1 - 0.0033 17.3 0.0 0.0065 16.4 0.0 1.4 1 0 0 1 1 1 1 NTPase AAA_assoc_2 PF16193.5 CAM37866.1 - 0.0036 17.6 0.1 0.025 14.9 0.0 2.3 1 1 1 2 2 2 1 AAA C-terminal domain RsgA_GTPase PF03193.16 CAM37866.1 - 0.0078 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 CAM37866.1 - 0.0078 15.8 0.0 0.023 14.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CAM37866.1 - 0.014 15.8 0.1 0.058 13.7 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 CAM37866.1 - 0.025 15.0 0.0 0.083 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CAM37866.1 - 0.045 13.3 0.0 0.092 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 CAM37866.1 - 0.055 13.5 0.0 0.18 11.9 0.0 1.9 2 0 0 2 2 1 0 AAA domain dNK PF01712.19 CAM37866.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase TsaE PF02367.17 CAM37866.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 CAM37866.1 - 0.17 11.8 0.0 0.48 10.3 0.0 1.8 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 CAM37866.1 - 0.17 12.4 0.0 0.52 10.8 0.0 1.8 1 0 0 1 1 1 0 ABC transporter RRM_1 PF00076.22 CAM37867.1 - 8.1e-13 48.0 0.3 1e-08 34.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CAM37867.1 - 0.0016 18.1 0.0 0.0028 17.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 CAM37867.1 - 0.061 13.0 0.3 2.2 8.0 0.1 2.6 2 1 0 2 2 2 0 Histone lysine methyltransferase SET associated AsnC_trans_reg PF01037.21 CAM37867.1 - 0.076 13.0 0.1 4.3 7.4 0.0 2.5 2 0 0 2 2 2 0 Lrp/AsnC ligand binding domain SIP PF04954.13 CAM37867.1 - 0.14 12.7 0.0 0.36 11.4 0.0 1.7 2 0 0 2 2 2 0 Siderophore-interacting protein RRM_7 PF16367.5 CAM37867.1 - 0.14 12.3 0.1 49 4.1 0.0 3.1 2 1 1 3 3 3 0 RNA recognition motif Mito_fiss_reg PF05308.11 CAM37867.1 - 0.52 10.4 3.7 0.16 12.0 0.6 1.7 2 0 0 2 2 2 0 Mitochondrial fission regulator RCR PF12273.8 CAM37867.1 - 5.4 7.7 9.5 11 6.8 9.5 1.5 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red ELF PF03317.13 CAM37868.2 - 0.017 15.1 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 ELF protein Atg14 PF10186.9 CAM37869.2 - 0.48 9.5 14.6 1.1 8.3 5.7 2.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 LPP PF04728.13 CAM37869.2 - 0.52 10.7 3.2 35 4.9 0.1 3.5 3 0 0 3 3 3 0 Lipoprotein leucine-zipper SF-assemblin PF06705.11 CAM37869.2 - 1.7 8.0 6.3 2 7.7 0.8 2.5 2 0 0 2 2 2 0 SF-assemblin/beta giardin DUF2205 PF10224.9 CAM37869.2 - 2 8.5 5.5 5.2 7.1 0.8 3.0 2 0 0 2 2 2 0 Short coiled-coil protein Baculo_PEP_C PF04513.12 CAM37869.2 - 2 8.5 4.5 64 3.6 1.2 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Metallophos PF00149.28 CAM37870.2 - 0.0011 19.6 0.0 0.0023 18.4 0.0 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase T7SS_ESX_EspC PF10824.8 CAM37870.2 - 0.11 13.0 1.5 0.18 12.3 1.5 1.3 1 0 0 1 1 1 0 Excreted virulence factor EspC, type VII ESX diderm Cation_ATPase_C PF00689.21 CAM37872.1 - 1.7e-38 132.1 7.8 1.7e-38 132.1 7.8 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CAM37872.1 - 1.7e-31 109.1 0.6 1.7e-31 109.1 0.6 2.1 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 CAM37872.1 - 2.9e-30 104.2 0.0 6.3e-30 103.1 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CAM37872.1 - 5.9e-15 56.1 1.5 1.5e-10 41.7 0.4 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CAM37872.1 - 3.8e-11 42.5 0.0 1.5e-10 40.6 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Peptidase_M50B PF13398.6 CAM37872.1 - 0.00013 21.7 2.1 0.0005 19.8 0.6 2.4 2 0 0 2 2 2 1 Peptidase M50B-like Hydrolase_3 PF08282.12 CAM37872.1 - 0.00046 20.0 0.6 0.00093 19.0 0.6 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ACBP PF00887.19 CAM37873.1 - 1.7e-30 105.1 2.6 5.3e-16 58.6 0.0 3.4 3 0 0 3 3 3 2 Acyl CoA binding protein AP3D1 PF06375.11 CAM37873.1 - 0.29 11.4 5.0 0.58 10.4 5.0 1.4 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 ACBP PF00887.19 CAM37874.1 - 2.4e-26 91.7 0.1 2.8e-26 91.5 0.1 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein Terminase_6 PF03237.15 CAM37874.1 - 0.11 12.1 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Terminase-like family Attacin_C PF03769.15 CAM37874.1 - 0.11 12.7 0.0 0.12 12.6 0.0 1.0 1 0 0 1 1 1 0 Attacin, C-terminal region ACBP PF00887.19 CAM37876.1 - 1.6e-26 92.3 0.1 1.8e-26 92.2 0.1 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein Terminase_6 PF03237.15 CAM37876.1 - 0.085 12.5 0.0 0.085 12.5 0.0 1.1 1 0 0 1 1 1 0 Terminase-like family Abhydrolase_1 PF00561.20 CAM37877.1 - 0.00087 19.0 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CAM37877.1 - 0.0012 19.5 0.1 0.0016 19.1 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 CAM37877.1 - 0.024 14.3 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein EF-hand_13 PF17958.1 CAM37878.1 - 2.6e-21 75.2 0.0 6.2e-21 74.0 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 CAM37878.1 - 5.1e-19 68.5 1.3 1.4e-15 57.5 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CAM37878.1 - 5.3e-05 22.8 0.2 0.0012 18.6 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 CAM37878.1 - 0.00015 21.1 0.2 0.00075 18.9 0.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 CAM37878.1 - 0.00062 19.1 0.0 0.0036 16.8 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 CAM37878.1 - 0.07 13.0 0.0 0.41 10.5 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair VASt PF16016.5 CAM37879.1 - 5.9e-16 59.2 0.0 8.8e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain DNAPolymera_Pol PF11590.8 CAM37879.1 - 0.093 12.6 0.1 0.22 11.4 0.1 1.6 1 0 0 1 1 1 0 DNA polymerase catalytic subunit Pol GRAM PF02893.20 CAM37880.1 - 1.9e-22 79.3 4.8 3.8e-12 46.1 0.3 2.4 2 0 0 2 2 2 2 GRAM domain VASt PF16016.5 CAM37880.1 - 1.5e-15 57.9 0.0 3.2e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain DNAPolymera_Pol PF11590.8 CAM37880.1 - 1.1 9.2 3.2 0.49 10.3 0.1 2.0 2 0 0 2 2 2 0 DNA polymerase catalytic subunit Pol Mucin15 PF15672.5 CAM37881.1 - 2 7.8 11.1 0.79 9.2 7.9 1.7 1 1 1 2 2 2 0 Cell-membrane associated Mucin15 Pkinase PF00069.25 CAM37882.1 - 1.1e-67 228.2 0.0 1.4e-67 227.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM37882.1 - 1.4e-38 132.7 0.0 1.9e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 CAM37882.1 - 1e-31 108.9 0.0 4e-17 62.2 0.0 2.6 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 CAM37882.1 - 1.1e-08 34.7 0.0 1.4e-07 31.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CAM37882.1 - 0.00024 20.0 0.1 0.00035 19.5 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CAM37882.1 - 0.00084 18.4 0.2 0.0013 17.8 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CAM37882.1 - 0.0012 18.8 0.7 0.029 14.3 0.0 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CAM37882.1 - 0.11 11.5 0.1 0.18 10.8 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 VID27 PF08553.10 CAM37883.1 - 6.3e-30 104.4 0.0 1e-29 103.7 0.0 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain Pkinase PF00069.25 CAM37886.1 - 2.8e-23 82.6 0.0 6.8e-12 45.3 0.0 4.1 4 0 0 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.17 CAM37886.1 - 0.00066 19.0 0.0 0.014 14.7 0.0 2.6 3 0 0 3 3 3 1 Protein tyrosine kinase SLATT_2 PF18183.1 CAM37888.1 - 0.0098 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain 2 DUF1451 PF07295.11 CAM37888.1 - 0.33 11.0 2.7 0.4 10.7 0.0 2.4 3 0 0 3 3 3 0 Zinc-ribbon containing domain Methyltransf_16 PF10294.9 CAM37889.2 - 8.8e-19 67.9 0.0 1.9e-14 53.8 0.0 2.8 2 1 1 3 3 3 2 Lysine methyltransferase MTS PF05175.14 CAM37889.2 - 0.064 12.8 0.6 0.24 11.0 0.2 2.1 1 1 1 2 2 2 0 Methyltransferase small domain Myb_DNA-binding PF00249.31 CAM37890.1 - 1.2e-19 70.2 4.0 3.2e-11 43.2 0.3 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CAM37890.1 - 3.7e-14 52.7 10.7 1.4e-08 34.8 0.3 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF4452 PF14618.6 CAM37890.1 - 0.0023 17.8 0.7 0.0023 17.8 0.7 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4452) Myb_DNA-bind_4 PF13837.6 CAM37890.1 - 0.037 14.4 4.0 1.4 9.4 0.1 3.6 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain IMPDH PF00478.25 CAM37892.1 - 2.9e-145 483.6 5.4 3.3e-145 483.4 5.4 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 CAM37892.1 - 6.7e-11 42.5 0.0 0.00077 19.9 0.0 2.7 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 CAM37892.1 - 1.1e-07 31.6 8.2 0.00033 20.2 8.8 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 CAM37892.1 - 1.5e-06 27.5 12.0 3.3e-06 26.4 12.0 1.7 1 1 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 CAM37892.1 - 0.00037 20.0 2.3 0.018 14.5 0.1 2.3 1 1 1 2 2 2 2 Histidine biosynthesis protein Glu_synthase PF01645.17 CAM37892.1 - 0.00082 18.6 5.3 0.0015 17.7 5.3 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 CAM37892.1 - 0.0021 17.4 7.2 0.0045 16.3 1.0 2.4 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 CAM37892.1 - 0.0031 16.8 4.6 0.024 13.8 0.7 2.3 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase NanE PF04131.14 CAM37892.1 - 0.1 11.7 3.5 2 7.5 0.2 2.8 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase G3P_antiterm PF04309.12 CAM37892.1 - 0.12 11.8 0.8 0.74 9.2 0.1 2.3 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator PcrB PF01884.17 CAM37892.1 - 2.4 7.6 8.1 3.1 7.2 0.1 3.6 3 1 1 4 4 4 0 PcrB family Lysine_decarbox PF03641.14 CAM37893.2 - 1.4e-27 96.4 0.5 2.1e-27 95.8 0.5 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 CAM37893.2 - 4.1e-10 39.5 1.3 6.1e-10 38.9 1.3 1.2 1 0 0 1 1 1 1 SLOG cluster4 family ABM PF03992.16 CAM37893.2 - 1.3e-07 31.7 0.1 3.2e-07 30.3 0.1 1.7 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Baseplate_J PF04865.14 CAM37893.2 - 0.017 14.3 0.2 0.025 13.7 0.2 1.2 1 0 0 1 1 1 0 Baseplate J-like protein LSDAT_prok PF18171.1 CAM37893.2 - 0.03 13.6 0.4 0.057 12.7 0.2 1.5 2 0 0 2 2 2 0 SLOG in TRPM, prokaryote MutL PF13941.6 CAM37893.2 - 0.095 11.3 0.2 0.2 10.2 0.2 1.5 2 0 0 2 2 2 0 MutL protein Methyltransf_30 PF05430.11 CAM37893.2 - 0.12 12.3 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Kinesin PF00225.23 CAM37894.2 - 4.9e-103 344.6 0.1 4.9e-103 344.6 0.1 2.2 2 1 2 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 CAM37894.2 - 5.9e-26 91.2 0.0 5.9e-26 91.2 0.0 2.4 3 0 0 3 3 3 1 Microtubule binding Spc42p PF11544.8 CAM37894.2 - 0.0015 18.4 2.2 0.0015 18.4 2.2 5.5 4 2 2 6 6 6 1 Spindle pole body component Spc42p DUF4988 PF16378.5 CAM37894.2 - 0.17 11.5 5.0 0.23 11.1 0.6 3.2 2 0 0 2 2 2 0 Domain of unknown function MISS PF15822.5 CAM37894.2 - 0.23 11.3 0.6 0.37 10.6 0.6 1.2 1 0 0 1 1 1 0 MAPK-interacting and spindle-stabilising protein-like DUF4806 PF16064.5 CAM37894.2 - 0.31 11.3 3.7 0.96 9.8 1.2 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4806) DUF3402 PF11882.8 CAM37896.1 - 7.9 5.5 7.0 0.57 9.2 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3402) FYVE PF01363.21 CAM37897.1 - 6.3e-11 42.3 6.0 6.3e-11 42.3 6.0 2.4 2 0 0 2 2 2 1 FYVE zinc finger PI3_PI4_kinase PF00454.27 CAM37897.1 - 1.5e-09 38.1 0.4 1.3e-07 31.7 0.1 2.4 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase IBR PF01485.21 CAM37897.1 - 0.11 12.8 2.5 0.3 11.3 2.5 1.8 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain OrfB_Zn_ribbon PF07282.11 CAM37897.1 - 0.12 12.3 3.0 0.44 10.5 3.0 1.9 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.6 CAM37897.1 - 0.49 9.9 2.2 5.3 6.6 2.2 2.5 1 1 0 1 1 1 0 zinc-ribbon domain DUF3449 PF11931.8 CAM37899.1 - 4.8e-38 130.8 0.6 4.8e-38 130.8 0.6 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 CAM37899.1 - 1.6e-09 38.2 0.0 1.1e-08 35.5 0.0 2.3 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 zf-RING_7 PF02591.15 CAM37899.1 - 0.19 11.9 0.0 22 5.4 0.0 2.8 2 0 0 2 2 2 0 C4-type zinc ribbon domain ASH PF15780.5 CAM37900.2 - 4.3e-49 164.7 61.9 5e-07 29.8 0.0 31.6 36 0 0 36 36 35 10 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 CAM37900.2 - 5.6e-20 71.4 29.7 0.0012 18.9 0.0 13.8 16 0 0 16 16 16 4 Flagellar-associated PapD-like DUF1573 PF07610.11 CAM37900.2 - 3.5e-16 59.0 0.0 2.3 8.3 0.1 13.6 17 0 0 17 17 16 1 Protein of unknown function (DUF1573) Motile_Sperm PF00635.26 CAM37900.2 - 5.8e-13 48.7 7.0 17 5.3 0.0 14.1 17 0 0 17 17 17 0 MSP (Major sperm protein) domain TMEM131_like PF12371.8 CAM37900.2 - 5.9e-08 32.9 9.8 4.1 7.7 0.0 10.9 12 0 0 12 12 11 1 Transmembrane protein 131-like DUF5001 PF16392.5 CAM37900.2 - 8.5e-05 22.4 2.0 6.9 6.7 0.0 7.0 6 0 0 6 6 6 1 Ig-like domain AAA_33 PF13671.6 CAM37900.2 - 0.00042 20.5 0.0 0.0013 18.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain MYCBPAP PF14646.6 CAM37900.2 - 0.0011 18.0 0.0 21 3.9 0.0 5.9 6 0 0 6 6 6 0 MYCBP-associated protein family AAA_22 PF13401.6 CAM37900.2 - 0.0011 19.2 0.0 0.0031 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CAM37900.2 - 0.022 14.1 0.0 0.046 13.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 CAM37900.2 - 0.11 12.8 0.0 0.47 10.8 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 CAM37900.2 - 0.13 12.7 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Trigger_C PF05698.14 CAM37900.2 - 0.47 10.4 1.8 0.9 9.5 1.8 1.3 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus DUF756 PF05506.12 CAM37900.2 - 1.4 9.9 8.7 54 4.8 0.0 7.6 7 1 1 8 8 7 0 Domain of unknown function (DUF756) TGT PF01702.18 CAM37901.1 - 2.5e-124 415.0 0.0 3.7e-92 309.2 0.0 2.1 1 1 1 2 2 2 2 Queuine tRNA-ribosyltransferase DnaJ PF00226.31 CAM37902.1 - 2.6e-19 69.1 0.1 4.8e-19 68.2 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain DUF3137 PF11335.8 CAM37902.1 - 0.16 11.9 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3137) Pkinase PF00069.25 CAM37903.2 - 5.8e-30 104.5 0.0 2.7e-28 99.1 0.0 2.9 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM37903.2 - 5.9e-08 32.3 0.0 4.7e-05 22.8 0.0 2.5 1 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CAM37903.2 - 0.0025 17.8 0.1 0.0095 15.9 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CAM37903.2 - 0.14 11.5 0.0 0.57 9.4 0.0 1.9 3 0 0 3 3 3 0 Kinase-like IFT46_B_C PF12317.8 CAM37904.2 - 2.4e-80 269.3 0.1 3.6e-80 268.7 0.1 1.3 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal FAM176 PF14851.6 CAM37904.2 - 0.14 11.8 4.8 1.1 8.9 0.2 2.3 2 0 0 2 2 2 0 FAM176 family GEN1_C PF18380.1 CAM37904.2 - 7.2 7.6 10.8 8 7.4 0.5 3.3 3 0 0 3 3 3 0 Holliday junction resolvase Gen1 C-terminal domain LRR_6 PF13516.6 CAM37905.1 - 7.3e-12 44.3 1.7 0.081 13.0 0.0 5.7 6 0 0 6 6 6 4 Leucine Rich repeat LRR_4 PF12799.7 CAM37905.1 - 2.1e-06 28.0 5.0 0.22 12.0 0.1 4.6 4 1 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CAM37905.1 - 0.0014 18.8 0.3 80 4.4 0.0 5.2 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_8 PF13855.6 CAM37905.1 - 0.037 13.8 4.7 15 5.5 0.0 4.3 3 3 0 3 3 3 0 Leucine rich repeat DUF3729 PF12526.8 CAM37905.1 - 1.7 10.2 7.2 0.86 11.2 4.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3729) Acyltransferase PF01553.21 CAM37906.1 - 4.4e-15 55.5 0.0 7.4e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 CAM37906.1 - 1.8e-05 24.7 0.1 0.0013 18.7 0.0 2.7 1 1 1 2 2 2 1 Acyltransferase C-terminus Sec63 PF02889.16 CAM37907.2 - 5.7e-52 176.4 0.0 1.2e-49 168.8 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 CAM37907.2 - 6e-32 110.8 0.4 1.5e-23 83.5 0.4 3.0 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 CAM37907.2 - 8e-11 42.2 0.0 3.1e-09 37.1 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_PWI PF18149.1 CAM37907.2 - 2e-08 34.4 0.0 5.8e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 N-terminal helicase PWI domain Helicase_C PF00271.31 CAM37907.2 - 1.6e-07 31.7 0.0 1.1e-06 29.0 0.0 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_16 PF13191.6 CAM37907.2 - 0.00081 19.8 0.9 2.5 8.5 0.1 3.7 3 0 0 3 3 3 2 AAA ATPase domain Mg_chelatase PF01078.21 CAM37907.2 - 0.17 11.2 0.8 5.7 6.3 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 CAM37907.2 - 0.29 11.5 3.1 1.6 9.1 0.9 3.0 3 0 0 3 3 3 0 AAA domain FH2 PF02181.23 CAM37908.1 - 1.3e-46 159.4 0.0 2e-46 158.8 0.0 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain CUE PF02845.16 CAM37908.1 - 0.0021 17.7 0.0 0.01 15.5 0.0 2.2 2 0 0 2 2 2 1 CUE domain Med9 PF07544.13 CAM37908.1 - 0.0033 17.5 0.2 0.011 15.9 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 RPW8 PF05659.11 CAM37908.1 - 0.086 12.5 0.6 0.32 10.7 0.3 1.9 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 PCIF1_WW PF12237.8 CAM37909.2 - 5.1e-34 117.4 0.1 1.3e-32 112.8 0.1 2.8 2 1 0 2 2 2 1 Phosphorylated CTD interacting factor 1 WW domain TipAS PF07739.13 CAM37910.2 - 0.039 14.5 0.0 0.86 10.2 0.0 2.7 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain META PF03724.16 CAM37911.1 - 1.6e-10 40.9 0.0 1.8e-10 40.7 0.0 1.0 1 0 0 1 1 1 1 META domain eIF-3c_N PF05470.12 CAM37913.1 - 0.041 12.2 0.6 0.06 11.7 0.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus G-patch PF01585.23 CAM37914.1 - 2.7e-12 46.4 0.3 6.4e-12 45.2 0.3 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CAM37914.1 - 0.00088 19.3 0.5 0.00088 19.3 0.5 1.9 2 0 0 2 2 2 1 G-patch domain Nucleo_P87 PF07267.11 CAM37914.1 - 0.088 11.7 2.4 0.1 11.4 2.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Peptidase_S55 PF05580.12 CAM37914.1 - 0.15 12.0 0.0 0.19 11.7 0.0 1.1 1 0 0 1 1 1 0 SpoIVB peptidase S55 Macoilin PF09726.9 CAM37914.1 - 1 7.8 6.6 1.1 7.8 6.6 1.0 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 CAM37914.1 - 3.8 6.2 5.0 4.8 5.8 5.0 1.1 1 0 0 1 1 1 0 Presenilin DBR1 PF05011.13 CAM37916.1 - 7.1e-09 36.2 0.0 1.3e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 CAM37916.1 - 1.9e-05 25.3 0.0 4.6e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase ATP-synt_10 PF05176.14 CAM37917.1 - 0.0031 16.8 0.0 0.0092 15.2 0.0 1.8 1 0 0 1 1 1 1 ATP10 protein DUF1935 PF09149.10 CAM37920.1 - 9.3e-35 119.1 0.1 1.8e-34 118.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) META PF03724.16 CAM37920.1 - 1.1e-26 92.9 0.4 4.9e-09 36.1 0.0 3.4 3 0 0 3 3 3 3 META domain YabA PF06156.13 CAM37920.1 - 0.095 13.3 0.0 0.7 10.6 0.0 2.3 2 0 0 2 2 2 0 Initiation control protein YabA Yae1_N PF09811.9 CAM37920.1 - 2 8.2 3.7 1.1e+02 2.6 0.1 3.2 3 0 0 3 3 3 0 Essential protein Yae1, N terminal PDEase_I PF00233.19 CAM37921.1 - 1.6e-14 54.2 0.0 3.3e-14 53.2 0.0 1.5 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Mak10 PF04112.13 CAM37922.1 - 7.5e-06 25.6 0.0 0.00026 20.5 0.0 2.5 1 1 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase DUF826 PF05696.11 CAM37922.1 - 0.11 12.7 0.8 0.35 11.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF826) GGA_N-GAT PF18308.1 CAM37922.1 - 0.2 11.3 2.6 14 5.4 0.3 2.6 2 0 0 2 2 2 0 GGA N-GAT domain PI3_PI4_kinase PF00454.27 CAM37923.2 - 0.0013 18.6 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase HEAT PF02985.22 CAM37923.2 - 0.13 12.6 2.1 17 6.0 0.1 4.3 2 0 0 2 2 2 0 HEAT repeat DUF3516 PF12029.8 CAM37924.1 - 0.17 10.9 0.2 0.29 10.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) Abhydrolase_1 PF00561.20 CAM37925.1 - 7.6e-24 84.7 0.1 9.4e-18 64.8 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CAM37925.1 - 2.5e-13 49.9 0.2 3e-12 46.3 0.2 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CAM37925.1 - 2.4e-06 28.3 0.1 3.5e-06 27.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CAM37925.1 - 7.6e-05 22.3 0.2 0.051 13.1 0.0 2.6 3 0 0 3 3 3 2 Prolyl oligopeptidase family FSH1 PF03959.13 CAM37925.1 - 0.00012 21.8 0.4 0.00031 20.5 0.4 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Esterase PF00756.20 CAM37925.1 - 0.00022 21.0 0.1 0.00036 20.3 0.1 1.4 1 1 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 CAM37925.1 - 0.00051 19.8 0.3 0.0018 18.1 0.3 1.8 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_2 PF02230.16 CAM37925.1 - 0.0006 19.7 0.1 0.044 13.6 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.10 CAM37925.1 - 0.0009 19.3 0.0 0.0026 17.9 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Ndr PF03096.14 CAM37925.1 - 0.0017 17.1 0.0 0.0023 16.7 0.0 1.2 1 0 0 1 1 1 1 Ndr family Esterase_phd PF10503.9 CAM37925.1 - 0.0079 15.7 0.1 1.7 8.1 0.0 2.3 1 1 0 2 2 2 2 Esterase PHB depolymerase GlcNAc PF11397.8 CAM37926.1 - 1.7e-153 511.3 0.0 2e-153 511.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) DUF2721 PF11026.8 CAM37926.1 - 0.0053 16.6 0.2 0.01 15.7 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) DUF2452 PF10504.9 CAM37926.1 - 0.18 11.2 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) Abhydrolase_1 PF00561.20 CAM37928.1 - 4.3e-18 65.9 0.0 1e-17 64.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CAM37928.1 - 5.2e-09 37.0 0.2 1.7e-08 35.4 0.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CAM37928.1 - 1.4e-08 34.4 0.6 0.003 16.9 0.5 2.8 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 CAM37928.1 - 3.5e-06 27.1 0.1 4.3e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 TAP-like protein Peptidase_S9 PF00326.21 CAM37928.1 - 0.012 15.1 0.0 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Esterase_phd PF10503.9 CAM37928.1 - 0.013 15.0 0.1 0.24 10.8 0.0 2.3 2 0 0 2 2 2 0 Esterase PHB depolymerase Ndr PF03096.14 CAM37928.1 - 0.022 13.5 0.0 0.036 12.8 0.0 1.3 1 0 0 1 1 1 0 Ndr family Ser_hydrolase PF06821.13 CAM37928.1 - 0.054 13.4 0.1 0.14 12.0 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase PGAP1 PF07819.13 CAM37928.1 - 0.079 12.7 0.2 0.12 12.0 0.2 1.2 1 0 0 1 1 1 0 PGAP1-like protein FSH1 PF03959.13 CAM37928.1 - 0.13 11.9 0.1 0.35 10.5 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase (FSH1) DUF2048 PF09752.9 CAM37928.1 - 0.13 11.3 0.0 0.53 9.3 0.0 1.8 1 1 0 1 1 1 0 Abhydrolase domain containing 18 Esterase PF00756.20 CAM37928.1 - 0.15 11.7 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.20 CAM37929.1 - 4.3e-22 79.0 0.0 3.5e-21 76.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CAM37929.1 - 3.3e-16 59.3 0.0 5.1e-16 58.7 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CAM37929.1 - 1.3e-11 45.5 0.9 1.9e-11 45.0 0.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 CAM37929.1 - 5.2e-05 23.3 0.0 0.0001 22.4 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Esterase PF00756.20 CAM37929.1 - 0.00012 21.8 0.0 0.00041 20.1 0.0 1.7 1 1 1 2 2 2 1 Putative esterase Abhydrolase_2 PF02230.16 CAM37929.1 - 0.00021 21.2 0.0 0.02 14.7 0.0 2.3 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Ndr PF03096.14 CAM37929.1 - 0.0021 16.8 0.0 0.0063 15.3 0.0 1.7 2 0 0 2 2 2 1 Ndr family Peptidase_S9 PF00326.21 CAM37929.1 - 0.0023 17.5 0.0 0.39 10.2 0.0 3.2 4 0 0 4 4 4 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 CAM37929.1 - 0.0029 17.1 0.1 0.084 12.4 0.0 2.1 2 0 0 2 2 2 1 Esterase PHB depolymerase DLH PF01738.18 CAM37929.1 - 0.015 14.9 0.0 0.096 12.2 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family Thioesterase PF00975.20 CAM37929.1 - 0.051 13.7 0.1 0.08 13.0 0.1 1.3 1 0 0 1 1 1 0 Thioesterase domain Ser_hydrolase PF06821.13 CAM37929.1 - 0.1 12.5 0.3 0.19 11.6 0.0 1.5 2 0 0 2 2 2 0 Serine hydrolase FIST PF08495.10 CAM37929.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 FIST N domain FSH1 PF03959.13 CAM37929.1 - 0.22 11.2 0.1 0.59 9.8 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase (FSH1) DUF2048 PF09752.9 CAM37929.1 - 0.23 10.5 0.7 0.34 10.0 0.7 1.5 1 1 0 1 1 1 0 Abhydrolase domain containing 18 Abhydrolase_1 PF00561.20 CAM37930.1 - 1.2e-18 67.7 0.0 1.3e-17 64.3 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CAM37930.1 - 1.4e-11 44.1 0.0 6.7e-11 41.9 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CAM37930.1 - 3.4e-08 34.4 3.2 8.9e-08 33.0 3.2 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 CAM37930.1 - 0.0013 18.8 0.0 0.0023 18.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_4 PF08386.10 CAM37930.1 - 0.011 15.8 0.0 0.037 14.1 0.0 1.8 2 0 0 2 2 2 0 TAP-like protein Ndr PF03096.14 CAM37930.1 - 0.17 10.6 0.0 0.33 9.6 0.0 1.3 1 0 0 1 1 1 0 Ndr family PLAC8 PF04749.17 CAM37931.1 - 0.61 11.1 18.6 0.16 13.0 14.2 2.2 2 1 0 2 2 2 0 PLAC8 family KxDL PF10241.9 CAM37932.2 - 0.13 12.6 0.2 0.32 11.3 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein Spc7 PF08317.11 CAM37932.2 - 1.9 7.3 4.4 3 6.6 4.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein UCH PF00443.29 CAM37933.1 - 1.8e-19 70.3 0.0 4.5e-19 68.9 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CAM37933.1 - 5.2e-06 26.3 0.0 1.7e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rubredoxin_2 PF18073.1 CAM37933.1 - 2.4 8.0 5.1 5.4 6.8 5.1 1.6 1 0 0 1 1 1 0 Rubredoxin metal binding domain Steroid_dh PF02544.16 CAM37934.2 - 1.9e-24 86.4 2.1 1.3e-09 38.2 0.0 4.5 4 0 0 4 4 4 4 3-oxo-5-alpha-steroid 4-dehydrogenase Gly_acyl_tr_C PF08444.10 CAM37934.2 - 0.039 14.2 0.0 0.096 12.9 0.0 1.6 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Kinesin PF00225.23 CAM37935.1 - 9e-86 287.8 0.0 1.6e-85 287.0 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CAM37935.1 - 6.2e-23 81.4 0.0 1.3e-22 80.3 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Calpain_III PF01067.22 CAM37935.1 - 2.2e-13 50.7 0.0 3.2e-10 40.4 0.0 2.7 2 0 0 2 2 2 2 Calpain large subunit, domain III Arm PF00514.23 CAM37935.1 - 4.8e-07 29.6 6.4 0.31 11.2 0.1 6.0 7 1 1 8 8 8 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 CAM37935.1 - 0.059 13.8 0.3 1.1 9.7 0.1 2.9 1 1 2 3 3 3 0 HEAT repeats Atx10homo_assoc PF09759.9 CAM37935.1 - 0.1 12.7 2.1 0.79 9.8 0.0 3.4 4 0 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 CAM37935.1 - 0.11 13.0 1.3 0.58 10.7 0.1 3.0 3 1 1 4 4 4 0 HEAT-like repeat Methyltr_RsmB-F PF01189.17 CAM37937.1 - 2e-28 99.4 0.0 1.8e-17 63.6 0.0 4.2 5 0 0 5 5 5 3 16S rRNA methyltransferase RsmB/F WW PF00397.26 CAM37938.2 - 5.7e-09 35.9 0.1 1.1e-08 35.0 0.1 1.5 1 0 0 1 1 1 1 WW domain XRN_N PF03159.18 CAM37939.2 - 1e-69 234.7 0.0 1.5e-69 234.1 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 CAM37939.2 - 5.6e-36 124.4 0.0 1.8e-19 70.0 0.0 2.1 1 1 1 2 2 2 2 Xrn1 helical domain zf-RanBP PF00641.18 CAM37939.2 - 0.00012 21.3 6.4 0.00032 19.9 6.4 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others UDPGP PF01704.18 CAM37940.1 - 7.9e-10 37.9 0.0 2e-09 36.6 0.0 1.5 2 0 0 2 2 2 1 UTP--glucose-1-phosphate uridylyltransferase SR-25 PF10500.9 CAM37941.1 - 1.3 8.6 14.1 0.029 14.0 6.1 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF1843 PF08898.10 CAM37942.1 - 0.57 10.7 6.2 38 4.9 0.0 4.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1843) DUF1192 PF06698.11 CAM37942.1 - 7.2 6.7 11.5 2.1 8.4 2.8 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) PKcGMP_CC PF16808.5 CAM37944.1 - 0.031 14.1 1.4 0.067 13.0 1.4 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ADIP PF11559.8 CAM37944.1 - 0.032 14.3 4.4 0.11 12.6 0.3 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Fez1 PF06818.15 CAM37944.1 - 0.073 13.5 0.5 0.16 12.4 0.5 1.5 1 0 0 1 1 1 0 Fez1 DUF4407 PF14362.6 CAM37944.1 - 0.19 11.0 1.6 0.36 10.1 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SlyX PF04102.12 CAM37944.1 - 0.41 11.3 4.2 2.4 8.8 0.1 2.6 2 0 0 2 2 2 0 SlyX MAD PF05557.13 CAM37944.1 - 0.5 8.7 4.2 1.9 6.8 0.6 2.0 2 0 0 2 2 2 0 Mitotic checkpoint protein TolA_bind_tri PF16331.5 CAM37944.1 - 0.56 10.3 6.9 0.26 11.4 1.5 2.4 2 0 0 2 2 2 0 TolA binding protein trimerisation TRAF_BIRC3_bd PF16673.5 CAM37944.1 - 0.85 9.5 3.6 0.86 9.4 0.3 2.3 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain ATG16 PF08614.11 CAM37944.1 - 0.94 9.7 15.4 0.033 14.4 0.9 3.3 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 CAM37944.1 - 1.2 9.2 3.1 3.9 7.5 3.1 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FlaC_arch PF05377.11 CAM37944.1 - 1.8 9.1 6.2 7.7 7.0 0.6 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) HAP1_N PF04849.13 CAM37944.1 - 2.1 7.5 6.5 0.46 9.6 1.3 2.0 2 0 0 2 2 2 0 HAP1 N-terminal conserved region BRE1 PF08647.11 CAM37944.1 - 2.5 8.3 5.5 0.56 10.3 0.3 2.1 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase CLZ PF16526.5 CAM37944.1 - 2.8 8.4 6.2 16 6.0 0.9 2.6 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ERM PF00769.19 CAM37944.1 - 3.2 7.5 8.6 15 5.3 2.3 2.4 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF4140 PF13600.6 CAM37944.1 - 4.6 7.8 6.5 5.9 7.4 1.0 3.2 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.15 CAM37944.1 - 6 6.7 5.9 1.6 8.6 0.6 2.3 2 0 0 2 2 2 0 Septum formation initiator Methyltransf_32 PF13679.6 CAM37946.1 - 2.3e-13 50.4 1.6 2.1e-06 27.8 0.1 3.0 2 1 0 2 2 2 2 Methyltransferase domain DUF2362 PF10154.9 CAM37946.1 - 0.15 11.0 0.1 0.22 10.4 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Motile_Sperm PF00635.26 CAM37948.1 - 9.5e-11 41.5 0.0 1.9e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Maf1 PF09174.10 CAM37950.1 - 3.1e-26 92.6 0.0 4e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Maf1 regulator Tryp_alpha_amyl PF00234.22 CAM37950.1 - 0.02 15.3 0.0 0.035 14.5 0.0 1.3 1 0 0 1 1 1 0 Protease inhibitor/seed storage/LTP family DUF1771 PF08590.10 CAM37951.1 - 9.5e-20 70.7 3.2 1.8e-19 69.9 3.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) KH_1 PF00013.29 CAM37951.1 - 2.2e-08 33.8 0.5 4.8e-08 32.7 0.5 1.6 1 0 0 1 1 1 1 KH domain Smr PF01713.21 CAM37951.1 - 9.9e-07 29.0 0.0 2.8e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 Smr domain KH_2 PF07650.17 CAM37951.1 - 0.0016 18.2 0.3 0.0042 16.9 0.3 1.8 1 0 0 1 1 1 1 KH domain KN17_SH3 PF18131.1 CAM37951.1 - 0.054 13.6 0.1 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 KN17 SH3-like C-terminal domain SLS PF14611.6 CAM37951.1 - 0.13 12.0 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator TPR_2 PF07719.17 CAM37953.1 - 1.3e-11 43.7 5.6 0.0024 17.9 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 CAM37953.1 - 1e-07 31.8 0.0 0.13 12.7 0.0 4.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CAM37953.1 - 1.7e-07 30.9 0.0 0.043 14.0 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 CAM37953.1 - 2.9e-06 26.9 0.1 0.19 11.6 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 CAM37953.1 - 0.00043 20.9 38.4 0.29 12.1 0.0 9.9 8 2 3 11 11 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 CAM37953.1 - 0.0023 18.5 15.4 0.0099 16.5 0.1 6.0 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 CAM37953.1 - 0.012 15.5 3.0 14 6.0 0.0 5.1 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 CAM37953.1 - 0.023 14.3 0.0 0.27 10.9 0.0 2.8 2 0 0 2 2 2 0 TPR repeat Clathrin PF00637.20 CAM37953.1 - 0.056 13.3 0.3 0.22 11.4 0.1 2.0 2 0 0 2 2 2 0 Region in Clathrin and VPS TPR_12 PF13424.6 CAM37953.1 - 0.22 11.8 9.7 1.9 8.8 0.0 5.5 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 CAM37953.1 - 0.79 9.9 5.7 1.3 9.2 0.0 4.5 5 1 1 6 6 6 0 Tetratricopeptide repeat GNAT_acetyltr_2 PF13718.6 CAM37954.2 - 2.6e-80 269.1 0.0 5.4e-80 268.0 0.0 1.6 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.14 CAM37954.2 - 1.7e-59 200.6 0.0 4.1e-59 199.4 0.0 1.7 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.11 CAM37954.2 - 4.6e-30 103.4 0.0 1.5e-29 101.8 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.6 CAM37954.2 - 2e-23 83.3 0.0 9e-23 81.2 0.0 1.9 1 1 0 1 1 1 1 Possible tRNA binding domain AAA_30 PF13604.6 CAM37954.2 - 4.3e-05 23.3 0.1 0.00066 19.5 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CAM37954.2 - 0.00063 20.1 0.2 0.0072 16.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain Oscp1 PF10188.9 CAM37955.2 - 5.3e-55 186.2 0.0 6.9e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 Organic solute transport protein 1 eIF2A PF08662.11 CAM37958.1 - 1.2e-12 48.1 0.0 3.1e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A CTP_transf_like PF01467.26 CAM37960.1 - 4.3e-18 65.9 0.0 5.6e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like Cyt-b5 PF00173.28 CAM37961.2 - 9.5e-15 54.5 0.0 1.4e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ALO PF04030.14 CAM37962.1 - 1.8e-60 204.9 2.4 8.1e-56 189.7 0.3 2.2 2 0 0 2 2 2 2 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 CAM37962.1 - 2.7e-21 75.8 0.1 4.5e-21 75.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain SDA1 PF05285.12 CAM37963.1 - 4.6e-76 256.5 41.5 4.6e-76 256.5 41.5 2.6 2 1 0 2 2 2 1 SDA1 NUC130_3NT PF08158.12 CAM37963.1 - 8.1e-12 45.3 0.0 2.6e-11 43.6 0.0 2.0 1 0 0 1 1 1 1 NUC130/3NT domain DUF1828 PF08861.10 CAM37963.1 - 0.28 11.5 3.2 1.2 9.5 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function DUF1828 IQ PF00612.27 CAM37965.1 - 4.3e-09 35.4 42.9 0.013 15.2 0.6 7.1 6 1 0 6 6 6 5 IQ calmodulin-binding motif Inositol_P PF00459.25 CAM37966.1 - 5.2e-49 167.2 0.5 6.5e-49 166.9 0.5 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Peptidase_C65 PF10275.9 CAM37967.1 - 1.5e-62 211.3 0.3 1.7e-62 211.1 0.3 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 CAM37967.1 - 0.00032 21.2 0.2 0.0086 16.6 0.2 2.4 2 1 0 2 2 2 1 OTU-like cysteine protease zf-UDP PF14569.6 CAM37967.1 - 0.17 12.0 0.5 0.66 10.1 0.1 2.0 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-ZPR1 PF03367.13 CAM37968.1 - 1.5e-108 359.7 0.2 2e-55 187.0 0.1 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 CAM37968.1 - 0.0008 19.4 2.7 0.94 9.5 0.1 2.6 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Lamp PF01299.17 CAM37968.1 - 0.028 14.3 0.0 0.073 12.9 0.0 1.6 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) DnaJ_CXXCXGXG PF00684.19 CAM37968.1 - 0.096 13.1 7.9 0.6 10.5 0.8 2.7 2 1 0 2 2 2 0 DnaJ central domain zinc-ribbons_6 PF07191.12 CAM37968.1 - 1 9.4 8.8 1.5 8.9 0.3 3.3 3 0 0 3 3 3 0 zinc-ribbons DiS_P_DiS PF06750.13 CAM37968.1 - 3.4 7.9 5.6 29 4.9 0.1 3.1 2 1 1 3 3 3 0 Bacterial Peptidase A24 N-terminal domain DUF2387 PF09526.10 CAM37968.1 - 4.4 7.5 7.2 18 5.6 0.8 2.8 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) zf-RRPl_C4 PF17026.5 CAM37968.1 - 4.4 7.4 8.3 0.37 10.9 0.1 3.0 3 1 1 4 4 4 0 Putative ribonucleoprotein zinc-finger pf C4 type Anti-TRAP PF15777.5 CAM37968.1 - 6.2 6.9 8.5 2 8.4 1.0 3.4 3 1 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-ZPR1 PF03367.13 CAM37969.2 - 7.7e-28 97.3 0.0 1.1e-27 96.9 0.0 1.2 1 0 0 1 1 1 1 ZPR1 zinc-finger domain Lamp PF01299.17 CAM37969.2 - 0.0054 16.6 0.0 0.0073 16.2 0.0 1.2 1 0 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) MFS_1 PF07690.16 CAM37971.2 - 1.3e-19 70.4 41.5 1.3e-19 70.4 41.5 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily zf-LITAF-like PF10601.9 CAM37971.2 - 2 8.8 4.6 5.3 7.4 0.1 3.5 2 1 1 3 3 3 0 LITAF-like zinc ribbon domain Ion_trans PF00520.31 CAM37972.2 - 1.9e-09 37.1 14.5 3.3e-07 29.8 11.4 2.1 2 0 0 2 2 2 2 Ion transport protein RabGAP-TBC PF00566.18 CAM37973.2 - 1.1e-18 67.6 0.1 1.9e-18 67.0 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ferrochelatase PF00762.19 CAM37974.1 - 6.7e-66 222.5 0.0 2.2e-50 171.5 0.0 2.1 2 0 0 2 2 2 2 Ferrochelatase CDC27 PF09507.10 CAM37975.1 - 1.8 7.9 8.3 2.5 7.4 8.3 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 KAR9 PF08580.10 CAM37975.1 - 5.8 5.3 8.8 6.8 5.1 8.8 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Peptidase_A17 PF05380.13 CAM37976.1 - 0.0005 20.1 0.1 0.017 15.1 0.0 2.3 1 1 1 2 2 2 1 Pao retrotransposon peptidase RVT_1 PF00078.27 CAM37976.1 - 0.00055 19.5 0.0 0.0015 18.1 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RPAP1_N PF08621.10 CAM37976.1 - 0.44 10.4 2.0 0.49 10.2 0.3 1.9 2 0 0 2 2 2 0 RPAP1-like, N-terminal PPR_2 PF13041.6 CAM37977.1 - 4.3e-48 161.3 8.0 5.5e-08 32.9 0.0 12.3 9 4 5 14 14 14 8 PPR repeat family PPR PF01535.20 CAM37977.1 - 2.3e-42 140.3 16.9 0.0025 18.0 0.0 17.2 18 0 0 18 18 18 11 PPR repeat PPR_3 PF13812.6 CAM37977.1 - 2.1e-24 85.4 0.6 6.2e-05 23.0 0.0 9.0 8 1 0 9 9 9 5 Pentatricopeptide repeat domain PPR_1 PF12854.7 CAM37977.1 - 4.1e-16 58.4 11.5 0.043 13.5 0.0 12.1 14 0 0 14 14 14 4 PPR repeat PPR_long PF17177.4 CAM37977.1 - 3.7e-12 46.1 0.1 0.025 14.0 0.0 5.1 3 1 1 5 5 5 4 Pentacotripeptide-repeat region of PRORP ERAP1_C PF11838.8 CAM37977.1 - 3.6e-06 26.7 2.0 2.5 7.6 0.0 4.6 3 1 1 4 4 4 3 ERAP1-like C-terminal domain TPR_14 PF13428.6 CAM37977.1 - 0.00043 20.9 8.8 4.7 8.3 0.2 6.2 4 2 2 6 6 6 2 Tetratricopeptide repeat SPOB_a PF14689.6 CAM37977.1 - 0.0022 17.6 1.3 4.2 7.2 0.1 5.0 5 1 1 6 6 6 1 Sensor_kinase_SpoOB-type, alpha-helical domain ATP13 PF12921.7 CAM37977.1 - 0.0041 17.0 0.0 30 4.5 0.0 5.2 4 2 1 5 5 5 0 Mitochondrial ATPase expression ECSIT PF06239.11 CAM37977.1 - 0.058 12.5 0.1 8 5.5 0.0 3.7 2 1 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway RNA_pol_Rpb4 PF03874.16 CAM37977.1 - 0.085 13.2 0.0 36 4.7 0.0 3.8 4 0 0 4 4 3 0 RNA polymerase Rpb4 TPR_12 PF13424.6 CAM37977.1 - 0.26 11.6 7.2 1.4 9.2 0.8 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat MDD_C PF18376.1 CAM37978.1 - 7.8e-54 182.3 0.1 1.4e-53 181.4 0.1 1.4 2 0 0 2 2 2 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 CAM37978.1 - 9.1e-05 22.6 6.7 0.00015 21.9 5.2 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain DUF1819 PF08849.11 CAM37978.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) RRM_1 PF00076.22 CAM37979.1 - 9.1e-05 22.2 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2HC_2 PF13913.6 CAM37983.1 - 3e-35 119.4 62.1 5.3e-09 35.8 1.8 8.4 9 0 0 9 9 9 6 zinc-finger of a C2HC-type DZR PF12773.7 CAM37983.1 - 7.3e-15 54.7 58.1 1.7e-10 40.7 12.4 8.5 7 1 0 7 7 7 3 Double zinc ribbon zf-ribbon_3 PF13248.6 CAM37983.1 - 0.0067 15.8 1.8 0.0067 15.8 1.8 10.0 9 1 3 12 12 12 5 zinc-ribbon domain zinc-ribbons_6 PF07191.12 CAM37983.1 - 0.036 14.0 1.0 0.03 14.3 6.3 8.3 10 0 0 10 10 10 0 zinc-ribbons NOB1_Zn_bind PF08772.11 CAM37983.1 - 0.037 14.2 1.0 0.037 14.2 1.0 6.6 6 1 1 7 7 7 0 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_2 PF13240.6 CAM37983.1 - 0.048 13.4 60.5 0.34 10.7 2.6 9.4 9 0 0 9 9 9 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 CAM37983.1 - 0.36 11.6 48.0 0.53 11.1 0.3 7.6 8 1 1 9 9 9 0 zinc-ribbon family Nairovirus_M PF07948.11 CAM37983.1 - 0.59 8.3 2.4 1.8 6.7 0.2 2.8 3 0 0 3 3 3 0 Nairovirus M polyprotein-like 3Beta_HSD PF01073.19 CAM37984.1 - 3.5e-10 39.4 0.0 5.1e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 CAM37984.1 - 6.1e-06 26.2 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CAM37984.1 - 0.00018 21.0 0.1 0.00044 19.8 0.1 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 CAM37984.1 - 0.00072 18.7 0.0 0.19 10.8 0.0 3.0 2 1 0 2 2 2 2 RmlD substrate binding domain Semialdhyde_dh PF01118.24 CAM37984.1 - 0.0027 18.1 0.0 0.0057 17.1 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 CAM37984.1 - 0.0079 15.8 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Glyco_hydro_31 PF01055.26 CAM37985.1 - 1.1e-138 463.2 7.0 1.3e-138 462.9 7.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CAM37985.1 - 1.2e-17 63.9 0.3 8.7e-16 58.0 0.1 2.8 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 CAM37985.1 - 1.4e-06 28.5 0.4 3.9e-06 27.0 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) OFeT_1 PF16955.5 CAM37986.1 - 0.2 11.3 0.0 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron uptake permease, iron-lead transporter DUF726 PF05277.12 CAM37987.2 - 3.8e-59 200.3 24.1 3.2e-56 190.7 0.0 3.2 2 1 1 3 3 3 3 Protein of unknown function (DUF726) VirJ PF06057.11 CAM37987.2 - 0.0025 17.7 0.0 2.9 7.7 0.0 2.3 2 0 0 2 2 2 2 Bacterial virulence protein (VirJ) DUF3089 PF11288.8 CAM37987.2 - 0.037 13.6 0.2 0.41 10.2 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3089) DUF21 PF01595.20 CAM37989.1 - 2.4e-28 99.0 0.1 4.7e-28 98.1 0.1 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 CAM37989.1 - 2.7e-08 34.2 0.6 0.0014 19.0 0.1 3.8 4 0 0 4 4 4 3 CBS domain cNMP_binding PF00027.29 CAM37989.1 - 8.5e-05 22.6 0.0 0.00023 21.2 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF21 PF01595.20 CAM37990.2 - 1.6e-40 138.7 0.1 2.9e-40 137.8 0.1 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain cNMP_binding PF00027.29 CAM37990.2 - 0.0093 16.0 0.0 0.026 14.6 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain CBS PF00571.28 CAM37990.2 - 0.15 12.6 0.3 25 5.4 0.0 3.2 3 0 0 3 3 3 0 CBS domain Metallophos PF00149.28 CAM37991.2 - 6.4e-30 105.2 0.2 1e-29 104.5 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 CAM37991.2 - 5.6e-20 71.4 0.4 1.3e-19 70.2 0.2 1.8 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_1 PF00515.28 CAM37991.2 - 3.5e-15 55.1 1.0 5.1e-05 22.9 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CAM37991.2 - 6.5e-13 47.7 2.9 0.0014 18.6 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 CAM37991.2 - 1.3e-07 31.2 0.5 0.31 11.4 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CAM37991.2 - 5.4e-07 29.2 0.4 0.017 14.8 0.0 2.8 2 0 0 2 2 2 2 TPR repeat TPR_17 PF13431.6 CAM37991.2 - 9.8e-05 22.5 0.1 0.0025 18.1 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CAM37991.2 - 0.00014 22.4 2.0 0.065 14.1 0.1 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CAM37991.2 - 0.00045 20.7 1.0 0.00091 19.7 1.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 CAM37991.2 - 0.0005 20.7 2.9 0.025 15.2 2.2 2.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 CAM37991.2 - 0.0015 18.6 0.4 0.046 13.9 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat Paf67 PF10255.9 CAM37991.2 - 0.022 13.8 0.0 0.032 13.2 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 TPR_12 PF13424.6 CAM37991.2 - 0.048 14.0 2.6 2.9 8.2 0.4 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat Lipase_3 PF01764.25 CAM37992.1 - 7.2e-12 45.4 0.0 1.3e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CAM37992.1 - 0.00031 21.4 0.1 0.00081 20.1 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family RRM_1 PF00076.22 CAM37993.1 - 6.7e-29 99.5 0.0 2.7e-16 59.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CAM37993.1 - 0.0037 16.9 0.0 0.062 12.9 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CAM37993.1 - 0.0043 17.0 0.0 1.6 8.8 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CAM37993.1 - 0.0044 17.1 0.0 0.54 10.4 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif Limkain-b1 PF11608.8 CAM37993.1 - 0.089 12.9 0.2 8.3 6.6 0.0 3.0 2 1 1 3 3 3 0 Limkain b1 PHM7_cyt PF14703.6 CAM37993.1 - 0.2 11.8 0.5 43 4.3 0.0 3.0 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter RRM_1 PF00076.22 CAM37994.1 - 6.3e-29 99.6 0.0 2.7e-16 59.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAM37994.1 - 0.0044 17.1 0.0 0.55 10.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CAM37994.1 - 0.0046 16.9 0.0 1.6 8.8 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 CAM37994.1 - 0.0084 15.7 0.0 0.14 11.7 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 CAM37995.1 - 2.1e-30 104.3 0.0 3.4e-17 62.0 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAM37995.1 - 0.0048 17.0 0.0 0.022 14.8 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 CAM37995.1 - 0.0087 16.0 0.0 2.3 8.3 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.8 CAM37995.1 - 0.052 13.2 0.2 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Amino_oxidase PF01593.24 CAM37996.1 - 1.8e-11 44.0 0.1 5.5e-11 42.4 0.1 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CAM37996.1 - 1.1e-07 31.9 0.8 3.2e-07 30.5 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CAM37996.1 - 0.018 14.3 0.1 0.032 13.5 0.1 1.4 1 0 0 1 1 1 0 Thi4 family HhH-GPD PF00730.25 CAM37996.1 - 0.026 15.0 0.0 0.048 14.1 0.0 1.4 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein NAD_binding_9 PF13454.6 CAM37996.1 - 0.031 14.3 0.0 0.11 12.5 0.0 2.0 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 CAM37996.1 - 0.063 12.5 0.1 0.16 11.2 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CAM37996.1 - 0.071 12.3 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CAM37996.1 - 0.23 10.1 0.1 0.38 9.4 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Aha1_N PF09229.11 CAM37997.1 - 2.3e-24 86.2 0.1 3.4e-24 85.6 0.1 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 CAM37997.1 - 6.3e-19 68.4 0.0 1.9e-18 66.9 0.0 1.8 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Pkinase PF00069.25 CAM38003.1 - 5.4e-58 196.4 0.0 6.3e-58 196.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM38003.1 - 1.2e-23 83.7 0.0 1.7e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 CAM38003.1 - 0.0044 16.6 0.0 0.0079 15.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CAM38003.1 - 0.0065 16.4 0.0 0.027 14.4 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CAM38003.1 - 0.041 13.2 0.0 0.077 12.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UDPGT PF00201.18 CAM38003.1 - 0.12 11.1 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase HEAT_EZ PF13513.6 CAM38004.2 - 0.12 12.9 1.9 5.1 7.7 0.4 3.8 3 1 1 4 4 4 0 HEAT-like repeat CoaE PF01121.20 CAM38005.2 - 1.5e-21 76.9 0.0 3.2e-06 27.0 0.0 4.1 4 0 0 4 4 4 4 Dephospho-CoA kinase AAA_18 PF13238.6 CAM38005.2 - 0.01 16.4 0.0 0.036 14.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF866 PF05907.13 CAM38007.1 - 0.1 12.5 1.7 0.3 11.0 0.2 2.1 1 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF866) DUF35_N PF12172.8 CAM38007.1 - 0.25 11.3 7.8 0.14 12.1 2.1 2.6 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF4379 PF14311.6 CAM38008.1 - 2.2e-17 63.1 9.7 1.3e-08 35.0 1.8 2.8 2 1 0 2 2 2 2 Probable Zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 CAM38008.1 - 0.0014 18.6 7.8 0.063 13.3 2.0 3.4 3 0 0 3 3 3 1 Transposase zinc-ribbon domain DUF5313 PF17240.2 CAM38008.1 - 0.009 16.4 0.1 0.017 15.5 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5313) Elf1 PF05129.13 CAM38008.1 - 0.023 14.7 1.5 2.8 8.1 0.1 2.9 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like zf-HC5HC2H PF13771.6 CAM38008.1 - 0.061 13.6 2.2 3.2 8.0 0.5 2.7 1 1 1 2 2 2 0 PHD-like zinc-binding domain zinc_ribbon_10 PF10058.9 CAM38008.1 - 0.069 12.9 3.4 10 6.0 0.1 3.3 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-ZPR1 PF03367.13 CAM38008.1 - 0.097 12.5 0.1 0.24 11.2 0.0 1.7 2 0 0 2 2 2 0 ZPR1 zinc-finger domain Zn_Tnp_IS91 PF14319.6 CAM38008.1 - 0.12 12.4 4.5 1.6 8.8 0.2 3.1 3 0 0 3 3 3 0 Transposase zinc-binding domain VATC PF18716.1 CAM38008.1 - 0.59 10.0 7.8 8.5 6.3 3.2 3.2 2 1 0 2 2 2 0 Vms1-associating treble clef domain Zn_ribbon_SprT PF17283.2 CAM38008.1 - 0.97 9.4 17.5 3 7.8 4.3 3.3 3 0 0 3 3 3 0 SprT-like zinc ribbon domain DZR PF12773.7 CAM38008.1 - 1.5 8.9 5.9 1.9 8.5 1.1 2.5 2 1 0 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 CAM38008.1 - 1.9 8.7 8.1 17 5.6 0.2 3.1 2 1 0 2 2 2 0 Zinc ribbon domain Rubredoxin_2 PF18073.1 CAM38008.1 - 1.9 8.3 15.3 2.2 8.1 0.6 3.5 3 0 0 3 3 3 0 Rubredoxin metal binding domain zf-Sec23_Sec24 PF04810.15 CAM38008.1 - 3.1 7.9 10.1 2.9 8.0 0.2 3.6 4 0 0 4 4 4 0 Sec23/Sec24 zinc finger zf-C3HC4_3 PF13920.6 CAM38008.1 - 3.1 7.7 5.5 3.8 7.4 0.3 2.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) CxC5 PF18718.1 CAM38008.1 - 5.2 7.2 8.7 6.2 6.9 0.5 3.3 1 1 3 4 4 4 0 CxC5 like cysteine cluster associated with KDZ transposases DnaJ PF00226.31 CAM38009.1 - 1.8e-14 53.6 0.1 3.1e-14 52.9 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain DUF446 PF04287.12 CAM38009.1 - 0.046 13.8 0.1 0.087 12.9 0.1 1.4 1 0 0 1 1 1 0 tRNA pseudouridine synthase C FAM221 PF14753.6 CAM38010.1 - 2.3e-14 53.4 18.3 5.7e-13 48.9 1.2 3.5 4 0 0 4 4 4 3 Protein FAM221A/B NOB1_Zn_bind PF08772.11 CAM38010.1 - 0.0049 17.0 0.7 0.0049 17.0 0.7 2.5 2 0 0 2 2 2 1 Nin one binding (NOB1) Zn-ribbon like ATP12 PF07542.11 CAM38011.1 - 1.3e-18 67.4 0.0 2.3e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 ATP12 chaperone protein PPIP5K2_N PF18086.1 CAM38011.1 - 0.16 12.2 0.1 2.4 8.4 0.1 2.6 2 0 0 2 2 2 0 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain Peptidase_C13 PF01650.18 CAM38012.1 - 5.2e-35 121.2 0.0 9.8e-35 120.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase C13 family TTL PF03133.15 CAM38013.1 - 3.3e-79 266.1 0.0 4.7e-79 265.6 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CAM38013.1 - 8.6e-06 25.2 0.0 0.0015 17.9 0.0 2.9 3 0 0 3 3 3 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CAM38013.1 - 0.0051 16.1 0.0 0.022 14.0 0.0 1.9 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp DUF3884 PF13024.6 CAM38013.1 - 0.085 12.4 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3884) HEAT_2 PF13646.6 CAM38014.1 - 0.0039 17.5 0.3 0.37 11.2 0.0 3.4 3 0 0 3 3 3 1 HEAT repeats Nuc_sug_transp PF04142.15 CAM38016.1 - 8.8e-70 235.4 15.4 8.7e-61 205.8 5.7 2.6 2 1 0 2 2 2 2 Nucleotide-sugar transporter UAA PF08449.11 CAM38016.1 - 1e-06 28.2 0.1 2.5e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 CAM38016.1 - 3.3e-06 27.3 2.1 3.3e-06 27.3 2.1 3.4 3 0 0 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 CAM38016.1 - 0.0005 19.4 0.9 0.0005 19.4 0.9 2.3 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport PAP2 PF01569.21 CAM38019.1 - 6.2e-25 87.5 3.0 6.2e-25 87.5 3.0 2.0 2 0 0 2 2 2 1 PAP2 superfamily Amastin PF07344.11 CAM38020.1 - 3.5e-52 176.4 10.0 4.2e-52 176.1 10.0 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.20 CAM38020.1 - 0.0015 18.4 8.0 0.0022 17.9 8.0 1.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family DUF2721 PF11026.8 CAM38020.1 - 0.094 12.6 3.9 0.17 11.8 1.6 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) DUF3087 PF11286.8 CAM38020.1 - 1.3 8.5 3.6 0.46 9.9 1.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) Amastin PF07344.11 CAM38021.1 - 2.1e-55 186.8 11.7 2.5e-55 186.6 11.7 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF4293 PF14126.6 CAM38021.1 - 0.17 12.1 4.5 0.34 11.1 4.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) SUR7 PF06687.12 CAM38021.1 - 5.7 6.5 26.5 0.32 10.6 8.3 3.0 1 1 1 3 3 3 0 SUR7/PalI family PAP2 PF01569.21 CAM38022.1 - 1.6e-25 89.4 3.2 1.6e-25 89.4 3.2 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 CAM38023.1 - 1.2e-26 93.1 3.3 1.5e-26 92.8 3.3 1.0 1 0 0 1 1 1 1 PAP2 superfamily LptF_LptG PF03739.14 CAM38023.1 - 0.061 12.2 0.1 0.1 11.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG TMEM132D_C PF15706.5 CAM38023.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Peptidase_S10 PF00450.22 CAM38025.1 - 1.5e-106 357.3 0.3 1.9e-106 357.0 0.3 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Collar PF07484.12 CAM38025.1 - 0.045 13.8 0.3 1.5 8.8 0.0 3.0 3 0 0 3 3 3 0 Phage Tail Collar Domain Ubiquitin_2 PF14560.6 CAM38026.1 - 6e-23 81.1 0.0 1.1e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.25 CAM38026.1 - 6.3e-20 71.0 0.7 1.1e-19 70.2 0.7 1.4 1 0 0 1 1 1 1 CAP-Gly domain ubiquitin PF00240.23 CAM38026.1 - 0.0012 18.6 0.0 0.012 15.4 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin family WD40 PF00400.32 CAM38027.1 - 1.1e-40 136.8 18.6 8.6e-07 29.6 0.2 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM38027.1 - 9e-11 41.9 2.9 0.025 14.8 0.1 5.4 2 1 3 6 6 5 4 Anaphase-promoting complex subunit 4 WD40 domain ABC_tran_CTD PF16326.5 CAM38027.1 - 0.00062 20.0 1.5 0.21 11.9 1.2 2.4 2 0 0 2 2 2 1 ABC transporter C-terminal domain Nup160 PF11715.8 CAM38027.1 - 0.0066 15.2 0.5 1.1 7.8 0.0 2.5 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CAM38027.1 - 0.11 11.4 0.1 7.6 5.4 0.0 3.0 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 CAM38027.1 - 0.31 9.9 6.6 5.2 5.9 0.3 3.0 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain CENP-F_leu_zip PF10473.9 CAM38027.1 - 0.32 11.0 18.6 0.5 10.4 18.6 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ZapB PF06005.12 CAM38027.1 - 0.45 11.0 14.8 0.35 11.3 0.9 2.4 2 1 0 2 2 2 0 Cell division protein ZapB DUF4407 PF14362.6 CAM38027.1 - 1.5 8.1 4.7 2.5 7.4 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 CAM38027.1 - 5.3 7.1 5.7 12 6.0 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) M PF02370.16 CAM38027.1 - 6.8 7.6 6.1 26 5.8 6.1 2.0 1 0 0 1 1 1 0 M protein repeat UDG PF03167.19 CAM38028.1 - 4.8e-18 65.6 0.0 7.1e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily BTB_2 PF02214.22 CAM38029.2 - 4.9e-13 49.2 0.0 7.9e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain PPR_3 PF13812.6 CAM38030.2 - 0.00056 19.9 0.0 0.4 10.8 0.0 3.1 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 CAM38030.2 - 0.17 11.6 0.0 0.52 10.1 0.0 1.8 1 0 0 1 1 1 0 PPR repeat Aconitase PF00330.20 CAM38031.1 - 2.2e-179 597.3 0.0 2.9e-179 596.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CAM38031.1 - 4.6e-42 143.4 0.0 8.3e-42 142.6 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain TACC_C PF05010.14 CAM38032.1 - 0.011 15.5 0.6 0.011 15.5 0.6 3.0 3 0 0 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal FlaC_arch PF05377.11 CAM38032.1 - 2.2 8.7 4.0 55 4.3 0.3 3.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Lectin_N PF03954.14 CAM38032.1 - 5.9 6.6 10.7 1.2 8.8 0.8 3.5 2 1 2 4 4 4 0 Hepatic lectin, N-terminal domain LemA PF04011.12 CAM38032.1 - 7.7 6.4 12.2 0.1 12.5 3.6 2.2 2 1 1 3 3 3 0 LemA family TBCC PF07986.12 CAM38033.1 - 3.9e-34 117.0 0.1 6e-34 116.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C FOP_dimer PF09398.10 CAM38033.1 - 0.00062 20.0 0.0 0.0012 19.1 0.0 1.4 1 0 0 1 1 1 1 FOP N terminal dimerisation domain CAP_C PF08603.11 CAM38033.1 - 0.0048 16.5 1.2 0.0058 16.2 0.3 1.5 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) C terminal LisH_2 PF16045.5 CAM38033.1 - 0.1 11.7 0.2 0.19 10.8 0.2 1.5 1 0 0 1 1 1 0 LisH MRI PF15325.6 CAM38033.1 - 7.9 7.6 10.8 5 8.3 3.4 2.8 3 0 0 3 3 3 0 Modulator of retrovirus infection Phi29_Phage_SSB PF17427.2 CAM38035.1 - 0.025 14.8 0.4 0.089 13.0 0.3 2.1 1 1 0 1 1 1 0 Phage Single-stranded DNA-binding protein MRP-S26 PF14943.6 CAM38035.1 - 0.048 13.6 9.6 0.086 12.7 9.6 1.4 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 V-ATPase_C PF03223.15 CAM38036.1 - 2.7e-84 283.7 1.5 3.3e-84 283.4 1.5 1.0 1 0 0 1 1 1 1 V-ATPase subunit C ASH PF15780.5 CAM38037.1 - 2.9e-28 97.9 6.2 0.0041 17.3 0.0 9.0 8 1 0 8 8 8 6 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 CAM38037.1 - 1.6e-11 44.1 0.1 0.00046 20.2 0.0 7.9 8 2 0 8 8 8 1 Protein of unknown function (DUF1573) PapD-like PF14874.6 CAM38037.1 - 1.1e-09 38.3 8.2 0.0044 17.2 0.0 5.6 6 0 0 6 6 6 2 Flagellar-associated PapD-like Motile_Sperm PF00635.26 CAM38037.1 - 0.00019 21.2 1.4 0.035 13.9 0.0 4.6 4 0 0 4 4 4 1 MSP (Major sperm protein) domain TMEM131_like PF12371.8 CAM38037.1 - 0.0048 17.1 9.2 21 5.4 0.3 6.2 7 0 0 7 7 7 1 Transmembrane protein 131-like PapD_N PF00345.20 CAM38037.1 - 0.044 13.7 0.0 6 6.8 0.0 3.2 3 0 0 3 3 3 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain ECH_1 PF00378.20 CAM38038.1 - 7.1e-31 107.4 0.4 1e-29 103.6 0.1 2.0 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CAM38038.1 - 4.3e-12 46.2 0.2 1.2e-11 44.7 0.2 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase RRM_1 PF00076.22 CAM38039.1 - 1.7e-18 66.2 0.0 3.7e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CAM38039.1 - 0.0068 16.0 0.0 0.018 14.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CAM38039.1 - 0.019 15.0 0.0 0.046 13.7 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CAM38039.1 - 0.023 14.8 0.1 0.088 12.9 0.0 2.1 2 1 0 2 2 2 0 RNA recognition motif RRM_3 PF08777.11 CAM38039.1 - 0.22 11.6 0.0 0.61 10.2 0.0 1.7 1 0 0 1 1 1 0 RNA binding motif FYVE PF01363.21 CAM38040.1 - 1.3e-19 70.1 7.5 1.3e-19 70.1 7.5 4.6 3 2 1 4 4 4 1 FYVE zinc finger zf-RanBP PF00641.18 CAM38040.1 - 1e-13 50.3 62.7 1.8e-06 27.2 2.0 6.7 7 0 0 7 7 7 5 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 CAM38040.1 - 0.00015 21.1 36.0 0.15 11.5 0.4 6.7 6 2 0 6 6 6 5 Vacuolar protein sorting 36 NZF-N zinc-finger domain DZR PF12773.7 CAM38040.1 - 0.0096 15.9 49.8 3.6 7.7 0.5 5.7 3 2 0 3 3 3 1 Double zinc ribbon Ribosomal_S27e PF01667.17 CAM38041.1 - 4.1e-22 77.7 3.0 5e-22 77.4 3.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 FYVE_2 PF02318.16 CAM38041.1 - 0.019 15.2 0.7 0.022 15.0 0.7 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger Zn_Tnp_IS1595 PF12760.7 CAM38041.1 - 0.023 14.7 1.8 0.037 14.0 1.8 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain HypA PF01155.19 CAM38041.1 - 0.12 12.4 1.8 0.14 12.2 1.8 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_4 PF13717.6 CAM38041.1 - 0.17 11.8 4.7 4.1 7.4 4.7 2.4 1 1 0 1 1 1 0 zinc-ribbon domain Dpy-30 PF05186.13 CAM38042.1 - 3.5e-11 42.6 0.3 5.6e-11 42.0 0.3 1.3 1 0 0 1 1 1 1 Dpy-30 motif Peptidase_M41 PF01434.18 CAM38043.1 - 8.1e-47 159.5 1.5 1.2e-46 159.0 1.5 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CAM38043.1 - 3.1e-39 134.4 0.0 5.6e-39 133.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CAM38043.1 - 7.5e-06 26.4 1.0 3.2e-05 24.4 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 CAM38043.1 - 0.00034 20.6 0.1 0.0021 18.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CAM38043.1 - 0.00053 20.3 0.6 0.016 15.5 0.1 3.0 1 1 2 3 3 3 1 AAA domain AAA_2 PF07724.14 CAM38043.1 - 0.00079 19.6 0.1 0.0034 17.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CAM38043.1 - 0.0061 16.3 0.2 0.11 12.3 0.0 3.0 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 CAM38043.1 - 0.0085 15.3 0.0 0.021 14.0 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain Peptidase_M50B PF13398.6 CAM38043.1 - 0.0097 15.6 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase M50B-like Sigma54_activat PF00158.26 CAM38043.1 - 0.011 15.4 0.0 0.033 13.9 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_lid_3 PF17862.1 CAM38043.1 - 0.022 14.5 0.0 0.061 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA+ lid domain Zeta_toxin PF06414.12 CAM38043.1 - 0.036 13.3 0.1 1.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.6 CAM38043.1 - 0.056 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CAM38043.1 - 0.075 12.8 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.9 CAM38043.1 - 0.1 11.8 0.1 0.16 11.2 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 CAM38043.1 - 0.11 11.8 0.1 0.28 10.5 0.1 1.6 1 0 0 1 1 1 0 KaiC NACHT PF05729.12 CAM38043.1 - 0.14 12.0 0.1 0.64 9.9 0.1 2.1 2 0 0 2 2 2 0 NACHT domain Ribosomal_L1 PF00687.21 CAM38044.1 - 4.2e-41 140.9 2.3 5.2e-41 140.6 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Pkinase PF00069.25 CAM38046.1 - 4.9e-75 252.3 0.0 5.5e-75 252.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM38046.1 - 4.6e-39 134.3 0.0 5.5e-39 134.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM38046.1 - 8.8e-10 38.4 0.0 1.7e-09 37.4 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CAM38046.1 - 3.6e-07 29.5 0.0 1.1e-06 27.9 0.1 1.6 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 CAM38046.1 - 1.8e-05 24.8 0.1 0.12 12.3 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CAM38046.1 - 0.0055 16.1 0.1 0.009 15.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Phosducin PF02114.16 CAM38046.1 - 0.1 11.5 0.1 0.14 11.0 0.1 1.2 1 0 0 1 1 1 0 Phosducin Seadorna_VP7 PF07387.11 CAM38046.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Phage_tail_S PF05069.13 CAM38046.1 - 0.15 11.9 0.1 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 Phage virion morphogenesis family DUF421 PF04239.12 CAM38046.1 - 0.15 11.8 1.8 0.22 11.3 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF421) Choline_kinase PF01633.20 CAM38046.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase PA26 PF04636.13 CAM38047.1 - 1e-33 117.0 2.7 2.7e-12 46.4 0.0 3.1 3 0 0 3 3 3 3 PA26 p53-induced protein (sestrin) HEAT PF02985.22 CAM38048.1 - 2.1e-20 71.1 15.5 0.012 15.8 0.0 10.5 11 0 0 11 11 11 6 HEAT repeat HEAT_2 PF13646.6 CAM38048.1 - 1.7e-14 54.0 15.4 0.00051 20.4 0.0 7.1 4 4 2 7 7 7 5 HEAT repeats Cnd1 PF12717.7 CAM38048.1 - 2.3e-05 24.5 0.0 1.1 9.3 0.0 3.9 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CAM38048.1 - 0.0002 21.8 4.5 0.024 15.1 0.0 4.8 5 0 0 5 5 5 1 HEAT-like repeat Adaptin_N PF01602.20 CAM38048.1 - 0.0014 17.3 0.1 2.6 6.5 0.2 3.4 2 1 1 4 4 4 2 Adaptin N terminal region DUF2063 PF09836.9 CAM38048.1 - 0.012 15.9 0.0 0.041 14.1 0.0 2.0 1 0 0 1 1 1 0 Putative DNA-binding domain CLASP_N PF12348.8 CAM38048.1 - 0.05 13.2 0.1 10 5.6 0.0 3.5 2 1 2 4 4 4 0 CLASP N terminal XdhC_CoxI PF02625.16 CAM38049.2 - 0.0059 16.8 0.2 0.019 15.1 0.2 1.9 1 0 0 1 1 1 1 XdhC and CoxI family Citrate_synt PF00285.21 CAM38050.1 - 3.5e-96 322.4 0.0 4.5e-96 322.1 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Cytomega_gL PF01801.16 CAM38050.1 - 0.15 11.5 0.0 0.37 10.1 0.0 1.6 2 0 0 2 2 2 0 Cytomegalovirus glycoprotein L Citrate_synt PF00285.21 CAM38051.1 - 7.6e-95 318.0 0.0 9.1e-95 317.8 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Cytomega_gL PF01801.16 CAM38051.1 - 0.12 11.8 0.0 0.29 10.5 0.0 1.6 2 0 0 2 2 2 0 Cytomegalovirus glycoprotein L PAP2 PF01569.21 CAM38053.1 - 1.2e-26 93.1 3.3 1.5e-26 92.8 3.3 1.0 1 0 0 1 1 1 1 PAP2 superfamily LptF_LptG PF03739.14 CAM38053.1 - 0.061 12.2 0.1 0.1 11.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG TMEM132D_C PF15706.5 CAM38053.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term PAP2 PF01569.21 CAM38054.1 - 1e-22 80.4 0.6 1e-22 80.4 0.6 2.1 1 1 1 2 2 2 1 PAP2 superfamily DUF4233 PF14017.6 CAM38054.1 - 1.7 9.0 12.7 0.57 10.6 9.3 2.0 3 1 0 3 3 3 0 Protein of unknown function (DUF4233) AAA_16 PF13191.6 CAM38055.1 - 0.0094 16.4 5.9 0.018 15.4 0.2 3.6 3 1 0 3 3 3 1 AAA ATPase domain CYLD_phos_site PF16607.5 CAM38055.1 - 0.03 14.2 0.3 0.077 12.8 0.3 1.6 1 0 0 1 1 1 0 Phosphorylation region of CYLD, unstructured DUF4404 PF14357.6 CAM38055.1 - 0.11 13.1 0.9 9.6 6.9 0.4 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Tctex-1 PF03645.13 CAM38056.1 - 6.7e-17 61.6 0.1 1.1e-16 60.9 0.1 1.3 1 0 0 1 1 1 1 Tctex-1 family RNA_pol_Rpo13 PF12136.8 CAM38056.1 - 6.1 6.8 9.5 49 3.9 0.1 2.5 2 0 0 2 2 2 0 RNA polymerase Rpo13 subunit HTH domain GTP_EFTU PF00009.27 CAM38057.1 - 4.7e-53 179.6 0.3 8.1e-53 178.8 0.3 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CAM38057.1 - 9.6e-19 67.7 0.0 1e-17 64.4 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CAM38057.1 - 2.4e-07 31.0 0.5 5.9e-07 29.8 0.5 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CAM38057.1 - 0.0041 17.2 0.0 0.01 15.9 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 CAM38057.1 - 0.065 13.0 0.8 2.5 7.8 0.8 2.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation zf-C2H2_jaz PF12171.8 CAM38059.1 - 1.3e-07 31.7 1.6 2e-07 31.1 1.6 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CAM38059.1 - 2.5e-06 27.7 0.7 4.1e-06 27.0 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CAM38059.1 - 0.0012 19.2 0.1 0.0015 18.8 0.1 1.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.12 CAM38059.1 - 0.013 15.6 0.5 0.021 14.9 0.5 1.3 1 0 0 1 1 1 0 DBF zinc finger zf-U1 PF06220.12 CAM38059.1 - 0.1 12.4 0.3 0.15 11.8 0.3 1.3 1 0 0 1 1 1 0 U1 zinc finger PDZ_6 PF17820.1 CAM38060.1 - 1.7e-07 31.0 0.1 3.8e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CAM38060.1 - 5.6e-05 23.4 0.0 0.00017 21.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CAM38060.1 - 0.1 13.0 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 PDZ domain RNA_pol_Rpb5_C PF01191.19 CAM38061.1 - 1.6e-29 101.6 0.2 3.1e-29 100.6 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 CAM38061.1 - 9.8e-23 80.6 0.0 2.2e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain DUF1860 PF08949.10 CAM38061.1 - 0.21 11.3 0.0 0.31 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1860) RNA_pol_Rpb5_C PF01191.19 CAM38062.1 - 2.7e-22 78.4 0.0 5.8e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 CAM38062.1 - 1.4e-08 35.2 0.0 0.00027 21.4 0.0 2.6 2 0 0 2 2 2 2 RNA polymerase Rpb5, N-terminal domain GMAP PF06540.11 CAM38062.1 - 0.17 12.0 0.2 0.32 11.1 0.2 1.4 1 0 0 1 1 1 0 Galanin message associated peptide (GMAP) Ribosomal_S8 PF00410.19 CAM38063.1 - 3.3e-07 30.3 0.0 5.6e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S8 Goodbye PF17109.5 CAM38063.1 - 0.52 10.8 3.3 6.9 7.2 0.4 2.6 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain CDP-OH_P_transf PF01066.21 CAM38064.1 - 4.9e-17 62.5 0.0 4.9e-17 62.5 0.0 3.6 3 2 0 3 3 3 1 CDP-alcohol phosphatidyltransferase HEAT_EZ PF13513.6 CAM38065.1 - 3.4 8.3 26.2 1.6 9.3 0.0 8.6 11 0 0 11 11 11 0 HEAT-like repeat WD40 PF00400.32 CAM38066.1 - 1.8e-24 85.5 16.0 1.3e-06 29.0 0.1 10.7 11 0 0 11 11 11 6 WD domain, G-beta repeat Utp12 PF04003.12 CAM38066.1 - 4.5e-12 46.2 0.3 1.2e-11 44.8 0.1 1.9 2 0 0 2 2 2 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 CAM38066.1 - 1.1e-10 41.6 0.0 0.044 14.1 0.0 7.1 6 1 0 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1513 PF07433.11 CAM38066.1 - 0.00031 19.9 0.4 0.061 12.4 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF1513) Pro_isomerase PF00160.21 CAM38068.1 - 3.9e-33 114.9 0.0 9.8e-33 113.7 0.0 1.7 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ras PF00071.22 CAM38069.1 - 8.6e-54 181.5 2.1 1.1e-52 177.9 2.1 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CAM38069.1 - 1.7e-35 121.9 0.1 3.2e-35 120.9 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAM38069.1 - 6e-12 45.4 0.0 7.1e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CAM38069.1 - 2.7e-06 26.9 0.0 3.2e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CAM38069.1 - 5e-06 26.6 0.0 1.1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CAM38069.1 - 6.3e-05 22.6 0.7 0.002 17.7 0.7 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CAM38069.1 - 0.0031 17.4 0.1 0.067 13.1 0.1 2.4 1 1 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 CAM38069.1 - 0.0066 16.2 0.2 0.054 13.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 CAM38069.1 - 0.011 15.3 0.1 2.5 7.6 0.0 2.3 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 CAM38069.1 - 0.021 15.2 0.2 0.027 14.9 0.2 1.5 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 CAM38069.1 - 0.04 13.7 0.0 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.22 CAM38069.1 - 0.055 12.6 0.2 0.053 12.7 0.2 1.4 1 1 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.6 CAM38069.1 - 0.057 13.7 0.0 0.099 12.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 CAM38069.1 - 0.059 13.3 0.0 0.095 12.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain DAP3 PF10236.9 CAM38069.1 - 0.07 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 SRPRB PF09439.10 CAM38069.1 - 0.071 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 CAM38069.1 - 0.08 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 CAM38069.1 - 0.083 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CAM38069.1 - 0.12 12.8 0.0 0.61 10.5 0.0 2.1 1 1 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 CAM38069.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 NTPase TniB PF05621.11 CAM38069.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Glyco_trans_1_4 PF13692.6 CAM38070.1 - 6.6e-05 23.4 0.0 0.00026 21.4 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 PPR_2 PF13041.6 CAM38071.1 - 6.7e-05 23.0 0.0 0.11 12.7 0.0 3.4 2 1 1 3 3 3 2 PPR repeat family PPR_long PF17177.4 CAM38071.1 - 0.00035 20.0 1.5 0.0073 15.7 0.5 2.3 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 CAM38071.1 - 0.0004 20.4 0.0 0.031 14.3 0.0 2.7 2 1 0 2 2 2 1 Pentatricopeptide repeat domain PPR PF01535.20 CAM38071.1 - 0.21 11.9 0.1 21 5.7 0.0 3.7 4 0 0 4 4 4 0 PPR repeat ANAPC4_WD40 PF12894.7 CAM38072.2 - 1.9e-05 24.8 0.7 11 6.4 0.1 5.1 4 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CAM38072.2 - 2e-05 25.3 12.3 0.035 15.0 0.6 5.8 5 1 1 6 6 6 2 WD domain, G-beta repeat PD40 PF07676.12 CAM38072.2 - 0.02 14.8 0.0 8.9 6.4 0.0 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Myosin_TH1 PF06017.13 CAM38073.1 - 0.0034 17.1 0.0 0.0059 16.3 0.0 1.3 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding Lectin_N PF03954.14 CAM38073.1 - 0.062 13.0 3.9 0.48 10.2 0.9 2.5 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Halo_GVPC PF05465.13 CAM38073.1 - 0.13 12.5 2.0 0.65 10.3 0.8 2.5 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat GAS PF13851.6 CAM38073.1 - 6.4 6.1 19.3 2.4 7.5 14.2 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ATP-synt_ab PF00006.25 CAM38074.1 - 0.013 15.2 0.0 0.016 14.9 0.0 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Mannosyl_trans2 PF04188.13 CAM38075.2 - 1.3e-31 110.4 31.0 1.3e-20 74.1 15.3 4.1 4 0 0 4 4 4 4 Mannosyltransferase (PIG-V) Nrap_D5 PF17406.2 CAM38076.1 - 1.4e-29 103.0 0.0 2.9e-29 101.9 0.0 1.6 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D4 PF17405.2 CAM38076.1 - 7e-17 61.5 0.1 1.6e-16 60.3 0.1 1.5 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D3 PF17404.2 CAM38076.1 - 1.1e-16 61.4 0.0 2.2e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D2 PF17403.2 CAM38076.1 - 5.6e-06 26.2 0.0 0.00036 20.3 0.0 2.9 3 0 0 3 3 3 1 Nrap protein PAP/OAS-like domain DUF2391 PF09622.10 CAM38076.1 - 0.086 12.2 2.0 9.4 5.5 0.0 3.1 3 1 1 4 4 4 0 Putative integral membrane protein (DUF2391) Cupin_8 PF13621.6 CAM38078.1 - 0.078 12.7 2.2 0.086 12.5 2.2 1.2 1 0 0 1 1 1 0 Cupin-like domain PIN_2 PF10130.9 CAM38078.1 - 0.16 12.2 4.6 0.053 13.7 1.9 1.6 2 0 0 2 2 2 0 PIN domain Plasmid_RAQPRD PF09686.10 CAM38078.1 - 0.8 10.0 6.6 0.98 9.7 1.8 2.7 1 1 1 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) DUF4407 PF14362.6 CAM38078.1 - 1.5 8.1 14.7 2.1 7.6 14.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FUSC PF04632.12 CAM38078.1 - 5.2 5.5 5.0 5.7 5.4 5.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family APG6_N PF17675.1 CAM38078.1 - 9.1 6.8 17.3 2.6 8.6 5.0 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Mito_carr PF00153.27 CAM38080.1 - 1.2e-19 70.0 3.0 9.3e-10 38.3 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Robl_LC7 PF03259.17 CAM38081.2 - 1.2e-21 76.2 0.0 1.5e-21 76.0 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 CAM38081.2 - 0.0061 16.5 0.0 0.0089 15.9 0.0 1.2 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 NikR_C PF08753.11 CAM38081.2 - 0.013 15.7 0.1 0.19 11.9 0.0 2.3 2 0 0 2 2 2 0 NikR C terminal nickel binding domain PhoD PF09423.10 CAM38083.1 - 3.4e-07 29.6 0.1 0.00021 20.5 0.0 2.8 2 1 0 2 2 2 2 PhoD-like phosphatase DUF4396 PF14342.6 CAM38085.2 - 0.19 12.1 0.7 0.3 11.4 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4396) zf-CCCH PF00642.24 CAM38086.1 - 0.00079 19.3 2.4 0.1 12.6 0.2 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CAM38086.1 - 0.00083 19.1 2.7 0.017 14.9 0.3 2.5 2 0 0 2 2 2 1 CCCH-type zinc finger Torus PF16131.5 CAM38086.1 - 0.036 14.7 3.6 0.3 11.8 0.1 2.8 2 0 0 2 2 2 0 Torus domain Opy2 PF09463.10 CAM38086.1 - 6 7.3 6.8 15 6.0 0.5 2.4 2 0 0 2 2 2 0 Opy2 protein zf-CCCH PF00642.24 CAM38087.2 - 0.00028 20.7 9.3 0.11 12.4 0.1 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CAM38087.2 - 0.0066 17.1 0.3 0.12 13.0 0.1 2.3 2 0 0 2 2 2 1 Torus domain zf-CCCH_2 PF14608.6 CAM38087.2 - 0.068 13.7 11.8 0.95 10.0 0.4 3.2 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 CAM38087.2 - 0.12 12.2 12.1 0.92 9.4 0.1 2.8 2 0 0 2 2 2 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CAM38087.2 - 0.31 11.1 16.7 0.39 10.8 0.3 3.0 3 0 0 3 3 3 0 Zinc finger domain zf-CCCH_3 PF15663.5 CAM38087.2 - 0.42 10.8 4.6 11 6.3 1.1 2.5 2 0 0 2 2 2 0 Zinc-finger containing family CDP-OH_P_transf PF01066.21 CAM38088.1 - 1.8e-21 76.7 0.1 1.8e-21 76.7 0.1 2.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase CTP_transf_like PF01467.26 CAM38088.1 - 1.3e-14 54.6 0.0 2.4e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like CUT PF02376.15 CAM38089.1 - 0.054 13.7 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 CUT domain Peptidase_C2 PF00648.21 CAM38090.1 - 7.1e-14 51.5 0.0 5.6e-13 48.6 0.0 2.0 1 1 0 1 1 1 1 Calpain family cysteine protease Vps16_N PF04841.13 CAM38091.1 - 1.4e-27 96.5 0.0 7.2e-27 94.2 0.0 2.1 1 1 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 CAM38091.1 - 3.9e-24 85.3 0.3 3.8e-12 45.9 0.1 2.3 2 0 0 2 2 2 2 Vps16, C-terminal region AAA_28 PF13521.6 CAM38091.1 - 0.13 12.5 0.1 0.46 10.7 0.1 2.0 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 CAM38092.1 - 2.4e-73 246.8 0.0 2.8e-73 246.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM38092.1 - 7.9e-37 126.9 0.0 9.6e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM38092.1 - 3.8e-07 29.7 0.0 4.5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CAM38092.1 - 0.0017 17.2 0.0 0.0093 14.8 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CAM38092.1 - 0.039 13.9 0.0 0.11 12.4 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CAM38092.1 - 0.095 11.6 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain PDEase_I PF00233.19 CAM38093.1 - 1.8e-79 266.8 0.2 1.8e-79 266.8 0.2 2.9 3 0 0 3 3 3 1 3'5'-cyclic nucleotide phosphodiesterase Ank_3 PF13606.6 CAM38094.1 - 3.2e-22 76.2 0.3 0.00037 20.7 0.0 5.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_2 PF12796.7 CAM38094.1 - 5.6e-22 78.1 1.0 4.8e-11 43.1 0.0 3.5 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CAM38094.1 - 4.2e-20 71.8 0.6 1.2e-11 44.8 0.1 4.1 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 CAM38094.1 - 2.3e-19 69.2 1.6 4.6e-05 23.6 0.0 5.4 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 CAM38094.1 - 5.6e-16 58.2 0.1 0.00034 20.9 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Methyltr_RsmB-F PF01189.17 CAM38095.1 - 1.9e-34 119.1 0.0 3.4e-34 118.3 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 CAM38095.1 - 0.00019 21.6 0.0 0.00039 20.6 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase zf-AN1 PF01428.16 CAM38096.1 - 3.6e-16 59.0 32.6 1.2e-09 38.2 8.6 3.1 2 1 1 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 CAM38096.1 - 0.00013 22.3 17.0 0.0085 16.4 3.2 2.7 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain IBR PF01485.21 CAM38096.1 - 0.019 15.2 2.0 0.019 15.2 2.0 2.9 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain zf-HIT PF04438.16 CAM38096.1 - 9.1 6.3 18.1 0.56 10.1 2.7 3.0 3 0 0 3 3 3 0 HIT zinc finger Ras PF00071.22 CAM38097.1 - 5.6e-51 172.4 0.0 1.7e-50 170.8 0.0 1.7 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CAM38097.1 - 1.1e-31 109.5 0.0 3.4e-30 104.7 0.0 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAM38097.1 - 4.7e-11 42.5 0.0 1.2e-09 37.9 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CAM38097.1 - 0.00011 21.6 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 CAM38097.1 - 0.0084 15.9 0.0 0.05 13.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CAM38097.1 - 0.011 15.6 0.1 0.16 11.9 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 CAM38097.1 - 0.021 15.4 0.0 0.025 15.1 0.0 1.5 1 1 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 CAM38097.1 - 0.034 14.2 0.0 0.13 12.3 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase TniB PF05621.11 CAM38097.1 - 0.16 11.4 0.0 0.31 10.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein APG6_N PF17675.1 CAM38098.1 - 0.0082 16.7 1.7 0.0082 16.7 1.7 9.4 3 1 6 9 9 9 2 Apg6 coiled-coil region SOGA PF11365.8 CAM38098.1 - 0.01 16.9 5.0 0.01 16.9 5.0 9.6 7 3 2 10 10 10 0 Protein SOGA zf-C3HC4_3 PF13920.6 CAM38099.1 - 2.4e-16 59.3 11.0 4.2e-16 58.5 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CAM38099.1 - 6.1e-07 29.7 12.7 1.2e-06 28.7 12.7 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CAM38099.1 - 8.1e-07 28.8 12.6 1.5e-06 27.9 12.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CAM38099.1 - 0.0011 18.8 16.0 0.0021 17.8 16.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_2 PF13240.6 CAM38099.1 - 0.0026 17.4 0.8 0.0066 16.1 0.8 1.7 1 0 0 1 1 1 1 zinc-ribbon domain zf-RING_5 PF14634.6 CAM38099.1 - 0.01 15.8 11.9 0.019 14.9 11.9 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Mannitol_dh PF01232.23 CAM38099.1 - 0.06 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Mannitol dehydrogenase Rossmann domain zf-C4H2 PF10146.9 CAM38099.1 - 0.31 11.3 7.8 1.3 9.3 7.8 2.0 1 1 0 1 1 1 0 Zinc finger-containing protein zf-P11 PF03854.14 CAM38099.1 - 0.32 10.7 10.3 0.69 9.6 10.3 1.6 1 1 0 1 1 1 0 P-11 zinc finger DZR PF12773.7 CAM38099.1 - 1.7 8.7 8.6 8.3 6.5 8.9 1.8 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_10 PF16685.5 CAM38099.1 - 2 8.6 9.9 5.1 7.3 9.9 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 TPR_7 PF13176.6 CAM38100.1 - 0.096 12.8 0.4 0.23 11.6 0.4 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat CAP59_mtransfer PF11735.8 CAM38100.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 Cmc1 PF08583.10 CAM38101.1 - 0.006 16.6 2.3 0.013 15.4 2.3 1.6 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF2196 PF09962.9 CAM38103.1 - 0.038 14.0 0.1 0.077 13.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2196) Complex1_LYR PF05347.15 CAM38104.2 - 2.9e-11 43.2 1.9 7.2e-11 42.0 1.9 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CAM38104.2 - 0.024 15.4 0.6 0.11 13.3 0.6 2.2 1 0 0 1 1 1 0 Complex1_LYR-like ProRS-C_1 PF09180.11 CAM38105.1 - 3.4e-23 81.6 1.5 9.8e-23 80.2 1.5 1.9 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 CAM38105.1 - 1.9e-17 63.8 0.0 3.4e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.15 CAM38105.1 - 3.7e-15 56.1 0.2 7.4e-15 55.1 0.2 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain HGTP_anticodon PF03129.20 CAM38105.1 - 4.3e-15 55.6 0.0 1.5e-14 53.9 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain SET PF00856.28 CAM38106.2 - 3.9e-10 40.4 0.0 7.6e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 SET domain SAF PF08666.12 CAM38106.2 - 0.17 12.6 0.0 43 4.8 0.0 2.9 2 1 0 2 2 2 0 SAF domain CBM_19 PF03427.13 CAM38106.2 - 3.5 7.7 7.7 9.8 6.3 7.7 1.8 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) PIH1 PF08190.12 CAM38107.1 - 6.7e-18 64.7 0.0 6.1e-08 32.3 0.0 3.5 3 0 0 3 3 3 3 PIH1 N-terminal domain PIH1_CS PF18201.1 CAM38107.1 - 5.4e-10 39.6 0.0 3.8e-09 36.9 0.0 2.3 2 0 0 2 2 2 1 PIH1 CS-like domain Phage_Nu1 PF07471.12 CAM38107.1 - 0.29 10.9 6.2 0.85 9.4 6.2 1.8 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 MCRS_N PF13325.6 CAM38108.1 - 0.0035 17.4 0.0 0.0056 16.7 0.0 1.2 1 0 0 1 1 1 1 N-terminal region of micro-spherule protein Myb_DNA-binding PF00249.31 CAM38108.1 - 0.011 15.9 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Mito_carr PF00153.27 CAM38109.1 - 7.5e-33 112.3 5.5 1.2e-12 47.6 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 CAM38110.1 - 3.1e-32 110.4 5.8 5.2e-12 45.5 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Acetyltransf_1 PF00583.25 CAM38111.1 - 5.2e-06 26.7 0.2 0.0015 18.8 0.0 2.7 3 0 0 3 3 3 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CAM38111.1 - 0.0094 16.4 0.1 0.15 12.5 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain MerB PF03243.15 CAM38111.1 - 0.06 13.5 1.0 0.11 12.6 0.3 1.8 2 0 0 2 2 2 0 Alkylmercury lyase Acetyltransf_4 PF13420.7 CAM38111.1 - 0.17 12.0 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Phytochelatin PF05023.14 CAM38112.1 - 0.0014 17.9 0.0 11 5.2 0.0 4.2 4 0 0 4 4 4 3 Phytochelatin synthase DUF1833 PF08875.11 CAM38113.1 - 0.094 12.2 2.4 1.6 8.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1833) HSP70 PF00012.20 CAM38114.1 - 1.7e-108 363.4 7.7 2.4e-103 346.4 0.0 2.8 3 0 0 3 3 3 2 Hsp70 protein FGGY_C PF02782.16 CAM38114.1 - 6.6e-06 26.0 0.9 0.00039 20.2 0.0 2.5 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, C-terminal domain MreB_Mbl PF06723.13 CAM38114.1 - 3.8e-05 22.7 0.0 0.00019 20.4 0.0 2.0 1 1 0 1 1 1 1 MreB/Mbl protein Herpes_U59 PF04529.12 CAM38114.1 - 0.0079 15.3 0.3 1.4 7.9 0.1 2.4 2 0 0 2 2 2 2 Herpesvirus U59 protein E1_dh PF00676.20 CAM38115.1 - 2e-101 338.9 0.1 2.3e-101 338.7 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 CAM38115.1 - 0.012 14.8 0.4 0.039 13.1 0.0 1.8 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase Med14 PF08638.11 CAM38116.1 - 0.044 13.2 0.2 0.077 12.4 0.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit MED14 Ribosomal_L34e PF01199.18 CAM38117.2 - 3e-27 94.7 2.5 3e-27 94.7 2.5 2.2 2 1 0 2 2 2 1 Ribosomal protein L34e RecA PF00154.21 CAM38117.2 - 0.081 12.4 1.9 0.11 12.0 1.9 1.1 1 0 0 1 1 1 0 recA bacterial DNA recombination protein AAA_assoc_C PF09821.9 CAM38117.2 - 3.8 8.1 5.7 5 7.7 5.1 1.5 1 1 0 1 1 1 0 C-terminal AAA-associated domain PUF PF00806.19 CAM38119.1 - 5.6e-46 151.7 0.2 7.3e-06 25.4 0.0 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DnaJ PF00226.31 CAM38120.2 - 5.5e-20 71.2 0.3 1.3e-19 70.1 0.3 1.7 1 0 0 1 1 1 1 DnaJ domain EF-hand_7 PF13499.6 CAM38121.1 - 5.3e-11 42.8 1.6 7.3e-07 29.6 0.9 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CAM38121.1 - 1.7e-09 36.9 1.6 0.00011 21.8 0.1 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 CAM38121.1 - 3.6e-08 32.4 0.9 0.00054 19.3 0.1 3.6 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CAM38121.1 - 5.7e-05 22.9 5.5 0.1 12.4 0.0 3.5 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 CAM38121.1 - 0.0017 17.7 0.7 0.13 11.8 0.1 3.1 3 0 0 3 3 3 1 EF hand DUF3648 PF12364.8 CAM38122.2 - 3.2e-57 192.7 1.2 8.1e-57 191.4 1.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3648) WD40 PF00400.32 CAM38123.1 - 0.004 18.0 0.4 7.9 7.5 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat Mitofilin PF09731.9 CAM38125.1 - 0.97 8.2 27.6 1.1 8.1 27.6 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein NADH-G_4Fe-4S_3 PF10588.9 CAM38126.1 - 1.4e-15 56.5 0.3 1.4e-15 56.5 0.3 2.2 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.6 CAM38126.1 - 1.4e-11 44.3 1.0 1.8e-11 43.9 0.1 1.7 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 CAM38126.1 - 2.9e-07 30.3 0.1 7.7e-07 29.0 0.1 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 CAM38126.1 - 0.1 13.2 6.7 0.22 12.1 3.1 2.9 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 CAM38126.1 - 0.22 11.7 5.5 0.23 11.6 2.4 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 CAM38126.1 - 3.9 7.7 7.3 0.62 10.2 1.1 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain DnaJ PF00226.31 CAM38127.1 - 1.1e-12 47.9 0.0 2.3e-12 46.8 0.0 1.5 1 1 0 1 1 1 1 DnaJ domain zf-CSL PF05207.13 CAM38127.1 - 9.8e-05 22.0 8.0 0.00043 19.9 8.0 2.0 1 1 0 1 1 1 1 CSL zinc finger E1-E2_ATPase PF00122.20 CAM38129.2 - 1.9e-45 154.6 4.7 2.3e-45 154.3 0.7 3.0 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 CAM38129.2 - 1.4e-16 61.4 0.0 4e-16 59.9 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CAM38129.2 - 1.1e-12 47.4 0.0 2.6e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CAM38129.2 - 4.8e-05 23.2 0.0 0.0004 20.2 0.2 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CAM38129.2 - 0.023 14.8 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 Cation transport ATPase (P-type) YrvL PF14184.6 CAM38129.2 - 0.49 10.5 16.6 0.32 11.1 7.7 2.6 2 0 0 2 2 2 0 Regulatory protein YrvL BTB PF00651.31 CAM38132.1 - 1.6e-05 25.1 0.1 4e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 BTB/POZ domain zf-C3HC4_3 PF13920.6 CAM38134.1 - 7.9e-14 51.2 13.5 1e-13 50.9 13.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CAM38134.1 - 6.1e-06 26.0 14.0 9e-06 25.5 14.0 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CAM38134.1 - 0.00033 20.9 16.9 0.0005 20.3 16.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CAM38134.1 - 0.018 14.8 15.9 0.028 14.3 15.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) IU_nuc_hydro PF01156.19 CAM38135.1 - 3.8e-91 305.8 0.3 4.3e-91 305.7 0.3 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Cactin_mid PF10312.9 CAM38135.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Conserved mid region of cactin Kinesin PF00225.23 CAM38137.1 - 3.7e-59 200.3 0.0 8.3e-59 199.2 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CAM38137.1 - 2.4e-07 30.8 0.0 5.9e-07 29.5 0.0 1.6 1 1 0 1 1 1 1 Microtubule binding Noc2 PF03715.13 CAM38138.1 - 5.7e-87 291.7 1.8 5.7e-87 291.7 1.8 1.4 2 0 0 2 2 2 1 Noc2p family PTPA PF03095.15 CAM38138.1 - 0.042 13.3 1.7 5.4 6.4 0.1 2.7 3 0 0 3 3 3 0 Phosphotyrosyl phosphate activator (PTPA) protein YdjC PF04794.12 CAM38138.1 - 0.065 13.2 1.4 0.47 10.4 0.1 2.5 2 0 0 2 2 2 0 YdjC-like protein UPF0242 PF06785.11 CAM38138.1 - 0.099 12.7 0.2 0.099 12.7 0.2 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Got1 PF04178.12 CAM38139.1 - 7e-13 49.0 15.6 8.5e-13 48.7 15.6 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family TPR_1 PF00515.28 CAM38143.1 - 0.011 15.5 0.1 0.1 12.4 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CAM38143.1 - 0.039 14.1 0.7 0.73 10.1 0.0 3.3 4 1 1 5 5 5 0 Tetratricopeptide repeat Coatomer_E PF04733.14 CAM38143.1 - 0.054 12.9 1.0 0.35 10.3 0.1 2.0 1 1 1 2 2 2 0 Coatomer epsilon subunit GCS PF03074.16 CAM38144.1 - 4.4e-141 470.5 0.0 5.7e-141 470.1 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase KRTAP PF11759.8 CAM38146.1 - 1.6e-06 28.5 91.7 1.8e+04 -50.4 91.7 4.4 1 1 0 1 1 1 0 Keratin-associated matrix Keratin_2_head PF16208.5 CAM38146.1 - 0.073 13.2 88.9 1.8e+04 -50.9 88.9 4.7 1 1 0 1 1 1 0 Keratin type II head E1-E2_ATPase PF00122.20 CAM38148.1 - 3.7e-46 156.9 0.7 6.3e-46 156.2 0.7 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 CAM38148.1 - 4.9e-13 48.6 0.0 1e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus YrvL PF14184.6 CAM38148.1 - 0.021 14.9 6.5 0.037 14.1 6.5 1.3 1 0 0 1 1 1 0 Regulatory protein YrvL Cation_ATPase PF13246.6 CAM38148.1 - 0.029 14.4 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 Cation transport ATPase (P-type) DUF2157 PF09925.9 CAM38148.1 - 0.2 11.4 3.6 4.2 7.1 2.7 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) SUR7 PF06687.12 CAM38148.1 - 0.59 9.7 5.9 1.2 8.8 5.9 1.4 1 0 0 1 1 1 0 SUR7/PalI family Claudin_2 PF13903.6 CAM38148.1 - 4.9 6.9 11.2 0.16 11.7 5.1 1.6 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction ACBP PF00887.19 CAM38151.2 - 0.0098 16.1 0.0 0.03 14.6 0.0 1.8 1 0 0 1 1 1 1 Acyl CoA binding protein CDK2AP PF09806.9 CAM38151.2 - 0.75 9.8 7.7 0.66 10.0 1.5 2.6 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein IQ PF00612.27 CAM38152.1 - 0.013 15.3 4.7 2.2 8.3 0.0 3.1 2 0 0 2 2 2 0 IQ calmodulin-binding motif Sec20 PF03908.13 CAM38154.2 - 5.1e-10 39.1 3.9 9e-10 38.3 3.2 1.7 2 0 0 2 2 2 1 Sec20 DASH_Duo1 PF08651.10 CAM38154.2 - 0.13 12.1 0.2 0.31 10.8 0.2 1.6 1 0 0 1 1 1 0 DASH complex subunit Duo1 FlaC_arch PF05377.11 CAM38154.2 - 0.25 11.7 0.6 0.86 10.0 0.5 1.9 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) TFIIF_alpha PF05793.12 CAM38154.2 - 0.82 8.2 2.5 0.99 7.9 2.5 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TMEM247 PF15444.6 CAM38154.2 - 3.1 7.8 4.9 1.5 8.8 0.6 2.1 1 1 0 2 2 2 0 Transmembrane protein 247 TPD52 PF04201.15 CAM38155.2 - 0.087 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Tumour protein D52 family FAD_binding_6 PF00970.24 CAM38157.1 - 8.5e-09 35.7 0.0 4e-08 33.5 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CAM38157.1 - 0.12 13.0 0.0 0.26 12.0 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain PEPCK_ATP PF01293.20 CAM38158.1 - 0.18 10.4 0.0 0.27 9.9 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase Pkinase PF00069.25 CAM38159.1 - 8.3e-45 153.2 0.0 6.8e-32 110.9 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CAM38159.1 - 2e-27 96.1 0.0 8e-21 74.5 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAM38159.1 - 0.00019 20.3 1.1 0.00027 19.9 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CAM38159.1 - 0.001 18.4 0.0 0.21 10.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Proteasome PF00227.26 CAM38160.1 - 5.6e-57 192.3 0.1 7.7e-57 191.9 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CAM38160.1 - 1.9e-14 53.0 0.2 3.6e-14 52.1 0.2 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Styelin PF17562.2 CAM38160.1 - 0.067 13.6 4.6 0.21 12.0 2.8 2.2 2 0 0 2 2 2 0 Styelin Rad51 PF08423.11 CAM38161.1 - 1.4e-18 67.1 0.0 2.9e-18 66.0 0.0 1.6 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 CAM38161.1 - 4.4e-07 29.7 0.4 2e-06 27.5 0.4 2.0 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CAM38161.1 - 2e-06 27.4 0.0 0.038 13.3 0.0 2.1 2 0 0 2 2 2 2 DnaB-like helicase C terminal domain ATPase PF06745.13 CAM38161.1 - 3.2e-06 26.7 0.0 2.6e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 KaiC AAA PF00004.29 CAM38161.1 - 0.00046 20.6 0.0 0.0013 19.1 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RecA PF00154.21 CAM38161.1 - 0.0048 16.4 0.0 0.016 14.7 0.0 1.8 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_16 PF13191.6 CAM38161.1 - 0.022 15.1 0.1 0.05 14.0 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 CAM38161.1 - 0.026 14.7 0.2 0.046 13.9 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CAM38161.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CAM38161.1 - 0.14 12.7 0.0 0.41 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CAM38161.1 - 0.18 12.1 0.9 0.66 10.2 0.9 1.9 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CAM38161.1 - 0.18 11.7 0.0 0.31 10.9 0.0 1.4 1 1 0 1 1 1 0 NTPase Pterin_4a PF01329.19 CAM38162.1 - 3.4e-28 97.6 0.0 4.4e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Pyrophosphatase PF00719.19 CAM38163.1 - 4.3e-45 153.4 0.0 8.4e-45 152.4 0.0 1.5 1 0 0 1 1 1 1 Inorganic pyrophosphatase EF-hand_7 PF13499.6 CAM38163.1 - 0.00013 22.3 0.0 0.00058 20.3 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_9 PF14658.6 CAM38163.1 - 0.085 13.2 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain DUF641 PF04859.12 CAM38164.1 - 0.22 11.9 1.8 4.9 7.5 1.7 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DEAD PF00270.29 CAM38165.1 - 9.8e-23 80.8 0.0 1.6e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CAM38165.1 - 4.6e-07 30.0 0.0 1.3e-06 28.5 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CAM38165.1 - 7.2e-06 26.3 0.1 2.2e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Pre-PUA PF17832.1 CAM38166.1 - 4e-19 69.1 0.2 6e-19 68.5 0.2 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 CAM38166.1 - 5.4e-13 48.7 1.6 9.9e-13 47.9 1.6 1.4 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.10 CAM38166.1 - 0.0097 16.2 0.6 0.26 11.6 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1947) PBSX_XtrA PF17356.2 CAM38166.1 - 0.095 12.6 0.4 15 5.6 0.1 2.3 2 0 0 2 2 2 0 Phage-like element PBSX protein XtrA FumaraseC_C PF10415.9 CAM38166.1 - 0.13 12.7 0.2 0.22 12.0 0.2 1.3 1 0 0 1 1 1 0 Fumarase C C-terminus 3-PAP PF12578.8 CAM38167.1 - 1.4e-14 54.0 2.0 1.4e-14 54.0 2.0 1.9 2 0 0 2 2 2 1 Myotubularin-associated protein Dzip-like_N PF13815.6 CAM38167.1 - 7.9e-06 25.8 1.2 7.9e-06 25.8 1.2 2.9 2 1 1 3 3 3 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal DUF812 PF05667.11 CAM38167.1 - 0.79 8.5 12.2 0.21 10.4 6.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF812) IFT57 PF10498.9 CAM38167.1 - 0.84 8.5 10.3 0.1 11.5 5.7 1.7 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 FapA PF03961.13 CAM38167.1 - 3.4 6.2 4.7 2.9 6.4 3.0 1.7 2 0 0 2 2 2 0 Flagellar Assembly Protein A LMBR1 PF04791.16 CAM38167.1 - 4.2 6.2 4.2 6.9 5.5 4.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein SKA1 PF07160.12 CAM38167.1 - 5 6.9 13.5 1.8 8.4 3.7 3.2 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 1 DUF5595 PF18077.1 CAM38167.1 - 8.3 6.6 6.5 4.9 7.3 1.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5595) DUF3450 PF11932.8 CAM38167.1 - 9.9 5.4 19.0 0.38 10.0 11.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Macoilin PF09726.9 CAM38169.1 - 9.4 4.6 29.2 0.19 10.2 22.5 1.6 2 0 0 2 2 2 0 Macoilin family PSP1 PF04468.12 CAM38170.1 - 8.5e-28 96.5 0.2 1.4e-27 95.7 0.2 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region NIF3 PF01784.18 CAM38171.1 - 2e-67 227.4 0.0 2.4e-67 227.1 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Foamy_virus_ENV PF03408.14 CAM38172.1 - 0.014 13.3 0.1 0.016 13.1 0.1 1.0 1 0 0 1 1 1 0 Foamy virus envelope protein Pkinase PF00069.25 CAM38173.1 - 8.7e-49 166.2 0.0 1.2e-48 165.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM38173.1 - 1.6e-25 89.9 0.0 2.3e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM38173.1 - 4.7e-09 36.0 0.0 1.1e-08 34.7 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 CAM38173.1 - 0.00028 20.9 0.3 0.0013 18.7 0.1 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CAM38173.1 - 0.002 17.1 0.0 0.0033 16.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 CAM38173.1 - 0.0021 17.1 0.1 0.0033 16.6 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 CAM38173.1 - 0.0024 17.2 0.1 0.0048 16.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAC1 PF16094.5 CAM38173.1 - 0.036 13.3 0.0 0.053 12.7 0.0 1.2 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 tRNA-synt_2b PF00587.25 CAM38174.1 - 3.9e-32 111.6 0.0 7.2e-32 110.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 CAM38174.1 - 4.3e-14 52.7 3.5 1.3e-12 47.9 3.5 2.3 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain MORN PF02493.20 CAM38175.1 - 6.6e-32 107.5 46.5 1.8e-06 27.5 0.4 9.8 10 0 0 10 10 10 8 MORN repeat RRM_1 PF00076.22 CAM38176.1 - 8.2e-05 22.4 0.0 0.00019 21.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 CAM38176.1 - 0.25 11.5 6.3 0.15 12.3 0.8 2.1 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter GRIP PF01465.20 CAM38177.2 - 8.1e-11 41.7 0.0 1.8e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 GRIP domain Cep57_CLD_2 PF14197.6 CAM38177.2 - 0.015 15.4 119.5 0.33 11.1 16.0 11.5 8 4 2 10 10 10 0 Centrosome localisation domain of PPC89 DUF575 PF04746.12 CAM38177.2 - 0.1 12.9 8.2 29 5.0 0.1 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF575) Pkinase PF00069.25 CAM38178.1 - 2.3e-41 141.9 0.0 1.6e-26 93.3 0.0 2.7 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM38178.1 - 3.9e-16 59.1 0.4 6.6e-09 35.4 0.2 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase RWD PF05773.22 CAM38178.1 - 1e-05 25.8 0.3 4.7e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 RWD domain APH PF01636.23 CAM38178.1 - 0.0028 17.6 0.0 0.0094 15.9 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 CAM38178.1 - 0.0089 15.7 0.1 0.37 10.4 0.0 2.3 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CAM38178.1 - 0.022 14.1 0.0 0.051 12.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NCD1 PF04904.13 CAM38178.1 - 0.038 14.0 0.1 0.42 10.7 0.0 2.4 2 0 0 2 2 2 0 NAB conserved region 1 (NCD1) PI3K_1B_p101 PF10486.9 CAM38178.1 - 4.2 5.0 12.0 6.4 4.4 12.0 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SNF2_N PF00176.23 CAM38179.1 - 4.3e-25 88.2 0.1 7.8e-25 87.3 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HNH PF01844.23 CAM38179.1 - 6.6e-08 32.6 0.1 6.6e-08 32.6 0.1 2.8 2 0 0 2 2 2 1 HNH endonuclease Helicase_C PF00271.31 CAM38179.1 - 1.5e-05 25.3 0.0 3.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HNH_5 PF14279.6 CAM38179.1 - 0.00081 19.2 0.2 0.00081 19.2 0.2 2.5 3 0 0 3 3 3 1 HNH endonuclease ResIII PF04851.15 CAM38179.1 - 0.014 15.4 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Tenui_NS3 PF05310.12 CAM38179.1 - 0.16 12.1 0.1 0.38 10.8 0.1 1.5 1 0 0 1 1 1 0 Tenuivirus movement protein ABC_tran PF00005.27 CAM38180.1 - 3.2e-27 95.7 0.0 6.3e-27 94.8 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 CAM38180.1 - 3.6e-05 23.7 1.4 0.0053 16.6 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CAM38180.1 - 0.0012 18.4 0.1 0.011 15.2 0.0 2.0 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CAM38180.1 - 0.0065 16.4 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 CAM38180.1 - 0.018 14.7 0.1 0.039 13.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 CAM38180.1 - 0.033 14.6 0.7 0.063 13.7 0.1 1.9 2 1 0 2 2 2 0 AAA ATPase domain KDGP_aldolase PF07071.11 CAM38180.1 - 0.1 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 KDGP aldolase SbcCD_C PF13558.6 CAM38180.1 - 0.21 11.8 3.6 0.46 10.7 0.1 2.9 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit Hexapep PF00132.24 CAM38181.1 - 2.8e-13 49.0 2.8 0.00017 21.2 0.0 3.3 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CAM38181.1 - 0.099 12.4 4.6 7.1 6.5 0.2 3.2 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase COPIIcoated_ERV PF07970.12 CAM38182.1 - 8.1e-34 117.4 0.0 2.3e-33 115.9 0.0 1.6 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CAM38182.1 - 0.00017 21.8 0.0 0.00037 20.8 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF4200 PF13863.6 CAM38183.1 - 0.0091 16.4 16.0 0.59 10.6 10.2 3.1 2 1 1 3 3 3 2 Domain of unknown function (DUF4200) KLRAQ PF10205.9 CAM38183.1 - 0.01 16.1 3.8 0.01 16.1 3.8 2.8 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein ATG16 PF08614.11 CAM38183.1 - 0.024 14.9 15.7 0.06 13.6 14.8 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) SirA PF10747.9 CAM38183.1 - 0.042 14.2 0.1 0.41 11.0 0.0 2.4 2 1 0 2 2 2 0 Sporulation inhibitor of replication protein SirA TMF_TATA_bd PF12325.8 CAM38183.1 - 0.37 11.0 18.4 1.9 8.7 7.8 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding TipAS PF07739.13 CAM38183.1 - 0.38 11.3 2.6 8.9 6.9 0.6 3.2 3 1 0 3 3 3 0 TipAS antibiotic-recognition domain PRKG1_interact PF15898.5 CAM38183.1 - 0.62 11.0 18.3 0.072 14.0 9.3 2.5 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF724 PF05266.14 CAM38183.1 - 0.81 9.5 11.0 3.3 7.5 4.8 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF724) TRAF_BIRC3_bd PF16673.5 CAM38183.1 - 1.9 8.3 9.0 2.4 8.0 3.0 3.0 3 1 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain Plk4_PB2 PF18409.1 CAM38183.1 - 2.6 8.8 4.8 3.6 8.3 0.1 2.9 1 1 2 3 3 3 0 Polo-like Kinase 4 Polo Box 2 CENP-H PF05837.12 CAM38183.1 - 3.4 8.1 14.5 0.97 9.9 6.8 2.7 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Shugoshin_N PF07558.11 CAM38183.1 - 4.9 7.1 7.7 4.7 7.2 1.1 3.4 2 1 1 3 3 3 0 Shugoshin N-terminal coiled-coil region HIP1_clath_bdg PF16515.5 CAM38183.1 - 7.2 7.3 18.2 8.7 7.0 0.1 3.7 1 1 3 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4407 PF14362.6 CAM38183.1 - 7.3 5.9 8.9 15 4.9 8.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Csm1_N PF18504.1 CAM38183.1 - 8.9 6.7 15.0 0.54 10.6 0.5 3.5 2 1 2 4 4 4 0 Csm1 N-terminal domain DUF2239 PF09998.9 CAM38184.1 - 0.002 18.0 2.2 0.0024 17.7 0.3 2.1 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2239) Use1 PF09753.9 CAM38184.1 - 0.034 13.9 17.8 0.02 14.6 12.2 2.6 1 1 1 2 2 2 0 Membrane fusion protein Use1 XhlA PF10779.9 CAM38184.1 - 0.1 12.8 3.0 1.1 9.5 0.0 3.1 2 1 0 2 2 2 0 Haemolysin XhlA DUF5113 PF17140.4 CAM38184.1 - 0.13 12.1 0.2 0.26 11.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5113) Syntaxin-6_N PF09177.11 CAM38184.1 - 0.33 11.5 7.2 0.27 11.8 0.9 2.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF1676 PF07898.13 CAM38184.1 - 0.35 10.9 0.0 0.35 10.9 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1676) DUF1759 PF03564.15 CAM38184.1 - 0.56 10.1 3.7 2.7 7.9 0.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1759) TBCC_N PF16752.5 CAM38184.1 - 0.72 10.3 13.5 0.072 13.5 4.3 3.3 2 2 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain DUF948 PF06103.11 CAM38184.1 - 1.4 9.2 6.9 2.5 8.4 0.2 3.1 3 1 0 3 3 2 0 Bacterial protein of unknown function (DUF948) KIP1 PF07765.12 CAM38184.1 - 1.9 8.7 5.1 1.3 9.2 1.3 2.6 2 0 0 2 2 2 0 KIP1-like protein SNARE PF05739.19 CAM38184.1 - 2 8.5 6.7 1.8 8.6 2.5 3.1 3 1 0 3 3 3 0 SNARE domain Rx_N PF18052.1 CAM38184.1 - 2.7 8.3 7.6 17 5.7 1.2 3.1 3 0 0 3 3 2 0 Rx N-terminal domain Agouti PF05039.12 CAM38184.1 - 2.9 8.7 5.4 1.9 9.2 1.2 2.7 2 1 0 2 2 2 0 Agouti protein CK2S PF15011.6 CAM38184.1 - 4.6 7.1 12.1 0.77 9.6 1.7 3.0 2 1 1 3 3 3 0 Casein Kinase 2 substrate NPA PF16469.5 CAM38184.1 - 5.5 7.6 8.8 0.25 11.9 2.3 2.1 3 0 0 3 3 2 0 Nematode polyprotein allergen ABA-1 TPR_MLP1_2 PF07926.12 CAM38184.1 - 7.4 6.7 15.6 5.7 7.0 5.7 3.1 2 2 0 2 2 2 0 TPR/MLP1/MLP2-like protein Histone PF00125.24 CAM38186.1 - 7.6e-12 45.7 1.4 1.1e-11 45.3 1.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CAM38186.1 - 0.0004 20.6 0.3 0.00075 19.7 0.3 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CAM38187.2 - 7.6e-12 45.7 1.4 1.1e-11 45.3 1.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CAM38187.2 - 0.00039 20.6 0.3 0.00075 19.7 0.3 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CAM38188.1 - 4e-12 46.6 1.7 5.3e-12 46.2 1.7 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CAM38188.1 - 0.00012 22.3 0.3 0.00025 21.3 0.3 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ribosomal_S5_C PF03719.15 CAM38189.1 - 4.8e-25 86.8 0.0 8e-25 86.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 CAM38189.1 - 6.5e-23 80.5 0.8 1.3e-22 79.5 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain FoP_duplication PF13865.6 CAM38189.1 - 0.084 13.4 7.7 0.2 12.2 7.7 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Phage_tail_NK PF16532.5 CAM38189.1 - 0.21 11.2 0.0 0.34 10.5 0.0 1.2 1 0 0 1 1 1 0 Sf6-type phage tail needle knob or tip of some Caudovirales SH3_9 PF14604.6 CAM38190.1 - 9.2e-09 35.0 0.0 1.7e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CAM38190.1 - 3.2e-07 29.9 0.0 6e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CAM38190.1 - 3.9e-05 23.2 0.0 9e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain DUF1772 PF08592.11 CAM38190.1 - 0.071 13.4 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) DnaJ PF00226.31 CAM38191.1 - 1.9e-19 69.5 0.5 8.8e-19 67.4 0.5 2.3 1 0 0 1 1 1 1 DnaJ domain DUF865 PF05906.11 CAM38191.1 - 0.02 14.7 0.4 0.037 13.8 0.4 1.4 1 0 0 1 1 1 0 Herpesvirus-7 repeat of unknown function (DUF865) HydF_tetramer PF18133.1 CAM38192.2 - 0.11 12.3 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Hydrogen maturase F tetramerization domain CAMSAP_CC1 PF17095.5 CAM38192.2 - 0.17 11.8 0.3 0.17 11.8 0.3 3.6 5 0 0 5 5 5 0 Spectrin-binding region of Ca2+-Calmodulin DnaJ PF00226.31 CAM38192.2 - 4.6 7.4 8.2 2.3 8.4 0.8 3.1 3 1 0 3 3 3 0 DnaJ domain Fibrillarin PF01269.17 CAM38193.1 - 5.9e-99 329.8 0.0 7.1e-99 329.5 0.0 1.1 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 CAM38193.1 - 2e-06 27.7 0.0 3e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltr_RsmB-F PF01189.17 CAM38193.1 - 0.012 15.2 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Lar_N PF09861.9 CAM38193.1 - 0.23 10.6 0.0 0.4 9.8 0.0 1.3 1 0 0 1 1 1 0 Lactate racemase N-terminal domain Clathrin_lg_ch PF01086.17 CAM38194.1 - 6.8e-11 42.7 0.1 7.5e-11 42.5 0.1 1.1 1 0 0 1 1 1 1 Clathrin light chain Globin PF00042.22 CAM38194.1 - 0.088 13.4 0.7 0.13 12.8 0.7 1.2 1 0 0 1 1 1 0 Globin mRNA_cap_C PF03919.15 CAM38194.1 - 0.1 13.3 0.3 0.13 12.9 0.3 1.2 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain PRCC PF10253.9 CAM38194.1 - 1.8 9.3 11.4 2.5 8.9 11.4 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SNARE PF05739.19 CAM38195.1 - 4.8e-09 36.1 4.0 7.1e-09 35.5 2.6 2.1 2 1 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 CAM38195.1 - 0.056 13.8 8.1 0.13 12.7 0.2 2.6 2 1 0 2 2 2 0 Syntaxin-like protein Laminin_II PF06009.12 CAM38195.1 - 0.061 13.3 4.8 0.76 9.8 0.6 2.9 2 1 1 3 3 3 0 Laminin Domain II UPF0242 PF06785.11 CAM38195.1 - 2.3 8.3 12.1 3.7 7.6 12.1 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DER1 PF04511.15 CAM38196.1 - 1.3e-33 116.5 8.1 1.5e-33 116.3 8.1 1.0 1 0 0 1 1 1 1 Der1-like family Pkinase PF00069.25 CAM38197.1 - 5.3e-49 167.0 0.0 9.1e-49 166.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM38197.1 - 1e-24 87.2 0.0 6.3e-20 71.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase CAP_GLY PF01302.25 CAM38197.1 - 3.5e-16 59.0 0.5 7.2e-16 58.0 0.5 1.5 1 0 0 1 1 1 1 CAP-Gly domain Kinase-like PF14531.6 CAM38197.1 - 9.2e-05 21.9 0.0 0.032 13.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase PF00069.25 CAM38198.1 - 8.8e-58 195.7 0.0 1e-57 195.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM38198.1 - 2.9e-34 118.6 0.0 3.4e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAM38198.1 - 2.5e-05 23.2 0.0 3.6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase ABC1 PF03109.16 CAM38198.1 - 0.0056 16.8 0.0 0.015 15.5 0.0 1.6 1 1 0 1 1 1 1 ABC1 family UPF0258 PF06789.12 CAM38198.1 - 0.15 12.1 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) Kinase-like PF14531.6 CAM38198.1 - 0.19 11.0 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Peptidase_M24 PF00557.24 CAM38199.1 - 1.4e-21 77.2 0.6 1.9e-21 76.8 0.6 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Pkinase PF00069.25 CAM38201.1 - 4.8e-71 239.2 0.0 5.9e-71 238.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM38201.1 - 9.9e-31 107.0 0.1 3.3e-30 105.2 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CAM38201.1 - 0.019 14.9 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family MYO10_CC PF16735.5 CAM38201.1 - 1.1 9.4 6.1 10 6.3 0.1 2.4 2 0 0 2 2 2 0 Unconventional myosin-X coiled coil domain HTH_3 PF01381.22 CAM38202.1 - 1.6e-11 44.0 0.2 2.7e-11 43.4 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix MBF1 PF08523.10 CAM38202.1 - 7.4e-11 42.3 5.5 7.4e-11 42.3 5.5 1.6 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_31 PF13560.6 CAM38202.1 - 0.0011 19.3 0.6 0.002 18.4 0.6 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 CAM38202.1 - 0.0022 17.9 0.1 0.0042 17.1 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.6 CAM38202.1 - 0.0088 16.6 0.8 0.0088 16.6 0.8 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_37 PF13744.6 CAM38202.1 - 0.029 14.3 0.3 0.063 13.2 0.3 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain MqsA_antitoxin PF15731.5 CAM38202.1 - 0.038 14.1 0.4 0.057 13.5 0.4 1.4 1 1 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA Mito_carr PF00153.27 CAM38203.1 - 8e-68 224.4 4.5 2.2e-24 85.2 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 CAM38203.1 - 0.0049 16.1 0.2 0.0086 15.3 0.2 1.3 1 0 0 1 1 1 1 Fuseless Mito_carr PF00153.27 CAM38204.1 - 8e-68 224.4 4.5 2.2e-24 85.2 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 CAM38204.1 - 0.0049 16.1 0.2 0.0086 15.3 0.2 1.3 1 0 0 1 1 1 1 Fuseless polyprenyl_synt PF00348.17 CAM38205.1 - 3.1e-52 177.2 0.0 4.2e-52 176.7 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase CrtC PF07143.11 CAM38205.1 - 8.8e-16 59.0 0.0 9.3e-15 55.7 0.0 2.1 1 1 0 1 1 1 1 CrtC N-terminal lipocalin domain Lipocalin_9 PF17186.4 CAM38205.1 - 6.4e-12 45.9 0.0 1.1e-11 45.2 0.0 1.3 1 0 0 1 1 1 1 Lipocalin-like domain CDK5_activator PF03261.15 CAM38205.1 - 0.018 14.6 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Complex1_LYR PF05347.15 CAM38206.1 - 4e-07 30.0 0.7 4.3e-06 26.7 0.0 3.0 3 0 0 3 3 3 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CAM38206.1 - 0.008 16.9 0.5 0.008 16.9 0.5 3.0 3 1 1 4 4 4 1 Complex1_LYR-like GN3L_Grn1 PF08701.11 CAM38207.1 - 0.00019 21.4 15.6 0.00049 20.1 15.6 1.7 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase UVR PF02151.19 CAM38208.1 - 1.4e-08 34.2 15.0 0.00032 20.3 7.0 2.6 2 0 0 2 2 2 2 UvrB/uvrC motif zf-Di19 PF05605.12 CAM38208.1 - 0.0018 18.5 3.0 0.0018 18.5 3.0 2.8 2 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding HEAT_EZ PF13513.6 CAM38208.1 - 0.0039 17.6 2.5 0.83 10.2 0.1 3.5 2 1 1 3 3 3 1 HEAT-like repeat HEAT PF02985.22 CAM38208.1 - 0.1 12.9 1.1 3.8 8.0 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat zf-C2H2_4 PF13894.6 CAM38208.1 - 2.4 9.2 14.7 1.9 9.6 0.2 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger Kinesin PF00225.23 CAM38209.1 - 4.7e-102 341.3 0.5 1.3e-101 339.9 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CAM38209.1 - 6.3e-45 152.8 0.1 4.7e-44 149.9 0.0 2.5 2 0 0 2 2 2 1 Microtubule binding Dor1 PF04124.12 CAM38209.1 - 1e-05 24.4 0.8 1.9e-05 23.5 0.8 1.3 1 0 0 1 1 1 1 Dor1-like family VHS PF00790.19 CAM38209.1 - 2.5e-05 24.1 1.2 9.6e-05 22.3 0.0 2.5 3 0 0 3 3 2 1 VHS domain Macoilin PF09726.9 CAM38209.1 - 0.012 14.2 4.8 0.022 13.4 4.8 1.4 1 0 0 1 1 1 0 Macoilin family SRA1 PF07304.11 CAM38209.1 - 0.049 13.4 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) Atg14 PF10186.9 CAM38209.1 - 0.078 12.0 9.6 0.18 10.9 6.3 2.4 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 CAM38209.1 - 0.098 12.0 10.7 0.16 11.3 5.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Tup_N PF08581.10 CAM38209.1 - 0.2 12.0 10.8 0.47 10.8 6.2 2.7 2 0 0 2 2 2 0 Tup N-terminal CDC45 PF02724.14 CAM38209.1 - 0.29 9.4 8.1 0.47 8.7 8.1 1.2 1 0 0 1 1 1 0 CDC45-like protein TPR_MLP1_2 PF07926.12 CAM38209.1 - 0.79 9.8 19.0 1.3 9.1 11.8 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein CCDC84 PF14968.6 CAM38209.1 - 1.8 8.1 10.4 0.16 11.6 0.1 3.2 4 0 0 4 4 4 0 Coiled coil protein 84 CENP-H PF05837.12 CAM38209.1 - 3.4 8.1 16.6 7.1 7.1 4.1 3.6 3 0 0 3 3 3 0 Centromere protein H (CENP-H) Spc24 PF08286.11 CAM38209.1 - 4.1 7.7 7.3 20 5.5 7.3 2.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 YkyA PF10368.9 CAM38209.1 - 7.1 6.3 15.6 0.11 12.1 4.1 3.1 3 0 0 3 3 3 0 Putative cell-wall binding lipoprotein GAS PF13851.6 CAM38209.1 - 7.7 5.8 17.7 3.2 7.1 13.5 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Metal_resist PF13801.6 CAM38209.1 - 8.8 6.5 14.1 1.3 9.2 8.3 2.3 2 0 0 2 2 2 0 Heavy-metal resistance DUF5600 PF18150.1 CAM38211.1 - 1.8e-17 63.8 0.1 4.8e-17 62.5 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) Dynamin_N PF00350.23 CAM38211.1 - 2.7e-14 53.6 0.0 9.3e-13 48.6 0.0 2.4 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 CAM38211.1 - 2.4e-07 30.8 0.0 5.8e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EHD_N PF16880.5 CAM38211.1 - 0.00019 21.2 0.8 0.00052 19.8 0.4 1.9 2 0 0 2 2 2 1 N-terminal EH-domain containing protein AAA_25 PF13481.6 CAM38211.1 - 0.022 14.3 0.0 0.092 12.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CAM38211.1 - 0.11 12.4 0.0 9.1 6.2 0.0 2.7 3 0 0 3 3 3 0 RsgA GTPase AAA_22 PF13401.6 CAM38211.1 - 0.19 12.0 0.0 11 6.3 0.0 3.1 4 0 0 4 4 4 0 AAA domain cobW PF02492.19 CAM38211.1 - 0.21 11.2 0.0 10 5.7 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain U-box PF04564.15 CAM38213.1 - 0.0029 17.7 0.0 0.008 16.3 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 CAM38213.1 - 0.015 15.4 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf_CCCH_4 PF18345.1 CAM38213.1 - 0.79 9.9 8.9 0.52 10.4 1.9 2.4 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH PF00642.24 CAM38214.1 - 0.00059 19.7 6.1 0.0038 17.1 1.0 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) U-box PF04564.15 CAM38214.1 - 0.0065 16.6 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 CAM38214.1 - 0.022 14.9 0.0 0.048 13.8 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein CorA PF01544.18 CAM38214.1 - 0.25 10.6 3.0 0.36 10.1 3.0 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein zf_CCCH_4 PF18345.1 CAM38214.1 - 1.3 9.2 8.0 0.11 12.6 2.7 2.1 2 0 0 2 2 2 0 Zinc finger domain Cep57_CLD_2 PF14197.6 CAM38214.1 - 1.5 9.0 6.4 7.9 6.6 6.4 2.0 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 UPF0016 PF01169.19 CAM38215.1 - 3.1e-43 146.0 20.3 4.3e-22 78.2 4.1 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 ABC_transp_aux PF09822.9 CAM38216.1 - 2.2e-06 27.4 0.0 3.8e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 ABC-type uncharacterized transport system DUF4350 PF14258.6 CAM38216.1 - 0.0015 18.9 0.0 0.0064 16.9 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4350) WD40 PF00400.32 CAM38217.2 - 2.4e-08 34.5 21.6 0.0089 16.9 0.1 6.0 7 0 0 7 7 7 3 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 CAM38217.2 - 0.0026 16.9 0.0 0.0091 15.1 0.0 1.9 2 0 0 2 2 2 1 Coatomer WD associated region ANAPC4_WD40 PF12894.7 CAM38217.2 - 0.006 16.9 0.3 20 5.6 0.0 5.3 3 1 3 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain DUF1143 PF06608.11 CAM38218.1 - 0.00052 20.1 1.5 0.026 14.6 1.5 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1143) Radical_SAM PF04055.21 CAM38219.2 - 1.2e-11 45.3 0.1 1.8e-11 44.7 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily LIAS_N PF16881.5 CAM38219.2 - 2.6e-09 37.5 0.0 7.2e-09 36.0 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Pkinase PF00069.25 CAM38220.2 - 7.4e-26 91.1 0.0 2.3e-14 53.4 0.0 3.8 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM38220.2 - 3.7e-08 33.0 0.1 0.0021 17.4 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase RIO1 PF01163.22 CAM38220.2 - 0.014 15.0 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 RIO1 family WD40 PF00400.32 CAM38222.2 - 1.1e-09 38.7 2.6 0.00034 21.3 0.1 5.9 5 0 0 5 5 5 2 WD domain, G-beta repeat PDZ_2 PF13180.6 CAM38222.2 - 0.00013 22.2 0.0 0.00032 21.0 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CAM38222.2 - 0.005 16.6 0.1 0.016 15.0 0.1 1.8 1 0 0 1 1 1 1 PDZ domain ANAPC4_WD40 PF12894.7 CAM38222.2 - 0.062 13.6 0.1 3.3 8.1 0.1 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 CAM38222.2 - 7.2 7.2 9.6 20 5.8 0.0 4.4 4 0 0 4 4 4 0 PQQ-like domain Ribosomal_S13_N PF08069.12 CAM38223.1 - 8.4e-25 86.6 1.8 1.6e-24 85.7 1.8 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 CAM38223.1 - 1.9e-13 50.4 1.1 3.2e-13 49.7 1.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 Synaptobrevin PF00957.21 CAM38224.1 - 4.8e-11 42.3 0.0 9.4e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CAM38224.1 - 0.069 13.2 0.0 0.2 11.7 0.0 1.7 2 0 0 2 2 2 0 Regulated-SNARE-like domain UMP1 PF05348.11 CAM38225.1 - 5.9e-05 23.3 0.0 7.2e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 TFIIS_C PF01096.18 CAM38226.1 - 2.8e-18 65.5 2.5 2.8e-18 65.5 2.5 2.4 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 CAM38226.1 - 8.4e-06 25.6 3.0 0.00022 21.0 0.7 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 CAM38226.1 - 0.00023 21.0 2.3 0.36 10.9 0.2 2.4 2 0 0 2 2 2 2 Transposase zinc-ribbon domain Baculo_LEF5_C PF11792.8 CAM38226.1 - 0.0078 15.9 0.1 0.022 14.4 0.1 1.8 1 0 0 1 1 1 1 Baculoviridae late expression factor 5 C-terminal domain B_solenoid_ydck PF18836.1 CAM38226.1 - 0.12 12.3 0.4 0.28 11.1 0.4 1.6 1 0 0 1 1 1 0 Beta solenoid repeat from YDCK zinc_ribbon_10 PF10058.9 CAM38226.1 - 0.53 10.1 4.1 9.9 6.0 0.1 3.2 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein NAP PF00956.18 CAM38228.1 - 1.3e-57 195.1 0.3 1.3e-57 195.1 0.3 1.7 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) BSP_II PF05432.11 CAM38228.1 - 0.0018 18.1 3.7 0.0018 18.1 3.7 2.0 3 0 0 3 3 3 1 Bone sialoprotein II (BSP-II) MgtE_N PF03448.17 CAM38228.1 - 0.0023 18.5 0.5 0.0062 17.1 0.5 1.8 1 0 0 1 1 1 1 MgtE intracellular N domain PGA2 PF07543.12 CAM38228.1 - 0.0065 16.5 2.3 0.0065 16.5 2.3 2.5 3 0 0 3 3 3 1 Protein trafficking PGA2 DpnI_C PF17726.1 CAM38228.1 - 0.07 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Dam-replacing HTH domain Uso1_p115_C PF04871.13 CAM38229.1 - 0.087 13.2 0.7 0.17 12.2 0.7 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region CCDC53 PF10152.9 CAM38230.1 - 5.1e-46 156.9 0.0 6.4e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex UPF0193 PF05250.11 CAM38234.1 - 0.00099 19.0 1.1 0.0018 18.1 1.1 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0193) PilJ PF13675.6 CAM38234.1 - 0.025 14.6 2.8 0.035 14.1 0.7 2.3 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term P22_CoatProtein PF11651.8 CAM38234.1 - 0.23 10.0 0.0 0.34 9.5 0.0 1.1 1 0 0 1 1 1 0 P22 coat protein - gene protein 5 SAP PF02037.27 CAM38235.2 - 0.1 12.4 0.0 0.6 9.9 0.0 2.3 2 0 0 2 2 2 0 SAP domain LRR_8 PF13855.6 CAM38237.2 - 7.4e-07 28.8 0.7 0.025 14.3 0.0 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CAM38237.2 - 6.3e-06 26.4 0.2 0.099 13.1 0.0 3.6 2 1 4 6 6 6 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CAM38237.2 - 0.0017 17.9 0.0 0.059 12.9 0.0 2.2 1 1 1 2 2 2 2 Leucine-rich repeat Peptidase_M24 PF00557.24 CAM38238.1 - 1.2e-47 162.4 0.1 1.7e-47 161.9 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 CAM38238.1 - 1e-14 54.5 8.4 2.2e-14 53.4 8.4 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 CAM38238.1 - 1.8e-05 24.8 5.6 3.7e-05 23.7 5.6 1.6 1 0 0 1 1 1 1 MYND finger TBCC PF07986.12 CAM38239.2 - 2.3e-23 82.2 14.2 1.1e-08 34.8 0.0 3.4 3 0 0 3 3 3 3 Tubulin binding cofactor C CAP_C PF08603.11 CAM38239.2 - 0.92 9.1 3.9 0.29 10.8 0.5 1.8 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) C terminal CCP_MauG PF03150.14 CAM38240.2 - 0.24 12.0 1.8 2.1 9.0 0.1 2.8 2 0 0 2 2 2 0 Di-haem cytochrome c peroxidase CH_2 PF06294.11 CAM38241.1 - 7.9e-19 67.6 0.0 1.7e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 CH-like domain in sperm protein EI24 PF07264.11 CAM38242.1 - 2.9 8.1 13.6 1.8 8.8 1.5 2.7 3 0 0 3 3 3 0 Etoposide-induced protein 2.4 (EI24) Pkinase PF00069.25 CAM38243.1 - 6.5e-44 150.3 0.0 5.8e-33 114.4 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CAM38243.1 - 1.4e-14 54.0 0.0 2.3e-13 50.0 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase DAG1 PF05454.11 CAM38245.1 - 0.00043 19.8 1.0 0.00047 19.6 1.0 1.1 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF4118 PF13493.6 CAM38245.1 - 0.0061 16.3 3.3 0.0081 15.9 3.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4118) Mid2 PF04478.12 CAM38245.1 - 0.015 15.2 0.2 0.018 14.9 0.2 1.1 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF5493 PF17597.2 CAM38245.1 - 0.079 13.2 0.2 0.13 12.5 0.2 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5493) Protocadherin PF08374.11 CAM38245.1 - 0.46 10.4 1.6 0.56 10.1 1.6 1.0 1 0 0 1 1 1 0 Protocadherin CYTH PF01928.21 CAM38246.1 - 3.5e-13 49.9 0.3 4.3e-05 23.5 0.0 3.8 4 0 0 4 4 4 2 CYTH domain Histone PF00125.24 CAM38247.1 - 2.3e-38 131.5 5.0 2.8e-38 131.3 5.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CAM38247.1 - 2.3e-07 31.0 2.5 3e-07 30.6 0.1 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 CAM38247.1 - 1.6e-05 25.0 1.7 2e-05 24.6 0.1 1.8 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold MIP-T3 PF10243.9 CAM38247.1 - 0.11 12.4 0.1 0.4 10.7 0.0 1.8 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 CH-like domain ANF_receptor PF01094.28 CAM38248.1 - 2.3e-37 128.9 7.6 1.9e-28 99.6 1.9 2.9 2 1 0 2 2 2 2 Receptor family ligand binding region Peripla_BP_6 PF13458.6 CAM38248.1 - 1.3e-08 34.9 9.0 5.3e-06 26.3 2.6 2.8 2 1 0 2 2 2 2 Periplasmic binding protein Glucodextran_C PF09985.9 CAM38248.1 - 0.013 15.0 0.0 0.8 9.1 0.0 2.3 2 0 0 2 2 2 0 C-terminal binding-module, SLH-like, of glucodextranase RNA_pol_A_bac PF01000.26 CAM38250.1 - 1.2e-19 70.7 0.0 2.4e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CAM38250.1 - 8.5e-15 53.9 0.0 1.2e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_9 PF13187.6 CAM38250.1 - 0.0061 16.7 0.4 0.014 15.6 0.4 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain ETF_QO PF05187.13 CAM38250.1 - 0.03 14.5 0.4 0.42 10.8 0.1 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_7 PF12838.7 CAM38250.1 - 0.071 13.7 1.7 0.078 13.6 0.4 1.8 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_10 PF13237.6 CAM38250.1 - 0.11 12.6 1.5 0.22 11.7 0.9 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 CAM38250.1 - 0.96 9.6 2.6 2.1 8.6 0.9 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Utp11 PF03998.13 CAM38251.1 - 7.2e-30 104.7 36.6 1e-27 97.7 36.6 2.1 1 1 0 1 1 1 1 Utp11 protein DUF3718 PF12514.8 CAM38251.1 - 0.4 10.9 1.8 6.6 7.0 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3718) Kinesin PF00225.23 CAM38252.1 - 1.7e-92 309.9 0.3 7.9e-92 307.7 0.0 2.3 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CAM38252.1 - 4.9e-15 55.8 0.0 6.8e-10 39.1 0.0 3.1 3 0 0 3 3 3 2 Microtubule binding DUF1510 PF07423.11 CAM38252.1 - 0.24 11.5 0.8 0.81 9.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1510) DUF4347 PF14252.6 CAM38252.1 - 1.4 8.8 4.1 0.85 9.5 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4347) Kinesin PF00225.23 CAM38253.2 - 4.1e-93 311.9 10.7 1.5e-76 257.5 0.4 4.8 4 0 0 4 4 4 3 Kinesin motor domain Microtub_bd PF16796.5 CAM38253.2 - 7.8e-14 51.9 6.4 1.2e-08 35.0 0.0 4.8 5 0 0 5 5 5 2 Microtubule binding Kinesin_assoc PF16183.5 CAM38253.2 - 0.00011 22.4 8.5 0.00011 22.4 8.5 10.2 3 3 4 7 7 7 1 Kinesin-associated Pox_A_type_inc PF04508.12 CAM38253.2 - 0.00039 20.1 5.8 0.57 10.1 0.3 6.6 7 0 0 7 7 7 1 Viral A-type inclusion protein repeat FR47 PF08445.10 CAM38253.2 - 0.11 12.5 0.4 0.42 10.6 0.4 2.0 1 0 0 1 1 1 0 FR47-like protein Pedibin PF08182.11 CAM38253.2 - 0.67 9.8 5.3 10 6.0 0.2 3.9 3 0 0 3 3 3 0 Pedibin/Hym-346 family Formin_GBD_N PF18382.1 CAM38253.2 - 1.2 9.7 6.2 0.97 9.9 0.9 3.8 2 0 0 2 2 2 0 Formin N-terminal GTPase-binding domain DUF4988 PF16378.5 CAM38253.2 - 4.2 7.0 7.3 4.2 7.0 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function Ldh_1_C PF02866.18 CAM38254.1 - 1.1e-35 123.1 0.0 1.6e-35 122.5 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 CAM38254.1 - 2e-35 121.9 0.2 3.1e-35 121.3 0.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 CAM38254.1 - 0.0055 15.7 0.0 0.058 12.4 0.0 2.0 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1664 PF07889.12 CAM38255.1 - 1.1e-05 25.4 13.3 0.032 14.3 1.2 3.5 1 1 3 4 4 4 2 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 CAM38255.1 - 2e-05 24.7 10.9 0.15 12.1 1.0 3.5 1 1 2 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_MLP1_2 PF07926.12 CAM38255.1 - 3.3e-05 24.0 16.7 3.4e-05 23.9 1.8 3.5 2 1 2 4 4 4 1 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 CAM38255.1 - 0.00025 20.0 16.0 0.053 12.4 0.3 2.3 1 1 2 3 3 3 3 Spc7 kinetochore protein GAS PF13851.6 CAM38255.1 - 0.00029 20.2 6.0 0.00029 20.2 6.0 2.6 1 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 CAM38255.1 - 0.00049 20.6 18.7 0.0079 16.7 11.6 2.5 1 1 1 2 2 2 1 Fez1 DUF948 PF06103.11 CAM38255.1 - 0.0017 18.6 8.8 0.69 10.2 0.1 4.3 2 1 1 3 3 3 1 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 CAM38255.1 - 0.0017 18.6 6.9 1.7 8.9 0.2 3.5 2 1 1 3 3 3 2 Fibrinogen alpha/beta chain family IFT57 PF10498.9 CAM38255.1 - 0.0021 17.1 9.3 0.01 14.8 4.3 2.3 1 1 1 2 2 2 1 Intra-flagellar transport protein 57 ThiD2 PF17792.1 CAM38255.1 - 0.0076 16.7 14.0 0.053 14.0 7.2 2.4 1 1 1 2 2 2 1 ThiD2 family Laminin_II PF06009.12 CAM38255.1 - 0.0078 16.2 12.8 0.022 14.8 0.5 3.6 2 1 2 4 4 4 1 Laminin Domain II Leu_zip PF15294.6 CAM38255.1 - 0.008 15.7 9.7 0.015 14.8 0.9 2.9 1 1 2 3 3 3 1 Leucine zipper AKNA PF12443.8 CAM38255.1 - 0.011 16.4 1.3 0.043 14.5 0.6 2.4 1 1 1 2 2 1 0 AT-hook-containing transcription factor BAR_3 PF16746.5 CAM38255.1 - 0.011 15.4 5.3 0.44 10.2 0.0 2.5 1 1 1 2 2 2 0 BAR domain of APPL family Alanine_zipper PF11839.8 CAM38255.1 - 0.016 15.6 6.7 0.016 15.6 6.7 3.4 4 0 0 4 4 2 0 Alanine-zipper, major outer membrane lipoprotein Tektin PF03148.14 CAM38255.1 - 0.016 14.0 14.5 0.27 9.9 0.1 3.1 1 1 0 2 2 2 0 Tektin family ApoLp-III PF07464.11 CAM38255.1 - 0.019 15.0 3.2 0.099 12.7 0.2 2.8 1 1 2 3 3 3 0 Apolipophorin-III precursor (apoLp-III) BLOC1_2 PF10046.9 CAM38255.1 - 0.02 15.2 9.1 6.9 7.1 0.6 4.7 2 1 3 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LOH1CR12 PF10158.9 CAM38255.1 - 0.029 14.4 3.7 0.72 9.9 0.1 3.1 1 1 1 3 3 3 0 Tumour suppressor protein RmuC PF02646.16 CAM38255.1 - 0.048 12.8 11.8 0.099 11.8 0.4 3.5 1 1 1 3 3 3 0 RmuC family CorA PF01544.18 CAM38255.1 - 0.062 12.6 11.7 1.3 8.2 5.1 2.5 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Bacillus_HBL PF05791.11 CAM38255.1 - 0.078 12.8 5.8 1 9.1 1.2 3.0 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Peptidase_M32 PF02074.15 CAM38255.1 - 0.08 11.7 3.6 0.11 11.2 3.6 1.3 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase SepF PF04472.12 CAM38255.1 - 0.08 13.2 0.5 1.9 8.8 0.1 2.7 2 1 0 2 2 2 0 Cell division protein SepF Collagen_mid PF15984.5 CAM38255.1 - 0.1 12.3 0.0 0.31 10.8 0.0 1.7 1 1 0 1 1 1 0 Bacterial collagen, middle region betaPIX_CC PF16523.5 CAM38255.1 - 0.11 12.3 5.4 0.42 10.5 1.6 3.2 2 1 0 2 2 2 0 betaPIX coiled coil V_ATPase_I PF01496.19 CAM38255.1 - 0.11 10.4 7.3 0.067 11.1 5.5 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Prefoldin_2 PF01920.20 CAM38255.1 - 0.13 12.3 11.6 0.77 9.7 2.1 4.0 2 2 2 4 4 4 0 Prefoldin subunit Tropomyosin_1 PF12718.7 CAM38255.1 - 0.13 12.4 17.2 2.2 8.4 12.2 3.2 1 1 2 3 3 3 0 Tropomyosin like TMP_2 PF06791.13 CAM38255.1 - 0.13 11.9 3.9 0.062 13.0 0.6 2.0 2 0 0 2 2 2 0 Prophage tail length tape measure protein Exonuc_VII_L PF02601.15 CAM38255.1 - 0.14 11.7 16.5 37 3.7 16.5 2.2 1 1 0 1 1 1 0 Exonuclease VII, large subunit COG2 PF06148.11 CAM38255.1 - 0.15 12.2 15.1 5.1 7.2 0.2 4.1 1 1 3 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1043 PF06295.12 CAM38255.1 - 0.15 12.0 7.4 1.1 9.2 0.2 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF1043) Atg14 PF10186.9 CAM38255.1 - 0.16 11.0 11.1 0.95 8.5 9.9 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Syntaxin_2 PF14523.6 CAM38255.1 - 0.18 12.2 15.0 1.6 9.2 2.2 3.5 2 2 0 2 2 2 0 Syntaxin-like protein FAM76 PF16046.5 CAM38255.1 - 0.21 10.9 8.8 1.4 8.3 4.0 2.3 1 1 1 2 2 2 0 FAM76 protein ZYG-11_interact PF05884.12 CAM38255.1 - 0.22 10.9 2.0 0.33 10.3 0.6 1.9 1 1 1 2 2 2 0 Interactor of ZYG-11 TMF_TATA_bd PF12325.8 CAM38255.1 - 0.24 11.6 18.3 0.15 12.3 6.4 3.5 2 2 1 3 3 3 0 TATA element modulatory factor 1 TATA binding TMPIT PF07851.13 CAM38255.1 - 0.28 10.4 7.6 1.8 7.8 0.9 2.9 1 1 2 3 3 3 0 TMPIT-like protein DUF4795 PF16043.5 CAM38255.1 - 0.29 10.7 16.1 0.89 9.1 8.2 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Syntaxin-6_N PF09177.11 CAM38255.1 - 0.31 11.6 11.3 5.5e+02 1.2 11.3 3.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal PhaP_Bmeg PF09602.10 CAM38255.1 - 0.38 10.7 5.2 0.38 10.7 1.2 2.6 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Phage_GPO PF05929.11 CAM38255.1 - 0.42 10.2 13.8 1.3 8.6 1.6 2.6 1 1 2 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase Prominin PF05478.11 CAM38255.1 - 0.43 8.5 4.1 0.89 7.4 3.9 1.6 1 1 0 1 1 1 0 Prominin CREPT PF16566.5 CAM38255.1 - 0.46 10.6 12.5 0.36 11.0 2.9 3.3 1 1 2 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour DUF2721 PF11026.8 CAM38255.1 - 0.55 10.1 15.1 1.6 8.6 0.1 4.2 2 1 2 4 4 4 0 Protein of unknown function (DUF2721) DUF5340 PF17275.2 CAM38255.1 - 0.57 10.3 3.4 0.84 9.8 0.2 2.6 3 0 0 3 3 2 0 Family of unknown function (DUF5340) FadA PF09403.10 CAM38255.1 - 0.62 10.6 10.0 1.3 9.5 2.3 3.6 2 1 1 3 3 3 0 Adhesion protein FadA HlyD_2 PF12700.7 CAM38255.1 - 0.65 8.7 2.2 0.47 9.1 0.6 1.5 2 0 0 2 2 2 0 HlyD family secretion protein DUF745 PF05335.13 CAM38255.1 - 0.71 9.6 18.6 0.16 11.6 5.1 3.7 1 1 3 4 4 4 0 Protein of unknown function (DUF745) AAA_27 PF13514.6 CAM38255.1 - 0.74 9.4 11.5 0.14 11.8 0.8 3.1 1 1 2 3 3 3 0 AAA domain zf-C4H2 PF10146.9 CAM38255.1 - 0.85 9.9 11.6 4.3 7.6 8.1 2.3 1 1 1 2 2 2 0 Zinc finger-containing protein FH2 PF02181.23 CAM38255.1 - 1.3 8.1 5.5 3.9 6.5 4.2 2.4 1 1 0 1 1 1 0 Formin Homology 2 Domain GCN5L1 PF06320.13 CAM38255.1 - 1.3 9.2 10.5 25 5.1 0.2 3.6 1 1 4 5 5 5 0 GCN5-like protein 1 (GCN5L1) DUF4407 PF14362.6 CAM38255.1 - 1.7 7.9 22.8 1.5 8.1 4.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Ran-binding PF05508.11 CAM38255.1 - 2 7.3 6.9 0.33 9.9 0.9 2.5 1 1 1 3 3 3 0 RanGTP-binding protein Seryl_tRNA_N PF02403.22 CAM38255.1 - 2.2 8.6 15.2 31 4.8 7.3 3.7 2 1 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain YabA PF06156.13 CAM38255.1 - 2.3 8.9 9.6 27 5.5 0.2 3.2 2 2 0 2 2 2 0 Initiation control protein YabA DUF724 PF05266.14 CAM38255.1 - 2.7 7.8 11.4 2.7 7.8 0.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF2730 PF10805.8 CAM38255.1 - 3.1 8.0 4.9 4.7 7.4 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) DUF3347 PF11827.8 CAM38255.1 - 3.2 7.9 7.0 1.5 9.0 1.0 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF3347) APG6_N PF17675.1 CAM38255.1 - 3.3 8.3 19.8 2.2 8.8 5.2 3.3 2 1 1 3 3 3 0 Apg6 coiled-coil region PhageMin_Tail PF10145.9 CAM38255.1 - 4.2 7.2 8.7 91 2.8 8.8 3.1 1 1 0 1 1 1 0 Phage-related minor tail protein Methyltransf_11 PF08241.12 CAM38256.1 - 5e-12 46.3 0.0 1.1e-11 45.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAM38256.1 - 3.7e-11 43.6 0.0 7.2e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAM38256.1 - 5e-11 43.2 0.0 9.3e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAM38256.1 - 1.7e-06 27.9 0.0 3.3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAM38256.1 - 1.8e-05 24.6 0.0 3.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CAM38256.1 - 0.00093 18.6 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 CAM38256.1 - 0.0013 18.7 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Vps36_ESCRT-II PF11605.8 CAM38257.1 - 9.4e-25 86.6 0.0 1.6e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 EAP30 PF04157.16 CAM38257.1 - 5.8e-22 78.1 0.0 8.1e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Ribosomal_S25 PF03297.15 CAM38257.1 - 0.008 16.4 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 S25 ribosomal protein IRS PF02174.17 CAM38257.1 - 0.046 13.6 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 PTB domain (IRS-1 type) PhnJ PF06007.11 CAM38257.1 - 0.062 12.3 0.0 0.096 11.7 0.0 1.2 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnJ Rsm22 PF09243.10 CAM38258.2 - 0.0096 15.2 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Mem_trans PF03547.18 CAM38259.1 - 1.1e-21 76.7 8.1 6.4e-21 74.2 8.1 2.1 1 1 0 1 1 1 1 Membrane transport protein DUF2062 PF09835.9 CAM38259.1 - 0.0049 16.7 0.4 0.0049 16.7 0.4 2.8 3 0 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2062) V-SNARE_C PF12352.8 CAM38260.1 - 1.2e-10 41.5 3.4 1.2e-10 41.5 3.4 2.7 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 CAM38260.1 - 3.4e-06 26.9 1.3 7.9e-06 25.7 0.0 2.2 3 0 0 3 3 3 1 Sec20 DUF572 PF04502.13 CAM38260.1 - 0.024 14.3 3.0 1 8.9 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF5082 PF16888.5 CAM38260.1 - 0.064 13.5 2.1 3.8 7.8 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) PLU-1 PF08429.11 CAM38260.1 - 0.066 12.4 1.9 1.6 7.8 0.4 2.1 2 0 0 2 2 2 0 PLU-1-like protein UPF0029 PF01205.19 CAM38260.1 - 0.086 13.2 0.2 0.18 12.2 0.2 1.6 1 1 0 1 1 1 0 Uncharacterized protein family UPF0029 Prefoldin PF02996.17 CAM38260.1 - 0.13 12.1 5.7 3.5 7.6 0.1 2.7 2 1 0 2 2 2 0 Prefoldin subunit Fib_alpha PF08702.10 CAM38260.1 - 0.52 10.5 2.9 0.54 10.4 1.1 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family ATG16 PF08614.11 CAM38260.1 - 4 7.6 16.2 2.1 8.6 13.0 1.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) RasGAP_C PF03836.15 CAM38260.1 - 5 7.3 9.7 11 6.2 6.4 2.5 2 1 1 3 3 3 0 RasGAP C-terminus SRP_TPR_like PF17004.5 CAM38262.1 - 2.2e-11 43.8 4.8 2.2e-11 43.8 4.8 3.0 3 1 0 3 3 3 1 Putative TPR-like repeat SRP72 PF08492.12 CAM38262.1 - 1.2e-07 32.1 0.8 1.2e-07 32.1 0.8 2.9 2 0 0 2 2 2 1 SRP72 RNA-binding domain ANAPC3 PF12895.7 CAM38262.1 - 3.3e-06 27.2 19.7 3.5e-05 24.0 8.0 5.0 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 CAM38262.1 - 0.013 16.0 43.1 0.58 10.7 2.2 8.0 5 2 3 9 9 9 0 Tetratricopeptide repeat TPR_2 PF07719.17 CAM38262.1 - 0.053 13.7 22.5 2.5 8.4 0.3 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 CAM38262.1 - 0.068 13.8 21.5 5.6 7.8 0.1 7.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 CAM38262.1 - 0.13 12.7 9.7 44 4.8 0.1 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 CAM38262.1 - 0.22 11.9 11.7 6.8 7.2 0.8 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 CAM38262.1 - 0.27 11.9 0.1 0.27 11.9 0.1 7.9 7 2 2 9 9 9 0 Tetratricopeptide repeat TPR_7 PF13176.6 CAM38262.1 - 3.1 8.0 13.4 2.4 8.4 2.0 5.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CAM38262.1 - 6.1 6.8 13.9 16 5.5 0.4 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat ABC_tran PF00005.27 CAM38263.1 - 5.4e-42 143.5 0.0 2.6e-20 73.4 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 CAM38263.1 - 2.3e-23 82.0 5.5 5.7e-22 77.5 2.3 2.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 CAM38263.1 - 1.8e-21 77.3 0.3 1.2e-05 25.3 0.0 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CAM38263.1 - 2.6e-11 43.4 1.4 0.0026 17.2 0.0 4.4 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 CAM38263.1 - 1.7e-07 31.5 0.0 0.045 13.9 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.6 CAM38263.1 - 2.6e-07 31.0 0.0 0.0093 16.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 CAM38263.1 - 4e-07 30.8 5.9 0.032 14.8 0.0 3.6 4 0 0 4 4 3 2 AAA domain AAA_16 PF13191.6 CAM38263.1 - 1.1e-06 29.2 0.0 0.0087 16.5 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 CAM38263.1 - 1.6e-06 28.6 0.0 0.0084 16.5 0.0 3.1 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CAM38263.1 - 3.8e-06 27.2 0.1 0.017 15.5 0.0 3.3 3 0 0 3 3 3 1 RNA helicase AAA_18 PF13238.6 CAM38263.1 - 4.2e-06 27.3 0.0 0.062 13.8 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 CAM38263.1 - 1.2e-05 25.0 0.0 0.22 11.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CAM38263.1 - 2.8e-05 24.4 0.2 0.034 14.4 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 CAM38263.1 - 3.5e-05 23.7 4.7 0.41 10.3 0.0 3.9 4 0 0 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 CAM38263.1 - 4e-05 23.6 0.1 0.04 13.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 CAM38263.1 - 4.1e-05 23.5 0.0 0.26 11.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase TsaE PF02367.17 CAM38263.1 - 8.9e-05 22.5 0.1 0.005 16.8 0.0 2.9 2 1 1 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 CAM38263.1 - 0.0001 22.2 0.1 0.19 11.7 0.0 2.8 3 0 0 3 3 3 1 NACHT domain AAA_14 PF13173.6 CAM38263.1 - 0.00011 22.2 0.0 2.3 8.3 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA_25 PF13481.6 CAM38263.1 - 0.00019 21.1 0.0 0.58 9.7 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_24 PF13479.6 CAM38263.1 - 0.00019 21.2 0.0 0.088 12.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 CAM38263.1 - 0.00048 19.7 0.0 0.11 12.0 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 CAM38263.1 - 0.00081 19.4 0.0 1.3 9.1 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Rad17 PF03215.15 CAM38263.1 - 0.00083 19.3 0.1 0.37 10.7 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain NB-ARC PF00931.22 CAM38263.1 - 0.0015 17.7 0.0 0.64 9.2 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_30 PF13604.6 CAM38263.1 - 0.0017 18.1 0.1 0.87 9.3 0.0 3.2 3 1 0 3 3 2 1 AAA domain AAA_13 PF13166.6 CAM38263.1 - 0.0022 16.8 0.1 2.3 6.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain PduV-EutP PF10662.9 CAM38263.1 - 0.0026 17.5 0.0 0.55 10.0 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation dNK PF01712.19 CAM38263.1 - 0.0087 15.9 0.0 0.51 10.2 0.0 2.4 2 0 0 2 2 2 1 Deoxynucleoside kinase Mg_chelatase PF01078.21 CAM38263.1 - 0.011 15.1 0.0 4.2 6.7 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Roc PF08477.13 CAM38263.1 - 0.023 14.9 0.0 1.3 9.3 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RuvB_N PF05496.12 CAM38263.1 - 0.025 14.3 0.1 0.29 10.9 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain cobW PF02492.19 CAM38263.1 - 0.026 14.1 0.2 2.5 7.7 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 CAM38263.1 - 0.027 14.2 0.0 2.6 7.8 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 CAM38263.1 - 0.032 13.5 0.0 0.62 9.3 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_27 PF13514.6 CAM38263.1 - 0.035 13.7 0.0 17 5.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.22 CAM38263.1 - 0.04 13.5 0.2 0.78 9.3 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 CAM38263.1 - 0.042 13.8 0.1 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 NTPase ATPase_2 PF01637.18 CAM38263.1 - 0.05 13.5 0.0 6.3 6.6 0.0 2.6 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea MeaB PF03308.16 CAM38263.1 - 0.089 11.8 0.6 1.8 7.5 0.0 2.5 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB KapB PF08810.10 CAM38263.1 - 0.098 12.8 1.0 0.24 11.6 0.0 2.0 2 0 0 2 2 2 0 Kinase associated protein B ATP-synt_ab PF00006.25 CAM38263.1 - 0.15 11.7 0.0 9.6 5.8 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain HSBP1 PF06825.12 CAM38263.1 - 0.48 10.3 0.1 0.48 10.3 0.1 2.0 2 0 0 2 2 1 0 Heat shock factor binding protein 1 Vps53_N PF04100.12 CAM38264.2 - 2.3e-66 224.3 10.9 3.2e-66 223.8 10.9 1.2 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF1664 PF07889.12 CAM38264.2 - 0.062 13.3 0.5 0.25 11.4 0.5 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) SNARE PF05739.19 CAM38264.2 - 0.24 11.4 2.1 0.68 10.0 1.3 2.2 1 1 1 2 2 2 0 SNARE domain XhlA PF10779.9 CAM38264.2 - 0.41 10.9 3.6 0.59 10.4 0.3 2.8 1 1 2 3 3 3 0 Haemolysin XhlA Atg8 PF02991.16 CAM38266.1 - 5.3e-11 42.6 0.0 7.2e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Kinesin PF00225.23 CAM38267.2 - 2.4e-71 240.4 0.0 2.4e-71 240.4 0.0 2.2 2 1 0 2 2 2 1 Kinesin motor domain FliJ PF02050.16 CAM38267.2 - 0.019 15.2 2.0 0.019 15.2 2.0 6.5 4 1 3 7 7 7 0 Flagellar FliJ protein Nucleoporin_FG2 PF15967.5 CAM38267.2 - 0.046 12.3 0.4 0.11 11.0 0.4 1.6 1 0 0 1 1 1 0 Nucleoporin FG repeated region ATG16 PF08614.11 CAM38267.2 - 0.1 12.8 0.3 0.1 12.8 0.3 5.6 3 1 1 5 5 5 0 Autophagy protein 16 (ATG16) Kinesin PF00225.23 CAM38268.2 - 3.8e-10 39.2 0.1 1.3e-09 37.5 0.1 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CAM38268.2 - 8.6e-06 25.8 0.1 0.00015 21.7 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding Atg8 PF02991.16 CAM38269.1 - 1.5e-09 37.9 0.0 2.1e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG5 PF04106.12 CAM38269.1 - 0.0032 17.1 0.0 0.0032 17.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 Atg8 PF02991.16 CAM38270.2 - 1.9e-09 37.6 0.0 2.6e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG5 PF04106.12 CAM38270.2 - 0.0056 16.3 0.0 0.0056 16.3 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 CAP_GLY PF01302.25 CAM38272.1 - 9e-18 64.1 0.2 1.6e-17 63.3 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain DUF1878 PF08963.10 CAM38272.1 - 0.28 11.7 6.0 0.18 12.3 1.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1878) FlaC_arch PF05377.11 CAM38272.1 - 2.8 8.4 12.3 34 4.9 0.5 4.8 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) ABC_tran_CTD PF16326.5 CAM38273.2 - 0.084 13.1 0.9 0.33 11.2 0.6 2.2 1 1 0 1 1 1 0 ABC transporter C-terminal domain Anti-adapt_IraP PF10796.9 CAM38273.2 - 0.13 12.9 0.1 6 7.5 0.0 2.6 2 0 0 2 2 2 0 Sigma-S stabilisation anti-adaptor protein DUF4407 PF14362.6 CAM38273.2 - 4 6.7 7.2 5.8 6.2 4.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Dynein_light PF01221.18 CAM38274.1 - 1.2e-26 92.8 0.8 1.4e-26 92.6 0.8 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 FKBP_C PF00254.28 CAM38275.1 - 7.8e-11 42.2 0.0 1.2e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Ank_2 PF12796.7 CAM38276.1 - 1.6e-28 99.1 14.2 3.2e-07 30.8 0.0 10.0 9 1 1 10 10 10 5 Ankyrin repeats (3 copies) Ank PF00023.30 CAM38276.1 - 4.9e-16 58.4 16.7 0.00064 20.1 0.2 11.3 12 0 0 12 12 12 3 Ankyrin repeat Ank_3 PF13606.6 CAM38276.1 - 1.7e-14 52.5 22.8 0.0031 17.9 0.1 14.3 15 0 0 15 15 15 3 Ankyrin repeat Ank_4 PF13637.6 CAM38276.1 - 1.7e-14 53.9 4.8 0.14 12.8 0.1 10.1 9 0 0 9 9 9 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CAM38276.1 - 2.8e-10 40.2 15.1 0.12 12.8 0.0 10.0 10 1 1 11 11 11 4 Ankyrin repeats (many copies) FYVE PF01363.21 CAM38278.1 - 5.1e-14 52.2 5.5 5.1e-14 52.2 5.5 2.3 2 1 0 2 2 2 1 FYVE zinc finger AMP-binding PF00501.28 CAM38280.1 - 1e-81 274.7 0.2 1.2e-81 274.5 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CAM38280.1 - 1.1e-10 42.3 0.0 2.8e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain WD40 PF00400.32 CAM38281.1 - 1.8e-15 57.0 3.1 0.00018 22.2 0.4 7.3 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM38281.1 - 0.013 15.8 0.0 26 5.2 0.0 3.6 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 CAM38281.1 - 0.019 14.2 0.0 2.5 7.3 0.0 2.7 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Nup160 PF11715.8 CAM38281.1 - 0.028 13.1 0.1 0.45 9.1 0.0 2.4 2 0 0 2 2 2 0 Nucleoporin Nup120/160 eIF2A PF08662.11 CAM38281.1 - 0.06 13.2 0.0 0.71 9.7 0.0 2.3 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A PseudoU_synth_1 PF01416.20 CAM38282.1 - 5.4e-15 55.8 0.0 3.6e-13 49.9 0.0 2.6 2 0 0 2 2 2 2 tRNA pseudouridine synthase Cir_N PF10197.9 CAM38283.2 - 0.017 15.3 3.7 0.017 15.3 3.7 4.1 3 2 1 4 4 4 0 N-terminal domain of CBF1 interacting co-repressor CIR tRNA_synthFbeta PF17759.1 CAM38284.1 - 7e-40 136.7 0.0 1.1e-39 136.2 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 CAM38284.1 - 6.5e-30 103.2 0.3 2.6e-29 101.3 0.1 2.0 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B5 PF03484.15 CAM38284.1 - 5.4e-20 71.5 0.1 6.5e-15 55.2 0.1 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain B3_4 PF03483.17 CAM38284.1 - 5.8e-17 61.9 0.0 9.6e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain CENP-X PF09415.10 CAM38286.2 - 0.18 12.2 2.1 0.62 10.4 0.1 2.9 2 0 0 2 2 2 0 CENP-S associating Centromere protein X DUF4795 PF16043.5 CAM38286.2 - 3.8 7.1 11.5 2.4 7.7 0.2 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4795) IcmF-related PF06761.12 CAM38287.1 - 0.0012 18.4 1.4 0.0016 18.0 1.4 1.3 1 0 0 1 1 1 1 Intracellular multiplication and human macrophage-killing Thioredoxin PF00085.20 CAM38287.1 - 0.038 14.0 0.1 0.14 12.2 0.1 1.9 1 1 0 1 1 1 0 Thioredoxin Castor1_N PF18700.1 CAM38287.1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain Fcf1 PF04900.12 CAM38288.1 - 4.2e-31 107.3 2.5 7.4e-31 106.5 2.5 1.4 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 CAM38288.1 - 6.5e-13 49.0 0.0 1.1e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 PIN like domain Actin PF00022.19 CAM38289.1 - 3.7e-74 249.8 0.0 4.3e-74 249.6 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CAM38289.1 - 0.11 11.3 0.0 8.6 5.1 0.0 2.3 2 0 0 2 2 2 0 MreB/Mbl protein CHCH PF06747.13 CAM38290.1 - 4.5e-05 23.4 0.8 8.4e-05 22.6 0.8 1.5 1 1 0 1 1 1 1 CHCH domain NDUF_B7 PF05676.13 CAM38290.1 - 0.013 15.2 2.3 0.023 14.4 2.3 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 CAM38290.1 - 0.017 15.1 1.0 0.031 14.3 1.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.13 CAM38290.1 - 0.054 13.8 2.8 0.59 10.5 0.8 2.3 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Mod_r PF07200.13 CAM38292.1 - 4 7.5 10.9 0.7 10.0 5.6 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein SPX PF03105.19 CAM38293.1 - 0.016 15.2 8.2 0.023 14.6 8.2 1.2 1 0 0 1 1 1 0 SPX domain E2F_CC-MB PF16421.5 CAM38293.1 - 0.067 13.6 0.0 0.067 13.6 0.0 2.4 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain Merozoite_SPAM PF07133.11 CAM38293.1 - 0.28 11.1 23.0 0.015 15.3 16.2 2.0 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) DDE_Tnp_4 PF13359.6 CAM38293.1 - 0.31 10.7 1.0 1.3 8.6 0.1 2.1 2 0 0 2 2 2 0 DDE superfamily endonuclease Cwf_Cwc_15 PF04889.12 CAM38293.1 - 5.8 6.6 29.0 0.2 11.3 21.5 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Mto2_bdg PF12808.7 CAM38294.2 - 0.23 11.8 3.6 0.14 12.5 0.5 2.3 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Mito_carr PF00153.27 CAM38295.1 - 3.6e-51 171.1 3.8 4.4e-17 61.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PCI PF01399.27 CAM38296.1 - 6e-08 33.1 0.0 2.1e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 PCI domain DUF3947 PF13135.6 CAM38298.1 - 0.14 12.3 3.1 0.6 10.3 3.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) SUIM_assoc PF16619.5 CAM38298.1 - 0.95 9.6 5.7 0.6 10.2 0.6 3.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Tape_meas_lam_C PF09718.10 CAM38298.1 - 3.3 7.9 5.7 1.8 8.8 0.0 3.0 3 0 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Pex2_Pex12 PF04757.14 CAM38299.1 - 2.6e-35 122.0 0.1 6.4e-35 120.8 0.1 1.6 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 CAM38299.1 - 0.0087 15.9 4.6 0.019 14.8 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CAM38299.1 - 0.017 15.4 1.9 0.032 14.6 1.9 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 CAM38299.1 - 0.13 12.2 1.7 0.27 11.1 1.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NMD3 PF04981.13 CAM38300.1 - 0.079 12.4 0.4 0.12 11.8 0.4 1.2 1 0 0 1 1 1 0 NMD3 family zf-Mss51 PF13824.6 CAM38300.1 - 0.12 12.5 0.1 0.24 11.6 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf_C2H2_13 PF18508.1 CAM38300.1 - 1 9.0 3.8 14 5.4 0.1 2.2 1 1 1 2 2 2 0 Zinc finger domain Surp PF01805.20 CAM38301.1 - 2.5e-13 49.8 0.6 2.5e-13 49.8 0.6 2.0 3 0 0 3 3 3 1 Surp module Band_7 PF01145.25 CAM38302.1 - 2.2e-28 99.4 0.1 5.2e-28 98.2 0.0 1.6 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 CAM38302.1 - 0.0073 16.0 0.1 0.019 14.6 0.1 1.8 1 1 0 1 1 1 1 SPFH domain-Band 7 family MBOAT PF03062.19 CAM38303.1 - 2.2e-29 102.9 17.7 2.2e-29 102.9 17.7 2.9 2 1 0 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family MBOAT PF03062.19 CAM38304.1 - 1.1e-29 103.9 19.0 1.1e-29 103.9 19.0 2.8 2 1 0 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family MBOAT PF03062.19 CAM38305.1 - 1.1e-16 61.1 9.4 1.1e-16 61.1 9.4 2.1 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family SH3_4 PF06347.13 CAM38306.1 - 0.12 12.2 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain MBOAT PF03062.19 CAM38307.1 - 8.3e-29 101.0 18.2 1.5e-28 100.2 18.2 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT PF03062.19 CAM38308.1 - 2.8e-29 102.6 19.8 2.8e-29 102.6 19.8 2.8 2 1 0 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family MBOAT PF03062.19 CAM38310.1 - 9e-29 100.9 17.1 9e-29 100.9 17.1 2.2 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT PF03062.19 CAM38311.1 - 2.4e-30 106.1 14.9 2.4e-30 106.1 14.9 2.3 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family PAP2 PF01569.21 CAM38313.1 - 2.4e-25 88.9 3.1 2.4e-25 88.9 3.1 2.1 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 CAM38313.1 - 0.0096 15.6 1.4 0.0096 15.6 1.4 2.6 2 2 0 3 3 3 1 PAP2 superfamily DUF2417 PF10329.9 CAM38314.1 - 0.0084 15.6 0.7 0.0084 15.6 0.7 1.8 1 1 1 2 2 2 1 Region of unknown function (DUF2417) DUF898 PF05987.13 CAM38314.1 - 0.057 12.5 1.1 0.065 12.3 1.1 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF3566 PF12089.8 CAM38314.1 - 0.078 13.3 3.2 0.094 13.1 3.2 1.1 1 0 0 1 1 1 0 Transmembrane domain of unknown function (DUF3566) DUF2207 PF09972.9 CAM38314.1 - 0.12 11.1 2.3 0.23 10.2 2.2 1.2 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Sar8_2 PF03058.14 CAM38314.1 - 0.58 10.7 4.6 0.93 10.1 4.6 1.4 1 1 0 1 1 1 0 Sar8.2 family TMEM154 PF15102.6 CAM38314.1 - 0.74 9.7 3.9 0.56 10.1 0.4 1.9 1 1 1 2 2 2 0 TMEM154 protein family Sigma_reg_N PF13800.6 CAM38314.1 - 1.4 9.2 5.2 0.39 11.0 1.0 1.9 1 1 1 2 2 2 0 Sigma factor regulator N-terminal DUF2721 PF11026.8 CAM38314.1 - 3 7.7 9.0 4 7.3 2.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) DUF1067 PF06362.11 CAM38315.1 - 0.15 12.9 0.2 0.53 11.1 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1067) PDZ_6 PF17820.1 CAM38316.1 - 2.3e-06 27.4 0.0 5.2e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CAM38316.1 - 0.00065 20.0 0.0 0.0023 18.2 0.0 2.0 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 CAM38316.1 - 0.002 18.4 0.0 0.0043 17.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain DUF641 PF04859.12 CAM38316.1 - 0.0029 17.9 0.0 0.0092 16.3 0.0 1.8 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) Cation_efflux PF01545.21 CAM38317.1 - 2.5e-32 112.2 8.0 1.7e-19 70.3 2.9 2.2 2 0 0 2 2 2 2 Cation efflux family TBP PF00352.21 CAM38318.1 - 8.3e-42 141.0 0.1 1.1e-23 83.0 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) TPR_11 PF13414.6 CAM38319.1 - 5.9e-10 38.7 0.1 0.01 15.5 0.1 4.4 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.17 CAM38319.1 - 9.1e-09 34.8 7.8 0.00034 20.5 0.0 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 CAM38319.1 - 1.6e-07 31.2 0.6 0.024 15.0 0.0 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CAM38319.1 - 4.4e-07 29.5 4.9 0.0016 18.2 0.0 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 CAM38319.1 - 5.6e-07 29.3 2.9 0.0077 16.4 0.0 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 CAM38319.1 - 0.00017 21.8 0.5 0.016 15.5 0.4 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CAM38319.1 - 0.0002 21.9 0.1 0.64 11.0 0.0 4.2 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 CAM38319.1 - 0.0055 17.3 0.0 0.76 10.5 0.0 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 CAM38319.1 - 0.012 15.4 0.0 0.14 12.1 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 CAM38319.1 - 0.022 15.3 0.1 35 5.0 0.0 3.6 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 CAM38319.1 - 0.029 14.1 0.1 0.045 13.5 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 CAM38319.1 - 0.041 14.5 2.3 8.3 7.3 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat Sel1 PF08238.12 CAM38319.1 - 0.078 13.7 0.6 41 5.0 0.0 3.6 4 0 0 4 4 3 0 Sel1 repeat TPR_7 PF13176.6 CAM38319.1 - 0.17 12.0 1.5 0.4 10.8 0.4 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat PAP_assoc PF03828.19 CAM38320.1 - 2e-12 47.1 0.0 1e-11 44.9 0.1 2.2 2 0 0 2 2 2 1 Cid1 family poly A polymerase Peptidase_C1 PF00112.23 CAM38321.1 - 3e-68 230.2 6.1 4.7e-68 229.5 6.1 1.3 1 0 0 1 1 1 1 Papain family cysteine protease DUF3586 PF12131.8 CAM38321.1 - 3.5e-28 97.7 8.3 9.7e-28 96.2 8.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3586) Inhibitor_I29 PF08246.12 CAM38321.1 - 4.7e-09 36.5 0.7 7.8e-09 35.8 0.7 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CAM38321.1 - 0.0051 15.7 4.0 0.034 12.9 0.2 2.6 3 0 0 3 3 3 2 Peptidase C1-like family DUF4880 PF16220.5 CAM38321.1 - 0.072 13.0 0.4 12 5.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4880) PIH1 PF08190.12 CAM38322.1 - 5.6e-05 22.7 0.0 0.00011 21.7 0.0 1.4 1 0 0 1 1 1 1 PIH1 N-terminal domain PIH1_CS PF18201.1 CAM38322.1 - 0.00095 19.5 0.1 0.0027 18.1 0.0 1.7 2 0 0 2 2 2 1 PIH1 CS-like domain Pkinase PF00069.25 CAM38323.1 - 8.6e-67 225.3 0.0 1e-66 225.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM38323.1 - 6.4e-34 117.4 0.0 9.1e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM38323.1 - 2.6e-06 27.0 0.0 3.7e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CAM38323.1 - 0.0013 18.7 0.1 0.0024 17.8 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CAM38323.1 - 0.02 14.3 0.5 0.038 13.4 0.5 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CAM38323.1 - 0.086 11.8 0.0 0.19 10.6 0.0 1.3 1 1 0 1 1 1 0 Haspin like kinase domain Oxidored-like PF09791.9 CAM38324.1 - 1.4e-11 43.9 1.4 3.6e-11 42.6 1.4 1.7 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal NAD_binding_1 PF00175.21 CAM38324.1 - 2.8e-11 44.0 0.0 4.7e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.20 CAM38324.1 - 0.00014 21.5 0.0 0.0086 15.7 0.0 2.4 2 0 0 2 2 2 1 FAD binding domain NAD_binding_6 PF08030.12 CAM38324.1 - 0.14 12.3 0.1 23 5.1 0.0 2.3 2 0 0 2 2 2 0 Ferric reductase NAD binding domain DUF5522 PF17653.1 CAM38324.1 - 0.22 11.5 3.4 0.56 10.2 3.4 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5522) COX6B PF02297.17 CAM38325.1 - 0.1 12.8 1.8 0.17 12.1 1.8 1.5 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb Pkinase PF00069.25 CAM38326.1 - 1.3e-43 149.3 0.0 1.1e-29 103.6 0.0 3.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM38326.1 - 7.7e-18 64.7 0.0 8e-15 54.8 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAM38326.1 - 0.094 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase IF4E PF01652.18 CAM38327.1 - 1.4e-39 135.5 0.0 2.1e-39 134.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E TPT PF03151.16 CAM38329.1 - 6.8e-20 71.6 18.9 7.9e-20 71.4 18.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CAM38329.1 - 0.00035 20.7 11.1 0.00035 20.7 11.1 2.5 1 1 0 2 2 2 1 EamA-like transporter family FKBP_C PF00254.28 CAM38331.1 - 4.3e-32 110.3 0.0 5.2e-31 106.8 0.0 2.5 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 CAM38331.1 - 1.5e-07 31.0 0.0 0.022 14.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CAM38331.1 - 3.5e-07 30.6 0.4 2.3e-06 28.0 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 CAM38331.1 - 6.3e-07 29.0 0.1 0.016 15.3 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CAM38331.1 - 1.6e-05 24.9 0.0 4.7e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 CAM38331.1 - 0.00011 22.4 0.2 0.035 14.4 0.0 3.1 1 1 1 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CAM38331.1 - 0.0034 17.6 0.0 0.01 16.1 0.0 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CAM38331.1 - 0.007 16.3 0.1 0.62 10.2 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CAM38331.1 - 0.0071 17.1 0.4 0.62 11.0 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CAM38331.1 - 0.0082 16.3 0.0 15 6.1 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 CAM38331.1 - 0.05 14.0 0.2 21 5.8 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat FKBP_N_2 PF18023.1 CAM38331.1 - 0.05 13.7 0.0 2.6 8.2 0.0 2.5 2 1 0 2 2 2 0 BDBT FKBP like N-terminal TPR_10 PF13374.6 CAM38331.1 - 0.077 12.9 0.3 8 6.5 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Carn_acyltransf PF00755.20 CAM38332.1 - 4e-143 478.2 0.0 5.4e-143 477.7 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase WD40 PF00400.32 CAM38333.1 - 7e-10 39.3 3.3 0.00091 20.0 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM38333.1 - 1.9e-07 31.3 0.0 0.00019 21.6 0.0 3.5 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 CAM38333.1 - 0.16 11.2 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus IMPDH PF00478.25 CAM38334.1 - 6.5e-123 410.1 5.1 8e-123 409.8 5.1 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 CAM38334.1 - 3.9e-12 46.4 0.5 1.9e-05 25.0 0.0 2.6 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 CAM38334.1 - 9.8e-11 41.3 0.2 9.8e-11 41.3 0.2 1.6 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 CAM38334.1 - 6.3e-05 22.5 3.6 0.084 12.2 2.7 2.4 2 1 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 CAM38334.1 - 0.028 13.9 0.2 0.85 9.0 0.0 2.4 1 1 1 2 2 2 0 Histidine biosynthesis protein ELMO_CED12 PF04727.13 CAM38335.1 - 9e-28 97.6 0.0 1.4e-27 96.9 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family Peptidase_M41 PF01434.18 CAM38337.1 - 1.1e-42 146.0 0.2 1.8e-42 145.3 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CAM38337.1 - 6.3e-41 139.9 0.1 1.5e-39 135.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAM38337.1 - 6.5e-05 22.7 0.1 0.00038 20.2 0.1 2.3 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CAM38337.1 - 0.00033 20.7 0.0 0.001 19.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CAM38337.1 - 0.0024 18.3 6.9 0.051 14.0 0.6 3.7 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CAM38337.1 - 0.0038 17.0 0.0 0.022 14.5 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CAM38337.1 - 0.0058 16.9 2.8 0.055 13.7 0.1 3.0 2 1 1 3 3 3 1 AAA domain AAA_14 PF13173.6 CAM38337.1 - 0.017 15.1 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CAM38337.1 - 0.029 14.9 0.3 0.085 13.4 0.0 2.0 2 1 0 2 2 1 0 AAA domain Peptidase_M50B PF13398.6 CAM38337.1 - 0.03 14.0 0.0 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 Peptidase M50B-like DUF2075 PF09848.9 CAM38337.1 - 0.042 13.1 0.0 0.072 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.11 CAM38337.1 - 0.061 13.2 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 CAM38337.1 - 0.064 13.7 0.4 0.23 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 CAM38337.1 - 0.071 12.3 0.0 0.14 11.3 0.0 1.6 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 CAM38337.1 - 0.076 12.7 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein LPP PF04728.13 CAM38337.1 - 0.11 12.8 0.2 0.63 10.5 0.0 2.4 2 0 0 2 2 2 0 Lipoprotein leucine-zipper AAA_2 PF07724.14 CAM38337.1 - 0.13 12.4 0.2 1 9.5 0.2 2.4 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) SRP19 PF01922.17 CAM38338.1 - 1.8e-22 80.1 0.1 3.2e-22 79.3 0.0 1.4 1 1 0 1 1 1 1 SRP19 protein Pkinase PF00069.25 CAM38339.1 - 1.8e-21 76.7 0.0 2.1e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM38339.1 - 2.4e-07 30.3 0.0 6.4e-07 28.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAM38339.1 - 0.0023 16.8 0.0 0.0031 16.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase BTB_2 PF02214.22 CAM38340.1 - 1.2e-14 54.4 0.0 3e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Atg8 PF02991.16 CAM38341.1 - 1.6e-38 131.1 0.0 1.8e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 CAM38341.1 - 9.8e-08 32.3 0.0 1.2e-07 32.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 LRR_4 PF12799.7 CAM38342.2 - 3.3e-18 65.5 0.1 8.8e-05 22.8 0.0 5.0 4 1 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM38342.2 - 1.6e-05 24.6 2.5 0.55 10.0 0.5 4.6 3 1 3 6 6 6 2 Leucine rich repeat LRR_1 PF00560.33 CAM38342.2 - 0.36 11.6 11.0 45 5.2 0.4 6.5 7 1 0 7 7 7 0 Leucine Rich Repeat LRR_6 PF13516.6 CAM38342.2 - 0.7 10.1 7.2 4.5 7.6 0.2 5.0 6 0 0 6 6 6 0 Leucine Rich repeat Prominin PF05478.11 CAM38346.1 - 0.0064 14.5 3.0 0.0089 14.0 3.0 1.1 1 0 0 1 1 1 1 Prominin DUF1218 PF06749.12 CAM38346.1 - 0.43 11.1 15.1 0.2 12.2 6.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) Ldh_1_N PF00056.23 CAM38347.2 - 3.9e-43 146.9 0.0 5.1e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CAM38347.2 - 3.9e-41 140.8 0.0 5.5e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain NAD_binding_10 PF13460.6 CAM38347.2 - 0.0029 17.5 0.0 0.0087 16.0 0.1 1.7 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 CAM38347.2 - 0.015 14.3 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 CAM38347.2 - 0.029 14.8 0.1 0.064 13.7 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 CAM38347.2 - 0.047 13.0 0.1 0.51 9.6 0.1 2.1 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_hydro_3_C PF01915.22 CAM38347.2 - 0.1 12.5 0.1 0.52 10.2 0.1 1.8 1 1 2 3 3 3 0 Glycosyl hydrolase family 3 C-terminal domain Ldh_1_C PF02866.18 CAM38348.1 - 8.6e-37 126.6 0.0 1.3e-36 126.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 CAM38348.1 - 9.1e-37 126.3 0.0 1.3e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 CAM38348.1 - 0.00051 19.1 0.0 0.00077 18.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 CAM38348.1 - 0.0066 16.9 0.0 0.013 16.0 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 CAM38348.1 - 0.062 12.6 0.0 0.36 10.1 0.0 2.1 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DapB_N PF01113.20 CAM38348.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ldh_1_C PF02866.18 CAM38349.1 - 3.8e-46 157.1 0.0 6.4e-46 156.3 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 CAM38349.1 - 6e-46 156.0 0.2 8e-46 155.6 0.2 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain DapB_N PF01113.20 CAM38349.1 - 0.0015 18.6 0.0 0.0037 17.4 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 CAM38349.1 - 0.0017 18.8 0.1 0.0055 17.1 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 CAM38349.1 - 0.0022 17.1 0.0 0.003 16.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 CAM38349.1 - 0.0032 17.7 0.1 0.0067 16.7 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Ldh_1_C PF02866.18 CAM38350.2 - 1.6e-15 57.4 0.0 1.7e-14 54.1 0.0 2.1 1 1 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 CAM38350.2 - 2e-13 50.6 0.0 3.1e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain ADK PF00406.22 CAM38351.2 - 2.9e-24 85.9 0.0 3.8e-24 85.5 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CAM38351.2 - 6.3e-13 49.3 0.0 1.5e-12 48.1 0.0 1.5 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 CAM38351.2 - 3.8e-11 42.8 0.0 8e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid Hydin_ADK PF17213.3 CAM38351.2 - 2.6e-06 27.8 0.0 0.0046 17.3 0.0 2.3 2 0 0 2 2 2 2 Hydin Adenylate kinase-like domain AAA_18 PF13238.6 CAM38351.2 - 1.3e-05 25.7 0.0 2.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CAM38351.2 - 0.0082 16.4 0.0 0.016 15.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CAM38351.2 - 0.065 13.4 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 CAM38351.2 - 0.087 12.6 0.0 0.26 11.0 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Phage_holin_3_7 PF05449.11 CAM38351.2 - 0.17 11.9 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative 3TM holin, Phage_holin_3 AAA PF00004.29 CAM38351.2 - 0.18 12.2 0.3 0.72 10.3 0.1 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ADK PF00406.22 CAM38352.1 - 1.9e-51 174.2 0.0 2.2e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CAM38352.1 - 1.1e-23 84.2 0.0 1.5e-23 83.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 CAM38352.1 - 3e-15 55.9 0.1 6.1e-15 54.9 0.1 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 CAM38352.1 - 0.0004 20.9 0.1 0.0019 18.7 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CAM38352.1 - 0.0021 18.2 0.0 0.0057 16.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 CAM38352.1 - 0.011 16.0 0.0 0.068 13.4 0.0 2.0 1 1 1 2 2 2 0 Hydin Adenylate kinase-like domain AAA_28 PF13521.6 CAM38352.1 - 0.03 14.6 0.2 0.094 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain NUDIX PF00293.28 CAM38353.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 NUDIX domain Herpes_UL52 PF03121.15 CAM38353.1 - 3.2 7.8 5.8 6.5 6.8 5.8 1.4 1 0 0 1 1 1 0 Herpesviridae UL52/UL70 DNA primase TraH PF06122.11 CAM38354.1 - 0.092 12.0 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein HEPN_SAV2148 PF18725.1 CAM38354.1 - 0.17 11.3 4.1 2.2 7.6 0.5 2.4 2 0 0 2 2 2 0 SAV2148-like HEPN adh_short PF00106.25 CAM38355.1 - 1.1e-36 126.2 0.1 1.5e-36 125.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CAM38355.1 - 2.2e-22 79.8 0.0 2.9e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CAM38355.1 - 1.2e-05 25.3 0.0 1.9e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Exog_C PF18026.1 CAM38355.1 - 0.0047 16.9 0.3 0.015 15.3 0.1 1.9 2 0 0 2 2 2 1 Endo/exonuclease (EXOG) C-terminal domain Sacchrp_dh_NADP PF03435.18 CAM38355.1 - 0.03 14.6 0.0 0.054 13.8 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pkinase PF00069.25 CAM38357.1 - 1e-41 143.1 0.0 1.3e-41 142.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM38357.1 - 1.5e-22 80.2 0.0 1.7e-22 79.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM38357.1 - 1.5e-06 27.7 0.0 7.1e-06 25.5 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CAM38357.1 - 0.041 13.8 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family PIP49_C PF12260.8 CAM38357.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 DnaJ PF00226.31 CAM38358.1 - 7.4e-13 48.4 0.0 2.1e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain CLPTM1 PF05602.12 CAM38359.1 - 3e-102 342.9 0.1 3.7e-102 342.6 0.1 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 CAM38359.1 - 0.055 13.3 1.5 0.13 12.0 0.3 2.1 2 0 0 2 2 2 0 PQ loop repeat Reticulon PF02453.17 CAM38360.1 - 0.19 11.7 3.6 0.26 11.2 0.7 2.3 2 0 0 2 2 2 0 Reticulon peroxidase PF00141.23 CAM38361.1 - 4.2e-48 164.0 0.0 6.8e-48 163.3 0.0 1.3 1 1 0 1 1 1 1 Peroxidase G6PD_C PF02781.16 CAM38362.1 - 2.1e-107 358.6 0.0 2.7e-107 358.3 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 CAM38362.1 - 1.7e-55 188.4 0.0 3.2e-55 187.5 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain RIIa PF02197.17 CAM38362.1 - 0.0009 18.9 0.3 0.0037 16.9 0.1 2.0 2 0 0 2 2 2 1 Regulatory subunit of type II PKA R-subunit Methyltransf_25 PF13649.6 CAM38365.2 - 0.0065 17.2 0.0 0.027 15.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain NICE-1 PF15845.5 CAM38365.2 - 0.42 11.4 4.4 1.6 9.6 3.0 2.8 2 0 0 2 2 2 0 Cysteine-rich C-terminal 1 family DUF1935 PF09149.10 CAM38366.1 - 6.9e-125 408.6 6.6 9.4e-33 112.7 0.1 4.1 4 0 0 4 4 4 4 Domain of unknown function (DUF1935) Glyco_hydro_26 PF02156.15 CAM38366.1 - 0.0029 17.1 0.0 0.99 8.8 0.0 2.9 3 0 0 3 3 3 2 Glycosyl hydrolase family 26 OCRE PF17780.1 CAM38366.1 - 0.058 13.4 6.0 4.2 7.5 0.1 4.1 4 0 0 4 4 4 0 OCRE domain DUF1935 PF09149.10 CAM38367.1 - 3.8e-113 370.9 0.0 7.6e-29 100.1 0.0 4.1 4 0 0 4 4 4 4 Domain of unknown function (DUF1935) CS PF04969.16 CAM38368.1 - 6.6e-07 30.3 0.0 1e-06 29.7 0.0 1.3 1 0 0 1 1 1 1 CS domain EMP24_GP25L PF01105.24 CAM38369.2 - 1.2e-11 44.9 0.2 3.9e-11 43.2 0.2 1.8 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD CRF1 PF10380.9 CAM38369.2 - 0.039 14.3 0.1 0.13 12.6 0.1 1.8 1 1 0 1 1 1 0 Transcription factor CRF1 IFT81_CH PF18383.1 CAM38370.2 - 2.6e-31 108.4 0.3 1.5e-30 106.0 0.0 2.4 2 0 0 2 2 2 1 Intraflagellar transport 81 calponin homology domain Spc7 PF08317.11 CAM38370.2 - 0.00036 19.5 8.2 0.00036 19.5 8.2 4.1 1 1 1 4 4 4 2 Spc7 kinetochore protein Seryl_tRNA_N PF02403.22 CAM38370.2 - 0.0044 17.2 0.3 0.0044 17.2 0.3 6.2 2 1 4 7 7 7 1 Seryl-tRNA synthetase N-terminal domain Baculo_PEP_C PF04513.12 CAM38370.2 - 0.014 15.5 19.4 0.12 12.4 2.3 4.5 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cep57_MT_bd PF06657.13 CAM38370.2 - 0.048 14.1 0.1 0.048 14.1 0.1 5.3 6 2 2 8 8 8 0 Centrosome microtubule-binding domain of Cep57 DUF465 PF04325.13 CAM38370.2 - 0.08 13.0 1.9 0.23 11.5 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF465) IZUMO PF15005.6 CAM38370.2 - 0.16 12.5 15.8 0.84 10.1 0.2 4.4 3 2 0 4 4 4 0 Izumo sperm-egg fusion, Ig domain-associated Img2 PF05046.14 CAM38371.1 - 0.13 12.5 7.9 13 6.2 0.1 5.5 6 0 0 6 6 6 0 Mitochondrial large subunit ribosomal protein (Img2) Sas6_CC PF18594.1 CAM38371.1 - 4.8 7.1 7.0 40 4.1 0.4 4.5 4 0 0 4 4 4 0 Sas6/XLF/XRCC4 coiled-coil domain RIIa PF02197.17 CAM38373.1 - 2.3e-05 23.9 0.1 4.6e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Dpy-30 PF05186.13 CAM38373.1 - 6.9e-05 22.5 0.0 0.00012 21.7 0.0 1.5 1 1 0 1 1 1 1 Dpy-30 motif Pyr_redox_2 PF07992.14 CAM38374.2 - 1.2e-08 34.6 0.0 1.8e-06 27.4 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CAM38374.2 - 8.5e-05 22.7 0.1 0.00024 21.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CAM38374.2 - 0.00055 19.6 1.3 0.011 15.4 0.4 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 CAM38374.2 - 0.0053 16.0 0.0 0.0087 15.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 CAM38374.2 - 0.0078 15.1 0.2 0.013 14.4 0.2 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Lycopene_cycl PF05834.12 CAM38374.2 - 0.0089 15.1 0.3 0.0089 15.1 0.3 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein ThiF PF00899.21 CAM38374.2 - 0.035 13.4 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 ThiF family LapA_dom PF06305.11 CAM38374.2 - 0.036 13.9 2.2 0.26 11.1 0.7 2.7 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain NAD_binding_9 PF13454.6 CAM38374.2 - 0.056 13.4 2.2 0.16 11.9 0.1 2.7 3 0 0 3 3 2 0 FAD-NAD(P)-binding TrkA_N PF02254.18 CAM38374.2 - 0.075 13.3 0.1 0.16 12.2 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 CAM38374.2 - 0.14 12.4 0.1 0.36 11.1 0.1 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 CAM38374.2 - 0.15 11.3 0.9 0.31 10.2 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain GRAS PF03514.14 CAM38374.2 - 0.15 11.0 0.0 0.31 9.9 0.0 1.5 1 0 0 1 1 1 0 GRAS domain family Mqo PF06039.15 CAM38374.2 - 0.16 10.5 0.0 0.24 9.9 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) HI0933_like PF03486.14 CAM38374.2 - 0.18 10.5 0.7 1.2 7.8 0.3 2.2 2 0 0 2 2 2 0 HI0933-like protein Peptidase_C2 PF00648.21 CAM38375.2 - 1.4e-06 27.5 0.0 2.7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease DS PF01916.17 CAM38376.1 - 1.1e-54 185.6 0.0 6.3e-36 124.1 0.0 4.1 4 0 0 4 4 4 4 Deoxyhypusine synthase AAA PF00004.29 CAM38377.1 - 2.2e-09 37.8 0.1 5e-07 30.2 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CAM38377.1 - 3.3e-07 30.4 0.0 7e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CAM38377.1 - 0.00021 21.7 0.1 0.0011 19.3 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_6 PF12774.7 CAM38377.1 - 0.001 18.1 0.0 0.0016 17.5 0.0 1.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_33 PF13671.6 CAM38377.1 - 0.0014 18.8 0.0 0.0039 17.4 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 CAM38377.1 - 0.0024 18.1 0.4 0.011 16.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 CAM38377.1 - 0.0029 17.4 0.1 0.014 15.1 0.0 2.0 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 CAM38377.1 - 0.0034 17.8 0.0 0.0098 16.3 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 CAM38377.1 - 0.0044 17.6 0.0 0.011 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 CAM38377.1 - 0.0092 16.1 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 CAM38377.1 - 0.014 14.9 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 CAM38377.1 - 0.018 15.4 0.0 0.038 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CAM38377.1 - 0.02 14.6 0.5 0.17 11.6 0.0 2.4 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 CAM38377.1 - 0.034 14.1 0.0 0.067 13.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 CAM38377.1 - 0.035 13.2 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.12 CAM38377.1 - 0.053 13.4 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.6 CAM38377.1 - 0.066 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 CAM38377.1 - 0.07 12.9 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 CAM38377.1 - 0.077 12.9 0.1 0.48 10.3 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CAM38377.1 - 0.08 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain eIF-5_eIF-2B PF01873.17 CAM38378.1 - 5.7e-33 113.3 0.0 1.1e-32 112.4 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 CAM38378.1 - 0.002 18.2 0.3 0.0073 16.4 0.3 2.1 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon FYDLN_acid PF09538.10 CAM38378.1 - 1 10.0 6.6 0.73 10.5 1.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) RNA_pol_Rpb1_5 PF04998.17 CAM38379.2 - 3.4e-78 262.8 0.0 4.8e-78 262.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CAM38379.2 - 7.9e-67 224.6 0.0 1.4e-66 223.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 CAM38379.2 - 2.5e-54 184.7 0.0 3.7e-54 184.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 CAM38379.2 - 1.7e-31 109.3 0.0 3.5e-31 108.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CAM38379.2 - 3.1e-31 107.5 0.0 7.7e-31 106.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Rpr2 PF04032.16 CAM38379.2 - 2.9 8.2 7.4 0.61 10.4 1.7 2.5 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain COG6 PF06419.11 CAM38380.1 - 4.8e-48 163.8 1.3 2.4e-45 154.9 0.0 2.8 3 0 0 3 3 3 2 Conserved oligomeric complex COG6 Occludin_ELL PF07303.13 CAM38380.1 - 0.015 16.0 3.4 0.019 15.7 1.6 2.1 2 0 0 2 2 2 0 Occludin homology domain GCIP PF13324.6 CAM38380.1 - 0.027 14.1 0.1 0.095 12.3 0.1 2.0 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Syntaxin-6_N PF09177.11 CAM38380.1 - 2 9.0 4.1 1.7 9.3 0.2 3.0 3 1 0 3 3 3 0 Syntaxin 6, N-terminal PNP_UDP_1 PF01048.20 CAM38382.1 - 0.029 13.6 0.9 0.054 12.8 0.3 1.7 2 0 0 2 2 2 0 Phosphorylase superfamily DUF4785 PF16024.5 CAM38382.1 - 0.1 11.3 0.1 0.16 10.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4785) Ribosomal_S6 PF01250.17 CAM38383.1 - 0.005 17.1 0.1 0.0076 16.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S6 Fib_alpha PF08702.10 CAM38384.1 - 0.0018 18.5 2.0 0.17 12.1 0.0 2.9 2 1 0 2 2 2 1 Fibrinogen alpha/beta chain family GAS PF13851.6 CAM38384.1 - 0.0054 16.1 1.9 0.0054 16.1 1.9 2.4 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding EzrA PF06160.12 CAM38384.1 - 0.0055 14.9 5.2 0.11 10.7 0.1 2.3 2 0 0 2 2 2 2 Septation ring formation regulator, EzrA Spc7 PF08317.11 CAM38384.1 - 0.12 11.3 9.7 0.32 9.8 0.7 2.6 3 0 0 3 3 3 0 Spc7 kinetochore protein AIP3 PF03915.13 CAM38384.1 - 0.16 11.0 3.6 0.074 12.1 0.6 1.8 2 0 0 2 2 2 0 Actin interacting protein 3 Bap31_Bap29_C PF18035.1 CAM38384.1 - 0.5 10.4 2.9 0.48 10.5 0.9 2.1 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF4140 PF13600.6 CAM38384.1 - 1.2 9.6 12.9 1.2 9.6 0.8 3.1 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) COG2 PF06148.11 CAM38384.1 - 3.1 7.9 5.7 9.1 6.4 0.6 3.1 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 FUSC PF04632.12 CAM38386.1 - 0.2 10.2 2.8 1.2 7.6 0.1 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family Ribosomal_S25 PF03297.15 CAM38387.1 - 1.4e-36 124.7 5.5 1.7e-36 124.4 5.5 1.1 1 0 0 1 1 1 1 S25 ribosomal protein DUF3516 PF12029.8 CAM38387.1 - 0.13 11.3 1.4 0.13 11.3 1.4 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3516) WD40 PF00400.32 CAM38391.1 - 7.4e-40 134.2 20.9 7.8e-07 29.7 0.2 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM38391.1 - 2.1e-06 28.0 0.0 0.066 13.5 0.0 4.5 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ion_trans PF00520.31 CAM38392.2 - 4.6e-115 383.0 116.3 7.9e-36 123.5 25.9 4.2 4 0 0 4 4 4 4 Ion transport protein GPHH PF16905.5 CAM38392.2 - 0.0082 15.9 0.0 0.022 14.5 0.0 1.8 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated HEAT PF02985.22 CAM38393.1 - 3.4e-12 45.5 6.1 0.7 10.3 0.0 9.1 9 0 0 9 9 9 4 HEAT repeat HEAT_EZ PF13513.6 CAM38393.1 - 1.3e-11 44.7 5.6 9e-05 22.9 0.1 6.9 8 1 1 9 9 9 2 HEAT-like repeat Arm PF00514.23 CAM38393.1 - 3.4e-08 33.2 2.5 0.37 10.9 0.0 5.5 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat IBN_N PF03810.19 CAM38393.1 - 1.2e-07 31.6 0.0 9.6e-07 28.6 0.0 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 CAM38393.1 - 5.3e-07 30.0 11.4 0.0091 16.4 0.1 6.6 6 2 1 7 7 6 2 HEAT repeats Vac14_Fab1_bd PF12755.7 CAM38393.1 - 2.7e-05 24.7 3.8 0.46 11.1 0.1 5.5 4 3 2 6 6 6 2 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 CAM38393.1 - 8.6e-05 22.5 3.5 0.12 12.3 0.2 4.8 4 2 1 5 5 5 2 Domain of unknown function (DUF3385) CLASP_N PF12348.8 CAM38393.1 - 0.0018 17.9 0.6 0.19 11.3 0.1 3.3 3 0 0 3 3 3 1 CLASP N terminal V-ATPase_H_C PF11698.8 CAM38393.1 - 0.0021 18.2 0.6 1.8 8.7 0.0 4.1 4 0 0 4 4 4 1 V-ATPase subunit H ApoLp-III PF07464.11 CAM38393.1 - 0.018 15.1 0.7 0.19 11.8 0.0 2.8 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Telomere_reg-2 PF10193.9 CAM38393.1 - 0.28 11.6 6.6 2.9 8.4 0.1 4.5 3 2 1 4 4 4 0 Telomere length regulation protein Glycos_transf_2 PF00535.26 CAM38394.1 - 0.0025 17.7 0.0 0.004 17.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 GTP_EFTU PF00009.27 CAM38396.1 - 4.2e-43 147.2 0.2 6.5e-43 146.5 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 CAM38396.1 - 1.2e-30 105.8 1.3 2.1e-30 105.0 1.3 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 CAM38396.1 - 2.4e-14 53.1 0.2 7.9e-14 51.5 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus MMR_HSR1 PF01926.23 CAM38396.1 - 0.00014 22.0 0.0 0.00042 20.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 CAM38396.1 - 0.00051 19.7 0.1 0.0011 18.6 0.1 1.5 1 0 0 1 1 1 1 Ras family PduV-EutP PF10662.9 CAM38396.1 - 0.0036 17.1 0.0 0.03 14.1 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 CAM38396.1 - 0.014 14.7 0.1 0.3 10.3 0.0 2.4 2 0 0 2 2 2 0 Septin GTP_EFTU_D2 PF03144.25 CAM38396.1 - 0.02 15.3 0.0 0.048 14.0 0.0 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 2 DUF677 PF05055.12 CAM38397.1 - 0.00039 19.4 2.5 0.00045 19.2 2.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF677) MPS2 PF17060.5 CAM38397.1 - 0.0042 16.4 6.3 0.0047 16.2 6.3 1.0 1 0 0 1 1 1 1 Monopolar spindle protein 2 Val_tRNA-synt_C PF10458.9 CAM38397.1 - 0.014 15.7 7.1 0.41 11.0 3.0 3.5 3 1 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm Metal_resist PF13801.6 CAM38397.1 - 0.014 15.5 1.4 0.03 14.5 0.8 1.7 2 0 0 2 2 2 0 Heavy-metal resistance UPF0242 PF06785.11 CAM38397.1 - 0.035 14.2 5.5 0.039 14.1 5.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Ax_dynein_light PF10211.9 CAM38397.1 - 0.038 13.9 8.8 0.046 13.7 8.8 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain Caudo_TAP PF02413.17 CAM38397.1 - 0.05 13.8 2.9 0.066 13.4 2.9 1.1 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK DUF641 PF04859.12 CAM38397.1 - 0.064 13.6 5.8 0.079 13.3 5.8 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Phage_GP20 PF06810.11 CAM38397.1 - 0.067 13.0 10.7 0.024 14.5 7.9 1.7 1 1 0 1 1 1 0 Phage minor structural protein GP20 SlyX PF04102.12 CAM38397.1 - 0.083 13.5 5.5 0.37 11.4 2.6 2.3 1 1 1 2 2 2 0 SlyX Tho2 PF11262.8 CAM38397.1 - 0.095 11.9 5.8 0.12 11.5 5.8 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 NPV_P10 PF05531.12 CAM38397.1 - 0.11 13.0 1.2 0.21 12.1 1.2 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.9 CAM38397.1 - 0.12 11.5 5.8 0.12 11.4 5.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4446 PF14584.6 CAM38397.1 - 0.16 12.0 7.4 0.18 11.8 5.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) APC_N_CC PF16689.5 CAM38397.1 - 0.18 11.9 7.3 3.1 7.9 1.0 2.2 1 1 1 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain TSC22 PF01166.18 CAM38397.1 - 0.22 11.8 8.7 0.75 10.2 1.3 2.4 1 1 1 2 2 2 0 TSC-22/dip/bun family MCU PF04678.13 CAM38397.1 - 0.3 11.2 3.0 0.32 11.1 3.0 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Synaptobrevin PF00957.21 CAM38397.1 - 0.44 10.4 4.3 0.65 9.8 4.3 1.3 1 0 0 1 1 1 0 Synaptobrevin Spore_III_AB PF09548.10 CAM38397.1 - 0.57 10.3 4.6 0.63 10.1 4.6 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Csm1_N PF18504.1 CAM38397.1 - 0.79 10.1 11.1 2.1 8.8 4.5 2.4 1 1 1 2 2 2 0 Csm1 N-terminal domain TMPIT PF07851.13 CAM38397.1 - 1.3 8.2 4.2 1.4 8.1 4.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein ZapB PF06005.12 CAM38397.1 - 2 8.9 13.1 1.6 9.2 11.8 1.6 1 1 0 1 1 1 0 Cell division protein ZapB RRF PF01765.19 CAM38397.1 - 4.8 7.1 14.4 6 6.8 7.8 2.1 1 1 0 2 2 2 0 Ribosome recycling factor HTH_28 PF13518.6 CAM38398.1 - 1.8 8.7 5.0 10 6.3 0.1 3.8 3 0 0 3 3 3 0 Helix-turn-helix domain NMO PF03060.15 CAM38400.1 - 8.4e-61 206.2 0.7 1.1e-40 140.1 0.9 2.0 1 1 1 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 CAM38400.1 - 9.9e-10 38.0 0.8 1.5e-09 37.3 0.8 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 CAM38400.1 - 5e-09 35.6 0.3 2.5e-07 30.0 0.3 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.21 CAM38400.1 - 3.6e-07 29.7 0.1 7.7e-07 28.6 0.2 1.5 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase ThiG PF05690.14 CAM38400.1 - 7.1e-05 22.2 0.6 0.00012 21.4 0.6 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 CAM38400.1 - 0.0018 17.5 2.4 0.0036 16.5 2.4 1.5 1 1 0 1 1 1 1 Conserved region in glutamate synthase Dus PF01207.17 CAM38400.1 - 0.0057 15.8 0.1 0.013 14.6 0.0 1.6 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 CAM38400.1 - 0.023 14.2 0.1 0.04 13.4 0.1 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein NanE PF04131.14 CAM38400.1 - 0.034 13.3 0.1 0.064 12.4 0.1 1.4 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Sec20 PF03908.13 CAM38401.2 - 0.022 14.7 1.4 0.065 13.2 1.4 1.8 1 0 0 1 1 1 0 Sec20 Pantoate_transf PF02548.15 CAM38402.1 - 0.19 11.1 2.7 0.28 10.5 0.7 2.0 2 0 0 2 2 2 0 Ketopantoate hydroxymethyltransferase PMEI PF04043.15 CAM38402.1 - 0.85 9.9 9.4 0.16 12.3 3.6 2.6 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor LRR_8 PF13855.6 CAM38403.2 - 0.0051 16.5 0.2 0.11 12.2 0.0 2.9 2 0 0 2 2 2 1 Leucine rich repeat JAB PF01398.21 CAM38404.1 - 6.8e-28 97.0 0.0 1.4e-27 96.0 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 CAM38404.1 - 1.6e-08 34.3 0.0 2.7e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain MitMem_reg PF13012.6 CAM38404.1 - 0.00064 20.1 0.2 0.0015 19.0 0.2 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function ABC_tran PF00005.27 CAM38406.2 - 1.1e-38 132.9 0.0 4e-22 79.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CAM38406.2 - 2.6e-35 122.4 21.4 1.8e-20 73.7 6.9 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 CAM38406.2 - 7.9e-08 32.0 0.7 0.0037 16.7 0.0 4.1 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CAM38406.2 - 4.4e-06 26.7 0.1 2.2 8.0 0.0 4.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CAM38406.2 - 8.9e-06 25.7 0.0 0.038 13.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CAM38406.2 - 1.3e-05 25.2 0.1 0.017 15.2 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 CAM38406.2 - 0.0003 20.5 0.0 0.41 10.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 CAM38406.2 - 0.00061 20.2 4.5 0.015 15.7 0.0 3.9 2 1 0 2 2 2 1 AAA ATPase domain ESM4 PF15952.5 CAM38406.2 - 0.0011 19.4 0.6 0.0033 17.9 0.0 2.0 2 0 0 2 2 2 1 Enhancer of split M4 family AAA_25 PF13481.6 CAM38406.2 - 0.0021 17.7 0.4 0.13 11.8 0.0 3.2 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.6 CAM38406.2 - 0.01 16.1 0.0 0.39 11.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 CAM38406.2 - 0.011 16.3 0.1 3.1 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CAM38406.2 - 0.015 15.7 0.0 2.9 8.3 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AIG1 PF04548.16 CAM38406.2 - 0.017 14.5 0.1 1.3 8.3 0.2 2.4 2 0 0 2 2 2 0 AIG1 family Dynamin_N PF00350.23 CAM38406.2 - 0.023 14.8 0.1 1 9.4 0.2 2.5 2 0 0 2 2 2 0 Dynamin family RNA_helicase PF00910.22 CAM38406.2 - 0.067 13.6 0.1 4.6 7.7 0.0 3.1 3 0 0 3 3 3 0 RNA helicase ATPase_2 PF01637.18 CAM38406.2 - 0.25 11.2 0.0 0.86 9.5 0.0 1.9 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea CENP-F_leu_zip PF10473.9 CAM38407.1 - 0.84 9.7 35.1 0.31 11.1 1.8 4.9 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COMM_domain PF07258.14 CAM38407.1 - 0.92 9.7 4.8 21 5.3 1.9 3.5 2 1 0 2 2 2 0 COMM domain DUF948 PF06103.11 CAM38407.1 - 4.7 7.5 12.4 2.1 8.6 0.5 4.3 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF2039 PF10217.9 CAM38409.1 - 6.5e-23 80.9 21.9 1e-22 80.3 21.9 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) Tankyrase_bdg_C PF15327.6 CAM38409.1 - 0.02 15.3 0.5 0.028 14.9 0.5 1.2 1 0 0 1 1 1 0 Tankyrase binding protein C terminal domain SPESP1 PF15754.5 CAM38409.1 - 0.097 11.8 0.2 0.12 11.5 0.2 1.1 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 Cript PF10235.9 CAM38409.1 - 1.1 9.9 17.0 3.9 8.1 17.0 2.0 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT Neuropeptide_S PF14993.6 CAM38410.1 - 0.0046 16.8 1.2 1.9 8.4 0.4 3.2 2 0 0 2 2 2 2 Neuropeptide S precursor protein Tcp10_C PF07202.13 CAM38411.1 - 0.0053 16.7 0.4 0.019 14.9 0.4 1.9 1 1 0 1 1 1 1 T-complex protein 10 C-terminus Sod_Fe_C PF02777.18 CAM38411.1 - 0.011 15.9 0.0 0.029 14.5 0.0 1.7 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, C-terminal domain SpoIIE PF07228.12 CAM38412.1 - 7.3e-09 35.8 0.0 9.2e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 CAM38412.1 - 0.013 15.1 0.0 0.024 14.3 0.0 1.4 1 1 0 1 1 1 0 Protein phosphatase 2C MMS1_N PF10433.9 CAM38412.1 - 0.019 13.6 0.0 0.021 13.5 0.0 1.0 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term PP2C PF00481.21 CAM38412.1 - 0.07 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein phosphatase 2C CBF PF03914.17 CAM38413.2 - 1.8e-27 96.4 0.6 3e-27 95.7 0.6 1.3 1 0 0 1 1 1 1 CBF/Mak21 family DUF4844 PF16133.5 CAM38414.1 - 0.00078 20.0 0.1 1.6 9.3 0.0 2.9 2 1 1 3 3 3 2 Domain of unknown function (DUF4844) NAD_binding_10 PF13460.6 CAM38415.1 - 2.4e-08 34.1 0.0 2.7e-05 24.1 0.1 2.3 2 0 0 2 2 2 2 NAD(P)H-binding NmrA PF05368.13 CAM38415.1 - 2.6e-05 23.9 0.3 7.3e-05 22.4 0.1 1.7 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 CAM38415.1 - 0.015 14.8 0.0 0.094 12.2 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 CAM38415.1 - 0.054 12.7 0.1 0.087 12.0 0.1 1.2 1 0 0 1 1 1 0 Male sterility protein 3HCDH_N PF02737.18 CAM38415.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.25 CAM38415.1 - 0.14 11.6 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Shikimate_DH PF01488.20 CAM38415.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Metallophos PF00149.28 CAM38417.1 - 7.6e-32 111.5 0.1 1e-31 111.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CAM38417.1 - 1.8e-14 53.9 0.8 2.9e-14 53.2 0.8 1.3 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos PF00149.28 CAM38418.1 - 4.8e-31 108.9 0.1 6.8e-31 108.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CAM38418.1 - 2.8e-14 53.3 0.7 4.7e-14 52.5 0.7 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos PF00149.28 CAM38419.1 - 1.7e-31 110.3 0.1 2.3e-31 109.9 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CAM38419.1 - 1.6e-14 54.1 1.9 2.5e-14 53.4 1.9 1.3 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Pcc1 PF09341.10 CAM38420.1 - 2e-09 37.4 0.2 3.6e-09 36.6 0.2 1.4 1 1 0 1 1 1 1 Transcription factor Pcc1 EF1_GNE PF00736.19 CAM38421.1 - 3.5e-27 94.4 0.8 5.2e-27 93.9 0.8 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain GST_C_2 PF13410.6 CAM38422.1 - 0.053 13.5 0.0 0.09 12.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain EF1_GNE PF00736.19 CAM38423.1 - 1.9e-26 92.1 0.8 2.9e-26 91.5 0.8 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain GST_C_2 PF13410.6 CAM38423.1 - 0.011 15.7 0.0 0.028 14.4 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Amastin PF07344.11 CAM38424.1 - 1.1e-53 181.3 6.5 2.5e-53 180.1 6.8 1.4 2 0 0 2 2 2 1 Amastin surface glycoprotein GFO_IDH_MocA_C PF02894.17 CAM38424.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain TcpE PF12648.7 CAM38424.1 - 4.1 8.0 7.5 0.5 10.9 1.4 2.2 2 1 0 2 2 2 0 TcpE family Amastin PF07344.11 CAM38425.1 - 3.2e-46 157.0 14.4 3.8e-46 156.7 14.4 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF5090 PF17009.5 CAM38425.1 - 0.54 10.2 2.7 1.1 9.2 2.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5090) DUF4293 PF14126.6 CAM38425.1 - 1 9.6 7.4 2.3 8.5 7.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) Amastin PF07344.11 CAM38426.1 - 1.7e-49 167.6 14.7 2.3e-49 167.2 14.7 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF4293 PF14126.6 CAM38426.1 - 0.061 13.6 10.2 0.12 12.6 10.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) Tmemb_170 PF10190.9 CAM38426.1 - 0.28 11.6 13.7 0.12 12.7 7.7 2.2 2 0 0 2 2 2 0 Putative transmembrane protein 170 Conotoxin PF02950.17 CAM38426.1 - 0.5 11.4 0.0 0.5 11.4 0.0 2.3 3 0 0 3 3 3 0 Conotoxin EF1_GNE PF00736.19 CAM38427.1 - 1.1e-26 92.8 0.8 1.8e-26 92.2 0.8 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain GST_C_2 PF13410.6 CAM38427.1 - 0.0097 15.9 0.0 0.021 14.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Metallophos PF00149.28 CAM38428.1 - 2.3e-32 113.2 0.0 2.8e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CAM38428.1 - 1.7e-05 25.2 0.0 3.1e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Ribosomal_L13 PF00572.18 CAM38429.1 - 2.2e-06 27.9 3.8 2.8e-05 24.4 0.9 2.6 2 1 0 2 2 2 1 Ribosomal protein L13 DUF4455 PF14643.6 CAM38429.1 - 0.011 14.4 1.3 0.016 13.9 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) Pox_Ag35 PF03286.14 CAM38430.1 - 0.27 11.0 6.1 0.52 10.1 6.1 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Prothymosin PF03247.14 CAM38430.1 - 0.93 10.0 22.9 2.4 8.6 22.9 1.6 1 0 0 1 1 1 0 Prothymosin/parathymosin family RNA_pol_Rpb6 PF01192.22 CAM38432.1 - 1.8e-14 53.3 1.8 2.2e-14 53.1 0.3 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb6 DUF2169 PF09937.9 CAM38432.1 - 0.029 13.8 0.0 0.033 13.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2169) UQ_con PF00179.26 CAM38433.1 - 5.1e-17 61.8 0.0 7.8e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Med3 PF11593.8 CAM38433.1 - 0.0019 17.5 7.8 0.0023 17.2 7.8 1.1 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal PAP1 PF08601.10 CAM38433.1 - 0.44 10.2 6.1 0.57 9.8 6.1 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 UQ_con PF00179.26 CAM38435.1 - 1.8e-17 63.3 0.0 2.7e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Med3 PF11593.8 CAM38435.1 - 0.00064 19.0 7.2 0.00076 18.8 7.2 1.1 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal UQ_con PF00179.26 CAM38436.1 - 5.2e-17 61.8 0.0 7.8e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Med3 PF11593.8 CAM38436.1 - 0.0049 16.1 7.3 0.0066 15.7 7.3 1.1 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal Macoilin PF09726.9 CAM38438.1 - 0.73 8.3 3.1 0.94 8.0 3.1 1.1 1 0 0 1 1 1 0 Macoilin family PAP2 PF01569.21 CAM38438.1 - 1.1 9.0 5.9 1.3 8.8 1.5 2.5 2 0 0 2 2 2 0 PAP2 superfamily SR-25 PF10500.9 CAM38438.1 - 2.1 7.9 14.1 5 6.7 14.1 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-Tim10_DDP PF02953.15 CAM38439.1 - 0.043 13.5 0.5 0.21 11.2 0.0 2.1 2 0 0 2 2 2 0 Tim10/DDP family zinc finger Pkinase PF00069.25 CAM38440.1 - 6e-41 140.6 0.0 2.4e-30 105.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM38440.1 - 6.7e-19 68.2 0.0 8.8e-14 51.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CAM38440.1 - 0.07 13.0 0.3 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 CAM38440.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Amastin PF07344.11 CAM38441.1 - 4.6e-32 111.0 10.9 5.3e-32 110.8 10.9 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein LHC PF00556.20 CAM38441.1 - 0.0059 16.8 1.2 0.025 14.8 0.2 2.4 2 1 0 2 2 2 1 Antenna complex alpha/beta subunit Amastin PF07344.11 CAM38442.1 - 1.3e-42 145.3 12.1 1.6e-42 145.0 12.1 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Myosin_head PF00063.21 CAM38443.1 - 5.1e-210 699.2 0.0 2.1e-126 422.8 0.0 2.1 2 0 0 2 2 2 2 Myosin head (motor domain) Myosin_TH1 PF06017.13 CAM38443.1 - 3.6e-07 30.0 0.0 0.008 15.9 0.1 2.6 3 0 0 3 3 3 2 Unconventional myosin tail, actin- and lipid-binding FYVE PF01363.21 CAM38443.1 - 7.1e-05 22.9 8.9 0.00018 21.6 8.9 1.6 1 0 0 1 1 1 1 FYVE zinc finger AAA_16 PF13191.6 CAM38443.1 - 0.027 14.9 2.3 0.043 14.2 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_11 PF13086.6 CAM38443.1 - 0.054 13.3 5.0 1.3 8.7 4.2 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CAM38443.1 - 0.15 12.3 0.0 0.42 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain HTH_30 PF13556.6 CAM38444.1 - 0.035 13.9 0.3 0.14 12.0 0.3 2.0 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain FAD_SOX PF18371.1 CAM38444.1 - 0.14 12.6 0.1 0.32 11.4 0.1 1.6 1 0 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase N2227 PF07942.12 CAM38445.1 - 1.1e-94 316.7 0.0 1.4e-94 316.3 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 CAM38445.1 - 0.16 11.8 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain EF-hand_7 PF13499.6 CAM38446.1 - 6.1e-09 36.2 0.1 9.6e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CAM38446.1 - 6.9e-09 35.4 0.2 1.4e-08 34.5 0.2 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CAM38446.1 - 1.5e-06 27.3 0.1 0.0012 18.2 0.2 2.8 2 1 1 3 3 3 2 EF hand EF-hand_5 PF13202.6 CAM38446.1 - 0.00015 21.1 0.3 0.005 16.3 0.1 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CAM38446.1 - 0.00023 20.9 0.1 0.07 13.1 0.1 2.7 1 1 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 CAM38446.1 - 0.069 13.1 0.0 0.36 10.8 0.0 1.9 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand UPRTase PF14681.6 CAM38447.2 - 3.4e-71 239.0 0.0 4e-71 238.7 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 CAM38447.2 - 4.7e-06 26.2 0.0 8.2e-06 25.4 0.0 1.3 1 1 0 1 1 1 1 Phosphoribosyl transferase domain SET PF00856.28 CAM38448.1 - 4e-13 50.1 0.0 1.9e-12 47.9 0.0 2.1 2 1 0 2 2 2 1 SET domain TPR_2 PF07719.17 CAM38448.1 - 1.7e-09 37.0 6.6 0.00059 19.7 0.2 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CAM38448.1 - 0.00032 20.9 6.3 0.12 12.6 0.3 4.1 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CAM38448.1 - 0.00036 20.5 1.0 0.16 12.2 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CAM38448.1 - 0.0005 19.8 11.4 0.01 15.6 0.5 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 CAM38448.1 - 0.0012 19.5 5.6 0.084 13.7 0.0 4.8 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 CAM38448.1 - 0.063 13.3 2.0 17 5.7 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 CAM38448.1 - 0.19 11.7 4.0 0.72 9.8 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CAM38448.1 - 2 9.2 3.8 50 4.8 0.2 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_M41 PF01434.18 CAM38449.2 - 7.1e-40 136.9 0.0 1.2e-39 136.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CAM38449.2 - 4.9e-39 133.8 0.0 8.6e-39 133.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAM38449.2 - 1.9e-10 40.4 0.0 4.8e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 CAM38449.2 - 0.00034 20.8 0.0 0.00073 19.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CAM38449.2 - 0.00038 20.2 0.0 0.0012 18.6 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CAM38449.2 - 0.00044 20.7 0.0 0.15 12.5 0.1 2.7 1 1 1 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 CAM38449.2 - 0.0032 16.7 0.0 0.0052 16.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 CAM38449.2 - 0.0032 17.5 1.8 0.2 11.7 0.2 3.9 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CAM38449.2 - 0.01 16.1 0.0 0.31 11.3 0.0 2.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CAM38449.2 - 0.014 15.0 0.1 4.5 6.8 0.0 2.6 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.6 CAM38449.2 - 0.032 14.2 0.0 0.064 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CAM38449.2 - 0.054 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 CAM38449.2 - 0.066 12.6 0.1 0.19 11.1 0.1 1.7 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 CAM38449.2 - 0.085 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 CAM38449.2 - 0.18 12.3 0.0 1 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Lipase_3 PF01764.25 CAM38450.1 - 3.6e-08 33.4 0.1 7.8e-08 32.3 0.1 1.6 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 CAM38450.1 - 3.1e-05 23.3 0.7 6.9e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CAM38450.1 - 0.00051 20.7 0.1 0.00051 20.7 0.1 3.6 4 2 0 4 4 4 1 Alpha/beta hydrolase family DUF2974 PF11187.8 CAM38450.1 - 0.0022 17.6 0.2 0.0091 15.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.7 CAM38450.1 - 0.013 15.3 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CAM38450.1 - 0.017 14.8 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 CAM38450.1 - 0.025 14.7 0.1 0.06 13.4 0.1 1.6 1 0 0 1 1 1 0 Thioesterase domain CytochromB561_N PF09786.9 CAM38450.1 - 0.026 13.5 0.0 0.044 12.8 0.0 1.3 1 0 0 1 1 1 0 Cytochrome B561, N terminal PGAP1 PF07819.13 CAM38450.1 - 0.066 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein LAP1C PF05609.12 CAM38450.1 - 0.21 10.7 0.1 0.36 9.9 0.1 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Amastin PF07344.11 CAM38452.1 - 2.7e-54 183.2 7.0 3.4e-54 182.9 7.0 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF423 PF04241.15 CAM38452.1 - 0.04 14.1 3.4 3.7 7.8 2.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF423) Amastin PF07344.11 CAM38453.1 - 2.7e-54 183.2 7.0 3.4e-54 182.9 7.0 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF423 PF04241.15 CAM38453.1 - 0.04 14.1 3.4 3.7 7.8 2.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF423) Amastin PF07344.11 CAM38454.1 - 1.2e-53 181.1 9.0 1.5e-53 180.8 9.0 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF423 PF04241.15 CAM38454.1 - 0.0046 17.1 5.4 0.34 11.1 3.9 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF423) DEAD PF00270.29 CAM38456.1 - 3.7e-05 23.6 0.0 7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAM38456.1 - 0.00014 22.1 0.0 0.00078 19.8 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_7 PF12775.7 CAM38456.1 - 0.002 17.7 0.0 0.0042 16.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_30 PF13604.6 CAM38456.1 - 0.027 14.2 0.1 0.065 13.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain DUF4648 PF15505.6 CAM38456.1 - 0.12 13.3 0.0 0.35 11.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4648) T2SSE PF00437.20 CAM38456.1 - 0.13 11.3 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein UQ_con PF00179.26 CAM38457.1 - 1.5e-22 79.8 0.0 1.7e-22 79.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Acyltransferase PF01553.21 CAM38458.1 - 1.7e-17 63.3 0.0 3.6e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase SPX PF03105.19 CAM38459.1 - 2.9 7.7 6.4 4 7.3 6.4 1.2 1 0 0 1 1 1 0 SPX domain SBDS_C PF09377.10 CAM38460.1 - 1e-25 90.0 0.1 2.4e-25 88.8 0.1 1.6 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 CAM38460.1 - 1.9e-23 82.3 0.3 1.9e-23 82.3 0.3 1.9 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein CH_2 PF06294.11 CAM38461.1 - 1e-30 105.7 0.0 1.7e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 CAM38461.1 - 2.5e-19 68.9 0.0 4.4e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain TMF_DNA_bd PF12329.8 CAM38461.1 - 0.049 13.6 0.7 0.32 11.0 0.6 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Csm1_N PF18504.1 CAM38461.1 - 0.56 10.6 4.6 0.39 11.1 2.0 2.1 2 0 0 2 2 2 0 Csm1 N-terminal domain Dus PF01207.17 CAM38463.1 - 9.3e-53 179.3 0.0 7.4e-51 173.1 0.0 2.2 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 CAM38463.1 - 1.5e-05 24.6 0.0 2.9e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 CAM38463.1 - 0.0026 17.1 0.0 0.005 16.2 0.0 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG BMC PF00936.19 CAM38463.1 - 0.026 14.5 0.8 0.051 13.6 0.0 1.9 2 0 0 2 2 2 0 BMC domain BKACE PF05853.12 CAM38463.1 - 0.093 12.0 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme NMO PF03060.15 CAM38463.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase Cnn_1N PF07989.11 CAM38467.1 - 0.00075 19.6 1.8 0.00075 19.6 1.8 7.3 3 2 4 7 7 7 2 Centrosomin N-terminal motif 1 KxDL PF10241.9 CAM38467.1 - 0.0025 18.1 10.2 0.0025 18.1 10.2 4.9 3 3 2 5 5 5 1 Uncharacterized conserved protein Rootletin PF15035.6 CAM38467.1 - 0.013 15.6 6.6 0.013 15.6 6.6 4.3 1 1 3 4 4 4 0 Ciliary rootlet component, centrosome cohesion HALZ PF02183.18 CAM38467.1 - 0.15 12.3 0.3 0.15 12.3 0.3 6.7 7 1 0 7 7 7 0 Homeobox associated leucine zipper Baculo_PEP_C PF04513.12 CAM38467.1 - 9.1 6.3 32.1 2.8 8.0 10.1 4.3 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus HA2 PF04408.23 CAM38470.1 - 1.4e-12 47.9 0.0 5.3e-12 46.0 0.0 2.1 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CAM38470.1 - 5e-11 42.9 0.0 1.8e-10 41.1 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CAM38470.1 - 7.9e-08 32.3 0.1 2.3e-07 30.7 0.1 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.26 CAM38470.1 - 0.0032 18.1 0.3 0.022 15.4 0.1 2.4 2 0 0 2 2 2 1 Double-stranded RNA binding motif AAA_22 PF13401.6 CAM38470.1 - 0.0062 16.8 0.1 0.019 15.2 0.1 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CAM38470.1 - 0.0098 15.0 0.0 0.021 13.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Rad17 PF03215.15 CAM38470.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain ATPase PF06745.13 CAM38470.1 - 0.23 10.8 0.0 0.46 9.8 0.0 1.4 1 0 0 1 1 1 0 KaiC YabA PF06156.13 CAM38472.2 - 0.061 14.0 3.0 0.13 12.9 1.1 2.5 2 0 0 2 2 2 0 Initiation control protein YabA DUF1640 PF07798.11 CAM38472.2 - 0.14 12.2 2.0 0.35 10.9 2.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF2052 PF09747.9 CAM38472.2 - 7.4 6.6 7.6 7.1 6.7 0.1 3.3 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) Shugoshin_N PF07558.11 CAM38472.2 - 7.8 6.5 5.9 3.1 7.7 1.6 2.5 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DNA_pol_A_exo1 PF01612.20 CAM38473.1 - 2.2e-12 47.0 0.0 6.1e-12 45.6 0.0 1.7 2 0 0 2 2 2 1 3'-5' exonuclease zf-CCCH PF00642.24 CAM38473.1 - 0.0077 16.1 0.7 0.0077 16.1 0.7 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LZ3wCH PF18517.1 CAM38473.1 - 0.013 15.6 0.4 0.051 13.7 0.4 1.9 1 0 0 1 1 1 0 Leucine zipper with capping helix domain NIF PF03031.18 CAM38474.1 - 2.9e-30 105.1 0.0 2e-28 99.1 0.0 2.9 2 1 0 2 2 2 1 NLI interacting factor-like phosphatase Ntox34 PF15606.6 CAM38474.1 - 0.051 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial toxin 34 BtrH_N PF14399.6 CAM38474.1 - 0.069 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal DUF2608 PF11019.8 CAM38474.1 - 0.093 12.2 0.1 7.6 5.9 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2608) DNA_pol_A PF00476.20 CAM38475.1 - 1.2e-95 320.8 0.0 5.1e-84 282.5 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase family A Piezo_RRas_bdg PF12166.8 CAM38476.1 - 2.8e-90 303.7 0.0 3.7e-90 303.2 0.0 1.2 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain UPF0220 PF05255.11 CAM38476.1 - 0.2 11.2 4.8 1.6 8.2 2.4 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0220) SIR2_2 PF13289.6 CAM38478.1 - 0.032 14.4 0.0 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 SIR2-like domain OsmC PF02566.19 CAM38479.1 - 2.7e-06 27.8 0.5 5.8e-06 26.7 0.5 1.5 1 0 0 1 1 1 1 OsmC-like protein MAGE_N PF12440.8 CAM38479.1 - 6.2 7.6 21.2 9.3 7.0 1.5 3.4 3 0 0 3 3 3 0 Melanoma associated antigen family N terminal BCS1_N PF08740.11 CAM38482.1 - 6e-31 107.9 3.4 1.1e-30 107.1 3.4 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 CAM38482.1 - 7.3e-20 71.7 0.0 1.9e-19 70.4 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CAM38482.1 - 0.00078 19.9 0.4 0.013 15.9 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 CAM38482.1 - 0.00097 19.1 0.5 0.013 15.5 0.2 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CAM38482.1 - 0.0013 18.5 0.0 0.0029 17.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 CAM38482.1 - 0.002 17.3 0.1 0.0045 16.2 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Rad17 PF03215.15 CAM38482.1 - 0.0026 17.7 0.0 0.01 15.8 0.0 2.1 2 1 1 3 3 3 1 Rad17 P-loop domain AAA_11 PF13086.6 CAM38482.1 - 0.0036 17.1 0.0 0.0072 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CAM38482.1 - 0.0039 17.7 0.0 0.009 16.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_18 PF13238.6 CAM38482.1 - 0.006 17.1 0.0 0.014 15.9 0.0 1.6 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 CAM38482.1 - 0.0076 16.6 0.0 0.022 15.1 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 CAM38482.1 - 0.018 15.2 0.0 0.038 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CAM38482.1 - 0.03 14.6 0.0 0.21 11.8 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CAM38482.1 - 0.062 12.9 0.4 0.26 10.9 0.2 2.2 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 CAM38482.1 - 0.063 13.2 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 NACHT domain TIP49 PF06068.13 CAM38482.1 - 0.16 11.2 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase_2 PF01637.18 CAM38482.1 - 0.16 11.9 0.0 7.9 6.3 0.0 2.3 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Syntaxin PF00804.25 CAM38484.1 - 0.12 12.0 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Syntaxin KAR9 PF08580.10 CAM38484.1 - 2 6.8 14.3 3.5 6.1 14.3 1.3 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF2220 PF09983.9 CAM38486.2 - 0.0094 15.3 0.8 0.0094 15.3 0.8 1.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria C-term(DUF2220) Mobilization_B PF17511.2 CAM38487.2 - 0.047 14.0 2.0 0.17 12.3 2.0 1.9 1 0 0 1 1 1 0 Mobilization protein B VPS13 PF16908.5 CAM38488.2 - 2.4e-34 119.2 0.0 1.9e-33 116.3 0.0 2.4 1 1 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 CAM38488.2 - 1.1e-27 96.5 0.0 2.4e-27 95.3 0.0 1.6 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 SHR-BD PF06650.12 CAM38488.2 - 2.4e-15 56.6 0.0 2.4e-10 40.3 0.0 3.4 2 1 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 BDV_P24 PF06595.11 CAM38488.2 - 0.094 12.6 0.1 0.25 11.2 0.1 1.7 1 0 0 1 1 1 0 Borna disease virus P24 protein 2-Hacid_dh_C PF02826.19 CAM38489.1 - 4.3e-42 143.5 0.0 5.8e-42 143.1 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 CAM38489.1 - 1.4e-06 28.5 0.3 2.8e-06 27.5 0.3 1.4 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 CAM38489.1 - 6.2e-05 23.2 0.1 8e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 CAM38489.1 - 0.00017 21.2 0.0 0.00022 20.8 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 CAM38489.1 - 0.00024 20.5 0.0 0.00039 19.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.17 CAM38489.1 - 0.0025 18.3 0.2 0.0056 17.2 0.1 1.7 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ELFV_dehydrog PF00208.21 CAM38489.1 - 0.028 14.2 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Pyr_redox PF00070.27 CAM38489.1 - 0.038 14.6 0.2 0.071 13.7 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Kinesin PF00225.23 CAM38490.1 - 3e-76 256.5 0.0 4e-76 256.1 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CAM38490.1 - 6.6e-23 81.3 0.0 5.3e-20 71.9 0.0 2.3 2 0 0 2 2 2 2 Microtubule binding DEAD PF00270.29 CAM38491.1 - 4.4e-05 23.3 0.0 8.1e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_7 PF12775.7 CAM38491.1 - 0.00067 19.2 0.0 0.0027 17.3 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 CAM38491.1 - 0.05 13.3 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 CAM38491.1 - 0.14 11.2 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein UQ_con PF00179.26 CAM38492.1 - 1.5e-22 79.8 0.0 1.7e-22 79.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Amastin PF07344.11 CAM38494.1 - 4.9e-52 175.9 10.4 6e-52 175.6 10.4 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF1467 PF07330.12 CAM38494.1 - 9.1 6.3 13.0 2.9 7.9 0.1 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1467) Zeta_toxin PF06414.12 CAM38495.1 - 1e-10 41.3 0.0 2.7e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 CAM38495.1 - 0.0084 16.3 0.0 0.022 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain Peptidase_C15 PF01470.17 CAM38496.1 - 1.4e-10 41.7 0.6 0.00024 21.3 0.1 2.2 2 0 0 2 2 2 2 Pyroglutamyl peptidase RCC1 PF00415.18 CAM38498.1 - 1.2e-21 77.1 1.8 1.7e-07 31.7 0.1 4.6 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CAM38498.1 - 4e-16 58.4 12.5 3.6e-10 39.4 1.7 5.5 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Paralemmin PF03285.15 CAM38498.1 - 0.0036 16.9 2.9 0.0089 15.6 2.9 1.7 1 0 0 1 1 1 1 Paralemmin TPR_12 PF13424.6 CAM38499.1 - 3.1e-05 24.2 1.2 0.019 15.2 0.4 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat IQ PF00612.27 CAM38499.1 - 0.0014 18.2 0.3 0.0014 18.2 0.3 7.9 7 1 1 8 8 8 3 IQ calmodulin-binding motif TMEM239 PF15841.5 CAM38499.1 - 0.35 10.8 3.0 1.4 8.8 0.6 2.5 2 0 0 2 2 2 0 Transmembrane protein 239 family DEAD PF00270.29 CAM38500.1 - 3.2e-45 154.1 0.1 1.3e-44 152.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAM38500.1 - 2.8e-24 85.6 0.0 8.5e-24 84.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 CAM38500.1 - 5e-11 42.7 2.8 1.4e-10 41.3 2.8 1.8 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.15 CAM38500.1 - 3.7e-05 23.8 0.0 0.00016 21.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CAM38500.1 - 0.11 12.8 1.2 1 9.6 0.2 2.9 2 1 0 2 2 2 0 AAA domain FtsX PF02687.21 CAM38502.1 - 4.5e-14 52.7 20.1 4.1e-10 40.0 6.1 6.7 6 1 0 6 6 6 2 FtsX-like permease family Fez1 PF06818.15 CAM38503.2 - 0.0058 17.1 21.2 0.047 14.1 12.6 3.4 2 1 1 3 3 3 3 Fez1 MIP-T3_C PF17749.1 CAM38503.2 - 1.5 8.8 6.6 0.64 10.0 2.8 2.4 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Exonuc_VII_L PF02601.15 CAM38503.2 - 8.1 5.9 10.2 1.1 8.8 5.2 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit Pkinase PF00069.25 CAM38504.1 - 2.3e-55 187.8 0.0 3.3e-55 187.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM38504.1 - 5.1e-31 107.9 0.0 9e-31 107.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM38504.1 - 0.0017 17.7 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Glyco_hydro_4C PF11975.8 CAM38504.1 - 0.045 13.8 0.1 0.085 12.9 0.1 1.5 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain Orthopox_A5L PF06193.11 CAM38504.1 - 0.085 12.3 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like Pkinase_fungal PF17667.1 CAM38504.1 - 0.12 11.2 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase ubiquitin PF00240.23 CAM38508.1 - 4e-16 58.5 0.0 4.5e-16 58.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CAM38508.1 - 4.5e-07 29.6 0.0 4.9e-07 29.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 CAM38508.1 - 0.00067 19.7 0.1 0.0015 18.6 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 CAM38508.1 - 0.0035 17.6 0.0 0.0038 17.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_2 PF14560.6 CAM38508.1 - 0.033 14.6 0.0 0.067 13.6 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-like domain DoxX PF07681.12 CAM38509.1 - 0.0014 19.2 6.2 0.0037 17.8 6.2 1.7 1 1 0 1 1 1 1 DoxX HR_lesion PF05514.11 CAM38509.1 - 0.0093 16.1 2.7 0.014 15.6 2.7 1.4 1 1 0 1 1 1 1 HR-like lesion-inducing TctB PF07331.11 CAM38509.1 - 0.53 10.6 9.1 0.69 10.2 8.2 1.7 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family SIR2 PF02146.17 CAM38510.1 - 4.5e-46 157.0 0.0 5.5e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Sir2 family Pkinase PF00069.25 CAM38511.1 - 8.8e-45 153.1 0.0 7.1e-44 150.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM38511.1 - 9.3e-25 87.4 0.0 1e-21 77.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 CAM38511.1 - 0.0081 15.5 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family OGG_N PF07934.12 CAM38513.1 - 1.2e-30 106.1 0.3 2.2e-30 105.2 0.3 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 CAM38513.1 - 3.4e-09 37.1 0.0 4.9e-08 33.4 0.0 2.2 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 CAM38513.1 - 0.0004 20.1 0.0 0.0016 18.2 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif Pkinase PF00069.25 CAM38515.1 - 2e-51 174.9 0.0 4e-26 92.0 0.0 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM38515.1 - 4.9e-28 98.1 0.0 1.1e-15 57.7 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase DSPc PF00782.20 CAM38515.1 - 1.1e-26 93.2 0.0 1.9e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain LRR_8 PF13855.6 CAM38515.1 - 1.4e-11 44.0 7.1 1.4e-09 37.6 3.3 4.1 4 0 0 4 4 4 1 Leucine rich repeat LRR_4 PF12799.7 CAM38515.1 - 1.2e-08 35.1 6.6 0.00021 21.6 0.6 4.1 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) Y_phosphatase PF00102.27 CAM38515.1 - 0.0012 18.5 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Kinase-like PF14531.6 CAM38515.1 - 0.0021 17.4 0.0 0.31 10.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like ZZ PF00569.17 CAM38515.1 - 0.093 12.6 3.4 0.27 11.1 3.4 1.8 1 0 0 1 1 1 0 Zinc finger, ZZ type LRR_1 PF00560.33 CAM38515.1 - 0.68 10.7 5.3 1.9e+02 3.3 0.1 5.6 5 0 0 5 5 5 0 Leucine Rich Repeat zf-UBR PF02207.20 CAM38515.1 - 6.4 7.0 7.7 1.4 9.2 3.8 2.0 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) Thioredoxin PF00085.20 CAM38516.1 - 2.7e-25 88.4 0.0 1.9e-24 85.6 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 CAM38516.1 - 4.6e-08 33.5 0.3 1.9e-06 28.3 0.1 3.2 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CAM38516.1 - 2.5e-05 24.5 0.1 0.0036 17.6 0.0 3.6 4 1 1 5 5 5 1 Thioredoxin-like Redoxin PF08534.10 CAM38516.1 - 0.00036 20.3 0.3 0.0017 18.1 0.0 2.1 2 1 0 2 2 2 1 Redoxin TraF PF13728.6 CAM38516.1 - 0.00092 19.1 0.0 0.0092 15.8 0.0 2.4 3 0 0 3 3 3 1 F plasmid transfer operon protein AhpC-TSA PF00578.21 CAM38516.1 - 0.0015 18.5 0.0 0.006 16.5 0.0 2.0 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_6 PF13848.6 CAM38516.1 - 0.0022 17.9 0.0 0.011 15.7 0.0 2.2 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CAM38516.1 - 0.0024 18.0 0.0 0.0058 16.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 CAM38516.1 - 0.0062 16.3 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 CAM38516.1 - 0.028 13.8 0.0 0.054 12.8 0.0 1.4 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family CbbQ_C PF08406.10 CAM38516.1 - 0.088 13.1 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 CbbQ/NirQ/NorQ C-terminal CAP_N PF01213.19 CAM38517.1 - 9.1 5.7 11.8 1.7 8.1 5.1 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Exo_endo_phos PF03372.23 CAM38518.1 - 9.4e-17 61.3 0.0 1.5e-15 57.3 0.0 2.7 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family zf_PR_Knuckle PF18445.1 CAM38518.1 - 0.43 10.4 3.9 0.13 12.0 0.2 2.1 2 0 0 2 2 2 0 PR zinc knuckle motif DUF2755 PF10954.8 CAM38519.1 - 0.043 13.8 0.9 0.043 13.8 0.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2755) Glyco_hydro_65m PF03632.15 CAM38520.1 - 1.5e-40 139.3 0.0 2.1e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65C PF03633.15 CAM38520.1 - 5.7e-08 32.5 0.1 1.2e-07 31.5 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain Glyco_hydro_65N PF03636.15 CAM38520.1 - 0.0079 15.9 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Kelch_5 PF13854.6 CAM38521.2 - 2.9e-12 46.3 8.9 2e-05 24.5 0.2 5.8 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 CAM38521.2 - 8.8e-12 44.4 4.1 5.5e-05 22.7 0.1 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 CAM38521.2 - 5.3e-11 42.5 17.9 2.1e-06 27.9 0.1 8.0 10 0 0 10 10 10 2 Galactose oxidase, central domain Kelch_4 PF13418.6 CAM38521.2 - 1.6e-10 40.8 13.3 2e-06 27.7 0.1 5.7 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 CAM38521.2 - 7.1e-08 32.5 2.3 0.0057 16.9 0.0 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 CAM38521.2 - 6.9e-06 25.8 7.5 0.52 10.4 0.0 5.5 5 0 0 5 5 5 2 Kelch motif HA2 PF04408.23 CAM38522.1 - 2.6e-16 59.8 0.0 5.8e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CAM38522.1 - 1.4e-11 44.7 0.0 5.2e-11 42.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CAM38522.1 - 1.1e-10 41.7 0.0 4.4e-10 39.8 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 CAM38522.1 - 1e-07 31.9 0.3 2.2e-07 30.8 0.3 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 CAM38522.1 - 3.1e-06 27.6 0.8 5.7e-06 26.7 0.2 1.7 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.6 CAM38522.1 - 2.9e-05 24.4 0.0 7.4e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CAM38522.1 - 0.00047 19.9 0.0 0.00092 19.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CAM38522.1 - 0.0024 17.0 0.0 0.005 15.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.22 CAM38522.1 - 0.0026 17.4 0.2 0.0093 15.6 0.2 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain cobW PF02492.19 CAM38522.1 - 0.0067 16.0 0.3 0.29 10.7 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 CAM38522.1 - 0.0068 15.9 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_25 PF13481.6 CAM38522.1 - 0.015 14.9 0.0 0.035 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 CAM38522.1 - 0.021 14.8 0.2 0.043 13.8 0.2 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_16 PF13191.6 CAM38522.1 - 0.031 14.7 0.1 0.031 14.7 0.1 2.5 4 0 0 4 4 4 0 AAA ATPase domain AAA_23 PF13476.6 CAM38522.1 - 0.038 14.5 0.0 0.065 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CAM38522.1 - 0.041 13.6 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ResIII PF04851.15 CAM38522.1 - 0.042 13.8 0.0 3.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NACHT PF05729.12 CAM38522.1 - 0.048 13.6 0.1 0.31 11.0 0.1 2.3 2 1 0 2 2 2 0 NACHT domain Dynamin_N PF00350.23 CAM38523.1 - 3.2e-15 56.6 0.0 5.9e-14 52.5 0.0 2.4 1 1 0 1 1 1 1 Dynamin family DUF5600 PF18150.1 CAM38523.1 - 4.8e-12 46.4 0.0 9.8e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) MMR_HSR1 PF01926.23 CAM38523.1 - 1.1e-07 31.9 0.0 2.9e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EHD_N PF16880.5 CAM38523.1 - 1.1e-06 28.3 0.0 2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 N-terminal EH-domain containing protein RsgA_GTPase PF03193.16 CAM38523.1 - 0.11 12.4 0.0 2.5 8.0 0.0 2.6 3 0 0 3 3 3 0 RsgA GTPase Cofilin_ADF PF00241.20 CAM38525.1 - 1.1e-17 63.9 0.0 2.8e-11 43.3 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein MMgT PF10270.9 CAM38528.1 - 0.0061 16.9 0.2 0.0093 16.3 0.2 1.4 1 1 0 1 1 1 1 Membrane magnesium transporter Clat_adaptor_s PF01217.20 CAM38529.1 - 8.6e-51 171.6 4.2 9.5e-51 171.5 4.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain tRNA-synt_2 PF00152.20 CAM38530.1 - 3.5e-87 292.4 0.0 4.9e-87 291.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_synt_1c_R1 PF04558.15 CAM38530.1 - 9.1e-34 116.8 0.5 1.5e-33 116.1 0.5 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_anti-codon PF01336.25 CAM38530.1 - 8.7e-10 38.4 0.0 2e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF1412 PF07203.11 CAM38531.1 - 0.2 11.9 0.1 0.35 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1412) CBFD_NFYB_HMF PF00808.23 CAM38533.1 - 1.2e-05 25.5 0.5 2e-05 24.8 0.5 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CAM38533.1 - 0.00016 22.0 0.5 0.00027 21.3 0.1 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 DUF1931 PF09123.11 CAM38533.1 - 0.15 12.2 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) EF-hand_7 PF13499.6 CAM38535.1 - 1.7e-23 82.8 5.6 2.1e-15 56.9 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CAM38535.1 - 4.3e-21 72.8 9.9 1.8e-07 30.2 1.4 3.6 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CAM38535.1 - 4.2e-19 66.8 3.5 3.5e-06 26.5 0.1 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 CAM38535.1 - 1.2e-14 53.8 7.9 1.8e-11 43.7 0.8 3.3 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 CAM38535.1 - 2.5e-13 50.1 0.2 1.4e-06 28.6 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CAM38535.1 - 1.5e-12 46.4 4.9 0.00032 20.1 1.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 CAM38535.1 - 1.4e-06 28.2 0.8 0.0048 16.8 0.2 2.2 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 CAM38535.1 - 0.00087 19.3 0.0 0.31 10.9 0.0 3.0 2 1 1 3 3 3 1 Caleosin related protein DUF3164 PF11363.8 CAM38535.1 - 0.0058 16.3 0.2 0.072 12.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3164) EF-hand_14 PF17959.1 CAM38535.1 - 0.0079 16.5 3.3 0.35 11.3 0.3 2.3 1 1 0 2 2 2 1 EF-hand domain TerB PF05099.13 CAM38535.1 - 0.014 15.3 5.8 0.11 12.5 1.1 2.4 1 1 2 3 3 3 0 Tellurite resistance protein TerB MgtE_N PF03448.17 CAM38535.1 - 0.032 14.8 0.7 0.032 14.8 0.7 2.5 3 0 0 3 3 3 0 MgtE intracellular N domain SPARC_Ca_bdg PF10591.9 CAM38535.1 - 0.081 13.2 1.9 1 9.7 0.4 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 CAM38535.1 - 0.083 13.1 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 Dockerin type I domain EF-hand_11 PF08976.11 CAM38535.1 - 0.13 13.1 0.5 0.42 11.5 0.1 1.9 2 0 0 2 2 2 0 EF-hand domain SurA_N_2 PF13623.6 CAM38535.1 - 0.13 12.1 5.2 1 9.2 0.6 2.4 1 1 1 2 2 2 0 SurA N-terminal domain DUF3911 PF13050.6 CAM38535.1 - 0.54 10.4 3.2 2.7 8.1 0.2 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3911) Aminotran_4 PF01063.19 CAM38537.1 - 3.4e-35 121.9 0.0 4.3e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Glycos_transf_1 PF00534.20 CAM38538.1 - 2.4e-27 95.6 0.1 7.1e-27 94.0 0.0 1.8 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CAM38538.1 - 3.2e-14 53.5 0.1 6.2e-13 49.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CAM38538.1 - 8.9e-06 25.8 0.0 1.8e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 CAM38538.1 - 0.0034 17.8 0.0 0.0081 16.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 DnaJ PF00226.31 CAM38539.1 - 6.1e-19 67.9 0.2 1.7e-18 66.5 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.28 CAM38539.1 - 3.4e-14 52.0 15.9 0.0011 18.7 0.0 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 CAM38539.1 - 9.6e-11 41.0 24.2 0.0022 18.0 0.3 7.4 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 CAM38539.1 - 2.4e-07 30.4 11.6 0.06 13.6 0.1 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 CAM38539.1 - 9.3e-05 22.5 0.4 22 5.7 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 CAM38539.1 - 0.0024 18.5 11.5 5.4 7.8 0.2 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 CAM38539.1 - 0.0026 18.0 13.5 0.004 17.4 0.5 5.0 3 2 4 7 7 7 2 Tetratricopeptide repeat Rapsyn_N PF10579.9 CAM38539.1 - 0.0032 17.5 0.3 1.4 9.0 0.0 3.1 2 1 1 3 3 3 1 Rapsyn N-terminal myristoylation and linker region TPR_11 PF13414.6 CAM38539.1 - 0.035 13.8 0.5 12 5.7 0.3 4.1 4 0 0 4 4 4 0 TPR repeat TPR_6 PF13174.6 CAM38539.1 - 0.055 14.1 8.8 14 6.6 0.1 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CAM38539.1 - 0.096 12.9 13.4 0.39 11.0 0.4 4.5 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CAM38539.1 - 0.48 10.6 11.7 3 8.1 0.1 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 CAM38539.1 - 1.6 8.9 6.7 1.5 9.0 0.7 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat Sec7 PF01369.20 CAM38541.1 - 5.6e-47 159.8 0.0 1.4e-46 158.5 0.0 1.6 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.7 CAM38541.1 - 1.1e-05 25.4 0.0 4.7e-05 23.3 0.0 2.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal GTP_EFTU PF00009.27 CAM38542.2 - 2e-07 30.7 0.0 8.2e-07 28.7 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 CAM38542.2 - 0.01 15.5 0.5 0.27 11.0 0.3 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 CAM38542.2 - 0.011 15.5 2.7 0.36 10.6 0.5 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein GTP_EFTU_D2 PF03144.25 CAM38542.2 - 0.022 15.1 0.6 0.061 13.7 0.2 2.0 2 0 0 2 2 2 0 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 CAM38542.2 - 0.024 14.6 0.4 1.5 8.7 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 CAM38542.2 - 0.15 12.6 0.1 0.44 11.1 0.0 1.8 2 0 0 2 2 2 0 ABC transporter Ribosomal_L35Ae PF01247.18 CAM38543.1 - 6.6e-33 112.7 0.8 1.1e-32 112.1 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 CAM38543.1 - 2.2e-05 24.6 0.3 0.056 13.7 0.0 2.4 2 1 0 2 2 2 2 RimM N-terminal domain HlyIII PF03006.20 CAM38544.1 - 0.0047 16.7 0.6 0.0058 16.4 0.6 1.0 1 0 0 1 1 1 1 Haemolysin-III related TarH PF02203.15 CAM38545.1 - 0.039 13.9 0.1 0.068 13.1 0.1 1.4 1 0 0 1 1 1 0 Tar ligand binding domain homologue Trp_oprn_chp PF09534.10 CAM38545.1 - 0.082 12.7 3.8 0.16 11.8 3.8 1.5 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) CENP-F_leu_zip PF10473.9 CAM38547.1 - 0.0035 17.4 18.2 0.0035 17.4 18.2 8.1 3 2 3 7 7 7 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 CAM38547.1 - 0.0066 16.7 25.7 0.0066 16.7 25.7 9.1 3 2 6 9 9 9 2 Autophagy protein 16 (ATG16) LRR_6 PF13516.6 CAM38548.1 - 5.8e-08 32.2 1.4 0.09 12.9 0.0 4.3 5 0 0 5 5 5 3 Leucine Rich repeat PLRV_ORF5 PF01690.17 CAM38548.1 - 0.057 12.2 2.5 0.075 11.8 2.5 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein ANAPC4_WD40 PF12894.7 CAM38549.1 - 0.00032 20.9 0.0 1.8 8.9 0.0 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CAM38549.1 - 0.05 14.5 4.7 6.4 7.8 0.1 3.9 3 0 0 3 3 3 0 WD domain, G-beta repeat PP2C PF00481.21 CAM38550.1 - 5.5e-54 183.5 0.0 7.4e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CAM38550.1 - 6.7e-05 22.6 0.0 0.00014 21.5 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 CAM38551.1 - 3.8e-55 187.3 0.0 5e-55 186.9 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CAM38551.1 - 0.038 13.6 0.0 0.079 12.6 0.0 1.6 1 1 0 1 1 1 0 Protein phosphatase 2C Sec7 PF01369.20 CAM38552.1 - 2.9e-49 167.2 0.0 8.9e-49 165.6 0.0 1.8 2 0 0 2 2 2 1 Sec7 domain DUF1981 PF09324.10 CAM38552.1 - 1.1e-18 66.9 0.1 2.7e-18 65.6 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1981) Sec7_N PF12783.7 CAM38552.1 - 4.2e-18 65.7 2.2 7.2e-18 65.0 0.3 2.4 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Urb2 PF10441.9 CAM38552.1 - 4.7 7.1 5.7 91 2.9 0.2 4.6 5 0 0 5 5 5 0 Urb2/Npa2 family Fez1 PF06818.15 CAM38553.1 - 0.28 11.6 164.8 0.06 13.8 16.8 8.5 2 2 5 7 7 7 0 Fez1 TLV_coat PF00429.19 CAM38553.1 - 0.54 8.9 1.5 1 8.0 1.5 1.3 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) Mod_r PF07200.13 CAM38553.1 - 8.8 6.4 152.0 0.11 12.5 25.6 9.3 3 2 7 10 10 10 0 Modifier of rudimentary (Mod(r)) protein CENP-F_leu_zip PF10473.9 CAM38554.2 - 8.9e-25 87.3 363.4 0.0071 16.4 23.1 16.0 6 3 11 17 17 17 16 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HIP1_clath_bdg PF16515.5 CAM38554.2 - 4.3e-14 52.9 329.2 0.099 13.3 10.9 20.6 6 3 21 27 27 27 24 Clathrin-binding domain of Huntingtin-interacting protein 1 Atg14 PF10186.9 CAM38554.2 - 0.0011 18.2 9.6 0.0011 18.2 9.6 10.8 2 2 7 9 9 9 7 Vacuolar sorting 38 and autophagy-related subunit 14 Fez1 PF06818.15 CAM38554.2 - 0.0016 19.0 295.7 0.097 13.1 43.3 10.5 2 2 9 11 11 11 8 Fez1 CENP-F_leu_zip PF10473.9 CAM38555.2 - 1.4e-17 64.1 239.6 0.014 15.5 19.9 13.1 8 5 5 13 13 13 12 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HIP1_clath_bdg PF16515.5 CAM38555.2 - 9.4e-13 48.6 209.7 0.084 13.5 10.9 15.0 8 5 8 16 16 16 14 Clathrin-binding domain of Huntingtin-interacting protein 1 Fez1 PF06818.15 CAM38555.2 - 3.8e-05 24.2 188.5 0.013 15.9 25.3 8.0 3 2 4 8 8 8 5 Fez1 TnpB_IS66 PF05717.13 CAM38555.2 - 0.00026 20.8 0.0 16 5.5 0.0 6.4 5 1 1 6 6 6 1 IS66 Orf2 like protein Atg14 PF10186.9 CAM38555.2 - 0.00056 19.1 133.6 0.042 12.9 16.8 7.9 2 2 4 6 6 6 5 Vacuolar sorting 38 and autophagy-related subunit 14 PHM7_ext PF12621.8 CAM38555.2 - 0.0047 17.1 0.9 4.6 7.5 0.1 3.1 2 0 0 2 2 2 2 Extracellular tail, of 10TM putative phosphate transporter Mod_r PF07200.13 CAM38555.2 - 0.051 13.7 199.9 0.057 13.5 24.2 10.9 3 3 10 13 13 13 0 Modifier of rudimentary (Mod(r)) protein CENP-F_leu_zip PF10473.9 CAM38556.1 - 1.2e-07 31.9 192.4 0.00052 20.0 10.3 12.3 9 2 4 13 13 13 9 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HIP1_clath_bdg PF16515.5 CAM38556.1 - 0.0006 20.4 171.5 0.02 15.5 9.8 13.4 9 2 4 14 14 14 9 Clathrin-binding domain of Huntingtin-interacting protein 1 Rootletin PF15035.6 CAM38556.1 - 0.0079 16.2 4.1 0.0079 16.2 4.1 9.6 4 3 3 7 7 7 1 Ciliary rootlet component, centrosome cohesion NIL PF09383.10 CAM38556.1 - 2.6 8.0 12.3 38 4.2 0.2 5.8 4 1 0 4 4 4 0 NIL domain APG6_N PF17675.1 CAM38556.1 - 3.6 8.1 243.0 0.037 14.6 16.5 12.4 9 2 3 12 12 12 0 Apg6 coiled-coil region Lebercilin PF15619.6 CAM38557.1 - 5.1e-05 23.0 19.2 5.1e-05 23.0 19.2 7.1 5 1 2 7 7 7 2 Ciliary protein causing Leber congenital amaurosis disease C2 PF00168.30 CAM38557.1 - 0.00075 19.8 0.0 0.0019 18.5 0.0 1.7 1 0 0 1 1 1 1 C2 domain Fez1 PF06818.15 CAM38557.1 - 0.0028 18.1 25.2 0.0028 18.1 25.2 5.1 3 2 2 5 5 5 2 Fez1 DHR10 PF18595.1 CAM38557.1 - 0.01 15.9 16.1 0.01 15.9 16.1 8.0 5 3 2 7 7 7 0 Designed helical repeat protein 10 domain TMF_DNA_bd PF12329.8 CAM38557.1 - 0.011 15.7 9.4 0.011 15.7 9.4 10.7 8 4 1 10 10 10 0 TATA element modulatory factor 1 DNA binding Shugoshin_N PF07558.11 CAM38557.1 - 0.017 15.0 30.5 0.082 12.8 0.2 8.7 8 1 1 9 9 9 0 Shugoshin N-terminal coiled-coil region Surfac_D-trimer PF09006.11 CAM38557.1 - 3.6 7.5 5.8 3.7 7.5 0.2 3.6 4 0 0 4 4 4 0 Lung surfactant protein D coiled-coil trimerisation Pox_A_type_inc PF04508.12 CAM38557.1 - 7.3 6.6 39.0 0.43 10.5 0.5 8.7 10 0 0 10 10 10 0 Viral A-type inclusion protein repeat HOOK PF05622.12 CAM38557.1 - 7.8 4.5 77.5 0.011 14.0 12.9 4.7 1 1 2 4 4 4 0 HOOK protein Cauli_AT PF03233.13 CAM38558.1 - 0.04 13.8 0.4 0.11 12.4 0.4 1.7 1 0 0 1 1 1 0 Aphid transmission protein Thiamine_BP PF01910.17 CAM38558.1 - 0.39 10.7 5.0 7 6.6 0.5 3.1 2 0 0 2 2 2 0 Thiamine-binding protein Macoilin PF09726.9 CAM38558.1 - 0.69 8.4 58.7 0.16 10.5 11.3 4.5 2 1 2 4 4 4 0 Macoilin family Corona_S2 PF01601.16 CAM38559.1 - 0.041 12.4 4.0 0.024 13.2 1.4 1.8 1 1 1 2 2 2 0 Coronavirus S2 glycoprotein DNA_photolyase PF00875.18 CAM38559.1 - 7.3 6.6 10.9 1.3 9.0 0.1 3.4 3 0 0 3 3 3 0 DNA photolyase Alba PF01918.21 CAM38560.1 - 5.2e-17 61.4 0.4 8.2e-17 60.8 0.4 1.3 1 0 0 1 1 1 1 Alba Rpp20 PF12328.8 CAM38560.1 - 0.0016 18.4 0.4 0.0036 17.2 0.4 1.6 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P RhlB PF12300.8 CAM38560.1 - 1.7 8.7 16.2 0.21 11.7 11.2 1.9 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB Adap_comp_sub PF00928.21 CAM38561.2 - 2.6e-57 194.2 0.0 3.2e-57 193.9 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CAM38561.2 - 0.00025 21.0 0.2 0.00044 20.2 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ACBP PF00887.19 CAM38562.1 - 8.3e-17 61.2 1.5 9.4e-17 61.0 1.5 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein TIP49 PF06068.13 CAM38563.1 - 5.1e-158 525.9 1.5 1.2e-157 524.6 0.6 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain TIP49_C PF17856.1 CAM38563.1 - 4.6e-25 87.5 1.8 6.1e-25 87.1 0.7 1.9 2 0 0 2 2 1 1 TIP49 AAA-lid domain AAA PF00004.29 CAM38563.1 - 1.3e-08 35.3 2.0 8e-06 26.3 0.1 3.1 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CAM38563.1 - 1.9e-07 31.0 0.6 0.00017 21.3 0.1 2.9 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 CAM38563.1 - 1e-05 25.0 0.2 2.1e-05 24.0 0.2 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 CAM38563.1 - 1.5e-05 25.5 0.1 8.6e-05 23.0 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CAM38563.1 - 2.2e-05 24.8 0.2 0.16 12.3 0.0 2.8 1 1 0 2 2 2 2 AAA domain AAA_5 PF07728.14 CAM38563.1 - 4.4e-05 23.5 0.2 0.0099 15.9 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CAM38563.1 - 5.8e-05 22.6 1.3 0.0011 18.4 0.6 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 CAM38563.1 - 0.00011 22.6 4.1 0.00057 20.2 1.5 2.6 2 1 0 2 2 1 1 AAA domain Zeta_toxin PF06414.12 CAM38563.1 - 0.0032 16.8 0.3 0.0077 15.5 0.3 1.6 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.26 CAM38563.1 - 0.0033 17.2 0.0 1.4 8.6 0.1 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_17 PF13207.6 CAM38563.1 - 0.0037 17.7 0.1 0.028 14.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain CPT PF07931.12 CAM38563.1 - 0.007 16.2 0.4 0.028 14.3 0.1 2.3 2 1 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein ATPase PF06745.13 CAM38563.1 - 0.0083 15.5 0.2 0.02 14.3 0.2 1.7 1 0 0 1 1 1 1 KaiC AAA_28 PF13521.6 CAM38563.1 - 0.016 15.5 0.1 0.034 14.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CAM38563.1 - 0.027 14.2 0.2 0.089 12.5 0.2 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 CAM38563.1 - 0.027 14.4 0.0 0.088 12.7 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 CAM38563.1 - 0.029 13.9 0.1 0.092 12.3 0.1 1.8 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 CAM38563.1 - 0.042 13.1 0.0 0.075 12.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) GATase PF00117.28 CAM38563.1 - 0.049 13.4 0.1 0.83 9.4 0.0 2.2 2 0 0 2 2 2 0 Glutamine amidotransferase class-I Sigma54_activ_2 PF14532.6 CAM38563.1 - 0.049 13.7 0.0 0.61 10.2 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 CAM38563.1 - 0.067 12.7 0.4 0.25 10.8 0.1 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 CAM38563.1 - 0.081 13.4 0.2 0.18 12.3 0.2 1.6 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 CAM38563.1 - 0.1 12.4 0.2 0.57 10.0 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain TsaE PF02367.17 CAM38563.1 - 0.1 12.6 0.1 0.31 11.1 0.1 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TFIID-31kDa PF02291.15 CAM38563.1 - 0.1 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Suv3_C_1 PF18147.1 CAM38564.1 - 8.2e-09 35.2 2.0 2.8e-08 33.5 0.4 2.7 3 0 0 3 3 3 1 Suv3 C-terminal domain 1 SUV3_C PF12513.8 CAM38564.1 - 9.8e-09 35.0 0.1 2.5e-08 33.7 0.1 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 CAM38564.1 - 0.00021 21.6 0.0 0.0018 18.6 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CAM38564.1 - 0.026 14.3 0.0 0.16 11.7 0.0 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase Kinesin PF00225.23 CAM38564.1 - 0.15 11.0 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Kinesin motor domain PhoLip_ATPase_C PF16212.5 CAM38565.1 - 3.4e-43 148.2 22.4 3.4e-43 148.2 22.4 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CAM38565.1 - 1.2e-23 82.5 0.3 3.1e-23 81.2 0.3 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CAM38565.1 - 2.8e-12 47.4 1.4 4.7e-06 27.0 2.3 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CAM38565.1 - 2.2e-09 37.3 0.0 5.9e-08 32.7 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CAM38565.1 - 0.00041 19.9 4.2 0.0011 18.6 0.0 2.9 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CAM38565.1 - 0.0018 18.1 0.0 0.0033 17.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CAM38565.1 - 0.0076 16.7 0.0 7.8 6.8 0.1 2.9 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CAM38565.1 - 0.19 11.9 0.0 0.56 10.4 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF21 PF01595.20 CAM38567.1 - 1.2e-33 116.3 0.3 2.6e-33 115.2 0.3 1.5 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 CAM38567.1 - 3.1e-06 27.5 0.1 0.0054 17.1 0.0 2.5 2 0 0 2 2 2 2 CBS domain cNMP_binding PF00027.29 CAM38567.1 - 0.0074 16.3 0.0 0.021 14.9 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain MHYT PF03707.16 CAM38567.1 - 2.3 8.5 6.7 7.1 6.9 0.6 2.6 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat Vps52 PF04129.12 CAM38568.2 - 8.9e-14 51.1 5.5 6.1e-12 45.1 4.7 2.2 2 0 0 2 2 2 2 Vps52 / Sac2 family COG2 PF06148.11 CAM38568.2 - 0.095 12.8 1.9 0.35 11.0 1.9 2.0 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 FAD_binding_1 PF00667.20 CAM38569.1 - 4.7e-31 108.1 0.0 6.8e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CAM38569.1 - 7.9e-24 84.5 0.0 1.5e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 CAM38569.1 - 1.5e-14 54.6 0.0 2.9e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain WD40 PF00400.32 CAM38570.1 - 2.2e-15 56.8 2.9 0.00096 19.9 0.3 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM38570.1 - 9.7e-06 25.8 0.1 0.0066 16.7 0.1 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain DUF2478 PF10649.9 CAM38571.2 - 0.021 14.4 0.1 0.044 13.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2478) RRM_1 PF00076.22 CAM38572.1 - 1.3e-11 44.1 0.0 2.5e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.8 CAM38572.1 - 0.0027 18.1 0.3 0.0061 17.0 0.1 1.6 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G Orthopox_C10L PF07020.11 CAM38572.1 - 0.11 13.3 0.1 0.18 12.5 0.1 1.4 1 0 0 1 1 1 0 Orthopoxvirus C10L protein Methyltransf_11 PF08241.12 CAM38576.1 - 7.7e-09 36.1 0.0 0.0055 17.3 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain WBS_methylT PF12589.8 CAM38576.1 - 1.5e-08 35.3 14.7 4e-08 33.9 14.7 1.8 1 1 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_25 PF13649.6 CAM38576.1 - 7e-07 29.9 0.0 0.0026 18.4 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 CAM38576.1 - 0.00033 21.3 0.0 0.052 14.3 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAM38576.1 - 0.0013 18.6 0.0 0.052 13.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAM38576.1 - 0.0037 17.1 0.0 0.0051 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Transket_pyr PF02779.24 CAM38576.1 - 0.098 12.3 0.1 7.6 6.2 0.1 2.4 2 0 0 2 2 2 0 Transketolase, pyrimidine binding domain Metallophos PF00149.28 CAM38579.2 - 3.4e-16 60.4 0.0 2.6e-12 47.7 0.0 3.5 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase DUF3220 PF11516.8 CAM38579.2 - 0.1 12.8 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) Ribosomal_S19e PF01090.19 CAM38580.1 - 2.7e-43 147.0 0.0 3.1e-43 146.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Mrr_N PF14338.6 CAM38580.1 - 0.0086 16.2 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 Mrr N-terminal domain SRP68 PF16969.5 CAM38581.1 - 1.2e-52 179.7 12.8 5.2e-43 147.9 11.8 3.0 1 1 1 2 2 2 2 RNA-binding signal recognition particle 68 TPR_2 PF07719.17 CAM38581.1 - 0.03 14.4 3.0 0.082 13.1 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_21 PF09976.9 CAM38581.1 - 0.18 11.5 2.8 1 9.0 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_12 PF13424.6 CAM38581.1 - 1.6 9.0 5.5 0.31 11.4 0.3 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_16 PF13191.6 CAM38582.1 - 0.0039 17.6 0.2 0.012 15.9 0.1 1.8 2 0 0 2 2 2 1 AAA ATPase domain Amastin PF07344.11 CAM38583.1 - 8.6e-55 184.8 11.8 1.1e-54 184.5 11.8 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein AAA_16 PF13191.6 CAM38584.1 - 0.068 13.5 0.3 0.26 11.6 0.2 2.2 2 1 0 2 2 2 0 AAA ATPase domain Amastin PF07344.11 CAM38585.1 - 2.9e-49 166.9 12.0 3.6e-49 166.6 12.0 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein AAA_16 PF13191.6 CAM38586.2 - 0.075 13.4 0.2 0.25 11.7 0.2 2.1 1 1 0 1 1 1 0 AAA ATPase domain Amastin PF07344.11 CAM38587.1 - 1.4e-50 171.1 13.8 1.8e-50 170.8 13.8 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF3624 PF12292.8 CAM38588.1 - 0.075 13.5 0.2 0.16 12.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3624) Peptidase_M14 PF00246.24 CAM38589.1 - 1.8e-19 70.7 0.0 6.4e-19 68.8 0.0 1.9 1 1 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 CAM38589.1 - 2.4e-07 31.1 0.1 5.3e-07 30.0 0.1 1.6 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain AstE_AspA PF04952.14 CAM38589.1 - 0.00013 21.2 0.0 0.00023 20.3 0.0 1.5 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family cNMP_binding PF00027.29 CAM38590.1 - 2.2e-22 79.0 0.1 2.8e-11 43.3 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 CAM38590.1 - 0.072 12.8 0.0 0.71 9.6 0.0 2.4 2 0 0 2 2 2 0 Cupin domain GTP_EFTU PF00009.27 CAM38590.1 - 0.18 11.3 2.7 0.14 11.7 0.6 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Urm1 PF09138.11 CAM38591.1 - 3.4e-25 88.2 0.0 3.9e-25 88.0 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 CAM38591.1 - 9.7e-08 32.5 0.1 1.3e-07 32.2 0.1 1.2 1 0 0 1 1 1 1 ThiS family TGS PF02824.21 CAM38591.1 - 0.067 13.2 0.2 0.19 11.8 0.1 1.7 2 0 0 2 2 2 0 TGS domain GTP_EFTU PF00009.27 CAM38592.1 - 1e-27 97.0 0.0 1.6e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CAM38592.1 - 2.4e-07 30.8 0.0 5.7e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CAM38592.1 - 1.8e-05 25.1 0.3 4e-05 23.9 0.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SRPRB PF09439.10 CAM38592.1 - 0.00061 19.3 0.3 0.012 15.1 0.1 2.5 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit cobW PF02492.19 CAM38592.1 - 0.0031 17.1 3.7 0.0079 15.8 0.4 2.9 2 1 1 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 CAM38592.1 - 0.0051 16.6 0.1 3 7.6 0.0 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 CAM38592.1 - 0.021 15.2 0.1 0.074 13.4 0.1 1.9 2 0 0 2 2 2 0 AAA ATPase domain ATP_bind_1 PF03029.17 CAM38592.1 - 0.15 11.8 0.1 1.9 8.2 0.0 2.6 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein SAS4 PF15460.6 CAM38593.1 - 0.062 13.4 0.0 0.084 13.0 0.0 1.2 1 0 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 Patatin PF01734.22 CAM38595.1 - 2e-08 34.7 1.8 1.3e-07 32.0 1.8 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase Phage_holin_2_4 PF16082.5 CAM38596.1 - 0.072 12.8 0.0 0.15 11.8 0.0 1.5 1 1 1 2 2 2 0 Bacteriophage holin family, superfamily II-like Thioredoxin PF00085.20 CAM38597.1 - 0.0056 16.6 0.0 0.0097 15.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DUF844 PF05815.11 CAM38597.1 - 0.11 11.7 0.1 0.13 11.4 0.1 1.1 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) EF-hand_8 PF13833.6 CAM38599.1 - 1.3e-10 41.0 0.1 8.2e-08 32.0 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.6 CAM38599.1 - 9.2e-10 38.8 0.0 0.0017 18.7 0.0 4.1 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 CAM38599.1 - 1.4e-09 37.1 0.1 0.00037 20.2 0.0 5.9 6 1 1 7 7 7 2 EF-hand domain EF-hand_5 PF13202.6 CAM38599.1 - 1.5e-09 36.9 2.4 0.011 15.1 0.0 5.1 5 0 0 5 5 5 2 EF hand EF-hand_1 PF00036.32 CAM38599.1 - 4.1e-09 35.3 0.0 0.00011 21.4 0.0 4.5 6 0 0 6 6 6 2 EF hand Rab5ip PF07019.12 CAM38600.1 - 0.077 13.6 0.0 0.15 12.7 0.0 1.5 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) Spc7 PF08317.11 CAM38601.1 - 0.00062 18.7 11.2 0.00087 18.3 11.2 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF4618 PF15397.6 CAM38601.1 - 0.12 11.8 13.2 0.9 8.9 13.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) CHDCT2 PF08074.11 CAM38601.1 - 0.14 12.3 6.4 3.1 8.0 6.6 2.0 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain ADIP PF11559.8 CAM38601.1 - 4.9 7.2 17.1 17 5.5 17.1 1.8 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 CAM38601.1 - 5.9 6.7 16.3 1.8 8.4 5.0 2.7 1 1 1 2 2 2 0 Septum formation initiator SlyX PF04102.12 CAM38601.1 - 8.8 7.0 12.0 2.9 8.6 3.1 3.3 1 1 2 3 3 3 0 SlyX NDK PF00334.19 CAM38602.1 - 5.3e-15 55.6 0.0 1.6e-13 50.9 0.0 2.3 2 0 0 2 2 2 1 Nucleoside diphosphate kinase DUF1126 PF06565.12 CAM38602.1 - 0.0023 17.7 0.0 0.0058 16.4 0.0 1.6 1 1 0 1 1 1 1 DUF1126 PH-like domain LRR_6 PF13516.6 CAM38603.1 - 0.075 13.1 0.2 0.26 11.4 0.0 2.0 2 0 0 2 2 2 0 Leucine Rich repeat ATF7IP_BD PF16788.5 CAM38603.1 - 0.15 12.1 1.8 0.23 11.6 1.8 1.2 1 0 0 1 1 1 0 ATF-interacting protein binding domain GEMIN8 PF15348.6 CAM38603.1 - 0.34 11.2 4.2 0.49 10.7 4.2 1.1 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Rhodanese PF00581.20 CAM38605.1 - 9.7e-12 45.4 0.0 1.8e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Aldolase PF01081.19 CAM38605.1 - 0.15 11.4 0.0 4.1 6.8 0.0 2.1 2 0 0 2 2 2 0 KDPG and KHG aldolase Pkinase PF00069.25 CAM38606.2 - 2.5e-19 69.7 0.0 1.8e-18 66.9 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_fungal PF17667.1 CAM38606.2 - 0.0082 15.0 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CAM38606.2 - 0.064 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RMP PF14996.6 CAM38607.1 - 2e-09 37.8 8.9 4.6e-08 33.4 5.6 3.1 2 1 0 2 2 2 1 Retinal Maintenance Beta_helix PF13229.6 CAM38608.2 - 0.0026 17.6 0.0 0.084 12.7 0.0 2.2 2 0 0 2 2 2 1 Right handed beta helix region IucA_IucC PF04183.12 CAM38608.2 - 0.065 12.8 0.3 0.22 11.0 0.2 1.8 2 0 0 2 2 2 0 IucA / IucC family Adeno_E1B_55K PF01696.17 CAM38608.2 - 0.13 10.9 2.8 0.062 12.0 0.4 1.5 2 0 0 2 2 2 0 Adenovirus EB1 55K protein / large t-antigen Cyt-b5 PF00173.28 CAM38609.1 - 1.1e-06 28.6 0.1 2.1e-06 27.8 0.1 1.5 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Mito_carr PF00153.27 CAM38610.1 - 8e-46 153.9 4.6 1.5e-22 79.3 0.2 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein GrlR PF16518.5 CAM38611.1 - 0.021 14.8 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 T3SS negative regulator,GrlR SWIM PF04434.17 CAM38611.1 - 4.2 7.1 8.7 1 9.1 3.5 2.3 2 0 0 2 2 2 0 SWIM zinc finger DNA_pol_A_exo1 PF01612.20 CAM38612.1 - 1.6e-36 125.6 0.4 3.1e-36 124.7 0.4 1.5 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 CAM38612.1 - 1.7e-20 73.5 0.4 7.1e-20 71.5 0.0 2.3 3 0 0 3 3 3 1 PMC2NT (NUC016) domain HRDC PF00570.23 CAM38612.1 - 3.6e-09 36.5 0.0 8.3e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 HRDC domain 2_5_RNA_ligase2 PF13563.6 CAM38612.1 - 0.033 14.1 0.6 0.22 11.4 0.2 2.6 3 0 0 3 3 3 0 2'-5' RNA ligase superfamily Pup PF05639.11 CAM38612.1 - 5 8.1 6.0 0.89 10.5 0.1 2.5 2 0 0 2 2 2 0 Pup-like protein PIP5K PF01504.18 CAM38613.1 - 3.4e-68 229.8 0.0 1.1e-67 228.2 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Sec15 PF04091.12 CAM38613.1 - 0.11 11.9 0.2 0.2 11.0 0.2 1.3 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like AAA_33 PF13671.6 CAM38615.1 - 2.1e-11 44.2 0.0 3.1e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CAM38615.1 - 0.00029 21.1 0.1 0.00083 19.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 CAM38615.1 - 0.00093 18.7 0.1 0.0012 18.3 0.1 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_14 PF13173.6 CAM38615.1 - 0.0015 18.6 0.0 0.0023 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain BORCS8 PF10167.9 CAM38615.1 - 0.0024 17.8 0.1 0.0044 17.0 0.1 1.4 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 8 AAA_18 PF13238.6 CAM38615.1 - 0.0075 16.8 1.0 0.02 15.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CAM38615.1 - 0.011 15.1 0.0 0.018 14.3 0.0 1.6 1 1 0 1 1 1 0 Zeta toxin AAA_5 PF07728.14 CAM38615.1 - 0.056 13.4 0.0 0.12 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Ctr PF04145.15 CAM38615.1 - 0.15 12.7 0.0 0.18 12.5 0.0 1.2 1 0 0 1 1 1 0 Ctr copper transporter family TPT PF03151.16 CAM38616.1 - 1.4e-07 31.2 25.3 1.8e-07 30.8 25.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CAM38616.1 - 6.7e-05 23.1 39.4 0.0029 17.8 19.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family Phage_holin_2_4 PF16082.5 CAM38616.1 - 0.056 13.2 0.0 0.45 10.3 0.0 2.2 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like WW PF00397.26 CAM38618.1 - 0.022 14.9 2.7 0.024 14.7 0.8 2.1 2 0 0 2 2 2 0 WW domain zf-CCHC PF00098.23 CAM38618.1 - 0.05 13.7 4.1 0.05 13.7 4.1 3.7 4 0 0 4 4 4 0 Zinc knuckle zinc-ribbons_6 PF07191.12 CAM38618.1 - 0.53 10.3 18.0 0.85 9.6 11.3 2.9 2 1 0 2 2 2 0 zinc-ribbons EBP50_C PF09007.11 CAM38618.1 - 1.9 9.5 12.9 2.8 8.9 4.8 2.2 2 0 0 2 2 2 0 EBP50, C-terminal DNA_pol_phi PF04931.13 CAM38618.1 - 3.5 5.6 6.5 4.5 5.3 6.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF3239 PF11580.8 CAM38619.2 - 0.082 13.2 0.1 0.17 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3239) CesT PF05932.13 CAM38621.1 - 1.6e-11 44.4 0.5 3.9e-11 43.1 0.5 1.7 1 0 0 1 1 1 1 Tir chaperone protein (CesT) family ubiquitin PF00240.23 CAM38621.1 - 0.0021 17.8 0.0 0.032 14.0 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 CAM38621.1 - 0.038 13.8 0.0 0.081 12.8 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Gp58 PF07902.11 CAM38621.1 - 0.064 11.5 0.7 0.11 10.8 0.7 1.3 1 0 0 1 1 1 0 gp58-like protein MAD PF05557.13 CAM38621.1 - 0.066 11.6 11.4 0.094 11.1 11.4 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein bZIP_1 PF00170.21 CAM38621.1 - 0.067 13.3 0.1 0.067 13.3 0.1 3.5 3 1 0 3 3 3 0 bZIP transcription factor PRKG1_interact PF15898.5 CAM38621.1 - 1.2 10.0 12.4 0.93 10.4 7.6 2.3 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Tho2 PF11262.8 CAM38621.1 - 1.3 8.2 2.9 1.8 7.7 2.9 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Spc7 PF08317.11 CAM38621.1 - 1.7 7.5 14.4 2.5 6.9 1.2 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein Golgin_A5 PF09787.9 CAM38621.1 - 2.3 7.6 10.4 3.5 7.0 10.4 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Epimerase PF01370.21 CAM38623.1 - 1.1e-16 61.0 0.0 2.1e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CAM38623.1 - 6.4e-08 32.7 0.0 1.3e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 CAM38623.1 - 6.9e-07 28.6 0.0 1.5e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 CAM38623.1 - 3.8e-06 26.7 0.0 0.00034 20.2 0.0 2.4 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 CAM38623.1 - 1.6e-05 24.5 0.2 3.2e-05 23.5 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase GCV_H PF01597.19 CAM38625.1 - 0.00021 21.1 0.1 0.00034 20.5 0.1 1.4 1 0 0 1 1 1 1 Glycine cleavage H-protein HA2 PF04408.23 CAM38627.1 - 3.4e-16 59.4 0.4 3.8e-15 56.1 0.0 2.8 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CAM38627.1 - 3.4e-12 46.7 0.2 1.1e-11 45.1 0.2 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CAM38627.1 - 2.1e-09 37.4 0.1 4.4e-09 36.3 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.26 CAM38627.1 - 3e-09 37.4 0.0 0.0017 19.0 0.0 4.3 4 0 0 4 4 4 2 Double-stranded RNA binding motif AAA_22 PF13401.6 CAM38627.1 - 0.00024 21.4 0.1 0.00076 19.8 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CAM38627.1 - 0.0017 18.7 0.1 0.0054 17.1 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 CAM38627.1 - 0.055 14.0 0.6 0.19 12.2 0.4 2.0 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 CAM38627.1 - 0.12 11.8 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.6 CAM38627.1 - 0.31 11.1 0.9 9.7 6.2 0.9 2.6 1 1 0 1 1 1 0 AAA domain TPP_enzyme_N PF02776.18 CAM38629.1 - 3.5e-32 111.4 0.3 1.1e-31 109.7 0.0 2.0 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 CAM38629.1 - 1.1e-21 77.3 0.0 1.9e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 CAM38629.1 - 4.7e-15 55.5 0.1 1.4e-14 54.0 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DXP_synthase_N PF13292.6 CAM38629.1 - 0.034 13.3 0.0 0.054 12.7 0.0 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase XFP_N PF09364.10 CAM38629.1 - 0.054 12.3 0.0 0.089 11.6 0.0 1.2 1 0 0 1 1 1 0 XFP N-terminal domain DRMBL PF07522.14 CAM38630.1 - 3.1e-18 65.9 0.0 5.7e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase DUF4379 PF14311.6 CAM38631.1 - 2e-14 53.7 0.1 3.7e-14 52.8 0.1 1.5 1 0 0 1 1 1 1 Probable Zinc-ribbon domain Prok-RING_4 PF14447.6 CAM38631.1 - 0.13 12.2 0.3 0.28 11.1 0.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-UBP PF02148.19 CAM38632.1 - 2.9e-17 62.7 5.7 9.8e-17 61.0 5.7 1.9 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Med4 PF10018.9 CAM38632.1 - 0.015 15.0 1.7 0.044 13.5 1.7 1.8 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 UPF0242 PF06785.11 CAM38632.1 - 0.043 13.9 3.8 0.12 12.4 3.8 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus NIF3 PF01784.18 CAM38632.1 - 0.076 12.6 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) DUF641 PF04859.12 CAM38632.1 - 0.19 12.1 4.2 0.095 13.0 1.4 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Amastin PF07344.11 CAM38633.1 - 8.7e-53 178.3 8.7 1e-52 178.1 8.7 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein SUR7 PF06687.12 CAM38633.1 - 0.96 9.0 18.8 3.8 7.1 0.6 3.1 2 1 0 3 3 3 0 SUR7/PalI family UPF0054 PF02130.17 CAM38635.1 - 5.8e-25 87.6 0.0 7.3e-25 87.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 LRR_6 PF13516.6 CAM38636.1 - 0.00025 20.9 7.4 0.085 13.0 0.9 4.4 4 0 0 4 4 4 2 Leucine Rich repeat LRR_8 PF13855.6 CAM38636.1 - 1.9 8.3 8.1 3 7.7 1.8 3.1 2 2 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.7 CAM38636.1 - 1.9 9.0 8.6 4.7 7.8 1.3 3.4 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) p450 PF00067.22 CAM38638.1 - 2.1e-60 204.8 0.0 3e-60 204.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1477 PF07346.11 CAM38638.1 - 0.0027 17.9 0.1 0.0056 16.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1477) AAA PF00004.29 CAM38640.1 - 1.7e-34 119.1 0.0 4.1e-34 117.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CAM38640.1 - 1.8e-05 25.2 0.2 6.9e-05 23.3 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CAM38640.1 - 0.00023 21.1 0.0 0.0014 18.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CAM38640.1 - 0.0004 20.7 0.1 0.094 13.0 0.2 3.0 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 CAM38640.1 - 0.0013 18.5 0.0 0.0038 17.0 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 CAM38640.1 - 0.0021 18.0 0.2 2.2 8.2 0.0 2.8 1 1 1 2 2 2 2 NACHT domain AAA_33 PF13671.6 CAM38640.1 - 0.0029 17.8 0.2 0.011 15.9 0.2 2.2 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CAM38640.1 - 0.004 16.9 0.0 0.027 14.2 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein TIP49 PF06068.13 CAM38640.1 - 0.0048 16.2 0.0 0.012 14.9 0.0 1.6 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_24 PF13479.6 CAM38640.1 - 0.0051 16.6 0.0 0.0086 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CAM38640.1 - 0.011 16.1 0.0 0.024 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Vps4_C PF09336.10 CAM38640.1 - 0.014 15.4 0.0 0.039 13.9 0.0 1.8 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain Hydin_ADK PF17213.3 CAM38640.1 - 0.056 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Mg_chelatase PF01078.21 CAM38640.1 - 0.074 12.4 0.0 0.26 10.6 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CAM38640.1 - 0.19 12.1 0.0 1.3 9.4 0.0 2.2 2 0 0 2 2 2 0 RNA helicase Tyr_Deacylase PF02580.16 CAM38641.1 - 1.7e-27 96.7 0.0 3.1e-27 95.9 0.0 1.4 1 1 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Aldose_epim PF01263.20 CAM38643.1 - 5.3e-32 111.3 0.0 7.2e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase HECT PF00632.25 CAM38644.1 - 9.5e-09 35.2 0.0 0.0014 18.2 0.0 2.1 2 0 0 2 2 2 2 HECT-domain (ubiquitin-transferase) HECT PF00632.25 CAM38645.1 - 9.5e-07 28.6 0.1 1.6e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Lactamase_B PF00753.27 CAM38646.2 - 3.5e-05 23.9 0.2 0.00013 22.0 0.2 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CAM38646.2 - 0.0081 15.7 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain HAGH_C PF16123.5 CAM38646.2 - 0.12 12.9 0.0 0.29 11.7 0.0 1.6 1 0 0 1 1 1 0 Hydroxyacylglutathione hydrolase C-terminus Beta-Casp PF10996.8 CAM38647.1 - 7.1e-32 110.0 0.0 2.9e-31 108.0 0.0 2.1 2 0 0 2 2 2 1 Beta-Casp domain CPSF73-100_C PF11718.8 CAM38647.1 - 3.3e-30 105.3 0.2 4.9e-30 104.7 0.2 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Lactamase_B PF00753.27 CAM38647.1 - 1.2e-22 80.9 0.1 2.1e-22 80.1 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 CAM38647.1 - 1.5e-16 60.4 0.0 4.9e-16 58.7 0.0 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 CAM38647.1 - 4.8e-13 48.8 0.1 1.7e-12 47.1 0.0 2.0 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 CAM38647.1 - 1.9e-10 40.6 0.3 1.7e-08 34.2 0.0 2.4 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CAM38647.1 - 0.00099 19.0 0.0 0.004 17.1 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Topoisom_I PF01028.20 CAM38648.1 - 4.9e-91 304.1 3.2 4.9e-91 304.1 3.2 1.8 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 CAM38648.1 - 9e-91 303.1 0.9 9e-91 303.1 0.9 3.5 2 1 1 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment DUF3891 PF13030.6 CAM38648.1 - 0.0088 15.8 2.3 0.18 11.6 0.7 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3891) LRR_9 PF14580.6 CAM38649.1 - 4.2e-07 29.6 0.1 9.3e-07 28.5 0.1 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CAM38649.1 - 0.015 15.7 0.0 0.015 15.7 0.0 2.7 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) TMF_TATA_bd PF12325.8 CAM38649.1 - 0.07 13.3 0.1 0.3 11.3 0.0 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding zf-RanBP PF00641.18 CAM38650.1 - 2.5e-05 23.5 2.6 2.5e-05 23.5 2.6 1.8 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others zf-CCCH_4 PF18044.1 CAM38650.1 - 7.9e-05 22.4 1.2 7.9e-05 22.4 1.2 3.0 3 0 0 3 3 3 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CAM38650.1 - 0.00089 19.2 1.5 0.0026 17.7 1.5 1.9 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 CAM38650.1 - 0.043 13.7 1.6 0.13 12.2 1.6 1.8 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Amidinotransf PF02274.17 CAM38651.1 - 7e-11 41.8 0.0 9.1e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 Amidinotransferase Caroten_synth PF04240.12 CAM38651.1 - 0.21 11.4 0.0 0.33 10.8 0.0 1.2 1 0 0 1 1 1 0 Carotenoid biosynthesis protein LRR_6 PF13516.6 CAM38652.2 - 0.14 12.3 0.5 0.99 9.6 0.0 2.6 2 0 0 2 2 2 0 Leucine Rich repeat TPR_12 PF13424.6 CAM38653.1 - 5.7e-33 113.1 18.2 2.6e-08 34.0 4.2 7.1 2 1 5 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.6 CAM38653.1 - 4.6e-24 83.5 24.0 4.7e-08 32.6 0.0 7.9 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 CAM38653.1 - 1.9e-09 37.0 18.8 0.027 14.7 0.1 7.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 CAM38653.1 - 0.0029 17.5 16.4 2.2 8.5 0.5 6.7 6 0 0 6 6 6 1 Tetratricopeptide repeat Drf_FH3 PF06367.16 CAM38653.1 - 0.0072 16.0 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Diaphanous FH3 Domain DUF2225 PF09986.9 CAM38653.1 - 0.0084 15.9 0.3 2.3 7.9 0.0 3.2 2 1 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_17 PF13431.6 CAM38653.1 - 0.02 15.2 6.8 37 5.0 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat DHR-2 PF06920.13 CAM38653.1 - 0.086 11.5 0.0 0.14 10.7 0.0 1.3 1 0 0 1 1 1 0 Dock homology region 2 TPR_4 PF07721.14 CAM38653.1 - 0.14 12.9 0.5 0.14 12.9 0.5 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 CAM38653.1 - 0.31 12.0 15.8 7.8 7.6 0.1 5.8 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 CAM38653.1 - 0.58 10.1 18.8 7.9 6.5 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 CAM38653.1 - 0.81 10.5 16.8 2.4 9.0 1.1 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 CAM38653.1 - 1.4 9.7 22.4 7.9 7.2 1.3 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 CAM38653.1 - 1.4 9.3 23.7 1.6 9.0 0.5 6.7 8 0 0 8 8 8 0 Tetratricopeptide repeat DUF1771 PF08590.10 CAM38653.1 - 4.1 7.8 12.0 6.9 7.1 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF1771) TIP49 PF06068.13 CAM38654.1 - 1.4e-166 554.0 0.6 1.8e-166 553.7 0.6 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CAM38654.1 - 2.4e-19 69.2 0.4 9.1e-19 67.4 0.1 2.2 2 0 0 2 2 1 1 TIP49 AAA-lid domain AAA PF00004.29 CAM38654.1 - 9.8e-12 45.4 0.8 3.7e-07 30.6 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CAM38654.1 - 2.3e-11 43.7 0.0 1.4e-07 31.4 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CAM38654.1 - 7.4e-07 29.5 0.1 0.01 16.1 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CAM38654.1 - 2e-05 25.0 0.4 0.00042 20.7 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 CAM38654.1 - 0.00016 21.2 0.2 0.0091 15.4 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CAM38654.1 - 0.00028 20.9 0.1 0.11 12.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 CAM38654.1 - 0.007 16.7 3.4 2.8 8.3 0.1 3.0 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 CAM38654.1 - 0.0072 16.5 0.0 0.024 14.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.15 CAM38654.1 - 0.0077 15.6 0.0 0.024 14.0 0.0 1.8 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_28 PF13521.6 CAM38654.1 - 0.014 15.6 0.0 0.036 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CAM38654.1 - 0.015 14.9 0.0 0.027 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CAM38654.1 - 0.019 14.8 0.0 0.074 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 CAM38654.1 - 0.026 14.5 0.1 1.9 8.5 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 CAM38654.1 - 0.039 14.5 0.1 0.18 12.4 0.0 2.2 3 0 0 3 3 2 0 AAA domain AAA_7 PF12775.7 CAM38654.1 - 0.052 13.1 0.2 0.31 10.5 0.0 2.1 2 1 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 CAM38654.1 - 0.063 13.0 0.0 0.19 11.4 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein Rad17 PF03215.15 CAM38654.1 - 0.069 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain TsaE PF02367.17 CAM38654.1 - 0.074 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 CAM38654.1 - 0.076 13.4 1.2 1.4 9.4 0.1 3.1 1 1 2 3 3 3 0 AAA domain Sigma54_activat PF00158.26 CAM38654.1 - 0.089 12.5 0.1 10 5.8 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain SET PF00856.28 CAM38655.1 - 0.0022 18.4 0.0 0.0034 17.8 0.0 1.3 1 1 0 1 1 1 1 SET domain AAA PF00004.29 CAM38656.1 - 1e-46 158.7 0.0 2.3e-37 128.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 CAM38656.1 - 9.4e-16 58.0 0.2 4e-15 56.0 0.2 2.2 2 0 0 2 2 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.6 CAM38656.1 - 1.4e-12 48.3 0.5 0.00088 19.7 0.1 4.0 2 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 CAM38656.1 - 5.9e-09 36.3 0.2 0.0045 17.3 0.0 3.1 2 1 1 3 3 3 2 AAA domain AAA_33 PF13671.6 CAM38656.1 - 5.9e-07 29.8 0.0 0.0056 16.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 CAM38656.1 - 2e-06 27.5 0.0 0.076 12.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 CAM38656.1 - 3.6e-05 23.8 0.0 0.002 18.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 CAM38656.1 - 4.2e-05 22.8 0.0 0.013 14.7 0.0 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF815) ATP-synt_ab PF00006.25 CAM38656.1 - 5.8e-05 22.8 0.2 0.095 12.3 0.0 3.0 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain T2SSE PF00437.20 CAM38656.1 - 0.00021 20.4 0.0 0.3 10.1 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein RNA_helicase PF00910.22 CAM38656.1 - 0.00024 21.5 0.0 0.09 13.2 0.0 3.1 3 0 0 3 3 2 1 RNA helicase ABC_tran PF00005.27 CAM38656.1 - 0.00025 21.6 0.0 0.29 11.6 0.0 2.8 3 0 0 3 3 2 1 ABC transporter AAA_29 PF13555.6 CAM38656.1 - 0.00027 20.6 0.0 0.66 9.8 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 CAM38656.1 - 0.00033 20.3 3.1 1.6 8.2 0.0 4.9 4 1 0 5 5 5 1 AAA domain AAA_2 PF07724.14 CAM38656.1 - 0.00037 20.6 0.0 0.0012 19.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CAM38656.1 - 0.00044 20.3 0.0 0.14 12.2 0.0 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 CAM38656.1 - 0.00061 20.1 0.0 0.19 12.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 CAM38656.1 - 0.00067 19.6 0.0 0.26 11.2 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain Vps4_C PF09336.10 CAM38656.1 - 0.001 19.0 0.0 0.0028 17.6 0.0 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_28 PF13521.6 CAM38656.1 - 0.0011 19.2 0.0 0.31 11.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 CAM38656.1 - 0.0012 18.8 0.1 0.092 12.6 0.0 2.9 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 CAM38656.1 - 0.0025 17.6 0.1 1.6 8.4 0.0 2.7 3 0 0 3 3 2 1 IstB-like ATP binding protein Sigma54_activat PF00158.26 CAM38656.1 - 0.0036 17.0 0.1 2.1 8.0 0.0 2.9 3 0 0 3 3 3 1 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.18 CAM38656.1 - 0.0044 16.4 0.1 0.027 13.8 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family NACHT PF05729.12 CAM38656.1 - 0.0049 16.8 0.5 3.6 7.5 0.0 3.8 4 1 1 5 5 3 1 NACHT domain RsgA_GTPase PF03193.16 CAM38656.1 - 0.0087 16.0 0.1 4.1 7.3 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 CAM38656.1 - 0.01 15.6 0.2 1.4 8.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_lid_3 PF17862.1 CAM38656.1 - 0.011 15.5 0.0 0.045 13.6 0.0 2.1 1 0 0 1 1 1 0 AAA+ lid domain Mg_chelatase PF01078.21 CAM38656.1 - 0.015 14.7 0.0 5.8 6.2 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 CAM38656.1 - 0.021 15.3 0.0 3.3 8.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain YAcAr PF10686.9 CAM38656.1 - 0.032 14.2 0.0 0.17 11.9 0.0 2.3 2 0 0 2 2 1 0 YspA, cpYpsA-related SLOG family AAA_18 PF13238.6 CAM38656.1 - 0.037 14.6 0.0 1.5 9.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 CAM38656.1 - 0.051 13.0 0.0 3 7.2 0.0 2.5 2 0 0 2 2 2 0 Bacterial TniB protein TsaE PF02367.17 CAM38656.1 - 0.069 13.2 0.0 6.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TrwB_AAD_bind PF10412.9 CAM38656.1 - 0.13 11.2 0.0 4.1 6.2 0.0 2.6 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.12 CAM38656.1 - 0.15 11.4 0.0 20 4.4 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Septin PF00735.18 CAM38656.1 - 0.25 10.6 0.1 6.7 5.9 0.0 2.2 2 0 0 2 2 2 0 Septin DUF3140 PF11338.8 CAM38657.1 - 0.14 12.6 0.0 0.5 10.8 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) LicD PF04991.13 CAM38658.1 - 5.3e-08 33.3 0.0 0.0022 18.2 0.1 2.1 2 0 0 2 2 2 2 LicD family Deltaretro_Tax PF05599.11 CAM38658.1 - 0.0058 17.1 0.0 0.025 15.1 0.0 2.0 2 0 0 2 2 2 1 Deltaretrovirus Tax protein PDCD2_C PF04194.13 CAM38659.1 - 3.1e-22 79.5 0.1 3.1e-22 79.5 0.1 2.3 3 0 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain Elf1 PF05129.13 CAM38659.1 - 0.043 13.9 0.7 0.19 11.8 0.2 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.10 CAM38659.1 - 0.25 11.5 2.5 20 5.4 0.2 3.4 3 0 0 3 3 3 0 Zinc ribbon domain CpXC PF14353.6 CAM38659.1 - 0.51 10.4 3.7 12 6.0 0.0 2.9 2 1 0 2 2 2 0 CpXC protein DUF2752 PF10825.8 CAM38659.1 - 0.58 10.3 3.3 0.67 10.1 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2752) zf-RRN7 PF11781.8 CAM38659.1 - 0.63 9.8 6.3 1.2 8.9 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Ank_2 PF12796.7 CAM38660.1 - 1.4e-29 102.5 2.3 1.2e-13 51.4 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CAM38660.1 - 1.2e-21 76.8 0.3 0.00018 22.0 0.1 5.4 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 CAM38660.1 - 9.3e-21 73.3 2.1 4.2e-05 23.8 0.2 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 CAM38660.1 - 9.5e-18 62.5 0.3 0.00035 20.8 0.1 5.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 CAM38660.1 - 7.8e-16 57.9 4.8 5.2e-05 23.5 0.4 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) DUF3372 PF11852.8 CAM38660.1 - 0.052 13.0 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) Integrin_beta PF00362.18 CAM38662.1 - 0.022 14.4 0.0 9.4 5.8 0.0 2.5 2 1 0 2 2 2 0 Integrin beta chain VWA domain PI3_PI4_kinase PF00454.27 CAM38663.1 - 3e-35 122.2 0.0 7.1e-24 85.0 0.0 2.3 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 CAM38663.1 - 0.0044 16.4 0.0 0.0075 15.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) PfkB PF00294.24 CAM38664.1 - 1.5e-44 152.5 0.1 2.1e-43 148.8 0.1 2.0 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Complex1_LYR PF05347.15 CAM38665.1 - 4.5e-09 36.2 0.9 6.9e-09 35.6 0.9 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF3336 PF11815.8 CAM38666.1 - 8.1e-20 71.0 0.0 1.4e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 CAM38666.1 - 5.4e-08 33.3 5.2 2.1e-07 31.4 5.1 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase Ribosomal_L25p PF01386.19 CAM38666.1 - 0.087 13.4 0.0 2.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Ribosomal L25p family Metallophos PF00149.28 CAM38667.1 - 3.1e-07 31.1 0.0 5.4e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ChAPs PF09295.10 CAM38667.1 - 0.15 11.1 0.0 0.22 10.5 0.0 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) FixS PF03597.15 CAM38667.1 - 1.1 9.1 3.5 3.2 7.5 3.5 1.8 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type DUF4131 PF13567.6 CAM38667.1 - 4.2 7.0 6.5 0.14 11.8 0.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) zf-U1 PF06220.12 CAM38668.1 - 0.12 12.2 0.3 0.25 11.2 0.3 1.5 1 0 0 1 1 1 0 U1 zinc finger MHYT PF03707.16 CAM38668.1 - 3.1 8.0 9.4 0.8 9.9 0.7 2.5 2 1 0 2 2 2 0 Bacterial signalling protein N terminal repeat MIG-14_Wnt-bd PF06664.12 CAM38669.1 - 0.11 11.7 0.1 0.14 11.4 0.1 1.1 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion Ribosomal_L21e PF01157.18 CAM38670.1 - 1.5e-40 137.2 3.1 2.1e-40 136.7 3.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e EMP70 PF02990.16 CAM38671.1 - 7.1e-133 444.0 5.4 9e-133 443.7 5.4 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 ATP-synt_ab PF00006.25 CAM38672.1 - 2.1e-105 351.1 0.0 3.5e-105 350.3 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 CAM38672.1 - 4.5e-45 152.4 0.5 9.8e-45 151.3 0.1 1.8 2 0 0 2 2 2 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 CAM38672.1 - 3.1e-14 53.2 1.8 3.1e-14 53.2 1.8 2.7 3 0 0 3 3 3 1 ATP synthase alpha/beta family, beta-barrel domain DUF2737 PF10930.8 CAM38672.1 - 0.019 14.6 0.2 5.9 6.5 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2737) Ribosomal_L13 PF00572.18 CAM38673.1 - 1.2e-28 99.9 0.1 1.5e-28 99.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Ins_P5_2-kin PF06090.12 CAM38675.1 - 2.2e-25 89.8 0.0 3e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase GHBP PF12772.7 CAM38675.1 - 0.098 12.2 0.2 0.24 10.9 0.2 1.6 1 0 0 1 1 1 0 Growth hormone receptor binding ART-PolyVal PF18760.1 CAM38676.1 - 0.011 16.7 1.1 0.019 16.0 1.1 1.5 1 1 0 1 1 1 0 ADP-Ribosyltransferase in polyvalent proteins DUF501 PF04417.12 CAM38677.1 - 7.5e-28 97.1 0.3 1.5e-27 96.1 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF501) Aminotran_1_2 PF00155.21 CAM38679.2 - 3.1e-45 154.9 0.0 3.7e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CAM38679.2 - 0.003 16.9 0.0 0.0045 16.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase KH_5 PF13184.6 CAM38679.2 - 0.76 9.9 3.1 11 6.1 0.1 2.6 3 0 0 3 3 3 0 NusA-like KH domain LIM PF00412.22 CAM38681.2 - 0.011 16.0 7.1 0.033 14.4 7.1 1.8 1 0 0 1 1 1 0 LIM domain zf-HYPF PF07503.12 CAM38681.2 - 0.022 14.5 3.7 0.022 14.5 3.7 3.0 3 0 0 3 3 3 0 HypF finger Lar_restr_allev PF14354.6 CAM38681.2 - 5 7.6 8.8 3.7 8.0 0.1 2.8 1 1 1 2 2 2 0 Restriction alleviation protein Lar Actin PF00022.19 CAM38682.1 - 1.3e-37 129.4 0.0 1.9e-33 115.7 0.0 3.0 2 1 0 2 2 2 2 Actin FtsA PF14450.6 CAM38682.1 - 0.0031 17.9 0.0 0.0045 17.4 0.0 1.4 1 0 0 1 1 1 1 Cell division protein FtsA PGM_PMM_I PF02878.16 CAM38684.1 - 2.1e-36 124.7 0.0 4.5e-36 123.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 CAM38684.1 - 5.7e-21 75.1 0.0 1.5e-20 73.7 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 CAM38684.1 - 1.8e-14 53.9 0.1 1.7e-13 50.8 0.1 2.4 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 CAM38684.1 - 0.00018 21.6 0.0 0.00056 20.0 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Hira PF07569.11 CAM38685.2 - 0.052 13.3 0.7 14 5.3 0.0 3.8 3 1 1 4 4 4 0 TUP1-like enhancer of split ANAPC4_WD40 PF12894.7 CAM38685.2 - 0.091 13.1 0.1 32 4.9 0.0 4.0 4 1 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 CAM38685.2 - 0.094 11.6 0.7 0.22 10.4 0.7 1.6 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain APO_RNA-bind PF05634.11 CAM38687.2 - 0.089 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 APO RNA-binding Ribosomal_L14 PF00238.19 CAM38688.1 - 2.1e-21 76.2 0.1 3.5e-21 75.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e TPR_1 PF00515.28 CAM38689.1 - 2.2e-07 30.4 7.9 0.051 13.4 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CAM38689.1 - 5.1e-06 26.2 10.3 0.094 12.9 0.2 4.0 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 CAM38689.1 - 0.00013 21.6 0.1 0.018 14.7 0.0 2.9 3 0 0 3 3 3 1 TPR repeat TPR_19 PF14559.6 CAM38689.1 - 0.0016 18.9 0.1 0.15 12.6 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CAM38689.1 - 0.0078 16.5 4.4 14 6.0 0.0 3.9 2 1 2 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CAM38689.1 - 0.0094 16.2 5.3 0.73 10.1 1.5 3.5 2 1 2 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 CAM38689.1 - 0.04 14.3 0.7 0.97 9.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial transcriptional activator domain TPR_16 PF13432.6 CAM38689.1 - 0.13 12.9 4.8 12 6.6 0.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CAM38689.1 - 0.14 13.0 2.2 31 5.8 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CAM38689.1 - 0.3 11.8 2.5 17 6.3 0.4 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 CAM38689.1 - 0.56 10.6 6.8 17 5.9 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Spc7 PF08317.11 CAM38690.1 - 1.6e-05 24.0 2.4 1.6e-05 24.0 2.4 1.6 2 0 0 2 2 2 1 Spc7 kinetochore protein DUF745 PF05335.13 CAM38690.1 - 3.7e-05 23.5 15.1 0.0039 16.9 8.3 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF745) ATG16 PF08614.11 CAM38690.1 - 0.008 16.4 15.3 1.2 9.3 13.2 2.5 2 1 0 2 2 2 2 Autophagy protein 16 (ATG16) THOC7 PF05615.13 CAM38690.1 - 0.013 15.8 3.6 0.013 15.8 3.6 2.2 2 0 0 2 2 2 0 Tho complex subunit 7 TMCO5 PF14992.6 CAM38690.1 - 0.02 14.5 2.9 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 TMCO5 family Atg14 PF10186.9 CAM38690.1 - 0.029 13.5 4.6 0.032 13.3 4.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 KIAA1430 PF13879.6 CAM38690.1 - 0.047 14.5 2.5 0.84 10.4 0.0 2.5 2 0 0 2 2 2 0 KIAA1430 homologue LMBR1 PF04791.16 CAM38690.1 - 0.075 11.9 0.5 0.087 11.7 0.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein MT PF12777.7 CAM38690.1 - 0.082 11.9 0.5 0.11 11.5 0.5 1.2 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor DUF4201 PF13870.6 CAM38690.1 - 0.1 12.3 7.6 0.025 14.3 4.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) CENP-H PF05837.12 CAM38690.1 - 0.25 11.8 14.6 1.1 9.7 0.1 2.5 2 1 0 2 2 2 0 Centromere protein H (CENP-H) GAS PF13851.6 CAM38690.1 - 0.25 10.7 8.9 0.34 10.2 5.5 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Nup88 PF10168.9 CAM38690.1 - 0.3 8.9 3.9 0.37 8.6 3.9 1.1 1 0 0 1 1 1 0 Nuclear pore component DUF2951 PF11166.8 CAM38690.1 - 0.31 11.3 3.5 7 6.9 1.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2951) Spc24 PF08286.11 CAM38690.1 - 0.44 10.8 7.9 0.85 9.9 3.9 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 ADIP PF11559.8 CAM38690.1 - 0.48 10.5 11.8 0.64 10.1 7.5 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.8 CAM38690.1 - 0.66 10.0 7.6 4.2 7.4 0.0 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CALCOCO1 PF07888.11 CAM38690.1 - 0.66 8.8 15.8 0.017 14.0 8.3 1.8 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like PRKG1_interact PF15898.5 CAM38690.1 - 1.6 9.7 13.4 10 7.1 7.8 2.7 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Exonuc_VII_L PF02601.15 CAM38690.1 - 1.6 8.2 11.5 2.5 7.6 11.5 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit COG2 PF06148.11 CAM38690.1 - 1.7 8.7 6.1 0.82 9.8 3.2 2.0 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3287 PF11690.8 CAM38690.1 - 6.3 6.5 7.9 0.3 10.8 0.3 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3287) MIP PF00230.20 CAM38692.1 - 1.5e-33 116.4 19.9 8.4e-33 114.0 19.9 1.8 1 1 0 1 1 1 1 Major intrinsic protein LSM PF01423.22 CAM38693.1 - 7.5e-12 44.8 0.4 9.3e-12 44.5 0.4 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CAM38693.1 - 0.00014 22.0 0.1 0.00021 21.4 0.1 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 CAM38693.1 - 0.14 12.3 0.1 0.2 11.8 0.1 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain DnaJ PF00226.31 CAM38694.1 - 9.5e-18 64.1 0.0 2e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Fer4_20 PF14691.6 CAM38694.1 - 0.15 11.8 1.1 0.39 10.5 0.4 2.0 2 0 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster AAA_6 PF12774.7 CAM38695.1 - 3.1e-153 509.5 0.0 3.6e-152 506.0 0.0 2.9 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 CAM38695.1 - 7.5e-139 463.9 1.4 7.5e-139 463.9 1.4 3.0 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 CAM38695.1 - 1.6e-112 376.6 6.5 1.6e-112 376.6 6.5 5.3 7 0 0 7 7 6 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 CAM38695.1 - 1.6e-100 335.7 0.0 3.8e-100 334.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CAM38695.1 - 1.1e-81 274.4 0.3 3.4e-81 272.8 0.3 1.9 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 CAM38695.1 - 8.2e-74 247.4 0.0 8.2e-74 247.4 0.0 3.7 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 CAM38695.1 - 3.2e-64 215.8 8.2 8.1e-47 159.1 0.0 4.8 5 0 0 5 5 5 3 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CAM38695.1 - 2e-49 167.6 0.0 5.9e-49 166.0 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CAM38695.1 - 1.7e-43 147.5 0.1 4.9e-42 142.8 0.1 3.1 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 CAM38695.1 - 1.5e-41 142.6 9.1 2.6e-41 141.8 9.1 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 CAM38695.1 - 1.3e-21 77.0 0.1 8.1e-21 74.4 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CAM38695.1 - 4.5e-21 75.3 4.1 1.9e-07 31.1 0.0 7.2 6 2 0 6 6 5 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 CAM38695.1 - 1.5e-14 54.0 0.0 7.3e-14 51.8 0.0 2.2 2 0 0 2 2 1 1 AAA+ lid domain AAA PF00004.29 CAM38695.1 - 4.9e-08 33.5 5.5 0.69 10.3 0.0 6.6 7 0 0 7 7 5 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CAM38695.1 - 1.1e-06 29.2 8.7 0.14 12.6 0.0 7.1 6 1 0 6 6 5 1 AAA ATPase domain AAA_33 PF13671.6 CAM38695.1 - 4.9e-05 23.5 7.9 0.038 14.2 0.0 5.3 5 0 0 5 5 4 2 AAA domain RsgA_GTPase PF03193.16 CAM38695.1 - 0.00026 20.9 1.5 0.036 14.0 0.2 3.7 3 0 0 3 3 3 1 RsgA GTPase COG5 PF10392.9 CAM38695.1 - 0.0017 18.5 1.9 0.098 12.8 0.8 3.7 2 0 0 2 2 2 1 Golgi transport complex subunit 5 AAA_18 PF13238.6 CAM38695.1 - 0.0089 16.6 4.0 5 7.7 0.0 4.9 5 0 0 5 5 4 1 AAA domain Rad17 PF03215.15 CAM38695.1 - 0.011 15.7 1.4 1.5 8.7 0.1 3.6 4 0 0 4 4 3 0 Rad17 P-loop domain AAA_22 PF13401.6 CAM38695.1 - 0.024 14.9 10.7 2 8.7 0.0 6.0 7 0 0 7 7 4 0 AAA domain DUF406 PF04175.12 CAM38695.1 - 0.054 14.0 3.4 0.13 12.8 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF406) AAA_29 PF13555.6 CAM38695.1 - 0.055 13.2 0.4 1.6 8.6 0.1 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 CAM38695.1 - 0.072 13.5 2.3 4.1 7.8 0.0 3.3 3 0 0 3 3 3 0 RNA helicase AAA_30 PF13604.6 CAM38695.1 - 0.085 12.6 5.5 5.1 6.8 0.1 3.7 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.27 CAM38695.1 - 0.088 13.3 7.5 1.2 9.6 0.1 4.4 5 0 0 5 5 3 0 ABC transporter DUF1612 PF07756.12 CAM38695.1 - 0.85 9.9 5.6 4.3 7.6 5.6 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1612) HATPase_c PF02518.26 CAM38697.1 - 1.5e-10 41.6 0.0 3e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NMO PF03060.15 CAM38697.1 - 0.046 13.1 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase FAM222A PF15258.6 CAM38697.1 - 0.25 10.4 0.5 0.51 9.4 0.5 1.4 1 0 0 1 1 1 0 Protein family of FAM222A Pet191_N PF10203.9 CAM38698.1 - 2.9e-09 37.1 3.1 4.2e-09 36.6 3.1 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 CAM38698.1 - 0.49 10.4 4.8 2.3 8.3 0.3 2.6 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, NIF PF03031.18 CAM38699.2 - 3.7e-27 95.0 0.0 5.6e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF705 PF05152.12 CAM38699.2 - 3.4e-05 23.5 0.0 5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF705) SWI-SNF_Ssr4 PF08549.10 CAM38699.2 - 0.047 12.3 0.7 0.059 12.0 0.7 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) PI3_PI4_kinase PF00454.27 CAM38701.1 - 1e-56 192.6 0.1 2.7e-56 191.2 0.1 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 CAM38701.1 - 6.2e-24 84.8 0.1 1.3e-23 83.8 0.1 1.6 1 0 0 1 1 1 1 FAT domain FRB_dom PF08771.11 CAM38701.1 - 2.3e-13 50.4 2.9 4.6e-13 49.4 0.5 3.0 3 0 0 3 3 3 1 FKBP12-rapamycin binding domain DUF3385 PF11865.8 CAM38701.1 - 3.5e-13 49.8 4.1 2e-12 47.3 0.4 3.3 2 1 0 2 2 2 1 Domain of unknown function (DUF3385) FATC PF02260.20 CAM38701.1 - 4e-11 42.5 0.4 1.2e-10 41.1 0.0 2.1 2 0 0 2 2 2 1 FATC domain PDZ_6 PF17820.1 CAM38701.1 - 4.5e-06 26.4 0.1 1.8e-05 24.5 0.1 2.1 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CAM38701.1 - 0.001 19.3 0.1 0.0025 18.1 0.1 1.5 1 0 0 1 1 1 1 PDZ domain IFRD PF05004.13 CAM38701.1 - 0.0059 15.8 1.4 0.23 10.5 0.2 3.1 2 0 0 2 2 2 1 Interferon-related developmental regulator (IFRD) PDZ_2 PF13180.6 CAM38701.1 - 0.054 13.8 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 PDZ domain HEAT_2 PF13646.6 CAM38701.1 - 0.12 12.8 13.4 1.1 9.6 0.4 6.0 5 1 1 6 6 5 0 HEAT repeats TPR_11 PF13414.6 CAM38701.1 - 0.17 11.6 0.0 0.46 10.2 0.0 1.7 1 0 0 1 1 1 0 TPR repeat Nsp1_C PF05064.13 CAM38702.1 - 0.07 12.9 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Nsp1-like C-terminal region SHIPPO-rpt PF07004.12 CAM38702.1 - 0.18 12.8 1.3 0.54 11.3 1.3 1.9 1 0 0 1 1 1 0 Sperm-tail PG-rich repeat Tmemb_cc2 PF10267.9 CAM38702.1 - 1.4 8.0 3.3 1.1 8.4 1.2 1.5 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein PIG-Y PF15159.6 CAM38703.1 - 5.5e-07 30.4 1.6 7.5e-07 30.0 1.6 1.2 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y HECT PF00632.25 CAM38705.1 - 1.6e-44 152.7 0.0 4.3e-44 151.2 0.0 1.7 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) C1_2 PF03107.16 CAM38705.1 - 1.7 9.1 14.8 5.4 7.4 14.8 2.0 1 0 0 1 1 1 0 C1 domain Adaptin_N PF01602.20 CAM38706.1 - 5.1e-73 246.4 4.7 6.8e-73 246.0 4.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 CAM38706.1 - 4.4e-09 36.6 0.1 1e-08 35.5 0.1 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain CLASP_N PF12348.8 CAM38706.1 - 0.44 10.1 2.8 17 4.9 0.0 3.6 3 1 0 3 3 3 0 CLASP N terminal PMEI PF04043.15 CAM38706.1 - 4.5 7.6 6.9 1.5 9.1 0.3 3.0 2 1 0 3 3 3 0 Plant invertase/pectin methylesterase inhibitor Ribosomal_L7Ae PF01248.26 CAM38707.1 - 5.8e-19 67.6 0.5 7.6e-19 67.2 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Rgp1 PF08737.10 CAM38708.1 - 1.9e-08 33.9 0.0 3.3e-05 23.3 0.0 2.1 2 0 0 2 2 2 2 Rgp1 Peptidase_C78 PF07910.13 CAM38709.2 - 1.2e-48 165.4 0.0 1.6e-48 165.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.19 CAM38709.2 - 0.12 11.7 0.1 0.47 9.8 0.0 1.9 2 0 0 2 2 2 0 Peptidase family C54 DUF445 PF04286.12 CAM38711.1 - 0.018 14.9 0.2 0.023 14.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) FANCI_S1-cap PF14674.6 CAM38711.1 - 0.098 12.8 0.4 3.8 7.7 0.0 2.5 2 0 0 2 2 2 0 FANCI solenoid 1 cap UNC45-central PF11701.8 CAM38711.1 - 0.16 11.9 1.5 0.5 10.3 1.5 1.9 1 1 0 1 1 1 0 Myosin-binding striated muscle assembly central Prenyltrans PF00432.21 CAM38712.1 - 3.1e-71 234.7 13.4 1.8e-14 53.2 0.3 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 CAM38712.1 - 5.6e-09 35.5 0.0 0.011 14.8 0.0 4.1 1 1 3 4 4 4 3 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 CAM38712.1 - 4.6e-05 22.7 0.7 0.0094 15.1 0.0 3.2 1 1 3 4 4 4 2 Squalene-hopene cyclase C-terminal domain TED_complement PF07678.14 CAM38712.1 - 0.22 10.5 0.1 3.3 6.6 0.0 2.9 3 2 1 4 4 4 0 A-macroglobulin TED domain Phage_tail_L PF05100.12 CAM38714.1 - 0.16 11.2 0.1 0.37 10.1 0.0 1.6 2 0 0 2 2 2 0 Phage minor tail protein L UCH PF00443.29 CAM38715.2 - 4.5e-37 127.9 0.3 7.7e-37 127.2 0.1 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CAM38715.2 - 1.6e-13 51.0 0.0 5.3e-13 49.3 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 CAM38715.2 - 0.055 12.9 0.3 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Casc1_N PF15927.5 CAM38716.1 - 4.3e-10 39.6 5.1 4.5e-09 36.3 5.1 2.2 1 1 0 1 1 1 1 Cancer susceptibility candidate 1 N-terminus SLT_L PF14718.6 CAM38716.1 - 0.14 12.4 1.8 0.45 10.7 1.8 1.9 1 0 0 1 1 1 0 Soluble lytic murein transglycosylase L domain DnaJ PF00226.31 CAM38717.1 - 8.2e-07 29.1 0.2 4.3e-06 26.8 0.0 2.2 3 0 0 3 3 3 1 DnaJ domain GRIP PF01465.20 CAM38718.1 - 1e-11 44.5 0.7 1.2e-10 41.1 0.1 2.6 2 0 0 2 2 2 1 GRIP domain SesA PF17107.5 CAM38718.1 - 0.18 12.0 5.1 0.66 10.2 2.8 2.7 2 1 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Acetyltransf_11 PF13720.6 CAM38718.1 - 0.27 11.7 1.5 37 4.9 0.0 3.4 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Lipoprotein_6 PF01441.19 CAM38718.1 - 0.35 10.8 3.2 2.8 7.9 0.5 2.6 2 1 0 2 2 2 0 Lipoprotein MPS2 PF17060.5 CAM38718.1 - 0.53 9.5 8.3 0.56 9.4 5.7 2.1 2 0 0 2 2 2 0 Monopolar spindle protein 2 Baculo_PEP_C PF04513.12 CAM38718.1 - 1.6 8.8 12.1 0.53 10.3 5.9 2.8 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus HIP1_clath_bdg PF16515.5 CAM38718.1 - 1.8 9.2 39.5 0.12 13.0 7.4 4.7 4 1 1 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Prominin PF05478.11 CAM38718.1 - 3.2 5.6 14.2 0.36 8.7 9.7 1.5 2 0 0 2 2 2 0 Prominin DUF16 PF01519.16 CAM38718.1 - 4.9 7.7 12.8 0.089 13.3 3.2 2.8 3 0 0 3 3 3 0 Protein of unknown function DUF16 FliD_N PF02465.18 CAM38718.1 - 6.1 7.6 15.0 10 6.9 0.4 3.2 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Cauli_AT PF03233.13 CAM38718.1 - 6.8 6.6 8.2 11 5.9 4.4 2.8 2 1 1 3 3 3 0 Aphid transmission protein DUF1664 PF07889.12 CAM38718.1 - 9.1 6.3 14.3 1.6 8.8 5.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Peptidase_C50 PF03568.17 CAM38720.2 - 0.022 13.9 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C50 Abhydrolase_1 PF00561.20 CAM38721.1 - 5e-05 23.1 0.0 0.0001 22.1 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CAM38721.1 - 5.3e-05 22.6 0.0 8.1e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CAM38721.1 - 0.00068 20.3 0.1 0.00086 20.0 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF4892 PF16234.5 CAM38721.1 - 0.019 14.5 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4892) EMC1_C PF07774.13 CAM38722.1 - 1.4e-47 162.2 0.0 5.4e-47 160.2 0.0 1.9 2 0 0 2 2 2 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 CAM38722.1 - 0.018 14.6 1.9 0.75 9.3 0.6 3.5 4 1 1 5 5 5 0 PQQ-like domain PQQ_3 PF13570.6 CAM38722.1 - 1.5 9.4 3.5 4 8.1 0.1 3.6 3 0 0 3 3 3 0 PQQ-like domain REPA_OB_2 PF16900.5 CAM38724.2 - 0.00051 19.9 0.2 0.0012 18.7 0.2 1.6 1 1 0 1 1 1 1 Replication protein A OB domain OS-D PF03392.13 CAM38724.2 - 0.044 13.9 0.1 0.16 12.1 0.0 1.9 1 1 1 2 2 2 0 Insect pheromone-binding family, A10/OS-D AAA_6 PF12774.7 CAM38725.1 - 8.7e-127 422.6 0.0 3.5e-126 420.6 0.0 2.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CAM38725.1 - 1.8e-107 359.9 4.5 1.8e-107 359.9 4.5 5.1 4 1 1 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 CAM38725.1 - 2.8e-64 216.3 0.6 2.8e-64 216.3 0.6 3.2 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 CAM38725.1 - 3.6e-46 157.6 0.9 8.1e-44 149.9 0.0 3.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 DHC_N1 PF08385.12 CAM38725.1 - 3.7e-36 124.9 0.0 3.7e-36 124.9 0.0 3.7 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_5 PF07728.14 CAM38725.1 - 5.2e-32 110.7 0.0 6.5e-21 74.8 0.0 5.5 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CAM38725.1 - 1.7e-29 102.6 0.2 3.1e-24 85.5 0.0 3.7 3 0 0 3 3 3 2 P-loop containing dynein motor region Dynein_heavy PF03028.15 CAM38725.1 - 2.7e-29 101.7 0.0 2.1e-28 98.8 0.0 2.8 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 CAM38725.1 - 9e-29 100.4 0.0 1.8e-28 99.4 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 CAM38725.1 - 1.1e-26 93.6 12.6 3.7e-26 92.0 12.6 1.9 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_C PF18199.1 CAM38725.1 - 4.3e-24 85.3 0.0 1.6e-23 83.4 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_16 PF13191.6 CAM38725.1 - 1.1e-14 55.2 0.0 5.9e-06 26.8 0.0 6.0 3 0 0 3 3 3 2 AAA ATPase domain AAA PF00004.29 CAM38725.1 - 7.7e-11 42.5 0.0 0.081 13.4 0.0 4.4 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CAM38725.1 - 1.2e-10 41.8 0.1 0.0037 17.5 0.0 4.8 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 CAM38725.1 - 7.5e-07 29.2 0.1 0.0003 20.7 0.1 3.3 2 0 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 CAM38725.1 - 1.2e-06 28.4 0.0 0.11 12.2 0.0 3.8 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 CAM38725.1 - 2.6e-06 27.8 0.0 0.71 10.3 0.0 3.7 3 0 0 3 3 3 1 RNA helicase AAA_30 PF13604.6 CAM38725.1 - 6.5e-06 26.0 0.1 0.022 14.5 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 CAM38725.1 - 8e-06 26.1 0.1 0.12 12.5 0.0 3.9 3 0 0 3 3 3 2 AAA domain IIGP PF05049.13 CAM38725.1 - 1.5e-05 24.2 1.7 0.0098 15.0 0.0 3.0 3 0 0 3 3 3 2 Interferon-inducible GTPase (IIGP) AAA_28 PF13521.6 CAM38725.1 - 1.6e-05 25.3 0.0 1.9 8.7 0.0 4.3 3 0 0 3 3 3 2 AAA domain ABC_tran PF00005.27 CAM38725.1 - 4.2e-05 24.1 8.2 0.0053 17.3 0.0 4.8 5 1 0 5 5 2 1 ABC transporter AAA_lid_7 PF17867.1 CAM38725.1 - 5.7e-05 23.3 0.2 0.00068 19.8 0.0 3.1 2 0 0 2 2 1 1 Midasin AAA lid domain NACHT PF05729.12 CAM38725.1 - 0.0001 22.3 0.8 0.41 10.5 0.0 3.4 3 0 0 3 3 2 2 NACHT domain AAA_18 PF13238.6 CAM38725.1 - 0.00012 22.6 3.1 0.21 12.2 0.0 5.4 5 0 0 5 5 4 1 AAA domain Rad17 PF03215.15 CAM38725.1 - 0.00022 21.2 0.5 0.045 13.7 0.1 3.6 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_14 PF13173.6 CAM38725.1 - 0.00043 20.3 0.0 0.28 11.2 0.0 3.8 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 CAM38725.1 - 0.00066 19.4 0.1 0.038 13.7 0.0 3.2 3 0 0 3 3 2 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 CAM38725.1 - 0.00068 19.4 0.1 0.1 12.3 0.0 3.9 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_25 PF13481.6 CAM38725.1 - 0.00099 18.7 0.4 12 5.4 0.0 4.6 4 0 0 4 4 3 0 AAA domain Sigma54_activat PF00158.26 CAM38725.1 - 0.0012 18.6 0.0 0.25 11.0 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 CAM38725.1 - 0.0017 17.7 0.1 3.2 7.1 0.0 3.3 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI cobW PF02492.19 CAM38725.1 - 0.0017 17.9 3.9 1.4 8.5 0.0 3.8 4 0 0 4 4 3 1 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 CAM38725.1 - 0.0019 17.3 0.0 0.081 12.0 0.0 2.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_21 PF13304.6 CAM38725.1 - 0.0073 16.1 0.0 0.028 14.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Roc PF08477.13 CAM38725.1 - 0.0075 16.5 0.2 5.4 7.3 0.0 3.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 CAM38725.1 - 0.012 15.7 0.1 2.3 8.2 0.0 3.8 4 0 0 4 4 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_PrkA PF08298.11 CAM38725.1 - 0.013 14.4 0.1 0.057 12.3 0.0 2.0 3 0 0 3 3 2 0 PrkA AAA domain DUF815 PF05673.13 CAM38725.1 - 0.013 14.6 0.1 0.31 10.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Guanylate_kin PF00625.21 CAM38725.1 - 0.019 14.6 7.9 0.19 11.4 0.0 3.9 4 0 0 4 4 2 0 Guanylate kinase Zeta_toxin PF06414.12 CAM38725.1 - 0.021 14.1 0.0 0.54 9.5 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin ATP_bind_1 PF03029.17 CAM38725.1 - 0.025 14.3 0.2 2.5 7.8 0.0 3.6 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein MeaB PF03308.16 CAM38725.1 - 0.033 13.2 0.2 0.18 10.8 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SRPRB PF09439.10 CAM38725.1 - 0.034 13.6 4.3 0.11 12.0 0.0 3.0 3 0 0 3 3 2 0 Signal recognition particle receptor beta subunit Nucleo_P87 PF07267.11 CAM38725.1 - 0.038 12.9 0.8 0.077 11.9 0.8 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Septin PF00735.18 CAM38725.1 - 0.058 12.7 0.3 12 5.0 0.0 2.8 3 0 0 3 3 2 0 Septin MMR_HSR1 PF01926.23 CAM38725.1 - 0.15 12.2 0.3 9.7 6.3 0.1 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase SMC_N PF02463.19 CAM38725.1 - 0.2 11.1 0.0 5.2 6.4 0.0 2.8 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain G-alpha PF00503.20 CAM38725.1 - 0.23 10.6 1.7 1.1 8.4 0.0 2.8 3 0 0 3 3 3 0 G-protein alpha subunit ATPase_2 PF01637.18 CAM38725.1 - 0.33 10.8 0.0 0.33 10.8 0.0 4.3 5 0 0 5 5 2 0 ATPase domain predominantly from Archaea Cytidylate_kin PF02224.18 CAM38725.1 - 1.9 8.2 5.2 7.6 6.2 0.0 3.5 3 0 0 3 3 3 0 Cytidylate kinase Glutaredoxin2_C PF04399.13 CAM38725.1 - 2.8 7.8 8.2 4.9 7.0 1.4 4.1 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain zf-CCHC_3 PF13917.6 CAM38726.1 - 2.9e-15 55.9 3.2 2.9e-15 55.9 3.2 1.7 2 0 0 2 2 2 1 Zinc knuckle eIF3g PF12353.8 CAM38726.1 - 0.0011 19.4 1.0 0.0011 19.4 1.0 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G zf-CCHC PF00098.23 CAM38726.1 - 0.074 13.2 1.0 0.12 12.5 1.0 1.4 1 0 0 1 1 1 0 Zinc knuckle Fam20C PF06702.12 CAM38727.2 - 2.5e-06 27.5 0.0 0.014 15.2 0.0 2.3 2 0 0 2 2 2 2 Golgi casein kinase, C-terminal, Fam20 Metallophos PF00149.28 CAM38728.1 - 2.5e-33 116.3 0.0 3.4e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Complex1_LYR PF05347.15 CAM38731.1 - 0.032 14.3 0.1 0.073 13.1 0.1 1.6 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Robl_LC7 PF03259.17 CAM38732.1 - 0.0034 17.1 0.0 0.0052 16.5 0.0 1.5 1 1 0 1 1 1 1 Roadblock/LC7 domain BRCT PF00533.26 CAM38733.1 - 2.2e-07 31.2 0.0 4.8e-06 26.8 0.0 2.7 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain FHA PF00498.26 CAM38733.1 - 3.3e-07 30.6 0.0 7.2e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 FHA domain PTCB-BRCT PF12738.7 CAM38733.1 - 0.00057 19.8 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain RTT107_BRCT_5 PF16770.5 CAM38733.1 - 0.0021 17.9 0.0 0.0036 17.1 0.0 1.4 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 CAM38733.1 - 0.0023 18.3 0.0 0.11 12.9 0.0 2.4 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Kinesin PF00225.23 CAM38735.2 - 8.7e-104 347.0 0.1 1.7e-103 346.0 0.1 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CAM38735.2 - 2.9e-19 69.5 0.0 7e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Pex24p PF06398.11 CAM38735.2 - 4.4e-07 29.2 0.3 4.4e-07 29.2 0.3 1.6 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin DUF1495 PF07381.11 CAM38735.2 - 0.062 13.1 0.0 0.29 11.0 0.0 2.1 2 0 0 2 2 2 0 Winged helix DNA-binding domain (DUF1495) SPX PF03105.19 CAM38735.2 - 1.1 9.1 10.4 2.3 8.1 10.4 1.5 1 0 0 1 1 1 0 SPX domain Cullin_binding PF03556.15 CAM38736.1 - 2.1e-15 57.2 0.7 3.2e-15 56.6 0.7 1.3 1 0 0 1 1 1 1 Cullin binding Gar1 PF04410.14 CAM38737.1 - 5.9e-27 94.3 0.0 7.2e-27 94.1 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region DHHC PF01529.20 CAM38738.1 - 3.8e-15 56.2 6.4 3.8e-15 56.2 6.4 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase YccF PF03733.13 CAM38738.1 - 0.14 12.9 0.7 0.14 12.9 0.7 3.4 4 0 0 4 4 4 0 Inner membrane component domain Coatomer_WDAD PF04053.14 CAM38739.1 - 9.6e-95 318.2 0.0 1.4e-94 317.7 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 CAM38739.1 - 1.8e-94 316.8 0.0 2.9e-94 316.1 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 CAM38739.1 - 4e-41 138.2 17.6 4e-07 30.6 0.1 7.1 6 0 0 6 6 6 6 WD domain, G-beta repeat TPR_2 PF07719.17 CAM38739.1 - 0.028 14.5 0.3 8.2 6.8 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Nucleoporin_N PF08801.11 CAM38739.1 - 0.11 11.3 0.1 0.55 8.9 0.0 2.1 2 0 0 2 2 2 0 Nup133 N terminal like TPR_14 PF13428.6 CAM38739.1 - 0.81 10.7 4.8 33 5.7 0.5 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat ESSS PF10183.9 CAM38740.1 - 1.5e-16 60.5 8.2 3e-16 59.5 8.2 1.6 1 1 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Proteasome PF00227.26 CAM38741.1 - 1.3e-30 106.3 0.0 1.5e-30 106.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit ESSS PF10183.9 CAM38742.1 - 1.5e-16 60.5 8.2 3e-16 59.5 8.2 1.6 1 1 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) adh_short PF00106.25 CAM38743.2 - 8.2e-10 38.5 1.9 4.5e-09 36.0 1.9 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CAM38743.2 - 0.00015 21.4 3.1 0.00054 19.6 3.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 CAM38743.2 - 0.001 18.6 0.1 0.0023 17.4 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Proteasome PF00227.26 CAM38744.1 - 1.1e-30 106.6 0.0 1.2e-30 106.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit PI3_PI4_kinase PF00454.27 CAM38745.2 - 2e-58 198.1 0.1 4.6e-58 197.0 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 CAM38745.2 - 7.4e-40 137.2 0.3 1.5e-39 136.2 0.3 1.6 1 0 0 1 1 1 1 FAT domain FRB_dom PF08771.11 CAM38745.2 - 4.9e-29 100.7 0.3 2e-28 98.7 0.3 2.2 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain DUF3385 PF11865.8 CAM38745.2 - 4.3e-16 59.2 0.0 3.3e-15 56.3 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) FATC PF02260.20 CAM38745.2 - 4e-11 42.5 0.3 1.4e-10 40.8 0.3 2.1 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 CAM38745.2 - 0.00017 21.5 3.5 7.7 7.1 0.0 7.0 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.7 CAM38745.2 - 0.001 19.1 0.5 1.4 8.9 0.0 4.7 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CAM38745.2 - 0.047 14.2 0.1 11 6.6 0.0 4.8 5 0 0 5 5 5 0 HEAT-like repeat ADIP PF11559.8 CAM38746.1 - 0.00019 21.6 5.8 0.00022 21.3 5.8 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Tom22 PF04281.13 CAM38746.1 - 0.00029 20.7 2.0 0.00034 20.4 2.0 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 IFT57 PF10498.9 CAM38746.1 - 0.002 17.2 3.6 0.002 17.2 3.6 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 DUF3450 PF11932.8 CAM38746.1 - 0.0022 17.4 6.0 0.0022 17.4 6.0 1.4 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) BRE1 PF08647.11 CAM38746.1 - 0.0058 16.7 7.3 0.013 15.6 7.3 1.6 1 1 0 1 1 1 1 BRE1 E3 ubiquitin ligase HMMR_C PF15908.5 CAM38746.1 - 0.01 16.1 2.4 0.018 15.3 2.4 1.6 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal GAS PF13851.6 CAM38746.1 - 0.013 14.9 7.7 0.016 14.6 7.7 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Lebercilin PF15619.6 CAM38746.1 - 0.015 15.0 8.9 0.037 13.7 8.9 1.6 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF4061 PF13270.6 CAM38746.1 - 0.024 14.9 2.1 0.22 11.9 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4061) DUF1241 PF06840.11 CAM38746.1 - 0.025 14.2 3.3 0.033 13.8 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) Leu_zip PF15294.6 CAM38746.1 - 0.027 14.0 6.3 0.03 13.8 6.3 1.0 1 0 0 1 1 1 0 Leucine zipper DUF4795 PF16043.5 CAM38746.1 - 0.033 13.8 4.2 0.041 13.5 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) FUSC PF04632.12 CAM38746.1 - 0.043 12.3 1.9 0.049 12.2 1.9 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family FAM76 PF16046.5 CAM38746.1 - 0.044 13.2 3.6 0.051 12.9 3.6 1.1 1 0 0 1 1 1 0 FAM76 protein Wtap PF17098.5 CAM38746.1 - 0.055 13.4 5.9 0.074 13.0 5.9 1.1 1 0 0 1 1 1 0 WTAP/Mum2p family Spc7 PF08317.11 CAM38746.1 - 0.087 11.7 8.5 0.11 11.3 8.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein JAKMIP_CC3 PF16034.5 CAM38746.1 - 0.089 12.7 6.1 0.23 11.4 6.1 1.7 1 1 0 1 1 1 0 JAKMIP CC3 domain DUF948 PF06103.11 CAM38746.1 - 0.11 12.8 0.9 4.4 7.6 0.3 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) FliD_N PF02465.18 CAM38746.1 - 0.11 13.3 4.2 0.19 12.5 4.2 1.5 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus DUF1664 PF07889.12 CAM38746.1 - 0.12 12.5 3.0 0.13 12.3 2.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) GCK PF07802.11 CAM38746.1 - 0.12 12.8 0.2 2.4 8.6 0.1 2.0 1 1 1 2 2 2 0 GCK domain Sec20 PF03908.13 CAM38746.1 - 0.13 12.2 2.0 0.34 10.9 0.6 2.0 1 1 1 2 2 2 0 Sec20 USP8_interact PF08941.10 CAM38746.1 - 0.14 12.0 1.4 0.16 11.8 1.4 1.2 1 0 0 1 1 1 0 USP8 interacting YabA PF06156.13 CAM38746.1 - 0.15 12.8 2.3 0.16 12.6 1.6 1.4 1 1 0 1 1 1 0 Initiation control protein YabA ABC_tran_CTD PF16326.5 CAM38746.1 - 0.2 11.9 10.0 0.095 13.0 5.2 2.4 1 1 1 2 2 2 0 ABC transporter C-terminal domain ERM PF00769.19 CAM38746.1 - 0.21 11.3 11.1 0.23 11.3 11.1 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Prefoldin_2 PF01920.20 CAM38746.1 - 0.23 11.4 8.4 0.11 12.5 3.7 2.2 1 1 1 2 2 2 0 Prefoldin subunit Fib_alpha PF08702.10 CAM38746.1 - 0.49 10.6 3.5 1.2 9.3 0.4 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FapA PF03961.13 CAM38746.1 - 0.57 8.7 4.4 0.86 8.1 4.4 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A DivIC PF04977.15 CAM38746.1 - 0.77 9.6 10.0 2.6 7.9 0.3 2.8 1 1 2 3 3 3 0 Septum formation initiator APG6_N PF17675.1 CAM38746.1 - 0.89 10.1 11.8 6.2 7.4 11.8 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region ZapB PF06005.12 CAM38746.1 - 1.7 9.2 8.9 15 6.1 8.9 2.3 1 1 0 1 1 1 0 Cell division protein ZapB Bap31_Bap29_C PF18035.1 CAM38746.1 - 3.5 7.7 10.2 5.9 7.0 1.1 2.5 2 1 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF4140 PF13600.6 CAM38746.1 - 3.7 8.1 9.1 9.4 6.8 4.7 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Rcd1 PF04078.13 CAM38747.1 - 4e-99 331.1 1.1 4.7e-99 330.9 1.1 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like RRM_1 PF00076.22 CAM38748.1 - 3.2e-29 100.6 0.0 5.1e-14 51.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAM38748.1 - 0.00027 21.0 0.0 0.33 11.1 0.0 3.4 3 1 0 3 3 3 2 RNA recognition motif RRM_3 PF08777.11 CAM38748.1 - 0.00041 20.3 0.0 2.3 8.3 0.0 3.2 3 0 0 3 3 3 2 RNA binding motif RNA_bind PF08675.11 CAM38748.1 - 0.0062 16.5 0.1 0.62 10.1 0.0 3.0 3 1 0 3 3 3 1 RNA binding domain Nup35_RRM_2 PF14605.6 CAM38748.1 - 0.038 14.0 0.0 0.24 11.4 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 CAM38748.1 - 0.094 12.3 0.0 10 5.8 0.0 2.6 2 1 1 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 CAM38748.1 - 0.14 12.4 2.3 7.9 6.7 0.3 3.2 2 2 2 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter Tmemb_170 PF10190.9 CAM38749.1 - 0.0081 16.5 8.8 0.0098 16.2 8.8 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 DUF308 PF03729.13 CAM38749.1 - 0.081 13.3 9.2 6.5 7.2 5.9 2.6 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) TMEM239 PF15841.5 CAM38749.1 - 0.17 11.8 2.3 0.32 10.9 1.6 1.5 1 1 1 2 2 2 0 Transmembrane protein 239 family WD40 PF00400.32 CAM38750.1 - 0.00012 22.8 0.8 0.19 12.7 0.0 4.4 4 0 0 4 4 4 1 WD domain, G-beta repeat ARD PF03079.14 CAM38752.1 - 1.1e-26 93.9 0.1 1.1e-26 93.9 0.1 2.1 2 0 0 2 2 2 1 ARD/ARD' family Cupin_2 PF07883.11 CAM38752.1 - 5.2e-07 29.3 0.0 1.9e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.19 CAM38752.1 - 0.00018 21.4 0.0 0.00034 20.5 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 CAM38752.1 - 0.00039 20.1 0.0 0.00096 18.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_8 PF13621.6 CAM38752.1 - 0.029 14.1 1.6 0.072 12.8 0.0 2.0 2 1 0 2 2 2 0 Cupin-like domain Cupin_6 PF12852.7 CAM38752.1 - 0.033 13.9 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 Cupin Cupin_1 PF00190.22 CAM38752.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Cupin 2OG-FeII_Oxy_5 PF13759.6 CAM38752.1 - 0.15 12.5 0.3 0.41 11.1 0.0 1.9 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase CDC45 PF02724.14 CAM38752.1 - 0.5 8.6 5.3 0.51 8.6 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein PutA_N PF18083.1 CAM38753.1 - 0.058 13.4 2.1 0.13 12.3 0.6 2.4 2 0 0 2 2 2 0 Proline utilization A N-terminal domain cNMP_binding PF00027.29 CAM38754.1 - 4e-08 33.2 0.1 1.5e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain RNA_pol_Rpb2_6 PF00562.28 CAM38755.1 - 1.3e-116 390.0 0.0 2.2e-116 389.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CAM38755.1 - 6.9e-45 153.1 0.9 9.8e-45 152.6 0.9 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 CAM38755.1 - 6.2e-32 109.8 0.2 2.1e-31 108.2 0.2 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 CAM38755.1 - 2.3e-21 76.3 0.1 4.9e-21 75.2 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 CAM38755.1 - 2.8e-19 69.1 1.8 2.8e-19 69.1 1.8 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 CAM38755.1 - 7.5e-19 67.7 0.0 1.5e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 CAM38755.1 - 3.6e-08 33.8 0.3 1.3e-07 32.1 0.3 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 5 WD40 PF00400.32 CAM38756.1 - 7.6e-19 67.7 7.3 3.1e-05 24.6 0.1 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM38756.1 - 0.00014 22.1 0.0 0.46 10.8 0.0 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CAM38756.1 - 0.0024 16.6 1.7 0.27 9.8 0.2 2.8 1 1 2 3 3 3 2 Nucleoporin Nup120/160 DUF1500 PF07389.12 CAM38756.1 - 0.15 12.2 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1500) Hira PF07569.11 CAM38756.1 - 0.35 10.5 3.1 11 5.6 0.2 2.9 2 1 0 3 3 3 0 TUP1-like enhancer of split DOT1 PF08123.13 CAM38757.1 - 2.3e-19 69.7 0.0 3.5e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 CAM38757.1 - 2.4e-05 24.9 0.0 4.4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAM38757.1 - 2.6e-05 24.8 0.0 7e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAM38757.1 - 6.6e-05 22.8 0.0 9.6e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAM38757.1 - 0.0071 16.2 0.0 0.0087 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CAM38757.1 - 0.021 14.8 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 CAM38757.1 - 0.023 15.5 0.0 0.04 14.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 CAM38757.1 - 0.077 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase AdoMet_MTase PF07757.13 CAM38757.1 - 0.086 13.2 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase ADH_zinc_N PF00107.26 CAM38757.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PHO4 PF01384.20 CAM38758.1 - 2.2e-108 362.3 20.4 2.7e-108 362.0 20.4 1.1 1 0 0 1 1 1 1 Phosphate transporter family DUF5520 PF17658.1 CAM38759.1 - 0.015 14.4 0.1 0.021 13.9 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5520) ASF1_hist_chap PF04729.13 CAM38760.1 - 3.1e-46 157.1 0.0 3.8e-46 156.8 0.0 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone BRCA-2_OB1 PF09103.10 CAM38761.2 - 2.2e-24 85.8 0.0 3.5e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA2 PF00634.18 CAM38761.2 - 1.2e-06 28.0 0.0 0.0002 21.0 0.0 2.4 2 0 0 2 2 2 2 BRCA2 repeat zf-RanBP PF00641.18 CAM38761.2 - 0.27 10.6 7.1 0.081 12.3 2.6 2.4 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DUF5521 PF17659.1 CAM38761.2 - 0.29 9.0 0.0 0.43 8.4 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5521) MRG PF05712.13 CAM38762.1 - 0.012 15.0 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 0 MRG Ion_trans_2 PF07885.16 CAM38764.1 - 4.6e-12 45.7 6.5 4.6e-12 45.7 6.5 2.6 3 0 0 3 3 3 1 Ion channel BK_channel_a PF03493.18 CAM38764.1 - 1.8e-09 37.7 0.0 5.6e-09 36.1 0.0 1.9 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit PGK PF00162.19 CAM38765.2 - 4.3e-155 516.3 0.0 5e-155 516.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase NB-ARC PF00931.22 CAM38766.1 - 8.5e-07 28.4 0.0 0.035 13.3 0.0 2.2 1 1 1 2 2 2 2 NB-ARC domain AAA_16 PF13191.6 CAM38766.1 - 3.2e-05 24.4 0.2 0.00046 20.6 0.2 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 CAM38766.1 - 0.042 13.9 0.0 0.18 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CAM38766.1 - 0.12 12.3 0.1 1.3 8.9 0.0 2.2 1 1 1 2 2 2 0 NACHT domain MORN PF02493.20 CAM38767.1 - 2.5e-10 39.6 16.2 1.8e-06 27.5 0.0 6.6 6 0 0 6 6 6 3 MORN repeat Ferritin_2 PF13668.6 CAM38768.2 - 0.19 11.9 0.1 0.51 10.5 0.0 1.7 2 0 0 2 2 2 0 Ferritin-like domain DUF1736 PF08409.11 CAM38769.2 - 1.1e-18 67.0 0.5 3.4e-18 65.4 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1736) NifW PF03206.14 CAM38770.1 - 0.046 14.2 2.4 0.18 12.3 0.0 2.5 2 0 0 2 2 2 0 Nitrogen fixation protein NifW CBM32 PF18344.1 CAM38770.1 - 0.056 13.3 0.4 0.12 12.2 0.4 1.5 1 0 0 1 1 1 0 Carbohydrate binding module family 32 Peptidase_S46 PF10459.9 CAM38770.1 - 0.065 11.9 12.3 0.089 11.4 12.3 1.1 1 0 0 1 1 1 0 Peptidase S46 Mto2_bdg PF12808.7 CAM38770.1 - 0.12 12.7 3.5 0.28 11.5 0.3 2.8 3 0 0 3 3 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Sec20 PF03908.13 CAM38770.1 - 0.12 12.3 5.2 0.21 11.5 4.1 2.1 1 1 1 2 2 2 0 Sec20 PKcGMP_CC PF16808.5 CAM38770.1 - 0.2 11.5 2.3 31 4.5 0.0 3.7 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TMF_TATA_bd PF12325.8 CAM38770.1 - 0.32 11.2 19.7 0.096 12.9 4.9 2.8 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 CAM38770.1 - 0.34 9.8 14.3 0.14 11.0 11.6 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF2408 PF10303.9 CAM38770.1 - 0.5 10.9 11.9 0.82 10.2 2.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) RILP PF11461.8 CAM38770.1 - 0.61 10.3 4.9 1.9 8.8 4.0 2.2 1 1 1 2 2 2 0 Rab interacting lysosomal protein DUF948 PF06103.11 CAM38770.1 - 0.74 10.1 7.0 0.27 11.5 1.5 2.9 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF641 PF04859.12 CAM38770.1 - 1.2 9.5 8.7 0.92 9.8 4.8 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF16 PF01519.16 CAM38770.1 - 3.1 8.3 8.1 7.8 7.0 0.4 3.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 CENP-Q PF13094.6 CAM38770.1 - 4.8 7.4 16.4 34 4.6 15.0 2.9 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit CorA PF01544.18 CAM38770.1 - 5.8 6.1 9.8 2.4 7.4 5.9 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein GAS PF13851.6 CAM38770.1 - 6.1 6.2 12.5 12 5.1 12.0 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4763 PF15960.5 CAM38770.1 - 9.7 5.4 12.5 1.5 8.0 8.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) IFT57 PF10498.9 CAM38773.2 - 9.6e-05 21.5 1.7 9.6e-05 21.5 1.7 2.1 3 0 0 3 3 3 1 Intra-flagellar transport protein 57 DUF4726 PF15855.5 CAM38773.2 - 0.023 14.9 0.1 0.54 10.5 0.0 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4726) DUF5344 PF17279.2 CAM38773.2 - 0.064 13.8 1.7 0.53 10.9 1.0 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5344) LemA PF04011.12 CAM38773.2 - 0.16 11.8 3.7 0.087 12.7 0.6 2.0 2 0 0 2 2 2 0 LemA family OmpH PF03938.14 CAM38773.2 - 0.24 11.7 12.7 0.12 12.7 7.9 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) RecG_N PF17190.4 CAM38773.2 - 1.5 9.6 6.5 0.75 10.6 0.4 2.6 2 0 0 2 2 2 0 RecG N-terminal helical domain HAUS6_N PF14661.6 CAM38773.2 - 6.3 6.3 9.4 0.33 10.5 0.6 2.7 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 6 N-terminus KASH_CCD PF14662.6 CAM38774.2 - 9.8e-19 67.9 200.9 0.00032 20.6 31.1 9.2 2 1 10 12 12 12 11 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 CAM38774.2 - 1.6e-15 57.4 221.4 0.0014 18.6 17.9 11.5 2 1 12 14 14 14 12 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Taxilin PF09728.9 CAM38774.2 - 2.1e-15 56.7 158.0 0.032 13.4 6.2 12.9 2 1 10 12 12 12 11 Myosin-like coiled-coil protein ERM PF00769.19 CAM38774.2 - 1.6e-12 47.7 287.6 0.0072 16.2 25.7 9.0 2 1 10 12 12 12 10 Ezrin/radixin/moesin family GAS PF13851.6 CAM38774.2 - 1.3e-11 44.2 202.0 0.02 14.3 19.0 13.3 2 1 10 12 12 12 11 Growth-arrest specific micro-tubule binding Rootletin PF15035.6 CAM38774.2 - 1.8e-09 37.9 186.8 0.5 10.4 21.1 13.8 1 1 13 14 14 14 3 Ciliary rootlet component, centrosome cohesion DUF2353 PF09789.9 CAM38774.2 - 3.2e-07 30.0 148.0 0.0046 16.4 22.7 7.3 2 1 5 7 7 7 6 Uncharacterized coiled-coil protein (DUF2353) Nup88 PF10168.9 CAM38774.2 - 2.2e-06 25.8 155.5 0.013 13.4 9.7 10.1 2 1 10 12 12 12 10 Nuclear pore component PRKG1_interact PF15898.5 CAM38774.2 - 6e-06 27.1 193.1 0.078 13.9 14.4 13.4 2 2 11 13 13 13 6 cGMP-dependent protein kinase interacting domain Syntaxin_2 PF14523.6 CAM38774.2 - 9.2e-06 26.0 69.8 0.15 12.4 2.5 10.0 2 1 10 13 13 13 8 Syntaxin-like protein CLZ PF16526.5 CAM38774.2 - 1e-05 25.8 177.2 1.3 9.5 3.0 15.8 2 1 13 15 15 15 6 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TPR_MLP1_2 PF07926.12 CAM38774.2 - 1e-05 25.6 245.5 0.16 12.1 19.6 10.6 4 2 9 13 13 13 8 TPR/MLP1/MLP2-like protein UPF0242 PF06785.11 CAM38774.2 - 0.00024 21.3 7.8 0.00024 21.3 7.8 12.9 2 1 9 11 11 10 2 Uncharacterised protein family (UPF0242) N-terminus ZapB PF06005.12 CAM38774.2 - 0.00039 20.8 268.1 0.24 11.9 9.5 17.4 10 4 7 17 17 16 8 Cell division protein ZapB GIT_CC PF16559.5 CAM38774.2 - 0.00045 20.0 104.8 2.3 8.1 1.0 15.6 11 3 5 16 16 15 6 GIT coiled-coil Rho guanine nucleotide exchange factor CENP-H PF05837.12 CAM38774.2 - 0.0021 18.5 180.2 0.13 12.7 11.4 12.4 3 1 9 14 14 13 5 Centromere protein H (CENP-H) ADIP PF11559.8 CAM38774.2 - 0.0047 17.0 189.2 0.088 12.9 9.7 13.0 2 1 13 15 15 15 8 Afadin- and alpha -actinin-Binding Fez1 PF06818.15 CAM38774.2 - 0.005 17.3 186.7 0.047 14.1 28.5 8.0 1 1 6 7 7 6 2 Fez1 TolA_bind_tri PF16331.5 CAM38774.2 - 0.054 13.6 168.3 0.31 11.1 1.3 19.9 2 2 17 21 21 21 0 TolA binding protein trimerisation YAcAr PF10686.9 CAM38774.2 - 0.075 13.0 19.1 4.1e+02 1.0 0.0 12.2 14 0 0 14 14 14 0 YspA, cpYpsA-related SLOG family JIP_LZII PF16471.5 CAM38774.2 - 0.093 12.9 156.0 2.8 8.2 3.4 17.3 16 1 0 17 17 17 0 JNK-interacting protein leucine zipper II BRE1 PF08647.11 CAM38774.2 - 0.099 12.7 165.9 0.039 14.0 6.1 13.3 4 2 4 11 11 11 0 BRE1 E3 ubiquitin ligase PHM7_cyt PF14703.6 CAM38774.2 - 0.12 12.6 94.0 1.5 9.1 6.7 9.0 2 1 6 10 10 10 0 Cytosolic domain of 10TM putative phosphate transporter Laminin_I PF06008.14 CAM38774.2 - 0.15 11.8 173.3 0.8 9.4 20.2 8.8 2 1 5 8 8 8 0 Laminin Domain I DUF4164 PF13747.6 CAM38774.2 - 0.5 10.7 224.3 5.5 7.3 9.1 16.7 2 1 14 16 16 16 0 Domain of unknown function (DUF4164) MCC-bdg_PDZ PF10506.9 CAM38774.2 - 0.79 9.8 173.9 0.32 11.1 2.3 14.9 15 0 0 15 15 14 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF812 PF05667.11 CAM38774.2 - 3.2 6.5 172.9 0.025 13.5 31.0 6.8 1 1 5 7 7 7 0 Protein of unknown function (DUF812) DUF1664 PF07889.12 CAM38774.2 - 5.4 7.1 68.6 2.9 7.9 0.9 11.0 2 1 11 14 14 14 0 Protein of unknown function (DUF1664) Amastin PF07344.11 CAM38775.1 - 4.3e-50 169.6 15.0 6.1e-50 169.1 15.0 1.2 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF4293 PF14126.6 CAM38775.1 - 0.63 10.3 7.7 1.4 9.2 7.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) Amastin PF07344.11 CAM38776.1 - 2.1e-51 173.8 15.0 2.5e-51 173.6 15.0 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF4293 PF14126.6 CAM38776.1 - 0.086 13.1 7.7 0.18 12.1 7.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) Amastin PF07344.11 CAM38777.1 - 5.1e-55 185.6 9.6 6.4e-55 185.3 9.6 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF423 PF04241.15 CAM38777.1 - 0.055 13.7 4.2 3.2 8.0 2.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF423) Amastin PF07344.11 CAM38778.2 - 1.9e-53 180.5 14.9 2.3e-53 180.2 14.9 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Amastin PF07344.11 CAM38780.1 - 1.2e-53 181.1 9.0 1.5e-53 180.8 9.0 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF423 PF04241.15 CAM38780.1 - 0.0046 17.1 5.4 0.34 11.1 3.9 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF423) Methyltransf_12 PF08242.12 CAM38783.1 - 7.7e-15 55.4 0.0 9.6e-14 51.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAM38783.1 - 1.4e-14 54.2 0.0 2.1e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAM38783.1 - 3e-13 50.2 0.5 5.3e-10 39.8 0.0 3.5 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAM38783.1 - 3.7e-13 50.0 0.1 4.6e-05 24.1 0.0 3.3 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.6 CAM38783.1 - 6.3e-12 45.5 0.0 4.9e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain NodS PF05401.11 CAM38783.1 - 0.0041 16.8 0.1 0.0092 15.6 0.0 1.6 2 0 0 2 2 2 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 CAM38783.1 - 0.025 13.9 0.0 0.2 10.9 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 CAM38783.1 - 0.074 12.5 0.0 0.57 9.6 0.0 2.5 3 1 0 3 3 3 0 Putative methyltransferase Methyltransf_24 PF13578.6 CAM38783.1 - 0.12 13.4 0.0 0.4 11.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain zf-rbx1 PF12678.7 CAM38784.1 - 1.4e-24 86.1 15.6 2.1e-24 85.6 15.6 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CAM38784.1 - 2.6e-17 62.6 11.4 3.2e-17 62.4 11.4 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 CAM38784.1 - 9.8e-06 25.8 17.8 0.00047 20.4 17.8 2.4 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CAM38784.1 - 0.001 18.8 16.0 0.085 12.7 16.0 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CAM38784.1 - 0.012 15.5 15.5 0.075 12.9 14.1 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CAM38784.1 - 0.08 13.0 8.7 0.17 11.9 8.7 1.6 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CAM38784.1 - 0.098 12.5 13.8 1.2 9.1 8.4 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CAM38784.1 - 0.26 10.9 16.6 0.067 12.8 4.6 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 CAM38784.1 - 2.8 7.8 16.2 1.1e+02 2.7 16.2 2.5 1 1 0 1 1 1 0 RING-like zinc finger FANCL_C PF11793.8 CAM38784.1 - 3.7 7.8 12.8 27 5.0 12.9 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_5 PF14634.6 CAM38784.1 - 5.8 7.0 14.7 74 3.4 14.8 2.4 1 1 0 1 1 1 0 zinc-RING finger domain bZIP_1 PF00170.21 CAM38786.1 - 0.023 14.8 0.1 1.7 8.8 0.0 2.8 2 0 0 2 2 2 0 bZIP transcription factor GvpD PF07088.11 CAM38786.1 - 0.024 13.3 0.0 0.032 12.9 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein OmpH PF03938.14 CAM38786.1 - 0.038 14.3 2.8 3.8 7.9 0.1 2.5 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Tup_N PF08581.10 CAM38786.1 - 0.08 13.3 2.9 25 5.2 0.1 3.4 3 0 0 3 3 3 0 Tup N-terminal ALIX_LYPXL_bnd PF13949.6 CAM38787.1 - 1.8e-05 24.2 2.1 2.4e-05 23.8 2.1 1.1 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV HEPN_Cthe2314 PF18730.1 CAM38787.1 - 0.004 17.2 0.3 0.0095 16.0 0.1 1.7 2 0 0 2 2 2 1 Cthe_2314-like HEPN Cep57_CLD PF14073.6 CAM38787.1 - 0.05 13.6 2.7 0.085 12.9 2.7 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 DUF948 PF06103.11 CAM38787.1 - 0.075 13.3 0.1 27 5.1 0.0 3.1 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.11 CAM38787.1 - 0.087 13.2 0.1 3.2 8.2 0.0 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) OmpH PF03938.14 CAM38787.1 - 0.11 12.9 3.1 0.076 13.4 1.3 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Nore1-SARAH PF16517.5 CAM38787.1 - 0.11 12.4 0.4 0.22 11.5 0.4 1.5 1 0 0 1 1 1 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain CENP-H PF05837.12 CAM38787.1 - 1.9 9.0 6.1 1.1 9.7 0.1 2.7 2 1 1 3 3 3 0 Centromere protein H (CENP-H) SNARE PF05739.19 CAM38788.1 - 1.5e-07 31.3 1.9 1.5e-07 31.3 1.9 1.8 2 0 0 2 2 2 1 SNARE domain TrpBP PF02081.15 CAM38788.1 - 0.0075 16.1 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Tryptophan RNA-binding attenuator protein Syntaxin-6_N PF09177.11 CAM38788.1 - 0.037 14.6 4.7 0.049 14.2 0.7 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal End3 PF12761.7 CAM38788.1 - 0.095 12.9 4.2 0.95 9.6 0.7 2.1 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 WD40 PF00400.32 CAM38790.1 - 4.7e-23 81.0 11.6 7.9e-09 36.0 0.0 6.7 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM38790.1 - 9.4e-06 25.8 0.1 0.0096 16.2 0.0 3.7 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CAM38790.1 - 0.00012 20.9 1.8 0.62 8.6 0.0 3.8 3 2 2 5 5 5 3 Nucleoporin Nup120/160 UDG PF03167.19 CAM38790.1 - 0.028 14.4 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 Uracil DNA glycosylase superfamily baeRF_family2 PF18844.1 CAM38790.1 - 0.034 14.2 0.2 0.064 13.3 0.2 1.5 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 2 tRNA_bind_2 PF13725.6 CAM38791.1 - 0.17 11.5 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Possible tRNA binding domain MFS_1 PF07690.16 CAM38792.1 - 5.8e-20 71.5 29.3 5.8e-20 71.5 29.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CAM38792.1 - 0.23 10.3 29.8 0.11 11.4 10.1 2.2 2 0 0 2 2 2 0 Sugar (and other) transporter PgaD PF13994.6 CAM38793.1 - 0.015 15.4 0.4 0.029 14.4 0.4 1.6 1 0 0 1 1 1 0 PgaD-like protein DUF3043 PF11241.8 CAM38793.1 - 2.8 7.9 4.8 0.37 10.8 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) Peptidase_C2 PF00648.21 CAM38796.2 - 3.4e-36 124.8 0.0 8e-36 123.6 0.0 1.6 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 CAM38796.2 - 1.8e-34 119.0 0.0 7.4e-09 36.0 0.0 7.0 6 1 0 6 6 6 5 Calpain large subunit, domain III Thioredoxin_2 PF13098.6 CAM38796.2 - 0.16 12.5 1.6 2 8.9 0.7 2.6 2 0 0 2 2 2 0 Thioredoxin-like domain Topoisom_bac PF01131.20 CAM38797.2 - 1.1e-75 255.3 0.0 1.9e-75 254.5 0.0 1.4 1 1 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CAM38797.2 - 6.1e-15 55.3 0.0 1.5e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 CAM38797.2 - 0.014 15.9 0.0 0.081 13.4 0.0 2.2 2 0 0 2 2 2 0 Toprim domain Sec3_C PF09763.9 CAM38797.2 - 0.052 11.9 0.1 0.15 10.4 0.0 1.6 2 0 0 2 2 2 0 Exocyst complex component Sec3 FliD_C PF07195.12 CAM38797.2 - 0.078 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus FleQ PF06490.11 CAM38797.2 - 0.097 13.1 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ Guanylate_cyc PF00211.20 CAM38798.2 - 0.0002 21.0 0.0 0.00052 19.7 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF5411 PF17424.2 CAM38798.2 - 0.63 10.0 2.8 1.4 8.8 2.8 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5411) Pkinase PF00069.25 CAM38799.2 - 3.7e-54 183.9 0.0 5.9e-54 183.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM38799.2 - 1e-31 110.2 0.0 1.7e-31 109.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Adenyl_cycl_N PF12633.7 CAM38799.2 - 9.7e-13 48.5 0.0 1.7e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate cyclase NT domain Guanylate_cyc PF00211.20 CAM38799.2 - 0.00014 21.6 0.0 0.00024 20.8 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Kdo PF06293.14 CAM38799.2 - 0.0027 17.1 0.0 0.0056 16.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CAM38799.2 - 0.0049 16.2 0.0 0.012 15.0 0.0 1.6 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CAM38799.2 - 0.0082 15.0 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 CAM38799.2 - 0.11 12.1 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RPN6_N PF18055.1 CAM38800.1 - 0.0093 16.3 1.3 0.81 10.1 0.0 3.5 4 0 0 4 4 4 1 26S proteasome regulatory subunit RPN6 N-terminal domain Pkinase PF00069.25 CAM38801.2 - 1.3e-36 126.4 0.0 2e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM38801.2 - 2.2e-13 50.1 0.0 5.9e-10 38.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CAM38801.2 - 0.028 13.8 0.0 4.1 6.6 0.0 2.2 2 0 0 2 2 2 0 Kinase-like LRR_4 PF12799.7 CAM38802.1 - 3.4e-11 43.2 8.7 0.045 14.2 0.1 7.4 6 3 2 8 8 8 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CAM38802.1 - 3.7e-08 32.8 16.6 0.89 9.8 0.1 10.7 13 0 0 13 13 13 3 Leucine Rich repeat LRR_8 PF13855.6 CAM38802.1 - 0.00021 21.0 13.0 1.9 8.3 0.0 7.7 6 2 3 9 9 9 3 Leucine rich repeat LRR_1 PF00560.33 CAM38802.1 - 0.049 14.2 14.5 1.5e+02 3.6 0.0 9.1 13 0 0 13 13 13 0 Leucine Rich Repeat DUF2478 PF10649.9 CAM38802.1 - 0.055 13.1 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2478) PUF PF00806.19 CAM38803.1 - 0.0058 16.2 3.3 7.8 6.4 0.0 5.7 6 1 1 7 7 7 1 Pumilio-family RNA binding repeat CHAT PF12770.7 CAM38804.2 - 3.1e-60 204.0 0.2 6.7e-60 203.0 0.2 1.6 1 0 0 1 1 1 1 CHAT domain LRR_6 PF13516.6 CAM38804.2 - 0.065 13.3 2.6 8.4 6.7 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich repeat TPR_12 PF13424.6 CAM38804.2 - 2.2 8.6 18.4 4.1 7.8 3.4 5.0 3 2 3 6 6 6 0 Tetratricopeptide repeat Vault PF01505.18 CAM38806.1 - 1.8e-28 98.4 0.3 1e-11 44.8 0.1 4.5 4 0 0 4 4 4 3 Major Vault Protein repeat domain Vault_2 PF17794.1 CAM38806.1 - 7e-11 42.3 2.6 3.7e-05 24.0 0.1 4.2 3 1 0 3 3 3 2 Major Vault Protein repeat domain Vault_4 PF17796.1 CAM38806.1 - 5.7e-06 26.3 0.1 0.00017 21.6 0.1 3.0 4 0 0 4 4 4 1 Major Vault Protein repeat domain SNURF PF07192.11 CAM38806.1 - 0.05 13.4 0.2 0.14 12.0 0.2 1.7 1 0 0 1 1 1 0 SNURF/RPN4 protein NopRA1 PF16201.5 CAM38808.1 - 0.023 14.3 0.1 0.046 13.3 0.1 1.4 1 0 0 1 1 1 0 Nucleolar pre-ribosomal-associated protein 1 ELYS PF13934.6 CAM38808.1 - 0.029 14.4 1.3 0.33 10.9 0.3 2.6 2 1 0 2 2 2 0 Nuclear pore complex assembly Gasdermin_C PF17708.1 CAM38808.1 - 0.049 13.7 1.5 0.28 11.3 0.1 2.7 3 0 0 3 3 3 0 Gasdermin PUB domain EF-hand_7 PF13499.6 CAM38809.1 - 3.8e-11 43.3 0.1 7.8e-06 26.2 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CAM38809.1 - 1.4e-08 34.0 1.3 0.0077 16.1 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CAM38809.1 - 2.9e-07 29.6 0.0 0.016 14.7 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CAM38809.1 - 4.2e-07 29.7 0.1 0.0014 18.4 0.1 3.2 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 CAM38809.1 - 5.5e-06 26.6 0.4 0.00017 21.9 0.0 2.8 2 1 1 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.9 CAM38809.1 - 0.015 15.6 0.0 1.6 9.1 0.0 2.3 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Dehydratase_SU PF02287.15 CAM38809.1 - 0.039 14.0 0.0 0.062 13.4 0.0 1.3 1 0 0 1 1 1 0 Dehydratase small subunit DUF384 PF04064.13 CAM38809.1 - 0.18 11.7 2.7 1.1 9.2 0.3 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF384) Actin PF00022.19 CAM38810.1 - 5.6e-35 120.7 0.0 9.7e-34 116.7 0.0 2.1 1 1 0 1 1 1 1 Actin Hexokinase_2 PF03727.16 CAM38811.1 - 4e-61 206.5 0.0 5.9e-61 205.9 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CAM38811.1 - 2.3e-60 203.9 0.0 3.2e-60 203.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase HZS_alpha PF18582.1 CAM38811.1 - 0.081 13.4 0.0 0.2 12.2 0.0 1.6 1 0 0 1 1 1 0 Hydrazine synthase alpha subunit middle domain PPR_2 PF13041.6 CAM38812.1 - 2.6e-12 46.7 2.3 1.3e-06 28.5 0.1 3.9 4 0 0 4 4 4 2 PPR repeat family PPR_3 PF13812.6 CAM38812.1 - 6.2e-11 42.2 0.1 1.1e-06 28.6 0.0 4.2 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR_long PF17177.4 CAM38812.1 - 6.9e-06 25.6 0.2 0.0033 16.8 0.0 3.3 3 1 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 CAM38812.1 - 0.0016 18.6 2.4 32 5.1 0.1 6.2 7 0 0 7 7 7 0 PPR repeat PPR_1 PF12854.7 CAM38812.1 - 0.0099 15.6 0.0 0.83 9.4 0.0 3.0 2 0 0 2 2 2 1 PPR repeat TPR_14 PF13428.6 CAM38812.1 - 0.049 14.5 0.1 8.1 7.6 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ECSIT PF06239.11 CAM38812.1 - 0.082 12.0 0.0 0.26 10.4 0.0 1.8 2 0 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway GMP_synt_C PF00958.22 CAM38812.1 - 0.11 12.5 0.1 4.7 7.3 0.0 2.6 2 0 0 2 2 2 0 GMP synthase C terminal domain Pkinase PF00069.25 CAM38813.1 - 4.6e-48 163.9 0.0 6e-47 160.2 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM38813.1 - 5.6e-30 104.5 0.4 1.9e-21 76.6 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase RIO1 PF01163.22 CAM38813.1 - 0.00068 19.3 0.2 0.0013 18.3 0.2 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CAM38813.1 - 0.033 14.1 8.3 1.4 8.8 0.0 3.7 2 2 1 3 3 3 0 Phosphotransferase enzyme family zf-U1 PF06220.12 CAM38818.1 - 9.1e-05 22.2 4.8 0.00026 20.7 4.8 1.8 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.8 CAM38818.1 - 0.0045 17.3 0.4 0.012 15.8 0.4 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AKAP95 PF04988.12 CAM38818.1 - 0.0071 16.6 0.6 0.01 16.1 0.6 1.2 1 0 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) cIII PF08134.11 CAM38818.1 - 0.011 15.5 0.1 0.021 14.6 0.1 1.4 1 0 0 1 1 1 0 cIII protein family Vps51 PF08700.11 CAM38819.1 - 1.6e-24 85.8 1.7 5.4e-24 84.1 1.7 1.9 1 0 0 1 1 1 1 Vps51/Vps67 Sec5 PF15469.6 CAM38819.1 - 4.8e-08 33.0 0.1 9.9e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 Exocyst complex component Sec5 Dor1 PF04124.12 CAM38819.1 - 2.7e-07 29.6 3.6 4.4e-07 28.9 3.6 1.3 1 0 0 1 1 1 1 Dor1-like family Vps53_N PF04100.12 CAM38819.1 - 3.6e-05 22.9 1.8 7e-05 22.0 1.8 1.4 1 0 0 1 1 1 1 Vps53-like, N-terminal COG2 PF06148.11 CAM38819.1 - 0.0001 22.4 1.8 0.0001 22.4 1.8 2.3 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps54_N PF10475.9 CAM38819.1 - 0.00054 19.3 3.5 0.00099 18.5 3.5 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex COG5 PF10392.9 CAM38819.1 - 0.00082 19.6 2.6 0.0039 17.4 2.8 2.1 2 0 0 2 2 1 1 Golgi transport complex subunit 5 CENP-F_leu_zip PF10473.9 CAM38819.1 - 0.0046 17.0 4.1 0.011 15.7 4.1 1.6 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Zw10 PF06248.13 CAM38819.1 - 0.04 12.5 0.7 0.066 11.8 0.7 1.3 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Occludin_ELL PF07303.13 CAM38819.1 - 0.061 14.1 0.2 0.21 12.3 0.2 1.9 1 0 0 1 1 1 0 Occludin homology domain BLOC1_2 PF10046.9 CAM38819.1 - 0.08 13.2 1.6 0.18 12.1 0.6 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SEO_N PF14576.6 CAM38819.1 - 0.085 12.0 0.6 0.16 11.1 0.6 1.4 1 0 0 1 1 1 0 Sieve element occlusion N-terminus DUF1664 PF07889.12 CAM38819.1 - 0.54 10.3 2.8 0.62 10.1 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 CAM38819.1 - 4.6 7.8 6.5 0.99 9.9 0.6 3.0 4 0 0 4 4 3 0 Nucleopolyhedrovirus P10 protein FlgN PF05130.12 CAM38819.1 - 6.4 7.3 8.5 1.3 9.5 2.6 2.8 2 1 0 2 2 2 0 FlgN protein Peptidase_M16 PF00675.20 CAM38820.1 - 5.1e-09 36.3 0.0 9.4e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CAM38820.1 - 0.0019 18.3 0.2 0.011 15.8 0.0 2.4 3 1 0 3 3 3 1 Peptidase M16 inactive domain DUF2922 PF11148.8 CAM38820.1 - 0.13 12.0 0.1 0.25 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) MCU PF04678.13 CAM38821.1 - 2.9e-20 73.1 1.2 3.5e-20 72.8 1.2 1.2 1 0 0 1 1 1 1 Mitochondrial calcium uniporter rve PF00665.26 CAM38821.1 - 0.082 13.1 1.3 0.1 12.8 0.2 1.7 2 0 0 2 2 2 0 Integrase core domain CCDC92 PF14916.6 CAM38822.1 - 0.039 13.7 0.2 0.089 12.6 0.2 1.6 1 0 0 1 1 1 0 Coiled-coil domain of unknown function ADIP PF11559.8 CAM38822.1 - 1.8 8.7 7.3 2.7 8.1 7.3 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Acetyltransf_6 PF13480.7 CAM38822.1 - 9.8 6.3 6.9 1.6 8.9 1.6 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain RPAP2_Rtr1 PF04181.13 CAM38823.1 - 2.2e-07 31.1 0.0 1.1e-05 25.7 0.0 2.5 1 1 0 1 1 1 1 Rtr1/RPAP2 family DUF667 PF05018.13 CAM38824.2 - 1.9e-92 308.1 0.6 2.1e-92 307.9 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) UCH PF00443.29 CAM38826.1 - 2.3e-43 148.5 0.4 3e-43 148.2 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CAM38826.1 - 5.9e-19 68.8 2.7 2.1e-18 67.0 2.7 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Alpha-2-MRAP_N PF06400.11 CAM38826.1 - 0.007 16.3 1.6 0.016 15.2 1.6 1.5 1 0 0 1 1 1 1 Alpha-2-macroglobulin RAP, N-terminal domain Piwi PF02171.17 CAM38827.1 - 3.7e-09 36.3 0.0 5.4e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Piwi domain Pyr_redox_2 PF07992.14 CAM38828.2 - 2.9e-10 39.9 0.4 1.8e-05 24.1 0.1 3.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CAM38828.2 - 1.3e-05 25.4 0.0 8e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 CAM38828.2 - 0.0004 20.4 0.0 0.0011 19.0 0.0 1.8 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 CAM38828.2 - 0.0017 18.9 0.0 0.19 12.3 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 CAM38828.2 - 0.062 13.4 0.3 67 3.5 0.0 3.4 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 CAM38828.2 - 0.07 12.4 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Thi4 family TFIIA PF03153.13 CAM38829.1 - 0.046 13.7 15.5 0.058 13.4 15.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PI3K_p85B PF02192.16 CAM38829.1 - 0.09 12.5 0.1 0.65 9.8 0.0 2.3 2 0 0 2 2 2 0 PI3-kinase family, p85-binding domain Borrelia_P83 PF05262.11 CAM38829.1 - 0.16 10.4 6.3 0.17 10.4 6.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein GAGA_bind PF06217.12 CAM38829.1 - 1.3 9.3 9.2 2 8.7 9.2 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family TMEM189_B_dmain PF10520.9 CAM38830.1 - 8.3e-65 218.1 1.5 1.1e-64 217.7 1.5 1.1 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain FA_hydroxylase PF04116.13 CAM38830.1 - 0.017 15.4 4.6 0.2 12.0 2.7 2.2 1 1 1 2 2 2 0 Fatty acid hydroxylase superfamily IBV_3A PF03617.13 CAM38830.1 - 0.019 15.0 0.7 0.04 13.9 0.7 1.5 1 0 0 1 1 1 0 IBV 3A protein Vps35 PF03635.17 CAM38833.1 - 3.1e-212 707.1 0.0 3.6e-212 706.9 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Fib_alpha PF08702.10 CAM38834.1 - 0.047 13.9 6.2 0.092 12.9 2.0 2.8 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family BRE1 PF08647.11 CAM38834.1 - 0.11 12.5 0.0 0.11 12.5 0.0 3.5 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase FlxA PF14282.6 CAM38834.1 - 0.16 12.0 14.1 0.28 11.2 2.5 3.3 2 1 1 3 3 3 0 FlxA-like protein TPR_MLP1_2 PF07926.12 CAM38834.1 - 0.76 9.8 31.5 0.13 12.3 0.9 3.3 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Laminin_II PF06009.12 CAM38834.1 - 1.4 8.9 7.1 1.4 9.0 0.8 3.1 1 1 1 2 2 2 0 Laminin Domain II Tropomyosin PF00261.20 CAM38834.1 - 1.6 8.0 26.9 1 8.7 10.4 4.2 3 1 1 4 4 4 0 Tropomyosin GAS PF13851.6 CAM38834.1 - 1.8 7.9 15.8 0.044 13.1 3.3 3.2 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 CAM38834.1 - 7.9 6.7 19.4 2.7 8.2 3.0 3.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding NPV_P10 PF05531.12 CAM38834.1 - 8.2 7.0 7.7 15 6.1 0.9 3.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 CAM38834.1 - 8.8 5.1 23.3 2 7.2 9.3 2.5 2 1 1 3 3 3 0 Spc7 kinetochore protein CH PF00307.31 CAM38836.1 - 0.099 12.8 0.1 0.18 12.0 0.1 1.5 1 1 0 1 1 1 0 Calponin homology (CH) domain TPR_14 PF13428.6 CAM38839.1 - 4.5e-16 58.2 36.6 0.021 15.6 0.2 9.9 5 3 4 9 9 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 CAM38839.1 - 3e-14 53.3 19.9 4.2e-05 24.0 0.0 7.0 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 CAM38839.1 - 6.1e-12 44.7 22.3 0.011 15.8 0.1 8.3 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 CAM38839.1 - 1e-11 44.1 10.1 0.022 14.6 0.1 6.5 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 CAM38839.1 - 1.6e-07 31.5 24.1 0.15 12.4 0.2 6.3 4 2 1 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.6 CAM38839.1 - 8.6e-07 29.5 37.3 0.00036 21.1 0.1 7.5 5 2 1 6 6 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 CAM38839.1 - 9.1e-07 29.0 12.5 0.24 11.6 0.0 5.2 4 2 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CAM38839.1 - 1.7e-05 24.5 12.2 3.6 7.8 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 CAM38839.1 - 6.2e-05 22.9 6.4 5.5 7.5 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 CAM38839.1 - 9.5e-05 22.1 10.4 0.086 12.7 0.2 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 CAM38839.1 - 0.0071 16.5 0.4 0.0071 16.5 0.4 6.1 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 CAM38839.1 - 0.07 12.8 7.4 25 4.7 0.0 5.3 5 0 0 5 5 5 0 TPR repeat TPR_17 PF13431.6 CAM38839.1 - 0.079 13.4 7.0 1.3e+02 3.3 0.0 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 CAM38839.1 - 0.11 12.5 0.0 13 5.9 0.0 2.9 3 0 0 3 3 3 0 Putative TPR-like repeat TPR_20 PF14561.6 CAM38839.1 - 7.4 7.0 6.3 23 5.4 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat La PF05383.17 CAM38840.1 - 9.8e-22 76.8 0.0 2.1e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 CAM38840.1 - 1.1e-06 28.3 0.3 0.00012 21.8 0.1 3.1 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAM38840.1 - 0.00065 19.8 0.1 0.02 15.0 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif RRM_3 PF08777.11 CAM38840.1 - 0.00097 19.1 2.3 0.014 15.4 0.6 2.7 2 1 0 2 2 2 1 RNA binding motif PTS_2-RNA PF01885.16 CAM38840.1 - 0.017 15.1 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family AbiEi_2 PF09952.9 CAM38840.1 - 0.021 15.1 0.0 1.1 9.4 0.0 2.4 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system Biotin_lipoyl PF00364.22 CAM38841.1 - 8.8e-15 54.3 0.1 1.8e-14 53.3 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 CAM38841.1 - 0.03 14.7 0.7 0.098 13.0 0.1 2.2 2 1 0 2 2 2 0 e3 binding domain HlyD_3 PF13437.6 CAM38841.1 - 0.038 14.7 0.1 0.089 13.5 0.1 1.6 1 0 0 1 1 1 0 HlyD family secretion protein Acetyltransf_16 PF05301.11 CAM38842.1 - 0.019 14.7 0.1 0.022 14.5 0.1 1.0 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 V-SNARE_C PF12352.8 CAM38842.1 - 0.032 14.5 0.9 0.063 13.6 0.9 1.6 1 1 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus SNARE PF05739.19 CAM38842.1 - 0.044 13.8 1.0 0.13 12.3 0.5 2.0 2 0 0 2 2 2 0 SNARE domain TPR_MLP1_2 PF07926.12 CAM38843.1 - 0.036 14.1 1.6 0.09 12.8 1.6 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Exc PF07825.11 CAM38843.1 - 0.08 12.9 4.0 0.38 10.8 0.1 3.0 3 0 0 3 3 3 0 Excisionase-like protein Helicase_RecD PF05127.14 CAM38843.1 - 0.25 11.2 2.0 0.43 10.4 0.3 2.0 2 0 0 2 2 2 0 Helicase BssS PF13991.6 CAM38844.1 - 0.06 13.4 0.0 0.21 11.7 0.0 1.9 1 0 0 1 1 1 0 BssS protein family CTD_bind PF04818.13 CAM38844.1 - 0.12 13.3 0.0 0.74 10.7 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase II-binding domain. DAGK_prokar PF01219.19 CAM38844.1 - 0.18 11.6 0.2 0.18 11.6 0.2 2.2 2 0 0 2 2 2 0 Prokaryotic diacylglycerol kinase Noelin-1 PF12308.8 CAM38845.2 - 0.057 13.4 0.2 0.16 12.0 0.2 1.7 1 0 0 1 1 1 0 Neurogenesis glycoprotein DEAD PF00270.29 CAM38847.1 - 1.5e-15 57.4 0.0 1.7e-11 44.2 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CAM38847.1 - 1.1e-14 54.8 0.0 3.7e-14 53.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAM38847.1 - 0.00078 19.5 0.0 0.0022 18.0 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PA PF02225.22 CAM38847.1 - 0.035 14.1 0.5 0.13 12.3 0.5 2.0 1 0 0 1 1 1 0 PA domain SecA_DEAD PF07517.14 CAM38847.1 - 0.089 12.1 0.2 0.18 11.0 0.0 1.5 2 0 0 2 2 2 0 SecA DEAD-like domain IMS PF00817.20 CAM38848.2 - 1.5e-38 132.2 0.1 2.4e-38 131.5 0.1 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_HHH PF11798.8 CAM38848.2 - 0.0084 16.4 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif IMS PF00817.20 CAM38849.2 - 3.8e-48 163.3 0.1 5.7e-48 162.7 0.1 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 CAM38849.2 - 1e-05 26.2 0.0 2.4e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 CAM38849.2 - 0.0082 16.4 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif PGM_PMM_I PF02878.16 CAM38850.1 - 8.1e-31 106.6 0.0 1.5e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 CAM38850.1 - 2.5e-26 92.1 0.0 8.3e-26 90.4 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 CAM38850.1 - 9.5e-11 42.2 0.2 5.2e-10 39.9 0.2 2.3 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 CAM38850.1 - 2.6e-08 33.9 0.0 6.5e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain ParA PF10609.9 CAM38852.1 - 2.3e-85 286.0 0.0 2.9e-85 285.7 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CAM38852.1 - 9.8e-13 48.3 0.0 2.3e-11 43.8 0.0 2.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CAM38852.1 - 5.4e-07 29.7 0.5 1.2e-05 25.3 0.5 2.1 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 CAM38852.1 - 1.3e-06 27.9 0.0 2.1e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 CAM38852.1 - 0.00064 19.0 0.3 0.002 17.4 0.1 1.8 2 0 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.18 CAM38852.1 - 0.01 15.3 0.0 0.098 12.1 0.2 2.1 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MeaB PF03308.16 CAM38852.1 - 0.015 14.3 0.3 0.021 13.8 0.3 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 CAM38852.1 - 0.027 15.0 0.0 0.043 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 CAM38852.1 - 0.1 12.3 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein CBP_BcsQ PF06564.12 CAM38852.1 - 0.12 11.8 0.1 0.47 9.9 0.1 1.8 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ AAA_16 PF13191.6 CAM38852.1 - 0.14 12.5 0.1 0.24 11.8 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_26 PF13500.6 CAM38852.1 - 0.15 11.8 0.1 1.1 9.0 0.1 2.2 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CAM38852.1 - 0.19 12.1 0.2 0.38 11.2 0.2 1.5 1 0 0 1 1 1 0 RNA helicase Hist_deacetyl PF00850.19 CAM38854.1 - 1.8e-66 224.7 0.0 2.4e-66 224.3 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DSPc PF00782.20 CAM38856.1 - 7.9e-18 64.6 0.0 1.1e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain ABC_tran PF00005.27 CAM38857.1 - 1.3e-36 126.1 0.0 3e-17 63.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CAM38857.1 - 9.6e-11 42.0 3.8 0.0086 15.9 0.0 4.2 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CAM38857.1 - 2e-10 40.5 2.4 0.00095 18.7 0.3 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain RLI PF04068.15 CAM38857.1 - 5.1e-09 35.8 5.5 1.4e-08 34.4 5.5 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Fer4 PF00037.27 CAM38857.1 - 1.1e-07 31.3 2.2 1.1e-07 31.3 2.2 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_15 PF13175.6 CAM38857.1 - 3.5e-06 27.0 0.6 0.039 13.7 0.0 3.4 4 0 0 4 4 3 2 AAA ATPase domain AAA_16 PF13191.6 CAM38857.1 - 6.8e-06 26.6 0.0 0.012 16.0 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 CAM38857.1 - 5.7e-05 23.7 0.5 0.061 13.8 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CAM38857.1 - 8.6e-05 22.2 0.2 0.17 11.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain Fer4_6 PF12837.7 CAM38857.1 - 9.9e-05 22.3 15.3 0.00011 22.1 2.3 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_22 PF13401.6 CAM38857.1 - 0.00013 22.3 0.1 0.022 15.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain Fer4_21 PF14697.6 CAM38857.1 - 0.00017 21.6 14.9 0.00039 20.5 14.9 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Rad17 PF03215.15 CAM38857.1 - 0.00063 19.7 0.0 0.21 11.5 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA PF00004.29 CAM38857.1 - 0.0008 19.8 0.3 0.045 14.2 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 CAM38857.1 - 0.0008 19.3 0.0 0.21 11.5 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase Fer4_7 PF12838.7 CAM38857.1 - 0.0012 19.4 0.2 0.0012 19.4 0.2 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_28 PF13521.6 CAM38857.1 - 0.0015 18.8 0.0 3.4 7.9 0.0 2.8 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 CAM38857.1 - 0.0021 18.0 0.5 0.04 13.8 0.0 2.3 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 CAM38857.1 - 0.0023 18.3 0.0 0.67 10.4 0.0 3.0 3 0 0 3 3 2 1 RNA helicase Fer4_10 PF13237.6 CAM38857.1 - 0.0032 17.6 1.5 0.0032 17.6 1.5 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_30 PF13604.6 CAM38857.1 - 0.0033 17.2 0.0 2.3 7.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 CAM38857.1 - 0.0064 16.5 0.1 0.027 14.5 0.0 1.9 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 CAM38857.1 - 0.0081 15.8 0.4 0.93 9.1 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_5 PF07728.14 CAM38857.1 - 0.0096 15.9 1.0 0.81 9.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 CAM38857.1 - 0.012 15.3 0.1 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CAM38857.1 - 0.021 14.4 0.1 0.78 9.2 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 CAM38857.1 - 0.022 14.9 0.0 7.9 6.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CAM38857.1 - 0.023 15.2 0.0 4.8 7.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain Fer4_3 PF12798.7 CAM38857.1 - 0.031 15.2 4.0 0.031 15.2 4.0 2.7 2 0 0 2 2 1 0 4Fe-4S binding domain AAA_14 PF13173.6 CAM38857.1 - 0.041 13.9 0.0 1.3 9.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CAM38857.1 - 0.046 13.3 0.1 8.1 6.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CAM38857.1 - 0.06 13.7 0.2 1.8 8.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CAM38857.1 - 0.065 13.3 0.0 11 6.2 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_27 PF13514.6 CAM38857.1 - 0.081 12.5 0.1 1 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CAM38857.1 - 0.1 11.9 0.0 10 5.3 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin Fer4_9 PF13187.6 CAM38857.1 - 0.11 12.7 14.6 0.32 11.2 14.7 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain Leu_Phe_trans PF03588.14 CAM38859.1 - 0.0006 19.4 0.0 0.01 15.4 0.1 2.6 2 1 0 2 2 2 1 Leucyl/phenylalanyl-tRNA protein transferase Ribosomal_L36e PF01158.18 CAM38860.1 - 1.2e-28 99.2 2.1 1.4e-28 99.0 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e DUF543 PF04418.12 CAM38861.1 - 1.6e-13 50.4 0.6 1.8e-13 50.2 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) ParA PF10609.9 CAM38861.1 - 0.033 13.6 0.0 0.05 13.1 0.0 1.3 1 1 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase DLH PF01738.18 CAM38861.1 - 0.087 12.4 0.1 0.087 12.4 0.1 1.1 1 0 0 1 1 1 0 Dienelactone hydrolase family ATP-synt_C PF00137.21 CAM38862.1 - 1.3e-08 35.0 12.4 2.4e-08 34.2 12.4 1.4 1 0 0 1 1 1 1 ATP synthase subunit C PCI PF01399.27 CAM38864.1 - 8.2e-14 52.0 0.9 2.7e-13 50.3 0.1 2.4 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 CAM38864.1 - 5.1e-05 23.3 0.9 0.00027 21.0 0.4 2.4 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN5 C-terminal domain NPV_P10 PF05531.12 CAM38864.1 - 0.36 11.3 4.4 3.8 8.0 0.1 3.6 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF4404 PF14357.6 CAM38864.1 - 0.66 10.6 0.1 0.66 10.6 0.1 3.9 4 1 0 4 4 4 0 Domain of unknown function (DUF4404) Vps39_1 PF10366.9 CAM38864.1 - 2.2 8.6 9.7 16 5.9 2.2 3.5 2 1 1 3 3 3 0 Vacuolar sorting protein 39 domain 1 Ras PF00071.22 CAM38867.1 - 2.5e-45 154.0 0.0 3.1e-45 153.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAM38867.1 - 1.9e-33 115.2 0.0 2.7e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAM38867.1 - 3.2e-10 39.8 0.0 6.1e-10 38.8 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CAM38867.1 - 8.3e-06 25.5 0.0 3.1e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CAM38867.1 - 0.0002 20.8 0.0 0.00023 20.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CAM38867.1 - 0.00027 20.9 0.0 0.038 13.9 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CAM38867.1 - 0.0051 16.9 0.0 0.0081 16.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.6 CAM38867.1 - 0.013 15.1 0.0 3.8 7.0 0.0 2.7 2 1 0 2 2 2 0 AAA domain Not1 PF04054.15 CAM38869.1 - 6.1e-94 314.9 5.9 6.1e-94 314.9 5.9 2.0 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 CAM38869.1 - 9.2e-76 254.2 0.1 2.2e-75 252.9 0.1 1.7 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 CAM38869.1 - 8.4e-46 155.5 0.0 3.5e-45 153.5 0.0 2.1 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 CAM38869.1 - 1.4e-24 86.7 2.7 2.4e-24 85.9 0.4 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) tRNA-synt_1g PF09334.11 CAM38870.1 - 3.5e-91 305.9 0.4 1.3e-90 304.0 0.4 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 CAM38870.1 - 1.6e-17 63.0 1.3 6.5e-09 34.6 1.3 3.0 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 CAM38870.1 - 1.8e-07 30.8 0.1 0.0006 19.3 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain MKT1_C PF12246.8 CAM38871.1 - 1.8e-14 53.6 0.0 3.1e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 CAM38871.1 - 1.7e-11 44.3 0.0 3.4e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication ATG16 PF08614.11 CAM38873.2 - 0.00068 19.9 4.6 0.00068 19.9 4.6 20.7 5 3 13 21 21 21 6 Autophagy protein 16 (ATG16) Shugoshin_N PF07558.11 CAM38873.2 - 9.2 6.2 36.5 54 3.8 0.1 9.7 11 0 0 11 11 11 0 Shugoshin N-terminal coiled-coil region DUF4833 PF16117.5 CAM38874.1 - 3.7e-20 72.3 1.0 4.2e-10 39.8 0.1 3.1 2 1 0 2 2 2 2 Domain of unknown function (DUF4833) Peptidase_M24 PF00557.24 CAM38875.2 - 5.8e-41 140.5 0.1 8.2e-41 140.0 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 BAF1_ABF1 PF04684.13 CAM38875.2 - 0.12 11.4 3.6 0.22 10.6 3.6 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4833 PF16117.5 CAM38877.2 - 1.5e-07 31.5 0.0 2.3e-06 27.7 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4833) NinG PF05766.12 CAM38877.2 - 0.071 13.0 1.4 0.073 13.0 0.3 1.6 1 1 0 1 1 1 0 Bacteriophage Lambda NinG protein DUF2730 PF10805.8 CAM38878.2 - 0.066 13.3 0.4 0.31 11.2 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) MWFE PF15879.5 CAM38878.2 - 0.21 11.8 2.4 19 5.5 0.0 2.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit Pribosyltran PF00156.27 CAM38879.1 - 2.6e-21 75.8 0.0 3.4e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyltran PF00156.27 CAM38880.1 - 3.4e-17 62.4 0.0 4.4e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain KH_9 PF17904.1 CAM38880.1 - 0.11 12.8 0.0 0.47 10.8 0.0 2.0 3 0 0 3 3 3 0 FMRP KH0 domain Pkinase PF00069.25 CAM38881.1 - 8.3e-53 179.4 0.0 1.1e-36 126.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM38881.1 - 1.9e-26 92.9 0.0 1.2e-17 64.1 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CAM38881.1 - 3e-07 30.0 0.0 7.4e-07 28.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like BAG PF02179.16 CAM38882.1 - 0.00033 21.0 0.0 0.00059 20.2 0.0 1.4 1 0 0 1 1 1 1 BAG domain PUA PF01472.20 CAM38886.1 - 0.066 13.2 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 PUA domain HEAT PF02985.22 CAM38886.1 - 0.077 13.3 1.6 1.1 9.8 0.0 3.7 5 0 0 5 5 5 0 HEAT repeat HEAT_2 PF13646.6 CAM38886.1 - 0.095 13.1 1.8 0.2 12.1 0.9 2.1 2 0 0 2 2 2 0 HEAT repeats HEAT_EZ PF13513.6 CAM38886.1 - 0.69 10.5 3.9 1.9 9.1 0.3 3.1 2 0 0 2 2 2 0 HEAT-like repeat HEAT_2 PF13646.6 CAM38887.2 - 4.1e-10 39.9 0.9 0.0036 17.6 0.0 4.4 3 1 1 4 4 4 3 HEAT repeats DUF4042 PF13251.6 CAM38887.2 - 1.5e-08 34.5 0.2 6.3e-05 22.8 0.0 4.5 5 0 0 5 5 5 1 Domain of unknown function (DUF4042) HEAT PF02985.22 CAM38887.2 - 2.4e-06 27.3 2.0 2.7 8.5 0.0 6.4 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 CAM38887.2 - 0.004 17.6 0.4 0.004 17.6 0.4 6.2 6 1 1 7 7 7 2 HEAT-like repeat Cnd1 PF12717.7 CAM38887.2 - 0.14 12.2 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 ABC2_membrane PF01061.24 CAM38888.1 - 2e-12 47.0 17.4 2e-12 47.0 17.4 2.1 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 CAM38888.1 - 1.2e-08 35.5 0.0 2.2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter PDR_CDR PF06422.12 CAM38888.1 - 0.15 12.0 0.2 0.59 10.1 0.0 2.1 2 0 0 2 2 2 0 CDR ABC transporter Rab5ip PF07019.12 CAM38888.1 - 0.65 10.6 6.1 6.7 7.4 5.5 2.7 1 1 1 2 2 2 0 Rab5-interacting protein (Rab5ip) SR-25 PF10500.9 CAM38888.1 - 2.6 7.6 14.5 6.2 6.4 14.5 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ATP1G1_PLM_MAT8 PF02038.16 CAM38889.1 - 0.038 13.4 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family DUF4499 PF14934.6 CAM38890.1 - 6.4e-07 29.6 2.9 1e-06 28.9 2.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) MutS_V PF00488.21 CAM38891.1 - 1.4e-31 110.0 0.0 3.4e-31 108.7 0.0 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CAM38891.1 - 2.8e-18 66.8 0.1 3.6e-17 63.2 0.0 2.6 2 1 0 2 2 2 1 MutS domain III MutS_II PF05188.17 CAM38891.1 - 0.00064 20.0 0.1 0.0014 18.9 0.1 1.5 1 0 0 1 1 1 1 MutS domain II AAA_21 PF13304.6 CAM38891.1 - 0.0013 18.6 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CAM38891.1 - 0.0047 17.3 0.1 0.0047 17.3 0.1 3.1 4 0 0 4 4 4 1 AAA ATPase domain ABC_tran PF00005.27 CAM38891.1 - 0.05 14.1 0.2 0.12 12.9 0.2 1.6 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 CAM38891.1 - 0.054 14.0 0.4 0.054 14.0 0.4 1.6 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 CAM38891.1 - 0.055 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CAM38891.1 - 0.29 11.0 0.1 0.51 10.2 0.1 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF4148 PF13663.6 CAM38891.1 - 7.8 6.8 9.7 2 8.6 3.3 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) tRNA-synt_2 PF00152.20 CAM38893.1 - 1.3e-62 211.7 0.0 3.1e-62 210.5 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CAM38893.1 - 3.7e-07 30.0 0.0 7.1e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CAM38893.1 - 2.2e-06 27.4 0.1 0.0052 16.3 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Histone_H2A_C PF16211.5 CAM38894.1 - 9.1e-12 44.5 1.5 1.9e-11 43.5 1.5 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CAM38894.1 - 1.5e-06 28.6 0.1 2.5e-06 27.9 0.0 1.4 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 YihI PF04220.12 CAM38894.1 - 0.35 10.6 1.8 1.5 8.5 1.8 2.0 1 1 0 1 1 1 0 Der GTPase activator (YihI) Histone_H2A_C PF16211.5 CAM38895.1 - 9.5e-11 41.3 1.6 2e-10 40.2 1.6 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CAM38895.1 - 4e-07 30.5 0.4 6.2e-07 29.8 0.0 1.6 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 CAM38896.1 - 8.1e-12 44.7 1.5 1.9e-11 43.5 1.5 1.7 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CAM38896.1 - 3e-06 27.6 0.1 5e-06 26.9 0.0 1.4 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 PDCD2_C PF04194.13 CAM38898.2 - 7.4e-28 97.8 0.2 7.4e-28 97.8 0.2 2.2 2 1 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain Vps4_C PF09336.10 CAM38898.2 - 0.076 13.0 0.4 0.19 11.7 0.4 1.6 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain Bim_N PF06773.11 CAM38899.1 - 0.013 15.2 0.3 0.062 13.0 0.3 2.2 1 0 0 1 1 1 0 Bim protein N-terminus Methyltransf_2 PF00891.18 CAM38899.1 - 0.087 12.1 0.1 0.2 10.9 0.1 1.5 1 0 0 1 1 1 0 O-methyltransferase domain SET PF00856.28 CAM38900.2 - 0.18 12.2 0.0 0.42 11.0 0.0 1.9 1 1 0 1 1 1 0 SET domain Clathrin PF00637.20 CAM38901.1 - 4e-15 55.9 18.8 0.0059 16.5 0.0 10.7 8 3 3 12 12 12 3 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 CAM38901.1 - 7.2e-09 35.8 0.0 0.035 14.4 0.0 4.4 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CAM38901.1 - 2.3e-06 28.2 2.6 1.1 10.2 0.1 5.7 5 0 0 5 5 5 1 WD domain, G-beta repeat PPR PF01535.20 CAM38901.1 - 0.00021 21.3 7.9 0.64 10.4 0.1 7.8 6 1 1 7 7 7 1 PPR repeat ANAPC3 PF12895.7 CAM38901.1 - 0.00066 19.9 13.9 0.017 15.4 0.0 6.6 6 1 1 7 7 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CAM38901.1 - 0.00072 19.4 26.7 2.9 8.1 0.0 12.1 13 3 0 13 13 12 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 CAM38901.1 - 0.0012 18.0 10.0 0.12 11.4 0.2 5.4 4 2 2 6 6 6 2 Coatomer WD associated region TPR_11 PF13414.6 CAM38901.1 - 0.0044 16.7 8.8 10 5.9 0.1 6.2 5 0 0 5 5 5 0 TPR repeat TPR_1 PF00515.28 CAM38901.1 - 0.006 16.4 34.7 6.3 6.8 0.1 10.8 10 1 1 11 11 11 1 Tetratricopeptide repeat PPR_2 PF13041.6 CAM38901.1 - 0.021 15.0 2.7 1.1 9.5 0.1 5.0 5 0 0 5 5 5 0 PPR repeat family TPR_4 PF07721.14 CAM38901.1 - 0.034 14.8 13.6 1.1 10.0 0.0 8.5 10 1 1 11 11 8 0 Tetratricopeptide repeat PTAC PF06130.12 CAM38901.1 - 0.039 14.1 0.0 0.12 12.5 0.0 1.9 1 0 0 1 1 1 0 Phosphate propanoyltransferase TPR_17 PF13431.6 CAM38901.1 - 0.051 14.0 0.6 3.7 8.1 0.1 4.1 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 CAM38901.1 - 0.058 13.5 47.7 0.27 11.5 0.0 12.2 14 1 1 15 15 12 0 Tetratricopeptide repeat TPR_14 PF13428.6 CAM38901.1 - 0.12 13.3 46.3 12 7.1 0.1 15.3 12 6 2 15 15 14 0 Tetratricopeptide repeat DUF410 PF04190.13 CAM38901.1 - 0.2 11.4 8.3 0.35 10.6 0.0 4.1 4 1 1 5 5 5 0 Protein of unknown function (DUF410) C1_1 PF00130.22 CAM38901.1 - 0.27 11.1 1.7 0.6 10.0 1.7 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PPR_1 PF12854.7 CAM38901.1 - 0.38 10.5 2.3 0.54 10.0 0.3 2.5 2 0 0 2 2 2 0 PPR repeat TPR_12 PF13424.6 CAM38901.1 - 0.52 10.7 32.8 2.5 8.5 0.1 10.8 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_19 PF14559.6 CAM38901.1 - 1.2 9.7 19.1 1.6 9.3 0.0 7.9 7 2 2 9 9 8 0 Tetratricopeptide repeat TPR_8 PF13181.6 CAM38901.1 - 1.7 9.1 30.3 22 5.6 0.1 9.5 11 0 0 11 11 8 0 Tetratricopeptide repeat Pep3_Vps18 PF05131.14 CAM38901.1 - 4.2 7.2 6.9 61 3.4 0.1 4.9 6 0 0 6 6 5 0 Pep3/Vps18/deep orange family TetR_C_24 PF17932.1 CAM38903.2 - 0.28 11.4 1.9 0.67 10.2 0.2 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Tubulin PF00091.25 CAM38904.1 - 3.9e-62 210.0 0.0 5.3e-62 209.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CAM38904.1 - 5.8e-21 75.0 0.0 1e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 CAM38904.1 - 7.7e-06 25.3 0.0 1.2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin like Bombesin PF02044.17 CAM38904.1 - 0.17 12.0 1.2 0.36 11.0 1.2 1.5 1 0 0 1 1 1 0 Bombesin-like peptide Misat_Tub_SegII PF10644.9 CAM38904.1 - 0.18 12.1 0.0 0.33 11.3 0.0 1.4 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain Ax_dynein_light PF10211.9 CAM38905.1 - 1.6e-48 165.2 2.4 2.2e-48 164.7 2.4 1.2 1 0 0 1 1 1 1 Axonemal dynein light chain Borrelia_P83 PF05262.11 CAM38906.2 - 0.034 12.7 7.1 0.048 12.1 7.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Kinesin PF00225.23 CAM38907.1 - 6.5e-85 285.0 0.2 1.1e-84 284.2 0.2 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CAM38907.1 - 2.3e-13 50.4 0.0 6.2e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding Pox_A_type_inc PF04508.12 CAM38907.1 - 0.25 11.3 6.3 1.8 8.5 6.3 2.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Syntaxin-6_N PF09177.11 CAM38907.1 - 0.33 11.5 17.6 0.018 15.6 3.8 4.3 3 0 0 3 3 3 0 Syntaxin 6, N-terminal KIAA1430 PF13879.6 CAM38907.1 - 3.9 8.3 16.2 0.12 13.2 0.7 4.5 4 1 0 4 4 4 0 KIAA1430 homologue DUF3153 PF11353.8 CAM38907.1 - 6 6.4 8.2 0.62 9.6 1.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3153) Ribosomal_L6 PF00347.23 CAM38908.1 - 2.4e-25 89.0 2.4 3.5e-14 53.2 0.3 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Glyco_hydro_65C PF03633.15 CAM38908.1 - 0.048 13.6 0.2 5.8 6.9 0.1 3.0 3 1 0 3 3 3 0 Glycosyl hydrolase family 65, C-terminal domain Ribosom_S12_S23 PF00164.25 CAM38909.1 - 3.2e-48 162.1 0.4 3.2e-48 162.1 0.4 1.5 2 0 0 2 2 2 1 Ribosomal protein S12/S23 Ribosom_S12_S23 PF00164.25 CAM38910.1 - 3.2e-48 162.1 0.4 3.2e-48 162.1 0.4 1.5 2 0 0 2 2 2 1 Ribosomal protein S12/S23 Pkinase PF00069.25 CAM38911.1 - 3.9e-73 246.1 0.0 4.6e-73 245.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM38911.1 - 6.5e-34 117.4 0.0 8.3e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CAM38911.1 - 0.00094 19.2 0.7 0.014 15.3 0.4 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CAM38911.1 - 0.0018 17.6 0.0 0.038 13.3 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 CAM38911.1 - 0.0086 15.4 0.6 0.017 14.5 0.6 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CAM38911.1 - 0.086 11.8 0.0 10 4.9 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain IQ PF00612.27 CAM38913.1 - 3.4e-17 60.6 190.7 0.00019 20.9 0.0 23.2 25 1 1 26 26 26 14 IQ calmodulin-binding motif TPR_1 PF00515.28 CAM38913.1 - 9.3e-07 28.4 0.0 1.5 8.8 0.0 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 CAM38913.1 - 2.1e-05 24.7 1.3 2.1e-05 24.7 1.3 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 CAM38913.1 - 0.0085 15.9 0.1 0.0085 15.9 0.1 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 CAM38913.1 - 0.03 14.4 3.4 0.73 10.1 0.1 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 CAM38913.1 - 0.094 13.0 1.1 24 5.5 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat MqsA_antitoxin PF15731.5 CAM38913.1 - 0.93 9.6 7.4 0.52 10.4 0.3 3.6 2 1 1 3 3 3 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA SesA PF17107.5 CAM38913.1 - 3.8 7.7 10.2 5.3 7.2 0.4 3.9 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases WD40 PF00400.32 CAM38914.1 - 2.8e-14 53.2 7.9 0.06 14.2 0.0 6.8 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM38914.1 - 4.5e-05 23.7 0.0 11 6.4 0.0 4.3 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 CAM38914.1 - 0.0038 16.6 0.2 0.14 11.4 0.1 2.7 1 1 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 CAM38914.1 - 0.0077 14.9 0.1 0.02 13.6 0.0 1.6 2 0 0 2 2 2 1 Nucleoporin Nup120/160 RAB3GAP2_N PF14655.6 CAM38914.1 - 0.12 11.6 0.0 6.2 6.0 0.0 2.8 2 1 1 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Golgin_A5 PF09787.9 CAM38915.1 - 0.002 17.7 39.2 0.0024 17.4 0.0 4.1 2 1 1 4 4 4 2 Golgin subfamily A member 5 ATG16 PF08614.11 CAM38915.1 - 0.051 13.8 45.2 1.7 8.8 11.4 3.4 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) AAA PF00004.29 CAM38915.1 - 0.059 13.8 0.1 0.16 12.4 0.1 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) bZIP_1 PF00170.21 CAM38915.1 - 0.92 9.7 11.1 6.7 6.9 0.1 4.0 3 1 0 3 3 3 0 bZIP transcription factor SHE3 PF17078.5 CAM38915.1 - 1.5 8.5 19.0 1.4 8.6 1.5 2.8 2 1 1 3 3 3 0 SWI5-dependent HO expression protein 3 Filament PF00038.21 CAM38915.1 - 1.5 8.3 34.1 0.51 9.9 1.6 3.1 2 1 1 3 3 3 0 Intermediate filament protein CCDC144C PF14915.6 CAM38915.1 - 1.6 7.8 31.0 0.1 11.7 15.6 3.0 2 1 1 3 3 3 0 CCDC144C protein coiled-coil region CLZ PF16526.5 CAM38915.1 - 2.1 8.7 19.2 2.2 8.7 3.4 4.9 3 2 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TRAF_BIRC3_bd PF16673.5 CAM38915.1 - 5.2 6.9 6.1 28 4.6 0.7 3.0 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain EzrA PF06160.12 CAM38915.1 - 7.5 4.6 22.3 0.091 10.9 3.9 3.0 2 1 0 3 3 3 0 Septation ring formation regulator, EzrA LRR_8 PF13855.6 CAM38917.1 - 1.9e-27 94.8 10.1 1.4e-07 31.2 0.7 5.3 1 1 7 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 CAM38917.1 - 1.3e-17 63.5 12.0 0.00037 20.8 0.2 6.7 3 2 4 9 9 9 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CAM38917.1 - 1e-09 37.6 5.1 3.9 8.4 0.0 9.0 11 0 0 11 11 11 2 Leucine Rich Repeat LRR_6 PF13516.6 CAM38917.1 - 0.011 15.7 18.0 18 5.7 0.0 8.1 9 0 0 9 9 9 0 Leucine Rich repeat Ribosomal_L1 PF00687.21 CAM38918.1 - 1.6e-09 37.8 0.0 0.00016 21.5 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L1p/L10e family PIF1 PF05970.14 CAM38919.1 - 4.1e-33 115.0 0.1 1.5e-23 83.6 0.0 3.7 2 1 1 3 3 3 3 PIF1-like helicase AAA_30 PF13604.6 CAM38919.1 - 2.1e-14 53.7 0.5 1.4e-12 47.7 0.5 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CAM38919.1 - 2.2e-10 41.0 0.1 9e-10 39.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CAM38919.1 - 2.8e-06 27.3 0.1 0.38 10.5 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 CAM38919.1 - 2.5e-05 24.1 0.1 0.0007 19.4 0.1 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase Mg_chelatase PF01078.21 CAM38919.1 - 0.0014 18.0 0.3 0.0027 17.1 0.3 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI UvrD-helicase PF00580.21 CAM38919.1 - 0.0069 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 CAM38919.1 - 0.0077 16.0 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_32 PF13654.6 CAM38919.1 - 0.0084 14.9 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CAM38919.1 - 0.011 16.1 0.2 0.03 14.7 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 CAM38919.1 - 0.013 15.5 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 CAM38919.1 - 0.016 15.1 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_11 PF13086.6 CAM38919.1 - 0.034 13.9 1.8 0.23 11.2 0.0 2.6 3 0 0 3 3 3 0 AAA domain PhoH PF02562.16 CAM38919.1 - 0.052 13.0 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.9 CAM38919.1 - 0.075 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 CAM38919.1 - 0.095 12.2 0.1 0.98 8.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 CAM38919.1 - 0.15 11.8 0.0 0.63 9.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain Herpes_Helicase PF02689.14 CAM38919.1 - 0.26 9.2 0.1 0.68 7.8 0.0 1.6 2 0 0 2 2 2 0 Helicase ERM PF00769.19 CAM38920.1 - 0.022 14.6 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Ribosomal_L29 PF00831.23 CAM38920.1 - 0.15 12.1 2.5 0.19 11.7 0.2 2.2 2 0 0 2 2 2 0 Ribosomal L29 protein TK PF00265.18 CAM38921.1 - 1.7e-61 207.2 1.0 2.3e-61 206.7 1.0 1.2 1 0 0 1 1 1 1 Thymidine kinase AAA_14 PF13173.6 CAM38921.1 - 0.0013 18.7 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain TFIIB_C_1 PF18542.1 CAM38921.1 - 0.11 12.5 0.4 0.33 11.0 0.2 1.9 2 0 0 2 2 2 0 Transcription factor IIB C-terminal module 1 PKcGMP_CC PF16808.5 CAM38922.1 - 0.05 13.4 17.8 0.18 11.7 0.3 6.6 5 2 1 6 6 6 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Pox_A_type_inc PF04508.12 CAM38922.1 - 2.9 7.9 10.7 0.32 10.9 3.4 3.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat WD40 PF00400.32 CAM38924.1 - 1e-10 42.0 0.6 1.7e-06 28.7 0.1 5.0 6 0 0 6 6 6 2 WD domain, G-beta repeat CorA PF01544.18 CAM38924.1 - 0.038 13.3 0.1 0.038 13.3 0.1 3.9 4 0 0 4 4 4 0 CorA-like Mg2+ transporter protein Thiamine_BP PF01910.17 CAM38924.1 - 0.15 12.0 0.0 27 4.7 0.0 2.9 2 0 0 2 2 2 0 Thiamine-binding protein ComGG PF14173.6 CAM38924.1 - 0.18 12.2 0.1 0.18 12.2 0.1 2.3 3 0 0 3 3 3 0 ComG operon protein 7 ADK PF00406.22 CAM38925.1 - 1.6e-37 129.0 0.0 2.3e-37 128.4 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CAM38925.1 - 1.3e-17 64.5 0.1 2.8e-17 63.4 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CAM38925.1 - 1e-05 26.1 0.0 8.3e-05 23.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain ADK_lid PF05191.14 CAM38925.1 - 0.015 15.3 0.1 0.06 13.3 0.0 2.1 2 1 0 2 2 2 0 Adenylate kinase, active site lid AAA_33 PF13671.6 CAM38925.1 - 0.022 14.9 0.0 0.048 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain LRR_6 PF13516.6 CAM38926.1 - 1e-06 28.3 0.3 0.27 11.4 0.3 3.5 3 0 0 3 3 3 3 Leucine Rich repeat LRR_1 PF00560.33 CAM38926.1 - 0.18 12.5 1.1 38 5.4 0.0 3.2 3 0 0 3 3 3 0 Leucine Rich Repeat Serine_rich PF08824.10 CAM38927.1 - 0.0061 16.6 0.0 0.024 14.7 0.0 1.9 2 0 0 2 2 2 1 Serine rich protein interaction domain Mito_fiss_reg PF05308.11 CAM38927.1 - 0.059 13.5 0.2 0.11 12.5 0.2 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator SelR PF01641.18 CAM38928.1 - 0.024 14.7 0.1 2.6 8.1 0.0 2.6 2 0 0 2 2 2 0 SelR domain Synaptobrevin PF00957.21 CAM38929.1 - 9.4e-26 89.4 0.8 1.4e-25 88.9 0.8 1.2 1 0 0 1 1 1 1 Synaptobrevin NMO PF03060.15 CAM38930.1 - 1.8e-61 208.4 1.8 7e-40 137.4 1.6 2.0 1 1 1 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 CAM38930.1 - 2.2e-10 40.1 0.6 1.2e-08 34.4 0.6 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 CAM38930.1 - 1.1e-09 37.8 1.1 2e-09 37.0 1.1 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 CAM38930.1 - 1.7e-07 30.8 0.3 5.6e-07 29.1 0.2 1.7 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase ThiG PF05690.14 CAM38930.1 - 6.7e-05 22.3 0.4 0.0001 21.7 0.4 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 CAM38930.1 - 0.002 17.4 2.6 0.0038 16.4 2.6 1.5 1 1 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 CAM38930.1 - 0.023 14.2 0.1 0.041 13.3 0.1 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein NanE PF04131.14 CAM38930.1 - 0.034 13.3 0.1 0.064 12.4 0.1 1.4 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase zf-RING_2 PF13639.6 CAM38931.1 - 5.9e-09 36.1 3.8 4.4e-07 30.1 1.3 2.3 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.7 CAM38931.1 - 3.1e-08 33.8 1.0 5.3e-07 29.8 0.4 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CAM38931.1 - 7.1e-07 28.9 1.3 0.0073 16.0 0.2 2.4 2 0 0 2 2 2 2 RING-like zinc finger zf-C3HC4_2 PF13923.6 CAM38931.1 - 8.4e-07 28.7 4.5 1.4e-06 28.0 0.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CAM38931.1 - 5.6e-06 26.1 2.4 1.8e-05 24.5 0.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CAM38931.1 - 0.00015 21.8 0.4 0.00031 20.7 0.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 CAM38931.1 - 0.044 13.7 3.0 0.16 11.9 0.7 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CAM38931.1 - 0.11 12.6 7.6 0.3 11.1 1.5 3.0 2 1 1 3 3 3 0 RING-type zinc-finger zf-RING_5 PF14634.6 CAM38931.1 - 0.32 11.0 2.0 1.1 9.3 0.7 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_4 PF14570.6 CAM38931.1 - 1.5 8.7 3.7 0.35 10.7 0.5 1.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 CAM38931.1 - 2.7 8.2 5.3 0.41 10.8 1.0 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING RF-1 PF00472.20 CAM38932.1 - 5.2e-09 36.1 0.8 5.2e-09 36.1 0.8 4.0 4 1 1 5 5 5 1 RF-1 domain DUF4250 PF14056.6 CAM38932.1 - 0.081 12.9 0.1 0.081 12.9 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) DUF3818 PF12825.7 CAM38932.1 - 0.15 11.0 7.9 1.6 7.7 8.0 2.0 2 0 0 2 2 2 0 Domain of unknown function in PX-proteins (DUF3818) Laminin_II PF06009.12 CAM38932.1 - 0.31 11.0 10.3 1.4 9.0 9.2 2.6 1 1 0 1 1 1 0 Laminin Domain II PI_PP_I PF18363.1 CAM38932.1 - 0.46 10.7 2.0 15 5.8 0.0 2.8 2 1 1 3 3 3 0 Phosphoinositide phosphatase insertion domain GIT1_C PF12205.8 CAM38932.1 - 0.53 10.4 4.7 1.2 9.3 1.9 2.8 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term YabA PF06156.13 CAM38932.1 - 1.8 9.2 14.6 6.8 7.4 3.7 3.6 2 1 2 4 4 4 0 Initiation control protein YabA Prominin PF05478.11 CAM38932.1 - 1.9 6.3 5.6 3.6 5.4 5.6 1.4 1 0 0 1 1 1 0 Prominin LMBR1 PF04791.16 CAM38932.1 - 1.9 7.3 3.5 3.7 6.3 3.5 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF812 PF05667.11 CAM38932.1 - 6.4 5.5 21.5 0.62 8.9 16.6 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF812) DUF393 PF04134.12 CAM38935.1 - 0.0035 18.7 2.4 0.071 14.4 0.6 2.8 2 1 0 2 2 2 1 Protein of unknown function, DUF393 Phage_lysis PF03245.13 CAM38935.1 - 0.079 13.1 2.9 0.075 13.2 1.5 1.6 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein DUF971 PF06155.12 CAM38936.1 - 1.8e-15 57.3 0.0 3.8e-13 49.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF971) SMC_N PF02463.19 CAM38937.1 - 5.4e-70 235.3 6.2 5.7e-69 231.9 6.2 3.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CAM38937.1 - 3.6e-20 72.4 0.3 2.4e-19 69.8 0.0 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CAM38937.1 - 4.5e-12 46.4 1.4 3.2e-05 23.9 0.1 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CAM38937.1 - 1.7e-05 24.5 0.0 3.3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 CAM38937.1 - 2.2e-05 24.4 7.2 2.2e-05 24.4 7.2 4.0 3 1 0 3 3 3 1 AAA ATPase domain Spc7 PF08317.11 CAM38937.1 - 0.0004 19.4 13.0 0.0004 19.4 13.0 6.3 3 2 4 7 7 7 2 Spc7 kinetochore protein ABC_tran PF00005.27 CAM38937.1 - 0.11 13.0 0.0 0.11 13.0 0.0 5.0 4 2 0 4 4 4 0 ABC transporter DUF5398 PF17376.2 CAM38937.1 - 0.72 10.5 6.6 0.16 12.6 0.3 3.4 2 1 0 2 2 2 0 Family of unknown function (DUF5398) AAA_22 PF13401.6 CAM38937.1 - 1 9.6 0.0 1 9.6 0.0 4.8 5 2 1 6 6 6 0 AAA domain V-ATPase_H_N PF03224.14 CAM38938.1 - 2.7e-67 227.3 0.3 4.4e-67 226.6 0.3 1.3 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 CAM38938.1 - 1.8e-37 128.0 0.1 1.1e-36 125.4 0.0 2.2 2 0 0 2 2 2 1 V-ATPase subunit H RACo_linker PF17650.1 CAM38938.1 - 0.074 12.9 0.3 0.36 10.7 0.0 2.2 2 0 0 2 2 2 0 RACo linker region PB1 PF00564.24 CAM38939.1 - 4.4e-07 29.7 0.0 1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 PB1 domain MAM33 PF02330.16 CAM38942.1 - 0.035 14.1 0.3 0.072 13.0 0.3 1.4 1 0 0 1 1 1 0 Mitochondrial glycoprotein Mut7-C PF01927.16 CAM38945.1 - 0.012 15.8 0.0 1.2 9.3 0.0 2.7 2 0 0 2 2 2 0 Mut7-C RNAse domain HMG_box PF00505.19 CAM38946.1 - 2.3e-05 24.7 0.6 0.0021 18.4 0.2 3.1 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CAM38946.1 - 7.8e-05 23.2 2.1 0.021 15.4 0.2 3.0 3 0 0 3 3 3 2 HMG-box domain Sec8_exocyst PF04048.14 CAM38947.1 - 4.2e-11 42.9 0.2 1e-10 41.7 0.2 1.6 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Zw10 PF06248.13 CAM38947.1 - 0.00036 19.2 0.8 0.00066 18.4 0.8 1.3 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Vps54_N PF10475.9 CAM38947.1 - 0.0026 17.1 0.4 0.0056 16.0 0.4 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Mpp10 PF04006.12 CAM38947.1 - 0.36 9.2 14.2 0.73 8.2 14.2 1.4 1 0 0 1 1 1 0 Mpp10 protein Cwf_Cwc_15 PF04889.12 CAM38947.1 - 0.39 10.4 11.6 1.1 9.0 11.6 1.7 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 CAM38947.1 - 0.46 9.8 15.5 0.1 12.0 11.4 1.8 2 0 0 2 2 2 0 BUD22 Nop14 PF04147.12 CAM38947.1 - 0.69 8.0 17.3 1.2 7.3 17.3 1.2 1 0 0 1 1 1 0 Nop14-like family Ribosomal_S17_N PF16205.5 CAM38948.1 - 2.4e-27 95.1 0.5 2.4e-27 95.1 0.5 1.6 2 0 0 2 2 2 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 CAM38948.1 - 3.5e-22 78.3 0.5 3.5e-22 78.3 0.5 1.8 2 0 0 2 2 2 1 Ribosomal protein S17 DEAD PF00270.29 CAM38950.1 - 6.7e-37 126.9 0.3 8.7e-36 123.3 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAM38950.1 - 7.5e-26 90.7 0.8 2.7e-25 88.9 0.2 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAM38950.1 - 2.7e-09 37.3 0.0 5.4e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 CAM38950.1 - 0.0037 16.6 2.1 0.027 13.8 0.0 3.1 2 1 1 4 4 4 1 U3-containing 90S pre-ribosomal complex subunit DUF4844 PF16133.5 CAM38950.1 - 0.061 13.9 0.6 0.061 13.9 0.6 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4844) LETM1 PF07766.13 CAM38951.1 - 0.00053 19.4 0.1 0.0011 18.4 0.1 1.5 1 0 0 1 1 1 1 LETM1-like protein Tn7_Tnp_TnsA_N PF08722.11 CAM38951.1 - 0.037 14.2 0.1 0.089 13.0 0.1 1.6 1 0 0 1 1 1 0 TnsA endonuclease N terminal GST_C_6 PF17171.4 CAM38952.1 - 5.6e-08 32.5 0.0 1.6e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CAM38952.1 - 0.00013 21.9 0.5 0.00031 20.7 0.0 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Cas_Cas2CT1978 PF09707.10 CAM38952.1 - 0.16 12.0 0.2 0.56 10.3 0.1 2.0 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) COG6 PF06419.11 CAM38953.1 - 0.17 10.1 0.0 0.23 9.6 0.0 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 GMC_oxred_N PF00732.19 CAM38954.1 - 2.5e-12 46.8 0.0 3.4e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CAM38954.1 - 3.5e-11 43.8 0.0 1.7e-10 41.6 0.0 2.1 2 1 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 CAM38954.1 - 0.00057 19.2 0.1 0.094 11.9 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CAM38954.1 - 0.0017 18.5 1.4 0.003 17.7 0.3 2.1 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CAM38954.1 - 0.0025 16.9 0.0 0.013 14.6 0.0 2.1 3 0 0 3 3 3 1 Lycopene cyclase protein HI0933_like PF03486.14 CAM38954.1 - 0.0029 16.4 0.2 0.0041 15.9 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 CAM38954.1 - 0.0095 15.1 0.1 0.016 14.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CAM38954.1 - 0.014 15.0 0.1 0.12 11.9 0.1 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 CAM38954.1 - 0.035 13.3 0.5 0.035 13.3 0.5 2.0 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.6 CAM38954.1 - 0.1 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 CAM38955.1 - 1.7e-63 214.5 0.0 3e-63 213.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM38955.1 - 5.4e-44 150.4 0.0 1e-43 149.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM38955.1 - 1.2e-05 24.8 0.0 1.2e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 CAM38955.1 - 0.0033 17.1 0.7 0.0096 15.5 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 CAM38955.1 - 0.2 10.4 0.0 0.2 10.4 0.0 2.8 3 1 0 3 3 3 0 Fungal protein kinase MIP-T3_C PF17749.1 CAM38956.1 - 6.1e-51 172.4 7.3 6.1e-51 172.4 7.3 3.6 3 1 1 4 4 4 1 Microtubule-binding protein MIP-T3 C-terminal region MIP-T3 PF10243.9 CAM38956.1 - 1.7e-49 166.5 1.3 5.5e-49 164.9 0.2 2.3 2 1 0 2 2 2 1 Microtubule-binding protein MIP-T3 CH-like domain TFIIF_alpha PF05793.12 CAM38956.1 - 0.4 9.2 27.7 0.59 8.7 27.7 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) UPF0242 PF06785.11 CAM38956.1 - 1.6 8.8 19.8 0.044 13.9 2.7 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus peroxidase PF00141.23 CAM38958.1 - 4.3e-11 42.9 0.0 4.3e-10 39.7 0.0 2.1 1 1 1 2 2 2 1 Peroxidase DUF4094 PF13334.6 CAM38958.1 - 0.009 16.4 0.2 0.18 12.2 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4094) ANAPC4_WD40 PF12894.7 CAM38959.1 - 0.087 13.1 0.2 0.73 10.2 0.0 2.6 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CAM38959.1 - 0.28 12.1 5.8 2.7 9.0 0.1 4.5 5 0 0 5 5 5 0 WD domain, G-beta repeat E1_dh PF00676.20 CAM38961.1 - 5.6e-79 265.2 0.0 8.1e-79 264.7 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Cyt-b5 PF00173.28 CAM38962.1 - 2.9e-05 24.1 0.0 0.00012 22.1 0.0 2.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PRMT5 PF05185.16 CAM38963.2 - 3.4e-39 134.4 0.0 5.9e-39 133.7 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 CAM38963.2 - 8.5e-24 84.4 0.0 1.3e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain MIT PF04212.18 CAM38965.1 - 0.00011 22.2 2.9 0.0017 18.4 0.1 2.6 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 CAM38965.1 - 0.0011 18.9 6.7 0.075 13.2 0.5 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CAM38965.1 - 0.0025 17.9 4.5 14 6.2 0.7 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 CAM38965.1 - 0.0055 17.0 8.8 4.6 7.6 0.4 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat DNA_pol_lambd_f PF10391.9 CAM38965.1 - 0.058 13.2 0.1 7.3 6.5 0.0 2.6 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda TPR_10 PF13374.6 CAM38965.1 - 0.22 11.5 4.3 49 4.0 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 CAM38965.1 - 0.26 11.2 8.7 0.6 10.0 1.8 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CAM38965.1 - 0.36 11.5 6.5 34 5.3 0.8 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat MFS_1 PF07690.16 CAM38966.1 - 9e-05 21.5 26.3 9e-05 21.5 26.3 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.13 CAM38966.1 - 0.0019 17.7 20.9 0.0019 17.7 20.9 2.9 2 1 0 2 2 2 1 Nodulin-like HemY_N PF07219.13 CAM38966.1 - 6.9 6.9 10.2 0.57 10.4 0.1 3.4 3 1 2 5 5 5 0 HemY protein N-terminus F-box-like PF12937.7 CAM38967.1 - 7.2e-07 29.0 1.0 2.1e-06 27.5 1.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CAM38967.1 - 0.00034 20.4 2.0 0.0014 18.5 2.0 2.1 1 0 0 1 1 1 1 F-box domain DUF5079 PF16882.5 CAM38967.1 - 1.8 8.4 13.6 0.1 12.5 1.9 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF5079) SfsA PF03749.13 CAM38968.1 - 0.022 14.6 0.5 0.62 10.0 0.1 2.5 1 1 1 2 2 2 0 Sugar fermentation stimulation protein RE domain NDUFB10 PF10249.9 CAM38968.1 - 0.22 12.0 3.2 0.26 11.8 0.0 2.3 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase subunit 10 DUF3782 PF12644.7 CAM38968.1 - 0.24 11.6 3.5 12 6.1 0.1 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF3782) WXG100 PF06013.12 CAM38968.1 - 0.26 11.5 1.8 6.4 7.1 0.1 3.0 3 0 0 3 3 3 0 Proteins of 100 residues with WXG SKA2 PF16740.5 CAM38968.1 - 0.28 11.0 7.6 0.17 11.7 0.7 3.0 3 1 0 3 3 3 0 Spindle and kinetochore-associated protein 2 BLOC1_2 PF10046.9 CAM38968.1 - 0.58 10.5 4.8 10 6.5 0.2 3.3 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 KELK PF15796.5 CAM38968.1 - 1 9.9 9.0 4.9 7.7 0.7 3.0 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PEP-utilisers_N PF05524.13 CAM38968.1 - 3.6 7.8 5.5 3.9 7.7 1.1 3.0 1 1 2 3 3 3 0 PEP-utilising enzyme, N-terminal TMF_TATA_bd PF12325.8 CAM38968.1 - 5.6 7.2 8.7 0.65 10.2 1.4 2.6 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding zf-Sec23_Sec24 PF04810.15 CAM38969.1 - 0.033 14.3 3.4 0.059 13.4 0.1 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger HpaB PF03241.13 CAM38969.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase C terminal DUF2407 PF10302.9 CAM38970.1 - 0.01 16.4 0.1 0.022 15.3 0.0 1.8 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain PPR_2 PF13041.6 CAM38971.2 - 1.9e-08 34.4 0.2 4.8e-08 33.1 0.1 1.8 2 0 0 2 2 2 1 PPR repeat family PPR_3 PF13812.6 CAM38971.2 - 2.7e-05 24.2 0.0 4.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR PF01535.20 CAM38971.2 - 0.00027 21.0 1.7 0.00046 20.3 0.1 2.3 3 0 0 3 3 3 1 PPR repeat PPR_long PF17177.4 CAM38971.2 - 0.0088 15.4 0.1 0.013 14.9 0.1 1.2 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 CAM38971.2 - 0.15 11.8 0.0 0.52 10.1 0.0 1.9 2 0 0 2 2 2 0 PPR repeat CKS PF01111.19 CAM38971.2 - 0.17 12.2 0.4 0.74 10.1 0.1 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase regulatory subunit EF-hand_1 PF00036.32 CAM38972.1 - 7.2e-24 81.5 9.4 1e-06 27.8 0.2 4.5 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 CAM38972.1 - 3.7e-22 78.5 3.7 7.2e-13 48.8 1.1 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 CAM38972.1 - 1.3e-19 68.4 8.3 6.7e-05 22.5 0.3 4.8 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 CAM38972.1 - 1.1e-16 59.4 13.1 5e-07 28.9 0.2 4.9 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 CAM38972.1 - 6.4e-12 45.1 7.0 0.00024 20.9 1.1 4.1 3 2 1 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.7 CAM38972.1 - 1.6e-06 28.0 1.7 0.27 11.2 0.2 3.4 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CAM38972.1 - 3.4e-06 27.3 0.0 0.014 15.7 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 CAM38972.1 - 7.9e-06 26.0 0.7 0.00024 21.2 0.6 2.6 2 1 0 2 2 2 1 Dockerin type I domain DUF3349 PF11829.8 CAM38972.1 - 0.062 14.1 0.1 18 6.2 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3349) DUF1425 PF07233.12 CAM38972.1 - 0.09 12.7 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1425) DUF5310 PF17237.2 CAM38973.1 - 0.0028 17.5 0.0 0.0077 16.1 0.0 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5310) TetR_C_31 PF17940.1 CAM38973.1 - 0.033 14.4 0.1 0.078 13.2 0.1 1.7 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Pkinase PF00069.25 CAM38974.1 - 8e-41 140.1 0.0 1e-40 139.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM38974.1 - 4e-10 39.4 0.0 7.2e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CAM38974.1 - 0.051 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family 5_3_exonuc_N PF02739.16 CAM38975.1 - 1.5e-26 93.2 0.1 2.3e-26 92.6 0.1 1.3 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 CAM38975.1 - 2.9e-19 69.5 0.0 5.5e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold EspB_PE PF18625.1 CAM38975.1 - 0.055 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 ESX-1 secreted protein B PE domain zf-MYND PF01753.18 CAM38977.1 - 0.0034 17.4 19.8 0.0073 16.4 19.8 1.6 1 0 0 1 1 1 1 MYND finger DKCLD PF08068.12 CAM38978.1 - 5.6e-24 84.0 0.1 8e-24 83.5 0.1 1.2 1 0 0 1 1 1 1 DKCLD (NUC011) domain TruB_N PF01509.18 CAM38978.1 - 7.7e-15 55.6 0.3 9.4e-15 55.3 0.3 1.1 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUF PF00806.19 CAM38979.1 - 8.2e-49 160.6 6.5 1e-05 24.9 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 CAM38979.1 - 0.0018 18.6 0.5 8.9 6.7 0.0 3.6 2 1 1 3 3 3 3 CPL (NUC119) domain HrpB1_HrpK PF09613.10 CAM38979.1 - 0.027 14.1 0.2 1.3 8.7 0.1 3.0 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) T_hemolysin PF12261.8 CAM38979.1 - 0.15 11.8 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Thermostable hemolysin MCU PF04678.13 CAM38980.1 - 1.1e-32 113.6 1.2 1.6e-32 113.0 1.2 1.3 1 0 0 1 1 1 1 Mitochondrial calcium uniporter DUF2339 PF10101.9 CAM38980.1 - 0.031 12.9 0.4 0.038 12.6 0.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) SYS1 PF09801.9 CAM38980.1 - 0.1 12.7 2.0 0.16 12.1 2.0 1.3 1 0 0 1 1 1 0 Integral membrane protein S linking to the trans Golgi network SLATT_1 PF18181.1 CAM38980.1 - 0.15 12.0 1.9 0.6 10.1 1.9 1.9 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 Proteasome PF00227.26 CAM38981.1 - 8.1e-64 214.6 0.0 1.2e-63 214.1 0.0 1.2 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CAM38981.1 - 4.1e-09 36.0 0.6 2.2e-08 33.6 0.1 2.2 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature YadA_head PF05658.14 CAM38981.1 - 0.32 11.5 6.8 0.95 9.9 1.2 2.3 2 0 0 2 2 2 0 Head domain of trimeric autotransporter adhesin DUF4874 PF16173.5 CAM38982.1 - 0.18 11.5 0.4 0.25 11.0 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4874) Ribosomal_L32e PF01655.18 CAM38983.2 - 5.7e-38 129.6 0.1 6.7e-38 129.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 PEHE PF15275.6 CAM38984.1 - 0.0026 18.4 6.4 0.0026 18.4 6.4 2.1 1 1 1 2 2 2 1 PEHE domain Wbp11 PF09429.10 CAM38984.1 - 0.16 12.4 17.3 0.054 13.9 10.1 2.4 2 0 0 2 2 2 0 WW domain binding protein 11 DUF2868 PF11067.8 CAM38984.1 - 0.26 10.7 4.2 0.18 11.3 2.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2868) ESCRT-II PF05871.12 CAM38984.1 - 1.4 9.1 6.3 5.2 7.3 6.3 1.9 1 1 0 1 1 1 0 ESCRT-II complex subunit TipAS PF07739.13 CAM38984.1 - 3.1 8.4 8.2 0.38 11.3 3.3 1.9 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain PAP_assoc PF03828.19 CAM38985.1 - 3.2e-05 24.0 0.3 0.00021 21.4 0.1 2.3 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CAM38985.1 - 0.027 14.7 0.0 0.08 13.2 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain SET PF00856.28 CAM38986.1 - 9e-06 26.2 0.6 0.00047 20.6 0.6 2.4 1 1 0 1 1 1 1 SET domain PHD PF00628.29 CAM38986.1 - 0.052 13.4 11.3 0.18 11.7 11.3 2.0 1 1 0 1 1 1 0 PHD-finger FYVE PF01363.21 CAM38986.1 - 0.73 10.0 9.7 2.5 8.3 9.7 1.9 1 0 0 1 1 1 0 FYVE zinc finger DKCLD PF08068.12 CAM38987.1 - 1.5e-31 108.3 0.1 2.4e-30 104.4 0.1 2.5 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 CAM38987.1 - 4.9e-22 78.9 1.9 2.3e-15 57.2 0.4 3.3 1 1 1 2 2 2 2 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 CAM38987.1 - 2.4e-20 72.5 0.3 4.3e-20 71.6 0.3 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 CAM38987.1 - 2.8e-20 72.0 1.0 5.5e-20 71.1 1.0 1.5 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 CAM38987.1 - 0.0021 18.3 0.0 0.0081 16.4 0.0 2.0 2 0 0 2 2 2 1 UPF0113 PUA domain zf-C3HC4 PF00097.25 CAM38989.1 - 1.7e-09 37.4 7.6 3.3e-09 36.4 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CAM38989.1 - 3.6e-09 36.5 3.9 3.6e-09 36.5 3.9 2.6 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CAM38989.1 - 1.7e-08 34.2 10.0 2.5e-08 33.6 1.8 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CAM38989.1 - 7.1e-08 32.5 5.9 1.9e-07 31.1 5.9 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CAM38989.1 - 2.7e-07 30.4 7.3 7e-07 29.1 7.3 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CAM38989.1 - 8.7e-07 28.7 7.2 1.6e-06 27.8 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CAM38989.1 - 3.1e-06 27.4 8.2 6e-06 26.5 8.2 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CAM38989.1 - 0.00061 19.6 6.2 0.0013 18.6 6.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CAM38989.1 - 0.0068 16.7 5.5 0.018 15.3 5.5 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain Croc_4 PF17691.1 CAM38989.1 - 0.06 13.4 1.0 0.18 11.8 1.0 1.8 1 0 0 1 1 1 0 Contingent replication of cDNA 4 zf-ANAPC11 PF12861.7 CAM38989.1 - 0.12 12.4 2.4 0.26 11.3 2.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 CAM38989.1 - 0.53 10.1 5.2 2.6 7.9 6.0 1.8 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 CAM38989.1 - 1.2 8.9 5.3 3.4 7.5 5.3 1.8 1 1 0 1 1 1 0 RING-like zinc finger TolA_bind_tri PF16331.5 CAM38990.1 - 0.0075 16.3 0.1 0.022 14.8 0.1 1.7 1 0 0 1 1 1 1 TolA binding protein trimerisation DUF885 PF05960.11 CAM38990.1 - 0.013 15.1 1.7 0.026 14.2 1.7 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) PKcGMP_CC PF16808.5 CAM38990.1 - 0.042 13.7 0.3 0.11 12.4 0.3 1.6 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Kinesin_assoc PF16183.5 CAM38990.1 - 0.14 12.3 0.4 0.3 11.2 0.4 1.5 1 1 0 1 1 1 0 Kinesin-associated DUF4407 PF14362.6 CAM38990.1 - 0.48 9.7 3.0 0.75 9.1 2.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) MGDG_synth PF06925.11 CAM38991.1 - 0.12 12.5 0.3 0.14 12.3 0.3 1.1 1 0 0 1 1 1 0 Monogalactosyldiacylglycerol (MGDG) synthase DUF4040 PF13244.6 CAM38992.1 - 0.53 10.5 9.2 0.11 12.7 1.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4040) Pkinase PF00069.25 CAM38994.1 - 8.8e-48 163.0 0.0 5e-47 160.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM38994.1 - 4.2e-34 118.0 0.0 6.7e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM38994.1 - 2.9e-05 23.5 0.0 5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CAM38994.1 - 0.0023 16.8 0.0 0.0037 16.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 CAM38994.1 - 0.012 15.3 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 CAM38994.1 - 0.026 14.4 0.1 0.093 12.6 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Tubulin PF00091.25 CAM38995.1 - 1.9e-67 227.3 0.0 3.2e-67 226.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CAM38995.1 - 1.5e-41 141.5 0.1 2.3e-41 140.9 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CAM38995.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CAM38995.1 - 0.013 15.2 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain DHHC PF01529.20 CAM38998.1 - 9.8e-32 109.9 3.4 9.8e-32 109.9 3.4 1.8 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF588 PF04535.12 CAM38998.1 - 0.06 13.1 1.5 0.14 12.0 1.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF588) Herpes_UL73 PF03554.13 CAM38998.1 - 6.2 6.9 9.5 0.12 12.4 0.9 2.3 2 0 0 2 2 2 0 UL73 viral envelope glycoprotein Glycos_transf_2 PF00535.26 CAM39000.1 - 2.4e-08 34.0 0.0 4.3e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 FR47 PF08445.10 CAM39001.2 - 1.6e-06 28.0 0.0 2.4e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 CAM39001.2 - 7.2e-06 26.0 0.1 9.4e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CAM39001.2 - 2.4e-05 24.5 0.0 3.1e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF2431 PF10354.9 CAM39002.2 - 4.1e-24 85.7 0.0 7.4e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) zf-C2H2_jaz PF12171.8 CAM39002.2 - 2.1e-05 24.6 0.8 0.0015 18.8 0.1 3.2 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 CAM39002.2 - 2.6e-05 24.4 9.3 0.075 13.5 0.5 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CAM39002.2 - 5.8e-05 23.6 8.1 3.3 8.8 0.1 4.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 CAM39002.2 - 0.00093 19.5 2.1 0.003 17.9 0.1 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CAM39002.2 - 0.25 11.7 3.1 1.5 9.2 0.8 2.5 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 CAM39002.2 - 0.36 10.9 0.1 0.36 10.9 0.1 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger YabA PF06156.13 CAM39003.2 - 0.0076 16.9 0.4 0.0076 16.9 0.4 3.5 2 1 1 3 3 3 1 Initiation control protein YabA TSC22 PF01166.18 CAM39003.2 - 0.056 13.8 5.0 0.18 12.1 1.9 3.1 1 1 1 2 2 2 0 TSC-22/dip/bun family DUF4874 PF16173.5 CAM39003.2 - 0.092 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4874) CEP44 PF15007.6 CAM39004.1 - 0.00092 19.4 0.0 0.0012 19.0 0.0 1.1 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 Got1 PF04178.12 CAM39005.1 - 3.3e-26 91.9 17.6 4.3e-26 91.6 17.6 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family AzlD PF05437.12 CAM39005.1 - 0.19 11.9 9.4 2.2 8.5 10.3 2.0 1 1 1 2 2 2 0 Branched-chain amino acid transport protein (AzlD) DUF3270 PF11674.8 CAM39005.1 - 1.4 9.2 5.1 0.85 9.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) RRM_1 PF00076.22 CAM39007.1 - 2.6e-63 209.7 0.5 1e-19 70.1 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CAM39007.1 - 2.3e-18 66.1 0.1 5.2e-18 65.0 0.1 1.6 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_occluded PF16842.5 CAM39007.1 - 1.7e-06 27.8 0.0 0.0013 18.5 0.0 3.8 4 0 0 4 4 4 1 Occluded RNA-recognition motif RRM_7 PF16367.5 CAM39007.1 - 7.4e-06 26.0 0.1 0.13 12.4 0.0 4.4 4 2 0 4 4 4 2 RNA recognition motif PHM7_cyt PF14703.6 CAM39007.1 - 0.00025 21.3 0.2 7.8 6.7 0.0 4.6 3 2 2 5 5 5 2 Cytosolic domain of 10TM putative phosphate transporter OB_RNB PF08206.11 CAM39007.1 - 0.045 13.4 0.5 0.88 9.3 0.1 2.6 2 0 0 2 2 2 0 Ribonuclease B OB domain Mlh1_C PF16413.5 CAM39007.1 - 0.056 12.8 0.0 0.094 12.1 0.0 1.3 1 0 0 1 1 1 0 DNA mismatch repair protein Mlh1 C-terminus RPAP1_N PF08621.10 CAM39008.1 - 0.0011 18.6 4.6 0.12 12.1 0.7 2.2 2 0 0 2 2 2 2 RPAP1-like, N-terminal Laminin_II PF06009.12 CAM39008.1 - 0.0061 16.6 0.6 0.0079 16.2 0.6 1.3 1 0 0 1 1 1 1 Laminin Domain II DUF1640 PF07798.11 CAM39008.1 - 0.011 15.8 0.0 0.012 15.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) APG17 PF04108.12 CAM39008.1 - 0.018 14.1 0.7 0.022 13.9 0.7 1.0 1 0 0 1 1 1 0 Autophagy protein Apg17 TSNAXIP1_N PF15739.5 CAM39008.1 - 0.036 14.5 0.2 0.042 14.2 0.2 1.1 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus Sec20 PF03908.13 CAM39008.1 - 0.049 13.5 0.8 0.53 10.2 0.8 2.0 1 1 0 1 1 1 0 Sec20 DUF2207 PF09972.9 CAM39008.1 - 0.07 11.9 0.0 0.081 11.7 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) BAR_3_WASP_bdg PF10456.9 CAM39008.1 - 0.074 12.5 0.1 0.084 12.3 0.1 1.1 1 0 0 1 1 1 0 WASP-binding domain of Sorting nexin protein Spidroin_N PF16763.5 CAM39008.1 - 0.11 12.5 0.9 0.14 12.2 0.9 1.1 1 0 0 1 1 1 0 Major ampullate spidroin 1, spider silk protein 1, N-term DUF364 PF04016.12 CAM39009.1 - 0.018 14.6 0.0 0.021 14.4 0.0 1.0 1 0 0 1 1 1 0 Putative heavy-metal chelation CrgA PF06781.12 CAM39009.1 - 0.04 14.0 0.3 0.046 13.8 0.3 1.1 1 0 0 1 1 1 0 Cell division protein CrgA DUF4044 PF13253.6 CAM39009.1 - 0.24 11.0 2.7 0.41 10.2 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) ETF PF01012.21 CAM39011.1 - 7.1e-43 146.6 2.6 8.7e-43 146.3 2.6 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain PIG-L PF02585.17 CAM39011.1 - 0.019 15.6 0.0 0.032 14.9 0.0 1.4 1 0 0 1 1 1 0 GlcNAc-PI de-N-acetylase GTP_EFTU PF00009.27 CAM39012.1 - 2.6e-50 170.7 0.1 3.9e-50 170.1 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CAM39012.1 - 5.9e-14 51.9 0.0 1.4e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus Septin PF00735.18 CAM39012.1 - 1.4e-05 24.5 0.1 2.4e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CAM39012.1 - 1.8e-05 24.8 0.1 3.8e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 CAM39012.1 - 0.0045 17.1 0.0 0.016 15.3 0.0 2.0 1 0 0 1 1 1 1 Elongation Factor G, domain II RnfC_N PF13375.6 CAM39012.1 - 0.12 12.3 0.1 0.78 9.7 0.0 2.3 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain RNA_pol_Rpb6 PF01192.22 CAM39013.1 - 5.2e-09 35.9 0.0 1e-08 35.0 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb6 DivIC PF04977.15 CAM39015.1 - 0.14 11.9 8.1 0.16 11.7 0.3 3.1 2 1 1 3 3 3 0 Septum formation initiator CENP-H PF05837.12 CAM39015.1 - 8.4 6.9 8.1 7.5 7.0 0.7 2.5 2 1 0 2 2 2 0 Centromere protein H (CENP-H) Lactamase_B_6 PF16661.5 CAM39016.2 - 3.2e-19 69.1 0.0 5e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 CAM39016.2 - 1.5e-14 54.5 3.7 1.8e-14 54.3 0.4 2.5 2 1 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Lactamase_B PF00753.27 CAM39016.2 - 0.0039 17.2 0.1 0.0098 15.9 0.1 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Beta-Casp PF10996.8 CAM39016.2 - 0.042 14.2 0.0 0.14 12.5 0.0 1.8 2 0 0 2 2 2 0 Beta-Casp domain Peptidase_C12 PF01088.21 CAM39018.2 - 4.9e-54 183.3 0.0 5.6e-54 183.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 WD40_3 PF15911.5 CAM39019.1 - 1.8e-14 53.5 0.0 5.6e-13 48.7 0.0 2.9 2 0 0 2 2 2 1 WD domain, G-beta repeat Clathrin PF00637.20 CAM39019.1 - 3.2e-07 30.3 2.2 0.00062 19.7 0.2 3.9 4 0 0 4 4 4 2 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 CAM39019.1 - 4e-07 30.2 0.0 0.08 13.3 0.0 4.3 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_14 PF13428.6 CAM39019.1 - 0.0027 18.4 7.9 19 6.4 0.0 6.0 5 1 2 7 7 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CAM39019.1 - 0.0087 16.3 5.5 0.033 14.4 0.9 4.1 3 2 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CAM39019.1 - 0.018 15.0 6.3 7.5 6.8 0.1 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 CAM39019.1 - 0.019 15.5 7.8 0.11 13.0 0.0 5.0 4 2 1 5 5 5 0 Tetratricopeptide repeat KNOX2 PF03791.13 CAM39019.1 - 0.029 13.9 0.0 0.078 12.5 0.0 1.7 1 0 0 1 1 1 0 KNOX2 domain WD40 PF00400.32 CAM39019.1 - 0.061 14.2 6.9 7.5 7.6 0.2 5.7 5 0 0 5 5 5 0 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 CAM39019.1 - 0.13 11.2 2.2 2.3 7.2 0.3 3.6 3 1 1 4 4 4 0 Coatomer WD associated region Mad3_BUB1_I PF08311.12 CAM39019.1 - 0.66 10.0 2.1 17 5.4 0.1 3.3 3 0 0 3 3 3 0 Mad3/BUB1 homology region 1 zf-ribbon_3 PF13248.6 CAM39019.1 - 0.97 8.9 5.6 3.8 7.1 2.6 2.7 2 0 0 2 2 2 0 zinc-ribbon domain TPR_12 PF13424.6 CAM39019.1 - 1.3 9.3 13.5 48 4.4 0.2 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Mito_carr PF00153.27 CAM39020.1 - 1.2e-59 198.2 0.2 2.9e-20 72.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SyrA PF11089.8 CAM39021.1 - 0.035 14.2 1.9 0.067 13.3 1.9 1.4 1 0 0 1 1 1 0 Exopolysaccharide production repressor GRP PF07172.11 CAM39021.1 - 2 9.2 20.5 0.22 12.2 14.7 2.2 2 0 0 2 2 2 0 Glycine rich protein family Spt5_N PF11942.8 CAM39021.1 - 3.1 8.8 8.1 2.1 9.4 0.3 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DSPc PF00782.20 CAM39022.1 - 2.1e-15 56.7 0.1 3.4e-15 56.0 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CAM39022.1 - 2.8e-05 24.3 0.1 6.2e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 CAM39022.1 - 0.0055 16.3 0.2 0.0077 15.8 0.2 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 CAM39022.1 - 0.014 15.1 0.1 0.025 14.3 0.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 CAM39022.1 - 0.032 14.2 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Bud13 PF09736.9 CAM39023.1 - 1.6e-06 28.6 0.1 2.4e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor of RES complex DUF3135 PF11333.8 CAM39024.2 - 0.087 13.1 5.8 4.9 7.5 1.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) FH2 PF02181.23 CAM39024.2 - 1.2 8.1 11.3 1.2 8.2 4.3 2.3 2 0 0 2 2 2 0 Formin Homology 2 Domain Dynein_light PF01221.18 CAM39025.1 - 7.6e-33 112.7 0.3 8.4e-33 112.6 0.3 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 N_NLPC_P60 PF12912.7 CAM39025.1 - 0.13 12.6 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 NLPC_P60 stabilising domain, N term Phage_GP20 PF06810.11 CAM39026.2 - 0.013 15.3 1.9 0.013 15.3 1.9 5.5 5 1 0 5 5 5 0 Phage minor structural protein GP20 DUF3450 PF11932.8 CAM39027.1 - 0.01 15.1 0.1 0.01 15.1 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) MutS_III PF05192.18 CAM39027.1 - 0.018 15.2 1.3 8.1 6.6 5.1 2.3 2 1 0 2 2 2 0 MutS domain III zf-C4H2 PF10146.9 CAM39027.1 - 0.072 13.4 1.7 0.72 10.1 0.1 2.6 2 0 0 2 2 2 0 Zinc finger-containing protein IPT PF01745.16 CAM39027.1 - 0.092 12.1 2.8 4.5 6.6 0.7 2.5 2 0 0 2 2 2 0 Isopentenyl transferase DUF150 PF02576.17 CAM39027.1 - 0.11 12.9 3.5 3 8.3 1.2 2.6 2 0 0 2 2 2 0 RimP N-terminal domain Macoilin PF09726.9 CAM39027.1 - 0.19 10.3 8.2 0.35 9.4 7.5 1.7 2 0 0 2 2 2 0 Macoilin family V_ATPase_I PF01496.19 CAM39027.1 - 2.2 6.1 9.9 0.49 8.2 5.4 2.0 3 0 0 3 3 3 0 V-type ATPase 116kDa subunit family Yuri_gagarin PF15934.5 CAM39027.1 - 2.3 8.0 12.6 0.54 10.1 8.5 1.9 2 0 0 2 2 2 0 Yuri gagarin GIT_CC PF16559.5 CAM39027.1 - 4.5 7.2 7.9 1.5 8.7 4.5 1.9 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor TMPIT PF07851.13 CAM39027.1 - 5.5 6.1 6.7 26 3.9 4.3 2.3 2 0 0 2 2 2 0 TMPIT-like protein RRM_1 PF00076.22 CAM39028.1 - 3.6e-05 23.5 0.1 0.002 17.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Diphthami_syn_2 PF01902.17 CAM39029.1 - 1.5e-32 112.9 0.1 2.3e-30 105.7 0.1 2.9 1 1 0 1 1 1 1 Diphthamide synthase BRCT_2 PF16589.5 CAM39030.1 - 8.4e-08 32.5 0.0 0.00035 20.9 0.0 2.5 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain B9-C2 PF07162.11 CAM39031.1 - 2.2e-11 44.2 0.0 2.2e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein SPRY PF00622.28 CAM39032.1 - 4e-06 27.0 0.0 7.2e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 SPRY domain SUI1 PF01253.22 CAM39035.1 - 1.2e-18 67.3 0.0 2.4e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 WD40 PF00400.32 CAM39037.1 - 1.7e-37 126.7 17.3 2.1e-08 34.7 1.0 8.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Utp13 PF08625.11 CAM39037.1 - 1.8e-32 112.2 1.8 3.2e-32 111.4 1.8 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 CAM39037.1 - 2.3e-14 53.4 6.8 5.5e-06 26.6 0.0 6.2 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CAM39037.1 - 2.2e-06 26.9 2.0 1.7 7.6 0.1 4.6 3 2 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein UTP15_C PF09384.10 CAM39037.1 - 0.0029 17.3 1.8 0.0067 16.1 1.8 1.6 1 0 0 1 1 1 1 UTP15 C terminal Nup160 PF11715.8 CAM39037.1 - 0.0032 16.2 5.8 1.8 7.1 0.2 4.1 2 1 2 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 CAM39037.1 - 0.0037 16.7 0.3 1.2 8.3 0.0 3.5 3 2 0 4 4 4 1 WD40-like domain Utp12 PF04003.12 CAM39037.1 - 0.01 16.1 1.5 0.023 15.0 1.5 1.7 1 0 0 1 1 1 0 Dip2/Utp12 Family MMS1_N PF10433.9 CAM39037.1 - 0.038 12.6 0.0 0.29 9.7 0.0 2.4 3 0 0 3 3 3 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term PHTB1_N PF14727.6 CAM39037.1 - 0.05 13.0 1.8 0.37 10.1 0.1 2.4 3 0 0 3 3 3 0 PTHB1 N-terminus TFIIB PF00382.19 CAM39038.2 - 1.1e-23 83.1 0.1 1.2e-11 44.5 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 CAM39038.2 - 0.13 11.8 0.1 0.32 10.6 0.1 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding MMR_HSR1 PF01926.23 CAM39039.1 - 1.6e-13 50.7 0.0 2.8e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CAM39039.1 - 1.5e-07 31.1 0.0 8.4e-06 25.4 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CAM39039.1 - 4.3e-06 26.7 0.0 5.1e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 CAM39039.1 - 0.00038 20.6 0.5 0.17 11.9 0.2 2.4 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 CAM39039.1 - 0.00053 19.4 0.0 0.00091 18.6 0.0 1.4 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 CAM39039.1 - 0.00068 19.2 0.0 0.064 12.8 0.0 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CAM39039.1 - 0.0099 15.3 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP-synt_F6 PF05511.11 CAM39040.1 - 0.18 12.3 0.1 0.43 11.0 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 Kringle PF00051.18 CAM39041.1 - 1.7e-15 57.0 0.4 3.7e-15 56.0 0.4 1.6 1 0 0 1 1 1 1 Kringle domain CHB_HEX_C_1 PF13290.6 CAM39041.1 - 0.00056 19.9 3.4 0.001 19.0 0.1 3.0 3 0 0 3 3 3 1 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.6 CAM39041.1 - 0.0083 16.3 0.0 0.033 14.3 0.0 2.1 1 0 0 1 1 1 1 Fn3 associated RRM_1 PF00076.22 CAM39043.1 - 2.6e-21 75.2 0.0 3.4e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CAM39043.1 - 2.8e-06 26.9 0.0 4.9e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CAM39043.1 - 0.0025 17.6 0.0 0.0049 16.7 0.0 1.5 1 1 0 1 1 1 1 Occluded RNA-recognition motif Nrf1_DNA-bind PF10491.9 CAM39043.1 - 0.11 12.2 0.3 0.19 11.4 0.1 1.5 2 0 0 2 2 2 0 NLS-binding and DNA-binding and dimerisation domains of Nrf1 RRM_1 PF00076.22 CAM39044.1 - 2.6e-21 75.2 0.0 3.5e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CAM39044.1 - 3.8e-06 26.5 0.0 6.8e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CAM39044.1 - 0.0026 17.6 0.0 0.0049 16.7 0.0 1.5 1 1 0 1 1 1 1 Occluded RNA-recognition motif RRM_1 PF00076.22 CAM39046.1 - 2.4e-19 68.9 0.5 4.2e-18 64.9 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CAM39046.1 - 0.0099 15.5 0.0 0.024 14.2 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_membrane PF00664.23 CAM39047.1 - 3.8e-51 174.4 3.5 5.3e-51 173.9 3.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CAM39047.1 - 1.1e-33 116.6 0.0 2e-33 115.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CAM39047.1 - 3.2e-05 23.5 0.1 0.054 12.9 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CAM39047.1 - 0.00037 20.9 0.9 0.0053 17.2 0.8 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 CAM39047.1 - 0.00057 20.3 0.2 0.0083 16.6 0.2 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 CAM39047.1 - 0.011 15.5 0.2 0.19 11.5 0.0 2.6 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_5 PF07728.14 CAM39047.1 - 0.016 15.2 0.2 0.27 11.2 0.1 2.6 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CAM39047.1 - 0.021 15.1 1.5 0.23 11.8 0.5 2.7 2 1 1 3 3 3 0 AAA domain ABC_ATPase PF09818.9 CAM39047.1 - 0.026 13.3 0.1 0.049 12.4 0.1 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_29 PF13555.6 CAM39047.1 - 0.029 14.1 0.0 0.069 12.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 CAM39047.1 - 0.034 13.8 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 CAM39047.1 - 0.045 13.0 0.0 0.12 11.6 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin RsgA_GTPase PF03193.16 CAM39047.1 - 0.064 13.2 0.0 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase DUF87 PF01935.17 CAM39047.1 - 0.12 12.4 0.1 0.34 11.0 0.0 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain Rab3-GTPase_cat PF13890.6 CAM39048.1 - 7.3e-41 139.5 0.1 1.5e-40 138.5 0.1 1.5 1 0 0 1 1 1 1 Rab3 GTPase-activating protein catalytic subunit ENTH PF01417.20 CAM39049.1 - 1.4e-26 93.0 0.0 2.1e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 ENTH domain CCDC50_N PF15295.6 CAM39049.1 - 0.043 14.0 8.4 0.11 12.7 8.4 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus Alpha_kinase PF02816.18 CAM39050.1 - 1e-54 185.5 0.0 1.6e-53 181.6 0.0 2.1 2 0 0 2 2 2 1 Alpha-kinase family Peptidase_S9 PF00326.21 CAM39053.1 - 0.096 12.1 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family SCAMP PF04144.13 CAM39054.2 - 4.6e-36 124.7 12.9 5.4e-36 124.5 12.9 1.0 1 0 0 1 1 1 1 SCAMP family Yip1 PF04893.17 CAM39054.2 - 3.4 7.4 14.4 6.1 6.5 14.3 1.4 1 1 0 1 1 1 0 Yip1 domain Sugarporin_N PF11471.8 CAM39054.2 - 4.2 7.4 7.3 0.59 10.1 0.7 2.8 2 1 1 3 3 3 0 Maltoporin periplasmic N-terminal extension eIF-5a PF01287.20 CAM39057.1 - 2.2e-25 88.5 0.0 3e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 CAM39057.1 - 0.00017 21.5 0.0 0.00042 20.3 0.0 1.7 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain eIF-5a PF01287.20 CAM39058.1 - 2.2e-25 88.5 0.0 3e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 CAM39058.1 - 0.00017 21.5 0.0 0.00042 20.3 0.0 1.7 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain eIF-5a PF01287.20 CAM39059.1 - 2.2e-25 88.5 0.0 3e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 CAM39059.1 - 0.00017 21.5 0.0 0.00042 20.3 0.0 1.7 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain eIF-5a PF01287.20 CAM39060.1 - 2.2e-25 88.5 0.0 3e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 CAM39060.1 - 0.00017 21.5 0.0 0.00042 20.3 0.0 1.7 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain SNF2_N PF00176.23 CAM39061.1 - 1.6e-54 184.9 0.1 3.2e-28 98.4 0.0 3.4 2 1 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 CAM39061.1 - 1.6e-17 63.8 0.4 1.6e-16 60.6 0.0 3.0 4 0 0 4 4 4 1 Helicase conserved C-terminal domain zf-PARP PF00645.18 CAM39061.1 - 1e-13 51.9 0.4 3.1e-13 50.4 0.4 1.9 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-RING_2 PF13639.6 CAM39061.1 - 3.4e-05 24.1 3.6 3.4e-05 24.1 3.6 2.9 3 0 0 3 3 2 1 Ring finger domain zf-RING_11 PF17123.5 CAM39061.1 - 0.00013 21.6 2.2 0.00013 21.6 2.2 2.5 2 0 0 2 2 2 1 RING-like zinc finger ERCC3_RAD25_C PF16203.5 CAM39061.1 - 0.00028 20.2 0.0 0.00059 19.1 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase zf-C3HC4 PF00097.25 CAM39061.1 - 0.00076 19.3 3.1 0.00076 19.3 3.1 3.3 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 CAM39061.1 - 0.0014 18.7 0.0 0.32 11.0 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 CAM39061.1 - 0.0018 18.1 2.6 0.0018 18.1 2.6 2.7 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CAM39061.1 - 0.048 13.9 2.6 0.22 11.8 2.6 2.2 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CAM39061.1 - 0.15 12.1 1.4 0.5 10.4 1.4 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CAM39061.1 - 0.68 10.0 5.6 3 7.9 5.6 2.3 1 0 0 1 1 1 0 RING-type zinc-finger PP2C PF00481.21 CAM39062.2 - 3e-50 171.3 0.0 3.7e-50 171.0 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CAM39062.2 - 0.00094 18.9 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CAM39062.2 - 0.0042 17.0 0.0 0.027 14.4 0.0 2.0 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) TIP39 PF14980.6 CAM39062.2 - 0.025 14.4 0.0 0.077 12.9 0.0 1.8 1 0 0 1 1 1 0 TIP39 peptide Ank_2 PF12796.7 CAM39066.2 - 6e-08 33.2 0.6 0.019 15.5 0.0 4.5 2 2 4 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CAM39066.2 - 1e-05 26.0 0.8 0.41 11.3 0.0 4.2 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CAM39066.2 - 0.0015 18.9 0.9 0.2 12.3 0.0 4.1 3 0 0 3 3 3 1 Ankyrin repeat PSCyt3 PF07627.11 CAM39066.2 - 0.1 12.9 0.0 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1588) zf-DNL PF05180.12 CAM39067.1 - 8.1e-28 96.2 0.1 1.6e-27 95.2 0.1 1.5 1 0 0 1 1 1 1 DNL zinc finger zf-RING_4 PF14570.6 CAM39067.1 - 0.066 13.0 0.5 0.15 11.9 0.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Cyclin_N PF00134.23 CAM39068.1 - 5.4e-07 29.4 0.6 0.00045 20.0 0.0 3.2 3 0 0 3 3 3 2 Cyclin, N-terminal domain TFIIB_C_1 PF18542.1 CAM39068.1 - 0.094 12.8 2.3 0.36 10.9 2.3 2.0 1 0 0 1 1 1 0 Transcription factor IIB C-terminal module 1 Prefoldin_2 PF01920.20 CAM39069.1 - 3.2e-11 43.1 1.4 3.9e-11 42.8 1.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 CAM39069.1 - 9.5e-05 22.3 1.9 0.018 14.9 0.4 2.1 2 0 0 2 2 2 2 Prefoldin subunit XhlA PF10779.9 CAM39069.1 - 0.0031 17.7 2.8 0.2 11.9 0.1 2.1 2 0 0 2 2 2 2 Haemolysin XhlA DUF4140 PF13600.6 CAM39069.1 - 0.012 16.0 0.9 5.4 7.5 0.0 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF5082 PF16888.5 CAM39069.1 - 0.018 15.3 0.3 0.75 10.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) FapA PF03961.13 CAM39069.1 - 0.022 13.4 0.4 0.027 13.1 0.4 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Tropomyosin_1 PF12718.7 CAM39069.1 - 0.037 14.2 3.4 3.9 7.6 1.9 2.1 2 0 0 2 2 2 0 Tropomyosin like PEP-utilisers_N PF05524.13 CAM39069.1 - 0.083 13.1 0.3 0.18 12.0 0.2 1.6 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal TPR_MLP1_2 PF07926.12 CAM39069.1 - 0.089 12.9 5.3 0.2 11.7 1.5 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DivIC PF04977.15 CAM39069.1 - 0.21 11.4 4.0 8.4 6.3 1.8 2.2 2 0 0 2 2 2 0 Septum formation initiator THOC7 PF05615.13 CAM39069.1 - 0.22 11.8 3.1 0.45 10.8 3.1 1.6 1 1 0 1 1 1 0 Tho complex subunit 7 Spc24 PF08286.11 CAM39069.1 - 0.26 11.5 2.7 3.1 8.1 2.8 2.1 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DUF4164 PF13747.6 CAM39069.1 - 2.1 8.7 7.8 37 4.7 7.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) DAP10 PF07213.11 CAM39070.1 - 0.15 12.0 0.8 0.44 10.5 0.8 1.8 1 0 0 1 1 1 0 DAP10 membrane protein PH PF00169.29 CAM39071.1 - 0.0036 17.8 0.1 0.13 12.7 0.0 2.8 2 1 0 2 2 2 1 PH domain Cortex-I_coil PF09304.10 CAM39072.2 - 0.44 10.8 5.8 0.86 9.9 5.8 1.4 1 0 0 1 1 1 0 Cortexillin I, coiled coil Kdo PF06293.14 CAM39074.1 - 6.9e-07 28.8 0.3 0.00011 21.6 0.2 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CAM39074.1 - 0.00024 20.7 0.0 0.32 10.6 0.0 2.2 1 1 1 2 2 2 2 RIO1 family Pkinase PF00069.25 CAM39074.1 - 0.019 14.4 0.0 0.051 12.9 0.0 1.8 1 1 0 1 1 1 0 Protein kinase domain LRR_8 PF13855.6 CAM39075.1 - 1.7e-17 62.9 6.7 7.2e-11 41.7 1.3 3.6 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 CAM39075.1 - 4.3e-10 39.7 4.0 5.9e-05 23.4 0.2 4.0 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CAM39075.1 - 0.0026 17.3 0.0 0.0055 16.2 0.0 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 CAM39075.1 - 0.073 13.7 6.7 0.14 12.8 0.1 4.3 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 CAM39075.1 - 1.2 9.4 3.9 73 3.8 0.1 3.8 3 0 0 3 3 3 0 Leucine Rich repeat PKcGMP_CC PF16808.5 CAM39075.1 - 4.4 7.2 9.2 0.27 11.1 0.2 3.4 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Ribosomal_L23 PF00276.20 CAM39076.1 - 1.5e-06 28.5 0.1 2.5e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 FixS PF03597.15 CAM39077.1 - 1.2 8.9 4.7 0.81 9.4 0.4 2.6 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type Pro_isomerase PF00160.21 CAM39078.2 - 4.3e-45 153.8 0.0 4.9e-45 153.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SLBP_RNA_bind PF15247.6 CAM39079.1 - 4.2e-18 65.2 0.2 4.2e-18 65.2 0.2 2.5 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain Ank_4 PF13637.6 CAM39080.1 - 4.6e-17 62.2 1.0 3.3e-07 30.7 0.2 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CAM39080.1 - 7.1e-15 55.4 0.0 1.7e-08 34.9 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CAM39080.1 - 2.5e-14 52.0 2.4 7.1e-05 22.9 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 CAM39080.1 - 3e-13 49.7 3.5 6.2e-07 29.6 0.1 3.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 CAM39080.1 - 4.8e-13 48.9 4.0 0.00015 22.1 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat zf-RVT PF13966.6 CAM39080.1 - 0.07 13.8 0.1 0.36 11.6 0.0 2.1 1 1 1 2 2 2 0 zinc-binding in reverse transcriptase PUB PF09409.10 CAM39082.1 - 0.0013 18.6 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 PUB domain Tubulin PF00091.25 CAM39083.1 - 2.2e-67 227.1 0.0 3.3e-67 226.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CAM39083.1 - 3.1e-44 150.2 0.2 5.9e-44 149.3 0.2 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CAM39083.1 - 1.1e-05 25.8 0.0 3.3e-05 24.2 0.0 1.9 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 CAM39083.1 - 0.003 16.8 0.0 0.005 16.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin like Tubulin_3 PF14881.6 CAM39083.1 - 0.04 13.6 0.0 0.098 12.3 0.0 1.6 2 0 0 2 2 2 0 Tubulin domain EF-hand_7 PF13499.6 CAM39084.2 - 1.4e-05 25.4 0.0 0.088 13.3 0.0 4.1 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_6 PF13405.6 CAM39084.2 - 0.0085 15.9 0.0 5.7 7.1 0.0 3.3 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 CAM39084.2 - 0.24 11.3 0.0 0.68 9.8 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair AAA_6 PF12774.7 CAM39085.2 - 2.1e-144 480.5 1.8 2.1e-143 477.2 0.0 3.0 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 CAM39085.2 - 2.3e-142 475.6 11.4 2.3e-142 475.6 11.4 2.9 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 CAM39085.2 - 9e-116 387.2 4.3 9e-116 387.2 4.3 3.7 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 CAM39085.2 - 1.7e-87 293.0 0.0 4.9e-87 291.5 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CAM39085.2 - 1.1e-77 261.3 0.1 6.7e-77 258.7 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 CAM39085.2 - 9.4e-76 253.8 7.3 9.4e-76 253.8 7.3 2.6 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 CAM39085.2 - 2.7e-52 176.9 8.7 4.3e-50 169.7 0.1 5.0 6 0 0 6 6 5 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CAM39085.2 - 5e-45 153.2 0.1 8e-44 149.3 0.1 2.7 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CAM39085.2 - 1.1e-37 128.8 2.2 2.9e-36 124.1 0.1 3.5 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 CAM39085.2 - 2.2e-37 128.9 8.5 2.2e-37 128.9 8.5 1.7 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 CAM39085.2 - 5.3e-20 71.8 0.2 3.6e-19 69.1 0.2 2.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CAM39085.2 - 1.3e-15 57.6 0.0 0.0016 18.5 0.0 5.6 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 CAM39085.2 - 3.3e-11 43.3 0.1 6.8e-10 39.1 0.1 3.1 1 1 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 CAM39085.2 - 1.8e-07 31.6 1.4 0.038 14.4 0.0 5.6 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CAM39085.2 - 6.9e-06 26.5 0.7 5.1 7.4 0.0 6.3 6 0 0 6 6 6 1 AAA ATPase domain AAA_18 PF13238.6 CAM39085.2 - 0.0063 17.1 0.0 0.24 12.0 0.0 3.7 3 0 0 3 3 3 1 AAA domain PET PF06297.14 CAM39085.2 - 0.054 13.8 0.1 0.23 11.8 0.1 2.2 1 0 0 1 1 1 0 PET Domain SNF5 PF04855.12 CAM39085.2 - 0.07 12.9 4.2 3.4 7.4 0.1 3.4 3 0 0 3 3 3 0 SNF5 / SMARCB1 / INI1 AAA_22 PF13401.6 CAM39085.2 - 0.28 11.5 8.3 24 5.2 0.0 5.6 6 0 0 6 6 6 0 AAA domain Complex1_LYR PF05347.15 CAM39086.1 - 0.00029 20.8 0.0 0.00063 19.7 0.0 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) 2OG-FeII_Oxy PF03171.20 CAM39088.1 - 8.3e-15 55.1 0.0 1.8e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 CAM39088.1 - 0.0079 16.9 0.0 1.4 9.7 0.0 2.5 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal PrlF_antitoxin PF15937.5 CAM39088.1 - 0.059 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 prlF antitoxin for toxin YhaV_toxin SecE PF00584.20 CAM39089.1 - 1.4e-12 47.3 0.2 1.7e-12 47.1 0.2 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex NAD_binding_2 PF03446.15 CAM39090.1 - 1.8e-29 102.9 0.0 3e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 CAM39090.1 - 8.3e-13 48.7 0.2 2.1e-11 44.1 0.1 2.5 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 CAM39090.1 - 7.1e-05 22.9 0.3 0.0044 17.1 0.1 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 CAM39090.1 - 0.0065 17.0 0.1 0.051 14.2 0.0 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 CAM39090.1 - 0.0084 16.9 0.0 1.1 10.1 0.0 2.9 2 1 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold 3HCDH_N PF02737.18 CAM39090.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RcsD_ABL PF16359.5 CAM39090.1 - 0.18 11.9 0.0 0.41 10.8 0.0 1.5 1 0 0 1 1 1 0 RcsD-ABL domain BBP1_C PF15272.6 CAM39092.1 - 0.049 13.4 0.5 0.11 12.3 0.5 1.6 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Frataxin_Cyay PF01491.16 CAM39093.1 - 5.7e-28 97.1 0.0 8.3e-28 96.6 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain Inhibitor_I42 PF09394.10 CAM39094.1 - 0.00016 22.0 11.8 13 6.3 0.9 7.5 2 1 2 5 5 5 1 Chagasin family peptidase inhibitor I42 FAS_meander PF17951.1 CAM39094.1 - 0.0065 16.3 14.3 0.81 9.5 0.6 4.2 2 1 2 4 4 4 3 Fatty acid synthase meander beta sheet domain DUF5550 PF17704.1 CAM39094.1 - 0.064 13.4 0.3 0.18 11.9 0.3 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5550) LPD29 PF18847.1 CAM39094.1 - 0.13 13.2 0.9 2.4e+02 2.7 0.0 4.6 1 1 2 3 3 3 0 Large polyvalent protein associated domain 29 DUF916 PF06030.12 CAM39094.1 - 0.71 10.0 7.5 5.3 7.1 0.6 3.8 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF916) Lge1 PF11488.8 CAM39094.1 - 0.76 10.0 16.9 12 6.1 0.8 4.8 3 1 0 4 4 4 0 Transcriptional regulatory protein LGE1 MALT1_Ig PF18703.1 CAM39094.1 - 0.97 9.4 10.1 2.6 8.1 1.7 3.4 1 1 2 3 3 3 0 MALT1 Ig-like domain AATF-Che1 PF13339.6 CAM39095.1 - 0.0049 17.6 1.8 0.0049 17.6 1.8 2.8 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor CorA PF01544.18 CAM39095.1 - 0.84 8.9 3.3 0.56 9.5 0.4 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein GAS PF13851.6 CAM39095.1 - 6.6 6.0 19.9 0.67 9.3 0.1 3.3 4 0 0 4 4 4 0 Growth-arrest specific micro-tubule binding RRM_1 PF00076.22 CAM39096.1 - 0.0014 18.4 0.1 0.0029 17.4 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2652 PF10851.8 CAM39096.1 - 0.021 14.9 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2652) CorA PF01544.18 CAM39097.1 - 3e-19 69.4 0.0 1.1e-18 67.6 0.0 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DnaJ_C PF01556.18 CAM39098.1 - 2.2e-33 115.4 0.0 2.9e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CAM39098.1 - 2.4e-15 56.4 0.1 3.8e-15 55.8 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CAM39098.1 - 1.9e-13 50.6 12.8 3.1e-13 49.9 12.8 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CAM39098.1 - 8.9e-08 32.0 7.6 0.00093 19.1 1.0 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein T6SS_TssF PF05947.12 CAM39098.1 - 0.018 13.6 0.0 0.025 13.1 0.0 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssF HypA PF01155.19 CAM39098.1 - 0.092 12.8 10.7 1.4 9.0 2.1 2.3 1 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 CAM39098.1 - 0.12 12.1 0.3 0.12 12.1 0.3 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 DZR PF12773.7 CAM39098.1 - 0.32 11.1 11.3 0.52 10.4 1.6 2.2 1 1 2 3 3 3 0 Double zinc ribbon PHF5 PF03660.14 CAM39098.1 - 0.46 10.7 5.3 1 9.6 5.3 1.6 1 1 0 1 1 1 0 PHF5-like protein Lar_restr_allev PF14354.6 CAM39098.1 - 0.46 10.9 9.0 22 5.5 0.5 3.5 2 1 1 3 3 3 0 Restriction alleviation protein Lar zinc_ribbon_9 PF14369.6 CAM39098.1 - 0.52 10.6 12.8 3.9 7.8 0.3 3.5 2 2 1 3 3 3 0 zinc-ribbon zf-ribbon_3 PF13248.6 CAM39098.1 - 0.69 9.4 12.4 1.8 8.1 0.2 3.6 4 0 0 4 4 4 0 zinc-ribbon domain Zn_ribbon_SprT PF17283.2 CAM39098.1 - 0.86 9.6 12.7 2.3 8.2 4.7 3.5 2 1 0 2 2 2 0 SprT-like zinc ribbon domain Prok-RING_1 PF14446.6 CAM39098.1 - 1.1 9.2 11.3 0.43 10.6 1.0 2.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 zf-Mss51 PF13824.6 CAM39098.1 - 1.3 9.1 8.7 0.38 10.9 3.5 2.3 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF1356 PF07092.12 CAM39098.1 - 1.6 8.0 5.5 1 8.5 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) zf-RING_7 PF02591.15 CAM39098.1 - 2.3 8.5 6.5 1.3 9.2 0.2 3.0 3 0 0 3 3 3 0 C4-type zinc ribbon domain zf_CopZ PF18423.1 CAM39098.1 - 3 7.9 14.7 2.4 8.2 0.2 3.6 3 1 1 4 4 3 0 Zinc binding domain DUF1272 PF06906.11 CAM39098.1 - 7.4 6.7 10.1 10 6.3 3.6 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1272) zf-C4_Topoisom PF01396.19 CAM39098.1 - 8.2 6.3 11.7 8.3 6.3 0.3 3.3 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger OrfB_Zn_ribbon PF07282.11 CAM39098.1 - 9 6.3 7.9 27 4.8 0.4 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Kelch_1 PF01344.25 CAM39099.2 - 2.3e-05 23.9 0.1 0.13 11.9 0.1 3.0 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.6 CAM39099.2 - 0.0001 22.5 0.1 0.12 12.7 0.0 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CAM39099.2 - 0.00039 20.4 6.5 0.19 11.8 0.0 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CAM39099.2 - 0.012 15.6 2.3 12 6.1 0.4 3.8 3 0 0 3 3 3 0 Kelch motif Orbi_VP6 PF01516.16 CAM39099.2 - 0.023 14.2 0.5 0.063 12.8 0.5 1.7 1 0 0 1 1 1 0 Orbivirus helicase VP6 Metallophos PF00149.28 CAM39100.2 - 1.5e-10 41.9 0.0 2.2e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Spt5-NGN PF03439.13 CAM39100.2 - 0.083 12.8 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Early transcription elongation factor of RNA pol II, NGN section Aconitase_B_N PF11791.8 CAM39100.2 - 0.16 12.1 0.1 0.24 11.5 0.1 1.2 1 0 0 1 1 1 0 Aconitate B N-terminal domain STPPase_N PF16891.5 CAM39100.2 - 0.17 12.4 0.4 0.42 11.1 0.4 1.8 1 1 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain KptA_kDCL PF18176.1 CAM39101.2 - 2e-54 183.9 0.1 5e-54 182.6 0.1 1.8 1 0 0 1 1 1 1 KptA in kinetoplastid DICER domain La_HTH_kDCL PF18177.1 CAM39101.2 - 1.2e-26 92.8 0.0 3.4e-26 91.4 0.0 1.9 1 0 0 1 1 1 1 La HTH in kinetoplastid DICER domain Ribonuclease_3 PF00636.26 CAM39101.2 - 0.041 14.5 0.1 0.78 10.4 0.0 2.7 2 1 0 2 2 2 0 Ribonuclease III domain Sec23_trunk PF04811.15 CAM39103.1 - 2.7e-38 131.9 0.0 5.2e-38 131.0 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CAM39103.1 - 2.2e-21 75.6 0.0 4.1e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 CAM39103.1 - 1.5e-16 60.9 0.2 2.7e-16 60.1 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 CAM39103.1 - 1.3e-11 44.3 0.7 3.2e-11 43.1 0.7 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger VWA_2 PF13519.6 CAM39103.1 - 0.2 12.3 0.0 0.94 10.2 0.0 2.1 3 0 0 3 3 3 0 von Willebrand factor type A domain ASH PF15780.5 CAM39104.2 - 1.2e-07 31.9 2.5 0.0013 18.9 0.1 5.5 6 0 0 6 6 6 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin fn3_5 PF06280.12 CAM39104.2 - 0.14 12.9 0.1 5 7.9 0.0 3.7 3 0 0 3 3 3 0 Fn3-like domain TAP42 PF04177.12 CAM39106.1 - 8.4e-46 156.6 4.4 1.1e-44 152.9 4.4 2.0 1 1 0 1 1 1 1 TAP42-like family ATP_bind_1 PF03029.17 CAM39108.1 - 2.5e-08 34.0 0.0 2.8e-08 33.8 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Aldedh PF00171.22 CAM39109.1 - 1.9e-176 587.1 0.6 2.1e-176 587.0 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 CAM39109.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) LPD7 PF18821.1 CAM39109.1 - 0.17 12.0 0.6 0.97 9.6 0.1 2.2 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 7 SBP_bac_3 PF00497.20 CAM39110.1 - 0.049 13.1 0.0 2.2 7.7 0.0 2.0 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 SMI1_KNR4 PF09346.10 CAM39111.1 - 0.0046 17.3 0.0 0.012 16.0 0.0 1.7 2 0 0 2 2 2 1 SMI1 / KNR4 family (SUKH-1) Acetyltransf_16 PF05301.11 CAM39112.1 - 1.7e-49 167.9 0.0 2.1e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 GNAT acetyltransferase, Mec-17 Acetyltransf_7 PF13508.7 CAM39112.1 - 0.00012 22.4 0.0 0.00027 21.3 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CAM39112.1 - 0.00035 20.8 0.0 0.00081 19.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CAM39112.1 - 0.0043 17.0 0.0 0.011 15.7 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain LMBR1 PF04791.16 CAM39113.1 - 4.2e-32 111.7 33.2 3.2e-22 79.1 12.8 2.1 1 1 1 2 2 2 2 LMBR1-like membrane protein ATP-synt_ab PF00006.25 CAM39114.1 - 7e-64 215.4 0.1 2.7e-63 213.5 0.0 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CAM39114.1 - 2.7e-13 50.2 0.2 6.6e-13 49.0 0.2 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.29 CAM39114.1 - 0.0046 17.4 0.1 0.029 14.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 CAM39114.1 - 0.016 15.5 1.5 0.27 11.5 0.4 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CAM39114.1 - 0.018 14.6 0.2 0.095 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CAM39114.1 - 0.033 13.4 0.1 0.071 12.3 0.1 1.6 1 0 0 1 1 1 0 NB-ARC domain ATPase PF06745.13 CAM39114.1 - 0.036 13.4 0.1 0.062 12.6 0.1 1.4 1 0 0 1 1 1 0 KaiC RsgA_GTPase PF03193.16 CAM39114.1 - 0.07 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase ATPase_2 PF01637.18 CAM39114.1 - 0.1 12.5 0.1 0.25 11.2 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Ribosomal_S25 PF03297.15 CAM39115.1 - 2e-36 124.2 5.4 2.3e-36 124.0 5.4 1.1 1 0 0 1 1 1 1 S25 ribosomal protein DUF3516 PF12029.8 CAM39115.1 - 0.13 11.3 1.4 0.17 10.9 1.4 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3516) DNA_methylase PF00145.17 CAM39116.2 - 3.5e-39 135.1 0.0 4.6e-30 105.1 0.0 3.6 2 1 0 2 2 2 2 C-5 cytosine-specific DNA methylase zinc_ribbon_16 PF17034.5 CAM39120.2 - 3.4e-08 33.8 13.9 3.4e-08 33.8 13.9 2.1 2 1 0 2 2 2 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 CAM39120.2 - 0.0023 17.5 14.0 0.0064 16.1 14.0 1.8 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 CAM39120.2 - 3.4 8.1 13.1 0.49 10.8 7.7 2.5 2 0 0 2 2 2 0 Ring finger domain zinc_ribbon_16 PF17034.5 CAM39121.2 - 0.0023 18.1 23.6 0.024 14.8 23.6 2.3 1 1 0 1 1 1 1 Zinc-ribbon like family AKNA PF12443.8 CAM39122.1 - 0.082 13.6 0.1 0.56 10.9 0.0 2.3 2 0 0 2 2 2 0 AT-hook-containing transcription factor Cullin PF00888.22 CAM39123.1 - 5.7e-50 170.6 0.0 2.2e-49 168.6 0.0 1.7 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CAM39123.1 - 4.3e-07 29.9 0.0 1.1e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain NPL4 PF05021.15 CAM39124.1 - 4.8e-14 52.4 0.0 1.2e-07 31.4 0.0 2.7 2 1 0 2 2 2 2 NPL4 family PRP38 PF03371.15 CAM39125.1 - 5.2e-05 23.2 0.0 8.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 PRP38 family MbeB_N PF04837.12 CAM39125.1 - 0.14 12.5 0.0 0.78 10.1 0.0 2.2 2 0 0 2 2 2 0 MbeB-like, N-term conserved region PPP4R2 PF09184.11 CAM39126.1 - 3.2e-06 26.9 0.0 4.4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 PPP4R2 RNA_pol_N PF01194.17 CAM39127.1 - 1.3e-29 102.3 0.7 1.5e-29 102.0 0.7 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit UBA PF00627.31 CAM39127.1 - 0.078 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 UBA/TS-N domain Metallophos PF00149.28 CAM39128.1 - 2.6e-20 73.8 0.1 3.6e-20 73.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1295 PF06966.12 CAM39129.1 - 1.4e-08 34.5 1.0 2.8e-08 33.6 0.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.13 CAM39129.1 - 0.00014 22.2 0.7 0.00036 20.9 0.6 1.8 1 1 0 1 1 1 1 Phospholipid methyltransferase Steroid_dh PF02544.16 CAM39129.1 - 0.0043 17.1 1.3 0.0065 16.5 0.5 1.7 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 CAM39129.1 - 0.096 13.1 0.1 0.23 11.9 0.1 1.7 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family RF-1 PF00472.20 CAM39130.1 - 4.5e-26 91.1 0.1 7.4e-26 90.4 0.1 1.3 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.18 CAM39130.1 - 1.7e-25 90.1 0.1 1.7e-25 90.1 0.1 1.9 2 0 0 2 2 2 1 PCRF domain UL141 PF16758.5 CAM39130.1 - 0.043 13.5 0.0 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 Herpes-like virus membrane glycoprotein UL141 DUF4910 PF16254.5 CAM39130.1 - 0.099 11.5 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4910) DUF1126 PF06565.12 CAM39131.1 - 2.5e-69 229.8 0.3 2.9e-26 91.3 0.0 3.4 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_7 PF13499.6 CAM39131.1 - 0.00049 20.5 0.5 0.11 12.9 0.0 3.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CAM39131.1 - 0.059 12.9 0.4 9.7 6.0 0.0 3.1 3 0 0 3 3 3 0 EF hand Cyclin_N PF00134.23 CAM39132.1 - 3.5e-37 127.0 0.7 7.3e-37 126.0 0.7 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CAM39132.1 - 2.5e-14 53.4 0.0 4.5e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain NfI_DNAbd_pre-N PF10524.9 CAM39132.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Nuclear factor I protein pre-N-terminus Peptidase_C2 PF00648.21 CAM39134.1 - 3.2e-63 213.5 0.1 5.7e-63 212.7 0.1 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 CAM39134.1 - 1e-24 86.9 0.2 2.3e-24 85.7 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Glyco_transf_92 PF01697.27 CAM39134.1 - 0.0076 15.9 1.1 0.023 14.3 1.1 1.8 1 0 0 1 1 1 1 Glycosyltransferase family 92 Calpain_III PF01067.22 CAM39134.1 - 0.04 14.2 0.2 0.04 14.2 0.2 1.8 2 0 0 2 2 2 0 Calpain large subunit, domain III PSP1 PF04468.12 CAM39135.2 - 9.5e-16 57.9 0.1 1.6e-15 57.1 0.1 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region DUF4542 PF15075.6 CAM39137.1 - 0.11 12.9 4.0 1.3 9.5 4.0 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4542) bZIP_C PF12498.8 CAM39137.1 - 0.14 13.2 2.4 13 6.8 0.1 3.0 2 0 0 2 2 2 0 Basic leucine-zipper C terminal DUF3020 PF11223.8 CAM39137.1 - 0.94 10.0 6.1 23 5.6 0.6 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3020) SLBP_RNA_bind PF15247.6 CAM39138.1 - 7e-23 80.5 3.9 1.8e-22 79.2 3.9 1.8 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain Not3 PF04065.15 CAM39139.2 - 1e-61 208.3 24.4 1e-61 208.3 24.4 1.8 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 CAM39139.2 - 5.4e-34 117.1 9.5 5.4e-34 117.1 9.5 2.3 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 CAM39139.2 - 0.00037 20.8 0.8 0.00037 20.8 0.8 2.9 2 1 0 2 2 2 1 Syntaxin-like protein WD40 PF00400.32 CAM39140.1 - 4.4e-20 71.6 7.9 0.0012 19.6 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM39140.1 - 2.1e-09 37.6 0.0 0.06 13.7 0.0 4.2 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain TPM_phosphatase PF04536.14 CAM39141.1 - 9.6e-17 61.3 0.0 1.3e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 TPM domain zf-IS66 PF13005.7 CAM39141.1 - 0.28 11.6 0.0 0.28 11.6 0.0 3.2 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 DUF883 PF05957.13 CAM39142.2 - 0.24 12.0 6.5 1.5 9.4 0.1 3.7 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Erythro-docking PF09277.11 CAM39142.2 - 0.62 10.0 5.3 8.1 6.4 0.9 4.0 4 1 0 4 4 4 0 Erythronolide synthase, docking Vps55 PF04133.14 CAM39143.1 - 1.8e-28 98.8 3.1 2.1e-28 98.6 3.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Saf_2TM PF18303.1 CAM39143.1 - 0.25 10.9 0.5 12 5.5 0.1 2.4 2 1 0 2 2 2 0 SAVED-fused 2TM effector domain PAC3 PF10178.9 CAM39144.1 - 0.00075 19.6 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 DFP PF04127.15 CAM39145.2 - 1.5e-20 73.8 0.0 1.2e-10 41.5 0.0 2.2 1 1 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein DNA_repr_REX1B PF14966.6 CAM39146.2 - 0.00021 21.9 0.6 0.086 13.5 0.1 2.6 2 0 0 2 2 2 2 DNA repair REX1-B TPR_12 PF13424.6 CAM39147.1 - 5e-10 39.5 31.5 4.2e-05 23.8 3.4 4.0 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_MalT PF17874.1 CAM39147.1 - 3.3e-05 23.4 25.6 0.017 14.5 1.5 2.9 1 1 1 3 3 3 3 MalT-like TPR region SNAP PF14938.6 CAM39147.1 - 0.0019 17.7 3.5 0.0019 17.7 3.5 3.1 1 1 2 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 CAM39147.1 - 0.0035 17.2 15.6 0.0042 17.0 0.5 5.8 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 CAM39147.1 - 0.019 15.6 27.7 0.053 14.2 5.8 4.0 3 2 2 5 5 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 CAM39147.1 - 0.028 14.5 25.2 0.96 9.7 0.2 6.8 6 1 0 6 6 6 0 Tetratricopeptide repeat ANAPC5 PF12862.7 CAM39147.1 - 0.06 13.4 11.4 1.9 8.6 2.1 3.6 2 2 0 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_14 PF13428.6 CAM39147.1 - 0.32 11.9 29.6 1.7 9.6 0.2 7.0 5 1 2 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 CAM39147.1 - 1 9.3 15.6 0.69 9.8 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 CAM39147.1 - 2.5 8.6 11.6 21 5.7 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat KinB_sensor PF16767.5 CAM39147.1 - 3.9 8.0 6.1 17 5.9 0.4 2.9 2 0 0 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB RRM_1 PF00076.22 CAM39148.2 - 0.11 12.3 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kinesin PF00225.23 CAM39150.1 - 1.2e-77 261.1 0.1 1.2e-77 261.1 0.1 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CAM39150.1 - 2.6e-21 76.1 0.0 7.5e-21 74.6 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding HET PF06985.11 CAM39150.1 - 0.098 13.0 0.2 0.3 11.4 0.2 1.8 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) DUF1722 PF08349.11 CAM39150.1 - 0.13 12.6 2.6 0.31 11.3 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) ResIII PF04851.15 CAM39150.1 - 0.22 11.5 0.9 0.61 10.1 0.1 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit FapA PF03961.13 CAM39150.1 - 0.25 9.9 8.8 0.015 13.9 3.8 1.4 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF445 PF04286.12 CAM39150.1 - 0.85 9.4 5.1 1.8 8.3 3.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF445) AAA_16 PF13191.6 CAM39150.1 - 2.6 8.4 6.4 6.1 7.2 0.0 3.6 3 1 0 3 3 3 0 AAA ATPase domain UvrD-helicase PF00580.21 CAM39150.1 - 4.1 6.8 6.5 9.9 5.6 0.0 2.5 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 CAM39150.1 - 6.7 7.0 6.1 3.2 8.0 0.3 2.9 3 0 0 3 3 3 0 AAA domain Acylphosphatase PF00708.18 CAM39151.1 - 1.1e-22 80.2 0.0 1.7e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Acylphosphatase Kinesin PF00225.23 CAM39152.2 - 3.1e-101 338.7 0.0 6.3e-101 337.6 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CAM39152.2 - 7.1e-27 94.2 0.0 7.9e-26 90.8 0.0 2.5 2 0 0 2 2 2 1 Microtubule binding HTH_Mga PF08280.11 CAM39152.2 - 0.026 14.5 0.7 0.08 13.0 0.7 1.7 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain AAA_22 PF13401.6 CAM39152.2 - 0.1 12.9 9.0 0.3 11.3 0.0 3.9 3 0 0 3 3 3 0 AAA domain Pkinase PF00069.25 CAM39154.1 - 2e-57 194.5 0.0 1.2e-42 146.1 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM39154.1 - 5.5e-33 114.3 0.0 2.7e-24 85.8 0.0 2.4 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAM39154.1 - 8.1e-05 21.6 0.0 0.00013 20.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CAM39154.1 - 0.00032 20.1 0.0 0.048 13.0 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 CAM39154.1 - 0.008 16.1 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CAM39154.1 - 0.0099 15.3 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CAM39154.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 CAM39154.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase HpcH_HpaI PF03328.14 CAM39156.1 - 4.3e-54 183.0 0.0 5e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family rRNA_methylase PF06962.12 CAM39156.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative rRNA methylase Zeta_toxin PF06414.12 CAM39157.1 - 0.00037 19.8 0.0 0.17 11.1 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin Rad17 PF03215.15 CAM39157.1 - 0.0015 18.5 0.1 0.0026 17.7 0.1 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain Cytidylate_kin PF02224.18 CAM39157.1 - 0.0033 17.2 0.2 0.025 14.3 0.0 2.2 2 0 0 2 2 2 1 Cytidylate kinase AAA_16 PF13191.6 CAM39157.1 - 0.011 16.1 0.0 0.028 14.8 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain SRP54 PF00448.22 CAM39157.1 - 0.019 14.6 0.6 0.1 12.2 0.5 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Ribosomal_S7 PF00177.21 CAM39157.1 - 0.026 14.2 0.0 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein S7p/S5e AAA_30 PF13604.6 CAM39157.1 - 0.037 13.7 0.3 0.11 12.2 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 CAM39157.1 - 0.041 14.3 0.0 0.12 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain Ploopntkinase2 PF18747.1 CAM39157.1 - 0.052 12.8 0.0 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase2 AAA_22 PF13401.6 CAM39157.1 - 0.069 13.4 0.1 0.18 12.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.14 CAM39157.1 - 0.085 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_18 PF13238.6 CAM39157.1 - 0.11 13.1 0.0 0.22 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain HHH_6 PF14579.6 CAM39157.1 - 0.12 12.7 0.0 0.49 10.7 0.0 2.0 1 1 0 1 1 1 0 Helix-hairpin-helix motif PEPCK_ATP PF01293.20 CAM39157.1 - 0.12 11.0 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 CAM39157.1 - 0.15 12.2 0.1 0.27 11.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain NIF PF03031.18 CAM39158.1 - 5e-49 166.1 0.1 7.6e-49 165.5 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase G-alpha PF00503.20 CAM39158.1 - 0.037 13.2 0.0 0.054 12.7 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit DUF2777 PF10949.8 CAM39158.1 - 0.091 12.4 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2777) RST PF12174.8 CAM39158.1 - 0.18 11.7 2.4 0.19 11.7 0.1 2.1 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain SNF2_N PF00176.23 CAM39160.1 - 1.3e-40 139.3 0.2 2e-40 138.6 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CAM39160.1 - 3.6e-17 62.7 0.0 7.1e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PHD PF00628.29 CAM39160.1 - 8.3e-08 32.0 14.8 0.00028 20.7 4.6 2.6 2 0 0 2 2 2 2 PHD-finger ResIII PF04851.15 CAM39160.1 - 8.7e-07 29.1 0.0 1.4e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-PHD-like PF15446.6 CAM39160.1 - 0.003 17.2 9.1 0.011 15.4 1.5 2.5 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 CAM39160.1 - 0.0059 16.5 3.8 0.0059 16.5 3.8 2.6 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SWI2_SNF2 PF18766.1 CAM39160.1 - 0.014 15.1 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase HDA2-3 PF11496.8 CAM39160.1 - 0.13 11.4 0.0 0.33 10.1 0.0 1.5 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 Prok-RING_1 PF14446.6 CAM39160.1 - 1.9 8.5 20.2 0.88 9.5 7.0 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 SpoIIE PF07228.12 CAM39161.1 - 1.7e-15 57.4 0.0 7e-14 52.2 0.0 2.1 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 CAM39161.1 - 4.2e-05 23.3 0.3 0.0001 22.1 0.3 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 CAM39161.1 - 0.00045 19.9 0.1 0.005 16.5 0.0 2.1 2 0 0 2 2 2 1 Protein phosphatase 2C Rieske PF00355.26 CAM39162.1 - 2.6e-07 30.5 0.3 5.4e-07 29.5 0.3 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 CAM39162.1 - 4.2e-06 26.6 0.0 7.4e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain GTP_EFTU PF00009.27 CAM39163.1 - 3.8e-50 170.2 0.0 5.9e-50 169.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CAM39163.1 - 2.3e-15 56.4 0.0 5e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CAM39163.1 - 4.2e-06 27.0 0.0 9.8e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 CAM39163.1 - 3.8e-05 23.4 0.0 9.4e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 CAM39163.1 - 0.0005 20.1 0.0 0.0024 17.9 0.0 2.1 2 0 0 2 2 2 1 Elongation Factor G, domain II Poly_export PF02563.16 CAM39163.1 - 0.16 12.2 0.0 4.8 7.5 0.0 2.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis/export protein RsgA_GTPase PF03193.16 CAM39163.1 - 0.17 11.7 0.2 0.37 10.7 0.2 1.5 1 0 0 1 1 1 0 RsgA GTPase cobW PF02492.19 CAM39163.1 - 0.18 11.4 0.0 0.36 10.4 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain mRNA_triPase PF02940.15 CAM39165.1 - 8.1e-13 48.6 0.0 2.2e-11 43.9 0.0 2.4 1 1 0 1 1 1 1 mRNA capping enzyme, beta chain HCV_NS5a_1b PF08301.13 CAM39165.1 - 0.0083 16.7 0.6 0.069 13.7 0.0 2.6 3 0 0 3 3 3 1 Hepatitis C virus non-structural 5a domain 1b PRTP PF01366.18 CAM39165.1 - 0.049 11.7 0.0 0.059 11.4 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein TPR_2 PF07719.17 CAM39166.1 - 2.2e-19 67.9 28.6 0.0065 16.5 0.0 7.3 6 1 1 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 CAM39166.1 - 1.3e-15 56.5 24.2 0.00015 21.4 0.1 6.9 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 CAM39166.1 - 2.3e-08 33.6 25.2 0.087 13.1 0.1 6.9 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 CAM39166.1 - 2.4e-08 34.1 15.8 0.00093 19.4 1.5 4.7 3 3 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 CAM39166.1 - 1.6e-06 28.4 12.4 0.63 11.0 0.0 6.5 3 2 3 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 CAM39166.1 - 2.4e-05 24.8 11.6 0.52 10.9 0.1 4.7 2 2 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 CAM39166.1 - 7.3e-05 22.4 23.6 1 9.1 0.6 7.3 5 2 2 7 7 7 3 TPR repeat zf-C2H2_10 PF16588.5 CAM39166.1 - 0.00011 21.9 3.5 0.00029 20.5 3.5 1.7 1 0 0 1 1 1 1 C2H2 zinc-finger Fis1_TPR_C PF14853.6 CAM39166.1 - 0.00014 21.9 4.1 0.078 13.1 0.0 3.5 3 0 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.6 CAM39166.1 - 0.00077 20.1 20.1 0.61 10.8 2.5 5.0 2 2 2 5 5 5 3 Tetratricopeptide repeat NYD-SP12_N PF15015.6 CAM39166.1 - 0.0039 15.6 0.3 0.014 13.8 0.1 1.9 2 0 0 2 2 2 1 Spermatogenesis-associated, N-terminal TPR_17 PF13431.6 CAM39166.1 - 0.011 16.1 8.9 1.4 9.4 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat zf-CCHC PF00098.23 CAM39166.1 - 0.018 15.1 1.3 0.038 14.1 1.3 1.6 1 0 0 1 1 1 0 Zinc knuckle MIT PF04212.18 CAM39166.1 - 0.043 13.9 12.6 1.2 9.2 0.3 4.4 3 2 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 CAM39166.1 - 0.89 10.3 11.5 17 6.3 0.1 5.7 6 1 0 6 6 5 0 Tetratricopeptide repeat KBP_C PF12309.8 CAM39167.1 - 3.8e-46 158.3 3.4 2.9e-45 155.3 2.2 2.4 2 1 0 2 2 2 1 KIF-1 binding protein C terminal eIF3_subunit PF08597.10 CAM39168.1 - 5.2e-07 29.8 11.8 8e-07 29.2 11.8 1.3 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Pinin_SDK_memA PF04696.13 CAM39168.1 - 1.1 9.3 8.4 4.6 7.3 3.4 2.2 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region CoA_binding PF02629.19 CAM39169.1 - 2.9e-26 92.0 3.7 3.8e-26 91.6 2.3 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 CAM39169.1 - 2.6e-22 79.3 1.5 2.7e-22 79.2 0.1 1.7 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.6 CAM39169.1 - 9.1e-08 32.0 0.0 1.8e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 CAM39169.1 - 0.00017 22.1 0.1 0.00032 21.2 0.1 1.5 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 CAM39170.1 - 2.9e-26 92.0 3.7 3.8e-26 91.6 2.3 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 CAM39170.1 - 2.6e-22 79.3 1.5 2.7e-22 79.2 0.1 1.7 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.6 CAM39170.1 - 9.1e-08 32.0 0.0 1.8e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 CAM39170.1 - 0.00017 22.1 0.1 0.00032 21.2 0.1 1.5 1 0 0 1 1 1 1 CoA binding domain BRO1 PF03097.18 CAM39171.1 - 7.1e-23 81.0 0.2 9e-23 80.7 0.2 1.1 1 0 0 1 1 1 1 BRO1-like domain UPF0449 PF15136.6 CAM39172.1 - 0.097 13.1 0.6 0.19 12.2 0.6 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 ubiquitin PF00240.23 CAM39173.2 - 7.5e-06 25.6 0.0 1.3e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CAM39173.2 - 1.9e-05 24.4 0.3 3.3e-05 23.6 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CLP1_P PF16575.5 CAM39174.1 - 1.5e-15 57.5 0.0 2.8e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 CAM39174.1 - 2.8e-07 30.7 0.0 4.4e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Sec1 PF00995.23 CAM39175.1 - 1.1e-89 302.2 0.0 1.4e-89 301.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family ATP-synt_F PF01990.17 CAM39175.1 - 0.0097 16.2 0.9 1.5 9.2 0.0 3.5 3 1 0 3 3 3 1 ATP synthase (F/14-kDa) subunit DUF2730 PF10805.8 CAM39175.1 - 0.1 12.7 0.1 0.25 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DnaJ PF00226.31 CAM39176.1 - 7.9e-23 80.4 5.1 1.8e-22 79.2 5.1 1.6 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 CAM39176.1 - 3.9e-10 39.7 6.3 8e-10 38.7 6.3 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CAM39176.1 - 4.9e-08 33.1 3.0 9e-08 32.3 3.0 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CAM39176.1 - 4.4e-05 23.8 0.3 0.0002 21.7 0.1 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 CAM39176.1 - 0.011 16.5 0.9 0.034 15.0 0.4 2.1 2 0 0 2 2 1 0 C2H2-type zinc finger AKAP95 PF04988.12 CAM39176.1 - 0.012 15.9 0.2 0.03 14.6 0.2 1.7 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2 PF00096.26 CAM39176.1 - 0.012 16.0 1.4 0.025 15.0 1.4 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type ABATE PF07336.11 CAM39176.1 - 0.18 12.5 4.8 0.38 11.4 4.8 1.5 1 0 0 1 1 1 0 Putative stress-induced transcription regulator HNH_5 PF14279.6 CAM39176.1 - 0.2 11.5 0.6 0.39 10.6 0.6 1.4 1 0 0 1 1 1 0 HNH endonuclease DUF4136 PF13590.6 CAM39176.1 - 0.24 12.0 4.5 0.71 10.5 4.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4136) zf-H2C2_2 PF13465.6 CAM39176.1 - 3 8.4 5.0 0.45 11.0 0.6 1.9 2 0 0 2 2 2 0 Zinc-finger double domain ParcG PF10274.9 CAM39177.2 - 1.4e-78 263.2 0.0 1.9e-78 262.8 0.0 1.2 1 0 0 1 1 1 1 Parkin co-regulated protein PCI PF01399.27 CAM39178.1 - 6.3e-07 29.9 0.1 1.8e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 CAM39178.1 - 0.42 10.9 5.5 5.7 7.3 0.2 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 CAM39178.1 - 2.9 8.3 7.6 14 6.1 0.1 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat PhaP_Bmeg PF09602.10 CAM39179.1 - 0.049 13.6 4.2 1.7 8.5 1.1 2.5 1 1 1 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF3135 PF11333.8 CAM39179.1 - 0.057 13.7 5.3 34 4.8 0.1 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3135) Gp-FAR-1 PF05823.12 CAM39179.1 - 0.066 13.6 0.1 0.14 12.5 0.1 1.5 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Fib_alpha PF08702.10 CAM39179.1 - 0.074 13.2 4.7 0.12 12.6 1.0 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4004 PF13171.6 CAM39179.1 - 0.088 13.0 1.3 0.21 11.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4004) Cytochrom_B562 PF07361.11 CAM39179.1 - 0.12 13.0 3.7 0.25 12.0 1.7 2.5 1 1 0 1 1 1 0 Cytochrome b562 SOAR PF16533.5 CAM39179.1 - 0.38 10.7 6.8 4.4 7.3 0.8 2.9 2 0 0 2 2 2 0 STIM1 Orai1-activating region CSN5_C PF18323.1 CAM39179.1 - 0.43 11.5 2.9 1.9 9.5 0.4 2.7 1 1 1 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain Phage_holin_7_1 PF16081.5 CAM39179.1 - 1.6 8.9 5.4 1 9.5 0.1 2.9 1 1 1 3 3 3 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family SNARE PF05739.19 CAM39179.1 - 6.5 6.8 5.4 21 5.2 0.6 2.8 2 0 0 2 2 2 0 SNARE domain Golgin_A5 PF09787.9 CAM39179.1 - 7.6 5.9 18.2 52 3.2 0.5 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 Pex2_Pex12 PF04757.14 CAM39180.1 - 1.1e-28 100.4 13.6 1.4e-28 100.1 13.6 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 CAM39180.1 - 0.011 15.9 8.9 0.021 15.0 8.9 1.5 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 CAM39180.1 - 0.024 14.5 13.0 0.038 13.9 13.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TFIIS_C PF01096.18 CAM39180.1 - 0.18 11.7 6.0 0.47 10.3 6.0 1.7 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS) zf-C3HC4_3 PF13920.6 CAM39180.1 - 0.21 11.5 13.9 0.3 11.0 13.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TF_Zn_Ribbon PF08271.12 CAM39180.1 - 0.27 10.8 6.0 0.11 12.0 2.2 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding zf-RING_5 PF14634.6 CAM39180.1 - 0.62 10.1 12.9 1 9.4 12.9 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 CAM39180.1 - 0.97 9.5 9.8 1.8 8.6 9.8 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 CAM39180.1 - 1.3 9.4 11.2 2.2 8.7 11.2 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 CAM39180.1 - 2.9 7.8 9.4 8.1 6.4 9.5 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 CAM39181.1 - 4.8e-06 26.4 14.9 8.3e-06 25.6 7.9 2.5 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 CAM39181.1 - 0.0032 17.1 4.8 0.012 15.2 1.2 2.1 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain SCAB-Ig PF16709.5 CAM39181.1 - 0.08 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Ig domain of plant-specific actin-binding protein DUF1719 PF08224.11 CAM39181.1 - 0.098 11.8 0.6 0.15 11.1 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1719) zf-C4_ClpX PF06689.13 CAM39181.1 - 0.35 10.8 3.4 1.9 8.5 3.4 2.1 1 1 0 1 1 1 0 ClpX C4-type zinc finger PHD_4 PF16866.5 CAM39181.1 - 3.4 7.8 10.4 28 4.9 10.5 2.2 1 1 0 1 1 1 0 PHD-finger UbiA PF01040.18 CAM39183.2 - 0.075 12.3 0.0 0.094 12.0 0.0 1.1 1 0 0 1 1 1 0 UbiA prenyltransferase family Pex2_Pex12 PF04757.14 CAM39187.2 - 2.1e-12 47.2 0.2 2.7e-05 23.9 0.0 2.2 1 1 1 2 2 2 2 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 CAM39187.2 - 3.5e-09 36.4 10.8 8.6e-09 35.1 10.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CAM39187.2 - 2.9e-08 33.9 13.0 2.9e-08 33.9 13.0 1.9 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.6 CAM39187.2 - 2.6e-07 30.5 10.7 2.6e-07 30.5 10.7 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CAM39187.2 - 9.1e-06 25.4 12.0 9.1e-06 25.4 12.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CAM39187.2 - 1.2e-05 25.1 10.8 1.2e-05 25.1 10.8 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CAM39187.2 - 1.4e-05 25.3 9.2 2e-05 24.8 7.9 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CAM39187.2 - 3e-05 24.0 5.8 6.9e-05 22.8 5.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 CAM39187.2 - 3.8e-05 23.7 11.5 0.00014 21.9 11.5 2.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 CAM39187.2 - 0.0006 19.8 8.0 0.0027 17.7 8.1 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CAM39187.2 - 0.0016 18.2 11.8 0.0016 18.2 11.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) TRAM_LAG1_CLN8 PF03798.16 CAM39187.2 - 0.044 13.5 0.2 0.11 12.2 0.2 1.7 1 0 0 1 1 1 0 TLC domain DUF4381 PF14316.6 CAM39187.2 - 0.099 12.9 0.0 0.43 10.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Zn_ribbon_17 PF17120.5 CAM39187.2 - 1.1 8.9 9.0 2.9 7.6 9.0 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-Di19 PF05605.12 CAM39187.2 - 1.5 9.2 7.7 0.64 10.4 0.2 3.1 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DUF4352 PF11611.8 CAM39189.2 - 0.0048 17.2 0.1 0.0087 16.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4352) RNase_II_C_S1 PF18614.1 CAM39189.2 - 0.035 14.1 0.2 0.082 12.9 0.2 1.6 1 0 0 1 1 1 0 RNase II-type exonuclease C-terminal S1 domain SPC12 PF06645.13 CAM39190.1 - 3.8e-08 33.3 0.3 5e-08 32.9 0.3 1.2 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) VPS9 PF02204.18 CAM39191.1 - 7.9e-14 51.7 0.0 1.2e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain MORN PF02493.20 CAM39191.1 - 5.6e-08 32.2 7.0 5e-06 26.1 0.5 4.0 3 0 0 3 3 3 3 MORN repeat Pkinase PF00069.25 CAM39192.1 - 1.4e-65 221.3 0.0 1.8e-65 220.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM39192.1 - 2.3e-39 135.3 0.0 3.1e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM39192.1 - 4e-06 26.4 0.0 7.5e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CAM39192.1 - 0.0084 16.1 0.0 0.21 11.5 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CAM39192.1 - 0.015 14.6 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ADK PF00406.22 CAM39195.2 - 1e-36 126.3 0.0 1.2e-36 126.1 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CAM39195.2 - 7.7e-19 68.5 0.0 1.2e-18 67.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 CAM39195.2 - 1.6e-11 44.0 3.0 2.6e-11 43.3 3.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid A2L_zn_ribbon PF08792.10 CAM39195.2 - 0.0015 18.2 0.9 0.35 10.6 0.0 2.4 2 0 0 2 2 2 2 A2L zinc ribbon domain AAA_18 PF13238.6 CAM39195.2 - 0.0022 18.5 0.0 0.0033 18.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CAM39195.2 - 0.0033 17.6 0.0 0.0052 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain zf-C2H2_3 PF13878.6 CAM39195.2 - 0.12 12.3 1.7 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Arv1 PF04161.13 CAM39198.1 - 5.4e-29 101.9 6.1 7.9e-29 101.3 6.1 1.3 1 0 0 1 1 1 1 Arv1-like family PH_12 PF16457.5 CAM39199.1 - 0.0093 16.5 4.9 0.01 16.3 0.0 3.6 4 1 0 4 4 4 1 Pleckstrin homology domain Peptidase_M24 PF00557.24 CAM39201.1 - 1.6e-42 145.6 0.7 3.8e-42 144.3 0.1 1.8 2 0 0 2 2 2 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 CAM39201.1 - 2.5e-38 131.7 0.0 4e-37 127.8 0.0 2.4 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 CAM39201.1 - 3.6e-19 68.6 0.2 1.2e-18 66.9 0.0 2.1 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 CAM39201.1 - 1.7e-17 64.3 0.1 7.6e-14 52.5 0.1 2.6 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain RNase_T PF00929.24 CAM39202.1 - 1.7e-06 28.6 0.0 2.8e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Cluap1 PF10234.9 CAM39203.1 - 9.2e-91 303.9 14.6 1.3e-90 303.5 14.6 1.2 1 0 0 1 1 1 1 Clusterin-associated protein-1 Lectin_N PF03954.14 CAM39203.1 - 3.2 7.5 6.8 0.58 9.9 1.0 2.4 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Ras PF00071.22 CAM39204.1 - 2.1e-50 170.5 0.0 2.6e-50 170.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAM39204.1 - 6.3e-32 110.3 0.0 1.1e-31 109.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAM39204.1 - 5.2e-11 42.3 0.0 6.9e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CAM39204.1 - 0.00027 20.3 0.0 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RNA_helicase PF00910.22 CAM39204.1 - 0.00033 21.0 0.2 0.0021 18.4 0.2 2.0 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 CAM39204.1 - 0.00033 20.7 0.0 0.00054 20.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CAM39204.1 - 0.0081 16.1 0.0 2.9 7.8 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 CAM39204.1 - 0.0092 15.2 1.1 1.3 8.1 0.1 2.7 2 1 1 3 3 3 1 G-protein alpha subunit GTP_EFTU PF00009.27 CAM39204.1 - 0.019 14.5 0.5 0.075 12.6 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 CAM39204.1 - 0.029 13.9 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 CAM39204.1 - 0.037 14.2 0.0 0.054 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 CAM39204.1 - 0.041 13.4 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein cobW PF02492.19 CAM39204.1 - 0.077 12.6 0.1 3.7 7.1 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 CAM39204.1 - 0.081 13.3 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 CAM39204.1 - 0.098 12.4 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CAM39204.1 - 0.098 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Septin PF00735.18 CAM39204.1 - 0.1 11.8 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Septin DNA_pol_D_N PF18018.1 CAM39205.1 - 1.1e-24 86.9 0.0 2.3e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 CAM39205.1 - 4.9e-24 84.9 0.9 4.8e-22 78.4 0.9 2.2 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Surp PF01805.20 CAM39206.1 - 1.2e-13 50.9 0.5 3.5e-10 39.7 0.0 2.4 2 0 0 2 2 2 2 Surp module DUF442 PF04273.13 CAM39207.1 - 0.12 12.5 0.7 22 5.2 0.1 2.4 2 0 0 2 2 2 0 Putative phosphatase (DUF442) zf-AN1 PF01428.16 CAM39209.1 - 0.033 14.4 28.0 0.038 14.1 8.5 2.5 2 0 0 2 2 2 0 AN1-like Zinc finger PPR PF01535.20 CAM39211.1 - 0.00021 21.3 0.2 0.0022 18.1 0.0 2.5 2 0 0 2 2 2 1 PPR repeat PPR_1 PF12854.7 CAM39211.1 - 0.0054 16.4 0.0 0.02 14.6 0.0 2.1 1 0 0 1 1 1 1 PPR repeat PPR_2 PF13041.6 CAM39211.1 - 0.0062 16.7 0.4 0.033 14.4 0.0 2.4 2 1 1 3 3 3 1 PPR repeat family PPR_3 PF13812.6 CAM39211.1 - 0.0088 16.1 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR_long PF17177.4 CAM39211.1 - 0.021 14.2 0.1 0.031 13.7 0.1 1.2 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP RNA_pol_Rpb2_6 PF00562.28 CAM39212.2 - 1.3e-72 245.1 0.0 1.2e-71 241.9 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.16 CAM39212.2 - 4e-19 68.5 0.0 1e-18 67.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 CAM39212.2 - 2.5e-14 53.5 0.0 6.8e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.12 CAM39212.2 - 6.6e-12 45.3 0.0 2e-11 43.7 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_1 PF04563.15 CAM39212.2 - 3.3e-08 33.3 0.0 1.3e-07 31.3 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase beta subunit zinc_ribbon_10 PF10058.9 CAM39212.2 - 0.13 12.0 0.1 0.37 10.5 0.1 1.7 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Raptor_N PF14538.6 CAM39213.1 - 2.3e-44 150.9 0.0 4.4e-44 150.0 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT PF02985.22 CAM39213.1 - 0.00023 21.2 1.9 0.11 12.9 0.1 3.4 2 0 0 2 2 2 2 HEAT repeat NopRA1 PF16201.5 CAM39213.1 - 0.1 12.1 0.1 0.49 9.9 0.1 2.1 2 0 0 2 2 2 0 Nucleolar pre-ribosomal-associated protein 1 HEAT_2 PF13646.6 CAM39213.1 - 0.12 12.8 1.2 0.73 10.3 0.0 2.8 2 1 1 3 3 3 0 HEAT repeats Cnd1 PF12717.7 CAM39213.1 - 0.17 11.9 0.5 0.64 10.0 0.2 2.1 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF2475 PF10629.9 CAM39214.1 - 0.046 13.9 0.7 0.12 12.6 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2475) Ins_beta PF03488.14 CAM39216.1 - 0.074 13.1 0.1 0.19 11.8 0.0 1.6 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type Herpes_TK PF00693.18 CAM39216.1 - 0.12 11.6 0.1 0.16 11.2 0.1 1.1 1 0 0 1 1 1 0 Thymidine kinase from herpesvirus PreAtp-grasp PF18604.1 CAM39216.1 - 0.13 11.9 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Pre ATP-grasp domain Y_phosphatase2 PF03162.13 CAM39217.1 - 7.6e-35 119.9 0.0 1.5e-26 92.9 0.0 2.1 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CAM39217.1 - 0.00046 20.2 0.0 0.00063 19.8 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family DnaJ PF00226.31 CAM39218.1 - 0.0073 16.4 0.1 0.018 15.1 0.0 1.7 2 0 0 2 2 2 1 DnaJ domain SP_C-Propep PF08999.10 CAM39218.1 - 0.037 13.8 0.1 0.064 13.0 0.1 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide DUF5578 PF17741.1 CAM39219.1 - 6.7e-14 52.0 0.0 0.00018 21.0 0.0 3.3 3 0 0 3 3 3 3 Family of unknown function (DUF5578) LSM14 PF12701.7 CAM39220.1 - 2.1e-26 91.8 0.1 3.2e-26 91.2 0.1 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 CAM39220.1 - 4.2e-06 26.8 0.0 7.4e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain FDF PF09532.10 CAM39220.1 - 0.00057 20.7 15.6 0.31 11.9 5.5 2.4 1 1 1 2 2 2 2 FDF domain Steroid_dh PF02544.16 CAM39221.1 - 4.7e-25 88.3 3.7 7.9e-25 87.6 3.7 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 CAM39221.1 - 6.1e-06 25.9 2.1 9.2e-06 25.3 1.9 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) YukD PF08817.10 CAM39221.1 - 0.03 15.0 0.1 0.069 13.8 0.1 1.6 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD PEMT PF04191.13 CAM39221.1 - 0.16 12.3 5.2 0.16 12.4 0.7 2.4 1 1 1 2 2 2 0 Phospholipid methyltransferase ubiquitin PF00240.23 CAM39221.1 - 0.19 11.5 0.1 0.87 9.4 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin family RMI1_N PF08585.12 CAM39222.2 - 2.8e-09 37.1 0.4 1.1e-08 35.1 0.4 1.9 1 1 0 1 1 1 1 RecQ mediated genome instability protein BRCA-2_OB1 PF09103.10 CAM39222.2 - 0.053 13.5 0.0 0.11 12.5 0.0 1.5 1 1 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 DUF1935 PF09149.10 CAM39223.1 - 2.3e-27 95.4 0.0 2.7e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) SARAF PF06682.12 CAM39224.1 - 9 5.8 11.5 56 3.2 0.0 2.2 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Glyco_transf_5 PF08323.11 CAM39226.1 - 0.1 12.2 0.1 0.31 10.7 0.1 1.7 1 0 0 1 1 1 0 Starch synthase catalytic domain Transket_pyr PF02779.24 CAM39227.1 - 6.4e-45 153.0 0.1 9.4e-45 152.5 0.1 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CAM39227.1 - 1.5e-39 134.6 0.0 4.2e-39 133.3 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 CAM39227.1 - 0.073 13.4 0.0 0.42 10.9 0.0 2.3 2 0 0 2 2 2 0 Pyruvate:ferredoxin oxidoreductase core domain II LSM PF01423.22 CAM39228.1 - 2.6e-14 52.7 0.0 3.5e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CAM39228.1 - 0.019 15.1 0.2 0.19 11.9 0.2 2.0 1 1 0 1 1 1 0 Ataxin 2 SM domain LRR_9 PF14580.6 CAM39229.2 - 1.3e-13 50.9 0.0 2.7e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CAM39229.2 - 3.8e-09 36.7 2.0 8.6e-05 22.8 0.1 3.3 2 1 3 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM39229.2 - 7.2e-09 35.3 5.8 9.9e-08 31.6 2.0 2.7 2 0 0 2 2 2 1 Leucine rich repeat LRR_6 PF13516.6 CAM39229.2 - 6.1e-05 22.8 0.9 2.2 8.6 0.0 3.8 3 0 0 3 3 3 2 Leucine Rich repeat DUF3349 PF11829.8 CAM39229.2 - 0.017 15.9 0.0 0.051 14.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3349) LRR_1 PF00560.33 CAM39229.2 - 1.4 9.8 2.8 1e+02 4.1 0.1 3.8 3 1 1 4 4 4 0 Leucine Rich Repeat HSCB_C PF07743.13 CAM39230.1 - 0.0068 16.9 0.0 0.15 12.6 0.0 2.5 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 CAM39230.1 - 0.0079 16.3 1.5 0.055 13.6 0.2 2.5 2 0 0 2 2 2 1 DnaJ domain TPR_12 PF13424.6 CAM39231.1 - 1.1e-16 60.8 24.5 1e-06 29.0 4.6 6.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 CAM39231.1 - 1.2e-05 25.0 10.5 0.47 10.7 0.1 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 CAM39231.1 - 0.63 10.4 1.9 3 8.3 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat SUIM_assoc PF16619.5 CAM39231.1 - 1.8 8.7 6.7 6.9 6.8 6.7 2.0 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TPR_1 PF00515.28 CAM39231.1 - 4.3 7.3 9.1 51 3.9 0.6 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 CAM39231.1 - 4.4 7.6 5.2 12 6.2 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CAM39231.1 - 5.5 7.8 13.3 9.2 7.2 0.7 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_33 PF13671.6 CAM39231.1 - 5.9 7.1 6.6 3.3 7.9 3.8 2.1 2 0 0 2 2 2 0 AAA domain TFIIA PF03153.13 CAM39231.1 - 9.1 6.2 12.8 21 5.0 12.8 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HORMA PF02301.18 CAM39232.1 - 4e-16 59.3 0.0 6.5e-16 58.6 0.0 1.3 1 1 0 1 1 1 1 HORMA domain VWA_3 PF13768.6 CAM39232.1 - 0.068 13.1 0.0 0.099 12.6 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain bacHORMA_2 PF18173.1 CAM39232.1 - 0.094 12.6 0.5 0.23 11.3 0.0 1.8 2 1 0 2 2 2 0 Bacterial HORMA domain 2 EFP_N PF08207.12 CAM39234.1 - 9.8e-06 25.5 0.4 1.7e-05 24.7 0.4 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain CHCH PF06747.13 CAM39235.1 - 0.00039 20.5 4.3 0.033 14.3 0.6 2.4 2 0 0 2 2 2 2 CHCH domain COX6B PF02297.17 CAM39235.1 - 0.068 13.4 2.9 0.12 12.6 2.9 1.4 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb CX9C PF16860.5 CAM39235.1 - 0.12 12.4 0.4 0.12 12.4 0.4 2.2 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, OS-D PF03392.13 CAM39235.1 - 0.18 11.9 3.6 11 6.2 0.1 2.0 1 1 1 2 2 2 0 Insect pheromone-binding family, A10/OS-D DUF1016_N PF17761.1 CAM39236.1 - 0.003 17.7 0.1 0.014 15.6 0.0 1.9 2 0 0 2 2 2 1 DUF1016 N-terminal domain ribosomal_L24 PF17136.4 CAM39236.1 - 0.012 16.0 0.1 0.025 15.0 0.1 1.6 1 0 0 1 1 1 0 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 CAM39236.1 - 0.022 14.7 1.0 0.055 13.4 1.0 1.7 1 0 0 1 1 1 0 KOW motif DAGAT PF03982.13 CAM39237.1 - 2.9e-73 246.4 0.0 3.7e-73 246.0 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase SSFA2_C PF14723.6 CAM39237.1 - 0.15 12.0 0.2 0.28 11.1 0.2 1.5 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus GIT_SHD PF08518.11 CAM39239.1 - 0.34 10.6 7.9 2.2 8.0 0.2 3.5 4 0 0 4 4 4 0 Spa2 homology domain (SHD) of GIT WD40 PF00400.32 CAM39240.1 - 3.1e-15 56.3 13.1 1.6 9.8 0.1 9.9 9 0 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM39240.1 - 1.5e-06 28.4 0.2 0.052 13.8 0.0 4.4 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CAM39240.1 - 0.13 11.2 0.1 0.34 9.8 0.1 1.7 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein BRCT PF00533.26 CAM39241.1 - 0.00013 22.2 0.0 0.012 16.0 0.0 3.0 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CAM39241.1 - 0.015 15.7 0.0 0.44 11.0 0.0 2.8 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain Pkinase PF00069.25 CAM39242.1 - 2.9e-25 89.1 0.0 8.5e-20 71.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM39242.1 - 1.7e-12 47.2 0.0 3e-08 33.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAM39242.1 - 3.6e-06 26.0 0.0 6.1e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CAM39242.1 - 0.024 14.6 0.0 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family TRAPPC-Trs85 PF12739.7 CAM39243.1 - 2.3e-33 115.8 0.1 4.4e-33 114.9 0.1 1.4 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit MFS18 PF17352.2 CAM39243.1 - 0.016 15.6 3.8 0.23 11.8 1.0 2.7 2 0 0 2 2 2 0 Male Flower Specific protein 18 BBE PF08031.12 CAM39243.1 - 0.1 12.7 0.0 0.97 9.6 0.0 2.3 2 0 0 2 2 2 0 Berberine and berberine like TPR_1 PF00515.28 CAM39243.1 - 0.46 10.4 2.1 2.1 8.3 0.3 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3020 PF11223.8 CAM39244.1 - 1.7 9.2 14.4 24 5.5 0.6 4.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3020) DUF576 PF04507.12 CAM39244.1 - 4.4 6.7 6.2 66 2.8 0.2 3.2 3 0 0 3 3 3 0 Csa1 family Thioredoxin PF00085.20 CAM39245.1 - 0.013 15.5 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin zinc_ribbon_16 PF17034.5 CAM39246.2 - 6.1e-05 23.2 13.1 0.06 13.6 6.7 2.6 2 0 0 2 2 2 2 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 CAM39246.2 - 0.52 10.0 22.1 0.02 14.5 13.9 2.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type CHAP PF05257.16 CAM39247.1 - 5.1e-05 23.8 0.0 0.0001 22.8 0.0 1.6 1 0 0 1 1 1 1 CHAP domain Dala_Dala_lig_C PF07478.13 CAM39248.1 - 1.9e-13 50.4 0.0 3.6e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus SET PF00856.28 CAM39248.1 - 1.1e-06 29.2 0.9 7.7e-06 26.4 0.0 2.8 3 1 0 3 3 3 1 SET domain ATP-grasp_3 PF02655.14 CAM39248.1 - 0.00037 20.6 0.0 0.0017 18.4 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 CAM39248.1 - 0.0049 16.5 0.0 0.009 15.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 CAM39248.1 - 0.0051 16.4 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 CAM39248.1 - 0.012 15.3 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATP-synt_ab PF00006.25 CAM39249.1 - 2.1e-37 128.9 0.2 1.3e-36 126.2 0.0 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain T3SS_ATPase_C PF18269.1 CAM39249.1 - 0.043 13.7 0.2 0.21 11.5 0.2 2.2 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain ATP-synt_ab_N PF02874.23 CAM39250.2 - 7.4e-14 52.0 0.2 1.4e-13 51.1 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab PF00006.25 CAM39250.2 - 1.7e-08 34.4 0.3 3.3e-08 33.4 0.3 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.22 CAM39250.2 - 0.033 13.4 0.1 0.043 13.0 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.6 CAM39250.2 - 0.05 13.9 0.4 0.092 13.1 0.4 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CAM39250.2 - 0.23 11.0 0.1 0.37 10.3 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Trs65 PF12735.7 CAM39251.1 - 0.0043 16.5 0.1 0.25 10.7 0.0 3.0 3 0 0 3 3 3 1 TRAPP trafficking subunit Trs65 Pkinase PF00069.25 CAM39252.1 - 1.9e-25 89.7 0.0 6.2e-14 52.0 0.0 3.5 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM39252.1 - 5e-06 26.0 0.0 0.82 8.9 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 CAM39252.1 - 0.24 10.3 0.1 0.37 9.7 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase zf-Tim10_DDP PF02953.15 CAM39253.1 - 0.0016 18.1 0.2 0.0028 17.3 0.2 1.5 1 1 0 1 1 1 1 Tim10/DDP family zinc finger ABC_ATPase PF09818.9 CAM39254.1 - 1.1e-169 565.1 0.0 1.4e-169 564.7 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.6 CAM39254.1 - 0.0033 18.0 0.0 0.0052 17.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain Pkinase PF00069.25 CAM39256.1 - 1.8e-42 145.5 0.0 2.5e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM39256.1 - 8.4e-30 103.9 0.0 1.2e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAM39256.1 - 3e-06 26.3 0.0 4.8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CAM39256.1 - 0.0003 20.2 0.0 0.00044 19.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CAM39256.1 - 0.027 14.4 2.2 0.07 13.0 0.1 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family Methyltr_RsmB-F PF01189.17 CAM39258.1 - 1.9e-22 79.9 0.1 1e-15 57.9 0.0 2.2 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F PUA PF01472.20 CAM39258.1 - 2.3e-07 30.7 0.2 4.5e-07 29.7 0.2 1.3 1 0 0 1 1 1 1 PUA domain RVT_1 PF00078.27 CAM39259.1 - 0.0027 17.3 0.0 0.007 15.9 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A17 PF05380.13 CAM39259.1 - 0.027 14.5 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 Pao retrotransposon peptidase Phage_integrase PF00589.22 CAM39260.1 - 9.3e-07 28.8 0.0 6.1e-06 26.1 0.0 2.4 2 1 0 2 2 2 1 Phage integrase family RVT_1 PF00078.27 CAM39260.1 - 0.0019 17.8 0.0 0.0054 16.3 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A17 PF05380.13 CAM39260.1 - 0.002 18.2 0.1 0.036 14.1 0.0 2.3 1 1 1 2 2 2 1 Pao retrotransposon peptidase Phage_integrase PF00589.22 CAM39261.1 - 4.4e-06 26.6 0.0 4.1e-05 23.5 0.0 2.5 2 1 0 2 2 2 1 Phage integrase family RVT_1 PF00078.27 CAM39261.1 - 0.0011 18.6 0.0 0.0027 17.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A17 PF05380.13 CAM39261.1 - 0.0012 18.9 0.1 0.026 14.5 0.0 2.3 1 1 1 2 2 2 1 Pao retrotransposon peptidase RPAP1_N PF08621.10 CAM39261.1 - 1.9 8.3 3.7 0.75 9.6 0.3 2.1 2 0 0 2 2 2 0 RPAP1-like, N-terminal LSM PF01423.22 CAM39264.1 - 4e-13 48.9 0.0 5.2e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 LSM domain DUF2642 PF10842.8 CAM39264.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2642) Brix PF04427.18 CAM39265.1 - 1.6e-28 100.1 0.0 2.1e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 Brix domain Glyoxalase_4 PF13669.6 CAM39266.1 - 4.5e-18 65.5 0.0 5.5e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 CAM39266.1 - 0.021 14.9 0.0 0.025 14.7 0.0 1.1 1 0 0 1 1 1 0 Glyoxalase-like domain Glyoxalase PF00903.25 CAM39266.1 - 0.032 14.4 0.0 0.04 14.1 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily GDC-P PF02347.16 CAM39267.1 - 1e-170 568.3 0.0 6.6e-156 519.4 0.1 3.1 3 0 0 3 3 3 3 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 CAM39267.1 - 0.0021 17.4 0.0 0.0055 16.0 0.0 1.6 2 0 0 2 2 2 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 CAM39267.1 - 0.0054 15.3 0.1 0.016 13.8 0.0 1.8 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme DUF4473 PF14747.6 CAM39267.1 - 0.015 15.8 0.0 0.07 13.7 0.0 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) Pkinase PF00069.25 CAM39268.1 - 7e-57 192.8 0.0 7.9e-57 192.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM39268.1 - 2.9e-22 79.2 0.0 3.1e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM39268.1 - 0.0017 17.8 0.0 0.0063 15.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 CAM39268.1 - 0.032 13.9 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CAM39268.1 - 0.093 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Rhomboid PF01694.22 CAM39273.1 - 3.8e-05 23.7 1.1 8.4e-05 22.6 1.1 1.6 1 1 0 1 1 1 1 Rhomboid family MauE PF07291.11 CAM39273.1 - 0.048 13.4 0.1 0.077 12.8 0.1 1.3 1 0 0 1 1 1 0 Methylamine utilisation protein MauE Pribosyltran PF00156.27 CAM39274.2 - 2.4e-09 36.9 0.3 3e-09 36.6 0.3 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyltran PF00156.27 CAM39275.1 - 3.8e-19 68.8 0.0 4.9e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CAM39275.1 - 0.00073 19.0 0.0 0.00099 18.6 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 CAM39275.1 - 0.038 13.5 0.0 0.057 12.9 0.0 1.5 1 1 0 1 1 1 0 Phosphoribosyl transferase MCM_bind PF09739.9 CAM39276.1 - 2.9e-37 128.4 0.0 1.5e-36 126.0 0.0 1.8 1 1 0 1 1 1 1 Mini-chromosome maintenance replisome factor NIF PF03031.18 CAM39277.1 - 6.6e-50 168.9 0.2 1.1e-49 168.1 0.1 1.4 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase zf_PR_Knuckle PF18445.1 CAM39277.1 - 0.038 13.8 0.0 0.084 12.7 0.0 1.5 1 0 0 1 1 1 0 PR zinc knuckle motif HAD PF12710.7 CAM39277.1 - 0.15 12.4 0.1 1 9.7 0.0 1.9 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Ribosomal_L30 PF00327.20 CAM39278.1 - 1.5e-18 66.4 2.2 1.5e-18 66.4 2.2 2.1 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 CAM39278.1 - 2.2e-15 56.7 11.0 4.1e-15 55.8 11.0 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 CAM39279.1 - 1.7e-18 66.2 2.2 1.7e-18 66.2 2.2 2.1 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 CAM39279.1 - 2.5e-15 56.5 11.0 4.6e-15 55.6 11.0 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain DUF2062 PF09835.9 CAM39280.1 - 2.1e-06 27.7 4.0 2.4e-06 27.5 4.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2062) NifU PF01106.17 CAM39281.1 - 9.7e-27 92.9 0.0 2.7e-26 91.5 0.0 1.8 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.11 CAM39281.1 - 2e-21 75.8 0.0 3.6e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal eRF1_1 PF03463.15 CAM39282.1 - 4.8e-32 110.7 0.3 1e-31 109.6 0.1 1.7 2 0 0 2 2 2 1 eRF1 domain 1 eRF1_2 PF03464.15 CAM39282.1 - 2.1e-18 66.9 0.1 3.3e-18 66.3 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CAM39282.1 - 1.1e-13 51.7 0.0 4e-13 49.8 0.0 2.0 2 1 0 2 2 2 1 eRF1 domain 3 DUF3145 PF11343.8 CAM39282.1 - 0.093 12.3 0.0 0.29 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3145) LIDHydrolase PF10230.9 CAM39287.1 - 6.8e-62 209.4 0.0 7.9e-62 209.2 0.0 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 CAM39287.1 - 4.2e-10 39.3 0.0 5.1e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CAM39287.1 - 3e-07 30.3 0.0 3e-06 27.1 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CAM39287.1 - 3.8e-05 24.4 0.0 5.9e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 CAM39287.1 - 0.0047 17.1 0.0 0.0083 16.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain DUF1057 PF06342.12 CAM39287.1 - 0.006 15.7 0.0 0.0078 15.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_5 PF12695.7 CAM39287.1 - 0.031 14.0 0.1 0.15 11.8 0.1 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 CAM39287.1 - 0.044 13.5 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 CAM39287.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) IF4E PF01652.18 CAM39289.1 - 8.5e-13 48.4 0.0 1e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E TipAS PF07739.13 CAM39291.1 - 0.0095 16.5 1.9 3.2 8.3 0.0 3.6 4 0 0 4 4 4 2 TipAS antibiotic-recognition domain MMR_HSR1 PF01926.23 CAM39292.1 - 7.8e-43 145.2 0.1 2.5e-20 72.7 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CAM39292.1 - 4.4e-25 88.4 1.2 8.5e-13 48.3 0.0 3.9 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CAM39292.1 - 2.8e-19 69.2 0.2 4.8e-09 35.9 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B Dynamin_N PF00350.23 CAM39292.1 - 1.5e-18 67.4 0.1 0.0013 18.8 0.0 4.4 3 1 1 4 4 4 3 Dynamin family AIG1 PF04548.16 CAM39292.1 - 2.3e-14 53.2 0.3 1.1e-06 28.2 0.0 2.8 3 1 0 3 3 2 2 AIG1 family Roc PF08477.13 CAM39292.1 - 2.7e-13 50.2 0.0 6.3e-06 26.4 0.0 3.1 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase KH_dom-like PF14714.6 CAM39292.1 - 4.7e-13 49.3 0.5 1.1e-12 48.1 0.5 1.6 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal RsgA_GTPase PF03193.16 CAM39292.1 - 9.9e-13 48.3 0.5 0.011 15.7 0.0 4.3 2 1 2 4 4 4 3 RsgA GTPase SRPRB PF09439.10 CAM39292.1 - 1.2e-11 44.4 0.0 5.8e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit Ras PF00071.22 CAM39292.1 - 8.6e-11 41.7 0.0 1.6e-06 27.8 0.0 2.6 2 1 0 2 2 2 2 Ras family ABC_tran PF00005.27 CAM39292.1 - 5.5e-06 26.9 0.0 0.11 13.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter MMR_HSR1_Xtn PF16897.5 CAM39292.1 - 1e-05 25.5 0.0 0.065 13.3 0.0 2.9 3 0 0 3 3 3 2 C-terminal region of MMR_HSR1 domain PduV-EutP PF10662.9 CAM39292.1 - 1.7e-05 24.6 0.0 0.3 10.8 0.0 3.5 2 2 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 CAM39292.1 - 1.9e-05 24.1 0.0 0.011 15.0 0.0 2.4 2 0 0 2 2 2 2 Septin cobW PF02492.19 CAM39292.1 - 5.1e-05 22.9 1.9 0.12 11.9 0.3 3.7 3 1 1 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain IIGP PF05049.13 CAM39292.1 - 7.5e-05 22.0 0.0 0.014 14.5 0.0 2.5 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) Arf PF00025.21 CAM39292.1 - 0.00011 21.7 0.9 0.093 12.2 0.1 3.4 2 2 0 2 2 2 1 ADP-ribosylation factor family GBP PF02263.19 CAM39292.1 - 0.0011 18.3 0.0 0.65 9.2 0.0 2.3 2 0 0 2 2 2 2 Guanylate-binding protein, N-terminal domain TniB PF05621.11 CAM39292.1 - 0.0021 17.5 0.0 0.12 11.7 0.0 2.5 2 0 0 2 2 2 1 Bacterial TniB protein T2SSE PF00437.20 CAM39292.1 - 0.0028 16.8 0.0 0.0083 15.2 0.0 1.8 1 1 0 1 1 1 1 Type II/IV secretion system protein MobB PF03205.14 CAM39292.1 - 0.011 15.7 0.0 0.19 11.7 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_21 PF13304.6 CAM39292.1 - 0.024 14.5 0.0 5.3 6.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CAM39292.1 - 0.028 14.1 0.0 7 6.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain CLP1_P PF16575.5 CAM39292.1 - 0.03 14.1 1.1 14 5.5 0.0 3.6 2 1 1 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop FtsK_SpoIIIE PF01580.18 CAM39292.1 - 0.04 13.3 0.0 1.1 8.5 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.6 CAM39292.1 - 0.047 14.2 0.2 24 5.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain ATPase_2 PF01637.18 CAM39292.1 - 0.051 13.5 0.0 2.4 8.0 0.0 2.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Pox_A32 PF04665.12 CAM39292.1 - 0.06 12.8 0.1 2.4 7.5 0.0 2.8 3 0 0 3 3 3 0 Poxvirus A32 protein G-alpha PF00503.20 CAM39292.1 - 0.066 12.4 0.1 4.2 6.4 0.0 2.8 2 1 0 3 3 3 0 G-protein alpha subunit AAA_22 PF13401.6 CAM39292.1 - 0.066 13.5 0.0 5.5 7.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 CAM39292.1 - 0.11 13.1 0.0 7.5 7.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 CAM39292.1 - 0.2 11.3 0.0 14 5.2 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain NUDIX_2 PF13869.6 CAM39294.2 - 2.1e-40 138.3 0.0 2.4e-39 134.9 0.0 2.4 1 1 0 1 1 1 1 Nucleotide hydrolase 6PF2K PF01591.18 CAM39296.1 - 5.7e-34 117.4 0.0 8.7e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CAM39296.1 - 3.7e-14 52.9 0.0 2.5e-12 46.9 0.0 2.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ank_5 PF13857.6 CAM39296.1 - 1.1e-12 47.8 0.1 2.6e-12 46.7 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 CAM39296.1 - 8.1e-11 42.2 0.1 1.1e-06 29.0 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CAM39296.1 - 1.3e-10 41.7 0.0 6.6e-10 39.4 0.0 2.1 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 CAM39296.1 - 1.2e-07 31.9 0.1 0.00027 21.2 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat AAA_33 PF13671.6 CAM39296.1 - 2.7e-07 30.9 0.1 5.4e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain Ank_3 PF13606.6 CAM39296.1 - 1.6e-06 28.0 0.0 0.0022 18.3 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat KTI12 PF08433.10 CAM39296.1 - 0.00056 19.4 0.0 0.0012 18.3 0.0 1.6 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_5 PF07728.14 CAM39296.1 - 0.02 14.9 0.2 0.073 13.1 0.2 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 CAM39296.1 - 0.037 14.4 0.1 0.13 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 CAM39296.1 - 0.13 12.2 0.1 0.73 9.7 0.0 2.1 1 1 1 2 2 2 0 Adenylylsulphate kinase AAA_17 PF13207.6 CAM39296.1 - 0.15 12.5 0.1 0.74 10.2 0.1 2.1 1 1 0 1 1 1 0 AAA domain THF_DHG_CYH_C PF02882.19 CAM39297.1 - 5.4e-60 201.3 0.3 8.5e-60 200.7 0.3 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 CAM39297.1 - 2.3e-35 121.3 0.3 3.5e-35 120.8 0.3 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Cyclin_N PF00134.23 CAM39298.1 - 3.7e-13 49.3 0.4 1.2e-12 47.7 0.1 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CAM39298.1 - 0.0019 18.2 3.1 0.0024 17.9 0.9 2.3 2 1 0 2 2 2 1 Cyclin, C-terminal domain HARE-HTH PF05066.13 CAM39298.1 - 0.029 14.8 0.1 5.7 7.4 0.0 3.2 3 0 0 3 3 3 0 HB1, ASXL, restriction endonuclease HTH domain APC_r PF05923.12 CAM39298.1 - 0.076 12.8 2.2 6.6 6.6 0.0 2.8 3 0 0 3 3 3 0 APC repeat Vps52 PF04129.12 CAM39299.2 - 4.6e-47 160.9 3.3 1.1e-14 54.1 0.0 3.4 3 1 0 3 3 3 3 Vps52 / Sac2 family DASH_Duo1 PF08651.10 CAM39299.2 - 0.00056 19.6 2.2 0.082 12.7 0.6 3.2 4 0 0 4 4 4 2 DASH complex subunit Duo1 DHR10 PF18595.1 CAM39299.2 - 0.11 12.6 0.1 0.31 11.1 0.1 1.8 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain TPR_2 PF07719.17 CAM39301.1 - 4.4e-27 92.0 39.5 0.00068 19.6 0.2 14.7 16 1 0 16 16 15 5 Tetratricopeptide repeat TPR_1 PF00515.28 CAM39301.1 - 9.5e-26 88.5 21.3 0.002 17.9 0.0 11.1 13 0 0 13 13 12 5 Tetratricopeptide repeat TPR_12 PF13424.6 CAM39301.1 - 5.3e-21 74.7 35.1 0.0017 18.6 0.0 10.8 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_8 PF13181.6 CAM39301.1 - 2.1e-19 68.0 11.8 0.21 11.9 0.0 12.6 15 0 0 15 15 13 4 Tetratricopeptide repeat TPR_16 PF13432.6 CAM39301.1 - 2.6e-17 63.2 30.8 0.0037 17.9 0.4 9.8 8 2 0 8 8 8 5 Tetratricopeptide repeat TPR_9 PF13371.6 CAM39301.1 - 1.4e-14 54.0 28.8 0.032 14.4 0.1 10.1 7 2 3 10 10 10 5 Tetratricopeptide repeat TPR_11 PF13414.6 CAM39301.1 - 9.2e-12 44.5 5.3 0.4 10.4 0.0 7.8 7 0 0 7 7 7 3 TPR repeat TPR_14 PF13428.6 CAM39301.1 - 7.9e-08 32.5 39.7 0.064 14.1 0.4 12.3 12 2 2 14 14 13 2 Tetratricopeptide repeat TPR_19 PF14559.6 CAM39301.1 - 1.5e-07 31.8 17.1 0.067 13.7 0.0 8.8 8 2 2 10 10 10 2 Tetratricopeptide repeat TPR_10 PF13374.6 CAM39301.1 - 6.5e-06 25.9 33.7 2.1 8.3 0.1 10.6 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_17 PF13431.6 CAM39301.1 - 2.2e-05 24.5 10.6 0.5 10.9 0.1 7.5 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 CAM39301.1 - 0.00011 22.6 18.0 16 6.4 0.0 10.1 11 0 0 11 11 10 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CAM39301.1 - 0.00062 19.9 7.9 14 6.0 0.0 7.0 5 1 2 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 CAM39301.1 - 0.0031 16.5 0.4 0.45 9.4 0.0 2.9 3 0 0 3 3 3 1 NMDA receptor-regulated protein 1 SHNi-TPR PF10516.9 CAM39301.1 - 0.031 13.7 9.0 1.8 8.1 0.0 5.9 7 0 0 7 7 7 0 SHNi-TPR Fis1_TPR_C PF14853.6 CAM39301.1 - 0.041 14.0 4.3 1.9 8.6 0.0 5.0 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat ANAPC5 PF12862.7 CAM39301.1 - 0.068 13.3 7.0 1.7 8.8 0.1 5.3 5 2 0 5 5 5 0 Anaphase-promoting complex subunit 5 TPR_7 PF13176.6 CAM39301.1 - 0.45 10.7 32.9 2.2 8.5 0.1 10.4 12 0 0 12 12 11 0 Tetratricopeptide repeat Ist1 PF03398.14 CAM39302.1 - 9.9e-44 149.1 0.1 1.2e-43 148.9 0.1 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Ret2_MD PF18528.1 CAM39303.1 - 1.9e-49 166.0 0.2 3.2e-49 165.2 0.2 1.4 1 0 0 1 1 1 1 RNA editing 3' terminal uridylyl transferase 2 middle domain PAP_assoc PF03828.19 CAM39303.1 - 3.2e-15 56.1 0.1 6.3e-15 55.1 0.1 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CAM39303.1 - 1.3e-05 25.4 0.0 2.7e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 CAM39303.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase 2OG-FeII_Oxy_2 PF13532.6 CAM39304.2 - 5.2e-12 46.4 0.0 7.4e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pan_kinase PF03309.14 CAM39304.2 - 0.08 12.8 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Type III pantothenate kinase zf-B_box PF00643.24 CAM39305.1 - 0.012 15.7 10.3 0.049 13.8 5.0 2.9 3 0 0 3 3 3 0 B-box zinc finger DUF1091 PF06477.13 CAM39305.1 - 0.02 15.4 0.1 0.029 14.8 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1091) DUF3090 PF11290.8 CAM39305.1 - 0.083 12.7 1.0 0.28 11.0 1.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3090) zf-DNL PF05180.12 CAM39305.1 - 7.4 6.6 10.3 5.2 7.1 0.1 2.5 2 1 0 2 2 2 0 DNL zinc finger PseudoU_synth_1 PF01416.20 CAM39306.2 - 8.7e-05 22.9 0.0 0.0017 18.8 0.0 2.6 2 0 0 2 2 2 1 tRNA pseudouridine synthase ParA PF10609.9 CAM39307.1 - 2e-92 309.1 0.0 6.6e-91 304.1 0.0 2.0 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CAM39307.1 - 5.5e-11 42.6 0.0 1.1e-09 38.4 0.0 2.1 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CAM39307.1 - 3.3e-07 30.4 1.2 2.8e-06 27.4 1.2 2.1 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 CAM39307.1 - 6.2e-06 25.6 0.5 4.2e-05 22.9 0.3 2.2 3 0 0 3 3 3 1 Anion-transporting ATPase MipZ PF09140.11 CAM39307.1 - 1.2e-05 24.8 0.3 0.00023 20.6 0.2 2.1 2 0 0 2 2 2 1 ATPase MipZ AAA_25 PF13481.6 CAM39307.1 - 0.00022 20.9 0.1 0.00045 19.9 0.1 1.4 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 CAM39307.1 - 0.014 14.8 0.2 0.034 13.6 0.1 1.6 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family APS_kinase PF01583.20 CAM39307.1 - 0.025 14.5 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.22 CAM39307.1 - 0.034 13.3 0.3 0.068 12.3 0.3 1.4 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 CAM39307.1 - 0.035 14.0 0.5 0.075 12.9 0.5 1.5 1 0 0 1 1 1 0 NACHT domain CBP_BcsQ PF06564.12 CAM39307.1 - 0.052 13.0 0.2 0.14 11.7 0.2 1.7 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ MeaB PF03308.16 CAM39307.1 - 0.055 12.4 0.2 0.095 11.7 0.2 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Hpr_kinase_C PF07475.12 CAM39307.1 - 0.098 12.2 0.2 0.8 9.2 0.4 2.0 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain RsgA_GTPase PF03193.16 CAM39307.1 - 0.2 11.6 0.3 0.41 10.5 0.3 1.5 1 0 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 CAM39307.1 - 0.2 11.4 0.1 0.56 9.9 0.1 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF1358 PF07096.11 CAM39308.1 - 0.00053 20.0 0.1 0.001 19.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1358) ATP-synt_C PF00137.21 CAM39310.1 - 1.3e-08 35.0 12.4 2.4e-08 34.2 12.4 1.4 1 0 0 1 1 1 1 ATP synthase subunit C DUF2474 PF10617.9 CAM39311.1 - 0.063 13.1 0.3 0.18 11.7 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2474) Cbl_N PF02262.16 CAM39311.1 - 0.08 12.9 0.1 3.5 7.6 0.0 2.5 2 0 0 2 2 2 0 CBL proto-oncogene N-terminal domain 1 ATP_bind_1 PF03029.17 CAM39312.1 - 8.6e-48 163.2 0.0 7e-46 157.0 0.0 2.7 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 CAM39312.1 - 0.0061 16.7 0.0 0.029 14.5 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CAM39312.1 - 0.016 15.5 0.0 0.13 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 CAM39312.1 - 0.044 14.2 1.0 0.45 10.9 0.3 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CAM39312.1 - 0.051 14.0 0.0 0.63 10.5 0.0 2.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CAM39312.1 - 0.092 13.3 0.3 0.092 13.3 0.3 3.0 2 2 0 2 2 2 0 AAA domain PAP_assoc PF03828.19 CAM39313.1 - 8.2e-08 32.3 0.1 1.9e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CAM39313.1 - 0.031 14.6 0.0 0.059 13.7 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyltransferase domain LRR_6 PF13516.6 CAM39314.1 - 6.9e-32 106.8 27.4 0.0012 18.8 0.0 12.3 12 0 0 12 12 12 10 Leucine Rich repeat LRR_4 PF12799.7 CAM39314.1 - 2.5e-06 27.7 17.3 0.089 13.2 0.3 6.6 3 3 4 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CAM39314.1 - 0.00055 20.1 10.7 47 5.1 0.2 8.1 7 3 0 7 7 7 0 Leucine Rich Repeat LRR_8 PF13855.6 CAM39314.1 - 0.024 14.4 27.1 0.18 11.6 2.2 7.9 4 2 4 8 8 8 0 Leucine rich repeat FAA_hydrolase_N PF09298.11 CAM39314.1 - 0.11 12.7 3.0 0.11 12.6 0.5 2.1 2 1 1 3 3 3 0 Fumarylacetoacetase N-terminal Glycos_transf_2 PF00535.26 CAM39318.2 - 0.0066 16.3 0.0 0.071 12.9 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 SecG PF03840.14 CAM39318.2 - 0.16 12.1 1.6 0.24 11.5 0.1 2.0 2 0 0 2 2 2 0 Preprotein translocase SecG subunit MAPKK1_Int PF08923.10 CAM39320.1 - 0.00044 20.1 0.0 0.021 14.6 0.0 2.0 2 0 0 2 2 2 2 Mitogen-activated protein kinase kinase 1 interacting DUF525 PF04379.14 CAM39321.1 - 8.5e-16 58.0 0.0 1.9e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 ApaG domain DUF883 PF05957.13 CAM39322.2 - 8.6 7.0 9.2 0.47 11.1 0.7 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Taxilin PF09728.9 CAM39323.1 - 2.1e-07 30.5 49.0 2.8e-07 30.0 49.0 1.2 1 0 0 1 1 1 1 Myosin-like coiled-coil protein Fib_alpha PF08702.10 CAM39323.1 - 0.034 14.3 29.2 0.16 12.1 8.2 3.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Laminin_II PF06009.12 CAM39323.1 - 0.43 10.6 27.1 0.23 11.5 1.5 4.0 2 1 2 4 4 4 0 Laminin Domain II Filament PF00038.21 CAM39323.1 - 2.7 7.5 47.3 0.21 11.1 20.7 2.7 1 1 2 3 3 3 0 Intermediate filament protein Lectin_N PF03954.14 CAM39323.1 - 2.9 7.7 17.6 0.5 10.1 4.4 3.8 2 2 2 4 4 4 0 Hepatic lectin, N-terminal domain Syntaxin-6_N PF09177.11 CAM39323.1 - 3 8.5 28.2 1 10.0 5.2 4.1 2 2 1 3 3 3 0 Syntaxin 6, N-terminal PPR_2 PF13041.6 CAM39324.1 - 1.2e-13 51.0 3.7 5.3e-07 29.7 0.1 4.0 2 2 2 4 4 4 4 PPR repeat family PPR_3 PF13812.6 CAM39324.1 - 2e-10 40.6 0.0 7.2e-06 26.0 0.0 2.6 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR PF01535.20 CAM39324.1 - 1.1e-05 25.4 8.9 0.073 13.3 0.0 5.0 5 1 0 5 5 5 2 PPR repeat PPR_long PF17177.4 CAM39324.1 - 1.3e-05 24.6 0.3 0.0015 17.9 0.1 2.1 1 1 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 CAM39324.1 - 0.14 13.1 0.8 49 5.1 0.1 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat PemK_toxin PF02452.17 CAM39324.1 - 0.14 12.6 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system MNE1 PF13762.6 CAM39324.1 - 0.16 11.9 0.3 3.8 7.5 0.0 2.8 2 1 1 3 3 3 0 Mitochondrial splicing apparatus component Cpn10 PF00166.21 CAM39325.1 - 8.1e-24 83.5 0.1 9.1e-24 83.3 0.1 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cpn10 PF00166.21 CAM39327.1 - 7.9e-24 83.5 0.2 8.8e-24 83.4 0.2 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit DUF4821 PF16092.5 CAM39328.1 - 4.4e-14 52.8 0.0 1.4e-12 47.8 0.0 2.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4821) Pyr_redox_2 PF07992.14 CAM39328.1 - 4.4e-06 26.1 0.0 9.1e-06 25.1 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thioredoxin PF00085.20 CAM39329.1 - 2.4e-23 82.1 0.0 2e-10 40.6 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 CAM39329.1 - 1.5e-15 57.8 0.4 3.4e-15 56.7 0.1 1.8 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 CAM39329.1 - 4.8e-09 36.0 0.0 4.1e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family HyaE PF07449.11 CAM39329.1 - 0.00011 22.1 0.1 0.75 9.8 0.0 2.6 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Thioredoxin PF00085.20 CAM39330.1 - 4.3e-19 68.4 0.0 5.6e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CAM39330.1 - 1.2e-05 25.6 0.0 0.026 14.8 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 CAM39330.1 - 0.00056 19.3 0.0 0.0014 18.1 0.0 1.6 1 1 1 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 CAM39330.1 - 0.0051 17.2 0.1 0.017 15.6 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CAM39330.1 - 0.025 14.8 0.0 0.048 13.9 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like TraF PF13728.6 CAM39330.1 - 0.042 13.7 0.0 0.064 13.1 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein DUF2012 PF09430.10 CAM39331.1 - 3.9e-33 114.2 0.1 5.2e-33 113.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.6 CAM39331.1 - 0.0018 18.5 0.1 0.0032 17.7 0.1 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain SpaA PF17802.1 CAM39331.1 - 0.045 14.1 0.0 0.067 13.5 0.0 1.3 1 0 0 1 1 1 0 Prealbumin-like fold domain CarbopepD_reg_2 PF13715.6 CAM39331.1 - 0.16 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 CarboxypepD_reg-like domain SNARE PF05739.19 CAM39332.1 - 2e-08 34.1 1.2 2e-08 34.1 1.2 2.2 3 0 0 3 3 3 1 SNARE domain Syntaxin-6_N PF09177.11 CAM39332.1 - 0.00023 21.7 4.3 0.00029 21.3 0.3 2.4 1 1 1 2 2 2 1 Syntaxin 6, N-terminal DUF632 PF04782.12 CAM39332.1 - 0.013 14.8 1.8 0.019 14.3 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF632) DASH_Duo1 PF08651.10 CAM39332.1 - 0.05 13.4 0.6 1.3 8.8 0.0 3.3 3 2 1 4 4 4 0 DASH complex subunit Duo1 TBCA PF02970.16 CAM39332.1 - 0.052 13.9 0.5 0.052 13.9 0.5 3.0 1 1 3 4 4 4 0 Tubulin binding cofactor A Laminin_II PF06009.12 CAM39332.1 - 0.054 13.5 4.8 0.35 10.9 0.2 2.4 2 0 0 2 2 2 0 Laminin Domain II PGM_PMM_II PF02879.16 CAM39332.1 - 0.085 13.5 0.3 16 6.2 0.0 2.3 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Snapin_Pallidin PF14712.6 CAM39332.1 - 0.18 12.2 8.2 2.6 8.5 1.5 2.8 2 1 0 2 2 2 0 Snapin/Pallidin T3SSipB PF16535.5 CAM39332.1 - 0.28 11.6 6.8 0.51 10.8 0.1 2.3 1 1 1 2 2 2 0 Type III cell invasion protein SipB DUF2951 PF11166.8 CAM39332.1 - 0.39 11.0 5.9 0.099 12.9 1.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) EMP24_GP25L PF01105.24 CAM39332.1 - 2.5 8.0 5.2 1 9.3 0.5 2.2 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Fib_alpha PF08702.10 CAM39332.1 - 3.8 7.7 8.5 3.9 7.6 5.0 2.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Pentapeptide_4 PF13599.6 CAM39333.2 - 2.8e-08 33.8 3.2 7.2e-07 29.3 0.2 3.3 2 1 1 3 3 3 2 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 CAM39333.2 - 1.7e-06 27.5 0.0 1.7e-06 27.5 0.0 4.0 5 0 0 5 5 5 1 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 CAM39333.2 - 8e-05 22.7 0.0 0.0016 18.5 0.1 3.9 2 1 2 4 4 4 3 Pentapeptide repeats (9 copies) DAGK_cat PF00781.24 CAM39334.1 - 1.1e-12 47.7 0.5 5.7e-11 42.1 0.0 2.9 3 0 0 3 3 3 1 Diacylglycerol kinase catalytic domain DUF1064 PF06356.11 CAM39334.1 - 0.038 14.3 0.0 0.07 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1064) RCC1 PF00415.18 CAM39337.1 - 9.2e-72 237.5 46.2 1.7e-16 60.6 0.5 12.5 11 2 0 11 11 11 10 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CAM39337.1 - 4.5e-37 125.1 75.3 1.3e-07 31.2 1.4 11.3 12 0 0 12 12 12 8 Regulator of chromosome condensation (RCC1) repeat GAD-like PF08887.11 CAM39337.1 - 0.014 15.1 0.4 19 5.1 0.0 3.5 3 0 0 3 3 3 0 GAD-like domain Hira PF07569.11 CAM39337.1 - 0.024 14.3 0.8 18 5.0 0.0 3.8 4 0 0 4 4 4 0 TUP1-like enhancer of split Methyltransf_9 PF08003.11 CAM39337.1 - 0.2 10.6 0.1 8.3 5.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) RCC1 PF00415.18 CAM39338.1 - 3.2e-62 206.9 33.4 2.7e-12 47.1 0.2 12.6 12 0 0 12 12 12 10 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CAM39338.1 - 3.3e-30 103.2 57.7 2.3e-05 24.1 0.4 12.6 13 0 0 13 13 13 9 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 CAM39338.1 - 0.017 14.8 0.0 0.47 10.1 0.0 2.9 3 0 0 3 3 3 0 TUP1-like enhancer of split DUF4213 PF13938.6 CAM39338.1 - 1.1 9.5 6.6 2.2 8.6 0.2 4.2 4 0 0 4 4 4 0 Putative heavy-metal chelation RRM_1 PF00076.22 CAM39339.1 - 1e-10 41.2 0.1 1.6e-10 40.6 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 CAM39341.1 - 2.9e-06 27.0 0.0 4.1e-05 23.3 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GSHPx PF00255.19 CAM39343.1 - 3.1e-22 78.2 0.1 4.3e-22 77.8 0.1 1.2 1 0 0 1 1 1 1 Glutathione peroxidase GSHPx PF00255.19 CAM39344.1 - 1.3e-38 130.9 0.6 1.6e-38 130.6 0.6 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 CAM39344.1 - 4.7e-06 26.5 0.1 9e-06 25.6 0.1 1.5 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 CAM39344.1 - 0.00011 21.9 0.0 0.001 18.8 0.0 2.0 2 0 0 2 2 2 1 Redoxin GSHPx PF00255.19 CAM39345.1 - 5.7e-39 132.0 0.5 7.2e-39 131.7 0.5 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 CAM39345.1 - 2.9e-06 27.2 0.1 5.7e-06 26.3 0.1 1.5 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 CAM39345.1 - 7.4e-05 22.5 0.0 0.00067 19.4 0.0 2.0 2 0 0 2 2 2 1 Redoxin AsnA PF03590.15 CAM39346.1 - 1.4e-94 316.1 0.0 1.8e-94 315.8 0.0 1.1 1 0 0 1 1 1 1 Aspartate-ammonia ligase tRNA-synt_2 PF00152.20 CAM39346.1 - 0.0046 16.1 0.1 0.011 14.8 0.1 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) Anophelin PF10731.9 CAM39347.1 - 5.7 6.9 5.8 2 8.3 0.7 2.8 3 0 0 3 3 3 0 Thrombin inhibitor from mosquito IF3_N PF05198.16 CAM39348.2 - 0.039 14.2 0.0 0.081 13.2 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain Exo_endo_phos PF03372.23 CAM39349.1 - 1.6e-06 27.8 0.0 2e-05 24.2 0.0 2.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family XRN_N PF03159.18 CAM39349.1 - 0.00025 20.5 0.1 0.00084 18.8 0.1 1.7 1 1 1 2 2 2 1 XRN 5'-3' exonuclease N-terminus Ribosomal_S9 PF00380.19 CAM39351.1 - 1.6e-26 93.2 0.9 1.8e-26 93.0 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_S9 PF00380.19 CAM39352.1 - 1.6e-26 93.2 0.9 1.8e-26 93.0 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 HSP70 PF00012.20 CAM39353.1 - 1.7e-76 257.7 0.0 2.5e-39 135.0 0.0 2.4 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 CAM39353.1 - 0.00067 18.6 0.1 0.21 10.4 0.0 3.1 2 1 1 3 3 3 2 MreB/Mbl protein OGFr_N PF04664.13 CAM39354.1 - 1.4e-07 31.2 0.3 0.00045 19.8 0.0 2.2 2 0 0 2 2 2 2 Opioid growth factor receptor (OGFr) conserved region DNA_pol3_delt_C PF14840.6 CAM39354.1 - 0.1 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Processivity clamp loader gamma complex DNA pol III C-term PIF1 PF05970.14 CAM39356.1 - 2.7e-05 23.5 0.0 4.9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase IstB_IS21 PF01695.17 CAM39356.1 - 0.00027 20.7 0.3 0.0025 17.6 0.0 2.4 3 0 0 3 3 3 1 IstB-like ATP binding protein SRP54 PF00448.22 CAM39356.1 - 0.0049 16.5 0.0 0.0092 15.6 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Viral_env_E26 PF11050.8 CAM39356.1 - 0.039 13.3 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 Virus envelope protein E26 Bac_DnaA PF00308.18 CAM39356.1 - 0.08 12.8 0.0 0.28 11.0 0.0 1.8 2 0 0 2 2 2 0 Bacterial dnaA protein DUF815 PF05673.13 CAM39356.1 - 0.16 11.1 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Nitro_FeMo-Co PF02579.17 CAM39356.1 - 0.19 12.1 0.1 0.42 11.0 0.1 1.5 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor DUF3395 PF11875.8 CAM39357.1 - 6.5e-42 143.1 0.0 1.1e-41 142.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 CAM39357.1 - 1.5e-15 57.1 0.1 2.5e-15 56.3 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Flagellin_C PF00700.21 CAM39357.1 - 0.088 13.2 0.4 21 5.5 0.1 2.6 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region Mcp5_PH PF12814.7 CAM39358.1 - 1.5e-22 80.0 1.9 3.6e-22 78.8 1.9 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology LcrR PF09621.10 CAM39358.1 - 0.17 11.4 0.4 0.42 10.1 0.2 1.7 2 0 0 2 2 2 0 Type III secretion system regulator (LcrR) NDUF_B12 PF08122.12 CAM39359.2 - 0.2 11.7 2.5 0.39 10.8 0.4 2.7 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family NMD3 PF04981.13 CAM39360.1 - 4e-76 255.7 2.2 4e-76 255.7 2.2 1.4 2 0 0 2 2 2 1 NMD3 family DZR PF12773.7 CAM39360.1 - 1.9 8.6 11.5 1.8 8.6 3.5 2.8 2 1 1 3 3 3 0 Double zinc ribbon Pkinase PF00069.25 CAM39361.1 - 2.1e-29 102.7 0.0 6.4e-29 101.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM39361.1 - 5.4e-12 45.5 0.0 3.9e-06 26.3 0.0 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 CAM39361.1 - 0.24 10.4 0.0 0.35 9.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PRKCSH-like PF12999.7 CAM39363.1 - 4.8e-38 130.7 2.0 8.9e-38 129.8 2.0 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 CAM39363.1 - 5.2e-18 65.2 0.0 1e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 CAM39363.1 - 1.4e-06 29.2 0.1 3.1e-06 28.1 0.1 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein FTA4 PF13093.6 CAM39363.1 - 0.045 13.6 0.1 0.084 12.8 0.0 1.4 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Ldl_recept_a PF00057.18 CAM39363.1 - 8.8 6.6 26.6 0.36 11.1 4.2 3.7 4 0 0 4 4 4 0 Low-density lipoprotein receptor domain class A DUF2682 PF10909.8 CAM39365.1 - 0.11 13.0 0.0 0.13 12.8 0.0 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2682) AAA_6 PF12774.7 CAM39366.1 - 1.9e-152 507.0 0.0 2.3e-151 503.4 0.0 2.5 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CAM39366.1 - 6.6e-116 387.7 5.9 6.6e-116 387.7 5.9 3.8 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 CAM39366.1 - 6.1e-100 333.8 0.6 1.5e-99 332.5 0.0 2.1 2 0 0 2 2 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CAM39366.1 - 6.5e-95 317.9 0.1 2.8e-94 315.8 0.0 2.1 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 CAM39366.1 - 2.1e-85 285.3 0.5 2.1e-85 285.3 0.5 2.6 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 CAM39366.1 - 1.6e-53 180.9 0.0 6.8e-49 165.8 0.0 3.7 3 0 0 3 3 3 2 P-loop containing dynein motor region MT PF12777.7 CAM39366.1 - 1.7e-51 175.3 5.7 3.6e-51 174.2 5.7 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 CAM39366.1 - 8.2e-51 172.1 0.0 2.2e-50 170.7 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CAM39366.1 - 5.6e-40 136.2 0.0 5.4e-37 126.5 0.0 3.7 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 CAM39366.1 - 3.5e-24 85.4 0.0 2.4e-06 27.6 0.0 5.6 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 CAM39366.1 - 3.7e-18 65.8 0.0 1.1e-16 61.1 0.0 3.5 2 1 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CAM39366.1 - 8e-17 61.3 0.0 4e-16 59.1 0.0 2.3 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 CAM39366.1 - 6.6e-06 26.6 0.0 1.6 9.2 0.0 5.0 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 CAM39366.1 - 8.1e-06 25.4 0.7 0.0019 17.6 0.0 3.6 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_22 PF13401.6 CAM39366.1 - 9.7e-06 25.9 2.5 8.8 6.6 0.0 5.9 6 0 0 6 6 5 1 AAA domain AAA_16 PF13191.6 CAM39366.1 - 3e-05 24.5 15.2 2.5 8.4 0.0 7.4 6 2 0 7 7 7 2 AAA ATPase domain AAA_30 PF13604.6 CAM39366.1 - 0.0046 16.7 1.8 2.4 7.8 0.2 3.9 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 CAM39366.1 - 0.012 16.0 0.0 4.4 7.7 0.0 4.3 4 0 0 4 4 4 0 RNA helicase Trans_reg_C PF00486.28 CAM39366.1 - 0.093 12.8 0.1 0.37 10.9 0.1 2.1 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal Aldo_ket_red PF00248.21 CAM39367.1 - 5e-05 22.7 0.0 0.073 12.3 0.0 2.4 2 0 0 2 2 2 2 Aldo/keto reductase family Peptidase_M28 PF04389.17 CAM39368.1 - 9.8e-05 22.1 0.2 0.00023 20.9 0.1 1.6 2 0 0 2 2 2 1 Peptidase family M28 Arfaptin PF06456.13 CAM39368.1 - 0.039 13.5 1.0 0.07 12.7 0.2 1.8 2 0 0 2 2 2 0 Arfaptin-like domain Fer2 PF00111.27 CAM39369.1 - 1.8e-12 47.0 1.0 3e-12 46.3 1.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain RRM_1 PF00076.22 CAM39370.1 - 1.2e-07 31.5 0.0 2e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.10 CAM39370.1 - 0.095 13.0 0.3 0.2 11.9 0.0 1.7 2 0 0 2 2 2 0 CASC3/Barentsz eIF4AIII binding MBF1 PF08523.10 CAM39372.1 - 0.084 13.3 0.0 0.3 11.6 0.0 1.9 1 0 0 1 1 1 0 Multiprotein bridging factor 1 Ax_dynein_light PF10211.9 CAM39376.1 - 2.6e-42 144.9 2.0 4.5e-42 144.1 2.0 1.3 1 0 0 1 1 1 1 Axonemal dynein light chain LpqV PF17301.2 CAM39377.1 - 4.7 7.5 9.1 6.9 7.0 1.2 4.1 3 0 0 3 3 3 0 Putative lipoprotein LpqV PrpR_N PF06506.11 CAM39378.1 - 0.0083 15.7 0.1 0.051 13.1 0.1 2.1 2 0 0 2 2 2 1 Propionate catabolism activator TRAPP PF04051.16 CAM39378.1 - 0.038 13.7 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 Transport protein particle (TRAPP) component Smoa_sbd PF17885.1 CAM39378.1 - 0.14 12.3 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 Styrene monooxygenase A putative substrate binding domain PseudoU_synth_2 PF00849.22 CAM39380.1 - 3.1e-15 56.6 0.0 2.7e-07 30.8 0.0 3.8 2 2 0 2 2 2 2 RNA pseudouridylate synthase zf-RING_2 PF13639.6 CAM39381.2 - 1.9e-05 24.9 2.3 1.9e-05 24.9 2.3 3.0 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_3 PF13920.6 CAM39381.2 - 0.00018 21.3 2.3 0.00018 21.3 2.3 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CAM39381.2 - 0.0014 18.4 1.0 0.0014 18.4 1.0 2.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 CAM39381.2 - 0.0036 17.0 2.7 0.21 11.4 0.0 2.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 CAM39381.2 - 0.0047 16.8 2.1 0.0047 16.8 2.1 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CAM39381.2 - 0.0087 16.0 1.5 0.0087 16.0 1.5 3.2 3 0 0 3 3 3 1 zinc-RING finger domain Baculo_IE-1 PF05290.11 CAM39381.2 - 0.022 14.7 0.4 0.054 13.5 0.4 1.6 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) GOLGA2L5 PF15070.6 CAM39381.2 - 0.049 12.3 8.0 0.07 11.8 8.0 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 GIT1_C PF12205.8 CAM39381.2 - 2.1 8.5 4.9 3 8.0 2.4 2.3 1 1 1 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term Beta_helix PF13229.6 CAM39382.1 - 0.00047 20.0 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 2 Right handed beta helix region CENP-B_dimeris PF09026.10 CAM39382.1 - 3.3 8.2 16.1 0.18 12.2 5.9 2.8 3 0 0 3 3 3 0 Centromere protein B dimerisation domain DnaJ PF00226.31 CAM39384.1 - 2.4e-20 72.4 0.2 5e-20 71.4 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ-X PF14308.6 CAM39384.1 - 0.00032 20.2 0.1 0.0018 17.8 0.0 2.2 2 0 0 2 2 2 1 X-domain of DnaJ-containing Aldo_ket_red PF00248.21 CAM39385.1 - 2.5e-28 99.1 0.0 1.4e-24 86.9 0.0 2.5 1 1 1 2 2 2 2 Aldo/keto reductase family DUF3037 PF11236.8 CAM39385.1 - 0.06 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) LRR_4 PF12799.7 CAM39386.1 - 2.5e-11 43.6 2.4 9.3e-05 22.7 0.2 4.1 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM39386.1 - 6.6e-10 38.6 3.4 0.0052 16.5 5.1 4.4 3 1 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 CAM39386.1 - 0.00013 21.7 3.3 0.92 9.7 0.0 3.8 4 0 0 4 4 4 2 Leucine Rich repeat LRR_9 PF14580.6 CAM39386.1 - 0.00044 19.8 0.0 0.0011 18.5 0.0 1.6 2 0 0 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.33 CAM39386.1 - 0.021 15.3 11.1 26 5.9 0.5 5.8 6 0 0 6 6 6 0 Leucine Rich Repeat PTCB-BRCT PF12738.7 CAM39387.1 - 8e-05 22.5 0.4 2.1 8.4 0.0 3.8 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.26 CAM39387.1 - 0.00044 20.6 0.0 12 6.3 0.0 4.4 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain HSP70 PF00012.20 CAM39388.1 - 2.5e-244 812.0 4.9 2.8e-244 811.8 4.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CAM39388.1 - 5.6e-19 68.1 0.6 2.8e-17 62.5 0.1 2.3 2 0 0 2 2 2 2 MreB/Mbl protein BcrAD_BadFG PF01869.20 CAM39388.1 - 0.0031 17.0 1.1 2.3 7.7 0.0 3.0 3 0 0 3 3 3 2 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.18 CAM39388.1 - 0.0037 16.6 2.1 0.0084 15.4 0.3 2.5 4 0 0 4 4 4 1 Hydantoinase/oxoprolinase FtsA PF14450.6 CAM39388.1 - 0.011 16.2 2.0 5 7.6 0.1 3.5 3 2 0 3 3 3 0 Cell division protein FtsA Spore_GerAC PF05504.11 CAM39388.1 - 0.087 13.0 0.3 0.96 9.7 0.0 2.3 2 0 0 2 2 2 0 Spore germination B3/ GerAC like, C-terminal FYVE PF01363.21 CAM39390.2 - 2e-14 53.5 1.2 2e-14 53.5 1.2 2.6 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 CAM39390.2 - 7.2 6.9 9.1 0.093 12.9 1.0 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger DnaJ PF00226.31 CAM39391.1 - 5e-21 74.6 0.1 1.2e-20 73.3 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain DnaJ-X PF14308.6 CAM39391.1 - 1.1e-08 34.8 0.0 0.00042 19.8 0.1 2.4 2 0 0 2 2 2 2 X-domain of DnaJ-containing DUF1999 PF09390.10 CAM39391.1 - 0.048 13.3 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1999) Cupin_8 PF13621.6 CAM39393.1 - 5.2e-57 193.5 0.0 7.1e-56 189.7 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain HK97-gp10_like PF04883.12 CAM39395.2 - 7 7.7 7.4 23 6.1 1.5 2.3 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component DUF601 PF04642.12 CAM39397.1 - 0.092 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF601 DNA_ligase_OB_2 PF14743.6 CAM39398.1 - 4.1e-19 68.4 0.0 8.3e-19 67.4 0.0 1.6 1 0 0 1 1 1 1 DNA ligase OB-like domain DUF4379 PF14311.6 CAM39398.1 - 8.7e-14 51.6 2.3 2.7e-13 50.1 2.3 1.9 1 0 0 1 1 1 1 Probable Zinc-ribbon domain DNA_ligase_A_M PF01068.21 CAM39398.1 - 7e-11 42.1 0.0 1.2e-05 25.1 0.0 3.0 2 1 1 3 3 3 2 ATP dependent DNA ligase domain mRNA_cap_enzyme PF01331.19 CAM39398.1 - 0.0096 15.8 0.0 0.47 10.2 0.0 2.4 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain Vps36-NZF-N PF16988.5 CAM39398.1 - 0.021 14.2 0.2 0.045 13.2 0.2 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain PhnA_Zn_Ribbon PF08274.12 CAM39398.1 - 0.045 13.7 2.9 1.1 9.3 1.3 2.4 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Zn-ribbon_8 PF09723.10 CAM39398.1 - 0.085 13.0 1.0 0.2 11.8 1.0 1.6 1 0 0 1 1 1 0 Zinc ribbon domain zf-RRN7 PF11781.8 CAM39398.1 - 0.21 11.3 4.0 5.6 6.7 0.5 2.5 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-HYPF PF07503.12 CAM39398.1 - 0.25 11.2 1.9 0.47 10.3 1.9 1.5 1 0 0 1 1 1 0 HypF finger Rubredoxin_2 PF18073.1 CAM39398.1 - 2.7 7.8 7.1 4.8 7.0 1.2 2.5 2 0 0 2 2 2 0 Rubredoxin metal binding domain Zn_ribbon_SprT PF17283.2 CAM39398.1 - 7.9 6.5 9.2 8.2 6.4 6.6 2.4 2 1 1 3 3 3 0 SprT-like zinc ribbon domain DNA_ligase_A_M PF01068.21 CAM39399.1 - 3e-19 69.5 0.0 1.1e-18 67.6 0.0 1.9 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_OB_2 PF14743.6 CAM39399.1 - 8.3e-15 54.6 0.0 1.6e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 DNA ligase OB-like domain mRNA_cap_enzyme PF01331.19 CAM39399.1 - 0.00037 20.4 0.0 1.1 9.0 0.0 3.2 2 2 0 2 2 2 2 mRNA capping enzyme, catalytic domain DUF4379 PF14311.6 CAM39399.1 - 0.0027 18.0 7.4 0.0064 16.8 7.4 1.7 1 0 0 1 1 1 1 Probable Zinc-ribbon domain Zn-ribbon_8 PF09723.10 CAM39399.1 - 0.0036 17.4 0.7 0.011 15.8 0.7 1.9 1 0 0 1 1 1 1 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 CAM39399.1 - 0.99 9.4 3.9 2.5 8.1 0.1 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Thioredoxin PF00085.20 CAM39400.1 - 0.0098 15.9 0.1 0.3 11.1 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin Peptidase_M16 PF00675.20 CAM39400.1 - 0.065 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) MMR_HSR1 PF01926.23 CAM39401.1 - 5.3e-15 55.5 0.0 3.1e-13 49.8 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CAM39401.1 - 2.2e-06 27.3 0.0 0.00032 20.3 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CAM39401.1 - 0.00016 21.6 0.0 0.0072 16.2 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 CAM39401.1 - 0.002 17.7 0.0 2.8 7.5 0.0 3.0 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CAM39401.1 - 0.0042 17.2 1.1 0.1 12.7 0.2 2.7 1 1 1 2 2 2 1 Dynamin family Rib_recp_KP_reg PF05104.12 CAM39401.1 - 6.8 7.7 12.9 1.6 9.8 5.3 2.8 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region Prefoldin PF02996.17 CAM39402.1 - 8.9e-26 90.2 1.9 1.2e-25 89.8 1.3 1.5 1 1 0 1 1 1 1 Prefoldin subunit End3 PF12761.7 CAM39402.1 - 0.031 14.5 2.9 1.4 9.0 0.8 2.3 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 TPR_12 PF13424.6 CAM39402.1 - 0.092 13.0 1.7 0.57 10.5 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat YabA PF06156.13 CAM39402.1 - 0.17 12.5 4.7 14 6.4 3.5 2.3 2 0 0 2 2 2 0 Initiation control protein YabA WD40 PF00400.32 CAM39404.2 - 5.5e-16 58.7 12.6 0.00046 20.9 0.2 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat WWE PF02825.20 CAM39404.2 - 9.1e-12 45.4 0.7 3.1e-11 43.7 0.7 2.0 1 1 0 1 1 1 1 WWE domain DnaJ PF00226.31 CAM39405.1 - 4.6e-18 65.1 0.4 4.6e-18 65.1 0.4 1.7 2 0 0 2 2 2 1 DnaJ domain DUF3180 PF11377.8 CAM39405.1 - 0.027 14.6 0.3 0.027 14.6 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3180) MORN PF02493.20 CAM39406.2 - 3.4e-41 136.7 127.4 0.00012 21.8 0.5 24.1 26 0 0 26 26 26 18 MORN repeat FYVE PF01363.21 CAM39406.2 - 4.9e-26 90.6 14.7 1.5e-18 66.6 4.8 2.7 2 0 0 2 2 2 2 FYVE zinc finger FYVE_2 PF02318.16 CAM39406.2 - 2.6 8.3 13.1 3.7 7.8 3.6 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger Cyt-b5 PF00173.28 CAM39407.2 - 5.1e-18 65.0 0.0 9.8e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ESR1_C PF12743.7 CAM39408.2 - 0.51 10.1 3.9 0.26 11.1 0.2 2.5 2 0 0 2 2 2 0 Oestrogen-type nuclear receptor final C-terminal Ribosomal_L29 PF00831.23 CAM39409.1 - 0.056 13.4 0.6 0.16 11.9 0.6 1.8 1 0 0 1 1 1 0 Ribosomal L29 protein CYYR1 PF10873.8 CAM39410.1 - 0.011 16.2 0.8 0.024 15.1 0.0 2.0 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 YniB PF14002.6 CAM39410.1 - 0.12 12.2 0.0 0.34 10.7 0.0 1.8 1 0 0 1 1 1 0 YniB-like protein Prenyltrans PF00432.21 CAM39411.1 - 2.6e-22 78.3 13.6 5.2e-05 22.9 0.2 5.9 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 CAM39411.1 - 0.096 11.8 0.0 0.24 10.5 0.0 1.6 1 0 0 1 1 1 0 Squalene-hopene cyclase N-terminal domain COG7 PF10191.9 CAM39412.1 - 2.6e-09 35.9 13.8 0.00072 17.9 1.7 5.1 5 0 0 5 5 5 5 Golgi complex component 7 (COG7) FEZ PF07763.13 CAM39412.1 - 0.051 13.3 2.8 0.67 9.7 0.0 2.8 2 1 0 2 2 2 0 FEZ-like protein DUF4378 PF14309.6 CAM39412.1 - 0.089 13.2 1.8 2.1 8.7 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4378) zf-ZPR1 PF03367.13 CAM39412.1 - 0.12 12.2 1.9 12 5.8 0.0 2.7 2 0 0 2 2 2 0 ZPR1 zinc-finger domain PhoD PF09423.10 CAM39413.1 - 0.0015 17.7 0.0 0.034 13.2 0.0 2.4 2 1 0 2 2 2 1 PhoD-like phosphatase Herpes_UL73 PF03554.13 CAM39413.1 - 0.56 10.2 0.0 0.56 10.2 0.0 2.1 2 0 0 2 2 2 0 UL73 viral envelope glycoprotein DUF2721 PF11026.8 CAM39413.1 - 0.81 9.6 5.1 0.35 10.8 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Abhydrolase_6 PF12697.7 CAM39416.1 - 1e-11 45.9 2.0 1.6e-11 45.2 2.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CAM39416.1 - 5.3e-05 22.6 0.6 0.076 12.3 0.0 4.1 3 1 1 4 4 4 1 Serine aminopeptidase, S33 DUF915 PF06028.11 CAM39416.1 - 0.0025 17.2 0.0 0.0088 15.4 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.20 CAM39416.1 - 0.012 15.3 1.5 0.25 11.0 0.7 2.8 2 1 0 2 2 2 0 alpha/beta hydrolase fold RRM_1 PF00076.22 CAM39417.1 - 4.1e-16 58.6 0.0 6.6e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CAM39417.1 - 1.6e-05 24.5 0.0 2.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAM39417.1 - 0.0031 17.6 0.0 0.0078 16.3 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif PHM7_cyt PF14703.6 CAM39417.1 - 0.075 13.3 0.1 1.7 8.8 0.1 2.2 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Glutaredoxin PF00462.24 CAM39418.1 - 6e-07 29.6 0.0 1.5e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 CAM39418.1 - 5.5e-05 23.5 0.0 0.00019 21.8 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CAM39418.1 - 0.054 13.8 0.0 0.18 12.1 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CAM39418.1 - 0.086 13.2 0.0 0.34 11.3 0.0 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF836 PF05768.14 CAM39418.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) GST_C_4 PF14834.6 CAM39418.1 - 0.16 12.4 0.0 0.28 11.6 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain 3HCDH_N PF02737.18 CAM39419.1 - 8.2e-51 172.4 3.8 1.4e-50 171.6 3.8 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 CAM39419.1 - 5.5e-33 113.5 0.1 2.2e-22 79.4 0.0 3.1 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_1 PF00378.20 CAM39419.1 - 5.7e-31 107.7 2.3 6e-31 107.7 0.2 2.1 2 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CAM39419.1 - 1.8e-21 77.0 0.2 5.9e-21 75.3 0.1 1.9 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase NAD_binding_2 PF03446.15 CAM39419.1 - 0.00018 21.7 2.0 0.00027 21.1 0.6 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 CAM39419.1 - 0.0061 16.6 2.3 0.66 10.0 0.5 2.7 2 1 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 CAM39419.1 - 0.044 14.0 1.2 0.16 12.2 0.6 2.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 CAM39419.1 - 0.31 10.3 3.9 0.9 8.8 2.1 2.1 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.17 CAM39419.1 - 0.32 11.6 3.6 0.92 10.1 2.0 2.5 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent SNF2_N PF00176.23 CAM39420.1 - 7.2e-30 103.9 0.3 2.7e-20 72.4 0.0 3.2 3 0 0 3 3 3 3 SNF2 family N-terminal domain zf-RING_2 PF13639.6 CAM39420.1 - 7.8e-07 29.3 7.6 1.7e-06 28.2 4.8 3.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 CAM39420.1 - 9.6e-07 28.7 1.6 9.6e-07 28.7 1.6 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CAM39420.1 - 1.2e-06 28.3 5.5 4.1e-06 26.6 5.5 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CAM39420.1 - 3.3e-06 26.9 5.9 3.3e-06 26.9 5.9 2.9 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 CAM39420.1 - 4.6e-06 26.9 0.0 9.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 CAM39420.1 - 3e-05 23.8 6.5 3e-05 23.8 6.5 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CAM39420.1 - 4.3e-05 23.4 4.7 4.3e-05 23.4 4.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CAM39420.1 - 0.0011 19.1 5.7 0.0011 19.1 5.7 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CAM39420.1 - 0.0041 17.0 4.2 0.0041 17.0 4.2 2.5 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 CAM39420.1 - 0.53 10.1 4.2 1.5 8.6 4.2 1.9 1 0 0 1 1 1 0 RING-like zinc finger zf-ANAPC11 PF12861.7 CAM39420.1 - 1.2 9.2 4.0 1.3 9.1 0.9 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 CAM39420.1 - 4.9 7.4 7.1 1.8 8.8 3.5 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 Peptidase_M3 PF01432.20 CAM39421.1 - 5.8e-115 385.1 0.0 3e-114 382.8 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M3 Peptidase_M50B PF13398.6 CAM39421.1 - 0.034 13.8 0.5 0.065 12.9 0.5 1.4 1 0 0 1 1 1 0 Peptidase M50B-like PQQ_2 PF13360.6 CAM39422.2 - 0.00036 20.2 0.1 0.00082 19.0 0.1 1.5 1 0 0 1 1 1 1 PQQ-like domain WD40 PF00400.32 CAM39423.1 - 3.7e-13 49.7 3.1 0.015 16.1 0.0 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat EF-hand_1 PF00036.32 CAM39423.1 - 5.6e-05 22.4 0.0 0.0012 18.2 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CAM39423.1 - 0.00048 19.8 0.1 0.042 13.8 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain ANAPC4_WD40 PF12894.7 CAM39423.1 - 0.00068 19.9 0.1 1.2 9.5 0.0 3.4 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_7 PF13499.6 CAM39423.1 - 0.00085 19.7 1.0 0.032 14.7 0.1 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CAM39423.1 - 0.0014 18.4 0.0 0.007 16.2 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 CAM39423.1 - 0.06 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 EF hand Gmad1 PF10647.9 CAM39423.1 - 0.093 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain PPK2 PF03976.14 CAM39423.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) U-box PF04564.15 CAM39424.1 - 0.00098 19.3 0.0 0.0022 18.1 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 CAM39424.1 - 0.042 14.0 0.1 0.11 12.7 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Pro_dh PF01619.18 CAM39425.1 - 9.2e-64 215.8 0.4 1.6e-63 215.0 0.4 1.3 1 0 0 1 1 1 1 Proline dehydrogenase AP_endonuc_2 PF01261.24 CAM39425.1 - 0.0037 16.7 0.0 0.094 12.1 0.0 2.4 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel EF-hand_7 PF13499.6 CAM39425.1 - 0.02 15.3 0.0 0.046 14.2 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair CTP_transf_1 PF01148.20 CAM39426.1 - 8.8e-63 212.5 18.3 1.2e-62 212.1 18.3 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Ribosomal_S28e PF01200.18 CAM39427.1 - 2e-29 101.4 0.8 2.4e-29 101.1 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e Ribosomal_S28e PF01200.18 CAM39428.1 - 2e-29 101.4 0.8 2.4e-29 101.1 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e MIT PF04212.18 CAM39429.2 - 3.8e-05 23.7 0.2 7.3e-05 22.8 0.2 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain FliS PF02561.14 CAM39429.2 - 0.057 13.7 0.4 0.27 11.5 0.0 2.2 2 1 0 2 2 2 0 Flagellar protein FliS Spo0A_C PF08769.11 CAM39429.2 - 0.091 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal LRR_6 PF13516.6 CAM39430.1 - 1.9e-06 27.4 8.1 1.2 9.3 0.1 6.3 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.33 CAM39430.1 - 0.048 14.2 11.7 10 7.1 0.0 5.9 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_4 PF12799.7 CAM39430.1 - 1.5 9.4 11.6 28 5.3 1.1 5.1 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) LpxC PF03331.13 CAM39431.1 - 0.15 11.6 0.1 0.19 11.2 0.1 1.1 1 0 0 1 1 1 0 UDP-3-O-acyl N-acetylglycosamine deacetylase GATase_6 PF13522.6 CAM39432.2 - 0.074 13.3 0.1 0.088 13.0 0.1 1.1 1 0 0 1 1 1 0 Glutamine amidotransferase domain NuA4 PF09340.10 CAM39433.1 - 1.8e-08 34.1 0.0 2.8e-06 27.1 0.0 2.4 2 0 0 2 2 2 2 Histone acetyltransferase subunit NuA4 Cnd1 PF12717.7 CAM39434.2 - 0.014 15.4 0.0 0.04 13.9 0.0 1.8 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CAM39434.2 - 0.034 14.4 0.4 8.8 6.9 0.0 4.4 3 0 0 3 3 3 0 HEAT repeat UvrC_HhH_N PF08459.11 CAM39434.2 - 0.12 12.2 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal DUF3123 PF11321.8 CAM39434.2 - 1.7 9.4 4.6 1.4 9.6 0.6 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) DUF5327 PF17261.2 CAM39434.2 - 2.4 8.9 6.7 4.1 8.2 2.8 3.1 2 0 0 2 2 2 0 Family of unknown function (DUF5327) DNA_binding_1 PF01035.20 CAM39435.1 - 2.7e-19 69.0 0.0 5.4e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain SSI PF00720.17 CAM39435.1 - 0.0052 16.7 0.4 0.01 15.8 0.4 1.5 1 0 0 1 1 1 1 Subtilisin inhibitor-like AbrB PF05145.12 CAM39435.1 - 0.028 13.4 0.5 0.042 12.8 0.5 1.2 1 0 0 1 1 1 0 Transition state regulatory protein AbrB zf-C2H2_4 PF13894.6 CAM39436.2 - 1.4e-07 31.8 30.2 0.00034 21.2 2.9 5.2 5 0 0 5 5 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CAM39436.2 - 3.8e-07 30.3 2.4 3.8e-07 30.3 2.4 6.7 7 0 0 7 7 7 1 Zinc-finger double domain zf-Di19 PF05605.12 CAM39436.2 - 4.8e-05 23.6 12.6 0.024 14.9 0.2 4.0 4 0 0 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 CAM39436.2 - 8.6e-05 22.8 42.2 0.00022 21.5 3.4 6.1 6 0 0 6 6 5 3 Zinc finger, C2H2 type PhnA_Zn_Ribbon PF08274.12 CAM39436.2 - 0.0093 15.9 3.1 0.45 10.5 0.1 3.1 3 0 0 3 3 3 1 PhnA Zinc-Ribbon zf-H2C2_5 PF13909.6 CAM39436.2 - 0.024 14.4 0.7 0.024 14.4 0.7 4.9 5 0 0 5 5 4 0 C2H2-type zinc-finger domain LIM PF00412.22 CAM39436.2 - 0.034 14.4 3.5 1.5 9.1 0.2 3.3 3 0 0 3 3 3 0 LIM domain zf-C2H2_3rep PF18868.1 CAM39436.2 - 0.036 14.8 2.1 9.6 6.9 0.2 3.6 4 0 0 4 4 4 0 Zinc finger C2H2-type, 3 repeats Ima1_N PF09779.9 CAM39436.2 - 0.22 12.4 2.0 1.8 9.5 0.1 3.1 3 0 0 3 3 3 0 Ima1 N-terminal domain zinc_ribbon_9 PF14369.6 CAM39436.2 - 1.1 9.5 7.7 18 5.7 0.1 4.0 4 0 0 4 4 3 0 zinc-ribbon zf-C2H2_2 PF12756.7 CAM39436.2 - 1.2 9.6 4.7 8.9 6.7 0.1 3.5 3 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-CHY PF05495.12 CAM39436.2 - 1.3 9.5 8.7 7.2 7.2 0.1 3.8 4 0 0 4 4 4 0 CHY zinc finger zf-BED PF02892.15 CAM39436.2 - 1.9 8.6 13.2 4 7.5 0.5 3.7 3 1 1 4 4 4 0 BED zinc finger zf-FCS PF06467.14 CAM39436.2 - 2.2 8.3 6.6 0.51 10.3 0.1 3.0 4 0 0 4 4 4 0 MYM-type Zinc finger with FCS sequence motif zf-TRAF PF02176.18 CAM39436.2 - 2.8 8.7 6.0 20 6.0 0.2 2.9 2 0 0 2 2 2 0 TRAF-type zinc finger zf-C2H2_jaz PF12171.8 CAM39436.2 - 4.8 7.6 7.4 21 5.5 0.1 4.0 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-AN1 PF01428.16 CAM39436.2 - 4.9 7.4 7.0 24 5.2 0.2 4.0 4 0 0 4 4 4 0 AN1-like Zinc finger Zn_Tnp_IS1595 PF12760.7 CAM39436.2 - 6.1 6.9 14.7 40 4.3 0.1 4.0 3 1 1 4 4 4 0 Transposase zinc-ribbon domain DUF789 PF05623.12 CAM39437.2 - 1e-09 38.5 0.0 1.2e-08 35.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF789) Methyltransf_31 PF13847.6 CAM39439.1 - 0.23 11.3 0.1 0.42 10.4 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain ELMO_CED12 PF04727.13 CAM39440.1 - 1.6e-41 142.3 0.0 2.8e-41 141.6 0.0 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3038 PF11237.8 CAM39440.1 - 0.19 11.8 2.1 0.34 10.9 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3038) LRR_4 PF12799.7 CAM39442.1 - 0.018 15.5 0.3 34 5.0 0.0 3.8 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CAM39442.1 - 0.047 13.7 13.0 1.8 8.8 0.2 5.5 6 0 0 6 6 6 0 Leucine Rich repeat DUF4460 PF14687.6 CAM39443.1 - 2.1e-08 34.2 0.2 4.6e-08 33.1 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4460) DUF4461 PF14688.6 CAM39443.1 - 0.036 13.9 4.3 0.056 13.2 1.4 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4461) DUF3741 PF12552.8 CAM39443.1 - 0.068 13.1 0.0 0.91 9.5 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3741) DUF2959 PF11172.8 CAM39443.1 - 0.26 11.4 4.9 6.8 6.8 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2959) Sedlin_N PF04628.13 CAM39444.1 - 0.014 15.5 0.0 0.029 14.5 0.0 1.5 1 1 0 1 1 1 0 Sedlin, N-terminal conserved region HEAT_2 PF13646.6 CAM39446.1 - 1.1e-25 89.8 9.6 8.9e-16 58.1 0.8 3.3 2 1 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.16 CAM39446.1 - 2.7e-17 61.6 13.8 0.0011 19.5 0.1 6.4 7 0 0 7 7 7 4 PBS lyase HEAT-like repeat HEAT PF02985.22 CAM39446.1 - 4.4e-07 29.6 4.5 0.017 15.3 0.1 5.3 6 1 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 CAM39446.1 - 0.00062 20.2 5.4 0.032 14.8 0.6 4.5 3 2 2 5 5 5 1 HEAT-like repeat DMRT-like PF15791.5 CAM39446.1 - 0.024 15.0 4.9 0.23 11.9 0.8 3.0 2 1 0 2 2 2 0 Doublesex-and mab-3-related transcription factor C1 and C2 IFRD PF05004.13 CAM39446.1 - 0.025 13.7 0.2 0.3 10.1 0.1 2.2 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) DUF5463 PF17551.2 CAM39446.1 - 0.16 11.9 0.2 0.32 11.0 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5463) TRAM_LAG1_CLN8 PF03798.16 CAM39447.1 - 7.1e-17 61.8 15.8 7.1e-17 61.8 15.8 1.5 2 0 0 2 2 2 1 TLC domain Cas1_AcylT PF07779.12 CAM39447.1 - 0.0017 17.4 2.5 0.0017 17.4 2.5 1.8 1 1 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p 4HBT_2 PF13279.6 CAM39448.2 - 6e-06 26.8 0.1 9.1e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 CAM39448.2 - 1.6e-05 25.1 0.1 2.9e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 CAM39448.2 - 0.049 12.9 0.1 0.078 12.2 0.1 1.3 1 1 0 1 1 1 0 Acyl-ACP thioesterase MarR_2 PF12802.7 CAM39449.2 - 0.016 15.1 0.0 40 4.2 0.0 4.6 5 0 0 5 5 5 0 MarR family MT PF12777.7 CAM39449.2 - 0.025 13.6 0.0 0.048 12.7 0.0 1.4 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor NdhS PF11623.8 CAM39449.2 - 2.3 7.9 4.6 50 3.7 0.0 5.5 7 0 0 7 7 7 0 NAD(P)H dehydrogenase subunit S SCO1-SenC PF02630.14 CAM39451.1 - 3.8e-44 149.8 0.0 5.6e-44 149.3 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 CAM39451.1 - 0.00068 19.6 0.0 0.0013 18.7 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 CAM39451.1 - 0.0045 17.3 0.0 0.009 16.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Methyltransf_23 PF13489.6 CAM39454.1 - 3.9e-14 52.8 0.0 6.4e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAM39454.1 - 8.5e-13 48.4 0.0 8.6e-06 25.6 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 CAM39454.1 - 3e-10 40.6 0.0 0.0011 19.5 0.0 2.5 1 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 CAM39454.1 - 1.2e-09 38.7 0.0 1.4e-08 35.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAM39454.1 - 1.8e-09 38.2 0.1 2.3e-05 25.0 0.0 3.0 1 1 1 2 2 2 2 Methyltransferase domain DREV PF05219.12 CAM39454.1 - 0.0016 17.6 0.0 0.0051 15.9 0.0 1.7 1 1 1 2 2 2 1 DREV methyltransferase CMAS PF02353.20 CAM39454.1 - 0.0097 15.2 0.1 0.036 13.4 0.0 1.8 1 1 1 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_3 PF01596.17 CAM39454.1 - 0.095 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase PHD PF00628.29 CAM39455.1 - 0.0041 17.0 7.3 0.008 16.1 7.3 1.5 1 0 0 1 1 1 1 PHD-finger Zn_ribbon_17 PF17120.5 CAM39455.1 - 0.02 14.5 4.3 0.041 13.5 4.3 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF4428 PF14471.6 CAM39455.1 - 0.14 12.1 0.4 23 5.0 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) ATG22 PF11700.8 CAM39457.2 - 0.04 12.6 0.1 0.075 11.7 0.1 1.4 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like HEAT PF02985.22 CAM39457.2 - 0.17 12.2 3.4 0.54 10.7 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat PQ-loop PF04193.14 CAM39458.1 - 6e-19 67.6 0.2 1.7e-12 46.9 0.0 2.7 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 CAM39458.1 - 0.012 16.5 2.2 0.012 16.5 2.2 2.3 2 0 0 2 2 2 0 ER lumen protein retaining receptor UL42 PF17638.2 CAM39458.1 - 0.16 11.9 0.1 0.16 11.9 0.1 2.6 3 0 0 3 3 3 0 HCMV UL42 Pkinase PF00069.25 CAM39460.1 - 5.8e-13 48.8 0.0 1.4e-09 37.7 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM39460.1 - 3.5e-07 29.8 0.5 0.0022 17.3 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Peptidase_C48 PF02902.19 CAM39461.2 - 2.2e-14 53.8 0.0 1.2e-05 25.3 0.0 2.9 2 1 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain DUF4050 PF13259.6 CAM39462.1 - 0.15 12.3 2.0 0.56 10.5 0.1 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF4050) Metallophos PF00149.28 CAM39464.2 - 6.7e-15 56.1 0.0 9.3e-13 49.1 0.0 3.2 3 0 0 3 3 3 1 Calcineurin-like phosphoesterase CitT PF12431.8 CAM39464.2 - 0.12 12.8 0.1 0.35 11.3 0.1 1.9 1 0 0 1 1 1 0 Transcriptional regulator Pkinase PF00069.25 CAM39465.1 - 3.7e-32 111.8 0.0 1.1e-15 57.8 0.0 3.6 4 0 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM39465.1 - 9.2e-06 25.1 0.0 0.00024 20.5 0.0 2.8 4 0 0 4 4 4 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CAM39465.1 - 0.0018 17.3 0.0 0.003 16.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CAM39465.1 - 0.074 11.8 0.4 0.24 10.1 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase CIAPIN1 PF05093.13 CAM39465.1 - 0.39 11.3 1.6 0.9 10.1 0.1 2.5 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Pkinase PF00069.25 CAM39466.2 - 6.7e-08 32.2 0.0 5.4e-06 26.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Limkain-b1 PF11608.8 CAM39467.1 - 0.12 12.5 0.0 0.35 11.0 0.0 1.8 1 1 0 1 1 1 0 Limkain b1 Pet191_N PF10203.9 CAM39468.1 - 0.012 15.9 4.2 0.17 12.2 0.6 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.13 CAM39468.1 - 0.07 13.3 2.3 0.07 13.3 2.3 2.2 3 0 0 3 3 3 0 CHCH domain FtsJ PF01728.19 CAM39469.1 - 2.6e-05 24.4 0.0 0.00011 22.4 0.0 1.9 1 1 0 1 1 1 1 FtsJ-like methyltransferase Arf PF00025.21 CAM39473.1 - 1.5e-22 79.9 0.6 4.1e-13 49.2 0.4 4.4 3 1 0 3 3 3 2 ADP-ribosylation factor family G-alpha PF00503.20 CAM39473.1 - 2e-10 40.4 0.0 2e-05 23.9 0.1 2.1 2 0 0 2 2 2 2 G-protein alpha subunit AAA_29 PF13555.6 CAM39473.1 - 0.0001 22.0 0.0 0.0011 18.7 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain Roc PF08477.13 CAM39473.1 - 0.00018 21.7 0.0 0.66 10.2 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 CAM39473.1 - 0.0002 20.9 0.0 0.29 10.6 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CAM39473.1 - 0.00022 20.7 0.0 0.19 11.1 0.0 2.4 2 1 0 2 2 2 2 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CAM39473.1 - 0.00096 19.2 0.0 0.051 13.7 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 CAM39473.1 - 0.0014 19.2 0.0 0.0051 17.3 0.0 2.0 2 0 0 2 2 2 1 ABC transporter Ras PF00071.22 CAM39473.1 - 0.0051 16.4 0.0 6.1 6.4 0.0 3.8 2 1 0 2 2 2 1 Ras family Dynamin_N PF00350.23 CAM39473.1 - 0.0086 16.2 0.8 0.019 15.0 0.8 1.8 1 1 0 1 1 1 1 Dynamin family AAA_28 PF13521.6 CAM39473.1 - 0.016 15.4 0.2 0.041 14.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CAM39473.1 - 0.022 15.2 2.0 0.072 13.5 2.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 CAM39473.1 - 0.067 12.5 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Septin AAA_23 PF13476.6 CAM39473.1 - 0.099 13.1 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 CAM39473.1 - 0.1 12.0 0.2 0.24 10.8 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein RsgA_GTPase PF03193.16 CAM39473.1 - 0.13 12.1 0.0 14 5.5 0.0 3.0 3 0 0 3 3 3 0 RsgA GTPase AAA_16 PF13191.6 CAM39475.1 - 1.4e-06 28.8 1.0 3e-05 24.4 0.2 3.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CAM39475.1 - 7.1e-05 23.1 0.1 0.66 10.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain Kinesin PF00225.23 CAM39475.1 - 0.02 13.8 0.0 0.042 12.8 0.0 1.4 1 0 0 1 1 1 0 Kinesin motor domain CoaE PF01121.20 CAM39475.1 - 0.058 13.1 0.0 0.18 11.4 0.0 1.8 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_19 PF13245.6 CAM39475.1 - 0.079 13.3 0.0 0.47 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CAM39475.1 - 0.18 11.3 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Ribosomal_L38e PF01781.18 CAM39476.1 - 6.4e-29 99.9 4.3 7.6e-29 99.6 4.3 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family GDP_Man_Dehyd PF16363.5 CAM39477.1 - 1.3e-65 222.0 0.1 5.4e-60 203.5 0.0 2.0 1 1 1 2 2 2 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CAM39477.1 - 2.6e-51 174.4 0.2 6.2e-51 173.2 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 CAM39477.1 - 9.2e-23 80.7 0.1 2.3e-19 69.6 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 CAM39477.1 - 1.1e-19 70.5 0.0 2.6e-14 52.9 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 CAM39477.1 - 2.4e-19 69.6 0.0 4.2e-13 49.1 0.0 3.0 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 CAM39477.1 - 3.6e-19 68.9 0.4 2.8e-18 66.0 0.3 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain Aminotran_5 PF00266.19 CAM39478.1 - 3.3e-13 49.3 0.0 4.8e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 CAM39478.1 - 0.0012 17.5 0.0 0.0018 16.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 CAM39478.1 - 0.014 14.7 0.2 0.049 12.9 0.0 1.8 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Sec1 PF00995.23 CAM39480.1 - 2.4e-87 294.5 0.0 2.8e-87 294.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family MRP-S34 PF16053.5 CAM39481.1 - 2.2e-05 24.1 0.0 3.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 CN_hydrolase PF00795.22 CAM39482.1 - 4e-50 170.6 0.0 4.6e-50 170.4 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Esterase PF00756.20 CAM39483.1 - 0.12 12.0 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Putative esterase Baculo_PEP_C PF04513.12 CAM39484.1 - 2.3 8.3 45.7 3.6 7.6 6.2 9.7 8 2 1 9 9 9 0 Baculovirus polyhedron envelope protein, PEP, C terminus AMH_N PF04709.12 CAM39485.1 - 0.0016 17.5 0.3 0.0016 17.4 0.3 1.1 1 0 0 1 1 1 1 Anti-Mullerian hormone, N terminal region WD40 PF00400.32 CAM39487.1 - 1.9e-08 34.8 11.3 0.044 14.7 1.1 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF4533 PF15047.6 CAM39487.1 - 0.018 14.6 1.1 0.018 14.6 1.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4533) Zip PF02535.22 CAM39487.1 - 0.026 13.8 1.6 0.049 12.8 1.6 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter NOA36 PF06524.12 CAM39487.1 - 0.19 11.0 12.7 0.32 10.3 12.7 1.3 1 0 0 1 1 1 0 NOA36 protein BUD22 PF09073.10 CAM39487.1 - 0.78 9.0 24.5 0.014 14.7 17.0 1.7 2 0 0 2 2 2 0 BUD22 MutS_III PF05192.18 CAM39487.1 - 0.89 9.7 6.1 1.7 8.8 6.1 1.4 1 0 0 1 1 1 0 MutS domain III GEMIN8 PF15348.6 CAM39487.1 - 0.99 9.7 19.4 0.04 14.2 13.3 1.7 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 RNA_pol_3_Rpc31 PF11705.8 CAM39487.1 - 2.6 8.3 21.7 6.4 7.0 21.7 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 ALMT PF11744.8 CAM39487.1 - 4.7 5.9 11.3 8.5 5.1 11.3 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Ribosomal_L29 PF00831.23 CAM39488.1 - 5.8e-19 67.8 2.5 5.8e-19 67.8 2.5 2.2 2 1 0 2 2 2 1 Ribosomal L29 protein MRP-L47 PF06984.13 CAM39488.1 - 0.041 14.0 0.6 0.041 14.0 0.6 1.8 2 1 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) CCDC-167 PF15188.6 CAM39488.1 - 0.63 10.4 8.2 3.6 8.0 1.1 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF724 PF05266.14 CAM39488.1 - 1.2 9.0 5.2 1.8 8.4 5.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Ribosomal_L29 PF00831.23 CAM39489.1 - 5.8e-19 67.8 2.5 5.8e-19 67.8 2.5 2.2 2 1 0 2 2 2 1 Ribosomal L29 protein MRP-L47 PF06984.13 CAM39489.1 - 0.041 14.0 0.6 0.041 14.0 0.6 1.8 2 1 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) CCDC-167 PF15188.6 CAM39489.1 - 0.63 10.4 8.2 3.6 8.0 1.1 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF724 PF05266.14 CAM39489.1 - 1.2 9.0 5.2 1.8 8.4 5.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Sec1 PF00995.23 CAM39491.1 - 7.7e-89 299.5 0.0 8.9e-89 299.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family HECT PF00632.25 CAM39492.2 - 2.5e-34 119.2 0.0 5.3e-34 118.1 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 CAM39492.2 - 1.2e-12 47.9 0.0 1.2e-09 38.3 0.0 2.9 3 0 0 3 3 3 2 SPRY domain zf-RanBP PF00641.18 CAM39492.2 - 1.2e-06 27.7 15.0 4.3e-05 22.7 2.7 2.8 1 1 1 2 2 2 2 Zn-finger in Ran binding protein and others HEAT PF02985.22 CAM39492.2 - 0.3 11.5 3.0 25 5.5 0.7 3.6 2 0 0 2 2 2 0 HEAT repeat fn3 PF00041.21 CAM39493.2 - 7e-89 292.3 55.9 1.8e-05 25.0 0.4 37.4 41 2 0 41 41 41 21 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CAM39493.2 - 6.9e-38 129.1 51.4 0.0035 17.9 1.3 27.9 29 1 0 29 29 29 8 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 CAM39493.2 - 2.1e-17 63.4 1.0 2 8.8 0.0 14.6 17 0 0 17 17 17 3 Interferon-alpha/beta receptor, fibronectin type III Glyco_hydro_36C PF16874.5 CAM39493.2 - 6.1e-06 26.6 0.0 20 5.8 0.0 9.4 11 1 1 12 12 12 1 Glycosyl hydrolase family 36 C-terminal domain Arylsulfotran_N PF17425.2 CAM39493.2 - 0.00027 20.9 0.0 1.3 9.1 0.0 6.2 7 0 0 7 7 7 1 Arylsulfotransferase Ig-like domain fn3_4 PF16794.5 CAM39493.2 - 0.15 12.0 0.0 50 3.9 0.0 4.9 4 0 0 4 4 4 0 Fibronectin-III type domain zf-primase PF09329.11 CAM39494.1 - 8.9e-10 38.2 0.4 1.9e-09 37.2 0.4 1.6 1 0 0 1 1 1 1 Primase zinc finger Mcm10 PF09332.11 CAM39494.1 - 5.4e-08 32.7 4.5 1.1e-07 31.7 4.5 1.4 1 0 0 1 1 1 1 Mcm10 replication factor Tim17 PF02466.19 CAM39495.1 - 3.8e-10 40.1 1.6 2e-09 37.8 0.7 2.0 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family SOAR PF16533.5 CAM39496.1 - 0.00036 20.4 5.3 0.0032 17.4 0.3 2.9 2 0 0 2 2 2 2 STIM1 Orai1-activating region PARP_reg PF02877.14 CAM39496.1 - 0.0063 16.6 0.3 0.12 12.5 0.1 2.5 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase, regulatory domain USP8_interact PF08941.10 CAM39496.1 - 0.048 13.5 0.3 0.048 13.5 0.3 2.2 2 0 0 2 2 2 0 USP8 interacting BTB PF00651.31 CAM39497.1 - 1.7e-12 47.5 0.0 4e-05 23.8 0.0 2.9 2 1 0 2 2 2 2 BTB/POZ domain MATH PF00917.26 CAM39497.1 - 0.00032 20.8 0.0 0.00057 20.0 0.0 1.3 1 0 0 1 1 1 1 MATH domain JAB PF01398.21 CAM39498.2 - 3.5e-10 39.9 0.1 7.1e-10 38.9 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 CAM39498.2 - 6.1e-06 26.0 0.1 1.4e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Pkinase PF00069.25 CAM39499.2 - 9.3e-39 133.4 0.0 1.2e-38 133.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM39499.2 - 1.6e-25 89.9 0.0 2.4e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CAM39499.2 - 0.00083 18.8 0.3 0.0016 17.8 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CAM39499.2 - 0.0054 16.1 0.0 0.013 14.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like UPF0492 PF15744.5 CAM39500.1 - 0.013 14.7 3.0 0.017 14.4 3.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein family UPF0492 DUF2513 PF10711.9 CAM39500.1 - 0.11 12.8 0.0 0.45 10.8 0.0 1.9 1 1 1 2 2 2 0 Hypothetical protein (DUF2513) TackOD1 PF18551.1 CAM39502.1 - 0.0025 17.5 6.1 0.13 12.0 1.0 2.1 1 1 1 2 2 2 2 Thaumarchaeal output domain 1 Stc1 PF12898.7 CAM39502.1 - 0.082 13.5 8.4 0.26 11.9 0.2 2.9 1 1 2 3 3 3 0 Stc1 domain RNHCP PF12647.7 CAM39502.1 - 0.11 12.4 3.4 0.22 11.5 1.6 2.1 2 1 0 2 2 2 0 RNHCP domain ArfGap PF01412.18 CAM39502.1 - 0.5 10.5 5.1 1.8 8.6 3.8 2.0 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf CDP-OH_P_transf PF01066.21 CAM39503.1 - 8.4e-13 48.9 1.7 8.4e-13 48.9 1.7 2.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase IBV_3A PF03617.13 CAM39503.1 - 0.1 12.6 1.0 0.26 11.3 1.0 1.6 1 0 0 1 1 1 0 IBV 3A protein Atg14 PF10186.9 CAM39504.1 - 0.0042 16.2 12.9 0.0042 16.2 12.9 9.4 4 3 3 9 9 9 3 Vacuolar sorting 38 and autophagy-related subunit 14 PRKG1_interact PF15898.5 CAM39504.1 - 0.011 16.6 12.4 0.011 16.6 12.4 13.9 7 3 4 13 13 13 0 cGMP-dependent protein kinase interacting domain APG6_N PF17675.1 CAM39504.1 - 0.085 13.4 0.1 0.085 13.4 0.1 15.6 8 5 4 12 12 12 0 Apg6 coiled-coil region HU-CCDC81_bac_2 PF18175.1 CAM39504.1 - 0.12 12.2 0.1 2.3 8.1 0.1 3.4 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 JIP_LZII PF16471.5 CAM39504.1 - 0.13 12.5 0.1 0.13 12.5 0.1 15.7 15 2 0 17 17 17 0 JNK-interacting protein leucine zipper II CHCH PF06747.13 CAM39506.1 - 8.1e-06 25.8 11.0 0.0014 18.7 5.6 2.4 2 0 0 2 2 2 2 CHCH domain MTCP1 PF08991.10 CAM39506.1 - 0.00041 20.5 4.9 0.01 16.1 0.9 2.3 2 0 0 2 2 2 2 Mature-T-Cell Proliferation I type CX9C PF16860.5 CAM39506.1 - 0.0035 17.3 3.5 0.0035 17.3 3.5 2.3 3 0 0 3 3 3 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Ecm29 PF13001.7 CAM39506.1 - 0.087 11.5 0.0 0.093 11.4 0.0 1.0 1 0 0 1 1 1 0 Proteasome stabiliser Cmc1 PF08583.10 CAM39506.1 - 2 8.5 13.6 18 5.4 5.8 3.4 2 2 1 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 CAM39506.1 - 5 6.9 10.5 1.2 8.9 1.7 2.7 2 1 1 3 3 3 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) COX6B PF02297.17 CAM39506.1 - 6.1 7.1 11.0 1.9 8.8 7.0 2.2 2 1 0 2 2 2 0 Cytochrome oxidase c subunit VIb Pkinase PF00069.25 CAM39507.1 - 5.2e-47 160.4 0.0 6.4e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM39507.1 - 3.4e-28 98.6 0.0 4.8e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FYVE PF01363.21 CAM39507.1 - 1e-08 35.1 12.5 2.3e-08 34.0 12.5 1.6 1 0 0 1 1 1 1 FYVE zinc finger Pkinase_fungal PF17667.1 CAM39507.1 - 0.00082 18.3 0.0 0.0013 17.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CAM39507.1 - 0.0022 17.9 0.0 0.0067 16.4 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 CAM39507.1 - 0.028 14.0 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family DnaJ PF00226.31 CAM39508.1 - 1.1e-06 28.7 0.0 2.6e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain RNF220 PF15926.5 CAM39508.1 - 0.087 12.4 0.2 0.087 12.4 0.2 3.0 3 1 0 3 3 3 0 E3 ubiquitin-protein ligase RNF220 zf-LITAF-like PF10601.9 CAM39508.1 - 8.7 6.7 15.2 25 5.2 9.1 2.7 2 1 0 2 2 2 0 LITAF-like zinc ribbon domain Metallophos PF00149.28 CAM39509.1 - 1.3e-33 117.2 0.0 2.1e-33 116.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SET PF00856.28 CAM39511.1 - 2.9e-13 50.6 0.0 2.9e-11 44.1 0.0 2.4 1 1 0 1 1 1 1 SET domain Dala_Dala_lig_C PF07478.13 CAM39511.1 - 4.1e-12 46.1 0.0 6.7e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CAM39511.1 - 0.00028 20.5 0.0 0.00043 19.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 CAM39511.1 - 0.028 14.5 0.0 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_4 PF13535.6 CAM39511.1 - 0.043 13.4 0.0 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain GARS_A PF01071.19 CAM39511.1 - 0.07 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Pkinase PF00069.25 CAM39512.1 - 2.3e-44 151.7 0.0 3.8e-44 151.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM39512.1 - 2.7e-33 115.4 0.0 3.3e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAM39512.1 - 0.0015 17.4 0.0 0.0022 16.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase TrmO_C PF18389.1 CAM39512.1 - 0.029 14.5 0.0 0.063 13.4 0.0 1.5 1 0 0 1 1 1 0 TrmO C-terminal domain SMP PF04927.12 CAM39513.1 - 0.015 15.8 0.2 0.029 14.8 0.2 1.6 1 0 0 1 1 1 0 Seed maturation protein PqiA PF04403.13 CAM39514.1 - 2.5e-12 46.9 23.3 8.1e-11 42.0 9.9 3.2 2 1 1 3 3 3 2 Paraquat-inducible protein A LapA_dom PF06305.11 CAM39514.1 - 0.043 13.6 0.0 0.043 13.6 0.0 3.5 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain Dynamitin PF04912.14 CAM39515.1 - 0.38 10.0 3.2 0.11 11.8 0.2 1.5 2 0 0 2 2 2 0 Dynamitin FAD_binding_3 PF01494.19 CAM39516.1 - 1.4e-08 34.4 0.1 1.3e-06 28.0 0.0 3.0 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 CAM39516.1 - 7.6e-07 29.3 0.0 2.3e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CAM39516.1 - 0.00029 20.0 0.1 0.00079 18.6 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 CAM39516.1 - 0.00058 20.4 0.0 0.0013 19.3 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CAM39516.1 - 0.00074 18.8 0.0 0.0031 16.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CAM39516.1 - 0.0013 18.4 0.2 0.004 16.8 0.0 1.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CAM39516.1 - 0.0041 16.2 0.1 0.037 13.1 0.0 2.4 3 0 0 3 3 3 1 Lycopene cyclase protein Thi4 PF01946.17 CAM39516.1 - 0.069 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 CAM39516.1 - 0.098 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-CSL PF05207.13 CAM39518.1 - 5.7e-15 54.8 0.1 8.4e-15 54.3 0.1 1.2 1 0 0 1 1 1 1 CSL zinc finger CLZ PF16526.5 CAM39519.1 - 0.034 14.5 0.7 0.094 13.1 0.7 1.8 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fzo_mitofusin PF04799.13 CAM39519.1 - 0.14 11.7 0.2 1.5 8.3 0.3 2.2 2 1 0 2 2 2 0 fzo-like conserved region Uso1_p115_C PF04871.13 CAM39519.1 - 2.4 8.5 7.1 0.51 10.7 3.0 1.9 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region HECT PF00632.25 CAM39520.1 - 4.2e-07 29.7 0.0 0.00014 21.5 0.0 2.7 3 0 0 3 3 3 2 HECT-domain (ubiquitin-transferase) RTT107_BRCT_5 PF16770.5 CAM39521.1 - 0.023 14.6 0.0 0.1 12.5 0.0 2.2 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain Spectrin_like PF18373.1 CAM39521.1 - 0.034 14.2 3.1 0.068 13.2 0.6 2.9 2 0 0 2 2 2 0 Spectrin like domain DUF3606 PF12244.8 CAM39521.1 - 0.39 10.7 3.8 0.22 11.5 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) DUF3584 PF12128.8 CAM39521.1 - 0.5 7.8 88.5 0.51 7.8 47.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Raco_middle PF17651.1 CAM39521.1 - 1.9 8.2 3.7 4.5 6.9 0.9 2.7 1 1 1 2 2 2 0 RACo middle region BLOC1_2 PF10046.9 CAM39521.1 - 6.6 7.1 45.4 0.18 12.2 6.0 6.9 2 1 5 8 8 8 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PKcGMP_CC PF16808.5 CAM39521.1 - 7.8 6.4 14.2 0.42 10.5 1.4 4.6 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ABC_membrane PF00664.23 CAM39522.1 - 7.5e-97 324.3 24.6 8.7e-53 179.7 9.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CAM39522.1 - 2.3e-69 232.2 0.0 9e-35 120.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CAM39522.1 - 1.2e-12 47.8 0.1 5.6e-06 25.9 0.0 3.6 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 CAM39522.1 - 4.5e-06 26.1 0.1 0.0044 16.3 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin AAA_29 PF13555.6 CAM39522.1 - 6.8e-06 25.7 0.2 0.062 13.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CAM39522.1 - 1.3e-05 25.2 0.0 0.11 12.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 CAM39522.1 - 2.2e-05 24.9 0.1 0.29 11.5 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 CAM39522.1 - 4.5e-05 23.7 1.2 0.18 12.1 0.1 3.7 2 2 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 CAM39522.1 - 6.1e-05 22.0 0.1 0.0016 17.4 0.1 2.4 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA PF00004.29 CAM39522.1 - 0.00012 22.5 0.9 1 9.8 0.1 4.0 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 CAM39522.1 - 0.00028 21.5 0.7 0.45 11.0 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 CAM39522.1 - 0.00038 20.3 0.0 0.29 10.8 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain Rad17 PF03215.15 CAM39522.1 - 0.00044 20.2 0.0 0.44 10.4 0.0 3.2 3 0 0 3 3 3 1 Rad17 P-loop domain ATP-synt_ab PF00006.25 CAM39522.1 - 0.00048 19.9 0.0 0.23 11.1 0.0 2.7 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.14 CAM39522.1 - 0.0006 19.8 0.0 0.5 10.4 0.0 3.7 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CAM39522.1 - 0.0015 18.9 0.0 3.8 8.0 0.0 3.1 2 0 0 2 2 2 1 RNA helicase G-alpha PF00503.20 CAM39522.1 - 0.0027 16.9 0.0 0.35 10.0 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit DUF87 PF01935.17 CAM39522.1 - 0.0044 17.1 0.4 2.1 8.4 0.1 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_7 PF12775.7 CAM39522.1 - 0.005 16.4 0.1 1.7 8.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_14 PF13173.6 CAM39522.1 - 0.0078 16.2 0.0 2.4 8.2 0.0 3.1 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 CAM39522.1 - 0.009 15.8 0.2 7.2 6.3 0.0 3.1 4 0 0 4 4 2 0 Viral (Superfamily 1) RNA helicase SbcCD_C PF13558.6 CAM39522.1 - 0.016 15.5 6.0 8.9 6.6 0.5 4.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 CAM39522.1 - 0.024 14.9 0.0 2.3 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CAM39522.1 - 0.03 13.9 1.0 8.6 5.9 0.0 3.3 4 0 0 4 4 4 0 AAA domain MoaE PF02391.17 CAM39522.1 - 0.034 14.4 0.6 4.7 7.5 0.0 3.6 4 0 0 4 4 3 0 MoaE protein MeaB PF03308.16 CAM39522.1 - 0.039 12.9 0.0 2.7 6.9 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 CAM39522.1 - 0.039 14.0 0.8 9.2 6.4 0.0 3.4 3 0 0 3 3 3 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 CAM39522.1 - 0.045 13.7 0.4 30 4.5 0.0 3.3 3 0 0 3 3 3 0 NTPase AAA_18 PF13238.6 CAM39522.1 - 0.064 13.8 0.0 13 6.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 CAM39522.1 - 0.066 12.4 0.0 11 5.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_21 PF13304.6 CAM39522.1 - 0.071 12.9 0.1 4.5 7.0 0.0 2.8 3 0 0 3 3 2 0 AAA domain, putative AbiEii toxin, Type IV TA system NB-ARC PF00931.22 CAM39522.1 - 0.075 12.2 0.1 5.4 6.1 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain DEAD PF00270.29 CAM39522.1 - 1.2 8.8 3.1 7 6.4 0.3 3.2 2 2 0 2 2 2 0 DEAD/DEAH box helicase CPBP PF02517.16 CAM39524.1 - 5.5e-20 71.5 0.2 5.5e-20 71.5 0.2 2.2 3 1 0 3 3 3 1 CPBP intramembrane metalloprotease Glucosamine_iso PF01182.20 CAM39525.1 - 2.6e-53 181.2 0.1 2.9e-53 181.0 0.1 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase AA_kinase PF00696.28 CAM39526.1 - 9.8e-42 143.2 0.2 1.2e-41 142.9 0.2 1.0 1 0 0 1 1 1 1 Amino acid kinase family Glucosamine_iso PF01182.20 CAM39528.1 - 2.6e-53 181.2 0.1 2.9e-53 181.0 0.1 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase AA_kinase PF00696.28 CAM39529.1 - 9.8e-42 143.2 0.2 1.2e-41 142.9 0.2 1.0 1 0 0 1 1 1 1 Amino acid kinase family ubiquitin PF00240.23 CAM39530.1 - 0 1453.9 71.4 1.1e-31 108.4 0.2 14.0 14 0 0 14 14 14 14 Ubiquitin family Rad60-SLD PF11976.8 CAM39530.1 - 3e-221 715.8 74.0 3.2e-15 55.7 0.2 14.0 14 0 0 14 14 14 14 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CAM39530.1 - 3e-68 226.3 39.9 0.0031 17.9 0.1 16.8 14 0 0 14 14 14 14 Ubiquitin-like domain TBK1_ULD PF18396.1 CAM39530.1 - 2.6e-48 161.8 30.5 0.11 12.5 0.0 14.2 14 0 0 14 14 14 14 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CAM39530.1 - 1.7e-43 147.0 47.5 0.13 12.6 0.1 14.1 14 0 0 14 14 14 14 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CAM39530.1 - 4.5e-35 120.1 30.1 1.1 9.4 0.0 15.2 14 0 0 14 14 14 14 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CAM39530.1 - 1.4e-30 105.9 14.4 6.6 7.4 0.0 14.1 1 1 5 14 14 14 12 DUF2407 ubiquitin-like domain DUF2870 PF11069.8 CAM39530.1 - 3.7e-20 72.1 0.1 92 3.5 0.0 14.5 14 0 0 14 14 14 0 Protein of unknown function (DUF2870) UDP-g_GGTase PF06427.11 CAM39530.1 - 4.8e-17 62.0 31.9 15 5.7 0.0 13.5 14 0 0 14 14 14 0 UDP-glucose:Glycoprotein Glucosyltransferase Big_7 PF17957.1 CAM39530.1 - 6.7e-16 58.8 0.1 58 4.6 0.0 12.1 14 0 0 14 14 14 0 Bacterial Ig domain ORF11CD3 PF10549.9 CAM39530.1 - 8.2e-11 41.9 0.1 3.9e+02 1.3 0.0 13.1 14 0 0 14 14 14 0 ORF11CD3 domain DUF969 PF06149.12 CAM39530.1 - 9.8e-11 41.5 15.9 74 2.7 0.0 13.2 14 0 0 14 14 14 0 Protein of unknown function (DUF969) DUF3861 PF12977.7 CAM39530.1 - 2.7e-09 37.1 23.1 97 3.2 0.0 13.5 14 0 0 14 14 14 0 Domain of Unknown Function with PDB structure (DUF3861) Ubiquitin_4 PF18036.1 CAM39530.1 - 0.011 15.7 99.6 75 3.5 0.2 26.1 28 0 0 28 28 28 0 Ubiquitin-like domain ProRS-C_2 PF09181.10 CAM39530.1 - 2.6 8.2 33.2 3.5e+02 1.4 0.1 12.5 14 0 0 14 14 14 0 Prolyl-tRNA synthetase, C-terminal Phage_integrase PF00589.22 CAM39531.1 - 7.9e-06 25.8 0.0 5.8e-05 22.9 0.0 2.6 2 0 0 2 2 2 1 Phage integrase family RVT_1 PF00078.27 CAM39531.1 - 0.0029 17.1 0.0 0.0078 15.7 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A17 PF05380.13 CAM39531.1 - 0.0049 16.9 0.1 0.055 13.5 0.0 2.4 1 1 1 2 2 2 1 Pao retrotransposon peptidase AAA PF00004.29 CAM39534.1 - 7.4e-10 39.4 0.0 5.5e-09 36.5 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CAM39534.1 - 4.6e-08 33.4 0.1 2.9e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CAM39534.1 - 5.8e-06 26.8 0.0 4.8e-05 23.8 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 CAM39534.1 - 0.0037 17.6 0.1 0.016 15.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 CAM39534.1 - 0.0064 15.6 0.0 0.022 13.8 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein NACHT PF05729.12 CAM39534.1 - 0.0067 16.4 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 CAM39534.1 - 0.0082 16.1 0.0 0.12 12.3 0.0 2.1 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_11 PF13086.6 CAM39534.1 - 0.019 14.7 0.0 0.045 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 CAM39534.1 - 0.022 14.0 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 CAM39534.1 - 0.042 13.6 0.1 0.24 11.1 0.0 2.2 1 1 1 2 2 2 0 AAA domain NB-ARC PF00931.22 CAM39534.1 - 0.058 12.6 0.0 0.098 11.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_7 PF12775.7 CAM39534.1 - 0.11 12.0 0.0 1.6 8.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region ResIII PF04851.15 CAM39534.1 - 0.18 11.8 0.0 0.37 10.8 0.0 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit PPR PF01535.20 CAM39535.1 - 2.3e-07 30.6 0.1 3.1 8.2 0.0 6.0 6 0 0 6 6 6 2 PPR repeat PPR_2 PF13041.6 CAM39535.1 - 0.016 15.4 0.9 2.9 8.2 0.0 4.7 6 0 0 6 6 6 0 PPR repeat family DUF2000 PF09391.10 CAM39535.1 - 0.042 13.8 1.4 0.18 11.7 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2000) NYD-SP28 PF14772.6 CAM39536.1 - 1.3e-15 57.2 4.4 1.3e-15 57.2 4.4 4.7 2 1 2 5 5 5 1 Sperm tail NYD-SP28_assoc PF14775.6 CAM39536.1 - 8.7e-05 22.5 0.9 0.00059 19.9 0.3 2.8 2 0 0 2 2 2 1 Sperm tail C-terminal domain DUF5521 PF17659.1 CAM39536.1 - 0.003 15.5 0.0 0.0057 14.6 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5521) SOAR PF16533.5 CAM39536.1 - 0.004 17.1 2.0 0.004 17.1 2.0 3.7 1 1 2 3 3 3 2 STIM1 Orai1-activating region CVNH PF08881.10 CAM39536.1 - 0.85 10.3 2.9 5.2 7.8 1.7 2.8 2 1 0 2 2 2 0 CVNH domain FIST PF08495.10 CAM39537.1 - 0.00063 19.8 0.1 0.0013 18.8 0.1 1.6 1 0 0 1 1 1 1 FIST N domain DUF2550 PF10739.9 CAM39538.1 - 0.014 15.4 1.4 0.038 14.0 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2550) Ank_2 PF12796.7 CAM39539.2 - 2.2e-08 34.6 0.1 1.4e-06 28.7 0.0 2.8 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CAM39539.2 - 0.00011 22.4 0.4 0.18 12.5 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 CAM39539.2 - 0.00041 20.8 0.1 0.003 18.1 0.0 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) IQ PF00612.27 CAM39539.2 - 0.0013 18.3 9.5 0.33 10.9 0.0 4.8 4 0 0 4 4 4 2 IQ calmodulin-binding motif Ank PF00023.30 CAM39539.2 - 0.013 16.0 7.1 0.058 13.9 0.1 4.5 4 1 0 4 4 4 0 Ankyrin repeat Ank_5 PF13857.6 CAM39539.2 - 0.041 14.2 0.0 0.61 10.5 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Proteasome PF00227.26 CAM39542.1 - 3.3e-38 131.1 0.0 3.8e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TFIIS_C PF01096.18 CAM39543.1 - 0.00067 19.5 3.1 0.00067 19.5 3.1 3.1 3 1 0 3 3 3 1 Transcription factor S-II (TFIIS) zf-Sec23_Sec24 PF04810.15 CAM39543.1 - 0.0021 18.0 2.7 0.0021 18.0 2.7 1.9 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger RNA_POL_M_15KD PF02150.16 CAM39543.1 - 0.0038 17.1 5.9 0.0038 17.1 5.9 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Ogr_Delta PF04606.12 CAM39543.1 - 0.015 15.3 2.3 0.015 15.3 2.3 2.4 2 2 0 2 2 2 0 Ogr/Delta-like zinc finger zf-ribbon_3 PF13248.6 CAM39543.1 - 0.27 10.7 10.7 3.3 7.3 1.1 3.7 4 0 0 4 4 4 0 zinc-ribbon domain HNH_5 PF14279.6 CAM39543.1 - 0.33 10.8 0.1 0.33 10.8 0.1 2.7 3 0 0 3 3 3 0 HNH endonuclease zinc_ribbon_2 PF13240.6 CAM39543.1 - 1.4 8.7 11.7 0.3 10.9 0.6 3.3 3 0 0 3 3 3 0 zinc-ribbon domain Nudix_N_2 PF14803.6 CAM39543.1 - 1.8 8.5 10.6 4.6 7.2 1.4 2.9 2 1 0 2 2 2 0 Nudix N-terminal Zn_Tnp_IS1595 PF12760.7 CAM39543.1 - 2.2 8.4 14.0 0.26 11.3 1.6 2.7 2 2 0 2 2 2 0 Transposase zinc-ribbon domain Zn_ribbon_recom PF13408.6 CAM39543.1 - 4.7 7.8 8.5 0.77 10.3 2.2 2.3 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain Lar_restr_allev PF14354.6 CAM39543.1 - 8 6.9 13.8 0.093 13.1 2.3 2.7 2 1 0 2 2 2 0 Restriction alleviation protein Lar Fumble PF03630.14 CAM39545.1 - 9.8e-93 310.9 0.0 2.1e-92 309.9 0.0 1.5 1 0 0 1 1 1 1 Fumble AMP-binding PF00501.28 CAM39545.1 - 3e-13 49.1 0.3 2.3e-08 33.1 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Exo_endo_phos PF03372.23 CAM39545.1 - 9.7e-08 31.8 0.0 1.8e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Spo7_2_N PF15407.6 CAM39547.1 - 0.02 14.5 0.0 0.056 13.1 0.0 1.8 2 0 0 2 2 2 0 Sporulation protein family 7 RRM_1 PF00076.22 CAM39547.1 - 0.048 13.5 0.0 0.37 10.7 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CAM39547.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif DSPc PF00782.20 CAM39548.1 - 4.5e-24 84.8 0.0 7.8e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain LRR_8 PF13855.6 CAM39548.1 - 7e-09 35.3 8.5 2.3e-05 24.0 2.5 3.7 3 0 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 CAM39548.1 - 6.6e-06 26.4 11.7 0.00024 21.4 5.2 3.9 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) Y_phosphatase PF00102.27 CAM39548.1 - 0.0048 16.5 0.0 0.0077 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase LRR_9 PF14580.6 CAM39548.1 - 0.012 15.1 2.2 3.1 7.3 0.0 2.4 2 0 0 2 2 2 0 Leucine-rich repeat Init_tRNA_PT PF04179.12 CAM39548.1 - 0.089 13.1 0.1 0.27 11.6 0.0 1.8 2 0 0 2 2 2 0 Rit1 DUSP-like domain CDKN3 PF05706.12 CAM39548.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Histone PF00125.24 CAM39552.1 - 4.7e-12 46.4 0.1 6.1e-12 46.0 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CAM39552.1 - 0.0097 16.2 0.3 0.023 15.0 0.3 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Cylicin_N PF15241.6 CAM39552.1 - 0.051 13.7 0.3 0.073 13.2 0.3 1.3 1 0 0 1 1 1 0 Cylicin N-terminus DHHC PF01529.20 CAM39553.1 - 2.4e-32 111.8 3.8 2.4e-32 111.8 3.8 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase LapA_dom PF06305.11 CAM39553.1 - 0.041 13.7 0.2 0.12 12.2 0.2 1.8 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain AzlD PF05437.12 CAM39553.1 - 0.77 10.0 5.9 6 7.1 0.1 3.2 2 1 1 3 3 3 0 Branched-chain amino acid transport protein (AzlD) DAO PF01266.24 CAM39555.1 - 2.8e-42 145.6 0.2 5.2e-42 144.7 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO_C PF16901.5 CAM39555.1 - 9.3e-34 116.0 0.4 1.8e-33 115.1 0.4 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 CAM39555.1 - 0.0097 15.0 1.3 0.019 14.1 1.3 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 CAM39555.1 - 0.019 14.3 1.8 0.033 13.5 1.8 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CAM39555.1 - 0.034 13.4 0.1 0.15 11.3 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 CAM39555.1 - 0.056 12.7 0.0 0.2 11.0 0.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 CAM39555.1 - 0.068 13.1 0.2 0.19 11.6 0.2 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 CAM39555.1 - 0.12 11.5 1.1 1.1 8.2 0.2 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A NADH-u_ox-rdase PF10785.9 CAM39556.1 - 2.6e-12 47.3 0.3 4.7e-12 46.4 0.3 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit PAPS_reduct PF01507.19 CAM39558.1 - 2.1e-22 80.0 0.0 7.6e-17 61.9 0.0 2.1 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.20 CAM39558.1 - 0.068 12.9 0.0 0.087 12.6 0.0 1.2 1 0 0 1 1 1 0 PP-loop family zf_CCCH_4 PF18345.1 CAM39561.1 - 2.4e-07 30.6 10.1 0.00018 21.4 3.4 2.8 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 CAM39561.1 - 6.9e-06 25.8 8.5 3.6e-05 23.5 0.6 2.9 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-HIT PF04438.16 CAM39561.1 - 7.3e-06 25.7 13.6 2.3e-05 24.2 13.6 1.9 1 0 0 1 1 1 1 HIT zinc finger Torus PF16131.5 CAM39561.1 - 0.00064 20.4 4.7 0.087 13.5 0.2 2.7 1 1 1 2 2 2 2 Torus domain zf-CCCH_4 PF18044.1 CAM39561.1 - 0.0085 15.9 1.6 0.0085 15.9 1.6 3.2 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CAM39561.1 - 0.14 12.7 7.1 0.21 12.1 1.3 2.8 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger RNB PF00773.19 CAM39564.1 - 3.4e-94 315.8 0.0 5.5e-94 315.1 0.0 1.3 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 CAM39564.1 - 1.8e-20 72.7 0.0 3.6e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 CAM39564.1 - 3.2e-09 36.7 0.0 8.4e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 Rrp44-like cold shock domain CSD2 PF17876.1 CAM39564.1 - 2.7e-06 27.5 0.0 5.1e-05 23.4 0.0 2.6 2 0 0 2 2 2 1 Cold shock domain Rrp44_S1 PF17215.3 CAM39564.1 - 0.0009 19.2 0.1 0.0037 17.2 0.0 2.0 1 1 1 2 2 2 1 S1 domain Dis3l2_C_term PF17877.1 CAM39564.1 - 0.014 15.8 0.0 0.04 14.2 0.0 1.7 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal DUF3695 PF12494.8 CAM39564.1 - 0.07 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3695) SMBP PF16785.5 CAM39564.1 - 7.3 6.9 7.9 0.22 11.8 0.5 2.2 3 0 0 3 3 3 0 Small metal-binding protein MtN3_slv PF03083.16 CAM39566.1 - 8e-21 73.9 9.8 3.9e-12 46.0 1.6 2.4 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Tox-ODYAM1 PF15642.6 CAM39566.1 - 0.026 13.5 0.1 0.036 13.1 0.1 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus ThiF PF00899.21 CAM39567.1 - 1.2e-08 34.6 0.1 1.9e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 CAM39569.2 - 2.1e-22 79.8 0.2 4.2e-22 78.8 0.2 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 CAM39569.2 - 6.3e-06 26.2 0.0 0.00067 19.6 0.0 2.3 1 1 1 2 2 2 2 NAD(P)H-binding 3Beta_HSD PF01073.19 CAM39569.2 - 0.0011 18.0 0.0 0.0018 17.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 CAM39569.2 - 0.0028 17.1 0.0 0.0048 16.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 CAM39569.2 - 0.0037 17.7 0.0 0.0074 16.7 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AAA PF00004.29 CAM39571.1 - 2.5e-40 138.0 0.0 5.4e-40 136.9 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAM39571.1 - 4.2e-10 39.3 0.3 1.6e-09 37.4 0.0 2.3 2 1 0 2 2 2 1 AAA+ lid domain Vps4_C PF09336.10 CAM39571.1 - 1.6e-08 34.4 0.4 5.1e-08 32.8 0.3 1.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.14 CAM39571.1 - 1.6e-06 28.1 0.1 0.00064 19.7 0.0 3.5 4 1 0 4 4 4 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CAM39571.1 - 8.5e-06 25.6 0.0 2.1e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CAM39571.1 - 0.00016 22.1 0.0 0.0006 20.2 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CAM39571.1 - 0.00028 21.2 0.1 0.0092 16.3 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_25 PF13481.6 CAM39571.1 - 0.00077 19.1 0.2 0.064 12.8 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 CAM39571.1 - 0.0014 18.4 0.0 0.0032 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CAM39571.1 - 0.0019 18.8 0.4 0.006 17.1 0.0 2.1 3 0 0 3 3 1 1 AAA domain AAA_14 PF13173.6 CAM39571.1 - 0.0022 18.0 0.0 0.006 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CAM39571.1 - 0.0023 17.4 0.0 0.0049 16.3 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 CAM39571.1 - 0.0027 17.6 0.1 0.074 13.0 0.0 2.6 3 0 0 3 3 3 1 NACHT domain ATPase PF06745.13 CAM39571.1 - 0.0034 16.8 0.1 1.1 8.5 0.0 2.7 2 1 1 3 3 3 1 KaiC AAA_2 PF07724.14 CAM39571.1 - 0.0075 16.4 0.0 0.03 14.5 0.0 2.1 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 CAM39571.1 - 0.0076 15.5 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 CAM39571.1 - 0.0081 15.9 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 CAM39571.1 - 0.015 14.8 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 CAM39571.1 - 0.016 15.6 0.0 0.04 14.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 CAM39571.1 - 0.016 15.3 0.0 0.042 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 CAM39571.1 - 0.041 13.0 0.5 0.12 11.5 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 TsaE PF02367.17 CAM39571.1 - 0.053 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 CAM39571.1 - 0.082 12.1 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.6 CAM39571.1 - 0.095 12.9 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CAM39571.1 - 0.12 12.1 0.0 0.53 10.0 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.11 CAM39571.1 - 0.13 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 CAM39571.1 - 0.16 11.4 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DUF4635 PF15466.6 CAM39571.1 - 0.16 11.4 0.0 0.41 10.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) ABC_tran PF00005.27 CAM39571.1 - 0.17 12.4 0.0 0.32 11.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_17 PF13207.6 CAM39571.1 - 0.17 12.3 0.6 0.77 10.2 0.0 2.3 3 0 0 3 3 2 0 AAA domain Carn_acyltransf PF00755.20 CAM39575.1 - 0.00033 19.4 0.0 0.00049 18.9 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase RNB PF00773.19 CAM39576.1 - 8.2e-89 298.1 0.0 1.1e-88 297.8 0.0 1.1 1 0 0 1 1 1 1 RNB domain WD40 PF00400.32 CAM39578.1 - 0.049 14.5 0.4 47 5.1 0.1 4.5 3 1 0 3 3 3 0 WD domain, G-beta repeat WD40_3 PF15911.5 CAM39578.1 - 0.069 13.2 0.0 15 5.7 0.0 4.0 4 0 0 4 4 4 0 WD domain, G-beta repeat Carb_anhydrase PF00194.21 CAM39579.1 - 7.2e-29 101.1 0.0 1.1e-28 100.5 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Apt1 PF10351.9 CAM39579.1 - 1 8.1 8.7 1.8 7.4 8.7 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 CAM39579.1 - 1.2 7.8 6.4 2.1 7.0 6.4 1.2 1 0 0 1 1 1 0 Presenilin Mucin PF01456.17 CAM39579.1 - 1.6 8.7 18.5 0.34 10.9 11.9 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein Carboxyl_trans PF01039.22 CAM39581.1 - 3.1e-174 580.3 0.0 3.5e-174 580.1 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 CAM39581.1 - 0.0005 19.6 0.0 0.0013 18.2 0.0 1.7 2 0 0 2 2 2 1 Malonate decarboxylase gamma subunit (MdcE) ACCA PF03255.14 CAM39581.1 - 0.086 12.7 0.1 0.77 9.6 0.0 2.3 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit TPR_2 PF07719.17 CAM39582.1 - 1.7e-07 30.8 0.0 0.91 9.8 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CAM39582.1 - 9.4e-07 28.4 0.7 0.5 10.3 0.0 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 CAM39582.1 - 3.9e-05 24.2 4.7 0.014 16.1 0.6 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CAM39582.1 - 0.00055 20.2 1.6 0.24 11.7 0.3 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat zf-MYND PF01753.18 CAM39582.1 - 0.0089 16.1 8.2 0.022 14.8 8.2 1.8 1 0 0 1 1 1 1 MYND finger TPR_19 PF14559.6 CAM39582.1 - 0.031 14.8 0.5 4 8.0 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2560 PF10834.8 CAM39582.1 - 0.062 13.5 0.0 0.23 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2560) Pkinase PF00069.25 CAM39584.1 - 1.8e-62 211.1 0.0 2e-62 210.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM39584.1 - 2e-38 132.1 0.0 2.5e-38 131.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM39584.1 - 2.4e-06 27.1 0.0 3.4e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CAM39584.1 - 0.00027 20.0 0.1 0.00043 19.3 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CAM39584.1 - 0.0044 17.0 1.3 0.026 14.5 0.6 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CAM39584.1 - 0.0045 15.8 0.0 0.0063 15.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 CAM39584.1 - 0.0055 16.3 0.1 0.83 9.2 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 CAM39584.1 - 0.024 13.7 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 CAM39584.1 - 0.025 13.9 0.1 0.044 13.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 CAM39584.1 - 0.037 13.5 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL GP52 PF17468.2 CAM39584.1 - 0.12 12.6 0.0 0.43 10.8 0.0 1.9 1 0 0 1 1 1 0 Phage gene product 52 AAA_23 PF13476.6 CAM39585.1 - 1.9e-27 97.1 0.0 1.9e-27 97.1 0.0 6.6 2 2 2 4 4 2 1 AAA domain SMC_N PF02463.19 CAM39585.1 - 1.5e-14 54.0 0.0 5.2e-07 29.3 0.0 2.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 CAM39585.1 - 1.2e-10 41.7 3.8 0.00014 21.7 0.8 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 CAM39585.1 - 7.4e-08 32.5 0.1 0.0011 18.8 0.1 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 CAM39585.1 - 1.2e-07 31.9 0.0 4.1e-07 30.1 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 CAM39585.1 - 0.0019 17.9 0.0 0.004 16.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 CAM39585.1 - 0.0021 18.6 16.0 0.0034 17.9 0.0 5.0 4 2 0 4 4 3 2 ABC transporter Rad50_zn_hook PF04423.14 CAM39585.1 - 0.041 13.7 0.0 0.48 10.3 0.0 3.1 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-C2H2_6 PF13912.6 CAM39585.1 - 0.1 12.7 1.1 0.55 10.3 0.0 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger RsgA_GTPase PF03193.16 CAM39585.1 - 0.47 10.3 0.0 0.47 10.3 0.0 3.3 4 0 0 4 4 4 0 RsgA GTPase Octopine_DH PF02317.17 CAM39585.1 - 0.59 10.2 4.0 1.7 8.8 0.1 3.5 3 0 0 3 3 3 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Ribosomal_S26e PF01283.19 CAM39586.1 - 8.6e-36 122.7 3.6 9.1e-36 122.6 3.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Rad51 PF08423.11 CAM39587.1 - 1.3e-128 427.6 0.4 2.1e-128 427.0 0.2 1.4 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.6 CAM39587.1 - 1.3e-10 41.2 0.1 2e-10 40.6 0.1 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 CAM39587.1 - 3e-10 40.0 0.1 4.9e-10 39.3 0.1 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 CAM39587.1 - 4.1e-05 24.1 0.1 0.00012 22.6 0.1 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain ATPase PF06745.13 CAM39587.1 - 0.00019 20.9 0.6 0.00069 19.0 0.6 1.9 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 CAM39587.1 - 0.0038 16.6 0.1 0.016 14.5 0.0 1.9 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 CAM39587.1 - 0.042 14.1 0.1 0.1 12.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain PAXNEB PF05625.11 CAM39587.1 - 0.22 10.7 0.1 0.74 8.9 0.0 1.7 2 0 0 2 2 2 0 PAXNEB protein Nucleoside_tran PF01733.18 CAM39588.1 - 5e-32 111.5 8.0 5e-32 111.5 8.0 2.2 2 1 0 2 2 2 1 Nucleoside transporter Mod_r PF07200.13 CAM39589.1 - 3.6e-08 33.6 0.3 3.6e-08 33.6 0.3 1.5 2 0 0 2 2 1 1 Modifier of rudimentary (Mod(r)) protein Csm1_N PF18504.1 CAM39589.1 - 0.0034 17.7 2.8 0.0034 17.7 2.8 2.5 2 1 1 3 3 3 1 Csm1 N-terminal domain TMCO5 PF14992.6 CAM39589.1 - 0.035 13.7 1.6 0.049 13.2 1.6 1.2 1 0 0 1 1 1 0 TMCO5 family ADIP PF11559.8 CAM39589.1 - 0.037 14.1 3.0 0.15 12.2 3.0 2.0 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4201 PF13870.6 CAM39589.1 - 0.04 13.6 5.2 0.021 14.6 2.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) TSC22 PF01166.18 CAM39589.1 - 0.045 14.1 0.8 1.6 9.1 0.4 3.0 1 1 1 2 2 2 0 TSC-22/dip/bun family CENP-H PF05837.12 CAM39589.1 - 0.054 13.9 1.6 0.13 12.7 1.6 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) JIP_LZII PF16471.5 CAM39589.1 - 0.064 13.4 2.0 0.16 12.2 2.0 1.7 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II APG6_N PF17675.1 CAM39589.1 - 0.074 13.6 1.2 0.29 11.6 0.2 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region Lectin_N PF03954.14 CAM39589.1 - 0.11 12.3 1.9 0.16 11.7 0.3 2.0 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Fib_alpha PF08702.10 CAM39589.1 - 0.13 12.4 5.7 0.31 11.2 0.7 3.0 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family bZIP_2 PF07716.15 CAM39589.1 - 0.16 12.1 4.2 0.14 12.3 1.2 2.4 1 1 1 2 2 2 0 Basic region leucine zipper Syntaxin_2 PF14523.6 CAM39589.1 - 0.17 12.3 2.5 1.6 9.2 2.6 2.6 1 1 0 1 1 1 0 Syntaxin-like protein GAS PF13851.6 CAM39589.1 - 0.19 11.0 6.6 0.37 10.1 2.5 2.2 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding ZapB PF06005.12 CAM39589.1 - 0.2 12.1 5.5 0.076 13.5 2.6 1.8 2 0 0 2 2 1 0 Cell division protein ZapB Seryl_tRNA_N PF02403.22 CAM39589.1 - 0.25 11.6 2.9 0.26 11.5 0.7 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Cnn_1N PF07989.11 CAM39589.1 - 0.29 11.3 5.2 0.11 12.6 1.4 2.2 2 1 1 3 3 2 0 Centrosomin N-terminal motif 1 FlaC_arch PF05377.11 CAM39589.1 - 0.46 10.9 6.1 0.75 10.2 2.4 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Fungal_TACC PF12709.7 CAM39589.1 - 0.47 10.9 3.3 0.28 11.6 0.9 1.9 2 0 0 2 2 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF948 PF06103.11 CAM39589.1 - 0.6 10.4 3.9 0.55 10.5 1.6 2.2 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF948) DivIC PF04977.15 CAM39589.1 - 2 8.3 6.4 0.57 10.0 2.1 2.3 2 1 1 3 3 3 0 Septum formation initiator DUF1664 PF07889.12 CAM39589.1 - 2.7 8.0 5.6 0.93 9.5 1.7 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Pkinase PF00069.25 CAM39590.1 - 1.7e-54 185.0 0.0 6.1e-37 127.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM39590.1 - 7.3e-22 77.9 0.0 7.2e-20 71.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 CAM39590.1 - 0.014 14.7 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CAM39590.1 - 0.015 15.3 0.1 0.068 13.1 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CAM39590.1 - 0.098 11.6 0.0 0.43 9.5 0.0 1.8 1 1 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 CAM39590.1 - 0.1 11.9 0.2 3.4 6.9 0.1 2.5 3 0 0 3 3 3 0 Kinase-like FTA2 PF13095.6 CAM39590.1 - 0.15 11.7 0.1 10 5.6 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SlyX PF04102.12 CAM39591.1 - 0.012 16.2 10.4 1.7 9.3 4.5 3.3 3 0 0 3 3 3 0 SlyX Spc29 PF17082.5 CAM39591.1 - 0.053 13.4 1.4 0.097 12.5 0.8 1.7 1 1 0 1 1 1 0 Spindle Pole Component 29 Med9 PF07544.13 CAM39591.1 - 0.19 11.8 1.3 22 5.2 0.8 2.6 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF5082 PF16888.5 CAM39591.1 - 0.25 11.6 4.0 7 7.0 1.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) ATG16 PF08614.11 CAM39591.1 - 0.5 10.6 6.4 0.11 12.7 2.5 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) SSFA2_C PF14723.6 CAM39591.1 - 5 7.0 9.4 0.3 11.0 1.3 2.9 2 1 1 3 3 3 0 Sperm-specific antigen 2 C-terminus ZapB PF06005.12 CAM39591.1 - 8.9 6.8 9.1 37 4.9 0.0 3.2 3 0 0 3 3 3 0 Cell division protein ZapB DMAP1 PF05499.12 CAM39592.1 - 1.1 9.2 6.9 1.1 9.1 6.9 1.0 1 0 0 1 1 1 0 DNA methyltransferase 1-associated protein 1 (DMAP1) DUF2462 PF09495.10 CAM39592.1 - 1.3 9.8 14.4 0.16 12.7 9.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2462) AAA_6 PF12774.7 CAM39593.2 - 3.3e-150 499.6 0.0 3.3e-149 496.3 0.0 2.5 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CAM39593.2 - 2.8e-118 395.5 4.0 2.8e-118 395.5 4.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 CAM39593.2 - 9.7e-103 343.6 0.0 4.1e-102 341.5 0.0 2.1 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 CAM39593.2 - 1.8e-89 299.5 0.0 3.1e-87 292.2 0.0 3.6 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CAM39593.2 - 2.8e-81 271.8 2.8 2.8e-81 271.8 2.8 2.4 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 CAM39593.2 - 7e-65 217.9 0.0 1.9e-59 200.2 0.0 4.0 4 0 0 4 4 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CAM39593.2 - 2.6e-53 180.2 0.0 6.9e-53 178.8 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 CAM39593.2 - 6.5e-46 156.9 2.8 2e-45 155.4 2.7 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 CAM39593.2 - 1.1e-45 154.6 1.3 5e-44 149.2 0.1 3.5 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 CAM39593.2 - 4.1e-16 59.0 0.1 1.4e-15 57.3 0.1 1.9 1 0 0 1 1 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 CAM39593.2 - 3.3e-15 56.3 0.0 3.3e-14 53.1 0.0 2.9 4 0 0 4 4 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CAM39593.2 - 4.7e-13 49.3 0.1 0.00016 21.6 0.0 5.9 4 2 0 4 4 4 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CAM39593.2 - 1.7e-06 28.4 0.1 0.0063 16.9 0.0 3.6 4 0 0 4 4 3 1 RNA helicase AAA_22 PF13401.6 CAM39593.2 - 9.6e-06 25.9 3.8 1.7 8.9 0.0 4.8 4 0 0 4 4 4 2 AAA domain AAA_30 PF13604.6 CAM39593.2 - 1.7e-05 24.6 3.5 0.74 9.5 0.0 3.7 3 0 0 3 3 3 3 AAA domain AAA_16 PF13191.6 CAM39593.2 - 2.9e-05 24.5 0.6 0.69 10.3 0.0 4.9 4 0 0 4 4 4 2 AAA ATPase domain AAA_18 PF13238.6 CAM39593.2 - 4.5e-05 24.0 0.2 0.23 12.0 0.0 4.0 4 0 0 4 4 3 1 AAA domain AAA PF00004.29 CAM39593.2 - 6.8e-05 23.3 0.1 1.6 9.2 0.0 4.3 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 CAM39593.2 - 0.0085 15.2 4.8 0.3 10.1 0.1 4.4 6 0 0 6 6 6 1 Type II/IV secretion system protein AAA_24 PF13479.6 CAM39593.2 - 0.039 13.7 0.6 5.7 6.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain PhoH PF02562.16 CAM39593.2 - 0.05 13.1 3.7 2.5 7.5 0.0 3.3 3 0 0 3 3 3 0 PhoH-like protein IstB_IS21 PF01695.17 CAM39593.2 - 0.087 12.6 1.0 25 4.5 0.0 3.5 3 0 0 3 3 3 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 CAM39593.2 - 0.094 12.1 3.5 0.71 9.2 0.0 3.6 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI Baculo_PEP_C PF04513.12 CAM39593.2 - 0.097 12.7 6.6 6.6 6.8 0.1 5.1 5 0 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_29 PF13555.6 CAM39593.2 - 0.22 11.3 0.9 4.2 7.2 0.0 3.1 4 0 0 4 4 2 0 P-loop containing region of AAA domain SRP54 PF00448.22 CAM39593.2 - 0.68 9.5 3.1 12 5.5 0.0 3.0 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 CAM39593.2 - 1.2 9.3 4.7 35 4.5 0.0 4.0 3 0 0 3 3 3 0 AAA domain Pkinase PF00069.25 CAM39594.1 - 1.5e-51 175.3 0.0 2.5e-51 174.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM39594.1 - 4.7e-36 124.4 0.0 8.6e-36 123.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Chloroa_b-bind PF00504.21 CAM39594.1 - 0.098 13.2 0.0 0.36 11.3 0.0 1.9 2 0 0 2 2 2 0 Chlorophyll A-B binding protein ER_lumen_recept PF00810.18 CAM39595.1 - 1.8e-48 165.1 8.7 1.8e-48 165.1 8.7 1.6 2 0 0 2 2 2 1 ER lumen protein retaining receptor ATP_synt_H PF05493.13 CAM39596.1 - 5.2e-19 68.5 5.5 5.7e-19 68.3 5.5 1.0 1 0 0 1 1 1 1 ATP synthase subunit H Phage_holin_3_6 PF07332.11 CAM39596.1 - 0.35 10.9 4.7 0.38 10.8 4.7 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III WD40 PF00400.32 CAM39597.1 - 4.8e-12 46.2 7.4 0.00075 20.3 0.1 6.7 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM39597.1 - 5.1e-11 42.7 0.0 0.0034 17.6 0.0 3.5 3 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CAM39597.1 - 0.5 9.3 2.2 1.1 8.1 0.7 2.4 2 2 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF5538 PF17692.1 CAM39599.1 - 0.12 12.5 0.0 0.41 10.7 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5538) Ank_4 PF13637.6 CAM39600.1 - 1.7e-18 66.7 0.1 7.3e-08 32.8 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CAM39600.1 - 1.3e-17 64.1 1.4 9.5e-12 45.4 0.2 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CAM39600.1 - 6e-14 51.9 1.6 1.7e-07 31.4 0.2 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CAM39600.1 - 8.5e-11 41.1 0.3 0.0008 19.7 0.1 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 CAM39600.1 - 7.7e-07 29.3 0.1 0.013 15.9 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat Metallophos PF00149.28 CAM39601.1 - 4.8e-37 128.4 0.1 6.4e-37 128.0 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CAM39601.1 - 6e-17 61.8 0.8 1.1e-16 60.9 0.8 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain BTB_2 PF02214.22 CAM39602.2 - 9.7e-12 45.1 0.0 1.4e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Phage_TAC_6 PF09550.10 CAM39602.2 - 0.75 10.3 2.9 2.8 8.4 0.3 2.3 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC DUF4539 PF15072.6 CAM39603.2 - 1.5e-13 50.6 0.0 2.1e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) SNARE_assoc PF09335.11 CAM39604.1 - 3.5e-09 37.2 1.5 3.5e-09 37.2 1.5 3.1 3 0 0 3 3 3 1 SNARE associated Golgi protein EF-hand_5 PF13202.6 CAM39604.1 - 0.00049 19.5 0.0 0.001 18.4 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CAM39604.1 - 0.00056 19.6 0.0 0.0023 17.7 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CAM39604.1 - 0.012 15.1 0.0 0.041 13.4 0.0 2.0 2 0 0 2 2 2 0 EF hand Sas10_Utp3 PF04000.15 CAM39605.2 - 1.2e-17 64.3 2.9 1.4e-17 64.1 1.1 2.1 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Sas10 PF09368.10 CAM39605.2 - 6.8e-16 58.5 5.8 1.9e-15 57.1 5.8 1.8 1 0 0 1 1 1 1 Sas10 C-terminal domain IclR PF01614.18 CAM39608.1 - 0.092 12.6 0.6 0.12 12.2 0.6 1.2 1 0 0 1 1 1 0 Bacterial transcriptional regulator SNF2_N PF00176.23 CAM39609.1 - 6.7e-52 176.3 0.0 6.3e-51 173.1 0.0 2.0 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CAM39609.1 - 6.4e-17 61.9 0.4 2.2e-16 60.2 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 CAM39609.1 - 7.4e-07 29.1 3.5 1.7e-06 28.0 3.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger ResIII PF04851.15 CAM39609.1 - 1.6e-06 28.2 0.3 7.1e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 CAM39609.1 - 6.8e-06 25.9 6.0 1.7e-05 24.6 6.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CAM39609.1 - 7.8e-06 25.7 5.4 1.7e-05 24.6 5.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CAM39609.1 - 1.3e-05 24.9 6.4 3e-05 23.8 6.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-4CXXC_R1 PF10497.9 CAM39609.1 - 0.0001 22.5 6.5 0.00025 21.2 6.5 1.6 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-RING_2 PF13639.6 CAM39609.1 - 0.00011 22.5 6.5 0.00011 22.5 6.5 2.0 2 0 0 2 2 2 1 Ring finger domain ERCC3_RAD25_C PF16203.5 CAM39609.1 - 0.00041 19.6 0.5 0.00078 18.7 0.5 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 CAM39609.1 - 0.0025 17.6 0.0 0.0054 16.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_2 PF13923.6 CAM39609.1 - 0.0034 17.2 10.9 0.019 14.8 10.9 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CAM39609.1 - 0.005 16.7 6.0 0.014 15.3 6.0 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CAM39609.1 - 0.012 15.7 5.7 0.026 14.7 5.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Sec20 PF03908.13 CAM39609.1 - 0.021 14.7 2.0 0.34 10.8 0.4 2.7 2 0 0 2 2 2 0 Sec20 zf-rbx1 PF12678.7 CAM39609.1 - 1.2 9.5 8.3 0.37 11.1 4.4 2.2 1 1 1 2 2 2 0 RING-H2 zinc finger domain PAP_assoc PF03828.19 CAM39612.1 - 6.3e-12 45.5 0.0 1.5e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase DSPc PF00782.20 CAM39613.1 - 1.4e-17 63.7 0.2 1.6e-16 60.3 0.2 2.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain EF-hand_7 PF13499.6 CAM39614.1 - 1.3e-14 54.4 1.5 3e-06 27.6 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CAM39614.1 - 9.1e-13 46.8 2.8 2.6e-06 26.6 0.0 3.9 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 CAM39614.1 - 1.5e-12 47.6 0.0 7.7e-11 42.2 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_6 PF13405.6 CAM39614.1 - 4.3e-12 44.9 2.3 3.7e-06 26.4 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 CAM39614.1 - 1.5e-07 31.2 2.7 0.00076 19.3 0.1 3.8 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 CAM39614.1 - 4.4e-05 22.8 1.1 0.037 13.5 0.0 3.4 3 0 0 3 3 3 2 EF hand EFhand_Ca_insen PF08726.10 CAM39614.1 - 0.065 13.3 0.2 0.2 11.8 0.1 1.9 1 1 1 2 2 2 0 Ca2+ insensitive EF hand RNA_pol_Rpb8 PF03870.15 CAM39615.1 - 1.1e-35 122.8 0.0 1.3e-35 122.6 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 CAM39615.1 - 0.0016 18.5 0.3 0.49 10.5 0.0 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G Myco_19_kDa PF05481.12 CAM39615.1 - 0.13 12.5 0.1 0.17 12.2 0.1 1.2 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen PP_kinase_C PF13090.6 CAM39616.1 - 0.18 11.2 0.0 0.37 10.2 0.0 1.4 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain 2 Patatin PF01734.22 CAM39616.1 - 2.1 8.5 7.5 2.5 8.2 1.2 2.3 1 1 1 2 2 2 0 Patatin-like phospholipase CSD PF00313.22 CAM39618.1 - 9e-16 57.5 0.3 1.2e-15 57.1 0.3 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain Stm1_N PF09598.10 CAM39618.1 - 0.16 12.8 2.4 0.36 11.7 2.4 1.6 1 1 0 1 1 1 0 Stm1 DUF5318 PF17249.2 CAM39619.1 - 0.12 12.1 1.1 5.7 6.7 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5318) FXMRP1_C_core PF12235.8 CAM39620.1 - 0.016 15.8 2.0 0.024 15.3 2.0 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal MCM PF00493.23 CAM39622.1 - 3.7e-93 310.7 0.0 6.5e-93 309.9 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CAM39622.1 - 4.2e-36 123.6 0.2 7.2e-36 122.8 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CAM39622.1 - 2.2e-27 95.3 0.1 5e-27 94.1 0.1 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CAM39622.1 - 3.1e-09 37.4 0.8 3.1e-09 37.4 0.8 3.2 3 1 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.21 CAM39622.1 - 1.2e-07 31.3 0.3 1.2e-05 24.8 0.0 2.7 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI MCM2_N PF12619.8 CAM39622.1 - 4.2e-06 27.1 23.1 4.2e-06 27.1 23.1 2.7 3 0 0 3 3 2 1 Mini-chromosome maintenance protein 2 AAA_5 PF07728.14 CAM39622.1 - 4.5e-06 26.7 0.0 9.9e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CAM39622.1 - 0.0008 19.3 0.0 0.0066 16.3 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 CAM39622.1 - 0.0072 16.1 0.0 0.026 14.3 0.0 1.9 1 0 0 1 1 1 1 AAA lid domain AAA PF00004.29 CAM39622.1 - 0.025 15.0 0.0 0.067 13.6 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CAM39622.1 - 0.1 12.3 0.0 0.44 10.2 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Ribonuc_red_lgC PF02867.15 CAM39626.1 - 2.5e-182 607.1 0.0 3.3e-182 606.7 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 CAM39626.1 - 1.2e-22 79.7 0.1 3.5e-22 78.2 0.1 1.9 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 CAM39626.1 - 9.8e-11 42.1 0.0 2.2e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 ATP cone domain Lebercilin PF15619.6 CAM39627.2 - 0.011 15.4 38.4 0.037 13.7 30.3 3.3 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease CEP63 PF17045.5 CAM39627.2 - 0.057 13.3 26.8 0.095 12.6 8.5 2.4 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa AAA_13 PF13166.6 CAM39627.2 - 0.1 11.2 10.1 0.19 10.3 10.1 1.5 1 0 0 1 1 1 0 AAA domain Prismane PF03063.20 CAM39627.2 - 0.24 10.0 4.7 0.34 9.5 4.7 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family DUF5499 PF17603.2 CAM39627.2 - 0.96 10.1 4.5 0.71 10.5 0.3 2.8 3 1 1 4 4 4 0 Family of unknown function (DUF5499) Prominin PF05478.11 CAM39627.2 - 4.7 5.1 10.5 1.9 6.4 6.9 1.8 1 1 1 2 2 2 0 Prominin FapA PF03961.13 CAM39627.2 - 8.7 4.8 13.4 30 3.1 12.2 2.0 1 1 0 1 1 1 0 Flagellar Assembly Protein A EF-hand_1 PF00036.32 CAM39628.1 - 1.8e-07 30.2 1.9 0.0084 15.6 0.1 2.9 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CAM39628.1 - 2.5e-07 30.1 0.5 0.011 15.6 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 CAM39628.1 - 3.9e-07 29.3 1.0 0.004 16.6 0.0 2.5 2 0 0 2 2 2 2 EF hand Dockerin_1 PF00404.18 CAM39628.1 - 2.7e-06 27.5 1.0 0.041 14.1 0.3 2.3 2 0 0 2 2 2 2 Dockerin type I domain EF-hand_7 PF13499.6 CAM39628.1 - 0.00013 22.3 0.1 0.0022 18.4 0.1 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CAM39628.1 - 0.0003 20.6 0.1 0.1 12.5 0.1 3.1 3 0 0 3 3 3 1 EF-hand domain pair FUN14 PF04930.15 CAM39628.1 - 0.02 15.3 0.5 0.048 14.1 0.5 1.6 1 1 1 2 2 2 0 FUN14 family adh_short PF00106.25 CAM39631.1 - 8.5e-14 51.5 0.0 4.9e-08 32.7 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CAM39631.1 - 6.5e-11 42.2 0.0 9.2e-06 25.4 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Tctex-1 PF03645.13 CAM39632.1 - 3.2e-24 85.1 0.3 3.7e-24 84.9 0.3 1.0 1 0 0 1 1 1 1 Tctex-1 family Ribosomal_S11 PF00411.19 CAM39633.1 - 3.3e-47 159.4 1.5 4.1e-47 159.1 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 LSM PF01423.22 CAM39634.1 - 0.0024 17.5 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.7 CAM39634.1 - 0.004 17.2 0.0 0.0067 16.5 0.0 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 CAM39634.1 - 0.026 14.7 0.1 0.051 13.7 0.1 1.6 1 1 0 1 1 1 0 Ataxin 2 SM domain DUF2642 PF10842.8 CAM39634.1 - 0.23 11.3 0.1 0.51 10.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2642) Serinc PF03348.15 CAM39636.1 - 1e-55 189.4 35.6 1.3e-54 185.8 35.6 1.9 1 1 0 1 1 1 1 Serine incorporator (Serinc) TctB PF07331.11 CAM39636.1 - 2.3 8.5 25.2 0.041 14.1 9.6 3.5 2 2 1 3 3 3 0 Tripartite tricarboxylate transporter TctB family Beta-lactamase PF00144.24 CAM39637.1 - 0.045 13.0 1.3 1.5 8.0 0.5 2.5 2 0 0 2 2 2 0 Beta-lactamase Ribosomal_S10 PF00338.22 CAM39638.1 - 7.1e-24 83.9 0.3 8.3e-24 83.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e PPR PF01535.20 CAM39639.1 - 0.00011 22.2 3.4 0.13 12.6 0.0 5.5 7 0 0 7 7 7 1 PPR repeat PPR_2 PF13041.6 CAM39639.1 - 0.00025 21.2 0.0 0.56 10.5 0.0 4.7 7 0 0 7 7 7 1 PPR repeat family PPR_long PF17177.4 CAM39639.1 - 0.049 13.0 0.4 0.77 9.1 0.0 2.8 3 0 0 3 3 3 0 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 CAM39639.1 - 0.054 13.6 0.0 1.4 9.0 0.0 2.8 2 0 0 2 2 2 0 Pentatricopeptide repeat domain TPR_14 PF13428.6 CAM39639.1 - 1.3 10.0 25.4 7.5 7.7 0.2 7.4 7 2 2 9 9 9 0 Tetratricopeptide repeat Ribosomal_S10 PF00338.22 CAM39640.1 - 7.1e-24 83.9 0.3 8.3e-24 83.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e FlxA PF14282.6 CAM39641.1 - 0.014 15.4 1.8 0.042 13.8 1.8 1.9 1 0 0 1 1 1 0 FlxA-like protein Hydant_A_N PF05378.13 CAM39641.1 - 0.4 10.4 2.5 0.37 10.5 0.5 1.9 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase N-terminal region Metallophos_2 PF12850.7 CAM39644.1 - 0.072 13.3 0.1 0.18 12.0 0.1 1.6 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain HMG_box_2 PF09011.10 CAM39645.2 - 0.001 19.6 3.2 0.18 12.4 0.1 2.7 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.19 CAM39645.2 - 0.17 12.3 0.9 11 6.5 0.1 2.5 2 0 0 2 2 2 0 HMG (high mobility group) box ATP-grasp_4 PF13535.6 CAM39646.1 - 4.5e-09 36.1 0.1 3e-07 30.2 0.1 2.4 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 CAM39646.1 - 1.8e-05 24.9 0.0 0.00018 21.6 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 CAM39646.1 - 2.2e-05 24.3 0.1 4.2e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.17 CAM39646.1 - 0.00023 20.8 0.0 0.017 14.7 0.0 2.3 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.6 CAM39646.1 - 0.0052 16.5 0.0 3 7.6 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ubiquitin PF00240.23 CAM39648.1 - 0.00011 21.8 0.1 0.00024 20.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family SP2 PF03014.14 CAM39648.1 - 0.039 12.4 3.5 0.063 11.7 3.5 1.2 1 0 0 1 1 1 0 Structural protein 2 DUF1287 PF06940.11 CAM39648.1 - 0.17 11.6 0.2 0.4 10.3 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1287) WD40 PF00400.32 CAM39649.1 - 3.8e-36 122.5 27.3 7.5e-05 23.4 0.0 10.3 10 0 0 10 10 10 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM39649.1 - 4.6e-14 52.5 0.1 0.0096 16.2 0.0 6.3 5 2 2 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CAM39649.1 - 9.8e-06 25.6 0.0 0.26 11.2 0.0 3.4 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CAM39649.1 - 0.0016 17.9 1.3 0.46 9.8 0.3 3.6 3 1 1 4 4 4 1 WD40-like domain PQQ_3 PF13570.6 CAM39649.1 - 0.0057 17.1 6.0 1e+02 3.6 0.0 6.7 7 0 0 7 7 7 0 PQQ-like domain Gmad1 PF10647.9 CAM39649.1 - 0.055 13.2 0.2 8.2 6.1 0.2 2.8 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain Nucleoporin_N PF08801.11 CAM39649.1 - 0.097 11.4 0.6 3.1 6.4 0.0 2.9 2 1 1 3 3 3 0 Nup133 N terminal like PD40 PF07676.12 CAM39649.1 - 0.14 12.1 0.1 14 5.8 0.0 3.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat WD40_3 PF15911.5 CAM39649.1 - 0.16 12.0 1.3 3.9 7.6 0.0 3.4 4 0 0 4 4 4 0 WD domain, G-beta repeat Amastin PF07344.11 CAM39651.1 - 4e-32 111.2 25.2 2.7e-22 79.3 4.8 2.6 2 1 1 3 3 3 2 Amastin surface glycoprotein ETF_alpha PF00766.19 CAM39652.1 - 1.4e-35 121.2 1.6 1.7e-35 120.9 0.1 1.9 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.21 CAM39652.1 - 3.1e-31 108.7 8.3 5e-31 108.0 8.3 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain AMP-binding PF00501.28 CAM39653.1 - 1.3e-50 172.2 0.3 4.2e-49 167.3 0.0 2.7 3 0 0 3 3 3 1 AMP-binding enzyme AMP-binding_C PF13193.6 CAM39653.1 - 1.5e-10 41.9 0.6 3.7e-10 40.7 0.6 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ATP-synt_C PF00137.21 CAM39655.1 - 8.3e-26 90.1 44.8 6.4e-19 68.0 13.6 3.0 3 0 0 3 3 3 2 ATP synthase subunit C LRR_6 PF13516.6 CAM39656.1 - 2.1e-08 33.6 10.8 0.041 13.9 0.0 6.4 6 0 0 6 6 6 3 Leucine Rich repeat LRR_4 PF12799.7 CAM39656.1 - 0.3 11.6 3.6 23 5.6 0.1 4.0 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) zf-AN1 PF01428.16 CAM39657.1 - 3.3e-09 36.7 8.2 5.2e-09 36.1 8.2 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 CAM39657.1 - 0.0002 21.6 3.0 0.00029 21.1 3.0 1.3 1 0 0 1 1 1 1 Tc5 transposase C-terminal domain PhnG PF06754.12 CAM39657.1 - 0.022 14.7 5.2 0.028 14.4 5.2 1.1 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnG Copine PF07002.16 CAM39659.1 - 4.9e-66 222.3 0.0 7.9e-66 221.6 0.0 1.3 1 0 0 1 1 1 1 Copine C2 PF00168.30 CAM39659.1 - 1.7e-26 92.5 0.0 1.7e-13 50.8 0.0 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 CAM39659.1 - 3.5e-05 24.0 0.0 5.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 CAM39659.1 - 0.018 15.3 0.0 0.03 14.6 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain HSP70 PF00012.20 CAM39660.1 - 4e-251 834.4 14.1 4.6e-251 834.2 14.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CAM39660.1 - 1e-20 73.9 0.7 3.5e-18 65.5 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 CAM39660.1 - 8.4e-05 22.4 0.0 0.00033 20.4 0.0 2.2 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 CAM39660.1 - 0.0052 16.1 0.2 0.039 13.2 0.1 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase DUF357 PF04010.13 CAM39660.1 - 0.16 12.1 0.2 27 4.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF357) Enolase_N PF03952.16 CAM39660.1 - 0.37 11.0 3.4 3.6 7.8 0.4 3.2 2 2 1 3 3 3 0 Enolase, N-terminal domain WWE PF02825.20 CAM39662.1 - 0.00088 19.8 0.0 0.0038 17.8 0.0 2.1 2 0 0 2 2 2 1 WWE domain BIV_Env PF05858.12 CAM39662.1 - 0.23 9.6 0.0 0.33 9.1 0.0 1.1 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) SGL PF08450.12 CAM39663.1 - 1e-39 136.6 0.0 3.1e-39 135.1 0.0 1.9 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region FAD_binding_1 PF00667.20 CAM39664.1 - 2.8e-36 125.2 0.0 4.4e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CAM39664.1 - 1.5e-33 116.0 0.5 6.1e-33 114.0 0.3 2.0 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 CAM39664.1 - 8.9e-13 48.8 0.0 3.1e-12 47.1 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain BILBO1_N PF18281.1 CAM39665.1 - 6.1e-27 93.9 0.1 6.1e-27 93.9 0.1 1.9 2 0 0 2 2 2 1 BILBO1 N-terminal domain DUF4201 PF13870.6 CAM39665.1 - 0.014 15.1 8.6 0.014 15.1 8.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Exonuc_VII_L PF02601.15 CAM39665.1 - 0.55 9.7 9.0 0.84 9.1 9.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMPIT PF07851.13 CAM39665.1 - 7.3 5.7 5.9 11 5.2 5.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein CwfJ_C_1 PF04677.15 CAM39666.1 - 0.096 12.6 0.3 0.18 11.6 0.3 1.5 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 DnaJ PF00226.31 CAM39667.1 - 2.7e-16 59.5 0.9 5.8e-16 58.4 0.9 1.6 1 0 0 1 1 1 1 DnaJ domain PDZ_6 PF17820.1 CAM39667.1 - 0.057 13.3 0.0 0.47 10.3 0.0 2.3 2 0 0 2 2 2 0 PDZ domain Biopterin_H PF00351.21 CAM39668.1 - 4.8e-130 433.4 0.0 6.5e-130 433.0 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase zf-C3HC4_2 PF13923.6 CAM39670.1 - 4.9e-07 29.5 11.0 8.5e-07 28.7 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CAM39670.1 - 1.7e-05 24.6 7.3 2.8e-05 24.0 7.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CAM39670.1 - 3.4e-05 23.6 8.4 5.8e-05 22.9 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CAM39670.1 - 3.9e-05 23.4 6.4 6.4e-05 22.7 6.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CAM39670.1 - 0.00015 21.7 11.2 0.0003 20.7 11.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 CAM39670.1 - 0.00024 21.4 9.9 0.0004 20.6 9.9 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CAM39670.1 - 0.0004 20.2 7.6 0.00073 19.3 7.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CAM39670.1 - 0.0015 18.7 12.6 0.0025 18.0 12.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Con-6 PF10346.9 CAM39670.1 - 0.076 13.1 0.8 0.23 11.5 0.2 2.1 2 0 0 2 2 2 0 Conidiation protein 6 Baculo_IE-1 PF05290.11 CAM39670.1 - 0.29 11.1 3.0 0.26 11.3 0.3 2.1 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) TF_Zn_Ribbon PF08271.12 CAM39670.1 - 0.47 10.0 3.9 2.5 7.7 0.3 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding zf-RING_6 PF14835.6 CAM39670.1 - 0.61 10.0 5.7 1.5 8.8 5.7 1.6 1 1 0 1 1 1 0 zf-RING of BARD1-type protein FAA_hydrolase_N PF09298.11 CAM39670.1 - 1.3 9.3 4.0 0.46 10.7 0.6 2.0 2 1 1 3 3 2 0 Fumarylacetoacetase N-terminal zf-HIT PF04438.16 CAM39670.1 - 1.5 8.7 7.2 1 9.3 3.0 2.2 2 0 0 2 2 2 0 HIT zinc finger DZR PF12773.7 CAM39670.1 - 3.7 7.7 7.5 19 5.4 7.7 1.9 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2 PF00096.26 CAM39670.1 - 4.5 7.9 0.0 4.5 7.9 0.0 2.9 3 0 0 3 3 2 0 Zinc finger, C2H2 type zf-RING_4 PF14570.6 CAM39670.1 - 5.9 6.8 8.0 12 5.8 8.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF4140 PF13600.6 CAM39670.1 - 8.7 6.9 6.5 65 4.1 0.2 3.0 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) BST2 PF16716.5 CAM39670.1 - 9.5 6.9 13.2 0.8 10.3 4.7 3.1 3 1 1 4 4 4 0 Bone marrow stromal antigen 2 DEAD PF00270.29 CAM39671.1 - 3.4e-42 144.2 0.0 6e-42 143.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAM39671.1 - 3.2e-25 88.6 0.0 1.5e-24 86.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CAM39671.1 - 1.1e-12 48.0 0.1 2.9e-12 46.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CAM39671.1 - 4.2e-08 33.4 0.0 1.1e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2753 PF10952.8 CAM39671.1 - 0.011 15.8 0.1 0.026 14.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2753) DUF3160 PF11369.8 CAM39671.1 - 0.043 12.3 0.1 0.077 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3160) UbiA PF01040.18 CAM39672.1 - 6.2e-37 127.3 19.7 6.4e-37 127.2 18.8 1.5 1 1 0 1 1 1 1 UbiA prenyltransferase family Hydrolase_3 PF08282.12 CAM39674.2 - 3.3e-28 99.1 0.0 2.3e-26 93.1 0.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CAM39674.2 - 1.5e-07 31.2 0.0 2.4e-06 27.3 0.0 2.2 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 CAM39674.2 - 0.13 12.5 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Orthoreo_P10 PF07204.11 CAM39675.1 - 0.051 13.5 0.5 1.7 8.6 0.0 2.8 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 NEMP PF10225.9 CAM39675.1 - 2.4 7.7 7.2 5.9 6.5 7.2 1.8 1 1 0 1 1 1 0 NEMP family Ank_2 PF12796.7 CAM39676.1 - 4.3e-44 149.0 0.0 2.6e-13 50.4 0.0 4.7 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CAM39676.1 - 4.2e-24 84.3 1.6 6.4e-09 35.9 0.0 4.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 CAM39676.1 - 1e-23 83.3 6.6 8.9e-09 35.7 0.1 5.2 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CAM39676.1 - 2.4e-23 79.7 1.4 0.00081 19.7 0.0 7.1 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 CAM39676.1 - 6.4e-19 67.5 3.0 1.7e-05 25.0 0.1 5.9 6 0 0 6 6 6 4 Ankyrin repeat DHHC PF01529.20 CAM39676.1 - 1.5e-08 34.8 2.4 1.9e-07 31.3 0.0 2.8 3 0 0 3 3 3 1 DHHC palmitoyltransferase Oest_recep PF02159.15 CAM39676.1 - 0.088 13.3 1.0 0.26 11.7 1.0 1.8 1 0 0 1 1 1 0 Oestrogen receptor Hydrolase_3 PF08282.12 CAM39678.1 - 1.8e-21 77.1 0.0 2.6e-20 73.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CAM39678.1 - 6.1e-07 29.2 0.0 8.7e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 CAM39678.1 - 0.084 13.2 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CAM39679.2 - 1.1e-36 127.0 0.0 9.4e-36 123.8 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CAM39679.2 - 4.8e-09 36.1 0.0 1.6e-06 27.8 0.0 2.4 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 CAM39679.2 - 0.0002 21.7 2.9 0.043 14.1 1.1 2.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF4438 PF14505.6 CAM39679.2 - 0.085 11.8 0.0 0.16 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4438) HAD PF12710.7 CAM39679.2 - 0.11 12.9 1.3 28 5.0 0.0 3.3 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase PSP1 PF04468.12 CAM39680.1 - 1.4e-27 95.8 0.3 3e-27 94.7 0.2 1.6 2 0 0 2 2 2 1 PSP1 C-terminal conserved region Hydrolase_3 PF08282.12 CAM39681.1 - 4.8e-52 177.2 0.0 6.6e-52 176.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CAM39681.1 - 1.1e-15 57.9 0.0 2.5e-07 30.5 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 CAM39681.1 - 1.5e-07 32.0 0.0 0.014 15.7 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 CAM39681.1 - 5e-05 23.8 0.3 0.031 14.7 0.0 2.9 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CAM39681.1 - 0.022 14.9 0.0 0.099 12.8 0.0 2.2 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Bmp PF02608.14 CAM39681.1 - 0.03 13.3 0.0 0.2 10.6 0.0 2.0 2 0 0 2 2 2 0 ABC transporter substrate-binding protein PnrA-like HAD_2 PF13419.6 CAM39681.1 - 0.067 13.3 0.1 14 5.7 0.0 2.6 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CAM39682.1 - 1.2e-50 172.7 0.0 1.4e-50 172.5 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CAM39682.1 - 7.6e-18 64.9 0.0 5.8e-09 35.8 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 CAM39682.1 - 5.8e-08 33.3 0.0 2.3e-07 31.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CAM39682.1 - 0.00051 20.5 0.3 2.3 8.6 0.0 3.4 2 1 2 4 4 4 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CAM39682.1 - 0.0058 16.7 0.0 0.026 14.6 0.0 2.2 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CAM39682.1 - 0.031 14.4 0.0 0.94 9.5 0.0 2.6 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CAM39683.1 - 2.2e-40 139.0 0.2 9.4e-23 81.2 0.1 3.7 3 1 0 3 3 3 3 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CAM39683.1 - 3.2e-15 56.3 0.1 2.6e-08 33.7 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 CAM39683.1 - 0.0011 19.3 0.0 0.022 15.0 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CAM39683.1 - 0.012 16.0 0.0 5.2 7.4 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Amastin PF07344.11 CAM39684.1 - 7.9e-52 175.2 6.1 1.1e-51 174.7 6.1 1.2 1 0 0 1 1 1 1 Amastin surface glycoprotein zf-CCCH_4 PF18044.1 CAM39686.1 - 7.3e-07 28.8 6.2 1.2e-06 28.2 6.2 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 CAM39686.1 - 7.4e-06 25.7 6.2 1.7e-05 24.6 5.6 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CAM39686.1 - 9.8e-05 22.3 6.6 0.00017 21.5 6.6 1.4 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 CAM39686.1 - 0.00088 20.0 1.2 0.0018 19.0 1.2 1.5 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 CAM39686.1 - 0.0018 18.7 6.6 0.0037 17.7 6.6 1.5 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger IMS PF00817.20 CAM39687.1 - 1.6e-34 119.1 0.1 2.8e-34 118.3 0.1 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 CAM39687.1 - 7.6e-11 42.7 0.5 1.9e-10 41.5 0.5 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 CAM39687.1 - 1.3e-05 25.3 0.0 2.9e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif Cas9_b_hairpin PF17893.1 CAM39687.1 - 0.048 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 CRISPR-associated endonuclease Cas9 beta-hairpin domain IMS PF00817.20 CAM39688.1 - 3.9e-31 108.1 0.1 8.1e-31 107.0 0.0 1.6 2 0 0 2 2 2 1 impB/mucB/samB family IMS PF00817.20 CAM39690.1 - 0.0025 17.8 0.2 1.4 8.9 0.2 3.6 1 1 0 1 1 1 1 impB/mucB/samB family AAA PF00004.29 CAM39692.1 - 3e-32 111.8 0.0 8.8e-29 100.6 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CAM39692.1 - 1.3e-12 48.4 1.5 1.5e-07 32.0 0.0 3.4 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 CAM39692.1 - 3.3e-08 33.9 0.0 9.7e-05 22.7 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.14 CAM39692.1 - 4.6e-08 33.2 0.0 3.9e-06 26.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 CAM39692.1 - 2e-07 30.9 0.0 0.00016 21.5 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.6 CAM39692.1 - 3.2e-07 30.6 0.0 0.00065 19.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain TniB PF05621.11 CAM39692.1 - 1.1e-06 28.2 0.0 0.003 17.0 0.0 3.3 3 0 0 3 3 3 2 Bacterial TniB protein AAA_14 PF13173.6 CAM39692.1 - 4.4e-06 26.8 0.0 2.1e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 CAM39692.1 - 7.3e-06 25.8 0.0 3.3e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 CAM39692.1 - 8.5e-06 26.1 0.0 0.0088 16.4 0.0 2.4 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.21 CAM39692.1 - 7.9e-05 22.1 0.0 0.0022 17.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 CAM39692.1 - 0.00018 21.1 0.0 0.018 14.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF815 PF05673.13 CAM39692.1 - 0.00023 20.4 0.0 0.0046 16.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 CAM39692.1 - 0.00086 19.5 0.0 0.025 14.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 CAM39692.1 - 0.0011 18.5 0.1 0.016 14.8 0.0 2.5 2 1 1 3 3 2 1 AAA domain AAA_24 PF13479.6 CAM39692.1 - 0.0012 18.6 0.0 0.013 15.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 CAM39692.1 - 0.0019 18.2 0.0 0.15 12.1 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 CAM39692.1 - 0.0028 16.9 0.0 0.0054 16.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 CAM39692.1 - 0.0037 17.8 0.0 0.054 14.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CAM39692.1 - 0.0063 16.4 0.0 0.055 13.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.6 CAM39692.1 - 0.0067 16.1 0.0 1.7 8.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain ATPase_2 PF01637.18 CAM39692.1 - 0.016 15.2 0.0 0.76 9.7 0.0 2.9 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea MCM PF00493.23 CAM39692.1 - 0.018 14.1 0.0 0.17 11.0 0.0 2.1 2 0 0 2 2 2 0 MCM P-loop domain T2SSE PF00437.20 CAM39692.1 - 0.019 14.0 0.0 1.5 7.8 0.0 2.8 2 1 0 2 2 2 0 Type II/IV secretion system protein AAA_28 PF13521.6 CAM39692.1 - 0.022 15.0 0.0 0.27 11.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CAM39692.1 - 0.024 15.1 0.0 0.13 12.8 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.26 CAM39692.1 - 0.027 14.2 0.0 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.11 CAM39692.1 - 0.036 13.9 0.0 0.077 12.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 CAM39692.1 - 0.039 13.4 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.17 CAM39692.1 - 0.046 12.8 0.0 0.11 11.6 0.0 1.5 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 CAM39692.1 - 0.055 13.2 0.0 0.33 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain CPT PF07931.12 CAM39692.1 - 0.063 13.1 0.1 2.2 8.1 0.0 3.0 3 1 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein Guanylate_kin PF00625.21 CAM39692.1 - 0.076 12.7 0.0 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 Guanylate kinase AAA_30 PF13604.6 CAM39692.1 - 0.078 12.7 0.0 0.38 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CAM39692.1 - 0.087 13.2 0.5 0.63 10.4 0.1 2.3 2 1 0 2 2 2 0 AAA domain Cytidylate_kin2 PF13189.6 CAM39692.1 - 0.088 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase-like family Syntaxin PF00804.25 CAM39693.1 - 1.2e-25 90.3 14.2 1.2e-25 90.3 14.2 1.3 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 CAM39693.1 - 4.9e-12 45.6 0.7 4.9e-12 45.6 0.7 2.6 2 0 0 2 2 2 1 SNARE domain ETRAMP PF09716.10 CAM39693.1 - 0.068 13.2 0.0 0.13 12.3 0.0 1.8 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) HECT_2 PF09814.9 CAM39693.1 - 0.081 11.8 3.0 0.12 11.3 3.0 1.1 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding TssN PF17555.2 CAM39693.1 - 0.11 11.8 1.6 0.13 11.6 0.5 1.7 2 0 0 2 2 2 0 Type VI secretion system, TssN KGK PF08872.10 CAM39693.1 - 0.12 12.9 3.0 0.6 10.6 0.5 2.4 1 1 1 2 2 2 0 KGK domain Syntaxin_2 PF14523.6 CAM39693.1 - 0.14 12.5 9.0 2.8 8.4 0.3 2.6 2 1 0 2 2 2 0 Syntaxin-like protein T2SSF PF00482.23 CAM39693.1 - 2.3 8.2 4.8 2.4 8.1 0.6 2.7 2 2 0 2 2 2 0 Type II secretion system (T2SS), protein F Syntaxin PF00804.25 CAM39694.1 - 1.6e-25 90.0 14.1 1.6e-25 90.0 14.1 1.4 2 0 0 2 2 2 1 Syntaxin HECT_2 PF09814.9 CAM39694.1 - 0.035 13.0 3.4 0.046 12.6 3.4 1.1 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding KGK PF08872.10 CAM39694.1 - 0.091 13.3 3.9 0.54 10.8 0.5 2.5 1 1 1 2 2 2 0 KGK domain DUF948 PF06103.11 CAM39694.1 - 0.44 10.8 4.5 8 6.8 0.8 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Syntaxin_2 PF14523.6 CAM39694.1 - 0.73 10.2 10.6 2.3 8.6 4.1 2.7 2 1 0 2 2 2 0 Syntaxin-like protein Fzo_mitofusin PF04799.13 CAM39694.1 - 1 8.9 8.7 0.5 9.9 0.2 2.6 1 1 2 3 3 3 0 fzo-like conserved region DUF423 PF04241.15 CAM39695.1 - 2.1e-17 63.1 1.5 3.2e-17 62.5 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF423) DUF423 PF04241.15 CAM39696.1 - 8.6e-18 64.3 0.5 1.2e-17 63.9 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF423) DUF423 PF04241.15 CAM39697.1 - 6.7e-21 74.3 3.3 1.1e-20 73.7 3.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF423) DUF3277 PF11681.8 CAM39697.1 - 0.11 12.4 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) MSP1_C PF07462.11 CAM39698.1 - 0.016 13.9 0.7 0.022 13.5 0.7 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus An_peroxidase PF03098.15 CAM39698.1 - 0.1 11.2 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Animal haem peroxidase NPV_P10 PF05531.12 CAM39699.1 - 0.27 11.7 14.0 0.31 11.5 0.6 5.0 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein DEAD PF00270.29 CAM39700.1 - 6.4e-45 153.1 0.0 2.7e-44 151.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAM39700.1 - 1.2e-31 109.3 0.1 9.7e-31 106.4 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAM39700.1 - 0.00045 20.3 0.0 0.003 17.6 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 CAM39700.1 - 0.0022 17.4 0.0 0.0049 16.3 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 CAM39700.1 - 0.095 11.9 0.1 0.13 11.4 0.1 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Tup_N PF08581.10 CAM39701.1 - 0.038 14.3 0.1 0.1 12.9 0.1 1.7 1 0 0 1 1 1 0 Tup N-terminal Coa1 PF08695.10 CAM39702.1 - 0.0022 17.7 0.0 0.0084 15.8 0.0 1.9 2 0 0 2 2 2 1 Cytochrome oxidase complex assembly protein 1 Abhydrolase_1 PF00561.20 CAM39704.1 - 1.3e-17 64.3 0.1 1.8e-15 57.3 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CAM39704.1 - 2.7e-16 59.6 0.0 4.5e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CAM39704.1 - 6.1e-11 43.3 0.3 7.9e-11 43.0 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CAM39704.1 - 1.1e-05 25.0 0.1 0.0038 16.7 0.0 2.8 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 CAM39704.1 - 0.0004 20.3 0.0 0.0051 16.6 0.0 2.2 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Ndr PF03096.14 CAM39704.1 - 0.00081 18.2 0.2 0.0018 17.0 0.1 1.5 1 1 0 1 1 1 1 Ndr family Peptidase_S15 PF02129.18 CAM39704.1 - 0.0012 18.5 0.0 0.14 11.7 0.0 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.13 CAM39704.1 - 0.0013 18.4 0.0 0.004 16.9 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 CAM39704.1 - 0.0015 18.1 0.0 0.021 14.4 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_4 PF08386.10 CAM39704.1 - 0.003 17.6 0.0 0.0056 16.8 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Esterase_phd PF10503.9 CAM39704.1 - 0.06 12.8 0.3 2.6 7.5 0.1 2.3 2 0 0 2 2 2 0 Esterase PHB depolymerase Esterase PF00756.20 CAM39704.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative esterase BAAT_C PF08840.11 CAM39704.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal TPP_enzyme_N PF02776.18 CAM39705.1 - 6e-13 48.8 0.9 3.4e-12 46.3 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 CAM39705.1 - 2e-10 40.7 5.1 3.4e-09 36.7 1.4 3.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PALP PF00291.25 CAM39705.1 - 0.025 14.0 0.5 0.099 12.0 0.5 1.8 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme Kelch_3 PF13415.6 CAM39706.1 - 6.9e-17 61.3 0.7 1.4e-05 25.2 0.0 4.9 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.6 CAM39706.1 - 9.3e-13 48.0 0.1 0.0002 21.5 0.0 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 CAM39706.1 - 7.1e-11 41.9 0.4 0.00012 22.0 0.0 3.7 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CAM39706.1 - 2.6e-10 40.0 0.8 8e-05 22.5 0.0 4.6 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 CAM39706.1 - 1.6e-09 37.2 3.4 0.00013 21.4 0.1 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 CAM39706.1 - 7.5e-09 35.2 3.2 0.0026 17.7 0.0 4.2 4 0 0 4 4 4 3 Kelch motif DUF2784 PF10861.8 CAM39706.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of Unknown function (DUF2784) Helicase_C_2 PF13307.6 CAM39707.2 - 3.1e-41 141.4 0.0 6.3e-41 140.4 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 CAM39707.2 - 2e-37 128.5 0.0 9.1e-37 126.4 0.0 2.0 2 0 0 2 2 2 1 DEAD_2 DEAD PF00270.29 CAM39707.2 - 0.0011 18.8 0.0 0.42 10.4 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 CAM39707.2 - 0.0015 18.5 0.0 0.53 10.3 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit HBB PF06777.11 CAM39707.2 - 0.2 11.3 0.0 0.4 10.3 0.0 1.4 1 0 0 1 1 1 0 Helical and beta-bridge domain DUF4510 PF14971.6 CAM39708.1 - 0.097 13.0 1.4 13 6.2 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4510) TruD PF01142.18 CAM39709.2 - 8.4e-31 107.2 0.0 8.2e-27 94.1 0.0 2.8 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) ALF PF03752.13 CAM39709.2 - 7.2 6.7 6.4 2.3 8.3 0.2 3.2 3 0 0 3 3 3 0 Short repeats of unknown function DUF3342 PF11822.8 CAM39711.1 - 4.1e-38 129.5 0.0 8.8e-38 128.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) Pkinase PF00069.25 CAM39713.1 - 0.02 14.3 0.0 2.8 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein kinase domain Pkinase_Tyr PF07714.17 CAM39713.1 - 0.13 11.5 0.0 2.7 7.2 0.0 2.2 2 0 0 2 2 2 0 Protein tyrosine kinase DUF5437 PF17505.2 CAM39714.1 - 2.4 8.3 5.4 0.46 10.5 0.3 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5437) Pkinase PF00069.25 CAM39715.1 - 3.5e-64 216.7 0.0 5e-64 216.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM39715.1 - 2.3e-34 118.9 0.0 3.5e-34 118.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Lipocalin_5 PF13924.6 CAM39715.1 - 2.6e-33 114.8 0.0 4.6e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 Lipocalin-like domain PX PF00787.24 CAM39715.1 - 8.7e-14 51.5 0.3 1.9e-13 50.4 0.3 1.5 1 0 0 1 1 1 1 PX domain Kinase-like PF14531.6 CAM39715.1 - 0.00044 19.7 0.0 0.00075 18.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like FYVE PF01363.21 CAM39715.1 - 0.00081 19.5 4.9 0.0025 17.9 4.9 1.9 1 0 0 1 1 1 1 FYVE zinc finger APH PF01636.23 CAM39715.1 - 0.0017 18.4 2.2 0.0095 15.9 0.3 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 CAM39715.1 - 0.065 12.6 0.1 0.15 11.4 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CAM39715.1 - 0.075 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 CAM39715.1 - 0.17 11.5 0.0 2.8 7.5 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RPN2_C PF18004.1 CAM39720.1 - 1.1e-29 103.5 0.0 1.8e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain HEAT_2 PF13646.6 CAM39720.1 - 5.2e-15 55.6 5.2 3.1e-12 46.7 0.0 4.8 4 1 0 5 5 5 1 HEAT repeats PC_rep PF01851.22 CAM39720.1 - 9.8e-15 54.2 8.6 0.39 11.3 0.0 8.1 7 0 0 7 7 7 4 Proteasome/cyclosome repeat Cnd1 PF12717.7 CAM39720.1 - 0.0053 16.8 3.7 0.42 10.6 0.1 3.2 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 TPR_14 PF13428.6 CAM39720.1 - 0.056 14.3 0.3 68 4.7 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 CAM39720.1 - 0.12 12.6 5.8 1.4e+02 3.1 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 CAM39720.1 - 2.8 8.3 8.7 8.2 6.8 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Methyltr_RsmB-F PF01189.17 CAM39721.1 - 3.5e-28 98.6 0.1 7.7e-15 55.1 0.1 2.3 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F ATP-grasp PF02222.22 CAM39721.1 - 0.11 12.1 0.0 0.49 9.9 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp domain Methyltransf_30 PF05430.11 CAM39722.1 - 0.025 14.5 0.0 0.067 13.1 0.0 1.7 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Pkinase PF00069.25 CAM39723.1 - 9.1e-13 48.2 0.0 8.6e-12 45.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM39723.1 - 0.00053 19.3 0.0 0.00095 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 CAM39723.1 - 0.0041 17.9 5.2 5.5 8.0 0.2 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat APH PF01636.23 CAM39723.1 - 0.025 14.5 3.7 0.029 14.3 0.1 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.22 CAM39723.1 - 0.24 11.0 0.0 0.83 9.2 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Sporozoite_P67 PF05642.11 CAM39723.1 - 6.7 4.7 7.7 15 3.5 7.7 1.6 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ArfGap PF01412.18 CAM39724.1 - 1.5e-11 44.4 0.0 2.3e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Topoisom_bac PF01131.20 CAM39725.2 - 4.6e-108 361.9 0.0 5.8e-108 361.5 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CAM39725.2 - 2.2e-18 66.4 0.0 3.9e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Toprim domain AAA PF00004.29 CAM39726.1 - 6.1e-31 107.6 0.0 9.3e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CAM39726.1 - 1.2e-05 25.7 0.0 2.9e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 CAM39726.1 - 2.5e-05 24.5 0.0 5.3e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CAM39726.1 - 4.2e-05 24.1 0.0 7.9e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CAM39726.1 - 4.7e-05 23.7 0.0 0.00011 22.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CAM39726.1 - 0.0011 18.9 0.0 0.0021 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Cytidylate_kin PF02224.18 CAM39726.1 - 0.0013 18.5 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 Cytidylate kinase RNA_helicase PF00910.22 CAM39726.1 - 0.0019 18.6 0.0 0.0046 17.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 CAM39726.1 - 0.0019 18.4 0.0 0.0037 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CAM39726.1 - 0.004 16.9 0.0 0.012 15.3 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 CAM39726.1 - 0.0055 16.7 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 CAM39726.1 - 0.0093 15.8 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CAM39726.1 - 0.017 14.9 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 CAM39726.1 - 0.022 14.3 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 CAM39726.1 - 0.033 13.9 0.0 0.096 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CAM39726.1 - 0.046 13.6 0.0 0.099 12.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 CAM39726.1 - 0.062 12.9 0.2 0.81 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 CAM39726.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_17 PF13207.6 CAM39726.1 - 0.11 12.9 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 CAM39726.1 - 0.12 11.8 0.0 0.34 10.3 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Mg_chelatase PF01078.21 CAM39726.1 - 0.15 11.4 0.0 0.41 10.0 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 CAM39726.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain PduV-EutP PF10662.9 CAM39726.1 - 0.22 11.3 0.0 0.64 9.8 0.0 1.8 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation Rep_fac-A_C PF08646.10 CAM39729.1 - 5.8e-41 139.7 0.6 1.8e-39 134.8 0.1 2.8 3 0 0 3 3 3 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 CAM39729.1 - 1.3e-22 79.6 2.2 8.8e-21 73.7 1.0 2.5 2 0 0 2 2 2 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 CAM39729.1 - 2.5e-12 46.6 0.9 7.2e-09 35.5 0.0 2.9 3 1 0 3 3 3 2 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 CAM39729.1 - 6.7e-07 29.2 0.0 3.1e-05 23.8 0.0 2.6 2 1 0 2 2 2 1 Cell division control protein 24, OB domain 3 tRNA_anti_2 PF13742.6 CAM39729.1 - 0.029 14.5 0.0 0.099 12.9 0.0 1.9 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain DZR PF12773.7 CAM39729.1 - 0.041 13.9 1.5 0.074 13.1 1.5 1.3 1 0 0 1 1 1 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 CAM39729.1 - 0.051 13.5 1.0 0.1 12.6 1.0 1.4 1 0 0 1 1 1 0 zinc-ribbons SHS2_Rpb7-N PF03876.17 CAM39729.1 - 0.094 13.1 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 zf_UBZ PF18439.1 CAM39729.1 - 0.098 12.3 2.5 2.9 7.6 0.3 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger OrfB_Zn_ribbon PF07282.11 CAM39729.1 - 0.62 10.0 2.9 1.3 9.0 2.9 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain SNF2_N PF00176.23 CAM39730.2 - 5.4e-57 193.1 0.0 1.1e-56 192.0 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CAM39730.2 - 9.1e-11 42.1 0.0 1.7e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 CAM39730.2 - 6.5e-10 38.7 10.1 6.5e-10 38.7 10.1 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CAM39730.2 - 3.3e-09 36.5 9.4 3.3e-09 36.5 9.4 3.0 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CAM39730.2 - 8.2e-09 35.7 10.3 8.2e-09 35.7 10.3 3.5 4 0 0 4 4 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CAM39730.2 - 7.8e-08 32.2 7.0 2.5e-07 30.6 7.0 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CAM39730.2 - 9.6e-08 31.8 10.6 9.6e-08 31.8 10.6 2.7 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CAM39730.2 - 1.1e-07 31.5 9.1 1.1e-07 31.5 9.1 2.9 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CAM39730.2 - 3.9e-06 26.7 8.9 3.9e-06 26.7 8.9 3.2 3 0 0 3 3 3 1 zinc-RING finger domain ResIII PF04851.15 CAM39730.2 - 5.7e-05 23.2 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_4 PF15227.6 CAM39730.2 - 0.00084 19.4 9.2 0.00084 19.4 9.2 2.6 3 0 0 3 3 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CAM39730.2 - 0.0013 18.9 5.6 0.0013 18.9 5.6 3.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain DEAD PF00270.29 CAM39730.2 - 0.0081 15.9 0.0 0.18 11.5 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-RING_11 PF17123.5 CAM39730.2 - 0.018 14.8 7.2 0.052 13.3 7.2 1.9 1 0 0 1 1 1 0 RING-like zinc finger zf-RanBP PF00641.18 CAM39730.2 - 0.033 13.5 11.9 0.062 12.6 2.0 3.4 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others zf-RING_6 PF14835.6 CAM39730.2 - 0.076 12.9 4.3 0.26 11.2 4.3 1.9 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DZR PF12773.7 CAM39730.2 - 1.8 8.6 22.1 2 8.5 0.3 3.7 3 0 0 3 3 3 0 Double zinc ribbon zf-RING_4 PF14570.6 CAM39730.2 - 6.5 6.6 13.3 0.4 10.5 7.0 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Aldolase_II PF00596.21 CAM39731.2 - 1.2e-40 139.5 0.0 1.3e-40 139.3 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Kinesin PF00225.23 CAM39732.2 - 1.7e-85 286.9 0.2 2.7e-85 286.2 0.2 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CAM39732.2 - 7.9e-36 123.2 0.0 5.8e-29 101.0 0.0 2.7 2 0 0 2 2 2 2 Microtubule binding DUF4530 PF15039.6 CAM39732.2 - 0.0096 16.1 4.4 4.1 7.6 2.2 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4530) bZIP_1 PF00170.21 CAM39732.2 - 0.16 12.1 3.0 4 7.6 0.3 2.6 2 0 0 2 2 2 0 bZIP transcription factor TLE_N PF03920.15 CAM39732.2 - 0.54 10.4 4.8 8.6 6.5 0.3 2.7 3 0 0 3 3 3 0 Groucho/TLE N-terminal Q-rich domain GAS PF13851.6 CAM39732.2 - 1.1 8.5 13.9 1.4 8.3 3.6 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding UPF0242 PF06785.11 CAM39732.2 - 5.7 7.0 19.3 0.23 11.5 4.6 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4586 PF15239.6 CAM39733.1 - 1.6e-38 133.7 2.4 2.4e-38 133.1 2.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) Methyltransf_16 PF10294.9 CAM39734.1 - 8.5e-14 51.7 0.8 6.5e-12 45.5 0.2 3.2 2 1 0 2 2 2 1 Lysine methyltransferase FAM86 PF14904.6 CAM39734.1 - 0.046 13.8 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function RIBIOP_C PF04950.12 CAM39735.1 - 1.7e-73 247.6 0.0 1.7e-73 247.6 0.0 1.8 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CAM39735.1 - 6e-22 77.5 0.0 2.2e-21 75.7 0.0 2.0 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 CAM39735.1 - 9.6e-05 22.7 0.0 0.00035 20.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 CAM39735.1 - 0.00028 21.3 0.1 0.00092 19.6 0.0 1.9 2 0 0 2 2 1 1 AAA ATPase domain AAA PF00004.29 CAM39735.1 - 0.0015 19.0 0.0 0.0039 17.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CAM39735.1 - 0.0021 17.8 0.0 0.0044 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 CAM39735.1 - 0.0023 18.0 0.1 0.0085 16.2 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CAM39735.1 - 0.0032 17.0 0.0 0.081 12.4 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 CAM39735.1 - 0.011 16.3 0.1 0.26 11.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CAM39735.1 - 0.012 16.2 0.1 0.053 14.0 0.0 2.1 2 0 0 2 2 1 0 ABC transporter AAA_5 PF07728.14 CAM39735.1 - 0.012 15.6 0.0 0.053 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) cobW PF02492.19 CAM39735.1 - 0.014 15.0 0.0 0.23 11.0 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 CAM39735.1 - 0.015 15.1 0.0 0.038 13.8 0.0 1.7 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 CAM39735.1 - 0.017 15.3 1.1 0.044 13.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CAM39735.1 - 0.017 15.0 0.1 0.035 14.0 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_19 PF13245.6 CAM39735.1 - 0.033 14.5 0.0 0.083 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CAM39735.1 - 0.045 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 CAM39735.1 - 0.054 12.7 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.6 CAM39735.1 - 0.09 12.5 0.0 0.31 10.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 CAM39735.1 - 0.11 12.1 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_17 PF13207.6 CAM39735.1 - 0.14 12.6 1.7 1.5 9.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 CAM39735.1 - 0.37 11.2 7.1 20 5.6 1.2 3.3 3 0 0 3 3 3 0 AAA domain DHHC PF01529.20 CAM39736.1 - 1.7e-22 79.9 12.9 1.7e-22 79.9 12.9 2.6 3 0 0 3 3 3 1 DHHC palmitoyltransferase IncD PF17628.2 CAM39736.1 - 0.057 13.2 2.1 0.1 12.3 2.1 1.3 1 0 0 1 1 1 0 Inclusion membrane protein D DnaJ PF00226.31 CAM39737.2 - 2.2e-07 30.9 0.0 4e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain BCIP PF13862.6 CAM39738.1 - 1.1e-31 110.3 0.0 1.6e-31 109.7 0.0 1.3 1 0 0 1 1 1 1 p21-C-terminal region-binding protein dsDNA_bind PF01984.20 CAM39739.1 - 6.6e-19 68.2 10.7 8.3e-19 67.9 10.7 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4748 PF15932.5 CAM39739.1 - 0.11 12.3 0.6 0.11 12.3 0.6 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4748) ATP-synt_G PF04718.15 CAM39739.1 - 1.3 9.9 4.6 11 7.0 1.6 2.0 1 1 1 2 2 2 0 Mitochondrial ATP synthase g subunit DUF2870 PF11069.8 CAM39739.1 - 3 8.3 7.6 1.6 9.2 4.8 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF2870) Ntox28 PF15605.6 CAM39740.1 - 0.0012 19.0 0.8 0.58 10.4 0.5 2.4 1 1 1 2 2 2 2 Bacterial toxin 28 DUF4648 PF15505.6 CAM39740.1 - 0.078 13.9 0.2 18 6.3 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4648) FtsK_SpoIIIE PF01580.18 CAM39740.1 - 0.13 11.6 1.1 8.4 5.7 0.1 2.1 1 1 1 2 2 2 0 FtsK/SpoIIIE family TPR_10 PF13374.6 CAM39740.1 - 0.17 11.8 1.4 16 5.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Zip PF02535.22 CAM39741.1 - 6e-45 153.9 9.8 7e-45 153.7 9.8 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter FliC_SP PF12613.8 CAM39741.1 - 0.32 11.5 5.0 3.5 8.2 0.0 2.6 2 0 0 2 2 2 0 Flagellin structural protein CorA PF01544.18 CAM39742.1 - 3.2e-09 36.5 2.7 9.3e-09 35.0 1.9 1.8 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein MAPEG PF01124.18 CAM39742.1 - 0.024 14.6 0.0 0.2 11.5 0.0 2.3 2 0 0 2 2 2 0 MAPEG family LRR_6 PF13516.6 CAM39744.1 - 3.6e-17 60.9 6.6 0.031 14.3 0.0 6.9 6 0 0 6 6 6 5 Leucine Rich repeat LRR_4 PF12799.7 CAM39744.1 - 1e-09 38.5 7.8 0.015 15.7 0.1 5.0 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM39744.1 - 0.00069 19.3 13.4 0.098 12.4 0.8 5.2 4 2 0 4 4 4 2 Leucine rich repeat PspA_IM30 PF04012.12 CAM39744.1 - 0.013 15.1 0.5 0.056 13.0 0.5 2.1 1 0 0 1 1 1 0 PspA/IM30 family LRR_1 PF00560.33 CAM39744.1 - 0.013 16.0 4.4 89 4.3 0.0 5.6 4 2 0 4 4 4 0 Leucine Rich Repeat DivIC PF04977.15 CAM39744.1 - 0.05 13.4 0.7 0.15 11.8 0.7 1.8 1 0 0 1 1 1 0 Septum formation initiator SlyX PF04102.12 CAM39744.1 - 0.11 13.1 0.5 0.38 11.4 0.5 2.0 1 0 0 1 1 1 0 SlyX Spectrin PF00435.21 CAM39744.1 - 0.13 12.7 0.4 0.35 11.4 0.4 1.6 1 0 0 1 1 1 0 Spectrin repeat GTP_EFTU PF00009.27 CAM39746.1 - 4.2e-41 140.6 0.0 7.5e-41 139.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 CAM39746.1 - 3.1e-19 68.9 0.0 5.7e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 CAM39746.1 - 3e-13 49.6 0.0 6.4e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus RF3_C PF16658.5 CAM39746.1 - 7.4e-07 29.0 0.0 1.5e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain GTP_EFTU_D2 PF03144.25 CAM39746.1 - 1.3e-06 28.7 0.0 3.5e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CAM39746.1 - 0.00058 19.9 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 CAM39746.1 - 0.0076 15.6 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 AIG1 family SRPRB PF09439.10 CAM39746.1 - 0.034 13.6 0.0 0.066 12.6 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 CAM39746.1 - 0.093 12.3 0.0 0.31 10.6 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B LacAB_rpiB PF02502.18 CAM39747.1 - 1.5e-51 174.1 0.6 1.7e-51 173.9 0.6 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Gly_rich_SFCGS PF14272.6 CAM39747.1 - 0.082 12.9 0.1 0.099 12.7 0.1 1.2 1 0 0 1 1 1 0 Glycine-rich SFCGS Pkinase PF00069.25 CAM39749.1 - 3.9e-54 183.8 0.0 9.1e-54 182.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM39749.1 - 2.1e-25 89.5 0.0 3.2e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAM39749.1 - 8.2e-05 21.5 0.0 0.0002 20.3 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CAM39749.1 - 0.0077 16.2 0.1 0.093 12.6 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CAM39749.1 - 0.019 14.3 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 CAM39749.1 - 0.036 13.6 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 CAM39749.1 - 0.051 12.9 0.0 0.096 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sporozoite_P67 PF05642.11 CAM39749.1 - 0.44 8.6 5.2 0.86 7.6 5.2 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen D123 PF07065.14 CAM39750.1 - 0.05 12.8 0.0 0.21 10.7 0.0 2.0 3 1 0 3 3 3 0 D123 zf-dskA_traR PF01258.17 CAM39750.1 - 0.081 12.9 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger Spc7 PF08317.11 CAM39751.1 - 2 7.2 45.8 10 4.9 24.7 2.7 1 1 1 2 2 2 0 Spc7 kinetochore protein GRIM-19 PF06212.12 CAM39752.1 - 7.2e-09 35.7 0.1 1e-08 35.2 0.1 1.2 1 0 0 1 1 1 1 GRIM-19 protein DPCD PF14913.6 CAM39753.1 - 1.8e-66 223.1 0.0 2.1e-66 222.9 0.0 1.0 1 0 0 1 1 1 1 DPCD protein family TilS_C PF11734.8 CAM39753.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 TilS substrate C-terminal domain AMP-binding PF00501.28 CAM39754.2 - 1.6e-28 99.5 0.0 4.1e-28 98.1 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme Ank_4 PF13637.6 CAM39754.2 - 2.1e-14 53.7 0.1 2.9e-09 37.3 0.0 2.9 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CAM39754.2 - 4.7e-13 49.5 0.2 4.8e-07 30.3 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CAM39754.2 - 6.5e-09 35.9 3.5 0.0019 18.5 0.1 4.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CAM39754.2 - 1.8e-08 34.0 1.3 0.033 14.7 0.0 5.4 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 CAM39754.2 - 9.2e-06 25.9 10.7 0.021 15.3 0.0 5.5 6 0 0 6 6 6 1 Ankyrin repeat PP-binding PF00550.25 CAM39754.2 - 0.015 15.6 0.0 0.039 14.3 0.0 1.7 1 0 0 1 1 1 0 Phosphopantetheine attachment site RNA_pol_L_2 PF13656.6 CAM39755.1 - 3.7e-23 81.1 0.0 5.4e-23 80.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CAM39755.1 - 7.4e-05 22.1 0.0 0.00014 21.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DEAD PF00270.29 CAM39757.1 - 5.3e-46 156.6 0.0 2.4e-45 154.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAM39757.1 - 2.9e-27 95.2 2.2 5.7e-27 94.3 0.1 2.4 3 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAM39757.1 - 4.9e-06 26.7 0.0 1.6e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CAM39757.1 - 0.00032 20.0 0.0 0.0005 19.4 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase PhoH PF02562.16 CAM39757.1 - 0.0024 17.4 0.1 1.3 8.4 0.0 3.2 3 0 0 3 3 3 1 PhoH-like protein T4SS-DNA_transf PF02534.14 CAM39757.1 - 0.0053 15.6 0.0 0.0089 14.9 0.0 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer CEP76-C2 PF15627.6 CAM39758.1 - 1.4e-37 128.7 0.0 2.3e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 CEP76 C2 domain Transglut_core PF01841.19 CAM39758.1 - 0.15 12.6 0.0 0.59 10.6 0.0 2.1 2 0 0 2 2 2 0 Transglutaminase-like superfamily C2 PF00168.30 CAM39758.1 - 0.17 12.2 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 C2 domain UPF0220 PF05255.11 CAM39759.1 - 2.7e-15 56.3 2.1 3e-15 56.1 2.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) LptF_LptG PF03739.14 CAM39759.1 - 0.41 9.4 10.9 0.21 10.4 2.7 2.0 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG GDPD PF03009.17 CAM39760.1 - 4.4e-18 66.0 0.0 3.1e-15 56.6 0.0 2.2 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family PI-PLC-X PF00388.19 CAM39760.1 - 0.075 12.6 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Cullin PF00888.22 CAM39761.1 - 4.3e-38 131.4 0.6 6.8e-38 130.7 0.6 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CAM39761.1 - 2e-09 37.3 0.0 1.3e-08 34.7 0.0 2.5 2 0 0 2 2 2 1 Cullin protein neddylation domain TrmB PF01978.19 CAM39761.1 - 0.013 15.4 1.5 0.11 12.5 0.1 2.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Penicillinase_R PF03965.16 CAM39761.1 - 0.024 15.0 0.1 0.15 12.4 0.0 2.4 2 0 0 2 2 2 0 Penicillinase repressor Cullin PF00888.22 CAM39762.1 - 7.6e-38 130.5 0.0 1.8e-37 129.3 0.0 1.5 1 1 0 1 1 1 1 Cullin family Penicillinase_R PF03965.16 CAM39762.1 - 0.0004 20.7 0.0 0.0017 18.7 0.0 2.2 1 0 0 1 1 1 1 Penicillinase repressor Cullin_Nedd8 PF10557.9 CAM39762.1 - 0.0062 16.6 0.0 0.018 15.1 0.0 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain HTH_20 PF12840.7 CAM39762.1 - 0.0072 16.4 0.3 4.7 7.3 0.1 3.3 4 0 0 4 4 4 2 Helix-turn-helix domain ANAPC2 PF08672.11 CAM39762.1 - 0.11 13.0 0.2 2.6 8.6 0.0 2.7 2 0 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 Dynein_light PF01221.18 CAM39763.1 - 8e-32 109.4 0.0 8.8e-32 109.3 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 TINF2_N PF14973.6 CAM39763.1 - 0.13 12.6 0.0 0.14 12.5 0.0 1.1 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus HhH-GPD PF00730.25 CAM39764.1 - 1.1e-16 61.3 0.0 5.4e-16 59.0 0.0 2.1 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 CAM39764.1 - 5.8e-13 48.8 0.0 1.4e-12 47.5 0.0 1.7 1 1 0 1 1 1 1 NUDIX domain HHH PF00633.23 CAM39764.1 - 1.6e-05 24.5 0.1 4.8e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 CAM39764.1 - 0.16 12.6 0.0 1 10.0 0.0 2.3 3 0 0 3 3 3 0 Helix-hairpin-helix domain HHH_2 PF12826.7 CAM39764.1 - 0.18 11.9 0.0 9.6 6.4 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif Kelch_4 PF13418.6 CAM39765.1 - 6.5e-08 32.5 0.0 5.5e-05 23.1 0.0 3.5 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CAM39765.1 - 5.7e-07 29.6 0.1 0.0009 19.5 0.0 3.9 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 CAM39765.1 - 5.9e-07 29.6 1.1 0.035 14.4 0.0 3.8 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CAM39765.1 - 3.4e-06 26.9 0.2 0.00015 21.6 0.0 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.15 CAM39765.1 - 0.00026 20.8 0.0 0.00026 20.8 0.0 3.4 4 0 0 4 4 4 1 Kelch motif APS-reductase_C PF12139.8 CAM39765.1 - 0.00082 19.5 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 Adenosine-5'-phosphosulfate reductase beta subunit Kelch_1 PF01344.25 CAM39765.1 - 0.006 16.1 0.0 0.44 10.2 0.0 3.0 2 0 0 2 2 2 1 Kelch motif Methyltransf_25 PF13649.6 CAM39766.1 - 9.1e-08 32.7 0.0 2.3e-07 31.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAM39766.1 - 3.9e-05 24.2 0.0 0.00013 22.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAM39766.1 - 0.00015 22.4 0.0 0.00026 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAM39766.1 - 0.017 15.0 0.0 0.022 14.6 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.18 CAM39766.1 - 0.1 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 YgbA_NO PF11756.8 CAM39766.1 - 0.11 12.9 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 Nitrous oxide-stimulated promoter CorA PF01544.18 CAM39767.1 - 0.23 10.8 1.7 0.4 9.9 1.7 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein ROS_MUCR PF05443.11 CAM39767.1 - 0.45 10.6 2.4 0.35 10.9 0.2 2.1 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein Sel1 PF08238.12 CAM39767.1 - 0.52 11.1 7.6 0.58 10.9 0.1 3.6 4 0 0 4 4 4 0 Sel1 repeat CortBP2 PF09727.9 CAM39769.1 - 0.0073 16.2 17.0 0.21 11.5 7.9 2.3 2 0 0 2 2 2 2 Cortactin-binding protein-2 Jnk-SapK_ap_N PF09744.9 CAM39769.1 - 0.042 14.1 16.6 0.84 9.9 0.5 2.4 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 SAP30_Sin3_bdg PF13867.6 CAM39769.1 - 0.13 12.6 0.6 0.31 11.4 0.6 1.5 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 MitMem_reg PF13012.6 CAM39769.1 - 0.61 10.5 3.1 11 6.5 0.0 2.5 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Exonuc_VII_L PF02601.15 CAM39769.1 - 2.1 7.8 10.9 2.4 7.6 5.3 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit Glyco_hydro_63 PF03200.16 CAM39770.1 - 8.9e-48 163.3 1.9 3.1e-32 112.0 0.2 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 CAM39770.1 - 3.1e-16 60.2 0.3 8.1e-16 58.8 0.3 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain CsiV PF10972.8 CAM39770.1 - 0.091 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Peptidoglycan-binding protein, CsiV PhosphMutase PF10143.9 CAM39772.1 - 9.9e-44 149.2 0.0 2.4e-43 148.0 0.0 1.7 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.18 CAM39772.1 - 5.8e-15 55.3 0.0 2.7e-14 53.1 0.0 1.9 1 1 0 1 1 1 1 Metalloenzyme superfamily GGACT PF06094.12 CAM39772.1 - 7.2e-10 39.5 0.0 2.1e-09 38.0 0.0 1.8 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Cyclin_N PF00134.23 CAM39773.1 - 0.00046 19.9 0.1 0.00092 19.0 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain PEX11 PF05648.14 CAM39775.1 - 0.00025 20.6 1.1 0.00034 20.2 1.1 1.3 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PEX11 PF05648.14 CAM39776.1 - 1.9e-21 76.5 0.9 3.4e-21 75.7 0.9 1.4 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) MOZ_SAS PF01853.18 CAM39777.1 - 8.8e-41 139.5 0.6 1.1e-21 77.3 0.6 3.1 2 1 1 3 3 3 3 MOZ/SAS family DNA_topoisoIV PF00521.20 CAM39778.1 - 1.5e-129 432.6 0.0 2.7e-129 431.8 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 CAM39778.1 - 1.4e-42 144.9 0.1 3.8e-42 143.6 0.1 1.8 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 CAM39778.1 - 1.2e-20 73.7 0.2 2.7e-20 72.6 0.2 1.5 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 CAM39778.1 - 8.5e-09 35.9 0.0 2.6e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 CAM39778.1 - 0.00038 20.6 0.0 0.001 19.3 0.0 1.7 1 0 0 1 1 1 1 Toprim domain DNA_gyraseB_C PF00986.21 CAM39778.1 - 0.0093 16.1 0.0 0.029 14.5 0.0 1.9 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus PBP1_TM PF14812.6 CAM39778.1 - 5.5 7.4 21.7 0.023 15.1 4.6 4.1 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Hexapep PF00132.24 CAM39779.1 - 1e-06 28.2 3.1 0.34 10.7 0.2 4.1 1 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 CAM39779.1 - 0.0086 15.7 0.0 0.071 12.7 0.0 2.3 2 1 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 CAM39779.1 - 0.012 16.0 0.3 0.043 14.2 0.3 1.9 1 1 0 1 1 1 0 MobA-like NTP transferase domain Fucokinase PF07959.12 CAM39779.1 - 0.081 11.9 0.2 0.16 10.8 0.2 1.5 1 0 0 1 1 1 0 L-fucokinase Hexapep_2 PF14602.6 CAM39779.1 - 1.5 8.6 6.9 5.9 6.7 2.2 3.7 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase Cep57_MT_bd PF06657.13 CAM39780.1 - 0.0015 18.9 0.1 0.0015 18.9 0.1 3.5 3 1 0 3 3 3 1 Centrosome microtubule-binding domain of Cep57 CENP-H PF05837.12 CAM39780.1 - 0.15 12.5 0.1 0.15 12.5 0.1 3.3 2 1 1 3 3 3 0 Centromere protein H (CENP-H) UPF0184 PF03670.13 CAM39780.1 - 1.9 8.9 6.8 0.65 10.4 2.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) PCI PF01399.27 CAM39781.1 - 6e-11 42.8 1.2 1.4e-10 41.6 1.2 1.7 1 0 0 1 1 1 1 PCI domain eIF3_N PF09440.10 CAM39781.1 - 8.2e-10 39.2 3.3 1.1e-09 38.8 1.6 2.1 2 1 0 2 2 2 1 eIF3 subunit 6 N terminal domain SUIM_assoc PF16619.5 CAM39782.2 - 0.07 13.2 0.3 0.07 13.2 0.3 2.8 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 CactinC_cactus PF09732.9 CAM39783.1 - 2.3e-37 127.7 1.5 3.9e-37 127.0 1.5 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein SHMT PF00464.19 CAM39786.1 - 7.6e-179 594.4 0.0 9.5e-179 594.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.19 CAM39786.1 - 0.0015 17.6 0.0 0.0025 16.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CAM39786.1 - 0.0087 15.4 0.0 0.029 13.6 0.0 2.0 1 1 0 1 1 1 1 Beta-eliminating lyase Sterol-sensing PF12349.8 CAM39787.2 - 0.0013 18.5 8.8 0.0013 18.5 8.8 3.1 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation Lectin_N PF03954.14 CAM39787.2 - 0.18 11.5 0.1 7.5 6.3 0.0 2.7 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain MCM PF00493.23 CAM39788.1 - 1.8e-91 305.2 0.2 2.7e-91 304.6 0.2 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CAM39788.1 - 7.9e-35 119.5 0.6 1.4e-34 118.6 0.6 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CAM39788.1 - 7.8e-22 77.5 4.8 1.3e-21 76.8 3.5 2.1 3 0 0 3 3 3 1 MCM AAA-lid domain MCM6_C PF18263.1 CAM39788.1 - 3.7e-09 36.8 0.0 7.8e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain Mg_chelatase PF01078.21 CAM39788.1 - 6.5e-07 28.9 0.0 3.8e-06 26.4 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CAM39788.1 - 0.00066 19.7 0.2 0.003 17.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MCM_N PF14551.6 CAM39788.1 - 0.0014 19.2 0.0 0.0036 17.9 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain AAA_3 PF07726.11 CAM39788.1 - 0.0062 16.4 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CAM39788.1 - 0.0087 15.8 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain DUF188 PF02639.14 CAM39788.1 - 0.21 11.2 0.9 13 5.4 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized BCR, YaiI/YqxD family COG1671 Mg_chelatase_C PF13335.6 CAM39788.1 - 0.96 10.1 4.6 28 5.4 0.6 2.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal WW PF00397.26 CAM39789.1 - 3.5e-09 36.6 0.9 7.7e-09 35.5 0.9 1.6 1 0 0 1 1 1 1 WW domain PGA_cap PF09587.10 CAM39789.1 - 5.2 6.4 14.5 0.039 13.4 1.3 3.5 3 0 0 3 3 3 0 Bacterial capsule synthesis protein PGA_cap Rft-1 PF04506.13 CAM39791.2 - 1.4e-44 152.7 12.7 6.7e-38 130.7 10.5 2.7 2 1 0 2 2 2 2 Rft protein 2-oxoacid_dh PF00198.23 CAM39792.1 - 4.9e-80 268.3 0.6 6.4e-80 267.9 0.6 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CAM39792.1 - 3.1e-20 71.8 1.8 5.2e-20 71.1 1.8 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CAM39792.1 - 2.2e-05 24.2 0.3 0.095 12.5 0.1 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like GCV_H PF01597.19 CAM39792.1 - 0.0016 18.3 0.8 0.0032 17.4 0.8 1.4 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD_D23 PF16576.5 CAM39792.1 - 0.029 13.6 0.1 0.22 10.7 0.0 2.0 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 CAM39792.1 - 0.046 14.4 0.5 1.5 9.6 0.0 2.5 1 1 1 2 2 2 0 HlyD family secretion protein ATP-synt_ab PF00006.25 CAM39793.1 - 5.6e-68 228.8 0.0 7.2e-68 228.4 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CAM39793.1 - 8.4e-14 51.9 0.7 1.7e-13 50.9 0.7 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain NTP_transferase PF00483.23 CAM39794.1 - 2e-05 24.3 0.0 0.00011 21.9 0.0 2.1 3 0 0 3 3 3 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 CAM39794.1 - 0.0037 17.6 0.0 0.039 14.3 0.0 2.5 1 1 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 CAM39794.1 - 0.0054 16.4 10.8 2.7 7.9 0.0 3.5 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 CAM39794.1 - 0.0065 15.4 0.1 0.01 14.8 0.1 1.2 1 0 0 1 1 1 1 L-fucokinase HTH_DeoR PF08220.12 CAM39794.1 - 0.14 11.9 0.0 0.45 10.3 0.0 1.9 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain DUF676 PF05057.14 CAM39795.1 - 1.3e-11 44.4 0.1 6e-11 42.3 0.1 1.9 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 CAM39795.1 - 0.0053 16.6 0.0 0.0082 16.0 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase ParA PF10609.9 CAM39797.1 - 6.7e-90 300.8 0.0 7.7e-90 300.6 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CAM39797.1 - 6.3e-16 58.6 0.0 2.4e-15 56.7 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CAM39797.1 - 1.6e-12 47.7 1.7 3e-10 40.3 0.2 2.1 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 CAM39797.1 - 4.2e-08 32.8 1.1 2.5e-07 30.3 1.1 1.9 1 1 0 1 1 1 1 ATPase MipZ VirC1 PF07015.11 CAM39797.1 - 3.6e-05 23.2 0.1 6.9e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 VirC1 protein Fer4_NifH PF00142.18 CAM39797.1 - 0.00011 21.7 0.0 0.00067 19.2 0.1 1.9 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 CAM39797.1 - 0.00056 19.2 0.4 0.0021 17.3 0.4 1.8 2 0 0 2 2 2 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 CAM39797.1 - 0.027 14.0 0.1 0.11 11.9 0.1 1.9 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ AAA_26 PF13500.6 CAM39797.1 - 0.094 12.5 0.2 14 5.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain DUF1611 PF07755.11 CAM39797.1 - 0.11 11.8 1.2 0.21 10.8 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_C) P-loop domain MeaB PF03308.16 CAM39797.1 - 0.16 10.9 0.4 0.25 10.3 0.4 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TFIIE-A_C PF11521.8 CAM39799.1 - 1.9 8.9 11.4 0.94 9.8 2.5 2.9 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha IF4E PF01652.18 CAM39800.1 - 2.5e-30 105.4 0.0 3.3e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E MRP-L20 PF12824.7 CAM39800.1 - 0.011 16.0 0.3 0.021 15.0 0.3 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 PAM2 PF07145.15 CAM39800.1 - 0.013 15.1 0.6 2.6 7.9 0.0 2.8 2 0 0 2 2 2 0 Ataxin-2 C-terminal region Acyl-CoA_dh_C PF12806.7 CAM39801.1 - 4.1e-25 88.3 1.5 1e-24 87.1 1.5 1.6 1 0 0 1 1 1 1 Acetyl-CoA dehydrogenase C-terminal like Acyl-CoA_dh_1 PF00441.24 CAM39801.1 - 4.2e-19 69.2 4.7 8.9e-18 64.9 4.7 2.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CAM39801.1 - 7.6e-19 67.7 0.0 1.6e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CAM39801.1 - 1.1e-12 48.5 0.0 2.4e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CAM39801.1 - 1e-05 25.8 0.1 2.6e-05 24.5 0.1 1.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain R3H PF01424.22 CAM39802.1 - 2.5e-10 40.2 0.3 5.6e-10 39.1 0.3 1.6 1 0 0 1 1 1 1 R3H domain PIF1 PF05970.14 CAM39803.2 - 8.1e-30 104.2 0.1 1.3e-24 87.0 0.0 3.9 4 0 0 4 4 4 2 PIF1-like helicase AAA_30 PF13604.6 CAM39803.2 - 1.1e-14 54.6 0.4 2.7e-14 53.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CAM39803.2 - 5.5e-06 26.8 0.2 2.8e-05 24.5 0.1 2.3 2 1 0 2 2 1 1 AAA domain UvrD_C_2 PF13538.6 CAM39803.2 - 1.8e-05 24.5 0.1 4.7e-05 23.1 0.1 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 CAM39803.2 - 5.4e-05 23.1 0.0 0.42 10.3 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 CAM39803.2 - 0.018 15.4 0.0 0.065 13.6 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain DUF853 PF05872.12 CAM39803.2 - 0.02 13.5 0.1 0.02 13.5 0.1 1.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) NTPase_1 PF03266.15 CAM39803.2 - 0.034 14.1 1.2 0.23 11.4 0.2 2.3 2 0 0 2 2 2 0 NTPase Mg_chelatase PF01078.21 CAM39803.2 - 0.04 13.3 0.0 0.094 12.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 CAM39803.2 - 0.051 12.6 0.1 0.39 9.7 0.0 2.4 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA PF00004.29 CAM39803.2 - 0.053 13.9 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 CAM39803.2 - 0.059 12.6 0.4 0.2 10.9 0.4 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MobB PF03205.14 CAM39803.2 - 0.072 13.0 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.22 CAM39803.2 - 0.1 11.8 0.1 0.19 10.9 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 CAM39803.2 - 0.14 12.1 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 NACHT domain DEAD PF00270.29 CAM39803.2 - 0.18 11.5 0.4 0.85 9.4 0.0 2.0 1 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_7 PF12775.7 CAM39803.2 - 0.21 11.1 0.1 0.42 10.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region SH3_13 PF18335.1 CAM39803.2 - 0.22 11.4 0.0 0.55 10.1 0.0 1.6 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain HEAT_2 PF13646.6 CAM39804.2 - 1e-10 41.8 17.8 4.6e-07 30.1 0.6 5.9 6 1 0 6 6 6 3 HEAT repeats HEAT PF02985.22 CAM39804.2 - 1.1e-08 34.6 0.7 0.0061 16.7 0.0 5.6 4 0 0 4 4 4 3 HEAT repeat TPR_2 PF07719.17 CAM39805.1 - 0.001 19.0 0.2 0.34 11.1 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat SET PF00856.28 CAM39805.1 - 0.0015 19.0 0.0 0.0031 17.9 0.0 1.5 1 0 0 1 1 1 1 SET domain Zn-ribbon_8 PF09723.10 CAM39805.1 - 0.0015 18.6 0.5 0.0042 17.2 0.5 1.8 1 0 0 1 1 1 1 Zinc ribbon domain zf-MYND PF01753.18 CAM39805.1 - 0.0015 18.5 8.5 0.0015 18.5 8.5 2.6 2 0 0 2 2 2 1 MYND finger HypA PF01155.19 CAM39805.1 - 0.093 12.8 0.7 0.79 9.8 0.0 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ribosomal_S17e PF00833.18 CAM39806.1 - 1.7e-49 166.8 3.7 2.1e-49 166.5 3.7 1.1 1 0 0 1 1 1 1 Ribosomal S17 Ribosomal_S17e PF00833.18 CAM39807.1 - 1.7e-49 166.8 3.7 2.1e-49 166.5 3.7 1.1 1 0 0 1 1 1 1 Ribosomal S17 SF3b1 PF08920.10 CAM39809.1 - 1.8e-07 31.7 0.1 4.8e-07 30.3 0.1 1.8 1 0 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 CAM39809.1 - 1e-05 25.8 20.0 0.11 12.9 4.4 7.0 5 2 3 8 8 8 2 HEAT repeats UME PF08064.13 CAM39809.1 - 0.00018 21.4 2.7 0.011 15.6 0.1 4.3 4 1 0 4 4 4 1 UME (NUC010) domain CLASP_N PF12348.8 CAM39809.1 - 0.0016 18.1 2.2 0.46 10.0 0.0 4.6 6 0 0 6 6 6 1 CLASP N terminal NUC173 PF08161.12 CAM39809.1 - 0.0029 17.3 5.3 0.33 10.6 0.0 4.6 5 2 1 6 6 6 1 NUC173 domain DRIM PF07539.12 CAM39809.1 - 0.0047 15.3 2.8 1.1 7.5 0.6 2.9 2 1 0 2 2 2 2 Down-regulated in metastasis CTD PF12815.7 CAM39809.1 - 0.053 14.1 6.3 0.056 14.0 4.2 2.0 1 1 1 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Adaptin_N PF01602.20 CAM39809.1 - 0.076 11.6 0.7 5 5.6 0.0 2.7 2 1 0 2 2 2 0 Adaptin N terminal region DHO_dh PF01180.21 CAM39809.1 - 0.097 11.9 0.1 0.19 10.9 0.1 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase HEAT_EZ PF13513.6 CAM39809.1 - 0.34 11.5 21.7 4.8 7.8 0.0 7.6 8 1 1 9 9 8 0 HEAT-like repeat HEAT PF02985.22 CAM39809.1 - 2.5 8.6 0.0 2.5 8.6 0.0 6.4 7 0 0 7 7 6 0 HEAT repeat LRR_4 PF12799.7 CAM39810.1 - 1.7e-11 44.2 7.2 4.2e-05 23.8 0.6 4.3 2 2 2 4 4 4 3 Leucine Rich repeats (2 copies) IQ PF00612.27 CAM39810.1 - 2.4e-09 36.1 10.2 1.9e-05 24.0 2.3 3.0 2 0 0 2 2 2 2 IQ calmodulin-binding motif LRR_8 PF13855.6 CAM39810.1 - 1.5e-07 31.0 14.3 0.0016 18.1 0.2 4.2 3 1 2 5 5 5 4 Leucine rich repeat LRR_9 PF14580.6 CAM39810.1 - 0.0011 18.6 2.1 0.022 14.2 0.7 2.6 3 0 0 3 3 3 1 Leucine-rich repeat LRR_1 PF00560.33 CAM39810.1 - 0.0039 17.5 3.8 37 5.4 0.0 4.9 4 0 0 4 4 4 0 Leucine Rich Repeat Glycogen_syn PF05693.13 CAM39810.1 - 0.14 10.7 0.0 0.24 9.9 0.0 1.2 1 0 0 1 1 1 0 Glycogen synthase LRR_6 PF13516.6 CAM39810.1 - 0.18 11.9 9.3 32 4.9 0.1 5.7 7 0 0 7 7 7 0 Leucine Rich repeat ADP_ribosyl_GH PF03747.14 CAM39811.1 - 8.2e-11 42.2 0.4 1.4e-06 28.3 0.7 2.7 2 1 0 2 2 2 2 ADP-ribosylglycohydrolase IQ PF00612.27 CAM39812.1 - 1.9e-23 80.0 86.8 4.7e-05 22.8 2.0 14.4 14 0 0 14 14 14 12 IQ calmodulin-binding motif Fis1_TPR_C PF14853.6 CAM39812.1 - 0.099 12.7 0.0 0.3 11.2 0.0 1.8 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Adaptin_N PF01602.20 CAM39813.2 - 5.1e-71 239.8 15.5 6.2e-71 239.5 15.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 CAM39813.2 - 6.1e-31 107.6 0.1 1.2e-30 106.6 0.1 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 CAM39813.2 - 2.7e-21 75.9 0.0 5.8e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 CAM39813.2 - 3.6e-11 43.3 1.4 2.3e-06 27.9 0.0 4.5 3 2 1 4 4 4 2 HEAT repeats Cnd1 PF12717.7 CAM39813.2 - 0.00021 21.3 12.0 0.0021 18.1 0.3 4.2 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CAM39813.2 - 0.00094 19.2 7.3 5.9 7.4 0.1 5.2 5 0 0 5 5 5 2 HEAT repeat MoaC PF01967.21 CAM39815.2 - 7.6e-21 74.6 0.0 2e-20 73.3 0.0 1.7 2 0 0 2 2 2 1 MoaC family His_Phos_2 PF00328.22 CAM39816.1 - 1.6e-09 37.7 0.4 2.9e-06 26.9 0.0 2.9 2 1 1 3 3 3 2 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.22 CAM39816.1 - 0.049 13.3 0.0 0.23 11.2 0.0 2.1 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) SelR PF01641.18 CAM39817.1 - 1.4e-38 131.7 0.0 1.6e-38 131.5 0.0 1.0 1 0 0 1 1 1 1 SelR domain zinc_ribbon_10 PF10058.9 CAM39817.1 - 0.0047 16.6 0.3 0.29 10.9 0.0 2.5 2 0 0 2 2 2 1 Predicted integral membrane zinc-ribbon metal-binding protein FYVE PF01363.21 CAM39817.1 - 0.036 14.2 1.1 0.067 13.3 1.1 1.4 1 0 0 1 1 1 0 FYVE zinc finger Yippee-Mis18 PF03226.14 CAM39817.1 - 0.056 13.7 1.2 0.62 10.3 1.2 2.2 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf_C2HC_14 PF18574.1 CAM39817.1 - 0.1 12.4 1.5 0.11 12.3 0.1 1.8 2 0 0 2 2 2 0 C2HC Zing finger domain Metallophos PF00149.28 CAM39818.1 - 9.9e-34 117.6 0.1 1.2e-33 117.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase VitD-bind_III PF09164.10 CAM39818.1 - 0.14 12.1 0.9 0.31 11.0 0.9 1.5 1 0 0 1 1 1 0 Vitamin D binding protein, domain III COX15-CtaA PF02628.15 CAM39819.1 - 1.4e-102 343.1 9.7 1.8e-102 342.8 9.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein 2OG-FeII_Oxy_2 PF13532.6 CAM39822.1 - 0.0017 18.6 0.0 0.0023 18.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily APG12 PF04110.13 CAM39823.1 - 0.049 14.0 0.0 0.26 11.7 0.0 2.0 1 1 1 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DNA_processg_A PF02481.15 CAM39823.1 - 0.1 11.8 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 DNA recombination-mediator protein A DUF179 PF02622.15 CAM39824.2 - 2.5e-06 27.6 0.0 7.3e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized ACR, COG1678 WD40 PF00400.32 CAM39825.1 - 2.2e-45 151.7 18.9 1.2e-07 32.3 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM39825.1 - 9.7e-13 48.2 0.4 0.016 15.5 0.0 4.4 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CAM39825.1 - 2.3e-08 33.2 3.8 0.022 13.4 0.0 3.9 2 2 2 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.11 CAM39825.1 - 2.8e-06 27.3 0.0 0.054 13.4 0.0 3.3 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CAM39825.1 - 9.3e-05 21.5 1.5 0.012 14.6 0.6 3.6 1 1 3 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 CAM39825.1 - 0.00033 20.5 0.2 1.6 8.8 0.1 4.8 5 1 0 5 5 5 1 WD40-like Beta Propeller Repeat WD40_like PF17005.5 CAM39825.1 - 0.0093 15.3 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 WD40-like domain Cytochrom_D1 PF02239.16 CAM39825.1 - 0.018 13.6 0.0 1.3 7.5 0.0 2.4 2 1 0 2 2 2 0 Cytochrome D1 heme domain PQQ_2 PF13360.6 CAM39825.1 - 0.02 14.5 0.1 0.1 12.2 0.0 2.1 1 1 0 2 2 2 0 PQQ-like domain Coatomer_WDAD PF04053.14 CAM39825.1 - 0.17 10.9 0.0 0.51 9.3 0.0 1.6 1 1 1 2 2 2 0 Coatomer WD associated region GCP_C_terminal PF04130.13 CAM39826.1 - 2.3e-40 139.0 8.9 4.8e-40 137.9 8.9 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 CAM39826.1 - 1.1e-31 110.6 1.2 1.9e-31 109.8 0.0 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal HSP70 PF00012.20 CAM39827.2 - 1.4e-44 152.3 0.3 1.7e-44 152.0 0.3 1.0 1 0 0 1 1 1 1 Hsp70 protein DUF4854 PF16146.5 CAM39827.2 - 0.01 16.1 3.9 0.015 15.6 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4854) Tape_meas_lam_C PF09718.10 CAM39827.2 - 0.14 12.3 0.9 0.43 10.7 0.9 1.8 1 1 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) HSP70 PF00012.20 CAM39828.1 - 4.2e-123 411.6 0.7 4.7e-123 411.5 0.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CAM39828.1 - 2e-11 43.3 0.1 7.1e-10 38.2 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein HSP70 PF00012.20 CAM39829.1 - 4.5e-262 870.6 3.6 5e-262 870.4 3.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CAM39829.1 - 1.7e-13 50.1 0.0 2.3e-12 46.4 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 CAM39829.1 - 0.011 15.5 0.1 0.066 12.9 0.0 2.2 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 CAM39829.1 - 0.078 12.0 0.5 2 7.3 0.2 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain DUF4854 PF16146.5 CAM39829.1 - 0.11 12.8 5.6 0.086 13.2 3.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4854) Beta-lactamase PF00144.24 CAM39831.2 - 9e-12 44.9 0.1 2.5e-11 43.4 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase HSP70 PF00012.20 CAM39833.1 - 9.5e-193 641.6 5.5 1.1e-192 641.4 5.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CAM39833.1 - 3.3e-18 65.6 0.7 1.4e-14 53.6 0.1 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 CAM39833.1 - 0.00027 21.3 4.6 0.029 14.8 0.0 3.4 3 2 0 3 3 3 2 Cell division protein FtsA BcrAD_BadFG PF01869.20 CAM39833.1 - 0.0018 17.8 0.3 0.26 10.7 0.0 2.7 2 1 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Raco_middle PF17651.1 CAM39833.1 - 0.23 11.1 1.1 1.1 8.9 0.0 2.6 3 0 0 3 3 3 0 RACo middle region ATG16 PF08614.11 CAM39835.2 - 1.5 9.0 7.4 2.1 8.5 6.0 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) F-box PF00646.33 CAM39836.1 - 0.032 14.1 0.0 0.086 12.7 0.0 1.7 1 0 0 1 1 1 0 F-box domain Ribosomal_60s PF00428.19 CAM39836.1 - 1.4 9.6 5.4 0.71 10.5 2.4 2.2 2 1 0 2 2 2 0 60s Acidic ribosomal protein Ldh_1_N PF00056.23 CAM39837.1 - 2.4e-32 112.0 0.1 3.6e-32 111.4 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CAM39837.1 - 3.1e-27 95.5 0.0 4.9e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Sigma70_r4_2 PF08281.12 CAM39838.1 - 0.21 11.3 0.9 6.9 6.4 0.0 2.9 3 0 0 3 3 3 0 Sigma-70, region 4 AAA_6 PF12774.7 CAM39839.2 - 9.5e-150 498.1 0.0 3.2e-149 496.3 0.0 2.0 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CAM39839.2 - 4.9e-105 351.9 0.2 4.9e-105 351.9 0.2 3.8 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 CAM39839.2 - 1.1e-100 336.2 0.0 3.9e-100 334.5 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CAM39839.2 - 9.6e-81 271.3 0.0 2.7e-79 266.6 0.0 3.6 4 0 0 4 4 4 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 CAM39839.2 - 1.3e-75 253.3 0.1 1.3e-75 253.3 0.1 2.6 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 CAM39839.2 - 3e-71 238.7 0.5 6.2e-65 218.1 0.0 4.1 4 0 0 4 4 4 3 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CAM39839.2 - 8.2e-55 185.1 0.0 2.1e-54 183.8 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CAM39839.2 - 3.3e-43 146.6 0.0 1.2e-41 141.5 0.0 3.5 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 CAM39839.2 - 2.3e-40 138.7 10.1 4.6e-40 137.7 10.1 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 CAM39839.2 - 3.6e-25 88.5 0.0 1.5e-24 86.6 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CAM39839.2 - 4.6e-25 88.2 0.0 4.6e-07 29.9 0.0 6.4 6 1 0 6 6 6 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 CAM39839.2 - 9.7e-12 45.0 0.1 3.3e-11 43.3 0.0 2.0 2 0 0 2 2 1 1 AAA+ lid domain AAA PF00004.29 CAM39839.2 - 1.6e-09 38.3 0.6 0.047 14.1 0.0 5.2 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CAM39839.2 - 9e-06 26.2 10.6 3.3 8.1 0.0 7.5 7 1 1 8 8 6 2 AAA ATPase domain AAA_18 PF13238.6 CAM39839.2 - 2.7e-05 24.7 0.0 0.083 13.4 0.0 4.2 4 0 0 4 4 3 1 AAA domain AAA_22 PF13401.6 CAM39839.2 - 3.2e-05 24.2 4.8 3 8.1 0.0 5.9 5 0 0 5 5 4 1 AAA domain DUF853 PF05872.12 CAM39839.2 - 0.0012 17.5 0.5 0.051 12.2 0.1 2.6 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF853) Sigma54_activat PF00158.26 CAM39839.2 - 0.0013 18.4 0.4 0.58 9.8 0.0 3.9 4 0 0 4 4 4 1 Sigma-54 interaction domain RNA_helicase PF00910.22 CAM39839.2 - 0.0017 18.7 0.0 0.38 11.2 0.0 4.0 3 0 0 3 3 3 1 RNA helicase AAA_14 PF13173.6 CAM39839.2 - 0.0025 17.9 0.0 1.7 8.6 0.0 3.3 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 CAM39839.2 - 0.023 14.7 0.9 1 9.3 0.0 3.5 4 0 0 4 4 3 0 Type III restriction enzyme, res subunit NACHT PF05729.12 CAM39839.2 - 0.043 13.7 1.7 9.9 6.0 0.0 4.2 4 0 0 4 4 4 0 NACHT domain AAA_33 PF13671.6 CAM39839.2 - 0.11 12.6 1.7 61 3.8 0.0 4.5 4 0 0 4 4 3 0 AAA domain AAA_19 PF13245.6 CAM39839.2 - 0.48 10.8 3.6 59 4.0 0.0 4.2 4 0 0 4 4 3 0 AAA domain FNIP_M PF14637.6 CAM39839.2 - 0.62 10.0 3.5 3.1 7.8 0.4 3.0 3 0 0 3 3 2 0 Folliculin-interacting protein middle domain SRP54 PF00448.22 CAM39839.2 - 2.1 7.9 5.1 21 4.7 0.1 3.9 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain Dor1 PF04124.12 CAM39841.1 - 9.3e-24 83.7 3.3 1.2e-23 83.4 3.3 1.1 1 0 0 1 1 1 1 Dor1-like family Exo84_C PF16528.5 CAM39841.1 - 1.4e-05 25.0 0.1 3.2e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Exocyst component 84 C-terminal ELFV_dehydrog PF00208.21 CAM39842.1 - 2.1e-85 286.3 3.3 2.9e-85 285.9 3.3 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 CAM39842.1 - 1.2e-50 170.7 0.0 2.7e-50 169.6 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 CAM39842.1 - 0.0017 18.8 0.1 0.0032 17.9 0.1 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Na_sulph_symp PF00939.19 CAM39844.1 - 3.5e-16 59.3 48.6 1.7e-15 57.0 48.6 2.5 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 CAM39844.1 - 1e-15 57.7 49.2 1e-15 57.7 49.2 1.8 1 1 1 2 2 2 1 Citrate transporter SPX PF03105.19 CAM39844.1 - 1.3e-06 28.6 8.0 3.5e-06 27.2 0.5 2.5 1 1 2 3 3 3 2 SPX domain zf-CCCH_4 PF18044.1 CAM39846.1 - 0.014 15.1 0.6 0.014 15.1 0.6 2.8 2 1 1 3 3 3 0 CCCH-type zinc finger zf-CCCH PF00642.24 CAM39846.1 - 0.32 11.0 8.1 3.7 7.6 0.3 2.6 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CAM39846.1 - 2.2 8.4 9.0 0.18 11.9 2.3 2.3 2 0 0 2 2 2 0 Zinc finger domain WD40 PF00400.32 CAM39847.1 - 0.028 15.3 12.0 1.7 9.6 1.3 5.0 5 0 0 5 5 5 0 WD domain, G-beta repeat DUF2828 PF11443.8 CAM39847.1 - 0.28 9.2 0.0 5.3 5.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) dCache_2 PF08269.11 CAM39851.1 - 0.099 11.8 0.8 0.17 11.0 0.0 1.7 1 1 1 2 2 2 0 Cache domain Pkinase PF00069.25 CAM39852.2 - 1.7e-46 158.7 0.0 2.1e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM39852.2 - 9e-28 97.3 0.0 1.1e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAM39852.2 - 5.9e-05 22.0 0.0 7.9e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CAM39852.2 - 0.00041 19.8 0.0 0.00067 19.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like SMRP1 PF15181.6 CAM39852.2 - 0.081 12.5 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Spermatid-specific manchette-related protein 1 Acetyltransf_1 PF00583.25 CAM39853.1 - 8.4e-12 45.4 0.0 9.9e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CAM39853.1 - 1.2e-07 31.7 0.0 1.5e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CAM39853.1 - 1.1e-06 28.9 0.0 1.6e-06 28.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CAM39853.1 - 0.029 14.4 0.0 0.044 13.9 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain CARD PF00619.21 CAM39853.1 - 0.042 13.9 0.1 0.11 12.5 0.1 1.6 2 0 0 2 2 2 0 Caspase recruitment domain Acetyltransf_CG PF14542.6 CAM39853.1 - 0.062 13.4 0.0 0.092 12.9 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase NnrU PF07298.11 CAM39854.2 - 0.11 12.0 8.0 22 4.4 0.0 4.8 5 0 0 5 5 5 0 NnrU protein PHO4 PF01384.20 CAM39855.1 - 7.4e-105 350.7 16.3 9.4e-105 350.4 16.3 1.1 1 0 0 1 1 1 1 Phosphate transporter family Exo_endo_phos PF03372.23 CAM39856.1 - 0.0077 15.8 3.0 1.3 8.4 0.4 2.9 2 1 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family ECH_1 PF00378.20 CAM39858.1 - 4.5e-36 124.4 0.0 5.5e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CAM39858.1 - 4.2e-10 39.6 0.0 6.1e-10 39.1 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase SPT16 PF08644.11 CAM39859.1 - 1.4e-31 109.7 0.0 4.6e-31 108.0 0.0 1.9 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 CAM39859.1 - 2.2e-13 50.4 0.0 4.4e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 CAM39859.1 - 1.7e-08 34.7 0.4 4.9e-08 33.3 0.0 1.9 2 0 0 2 2 2 1 Histone chaperone Rttp106-like CoaE PF01121.20 CAM39859.1 - 0.071 12.8 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase KR PF08659.10 CAM39859.1 - 0.091 12.7 0.6 0.19 11.6 0.6 1.5 1 0 0 1 1 1 0 KR domain SAPS PF04499.15 CAM39859.1 - 0.14 10.9 1.8 0.25 10.1 1.8 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 CAM39859.1 - 1.8 6.8 13.9 3.8 5.7 13.9 1.5 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 CAM39859.1 - 3.7 5.6 17.9 6.3 4.9 17.9 1.3 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.11 CAM39859.1 - 3.7 5.5 5.8 5.8 4.9 5.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ribosomal_L3 PF00297.22 CAM39860.1 - 9.3e-08 31.4 0.1 1.5e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L3 TPR_2 PF07719.17 CAM39860.1 - 0.19 12.0 0.7 0.51 10.6 0.7 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat GSP_synth PF03738.14 CAM39861.1 - 0.057 12.6 0.0 0.099 11.8 0.0 1.3 1 0 0 1 1 1 0 Glutathionylspermidine synthase preATP-grasp tRNA-synt_1b PF00579.25 CAM39863.1 - 4.9e-19 68.8 0.0 1.4e-18 67.2 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) ATG11 PF10377.9 CAM39863.1 - 0.16 12.1 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 Autophagy-related protein 11 SNARE PF05739.19 CAM39864.1 - 4.3e-06 26.6 0.7 1.2e-05 25.2 0.7 1.8 1 0 0 1 1 1 1 SNARE domain DUF1664 PF07889.12 CAM39864.1 - 0.0042 17.1 3.4 0.67 10.0 0.2 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) Synaptobrevin PF00957.21 CAM39864.1 - 0.038 13.8 4.3 0.059 13.2 0.6 2.3 2 0 0 2 2 2 0 Synaptobrevin Prominin PF05478.11 CAM39864.1 - 0.041 11.8 4.4 0.063 11.2 4.4 1.3 1 1 0 1 1 1 0 Prominin BLOC1S3 PF15753.5 CAM39864.1 - 0.062 13.4 0.7 0.062 13.4 0.7 2.9 1 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 RmuC PF02646.16 CAM39864.1 - 0.34 10.0 7.1 0.084 12.0 0.9 2.6 2 1 1 3 3 3 0 RmuC family DUF948 PF06103.11 CAM39864.1 - 0.42 10.9 2.4 7.3 6.9 0.1 2.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) RhoGAP PF00620.27 CAM39864.1 - 0.54 10.1 3.2 1.8 8.4 3.2 2.2 1 1 0 1 1 1 0 RhoGAP domain Syntaxin_2 PF14523.6 CAM39864.1 - 1.1 9.7 13.1 0.32 11.4 1.6 2.7 3 0 0 3 3 3 0 Syntaxin-like protein Jnk-SapK_ap_N PF09744.9 CAM39864.1 - 3.6 7.8 13.8 0.61 10.3 5.0 2.6 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 MutS_III PF05192.18 CAM39864.1 - 7.7 6.7 12.4 45 4.2 12.2 2.0 1 1 0 1 1 1 0 MutS domain III Sen15 PF09631.10 CAM39865.1 - 0.063 13.6 0.0 0.074 13.4 0.0 1.2 1 0 0 1 1 1 0 Sen15 protein Ras PF00071.22 CAM39866.1 - 2.8e-34 118.1 0.2 3.3e-34 117.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAM39866.1 - 1.8e-18 66.9 0.0 2.5e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAM39866.1 - 1.7e-10 40.6 0.0 2.2e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CAM39866.1 - 1.5e-06 27.7 0.1 2e-06 27.3 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CAM39866.1 - 5.6e-05 22.8 0.2 0.00019 21.0 0.2 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CAM39866.1 - 0.0032 17.5 0.0 0.0053 16.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 CAM39866.1 - 0.0041 16.9 0.0 0.085 12.6 0.0 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 CAM39866.1 - 0.026 13.7 0.0 0.26 10.4 0.0 2.2 2 1 1 3 3 3 0 G-protein alpha subunit WD40 PF00400.32 CAM39867.1 - 0.00029 21.6 1.1 26 5.9 0.0 5.4 5 0 0 5 5 5 1 WD domain, G-beta repeat tify PF06200.14 CAM39867.1 - 0.27 10.6 0.8 3.6 7.0 0.1 2.6 3 0 0 3 3 3 0 tify domain DHR-2 PF06920.13 CAM39868.2 - 3e-19 69.1 5.0 2.2e-16 59.6 0.1 2.6 3 0 0 3 3 3 2 Dock homology region 2 DOCK-C2 PF14429.6 CAM39868.2 - 5.4e-18 65.5 0.0 1.1e-17 64.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DUF2345 PF10106.9 CAM39868.2 - 2e-14 53.7 27.5 0.23 11.3 2.2 7.9 1 1 2 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2345) RPN1_RPN2_N PF17781.1 CAM39869.1 - 1.7e-75 254.3 0.1 3.6e-75 253.3 0.1 1.5 2 0 0 2 2 2 1 RPN1/RPN2 N-terminal domain PC_rep PF01851.22 CAM39869.1 - 5.1e-22 77.1 15.0 1.8e-05 24.9 0.0 8.7 9 0 0 9 9 9 4 Proteasome/cyclosome repeat RPN1_C PF18051.1 CAM39869.1 - 2.3e-19 69.2 0.0 4.2e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal HEAT_2 PF13646.6 CAM39869.1 - 0.0031 17.9 3.3 1.2 9.5 0.1 4.7 4 2 1 5 5 5 1 HEAT repeats IFRD PF05004.13 CAM39869.1 - 0.0095 15.1 0.4 0.035 13.2 0.1 2.2 2 0 0 2 2 2 1 Interferon-related developmental regulator (IFRD) CHASE6_C PF17150.4 CAM39869.1 - 0.054 14.2 0.0 4 8.2 0.0 2.9 1 1 1 2 2 2 0 C-terminal domain of two-partite extracellular sensor domain PhrC_PhrF PF11131.8 CAM39869.1 - 0.11 12.1 0.1 0.4 10.3 0.1 2.0 1 0 0 1 1 1 0 Rap-phr extracellular signalling IQ PF00612.27 CAM39870.2 - 0.026 14.3 10.8 0.077 12.8 2.4 2.9 2 0 0 2 2 2 0 IQ calmodulin-binding motif PreAtp-grasp PF18604.1 CAM39870.2 - 0.081 12.6 0.4 0.22 11.2 0.4 1.6 1 0 0 1 1 1 0 Pre ATP-grasp domain RNA_pol_A_bac PF01000.26 CAM39871.1 - 1e-19 70.9 0.0 1.8e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CAM39871.1 - 3.5e-16 58.4 0.0 5.3e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_9 PF13187.6 CAM39871.1 - 0.079 13.1 0.9 0.079 13.1 0.9 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain TPR_19 PF14559.6 CAM39872.2 - 4e-13 49.7 11.3 0.00076 19.9 0.1 5.6 5 1 0 6 6 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 CAM39872.2 - 3.2e-11 42.5 18.2 0.00018 21.4 0.0 8.8 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 CAM39872.2 - 1.8e-10 40.9 13.8 0.0042 17.4 0.9 6.7 5 2 1 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CAM39872.2 - 2.7e-10 40.3 11.8 1.7e-07 31.3 3.7 3.8 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 CAM39872.2 - 7.9e-09 35.0 11.7 0.038 13.8 0.0 7.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 CAM39872.2 - 3.1e-05 24.5 4.7 0.0027 18.3 0.1 4.6 4 2 1 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 CAM39872.2 - 4.3e-05 23.4 7.2 0.43 10.9 0.1 6.5 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 CAM39872.2 - 4.3e-05 24.0 13.9 0.033 15.0 0.0 6.8 7 2 2 9 9 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 CAM39872.2 - 5.9e-05 22.8 8.3 1.4 9.1 0.1 6.8 7 0 0 7 7 6 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 CAM39872.2 - 0.00025 20.7 0.7 0.03 14.0 0.0 3.7 2 1 1 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_3 PF07720.12 CAM39872.2 - 0.0085 16.1 0.2 0.0085 16.1 0.2 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat PPR PF01535.20 CAM39872.2 - 0.0092 16.2 6.9 17 6.0 0.0 4.9 5 0 0 5 5 4 0 PPR repeat SRP_TPR_like PF17004.5 CAM39872.2 - 0.0095 15.9 14.7 0.46 10.5 3.2 4.0 3 1 2 5 5 5 3 Putative TPR-like repeat TPR_6 PF13174.6 CAM39872.2 - 0.012 16.2 20.5 0.019 15.6 0.0 6.7 9 0 0 9 9 6 0 Tetratricopeptide repeat Sec16_C PF12931.7 CAM39872.2 - 0.056 13.1 1.4 0.93 9.1 0.4 2.5 2 0 0 2 2 2 0 Sec23-binding domain of Sec16 NARP1 PF12569.8 CAM39872.2 - 0.06 12.2 7.8 0.7 8.7 0.0 3.0 3 0 0 3 3 3 0 NMDA receptor-regulated protein 1 TPR_20 PF14561.6 CAM39872.2 - 0.12 12.7 3.3 28 5.2 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF1664 PF07889.12 CAM39872.2 - 0.14 12.2 0.3 5.1 7.2 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3829 PF12889.7 CAM39872.2 - 0.39 10.1 4.4 1.3 8.4 0.4 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3829) TPR_17 PF13431.6 CAM39872.2 - 1.3 9.5 4.3 1.3e+02 3.3 0.2 4.8 5 0 0 5 5 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CAM39872.2 - 4.2 7.5 17.0 10 6.3 0.3 4.9 3 1 2 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat IPP-2 PF04979.14 CAM39874.1 - 6.6e-21 75.4 4.5 7.9e-21 75.2 4.5 1.1 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) zf-RanBP PF00641.18 CAM39875.2 - 0.0083 15.4 7.1 0.0083 15.4 7.1 1.7 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 CAM39875.2 - 0.068 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4658 PF15555.6 CAM39875.2 - 0.077 13.1 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) Med9 PF07544.13 CAM39875.2 - 0.16 12.0 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 F-box_5 PF18511.1 CAM39876.1 - 0.15 11.6 0.2 0.81 9.3 0.0 2.2 2 0 0 2 2 2 0 F-box P19Arf_N PF07392.12 CAM39876.1 - 6.5 7.3 9.4 5.5 7.5 6.3 2.6 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus SNF2_N PF00176.23 CAM39877.1 - 1.4e-30 106.2 0.1 2.5e-30 105.4 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CAM39877.1 - 6.2e-11 42.6 0.3 1.4e-10 41.5 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAM39877.1 - 6.9e-07 29.4 0.0 0.0067 16.4 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 CAM39877.1 - 0.00019 21.1 0.2 0.0024 17.6 0.0 2.2 2 0 0 2 2 2 1 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 CAM39877.1 - 0.00034 19.9 0.0 0.00067 19.0 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 CAM39877.1 - 0.012 15.8 0.1 0.055 13.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain TruB_C_2 PF16198.5 CAM39877.1 - 0.018 15.2 0.9 0.078 13.1 0.9 2.2 1 0 0 1 1 1 0 tRNA pseudouridylate synthase B C-terminal domain Remorin_C PF03763.13 CAM39878.1 - 0.0016 18.3 0.7 0.0036 17.2 0.7 1.6 1 0 0 1 1 1 1 Remorin, C-terminal region DUF2207 PF09972.9 CAM39878.1 - 0.0034 16.2 0.5 0.0076 15.1 0.5 1.6 1 1 0 1 1 1 1 Predicted membrane protein (DUF2207) DctQ PF04290.12 CAM39878.1 - 0.96 9.4 8.4 6.7 6.6 7.5 2.1 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Sec23_trunk PF04811.15 CAM39879.1 - 5.9e-43 147.2 0.0 9.8e-43 146.5 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 CAM39879.1 - 2.1e-20 73.3 0.0 5.4e-20 71.9 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 CAM39879.1 - 1.2e-12 47.7 2.3 1.2e-12 47.7 2.3 1.9 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.15 CAM39879.1 - 4.4e-10 39.3 0.0 1e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 CAM39879.1 - 0.15 11.9 0.0 0.42 10.6 0.0 1.7 1 0 0 1 1 1 0 Gelsolin repeat DUF4893 PF16233.5 CAM39879.1 - 0.16 11.5 0.0 0.36 10.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4893) RasGEF_N_2 PF14663.6 CAM39880.1 - 0.16 12.4 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain RIO1 PF01163.22 CAM39881.1 - 2.7e-65 219.5 0.5 4.6e-65 218.8 0.0 1.6 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 CAM39881.1 - 0.084 12.8 0.2 0.52 10.2 0.2 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CAM39881.1 - 0.11 11.2 0.1 0.11 11.2 0.1 1.7 2 0 0 2 2 2 0 Fungal protein kinase CDC45 PF02724.14 CAM39881.1 - 0.74 8.0 12.8 1 7.6 12.8 1.2 1 0 0 1 1 1 0 CDC45-like protein STI1 PF17830.1 CAM39882.1 - 1.1e-11 44.4 15.2 1.3e-11 44.2 13.3 2.1 2 0 0 2 2 2 1 STI1 domain TPR_9 PF13371.6 CAM39882.1 - 1.9e-05 24.7 1.8 5.2e-05 23.3 0.2 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CAM39882.1 - 0.001 18.8 0.2 2.6 8.0 0.3 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 CAM39882.1 - 0.0015 18.7 0.4 0.3 11.6 0.2 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 CAM39882.1 - 0.0045 17.0 16.2 0.2 11.8 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 CAM39882.1 - 0.012 15.3 0.1 0.21 11.3 0.0 2.7 2 1 1 3 3 3 0 TPR repeat HTH_IclR PF09339.10 CAM39882.1 - 0.036 13.9 0.1 0.12 12.2 0.1 1.9 1 0 0 1 1 1 0 IclR helix-turn-helix domain DUF2999 PF11212.8 CAM39882.1 - 0.36 11.1 4.7 20 5.5 4.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2999) TPR_14 PF13428.6 CAM39882.1 - 0.5 11.3 0.2 0.5 11.3 0.2 4.1 3 1 0 4 4 4 0 Tetratricopeptide repeat P_C10 PF14974.6 CAM39882.1 - 2.5 8.2 5.3 0.61 10.2 1.1 2.1 2 0 0 2 2 2 0 Protein C10 ArfGap PF01412.18 CAM39883.1 - 1.2e-37 128.5 1.2 1.4e-37 128.3 0.0 1.7 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf OrfB_Zn_ribbon PF07282.11 CAM39883.1 - 0.059 13.3 1.4 0.14 12.1 1.4 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain KIAA1328 PF15369.6 CAM39883.1 - 0.16 11.8 6.3 0.56 10.0 3.7 2.1 2 0 0 2 2 2 0 Uncharacterised protein KIAA1328 UBA_4 PF14555.6 CAM39884.1 - 1.5e-06 27.9 0.1 3.1e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.6 CAM39884.1 - 0.00058 20.0 0.1 0.0018 18.4 0.1 1.9 2 0 0 2 2 2 1 Thioredoxin-like IQ PF00612.27 CAM39885.1 - 0.073 12.9 8.4 0.77 9.7 3.8 3.2 2 0 0 2 2 2 0 IQ calmodulin-binding motif Glycohydro_20b2 PF14845.6 CAM39885.1 - 0.084 13.5 0.6 0.41 11.3 0.0 2.4 3 1 0 3 3 3 0 beta-acetyl hexosaminidase like DUF4549 PF15082.6 CAM39885.1 - 2.4 7.9 7.9 1.3 8.8 0.2 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4549) zf-met PF12874.7 CAM39886.1 - 0.0019 18.5 0.4 0.0036 17.6 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Pkinase PF00069.25 CAM39887.1 - 3.7e-41 141.3 0.0 2.1e-19 70.0 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CAM39887.1 - 1.7e-21 76.7 0.0 8.8e-13 48.1 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 CAM39887.1 - 0.011 15.1 0.0 4.4 6.5 0.0 2.4 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 CAM39887.1 - 0.035 14.0 1.0 0.15 11.9 0.3 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 CAM39887.1 - 0.044 12.7 0.0 0.067 12.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase C2-C2_1 PF11618.8 CAM39888.2 - 4.3e-07 30.1 5.1 3.1e-06 27.3 0.0 3.8 4 0 0 4 4 4 1 First C2 domain of RPGR-interacting protein 1 Fez1 PF06818.15 CAM39888.2 - 1.6 9.1 47.5 1.2 9.5 19.9 4.4 4 1 0 4 4 4 0 Fez1 TraG_N PF07916.11 CAM39888.2 - 3.6 6.3 15.0 1.6 7.5 4.8 2.5 2 0 0 2 2 2 0 TraG-like protein, N-terminal region COMM_domain PF07258.14 CAM39888.2 - 7.8 6.7 7.8 1.8 8.7 0.1 3.6 4 0 0 4 4 4 0 COMM domain RRM_1 PF00076.22 CAM39889.1 - 5.7e-15 54.9 0.1 1.3e-06 28.1 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CAM39889.1 - 0.045 13.8 0.1 2.4 8.2 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RNA_pol_Rpb4 PF03874.16 CAM39890.1 - 4.7e-05 23.7 0.0 6e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb4 Prolamin_like PF05617.11 CAM39890.1 - 0.047 13.9 0.0 0.069 13.3 0.0 1.3 1 0 0 1 1 1 0 Prolamin-like zf-CCCH PF00642.24 CAM39892.1 - 0.0083 16.0 0.4 0.012 15.5 0.4 1.2 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CAM39892.1 - 0.02 15.6 0.0 0.039 14.7 0.0 1.4 1 0 0 1 1 1 0 Torus domain zf_CCCH_4 PF18345.1 CAM39892.1 - 1.1 9.4 5.7 1.7 8.8 5.7 1.3 1 0 0 1 1 1 0 Zinc finger domain PPR_1 PF12854.7 CAM39893.1 - 0.03 14.0 0.1 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 PPR repeat PPR PF01535.20 CAM39893.1 - 0.03 14.6 0.0 24 5.4 0.0 3.7 3 0 0 3 3 3 0 PPR repeat PPR_2 PF13041.6 CAM39893.1 - 0.12 12.6 0.0 0.5 10.6 0.0 2.1 1 0 0 1 1 1 0 PPR repeat family HycH PF07450.11 CAM39893.1 - 0.12 12.7 0.0 1.7 9.0 0.0 2.5 2 0 0 2 2 2 0 Formate hydrogenlyase maturation protein HycH DUF2890 PF11081.8 CAM39893.1 - 0.25 11.5 1.6 0.48 10.5 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Metallophos PF00149.28 CAM39894.1 - 4e-06 27.5 0.0 5.7e-06 27.0 0.0 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Arginase PF00491.21 CAM39894.1 - 0.11 11.9 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Arginase family Rad51 PF08423.11 CAM39895.1 - 5.2e-18 65.2 0.3 1.9e-08 33.9 0.1 2.1 2 0 0 2 2 2 2 Rad51 RecA PF00154.21 CAM39895.1 - 3e-07 30.2 0.6 3.2e-06 26.8 0.0 2.2 2 0 0 2 2 2 1 recA bacterial DNA recombination protein ATPase PF06745.13 CAM39895.1 - 4.1e-06 26.3 0.0 7.3e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 KaiC DUF2075 PF09848.9 CAM39895.1 - 0.27 10.4 0.0 0.43 9.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Phage_GP20 PF06810.11 CAM39896.1 - 0.1 12.4 12.5 0.025 14.4 4.1 2.6 2 0 0 2 2 2 0 Phage minor structural protein GP20 Gly-zipper_Omp PF13488.6 CAM39897.1 - 0.03 14.3 12.8 0.031 14.3 8.2 2.6 2 0 0 2 2 2 0 Glycine zipper Peptidase_M26_C PF07580.14 CAM39899.1 - 0.11 10.9 0.1 0.15 10.6 0.1 1.1 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase C-terminal region CaATP_NAI PF12515.8 CAM39900.1 - 3.4e-17 61.8 0.0 1.1e-16 60.2 0.0 2.0 1 0 0 1 1 1 1 Ca2+-ATPase N terminal autoinhibitory domain F-box-like PF12937.7 CAM39900.1 - 0.082 12.8 1.0 0.49 10.3 0.3 2.7 2 1 0 2 2 2 0 F-box-like Cofilin_ADF PF00241.20 CAM39901.1 - 3.9e-30 104.1 0.0 4.5e-30 104.0 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein RNase_T PF00929.24 CAM39904.1 - 5.9e-25 88.7 0.0 2.1e-23 83.6 0.0 2.1 1 1 0 1 1 1 1 Exonuclease RNase_T PF00929.24 CAM39905.2 - 5e-26 92.2 0.0 8e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 CAM39905.2 - 0.15 12.0 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 3' exoribonuclease, RNase T-like FHA PF00498.26 CAM39906.1 - 1.3e-06 28.7 0.0 1.5e-05 25.2 0.0 2.2 1 1 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CAM39906.1 - 0.0054 17.0 0.0 2.8 8.3 0.0 2.3 2 0 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain DIOX_N PF14226.6 CAM39907.1 - 5e-35 120.8 0.0 8e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CAM39907.1 - 6.2e-25 87.6 0.0 1.2e-24 86.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2914 PF11141.8 CAM39907.1 - 0.11 12.2 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) TTL PF03133.15 CAM39908.1 - 2.5e-41 141.7 0.0 1.6e-17 63.6 0.0 3.2 3 0 0 3 3 3 3 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 CAM39908.1 - 0.002 17.5 0.0 1 8.5 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp zf-C2HC_2 PF13913.6 CAM39911.1 - 9.2e-17 60.5 8.0 1.4e-09 37.6 1.4 2.3 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-Di19 PF05605.12 CAM39911.1 - 0.00017 21.8 2.4 0.047 14.0 0.5 2.5 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 CAM39911.1 - 0.00027 21.5 5.7 0.095 13.6 1.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-RING_7 PF02591.15 CAM39911.1 - 0.018 15.2 3.9 1.8 8.8 0.1 2.8 3 0 0 3 3 2 0 C4-type zinc ribbon domain Nairovirus_M PF07948.11 CAM39911.1 - 0.029 12.6 2.5 0.54 8.4 0.3 2.1 2 0 0 2 2 2 0 Nairovirus M polyprotein-like Zn-ribbon_8 PF09723.10 CAM39911.1 - 0.038 14.1 5.6 0.8 9.9 0.2 2.8 2 1 1 3 3 3 0 Zinc ribbon domain zf_UBZ PF18439.1 CAM39911.1 - 0.051 13.2 1.1 4.7 6.9 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-ribbon_3 PF13248.6 CAM39911.1 - 0.055 12.9 3.8 2.2 7.8 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2 PF00096.26 CAM39911.1 - 0.072 13.6 5.8 2 9.0 2.1 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Lar_restr_allev PF14354.6 CAM39911.1 - 0.085 13.3 4.7 0.44 11.0 0.4 2.6 2 0 0 2 2 2 0 Restriction alleviation protein Lar zf-FPG_IleRS PF06827.14 CAM39911.1 - 0.16 11.9 10.0 1.1 9.2 2.4 2.6 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-CHCC PF10276.9 CAM39911.1 - 0.18 11.9 1.5 9.8 6.3 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger domain zf-C2H2_11 PF16622.5 CAM39911.1 - 0.19 11.5 2.4 14 5.5 0.2 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zinc_ribbon_9 PF14369.6 CAM39911.1 - 0.19 12.0 7.8 3.9 7.8 0.3 3.4 4 0 0 4 4 3 0 zinc-ribbon TRAF6_Z2 PF18048.1 CAM39911.1 - 0.22 11.7 1.2 12 6.1 0.4 2.4 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 zf-H2C2_2 PF13465.6 CAM39911.1 - 0.26 11.8 1.1 26 5.4 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger double domain Sgf11 PF08209.11 CAM39911.1 - 0.28 10.8 3.2 1.9 8.1 0.2 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Zn_Tnp_IS1595 PF12760.7 CAM39911.1 - 0.44 10.6 3.5 9.3 6.3 1.1 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF2256 PF10013.9 CAM39911.1 - 0.74 10.0 6.2 3.2 7.9 0.1 3.0 3 0 0 3 3 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc_ribbon_2 PF13240.6 CAM39911.1 - 2.3 8.1 8.3 4.8 7.0 0.0 2.7 3 0 0 3 3 2 0 zinc-ribbon domain YacG PF03884.14 CAM39911.1 - 3.7 7.3 6.8 2.1 8.1 1.4 2.4 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG Prim_Zn_Ribbon PF08273.12 CAM39911.1 - 6.3 7.2 8.0 7 7.0 0.5 2.8 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Piwi PF02171.17 CAM39912.1 - 1.1e-06 28.1 0.0 1.7e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Piwi domain MecA_N PF05223.11 CAM39912.1 - 0.1 12.8 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 NTF2-like N-terminal transpeptidase domain RNase_T PF00929.24 CAM39913.1 - 9.2e-28 97.9 0.0 1.4e-27 97.2 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Ank_2 PF12796.7 CAM39914.2 - 1.2e-13 51.5 5.3 4.1e-07 30.5 0.4 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CAM39914.2 - 5.1e-08 33.3 0.6 0.0035 17.9 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 CAM39914.2 - 2.6e-06 27.6 1.7 0.13 12.8 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 CAM39914.2 - 9.5e-06 25.6 1.2 3.6 8.5 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 CAM39914.2 - 0.014 15.7 2.3 0.72 10.3 0.2 3.0 2 1 0 2 2 2 0 Ankyrin repeats (many copies) ERCC3_RAD25_C PF16203.5 CAM39916.2 - 2.5e-61 207.0 0.0 9.4e-54 182.2 0.0 2.2 2 0 0 2 2 2 2 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 CAM39916.2 - 4.2e-14 52.9 0.0 6.4e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CAM39916.2 - 5.4e-10 39.6 0.0 1.4e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_3 PF13625.6 CAM39916.2 - 1.8e-08 34.6 0.1 6.2e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CAM39916.2 - 0.022 14.5 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase zf-NF-X1 PF01422.17 CAM39917.1 - 2.5e-07 30.6 59.8 3e-05 24.0 18.5 14.3 13 0 0 13 13 13 6 NF-X1 type zinc finger ABC2_membrane_3 PF12698.7 CAM39919.1 - 2.8e-60 204.3 54.0 4.5e-44 151.0 23.3 3.0 3 0 0 3 3 3 2 ABC-2 family transporter protein ABC_tran PF00005.27 CAM39919.1 - 3.5e-57 192.8 0.0 3e-27 95.8 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CAM39919.1 - 4.2e-10 39.9 5.3 0.011 15.6 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CAM39919.1 - 8.4e-09 35.2 1.3 0.00027 20.4 0.0 3.6 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CAM39919.1 - 3.7e-05 23.4 1.8 0.0057 16.4 0.2 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 CAM39919.1 - 0.0011 18.7 0.3 0.15 11.7 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 CAM39919.1 - 0.0018 18.8 0.7 0.21 12.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CAM39919.1 - 0.0018 18.2 1.1 0.95 9.3 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase DUF3694 PF12473.8 CAM39919.1 - 0.026 15.2 0.2 3.9 8.1 0.1 2.5 2 0 0 2 2 2 0 Kinesin protein Arf PF00025.21 CAM39919.1 - 0.048 13.1 0.0 0.4 10.1 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_25 PF13481.6 CAM39919.1 - 0.083 12.5 0.9 12 5.4 0.1 2.8 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 CAM39919.1 - 0.12 12.6 0.1 6.4 7.1 0.1 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_27 PF13514.6 CAM39919.1 - 0.25 10.9 0.3 1.1 8.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 CAM39919.1 - 0.4 10.3 2.6 2.8 7.5 0.3 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ERM PF00769.19 CAM39920.1 - 0.031 14.1 0.5 0.041 13.7 0.5 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF2207 PF09972.9 CAM39920.1 - 0.092 11.5 0.0 0.1 11.3 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DcpS_C PF11969.8 CAM39921.2 - 2.6e-23 82.7 1.0 4.4e-23 81.9 0.6 1.5 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 CAM39921.2 - 5.2e-13 49.6 0.1 1.5e-12 48.1 0.1 1.8 2 0 0 2 2 2 1 HIT domain zf-C2HE PF16278.5 CAM39921.2 - 4.3e-09 36.7 0.0 8.3e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger PHO4 PF01384.20 CAM39922.1 - 9.5e-83 278.0 18.2 1.2e-82 277.7 18.2 1.1 1 0 0 1 1 1 1 Phosphate transporter family DUF436 PF04260.12 CAM39922.1 - 0.056 13.0 0.3 0.14 11.7 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF436) Radial_spoke PF04712.12 CAM39923.2 - 5.5e-119 398.3 0.0 8.6e-119 397.7 0.0 1.2 1 0 0 1 1 1 1 Radial spokehead-like protein RRM_1 PF00076.22 CAM39925.1 - 4.7e-23 80.8 0.0 2e-14 53.2 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CAM39925.1 - 0.0024 17.7 0.0 2.5 8.0 0.0 3.1 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 CAM39925.1 - 0.18 12.0 0.0 16 5.7 0.0 2.7 2 1 0 2 2 2 0 RNA recognition motif RHD3 PF05879.12 CAM39926.1 - 0.0044 15.2 0.0 0.0058 14.8 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) CLAMP PF14769.6 CAM39927.1 - 0.001 19.5 0.0 0.029 14.8 0.0 2.6 2 0 0 2 2 2 1 Flagellar C1a complex subunit C1a-32 BBS2_Mid PF14783.6 CAM39928.1 - 0.0016 18.5 0.1 1.9 8.6 0.0 2.8 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region FG-GAP PF01839.23 CAM39928.1 - 0.0043 17.1 2.7 0.0043 17.1 2.7 1.9 2 0 0 2 2 2 1 FG-GAP repeat VCBS PF13517.6 CAM39928.1 - 0.014 15.9 0.2 0.053 14.1 0.0 2.1 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella BBS2_C PF14782.6 CAM39928.1 - 0.072 11.9 0.8 5.7 5.6 0.0 2.8 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, C-terminal EF_TS PF00889.19 CAM39929.1 - 2.1e-13 50.4 0.0 5.3e-13 49.0 0.0 1.7 1 1 1 2 2 2 1 Elongation factor TS WD40 PF00400.32 CAM39932.1 - 5e-17 62.0 9.7 0.00045 21.0 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Neocarzinostat PF00960.18 CAM39932.1 - 0.072 13.1 0.5 0.14 12.1 0.5 1.5 1 0 0 1 1 1 0 Neocarzinostatin family Mpp10 PF04006.12 CAM39933.1 - 9.8e-64 215.9 34.5 1.8e-63 215.0 34.5 1.5 1 1 0 1 1 1 1 Mpp10 protein HSP90 PF00183.18 CAM39934.1 - 6.6e-172 573.0 6.3 8.7e-172 572.6 6.3 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.6 CAM39934.1 - 1.4e-07 31.4 0.0 3.8e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CAM39934.1 - 3.2e-07 30.8 0.0 1e-06 29.2 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GSH-S_ATP PF02955.16 CAM39934.1 - 0.033 13.6 0.0 1.5 8.2 0.0 2.4 2 0 0 2 2 2 0 Prokaryotic glutathione synthetase, ATP-grasp domain Coilin_N PF15862.5 CAM39934.1 - 0.077 12.8 0.1 0.92 9.3 0.0 2.6 3 0 0 3 3 3 0 Coilin N-terminus Plasmid_RAQPRD PF09686.10 CAM39935.1 - 0.057 13.6 5.2 2.1 8.6 0.3 2.4 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) U-box PF04564.15 CAM39936.1 - 3.9e-12 46.2 0.0 4.5e-11 42.8 0.0 2.7 3 0 0 3 3 3 1 U-box domain zf-Nse PF11789.8 CAM39936.1 - 0.00026 20.8 0.0 0.00072 19.3 0.0 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit YjbT PF17089.5 CAM39936.1 - 0.02 14.9 0.2 1.6 8.8 0.0 2.9 2 0 0 2 2 2 0 Uncharacterised protein family zf-NOSIP PF15906.5 CAM39936.1 - 0.083 13.0 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Peptidase_C1 PF00112.23 CAM39941.1 - 4.7e-61 206.7 4.0 5.6e-61 206.4 4.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CAM39941.1 - 1.9e-05 23.6 0.6 0.0016 17.3 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Propeptide_C1 PF08127.13 CAM39941.1 - 0.0059 16.5 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 Peptidase family C1 propeptide RecO_N_2 PF13114.6 CAM39941.1 - 0.095 12.4 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 RecO N terminal DUF998 PF06197.13 CAM39942.1 - 0.05 13.2 0.2 0.084 12.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF998) Nop14 PF04147.12 CAM39942.1 - 1.8 6.6 5.3 2.3 6.3 5.3 1.1 1 0 0 1 1 1 0 Nop14-like family FoP_duplication PF13865.6 CAM39942.1 - 2 9.0 10.8 4.2 8.0 10.8 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 DUF1634 PF07843.11 CAM39943.1 - 0.36 10.9 4.6 4.1 7.5 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1634) HMG_box PF00505.19 CAM39944.1 - 2.5e-30 104.7 18.0 1.6e-20 73.2 1.1 3.1 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 CAM39944.1 - 4.5e-20 72.0 19.8 2.8e-12 47.1 1.2 3.1 2 1 1 3 3 3 2 HMG-box domain Protamine_like PF06382.11 CAM39944.1 - 4.8e-08 33.3 13.6 0.00011 22.4 1.9 2.2 1 1 1 2 2 2 2 Protamine and protamine like DEK_C PF08766.11 CAM39944.1 - 5.9e-06 26.1 0.0 1.2e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 DEK C terminal domain HMG_box_5 PF14887.6 CAM39944.1 - 0.0061 16.5 15.7 0.014 15.3 0.9 2.9 3 0 0 3 3 3 2 HMG (high mobility group) box 5 COX4 PF02936.14 CAM39944.1 - 0.0062 16.6 3.6 0.76 9.8 0.5 2.5 2 0 0 2 2 2 2 Cytochrome c oxidase subunit IV YABBY PF04690.13 CAM39944.1 - 0.012 16.2 4.2 0.012 16.2 4.2 1.8 1 1 2 3 3 3 0 YABBY protein DUF2582 PF10771.9 CAM39944.1 - 0.057 13.6 0.9 2.2 8.5 0.1 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix domain (DUF2582) Mon1 PF03164.14 CAM39944.1 - 0.084 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Trafficking protein Mon1 DUF538 PF04398.12 CAM39944.1 - 0.11 12.9 0.0 0.72 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF538 DUF755 PF05501.11 CAM39944.1 - 6.7 7.0 21.6 2.8 8.3 5.9 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF755) RRM_1 PF00076.22 CAM39946.1 - 5.4e-07 29.3 0.0 8.6e-07 28.7 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CAM39946.1 - 0.028 14.0 0.0 0.032 13.8 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CAM39946.1 - 0.068 13.0 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif Amidohydro_1 PF01979.20 CAM39947.1 - 3.8e-56 190.9 0.0 6.5e-56 190.1 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CAM39947.1 - 3.3e-10 40.0 0.0 2e-06 27.6 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Cyt-b5 PF00173.28 CAM39948.1 - 8.4e-09 35.5 0.0 1.3e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4932 PF16286.5 CAM39949.1 - 0.053 12.8 0.0 0.093 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4932) TPR_19 PF14559.6 CAM39949.1 - 0.81 10.2 4.2 7.1 7.2 0.0 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat Arf PF00025.21 CAM39950.1 - 5.9e-64 214.7 0.0 6.6e-64 214.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CAM39950.1 - 1.4e-14 54.4 0.0 1.9e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CAM39950.1 - 1.5e-14 53.9 0.0 1.8e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CAM39950.1 - 1.9e-14 53.6 0.0 2.2e-14 53.4 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CAM39950.1 - 3.8e-12 46.1 0.0 4.8e-09 35.8 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CAM39950.1 - 1.1e-10 41.2 0.0 1.4e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CAM39950.1 - 2.7e-08 33.9 0.0 3.9e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase TniB PF05621.11 CAM39950.1 - 0.0049 16.3 0.0 0.0081 15.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein cobW PF02492.19 CAM39950.1 - 0.0074 15.9 0.0 0.11 12.1 0.0 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 CAM39950.1 - 0.059 13.3 0.0 11 5.9 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 CAM39950.1 - 0.12 12.7 0.1 0.24 11.8 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain C1_1 PF00130.22 CAM39951.1 - 0.0003 20.6 7.2 0.0003 20.6 7.2 2.0 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 CAM39951.1 - 0.00047 20.0 9.4 0.00091 19.1 9.4 1.5 1 0 0 1 1 1 1 PHD-finger PhyH PF05721.13 CAM39951.1 - 0.0013 19.0 0.0 0.0041 17.4 0.0 2.1 2 1 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) Prok-RING_1 PF14446.6 CAM39951.1 - 0.2 11.6 9.9 0.52 10.3 9.9 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_4 PF16866.5 CAM39951.1 - 0.28 11.3 7.8 0.65 10.1 7.8 1.6 1 0 0 1 1 1 0 PHD-finger OrfB_Zn_ribbon PF07282.11 CAM39951.1 - 5.5 7.0 8.8 0.41 10.6 3.3 1.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DZR PF12773.7 CAM39951.1 - 6 7.0 8.8 23 5.1 8.8 2.0 1 1 0 1 1 1 0 Double zinc ribbon SLC35F PF06027.12 CAM39952.1 - 5e-63 213.4 28.2 5.5e-47 160.7 7.9 2.0 2 0 0 2 2 2 2 Solute carrier family 35 CRT-like PF08627.10 CAM39952.1 - 2.6e-13 49.6 7.3 2.6e-13 49.6 7.3 1.9 2 1 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 CAM39952.1 - 9.8e-10 38.7 42.6 0.00016 21.9 13.7 3.2 3 0 0 3 3 3 3 EamA-like transporter family IPPT PF01715.17 CAM39953.1 - 2.5e-15 56.9 0.0 4.2e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 IPP transferase zf-met PF12874.7 CAM39953.1 - 4e-07 30.2 0.3 7.4e-07 29.4 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF3449 PF11931.8 CAM39953.1 - 0.015 15.1 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) AKAP95 PF04988.12 CAM39953.1 - 0.019 15.2 0.1 0.035 14.4 0.1 1.3 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_jaz PF12171.8 CAM39953.1 - 0.034 14.4 0.1 0.066 13.5 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Peptidase_A22B PF04258.13 CAM39954.1 - 3.1e-60 204.1 18.1 6.2e-55 186.7 11.3 2.0 1 1 1 2 2 2 2 Signal peptide peptidase DUF2157 PF09925.9 CAM39954.1 - 0.97 9.2 6.2 3.4 7.5 6.2 2.1 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) LETM1 PF07766.13 CAM39955.1 - 2.3e-61 207.5 0.0 1.1e-60 205.3 0.0 1.9 2 0 0 2 2 2 1 LETM1-like protein DASH_Duo1 PF08651.10 CAM39955.1 - 0.061 13.1 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 DASH complex subunit Duo1 ABC_tran PF00005.27 CAM39956.1 - 0.0015 19.0 0.0 0.0025 18.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter FGE-sulfatase PF03781.16 CAM39958.1 - 5.2e-20 72.1 0.3 1.1e-19 71.0 0.3 1.6 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Methyltransf_25 PF13649.6 CAM39958.1 - 1.5e-06 28.8 0.2 0.00019 22.1 0.2 2.6 1 1 0 1 1 1 1 Methyltransferase domain DinB_2 PF12867.7 CAM39958.1 - 1.8e-06 28.5 0.0 4.5e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 DinB superfamily Methyltransf_31 PF13847.6 CAM39958.1 - 0.0006 19.6 0.0 0.014 15.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAM39958.1 - 0.0032 17.3 0.1 0.0094 15.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAM39958.1 - 0.0038 17.9 0.1 0.028 15.1 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAM39958.1 - 0.012 16.3 0.0 0.034 14.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain DUF2938 PF11158.8 CAM39959.1 - 0.047 13.2 0.0 0.08 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2938) DUF2206 PF09971.9 CAM39959.1 - 0.29 9.9 0.9 0.41 9.4 0.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) Kinesin PF00225.23 CAM39961.1 - 1.4e-83 280.6 0.0 1.4e-83 280.6 0.0 3.0 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CAM39961.1 - 2.6e-15 56.7 0.0 1.8e-14 53.9 0.0 2.6 1 0 0 1 1 1 1 Microtubule binding CCDC106 PF15794.5 CAM39964.1 - 0.00028 20.7 2.1 0.18 11.5 2.4 2.7 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 106 Baculo_PEP_C PF04513.12 CAM39964.1 - 0.00041 20.4 2.6 0.95 9.5 0.8 3.1 3 0 0 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4795 PF16043.5 CAM39964.1 - 0.0024 17.5 3.3 0.0024 17.5 3.3 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4795) YabA PF06156.13 CAM39964.1 - 0.028 15.1 1.5 0.028 15.1 1.5 4.2 4 2 1 5 5 3 0 Initiation control protein YabA Mto2_bdg PF12808.7 CAM39964.1 - 0.069 13.4 0.2 0.069 13.4 0.2 3.5 3 0 0 3 3 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Tropomyosin_1 PF12718.7 CAM39964.1 - 0.1 12.8 17.4 2.3 8.4 0.2 4.0 3 1 1 4 4 4 0 Tropomyosin like TMF_TATA_bd PF12325.8 CAM39964.1 - 0.11 12.8 14.7 0.1 12.9 1.5 3.2 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Qua1 PF16274.5 CAM39964.1 - 0.14 12.0 0.0 0.41 10.5 0.0 1.8 1 0 0 1 1 1 0 Qua1 domain SKA1 PF07160.12 CAM39964.1 - 0.19 11.6 12.7 4.2 7.1 3.3 3.3 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 DUF5446 PF17522.2 CAM39964.1 - 0.19 11.9 0.1 0.19 11.9 0.1 3.5 4 0 0 4 4 3 0 Family of unknown function (DUF5446) bZIP_1 PF00170.21 CAM39964.1 - 0.6 10.2 5.4 2.1 8.5 0.1 3.7 2 1 1 3 3 3 0 bZIP transcription factor ZapB PF06005.12 CAM39964.1 - 0.83 10.1 18.0 0.17 12.4 0.7 3.9 3 0 0 3 3 3 0 Cell division protein ZapB DUF948 PF06103.11 CAM39964.1 - 1 9.7 3.7 12 6.3 1.1 3.1 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Phage_GP20 PF06810.11 CAM39964.1 - 1.4 8.7 12.7 0.35 10.7 4.5 3.0 4 0 0 4 4 4 0 Phage minor structural protein GP20 Spc7 PF08317.11 CAM39964.1 - 1.4 7.7 21.0 0.022 13.7 5.1 3.1 3 0 0 3 3 3 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 CAM39964.1 - 2.3 7.7 18.4 0.52 9.8 4.5 3.1 2 1 1 3 3 3 0 Exonuclease VII, large subunit TSC22 PF01166.18 CAM39964.1 - 2.3 8.6 13.0 4.3 7.7 0.0 5.2 6 1 0 6 6 5 0 TSC-22/dip/bun family bZIP_2 PF07716.15 CAM39964.1 - 2.8 8.1 10.8 0.8 9.8 0.2 4.6 5 0 0 5 5 5 0 Basic region leucine zipper BLOC1_2 PF10046.9 CAM39964.1 - 2.9 8.3 8.3 0.38 11.1 0.4 3.1 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LPP PF04728.13 CAM39964.1 - 3.3 8.2 8.8 1.9 9.0 1.1 4.2 4 0 0 4 4 4 0 Lipoprotein leucine-zipper Arfaptin PF06456.13 CAM39964.1 - 3.6 7.1 12.3 0.072 12.7 1.2 2.7 3 0 0 3 3 2 0 Arfaptin-like domain Atg14 PF10186.9 CAM39964.1 - 5.2 6.0 12.5 0.45 9.6 3.0 2.9 3 0 0 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 AATF-Che1 PF13339.6 CAM39964.1 - 7.5 7.2 13.9 23 5.7 4.8 3.9 3 2 0 3 3 3 0 Apoptosis antagonizing transcription factor ADH_zinc_N_2 PF13602.6 CAM39965.2 - 6.9e-16 59.5 0.0 1.9e-15 58.1 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CAM39965.2 - 2.9e-10 40.0 3.2 6.7e-10 38.8 0.2 2.4 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CAM39965.2 - 4.3e-07 30.0 0.1 2.9e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase SseB PF07179.12 CAM39966.1 - 0.006 16.8 0.0 3 8.1 0.0 2.5 2 0 0 2 2 2 2 SseB protein N-terminal domain CorA PF01544.18 CAM39967.1 - 0.93 8.8 4.2 1.2 8.3 4.2 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein MCM3AP_GANP PF16769.5 CAM39967.1 - 1 7.5 7.3 1.2 7.4 7.3 1.2 1 0 0 1 1 1 0 MCM3AP domain of GANP cNMP_binding PF00027.29 CAM39968.2 - 8.6e-14 51.4 0.0 2.1e-07 30.9 0.0 4.9 5 0 0 5 5 5 4 Cyclic nucleotide-binding domain Ku PF02735.16 CAM39969.1 - 3e-24 85.8 0.0 6e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 CAM39969.1 - 7.3e-17 61.9 0.0 5.4e-10 39.4 0.0 2.5 3 0 0 3 3 3 2 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 CAM39969.1 - 0.00061 20.4 0.0 0.11 13.3 0.2 2.6 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm HeH PF12949.7 CAM39969.1 - 0.0061 16.3 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 HeH/LEM domain Ribosomal_L4 PF00573.22 CAM39971.1 - 2.1e-35 122.2 0.1 3.2e-35 121.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 CAM39971.1 - 7.4e-20 70.8 4.9 1.4e-19 69.9 2.4 2.3 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Ank_2 PF12796.7 CAM39972.1 - 2.8e-26 91.9 0.1 2.7e-11 43.9 0.0 4.2 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CAM39972.1 - 1e-23 83.4 0.1 3e-10 40.4 0.0 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CAM39972.1 - 1.5e-22 77.2 0.7 0.024 15.1 0.0 7.0 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 CAM39972.1 - 3.3e-18 65.5 0.6 5.5e-06 26.6 0.0 5.5 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 CAM39972.1 - 6.8e-17 61.1 0.5 0.0015 18.9 0.0 6.9 8 0 0 8 8 8 3 Ankyrin repeat B12-binding_2 PF02607.17 CAM39972.1 - 0.043 14.2 0.9 4.8 7.7 0.0 3.4 4 0 0 4 4 4 0 B12 binding domain Ribosomal_L4 PF00573.22 CAM39974.1 - 2.1e-35 122.2 0.1 3.2e-35 121.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 CAM39974.1 - 7.4e-20 70.8 4.9 1.4e-19 69.9 2.4 2.3 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain PSP1 PF04468.12 CAM39975.1 - 2.2e-17 63.1 0.1 3.5e-17 62.4 0.1 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Thioredoxin_8 PF13905.6 CAM39976.1 - 2.6e-10 40.5 0.0 4.6e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 CAM39976.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Redoxin Thioredoxin_8 PF13905.6 CAM39977.1 - 2e-20 72.9 0.0 5.8e-16 58.6 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 CAM39977.1 - 4.6e-12 45.9 0.0 8.5e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CAM39977.1 - 5.1e-12 45.7 0.0 1.7e-11 44.0 0.0 1.7 2 0 0 2 2 2 1 Redoxin Thioredoxin PF00085.20 CAM39977.1 - 2.6e-07 30.6 0.0 6.2e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin TraF PF13728.6 CAM39977.1 - 1.4e-05 25.1 0.1 3.3e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 CAM39977.1 - 0.00022 21.3 0.0 0.00049 20.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 CAM39977.1 - 0.00046 20.6 0.0 0.0023 18.4 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 CAM39977.1 - 0.018 14.8 0.0 0.041 13.7 0.0 1.5 2 0 0 2 2 2 0 Thioredoxin Hex_IIIa PF02455.16 CAM39977.1 - 0.19 10.4 0.1 0.26 10.0 0.1 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Thioredoxin_8 PF13905.6 CAM39978.1 - 4.1e-22 78.3 0.0 5.5e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 CAM39978.1 - 7.8e-07 29.0 0.0 9e-07 28.9 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CAM39978.1 - 2.7e-06 27.2 0.0 2.9e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin PF00085.20 CAM39978.1 - 3.7e-06 26.9 0.2 3.5e-05 23.7 0.1 2.0 1 1 1 2 2 2 1 Thioredoxin TraF PF13728.6 CAM39978.1 - 9.3e-05 22.3 0.0 0.00037 20.4 0.0 1.8 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 CAM39978.1 - 0.00021 21.7 0.0 0.00042 20.7 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain DUF953 PF06110.11 CAM39978.1 - 0.017 14.7 0.0 4.9 6.8 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_7 PF13899.6 CAM39978.1 - 0.031 14.5 0.0 0.05 13.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_9 PF14595.6 CAM39978.1 - 0.054 13.3 0.0 0.63 9.8 0.0 2.0 1 1 0 1 1 1 0 Thioredoxin Thioredoxin_8 PF13905.6 CAM39979.1 - 4.3e-23 81.5 0.0 6.3e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 CAM39979.1 - 6.6e-09 35.7 0.0 1.3e-08 34.8 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 CAM39979.1 - 1.9e-08 34.2 0.0 3.1e-08 33.5 0.0 1.3 1 1 0 1 1 1 1 Redoxin Thioredoxin PF00085.20 CAM39979.1 - 6.1e-08 32.6 0.0 5.9e-07 29.4 0.0 1.9 1 1 0 2 2 2 1 Thioredoxin TraF PF13728.6 CAM39979.1 - 6.7e-06 26.1 0.0 3.4e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 CAM39979.1 - 0.0043 17.5 0.0 0.0081 16.6 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 CAM39979.1 - 0.03 14.1 0.0 0.078 12.7 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.6 CAM39979.1 - 0.047 13.9 0.0 0.067 13.4 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_8 PF13905.6 CAM39980.2 - 1.7e-23 82.7 0.0 2.5e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 CAM39980.2 - 1.7e-09 37.7 0.0 2.7e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CAM39980.2 - 3.4e-09 36.6 0.0 4.5e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin PF00085.20 CAM39980.2 - 1e-07 31.9 0.0 3e-07 30.3 0.0 1.7 1 1 1 2 2 2 1 Thioredoxin TraF PF13728.6 CAM39980.2 - 2.6e-05 24.2 0.0 8.9e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 CAM39980.2 - 0.0012 19.3 0.0 0.002 18.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CAM39980.2 - 0.018 15.2 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_9 PF14595.6 CAM39980.2 - 0.059 13.1 0.0 0.1 12.4 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin Thioredoxin_4 PF13462.6 CAM39980.2 - 0.12 12.5 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin EF-hand_7 PF13499.6 CAM39981.2 - 3.3e-05 24.2 0.0 0.00012 22.4 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CAM39981.2 - 9.8e-05 21.6 0.0 0.00019 20.8 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CAM39981.2 - 0.0023 17.7 0.0 0.0055 16.6 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain G-gamma PF00631.22 CAM39981.2 - 0.055 13.5 0.1 0.35 10.9 0.0 2.1 2 0 0 2 2 2 0 GGL domain EF-hand_8 PF13833.6 CAM39981.2 - 0.094 12.6 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair SPT16 PF08644.11 CAM39981.2 - 0.11 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) Thioredoxin_8 PF13905.6 CAM39982.2 - 4.3e-06 27.0 0.0 0.26 11.7 0.0 3.3 3 0 0 3 3 3 3 Thioredoxin-like DPM3 PF08285.11 CAM39984.1 - 2.6 8.3 10.0 0.18 12.0 4.2 2.1 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF572 PF04502.13 CAM39986.1 - 3.2e-19 69.7 8.0 5.3e-19 69.0 8.0 1.4 1 1 0 1 1 1 1 Family of unknown function (DUF572) Sec16_C PF12931.7 CAM39987.2 - 7.9e-14 52.0 0.0 1.2e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 HSP70 PF00012.20 CAM39988.1 - 6.7e-26 90.6 9.1 1.4e-25 89.6 0.1 2.5 1 1 1 2 2 2 2 Hsp70 protein TPR_1 PF00515.28 CAM39988.1 - 4.4e-10 38.9 0.1 6.7e-06 25.7 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CAM39988.1 - 8.4e-10 38.0 0.4 0.0001 22.1 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CAM39988.1 - 2.6e-07 30.8 0.3 4.5e-05 23.7 0.0 3.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CAM39988.1 - 2.9e-07 30.2 0.1 0.00019 21.4 0.1 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CAM39988.1 - 1e-05 25.2 0.0 0.23 11.6 0.0 3.5 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 CAM39988.1 - 1.8e-05 24.8 1.2 0.00016 21.8 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 CAM39988.1 - 3e-05 24.5 0.2 0.0004 21.0 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CAM39988.1 - 0.00034 21.1 0.6 0.01 16.3 0.1 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CAM39988.1 - 0.00091 19.4 1.4 0.0031 17.7 0.3 2.2 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 CAM39988.1 - 0.0019 17.9 0.5 0.086 12.5 0.0 2.9 2 1 1 3 3 3 2 TPR repeat ANAPC5 PF12862.7 CAM39988.1 - 0.0051 16.8 0.9 0.2 11.7 0.1 3.4 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_17 PF13431.6 CAM39988.1 - 0.0052 17.1 0.0 0.02 15.2 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 CAM39988.1 - 0.029 15.0 0.8 0.7 10.7 0.7 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 CAM39988.1 - 0.035 14.0 0.1 0.28 11.1 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Sigma70_ner PF04546.13 CAM39988.1 - 0.073 12.9 7.7 0.19 11.6 7.7 1.7 1 0 0 1 1 1 0 Sigma-70, non-essential region TPR_14 PF13428.6 CAM39988.1 - 0.21 12.5 2.8 0.42 11.6 0.0 3.2 3 0 0 3 3 1 0 Tetratricopeptide repeat DUF4404 PF14357.6 CAM39988.1 - 0.23 12.1 0.1 0.23 12.1 0.1 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4404) CMV_1a PF12467.8 CAM39988.1 - 0.45 10.8 4.4 0.2 12.0 0.4 2.4 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family AAA_2 PF07724.14 CAM39991.1 - 1.5e-55 187.9 0.1 3.8e-53 180.1 0.0 3.4 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CAM39991.1 - 2.1e-36 124.0 2.2 2.1e-36 124.0 2.2 2.7 2 0 0 2 2 2 1 AAA lid domain AAA PF00004.29 CAM39991.1 - 1.1e-26 93.9 0.0 9.6e-15 55.2 0.0 3.3 4 0 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CAM39991.1 - 1.4e-21 76.3 0.1 1.4e-21 76.3 0.1 3.4 4 0 0 4 4 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 CAM39991.1 - 3.4e-15 56.3 0.2 2.1e-10 40.7 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 CAM39991.1 - 4.8e-11 42.6 5.2 5.6e-05 23.2 1.5 3.2 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 CAM39991.1 - 5.5e-09 36.6 10.9 0.0015 18.9 0.1 5.3 4 2 1 5 5 4 2 AAA ATPase domain AAA_22 PF13401.6 CAM39991.1 - 5.9e-08 33.1 1.9 0.043 14.1 0.0 4.7 2 2 1 3 3 3 2 AAA domain Sigma54_activat PF00158.26 CAM39991.1 - 9.8e-08 31.9 0.0 6.3e-05 22.7 0.0 3.0 2 1 0 2 2 2 1 Sigma-54 interaction domain TniB PF05621.11 CAM39991.1 - 4.2e-07 29.6 0.0 0.0003 20.3 0.0 3.6 2 1 0 2 2 2 1 Bacterial TniB protein IstB_IS21 PF01695.17 CAM39991.1 - 5.2e-07 29.6 0.0 0.018 14.8 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 CAM39991.1 - 5.5e-07 29.7 0.0 0.029 14.4 0.0 3.5 4 0 0 4 4 2 2 AAA domain RuvB_N PF05496.12 CAM39991.1 - 2.5e-06 27.4 0.2 0.28 10.9 0.0 4.3 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 CAM39991.1 - 9.2e-06 25.3 0.0 0.049 13.1 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region ATPase_2 PF01637.18 CAM39991.1 - 6.5e-05 23.0 7.0 0.73 9.7 0.1 4.4 3 1 1 4 4 4 2 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 CAM39991.1 - 0.0001 21.7 0.1 0.09 12.1 0.0 3.7 3 0 0 3 3 3 1 Zeta toxin AAA_18 PF13238.6 CAM39991.1 - 0.00029 21.4 0.2 0.36 11.4 0.0 3.8 2 1 1 3 3 3 1 AAA domain NACHT PF05729.12 CAM39991.1 - 0.00049 20.1 0.0 0.096 12.6 0.0 3.1 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 CAM39991.1 - 0.00056 20.1 1.2 0.34 11.1 0.0 3.9 4 1 0 4 4 4 1 AAA domain Roc PF08477.13 CAM39991.1 - 0.00066 19.9 0.0 1.4 9.1 0.0 2.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 CAM39991.1 - 0.00071 19.6 0.0 2.5 8.1 0.0 2.9 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 CAM39991.1 - 0.00095 18.6 0.1 5.1 6.4 0.0 3.8 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 CAM39991.1 - 0.0012 18.1 0.1 0.3 10.2 0.1 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF815) ResIII PF04851.15 CAM39991.1 - 0.0012 18.8 0.0 0.23 11.4 0.0 3.7 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 CAM39991.1 - 0.0014 19.0 0.0 1.9 8.9 0.0 3.0 2 0 0 2 2 2 1 RNA helicase DNA_pol3_delta2 PF13177.6 CAM39991.1 - 0.0016 18.2 0.6 1.4 8.6 0.0 3.6 3 1 0 3 3 3 1 DNA polymerase III, delta subunit AAA_25 PF13481.6 CAM39991.1 - 0.0018 17.9 0.9 0.62 9.6 0.0 3.7 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.13 CAM39991.1 - 0.0041 16.4 0.0 0.85 8.8 0.0 3.0 2 1 1 3 3 3 1 TIP49 P-loop domain AAA_3 PF07726.11 CAM39991.1 - 0.0061 16.4 0.1 2.5 8.0 0.0 3.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CAM39991.1 - 0.0062 16.3 0.0 6.6 6.4 0.0 3.1 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CAM39991.1 - 0.0064 16.4 0.1 6.7 6.6 0.0 3.3 3 0 0 3 3 2 0 RsgA GTPase AAA_19 PF13245.6 CAM39991.1 - 0.0079 16.5 1.5 0.42 10.9 0.2 3.7 2 2 0 3 3 3 1 AAA domain ABC_tran PF00005.27 CAM39991.1 - 0.0098 16.4 1.1 16 6.0 0.0 3.9 4 0 0 4 4 3 0 ABC transporter AAA_29 PF13555.6 CAM39991.1 - 0.014 15.1 0.0 9.4 6.1 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_28 PF13521.6 CAM39991.1 - 0.041 14.1 0.1 15 5.8 0.0 3.3 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.15 CAM39991.1 - 0.049 13.5 2.7 2.1 8.2 0.0 3.3 4 0 0 4 4 3 0 NTPase Spc7 PF08317.11 CAM39991.1 - 0.13 11.2 12.5 0.25 10.2 12.5 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_23 PF13476.6 CAM39991.1 - 0.19 12.2 17.6 1.9 8.9 0.0 4.2 2 1 0 2 2 1 0 AAA domain V_ATPase_I PF01496.19 CAM39991.1 - 0.21 9.5 3.9 0.31 8.9 3.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6_N PF17675.1 CAM39991.1 - 1.1 9.8 11.7 4.1 7.9 11.7 2.1 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF16 PF01519.16 CAM39991.1 - 2 9.0 9.0 4.3 7.9 4.5 3.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 Lipase_3 PF01764.25 CAM39992.2 - 3.5e-24 85.3 0.0 8.5e-24 84.0 0.0 1.7 1 1 0 1 1 1 1 Lipase (class 3) MIG-14_Wnt-bd PF06664.12 CAM39992.2 - 1.4e-08 34.4 29.9 1.4e-08 34.4 29.9 1.8 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion PHO4 PF01384.20 CAM39992.2 - 0.24 10.4 4.8 15 4.5 0.1 2.3 1 1 0 2 2 2 0 Phosphate transporter family Tnp_P_element_C PF12596.8 CAM39993.1 - 0.084 13.4 0.5 0.15 12.6 0.2 1.7 1 1 1 2 2 2 0 87kDa Transposase DSS1_SEM1 PF05160.13 CAM39993.1 - 0.24 11.5 12.6 0.52 10.4 12.6 1.7 1 1 0 1 1 1 0 DSS1/SEM1 family Carn_acyltransf PF00755.20 CAM39995.1 - 8.8e-118 394.5 0.0 1.1e-117 394.2 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase RNA_pol_Rpc34 PF05158.12 CAM39996.1 - 1.6e-53 182.3 0.0 4e-53 180.9 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit TFIIE_alpha PF02002.17 CAM39996.1 - 0.038 13.8 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 TFIIE alpha subunit Pkinase PF00069.25 CAM39997.1 - 2.6e-62 210.6 0.0 9.1e-62 208.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM39997.1 - 2e-32 112.5 0.0 4e-23 82.0 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Haspin_kinase PF12330.8 CAM39997.1 - 0.0029 16.6 0.1 0.017 14.1 0.0 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 CAM39997.1 - 0.0033 16.8 0.4 0.0056 16.1 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CAM39997.1 - 0.022 14.7 0.4 0.051 13.5 0.4 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CAM39997.1 - 0.077 11.8 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RRM_1 PF00076.22 CAM40000.1 - 5e-31 106.3 0.0 4.8e-19 67.9 0.0 3.4 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAM40000.1 - 9.1e-05 22.5 0.0 0.0017 18.4 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif RRM_occluded PF16842.5 CAM40000.1 - 0.00035 20.4 0.0 0.52 10.2 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 CAM40000.1 - 0.0004 20.0 0.0 0.0014 18.2 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CAM40000.1 - 0.0011 19.1 0.1 0.016 15.2 0.0 2.7 2 1 1 3 3 3 1 Limkain b1 DUF4384 PF14326.6 CAM40000.1 - 0.076 13.1 1.8 0.35 11.0 0.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4384) RRM_3 PF08777.11 CAM40000.1 - 0.1 12.7 0.0 26 4.9 0.0 2.6 2 1 0 2 2 2 0 RNA binding motif RRM_Rrp7 PF17799.1 CAM40000.1 - 0.18 11.6 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain RRM_1 PF00076.22 CAM40002.1 - 4.2e-19 68.1 0.0 1.4e-11 44.0 0.1 3.7 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAM40002.1 - 0.0047 17.0 0.2 3.7 7.8 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif RNA_bind PF08675.11 CAM40002.1 - 0.016 15.3 0.0 0.27 11.3 0.0 2.4 2 0 0 2 2 2 0 RNA binding domain zf-LYAR PF08790.11 CAM40003.1 - 4.5e-13 48.8 3.7 4.5e-13 48.8 3.7 2.1 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 CAM40003.1 - 0.081 12.5 0.8 8.5 6.1 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-LYAR PF08790.11 CAM40004.1 - 1.7e-07 31.0 0.8 2.9e-07 30.3 0.8 1.4 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger DTHCT PF08070.11 CAM40004.1 - 0.26 12.0 2.6 0.88 10.3 2.6 2.0 1 1 0 1 1 1 0 DTHCT (NUC029) region RRM_1 PF00076.22 CAM40006.1 - 4.5e-25 87.3 0.0 1.2e-12 47.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CAM40006.1 - 0.015 14.9 0.2 0.63 9.6 0.1 2.4 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CAM40006.1 - 0.015 15.3 0.3 0.21 11.7 0.0 2.7 2 1 0 2 2 2 0 Limkain b1 RRM_7 PF16367.5 CAM40006.1 - 0.17 12.0 0.0 0.88 9.7 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif OrsD PF12013.8 CAM40006.1 - 0.24 11.9 3.1 0.31 11.5 1.8 1.9 1 1 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D RRM_1 PF00076.22 CAM40007.2 - 5.8e-26 90.1 0.1 5.5e-14 51.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAM40007.2 - 0.00051 20.1 0.0 0.077 13.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif PHM7_cyt PF14703.6 CAM40007.2 - 0.1 12.8 0.4 19 5.4 0.0 3.4 3 1 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Nab6_mRNP_bdg PF10567.9 CAM40007.2 - 0.12 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 RNA-recognition motif DUF4677 PF15726.5 CAM40008.1 - 0.034 14.3 0.2 0.068 13.3 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4677) TDP43_N PF18694.1 CAM40008.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Transactive response DNA-binding protein N-terminal domain Clat_adaptor_s PF01217.20 CAM40009.1 - 3.3e-50 169.7 0.9 3.9e-50 169.5 0.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PI3_PI4_kinase PF00454.27 CAM40010.2 - 3.3e-34 118.8 0.1 6.8e-31 108.0 0.1 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 CAM40010.2 - 4.1e-15 55.7 0.1 8e-15 54.7 0.1 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 CAM40010.2 - 0.03 13.7 0.0 0.065 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) P3A PF08727.11 CAM40010.2 - 0.23 10.9 0.2 0.88 9.0 0.1 2.0 2 0 0 2 2 2 0 Poliovirus 3A protein like Ank_2 PF12796.7 CAM40012.1 - 2.1e-06 28.2 0.0 4.5e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CAM40012.1 - 0.00011 22.7 0.1 0.00033 21.2 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 CAM40012.1 - 0.00071 19.8 0.2 0.023 15.0 0.1 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CAM40012.1 - 0.0091 16.4 0.0 0.97 10.2 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat DUF533 PF04391.12 CAM40012.1 - 0.055 13.0 0.3 0.055 13.0 0.3 2.3 3 1 0 3 3 3 0 Protein of unknown function (DUF533) Ank PF00023.30 CAM40012.1 - 0.06 13.8 0.4 2 9.0 0.1 2.6 2 0 0 2 2 2 0 Ankyrin repeat K_channel_TID PF07941.11 CAM40012.1 - 3 8.4 9.4 15 6.1 3.9 3.1 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Asn_synthase PF00733.21 CAM40014.1 - 4.2e-16 59.6 0.2 0.0016 18.1 0.0 4.2 3 1 1 4 4 4 3 Asparagine synthase SelP_N PF04592.14 CAM40014.1 - 0.34 10.3 3.2 0.54 9.6 3.2 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Nodulin-like PF06813.13 CAM40015.1 - 1.9e-10 40.7 11.5 1.9e-10 40.7 11.5 2.4 3 1 0 3 3 3 1 Nodulin-like Jiraiya PF15038.6 CAM40015.1 - 0.31 10.5 2.8 0.53 9.7 0.7 2.5 2 0 0 2 2 2 0 Jiraiya DUF373 PF04123.13 CAM40015.1 - 3.2 7.1 7.1 0.45 9.9 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF373) MFS_1 PF07690.16 CAM40016.1 - 4.4e-15 55.5 41.0 7.5e-13 48.1 22.1 2.8 2 1 0 3 3 3 3 Major Facilitator Superfamily Nodulin-like PF06813.13 CAM40016.1 - 1e-11 44.8 17.6 1e-11 44.8 17.6 2.2 2 1 0 2 2 2 1 Nodulin-like BCLP PF12304.8 CAM40016.1 - 0.12 11.9 5.8 0.043 13.4 0.7 2.7 2 1 1 3 3 3 0 Beta-casein like protein MFS_1 PF07690.16 CAM40017.1 - 8.9e-17 61.0 41.6 3.3e-14 52.6 22.2 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 CAM40017.1 - 1.8e-12 47.3 17.8 1.8e-12 47.3 17.8 2.4 2 1 0 2 2 2 1 Nodulin-like MotA_ExbB PF01618.16 CAM40017.1 - 0.17 11.7 0.9 1.2 8.9 0.1 2.8 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family BTK PF00779.19 CAM40020.2 - 0.076 12.8 0.5 0.24 11.3 0.5 1.8 1 0 0 1 1 1 0 BTK motif RabGAP-TBC PF00566.18 CAM40021.1 - 3.4e-44 151.1 0.0 4.6e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3135 PF11333.8 CAM40021.1 - 0.097 12.9 3.2 0.2 11.9 3.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) LisH PF08513.11 CAM40021.1 - 0.14 12.2 0.0 0.42 10.7 0.0 1.8 1 0 0 1 1 1 0 LisH Peptidase_M20 PF01546.28 CAM40022.1 - 1.9e-36 125.7 0.0 2.4e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CAM40022.1 - 3.8e-19 68.6 0.0 6.2e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain WD40 PF00400.32 CAM40023.2 - 3.2e-05 24.6 0.0 0.031 15.1 0.0 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM40023.2 - 0.00013 22.2 0.0 0.0014 18.9 0.0 2.4 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain XPC-binding PF09280.11 CAM40024.1 - 1.7e-06 27.6 3.3 3.6e-06 26.6 3.3 1.6 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.31 CAM40024.1 - 1.4e-05 24.9 0.6 7.6e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 UBA/TS-N domain MmoB_DmpM PF02406.17 CAM40024.1 - 0.016 15.4 0.4 9.4 6.5 0.0 2.6 2 0 0 2 2 2 0 MmoB/DmpM family EMP70 PF02990.16 CAM40027.2 - 1.1e-147 492.9 10.6 1.3e-147 492.6 10.6 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 SYS1 PF09801.9 CAM40028.1 - 2.4e-20 73.2 0.6 1.8e-17 63.8 0.1 2.2 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network dsrm PF00035.26 CAM40029.2 - 2e-09 38.0 0.0 0.74 10.6 0.0 5.8 5 0 0 5 5 5 4 Double-stranded RNA binding motif BUD22 PF09073.10 CAM40029.2 - 3.5 6.9 4.1 5.8 6.1 4.1 1.2 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 CAM40029.2 - 9 4.3 6.0 13 3.7 6.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi RINGv PF12906.7 CAM40030.1 - 3e-11 43.3 9.9 7e-11 42.1 9.9 1.7 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 CAM40030.1 - 0.051 13.9 7.8 0.096 13.0 7.8 1.5 1 0 0 1 1 1 0 Ring finger domain Phage_holin_2_4 PF16082.5 CAM40030.1 - 0.41 10.4 2.8 3.7 7.4 0.2 2.6 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like zf-RING-like PF08746.11 CAM40030.1 - 3.2 8.1 6.8 6.2 7.2 6.8 1.5 1 0 0 1 1 1 0 RING-like domain ABC_tran PF00005.27 CAM40031.1 - 4.5e-27 95.2 0.1 1.4e-26 93.6 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 CAM40031.1 - 1.3e-06 28.5 0.5 0.00024 21.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CAM40031.1 - 0.00041 19.9 0.0 0.009 15.5 0.0 2.1 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain T6SS_VipA PF05591.12 CAM40031.1 - 0.0043 16.9 0.2 0.0078 16.0 0.2 1.4 1 0 0 1 1 1 1 Type VI secretion system, VipA, VC_A0107 or Hcp2 T2SSE PF00437.20 CAM40031.1 - 0.023 13.8 0.0 0.039 13.0 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 CAM40031.1 - 0.037 13.8 0.0 3.2 7.4 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_29 PF13555.6 CAM40031.1 - 0.046 13.5 0.1 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 CAM40031.1 - 0.047 13.9 0.3 0.91 9.8 0.3 2.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 CAM40031.1 - 0.069 13.5 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 CAM40031.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 CAM40031.1 - 0.12 12.9 0.2 0.39 11.2 0.1 1.8 2 0 0 2 2 2 0 AAA domain Thioredoxin PF00085.20 CAM40032.2 - 9.7e-08 31.9 0.0 0.0002 21.3 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Redoxin PF08534.10 CAM40032.2 - 0.0032 17.2 0.7 0.016 14.9 0.0 2.3 3 0 0 3 3 3 1 Redoxin AhpC-TSA PF00578.21 CAM40032.2 - 0.021 14.7 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family DHR10 PF18595.1 CAM40033.2 - 0.011 15.7 2.9 0.011 15.7 2.9 1.7 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain FUSC PF04632.12 CAM40033.2 - 0.025 13.1 2.8 0.03 12.9 2.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Spc7 PF08317.11 CAM40033.2 - 0.22 10.4 2.6 0.12 11.2 0.7 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF948 PF06103.11 CAM40033.2 - 0.32 11.3 1.7 0.54 10.6 0.3 2.1 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ABC_tran_CTD PF16326.5 CAM40033.2 - 2.7 8.3 9.1 0.67 10.2 1.9 2.8 3 0 0 3 3 3 0 ABC transporter C-terminal domain PEP-utilisers_N PF05524.13 CAM40033.2 - 4.7 7.4 7.4 32 4.7 2.5 3.1 2 1 1 3 3 3 0 PEP-utilising enzyme, N-terminal 4HBT PF03061.22 CAM40034.1 - 2.2e-14 53.6 1.8 1.6e-09 38.0 0.6 2.4 2 0 0 2 2 2 2 Thioesterase superfamily MaoC_dehydratas PF01575.19 CAM40034.1 - 0.035 13.7 0.1 0.86 9.2 0.2 2.4 2 0 0 2 2 2 0 MaoC like domain 4HBT_2 PF13279.6 CAM40034.1 - 0.2 12.1 1.3 5.5 7.5 0.6 2.5 2 1 0 2 2 2 0 Thioesterase-like superfamily MORN PF02493.20 CAM40035.2 - 5e-53 173.9 94.0 3.1e-06 26.7 1.6 21.3 21 0 0 21 21 21 19 MORN repeat MutS_III PF05192.18 CAM40036.2 - 5.1e-18 66.0 0.0 9.4e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 MutS domain III MutS_V PF00488.21 CAM40036.2 - 1.6e-15 57.6 0.2 3.1e-08 33.9 0.1 2.6 2 0 0 2 2 2 2 MutS domain V AAA_30 PF13604.6 CAM40036.2 - 0.0089 15.8 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CAM40036.2 - 0.0092 15.7 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 CAM40036.2 - 0.021 15.2 0.1 0.08 13.3 0.1 2.0 1 0 0 1 1 1 0 AAA ATPase domain Histone_H2A_C PF16211.5 CAM40037.1 - 2.3e-09 36.8 0.7 4.6e-09 35.9 0.7 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CAM40037.1 - 1.3e-06 28.8 0.0 1.7e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CAM40037.1 - 0.0028 17.9 0.0 0.0048 17.2 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ribosomal_L29 PF00831.23 CAM40037.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal L29 protein Histone_H2A_C PF16211.5 CAM40038.1 - 2.3e-09 36.8 0.7 4.6e-09 35.9 0.7 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CAM40038.1 - 1.3e-06 28.8 0.0 1.7e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CAM40038.1 - 0.0028 17.9 0.0 0.0048 17.2 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ribosomal_L29 PF00831.23 CAM40038.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal L29 protein zf_C2H2_10 PF18414.1 CAM40040.1 - 0.017 14.6 0.1 0.026 14.1 0.1 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger zf-C2H2_12 PF18658.1 CAM40040.1 - 0.052 13.1 0.1 0.087 12.4 0.1 1.3 1 0 0 1 1 1 0 Zinc-finger C2H2-type zf-met2 PF12907.7 CAM40040.1 - 0.26 11.4 3.3 2.3 8.4 3.3 2.3 1 1 0 1 1 1 0 Zinc-binding DnaJ PF00226.31 CAM40042.1 - 3.8e-08 33.4 0.0 1e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain PCEMA1 PF07418.11 CAM40042.1 - 0.16 11.5 0.3 0.36 10.3 0.3 1.5 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 Rad50_zn_hook PF04423.14 CAM40043.1 - 0.15 11.9 1.2 0.31 10.9 0.2 1.9 2 0 0 2 2 2 0 Rad50 zinc hook motif Zn_ribbon_recom PF13408.6 CAM40043.1 - 0.25 11.9 1.5 0.55 10.8 1.5 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-C2H2_4 PF13894.6 CAM40043.1 - 1.2 10.2 4.6 3.7 8.6 4.6 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger PDEase_I_N PF08499.12 CAM40044.1 - 0.35 10.7 2.7 11 5.9 0.1 2.5 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal LigD_N PF13298.6 CAM40045.1 - 0.06 13.6 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase Ligase (LigD) EF-hand_7 PF13499.6 CAM40046.1 - 4.1e-13 49.6 0.0 0.00023 21.6 0.0 4.6 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 CAM40046.1 - 0.0001 21.9 0.0 0.76 9.9 0.0 4.1 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.32 CAM40046.1 - 0.01 15.4 2.0 0.42 10.3 0.1 4.0 5 0 0 5 5 5 0 EF hand EF-hand_13 PF17958.1 CAM40046.1 - 0.024 14.4 0.0 7.6 6.4 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain EF-hand_5 PF13202.6 CAM40046.1 - 2.5 7.8 3.6 2.7 7.6 0.1 2.7 3 0 0 3 3 3 0 EF hand PPTA PF01239.22 CAM40048.2 - 7.5e-18 63.6 14.5 7.2e-08 31.9 0.3 5.3 5 0 0 5 5 5 4 Protein prenyltransferase alpha subunit repeat HTH_Tnp_Tc5 PF03221.16 CAM40048.2 - 0.067 13.2 0.0 2.8 8.0 0.0 3.0 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain Fumerase_C PF05683.12 CAM40049.2 - 2.3e-89 298.1 0.0 3.9e-89 297.4 0.0 1.4 1 0 0 1 1 1 1 Fumarase C-terminus Fumerase PF05681.14 CAM40049.2 - 4.8e-80 268.9 0.0 6.2e-80 268.5 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Dehalogenase PF13486.6 CAM40050.2 - 0.22 10.9 0.6 0.65 9.3 0.0 2.1 2 0 0 2 2 2 0 Reductive dehalogenase subunit Fib_alpha PF08702.10 CAM40050.2 - 4.9 7.3 33.8 0.061 13.5 5.2 6.1 5 1 1 6 6 6 0 Fibrinogen alpha/beta chain family Methyltr_RsmB-F PF01189.17 CAM40053.1 - 4.7e-17 62.3 0.0 2.2e-07 30.7 0.0 3.6 3 0 0 3 3 3 3 16S rRNA methyltransferase RsmB/F PPR_2 PF13041.6 CAM40054.1 - 3.5e-06 27.1 0.0 0.0061 16.7 0.0 3.3 3 0 0 3 3 3 2 PPR repeat family PPR PF01535.20 CAM40054.1 - 0.016 15.4 0.0 15 6.1 0.0 3.9 5 0 0 5 5 5 0 PPR repeat PPR_3 PF13812.6 CAM40054.1 - 0.043 13.9 0.0 35 4.6 0.0 3.6 3 1 0 3 3 3 0 Pentatricopeptide repeat domain TetR_C_24 PF17932.1 CAM40054.1 - 0.05 13.9 0.5 0.18 12.1 0.5 2.0 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Pkinase PF00069.25 CAM40055.1 - 2e-73 247.0 0.0 2.8e-73 246.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM40055.1 - 5.9e-40 137.2 0.0 8.5e-40 136.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM40055.1 - 1.8e-06 27.5 0.0 6.9e-06 25.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 CAM40055.1 - 2.7e-05 23.9 0.2 0.00041 20.0 0.1 2.1 1 1 1 2 2 2 1 RIO1 family Kdo PF06293.14 CAM40055.1 - 0.00014 21.3 0.1 0.00024 20.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CAM40055.1 - 0.00068 18.7 0.1 0.0011 18.1 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CAM40055.1 - 0.003 17.5 0.5 0.16 11.9 0.1 2.6 3 0 0 3 3 3 1 Phosphotransferase enzyme family Gpi1 PF05024.15 CAM40056.1 - 1.6e-39 135.9 1.9 3.5e-39 134.8 1.9 1.6 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) DUF1249 PF06853.12 CAM40057.1 - 1.1 9.3 6.3 3.3 7.8 3.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1249) Cse1 PF08506.10 CAM40059.2 - 0.039 12.8 0.0 0.097 11.5 0.0 1.6 1 0 0 1 1 1 0 Cse1 HEAT PF02985.22 CAM40059.2 - 0.097 13.0 0.0 1.1 9.7 0.0 2.9 2 0 0 2 2 2 0 HEAT repeat adh_short PF00106.25 CAM40061.1 - 4.7e-05 22.9 0.0 0.00069 19.1 0.0 2.5 2 1 0 2 2 2 1 short chain dehydrogenase AAA_12 PF13087.6 CAM40063.2 - 6.4e-34 117.3 0.0 1e-33 116.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CAM40063.2 - 1.8e-13 50.9 6.6 3e-09 37.1 0.8 3.0 3 1 0 3 3 3 2 AAA domain AAA_30 PF13604.6 CAM40063.2 - 1.7e-07 31.1 1.7 0.0014 18.4 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 CAM40063.2 - 2.4e-05 24.7 0.4 0.35 11.2 0.0 3.2 2 1 0 2 2 2 2 AAA domain PhoH PF02562.16 CAM40063.2 - 0.0013 18.2 0.1 0.18 11.3 0.0 3.2 3 0 0 3 3 3 1 PhoH-like protein zf-C2H2_10 PF16588.5 CAM40063.2 - 0.0034 17.1 3.7 0.0077 15.9 3.7 1.6 1 0 0 1 1 1 1 C2H2 zinc-finger AAA_22 PF13401.6 CAM40063.2 - 0.005 17.1 0.1 1 9.7 0.0 3.6 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 CAM40063.2 - 0.018 14.8 1.2 2 8.1 0.0 3.2 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 CAM40063.2 - 0.019 14.3 0.0 0.039 13.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CSD PF00313.22 CAM40063.2 - 0.11 12.3 0.1 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain AAA_33 PF13671.6 CAM40063.2 - 4.8 7.3 6.9 5.2 7.2 0.0 3.8 4 0 0 4 4 4 0 AAA domain DUF4139 PF13598.6 CAM40064.2 - 2.2e-32 112.5 0.0 3.1e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) Glyco_transf_24 PF18404.1 CAM40065.2 - 4e-128 426.5 1.5 6e-128 425.9 1.5 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 CAM40065.2 - 5.2e-24 85.6 0.6 4.5e-22 79.2 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 CAM40065.2 - 3.3e-23 82.1 0.2 7.3e-21 74.5 0.0 3.2 3 0 0 3 3 3 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 CAM40065.2 - 5.6e-12 45.7 0.0 1.3e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_12 PF18400.1 CAM40065.2 - 6.2e-12 45.8 0.1 2e-11 44.1 0.1 1.9 1 0 0 1 1 1 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 CAM40065.2 - 7.3e-06 25.7 0.2 1.3e-05 24.9 0.2 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 VIT1 PF01988.19 CAM40066.2 - 1.2e-11 44.9 1.4 5.6e-11 42.7 1.4 1.9 1 1 0 1 1 1 1 VIT family LRR_4 PF12799.7 CAM40067.2 - 5.2e-15 55.3 12.0 0.0088 16.4 0.0 5.6 4 2 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM40067.2 - 2.3e-05 24.0 14.3 0.01 15.6 0.5 5.6 4 2 3 7 7 7 5 Leucine rich repeat LRR_6 PF13516.6 CAM40067.2 - 0.00079 19.3 11.5 14 6.0 0.0 7.6 10 0 0 10 10 10 2 Leucine Rich repeat LRR_1 PF00560.33 CAM40067.2 - 0.0068 16.8 18.6 21 6.2 0.3 7.7 7 2 0 7 7 7 1 Leucine Rich Repeat FNIP PF05725.12 CAM40067.2 - 0.15 12.2 6.2 2.2 8.5 0.1 3.9 3 1 1 4 4 4 0 FNIP Repeat ERG2_Sigma1R PF04622.12 CAM40068.1 - 7.5e-79 263.9 0.2 8.9e-79 263.7 0.2 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Pkinase PF00069.25 CAM40069.1 - 2.6e-37 128.6 0.0 9.1e-37 126.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM40069.1 - 2.3e-15 56.6 0.0 5.8e-15 55.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM40069.1 - 0.2 10.9 0.0 2.6 7.3 0.0 2.1 2 0 0 2 2 2 0 Kinase-like GDI PF00996.18 CAM40070.1 - 4.5e-177 588.9 0.0 5.2e-177 588.7 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 CAM40070.1 - 0.15 12.4 0.0 0.51 10.6 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DTW PF03942.15 CAM40071.2 - 8.9e-31 107.1 0.1 1.9e-30 106.0 0.1 1.5 1 0 0 1 1 1 1 DTW domain DUF4379 PF14311.6 CAM40072.2 - 2e-42 143.3 14.1 9.4e-16 57.9 1.0 3.4 3 0 0 3 3 3 3 Probable Zinc-ribbon domain HypA PF01155.19 CAM40072.2 - 3.5e-05 23.8 7.1 0.4 10.7 0.0 3.3 1 1 2 3 3 3 3 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 CAM40072.2 - 0.0008 19.5 10.2 0.18 11.9 0.1 3.6 3 0 0 3 3 3 3 Zinc ribbon domain DUF2072 PF09845.9 CAM40072.2 - 1.1 9.5 3.1 0.75 10.1 0.5 2.1 2 0 0 2 2 2 0 Zn-ribbon containing protein Zn_Tnp_IS91 PF14319.6 CAM40072.2 - 1.7 8.7 11.2 0.16 12.1 0.3 3.4 3 1 0 3 3 3 0 Transposase zinc-binding domain FeS_assembly_P PF01883.19 CAM40073.2 - 0.057 13.6 0.1 1.9 8.7 0.1 2.7 2 0 0 2 2 2 0 Iron-sulfur cluster assembly protein Dynamin_M PF01031.20 CAM40074.1 - 1.5e-81 273.8 0.2 3e-81 272.8 0.2 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 CAM40074.1 - 3.8e-50 170.2 0.1 1.2e-49 168.6 0.0 1.9 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 CAM40074.1 - 4.4e-25 87.7 0.3 1.5e-24 85.9 0.3 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 CAM40074.1 - 7.2e-05 22.8 0.2 0.00096 19.2 0.2 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 CAM40074.1 - 0.0019 18.0 1.5 0.48 10.1 0.0 2.7 3 0 0 3 3 3 2 AAA ATPase domain Baculo_p74 PF04583.12 CAM40074.1 - 0.019 14.5 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 Baculoviridae p74 conserved region AF0941-like PF14591.6 CAM40074.1 - 0.033 14.7 1.3 3.7 8.2 0.4 2.9 2 1 0 2 2 2 0 AF0941-like FeoB_N PF02421.18 CAM40074.1 - 0.038 13.5 0.9 4.2 6.9 0.0 2.9 3 0 0 3 3 3 0 Ferrous iron transport protein B p450 PF00067.22 CAM40074.1 - 0.069 11.9 0.2 0.14 10.9 0.0 1.6 2 0 0 2 2 2 0 Cytochrome P450 LRR_9 PF14580.6 CAM40075.2 - 3.4e-17 62.5 0.3 5.3e-17 61.9 0.3 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CAM40075.2 - 1.5e-11 44.3 1.6 4.4e-05 23.8 0.4 3.6 1 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM40075.2 - 3.7e-08 33.0 2.6 4.3e-07 29.6 0.4 3.0 3 0 0 3 3 3 1 Leucine rich repeat LRR_6 PF13516.6 CAM40075.2 - 0.0018 18.2 1.8 2.5 8.4 0.1 3.4 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.33 CAM40075.2 - 1 10.2 4.4 2.3e+02 3.0 0.0 4.4 3 1 1 4 4 4 0 Leucine Rich Repeat Serine_protease PF18405.1 CAM40077.2 - 0.007 15.6 0.7 0.18 10.9 0.1 2.2 2 0 0 2 2 2 2 Gammaproteobacterial serine protease ApbA PF02558.16 CAM40077.2 - 0.094 12.4 0.0 0.25 11.0 0.0 1.8 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_C PF07479.14 CAM40077.2 - 0.13 12.5 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Peptidase_M1 PF01433.20 CAM40078.1 - 6.8e-63 212.2 0.0 1.1e-62 211.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 CAM40078.1 - 1.3e-32 113.6 0.8 2e-32 113.0 0.8 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 CAM40078.1 - 3.1e-25 89.5 0.0 1.1e-24 87.7 0.0 1.8 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Tropomyosin PF00261.20 CAM40079.1 - 0.0039 16.6 4.7 0.0039 16.6 4.7 3.6 4 0 0 4 4 4 1 Tropomyosin DUF2968 PF11180.8 CAM40079.1 - 0.013 15.1 12.6 0.013 15.1 12.6 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2968) ERM PF00769.19 CAM40079.1 - 0.048 13.5 29.4 1 9.1 9.0 3.4 3 0 0 3 3 3 0 Ezrin/radixin/moesin family Phage_GP20 PF06810.11 CAM40079.1 - 0.35 10.7 23.1 0.028 14.2 7.0 3.3 3 0 0 3 3 3 0 Phage minor structural protein GP20 Filament PF00038.21 CAM40079.1 - 0.47 10.0 28.7 0.58 9.7 3.6 3.3 3 0 0 3 3 3 0 Intermediate filament protein Fez1 PF06818.15 CAM40079.1 - 0.49 10.8 23.0 0.34 11.3 0.7 3.4 3 0 0 3 3 3 0 Fez1 LMBR1 PF04791.16 CAM40079.1 - 0.5 9.2 5.6 0.19 10.6 2.0 1.9 2 0 0 2 2 2 0 LMBR1-like membrane protein Peptidase_M3_N PF08439.10 CAM40079.1 - 0.85 9.9 3.4 1.2 9.5 1.0 2.6 2 0 0 2 2 2 0 Oligopeptidase F Rootletin PF15035.6 CAM40079.1 - 0.97 9.4 21.7 0.077 13.0 3.6 3.3 3 0 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion HIP1_clath_bdg PF16515.5 CAM40079.1 - 1.3 9.7 34.2 0.51 11.0 4.3 3.9 4 0 0 4 4 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Leu_zip PF15294.6 CAM40079.1 - 1.7 8.1 24.9 0.15 11.6 1.9 3.2 3 0 0 3 3 3 0 Leucine zipper ADIP PF11559.8 CAM40079.1 - 2.2 8.4 38.8 0.46 10.5 4.4 3.8 4 0 0 4 4 3 0 Afadin- and alpha -actinin-Binding betaPIX_CC PF16523.5 CAM40079.1 - 2.7 7.9 10.6 1.4 8.8 1.0 2.8 2 1 0 2 2 2 0 betaPIX coiled coil Spc7 PF08317.11 CAM40079.1 - 3.6 6.4 25.4 0.84 8.5 0.9 3.4 3 0 0 3 3 3 0 Spc7 kinetochore protein GLE1 PF07817.13 CAM40079.1 - 4.2 6.5 12.3 9.9 5.3 4.5 3.3 3 0 0 3 3 3 0 GLE1-like protein APG6_N PF17675.1 CAM40079.1 - 4.5 7.8 47.1 2.1 8.9 13.8 4.1 4 0 0 4 4 4 0 Apg6 coiled-coil region Seryl_tRNA_N PF02403.22 CAM40079.1 - 4.6 7.5 23.5 0.24 11.6 0.4 4.3 3 2 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.10 CAM40079.1 - 4.7 7.4 15.0 1 9.5 2.3 3.5 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 CAM40079.1 - 5.5 7.5 8.7 26 5.3 0.8 3.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 CAM40079.1 - 5.9 7.0 15.7 0.52 10.4 2.1 4.1 5 0 0 5 5 4 0 Protein of unknown function (DUF1664) Lebercilin PF15619.6 CAM40079.1 - 6.3 6.4 30.8 0.76 9.4 7.2 3.5 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease FlxA PF14282.6 CAM40079.1 - 6.5 6.8 29.4 18 5.4 0.2 4.2 3 1 0 3 3 3 0 FlxA-like protein CHD5 PF04420.14 CAM40079.1 - 6.7 6.6 9.5 2.9 7.7 3.4 2.6 2 0 0 2 2 2 0 CHD5-like protein ACCA PF03255.14 CAM40079.1 - 8.6 6.2 12.8 2.3 8.1 0.4 3.3 3 0 0 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF3450 PF11932.8 CAM40079.1 - 9.3 5.5 29.7 0.19 11.0 7.6 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) SLD5_C PF16922.5 CAM40080.1 - 2.2e-08 34.2 0.0 3.5e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus MraY_sig1 PF10555.9 CAM40080.1 - 0.021 14.3 2.1 0.052 13.1 2.1 1.7 1 0 0 1 1 1 0 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 Sld5 PF05916.11 CAM40080.1 - 0.042 14.3 0.1 0.099 13.1 0.0 1.7 2 0 0 2 2 2 0 GINS complex protein Acyltransferase PF01553.21 CAM40081.1 - 1e-10 41.3 0.0 1.9e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase UCH PF00443.29 CAM40083.1 - 9.4e-43 146.6 0.0 1.6e-42 145.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CAM40083.1 - 1e-15 57.8 5.4 1e-15 57.8 5.4 3.8 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 CAM40083.1 - 3.4e-14 53.2 0.0 1.1e-13 51.5 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 CAM40083.1 - 3.6e-14 52.3 10.0 9.3e-13 47.7 8.4 2.7 2 0 0 2 2 2 1 Variant UBP zinc finger UBA PF00627.31 CAM40083.1 - 0.00027 20.8 0.1 0.00057 19.7 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain CUE PF02845.16 CAM40083.1 - 0.036 13.8 0.0 0.078 12.7 0.0 1.6 1 0 0 1 1 1 0 CUE domain UBA_4 PF14555.6 CAM40083.1 - 0.05 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain ECH_1 PF00378.20 CAM40084.1 - 9.2e-73 244.6 1.3 1.1e-72 244.4 1.3 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CAM40084.1 - 3.5e-36 125.4 1.7 2.4e-31 109.5 0.2 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 CAM40084.1 - 0.018 15.0 0.0 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 Peptidase family S49 Pkinase PF00069.25 CAM40085.1 - 3.1e-55 187.4 0.0 6e-55 186.4 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM40085.1 - 3.8e-35 121.4 0.0 6.5e-35 120.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CAM40085.1 - 1.7e-05 23.9 0.2 0.0045 16.0 0.0 2.9 3 0 0 3 3 3 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CAM40085.1 - 2.3e-05 23.4 0.0 4.1e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CAM40085.1 - 0.00031 20.7 0.0 0.087 12.7 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CAM40085.1 - 0.016 14.2 0.0 0.047 12.7 0.0 1.7 2 0 0 2 2 2 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.11 CAM40085.1 - 0.019 14.0 0.1 0.028 13.4 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pro-NT_NN PF07421.11 CAM40085.1 - 0.059 13.6 0.2 0.11 12.8 0.2 1.4 1 0 0 1 1 1 0 Neurotensin/neuromedin N precursor DUF1664 PF07889.12 CAM40086.1 - 0.023 14.7 4.5 0.27 11.3 0.1 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) NRN1 PF15056.6 CAM40086.1 - 0.092 12.8 0.1 0.26 11.4 0.1 1.9 1 1 0 1 1 1 0 Neuritin protein family STAT_alpha PF01017.20 CAM40086.1 - 1 9.2 6.3 15 5.4 0.6 2.6 2 1 1 3 3 3 0 STAT protein, all-alpha domain NAP PF00956.18 CAM40087.1 - 2.7e-08 33.3 2.9 0.0041 16.3 0.0 3.0 1 1 2 3 3 3 3 Nucleosome assembly protein (NAP) Phage_Mu_Gam PF07352.12 CAM40087.1 - 0.061 13.2 0.0 0.082 12.8 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein COQ7 PF03232.13 CAM40088.1 - 1.9e-53 180.7 0.1 2.2e-53 180.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Peptidase_M18 PF02127.15 CAM40089.1 - 8.6e-158 525.6 0.0 9.7e-158 525.5 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 CAM40089.1 - 8.3e-08 31.6 0.1 5.2e-05 22.4 0.1 2.2 1 1 0 2 2 2 2 M42 glutamyl aminopeptidase Ribosomal_L39 PF00832.20 CAM40090.1 - 3.4e-18 65.0 15.4 3.8e-18 64.8 15.4 1.0 1 0 0 1 1 1 1 Ribosomal L39 protein Kinesin PF00225.23 CAM40091.1 - 2.5e-85 286.3 0.7 4.1e-85 285.7 0.7 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CAM40091.1 - 2e-15 57.0 0.1 6.8e-15 55.3 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding STN1_2 PF09170.10 CAM40091.1 - 0.048 13.9 0.5 0.13 12.5 0.5 1.7 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 PRKG1_interact PF15898.5 CAM40091.1 - 1.6 9.7 7.9 0.4 11.6 0.8 2.7 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Kinesin PF00225.23 CAM40092.1 - 1.5e-92 310.1 0.1 1.8e-92 309.8 0.1 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CAM40092.1 - 1.6e-19 70.3 0.0 3.5e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding C2 PF00168.30 CAM40092.1 - 3.1e-05 24.2 0.0 7.8e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 C2 domain GAS PF13851.6 CAM40092.1 - 0.055 12.8 1.5 0.11 11.8 1.5 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding STN1_2 PF09170.10 CAM40092.1 - 0.062 13.5 0.5 0.15 12.2 0.5 1.6 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 Caldesmon PF02029.15 CAM40092.1 - 0.12 11.2 3.3 0.33 9.6 3.3 1.6 1 1 0 1 1 1 0 Caldesmon NIF PF03031.18 CAM40093.1 - 6.1e-32 110.6 0.0 8.5e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF705 PF05152.12 CAM40093.1 - 0.0016 18.0 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF705) Acyltransferase PF01553.21 CAM40094.1 - 1.1e-10 41.2 0.0 2e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase JmjN PF02375.17 CAM40094.1 - 0.028 14.4 0.1 0.057 13.4 0.1 1.5 1 0 0 1 1 1 0 jmjN domain ECF_trnsprt PF12822.7 CAM40094.1 - 0.079 13.1 3.5 0.15 12.1 3.5 1.5 1 0 0 1 1 1 0 ECF transporter, substrate-specific component PDEase_I PF00233.19 CAM40097.1 - 2.3e-74 250.1 1.8 6e-74 248.7 1.4 1.9 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Astro_capsid_N PF03115.14 CAM40097.1 - 0.0083 14.8 0.1 0.012 14.3 0.1 1.2 1 0 0 1 1 1 1 Astrovirus capsid protein precursor HSP20 PF00011.21 CAM40098.1 - 2.1e-17 63.1 0.0 2.5e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CAM40098.1 - 1.8e-09 37.0 0.0 4.1e-09 35.9 0.0 1.6 1 1 0 1 1 1 1 HSP20-like domain found in ArsA PapC_N PF13954.6 CAM40098.1 - 0.052 13.6 0.0 0.081 12.9 0.0 1.3 1 1 0 1 1 1 0 PapC N-terminal domain DDE_Tnp_1_2 PF13586.6 CAM40098.1 - 0.091 13.1 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain Ribosomal_L13e PF01294.18 CAM40099.1 - 3.6e-62 209.4 5.8 4.6e-62 209.1 5.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e PTPS PF01242.19 CAM40099.1 - 0.06 13.3 0.0 0.089 12.8 0.0 1.2 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase DUF4169 PF13770.6 CAM40099.1 - 0.062 13.6 0.3 0.062 13.6 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4169) Ribosomal_L13e PF01294.18 CAM40100.1 - 3.6e-62 209.4 5.8 4.6e-62 209.1 5.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e PTPS PF01242.19 CAM40100.1 - 0.06 13.3 0.0 0.089 12.8 0.0 1.2 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase DUF4169 PF13770.6 CAM40100.1 - 0.062 13.6 0.3 0.062 13.6 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4169) Pkinase PF00069.25 CAM40102.1 - 2.7e-42 144.9 0.0 3.9e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM40102.1 - 5.2e-35 121.0 0.0 6.9e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CAM40102.1 - 0.0042 16.1 0.1 0.0077 15.2 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CAM40102.1 - 0.0089 14.8 0.0 0.016 14.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 CAM40102.1 - 0.055 12.4 0.1 0.096 11.6 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 CAM40102.1 - 0.059 13.3 0.0 0.09 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family AAA PF00004.29 CAM40103.2 - 1.3e-39 135.6 0.0 3e-39 134.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 CAM40103.2 - 1e-24 86.2 0.1 2.6e-24 85.0 0.1 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 CAM40103.2 - 1.7e-16 60.0 3.7 1.7e-16 60.0 3.7 2.1 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 CAM40103.2 - 7.1e-09 35.3 0.3 2.7e-07 30.3 0.0 3.0 3 0 0 3 3 3 1 AAA+ lid domain AAA_2 PF07724.14 CAM40103.2 - 4.1e-06 27.0 0.0 1.2e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CAM40103.2 - 1.4e-05 25.6 0.2 0.00086 19.7 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 CAM40103.2 - 2.9e-05 24.4 0.1 0.0029 17.9 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CAM40103.2 - 8.1e-05 22.6 0.0 0.00042 20.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CAM40103.2 - 0.00049 19.9 0.0 0.0012 18.6 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 CAM40103.2 - 0.00059 19.6 0.0 0.0015 18.3 0.0 1.6 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 CAM40103.2 - 0.0011 19.2 0.0 0.0027 17.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CAM40103.2 - 0.0012 18.6 0.0 0.0029 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 CAM40103.2 - 0.0014 17.9 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain USP8_dimer PF08969.11 CAM40103.2 - 0.0019 18.4 3.3 0.0049 17.0 3.3 1.6 1 0 0 1 1 1 1 USP8 dimerisation domain DUF815 PF05673.13 CAM40103.2 - 0.0021 17.3 0.0 0.0035 16.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 CAM40103.2 - 0.0022 18.0 0.0 0.0088 16.1 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CAM40103.2 - 0.0044 17.6 0.0 0.017 15.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 CAM40103.2 - 0.0069 16.0 0.4 0.85 9.2 0.1 2.4 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.22 CAM40103.2 - 0.0092 16.4 0.0 0.023 15.1 0.0 1.7 1 0 0 1 1 1 1 RNA helicase ATPase_2 PF01637.18 CAM40103.2 - 0.0099 15.8 2.2 2.8 7.8 0.0 2.9 2 2 1 3 3 3 2 ATPase domain predominantly from Archaea AAA_17 PF13207.6 CAM40103.2 - 0.031 14.7 0.0 0.11 12.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain Viral_helicase1 PF01443.18 CAM40103.2 - 0.034 13.9 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 CAM40103.2 - 0.046 13.1 0.0 0.099 12.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI CPT PF07931.12 CAM40103.2 - 0.06 13.2 0.0 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Parvo_NS1 PF01057.17 CAM40103.2 - 0.069 12.2 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PPV_E1_C PF00519.17 CAM40103.2 - 0.071 11.9 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase AAA_7 PF12775.7 CAM40103.2 - 0.09 12.3 0.0 0.29 10.6 0.0 1.8 2 1 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 CAM40103.2 - 0.11 12.4 0.0 0.61 10.0 0.0 2.1 1 1 1 2 2 2 0 NACHT domain AFG1_ATPase PF03969.16 CAM40103.2 - 0.11 11.3 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase PhoH PF02562.16 CAM40103.2 - 0.16 11.4 0.2 0.32 10.4 0.2 1.4 1 0 0 1 1 1 0 PhoH-like protein PFK PF00365.20 CAM40104.1 - 4.3e-63 213.3 0.5 5.4e-63 213.0 0.5 1.1 1 0 0 1 1 1 1 Phosphofructokinase DAGK_cat PF00781.24 CAM40104.1 - 0.00035 20.2 0.2 0.00086 18.9 0.0 1.7 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 CAM40104.1 - 0.04 13.1 0.0 0.058 12.6 0.0 1.3 1 0 0 1 1 1 0 ATP-NAD kinase zf-MIZ PF02891.20 CAM40105.1 - 7.8e-09 35.2 0.3 2.9e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 CAM40105.1 - 0.16 11.8 0.1 0.39 10.6 0.1 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit TPR_19 PF14559.6 CAM40108.1 - 4.8e-22 78.2 22.0 3.7e-05 24.1 2.4 8.7 7 2 2 9 9 9 7 Tetratricopeptide repeat TPR_14 PF13428.6 CAM40108.1 - 4.7e-13 48.8 40.6 0.00083 20.0 0.2 10.9 9 2 3 12 12 10 5 Tetratricopeptide repeat TPR_2 PF07719.17 CAM40108.1 - 7.3e-09 35.1 23.2 0.16 12.1 0.0 11.4 12 0 0 12 12 12 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 CAM40108.1 - 1.5e-08 34.3 19.8 0.00094 18.8 1.8 5.9 6 1 1 7 7 7 2 Bacterial type III secretion protein (HrpB1_HrpK) TPR_16 PF13432.6 CAM40108.1 - 2.7e-08 34.3 35.9 0.039 14.6 2.3 8.4 7 2 3 10 10 9 5 Tetratricopeptide repeat ANAPC3 PF12895.7 CAM40108.1 - 2.9e-07 30.6 14.1 0.27 11.5 0.4 5.9 6 0 0 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 CAM40108.1 - 1.7e-05 24.4 3.3 0.65 9.9 0.0 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 CAM40108.1 - 0.00013 22.1 35.5 0.45 10.8 2.9 9.8 9 2 1 10 10 10 2 Tetratricopeptide repeat TPR_4 PF07721.14 CAM40108.1 - 0.0014 19.1 38.4 0.35 11.6 0.7 10.6 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_6 PF13174.6 CAM40108.1 - 0.0039 17.7 19.4 0.17 12.6 0.0 8.8 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_17 PF13431.6 CAM40108.1 - 0.0073 16.6 14.0 67 4.2 0.0 8.2 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_20 PF14561.6 CAM40108.1 - 0.008 16.5 7.0 0.028 14.8 0.4 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 CAM40108.1 - 0.013 15.1 6.7 1.2 8.8 0.0 5.2 6 0 0 6 6 6 0 TPR repeat NatB_MDM20 PF09797.9 CAM40108.1 - 0.025 13.5 0.2 0.025 13.5 0.2 2.5 3 0 0 3 3 3 0 N-acetyltransferase B complex (NatB) non catalytic subunit Topoisom_bac PF01131.20 CAM40108.1 - 0.052 12.5 0.1 0.099 11.6 0.1 1.4 1 0 0 1 1 1 0 DNA topoisomerase Fis1_TPR_C PF14853.6 CAM40108.1 - 0.12 12.4 3.2 17 5.6 0.0 4.9 7 0 0 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat Coatomer_E PF04733.14 CAM40108.1 - 0.34 10.3 8.3 19 4.5 0.4 5.1 5 2 2 7 7 7 0 Coatomer epsilon subunit TPR_9 PF13371.6 CAM40108.1 - 1.2 9.3 17.2 9.6 6.4 0.4 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 CAM40108.1 - 2 8.6 10.3 53 4.2 0.0 6.5 8 0 0 8 8 7 0 Tetratricopeptide repeat DUF4586 PF15239.6 CAM40109.1 - 4.6e-67 227.4 11.2 5.4e-67 227.1 11.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) Pkinase PF00069.25 CAM40110.1 - 1e-65 221.7 0.0 1.6e-65 221.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM40110.1 - 6.3e-45 153.5 0.0 1.7e-44 152.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM40110.1 - 9.2e-06 25.2 0.1 1.8e-05 24.2 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CAM40110.1 - 0.0058 16.6 0.1 1.7 8.5 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CAM40110.1 - 0.027 13.3 0.1 0.072 11.8 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Ribos_L4_asso_C PF14374.6 CAM40110.1 - 0.04 14.0 1.7 0.04 14.0 0.2 1.8 2 0 0 2 2 2 0 60S ribosomal protein L4 C-terminal domain KHA PF11834.8 CAM40112.1 - 0.035 14.2 0.0 3.7 7.7 0.0 2.6 2 0 0 2 2 2 0 KHA, dimerisation domain of potassium ion channel PAP_central PF04928.17 CAM40113.1 - 4.6e-35 120.8 0.0 6.2e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 CAM40113.1 - 2e-06 27.5 0.0 3.1e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain GAS PF13851.6 CAM40114.2 - 0.0087 15.4 5.9 0.033 13.5 5.9 2.0 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Mei5 PF10376.9 CAM40114.2 - 0.24 11.2 7.6 0.022 14.6 1.9 2.1 3 0 0 3 3 3 0 Double-strand recombination repair protein Lectin_N PF03954.14 CAM40114.2 - 0.28 10.9 7.5 0.064 13.0 0.8 3.0 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain Noelin-1 PF12308.8 CAM40114.2 - 0.38 10.8 3.3 1.1 9.3 2.2 2.4 2 0 0 2 2 2 0 Neurogenesis glycoprotein FlaC_arch PF05377.11 CAM40114.2 - 1.1 9.7 7.1 52 4.3 0.2 5.0 6 0 0 6 6 6 0 Flagella accessory protein C (FlaC) Csm1_N PF18504.1 CAM40114.2 - 2.8 8.4 6.3 5.5 7.4 0.6 3.6 1 1 1 2 2 2 0 Csm1 N-terminal domain DUF4600 PF15372.6 CAM40114.2 - 3.4 8.1 7.2 0.42 11.1 1.5 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4600) KASH_CCD PF14662.6 CAM40114.2 - 3.9 7.3 14.3 0.22 11.3 6.7 2.7 3 0 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH PrgI PF12666.7 CAM40115.1 - 0.13 13.0 0.1 0.17 12.6 0.1 1.2 1 0 0 1 1 1 0 PrgI family protein SAM_1 PF00536.30 CAM40116.2 - 3.6e-05 24.1 0.0 0.0001 22.6 0.0 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CAM40116.2 - 0.037 14.1 0.0 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 CAM40116.2 - 0.044 13.7 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain DinB_2 PF12867.7 CAM40116.2 - 3.1 8.3 9.4 7.9 7.0 0.1 5.5 4 2 0 4 4 4 0 DinB superfamily Arm PF00514.23 CAM40117.1 - 0.0041 17.1 4.0 1.3 9.2 0.1 4.0 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Scaffolding_pro PF11418.8 CAM40117.1 - 0.097 13.2 0.0 0.2 12.3 0.0 1.5 1 0 0 1 1 1 0 Phi29 scaffolding protein Cnd3 PF12719.7 CAM40118.1 - 2.7e-37 128.6 0.7 2.7e-37 128.6 0.7 2.0 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Cnd1 PF12717.7 CAM40118.1 - 5.9e-08 32.9 0.3 0.043 13.8 0.2 4.5 3 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CAM40118.1 - 5.9e-07 29.8 4.2 0.00011 22.5 0.6 6.2 5 1 2 7 7 7 3 HEAT repeats HEAT PF02985.22 CAM40118.1 - 0.00011 22.1 13.0 1.8 9.0 0.0 6.6 6 0 0 6 6 6 3 HEAT repeat SspB PF04386.13 CAM40118.1 - 0.04 13.8 0.2 12 5.8 0.0 2.8 3 0 0 3 3 3 0 Stringent starvation protein B RTP1_C1 PF10363.9 CAM40118.1 - 0.058 13.6 0.1 2.3 8.4 0.0 3.2 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Helicase_C_2 PF13307.6 CAM40119.1 - 1e-48 165.8 0.0 3e-48 164.2 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 CAM40119.1 - 1.5e-44 151.7 0.2 1.6e-43 148.4 0.0 2.2 2 0 0 2 2 2 1 DEAD_2 DEAD PF00270.29 CAM40119.1 - 1.3e-05 25.1 0.0 0.0018 18.1 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 CAM40119.1 - 8.4e-05 22.6 0.0 0.013 15.5 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit HBB PF06777.11 CAM40119.1 - 0.0033 17.1 0.0 0.0085 15.8 0.0 1.6 1 0 0 1 1 1 1 Helical and beta-bridge domain AAA_11 PF13086.6 CAM40119.1 - 0.042 13.6 0.2 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 CAM40120.1 - 3.7e-62 210.1 0.0 5e-62 209.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM40120.1 - 5.3e-40 137.3 0.0 7.3e-40 136.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CAM40120.1 - 0.0003 20.8 0.1 0.084 12.8 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CAM40120.1 - 0.00041 19.2 0.0 0.00041 19.2 0.0 2.3 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 CAM40120.1 - 0.00092 18.6 0.0 0.0024 17.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 CAM40120.1 - 0.036 13.7 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 CAM40120.1 - 0.14 11.1 0.2 14 4.5 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain DUF4200 PF13863.6 CAM40121.1 - 5e-23 81.8 21.6 5e-23 81.8 21.6 3.7 3 1 0 3 3 3 1 Domain of unknown function (DUF4200) Ribonuc_red_2_N PF08471.10 CAM40121.1 - 0.056 13.6 3.9 0.15 12.3 3.5 2.0 1 1 0 1 1 1 0 Class II vitamin B12-dependent ribonucleotide reductase DUF3918 PF13056.6 CAM40121.1 - 0.061 12.9 0.2 0.21 11.2 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) HTH_26 PF13443.6 CAM40121.1 - 0.39 11.2 2.5 3.1 8.3 0.6 2.7 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain Spc7 PF08317.11 CAM40121.1 - 0.57 9.0 30.1 1.2 7.9 9.0 2.6 1 1 1 2 2 2 0 Spc7 kinetochore protein MCD_N PF17408.2 CAM40121.1 - 0.78 9.9 5.6 0.28 11.3 2.0 2.3 2 1 0 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain AATF-Che1 PF13339.6 CAM40121.1 - 4.6 7.9 23.5 0.3 11.8 4.6 3.3 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor KMP11 PF03037.16 CAM40121.1 - 6.8 7.6 11.8 8.4 7.3 0.9 3.1 4 0 0 4 4 4 0 Kinetoplastid membrane protein 11 TACC_C PF05010.14 CAM40121.1 - 8.2 6.2 33.5 1.8 8.3 27.7 2.4 2 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal zf-RING_5 PF14634.6 CAM40122.1 - 2.2e-05 24.3 9.4 7.5e-05 22.6 9.4 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CAM40122.1 - 0.00059 19.6 9.8 0.0015 18.3 9.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CAM40122.1 - 0.0019 18.1 9.3 0.0058 16.5 9.3 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DASH_Dad2 PF08654.10 CAM40122.1 - 0.088 13.2 0.4 0.16 12.4 0.4 1.4 1 0 0 1 1 1 0 DASH complex subunit Dad2 GAS PF13851.6 CAM40122.1 - 0.12 11.8 2.2 0.19 11.0 2.2 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TP_methylase PF00590.20 CAM40122.1 - 0.14 12.1 1.9 0.25 11.2 1.9 1.3 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF720 PF05302.11 CAM40122.1 - 0.28 11.1 3.0 0.52 10.2 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF720) DUF1192 PF06698.11 CAM40122.1 - 0.31 11.1 2.0 0.37 10.9 0.6 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF1192) FAM92 PF06730.11 CAM40122.1 - 0.34 10.3 2.6 0.49 9.8 2.6 1.1 1 0 0 1 1 1 0 FAM92 protein zf-C3HC4 PF00097.25 CAM40122.1 - 0.6 10.0 14.4 0.026 14.4 8.4 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF1848 PF08902.11 CAM40122.1 - 1.2 8.8 6.0 0.32 10.7 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1848) zf-RING_4 PF14570.6 CAM40122.1 - 1.8 8.5 12.7 1.1 9.1 10.3 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain ERM PF00769.19 CAM40122.1 - 3.6 7.3 10.6 5.5 6.7 10.6 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family SlyX PF04102.12 CAM40122.1 - 8.5 7.1 9.5 72 4.1 4.5 2.9 2 1 1 3 3 3 0 SlyX Ras PF00071.22 CAM40123.1 - 1.7e-51 174.0 0.0 2.1e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAM40123.1 - 2.7e-33 114.7 0.0 4e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAM40123.1 - 3.6e-12 46.1 0.0 5.1e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CAM40123.1 - 3.4e-07 29.9 0.0 4.5e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CAM40123.1 - 2e-06 27.8 0.1 0.0041 17.0 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CAM40123.1 - 7.2e-06 26.1 0.0 1.2e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CAM40123.1 - 3.1e-05 24.4 0.1 4e-05 24.1 0.1 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CAM40123.1 - 0.0022 18.3 0.0 0.0043 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 CAM40123.1 - 0.0038 16.8 0.0 0.017 14.7 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_5 PF07728.14 CAM40123.1 - 0.015 15.3 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 CAM40123.1 - 0.015 15.2 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 CAM40123.1 - 0.016 14.7 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 CAM40123.1 - 0.027 14.5 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 CAM40123.1 - 0.031 14.0 0.0 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 CAM40123.1 - 0.052 12.7 0.3 0.46 9.6 0.1 2.0 1 1 1 2 2 2 0 G-protein alpha subunit ABC_tran PF00005.27 CAM40123.1 - 0.073 13.6 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 CAM40123.1 - 0.082 13.3 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 CAM40123.1 - 0.13 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain SRPRB PF09439.10 CAM40123.1 - 0.2 11.0 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Lipase_3 PF01764.25 CAM40124.1 - 4e-14 52.7 0.0 1.1e-13 51.2 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) UPF0227 PF05728.12 CAM40124.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Adeno_PV PF03910.13 CAM40124.1 - 0.55 8.9 5.6 1.5 7.5 5.6 1.7 1 0 0 1 1 1 0 Adenovirus minor core protein PV Lipase_3 PF01764.25 CAM40125.2 - 1.5e-14 54.0 0.0 2.8e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.12 CAM40125.2 - 0.037 14.0 0.0 0.068 13.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Tubulin_C PF03953.17 CAM40126.1 - 8e-50 168.2 0.0 1.1e-49 167.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Acetyltransf_1 PF00583.25 CAM40128.1 - 2.5e-13 50.3 0.2 4.7e-13 49.4 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.10 CAM40128.1 - 2e-07 30.9 0.0 3.2e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 CAM40128.1 - 4.1e-07 30.0 0.2 8.4e-07 29.0 0.2 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CAM40128.1 - 1e-05 25.8 0.1 2.3e-05 24.7 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 CAM40128.1 - 0.0022 17.5 0.3 0.0026 17.3 0.3 1.2 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_4 PF13420.7 CAM40128.1 - 0.009 16.2 0.4 0.014 15.5 0.4 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF5596 PF18082.1 CAM40128.1 - 0.022 14.6 0.1 0.053 13.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5596) Acetyltransf_9 PF13527.7 CAM40128.1 - 0.053 13.6 0.2 0.053 13.6 0.2 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain ANAPC4_WD40 PF12894.7 CAM40129.1 - 0.074 13.4 0.1 4.2 7.7 0.1 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PDEase_I PF00233.19 CAM40130.1 - 1.1e-47 162.8 1.6 1.9e-47 162.0 0.0 2.3 2 1 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase FYVE PF01363.21 CAM40130.1 - 1.1e-07 31.9 13.6 2.2e-07 30.9 13.6 1.5 1 0 0 1 1 1 1 FYVE zinc finger Glu-tRNAGln PF02686.15 CAM40130.1 - 0.0095 16.2 0.5 0.0095 16.2 0.5 3.7 4 0 0 4 4 4 1 Glu-tRNAGln amidotransferase C subunit Esterase_phd PF10503.9 CAM40131.1 - 3.7 7.0 6.2 0.55 9.7 1.0 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase Beta_helix PF13229.6 CAM40133.1 - 4.6e-19 68.8 1.1 3.5e-15 56.2 0.1 2.1 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 CAM40133.1 - 6.5e-09 35.4 0.0 9e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Pectate_lyase_3 PF12708.7 CAM40133.1 - 0.075 12.9 0.2 2.3 8.0 0.0 2.6 1 1 2 3 3 3 0 Pectate lyase superfamily protein Pkinase PF00069.25 CAM40134.1 - 3.9e-36 124.8 0.0 3.5e-35 121.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM40134.1 - 3.4e-15 56.0 0.0 8.3e-15 54.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CAM40134.1 - 0.00027 20.4 0.0 0.00052 19.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family START PF01852.19 CAM40135.1 - 5.8e-28 97.7 0.0 9.7e-28 97.0 0.0 1.2 1 0 0 1 1 1 1 START domain DUF3074 PF11274.8 CAM40135.1 - 0.0017 18.4 0.0 0.013 15.5 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3074) Actin PF00022.19 CAM40136.1 - 2e-19 69.5 0.0 4.2e-13 48.7 0.0 2.4 1 1 0 2 2 2 2 Actin TPR_19 PF14559.6 CAM40138.1 - 4.2e-10 40.0 2.1 0.0071 16.8 0.1 4.7 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 CAM40138.1 - 3.7e-08 32.9 21.7 0.036 14.2 0.2 6.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 CAM40138.1 - 4.8e-08 33.5 1.9 0.068 13.8 0.0 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CAM40138.1 - 9.9e-06 25.7 17.0 0.032 14.5 0.7 5.0 4 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 CAM40138.1 - 0.00023 20.8 16.1 0.15 11.9 0.3 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 CAM40138.1 - 0.00076 20.1 4.8 10 7.3 0.0 5.2 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 CAM40138.1 - 0.00099 18.7 1.6 0.2 11.4 0.1 2.9 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.6 CAM40138.1 - 0.0012 19.1 9.7 0.78 10.1 0.2 5.2 4 2 0 4 4 4 1 Tetratricopeptide repeat DUF4993 PF16384.5 CAM40138.1 - 0.0059 15.7 0.1 0.011 14.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function TPR_7 PF13176.6 CAM40138.1 - 0.05 13.7 1.6 2.3 8.4 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 CAM40138.1 - 0.6 10.2 14.2 1.1 9.3 0.2 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 CAM40138.1 - 1.5 9.2 13.3 21 5.7 0.1 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 CAM40138.1 - 7.4 7.4 10.5 13 6.7 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Trypsin_2 PF13365.6 CAM40139.1 - 0.011 16.6 4.2 0.028 15.3 4.2 1.6 1 1 0 1 1 1 0 Trypsin-like peptidase domain Mito_carr PF00153.27 CAM40140.1 - 7.1e-58 192.5 0.3 2e-19 69.3 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein ThrE_2 PF12821.7 CAM40140.1 - 0.0058 16.8 0.3 0.91 9.7 0.1 2.4 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE IU_nuc_hydro PF01156.19 CAM40141.2 - 2.7e-42 145.4 0.2 3.6e-42 145.0 0.2 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase LRR_6 PF13516.6 CAM40143.1 - 1.9e-27 92.9 32.1 0.0072 16.3 0.3 14.0 14 0 0 14 14 14 7 Leucine Rich repeat LRR_1 PF00560.33 CAM40143.1 - 1.1e-08 34.4 0.7 34 5.5 0.0 9.1 10 0 0 10 10 9 0 Leucine Rich Repeat LRR_4 PF12799.7 CAM40143.1 - 4.4e-06 26.9 11.8 1.9 9.0 0.1 6.7 7 0 0 7 7 7 2 Leucine Rich repeats (2 copies) DUF489 PF04356.12 CAM40143.1 - 0.0046 17.0 0.8 0.011 15.7 0.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF489) AAA_13 PF13166.6 CAM40143.1 - 0.069 11.8 9.9 0.098 11.3 9.9 1.1 1 0 0 1 1 1 0 AAA domain LRR_8 PF13855.6 CAM40143.1 - 0.35 10.7 23.3 1.5 8.6 0.8 7.3 5 4 0 6 6 6 0 Leucine rich repeat DUF3450 PF11932.8 CAM40143.1 - 0.73 9.1 13.1 3.4 6.9 6.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) PIEZO PF15917.5 CAM40143.1 - 1 8.8 5.1 2.1 7.7 5.1 1.4 1 0 0 1 1 1 0 Piezo Prominin PF05478.11 CAM40143.1 - 1.7 6.5 5.3 2.5 5.9 5.3 1.2 1 0 0 1 1 1 0 Prominin Occludin_ELL PF07303.13 CAM40143.1 - 2.2 9.1 5.2 3.1 8.6 3.4 2.1 1 1 0 1 1 1 0 Occludin homology domain DUF4407 PF14362.6 CAM40143.1 - 2.7 7.2 12.0 5.7 6.2 11.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 CAM40143.1 - 5.1 7.2 7.2 11 6.1 1.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 CAM40143.1 - 8.9 6.5 6.9 9.4 6.4 5.3 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family RRM_1 PF00076.22 CAM40145.1 - 1.9e-18 66.0 0.0 2.7e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CAM40145.1 - 0.054 13.1 0.0 0.094 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metaviral_G PF09595.10 CAM40145.1 - 0.12 12.4 5.2 0.1 12.6 3.8 1.5 2 0 0 2 2 2 0 Metaviral_G glycoprotein CENP-T_C PF15511.6 CAM40146.1 - 1.9e-05 24.8 0.1 3e-05 24.1 0.0 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CAM40146.1 - 0.002 18.3 0.3 0.003 17.8 0.0 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 CAM40146.1 - 0.0025 17.9 0.1 0.004 17.3 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 CAM40146.1 - 0.0046 16.9 0.0 0.0054 16.7 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 CAM40146.1 - 0.011 16.1 1.5 0.022 15.1 1.5 1.5 1 1 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CAM40146.1 - 0.15 12.1 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit PCP_red PF08369.10 CAM40146.1 - 0.33 11.2 1.6 1.4 9.2 0.1 2.4 2 1 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit LRR_4 PF12799.7 CAM40147.1 - 0.00083 19.7 0.0 7.7 7.1 0.0 3.7 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) RRM_1 PF00076.22 CAM40148.2 - 1.4e-20 72.9 0.0 2.6e-09 36.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Myosin_TH1 PF06017.13 CAM40149.2 - 0.086 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Unconventional myosin tail, actin- and lipid-binding Hydrolase_4 PF12146.8 CAM40151.1 - 2.3e-07 30.3 0.0 3e-06 26.7 0.0 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CAM40151.1 - 1.3e-06 29.1 2.2 1.3e-06 29.1 2.2 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CAM40151.1 - 2e-06 27.6 0.2 0.00011 22.0 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Pro_isomerase PF00160.21 CAM40152.1 - 1.1e-19 71.3 0.0 7.3e-19 68.6 0.0 2.0 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD UPF0220 PF05255.11 CAM40154.1 - 9.6e-18 64.3 0.1 1.2e-17 63.9 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF3267 PF11667.8 CAM40154.1 - 0.013 15.8 0.4 0.028 14.7 0.1 1.8 1 1 1 2 2 2 0 Putative zincin peptidase EamA PF00892.20 CAM40154.1 - 0.013 15.6 3.5 0.019 15.1 3.5 1.3 1 0 0 1 1 1 0 EamA-like transporter family COPI_assoc PF08507.10 CAM40154.1 - 1.6 8.8 6.9 6.1 6.9 6.9 1.8 1 1 0 1 1 1 0 COPI associated protein MATH PF00917.26 CAM40155.1 - 6.7e-07 29.5 0.5 2.2e-06 27.8 0.5 2.0 1 0 0 1 1 1 1 MATH domain CorA PF01544.18 CAM40155.1 - 0.46 9.7 12.9 1.1 8.5 12.9 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein REF PF05755.12 CAM40155.1 - 6.1 6.6 9.2 28 4.4 9.2 2.1 1 1 0 1 1 1 0 Rubber elongation factor protein (REF) SHR3_chaperone PF08229.11 CAM40156.1 - 0.23 10.4 0.0 0.39 9.7 0.0 1.3 1 0 0 1 1 1 0 ER membrane protein SH3 COX1 PF00115.20 CAM40157.1 - 0.0039 16.1 0.7 0.0048 15.8 0.7 1.1 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Cyclin_N PF00134.23 CAM40158.1 - 6.3e-24 84.1 0.4 2.1e-23 82.5 0.1 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain TERF2_RBM PF16772.5 CAM40158.1 - 0.0097 15.3 0.0 0.026 13.9 0.0 1.7 1 0 0 1 1 1 1 Telomeric repeat-binding factor 2 Rap1-binding motif FoP_duplication PF13865.6 CAM40159.1 - 6.2e-05 23.5 8.3 6.2e-05 23.5 8.3 4.1 2 1 2 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 LRR_4 PF12799.7 CAM40161.1 - 5.2e-10 39.4 9.7 0.0015 18.9 0.1 4.7 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM40161.1 - 0.00025 20.8 15.8 0.061 13.1 0.1 5.3 6 0 0 6 6 6 2 Leucine rich repeat LRR_1 PF00560.33 CAM40161.1 - 0.01 16.2 5.4 31 5.6 0.0 5.5 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 CAM40161.1 - 0.059 13.5 10.8 27 5.2 0.1 5.8 6 0 0 6 6 6 0 Leucine Rich repeat FAD-oxidase_C PF02913.19 CAM40162.1 - 6.7e-49 166.8 0.0 2.2e-48 165.1 0.0 1.7 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CAM40162.1 - 3.1e-37 127.4 0.0 6.3e-37 126.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain tRNA-synt_2 PF00152.20 CAM40163.1 - 4.1e-78 262.6 0.0 5.2e-78 262.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CAM40163.1 - 5.1e-07 29.6 0.0 9.5e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CAM40163.1 - 5.1e-07 29.4 0.1 0.00029 20.4 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Yip1 PF04893.17 CAM40164.1 - 7.4e-11 42.1 14.9 1.2e-10 41.3 14.5 1.5 1 1 0 1 1 1 1 Yip1 domain CCSMST1 PF15013.6 CAM40164.1 - 0.14 12.3 0.2 0.35 11.1 0.2 1.6 1 0 0 1 1 1 0 CCSMST1 family LRR_6 PF13516.6 CAM40165.1 - 4.2e-44 144.9 11.7 1.6e-06 27.7 0.2 9.4 9 0 0 9 9 9 8 Leucine Rich repeat LRR_4 PF12799.7 CAM40165.1 - 4.8e-12 45.9 8.5 0.00042 20.6 0.2 5.8 2 2 5 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM40165.1 - 2.7e-07 30.2 12.4 0.37 10.6 3.0 6.6 4 3 1 5 5 5 3 Leucine rich repeat LRR_1 PF00560.33 CAM40165.1 - 2e-06 27.5 3.6 1.6 9.6 0.0 7.0 8 0 0 8 8 8 1 Leucine Rich Repeat LRR_9 PF14580.6 CAM40165.1 - 0.0074 15.8 0.1 0.62 9.6 0.0 2.6 2 0 0 2 2 2 1 Leucine-rich repeat Rubis-subs-bind PF09273.11 CAM40166.2 - 1.4e-12 48.4 0.0 3.8e-12 47.0 0.0 1.8 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 CAM40166.2 - 0.0058 17.0 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 SET domain NAD_binding_2 PF03446.15 CAM40167.1 - 2.6e-51 173.9 1.0 4.8e-51 173.0 1.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 CAM40167.1 - 2e-36 124.9 0.1 3.4e-36 124.2 0.1 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 CAM40167.1 - 0.00052 19.4 0.0 0.0012 18.2 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 CAM40167.1 - 0.0011 19.5 1.0 0.0046 17.5 0.1 2.5 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 CAM40167.1 - 0.0043 17.0 0.1 0.0094 15.8 0.1 1.7 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 CAM40167.1 - 0.016 15.3 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 CAM40167.1 - 0.019 14.5 0.1 3 7.4 0.0 2.3 1 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PDH PF02153.17 CAM40167.1 - 0.039 13.0 0.0 0.057 12.4 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase IlvN PF07991.12 CAM40167.1 - 0.045 13.3 0.2 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain TetR_C_36 PF18598.1 CAM40169.1 - 0.27 11.2 1.7 2 8.4 0.1 2.8 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Gly-zipper_Omp PF13488.6 CAM40170.1 - 0.27 11.3 7.1 0.45 10.6 7.1 1.4 1 0 0 1 1 1 0 Glycine zipper RrnaAD PF00398.20 CAM40171.1 - 3.1e-61 206.8 0.0 4.1e-61 206.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 CAM40171.1 - 9.4e-08 32.7 0.0 1.7e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAM40171.1 - 2.8e-05 24.7 0.0 5.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAM40171.1 - 0.0013 19.4 0.0 0.0025 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAM40171.1 - 0.0015 18.4 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CAM40171.1 - 0.018 14.8 0.0 0.028 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 CAM40171.1 - 0.034 13.5 0.0 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_31 PF13847.6 CAM40171.1 - 0.041 13.7 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 CAM40171.1 - 0.046 12.8 0.0 0.084 11.9 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_28 PF02636.17 CAM40171.1 - 0.049 13.2 0.0 0.084 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 CAM40171.1 - 0.07 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 CAM40171.1 - 0.085 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 CAM40171.1 - 0.099 12.0 0.0 0.23 10.8 0.0 1.5 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 CAM40171.1 - 0.11 12.4 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain zf-RanBP PF00641.18 CAM40172.1 - 0.0039 16.5 5.9 0.0039 16.5 5.9 1.9 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others Mito_carr PF00153.27 CAM40173.2 - 5.7e-12 45.4 0.2 5.4e-07 29.4 0.0 2.4 2 0 0 2 2 2 2 Mitochondrial carrier protein Tim17 PF02466.19 CAM40173.2 - 0.074 13.4 1.3 0.25 11.8 0.3 2.1 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family RNase_T PF00929.24 CAM40175.1 - 1.4e-16 61.5 0.0 3.2e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 Exonuclease UCH_1 PF13423.6 CAM40175.1 - 9.1e-14 51.8 0.0 4.1e-11 43.1 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 CAM40175.1 - 7e-05 22.4 0.0 0.00018 21.1 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PCuAC PF04314.13 CAM40175.1 - 0.017 14.9 0.0 0.045 13.5 0.0 1.6 1 0 0 1 1 1 0 Copper chaperone PCu(A)C zf-C2H2_4 PF13894.6 CAM40176.1 - 1.9e-15 56.2 52.5 0.013 16.3 0.6 8.4 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2 PF00096.26 CAM40176.1 - 2.9e-11 43.2 49.5 0.0037 17.6 0.2 8.4 8 0 0 8 8 8 4 Zinc finger, C2H2 type zf-Di19 PF05605.12 CAM40176.1 - 3.1e-11 43.4 32.8 0.0013 18.9 2.2 7.1 7 0 0 7 7 7 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 CAM40176.1 - 1.4e-09 38.0 19.3 0.028 14.7 0.1 6.2 6 1 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CAM40176.1 - 2.4e-05 24.6 16.8 0.014 15.7 0.7 5.9 6 0 0 6 6 5 2 Zinc-finger of C2H2 type Actin_micro PF17003.5 CAM40176.1 - 0.00013 21.3 5.3 2.2 7.4 0.2 5.2 5 1 0 5 5 5 1 Putative actin-like family TRAF6_Z2 PF18048.1 CAM40176.1 - 0.0012 18.9 4.9 0.28 11.3 0.1 4.3 4 0 0 4 4 4 1 TNF receptor-associated factor 6 zinc finger 2 zf_C2H2_10 PF18414.1 CAM40176.1 - 0.0019 17.7 10.2 0.022 14.3 0.1 3.9 4 0 0 4 4 4 2 C2H2 type zinc-finger zf-C2HC_2 PF13913.6 CAM40176.1 - 0.0035 17.2 1.2 0.0035 17.2 1.2 4.7 5 0 0 5 5 5 1 zinc-finger of a C2HC-type DUF629 PF04780.12 CAM40176.1 - 0.006 15.2 15.1 5.1 5.5 0.3 5.6 4 1 1 6 6 6 1 Protein of unknown function (DUF629) zf-C2H2_9 PF16293.5 CAM40176.1 - 0.013 15.3 11.7 6.7 6.6 0.3 4.7 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) Zf_RING PF16744.5 CAM40176.1 - 0.016 15.3 6.7 1.2 9.3 0.0 4.2 4 0 0 4 4 4 0 KIAA1045 RING finger zf-C2H2_8 PF15909.5 CAM40176.1 - 0.031 14.6 0.6 0.031 14.6 0.6 4.4 4 1 0 4 4 4 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 CAM40176.1 - 0.045 14.4 25.1 40 4.9 2.6 7.8 6 2 2 8 8 8 0 FOXP coiled-coil domain zf-RING_7 PF02591.15 CAM40176.1 - 0.14 12.3 6.5 9.8 6.5 0.3 4.2 4 0 0 4 4 4 0 C4-type zinc ribbon domain zf-tcix PF14952.6 CAM40176.1 - 0.15 11.7 0.0 0.15 11.7 0.0 2.4 3 0 0 3 3 2 0 Putative treble-clef, zinc-finger, Zn-binding zf-H2C2_2 PF13465.6 CAM40176.1 - 0.17 12.4 0.2 0.17 12.4 0.2 7.5 8 1 0 8 8 7 0 Zinc-finger double domain zf-C2H2_3rep PF18868.1 CAM40176.1 - 0.21 12.3 20.6 2.8 8.6 0.6 5.9 3 1 4 7 7 7 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 CAM40176.1 - 0.28 11.5 25.2 0.75 10.2 0.5 6.6 5 2 1 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 CAM40176.1 - 0.31 11.1 15.2 7.6 6.7 0.3 5.8 6 0 0 6 6 5 0 C2H2-type zinc finger zf_UBZ PF18439.1 CAM40176.1 - 0.43 10.2 20.5 1.3 8.6 2.0 6.2 5 1 1 6 6 6 0 Ubiquitin-Binding Zinc Finger OrfB_Zn_ribbon PF07282.11 CAM40176.1 - 0.46 10.4 2.3 7.8 6.5 0.1 3.4 3 0 0 3 3 3 0 Putative transposase DNA-binding domain IBR PF01485.21 CAM40176.1 - 0.61 10.4 8.3 25 5.2 0.1 3.9 4 0 0 4 4 3 0 IBR domain, a half RING-finger domain zf-TFIIB PF13453.6 CAM40176.1 - 0.78 9.1 11.5 0.81 9.1 0.4 3.9 4 0 0 4 4 3 0 Transcription factor zinc-finger zinc_ribbon_9 PF14369.6 CAM40176.1 - 1.4 9.3 19.0 2.2 8.6 0.3 5.6 5 1 0 5 5 5 0 zinc-ribbon CpXC PF14353.6 CAM40176.1 - 2.8 8.0 11.0 4.8 7.2 0.0 4.7 4 1 1 5 5 5 0 CpXC protein Prok-RING_4 PF14447.6 CAM40176.1 - 3.9 7.4 13.8 15 5.5 1.2 4.8 5 0 0 5 5 5 0 Prokaryotic RING finger family 4 Evr1_Alr PF04777.13 CAM40176.1 - 5.7 7.5 11.4 8.8 6.9 0.1 4.5 3 1 2 5 5 4 0 Erv1 / Alr family Mut7-C PF01927.16 CAM40176.1 - 5.8 7.0 8.1 3.3 7.8 0.4 3.4 3 1 1 4 4 3 0 Mut7-C RNAse domain Rad50_zn_hook PF04423.14 CAM40176.1 - 5.8 6.8 11.0 31 4.5 0.5 4.3 4 0 0 4 4 4 0 Rad50 zinc hook motif GAGA PF09237.11 CAM40176.1 - 5.8 6.8 6.4 13 5.7 0.0 3.7 4 0 0 4 4 4 0 GAGA factor Zn_ribbon_SprT PF17283.2 CAM40176.1 - 7.3 6.6 7.4 18 5.4 0.1 3.7 3 0 0 3 3 3 0 SprT-like zinc ribbon domain zinc_ribbon_5 PF13719.6 CAM40176.1 - 8 6.3 11.9 42 4.0 0.0 4.6 5 0 0 5 5 4 0 zinc-ribbon domain Peptidase_C54 PF03416.19 CAM40177.2 - 5.4e-45 153.9 0.1 1.3e-44 152.7 0.1 1.6 1 1 0 1 1 1 1 Peptidase family C54 COP23 PF14218.6 CAM40177.2 - 0.0053 16.5 0.1 0.011 15.5 0.1 1.5 1 0 0 1 1 1 1 Circadian oscillating protein COP23 Peptidase_C78 PF07910.13 CAM40177.2 - 0.083 12.4 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Peptidase family C78 LIM PF00412.22 CAM40178.1 - 3.8e-05 23.8 12.4 0.00011 22.4 9.7 2.5 2 1 0 2 2 2 1 LIM domain NCD3G PF07562.14 CAM40178.1 - 0.064 13.2 4.9 4.7 7.3 0.1 2.4 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR zf-PARP PF00645.18 CAM40178.1 - 0.26 12.2 3.2 6.9 7.6 2.1 2.4 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Hpt PF01627.23 CAM40179.1 - 0.033 14.4 0.1 0.088 13.1 0.1 1.7 1 0 0 1 1 1 0 Hpt domain ChaB PF06150.12 CAM40181.1 - 0.39 11.3 0.1 0.39 11.3 0.1 3.1 3 0 0 3 3 3 0 ChaB Sad1_UNC PF07738.13 CAM40182.1 - 3.9e-18 65.7 0.0 6.3e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Spc7 PF08317.11 CAM40182.1 - 0.031 13.1 3.3 0.044 12.7 3.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein ATG16 PF08614.11 CAM40182.1 - 0.04 14.2 1.9 0.063 13.5 1.9 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) TACC_C PF05010.14 CAM40182.1 - 0.086 12.6 1.2 0.13 12.1 1.2 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Occludin_ELL PF07303.13 CAM40182.1 - 0.81 10.4 4.8 1.8 9.3 4.9 1.5 1 1 0 1 1 1 0 Occludin homology domain IFT57 PF10498.9 CAM40182.1 - 1.3 7.9 2.9 1.9 7.4 2.9 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Jnk-SapK_ap_N PF09744.9 CAM40182.1 - 8.7 6.5 7.5 14 5.9 7.5 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 FAM104 PF15434.6 CAM40183.1 - 0.13 12.9 1.3 0.34 11.5 0.1 2.1 2 0 0 2 2 2 0 Family 104 Tom22 PF04281.13 CAM40184.1 - 0.1 12.4 0.4 0.26 11.1 0.4 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 NCA2 PF08637.10 CAM40185.1 - 3.9e-37 128.0 0.1 5.6e-28 97.9 0.0 2.2 1 1 0 2 2 2 2 ATP synthase regulation protein NCA2 RabGAP-TBC PF00566.18 CAM40186.1 - 1.3e-07 31.5 0.1 2.2e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF1805 PF08827.11 CAM40186.1 - 0.031 14.6 0.4 0.087 13.2 0.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) FAM104 PF15434.6 CAM40186.1 - 0.14 12.7 1.0 0.48 11.0 0.0 2.2 2 0 0 2 2 2 0 Family 104 Ku PF02735.16 CAM40187.1 - 5.4e-28 98.1 0.0 8.9e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 CAM40187.1 - 1.9e-19 70.0 0.0 4.1e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 Ku C terminal domain like Ku_N PF03731.15 CAM40187.1 - 6.7e-08 32.5 0.0 1.7e-07 31.3 0.0 1.6 1 1 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 CAM40187.1 - 0.00099 19.8 0.1 0.0023 18.6 0.1 1.5 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm VWA PF00092.28 CAM40187.1 - 0.022 15.0 0.0 0.061 13.6 0.0 1.7 1 0 0 1 1 1 0 von Willebrand factor type A domain VWA_2 PF13519.6 CAM40187.1 - 0.13 12.9 0.2 3.5 8.3 0.1 3.2 2 1 0 2 2 2 0 von Willebrand factor type A domain Kinesin PF00225.23 CAM40188.1 - 2.1e-90 303.0 1.4 3.2e-90 302.5 1.4 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CAM40188.1 - 1.7e-26 92.9 0.3 6.5e-26 91.1 0.1 2.1 2 0 0 2 2 2 1 Microtubule binding TSC22 PF01166.18 CAM40188.1 - 0.0014 18.9 0.3 0.0055 17.0 0.3 2.0 1 0 0 1 1 1 1 TSC-22/dip/bun family YabA PF06156.13 CAM40188.1 - 0.0099 16.5 2.4 0.0099 16.5 2.4 2.7 2 1 0 2 2 2 1 Initiation control protein YabA bZIP_1 PF00170.21 CAM40188.1 - 0.016 15.3 0.3 0.016 15.3 0.3 2.4 2 0 0 2 2 2 0 bZIP transcription factor NRBF2 PF08961.10 CAM40188.1 - 0.017 14.7 2.0 0.017 14.7 2.0 1.7 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator PIF1 PF05970.14 CAM40188.1 - 0.023 13.9 0.2 0.05 12.8 0.2 1.5 1 0 0 1 1 1 0 PIF1-like helicase AAA_16 PF13191.6 CAM40188.1 - 0.033 14.6 3.2 0.044 14.2 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 CAM40188.1 - 0.053 13.8 0.7 0.3 11.4 0.2 2.5 2 1 0 2 2 2 0 AAA domain DivIC PF04977.15 CAM40188.1 - 7.5 6.4 14.0 0.73 9.7 0.1 4.0 4 0 0 4 4 4 0 Septum formation initiator EMP70 PF02990.16 CAM40189.1 - 7.4e-150 500.0 10.0 1e-149 499.6 10.0 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Pkinase PF00069.25 CAM40190.2 - 4.4e-59 200.0 0.0 1.5e-58 198.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM40190.2 - 1.4e-25 90.1 0.0 1.9e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM40190.2 - 0.00017 21.0 0.0 0.00048 19.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like DUF3455 PF11937.8 CAM40190.2 - 0.097 13.0 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3455) Seadorna_VP7 PF07387.11 CAM40190.2 - 0.22 10.6 0.0 0.36 9.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 PP2C PF00481.21 CAM40191.1 - 4.5e-49 167.4 0.1 6.3e-49 166.9 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CAM40191.1 - 0.0011 18.9 0.0 0.0056 16.6 0.0 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) SHQ1 PF04925.15 CAM40192.2 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 SHQ1 protein GPS PF01825.21 CAM40192.2 - 0.23 12.0 3.6 3.9 8.1 0.0 2.5 2 0 0 2 2 2 0 GPCR proteolysis site, GPS, motif Cytochrome_CBB3 PF13442.6 CAM40193.1 - 7.5 7.0 8.8 4.9 7.6 0.8 2.5 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III CBFD_NFYB_HMF PF00808.23 CAM40194.1 - 0.0025 18.1 0.3 0.0037 17.5 0.3 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF4803 PF16061.5 CAM40194.1 - 0.014 14.9 0.0 0.017 14.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4803) TAF PF02969.17 CAM40194.1 - 0.014 15.5 0.3 0.021 15.0 0.3 1.2 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) CENP-T_C PF15511.6 CAM40194.1 - 0.063 13.4 0.0 0.082 13.0 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 CAM40194.1 - 0.075 13.1 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated Hydrolase_4 PF12146.8 CAM40196.1 - 1.4e-12 47.4 0.0 9.4e-09 34.9 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CAM40196.1 - 4.6e-09 36.3 0.2 1.7e-05 24.6 0.2 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 CAM40196.1 - 1.3e-07 31.5 0.0 7.3e-07 29.1 0.0 1.9 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 CAM40196.1 - 2.8e-05 23.7 0.1 0.00028 20.4 0.1 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 CAM40196.1 - 0.00028 21.6 0.0 0.00043 21.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 CAM40196.1 - 0.02 13.6 0.0 1.6 7.3 0.0 2.4 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) FSH1 PF03959.13 CAM40196.1 - 0.029 14.0 0.0 0.061 13.0 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Esterase PF00756.20 CAM40196.1 - 0.043 13.5 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative esterase PhoPQ_related PF10142.9 CAM40196.1 - 0.052 12.2 0.0 0.062 11.9 0.0 1.1 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein PAP2 PF01569.21 CAM40197.1 - 6e-21 74.6 2.2 9e-21 74.1 2.2 1.3 1 0 0 1 1 1 1 PAP2 superfamily DUF2252 PF10009.9 CAM40197.1 - 0.1 11.6 0.1 0.57 9.2 0.0 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2252) DUF4149 PF13664.6 CAM40197.1 - 1 9.7 5.8 2.3 8.6 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) WD40 PF00400.32 CAM40198.1 - 2.3e-26 91.5 22.1 4.7e-09 36.7 0.5 7.5 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM40198.1 - 6.2e-15 55.3 0.3 0.00016 21.9 0.0 5.4 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CAM40198.1 - 0.00043 19.3 0.0 0.051 12.5 0.0 2.5 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DAGK_cat PF00781.24 CAM40199.2 - 4.6e-13 48.9 0.0 7e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF348 PF03990.14 CAM40199.2 - 0.013 15.3 0.0 0.15 11.8 0.0 2.5 2 0 0 2 2 2 0 G5-linked-Ubiquitin-like domain Evr1_Alr PF04777.13 CAM40200.1 - 1.6e-15 57.4 0.1 3.8e-15 56.2 0.1 1.7 1 0 0 1 1 1 1 Erv1 / Alr family Thioredoxin PF00085.20 CAM40200.1 - 5.8e-08 32.6 0.0 1.3e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 CAM40200.1 - 0.024 14.0 0.0 0.12 11.8 0.0 2.0 3 0 0 3 3 3 0 OST3 / OST6 family, transporter family DUF3693 PF12472.8 CAM40200.1 - 0.055 13.1 0.3 0.19 11.4 0.2 2.0 2 0 0 2 2 2 0 Phage related protein RRF PF01765.19 CAM40201.1 - 1.5e-14 54.3 3.0 3e-14 53.3 0.7 1.9 1 1 1 2 2 2 1 Ribosome recycling factor IF4E PF01652.18 CAM40202.1 - 1.3e-27 96.6 0.0 1.7e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E PAM2 PF07145.15 CAM40202.1 - 0.069 12.9 0.2 0.069 12.9 0.2 2.2 2 0 0 2 2 2 0 Ataxin-2 C-terminal region tRNA-synt_2 PF00152.20 CAM40203.1 - 4.4e-74 249.4 0.1 6.6e-74 248.8 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CAM40203.1 - 1.4e-08 34.6 0.4 2.4e-08 33.8 0.4 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CAM40203.1 - 0.00028 20.4 0.4 0.92 8.9 0.1 2.6 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Bystin PF05291.11 CAM40205.1 - 5.2e-110 367.3 1.2 7.1e-110 366.9 1.2 1.1 1 0 0 1 1 1 1 Bystin DUF3299 PF11736.8 CAM40205.1 - 0.013 15.5 0.5 0.067 13.2 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3299) GPHR_N PF12537.8 CAM40206.2 - 3.8 7.7 4.5 25 5.0 0.6 2.7 2 0 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal TraG-D_C PF12696.7 CAM40207.1 - 6.2 6.8 5.8 1.1 9.3 1.4 2.0 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG LRR_4 PF12799.7 CAM40208.2 - 6.5e-07 29.6 1.5 0.0014 19.0 0.0 3.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM40208.2 - 0.0036 17.0 2.6 0.0066 16.2 0.5 2.1 2 1 0 2 2 2 1 Leucine rich repeat LRR_9 PF14580.6 CAM40208.2 - 0.0084 15.6 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat NatB_MDM20 PF09797.9 CAM40209.2 - 2.3e-25 89.3 0.0 1.6e-24 86.6 0.0 2.0 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_16 PF13432.6 CAM40209.2 - 0.18 12.4 2.6 1.5 9.5 0.3 3.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 CAM40209.2 - 2.7 9.0 18.6 0.31 12.0 0.3 6.4 7 1 1 8 8 8 0 Tetratricopeptide repeat Alg14 PF08660.11 CAM40210.1 - 2.6e-54 183.8 0.0 3.6e-54 183.3 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Glyco_tran_28_C PF04101.16 CAM40210.1 - 1.7e-18 67.2 0.0 3.9e-18 66.0 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain RRM_1 PF00076.22 CAM40211.1 - 1.4e-16 60.1 0.0 3.1e-16 58.9 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LMBR1 PF04791.16 CAM40212.1 - 5.8e-55 187.2 21.9 8e-55 186.7 21.9 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF3037 PF11236.8 CAM40213.1 - 0.25 11.8 4.5 4.9 7.6 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3037) PSP PF04046.16 CAM40214.1 - 1.3e-18 66.6 3.0 2.8e-18 65.5 3.0 1.6 1 0 0 1 1 1 1 PSP DUF382 PF04037.13 CAM40214.1 - 1.4e-11 44.6 0.0 1.4e-11 44.6 0.0 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF382) LUC7 PF03194.15 CAM40214.1 - 0.63 9.7 12.3 0.88 9.2 12.3 1.2 1 0 0 1 1 1 0 LUC7 N_terminus AMP-binding PF00501.28 CAM40215.1 - 1.2e-24 86.8 0.0 3.1e-11 42.5 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme BBS2_C PF14782.6 CAM40216.2 - 7.2e-132 440.2 0.0 9e-132 439.9 0.0 1.1 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.6 CAM40216.2 - 1.4e-22 79.7 0.0 1.2e-21 76.8 0.0 2.5 2 1 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region FG-GAP PF01839.23 CAM40216.2 - 0.00025 21.1 1.4 0.00048 20.2 0.6 1.9 2 0 0 2 2 2 1 FG-GAP repeat VCBS PF13517.6 CAM40216.2 - 0.005 17.4 0.1 0.012 16.2 0.1 1.7 1 0 0 1 1 1 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella APG6_N PF17675.1 CAM40216.2 - 0.04 14.4 0.2 0.04 14.4 0.2 1.8 2 0 0 2 2 2 0 Apg6 coiled-coil region FlgN PF05130.12 CAM40216.2 - 1.2 9.7 8.8 0.094 13.2 0.6 2.7 2 1 0 2 2 2 0 FlgN protein HALZ PF02183.18 CAM40216.2 - 2.5 8.4 6.3 0.73 10.1 2.7 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper Pkinase PF00069.25 CAM40217.1 - 2.2e-64 217.4 0.0 2.8e-64 217.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM40217.1 - 1.5e-40 139.1 0.0 2.1e-40 138.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM40217.1 - 0.00036 19.9 0.0 0.00068 19.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CAM40217.1 - 0.013 14.3 0.0 0.033 13.0 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase Cyt-b5 PF00173.28 CAM40218.1 - 3.2e-26 91.3 0.0 1.6e-16 60.2 0.0 2.9 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.21 CAM40218.1 - 3.5e-10 40.5 0.0 1.4e-09 38.6 0.0 2.1 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CAM40218.1 - 0.00061 19.9 0.0 0.0023 18.0 0.0 1.9 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 CAM40218.1 - 0.047 14.0 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain RRS1 PF04939.12 CAM40219.1 - 5.5e-42 143.4 4.5 5.5e-42 143.4 4.5 1.6 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) tRNA-synt_His PF13393.6 CAM40220.1 - 1.7e-37 129.4 0.0 2.4e-37 128.9 0.0 1.2 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 CAM40220.1 - 1.2e-06 28.6 0.3 2.8e-06 27.4 0.1 1.7 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CAM40220.1 - 4.4e-05 23.5 0.0 5.3e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF4473 PF14747.6 CAM40220.1 - 0.059 13.9 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) CedA PF10729.9 CAM40222.1 - 0.092 12.6 0.1 0.3 10.9 0.0 1.9 2 0 0 2 2 2 0 Cell division activator CedA DUF1965 PF09248.10 CAM40222.1 - 0.11 12.3 0.1 0.32 10.8 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1965) PDZ_2 PF13180.6 CAM40223.1 - 1.8e-10 41.0 0.0 1.1e-09 38.5 0.0 2.2 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 CAM40223.1 - 2.7e-07 30.3 0.0 7.6e-07 28.9 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PI-PLC-X PF00388.19 CAM40223.1 - 2e-06 27.4 0.0 3.9e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PDZ PF00595.24 CAM40223.1 - 4.2e-05 23.8 0.0 9.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PI-PLC-Y PF00387.19 CAM40223.1 - 0.049 14.0 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 CAM40223.1 - 0.055 14.0 0.1 0.13 12.8 0.1 1.6 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like Ribosomal_S30 PF04758.14 CAM40224.1 - 1.3e-25 89.3 9.1 1.5e-25 89.1 9.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Ribosomal_S30 PF04758.14 CAM40225.1 - 1.3e-25 89.3 9.1 1.5e-25 89.1 9.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Ribosomal_S30 PF04758.14 CAM40226.1 - 4.6e-25 87.6 9.1 5.7e-25 87.3 9.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S30 CS PF04969.16 CAM40227.1 - 3.5e-14 53.6 0.0 5.8e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.17 CAM40229.1 - 5.8e-25 85.4 17.9 0.00087 19.2 0.4 9.1 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_1 PF00515.28 CAM40229.1 - 3.8e-22 77.1 17.2 3.4e-05 23.5 0.4 7.8 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 CAM40229.1 - 2.1e-18 64.9 10.6 0.0001 22.2 0.1 6.9 8 0 0 8 8 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 CAM40229.1 - 2.2e-16 59.9 10.5 7.6e-08 32.5 0.1 6.3 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 CAM40229.1 - 1.1e-14 54.6 3.4 0.00073 20.0 0.1 6.3 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 CAM40229.1 - 4.9e-13 48.1 9.2 0.00088 19.1 0.2 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 CAM40229.1 - 2.2e-12 47.4 6.6 0.0025 18.4 0.0 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 CAM40229.1 - 2.5e-10 40.3 7.3 2.3 9.3 0.0 8.8 7 2 3 10 10 10 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CAM40229.1 - 9.1e-10 38.6 24.5 2e-05 24.7 0.2 4.5 5 1 1 6 6 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 CAM40229.1 - 2.3e-07 30.7 7.3 0.11 12.9 0.0 6.9 7 1 0 7 7 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 CAM40229.1 - 4.7e-07 30.0 10.6 0.0011 19.4 0.8 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 CAM40229.1 - 1.3e-06 28.0 11.0 0.0091 15.7 0.3 5.4 4 2 2 6 6 6 2 TPR repeat TPR_15 PF13429.6 CAM40229.1 - 2e-05 24.0 0.4 0.37 10.0 0.0 4.0 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 CAM40229.1 - 0.00014 22.0 1.3 0.037 14.2 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat SNAP PF14938.6 CAM40229.1 - 0.011 15.2 6.6 0.037 13.4 3.0 3.0 2 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP Sel1 PF08238.12 CAM40229.1 - 0.019 15.7 6.0 23 5.8 0.1 4.8 4 0 0 4 4 4 0 Sel1 repeat Alkyl_sulf_dimr PF14863.6 CAM40229.1 - 0.036 14.5 0.0 22 5.5 0.0 3.4 2 1 1 3 3 3 0 Alkyl sulfatase dimerisation TPR_10 PF13374.6 CAM40229.1 - 0.065 13.1 9.4 2.9 7.9 0.4 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat NARP1 PF12569.8 CAM40229.1 - 0.089 11.7 0.1 0.29 10.0 0.0 1.8 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 BTAD PF03704.17 CAM40229.1 - 0.16 12.4 9.8 3 8.3 0.1 4.5 4 2 1 5 5 5 0 Bacterial transcriptional activator domain DUF3856 PF12968.7 CAM40229.1 - 0.2 11.7 2.6 0.65 10.1 0.2 2.8 3 0 0 3 3 3 0 Domain of Unknown Function (DUF3856) Fis1_TPR_C PF14853.6 CAM40229.1 - 0.3 11.2 14.5 7.2 6.8 0.1 5.2 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat GrpE PF01025.19 CAM40231.1 - 3.4e-41 140.7 3.7 4.1e-41 140.4 3.7 1.1 1 0 0 1 1 1 1 GrpE Bcr-Abl_Oligo PF09036.10 CAM40231.1 - 0.13 12.2 0.1 0.27 11.2 0.1 1.5 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain GrpE PF01025.19 CAM40232.1 - 1.1e-37 129.2 2.2 1.4e-37 128.9 2.2 1.1 1 0 0 1 1 1 1 GrpE Neugrin PF06413.11 CAM40232.1 - 0.057 13.4 0.2 0.094 12.7 0.2 1.4 1 1 0 1 1 1 0 Neugrin Herpes_US9 PF06072.11 CAM40232.1 - 0.1 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 YabA PF06156.13 CAM40232.1 - 0.4 11.3 3.5 1 10.0 2.0 2.1 1 1 1 2 2 2 0 Initiation control protein YabA Sulfate_transp PF00916.20 CAM40234.1 - 9.1e-46 156.3 19.6 1.3e-45 155.8 19.6 1.3 1 0 0 1 1 1 1 Sulfate permease family His_Phos_2 PF00328.22 CAM40234.1 - 7.4e-15 55.2 0.0 6.1e-14 52.2 0.0 2.1 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) STAS PF01740.21 CAM40234.1 - 6.6e-08 32.2 0.0 1.3e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain DJ-1_PfpI PF01965.24 CAM40236.1 - 1.6e-30 106.1 0.1 2e-30 105.8 0.1 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 CAM40236.1 - 0.048 13.4 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 ThiJ/PfpI family-like Arm PF00514.23 CAM40237.1 - 6.1e-19 67.4 19.7 0.16 12.1 0.0 11.8 12 0 0 12 12 12 5 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 CAM40237.1 - 2.5e-18 65.9 13.4 0.0054 16.7 0.0 8.6 2 2 6 9 9 9 6 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.6 CAM40237.1 - 1e-06 29.0 7.2 0.02 15.3 0.6 5.4 4 1 1 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 CAM40237.1 - 4.4e-05 23.9 11.9 0.17 12.4 0.5 6.2 5 2 1 6 6 6 2 HEAT-like repeat DOG1 PF14144.6 CAM40237.1 - 0.0073 16.5 7.5 0.32 11.3 0.0 4.9 4 1 1 5 5 5 1 Seed dormancy control FliG_N PF14842.6 CAM40237.1 - 0.065 13.8 2.0 4.1 8.0 0.1 3.9 4 0 0 4 4 4 0 FliG N-terminal domain DUF3349 PF11829.8 CAM40237.1 - 0.16 12.8 2.7 31 5.4 0.0 4.5 5 0 0 5 5 5 0 Protein of unknown function (DUF3349) UME PF08064.13 CAM40237.1 - 0.36 10.8 5.4 1.4 8.8 0.1 4.1 3 1 0 3 3 3 0 UME (NUC010) domain ESCRT-II PF05871.12 CAM40237.1 - 5.2 7.3 4.9 53 4.1 0.0 4.0 3 1 0 4 4 4 0 ESCRT-II complex subunit RIIa PF02197.17 CAM40238.1 - 0.024 14.3 0.1 0.067 12.9 0.0 1.8 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit Pkinase PF00069.25 CAM40241.1 - 1.2e-70 238.0 0.1 3.4e-70 236.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM40241.1 - 4.6e-32 111.3 0.0 7.9e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 CAM40241.1 - 8e-06 26.3 0.2 2.5e-05 24.7 0.1 1.9 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.6 CAM40241.1 - 4.9e-05 22.8 0.0 0.00011 21.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 CAM40241.1 - 0.02 14.2 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CAM40241.1 - 0.045 13.7 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family GH97_C PF14509.6 CAM40241.1 - 0.095 12.9 0.0 0.49 10.7 0.0 2.2 2 0 0 2 2 2 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation FlaG PF03646.15 CAM40242.1 - 0.11 12.7 0.1 0.18 12.0 0.1 1.3 1 0 0 1 1 1 0 FlaG protein DUF3383 PF11863.8 CAM40242.1 - 0.37 9.8 3.3 0.49 9.4 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3383) Methyltransf_PK PF05891.12 CAM40243.1 - 2.3e-66 223.5 0.0 2.8e-66 223.2 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 CAM40243.1 - 3.6e-12 46.8 0.0 6e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAM40243.1 - 7.8e-12 45.7 0.0 1.2e-11 45.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAM40243.1 - 8.2e-07 29.0 0.0 1.3e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAM40243.1 - 4.4e-06 27.3 0.0 7.8e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAM40243.1 - 4.5e-06 26.5 0.0 1.8e-05 24.6 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 CAM40243.1 - 4.1e-05 23.0 0.0 5.8e-05 22.5 0.0 1.3 1 1 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 CAM40243.1 - 7.8e-05 22.3 0.0 0.00013 21.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain Bin3 PF06859.12 CAM40243.1 - 0.16 12.6 0.0 0.3 11.8 0.0 1.4 1 0 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) Fib_alpha PF08702.10 CAM40244.1 - 7 6.8 9.2 3.7 7.7 2.3 3.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Prefoldin_2 PF01920.20 CAM40245.1 - 9.2e-08 32.0 2.2 9.2e-08 32.0 2.2 1.7 1 1 0 1 1 1 1 Prefoldin subunit DUF722 PF05263.11 CAM40245.1 - 0.11 12.7 1.0 0.24 11.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF722) Med30 PF11315.8 CAM40245.1 - 0.12 12.6 5.4 0.52 10.5 5.4 1.8 1 1 0 1 1 1 0 Mediator complex subunit 30 UPF0242 PF06785.11 CAM40245.1 - 0.16 12.1 4.0 0.21 11.7 4.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 CAM40245.1 - 0.84 9.1 6.0 0.23 11.0 1.5 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit GAS PF13851.6 CAM40245.1 - 0.99 8.7 9.8 0.058 12.7 1.0 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding MMR_HSR1 PF01926.23 CAM40246.1 - 4.9e-07 29.8 0.0 0.00015 21.8 0.0 3.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 CAM40246.1 - 9.6e-06 25.5 0.0 0.00055 19.8 0.0 2.9 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 CAM40246.1 - 4.2e-05 23.7 0.0 0.0011 19.0 0.0 2.4 2 1 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.27 CAM40246.1 - 0.0002 21.0 0.0 0.00042 19.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CAM40246.1 - 0.00043 19.8 0.1 0.27 10.7 0.0 2.7 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CAM40246.1 - 0.0098 15.8 0.0 0.33 10.8 0.0 3.0 2 1 0 2 2 2 1 RsgA GTPase Amastin PF07344.11 CAM40247.1 - 1.5e-44 151.5 8.9 1.8e-44 151.3 8.9 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein PP2C PF00481.21 CAM40248.1 - 1.9e-11 44.1 0.0 2.1e-11 43.9 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C Amastin PF07344.11 CAM40249.1 - 8.3e-39 132.9 4.1 1e-38 132.6 4.1 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein zf-LITAF-like PF10601.9 CAM40249.1 - 0.37 11.1 2.5 17 5.8 0.0 3.2 2 1 2 4 4 4 0 LITAF-like zinc ribbon domain PfkB PF00294.24 CAM40250.1 - 2.2e-56 191.4 0.1 3e-56 191.0 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DAGK_cat PF00781.24 CAM40250.1 - 0.027 14.1 0.0 0.066 12.8 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain HECT PF00632.25 CAM40252.1 - 2.9e-76 256.9 0.0 4e-76 256.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF2164 PF09932.9 CAM40253.1 - 0.035 14.2 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2164) DUF4139 PF13598.6 CAM40254.1 - 4e-45 154.1 0.0 6.4e-45 153.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 CAM40254.1 - 2.6e-05 24.6 5.5 0.00063 20.1 1.4 2.6 2 0 0 2 2 2 2 N-terminal domain of unknown function (DUF4140) ADIP PF11559.8 CAM40254.1 - 0.02 15.0 2.0 0.9 9.6 0.2 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding GP41 PF00517.17 CAM40254.1 - 0.058 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Retroviral envelope protein GCP_C_terminal PF04130.13 CAM40255.1 - 4.5e-22 78.9 0.1 8.9e-22 77.9 0.1 1.5 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 CAM40255.1 - 4.3e-05 23.3 0.0 0.00035 20.3 0.0 2.1 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal RWP-RK PF02042.15 CAM40255.1 - 0.0085 16.1 0.0 0.032 14.2 0.0 2.0 1 0 0 1 1 1 1 RWP-RK domain WD40 PF00400.32 CAM40256.1 - 5.5e-13 49.2 12.4 0.00037 21.2 0.7 5.8 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 CAM40256.1 - 2.5e-10 40.5 0.0 7.1e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 CAM40256.1 - 0.0001 22.5 0.1 0.31 11.4 0.0 3.4 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain MAM33 PF02330.16 CAM40258.1 - 7.6e-31 107.7 1.6 5.3e-26 91.9 1.4 2.1 1 1 1 2 2 2 2 Mitochondrial glycoprotein ABM PF03992.16 CAM40258.1 - 0.015 15.4 0.1 0.2 11.8 0.0 2.4 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase APG5 PF04106.12 CAM40259.1 - 0.018 14.7 0.0 0.072 12.7 0.0 2.0 1 1 0 1 1 1 0 Autophagy protein Apg5 Pkinase PF00069.25 CAM40261.1 - 1.6e-36 126.1 0.0 1.9e-15 57.0 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CAM40261.1 - 9.8e-23 80.7 0.0 9.2e-14 51.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Ufd2P_core PF10408.9 CAM40262.1 - 2.5e-97 327.0 0.6 3.2e-97 326.7 0.6 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core Thioredoxin PF00085.20 CAM40262.1 - 5.5e-22 77.7 0.0 1.2e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CAM40262.1 - 8e-07 29.5 1.3 3.7e-06 27.4 0.3 2.4 2 0 0 2 2 2 1 Thioredoxin-like domain OST3_OST6 PF04756.13 CAM40262.1 - 1e-06 28.4 0.0 1.7e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 CAM40262.1 - 0.00024 21.3 0.1 0.062 13.6 0.1 2.8 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 CAM40262.1 - 0.00075 19.3 0.0 0.0022 17.8 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 CAM40262.1 - 0.0043 17.2 0.2 0.019 15.1 0.2 2.1 2 0 0 2 2 2 1 Thioredoxin-like U-box PF04564.15 CAM40262.1 - 0.009 16.2 0.0 0.064 13.4 0.0 2.5 2 0 0 2 2 2 1 U-box domain AhpC-TSA PF00578.21 CAM40262.1 - 0.025 14.5 0.1 0.07 13.1 0.1 1.8 1 0 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.10 CAM40262.1 - 0.091 12.5 0.1 1.1 9.0 0.1 2.2 1 1 1 2 2 2 0 Redoxin DnaJ PF00226.31 CAM40264.1 - 0.0013 18.8 0.0 0.0031 17.6 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Ribosomal_60s PF00428.19 CAM40264.1 - 0.66 10.6 0.0 0.66 10.6 0.0 2.8 3 1 0 3 3 3 0 60s Acidic ribosomal protein DUF4680 PF15730.5 CAM40264.1 - 3.8 7.8 11.4 0.6 10.5 5.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4680) zf-CCHC_2 PF13696.6 CAM40265.1 - 2 8.3 4.2 1.4 8.8 1.4 2.2 2 0 0 2 2 2 0 Zinc knuckle Mito_carr PF00153.27 CAM40266.1 - 9.4e-47 156.9 2.2 6.3e-17 61.3 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein RF-1 PF00472.20 CAM40267.2 - 8.5e-15 54.7 0.0 1.2e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.9 CAM40267.2 - 0.009 16.4 0.0 0.013 15.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein TRF PF08558.10 CAM40267.2 - 0.16 11.5 0.0 0.22 11.1 0.0 1.1 1 0 0 1 1 1 0 Telomere repeat binding factor (TRF) Sdh5 PF03937.16 CAM40268.1 - 6.4e-19 67.7 0.8 1.2e-18 66.9 0.8 1.5 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase WW PF00397.26 CAM40270.1 - 8.2e-10 38.6 1.8 1.6e-09 37.7 1.8 1.5 1 0 0 1 1 1 1 WW domain ATG16 PF08614.11 CAM40270.1 - 0.013 15.8 0.8 0.013 15.8 0.8 3.3 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Nup54 PF13874.6 CAM40270.1 - 0.14 12.2 2.7 8.1 6.6 0.0 2.9 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DivIVA PF05103.13 CAM40270.1 - 0.49 10.5 5.6 4.5 7.4 0.0 2.5 2 0 0 2 2 2 0 DivIVA protein Peptidase_M3_N PF08439.10 CAM40270.1 - 2.5 8.4 4.8 8.6 6.7 0.1 2.8 2 0 0 2 2 2 0 Oligopeptidase F DREV PF05219.12 CAM40271.1 - 1.8e-61 207.6 0.0 2.1e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_12 PF08242.12 CAM40271.1 - 1.6e-11 44.8 0.0 2.8e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAM40271.1 - 9e-11 42.3 0.0 1.7e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAM40271.1 - 1.9e-10 40.8 0.0 2.6e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAM40271.1 - 1.9e-07 31.7 0.0 3.7e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAM40271.1 - 4.2e-05 23.4 0.0 0.00038 20.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 CAM40271.1 - 0.038 13.5 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain RRM_1 PF00076.22 CAM40272.1 - 3.2e-21 74.9 0.0 2e-09 37.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 CAM40272.1 - 0.00094 19.2 0.0 0.11 12.5 0.0 2.9 3 0 0 3 3 3 1 RNA binding domain DUF4523 PF15023.6 CAM40272.1 - 0.0079 16.0 0.0 0.032 14.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4523) Nup35_RRM_2 PF14605.6 CAM40272.1 - 0.0087 16.0 0.0 5.6 7.1 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Arm PF00514.23 CAM40273.1 - 8.3e-69 225.7 20.1 4.2e-10 39.3 0.0 8.8 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 CAM40273.1 - 4.8e-15 54.9 0.0 1.6e-14 53.2 0.1 1.8 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_2 PF13646.6 CAM40273.1 - 1.2e-13 51.3 3.3 0.0014 19.0 0.1 5.7 3 1 3 6 6 6 5 HEAT repeats HEAT_EZ PF13513.6 CAM40273.1 - 1.6e-12 47.6 12.1 0.00015 22.2 0.2 6.7 5 2 3 8 8 8 3 HEAT-like repeat HEAT PF02985.22 CAM40273.1 - 1.2e-10 40.7 10.6 0.084 13.2 0.0 8.1 9 0 0 9 9 9 4 HEAT repeat Arm_2 PF04826.13 CAM40273.1 - 0.0057 16.2 0.0 0.3 10.5 0.0 3.2 3 1 0 3 3 3 1 Armadillo-like DCB PF16213.5 CAM40273.1 - 0.028 14.1 0.0 0.06 13.0 0.0 1.5 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 Proteasom_PSMB PF10508.9 CAM40273.1 - 0.2 10.1 0.0 0.35 9.3 0.0 1.4 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit MA3 PF02847.17 CAM40276.1 - 7.5e-08 32.4 0.1 1.7e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 MA3 domain DNA_pol3_gamma3 PF12169.8 CAM40276.1 - 0.17 11.8 3.7 0.73 9.7 0.0 3.4 4 0 0 4 4 4 0 DNA polymerase III subunits gamma and tau domain III DHHC PF01529.20 CAM40278.1 - 2.1e-32 112.0 11.3 2.1e-32 112.0 11.3 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase UCH PF00443.29 CAM40281.1 - 1.3e-34 119.9 0.0 2.2e-34 119.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CAM40281.1 - 7.8e-08 32.3 2.3 0.00042 20.0 2.4 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CAM40281.1 - 0.051 13.9 10.1 0.062 13.6 1.1 4.2 3 0 0 3 3 3 0 Zn-finger in ubiquitin-hydrolases and other protein LSM PF01423.22 CAM40282.2 - 1.8e-15 56.3 0.2 2.1e-15 56.1 0.2 1.1 1 0 0 1 1 1 1 LSM domain AAA_28 PF13521.6 CAM40283.1 - 4.8e-19 69.2 0.0 1e-18 68.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 CAM40283.1 - 0.016 14.2 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 CAM40283.1 - 0.07 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 CAM40283.1 - 0.08 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 CAM40283.1 - 0.17 11.6 0.0 0.4 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-C3HC4_3 PF13920.6 CAM40284.1 - 3.7e-08 33.1 13.3 3.7e-08 33.1 13.3 3.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CAM40284.1 - 0.00019 21.2 14.1 0.00019 21.2 14.1 3.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) EF-hand_7 PF13499.6 CAM40285.1 - 3.8e-06 27.3 1.3 0.0022 18.4 0.1 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CAM40285.1 - 0.0018 18.1 0.1 0.007 16.2 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 CAM40285.1 - 0.016 14.7 0.2 0.033 13.7 0.2 1.6 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.32 CAM40285.1 - 0.035 13.7 0.0 0.091 12.4 0.0 1.8 1 0 0 1 1 1 0 EF hand Phos_pyr_kin PF08543.12 CAM40286.1 - 1.2e-16 60.8 0.0 1.7e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 CAM40286.1 - 8e-08 31.9 2.2 8.9e-07 28.5 0.0 2.3 3 0 0 3 3 3 1 pfkB family carbohydrate kinase DUF2922 PF11148.8 CAM40286.1 - 0.17 11.6 0.0 0.37 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) Acetyltransf_7 PF13508.7 CAM40287.1 - 2.4e-05 24.7 0.0 0.00076 19.9 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CAM40287.1 - 0.00021 21.5 0.0 0.00058 20.1 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CAM40287.1 - 0.0014 18.6 0.0 0.02 14.8 0.0 2.6 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CAM40287.1 - 0.0026 17.7 0.1 0.043 13.8 0.0 2.2 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.7 CAM40287.1 - 0.012 15.7 0.0 0.049 13.7 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 CAM40287.1 - 0.12 12.4 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase DUF5631 PF18645.1 CAM40288.2 - 0.2 12.1 2.4 29 5.1 0.0 3.9 4 0 0 4 4 4 0 Family of unknown function (DUF5631) HAUS-augmin3 PF14932.6 CAM40289.1 - 0.0051 16.4 2.0 0.0051 16.4 2.0 3.3 3 1 1 4 4 4 1 HAUS augmin-like complex subunit 3 CENP-F_leu_zip PF10473.9 CAM40289.1 - 0.015 15.4 0.3 0.015 15.4 0.3 2.9 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.22 CAM40289.1 - 0.12 12.6 0.2 0.12 12.6 0.2 3.4 4 1 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Takusan PF04822.13 CAM40289.1 - 0.12 12.2 0.2 0.12 12.2 0.2 2.4 2 0 0 2 2 2 0 Takusan AAA_23 PF13476.6 CAM40289.1 - 0.18 12.3 8.5 10 6.6 8.3 2.2 1 1 0 1 1 1 0 AAA domain GIT_CC PF16559.5 CAM40289.1 - 0.44 10.5 8.8 0.14 12.1 1.6 3.2 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Fib_alpha PF08702.10 CAM40289.1 - 1.3 9.2 4.8 9.1 6.5 0.3 3.5 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Clathrin PF00637.20 CAM40290.2 - 7.7e-09 35.6 0.1 1.5e-07 31.4 0.5 2.3 2 0 0 2 2 2 1 Region in Clathrin and VPS LysM PF01476.20 CAM40290.2 - 0.0083 16.2 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 LysM domain Zn_ribbon_17 PF17120.5 CAM40290.2 - 0.009 15.6 1.7 0.009 15.6 1.7 2.9 3 0 0 3 3 3 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 CAM40290.2 - 0.014 15.3 4.5 0.04 13.8 4.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CAM40290.2 - 0.019 15.3 2.5 0.053 13.8 2.5 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CAM40290.2 - 0.043 14.1 5.2 0.15 12.4 5.2 2.1 1 0 0 1 1 1 0 Ring finger domain zf-ANAPC11 PF12861.7 CAM40290.2 - 0.054 13.5 0.9 0.21 11.7 0.9 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 CAM40290.2 - 0.14 12.0 4.0 0.37 10.7 4.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_4 PF07721.14 CAM40290.2 - 0.53 11.1 3.0 15 6.6 0.8 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-RING_5 PF14634.6 CAM40290.2 - 1.4 9.0 8.5 0.24 11.4 3.8 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3H2C3 PF17122.5 CAM40290.2 - 2.2 8.4 7.3 5.5 7.1 7.3 1.7 1 0 0 1 1 1 0 Zinc-finger Brix PF04427.18 CAM40291.1 - 4.9e-29 101.8 0.2 6.8e-29 101.4 0.2 1.2 1 0 0 1 1 1 1 Brix domain SNF2_N PF00176.23 CAM40292.1 - 3.9e-46 157.4 0.0 6.7e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CAM40292.1 - 1.8e-10 41.2 0.0 3.1e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAM40292.1 - 7e-05 22.9 0.0 0.00017 21.6 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CAM40292.1 - 0.022 14.0 0.0 0.041 13.1 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase ABC_tran PF00005.27 CAM40294.1 - 1.1e-18 68.1 1.1 6.4e-13 49.4 0.7 3.1 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CAM40294.1 - 4.7e-10 39.7 1.0 8.7e-06 25.8 0.1 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CAM40294.1 - 4.2e-05 23.1 1.4 0.24 10.8 0.1 3.1 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CAM40294.1 - 0.00061 20.2 0.0 0.01 16.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 CAM40294.1 - 0.0012 18.5 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 CAM40294.1 - 0.0026 18.3 0.0 0.028 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CAM40294.1 - 0.0046 16.9 0.0 0.013 15.4 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase IstB_IS21 PF01695.17 CAM40294.1 - 0.026 14.3 0.6 5.8 6.6 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein Dynamin_N PF00350.23 CAM40294.1 - 0.027 14.5 0.1 0.049 13.7 0.1 1.4 1 0 0 1 1 1 0 Dynamin family AAA_15 PF13175.6 CAM40294.1 - 0.061 13.0 0.1 0.096 12.4 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 CAM40294.1 - 0.072 12.8 0.0 0.29 10.8 0.0 2.0 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 CAM40294.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.6 CAM40294.1 - 0.15 12.3 0.8 0.48 10.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 CAM40294.1 - 0.19 10.9 0.0 0.27 10.4 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit RabGAP-TBC PF00566.18 CAM40296.1 - 1.4e-35 122.9 1.0 1.8e-35 122.6 0.2 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain RIO1 PF01163.22 CAM40297.1 - 3.5e-45 153.9 0.0 9.1e-45 152.6 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Rio2_N PF09202.11 CAM40297.1 - 4.3e-33 113.4 0.2 1.2e-31 108.7 0.3 2.4 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.23 CAM40297.1 - 9.8e-10 38.8 0.0 1.7e-05 24.9 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CAM40297.1 - 0.00088 18.7 2.5 0.014 14.8 0.0 3.1 4 1 0 4 4 4 1 Lipopolysaccharide kinase (Kdo/WaaP) family PSP1 PF04468.12 CAM40298.1 - 1.2e-13 51.1 0.2 1.9e-13 50.5 0.2 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region PLAC8 PF04749.17 CAM40299.1 - 2.4e-15 57.3 12.2 3.3e-15 56.9 12.2 1.2 1 0 0 1 1 1 1 PLAC8 family DUF1360 PF07098.11 CAM40299.1 - 3.6 7.6 7.1 0.11 12.5 0.8 1.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1360) WD40 PF00400.32 CAM40300.1 - 1.3e-18 67.0 2.9 0.0006 20.6 0.2 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.8 CAM40300.1 - 0.0011 17.7 0.2 1 7.9 0.0 2.5 2 1 1 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CAM40300.1 - 0.011 16.0 0.1 3.1 8.2 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PLAC8 PF04749.17 CAM40301.1 - 2.8e-13 50.7 24.5 3.6e-13 50.3 24.5 1.2 1 0 0 1 1 1 1 PLAC8 family PLAC8 PF04749.17 CAM40302.1 - 4.7e-14 53.2 25.6 6.1e-14 52.8 25.6 1.1 1 0 0 1 1 1 1 PLAC8 family Kinesin PF00225.23 CAM40304.1 - 7e-83 278.3 0.2 7e-83 278.3 0.2 1.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CAM40304.1 - 2.8e-17 63.1 0.8 5.6e-17 62.0 0.1 1.9 2 0 0 2 2 2 1 Microtubule binding AAA_16 PF13191.6 CAM40304.1 - 0.014 15.8 3.5 0.13 12.6 0.0 3.2 3 0 0 3 3 3 0 AAA ATPase domain Serine_protease PF18405.1 CAM40304.1 - 0.13 11.4 0.2 0.25 10.5 0.2 1.4 1 0 0 1 1 1 0 Gammaproteobacterial serine protease S1-P1_nuclease PF02265.16 CAM40305.1 - 8.6e-62 209.2 0.0 1e-61 209.0 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease PseudoU_synth_2 PF00849.22 CAM40306.1 - 2.3e-32 112.3 0.0 8.7e-32 110.4 0.0 1.8 1 1 0 1 1 1 1 RNA pseudouridylate synthase DUF2109 PF09882.9 CAM40306.1 - 0.017 15.1 0.0 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2109) Rad17 PF03215.15 CAM40307.2 - 9.6e-05 22.4 0.0 0.00015 21.7 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 CAM40307.2 - 0.029 14.8 0.6 0.12 12.7 0.2 2.4 1 1 1 2 2 2 0 AAA ATPase domain RuvB_N PF05496.12 CAM40307.2 - 0.046 13.5 0.0 0.082 12.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 CAM40307.2 - 0.057 13.9 0.0 0.33 11.4 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Flavoprotein PF02441.19 CAM40308.1 - 1.2e-46 158.4 4.6 4.6e-44 150.0 0.2 3.0 3 0 0 3 3 3 2 Flavoprotein PseudoU_synth_1 PF01416.20 CAM40310.1 - 3.6e-25 88.5 0.0 5e-24 84.9 0.0 2.3 2 0 0 2 2 2 1 tRNA pseudouridine synthase Pkinase PF00069.25 CAM40311.1 - 4.7e-34 117.9 0.0 9.2e-12 44.9 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CAM40311.1 - 1.2e-15 57.5 0.0 1.5e-06 27.7 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 CAM40311.1 - 0.019 14.3 0.1 0.034 13.5 0.1 1.3 1 0 0 1 1 1 0 Kinase-like DUF1796 PF08795.10 CAM40312.1 - 4.2e-69 231.8 0.0 5.8e-69 231.3 0.0 1.2 1 0 0 1 1 1 1 Putative papain-like cysteine peptidase (DUF1796) PH PF00169.29 CAM40313.2 - 2.2e-06 28.1 4.1 0.003 18.0 0.4 2.7 2 1 0 2 2 2 2 PH domain Actin PF00022.19 CAM40315.1 - 0.0053 15.4 0.0 0.014 14.0 0.0 1.6 2 0 0 2 2 2 1 Actin Ferric_reduct PF01794.19 CAM40316.1 - 1.5e-15 57.4 10.3 1.5e-15 57.4 10.3 2.9 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CAM40316.1 - 5.6e-12 46.1 0.0 2.4e-06 27.7 0.0 2.5 2 1 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CAM40316.1 - 1.2e-08 35.0 0.0 2.6e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 CAM40316.1 - 0.005 17.5 0.0 0.61 10.7 0.0 2.9 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CAM40316.1 - 0.0099 16.2 0.0 0.025 14.9 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain DUF1077 PF06417.12 CAM40319.1 - 5.3e-36 123.2 0.9 6.4e-36 122.9 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) UbiA PF01040.18 CAM40319.1 - 0.0025 17.2 1.0 0.0034 16.7 1.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF4064 PF13273.6 CAM40319.1 - 0.0097 16.2 0.5 0.015 15.6 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) PqiA PF04403.13 CAM40319.1 - 0.014 15.3 1.9 0.018 14.9 1.9 1.1 1 0 0 1 1 1 0 Paraquat-inducible protein A DUF1189 PF06691.11 CAM40319.1 - 0.069 12.7 0.0 8.2 5.9 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1189) DUF5463 PF17551.2 CAM40319.1 - 4.9 7.2 5.9 0.73 9.8 1.4 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5463) HSP33 PF01430.19 CAM40320.1 - 9.3e-12 44.9 0.4 3.6e-05 23.3 0.1 2.9 3 0 0 3 3 3 2 Hsp33 protein AAA_2 PF07724.14 CAM40323.2 - 1.1e-07 32.1 0.0 1.8e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CAM40323.2 - 9.6e-06 25.9 0.0 7.2e-05 23.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CAM40323.2 - 3.3e-05 23.9 0.0 0.0001 22.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF2721 PF11026.8 CAM40323.2 - 0.00021 21.2 4.2 0.00061 19.7 4.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) AAA PF00004.29 CAM40323.2 - 0.0041 17.6 0.0 0.0089 16.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CAM40323.2 - 0.024 15.0 0.1 1.5 9.1 0.0 3.1 2 1 0 2 2 2 0 AAA ATPase domain NPR1_like_C PF12313.8 CAM40323.2 - 0.097 12.2 1.6 1.4 8.5 0.2 2.2 2 0 0 2 2 2 0 NPR1/NIM1 like defence protein C terminal AAA_33 PF13671.6 CAM40323.2 - 0.12 12.6 0.0 0.27 11.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain Ras PF00071.22 CAM40324.1 - 1.3e-39 135.4 0.0 1.9e-39 134.8 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAM40324.1 - 2e-26 92.6 0.0 3e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAM40324.1 - 2.4e-12 46.6 0.0 3.4e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CAM40324.1 - 0.0002 21.4 0.0 0.00032 20.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CAM40324.1 - 0.00026 21.0 0.2 0.086 12.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 CAM40324.1 - 0.0011 18.5 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B Gtr1_RagA PF04670.12 CAM40324.1 - 0.0014 18.0 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 CAM40324.1 - 0.0029 16.8 0.1 0.53 9.4 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit AAA_16 PF13191.6 CAM40324.1 - 0.014 15.8 0.0 0.027 14.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 CAM40324.1 - 0.064 13.0 0.0 0.23 11.2 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATG16 PF08614.11 CAM40326.2 - 0.0021 18.3 25.1 0.0097 16.2 6.7 2.6 2 1 1 3 3 3 2 Autophagy protein 16 (ATG16) Enkurin PF13864.6 CAM40326.2 - 0.021 15.3 5.4 0.021 15.3 5.4 2.5 2 1 0 2 2 2 0 Calmodulin-binding APG6_N PF17675.1 CAM40326.2 - 0.024 15.1 26.7 0.23 12.0 13.6 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region BBS2_C PF14782.6 CAM40326.2 - 0.26 10.0 13.3 0.014 14.2 4.4 2.0 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal DUF4407 PF14362.6 CAM40326.2 - 1.7 7.9 16.1 0.96 8.7 8.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Spc24 PF08286.11 CAM40326.2 - 6.3 7.1 14.3 6.1 7.1 5.1 2.4 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 CLASP_N PF12348.8 CAM40329.1 - 1.2e-11 44.6 0.1 4.1e-07 29.8 0.0 3.6 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.22 CAM40329.1 - 0.0024 18.0 6.3 3 8.4 0.1 6.4 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.6 CAM40329.1 - 0.0061 16.9 8.9 0.11 12.9 0.0 5.1 5 0 0 5 5 5 1 HEAT repeats Cnd1 PF12717.7 CAM40329.1 - 0.02 15.0 1.3 1.7 8.7 0.0 3.3 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 NUC173 PF08161.12 CAM40329.1 - 0.097 12.3 0.4 0.62 9.7 0.1 2.7 3 0 0 3 3 3 0 NUC173 domain DUF3384 PF11864.8 CAM40329.1 - 0.57 9.0 2.9 5.3 5.8 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3384) CoA_trans PF01144.23 CAM40330.1 - 7.7e-32 110.4 0.1 8.8e-32 110.3 0.1 1.0 1 0 0 1 1 1 1 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 CAM40330.1 - 0.0017 18.3 0.0 0.0022 17.9 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain SRCR_2 PF15494.6 CAM40332.1 - 0.047 14.2 0.2 0.06 13.9 0.2 1.3 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain MCR PF18509.1 CAM40332.1 - 0.067 12.8 0.9 0.46 10.1 0.1 2.3 2 0 0 2 2 2 0 Magnetochrome domain AAA_18 PF13238.6 CAM40333.1 - 1.4e-28 100.1 0.0 1.9e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CAM40333.1 - 4.4e-08 33.4 0.1 1.3e-05 25.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CAM40333.1 - 5e-08 33.5 1.4 9e-08 32.6 0.3 2.0 2 1 0 2 2 1 1 AAA domain AAA PF00004.29 CAM40333.1 - 1.6e-05 25.3 0.3 2.7e-05 24.6 0.3 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CAM40333.1 - 1.6e-05 25.2 2.2 7.9e-05 23.0 2.0 2.2 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 CAM40333.1 - 0.00015 21.7 0.9 0.51 10.2 0.1 2.3 1 1 0 2 2 2 2 Deoxynucleoside kinase RuvB_N PF05496.12 CAM40333.1 - 0.00019 21.2 0.0 0.00032 20.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain SKI PF01202.22 CAM40333.1 - 0.00046 20.3 3.9 0.01 15.9 3.9 2.2 1 1 0 1 1 1 1 Shikimate kinase AAA_22 PF13401.6 CAM40333.1 - 0.0013 19.0 0.0 0.0038 17.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CAM40333.1 - 0.0018 18.7 0.0 0.0021 18.5 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 CAM40333.1 - 0.0025 18.2 0.0 0.0053 17.1 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_5 PF07728.14 CAM40333.1 - 0.0036 17.3 0.3 0.0084 16.1 0.1 1.8 1 1 0 2 2 2 1 AAA domain (dynein-related subfamily) ADK PF00406.22 CAM40333.1 - 0.005 17.0 0.2 0.34 11.0 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase AAA_24 PF13479.6 CAM40333.1 - 0.0052 16.5 0.4 0.027 14.2 0.1 2.1 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CAM40333.1 - 0.0059 16.0 0.2 0.027 13.9 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 CAM40333.1 - 0.0074 15.7 0.1 0.018 14.4 0.1 1.6 1 0 0 1 1 1 1 KaiC DUF2075 PF09848.9 CAM40333.1 - 0.0081 15.4 0.1 0.012 14.9 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Cytidylate_kin PF02224.18 CAM40333.1 - 0.0099 15.6 1.8 0.56 9.9 0.0 2.1 1 1 1 2 2 2 1 Cytidylate kinase TIP49 PF06068.13 CAM40333.1 - 0.013 14.7 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain NTPase_1 PF03266.15 CAM40333.1 - 0.014 15.3 0.2 0.046 13.6 0.0 2.0 2 1 0 2 2 2 0 NTPase Zeta_toxin PF06414.12 CAM40333.1 - 0.018 14.4 0.0 0.032 13.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin KTI12 PF08433.10 CAM40333.1 - 0.019 14.4 0.3 0.088 12.2 0.0 1.9 2 0 0 2 2 2 0 Chromatin associated protein KTI12 IstB_IS21 PF01695.17 CAM40333.1 - 0.031 14.0 0.0 0.064 13.0 0.0 1.6 2 0 0 2 2 1 0 IstB-like ATP binding protein Parvo_NS1 PF01057.17 CAM40333.1 - 0.034 13.2 0.1 0.07 12.2 0.0 1.5 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_26 PF13500.6 CAM40333.1 - 0.036 13.9 0.0 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 CAM40333.1 - 0.04 13.6 0.2 0.093 12.4 0.1 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Torsin PF06309.11 CAM40333.1 - 0.063 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Torsin ABC_tran PF00005.27 CAM40333.1 - 0.069 13.7 2.2 0.59 10.6 2.2 2.1 1 1 0 1 1 1 0 ABC transporter KAP_NTPase PF07693.14 CAM40333.1 - 0.07 12.3 0.0 0.13 11.5 0.0 1.2 1 1 0 1 1 1 0 KAP family P-loop domain AAA_19 PF13245.6 CAM40333.1 - 0.084 13.2 3.0 0.21 11.9 3.0 2.0 1 1 0 1 1 1 0 AAA domain Sars6 PF12133.8 CAM40333.1 - 0.093 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Open reading frame 6 from SARS coronavirus AAA_7 PF12775.7 CAM40333.1 - 0.098 12.2 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_3 PF07726.11 CAM40333.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 CAM40333.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase Thymidylate_kin PF02223.17 CAM40333.1 - 0.12 12.0 2.2 8.2 6.1 0.3 2.5 2 1 1 3 3 3 0 Thymidylate kinase Sigma54_activ_2 PF14532.6 CAM40333.1 - 0.16 12.1 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain CPT PF07931.12 CAM40333.1 - 0.16 11.8 2.6 1.6 8.5 0.0 2.7 2 1 1 3 3 3 0 Chloramphenicol phosphotransferase-like protein AAA_23 PF13476.6 CAM40333.1 - 0.17 12.3 0.8 0.38 11.2 0.8 1.6 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CAM40333.1 - 0.2 11.5 0.1 0.33 10.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain UvrD-helicase PF00580.21 CAM40333.1 - 5.2 6.5 5.8 1.6e+02 1.6 5.8 2.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain Elf1 PF05129.13 CAM40335.1 - 0.34 11.0 4.0 0.68 10.0 4.0 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like PseudoU_synth_2 PF00849.22 CAM40338.1 - 2.1e-18 66.9 0.0 1e-08 35.4 0.0 2.5 2 0 0 2 2 2 2 RNA pseudouridylate synthase S4 PF01479.25 CAM40338.1 - 0.0017 18.0 0.0 0.0065 16.2 0.0 2.0 2 0 0 2 2 2 1 S4 domain TPR_MLP1_2 PF07926.12 CAM40339.1 - 0.0039 17.3 18.0 0.051 13.6 0.9 3.4 3 0 0 3 3 3 2 TPR/MLP1/MLP2-like protein SHE3 PF17078.5 CAM40339.1 - 0.49 10.1 14.9 2.2 7.9 0.1 2.8 3 0 0 3 3 3 0 SWI5-dependent HO expression protein 3 DUF1154 PF06631.11 CAM40339.1 - 0.86 9.7 5.1 4.3 7.5 4.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1154) Lectin_N PF03954.14 CAM40339.1 - 0.94 9.2 5.8 0.46 10.2 0.3 2.5 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Syntaxin-6_N PF09177.11 CAM40339.1 - 2.2 8.9 12.6 0.2 12.2 0.8 3.5 3 0 0 3 3 3 0 Syntaxin 6, N-terminal BILBO1_N PF18281.1 CAM40340.1 - 2.5e-20 72.7 0.1 6.9e-20 71.3 0.0 1.8 2 0 0 2 2 2 1 BILBO1 N-terminal domain zf-C2H2_2 PF12756.7 CAM40341.1 - 2.1e-20 72.9 6.5 5.5e-14 52.3 0.6 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 CAM40341.1 - 0.00013 22.2 13.0 0.016 15.5 0.8 4.3 4 0 0 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 CAM40341.1 - 0.00043 20.9 8.7 0.2 12.6 0.1 4.3 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_12 PF18658.1 CAM40341.1 - 0.22 11.1 0.1 0.22 11.1 0.1 2.7 3 0 0 3 3 3 0 Zinc-finger C2H2-type Glycos_transf_1 PF00534.20 CAM40341.1 - 0.22 11.0 0.0 0.59 9.6 0.0 1.6 1 1 1 2 2 2 0 Glycosyl transferases group 1 zf-C2H2 PF00096.26 CAM40341.1 - 1.2 9.8 7.9 14 6.4 0.0 4.3 4 0 0 4 4 4 0 Zinc finger, C2H2 type PC_rep PF01851.22 CAM40343.2 - 0.014 15.8 11.3 8.2 7.1 0.0 6.1 6 0 0 6 6 6 0 Proteasome/cyclosome repeat IFT20 PF14931.6 CAM40344.1 - 4.2e-34 117.3 5.1 4.7e-34 117.1 5.1 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 VQ PF05678.14 CAM40344.1 - 0.039 13.4 4.5 0.72 9.4 0.1 2.9 3 0 0 3 3 3 0 VQ motif ISG65-75 PF11727.8 CAM40344.1 - 0.039 13.2 0.9 0.047 12.9 0.9 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein Haem_bd PF14376.6 CAM40344.1 - 0.062 13.2 0.1 0.081 12.9 0.1 1.2 1 0 0 1 1 1 0 Haem-binding domain Mannosyl_trans PF05007.13 CAM40346.1 - 5.1e-83 278.9 12.8 7.2e-83 278.4 12.8 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) GT87 PF09594.10 CAM40346.1 - 3.1e-10 40.2 12.6 3.1e-10 40.2 12.6 2.6 1 1 1 2 2 2 1 Glycosyltransferase family 87 PIG-U PF06728.13 CAM40346.1 - 6.1e-09 35.4 14.3 1.6e-08 34.0 14.0 1.8 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U Peptidase_C2 PF00648.21 CAM40347.1 - 3.2e-26 92.1 0.1 5.8e-13 48.5 0.0 4.1 4 0 0 4 4 4 3 Calpain family cysteine protease Calpain_III PF01067.22 CAM40347.1 - 0.0021 18.3 0.0 0.58 10.4 0.0 2.6 2 0 0 2 2 2 2 Calpain large subunit, domain III LRR_6 PF13516.6 CAM40347.1 - 0.0077 16.2 1.3 23 5.4 0.0 3.6 3 0 0 3 3 3 1 Leucine Rich repeat LRR_1 PF00560.33 CAM40347.1 - 0.11 13.1 3.9 40 5.3 0.2 4.0 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_4 PF12799.7 CAM40347.1 - 1.6 9.3 4.1 10 6.7 2.1 2.5 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM40347.1 - 1.7 8.5 3.9 35 4.3 0.2 2.8 2 1 0 2 2 2 0 Leucine rich repeat Cytochrom_B561 PF03188.16 CAM40348.1 - 3.5e-13 49.9 3.0 4.4e-11 43.1 1.2 2.3 2 0 0 2 2 2 2 Eukaryotic cytochrome b561 DUF4149 PF13664.6 CAM40348.1 - 0.021 15.1 0.8 0.041 14.2 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) zf-RING_UBOX PF13445.6 CAM40349.1 - 0.00065 19.7 7.7 0.0019 18.2 7.7 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CAM40349.1 - 0.0025 17.7 6.7 0.0025 17.7 6.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CAM40349.1 - 0.0075 16.1 4.7 0.0075 16.1 4.7 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) H_kinase_N PF12282.8 CAM40349.1 - 0.54 10.2 4.1 15 5.6 1.8 2.6 2 0 0 2 2 2 0 Signal transduction histidine kinase NFACT-R_1 PF05670.13 CAM40351.1 - 1.2e-43 148.2 0.0 1.7e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 NFACT protein RNA binding domain TcdA_TcdB PF12919.7 CAM40351.1 - 1.2 8.4 7.4 0.54 9.5 0.9 2.0 1 1 1 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain NACHT PF05729.12 CAM40352.1 - 0.01 15.8 0.1 0.03 14.2 0.1 1.9 1 1 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 CAM40352.1 - 0.023 15.0 0.0 0.18 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CAM40352.1 - 0.038 14.4 0.2 0.11 12.9 0.2 2.0 1 1 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 CAM40352.1 - 0.071 12.2 0.0 0.22 10.6 0.0 1.8 1 0 0 1 1 1 0 Type II/IV secretion system protein Fe-ADH PF00465.19 CAM40353.1 - 6.6e-110 367.3 0.4 7.5e-110 367.2 0.4 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 CAM40353.1 - 1.8e-18 67.2 0.2 4.6e-11 42.9 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase DUF1664 PF07889.12 CAM40354.1 - 0.00019 21.4 1.7 0.0004 20.4 1.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) DUF4164 PF13747.6 CAM40354.1 - 0.04 14.2 0.4 0.15 12.4 0.4 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) FlgN PF05130.12 CAM40354.1 - 0.044 14.3 7.5 0.042 14.4 5.5 2.0 2 0 0 2 2 2 0 FlgN protein ARA70 PF12489.8 CAM40354.1 - 0.071 13.3 3.8 0.14 12.4 1.7 2.5 3 0 0 3 3 3 0 Nuclear coactivator Baculo_PEP_C PF04513.12 CAM40354.1 - 0.087 12.9 2.0 0.18 11.8 2.0 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.15 CAM40354.1 - 0.088 12.4 2.5 0.062 12.9 0.5 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF4709 PF15821.5 CAM40354.1 - 0.33 11.2 2.7 0.8 10.0 2.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4709) Apolipoprotein PF01442.18 CAM40354.1 - 1.4 8.8 8.9 0.46 10.3 5.4 1.9 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain RsfS PF02410.15 CAM40356.1 - 2.3e-15 56.8 0.6 3.2e-15 56.4 0.6 1.2 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation Pkinase PF00069.25 CAM40357.1 - 2.8e-53 181.0 0.1 5.6e-39 134.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM40357.1 - 1.2e-35 123.0 0.1 1.5e-28 99.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Beta_helix PF13229.6 CAM40357.1 - 2e-29 102.5 7.5 3.6e-15 56.1 4.9 2.4 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 CAM40357.1 - 1.6e-24 86.5 0.6 9.6e-14 51.2 0.6 2.6 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) Kinase-like PF14531.6 CAM40357.1 - 3.2e-05 23.4 0.0 6.5e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like DUF1565 PF07602.11 CAM40357.1 - 0.0014 18.1 5.5 0.13 11.6 5.5 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1565) Pkinase_fungal PF17667.1 CAM40357.1 - 0.095 11.5 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 CAM40357.1 - 0.14 12.1 0.0 0.35 10.8 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Patatin PF01734.22 CAM40358.1 - 1.7e-22 80.6 0.7 3.1e-22 79.8 0.0 1.8 2 0 0 2 2 2 1 Patatin-like phospholipase DUF3336 PF11815.8 CAM40358.1 - 2.7e-07 30.4 0.0 4.7e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) WD40 PF00400.32 CAM40359.1 - 4.7e-07 30.4 9.7 0.00052 20.8 0.1 6.3 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM40359.1 - 0.017 15.4 0.0 5 7.5 0.0 4.3 5 1 0 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain IBR PF01485.21 CAM40361.1 - 1.7e-12 47.4 25.1 2e-08 34.3 14.2 4.4 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 CAM40361.1 - 5.3 7.5 46.2 0.09 13.1 13.0 4.0 2 1 1 3 3 3 0 Ring finger domain RRM_1 PF00076.22 CAM40362.1 - 1.7e-23 82.2 0.0 2.9e-13 49.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CAM40362.1 - 0.07 13.2 0.0 2.9 8.0 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif RRM_1 PF00076.22 CAM40363.1 - 1.5e-25 88.8 0.8 1e-14 54.1 0.1 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAM40363.1 - 0.022 14.9 0.0 0.56 10.4 0.0 2.6 2 1 0 2 2 2 0 RNA recognition motif RRM_Rrp7 PF17799.1 CAM40363.1 - 0.027 14.3 0.1 0.054 13.3 0.1 1.5 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain zf-CCCH PF00642.24 CAM40364.1 - 1.6e-07 31.0 0.4 2.3e-07 30.5 0.4 1.2 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CAM40364.1 - 8.6e-07 28.6 0.8 1.2e-06 28.2 0.8 1.2 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CAM40364.1 - 7.6e-05 22.6 0.6 0.00023 21.1 0.6 1.8 1 1 0 1 1 1 1 Zinc finger domain zf-CCCH_2 PF14608.6 CAM40364.1 - 0.00098 19.5 0.7 0.0016 18.8 0.7 1.3 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger Torus PF16131.5 CAM40364.1 - 0.11 13.2 0.0 0.16 12.7 0.0 1.3 1 0 0 1 1 1 0 Torus domain zf-CCCH_3 PF15663.5 CAM40364.1 - 0.14 12.4 0.1 0.26 11.5 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger containing family GYF_2 PF14237.6 CAM40365.1 - 3.3e-18 65.2 0.2 9.6e-18 63.7 0.2 1.9 1 0 0 1 1 1 1 GYF domain 2 DnaJ PF00226.31 CAM40365.1 - 1.2e-14 54.2 0.3 2.6e-14 53.1 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain HEAT PF02985.22 CAM40365.1 - 0.14 12.5 1.7 28 5.3 0.1 4.7 4 0 0 4 4 4 0 HEAT repeat DUF155 PF02582.14 CAM40366.1 - 6.8e-20 71.9 0.0 2.5e-19 70.1 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 Mito_carr PF00153.27 CAM40368.1 - 1.3e-09 37.9 6.6 0.06 13.3 0.4 5.0 4 1 0 4 4 4 4 Mitochondrial carrier protein CytB6-F_Fe-S PF08802.10 CAM40368.1 - 0.016 15.2 0.5 0.051 13.6 0.5 1.9 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit zf-C2H2_2 PF12756.7 CAM40369.1 - 6.8e-25 87.3 12.5 2.6e-18 66.2 2.8 3.2 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CAM40369.1 - 6.9e-12 45.3 8.4 3.5e-07 30.3 0.1 4.0 3 1 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CAM40369.1 - 5.9e-09 36.0 11.7 4.7e-05 23.6 1.0 3.7 3 1 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CAM40369.1 - 1.7e-07 31.0 8.5 0.0017 18.3 0.7 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_4 PF13894.6 CAM40369.1 - 2.1e-07 31.2 11.4 0.00079 20.1 0.6 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CAM40369.1 - 6.1e-05 23.3 17.3 0.0062 16.9 1.2 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_12 PF18658.1 CAM40369.1 - 0.0069 15.9 0.2 0.0069 15.9 0.2 3.6 2 1 1 3 3 3 1 Zinc-finger C2H2-type zf-LYAR PF08790.11 CAM40369.1 - 0.12 12.3 0.5 0.12 12.3 0.5 2.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf_C2H2_ZHX PF18387.1 CAM40369.1 - 0.17 11.6 17.1 2.5 7.8 0.3 4.7 5 0 0 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain PhoLip_ATPase_C PF16212.5 CAM40370.1 - 5.1e-40 137.8 14.6 5.1e-40 137.8 14.6 2.0 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CAM40370.1 - 1.8e-19 69.2 3.5 5.2e-19 67.7 3.5 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CAM40370.1 - 8.7e-10 39.2 0.1 0.00026 21.3 0.3 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CAM40370.1 - 4.8e-07 29.8 0.0 1.6e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CAM40370.1 - 5e-06 26.2 0.0 2.8e-05 23.7 0.0 2.1 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CAM40370.1 - 0.038 13.7 0.0 0.096 12.4 0.0 1.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase LRR_4 PF12799.7 CAM40371.2 - 3.5e-16 59.0 7.9 5.7e-05 23.4 0.4 6.9 4 2 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM40371.2 - 2.9e-07 30.1 18.5 0.00097 18.9 0.2 6.6 5 2 2 8 8 8 4 Leucine rich repeat LRR_9 PF14580.6 CAM40371.2 - 0.0021 17.6 0.4 0.084 12.4 0.1 2.8 2 0 0 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.33 CAM40371.2 - 0.098 13.3 9.9 70 4.6 0.1 6.8 7 1 0 7 7 7 0 Leucine Rich Repeat LRR_6 PF13516.6 CAM40371.2 - 0.25 11.5 7.9 90 3.5 0.1 5.9 6 0 0 6 6 6 0 Leucine Rich repeat TTL PF03133.15 CAM40372.1 - 8.1e-49 166.3 0.0 7.4e-30 104.1 0.0 3.1 3 0 0 3 3 3 3 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CAM40372.1 - 4.8e-07 29.3 0.0 0.013 14.7 0.0 2.5 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CAM40372.1 - 1.6e-06 27.6 0.0 0.034 13.4 0.0 2.6 3 0 0 3 3 3 2 Sugar-transfer associated ATP-grasp Dala_Dala_lig_C PF07478.13 CAM40372.1 - 0.047 13.2 0.2 0.13 11.8 0.1 1.7 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus DEAD PF00270.29 CAM40373.1 - 1.3e-13 51.1 0.0 2.8e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAM40373.1 - 2.3e-12 47.3 0.1 6e-12 45.9 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF742 PF05331.11 CAM40373.1 - 0.014 15.2 0.1 0.051 13.4 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF742) HTH_24 PF13412.6 CAM40373.1 - 0.15 11.7 0.0 0.38 10.4 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Spc7 PF08317.11 CAM40374.1 - 0.35 9.7 6.4 0.61 8.9 6.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Pol_alpha_B_N PF08418.10 CAM40374.1 - 3.1 7.7 4.4 2.9 7.8 0.3 2.4 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal SET PF00856.28 CAM40376.1 - 2.6e-08 34.4 0.0 6.2e-08 33.2 0.0 1.6 1 1 0 1 1 1 1 SET domain Dzip-like_N PF13815.6 CAM40378.2 - 0.012 15.6 0.3 0.029 14.3 0.3 1.8 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf_Hakai PF18408.1 CAM40378.2 - 0.055 13.2 0.6 0.14 11.9 0.6 1.7 1 0 0 1 1 1 0 C2H2 Hakai zinc finger domain zf-C2H2_4 PF13894.6 CAM40378.2 - 0.12 13.3 0.2 0.59 11.1 0.2 2.2 1 0 0 1 1 1 0 C2H2-type zinc finger DUF3357 PF11837.8 CAM40378.2 - 0.66 10.5 3.9 3.2 8.3 1.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) Pyridoxal_deC PF00282.19 CAM40379.1 - 5.7e-17 61.5 0.0 1e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 CAM40379.1 - 2.4e-11 43.2 0.0 1.1e-10 41.1 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CAM40379.1 - 0.0039 16.5 0.0 0.0061 15.9 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family zf-C3HC4_4 PF15227.6 CAM40380.1 - 2e-09 37.4 7.3 2e-09 37.4 7.3 3.8 3 1 1 4 4 4 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 CAM40380.1 - 5.7e-09 35.7 7.0 5.7e-09 35.7 7.0 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CAM40380.1 - 1.8e-08 34.1 6.3 1.8e-08 34.1 6.3 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CAM40380.1 - 5.1e-08 32.8 4.6 5.1e-08 32.8 4.6 3.1 3 0 0 3 3 3 1 RING-type zinc-finger zf-B_box PF00643.24 CAM40380.1 - 7.9e-08 32.3 23.0 1.8e-06 28.0 7.7 4.5 4 0 0 4 4 4 2 B-box zinc finger zf-RING_5 PF14634.6 CAM40380.1 - 2.9e-06 27.1 6.4 2.9e-06 27.1 6.4 3.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 CAM40380.1 - 4.5e-06 26.9 6.0 4.5e-06 26.9 6.0 3.5 3 0 0 3 3 3 1 Ring finger domain DUF1690 PF07956.11 CAM40380.1 - 0.013 15.9 1.3 0.025 15.0 1.1 1.5 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) Flg_hook PF02120.16 CAM40380.1 - 0.036 13.9 0.5 0.036 13.9 0.5 2.3 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK Apolipoprotein PF01442.18 CAM40380.1 - 0.054 13.4 8.2 0.11 12.3 8.2 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Anillin_N PF16018.5 CAM40382.1 - 0.093 13.3 0.2 0.093 13.3 0.2 3.6 4 1 1 5 5 5 0 Anillin N-terminus HIP1_clath_bdg PF16515.5 CAM40382.1 - 5.4 7.7 31.2 0.37 11.4 0.4 3.4 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 OpgC_C PF10129.9 CAM40384.1 - 0.0049 15.8 2.5 0.0065 15.4 2.5 1.1 1 0 0 1 1 1 1 OpgC protein CLP1_P PF16575.5 CAM40385.1 - 2.3e-36 125.4 0.0 3.7e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 CAM40385.1 - 0.0023 18.3 0.0 0.0064 16.9 0.0 1.7 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 CAM40385.1 - 0.0032 17.6 0.0 0.0061 16.7 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor PTH2 PF01981.16 CAM40386.1 - 9.8e-23 80.7 0.1 1.3e-22 80.3 0.1 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 TPR_2 PF07719.17 CAM40388.1 - 2.3e-05 24.2 0.1 0.13 12.5 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CAM40388.1 - 0.0044 16.8 0.1 0.75 9.7 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CAM40388.1 - 0.0085 16.2 0.0 0.23 11.8 0.0 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 CAM40388.1 - 0.02 15.0 0.0 0.17 12.0 0.5 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Rad50_zn_hook PF04423.14 CAM40388.1 - 0.14 12.0 0.5 0.49 10.3 0.5 2.0 1 0 0 1 1 1 0 Rad50 zinc hook motif DUF2256 PF10013.9 CAM40388.1 - 0.35 11.0 6.0 4.3 7.5 0.5 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) DnaJ PF00226.31 CAM40389.1 - 1.2e-11 44.6 0.0 2.9e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Plasmodium_Vir PF05795.11 CAM40389.1 - 0.0028 17.1 0.1 0.0036 16.8 0.1 1.2 1 0 0 1 1 1 1 Plasmodium vivax Vir protein HSP70 PF00012.20 CAM40390.1 - 2e-102 343.4 0.9 2.3e-102 343.2 0.9 1.0 1 0 0 1 1 1 1 Hsp70 protein Pneumo_ncap PF03246.13 CAM40390.1 - 0.042 12.6 0.4 0.063 12.0 0.4 1.2 1 0 0 1 1 1 0 Pneumovirus nucleocapsid protein Cep57_CLD PF14073.6 CAM40390.1 - 0.051 13.6 6.0 0.074 13.1 6.0 1.2 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 Trans_reg_C PF00486.28 CAM40390.1 - 0.13 12.4 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal Phage_GP20 PF06810.11 CAM40390.1 - 0.5 10.2 5.8 0.97 9.2 5.8 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF1690 PF07956.11 CAM40390.1 - 0.59 10.6 6.9 0.92 9.9 6.9 1.3 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) ApoO PF09769.9 CAM40390.1 - 0.69 9.9 4.7 0.74 9.8 1.0 2.2 2 0 0 2 2 2 0 Apolipoprotein O HSP70 PF00012.20 CAM40391.1 - 7.4e-259 860.0 8.7 8.6e-259 859.8 8.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CAM40391.1 - 1.5e-13 50.3 1.0 2.7e-12 46.2 0.3 2.5 2 1 0 2 2 2 1 MreB/Mbl protein HSP70 PF00012.20 CAM40392.1 - 4e-109 365.5 1.4 4.6e-109 365.3 1.4 1.0 1 0 0 1 1 1 1 Hsp70 protein FGGY_C PF02782.16 CAM40392.1 - 0.081 12.6 0.7 0.21 11.3 0.0 2.0 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Trans_reg_C PF00486.28 CAM40392.1 - 0.14 12.3 0.0 0.38 10.9 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal ApoO PF09769.9 CAM40392.1 - 1.1 9.2 4.8 0.88 9.5 1.0 2.2 2 0 0 2 2 2 0 Apolipoprotein O HSP70 PF00012.20 CAM40393.1 - 1.1e-258 859.4 8.8 1.3e-258 859.2 8.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CAM40393.1 - 1.6e-13 50.2 1.0 2.7e-12 46.2 0.3 2.5 2 1 0 2 2 2 1 MreB/Mbl protein HSP70 PF00012.20 CAM40394.1 - 1.6e-87 294.2 0.9 1.8e-87 294.0 0.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CAM40394.1 - 9e-06 24.7 0.3 0.00058 18.8 0.1 2.3 2 0 0 2 2 2 2 MreB/Mbl protein Pyridoxal_deC PF00282.19 CAM40395.2 - 9.5e-91 304.3 0.0 1.2e-90 304.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 CAM40395.2 - 0.0003 20.2 0.1 0.00038 19.8 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 CAM40395.2 - 0.084 11.5 0.0 0.23 10.1 0.1 1.6 2 0 0 2 2 2 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DUF2749 PF10907.8 CAM40397.1 - 0.1 12.8 0.0 21 5.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) AAA PF00004.29 CAM40398.2 - 1.8e-46 157.8 0.0 7.3e-40 136.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAM40398.2 - 1.4e-12 47.2 0.5 3.7e-09 36.2 0.2 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 CAM40398.2 - 3.5e-06 27.5 3.6 0.24 11.7 0.0 4.2 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 CAM40398.2 - 0.00018 21.8 0.1 0.84 9.9 0.0 3.1 2 1 1 3 3 3 2 AAA domain RuvB_N PF05496.12 CAM40398.2 - 0.0004 20.2 0.0 0.0013 18.5 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CAM40398.2 - 0.00049 20.1 0.1 0.06 13.4 0.0 3.2 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) Vps4_C PF09336.10 CAM40398.2 - 0.0023 17.9 0.1 0.012 15.6 0.0 2.2 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain TIP49 PF06068.13 CAM40398.2 - 0.0076 15.5 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 CAM40398.2 - 0.0081 16.3 0.2 0.9 9.7 0.0 3.1 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 CAM40398.2 - 0.016 14.9 0.1 0.54 10.0 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 CAM40398.2 - 0.018 14.3 0.0 6.3 6.0 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin RNA_helicase PF00910.22 CAM40398.2 - 0.019 15.4 0.0 0.5 10.8 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 CAM40398.2 - 0.025 14.1 0.1 0.98 8.9 0.0 2.6 2 1 0 2 2 2 0 P-loop containing dynein motor region Rad17 PF03215.15 CAM40398.2 - 0.038 13.9 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Mg_chelatase PF01078.21 CAM40398.2 - 0.04 13.3 0.0 0.097 12.0 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 CAM40398.2 - 0.046 13.8 0.0 0.14 12.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain (Cdc48 subfamily) ABC_tran PF00005.27 CAM40398.2 - 0.052 14.1 0.0 5.5 7.5 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_25 PF13481.6 CAM40398.2 - 0.065 12.8 0.9 2.5 7.6 0.0 3.4 4 0 0 4 4 4 0 AAA domain HSP70 PF00012.20 CAM40399.1 - 1.1e-80 271.6 0.5 1.3e-80 271.3 0.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CAM40399.1 - 0.0003 19.7 0.2 0.022 13.6 0.1 2.3 2 0 0 2 2 2 2 MreB/Mbl protein TSNAXIP1_N PF15739.5 CAM40400.2 - 2.1e-05 24.9 0.3 2.1e-05 24.9 0.3 3.3 2 1 1 3 3 3 1 Translin-associated factor X-interacting N-terminus ERM PF00769.19 CAM40400.2 - 0.0083 16.0 0.7 0.0083 16.0 0.7 3.9 2 1 2 4 4 4 2 Ezrin/radixin/moesin family AAA_13 PF13166.6 CAM40400.2 - 0.024 13.3 4.9 0.04 12.6 4.9 1.2 1 0 0 1 1 1 0 AAA domain Uso1_p115_C PF04871.13 CAM40400.2 - 0.029 14.7 12.6 0.034 14.5 8.4 2.8 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region T5orf172 PF10544.9 CAM40400.2 - 0.2 12.2 0.4 3.3 8.3 0.0 2.7 2 0 0 2 2 2 0 T5orf172 domain Prefoldin PF02996.17 CAM40400.2 - 4 7.4 8.2 24 4.8 0.1 3.9 4 1 0 4 4 4 0 Prefoldin subunit Cofilin_ADF PF00241.20 CAM40401.1 - 3.5e-10 39.7 0.0 1.8e-07 30.9 0.0 2.4 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein GHBP PF12772.7 CAM40401.1 - 0.012 15.1 0.7 0.086 12.4 0.0 2.0 2 0 0 2 2 2 0 Growth hormone receptor binding RecT PF03837.14 CAM40401.1 - 0.097 12.1 0.1 0.25 10.8 0.0 1.6 2 0 0 2 2 2 0 RecT family Reticulon PF02453.17 CAM40402.1 - 7.1e-27 94.3 7.6 9.4e-27 93.9 7.6 1.2 1 0 0 1 1 1 1 Reticulon DUF3292 PF11696.8 CAM40402.1 - 0.0011 17.5 1.4 0.0012 17.3 0.7 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3292) PrgI PF12666.7 CAM40402.1 - 0.1 13.3 4.3 0.44 11.3 0.3 2.3 2 0 0 2 2 2 0 PrgI family protein Leu_Phe_trans PF03588.14 CAM40403.1 - 0.00032 20.2 0.3 0.25 10.9 0.0 2.2 2 0 0 2 2 2 2 Leucyl/phenylalanyl-tRNA protein transferase FTHFS PF01268.19 CAM40404.1 - 1.8e-253 841.8 0.0 2.1e-253 841.6 0.0 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase RRM_1 PF00076.22 CAM40405.1 - 3.1e-16 59.0 0.0 5.8e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CAM40405.1 - 0.00094 19.1 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF3138 PF11336.8 CAM40405.1 - 0.011 14.5 0.8 0.014 14.0 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) PHM7_cyt PF14703.6 CAM40405.1 - 0.15 12.3 0.5 4.2 7.6 0.0 2.2 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter MSP1a PF11670.8 CAM40407.1 - 0.098 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) AAA PF00004.29 CAM40408.1 - 1.4e-13 51.4 0.0 3.1e-13 50.3 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 CAM40408.1 - 2e-11 44.1 0.0 3.5e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 CAM40408.1 - 3.8e-08 33.3 0.0 5.7e-06 26.2 0.0 2.3 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 CAM40408.1 - 4.9e-05 23.6 0.0 0.00044 20.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CAM40408.1 - 0.0002 21.3 0.0 0.00041 20.2 0.0 1.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 CAM40408.1 - 0.004 17.6 1.1 0.028 14.8 0.0 2.6 2 2 1 3 3 3 1 AAA ATPase domain DUF2075 PF09848.9 CAM40408.1 - 0.0065 15.8 0.0 0.0093 15.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) RuvB_N PF05496.12 CAM40408.1 - 0.0069 16.1 0.0 0.04 13.7 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 CAM40408.1 - 0.0099 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CAM40408.1 - 0.012 15.6 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CAM40408.1 - 0.032 14.4 0.0 0.061 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CAM40408.1 - 0.065 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 CAM40408.1 - 0.079 12.7 0.0 0.16 11.7 0.0 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 CAM40408.1 - 0.097 12.4 0.0 0.28 10.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 CAM40408.1 - 0.12 12.1 0.2 0.87 9.3 0.0 2.1 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_assoc_2 PF16193.5 CAM40408.1 - 0.14 12.5 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA C-terminal domain AAA_19 PF13245.6 CAM40408.1 - 0.17 12.2 0.1 0.4 11.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain ubiquitin PF00240.23 CAM40411.1 - 0.00011 21.9 0.0 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family TPR_12 PF13424.6 CAM40412.2 - 0.0057 16.9 4.7 0.035 14.4 1.7 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat SH3_2 PF07653.17 CAM40414.1 - 2.3e-06 27.2 0.0 3.9e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CAM40414.1 - 2e-05 24.4 0.0 3e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CAM40414.1 - 0.00042 19.9 0.0 0.00088 18.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain CortBP2 PF09727.9 CAM40414.1 - 0.006 16.5 0.3 0.009 15.9 0.3 1.2 1 0 0 1 1 1 1 Cortactin-binding protein-2 Tmemb_9 PF05434.11 CAM40414.1 - 0.3 11.0 0.7 0.57 10.1 0.7 1.4 1 0 0 1 1 1 0 TMEM9 Miga PF10265.9 CAM40414.1 - 0.95 8.4 3.3 1.2 8.1 3.3 1.1 1 0 0 1 1 1 0 Mitoguardin GRAM PF02893.20 CAM40417.1 - 4.9e-11 42.5 0.1 1.1e-10 41.4 0.1 1.6 1 0 0 1 1 1 1 GRAM domain SPA PF08616.10 CAM40418.2 - 1.6e-29 102.1 0.0 3.5e-29 101.1 0.0 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 CAM40418.2 - 0.0005 18.9 0.0 0.034 12.8 0.0 2.2 1 1 1 2 2 2 2 Transport protein Avl9 DENN PF02141.21 CAM40418.2 - 0.00093 19.2 0.2 0.0028 17.6 0.0 2.0 1 1 1 2 2 2 1 DENN (AEX-3) domain DUF2347 PF09804.9 CAM40418.2 - 0.024 14.2 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) HEAT_EZ PF13513.6 CAM40418.2 - 0.35 11.4 4.3 3.9 8.1 0.1 3.8 4 0 0 4 4 4 0 HEAT-like repeat TPR_1 PF00515.28 CAM40419.1 - 8.3e-25 85.5 7.7 8.7e-08 31.7 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 CAM40419.1 - 1.4e-17 62.3 13.9 2.2e-07 30.5 0.1 4.7 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 CAM40419.1 - 2.1e-14 52.5 4.9 0.00014 21.8 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CAM40419.1 - 1.6e-13 50.1 5.9 4.2e-06 26.3 0.6 3.6 1 1 2 3 3 3 3 TPR repeat TPR_17 PF13431.6 CAM40419.1 - 6.1e-09 35.6 2.8 0.0065 16.8 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CAM40419.1 - 2.3e-08 33.5 1.0 0.048 13.7 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CAM40419.1 - 4.7e-08 33.5 4.9 0.00032 21.3 0.0 3.0 3 1 0 4 4 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 CAM40419.1 - 2e-07 31.2 4.4 6.6e-05 23.1 0.3 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CAM40419.1 - 2e-07 31.2 0.1 0.023 15.5 0.0 4.0 1 1 2 3 3 3 2 Tetratricopeptide repeat SGT1 PF07093.11 CAM40419.1 - 6.3e-07 28.2 2.3 9.1e-07 27.7 2.3 1.2 1 0 0 1 1 1 1 SGT1 protein STI1 PF17830.1 CAM40419.1 - 4.4e-06 26.5 10.0 0.00094 19.1 0.1 3.4 4 0 0 4 4 2 2 STI1 domain TPR_19 PF14559.6 CAM40419.1 - 0.00015 22.2 3.6 0.14 12.7 0.1 2.9 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 CAM40419.1 - 0.00052 20.1 0.1 0.01 16.0 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TOM20_plant PF06552.12 CAM40419.1 - 0.0013 18.6 0.7 0.015 15.1 0.2 2.9 2 1 1 3 3 3 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_10 PF13374.6 CAM40419.1 - 0.0036 17.1 6.9 2 8.4 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 CAM40419.1 - 0.0073 16.9 2.8 0.69 10.7 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CAM40419.1 - 0.012 15.8 3.9 0.17 12.1 0.6 2.7 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 CAM40419.1 - 0.037 14.1 6.5 1 9.5 0.5 3.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain NRBF2_MIT PF17169.4 CAM40419.1 - 0.14 12.3 0.3 0.41 10.9 0.3 1.7 1 0 0 1 1 1 0 MIT domain of nuclear receptor-binding factor 2 Fis1_TPR_C PF14853.6 CAM40419.1 - 0.24 11.5 2.6 8.6 6.5 0.0 3.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat GerD PF17898.1 CAM40419.1 - 0.71 9.8 3.8 1.9 8.4 1.0 2.7 2 0 0 2 2 2 0 Spore germination GerD central core domain Smg4_UPF3 PF03467.15 CAM40419.1 - 0.85 9.6 4.9 0.6 10.1 1.8 2.3 3 0 0 3 3 3 0 Smg-4/UPF3 family Methyltransf_5 PF01795.19 CAM40420.1 - 0.0078 15.7 1.0 0.012 15.2 1.0 1.2 1 0 0 1 1 1 1 MraW methylase family DUF4168 PF13767.6 CAM40420.1 - 0.016 16.3 0.6 0.029 15.6 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4168) DSBA PF01323.20 CAM40420.1 - 0.079 12.7 0.8 0.12 12.1 0.8 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain VIT1 PF01988.19 CAM40420.1 - 0.31 10.9 1.5 0.53 10.1 1.5 1.3 1 0 0 1 1 1 0 VIT family TMA7 PF09072.10 CAM40421.1 - 5.9e-16 59.0 14.0 6.4e-16 58.9 14.0 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Sod_Fe_N PF00081.22 CAM40423.1 - 5.9e-06 26.7 0.1 8.8e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.18 CAM40423.1 - 3.9e-05 23.7 0.0 9.9e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain zf-CCCH PF00642.24 CAM40424.1 - 4e-06 26.6 2.1 4e-06 26.6 2.1 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CAM40424.1 - 3.6e-05 23.7 4.5 7.3e-05 22.7 4.5 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 CAM40424.1 - 5.9e-05 22.8 2.5 0.00012 21.8 2.5 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CAM40424.1 - 0.12 12.9 1.9 0.27 11.8 1.9 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger DUF872 PF05915.12 CAM40425.1 - 2e-05 24.7 0.4 2.4e-05 24.5 0.4 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) Cpn60_TCP1 PF00118.24 CAM40428.1 - 1e-67 228.9 8.9 3.8e-67 227.0 8.9 1.7 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family TcpQ PF10671.9 CAM40428.1 - 0.2 11.8 1.1 3.5 7.8 0.0 3.1 3 1 0 3 3 3 0 Toxin co-regulated pilus biosynthesis protein Q RabGAP-TBC PF00566.18 CAM40430.1 - 4.7e-34 117.9 0.3 3.2e-33 115.2 0.3 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF4597 PF15366.6 CAM40434.2 - 0.0037 17.0 0.4 0.0037 17.0 0.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4597) GAT PF03127.14 CAM40434.2 - 0.055 13.8 0.0 0.19 12.1 0.0 2.0 1 0 0 1 1 1 0 GAT domain DUF737 PF05300.11 CAM40434.2 - 2.2 8.6 7.7 1 9.7 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF737) PPR_2 PF13041.6 CAM40435.1 - 0.0025 18.0 0.0 41 4.5 0.0 4.3 4 0 0 4 4 4 2 PPR repeat family TPR_7 PF13176.6 CAM40435.1 - 0.0063 16.5 2.5 59 4.0 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat PPR PF01535.20 CAM40435.1 - 0.011 16.0 1.5 27 5.3 0.0 5.3 7 0 0 7 7 7 0 PPR repeat DUF4911 PF16256.5 CAM40436.2 - 0.014 15.3 0.1 0.03 14.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4911) Aldedh PF00171.22 CAM40437.1 - 2e-118 395.9 0.0 2.5e-118 395.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 CAM40437.1 - 0.0093 15.4 0.0 0.031 13.7 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Med27 PF11571.8 CAM40437.1 - 0.094 13.1 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Mediator complex subunit 27 Pkinase PF00069.25 CAM40438.1 - 1.2e-52 178.9 0.0 1.9e-52 178.2 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM40438.1 - 1.3e-17 64.0 0.0 1.6e-17 63.7 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CAM40438.1 - 5.6e-07 29.1 0.1 1e-06 28.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CAM40438.1 - 0.0012 18.8 0.2 0.0018 18.2 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CAM40438.1 - 0.0028 17.0 0.0 0.0074 15.6 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CAM40438.1 - 0.023 13.5 0.1 0.04 12.7 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase GAGA_bind PF06217.12 CAM40439.1 - 1.5 9.0 7.6 0.26 11.5 1.0 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family DUF572 PF04502.13 CAM40439.1 - 2 8.0 10.6 0.43 10.1 1.4 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) FAM76 PF16046.5 CAM40439.1 - 7.4 5.8 14.6 5.4 6.3 2.6 2.2 2 0 0 2 2 2 0 FAM76 protein zf-CHCC PF10276.9 CAM40443.1 - 0.00041 20.3 2.9 0.00041 20.3 2.9 1.9 2 0 0 2 2 2 1 Zinc-finger domain Gp_dh_C PF02800.20 CAM40444.1 - 9.5e-64 213.8 0.0 1.5e-63 213.1 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CAM40444.1 - 1.2e-29 102.6 0.0 2.3e-29 101.7 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 CAM40444.1 - 0.0062 16.7 1.1 0.012 15.8 0.1 2.0 3 0 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 CAM40444.1 - 0.052 14.4 0.0 0.096 13.5 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DUF2817 PF10994.8 CAM40445.1 - 1.5e-108 363.2 0.5 1.7e-108 363.0 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) AstE_AspA PF04952.14 CAM40445.1 - 1.2e-05 24.5 0.0 2.7e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family TPR_1 PF00515.28 CAM40447.1 - 2.5e-99 321.4 31.4 7.3e-08 31.9 0.7 15.0 15 0 0 15 15 15 14 Tetratricopeptide repeat TPR_2 PF07719.17 CAM40447.1 - 1.8e-82 264.9 43.6 1.1e-06 28.3 0.7 15.5 15 0 0 15 15 15 14 Tetratricopeptide repeat TPR_11 PF13414.6 CAM40447.1 - 7.2e-60 198.4 31.8 1e-08 34.7 1.7 13.7 5 2 8 13 13 13 11 TPR repeat TPR_8 PF13181.6 CAM40447.1 - 1.9e-55 180.5 25.6 4.9e-05 23.2 0.7 13.5 14 0 0 14 14 14 11 Tetratricopeptide repeat TPR_16 PF13432.6 CAM40447.1 - 3.1e-51 171.7 46.0 7.9e-08 32.8 1.0 9.8 6 3 3 9 9 9 9 Tetratricopeptide repeat TPR_17 PF13431.6 CAM40447.1 - 4.9e-42 139.3 22.9 1.2e-05 25.3 0.1 12.9 13 0 0 13 13 13 8 Tetratricopeptide repeat TPR_9 PF13371.6 CAM40447.1 - 3.4e-40 136.1 34.2 1.1e-05 25.5 0.1 11.9 4 3 8 12 12 12 11 Tetratricopeptide repeat TPR_12 PF13424.6 CAM40447.1 - 3.9e-33 113.6 49.6 2.7e-06 27.5 1.6 10.2 8 3 3 11 11 10 7 Tetratricopeptide repeat TPR_7 PF13176.6 CAM40447.1 - 1.9e-29 99.5 28.1 0.0087 16.0 0.1 13.6 13 1 1 14 14 14 7 Tetratricopeptide repeat TPR_14 PF13428.6 CAM40447.1 - 1.6e-21 75.1 35.2 0.0036 18.0 0.0 13.6 4 2 11 15 15 15 5 Tetratricopeptide repeat TPR_6 PF13174.6 CAM40447.1 - 1.2e-20 72.7 42.6 0.14 12.9 0.0 13.9 15 0 0 15 15 14 6 Tetratricopeptide repeat TPR_19 PF14559.6 CAM40447.1 - 1.7e-16 60.4 26.8 0.0014 19.1 1.0 9.7 5 3 4 10 10 10 5 Tetratricopeptide repeat TPR_10 PF13374.6 CAM40447.1 - 7.9e-11 41.5 40.1 0.093 12.6 0.1 11.6 13 0 0 13 13 12 5 Tetratricopeptide repeat SHNi-TPR PF10516.9 CAM40447.1 - 1.5e-09 37.2 15.9 0.46 10.0 0.0 10.2 10 0 0 10 10 10 2 SHNi-TPR ANAPC3 PF12895.7 CAM40447.1 - 5.4e-06 26.5 28.9 0.044 14.0 1.0 7.8 5 2 3 8 8 8 2 Anaphase-promoting complex, cyclosome, subunit 3 Coatomer_E PF04733.14 CAM40447.1 - 0.0042 16.5 0.5 6.4 6.1 0.0 3.7 4 0 0 4 4 4 1 Coatomer epsilon subunit TPR_20 PF14561.6 CAM40447.1 - 0.0055 17.0 10.2 13 6.2 0.0 6.2 5 2 1 7 7 7 0 Tetratricopeptide repeat NARP1 PF12569.8 CAM40447.1 - 0.0057 15.6 9.8 0.065 12.1 0.1 4.0 2 1 2 4 4 4 1 NMDA receptor-regulated protein 1 BTAD PF03704.17 CAM40447.1 - 0.015 15.8 21.7 0.83 10.1 0.5 6.3 5 2 1 7 7 7 0 Bacterial transcriptional activator domain DUF3856 PF12968.7 CAM40447.1 - 0.018 15.1 8.3 33 4.5 0.0 7.2 4 2 1 7 7 7 0 Domain of Unknown Function (DUF3856) T2SSF PF00482.23 CAM40447.1 - 0.024 14.6 0.0 0.077 12.9 0.0 1.9 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F MIT PF04212.18 CAM40447.1 - 0.1 12.7 0.3 0.1 12.7 0.3 9.1 10 1 1 11 11 10 0 MIT (microtubule interacting and transport) domain NdhN PF11909.8 CAM40447.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 NADH-quinone oxidoreductase cyanobacterial subunit N RPN13_C PF16550.5 CAM40447.1 - 0.15 12.2 0.4 19 5.5 0.1 4.2 6 0 0 6 6 3 0 UCH-binding domain TPR_4 PF07721.14 CAM40447.1 - 4.7 8.1 19.5 1e+02 4.0 0.0 8.4 9 0 0 9 9 8 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CAM40447.1 - 5 7.3 27.7 3.1 7.9 0.1 7.6 7 2 2 9 9 7 0 Fis1 C-terminal tetratricopeptide repeat LSM PF01423.22 CAM40448.1 - 1.2e-07 31.3 0.2 2.1e-07 30.6 0.2 1.4 1 1 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CAM40448.1 - 0.088 13.0 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain KH_8 PF17903.1 CAM40449.1 - 8.4e-26 89.9 0.0 1.8e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain DUF21 PF01595.20 CAM40451.1 - 3.4e-26 92.0 5.3 7.1e-26 91.0 5.3 1.5 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 CAM40451.1 - 3.6e-06 27.3 0.1 0.0033 17.8 0.0 2.8 3 0 0 3 3 3 2 CBS domain DUF5325 PF17259.2 CAM40451.1 - 4.6 7.2 8.3 0.13 12.2 0.5 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5325) eIF-3_zeta PF05091.12 CAM40452.1 - 6.6e-93 312.4 0.0 7.6e-93 312.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pkinase PF00069.25 CAM40453.1 - 9.3e-66 221.9 0.0 1.3e-65 221.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM40453.1 - 3.5e-45 154.3 0.0 5.4e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAM40453.1 - 0.0015 17.4 0.0 0.0026 16.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CAM40453.1 - 0.004 16.5 0.0 0.0078 15.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like G8 PF10162.9 CAM40453.1 - 0.022 14.9 0.5 2.4 8.2 0.1 3.0 2 0 0 2 2 2 0 G8 domain Seadorna_VP7 PF07387.11 CAM40453.1 - 0.078 12.0 0.0 0.48 9.4 0.0 2.0 2 0 0 2 2 2 0 Seadornavirus VP7 DUF485 PF04341.12 CAM40453.1 - 2 8.5 6.0 21 5.2 4.3 2.8 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Kinesin PF00225.23 CAM40454.1 - 1.8e-81 273.7 0.0 1.8e-81 273.7 0.0 2.6 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CAM40454.1 - 2.7e-19 69.6 0.1 1.4e-18 67.3 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding PKcGMP_CC PF16808.5 CAM40454.1 - 0.0059 16.4 1.0 0.0059 16.4 1.0 6.8 6 0 0 6 6 6 1 Coiled-coil N-terminus of cGMP-dependent protein kinase Fer4_24 PF18109.1 CAM40454.1 - 0.11 12.8 0.5 0.5 10.7 0.5 2.3 1 0 0 1 1 1 0 Ferredoxin I 4Fe-4S cluster domain tRNA_m1G_MT PF01746.21 CAM40455.1 - 2.3e-18 66.6 0.1 4.9e-18 65.5 0.0 1.5 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase F_actin_bund_C PF18060.1 CAM40455.1 - 0.083 13.0 7.7 0.17 12.0 7.7 1.5 1 0 0 1 1 1 0 F actin bundling C terminal DDE_Tnp_1_3 PF13612.6 CAM40455.1 - 0.16 12.0 0.0 0.39 10.7 0.0 1.6 2 0 0 2 2 2 0 Transposase DDE domain GHMP_kinases_N PF00288.26 CAM40456.1 - 5.1e-09 36.2 0.4 5.1e-09 36.2 0.4 2.1 3 0 0 3 3 3 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CAM40456.1 - 7.7e-07 29.4 0.1 1.8e-06 28.2 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal PPR_3 PF13812.6 CAM40458.1 - 0.011 15.8 0.0 3.4 7.8 0.0 3.9 6 0 0 6 6 6 0 Pentatricopeptide repeat domain SAM_decarbox PF01536.16 CAM40459.1 - 3.3e-89 299.4 0.0 3.8e-89 299.2 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase SAM_decarbox PF01536.16 CAM40460.1 - 1.1e-13 51.0 0.1 3.7e-08 32.8 0.0 2.1 2 0 0 2 2 2 2 Adenosylmethionine decarboxylase tRNA-synt_1 PF00133.22 CAM40461.1 - 8.5e-193 641.9 0.0 9.2e-192 638.5 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CAM40461.1 - 5.6e-34 117.3 0.0 9.5e-34 116.5 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Val_tRNA-synt_C PF10458.9 CAM40461.1 - 4.1e-15 55.8 1.5 9.5e-15 54.6 1.5 1.7 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1g PF09334.11 CAM40461.1 - 7.1e-14 51.4 0.2 3.6e-07 29.3 0.0 3.8 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 CAM40461.1 - 8.7e-08 31.9 0.0 0.00046 19.8 0.0 2.6 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 CAM40461.1 - 0.01 15.2 0.3 1.2 8.4 0.1 3.0 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.25 CAM40461.1 - 0.053 12.8 0.1 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) TRAP_beta PF05753.14 CAM40463.1 - 2.4e-10 40.1 2.4 2.6e-09 36.7 2.4 2.4 1 1 0 1 1 1 1 Translocon-associated protein beta (TRAPB) DUF11 PF01345.18 CAM40463.1 - 2.9e-08 33.9 0.9 1.1e-07 32.0 0.9 2.0 1 1 0 1 1 1 1 Domain of unknown function DUF11 CARDB PF07705.11 CAM40463.1 - 1.9e-05 24.8 0.5 2.9e-05 24.3 0.5 1.3 1 0 0 1 1 1 1 CARDB NPCBM_assoc PF10633.9 CAM40463.1 - 0.011 15.9 0.1 0.049 13.9 0.1 2.0 1 1 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase DUF5006 PF16397.5 CAM40463.1 - 0.025 13.8 0.3 0.037 13.2 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5006) TPH PF13868.6 CAM40465.1 - 1.1e-41 142.6 131.8 1.1e-41 142.6 131.8 1.8 2 0 0 2 2 2 1 Trichohyalin-plectin-homology domain RRM_1 PF00076.22 CAM40466.1 - 4e-08 33.0 0.0 6.1e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CAM40466.1 - 0.029 14.0 0.0 0.06 13.0 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMG-CoA_red PF00368.18 CAM40467.1 - 4.9e-134 447.0 4.8 5.7e-134 446.7 4.8 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Phage_integrase PF00589.22 CAM40468.1 - 7.8e-07 29.0 0.0 6.5e-06 26.0 0.0 2.7 2 0 0 2 2 2 1 Phage integrase family RVT_1 PF00078.27 CAM40468.1 - 0.003 17.1 0.0 0.0083 15.7 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A17 PF05380.13 CAM40468.1 - 0.0049 16.9 0.1 0.056 13.4 0.0 2.4 1 1 1 2 2 2 1 Pao retrotransposon peptidase Phage_integrase PF00589.22 CAM40469.1 - 5.7e-06 26.2 0.1 4.4e-05 23.3 0.0 2.6 3 1 0 3 3 3 1 Phage integrase family RVT_1 PF00078.27 CAM40469.1 - 0.002 17.7 0.0 0.006 16.1 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A17 PF05380.13 CAM40469.1 - 0.007 16.4 1.3 0.044 13.8 0.0 2.5 2 1 1 3 3 3 1 Pao retrotransposon peptidase Phage_integrase PF00589.22 CAM40470.1 - 1.5e-06 28.1 0.0 1.1e-05 25.3 0.0 2.5 2 1 0 2 2 2 1 Phage integrase family RVT_1 PF00078.27 CAM40470.1 - 0.0015 18.1 0.0 0.0049 16.4 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A17 PF05380.13 CAM40470.1 - 0.0024 17.9 0.1 0.038 14.0 0.0 2.4 1 1 1 2 2 2 1 Pao retrotransposon peptidase RVT_1 PF00078.27 CAM40471.1 - 0.0013 18.3 0.0 0.0029 17.2 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A17 PF05380.13 CAM40471.1 - 0.0015 18.6 0.1 0.027 14.5 0.0 2.2 1 1 1 2 2 2 1 Pao retrotransposon peptidase Ribosomal_S26e PF01283.19 CAM40472.1 - 8.6e-36 122.7 3.6 9.1e-36 122.6 3.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Lebercilin PF15619.6 CAM40473.1 - 0.0012 18.5 14.1 0.0012 18.5 14.1 3.1 2 1 1 3 3 3 1 Ciliary protein causing Leber congenital amaurosis disease DUF4686 PF15742.5 CAM40473.1 - 0.017 14.3 35.5 0.24 10.5 5.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4686) DUF2274 PF10038.9 CAM40473.1 - 0.07 13.6 0.3 0.24 11.9 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2274) DUF4250 PF14056.6 CAM40473.1 - 0.94 9.5 3.8 0.97 9.4 0.6 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4250) SepRS_C PF18006.1 CAM40474.2 - 0.25 11.5 0.4 2 8.6 0.1 2.3 2 0 0 2 2 2 0 O-phosphoseryl-tRNA synthetase C-terminal domain tRNA-synt_1c PF00749.21 CAM40477.1 - 1.2e-104 349.7 0.1 1.7e-104 349.1 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 CAM40477.1 - 5e-34 117.7 0.2 1.1e-33 116.5 0.2 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain HA2 PF04408.23 CAM40478.1 - 2.6e-13 50.2 0.0 2.6e-13 50.2 0.0 2.8 2 1 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CAM40478.1 - 9e-10 38.9 0.0 4.9e-09 36.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CAM40478.1 - 4.4e-09 36.3 0.0 6.9e-08 32.5 0.0 2.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 CAM40478.1 - 3.5e-07 30.5 0.0 7e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 CAM40478.1 - 7.2e-07 29.6 1.8 1e-05 25.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain ResIII PF04851.15 CAM40478.1 - 0.00015 21.9 0.0 0.00056 19.9 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CAM40478.1 - 0.00019 21.8 0.0 0.00094 19.5 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CAM40478.1 - 0.034 13.9 0.0 0.085 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 CAM40478.1 - 0.15 11.4 0.0 0.15 11.4 0.0 2.2 3 0 0 3 3 3 0 KaiC AAA_16 PF13191.6 CAM40478.1 - 0.5 10.7 0.0 0.5 10.7 0.0 3.2 2 1 1 3 3 3 0 AAA ATPase domain AAA_23 PF13476.6 CAM40478.1 - 1.4 9.3 0.0 1.4 9.3 0.0 2.6 2 0 0 2 2 1 0 AAA domain DUF4890 PF16231.5 CAM40478.1 - 2.8 8.5 18.0 7.2 7.1 18.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4890) AAA_11 PF13086.6 CAM40478.1 - 5.4 6.7 0.0 5.4 6.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain Ank_4 PF13637.6 CAM40479.1 - 1.2e-30 105.5 6.2 1.4e-08 35.1 0.0 6.5 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 CAM40479.1 - 2.6e-30 104.8 3.9 6e-10 39.6 1.1 4.2 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CAM40479.1 - 1.8e-26 89.3 4.4 0.0016 18.7 0.0 7.6 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.6 CAM40479.1 - 1.7e-23 82.3 9.3 5.5e-07 29.8 0.3 6.3 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 CAM40479.1 - 1.7e-22 78.8 6.7 0.00038 20.8 0.0 7.3 7 0 0 7 7 7 7 Ankyrin repeat Sensor PF13796.6 CAM40480.1 - 0.0093 16.0 0.6 0.013 15.5 0.6 1.2 1 0 0 1 1 1 1 Putative sensor Metallophos PF00149.28 CAM40481.2 - 2.9e-09 37.7 0.0 4.8e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase XPC-binding PF09280.11 CAM40483.1 - 9.7e-16 57.3 0.1 2e-15 56.3 0.1 1.5 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 CAM40483.1 - 7.2e-13 48.1 0.0 1.4e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 CAM40483.1 - 9e-10 38.3 6.3 1.9e-06 27.6 1.2 2.5 2 0 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.8 CAM40483.1 - 2.5e-06 27.2 0.2 6.2e-06 26.0 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 CAM40483.1 - 0.0052 16.6 0.0 0.029 14.2 0.0 2.1 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain MCM_N PF14551.6 CAM40483.1 - 0.0081 16.7 0.0 0.018 15.6 0.0 1.5 1 0 0 1 1 1 1 MCM N-terminal domain MORN PF02493.20 CAM40484.1 - 3.5e-93 300.3 109.3 3e-10 39.4 2.5 15.1 15 0 0 15 15 15 15 MORN repeat Peptidase_S55 PF05580.12 CAM40484.1 - 0.085 12.8 9.9 1.4 8.9 0.2 5.1 3 2 2 5 5 5 0 SpoIVB peptidase S55 DUF2158 PF09926.9 CAM40484.1 - 1.7 8.4 7.0 6.9 6.5 0.0 5.1 4 1 3 8 8 8 0 Uncharacterized small protein (DUF2158) BAR PF03114.18 CAM40485.1 - 9.6e-05 22.1 3.5 0.00022 21.0 3.4 1.5 1 1 0 1 1 1 1 BAR domain Vsr PF03852.15 CAM40485.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 DNA mismatch endonuclease Vsr Ribosomal_L6 PF00347.23 CAM40487.1 - 2.4e-25 89.0 2.4 3.5e-14 53.2 0.3 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Glyco_hydro_65C PF03633.15 CAM40487.1 - 0.048 13.6 0.2 5.8 6.9 0.1 3.0 3 1 0 3 3 3 0 Glycosyl hydrolase family 65, C-terminal domain EF-hand_7 PF13499.6 CAM40489.1 - 6.7e-40 135.4 16.3 4.9e-08 33.3 0.0 6.1 6 1 0 6 6 6 5 EF-hand domain pair EF-hand_1 PF00036.32 CAM40489.1 - 4.6e-36 119.7 15.1 0.00012 21.4 0.0 10.7 11 0 0 11 11 11 7 EF hand EF-hand_6 PF13405.6 CAM40489.1 - 9.1e-34 112.5 11.9 0.00027 20.6 0.0 10.3 10 0 0 10 10 10 7 EF-hand domain EF-hand_5 PF13202.6 CAM40489.1 - 3.6e-30 102.1 11.4 6.1e-05 22.3 0.0 9.3 11 0 0 11 11 11 6 EF hand EF-hand_8 PF13833.6 CAM40489.1 - 7.1e-19 67.4 15.8 0.0015 18.3 0.0 9.9 8 3 1 9 9 9 6 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CAM40489.1 - 1.1e-10 41.9 0.5 0.2 12.0 0.0 5.7 4 2 0 5 5 5 3 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 CAM40489.1 - 0.012 15.5 0.7 13 5.7 0.0 4.3 4 0 0 4 4 4 0 Caleosin related protein EF-hand_13 PF17958.1 CAM40489.1 - 0.013 15.3 0.0 17 5.3 0.1 3.8 2 1 0 2 2 2 0 EF-hand domain SHOCT PF09851.9 CAM40489.1 - 0.032 14.0 0.8 14 5.6 0.0 3.7 3 0 0 3 3 3 0 Short C-terminal domain DUF3349 PF11829.8 CAM40489.1 - 0.041 14.7 0.2 12 6.7 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3349) EF-hand_10 PF14788.6 CAM40489.1 - 0.068 13.0 0.2 13 5.7 0.0 4.4 5 0 0 5 5 5 0 EF hand EF-hand_4 PF12763.7 CAM40489.1 - 6.5 6.8 10.7 8.6 6.4 0.0 5.6 5 1 2 7 7 7 0 Cytoskeletal-regulatory complex EF hand Aquarius_N PF16399.5 CAM40490.1 - 5.4 4.9 5.9 7.8 4.4 5.9 1.1 1 0 0 1 1 1 0 Intron-binding protein aquarius N-terminus PGK PF00162.19 CAM40491.1 - 7.8e-137 456.2 0.1 9.7e-137 455.9 0.1 1.1 1 0 0 1 1 1 1 Phosphoglycerate kinase PAS PF00989.25 CAM40491.1 - 6e-07 29.5 0.0 2e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 CAM40491.1 - 2.8e-05 24.3 0.0 8.5e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 CAM40491.1 - 0.00054 19.9 0.0 0.0019 18.2 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 CAM40491.1 - 0.0022 18.2 0.0 0.0089 16.3 0.0 2.1 2 0 0 2 2 2 1 PAS domain bPH_1 PF08000.11 CAM40491.1 - 0.12 12.5 0.2 0.23 11.5 0.2 1.5 1 0 0 1 1 1 0 Bacterial PH domain CAS_CSE1 PF03378.15 CAM40492.1 - 7.3e-64 215.9 0.0 1.5e-63 214.8 0.0 1.5 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 CAM40492.1 - 5.1e-45 153.9 0.0 7e-45 153.4 0.0 1.2 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 CAM40492.1 - 0.0003 20.6 0.0 0.0048 16.8 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 CAM40492.1 - 0.0051 16.9 0.3 1.7 8.7 0.2 3.6 1 1 0 1 1 1 1 Exportin 1-like protein MCM_N PF14551.6 CAM40492.1 - 0.26 11.9 0.5 6 7.5 0.1 3.0 3 0 0 3 3 3 0 MCM N-terminal domain WD40 PF00400.32 CAM40494.1 - 2.6e-07 31.2 9.7 0.41 11.6 0.4 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat Dynein_heavy PF03028.15 CAM40494.1 - 2.1e-06 27.8 0.0 5.6e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain Tcp11 PF05794.13 CAM40495.2 - 4e-28 98.7 2.3 7.7e-28 97.8 2.3 1.4 1 0 0 1 1 1 1 T-complex protein 11 MKT1_C PF12246.8 CAM40496.1 - 1.1e-16 60.8 0.0 1.6e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 CAM40496.1 - 5.3e-08 33.1 0.0 1.6e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication DNA_ligase_A_M PF01068.21 CAM40497.1 - 2.5e-54 184.0 0.0 4.1e-54 183.3 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 CAM40497.1 - 1.4e-31 110.2 0.0 3e-31 109.1 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 CAM40497.1 - 7.5e-24 84.2 0.1 4.6e-23 81.7 0.0 2.3 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 CAM40497.1 - 3.9e-05 24.0 0.0 7.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 RNA ligase DNA_ligase_OB_2 PF14743.6 CAM40497.1 - 0.25 11.4 2.6 4.7 7.3 0.0 3.1 3 0 0 3 3 3 0 DNA ligase OB-like domain TPR_14 PF13428.6 CAM40499.1 - 4.5e-08 33.3 5.6 0.15 12.9 0.1 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 CAM40499.1 - 5.3e-07 30.2 2.8 0.009 16.6 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CAM40499.1 - 2.3e-05 24.5 0.6 7 7.3 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 CAM40499.1 - 2.5e-05 24.3 6.0 0.0022 18.1 0.3 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CAM40499.1 - 5.5e-05 23.0 5.4 0.012 15.7 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 CAM40499.1 - 0.00022 20.9 0.3 11 6.1 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 CAM40499.1 - 0.00038 20.1 0.8 6.9 6.5 0.0 4.0 4 0 0 4 4 4 1 TPR repeat TTC5_OB PF16669.5 CAM40499.1 - 0.0016 18.1 0.2 0.017 14.8 0.2 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat protein 5 OB fold domain TPR_19 PF14559.6 CAM40499.1 - 0.0024 18.3 3.9 0.043 14.3 0.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CAM40499.1 - 0.026 14.7 0.5 0.083 13.1 0.1 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CAM40499.1 - 0.03 14.5 0.2 5.7 7.4 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.6 CAM40499.1 - 0.077 12.2 0.5 0.23 10.6 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Yippee-Mis18 PF03226.14 CAM40500.1 - 4.1e-11 43.0 0.2 5.4e-11 42.6 0.2 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 CAM40500.1 - 0.0008 19.6 0.2 0.0011 19.2 0.2 1.2 1 0 0 1 1 1 1 C-terminal domain of RIG-I C1_4 PF07975.12 CAM40500.1 - 0.29 11.4 4.3 1.4 9.2 0.1 2.4 2 1 0 2 2 2 0 TFIIH C1-like domain Pkinase PF00069.25 CAM40501.1 - 3.3e-22 79.1 0.0 4.1e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM40501.1 - 1.5e-12 47.4 0.0 1.8e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAM40501.1 - 1.2e-09 37.5 0.0 1.6e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CAM40501.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-MIZ PF02891.20 CAM40503.2 - 1.7e-18 66.1 5.6 3e-18 65.3 5.6 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 CAM40503.2 - 2.3e-07 30.5 1.3 4.6e-07 29.6 1.3 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit NUDE_C PF04880.13 CAM40503.2 - 0.059 13.8 0.3 0.12 12.8 0.3 1.6 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region CYLD_phos_site PF16607.5 CAM40503.2 - 0.1 12.4 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Phosphorylation region of CYLD, unstructured Rtf2 PF04641.12 CAM40503.2 - 0.51 9.7 1.0 0.84 9.0 1.0 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger zf-C3HC4_4 PF15227.6 CAM40503.2 - 0.63 10.3 5.8 1.2 9.4 5.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 CAM40503.2 - 2.5 8.0 7.3 5.1 7.0 7.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) S-AdoMet_synt_C PF02773.16 CAM40504.1 - 6.5e-65 217.3 0.0 1.3e-64 216.3 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 CAM40504.1 - 7.8e-42 142.3 0.0 7.1e-41 139.2 0.0 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 CAM40504.1 - 6.8e-41 139.0 0.3 1.5e-40 137.9 0.3 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Strep_pep PF14404.6 CAM40504.1 - 0.022 15.0 0.0 0.09 13.1 0.0 2.0 2 0 0 2 2 2 0 Ribosomally synthesized peptide in Streptomyces species AdoMet_Synthase PF01941.19 CAM40504.1 - 0.17 10.6 0.6 1.4 7.6 0.1 2.2 1 1 1 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) Rhodanese PF00581.20 CAM40505.1 - 9.9e-06 26.0 0.0 1.7e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain RF-1 PF00472.20 CAM40506.1 - 7.5e-08 32.3 0.3 2.4e-07 30.7 0.1 1.9 2 0 0 2 2 2 1 RF-1 domain Phostensin_N PF13916.6 CAM40506.1 - 0.019 15.3 1.6 7 7.1 0.4 2.6 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal DUF4774 PF15999.5 CAM40506.1 - 0.19 11.6 1.3 0.99 9.3 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4774) MgtE_N PF03448.17 CAM40506.1 - 0.23 12.1 0.7 0.55 10.9 0.7 1.5 1 0 0 1 1 1 0 MgtE intracellular N domain p450 PF00067.22 CAM40507.1 - 1.9e-48 165.4 0.0 2.6e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Mago_nashi PF02792.14 CAM40508.1 - 1.1e-60 203.8 0.1 1.3e-60 203.6 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein zf-CCCH PF00642.24 CAM40509.1 - 3.6e-06 26.7 1.4 8e-06 25.6 1.4 1.6 1 1 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CAM40509.1 - 1.1 9.4 6.3 0.28 11.3 1.1 2.2 2 0 0 2 2 2 0 Zinc finger domain Pkinase PF00069.25 CAM40510.1 - 2.6e-34 118.8 0.1 7.8e-18 64.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM40510.1 - 1.5e-10 40.8 0.0 2.4e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Ribosomal_S11 PF00411.19 CAM40511.1 - 3.3e-47 159.4 1.5 4.1e-47 159.1 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 ATP-synt_DE_N PF02823.16 CAM40512.1 - 7.3e-13 48.2 0.0 1.3e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain SOAR PF16533.5 CAM40513.2 - 0.019 14.9 0.2 0.021 14.8 0.2 1.1 1 0 0 1 1 1 0 STIM1 Orai1-activating region DUF2183 PF09949.9 CAM40513.2 - 0.069 13.5 0.0 0.076 13.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) Cyclin PF08613.11 CAM40515.1 - 9.6e-22 78.1 0.8 1.1e-21 77.9 0.1 1.5 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 CAM40515.1 - 1.2e-06 28.2 0.1 2.1e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain LRR_9 PF14580.6 CAM40516.1 - 1.8e-20 73.2 2.7 2.6e-13 49.9 0.1 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 CAM40516.1 - 4.5e-11 42.8 15.5 1.7e-05 25.1 0.3 3.7 2 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM40516.1 - 1.1e-08 34.7 16.8 7e-06 25.7 4.9 3.4 1 1 3 4 4 4 4 Leucine rich repeat Ribosomal_L15e PF00827.17 CAM40517.1 - 1.8e-85 285.5 8.1 2.1e-85 285.3 8.1 1.0 1 0 0 1 1 1 1 Ribosomal L15 ATP-synt_C PF00137.21 CAM40518.1 - 7.2e-20 71.1 37.0 7.2e-12 45.5 13.6 2.9 3 0 0 3 3 3 2 ATP synthase subunit C SnoaL_2 PF12680.7 CAM40519.1 - 3.9e-05 24.2 0.0 5.1e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 CAM40519.1 - 0.00027 21.2 0.1 0.00071 19.8 0.1 1.7 1 1 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 CAM40519.1 - 0.0037 17.1 0.0 0.0074 16.1 0.0 1.5 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DUF4440 PF14534.6 CAM40519.1 - 0.011 16.1 0.0 0.023 15.1 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4440) RET_CLD3 PF17812.1 CAM40520.1 - 0.2 11.9 1.9 1.9 8.7 0.1 2.6 2 1 0 2 2 2 0 RET Cadherin like domain 3 ABC_tran_CTD PF16326.5 CAM40520.1 - 4.3 7.7 25.3 1.2 9.4 0.5 5.6 4 1 2 6 6 6 0 ABC transporter C-terminal domain DUF3808 PF10300.9 CAM40521.1 - 4.3e-28 98.3 6.8 8.5e-27 94.0 5.3 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_12 PF13424.6 CAM40521.1 - 4.5e-08 33.3 1.7 0.00062 20.0 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CAM40521.1 - 1.7e-07 30.8 2.1 0.051 13.7 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 CAM40521.1 - 0.0031 18.1 0.0 9.4 7.0 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CAM40521.1 - 0.0053 17.5 0.0 27 5.9 0.0 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CAM40521.1 - 0.0055 16.5 2.5 2.6 8.0 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF2225 PF09986.9 CAM40521.1 - 0.032 14.0 5.9 0.11 12.2 1.7 3.0 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_6 PF13174.6 CAM40521.1 - 0.042 14.5 11.6 1.7 9.5 0.3 5.5 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 CAM40521.1 - 0.12 12.1 0.2 38 4.1 0.0 3.5 4 0 0 4 4 4 0 TPR repeat ANAPC3 PF12895.7 CAM40521.1 - 0.25 11.6 8.0 1.2 9.4 0.5 4.7 5 1 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Sporozoite_P67 PF05642.11 CAM40521.1 - 2 6.4 3.6 2.8 5.9 3.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen UPF0016 PF01169.19 CAM40522.1 - 3.3e-21 75.4 10.0 1.4e-17 63.7 1.2 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 SurA_N_3 PF13624.6 CAM40523.1 - 2.3 8.0 9.5 8 6.2 0.6 3.4 3 0 0 3 3 3 0 SurA N-terminal domain CPSF_A PF03178.15 CAM40524.1 - 2e-62 211.4 0.0 3.9e-62 210.4 0.0 1.4 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 CAM40524.1 - 6.7e-08 31.6 0.0 1.6e-07 30.3 0.0 1.6 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Ribosomal_60s PF00428.19 CAM40525.1 - 2.9e-24 85.5 10.2 3.4e-24 85.3 10.2 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein DHC_N1 PF08385.12 CAM40526.1 - 0.15 10.6 0.0 0.19 10.3 0.0 1.0 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 Peptidase_A17 PF05380.13 CAM40527.1 - 0.0005 20.1 0.1 0.017 15.1 0.0 2.3 1 1 1 2 2 2 1 Pao retrotransposon peptidase RVT_1 PF00078.27 CAM40527.1 - 0.00058 19.5 0.0 0.0015 18.1 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_integrase PF00589.22 CAM40528.1 - 2.3e-06 27.5 0.0 1.7e-05 24.7 0.0 2.6 2 0 0 2 2 2 1 Phage integrase family RVT_1 PF00078.27 CAM40528.1 - 0.003 17.1 0.0 0.0081 15.7 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A17 PF05380.13 CAM40528.1 - 0.0053 16.8 0.1 0.057 13.4 0.0 2.4 1 1 1 2 2 2 1 Pao retrotransposon peptidase Peptidase_A17 PF05380.13 CAM40529.2 - 0.0026 17.8 0.1 0.041 13.9 0.0 2.3 1 1 1 2 2 2 1 Pao retrotransposon peptidase RVT_1 PF00078.27 CAM40529.2 - 0.0029 17.2 0.0 0.0069 15.9 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Tau95 PF09734.9 CAM40530.2 - 1.7e-20 74.2 0.0 3.3e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 CAM40530.2 - 0.00027 21.1 0.6 0.076 13.2 0.0 2.9 4 0 0 4 4 4 2 Tau95 Triple barrel domain LysM PF01476.20 CAM40531.1 - 1.3e-08 34.7 0.0 0.0024 17.9 0.0 3.1 3 0 0 3 3 3 2 LysM domain HTH_23 PF13384.6 CAM40531.1 - 0.018 14.8 0.0 3.6 7.5 0.0 3.2 3 0 0 3 3 3 0 Homeodomain-like domain HTH_AsnC-type PF13404.6 CAM40531.1 - 0.019 14.8 0.9 2.4 8.1 0.0 3.1 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain Death PF00531.22 CAM40531.1 - 0.11 12.6 0.1 4.4 7.6 0.0 3.0 3 0 0 3 3 3 0 Death domain DUF3606 PF12244.8 CAM40531.1 - 0.23 11.4 1.5 1.3 9.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3606) Herpes_UL52 PF03121.15 CAM40533.2 - 8.4e-12 44.9 0.2 3e-11 43.1 0.1 2.0 2 0 0 2 2 2 1 Herpesviridae UL52/UL70 DNA primase WD40 PF00400.32 CAM40536.1 - 3.5e-27 94.1 14.2 4.6e-07 30.4 0.5 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM40536.1 - 1.2e-14 54.3 0.3 0.016 15.5 0.0 5.5 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 CAM40536.1 - 0.0023 17.6 0.0 0.011 15.4 0.0 1.9 2 1 0 2 2 2 1 PQQ-like domain Ge1_WD40 PF16529.5 CAM40536.1 - 0.045 12.7 4.6 12 4.7 0.1 3.7 2 2 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CAM40536.1 - 0.051 12.9 0.0 0.35 10.1 0.0 2.0 1 1 0 2 2 2 0 WD40-like domain Frtz PF11768.8 CAM40536.1 - 0.094 11.0 0.0 4.7 5.4 0.0 2.8 2 1 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz WDCP PF15390.6 CAM40536.1 - 0.12 10.8 0.1 0.17 10.2 0.1 1.3 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Sen15 PF09631.10 CAM40536.1 - 0.12 12.7 0.0 0.45 10.8 0.0 1.9 2 0 0 2 2 2 0 Sen15 protein HEAT PF02985.22 CAM40537.1 - 8.5e-05 22.5 3.5 0.25 11.7 0.0 5.1 6 0 0 6 6 6 2 HEAT repeat UVR PF02151.19 CAM40537.1 - 0.0026 17.4 7.6 0.0096 15.6 0.4 2.6 2 0 0 2 2 2 2 UvrB/uvrC motif CLASP_N PF12348.8 CAM40537.1 - 0.083 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 CLASP N terminal RecX PF02631.16 CAM40538.2 - 0.061 13.8 0.8 0.11 13.0 0.8 1.3 1 0 0 1 1 1 0 RecX family Zip PF02535.22 CAM40540.1 - 4e-12 46.0 12.2 3.6e-07 29.7 0.8 3.2 2 1 1 3 3 3 3 ZIP Zinc transporter OppC_N PF12911.7 CAM40540.1 - 0.34 10.9 2.2 1.4 9.0 0.3 2.5 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C YrhC PF14143.6 CAM40540.1 - 3.2 7.9 4.7 15 5.8 0.1 3.1 4 0 0 4 4 4 0 YrhC-like protein CEP19 PF14933.6 CAM40543.2 - 8.5e-54 182.3 0.0 1.2e-53 181.8 0.0 1.2 1 0 0 1 1 1 1 CEP19-like protein Nop PF01798.18 CAM40544.1 - 7.5e-47 159.7 0.0 8.9e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Ank_2 PF12796.7 CAM40545.1 - 1.6e-12 47.9 0.1 9.8e-10 38.9 0.0 2.9 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CAM40545.1 - 3e-07 30.2 1.6 0.0048 17.3 0.2 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 CAM40545.1 - 2.7e-06 27.8 0.0 0.0042 17.6 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CAM40545.1 - 4e-06 27.0 8.2 2.2e-05 24.7 0.7 3.9 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 CAM40545.1 - 4.2e-06 26.9 2.0 0.0026 18.0 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Iwr1 PF08574.10 CAM40546.1 - 2.6e-05 25.2 2.8 2.6e-05 25.2 2.8 2.2 3 0 0 3 3 3 1 Transcription factor Iwr1 TrbC PF04956.13 CAM40547.1 - 0.093 13.0 2.8 5.5 7.3 0.1 3.5 1 1 1 3 3 3 0 TrbC/VIRB2 family Tetraspanin PF00335.20 CAM40548.1 - 9.9e-10 38.5 15.2 1.6e-09 37.8 15.2 1.3 1 0 0 1 1 1 1 Tetraspanin family DUF5367 PF17329.2 CAM40548.1 - 0.065 13.4 0.3 0.065 13.4 0.3 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5367) RIF5_SNase_1 PF18187.1 CAM40549.2 - 1.2e-78 262.3 0.6 3.3e-78 260.9 0.6 1.8 1 0 0 1 1 1 1 TbRIF5 SNase domain 1 RIF5_SNase_2 PF18189.1 CAM40549.2 - 1.9e-68 229.2 0.1 4.8e-68 227.9 0.1 1.8 1 0 0 1 1 1 1 TbRIF5 SNase domain 2 TRAM1 PF08390.11 CAM40549.2 - 0.14 11.8 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 TRAM1-like protein Wzz PF02706.15 CAM40550.2 - 0.023 15.0 0.4 0.064 13.6 0.1 1.9 2 0 0 2 2 2 0 Chain length determinant protein DUF3762 PF12591.8 CAM40550.2 - 0.028 14.6 0.1 0.069 13.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3762) Peptidase_M14 PF00246.24 CAM40551.2 - 4e-11 43.3 0.0 9.1e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 CAM40551.2 - 3e-08 34.0 0.1 1.3e-07 31.9 0.0 2.1 2 0 0 2 2 2 1 Cytosolic carboxypeptidase N-terminal domain PMP1_2 PF08114.11 CAM40552.1 - 0.23 11.3 2.0 0.75 9.6 2.0 1.8 1 0 0 1 1 1 0 ATPase proteolipid family MspA PF09203.11 CAM40553.1 - 0.026 14.4 0.0 0.029 14.2 0.0 1.1 1 0 0 1 1 1 0 MspA pP_pnuc_1 PF18165.1 CAM40553.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Predicted pPIWI-associating nuclease DHHC PF01529.20 CAM40554.1 - 0.00015 21.9 3.3 0.00021 21.4 3.3 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase ClpB_D2-small PF10431.9 CAM40554.1 - 0.15 12.1 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein A_deamin PF02137.18 CAM40555.1 - 1.8e-07 31.0 0.0 2.4e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain RRM_1 PF00076.22 CAM40556.1 - 6.3e-11 41.9 0.1 1.4e-10 40.9 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CAM40556.1 - 0.00085 19.1 0.0 0.0014 18.5 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 CAM40556.1 - 0.0014 18.7 0.0 0.003 17.6 0.0 1.6 1 1 0 1 1 1 1 RNA binding motif DUF2169 PF09937.9 CAM40556.1 - 0.041 13.3 0.0 5.8 6.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2169) Mpv17_PMP22 PF04117.12 CAM40557.1 - 2.5e-07 30.8 2.0 2.7e-07 30.7 0.8 1.6 2 0 0 2 2 2 1 Mpv17 / PMP22 family WD40 PF00400.32 CAM40558.1 - 2.9e-19 69.1 9.5 0.0049 17.7 0.0 7.0 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM40558.1 - 3.7e-06 27.1 0.0 0.99 9.7 0.0 4.6 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain CSTF1_dimer PF16699.5 CAM40558.1 - 0.0041 16.9 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 Cleavage stimulation factor subunit 1, dimerisation domain Cytochrom_D1 PF02239.16 CAM40558.1 - 0.047 12.2 0.0 0.47 8.9 0.0 2.1 2 1 0 2 2 2 0 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 CAM40558.1 - 0.072 12.0 0.0 6.9 5.5 0.0 2.9 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein LAL_C2 PF18603.1 CAM40558.1 - 0.097 12.8 1.7 0.16 12.2 0.3 2.1 2 0 0 2 2 2 0 L-amino acid ligase C-terminal domain 2 PD40 PF07676.12 CAM40558.1 - 0.15 12.1 0.3 26 4.9 0.0 3.2 3 1 0 3 3 3 0 WD40-like Beta Propeller Repeat Sugar_tr PF00083.24 CAM40559.1 - 1.3e-133 446.2 25.2 1.7e-133 445.9 25.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAM40559.1 - 1.5e-15 57.0 22.8 1.5e-15 57.0 22.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily YlmH_RBD PF17774.1 CAM40559.1 - 0.17 12.2 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative RNA-binding domain in YlmH Autophagy_N PF03986.13 CAM40560.1 - 3.6e-26 91.7 0.2 5.5e-26 91.1 0.2 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 CAM40560.1 - 1.8e-19 70.1 2.1 4.2e-19 68.9 2.1 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 CAM40560.1 - 1.2e-10 40.7 0.9 3e-10 39.4 0.9 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal ABC_tran PF00005.27 CAM40562.1 - 4.6e-44 150.3 0.0 1.2e-20 74.4 0.0 3.1 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 CAM40562.1 - 2.1e-16 60.6 1.4 0.00033 20.6 0.0 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CAM40562.1 - 1.5e-10 40.9 2.7 0.00039 19.9 0.0 4.9 3 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CAM40562.1 - 1.2e-07 31.4 0.2 0.012 15.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CAM40562.1 - 1.3e-07 31.7 0.2 0.0089 15.9 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 CAM40562.1 - 0.00028 21.2 0.0 0.41 10.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 CAM40562.1 - 0.00073 19.6 0.0 0.24 11.5 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 CAM40562.1 - 0.0011 19.3 0.0 0.95 9.9 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_23 PF13476.6 CAM40562.1 - 0.0012 19.4 16.9 0.1 13.1 0.1 4.6 5 0 0 5 5 4 2 AAA domain AAA PF00004.29 CAM40562.1 - 0.0015 19.0 0.1 1.9 8.9 0.0 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CAM40562.1 - 0.0016 18.9 4.2 1.6 9.1 0.0 3.5 2 1 1 3 3 3 2 AAA ATPase domain AAA_28 PF13521.6 CAM40562.1 - 0.0017 18.7 3.9 0.099 12.9 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_5 PF07728.14 CAM40562.1 - 0.0033 17.4 0.1 1.7 8.7 0.1 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 CAM40562.1 - 0.0062 16.3 1.4 0.75 9.5 0.0 3.3 2 1 1 3 3 3 1 AAA domain AAA_14 PF13173.6 CAM40562.1 - 0.0071 16.4 0.0 2.7 8.1 0.0 3.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CAM40562.1 - 0.008 16.3 1.5 0.97 9.6 0.0 3.2 4 0 0 4 4 3 1 AAA domain ABC_tran_Xtn PF12848.7 CAM40562.1 - 0.01 15.8 2.4 0.01 15.8 2.4 3.5 3 0 0 3 3 3 0 ABC transporter Rad17 PF03215.15 CAM40562.1 - 0.014 15.3 0.0 4.6 7.1 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain SbcCD_C PF13558.6 CAM40562.1 - 0.014 15.6 0.5 0.73 10.1 0.1 3.6 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Nbl1_Borealin_N PF10444.9 CAM40562.1 - 0.043 13.5 0.2 0.15 11.7 0.2 2.0 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal NTPase_1 PF03266.15 CAM40562.1 - 0.052 13.5 0.1 1.8 8.5 0.0 2.7 3 0 0 3 3 2 0 NTPase Mg_chelatase PF01078.21 CAM40562.1 - 0.074 12.4 0.0 4.8 6.5 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 CAM40562.1 - 0.12 12.3 0.1 11 5.9 0.1 2.6 2 0 0 2 2 2 0 NACHT domain AAA_15 PF13175.6 CAM40562.1 - 0.32 10.7 13.7 0.45 10.2 0.0 4.5 5 1 1 6 6 5 0 AAA ATPase domain Cytidylate_kin PF02224.18 CAM40562.1 - 0.8 9.4 3.9 14 5.4 0.0 3.7 3 1 1 4 4 4 0 Cytidylate kinase AAA_18 PF13238.6 CAM40562.1 - 0.88 10.1 7.7 1.8 9.1 0.0 3.5 4 1 1 5 5 2 0 AAA domain HSP90 PF00183.18 CAM40563.1 - 7.8e-159 529.9 8.3 9.2e-159 529.6 8.3 1.0 1 0 0 1 1 1 1 Hsp90 protein Ribosomal_S20p PF01649.18 CAM40563.1 - 0.0045 17.6 0.4 0.0045 17.6 0.4 2.7 3 1 0 3 3 3 1 Ribosomal protein S20 LOH1CR12 PF10158.9 CAM40563.1 - 0.012 15.6 0.4 0.044 13.8 0.3 2.0 2 0 0 2 2 2 0 Tumour suppressor protein Cofac_haem_bdg PF04187.13 CAM40563.1 - 0.075 13.0 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN FAR1 PF03101.15 CAM40563.1 - 0.45 11.2 4.7 0.41 11.4 1.5 2.4 3 0 0 3 3 3 0 FAR1 DNA-binding domain Lge1 PF11488.8 CAM40563.1 - 4.5 7.5 11.0 6.6 7.0 2.3 3.2 3 0 0 3 3 3 0 Transcriptional regulatory protein LGE1 HSP90 PF00183.18 CAM40564.1 - 5e-226 751.6 23.9 6.3e-226 751.3 23.9 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 CAM40564.1 - 1.1e-17 64.6 0.1 2.2e-17 63.6 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CAM40564.1 - 6.8e-11 42.1 0.1 2.2e-10 40.5 0.1 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_S20p PF01649.18 CAM40564.1 - 0.014 16.0 0.4 0.014 16.0 0.4 4.1 5 0 0 5 5 5 0 Ribosomal protein S20 LOH1CR12 PF10158.9 CAM40564.1 - 0.075 13.1 0.2 0.27 11.3 0.2 1.9 1 0 0 1 1 1 0 Tumour suppressor protein HSP90 PF00183.18 CAM40565.1 - 4.5e-170 567.0 9.5 5.2e-170 566.7 9.5 1.0 1 0 0 1 1 1 1 Hsp90 protein Ribosomal_S20p PF01649.18 CAM40565.1 - 0.0049 17.5 0.4 0.0049 17.5 0.4 2.7 3 1 0 3 3 3 1 Ribosomal protein S20 LOH1CR12 PF10158.9 CAM40565.1 - 0.012 15.6 0.3 0.048 13.7 0.3 2.0 1 0 0 1 1 1 0 Tumour suppressor protein Cofac_haem_bdg PF04187.13 CAM40565.1 - 0.086 12.8 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN FAR1 PF03101.15 CAM40565.1 - 0.39 11.5 4.5 0.44 11.3 1.5 2.4 3 0 0 3 3 3 0 FAR1 DNA-binding domain Lge1 PF11488.8 CAM40565.1 - 5.4 7.3 11.0 7.1 6.9 2.3 3.2 3 0 0 3 3 3 0 Transcriptional regulatory protein LGE1 WD40 PF00400.32 CAM40566.1 - 6.5e-08 33.1 7.2 5.8e-05 23.8 0.0 5.8 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM40566.1 - 0.00012 22.3 0.0 1.8 8.9 0.0 4.0 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain X PF00739.19 CAM40567.1 - 0.077 13.1 0.1 0.15 12.2 0.1 1.5 1 0 0 1 1 1 0 Trans-activation protein X Hydrolase_4 PF12146.8 CAM40569.1 - 3.5e-16 59.2 0.6 2.8e-10 39.9 0.9 2.2 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CAM40569.1 - 2.8e-13 50.1 0.3 5.9e-09 36.0 0.5 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CAM40569.1 - 1.4e-05 25.9 0.3 3e-05 24.8 0.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CAM40569.1 - 1.5e-05 24.6 0.2 0.03 13.8 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 CAM40569.1 - 9.4e-05 22.3 0.0 0.011 15.6 0.0 2.4 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 CAM40569.1 - 0.027 14.1 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) UPF0227 PF05728.12 CAM40569.1 - 0.05 13.5 0.1 8.6 6.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Abhydrolase_3 PF07859.13 CAM40569.1 - 0.064 13.1 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 CAM40569.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) MutS_V PF00488.21 CAM40570.1 - 1.1e-71 240.8 0.0 2.1e-71 239.8 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CAM40570.1 - 1.5e-27 97.1 0.7 1.5e-27 97.1 0.7 1.9 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 CAM40570.1 - 4.9e-16 58.9 1.7 1e-15 57.8 1.7 1.6 1 0 0 1 1 1 1 MutS family domain IV R2K_3 PF14243.6 CAM40570.1 - 0.055 13.5 0.1 0.33 10.9 0.0 2.2 3 0 0 3 3 3 0 ATP-grasp domain, R2K clade family 3 MnmE_helical PF12631.7 CAM40570.1 - 0.061 13.5 0.5 0.17 12.0 0.3 1.8 2 0 0 2 2 2 0 MnmE helical domain AAA_29 PF13555.6 CAM40570.1 - 0.073 12.8 0.1 0.43 10.4 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_13 PF13166.6 CAM40570.1 - 0.29 9.7 5.1 0.032 12.9 0.8 1.5 2 0 0 2 2 2 0 AAA domain FAD_binding_7 PF03441.14 CAM40576.2 - 1.6e-68 230.2 2.4 3.3e-68 229.1 2.3 1.6 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 CAM40576.2 - 2.8e-30 105.5 0.0 5e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase CALM_bind PF16025.5 CAM40577.2 - 0.055 13.9 2.5 0.065 13.7 0.3 2.3 2 0 0 2 2 2 0 Calcium-dependent calmodulin binding SET PF00856.28 CAM40580.1 - 4e-09 37.1 0.0 1e-08 35.8 0.0 1.7 1 0 0 1 1 1 1 SET domain ADH_N PF08240.12 CAM40581.2 - 0.00027 20.8 0.1 0.00042 20.2 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CAM40581.2 - 0.0032 17.4 0.0 0.0045 17.0 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2340 PF10209.9 CAM40581.2 - 0.026 15.0 0.1 0.034 14.6 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2340) ADH_zinc_N_2 PF13602.6 CAM40581.2 - 0.093 13.8 0.0 0.13 13.3 0.0 1.2 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ADH_N PF08240.12 CAM40582.1 - 1.3e-23 82.9 0.0 3.1e-23 81.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CAM40582.1 - 4.5e-17 62.3 0.1 8.9e-17 61.3 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CAM40582.1 - 7.1e-06 27.1 0.0 1.4e-05 26.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CAM40582.1 - 8.5e-05 22.1 0.2 0.00022 20.8 0.2 1.8 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus LRR_4 PF12799.7 CAM40583.2 - 1.8e-24 85.4 0.0 7.1e-05 23.1 0.0 9.6 10 1 1 11 11 11 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM40583.2 - 1e-10 41.2 5.5 0.00035 20.3 0.0 6.8 5 2 1 6 6 6 3 Leucine rich repeat LRR_6 PF13516.6 CAM40583.2 - 0.0074 16.3 3.0 1.3 9.3 0.0 5.4 5 0 0 5 5 5 1 Leucine Rich repeat LRR_1 PF00560.33 CAM40583.2 - 0.24 12.1 7.5 49 5.1 0.1 6.5 6 1 0 6 6 6 0 Leucine Rich Repeat NifU PF01106.17 CAM40585.1 - 1.3e-17 63.7 0.0 3.1e-17 62.5 0.0 1.7 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.11 CAM40585.1 - 5.2e-12 45.7 0.0 7.9e-10 38.7 0.0 2.5 2 0 0 2 2 2 2 Scaffold protein Nfu/NifU N terminal RtcB PF01139.17 CAM40587.1 - 3.6e-96 322.9 0.0 6.4e-96 322.0 0.0 1.4 1 1 0 1 1 1 1 tRNA-splicing ligase RtcB FYVE PF01363.21 CAM40588.1 - 0.44 10.7 19.8 1.8 8.7 19.8 2.0 1 1 0 1 1 1 0 FYVE zinc finger Nkap_C PF06047.11 CAM40590.1 - 6.2e-15 55.2 1.0 6.2e-15 55.2 1.0 2.0 2 0 0 2 2 2 1 NF-kappa-B-activating protein C-terminal domain BRE1 PF08647.11 CAM40592.1 - 1.5e-12 47.4 9.6 1.5e-12 47.4 9.6 11.4 3 2 10 13 13 13 5 BRE1 E3 ubiquitin ligase ATG16 PF08614.11 CAM40592.1 - 0.0022 18.3 18.2 0.0022 18.3 18.2 8.5 1 1 7 8 8 8 3 Autophagy protein 16 (ATG16) DUF3450 PF11932.8 CAM40592.1 - 0.0022 17.3 11.8 0.0022 17.3 11.8 9.6 2 2 6 9 9 9 2 Protein of unknown function (DUF3450) GAS PF13851.6 CAM40592.1 - 0.0073 15.7 5.4 0.0073 15.7 5.4 7.9 2 2 5 7 7 7 2 Growth-arrest specific micro-tubule binding DUF745 PF05335.13 CAM40592.1 - 0.0077 16.0 11.9 0.0077 16.0 11.9 7.9 1 1 9 10 10 10 1 Protein of unknown function (DUF745) DUF4094 PF13334.6 CAM40592.1 - 0.0081 16.6 4.1 0.0081 16.6 4.1 9.2 1 1 4 7 7 7 1 Domain of unknown function (DUF4094) DUF724 PF05266.14 CAM40592.1 - 0.0099 15.7 3.7 0.0099 15.7 3.7 9.0 3 2 7 10 10 10 4 Protein of unknown function (DUF724) AAA_13 PF13166.6 CAM40592.1 - 0.035 12.8 111.8 0.0053 15.5 9.8 6.6 1 1 5 6 6 6 0 AAA domain rve_3 PF13683.6 CAM40592.1 - 0.66 9.8 3.4 7.4 6.4 0.1 4.1 3 0 0 3 3 3 0 Integrase core domain APG6_N PF17675.1 CAM40592.1 - 2.9 8.4 148.8 0.22 12.0 15.4 9.5 2 2 6 9 9 9 0 Apg6 coiled-coil region IGR PF09597.10 CAM40593.1 - 1.8e-05 24.7 0.0 3.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 IGR protein motif TPR_12 PF13424.6 CAM40594.1 - 0.012 15.9 0.3 2.7 8.4 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CAM40594.1 - 0.015 15.4 0.3 8.3 6.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 CAM40594.1 - 0.019 15.0 2.5 2.7 8.2 0.2 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.9 CAM40594.1 - 0.024 14.4 0.3 4.3 7.0 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain TPR_1 PF00515.28 CAM40594.1 - 0.069 13.0 0.0 16 5.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 CAM40594.1 - 0.14 12.1 1.4 4.6 7.2 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat IFT57 PF10498.9 CAM40596.1 - 3.8e-63 213.7 5.2 4.3e-63 213.5 5.2 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 HBM PF16591.5 CAM40596.1 - 9.2e-05 22.0 8.0 9.2e-05 22.0 8.0 1.6 2 0 0 2 2 2 1 Helical bimodular sensor domain mRNA_stabil PF13929.6 CAM40596.1 - 0.00031 19.8 0.8 0.00065 18.8 0.1 1.8 1 1 1 2 2 2 1 mRNA stabilisation TPR_MLP1_2 PF07926.12 CAM40596.1 - 0.0029 17.7 10.0 0.075 13.1 0.5 2.5 2 1 0 2 2 2 2 TPR/MLP1/MLP2-like protein Apolipoprotein PF01442.18 CAM40596.1 - 0.0041 17.0 12.1 0.014 15.2 12.1 2.0 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain CREPT PF16566.5 CAM40596.1 - 0.0049 17.1 5.3 0.0089 16.2 5.3 1.5 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour KxDL PF10241.9 CAM40596.1 - 0.005 17.1 4.4 0.97 9.7 0.3 2.6 2 0 0 2 2 2 2 Uncharacterized conserved protein FRB_dom PF08771.11 CAM40596.1 - 0.01 16.2 0.8 0.025 15.0 0.8 1.7 1 1 0 1 1 1 0 FKBP12-rapamycin binding domain AAA_13 PF13166.6 CAM40596.1 - 0.024 13.3 4.8 0.029 13.0 4.8 1.1 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.11 CAM40596.1 - 0.036 12.9 12.8 0.048 12.5 11.2 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein CHDCT2 PF08074.11 CAM40596.1 - 0.048 13.8 5.0 0.39 10.9 2.1 2.2 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain Laminin_II PF06009.12 CAM40596.1 - 0.064 13.3 10.0 0.51 10.3 0.5 2.4 1 1 1 2 2 2 0 Laminin Domain II Phage_GPO PF05929.11 CAM40596.1 - 0.067 12.8 4.1 0.1 12.2 4.1 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF745 PF05335.13 CAM40596.1 - 0.075 12.8 8.6 0.84 9.3 6.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF1664 PF07889.12 CAM40596.1 - 0.12 12.5 10.5 0.63 10.1 3.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 CAM40596.1 - 0.21 11.1 10.9 0.49 9.9 11.0 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit Fzo_mitofusin PF04799.13 CAM40596.1 - 0.25 10.9 8.5 0.25 10.9 7.1 1.7 1 1 0 1 1 1 0 fzo-like conserved region DUF2203 PF09969.9 CAM40596.1 - 0.8 10.4 6.2 1.6 9.5 4.2 2.4 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) PRKG1_interact PF15898.5 CAM40596.1 - 0.82 10.6 10.9 0.65 10.9 8.6 2.0 2 1 0 2 2 1 0 cGMP-dependent protein kinase interacting domain Ead_Ea22 PF13935.6 CAM40596.1 - 1.1 9.9 6.4 4.4 8.0 6.4 2.3 1 1 0 1 1 1 0 Ead/Ea22-like protein Atg14 PF10186.9 CAM40596.1 - 1.6 7.7 11.9 5.1 6.1 11.5 1.8 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 CAM40596.1 - 8 5.6 7.9 11 5.1 1.0 1.8 1 1 1 2 2 2 0 TMPIT-like protein EF-hand_7 PF13499.6 CAM40598.1 - 0.0025 18.2 0.0 0.0036 17.7 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CAM40598.1 - 0.011 15.2 0.0 0.16 11.6 0.0 2.4 1 1 1 2 2 2 0 EF hand EF-hand_6 PF13405.6 CAM40598.1 - 0.018 15.0 0.0 0.069 13.1 0.0 2.0 1 1 0 1 1 1 0 EF-hand domain HR1 PF02185.16 CAM40599.1 - 0.0025 17.9 1.7 0.0025 17.9 1.7 5.9 5 2 2 7 7 7 1 Hr1 repeat EF1_GNE PF00736.19 CAM40599.1 - 0.53 10.5 5.5 34 4.7 1.8 3.9 3 0 0 3 3 3 0 EF-1 guanine nucleotide exchange domain WD40 PF00400.32 CAM40601.1 - 0.022 15.6 1.0 31 5.7 0.2 4.0 4 0 0 4 4 4 0 WD domain, G-beta repeat FmrO PF07091.11 CAM40601.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) ERG4_ERG24 PF01222.17 CAM40602.1 - 3.4e-108 362.2 24.8 3.9e-108 362.0 24.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family TPR_2 PF07719.17 CAM40604.2 - 0.0058 16.7 4.8 0.7 10.2 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CAM40604.2 - 0.0095 15.7 3.6 0.89 9.5 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CAM40604.2 - 0.0095 16.1 2.1 0.018 15.2 2.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 CAM40604.2 - 0.034 14.7 0.2 0.1 13.1 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat PTR2 PF00854.21 CAM40605.1 - 2.3e-32 112.3 0.9 3.4e-29 101.9 0.0 2.8 2 1 0 2 2 2 2 POT family MFS_1 PF07690.16 CAM40605.1 - 3.1e-07 29.7 36.9 2.7e-05 23.3 15.1 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Herpes_glycop_H PF02489.16 CAM40605.1 - 0.12 10.9 0.1 0.17 10.3 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein H main domain Ribosomal_L6e PF01159.19 CAM40606.2 - 2.2e-28 99.0 0.7 1.5e-27 96.3 0.7 2.0 1 1 0 1 1 1 1 Ribosomal protein L6e KOW PF00467.29 CAM40606.2 - 0.00036 20.4 0.0 0.0015 18.4 0.0 2.1 1 1 1 2 2 2 1 KOW motif ParE-like_toxin PF15781.5 CAM40606.2 - 0.6 10.1 3.1 2.8 8.0 3.1 2.0 1 1 0 1 1 1 0 ParE-like toxin of type II bacterial toxin-antitoxin system OAD_gamma PF04277.13 CAM40606.2 - 4.9 7.8 9.7 0.78 10.4 5.5 1.8 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain WD40 PF00400.32 CAM40607.2 - 6e-16 58.5 6.1 3.2e-05 24.6 0.2 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM40607.2 - 0.00023 21.4 0.0 5.8 7.3 0.0 4.7 2 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain MCCD1 PF15707.5 CAM40608.2 - 0.052 14.0 0.9 0.1 13.1 0.9 1.4 1 0 0 1 1 1 0 Mitochondrial coiled-coil domain protein 1 Rot1 PF10681.9 CAM40608.2 - 0.18 11.3 0.3 0.39 10.2 0.0 1.6 2 0 0 2 2 2 0 Chaperone for protein-folding within the ER, fungal BRF1 PF07741.13 CAM40608.2 - 0.18 12.1 0.7 0.34 11.3 0.7 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Vitelline_membr PF10542.9 CAM40608.2 - 5.1 7.1 7.5 18 5.3 4.9 2.6 2 0 0 2 2 2 0 Vitelline membrane cysteine-rich region DUF2040 PF09745.9 CAM40610.1 - 0.0035 17.4 0.2 0.0067 16.5 0.2 1.4 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 55 (DUF2040) CLZ PF16526.5 CAM40611.1 - 0.29 11.5 0.8 0.63 10.4 0.3 1.8 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Cyclin PF08613.11 CAM40612.1 - 2.4e-29 102.8 0.1 6.5e-29 101.4 0.1 1.8 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CAM40612.1 - 0.0004 20.1 0.1 0.00066 19.4 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain ATP-synt PF00231.19 CAM40613.1 - 2.9e-50 171.5 2.1 3.3e-50 171.4 2.1 1.0 1 0 0 1 1 1 1 ATP synthase Ribosomal_S6e PF01092.19 CAM40614.1 - 3.7e-39 133.6 0.0 7.7e-39 132.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e DnaB_bind PF10410.9 CAM40614.1 - 0.26 11.5 6.6 0.12 12.6 1.8 2.6 3 0 0 3 3 3 0 DnaB-helicase binding domain of primase RdRP_3 PF00998.23 CAM40614.1 - 0.4 9.3 6.2 0.48 9.1 6.2 1.1 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase ATP-synt_C PF00137.21 CAM40615.1 - 1.5e-26 92.5 34.3 3.2e-19 69.0 14.6 2.8 3 0 0 3 3 3 2 ATP synthase subunit C GerA PF03323.13 CAM40615.1 - 0.11 11.0 2.6 2.8 6.3 0.3 2.1 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein DUF4064 PF13273.6 CAM40615.1 - 3.9 7.8 15.4 2 8.7 4.3 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) TctB PF07331.11 CAM40615.1 - 6.1 7.1 15.0 29 4.9 15.0 2.1 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family ATP-synt_C PF00137.21 CAM40616.1 - 1.5e-26 92.5 34.3 3.2e-19 69.0 14.6 2.8 3 0 0 3 3 3 2 ATP synthase subunit C GerA PF03323.13 CAM40616.1 - 0.11 11.0 2.6 2.8 6.3 0.3 2.1 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein DUF4064 PF13273.6 CAM40616.1 - 3.9 7.8 15.4 2 8.7 4.3 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) TctB PF07331.11 CAM40616.1 - 6.1 7.1 15.0 29 4.9 15.0 2.1 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Gaa1 PF04114.14 CAM40617.1 - 2.2e-09 36.9 2.0 2.2e-09 36.9 2.0 2.8 1 1 1 2 2 2 1 Gaa1-like, GPI transamidase component Ribosomal_L37ae PF01780.19 CAM40618.1 - 1.2e-36 124.6 4.5 1.4e-36 124.4 4.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family C1_1 PF00130.22 CAM40618.1 - 0.0026 17.6 2.3 0.0038 17.1 2.3 1.2 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_13 PF17977.1 CAM40618.1 - 0.059 13.5 1.1 0.087 13.0 1.1 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 CAM40618.1 - 0.077 13.0 2.3 0.13 12.3 2.3 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain NOB1_Zn_bind PF08772.11 CAM40618.1 - 0.3 11.3 4.5 2.9 8.1 4.0 2.3 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Proteasome PF00227.26 CAM40619.1 - 5.1e-59 199.0 0.0 6.4e-59 198.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CAM40619.1 - 4.4e-13 48.6 0.0 1e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Pex14_N PF04695.13 CAM40620.2 - 2.4e-22 80.3 0.3 2.4e-22 80.3 0.3 3.6 2 1 2 4 4 4 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Rootletin PF15035.6 CAM40620.2 - 1.6e-06 28.3 0.1 2.4e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Spectrin PF00435.21 CAM40620.2 - 0.0072 16.8 1.0 0.012 16.1 1.0 1.3 1 0 0 1 1 1 1 Spectrin repeat HOOK PF05622.12 CAM40620.2 - 0.021 13.0 4.2 0.029 12.5 4.2 1.1 1 0 0 1 1 1 0 HOOK protein DUF2353 PF09789.9 CAM40620.2 - 0.031 13.6 2.5 0.044 13.1 2.5 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) BLOC1_2 PF10046.9 CAM40620.2 - 0.034 14.4 2.8 0.063 13.6 2.8 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Flagellin_C PF00700.21 CAM40620.2 - 0.041 14.3 1.9 0.084 13.2 1.9 1.5 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region TMCO5 PF14992.6 CAM40620.2 - 0.043 13.4 2.0 0.069 12.7 2.0 1.2 1 0 0 1 1 1 0 TMCO5 family MAD PF05557.13 CAM40620.2 - 0.08 11.3 3.1 0.11 10.8 3.1 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Atg14 PF10186.9 CAM40620.2 - 0.11 11.5 3.6 0.17 10.9 3.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-H PF05837.12 CAM40620.2 - 0.11 12.9 7.3 0.2 12.1 7.3 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) CALCOCO1 PF07888.11 CAM40620.2 - 0.14 11.0 5.5 0.19 10.5 5.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like GAS PF13851.6 CAM40620.2 - 0.19 11.1 5.6 0.3 10.4 5.6 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding GIT_CC PF16559.5 CAM40620.2 - 0.25 11.3 2.5 0.28 11.1 0.6 2.1 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Rab5-bind PF09311.11 CAM40620.2 - 0.25 10.7 4.8 0.42 10.0 4.8 1.2 1 0 0 1 1 1 0 Rabaptin-like protein DUF1192 PF06698.11 CAM40620.2 - 0.43 10.7 4.0 0.66 10.1 2.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) Spc7 PF08317.11 CAM40620.2 - 0.59 9.0 6.2 0.87 8.4 6.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 CAM40620.2 - 1 8.7 5.1 1.7 7.9 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 CAM40620.2 - 4.6 7.1 13.9 0.07 12.9 3.7 2.5 2 1 1 3 3 2 0 Septum formation initiator Rrp15p PF07890.12 CAM40621.2 - 2 8.8 10.8 9.2 6.6 10.8 2.1 1 0 0 1 1 1 0 Rrp15p Tubulin PF00091.25 CAM40622.1 - 8.2e-68 228.5 0.0 1.3e-67 227.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CAM40622.1 - 1.6e-41 141.4 0.1 2.3e-41 140.9 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CAM40622.1 - 5e-05 23.6 0.0 0.00013 22.3 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CAM40622.1 - 0.0055 16.4 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 CAM40622.1 - 0.058 12.6 0.2 0.2 10.8 0.0 1.8 2 0 0 2 2 2 0 Tubulin like Tubulin PF00091.25 CAM40623.1 - 8.2e-68 228.5 0.0 1.3e-67 227.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CAM40623.1 - 1.6e-41 141.4 0.1 2.3e-41 140.9 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CAM40623.1 - 4.8e-05 23.6 0.0 0.00013 22.3 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CAM40623.1 - 0.0055 16.4 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 CAM40623.1 - 0.057 12.6 0.2 0.2 10.8 0.0 1.8 2 0 0 2 2 2 0 Tubulin like Hist_deacetyl PF00850.19 CAM40624.1 - 3.7e-75 253.2 0.1 4.5e-45 154.5 0.1 2.1 2 0 0 2 2 2 2 Histone deacetylase domain SR-25 PF10500.9 CAM40624.1 - 4 7.0 5.0 6.3 6.3 5.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Tubulin_C PF03953.17 CAM40625.1 - 3.7e-42 143.5 0.1 5e-42 143.0 0.1 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 CAM40626.1 - 8.2e-68 228.5 0.0 1.3e-67 227.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CAM40626.1 - 1.6e-41 141.4 0.1 2.3e-41 140.9 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CAM40626.1 - 5e-05 23.6 0.0 0.00013 22.3 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CAM40626.1 - 0.0055 16.4 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 CAM40626.1 - 0.058 12.6 0.2 0.2 10.8 0.0 1.8 2 0 0 2 2 2 0 Tubulin like NIF PF03031.18 CAM40627.2 - 6.7e-20 71.4 0.6 2.4e-17 63.1 0.1 2.5 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase Tubulin PF00091.25 CAM40629.1 - 2.3e-54 184.6 0.0 2.6e-54 184.4 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.9 CAM40629.1 - 1.4e-05 25.4 0.0 1.8e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CAM40629.1 - 0.0022 17.7 0.0 0.0038 16.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 CAM40629.1 - 0.14 11.3 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Tubulin like Tubulin_C PF03953.17 CAM40631.1 - 3.9e-37 127.2 0.1 5.1e-37 126.8 0.1 1.1 1 0 0 1 1 1 1 Tubulin C-terminal domain Oxidored_FMN PF00724.20 CAM40632.1 - 2.4e-73 247.4 0.0 3.6e-73 246.8 0.0 1.3 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 CAM40632.1 - 8.6e-22 77.7 2.3 8e-21 74.5 2.3 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CAM40632.1 - 4.1e-09 36.5 0.2 2e-08 34.3 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CAM40632.1 - 1.1e-07 32.2 3.6 0.0025 18.3 1.3 3.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CAM40632.1 - 2.8e-07 30.1 1.8 0.0056 16.0 0.1 3.0 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CAM40632.1 - 8.8e-07 28.6 1.1 1.5e-06 27.8 1.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CAM40632.1 - 1.5e-06 27.2 2.4 8.6e-06 24.7 0.5 2.4 1 1 1 2 2 2 1 HI0933-like protein K_oxygenase PF13434.6 CAM40632.1 - 2.2e-06 27.1 0.1 0.0039 16.4 0.0 2.4 1 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 CAM40632.1 - 1.7e-05 24.1 1.9 3.5e-05 23.1 1.9 1.5 1 0 0 1 1 1 1 FAD binding domain FMO-like PF00743.19 CAM40632.1 - 6.6e-05 21.5 0.1 3.1 6.1 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like DAO PF01266.24 CAM40632.1 - 7.6e-05 22.4 1.1 7.6e-05 22.4 1.1 3.9 3 1 1 4 4 4 1 FAD dependent oxidoreductase GIDA PF01134.22 CAM40632.1 - 0.00011 21.5 2.7 0.0002 20.6 1.8 1.8 1 1 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 CAM40632.1 - 0.00013 21.9 0.2 0.015 15.2 0.0 2.6 3 0 0 3 3 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 CAM40632.1 - 0.00019 20.8 1.4 0.0025 17.1 0.4 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 CAM40632.1 - 0.00075 19.9 0.6 0.048 14.1 0.1 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.17 CAM40632.1 - 0.0034 16.7 0.4 0.01 15.1 0.2 1.8 2 0 0 2 2 2 1 Thi4 family NAD_Gly3P_dh_N PF01210.23 CAM40632.1 - 0.0061 16.5 0.2 0.14 12.1 0.0 2.4 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Amino_oxidase PF01593.24 CAM40632.1 - 0.011 15.1 0.2 0.02 14.2 0.2 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 CAM40632.1 - 0.042 13.1 0.1 0.099 11.9 0.1 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 CAM40632.1 - 0.048 13.7 4.5 0.44 10.5 0.3 3.1 4 0 0 4 4 4 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 CAM40632.1 - 0.11 11.9 0.0 8.3 5.7 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 CAM40632.1 - 0.12 13.1 0.4 12 6.7 0.0 3.8 4 0 0 4 4 4 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_2 PF03446.15 CAM40632.1 - 0.13 12.4 0.0 2 8.6 0.0 2.6 3 0 0 3 3 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 CAM40632.1 - 0.15 12.4 1.1 22 5.3 0.0 3.2 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Lycopene_cycl PF05834.12 CAM40632.1 - 0.21 10.6 1.6 0.31 10.0 0.3 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein TFR_dimer PF04253.15 CAM40634.2 - 0.081 13.0 0.4 1.6 8.9 0.0 2.3 2 0 0 2 2 2 0 Transferrin receptor-like dimerisation domain End3 PF12761.7 CAM40634.2 - 0.098 12.8 0.8 0.21 11.8 0.2 1.8 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Sulfotransfer_4 PF17784.1 CAM40635.2 - 1.7e-44 152.2 0.0 3.2e-44 151.3 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase domain GAS2 PF02187.17 CAM40635.2 - 0.18 11.9 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 Growth-Arrest-Specific Protein 2 Domain DUF1104 PF06518.11 CAM40636.1 - 4.7 7.7 7.2 23 5.4 3.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) zf-Tim10_DDP PF02953.15 CAM40638.1 - 0.001 18.7 1.3 0.08 12.6 0.2 2.4 2 0 0 2 2 2 2 Tim10/DDP family zinc finger DnaJ PF00226.31 CAM40639.1 - 2.3e-21 75.7 0.5 3.7e-21 75.0 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain Ribosomal_S3_C PF00189.20 CAM40641.1 - 1.4e-19 70.4 1.8 1.4e-19 70.4 1.8 2.2 2 1 1 3 3 3 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 CAM40641.1 - 1.8e-07 30.9 0.3 5e-07 29.5 0.3 1.7 2 0 0 2 2 2 1 KH domain IQ PF00612.27 CAM40642.2 - 0.053 13.3 0.0 0.17 11.7 0.0 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif XRCC4 PF06632.12 CAM40643.1 - 1.6 7.5 6.3 2.7 6.8 6.3 1.3 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 FIBP PF05427.11 CAM40644.2 - 6.6e-06 25.7 0.0 0.014 14.7 0.0 2.9 3 0 0 3 3 3 2 Acidic fibroblast growth factor binding (FIBP) WD40 PF00400.32 CAM40645.1 - 4.6e-07 30.4 4.8 0.013 16.3 0.0 6.3 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM40645.1 - 2.4e-06 27.8 0.2 0.059 13.7 0.0 4.4 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain NAPRTase PF04095.16 CAM40646.1 - 3.5e-73 246.2 0.0 4.5e-73 245.8 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 CAM40646.1 - 3.1e-37 127.7 0.1 5.9e-37 126.8 0.1 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain CCDC106 PF15794.5 CAM40647.1 - 3.9 7.1 11.0 6.8 6.3 11.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Skp1 PF01466.19 CAM40648.1 - 1.4e-07 31.5 0.1 2.1e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Cation_ATPase_C PF00689.21 CAM40650.1 - 2.1e-39 135.1 6.4 2.1e-39 135.1 6.4 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CAM40650.1 - 3.5e-30 104.8 2.4 3.5e-30 104.8 2.4 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CAM40650.1 - 1.4e-10 41.8 0.3 0.066 13.5 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CAM40650.1 - 1.5e-06 27.8 0.0 4.1e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CAM40650.1 - 6.1e-06 26.1 0.4 1.1e-05 25.4 0.4 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CAM40650.1 - 8.8e-06 25.7 0.0 2e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) PSP1 PF04468.12 CAM40651.1 - 7.9e-13 48.5 1.0 2.1e-12 47.2 1.0 1.8 1 1 0 1 1 1 1 PSP1 C-terminal conserved region PPTA PF01239.22 CAM40652.1 - 1.7e-26 91.1 16.7 1.4e-08 34.2 0.4 5.8 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat Exostosin PF03016.15 CAM40652.1 - 0.05 12.8 0.7 0.12 11.5 0.5 1.7 1 1 0 1 1 1 0 Exostosin family OCRE PF17780.1 CAM40653.1 - 0.0002 21.3 7.2 0.00041 20.3 7.2 1.4 1 0 0 1 1 1 1 OCRE domain PPR_long PF17177.4 CAM40654.1 - 0.048 13.0 0.8 0.12 11.7 0.0 2.0 2 1 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP Peptidase_S9 PF00326.21 CAM40655.1 - 0.0018 17.8 0.0 0.0029 17.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Voltage_CLC PF00654.20 CAM40656.1 - 1.3e-93 314.0 31.1 7.4e-93 311.6 27.0 2.2 2 0 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 CAM40656.1 - 4.8e-13 49.3 1.0 7.1e-07 29.6 0.1 2.8 3 0 0 3 3 3 2 CBS domain Gly-zipper_YMGG PF13441.6 CAM40656.1 - 0.38 10.5 6.9 2.5 7.9 0.1 2.7 2 0 0 2 2 2 0 YMGG-like Gly-zipper YEATS PF03366.16 CAM40658.1 - 2.3e-08 33.9 0.0 4.5e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 YEATS family Guanylate_kin PF00625.21 CAM40659.1 - 1.9e-48 164.5 0.0 2.3e-48 164.3 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.6 CAM40659.1 - 1.2e-06 29.1 0.1 2.5e-06 28.1 0.1 1.6 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 CAM40659.1 - 1.7e-06 28.1 0.0 2.8e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 CAM40659.1 - 4.2e-05 23.7 0.0 0.00014 22.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CAM40659.1 - 0.00054 20.2 0.2 0.0021 18.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CAM40659.1 - 0.0011 19.4 0.2 0.28 11.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CAM40659.1 - 0.0027 17.6 0.0 0.005 16.7 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase dNK PF01712.19 CAM40659.1 - 0.0028 17.5 0.0 0.18 11.7 0.0 2.1 2 0 0 2 2 2 1 Deoxynucleoside kinase ADK PF00406.22 CAM40659.1 - 0.0031 17.6 0.3 0.22 11.6 0.1 2.2 2 0 0 2 2 2 1 Adenylate kinase AAA_16 PF13191.6 CAM40659.1 - 0.014 15.8 0.3 0.021 15.2 0.3 1.8 1 1 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.15 CAM40659.1 - 0.048 13.6 0.0 0.07 13.0 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain ABC_tran PF00005.27 CAM40659.1 - 0.071 13.6 0.1 0.17 12.4 0.1 2.0 1 1 0 1 1 1 0 ABC transporter CPT PF07931.12 CAM40659.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein zf-CW PF07496.15 CAM40660.1 - 4.9e-12 45.7 14.2 1.9e-08 34.2 7.8 3.0 2 0 0 2 2 2 2 CW-type Zinc Finger Yippee-Mis18 PF03226.14 CAM40661.1 - 0.0033 17.6 1.7 2.5 8.3 0.4 2.7 2 0 0 2 2 2 2 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Nup88 PF10168.9 CAM40661.1 - 0.19 9.5 10.6 0.26 9.0 10.6 1.1 1 0 0 1 1 1 0 Nuclear pore component RIG-I_C-RD PF11648.8 CAM40661.1 - 2.5 8.4 4.5 2.1 8.6 0.0 2.5 2 0 0 2 2 2 0 C-terminal domain of RIG-I DUF16 PF01519.16 CAM40661.1 - 7.4 7.1 14.0 40 4.8 14.1 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF3395 PF11875.8 CAM40662.1 - 0.036 13.9 0.1 0.036 13.9 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3395) TIG PF01833.24 CAM40664.1 - 0.0004 20.4 0.4 0.016 15.2 0.1 2.4 2 0 0 2 2 2 2 IPT/TIG domain TIG PF01833.24 CAM40665.2 - 0.00017 21.6 6.5 0.038 14.1 0.1 3.5 3 0 0 3 3 3 2 IPT/TIG domain FMN_bind PF04205.14 CAM40665.2 - 0.28 11.8 2.3 23 5.6 0.3 2.9 2 1 0 2 2 2 0 FMN-binding domain PUF PF00806.19 CAM40666.1 - 1.5e-50 166.1 6.5 3.3e-06 26.5 0.6 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat sCache_2 PF17200.4 CAM40666.1 - 0.062 13.2 0.0 51 3.7 0.0 3.8 4 0 0 4 4 4 0 Single Cache domain 2 Ax_dynein_light PF10211.9 CAM40669.2 - 2e-39 135.5 8.1 3e-39 134.9 8.1 1.3 1 0 0 1 1 1 1 Axonemal dynein light chain AAA PF00004.29 CAM40671.1 - 4e-15 56.4 0.1 2.1e-10 41.1 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CAM40671.1 - 5.5e-06 26.4 0.0 1.9e-05 24.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CAM40671.1 - 3.8e-05 24.1 1.1 0.00013 22.4 0.1 2.4 3 1 0 3 3 2 1 AAA ATPase domain AAA_18 PF13238.6 CAM40671.1 - 0.00043 20.8 0.0 0.0013 19.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CAM40671.1 - 0.0023 18.2 0.1 0.019 15.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 CAM40671.1 - 0.0031 17.3 0.1 0.0086 15.8 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 CAM40671.1 - 0.0052 16.4 0.0 0.021 14.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CAM40671.1 - 0.0052 16.5 0.0 0.0093 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CAM40671.1 - 0.0058 16.8 0.0 0.02 15.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CAM40671.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 CAM40671.1 - 0.02 14.3 0.0 0.1 11.9 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_11 PF13086.6 CAM40671.1 - 0.026 14.3 0.4 0.11 12.3 0.4 1.9 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CAM40671.1 - 0.033 13.6 0.0 0.093 12.1 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 CAM40671.1 - 0.064 12.4 0.0 0.15 11.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_19 PF13245.6 CAM40671.1 - 0.065 13.6 0.1 0.28 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CAM40671.1 - 0.075 13.3 0.1 0.23 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CAM40671.1 - 0.087 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 CAM40671.1 - 0.089 13.2 0.0 0.29 11.5 0.0 1.9 2 0 0 2 2 1 0 RNA helicase NB-ARC PF00931.22 CAM40671.1 - 0.097 11.8 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 CAM40671.1 - 0.18 11.5 3.1 0.19 11.4 0.0 2.4 3 0 0 3 3 3 0 AAA domain PPR_2 PF13041.6 CAM40672.2 - 4.6e-05 23.5 0.2 0.0002 21.5 0.0 2.2 3 0 0 3 3 3 1 PPR repeat family PPR PF01535.20 CAM40672.2 - 0.0018 18.4 0.1 1.9 8.9 0.0 3.5 3 0 0 3 3 3 1 PPR repeat TPR_19 PF14559.6 CAM40672.2 - 0.018 15.6 0.2 0.12 12.9 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_3 PF13812.6 CAM40672.2 - 0.08 13.0 0.1 0.4 10.8 0.0 2.0 2 0 0 2 2 2 0 Pentatricopeptide repeat domain Effector_1 PF04518.12 CAM40672.2 - 0.081 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Effector from type III secretion system Nucleic_acid_bd PF13820.6 CAM40672.2 - 0.11 12.3 0.1 1.4 8.7 0.1 2.3 1 1 1 2 2 2 0 Putative nucleic acid-binding region GcrA PF07750.11 CAM40673.2 - 0.005 17.3 0.9 0.026 14.9 0.0 2.2 2 0 0 2 2 2 1 GcrA cell cycle regulator F-box PF00646.33 CAM40673.2 - 0.038 13.9 0.1 0.093 12.6 0.1 1.7 1 0 0 1 1 1 0 F-box domain UIM PF02809.20 CAM40673.2 - 0.08 12.9 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin interaction motif WD40 PF00400.32 CAM40674.1 - 4.3e-08 33.7 17.4 1.5e-07 31.9 0.1 5.4 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM40674.1 - 1.5e-05 25.2 0.7 1.5 9.2 0.0 4.1 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 CAM40674.1 - 0.012 16.1 1.6 4.9 7.8 0.0 3.9 2 1 1 3 3 3 0 PQQ-like domain Atg14 PF10186.9 CAM40674.1 - 0.32 10.0 0.7 8.6 5.3 0.4 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 PQQ_2 PF13360.6 CAM40674.1 - 0.54 9.8 5.4 1 8.9 1.6 2.5 1 1 1 2 2 2 0 PQQ-like domain SlyX PF04102.12 CAM40674.1 - 2.3 8.9 4.9 3.2 8.5 1.6 2.5 2 1 0 2 2 2 0 SlyX WD40 PF00400.32 CAM40675.2 - 1.7e-07 31.8 13.2 9.6e-05 23.1 0.6 5.8 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM40675.2 - 2.8e-05 24.3 0.1 5.7 7.3 0.0 3.8 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain COG2 PF06148.11 CAM40675.2 - 0.2 11.7 1.8 0.28 11.3 0.4 1.8 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4226 PF10774.9 CAM40675.2 - 0.87 9.9 5.6 4.5 7.6 0.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4226) HrpB7 PF09486.10 CAM40675.2 - 1.8 9.0 10.6 8 6.8 10.7 2.0 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) CFC PF09443.10 CAM40677.1 - 0.039 13.8 0.1 0.071 13.0 0.1 1.4 1 0 0 1 1 1 0 Cripto_Frl-1_Cryptic (CFC) EAR PF07897.11 CAM40679.1 - 0.096 12.3 0.2 0.19 11.4 0.2 1.5 1 0 0 1 1 1 0 Ethylene-responsive binding factor-associated repression Thioredoxin PF00085.20 CAM40680.1 - 1.9e-08 34.2 0.2 2.9e-08 33.6 0.2 1.3 1 0 0 1 1 1 1 Thioredoxin YfmQ PF10787.9 CAM40680.1 - 0.0055 16.5 0.1 0.0076 16.0 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised protein from bacillus cereus group Thioredoxin_8 PF13905.6 CAM40680.1 - 0.0072 16.6 0.8 0.1 13.0 0.1 2.4 2 1 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 CAM40680.1 - 0.015 15.2 0.1 0.021 14.8 0.1 1.3 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_2 PF13098.6 CAM40680.1 - 0.03 14.8 0.5 0.078 13.4 0.2 1.8 1 1 1 2 2 2 0 Thioredoxin-like domain Ribosomal_L29 PF00831.23 CAM40680.1 - 0.12 12.3 3.3 7.5 6.6 0.1 2.5 2 0 0 2 2 2 0 Ribosomal L29 protein MFS_1_like PF12832.7 CAM40681.1 - 3.9e-47 160.9 25.3 1.1e-46 159.4 25.3 1.7 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 CAM40681.1 - 4.7e-21 75.1 53.6 6.6e-15 54.9 33.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 CAM40681.1 - 2.2e-10 40.1 22.4 4e-10 39.3 22.4 1.4 1 1 0 1 1 1 1 Nucleoside H+ symporter LacY_symp PF01306.19 CAM40681.1 - 1e-05 24.5 19.1 5.1e-05 22.2 19.1 2.0 1 1 0 1 1 1 1 LacY proton/sugar symporter ABC1 PF03109.16 CAM40682.1 - 4.7e-28 97.7 0.0 9.5e-28 96.8 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 CAM40682.1 - 0.00042 20.0 0.0 0.00095 18.8 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CAM40682.1 - 0.031 14.2 0.8 2.4 8.0 0.1 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase PF00069.25 CAM40682.1 - 0.05 13.0 0.0 0.13 11.6 0.0 1.6 1 1 0 1 1 1 0 Protein kinase domain WaaY PF06176.11 CAM40682.1 - 0.069 12.8 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Cwf_Cwc_15 PF04889.12 CAM40683.1 - 3e-05 23.9 15.5 5.2e-05 23.1 15.4 1.4 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DASH_Spc19 PF08287.11 CAM40683.1 - 0.78 9.6 9.1 0.12 12.3 5.0 1.7 2 1 0 2 2 2 0 Spc19 ABC1 PF03109.16 CAM40685.2 - 2.4e-10 40.6 0.0 3.3e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 ABC1 family Aminotran_1_2 PF00155.21 CAM40690.1 - 1e-50 172.9 0.0 1.2e-50 172.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CAM40690.1 - 3e-06 26.0 0.1 4.5e-06 25.4 0.1 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 CAM40690.1 - 2.3e-05 23.6 0.1 4.7e-05 22.5 0.1 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CAM40690.1 - 0.00019 20.8 0.1 0.00028 20.3 0.1 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Corona_NS2 PF04753.12 CAM40690.1 - 0.16 12.6 0.7 0.69 10.5 0.6 2.1 2 0 0 2 2 2 0 Coronavirus non-structural protein NS2 Syntaxin PF00804.25 CAM40691.1 - 5.4e-09 36.0 14.9 8.4e-09 35.4 14.9 1.3 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 CAM40691.1 - 6.3e-06 26.1 0.1 1.5e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 CAM40691.1 - 0.051 14.0 9.9 0.035 14.5 3.0 2.3 2 0 0 2 2 2 0 Syntaxin-like protein ESAG1 PF03238.13 CAM40691.1 - 0.079 12.4 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 ESAG protein MCPsignal PF00015.21 CAM40691.1 - 0.16 11.8 5.7 0.13 12.1 0.6 2.2 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain TBCC_N PF16752.5 CAM40691.1 - 1.6 9.2 14.0 0.31 11.5 4.5 2.9 1 1 2 3 3 3 0 Tubulin-specific chaperone C N-terminal domain DUF1664 PF07889.12 CAM40691.1 - 3.3 7.8 8.5 0.76 9.8 1.3 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF2203 PF09969.9 CAM40691.1 - 7.4 7.3 9.9 45 4.8 4.5 3.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) UPF0113 PF03657.13 CAM40692.1 - 1.1e-18 67.2 0.0 2.8e-18 66.0 0.0 1.6 2 0 0 2 2 2 1 UPF0113 PUA domain UPF0113_N PF17833.1 CAM40692.1 - 3.4e-18 66.0 0.1 5.4e-18 65.3 0.1 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain DUF5317 PF17248.2 CAM40692.1 - 0.064 13.3 0.0 0.1 12.6 0.0 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5317) Baculo_LEF-11 PF06385.12 CAM40692.1 - 0.13 12.8 0.1 0.4 11.2 0.0 1.8 2 0 0 2 2 2 0 Baculovirus LEF-11 protein Complex1_LYR PF05347.15 CAM40693.1 - 5.2e-07 29.6 0.5 8.5e-07 28.9 0.5 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Suppressor_APC PF11414.8 CAM40694.2 - 0.83 9.8 4.0 3.1 7.9 0.1 2.9 2 1 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein Pkinase PF00069.25 CAM40695.1 - 3.2e-64 216.8 0.0 4.3e-64 216.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM40695.1 - 5e-32 111.2 0.0 6.4e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CAM40695.1 - 9.3e-07 28.4 0.3 1.8e-06 27.4 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CAM40695.1 - 0.00027 20.0 0.4 0.00027 20.0 0.4 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 CAM40695.1 - 0.0014 18.0 0.0 0.0023 17.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CAM40695.1 - 0.005 15.7 0.7 0.013 14.4 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 CAM40695.1 - 0.026 14.2 0.3 0.074 12.7 0.0 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 MRP-L28 PF09812.9 CAM40696.1 - 0.0002 21.6 0.2 0.00035 20.7 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Pkinase PF00069.25 CAM40697.2 - 1.1e-48 165.9 0.0 4.7e-27 95.0 0.0 3.4 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CAM40697.2 - 1.1e-27 97.0 0.2 3.1e-19 69.3 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase FHA PF00498.26 CAM40697.2 - 5.6e-11 42.6 0.1 0.00028 21.2 0.0 3.0 2 0 0 2 2 2 2 FHA domain Kinase-like PF14531.6 CAM40697.2 - 1.7e-05 24.3 0.1 0.0011 18.3 0.1 2.2 2 0 0 2 2 2 1 Kinase-like Yop-YscD_cpl PF16697.5 CAM40697.2 - 3.1e-05 24.2 0.1 0.0004 20.6 0.0 2.4 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain RIO1 PF01163.22 CAM40697.2 - 0.0013 18.4 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CAM40697.2 - 0.014 15.3 0.0 0.18 11.7 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family WD40 PF00400.32 CAM40698.2 - 4e-17 62.3 14.6 0.0007 20.4 0.2 6.6 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.8 CAM40698.2 - 0.00078 18.2 3.7 0.25 10.0 0.1 3.3 2 1 2 4 4 4 2 Nucleoporin Nup120/160 TMF_TATA_bd PF12325.8 CAM40698.2 - 0.0095 16.1 4.4 0.0095 16.1 4.4 3.1 1 1 2 3 3 3 1 TATA element modulatory factor 1 TATA binding AAA_13 PF13166.6 CAM40698.2 - 0.027 13.2 14.6 0.0062 15.2 10.9 1.6 1 1 1 2 2 2 0 AAA domain PQQ_3 PF13570.6 CAM40698.2 - 0.067 13.7 0.0 0.73 10.4 0.0 2.7 2 0 0 2 2 2 0 PQQ-like domain OmpH PF03938.14 CAM40698.2 - 0.086 13.2 25.9 0.055 13.8 9.3 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Nucleoporin_N PF08801.11 CAM40698.2 - 0.11 11.2 0.1 1 8.0 0.1 2.3 1 1 0 1 1 1 0 Nup133 N terminal like ATG16 PF08614.11 CAM40698.2 - 0.14 12.4 30.6 0.33 11.2 26.0 2.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4457 PF14652.6 CAM40698.2 - 0.18 11.0 0.3 0.52 9.5 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4457) FUSC PF04632.12 CAM40698.2 - 0.19 10.3 16.6 0.3 9.5 16.6 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family TPR_MLP1_2 PF07926.12 CAM40698.2 - 0.87 9.6 27.4 0.35 10.9 11.8 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein JIP_LZII PF16471.5 CAM40698.2 - 0.99 9.6 16.1 0.77 10.0 4.1 3.2 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II BLOC1_2 PF10046.9 CAM40698.2 - 1.4 9.3 11.5 0.14 12.5 3.2 2.6 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 CAM40698.2 - 2.5 6.9 23.8 12 4.7 23.2 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein Cep57_MT_bd PF06657.13 CAM40698.2 - 3.5 8.2 19.0 0.88 10.1 4.0 3.0 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Tox-ODYAM1 PF15642.6 CAM40698.2 - 3.6 6.5 10.0 3.6 6.5 8.9 1.4 1 1 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Sigma70_ner PF04546.13 CAM40698.2 - 7.1 6.5 14.8 11 5.9 14.8 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Aa_trans PF01490.18 CAM40699.1 - 6.5e-54 183.2 22.2 7.5e-54 183.0 22.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CAM40699.1 - 1e-07 31.4 13.3 1e-07 31.4 13.3 2.9 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family RRM_1 PF00076.22 CAM40701.1 - 5e-08 32.6 0.0 7.3e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 CAM40702.1 - 1.8e-12 46.9 0.1 2.7e-08 33.5 0.1 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CAM40702.1 - 0.0001 21.9 0.1 0.00018 21.1 0.1 1.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAM40702.1 - 0.0037 17.3 0.0 0.0066 16.5 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif DAO_C PF16901.5 CAM40702.1 - 0.018 14.9 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain of alpha-glycerophosphate oxidase Lipase_3 PF01764.25 CAM40703.1 - 4.5e-39 133.6 0.0 6.5e-39 133.0 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CAM40703.1 - 2.3e-05 25.1 0.0 3.3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 CAM40703.1 - 0.00012 21.7 0.2 0.0028 17.3 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 CAM40703.1 - 0.0004 19.7 0.0 0.00062 19.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 CAM40703.1 - 0.0091 15.7 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 CAM40703.1 - 0.032 14.3 0.0 0.052 13.7 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Cutinase PF01083.22 CAM40703.1 - 0.072 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Cutinase Abhydrolase_5 PF12695.7 CAM40703.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family RRM_1 PF00076.22 CAM40704.1 - 2.5e-16 59.2 0.0 3.8e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAM40704.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.4 1 1 0 1 1 1 0 RNA recognition motif TPR_12 PF13424.6 CAM40705.1 - 4e-05 23.8 1.2 4e-05 23.8 1.2 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 CAM40705.1 - 0.0049 16.9 17.7 0.49 10.6 0.2 7.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 CAM40705.1 - 0.018 14.9 11.1 1.9 8.4 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 CAM40705.1 - 0.025 14.6 1.6 11 6.3 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat ubiquitin PF00240.23 CAM40706.1 - 0.0037 17.0 0.1 0.91 9.3 0.1 2.8 2 1 0 2 2 2 2 Ubiquitin family TPR_14 PF13428.6 CAM40707.1 - 0.00069 20.2 1.6 1.3 10.1 0.0 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat BAG6 PF12057.8 CAM40707.1 - 0.09 12.5 0.1 0.45 10.2 0.0 2.0 2 0 0 2 2 2 0 BCL2-associated athanogene 6 PH_12 PF16457.5 CAM40707.1 - 0.19 12.2 0.1 0.19 12.2 0.1 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain PRA1 PF03208.19 CAM40708.1 - 1.4e-17 63.6 4.4 1.4e-17 63.6 4.4 1.5 1 1 0 1 1 1 1 PRA1 family protein TcpE PF12648.7 CAM40708.1 - 0.21 12.1 9.0 0.35 11.4 1.2 2.4 1 1 1 2 2 2 0 TcpE family PRA1 PF03208.19 CAM40709.1 - 4e-26 91.4 6.6 5.9e-26 90.8 6.6 1.2 1 0 0 1 1 1 1 PRA1 family protein GST_C PF00043.25 CAM40710.1 - 2.3e-14 53.4 0.0 3.6e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CAM40710.1 - 5.9e-09 36.2 0.0 1e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CAM40710.1 - 8.2e-07 29.1 0.0 1.2e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CAM40710.1 - 3.5e-06 26.9 0.0 8.8e-06 25.7 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CAM40710.1 - 0.0011 19.3 0.0 0.0022 18.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF1204 PF06721.11 CAM40710.1 - 0.053 13.0 0.0 0.07 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) Fzo_mitofusin PF04799.13 CAM40711.1 - 0.049 13.2 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 fzo-like conserved region ABC_tran_Xtn PF12848.7 CAM40711.1 - 0.059 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter FlgN PF05130.12 CAM40711.1 - 0.065 13.7 0.5 0.97 9.9 0.1 2.3 2 0 0 2 2 2 0 FlgN protein TauE PF01925.19 CAM40712.2 - 4e-12 46.3 19.5 4.7e-06 26.4 8.8 2.2 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE DivIC PF04977.15 CAM40712.2 - 0.006 16.3 0.1 0.016 15.0 0.1 1.7 1 0 0 1 1 1 1 Septum formation initiator DUF2244 PF10003.9 CAM40712.2 - 0.014 15.1 0.5 0.014 15.1 0.5 2.8 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) DUF4131 PF13567.6 CAM40712.2 - 0.15 11.7 1.6 4.6 6.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) CcmD PF04995.14 CAM40712.2 - 0.74 9.9 3.9 8.3 6.6 0.0 2.9 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) LapA_dom PF06305.11 CAM40712.2 - 1.4 8.8 6.9 1.8 8.5 0.3 3.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain RseC_MucC PF04246.12 CAM40712.2 - 3.1 7.7 10.2 0.17 11.9 0.7 2.8 2 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Ribul_P_3_epim PF00834.19 CAM40713.1 - 1.3e-56 191.1 0.0 1.6e-56 190.9 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.24 CAM40713.1 - 0.0032 17.1 0.3 0.0093 15.6 0.3 1.9 2 1 0 2 2 2 1 Orotidine 5'-phosphate decarboxylase / HUMPS family adh_short PF00106.25 CAM40713.1 - 0.11 11.9 0.8 0.24 10.8 0.3 1.7 2 0 0 2 2 2 0 short chain dehydrogenase adh_short_C2 PF13561.6 CAM40713.1 - 0.12 11.9 1.4 0.76 9.3 1.1 2.3 3 0 0 3 3 3 0 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CAM40716.1 - 2.7e-31 108.6 0.0 3.5e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CAM40716.1 - 1.5e-22 80.3 0.0 2.1e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CAM40716.1 - 7e-08 32.6 0.0 1e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CAM40716.1 - 0.029 13.8 0.1 0.05 13.1 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 CAM40716.1 - 0.04 13.8 0.0 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HHH_5 PF14520.6 CAM40716.1 - 0.16 12.6 0.1 0.36 11.5 0.1 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain Peptidase_M20 PF01546.28 CAM40718.1 - 3.9e-18 65.9 0.0 5.6e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CAM40718.1 - 9.3e-08 32.0 0.0 1.6e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain HEAT PF02985.22 CAM40719.1 - 2.9e-09 36.4 12.8 9.9 6.7 0.1 9.9 10 0 0 10 10 10 4 HEAT repeat HEAT_2 PF13646.6 CAM40719.1 - 2.6e-05 24.5 0.0 0.46 10.9 0.0 4.5 2 1 1 3 3 3 2 HEAT repeats Cnd1 PF12717.7 CAM40719.1 - 0.0014 18.7 5.9 3.5 7.7 0.0 4.7 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 CAM40719.1 - 0.012 15.2 3.3 0.19 11.2 0.8 3.8 4 1 0 4 4 4 0 CLASP N terminal Vac14_Fab1_bd PF12755.7 CAM40719.1 - 0.017 15.7 2.5 1.1 9.9 0.1 4.2 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region Nipped-B_C PF12830.7 CAM40719.1 - 0.047 13.6 0.8 8.8 6.2 0.0 3.3 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus Pro_isomerase PF00160.21 CAM40720.1 - 4.4e-45 153.8 0.0 5.1e-45 153.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PHM7_cyt PF14703.6 CAM40721.1 - 0.0091 16.2 0.3 0.011 15.9 0.3 1.1 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PIGA PF08288.12 CAM40724.1 - 2.8e-38 130.4 0.0 5.5e-38 129.5 0.0 1.5 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 CAM40724.1 - 2.6e-28 99.1 0.4 5.5e-28 98.1 0.4 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 CAM40724.1 - 1e-26 93.5 0.0 1.6e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CAM40724.1 - 1.2e-22 80.7 0.0 1.9e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CAM40724.1 - 4.5e-13 50.0 0.0 9.6e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 CAM40724.1 - 0.0018 18.3 0.0 0.016 15.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase 4-like Glyco_trans_2_3 PF13632.6 CAM40724.1 - 0.063 13.2 0.5 0.063 13.2 0.5 1.8 2 0 0 2 2 2 0 Glycosyl transferase family group 2 Glyco_trans_1_2 PF13524.6 CAM40724.1 - 0.15 12.4 0.0 0.39 11.1 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 ThiI PF02568.14 CAM40725.1 - 2.2e-45 154.7 0.1 3.6e-45 154.0 0.1 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Aminotran_5 PF00266.19 CAM40725.1 - 4.1e-26 91.8 0.5 1e-12 47.7 0.0 2.2 1 1 1 2 2 2 2 Aminotransferase class-V tRNA_Me_trans PF03054.16 CAM40725.1 - 8.7e-05 21.5 0.0 0.00016 20.6 0.0 1.4 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.13 CAM40725.1 - 0.0024 17.4 0.6 0.039 13.4 0.0 2.6 3 0 0 3 3 3 1 Queuosine biosynthesis protein QueC DNA_pol_B PF00136.21 CAM40726.1 - 2.2e-137 458.5 0.0 3.1e-137 458.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CAM40726.1 - 2.2e-73 247.4 0.0 4.2e-73 246.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 CAM40726.1 - 6.5e-18 65.0 9.1 1.6e-17 63.7 9.1 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta zinc-ribbons_6 PF07191.12 CAM40726.1 - 0.027 14.4 6.2 0.21 11.6 0.3 2.6 2 0 0 2 2 2 0 zinc-ribbons DNA_pol_B_2 PF03175.13 CAM40726.1 - 0.062 12.1 0.1 0.47 9.3 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral zf-ACC PF17848.1 CAM40726.1 - 8.5 6.5 6.4 2 8.5 0.2 2.6 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain SNF2_N PF00176.23 CAM40727.1 - 5.1e-70 235.9 0.9 2.6e-69 233.6 0.1 2.5 3 1 1 4 4 4 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CAM40727.1 - 5.2e-20 71.9 0.0 2.7e-19 69.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAM40727.1 - 5.4e-09 36.3 0.0 1.6e-08 34.7 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SLIDE PF09111.10 CAM40727.1 - 2.9e-07 30.5 1.0 7e-07 29.3 1.0 1.7 1 0 0 1 1 1 1 SLIDE HAND PF09110.11 CAM40727.1 - 1.1e-05 26.1 3.8 4.3e-05 24.2 3.8 2.1 1 0 0 1 1 1 1 HAND DEAD PF00270.29 CAM40727.1 - 0.0001 22.1 0.0 0.00042 20.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase RRM_occluded PF16842.5 CAM40727.1 - 0.1 12.5 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif Pkinase PF00069.25 CAM40728.1 - 1.7e-67 227.6 0.1 3.8e-67 226.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM40728.1 - 2e-40 138.7 0.1 3.3e-40 138.0 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 CAM40728.1 - 7e-16 58.4 0.7 2.9e-08 34.0 0.2 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CAM40728.1 - 3.7e-11 42.0 0.7 0.01 15.7 0.0 5.4 3 1 1 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 CAM40728.1 - 4.5e-11 41.5 0.7 0.091 12.4 0.1 4.6 5 0 0 5 5 5 3 EF hand Kinase-like PF14531.6 CAM40728.1 - 1.9e-10 40.5 0.0 8.6e-10 38.4 0.0 1.9 1 1 1 2 2 2 1 Kinase-like EF-hand_8 PF13833.6 CAM40728.1 - 3.7e-08 33.1 1.7 0.00032 20.5 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain pair RIO1 PF01163.22 CAM40728.1 - 1.4e-05 24.8 1.7 3.1e-05 23.7 1.7 1.5 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 CAM40728.1 - 0.00079 18.5 0.1 0.0012 17.8 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 CAM40728.1 - 0.0011 18.6 0.4 0.0021 17.6 0.4 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL EF-hand_5 PF13202.6 CAM40728.1 - 0.0027 17.1 0.4 4 7.1 0.0 3.8 3 0 0 3 3 3 1 EF hand Kdo PF06293.14 CAM40728.1 - 0.0033 16.8 0.2 0.0069 15.8 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Crystallin PF00525.18 CAM40728.1 - 0.089 13.0 0.1 0.22 11.7 0.1 1.7 1 0 0 1 1 1 0 Alpha crystallin A chain, N terminal MYO10_CC PF16735.5 CAM40728.1 - 0.12 12.5 0.2 0.37 10.9 0.2 1.8 1 0 0 1 1 1 0 Unconventional myosin-X coiled coil domain TPR_12 PF13424.6 CAM40729.1 - 1.3e-21 76.7 10.5 6e-10 39.3 0.5 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CAM40729.1 - 3.6e-12 45.6 8.6 0.033 14.0 0.2 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 CAM40729.1 - 4.8e-07 29.4 13.1 0.26 11.5 0.4 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 CAM40729.1 - 1.1e-06 28.3 2.7 0.98 9.8 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC5 PF12862.7 CAM40729.1 - 4.6e-05 23.4 4.4 0.14 12.3 0.1 3.1 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 5 TPR_9 PF13371.6 CAM40729.1 - 0.00021 21.3 4.4 0.39 10.9 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 CAM40729.1 - 0.00021 20.8 2.8 0.00021 20.8 2.8 2.2 2 1 0 2 2 2 1 MalT-like TPR region TPR_7 PF13176.6 CAM40729.1 - 0.0026 17.7 8.9 4.6 7.5 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat RPN7 PF10602.9 CAM40729.1 - 0.023 14.4 2.1 3.6 7.3 0.1 3.2 1 1 0 2 2 2 0 26S proteasome subunit RPN7 TPR_21 PF09976.9 CAM40729.1 - 0.036 13.8 0.2 0.086 12.5 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain TPR_16 PF13432.6 CAM40729.1 - 0.056 14.1 1.9 11 6.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat MIF PF01187.18 CAM40731.1 - 4.2e-05 23.8 0.0 4.4e-05 23.8 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) S-methyl_trans PF02574.16 CAM40731.1 - 0.17 11.7 0.0 0.18 11.6 0.0 1.1 1 0 0 1 1 1 0 Homocysteine S-methyltransferase OTT_1508_deam PF14441.6 CAM40732.1 - 0.00024 21.0 0.8 0.00041 20.3 0.1 1.8 2 0 0 2 2 2 1 OTT_1508-like deaminase dCMP_cyt_deam_1 PF00383.23 CAM40732.1 - 0.063 13.2 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region ADH_zinc_N PF00107.26 CAM40733.1 - 0.00098 19.1 0.0 0.0014 18.6 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase LisH PF08513.11 CAM40734.1 - 0.048 13.6 0.1 0.16 12.0 0.1 2.0 2 0 0 2 2 2 0 LisH CDC45 PF02724.14 CAM40734.1 - 9.5 4.4 11.5 16 3.7 11.5 1.3 1 0 0 1 1 1 0 CDC45-like protein DOT1 PF08123.13 CAM40735.1 - 4.2e-15 55.8 0.2 5.9e-15 55.3 0.2 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 CAM40735.1 - 0.00016 21.5 0.0 0.00023 21.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CAM40735.1 - 0.0033 16.9 0.2 0.049 13.1 0.1 2.2 1 1 1 2 2 2 1 Putative methyltransferase Methyltransf_12 PF08242.12 CAM40735.1 - 0.0086 16.8 0.0 0.02 15.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAM40735.1 - 0.019 14.8 0.0 0.032 14.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 CAM40735.1 - 0.024 15.4 0.0 0.041 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_10 PF00331.20 CAM40735.1 - 0.062 12.5 0.0 0.079 12.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 Methyltransf_11 PF08241.12 CAM40735.1 - 0.13 12.9 0.0 0.21 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DER1 PF04511.15 CAM40736.1 - 1.1e-30 107.0 10.7 1.3e-30 106.8 10.7 1.0 1 0 0 1 1 1 1 Der1-like family Oleosin PF01277.17 CAM40736.1 - 0.0021 17.8 0.1 0.0021 17.8 0.1 2.0 3 0 0 3 3 3 1 Oleosin Pkinase PF00069.25 CAM40739.1 - 5.5e-49 166.9 0.0 7.2e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM40739.1 - 2.3e-23 82.8 0.0 3.4e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CAM40739.1 - 0.011 15.7 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 CAM40739.1 - 0.058 12.4 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase ABC1 PF03109.16 CAM40739.1 - 0.074 13.2 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 ABC1 family RIO1 PF01163.22 CAM40739.1 - 0.15 11.6 0.1 1.2 8.7 0.0 1.9 1 1 1 2 2 2 0 RIO1 family Peptidase_M20 PF01546.28 CAM40740.1 - 3.9e-18 65.9 0.0 5.6e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CAM40740.1 - 9.3e-08 32.0 0.0 1.6e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Ras PF00071.22 CAM40741.1 - 2.8e-49 166.8 0.0 3.3e-49 166.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAM40741.1 - 5.9e-33 113.6 0.0 9.8e-33 112.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAM40741.1 - 8.8e-16 57.8 0.0 1.1e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CAM40741.1 - 6.2e-06 25.7 0.0 9.2e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CAM40741.1 - 3.8e-05 23.6 0.5 0.023 14.6 0.5 3.1 2 1 1 3 3 3 1 RsgA GTPase MMR_HSR1 PF01926.23 CAM40741.1 - 4.3e-05 23.6 0.0 8.7e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 CAM40741.1 - 0.00074 19.3 0.1 0.011 15.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CAM40741.1 - 0.0042 17.5 0.1 0.0066 16.8 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain MCM PF00493.23 CAM40741.1 - 0.012 14.8 0.0 0.034 13.2 0.0 1.7 2 0 0 2 2 2 0 MCM P-loop domain GTP_EFTU PF00009.27 CAM40741.1 - 0.014 14.9 0.1 0.095 12.2 0.1 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain DAP3 PF10236.9 CAM40741.1 - 0.015 14.5 0.1 0.026 13.7 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 CAM40741.1 - 0.017 14.8 1.5 0.049 13.4 1.2 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 CAM40741.1 - 0.041 13.7 0.2 0.17 11.7 0.0 1.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 CAM40741.1 - 0.052 14.1 0.2 0.12 12.9 0.0 1.7 2 0 0 2 2 2 0 ABC transporter AAA_25 PF13481.6 CAM40741.1 - 0.062 12.9 0.4 0.42 10.1 0.4 2.1 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CAM40741.1 - 0.065 12.7 0.1 0.18 11.3 0.1 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region SRPRB PF09439.10 CAM40741.1 - 0.098 12.1 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 CAM40741.1 - 0.11 11.8 0.0 0.79 9.1 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein DUF815 PF05673.13 CAM40741.1 - 0.13 11.4 0.3 0.31 10.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) YTH PF04146.15 CAM40741.1 - 0.14 12.1 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 YT521-B-like domain G-alpha PF00503.20 CAM40741.1 - 0.14 11.2 0.5 2.5 7.2 0.2 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_23 PF13476.6 CAM40741.1 - 0.14 12.6 0.0 0.19 12.2 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CAM40741.1 - 0.15 12.1 0.1 0.51 10.3 0.1 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF2520 PF10728.9 CAM40742.1 - 0.11 12.3 1.0 0.21 11.4 0.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF2520) ABC_membrane_2 PF06472.15 CAM40743.1 - 3e-66 223.6 0.3 4e-66 223.2 0.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 CAM40743.1 - 4.2e-18 66.2 0.0 7.8e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CAM40743.1 - 0.0038 17.1 0.0 0.0071 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CAM40743.1 - 0.004 16.6 0.0 0.24 10.8 0.0 2.6 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain ABC_membrane PF00664.23 CAM40743.1 - 0.0084 15.8 0.4 0.0084 15.8 0.4 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region NACHT PF05729.12 CAM40743.1 - 0.016 15.1 0.1 0.25 11.3 0.0 2.7 3 0 0 3 3 3 0 NACHT domain AAA_29 PF13555.6 CAM40743.1 - 0.018 14.7 0.1 0.049 13.4 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 CAM40743.1 - 0.021 14.6 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.8 CAM40743.1 - 0.021 12.4 0.5 0.037 11.6 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_23 PF13476.6 CAM40743.1 - 0.029 14.9 0.0 0.059 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CAM40743.1 - 0.069 12.5 0.2 0.21 10.9 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 CAM40743.1 - 0.1 12.9 0.7 2.5 8.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain PgaD PF13994.6 CAM40743.1 - 0.1 12.6 0.0 0.31 11.1 0.0 1.8 1 0 0 1 1 1 0 PgaD-like protein DUF87 PF01935.17 CAM40743.1 - 0.1 12.6 0.2 0.21 11.7 0.2 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 CAM40743.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family NOG1_N PF17835.1 CAM40744.2 - 8e-53 178.7 0.3 1.5e-52 177.8 0.3 1.5 1 0 0 1 1 1 1 NOG1 N-terminal helical domain NOG1 PF06858.14 CAM40744.2 - 6.7e-28 96.2 0.0 2e-27 94.8 0.0 1.8 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 CAM40744.2 - 1.9e-21 75.7 6.2 5.2e-21 74.4 6.2 1.8 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 CAM40744.2 - 2.7e-17 62.9 0.0 5.5e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CAM40744.2 - 7.8e-10 38.5 0.0 1.5e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CAM40744.2 - 0.0004 20.3 0.0 1.5 8.7 0.0 2.7 2 1 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 CAM40744.2 - 0.0075 15.6 0.1 0.022 14.1 0.0 1.8 2 0 0 2 2 2 1 AIG1 family Ras PF00071.22 CAM40744.2 - 0.015 14.9 0.1 0.042 13.4 0.1 1.7 1 1 0 1 1 1 0 Ras family Dynamin_N PF00350.23 CAM40744.2 - 0.083 12.9 0.1 5.7 7.0 0.0 2.6 1 1 1 2 2 2 0 Dynamin family IQ PF00612.27 CAM40745.1 - 0.0013 18.4 0.5 0.0045 16.7 0.5 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif FOP_dimer PF09398.10 CAM40747.1 - 6.4e-12 45.6 0.0 1.3e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 FOP N terminal dimerisation domain LisH_2 PF16045.5 CAM40747.1 - 1.6e-05 23.8 0.0 2.6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 LisH LisH PF08513.11 CAM40747.1 - 0.012 15.5 0.1 0.024 14.6 0.1 1.5 1 0 0 1 1 1 0 LisH Snf7 PF03357.21 CAM40748.1 - 9.1e-12 44.9 9.6 9.1e-12 44.9 9.6 2.0 1 1 1 2 2 2 2 Snf7 LAP2alpha PF11560.8 CAM40748.1 - 0.041 13.3 0.8 0.06 12.8 0.5 1.4 1 1 0 1 1 1 0 Lamina-associated polypeptide 2 alpha Ist1 PF03398.14 CAM40748.1 - 0.051 13.5 4.3 0.13 12.2 4.3 1.7 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway DUF1463 PF07316.11 CAM40748.1 - 0.25 11.2 1.6 14 5.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1463) CAF1C_H4-bd PF12265.8 CAM40749.1 - 5.8e-12 45.7 0.0 1.3e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex DUF2457 PF10446.9 CAM40749.1 - 0.002 17.4 21.3 0.002 17.4 21.3 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF2457) WD40 PF00400.32 CAM40749.1 - 0.25 12.3 0.0 0.25 12.3 0.0 4.3 5 0 0 5 5 5 0 WD domain, G-beta repeat SDA1 PF05285.12 CAM40749.1 - 1.5 8.2 25.0 2.5 7.4 16.6 2.2 2 0 0 2 2 2 0 SDA1 Utp14 PF04615.13 CAM40749.1 - 3.9 5.9 18.2 3 6.3 11.9 2.0 2 0 0 2 2 2 0 Utp14 protein Pho88 PF10032.9 CAM40750.1 - 2.1e-26 92.3 0.0 2.5e-26 92.1 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Pribosyltran_N PF13793.6 CAM40751.1 - 2.5e-40 137.0 0.2 1.2e-39 134.9 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CAM40751.1 - 4.9e-23 82.1 0.7 3.3e-22 79.4 0.3 2.1 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CAM40751.1 - 8.5e-18 64.4 0.2 1.9e-17 63.3 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CAM40751.1 - 0.028 13.9 0.2 0.048 13.1 0.2 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase HTH_CodY PF08222.11 CAM40751.1 - 0.051 13.1 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 CodY helix-turn-helix domain zn-ribbon_14 PF16503.5 CAM40751.1 - 0.12 11.9 0.4 0.31 10.6 0.4 1.7 1 0 0 1 1 1 0 Zinc-ribbon CxC3 PF18804.1 CAM40751.1 - 0.17 11.8 0.5 0.37 10.6 0.2 1.7 2 0 0 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases MHYT PF03707.16 CAM40752.1 - 1.6 9.0 9.0 0.77 10.0 1.3 3.0 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat PRORP PF16953.5 CAM40753.2 - 1.3e-17 64.2 0.1 7.8e-07 28.9 0.1 4.5 5 0 0 5 5 5 4 Protein-only RNase P PPR_long PF17177.4 CAM40753.2 - 1.2e-10 41.2 0.1 2.1e-10 40.4 0.1 1.3 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP Pkinase PF00069.25 CAM40756.1 - 2.7e-60 204.0 0.0 3.5e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM40756.1 - 9.4e-38 130.0 0.1 1.2e-37 129.6 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM40756.1 - 1.5e-07 31.1 0.0 2.1e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PH PF00169.29 CAM40756.1 - 3.8e-07 30.6 0.0 1.2e-06 28.9 0.0 1.9 2 0 0 2 2 2 1 PH domain Pkinase_fungal PF17667.1 CAM40756.1 - 0.019 13.8 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF1636 PF07845.11 CAM40756.1 - 0.043 14.3 0.0 0.086 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1636) PH_11 PF15413.6 CAM40756.1 - 0.05 14.0 0.1 0.14 12.6 0.1 1.8 1 1 0 1 1 1 0 Pleckstrin homology domain PH_9 PF15410.6 CAM40756.1 - 0.12 12.7 0.0 6.1 7.2 0.0 2.6 1 1 0 1 1 1 0 Pleckstrin homology domain EBP50_C PF09007.11 CAM40757.1 - 7.8 7.5 9.9 3.2 8.7 0.0 3.2 3 0 0 3 3 3 0 EBP50, C-terminal PEN-2 PF10251.9 CAM40758.1 - 9.5e-08 32.4 6.9 1.3e-07 31.9 6.9 1.4 1 1 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase Ferric_reduct PF01794.19 CAM40758.1 - 0.016 15.3 0.9 0.02 15.0 0.9 1.3 1 0 0 1 1 1 0 Ferric reductase like transmembrane component DUF4271 PF14093.6 CAM40758.1 - 0.069 13.1 1.5 0.086 12.7 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) Peptidase_C2 PF00648.21 CAM40759.2 - 4e-34 118.0 0.0 6.5e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 CAM40759.2 - 1.8e-09 38.0 0.0 0.0003 21.1 0.0 3.6 3 0 0 3 3 3 2 Calpain large subunit, domain III MIT PF04212.18 CAM40759.2 - 3.9e-07 30.1 0.7 1e-06 28.7 0.5 1.8 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 CAM40759.2 - 0.16 12.2 0.2 2.8 8.3 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Acyl-CoA_dh_1 PF00441.24 CAM40761.1 - 0.23 11.7 4.2 0.12 12.5 1.6 1.9 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Nup84_Nup100 PF04121.13 CAM40762.1 - 2.9e-08 32.3 0.6 0.00082 17.6 0.0 2.9 2 1 1 3 3 3 2 Nuclear pore protein 84 / 107 Peptidase_M23 PF01551.22 CAM40762.1 - 0.042 14.1 0.0 0.48 10.7 0.0 2.4 2 0 0 2 2 2 0 Peptidase family M23 DUF383 PF04063.14 CAM40763.1 - 0.026 14.2 0.1 0.081 12.6 0.0 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF383) HEAT PF02985.22 CAM40763.1 - 0.063 13.6 0.0 3.6 8.1 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat RNA_pol_A_CTD PF03118.15 CAM40763.1 - 0.076 12.8 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain KAP PF05804.12 CAM40763.1 - 0.098 10.8 0.1 0.14 10.3 0.1 1.2 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) Pkinase PF00069.25 CAM40765.1 - 3.1e-46 157.9 0.0 5.6e-35 121.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM40765.1 - 3.5e-26 92.0 0.2 1.2e-15 57.5 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase E1-E2_ATPase PF00122.20 CAM40767.2 - 2.1e-45 154.5 0.4 2.1e-45 154.5 0.4 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CAM40767.2 - 1.4e-34 120.2 0.2 2.9e-34 119.2 0.2 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 CAM40767.2 - 9.8e-34 115.6 1.7 4.7e-10 39.8 0.2 3.6 3 0 0 3 3 3 3 Heavy-metal-associated domain Hydrolase_3 PF08282.12 CAM40767.2 - 1.1e-06 28.6 0.2 1.8e-05 24.6 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CoA_binding_2 PF13380.6 CAM40767.2 - 0.00025 21.5 0.3 0.00088 19.8 0.3 1.9 1 0 0 1 1 1 1 CoA binding domain cpYpsA PF12694.7 CAM40767.2 - 0.014 15.2 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 Circularly permutated YpsA SLOG family HAD PF12710.7 CAM40767.2 - 0.016 15.7 0.1 0.054 13.9 0.1 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase TctB PF07331.11 CAM40767.2 - 0.022 15.0 0.7 0.022 15.0 0.7 3.3 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family ProQ_C PF17516.2 CAM40767.2 - 0.16 11.5 1.5 0.97 8.9 0.0 3.0 3 0 0 3 3 3 0 ProQ C-terminal domain His_Phos_1 PF00300.22 CAM40768.2 - 8.5e-29 100.6 0.1 7.3e-21 74.8 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) His_Phos_1 PF00300.22 CAM40769.1 - 5.7e-17 62.0 0.1 2.5e-09 37.1 0.0 2.5 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) zf-HIT PF04438.16 CAM40770.1 - 5.4e-07 29.4 14.6 1.4e-06 28.1 14.6 1.7 1 0 0 1 1 1 1 HIT zinc finger zf-B_box PF00643.24 CAM40770.1 - 0.07 13.3 6.0 0.21 11.7 6.0 1.8 1 0 0 1 1 1 0 B-box zinc finger zf-MYND PF01753.18 CAM40770.1 - 0.083 13.0 12.2 0.18 11.9 12.2 1.6 1 0 0 1 1 1 0 MYND finger Kinesin PF00225.23 CAM40772.1 - 1.6e-80 270.6 0.0 4.3e-80 269.1 0.0 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CAM40772.1 - 1.4e-22 80.3 0.0 2.9e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding SUIM_assoc PF16619.5 CAM40772.1 - 0.85 9.7 9.4 0.091 12.8 0.5 3.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Dynein_heavy PF03028.15 CAM40773.1 - 5.8e-05 23.2 0.0 0.00013 22.1 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain WD40 PF00400.32 CAM40773.1 - 0.087 13.7 16.6 11 7.1 0.0 6.9 8 0 0 8 8 8 0 WD domain, G-beta repeat Acid_PPase PF12689.7 CAM40774.1 - 6.9e-51 172.4 0.0 8e-51 172.2 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase Hydrolase PF00702.26 CAM40774.1 - 0.042 14.1 0.1 0.045 14.0 0.1 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase TAF1_subA PF14929.6 CAM40774.1 - 0.075 12.4 0.0 0.086 12.2 0.0 1.1 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A NIF PF03031.18 CAM40774.1 - 0.11 12.3 0.0 0.37 10.6 0.0 1.8 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase HAD PF12710.7 CAM40774.1 - 0.12 12.8 0.0 0.27 11.6 0.0 1.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Herpes_U30 PF04523.13 CAM40775.1 - 0.028 12.3 6.1 0.53 8.1 0.8 2.3 2 0 0 2 2 2 0 Herpes virus tegument protein U30 P53_C PF11619.8 CAM40775.1 - 0.085 12.9 0.0 0.27 11.3 0.0 1.8 1 0 0 1 1 1 0 Transcription factor P53 - C terminal domain DUF724 PF05266.14 CAM40775.1 - 0.14 12.0 0.4 0.39 10.5 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Tup_N PF08581.10 CAM40775.1 - 0.95 9.8 5.9 0.57 10.5 0.7 2.6 2 0 0 2 2 2 0 Tup N-terminal CLZ PF16526.5 CAM40775.1 - 6.2 7.3 8.5 15 6.0 1.1 3.0 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF29 PF01724.16 CAM40778.2 - 0.05 13.8 0.0 0.082 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF29 DUF2798 PF11391.8 CAM40779.1 - 1.6 8.8 5.8 13 5.9 3.8 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2798) DUF1279 PF06916.13 CAM40780.1 - 0.016 15.8 0.1 0.038 14.5 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1279) RTP801_C PF07809.11 CAM40780.1 - 0.016 15.1 0.0 1.7 8.6 0.0 2.2 2 0 0 2 2 2 0 RTP801 C-terminal region CFAP91 PF14738.6 CAM40781.2 - 2e-45 154.6 3.2 2e-45 154.6 3.2 2.8 3 1 0 3 3 3 1 Cilia- and flagella-associated protein 91 DUF3761 PF12587.8 CAM40783.1 - 0.047 14.1 0.0 0.12 12.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3761) Baculo_IE-1 PF05290.11 CAM40784.1 - 0.001 19.0 2.4 0.0016 18.4 2.4 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4_3 PF13920.6 CAM40784.1 - 0.11 12.3 14.1 0.21 11.5 14.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Herpes_UL32 PF06070.11 CAM40784.1 - 0.13 10.0 8.9 0.24 9.1 6.8 2.0 2 0 0 2 2 2 0 Herpesvirus large structural phosphoprotein UL32 Bac_small_YrzI PF09501.10 CAM40784.1 - 0.62 10.2 1.9 1.8 8.8 1.9 1.7 1 1 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) Glyco_hydro_85 PF03644.13 CAM40785.1 - 2.2e-84 283.5 0.0 3.4e-84 282.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Peptidase_C97 PF05903.14 CAM40785.1 - 1.2e-25 90.1 0.0 2e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUB PF09409.10 CAM40785.1 - 2.1e-14 53.2 0.0 1.2e-13 50.8 0.0 2.0 1 1 1 2 2 2 1 PUB domain DUF3421 PF11901.8 CAM40785.1 - 1.5e-07 31.4 0.2 0.0019 18.2 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF3421) HAUS-augmin3 PF14932.6 CAM40786.1 - 2.1e-07 30.8 117.3 0.15 11.6 8.8 10.0 2 1 12 14 14 14 12 HAUS augmin-like complex subunit 3 BRE1 PF08647.11 CAM40786.1 - 6.2e-05 23.0 93.4 0.73 9.9 2.7 12.1 3 1 14 17 17 17 15 BRE1 E3 ubiquitin ligase DUF1964 PF09244.10 CAM40786.1 - 0.032 14.7 35.2 95 3.5 0.1 12.0 3 3 10 14 14 14 0 Domain of unknown function (DUF1964) SlyX PF04102.12 CAM40786.1 - 0.087 13.4 95.3 6.9 7.4 2.6 15.7 3 2 16 19 19 19 0 SlyX GIT_CC PF16559.5 CAM40786.1 - 0.16 11.9 51.9 1.1e+02 2.8 0.1 16.7 17 3 3 20 20 20 0 GIT coiled-coil Rho guanine nucleotide exchange factor Tup_N PF08581.10 CAM40786.1 - 3 8.2 8.1 2 8.8 2.3 4.0 2 0 0 2 2 2 0 Tup N-terminal zf-MYND PF01753.18 CAM40787.1 - 3.5e-08 33.4 11.7 6.8e-08 32.5 11.7 1.5 1 0 0 1 1 1 1 MYND finger Pkinase PF00069.25 CAM40788.2 - 2.5e-54 184.4 0.0 1e-48 166.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM40788.2 - 1.7e-39 135.7 0.0 1.7e-37 129.1 0.0 2.6 3 0 0 3 3 3 1 Protein tyrosine kinase Kdo PF06293.14 CAM40788.2 - 6.3e-05 22.4 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CAM40788.2 - 0.0001 21.7 0.0 0.00035 20.0 0.0 1.6 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 CAM40788.2 - 0.008 15.8 0.0 0.02 14.5 0.0 1.6 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 CAM40788.2 - 0.011 15.7 0.5 1.2 9.1 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CAM40788.2 - 0.03 13.1 0.0 0.11 11.3 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Epimerase PF01370.21 CAM40789.1 - 3.1e-39 134.9 0.0 3.9e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CAM40789.1 - 1.5e-32 113.4 0.0 1.1e-30 107.3 0.0 2.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 CAM40789.1 - 1e-14 54.4 0.0 8.3e-14 51.4 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 CAM40789.1 - 6.7e-12 45.0 0.0 7.5e-10 38.3 0.0 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CAM40789.1 - 2.5e-08 33.4 0.0 4.1e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein KR PF08659.10 CAM40789.1 - 9.7e-06 25.6 0.0 3.1e-05 24.0 0.0 1.8 2 1 0 2 2 2 1 KR domain RmlD_sub_bind PF04321.17 CAM40789.1 - 9.2e-05 21.7 0.0 0.00048 19.3 0.0 2.1 2 1 0 2 2 2 1 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 CAM40789.1 - 0.03 14.6 0.1 0.13 12.5 0.1 2.1 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 CAM40789.1 - 0.065 13.1 0.0 1.8 8.4 0.0 2.2 1 1 0 1 1 1 0 NAD(P)H-binding TrkA_N PF02254.18 CAM40789.1 - 0.077 13.3 0.1 3 8.2 0.0 2.8 3 0 0 3 3 3 0 TrkA-N domain DUF4232 PF14016.6 CAM40789.1 - 0.079 13.1 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) YAcAr PF10686.9 CAM40789.1 - 0.12 12.4 0.0 0.59 10.1 0.0 2.1 2 0 0 2 2 2 0 YspA, cpYpsA-related SLOG family CDC45 PF02724.14 CAM40791.1 - 7.5e-82 275.6 0.0 9.5e-82 275.3 0.0 1.1 1 0 0 1 1 1 1 CDC45-like protein FapA PF03961.13 CAM40792.2 - 1.1 7.8 3.7 1.5 7.4 1.9 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A GIT_CC PF16559.5 CAM40792.2 - 5.2 7.0 7.0 21 5.0 0.1 3.5 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor CoA_trans PF01144.23 CAM40793.2 - 3.1e-97 324.2 1.7 8e-60 201.9 0.4 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 CAM40793.2 - 0.015 15.2 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain RabGAP-TBC PF00566.18 CAM40794.1 - 1.3e-07 31.5 0.1 2.2e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain FAM104 PF15434.6 CAM40794.1 - 0.36 11.4 1.1 0.78 10.3 0.1 2.0 2 0 0 2 2 2 0 Family 104 Tom22 PF04281.13 CAM40795.1 - 0.027 14.3 0.4 0.048 13.5 0.4 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 GRASP55_65 PF04495.14 CAM40796.1 - 9.2e-42 142.6 0.0 1.1e-36 126.2 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain HSP90 PF00183.18 CAM40797.1 - 7.1e-95 318.9 3.4 3e-93 313.5 0.6 2.0 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 CAM40797.1 - 5.3e-11 42.5 0.0 1.4e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CAM40797.1 - 3e-07 30.9 0.0 5.6e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DPRP PF04244.13 CAM40797.1 - 0.0049 16.8 0.2 0.0087 15.9 0.2 1.3 1 0 0 1 1 1 1 Deoxyribodipyrimidine photo-lyase-related protein OSCP PF00213.18 CAM40797.1 - 0.1 12.7 0.2 0.23 11.6 0.2 1.5 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit MMR_HSR1 PF01926.23 CAM40798.1 - 1.5e-17 63.7 0.0 3.3e-13 49.7 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CAM40798.1 - 1.7e-10 40.7 2.0 6.9e-09 35.4 0.2 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CAM40798.1 - 1.1e-05 25.5 0.7 0.00017 21.5 0.7 2.4 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 CAM40798.1 - 2.2e-05 24.1 0.0 0.00096 18.7 0.2 3.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CAM40798.1 - 0.0038 17.3 0.8 0.046 13.8 0.2 2.5 2 1 1 3 3 3 1 Dynamin family AAA_18 PF13238.6 CAM40798.1 - 0.017 15.6 0.0 0.064 13.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 CAM40798.1 - 0.053 12.5 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Diphthamide_syn PF01866.17 CAM40799.1 - 1.4e-43 149.5 0.5 1.8e-23 83.4 0.0 3.0 2 1 0 2 2 2 2 Putative diphthamide synthesis protein TMEM119 PF15724.5 CAM40799.1 - 0.028 14.5 0.4 0.028 14.5 0.4 1.9 2 0 0 2 2 2 0 TMEM119 family PEN-2 PF10251.9 CAM40799.1 - 0.23 11.9 0.2 0.86 10.1 0.0 1.9 2 0 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase RE_NgoFVII PF09565.10 CAM40802.2 - 0.0022 17.4 4.1 0.0044 16.4 4.1 1.4 1 0 0 1 1 1 1 NgoFVII restriction endonuclease zf-C3HC PF07967.13 CAM40803.1 - 0.037 14.1 0.1 11 6.1 0.0 2.5 2 0 0 2 2 2 0 C3HC zinc finger-like RILP PF11461.8 CAM40804.2 - 0.035 14.3 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 Rab interacting lysosomal protein Tox-WTIP PF15654.6 CAM40806.1 - 0.045 14.2 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 Toxin with a conserved tryptophan and TIP tripeptide motif HNH_3 PF13392.6 CAM40807.1 - 0.049 13.4 0.0 0.2 11.4 0.0 2.0 2 0 0 2 2 2 0 HNH endonuclease KorB PF08535.10 CAM40807.1 - 0.071 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 KorB domain Rad51 PF08423.11 CAM40808.1 - 1.3e-34 119.7 0.0 1.5e-21 76.9 0.1 3.7 3 1 1 4 4 4 3 Rad51 AAA_25 PF13481.6 CAM40808.1 - 1e-08 35.0 0.1 4.2e-08 33.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 CAM40808.1 - 2.3e-05 23.9 0.3 8.1e-05 22.1 0.2 1.9 2 0 0 2 2 2 1 KaiC RecA PF00154.21 CAM40808.1 - 0.005 16.3 0.1 0.01 15.3 0.1 1.4 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA PF00004.29 CAM40808.1 - 0.12 12.8 0.1 0.43 11.0 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SPX PF03105.19 CAM40808.1 - 0.26 11.2 1.0 0.43 10.4 1.0 1.3 1 0 0 1 1 1 0 SPX domain Radial_spoke PF04712.12 CAM40809.2 - 4.3e-07 29.3 0.0 6.5e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Radial spokehead-like protein NUC173 PF08161.12 CAM40812.2 - 6.9e-16 58.5 4.9 2.4e-15 56.7 0.6 3.4 2 1 1 3 3 3 1 NUC173 domain Peptidase_M32 PF02074.15 CAM40813.1 - 7.7e-155 516.4 0.0 8.7e-155 516.2 0.0 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase Iso_dh PF00180.20 CAM40814.1 - 1.7e-106 356.3 0.0 2.2e-106 356.0 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PdxA PF04166.12 CAM40814.1 - 0.0037 16.7 0.1 0.0067 15.9 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthetic protein PdxA Kinesin PF00225.23 CAM40815.2 - 3.6e-102 341.7 0.5 6.6e-102 340.8 0.5 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CAM40815.2 - 7e-21 74.7 0.0 2.5e-20 72.9 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding AAA_16 PF13191.6 CAM40815.2 - 4.2e-05 24.0 0.8 0.0076 16.6 0.0 4.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 CAM40815.2 - 0.00016 22.0 3.9 0.035 14.4 0.1 3.9 3 1 1 4 4 4 1 AAA domain Mito_fiss_reg PF05308.11 CAM40815.2 - 0.0012 19.0 0.5 0.0039 17.3 0.5 1.9 1 0 0 1 1 1 1 Mitochondrial fission regulator Ras PF00071.22 CAM40815.2 - 0.004 16.8 0.0 0.53 9.9 0.0 3.0 3 0 0 3 3 2 1 Ras family Mg_chelatase PF01078.21 CAM40815.2 - 0.015 14.7 0.0 0.38 10.1 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 CAM40815.2 - 0.016 15.2 1.1 0.039 13.9 0.8 1.8 2 0 0 2 2 1 0 RsgA GTPase Roc PF08477.13 CAM40815.2 - 0.024 14.9 0.0 0.89 9.8 0.0 3.3 4 0 0 4 4 3 0 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 CAM40815.2 - 0.026 14.2 0.0 3.9 7.2 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_28 PF13521.6 CAM40815.2 - 0.034 14.4 0.0 0.12 12.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 CAM40815.2 - 0.036 13.4 4.1 2.3 7.5 0.2 3.4 4 0 0 4 4 4 0 FtsK/SpoIIIE family AAA_29 PF13555.6 CAM40815.2 - 0.043 13.5 0.0 0.3 10.9 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 CAM40815.2 - 0.046 14.2 0.1 0.25 11.9 0.0 2.2 2 0 0 2 2 2 0 ABC transporter RNA_helicase PF00910.22 CAM40815.2 - 0.057 13.8 0.6 4.6 7.7 0.0 3.6 3 0 0 3 3 3 0 RNA helicase MMR_HSR1 PF01926.23 CAM40815.2 - 0.071 13.2 1.0 5.1 7.2 0.3 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.12 CAM40815.2 - 0.08 12.9 0.3 0.93 9.4 0.0 2.6 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 CAM40815.2 - 0.11 12.3 0.2 2.8 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CAM40815.2 - 0.11 12.0 0.3 3.7 7.0 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region G-alpha PF00503.20 CAM40815.2 - 0.23 10.6 0.0 0.47 9.5 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit Kinesin_assoc PF16183.5 CAM40815.2 - 1.9 8.6 6.7 0.4 10.8 1.6 2.6 2 1 0 2 2 2 0 Kinesin-associated Peptidase_M17 PF00883.21 CAM40816.1 - 7e-90 301.5 0.1 9.8e-90 301.0 0.1 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Pdase_M17_N2 PF18295.1 CAM40816.1 - 1.5e-30 105.9 1.8 3e-30 105.0 1.8 1.5 1 0 0 1 1 1 1 M17 aminopeptidase N-terminal domain 2 SAD_SRA PF02182.17 CAM40816.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 SAD/SRA domain 3HCDH_N PF02737.18 CAM40820.2 - 2.2e-41 141.7 0.0 4.2e-41 140.8 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 CAM40820.2 - 3.1e-30 105.3 0.0 5e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 CAM40820.2 - 5.8e-19 68.5 0.0 6.8e-09 36.2 0.0 3.6 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 CAM40820.2 - 5.3e-13 49.2 0.0 8.7e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DAO PF01266.24 CAM40820.2 - 0.018 14.6 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CAM40820.2 - 0.019 15.0 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Shikimate_DH PF01488.20 CAM40820.2 - 0.05 13.7 0.1 0.13 12.3 0.1 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 CAM40820.2 - 0.063 13.5 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Peptidase_M16_C PF05193.21 CAM40821.1 - 3e-19 69.8 0.0 5.5e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CAM40821.1 - 0.0011 19.0 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) SRPRB PF09439.10 CAM40822.2 - 6.5e-21 74.6 0.0 1.3e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CAM40822.2 - 0.00015 21.3 0.1 0.00032 20.3 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CAM40822.2 - 0.00033 20.7 0.0 0.00072 19.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF463 PF04317.12 CAM40822.2 - 0.058 12.3 0.1 1.1 8.1 0.0 2.3 2 0 0 2 2 2 0 YcjX-like family, DUF463 WD40 PF00400.32 CAM40823.1 - 0.00073 20.3 2.0 24 6.0 0.0 5.6 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM40823.1 - 0.00089 19.5 0.7 4.4 7.7 0.0 4.7 2 2 4 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain HemY_N PF07219.13 CAM40823.1 - 0.063 13.5 2.0 0.35 11.1 0.0 2.9 3 0 0 3 3 3 0 HemY protein N-terminus Pep3_Vps18 PF05131.14 CAM40823.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Pep3/Vps18/deep orange family LIM PF00412.22 CAM40824.1 - 1.3e-05 25.4 1.1 2.2e-05 24.6 1.1 1.4 1 0 0 1 1 1 1 LIM domain DUF4193 PF13834.6 CAM40824.1 - 3.4 8.2 9.3 2.4 8.7 3.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4193) ThiF PF00899.21 CAM40825.2 - 8.3e-07 28.6 0.0 4.3e-05 23.0 0.0 2.3 2 1 0 2 2 2 2 ThiF family zf-CCHC PF00098.23 CAM40826.1 - 2.2 8.5 5.7 7.1 6.9 0.8 2.9 2 0 0 2 2 2 0 Zinc knuckle PKcGMP_CC PF16808.5 CAM40827.1 - 4 7.4 13.6 0.93 9.4 0.1 4.3 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DnaJ PF00226.31 CAM40829.1 - 3.4e-09 36.7 0.3 1.2e-08 34.9 0.0 2.0 2 0 0 2 2 2 1 DnaJ domain PSP1 PF04468.12 CAM40829.1 - 0.22 11.8 0.9 2.3 8.6 0.2 2.4 2 1 0 2 2 2 0 PSP1 C-terminal conserved region Dor1 PF04124.12 CAM40829.1 - 0.23 10.1 4.2 0.12 11.1 0.6 2.0 2 0 0 2 2 2 0 Dor1-like family Takusan PF04822.13 CAM40829.1 - 0.44 10.4 5.8 1.5 8.7 2.1 2.5 2 1 0 2 2 2 0 Takusan Holin_BhlA PF10960.8 CAM40829.1 - 0.54 10.3 2.5 0.46 10.5 0.1 2.0 2 0 0 2 2 2 0 BhlA holin family LUC7 PF03194.15 CAM40829.1 - 4.1 7.0 7.8 3.1 7.4 5.1 1.9 2 0 0 2 2 2 0 LUC7 N_terminus MCM PF00493.23 CAM40830.2 - 3.2e-83 278.2 0.0 5.6e-83 277.5 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CAM40830.2 - 3.1e-26 91.7 0.0 5.5e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CAM40830.2 - 1.9e-21 76.3 0.0 3.9e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CAM40830.2 - 3.6e-10 40.4 0.0 1.4e-09 38.5 0.0 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 CAM40830.2 - 1.5e-08 34.2 0.2 6.5e-07 28.9 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CAM40830.2 - 0.00049 19.9 0.0 0.002 17.9 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 CAM40830.2 - 0.0019 18.1 0.0 0.0042 17.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CAM40830.2 - 0.08 12.9 0.0 0.35 10.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 CAM40830.2 - 0.11 13.0 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Complex1_LYR PF05347.15 CAM40831.1 - 2.7e-05 24.1 1.6 4.4e-05 23.4 1.6 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) ketoacyl-synt PF00109.26 CAM40832.1 - 2.2e-39 135.6 2.6 1.1e-37 130.0 2.6 2.3 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 CAM40832.1 - 2e-27 95.6 0.4 4.3e-27 94.5 0.4 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain CoA_binding_2 PF13380.6 CAM40833.1 - 0.021 15.3 0.1 0.96 10.0 0.1 2.3 2 0 0 2 2 2 0 CoA binding domain GTP_EFTU PF00009.27 CAM40834.1 - 2.2e-34 118.7 0.0 7.5e-34 117.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CAM40834.1 - 1.2e-15 57.5 0.0 2.8e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 CAM40834.1 - 3.3e-10 40.2 1.1 2.2e-07 31.2 0.0 3.0 2 0 0 2 2 2 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 CAM40834.1 - 1.2e-08 34.7 1.5 1.9e-08 34.1 0.7 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 CAM40834.1 - 4.9e-08 33.1 0.0 4.3e-07 30.0 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 CAM40834.1 - 6.1e-05 23.2 0.0 0.00014 22.1 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 CAM40834.1 - 0.0048 16.7 0.0 0.017 14.9 0.0 1.9 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 CAM40834.1 - 0.016 15.6 0.0 0.016 15.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Ras PF00071.22 CAM40834.1 - 0.019 14.6 0.0 0.088 12.4 0.0 2.1 1 1 0 1 1 1 0 Ras family Cwf_Cwc_15 PF04889.12 CAM40834.1 - 1.2 8.9 33.5 2.3 7.9 33.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CAF-1_p150 PF11600.8 CAM40834.1 - 2.1 8.0 50.7 4.3 7.0 14.8 2.4 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Dynamin_N PF00350.23 CAM40834.1 - 7.2 6.6 21.2 0.043 13.9 4.9 4.0 1 1 0 2 2 1 0 Dynamin family DUF4520 PF15016.6 CAM40835.2 - 6e-22 77.5 0.1 1.3e-18 66.9 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4520) POLO_box PF00659.18 CAM40835.2 - 0.005 17.0 0.0 0.093 12.9 0.0 2.5 2 0 0 2 2 2 1 POLO box duplicated region Corona_NS3b PF03053.14 CAM40835.2 - 0.16 11.7 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 ORF3b coronavirus protein UQ_con PF00179.26 CAM40837.1 - 9.7e-33 112.8 0.0 1.1e-32 112.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Beach PF02138.18 CAM40838.2 - 5e-97 324.6 0.0 8e-97 323.9 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain Laminin_G_3 PF13385.6 CAM40838.2 - 3.7e-08 33.7 0.4 7.9e-08 32.6 0.4 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily GTP_EFTU PF00009.27 CAM40839.1 - 9.9e-17 61.1 0.0 6.8e-16 58.4 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CAM40839.1 - 3.3e-06 27.4 0.5 8.6e-06 26.1 0.5 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 CAM40839.1 - 1.6e-05 25.1 0.2 4.5e-05 23.7 0.2 1.8 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 CAM40839.1 - 0.04 14.0 0.0 0.23 11.5 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase Tape_meas_lam_C PF09718.10 CAM40840.1 - 0.022 14.9 0.1 0.045 13.9 0.1 1.5 1 1 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) TFIIS_C PF01096.18 CAM40841.1 - 3.3e-15 55.6 7.0 6.2e-15 54.8 7.0 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) PWWP PF00855.17 CAM40841.1 - 1.8e-06 28.3 0.1 8.2e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 PWWP domain Med26 PF08711.11 CAM40841.1 - 0.099 12.7 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 TFIIS helical bundle-like domain PWWP PF00855.17 CAM40842.1 - 6.2e-12 45.8 1.1 9.7e-12 45.1 0.0 1.9 2 0 0 2 2 2 1 PWWP domain Med26 PF08711.11 CAM40842.1 - 7.2e-08 32.3 0.0 1.6e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Zn_ribbon_SprT PF17283.2 CAM40842.1 - 0.00024 21.0 0.9 0.00071 19.4 0.9 1.8 1 0 0 1 1 1 1 SprT-like zinc ribbon domain Lar_restr_allev PF14354.6 CAM40842.1 - 0.0028 18.0 0.4 0.0074 16.6 0.4 1.7 1 0 0 1 1 1 1 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.7 CAM40842.1 - 0.038 14.0 0.9 0.038 14.0 0.9 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain CDC27 PF09507.10 CAM40842.1 - 0.16 11.3 11.2 0.25 10.7 11.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 zinc_ribbon_4 PF13717.6 CAM40842.1 - 0.28 11.1 1.2 4 7.4 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain SRP-alpha_N PF04086.13 CAM40842.1 - 3.8 7.4 12.5 5.6 6.8 12.5 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CHAP PF05257.16 CAM40843.2 - 1.3e-17 64.1 0.0 2.5e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 CHAP domain Amidase_6 PF12671.7 CAM40843.2 - 0.017 15.2 0.0 0.042 13.9 0.0 1.5 1 1 0 1 1 1 0 Putative amidase domain ABC2_membrane_3 PF12698.7 CAM40844.1 - 0.032 13.4 0.1 0.054 12.6 0.1 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein Apt1 PF10351.9 CAM40844.1 - 1.4 7.7 7.0 1.9 7.3 7.0 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 CAM40844.1 - 9.6 6.0 13.7 16 5.2 13.7 1.3 1 0 0 1 1 1 0 SPX domain CHAP PF05257.16 CAM40846.2 - 2.8e-15 56.7 0.0 5.3e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 CHAP domain CHAP PF05257.16 CAM40847.2 - 0.00022 21.7 0.1 0.001 19.6 0.1 2.2 1 1 0 1 1 1 1 CHAP domain bHLH-MYC_N PF14215.6 CAM40849.1 - 0.044 14.1 0.1 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal LapA_dom PF06305.11 CAM40850.1 - 0.12 12.2 0.2 0.27 11.1 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Kinesin PF00225.23 CAM40851.2 - 0.0099 14.8 0.0 1.2 8.0 0.0 3.1 2 2 0 2 2 2 2 Kinesin motor domain Kinesin PF00225.23 CAM40852.1 - 3.3e-05 23.0 0.0 1 8.2 0.0 4.1 4 0 0 4 4 4 3 Kinesin motor domain RRM_occluded PF16842.5 CAM40852.1 - 0.1 12.5 0.0 0.96 9.4 0.0 2.6 2 0 0 2 2 2 0 Occluded RNA-recognition motif DUF4835 PF16119.5 CAM40856.1 - 0.05 12.7 0.5 0.096 11.8 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4835) TFIIF_alpha PF05793.12 CAM40857.1 - 0.1 11.2 4.6 0.1 11.2 1.0 2.2 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DOR PF14839.6 CAM40859.1 - 1 9.3 9.3 1.6 8.6 3.5 2.1 2 0 0 2 2 2 0 DOR family DUF658 PF04936.12 CAM40860.1 - 0.86 9.3 2.7 1.6 8.5 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF658) RAP1 PF07218.11 CAM40862.1 - 0.95 7.7 7.9 1.7 6.8 7.9 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ABC_tran PF00005.27 CAM40864.1 - 4.1e-11 43.5 0.0 5.1e-05 23.8 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SbcCD_C PF13558.6 CAM40864.1 - 0.001 19.3 0.2 0.011 15.9 0.0 2.6 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 CAM40864.1 - 0.11 12.8 0.0 0.52 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Tyr-DNA_phospho PF06087.12 CAM40865.1 - 2.6e-67 227.6 0.0 3.8e-67 227.0 0.0 1.2 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase OGFr_III PF04680.13 CAM40867.2 - 7e-188 601.2 365.8 3.4e-07 30.5 6.0 31.5 28 0 0 28 28 28 28 Opioid growth factor receptor repeat HTH_IclR PF09339.10 CAM40867.2 - 1.1e-10 41.1 53.8 2.5e+02 1.6 0.0 26.2 28 0 0 28 28 28 0 IclR helix-turn-helix domain RBD-FIP PF09457.10 CAM40867.2 - 3.3e-10 39.7 14.5 7.1e+02 0.2 0.0 21.0 28 0 0 28 28 28 0 FIP domain tRNA-synt_His PF13393.6 CAM40867.2 - 2.1e-05 24.0 23.4 1.5e+02 1.5 0.0 14.3 16 0 0 16 16 16 0 Histidyl-tRNA synthetase OGFr_III PF04680.13 CAM40868.2 - 1.6e-68 224.2 137.6 1.7e-07 31.5 6.0 11.6 12 0 0 12 12 12 10 Opioid growth factor receptor repeat Stb3 PF10330.9 CAM40868.2 - 1.3e-09 38.0 0.1 1.9e+02 2.2 0.0 9.9 10 0 0 10 10 10 0 Putative Sin3 binding protein TB PF00683.17 CAM40868.2 - 2.5e-09 36.7 1.1 1.5e+02 2.2 0.0 9.8 10 0 0 10 10 10 0 TB domain HTH_IclR PF09339.10 CAM40868.2 - 1.3e-06 28.1 14.7 1.3e+02 2.5 0.0 10.4 10 0 0 10 10 10 0 IclR helix-turn-helix domain RBD-FIP PF09457.10 CAM40868.2 - 1.1e-05 25.2 0.7 3.6e+02 1.2 0.0 8.8 10 0 0 10 10 10 0 FIP domain ChuX_HutX PF06228.13 CAM40868.2 - 0.0026 17.5 3.0 6.7e+02 0.0 0.0 8.2 10 0 0 10 10 10 0 Haem utilisation ChuX/HutX tRNA-synt_His PF13393.6 CAM40868.2 - 0.0058 15.9 12.1 72 2.5 0.0 7.5 8 0 0 8 8 8 0 Histidyl-tRNA synthetase DUF2437 PF10370.9 CAM40868.2 - 1.3 10.0 15.8 9.6e+02 0.8 0.0 9.4 10 0 0 10 10 10 0 Domain of unknown function (DUF2437) Ribosomal_S13_N PF08069.12 CAM40874.1 - 8.4e-25 86.6 1.8 1.6e-24 85.7 1.8 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 CAM40874.1 - 1.9e-13 50.4 1.1 3.2e-13 49.7 1.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 Acyl-CoA_ox_N PF14749.6 CAM40875.1 - 0.093 13.3 1.4 0.38 11.3 0.2 2.5 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal Med9 PF07544.13 CAM40876.1 - 0.0015 18.5 3.2 0.032 14.3 0.3 3.3 3 0 0 3 3 3 1 RNA polymerase II transcription mediator complex subunit 9 mTERF PF02536.14 CAM40876.1 - 0.012 14.6 0.0 0.039 12.9 0.0 1.8 3 0 0 3 3 3 0 mTERF DUF1664 PF07889.12 CAM40876.1 - 0.015 15.3 3.3 4.2 7.4 0.1 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) FAM76 PF16046.5 CAM40876.1 - 0.041 13.2 0.3 0.083 12.2 0.3 1.5 1 0 0 1 1 1 0 FAM76 protein NPV_P10 PF05531.12 CAM40876.1 - 0.089 13.3 1.5 40 4.8 0.1 3.8 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 CAM40876.1 - 0.1 11.9 6.9 0.4 10.0 1.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Apolipoprotein PF01442.18 CAM40876.1 - 0.11 12.4 16.6 0.45 10.4 3.2 2.8 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain EzrA PF06160.12 CAM40876.1 - 0.18 9.9 0.0 0.39 8.8 0.0 1.4 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Baculo_PEP_C PF04513.12 CAM40876.1 - 2.1 8.4 8.1 48 4.0 0.1 4.1 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus ADIP PF11559.8 CAM40876.1 - 4 7.5 8.1 10 6.2 0.6 3.3 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding HisKA_3 PF07730.13 CAM40876.1 - 5 7.7 9.6 42 4.8 0.0 4.4 3 1 0 3 3 3 0 Histidine kinase DUF4381 PF14316.6 CAM40877.1 - 0.096 12.9 0.1 0.23 11.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) EphA2_TM PF14575.6 CAM40877.1 - 0.48 11.3 9.6 1.7 9.6 0.0 3.8 3 2 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain LSM PF01423.22 CAM40878.1 - 1.3e-14 53.6 0.1 1.9e-14 53.1 0.1 1.2 1 0 0 1 1 1 1 LSM domain Zip PF02535.22 CAM40879.1 - 1.1e-35 123.5 17.4 4e-34 118.3 17.4 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter HPP PF04982.13 CAM40879.1 - 1.5 9.0 9.4 0.1 12.8 1.2 2.8 2 1 0 2 2 2 0 HPP family Coatomer_WDAD PF04053.14 CAM40880.1 - 6.6e-139 463.8 0.0 1.1e-138 463.0 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 CAM40880.1 - 2e-27 94.9 1.5 4.1e-07 30.6 0.0 6.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM40880.1 - 4.8e-08 33.2 0.0 2.5 8.5 0.0 6.6 4 3 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain TPR_8 PF13181.6 CAM40880.1 - 0.0061 16.7 0.3 0.19 12.0 0.0 3.1 1 1 2 3 3 3 1 Tetratricopeptide repeat Clathrin PF00637.20 CAM40880.1 - 0.046 13.6 0.5 1.7 8.5 0.0 2.6 1 1 2 3 3 3 0 Region in Clathrin and VPS TPR_2 PF07719.17 CAM40880.1 - 0.1 12.8 0.1 8.5 6.8 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 CAM40880.1 - 0.19 12.1 1.8 3.3 8.1 0.1 3.1 1 1 2 3 3 3 0 Tetratricopeptide repeat EF-hand_7 PF13499.6 CAM40882.1 - 3.4e-06 27.4 0.1 7.6e-05 23.1 0.0 2.9 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 CAM40882.1 - 0.0001 21.9 0.0 0.0058 16.5 0.0 3.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 CAM40882.1 - 0.00016 21.0 0.0 0.00043 19.7 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 CAM40882.1 - 0.0027 17.1 0.0 0.04 13.5 0.0 2.7 2 0 0 2 2 2 1 EF hand Bac_A_amyl_C PF18612.1 CAM40882.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial Alpha amylase C-terminal domain Ribosomal_L44 PF00935.19 CAM40883.1 - 1.2e-31 109.0 9.1 1.7e-31 108.5 9.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 CCT_2 PF09425.10 CAM40885.1 - 0.12 12.2 5.2 0.25 11.3 2.7 2.4 2 0 0 2 2 2 0 Divergent CCT motif ABC_tran PF00005.27 CAM40886.1 - 1.6e-17 64.3 0.0 2.6e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CAM40886.1 - 0.0028 17.1 0.0 0.05 13.0 0.0 1.9 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CAM40886.1 - 0.0058 16.3 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Cys_Met_Meta_PP PF01053.20 CAM40886.1 - 0.012 14.1 0.0 0.027 13.0 0.0 1.5 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme AAA_16 PF13191.6 CAM40886.1 - 0.035 14.5 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 CAM40886.1 - 0.059 12.9 0.2 0.34 10.5 0.0 2.3 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 CAM40886.1 - 0.21 11.7 0.1 0.55 10.3 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase FA_desaturase PF00487.24 CAM40887.1 - 3.4e-24 86.1 31.8 3.4e-24 86.1 31.8 1.9 1 1 1 2 2 2 2 Fatty acid desaturase CAF-1_p150 PF11600.8 CAM41400.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CENP-T_C PF15511.6 CAM41401.1 - 2.9e-06 27.3 0.1 4.8e-06 26.7 0.0 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CAM41401.1 - 0.00054 20.2 0.3 0.00082 19.6 0.0 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 CAM41401.1 - 0.00056 20.0 0.1 0.00088 19.4 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 CAM41401.1 - 0.0011 18.9 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 CAM41401.1 - 0.0044 17.4 1.5 0.0085 16.5 1.5 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CAM41401.1 - 0.05 13.7 0.0 0.066 13.3 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 CAM41404.1 - 1.9e-05 24.8 0.1 3e-05 24.1 0.0 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CAM41404.1 - 0.002 18.3 0.3 0.003 17.8 0.0 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 CAM41404.1 - 0.0025 17.9 0.1 0.004 17.3 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 CAM41404.1 - 0.0046 16.9 0.0 0.0054 16.7 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 CAM41404.1 - 0.011 16.1 1.5 0.022 15.1 1.5 1.5 1 1 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CAM41404.1 - 0.15 12.1 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit PCP_red PF08369.10 CAM41404.1 - 0.33 11.2 1.6 1.4 9.2 0.1 2.4 2 1 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit Cyt-b5 PF00173.28 CAM41406.1 - 9e-44 147.5 0.2 1.3e-20 73.3 0.0 2.1 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain EFP_N PF08207.12 CAM41406.1 - 0.017 15.2 0.0 2.3 8.3 0.0 2.4 2 0 0 2 2 2 0 Elongation factor P (EF-P) KOW-like domain SPT_ssu-like PF11779.8 CAM41406.1 - 0.067 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Small subunit of serine palmitoyltransferase-like PAC4 PF16093.5 CAM41407.1 - 0.054 13.7 0.0 0.089 13.0 0.0 1.4 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 Xpo1 PF08389.12 CAM41411.2 - 8.4e-25 87.6 1.9 6.9e-23 81.4 0.1 3.6 3 0 0 3 3 3 1 Exportin 1-like protein CNOT11 PF10155.9 CAM41411.2 - 0.025 14.8 0.1 0.16 12.2 0.1 2.4 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 11 UME PF08064.13 CAM41411.2 - 9.1 6.3 7.6 4.9 7.1 0.1 3.7 4 0 0 4 4 4 0 UME (NUC010) domain PI3_PI4_kinase PF00454.27 CAM41412.2 - 1.7e-42 146.0 0.0 2.7e-42 145.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 CAM41412.2 - 3.2e-08 33.2 1.1 6e-08 32.4 0.1 2.1 2 0 0 2 2 2 1 FATC domain SF3A2 PF16835.5 CAM41413.1 - 2.2e-22 79.2 0.0 3.5e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 CAM41413.1 - 0.00063 20.1 0.2 0.0015 18.9 0.2 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CAM41413.1 - 0.0041 17.4 0.2 0.0085 16.4 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AAA_25 PF13481.6 CAM41413.1 - 0.023 14.3 0.2 0.043 13.4 0.2 1.5 1 1 0 1 1 1 0 AAA domain Ank_2 PF12796.7 CAM41414.2 - 9.7e-12 45.3 0.2 2.6e-10 40.7 0.1 2.5 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CAM41414.2 - 2.4e-08 34.3 0.1 2.7e-05 24.6 0.1 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) zf-C3HC4_3 PF13920.6 CAM41414.2 - 4.1e-07 29.8 11.3 9.2e-07 28.6 11.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank_5 PF13857.6 CAM41414.2 - 0.00041 20.6 0.1 0.0047 17.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CAM41414.2 - 0.00082 19.7 0.2 0.013 16.0 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat zf-RING_2 PF13639.6 CAM41414.2 - 0.0035 17.6 13.5 0.011 16.1 13.5 1.9 1 0 0 1 1 1 1 Ring finger domain Ank PF00023.30 CAM41414.2 - 0.0036 17.7 0.9 0.033 14.6 0.1 2.9 3 0 0 3 3 3 1 Ankyrin repeat Galactosyl_T PF01762.21 CAM41415.1 - 0.013 15.4 0.1 0.11 12.4 0.0 2.5 4 0 0 4 4 4 0 Galactosyltransferase Focadhesin PF11229.8 CAM41415.1 - 0.083 11.1 0.1 0.13 10.5 0.1 1.1 1 0 0 1 1 1 0 Focadhesin Vps51 PF08700.11 CAM41417.2 - 9e-10 38.5 0.0 2.5e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 Vps51/Vps67 SRP14 PF02290.15 CAM41418.1 - 0.23 11.9 0.9 1.1 9.7 0.1 2.4 3 0 0 3 3 3 0 Signal recognition particle 14kD protein TPPII_N PF12583.8 CAM41418.1 - 6.9 7.3 12.0 5.3 7.6 4.0 2.7 3 0 0 3 3 3 0 Tripeptidyl peptidase II N terminal Galactosyl_T PF01762.21 CAM41420.2 - 0.069 13.0 0.2 0.35 10.6 0.0 2.1 2 0 0 2 2 2 0 Galactosyltransferase Galactosyl_T PF01762.21 CAM41421.1 - 0.031 14.1 0.1 0.31 10.8 0.0 2.6 3 0 0 3 3 3 0 Galactosyltransferase Galactosyl_T PF01762.21 CAM41422.1 - 0.039 13.8 0.3 0.19 11.5 0.0 2.2 2 0 0 2 2 2 0 Galactosyltransferase Galactosyl_T PF01762.21 CAM41423.2 - 0.0074 16.1 0.2 0.15 11.8 0.1 2.8 3 0 0 3 3 3 1 Galactosyltransferase Galactosyl_T PF01762.21 CAM41424.1 - 0.0048 16.7 0.4 0.036 13.9 0.0 2.6 2 1 0 2 2 2 1 Galactosyltransferase Galactosyl_T PF01762.21 CAM41425.2 - 0.00052 19.9 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 Galactosyltransferase GlcNAc PF11397.8 CAM41426.2 - 2e-139 465.0 0.0 3.1e-139 464.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) GlcNAc PF11397.8 CAM41427.1 - 3.3e-06 26.8 0.0 0.031 13.7 0.0 2.7 2 1 0 2 2 2 2 Glycosyltransferase (GlcNAc) Hexapep_loop PF18776.1 CAM41427.1 - 0.22 11.2 1.0 1.6 8.4 0.2 2.4 2 0 0 2 2 2 0 Hexapeptide repeat including loop Ras PF00071.22 CAM41428.1 - 7.8e-34 116.6 0.1 9e-34 116.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAM41428.1 - 8.8e-31 106.6 0.0 1.1e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAM41428.1 - 3.1e-11 43.0 0.0 3.7e-11 42.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CAM41428.1 - 0.00011 21.6 0.0 0.00013 21.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CAM41428.1 - 0.00017 21.1 0.0 0.0002 20.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CAM41428.1 - 0.0021 18.1 0.0 0.0029 17.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase TniB PF05621.11 CAM41428.1 - 0.032 13.7 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein AAA_7 PF12775.7 CAM41428.1 - 0.034 13.7 0.1 0.048 13.2 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 CAM41428.1 - 0.047 13.4 0.0 0.051 13.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain DLIC PF05783.11 CAM41428.1 - 0.058 12.2 0.0 0.061 12.2 0.0 1.0 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_16 PF13191.6 CAM41428.1 - 0.13 12.7 0.0 0.17 12.3 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain UPF0158 PF03682.13 CAM41429.1 - 0.027 14.4 0.0 0.031 14.3 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) Lectin_C_term PF18022.1 CAM41429.1 - 0.072 13.6 0.2 0.11 13.0 0.2 1.4 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin C-terminal domain Nudix_hydro PF18290.1 CAM41429.1 - 0.11 12.5 0.1 0.13 12.2 0.1 1.1 1 0 0 1 1 1 0 Nudix hydrolase domain Rhomboid PF01694.22 CAM41430.1 - 2.2e-09 37.5 8.7 9.7e-05 22.4 3.1 2.7 2 1 0 2 2 2 2 Rhomboid family Stevor PF17410.2 CAM41431.1 - 0.56 9.7 0.0 0.56 9.7 0.0 2.0 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame Pkinase PF00069.25 CAM41433.2 - 6.3e-47 160.1 0.0 3.3e-46 157.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM41433.2 - 1.4e-30 106.5 0.0 1.8e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM41433.2 - 1.8e-09 37.4 0.0 2.8e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CAM41433.2 - 7.6e-07 28.2 0.0 1.2e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CAM41433.2 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC2_membrane_3 PF12698.7 CAM41434.2 - 1e-62 212.3 30.0 5.1e-42 144.2 5.9 3.2 3 0 0 3 3 3 2 ABC-2 family transporter protein ABC_tran PF00005.27 CAM41434.2 - 1.8e-47 161.3 0.0 3.1e-22 79.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CAM41434.2 - 1e-11 45.2 3.0 0.0023 17.8 0.0 4.5 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CAM41434.2 - 1.2e-06 29.2 0.0 0.0018 18.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 CAM41434.2 - 1.5e-05 24.6 0.0 1.7 8.0 0.0 3.7 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CAM41434.2 - 5e-05 23.0 0.1 0.0091 15.7 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain MukB PF04310.12 CAM41434.2 - 0.00049 20.0 0.6 0.25 11.1 0.0 2.5 2 0 0 2 2 2 2 MukB N-terminal AAA_30 PF13604.6 CAM41434.2 - 0.002 17.9 0.0 1.3 8.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 CAM41434.2 - 0.0073 16.2 0.1 0.18 11.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase DUF4162 PF13732.6 CAM41434.2 - 0.013 16.2 0.0 1.2 9.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) AAA_27 PF13514.6 CAM41434.2 - 0.017 14.7 0.0 0.74 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 CAM41434.2 - 0.026 14.6 0.5 0.11 12.5 0.1 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 CAM41434.2 - 0.11 12.6 0.1 4.4 7.4 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 CAM41434.2 - 0.24 11.8 0.2 33 4.9 0.0 2.7 3 0 0 3 3 3 0 RNA helicase AAA_15 PF13175.6 CAM41434.2 - 0.3 10.7 0.0 5 6.7 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain SRP54 PF00448.22 CAM41434.2 - 0.56 9.8 2.2 3.2 7.3 0.1 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain SNAP PF14938.6 CAM41435.2 - 1.4e-11 44.4 12.3 7.4e-10 38.7 4.6 2.8 2 1 0 3 3 3 2 Soluble NSF attachment protein, SNAP DHR-2 PF06920.13 CAM41435.2 - 0.0092 14.7 0.0 0.014 14.1 0.0 1.2 1 0 0 1 1 1 1 Dock homology region 2 DUF1500 PF07389.12 CAM41435.2 - 0.027 14.5 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1500) UAA PF08449.11 CAM41436.2 - 5.8e-17 61.8 12.9 2.1e-10 40.3 2.5 3.7 4 0 0 4 4 4 2 UAA transporter family EamA PF00892.20 CAM41436.2 - 9.3e-06 25.9 3.0 9.3e-06 25.9 3.0 3.3 5 0 0 5 5 5 1 EamA-like transporter family PRIMA1 PF16101.5 CAM41436.2 - 0.039 14.0 0.1 0.039 14.0 0.1 5.0 4 1 0 4 4 4 0 Proline-rich membrane anchor 1 PUNUT PF16913.5 CAM41436.2 - 0.041 13.1 5.3 0.053 12.7 2.6 2.3 2 0 0 2 2 2 0 Purine nucleobase transmembrane transport MAP17 PF15807.5 CAM41436.2 - 0.047 13.9 0.0 1.4 9.2 0.0 2.4 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Pkinase PF00069.25 CAM41438.1 - 3.6e-56 190.4 0.0 4.5e-56 190.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM41438.1 - 4.5e-21 75.3 0.0 6.4e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CAM41438.1 - 1.2e-06 28.7 0.2 0.00045 20.2 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 CAM41438.1 - 0.0037 16.9 0.1 0.006 16.2 0.1 1.2 1 0 0 1 1 1 1 RIO1 family APH_6_hur PF04655.14 CAM41438.1 - 0.17 11.2 0.0 0.38 10.1 0.0 1.5 2 0 0 2 2 2 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase RPN6_N PF18055.1 CAM41439.1 - 8.2e-30 103.6 0.0 3.6e-29 101.5 0.0 2.2 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 CAM41439.1 - 1.1e-12 48.3 0.1 3e-12 47.0 0.1 1.8 1 0 0 1 1 1 1 PCI domain TPR_19 PF14559.6 CAM41439.1 - 0.028 14.9 12.7 0.66 10.5 0.2 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat DDRGK PF09756.9 CAM41439.1 - 0.034 13.7 0.2 0.034 13.7 0.2 2.0 2 0 0 2 2 2 0 DDRGK domain DUF885 PF05960.11 CAM41439.1 - 0.14 11.7 3.5 0.26 10.9 3.5 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF885) TPR_20 PF14561.6 CAM41439.1 - 1.4 9.3 13.1 2.6 8.5 0.0 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat FtsJ PF01728.19 CAM41440.2 - 3.9e-64 216.0 0.0 5.1e-64 215.6 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase UQ_con PF00179.26 CAM41441.1 - 7.7e-41 139.0 0.0 1.5e-40 138.1 0.0 1.4 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CAM41441.1 - 0.00069 19.3 0.0 0.00092 18.9 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B Med3 PF11593.8 CAM41441.1 - 7.1 5.7 6.2 9.4 5.3 6.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Zn-ribbon_8 PF09723.10 CAM41442.2 - 0.39 10.9 2.1 2.1 8.5 0.3 2.8 3 0 0 3 3 3 0 Zinc ribbon domain zf-C2H2_4 PF13894.6 CAM41442.2 - 7.5 7.7 7.9 3.5 8.7 0.9 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger Porin_3 PF01459.22 CAM41443.1 - 1.3e-06 28.1 0.0 1.7e-05 24.4 0.0 2.1 1 1 0 1 1 1 1 Eukaryotic porin DUF2890 PF11081.8 CAM41444.2 - 1.3e-05 25.4 0.5 1.3e-05 25.4 0.5 4.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2890) SLX9 PF15341.6 CAM41445.1 - 0.0046 17.4 9.7 0.037 14.4 9.7 2.4 1 1 0 1 1 1 1 Ribosome biogenesis protein SLX9 cNMPbd_u2 PF16643.5 CAM41446.1 - 9.3 6.7 9.8 4.9 7.6 1.6 3.1 2 0 0 2 2 2 0 Unstructured region on cNMP-binding protein Gly_kinase PF02595.15 CAM41447.2 - 2.7e-37 128.6 14.8 2.4e-18 66.3 2.2 6.7 6 1 0 6 6 6 5 Glycerate kinase family DUF2633 PF11119.8 CAM41447.2 - 0.85 9.6 4.7 2.1 8.3 4.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) DUF3327 PF11806.8 CAM41448.1 - 0.017 15.8 0.2 0.024 15.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3327) CDP-OH_P_transf PF01066.21 CAM41450.2 - 0.003 18.3 0.4 0.022 15.5 0.1 2.7 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Pkinase PF00069.25 CAM41453.1 - 1.6e-56 191.6 0.0 1e-50 172.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM41453.1 - 3.2e-35 121.7 0.0 4.2e-30 104.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CAM41453.1 - 0.00018 20.9 0.0 0.00084 18.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 CAM41453.1 - 0.00051 19.7 0.1 0.0013 18.4 0.0 1.6 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 CAM41453.1 - 0.0025 17.8 2.1 0.0025 17.7 0.1 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CAM41453.1 - 0.093 11.5 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 CAM41453.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1_like PF12832.7 CAM41453.1 - 1.6 7.5 5.4 2.5 6.9 5.4 1.2 1 0 0 1 1 1 0 MFS_1 like family RVT_1 PF00078.27 CAM41454.2 - 1.9e-21 76.6 0.0 2.9e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DZR PF12773.7 CAM41454.2 - 0.079 13.0 7.0 0.43 10.7 0.2 2.8 2 1 0 2 2 2 0 Double zinc ribbon UCH_1 PF13423.6 CAM41454.2 - 0.17 11.5 0.2 10 5.6 0.0 2.4 3 0 0 3 3 3 0 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L32p PF01783.23 CAM41454.2 - 0.28 11.5 2.0 3.5 7.9 0.8 3.3 2 1 0 2 2 2 0 Ribosomal L32p protein family FYVE PF01363.21 CAM41454.2 - 0.97 9.6 5.9 0.66 10.2 0.0 3.3 4 0 0 4 4 4 0 FYVE zinc finger zf-H2C2_2 PF13465.6 CAM41454.2 - 1.2 9.7 7.6 14 6.3 0.5 4.3 4 0 0 4 4 4 0 Zinc-finger double domain ASH PF15780.5 CAM41455.2 - 3.3e-06 27.2 2.7 0.25 11.5 0.0 5.8 5 0 0 5 5 5 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Snf7 PF03357.21 CAM41455.2 - 0.0027 17.3 5.4 0.0049 16.5 5.4 1.4 1 0 0 1 1 1 1 Snf7 TPR_1 PF00515.28 CAM41456.2 - 7.5e-07 28.7 0.7 7.5e-07 28.7 0.7 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 CAM41456.2 - 4.6e-06 26.2 1.3 0.00017 21.2 0.2 2.7 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.17 CAM41456.2 - 7.1e-06 25.8 0.7 7.1e-06 25.8 0.7 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CAM41456.2 - 5.1e-05 23.2 0.2 0.00017 21.5 0.2 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 CAM41456.2 - 0.043 14.3 5.4 2 9.0 0.4 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CAM41456.2 - 0.13 12.3 2.4 1.5 9.0 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 CAM41456.2 - 0.15 12.2 4.5 0.51 10.5 1.9 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 CAM41456.2 - 0.43 11.5 11.2 0.27 12.2 0.3 3.9 1 1 2 3 3 3 0 Tetratricopeptide repeat ARPC4 PF05856.12 CAM41457.1 - 1.3e-48 164.8 0.0 1.5e-48 164.6 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) SKA2 PF16740.5 CAM41458.1 - 0.0055 16.5 5.7 0.0055 16.5 5.7 2.5 1 1 1 2 2 2 1 Spindle and kinetochore-associated protein 2 Jnk-SapK_ap_N PF09744.9 CAM41458.1 - 0.0096 16.2 6.2 0.0096 16.2 6.2 2.4 1 1 1 2 2 2 1 JNK_SAPK-associated protein-1 Cauli_DNA-bind PF03310.13 CAM41458.1 - 0.15 12.1 1.0 0.28 11.2 1.0 1.5 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein FlaC_arch PF05377.11 CAM41458.1 - 0.87 10.0 7.9 0.18 12.3 2.0 2.8 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) Prominin PF05478.11 CAM41458.1 - 1.6 6.5 12.1 0.074 11.0 3.6 1.8 1 1 1 2 2 2 0 Prominin TACC_C PF05010.14 CAM41458.1 - 4.9 6.9 22.0 6.5 6.5 22.0 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Tup_N PF08581.10 CAM41458.1 - 5.7 7.3 16.4 0.9 9.9 8.3 2.6 2 1 0 2 2 2 0 Tup N-terminal TPR_MLP1_2 PF07926.12 CAM41458.1 - 7.6 6.6 27.1 0.034 14.2 5.1 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 CAM41458.1 - 8.5 6.6 25.8 1.1 9.5 1.6 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding WD40 PF00400.32 CAM41459.2 - 0.025 15.5 3.8 1.2 10.2 1.0 3.9 3 1 0 3 3 3 0 WD domain, G-beta repeat Adeno_E1B_55K PF01696.17 CAM41459.2 - 0.027 13.2 0.0 0.042 12.5 0.0 1.2 1 0 0 1 1 1 0 Adenovirus EB1 55K protein / large t-antigen Aldedh PF00171.22 CAM41460.1 - 7e-06 24.8 1.1 0.0011 17.6 0.0 2.4 2 1 0 2 2 2 2 Aldehyde dehydrogenase family LRR_4 PF12799.7 CAM41461.2 - 2.7e-08 34.0 0.1 2.2 8.8 0.0 7.7 9 0 0 9 9 9 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM41461.2 - 0.00018 21.2 0.1 2.4 8.0 0.0 5.2 5 0 0 5 5 5 2 Leucine rich repeat TruB_C_2 PF16198.5 CAM41461.2 - 0.042 14.0 0.5 5.6 7.2 0.1 3.4 3 0 0 3 3 3 0 tRNA pseudouridylate synthase B C-terminal domain Nop14 PF04147.12 CAM41463.2 - 8.6e-44 150.0 17.8 5.2e-31 107.7 0.3 3.2 2 1 1 3 3 3 3 Nop14-like family Mito_carr PF00153.27 CAM41464.1 - 2.8e-26 91.3 3.7 1.1e-12 47.7 0.2 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_M3 PF01432.20 CAM41466.1 - 4.8e-48 164.6 0.1 5.8e-48 164.3 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M3 MSSP PF03940.13 CAM41467.1 - 0.2 11.3 12.5 1.6 8.4 2.1 2.5 2 0 0 2 2 2 0 Male specific sperm protein HipA_C PF07804.12 CAM41467.1 - 0.29 10.8 0.7 1e+02 2.5 0.0 2.9 3 0 0 3 3 3 0 HipA-like C-terminal domain Form-deh_trans PF09163.11 CAM41467.1 - 1.6 8.6 6.4 3.8e+02 1.0 0.0 5.5 6 0 0 6 6 6 0 Formate dehydrogenase N, transmembrane DZR PF12773.7 CAM41468.1 - 0.021 14.8 0.2 0.06 13.4 0.2 1.7 1 0 0 1 1 1 0 Double zinc ribbon Peptidase_C98 PF15499.6 CAM41468.1 - 0.2 11.1 0.0 5.2 6.5 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase SPG4 PF17325.2 CAM41469.1 - 0.004 18.2 6.8 1.8 9.7 0.5 3.3 3 0 0 3 3 3 2 Stationary phase protein 4 DUF2469 PF10611.9 CAM41469.1 - 0.0069 16.9 0.0 35 5.0 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2469) DUF2459 PF09601.10 CAM41469.1 - 0.012 15.4 0.0 35 4.1 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2459) PTH2 PF01981.16 CAM41469.1 - 0.045 14.0 0.1 9 6.6 0.0 2.5 2 1 0 2 2 2 0 Peptidyl-tRNA hydrolase PTH2 ID PF18543.1 CAM41469.1 - 0.086 12.9 1.0 41 4.3 0.0 3.2 3 0 0 3 3 3 0 Intracellular delivery domain GSH-S_ATP PF02955.16 CAM41469.1 - 0.13 11.6 0.4 27 4.1 0.0 3.0 3 0 0 3 3 3 0 Prokaryotic glutathione synthetase, ATP-grasp domain DUF5621 PF18532.1 CAM41469.1 - 0.29 11.0 6.6 3 7.7 0.1 4.3 4 2 2 6 6 6 0 Domain of unknown function (DUF5621) RVT_1 PF00078.27 CAM41474.2 - 4.9e-17 62.2 0.0 8.1e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DZR PF12773.7 CAM41474.2 - 0.039 14.0 4.4 0.3 11.2 0.2 2.6 2 0 0 2 2 2 0 Double zinc ribbon HET PF06985.11 CAM41474.2 - 2 8.8 5.2 79 3.6 0.1 4.5 5 0 0 5 5 5 0 Heterokaryon incompatibility protein (HET) DZR PF12773.7 CAM41475.1 - 0.014 15.4 0.2 0.046 13.8 0.2 1.8 1 0 0 1 1 1 0 Double zinc ribbon Peptidase_C98 PF15499.6 CAM41475.1 - 0.22 11.0 0.0 4 6.8 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Chromo_shadow PF01393.19 CAM41476.1 - 0.0029 17.7 0.0 8.4 6.6 0.0 4.0 4 0 0 4 4 4 1 Chromo shadow domain PTH2 PF01981.16 CAM41476.1 - 0.0029 17.9 0.0 13 6.1 0.0 3.3 3 0 0 3 3 3 2 Peptidyl-tRNA hydrolase PTH2 4HBT PF03061.22 CAM41476.1 - 0.033 14.5 0.0 82 3.7 0.0 3.5 4 0 0 4 4 4 0 Thioesterase superfamily ID PF18543.1 CAM41476.1 - 0.21 11.6 1.6 6.1 6.9 0.1 3.2 3 0 0 3 3 3 0 Intracellular delivery domain PGM_PMM_I PF02878.16 CAM41479.1 - 1.5e-13 50.6 0.0 1.5e-09 37.6 0.0 2.4 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 CAM41479.1 - 7.7e-10 38.8 0.2 1.9e-09 37.5 0.2 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 CAM41479.1 - 0.0053 16.9 0.1 0.011 15.9 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 CAM41479.1 - 0.028 15.0 0.4 0.53 10.9 0.1 3.0 2 1 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II L27_1 PF09058.10 CAM41480.2 - 0.018 15.0 0.2 0.039 13.9 0.2 1.5 1 0 0 1 1 1 0 L27_1 E1-E2_ATPase PF00122.20 CAM41481.1 - 1.6e-47 161.4 0.6 1.6e-47 161.4 0.6 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CAM41481.1 - 3.2e-44 150.8 6.1 3.2e-44 150.8 6.1 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CAM41481.1 - 2.7e-20 73.6 0.5 2.6e-19 70.4 0.5 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CAM41481.1 - 2.8e-17 62.6 0.1 7.5e-17 61.2 0.1 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CAM41481.1 - 4.7e-14 51.8 0.6 9.2e-14 50.9 0.0 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CAM41481.1 - 1.6e-07 31.3 1.5 5.1e-06 26.4 0.9 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CAM41481.1 - 0.025 15.0 0.0 0.073 13.5 0.0 1.8 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CAM41482.1 - 2.2e-28 99.0 0.4 2.2e-28 99.0 0.4 1.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 CAM41482.1 - 3.2e-15 55.6 0.2 1.6e-14 53.3 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus ODAM PF15424.6 CAM41485.1 - 0.0097 15.5 0.5 0.015 14.9 0.5 1.2 1 0 0 1 1 1 1 Odontogenic ameloblast-associated family zf-CCCH_4 PF18044.1 CAM41485.1 - 6.4 6.7 8.2 1.7 8.5 4.3 2.2 2 0 0 2 2 2 0 CCCH-type zinc finger Arm_APC_u3 PF16629.5 CAM41486.1 - 0.065 12.8 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 Armadillo-associated region on APC Topo_C_assoc PF14370.6 CAM41488.1 - 1.4e-27 95.4 0.2 2e-27 94.9 0.2 1.2 1 0 0 1 1 1 1 C-terminal topoisomerase domain SPX PF03105.19 CAM41488.1 - 0.046 13.6 7.3 0.049 13.5 7.3 1.1 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 CAM41488.1 - 0.069 12.0 6.2 0.074 11.9 6.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CAM41488.1 - 0.075 11.6 6.2 0.082 11.5 6.2 1.1 1 0 0 1 1 1 0 Macoilin family DUF4614 PF15391.6 CAM41488.1 - 0.11 12.5 12.7 0.21 11.6 12.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF1980 PF09323.10 CAM41488.1 - 0.69 9.8 2.1 1.1 9.1 1.8 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) RAP1 PF07218.11 CAM41488.1 - 1.1 7.4 17.4 1.6 6.9 17.4 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Polyoma_lg_T_C PF06431.11 CAM41488.1 - 8.4 5.1 8.4 6.1 5.6 0.0 2.1 1 1 1 2 2 2 0 Polyomavirus large T antigen C-terminus Methyltransf_25 PF13649.6 CAM41489.1 - 0.00025 21.7 0.2 0.00063 20.4 0.2 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAM41489.1 - 0.006 16.4 0.0 0.0086 15.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAM41489.1 - 0.02 15.6 0.0 0.032 15.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CorA PF01544.18 CAM41490.1 - 0.028 13.7 0.3 0.031 13.6 0.3 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DASH_Dam1 PF08653.10 CAM41490.1 - 0.13 12.0 0.2 0.2 11.5 0.2 1.3 1 0 0 1 1 1 0 DASH complex subunit Dam1 FlaC_arch PF05377.11 CAM41490.1 - 0.17 12.3 0.5 0.32 11.4 0.5 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF3584 PF12128.8 CAM41492.1 - 0.015 12.9 10.7 0.021 12.4 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DAHP_synth_1 PF00793.20 CAM41492.1 - 0.035 13.0 0.1 0.055 12.3 0.1 1.2 1 0 0 1 1 1 0 DAHP synthetase I family eIF3_N PF09440.10 CAM41492.1 - 0.52 10.7 6.9 1.1 9.7 0.3 2.3 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain CP12 PF02672.15 CAM41492.1 - 2 9.2 0.0 2 9.2 0.0 3.4 4 0 0 4 4 4 0 CP12 domain CENP-H PF05837.12 CAM41493.1 - 0.23 11.9 6.8 0.26 11.7 2.7 2.7 3 0 0 3 3 3 0 Centromere protein H (CENP-H) KH_6 PF15985.5 CAM41494.1 - 3.5e-09 36.9 0.0 8.1e-09 35.7 0.0 1.7 1 1 0 1 1 1 1 KH domain Rib_hydrolayse PF02267.17 CAM41496.1 - 0.014 14.8 0.1 0.022 14.1 0.1 1.3 1 0 0 1 1 1 0 ADP-ribosyl cyclase VSP PF03302.13 CAM41503.1 - 0.00013 21.0 46.9 0.00063 18.7 12.7 6.9 1 1 4 6 6 6 4 Giardia variant-specific surface protein cEGF PF12662.7 CAM41503.1 - 0.094 12.7 0.5 0.094 12.7 0.5 9.8 9 1 0 9 9 9 0 Complement Clr-like EGF-like DUF5075 PF16825.5 CAM41504.1 - 0.00097 18.9 3.1 0.021 14.6 3.0 2.3 1 1 0 1 1 1 1 IGP family C-type lectin domain Toprim_4 PF13662.6 CAM41504.1 - 0.088 13.3 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 Toprim domain GRAM PF02893.20 CAM41505.1 - 6.8e-06 26.0 0.0 4.8e-05 23.2 0.0 2.4 2 1 0 2 2 2 1 GRAM domain PseudoU_synth_2 PF00849.22 CAM41506.2 - 4.9e-38 130.7 0.0 8.6e-38 129.9 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase TPR_2 PF07719.17 CAM41507.1 - 0.0021 18.0 3.1 6.1 7.2 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 CAM41507.1 - 0.0057 16.4 2.4 2.3 8.2 0.0 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CAM41507.1 - 0.051 13.9 8.6 0.15 12.4 0.1 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat MRP-L47 PF06984.13 CAM41508.2 - 2.2e-28 98.2 0.4 1.1e-27 96.0 0.1 2.2 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Tnp_22_trimer PF17489.2 CAM41508.2 - 0.02 14.8 0.8 0.047 13.7 0.8 1.6 1 0 0 1 1 1 0 L1 transposable element trimerization domain PRIMA1 PF16101.5 CAM41508.2 - 1.4 8.9 5.4 5.2 7.1 0.9 2.3 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 A_deaminase PF00962.22 CAM41509.1 - 2.7e-92 309.6 0.3 8.6e-67 225.8 0.0 3.6 4 0 0 4 4 4 2 Adenosine/AMP deaminase SLD3 PF08639.10 CAM41509.1 - 0.3 9.8 5.6 0.49 9.1 5.6 1.2 1 0 0 1 1 1 0 DNA replication regulator SLD3 CENP-H PF05837.12 CAM41509.1 - 8.4 6.9 8.1 20 5.6 8.1 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) ADH_N PF08240.12 CAM41510.1 - 9.5e-07 28.7 0.7 1.8e-06 27.8 0.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CAM41510.1 - 0.0059 16.6 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF4164 PF13747.6 CAM41511.1 - 0.003 17.8 0.1 0.0079 16.4 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4164) DUF1016_N PF17761.1 CAM41511.1 - 0.025 14.7 0.0 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 DUF1016 N-terminal domain Glyco_hydro_32N PF00251.20 CAM41512.2 - 2.6e-55 188.2 5.2 3.4e-55 187.8 5.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 CAM41512.2 - 3.4e-13 49.9 0.0 1e-12 48.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal PAN_1 PF00024.26 CAM41512.2 - 2.1e-05 24.4 1.0 4.2e-05 23.4 1.0 1.5 1 0 0 1 1 1 1 PAN domain DUF5074 PF16819.5 CAM41512.2 - 0.0056 16.7 0.6 2 8.5 0.0 3.2 3 1 0 3 3 3 2 Domain of unknown function (DUF5074) PAN_4 PF14295.6 CAM41512.2 - 0.0084 16.0 1.0 0.026 14.4 1.0 1.8 1 0 0 1 1 1 1 PAN domain RET_CLD3 PF17812.1 CAM41512.2 - 0.098 12.9 0.1 0.23 11.7 0.1 1.6 1 0 0 1 1 1 0 RET Cadherin like domain 3 RNB PF00773.19 CAM41513.2 - 2.6e-53 181.5 0.0 9.3e-52 176.4 0.0 2.1 2 0 0 2 2 2 2 RNB domain Angiomotin_C PF12240.8 CAM41513.2 - 0.19 11.2 0.6 1 8.8 0.0 2.1 2 0 0 2 2 2 0 Angiomotin C terminal Arf PF00025.21 CAM41514.1 - 6.8e-54 182.0 0.0 7.8e-54 181.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CAM41514.1 - 2.7e-15 56.6 0.0 3.5e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CAM41514.1 - 7.4e-14 51.7 0.0 8.2e-14 51.5 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CAM41514.1 - 1.2e-11 44.3 0.0 1.4e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CAM41514.1 - 1.8e-09 37.3 0.4 5.8e-06 25.7 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CAM41514.1 - 7.7e-09 35.2 0.0 9.8e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CAM41514.1 - 4.5e-07 29.9 0.0 5.9e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 CAM41514.1 - 0.0057 17.2 0.0 0.018 15.6 0.0 1.7 1 1 0 1 1 1 1 ABC transporter GTP_EFTU PF00009.27 CAM41514.1 - 0.0073 15.9 0.0 0.045 13.3 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Urocanase_N PF17391.2 CAM41514.1 - 0.03 14.0 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 Urocanase N-terminal domain cobW PF02492.19 CAM41514.1 - 0.15 11.6 0.1 0.66 9.5 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 CAM41514.1 - 0.16 11.8 0.1 0.23 11.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CAM41514.1 - 0.18 11.5 0.2 0.34 10.6 0.2 1.4 2 0 0 2 2 2 0 AAA ATPase domain zf-MYND PF01753.18 CAM41515.1 - 0.00026 21.0 9.4 0.00087 19.3 9.4 2.0 1 0 0 1 1 1 1 MYND finger PhyH PF05721.13 CAM41517.1 - 2.2e-43 149.0 0.0 3e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) RVT_1 PF00078.27 CAM41518.1 - 2e-11 43.8 0.0 2.1e-05 24.1 0.0 2.5 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CAM41519.1 - 2.4e-11 43.6 0.0 2.2e-05 24.1 0.0 2.5 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Shisa PF13908.6 CAM41520.1 - 0.00011 22.5 0.4 0.00029 21.1 0.1 1.8 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator CCSMST1 PF15013.6 CAM41520.1 - 0.00095 19.3 0.1 0.0022 18.1 0.1 1.6 1 0 0 1 1 1 1 CCSMST1 family FAM163 PF15069.6 CAM41520.1 - 0.032 14.7 0.1 0.073 13.5 0.1 1.6 1 0 0 1 1 1 0 FAM163 family FixS PF03597.15 CAM41520.1 - 0.035 13.8 0.0 0.035 13.8 0.0 1.8 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type DUF3357 PF11837.8 CAM41520.1 - 0.04 14.4 0.8 0.31 11.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) EphA2_TM PF14575.6 CAM41520.1 - 0.12 13.3 0.1 0.12 13.3 0.1 2.0 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMIE PF16038.5 CAM41520.1 - 1 9.2 6.3 2 8.3 6.3 1.3 1 0 0 1 1 1 0 TMIE protein ANAPC10 PF03256.16 CAM41521.1 - 8.4e-53 178.8 0.1 5.2e-52 176.2 0.1 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) TPR_1 PF00515.28 CAM41523.1 - 1.7e-10 40.3 0.7 0.00032 20.4 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CAM41523.1 - 5.4e-08 32.4 10.3 2.8e-05 23.9 0.2 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 CAM41523.1 - 1.1e-06 28.4 0.6 0.0077 16.4 0.0 3.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CAM41523.1 - 5.3e-06 26.8 1.1 0.0041 17.8 0.0 5.8 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 CAM41523.1 - 9.8e-06 25.2 4.3 0.0085 15.8 0.4 2.6 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.6 CAM41523.1 - 0.0082 16.4 13.3 0.33 11.3 0.1 5.3 4 1 2 6 6 6 2 Tetratricopeptide repeat SNAP PF14938.6 CAM41523.1 - 0.026 13.9 6.2 0.057 12.8 0.8 2.6 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_9 PF13371.6 CAM41523.1 - 0.033 14.3 8.0 0.59 10.3 0.3 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 CAM41523.1 - 0.041 13.6 0.1 0.041 13.6 0.1 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat-like domain COMMD1_N PF17221.3 CAM41523.1 - 0.079 13.3 2.4 3.8 7.9 0.2 2.8 2 1 1 3 3 3 0 COMMD1 N-terminal domain ChAPs PF09295.10 CAM41523.1 - 0.095 11.7 0.2 0.16 11.0 0.2 1.4 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.6 CAM41523.1 - 0.14 12.8 3.7 1.6 9.6 0.1 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 CAM41523.1 - 0.41 11.2 0.2 0.41 11.2 0.2 4.7 5 2 0 5 5 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 CAM41523.1 - 0.7 10.1 4.0 1.9 8.7 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 CAM41523.1 - 1.9 9.0 7.2 13 6.2 0.1 3.1 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation Pkinase PF00069.25 CAM41525.2 - 1.1e-40 139.6 0.0 1.5e-21 77.0 0.0 4.8 4 1 0 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.17 CAM41525.2 - 1.2e-32 113.2 0.1 7.1e-17 61.6 0.0 4.2 4 0 0 4 4 4 4 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAM41525.2 - 0.00026 19.9 0.0 0.00073 18.4 0.0 1.7 1 0 0 1 1 1 1 Fungal protein kinase Ku_N PF03731.15 CAM41525.2 - 0.17 11.6 0.7 0.42 10.3 0.1 1.9 2 0 0 2 2 2 0 Ku70/Ku80 N-terminal alpha/beta domain APH PF01636.23 CAM41525.2 - 0.19 11.6 3.0 0.78 9.6 0.0 2.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Peptidase_C2 PF00648.21 CAM41526.2 - 2.2e-55 187.8 0.0 3.2e-55 187.3 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 CAM41526.2 - 7.3e-33 113.0 0.1 1.6e-32 111.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Lyase_1 PF00206.20 CAM41527.1 - 1.9e-49 168.7 0.0 2.8e-49 168.2 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C PF08328.11 CAM41527.1 - 9.8e-46 154.6 0.0 1.8e-45 153.7 0.0 1.5 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal Thoc2 PF11732.8 CAM41527.1 - 0.078 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Transcription- and export-related complex subunit N_Asn_amidohyd PF14736.6 CAM41528.1 - 0.0089 15.2 1.2 0.32 10.1 0.0 3.6 3 1 1 4 4 4 1 Protein N-terminal asparagine amidohydrolase Apolipo_F PF15148.6 CAM41528.1 - 0.092 12.2 0.5 0.19 11.2 0.5 1.4 1 0 0 1 1 1 0 Apolipoprotein F Ribosomal_L5_C PF00673.21 CAM41529.1 - 8.3e-21 74.0 0.0 1.3e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CAM41529.1 - 9.4e-18 64.3 0.2 2.1e-16 60.0 0.0 2.3 2 0 0 2 2 2 1 Ribosomal protein L5 Arf PF00025.21 CAM41530.1 - 2.5e-60 202.9 0.0 2.9e-60 202.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CAM41530.1 - 5e-15 55.8 0.0 6.8e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CAM41530.1 - 1.7e-13 50.4 0.0 2e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CAM41530.1 - 8e-12 45.1 0.0 9.8e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CAM41530.1 - 5.3e-11 42.3 0.3 4.8e-08 32.5 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CAM41530.1 - 5.6e-06 25.9 0.0 7.4e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region 6PF2K PF01591.18 CAM41530.1 - 9.1e-05 21.9 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase MMR_HSR1 PF01926.23 CAM41530.1 - 0.00025 21.1 0.0 0.00035 20.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 CAM41530.1 - 0.014 15.4 0.2 0.13 12.2 0.2 2.0 1 1 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 CAM41530.1 - 0.082 13.1 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CAM41530.1 - 0.09 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin SRP54 PF00448.22 CAM41530.1 - 0.22 11.1 0.2 0.34 10.5 0.2 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Rbx_binding PF18113.1 CAM41531.1 - 0.063 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Rubredoxin binding C-terminal domain Laps PF10169.9 CAM41531.1 - 0.24 12.0 7.3 1.1 9.9 2.6 2.6 2 0 0 2 2 2 0 Learning-associated protein PAP_assoc PF03828.19 CAM41532.2 - 0.00011 22.3 0.0 0.00021 21.5 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CAM41532.2 - 0.00013 22.2 0.0 0.0003 21.0 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 CAM41532.2 - 0.0051 16.9 0.0 0.0096 16.0 0.0 1.4 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Ank_4 PF13637.6 CAM41534.1 - 8.4e-21 74.1 1.3 8.7e-07 29.4 0.0 5.7 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 CAM41534.1 - 2.7e-20 72.7 2.9 6.7e-08 33.0 0.0 4.7 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 CAM41534.1 - 1.1e-16 60.4 9.6 2.7e-06 27.6 0.0 6.6 6 1 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 CAM41534.1 - 5.7e-16 58.4 8.7 9.8e-10 38.5 0.1 5.2 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CAM41534.1 - 1.1e-15 56.2 4.6 4.6e-05 23.5 0.0 6.5 7 0 0 7 7 7 3 Ankyrin repeat DHHC PF01529.20 CAM41534.1 - 2.8e-15 56.6 1.3 2.8e-15 56.6 1.3 2.8 3 0 0 3 3 3 1 DHHC palmitoyltransferase UCR_Fe-S_N PF10399.9 CAM41535.1 - 0.19 11.1 4.3 0.39 10.1 2.8 2.4 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal TPR_19 PF14559.6 CAM41537.1 - 2.6e-37 127.1 54.8 1.9e-07 31.5 1.1 16.3 9 5 8 17 17 17 12 Tetratricopeptide repeat TPR_2 PF07719.17 CAM41537.1 - 3.4e-28 95.5 43.2 0.00058 19.8 0.4 19.0 22 0 0 22 22 20 5 Tetratricopeptide repeat TPR_16 PF13432.6 CAM41537.1 - 4.1e-25 88.2 61.7 2.1e-09 37.9 3.9 13.5 13 2 2 15 15 13 7 Tetratricopeptide repeat TPR_8 PF13181.6 CAM41537.1 - 4.9e-25 85.6 16.8 0.0021 18.2 0.1 13.6 15 0 0 15 15 14 5 Tetratricopeptide repeat TPR_1 PF00515.28 CAM41537.1 - 4.7e-21 73.7 29.7 0.00025 20.7 0.7 13.6 16 0 0 16 16 15 4 Tetratricopeptide repeat TPR_14 PF13428.6 CAM41537.1 - 5.5e-19 67.3 89.2 0.00011 22.7 0.1 22.0 13 7 13 26 26 24 6 Tetratricopeptide repeat TPR_7 PF13176.6 CAM41537.1 - 4.2e-14 51.4 24.9 0.04 13.9 0.0 12.5 13 0 0 13 13 11 4 Tetratricopeptide repeat TPR_12 PF13424.6 CAM41537.1 - 1.4e-11 44.5 68.8 0.00036 20.8 0.2 16.4 14 5 2 16 16 14 5 Tetratricopeptide repeat TPR_4 PF07721.14 CAM41537.1 - 3.1e-08 33.5 41.8 0.038 14.6 0.1 13.3 13 0 0 13 13 11 2 Tetratricopeptide repeat TPR_17 PF13431.6 CAM41537.1 - 1.2e-07 31.6 12.8 0.76 10.3 0.0 10.6 11 1 0 11 11 10 1 Tetratricopeptide repeat TPR_6 PF13174.6 CAM41537.1 - 8.1e-07 29.3 67.7 1.3 9.8 0.0 19.1 22 0 0 22 22 19 2 Tetratricopeptide repeat NARP1 PF12569.8 CAM41537.1 - 9.9e-07 28.0 3.7 0.54 9.1 0.0 6.3 6 2 1 7 7 7 2 NMDA receptor-regulated protein 1 TPR_11 PF13414.6 CAM41537.1 - 4.3e-06 26.3 21.3 2.6 7.8 0.0 10.6 13 0 0 13 13 13 4 TPR repeat ANAPC3 PF12895.7 CAM41537.1 - 5e-06 26.7 32.1 0.072 13.3 0.5 10.2 8 3 2 10 10 10 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 CAM41537.1 - 3.3e-05 23.2 37.1 0.00035 19.9 1.8 7.4 5 1 2 7 7 7 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 CAM41537.1 - 0.00011 21.9 24.5 0.038 13.6 0.9 7.3 7 3 1 8 8 8 3 Bacterial type III secretion protein (HrpB1_HrpK) TPR_10 PF13374.6 CAM41537.1 - 0.0034 17.2 0.5 0.057 13.3 0.0 11.7 13 0 0 13 13 11 2 Tetratricopeptide repeat PPR PF01535.20 CAM41537.1 - 0.013 15.7 2.0 1.9 8.9 0.0 5.0 5 0 0 5 5 3 0 PPR repeat SNAP PF14938.6 CAM41537.1 - 0.029 13.8 21.0 1.2 8.5 4.2 5.9 5 1 0 6 6 6 0 Soluble NSF attachment protein, SNAP MIT PF04212.18 CAM41537.1 - 0.12 12.4 5.5 20 5.4 0.1 4.6 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain ChAPs PF09295.10 CAM41537.1 - 1.1 8.1 6.5 0.4 9.6 0.1 2.9 4 0 0 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) Coatomer_E PF04733.14 CAM41537.1 - 9.6 5.5 10.4 7.3 5.9 0.0 4.1 6 0 0 6 6 6 0 Coatomer epsilon subunit Y_phosphatase2 PF03162.13 CAM41538.1 - 1e-51 174.8 0.0 1.4e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CAM41538.1 - 1.1e-09 38.7 0.0 1.3e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 CAM41538.1 - 0.0084 15.7 0.0 0.011 15.4 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CAM41538.1 - 0.047 13.5 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CAM41538.1 - 0.2 11.8 0.0 0.3 11.2 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate DENN PF02141.21 CAM41539.1 - 1.5e-08 34.8 0.3 4e-08 33.4 0.3 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain Spermine_synth PF01564.17 CAM41540.1 - 9e-48 162.2 0.0 1.7e-47 161.2 0.0 1.4 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 CAM41540.1 - 1.5e-15 56.8 0.0 2.6e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 CAM41540.1 - 3.2e-05 24.5 0.0 5.9e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAM41540.1 - 0.006 17.3 0.0 0.052 14.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAM41540.1 - 0.073 13.7 0.1 0.22 12.2 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain CRM1_repeat_2 PF18784.1 CAM41540.1 - 0.089 12.4 0.1 0.28 10.8 0.0 1.9 2 0 0 2 2 2 0 CRM1 / Exportin repeat 2 DUF1616 PF07760.11 CAM41541.1 - 0.017 14.5 0.3 0.026 13.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) DUF2207 PF09972.9 CAM41541.1 - 0.046 12.5 0.0 0.079 11.7 0.0 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) MMPL PF03176.15 CAM41541.1 - 0.98 8.3 4.6 6.3 5.6 2.7 2.3 2 0 0 2 2 2 0 MMPL family TFIID-18kDa PF02269.16 CAM41542.1 - 0.052 13.6 0.5 0.097 12.7 0.5 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Pox_EPC_I2-L1 PF12575.8 CAM41542.1 - 0.083 13.1 1.6 56 4.1 0.1 3.1 3 0 0 3 3 3 0 Poxvirus entry protein complex L1 and I2 zf-C3HC4_3 PF13920.6 CAM41543.1 - 8e-09 35.2 9.8 1.6e-08 34.3 9.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CAM41543.1 - 1.9e-07 30.8 9.8 3.7e-07 29.9 9.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CAM41543.1 - 1.2e-05 25.5 13.2 2.7e-05 24.4 13.2 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CAM41543.1 - 0.0027 17.5 10.4 0.0058 16.5 10.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF1449 PF07290.11 CAM41543.1 - 0.012 15.3 0.1 0.028 14.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) Baculo_IE-1 PF05290.11 CAM41543.1 - 0.12 12.3 3.8 0.22 11.5 3.8 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_UBOX PF13445.6 CAM41543.1 - 0.22 11.6 9.7 0.54 10.3 9.7 1.8 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.6 CAM41543.1 - 0.58 10.0 7.6 1.4 8.7 7.6 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain RskA PF10099.9 CAM41543.1 - 4.2 7.6 12.1 2.4 8.4 1.8 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Shisa PF13908.6 CAM41543.1 - 6.4 7.0 8.7 1.5 9.0 0.3 2.5 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator VSP PF03302.13 CAM41544.1 - 1.3e-09 37.5 143.7 0.00014 20.9 13.6 9.5 1 1 6 9 9 9 9 Giardia variant-specific surface protein cEGF PF12662.7 CAM41544.1 - 0.019 14.9 92.2 0.11 12.5 1.8 13.3 13 0 0 13 13 13 0 Complement Clr-like EGF-like TPR_8 PF13181.6 CAM41545.1 - 8.3e-06 25.6 0.6 0.00037 20.5 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat IQ PF00612.27 CAM41545.1 - 0.00082 19.0 0.5 0.0024 17.5 0.5 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif TPR_12 PF13424.6 CAM41545.1 - 0.0017 18.6 3.0 0.33 11.3 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CAM41545.1 - 0.0018 18.3 0.4 0.02 15.0 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_21 PF09976.9 CAM41545.1 - 0.0063 16.2 0.5 0.015 15.0 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat-like domain TPR_1 PF00515.28 CAM41545.1 - 0.0099 15.7 0.7 0.035 13.9 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 CAM41545.1 - 0.013 15.2 0.3 0.043 13.5 0.3 1.9 1 0 0 1 1 1 0 TPR repeat TAL_FSA PF00923.19 CAM41545.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Transaldolase/Fructose-6-phosphate aldolase DUF1840 PF08895.11 CAM41548.1 - 0.95 9.8 4.1 0.47 10.8 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Cmc1 PF08583.10 CAM41549.1 - 0.00077 19.4 1.8 0.0011 18.9 1.8 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.9 CAM41549.1 - 0.024 14.9 0.3 0.034 14.4 0.3 1.3 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DnaJ_C PF01556.18 CAM41550.1 - 2.1e-35 122.0 0.1 2.9e-35 121.5 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CAM41550.1 - 3.3e-21 75.2 0.7 6.4e-21 74.3 0.4 1.6 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CAM41550.1 - 4.8e-08 33.2 23.4 1e-07 32.2 23.4 1.6 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CAM41550.1 - 0.74 9.8 22.3 0.51 10.3 3.8 2.7 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Ribosomal_L16 PF00252.18 CAM41551.1 - 1.2e-39 135.3 0.3 1.6e-39 135.0 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DUF1490 PF07371.12 CAM41551.1 - 0.011 15.8 0.2 0.059 13.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1490) DUF3212 PF11486.8 CAM41551.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3212) zf-TRM13_CCCH PF11722.8 CAM41551.1 - 0.48 10.2 10.0 11 5.8 0.0 2.4 2 0 0 2 2 2 0 CCCH zinc finger in TRM13 protein NAC PF01849.18 CAM41552.1 - 2.1e-13 50.0 0.2 2.1e-13 50.0 0.2 2.0 2 0 0 2 2 2 1 NAC domain Myc_N PF01056.18 CAM41552.1 - 0.028 14.3 2.3 0.032 14.2 2.3 1.1 1 0 0 1 1 1 0 Myc amino-terminal region PGA2 PF07543.12 CAM41552.1 - 0.076 13.0 3.2 0.46 10.5 0.9 2.0 2 0 0 2 2 2 0 Protein trafficking PGA2 KptA_kDCL PF18176.1 CAM41552.1 - 0.21 11.5 1.4 0.37 10.7 0.5 1.8 1 1 1 2 2 2 0 KptA in kinetoplastid DICER domain Ribosomal_60s PF00428.19 CAM41552.1 - 7.6 7.2 16.4 0.15 12.7 8.7 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein DnaJ PF00226.31 CAM41553.1 - 1.5e-18 66.7 0.1 2.2e-18 66.1 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Tmemb_185A PF10269.9 CAM41553.1 - 4.4e-10 39.7 1.5 1.8e-09 37.7 0.4 2.5 1 1 1 2 2 2 2 Transmembrane Fragile-X-F protein Pescadillo_N PF06732.11 CAM41555.1 - 2e-90 303.1 4.2 5.2e-90 301.7 4.2 1.6 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT_2 PF16589.5 CAM41555.1 - 8.1e-11 42.2 0.0 1.8e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 CAM41555.1 - 2.5e-06 27.7 0.0 7.2e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain BRCT PF00533.26 CAM41555.1 - 0.0001 22.6 0.0 0.00027 21.3 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Y_phosphatase2 PF03162.13 CAM41557.1 - 7.2e-53 178.5 0.0 9.5e-53 178.2 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CAM41557.1 - 0.0041 17.1 0.0 0.0065 16.5 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Rhomboid PF01694.22 CAM41558.1 - 1.4e-08 34.9 1.9 2.8e-08 33.9 1.9 1.4 1 0 0 1 1 1 1 Rhomboid family DuoxA PF10204.9 CAM41558.1 - 0.18 10.8 3.3 0.046 12.7 0.4 1.4 2 0 0 2 2 2 0 Dual oxidase maturation factor Ribosomal_L30 PF00327.20 CAM41559.1 - 5.2e-05 23.0 0.3 0.00021 21.1 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e DUF1387 PF07139.11 CAM41560.2 - 2 8.1 10.9 3.1 7.5 10.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Hid1 PF12722.7 CAM41560.2 - 5 5.1 11.4 6.5 4.7 11.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Macoilin PF09726.9 CAM41560.2 - 8 4.9 10.0 9.6 4.6 10.0 1.1 1 0 0 1 1 1 0 Macoilin family Pkinase PF00069.25 CAM41563.1 - 3.6e-38 131.4 0.0 6.8e-17 61.7 0.1 6.0 5 1 0 5 5 5 4 Protein kinase domain Pkinase_Tyr PF07714.17 CAM41563.1 - 9.5e-15 54.6 0.0 1.4e-08 34.3 0.1 4.1 4 0 0 4 4 4 3 Protein tyrosine kinase FHA PF00498.26 CAM41563.1 - 2.9e-08 33.9 0.0 1.9e-07 31.3 0.0 2.2 1 1 0 1 1 1 1 FHA domain Pkinase_fungal PF17667.1 CAM41563.1 - 0.088 11.6 0.0 0.22 10.3 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase ThiS PF02597.20 CAM41563.1 - 0.15 12.8 0.0 0.54 10.9 0.0 2.0 1 0 0 1 1 1 0 ThiS family DUF2076 PF09849.9 CAM41564.1 - 5.5e-06 26.6 9.8 7.3e-06 26.2 9.8 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 CAM41564.1 - 0.00049 20.2 0.9 0.0007 19.7 0.9 1.2 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 CAM41564.1 - 0.005 16.8 0.6 0.0082 16.1 0.6 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UQ_con PF00179.26 CAM41565.1 - 7.3e-46 155.3 0.0 8.2e-46 155.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 CAM41565.1 - 0.006 16.4 0.2 0.012 15.5 0.2 1.5 1 1 0 1 1 1 1 UEV domain Prok-E2_B PF14461.6 CAM41565.1 - 0.011 15.4 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Ax_dynein_light PF10211.9 CAM41566.2 - 1.2e-09 38.3 3.6 1.2e-09 38.3 3.6 2.7 4 0 0 4 4 4 1 Axonemal dynein light chain Nrap_D6 PF17407.2 CAM41566.2 - 0.082 13.1 0.0 5.9 7.1 0.0 2.4 2 0 0 2 2 2 0 Nrap protein domain 6 CesT PF05932.13 CAM41568.1 - 1.6e-09 38.0 0.0 3.6e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Tir chaperone protein (CesT) family PDZ_2 PF13180.6 CAM41568.1 - 6.2e-08 32.8 0.0 1.7e-06 28.2 0.1 2.6 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 CAM41568.1 - 1.5e-05 24.7 0.2 0.00015 21.6 0.1 2.5 2 0 0 2 2 2 1 PDZ domain DUF974 PF06159.13 CAM41570.1 - 1.9e-06 27.8 0.0 4.5e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF974) WASH_WAHD PF11945.8 CAM41571.1 - 7.3e-07 29.0 0.0 1.2e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 WAHD domain of WASH complex XRCC4 PF06632.12 CAM41571.1 - 3.1 6.6 5.2 5.6 5.7 5.2 1.3 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Ribosomal_L16 PF00252.18 CAM41572.1 - 1.2e-39 135.3 0.3 1.6e-39 135.0 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DUF1490 PF07371.12 CAM41572.1 - 0.011 15.8 0.2 0.059 13.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1490) DUF3212 PF11486.8 CAM41572.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3212) zf-TRM13_CCCH PF11722.8 CAM41572.1 - 0.48 10.2 10.0 11 5.8 0.0 2.4 2 0 0 2 2 2 0 CCCH zinc finger in TRM13 protein ADK PF00406.22 CAM41573.1 - 1.6e-38 132.2 0.0 1.9e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CAM41573.1 - 1.3e-28 100.2 0.0 1.6e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CAM41573.1 - 4.3e-06 27.3 0.0 8.3e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CAM41573.1 - 1.7e-05 25.0 0.0 5e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CAM41573.1 - 0.013 15.8 0.2 0.026 14.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain dNK PF01712.19 CAM41573.1 - 0.016 15.1 0.3 0.092 12.6 0.1 1.9 2 0 0 2 2 2 0 Deoxynucleoside kinase Cytidylate_kin PF02224.18 CAM41573.1 - 0.086 12.6 0.1 0.24 11.1 0.0 1.8 2 0 0 2 2 2 0 Cytidylate kinase SRP54 PF00448.22 CAM41573.1 - 0.13 11.8 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 CAM41573.1 - 0.15 12.4 0.0 0.94 9.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CAM41573.1 - 0.18 12.2 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain FYVE PF01363.21 CAM41575.1 - 1.9 8.7 4.9 0.24 11.6 0.4 1.8 2 0 0 2 2 2 0 FYVE zinc finger DZR PF12773.7 CAM41575.1 - 4.5 7.4 11.0 2.4 8.2 1.7 3.0 3 0 0 3 3 3 0 Double zinc ribbon SDA1 PF05285.12 CAM41577.1 - 4.7e-05 23.0 23.9 5.3e-05 22.8 23.9 1.2 1 0 0 1 1 1 1 SDA1 YL1 PF05764.13 CAM41577.1 - 0.00021 21.5 23.6 0.00034 20.8 23.6 1.4 1 0 0 1 1 1 1 YL1 nuclear protein Nop14 PF04147.12 CAM41577.1 - 0.00021 19.7 27.5 0.00036 18.9 27.5 1.3 1 0 0 1 1 1 1 Nop14-like family TFIIF_alpha PF05793.12 CAM41577.1 - 0.0041 15.8 24.3 0.0051 15.5 24.3 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Mpp10 PF04006.12 CAM41577.1 - 0.008 14.7 19.8 0.011 14.2 19.8 1.2 1 0 0 1 1 1 1 Mpp10 protein Zip PF02535.22 CAM41577.1 - 0.47 9.6 2.8 0.56 9.4 2.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PNISR PF15996.5 CAM41577.1 - 1.5 9.1 12.7 2.4 8.4 12.7 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR SAPS PF04499.15 CAM41577.1 - 1.8 7.2 9.2 2.6 6.8 9.2 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BUD22 PF09073.10 CAM41577.1 - 3.8 6.8 33.0 5.7 6.2 33.0 1.2 1 0 0 1 1 1 0 BUD22 Presenilin PF01080.17 CAM41577.1 - 9.5 4.9 6.2 11 4.7 6.2 1.1 1 0 0 1 1 1 0 Presenilin Voltage_CLC PF00654.20 CAM41578.2 - 2.1e-87 293.6 24.6 2.1e-87 293.6 24.6 1.7 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 CAM41578.2 - 1.3e-05 25.5 2.8 0.06 13.8 0.0 3.6 3 0 0 3 3 3 2 CBS domain TAT_signal PF10518.9 CAM41578.2 - 0.4 10.6 5.9 0.098 12.5 0.4 2.7 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence RRP36 PF06102.12 CAM41579.1 - 4.7e-30 104.7 9.4 1.2e-29 103.5 9.4 1.6 1 1 0 1 1 1 1 rRNA biogenesis protein RRP36 DUF1660 PF07874.11 CAM41579.1 - 0.15 12.5 1.3 0.3 11.6 1.3 1.4 1 0 0 1 1 1 0 Prophage protein (DUF1660) COPI_assoc PF08507.10 CAM41580.1 - 2.2e-12 47.1 10.1 3.3e-12 46.6 10.1 1.2 1 0 0 1 1 1 1 COPI associated protein Acyltransferase PF01553.21 CAM41581.1 - 4.1e-14 52.4 0.1 5.5e-14 51.9 0.1 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransferase PF01553.21 CAM41582.1 - 4e-14 52.4 0.0 7e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DUF3486 PF11985.8 CAM41582.1 - 0.044 14.2 3.3 0.086 13.3 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) Acyltransferase PF01553.21 CAM41583.1 - 2.4e-12 46.6 0.3 4.3e-12 45.8 0.0 1.5 2 0 0 2 2 2 1 Acyltransferase DUF3486 PF11985.8 CAM41583.1 - 0.046 14.1 3.3 0.092 13.2 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) ISAV_HA PF06215.11 CAM41585.1 - 0.16 11.1 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Infectious salmon anaemia virus haemagglutinin Tcf25 PF04910.14 CAM41586.1 - 2.6e-36 125.5 0.0 4.1e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TAF4 PF05236.14 CAM41586.1 - 0.005 16.6 6.4 0.01 15.6 6.4 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family eIF3_subunit PF08597.10 CAM41586.1 - 2.1 8.2 19.2 3.9 7.3 19.2 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Radial_spoke_3 PF06098.11 CAM41586.1 - 3.9 6.7 12.6 6.7 5.9 12.6 1.3 1 0 0 1 1 1 0 Radial spoke protein 3 RICTOR_phospho PF14665.6 CAM41587.1 - 0.0017 18.6 1.5 0.0065 16.8 1.5 2.0 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, phosphorylation-site DUF5446 PF17522.2 CAM41587.1 - 0.052 13.7 0.5 0.61 10.3 0.5 2.9 1 0 0 1 1 1 0 Family of unknown function (DUF5446) UpxZ PF06603.11 CAM41587.1 - 0.69 10.2 4.5 0.39 11.0 1.5 2.2 2 0 0 2 2 2 0 UpxZ family of transcription anti-terminator antagonists OsmC PF02566.19 CAM41590.1 - 0.014 15.8 2.4 0.023 15.2 0.1 2.4 2 0 0 2 2 2 0 OsmC-like protein Transglut_i_TM PF14400.6 CAM41590.1 - 0.45 10.6 6.6 0.19 11.8 2.7 2.3 1 1 0 2 2 2 0 Inactive transglutaminase fused to 7 transmembrane helices DUF1664 PF07889.12 CAM41590.1 - 7.9 6.5 11.6 0.19 11.7 2.9 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) SCO1-SenC PF02630.14 CAM41591.1 - 1.6e-44 151.1 0.0 2.4e-44 150.5 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 CAM41591.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 AhpC/TSA family Phage_T4_Ndd PF06591.11 CAM41593.1 - 0.031 14.0 0.0 0.044 13.6 0.0 1.1 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) FBPase PF00316.20 CAM41594.1 - 2e-58 197.0 0.0 2.5e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Methyltransf_21 PF05050.12 CAM41595.2 - 4e-11 43.2 0.0 1.3e-09 38.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase FkbM domain SpoIIIAH PF12685.7 CAM41595.2 - 0.15 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein Methyltransf_12 PF08242.12 CAM41595.2 - 0.16 12.8 0.0 0.36 11.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 CAM41595.2 - 0.16 11.5 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain RRM_1 PF00076.22 CAM41596.1 - 2.5e-13 49.6 0.0 1.4e-05 24.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CAM41596.1 - 7.4e-09 35.3 0.1 0.00051 19.6 0.1 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CAM41596.1 - 0.00025 20.8 0.2 0.0042 16.9 0.1 2.5 2 1 0 2 2 2 1 Occluded RNA-recognition motif CDC48_2 PF02933.17 CAM41596.1 - 0.0021 17.8 0.0 0.0045 16.7 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 RRM_8 PF11835.8 CAM41596.1 - 0.004 17.3 0.1 0.013 15.7 0.1 1.9 2 0 0 2 2 2 1 RRM-like domain DUF5399 PF17377.2 CAM41596.1 - 0.044 13.6 0.5 0.12 12.2 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5399) DUF2857 PF11198.8 CAM41597.1 - 0.15 11.8 2.1 0.45 10.3 2.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) CorA PF01544.18 CAM41597.1 - 3.2 7.0 5.6 6.1 6.1 0.5 2.4 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein PolyA_pol PF01743.20 CAM41598.1 - 1.1e-28 100.2 0.0 2.5e-28 99.0 0.0 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 CAM41598.1 - 3.1e-07 30.0 0.1 7.7e-07 28.8 0.1 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Tenui_N PF05733.11 CAM41598.1 - 0.19 11.2 0.1 0.35 10.4 0.1 1.3 1 0 0 1 1 1 0 Tenuivirus/Phlebovirus nucleocapsid protein LRR_6 PF13516.6 CAM41599.1 - 2.7e-05 23.9 0.0 1.4 9.2 0.0 3.9 4 0 0 4 4 4 2 Leucine Rich repeat LRR_8 PF13855.6 CAM41599.1 - 0.057 13.2 0.6 2.9 7.7 0.2 3.4 3 1 1 4 4 4 0 Leucine rich repeat LRR_4 PF12799.7 CAM41599.1 - 0.076 13.5 0.3 2.3 8.8 0.1 3.0 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CAM41599.1 - 0.076 13.6 0.0 1.1e+02 4.0 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich Repeat Pkinase PF00069.25 CAM41600.1 - 4.1e-26 91.9 0.0 5.1e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM41600.1 - 2.3e-16 59.9 0.1 3.7e-16 59.2 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAM41600.1 - 8.4e-07 28.1 0.1 1e-06 27.8 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CAM41600.1 - 0.0026 17.1 0.0 0.0044 16.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CAM41600.1 - 0.084 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CAM41600.1 - 0.14 11.1 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Gelsolin PF00626.22 CAM41601.2 - 0.65 9.9 4.2 0.18 11.7 0.2 2.2 2 0 0 2 2 2 0 Gelsolin repeat IBP39 PF11422.8 CAM41601.2 - 0.84 9.4 4.8 1.7 8.3 4.8 1.4 1 0 0 1 1 1 0 Initiator binding protein 39 kDa Actin PF00022.19 CAM41602.1 - 6.4e-67 225.9 0.0 7.7e-67 225.7 0.0 1.0 1 0 0 1 1 1 1 Actin VSP PF03302.13 CAM41603.1 - 8e-12 44.7 71.6 3.6e-05 22.8 13.1 5.5 1 1 5 6 6 6 6 Giardia variant-specific surface protein cEGF PF12662.7 CAM41603.1 - 1.4e-06 28.1 43.2 0.12 12.3 0.8 7.4 7 0 0 7 7 7 6 Complement Clr-like EGF-like GBP_PSP PF02425.15 CAM41603.1 - 2.5 7.8 25.1 8 6.2 3.1 5.3 4 0 0 4 4 4 0 Paralytic/GBP/PSP peptide VSP PF03302.13 CAM41604.2 - 2.2e-09 36.7 52.8 4.6e-06 25.7 13.6 3.4 1 1 1 3 3 3 3 Giardia variant-specific surface protein cEGF PF12662.7 CAM41604.2 - 1.6e-07 31.1 29.0 0.012 15.5 0.9 5.0 5 0 0 5 5 5 4 Complement Clr-like EGF-like zf-C2H2_11 PF16622.5 CAM41604.2 - 0.028 14.2 9.0 3.8 7.3 0.4 4.8 4 0 0 4 4 4 0 zinc-finger C2H2-type DUF1168 PF06658.12 CAM41607.1 - 0.00016 21.5 13.6 0.00019 21.2 13.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Cwf_Cwc_15 PF04889.12 CAM41607.1 - 0.0061 16.3 12.1 0.0068 16.2 12.1 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein CrtC PF07143.11 CAM41607.1 - 0.063 14.0 1.0 0.085 13.5 1.0 1.2 1 0 0 1 1 1 0 CrtC N-terminal lipocalin domain DUF4603 PF15376.6 CAM41607.1 - 0.55 7.6 10.6 0.69 7.2 10.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) DUF4692 PF15763.5 CAM41607.1 - 2.1 8.8 7.0 4.2 7.8 7.0 1.5 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) U1snRNP70_N PF12220.8 CAM41607.1 - 5.5 7.7 12.8 30 5.3 12.8 2.0 1 1 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal FAM60A PF15396.6 CAM41607.1 - 7.5 6.5 11.5 7.6 6.5 10.6 1.4 1 1 0 1 1 1 0 Protein Family FAM60A Vir_act_alpha_C PF10400.9 CAM41607.1 - 8.3 7.2 10.6 7.3 7.4 6.3 2.7 1 1 1 2 2 2 0 Virulence activator alpha C-term T2SSM PF04612.12 CAM41609.2 - 0.013 15.6 0.1 0.019 15.1 0.1 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Shisa PF13908.6 CAM41609.2 - 1.3 9.2 8.4 0.16 12.2 3.2 1.9 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator VSP PF03302.13 CAM41610.1 - 8.1e-07 28.2 29.5 6.9e-06 25.2 13.3 2.1 1 1 1 2 2 2 2 Giardia variant-specific surface protein cEGF PF12662.7 CAM41610.1 - 0.00046 20.0 7.1 0.091 12.7 0.6 2.7 2 0 0 2 2 2 2 Complement Clr-like EGF-like GBP_PSP PF02425.15 CAM41610.1 - 2 8.1 12.3 0.41 10.3 1.6 2.7 3 0 0 3 3 3 0 Paralytic/GBP/PSP peptide VSP PF03302.13 CAM41611.1 - 3.1e-08 32.9 68.9 0.00029 19.8 11.7 4.1 1 1 3 4 4 4 4 Giardia variant-specific surface protein cEGF PF12662.7 CAM41611.1 - 5.4e-07 29.4 40.7 0.04 13.9 0.7 6.3 7 0 0 7 7 7 5 Complement Clr-like EGF-like zf-C2H2_11 PF16622.5 CAM41611.1 - 0.0018 18.0 15.1 3.8 7.3 0.4 6.1 5 0 0 5 5 5 3 zinc-finger C2H2-type ThiF PF00899.21 CAM41612.1 - 2.2e-38 132.0 0.0 3.8e-38 131.2 0.0 1.3 1 0 0 1 1 1 1 ThiF family ATG7_N PF16420.5 CAM41612.1 - 1.5e-26 93.7 0.0 2.2e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus Shikimate_DH PF01488.20 CAM41612.1 - 0.0002 21.4 0.0 0.0049 16.9 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 CAM41612.1 - 0.095 12.1 0.0 3.9 6.8 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Isy1 PF06246.12 CAM41613.1 - 1.3e-25 90.5 12.4 1.2e-24 87.3 12.4 2.3 1 1 0 1 1 1 1 Isy1-like splicing family DOT1 PF08123.13 CAM41614.1 - 1.3e-20 73.8 0.0 2e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 CAM41614.1 - 0.00017 22.2 0.0 0.00043 20.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CAM41614.1 - 0.0011 18.9 0.0 0.0019 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAM41614.1 - 0.0017 18.2 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAM41614.1 - 0.0025 18.4 0.0 0.0049 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CAM41614.1 - 0.014 14.7 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase AdoMet_MTase PF07757.13 CAM41614.1 - 0.079 13.3 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase MTS PF05175.14 CAM41614.1 - 0.082 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 CAM41614.1 - 0.12 13.1 0.0 0.21 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 CAM41614.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Adaptin_N PF01602.20 CAM41616.2 - 1.3e-84 284.7 9.4 1.7e-84 284.3 9.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CAM41616.2 - 1e-06 28.9 1.1 0.0015 18.6 0.0 2.6 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CAM41616.2 - 0.001 19.2 0.0 0.035 14.3 0.0 3.5 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 CAM41616.2 - 0.0012 19.2 0.2 0.53 10.7 0.0 3.7 4 0 0 4 4 4 1 HEAT repeats Nipped-B_C PF12830.7 CAM41616.2 - 0.058 13.3 1.2 3 7.8 0.0 2.9 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus Cytochrom_C1 PF02167.15 CAM41617.1 - 1.3e-76 257.2 0.0 1.4e-76 257.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Met_synt_B12 PF02965.17 CAM41620.1 - 1.8e-104 349.0 0.0 3.4e-104 348.1 0.0 1.5 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 CAM41620.1 - 9.2e-74 248.6 0.1 3.8e-73 246.6 0.1 2.1 2 0 0 2 2 2 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 CAM41620.1 - 2.7e-48 164.8 0.2 1.7e-45 155.6 0.2 2.8 2 0 0 2 2 2 2 Pterin binding enzyme B12-binding_2 PF02607.17 CAM41620.1 - 3.1e-24 85.2 0.8 9.9e-24 83.6 0.1 2.4 3 0 0 3 3 3 1 B12 binding domain B12-binding PF02310.19 CAM41620.1 - 1.3e-20 73.6 0.5 4.5e-20 71.9 0.3 2.1 2 0 0 2 2 2 1 B12 binding domain M16C_assoc PF08367.11 CAM41621.1 - 2.7e-24 85.7 0.1 5.4e-24 84.7 0.1 1.5 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 CAM41621.1 - 4.3e-21 75.7 0.0 2.4e-14 53.8 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CAM41621.1 - 4.1e-14 52.8 0.1 3.5e-11 43.3 0.0 2.7 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) Izumo-Ig PF16706.5 CAM41621.1 - 0.091 12.8 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain EF-hand_1 PF00036.32 CAM41622.1 - 1.5e-25 86.8 7.1 6.4e-07 28.5 0.1 5.0 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 CAM41622.1 - 2.6e-24 85.4 0.1 4.3e-07 30.3 0.2 4.2 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 CAM41622.1 - 1e-21 74.9 4.1 0.00015 21.4 0.0 5.4 7 0 0 7 7 7 4 EF-hand domain EF-hand_8 PF13833.6 CAM41622.1 - 1.8e-21 75.7 2.7 8.4e-06 25.6 0.0 4.3 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 CAM41622.1 - 2.9e-16 58.1 9.1 5.4e-06 25.7 0.0 4.5 5 0 0 5 5 5 3 EF hand EF-hand_4 PF12763.7 CAM41622.1 - 2.1e-06 27.6 0.1 0.088 12.8 0.0 3.6 3 1 1 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CAM41622.1 - 0.00011 22.4 0.6 1.5 9.2 0.0 3.6 3 1 1 4 4 4 2 EF-hand domain SPARC_Ca_bdg PF10591.9 CAM41622.1 - 0.00014 22.2 0.0 0.0045 17.3 0.0 2.7 3 0 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region p25-alpha PF05517.12 CAM41622.1 - 0.12 12.6 0.0 14 5.8 0.0 2.5 2 1 0 2 2 2 0 p25-alpha EF-hand_11 PF08976.11 CAM41622.1 - 0.15 12.9 0.5 55 4.7 0.0 3.6 3 1 1 4 4 4 0 EF-hand domain Sec7 PF01369.20 CAM41623.1 - 7.6e-36 123.5 0.0 1.5e-35 122.5 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 CAM41623.1 - 0.0022 17.9 1.0 0.047 13.6 0.0 3.2 2 1 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal tRNA_Me_trans PF03054.16 CAM41624.1 - 9.4e-44 149.6 0.0 1.1e-31 109.9 0.0 3.5 3 0 0 3 3 3 3 tRNA methyl transferase NAD_synthase PF02540.17 CAM41624.1 - 0.084 12.0 0.1 0.15 11.2 0.1 1.3 1 0 0 1 1 1 0 NAD synthase DUF1751 PF08551.10 CAM41625.1 - 0.00012 22.6 0.9 0.00012 22.6 0.9 2.4 2 2 1 3 3 3 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 CAM41625.1 - 0.036 14.1 1.4 0.069 13.2 1.1 1.8 1 1 0 1 1 1 0 Rhomboid family DUF747 PF05346.11 CAM41627.2 - 5.8e-70 236.3 1.6 8.3e-70 235.8 1.6 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family Pkinase PF00069.25 CAM41628.1 - 5.1e-49 167.0 0.0 8.4e-49 166.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM41628.1 - 1.8e-31 109.3 0.0 4.5e-31 108.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM41628.1 - 3.5e-05 23.3 0.0 6.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CAM41628.1 - 0.012 15.5 0.0 0.012 15.5 0.0 2.7 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CAM41628.1 - 0.059 12.1 0.0 0.18 10.6 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Pkinase PF00069.25 CAM41629.1 - 9.8e-50 169.4 0.0 6.4e-30 104.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM41629.1 - 2.6e-34 118.7 0.0 2.1e-20 73.1 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CAM41629.1 - 0.0028 17.0 0.0 0.2 10.9 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 CAM41629.1 - 0.0065 15.3 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CAM41629.1 - 0.15 11.4 0.3 0.34 10.2 0.3 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PTPA PF03095.15 CAM41631.1 - 7.7e-95 317.8 0.0 9.4e-95 317.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein PLDc_2 PF13091.6 CAM41632.1 - 3.6e-10 39.9 0.0 4.1e-05 23.5 0.0 3.3 2 2 0 2 2 2 2 PLD-like domain PLDc PF00614.22 CAM41632.1 - 2e-06 27.7 1.5 1.8e-05 24.7 0.1 2.9 2 1 0 2 2 2 1 Phospholipase D Active site motif HNF_C PF09354.10 CAM41632.1 - 0.047 14.8 0.1 0.047 14.8 0.1 2.5 2 0 0 2 2 2 0 HNF3 C-terminal domain CIAPIN1 PF05093.13 CAM41635.1 - 2.2e-14 53.7 16.9 7.6e-11 42.4 4.0 2.2 1 1 1 2 2 2 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Galactosyl_T PF01762.21 CAM41636.2 - 0.00077 19.3 0.5 0.0027 17.5 0.0 2.2 3 0 0 3 3 3 1 Galactosyltransferase T3SS_ExsE PF18286.1 CAM41636.2 - 0.04 13.8 0.3 0.15 12.1 0.3 1.9 1 0 0 1 1 1 0 Type III secretion system ExsE Pkinase PF00069.25 CAM41638.2 - 3.9e-39 134.6 0.0 3.2e-15 56.2 0.0 3.9 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CAM41638.2 - 6.3e-18 65.0 0.0 1.5e-11 44.1 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CAM41638.2 - 0.047 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 CAM41638.2 - 0.21 10.9 0.0 0.81 8.9 0.0 1.9 3 0 0 3 3 3 0 Kinase-like Kdo PF06293.14 CAM41638.2 - 0.22 10.9 0.0 0.38 10.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Homoserine_dh PF00742.19 CAM41639.1 - 3.7e-40 137.7 0.0 5.9e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase Peptidase_M20 PF01546.28 CAM41640.1 - 5.8e-33 114.3 0.0 1.4e-32 113.0 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CAM41640.1 - 3.9e-17 62.1 0.0 6.7e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain HECT PF00632.25 CAM41641.1 - 2.5e-86 289.9 0.0 4e-86 289.3 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) C1_2 PF03107.16 CAM41641.1 - 1.3e-06 28.6 8.2 2.7e-06 27.6 7.7 1.9 2 0 0 2 2 2 1 C1 domain ZZ PF00569.17 CAM41641.1 - 0.25 11.2 9.0 0.55 10.1 9.0 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type UPF0172 PF03665.13 CAM41642.1 - 1.3e-46 159.1 0.0 1.5e-46 158.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) LRR_4 PF12799.7 CAM41643.1 - 0.0014 19.0 0.2 0.049 14.1 0.4 2.4 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM41643.1 - 0.28 11.0 2.1 1.6 8.6 1.8 2.2 1 1 1 2 2 2 0 Leucine rich repeat DUF4887 PF16228.5 CAM41643.1 - 4 7.6 13.8 2.3 8.4 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4887) Flagellar_rod PF05149.12 CAM41644.1 - 9.8e-08 31.8 15.6 9.8e-08 31.8 15.6 2.2 2 0 0 2 2 2 1 Paraflagellar rod protein Halogen_Hydrol PF10112.9 CAM41644.1 - 0.15 12.0 2.8 10 6.1 0.1 2.9 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF2959 PF11172.8 CAM41644.1 - 5 7.2 11.9 0.76 9.9 4.6 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2959) ABA_GPCR PF12430.8 CAM41646.1 - 4.8e-29 101.4 0.9 4.8e-29 101.4 0.9 2.2 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 CAM41646.1 - 6.3e-07 29.4 0.1 2.5e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal EccE PF11203.8 CAM41646.1 - 4.7 7.6 6.4 0.59 10.5 1.8 1.8 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE NUDIX PF00293.28 CAM41647.1 - 3.3e-06 27.2 0.0 8.2e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain DEAD PF00270.29 CAM41648.2 - 2.7e-45 154.3 0.0 4.5e-45 153.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAM41648.2 - 3.4e-29 101.4 0.1 1.8e-28 99.1 0.1 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAM41648.2 - 0.0052 16.8 0.0 0.014 15.4 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 CAM41648.2 - 0.057 13.6 0.0 0.088 13.0 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain Ribosomal_60s PF00428.19 CAM41649.1 - 2 9.0 0.0 2 9.0 0.0 5.9 3 2 1 4 4 4 0 60s Acidic ribosomal protein DUF1674 PF07896.12 CAM41650.1 - 3.9e-14 52.9 0.0 6.1e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) zf-RING_UBOX PF13445.6 CAM41651.2 - 1.4e-06 28.2 7.6 3.4e-06 27.0 7.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CAM41651.2 - 2.2e-06 27.4 6.9 6.6e-06 25.9 6.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CAM41651.2 - 9.9e-06 25.8 7.9 9.9e-06 25.8 7.9 2.9 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CAM41651.2 - 1.1e-05 25.1 8.9 1.1e-05 25.1 8.9 2.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CAM41651.2 - 1.2e-05 25.0 5.8 1.2e-05 25.0 5.8 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CAM41651.2 - 5.2e-05 23.3 6.2 0.00015 21.9 6.2 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CAM41651.2 - 0.00021 21.1 5.8 0.00021 21.1 5.8 2.4 2 1 1 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CAM41651.2 - 0.00026 20.9 7.0 0.00026 20.9 7.0 2.3 2 0 0 2 2 1 1 zinc-RING finger domain zf-TRAF_2 PF15965.5 CAM41651.2 - 0.021 15.3 3.9 0.021 15.3 3.9 2.6 2 1 0 2 2 1 0 TRAF-like zinc-finger zf-RING_10 PF16685.5 CAM41651.2 - 0.069 13.3 6.2 0.21 11.7 6.2 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 Sina PF03145.16 CAM41651.2 - 0.13 12.2 3.6 0.23 11.4 3.6 1.3 1 0 0 1 1 1 0 Seven in absentia protein family zf-Nse PF11789.8 CAM41651.2 - 0.29 11.0 3.5 0.45 10.4 1.8 2.2 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Rav1p_C PF12234.8 CAM41652.2 - 7.2e-42 143.6 0.2 7.9e-40 136.9 0.3 2.1 1 1 0 1 1 1 1 RAVE protein 1 C terminal EamA PF00892.20 CAM41654.1 - 2.1e-16 60.3 31.2 6.3e-10 39.4 1.1 3.2 3 0 0 3 3 3 3 EamA-like transporter family SLC35F PF06027.12 CAM41654.1 - 4.3e-05 23.2 7.4 8.9e-05 22.1 7.4 1.5 1 0 0 1 1 1 1 Solute carrier family 35 UAA PF08449.11 CAM41654.1 - 0.00025 20.4 7.0 0.00048 19.4 7.0 1.4 1 0 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 CAM41654.1 - 0.0003 20.1 0.1 0.0003 20.1 0.1 2.2 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport CRT-like PF08627.10 CAM41654.1 - 0.49 9.3 7.2 0.34 9.8 1.0 2.2 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like SIN1_PH PF16979.5 CAM41655.1 - 1.6e-08 34.8 0.2 3.4e-08 33.7 0.2 1.4 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology MaoC_dehydratas PF01575.19 CAM41657.1 - 3.9e-21 74.9 0.0 6.5e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 CAM41657.1 - 1.3e-08 35.0 0.0 3.1e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase TAF8_C PF10406.9 CAM41657.1 - 0.044 14.4 0.6 0.094 13.3 0.6 1.6 1 0 0 1 1 1 0 Transcription factor TFIID complex subunit 8 C-term MaoC_dehydratas PF01575.19 CAM41658.1 - 1.5e-22 79.5 0.0 1.9e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 CAM41658.1 - 1.6e-11 44.5 0.0 3e-11 43.6 0.0 1.5 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase 4HBT PF03061.22 CAM41658.1 - 0.00012 22.3 0.0 0.00032 21.0 0.0 1.7 1 1 1 2 2 2 1 Thioesterase superfamily 4HBT_2 PF13279.6 CAM41658.1 - 0.071 13.6 0.0 0.1 13.1 0.0 1.3 1 1 0 1 1 1 0 Thioesterase-like superfamily Acyl-CoA_dh_N PF02771.16 CAM41660.1 - 3.3e-10 40.6 0.0 8.3e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CAM41660.1 - 7.2e-07 29.3 0.2 1.7e-06 28.1 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain RIBIOP_C PF04950.12 CAM41661.1 - 2.3e-92 309.5 0.0 4.8e-92 308.5 0.0 1.5 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CAM41661.1 - 3e-18 65.7 0.0 7.8e-18 64.3 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain MATalpha_HMGbox PF04769.12 CAM41661.1 - 0.015 14.6 0.1 0.035 13.4 0.1 1.5 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box Phage_integrase PF00589.22 CAM41662.1 - 9.7e-07 28.7 0.0 5.5e-06 26.3 0.0 2.4 2 0 0 2 2 2 1 Phage integrase family RVT_1 PF00078.27 CAM41662.1 - 0.0042 16.6 0.0 0.012 15.1 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A17 PF05380.13 CAM41662.1 - 0.006 16.6 0.1 0.057 13.4 0.0 2.3 1 1 1 2 2 2 1 Pao retrotransposon peptidase IATP PF04568.12 CAM41664.1 - 0.11 12.9 2.0 0.14 12.6 2.0 1.1 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP DHC_N2 PF08393.13 CAM41666.1 - 1.7e-45 155.8 0.0 6.2e-45 154.0 0.0 1.9 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_7 PF12775.7 CAM41666.1 - 2.9e-06 26.9 0.0 3.3e-05 23.5 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_8 PF12780.7 CAM41666.1 - 0.0088 15.4 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Tugs PF17840.1 CAM41666.1 - 0.046 13.9 0.2 0.57 10.4 0.0 2.9 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain AAA_6 PF12774.7 CAM41666.1 - 0.051 12.5 0.0 0.14 11.1 0.0 1.6 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region CENP-B_dimeris PF09026.10 CAM41666.1 - 0.17 12.3 0.1 22 5.5 0.0 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain CortBP2 PF09727.9 CAM41666.1 - 0.53 10.2 7.8 1.5 8.7 7.8 1.7 1 0 0 1 1 1 0 Cortactin-binding protein-2 CwsA PF10814.8 CAM41666.1 - 0.7 10.1 5.1 4.2 7.6 5.1 2.4 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA Golgin_A5 PF09787.9 CAM41666.1 - 2.4 7.5 9.0 0.74 9.2 5.3 1.9 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF3958 PF13125.6 CAM41666.1 - 2.9 8.1 4.5 0.95 9.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) DUF1180 PF06679.12 CAM41667.1 - 0.021 15.2 2.9 0.021 15.2 2.9 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1180) DUF4611 PF15387.6 CAM41667.1 - 0.32 11.2 4.2 0.67 10.2 4.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Serglycin PF04360.12 CAM41667.1 - 4.7 7.2 6.4 11 5.9 6.4 1.6 1 0 0 1 1 1 0 Serglycin NOA36 PF06524.12 CAM41667.1 - 4.9 6.4 5.5 7.2 5.8 5.5 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 CAM41667.1 - 5.1 5.1 6.1 7.1 4.6 6.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 CAM41667.1 - 5.3 6.7 10.6 0.62 9.7 5.6 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Ribosomal_L7Ae PF01248.26 CAM41668.1 - 2.5e-20 72.0 0.2 4.7e-20 71.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 CAM41668.1 - 5.7e-05 23.2 0.1 9.3e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 Ribosomal_L7Ae PF01248.26 CAM41669.1 - 2.5e-20 72.0 0.2 4.7e-20 71.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 CAM41669.1 - 5.7e-05 23.2 0.1 9.3e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 Sec20 PF03908.13 CAM41670.1 - 0.0021 17.9 1.7 0.0074 16.2 1.0 2.2 1 1 1 2 2 2 1 Sec20 V-SNARE_C PF12352.8 CAM41670.1 - 0.0035 17.6 1.4 0.012 15.9 1.4 1.8 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus TolA_bind_tri PF16331.5 CAM41670.1 - 0.22 11.6 8.3 0.081 13.0 4.7 2.2 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF5345 PF17280.2 CAM41670.1 - 0.3 11.1 1.8 0.39 10.7 0.3 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Atg14 PF10186.9 CAM41670.1 - 0.32 10.0 4.2 1.4 7.9 4.3 1.8 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CCDC-167 PF15188.6 CAM41670.1 - 8.5 6.8 13.4 6.2 7.2 6.3 3.0 2 2 0 2 2 2 0 Coiled-coil domain-containing protein 167 Mito_carr PF00153.27 CAM41671.1 - 3.7e-32 110.1 4.0 6.3e-13 48.5 0.3 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1615 PF07759.12 CAM41673.2 - 0.11 11.7 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1615) Ras PF00071.22 CAM41674.1 - 1e-54 184.5 0.0 1.2e-54 184.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAM41674.1 - 2.2e-28 98.9 0.0 3.1e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAM41674.1 - 6.5e-10 38.7 0.0 8.4e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CAM41674.1 - 0.00052 20.1 0.0 0.00077 19.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CAM41674.1 - 0.001 18.6 0.0 0.023 14.3 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CAM41674.1 - 0.017 14.5 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region CLP1_P PF16575.5 CAM41676.1 - 2.2e-29 102.6 0.0 7.1e-29 100.9 0.0 1.8 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 CAM41676.1 - 0.021 15.2 0.1 0.096 13.1 0.1 2.2 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 CAM41676.1 - 0.093 12.8 0.1 0.3 11.2 0.1 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 CAM41676.1 - 0.13 12.7 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 CAM41676.1 - 0.21 11.8 0.5 0.55 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain Sel1 PF08238.12 CAM41677.1 - 5.1e-21 74.6 38.7 7.7e-07 29.6 0.1 8.9 9 0 0 9 9 9 6 Sel1 repeat ETF_QO PF05187.13 CAM41678.1 - 2.3e-43 146.6 0.3 4.1e-43 145.8 0.3 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S FAD_binding_2 PF00890.24 CAM41678.1 - 5e-08 32.4 2.5 0.0014 17.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 CAM41678.1 - 1.5e-07 31.4 3.4 0.00031 20.5 1.1 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CAM41678.1 - 9.9e-07 28.9 0.1 3.7e-06 27.1 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CAM41678.1 - 1.2e-05 24.7 0.1 0.0082 15.4 0.3 2.2 2 0 0 2 2 2 2 Thi4 family Pyr_redox PF00070.27 CAM41678.1 - 0.0001 22.8 0.1 0.21 12.1 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CAM41678.1 - 0.00015 21.8 0.1 0.00028 20.9 0.1 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 CAM41678.1 - 0.00026 20.3 0.1 0.00043 19.6 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CAM41678.1 - 0.0014 17.4 0.4 0.0021 16.8 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.14 CAM41678.1 - 0.016 14.0 0.6 0.17 10.7 0.2 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.12 CAM41678.1 - 0.034 13.2 0.1 0.05 12.7 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 CAM41678.1 - 0.059 12.6 0.2 0.084 12.1 0.2 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CAM41678.1 - 0.069 12.4 1.2 0.086 12.1 0.2 1.7 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 CAM41678.1 - 0.084 12.2 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NPL PF17800.1 CAM41679.1 - 1e-11 45.3 0.0 2e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Nucleoplasmin-like domain Filament PF00038.21 CAM41681.1 - 0.00054 19.6 7.4 0.00054 19.6 7.4 3.5 2 1 1 3 3 3 1 Intermediate filament protein Fez1 PF06818.15 CAM41681.1 - 0.013 15.9 35.1 0.039 14.4 8.3 2.8 2 1 0 2 2 2 0 Fez1 eIF3m_C_helix PF18005.1 CAM41681.1 - 0.026 14.2 0.2 2.6 7.8 0.0 2.7 2 0 0 2 2 2 0 eIF3 subunit M, C-terminal helix Ycf54 PF10674.9 CAM41681.1 - 0.098 12.9 0.9 0.45 10.8 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2488) GBP PF02263.19 CAM41681.1 - 0.18 11.0 1.7 5 6.3 0.3 2.3 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain LPP PF04728.13 CAM41681.1 - 0.29 11.5 18.9 8.5 6.9 1.2 5.1 4 0 0 4 4 4 0 Lipoprotein leucine-zipper SHE3 PF17078.5 CAM41681.1 - 0.48 10.1 16.3 2.9 7.6 1.4 2.6 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 ERM PF00769.19 CAM41681.1 - 0.62 9.8 44.9 0.12 12.2 12.6 2.9 2 1 1 3 3 3 0 Ezrin/radixin/moesin family DUF4094 PF13334.6 CAM41681.1 - 1.9 9.0 11.2 19 5.8 0.1 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4094) DUF4407 PF14362.6 CAM41681.1 - 2.5 7.4 38.0 4.1 6.7 9.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) RNA_polI_A14 PF08203.11 CAM41681.1 - 3 8.6 10.8 0.08 13.7 1.1 3.3 3 0 0 3 3 3 0 Yeast RNA polymerase I subunit RPA14 HALZ PF02183.18 CAM41681.1 - 4.9 7.5 15.7 19 5.5 0.0 5.1 5 1 0 5 5 5 0 Homeobox associated leucine zipper HsbA PF12296.8 CAM41681.1 - 6.8 7.1 10.5 1.2 9.6 0.1 3.3 2 1 2 4 4 4 0 Hydrophobic surface binding protein A FAM76 PF16046.5 CAM41681.1 - 7.6 5.8 22.4 1.4 8.2 11.9 2.9 2 1 1 3 3 3 0 FAM76 protein GAS PF13851.6 CAM41681.1 - 7.9 5.8 35.9 0.16 11.3 7.2 4.0 5 0 0 5 5 5 0 Growth-arrest specific micro-tubule binding Cation_ATPase_C PF00689.21 CAM41682.1 - 2.4e-42 144.7 2.1 5.4e-42 143.6 2.1 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CAM41682.1 - 1.3e-31 109.5 0.4 7.7e-31 107.0 0.1 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CAM41682.1 - 4.9e-13 49.8 0.1 3.9e-11 43.6 0.1 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CAM41682.1 - 2.3e-12 46.4 0.0 4.5e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 CAM41682.1 - 9.8e-12 44.8 0.0 2.2e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CAM41682.1 - 9.7e-06 25.5 0.1 0.00046 20.0 0.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3935 PF13071.6 CAM41682.1 - 0.061 13.9 1.2 0.27 11.8 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3935) LptF_LptG PF03739.14 CAM41682.1 - 0.18 10.6 1.5 0.28 10.0 0.7 1.7 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG JAB PF01398.21 CAM41683.1 - 0.0099 15.9 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF4250 PF14056.6 CAM41683.1 - 0.37 10.8 2.3 1.7 8.6 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) Cation_ATPase_C PF00689.21 CAM41684.1 - 6.4e-42 143.3 4.5 8.7e-42 142.9 4.5 1.2 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CAM41684.1 - 7.1e-11 42.8 0.0 3.9e-10 40.4 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CAM41684.1 - 7.3e-08 32.4 0.0 1.4e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CAM41684.1 - 1e-06 28.7 0.0 0.00019 21.2 0.1 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF2162 PF09930.9 CAM41684.1 - 0.14 11.5 5.2 0.12 11.7 3.4 1.6 1 1 1 2 2 2 0 Predicted transporter (DUF2162) V-SNARE_C PF12352.8 CAM41686.1 - 1.4e-08 34.9 4.8 2.2e-08 34.2 4.8 1.2 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Prominin PF05478.11 CAM41686.1 - 0.027 12.5 0.4 0.033 12.2 0.4 1.0 1 0 0 1 1 1 0 Prominin Synaptobrevin PF00957.21 CAM41686.1 - 0.063 13.1 1.4 0.13 12.0 1.4 1.7 1 1 0 1 1 1 0 Synaptobrevin S4 PF01479.25 CAM41687.1 - 2.7e-13 49.4 0.3 5.8e-13 48.3 0.3 1.6 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 CAM41687.1 - 1.1e-07 32.6 0.2 2.3e-07 31.6 0.2 1.8 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain TyrRSs_C PF16714.5 CAM41687.1 - 0.019 14.7 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Tyrosyl-tRNA synthetase C-terminal domain Pkinase PF00069.25 CAM41688.2 - 4.6e-40 137.6 0.0 4.1e-26 91.9 0.0 3.6 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CAM41688.2 - 2.2e-22 79.6 0.0 9.2e-16 57.9 0.0 2.8 3 1 0 3 3 3 2 Protein tyrosine kinase NTP_transf_2 PF01909.23 CAM41689.1 - 0.0081 16.4 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 CAM41689.1 - 0.014 15.6 0.0 0.062 13.5 0.0 2.0 2 0 0 2 2 2 0 Cid1 family poly A polymerase PBP1_TM PF14812.6 CAM41689.1 - 4.5 7.7 9.5 1 9.8 4.1 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal EF-hand_1 PF00036.32 CAM41690.1 - 1.7e-26 89.7 9.2 8.5e-09 34.4 0.7 4.5 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 CAM41690.1 - 9.8e-25 86.8 1.4 1e-12 48.3 1.1 2.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CAM41690.1 - 3.8e-23 79.4 3.7 1.1e-09 37.4 0.1 4.5 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 CAM41690.1 - 1.4e-17 63.3 9.9 8.3e-12 44.8 1.1 3.7 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 CAM41690.1 - 6.6e-13 47.5 10.6 2e-05 23.9 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 CAM41690.1 - 2.2e-10 40.7 0.1 3.2e-05 24.2 0.0 2.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_4 PF12763.7 CAM41690.1 - 5.4e-06 26.3 0.8 0.016 15.2 0.0 2.6 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand SUB1_ProdP9 PF18213.1 CAM41690.1 - 0.002 17.9 0.1 0.0033 17.2 0.1 1.4 1 0 0 1 1 1 1 SUB1 protease Prodomain ProdP9 EF-hand_14 PF17959.1 CAM41690.1 - 0.0071 16.7 0.2 2 8.8 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain HEAT PF02985.22 CAM41692.1 - 8.3e-08 31.9 21.9 0.0074 16.5 0.6 10.7 11 0 0 11 11 11 2 HEAT repeat HEAT_2 PF13646.6 CAM41692.1 - 1.4e-07 31.8 23.3 0.00095 19.5 0.1 8.0 6 2 1 8 8 8 2 HEAT repeats CLASP_N PF12348.8 CAM41692.1 - 9.2e-06 25.4 0.1 0.052 13.1 0.0 3.2 2 0 0 2 2 2 2 CLASP N terminal Cnd1 PF12717.7 CAM41692.1 - 7.4e-05 22.8 0.0 0.014 15.4 0.0 3.7 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 DUF3437 PF11919.8 CAM41692.1 - 0.0006 19.7 1.0 0.0067 16.3 0.1 3.1 1 1 1 2 2 2 1 Domain of unknown function (DUF3437) HEAT_EZ PF13513.6 CAM41692.1 - 0.0037 17.7 3.9 0.013 16.0 1.0 10.7 7 4 3 12 12 11 3 HEAT-like repeat Vac14_Fab1_bd PF12755.7 CAM41692.1 - 0.032 14.8 0.1 0.63 10.7 0.0 3.4 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region IBN_N PF03810.19 CAM41692.1 - 0.038 13.9 0.0 0.23 11.4 0.0 2.5 2 0 0 2 2 2 0 Importin-beta N-terminal domain YdaT_toxin PF06254.11 CAM41692.1 - 0.065 13.8 0.2 3 8.5 0.0 3.3 2 0 0 2 2 2 0 Putative bacterial toxin ydaT RTP1_C1 PF10363.9 CAM41692.1 - 0.11 12.6 0.3 27 5.0 0.0 3.5 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_PBS PF03130.16 CAM41692.1 - 1.5 9.7 6.6 50 5.0 0.0 5.4 4 1 1 5 5 5 0 PBS lyase HEAT-like repeat MCD PF05292.11 CAM41693.2 - 3.6e-62 210.2 0.0 2e-40 139.0 0.0 3.1 2 1 0 2 2 2 2 Malonyl-CoA decarboxylase C-terminal domain DnaJ PF00226.31 CAM41695.1 - 1.9e-05 24.7 0.0 5.3e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 DnaJ domain His_Phos_1 PF00300.22 CAM41696.1 - 5.6e-29 101.2 0.1 3e-23 82.5 0.0 2.5 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) 6PF2K PF01591.18 CAM41696.1 - 1.1e-14 54.2 0.2 2.8e-10 39.9 0.0 3.3 3 0 0 3 3 3 3 6-phosphofructo-2-kinase AAA_33 PF13671.6 CAM41696.1 - 0.052 13.7 1.6 0.32 11.1 0.0 3.0 4 0 0 4 4 4 0 AAA domain DnaJ PF00226.31 CAM41697.1 - 9.5e-05 22.4 0.0 0.00021 21.3 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ PF00226.31 CAM41698.1 - 4.2e-07 30.0 0.1 9.6e-07 28.8 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 CAM41698.1 - 0.014 15.4 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 Pam16 Comm PF15957.5 CAM41698.1 - 0.082 13.3 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Commissureless BfiI_DBD PF18243.1 CAM41698.1 - 0.15 11.6 0.1 0.31 10.6 0.1 1.4 1 0 0 1 1 1 0 Metal-independent restriction enzyme BfiI DNA binding domain DUF1485 PF07364.12 CAM41699.1 - 0.054 12.8 1.5 0.07 12.4 1.5 1.2 1 0 0 1 1 1 0 Metallopeptidase family M81 UQ_con PF00179.26 CAM41702.1 - 2.8e-39 134.0 0.0 4.2e-39 133.4 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CAM41702.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B RRM_1 PF00076.22 CAM41706.1 - 0.028 14.2 0.1 3.5 7.5 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 CAM41708.1 - 4.1e-77 259.1 0.0 4.8e-77 258.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM41708.1 - 2.7e-39 135.0 0.0 3.2e-39 134.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM41708.1 - 2.1e-11 43.7 0.0 5.1e-09 35.9 0.0 2.1 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.14 CAM41708.1 - 0.00023 20.6 0.3 0.00038 19.9 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CAM41708.1 - 0.00032 19.8 0.2 0.00044 19.3 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CAM41708.1 - 0.005 16.8 0.2 0.19 11.6 0.1 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family IML1 PF12257.8 CAM41709.1 - 2e-37 128.9 0.0 2.3e-28 99.1 0.0 3.1 2 1 0 2 2 2 2 Vacuolar membrane-associated protein Iml1 Radial_spoke PF04712.12 CAM41710.1 - 1.1e-05 24.7 3.2 0.00045 19.3 1.9 2.7 2 1 0 2 2 2 2 Radial spokehead-like protein CENP-B_dimeris PF09026.10 CAM41710.1 - 0.014 15.7 2.2 0.023 15.1 2.2 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF3437 PF11919.8 CAM41711.1 - 2e-17 62.9 0.0 6.9e-17 61.1 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) NPL PF17800.1 CAM41715.1 - 2.7e-14 53.6 0.0 3.9e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Nucleoplasmin-like domain DUF2541 PF10807.8 CAM41715.1 - 0.11 12.6 0.0 0.38 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2541) NPL PF17800.1 CAM41716.1 - 3.1e-16 59.8 0.1 3.1e-16 59.8 0.1 2.5 2 1 0 2 2 2 1 Nucleoplasmin-like domain NPL PF17800.1 CAM41717.1 - 1.1e-11 45.3 0.0 1.1e-11 45.3 0.0 2.3 2 1 0 2 2 2 1 Nucleoplasmin-like domain CDC27 PF09507.10 CAM41717.1 - 0.028 13.8 24.7 0.04 13.3 24.7 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 FeS_assembly_P PF01883.19 CAM41718.1 - 1.9e-09 37.6 0.0 5.2e-09 36.2 0.0 1.7 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein Glyco_hydro_1 PF00232.18 CAM41718.1 - 0.035 12.5 0.0 0.035 12.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 PIF1 PF05970.14 CAM41719.1 - 1.9e-42 145.8 0.0 8.6e-34 117.3 0.0 2.8 3 0 0 3 3 3 2 PIF1-like helicase AAA_30 PF13604.6 CAM41719.1 - 3.8e-15 56.1 0.0 6.7e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 CAM41719.1 - 4e-10 38.3 3.1 2.9e-06 25.5 0.1 2.1 2 0 0 2 2 2 2 Helicase AAA_19 PF13245.6 CAM41719.1 - 6.2e-10 39.6 0.0 1.4e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CAM41719.1 - 1.5e-05 24.9 0.0 0.00019 21.3 0.0 2.7 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 CAM41719.1 - 0.00028 20.8 0.2 0.18 11.6 0.0 3.2 2 1 0 3 3 3 1 AAA domain AAA_22 PF13401.6 CAM41719.1 - 0.00036 20.8 0.0 0.0009 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CAM41719.1 - 0.0035 17.3 0.0 0.0097 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) T2SSE PF00437.20 CAM41719.1 - 0.0038 16.3 0.1 0.0076 15.3 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_7 PF12775.7 CAM41719.1 - 0.013 15.0 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 CAM41719.1 - 0.015 15.7 0.2 0.04 14.3 0.2 1.7 1 0 0 1 1 1 0 AAA ATPase domain UvrD_C_2 PF13538.6 CAM41719.1 - 0.036 13.9 0.1 0.13 12.2 0.1 2.0 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain Mg_chelatase PF01078.21 CAM41719.1 - 0.055 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 CAM41719.1 - 0.085 13.4 0.1 0.18 12.3 0.1 1.4 1 0 0 1 1 1 0 ABC transporter SH3_13 PF18335.1 CAM41719.1 - 0.097 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain NACHT PF05729.12 CAM41719.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Rotamase PF00639.21 CAM41720.1 - 2.4e-20 73.3 0.0 2.6e-20 73.2 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 CAM41720.1 - 1.1e-15 58.2 0.0 1.3e-15 57.9 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 CAM41720.1 - 0.021 15.6 0.0 0.027 15.3 0.0 1.1 1 0 0 1 1 1 0 PPIC-type PPIASE domain E1-E2_ATPase PF00122.20 CAM41723.1 - 1.2e-22 80.3 0.0 5.1e-22 78.3 0.0 2.1 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CAM41723.1 - 7.4e-12 46.0 2.4 7.7e-05 23.1 0.7 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CAM41723.1 - 0.0016 18.5 0.0 0.004 17.2 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CAM41723.1 - 0.02 14.6 0.3 0.059 13.1 0.1 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Glyco_hydr_116N PF12215.8 CAM41723.1 - 0.18 11.2 0.2 0.33 10.4 0.2 1.3 1 0 0 1 1 1 0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term Cation_ATPase_C PF00689.21 CAM41723.1 - 1.6 8.4 18.6 0.053 13.2 9.5 2.8 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus Dpy-30 PF05186.13 CAM41724.2 - 9.7e-12 44.4 0.0 1.6e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Dpy-30 motif HPP PF04982.13 CAM41724.2 - 0.054 13.7 0.2 0.068 13.4 0.2 1.1 1 0 0 1 1 1 0 HPP family BPL_LplA_LipB PF03099.19 CAM41725.1 - 1.1e-07 31.8 0.0 3.4e-07 30.2 0.0 1.8 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family zf-C2H2 PF00096.26 CAM41726.2 - 1.4e-07 31.6 8.1 0.00029 21.1 1.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CAM41726.2 - 7.3e-07 29.5 8.0 0.0068 17.1 0.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 CAM41726.2 - 0.00021 22.0 0.0 0.4 11.4 0.0 2.3 2 0 0 2 2 2 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 CAM41726.2 - 0.00064 19.6 6.6 0.059 13.4 0.6 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger DUF629 PF04780.12 CAM41726.2 - 0.0015 17.1 0.6 0.79 8.2 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF629) zf-Di19 PF05605.12 CAM41726.2 - 0.0053 17.0 1.8 0.37 11.1 0.4 2.6 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding PHD_Oberon PF07227.11 CAM41726.2 - 0.013 15.4 0.7 0.48 10.3 0.2 2.3 2 0 0 2 2 2 0 PHD - plant homeodomain finger protein zf-C2H2_2 PF12756.7 CAM41726.2 - 0.014 15.7 3.5 0.51 10.7 0.4 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf_C2H2_ZHX PF18387.1 CAM41726.2 - 0.017 14.7 1.6 4.7 6.9 0.1 2.3 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-trcl PF13451.6 CAM41726.2 - 0.033 14.1 1.7 1.1 9.3 0.1 2.3 2 0 0 2 2 2 0 Probable zinc-ribbon domain zf-met PF12874.7 CAM41726.2 - 0.059 13.8 4.3 0.1 13.1 1.1 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 CAM41726.2 - 0.066 13.3 1.2 1.3 9.2 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf_UBZ PF18439.1 CAM41726.2 - 0.067 12.8 0.9 4.5 6.9 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-H2C2_2 PF13465.6 CAM41726.2 - 0.068 13.6 3.3 8.1 7.1 0.2 3.0 2 0 0 2 2 2 0 Zinc-finger double domain CpXC PF14353.6 CAM41726.2 - 0.11 12.6 1.4 8.8 6.4 0.1 2.2 2 0 0 2 2 2 0 CpXC protein Actin_micro PF17003.5 CAM41726.2 - 0.16 11.2 0.1 3.7 6.6 0.0 2.0 2 0 0 2 2 2 0 Putative actin-like family TFIIS_C PF01096.18 CAM41726.2 - 0.16 11.8 4.3 2.6 8.0 0.3 2.6 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-C2H2_jaz PF12171.8 CAM41726.2 - 0.3 11.4 3.8 0.77 10.1 0.7 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding OrsD PF12013.8 CAM41726.2 - 0.33 11.4 2.1 1.6 9.2 0.1 2.2 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-LYAR PF08790.11 CAM41726.2 - 0.62 10.0 3.1 15 5.6 0.4 2.9 3 0 0 3 3 2 0 LYAR-type C2HC zinc finger zf-met2 PF12907.7 CAM41726.2 - 0.74 10.0 7.0 0.081 13.1 1.6 2.2 2 0 0 2 2 2 0 Zinc-binding HPS3_N PF14761.6 CAM41727.1 - 0.0037 16.8 0.4 0.49 9.9 0.0 3.0 2 1 1 3 3 3 1 Hermansky-Pudlak syndrome 3 Coatomer_WDAD PF04053.14 CAM41727.1 - 0.012 14.7 0.1 0.024 13.7 0.1 1.4 1 0 0 1 1 1 0 Coatomer WD associated region DivIC PF04977.15 CAM41727.1 - 0.28 11.0 7.2 0.13 12.0 2.2 2.9 1 1 1 2 2 2 0 Septum formation initiator BLOC1_2 PF10046.9 CAM41727.1 - 0.52 10.6 11.7 0.056 13.7 4.4 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FAM76 PF16046.5 CAM41727.1 - 3.1 7.1 14.5 5.7 6.2 14.5 1.4 1 0 0 1 1 1 0 FAM76 protein FAM167 PF11652.8 CAM41727.1 - 3.9 8.0 6.3 20 5.8 6.3 2.3 1 1 0 1 1 1 0 FAM167 FA_desaturase PF00487.24 CAM41728.1 - 1.6e-38 133.0 24.1 1.6e-38 133.0 24.1 1.4 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 CAM41728.1 - 0.016 15.3 0.0 0.034 14.3 0.0 1.5 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain Dus PF01207.17 CAM41729.1 - 0.037 13.1 0.2 0.054 12.6 0.2 1.2 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) VWA_2 PF13519.6 CAM41732.1 - 8.8e-13 48.8 0.2 1.1e-11 45.3 0.0 2.4 1 1 1 2 2 2 1 von Willebrand factor type A domain UIM PF02809.20 CAM41732.1 - 0.00012 21.7 4.8 0.00012 21.7 4.8 3.5 3 0 0 3 3 3 2 Ubiquitin interaction motif VWA PF00092.28 CAM41732.1 - 0.012 15.8 0.1 0.02 15.1 0.1 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain Ssl1 PF04056.14 CAM41732.1 - 0.039 13.8 0.0 0.056 13.3 0.0 1.2 1 0 0 1 1 1 0 Ssl1-like EF-hand_1 PF00036.32 CAM41733.1 - 0.14 11.7 0.2 0.67 9.6 0.0 2.2 2 0 0 2 2 2 0 EF hand PMSR PF01625.21 CAM41734.1 - 4.9e-52 176.2 0.3 6e-52 175.9 0.3 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Chorein_N PF12624.7 CAM41735.1 - 1.2e-06 28.6 0.0 9.3e-06 25.8 0.0 2.5 3 0 0 3 3 3 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 CAM41735.1 - 0.0018 18.1 0.0 0.0051 16.6 0.0 1.7 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal Aa_trans PF01490.18 CAM41736.1 - 1.3e-58 198.6 21.8 1.5e-58 198.4 21.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CAM41736.1 - 8.9e-10 38.1 8.2 8.9e-10 38.1 8.2 2.1 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Pkinase PF00069.25 CAM41738.2 - 5e-51 173.6 0.0 8.5e-51 172.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM41738.2 - 3.4e-35 121.6 0.0 9.4e-34 116.9 0.0 2.8 1 1 0 1 1 1 1 Protein tyrosine kinase PX PF00787.24 CAM41738.2 - 0.00079 19.4 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 PX domain Kinase-like PF14531.6 CAM41738.2 - 0.052 12.9 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 CAM41738.2 - 0.18 10.5 0.0 0.33 9.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase LpqV PF17301.2 CAM41738.2 - 0.81 9.9 5.0 40 4.5 0.0 3.7 3 0 0 3 3 3 0 Putative lipoprotein LpqV Glyco_transf_10 PF00852.19 CAM41739.1 - 1.2e-15 57.7 0.0 1.7e-08 34.4 0.0 3.3 3 0 0 3 3 3 3 Glycosyltransferase family 10 (fucosyltransferase) C-term DHR10 PF18595.1 CAM41740.1 - 0.0038 17.3 3.3 0.0038 17.3 3.3 1.9 2 0 0 2 2 2 1 Designed helical repeat protein 10 domain CLZ PF16526.5 CAM41740.1 - 0.0086 16.4 2.4 0.0086 16.4 2.4 1.6 2 0 0 2 2 2 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1192 PF06698.11 CAM41740.1 - 0.02 14.9 0.6 0.02 14.9 0.6 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) EspB_PE PF18625.1 CAM41740.1 - 0.028 14.9 1.7 0.043 14.3 0.2 2.0 2 0 0 2 2 2 0 ESX-1 secreted protein B PE domain DUF4407 PF14362.6 CAM41740.1 - 0.034 13.5 3.0 0.043 13.2 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SlyX PF04102.12 CAM41740.1 - 0.041 14.5 4.7 1.2 9.8 1.0 2.4 2 0 0 2 2 2 0 SlyX SYCE1 PF15233.6 CAM41740.1 - 0.059 13.4 7.8 0.2 11.7 7.8 1.8 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 DUF3138 PF11336.8 CAM41740.1 - 0.11 11.1 0.3 0.13 10.8 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DivIC PF04977.15 CAM41740.1 - 0.16 11.8 4.9 3.1 7.7 1.4 2.3 2 0 0 2 2 2 0 Septum formation initiator CDRT4 PF15213.6 CAM41740.1 - 0.25 11.9 2.1 0.39 11.3 1.7 1.5 1 1 1 2 2 2 0 CMT1A duplicated region transcript 4 protein AAA_assoc_C PF09821.9 CAM41740.1 - 0.38 11.3 4.0 4.1 8.0 0.1 2.1 2 0 0 2 2 2 0 C-terminal AAA-associated domain DUF724 PF05266.14 CAM41740.1 - 0.44 10.3 5.5 0.44 10.3 4.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF724) FlaC_arch PF05377.11 CAM41740.1 - 0.63 10.5 4.2 1.2 9.6 3.4 1.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) ANAPC4_WD40 PF12894.7 CAM41741.1 - 0.00049 20.3 0.0 1.3 9.4 0.0 3.5 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 CAM41741.1 - 0.051 11.9 0.0 0.23 9.7 0.0 1.9 2 1 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 CAM41741.1 - 0.073 12.4 0.0 19 4.4 0.0 2.9 2 1 1 3 3 3 0 WD40-like domain DUF2415 PF10313.9 CAM41741.1 - 0.089 12.7 0.1 0.34 10.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) WD40 PF00400.32 CAM41741.1 - 2.2 9.3 7.1 1.7e+02 3.3 0.5 4.9 6 0 0 6 6 6 0 WD domain, G-beta repeat PEX11 PF05648.14 CAM41744.1 - 2.9e-09 36.7 2.2 2.7e-05 23.8 0.1 2.4 2 1 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) PIG-L PF02585.17 CAM41745.1 - 5.2e-22 78.9 0.0 7.4e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase HhH-GPD PF00730.25 CAM41746.1 - 1.2e-19 70.7 0.0 2e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 CAM41746.1 - 1.9e-07 30.6 0.0 4.8e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 CAM41746.1 - 0.013 15.8 3.4 0.023 15.0 3.4 1.4 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Toxin_R_bind_C PF07951.12 CAM41746.1 - 0.067 12.8 0.0 0.094 12.4 0.0 1.2 1 0 0 1 1 1 0 Clostridium neurotoxin, C-terminal receptor binding RRM_1 PF00076.22 CAM41747.1 - 2.6e-18 65.6 0.0 3.3e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAM41747.1 - 0.00026 21.0 0.1 0.0014 18.7 0.0 2.2 1 1 1 2 2 2 1 RNA recognition motif RNA_bind PF08675.11 CAM41747.1 - 0.014 15.4 0.0 0.034 14.2 0.0 1.7 1 0 0 1 1 1 0 RNA binding domain HA2 PF04408.23 CAM41748.1 - 2.2e-18 66.5 0.1 8.9e-18 64.6 0.1 2.1 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CAM41748.1 - 2.4e-13 50.2 0.0 5.3e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CAM41748.1 - 1.2e-11 44.9 0.0 3.3e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CAM41748.1 - 9.9e-11 41.7 0.1 2.7e-10 40.3 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase RWD PF05773.22 CAM41748.1 - 2.1e-05 24.8 0.0 7.2e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 RWD domain zf-CCHC PF00098.23 CAM41748.1 - 6.1e-05 22.9 5.4 6.8e-05 22.8 0.9 2.6 2 0 0 2 2 2 1 Zinc knuckle T2SSE PF00437.20 CAM41748.1 - 0.00014 21.0 0.0 0.00031 19.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 CAM41748.1 - 0.00023 21.5 0.2 0.00074 19.9 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CAM41748.1 - 0.0015 18.8 0.6 0.014 15.7 0.3 2.8 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CAM41748.1 - 0.0099 15.6 0.1 0.027 14.2 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 CAM41748.1 - 0.044 14.3 0.1 0.2 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain LPD22 PF18834.1 CAM41748.1 - 0.061 13.5 0.1 20 5.5 0.1 2.5 2 0 0 2 2 2 0 Large polyvalent protein associated domain 22 ATPase PF06745.13 CAM41748.1 - 0.063 12.6 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 KaiC RRM_1 PF00076.22 CAM41749.1 - 7.6e-18 64.1 0.0 1.4e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAM41749.1 - 0.0095 16.0 0.0 0.024 14.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 CAM41749.1 - 0.021 14.4 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 CAM41750.1 - 4e-16 58.6 0.0 6.4e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAM41750.1 - 0.18 12.0 0.0 0.47 10.6 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif Sporozoite_P67 PF05642.11 CAM41750.1 - 0.89 7.6 3.3 0.76 7.8 0.4 1.9 2 0 0 2 2 2 0 Sporozoite P67 surface antigen BILBO1_N PF18281.1 CAM41751.1 - 2.4e-31 108.0 0.1 8e-31 106.3 0.1 2.0 1 0 0 1 1 1 1 BILBO1 N-terminal domain EF-hand_7 PF13499.6 CAM41751.1 - 2.3e-10 40.8 3.4 2.3e-10 40.8 3.4 2.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CAM41751.1 - 1.2e-06 27.6 3.8 0.016 14.7 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CAM41751.1 - 1.9e-05 24.2 2.9 0.14 12.2 0.4 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 CAM41751.1 - 0.0012 18.7 2.0 0.022 14.6 0.9 2.5 1 1 1 2 2 2 2 EF-hand domain pair Tropomyosin_1 PF12718.7 CAM41751.1 - 0.015 15.5 4.7 0.015 15.5 4.7 3.3 2 1 1 3 3 3 0 Tropomyosin like DUF3584 PF12128.8 CAM41751.1 - 0.097 10.2 62.9 0.027 12.0 33.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) EF-hand_5 PF13202.6 CAM41751.1 - 0.099 12.2 0.0 0.31 10.6 0.0 1.9 1 0 0 1 1 1 0 EF hand MscS_porin PF12795.7 CAM41751.1 - 2.1 7.9 47.4 0.21 11.1 11.3 2.8 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain Phycobilisome PF00502.19 CAM41752.1 - 0.0041 17.1 0.6 0.0054 16.7 0.6 1.2 1 0 0 1 1 1 1 Phycobilisome protein HTH_Tnp_ISL3 PF13542.6 CAM41752.1 - 0.19 11.2 2.2 0.33 10.4 1.3 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Kinesin PF00225.23 CAM41754.1 - 4e-75 252.8 8.5 1.8e-45 155.3 0.0 3.9 4 2 0 4 4 4 2 Kinesin motor domain Microtub_bd PF16796.5 CAM41754.1 - 9.6e-16 58.1 0.0 3e-15 56.4 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding AAA_22 PF13401.6 CAM41754.1 - 0.02 15.1 0.0 0.02 15.1 0.0 3.2 3 1 0 3 3 3 0 AAA domain Fez1 PF06818.15 CAM41754.1 - 1.3 9.5 49.8 0.026 15.0 12.2 4.5 2 1 2 4 4 4 0 Fez1 DUF87 PF01935.17 CAM41754.1 - 2.4 8.2 0.0 2.4 8.2 0.0 3.4 3 1 0 3 3 3 0 Helicase HerA, central domain zf-CRD PF17979.1 CAM41755.1 - 3.2e-43 147.6 0.4 3.2e-43 147.6 0.4 2.6 2 1 0 2 2 1 1 Cysteine rich domain with multizinc binding regions FHA PF00498.26 CAM41755.1 - 2.4e-15 56.6 0.0 8.7e-15 54.8 0.0 2.0 1 0 0 1 1 1 1 FHA domain FHA_2 PF17913.1 CAM41755.1 - 2.1e-06 27.9 0.0 3.6e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-C3HC4 PF00097.25 CAM41755.1 - 2.3e-06 27.3 12.5 2.3e-06 27.3 12.5 3.4 4 1 0 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHH PF10283.9 CAM41755.1 - 7.1e-06 25.9 10.4 7.1e-06 25.9 10.4 2.0 2 0 0 2 2 2 1 PBZ domain zf-C3HC4_2 PF13923.6 CAM41755.1 - 0.0003 20.6 13.7 0.0003 20.6 13.7 4.1 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CAM41755.1 - 0.0003 20.9 13.1 0.0003 20.9 13.1 3.5 5 0 0 5 5 4 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 CAM41755.1 - 0.00039 20.7 15.3 0.00039 20.7 15.3 4.1 5 1 0 5 5 3 1 Ring finger domain zf-RING_6 PF14835.6 CAM41755.1 - 0.00048 19.9 5.6 0.00048 19.9 5.6 2.9 2 1 1 3 3 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 CAM41755.1 - 0.00056 19.9 14.3 0.00056 19.9 14.3 3.1 4 0 0 4 4 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CAM41755.1 - 0.0013 18.7 13.6 0.0013 18.7 13.6 4.0 3 1 0 3 3 2 1 zinc-RING finger domain Yop-YscD_cpl PF16697.5 CAM41755.1 - 0.0014 18.9 0.2 0.0061 16.9 0.1 2.1 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain zf-Nse PF11789.8 CAM41755.1 - 0.56 10.1 10.0 0.38 10.6 7.1 2.3 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Atg8 PF02991.16 CAM41756.1 - 1.6e-05 25.0 0.0 2.9e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Atg8 PF02991.16 CAM41757.1 - 2.7e-05 24.3 0.0 5e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like zf-Paramyx-P PF13008.7 CAM41758.1 - 0.051 13.1 0.2 0.087 12.3 0.2 1.3 1 0 0 1 1 1 0 Zinc-binding domain of Paramyxoviridae V protein DUF4586 PF15239.6 CAM41760.1 - 4.3e-34 119.1 5.9 6.7e-34 118.4 5.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) VTC PF09359.10 CAM41761.1 - 1.1e-77 261.2 0.0 1.5e-77 260.7 0.0 1.2 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 CAM41761.1 - 0.0019 18.6 0.1 0.0019 18.6 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Phtf-FEM1B_bdg PF12129.8 CAM41761.1 - 0.091 12.6 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor AAA_2 PF07724.14 CAM41762.1 - 6.5e-42 143.5 0.4 9.7e-34 116.9 0.1 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 CAM41762.1 - 9.6e-13 48.7 0.5 5.8e-05 23.5 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CAM41762.1 - 2.4e-06 27.6 0.1 8.1e-05 22.6 0.0 3.0 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.9 CAM41762.1 - 6.1e-06 26.2 0.3 2.9e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein MCM PF00493.23 CAM41762.1 - 7.9e-05 21.9 0.1 0.0082 15.3 0.0 2.4 2 0 0 2 2 2 1 MCM P-loop domain AAA_22 PF13401.6 CAM41762.1 - 9.5e-05 22.7 0.0 0.0041 17.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CAM41762.1 - 0.002 18.5 3.6 0.02 15.3 2.7 2.8 2 1 0 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.26 CAM41762.1 - 0.0091 15.7 0.1 0.16 11.7 0.0 2.8 3 0 0 3 3 2 1 Sigma-54 interaction domain ATP-synt_ab PF00006.25 CAM41762.1 - 0.0097 15.6 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Mg_chelatase PF01078.21 CAM41762.1 - 0.012 15.0 0.5 0.054 12.9 0.0 2.4 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 CAM41762.1 - 0.014 15.1 0.1 0.54 10.0 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CAM41762.1 - 0.022 15.3 0.0 0.21 12.1 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CAM41762.1 - 0.024 15.0 0.1 0.093 13.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CAM41762.1 - 0.038 13.5 0.0 0.27 10.7 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region DEAD PF00270.29 CAM41762.1 - 0.06 13.1 0.1 9.6 5.9 0.0 2.7 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_24 PF13479.6 CAM41762.1 - 0.064 13.0 0.1 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 CAM41762.1 - 0.071 12.5 0.0 0.17 11.3 0.0 1.7 1 0 0 1 1 1 0 Bacterial TniB protein ResIII PF04851.15 CAM41762.1 - 0.12 12.3 0.1 4.5 7.3 0.0 3.0 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit UCH PF00443.29 CAM41763.1 - 6.6e-37 127.4 0.0 9.6e-37 126.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CAM41763.1 - 7.8e-05 22.4 0.1 0.00049 19.8 0.0 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MCM PF00493.23 CAM41764.1 - 3.2e-89 297.9 0.0 1.7e-88 295.5 0.0 2.0 1 1 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CAM41764.1 - 2.6e-35 121.0 0.7 4.9e-35 120.1 0.7 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CAM41764.1 - 8.1e-25 87.1 1.9 1.5e-24 86.2 1.9 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain AAA_5 PF07728.14 CAM41764.1 - 4e-09 36.6 0.0 9e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM_N PF14551.6 CAM41764.1 - 6.2e-08 33.2 0.0 1.9e-07 31.6 0.0 1.9 2 0 0 2 2 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CAM41764.1 - 6.8e-08 32.2 0.1 1.2e-05 24.8 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CAM41764.1 - 0.0021 17.8 0.2 3.1 7.5 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_3 PF07726.11 CAM41764.1 - 0.0022 17.9 0.0 0.0054 16.6 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CAM41764.1 - 0.0034 17.8 0.3 0.052 13.9 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain FAD_binding_5 PF00941.21 CAM41764.1 - 0.043 13.6 0.0 0.16 11.7 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain in molybdopterin dehydrogenase NTPase_1 PF03266.15 CAM41764.1 - 0.063 13.2 0.1 13 5.6 0.0 2.6 1 1 1 2 2 2 0 NTPase Oberon_cc PF16312.5 CAM41764.1 - 0.1 12.5 0.3 0.19 11.7 0.3 1.4 1 0 0 1 1 1 0 Coiled-coil region of Oberon TIP49_C PF17856.1 CAM41764.1 - 0.16 12.1 0.2 0.47 10.6 0.2 1.8 1 0 0 1 1 1 0 TIP49 AAA-lid domain PknG_rubred PF16919.5 CAM41764.1 - 0.19 11.9 1.0 0.95 9.6 1.0 2.1 1 0 0 1 1 1 0 Protein kinase G rubredoxin domain MFS_1 PF07690.16 CAM41765.1 - 4.5e-07 29.1 15.3 5.3e-07 28.9 15.3 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Kinesin PF00225.23 CAM41767.2 - 2.6e-30 105.5 9.8 2.6e-10 39.8 0.0 4.2 3 1 1 4 4 4 3 Kinesin motor domain Pkinase PF00069.25 CAM41769.1 - 3.9e-48 164.1 0.0 2.2e-47 161.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM41769.1 - 1.7e-18 66.9 0.0 1.2e-17 64.0 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM41769.1 - 0.0015 17.9 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CAM41769.1 - 0.0078 16.2 0.1 0.0078 16.2 0.1 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CAM41769.1 - 0.061 12.3 0.0 0.095 11.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 CAM41769.1 - 0.068 12.5 0.8 0.095 12.0 0.1 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CAM41769.1 - 0.077 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase K1 PF02960.14 CAM41770.1 - 0.062 13.4 0.3 0.18 12.0 0.3 1.7 1 0 0 1 1 1 0 K1 glycoprotein CHASE PF03924.13 CAM41770.1 - 0.32 10.9 2.5 0.7 9.8 0.0 2.6 3 0 0 3 3 3 0 CHASE domain YDG PF18657.1 CAM41771.1 - 0.02 15.1 0.3 3.9 7.7 0.5 2.8 2 0 0 2 2 2 0 YDG domain DUF3040 PF11239.8 CAM41771.1 - 0.66 10.3 3.7 8.8 6.7 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) ECD PF18432.1 CAM41772.1 - 0.053 13.5 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Extracellular Cadherin domain EphA2_TM PF14575.6 CAM41772.1 - 0.14 13.1 0.3 30 5.6 0.0 2.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain zf-rbx1 PF12678.7 CAM41773.1 - 3.7e-08 33.5 1.7 3.7e-08 33.5 1.7 2.7 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CAM41773.1 - 4.1e-08 33.4 7.1 4.1e-08 33.4 7.1 3.3 3 0 0 3 3 3 1 Ring finger domain zf-RING_11 PF17123.5 CAM41773.1 - 5.7e-05 22.8 4.7 0.0003 20.5 1.1 2.7 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CAM41773.1 - 0.00015 21.5 8.5 0.00015 21.5 8.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CAM41773.1 - 0.00041 20.2 2.2 0.00041 20.2 2.2 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CAM41773.1 - 0.00062 19.8 1.3 0.0016 18.4 1.3 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 CAM41773.1 - 0.0046 16.8 6.2 0.0046 16.8 6.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CAM41773.1 - 0.0098 15.9 4.2 0.0098 15.9 4.2 2.4 2 0 0 2 2 2 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 CAM41773.1 - 0.054 13.1 4.7 0.22 11.1 4.7 2.0 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 CAM41773.1 - 0.078 12.9 9.5 0.026 14.5 5.9 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CAM41773.1 - 5.5 7.2 9.9 1.7 8.9 5.5 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FAD_binding_7 PF03441.14 CAM41774.1 - 4.5e-34 117.7 0.1 7.6e-34 117.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 CAM41774.1 - 2.6e-18 66.6 0.1 1.5e-17 64.1 0.1 2.3 3 0 0 3 3 3 1 DNA photolyase Ank_4 PF13637.6 CAM41775.1 - 5.7e-08 33.2 0.0 1.8e-07 31.6 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CAM41775.1 - 2.8e-06 27.2 0.7 0.0016 18.7 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CAM41775.1 - 0.00015 21.9 0.6 0.00036 20.8 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CAM41775.1 - 0.00019 22.0 0.0 0.0004 20.9 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CAM41775.1 - 0.0022 18.4 1.0 0.16 12.5 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat CX9C PF16860.5 CAM41776.1 - 4.7e-05 23.3 1.3 7.7e-05 22.6 1.3 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 CAM41776.1 - 0.0063 16.6 1.2 0.33 11.2 0.1 2.2 2 0 0 2 2 2 2 CHCH domain Cmc1 PF08583.10 CAM41776.1 - 0.022 14.8 1.7 0.34 11.0 1.9 2.0 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.12 CAM41776.1 - 0.04 14.2 0.9 0.45 10.8 0.9 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) UPF0242 PF06785.11 CAM41778.1 - 0.056 13.5 9.6 0.12 12.4 9.6 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF948 PF06103.11 CAM41778.1 - 0.12 12.6 5.7 3.4 8.0 5.7 2.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF755 PF05501.11 CAM41778.1 - 0.23 11.7 9.1 0.17 12.2 6.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF755) DUF4407 PF14362.6 CAM41778.1 - 2 7.7 16.8 0.48 9.7 13.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FAM76 PF16046.5 CAM41778.1 - 3.1 7.1 8.0 5.5 6.3 8.0 1.5 1 0 0 1 1 1 0 FAM76 protein LCD1 PF09798.9 CAM41778.1 - 4 5.9 5.8 5.6 5.4 5.8 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein Fib_alpha PF08702.10 CAM41778.1 - 6.4 7.0 9.2 4.4 7.5 2.8 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Atg14 PF10186.9 CAM41778.1 - 9.8 5.2 12.2 20 4.1 12.2 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Pkinase PF00069.25 CAM41780.1 - 2.5e-05 23.8 0.0 3.4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM41780.1 - 0.0096 15.2 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CAM41781.1 - 2.5e-41 141.8 0.0 3.3e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM41781.1 - 2.6e-16 59.7 0.0 3.7e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CAM41781.1 - 0.015 15.3 1.1 2.8 7.8 0.0 2.5 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 CAM41781.1 - 0.03 13.7 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-PolyVal PF18762.1 CAM41781.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins INO80_Ies4 PF08193.11 CAM41781.1 - 0.5 10.3 4.8 0.74 9.8 4.8 1.2 1 0 0 1 1 1 0 INO80 complex subunit Ies4 DSPn PF14671.6 CAM41782.1 - 7.8e-19 68.5 0.0 1.4e-12 48.3 0.0 2.3 2 0 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 CAM41782.1 - 2.5e-08 33.8 0.1 4.7e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CAM41782.1 - 0.0013 18.3 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase HTH_28 PF13518.6 CAM41782.1 - 0.089 12.9 2.5 0.26 11.4 0.5 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Plus-3 PF03126.18 CAM41783.1 - 2.6e-13 50.4 0.0 6.6e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Plus-3 domain zf-C3HC4_3 PF13920.6 CAM41783.1 - 1.5e-09 37.6 13.9 2.4e-09 36.9 13.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CAM41783.1 - 0.017 14.9 13.6 0.036 13.9 13.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CAM41783.1 - 0.6 10.5 15.8 1.1 9.7 15.8 1.4 1 0 0 1 1 1 0 Ring finger domain TPR_1 PF00515.28 CAM41784.2 - 2.1e-16 58.9 14.2 0.0032 17.2 0.0 9.1 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 CAM41784.2 - 1.9e-12 46.3 24.6 0.077 13.1 0.0 8.8 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_8 PF13181.6 CAM41784.2 - 2.8e-12 45.8 5.1 0.087 13.1 0.0 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 CAM41784.2 - 1.3e-11 45.0 15.4 0.16 12.6 0.0 7.5 5 1 2 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 CAM41784.2 - 8.8e-10 38.6 19.8 0.064 14.1 0.9 7.7 5 2 4 9 9 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 CAM41784.2 - 1e-09 38.5 13.3 0.21 11.9 0.0 6.9 5 1 3 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 CAM41784.2 - 5.2e-08 32.9 9.0 0.0036 17.4 0.4 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 CAM41784.2 - 1.9e-07 31.5 12.5 0.1 13.1 0.3 5.6 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 CAM41784.2 - 0.00026 21.1 2.4 24 5.6 0.0 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 CAM41784.2 - 0.047 13.4 11.1 15 5.4 0.1 6.1 6 2 1 7 7 7 0 TPR repeat TPR_7 PF13176.6 CAM41784.2 - 0.17 12.0 7.9 71 3.8 0.1 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CAM41784.2 - 0.22 11.6 11.9 0.37 10.9 0.0 4.4 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 CAM41784.2 - 0.43 11.3 12.2 6.8 7.5 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat Glyco_transf_8C PF08437.10 CAM41785.1 - 0.75 9.9 3.5 0.47 10.6 0.7 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 8 C-terminal Mon2_C PF16206.5 CAM41787.1 - 1.7e-08 33.2 0.1 3.7e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 C-terminal region of Mon2 protein Metallophos PF00149.28 CAM41788.2 - 1.4e-21 77.9 0.4 2.1e-21 77.4 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase IRK_C PF17655.1 CAM41789.1 - 1.1e-07 31.6 0.5 0.00021 20.9 0.1 2.3 2 0 0 2 2 2 2 Inward rectifier potassium channel C-terminal domain Macoilin PF09726.9 CAM41789.1 - 0.74 8.3 13.6 1 7.8 13.6 1.1 1 0 0 1 1 1 0 Macoilin family Plasmodium_Vir PF05795.11 CAM41789.1 - 2.4 7.5 3.7 4 6.8 3.7 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SPX PF03105.19 CAM41789.1 - 5.2 6.9 16.5 7.4 6.4 16.5 1.2 1 0 0 1 1 1 0 SPX domain Acyltransferase PF01553.21 CAM41790.1 - 0.0017 18.0 0.0 0.0043 16.7 0.0 1.7 1 0 0 1 1 1 1 Acyltransferase bZIP_1 PF00170.21 CAM41794.2 - 0.034 14.2 1.2 0.065 13.3 1.2 1.4 1 0 0 1 1 1 0 bZIP transcription factor LRR_6 PF13516.6 CAM41794.2 - 0.068 13.3 1.9 8.2 6.8 0.0 3.9 3 0 0 3 3 3 0 Leucine Rich repeat ADIP PF11559.8 CAM41794.2 - 0.64 10.1 6.8 1.1 9.3 6.8 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding LRR_4 PF12799.7 CAM41794.2 - 1 9.9 12.6 9.1 6.9 0.8 4.7 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) YgaB PF14182.6 CAM41794.2 - 1.4 9.3 4.7 3.4 8.1 4.7 1.5 1 0 0 1 1 1 0 YgaB-like protein ZapB PF06005.12 CAM41794.2 - 1.5 9.4 6.3 3.2 8.3 6.3 1.5 1 0 0 1 1 1 0 Cell division protein ZapB Nsp1_C PF05064.13 CAM41794.2 - 1.9 8.3 3.5 3.4 7.5 3.5 1.3 1 0 0 1 1 1 0 Nsp1-like C-terminal region DSPc PF00782.20 CAM41796.2 - 2.7e-08 33.7 0.0 4e-07 29.9 0.0 2.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain 2-oxoacid_dh PF00198.23 CAM41796.2 - 0.16 11.4 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) His_Phos_1 PF00300.22 CAM41797.1 - 3.6e-11 43.1 0.0 6e-08 32.6 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) PDEase_II PF02112.15 CAM41797.1 - 0.059 12.5 0.0 0.085 11.9 0.0 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II FUSC PF04632.12 CAM41798.2 - 0.96 7.9 3.7 2.2 6.7 1.0 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family PPR_1 PF12854.7 CAM41799.1 - 0.037 13.7 0.0 0.075 12.8 0.0 1.5 1 0 0 1 1 1 0 PPR repeat PPR_2 PF13041.6 CAM41799.1 - 0.044 14.0 0.0 0.22 11.8 0.0 2.2 3 0 0 3 3 3 0 PPR repeat family PPR PF01535.20 CAM41799.1 - 0.067 13.5 0.0 11 6.5 0.0 3.0 3 0 0 3 3 3 0 PPR repeat NCKAP5 PF15246.6 CAM41800.1 - 0.04 13.5 6.4 0.06 12.9 6.4 1.2 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein Menin PF05053.13 CAM41800.1 - 0.56 8.5 6.6 0.78 8.0 6.6 1.1 1 0 0 1 1 1 0 Menin Bravo_FIGEY PF13882.6 CAM41800.1 - 1.1 10.7 5.6 3.2 9.2 5.6 1.7 1 0 0 1 1 1 0 Bravo-like intracellular region GvpL_GvpF PF06386.11 CAM41800.1 - 1.9 8.4 12.8 4.2 7.2 12.8 1.5 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF PhoLip_ATPase_C PF16212.5 CAM41802.1 - 1.2e-54 185.7 19.5 1.2e-54 185.7 19.5 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CAM41802.1 - 2.6e-21 75.1 0.3 6.7e-21 73.8 0.3 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CAM41802.1 - 1.6e-08 35.1 0.3 0.0069 16.7 0.0 3.5 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CAM41802.1 - 0.0008 19.0 0.0 0.0038 16.8 0.0 2.2 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 CAM41802.1 - 0.0088 16.1 0.0 0.75 9.9 0.0 3.2 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CAM41802.1 - 0.014 15.1 0.1 0.025 14.3 0.1 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase NUDE_C PF04880.13 CAM41802.1 - 4.1 7.9 7.4 14 6.1 0.2 3.5 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region LRR_8 PF13855.6 CAM41805.1 - 3.3e-05 23.5 0.1 0.032 14.0 0.1 2.4 1 1 1 2 2 2 2 Leucine rich repeat DUF1582 PF07621.11 CAM41805.1 - 0.0005 19.9 0.7 0.0014 18.5 0.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1582) UvrD-helicase PF00580.21 CAM41806.1 - 2.5e-39 135.7 0.0 6.9e-37 127.6 0.0 2.2 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 CAM41806.1 - 2.6e-27 96.2 0.0 7e-14 52.0 0.0 2.4 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 CAM41806.1 - 5.6e-25 88.4 0.0 1.8e-24 86.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CAM41806.1 - 1.9e-09 37.5 1.8 7.5e-06 25.8 0.6 2.5 2 0 0 2 2 2 2 AAA domain UvrD_C_2 PF13538.6 CAM41806.1 - 7.5e-09 35.3 0.0 2.4e-08 33.7 0.0 2.0 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain ResIII PF04851.15 CAM41806.1 - 0.051 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Peptidase_S51 PF03575.17 CAM41807.1 - 5.3e-24 85.0 0.0 3.5e-22 79.1 0.0 2.1 1 1 0 1 1 1 1 Peptidase family S51 AbiEi_4 PF13338.6 CAM41809.1 - 0.12 12.5 0.0 0.53 10.5 0.0 2.1 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin PH PF00169.29 CAM41810.1 - 1.5e-12 48.0 0.0 2.6e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 CAM41810.1 - 0.00026 20.8 0.1 0.032 14.0 0.1 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 CAM41810.1 - 0.02 14.9 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 PH domain DHHC PF01529.20 CAM41811.1 - 7.5e-25 87.6 15.5 7.5e-25 87.6 15.5 2.8 2 1 0 2 2 2 1 DHHC palmitoyltransferase AAA_33 PF13671.6 CAM41812.1 - 3.5e-07 30.5 0.1 1.1e-06 28.8 0.1 1.9 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CAM41812.1 - 1.2e-05 24.6 0.0 2.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 CAM41812.1 - 1.7e-05 25.4 0.0 5.2e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.20 CAM41812.1 - 0.0001 22.2 0.1 0.00089 19.2 0.0 2.1 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_16 PF13191.6 CAM41812.1 - 0.0016 18.8 0.1 0.0062 16.9 0.1 2.0 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 CAM41812.1 - 0.0035 17.3 0.1 0.0081 16.1 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_28 PF13521.6 CAM41812.1 - 0.0042 17.3 0.0 0.014 15.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 CAM41812.1 - 0.018 15.5 0.0 0.039 14.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 CAM41812.1 - 0.04 14.2 0.0 0.13 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 CAM41812.1 - 0.06 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase CPT PF07931.12 CAM41812.1 - 0.06 13.2 0.0 0.12 12.2 0.0 1.5 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein PRK PF00485.18 CAM41812.1 - 0.097 12.4 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family dNK PF01712.19 CAM41812.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_29 PF13555.6 CAM41812.1 - 0.13 12.0 0.1 1.3 8.8 0.0 2.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain UL41A PF17591.2 CAM41812.1 - 0.15 12.2 0.1 0.35 11.0 0.1 1.6 1 0 0 1 1 1 0 Herpesvirus UL41A RNA_helicase PF00910.22 CAM41812.1 - 0.16 12.4 0.0 0.45 10.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 CAM41812.1 - 0.18 12.2 0.0 0.52 10.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain DUF2075 PF09848.9 CAM41812.1 - 0.2 10.9 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TYW3 PF02676.14 CAM41813.1 - 5.6e-57 192.5 0.0 8.3e-57 192.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase TYW3 Prefoldin_2 PF01920.20 CAM41814.1 - 2.7e-18 65.9 2.0 3.6e-18 65.5 2.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit SlyX PF04102.12 CAM41814.1 - 0.11 13.1 3.8 0.42 11.3 0.1 2.4 2 0 0 2 2 2 0 SlyX GreA_GreB_N PF03449.15 CAM41814.1 - 0.16 12.2 0.5 0.16 12.2 0.5 1.8 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal CmcI PF04989.12 CAM41814.1 - 0.17 11.6 0.5 0.25 11.0 0.5 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase FapA PF03961.13 CAM41814.1 - 0.18 10.4 1.4 0.81 8.2 0.3 1.9 2 0 0 2 2 2 0 Flagellar Assembly Protein A DASH_Dad3 PF08656.10 CAM41814.1 - 0.19 11.8 4.6 0.1 12.7 1.2 1.9 2 0 0 2 2 2 0 DASH complex subunit Dad3 APG6_N PF17675.1 CAM41814.1 - 0.23 12.0 5.1 2.5 8.7 0.6 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region Spc24 PF08286.11 CAM41814.1 - 1.4 9.2 4.5 8.5 6.7 0.4 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 RNA12 PF10443.9 CAM41818.1 - 0.029 13.1 0.1 0.087 11.5 0.0 1.7 2 0 0 2 2 2 0 RNA12 protein zf_CCCH_4 PF18345.1 CAM41819.1 - 3.1e-18 65.2 28.9 5.8e-07 29.4 1.6 6.0 5 1 0 5 5 5 5 Zinc finger domain zf-CCCH PF00642.24 CAM41819.1 - 1.3e-17 63.2 30.3 0.00058 19.7 0.6 5.5 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CAM41819.1 - 2.1e-11 43.3 26.7 4.7e-07 29.4 0.6 5.0 5 0 0 5 5 5 4 CCCH-type zinc finger Torus PF16131.5 CAM41819.1 - 2.5e-11 44.2 21.0 0.00075 20.2 0.4 5.2 1 1 4 5 5 5 5 Torus domain zf-CCCH_3 PF15663.5 CAM41819.1 - 2.2e-07 31.1 7.0 2.2e-07 31.1 7.0 2.6 1 1 1 2 2 2 1 Zinc-finger containing family zf-CCHC PF00098.23 CAM41819.1 - 0.00013 21.8 11.4 0.00037 20.4 0.5 3.3 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_2 PF13696.6 CAM41819.1 - 0.00021 21.0 4.4 0.0017 18.1 0.4 3.0 2 0 0 2 2 2 1 Zinc knuckle zf-CCCH_2 PF14608.6 CAM41819.1 - 0.00051 20.4 1.1 0.00051 20.4 1.1 6.6 7 0 0 7 7 7 3 RNA-binding, Nab2-type zinc finger zf-C3H1 PF10650.9 CAM41819.1 - 3.3 7.5 8.9 0.87 9.4 0.1 3.9 3 0 0 3 3 3 0 Putative zinc-finger domain zf-UBR PF02207.20 CAM41821.1 - 5e-15 55.4 16.5 5e-15 55.4 16.5 2.8 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ACBP PF00887.19 CAM41822.1 - 2.2e-23 82.3 1.3 4.3e-23 81.3 1.3 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein Mis12 PF05859.12 CAM41822.1 - 0.14 12.2 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 Mis12 protein DUF4486 PF14858.6 CAM41823.2 - 0.046 12.2 0.1 0.1 11.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4486) HA PF03457.14 CAM41823.2 - 0.16 12.3 0.1 1.3 9.4 0.1 2.6 2 0 0 2 2 2 0 Helicase associated domain Peptidase_S9_N PF02897.15 CAM41824.1 - 5.3e-112 374.7 0.0 7e-112 374.2 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 CAM41824.1 - 3.5e-65 219.4 0.0 5.5e-65 218.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 CAM41824.1 - 0.045 13.4 0.0 0.28 10.8 0.0 2.0 1 1 0 1 1 1 0 Putative esterase DUF4464 PF14713.6 CAM41825.1 - 1.1e-85 286.7 0.1 1.3e-85 286.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) GAS PF13851.6 CAM41826.2 - 0.064 12.6 1.0 0.11 11.9 1.0 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Axin_b-cat_bind PF08833.10 CAM41826.2 - 0.95 9.6 5.9 1.2 9.3 0.1 3.9 4 0 0 4 4 4 0 Axin beta-catenin binding domain DHHC PF01529.20 CAM41826.2 - 4.9 7.3 11.9 2.2 8.4 0.9 3.6 3 0 0 3 3 3 0 DHHC palmitoyltransferase Prefoldin PF02996.17 CAM41828.1 - 3.6e-10 39.8 0.1 2e-09 37.4 0.0 2.0 2 0 0 2 2 2 1 Prefoldin subunit AAA PF00004.29 CAM41829.1 - 0.0027 18.1 0.0 0.007 16.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 CAM41829.1 - 0.012 14.9 0.0 0.042 13.1 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin Torsin PF06309.11 CAM41829.1 - 0.13 12.3 0.0 3.2 7.9 0.0 2.3 2 0 0 2 2 2 0 Torsin AAA_16 PF13191.6 CAM41829.1 - 0.14 12.5 4.5 0.31 11.4 0.2 3.5 3 1 1 4 4 4 0 AAA ATPase domain DEAD PF00270.29 CAM41830.1 - 1e-26 93.8 0.1 1.6e-26 93.1 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAM41830.1 - 1.2e-20 73.9 0.0 5.4e-20 71.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAM41830.1 - 8e-05 22.7 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CAM41830.1 - 0.019 15.3 0.2 0.06 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain SecA_DEAD PF07517.14 CAM41830.1 - 0.14 11.4 0.0 0.35 10.1 0.0 1.6 1 1 0 1 1 1 0 SecA DEAD-like domain UPF0160 PF03690.13 CAM41831.1 - 3.1e-122 408.2 0.0 3.6e-122 408.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Ras PF00071.22 CAM41832.1 - 1.5e-36 125.4 0.1 1.3e-11 44.3 0.1 3.1 3 0 0 3 3 3 3 Ras family Roc PF08477.13 CAM41832.1 - 3.6e-20 72.4 0.6 4.4e-09 36.6 0.0 3.0 2 1 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAM41832.1 - 8.1e-05 22.1 0.0 0.62 9.5 0.0 2.9 3 0 0 3 3 3 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CAM41832.1 - 0.093 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase PET117 PF15786.5 CAM41833.1 - 8.3e-06 26.0 0.0 9.6e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial EF-hand_7 PF13499.6 CAM41834.1 - 1.1e-06 28.9 0.4 2.5e-05 24.6 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CAM41834.1 - 4.1e-06 26.3 1.4 1.9e-05 24.2 0.0 2.8 4 0 0 4 4 4 1 EF-hand domain EF-hand_8 PF13833.6 CAM41834.1 - 7e-06 25.8 1.6 0.0054 16.6 0.6 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CAM41834.1 - 1.2e-05 24.5 3.5 8.9e-05 21.8 0.0 3.0 3 0 0 3 3 3 1 EF hand DUF1456 PF07308.13 CAM41834.1 - 0.026 14.9 0.6 0.76 10.2 0.0 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1456) YokU PF14122.6 CAM41834.1 - 2.1 8.4 5.5 1.9 8.5 0.7 2.6 1 1 2 3 3 3 0 YokU-like protein, putative antitoxin EF-hand_5 PF13202.6 CAM41834.1 - 5.5 6.7 0.0 5.5 6.7 0.0 3.4 4 0 0 4 4 4 0 EF hand EF-hand_1 PF00036.32 CAM41835.1 - 3e-43 142.2 12.0 1.5e-10 39.9 1.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CAM41835.1 - 1.6e-36 124.6 3.7 6.9e-19 68.1 1.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CAM41835.1 - 5e-32 109.5 11.3 1.3e-14 53.7 0.7 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 CAM41835.1 - 2.1e-31 105.1 6.6 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CAM41835.1 - 3.2e-28 95.9 9.4 5.8e-07 28.7 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 CAM41835.1 - 6.6e-16 58.4 0.2 6.8e-09 35.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CAM41835.1 - 1.3e-09 37.9 0.8 5.4e-05 23.1 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CAM41835.1 - 6.6e-08 32.9 0.0 0.0014 18.9 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 CAM41835.1 - 2.6e-06 28.2 0.0 0.00063 20.6 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 CAM41835.1 - 1.9e-05 24.6 1.0 0.035 14.1 0.0 3.3 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 CAM41835.1 - 0.00016 21.7 1.1 0.00074 19.6 0.1 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 CAM41835.1 - 0.00017 21.7 2.8 0.017 15.3 0.4 3.1 1 1 2 3 3 3 1 Dockerin type I domain TerB PF05099.13 CAM41835.1 - 0.00041 20.3 0.3 0.23 11.4 0.0 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB DUF3349 PF11829.8 CAM41835.1 - 0.00091 20.0 0.3 3.2 8.6 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Caleosin PF05042.13 CAM41835.1 - 0.0013 18.6 0.8 0.21 11.5 0.3 3.3 1 1 1 2 2 2 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 CAM41835.1 - 0.0018 18.6 0.3 1.6 9.1 0.1 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb4 DUF4497 PF14924.6 CAM41835.1 - 0.0024 18.3 0.0 0.92 10.0 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4497) Poly_export PF02563.16 CAM41835.1 - 0.0042 17.3 0.2 0.9 9.8 0.0 3.1 1 1 0 2 2 2 1 Polysaccharide biosynthesis/export protein MotA_activ PF09114.10 CAM41835.1 - 0.0059 16.7 0.0 0.12 12.5 0.0 2.2 2 0 0 2 2 2 1 Transcription factor MotA, activation domain DUF1103 PF06513.11 CAM41835.1 - 0.0061 16.2 1.1 0.0071 16.0 1.1 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) SurA_N_2 PF13623.6 CAM41835.1 - 0.015 15.2 1.4 0.56 10.1 0.2 2.2 1 1 1 2 2 2 0 SurA N-terminal domain DUF5580 PF17743.1 CAM41835.1 - 0.019 13.6 0.0 0.019 13.5 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_14 PF17959.1 CAM41835.1 - 0.033 14.5 0.2 5.6 7.4 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain dCache_2 PF08269.11 CAM41835.1 - 0.04 13.1 0.1 2.7 7.1 0.0 2.2 1 1 0 2 2 2 0 Cache domain Fe_hyd_lg_C PF02906.14 CAM41835.1 - 0.045 13.4 0.2 0.11 12.1 0.2 1.7 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain RloB PF13707.6 CAM41835.1 - 0.081 13.1 0.9 1.1 9.4 0.1 2.1 1 1 1 2 2 2 0 RloB-like protein EF-hand_1 PF00036.32 CAM41836.1 - 3e-43 142.2 12.0 1.5e-10 39.9 1.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CAM41836.1 - 1.6e-36 124.6 3.7 6.9e-19 68.1 1.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CAM41836.1 - 5e-32 109.5 11.3 1.3e-14 53.7 0.7 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 CAM41836.1 - 2.1e-31 105.1 6.6 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CAM41836.1 - 3.2e-28 95.9 9.4 5.8e-07 28.7 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 CAM41836.1 - 6.6e-16 58.4 0.2 6.8e-09 35.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CAM41836.1 - 1.3e-09 37.9 0.8 5.4e-05 23.1 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CAM41836.1 - 6.6e-08 32.9 0.0 0.0014 18.9 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 CAM41836.1 - 2.6e-06 28.2 0.0 0.00063 20.6 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 CAM41836.1 - 1.9e-05 24.6 1.0 0.035 14.1 0.0 3.3 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 CAM41836.1 - 0.00016 21.7 1.1 0.00074 19.6 0.1 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 CAM41836.1 - 0.00017 21.7 2.8 0.017 15.3 0.4 3.1 1 1 2 3 3 3 1 Dockerin type I domain TerB PF05099.13 CAM41836.1 - 0.00041 20.3 0.3 0.23 11.4 0.0 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB DUF3349 PF11829.8 CAM41836.1 - 0.00091 20.0 0.3 3.2 8.6 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Caleosin PF05042.13 CAM41836.1 - 0.0013 18.6 0.8 0.21 11.5 0.3 3.3 1 1 1 2 2 2 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 CAM41836.1 - 0.0018 18.6 0.3 1.6 9.1 0.1 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb4 DUF4497 PF14924.6 CAM41836.1 - 0.0024 18.3 0.0 0.92 10.0 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4497) Poly_export PF02563.16 CAM41836.1 - 0.0042 17.3 0.2 0.9 9.8 0.0 3.1 1 1 0 2 2 2 1 Polysaccharide biosynthesis/export protein MotA_activ PF09114.10 CAM41836.1 - 0.0059 16.7 0.0 0.12 12.5 0.0 2.2 2 0 0 2 2 2 1 Transcription factor MotA, activation domain DUF1103 PF06513.11 CAM41836.1 - 0.0061 16.2 1.1 0.0071 16.0 1.1 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) SurA_N_2 PF13623.6 CAM41836.1 - 0.015 15.2 1.4 0.56 10.1 0.2 2.2 1 1 1 2 2 2 0 SurA N-terminal domain DUF5580 PF17743.1 CAM41836.1 - 0.019 13.6 0.0 0.019 13.5 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_14 PF17959.1 CAM41836.1 - 0.033 14.5 0.2 5.6 7.4 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain dCache_2 PF08269.11 CAM41836.1 - 0.04 13.1 0.1 2.7 7.1 0.0 2.2 1 1 0 2 2 2 0 Cache domain Fe_hyd_lg_C PF02906.14 CAM41836.1 - 0.045 13.4 0.2 0.11 12.1 0.2 1.7 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain RloB PF13707.6 CAM41836.1 - 0.081 13.1 0.9 1.1 9.4 0.1 2.1 1 1 1 2 2 2 0 RloB-like protein EF-hand_1 PF00036.32 CAM41837.1 - 3e-43 142.2 12.0 1.5e-10 39.9 1.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CAM41837.1 - 1.6e-36 124.6 3.7 6.9e-19 68.1 1.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CAM41837.1 - 5e-32 109.5 11.3 1.3e-14 53.7 0.7 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 CAM41837.1 - 2.1e-31 105.1 6.6 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CAM41837.1 - 3.2e-28 95.9 9.4 5.8e-07 28.7 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 CAM41837.1 - 6.6e-16 58.4 0.2 6.8e-09 35.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CAM41837.1 - 1.3e-09 37.9 0.8 5.4e-05 23.1 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CAM41837.1 - 6.6e-08 32.9 0.0 0.0014 18.9 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 CAM41837.1 - 2.6e-06 28.2 0.0 0.00063 20.6 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 CAM41837.1 - 1.9e-05 24.6 1.0 0.035 14.1 0.0 3.3 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 CAM41837.1 - 0.00016 21.7 1.1 0.00074 19.6 0.1 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 CAM41837.1 - 0.00017 21.7 2.8 0.017 15.3 0.4 3.1 1 1 2 3 3 3 1 Dockerin type I domain TerB PF05099.13 CAM41837.1 - 0.00041 20.3 0.3 0.23 11.4 0.0 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB DUF3349 PF11829.8 CAM41837.1 - 0.00091 20.0 0.3 3.2 8.6 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Caleosin PF05042.13 CAM41837.1 - 0.0013 18.6 0.8 0.21 11.5 0.3 3.3 1 1 1 2 2 2 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 CAM41837.1 - 0.0018 18.6 0.3 1.6 9.1 0.1 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb4 DUF4497 PF14924.6 CAM41837.1 - 0.0024 18.3 0.0 0.92 10.0 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4497) Poly_export PF02563.16 CAM41837.1 - 0.0042 17.3 0.2 0.9 9.8 0.0 3.1 1 1 0 2 2 2 1 Polysaccharide biosynthesis/export protein MotA_activ PF09114.10 CAM41837.1 - 0.0059 16.7 0.0 0.12 12.5 0.0 2.2 2 0 0 2 2 2 1 Transcription factor MotA, activation domain DUF1103 PF06513.11 CAM41837.1 - 0.0061 16.2 1.1 0.0071 16.0 1.1 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) SurA_N_2 PF13623.6 CAM41837.1 - 0.015 15.2 1.4 0.56 10.1 0.2 2.2 1 1 1 2 2 2 0 SurA N-terminal domain DUF5580 PF17743.1 CAM41837.1 - 0.019 13.6 0.0 0.019 13.5 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_14 PF17959.1 CAM41837.1 - 0.033 14.5 0.2 5.6 7.4 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain dCache_2 PF08269.11 CAM41837.1 - 0.04 13.1 0.1 2.7 7.1 0.0 2.2 1 1 0 2 2 2 0 Cache domain Fe_hyd_lg_C PF02906.14 CAM41837.1 - 0.045 13.4 0.2 0.11 12.1 0.2 1.7 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain RloB PF13707.6 CAM41837.1 - 0.081 13.1 0.9 1.1 9.4 0.1 2.1 1 1 1 2 2 2 0 RloB-like protein FbpA PF05833.11 CAM41838.1 - 1.9e-27 96.2 8.6 3.6e-21 75.5 0.0 2.7 3 0 0 3 3 3 2 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 CAM41838.1 - 1e-22 80.8 0.0 2.9e-22 79.4 0.0 1.8 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-C PF11923.8 CAM41838.1 - 1.1e-07 31.7 0.0 6.9e-07 29.1 0.0 2.4 1 0 0 1 1 1 1 NFACT protein C-terminal domain Anophelin PF10731.9 CAM41838.1 - 0.14 12.0 0.5 0.36 10.7 0.5 1.6 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito SepSecS PF05889.13 CAM41839.1 - 6.3e-91 305.0 0.0 3.1e-50 171.0 0.0 3.5 3 1 0 3 3 3 3 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 CAM41839.1 - 0.00025 20.4 0.0 0.00038 19.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase EF1G PF00647.19 CAM41841.1 - 6.5e-40 135.5 0.2 2e-39 133.9 0.2 1.9 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 CAM41841.1 - 1.3e-12 47.9 0.1 4.6e-12 46.1 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CAM41841.1 - 6.7e-12 45.5 0.0 6.7e-12 45.5 0.0 2.3 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CAM41841.1 - 2.1e-06 27.8 1.3 5.6e-06 26.5 0.0 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CAM41841.1 - 4.5e-05 23.4 0.0 0.00012 22.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CAM41841.1 - 0.00061 20.1 0.0 0.0018 18.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PAM2 PF07145.15 CAM41842.1 - 0.00026 20.5 3.7 0.012 15.2 0.0 3.3 3 0 0 3 3 3 2 Ataxin-2 C-terminal region Chorein_N PF12624.7 CAM41843.1 - 2e-22 79.5 0.0 6.3e-22 77.9 0.0 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 CAM41843.1 - 1e-14 55.0 0.0 2.1e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal PUB PF09409.10 CAM41844.2 - 6.8e-12 45.2 0.0 1.5e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 PUB domain zf-CHCC PF10276.9 CAM41844.2 - 0.0017 18.4 0.4 0.005 16.9 0.4 1.8 1 0 0 1 1 1 1 Zinc-finger domain OB_RNB PF08206.11 CAM41844.2 - 0.047 13.4 0.1 0.093 12.4 0.1 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain DUF2256 PF10013.9 CAM41844.2 - 0.12 12.6 1.7 0.25 11.5 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Big_3_3 PF13750.6 CAM41845.1 - 0.098 12.3 0.0 0.94 9.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) CDC50 PF03381.15 CAM41847.1 - 2.5e-64 217.5 0.0 4.8e-64 216.6 0.0 1.4 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family RNF111_N PF15303.6 CAM41847.1 - 0.0055 16.5 8.2 0.0086 15.9 8.2 1.2 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase Arkadia N-terminus CCDC14 PF15254.6 CAM41847.1 - 0.36 9.4 0.6 0.53 8.9 0.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 PTS_EIIB PF00367.20 CAM41848.1 - 0.069 12.7 0.2 0.16 11.5 0.2 1.5 1 0 0 1 1 1 0 phosphotransferase system, EIIB APG6_N PF17675.1 CAM41848.1 - 0.54 10.8 7.0 0.31 11.6 2.4 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region UPF0242 PF06785.11 CAM41848.1 - 1.6 8.8 5.3 2.6 8.1 0.7 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CENP-F_leu_zip PF10473.9 CAM41848.1 - 7.7 6.5 9.0 1.2 9.2 1.4 2.7 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PRKG1_interact PF15898.5 CAM41848.1 - 8.7 7.3 13.3 0.77 10.7 4.9 2.4 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain LCAT PF02450.15 CAM41849.1 - 1.2e-45 156.4 0.0 3.9e-35 121.8 0.0 2.2 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 CAM41849.1 - 0.0053 17.4 0.3 0.0053 17.4 0.3 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Rrp44_CSD1 PF17216.3 CAM41849.1 - 0.0071 16.1 0.0 0.021 14.5 0.0 1.7 2 0 0 2 2 2 1 Rrp44-like cold shock domain Hairy_orange PF07527.13 CAM41849.1 - 0.025 14.8 0.0 0.056 13.7 0.0 1.6 1 0 0 1 1 1 0 Hairy Orange Motile_Sperm PF00635.26 CAM41850.1 - 3.3e-11 43.0 0.0 5.8e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain SHS2_Rpb7-N PF03876.17 CAM41851.1 - 1e-24 86.7 0.0 2e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.12 CAM41851.1 - 5.5e-09 36.3 0.0 1.2e-07 32.1 0.0 2.5 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 eIF2_C PF09173.11 CAM41852.1 - 1.6e-26 92.4 0.1 4.2e-26 91.0 0.1 1.8 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 CAM41852.1 - 3.9e-23 82.0 0.1 1e-22 80.6 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CAM41852.1 - 4.2e-06 27.1 1.5 2.3e-05 24.7 0.8 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CAM41852.1 - 6.8e-05 22.9 0.0 0.00073 19.6 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CAM41852.1 - 0.00081 19.3 0.7 0.027 14.4 0.1 2.5 3 0 0 3 3 3 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 CAM41852.1 - 0.039 14.0 0.3 0.44 10.6 0.1 2.6 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 CAM41852.1 - 0.06 13.4 0.0 0.86 9.6 0.0 2.4 2 0 0 2 2 2 0 Dynamin family IBR PF01485.21 CAM41852.1 - 0.21 11.8 3.4 0.46 10.7 3.4 1.6 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Zn-ribbon_8 PF09723.10 CAM41852.1 - 0.36 11.0 4.6 0.94 9.6 4.6 1.7 1 0 0 1 1 1 0 Zinc ribbon domain GTP_EFTU PF00009.27 CAM41853.1 - 9.9e-24 83.9 0.2 2.2e-23 82.8 0.2 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.11 CAM41853.1 - 2.7e-12 46.7 0.0 1.2e-11 44.7 0.0 2.2 1 1 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.25 CAM41853.1 - 0.00018 21.8 2.5 0.0012 19.1 0.9 3.0 2 1 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CAM41853.1 - 0.00057 20.0 0.0 0.0023 18.0 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CAM41853.1 - 0.0028 17.6 0.2 0.073 13.0 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase IBR PF01485.21 CAM41853.1 - 0.35 11.1 3.7 0.79 10.0 3.7 1.6 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Zn-ribbon_8 PF09723.10 CAM41853.1 - 0.57 10.3 4.6 1.2 9.3 4.6 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Myosin_tail_1 PF01576.19 CAM41854.1 - 0.0012 16.8 10.5 0.0015 16.5 10.5 1.1 1 0 0 1 1 1 1 Myosin tail DUF4201 PF13870.6 CAM41854.1 - 0.0017 18.1 11.6 0.015 15.1 3.3 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4201) Fez1 PF06818.15 CAM41854.1 - 0.0054 17.2 4.7 0.0054 17.2 4.7 2.0 1 1 1 2 2 2 1 Fez1 Spectrin PF00435.21 CAM41854.1 - 0.0065 16.9 12.8 0.36 11.3 2.4 3.1 2 1 1 3 3 3 1 Spectrin repeat CENP-Q PF13094.6 CAM41854.1 - 0.014 15.6 9.5 0.057 13.6 3.1 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit ZapB PF06005.12 CAM41854.1 - 0.049 14.1 12.2 6.4 7.3 2.7 3.6 3 0 0 3 3 3 0 Cell division protein ZapB SpoVAD PF07451.11 CAM41854.1 - 0.061 12.0 0.1 0.086 11.5 0.1 1.1 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) DUF4472 PF14739.6 CAM41854.1 - 0.086 13.6 9.0 6.1 7.6 0.0 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) FUSC PF04632.12 CAM41854.1 - 0.11 11.1 7.8 0.5 8.8 7.9 1.7 1 1 1 2 2 2 0 Fusaric acid resistance protein family Cnn_1N PF07989.11 CAM41854.1 - 0.14 12.3 11.3 0.15 12.3 1.4 3.5 3 1 0 4 4 3 0 Centrosomin N-terminal motif 1 DUF4200 PF13863.6 CAM41854.1 - 0.14 12.5 11.8 0.31 11.5 3.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) CCDC154 PF15450.6 CAM41854.1 - 0.15 10.6 12.7 0.22 10.0 12.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 154 Mod_r PF07200.13 CAM41854.1 - 0.2 11.8 13.0 0.23 11.5 11.9 1.7 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein GIT_CC PF16559.5 CAM41854.1 - 0.43 10.5 7.7 0.49 10.3 1.5 3.5 2 1 2 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Prominin PF05478.11 CAM41854.1 - 0.51 8.2 7.8 1.7 6.5 7.8 1.6 1 1 0 1 1 1 0 Prominin Cep57_CLD_2 PF14197.6 CAM41854.1 - 0.51 10.5 10.6 0.09 12.9 2.0 3.2 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 CENP-H PF05837.12 CAM41854.1 - 0.57 10.6 15.2 0.11 12.9 6.1 2.7 1 1 2 3 3 3 0 Centromere protein H (CENP-H) zf-C4H2 PF10146.9 CAM41854.1 - 0.81 10.0 6.4 2.2 8.5 5.2 1.9 1 1 1 2 2 2 0 Zinc finger-containing protein DUF4407 PF14362.6 CAM41854.1 - 0.9 8.8 15.3 23 4.2 15.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) LPP PF04728.13 CAM41854.1 - 1.1 9.7 8.4 5.6 7.4 0.1 3.7 2 1 2 4 4 4 0 Lipoprotein leucine-zipper DUF4570 PF15134.6 CAM41854.1 - 1.5 8.9 8.4 3.7 7.6 0.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4570) SlyX PF04102.12 CAM41854.1 - 1.6 9.4 12.9 15 6.3 0.1 3.7 2 1 0 3 3 3 0 SlyX TPR_MLP1_2 PF07926.12 CAM41854.1 - 1.6 8.8 16.5 36 4.4 15.1 3.0 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 CAM41854.1 - 1.9 7.3 14.5 2.9 6.7 12.9 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 CAM41854.1 - 2.1 6.2 5.8 2.6 5.9 5.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LPD5 PF18799.1 CAM41854.1 - 2.1 8.7 8.2 3.6 8.0 5.6 2.4 2 1 0 2 2 2 0 Large polyvalent protein-associated domain 5 Spc24 PF08286.11 CAM41854.1 - 2.9 8.2 15.3 0.43 10.8 3.7 2.8 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 ABC_tran_CTD PF16326.5 CAM41854.1 - 3.4 8.0 14.4 5.2 7.4 4.3 3.4 3 0 0 3 3 3 0 ABC transporter C-terminal domain BRE1 PF08647.11 CAM41854.1 - 3.5 7.8 15.6 0.36 10.9 1.7 2.3 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF1664 PF07889.12 CAM41854.1 - 3.9 7.5 9.1 4.9 7.2 0.9 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DivIC PF04977.15 CAM41854.1 - 4.9 7.0 14.3 4.8 7.0 1.8 3.5 3 0 0 3 3 3 0 Septum formation initiator FliD_N PF02465.18 CAM41854.1 - 5.6 7.7 8.5 5.1 7.8 1.7 2.8 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Fzo_mitofusin PF04799.13 CAM41854.1 - 6.4 6.3 11.2 3.3 7.2 3.1 2.7 2 1 2 4 4 4 0 fzo-like conserved region DHR10 PF18595.1 CAM41854.1 - 6.5 6.8 19.6 0.46 10.6 4.6 2.8 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain UPF0242 PF06785.11 CAM41854.1 - 7.2 6.7 12.6 24 5.0 12.7 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Jnk-SapK_ap_N PF09744.9 CAM41854.1 - 7.3 6.8 15.4 15 5.8 13.3 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF724 PF05266.14 CAM41854.1 - 8.6 6.1 10.9 1.2 8.9 3.7 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF724) TMPIT PF07851.13 CAM41854.1 - 8.6 5.5 9.6 3.1 7.0 2.9 2.1 1 1 1 2 2 2 0 TMPIT-like protein KELK PF15796.5 CAM41854.1 - 9.2 6.8 13.1 0.95 10.0 1.2 2.8 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase LMBR1 PF04791.16 CAM41854.1 - 9.5 5.0 6.0 19 4.0 5.9 1.6 1 1 1 2 2 2 0 LMBR1-like membrane protein Atg14 PF10186.9 CAM41854.1 - 9.8 5.2 11.1 26 3.7 11.1 1.8 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MRP PF09387.10 CAM41856.1 - 9.2e-60 202.0 0.1 1.1e-59 201.7 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial RNA binding protein MRP Tim17 PF02466.19 CAM41857.1 - 5.4e-16 58.9 8.9 8.4e-16 58.3 8.9 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF1069 PF06370.11 CAM41857.1 - 0.032 13.8 0.3 0.05 13.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1069) Hpt PF01627.23 CAM41857.1 - 0.13 12.6 0.1 0.24 11.7 0.1 1.5 1 0 0 1 1 1 0 Hpt domain RRM_1 PF00076.22 CAM41860.2 - 0.17 11.7 0.2 0.47 10.3 0.2 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Skp1 PF01466.19 CAM41861.1 - 1.3e-07 31.6 0.3 3.3e-07 30.3 0.3 1.8 1 0 0 1 1 1 1 Skp1 family, dimerisation domain DUF4670 PF15709.5 CAM41861.1 - 0.05 12.9 0.1 0.077 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4670) Pcc1 PF09341.10 CAM41863.1 - 0.18 12.0 1.0 4.4 7.5 0.3 2.4 2 0 0 2 2 2 0 Transcription factor Pcc1 Ank_5 PF13857.6 CAM41864.1 - 0.013 15.8 0.2 0.063 13.6 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 CAM41864.1 - 0.013 16.1 0.0 0.057 14.0 0.0 2.2 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 CAM41864.1 - 0.014 15.9 0.0 0.12 12.9 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CAM41864.1 - 0.086 13.4 0.2 0.64 10.8 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat zf-C3HC4_3 PF13920.6 CAM41865.1 - 8.9e-09 35.1 22.8 8.9e-09 35.1 22.8 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CAM41865.1 - 5 7.1 30.1 0.1 12.5 22.6 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 AAA PF00004.29 CAM41866.1 - 9.2e-34 116.7 0.0 1.2e-21 77.5 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CAM41866.1 - 6.2e-08 33.0 1.5 0.00081 19.7 0.0 4.0 3 1 1 4 4 3 1 AAA domain AAA_16 PF13191.6 CAM41866.1 - 1.2e-07 32.3 6.4 2.9e-05 24.5 0.0 4.5 4 2 1 5 5 4 1 AAA ATPase domain Zot PF05707.12 CAM41866.1 - 3.8e-07 29.9 0.4 0.076 12.7 0.0 4.3 3 2 2 5 5 4 2 Zonular occludens toxin (Zot) AAA_33 PF13671.6 CAM41866.1 - 8.5e-07 29.2 0.0 0.0086 16.2 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.6 CAM41866.1 - 4.8e-06 26.6 0.0 0.00089 19.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CAM41866.1 - 2e-05 24.4 0.0 0.027 14.2 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein TIP49 PF06068.13 CAM41866.1 - 2.2e-05 23.9 0.1 0.014 14.6 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_5 PF07728.14 CAM41866.1 - 4.4e-05 23.5 0.0 0.0076 16.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CAM41866.1 - 6.1e-05 22.6 0.3 0.0012 18.4 0.1 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 CAM41866.1 - 6.4e-05 23.3 0.0 0.027 14.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase DUF2075 PF09848.9 CAM41866.1 - 0.00012 21.4 0.1 0.74 9.0 0.0 3.3 2 1 1 3 3 3 2 Uncharacterized conserved protein (DUF2075) Bac_DnaA PF00308.18 CAM41866.1 - 0.00037 20.4 0.1 0.0015 18.4 0.0 1.9 2 0 0 2 2 2 1 Bacterial dnaA protein ABC_tran PF00005.27 CAM41866.1 - 0.00055 20.5 0.2 0.051 14.1 0.0 3.0 3 0 0 3 3 2 1 ABC transporter RuvB_N PF05496.12 CAM41866.1 - 0.00093 19.0 0.0 0.085 12.6 0.0 2.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 CAM41866.1 - 0.0011 18.9 0.1 0.085 12.8 0.0 3.0 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 CAM41866.1 - 0.0013 19.3 0.0 0.16 12.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain Torsin PF06309.11 CAM41866.1 - 0.0014 18.8 0.2 0.094 12.8 0.1 2.6 2 0 0 2 2 2 1 Torsin Sigma54_activat PF00158.26 CAM41866.1 - 0.0014 18.3 0.1 0.7 9.6 0.1 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_30 PF13604.6 CAM41866.1 - 0.0026 17.5 0.1 0.24 11.1 0.1 3.0 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CAM41866.1 - 0.0043 16.5 0.2 0.057 12.8 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI PhoH PF02562.16 CAM41866.1 - 0.012 15.1 1.2 0.21 11.0 0.0 2.9 2 1 1 3 3 3 0 PhoH-like protein AAA_2 PF07724.14 CAM41866.1 - 0.018 15.2 0.1 0.22 11.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain (Cdc48 subfamily) PIF1 PF05970.14 CAM41866.1 - 0.018 14.2 0.5 1.3 8.1 0.1 2.9 3 0 0 3 3 3 0 PIF1-like helicase RsgA_GTPase PF03193.16 CAM41866.1 - 0.024 14.6 0.0 0.24 11.3 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase APS_kinase PF01583.20 CAM41866.1 - 0.03 14.2 0.1 0.44 10.4 0.1 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_29 PF13555.6 CAM41866.1 - 0.033 13.9 1.0 2.9 7.7 0.3 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.6 CAM41866.1 - 0.041 14.0 0.0 0.96 9.6 0.0 3.1 4 0 0 4 4 3 0 Sigma-54 interaction domain SRP54 PF00448.22 CAM41866.1 - 0.063 12.9 0.2 0.47 10.1 0.0 2.4 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 CAM41866.1 - 0.069 12.3 0.0 0.21 10.8 0.0 1.8 2 0 0 2 2 1 0 NB-ARC domain ATPase PF06745.13 CAM41866.1 - 0.1 12.0 0.2 6.4 6.1 0.0 2.5 2 0 0 2 2 2 0 KaiC AAA_28 PF13521.6 CAM41866.1 - 0.1 12.8 0.0 2.9 8.1 0.0 3.0 3 0 0 3 3 2 0 AAA domain TsaE PF02367.17 CAM41866.1 - 0.11 12.5 0.3 0.62 10.1 0.2 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DAP3 PF10236.9 CAM41866.1 - 0.15 11.2 0.0 0.58 9.3 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Microtub_bd PF16796.5 CAM41866.1 - 0.18 11.7 0.0 0.44 10.5 0.0 1.6 1 0 0 1 1 1 0 Microtubule binding AAA_12 PF13087.6 CAM41868.2 - 7.7e-49 166.0 0.0 1.4e-48 165.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CAM41868.2 - 4.6e-34 118.4 7.1 7.1e-34 117.8 0.5 3.2 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CAM41868.2 - 1.5e-06 28.1 8.1 0.0031 17.2 0.1 4.1 4 0 0 4 4 4 2 AAA domain AAA_19 PF13245.6 CAM41868.2 - 5.2e-06 26.9 0.0 3.2e-05 24.3 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CAM41868.2 - 0.0016 18.8 0.0 0.052 13.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 CAM41868.2 - 0.0031 17.5 0.0 0.049 13.6 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 CAM41868.2 - 0.04 13.5 0.5 0.42 10.1 0.0 2.5 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 CAM41868.2 - 0.047 13.5 0.0 4.6 7.1 0.0 3.1 2 0 0 2 2 2 0 Helicase FtsK_SpoIIIE PF01580.18 CAM41868.2 - 0.074 12.4 0.8 4.6 6.5 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_16 PF13191.6 CAM41868.2 - 8.2 6.8 7.7 1.5 9.1 0.0 3.9 3 1 0 3 3 3 0 AAA ATPase domain Bromodomain PF00439.25 CAM41870.1 - 3.8e-22 78.1 0.0 1.1e-11 44.6 0.0 2.3 2 0 0 2 2 2 2 Bromodomain MSA-2c PF12238.8 CAM41870.1 - 0.00081 19.5 0.0 0.043 13.8 0.0 2.2 2 0 0 2 2 2 1 Merozoite surface antigen 2c BSD PF03909.17 CAM41870.1 - 0.044 13.8 0.0 7.7 6.6 0.0 2.5 2 0 0 2 2 2 0 BSD domain Mito_carr PF00153.27 CAM41871.1 - 3.8e-44 148.5 6.4 2.9e-17 62.3 0.1 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein Orthopox_C10L PF07020.11 CAM41871.1 - 2.5 8.9 8.4 1.3 9.8 4.7 2.1 2 0 0 2 2 2 0 Orthopoxvirus C10L protein DZR PF12773.7 CAM41872.2 - 5.1e-05 23.2 1.3 0.012 15.6 0.1 2.4 2 0 0 2 2 2 2 Double zinc ribbon zf-FPG_IleRS PF06827.14 CAM41872.2 - 0.036 13.9 2.1 1.4 8.8 0.1 2.7 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS HalOD2 PF18547.1 CAM41872.2 - 2.5 8.1 8.7 20 5.1 0.1 4.0 4 0 0 4 4 4 0 Halobacterial output domain 2 Zn_ribbon_SprT PF17283.2 CAM41872.2 - 5.1 7.1 16.4 0.24 11.3 0.8 3.5 3 1 0 3 3 3 0 SprT-like zinc ribbon domain Kelch_4 PF13418.6 CAM41873.1 - 3.3e-05 23.8 0.0 0.88 9.6 0.0 3.3 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CAM41873.1 - 0.00031 20.7 3.9 0.054 13.5 0.5 3.2 2 1 0 2 2 2 2 Kelch motif Kelch_1 PF01344.25 CAM41873.1 - 0.0011 18.5 0.4 0.92 9.2 0.1 2.7 3 0 0 3 3 3 2 Kelch motif DGOK PF05035.12 CAM41873.1 - 0.024 13.5 0.7 0.027 13.4 0.7 1.2 1 0 0 1 1 1 0 2-keto-3-deoxy-galactonokinase p53-inducible11 PF14936.6 CAM41873.1 - 0.053 13.6 0.0 0.079 13.0 0.0 1.1 1 0 0 1 1 1 0 Tumour protein p53-inducible protein 11 Peptidase_C97 PF05903.14 CAM41874.1 - 5.7e-21 74.9 0.0 8.9e-21 74.3 0.0 1.4 1 1 0 1 1 1 1 PPPDE putative peptidase domain DUF4796 PF16044.5 CAM41874.1 - 0.0024 17.5 0.1 0.0034 17.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4796) Flagellar_rod PF05149.12 CAM41877.1 - 5.7e-109 364.0 18.2 5.7e-109 364.0 18.2 1.9 2 0 0 2 2 2 1 Paraflagellar rod protein FTA4 PF13093.6 CAM41877.1 - 0.13 12.1 5.8 0.2 11.5 3.8 2.4 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Alkyl_sulf_dimr PF14863.6 CAM41877.1 - 7.4 7.0 9.5 53 4.3 5.2 3.4 2 1 0 2 2 2 0 Alkyl sulfatase dimerisation Epiglycanin_C PF14654.6 CAM41878.1 - 0.13 12.4 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Histone PF00125.24 CAM41879.1 - 6.6e-12 45.9 1.8 8.9e-12 45.5 1.8 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CAM41879.1 - 0.00018 21.7 0.2 0.00036 20.7 0.2 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone F-box PF00646.33 CAM41883.1 - 0.045 13.7 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 F-box domain Glyco_hydro_47 PF01532.20 CAM41884.1 - 8.1e-08 31.6 0.0 1.4e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 SET PF00856.28 CAM41885.1 - 5.9e-12 46.3 0.0 1.8e-11 44.7 0.0 2.0 2 1 0 2 2 2 1 SET domain Prominin PF05478.11 CAM41886.2 - 0.16 9.9 0.4 0.17 9.8 0.4 1.1 1 0 0 1 1 1 0 Prominin DUF572 PF04502.13 CAM41886.2 - 0.4 10.2 9.9 0.54 9.8 9.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) FAM178 PF14816.6 CAM41886.2 - 0.55 9.2 3.8 0.56 9.1 3.8 1.3 1 0 0 1 1 1 0 Family of unknown function, FAM178 DUF4570 PF15134.6 CAM41886.2 - 0.56 10.2 7.7 0.029 14.4 2.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) L31 PF09784.9 CAM41886.2 - 0.75 10.3 5.1 0.79 10.2 4.2 1.7 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L31 DUF4407 PF14362.6 CAM41886.2 - 1.2 8.5 6.7 1.6 8.0 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 CAM41886.2 - 1.5 6.7 6.6 1.6 6.6 6.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Coq4 PF05019.13 CAM41887.1 - 7.5e-48 162.8 0.0 8.4e-48 162.6 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 PCSK9_C2 PF18464.1 CAM41887.1 - 0.043 13.8 0.1 0.091 12.8 0.1 1.5 1 0 0 1 1 1 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain DnaJ PF00226.31 CAM41888.2 - 5.5e-12 45.6 0.1 1.1e-11 44.6 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain GcrA PF07750.11 CAM41888.2 - 0.01 16.2 0.0 0.023 15.1 0.0 1.6 1 0 0 1 1 1 0 GcrA cell cycle regulator PHA_synth_III_E PF09712.10 CAM41888.2 - 0.029 13.5 1.0 0.17 10.9 0.3 1.9 2 0 0 2 2 2 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Rhodanese PF00581.20 CAM41889.1 - 0.00056 20.4 0.0 0.00068 20.1 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain LisH PF08513.11 CAM41889.1 - 0.14 12.2 0.1 1.2 9.2 0.0 2.2 1 1 1 2 2 2 0 LisH Rhodanese PF00581.20 CAM41890.1 - 1.4e-10 41.6 0.0 1.9e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain HTH_18 PF12833.7 CAM41890.1 - 0.063 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain S8_pro-domain PF16470.5 CAM41890.1 - 0.2 12.4 0.0 0.31 11.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase S8 pro-domain Rhodanese PF00581.20 CAM41891.1 - 1.3e-15 57.8 0.0 1.5e-15 57.6 0.0 1.0 1 0 0 1 1 1 1 Rhodanese-like domain DUF4859 PF16151.5 CAM41891.1 - 0.0064 16.4 0.0 0.0088 15.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4859) Mito_carr PF00153.27 CAM41891.1 - 0.077 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial carrier protein DB_JBP1 PF18526.1 CAM41892.1 - 6.7e-86 286.3 5.5 6.7e-86 286.3 5.5 1.7 2 0 0 2 2 2 1 Thymine dioxygenase JBP1 DNA-binding domain Tet_JBP PF12851.7 CAM41892.1 - 1.6e-20 73.7 0.3 2.2e-16 60.1 0.0 2.7 2 1 1 3 3 3 2 Oxygenase domain of the 2OGFeDO superfamily Cyt-b5 PF00173.28 CAM41893.1 - 3.3e-21 75.2 0.3 4.2e-21 74.9 0.3 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CPT PF07931.12 CAM41896.1 - 0.065 13.1 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein UPF0180 PF03698.13 CAM41896.1 - 0.16 12.2 0.0 0.41 10.8 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) LRR_6 PF13516.6 CAM41897.1 - 4.3e-14 51.3 1.1 0.033 14.2 0.0 6.6 7 0 0 7 7 7 3 Leucine Rich repeat EF-hand_6 PF13405.6 CAM41898.1 - 0.00052 19.7 0.0 0.027 14.4 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 CAM41898.1 - 0.0017 18.8 0.0 0.0028 18.1 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CAM41898.1 - 0.0046 16.4 0.0 0.032 13.8 0.0 2.3 2 0 0 2 2 2 1 EF hand RIIa PF02197.17 CAM41898.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit Pheromone PF08015.11 CAM41898.1 - 0.17 13.0 0.9 0.36 11.9 0.3 1.9 1 1 1 2 2 2 0 Fungal mating-type pheromone KASH_CCD PF14662.6 CAM41899.2 - 3.4e-06 27.0 88.1 0.016 15.0 18.0 5.8 2 2 2 5 5 5 5 Coiled-coil region of CCDC155 or KASH KELK PF15796.5 CAM41899.2 - 0.021 15.2 3.9 0.021 15.2 3.9 8.1 5 2 3 8 8 8 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase ADIP PF11559.8 CAM41899.2 - 5.6 7.0 96.1 0.057 13.5 16.3 8.1 2 2 6 9 9 9 0 Afadin- and alpha -actinin-Binding PIF1 PF05970.14 CAM41901.1 - 3.4e-29 102.1 2.0 3.1e-22 79.2 1.0 3.7 3 1 0 3 3 3 3 PIF1-like helicase AAA_30 PF13604.6 CAM41901.1 - 7.4e-19 68.2 0.0 2e-18 66.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CAM41901.1 - 2.1e-05 24.9 1.7 4.5e-05 23.8 0.1 2.3 2 1 0 2 2 2 1 AAA domain Herpes_Helicase PF02689.14 CAM41901.1 - 0.0013 16.8 0.1 0.79 7.6 0.0 2.6 3 0 0 3 3 3 2 Helicase AAA_22 PF13401.6 CAM41901.1 - 0.0016 18.7 1.4 1.9 8.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain DUF853 PF05872.12 CAM41901.1 - 0.0016 17.1 1.0 0.0032 16.1 1.0 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) UvrD_C_2 PF13538.6 CAM41901.1 - 0.015 15.1 0.4 0.1 12.4 0.4 2.3 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_11 PF13086.6 CAM41901.1 - 0.055 13.3 4.7 4.4 7.0 0.1 3.5 2 1 1 3 3 3 0 AAA domain AAA_5 PF07728.14 CAM41901.1 - 0.1 12.6 0.0 0.31 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CAM41901.1 - 0.17 12.3 1.7 0.53 10.7 0.2 2.6 2 0 0 2 2 2 0 AAA ATPase domain Viral_helicase1 PF01443.18 CAM41901.1 - 0.2 11.3 1.2 10 5.8 0.0 3.1 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 CAM41901.1 - 1.7 9.2 3.4 0.87 10.1 0.4 2.1 2 0 0 2 2 1 0 ABC transporter PIF1 PF05970.14 CAM41902.1 - 2.5e-35 122.3 0.7 6.6e-28 97.9 0.1 3.5 2 1 1 3 3 3 3 PIF1-like helicase AAA_30 PF13604.6 CAM41902.1 - 6.1e-18 65.2 0.1 2.4e-17 63.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CAM41902.1 - 5.7e-06 26.7 0.1 2.9e-05 24.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CAM41902.1 - 0.0014 18.4 0.4 1.4 8.6 0.1 3.2 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 CAM41902.1 - 0.0017 18.8 0.0 0.0074 16.7 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 CAM41902.1 - 0.0054 16.1 0.2 0.013 14.9 0.2 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 CAM41902.1 - 0.0061 16.8 0.6 0.13 12.5 0.6 2.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 CAM41902.1 - 0.0077 16.6 0.0 0.023 15.1 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 CAM41902.1 - 0.0083 15.9 1.3 0.059 13.1 0.0 2.8 2 1 0 3 3 3 1 AAA domain UvrD_C_2 PF13538.6 CAM41902.1 - 0.024 14.4 1.5 0.1 12.4 0.4 2.6 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA_5 PF07728.14 CAM41902.1 - 0.025 14.6 0.0 0.085 12.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Herpes_Helicase PF02689.14 CAM41902.1 - 0.026 12.5 0.3 0.15 10.0 0.0 1.9 2 0 0 2 2 2 0 Helicase DinB_2 PF12867.7 CAM41902.1 - 0.073 13.6 0.8 0.81 10.2 0.1 3.0 4 0 0 4 4 3 0 DinB superfamily PhoH PF02562.16 CAM41902.1 - 0.078 12.4 0.0 0.25 10.8 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 CAM41902.1 - 0.16 11.9 0.1 0.34 10.8 0.1 1.5 1 0 0 1 1 1 0 NACHT domain DUF5349 PF17298.2 CAM41903.1 - 0.54 10.0 4.1 0.15 11.8 0.5 2.0 3 0 0 3 3 3 0 Family of unknown function (DUF5349) 14-3-3 PF00244.20 CAM41904.1 - 1.9e-83 279.4 1.3 2.2e-83 279.2 1.3 1.0 1 0 0 1 1 1 1 14-3-3 protein RE_XcyI PF09571.10 CAM41904.1 - 0.09 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 XcyI restriction endonuclease OPA3 PF07047.12 CAM41905.1 - 1.6e-19 69.9 2.6 1.9e-18 66.5 2.6 2.2 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) DUF2779 PF11074.8 CAM41907.1 - 8e-37 126.5 0.0 1.4e-36 125.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function(DUF2779) DUF3450 PF11932.8 CAM41907.1 - 0.54 9.5 7.1 1 8.6 7.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TTL PF03133.15 CAM41908.1 - 4.3e-67 226.3 0.0 6.7e-67 225.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CAM41908.1 - 5.1e-08 32.5 0.1 0.0005 19.4 0.0 3.2 2 1 1 3 3 3 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CAM41908.1 - 0.0003 20.1 0.0 0.086 12.1 0.0 2.4 2 1 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 CAM41908.1 - 0.048 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain BOP1NT PF08145.12 CAM41909.1 - 4.2e-78 262.8 7.4 6.9e-78 262.2 7.4 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 CAM41909.1 - 7.4e-18 64.6 4.7 8.9e-08 32.7 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM41909.1 - 9.6e-08 32.2 0.0 0.00079 19.7 0.0 4.5 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CAM41909.1 - 0.023 13.6 0.0 0.87 8.5 0.0 2.6 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RCC1 PF00415.18 CAM41910.1 - 1.3e-21 77.0 19.8 7.2e-07 29.7 0.0 8.2 7 2 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CAM41910.1 - 6.2e-11 41.8 28.3 9.8e-07 28.4 0.5 6.4 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat LRR_4 PF12799.7 CAM41912.1 - 1.9e-13 50.4 13.2 0.00013 22.2 0.3 4.0 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM41912.1 - 3.8e-08 33.0 21.1 0.0005 19.8 4.2 4.2 2 1 2 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 CAM41912.1 - 0.0016 18.0 0.3 0.028 13.9 0.2 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 CAM41912.1 - 0.025 15.1 15.9 11 7.1 0.1 6.3 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 CAM41912.1 - 0.067 13.3 19.9 0.2 11.8 0.8 4.8 6 0 0 6 6 6 0 Leucine Rich repeat DNA_ligase_A_M PF01068.21 CAM41913.1 - 0.022 14.4 0.0 6.3 6.4 0.0 3.3 4 0 0 4 4 4 0 ATP dependent DNA ligase domain DNA_ligase_OB_2 PF14743.6 CAM41913.1 - 0.059 13.4 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 DNA ligase OB-like domain PUF PF00806.19 CAM41915.1 - 2.9e-10 39.3 0.0 0.042 13.5 0.0 5.8 5 0 0 5 5 5 3 Pumilio-family RNA binding repeat CPL PF08144.11 CAM41915.1 - 0.0052 17.1 4.2 0.093 13.1 0.1 4.3 3 2 0 3 3 3 1 CPL (NUC119) domain Pox_MCEL PF03291.16 CAM41918.1 - 1.8e-14 53.6 0.0 2.9e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 CAM41918.1 - 1.1e-07 32.5 0.0 4.9e-07 30.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAM41918.1 - 1.3e-05 25.7 0.0 6.1e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAM41918.1 - 0.00014 22.6 0.0 0.00037 21.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAM41918.1 - 0.0026 17.6 0.0 0.0052 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NSP16 PF06460.12 CAM41918.1 - 0.012 14.8 0.1 0.02 14.0 0.1 1.2 1 0 0 1 1 1 0 Coronavirus NSP16 PHF5 PF03660.14 CAM41918.1 - 0.089 13.0 2.6 0.14 12.3 1.3 2.0 2 0 0 2 2 2 0 PHF5-like protein zf-CHY PF05495.12 CAM41918.1 - 0.41 11.2 6.3 0.99 9.9 6.3 1.6 1 0 0 1 1 1 0 CHY zinc finger CEBP_ZZ PF16366.5 CAM41918.1 - 5.6 7.3 9.5 37 4.6 4.7 2.9 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain TPR_1 PF00515.28 CAM41919.1 - 5e-18 64.1 4.9 0.00018 21.2 0.3 6.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 CAM41919.1 - 1.5e-16 59.0 6.3 7.4e-05 22.6 0.0 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 CAM41919.1 - 3.5e-16 58.6 0.7 2.1e-05 24.1 0.0 4.4 3 1 1 4 4 4 3 TPR repeat TPR_12 PF13424.6 CAM41919.1 - 4.7e-10 39.6 5.1 0.0011 19.2 0.1 5.3 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 CAM41919.1 - 1.4e-08 35.3 1.9 0.004 17.8 0.1 5.1 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 CAM41919.1 - 1.9e-08 33.8 7.4 0.0084 16.3 0.5 6.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 CAM41919.1 - 4.8e-08 32.8 3.3 0.12 12.8 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 CAM41919.1 - 2.2e-07 31.3 0.8 0.1 13.1 0.0 4.6 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 CAM41919.1 - 1.7e-06 27.6 0.0 0.017 15.1 0.0 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CAM41919.1 - 5.4e-06 26.8 2.2 0.65 11.0 0.0 4.7 2 2 2 4 4 4 2 Tetratricopeptide repeat DUF3808 PF10300.9 CAM41919.1 - 0.00047 19.0 0.2 0.0024 16.7 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_MalT PF17874.1 CAM41919.1 - 0.0023 17.4 0.3 0.32 10.3 0.0 2.8 2 1 0 2 2 2 1 MalT-like TPR region TPR_6 PF13174.6 CAM41919.1 - 0.0025 18.3 5.7 0.76 10.5 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 CAM41919.1 - 0.012 15.5 1.7 0.11 12.4 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CAM41919.1 - 0.034 14.4 1.8 4.6 7.5 0.1 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 HYLS1_C PF15311.6 CAM41919.1 - 0.087 13.6 0.0 0.21 12.3 0.0 1.6 1 0 0 1 1 1 0 Hydrolethalus syndrome protein 1 C-terminus MIT PF04212.18 CAM41919.1 - 1.9 8.6 12.8 4.7 7.4 0.0 4.4 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TMEM192 PF14802.6 CAM41921.1 - 0.13 11.3 1.1 0.2 10.8 1.1 1.1 1 0 0 1 1 1 0 TMEM192 family DUF3682 PF12446.8 CAM41921.1 - 4.7 7.7 9.5 8.2 6.9 9.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3682) BING4CT PF08149.11 CAM41923.1 - 3.4e-29 100.5 0.2 2.5e-28 97.7 0.0 2.5 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.32 CAM41923.1 - 6.8e-07 29.9 0.9 5.9e-06 26.9 0.0 2.8 3 0 0 3 3 3 1 WD domain, G-beta repeat Sec10 PF07393.11 CAM41924.1 - 4.1e-28 98.2 7.3 5.2e-26 91.3 0.1 3.1 3 0 0 3 3 3 2 Exocyst complex component Sec10 Peptidase_S46 PF10459.9 CAM41924.1 - 0.025 13.2 0.5 0.045 12.4 0.5 1.3 1 0 0 1 1 1 0 Peptidase S46 Spc7 PF08317.11 CAM41924.1 - 0.32 9.8 2.1 0.64 8.8 2.1 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein PepSY_TM_like_2 PF16357.5 CAM41925.1 - 0.055 13.5 0.2 0.13 12.2 0.2 1.6 1 0 0 1 1 1 0 Putative PepSY_TM-like DUF3302 PF11742.8 CAM41925.1 - 0.059 13.5 0.0 0.059 13.5 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3302) tRNA_anti-like PF12869.7 CAM41925.1 - 0.098 12.3 2.7 0.83 9.3 1.0 2.7 2 0 0 2 2 2 0 tRNA_anti-like UPF0242 PF06785.11 CAM41925.1 - 1.1 9.3 6.5 2.2 8.3 6.5 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus IFT20 PF14931.6 CAM41925.1 - 2.3 8.4 11.9 0.84 9.8 9.2 1.7 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 ERM PF00769.19 CAM41925.1 - 4.4 7.0 30.5 12 5.6 30.6 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF2517 PF10725.9 CAM41925.1 - 5.4 6.9 6.2 0.56 10.0 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2517) CDC45 PF02724.14 CAM41925.1 - 6.3 5.0 11.4 8.7 4.5 11.4 1.1 1 0 0 1 1 1 0 CDC45-like protein ADP_ribosyl_GH PF03747.14 CAM41925.1 - 6.4 6.4 10.7 14 5.3 10.7 1.6 1 1 0 1 1 1 0 ADP-ribosylglycohydrolase Pkinase PF00069.25 CAM41928.1 - 5.7e-31 107.8 0.0 1.4e-30 106.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM41928.1 - 8.6e-14 51.4 0.1 4.9e-12 45.7 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 CAM41928.1 - 0.00045 19.9 0.2 0.00097 18.8 0.0 1.6 2 0 0 2 2 2 1 RIO1 family Pox_ser-thr_kin PF05445.11 CAM41928.1 - 0.0014 17.6 0.0 0.0021 17.1 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 CAM41928.1 - 0.0043 15.9 0.0 0.0052 15.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CAM41928.1 - 0.1 11.9 0.2 0.4 9.9 0.0 2.0 3 0 0 3 3 3 0 Kinase-like Choline_kinase PF01633.20 CAM41928.1 - 0.19 11.3 0.1 0.39 10.3 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase AA_permease_2 PF13520.6 CAM41929.1 - 3.2e-19 69.1 37.2 3.2e-19 69.1 37.2 1.4 1 1 0 1 1 1 1 Amino acid permease DUF563 PF04577.14 CAM41931.1 - 1.1e-11 45.2 0.1 4.8e-11 43.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF563) Nucleoside_tran PF01733.18 CAM41932.1 - 1.1e-32 113.7 13.4 7.3e-25 88.0 0.0 2.7 2 1 1 3 3 3 2 Nucleoside transporter FA_desaturase PF00487.24 CAM41933.1 - 5e-14 52.7 24.3 1.1e-13 51.6 24.3 1.6 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 CAM41933.1 - 6e-09 35.9 0.0 6.4e-08 32.6 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain 5TM-5TMR_LYT PF07694.12 CAM41933.1 - 0.02 14.4 2.5 0.042 13.4 0.5 2.2 2 0 0 2 2 2 0 5TMR of 5TMR-LYT Collectrin PF16959.5 CAM41933.1 - 0.033 13.9 0.1 0.083 12.7 0.1 1.6 1 0 0 1 1 1 0 Renal amino acid transporter MerC PF03203.14 CAM41933.1 - 0.32 11.5 6.3 0.12 12.8 1.0 2.4 2 0 0 2 2 2 0 MerC mercury resistance protein SH3_9 PF14604.6 CAM41934.1 - 0.019 14.8 0.0 0.15 11.9 0.0 2.3 1 1 0 1 1 1 0 Variant SH3 domain DUF5082 PF16888.5 CAM41934.1 - 0.21 11.9 2.2 2.1 8.7 0.7 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) SRC-1 PF08832.10 CAM41934.1 - 0.8 10.8 0.0 0.8 10.8 0.0 4.3 4 2 0 4 4 4 0 Steroid receptor coactivator UPF0242 PF06785.11 CAM41934.1 - 2.4 8.2 8.9 3.3 7.8 4.6 2.6 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 CAM41934.1 - 3.4 6.5 11.6 14 4.4 0.1 3.4 3 1 0 3 3 3 0 Spc7 kinetochore protein Hemerythrin PF01814.23 CAM41934.1 - 4.3 8.0 9.0 0.76 10.4 1.4 3.2 3 1 0 3 3 3 0 Hemerythrin HHE cation binding domain zf-C4H2 PF10146.9 CAM41934.1 - 6.7 7.0 7.7 24 5.2 0.1 3.4 3 2 1 4 4 4 0 Zinc finger-containing protein Tex_N PF09371.10 CAM41935.2 - 6.3e-38 130.3 0.0 1.4e-37 129.1 0.0 1.6 1 0 0 1 1 1 1 Tex-like protein N-terminal domain Tex_YqgF PF16921.5 CAM41935.2 - 1e-32 113.2 0.1 2.5e-32 112.0 0.1 1.7 1 0 0 1 1 1 1 Tex protein YqgF-like domain HHH_9 PF17674.1 CAM41935.2 - 2.5e-11 44.3 0.9 2.4e-09 38.0 0.3 3.4 2 1 0 2 2 2 1 HHH domain HHH_3 PF12836.7 CAM41935.2 - 2e-09 37.6 0.0 4.5e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 CAM41935.2 - 1.1e-06 28.4 0.0 2.8e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 CAM41935.2 - 0.0028 18.0 0.0 0.0065 16.8 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif S1 PF00575.23 CAM41935.2 - 0.048 14.0 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 S1 RNA binding domain ArgoL2 PF16488.5 CAM41936.1 - 2.1e-11 44.0 0.2 5.5e-11 42.6 0.2 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 CAM41936.1 - 1.1e-07 31.7 0.0 2.5e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 PAZ domain Piwi PF02171.17 CAM41936.1 - 2.8e-07 30.1 0.1 2.5e-06 26.9 0.1 2.1 1 1 0 1 1 1 1 Piwi domain ArgoN PF16486.5 CAM41936.1 - 0.00027 21.6 0.0 0.00062 20.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute Carboxyl_trans PF01039.22 CAM41937.1 - 1.2e-141 472.7 0.0 1.8e-141 472.2 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 CAM41937.1 - 4.4e-05 23.1 0.1 0.16 11.4 0.0 2.4 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) zf-C4H2 PF10146.9 CAM41938.2 - 0.14 12.4 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein Pdase_M17_N2 PF18295.1 CAM41940.1 - 2.6e-26 92.3 3.1 2.6e-26 92.3 3.1 1.5 2 0 0 2 2 2 1 M17 aminopeptidase N-terminal domain 2 Ribosomal_S11 PF00411.19 CAM41940.1 - 0.0059 17.0 0.8 0.01 16.2 0.8 1.4 1 0 0 1 1 1 1 Ribosomal protein S11 ESX-1_EspG PF14011.6 CAM41940.1 - 0.0089 15.7 5.3 0.011 15.3 5.3 1.3 1 0 0 1 1 1 1 EspG family Peptidase_M17 PF00883.21 CAM41941.1 - 4.1e-88 295.7 0.6 5.7e-88 295.2 0.6 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Pdase_M17_N2 PF18295.1 CAM41941.1 - 1.2e-30 106.2 4.4 1.4e-30 106.0 1.7 2.4 2 0 0 2 2 2 1 M17 aminopeptidase N-terminal domain 2 ESX-1_EspG PF14011.6 CAM41941.1 - 0.034 13.7 5.6 0.057 13.0 5.6 1.3 1 0 0 1 1 1 0 EspG family 30K_MP_C_Ter PF11330.8 CAM41941.1 - 0.051 12.9 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 C-Terminal of 30K viral movement proteins Mito_carr PF00153.27 CAM41942.1 - 0.15 11.9 0.1 0.7 9.9 0.1 2.1 1 0 0 1 1 1 0 Mitochondrial carrier protein MFS_1 PF07690.16 CAM41943.1 - 3e-22 79.0 36.4 1.1e-18 67.3 21.9 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 CAM41943.1 - 7.9e-10 38.6 10.9 4e-09 36.3 10.9 2.2 1 1 0 1 1 1 1 Nodulin-like Nodulin-like PF06813.13 CAM41944.2 - 2.7e-08 33.6 12.5 2.7e-08 33.6 12.5 2.9 2 2 0 2 2 2 1 Nodulin-like MotA_ExbB PF01618.16 CAM41944.2 - 0.9 9.3 0.0 0.9 9.3 0.0 2.4 3 0 0 3 3 3 0 MotA/TolQ/ExbB proton channel family Cyt-b5 PF00173.28 CAM41946.1 - 8.5e-19 67.5 0.1 2e-18 66.3 0.0 1.5 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Nodulin-like PF06813.13 CAM41947.1 - 1.1e-07 31.7 26.1 1.8e-07 31.0 18.0 3.3 2 1 1 3 3 3 2 Nodulin-like Ank_4 PF13637.6 CAM41948.1 - 1.6e-23 82.7 1.0 7.1e-07 29.7 0.0 4.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 CAM41948.1 - 4.3e-22 78.5 0.6 2.9e-10 40.6 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CAM41948.1 - 9.5e-17 60.9 2.6 0.00013 22.2 0.0 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 CAM41948.1 - 2.1e-15 56.4 0.6 0.00063 20.1 0.0 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 CAM41948.1 - 9.8e-15 53.2 0.6 0.002 18.5 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat DpaA_N PF16924.5 CAM41948.1 - 0.016 15.3 0.6 0.42 10.7 0.1 2.8 3 1 1 4 4 4 0 Dipicolinate synthase subunit A N-terminal domain Ad_Cy_reg PF16701.5 CAM41948.1 - 0.035 13.8 0.1 0.19 11.4 0.0 2.0 1 1 1 2 2 2 0 Adenylate cyclase regulatory domain Amidinotransf PF02274.17 CAM41948.1 - 0.08 12.0 0.4 9 5.3 0.0 2.7 2 1 0 3 3 3 0 Amidinotransferase ArsA_ATPase PF02374.15 CAM41949.1 - 1.8e-88 296.7 0.0 6.9e-49 166.7 0.0 2.2 2 0 0 2 2 2 2 Anion-transporting ATPase AAA_31 PF13614.6 CAM41949.1 - 9.6e-08 32.1 0.0 5.9e-07 29.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 CAM41949.1 - 5.4e-07 29.7 0.1 4.4e-06 26.8 0.1 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 CAM41949.1 - 0.0082 15.6 0.1 0.029 13.8 0.1 1.8 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 CAM41949.1 - 0.0094 15.6 0.1 2.2 7.9 0.1 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_25 PF13481.6 CAM41949.1 - 0.02 14.5 0.0 0.044 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.18 CAM41949.1 - 0.053 13.0 0.0 0.64 9.4 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NB-ARC PF00931.22 CAM41949.1 - 0.1 11.8 0.1 0.19 10.9 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain VEK-30 PF12107.8 CAM41950.1 - 0.0067 16.3 2.6 0.12 12.3 2.5 2.9 2 0 0 2 2 2 1 Plasminogen (Pg) ligand in fibrinolytic pathway Peptidase_C11 PF03415.14 CAM41951.1 - 2.3e-07 30.5 0.0 3.2e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Clostripain family DUF1541 PF07563.11 CAM41953.1 - 0.22 11.4 1.4 5 7.1 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1541) Ribosomal_S21e PF01249.18 CAM41955.1 - 3.4e-33 113.6 0.2 4.4e-33 113.2 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S21e Amelotin PF15757.5 CAM41955.1 - 1.2 8.6 6.2 4.2 6.9 6.2 1.9 1 1 0 1 1 1 0 Amelotin Ribosomal_S21e PF01249.18 CAM41956.1 - 3.4e-33 113.6 0.2 4.4e-33 113.2 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S21e Amelotin PF15757.5 CAM41956.1 - 1.2 8.6 6.2 4.2 6.9 6.2 1.9 1 1 0 1 1 1 0 Amelotin COX6B PF02297.17 CAM41957.1 - 0.0001 22.5 9.9 0.024 14.9 1.8 2.8 1 1 1 2 2 2 2 Cytochrome oxidase c subunit VIb CX9C PF16860.5 CAM41957.1 - 1.4 9.0 9.1 7.7 6.6 0.1 3.3 3 1 0 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 CAM41957.1 - 2.5 8.5 8.1 15 6.0 0.4 3.2 3 0 0 3 3 3 0 Cytochrome c oxidase assembly protein PET191 EF-hand_6 PF13405.6 CAM41959.1 - 1.3e-13 49.7 0.0 0.22 11.6 0.0 7.2 8 0 0 8 8 8 4 EF-hand domain EF-hand_7 PF13499.6 CAM41959.1 - 2.7e-09 37.4 0.0 1.5 9.4 0.0 6.1 6 0 0 6 6 6 3 EF-hand domain pair EF-hand_1 PF00036.32 CAM41959.1 - 0.00022 20.6 0.0 7.2 6.4 0.0 5.0 6 0 0 6 6 6 2 EF hand EF-hand_8 PF13833.6 CAM41959.1 - 0.023 14.5 0.0 35 4.3 0.0 4.9 6 0 0 6 6 6 0 EF-hand domain pair EF-hand_11 PF08976.11 CAM41959.1 - 0.058 14.3 0.0 47 4.9 0.0 4.6 5 0 0 5 5 5 0 EF-hand domain DUF3552 PF12072.8 CAM41960.1 - 0.00092 18.7 13.4 0.0014 18.1 13.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) Poty_PP PF08440.10 CAM41960.1 - 0.2 10.7 4.3 0.28 10.2 4.3 1.1 1 0 0 1 1 1 0 Potyviridae polyprotein APG6_N PF17675.1 CAM41960.1 - 0.75 10.3 18.5 1.1 9.7 18.5 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Exonuc_VII_L PF02601.15 CAM41960.1 - 1.7 8.2 12.4 2.5 7.6 12.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Jnk-SapK_ap_N PF09744.9 CAM41960.1 - 1.8 8.8 14.4 3.5 7.8 14.4 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 ALMT PF11744.8 CAM41960.1 - 2.5 6.8 5.0 3.4 6.4 5.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter V_ATPase_I PF01496.19 CAM41960.1 - 4 5.2 8.6 5.2 4.9 8.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family OmpH PF03938.14 CAM41960.1 - 6.3 7.1 23.9 12 6.3 23.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TTL PF03133.15 CAM41962.1 - 0.08 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Tubulin-tyrosine ligase family LRS4 PF10422.9 CAM41963.1 - 0.05 13.2 8.1 0.13 11.8 8.1 1.7 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Spc7 PF08317.11 CAM41963.1 - 0.44 9.4 11.8 0.77 8.6 11.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_13 PF13166.6 CAM41963.1 - 0.57 8.8 10.1 0.86 8.2 10.1 1.1 1 0 0 1 1 1 0 AAA domain DUF2203 PF09969.9 CAM41963.1 - 0.91 10.3 5.7 2.6 8.8 5.7 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) TMF_DNA_bd PF12329.8 CAM41963.1 - 1 9.4 23.0 0.014 15.4 13.6 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding FapA PF03961.13 CAM41963.1 - 1.1 7.7 6.8 1.8 7.1 6.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A LCD1 PF09798.9 CAM41963.1 - 6.7 5.1 7.8 9.9 4.5 7.8 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein BshC PF10079.9 CAM41963.1 - 7.3 5.2 9.4 12 4.5 9.4 1.2 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC Abhydrolase_6 PF12697.7 CAM41964.1 - 2.4e-06 28.3 2.4 5.4e-06 27.2 2.4 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CAM41964.1 - 9.9e-06 25.4 0.1 0.00019 21.2 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CAM41964.1 - 0.0003 20.1 0.0 0.0089 15.3 0.0 2.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Palm_thioest PF02089.15 CAM41964.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase HEAT PF02985.22 CAM41966.1 - 0.27 11.6 12.3 2.5 8.6 0.0 6.4 7 0 0 7 7 7 0 HEAT repeat Kinesin PF00225.23 CAM41967.1 - 1.3e-87 293.9 0.0 1.5e-86 290.3 0.0 2.2 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CAM41967.1 - 1.1e-21 77.3 0.0 2.4e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding KELK PF15796.5 CAM41967.1 - 4.9 7.7 11.5 0.24 11.9 3.7 2.5 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase START PF01852.19 CAM41968.1 - 1.2e-19 70.5 0.0 2.3e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 START domain DUF3074 PF11274.8 CAM41968.1 - 0.041 13.8 0.1 0.34 10.9 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3074) LRR_6 PF13516.6 CAM41969.2 - 1.2e-20 71.7 19.1 0.0035 17.3 0.1 11.6 11 0 0 11 11 11 8 Leucine Rich repeat LRR_4 PF12799.7 CAM41969.2 - 5.8e-08 32.9 21.1 0.37 11.3 0.0 8.8 7 1 4 11 11 11 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CAM41969.2 - 9.9e-08 31.5 13.6 15 6.6 0.0 10.4 11 1 0 11 11 11 2 Leucine Rich Repeat LRR_8 PF13855.6 CAM41969.2 - 7.4e-07 28.8 25.7 0.045 13.5 4.1 8.1 9 2 0 9 9 9 4 Leucine rich repeat Ribosomal_L24e PF01246.20 CAM41970.1 - 1.1e-31 108.9 4.2 1.1e-31 108.9 4.2 2.5 2 0 0 2 2 2 1 Ribosomal protein L24e zf-FCS PF06467.14 CAM41970.1 - 0.19 11.7 6.4 0.36 10.8 6.4 1.4 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif AAA PF00004.29 CAM41971.1 - 2.9e-39 134.5 0.0 1.1e-38 132.6 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAM41971.1 - 1e-10 41.3 0.2 5.5e-10 38.9 0.0 2.3 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 CAM41971.1 - 8.3e-05 23.0 2.9 0.00031 21.2 1.2 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CAM41971.1 - 0.00014 22.1 0.0 0.00041 20.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 CAM41971.1 - 0.00016 21.8 0.0 0.00037 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CAM41971.1 - 0.0042 17.1 0.1 0.042 13.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CAM41971.1 - 0.02 15.0 0.0 0.087 13.0 0.0 2.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CAM41971.1 - 0.035 13.8 0.0 0.08 12.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 CAM41971.1 - 0.046 14.3 0.1 0.2 12.2 0.0 2.2 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 CAM41971.1 - 0.053 13.8 0.0 0.22 11.8 0.0 2.2 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CAM41971.1 - 0.053 12.9 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 CAM41971.1 - 0.072 12.8 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 CAM41971.1 - 0.085 12.4 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PUB PF09409.10 CAM41972.1 - 2.1e-08 34.0 0.0 4.1e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 PUB domain SHOCT PF09851.9 CAM41972.1 - 0.007 16.1 2.4 0.0076 15.9 0.2 2.3 2 0 0 2 2 2 1 Short C-terminal domain hnRNP_Q_AcD PF18360.1 CAM41972.1 - 0.11 12.5 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain Novirhabdo_Nv PF05554.11 CAM41972.1 - 0.13 12.0 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 Viral hemorrhagic septicemia virus non-virion protein BT1 PF03092.16 CAM41972.1 - 3.5 5.7 3.8 14 3.8 1.4 2.0 2 0 0 2 2 2 0 BT1 family Surp PF01805.20 CAM41973.1 - 0.0011 18.9 0.0 0.0038 17.2 0.0 1.9 1 0 0 1 1 1 1 Surp module SPT6_acidic PF14632.6 CAM41975.1 - 0.21 12.2 0.0 0.21 12.2 0.0 2.5 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Ribosomal_S7 PF00177.21 CAM41976.1 - 3.2e-34 117.7 1.0 4e-34 117.4 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosomal_S7 PF00177.21 CAM41977.1 - 1.2e-32 112.6 0.4 1.3e-32 112.5 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e zf-HIT PF04438.16 CAM41978.1 - 5.8e-08 32.5 6.6 1.1e-07 31.5 6.6 1.5 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 CAM41978.1 - 0.014 15.4 3.9 0.034 14.2 3.9 1.6 1 0 0 1 1 1 0 MYND finger Adaptin_N PF01602.20 CAM41979.1 - 3.7e-81 273.3 0.0 5e-81 272.8 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CAM41979.1 - 1.3e-17 64.3 0.0 1.3e-16 61.0 0.0 2.8 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CAM41979.1 - 1e-06 29.0 4.0 0.051 14.0 0.2 5.2 3 2 2 6 6 6 3 HEAT repeats HEAT_EZ PF13513.6 CAM41979.1 - 0.0075 16.7 4.8 0.1 13.1 0.0 4.9 6 0 0 6 6 6 1 HEAT-like repeat Cnd3 PF12719.7 CAM41979.1 - 0.025 13.8 0.0 0.07 12.3 0.0 1.7 1 1 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 CAM41979.1 - 0.029 14.6 2.5 69 4.1 0.1 5.5 6 0 0 6 6 6 0 HEAT repeat DUF3137 PF11335.8 CAM41979.1 - 0.17 11.8 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3137) PEP-utilizers_C PF02896.18 CAM41980.2 - 1.5e-90 303.3 0.0 2.6e-90 302.5 0.0 1.3 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.19 CAM41980.2 - 1.4e-75 254.6 0.0 2.4e-73 247.3 0.0 2.1 1 1 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 CAM41980.2 - 4.9e-28 96.7 0.5 1.2e-27 95.4 0.5 1.7 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain Sigma70_r4 PF04545.16 CAM41980.2 - 0.013 15.0 0.0 0.04 13.4 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 DUF3788 PF12663.7 CAM41980.2 - 0.015 15.2 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3788) HTH_AsnC-type PF13404.6 CAM41980.2 - 0.06 13.2 0.1 0.16 11.8 0.1 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain DUF968 PF06147.11 CAM41980.2 - 0.06 13.6 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF968) HTH_24 PF13412.6 CAM41980.2 - 0.098 12.2 0.0 0.26 10.9 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding PEP-utilisers_N PF05524.13 CAM41980.2 - 0.1 12.8 0.2 5.3 7.2 0.1 2.9 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Exo_endo_phos PF03372.23 CAM41981.1 - 0.0018 17.8 0.0 0.005 16.4 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Lactamase_B_2 PF12706.7 CAM41981.1 - 0.07 12.6 0.2 0.12 11.8 0.2 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain SAT PF16073.5 CAM41982.1 - 7.9e-08 32.3 0.2 6.2e-07 29.4 0.0 2.4 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis SecY PF00344.20 CAM41985.1 - 8.3e-63 212.5 9.0 1.1e-62 212.1 9.0 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 CAM41985.1 - 2.4e-13 49.6 0.0 5.7e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 Plug domain of Sec61p TMEM237 PF15383.6 CAM41985.1 - 0.027 13.6 0.2 0.051 12.7 0.2 1.4 1 0 0 1 1 1 0 Transmembrane protein 237 DHHC PF01529.20 CAM41986.1 - 1.1e-26 93.5 12.7 1.1e-26 93.5 12.7 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase DHHC PF01529.20 CAM41987.1 - 7.1e-23 81.2 19.0 7.1e-23 81.2 19.0 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase EcsB PF05975.12 CAM41987.1 - 0.12 11.2 6.7 0.44 9.4 0.8 2.1 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB p450 PF00067.22 CAM41988.1 - 3.4e-66 223.9 0.0 4.1e-66 223.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L28e PF01778.17 CAM41989.1 - 1.3e-16 61.4 0.1 1.3e-16 61.4 0.1 1.4 2 0 0 2 2 2 1 Ribosomal L28e protein family Put_DNA-bind_N PF06971.13 CAM41990.1 - 0.088 12.8 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus Ribosomal_L28e PF01778.17 CAM41991.1 - 7.7e-11 42.8 0.1 7.7e-11 42.8 0.1 1.5 2 0 0 2 2 2 1 Ribosomal L28e protein family WD40 PF00400.32 CAM41992.2 - 1.3e-07 32.2 13.2 0.17 12.8 0.5 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat Sec16_C PF12931.7 CAM41992.2 - 4.3e-07 29.9 0.0 3.3e-06 27.0 0.0 2.2 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 TPR_12 PF13424.6 CAM41992.2 - 0.0065 16.7 1.9 0.31 11.3 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CAM41992.2 - 0.016 15.0 1.1 0.54 10.2 0.9 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 CAM41992.2 - 0.034 14.3 7.2 0.49 10.6 0.8 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 CAM41992.2 - 0.24 11.5 1.6 2 8.6 0.6 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Autoind_bind PF03472.15 CAM41993.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Autoinducer binding domain Solute_trans_a PF03619.16 CAM41994.1 - 1.2e-74 251.2 16.0 1.4e-74 250.9 16.0 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Prok-RING_2 PF14445.6 CAM41994.1 - 0.012 15.7 0.5 0.041 14.0 0.5 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 Skp1 PF01466.19 CAM41995.1 - 1.3e-26 92.4 2.2 2.1e-26 91.7 2.2 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 CAM41995.1 - 2.2e-12 47.0 0.0 1e-11 44.8 0.0 2.1 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain ABC2_membrane_3 PF12698.7 CAM41996.1 - 2.9e-63 214.1 64.5 1.2e-43 149.6 23.3 3.1 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 CAM41996.1 - 1.6e-54 184.1 0.0 4.1e-26 92.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CAM41996.1 - 2.6e-16 60.3 0.6 4.2e-06 26.8 0.0 4.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SRP54 PF00448.22 CAM41996.1 - 0.00023 20.9 0.1 0.68 9.5 0.0 2.3 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain DUF4162 PF13732.6 CAM41996.1 - 0.0011 19.6 0.0 1.1 10.1 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) RsgA_GTPase PF03193.16 CAM41996.1 - 0.0031 17.4 0.1 0.34 10.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase SbcCD_C PF13558.6 CAM41996.1 - 0.0054 16.9 0.1 4 7.7 0.0 3.6 3 1 0 3 3 3 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 CAM41996.1 - 0.0063 16.0 0.0 13 5.2 0.0 3.4 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CAM41996.1 - 0.0083 15.9 0.5 1.9 8.3 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 CAM41996.1 - 0.0086 15.8 0.1 0.43 10.3 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 CAM41996.1 - 0.012 16.1 9.6 0.36 11.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 CAM41996.1 - 0.027 13.8 0.2 25 4.1 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin AAA_15 PF13175.6 CAM41996.1 - 0.047 13.4 0.0 6.1 6.4 0.0 3.4 4 0 0 4 4 4 0 AAA ATPase domain MMR_HSR1 PF01926.23 CAM41996.1 - 0.12 12.5 0.2 18 5.4 0.0 2.9 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA PF00004.29 CAM41996.1 - 0.14 12.6 0.2 5 7.5 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC2_membrane PF01061.24 CAM41996.1 - 0.29 10.5 58.0 0.0069 15.8 15.0 5.5 4 1 1 5 5 5 0 ABC-2 type transporter DUF4407 PF14362.6 CAM41996.1 - 2.3 7.5 5.1 0.38 10.1 1.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) GTP_EFTU PF00009.27 CAM41997.2 - 5.7e-41 140.2 0.0 1.1e-40 139.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CAM41997.2 - 5.3e-29 100.8 0.1 1.9e-28 99.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CAM41997.2 - 0.00016 22.0 0.5 0.0012 19.2 0.3 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CAM41997.2 - 0.0011 19.0 0.0 0.0067 16.5 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 CAM41997.2 - 0.04 13.1 0.0 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit NAM-associated PF14303.6 CAM41997.2 - 0.16 12.7 7.5 0.34 11.6 7.5 1.6 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Mitofilin PF09731.9 CAM41997.2 - 0.22 10.3 8.8 0.33 9.7 8.8 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein TFIIA PF03153.13 CAM41997.2 - 1.2 9.0 8.0 1.7 8.6 8.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hamartin PF04388.12 CAM41997.2 - 8.9 4.8 8.5 11 4.5 8.5 1.1 1 0 0 1 1 1 0 Hamartin protein 60KD_IMP PF02096.20 CAM41998.1 - 1.4e-09 38.1 0.2 2.5e-09 37.3 0.2 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein Ribosomal_S8 PF00410.19 CAM41999.1 - 5.1e-21 74.9 0.0 6.4e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 ABC2_membrane_3 PF12698.7 CAM42000.2 - 8e-60 202.8 47.0 9.1e-39 133.5 17.0 3.0 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 CAM42000.2 - 5.5e-51 172.7 0.0 1.2e-26 93.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CAM42000.2 - 1.4e-15 58.0 0.1 5.2e-05 23.2 0.0 4.2 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CAM42000.2 - 5.9e-05 22.6 0.0 0.86 9.0 0.0 3.7 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CAM42000.2 - 7.4e-05 23.3 1.7 0.1 13.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 CAM42000.2 - 0.00033 20.8 0.0 0.35 11.1 0.0 3.8 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 CAM42000.2 - 0.00037 20.3 0.0 0.067 12.9 0.0 2.7 3 0 0 3 3 3 1 AAA domain SRP54 PF00448.22 CAM42000.2 - 0.00038 20.2 0.5 0.15 11.7 0.0 2.3 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_29 PF13555.6 CAM42000.2 - 0.00095 18.9 0.9 0.54 10.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CAM42000.2 - 0.0015 18.4 0.3 0.06 13.2 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 CAM42000.2 - 0.0028 18.0 0.1 3.3 8.1 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_15 PF13175.6 CAM42000.2 - 0.0058 16.4 0.0 1.3 8.7 0.0 3.4 4 0 0 4 4 4 1 AAA ATPase domain AAA_19 PF13245.6 CAM42000.2 - 0.057 13.8 1.0 4.2 7.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CAM42000.2 - 0.069 13.4 0.1 6.6 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF4162 PF13732.6 CAM42000.2 - 0.093 13.5 0.0 13 6.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) AAA_24 PF13479.6 CAM42000.2 - 0.097 12.4 0.1 9 6.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CAM42000.2 - 0.14 11.7 0.1 3.4 7.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CAM42000.2 - 0.15 11.3 0.1 13 5.0 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin TsaE PF02367.17 CAM42000.2 - 0.15 12.1 0.1 8.7 6.4 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MukB PF04310.12 CAM42000.2 - 0.17 11.6 1.9 3.4 7.4 0.1 2.4 2 0 0 2 2 2 0 MukB N-terminal cobW PF02492.19 CAM42000.2 - 0.18 11.4 1.2 6.8 6.2 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 CAM42000.2 - 0.2 11.8 0.4 9.9 6.3 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC2_membrane_3 PF12698.7 CAM42001.2 - 3.6e-56 190.7 50.2 3.5e-39 134.9 12.0 3.5 4 0 0 4 4 4 2 ABC-2 family transporter protein ABC_tran PF00005.27 CAM42001.2 - 1.3e-50 171.5 0.0 3e-26 92.5 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CAM42001.2 - 4.5e-16 59.5 0.1 2.1e-05 24.5 0.0 4.2 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CAM42001.2 - 6.7e-05 23.5 1.7 0.097 13.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain SRP54 PF00448.22 CAM42001.2 - 0.00032 20.4 0.5 0.14 11.7 0.0 2.3 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_30 PF13604.6 CAM42001.2 - 0.00034 20.4 0.0 0.063 13.0 0.0 2.6 3 0 0 3 3 3 1 AAA domain SMC_N PF02463.19 CAM42001.2 - 0.00056 19.4 0.0 10 5.5 0.0 3.8 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CAM42001.2 - 0.00093 18.9 0.9 0.51 10.1 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.6 CAM42001.2 - 0.0017 18.5 0.0 1.9 8.8 0.0 3.8 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 CAM42001.2 - 0.0018 18.2 0.6 0.057 13.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_15 PF13175.6 CAM42001.2 - 0.0032 17.2 0.0 1.2 8.8 0.0 3.4 4 0 0 4 4 4 1 AAA ATPase domain AAA_16 PF13191.6 CAM42001.2 - 0.0073 16.7 0.0 3.2 8.1 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 CAM42001.2 - 0.048 14.0 1.0 4 7.8 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CAM42001.2 - 0.064 13.5 0.1 6.3 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF4162 PF13732.6 CAM42001.2 - 0.074 13.8 0.0 12 6.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) AAA_24 PF13479.6 CAM42001.2 - 0.088 12.5 0.1 8.3 6.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CAM42001.2 - 0.12 11.9 0.1 3.2 7.3 0.1 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CAM42001.2 - 0.14 11.4 0.1 12 5.1 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin TsaE PF02367.17 CAM42001.2 - 0.15 12.1 0.1 8.4 6.4 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MukB PF04310.12 CAM42001.2 - 0.15 11.8 1.9 3.2 7.5 0.1 2.4 2 0 0 2 2 2 0 MukB N-terminal cobW PF02492.19 CAM42001.2 - 0.16 11.5 1.2 6.5 6.3 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 CAM42001.2 - 0.18 11.9 0.4 9.4 6.4 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC2_membrane_3 PF12698.7 CAM42002.2 - 2.6e-68 230.7 59.8 2.9e-48 164.8 16.0 2.8 3 0 0 3 3 3 2 ABC-2 family transporter protein ABC_tran PF00005.27 CAM42002.2 - 2.5e-51 173.8 0.0 1.2e-25 90.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CAM42002.2 - 3.1e-17 63.3 0.1 3.1e-06 27.2 0.0 4.1 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CAM42002.2 - 7e-06 26.0 0.0 1.6 8.3 0.0 4.1 4 0 0 4 4 4 1 AAA ATPase domain SMC_N PF02463.19 CAM42002.2 - 8.6e-06 25.3 0.1 0.57 9.6 0.0 3.3 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CAM42002.2 - 5e-05 23.9 0.5 0.16 12.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 CAM42002.2 - 0.00038 20.4 0.0 0.062 13.2 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase SbcCD_C PF13558.6 CAM42002.2 - 0.00094 19.4 0.0 0.57 10.4 0.0 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 CAM42002.2 - 0.0017 18.1 0.1 0.61 9.9 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain SRP54 PF00448.22 CAM42002.2 - 0.0017 18.0 0.2 0.48 10.0 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 CAM42002.2 - 0.0019 17.5 0.0 13 5.0 0.0 3.3 3 0 0 3 3 3 0 Zeta toxin DUF4162 PF13732.6 CAM42002.2 - 0.0022 18.6 0.0 4.2 8.2 0.0 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4162) AAA_30 PF13604.6 CAM42002.2 - 0.014 15.2 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CAM42002.2 - 0.037 14.4 0.0 2 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain Arf PF00025.21 CAM42002.2 - 0.076 12.5 0.1 4.6 6.7 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_22 PF13401.6 CAM42002.2 - 0.12 12.7 0.0 2.9 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CAM42002.2 - 0.12 12.8 0.1 3.5 8.0 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 CAM42002.2 - 0.15 11.6 0.5 4.9 6.7 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 CAM42002.2 - 0.15 12.3 0.3 8.5 6.6 0.1 2.9 3 0 0 3 3 3 0 AAA domain ABC2_membrane PF01061.24 CAM42002.2 - 0.17 11.2 53.4 0.0061 16.0 13.0 4.0 4 0 0 4 4 4 0 ABC-2 type transporter AAA_19 PF13245.6 CAM42002.2 - 0.18 12.1 0.2 16 5.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CAM42002.2 - 0.19 11.8 0.1 15 5.7 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase LapA_dom PF06305.11 CAM42002.2 - 3.3 7.6 6.3 0.38 10.6 0.4 2.6 2 0 0 2 2 1 0 Lipopolysaccharide assembly protein A domain TatD_DNase PF01026.21 CAM42003.1 - 2e-43 148.6 0.0 2.7e-43 148.2 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 CAM42003.1 - 0.0051 16.6 0.0 0.48 10.2 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase ABC2_membrane_3 PF12698.7 CAM42004.1 - 3.6e-69 233.5 53.0 1.2e-46 159.4 19.3 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 CAM42004.1 - 1.3e-49 168.2 0.0 2.2e-24 86.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CAM42004.1 - 2.7e-16 60.3 1.3 1.8e-08 34.6 0.0 4.0 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CAM42004.1 - 3.3e-08 33.2 0.0 0.053 13.0 0.0 3.5 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 CAM42004.1 - 5.1e-05 23.2 0.0 1.3 8.7 0.0 3.9 4 0 0 4 4 4 2 AAA ATPase domain RsgA_GTPase PF03193.16 CAM42004.1 - 6e-05 23.0 0.1 0.048 13.6 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 CAM42004.1 - 0.00013 22.6 0.3 0.4 11.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 CAM42004.1 - 0.00014 22.0 0.0 0.53 10.5 0.0 4.0 3 2 0 3 3 3 1 Putative exonuclease SbcCD, C subunit SRP54 PF00448.22 CAM42004.1 - 0.00058 19.5 0.3 0.43 10.2 0.0 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_29 PF13555.6 CAM42004.1 - 0.0013 18.4 0.1 0.3 10.9 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 CAM42004.1 - 0.0018 18.0 0.0 0.21 11.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain KdpD PF02702.17 CAM42004.1 - 0.0068 15.9 0.0 0.016 14.6 0.0 1.6 1 0 0 1 1 1 1 Osmosensitive K+ channel His kinase sensor domain Zeta_toxin PF06414.12 CAM42004.1 - 0.015 14.6 0.0 17 4.6 0.0 3.4 3 1 0 4 4 4 0 Zeta toxin AAA PF00004.29 CAM42004.1 - 0.061 13.8 0.0 2.3 8.7 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Arf PF00025.21 CAM42004.1 - 0.081 12.4 0.1 3.9 6.9 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CAM42004.1 - 0.09 12.9 0.1 11 6.1 0.0 3.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 CAM42004.1 - 0.13 12.7 0.2 25 5.3 0.0 2.9 2 0 0 2 2 2 0 RNA helicase MukB PF04310.12 CAM42004.1 - 1.8 8.3 4.6 18 5.0 0.0 2.8 3 0 0 3 3 3 0 MukB N-terminal HEAT PF02985.22 CAM42006.1 - 0.00082 19.4 2.1 4.5 7.8 0.0 4.5 5 0 0 5 5 5 2 HEAT repeat Adaptin_N PF01602.20 CAM42006.1 - 0.021 13.4 2.8 0.42 9.1 0.1 2.5 2 1 1 3 3 3 0 Adaptin N terminal region HEAT_2 PF13646.6 CAM42006.1 - 2.4 8.6 10.9 0.31 11.5 0.3 3.9 2 2 2 4 4 4 0 HEAT repeats Ycf66_N PF07444.11 CAM42007.1 - 0.017 15.2 1.0 3.3 7.9 0.1 3.6 3 0 0 3 3 3 0 Ycf66 protein N-terminus DUF5546 PF17700.1 CAM42007.1 - 0.065 13.6 0.8 0.065 13.6 0.8 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5546) Hydrolase_like PF13242.6 CAM42007.1 - 0.081 13.0 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like DUF3302 PF11742.8 CAM42007.1 - 0.32 11.1 3.9 0.36 11.0 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3302) PapD-like PF14874.6 CAM42008.1 - 6.9e-47 157.8 0.6 1.8e-46 156.5 0.6 1.8 1 0 0 1 1 1 1 Flagellar-associated PapD-like Nodulin-like PF06813.13 CAM42009.1 - 1.1e-14 54.5 13.7 1.1e-14 54.5 13.7 3.0 2 2 1 3 3 3 1 Nodulin-like MFS_1 PF07690.16 CAM42009.1 - 1.7e-08 33.8 43.7 1.2e-06 27.7 10.5 3.3 2 1 0 2 2 2 2 Major Facilitator Superfamily BLOC1_2 PF10046.9 CAM42011.1 - 0.00017 21.8 5.0 0.0017 18.6 5.0 2.0 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 THOC7 PF05615.13 CAM42011.1 - 0.00052 20.3 0.2 0.00065 20.0 0.2 1.3 1 0 0 1 1 1 1 Tho complex subunit 7 Uso1_p115_C PF04871.13 CAM42011.1 - 0.0033 17.8 7.6 0.0046 17.3 7.6 1.1 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region HAUS-augmin3 PF14932.6 CAM42011.1 - 0.0036 16.9 1.4 0.0053 16.4 1.4 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 KxDL PF10241.9 CAM42011.1 - 0.0099 16.1 2.0 0.015 15.6 1.2 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein Spc7 PF08317.11 CAM42011.1 - 0.02 13.8 1.8 0.028 13.3 1.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.15 CAM42011.1 - 0.025 14.3 1.3 0.025 14.3 1.3 2.0 1 1 1 2 2 2 0 Septum formation initiator DUF3450 PF11932.8 CAM42011.1 - 0.047 13.0 4.6 0.019 14.3 2.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF4175 PF13779.6 CAM42011.1 - 0.055 11.4 3.3 0.06 11.2 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4472 PF14739.6 CAM42011.1 - 0.27 12.0 4.6 0.41 11.4 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) YabA PF06156.13 CAM42011.1 - 0.52 11.0 3.6 1.2 9.8 3.6 1.6 1 1 0 1 1 1 0 Initiation control protein YabA CENP-H PF05837.12 CAM42011.1 - 0.52 10.7 5.8 0.62 10.5 5.1 1.4 1 1 0 1 1 1 0 Centromere protein H (CENP-H) ZapB PF06005.12 CAM42011.1 - 0.91 10.0 10.0 2.2 8.8 9.9 1.8 1 1 0 1 1 1 0 Cell division protein ZapB DUF4140 PF13600.6 CAM42011.1 - 1 9.8 7.5 18 5.9 7.7 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Ribosomal_L4 PF00573.22 CAM42012.1 - 4e-10 39.7 0.0 1.2e-09 38.1 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein L4/L1 family STIMATE PF12400.8 CAM42013.1 - 0.0011 19.5 4.1 0.0011 19.5 4.1 1.7 2 0 0 2 2 2 1 STIMATE family TruD PF01142.18 CAM42014.1 - 0.014 14.3 0.0 0.023 13.5 0.0 1.3 1 0 0 1 1 1 0 tRNA pseudouridine synthase D (TruD) SH3_9 PF14604.6 CAM42015.2 - 1.5e-10 40.7 0.0 9.7e-10 38.2 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 CAM42015.2 - 5.7e-10 38.7 0.0 1.1e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CAM42015.2 - 2.6e-09 36.6 0.0 1.1e-07 31.4 0.0 2.5 2 0 0 2 2 2 1 Variant SH3 domain RVT_1 PF00078.27 CAM42016.1 - 0.0021 17.6 0.0 0.0049 16.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_integrase PF00589.22 CAM42017.2 - 1.5e-06 28.1 0.0 9.5e-06 25.5 0.0 2.4 2 0 0 2 2 2 1 Phage integrase family RVT_1 PF00078.27 CAM42017.2 - 0.0025 17.4 0.0 0.0071 15.9 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A17 PF05380.13 CAM42017.2 - 0.0043 17.1 0.1 0.056 13.4 0.0 2.5 1 1 1 2 2 2 1 Pao retrotransposon peptidase CENP-T_C PF15511.6 CAM42018.1 - 1e-05 25.6 0.1 1.7e-05 24.9 0.0 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CAM42018.1 - 0.00056 20.0 0.1 0.00088 19.4 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 CAM42018.1 - 0.00058 20.1 0.4 0.00081 19.6 0.0 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 CAM42018.1 - 0.0025 17.8 0.0 0.0029 17.6 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 CAM42018.1 - 0.0042 17.4 1.7 0.0082 16.5 1.7 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CAM42018.1 - 0.063 13.3 0.0 0.083 13.0 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit GDA1_CD39 PF01150.17 CAM42020.1 - 2e-80 270.5 0.0 2.5e-80 270.2 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 CAM42020.1 - 0.00019 21.0 0.0 0.00028 20.4 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Lysine_decarbox PF03641.14 CAM42021.1 - 4.2e-23 81.9 0.0 8.2e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 CAM42021.1 - 3.6e-08 33.1 0.0 7.6e-08 32.1 0.0 1.5 1 1 0 1 1 1 1 SLOG cluster4 family NAD_binding_1 PF00175.21 CAM42022.1 - 3.6e-28 98.4 0.0 5.9e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CAM42022.1 - 4.4e-25 87.9 0.0 6.6e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CAM42022.1 - 3.2e-06 27.3 0.0 0.00025 21.2 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain MIF4G PF02854.19 CAM42023.1 - 3.2e-25 89.0 1.5 5.3e-25 88.3 1.5 1.4 1 0 0 1 1 1 1 MIF4G domain CRM1_C PF08767.11 CAM42023.1 - 0.00025 20.3 0.1 0.00093 18.4 0.0 2.0 2 0 0 2 2 2 1 CRM1 C terminal IMS PF00817.20 CAM42023.1 - 0.057 13.4 0.1 1.9 8.5 0.0 2.6 3 0 0 3 3 3 0 impB/mucB/samB family AAA_2 PF07724.14 CAM42026.1 - 1.5e-39 135.9 1.9 4.1e-31 108.4 0.4 2.8 1 1 1 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 CAM42026.1 - 1.5e-13 51.3 0.1 6.6e-06 26.6 0.0 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CAM42026.1 - 7.6e-09 35.7 0.4 2.1e-05 24.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CAM42026.1 - 6.7e-06 26.4 0.0 0.00033 21.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain MCM PF00493.23 CAM42026.1 - 1.3e-05 24.4 0.2 0.0015 17.7 0.0 2.4 2 0 0 2 2 2 1 MCM P-loop domain TniB PF05621.11 CAM42026.1 - 4.5e-05 22.9 0.4 0.0043 16.5 0.0 2.5 2 1 0 2 2 2 1 Bacterial TniB protein AAA_18 PF13238.6 CAM42026.1 - 9.5e-05 23.0 0.2 0.0003 21.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 CAM42026.1 - 0.00011 21.7 0.1 0.0023 17.4 0.0 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 CAM42026.1 - 0.00025 21.5 0.3 0.00075 19.9 0.3 1.7 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 CAM42026.1 - 0.00065 19.0 0.8 0.0011 18.3 0.0 1.7 2 1 0 2 2 2 1 TIP49 P-loop domain NTPase_1 PF03266.15 CAM42026.1 - 0.00088 19.2 1.0 0.57 10.1 0.0 2.7 2 0 0 2 2 2 2 NTPase RuvB_N PF05496.12 CAM42026.1 - 0.0018 18.0 0.1 0.015 15.1 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DEAD PF00270.29 CAM42026.1 - 0.0019 18.0 0.1 1.2 8.9 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_14 PF13173.6 CAM42026.1 - 0.0065 16.5 0.1 3.3 7.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CAM42026.1 - 0.0079 15.9 0.6 0.36 10.5 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CAM42026.1 - 0.0092 16.2 0.0 0.028 14.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain TsaE PF02367.17 CAM42026.1 - 0.013 15.5 0.0 0.039 13.9 0.0 1.8 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 CAM42026.1 - 0.02 14.6 0.0 0.065 12.9 0.0 1.8 2 0 0 2 2 1 0 Sigma-54 interaction domain AAA_28 PF13521.6 CAM42026.1 - 0.02 15.1 0.1 0.15 12.3 0.0 2.4 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 CAM42026.1 - 0.02 13.9 0.0 0.056 12.5 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 CAM42026.1 - 0.027 13.7 0.0 0.06 12.6 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin CPT PF07931.12 CAM42026.1 - 0.035 13.9 0.3 0.27 11.0 0.0 2.5 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.27 CAM42026.1 - 0.04 14.4 0.1 0.095 13.2 0.1 1.6 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 CAM42026.1 - 0.045 13.7 0.0 0.098 12.6 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 CAM42026.1 - 0.047 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 CAM42026.1 - 0.048 13.2 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 CAM42026.1 - 0.052 13.5 0.0 3.3 7.6 0.0 2.7 2 1 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 CAM42026.1 - 0.058 13.7 1.6 0.11 12.8 0.8 1.9 2 1 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 CAM42026.1 - 0.15 12.4 0.0 0.95 9.9 0.0 2.3 2 1 0 2 2 2 0 RNA helicase AMP-binding_C_2 PF14535.6 CAM42026.1 - 0.17 12.2 2.5 10 6.5 0.3 3.5 2 1 1 3 3 3 0 AMP-binding enzyme C-terminal domain AAA_17 PF13207.6 CAM42026.1 - 3.2 8.2 6.2 4.5 7.7 0.2 3.7 3 1 1 4 4 4 0 AAA domain FMO-like PF00743.19 CAM42027.1 - 1.7e-26 92.8 0.1 4.6e-22 78.1 0.2 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 CAM42027.1 - 7.1e-14 51.7 0.0 3.9e-13 49.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CAM42027.1 - 4.1e-09 36.1 1.4 1.5e-05 24.4 0.2 3.2 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CAM42027.1 - 9.3e-08 31.6 1.2 4.7e-06 26.0 0.4 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 CAM42027.1 - 3.3e-06 27.2 0.0 1.7e-05 25.0 0.0 2.4 2 1 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CAM42027.1 - 0.00046 20.7 0.1 0.59 10.7 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CAM42027.1 - 0.011 14.5 0.1 0.016 13.9 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein IlvN PF07991.12 CAM42027.1 - 0.021 14.4 0.0 3.4 7.2 0.0 2.5 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 CAM42027.1 - 0.029 13.7 0.1 7.3 5.8 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 CAM42027.1 - 0.042 13.1 0.1 0.098 11.9 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 CAM42027.1 - 0.058 13.4 2.0 0.35 10.8 0.3 2.9 2 1 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 CAM42027.1 - 0.063 13.7 0.4 4.3 7.8 0.0 3.1 3 0 0 3 3 3 0 Putative NAD(P)-binding DUF1490 PF07371.12 CAM42027.1 - 0.082 13.0 0.3 0.35 11.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1490) GIDA PF01134.22 CAM42027.1 - 0.086 11.9 0.8 1.7 7.6 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Mito_carr PF00153.27 CAM42029.1 - 1.6e-44 149.7 0.6 6.1e-16 58.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CbiM PF01891.16 CAM42029.1 - 0.002 18.0 1.8 0.037 13.9 0.0 2.4 2 1 1 3 3 3 2 Cobalt uptake substrate-specific transmembrane region DEAD PF00270.29 CAM42030.1 - 1.2e-41 142.4 0.1 2.4e-41 141.4 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAM42030.1 - 1.6e-25 89.6 5.6 1.8e-25 89.4 0.1 3.4 3 1 1 4 4 4 1 Helicase conserved C-terminal domain zf-CCCH PF00642.24 CAM42031.1 - 2.3e-07 30.5 5.3 2.3e-07 30.5 5.3 2.3 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) oligo_HPY PF08352.12 CAM42031.1 - 0.013 16.0 3.7 0.68 10.5 0.6 2.5 2 0 0 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region Torus PF16131.5 CAM42031.1 - 0.021 15.5 5.4 1.8 9.3 0.6 2.2 2 0 0 2 2 2 0 Torus domain zf-CCCH_4 PF18044.1 CAM42031.1 - 2.7 7.9 11.1 0.13 12.0 4.2 2.4 2 0 0 2 2 2 0 CCCH-type zinc finger zf-CCCH PF00642.24 CAM42032.1 - 4.8e-07 29.5 4.0 8e-07 28.8 4.0 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CAM42032.1 - 5.2e-05 22.9 2.3 8.8e-05 22.2 2.3 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CAM42032.1 - 0.032 14.3 2.6 0.058 13.5 2.6 1.5 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH_2 PF14608.6 CAM42032.1 - 0.062 13.8 2.2 0.12 12.9 2.2 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger PP2C PF00481.21 CAM42033.1 - 7.3e-67 225.7 0.5 7.3e-67 225.7 0.5 1.6 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 CAM42033.1 - 4.4e-05 23.2 0.8 0.00089 19.0 0.1 2.4 2 1 0 2 2 2 1 Protein phosphatase 2C DUF3276 PF11680.8 CAM42033.1 - 0.0064 16.6 3.3 0.012 15.7 2.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3276) Gastrin PF00918.17 CAM42033.1 - 0.04 14.9 0.6 0.099 13.6 0.6 1.6 1 0 0 1 1 1 0 Gastrin/cholecystokinin family LPD13 PF18825.1 CAM42033.1 - 0.045 13.5 2.9 0.11 12.3 2.7 1.7 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 13 Pkinase PF00069.25 CAM42034.1 - 7.3e-43 146.8 0.0 1.2e-42 146.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM42034.1 - 8.2e-15 54.8 0.0 1.4e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CAM42034.1 - 1.5e-05 25.0 0.4 0.0027 17.7 0.0 2.6 2 1 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 CAM42034.1 - 0.0061 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase LRRCT PF01463.24 CAM42035.1 - 0.028 14.9 1.5 1.2 9.8 0.0 3.5 2 0 0 2 2 2 0 Leucine rich repeat C-terminal domain TolA_bind_tri PF16331.5 CAM42035.1 - 0.24 11.5 2.1 22 5.2 0.0 3.3 3 0 0 3 3 3 0 TolA binding protein trimerisation FliJ PF02050.16 CAM42035.1 - 0.73 10.1 7.0 3.3 8.0 0.1 2.7 3 0 0 3 3 3 0 Flagellar FliJ protein HIP1_clath_bdg PF16515.5 CAM42035.1 - 3.2 8.4 8.3 39 4.9 0.3 3.5 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Cyt-b5 PF00173.28 CAM42036.1 - 1.7e-07 31.2 0.0 2.5e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ribosomal_L13 PF00572.18 CAM42038.1 - 2.2e-06 27.9 3.8 2.8e-05 24.4 0.9 2.6 2 1 0 2 2 2 1 Ribosomal protein L13 DUF4455 PF14643.6 CAM42038.1 - 0.011 14.4 1.3 0.016 13.9 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) CAP160 PF07918.11 CAM42039.2 - 1.8 8.4 4.4 4.6 7.1 4.4 1.6 1 0 0 1 1 1 0 CAP160 repeat Metallophos PF00149.28 CAM42040.1 - 5.4e-32 112.0 0.0 7.2e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CAM42040.1 - 0.01 16.3 0.8 0.034 14.6 0.3 2.1 2 0 0 2 2 2 0 Serine-threonine protein phosphatase N-terminal domain WD40 PF00400.32 CAM42042.1 - 3.9e-10 40.1 1.0 0.0032 18.2 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat tRNA-synt_2 PF00152.20 CAM42043.1 - 3.6e-76 256.2 0.1 5.8e-76 255.6 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CAM42043.1 - 8.3e-12 44.9 0.1 1.7e-11 44.0 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CAM42043.1 - 5.2e-07 29.4 0.0 0.0053 16.3 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) YabA PF06156.13 CAM42043.1 - 0.1 13.3 0.6 0.18 12.4 0.0 1.7 2 0 0 2 2 2 0 Initiation control protein YabA DUF4580 PF15162.6 CAM42043.1 - 0.18 11.4 0.1 0.36 10.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4580) Cellulose_synt PF03552.14 CAM42046.1 - 0.032 12.7 0.6 0.044 12.3 0.6 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF1676 PF07898.13 CAM42046.1 - 4.4 7.3 6.0 9.4 6.2 6.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) RPA_C PF08784.11 CAM42047.1 - 1.6e-12 48.0 1.1 3.3e-12 47.0 1.1 1.5 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 CAM42047.1 - 1e-06 28.6 0.0 1.9e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain PPR_2 PF13041.6 CAM42048.1 - 5e-07 29.8 0.9 0.03 14.5 0.0 2.3 2 0 0 2 2 2 2 PPR repeat family PPR_long PF17177.4 CAM42048.1 - 0.0015 18.0 0.0 0.24 10.7 0.0 2.1 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 CAM42048.1 - 0.011 16.2 0.0 0.017 15.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) FERM_f0 PF16511.5 CAM42048.1 - 0.017 15.4 0.0 0.053 13.8 0.0 1.7 2 0 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM PPR_3 PF13812.6 CAM42048.1 - 0.02 14.9 0.1 0.61 10.2 0.0 2.2 2 0 0 2 2 2 0 Pentatricopeptide repeat domain PPR_2 PF13041.6 CAM42049.1 - 5e-07 29.8 0.9 0.03 14.5 0.0 2.3 2 0 0 2 2 2 2 PPR repeat family PPR_long PF17177.4 CAM42049.1 - 0.0015 18.0 0.0 0.24 10.7 0.0 2.1 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 CAM42049.1 - 0.011 16.2 0.0 0.017 15.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) FERM_f0 PF16511.5 CAM42049.1 - 0.017 15.4 0.0 0.053 13.8 0.0 1.7 2 0 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM PPR_3 PF13812.6 CAM42049.1 - 0.02 14.9 0.1 0.61 10.2 0.0 2.2 2 0 0 2 2 2 0 Pentatricopeptide repeat domain Ecotin PF03974.13 CAM42051.1 - 3.2e-39 133.7 0.0 3.7e-39 133.5 0.0 1.0 1 0 0 1 1 1 1 Ecotin Uma2 PF05685.12 CAM42051.1 - 0.099 12.2 0.0 2.7 7.5 0.0 2.0 1 1 1 2 2 2 0 Putative restriction endonuclease Lant_dehydr_C PF14028.6 CAM42052.1 - 0.1 12.1 0.0 0.27 10.7 0.0 1.8 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term Abhydrolase_3 PF07859.13 CAM42053.1 - 1.3e-12 48.0 0.1 6.1e-12 45.9 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 CAM42053.1 - 1.3e-09 37.5 0.1 2.3e-08 33.4 0.0 2.2 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_6 PF12697.7 CAM42053.1 - 2.9e-06 28.0 0.0 7.6e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CAM42053.1 - 5.6e-05 22.7 0.1 0.036 13.5 0.1 2.9 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 CAM42053.1 - 0.009 15.7 0.1 0.028 14.1 0.1 1.8 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF4566 PF15130.6 CAM42053.1 - 0.057 12.8 0.0 0.15 11.5 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4566) Abhydrolase_3 PF07859.13 CAM42054.1 - 5.2e-11 42.8 0.1 9.8e-11 41.9 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 CAM42054.1 - 6.2e-09 35.2 0.0 1.1e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 CAM42054.1 - 1.3e-05 24.8 0.1 0.018 14.5 0.1 2.7 2 1 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 CAM42054.1 - 0.00049 19.1 0.0 0.00082 18.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 CAM42054.1 - 0.015 15.0 0.1 0.031 13.9 0.1 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CAM42054.1 - 0.065 12.5 0.0 0.23 10.7 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 PseudoU_synth_2 PF00849.22 CAM42057.2 - 5.3e-17 62.4 2.2 1.3e-07 31.9 0.4 3.5 3 1 0 3 3 3 3 RNA pseudouridylate synthase Asparaginase PF00710.20 CAM42058.1 - 3.9e-54 183.1 0.0 1.2e-53 181.5 0.0 1.7 2 0 0 2 2 2 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 CAM42058.1 - 1.8e-20 73.2 0.1 2.9e-20 72.6 0.1 1.3 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain DUF3648 PF12364.8 CAM42059.1 - 0.006 16.8 0.3 0.019 15.2 0.3 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3648) PPR_2 PF13041.6 CAM42060.1 - 0.044 14.0 0.0 0.92 9.8 0.0 2.5 1 1 1 2 2 2 0 PPR repeat family DUF3322 PF11795.8 CAM42060.1 - 0.97 9.4 9.3 7.3 6.6 0.5 3.9 4 1 0 4 4 4 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Peptidase_M50B PF13398.6 CAM42061.1 - 0.038 13.6 0.1 0.046 13.4 0.1 1.1 1 0 0 1 1 1 0 Peptidase M50B-like OB_MalK PF17912.1 CAM42063.1 - 3e-05 24.8 5.7 82 4.2 0.0 8.3 8 0 0 8 8 8 2 MalK OB fold domain CagY_M PF07337.11 CAM42063.1 - 0.063 12.9 42.5 2.3e+02 1.5 0.1 16.0 17 0 0 17 17 17 0 DC-EC Repeat AAA PF00004.29 CAM42067.1 - 1.3e-38 132.4 0.0 2.3e-38 131.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAM42067.1 - 1.8e-11 43.6 0.1 4.4e-11 42.4 0.1 1.7 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 CAM42067.1 - 1.4e-05 25.1 0.1 0.00011 22.2 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CAM42067.1 - 3.4e-05 23.7 0.0 7.4e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CAM42067.1 - 0.0003 21.2 2.2 0.021 15.2 0.0 3.6 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 CAM42067.1 - 0.00048 20.4 0.1 0.0077 16.5 0.1 2.6 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 CAM42067.1 - 0.0032 16.7 0.0 0.0053 16.0 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 CAM42067.1 - 0.0034 17.5 0.0 0.0058 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 CAM42067.1 - 0.0046 16.4 0.1 0.012 15.0 0.1 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CAM42067.1 - 0.0059 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 CAM42067.1 - 0.011 15.4 0.2 0.58 9.7 0.0 2.7 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 CAM42067.1 - 0.022 15.3 0.0 0.05 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 CAM42067.1 - 0.037 13.2 0.0 0.075 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 CAM42067.1 - 0.055 13.6 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CAM42067.1 - 0.084 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CAM42067.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 CAM42067.1 - 0.12 11.4 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 CAM42067.1 - 0.15 12.5 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase TniB PF05621.11 CAM42067.1 - 0.21 11.0 0.0 2.7 7.4 0.0 2.4 3 0 0 3 3 3 0 Bacterial TniB protein Kelch_4 PF13418.6 CAM42068.1 - 2.3e-20 72.4 3.0 2.4e-05 24.3 0.0 6.7 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 CAM42068.1 - 4.2e-18 64.9 1.6 0.0017 18.3 0.0 5.8 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 CAM42068.1 - 6e-15 54.9 2.1 5.5e-07 29.7 0.1 3.9 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 CAM42068.1 - 5.2e-14 52.1 4.3 0.00058 20.1 0.1 6.5 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 CAM42068.1 - 5.4e-13 48.4 3.4 0.00023 21.0 0.0 4.1 3 0 0 3 3 3 3 Kelch motif Kelch_1 PF01344.25 CAM42068.1 - 2.1e-08 33.6 7.8 0.015 14.9 0.1 4.2 4 0 0 4 4 4 3 Kelch motif Ecotin PF03974.13 CAM42071.1 - 1.1e-41 141.6 0.0 1.3e-41 141.4 0.0 1.0 1 0 0 1 1 1 1 Ecotin Ecotin PF03974.13 CAM42072.1 - 6.4e-36 123.0 0.0 9.5e-36 122.5 0.0 1.3 1 0 0 1 1 1 1 Ecotin Fungal_TACC PF12709.7 CAM42074.1 - 0.1 13.1 0.1 0.1 13.1 0.1 6.2 7 1 2 9 9 9 0 Fungal Transforming acidic coiled-coil (TACC) proteins WXG100 PF06013.12 CAM42074.1 - 1.4 9.2 15.7 1.2 9.4 0.8 5.0 3 1 0 3 3 3 0 Proteins of 100 residues with WXG DUF3587 PF12132.8 CAM42075.2 - 0.069 12.6 0.4 0.12 11.8 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3587) ATG16 PF08614.11 CAM42076.1 - 0.0017 18.6 11.7 0.0017 18.6 11.7 3.8 3 2 0 4 4 4 1 Autophagy protein 16 (ATG16) DUF5094 PF17015.5 CAM42076.1 - 0.0079 16.3 0.5 41 4.2 4.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5094) RPT PF13446.6 CAM42076.1 - 0.012 15.5 0.4 0.22 11.5 0.1 3.0 3 0 0 3 3 3 0 A repeated domain in UCH-protein TcdB_N PF12918.7 CAM42076.1 - 0.042 14.2 0.0 0.094 13.0 0.0 1.6 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain Mito_fiss_reg PF05308.11 CAM42076.1 - 0.073 13.1 5.7 0.17 11.9 5.7 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator Fmp27_WPPW PF10359.9 CAM42076.1 - 0.11 11.4 5.5 0.22 10.3 5.5 1.5 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain NBP1 PF08537.10 CAM42076.1 - 0.19 11.1 0.0 0.19 11.1 0.0 2.6 3 0 0 3 3 3 0 Fungal Nap binding protein NBP1 Fez1 PF06818.15 CAM42076.1 - 0.29 11.5 20.4 0.4 11.1 7.5 3.9 3 1 0 3 3 3 0 Fez1 HMMR_N PF15905.5 CAM42076.1 - 0.53 9.7 15.6 0.06 12.8 6.1 2.5 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal ERM PF00769.19 CAM42076.1 - 0.8 9.5 18.5 4 7.2 0.8 2.8 2 0 0 2 2 2 0 Ezrin/radixin/moesin family V_ATPase_I PF01496.19 CAM42076.1 - 1.8 6.4 4.8 6.3 4.6 4.4 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 CAM42076.1 - 2.1 8.4 9.7 0.68 10.0 1.8 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Lebercilin PF15619.6 CAM42076.1 - 3.2 7.4 26.8 3.5 7.2 8.6 4.5 4 1 1 5 5 5 0 Ciliary protein causing Leber congenital amaurosis disease DUF4618 PF15397.6 CAM42076.1 - 3.4 7.0 12.2 0.35 10.2 4.5 2.9 2 1 0 3 3 3 0 Domain of unknown function (DUF4618) SPC22 PF04573.12 CAM42078.1 - 1.7e-17 63.4 0.3 3.6e-10 39.6 0.0 3.1 3 0 0 3 3 3 3 Signal peptidase subunit DUF3138 PF11336.8 CAM42078.1 - 0.32 9.6 2.3 0.43 9.1 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF2830 PF11125.8 CAM42078.1 - 1.3 9.0 0.0 1.3 9.0 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2830) FAM183 PF14886.6 CAM42079.1 - 0.013 16.2 0.5 0.039 14.7 0.5 2.1 1 1 0 1 1 1 0 FAM183A and FAM183B related DUF4429 PF14472.6 CAM42079.1 - 0.034 14.7 0.4 2.2 8.9 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4429) DUF2046 PF09755.9 CAM42080.1 - 0.14 11.4 4.3 0.057 12.6 1.4 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) CRAL_TRIO PF00650.20 CAM42082.1 - 4.2e-18 65.6 0.0 4.8e-15 55.6 0.0 2.9 2 1 0 2 2 2 2 CRAL/TRIO domain ESR1_C PF12743.7 CAM42083.1 - 0.014 15.2 0.6 0.014 15.2 0.6 2.4 2 0 0 2 2 2 0 Oestrogen-type nuclear receptor final C-terminal IATP PF04568.12 CAM42083.1 - 0.021 15.2 0.7 0.058 13.8 0.7 1.7 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP DUF842 PF05811.13 CAM42084.2 - 8.4 6.1 12.4 0.34 10.6 5.5 2.0 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) Ipi1_N PF12333.8 CAM42085.1 - 0.0001 22.8 3.4 0.0043 17.6 0.1 3.7 4 0 0 4 4 4 2 Rix1 complex component involved in 60S ribosome maturation Cmc1 PF08583.10 CAM42086.1 - 0.00032 20.6 1.4 0.00032 20.6 1.4 2.2 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like IucA_IucC PF04183.12 CAM42086.1 - 0.13 11.8 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 IucA / IucC family UPF0203 PF05254.12 CAM42086.1 - 0.41 10.9 6.9 0.095 13.0 1.4 2.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0203) Sec5 PF15469.6 CAM42086.1 - 0.56 10.0 5.0 3.6 7.4 0.4 2.6 2 1 1 3 3 3 0 Exocyst complex component Sec5 tRNA_SAD PF07973.14 CAM42087.1 - 0.00027 20.9 0.2 0.0026 17.8 0.1 2.3 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 CAM42087.1 - 0.012 14.1 0.0 0.016 13.7 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class II (A) NMT_C PF02799.15 CAM42087.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain DUF1659 PF07872.11 CAM42088.1 - 0.021 14.5 0.3 0.13 11.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1659) DUF4050 PF13259.6 CAM42088.1 - 1.4 9.2 4.8 8 6.7 0.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4050) TPR_10 PF13374.6 CAM42089.1 - 0.072 13.0 0.1 0.54 10.2 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Pex16 PF08610.10 CAM42091.1 - 1.9e-14 53.6 0.0 8.2e-12 44.9 0.0 2.4 2 0 0 2 2 2 2 Peroxisomal membrane protein (Pex16) Sulfotransfer_4 PF17784.1 CAM42092.1 - 0.24 11.2 3.0 1.3 8.8 0.1 3.1 2 0 0 2 2 2 0 Sulfotransferase domain FAM195 PF14799.6 CAM42092.1 - 0.41 11.0 1.7 5 7.5 0.1 3.1 2 0 0 2 2 2 0 FAM195 family Pkinase PF00069.25 CAM42096.1 - 1.3e-24 87.0 0.0 1.8e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM42096.1 - 6.8e-11 41.9 0.0 1.1e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM42096.1 - 0.0041 16.5 0.0 0.011 15.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like DUF2871 PF11070.8 CAM42097.1 - 8.8e-42 142.6 11.0 1e-41 142.4 11.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2871) TrbC PF04956.13 CAM42097.1 - 0.037 14.3 2.7 0.12 12.6 2.7 1.8 1 1 0 1 1 1 0 TrbC/VIRB2 family Tetraspanin PF00335.20 CAM42097.1 - 0.058 13.1 2.8 0.069 12.8 2.8 1.2 1 0 0 1 1 1 0 Tetraspanin family ABC_tran PF00005.27 CAM42099.2 - 2.5e-55 186.8 0.0 1.4e-28 100.1 0.0 3.4 3 0 0 3 3 3 2 ABC transporter ABC2_membrane_3 PF12698.7 CAM42099.2 - 2.7e-47 161.6 55.7 4.3e-35 121.4 22.0 2.9 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 CAM42099.2 - 2.3e-24 86.8 0.3 4e-09 36.7 0.0 4.4 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CAM42099.2 - 7.8e-08 32.0 0.1 0.83 9.1 0.0 4.1 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain DUF4162 PF13732.6 CAM42099.2 - 5e-07 30.4 0.0 0.0022 18.7 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4162) AAA_29 PF13555.6 CAM42099.2 - 1.7e-05 24.4 0.7 0.0056 16.4 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 CAM42099.2 - 0.00019 22.0 0.4 0.094 13.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 CAM42099.2 - 0.00065 19.6 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 CAM42099.2 - 0.0014 18.4 0.0 0.78 9.4 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.6 CAM42099.2 - 0.034 13.8 0.0 0.64 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CAM42099.2 - 0.036 14.5 0.0 1.1 9.6 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 CAM42099.2 - 0.066 13.5 0.0 1.4 9.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 CAM42099.2 - 0.085 12.1 0.0 6.4 6.0 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin Mg_chelatase PF01078.21 CAM42099.2 - 0.088 12.2 0.2 2.2 7.6 0.0 3.2 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI ABC2_membrane_2 PF12679.7 CAM42099.2 - 1.4 8.1 31.2 0.046 13.0 13.3 2.8 2 0 0 2 2 2 0 ABC-2 family transporter protein Methyltransf_16 PF10294.9 CAM42100.1 - 1e-09 38.3 0.0 7.3e-06 25.8 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase DPM2 PF07297.12 CAM42101.1 - 1.3e-16 60.7 0.7 1.9e-16 60.1 0.7 1.3 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) GDI PF00996.18 CAM42102.1 - 3.1e-21 75.4 0.0 1.6e-09 36.8 0.0 3.1 2 1 0 2 2 2 2 GDP dissociation inhibitor Methyltransf_16 PF10294.9 CAM42102.1 - 5e-11 42.6 0.0 0.00012 21.8 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase MTS PF05175.14 CAM42102.1 - 0.077 12.5 0.1 0.98 8.9 0.1 2.4 1 1 1 2 2 2 0 Methyltransferase small domain UPF0060 PF02694.15 CAM42102.1 - 0.092 13.0 0.1 0.25 11.6 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised BCR, YnfA/UPF0060 family Nop14 PF04147.12 CAM42106.1 - 0.12 10.5 3.6 0.14 10.4 3.6 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 CAM42106.1 - 6.3 4.8 7.5 9.5 4.2 7.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi MFS_1 PF07690.16 CAM42107.2 - 2.3e-15 56.4 33.9 2e-12 46.7 14.0 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CAM42107.2 - 2.6e-08 33.2 5.4 2.6e-08 33.2 5.4 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter Inositol_P PF00459.25 CAM42108.1 - 6.7e-44 150.4 0.8 2.9e-21 76.2 0.0 2.2 2 0 0 2 2 2 2 Inositol monophosphatase family Kdo_hydroxy PF11004.8 CAM42108.1 - 0.092 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase DUF4897 PF16238.5 CAM42108.1 - 0.22 11.4 0.0 0.43 10.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4897) UQ_con PF00179.26 CAM42109.1 - 2.4e-34 118.0 0.0 3.2e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme BRE PF06113.12 CAM42109.1 - 0.26 10.1 0.0 0.35 9.6 0.0 1.1 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) ABC2_membrane PF01061.24 CAM42110.1 - 6.3e-39 133.6 18.7 6.3e-39 133.6 18.7 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 CAM42110.1 - 4.2e-19 69.4 0.0 6.9e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 CAM42110.1 - 0.0035 17.7 0.0 0.0073 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 CAM42110.1 - 0.0038 17.1 0.0 0.0068 16.3 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 CAM42110.1 - 0.0051 17.1 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 CAM42110.1 - 0.012 16.1 0.1 0.021 15.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CAM42110.1 - 0.017 14.9 0.5 0.035 13.8 0.5 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CAM42110.1 - 0.022 14.5 0.3 0.053 13.3 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PRK PF00485.18 CAM42110.1 - 0.06 13.1 0.0 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 CAM42110.1 - 0.073 13.5 0.0 0.52 10.7 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_21 PF13304.6 CAM42110.1 - 0.075 12.8 0.2 12 5.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 CAM42110.1 - 0.076 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain SMC_N PF02463.19 CAM42110.1 - 0.082 12.3 0.0 8.1 5.8 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain NB-ARC PF00931.22 CAM42110.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 CAM42110.1 - 0.11 13.1 0.0 0.23 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 CAM42110.1 - 0.12 12.4 0.1 0.25 11.4 0.1 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.6 CAM42110.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CAM42110.1 - 0.19 11.4 0.5 0.45 10.2 0.5 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CAM42110.1 - 0.2 11.0 0.2 1.1 8.6 0.0 2.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI ABC2_membrane_3 PF12698.7 CAM42110.1 - 2.1 7.4 19.7 0.13 11.3 14.4 1.6 2 0 0 2 2 2 0 ABC-2 family transporter protein HEAT PF02985.22 CAM42113.2 - 6.9e-19 66.3 26.4 0.0015 18.6 0.0 10.6 10 0 0 10 10 10 7 HEAT repeat HEAT_2 PF13646.6 CAM42113.2 - 1.5e-17 63.7 19.7 7e-05 23.1 1.8 6.9 4 2 3 7 7 7 6 HEAT repeats Adaptin_N PF01602.20 CAM42113.2 - 2.6e-05 23.0 0.3 2.7 6.4 0.0 3.6 3 1 0 3 3 3 3 Adaptin N terminal region Cnd1 PF12717.7 CAM42113.2 - 0.00025 21.1 1.8 0.34 10.9 0.1 4.3 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 CAM42113.2 - 0.00097 18.8 0.3 0.49 9.9 0.1 3.5 2 2 1 3 3 3 1 CLASP N terminal Cohesin_HEAT PF12765.7 CAM42113.2 - 0.38 11.1 2.5 0.91 9.9 0.1 2.7 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion EF-hand_8 PF13833.6 CAM42114.1 - 1.5e-07 31.2 0.0 0.1 12.4 0.0 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 CAM42114.1 - 6.3e-07 29.6 0.1 0.057 13.8 0.0 3.1 2 1 1 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CAM42114.1 - 1.3e-06 28.8 0.0 0.00018 21.9 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CAM42114.1 - 3.2e-05 23.5 0.2 0.35 10.9 0.0 3.9 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 CAM42114.1 - 0.0075 15.7 0.0 9.1 6.1 0.0 3.6 3 0 0 3 3 3 1 EF hand Retrotran_gag_2 PF14223.6 CAM42114.1 - 0.011 15.4 0.1 3.6 7.2 0.1 2.7 2 1 0 2 2 2 0 gag-polypeptide of LTR copia-type DUF2267 PF10025.9 CAM42114.1 - 0.011 15.9 0.3 2.1 8.6 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) DUF2087 PF09860.9 CAM42114.1 - 0.02 15.0 0.0 1.4 9.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2087) MAP65_ASE1 PF03999.12 CAM42115.1 - 1.4e-06 27.3 5.1 1.4e-06 27.3 5.1 3.3 4 1 0 4 4 4 1 Microtubule associated protein (MAP65/ASE1 family) Herpes_UL6 PF01763.16 CAM42115.1 - 0.012 14.2 0.2 0.023 13.2 0.2 1.4 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF5526 PF17664.1 CAM42115.1 - 1.4 8.5 11.0 0.023 14.2 1.2 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5526) Ribosomal_S3_C PF00189.20 CAM42116.1 - 1.4e-19 70.4 1.8 1.4e-19 70.4 1.8 2.2 2 1 1 3 3 3 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 CAM42116.1 - 1.8e-07 30.9 0.3 5e-07 29.5 0.3 1.7 2 0 0 2 2 2 1 KH domain Evr1_Alr PF04777.13 CAM42117.1 - 1e-22 80.4 1.7 2.1e-22 79.4 1.7 1.5 1 0 0 1 1 1 1 Erv1 / Alr family Get5_C PF18514.1 CAM42117.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 Get5 C-terminal domain ThiF PF00899.21 CAM42118.1 - 3.7e-49 167.3 0.0 5.3e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 ThiF family PglD_N PF17836.1 CAM42118.1 - 0.0016 19.1 0.0 0.0033 18.0 0.0 1.6 1 0 0 1 1 1 1 PglD N-terminal domain 2-Hacid_dh_C PF02826.19 CAM42118.1 - 0.0038 16.6 0.0 0.0083 15.5 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 CAM42118.1 - 0.012 15.2 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 CAM42118.1 - 0.012 15.3 0.1 0.037 13.7 0.1 1.8 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 CAM42118.1 - 0.023 13.9 0.3 0.047 12.9 0.3 1.5 1 0 0 1 1 1 0 FAD binding domain Sacchrp_dh_NADP PF03435.18 CAM42118.1 - 0.039 14.2 0.9 0.078 13.2 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 CAM42118.1 - 0.065 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Rad9 PF04139.13 CAM42119.2 - 6.2e-08 32.4 0.0 8.3e-05 22.2 0.0 2.4 2 1 0 2 2 2 2 Rad9 LD_cluster3 PF18180.1 CAM42119.2 - 0.17 11.5 0.1 0.43 10.2 0.1 1.6 1 0 0 1 1 1 0 SLOG cluster3 family Fer4_17 PF13534.6 CAM42120.1 - 4.2e-08 33.6 8.8 1.8e-06 28.4 0.8 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 CAM42120.1 - 2.2e-07 31.2 0.3 0.00051 20.4 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 CAM42120.1 - 0.00019 21.5 4.5 0.00054 20.0 4.5 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 CAM42120.1 - 0.0056 16.8 4.3 0.037 14.2 1.4 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 CAM42120.1 - 0.013 16.0 5.0 0.047 14.2 1.0 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_7 PF12838.7 CAM42120.1 - 0.073 13.7 4.3 0.33 11.6 4.5 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain Ribosomal_L6e PF01159.19 CAM42121.1 - 2.2e-28 99.0 0.7 1.5e-27 96.3 0.7 2.0 1 1 0 1 1 1 1 Ribosomal protein L6e KOW PF00467.29 CAM42121.1 - 0.00037 20.4 0.0 0.0015 18.4 0.0 2.1 1 1 1 2 2 2 1 KOW motif ParE-like_toxin PF15781.5 CAM42121.1 - 0.61 10.1 3.2 2.9 7.9 3.2 2.1 1 1 0 1 1 1 0 ParE-like toxin of type II bacterial toxin-antitoxin system OAD_gamma PF04277.13 CAM42121.1 - 7.1 7.3 10.8 0.78 10.4 5.5 2.0 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain ELFV_dehydrog PF00208.21 CAM42122.1 - 3.1e-48 164.6 0.0 5.5e-48 163.8 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 CAM42122.1 - 1.1e-16 59.7 0.0 4.1e-08 31.3 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase CLP1_N PF16573.5 CAM42122.1 - 0.16 12.2 0.1 1.4 9.2 0.0 2.3 2 0 0 2 2 2 0 N-terminal beta-sandwich domain of polyadenylation factor polyprenyl_synt PF00348.17 CAM42123.1 - 4.9e-63 212.6 0.0 5.9e-63 212.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase SQS_PSY PF00494.19 CAM42123.1 - 0.012 15.1 0.5 0.038 13.5 0.1 2.0 2 0 0 2 2 2 0 Squalene/phytoene synthase SKIP_SNW PF02731.15 CAM42124.1 - 4.1e-09 36.3 2.7 4.1e-09 36.3 2.7 2.6 1 1 1 2 2 2 1 SKIP/SNW domain RR_TM4-6 PF06459.12 CAM42124.1 - 3.7 7.3 9.9 7.8 6.2 9.9 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GREB1 PF15782.5 CAM42124.1 - 7.6 3.5 6.5 8.2 3.4 6.5 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Presenilin PF01080.17 CAM42124.1 - 8.9 5.0 5.8 15 4.2 5.8 1.3 1 0 0 1 1 1 0 Presenilin AhpC-TSA PF00578.21 CAM42125.1 - 2.4e-36 124.4 0.0 3.3e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CAM42125.1 - 2.1e-14 53.5 0.0 2.5e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CAM42125.1 - 3.8e-13 49.1 0.0 9.2e-13 47.8 0.0 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 CAM42125.1 - 0.0044 16.9 0.0 0.011 15.6 0.1 1.6 2 0 0 2 2 2 1 SCO1/SenC AhpC-TSA PF00578.21 CAM42127.1 - 3.1e-36 124.0 0.0 4.2e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CAM42127.1 - 2.4e-14 53.3 0.0 2.9e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CAM42127.1 - 3.1e-13 49.3 0.0 7.6e-13 48.1 0.0 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 CAM42127.1 - 0.013 15.5 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 SCO1/SenC TFIIB_C_1 PF18542.1 CAM42128.1 - 2.1e-42 143.1 1.3 6e-42 141.6 1.3 1.8 1 0 0 1 1 1 1 Transcription factor IIB C-terminal module 1 TF_Zn_Ribbon PF08271.12 CAM42128.1 - 3.3e-06 26.5 1.3 6.5e-06 25.6 1.3 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding zf-ribbon_3 PF13248.6 CAM42128.1 - 0.14 11.6 2.0 0.68 9.4 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DUF29 PF01724.16 CAM42128.1 - 0.15 12.3 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF29 Lar_restr_allev PF14354.6 CAM42128.1 - 0.31 11.5 2.3 0.48 10.8 0.6 2.1 2 0 0 2 2 2 0 Restriction alleviation protein Lar cNMP_binding PF00027.29 CAM42130.2 - 0.0013 18.7 0.0 0.0093 16.0 0.0 2.4 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Pkinase PF00069.25 CAM42131.2 - 5.9e-57 193.0 0.0 9.3e-57 192.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM42131.2 - 2e-39 135.4 0.0 3.5e-39 134.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 CAM42131.2 - 8.2e-29 99.5 0.4 1.2e-14 54.1 0.1 3.1 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Kinase-like PF14531.6 CAM42131.2 - 6.7e-08 32.2 0.0 2.1e-06 27.3 0.0 2.3 2 0 0 2 2 2 1 Kinase-like PAS PF00989.25 CAM42131.2 - 8.9e-08 32.1 0.0 3.5e-07 30.2 0.0 2.0 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 CAM42131.2 - 1.9e-07 31.3 0.0 1.1e-05 25.6 0.0 2.8 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.12 CAM42131.2 - 0.1 12.9 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 PAS fold RIO1 PF01163.22 CAM42131.2 - 0.18 11.4 0.0 0.4 10.2 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Ribosomal_60s PF00428.19 CAM42132.1 - 3.5e-23 82.0 13.1 4.4e-23 81.7 13.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Phage-MuB_C PF09077.11 CAM42132.1 - 0.012 15.5 3.0 0.019 14.8 3.0 1.5 1 1 0 1 1 1 0 Mu B transposition protein, C terminal RhoGAP PF00620.27 CAM42133.1 - 3e-12 46.6 0.0 5.6e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.23 CAM42133.1 - 8.3e-09 35.3 0.3 2.5e-08 33.7 0.0 1.9 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DnaJ PF00226.31 CAM42134.2 - 5.6e-25 87.2 1.5 8.6e-25 86.6 1.5 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 CAM42134.2 - 1.8e-18 67.1 0.0 1.5e-17 64.0 0.0 2.0 1 1 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 CAM42134.2 - 3.5e-07 30.5 12.7 7.3e-07 29.5 12.7 1.5 1 0 0 1 1 1 1 DnaJ central domain SabA_adhesion PF18304.1 CAM42134.2 - 0.22 10.7 0.1 0.35 10.1 0.1 1.2 1 0 0 1 1 1 0 SabA N-terminal extracellular adhesion domain Anti-TRAP PF15777.5 CAM42134.2 - 1.1 9.3 14.7 0.098 12.6 3.6 2.6 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein UFC1 PF08694.11 CAM42136.1 - 2.7e-78 261.0 0.1 3e-78 260.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.26 CAM42136.1 - 0.00053 19.6 0.2 0.00073 19.2 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CAM42136.1 - 0.011 16.0 0.0 0.014 15.7 0.0 1.2 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 CAM42136.1 - 0.1 12.3 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B SET PF00856.28 CAM42137.1 - 2.9e-08 34.3 0.0 6.7e-08 33.1 0.0 1.6 1 1 0 1 1 1 1 SET domain Mac PF12464.8 CAM42137.1 - 0.13 12.6 2.0 0.52 10.6 0.3 2.3 2 0 0 2 2 2 0 Maltose acetyltransferase Di19_C PF14571.6 CAM42138.1 - 0.031 14.8 0.2 0.071 13.6 0.2 1.5 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal Chorion_3 PF05387.11 CAM42138.1 - 0.32 10.6 3.2 0.53 9.9 3.2 1.3 1 0 0 1 1 1 0 Chorion family 3 IQ PF00612.27 CAM42139.2 - 3.9 7.5 29.9 0.94 9.4 1.1 5.6 5 0 0 5 5 5 0 IQ calmodulin-binding motif DNA_topoisoIV PF00521.20 CAM42140.1 - 1.6e-102 343.6 0.0 2.4e-102 343.0 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 CAM42140.1 - 4.7e-32 111.0 0.9 9.6e-32 110.0 0.9 1.6 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 CAM42140.1 - 6.9e-09 35.4 0.0 1.7e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 CAM42140.1 - 1.1e-08 35.5 0.0 3.8e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 CAM42140.1 - 2e-06 28.0 0.0 8.3e-06 26.0 0.0 2.1 1 0 0 1 1 1 1 Toprim domain SAB PF04382.13 CAM42140.1 - 0.038 14.1 0.2 0.11 12.6 0.2 1.8 1 0 0 1 1 1 0 SAB domain UCH PF00443.29 CAM42141.1 - 2.1e-38 132.3 0.0 3.3e-38 131.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 CAM42141.1 - 3.7e-11 42.8 0.0 5.5e-06 25.9 0.0 3.0 2 1 0 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.6 CAM42141.1 - 8.1e-09 35.5 0.0 0.0027 17.4 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Pol_alpha_B_N PF08418.10 CAM42141.1 - 1.2 9.0 4.7 1.6 8.7 3.5 1.7 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal PDEase_I PF00233.19 CAM42142.1 - 1.2e-68 231.4 0.0 4.4e-68 229.6 0.0 1.9 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 CAM42142.1 - 1.5e-29 103.3 0.0 1.4e-14 54.9 0.0 2.8 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 CAM42142.1 - 1.5e-19 70.7 0.1 7.4e-07 29.5 0.0 3.6 3 1 0 3 3 3 3 GAF domain GAF_3 PF13492.6 CAM42142.1 - 1e-08 35.6 0.0 0.003 17.9 0.0 2.9 3 1 0 3 3 3 2 GAF domain Occludin_ELL PF07303.13 CAM42142.1 - 0.09 13.5 0.0 0.22 12.3 0.0 1.6 1 0 0 1 1 1 0 Occludin homology domain Ribosomal_L11 PF00298.19 CAM42142.1 - 0.13 12.7 0.0 0.45 11.0 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein L11, RNA binding domain CorA PF01544.18 CAM42143.1 - 9.2e-23 81.0 8.4 1.6e-20 73.6 8.4 2.3 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein SHOCT PF09851.9 CAM42143.1 - 1.2e-05 24.8 0.0 2.2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Short C-terminal domain MIF4G PF02854.19 CAM42144.1 - 8.2e-11 41.9 0.1 1.5e-10 41.1 0.1 1.4 1 0 0 1 1 1 1 MIF4G domain Actin PF00022.19 CAM42145.1 - 9.9e-15 54.0 0.0 1e-14 54.0 0.0 1.0 1 0 0 1 1 1 1 Actin NIF PF03031.18 CAM42147.1 - 0.021 14.6 0.0 0.043 13.6 0.0 1.6 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase WHEP-TRS PF00458.20 CAM42148.1 - 0.064 13.4 0.6 0.13 12.4 0.6 1.5 1 0 0 1 1 1 0 WHEP-TRS domain RabGAP-TBC PF00566.18 CAM42149.1 - 3.7e-06 26.8 0.2 7.1e-06 25.8 0.2 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Peptidase_M91 PF14891.6 CAM42149.1 - 0.033 14.5 0.2 0.058 13.7 0.2 1.3 1 0 0 1 1 1 0 Effector protein SlyX PF04102.12 CAM42149.1 - 0.035 14.7 0.4 0.12 13.1 0.4 1.9 1 0 0 1 1 1 0 SlyX DUF2633 PF11119.8 CAM42149.1 - 1.3 9.0 4.9 4.8 7.2 0.8 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2633) Helicase_C_2 PF13307.6 CAM42150.2 - 3.2e-41 141.3 0.0 5.4e-41 140.6 0.0 1.4 1 1 0 1 1 1 1 Helicase C-terminal domain Methyltransf_31 PF13847.6 CAM42151.1 - 3.2e-09 36.7 0.0 6e-09 35.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAM42151.1 - 6.2e-08 33.2 0.0 2.1e-07 31.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAM42151.1 - 9.4e-05 23.0 0.0 0.00038 21.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 CAM42151.1 - 0.0012 17.9 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase PrmA PF06325.13 CAM42151.1 - 0.0012 18.3 0.0 0.0022 17.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 CAM42151.1 - 0.0019 17.2 0.0 0.0051 15.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 CAM42151.1 - 0.0039 17.9 0.0 0.011 16.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CAM42151.1 - 0.0074 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 CAM42151.1 - 0.11 13.5 0.1 0.42 11.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain 2OG-FeII_Oxy PF03171.20 CAM42152.2 - 0.0019 18.6 0.0 0.11 13.0 0.0 2.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Actin PF00022.19 CAM42153.2 - 2e-56 191.3 0.0 3e-54 184.2 0.0 2.0 1 1 0 1 1 1 1 Actin FtsA PF14450.6 CAM42153.2 - 0.065 13.7 0.0 0.09 13.2 0.0 1.3 1 0 0 1 1 1 0 Cell division protein FtsA DUF1796 PF08795.10 CAM42154.1 - 7.3e-40 136.7 0.0 1.3e-39 135.9 0.0 1.4 1 0 0 1 1 1 1 Putative papain-like cysteine peptidase (DUF1796) Nop PF01798.18 CAM42155.1 - 1e-81 273.8 0.6 1.4e-81 273.4 0.6 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CAM42155.1 - 0.00014 22.2 0.5 0.17 12.3 0.1 2.8 1 1 1 2 2 2 2 NOP5NT (NUC127) domain TMEM164 PF14808.6 CAM42156.1 - 1.9e-08 34.0 3.8 2.6e-08 33.5 3.6 1.4 1 1 0 1 1 1 1 TMEM164 family SecY PF00344.20 CAM42156.1 - 0.042 13.1 1.0 9.2 5.4 0.0 2.7 2 1 1 3 3 3 0 SecY translocase zf-RING_2 PF13639.6 CAM42158.2 - 1.1e-12 48.0 7.6 2.4e-12 47.0 7.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CAM42158.2 - 6.2e-07 29.0 2.6 1.3e-06 28.0 2.6 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CAM42158.2 - 9.1e-07 28.8 6.2 1.6e-06 28.0 6.2 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CAM42158.2 - 1e-06 28.4 7.6 1.9e-06 27.6 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CAM42158.2 - 1.1e-05 25.7 9.8 3.4e-05 24.0 9.8 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CAM42158.2 - 3e-05 23.8 5.7 5.6e-05 22.9 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CAM42158.2 - 0.00024 20.9 6.6 0.00044 20.0 6.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CAM42158.2 - 0.0019 18.1 5.8 0.0035 17.3 5.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CAM42158.2 - 0.027 14.5 4.9 0.073 13.1 4.9 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 CAM42158.2 - 0.029 14.3 5.2 0.06 13.2 5.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 CAM42158.2 - 0.034 14.3 7.7 0.73 10.1 7.7 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 CAM42158.2 - 0.08 12.6 4.6 0.16 11.6 4.6 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF5337 PF17272.2 CAM42158.2 - 0.081 12.8 0.2 0.081 12.8 0.2 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5337) Nucleo_P87 PF07267.11 CAM42158.2 - 0.095 11.5 0.2 0.12 11.2 0.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 zinc_ribbon_16 PF17034.5 CAM42158.2 - 0.2 11.9 1.4 0.39 10.9 1.4 1.4 1 0 0 1 1 1 0 Zinc-ribbon like family zf-RING_4 PF14570.6 CAM42158.2 - 0.78 9.6 6.9 1.6 8.6 6.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 CAM42158.2 - 2 8.8 6.2 3.5 8.0 6.2 1.4 1 0 0 1 1 1 0 RING-like domain MutS_V PF00488.21 CAM42159.1 - 1.1e-49 169.0 0.0 1.3e-48 165.5 0.0 2.2 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CAM42159.1 - 1.2e-21 77.8 0.1 2e-21 77.1 0.1 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 CAM42159.1 - 3.6e-20 72.3 0.0 6.3e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.18 CAM42159.1 - 0.021 15.2 0.0 0.037 14.4 0.0 1.4 1 0 0 1 1 1 0 MutS family domain IV tRNA-synt_1c PF00749.21 CAM42160.1 - 5.9e-104 347.3 0.0 7.8e-104 346.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 CAM42160.1 - 1.8e-39 135.4 0.0 3e-39 134.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain PCNA_N PF00705.18 CAM42161.1 - 8.3e-42 141.9 2.1 1.2e-41 141.4 1.3 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 CAM42161.1 - 2.5e-37 127.9 0.1 1.9e-19 70.1 0.2 2.4 2 0 0 2 2 2 2 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 CAM42161.1 - 7.3e-08 32.2 0.1 1.1e-07 31.6 0.1 1.2 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 CAM42161.1 - 0.00031 19.9 0.4 0.0047 16.0 0.4 2.1 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 CAM42161.1 - 0.011 14.8 0.0 0.21 10.7 0.0 2.1 2 0 0 2 2 2 0 Hus1-like protein Diphthami_syn_2 PF01902.17 CAM42161.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Diphthamide synthase GHMP_kinases_N PF00288.26 CAM42162.1 - 3.1e-13 49.7 0.8 3.1e-13 49.7 0.8 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CAM42162.1 - 8.3e-07 29.3 0.4 1.1e-05 25.7 0.3 2.3 2 0 0 2 2 2 1 GHMP kinases C terminal Gpr1_Fun34_YaaH PF01184.19 CAM42163.1 - 0.0021 17.7 0.1 0.0026 17.4 0.1 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family ICE2 PF08426.10 CAM42163.1 - 0.0099 15.0 0.0 0.012 14.8 0.0 1.1 1 0 0 1 1 1 1 ICE2 Ribosomal_L7Ae PF01248.26 CAM42164.1 - 4e-25 87.4 0.1 4.7e-25 87.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 CAM42164.1 - 3.3e-05 23.7 0.0 5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 CAM42164.1 - 0.0022 18.0 0.1 0.0026 17.9 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PDEase_I PF00233.19 CAM42165.1 - 1.1e-68 231.5 0.0 3.7e-68 229.8 0.0 1.9 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 CAM42165.1 - 3.8e-29 102.0 0.1 1.4e-14 54.9 0.0 3.0 3 0 0 3 3 3 2 GAF domain GAF_2 PF13185.6 CAM42165.1 - 1.3e-17 64.4 0.0 7.4e-07 29.5 0.0 3.4 3 0 0 3 3 3 2 GAF domain GAF_3 PF13492.6 CAM42165.1 - 5.3e-09 36.5 0.1 0.0023 18.3 0.0 3.1 3 1 0 3 3 3 2 GAF domain Glyc_hyd_38C_2 PF18230.1 CAM42166.1 - 0.025 14.7 0.4 0.13 12.4 0.2 2.3 2 0 0 2 2 2 0 Glycosyl hydrolases family 38 C-terminal sub-domain COG5 PF10392.9 CAM42168.1 - 0.044 13.9 0.1 0.069 13.3 0.1 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Sld5 PF05916.11 CAM42168.1 - 0.12 12.9 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 GINS complex protein Presenilin PF01080.17 CAM42170.1 - 1.4e-74 251.3 32.0 1.4e-52 178.9 19.0 2.0 1 1 1 2 2 2 2 Presenilin Wyosine_form PF08608.12 CAM42171.1 - 1.6e-17 63.6 0.0 4e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 CAM42171.1 - 1.7e-16 61.1 0.0 3.7e-16 60.0 0.0 1.7 1 1 0 1 1 1 1 Radical SAM superfamily Paf67 PF10255.9 CAM42171.1 - 0.12 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 Pkinase PF00069.25 CAM42173.1 - 8.7e-57 192.5 0.0 1.2e-56 192.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM42173.1 - 1.7e-25 89.8 0.0 4.4e-25 88.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase FYVE PF01363.21 CAM42173.1 - 3.8e-13 49.4 7.2 9.3e-13 48.1 7.2 1.6 1 0 0 1 1 1 1 FYVE zinc finger APH PF01636.23 CAM42173.1 - 0.00011 22.3 0.1 0.00084 19.3 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CAM42173.1 - 0.00092 18.1 0.0 0.0013 17.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FYVE_2 PF02318.16 CAM42173.1 - 0.0018 18.5 5.4 0.0018 18.5 5.4 1.9 2 0 0 2 2 2 1 FYVE-type zinc finger DZR PF12773.7 CAM42173.1 - 0.012 15.6 6.7 0.15 12.1 0.2 2.8 3 0 0 3 3 3 0 Double zinc ribbon Choline_kinase PF01633.20 CAM42173.1 - 0.021 14.4 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 CAM42173.1 - 0.096 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like zf-RING_5 PF14634.6 CAM42173.1 - 0.1 12.5 11.7 0.076 13.0 9.6 2.0 2 0 0 2 2 2 0 zinc-RING finger domain NOB1_Zn_bind PF08772.11 CAM42173.1 - 3.6 7.8 8.1 2.2 8.5 6.0 1.8 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zf-RING_2 PF13639.6 CAM42173.1 - 4.7 7.6 12.8 5.6 7.4 10.7 2.3 2 0 0 2 2 2 0 Ring finger domain Prok-RING_4 PF14447.6 CAM42173.1 - 9.4 6.2 10.9 1.5 8.7 5.9 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Cnd1 PF12717.7 CAM42174.1 - 1.1e-18 67.8 5.5 4.4e-16 59.3 0.2 4.4 3 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CAM42174.1 - 8.2e-06 25.7 3.7 1.2 9.6 0.0 6.1 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 CAM42174.1 - 3.3e-05 24.2 3.0 3.6 8.0 0.1 5.3 3 2 2 5 5 5 3 HEAT repeats Cnd1_N PF12922.7 CAM42174.1 - 0.004 17.0 0.0 0.014 15.2 0.0 1.9 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd3 PF12719.7 CAM42174.1 - 0.0041 16.4 1.1 0.03 13.5 0.1 2.6 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain LEAP-2 PF07359.11 CAM42174.1 - 0.055 13.3 0.0 0.27 11.1 0.0 2.2 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Nipped-B_C PF12830.7 CAM42174.1 - 0.11 12.4 1.2 10 6.0 0.0 3.7 5 0 0 5 5 5 0 Sister chromatid cohesion C-terminus SR-25 PF10500.9 CAM42175.1 - 0.025 14.2 7.7 0.038 13.6 7.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein YL1 PF05764.13 CAM42175.1 - 0.13 12.4 7.1 0.26 11.4 7.1 1.5 1 0 0 1 1 1 0 YL1 nuclear protein BCDHK_Adom3 PF10436.9 CAM42176.1 - 2.3e-25 89.3 0.0 1.3e-24 86.8 0.0 1.9 1 1 1 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CAM42176.1 - 0.14 12.7 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ANTH PF07651.16 CAM42177.1 - 1.5e-25 89.7 0.1 2.4e-25 89.1 0.1 1.3 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 CAM42177.1 - 0.0015 18.5 0.0 0.0028 17.7 0.0 1.4 1 0 0 1 1 1 1 ENTH domain Rz1 PF06085.11 CAM42177.1 - 0.025 14.3 1.2 0.025 14.3 1.2 2.3 2 0 0 2 2 2 0 Lipoprotein Rz1 precursor Ribosomal_L22 PF00237.19 CAM42179.1 - 1.1e-31 109.1 0.3 1.4e-31 108.8 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e FAM92 PF06730.11 CAM42182.1 - 0.024 14.0 0.0 0.098 12.1 0.0 2.0 1 0 0 1 1 1 0 FAM92 protein zf-RING_2 PF13639.6 CAM42183.1 - 2.9e-08 33.9 5.2 2.9e-08 33.9 5.2 5.2 3 2 2 5 5 5 1 Ring finger domain zf-RING_11 PF17123.5 CAM42183.1 - 3.1e-07 30.0 5.1 2.1e-06 27.3 5.1 2.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CAM42183.1 - 4.2e-06 26.7 1.2 4.2e-06 26.7 1.2 3.4 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CAM42183.1 - 0.0001 22.1 2.6 0.0001 22.1 2.6 3.9 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CAM42183.1 - 0.00018 21.3 2.2 0.00018 21.3 2.2 4.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CAM42183.1 - 0.00077 19.7 2.9 0.00077 19.7 2.9 4.2 2 1 2 4 4 4 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CAM42183.1 - 0.0027 17.6 5.1 0.0027 17.6 5.1 4.7 4 2 0 4 4 4 1 zinc-RING finger domain DUF3592 PF12158.8 CAM42184.1 - 6.9e-09 35.9 0.1 8.8e-09 35.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3592) Enkurin PF13864.6 CAM42185.1 - 3.2e-17 62.7 1.5 4.4e-17 62.3 1.5 1.2 1 0 0 1 1 1 1 Calmodulin-binding PARP_regulatory PF01358.18 CAM42186.1 - 1.5e-11 43.8 0.0 2.2e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Poly A polymerase regulatory subunit UPF0182 PF03699.13 CAM42186.1 - 0.051 11.7 0.0 0.072 11.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) WD40 PF00400.32 CAM42187.1 - 0.023 15.6 11.0 11 7.1 0.0 4.8 4 0 0 4 4 4 0 WD domain, G-beta repeat Blt1_C PF17183.4 CAM42187.1 - 0.2 11.3 0.0 0.42 10.3 0.0 1.4 1 0 0 1 1 1 0 Get5 carboxyl domain Ank_4 PF13637.6 CAM42188.1 - 1.4e-37 127.6 8.5 2.4e-10 40.7 0.0 5.1 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 CAM42188.1 - 8.6e-37 125.6 6.7 1.2e-16 61.0 0.8 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CAM42188.1 - 2.9e-32 110.3 6.6 5.6e-10 39.3 0.1 5.1 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 CAM42188.1 - 6.6e-30 102.2 5.0 2.3e-06 27.8 0.0 7.4 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 CAM42188.1 - 6e-28 93.8 4.1 9.4e-05 22.5 0.0 7.2 7 0 0 7 7 7 6 Ankyrin repeat TPR_1 PF00515.28 CAM42188.1 - 2.4e-11 43.0 1.7 0.0063 16.3 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CAM42188.1 - 1.8e-08 33.8 1.8 0.15 12.3 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 CAM42188.1 - 7.2e-05 22.9 2.6 0.7 10.4 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CAM42188.1 - 8.5e-05 22.2 1.2 0.0046 16.6 0.3 2.9 2 1 1 3 3 3 1 TPR repeat ANAPC3 PF12895.7 CAM42188.1 - 0.00074 19.7 1.7 0.0018 18.5 1.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CAM42188.1 - 0.032 14.5 0.4 41 4.7 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat BAT PF15915.5 CAM42188.1 - 0.1 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 GAF and HTH_10 associated domain PEX11 PF05648.14 CAM42189.1 - 3.7e-11 42.9 3.3 1.9e-07 30.8 0.1 2.1 1 1 1 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) AcetylCoA_hyd_C PF13336.6 CAM42189.1 - 0.025 14.5 0.3 1.7 8.5 0.1 2.2 2 0 0 2 2 2 0 Acetyl-CoA hydrolase/transferase C-terminal domain Phosducin PF02114.16 CAM42191.2 - 9.8e-08 31.3 0.0 1.2e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Phosducin MRC1 PF09444.10 CAM42191.2 - 0.027 15.0 1.0 0.044 14.3 1.0 1.3 1 0 0 1 1 1 0 MRC1-like domain Pertus-S5-tox PF09276.10 CAM42191.2 - 0.17 12.0 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Pertussis toxin S5 subunit AAA PF00004.29 CAM42192.1 - 2.6e-30 105.5 0.0 7.5e-26 91.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CAM42192.1 - 1.2e-10 41.8 0.0 0.00083 19.6 0.0 2.9 2 1 0 2 2 2 2 AAA domain NACHT PF05729.12 CAM42192.1 - 1.3e-09 38.2 0.0 0.00011 22.2 0.1 3.0 3 0 0 3 3 3 2 NACHT domain AAA_16 PF13191.6 CAM42192.1 - 1.7e-07 31.8 8.6 0.00013 22.4 0.1 4.2 2 2 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 CAM42192.1 - 2.1e-06 27.8 0.0 0.00045 20.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 CAM42192.1 - 3.7e-06 26.9 0.1 0.015 15.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase RNA_helicase PF00910.22 CAM42192.1 - 6.5e-06 26.5 0.0 0.0046 17.3 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 CAM42192.1 - 1.3e-05 25.4 0.1 0.015 15.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 CAM42192.1 - 7e-05 23.4 0.7 0.19 12.3 0.1 2.4 2 0 0 2 2 2 2 ABC transporter DUF815 PF05673.13 CAM42192.1 - 8.5e-05 21.8 0.0 0.054 12.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_29 PF13555.6 CAM42192.1 - 0.00012 21.8 2.0 0.15 11.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_7 PF12775.7 CAM42192.1 - 0.00014 21.4 0.1 0.61 9.6 0.1 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region TsaE PF02367.17 CAM42192.1 - 0.00018 21.5 0.1 0.53 10.3 0.1 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 CAM42192.1 - 0.0004 20.7 0.0 0.022 15.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CAM42192.1 - 0.00063 19.5 0.1 1.2 8.8 0.0 2.5 2 1 0 2 2 2 2 AAA domain Rad17 PF03215.15 CAM42192.1 - 0.00086 19.3 0.5 0.14 12.1 0.1 2.6 3 0 0 3 3 2 1 Rad17 P-loop domain AAA_25 PF13481.6 CAM42192.1 - 0.00094 18.8 0.0 0.45 10.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 CAM42192.1 - 0.0015 17.8 0.0 0.2 10.8 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Mg_chelatase PF01078.21 CAM42192.1 - 0.0022 17.4 0.0 0.18 11.1 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_8 PF12780.7 CAM42192.1 - 0.0024 17.2 0.0 0.031 13.6 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_30 PF13604.6 CAM42192.1 - 0.0025 17.6 0.0 0.15 11.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 CAM42192.1 - 0.0037 17.0 0.0 0.17 11.6 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain TIP49 PF06068.13 CAM42192.1 - 0.0043 16.3 0.0 0.008 15.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 CAM42192.1 - 0.0044 16.8 0.0 0.15 11.8 0.0 2.6 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_14 PF13173.6 CAM42192.1 - 0.0046 17.0 0.0 1.1 9.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 CAM42192.1 - 0.0064 16.4 0.0 0.38 10.6 0.0 2.6 3 0 0 3 3 2 1 ATPase domain predominantly from Archaea AAA_23 PF13476.6 CAM42192.1 - 0.0078 16.7 0.4 3.5 8.1 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CAM42192.1 - 0.0091 16.5 0.0 0.22 12.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 CAM42192.1 - 0.011 15.5 0.0 1.7 8.3 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 CAM42192.1 - 0.013 14.8 0.2 0.92 8.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin PRK PF00485.18 CAM42192.1 - 0.022 14.5 0.1 1.8 8.2 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_PrkA PF08298.11 CAM42192.1 - 0.026 13.5 0.0 0.11 11.3 0.0 1.8 2 0 0 2 2 2 0 PrkA AAA domain TniB PF05621.11 CAM42192.1 - 0.03 13.7 0.0 9.4 5.6 0.0 2.6 3 0 0 3 3 2 0 Bacterial TniB protein Roc PF08477.13 CAM42192.1 - 0.031 14.5 0.0 7.1 6.9 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Cytidylate_kin PF02224.18 CAM42192.1 - 0.036 13.8 0.0 0.082 12.6 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase FtsK_SpoIIIE PF01580.18 CAM42192.1 - 0.038 13.3 0.9 0.12 11.7 0.1 2.2 3 0 0 3 3 2 0 FtsK/SpoIIIE family G-alpha PF00503.20 CAM42192.1 - 0.063 12.4 0.3 5.4 6.1 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit MMR_HSR1 PF01926.23 CAM42192.1 - 0.096 12.8 0.0 11 6.1 0.1 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Sigma54_activ_2 PF14532.6 CAM42192.1 - 0.11 12.6 0.0 6.8 6.8 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain SIP1 PF04938.12 CAM42192.1 - 0.4 10.4 1.7 0.69 9.6 0.2 2.0 2 0 0 2 2 2 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) NTP_transf_3 PF12804.7 CAM42192.1 - 0.6 10.5 4.0 0.47 10.8 0.2 2.4 2 1 0 2 2 2 0 MobA-like NTP transferase domain HEAT PF02985.22 CAM42193.1 - 2.3e-10 39.8 18.3 0.63 10.4 0.0 7.4 7 0 0 7 7 7 5 HEAT repeat HEAT_2 PF13646.6 CAM42193.1 - 7.5e-08 32.7 11.6 0.0057 17.0 0.0 4.6 4 1 0 4 4 4 2 HEAT repeats Vac14_Fab1_bd PF12755.7 CAM42193.1 - 0.00017 22.1 0.9 2.4 8.8 0.1 4.3 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 CAM42193.1 - 0.0016 18.5 0.2 4.2 7.4 0.0 3.4 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CAM42193.1 - 0.0049 15.5 0.3 0.42 9.1 0.0 3.3 2 1 0 3 3 3 1 Adaptin N terminal region TFIIS_M PF07500.14 CAM42195.1 - 8.8e-18 64.8 1.2 1.6e-17 64.0 1.2 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 CAM42195.1 - 1.8e-14 53.3 4.1 3e-14 52.6 4.1 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Baculo_LEF5_C PF11792.8 CAM42195.1 - 8.7e-05 22.1 0.4 0.0003 20.4 0.5 1.9 2 0 0 2 2 2 1 Baculoviridae late expression factor 5 C-terminal domain zf-DNL PF05180.12 CAM42195.1 - 0.01 15.8 0.5 0.023 14.6 0.5 1.6 1 0 0 1 1 1 0 DNL zinc finger CBP4 PF07960.11 CAM42195.1 - 0.03 14.2 0.1 0.067 13.0 0.1 1.5 1 0 0 1 1 1 0 CBP4 Elf1 PF05129.13 CAM42195.1 - 0.055 13.5 1.1 0.11 12.5 1.1 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like UCH_1 PF13423.6 CAM42195.1 - 0.058 13.0 0.6 0.076 12.6 0.6 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase U83 PF17465.2 CAM42195.1 - 0.1 12.7 0.3 3.8 7.7 0.0 2.7 2 1 0 2 2 2 0 Chemokine-like protein, HHV-6 U83 gene product zf-CSL PF05207.13 CAM42195.1 - 0.1 12.3 0.3 0.18 11.6 0.3 1.4 1 0 0 1 1 1 0 CSL zinc finger Pkinase PF00069.25 CAM42197.1 - 2.2e-51 174.8 0.0 2.1e-50 171.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM42197.1 - 2.2e-25 89.5 0.0 2.4e-18 66.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase FHA PF00498.26 CAM42197.1 - 7.6e-14 51.8 0.1 1.9e-13 50.5 0.1 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CAM42197.1 - 9.1e-09 35.5 0.0 3.1e-08 33.8 0.0 1.9 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain APH PF01636.23 CAM42197.1 - 0.00063 19.7 0.2 0.39 10.6 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CAM42197.1 - 0.038 13.3 0.0 0.18 11.1 0.0 2.0 3 0 0 3 3 3 0 Kinase-like RIO1 PF01163.22 CAM42197.1 - 0.14 11.7 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family CAF1C_H4-bd PF12265.8 CAM42198.1 - 1.8e-10 40.9 0.2 5.3e-10 39.4 0.1 1.9 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 CAM42198.1 - 0.00092 19.5 2.2 0.4 11.0 0.2 3.6 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CAM42198.1 - 0.011 16.6 0.5 0.011 16.6 0.5 4.7 5 0 0 5 5 5 0 WD domain, G-beta repeat DEAD PF00270.29 CAM42199.1 - 8.2e-32 110.4 0.2 2.2e-31 109.0 0.2 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAM42199.1 - 2.8e-16 59.8 0.0 1e-15 58.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAM42199.1 - 1.2e-06 28.6 0.0 4.2e-06 26.9 0.0 1.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Metallophos PF00149.28 CAM42202.2 - 1.6e-07 32.0 0.0 3.5e-06 27.6 0.0 2.3 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase WD40 PF00400.32 CAM42203.1 - 2.8e-07 31.1 5.0 0.018 15.9 0.1 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat tify PF06200.14 CAM42203.1 - 0.64 9.4 5.3 1.8 8.0 0.2 2.8 3 0 0 3 3 3 0 tify domain NIF PF03031.18 CAM42204.1 - 1.7e-31 109.1 0.6 2.4e-31 108.6 0.6 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase PF00702.26 CAM42204.1 - 0.04 14.2 0.4 1.2 9.4 0.0 2.9 3 1 1 4 4 4 0 haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 CAM42204.1 - 0.11 12.0 1.0 2 7.8 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2608) zf-RING_2 PF13639.6 CAM42205.1 - 2.2e-05 24.7 8.9 7e-05 23.1 8.9 2.0 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CAM42205.1 - 0.016 15.5 7.5 0.073 13.4 7.5 2.3 1 0 0 1 1 1 0 RING-H2 zinc finger domain Ribonuc_P_40 PF08584.11 CAM42205.1 - 0.11 11.7 1.8 0.24 10.7 0.0 2.2 2 0 0 2 2 2 0 Ribonuclease P 40kDa (Rpp40) subunit zf-ANAPC11 PF12861.7 CAM42205.1 - 0.19 11.8 6.8 0.24 11.5 4.6 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 CAM42205.1 - 0.24 11.3 7.6 0.63 10.0 7.6 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Macoilin PF09726.9 CAM42205.1 - 0.34 9.4 2.7 0.51 8.8 2.7 1.2 1 0 0 1 1 1 0 Macoilin family RINGv PF12906.7 CAM42205.1 - 0.55 10.4 7.4 1.5 9.0 7.4 1.8 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 CAM42205.1 - 1.3 9.2 10.7 0.086 13.0 5.0 2.1 2 0 0 2 2 2 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 CAM42205.1 - 1.6 8.7 4.6 3.9 7.4 4.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Fumerase_C PF05683.12 CAM42207.2 - 4e-86 287.6 0.0 1.1e-85 286.1 0.0 1.7 2 0 0 2 2 2 1 Fumarase C-terminus Fumerase PF05681.14 CAM42207.2 - 4.6e-80 268.9 0.0 6.3e-80 268.5 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Rsm22 PF09243.10 CAM42208.1 - 4.7e-29 101.5 4.7 1.6e-17 63.7 0.2 3.2 4 0 0 4 4 4 2 Mitochondrial small ribosomal subunit Rsm22 Phosphodiest PF01663.22 CAM42209.2 - 2.4e-10 40.6 0.0 4.9e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CAM42209.2 - 0.086 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Sulfatase MerE PF05052.12 CAM42210.1 - 0.26 11.2 2.7 0.8 9.7 1.1 2.1 2 0 0 2 2 2 0 MerE protein Nuc_sug_transp PF04142.15 CAM42211.1 - 1.5e-56 191.9 21.1 2.8e-54 184.4 16.8 2.7 3 0 0 3 3 3 2 Nucleotide-sugar transporter EamA PF00892.20 CAM42211.1 - 1.9 8.7 31.5 0.29 11.3 4.8 3.1 2 1 0 2 2 2 0 EamA-like transporter family Aminotran_1_2 PF00155.21 CAM42212.1 - 7.1e-71 239.3 0.0 8e-71 239.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF512 PF04459.12 CAM42212.1 - 0.018 14.3 0.0 0.79 9.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF512) DASH_Spc19 PF08287.11 CAM42213.1 - 2.9 7.8 10.6 0.31 10.9 3.4 2.7 1 1 1 2 2 2 0 Spc19 TPR_2 PF07719.17 CAM42215.1 - 0.0034 17.4 0.1 1.5 9.1 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat NAD_binding_9 PF13454.6 CAM42215.1 - 0.016 15.2 0.9 0.14 12.1 0.2 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding SET PF00856.28 CAM42215.1 - 0.077 13.4 0.1 0.16 12.3 0.1 1.6 1 0 0 1 1 1 0 SET domain PHD PF00628.29 CAM42215.1 - 0.25 11.3 5.0 0.61 10.0 5.0 1.7 1 0 0 1 1 1 0 PHD-finger Peptidase_C12 PF01088.21 CAM42217.1 - 1.3e-57 195.0 0.0 1.7e-57 194.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 CAM42217.1 - 4.6e-12 45.7 0.7 1e-11 44.5 0.7 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Nuc_sug_transp PF04142.15 CAM42219.1 - 2.3e-56 191.3 22.4 4.3e-54 183.8 18.1 2.7 3 0 0 3 3 3 2 Nucleotide-sugar transporter EamA PF00892.20 CAM42219.1 - 4.8 7.4 31.7 0.77 9.9 5.4 3.1 2 1 0 2 2 2 0 EamA-like transporter family Vpu PF00558.19 CAM42221.1 - 0.076 12.8 0.3 0.076 12.8 0.3 1.7 2 0 0 2 2 2 0 Vpu protein Stealth_CR2 PF11380.8 CAM42222.2 - 2.3e-11 43.8 0.0 4.5e-09 36.4 0.0 2.3 2 0 0 2 2 2 2 Stealth protein CR2, conserved region 2 Stealth_CR2 PF11380.8 CAM42223.1 - 3.2e-11 43.4 0.0 5.2e-09 36.3 0.0 2.7 2 0 0 2 2 2 2 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 CAM42223.1 - 0.09 12.7 7.5 0.036 14.0 0.7 2.8 2 0 0 2 2 2 0 Stealth protein CR3, conserved region 3 Kelch_4 PF13418.6 CAM42224.1 - 5.9e-29 99.8 6.9 1.2e-06 28.5 0.0 7.5 5 2 1 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 CAM42224.1 - 1.8e-19 69.3 5.8 2.9e-08 33.5 0.0 6.2 7 0 0 7 7 7 3 Kelch motif Kelch_6 PF13964.6 CAM42224.1 - 2.6e-13 49.7 7.5 0.0053 17.0 0.0 7.1 6 1 1 7 7 7 4 Kelch motif Kelch_2 PF07646.15 CAM42224.1 - 2.6e-08 33.5 0.2 0.071 13.1 0.0 5.4 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 CAM42224.1 - 2.7e-08 33.9 18.9 0.0015 18.7 0.1 10.0 12 0 0 12 12 12 2 Galactose oxidase, central domain Kelch_1 PF01344.25 CAM42224.1 - 4.9e-06 26.0 4.4 0.044 13.4 0.0 5.9 6 0 0 6 6 6 1 Kelch motif LRR_8 PF13855.6 CAM42225.1 - 3.5e-39 132.4 65.0 2.6e-07 30.3 0.7 11.6 7 4 4 11 11 11 10 Leucine rich repeat LRR_4 PF12799.7 CAM42225.1 - 8.7e-39 130.9 58.2 2.5e-05 24.5 0.4 13.6 9 4 5 15 15 15 15 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CAM42225.1 - 3.3e-35 121.1 19.2 3.6e-08 33.1 0.0 8.3 6 3 3 9 9 9 8 Leucine-rich repeat LRR_6 PF13516.6 CAM42225.1 - 4.2e-06 26.4 39.9 5.1 7.4 0.0 14.9 17 0 0 17 17 17 4 Leucine Rich repeat Dicer_dimer PF03368.14 CAM42226.1 - 0.069 13.3 0.0 0.23 11.7 0.1 1.8 2 0 0 2 2 2 0 Dicer dimerisation domain MPP6 PF10175.9 CAM42226.1 - 0.11 13.1 1.8 0.27 11.7 0.1 2.1 2 0 0 2 2 2 0 M-phase phosphoprotein 6 Cbl_N PF02262.16 CAM42227.1 - 0.041 13.9 2.1 0.65 10.0 0.0 2.8 2 0 0 2 2 2 0 CBL proto-oncogene N-terminal domain 1 T2SSG PF08334.11 CAM42227.1 - 0.5 10.5 1.8 4 7.5 0.3 2.6 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein G TetR_C_26 PF17934.1 CAM42227.1 - 2.1 8.7 7.9 0.65 10.3 4.4 2.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TFIID-31kDa PF02291.15 CAM42228.1 - 0.0047 17.0 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit DnaJ PF00226.31 CAM42228.1 - 0.11 12.6 0.1 0.23 11.6 0.1 1.6 1 0 0 1 1 1 0 DnaJ domain ENT PF03735.14 CAM42229.1 - 0.00023 21.2 0.4 0.00049 20.1 0.0 1.7 2 0 0 2 2 2 1 ENT domain TRM13 PF05206.14 CAM42230.1 - 4.7e-15 55.8 0.1 2e-14 53.7 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase TRM13 Methyltransf_32 PF13679.6 CAM42230.1 - 0.0008 19.4 0.1 0.012 15.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain LapA_dom PF06305.11 CAM42233.1 - 0.00056 19.7 0.2 0.00085 19.1 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain WBP-1 PF11669.8 CAM42233.1 - 0.0081 16.8 0.5 0.016 15.8 0.5 1.5 1 1 0 1 1 1 1 WW domain-binding protein 1 BT1 PF03092.16 CAM42233.1 - 0.02 13.2 0.0 0.024 12.9 0.0 1.1 1 0 0 1 1 1 0 BT1 family DUF4381 PF14316.6 CAM42233.1 - 0.063 13.5 1.9 0.08 13.2 1.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4381) Cytadhesin_P30 PF07271.11 CAM42233.1 - 0.085 12.4 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 EphA2_TM PF14575.6 CAM42234.1 - 0.027 15.4 0.1 0.03 15.2 0.1 1.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SIT PF15330.6 CAM42234.1 - 0.051 14.0 0.0 0.062 13.7 0.0 1.1 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Glyco_hydro_70 PF02324.16 CAM42235.1 - 0.11 10.7 0.2 0.14 10.3 0.2 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 SMC_ScpB PF04079.16 CAM42236.1 - 0.2 11.3 0.0 0.49 10.0 0.0 1.6 2 0 0 2 2 2 0 Segregation and condensation complex subunit ScpB NopRA1 PF16201.5 CAM42237.2 - 1.8e-08 34.2 0.1 8.5e-08 32.0 0.1 2.3 1 1 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 Npa1 PF11707.8 CAM42237.2 - 6.1e-07 29.1 0.0 1.4e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal MOR2-PAG1_N PF14222.6 CAM42237.2 - 0.034 13.1 0.1 0.069 12.1 0.1 1.4 1 0 0 1 1 1 0 Cell morphogenesis N-terminal Arm PF00514.23 CAM42237.2 - 0.3 11.2 2.8 1.7 8.8 0.7 3.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat SNF2_N PF00176.23 CAM42238.2 - 8.6e-34 116.8 0.0 1.3e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CAM42238.2 - 3.4e-10 40.2 0.0 1e-09 38.7 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAM42238.2 - 1.5e-07 31.5 0.0 3e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TniB PF05621.11 CAM42238.2 - 0.064 12.7 0.3 0.25 10.7 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein UCH PF00443.29 CAM42239.1 - 9.5e-45 153.1 0.0 1.4e-44 152.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CAM42239.1 - 3.4e-10 40.0 0.3 4.2e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Kinesin PF00225.23 CAM42241.1 - 1.6e-90 303.4 0.0 2.1e-90 303.0 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CAM42241.1 - 1.7e-17 63.7 0.0 3.3e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Peptidase_C97 PF05903.14 CAM42242.1 - 4.1e-28 98.1 0.0 7.8e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 CAM42242.1 - 0.0074 16.6 0.5 0.022 15.1 0.0 1.9 2 0 0 2 2 2 1 Lecithin retinol acyltransferase Axin_b-cat_bind PF08833.10 CAM42242.1 - 3.6 7.8 5.9 2.6 8.2 0.5 3.1 2 0 0 2 2 2 0 Axin beta-catenin binding domain HEAT_2 PF13646.6 CAM42243.1 - 0.0037 17.6 2.8 1.3 9.5 0.1 3.7 2 1 1 3 3 3 2 HEAT repeats Pkinase PF00069.25 CAM42244.1 - 5.9e-37 127.5 0.0 1.5e-36 126.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM42244.1 - 2.1e-12 46.9 0.0 1e-11 44.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CAM42244.1 - 0.076 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TGFb_propeptide PF00688.18 CAM42244.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 TGF-beta propeptide Sugar_tr PF00083.24 CAM42245.1 - 1.2e-120 403.5 35.1 1.3e-120 403.3 35.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAM42245.1 - 3.1e-30 105.3 72.7 7e-28 97.6 43.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CAM42245.1 - 0.00038 19.0 3.4 0.00038 19.0 3.4 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF523 PF04463.12 CAM42248.1 - 2.8e-13 50.1 0.1 3e-07 30.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF523) zf-Tim10_DDP PF02953.15 CAM42249.1 - 0.00097 18.7 2.6 0.0014 18.3 2.6 1.4 1 1 0 1 1 1 1 Tim10/DDP family zinc finger SRP54 PF00448.22 CAM42250.1 - 1.1e-72 243.8 0.6 2.3e-72 242.7 0.6 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 CAM42250.1 - 5.6e-25 87.8 1.2 5.6e-25 87.8 1.2 4.3 4 1 0 4 4 4 1 Signal peptide binding domain SRP54_N PF02881.19 CAM42250.1 - 8e-14 51.6 4.7 8.1e-14 51.6 2.7 2.2 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 CAM42250.1 - 1.3e-05 24.8 0.2 4.9e-05 23.0 0.2 1.9 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 CAM42250.1 - 9.2e-05 22.9 1.2 0.00022 21.7 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CAM42250.1 - 9.9e-05 22.5 0.1 0.00026 21.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 CAM42250.1 - 0.00034 20.4 0.2 0.0011 18.7 0.2 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CAM42250.1 - 0.00044 20.5 0.5 0.022 15.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CAM42250.1 - 0.00099 18.4 0.0 0.0022 17.3 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin MeaB PF03308.16 CAM42250.1 - 0.001 18.1 0.0 0.0036 16.3 0.0 1.8 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GhoS PF11080.8 CAM42250.1 - 0.0017 18.3 0.2 4.3 7.4 0.1 3.4 4 0 0 4 4 3 1 Endoribonuclease GhoS AAA_16 PF13191.6 CAM42250.1 - 0.0022 18.4 0.6 0.0065 16.9 0.1 2.0 1 1 1 2 2 2 1 AAA ATPase domain CbiA PF01656.23 CAM42250.1 - 0.0038 17.3 0.0 0.01 15.9 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Methyltransf_24 PF13578.6 CAM42250.1 - 0.0062 17.5 0.0 0.016 16.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CLP1_P PF16575.5 CAM42250.1 - 0.011 15.5 0.1 1.4 8.6 0.0 2.6 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop APS_kinase PF01583.20 CAM42250.1 - 0.012 15.5 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase ATP_bind_1 PF03029.17 CAM42250.1 - 0.017 14.9 0.1 0.11 12.2 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ResIII PF04851.15 CAM42250.1 - 0.027 14.5 0.6 2.2 8.3 0.1 2.4 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit SRPRB PF09439.10 CAM42250.1 - 0.029 13.8 0.7 2.7 7.4 0.7 2.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 CAM42250.1 - 0.032 13.9 0.4 0.11 12.2 0.1 2.0 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 CAM42250.1 - 0.039 13.3 0.3 0.38 10.0 0.0 2.4 2 0 0 2 2 2 0 KaiC MobB PF03205.14 CAM42250.1 - 0.054 13.4 0.1 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SWI2_SNF2 PF18766.1 CAM42250.1 - 0.071 12.8 0.6 1.3 8.6 0.0 2.3 1 1 1 2 2 2 0 SWI2/SNF2 ATPase AAA_31 PF13614.6 CAM42250.1 - 0.074 13.0 1.1 2.4 8.0 0.0 2.8 2 1 1 3 3 2 0 AAA domain AAA_19 PF13245.6 CAM42250.1 - 0.11 12.8 0.8 0.3 11.4 0.1 2.0 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 CAM42250.1 - 0.14 12.2 0.3 0.43 10.6 0.0 1.9 2 0 0 2 2 2 0 Dynamin family NTPase_1 PF03266.15 CAM42250.1 - 0.17 11.8 1.4 4.7 7.1 1.4 2.5 1 1 0 1 1 1 0 NTPase AAA PF00004.29 CAM42250.1 - 0.84 10.1 4.0 2.9 8.3 0.2 3.6 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) HAD_SAK_2 PF18143.1 CAM42252.1 - 9.8e-33 113.4 0.1 1.5e-31 109.6 0.0 2.1 2 0 0 2 2 2 1 HAD domain in Swiss Army Knife RNA repair proteins Val_tRNA-synt_C PF10458.9 CAM42252.1 - 0.059 13.7 6.9 0.44 10.9 0.1 2.9 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm CENP-F_leu_zip PF10473.9 CAM42252.1 - 0.25 11.4 6.1 0.069 13.2 1.9 1.9 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SNF2_N PF00176.23 CAM42253.1 - 1.1e-57 195.3 0.0 1.8e-57 194.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CAM42253.1 - 2.8e-16 59.8 0.0 9.8e-16 58.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAM42253.1 - 4e-10 39.9 0.0 7.7e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CAM42253.1 - 3.8e-08 33.3 0.0 7.7e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 CAM42253.1 - 1.4e-06 27.7 0.0 2.5e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Rad54_N PF08658.10 CAM42253.1 - 0.037 14.2 0.0 0.098 12.8 0.0 1.7 1 0 0 1 1 1 0 Rad54 N terminal Malic_M PF03949.15 CAM42254.2 - 8.5e-84 280.8 0.1 1.2e-83 280.4 0.1 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 CAM42254.2 - 2.4e-66 223.0 0.0 1.6e-65 220.3 0.0 2.0 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain RuBisCO_large PF00016.20 CAM42254.2 - 0.034 13.3 0.1 0.059 12.6 0.1 1.3 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain DUF3385 PF11865.8 CAM42254.2 - 0.088 12.7 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) Malic_M PF03949.15 CAM42255.2 - 2e-83 279.6 0.0 1e-82 277.3 0.0 1.9 2 0 0 2 2 2 1 Malic enzyme, NAD binding domain malic PF00390.19 CAM42255.2 - 6.1e-70 234.7 0.0 9e-70 234.2 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Bac_luciferase PF00296.20 CAM42255.2 - 0.16 11.4 0.0 0.4 10.0 0.0 1.5 1 1 0 1 1 1 0 Luciferase-like monooxygenase 2-oxogl_dehyd_N PF16078.5 CAM42257.1 - 0.17 11.5 0.2 0.64 9.7 0.0 2.1 2 0 0 2 2 2 0 2-oxoglutarate dehydrogenase N-terminus PTS_2-RNA PF01885.16 CAM42259.2 - 6.7e-55 185.9 0.0 1e-54 185.4 0.0 1.2 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family RNase_T PF00929.24 CAM42259.2 - 7.2e-20 72.2 0.0 1.2e-19 71.5 0.0 1.4 1 0 0 1 1 1 1 Exonuclease Syja_N PF02383.18 CAM42260.2 - 4e-56 190.7 0.0 6.5e-56 190.0 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain DUF547 PF04784.14 CAM42260.2 - 0.0031 17.5 0.0 0.0071 16.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF547 PPR_long PF17177.4 CAM42261.1 - 0.074 12.4 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP EMP24_GP25L PF01105.24 CAM42263.1 - 6.3e-17 62.1 0.0 7.6e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF779 PF05610.11 CAM42263.1 - 0.038 14.3 0.0 6.6 7.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF779) DUF5564 PF17719.1 CAM42263.1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5564) DUF202 PF02656.15 CAM42263.1 - 0.67 10.4 3.4 5.7 7.5 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DNA_pol_A PF00476.20 CAM42265.1 - 6.3e-54 183.5 0.0 2.3e-53 181.6 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase family A MCM PF00493.23 CAM42267.1 - 4.1e-87 291.0 0.0 6.4e-87 290.3 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CAM42267.1 - 3.4e-33 114.2 0.2 6.2e-33 113.3 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CAM42267.1 - 1.3e-23 83.2 2.0 2.4e-23 82.3 0.7 2.2 2 1 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 CAM42267.1 - 7.2e-10 39.4 0.0 2.1e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CAM42267.1 - 3.5e-07 29.8 0.0 6.6e-06 25.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CAM42267.1 - 0.00033 20.5 0.0 0.001 19.0 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CAM42267.1 - 0.00069 19.6 0.0 0.0016 18.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) PUA PF01472.20 CAM42267.1 - 0.015 15.3 1.3 3.7 7.6 0.2 2.7 2 0 0 2 2 2 0 PUA domain Sigma54_activat PF00158.26 CAM42267.1 - 0.056 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Keratin_B2 PF01500.17 CAM42267.1 - 4.5 7.2 13.8 0.9 9.5 5.2 2.8 3 0 0 3 3 3 0 Keratin, high sulfur B2 protein MTS PF05175.14 CAM42268.1 - 0.0009 18.8 0.0 0.02 14.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 CAM42268.1 - 0.0057 17.3 0.0 0.029 15.1 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain ANAPC4_WD40 PF12894.7 CAM42269.1 - 0.087 13.1 0.0 0.28 11.5 0.0 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain EH_Signature PF15611.6 CAM42269.1 - 0.12 11.7 2.2 0.25 10.7 2.2 1.4 1 1 0 1 1 1 0 EH_Signature domain RabGAP-TBC PF00566.18 CAM42271.1 - 5.6e-10 39.2 2.8 1.7e-09 37.6 3.1 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain RFC1 PF08519.12 CAM42275.1 - 3.6e-42 144.2 0.0 7.3e-42 143.2 0.0 1.5 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain AAA PF00004.29 CAM42275.1 - 4.1e-12 46.7 0.0 1e-11 45.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CAM42275.1 - 2e-08 34.4 0.0 3.8e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain Zeta_toxin PF06414.12 CAM42275.1 - 6.4e-05 22.3 0.0 0.0002 20.7 0.0 1.8 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 CAM42275.1 - 0.0005 20.3 0.0 0.0015 18.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CAM42275.1 - 0.00078 19.5 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CAM42275.1 - 0.001 18.9 0.0 0.0025 17.6 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CAM42275.1 - 0.0014 19.0 0.1 0.0048 17.3 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CAM42275.1 - 0.0027 17.7 0.0 0.0055 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 CAM42275.1 - 0.0029 17.8 0.5 0.33 11.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CAM42275.1 - 0.028 14.8 0.0 0.077 13.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 CAM42275.1 - 0.034 14.7 0.0 0.091 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CAM42275.1 - 0.036 14.2 0.7 0.089 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CAM42275.1 - 0.049 13.1 0.0 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 CAM42275.1 - 0.049 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_assoc_2 PF16193.5 CAM42275.1 - 0.08 13.3 0.0 0.27 11.6 0.0 2.0 1 0 0 1 1 1 0 AAA C-terminal domain AAA_6 PF12774.7 CAM42275.1 - 0.089 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_19 PF13245.6 CAM42275.1 - 0.28 11.5 2.4 0.36 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain PAP1 PF08601.10 CAM42275.1 - 2.3 7.9 20.8 3.9 7.1 20.8 1.4 1 0 0 1 1 1 0 Transcription factor PAP1 Mnd1 PF03962.15 CAM42277.1 - 3.4e-16 59.3 0.0 8.4e-16 58.0 0.0 1.7 2 0 0 2 2 2 1 Mnd1 HTH domain LZ3wCH PF18517.1 CAM42277.1 - 0.00014 21.9 0.0 0.00036 20.6 0.0 1.8 1 0 0 1 1 1 1 Leucine zipper with capping helix domain FUSC PF04632.12 CAM42277.1 - 0.58 8.6 7.3 0.83 8.1 7.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Kelch_6 PF13964.6 CAM42278.1 - 5.7e-15 55.0 1.9 0.00033 20.8 0.0 3.9 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.6 CAM42278.1 - 1.1e-12 47.7 0.1 1e-05 25.5 0.0 3.7 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.25 CAM42278.1 - 3.8e-09 36.0 6.5 0.0002 20.9 0.0 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 CAM42278.1 - 5.6e-09 35.8 0.1 0.0014 18.6 0.0 3.2 2 0 0 2 2 2 2 Kelch motif F-box-like PF12937.7 CAM42278.1 - 4.1e-05 23.4 0.1 9.7e-05 22.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like Kelch_3 PF13415.6 CAM42278.1 - 4.1e-05 23.7 0.9 1.7 9.0 0.3 3.9 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.15 CAM42278.1 - 8.8e-05 22.3 0.0 0.082 12.9 0.0 3.6 3 0 0 3 3 3 1 Kelch motif F-box PF00646.33 CAM42278.1 - 0.00011 22.0 0.0 0.00033 20.5 0.0 1.8 1 0 0 1 1 1 1 F-box domain FAM75 PF14650.6 CAM42278.1 - 0.0044 16.6 1.8 0.01 15.4 1.8 1.6 1 0 0 1 1 1 1 FAM75 family LRR_4 PF12799.7 CAM42279.1 - 1.4e-17 63.5 23.7 3.5e-07 30.4 0.7 3.7 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CAM42279.1 - 3.5e-10 39.7 0.7 3.9e-08 33.0 0.4 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 CAM42279.1 - 1.2e-09 37.7 7.2 1.2e-06 28.2 0.3 3.0 2 1 2 4 4 4 3 Leucine rich repeat FNIP PF05725.12 CAM42279.1 - 0.25 11.5 1.5 0.41 10.9 0.2 1.9 2 0 0 2 2 2 0 FNIP Repeat LRR_1 PF00560.33 CAM42279.1 - 0.26 12.0 5.9 13 6.8 0.4 3.4 2 2 0 2 2 2 0 Leucine Rich Repeat SNF2_N PF00176.23 CAM42281.1 - 5.3e-35 120.8 0.0 1.9e-34 118.9 0.0 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CAM42281.1 - 9e-14 51.8 0.0 3.1e-12 46.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAM42281.1 - 0.0026 17.8 0.0 0.11 12.5 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 CAM42281.1 - 0.016 14.9 0.1 0.05 13.3 0.0 1.8 2 0 0 2 2 2 0 SWI2/SNF2 ATPase CAMSAP_CC1 PF17095.5 CAM42281.1 - 0.055 13.3 5.7 0.15 11.9 5.7 1.7 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin AKAP7_NLS PF10469.9 CAM42282.1 - 1.6e-17 64.1 0.0 4.5e-17 62.6 0.0 1.7 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain ADK_lid PF05191.14 CAM42282.1 - 0.056 13.4 0.0 2.2 8.3 0.0 2.8 2 0 0 2 2 2 0 Adenylate kinase, active site lid C1_2 PF03107.16 CAM42282.1 - 0.081 13.2 2.1 0.094 13.0 0.4 1.9 2 0 0 2 2 2 0 C1 domain zinc_ribbon_2 PF13240.6 CAM42282.1 - 0.55 10.0 2.3 1.1 9.1 2.3 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Hormone_3 PF00159.18 CAM42283.2 - 0.22 11.6 0.5 23 5.2 0.1 2.8 2 0 0 2 2 2 0 Pancreatic hormone peptide DnaJ PF00226.31 CAM42284.1 - 5.2e-14 52.1 0.1 2.1e-13 50.2 0.0 2.1 3 0 0 3 3 3 1 DnaJ domain HA2 PF04408.23 CAM42286.1 - 4.2e-12 46.3 0.3 1.7e-11 44.3 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CAM42286.1 - 1.5e-10 41.3 0.0 3.2e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CAM42286.1 - 1e-09 38.7 0.1 2.9e-09 37.2 0.1 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CAM42286.1 - 8.9e-06 25.6 0.1 2e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CAM42286.1 - 0.0048 17.2 0.7 0.036 14.4 0.7 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CAM42286.1 - 0.0049 16.6 0.1 0.012 15.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CAM42286.1 - 0.0052 17.1 0.1 0.014 15.7 0.1 1.7 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CAM42286.1 - 0.15 11.4 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 KaiC FH2 PF02181.23 CAM42287.1 - 2.9e-52 178.1 0.0 3.8e-52 177.7 0.0 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain PTEN_C2 PF10409.9 CAM42287.1 - 0.0034 17.1 0.1 0.0088 15.8 0.0 1.7 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein Skp1_POZ PF03931.15 CAM42287.1 - 0.19 11.9 0.0 0.44 10.8 0.0 1.6 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain SOAR PF16533.5 CAM42287.1 - 0.43 10.6 1.8 50 3.9 0.0 3.2 3 0 0 3 3 3 0 STIM1 Orai1-activating region APG6_N PF17675.1 CAM42290.1 - 0.0054 17.3 10.4 0.0054 17.3 10.4 6.8 5 1 1 6 6 6 2 Apg6 coiled-coil region CC2-LZ PF16516.5 CAM42290.1 - 0.016 15.5 7.0 0.016 15.5 7.0 8.1 6 3 2 8 8 8 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF573 PF04504.14 CAM42290.1 - 3.1 8.5 7.0 0.84 10.3 0.9 3.3 2 1 1 3 3 3 0 Protein of unknown function, DUF573 RNA_pol PF00940.19 CAM42292.1 - 2.9e-133 444.7 0.0 4.8e-133 444.0 0.0 1.4 1 0 0 1 1 1 1 DNA-dependent RNA polymerase Nore1-SARAH PF16517.5 CAM42293.1 - 0.67 9.9 3.9 20 5.2 0.1 2.8 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain GTP-bdg_M PF16360.5 CAM42293.1 - 1.9 9.2 16.8 1 10.0 0.5 4.1 3 1 0 3 3 3 0 GTP-binding GTPase Middle Region Adaptin_binding PF10199.9 CAM42294.1 - 8.2e-05 23.2 0.0 0.059 14.0 0.0 2.9 3 1 0 3 3 3 2 Alpha and gamma adaptin binding protein p34 SURF6 PF04935.12 CAM42295.1 - 2e-15 57.2 15.3 2.3e-15 56.9 11.2 2.0 1 1 1 2 2 2 1 Surfeit locus protein 6 Phage-MuB_C PF09077.11 CAM42295.1 - 0.015 15.2 1.5 0.058 13.3 1.5 2.1 1 1 0 1 1 1 0 Mu B transposition protein, C terminal Bax1-I PF01027.20 CAM42296.1 - 5.4e-41 140.7 19.4 8.2e-41 140.1 19.4 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 CAM42296.1 - 9.8e-09 35.1 8.1 1.5e-08 34.5 8.1 1.3 1 0 0 1 1 1 1 Bax inhibitor 1 like YL1 PF05764.13 CAM42297.1 - 1.7e-10 41.4 24.8 2.3e-09 37.7 22.6 2.0 1 1 1 2 2 2 2 YL1 nuclear protein SUI1 PF01253.22 CAM42298.1 - 2.6e-21 75.9 0.2 3.3e-21 75.6 0.2 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 PHD PF00628.29 CAM42300.1 - 6.7e-07 29.1 7.4 6.7e-07 29.1 7.4 1.7 2 0 0 2 2 2 1 PHD-finger Acetyltransf_7 PF13508.7 CAM42300.1 - 1e-05 25.9 0.0 4.5e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain PHD_4 PF16866.5 CAM42300.1 - 0.00076 19.5 2.8 0.00076 19.5 2.8 2.3 2 0 0 2 2 2 1 PHD-finger Acetyltransf_10 PF13673.7 CAM42300.1 - 0.0067 16.4 0.2 0.64 10.0 0.2 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Amastin PF07344.11 CAM42302.1 - 1.9e-33 115.5 13.8 2.3e-33 115.2 13.8 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Amastin PF07344.11 CAM42303.1 - 3.7e-41 140.5 14.1 4.8e-41 140.2 14.1 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF1345 PF07077.11 CAM42303.1 - 0.0045 16.7 0.7 0.0045 16.7 0.7 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1345) SUR7 PF06687.12 CAM42303.1 - 2.7 7.6 24.0 0.11 12.0 13.0 2.1 1 1 0 2 2 2 0 SUR7/PalI family Amastin PF07344.11 CAM42304.1 - 1.7e-41 141.6 15.1 2e-41 141.4 15.1 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein LRR_6 PF13516.6 CAM42305.1 - 0.001 18.9 1.4 2 8.6 0.0 3.4 3 0 0 3 3 3 2 Leucine Rich repeat EF-hand_6 PF13405.6 CAM42305.1 - 0.032 14.2 0.1 10 6.4 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.32 CAM42305.1 - 0.13 11.9 1.3 13 5.6 0.1 3.0 3 0 0 3 3 3 0 EF hand Clat_adaptor_s PF01217.20 CAM42307.1 - 3.7e-44 150.1 0.6 4.3e-44 149.9 0.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MRG PF05712.13 CAM42307.1 - 0.038 13.3 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 MRG RecQ_Zn_bind PF16124.5 CAM42308.2 - 8.3e-16 58.5 0.1 2.5e-15 56.9 0.1 1.9 1 0 0 1 1 1 1 RecQ zinc-binding DEAD PF00270.29 CAM42308.2 - 5.6e-15 55.5 0.0 2.3e-14 53.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAM42308.2 - 1.6e-13 50.9 0.0 5.1e-12 46.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HRDC PF00570.23 CAM42308.2 - 1.9e-05 24.5 0.0 3.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 HRDC domain Choline_kin_N PF04428.14 CAM42308.2 - 0.074 12.7 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Choline kinase N terminus GreA_GreB_N PF03449.15 CAM42308.2 - 0.25 11.5 1.1 0.67 10.2 1.1 1.7 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal ERCC4 PF02732.15 CAM42309.2 - 2e-09 37.8 0.0 3.9e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain SAP PF02037.27 CAM42309.2 - 9.8e-05 22.0 0.3 9.8e-05 22.0 0.3 2.0 2 0 0 2 2 2 1 SAP domain TCTP PF00838.17 CAM42310.1 - 8e-45 153.2 1.2 9e-45 153.0 1.2 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein UPF0262 PF06793.12 CAM42310.1 - 0.11 12.6 0.1 0.14 12.2 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0262) DUF932 PF06067.11 CAM42310.1 - 0.12 12.1 0.2 0.19 11.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF932) WD40 PF00400.32 CAM42311.1 - 6.2e-08 33.2 4.1 0.0028 18.4 0.2 4.9 4 0 0 4 4 4 3 WD domain, G-beta repeat START PF01852.19 CAM42312.2 - 0.0079 15.6 0.0 0.71 9.2 0.0 2.9 3 0 0 3 3 3 1 START domain CALM_bind PF16025.5 CAM42312.2 - 0.086 13.3 0.2 0.19 12.2 0.2 1.6 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding WD40 PF00400.32 CAM42313.1 - 0.046 14.6 0.0 40 5.3 0.0 4.9 4 0 0 4 4 4 0 WD domain, G-beta repeat PGA2 PF07543.12 CAM42313.1 - 0.24 11.4 0.3 9.2 6.2 0.1 2.4 2 0 0 2 2 2 0 Protein trafficking PGA2 Pkinase PF00069.25 CAM42316.1 - 1.1e-64 218.3 0.0 1.4e-64 218.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM42316.1 - 1.1e-40 139.6 0.0 1.6e-40 139.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAM42316.1 - 1e-05 24.5 0.0 1.9e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CAM42316.1 - 2.6e-05 23.7 0.0 0.00014 21.2 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CAM42316.1 - 0.0087 15.7 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CAM42316.1 - 0.011 15.7 0.1 0.33 10.8 0.1 2.7 1 1 2 3 3 3 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CAM42316.1 - 0.24 10.3 0.0 0.5 9.2 0.0 1.3 1 1 0 1 1 1 0 Haspin like kinase domain HpcH_HpaI PF03328.14 CAM42317.2 - 6.6e-22 77.7 0.0 7.7e-19 67.7 0.0 2.8 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 CAM42317.2 - 1.3e-13 50.8 0.0 8.4e-07 28.5 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold DUF563 PF04577.14 CAM42318.2 - 3.8e-11 43.5 0.1 9.4e-11 42.2 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF563) DUF4192 PF13830.6 CAM42318.2 - 0.081 13.0 0.5 0.17 11.9 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Kinesin PF00225.23 CAM42320.1 - 1.1e-55 188.9 0.0 6.1e-39 133.9 0.0 2.2 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 CAM42320.1 - 5.3e-11 42.7 0.0 1e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding Mlh1_C PF16413.5 CAM42321.1 - 1e-31 110.3 0.0 2.6e-11 43.4 0.0 3.2 3 0 0 3 3 3 3 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 CAM42321.1 - 2.3e-23 82.2 0.0 4.5e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CAM42321.1 - 1.7e-10 40.8 0.1 2.1e-09 37.3 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CAM42321.1 - 3.7e-05 24.2 0.0 8.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Insulin_TMD PF17870.1 CAM42322.2 - 0.11 12.6 0.6 0.22 11.6 0.6 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment BicD PF09730.9 CAM42323.2 - 0.023 13.1 14.5 0.4 9.0 8.0 2.0 1 1 1 2 2 2 0 Microtubule-associated protein Bicaudal-D Atg14 PF10186.9 CAM42323.2 - 0.033 13.3 11.1 0.045 12.8 11.1 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SlyX PF04102.12 CAM42323.2 - 0.22 12.2 14.4 1.5 9.5 1.8 3.5 2 1 0 3 3 3 0 SlyX TMF_TATA_bd PF12325.8 CAM42323.2 - 0.46 10.7 16.2 0.91 9.8 12.3 2.3 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Borrelia_P83 PF05262.11 CAM42323.2 - 1.9 6.9 13.8 2.4 6.6 13.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF641 PF04859.12 CAM42323.2 - 2.2 8.6 16.0 1.1 9.6 8.0 2.8 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) DUF16 PF01519.16 CAM42323.2 - 2.9 8.4 9.8 15 6.1 7.1 2.7 1 1 2 3 3 3 0 Protein of unknown function DUF16 UPF0242 PF06785.11 CAM42323.2 - 3.2 7.8 17.0 9.9 6.2 17.0 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus LMBR1 PF04791.16 CAM42323.2 - 7 5.4 5.4 7.9 5.3 5.4 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein V_ATPase_I PF01496.19 CAM42323.2 - 7.3 4.4 6.1 8.4 4.2 6.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EF-hand_7 PF13499.6 CAM42324.1 - 4.5e-22 78.3 5.8 6.6e-13 48.9 0.5 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CAM42324.1 - 7.1e-19 66.1 5.2 0.00088 19.0 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 CAM42324.1 - 9.4e-19 65.5 7.0 0.0001 21.6 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 CAM42324.1 - 5.3e-14 51.0 8.4 6.6e-05 22.2 0.1 4.3 4 0 0 4 4 4 4 EF hand zf-C3HC4_3 PF13920.6 CAM42324.1 - 4.2e-11 42.5 6.3 4.2e-11 42.5 6.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) EF-hand_8 PF13833.6 CAM42324.1 - 1.5e-09 37.5 6.0 0.0016 18.2 0.2 3.5 3 1 0 3 3 3 3 EF-hand domain pair zf-C3HC4_2 PF13923.6 CAM42324.1 - 2.3e-09 37.0 10.1 4.9e-09 35.9 10.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CAM42324.1 - 3.3e-08 33.4 2.7 3.3e-08 33.4 2.7 2.5 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CAM42324.1 - 4.2e-08 32.9 7.5 1.3e-07 31.4 7.6 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CAM42324.1 - 5.3e-08 32.7 7.2 5.3e-08 32.7 7.2 1.7 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CAM42324.1 - 1.7e-06 28.3 8.8 1.7e-06 28.3 8.8 1.8 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 CAM42324.1 - 2.9e-06 27.0 9.1 2.9e-06 27.0 9.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SPARC_Ca_bdg PF10591.9 CAM42324.1 - 3.6e-06 27.3 0.0 0.001 19.3 0.0 2.4 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region zf-RING_6 PF14835.6 CAM42324.1 - 0.00013 21.8 4.1 0.00028 20.7 4.1 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 CAM42324.1 - 0.0011 19.1 4.8 0.0011 19.1 4.8 2.5 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 CAM42324.1 - 0.06 13.1 6.4 0.038 13.7 3.3 2.2 2 0 0 2 2 2 0 RING-like zinc finger EF-hand_10 PF14788.6 CAM42324.1 - 0.1 12.5 0.3 50 3.9 0.0 3.4 3 1 1 4 4 4 0 EF hand zf-RING_10 PF16685.5 CAM42324.1 - 2.3 8.4 10.9 7.5 6.8 10.8 1.9 1 1 1 2 2 2 0 zinc RING finger of MSL2 DZR PF12773.7 CAM42324.1 - 7.4 6.7 13.2 86 3.3 12.4 2.5 1 1 0 1 1 1 0 Double zinc ribbon EF-hand_7 PF13499.6 CAM42325.1 - 4.2e-22 78.4 5.6 6.7e-13 48.9 0.4 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CAM42325.1 - 7.4e-19 66.0 5.2 0.00088 19.0 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 CAM42325.1 - 8.2e-19 65.7 6.8 0.0001 21.6 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 CAM42325.1 - 5.2e-14 51.0 8.4 6.6e-05 22.2 0.1 4.3 4 0 0 4 4 4 4 EF hand zf-C3HC4_3 PF13920.6 CAM42325.1 - 4.2e-11 42.5 6.3 4.2e-11 42.5 6.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) EF-hand_8 PF13833.6 CAM42325.1 - 1.5e-09 37.5 6.0 0.0016 18.2 0.2 3.5 3 1 0 3 3 3 3 EF-hand domain pair zf-C3HC4_2 PF13923.6 CAM42325.1 - 2.3e-09 37.0 10.1 4.9e-09 35.9 10.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CAM42325.1 - 3.3e-08 33.4 2.7 3.3e-08 33.4 2.7 2.5 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CAM42325.1 - 4.2e-08 32.9 7.5 1.3e-07 31.4 7.6 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CAM42325.1 - 5.3e-08 32.7 7.2 5.3e-08 32.7 7.2 1.7 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CAM42325.1 - 1.7e-06 28.3 8.8 1.7e-06 28.3 8.8 1.8 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 CAM42325.1 - 2.9e-06 27.0 9.1 2.9e-06 27.0 9.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SPARC_Ca_bdg PF10591.9 CAM42325.1 - 3.6e-06 27.3 0.0 0.001 19.3 0.0 2.4 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region zf-RING_6 PF14835.6 CAM42325.1 - 0.00013 21.7 4.1 0.00028 20.7 4.1 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 CAM42325.1 - 0.0011 19.1 4.8 0.0011 19.1 4.8 2.5 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 CAM42325.1 - 0.06 13.1 6.4 0.038 13.7 3.3 2.2 2 0 0 2 2 2 0 RING-like zinc finger EF-hand_10 PF14788.6 CAM42325.1 - 0.1 12.5 0.3 50 3.9 0.0 3.3 3 1 1 4 4 4 0 EF hand zf-RING_10 PF16685.5 CAM42325.1 - 2.3 8.4 10.9 7.5 6.8 10.8 1.9 1 1 1 2 2 2 0 zinc RING finger of MSL2 DZR PF12773.7 CAM42325.1 - 7.4 6.7 13.2 86 3.3 12.4 2.5 1 1 0 1 1 1 0 Double zinc ribbon Hist_deacetyl PF00850.19 CAM42326.1 - 4.8e-72 243.0 0.1 5.8e-72 242.8 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Dymeclin PF09742.9 CAM42327.1 - 1.2e-55 189.2 0.0 1.5e-55 188.9 0.0 1.1 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 CAM42327.1 - 7.9e-27 93.8 6.3 1.4e-14 53.2 2.8 4.2 4 1 0 4 4 4 3 High-temperature-induced dauer-formation protein IQ PF00612.27 CAM42328.1 - 2.4e-06 26.8 39.1 0.0079 15.9 0.4 6.9 6 1 0 6 6 6 5 IQ calmodulin-binding motif HTH_37 PF13744.6 CAM42328.1 - 0.59 10.1 4.0 0.65 10.0 0.6 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain GTP_EFTU PF00009.27 CAM42329.1 - 6.6e-24 84.5 1.1 5.1e-22 78.4 1.3 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CAM42329.1 - 8.3e-12 45.2 0.0 2e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 CAM42329.1 - 0.00011 21.9 0.0 0.00068 19.4 0.0 2.2 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 CAM42329.1 - 0.0011 19.0 0.1 0.097 12.6 0.4 2.7 2 0 0 2 2 2 1 RsgA GTPase IF-2 PF11987.8 CAM42329.1 - 0.0012 19.0 0.0 0.0027 17.8 0.0 1.5 1 0 0 1 1 1 1 Translation-initiation factor 2 Dynamin_N PF00350.23 CAM42329.1 - 0.0071 16.4 1.0 0.14 12.2 0.0 3.0 2 1 1 3 3 3 1 Dynamin family Roc PF08477.13 CAM42329.1 - 0.011 16.0 0.0 0.031 14.5 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 CAM42329.1 - 0.019 14.6 3.2 0.12 12.0 0.5 3.0 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 CAM42329.1 - 0.033 13.7 0.2 0.13 11.7 0.2 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF1484 PF07363.11 CAM42329.1 - 0.038 15.0 0.2 0.1 13.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1484) TniB PF05621.11 CAM42329.1 - 0.082 12.3 0.0 0.22 10.9 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein SRPRB PF09439.10 CAM42329.1 - 0.11 11.9 0.0 0.33 10.4 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit APO_RNA-bind PF05634.11 CAM42329.1 - 0.12 11.7 1.3 7.4 5.9 0.1 2.8 3 0 0 3 3 3 0 APO RNA-binding TRAPP PF04051.16 CAM42331.1 - 1.1e-06 28.4 0.0 1.3e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Pro_isomerase PF00160.21 CAM42332.1 - 2.3e-18 66.9 0.0 3.2e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD BLUF PF04940.12 CAM42333.1 - 0.039 14.1 0.0 0.096 12.8 0.0 1.7 1 0 0 1 1 1 0 Sensors of blue-light using FAD Amastin PF07344.11 CAM42334.1 - 5.2e-45 153.1 13.5 6e-45 152.9 13.5 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein SUR7 PF06687.12 CAM42334.1 - 0.023 14.4 18.1 0.016 14.8 12.0 2.1 2 0 0 2 2 2 0 SUR7/PalI family Amastin PF07344.11 CAM42335.1 - 1.8e-41 141.6 15.0 2.1e-41 141.4 15.0 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Amastin PF07344.11 CAM42336.1 - 1.8e-32 112.4 12.7 2.3e-32 112.0 12.7 1.2 1 0 0 1 1 1 1 Amastin surface glycoprotein Peptidase_C7 PF01830.18 CAM42336.1 - 0.041 13.3 0.1 0.066 12.6 0.1 1.3 1 0 0 1 1 1 0 Peptidase C7 family WASH-7_mid PF14744.6 CAM42337.1 - 4.7e-128 427.1 0.5 7.8e-128 426.4 0.5 1.3 1 0 0 1 1 1 1 WASH complex subunit 7 WASH-7_C PF14746.6 CAM42337.1 - 3.3e-47 160.4 0.2 9.9e-47 158.9 0.2 1.9 1 0 0 1 1 1 1 WASH complex subunit 7, C-terminal WASH-7_N PF14745.6 CAM42337.1 - 3.2e-25 88.7 0.0 5.3e-15 54.9 0.0 2.3 2 0 0 2 2 2 2 WASH complex subunit 7, N-terminal DnaJ PF00226.31 CAM42338.1 - 2.3e-10 40.4 0.0 4.9e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain CCG PF02754.16 CAM42338.1 - 0.021 15.0 0.1 0.086 13.1 0.0 2.0 2 0 0 2 2 2 0 Cysteine-rich domain Rhomboid PF01694.22 CAM42339.1 - 0.013 15.5 1.2 0.026 14.5 1.2 1.5 1 0 0 1 1 1 0 Rhomboid family UBA PF00627.31 CAM42339.1 - 0.056 13.4 0.3 0.1 12.5 0.3 1.5 1 0 0 1 1 1 0 UBA/TS-N domain ketoacyl-synt PF00109.26 CAM42341.1 - 0.1 12.1 0.5 0.11 12.0 0.5 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain DNA_Packaging PF11053.8 CAM42341.1 - 0.17 11.7 1.1 5.7 6.8 0.2 2.0 2 0 0 2 2 2 0 Terminase DNA packaging enzyme zf-rbx1 PF12678.7 CAM42342.1 - 1.3e-20 73.5 12.9 1.8e-20 73.0 12.9 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CAM42342.1 - 5.2e-12 45.7 10.0 7.1e-12 45.2 9.4 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 CAM42342.1 - 1.5e-09 38.0 5.7 1.5e-09 38.0 5.7 2.2 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 CAM42342.1 - 3.4e-06 26.8 11.0 5.2e-05 23.0 11.0 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CAM42342.1 - 0.00017 21.4 8.2 0.00017 21.4 8.2 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CAM42342.1 - 0.00033 20.5 3.6 0.00033 20.5 3.6 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CAM42342.1 - 0.00046 19.8 15.5 0.028 14.0 2.1 2.2 1 1 1 2 2 2 2 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 CAM42342.1 - 0.0015 18.2 13.1 0.32 10.8 13.1 2.4 1 1 0 1 1 1 1 RING-like zinc finger FANCL_C PF11793.8 CAM42342.1 - 0.058 13.6 10.0 0.12 12.6 10.0 1.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.6 CAM42342.1 - 0.13 12.3 13.7 0.76 9.9 13.7 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 CAM42342.1 - 0.14 12.1 12.2 0.95 9.5 12.2 2.0 1 1 0 1 1 1 0 zinc-RING finger domain GST_N_4 PF17172.4 CAM42343.1 - 1.2e-13 51.7 0.0 2.3e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 CAM42343.1 - 1.6e-06 28.5 0.0 3.3e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 CAM42343.1 - 3.4e-05 23.6 0.2 0.00018 21.2 0.1 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CAM42343.1 - 0.0025 17.8 0.0 0.0065 16.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PfaD_N PF18328.1 CAM42343.1 - 0.062 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Fatty acid synthase subunit PfaD N-terminal domain FAD_binding_2 PF00890.24 CAM42344.1 - 2.9e-117 392.3 2.6 2.8e-116 389.0 1.4 2.0 2 0 0 2 2 2 1 FAD binding domain Succ_DH_flav_C PF02910.20 CAM42344.1 - 2.3e-41 140.8 0.9 3.2e-41 140.3 0.9 1.2 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 CAM42344.1 - 0.00037 19.8 0.1 0.00099 18.4 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CAM42344.1 - 0.0013 18.0 0.1 0.17 11.1 0.1 2.3 2 0 0 2 2 2 2 Thi4 family DAO PF01266.24 CAM42344.1 - 0.002 17.8 0.5 0.019 14.6 0.5 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CAM42344.1 - 0.026 13.3 0.1 0.044 12.5 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 CAM42344.1 - 0.085 11.9 4.0 0.11 11.5 2.4 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 CAM42344.1 - 0.1 11.6 1.6 1.7 7.6 0.5 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 CAM42344.1 - 0.11 11.8 2.3 0.62 9.2 0.3 2.3 2 0 0 2 2 2 0 FAD binding domain NAD_binding_4 PF07993.12 CAM42345.1 - 1.7e-65 220.8 0.0 2.3e-65 220.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.19 CAM42345.1 - 1.1e-11 44.8 0.1 2.4e-11 43.7 0.1 1.6 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 CAM42345.1 - 2.2e-05 24.1 0.3 7.5e-05 22.3 0.1 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 CAM42345.1 - 0.0012 18.0 0.0 0.079 12.0 0.0 2.8 3 0 0 3 3 3 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 CAM42345.1 - 0.004 16.6 0.1 0.38 10.1 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 CAM42345.1 - 0.027 13.6 0.3 1.2 8.2 0.3 2.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 CAM42345.1 - 0.11 12.9 0.0 0.27 11.7 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF4515 PF14988.6 CAM42346.1 - 0.62 9.9 48.7 0.49 10.2 6.1 3.3 1 1 1 3 3 3 0 Domain of unknown function (DUF4515) TMF_TATA_bd PF12325.8 CAM42346.1 - 2.6 8.3 41.4 0.024 14.9 8.6 4.6 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding SpoU_methylase PF00588.19 CAM42347.1 - 6e-15 55.7 0.0 3.4e-13 50.0 0.0 2.5 1 1 0 1 1 1 1 SpoU rRNA Methylase family Ssl1 PF04056.14 CAM42349.1 - 1.3e-17 64.2 0.1 3.3e-08 33.6 0.0 2.2 1 1 0 2 2 2 2 Ssl1-like VWA_2 PF13519.6 CAM42349.1 - 1.5e-08 35.2 0.0 3e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Rubredoxin_2 PF18073.1 CAM42349.1 - 0.043 13.5 8.0 1.1 9.0 0.5 3.5 3 0 0 3 3 3 0 Rubredoxin metal binding domain EBV-NA3 PF05009.12 CAM42349.1 - 0.06 12.9 0.0 0.093 12.2 0.0 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) C1_4 PF07975.12 CAM42349.1 - 0.13 12.6 3.8 1.8 8.9 0.6 3.5 3 0 0 3 3 3 0 TFIIH C1-like domain DZR PF12773.7 CAM42349.1 - 2.4 8.3 9.7 5.1e+02 0.8 9.7 2.6 1 1 0 1 1 1 0 Double zinc ribbon SET PF00856.28 CAM42350.1 - 7.8e-10 39.4 0.2 1.5e-09 38.4 0.2 1.5 1 1 0 1 1 1 1 SET domain TPR_1 PF00515.28 CAM42350.1 - 0.0012 18.6 0.8 0.0012 18.6 0.8 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat zf-tcix PF14952.6 CAM42350.1 - 0.0027 17.3 1.5 0.0027 17.3 1.5 2.7 4 0 0 4 4 4 1 Putative treble-clef, zinc-finger, Zn-binding TPR_2 PF07719.17 CAM42350.1 - 0.05 13.7 0.4 0.05 13.7 0.4 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Romo1 PF10247.9 CAM42351.1 - 0.36 11.2 3.3 4.4 7.7 0.1 2.6 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Ribosomal_S21 PF01165.20 CAM42351.1 - 1.9 8.2 5.4 0.44 10.3 0.6 2.3 2 0 0 2 2 2 0 Ribosomal protein S21 UQ_con PF00179.26 CAM42352.1 - 2e-18 66.4 0.0 2.7e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CAM42352.1 - 0.033 13.9 0.0 0.047 13.4 0.0 1.4 1 1 0 1 1 1 0 Prokaryotic E2 family B WD40 PF00400.32 CAM42353.1 - 1.8e-26 91.9 17.8 3.6e-06 27.6 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM42353.1 - 1.9e-20 73.0 2.4 1.5e-07 31.6 0.1 5.6 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CAM42353.1 - 5.8e-07 29.6 0.0 0.09 12.6 0.0 3.1 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CAM42353.1 - 0.00039 19.5 0.2 0.57 9.1 0.0 3.0 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 CAM42353.1 - 0.042 13.2 0.3 4.6 6.5 0.0 3.1 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.12 CAM42353.1 - 0.049 11.6 1.4 0.54 8.2 0.0 2.4 2 1 0 2 2 2 0 IKI3 family Pkinase PF00069.25 CAM42354.1 - 4.8e-46 157.3 0.0 7.9e-46 156.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM42354.1 - 5e-27 94.8 0.0 1.2e-26 93.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 CAM42354.1 - 5.2e-07 29.3 2.6 0.00013 21.7 0.0 3.3 3 0 0 3 3 3 1 Leucine rich repeat Kinase-like PF14531.6 CAM42354.1 - 3.7e-05 23.2 0.1 0.0027 17.1 0.0 2.3 2 0 0 2 2 2 1 Kinase-like LRR_4 PF12799.7 CAM42354.1 - 4e-05 23.9 0.8 0.6 10.6 0.0 3.7 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) zf-B_box PF00643.24 CAM42354.1 - 0.0014 18.7 23.6 0.0044 17.2 2.9 3.2 3 0 0 3 3 3 2 B-box zinc finger zf-UBR PF02207.20 CAM42354.1 - 0.013 15.6 1.4 0.013 15.6 1.4 3.2 3 0 0 3 3 2 0 Putative zinc finger in N-recognin (UBR box) APH PF01636.23 CAM42354.1 - 0.046 13.6 0.5 0.74 9.7 0.3 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family LRR_1 PF00560.33 CAM42354.1 - 0.074 13.6 0.1 34 5.5 0.0 3.5 2 0 0 2 2 2 0 Leucine Rich Repeat ZZ PF00569.17 CAM42354.1 - 0.12 12.2 23.1 0.45 10.4 7.1 2.7 2 0 0 2 2 2 0 Zinc finger, ZZ type zf-H2C2_5 PF13909.6 CAM42354.1 - 0.56 10.0 2.6 1.6 8.6 2.6 1.9 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-C3HC4_3 PF13920.6 CAM42354.1 - 2.9 7.8 16.1 1.6 8.6 3.8 2.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) C1_2 PF03107.16 CAM42354.1 - 5.3 7.4 34.1 0.13 12.6 12.1 3.0 3 0 0 3 3 3 0 C1 domain GCV_T PF01571.21 CAM42355.1 - 4.5e-08 32.8 0.0 6.7e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Propep_M14 PF02244.16 CAM42355.1 - 0.091 13.2 0.1 0.22 11.9 0.1 1.6 1 0 0 1 1 1 0 Carboxypeptidase activation peptide SET PF00856.28 CAM42356.1 - 4.7e-08 33.6 0.0 8.3e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 SET domain CGI-121 PF08617.10 CAM42357.2 - 0.00027 21.1 0.0 0.00051 20.2 0.0 1.6 1 1 0 1 1 1 1 Kinase binding protein CGI-121 Cyclin_C_2 PF16899.5 CAM42357.2 - 0.051 14.0 0.4 0.12 12.8 0.4 1.9 1 1 0 1 1 1 0 Cyclin C-terminal domain CGI-121 PF08617.10 CAM42358.1 - 0.00077 19.6 0.3 0.0015 18.7 0.3 1.7 1 1 0 1 1 1 1 Kinase binding protein CGI-121 Serendipity_A PF05482.12 CAM42358.1 - 0.17 10.5 0.1 0.26 9.9 0.1 1.2 1 0 0 1 1 1 0 Serendipity locus alpha protein (SRY-A) Cyclin_C_2 PF16899.5 CAM42358.1 - 0.2 12.0 2.9 0.12 12.7 0.4 2.2 2 1 0 2 2 2 0 Cyclin C-terminal domain Inhibitor_I42 PF09394.10 CAM42359.1 - 2.1e-17 63.3 0.2 2.5e-17 63.1 0.2 1.1 1 0 0 1 1 1 1 Chagasin family peptidase inhibitor I42 Big_3_3 PF13750.6 CAM42359.1 - 0.049 13.3 0.0 0.053 13.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) CzcE PF16986.5 CAM42359.1 - 0.12 12.7 0.1 0.3 11.4 0.0 1.6 2 0 0 2 2 2 0 Heavy-metal resistance protein CzcE AMP-binding PF00501.28 CAM42360.2 - 6e-14 51.5 5.6 0.00075 18.2 0.0 5.0 4 1 0 4 4 4 4 AMP-binding enzyme DUF620 PF04788.12 CAM42360.2 - 0.066 12.6 0.0 12 5.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF620) RRM_1 PF00076.22 CAM42361.1 - 1.9e-16 59.6 0.0 4.9e-16 58.3 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.13 CAM42361.1 - 0.0055 16.8 11.8 0.0058 16.7 11.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RRM_5 PF13893.6 CAM42361.1 - 0.049 13.2 0.1 0.46 10.1 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2076 PF09849.9 CAM42361.1 - 2.1 8.3 22.4 3 7.8 22.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Mannitol_dh_C PF08125.13 CAM42362.1 - 0.16 11.4 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Mannitol dehydrogenase C-terminal domain adh_short PF00106.25 CAM42363.1 - 6.4e-20 71.4 0.6 1.4e-19 70.3 0.6 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CAM42363.1 - 1.5e-11 44.3 0.5 5.2e-11 42.5 0.6 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CAM42363.1 - 3.8e-07 30.2 0.5 7.8e-07 29.2 0.5 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CAM42363.1 - 0.00051 19.6 0.5 0.0009 18.8 0.5 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 CAM42363.1 - 0.01 16.2 0.1 0.021 15.3 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.19 CAM42363.1 - 0.012 14.9 0.2 0.39 10.0 0.0 2.8 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 CAM42363.1 - 0.055 12.9 0.0 0.084 12.3 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase ApbA PF02558.16 CAM42363.1 - 0.056 13.1 0.7 0.092 12.4 0.1 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA LSDAT_euk PF18139.1 CAM42363.1 - 0.065 12.6 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 SLOG in TRPM ArsA_ATPase PF02374.15 CAM42363.1 - 0.096 11.8 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Anion-transporting ATPase DFP PF04127.15 CAM42363.1 - 0.17 11.7 1.5 2.4 7.9 0.6 2.5 2 1 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein ETF PF01012.21 CAM42363.1 - 0.35 10.7 3.0 0.14 12.0 0.4 1.6 2 0 0 2 2 2 0 Electron transfer flavoprotein domain adh_short PF00106.25 CAM42364.2 - 8.3e-22 77.6 0.0 3.1e-12 46.4 0.0 3.2 2 1 1 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 CAM42364.2 - 1.1e-10 41.5 0.0 2.8e-06 27.1 0.0 2.3 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CAM42364.2 - 3.7e-06 27.0 0.0 7.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CAM42364.2 - 0.00065 19.2 0.0 0.0017 17.9 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 CAM42364.2 - 0.067 13.6 0.0 0.2 12.1 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding WVELL PF14043.6 CAM42365.1 - 0.025 14.4 0.3 0.052 13.4 0.3 1.5 1 0 0 1 1 1 0 WVELL protein Abhydrolase_2 PF02230.16 CAM42366.1 - 6.7e-40 137.2 0.0 8.4e-40 136.9 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 CAM42366.1 - 0.00022 20.6 0.1 0.15 11.3 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CAM42366.1 - 0.00085 20.0 0.2 0.0012 19.5 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 CAM42366.1 - 0.034 13.8 0.0 0.077 12.6 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 CAM42366.1 - 0.035 13.7 0.6 6.1 6.4 0.0 2.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold Esterase PF00756.20 CAM42366.1 - 0.049 13.3 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Esterase_phd PF10503.9 CAM42366.1 - 0.099 12.1 0.7 0.24 10.8 0.5 1.6 1 1 1 2 2 2 0 Esterase PHB depolymerase SPRY PF00622.28 CAM42369.1 - 0.034 14.3 0.0 0.085 13.0 0.0 1.6 1 0 0 1 1 1 0 SPRY domain Cyclin PF08613.11 CAM42370.1 - 1.6e-16 61.1 0.0 3e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CAM42370.1 - 1.9e-07 30.9 0.2 3.6e-07 30.0 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CAM42371.2 - 1.7e-21 77.2 0.0 5.6e-21 75.6 0.0 1.8 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CAM42371.2 - 1.4e-07 31.3 0.1 2.3e-07 30.6 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain ICL PF00463.21 CAM42371.2 - 0.2 10.1 0.0 0.3 9.5 0.0 1.1 1 0 0 1 1 1 0 Isocitrate lyase family PFU PF09070.11 CAM42372.1 - 3.5e-25 88.4 0.3 5.8e-25 87.8 0.3 1.3 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 CAM42372.1 - 6.9e-24 83.7 23.5 8.4e-05 23.3 0.0 8.9 9 0 0 9 9 9 5 WD domain, G-beta repeat PUL PF08324.11 CAM42372.1 - 2.9e-07 30.0 1.9 5.3e-07 29.2 1.9 1.4 1 0 0 1 1 1 1 PUL domain AsnC_trans_reg PF01037.21 CAM42372.1 - 0.061 13.3 0.0 2.3 8.3 0.0 3.2 3 0 0 3 3 3 0 Lrp/AsnC ligand binding domain PPTA PF01239.22 CAM42373.1 - 0.0043 16.7 8.6 0.15 11.8 1.9 4.0 3 0 0 3 3 3 2 Protein prenyltransferase alpha subunit repeat Pam16 PF03656.13 CAM42374.2 - 0.11 12.5 0.5 0.21 11.6 0.4 1.7 1 1 0 1 1 1 0 Pam16 DUF4574 PF15141.6 CAM42375.2 - 0.0045 16.8 0.6 0.017 15.0 0.6 2.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex assembly factor 3 UPF0242 PF06785.11 CAM42375.2 - 0.14 12.3 16.6 0.76 9.9 2.9 2.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF3138 PF11336.8 CAM42375.2 - 3.9 6.0 10.9 5 5.6 2.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) ADIP PF11559.8 CAM42375.2 - 5.4 7.1 27.6 0.76 9.9 7.8 3.2 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 CAM42375.2 - 6.2 7.5 15.9 6.7 7.4 0.4 3.7 3 1 1 4 4 4 0 Initiation control protein YabA Ins134_P3_kin PF05770.11 CAM42376.1 - 5.6e-06 26.0 0.0 0.016 14.7 0.0 3.4 3 0 0 3 3 3 3 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain SLT_L PF14718.6 CAM42377.1 - 0.045 13.9 0.6 0.11 12.7 0.1 1.9 2 0 0 2 2 2 0 Soluble lytic murein transglycosylase L domain LIF_OSM PF01291.17 CAM42378.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 LIF / OSM family AMMECR1 PF01871.17 CAM42379.2 - 0.024 14.3 0.2 0.057 13.0 0.2 1.6 1 0 0 1 1 1 0 AMMECR1 Seryl_tRNA_N PF02403.22 CAM42379.2 - 4.2 7.6 22.2 2.3 8.5 8.9 3.5 2 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Golgin_A5 PF09787.9 CAM42379.2 - 4.3 6.7 44.2 0.26 10.7 26.1 2.3 2 0 0 2 2 2 0 Golgin subfamily A member 5 Fib_alpha PF08702.10 CAM42379.2 - 5.3 7.2 26.4 0.076 13.2 6.1 3.4 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family PD40 PF07676.12 CAM42380.1 - 0.041 13.8 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat DUF3287 PF11690.8 CAM42380.1 - 0.047 13.4 0.1 0.094 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) AKAP95 PF04988.12 CAM42380.1 - 0.2 11.9 0.4 0.36 11.1 0.4 1.3 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) STOP PF05217.12 CAM42381.1 - 2.2 8.6 14.1 1.8 9.0 11.4 2.4 2 1 0 2 2 2 0 STOP protein PCIF1_WW PF12237.8 CAM42383.1 - 7.6e-13 48.4 0.0 1.6e-12 47.4 0.0 1.6 1 1 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain PI3_PI4_kinase PF00454.27 CAM42384.1 - 3.1e-43 148.4 0.0 3.9e-28 98.9 0.0 2.3 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 CAM42384.1 - 3.7e-23 81.9 0.0 8.3e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 CAM42384.1 - 0.00067 19.6 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 CAM42384.1 - 0.021 14.2 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) TFCD_C PF12612.8 CAM42385.1 - 1.1e-30 106.9 0.1 4.5e-30 104.9 0.1 2.1 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.6 CAM42385.1 - 1.6e-10 41.2 11.3 0.0045 17.4 0.1 7.2 6 0 0 6 6 6 3 HEAT repeats Cnd1 PF12717.7 CAM42385.1 - 0.00011 22.3 0.5 1.3 9.1 0.0 4.9 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 CAM42385.1 - 0.075 12.2 0.1 8.6 5.5 0.0 3.1 4 0 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 CAM42385.1 - 0.49 10.8 0.0 0.49 10.8 0.0 11.6 13 1 1 14 14 14 0 HEAT repeat adh_short_C2 PF13561.6 CAM42386.1 - 1.4e-45 155.6 1.5 1.9e-45 155.2 1.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CAM42386.1 - 1.7e-44 151.6 2.3 2.2e-44 151.3 2.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CAM42386.1 - 1.2e-09 38.4 3.2 7.2e-09 35.8 3.2 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CAM42386.1 - 1.1e-06 28.2 0.8 6.6e-06 25.8 0.8 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CAM42386.1 - 0.00067 19.6 0.6 0.00085 19.3 0.6 1.3 1 0 0 1 1 1 1 NAD(P)H-binding AlaDh_PNT_C PF01262.21 CAM42386.1 - 0.0024 17.2 0.7 0.0043 16.4 0.7 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 CAM42386.1 - 0.0027 17.8 0.5 0.0055 16.8 0.2 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 CAM42386.1 - 0.0056 16.9 1.4 0.0089 16.3 1.1 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 CAM42386.1 - 0.0062 16.4 0.6 0.011 15.6 0.6 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 CAM42386.1 - 0.013 14.6 1.1 0.019 14.1 1.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DAO PF01266.24 CAM42386.1 - 0.016 14.8 0.1 0.021 14.5 0.1 1.3 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CAM42386.1 - 0.046 13.0 0.1 0.074 12.3 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 CAM42386.1 - 0.051 13.8 1.5 0.065 13.5 0.3 1.7 2 0 0 2 2 2 0 TrkA-N domain ApbA PF02558.16 CAM42386.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glyco_transf_9 PF01075.17 CAM42386.1 - 0.068 12.5 0.2 0.16 11.2 0.2 1.6 2 0 0 2 2 2 0 Glycosyltransferase family 9 (heptosyltransferase) NAD_binding_8 PF13450.6 CAM42386.1 - 0.083 13.1 0.1 0.2 11.9 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Glyco_transf_4 PF13439.6 CAM42386.1 - 0.091 12.8 0.0 2.2 8.2 0.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase Family 4 GDP_Man_Dehyd PF16363.5 CAM42386.1 - 0.093 12.1 0.0 0.33 10.3 0.0 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase ATPgrasp_N PF18130.1 CAM42386.1 - 0.097 13.2 0.0 0.21 12.2 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp N-terminal domain NAD_binding_7 PF13241.6 CAM42386.1 - 0.15 12.5 0.8 0.34 11.4 0.8 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding NmrA PF05368.13 CAM42386.1 - 0.21 11.1 2.0 0.23 11.0 0.9 1.5 2 0 0 2 2 2 0 NmrA-like family DFP PF04127.15 CAM42386.1 - 0.46 10.3 4.7 0.25 11.2 0.7 2.0 1 1 1 2 2 2 0 DNA / pantothenate metabolism flavoprotein BolA PF01722.18 CAM42387.1 - 1.1e-14 54.4 0.0 1.4e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein Ribosomal_L26 PF16906.5 CAM42388.1 - 1.8e-37 127.7 1.3 2.3e-37 127.3 1.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 CAM42388.1 - 4e-06 26.6 0.5 1e-05 25.3 0.5 1.8 1 1 0 1 1 1 1 KOW motif Transketolase_N PF00456.21 CAM42389.1 - 6.3e-139 462.6 0.1 9.1e-139 462.1 0.1 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 CAM42389.1 - 4.3e-45 153.6 0.0 8.2e-45 152.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CAM42389.1 - 1e-08 35.1 0.0 2.4e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 CAM42389.1 - 0.0001 21.6 0.0 0.00033 20.0 0.0 1.7 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 CAM42389.1 - 0.00012 21.9 0.3 0.00077 19.3 0.1 2.4 1 1 1 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Terpene_synth PF01397.21 CAM42389.1 - 0.0032 17.2 0.1 0.0078 15.9 0.0 1.6 2 0 0 2 2 2 1 Terpene synthase, N-terminal domain E1_dh PF00676.20 CAM42389.1 - 0.084 11.8 0.0 0.23 10.4 0.0 1.6 1 1 0 1 1 1 0 Dehydrogenase E1 component Ribosomal_S8e PF01201.22 CAM42391.1 - 9.2e-47 158.7 2.4 1.1e-46 158.4 2.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Kelch_3 PF13415.6 CAM42392.1 - 3.4e-39 132.4 6.4 2.3e-09 37.3 0.0 7.3 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_1 PF01344.25 CAM42392.1 - 1.5e-36 123.7 20.7 3.7e-08 32.8 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 CAM42392.1 - 6.3e-34 115.7 18.8 2e-06 27.7 0.1 6.9 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 CAM42392.1 - 2.3e-31 107.3 15.6 1.9e-07 30.9 0.5 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 CAM42392.1 - 1.7e-29 101.1 10.2 2.4e-07 30.8 0.0 6.5 5 1 1 6 6 6 5 Kelch motif Kelch_2 PF07646.15 CAM42392.1 - 1.2e-26 91.6 15.3 1.8e-06 27.7 0.4 6.5 6 1 0 6 6 6 6 Kelch motif HMG_CoA_synt_N PF01154.17 CAM42394.1 - 2.3e-11 43.9 0.1 4.2e-11 43.0 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 CAM42394.1 - 1.2e-06 28.4 0.1 9.2e-05 22.2 0.0 2.6 2 1 0 2 2 2 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal ACP_syn_III PF08545.10 CAM42394.1 - 0.026 14.4 0.8 0.05 13.5 0.2 1.8 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DsrH PF04077.12 CAM42395.1 - 0.12 12.6 0.2 1.5 9.0 0.0 2.4 2 0 0 2 2 2 0 DsrH like protein UQ_con PF00179.26 CAM42396.1 - 1.5e-44 151.1 0.2 1.6e-44 150.9 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 CAM42396.1 - 0.00087 19.1 0.3 0.0015 18.4 0.3 1.4 1 1 0 1 1 1 1 UEV domain RWD PF05773.22 CAM42396.1 - 0.0009 19.5 0.2 0.0012 19.1 0.2 1.4 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 CAM42396.1 - 0.0094 15.7 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UQ_con PF00179.26 CAM42397.1 - 6e-07 29.2 0.0 1.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CAM42397.1 - 0.1 12.9 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 RWD domain Nbs1_C PF08599.10 CAM42398.1 - 0.16 12.2 0.2 0.78 9.9 0.1 2.2 2 1 1 3 3 3 0 DNA damage repair protein Nbs1 GDPD PF03009.17 CAM42399.1 - 6.2e-21 75.3 0.0 8.3e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Utp8 PF10395.9 CAM42399.1 - 0.076 11.5 0.0 0.094 11.2 0.0 1.0 1 0 0 1 1 1 0 Utp8 family Vps54_N PF10475.9 CAM42400.1 - 2.3e-13 50.1 5.3 5.2e-13 48.9 5.3 1.7 1 1 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 CAM42400.1 - 3.4e-12 46.6 2.4 2.3e-11 43.9 0.2 2.8 3 0 0 3 3 3 1 Protein of unknown function C-terminus (DUF2451) Sec8_exocyst PF04048.14 CAM42400.1 - 0.00061 19.7 0.5 0.0014 18.5 0.5 1.5 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps51 PF08700.11 CAM42400.1 - 0.057 13.5 0.1 0.15 12.2 0.1 1.7 1 0 0 1 1 1 0 Vps51/Vps67 FlxA PF14282.6 CAM42401.1 - 0.0083 16.1 4.0 0.0083 16.1 4.0 14.4 6 4 11 18 18 17 2 FlxA-like protein DUF3800 PF12686.7 CAM42401.1 - 0.18 12.5 0.0 48 4.6 0.0 4.9 2 2 0 2 2 2 0 Protein of unknown function (DUF3800) NRN1 PF15056.6 CAM42401.1 - 1.2 9.3 19.3 0.41 10.8 0.4 5.8 5 0 0 5 5 5 0 Neuritin protein family DUF2140 PF09911.9 CAM42402.1 - 0.049 13.2 0.0 0.089 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) Wzz PF02706.15 CAM42402.1 - 0.1 12.9 1.0 0.23 11.8 0.5 1.8 2 0 0 2 2 2 0 Chain length determinant protein GGDEF_2 PF17853.1 CAM42402.1 - 0.11 12.8 1.3 0.29 11.4 0.2 2.2 2 1 0 2 2 2 0 GGDEF-like domain VirB8 PF04335.13 CAM42402.1 - 0.11 12.3 0.3 0.19 11.5 0.3 1.4 1 0 0 1 1 1 0 VirB8 protein PPR_3 PF13812.6 CAM42403.1 - 7.6e-13 48.3 0.0 1.6e-05 24.9 0.0 3.1 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 CAM42403.1 - 3.7e-06 27.0 0.0 0.0057 16.8 0.0 2.9 3 1 1 4 4 4 2 PPR repeat family PPR_long PF17177.4 CAM42403.1 - 4e-05 23.1 0.0 0.21 10.9 0.1 2.2 1 1 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 CAM42403.1 - 0.021 15.0 0.0 9 6.8 0.0 3.2 3 0 0 3 3 3 0 PPR repeat Ribosomal_L11_N PF03946.14 CAM42404.1 - 1e-16 60.5 0.5 1.8e-16 59.7 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CAM42404.1 - 1.7e-13 50.8 0.8 1.7e-13 50.8 0.8 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain DUF3792 PF12670.7 CAM42406.1 - 0.089 13.0 5.1 0.088 13.0 3.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3792) Cob_adeno_trans PF01923.18 CAM42407.1 - 3.5e-52 176.9 0.4 5.2e-52 176.3 0.4 1.3 1 0 0 1 1 1 1 Cobalamin adenosyltransferase DUF5522 PF17653.1 CAM42407.1 - 3.7e-20 71.6 2.6 3.7e-20 71.6 2.6 1.9 2 0 0 2 2 2 1 Family of unknown function (DUF5522) FA_desaturase PF00487.24 CAM42408.1 - 5.1e-18 65.8 20.5 5.1e-18 65.8 20.5 1.4 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 CAM42408.1 - 1.2e-08 35.0 0.1 1e-06 28.8 0.1 3.2 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DUF2269 PF10027.9 CAM42408.1 - 0.037 14.1 1.1 0.08 13.0 1.1 1.5 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) TssN PF17555.2 CAM42408.1 - 0.095 12.1 0.1 0.095 12.1 0.1 2.2 2 0 0 2 2 2 0 Type VI secretion system, TssN CAF1 PF04857.20 CAM42408.1 - 0.12 11.5 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease WD40 PF00400.32 CAM42409.1 - 2.2e-53 177.0 32.7 4.3e-08 33.7 0.1 8.9 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM42409.1 - 8.9e-20 70.8 6.1 0.003 17.8 0.0 6.4 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 CAM42409.1 - 1.8e-12 47.6 0.1 3e-12 46.9 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 CAM42409.1 - 2.1e-08 33.5 0.7 0.037 13.0 0.0 4.3 3 2 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CAM42409.1 - 9.8e-07 28.4 0.0 0.2 10.9 0.0 3.3 2 1 1 3 3 3 3 WD40-like domain eIF2A PF08662.11 CAM42409.1 - 1.3e-06 28.4 0.0 0.078 12.8 0.0 2.6 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 CAM42409.1 - 3.6e-05 23.6 1.9 8.4 6.5 0.0 4.9 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 CAM42409.1 - 0.0003 20.2 0.2 0.21 10.9 0.0 3.6 2 2 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal EBP PF05241.12 CAM42409.1 - 0.12 11.9 0.6 0.22 11.0 0.2 1.6 1 1 0 1 1 1 0 Emopamil binding protein DHHC PF01529.20 CAM42410.1 - 1.5e-13 51.1 10.9 1.5e-13 51.1 10.9 3.4 2 2 0 2 2 2 1 DHHC palmitoyltransferase zf-LITAF-like PF10601.9 CAM42410.1 - 0.038 14.2 0.4 0.038 14.2 0.4 3.2 3 2 1 4 4 4 0 LITAF-like zinc ribbon domain DUF35_N PF12172.8 CAM42410.1 - 0.11 12.4 3.8 0.25 11.3 0.9 2.5 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DEAD_2 PF06733.15 CAM42411.1 - 6.6e-40 136.6 0.0 7.1e-39 133.2 0.0 2.3 2 0 0 2 2 2 1 DEAD_2 Helicase_C_2 PF13307.6 CAM42411.1 - 6.8e-39 133.8 0.0 1.5e-38 132.7 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain HBB PF06777.11 CAM42411.1 - 4.1e-34 117.9 0.9 9.9e-29 100.4 0.3 2.6 2 0 0 2 2 2 2 Helical and beta-bridge domain DEAD PF00270.29 CAM42411.1 - 0.00012 21.9 0.3 0.01 15.6 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 CAM42411.1 - 0.00019 21.5 0.1 0.0027 17.7 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Glyco_transf_21 PF13506.6 CAM42411.1 - 0.002 17.6 0.4 0.1 12.0 0.0 3.2 3 0 0 3 3 3 1 Glycosyl transferase family 21 Flavi_DEAD PF07652.14 CAM42411.1 - 0.015 15.3 0.8 0.73 9.8 0.1 2.5 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_19 PF13245.6 CAM42411.1 - 0.034 14.5 0.1 0.12 12.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain CorC_HlyC PF03471.17 CAM42411.1 - 0.048 13.7 0.0 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 Transporter associated domain AAA_22 PF13401.6 CAM42411.1 - 0.061 13.6 0.9 0.55 10.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain SAPIS-gp6 PF16722.5 CAM42411.1 - 0.16 12.4 0.9 0.33 11.4 0.9 1.5 1 0 0 1 1 1 0 Pathogenicity island protein gp6 in Staphylococcus Cullin PF00888.22 CAM42412.1 - 3.7e-79 267.0 0.0 4.8e-79 266.6 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CAM42412.1 - 1.8e-22 79.2 0.6 5.5e-22 77.6 0.6 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain YojJ PF10372.9 CAM42413.1 - 0.11 12.6 1.0 6.2 7.0 0.1 3.0 2 1 1 3 3 3 0 Bacterial membrane-spanning protein N-terminus ABC_tran_CTD PF16326.5 CAM42413.1 - 0.15 12.3 0.1 13 6.1 0.0 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF682 PF05081.12 CAM42414.1 - 0.037 13.8 0.8 0.052 13.3 0.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF682) Baculo_PEP_C PF04513.12 CAM42414.1 - 0.26 11.3 3.3 0.25 11.4 0.3 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1319 PF07028.11 CAM42414.1 - 0.34 11.1 7.3 1.2 9.4 4.3 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1319) Enkurin PF13864.6 CAM42414.1 - 2.6 8.5 9.9 27 5.3 9.9 2.3 1 1 0 1 1 1 0 Calmodulin-binding ABC_tran_CTD PF16326.5 CAM42414.1 - 5.9 7.2 16.8 1.5 9.1 0.6 3.8 2 1 1 3 3 3 0 ABC transporter C-terminal domain DUF2076 PF09849.9 CAM42414.1 - 6.9 6.6 7.3 0.2 11.7 0.6 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Pkinase PF00069.25 CAM42415.1 - 1.3e-61 208.3 0.0 1.5e-61 208.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM42415.1 - 2.1e-40 138.7 0.0 2.7e-40 138.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 CAM42415.1 - 0.00019 21.1 0.1 0.035 13.7 0.0 2.2 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 CAM42415.1 - 0.00074 18.9 0.0 0.0018 17.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CAM42415.1 - 0.0033 16.3 0.0 0.0052 15.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RVT_1 PF00078.27 CAM42418.2 - 0.0027 17.3 0.0 0.0061 16.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A17 PF05380.13 CAM42418.2 - 0.0039 17.2 0.1 0.044 13.8 0.0 2.3 1 1 1 2 2 2 1 Pao retrotransposon peptidase RRM_1 PF00076.22 CAM42420.1 - 4.8e-32 109.6 1.0 1.1e-20 73.2 0.0 3.3 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CAM42420.1 - 0.00014 21.8 0.0 0.035 14.1 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 CAM42420.1 - 0.0014 18.9 0.6 2 8.6 0.0 3.2 2 2 1 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 CAM42420.1 - 0.0028 17.7 0.0 1.6 8.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 CAM42420.1 - 0.0091 15.6 0.0 0.043 13.4 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CAM42420.1 - 0.014 15.5 0.0 0.041 14.0 0.0 1.8 1 0 0 1 1 1 0 Limkain b1 RRM_occluded PF16842.5 CAM42420.1 - 0.14 12.0 0.0 0.46 10.4 0.0 1.8 2 0 0 2 2 2 0 Occluded RNA-recognition motif Meth_synt_2 PF01717.18 CAM42421.1 - 1.3e-153 511.0 0.0 1.9e-145 484.2 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 CAM42421.1 - 9e-120 399.9 0.0 2.7e-112 375.4 0.0 2.7 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain MIP PF00230.20 CAM42422.1 - 1.3e-51 175.5 10.5 1.6e-51 175.2 10.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein NiFe_hyd_3_EhaA PF17367.2 CAM42422.1 - 0.13 12.4 2.0 0.27 11.4 0.1 2.3 2 0 0 2 2 2 0 NiFe-hydrogenase-type-3 Eha complex subunit A RINGv PF12906.7 CAM42423.2 - 2.8e-11 43.3 5.6 2.8e-11 43.3 5.6 2.2 2 0 0 2 2 2 1 RING-variant domain MFS_2 PF13347.6 CAM42424.1 - 0.00025 19.8 13.9 0.00025 19.8 13.9 2.5 1 1 1 2 2 2 1 MFS/sugar transport protein BT1 PF03092.16 CAM42424.1 - 0.014 13.7 20.5 0.036 12.3 7.7 2.9 1 1 0 2 2 2 0 BT1 family DUF4534 PF15049.6 CAM42424.1 - 0.68 9.7 9.6 0.026 14.2 1.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4534) Pro_isomerase PF00160.21 CAM42425.1 - 4.4e-44 150.5 0.0 5.6e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ResIII PF04851.15 CAM42427.1 - 1.6e-16 60.8 0.0 4.2e-16 59.4 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CAM42427.1 - 3.2e-09 37.1 0.0 9.2e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T5orf172 PF10544.9 CAM42427.1 - 1e-08 35.7 0.0 2.3e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 T5orf172 domain DEAD PF00270.29 CAM42427.1 - 1.3e-07 31.5 0.0 2.2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase OrsD PF12013.8 CAM42427.1 - 0.073 13.5 0.5 0.26 11.7 0.5 2.0 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-CCCH_4 PF18044.1 CAM42428.1 - 0.00012 21.8 9.9 0.00068 19.4 4.8 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CAM42428.1 - 0.00035 20.5 1.0 0.00035 20.5 1.0 2.4 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 CAM42428.1 - 0.00037 20.3 10.7 0.0048 16.8 4.9 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 CAM42428.1 - 0.3 11.6 7.8 1.5 9.4 2.6 2.8 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 CAM42428.1 - 5 7.9 7.3 0.5 11.1 2.4 1.9 2 0 0 2 2 2 0 Torus domain zf-CCHH PF10283.9 CAM42428.1 - 10 6.2 9.4 7.9 6.6 0.1 3.1 3 0 0 3 3 3 0 PBZ domain Peptidase_C33 PF05412.12 CAM42429.1 - 0.17 11.9 0.0 0.81 9.7 0.0 2.1 2 0 0 2 2 2 0 Equine arterivirus Nsp2-type cysteine proteinase Peptidase_M22 PF00814.25 CAM42430.1 - 5.8e-84 282.0 0.0 6.9e-84 281.7 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family VCBS PF13517.6 CAM42431.1 - 1.7e-13 50.9 13.0 0.00073 20.1 5.0 6.6 5 1 2 7 7 7 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PQQ_2 PF13360.6 CAM42431.1 - 0.00027 20.6 0.1 0.53 9.8 0.0 2.6 1 1 0 2 2 2 2 PQQ-like domain FG-GAP PF01839.23 CAM42431.1 - 0.00075 19.6 21.9 0.59 10.3 3.5 5.8 5 0 0 5 5 5 4 FG-GAP repeat PQQ_3 PF13570.6 CAM42431.1 - 0.19 12.3 18.8 21 5.8 0.1 6.6 6 1 1 7 7 7 0 PQQ-like domain DUF2757 PF10955.8 CAM42433.1 - 0.031 14.5 0.9 0.15 12.3 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2757) Filament PF00038.21 CAM42433.1 - 0.37 10.3 70.1 0.12 11.9 30.6 3.8 1 1 2 3 3 3 0 Intermediate filament protein PMC2NT PF08066.12 CAM42433.1 - 0.76 10.5 8.7 0.21 12.3 0.3 4.3 4 1 1 5 5 5 0 PMC2NT (NUC016) domain YabA PF06156.13 CAM42433.1 - 2.8 8.6 0.0 2.8 8.6 0.0 7.2 2 1 3 5 5 5 0 Initiation control protein YabA DUF812 PF05667.11 CAM42433.1 - 10 4.9 60.1 17 4.1 31.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF812) UCH PF00443.29 CAM42434.1 - 3.3e-41 141.5 0.0 4.7e-41 141.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CAM42434.1 - 1.2e-10 41.5 0.1 2e-09 37.5 0.1 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 CAM42434.1 - 7.2e-09 35.3 0.0 3e-08 33.3 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin family Peptidase_C98 PF15499.6 CAM42434.1 - 0.0038 16.8 0.1 2.2 7.7 0.0 2.3 2 1 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase Ubiquitin_2 PF14560.6 CAM42434.1 - 0.027 14.9 0.0 0.068 13.6 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain Flagellar_rod PF05149.12 CAM42436.1 - 3.7e-104 348.2 29.2 3.7e-104 348.2 29.2 2.8 2 1 1 3 3 3 2 Paraflagellar rod protein Diphthamide_syn PF01866.17 CAM42437.1 - 5.7e-113 377.4 0.0 7.4e-113 377.0 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein BRCT PF00533.26 CAM42438.2 - 1.3e-09 38.2 0.0 0.15 12.4 0.0 4.8 5 0 0 5 5 5 3 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 CAM42438.2 - 1.8e-08 34.2 0.0 3.8e-07 29.9 0.0 2.7 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 CAM42438.2 - 5.8e-08 32.6 4.8 0.087 12.8 1.3 5.3 5 1 0 5 5 5 2 twin BRCT domain BRCT_2 PF16589.5 CAM42438.2 - 5.3e-06 26.7 0.0 0.57 10.6 0.0 4.0 4 0 0 4 4 4 2 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 CAM42438.2 - 0.0017 18.4 5.3 2.3 8.3 0.2 4.3 4 0 0 4 4 4 1 BRCA1 C Terminus (BRCT) domain Ins_P5_2-kin PF06090.12 CAM42438.2 - 0.14 11.5 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase Ribosomal_S8 PF00410.19 CAM42439.1 - 5.4e-21 74.9 0.0 6.8e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Folliculin PF11704.8 CAM42441.1 - 6.2e-08 32.7 1.4 9.7e-08 32.1 0.0 2.0 2 1 0 2 2 2 1 Vesicle coat protein involved in Golgi to plasma membrane transport Folliculin_C PF16692.5 CAM42441.1 - 1.3e-07 31.6 0.0 2.3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Folliculin C-terminal domain CENP-X PF09415.10 CAM42441.1 - 0.28 11.5 2.1 4.8 7.6 0.0 2.8 1 1 1 2 2 2 0 CENP-S associating Centromere protein X Herpes_capsid PF06112.11 CAM42441.1 - 3 7.9 7.1 5.8 7.0 7.1 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Bac_surface_Ag PF01103.23 CAM42442.1 - 2.2e-20 73.4 0.5 3e-20 73.0 0.5 1.2 1 0 0 1 1 1 1 Surface antigen Pyr_redox_2 PF07992.14 CAM42443.2 - 5e-46 157.3 0.1 7.9e-46 156.6 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CAM42443.2 - 1.6e-19 70.2 0.2 4.5e-19 68.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CAM42443.2 - 1.5e-18 67.1 2.0 3.2e-16 59.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CAM42443.2 - 7.5e-08 32.1 0.0 1.3e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 CAM42443.2 - 2.4e-06 26.9 2.3 0.014 14.5 0.1 3.4 4 0 0 4 4 4 2 Glucose inhibited division protein A HI0933_like PF03486.14 CAM42443.2 - 3.9e-06 25.8 1.5 0.00087 18.1 0.5 3.3 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.24 CAM42443.2 - 6.1e-06 26.0 6.5 0.0011 18.7 0.1 3.2 2 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CAM42443.2 - 7.7e-06 25.4 10.7 0.0038 16.5 0.7 3.9 4 1 1 5 5 5 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CAM42443.2 - 8.9e-06 25.2 0.1 0.021 14.1 0.0 3.2 3 0 0 3 3 3 2 FAD binding domain K_oxygenase PF13434.6 CAM42443.2 - 2.9e-05 23.4 0.0 7.7e-05 22.0 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 CAM42443.2 - 0.00046 19.5 0.2 0.041 13.1 0.0 2.4 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 CAM42443.2 - 0.00051 19.4 0.1 0.46 9.8 0.1 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 CAM42443.2 - 0.00065 18.9 0.7 0.00065 18.9 0.7 2.7 4 0 0 4 4 4 1 FAD binding domain ThiF PF00899.21 CAM42443.2 - 0.00084 18.8 0.0 0.0019 17.6 0.0 1.5 1 0 0 1 1 1 1 ThiF family NAD_binding_8 PF13450.6 CAM42443.2 - 0.0082 16.4 4.5 0.8 10.0 1.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 CAM42443.2 - 0.013 15.4 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 CAM42443.2 - 0.015 14.4 0.6 0.96 8.4 0.3 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 CAM42443.2 - 0.039 13.3 0.2 0.1 12.0 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1314 PF07013.11 CAM42443.2 - 0.12 12.2 0.0 0.34 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1314) XPG_N PF00752.17 CAM42444.1 - 0.031 14.7 0.1 0.12 12.8 0.0 2.0 2 0 0 2 2 2 0 XPG N-terminal domain Glyco_hydro_67C PF07477.12 CAM42444.1 - 0.048 13.2 1.7 0.068 12.7 0.5 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 67 C-terminus DUF1993 PF09351.10 CAM42444.1 - 0.26 11.4 8.4 0.25 11.5 4.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1993) BLOC1_2 PF10046.9 CAM42444.1 - 0.27 11.6 14.6 3.9 7.8 0.0 4.2 2 1 3 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.11 CAM42444.1 - 0.29 11.5 10.9 2.2 8.7 0.1 4.6 4 1 0 5 5 5 0 Flagella accessory protein C (FlaC) Filament PF00038.21 CAM42444.1 - 0.37 10.3 26.4 0.21 11.1 3.5 2.8 1 1 1 2 2 2 0 Intermediate filament protein Sugarporin_N PF11471.8 CAM42444.1 - 0.43 10.6 6.6 5.6 7.0 0.8 3.3 1 1 1 2 2 2 0 Maltoporin periplasmic N-terminal extension DOG1 PF14144.6 CAM42444.1 - 0.64 10.3 8.3 0.11 12.7 0.7 3.2 3 1 0 3 3 3 0 Seed dormancy control DUF1664 PF07889.12 CAM42444.1 - 0.69 10.0 18.6 0.63 10.1 6.4 3.6 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) Ribosomal_S30AE PF02482.19 CAM42444.1 - 0.86 10.4 6.4 12 6.8 0.6 3.7 2 2 1 3 3 3 0 Sigma 54 modulation protein / S30EA ribosomal protein Cnn_1N PF07989.11 CAM42444.1 - 0.88 9.8 21.4 0.18 12.0 1.0 4.5 2 2 1 3 3 3 0 Centrosomin N-terminal motif 1 DUF2730 PF10805.8 CAM42444.1 - 1.9 8.6 10.9 4.7 7.4 0.7 3.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Snapin_Pallidin PF14712.6 CAM42444.1 - 2.3 8.7 28.5 1.1 9.8 1.4 4.7 2 2 2 4 4 4 0 Snapin/Pallidin NPV_P10 PF05531.12 CAM42444.1 - 2.3 8.7 17.5 16 6.1 0.0 4.7 3 1 2 5 5 5 0 Nucleopolyhedrovirus P10 protein TolA_bind_tri PF16331.5 CAM42444.1 - 2.7 8.1 38.0 2 8.6 4.2 5.2 2 1 3 5 5 5 0 TolA binding protein trimerisation DIT1_PvcA PF05141.12 CAM42444.1 - 4.5 6.6 12.9 7.2 6.0 5.4 2.3 1 1 0 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein Cep57_CLD PF14073.6 CAM42444.1 - 5.1 7.1 31.2 0.21 11.6 21.1 2.2 1 1 0 2 2 2 0 Centrosome localisation domain of Cep57 FapA PF03961.13 CAM42444.1 - 5.4 5.5 14.2 3.9 6.0 1.3 2.2 1 1 1 2 2 2 0 Flagellar Assembly Protein A PIH1_CS PF18201.1 CAM42445.1 - 2.3e-08 34.3 0.0 3.8e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 PIH1 CS-like domain RNA_pol_Rpb2_6 PF00562.28 CAM42447.1 - 1.7e-120 402.7 0.0 2.2e-120 402.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CAM42447.1 - 7.6e-42 143.1 0.0 1.1e-41 142.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 CAM42447.1 - 1.5e-31 108.6 0.0 6.5e-31 106.6 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 CAM42447.1 - 9e-24 84.2 0.0 1.6e-23 83.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 CAM42447.1 - 8.7e-23 80.4 1.9 1.8e-22 79.4 1.9 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 CAM42447.1 - 7.3e-21 74.1 2.5 7.4e-21 74.1 0.1 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 CAM42447.1 - 4.2e-09 36.8 0.6 1.1e-08 35.5 0.6 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 C1_1 PF00130.22 CAM42447.1 - 0.14 12.1 1.8 0.31 10.9 1.8 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) OrfB_Zn_ribbon PF07282.11 CAM42447.1 - 0.32 11.0 3.1 0.32 11.0 1.2 1.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Myb_DNA-binding PF00249.31 CAM42449.1 - 0.054 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Methyltr_RsmB-F PF01189.17 CAM42450.1 - 1e-67 227.7 0.0 2e-67 226.8 0.0 1.5 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 CAM42450.1 - 5.6e-08 33.2 0.0 2.9e-07 30.9 0.0 2.3 3 0 0 3 3 3 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 CAM42450.1 - 0.0011 19.1 0.0 0.0033 17.5 0.0 1.7 1 1 0 2 2 2 1 FtsJ-like methyltransferase PCMT PF01135.19 CAM42450.1 - 0.038 13.7 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Kinesin_assoc PF16183.5 CAM42450.1 - 0.095 12.8 1.1 0.29 11.3 1.1 1.8 1 0 0 1 1 1 0 Kinesin-associated Lin-8 PF03353.15 CAM42450.1 - 0.98 8.9 8.5 1.9 8.0 7.5 1.9 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist WD40 PF00400.32 CAM42451.2 - 1.1e-11 45.1 10.0 0.052 14.4 0.0 7.3 7 0 0 7 7 7 2 WD domain, G-beta repeat NLE PF08154.12 CAM42451.2 - 2.5e-10 40.7 0.1 4.5e-10 39.9 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain ANAPC4_WD40 PF12894.7 CAM42451.2 - 0.00043 20.5 0.2 2 8.8 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 CAM42451.2 - 0.11 11.7 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller CLP1_P PF16575.5 CAM42452.1 - 2.8e-10 40.3 0.0 1.1e-09 38.4 0.0 1.9 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 CAM42452.1 - 5.8e-09 36.1 0.0 1.1e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 CAM42452.1 - 0.00033 21.0 0.0 0.0007 20.0 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 DUF4746 PF15928.5 CAM42453.1 - 0.0022 17.5 11.6 0.0032 17.0 11.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4746) TFIIF_alpha PF05793.12 CAM42453.1 - 0.0029 16.3 14.2 0.0032 16.1 14.2 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 CAM42453.1 - 0.0055 15.0 18.7 0.0062 14.8 18.7 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 CAM42453.1 - 0.0069 15.9 17.6 0.0079 15.7 17.6 1.2 1 0 0 1 1 1 1 SDA1 SpoIIIAH PF12685.7 CAM42453.1 - 0.016 15.1 6.1 0.02 14.8 6.1 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Tim54 PF11711.8 CAM42453.1 - 0.023 13.5 2.6 0.027 13.2 2.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NOA36 PF06524.12 CAM42453.1 - 0.2 10.9 28.2 0.26 10.6 28.2 1.1 1 0 0 1 1 1 0 NOA36 protein DUF4604 PF15377.6 CAM42453.1 - 0.25 11.8 15.6 0.47 10.9 15.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Spore_coat_CotO PF14153.6 CAM42453.1 - 0.31 11.0 9.8 0.39 10.6 9.8 1.2 1 0 0 1 1 1 0 Spore coat protein CotO CDC45 PF02724.14 CAM42453.1 - 0.39 9.0 12.7 0.46 8.7 12.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.22 CAM42453.1 - 0.54 9.4 2.6 0.53 9.4 2.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 CAM42453.1 - 0.56 8.9 5.2 0.65 8.7 5.2 1.1 1 0 0 1 1 1 0 Presenilin RRN3 PF05327.11 CAM42453.1 - 2 6.9 12.9 2.4 6.6 12.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Afi1 PF07792.12 CAM42453.1 - 3.7 8.0 12.3 6.9 7.2 12.3 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Hid1 PF12722.7 CAM42453.1 - 3.7 5.5 4.0 3.9 5.5 4.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Cwf_Cwc_15 PF04889.12 CAM42453.1 - 4.1 7.0 28.3 6.2 6.5 28.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF913 PF06025.12 CAM42453.1 - 5 6.0 7.4 7.5 5.4 7.4 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TPR_MLP1_2 PF07926.12 CAM42454.1 - 0.01 15.9 6.6 0.01 15.9 6.6 10.3 1 1 9 11 11 11 2 TPR/MLP1/MLP2-like protein PilM PF07419.12 CAM42454.1 - 0.017 15.3 0.2 4.7 7.4 0.0 2.7 2 0 0 2 2 2 0 PilM DUF2935 PF11155.8 CAM42454.1 - 0.22 11.8 0.0 0.22 11.8 0.0 6.9 3 3 0 3 3 3 0 Domain of unknown function (DUF2935) Sh_2 PF17512.2 CAM42454.1 - 8.1 6.2 6.5 8.8 6.1 1.8 2.8 1 1 1 2 2 2 0 Metapneumovirus Small hydrophobic protein Cupin_4 PF08007.12 CAM42455.2 - 1.5e-41 142.9 0.2 3.7e-41 141.6 0.2 1.6 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 CAM42455.2 - 5.8e-07 29.5 0.0 1.2e-05 25.2 0.0 2.5 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 CAM42455.2 - 0.03 14.0 0.0 0.083 12.6 0.0 1.7 1 0 0 1 1 1 0 Cupin domain JmjC PF02373.22 CAM42455.2 - 0.064 13.7 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 JmjC domain, hydroxylase Helicase_C PF00271.31 CAM42456.1 - 2.1e-10 40.9 0.0 5.4e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CAM42456.1 - 2.4e-06 27.4 0.0 6.3e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4548 PF15081.6 CAM42458.2 - 0.14 12.0 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4548) COPIIcoated_ERV PF07970.12 CAM42459.1 - 8.8e-18 65.0 0.0 1.5e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CAM42459.1 - 1.6e-08 34.8 0.0 2.8e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Kinesin PF00225.23 CAM42460.1 - 3.9e-88 295.6 0.0 5.7e-88 295.0 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CAM42460.1 - 9.5e-17 61.3 0.0 1.6e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding DUF3972 PF13118.6 CAM42460.1 - 0.15 12.5 0.1 0.39 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) TMF_DNA_bd PF12329.8 CAM42460.1 - 5.8 7.0 6.0 0.75 9.8 0.1 2.5 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding CRAL_TRIO PF00650.20 CAM42461.2 - 1.7e-11 44.1 0.0 3e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO PF00650.20 CAM42462.1 - 3.2e-13 49.7 0.0 5.3e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain Aa_trans PF01490.18 CAM42463.1 - 3.6e-42 144.5 34.6 4.4e-42 144.2 34.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CAM42463.1 - 1e-09 37.9 20.5 2.6e-09 36.6 20.5 1.6 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family AA_permease_2 PF13520.6 CAM42463.1 - 3.4e-08 32.8 24.8 3.4e-08 32.8 24.8 2.0 2 0 0 2 2 2 1 Amino acid permease VIT1 PF01988.19 CAM42463.1 - 0.0068 16.3 0.0 0.0068 16.3 0.0 3.2 3 0 0 3 3 3 1 VIT family Aa_trans PF01490.18 CAM42464.1 - 8.8e-51 172.9 32.8 1.1e-50 172.5 32.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Holin_SPP1 PF04688.13 CAM42464.1 - 1.1 9.5 0.0 1.1 9.5 0.0 2.8 3 0 0 3 3 3 0 SPP1 phage holin DUF5075 PF16825.5 CAM42465.1 - 3.6e-06 26.8 3.4 1.1e-05 25.2 3.4 1.9 1 1 0 1 1 1 1 IGP family C-type lectin domain TMEM154 PF15102.6 CAM42465.1 - 0.00076 19.4 4.0 0.002 18.1 4.0 1.6 1 0 0 1 1 1 1 TMEM154 protein family DUF4366 PF14283.6 CAM42465.1 - 0.0035 17.4 0.4 0.0065 16.5 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Dicty_REP PF05086.12 CAM42465.1 - 0.12 10.3 2.9 0.14 10.1 2.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Hum_adeno_E3A PF05393.11 CAM42465.1 - 0.48 10.4 6.7 2 8.4 0.2 2.6 2 1 0 2 2 2 0 Human adenovirus early E3A glycoprotein DUF5305 PF17231.2 CAM42465.1 - 0.77 9.1 6.4 1.4 8.3 6.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Aa_trans PF01490.18 CAM42466.1 - 2.5e-51 174.7 28.8 2.9e-51 174.5 28.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CAM42466.1 - 9.6e-08 31.5 10.9 9.6e-08 31.5 10.9 2.2 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Aa_trans PF01490.18 CAM42467.1 - 4.8e-48 163.9 33.4 5.7e-48 163.6 33.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CAM42467.1 - 1.9e-06 27.2 19.5 1.9e-06 27.2 19.5 2.2 1 1 1 2 2 2 1 Tryptophan/tyrosine permease family DUF2208 PF09973.9 CAM42467.1 - 1.4 8.5 5.8 5.1 6.6 0.1 2.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) CRAL_TRIO PF00650.20 CAM42468.2 - 6.3e-13 48.8 0.0 1.2e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain DUF2189 PF09955.9 CAM42469.2 - 0.029 14.6 0.1 0.069 13.4 0.1 1.7 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2189) Kinase-PPPase PF03618.14 CAM42469.2 - 0.23 11.2 1.5 0.37 10.5 0.6 1.8 2 0 0 2 2 2 0 Kinase/pyrophosphorylase GTSE1_N PF15259.6 CAM42469.2 - 0.53 10.5 1.9 0.74 10.0 0.9 1.7 2 0 0 2 2 2 0 G-2 and S-phase expressed 1 Peptidase_C2 PF00648.21 CAM42471.2 - 1.2e-46 159.1 0.0 1.7e-46 158.6 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 CAM42471.2 - 1.5e-25 89.6 0.0 2.5e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.21 CAM42472.1 - 4.8e-30 104.6 0.0 8e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 CAM42472.1 - 5.4e-13 49.2 0.0 1.3e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) RRM_1 PF00076.22 CAM42473.1 - 8.4e-11 41.5 0.0 1.4e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CAM42473.1 - 0.00083 19.2 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 CAM42473.1 - 0.0016 18.5 0.0 0.0031 17.5 0.0 1.6 1 1 0 1 1 1 1 RNA binding motif DUF2169 PF09937.9 CAM42473.1 - 0.041 13.3 0.0 5.8 6.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2169) GST_C_5 PF16865.5 CAM42475.1 - 1.7e-86 285.9 1.1 1.9e-46 157.1 0.1 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CAM42475.1 - 6.1e-30 103.4 0.1 1.9e-13 50.6 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CAM42475.1 - 9.7e-27 93.1 0.3 4.2e-13 49.4 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CAM42475.1 - 1.6e-19 70.0 0.1 4.4e-09 36.6 0.0 2.7 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CAM42475.1 - 1.3e-14 54.0 1.6 1.1e-06 28.5 0.1 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 CAM42475.1 - 1.9e-11 44.0 0.4 2.8e-08 33.9 0.2 2.5 2 0 0 2 2 2 2 Glutaredoxin GST_C_3 PF14497.6 CAM42475.1 - 5.9e-06 26.4 0.0 0.0027 17.9 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CAM42475.1 - 9.8e-05 22.5 0.2 0.04 14.1 0.0 2.7 2 1 0 2 2 2 2 Glutathione S-transferase, C-terminal domain A_deamin PF02137.18 CAM42476.2 - 9e-22 77.9 0.1 1.4e-21 77.4 0.1 1.3 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Galactosyl_T PF01762.21 CAM42477.1 - 0.062 13.1 0.2 0.32 10.8 0.0 2.1 3 0 0 3 3 3 0 Galactosyltransferase DUF1935 PF09149.10 CAM42478.1 - 4.3e-18 65.6 0.0 7.5e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.21 CAM42478.1 - 1.9e-16 60.0 0.0 2.9e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease HCR PF07111.12 CAM42478.1 - 0.013 13.6 0.4 0.019 13.1 0.4 1.1 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) Peptidase_C2 PF00648.21 CAM42479.1 - 1.1e-36 126.4 0.0 1.8e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 CAM42479.1 - 7.1e-21 74.5 0.1 1.3e-20 73.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.21 CAM42480.2 - 5.2e-48 163.6 0.3 7.8e-48 163.0 0.3 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Peptidase_C2 PF00648.21 CAM42482.2 - 1.4e-66 224.5 0.1 1.8e-66 224.2 0.1 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 CAM42482.2 - 1.9e-17 63.5 0.2 4.5e-17 62.3 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) AAA_16 PF13191.6 CAM42483.1 - 0.0043 17.4 0.0 0.01 16.2 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 CAM42483.1 - 0.066 13.2 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sulfotransfer_4 PF17784.1 CAM42484.2 - 2.2e-40 138.8 0.0 5.5e-40 137.5 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase domain cNMP_binding PF00027.29 CAM42485.2 - 2.1e-22 79.0 0.6 8.1e-07 29.0 0.0 5.8 4 2 1 5 5 5 4 Cyclic nucleotide-binding domain DnaJ PF00226.31 CAM42487.1 - 8e-21 73.9 0.2 1.5e-20 73.0 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ-X PF14308.6 CAM42487.1 - 0.00042 19.8 0.5 0.00074 19.0 0.5 1.3 1 0 0 1 1 1 1 X-domain of DnaJ-containing TRM13 PF05206.14 CAM42488.1 - 1.9e-37 129.2 0.0 6e-25 88.3 0.0 3.1 1 1 1 2 2 2 2 Methyltransferase TRM13 zf-U11-48K PF05253.12 CAM42488.1 - 1.5e-10 40.7 1.6 4.3e-10 39.3 1.6 1.9 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger zf-TRM13_CCCH PF11722.8 CAM42488.1 - 7.7e-08 32.0 10.1 7.7e-08 32.0 10.1 2.2 2 0 0 2 2 2 1 CCCH zinc finger in TRM13 protein Methyltransf_32 PF13679.6 CAM42488.1 - 2.6 8.0 5.5 26 4.8 5.5 2.3 1 1 0 1 1 1 0 Methyltransferase domain ABC_membrane_2 PF06472.15 CAM42490.2 - 4.5e-69 232.8 4.6 6.7e-69 232.3 4.6 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 CAM42490.2 - 4.2e-16 59.7 0.0 7.8e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CAM42490.2 - 0.043 13.6 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CAM42490.2 - 0.25 11.8 0.1 0.41 11.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain Apt1 PF10351.9 CAM42491.2 - 0.0074 15.2 1.6 0.018 13.9 1.6 1.6 1 0 0 1 1 1 1 Golgi-body localisation protein domain Atg14 PF10186.9 CAM42491.2 - 0.04 13.0 15.9 0.11 11.5 1.1 3.6 3 1 0 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 MPS2 PF17060.5 CAM42491.2 - 0.28 10.4 11.1 0.25 10.5 2.4 2.2 2 0 0 2 2 2 0 Monopolar spindle protein 2 DUF501 PF04417.12 CAM42491.2 - 2 8.2 10.0 0.55 10.0 2.2 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF501) BBP1_C PF15272.6 CAM42491.2 - 2.1 8.1 6.2 0.36 10.6 1.2 2.2 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal FAM76 PF16046.5 CAM42491.2 - 6.4 6.0 15.6 6.5 6.0 1.1 3.2 3 0 0 3 3 3 0 FAM76 protein V-SNARE PF05008.15 CAM42491.2 - 6.5 7.2 9.7 20 5.7 1.3 3.1 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus GHMP_kinases_C PF08544.13 CAM42492.1 - 3.3e-16 59.4 0.5 6.7e-16 58.4 0.5 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 CAM42492.1 - 4.7e-12 46.0 0.5 1.2e-11 44.7 0.5 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain Scaffolding_pro PF11418.8 CAM42492.1 - 0.064 13.8 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Phi29 scaffolding protein Aa_trans PF01490.18 CAM42493.1 - 1.9e-46 158.6 40.7 2.4e-46 158.3 40.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CAM42493.1 - 4.5e-10 39.1 18.5 4.5e-10 39.1 18.5 2.1 1 1 0 2 2 2 1 Tryptophan/tyrosine permease family Aa_trans PF01490.18 CAM42494.1 - 4.6e-45 154.1 36.0 5.4e-45 153.8 36.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 CAM42494.1 - 3.4e-05 22.9 16.5 3.4e-05 22.9 16.5 3.0 1 1 2 3 3 3 2 Amino acid permease Trp_Tyr_perm PF03222.13 CAM42494.1 - 8.5e-05 21.8 15.2 8.5e-05 21.8 15.2 2.5 2 2 0 2 2 2 1 Tryptophan/tyrosine permease family Cytochrom_B_C PF00032.17 CAM42494.1 - 2.7 8.3 7.7 0.19 12.0 0.4 2.9 3 0 0 3 3 3 0 Cytochrome b(C-terminal)/b6/petD Aa_trans PF01490.18 CAM42495.1 - 2.3e-44 151.8 33.9 2.9e-44 151.4 33.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein FA_hydroxylase PF04116.13 CAM42496.1 - 2.8e-15 56.8 12.9 2.8e-15 56.8 12.9 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Ribosomal_L7Ae PF01248.26 CAM42498.1 - 8.1e-05 22.3 0.1 0.00023 20.8 0.1 1.8 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Antimicrobial19 PF08225.11 CAM42498.1 - 0.03 13.9 0.1 0.069 12.8 0.1 1.5 1 0 0 1 1 1 0 Pseudin antimicrobial peptide CK2S PF15011.6 CAM42498.1 - 0.055 13.4 0.6 0.23 11.3 0.7 2.0 2 0 0 2 2 2 0 Casein Kinase 2 substrate XTBD PF11952.8 CAM42500.1 - 0.048 13.4 0.0 0.2 11.5 0.0 2.1 1 0 0 1 1 1 0 XRN-Two Binding Domain, XTBD Cas6 PF09559.10 CAM42501.1 - 0.056 13.4 0.9 4.7 7.1 0.3 2.9 2 1 0 2 2 2 0 Cas6 Crispr C2 PF00168.30 CAM42505.1 - 1.1e-22 80.3 0.0 1.6e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 C2 domain CCDC53 PF10152.9 CAM42505.1 - 0.025 15.0 0.3 0.04 14.3 0.3 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex CEP76-C2 PF15627.6 CAM42505.1 - 0.028 14.0 0.0 0.045 13.3 0.0 1.3 1 1 0 1 1 1 0 CEP76 C2 domain DOCK-C2 PF14429.6 CAM42505.1 - 0.051 13.4 0.0 0.091 12.6 0.0 1.4 1 0 0 1 1 1 0 C2 domain in Dock180 and Zizimin proteins Peptidase_M41 PF01434.18 CAM42507.1 - 3.3e-44 151.0 0.0 8.1e-44 149.8 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CAM42507.1 - 1.3e-33 116.2 0.0 3e-33 115.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAM42507.1 - 7.4e-11 41.7 0.0 1.7e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 CAM42507.1 - 0.0025 17.9 0.0 0.006 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CAM42507.1 - 0.0028 17.7 0.7 0.064 13.3 0.7 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CAM42507.1 - 0.0037 17.5 0.5 0.74 10.1 0.1 2.7 1 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CAM42507.1 - 0.02 15.4 0.1 0.062 13.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CAM42507.1 - 0.021 15.2 2.3 0.039 14.4 0.1 2.5 2 1 1 3 3 3 0 AAA ATPase domain RuvB_N PF05496.12 CAM42507.1 - 0.042 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 CAM42507.1 - 0.055 13.2 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 CAM42507.1 - 0.1 12.8 0.0 0.31 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CAM42507.1 - 0.14 11.6 0.3 0.28 10.5 0.3 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Nodulin-like PF06813.13 CAM42509.1 - 4.2e-05 23.2 8.5 5.8e-05 22.7 8.5 1.2 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.16 CAM42511.1 - 1.5e-08 33.9 51.5 2.6e-08 33.2 24.8 3.8 2 2 1 3 3 3 2 Major Facilitator Superfamily Nodulin-like PF06813.13 CAM42511.1 - 0.0083 15.6 18.5 0.16 11.4 18.5 2.3 1 1 0 1 1 1 1 Nodulin-like DUF5516 PF17637.2 CAM42511.1 - 0.24 11.2 0.1 0.24 11.2 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5516) CesT PF05932.13 CAM42513.1 - 1.7e-15 57.2 1.3 1e-14 54.7 0.2 2.2 2 0 0 2 2 2 1 Tir chaperone protein (CesT) family DivIC PF04977.15 CAM42513.1 - 0.0037 17.0 0.8 0.0074 16.0 0.8 1.4 1 0 0 1 1 1 1 Septum formation initiator MYO10_CC PF16735.5 CAM42513.1 - 0.04 14.0 0.4 0.1 12.7 0.4 1.7 1 0 0 1 1 1 0 Unconventional myosin-X coiled coil domain DUF4407 PF14362.6 CAM42513.1 - 0.062 12.6 1.7 0.085 12.2 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ubiquitin PF00240.23 CAM42513.1 - 0.1 12.4 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin family ALIX_LYPXL_bnd PF13949.6 CAM42513.1 - 0.12 11.7 2.7 0.16 11.3 2.7 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV DUF1192 PF06698.11 CAM42513.1 - 0.22 11.6 2.5 30 4.8 2.8 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) DUF726 PF05277.12 CAM42514.1 - 0.16 10.8 0.4 0.27 10.1 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF726) PTA_PTB PF01515.19 CAM42515.2 - 0.018 14.3 0.2 0.052 12.9 0.0 1.6 1 1 0 1 1 1 0 Phosphate acetyl/butaryl transferase PGBA_C PF15437.6 CAM42515.2 - 0.022 15.1 3.4 0.052 13.9 3.4 1.6 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal BORCS7 PF16088.5 CAM42515.2 - 0.28 11.5 3.9 14 6.0 0.0 2.9 2 1 0 2 2 2 0 BLOC-1-related complex sub-unit 7 MscS_porin PF12795.7 CAM42515.2 - 5.1 6.6 13.3 3.5 7.1 0.4 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain C2 PF00168.30 CAM42516.1 - 4.9e-20 71.7 0.3 8.8e-20 70.9 0.2 1.4 2 0 0 2 2 2 1 C2 domain DOCK-C2 PF14429.6 CAM42516.1 - 0.02 14.7 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 C2 domain in Dock180 and Zizimin proteins C2 PF00168.30 CAM42517.1 - 1.2e-20 73.7 0.1 1.6e-20 73.3 0.1 1.2 1 0 0 1 1 1 1 C2 domain Ras PF00071.22 CAM42522.1 - 2.9e-23 82.3 0.3 5.6e-19 68.3 0.0 2.5 2 1 0 2 2 2 2 Ras family Roc PF08477.13 CAM42522.1 - 9.9e-16 58.0 0.1 2.5e-09 37.4 0.0 2.4 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAM42522.1 - 4.4e-08 32.8 0.0 3.4e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CAM42522.1 - 8e-08 32.0 0.4 1.4e-07 31.3 0.4 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CAM42522.1 - 5.6e-06 25.9 0.1 1.3e-05 24.7 0.1 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CAM42522.1 - 8.3e-05 22.7 0.1 0.0011 19.0 0.1 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase DLIC PF05783.11 CAM42522.1 - 0.39 9.5 2.0 4.4 6.0 0.1 2.7 2 1 1 3 3 3 0 Dynein light intermediate chain (DLIC) Dynamin_N PF00350.23 CAM42522.1 - 1.4 9.0 4.0 1.7 8.7 0.7 2.4 3 0 0 3 3 3 0 Dynamin family Aa_trans PF01490.18 CAM42523.2 - 1.8e-49 168.6 39.3 2.2e-49 168.3 39.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CAM42523.2 - 2.3e-07 30.2 34.6 1.1e-06 28.0 34.6 1.8 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family AA_permease_2 PF13520.6 CAM42523.2 - 3.7e-05 22.7 26.8 3.7e-05 22.7 26.8 2.1 2 0 0 2 2 2 1 Amino acid permease KIAA1430 PF13879.6 CAM42524.2 - 8.9e-18 64.9 0.3 1.4e-17 64.3 0.3 1.3 1 0 0 1 1 1 1 KIAA1430 homologue HCMV_UL139 PF12507.8 CAM42524.2 - 0.034 14.5 0.2 0.034 14.5 0.2 1.6 2 0 0 2 2 2 0 Human Cytomegalovirus UL139 protein Bax1-I PF01027.20 CAM42525.1 - 0.0088 15.9 0.6 0.0097 15.8 0.6 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2427 PF10348.9 CAM42525.1 - 0.019 14.7 0.6 0.025 14.4 0.5 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF2427) WCOR413 PF05562.11 CAM42525.1 - 0.023 14.6 0.1 0.039 13.9 0.0 1.4 1 1 0 1 1 1 0 Cold acclimation protein WCOR413 LapA_dom PF06305.11 CAM42525.1 - 0.52 10.2 3.8 0.94 9.3 3.8 1.6 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain PepSY_TM_like_2 PF16357.5 CAM42525.1 - 2 8.4 4.0 2.4 8.1 4.0 1.1 1 0 0 1 1 1 0 Putative PepSY_TM-like PP2C PF00481.21 CAM42528.2 - 3.4e-33 115.4 0.0 1e-28 100.7 0.1 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C zf-UBP_var PF17807.1 CAM42528.2 - 0.27 11.0 2.3 0.61 9.9 2.3 1.5 1 0 0 1 1 1 0 Variant UBP zinc finger zf-UBP PF02148.19 CAM42528.2 - 0.27 11.6 10.2 0.58 10.5 10.2 1.5 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein SfLAP PF11139.8 CAM42532.1 - 0.0076 15.7 1.4 0.011 15.2 1.4 1.2 1 0 0 1 1 1 1 Sap, sulfolipid-1-addressing protein Cytochrome_B PF00033.19 CAM42532.1 - 0.023 14.5 0.1 0.035 13.9 0.1 1.2 1 0 0 1 1 1 0 Cytochrome b/b6/petB Bax1-I PF01027.20 CAM42532.1 - 0.069 13.0 1.4 0.095 12.5 1.4 1.3 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF3397 PF11877.8 CAM42532.1 - 0.11 12.7 1.6 0.19 12.0 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3397) DUF2427 PF10348.9 CAM42532.1 - 0.18 11.6 3.0 0.14 12.0 1.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) CysA_C_terminal PF17850.1 CAM42534.2 - 0.15 12.6 0.7 0.3 11.7 0.7 1.6 1 1 0 1 1 1 0 CysA C-terminal regulatory domain HTH_1 PF00126.27 CAM42538.2 - 0.077 13.0 0.0 0.32 11.0 0.0 2.1 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family SH3BGR PF04908.15 CAM42540.1 - 0.18 12.0 1.3 18 5.6 0.1 2.6 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein DUF4217 PF13959.6 CAM42541.1 - 3.9e-05 23.8 0.0 9.5e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) RRM_1 PF00076.22 CAM42543.1 - 0.00011 21.9 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YhfH PF14149.6 CAM42543.1 - 0.011 15.7 1.4 0.25 11.3 0.1 2.5 2 0 0 2 2 2 0 YhfH-like protein SET PF00856.28 CAM42546.2 - 2.3e-06 28.1 0.0 6.8e-05 23.3 0.0 2.4 1 1 0 1 1 1 1 SET domain BPL_LplA_LipB PF03099.19 CAM42548.1 - 2.9e-11 43.4 0.0 6.3e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family HBS1_N PF08938.10 CAM42548.1 - 0.0098 16.2 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 1 HBS1 N-terminus CM_2 PF01817.21 CAM42548.1 - 0.21 11.9 0.0 0.53 10.7 0.0 1.6 2 0 0 2 2 2 0 Chorismate mutase type II Apolipoprotein PF01442.18 CAM42549.2 - 0.012 15.5 11.3 0.02 14.8 11.3 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Trimer_CC PF08954.11 CAM42549.2 - 0.019 14.5 0.5 0.079 12.5 0.5 2.1 1 0 0 1 1 1 0 Trimerisation motif OmpH PF03938.14 CAM42549.2 - 0.043 14.1 1.2 0.082 13.2 1.2 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Nup54 PF13874.6 CAM42549.2 - 0.1 12.7 1.9 0.23 11.6 1.9 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 FAM76 PF16046.5 CAM42549.2 - 1.7 8.0 3.6 2.4 7.5 3.6 1.1 1 0 0 1 1 1 0 FAM76 protein ABC_tran_CTD PF16326.5 CAM42549.2 - 1.9 8.8 4.8 7 7.0 0.8 2.5 1 1 0 2 2 2 0 ABC transporter C-terminal domain DUF4407 PF14362.6 CAM42549.2 - 3.9 6.8 5.5 6.2 6.1 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CLZ PF16526.5 CAM42549.2 - 4.5 7.7 5.7 17 5.8 2.4 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TMPIT PF07851.13 CAM42549.2 - 5.5 6.1 5.6 7.7 5.7 5.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF4498 PF14926.6 CAM42550.1 - 7e-15 55.0 0.0 5.9e-12 45.4 0.0 3.0 2 1 0 2 2 2 2 Domain of unknown function (DUF4498) EMP24_GP25L PF01105.24 CAM42551.1 - 5.1e-24 85.2 0.0 5.8e-24 85.0 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Gypsy PF07253.11 CAM42551.1 - 0.06 11.9 0.2 0.072 11.6 0.2 1.1 1 0 0 1 1 1 0 Gypsy protein EMP24_GP25L PF01105.24 CAM42552.1 - 5.9e-23 81.7 0.1 6.4e-23 81.6 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD LigT_PEase PF02834.16 CAM42552.1 - 0.081 13.1 0.0 0.19 11.9 0.0 1.8 1 1 0 1 1 1 0 LigT like Phosphoesterase DUF192 PF02643.15 CAM42552.1 - 0.13 12.4 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized ACR, COG1430 Peptidase_M20 PF01546.28 CAM42553.1 - 9.3e-27 94.1 0.1 1.2e-26 93.7 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CAM42553.1 - 2.1e-08 34.1 0.0 5.2e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Hydrolase_4 PF12146.8 CAM42554.1 - 2.5e-68 229.9 0.0 3.3e-68 229.5 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CAM42554.1 - 6.8e-16 58.7 0.1 6.1e-13 49.0 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CAM42554.1 - 5.5e-13 50.0 0.1 7.4e-13 49.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CAM42554.1 - 1.3e-10 41.1 0.2 1.4e-05 24.7 0.1 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 CAM42554.1 - 2.9e-05 23.8 0.1 0.0025 17.5 0.0 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DUF2920 PF11144.8 CAM42554.1 - 0.00014 21.2 0.0 0.062 12.5 0.0 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2920) DLH PF01738.18 CAM42554.1 - 0.0012 18.4 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family PGAP1 PF07819.13 CAM42554.1 - 0.0027 17.5 0.0 0.0037 17.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 CAM42554.1 - 0.0031 17.4 0.0 0.0045 16.9 0.0 1.3 1 1 0 1 1 1 1 Palmitoyl protein thioesterase PhoPQ_related PF10142.9 CAM42554.1 - 0.0059 15.3 0.0 0.0077 14.9 0.0 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Abhydrolase_8 PF06259.12 CAM42554.1 - 0.0098 15.5 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase Esterase PF00756.20 CAM42554.1 - 0.012 15.2 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Ser_hydrolase PF06821.13 CAM42554.1 - 0.033 14.0 0.0 1 9.2 0.0 2.2 1 1 0 1 1 1 0 Serine hydrolase Abhydrolase_3 PF07859.13 CAM42554.1 - 0.066 13.1 0.0 0.11 12.4 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 CAM42554.1 - 0.1 12.4 0.1 1.1 9.0 0.0 2.3 3 0 0 3 3 3 0 Alpha/beta hydrolase family Thioesterase PF00975.20 CAM42554.1 - 0.15 12.1 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain LRR_4 PF12799.7 CAM42556.2 - 2.5e-11 43.6 17.8 0.057 13.9 0.0 7.9 5 2 3 9 9 9 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM42556.2 - 4.1e-05 23.3 11.9 0.041 13.7 0.2 5.5 6 1 0 6 6 6 3 Leucine rich repeat LRR_9 PF14580.6 CAM42556.2 - 0.0079 15.7 2.3 1.5 8.3 0.4 3.7 2 2 1 4 4 4 2 Leucine-rich repeat Cyt-b5 PF00173.28 CAM42557.1 - 1.8e-05 24.8 0.0 3.2e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cyt-b5 PF00173.28 CAM42558.1 - 1.1e-07 31.8 0.0 1.6e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4335 PF14233.6 CAM42558.1 - 0.008 16.1 0.3 0.014 15.4 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4335) Cyt-b5 PF00173.28 CAM42559.1 - 1.4e-06 28.4 0.0 1.8e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Rib_recp_KP_reg PF05104.12 CAM42559.1 - 0.55 11.3 10.6 0.69 10.9 10.6 1.1 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region Cyt-b5 PF00173.28 CAM42560.1 - 2.6e-08 33.9 0.0 3.4e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cyt-b5 PF00173.28 CAM42561.1 - 1.3e-08 34.9 0.0 1.8e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cyt-b5 PF00173.28 CAM42562.1 - 2e-08 34.3 0.0 2.5e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Fanconi_A_N PF15865.5 CAM42562.1 - 0.11 11.9 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Fanconi anaemia group A protein N terminus Cyt-b5 PF00173.28 CAM42563.1 - 1.3e-08 34.9 0.0 1.8e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3638 PF12340.8 CAM42564.2 - 4.6e-29 101.4 0.0 4.7e-28 98.1 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 CAM42564.2 - 8.3e-16 57.1 0.5 2.7e-15 55.4 0.5 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) zf-RanBP PF00641.18 CAM42564.2 - 2.3e-07 30.0 22.3 4.1e-05 22.8 5.3 3.6 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others Thioredoxin_8 PF13905.6 CAM42564.2 - 1.4e-06 28.5 0.0 3.4e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like ubiquitin PF00240.23 CAM42564.2 - 0.0012 18.5 0.0 0.0028 17.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family TMEM51 PF15345.6 CAM42564.2 - 0.2 11.5 0.0 0.2 11.5 0.0 2.3 2 0 0 2 2 2 0 Transmembrane protein 51 H_PPase PF03030.16 CAM42565.1 - 3.3e-238 792.6 28.1 3.3e-238 792.6 28.1 1.4 1 1 0 1 1 1 1 Inorganic H+ pyrophosphatase RP853 PF17542.2 CAM42565.1 - 5 6.1 6.0 8.9 5.3 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized RP853 GAIN PF16489.5 CAM42566.1 - 0.0058 16.1 0.1 0.012 15.1 0.1 1.5 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain PilA4 PF18682.1 CAM42566.1 - 0.7 10.3 3.0 0.45 10.9 0.6 1.9 2 0 0 2 2 2 0 Pilin A4 LRR_6 PF13516.6 CAM42566.1 - 1.4 9.2 7.9 6.9 7.0 0.1 4.5 4 0 0 4 4 4 0 Leucine Rich repeat LRR_8 PF13855.6 CAM42566.1 - 3.8 7.4 6.5 25 4.7 4.1 3.3 1 1 1 2 2 2 0 Leucine rich repeat HTH_23 PF13384.6 CAM42567.2 - 0.031 14.1 0.1 0.1 12.4 0.1 2.0 2 0 0 2 2 2 0 Homeodomain-like domain RILP PF11461.8 CAM42568.1 - 0.12 12.7 8.4 1.6 9.0 1.7 3.6 2 0 0 2 2 2 0 Rab interacting lysosomal protein MT PF12777.7 CAM42569.1 - 4e-06 26.1 0.1 4e-06 26.1 0.1 2.2 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor DUF4407 PF14362.6 CAM42569.1 - 0.026 13.9 25.5 0.1 11.9 14.9 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) DDE_Tnp_ISL3 PF01610.17 CAM42569.1 - 0.027 14.2 1.0 0.071 12.8 1.0 1.6 1 0 0 1 1 1 0 Transposase GramPos_pilinD1 PF16555.5 CAM42569.1 - 0.41 10.8 2.2 1.1 9.4 2.2 1.8 1 0 0 1 1 1 0 Gram-positive pilin subunit D1, N-terminal domain ORF6C PF10552.9 CAM42569.1 - 0.96 9.5 4.0 3.2 7.9 1.9 2.5 2 0 0 2 2 2 0 ORF6C domain Con-6 PF10346.9 CAM42569.1 - 1.9 8.6 0.0 1.9 8.6 0.0 3.9 5 0 0 5 5 5 0 Conidiation protein 6 Rx_N PF18052.1 CAM42569.1 - 7.4 6.9 9.2 0.63 10.4 0.5 3.4 4 0 0 4 4 4 0 Rx N-terminal domain PRKG1_interact PF15898.5 CAM42569.1 - 9.6 7.2 19.8 4.4 8.3 0.7 4.1 3 1 1 4 4 4 0 cGMP-dependent protein kinase interacting domain ABC_membrane PF00664.23 CAM42570.1 - 1.7e-49 168.9 28.7 6e-27 95.0 11.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CAM42570.1 - 1.9e-46 158.0 0.0 1.3e-23 84.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 CAM42570.1 - 3.1e-10 39.7 1.9 1.3e-05 24.9 0.1 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain SMC_N PF02463.19 CAM42570.1 - 3.2e-09 36.5 0.0 0.048 13.1 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CAM42570.1 - 5e-09 36.4 0.0 0.0034 17.3 0.0 4.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CAM42570.1 - 1.1e-07 32.5 0.0 0.00018 22.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 CAM42570.1 - 4.9e-07 29.1 0.0 0.01 14.9 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.6 CAM42570.1 - 3.3e-06 27.6 0.7 0.0044 17.4 0.1 2.9 2 1 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 CAM42570.1 - 1.6e-05 24.4 0.2 0.018 14.4 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 CAM42570.1 - 1.9e-05 24.7 0.1 0.25 11.4 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CAM42570.1 - 9.7e-05 22.3 0.1 0.011 15.7 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 CAM42570.1 - 0.00011 22.4 0.8 0.018 15.1 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA_25 PF13481.6 CAM42570.1 - 0.0002 21.0 0.7 0.023 14.3 0.1 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 CAM42570.1 - 0.00036 20.7 0.8 0.66 10.0 0.1 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_22 PF13401.6 CAM42570.1 - 0.00038 20.7 1.8 0.26 11.6 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 CAM42570.1 - 0.00039 20.2 0.1 0.3 10.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CAM42570.1 - 0.001 19.0 0.6 0.16 11.9 0.0 2.6 2 0 0 2 2 2 1 NACHT domain MeaB PF03308.16 CAM42570.1 - 0.001 18.1 0.4 0.92 8.4 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB LapA_dom PF06305.11 CAM42570.1 - 0.0037 17.1 8.0 0.68 9.8 0.0 4.4 3 0 0 3 3 3 1 Lipopolysaccharide assembly protein A domain TrwB_AAD_bind PF10412.9 CAM42570.1 - 0.018 14.0 0.3 0.71 8.7 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.6 CAM42570.1 - 0.021 14.6 0.0 0.95 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 CAM42570.1 - 0.026 14.3 0.7 5.8 6.6 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein cobW PF02492.19 CAM42570.1 - 0.032 13.8 3.4 0.95 9.0 0.2 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 CAM42570.1 - 0.039 14.4 0.1 2.3 8.6 0.0 3.1 3 0 0 3 3 3 0 RNA helicase AAA_33 PF13671.6 CAM42570.1 - 0.043 14.0 1.9 0.94 9.6 0.2 2.8 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 CAM42570.1 - 0.05 13.3 0.1 6.1 6.5 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 CAM42570.1 - 0.079 13.0 0.1 11 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CAM42570.1 - 0.11 13.0 0.2 6.6 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CAM42570.1 - 0.13 11.7 0.1 17 4.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region Adeno_IVa2 PF02456.15 CAM42570.1 - 0.15 10.8 0.6 0.57 8.9 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein MobB PF03205.14 CAM42570.1 - 0.16 11.9 0.1 20 5.1 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 CAM42570.1 - 0.22 11.4 0.7 28 4.6 0.0 2.8 3 0 0 3 3 3 0 NTPase ABC_tran PF00005.27 CAM42571.1 - 9.1e-47 159.0 0.0 1.2e-23 84.2 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 CAM42571.1 - 2.8e-43 148.6 19.8 4.4e-26 92.2 7.8 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_29 PF13555.6 CAM42571.1 - 2.3e-10 40.1 0.2 1.1e-05 25.1 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 CAM42571.1 - 3.9e-09 36.3 0.7 0.049 13.1 0.0 4.2 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CAM42571.1 - 1e-08 35.4 0.0 0.0031 17.4 0.0 4.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CAM42571.1 - 1.2e-07 32.5 0.0 0.00015 22.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 CAM42571.1 - 4.8e-07 29.1 0.0 0.016 14.3 0.1 2.6 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_16 PF13191.6 CAM42571.1 - 7.1e-06 26.5 2.2 0.0064 16.9 0.1 3.2 3 0 0 3 3 3 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 CAM42571.1 - 1.3e-05 24.7 0.2 0.015 14.6 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 CAM42571.1 - 1.6e-05 24.9 0.0 0.23 11.6 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CAM42571.1 - 8.4e-05 22.5 0.1 0.011 15.6 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 CAM42571.1 - 8.8e-05 22.6 1.1 0.016 15.2 0.0 2.6 3 0 0 3 3 2 1 Dynamin family AAA_25 PF13481.6 CAM42571.1 - 0.00015 21.4 1.2 0.021 14.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 CAM42571.1 - 0.00028 20.7 0.2 0.28 10.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.17 CAM42571.1 - 0.00028 21.1 0.6 0.6 10.2 0.1 2.3 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_22 PF13401.6 CAM42571.1 - 0.00029 21.1 1.8 0.23 11.7 0.0 3.1 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 CAM42571.1 - 0.00093 19.1 0.6 0.14 12.0 0.0 2.5 2 0 0 2 2 2 1 NACHT domain MeaB PF03308.16 CAM42571.1 - 0.00095 18.2 0.6 0.79 8.7 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 CAM42571.1 - 0.02 14.7 0.0 0.86 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CAM42571.1 - 0.022 15.1 0.1 2.1 8.8 0.0 3.4 4 0 0 4 4 3 0 RNA helicase TrwB_AAD_bind PF10412.9 CAM42571.1 - 0.025 13.5 0.6 0.65 8.9 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ATP_bind_1 PF03029.17 CAM42571.1 - 0.025 14.4 0.7 5.3 6.7 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein cobW PF02492.19 CAM42571.1 - 0.029 13.9 3.4 0.87 9.1 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 CAM42571.1 - 0.035 14.3 1.9 0.86 9.8 0.2 2.8 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 CAM42571.1 - 0.04 13.6 0.1 5.6 6.6 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 CAM42571.1 - 0.044 13.7 1.8 26 4.7 0.0 3.6 3 1 1 4 4 4 0 NTPase AAA_5 PF07728.14 CAM42571.1 - 0.069 13.1 0.1 10 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CAM42571.1 - 0.11 13.0 0.1 6 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CAM42571.1 - 0.14 11.7 0.1 17 4.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region MobB PF03205.14 CAM42571.1 - 0.14 12.0 0.1 18 5.2 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Adeno_IVa2 PF02456.15 CAM42571.1 - 0.15 10.9 0.8 0.54 9.0 0.1 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_27 PF13514.6 CAM42571.1 - 0.18 11.4 0.0 0.8 9.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 CAM42571.1 - 0.54 10.5 1.3 27 5.0 0.1 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ABC_ATPase PF09818.9 CAM42571.1 - 0.77 8.5 2.8 0.8 8.4 0.1 2.2 3 0 0 3 3 3 0 Predicted ATPase of the ABC class CAP_GLY PF01302.25 CAM42572.2 - 0.0053 16.8 0.7 0.048 13.7 0.4 2.3 2 0 0 2 2 2 1 CAP-Gly domain zf-LSD1 PF06943.12 CAM42575.1 - 1.4e-10 40.8 7.3 1.4e-10 40.8 7.3 2.4 2 0 0 2 2 2 1 LSD1 zinc finger zinc-ribbons_6 PF07191.12 CAM42575.1 - 0.15 12.1 10.5 0.71 9.9 7.3 2.1 2 0 0 2 2 2 0 zinc-ribbons DZR PF12773.7 CAM42575.1 - 0.16 12.1 14.9 1.8 8.7 8.2 2.3 1 1 1 2 2 2 0 Double zinc ribbon Tmemb_55A PF09788.9 CAM42575.1 - 0.63 9.1 13.5 3.9 6.5 13.5 1.9 1 1 0 1 1 1 0 Transmembrane protein 55A zinc_ribbon_4 PF13717.6 CAM42575.1 - 1.1 9.3 0.0 1.1 9.3 0.0 3.9 3 1 1 4 4 3 0 zinc-ribbon domain zinc_ribbon_9 PF14369.6 CAM42575.1 - 3.3 8.1 16.4 3.1 8.1 1.8 2.9 1 1 2 3 3 3 0 zinc-ribbon OrfB_Zn_ribbon PF07282.11 CAM42575.1 - 3.3 7.7 10.0 3 7.8 2.2 2.4 1 1 2 3 3 3 0 Putative transposase DNA-binding domain HypA PF01155.19 CAM42575.1 - 6.6 6.8 11.3 2.1 8.4 0.7 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Sirohm_synth_M PF14824.6 CAM42576.1 - 0.033 13.7 0.0 0.073 12.5 0.0 1.6 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central CSD PF00313.22 CAM42577.1 - 5.4e-10 39.0 0.1 7.6e-07 28.9 0.0 2.5 2 0 0 2 2 2 2 'Cold-shock' DNA-binding domain DUF4530 PF15039.6 CAM42577.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) CSD PF00313.22 CAM42578.2 - 0.00055 19.7 0.0 1.9 8.4 0.0 3.2 2 1 1 3 3 3 2 'Cold-shock' DNA-binding domain DUF5527 PF17665.1 CAM42579.1 - 0.021 14.4 0.5 0.17 11.4 0.1 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5527) Fib_alpha PF08702.10 CAM42579.1 - 5.2 7.2 11.4 8.5 6.6 0.1 2.8 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DivIC PF04977.15 CAM42579.1 - 6.1 6.7 25.1 1.6 8.5 0.3 4.7 4 2 0 4 4 4 0 Septum formation initiator YabA PF06156.13 CAM42579.1 - 6.3 7.5 17.7 18 6.1 0.7 3.9 2 1 1 3 3 3 0 Initiation control protein YabA SPRY PF00622.28 CAM42580.1 - 1.1e-05 25.5 0.0 2.7e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 SPRY domain HAP1_N PF04849.13 CAM42580.1 - 0.00072 18.9 18.4 0.00072 18.9 18.4 3.9 2 2 2 4 4 4 2 HAP1 N-terminal conserved region ATG16 PF08614.11 CAM42580.1 - 0.0069 16.6 15.9 0.0069 16.6 15.9 4.7 1 1 3 4 4 4 1 Autophagy protein 16 (ATG16) Neuralized PF07177.12 CAM42580.1 - 0.014 15.4 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 Neuralized DUF503 PF04456.12 CAM42580.1 - 0.054 13.3 0.7 0.55 10.1 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF503) DUF1388 PF07142.12 CAM42580.1 - 0.87 9.6 5.0 0.44 10.6 2.3 2.0 2 0 0 2 2 2 0 Repeat of unknown function (DUF1388) ABC_tran PF00005.27 CAM42585.2 - 6.3e-45 153.0 0.0 5.3e-27 95.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CAM42585.2 - 1.8e-40 139.3 18.4 8.6e-21 74.8 4.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 CAM42585.2 - 2.8e-09 36.8 0.0 0.041 13.3 0.0 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CAM42585.2 - 1.8e-07 31.3 0.0 0.0093 15.8 0.0 3.5 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 CAM42585.2 - 9.9e-07 28.1 0.0 0.039 13.0 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 CAM42585.2 - 1.8e-06 27.6 0.2 0.096 12.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 CAM42585.2 - 2.1e-05 24.0 0.2 0.05 13.0 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_16 PF13191.6 CAM42585.2 - 3.3e-05 24.3 0.2 0.14 12.5 0.0 3.1 3 0 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 CAM42585.2 - 0.00011 22.5 0.6 0.2 11.9 0.1 3.0 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 CAM42585.2 - 0.00013 22.0 0.1 0.077 13.1 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 CAM42585.2 - 0.0007 20.2 0.0 0.99 9.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain TrwB_AAD_bind PF10412.9 CAM42585.2 - 0.0036 16.3 0.2 2.3 7.1 0.0 2.2 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain RsgA_GTPase PF03193.16 CAM42585.2 - 0.0043 17.0 0.3 1.2 9.0 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 CAM42585.2 - 0.0053 16.4 0.3 4.1 6.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CAM42585.2 - 0.007 16.1 0.2 5.9 6.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 CAM42585.2 - 0.008 16.3 5.2 0.23 11.5 0.2 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain ATP-synt_ab PF00006.25 CAM42585.2 - 0.0099 15.5 0.1 0.4 10.3 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Ploopntkinase3 PF18751.1 CAM42585.2 - 0.02 14.8 0.3 0.92 9.4 0.0 2.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 MeaB PF03308.16 CAM42585.2 - 0.034 13.1 1.4 4.9 6.1 0.1 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 CAM42585.2 - 0.038 13.9 1.2 4.2 7.3 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 CAM42585.2 - 0.092 12.9 0.9 9 6.4 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CAM42585.2 - 0.14 11.7 0.1 10 5.6 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_5 PF07728.14 CAM42585.2 - 0.15 12.1 0.2 9.9 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) cobW PF02492.19 CAM42585.2 - 0.15 11.7 2.9 7.1 6.2 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.12 CAM42585.2 - 0.15 11.5 0.8 7.4 5.9 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein USP8_interact PF08941.10 CAM42585.2 - 0.2 11.4 0.0 0.41 10.4 0.0 1.4 1 0 0 1 1 1 0 USP8 interacting AAA_19 PF13245.6 CAM42585.2 - 0.22 11.9 1.3 38 4.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.9 CAM42585.2 - 0.24 10.6 0.6 1.9 7.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Dynamin_N PF00350.23 CAM42585.2 - 0.27 11.3 2.8 5.4 7.0 0.3 2.3 2 0 0 2 2 2 0 Dynamin family CbiA PF01656.23 CAM42585.2 - 0.86 9.7 2.1 46 4.1 0.6 2.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain LRR_8 PF13855.6 CAM42586.1 - 1.5e-09 37.5 0.0 0.00013 21.7 0.0 3.1 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 CAM42586.1 - 0.002 18.5 0.0 0.028 14.8 0.0 2.5 2 1 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM42587.1 - 4.8e-09 35.9 0.0 0.00017 21.3 0.0 3.1 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 CAM42587.1 - 0.0027 18.1 0.0 0.036 14.5 0.0 2.5 2 1 0 2 2 2 1 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 CAM42587.1 - 0.044 14.1 0.2 0.044 14.1 0.2 2.7 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain LRR_8 PF13855.6 CAM42588.1 - 4.1e-05 23.2 0.1 0.21 11.4 0.5 3.1 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 CAM42588.1 - 0.022 15.2 0.3 14 6.3 0.8 4.0 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) Kei1 PF08552.11 CAM42589.2 - 0.21 11.4 0.0 0.4 10.5 0.0 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 LRR_4 PF12799.7 CAM42590.2 - 1.7e-15 56.9 2.8 1 9.9 0.0 10.3 8 2 1 11 11 11 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CAM42590.2 - 1.2e-08 34.3 8.5 0.54 10.4 0.2 9.8 11 0 0 11 11 11 2 Leucine Rich repeat LRR_8 PF13855.6 CAM42590.2 - 0.00013 21.6 11.0 0.41 10.5 0.0 7.4 7 0 0 7 7 7 1 Leucine rich repeat HEAT_2 PF13646.6 CAM42590.2 - 0.071 13.5 0.0 0.22 11.9 0.0 1.8 1 0 0 1 1 1 0 HEAT repeats Acyl-CoA_dh_2 PF08028.11 CAM42591.1 - 0.094 13.0 10.7 0.091 13.0 1.4 3.1 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase, C-terminal domain Y_phosphatase3 PF13350.6 CAM42593.1 - 0.22 11.5 0.1 0.34 10.8 0.1 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Pkinase PF00069.25 CAM42594.1 - 3.9e-40 137.9 0.0 3.3e-28 98.8 0.0 2.5 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM42594.1 - 2.1e-20 73.1 0.0 9.7e-19 67.7 0.0 2.7 2 1 0 2 2 2 1 Protein tyrosine kinase PH_3 PF14593.6 CAM42594.1 - 0.00023 21.2 0.0 0.00061 19.9 0.0 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 CAM42594.1 - 0.058 12.7 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like L51_S25_CI-B8 PF05047.16 CAM42596.1 - 1e-08 35.0 0.1 3.3e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain LysR_substrate PF03466.20 CAM42596.1 - 0.027 13.8 0.6 0.58 9.5 0.0 2.2 2 0 0 2 2 2 0 LysR substrate binding domain Cmc1 PF08583.10 CAM42599.1 - 0.053 13.5 2.6 0.11 12.6 2.6 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Ribosomal_L36 PF00444.18 CAM42600.1 - 0.00022 21.3 1.6 0.0005 20.2 1.6 1.6 1 0 0 1 1 1 1 Ribosomal protein L36 TP_methylase PF00590.20 CAM42602.1 - 5.6e-21 75.5 0.0 9.9e-21 74.7 0.0 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF4434 PF14488.6 CAM42602.1 - 0.023 14.7 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) NTPase_I-T PF01931.18 CAM42603.1 - 3.3e-53 179.8 0.1 3.7e-53 179.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 Thiolase_N PF00108.23 CAM42604.1 - 7.7e-58 195.9 0.7 1.4e-57 195.1 0.7 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CAM42604.1 - 2.8e-33 114.2 0.0 8.3e-33 112.7 0.0 1.9 1 0 0 1 1 1 1 Thiolase, C-terminal domain SpoVAD PF07451.11 CAM42604.1 - 7.3e-05 21.6 0.1 0.00015 20.6 0.1 1.4 1 0 0 1 1 1 1 Stage V sporulation protein AD (SpoVAD) ketoacyl-synt PF00109.26 CAM42604.1 - 0.00012 21.7 3.7 0.00023 20.8 3.2 1.8 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain FAE1_CUT1_RppA PF08392.12 CAM42604.1 - 0.0016 17.8 0.1 0.003 16.9 0.1 1.3 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III PF08545.10 CAM42604.1 - 0.2 11.5 2.2 6 6.8 0.8 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III LRR_4 PF12799.7 CAM42605.1 - 1.2e-12 47.8 14.5 0.2 12.1 0.2 7.1 6 1 1 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM42605.1 - 0.0027 17.4 11.8 4.3 7.2 0.1 5.4 3 2 4 7 7 7 4 Leucine rich repeat Phage_integrase PF00589.22 CAM42606.1 - 5.6e-07 29.5 0.0 4.1e-06 26.7 0.0 2.5 2 0 0 2 2 2 1 Phage integrase family RVT_1 PF00078.27 CAM42606.1 - 0.0023 17.5 0.0 0.0061 16.1 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A17 PF05380.13 CAM42606.1 - 0.0034 17.4 0.1 0.044 13.8 0.0 2.4 1 1 1 2 2 2 1 Pao retrotransposon peptidase zf-MYND PF01753.18 CAM42607.1 - 6.4e-11 42.2 9.6 6.4e-11 42.2 9.6 1.9 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 CAM42607.1 - 0.00021 21.5 11.8 0.00047 20.4 11.8 1.7 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 CAM42607.1 - 0.53 10.4 7.6 1.4 9.1 7.6 1.7 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 CAM42608.1 - 1.6e-10 40.9 9.6 1.6e-10 40.9 9.6 2.1 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 CAM42608.1 - 0.00072 19.8 12.3 0.0019 18.4 12.3 1.7 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 CAM42608.1 - 0.34 11.0 5.7 0.94 9.6 5.7 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Sld5 PF05916.11 CAM42609.1 - 3.1e-09 37.3 0.0 4.1e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein GlgS PF08971.11 CAM42611.1 - 0.036 14.1 0.1 0.07 13.2 0.1 1.4 1 0 0 1 1 1 0 Glycogen synthesis protein CLIP1_ZNF PF16641.5 CAM42611.1 - 0.13 12.2 1.5 0.34 10.8 1.5 1.8 1 0 0 1 1 1 0 CLIP1 zinc knuckle DUF1682 PF07946.14 CAM42611.1 - 0.45 9.7 6.9 0.75 8.9 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Anophelin PF10731.9 CAM42612.2 - 0.078 12.8 0.1 1.5 8.7 0.1 2.7 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito UME PF08064.13 CAM42612.2 - 0.12 12.3 1.3 0.48 10.4 0.2 2.7 2 0 0 2 2 2 0 UME (NUC010) domain PPR_3 PF13812.6 CAM42613.1 - 0.067 13.3 0.3 2.3 8.4 0.0 2.8 3 0 0 3 3 3 0 Pentatricopeptide repeat domain PPR_2 PF13041.6 CAM42613.1 - 0.078 13.2 0.3 1.3e+02 2.9 0.0 4.1 5 0 0 5 5 5 0 PPR repeat family CSTF1_dimer PF16699.5 CAM42614.1 - 0.28 11.0 0.6 19 5.1 0.0 3.3 3 0 0 3 3 3 0 Cleavage stimulation factor subunit 1, dimerisation domain Cullin_Nedd8 PF10557.9 CAM42615.1 - 9.9e-14 51.1 0.4 3e-13 49.6 0.3 1.9 2 0 0 2 2 2 1 Cullin protein neddylation domain Cullin PF00888.22 CAM42615.1 - 0.0019 16.9 0.1 0.03 13.0 0.1 2.3 1 1 0 1 1 1 1 Cullin family NAP PF00956.18 CAM42618.1 - 2.5e-76 256.4 0.4 2.5e-76 256.4 0.4 1.8 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) DUF2457 PF10446.9 CAM42618.1 - 0.24 10.5 21.6 0.076 12.2 12.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) BUD22 PF09073.10 CAM42618.1 - 0.26 10.6 12.4 0.47 9.8 12.4 1.4 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 CAM42618.1 - 0.36 9.0 14.6 0.5 8.5 14.6 1.1 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.10 CAM42618.1 - 0.61 10.5 28.4 2.1 8.8 17.4 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 CAM42618.1 - 0.92 9.2 24.5 0.038 13.7 7.1 2.7 2 1 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Pox_Ag35 PF03286.14 CAM42618.1 - 1.9 8.2 17.2 2 8.2 0.8 3.1 3 0 0 3 3 3 0 Pox virus Ag35 surface protein DNA_pol_phi PF04931.13 CAM42618.1 - 2 6.4 21.5 0.17 10.0 11.8 2.1 2 0 0 2 2 2 0 DNA polymerase phi RRN3 PF05327.11 CAM42618.1 - 6.9 5.1 10.5 10 4.5 10.5 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Aa_trans PF01490.18 CAM42619.1 - 7.7e-43 146.7 24.1 1e-42 146.3 24.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CAM42619.1 - 5.2e-08 32.3 10.9 5.2e-08 32.3 10.9 2.4 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Aa_trans PF01490.18 CAM42620.1 - 8.7e-42 143.3 23.4 1.1e-41 142.9 23.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CAM42620.1 - 3.4e-08 32.9 11.8 3.4e-08 32.9 11.8 2.3 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family TRAM_LAG1_CLN8 PF03798.16 CAM42621.1 - 1.4e-41 142.4 19.1 1.4e-41 142.4 19.1 2.1 2 0 0 2 2 2 1 TLC domain Aa_trans PF01490.18 CAM42622.1 - 1.2e-43 149.4 22.8 1.5e-43 149.0 22.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CAM42622.1 - 3.1e-08 33.1 11.6 3.1e-08 33.1 11.6 2.3 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Cytochrom_B_C PF00032.17 CAM42622.1 - 2.1 8.7 7.3 0.2 12.0 0.3 2.9 3 0 0 3 3 3 0 Cytochrome b(C-terminal)/b6/petD DUF3235 PF11574.8 CAM42623.2 - 2.9 8.8 4.6 11 7.0 4.6 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) Aa_trans PF01490.18 CAM42624.1 - 1.2e-41 142.8 23.5 1.5e-41 142.4 23.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 CAM42624.1 - 2.9e-08 33.0 26.9 2.9e-08 33.0 26.9 2.1 2 0 0 2 2 2 1 Amino acid permease Trp_Tyr_perm PF03222.13 CAM42624.1 - 1.7e-07 30.7 10.9 1.7e-07 30.7 10.9 2.5 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Pkinase PF00069.25 CAM42625.1 - 1.5e-15 57.3 0.0 2.2e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM42625.1 - 1.7e-12 47.2 0.0 9.4e-09 34.9 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Aa_trans PF01490.18 CAM42626.1 - 6e-42 143.8 23.7 7.9e-42 143.4 23.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 CAM42626.1 - 2.8e-08 33.0 26.7 2.8e-08 33.0 26.7 2.1 2 0 0 2 2 2 1 Amino acid permease Trp_Tyr_perm PF03222.13 CAM42626.1 - 5.1e-07 29.1 10.6 5.1e-07 29.1 10.6 2.5 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Pkinase PF00069.25 CAM42628.1 - 1.2e-15 57.7 0.0 2.3e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM42628.1 - 1.6e-12 47.3 0.0 6.7e-12 45.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3235 PF11574.8 CAM42628.1 - 5.5 7.9 5.4 21 6.1 5.4 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) Glycos_transf_1 PF00534.20 CAM42629.2 - 3.3e-11 43.0 0.0 9.1e-11 41.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CAM42629.2 - 9e-11 42.3 0.1 7.1e-10 39.4 0.0 2.5 1 1 1 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CAM42629.2 - 7.5e-05 23.0 0.0 0.00034 20.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CAM42629.2 - 0.0003 20.8 0.1 0.00083 19.4 0.1 1.8 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_transf_90 PF05686.12 CAM42629.2 - 0.0027 16.7 0.1 0.0077 15.2 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 90 Peptidase_M20 PF01546.28 CAM42630.1 - 2.4e-20 73.1 0.1 3.3e-20 72.7 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CAM42630.1 - 1.2e-08 34.8 0.0 2.5e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain ubiquitin PF00240.23 CAM42631.1 - 7.7e-33 112.1 0.3 1e-32 111.7 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 CAM42631.1 - 2.4e-27 94.6 10.7 3.6e-27 94.0 10.7 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 CAM42631.1 - 1.9e-16 59.7 0.3 2.7e-16 59.2 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CAM42631.1 - 6.7e-05 23.3 0.1 0.00029 21.2 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 CAM42631.1 - 0.0021 18.4 0.1 0.0042 17.4 0.1 1.5 2 0 0 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CAM42631.1 - 0.0047 16.8 0.0 0.006 16.5 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CAM42631.1 - 0.014 15.5 0.1 0.027 14.6 0.1 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CAM42631.1 - 0.03 14.4 1.1 4.1 7.5 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 CAM42631.1 - 0.1 13.2 0.0 0.12 12.9 0.0 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain UPF0547 PF10571.9 CAM42631.1 - 3.3 7.9 6.3 5.2 7.2 6.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 Peptidase_M20 PF01546.28 CAM42632.1 - 2.4e-20 73.1 0.1 3.3e-20 72.7 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CAM42632.1 - 1.2e-08 34.8 0.0 2.5e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain ubiquitin PF00240.23 CAM42633.1 - 7.7e-33 112.1 0.3 1e-32 111.7 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 CAM42633.1 - 2.4e-27 94.6 10.7 3.6e-27 94.0 10.7 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 CAM42633.1 - 1.9e-16 59.7 0.3 2.7e-16 59.2 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CAM42633.1 - 6.7e-05 23.3 0.1 0.00029 21.2 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 CAM42633.1 - 0.0021 18.4 0.1 0.0042 17.4 0.1 1.5 2 0 0 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CAM42633.1 - 0.0047 16.8 0.0 0.006 16.5 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CAM42633.1 - 0.014 15.5 0.1 0.027 14.6 0.1 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CAM42633.1 - 0.03 14.4 1.1 4.1 7.5 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 CAM42633.1 - 0.1 13.2 0.0 0.12 12.9 0.0 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain UPF0547 PF10571.9 CAM42633.1 - 3.3 7.9 6.3 5.2 7.2 6.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 DUF630 PF04783.12 CAM42634.1 - 0.12 12.6 0.6 0.49 10.6 0.6 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF630) RINGv PF12906.7 CAM42635.1 - 5.7e-12 45.6 6.0 5.7e-12 45.6 6.0 2.4 2 0 0 2 2 2 1 RING-variant domain DUF996 PF06195.13 CAM42635.1 - 0.091 13.1 2.0 0.19 12.0 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF996) DUF4010 PF13194.6 CAM42635.1 - 0.72 9.5 3.9 1.6 8.4 3.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) 2TM PF13239.6 CAM42635.1 - 8.3 6.8 5.8 1.6 9.1 2.0 1.8 2 0 0 2 2 2 0 2TM domain Dus PF01207.17 CAM42636.2 - 2.3e-52 178.0 0.4 6.2e-21 74.8 0.0 4.2 4 0 0 4 4 4 4 Dihydrouridine synthase (Dus) Thioredoxin_8 PF13905.6 CAM42639.1 - 5.6e-25 87.5 0.1 8.3e-25 87.0 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 CAM42639.1 - 8.2e-10 38.6 0.0 3.4e-08 33.4 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Redoxin PF08534.10 CAM42639.1 - 2.1e-09 37.3 0.0 2.9e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 CAM42639.1 - 4.5e-07 29.8 0.0 5.7e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 CAM42639.1 - 1e-05 25.9 0.0 1.6e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 CAM42639.1 - 6.6e-05 22.8 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 CAM42639.1 - 0.00084 19.5 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 CAM42639.1 - 0.0013 18.5 0.0 0.0044 16.8 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.24 CAM42639.1 - 0.0037 17.4 0.1 0.086 13.1 0.0 2.3 2 0 0 2 2 2 1 Glutaredoxin DUF953 PF06110.11 CAM42639.1 - 0.042 13.5 0.0 1.5 8.4 0.0 2.1 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.20 CAM42641.1 - 0.12 12.4 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Redoxin PF08534.10 CAM42641.1 - 0.16 11.7 0.0 0.16 11.7 0.0 1.0 1 0 0 1 1 1 0 Redoxin Peptidase_M8 PF01457.16 CAM42643.1 - 8.3e-43 146.9 0.0 9.8e-43 146.6 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin Anti-TRAP PF15777.5 CAM42643.1 - 0.19 11.7 0.0 0.66 10.0 0.0 1.8 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Peptidase_M8 PF01457.16 CAM42644.1 - 5.5e-67 226.7 0.3 6.3e-67 226.4 0.3 1.0 1 0 0 1 1 1 1 Leishmanolysin SfsA_N PF17746.1 CAM42644.1 - 0.07 13.3 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 SfsA N-terminal OB domain Peptidase_M8 PF01457.16 CAM42646.1 - 1.4e-128 429.9 0.0 3.3e-128 428.7 0.0 1.4 1 1 0 1 1 1 1 Leishmanolysin SfsA_N PF17746.1 CAM42646.1 - 0.17 12.1 0.1 0.38 10.9 0.1 1.5 1 0 0 1 1 1 0 SfsA N-terminal OB domain Peptidase_M20 PF01546.28 CAM42648.1 - 4e-21 75.7 0.1 5.4e-21 75.2 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CAM42648.1 - 1.3e-08 34.7 0.0 2.7e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain ubiquitin PF00240.23 CAM42649.1 - 7.7e-33 112.1 0.3 1e-32 111.7 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 CAM42649.1 - 2.4e-27 94.6 10.7 3.6e-27 94.0 10.7 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 CAM42649.1 - 1.9e-16 59.7 0.3 2.7e-16 59.2 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CAM42649.1 - 6.7e-05 23.3 0.1 0.00029 21.2 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 CAM42649.1 - 0.0021 18.4 0.1 0.0042 17.4 0.1 1.5 2 0 0 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CAM42649.1 - 0.0047 16.8 0.0 0.006 16.5 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CAM42649.1 - 0.014 15.5 0.1 0.027 14.6 0.1 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CAM42649.1 - 0.03 14.4 1.1 4.1 7.5 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 CAM42649.1 - 0.1 13.2 0.0 0.12 12.9 0.0 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain UPF0547 PF10571.9 CAM42649.1 - 3.3 7.9 6.3 5.2 7.2 6.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 CRAL_TRIO PF00650.20 CAM42651.1 - 1.6e-44 151.4 0.0 2.7e-44 150.7 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CAM42651.1 - 0.00045 20.4 0.0 0.0009 19.4 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 CAM42652.1 - 6.2e-38 130.0 0.0 9.9e-38 129.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CAM42652.1 - 0.0036 17.5 0.0 0.0062 16.7 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CAM42652.1 - 0.0073 16.5 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO PF00650.20 CAM42653.1 - 1.2e-34 119.3 0.0 1.9e-34 118.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CAM42653.1 - 0.023 14.9 0.0 0.045 13.9 0.0 1.5 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain SR-25 PF10500.9 CAM42654.1 - 2.4 7.7 13.7 3.8 7.0 13.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein tRNA_lig_CPD PF08302.11 CAM42659.2 - 2.3e-08 33.8 0.0 1e-07 31.7 0.0 1.9 1 1 0 2 2 2 1 Fungal tRNA ligase phosphodiesterase domain ABC_tran PF00005.27 CAM42659.2 - 0.02 15.4 0.0 0.041 14.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 CAM42659.2 - 0.06 13.5 0.0 0.24 11.5 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 CAM42659.2 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Aldo_ket_red PF00248.21 CAM42661.1 - 9.4e-52 176.0 0.0 2.1e-49 168.3 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family DUF1389 PF07146.11 CAM42663.1 - 0.078 12.2 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1389) HEAT_2 PF13646.6 CAM42663.1 - 0.14 12.5 16.8 0.39 11.1 6.5 4.7 4 1 1 5 5 5 0 HEAT repeats Mic1 PF07035.12 CAM42663.1 - 0.19 11.4 4.7 0.29 10.8 0.7 2.7 2 0 0 2 2 2 0 Colon cancer-associated protein Mic1-like SARA PF11409.8 CAM42664.2 - 0.031 14.5 0.2 0.14 12.4 0.2 2.1 1 0 0 1 1 1 0 Smad anchor for receptor activation (SARA) ECH_1 PF00378.20 CAM42667.2 - 8e-43 146.6 0.0 1e-42 146.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CAM42667.2 - 9.9e-10 38.4 0.0 1.5e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CAM42669.1 - 1.2e-28 100.1 0.0 1.4e-28 99.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 CAM42669.1 - 0.061 13.3 0.3 10 6.1 0.0 2.5 2 0 0 2 2 2 0 Peptidase family S49 ECH_1 PF00378.20 CAM42672.1 - 7.4e-47 159.8 0.0 9.4e-47 159.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CAM42672.1 - 1.5e-10 41.1 0.0 2.2e-10 40.5 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_M1_N PF17900.1 CAM42673.2 - 2.4e-07 31.1 0.0 3.8e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 CAM42673.2 - 2.4e-06 27.3 0.0 4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain DA1-like PF12315.8 CAM42673.2 - 0.003 17.0 0.0 0.0065 15.9 0.0 1.5 1 0 0 1 1 1 1 Protein DA1 Arf PF00025.21 CAM42675.1 - 1.5e-74 249.2 0.1 1.8e-74 249.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CAM42675.1 - 4.4e-15 56.0 0.1 6e-15 55.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CAM42675.1 - 4e-14 52.5 0.0 4.9e-14 52.2 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CAM42675.1 - 4.1e-14 52.5 0.0 4.9e-14 52.2 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CAM42675.1 - 5.4e-12 45.5 0.4 3.2e-08 33.1 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CAM42675.1 - 1.3e-07 31.2 0.0 1.6e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CAM42675.1 - 1.9e-05 24.7 0.0 3.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CAM42675.1 - 0.0017 17.7 0.0 0.0019 17.5 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.6 CAM42675.1 - 0.091 12.9 0.1 0.12 12.6 0.1 1.4 1 1 0 1 1 1 0 AAA domain PEMT PF04191.13 CAM42676.1 - 2.1e-29 102.0 1.4 2.1e-29 102.0 1.4 1.9 3 0 0 3 3 3 1 Phospholipid methyltransferase S1-P1_nuclease PF02265.16 CAM42678.1 - 3.7e-66 223.5 0.1 4.6e-66 223.2 0.1 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease DUF4711 PF15829.5 CAM42678.1 - 0.012 15.5 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4711) Zn_dep_PLPC PF00882.18 CAM42678.1 - 0.062 13.3 0.1 0.099 12.6 0.1 1.5 1 0 0 1 1 1 0 Zinc dependent phospholipase C SNF2_N PF00176.23 CAM42679.2 - 0.0021 16.8 0.2 0.0091 14.7 0.2 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain ECH_1 PF00378.20 CAM42680.1 - 6.5e-45 153.4 0.0 8.3e-45 153.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CAM42680.1 - 1.7e-10 40.9 0.0 2.6e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Carn_acyltransf PF00755.20 CAM42681.1 - 0.11 11.1 0.0 0.11 11.1 0.0 1.0 1 0 0 1 1 1 0 Choline/Carnitine o-acyltransferase Hydrolase_6 PF13344.6 CAM42682.1 - 9.3e-20 70.6 0.0 1.9e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CAM42682.1 - 2.5e-15 56.3 0.0 5.8e-15 55.1 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like PGP_phosphatase PF09419.10 CAM42682.1 - 0.00012 21.7 0.0 0.00026 20.7 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase Hydrolase PF00702.26 CAM42682.1 - 0.0032 17.8 0.0 0.16 12.2 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CAM42682.1 - 0.069 13.2 0.0 0.88 9.6 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CAM42683.1 - 5.7e-21 74.5 0.0 8.4e-21 74.0 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Symplekin_C PF12295.8 CAM42684.1 - 5.9e-12 46.1 4.2 6e-11 42.8 0.1 3.4 3 0 0 3 3 3 2 Symplekin tight junction protein C terminal MCU PF04678.13 CAM42686.2 - 0.12 12.4 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Cation_efflux PF01545.21 CAM42688.1 - 1e-39 136.4 9.3 1.4e-39 135.9 9.3 1.2 1 0 0 1 1 1 1 Cation efflux family bZIP_C PF12498.8 CAM42692.1 - 0.063 14.3 1.5 0.22 12.5 0.2 2.2 2 0 0 2 2 2 0 Basic leucine-zipper C terminal Lipase_3 PF01764.25 CAM42695.1 - 5.6e-39 133.3 0.0 1.3e-38 132.1 0.0 1.6 1 1 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 CAM42695.1 - 4.6e-06 26.3 0.2 6e-05 22.7 0.2 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 CAM42695.1 - 0.0013 18.0 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 CAM42695.1 - 0.0099 15.6 0.1 0.11 12.2 0.1 2.1 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 CAM42695.1 - 0.032 14.8 0.0 0.043 14.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.20 CAM42695.1 - 0.075 12.7 0.1 0.36 10.4 0.0 1.9 2 0 0 2 2 2 0 Putative esterase Abhydrolase_5 PF12695.7 CAM42695.1 - 0.22 11.3 0.0 0.65 9.7 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family PRK PF00485.18 CAM42696.1 - 1.2e-41 142.7 0.0 1.4e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 CAM42696.1 - 4e-09 37.1 0.0 5.7e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CAM42696.1 - 0.0013 18.9 0.0 0.0039 17.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CAM42696.1 - 0.0052 17.3 0.0 0.0062 17.0 0.0 1.4 1 1 0 1 1 1 1 ABC transporter APS_kinase PF01583.20 CAM42696.1 - 0.008 16.1 0.2 0.77 9.6 0.1 2.3 2 0 0 2 2 2 1 Adenylylsulphate kinase KTI12 PF08433.10 CAM42696.1 - 0.025 14.1 0.1 2.9 7.3 0.0 2.0 2 0 0 2 2 2 0 Chromatin associated protein KTI12 dNK PF01712.19 CAM42696.1 - 0.033 14.0 2.1 0.44 10.4 2.1 2.1 1 1 0 1 1 1 0 Deoxynucleoside kinase RNA_helicase PF00910.22 CAM42696.1 - 0.039 14.4 0.0 0.073 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 CAM42696.1 - 0.049 14.1 1.6 6.1 7.3 0.2 2.3 2 1 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 CAM42696.1 - 0.054 12.7 0.0 0.089 12.0 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain NB-ARC PF00931.22 CAM42696.1 - 0.073 12.2 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain cobW PF02492.19 CAM42696.1 - 0.074 12.6 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 CAM42696.1 - 0.16 11.9 0.6 0.43 10.5 0.6 1.6 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 CAM42696.1 - 0.23 11.2 0.4 0.45 10.3 0.4 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain CoaE PF01121.20 CAM42696.1 - 0.36 10.5 1.6 6.6 6.4 0.4 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase Fer2 PF00111.27 CAM42697.2 - 1.6e-11 44.0 1.2 2.3e-11 43.5 1.2 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain HECT_2 PF09814.9 CAM42697.2 - 0.0096 14.8 0.2 0.011 14.6 0.2 1.1 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Fer2 PF00111.27 CAM42698.1 - 3.1e-09 36.7 2.5 4.3e-09 36.2 2.5 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NifU PF01106.17 CAM42698.1 - 0.12 12.6 0.5 0.22 11.7 0.5 1.4 1 0 0 1 1 1 0 NifU-like domain RHH_7 PF16777.5 CAM42698.1 - 0.19 12.2 0.0 0.27 11.6 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator, RHH-like, CopG Fer2 PF00111.27 CAM42699.2 - 1.7e-10 40.7 2.0 2.4e-10 40.2 2.0 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain PRK PF00485.18 CAM42701.1 - 1.5e-41 142.3 0.0 1.8e-41 142.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 CAM42701.1 - 4.2e-09 37.0 0.0 6e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CAM42701.1 - 0.0014 18.8 0.0 0.0044 17.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CAM42701.1 - 0.0051 17.3 0.1 0.0061 17.1 0.1 1.4 1 1 0 1 1 1 1 ABC transporter APS_kinase PF01583.20 CAM42701.1 - 0.0076 16.2 0.2 0.77 9.6 0.1 2.3 2 0 0 2 2 2 1 Adenylylsulphate kinase dNK PF01712.19 CAM42701.1 - 0.031 14.1 1.6 0.39 10.5 1.6 2.1 1 1 0 1 1 1 0 Deoxynucleoside kinase KTI12 PF08433.10 CAM42701.1 - 0.034 13.6 0.1 2.9 7.3 0.0 2.0 2 0 0 2 2 2 0 Chromatin associated protein KTI12 RNA_helicase PF00910.22 CAM42701.1 - 0.039 14.4 0.0 0.073 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 CAM42701.1 - 0.051 14.0 1.6 6.4 7.2 0.2 2.3 2 1 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 CAM42701.1 - 0.055 12.7 0.0 0.083 12.1 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain cobW PF02492.19 CAM42701.1 - 0.074 12.6 0.0 0.098 12.2 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 CAM42701.1 - 0.074 12.2 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain RsgA_GTPase PF03193.16 CAM42701.1 - 0.18 11.7 0.7 0.43 10.5 0.6 1.6 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 CAM42701.1 - 0.23 11.2 0.4 0.45 10.3 0.4 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain CoaE PF01121.20 CAM42701.1 - 0.35 10.5 1.7 6.6 6.4 0.4 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase Fer2 PF00111.27 CAM42702.2 - 1.6e-11 44.0 1.2 2.3e-11 43.5 1.2 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain HECT_2 PF09814.9 CAM42702.2 - 0.0096 14.8 0.2 0.011 14.6 0.2 1.1 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Fer2 PF00111.27 CAM42703.1 - 3.1e-09 36.7 2.5 4.3e-09 36.2 2.5 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NifU PF01106.17 CAM42703.1 - 0.12 12.6 0.5 0.22 11.7 0.5 1.4 1 0 0 1 1 1 0 NifU-like domain RHH_7 PF16777.5 CAM42703.1 - 0.19 12.2 0.0 0.27 11.6 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator, RHH-like, CopG Fer2 PF00111.27 CAM42704.2 - 2.8e-10 40.0 2.0 3.9e-10 39.5 2.0 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 CAM42705.1 - 3.3e-06 26.9 0.7 5.2e-06 26.3 0.7 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain PSI PF01437.25 CAM42706.1 - 0.34 11.5 8.4 0.79 10.3 8.4 1.6 1 0 0 1 1 1 0 Plexin repeat EGF_2 PF07974.13 CAM42707.1 - 0.00015 22.0 13.2 0.00015 22.0 13.2 5.2 4 1 0 4 4 4 2 EGF-like domain EGF_2 PF07974.13 CAM42708.1 - 0.00029 21.1 13.2 0.00029 21.1 13.2 5.8 5 1 0 5 5 5 2 EGF-like domain NIPSNAP PF07978.13 CAM42709.1 - 0.013 15.7 0.0 0.038 14.2 0.0 1.7 1 0 0 1 1 1 0 NIPSNAP Bep_C_terminal PF17841.1 CAM42711.2 - 0.035 14.3 0.2 0.097 12.9 0.2 1.7 1 0 0 1 1 1 0 BID domain of Bartonella effector protein (Bep) Cwf_Cwc_15 PF04889.12 CAM42711.2 - 7.4 6.2 15.6 0.89 9.2 0.3 3.2 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein UCR_hinge PF02320.16 CAM42712.1 - 7.3e-18 64.5 3.3 8.1e-18 64.4 3.3 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein TerD PF02342.18 CAM42713.2 - 3.1e-15 56.1 0.1 0.00013 21.6 0.0 3.4 3 0 0 3 3 3 3 TerD domain FXR_C1 PF16096.5 CAM42713.2 - 0.03 14.5 1.4 6.6 7.0 0.2 2.7 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 Calreticulin PF00262.18 CAM42714.2 - 2.6e-76 256.9 21.4 7.5e-55 186.3 4.8 2.3 2 1 1 3 3 3 2 Calreticulin family Laminin_G_2 PF02210.24 CAM42714.2 - 0.0038 17.8 0.2 2.5 8.7 0.1 2.3 2 0 0 2 2 2 2 Laminin G domain Laminin_G_3 PF13385.6 CAM42714.2 - 0.031 14.4 0.0 0.067 13.3 0.0 1.5 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily YtxC PF08812.11 CAM42714.2 - 0.095 12.3 1.3 0.18 11.4 1.3 1.4 1 0 0 1 1 1 0 YtxC-like family YdfA_immunity PF12127.8 CAM42714.2 - 0.31 10.1 1.2 0.46 9.5 1.2 1.2 1 0 0 1 1 1 0 SigmaW regulon antibacterial RNA_pol_Rpb1_5 PF04998.17 CAM42715.1 - 4.7e-97 324.6 0.3 7.3e-97 324.0 0.3 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 CAM42715.1 - 4.2e-94 315.4 2.2 2e-93 313.1 0.0 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 CAM42715.1 - 9.4e-70 234.1 0.6 2.3e-69 232.8 0.6 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 CAM42715.1 - 5.8e-48 163.3 0.6 1e-47 162.4 0.6 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 CAM42715.1 - 7.5e-40 136.4 0.0 1.8e-39 135.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CAM42715.1 - 5.9e-29 100.2 0.1 1.9e-28 98.6 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_7 PF04990.12 CAM42715.1 - 9.4e-23 80.7 0.8 9.4e-23 80.7 0.8 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 PspA_IM30 PF04012.12 CAM42715.1 - 0.035 13.7 1.9 0.078 12.5 1.9 1.5 1 0 0 1 1 1 0 PspA/IM30 family CRCB PF02537.15 CAM42716.2 - 4.9e-15 55.6 9.4 1e-13 51.4 1.1 3.0 2 1 1 3 3 3 2 CrcB-like protein, Camphor Resistance (CrcB) Metallophos PF00149.28 CAM42717.1 - 3.1e-37 129.0 0.3 4.1e-37 128.7 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CAM42717.1 - 8.6e-08 32.5 0.0 6.9e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Pyr_redox_2 PF07992.14 CAM42718.2 - 3e-48 164.6 0.1 4e-48 164.1 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CAM42718.2 - 7.3e-18 64.8 0.0 4.6e-17 62.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CAM42718.2 - 9.2e-15 55.0 0.5 6.4e-12 45.9 0.0 3.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CAM42718.2 - 7.3e-09 35.3 0.4 0.0011 18.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CAM42718.2 - 6.4e-08 32.4 1.2 1.4e-07 31.2 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CAM42718.2 - 5.8e-06 26.5 0.6 0.004 17.3 0.1 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CAM42718.2 - 6.1e-06 26.1 2.7 0.054 13.1 0.5 3.9 4 0 0 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 CAM42718.2 - 7.4e-06 25.3 0.0 0.00052 19.3 0.0 2.8 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 CAM42718.2 - 1.7e-05 24.1 7.9 0.00038 19.7 1.1 3.9 2 2 2 4 4 4 1 FAD binding domain FAD_binding_3 PF01494.19 CAM42718.2 - 1.9e-05 24.1 2.8 0.0025 17.1 0.2 3.0 2 1 1 3 3 3 1 FAD binding domain HI0933_like PF03486.14 CAM42718.2 - 3.8e-05 22.6 6.1 0.019 13.7 0.6 3.2 3 0 0 3 3 3 2 HI0933-like protein Thi4 PF01946.17 CAM42718.2 - 7.5e-05 22.1 0.8 0.013 14.7 0.2 2.5 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 CAM42718.2 - 9.2e-05 21.7 1.9 0.41 9.7 0.0 3.2 2 1 0 2 2 2 2 Glucose inhibited division protein A ThiF PF00899.21 CAM42718.2 - 0.00018 20.9 0.0 0.00064 19.1 0.0 1.9 2 0 0 2 2 2 1 ThiF family Lycopene_cycl PF05834.12 CAM42718.2 - 0.0017 17.5 1.3 0.54 9.2 0.4 2.5 2 1 0 2 2 2 2 Lycopene cyclase protein NAD_binding_9 PF13454.6 CAM42718.2 - 0.0032 17.5 1.5 9 6.3 0.0 3.6 4 0 0 4 4 4 0 FAD-NAD(P)-binding F420_oxidored PF03807.17 CAM42718.2 - 0.012 16.2 0.2 8.5 7.0 0.1 2.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 CAM42718.2 - 0.022 14.6 0.3 0.054 13.4 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CAM42718.2 - 0.029 13.7 0.5 3 7.1 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 CAM42718.2 - 0.086 13.1 0.5 0.37 11.1 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain Shikimate_DH PF01488.20 CAM42718.2 - 0.087 12.9 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 CAM42719.2 - 3.1e-40 138.2 0.1 4.9e-40 137.6 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CAM42719.2 - 1.7e-20 73.4 0.1 4.6e-20 71.9 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CAM42719.2 - 6.2e-17 61.9 0.3 2.5e-12 47.2 0.0 3.2 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CAM42719.2 - 1e-10 41.5 1.2 2.7e-10 40.2 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CAM42719.2 - 1.3e-08 34.5 1.3 0.00035 19.9 0.3 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CAM42719.2 - 1e-07 32.1 1.4 0.0012 19.1 0.4 2.9 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CAM42719.2 - 4.9e-06 25.9 0.6 4.9e-06 25.9 0.6 2.0 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 CAM42719.2 - 5.5e-06 25.3 3.1 1.9e-05 23.6 0.2 2.8 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.22 CAM42719.2 - 6.9e-06 25.4 3.0 0.00018 20.7 0.7 2.9 2 1 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 CAM42719.2 - 4.8e-05 22.6 0.3 0.0024 17.0 0.0 2.4 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 CAM42719.2 - 8.6e-05 22.3 10.0 0.00025 20.7 0.5 3.3 3 1 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 CAM42719.2 - 0.00048 19.4 5.9 0.0025 17.1 0.0 3.3 3 1 1 4 4 4 1 Thi4 family PALP PF00291.25 CAM42719.2 - 0.00057 19.4 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FAD_binding_3 PF01494.19 CAM42719.2 - 0.00067 19.0 2.9 0.0052 16.1 0.2 2.8 3 1 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.21 CAM42719.2 - 0.00072 18.9 0.1 0.7 9.1 0.0 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 CAM42719.2 - 0.0053 16.1 0.1 0.013 14.8 0.1 1.6 1 0 0 1 1 1 1 ThiF family NAD_binding_9 PF13454.6 CAM42719.2 - 0.012 15.6 0.2 0.96 9.4 0.0 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 CAM42719.2 - 0.022 13.9 0.0 1.1 8.4 0.0 2.5 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) FAM163 PF15069.6 CAM42722.2 - 0.12 12.8 0.0 0.12 12.8 0.0 2.8 2 1 0 2 2 2 0 FAM163 family PAM2 PF07145.15 CAM42722.2 - 0.56 10.0 5.3 0.68 9.8 3.1 2.2 2 0 0 2 2 2 0 Ataxin-2 C-terminal region SOG2 PF10428.9 CAM42722.2 - 0.87 8.7 20.9 1.5 8.0 20.9 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein HisKA_3 PF07730.13 CAM42723.2 - 0.016 15.7 1.6 0.1 13.2 1.6 2.5 1 0 0 1 1 1 0 Histidine kinase DNA_pol_A_exo1 PF01612.20 CAM42724.2 - 0.00049 19.9 0.0 0.002 17.9 0.0 1.9 2 0 0 2 2 2 1 3'-5' exonuclease MORN PF02493.20 CAM42725.2 - 2.3e-30 102.7 47.8 8.8e-09 34.8 1.2 7.8 8 0 0 8 8 8 7 MORN repeat Kinesin PF00225.23 CAM42725.2 - 2.6e-14 52.9 0.1 3.9e-13 49.0 0.1 2.2 1 1 0 1 1 1 1 Kinesin motor domain DUF3048_C PF17479.2 CAM42725.2 - 0.044 14.2 2.0 3.3 8.1 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3048) C-terminal domain LOH1CR12 PF10158.9 CAM42725.2 - 0.45 10.5 3.6 0.58 10.2 0.6 2.5 2 0 0 2 2 2 0 Tumour suppressor protein CAP59_mtransfer PF11735.8 CAM42725.2 - 2.7 7.6 9.4 1.7 8.3 0.8 2.6 2 1 0 2 2 2 0 Cryptococcal mannosyltransferase 1 Bap31 PF05529.12 CAM42726.1 - 0.001 18.9 3.4 0.0013 18.6 3.4 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region DUF4131 PF13567.6 CAM42726.1 - 0.23 11.1 1.0 0.49 10.0 0.4 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) RCC1 PF00415.18 CAM42727.1 - 1.3e-25 89.7 16.2 6.6e-12 45.9 0.0 7.3 6 2 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CAM42727.1 - 3.8e-16 58.4 15.8 0.00056 19.6 1.5 5.0 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat EMP24_GP25L PF01105.24 CAM42728.1 - 2.7e-31 108.9 0.0 3.7e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD COPIIcoated_ERV PF07970.12 CAM42729.2 - 1.9e-64 217.6 0.0 2.9e-64 217.0 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CAM42729.2 - 1.9e-25 89.1 0.1 4.8e-25 87.7 0.1 1.7 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF725 PF05267.12 CAM42730.1 - 0.078 13.0 0.2 0.14 12.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF725) RRM_1 PF00076.22 CAM42732.1 - 9.3e-12 44.6 0.0 1.9e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dysbindin PF04440.16 CAM42733.1 - 4.3 7.5 12.2 0.66 10.1 1.2 3.2 2 2 2 4 4 4 0 Dysbindin (Dystrobrevin binding protein 1) Arf PF00025.21 CAM42735.1 - 7.6e-78 259.9 0.1 8.4e-78 259.8 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CAM42735.1 - 2.6e-14 53.1 0.3 5.8e-10 38.9 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 CAM42735.1 - 3e-14 52.9 0.0 3.6e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 CAM42735.1 - 1.6e-13 50.9 0.0 2.2e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CAM42735.1 - 6.3e-13 48.6 0.0 7.2e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CAM42735.1 - 2.9e-09 36.6 0.0 3.6e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CAM42735.1 - 8.6e-05 22.6 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CAM42735.1 - 0.0091 15.3 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.6 CAM42735.1 - 0.098 12.8 0.2 0.17 12.0 0.2 1.6 1 1 0 1 1 1 0 AAA domain DUF1771 PF08590.10 CAM42737.1 - 9.4e-20 70.8 3.2 1.8e-19 69.9 3.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) KH_1 PF00013.29 CAM42737.1 - 2.2e-08 33.8 0.5 4.8e-08 32.7 0.5 1.6 1 0 0 1 1 1 1 KH domain Smr PF01713.21 CAM42737.1 - 1e-06 29.0 0.0 2.9e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Smr domain KH_2 PF07650.17 CAM42737.1 - 0.0017 18.2 0.3 0.0042 16.9 0.3 1.7 1 0 0 1 1 1 1 KH domain KN17_SH3 PF18131.1 CAM42737.1 - 0.061 13.5 0.1 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 KN17 SH3-like C-terminal domain SLS PF14611.6 CAM42737.1 - 0.14 12.0 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator Maf1 PF09174.10 CAM42738.1 - 3.1e-26 92.6 0.0 4e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Maf1 regulator Tryp_alpha_amyl PF00234.22 CAM42738.1 - 0.02 15.3 0.0 0.035 14.5 0.0 1.3 1 0 0 1 1 1 0 Protease inhibitor/seed storage/LTP family Pox_RNA_Pol_19 PF05320.12 CAM42739.1 - 2.4 8.1 6.9 0.32 10.9 0.2 2.2 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Ribosomal_L12 PF00542.19 CAM42741.1 - 1.9e-17 63.3 2.4 3.5e-17 62.5 2.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain T2SSM PF04612.12 CAM42741.1 - 0.022 14.8 0.0 0.051 13.6 0.0 1.6 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein M Pkinase PF00069.25 CAM42742.1 - 6.2e-58 196.2 0.0 1.3e-57 195.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM42742.1 - 6.3e-28 97.8 0.0 1.3e-27 96.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 CAM42742.1 - 0.0051 16.4 0.2 0.019 14.6 0.2 2.0 1 1 0 1 1 1 1 RIO1 family Pox_ser-thr_kin PF05445.11 CAM42742.1 - 0.09 11.7 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase L71 PF02448.15 CAM42742.1 - 0.19 12.2 0.1 0.55 10.7 0.1 1.7 1 0 0 1 1 1 0 L71 family Peptidase_S80 PF07230.11 CAM42743.1 - 0.16 10.2 0.0 0.2 9.9 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage T4-like capsid assembly protein (Gp20) Aldo_ket_red PF00248.21 CAM42744.1 - 1.7e-56 191.6 0.0 3.5e-55 187.3 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Clathrin PF00637.20 CAM42745.1 - 2.1e-09 37.4 2.5 5.9e-08 32.7 0.5 2.8 2 0 0 2 2 2 1 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 CAM42745.1 - 0.018 15.0 12.7 0.049 13.7 12.7 1.8 1 0 0 1 1 1 0 Zinc-finger zf-ANAPC11 PF12861.7 CAM42745.1 - 0.1 12.7 2.6 0.31 11.1 2.6 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RNA_pol_Rpb1_1 PF04997.12 CAM42745.1 - 0.17 11.2 0.4 0.29 10.4 0.4 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 Vps39_2 PF10367.9 CAM42745.1 - 0.39 11.2 9.8 0.39 11.2 5.4 2.4 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-RING_UBOX PF13445.6 CAM42745.1 - 0.45 10.6 11.0 0.78 9.8 5.6 3.0 2 0 0 2 2 2 0 RING-type zinc-finger zf-rbx1 PF12678.7 CAM42745.1 - 0.6 10.4 8.0 1.9 8.9 8.0 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CAM42745.1 - 1.2 9.0 16.6 0.16 11.9 10.5 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CAM42745.1 - 4.2 7.4 16.6 1.4 8.9 11.3 2.5 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.6 CAM42745.1 - 4.9 7.6 13.3 2.3 8.6 9.9 2.4 2 0 0 2 2 2 0 Ring finger domain Nup54 PF13874.6 CAM42746.1 - 3.8e-21 75.7 0.4 3.8e-21 75.7 0.4 1.7 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nup54_C PF18437.1 CAM42746.1 - 0.011 15.6 0.9 0.011 15.6 0.9 2.1 2 0 0 2 2 2 0 Nup54 C-terminal interacting domain RIIa PF02197.17 CAM42747.1 - 0.074 12.7 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit DUF4588 PF15251.6 CAM42748.1 - 0.0034 17.2 0.1 0.0076 16.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4588) Inositol_P PF00459.25 CAM42749.1 - 1.9e-18 66.9 0.0 1.2e-17 64.4 0.0 2.2 1 1 0 1 1 1 1 Inositol monophosphatase family SQS_PSY PF00494.19 CAM42751.1 - 3.5e-46 157.8 0.1 5.2e-46 157.3 0.1 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase NUDIX PF00293.28 CAM42752.1 - 7.6e-16 58.3 0.0 1.6e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.11 CAM42752.1 - 1.2e-07 31.3 4.0 2.1e-07 30.4 4.0 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain DZR PF12773.7 CAM42752.1 - 0.0014 18.6 1.0 0.0028 17.7 1.0 1.4 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 CAM42752.1 - 0.015 15.3 1.0 0.15 12.1 0.4 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RecR PF02132.15 CAM42752.1 - 0.029 13.9 0.2 0.054 13.1 0.2 1.4 1 0 0 1 1 1 0 RecR protein NUDIX-like PF09296.11 CAM42752.1 - 0.077 13.7 0.0 0.15 12.7 0.0 1.5 1 0 0 1 1 1 0 NADH pyrophosphatase-like rudimentary NUDIX domain zinc_ribbon_2 PF13240.6 CAM42752.1 - 0.2 11.4 3.7 0.51 10.1 0.6 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 CAM42752.1 - 0.36 10.3 2.0 0.94 9.0 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain UPF0547 PF10571.9 CAM42752.1 - 2.1 8.5 5.3 26 5.0 1.4 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Pkinase PF00069.25 CAM42753.1 - 1.5e-62 211.4 0.0 2e-62 211.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM42753.1 - 3.7e-43 147.7 0.0 5.5e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM42753.1 - 5.1e-08 32.6 0.0 1.6e-06 27.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like PH PF00169.29 CAM42753.1 - 1.3e-05 25.7 0.0 3.6e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 PH domain Haspin_kinase PF12330.8 CAM42753.1 - 0.0066 15.4 0.0 0.009 15.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CAM42753.1 - 0.13 11.6 0.3 0.56 9.5 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Carboxyl_trans PF01039.22 CAM42754.1 - 9.7e-126 420.3 0.0 1.3e-125 419.9 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 CAM42754.1 - 2.9e-50 170.7 0.0 5.3e-50 169.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ACC_central PF08326.12 CAM42754.1 - 1.8e-48 165.4 0.0 4.4e-47 160.8 0.0 2.1 1 1 0 1 1 1 1 Acetyl-CoA carboxylase, central region Biotin_carb_N PF00289.22 CAM42754.1 - 1.1e-27 96.8 0.0 9.3e-27 93.8 0.0 2.3 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CAM42754.1 - 4.8e-21 74.9 0.0 3.8e-20 72.0 0.0 2.5 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CAM42754.1 - 2.4e-07 30.5 0.0 6e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 CAM42754.1 - 0.00013 21.5 0.0 0.00033 20.2 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CAM42754.1 - 0.0005 19.7 0.1 0.0019 17.8 0.1 1.8 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 CAM42754.1 - 0.0083 16.2 0.1 0.02 15.0 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 CAM42754.1 - 0.2 11.5 0.0 0.55 10.1 0.0 1.7 1 0 0 1 1 1 0 Biotin-lipoyl like SMK-1 PF04802.15 CAM42755.1 - 2.2e-08 34.2 0.0 3.4e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 3-PAP PF12578.8 CAM42755.1 - 0.063 13.0 0.1 0.2 11.4 0.1 1.8 1 0 0 1 1 1 0 Myotubularin-associated protein FAM184 PF15665.5 CAM42756.1 - 0.0032 17.3 6.9 0.0032 17.3 6.9 9.6 7 2 2 9 9 9 2 Family with sequence similarity 184, A and B XhlA PF10779.9 CAM42756.1 - 4.7 7.5 5.5 40 4.5 0.2 4.1 3 0 0 3 3 3 0 Haemolysin XhlA ASL_C PF08328.11 CAM42758.1 - 0.034 14.2 1.5 0.034 14.2 1.5 2.0 2 1 0 2 2 2 0 Adenylosuccinate lyase C-terminal Mei5 PF10376.9 CAM42758.1 - 0.086 12.7 3.0 0.15 11.9 3.0 1.4 1 0 0 1 1 1 0 Double-strand recombination repair protein Bacillus_HBL PF05791.11 CAM42758.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.7 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) PIN_8 PF18476.1 CAM42758.1 - 0.18 11.7 9.8 0.13 12.1 7.6 1.8 1 1 0 1 1 1 0 PIN like domain Hydantoinase_B PF02538.14 CAM42758.1 - 0.28 9.6 3.4 0.4 9.0 3.4 1.2 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase Syntaxin-6_N PF09177.11 CAM42758.1 - 0.3 11.7 4.8 0.28 11.8 1.2 2.6 1 1 2 3 3 3 0 Syntaxin 6, N-terminal BCAS2 PF05700.11 CAM42758.1 - 2 8.1 17.2 0.53 9.9 12.2 2.0 1 1 1 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) DUF883 PF05957.13 CAM42758.1 - 6.2 7.5 23.9 1.5 9.5 8.0 3.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) TetR_C_27 PF17935.1 CAM42758.1 - 6.4 6.9 10.4 0.4 10.8 3.1 2.6 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain RE_AccI PF09545.10 CAM42763.1 - 0.052 12.5 0.0 0.066 12.2 0.0 1.2 1 0 0 1 1 1 0 AccI restriction endonuclease IRK PF01007.20 CAM42763.1 - 0.056 13.3 0.7 0.089 12.6 0.7 1.2 1 0 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain Phg_2220_C PF09524.10 CAM42763.1 - 0.19 11.9 2.2 2.1 8.5 0.1 2.3 1 1 1 2 2 2 0 Conserved phage C-terminus (Phg_2220_C) Cyclase PF04199.13 CAM42764.1 - 2.5e-16 60.1 0.0 3.6e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase Zip PF02535.22 CAM42765.1 - 7e-27 94.5 3.3 8e-27 94.3 3.3 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter BTB_2 PF02214.22 CAM42766.1 - 0.00029 21.1 0.0 0.00094 19.5 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain SPRY PF00622.28 CAM42766.1 - 0.04 14.0 0.0 0.15 12.2 0.0 1.9 1 1 0 1 1 1 0 SPRY domain Peptidase_M16_M PF16187.5 CAM42767.1 - 3.9e-31 108.4 0.0 7.6e-28 97.6 0.0 2.7 3 0 0 3 3 3 2 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 CAM42767.1 - 0.0016 18.5 0.0 0.025 14.6 0.0 2.6 2 0 0 2 2 2 1 Peptidase M16 inactive domain Nop14 PF04147.12 CAM42767.1 - 0.028 12.7 0.7 0.045 12.0 0.7 1.3 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 CAM42767.1 - 0.25 11.2 3.4 0.52 10.2 3.4 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region FAM176 PF14851.6 CAM42767.1 - 0.36 10.5 2.5 0.74 9.5 2.5 1.5 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 CAM42767.1 - 0.62 8.3 3.1 0.93 7.7 3.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.22 CAM42768.1 - 1.5e-40 139.5 8.5 1.9e-40 139.1 8.5 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Zip PF02535.22 CAM42769.1 - 6.5e-41 140.6 8.1 8.6e-41 140.3 8.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Zip PF02535.22 CAM42770.1 - 1.1e-32 113.6 8.2 1.5e-32 113.2 8.2 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter BTB_2 PF02214.22 CAM42771.1 - 0.00029 21.1 0.0 0.00094 19.5 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain SPRY PF00622.28 CAM42771.1 - 0.041 14.0 0.0 0.15 12.2 0.0 1.9 1 1 0 1 1 1 0 SPRY domain Peptidase_M16 PF00675.20 CAM42772.1 - 1.8e-32 112.4 0.0 4e-32 111.3 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_M PF16187.5 CAM42772.1 - 1.2e-30 106.8 0.0 1.4e-27 96.7 0.0 2.6 3 0 0 3 3 3 2 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 CAM42772.1 - 2.1e-14 54.0 0.0 4.7e-09 36.5 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Nop14 PF04147.12 CAM42772.1 - 0.037 12.3 0.9 0.061 11.5 0.9 1.3 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 CAM42772.1 - 0.12 12.2 3.8 0.74 9.7 3.6 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region FAM176 PF14851.6 CAM42772.1 - 0.53 9.9 2.5 1.1 8.9 2.5 1.4 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 CAM42772.1 - 1.1 7.5 3.7 1.7 6.8 3.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DnaJ PF00226.31 CAM42773.1 - 1.2e-16 60.5 0.0 2e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Autophagy_act_C PF03987.15 CAM42774.1 - 0.018 15.6 0.1 0.042 14.4 0.1 1.7 1 1 0 1 1 1 0 Autophagocytosis associated protein, active-site domain PEMT PF04191.13 CAM42776.2 - 1.4e-53 179.8 10.2 6.4e-30 103.7 0.8 2.9 2 0 0 2 2 2 2 Phospholipid methyltransferase Phage_NinH PF06322.11 CAM42776.2 - 0.13 12.2 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Phage NinH protein CPSase_L_D2 PF02786.17 CAM42777.2 - 1e-61 208.1 0.0 1.9e-61 207.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CAM42777.2 - 1.1e-43 148.2 0.1 3e-43 146.8 0.0 1.8 2 0 0 2 2 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CAM42777.2 - 3.7e-34 117.1 0.0 7.3e-34 116.1 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CAM42777.2 - 5.9e-14 51.7 0.3 1.2e-13 50.7 0.3 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 CAM42777.2 - 4.9e-11 42.6 0.0 1.2e-10 41.3 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CAM42777.2 - 4.9e-10 39.2 0.1 8.2e-10 38.5 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 CAM42777.2 - 1.9e-05 24.4 0.1 0.00031 20.5 0.0 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like ATP-grasp_3 PF02655.14 CAM42777.2 - 0.0016 18.5 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 CAM42777.2 - 0.046 13.3 0.0 0.44 10.1 0.0 2.1 1 1 0 1 1 1 0 RimK-like ATP-grasp domain HlyD_3 PF13437.6 CAM42777.2 - 0.13 13.0 0.1 15 6.3 0.0 2.9 3 0 0 3 3 3 0 HlyD family secretion protein DUF3983 PF13137.6 CAM42777.2 - 0.16 11.8 0.0 0.4 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3983) Robl_LC7 PF03259.17 CAM42779.1 - 0.00015 21.4 0.0 0.00086 19.0 0.0 1.9 1 1 0 1 1 1 1 Roadblock/LC7 domain Thioredoxin PF00085.20 CAM42780.2 - 0.024 14.6 1.4 0.058 13.4 1.4 1.6 1 0 0 1 1 1 0 Thioredoxin PQQ_3 PF13570.6 CAM42780.2 - 0.094 13.2 7.6 18 5.9 0.0 5.1 5 0 0 5 5 5 0 PQQ-like domain SHE3 PF17078.5 CAM42780.2 - 0.31 10.7 10.1 1.1 8.9 1.2 2.3 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 Peptidase_C6 PF00851.18 CAM42780.2 - 0.34 9.8 4.9 0.73 8.7 0.5 2.4 2 0 0 2 2 2 0 Helper component proteinase UPF0184 PF03670.13 CAM42780.2 - 0.54 10.7 2.8 1.9 9.0 2.8 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Pkinase PF00069.25 CAM42781.1 - 5.7e-61 206.2 0.0 7.7e-61 205.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM42781.1 - 1.9e-41 142.1 0.0 2.6e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 CAM42781.1 - 4.9e-13 49.5 0.0 9.8e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 CAM42781.1 - 4.5e-08 32.8 0.0 7.3e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH_9 PF15410.6 CAM42781.1 - 5.3e-08 33.2 0.2 1.4e-06 28.6 0.2 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain Pkinase_fungal PF17667.1 CAM42781.1 - 0.0022 16.8 0.2 0.059 12.1 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase MFS_1 PF07690.16 CAM42782.1 - 8.1e-18 64.5 22.4 8.1e-18 64.5 22.4 2.4 1 1 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 CAM42782.1 - 3.4e-07 30.0 23.3 3.4e-07 30.0 23.3 3.2 2 2 1 3 3 3 1 Nodulin-like DUF3093 PF11292.8 CAM42782.1 - 0.022 15.0 1.0 0.022 15.0 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) TssO PF17561.2 CAM42782.1 - 0.14 12.2 4.7 0.17 12.0 0.0 3.1 3 0 0 3 3 3 0 Type VI secretion system, TssO CENP-T_C PF15511.6 CAM42783.1 - 1e-05 25.6 0.1 1.7e-05 24.9 0.0 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CAM42783.1 - 0.00056 20.0 0.1 0.00088 19.4 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 CAM42783.1 - 0.00058 20.1 0.4 0.00081 19.6 0.0 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 CAM42783.1 - 0.0025 17.8 0.0 0.0029 17.6 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 CAM42783.1 - 0.0042 17.4 1.7 0.0082 16.5 1.7 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CAM42783.1 - 0.063 13.3 0.0 0.083 13.0 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit NopRA1 PF16201.5 CAM42785.2 - 0.12 12.0 0.2 0.21 11.1 0.2 1.3 1 0 0 1 1 1 0 Nucleolar pre-ribosomal-associated protein 1 CysA_C_terminal PF17850.1 CAM42786.1 - 0.26 11.9 1.1 0.94 10.1 0.3 2.1 2 0 0 2 2 2 0 CysA C-terminal regulatory domain Pho88 PF10032.9 CAM42789.1 - 3.6e-21 75.2 0.0 4.8e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Phosphate transport (Pho88) LRR_8 PF13855.6 CAM42790.1 - 5.6e-05 22.8 0.4 0.0043 16.8 0.5 2.6 1 1 2 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 CAM42790.1 - 0.00032 21.0 0.2 3 8.4 0.0 3.3 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 CAM42790.1 - 0.059 13.7 0.1 0.059 13.7 0.1 2.9 5 0 0 5 5 5 0 Leucine rich repeat N-terminal domain SOG2 PF10428.9 CAM42790.1 - 1.9 7.6 14.0 2.8 7.1 14.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein CorA PF01544.18 CAM42791.1 - 4.6e-08 32.7 0.4 2e-05 24.0 0.2 2.1 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein CSD PF00313.22 CAM42793.1 - 0.00071 19.4 0.0 2 8.3 0.0 3.1 3 0 0 3 3 3 2 'Cold-shock' DNA-binding domain RINGv PF12906.7 CAM42793.1 - 0.19 11.9 0.0 0.36 11.0 0.0 1.4 1 0 0 1 1 1 0 RING-variant domain Phage_integrase PF00589.22 CAM42796.1 - 7.2e-07 29.2 0.0 4.1e-06 26.7 0.0 2.3 2 0 0 2 2 2 1 Phage integrase family RVT_1 PF00078.27 CAM42796.1 - 0.0033 17.0 0.0 0.009 15.6 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A17 PF05380.13 CAM42796.1 - 0.0039 17.2 0.1 0.043 13.8 0.0 2.3 1 1 1 2 2 2 1 Pao retrotransposon peptidase RasGEF_N_2 PF14663.6 CAM42798.1 - 0.089 13.2 1.9 0.23 11.9 0.3 2.3 1 1 1 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain GIT_CC PF16559.5 CAM42798.1 - 0.21 11.5 2.6 6.9 6.6 0.0 3.6 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Sec34 PF04136.15 CAM42798.1 - 0.52 10.2 9.8 14 5.6 3.0 3.7 3 1 0 4 4 4 0 Sec34-like family DUF948 PF06103.11 CAM42798.1 - 0.62 10.4 2.5 7.3 6.9 0.2 3.5 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Myotub-related PF06602.14 CAM42798.1 - 0.84 8.5 7.8 0.22 10.4 0.9 2.1 1 1 0 2 2 2 0 Myotubularin-like phosphatase domain TrbM PF07424.11 CAM42798.1 - 1.2 9.0 5.0 0.91 9.5 0.6 2.5 1 1 2 3 3 3 0 TrbM DUF4407 PF14362.6 CAM42798.1 - 6.1 6.1 37.9 2.1 7.7 17.0 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) RVT_1 PF00078.27 CAM42799.1 - 0.00065 19.3 0.0 0.0022 17.6 0.0 1.8 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A17 PF05380.13 CAM42799.1 - 0.0008 19.4 0.1 0.025 14.6 0.0 2.3 1 1 1 2 2 2 1 Pao retrotransposon peptidase Phage_integrase PF00589.22 CAM42799.1 - 0.009 15.8 0.1 0.058 13.2 0.0 2.2 2 0 0 2 2 2 1 Phage integrase family RasGEF_N_2 PF14663.6 CAM42801.1 - 0.087 13.2 1.9 0.23 11.9 0.3 2.3 1 1 1 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain GIT_CC PF16559.5 CAM42801.1 - 0.21 11.5 2.6 6.9 6.6 0.0 3.6 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF948 PF06103.11 CAM42801.1 - 0.61 10.4 2.5 7.3 6.9 0.2 3.5 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Myotub-related PF06602.14 CAM42801.1 - 0.83 8.5 7.8 0.22 10.4 0.9 2.1 1 1 0 2 2 2 0 Myotubularin-like phosphatase domain TrbM PF07424.11 CAM42801.1 - 1.2 9.1 5.0 0.91 9.5 0.6 2.5 1 1 2 3 3 3 0 TrbM DUF4407 PF14362.6 CAM42801.1 - 6 6.1 37.9 2.1 7.7 17.0 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Sec34 PF04136.15 CAM42801.1 - 7.1 6.5 13.8 14 5.6 3.0 3.8 4 1 0 5 5 5 0 Sec34-like family zf-CCCH PF00642.24 CAM42802.1 - 0.0087 16.0 0.3 0.0087 16.0 0.3 2.1 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CAM42802.1 - 0.02 15.0 0.7 0.041 14.0 0.7 1.6 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH PF00642.24 CAM42804.2 - 0.011 15.6 0.7 0.011 15.6 0.7 1.9 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) WD40 PF00400.32 CAM42805.1 - 1.3e-17 63.9 4.3 0.025 15.4 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM42805.1 - 2.9e-05 24.3 0.2 0.58 10.5 0.0 3.6 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain NifU_N PF01592.16 CAM42805.1 - 0.19 11.9 0.0 1.2 9.3 0.0 2.2 3 0 0 3 3 3 0 NifU-like N terminal domain SNARE PF05739.19 CAM42807.1 - 7.5e-10 38.7 1.3 9.5e-09 35.1 0.0 2.7 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.25 CAM42807.1 - 0.0002 21.1 12.2 0.00063 19.5 7.2 2.5 2 1 0 2 2 2 1 Syntaxin DUF2935 PF11155.8 CAM42807.1 - 0.024 15.0 0.0 1.2 9.5 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) Baculo_PEP_C PF04513.12 CAM42807.1 - 0.048 13.7 5.3 4 7.5 0.2 3.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SF-assemblin PF06705.11 CAM42807.1 - 0.067 12.5 4.2 1.3 8.3 0.8 2.3 1 1 1 2 2 2 0 SF-assemblin/beta giardin DUF4208 PF13907.6 CAM42807.1 - 0.11 12.9 1.3 4.2 7.9 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) DUF16 PF01519.16 CAM42807.1 - 0.79 10.2 8.5 0.36 11.3 0.8 2.9 2 2 1 3 3 3 0 Protein of unknown function DUF16 Sec8_exocyst PF04048.14 CAM42807.1 - 1.6 8.6 7.5 0.65 9.9 0.3 3.0 2 1 0 3 3 3 0 Sec8 exocyst complex component specific domain DUF883 PF05957.13 CAM42807.1 - 6.1 7.5 7.9 0.85 10.3 0.9 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) NMT PF01233.19 CAM42808.1 - 1.5e-66 223.2 0.0 2.8e-66 222.3 0.0 1.5 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 CAM42808.1 - 2e-63 213.7 0.0 3.2e-63 213.1 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain TMEM239 PF15841.5 CAM42809.2 - 0.023 14.6 0.4 0.039 13.8 0.4 1.4 1 0 0 1 1 1 0 Transmembrane protein 239 family NIF PF03031.18 CAM42811.1 - 2.8e-26 92.1 0.0 3.5e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Mito_carr PF00153.27 CAM42812.1 - 2.7e-40 136.2 5.2 1.2e-14 54.0 0.0 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CAM42812.1 - 0.1 11.7 1.3 9.7 5.3 0.1 2.6 2 1 1 3 3 3 0 Gammaproteobacterial serine protease Pkinase PF00069.25 CAM42813.1 - 6e-58 196.3 0.0 7.7e-58 195.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM42813.1 - 4.5e-27 95.0 0.0 6.4e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAM42813.1 - 9.4e-05 21.4 0.0 0.00015 20.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CAM42813.1 - 0.00035 20.0 0.0 0.00058 19.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CAM42813.1 - 0.0015 17.9 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CAM42813.1 - 0.022 13.7 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 CAM42813.1 - 0.17 11.5 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CAM42813.1 - 0.2 11.6 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3080 PF11279.8 CAM42814.1 - 0.098 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) Arm PF00514.23 CAM42815.2 - 2.4e-40 135.4 24.7 7.7e-08 32.1 0.1 16.7 16 2 1 17 17 17 9 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 CAM42815.2 - 1.4e-09 37.9 0.4 0.024 14.1 0.0 5.5 4 2 1 6 6 6 2 Armadillo-like Atx10homo_assoc PF09759.9 CAM42815.2 - 9e-05 22.4 1.2 1.9 8.6 0.0 6.2 7 0 0 7 7 7 1 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.22 CAM42815.2 - 0.045 14.0 5.7 23 5.6 0.3 5.9 5 1 0 5 5 5 0 HEAT repeat WAPL PF07814.13 CAM42815.2 - 0.92 8.2 7.1 2.3 6.9 1.3 4.1 2 1 1 3 3 3 0 Wings apart-like protein regulation of heterochromatin Utp14 PF04615.13 CAM42816.2 - 6.6e-111 372.2 31.1 6.6e-111 372.2 31.1 1.9 1 1 1 2 2 2 1 Utp14 protein LRR_9 PF14580.6 CAM42819.1 - 5.1e-20 71.7 0.8 1.2e-19 70.4 0.8 1.6 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CAM42819.1 - 0.074 13.5 0.5 15 6.2 0.0 3.3 2 2 1 3 3 3 0 Leucine Rich repeats (2 copies) CCDC-167 PF15188.6 CAM42819.1 - 0.18 12.2 5.1 0.24 11.8 2.4 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 HSP70 PF00012.20 CAM42821.1 - 2.6e-05 22.6 0.1 0.0039 15.5 0.0 2.4 2 0 0 2 2 2 2 Hsp70 protein Filament PF00038.21 CAM42822.2 - 0.032 13.8 15.1 0.59 9.7 15.0 2.7 1 1 0 1 1 1 0 Intermediate filament protein Fib_alpha PF08702.10 CAM42822.2 - 0.14 12.3 9.2 0.17 12.1 0.3 3.7 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 CAM42822.2 - 7 7.2 8.2 7.7 7.1 0.1 3.9 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Rtt106 PF08512.12 CAM42823.2 - 6.5e-12 45.7 0.0 1.6e-10 41.2 0.0 2.7 3 0 0 3 3 3 1 Histone chaperone Rttp106-like SSrecog PF03531.14 CAM42823.2 - 3.7e-05 23.5 0.0 0.00023 21.0 0.0 2.4 2 1 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Nop53 PF07767.11 CAM42823.2 - 0.0051 16.3 29.5 0.0079 15.6 29.5 1.3 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) YL1 PF05764.13 CAM42823.2 - 0.0056 16.8 39.2 0.0076 16.4 39.2 1.1 1 0 0 1 1 1 1 YL1 nuclear protein Coilin_N PF15862.5 CAM42823.2 - 0.023 14.5 18.5 0.96 9.2 18.5 2.3 1 1 0 1 1 1 0 Coilin N-terminus EOS1 PF12326.8 CAM42823.2 - 0.17 11.8 3.3 0.31 11.0 3.3 1.4 1 0 0 1 1 1 0 N-glycosylation protein Nop14 PF04147.12 CAM42823.2 - 0.19 9.9 34.9 0.24 9.5 34.9 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 CAM42823.2 - 0.2 11.0 39.3 0.26 10.7 39.3 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 CAM42823.2 - 1.3 7.3 37.4 1.8 6.8 37.4 1.1 1 0 0 1 1 1 0 CDC45-like protein RNA_polI_A34 PF08208.11 CAM42823.2 - 3.2 7.8 38.6 6.7 6.7 38.6 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Neur_chan_memb PF02932.16 CAM42823.2 - 6.4 6.8 6.5 8.6 6.3 6.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Apt1 PF10351.9 CAM42823.2 - 6.9 5.4 20.6 9.1 5.0 20.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain BTV_NS2 PF04514.12 CAM42823.2 - 7.6 5.3 15.4 12 4.6 15.4 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Adhesin_P1 PF03257.13 CAM42824.1 - 0.026 15.0 1.3 0.026 15.0 1.3 2.7 2 0 0 2 2 2 0 Mycoplasma adhesin P1 MPM1 PF17234.2 CAM42824.1 - 0.22 11.7 2.5 0.73 10.1 2.5 1.8 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 OmpH PF03938.14 CAM42824.1 - 9.2 6.6 7.5 1.6 9.1 2.6 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Dynein_light PF01221.18 CAM42825.1 - 6.5e-41 138.6 0.9 7.2e-41 138.4 0.9 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Peptidase_C3 PF00548.20 CAM42825.1 - 0.017 15.0 0.0 0.018 15.0 0.0 1.1 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) Imm48 PF15574.6 CAM42825.1 - 0.063 13.1 0.1 0.084 12.7 0.1 1.1 1 0 0 1 1 1 0 Immunity protein 48 Ectatomin PF06457.11 CAM42825.1 - 0.065 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Ectatomin LRR_4 PF12799.7 CAM42826.1 - 0.0031 17.9 3.1 2.3 8.8 0.1 3.9 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) AATF-Che1 PF13339.6 CAM42826.1 - 0.14 12.8 2.2 0.4 11.4 0.9 2.3 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor AAA_13 PF13166.6 CAM42826.1 - 0.21 10.2 1.9 0.31 9.6 1.9 1.2 1 0 0 1 1 1 0 AAA domain LRR_8 PF13855.6 CAM42826.1 - 0.23 11.2 1.9 8 6.3 0.1 3.4 3 0 0 3 3 3 0 Leucine rich repeat LRR_6 PF13516.6 CAM42826.1 - 0.24 11.5 1.5 43 4.5 0.1 4.1 4 0 0 4 4 4 0 Leucine Rich repeat Atg14 PF10186.9 CAM42826.1 - 1.5 7.8 11.7 3.1 6.8 11.7 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4200 PF13863.6 CAM42826.1 - 2.1 8.7 15.1 6.5 7.2 1.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Spectrin PF00435.21 CAM42826.1 - 3.1 8.3 10.7 2.4 8.7 3.5 2.7 1 1 1 2 2 2 0 Spectrin repeat Pkinase PF00069.25 CAM42828.1 - 3.2e-67 226.7 0.0 5.1e-67 226.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM42828.1 - 1.3e-51 175.4 0.1 2.1e-51 174.7 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM42828.1 - 2.4e-05 23.8 0.3 6.4e-05 22.4 0.0 1.8 3 0 0 3 3 3 1 Kinase-like RIO1 PF01163.22 CAM42828.1 - 0.01 15.5 0.2 0.03 13.9 0.2 1.7 1 0 0 1 1 1 0 RIO1 family LRR_8 PF13855.6 CAM42832.1 - 6.4e-11 41.9 13.2 3.2e-06 26.8 1.9 5.3 4 1 1 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 CAM42832.1 - 4.3e-10 39.7 5.9 0.013 15.9 0.2 4.2 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CAM42832.1 - 0.00087 18.8 0.5 0.19 11.2 0.0 2.7 2 1 1 3 3 3 1 Leucine-rich repeat LRR_1 PF00560.33 CAM42832.1 - 0.0039 17.5 5.8 21 6.2 0.1 5.4 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 CAM42832.1 - 0.029 14.4 14.0 1.2 9.4 1.1 5.9 7 0 0 7 7 7 0 Leucine Rich repeat TPR_19 PF14559.6 CAM42833.2 - 3.2e-10 40.4 13.1 0.018 15.5 0.5 8.3 7 1 1 8 8 7 2 Tetratricopeptide repeat Clathrin PF00637.20 CAM42833.2 - 1.1e-06 28.5 0.4 1.1 9.1 0.0 5.2 5 2 1 6 6 6 1 Region in Clathrin and VPS Coatomer_WDAD PF04053.14 CAM42833.2 - 1.4e-05 24.4 0.5 0.032 13.3 0.0 3.3 2 1 1 3 3 3 2 Coatomer WD associated region TPR_14 PF13428.6 CAM42833.2 - 0.0002 21.9 27.6 2.8 9.0 2.3 10.1 8 2 1 9 9 9 2 Tetratricopeptide repeat Nic96 PF04097.14 CAM42833.2 - 0.00022 19.8 3.3 0.82 8.0 0.0 4.0 2 1 1 3 3 3 2 Nup93/Nic96 TPR_7 PF13176.6 CAM42833.2 - 0.00039 20.2 20.0 0.37 10.9 0.6 6.9 8 0 0 8 8 7 3 Tetratricopeptide repeat ANAPC4_WD40 PF12894.7 CAM42833.2 - 0.00099 19.4 0.0 0.26 11.6 0.0 3.7 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CAM42833.2 - 0.011 16.6 0.1 8.5 7.4 0.0 3.4 2 0 0 2 2 2 0 WD domain, G-beta repeat Nucleoporin_N PF08801.11 CAM42833.2 - 0.017 13.9 0.0 0.034 12.9 0.0 1.4 1 0 0 1 1 1 0 Nup133 N terminal like TPR_1 PF00515.28 CAM42833.2 - 0.073 12.9 16.9 8.3 6.4 0.2 7.1 6 1 0 6 6 6 0 Tetratricopeptide repeat PPR PF01535.20 CAM42833.2 - 0.15 12.4 0.9 1.5e+02 3.0 0.1 5.2 4 1 0 4 4 4 0 PPR repeat TPR_2 PF07719.17 CAM42833.2 - 0.44 10.8 29.9 4 7.8 1.6 9.2 9 1 0 9 9 9 0 Tetratricopeptide repeat TPR_16 PF13432.6 CAM42833.2 - 3.5 8.4 27.2 0.078 13.6 2.6 6.5 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 CAM42833.2 - 4 7.9 14.1 55 4.4 0.2 7.0 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 CAM42833.2 - 6.2 7.2 25.9 14 6.0 0.4 7.7 9 1 0 9 9 7 0 Tetratricopeptide repeat MIT PF04212.18 CAM42833.2 - 9.8 6.3 16.2 17 5.6 0.1 6.0 7 1 0 7 7 7 0 MIT (microtubule interacting and transport) domain DUF3774 PF12609.8 CAM42837.2 - 1.4 10.0 11.8 0.31 12.1 4.3 3.5 2 1 0 2 2 2 0 Wound-induced protein RHD3 PF05879.12 CAM42839.2 - 1.6e-106 357.2 0.0 1.5e-93 314.4 0.0 3.3 1 1 1 3 3 3 3 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.23 CAM42839.2 - 3.1e-05 24.1 0.0 6.3e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.6 CAM42839.2 - 0.0048 17.2 2.5 0.0085 16.3 0.1 2.6 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 CAM42839.2 - 0.015 15.4 0.0 0.035 14.2 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase JAB PF01398.21 CAM42841.1 - 3.5e-25 88.3 0.0 6.3e-24 84.2 0.0 2.2 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 CAM42841.1 - 4.4e-18 65.7 0.9 8.7e-18 64.8 0.4 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function ASL_C PF08328.11 CAM42841.1 - 0.03 14.4 0.7 3.5 7.8 0.2 2.4 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminal DEAD PF00270.29 CAM42842.1 - 1.2e-46 158.7 0.0 2e-46 158.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAM42842.1 - 1.2e-32 112.5 0.0 3.9e-31 107.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 CAM42842.1 - 0.0021 17.3 0.0 0.0031 16.7 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 CAM42842.1 - 0.049 13.9 0.0 0.41 10.9 0.0 2.2 1 1 0 1 1 1 0 AAA domain TPR_2 PF07719.17 CAM42843.1 - 0.00039 20.3 26.3 1.1 9.6 0.0 8.9 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 CAM42843.1 - 0.06 13.9 23.0 0.82 10.2 1.7 5.3 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 CAM42843.1 - 0.13 12.1 7.4 4.6 7.2 1.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat HemY_N PF07219.13 CAM42843.1 - 0.22 11.7 4.7 48 4.2 0.1 4.1 3 0 0 3 3 3 0 HemY protein N-terminus TPR_12 PF13424.6 CAM42843.1 - 1.2 9.5 27.6 1.9 8.8 0.1 6.8 6 1 0 7 7 7 0 Tetratricopeptide repeat Kinesin PF00225.23 CAM42844.1 - 4.6e-32 111.2 0.0 6.3e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain MORN PF02493.20 CAM42844.1 - 8.8e-14 50.5 36.3 0.00027 20.6 0.0 7.4 7 0 0 7 7 7 5 MORN repeat Microtub_bd PF16796.5 CAM42844.1 - 3.9e-10 39.9 0.0 6.6e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding Ribosomal_L22 PF00237.19 CAM42845.1 - 1.1e-31 109.1 0.3 1.4e-31 108.8 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF1279 PF06916.13 CAM42846.1 - 1.1e-06 29.1 0.1 1.6e-06 28.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) WW PF00397.26 CAM42846.1 - 3.9e-05 23.6 0.8 7.7e-05 22.7 0.8 1.5 1 0 0 1 1 1 1 WW domain Ribosomal_S5_C PF03719.15 CAM42847.1 - 4.8e-25 86.8 0.0 7.9e-25 86.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 CAM42847.1 - 6.5e-23 80.5 0.8 1.3e-22 79.5 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain FoP_duplication PF13865.6 CAM42847.1 - 0.15 12.6 8.2 0.34 11.5 8.2 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Phage_tail_NK PF16532.5 CAM42847.1 - 0.21 11.2 0.0 0.34 10.5 0.0 1.2 1 0 0 1 1 1 0 Sf6-type phage tail needle knob or tip of some Caudovirales Aldo_ket_red PF00248.21 CAM42848.1 - 3.1e-57 194.0 0.0 2.4e-55 187.8 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family LRR_6 PF13516.6 CAM42849.1 - 0.00013 21.7 22.1 2.2 8.5 0.0 9.5 11 0 0 11 11 11 2 Leucine Rich repeat LRR_4 PF12799.7 CAM42849.1 - 0.02 15.3 9.4 2 8.9 0.0 6.4 7 1 0 7 7 7 0 Leucine Rich repeats (2 copies) RR_TM4-6 PF06459.12 CAM42849.1 - 0.47 10.2 7.5 0.83 9.4 7.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 CAM42849.1 - 1.2 7.3 16.4 2.3 6.4 16.4 1.4 1 0 0 1 1 1 0 CDC45-like protein CLN3 PF02487.17 CAM42849.1 - 1.6 7.7 3.8 6.7 5.7 0.0 2.4 3 0 0 3 3 3 0 CLN3 protein SDA1 PF05285.12 CAM42849.1 - 2.3 7.6 21.2 4.4 6.6 21.2 1.4 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 CAM42849.1 - 9 4.4 20.7 13 3.8 20.7 1.2 1 0 0 1 1 1 0 Nop14-like family TauE PF01925.19 CAM42850.1 - 2.2e-20 73.3 24.4 9.1e-14 51.7 1.2 2.5 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE OTT_1508_deam PF14441.6 CAM42851.1 - 0.12 12.4 0.2 0.2 11.7 0.2 1.3 1 0 0 1 1 1 0 OTT_1508-like deaminase Profilin PF00235.19 CAM42852.1 - 6.2e-42 142.9 0.4 7.9e-42 142.5 0.4 1.1 1 0 0 1 1 1 1 Profilin CDC50 PF03381.15 CAM42853.1 - 2.4e-47 161.8 0.0 2.9e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF1708 PF08101.11 CAM42854.1 - 0.0081 15.4 0.1 0.019 14.1 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1708) Ras PF00071.22 CAM42855.1 - 2.3e-55 186.6 0.1 2.7e-55 186.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAM42855.1 - 6.7e-35 119.9 0.1 1.1e-34 119.3 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAM42855.1 - 4.3e-14 52.3 0.0 5.1e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CAM42855.1 - 3.4e-06 26.7 0.2 4.5e-05 23.1 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CAM42855.1 - 2.2e-05 24.5 0.0 5e-05 23.4 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CAM42855.1 - 0.00036 19.9 0.0 0.00045 19.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Septin PF00735.18 CAM42855.1 - 0.00062 19.1 0.0 0.00094 18.5 0.0 1.2 1 0 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 CAM42855.1 - 0.00097 19.1 0.0 0.035 14.0 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase NACHT PF05729.12 CAM42855.1 - 0.0098 15.8 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 NACHT domain PduV-EutP PF10662.9 CAM42855.1 - 0.014 15.1 0.2 0.061 13.1 0.1 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 CAM42855.1 - 0.029 14.7 0.0 0.057 13.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CAM42855.1 - 0.036 14.5 0.0 0.11 12.9 0.0 2.0 1 1 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 CAM42855.1 - 0.041 14.3 0.0 0.05 14.0 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 CAM42855.1 - 0.11 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein AAA_7 PF12775.7 CAM42855.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 CAM42855.1 - 0.13 11.9 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain YwhD PF08741.10 CAM42855.1 - 0.13 11.9 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 YwhD family Med11 PF10280.9 CAM42856.1 - 0.049 14.1 0.4 0.09 13.2 0.4 1.4 1 0 0 1 1 1 0 Mediator complex protein Rtf2 PF04641.12 CAM42857.1 - 8.1e-25 87.7 0.5 1.4e-24 86.9 0.5 1.4 1 1 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 CAM42857.1 - 0.014 15.2 0.0 0.38 10.6 0.0 2.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 CAM42857.1 - 0.041 14.0 0.0 0.093 12.9 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Prok-RING_4 PF14447.6 CAM42857.1 - 0.056 13.3 0.9 0.14 12.1 0.9 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Mss51 PF13824.6 CAM42857.1 - 0.061 13.4 0.9 0.63 10.2 0.4 2.4 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 MTCP1 PF08991.10 CAM42858.1 - 0.0039 17.4 2.8 0.0039 17.4 2.8 2.2 2 1 0 2 2 2 1 Mature-T-Cell Proliferation I type XG_FTase PF03254.13 CAM42858.1 - 0.065 11.8 0.3 0.28 9.7 0.1 1.8 2 0 0 2 2 2 0 Xyloglucan fucosyltransferase Cmc1 PF08583.10 CAM42858.1 - 0.18 11.9 11.4 0.7 10.0 0.2 3.3 2 2 1 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 CAM42858.1 - 0.25 11.7 5.7 0.48 10.8 0.4 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 UPF0203 PF05254.12 CAM42858.1 - 0.98 9.7 10.7 6.6 7.1 0.0 3.1 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0203) CHCH PF06747.13 CAM42858.1 - 3.7 7.8 15.7 0.81 9.9 0.8 2.7 3 0 0 3 3 3 0 CHCH domain zf-C3HC4_3 PF13920.6 CAM42859.1 - 2e-05 24.4 17.7 3.4e-05 23.6 17.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 CAM42860.1 - 4.8e-33 114.4 0.1 1e-32 113.3 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAM42860.1 - 2.6e-27 95.4 0.0 1.5e-26 92.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAM42860.1 - 2.5e-05 24.3 0.1 7.4e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit YL1 PF05764.13 CAM42861.1 - 0.00052 20.2 8.3 0.00052 20.2 8.3 1.8 2 0 0 2 2 2 1 YL1 nuclear protein SPT6_acidic PF14632.6 CAM42861.1 - 0.35 11.5 14.5 7.8 7.2 13.8 2.7 2 0 0 2 2 2 0 Acidic N-terminal SPT6 LRR19-TM PF15176.6 CAM42861.1 - 0.36 10.8 2.4 0.89 9.6 2.4 1.7 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Spt5_N PF11942.8 CAM42861.1 - 1.2 10.2 19.3 0.16 13.0 14.0 2.1 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal CDC45 PF02724.14 CAM42861.1 - 5.7 5.1 11.2 9.1 4.4 11.2 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 CAM42861.1 - 9.5 5.4 11.0 19 4.5 11.0 1.4 1 0 0 1 1 1 0 NOA36 protein DnaJ PF00226.31 CAM42862.1 - 2.1e-09 37.4 0.0 5.7e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain TMCO5 PF14992.6 CAM42862.1 - 8.3 5.9 9.7 7.3 6.1 1.3 2.8 1 1 0 2 2 2 0 TMCO5 family WD40 PF00400.32 CAM42864.1 - 2.2e-10 41.0 1.9 0.00074 20.3 0.1 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CAM42864.1 - 0.0051 15.8 0.1 19 4.1 0.0 3.5 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein MFS18 PF17352.2 CAM42864.1 - 0.03 14.7 1.5 0.067 13.6 1.5 1.5 1 0 0 1 1 1 0 Male Flower Specific protein 18 ANAPC4_WD40 PF12894.7 CAM42864.1 - 0.096 13.0 0.1 15 6.0 0.0 3.4 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain MMS1_N PF10433.9 CAM42864.1 - 0.1 11.2 0.0 0.86 8.2 0.0 2.0 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term AMMECR1 PF01871.17 CAM42866.1 - 3.7e-47 160.0 0.0 4.3e-47 159.8 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 GP68 PF17469.2 CAM42866.1 - 0.15 12.5 0.0 4.5 7.7 0.0 2.2 2 0 0 2 2 2 0 Phage protein Gp68 DSPc PF00782.20 CAM42867.1 - 1.3e-12 47.7 0.0 2.7e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CAM42867.1 - 6.4e-11 42.3 0.0 1.5e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 CAM42867.1 - 8.2e-06 25.6 0.1 1.8e-05 24.5 0.0 1.6 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 CAM42867.1 - 0.00021 21.5 0.0 0.00041 20.5 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate RhoGAP PF00620.27 CAM42867.1 - 0.0036 17.1 0.0 0.0066 16.3 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Y_phosphatase3 PF13350.6 CAM42867.1 - 0.01 15.8 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family AKAP7_NLS PF10469.9 CAM42868.1 - 4.7e-41 141.0 0.0 5.7e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 CAM42868.1 - 1.5e-07 31.4 0.0 2.1e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily EF-hand_7 PF13499.6 CAM42869.1 - 4.2e-11 43.1 0.3 0.00064 20.1 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CAM42869.1 - 5.6e-10 38.3 0.8 0.0015 18.3 0.1 3.7 3 1 1 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 CAM42869.1 - 4.1e-08 32.2 0.4 0.0066 15.9 0.2 4.0 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 CAM42869.1 - 2.6e-06 27.2 6.7 0.00033 20.4 0.6 4.1 2 1 3 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.6 CAM42869.1 - 0.0094 15.4 1.2 0.67 9.6 0.1 3.0 3 0 0 3 3 3 1 EF hand YdiH PF15930.5 CAM42869.1 - 0.074 13.2 0.0 2.6 8.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function Kinesin PF00225.23 CAM42871.1 - 9.6e-99 330.4 0.1 9.6e-99 330.4 0.1 3.0 4 0 0 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 CAM42871.1 - 1.3e-25 90.1 4.8 1.8e-25 89.7 0.0 3.3 3 0 0 3 3 3 1 Microtubule binding DUF3800 PF12686.7 CAM42871.1 - 0.22 12.2 0.5 42 4.8 0.5 4.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) Exo_endo_phos_2 PF14529.6 CAM42871.1 - 1.5 8.7 4.3 2.9 7.8 1.4 2.7 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase DUF2244 PF10003.9 CAM42871.1 - 2.7 7.7 7.2 0.16 11.6 0.8 2.3 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) AAA_16 PF13191.6 CAM42871.1 - 3.5 8.0 0.0 3.5 8.0 0.0 4.5 5 1 0 5 5 5 0 AAA ATPase domain S4 PF01479.25 CAM42872.2 - 0.0052 16.5 0.0 0.0087 15.8 0.0 1.4 1 1 0 1 1 1 1 S4 domain UQ_con PF00179.26 CAM42873.1 - 8.8e-35 119.4 0.0 1.4e-34 118.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme BRE PF06113.12 CAM42873.1 - 0.087 11.7 0.0 1.7 7.4 0.0 2.1 1 1 1 2 2 2 0 Brain and reproductive organ-expressed protein (BRE) Mut7-C PF01927.16 CAM42874.1 - 3e-45 153.9 0.8 4.7e-45 153.3 0.8 1.2 1 0 0 1 1 1 1 Mut7-C RNAse domain LSM PF01423.22 CAM42875.1 - 1.7e-12 46.8 0.1 2.2e-12 46.5 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CAM42875.1 - 0.027 14.6 0.1 0.053 13.7 0.1 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain Pan3_PK PF18101.1 CAM42876.1 - 6.6e-40 136.3 0.6 9.6e-40 135.8 0.6 1.2 1 0 0 1 1 1 1 Pan3 Pseudokinase domain LRR_4 PF12799.7 CAM42877.1 - 8.5e-15 54.6 7.6 0.00016 22.0 0.5 4.4 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM42877.1 - 4.5e-12 45.6 10.3 2e-08 33.9 2.7 4.7 4 1 0 4 4 4 2 Leucine rich repeat LRR_9 PF14580.6 CAM42877.1 - 0.0041 16.7 0.0 4.2 6.8 0.1 2.7 2 1 0 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 CAM42877.1 - 0.016 15.2 2.0 5.5 7.3 0.0 3.8 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 CAM42877.1 - 0.13 12.9 3.7 20 6.2 0.2 5.0 4 2 0 4 4 4 0 Leucine Rich Repeat 4PPT_N PF17837.1 CAM42878.1 - 0.002 18.2 1.0 0.002 18.2 1.0 2.2 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase N-terminal domain RRM_1 PF00076.22 CAM42879.1 - 1.6e-07 31.0 1.0 0.0011 18.8 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CAM42879.1 - 0.013 15.1 0.0 0.25 11.0 0.0 2.1 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2967 PF11179.8 CAM42879.1 - 0.016 13.3 3.7 0.025 12.7 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) RRM_9 PF18444.1 CAM42879.1 - 0.15 11.9 0.1 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif Cyclin_N PF00134.23 CAM42880.1 - 3e-08 33.4 1.6 9.3e-08 31.9 0.4 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain RIC1 PF07064.13 CAM42881.1 - 1.4e-42 145.9 0.0 2.5e-42 145.0 0.0 1.4 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 CAM42881.1 - 0.025 14.9 0.0 0.78 10.1 0.0 3.3 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 CAM42882.1 - 1.6e-44 152.2 0.0 2.5e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM42882.1 - 1.2e-28 100.1 0.0 2.1e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CAM42882.1 - 0.018 15.0 0.0 0.041 13.8 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 CAM42882.1 - 0.054 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3772 PF12607.8 CAM42882.1 - 0.11 12.3 0.2 0.25 11.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3772) Pkinase_fungal PF17667.1 CAM42882.1 - 0.12 11.2 0.0 0.24 10.1 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 CAM42882.1 - 0.13 11.3 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.25 CAM42885.1 - 9e-50 169.5 0.0 1.5e-49 168.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM42885.1 - 1.1e-35 123.1 0.0 2.4e-35 122.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1356 PF07092.12 CAM42885.1 - 0.055 12.7 0.2 7.7 5.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1356) HemY_N PF07219.13 CAM42885.1 - 0.068 13.4 0.6 2.7 8.2 1.1 2.4 2 0 0 2 2 2 0 HemY protein N-terminus ARL17 PF15840.5 CAM42885.1 - 0.15 12.5 0.2 0.36 11.2 0.2 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor-like protein 17 DUF4383 PF14325.6 CAM42885.1 - 1.9 8.8 5.4 13 6.1 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4383) Cyclin PF08613.11 CAM42886.1 - 8.8e-24 84.7 0.4 1.2e-23 84.3 0.4 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CAM42886.1 - 4.7e-10 39.3 0.3 6e-10 39.0 0.3 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pex24p PF06398.11 CAM42887.2 - 0.0038 16.3 0.1 0.0063 15.5 0.1 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin RRM_8 PF11835.8 CAM42888.1 - 1.1e-07 32.0 0.0 2.5e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 RRM-like domain RRM_1 PF00076.22 CAM42888.1 - 0.0081 16.0 0.0 0.082 12.7 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 CAM42889.2 - 2.6e-10 40.0 0.0 0.0083 15.9 0.0 4.1 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 CAM42889.2 - 0.0078 16.4 0.0 0.025 14.8 0.0 1.8 1 1 0 1 1 1 1 RRM-like domain RRM_5 PF13893.6 CAM42889.2 - 0.041 13.5 0.0 7.7 6.1 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CAM42889.2 - 0.073 13.1 0.0 7 6.8 0.0 2.9 3 0 0 3 3 3 0 RNA binding motif RRM_occluded PF16842.5 CAM42889.2 - 0.15 11.9 0.0 0.81 9.6 0.0 2.1 2 0 0 2 2 2 0 Occluded RNA-recognition motif Tmemb_55A PF09788.9 CAM42890.2 - 0.0072 15.4 1.6 0.016 14.3 1.6 1.5 1 0 0 1 1 1 1 Transmembrane protein 55A tRNA-synt_2d PF01409.20 CAM42891.2 - 1e-79 267.5 0.1 1.4e-79 267.0 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD1 PF18552.1 CAM42891.2 - 7.8e-10 38.4 0.1 1.6e-09 37.4 0.1 1.5 1 0 0 1 1 1 1 PheRS DNA binding domain 1 PheRS_DBD3 PF18553.1 CAM42891.2 - 8e-08 32.5 0.2 1.9e-06 28.0 0.2 2.9 3 0 0 3 3 3 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 CAM42891.2 - 0.00043 19.8 0.0 0.52 9.7 0.0 2.6 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 CAM42891.2 - 0.0018 17.4 1.0 0.0033 16.6 0.2 1.8 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 CAM42891.2 - 0.0052 16.8 0.1 0.028 14.4 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) PheRS_DBD2 PF18554.1 CAM42891.2 - 0.055 13.5 0.2 0.11 12.4 0.2 1.6 1 0 0 1 1 1 0 PheRS DNA binding domain 2 Ribosomal_L18A PF01775.17 CAM42892.1 - 3.4e-40 136.9 1.2 4.5e-40 136.5 1.2 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A CTP_transf_like PF01467.26 CAM42893.1 - 4e-47 160.0 0.0 3.6e-26 92.1 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 CAM42893.1 - 9.9e-06 25.5 0.7 0.091 12.6 0.1 3.5 3 1 0 3 3 3 2 FAD synthetase CoA_binding_3 PF13727.6 CAM42893.1 - 0.096 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 CoA-binding domain Pantoate_ligase PF02569.15 CAM42893.1 - 0.15 11.2 0.2 0.53 9.4 0.0 1.9 2 0 0 2 2 2 0 Pantoate-beta-alanine ligase CENP-F_leu_zip PF10473.9 CAM42894.1 - 0.018 15.1 0.4 0.035 14.1 0.4 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Abhydrolase_6 PF12697.7 CAM42895.1 - 1.6e-15 58.3 0.0 1.9e-15 58.1 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CAM42895.1 - 6e-11 42.1 0.1 8.5e-11 41.6 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CAM42895.1 - 4.5e-06 26.5 0.0 6.7e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 CAM42895.1 - 0.0028 17.5 0.0 0.0065 16.3 0.0 1.6 2 0 0 2 2 2 1 Serine hydrolase Lipase_3 PF01764.25 CAM42895.1 - 0.011 15.6 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.7 CAM42895.1 - 0.025 14.4 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 CAM42895.1 - 0.028 13.3 0.0 0.076 11.9 0.0 1.6 2 0 0 2 2 2 0 Chlorophyllase enzyme Abhydrolase_9 PF10081.9 CAM42895.1 - 0.044 12.9 0.8 0.12 11.4 0.1 1.8 1 1 1 2 2 2 0 Alpha/beta-hydrolase family PGAP1 PF07819.13 CAM42895.1 - 0.097 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein V_ATPase_I PF01496.19 CAM42896.1 - 3.3e-246 819.2 0.6 4.6e-246 818.7 0.6 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DAO PF01266.24 CAM42897.1 - 7.1e-08 32.4 3.1 2.1e-06 27.6 0.4 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase GMC_oxred_N PF00732.19 CAM42897.1 - 2.8e-06 26.9 0.1 0.0032 16.9 0.0 3.0 2 1 0 2 2 2 2 GMC oxidoreductase FAD_binding_2 PF00890.24 CAM42897.1 - 6.8e-05 22.1 0.7 0.00053 19.2 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 CAM42897.1 - 0.0005 20.2 0.3 0.0016 18.6 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CAM42897.1 - 0.0023 17.2 0.1 0.0039 16.5 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 CAM42897.1 - 0.0031 16.4 0.1 0.005 15.7 0.1 1.3 1 0 0 1 1 1 1 Tryptophan halogenase NAD_binding_9 PF13454.6 CAM42897.1 - 0.0058 16.6 0.1 0.013 15.5 0.1 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 CAM42897.1 - 0.0087 15.1 0.2 0.014 14.5 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 CAM42897.1 - 0.037 12.7 0.1 0.051 12.3 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.21 CAM42897.1 - 0.047 13.0 1.5 0.048 13.0 0.2 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 CAM42897.1 - 0.1 11.6 0.1 0.16 11.0 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Hexapep_2 PF14602.6 CAM42897.1 - 8.8 6.2 7.3 0.46 10.3 1.1 2.1 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase CLASP_N PF12348.8 CAM42898.1 - 1.1e-13 51.4 0.7 1.1e-13 51.4 0.7 3.1 4 0 0 4 4 4 1 CLASP N terminal Cnd1 PF12717.7 CAM42898.1 - 0.0089 16.1 0.4 2.1 8.4 0.0 3.7 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 DUF5446 PF17522.2 CAM42898.1 - 0.11 12.7 0.1 0.29 11.3 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5446) HEAT PF02985.22 CAM42898.1 - 0.48 10.8 24.1 1.1 9.7 0.1 7.8 8 0 0 8 8 8 0 HEAT repeat UME PF08064.13 CAM42898.1 - 1.7 8.6 5.6 2.3 8.2 0.3 3.6 3 1 0 3 3 3 0 UME (NUC010) domain SNase PF00565.17 CAM42899.2 - 8.9e-52 174.1 1.2 2.5e-16 60.1 0.0 5.3 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 CAM42899.2 - 1.7e-16 60.3 0.0 3.1e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Tudor domain DUF4537 PF15057.6 CAM42899.2 - 0.0033 17.4 0.0 0.0089 16.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Agenet PF05641.12 CAM42899.2 - 0.11 13.0 0.1 0.66 10.5 0.0 2.4 3 0 0 3 3 3 0 Agenet domain UQ_con PF00179.26 CAM42900.1 - 2.6e-40 137.3 0.0 3.5e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF3630 PF12305.8 CAM42900.1 - 0.096 12.8 0.0 0.25 11.5 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3630) Peptidase_C2 PF00648.21 CAM42901.2 - 1.4e-06 27.6 0.0 6.1e-06 25.5 0.0 1.9 2 0 0 2 2 2 1 Calpain family cysteine protease RRM_1 PF00076.22 CAM42902.2 - 0.048 13.5 0.0 0.092 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Vps23_core PF09454.10 CAM42903.2 - 6.7e-17 61.2 0.1 1.7e-16 59.9 0.1 1.7 1 0 0 1 1 1 1 Vps23 core domain MHB PF16525.5 CAM42903.2 - 0.091 13.0 0.1 0.19 12.0 0.1 1.6 1 0 0 1 1 1 0 Haemophore, haem-binding CUE PF02845.16 CAM42903.2 - 0.16 11.7 1.2 0.91 9.3 0.1 2.4 1 1 1 2 2 2 0 CUE domain Cpn60_TCP1 PF00118.24 CAM42905.1 - 2.1e-151 504.9 2.0 2.4e-151 504.7 2.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Y_phosphatase2 PF03162.13 CAM42906.1 - 5.7e-22 78.0 0.0 9e-21 74.1 0.0 2.2 1 1 0 1 1 1 1 Tyrosine phosphatase family Ashwin PF15323.6 CAM42906.1 - 0.018 15.1 1.6 0.026 14.6 1.6 1.2 1 0 0 1 1 1 0 Developmental protein SSXRD PF09514.10 CAM42906.1 - 0.77 9.4 0.0 0.77 9.4 0.0 2.3 3 0 0 3 3 3 0 SSXRD motif Pkinase PF00069.25 CAM42907.1 - 1.4e-32 113.2 0.1 8.7e-26 90.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM42907.1 - 5e-17 62.0 0.2 9.5e-17 61.1 0.2 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 CAM42907.1 - 0.0003 20.5 0.0 0.0011 18.7 0.0 1.9 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CAM42907.1 - 0.011 14.6 0.0 0.019 13.7 0.0 1.5 1 1 0 1 1 1 0 Fungal protein kinase DUF747 PF05346.11 CAM42907.1 - 0.062 12.8 0.2 0.1 12.1 0.2 1.2 1 0 0 1 1 1 0 Eukaryotic membrane protein family Maf PF02545.14 CAM42908.1 - 3.5e-18 66.0 0.0 4e-18 65.8 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein ATP11 PF06644.11 CAM42908.1 - 0.0062 16.4 0.1 0.01 15.7 0.1 1.3 1 1 0 1 1 1 1 ATP11 protein HEPN_AbiU2 PF18734.1 CAM42908.1 - 0.06 12.8 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 AbiU2 LemA PF04011.12 CAM42909.2 - 0.096 12.5 3.6 2.1 8.2 1.5 2.7 2 0 0 2 2 2 0 LemA family TMF_DNA_bd PF12329.8 CAM42909.2 - 1.1 9.3 22.8 1.9 8.5 0.9 5.1 5 0 0 5 5 5 0 TATA element modulatory factor 1 DNA binding Metallophos_2 PF12850.7 CAM42910.1 - 1.7e-11 44.6 0.0 1.9e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain WD40 PF00400.32 CAM42911.1 - 4.6e-09 36.8 8.9 0.15 13.0 0.1 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM42911.1 - 0.00067 19.9 0.1 0.053 13.8 0.0 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain LSM PF01423.22 CAM42912.1 - 3.6e-14 52.2 0.1 4e-14 52.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CAM42912.1 - 0.00042 20.4 0.1 0.00047 20.2 0.1 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain HECT PF00632.25 CAM42914.1 - 1.9e-69 234.5 0.0 2.7e-69 234.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ZZ PF00569.17 CAM42914.1 - 0.00016 21.4 8.1 0.00016 21.4 8.1 2.2 2 0 0 2 2 2 1 Zinc finger, ZZ type Utp14 PF04615.13 CAM42914.1 - 0.022 13.4 0.9 0.04 12.5 0.9 1.3 1 0 0 1 1 1 0 Utp14 protein CRM1_C PF08767.11 CAM42915.1 - 9.1e-61 205.8 0.6 9.1e-61 205.8 0.6 2.9 4 0 0 4 4 4 1 CRM1 C terminal CRM1_repeat_2 PF18784.1 CAM42915.1 - 1.7e-26 91.7 1.2 5.2e-26 90.1 1.2 1.9 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 Xpo1 PF08389.12 CAM42915.1 - 2.6e-26 92.4 4.8 4.7e-26 91.6 1.2 3.3 3 0 0 3 3 3 1 Exportin 1-like protein CRM1_repeat_3 PF18787.1 CAM42915.1 - 2.3e-23 82.1 3.8 2.5e-23 81.9 1.4 2.4 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 CAM42915.1 - 1.6e-09 37.1 1.1 5.3e-09 35.5 1.1 1.9 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 CAM42915.1 - 1.1e-08 34.8 0.3 9.4e-08 31.9 0.3 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF4473 PF14747.6 CAM42915.1 - 0.0039 17.7 0.2 2.7 8.6 0.0 3.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4473) Mito_carr PF00153.27 CAM42916.2 - 1.2e-47 159.7 1.5 1.8e-15 56.6 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF4199 PF13858.6 CAM42916.2 - 0.063 13.7 0.4 0.13 12.7 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Mito_carr PF00153.27 CAM42917.1 - 8.7e-49 163.4 1.5 9.9e-16 57.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA_edit PF04073.15 CAM42920.1 - 2e-08 34.3 0.0 5.2e-08 33.0 0.0 1.7 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain DUF5473 PF17567.2 CAM42920.1 - 0.024 14.9 0.6 0.024 14.9 0.6 2.4 2 1 0 3 3 3 0 Family of unknown function (DUF5473) Sugarporin_N PF11471.8 CAM42920.1 - 0.2 11.6 3.1 0.21 11.6 1.4 1.9 1 1 0 1 1 1 0 Maltoporin periplasmic N-terminal extension T2SSM PF04612.12 CAM42920.1 - 0.58 10.2 3.9 0.19 11.8 1.3 1.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M Histone_H2A_C PF16211.5 CAM42921.1 - 2.9e-11 42.9 1.2 6.7e-11 41.7 1.2 1.7 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CAM42921.1 - 3.1e-06 27.6 0.1 5e-06 26.9 0.0 1.4 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 CAM42922.1 - 8.1e-12 44.7 1.5 1.9e-11 43.5 1.5 1.7 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CAM42922.1 - 3e-06 27.6 0.1 5e-06 26.9 0.0 1.4 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 PPR_2 PF13041.6 CAM42924.2 - 0.011 15.9 0.1 36 4.6 0.0 4.0 3 1 1 4 4 4 0 PPR repeat family ELO PF01151.18 CAM42926.1 - 5.3e-50 170.3 16.5 7.8e-50 169.7 16.5 1.2 1 0 0 1 1 1 1 GNS1/SUR4 family Ank_4 PF13637.6 CAM42928.2 - 2.5e-08 34.3 0.1 1.3e-07 32.0 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CAM42928.2 - 4e-07 30.5 0.0 1.5e-06 28.7 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CAM42928.2 - 1.5e-06 28.1 0.3 0.012 16.1 0.1 3.2 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 CAM42928.2 - 2.4e-06 27.7 1.2 0.05 14.1 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 CAM42928.2 - 6.8e-06 26.3 0.7 2e-05 24.7 0.7 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) T-box_assoc PF16176.5 CAM42929.2 - 0.29 11.2 2.1 1.8 8.6 0.1 2.6 3 0 0 3 3 3 0 T-box transcription factor-associated CSN8_PSD8_EIF3K PF10075.9 CAM42930.1 - 1e-26 93.6 0.0 1.7e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family HhH-GPD PF00730.25 CAM42930.1 - 0.16 12.5 0.0 0.4 11.2 0.0 1.7 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein PPR_2 PF13041.6 CAM42931.2 - 3.9e-42 142.2 17.6 9.4e-12 44.9 0.1 12.4 8 3 5 13 13 13 8 PPR repeat family PPR_3 PF13812.6 CAM42931.2 - 3.5e-28 97.5 8.0 2.7e-12 46.6 0.0 9.0 6 2 1 9 9 9 4 Pentatricopeptide repeat domain PPR_long PF17177.4 CAM42931.2 - 1.5e-17 63.7 12.7 6.2e-11 42.1 0.5 5.5 4 1 1 5 5 5 4 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 CAM42931.2 - 1.2e-15 56.5 11.6 3.6e-05 23.7 0.0 9.5 9 0 0 9 9 9 4 PPR repeat PPR_1 PF12854.7 CAM42931.2 - 2.1e-08 33.7 17.9 0.00065 19.3 0.0 8.8 10 0 0 10 10 10 2 PPR repeat COX5A PF02284.16 CAM42931.2 - 3.1e-05 23.9 1.7 0.17 11.9 0.0 3.6 2 1 1 3 3 3 2 Cytochrome c oxidase subunit Va ECSIT PF06239.11 CAM42931.2 - 0.00048 19.3 1.8 5.8 6.0 0.0 4.8 3 2 2 5 5 5 2 Evolutionarily conserved signalling intermediate in Toll pathway RPM2 PF08579.11 CAM42931.2 - 0.00072 20.0 3.2 4.9 7.6 0.0 4.9 2 2 1 3 3 3 2 Mitochondrial ribonuclease P subunit (RPM2) TPR_15 PF13429.6 CAM42931.2 - 0.047 12.9 0.2 0.14 11.4 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat PPP1R35_C PF15503.6 CAM42931.2 - 0.07 12.9 0.1 0.18 11.6 0.1 1.7 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 35 C-terminus Histone_HNS PF00816.21 CAM42932.1 - 0.54 11.1 3.3 0.73 10.7 0.3 2.8 2 0 0 2 2 2 0 H-NS histone family PilO PF04350.13 CAM42932.1 - 0.57 10.3 4.9 1 9.5 0.4 2.7 2 0 0 2 2 2 0 Pilus assembly protein, PilO ArfGap PF01412.18 CAM42933.1 - 1.2e-27 96.3 0.0 2.1e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Apolipoprotein PF01442.18 CAM42933.1 - 0.031 14.1 0.1 0.046 13.6 0.1 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain TF_Zn_Ribbon PF08271.12 CAM42933.1 - 0.12 11.9 2.1 0.24 11.0 2.1 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding PHTB1_C PF14728.6 CAM42934.2 - 2.7e-104 349.2 1.1 4e-104 348.7 1.1 1.2 1 0 0 1 1 1 1 PTHB1 C-terminus PHTB1_N PF14727.6 CAM42934.2 - 1.1e-89 301.7 0.0 1.6e-65 222.1 0.0 2.1 2 0 0 2 2 2 2 PTHB1 N-terminus BBS2_Mid PF14783.6 CAM42934.2 - 0.04 13.9 0.0 0.088 12.9 0.0 1.5 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region UCH PF00443.29 CAM42935.1 - 3.3e-32 112.0 0.0 4.7e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CAM42935.1 - 3.3e-13 49.9 0.1 7.4e-07 29.1 0.0 2.3 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Ipi1_N PF12333.8 CAM42935.1 - 0.051 14.2 0.0 0.12 13.0 0.0 1.6 1 0 0 1 1 1 0 Rix1 complex component involved in 60S ribosome maturation CRAL_TRIO PF00650.20 CAM42936.1 - 1.1e-35 122.7 0.0 1.6e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.6 CAM42936.1 - 0.00022 21.8 0.1 0.095 13.2 0.0 2.3 1 1 1 2 2 2 2 Golgi-dynamics membrane-trafficking CRAL_TRIO PF00650.20 CAM42937.1 - 4.6e-33 114.2 0.0 6.8e-33 113.6 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CAM42937.1 - 0.0017 18.5 0.0 0.0031 17.7 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CAM42937.1 - 0.0097 16.1 0.2 0.02 15.1 0.2 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO PF00650.20 CAM42938.2 - 4.6e-28 97.9 0.0 1.2e-27 96.6 0.0 1.7 1 1 0 1 1 1 1 CRAL/TRIO domain SHS2_Rpb7-N PF03876.17 CAM42939.1 - 1.2e-14 54.4 0.0 2e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Pkinase PF00069.25 CAM42940.1 - 8.1e-09 35.2 0.0 1.2e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM42940.1 - 3.8e-06 26.4 0.0 5.6e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CAM42940.1 - 0.00017 21.6 0.9 0.00032 20.7 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CAM42940.1 - 0.0046 16.6 0.0 0.0081 15.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Haspin_kinase PF12330.8 CAM42940.1 - 0.012 14.6 0.0 0.021 13.8 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pep_deformylase PF01327.21 CAM42941.1 - 4.8e-26 91.3 0.0 7.3e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 Polypeptide deformylase WLM PF08325.10 CAM42942.2 - 2.7e-32 112.4 0.0 3.9e-30 105.4 0.0 2.4 2 1 0 2 2 2 1 WLM domain DUF45 PF01863.17 CAM42942.2 - 0.0034 17.4 1.2 0.0057 16.7 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF45 RecR PF02132.15 CAM42942.2 - 0.021 14.4 3.1 0.072 12.7 3.1 1.8 1 0 0 1 1 1 0 RecR protein OrfB_Zn_ribbon PF07282.11 CAM42942.2 - 0.37 10.8 2.0 1 9.3 2.0 1.8 1 0 0 1 1 1 0 Putative transposase DNA-binding domain VSG_B PF13206.6 CAM42943.2 - 6.3 5.9 15.4 0.23 10.7 9.3 1.7 2 0 0 2 2 2 0 Trypanosomal VSG domain Peptidase_C97 PF05903.14 CAM42944.2 - 9.8e-19 67.7 0.0 1.9e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain CPSF_A PF03178.15 CAM42945.2 - 1.1e-64 218.7 0.0 1.9e-64 218.1 0.0 1.4 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 CAM42945.2 - 1.4e-17 63.6 0.0 2.4e-13 49.6 0.0 3.3 2 1 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term LicD PF04991.13 CAM42946.1 - 2.9e-08 34.1 0.0 4.8e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 LicD family SP_C-Propep PF08999.10 CAM42946.1 - 0.017 14.9 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide mRNA_cap_enzyme PF01331.19 CAM42947.2 - 2.2e-08 34.1 0.0 4.1e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain ADK PF00406.22 CAM42947.2 - 1.9e-07 31.3 0.0 1.4e-06 28.5 0.0 2.1 1 1 1 2 2 2 1 Adenylate kinase AAA_17 PF13207.6 CAM42947.2 - 2.8e-07 31.0 0.0 1.8e-06 28.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain mRNA_cap_C PF03919.15 CAM42947.2 - 1.4e-06 28.9 0.0 5.6e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 mRNA capping enzyme, C-terminal domain AAA_18 PF13238.6 CAM42947.2 - 7e-06 26.6 0.0 1.7e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CAM42947.2 - 0.0011 19.2 0.1 0.0066 16.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 CAM42947.2 - 0.0021 17.8 0.0 0.85 9.3 0.0 2.4 1 1 0 2 2 2 2 Thymidylate kinase AAA_22 PF13401.6 CAM42947.2 - 0.0064 16.8 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CAM42947.2 - 0.021 14.1 0.0 0.42 9.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_14 PF13173.6 CAM42947.2 - 0.029 14.4 0.0 0.055 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CAM42947.2 - 0.041 13.6 0.0 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 CAM42947.2 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 CAM42947.2 - 0.12 12.6 0.0 0.33 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CAM42948.1 - 0.0082 16.3 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CAM42948.1 - 0.013 16.0 0.0 0.025 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 CAM42948.1 - 0.064 13.7 0.0 0.19 12.2 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CAM42948.1 - 0.068 13.6 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain IPT PF01745.16 CAM42948.1 - 0.15 11.5 0.0 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 Isopentenyl transferase PAM2 PF07145.15 CAM42948.1 - 0.25 11.1 3.7 0.78 9.6 1.5 2.5 2 0 0 2 2 2 0 Ataxin-2 C-terminal region Uds1 PF15456.6 CAM42949.1 - 1.2 9.4 3.6 6.4 7.0 1.0 2.1 1 1 0 2 2 2 0 Up-regulated During Septation DEAD PF00270.29 CAM42951.2 - 9.3e-21 74.4 0.1 3.6e-20 72.5 0.1 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Sec63 PF02889.16 CAM42951.2 - 4.9e-19 68.5 0.2 3.2e-16 59.3 0.0 2.7 3 0 0 3 3 3 2 Sec63 Brl domain ResIII PF04851.15 CAM42951.2 - 1.1e-06 28.7 0.0 2.8e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CAM42951.2 - 2.7e-06 27.7 0.0 1.8e-05 25.1 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain T2SSE PF00437.20 CAM42951.2 - 0.013 14.5 0.4 0.066 12.3 0.0 2.2 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_22 PF13401.6 CAM42951.2 - 0.11 12.7 0.0 11 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain Cyclase PF04199.13 CAM42952.1 - 7e-10 39.3 0.0 4e-09 36.8 0.0 2.0 1 1 0 1 1 1 1 Putative cyclase CDC45 PF02724.14 CAM42954.1 - 2.7 6.2 5.6 3.9 5.6 5.6 1.2 1 0 0 1 1 1 0 CDC45-like protein PI3_PI4_kinase PF00454.27 CAM42957.2 - 2.5e-44 152.0 0.1 4.4e-44 151.2 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 CAM42957.2 - 2e-10 40.3 0.7 2e-10 40.3 0.7 2.5 3 0 0 3 3 3 1 FATC domain FAT PF02259.23 CAM42957.2 - 1.3e-08 34.5 1.3 3.2e-06 26.6 1.3 3.4 1 1 0 1 1 1 1 FAT domain UME PF08064.13 CAM42957.2 - 0.13 12.2 0.3 0.97 9.4 0.0 2.7 2 0 0 2 2 2 0 UME (NUC010) domain MIP-T3 PF10243.9 CAM42958.1 - 4.8e-27 94.2 0.3 8.3e-27 93.4 0.0 1.5 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 CH-like domain rRNA_processing PF08524.11 CAM42960.1 - 8.3e-11 42.1 33.0 1.3e-09 38.2 33.0 2.1 1 1 0 1 1 1 1 rRNA processing TEX13 PF15186.6 CAM42960.1 - 1.1 9.0 15.0 1.9 8.2 1.2 2.3 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family DUF4407 PF14362.6 CAM42960.1 - 3.4 7.0 16.6 4.1 6.7 16.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ALMT PF11744.8 CAM42960.1 - 6.9 5.4 13.0 8.3 5.1 13.0 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter CENP-L PF13092.6 CAM42961.2 - 0.023 14.9 0.0 0.042 14.1 0.0 1.5 1 0 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 DUF4228 PF14009.6 CAM42961.2 - 0.031 14.7 0.2 0.17 12.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) Peptidase_M41 PF01434.18 CAM42962.1 - 5.9e-46 156.7 0.3 5.9e-46 156.7 0.3 1.6 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 CAM42962.1 - 7.6e-41 139.6 0.0 1.5e-40 138.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CAM42962.1 - 6.6e-05 23.4 0.1 0.00088 19.7 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CAM42962.1 - 0.0022 18.3 0.2 0.029 14.6 0.2 2.6 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 CAM42962.1 - 0.0099 15.1 0.1 0.023 13.9 0.0 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 CAM42962.1 - 0.013 15.2 0.0 0.036 13.8 0.0 1.8 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CAM42962.1 - 0.019 15.0 0.3 0.11 12.6 0.1 2.3 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 CAM42962.1 - 0.039 13.6 0.0 0.21 11.3 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 CAM42962.1 - 0.042 13.1 0.0 0.096 12.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.17 CAM42962.1 - 0.065 13.0 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_lid_3 PF17862.1 CAM42962.1 - 0.082 12.7 0.0 0.25 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA+ lid domain DUF2075 PF09848.9 CAM42962.1 - 0.085 12.1 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 CAM42962.1 - 0.17 11.8 0.1 0.67 9.9 0.1 1.9 2 0 0 2 2 2 0 NACHT domain AAA_2 PF07724.14 CAM42962.1 - 0.18 11.9 0.6 2.3 8.3 0.4 2.6 1 1 1 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 CAM42962.1 - 0.18 11.5 0.1 1 9.0 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 CAM42962.1 - 0.23 10.9 0.7 1.8 8.1 0.1 2.5 2 1 0 2 2 2 0 P-loop containing dynein motor region Pex14_N PF04695.13 CAM42962.1 - 4.1 8.0 10.9 0.45 11.2 5.4 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region YqaJ PF09588.10 CAM42964.2 - 1.8e-51 174.2 0.0 3e-51 173.5 0.0 1.4 1 0 0 1 1 1 1 YqaJ-like viral recombinase domain DUF5039 PF16442.5 CAM42965.1 - 0.082 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5039) NUDIX PF00293.28 CAM42966.1 - 6.4e-12 45.7 0.5 8e-11 42.1 0.5 2.0 1 1 0 1 1 1 1 NUDIX domain PSP1 PF04468.12 CAM42967.2 - 1.9e-22 79.3 1.3 3.2e-22 78.6 1.3 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region eIF3_p135 PF12807.7 CAM42968.2 - 4.8e-11 43.0 0.0 8.9e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 CLU PF13236.6 CAM42968.2 - 6.1e-09 36.0 0.0 9.9e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Clustered mitochondria ArfGap PF01412.18 CAM42969.2 - 9.5e-40 135.3 0.2 1.6e-39 134.6 0.2 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PMI_typeI PF01238.21 CAM42970.1 - 1.2e-91 307.8 0.0 1.3e-91 307.6 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I PIF1 PF05970.14 CAM42971.1 - 5.1e-38 131.2 1.2 8.3e-16 58.1 0.0 4.5 4 0 0 4 4 4 4 PIF1-like helicase AAA_30 PF13604.6 CAM42971.1 - 1.7e-14 54.0 0.0 6.6e-13 48.8 0.0 3.2 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.6 CAM42971.1 - 9.7e-06 26.0 0.0 0.00014 22.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CAM42971.1 - 0.0002 21.8 0.1 0.00087 19.7 0.1 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CAM42971.1 - 0.00098 19.4 0.3 0.09 13.1 0.0 2.8 3 0 0 3 3 2 1 AAA domain NTPase_1 PF03266.15 CAM42971.1 - 0.0011 18.9 0.1 0.29 11.0 0.0 2.4 2 0 0 2 2 2 1 NTPase AAA_5 PF07728.14 CAM42971.1 - 0.0012 18.8 0.1 0.041 13.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 CAM42971.1 - 0.0015 18.3 0.5 0.46 10.2 0.1 3.2 3 0 0 3 3 3 1 IstB-like ATP binding protein UvrD_C_2 PF13538.6 CAM42971.1 - 0.0028 17.5 0.0 0.0083 15.9 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA PF00004.29 CAM42971.1 - 0.0051 17.2 0.0 0.049 14.1 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 CAM42971.1 - 0.01 15.6 0.1 5.8 6.6 0.0 3.5 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 CAM42971.1 - 0.011 15.0 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Herpes_Helicase PF02689.14 CAM42971.1 - 0.014 13.4 0.6 2 6.2 0.5 2.3 2 0 0 2 2 2 0 Helicase SH3_13 PF18335.1 CAM42971.1 - 0.022 14.6 0.0 0.054 13.3 0.0 1.6 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain MeaB PF03308.16 CAM42971.1 - 0.052 12.5 0.1 0.15 11.0 0.1 1.7 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 CAM42971.1 - 0.064 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.16 CAM42971.1 - 0.065 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Helicase_RecD PF05127.14 CAM42971.1 - 0.08 12.8 1.1 1.1 9.1 1.1 2.4 1 1 0 1 1 1 0 Helicase DEAD PF00270.29 CAM42971.1 - 0.15 11.8 0.1 15 5.3 0.1 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase ABC_tran PF00005.27 CAM42971.1 - 0.19 12.2 0.3 0.58 10.7 0.3 1.8 1 0 0 1 1 1 0 ABC transporter DUF2075 PF09848.9 CAM42971.1 - 0.37 10.0 1.8 1.2 8.2 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PIN_11 PF18479.1 CAM42973.1 - 0.014 15.6 0.1 0.56 10.4 0.1 2.4 2 0 0 2 2 2 0 PIN like domain FlgT_N PF16548.5 CAM42976.1 - 0.093 13.3 1.1 0.18 12.4 1.1 1.5 1 0 0 1 1 1 0 Flagellar assembly protein T, N-terminal domain NAD_synthase PF02540.17 CAM42979.1 - 2.5e-32 111.9 0.0 3e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 CAM42979.1 - 0.16 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase PAPS_reduct PF01507.19 CAM42979.1 - 0.18 11.8 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family PP2C PF00481.21 CAM42981.2 - 5.3e-68 229.4 0.0 7.6e-68 228.9 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Pex14_N PF04695.13 CAM42981.2 - 7.6 7.2 8.0 0.67 10.6 1.4 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SpoU_methylase PF00588.19 CAM42983.2 - 1.1e-10 41.8 0.0 0.015 15.5 0.0 3.9 4 0 0 4 4 4 3 SpoU rRNA Methylase family DNA_pol_E_B PF04042.16 CAM42984.2 - 2.7e-12 46.5 0.1 1.1e-10 41.3 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase alpha/epsilon subunit B Coatomer_E PF04733.14 CAM42985.2 - 1.3e-30 106.9 5.1 4.6e-23 82.0 2.3 2.0 2 0 0 2 2 2 2 Coatomer epsilon subunit TPR_14 PF13428.6 CAM42985.2 - 3.1e-05 24.4 10.6 0.98 10.4 0.0 5.4 3 2 1 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 CAM42985.2 - 5.5e-05 23.0 4.7 0.72 10.1 0.0 5.8 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 CAM42985.2 - 0.00043 20.3 2.1 0.11 12.7 0.0 4.8 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 CAM42985.2 - 0.0047 17.2 9.7 0.041 14.2 3.1 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 CAM42985.2 - 0.016 15.1 4.0 6.6 6.7 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CAM42985.2 - 0.022 14.6 5.0 0.48 10.3 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 CAM42985.2 - 0.044 14.3 14.3 0.66 10.5 0.9 4.5 3 2 2 5 5 5 0 Tetratricopeptide repeat OstA_2 PF13100.6 CAM42985.2 - 0.047 13.3 0.1 1.1 8.8 0.0 2.4 2 1 1 3 3 3 0 OstA-like protein TPR_4 PF07721.14 CAM42985.2 - 0.063 13.9 2.7 11 7.0 0.1 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 CAM42985.2 - 6.5 7.5 18.8 0.23 12.1 3.5 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat WW PF00397.26 CAM42986.1 - 2.8e-12 46.5 0.8 4.3e-12 45.9 0.8 1.3 1 0 0 1 1 1 1 WW domain zf-CCCH PF00642.24 CAM42986.1 - 6.1e-06 26.0 0.8 1.1e-05 25.2 0.8 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CAM42986.1 - 0.00025 21.0 1.4 0.00025 21.0 1.4 1.8 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_4 PF18044.1 CAM42986.1 - 0.0023 17.7 0.8 0.0023 17.7 0.8 1.8 2 0 0 2 2 2 1 CCCH-type zinc finger Torus PF16131.5 CAM42986.1 - 0.0082 16.8 0.2 0.0096 16.6 0.2 1.2 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 CAM42986.1 - 0.051 14.1 0.5 0.14 12.7 0.5 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger PUF PF00806.19 CAM42987.1 - 1.5e-19 68.5 0.0 0.049 13.4 0.0 8.9 10 0 0 10 10 10 6 Pumilio-family RNA binding repeat UTP15_C PF09384.10 CAM42987.1 - 2.2 7.9 6.2 1.7 8.3 0.1 3.2 3 1 0 3 3 3 0 UTP15 C terminal DGF-1_C PF11040.8 CAM42987.1 - 2.4 8.2 5.5 8.6 6.4 3.9 2.6 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DAZAP2 PF11029.8 CAM42989.2 - 0.02 15.8 0.2 0.08 13.9 0.2 2.1 1 0 0 1 1 1 0 DAZ associated protein 2 (DAZAP2) DUF4662 PF15578.6 CAM42992.2 - 0.094 12.5 1.8 0.094 12.5 1.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4662) CDC45 PF02724.14 CAM42993.1 - 0.097 11.0 1.4 0.097 11.0 1.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.25 CAM42994.2 - 2.3e-46 158.3 0.0 2.7e-44 151.5 0.0 2.6 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM42994.2 - 1.1e-30 106.8 0.0 4.1e-30 104.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 CAM42994.2 - 9.3e-08 32.5 0.0 1.7e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 CAM42994.2 - 0.004 17.5 0.0 0.0094 16.3 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.6 CAM42994.2 - 0.0096 15.3 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Sod_Fe_C PF02777.18 CAM42995.1 - 1.5e-38 131.0 0.3 3.1e-38 130.1 0.1 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CAM42995.1 - 5.5e-21 74.8 0.1 2.5e-20 72.7 0.1 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain GH101_N PF17995.1 CAM42995.1 - 0.04 13.6 0.0 0.073 12.7 0.0 1.4 1 0 0 1 1 1 0 Endo-alpha-N-acetylgalactosaminidase N-terminal Sod_Fe_C PF02777.18 CAM42996.1 - 1.4e-38 131.1 0.2 2.9e-38 130.1 0.1 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CAM42996.1 - 1e-20 74.0 0.5 2.9e-20 72.5 0.1 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain GH101_N PF17995.1 CAM42996.1 - 0.043 13.4 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 Endo-alpha-N-acetylgalactosaminidase N-terminal Ras PF00071.22 CAM42997.1 - 5.7e-36 123.6 0.0 6.9e-36 123.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAM42997.1 - 3.9e-32 111.0 0.0 5.6e-32 110.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAM42997.1 - 3.6e-10 39.6 0.0 4.8e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CAM42997.1 - 9.6e-07 28.4 0.0 1.2e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CAM42997.1 - 1.1e-06 28.3 0.0 0.00017 21.2 0.0 2.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CAM42997.1 - 1.3e-05 24.7 0.0 2.3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CAM42997.1 - 1.4e-05 25.1 0.0 2.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase TniB PF05621.11 CAM42997.1 - 0.00046 19.7 0.0 0.025 14.0 0.0 2.4 3 0 0 3 3 3 1 Bacterial TniB protein ATP_bind_1 PF03029.17 CAM42997.1 - 0.00056 19.8 0.1 0.00088 19.1 0.0 1.4 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1_Xtn PF16897.5 CAM42997.1 - 0.0021 18.0 0.0 0.0039 17.2 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 CAM42997.1 - 0.0036 17.2 0.0 2.1 8.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MCM PF00493.23 CAM42997.1 - 0.063 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_16 PF13191.6 CAM42997.1 - 0.075 13.4 0.0 0.23 11.8 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain Cpn60_TCP1 PF00118.24 CAM42998.2 - 7e-83 278.9 5.4 1.5e-82 277.8 5.4 1.5 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cation_efflux PF01545.21 CAM43000.2 - 3.3e-06 27.0 8.6 6.2e-06 26.1 8.6 1.4 1 1 0 1 1 1 1 Cation efflux family COX7C PF02935.16 CAM43000.2 - 0.21 11.9 1.1 0.79 10.0 1.1 2.0 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc TRP PF06011.12 CAM43000.2 - 0.6 8.8 5.7 2.8 6.6 0.1 2.1 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel CBFD_NFYB_HMF PF00808.23 CAM43001.1 - 0.00041 20.6 0.0 0.00065 19.9 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PliI PF16743.5 CAM43001.1 - 0.065 13.0 0.0 0.079 12.7 0.0 1.2 1 0 0 1 1 1 0 Periplasmic lysozyme inhibitor of I-type lysozyme GHMP_kinases_N PF00288.26 CAM43003.2 - 0.025 14.8 0.6 0.35 11.1 0.1 3.1 2 0 0 2 2 2 0 GHMP kinases N terminal domain DUF647 PF04884.14 CAM43006.1 - 3.2e-32 112.1 9.4 5e-32 111.4 9.4 1.3 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DUF745 PF05335.13 CAM43007.1 - 0.0069 16.1 4.8 0.0069 16.1 4.8 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF745) SpoOE-like PF09388.10 CAM43007.1 - 0.21 11.5 1.4 13 5.7 0.2 2.5 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein WDCP PF15390.6 CAM43007.1 - 0.21 9.9 7.2 0.38 9.1 5.7 1.8 1 1 1 2 2 2 0 WD repeat and coiled-coil-containing protein family GED PF02212.18 CAM43007.1 - 1.4 9.2 6.4 0.58 10.3 2.0 2.4 2 0 0 2 2 2 0 Dynamin GTPase effector domain DnaJ_C PF01556.18 CAM43008.1 - 1.3e-32 113.0 0.0 1.8e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CAM43008.1 - 1.7e-15 56.9 0.5 2.6e-15 56.3 0.5 1.3 1 0 0 1 1 1 1 DnaJ domain Acyltransferase PF01553.21 CAM43010.2 - 1.7e-14 53.6 0.2 8.4e-14 51.3 0.0 2.0 2 0 0 2 2 2 1 Acyltransferase Lipase_GDSL_3 PF14606.6 CAM43010.2 - 0.15 12.2 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Nop25 PF09805.9 CAM43013.1 - 0.042 14.3 5.3 0.049 14.1 5.3 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Evr1_Alr PF04777.13 CAM43013.1 - 0.11 13.0 1.1 0.18 12.3 0.7 1.6 1 1 0 1 1 1 0 Erv1 / Alr family DUF4200 PF13863.6 CAM43014.1 - 9.6e-23 80.8 14.4 9.6e-23 80.8 14.4 3.9 4 0 0 4 4 4 2 Domain of unknown function (DUF4200) DUF2730 PF10805.8 CAM43014.1 - 3.2 7.9 9.6 25 5.0 0.4 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2730) Endosulfine PF04667.17 CAM43015.1 - 0.00024 21.1 4.2 0.00042 20.4 4.2 1.5 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region DUF3456 PF11938.8 CAM43016.1 - 9e-26 91.3 0.4 5.5e-25 88.7 0.1 1.9 2 0 0 2 2 2 1 TLR4 regulator and MIR-interacting MSAP PEHE PF15275.6 CAM43016.1 - 2.1 9.0 4.9 0.57 10.8 0.8 2.0 2 0 0 2 2 2 0 PEHE domain MIR PF02815.19 CAM43017.1 - 0.035 13.9 0.0 0.068 13.0 0.0 1.5 1 0 0 1 1 1 0 MIR domain EMP24_GP25L PF01105.24 CAM43018.1 - 1.4e-31 109.9 0.1 1.5e-31 109.7 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ras PF00071.22 CAM43019.1 - 6.4e-61 204.7 0.0 7.7e-61 204.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAM43019.1 - 8.7e-33 113.1 0.0 1.6e-32 112.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAM43019.1 - 4e-12 45.9 0.0 4.8e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CAM43019.1 - 0.00015 21.7 0.0 0.21 11.5 0.0 2.6 2 1 1 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 CAM43019.1 - 0.00026 21.1 0.0 0.00066 19.7 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CAM43019.1 - 0.00068 19.2 0.0 0.0029 17.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CAM43019.1 - 0.0012 18.2 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 CAM43019.1 - 0.038 14.3 0.0 0.1 12.9 0.0 1.8 2 1 0 2 2 2 0 AAA domain DAP3 PF10236.9 CAM43019.1 - 0.04 13.1 0.0 0.063 12.4 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_24 PF13479.6 CAM43019.1 - 0.14 11.9 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain TetR_C_16 PF17920.1 CAM43019.1 - 0.15 12.3 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain NECFESHC PF16621.5 CAM43020.2 - 0.0052 16.7 0.3 0.023 14.6 0.3 2.2 1 0 0 1 1 1 1 SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1 DUF5617 PF18493.1 CAM43021.1 - 0.0048 17.0 0.1 0.0066 16.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5617) ABC_tran PF00005.27 CAM43022.1 - 4.2e-18 66.2 0.0 8.2e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CAM43022.1 - 1.7e-09 37.9 0.1 2.4e-05 24.3 0.3 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CAM43022.1 - 9.5e-08 31.7 0.0 8e-06 25.4 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_membrane PF00664.23 CAM43022.1 - 1e-06 28.7 8.6 1.8e-06 27.8 8.6 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_16 PF13191.6 CAM43022.1 - 0.00074 19.9 0.1 0.0023 18.3 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 CAM43022.1 - 0.0019 18.2 0.3 0.0067 16.4 0.1 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 CAM43022.1 - 0.0072 16.6 1.6 0.016 15.5 0.2 2.2 3 0 0 3 3 2 1 AAA domain AAA_23 PF13476.6 CAM43022.1 - 0.012 16.1 0.0 0.019 15.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CAM43022.1 - 0.02 14.5 1.2 0.34 10.5 0.8 2.9 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 CAM43022.1 - 0.033 14.6 0.1 0.24 11.8 0.0 2.5 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 CAM43022.1 - 0.046 13.5 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Adeno_IVa2 PF02456.15 CAM43022.1 - 0.061 12.1 0.1 0.11 11.3 0.1 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein Rad17 PF03215.15 CAM43022.1 - 0.064 13.2 0.4 0.14 12.1 0.4 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain RNA_helicase PF00910.22 CAM43022.1 - 0.07 13.5 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase SbcCD_C PF13558.6 CAM43022.1 - 0.079 13.2 0.1 1.2 9.4 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Creatininase PF02633.14 CAM43022.1 - 0.083 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Creatinine amidohydrolase AAA_15 PF13175.6 CAM43022.1 - 0.22 11.2 0.0 12 5.5 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain ATPase_2 PF01637.18 CAM43022.1 - 0.24 11.3 0.1 0.54 10.1 0.1 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea CTP_transf_like PF01467.26 CAM43023.1 - 1.4e-07 31.8 0.0 2.9e-07 30.8 0.0 1.5 1 1 0 1 1 1 1 Cytidylyltransferase-like dCMP_cyt_deam_1 PF00383.23 CAM43024.1 - 1.4e-07 31.3 0.1 3e-07 30.2 0.1 1.7 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CAM43024.1 - 1.9e-06 27.7 0.0 3.7e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 CAM43024.1 - 0.0072 16.4 0.3 0.058 13.5 0.0 2.4 3 0 0 3 3 3 1 Bd3614-like deaminase Methyltransf_31 PF13847.6 CAM43025.1 - 0.17 11.7 0.1 16 5.3 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Cons_hypoth95 PF03602.15 CAM43025.1 - 0.19 11.3 0.0 0.56 9.8 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical protein 95 MAD PF05557.13 CAM43026.1 - 0.014 13.8 14.9 0.0077 14.7 10.9 2.0 2 0 0 2 2 2 0 Mitotic checkpoint protein DUF1192 PF06698.11 CAM43026.1 - 0.019 15.0 2.1 0.99 9.5 0.2 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) MbeD_MobD PF04899.12 CAM43026.1 - 0.12 12.5 6.1 0.067 13.3 1.9 2.7 2 0 0 2 2 2 0 MbeD/MobD like DMPK_coil PF08826.10 CAM43026.1 - 3.1 8.0 8.0 8 6.7 0.3 3.4 2 0 0 2 2 2 0 DMPK coiled coil domain like Fungal_TACC PF12709.7 CAM43026.1 - 4.3 7.8 10.4 15 6.1 0.2 4.2 4 1 1 5 5 5 0 Fungal Transforming acidic coiled-coil (TACC) proteins LEA_3 PF03242.13 CAM43027.1 - 1.7 9.5 5.8 1.8 9.3 3.8 2.0 2 0 0 2 2 2 0 Late embryogenesis abundant protein DUF2933 PF11666.8 CAM43028.1 - 0.3 11.2 4.1 1.2 9.2 4.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2933) RRM_1 PF00076.22 CAM43029.1 - 1.4e-06 28.0 0.0 2.5e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.6 CAM43029.1 - 9.3e-05 22.8 0.1 9.3e-05 22.8 0.1 2.2 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 CAP_N PF01213.19 CAM43029.1 - 4.4 6.7 13.5 0.76 9.2 8.5 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Importin_rep_4 PF18808.1 CAM43031.2 - 5.1e-16 58.7 0.9 2.9e-13 49.9 0.0 4.1 4 0 0 4 4 4 1 Importin repeat HEAT_EZ PF13513.6 CAM43031.2 - 1.2e-11 44.8 3.2 0.46 11.0 0.0 6.6 6 0 0 6 6 6 4 HEAT-like repeat HEAT PF02985.22 CAM43031.2 - 1.6e-06 27.9 10.6 0.27 11.6 0.0 7.5 7 0 0 7 7 7 2 HEAT repeat Cnd1 PF12717.7 CAM43031.2 - 9.9e-06 25.7 0.3 0.00045 20.3 0.0 2.7 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CAM43031.2 - 3e-05 24.3 0.6 0.024 15.0 0.0 4.8 5 1 0 5 5 5 1 HEAT repeats RTP1_C1 PF10363.9 CAM43031.2 - 0.00032 20.8 3.1 0.66 10.2 0.0 4.7 4 1 1 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 MMS19_C PF12460.8 CAM43031.2 - 0.31 10.1 4.0 37 3.2 0.3 4.0 5 0 0 5 5 5 0 RNAPII transcription regulator C-terminal CSN8_PSD8_EIF3K PF10075.9 CAM43035.1 - 1.9e-15 57.1 0.0 3.2e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family PCI PF01399.27 CAM43035.1 - 0.0039 17.7 0.0 0.0057 17.1 0.0 1.4 1 0 0 1 1 1 1 PCI domain FPL PF09758.9 CAM43035.1 - 0.089 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein DUF3378 PF11858.8 CAM43035.1 - 0.16 12.1 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3378) PilP PF04351.13 CAM43036.1 - 0.16 11.9 1.2 1 9.3 1.4 2.2 2 0 0 2 2 2 0 Pilus assembly protein, PilP GTP_EFTU PF00009.27 CAM43037.2 - 1.4e-25 90.0 0.0 2.2e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CAM43037.2 - 4.6e-16 58.6 0.0 9.7e-16 57.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CAM43037.2 - 1.6e-07 31.3 0.0 3.4e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CAM43037.2 - 1.3e-06 28.4 0.0 2.7e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CAM43037.2 - 1.2e-05 25.4 0.2 0.14 12.2 0.0 2.6 1 1 1 2 2 2 2 Dynamin family EFG_IV PF03764.18 CAM43037.2 - 0.00019 21.2 0.0 0.00044 20.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV Septin PF00735.18 CAM43037.2 - 0.00026 20.4 0.0 0.00042 19.7 0.0 1.2 1 0 0 1 1 1 1 Septin Roc PF08477.13 CAM43037.2 - 0.00045 20.4 0.0 0.0011 19.1 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CAM43037.2 - 0.0026 17.2 0.0 0.0045 16.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CAM43037.2 - 0.007 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Ras family AIG1 PF04548.16 CAM43037.2 - 0.036 13.4 0.1 0.3 10.4 0.0 2.1 2 0 0 2 2 2 0 AIG1 family TniB PF05621.11 CAM43037.2 - 0.06 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein EFTUD2 PF16004.5 CAM43037.2 - 0.07 13.7 2.8 3.1 8.4 2.8 2.3 1 1 0 1 1 1 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus RsgA_GTPase PF03193.16 CAM43037.2 - 0.15 11.9 0.3 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Complex1_LYR PF05347.15 CAM43038.1 - 2.4e-12 46.7 0.3 2.4e-12 46.7 0.3 1.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 CAM43038.1 - 0.00069 20.2 0.2 0.0017 18.9 0.2 1.6 1 0 0 1 1 1 1 Complex1_LYR-like HHV-1_VABD PF16852.5 CAM43039.1 - 0.15 12.1 30.5 1.1e+02 3.0 0.1 9.8 9 0 0 9 9 9 0 Herpes viral adaptor-to-host cellular mRNA binding domain SpoOE-like PF09388.10 CAM43039.1 - 1 9.3 6.7 2.6 8.0 0.9 3.2 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein DEAD PF00270.29 CAM43040.1 - 7.8e-41 139.8 0.1 2e-40 138.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAM43040.1 - 6.2e-24 84.5 0.0 1.6e-23 83.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CAM43040.1 - 3.9e-14 52.6 0.2 1.3e-13 50.9 0.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CAM43040.1 - 0.059 13.4 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Formyl_trans_N PF00551.19 CAM43041.1 - 1.6e-15 57.3 0.0 2.9e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase CS PF04969.16 CAM43044.1 - 0.0046 17.9 0.0 0.0082 17.1 0.0 1.4 1 0 0 1 1 1 1 CS domain PAP2 PF01569.21 CAM43047.1 - 7.4e-18 64.6 3.1 7.4e-18 64.6 3.1 2.1 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 CAM43047.1 - 0.00045 20.0 2.9 0.00045 20.0 2.9 2.8 4 0 0 4 4 4 1 PAP2 superfamily Big_4 PF07532.11 CAM43048.1 - 0.18 11.5 1.4 0.42 10.4 0.2 2.1 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 4) ATG16 PF08614.11 CAM43048.1 - 2.9 8.1 16.3 6.4 7.0 10.7 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) ERG4_ERG24 PF01222.17 CAM43050.1 - 1.1e-124 416.5 2.0 1.2e-124 416.3 2.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 CAM43050.1 - 1.4e-07 31.3 0.1 3.3e-07 30.1 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 CAM43050.1 - 0.00049 20.4 0.0 0.0018 18.7 0.0 2.0 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.14 CAM43050.1 - 0.0018 18.6 4.3 0.0019 18.6 0.0 2.9 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family EamA PF00892.20 CAM43051.1 - 0.0068 16.6 11.6 0.013 15.7 11.6 1.5 1 1 0 1 1 1 1 EamA-like transporter family Tmemb_18A PF09771.9 CAM43051.1 - 0.051 14.0 1.4 0.065 13.6 0.7 1.5 1 1 1 2 2 2 0 Transmembrane protein 188 NAD_binding_1 PF00175.21 CAM43052.1 - 1.4e-18 67.5 0.0 3.1e-16 60.0 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CAM43052.1 - 2.4e-12 47.0 0.0 3.9e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CAM43052.1 - 0.00024 21.2 0.0 0.00044 20.4 0.0 1.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Nsp1_C PF05064.13 CAM43053.1 - 1.9e-06 27.7 0.2 3e-06 27.0 0.2 1.3 1 0 0 1 1 1 1 Nsp1-like C-terminal region Spc7 PF08317.11 CAM43053.1 - 0.026 13.4 3.3 0.036 12.9 3.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein PIN_8 PF18476.1 CAM43053.1 - 0.26 11.1 1.0 0.37 10.6 1.0 1.1 1 0 0 1 1 1 0 PIN like domain CENP-F_leu_zip PF10473.9 CAM43053.1 - 0.3 11.1 1.2 4.8 7.2 0.0 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MGTL PF17059.5 CAM43054.1 - 1.9 8.4 4.9 1.4 8.8 0.3 2.7 2 0 0 2 2 2 0 MgtA leader peptide MIP PF00230.20 CAM43055.1 - 7.4e-31 107.6 17.7 9.3e-31 107.3 17.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF4271 PF14093.6 CAM43055.1 - 0.088 12.7 0.3 0.088 12.7 0.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4271) CitMHS PF03600.16 CAM43055.1 - 0.088 12.0 7.9 0.38 9.9 8.0 2.0 1 1 0 1 1 1 0 Citrate transporter DUF4229 PF14012.6 CAM43055.1 - 0.11 12.6 0.2 0.11 12.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Zeta_toxin PF06414.12 CAM43055.1 - 0.18 11.1 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin UCR_Fe-S_N PF10399.9 CAM43055.1 - 5.5 6.4 7.3 0.72 9.2 2.3 2.2 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal CPP1-like PF11833.8 CAM43055.1 - 6.1 6.4 7.3 2.7 7.6 2.0 2.3 1 1 2 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like MIP PF00230.20 CAM43056.1 - 7.8e-31 107.5 15.8 1.1e-30 107.1 15.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein DNA_pol_lambd_f PF10391.9 CAM43058.1 - 0.001 18.8 0.1 0.0023 17.7 0.1 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda TPR_12 PF13424.6 CAM43060.2 - 1.2e-06 28.7 4.8 1.2e-06 28.7 4.8 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.18 CAM43060.2 - 0.0049 16.9 1.5 0.012 15.6 0.5 2.2 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 CAM43060.2 - 0.12 12.3 11.2 4.4 7.3 0.3 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 CAM43060.2 - 1.6 8.9 8.5 7.7 6.8 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 CAM43060.2 - 7.6 6.9 13.9 11 6.5 0.3 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Methyltr_RsmB-F PF01189.17 CAM43062.1 - 5.4e-30 104.5 0.1 8e-30 104.0 0.1 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F MTS PF05175.14 CAM43062.1 - 0.062 12.9 0.0 0.17 11.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain NUDIX PF00293.28 CAM43063.2 - 0.00064 19.8 0.0 0.0014 18.6 0.0 1.7 1 0 0 1 1 1 1 NUDIX domain MNSV_P7B PF06692.11 CAM43063.2 - 0.1 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Melon necrotic spot virus P7B protein PAP_assoc PF03828.19 CAM43064.1 - 6.5e-09 35.9 0.0 1.2e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CAM43064.1 - 0.0015 18.8 0.0 0.0028 17.9 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 CAM43064.1 - 0.2 11.7 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase ubiquitin PF00240.23 CAM43066.1 - 0.00039 20.1 0.0 0.00055 19.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family DAPG_hydrolase PF18089.1 CAM43066.1 - 0.11 12.1 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 DAPG hydrolase PhiG domain TPR_14 PF13428.6 CAM43067.1 - 1.9e-05 25.1 38.3 1.8 9.6 1.8 10.9 7 4 3 10 10 10 2 Tetratricopeptide repeat TPR_2 PF07719.17 CAM43067.1 - 0.00018 21.4 5.8 0.0047 16.9 1.7 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 CAM43067.1 - 0.0013 19.0 4.0 7.4 7.2 0.1 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat PRP1_N PF06424.12 CAM43067.1 - 0.0043 17.5 0.4 0.0082 16.6 0.4 1.4 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal ANAPC3 PF12895.7 CAM43067.1 - 0.01 16.1 1.0 0.11 12.7 0.3 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 CAM43067.1 - 0.036 13.9 1.5 0.21 11.5 1.5 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Trimer_CC PF08954.11 CAM43067.1 - 0.07 12.7 1.4 7.1 6.3 0.1 3.0 2 0 0 2 2 2 0 Trimerisation motif TPR_12 PF13424.6 CAM43067.1 - 0.11 12.8 12.2 0.22 11.8 1.3 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 CAM43067.1 - 0.3 11.4 3.3 18 5.9 1.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 CAM43067.1 - 0.81 9.9 9.6 2.9 8.1 1.3 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 CAM43067.1 - 3.4 7.4 6.0 35 4.2 3.1 2.8 2 0 0 2 2 2 0 TPR repeat TPR_4 PF07721.14 CAM43067.1 - 4.4 8.2 12.2 6.7 7.6 0.7 4.6 3 1 1 4 4 3 0 Tetratricopeptide repeat cNMP_binding PF00027.29 CAM43071.1 - 1.3e-06 28.3 0.0 0.00027 20.9 0.0 2.9 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain HD PF01966.22 CAM43072.1 - 1e-07 32.2 0.0 2.9e-07 30.7 0.0 1.9 1 0 0 1 1 1 1 HD domain A_deaminase PF00962.22 CAM43073.1 - 4.1e-92 309.0 0.2 3.3e-68 230.4 0.1 2.3 2 0 0 2 2 2 2 Adenosine/AMP deaminase DUF4530 PF15039.6 CAM43073.1 - 0.014 15.6 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) DUF1192 PF06698.11 CAM43073.1 - 0.17 12.0 0.4 0.48 10.5 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Ctr PF04145.15 CAM43074.1 - 0.027 15.1 0.1 0.31 11.6 0.0 2.3 2 0 0 2 2 2 0 Ctr copper transporter family CHCH PF06747.13 CAM43077.1 - 0.0045 17.1 5.2 0.0068 16.5 5.2 1.3 1 0 0 1 1 1 1 CHCH domain Colipase-like PF15083.6 CAM43077.1 - 0.032 14.4 1.2 0.048 13.8 1.2 1.3 1 0 0 1 1 1 0 Colipase-like MTCP1 PF08991.10 CAM43077.1 - 0.044 14.0 2.0 0.044 14.0 2.0 1.5 2 0 0 2 2 2 0 Mature-T-Cell Proliferation I type Sod_Fe_C PF02777.18 CAM43081.1 - 1.8e-26 92.2 1.4 2.5e-26 91.8 1.4 1.1 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_C PF02777.18 CAM43082.1 - 2.3e-31 108.0 0.6 2.3e-31 108.0 0.6 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CAM43082.1 - 9.3e-20 70.9 0.4 2.5e-19 69.5 0.4 1.8 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Cys_Met_Meta_PP PF01053.20 CAM43083.1 - 8.4e-87 291.2 0.0 9.7e-87 291.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SpoU_methylase PF00588.19 CAM43084.2 - 5.2e-27 94.8 0.5 3e-23 82.6 0.0 4.3 5 0 0 5 5 5 2 SpoU rRNA Methylase family Aa_trans PF01490.18 CAM43085.1 - 2.6e-51 174.6 28.7 3.2e-51 174.3 28.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CAM43085.1 - 2.6e-10 39.9 12.6 6.6e-10 38.6 12.5 1.8 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family AA_permease_2 PF13520.6 CAM43085.1 - 0.00018 20.5 21.1 0.00018 20.5 21.1 2.2 1 1 1 2 2 2 1 Amino acid permease NAD_binding_2 PF03446.15 CAM43086.2 - 0.18 11.9 1.7 0.25 11.5 0.1 2.0 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase VASt PF16016.5 CAM43087.1 - 3.7e-08 33.9 0.0 6.5e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain Ribosomal_L27e PF01777.18 CAM43088.2 - 1.1e-10 41.6 0.4 2.1e-10 40.8 0.4 1.4 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 CAM43088.2 - 1e-05 25.3 1.2 1.4e-05 24.9 0.3 1.7 2 0 0 2 2 2 1 KOW motif APC1_C PF18122.1 CAM43089.2 - 0.027 14.4 0.3 0.1 12.6 0.1 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex sub unit 1 C-terminal domain Ribosomal_L27e PF01777.18 CAM43090.1 - 1.8e-25 89.1 1.6 2.6e-25 88.6 1.6 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 CAM43090.1 - 2.4e-05 24.1 1.2 3e-05 23.8 0.3 1.7 2 0 0 2 2 2 1 KOW motif Sybindin PF04099.12 CAM43091.1 - 6.3e-22 78.0 0.0 7.3e-22 77.8 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 CAM43091.1 - 9.1e-08 32.3 0.0 9.2e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Longin PF13774.6 CAM43091.1 - 0.084 12.9 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Regulated-SNARE-like domain Rhodanese PF00581.20 CAM43093.1 - 5.3e-08 33.3 0.0 7.5e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Sec7_N PF12783.7 CAM43094.2 - 8.3e-20 71.3 0.8 1.9e-19 70.1 0.8 1.6 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Sec7 PF01369.20 CAM43094.2 - 3.1e-19 69.4 0.0 4.6e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain RFXA_RFXANK_bdg PF15289.6 CAM43095.2 - 0.044 14.1 0.1 0.13 12.6 0.1 1.8 1 0 0 1 1 1 0 Regulatory factor X-associated C-terminal binding domain GPAT_N PF14829.6 CAM43095.2 - 0.13 12.3 0.1 0.31 11.1 0.1 1.6 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal RNase_T PF00929.24 CAM43098.1 - 6.4e-17 62.6 0.1 5.3e-10 40.1 0.0 2.8 2 1 0 2 2 2 2 Exonuclease DUF5051 PF16473.5 CAM43098.1 - 0.046 13.7 0.5 2.4 8.1 0.8 2.5 2 1 0 2 2 2 0 3' exoribonuclease, RNase T-like DNA_pol_A_exo1 PF01612.20 CAM43098.1 - 0.081 12.6 0.1 0.59 9.8 0.0 2.0 2 0 0 2 2 2 0 3'-5' exonuclease RRM_1 PF00076.22 CAM43100.2 - 2.5e-21 75.2 0.1 3.7e-07 29.9 0.0 3.7 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 CAM43100.2 - 0.029 14.2 0.1 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain RPN7 PF10602.9 CAM43101.1 - 7.6e-48 162.5 0.7 1.7e-47 161.4 0.1 1.8 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 CAM43101.1 - 1.5e-15 57.5 0.2 5.1e-15 55.9 0.0 2.0 3 0 0 3 3 3 1 PCI domain IFT46_B_C PF12317.8 CAM43101.1 - 0.0091 15.8 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal DUF3656 PF12392.8 CAM43102.2 - 0.25 12.0 0.9 0.55 10.9 0.0 2.0 2 0 0 2 2 2 0 Collagenase Prefoldin PF02996.17 CAM43103.1 - 4.8e-11 42.6 0.9 8e-11 41.9 0.1 1.8 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_3 PF13758.6 CAM43103.1 - 7.5e-06 25.9 3.2 0.00043 20.3 0.1 2.3 2 0 0 2 2 2 2 Prefoldin subunit CCDC106 PF15794.5 CAM43103.1 - 0.042 13.6 1.5 0.12 12.0 1.5 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Chibby PF14645.6 CAM43103.1 - 0.097 13.1 0.1 0.18 12.2 0.1 1.5 1 0 0 1 1 1 0 Chibby family Cep57_CLD_2 PF14197.6 CAM43103.1 - 1.1 9.4 11.4 0.21 11.7 2.1 2.6 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 TPR_2 PF07719.17 CAM43104.1 - 3.5e-10 39.2 23.8 0.0068 16.4 0.5 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 CAM43104.1 - 1.1e-07 31.3 21.7 0.077 12.8 0.4 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 CAM43104.1 - 1.4e-07 32.1 5.0 3.5e-06 27.5 0.6 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 CAM43104.1 - 1.2e-06 28.9 16.8 1.2e-05 25.7 0.9 5.0 4 1 0 4 4 4 2 Tetratricopeptide repeat CS PF04969.16 CAM43104.1 - 5.4e-05 24.1 0.3 0.00013 22.9 0.1 1.8 2 0 0 2 2 1 1 CS domain Fis1_TPR_C PF14853.6 CAM43104.1 - 0.0013 18.7 7.9 0.45 10.6 0.1 4.2 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 CAM43104.1 - 0.027 14.7 12.1 1.9 8.8 0.9 3.8 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 CAM43104.1 - 0.031 15.1 32.5 0.12 13.2 0.1 7.3 5 3 2 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 CAM43104.1 - 0.042 14.1 9.5 8 7.0 0.1 4.5 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 CAM43104.1 - 0.092 12.7 11.5 0.53 10.2 0.3 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat XRN_M PF17846.1 CAM43104.1 - 0.12 11.3 0.8 0.23 10.4 0.8 1.4 1 0 0 1 1 1 0 Xrn1 helical domain TPR_12 PF13424.6 CAM43104.1 - 0.18 12.1 0.1 0.18 12.1 0.1 6.3 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 CAM43104.1 - 5.2 7.3 20.8 3.9 7.7 0.2 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat FYVE PF01363.21 CAM43105.2 - 0.0052 16.9 10.6 0.012 15.7 10.6 1.6 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.21 CAM43105.2 - 0.27 11.5 5.9 0.71 10.2 5.9 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain CTP_transf_1 PF01148.20 CAM43106.1 - 7.9e-32 111.1 1.2 1.5e-30 106.8 0.4 3.2 3 1 0 3 3 3 2 Cytidylyltransferase family COX4 PF02936.14 CAM43106.1 - 0.011 15.8 0.1 0.054 13.5 0.0 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV DUF778 PF05608.12 CAM43107.2 - 3.3e-74 249.3 0.0 6.7e-74 248.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF778) SNAP PF14938.6 CAM43109.1 - 9.4e-53 179.5 16.4 1.1e-52 179.3 16.4 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_14 PF13428.6 CAM43109.1 - 4.8e-06 26.9 7.4 2.5 9.2 0.0 5.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CAM43109.1 - 0.00086 19.5 7.1 1.5 9.2 0.5 4.2 1 1 3 5 5 5 4 Tetratricopeptide repeat Foie-gras_1 PF11817.8 CAM43109.1 - 0.0013 18.4 2.0 0.0035 17.0 2.0 1.7 1 1 0 1 1 1 1 Foie gras liver health family 1 Alkyl_sulf_dimr PF14863.6 CAM43109.1 - 0.0027 18.2 5.7 1 9.8 0.1 2.8 1 1 1 2 2 2 2 Alkyl sulfatase dimerisation TPR_MalT PF17874.1 CAM43109.1 - 0.0029 17.0 4.1 0.004 16.6 4.1 1.3 1 0 0 1 1 1 1 MalT-like TPR region TPR_19 PF14559.6 CAM43109.1 - 0.0042 17.6 7.9 0.35 11.4 2.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF4363 PF14276.6 CAM43109.1 - 0.04 14.0 0.1 0.15 12.1 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) ANAPC3 PF12895.7 CAM43109.1 - 0.043 14.1 3.4 0.2 11.9 1.0 2.9 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF1024 PF06260.12 CAM43109.1 - 0.16 12.3 1.5 13 6.2 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1024) TPR_10 PF13374.6 CAM43109.1 - 0.28 11.1 2.4 24 5.0 0.0 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CAM43109.1 - 0.95 9.7 15.6 54 4.3 0.0 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat AvrM_N PF18247.1 CAM43109.1 - 1.2 9.1 6.6 26 4.9 0.1 3.9 1 1 2 3 3 3 0 Flax-rust effector AvrM N-terminal domain TPR_6 PF13174.6 CAM43109.1 - 1.7 9.4 10.1 0.95 10.2 0.2 4.3 5 0 0 5 5 3 0 Tetratricopeptide repeat UCH PF00443.29 CAM43111.2 - 1.7e-49 168.6 0.0 2.6e-49 168.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CAM43111.2 - 9.7e-13 48.4 4.1 5.6e-08 32.7 0.0 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase FG-GAP PF01839.23 CAM43112.1 - 0.0024 18.0 0.3 0.0058 16.7 0.3 1.6 1 0 0 1 1 1 1 FG-GAP repeat VCBS PF13517.6 CAM43112.1 - 0.018 15.6 0.0 0.08 13.5 0.1 2.1 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TTL PF03133.15 CAM43113.1 - 5.1e-61 206.4 0.0 3.3e-45 154.5 0.0 2.1 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CAM43113.1 - 2e-07 30.6 0.0 0.001 18.4 0.0 2.3 2 0 0 2 2 2 2 YheC/D like ATP-grasp DUF1738 PF08401.11 CAM43114.1 - 0.00022 21.3 0.0 0.64 10.1 0.0 3.4 3 0 0 3 3 3 3 Domain of unknown function (DUF1738) NDK PF00334.19 CAM43115.1 - 1e-56 190.7 0.0 1.5e-56 190.2 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase DUF4210 PF13915.6 CAM43115.1 - 0.11 13.1 1.8 1.7 9.3 1.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4210) NDK PF00334.19 CAM43116.1 - 3e-57 192.4 0.0 3.4e-57 192.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.18 CAM43116.1 - 0.1 13.2 0.0 0.16 12.5 0.0 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ MCM PF00493.23 CAM43117.1 - 6.3e-98 326.3 0.0 8.9e-98 325.8 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CAM43117.1 - 1.8e-26 92.5 1.2 3.7e-26 91.4 1.2 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CAM43117.1 - 1.8e-21 76.3 0.1 4.5e-21 75.1 0.1 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CAM43117.1 - 1.1e-07 32.3 0.0 2.7e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CAM43117.1 - 1.2e-06 28.1 0.0 0.00015 21.2 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CAM43117.1 - 4.8e-06 26.6 0.0 1.8e-05 24.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 CAM43117.1 - 0.0015 18.3 0.6 0.0041 16.9 0.6 1.8 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 CAM43117.1 - 0.018 14.9 0.0 0.054 13.4 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HisKA PF00512.25 CAM43117.1 - 0.055 13.5 0.1 2.5 8.2 0.0 2.6 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain AAA PF00004.29 CAM43117.1 - 0.093 13.2 0.1 0.47 10.9 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CAM43117.1 - 0.1 12.3 0.0 0.58 9.8 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain TBCA PF02970.16 CAM43118.1 - 6.7e-18 64.8 2.0 9.1e-18 64.4 2.0 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A Spc7 PF08317.11 CAM43118.1 - 0.0012 17.8 0.9 0.0014 17.5 0.9 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 CAM43118.1 - 0.011 16.4 4.1 0.014 16.0 4.1 1.2 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CHASE3 PF05227.13 CAM43118.1 - 0.017 15.0 2.2 0.025 14.5 2.2 1.2 1 0 0 1 1 1 0 CHASE3 domain DREV PF05219.12 CAM43118.1 - 0.018 14.1 0.1 0.022 13.8 0.1 1.0 1 0 0 1 1 1 0 DREV methyltransferase Med9 PF07544.13 CAM43118.1 - 0.037 14.1 0.7 0.058 13.5 0.7 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 FapA PF03961.13 CAM43118.1 - 0.05 12.2 0.8 0.056 12.0 0.8 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Herpes_U30 PF04523.13 CAM43118.1 - 0.054 11.4 0.4 0.064 11.1 0.4 1.0 1 0 0 1 1 1 0 Herpes virus tegument protein U30 VGPC1_C PF16799.5 CAM43118.1 - 0.063 13.3 1.5 0.082 12.9 0.6 1.7 2 0 0 2 2 2 0 C-terminal membrane-localisation domain of ion-channel, VCN1 Phosducin PF02114.16 CAM43119.1 - 8.4e-11 41.3 0.1 9.4e-11 41.1 0.1 1.0 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 CAM43119.1 - 7.5e-08 32.3 0.0 1.1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 CAM43119.1 - 0.002 18.0 0.0 0.0033 17.3 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein MnmE_helical PF12631.7 CAM43119.1 - 0.06 13.5 0.1 0.06 13.5 0.1 1.1 1 0 0 1 1 1 0 MnmE helical domain Thioredoxin_3 PF13192.6 CAM43119.1 - 0.09 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain zf-C2H2_aberr PF17017.5 CAM43121.1 - 0.054 13.6 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Aberrant zinc-finger Rab5ip PF07019.12 CAM43122.1 - 2.5e-18 66.4 8.7 2.9e-18 66.2 8.7 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF21 PF01595.20 CAM43124.1 - 6e-37 127.0 3.4 8.8e-37 126.5 3.4 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain L_HMGIC_fpl PF10242.9 CAM43124.1 - 1.8 8.8 5.9 0.41 10.8 0.4 2.2 2 0 0 2 2 2 0 Lipoma HMGIC fusion partner-like protein LRR_4 PF12799.7 CAM43125.2 - 1.9e-16 59.9 15.6 1.8e-07 31.3 0.9 3.8 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) AMPK1_CBM PF16561.5 CAM43125.2 - 1.4e-13 50.8 0.0 2.8e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase LRR_8 PF13855.6 CAM43125.2 - 4.1e-12 45.7 2.9 0.0018 18.0 0.3 3.4 3 0 0 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 CAM43125.2 - 3.4e-10 39.7 0.0 1.4e-06 28.0 0.0 2.4 1 1 1 2 2 2 2 Leucine-rich repeat SCAB-Ig PF16709.5 CAM43125.2 - 7.5e-09 35.5 0.0 0.11 12.6 0.0 4.3 4 0 0 4 4 4 2 Ig domain of plant-specific actin-binding protein LRR_6 PF13516.6 CAM43125.2 - 5.3e-05 23.0 7.6 12 6.3 0.5 5.0 4 0 0 4 4 4 3 Leucine Rich repeat LRR_1 PF00560.33 CAM43125.2 - 0.007 16.8 3.7 32 5.6 0.0 5.2 4 1 0 4 4 4 0 Leucine Rich Repeat CBM_48 PF02922.18 CAM43125.2 - 0.065 13.6 0.0 0.59 10.5 0.0 2.5 3 0 0 3 3 3 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) MMR_HSR1 PF01926.23 CAM43126.1 - 9.8e-14 51.4 0.0 2.1e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CAM43126.1 - 9e-07 28.9 0.0 6.1e-05 23.0 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 CAM43126.1 - 0.003 17.1 0.0 0.25 10.9 0.0 2.7 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 CAM43126.1 - 0.053 14.0 0.0 0.15 12.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 CAM43126.1 - 0.056 13.8 0.0 0.19 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain DnaJ PF00226.31 CAM43127.1 - 5.1e-21 74.6 0.0 9.5e-21 73.7 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain DUF4407 PF14362.6 CAM43127.1 - 0.56 9.5 2.4 0.87 8.9 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Metallophos PF00149.28 CAM43128.1 - 1.6e-36 126.7 0.1 2.2e-36 126.3 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CAM43128.1 - 0.022 15.2 0.1 0.048 14.1 0.1 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Roc PF08477.13 CAM43129.1 - 9.8e-15 54.8 0.0 2.2e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CAM43129.1 - 6.2e-12 45.4 0.1 1.4e-11 44.3 0.1 1.5 1 1 0 1 1 1 1 Ras family COR PF16095.5 CAM43129.1 - 4e-08 33.3 0.2 0.0089 15.9 0.1 2.3 2 0 0 2 2 2 2 C-terminal of Roc, COR, domain Gtr1_RagA PF04670.12 CAM43129.1 - 6.4e-05 22.4 0.0 0.0001 21.7 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region IBR PF01485.21 CAM43129.1 - 0.00039 20.6 0.1 0.00095 19.3 0.1 1.6 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain YdjO PF14169.6 CAM43129.1 - 0.062 13.0 0.4 0.13 12.0 0.4 1.5 1 0 0 1 1 1 0 Cold-inducible protein YdjO Zn_Tnp_IS1 PF03811.13 CAM43129.1 - 0.069 12.9 0.3 0.29 10.9 0.2 2.1 2 0 0 2 2 2 0 InsA N-terminal domain zf-MIZ PF02891.20 CAM43132.1 - 1.7e-10 40.5 6.5 3.4e-10 39.5 6.5 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 CAM43132.1 - 9e-07 28.6 1.7 1.8e-06 27.6 1.7 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DZR PF12773.7 CAM43132.1 - 0.066 13.3 0.2 0.066 13.3 0.2 2.3 2 0 0 2 2 2 0 Double zinc ribbon zf-NADH-PPase PF09297.11 CAM43132.1 - 0.83 9.4 8.6 0.078 12.6 3.3 2.1 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Zn-ribbon_8 PF09723.10 CAM43132.1 - 2.5 8.3 5.8 2.3 8.4 0.5 2.7 2 0 0 2 2 2 0 Zinc ribbon domain ABC_tran PF00005.27 CAM43133.1 - 7.1e-35 120.5 0.0 2.1e-34 119.0 0.0 1.8 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 CAM43133.1 - 3.3e-32 112.2 6.7 4.3e-32 111.8 6.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 CAM43133.1 - 5e-06 26.1 0.8 0.00062 19.3 0.8 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CAM43133.1 - 0.00057 20.3 0.0 0.0014 19.1 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 CAM43133.1 - 0.0043 16.8 1.7 0.014 15.1 0.2 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 CAM43133.1 - 0.0071 16.6 0.1 0.11 12.8 0.1 2.4 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CAM43133.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 CAM43133.1 - 0.034 14.6 0.4 0.14 12.6 0.2 1.9 1 1 0 2 2 2 0 AAA domain AAA_21 PF13304.6 CAM43133.1 - 0.041 13.7 0.0 0.073 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Cytidylate_kin PF02224.18 CAM43133.1 - 0.061 13.0 0.0 2.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase AAA PF00004.29 CAM43133.1 - 0.075 13.5 0.1 12 6.3 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CAM43133.1 - 0.089 12.9 0.0 0.35 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CAM43133.1 - 0.12 12.5 0.0 0.43 10.7 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_7 PF12775.7 CAM43133.1 - 0.12 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region FSH1 PF03959.13 CAM43135.1 - 1.9e-28 99.6 0.0 2.8e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) MMR_HSR1_C PF08438.10 CAM43135.1 - 1.4e-23 83.6 0.0 4.5e-23 82.0 0.0 1.9 2 0 0 2 2 2 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 CAM43135.1 - 3.2e-15 56.2 0.0 1.1e-14 54.5 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RWD PF05773.22 CAM43135.1 - 0.00055 20.2 0.0 0.0011 19.2 0.0 1.5 1 0 0 1 1 1 1 RWD domain FeoB_N PF02421.18 CAM43135.1 - 0.00094 18.7 0.0 0.0042 16.6 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Hydrolase_4 PF12146.8 CAM43135.1 - 0.02 14.2 0.1 0.44 9.8 0.0 2.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Ribosomal_L3 PF00297.22 CAM43136.1 - 1.4e-55 188.8 0.4 1.5e-55 188.7 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Ribosomal_L3 PF00297.22 CAM43137.1 - 5.1e-40 137.6 0.2 6.1e-40 137.3 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 Aldedh PF00171.22 CAM43138.1 - 3e-15 55.7 12.9 7.1e-12 44.6 3.3 3.0 3 1 0 3 3 3 2 Aldehyde dehydrogenase family YadA_anchor PF03895.15 CAM43138.1 - 0.13 12.4 0.4 0.46 10.6 0.4 1.9 1 0 0 1 1 1 0 YadA-like membrane anchor domain DUF1542 PF07564.11 CAM43138.1 - 3.8 7.7 6.0 3 8.0 1.0 2.7 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1542) IQ PF00612.27 CAM43139.1 - 3.3e-15 54.4 102.1 2e-05 24.0 3.6 12.9 12 0 0 12 12 12 8 IQ calmodulin-binding motif TPR_10 PF13374.6 CAM43139.1 - 0.031 14.2 0.0 0.031 14.2 0.0 7.5 8 0 0 8 8 8 0 Tetratricopeptide repeat CCDC-167 PF15188.6 CAM43139.1 - 0.25 11.7 4.2 34 4.9 0.3 5.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 SOCS PF12610.8 CAM43139.1 - 0.62 10.5 15.1 4.2 7.8 0.4 6.2 4 0 0 4 4 4 0 Suppressor of cytokine signalling YhfZ_C PF14503.6 CAM43139.1 - 2.2 7.8 7.3 45 3.5 0.2 3.4 3 0 0 3 3 3 0 YhfZ C-terminal domain LRR_6 PF13516.6 CAM43140.1 - 2.2e-07 30.4 5.7 0.11 12.6 0.1 4.7 5 0 0 5 5 5 3 Leucine Rich repeat LRR_4 PF12799.7 CAM43140.1 - 6.7e-05 23.2 1.4 0.0035 17.7 0.5 3.1 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) ANAPC_CDC26 PF10471.9 CAM43140.1 - 0.033 15.0 1.2 0.033 15.0 1.2 2.9 3 1 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 LRR_8 PF13855.6 CAM43140.1 - 0.085 12.6 0.2 1.1 9.1 0.2 2.6 3 0 0 3 3 3 0 Leucine rich repeat L51_S25_CI-B8 PF05047.16 CAM43141.1 - 0.0084 16.0 0.1 0.013 15.4 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Choline_kin_N PF04428.14 CAM43142.1 - 0.19 11.4 0.0 0.43 10.3 0.0 1.6 1 0 0 1 1 1 0 Choline kinase N terminus COG5 PF10392.9 CAM43143.1 - 7.3e-15 55.3 17.9 9.4e-13 48.5 2.0 4.2 3 1 1 4 4 4 2 Golgi transport complex subunit 5 DUF1664 PF07889.12 CAM43143.1 - 0.022 14.8 1.3 0.058 13.4 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Tombus_P19 PF03220.13 CAM43143.1 - 0.16 11.7 0.3 0.52 10.0 0.1 1.9 2 0 0 2 2 2 0 Tombusvirus P19 core protein COG2 PF06148.11 CAM43143.1 - 1.9 8.5 6.1 3.1 7.9 2.5 3.2 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Sigma70_ner PF04546.13 CAM43144.2 - 0.65 9.9 5.2 0.98 9.3 0.7 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region Roc PF08477.13 CAM43145.1 - 8e-08 32.5 0.2 6.9e-07 29.5 0.2 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAM43145.1 - 1.7e-05 24.3 0.3 0.0013 18.2 0.3 2.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CAM43145.1 - 0.00031 20.4 0.0 0.0011 18.6 0.0 1.9 2 1 0 2 2 2 1 Ras family G-alpha PF00503.20 CAM43145.1 - 0.0005 19.3 0.1 0.8 8.8 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 CAM43145.1 - 0.0031 17.6 0.0 0.0054 16.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CAM43145.1 - 0.0085 16.2 0.1 0.025 14.7 0.1 1.7 1 1 1 2 2 2 1 Dynamin family PduV-EutP PF10662.9 CAM43145.1 - 0.011 15.5 0.0 0.03 14.1 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 CAM43145.1 - 0.013 15.1 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CAM43145.1 - 0.049 13.1 0.1 0.099 12.1 0.1 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 CAM43145.1 - 0.09 13.3 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 CAM43145.1 - 0.11 11.5 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein CLP1_P PF16575.5 CAM43146.1 - 0.046 13.5 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop FAA_hydro_N_2 PF18288.1 CAM43146.1 - 0.066 13.6 1.0 0.12 12.8 0.1 1.9 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 AAA_16 PF13191.6 CAM43147.1 - 5.2e-07 30.2 0.0 1e-06 29.3 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain Roc PF08477.13 CAM43147.1 - 5.4e-06 26.6 0.0 2.5e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 CAM43147.1 - 6.4e-05 22.6 0.0 0.26 10.8 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 CAM43147.1 - 0.0003 21.1 0.4 0.013 15.7 0.1 2.7 2 2 0 2 2 2 1 AAA domain NACHT PF05729.12 CAM43147.1 - 0.0006 19.8 0.0 0.0025 17.8 0.0 1.9 2 0 0 2 2 2 1 NACHT domain FtsK_SpoIIIE PF01580.18 CAM43147.1 - 0.0016 17.9 0.0 0.0032 16.9 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family cobW PF02492.19 CAM43147.1 - 0.0026 17.4 0.1 0.024 14.2 0.1 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 CAM43147.1 - 0.0029 18.0 0.0 0.0053 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CAM43147.1 - 0.0032 17.6 1.2 0.041 14.0 0.1 2.6 1 1 0 2 2 2 1 AAA domain G-alpha PF00503.20 CAM43147.1 - 0.0033 16.6 0.0 0.054 12.6 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit NB-ARC PF00931.22 CAM43147.1 - 0.0048 16.1 0.0 0.0087 15.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain ATP_bind_1 PF03029.17 CAM43147.1 - 0.0049 16.7 0.3 0.21 11.4 0.2 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 CAM43147.1 - 0.0055 16.4 0.1 0.01 15.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CAM43147.1 - 0.016 15.0 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 CAM43147.1 - 0.017 15.1 0.1 0.036 14.0 0.1 1.5 1 0 0 1 1 1 0 NTPase ABC_tran PF00005.27 CAM43147.1 - 0.017 15.6 0.0 0.042 14.4 0.0 1.6 1 1 0 1 1 1 0 ABC transporter MCM PF00493.23 CAM43147.1 - 0.018 14.2 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain Arf PF00025.21 CAM43147.1 - 0.018 14.5 0.0 0.24 10.9 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_24 PF13479.6 CAM43147.1 - 0.021 14.6 0.2 0.2 11.3 0.0 2.6 2 1 1 3 3 3 0 AAA domain T2SSE PF00437.20 CAM43147.1 - 0.029 13.4 0.0 0.06 12.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 CAM43147.1 - 0.032 14.1 0.0 3 7.7 0.0 2.6 2 1 1 3 3 3 0 RsgA GTPase AAA_28 PF13521.6 CAM43147.1 - 0.039 14.2 0.0 0.11 12.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.12 CAM43147.1 - 0.045 13.0 0.0 0.091 12.0 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 CAM43147.1 - 0.055 13.2 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CAM43147.1 - 0.066 13.3 0.2 0.17 12.0 0.2 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase DAP3 PF10236.9 CAM43147.1 - 0.067 12.3 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA PF00004.29 CAM43147.1 - 0.069 13.6 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 CAM43147.1 - 0.089 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Septin Mg_chelatase PF01078.21 CAM43147.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CAM43147.1 - 0.14 12.7 0.0 0.38 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 CAM43147.1 - 0.15 11.5 0.0 0.32 10.4 0.0 1.5 2 0 0 2 2 1 0 Poxvirus A32 protein SRPRB PF09439.10 CAM43147.1 - 0.17 11.3 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Pkinase PF00069.25 CAM43149.2 - 3.4e-76 256.1 0.0 4.6e-76 255.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM43149.2 - 6.7e-36 123.9 0.0 4.3e-35 121.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 CAM43149.2 - 0.0023 17.5 0.0 0.0045 16.6 0.0 1.4 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 CAM43149.2 - 0.016 14.9 0.0 6.5 6.3 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 CAM43149.2 - 0.029 13.3 0.1 0.049 12.6 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 CAM43149.2 - 0.057 12.7 0.0 0.14 11.4 0.0 1.6 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 CAM43149.2 - 0.058 13.3 0.5 1.2 9.0 0.1 2.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CAM43149.2 - 0.065 12.3 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Glucosamine_iso PF01182.20 CAM43150.1 - 5.7e-21 75.4 0.0 7.1e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Phytoreo_S7 PF07236.11 CAM43150.1 - 0.047 12.0 0.1 0.058 11.8 0.1 1.1 1 0 0 1 1 1 0 Phytoreovirus S7 protein Cpn60_TCP1 PF00118.24 CAM43151.1 - 2.8e-144 481.4 10.8 3.2e-144 481.2 10.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GlcNAc-1_reg PF18440.1 CAM43151.1 - 0.11 12.7 0.4 1.1 9.6 0.0 2.6 3 0 0 3 3 3 0 Putative GlcNAc-1 phosphotransferase regulatory domain DnaJ_C PF01556.18 CAM43154.2 - 2.9e-26 92.3 0.0 3.9e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CAM43154.2 - 3.8e-17 62.2 4.5 6.9e-17 61.3 4.5 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CAM43154.2 - 1.7e-11 44.3 14.0 2.8e-11 43.6 14.0 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CAM43154.2 - 9.9e-07 28.6 7.9 0.004 17.1 1.3 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein Arabinose_Isome PF02610.15 CAM43154.2 - 0.0053 16.0 0.2 0.0077 15.5 0.2 1.1 1 0 0 1 1 1 1 L-arabinose isomerase TackOD1 PF18551.1 CAM43154.2 - 0.043 13.5 4.2 2.4 7.8 0.4 2.5 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 DUF5402 PF17393.2 CAM43154.2 - 0.062 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5402) HypA PF01155.19 CAM43154.2 - 0.11 12.5 9.9 1.1 9.3 1.5 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 CAM43154.2 - 0.2 11.7 10.3 1.5 8.9 10.3 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf-C3HC4_3 PF13920.6 CAM43154.2 - 2.9 7.8 6.8 0.97 9.3 0.9 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) A2L_zn_ribbon PF08792.10 CAM43154.2 - 5.1 6.9 8.5 13 5.6 0.0 3.7 4 0 0 4 4 4 0 A2L zinc ribbon domain Pyr_redox_2 PF07992.14 CAM43155.1 - 6.1e-67 225.9 6.0 6.1e-67 225.9 6.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CAM43155.1 - 4.9e-41 139.4 1.0 1.2e-40 138.2 1.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CAM43155.1 - 9.4e-18 64.6 11.9 1.7e-16 60.6 2.1 3.1 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CAM43155.1 - 1e-12 48.0 10.9 6.4e-11 42.1 0.0 2.9 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CAM43155.1 - 5.6e-10 39.1 1.4 5.6e-10 39.1 1.4 3.6 3 1 1 4 4 4 2 FAD dependent oxidoreductase GIDA PF01134.22 CAM43155.1 - 7e-10 38.5 11.6 1.4e-08 34.3 5.5 2.7 2 1 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 CAM43155.1 - 3.8e-07 30.2 6.2 4.2e-05 23.7 0.8 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CAM43155.1 - 5.2e-06 25.8 3.2 5.2e-06 25.8 3.2 2.9 2 1 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 CAM43155.1 - 3.5e-05 23.2 1.8 0.00034 19.9 0.1 2.5 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 CAM43155.1 - 4.2e-05 22.8 0.6 0.014 14.5 0.0 2.5 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 CAM43155.1 - 7.6e-05 22.1 9.5 0.0038 16.6 0.4 3.3 3 1 1 4 4 4 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 CAM43155.1 - 9.5e-05 21.8 12.9 0.02 14.2 0.6 3.2 2 1 1 3 3 3 3 FAD binding domain HI0933_like PF03486.14 CAM43155.1 - 0.00052 18.8 1.2 0.00052 18.8 1.2 3.8 3 1 1 4 4 4 1 HI0933-like protein 3HCDH_N PF02737.18 CAM43155.1 - 0.0012 18.8 6.4 0.003 17.5 0.5 3.4 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 CAM43155.1 - 0.024 15.1 0.4 0.67 10.5 0.1 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain Lycopene_cycl PF05834.12 CAM43155.1 - 0.028 13.5 0.2 1.2 8.2 0.0 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 CAM43155.1 - 0.82 9.2 5.0 0.36 10.4 0.4 2.5 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.24 CAM43155.1 - 1 8.8 18.0 2.5 7.6 3.0 3.3 2 2 1 3 3 3 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 CAM43155.1 - 6.4 7.3 7.6 2.2 8.8 1.2 2.9 3 1 0 3 3 2 0 Putative NAD(P)-binding Cyclin_N PF00134.23 CAM43156.2 - 1.6e-38 131.3 4.3 9.7e-38 128.8 1.1 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 CAM43156.2 - 1.4e-31 109.0 0.0 3.9e-31 107.6 0.0 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_C_2 PF16899.5 CAM43156.2 - 0.018 15.4 0.0 0.041 14.3 0.0 1.7 1 0 0 1 1 1 0 Cyclin C-terminal domain Na_H_antiporter PF03553.14 CAM43157.1 - 0.083 12.1 0.0 0.094 11.9 0.0 1.0 1 0 0 1 1 1 0 Na+/H+ antiporter family GTA_holin_3TM PF11351.8 CAM43157.1 - 0.62 10.6 5.2 0.67 10.5 0.4 2.0 1 1 1 2 2 2 0 Holin of 3TMs, for gene-transfer release zf-B_box PF00643.24 CAM43159.2 - 2.1e-07 31.0 5.7 5.5e-07 29.6 5.7 1.8 1 0 0 1 1 1 1 B-box zinc finger Lipase_3 PF01764.25 CAM43160.1 - 4.7e-10 39.5 0.0 2.3e-09 37.3 0.0 2.0 2 0 0 2 2 2 1 Lipase (class 3) Hydrolase_4 PF12146.8 CAM43160.1 - 0.04 13.2 0.1 0.1 11.8 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Voltage_CLC PF00654.20 CAM43161.1 - 3.6e-79 266.6 26.7 6.1e-79 265.8 24.6 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 CAM43161.1 - 2e-07 31.3 0.1 0.00018 21.9 0.0 2.6 2 0 0 2 2 2 2 CBS domain Romo1 PF10247.9 CAM43161.1 - 4.2 7.8 9.0 0.35 11.2 0.2 3.4 4 0 0 4 4 4 0 Reactive mitochondrial oxygen species modulator 1 TruD PF01142.18 CAM43162.2 - 5.7e-32 111.1 0.0 3e-28 98.8 0.0 3.2 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) YqgC PF17430.2 CAM43162.2 - 1.7 8.8 7.0 2 8.5 1.0 3.3 3 0 0 3 3 3 0 Uncharacterized YqgC-like zf-MYND PF01753.18 CAM43163.1 - 0.0054 16.8 13.7 0.0054 16.8 13.7 2.3 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.6 CAM43163.1 - 0.0071 16.4 7.0 0.0071 16.4 7.0 2.2 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-C2H2_4 PF13894.6 CAM43163.1 - 3.9 8.6 11.4 18 6.5 11.4 2.3 1 0 0 1 1 1 0 C2H2-type zinc finger zf-HIT PF04438.16 CAM43163.1 - 4.1 7.4 10.7 1 9.3 6.9 2.0 2 0 0 2 2 2 0 HIT zinc finger Abhydrolase_1 PF00561.20 CAM43164.1 - 0.0003 20.5 2.3 0.0006 19.5 0.1 2.3 3 0 0 3 3 3 1 alpha/beta hydrolase fold UPF0564 PF10595.9 CAM43166.1 - 3.4e-08 32.9 10.6 7.1e-07 28.6 0.5 3.5 4 0 0 4 4 4 2 Uncharacterised protein family UPF0564 7TMR-HDED PF07697.11 CAM43166.1 - 3.8 7.6 7.5 2.3 8.3 2.8 2.6 3 0 0 3 3 3 0 7TM-HD extracellular zf-C2HC_2 PF13913.6 CAM43168.1 - 3.4e-20 71.4 15.6 4.9e-09 35.9 0.5 3.8 3 0 0 3 3 3 3 zinc-finger of a C2HC-type zinc_ribbon_2 PF13240.6 CAM43168.1 - 0.00054 19.6 5.8 0.00054 19.6 5.8 3.5 3 0 0 3 3 3 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 CAM43168.1 - 0.011 15.1 3.4 0.011 15.1 3.4 3.4 4 0 0 4 4 4 0 zinc-ribbon domain NOB1_Zn_bind PF08772.11 CAM43168.1 - 0.2 11.9 3.0 0.63 10.2 3.0 1.9 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zf_UBZ PF18439.1 CAM43168.1 - 0.2 11.3 6.1 9.6 5.9 0.0 4.0 3 1 1 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-CHCC PF10276.9 CAM43168.1 - 0.44 10.6 3.4 0.59 10.2 0.1 2.7 3 0 0 3 3 3 0 Zinc-finger domain DZR PF12773.7 CAM43168.1 - 0.75 9.9 16.3 1.5 8.9 10.3 3.6 3 1 0 3 3 3 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 CAM43168.1 - 0.92 10.3 6.0 0.3 11.9 2.2 2.3 3 1 0 3 3 1 0 zinc-ribbon family zf-LYAR PF08790.11 CAM43168.1 - 1 9.3 4.8 17 5.4 0.9 3.1 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-RING_7 PF02591.15 CAM43168.1 - 3 8.1 7.6 42 4.4 0.1 3.9 3 1 1 4 4 4 0 C4-type zinc ribbon domain DUF2318 PF10080.9 CAM43168.1 - 3.1 8.0 7.0 44 4.3 0.1 3.7 4 0 0 4 4 4 0 Predicted membrane protein (DUF2318) RNase_PH PF01138.21 CAM43169.1 - 4.4e-06 27.2 0.0 7.6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CAM43169.1 - 9.1e-05 22.4 0.0 0.00015 21.7 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 RRM_1 PF00076.22 CAM43170.2 - 6.8e-11 41.8 0.0 1.1e-07 31.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF515 PF04415.12 CAM43170.2 - 0.33 9.3 5.6 0.52 8.7 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) JUPITER PF17054.5 CAM43170.2 - 1.7 8.0 6.6 2.7 7.4 6.6 1.2 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter Raf1_N PF18578.1 CAM43171.1 - 0.2 12.2 1.5 0.49 10.9 1.5 1.6 1 0 0 1 1 1 0 Rubisco accumulation factor 1 alpha helical domain TPR_19 PF14559.6 CAM43171.1 - 1 10.0 12.6 2.4 8.7 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat DEAD PF00270.29 CAM43172.1 - 7e-18 65.0 0.0 1.3e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAM43172.1 - 0.0001 22.6 0.0 0.00043 20.6 0.0 2.1 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAM43172.1 - 0.00055 20.0 0.0 0.0009 19.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CAM43172.1 - 0.014 15.6 0.0 10 6.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 CAM43172.1 - 0.031 13.7 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.29 CAM43172.1 - 0.048 14.1 0.1 0.75 10.2 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 CAM43172.1 - 0.09 12.5 0.0 0.67 9.7 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein EspB_PE PF18625.1 CAM43172.1 - 0.41 11.1 5.4 0.25 11.8 2.1 2.3 2 0 0 2 2 2 0 ESX-1 secreted protein B PE domain Torus PF16131.5 CAM43174.2 - 2e-05 25.2 4.0 0.2 12.3 2.2 2.4 2 0 0 2 2 2 2 Torus domain zf-CCCH PF00642.24 CAM43174.2 - 0.00066 19.5 1.5 0.00066 19.5 1.5 2.5 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 CAM43174.2 - 0.0044 17.5 2.8 0.0044 17.5 2.8 2.8 3 0 0 3 3 3 1 RNA-binding, Nab2-type zinc finger Robl_LC7 PF03259.17 CAM43176.1 - 9.9e-09 34.9 0.1 3.8e-08 33.0 0.0 1.8 2 0 0 2 2 2 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 CAM43176.1 - 0.00087 19.2 0.1 0.0032 17.4 0.1 1.9 1 1 0 1 1 1 1 Ragulator complex protein LAMTOR5 Methyltr_RsmB-F PF01189.17 CAM43178.1 - 0.00028 20.6 0.0 0.00052 19.7 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Glu_cyclase_2 PF05096.12 CAM43179.1 - 0.037 13.5 0.1 0.062 12.7 0.1 1.3 1 0 0 1 1 1 0 Glutamine cyclotransferase TMF_TATA_bd PF12325.8 CAM43179.1 - 0.21 11.8 17.6 0.34 11.1 1.2 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding MscS_TM PF12794.7 CAM43179.1 - 1.1 8.0 6.1 1.7 7.4 6.1 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF2205 PF10224.9 CAM43179.1 - 4.9 7.2 9.9 12 6.0 1.1 3.2 3 1 1 4 4 4 0 Short coiled-coil protein Seryl_tRNA_N PF02403.22 CAM43179.1 - 5.3 7.3 9.6 4.1 7.7 0.4 2.9 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Spc24 PF08286.11 CAM43179.1 - 8.4 6.7 10.4 10 6.4 4.2 2.5 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 PH PF00169.29 CAM43181.2 - 0.00032 21.2 0.0 0.00083 19.8 0.0 1.7 1 1 0 1 1 1 1 PH domain PH_6 PF15406.6 CAM43181.2 - 0.19 12.0 0.0 0.41 11.0 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain ECH_2 PF16113.5 CAM43184.1 - 3.2e-88 296.4 0.0 3.7e-88 296.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CAM43184.1 - 1.6e-15 57.1 0.0 2.5e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CAM43185.1 - 3.5e-81 273.3 0.0 3.9e-81 273.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CAM43185.1 - 2e-13 50.2 0.0 3.1e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CAM43186.1 - 1.4e-102 343.7 0.0 1.6e-102 343.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CAM43186.1 - 3e-21 75.9 0.0 2.5e-20 72.8 0.0 1.9 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ABATE PF07336.11 CAM43186.1 - 0.09 13.4 0.3 0.17 12.6 0.3 1.5 1 0 0 1 1 1 0 Putative stress-induced transcription regulator DUF4674 PF15719.5 CAM43189.1 - 0.01 15.9 1.6 0.01 15.9 1.6 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4674) DUF2614 PF11023.8 CAM43189.1 - 0.099 12.7 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 Zinc-ribbon containing domain Rubredoxin_2 PF18073.1 CAM43189.1 - 0.11 12.2 0.3 0.11 12.2 0.3 2.1 2 0 0 2 2 2 0 Rubredoxin metal binding domain BT1 PF03092.16 CAM43190.1 - 1.2e-26 93.1 23.2 1.2e-15 56.8 7.6 2.1 2 0 0 2 2 2 2 BT1 family Herpes_US9 PF06072.11 CAM43190.1 - 1.2 9.1 5.6 1.8 8.5 0.2 3.3 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 DUF3948 PF13134.6 CAM43190.1 - 1.8 8.3 6.3 0.36 10.6 0.8 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3948) TMEM18 PF14770.6 CAM43191.1 - 5e-27 94.2 0.7 6.4e-27 93.9 0.7 1.1 1 0 0 1 1 1 1 Transmembrane protein 18 Spexin PF15171.6 CAM43191.1 - 0.054 13.7 0.5 0.093 12.9 0.5 1.4 1 0 0 1 1 1 0 Neuropeptide secretory protein family, NPQ, spexin TYW3 PF02676.14 CAM43193.1 - 4.5e-48 163.4 0.0 5.1e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase TYW3 AAA_assoc_2 PF16193.5 CAM43194.1 - 0.15 12.4 0.3 10 6.5 0.3 3.4 4 0 0 4 4 4 0 AAA C-terminal domain Tom5 PF10642.9 CAM43195.1 - 0.07 13.2 0.4 3.9 7.6 0.1 2.6 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase SufE PF02657.15 CAM43195.1 - 0.11 12.4 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Fe-S metabolism associated domain GDWWSH PF15667.5 CAM43196.1 - 0.00065 19.2 0.4 0.00085 18.8 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function with motif GDWWSH CKS PF01111.19 CAM43197.1 - 7.9e-37 125.4 0.9 9.6e-37 125.1 0.9 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit TPR_2 PF07719.17 CAM43198.1 - 1.7e-07 30.8 0.7 0.13 12.4 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CAM43198.1 - 7.5e-07 28.7 0.4 0.1 12.4 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CAM43198.1 - 0.00032 20.9 2.1 0.29 11.4 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CAM43198.1 - 0.016 15.4 0.0 1.9 8.9 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 CAM43198.1 - 0.16 11.9 1.1 4.5 7.3 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CAM43198.1 - 0.37 11.5 6.0 26 5.7 0.1 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat SHQ1 PF04925.15 CAM43199.1 - 3.6e-34 117.9 0.0 6.3e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 SHQ1 protein PsbQ PF05757.11 CAM43199.1 - 0.12 12.1 0.7 5.4 6.7 0.1 2.2 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) ANAPC4_WD40 PF12894.7 CAM43200.1 - 9.9e-05 22.6 0.0 1.5 9.2 0.0 3.9 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CAM43200.1 - 0.0029 18.4 2.4 25 5.9 0.0 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat Cornichon PF03311.14 CAM43201.1 - 5.3e-14 52.6 9.5 5.3e-14 52.6 9.5 1.7 1 1 1 2 2 2 1 Cornichon protein Pox_P21 PF05313.12 CAM43201.1 - 0.01 15.4 1.0 0.01 15.4 1.0 2.6 1 1 2 3 3 3 0 Poxvirus P21 membrane protein 7tm_1 PF00001.21 CAM43201.1 - 7.5 5.8 11.2 8.1 5.7 8.7 2.1 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) Cornichon PF03311.14 CAM43202.1 - 1.5e-23 83.4 1.5 1.5e-23 83.4 1.5 1.7 1 1 0 1 1 1 1 Cornichon protein DUF1192 PF06698.11 CAM43203.1 - 0.00041 20.3 0.6 1.4 9.0 0.0 3.6 4 0 0 4 4 4 1 Protein of unknown function (DUF1192) HALZ PF02183.18 CAM43203.1 - 0.00049 20.3 1.6 1.3 9.3 0.2 3.4 3 0 0 3 3 3 1 Homeobox associated leucine zipper Lzipper-MIP1 PF14389.6 CAM43203.1 - 0.0022 18.3 4.7 0.011 16.0 0.1 2.7 2 1 1 3 3 3 1 Leucine-zipper of ternary complex factor MIP1 Shugoshin_N PF07558.11 CAM43203.1 - 0.0048 16.7 2.7 0.0076 16.1 0.4 2.4 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Mod_r PF07200.13 CAM43203.1 - 0.018 15.2 2.8 0.44 10.6 0.4 2.4 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein NEMO PF11577.8 CAM43203.1 - 0.03 14.3 2.0 3.5 7.7 0.2 2.5 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO CorA PF01544.18 CAM43203.1 - 0.065 12.5 5.8 0.77 9.0 2.7 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein LMBR1 PF04791.16 CAM43203.1 - 0.066 12.1 0.2 0.085 11.8 0.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein bZIP_1 PF00170.21 CAM43203.1 - 0.069 13.3 3.4 1.1 9.4 0.3 3.2 3 0 0 3 3 3 0 bZIP transcription factor Cnn_1N PF07989.11 CAM43203.1 - 0.25 11.5 2.6 22 5.3 0.1 2.9 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 ZapB PF06005.12 CAM43203.1 - 0.3 11.5 4.6 0.64 10.5 0.9 2.5 2 1 0 2 2 2 0 Cell division protein ZapB DivIVA PF05103.13 CAM43203.1 - 0.33 11.0 2.0 23 5.1 0.1 3.2 3 0 0 3 3 3 0 DivIVA protein TSC22 PF01166.18 CAM43203.1 - 0.35 11.2 2.8 5.1 7.5 0.2 3.1 3 0 0 3 3 3 0 TSC-22/dip/bun family Wtap PF17098.5 CAM43203.1 - 0.35 10.8 8.8 2.7 7.9 0.2 3.1 2 1 1 3 3 3 0 WTAP/Mum2p family CtIP_N PF10482.9 CAM43203.1 - 1.6 8.8 8.2 6.1 6.9 0.2 3.1 2 1 0 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain bZIP_2 PF07716.15 CAM43203.1 - 1.8 8.7 8.2 5.2 7.2 0.8 3.3 3 0 0 3 3 3 0 Basic region leucine zipper DUF737 PF05300.11 CAM43204.2 - 0.25 11.7 0.1 0.25 11.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF737) Myosin_head PF00063.21 CAM43205.1 - 9.6e-177 589.2 0.1 1.4e-176 588.6 0.1 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) UBA PF00627.31 CAM43205.1 - 4.2e-07 29.8 0.0 0.0083 16.0 0.0 3.1 3 0 0 3 3 3 2 UBA/TS-N domain AAA_16 PF13191.6 CAM43205.1 - 0.0011 19.4 0.3 0.49 10.7 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 CAM43205.1 - 0.0014 18.9 0.0 0.032 14.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_lid_6 PF17866.1 CAM43205.1 - 0.0074 16.5 0.2 0.12 12.5 0.0 3.0 3 0 0 3 3 3 1 AAA lid domain CUE PF02845.16 CAM43205.1 - 0.013 15.2 0.1 1.6 8.5 0.3 3.3 3 0 0 3 3 3 0 CUE domain Mg_chelatase PF01078.21 CAM43205.1 - 0.019 14.3 0.0 0.053 12.9 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Peptidase_M16_C PF05193.21 CAM43205.1 - 0.028 14.4 0.0 0.054 13.5 0.0 1.5 1 0 0 1 1 1 0 Peptidase M16 inactive domain DUF1640 PF07798.11 CAM43205.1 - 0.06 13.4 0.9 0.16 12.0 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) AAA_18 PF13238.6 CAM43205.1 - 0.068 13.7 0.3 12 6.5 0.0 3.0 2 1 0 2 2 2 0 AAA domain Myosin_N PF02736.19 CAM43205.1 - 0.073 12.9 0.1 0.33 10.8 0.1 2.2 3 0 0 3 3 3 0 Myosin N-terminal SH3-like domain Zeta_toxin PF06414.12 CAM43205.1 - 1.1 8.5 4.1 1.1 8.5 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin Peptidase_C54 PF03416.19 CAM43207.1 - 2.2e-43 148.7 0.0 2.8e-43 148.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Ribosomal_L2_C PF03947.18 CAM43208.1 - 5.5e-43 146.2 3.5 1.2e-42 145.1 2.1 2.0 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CAM43208.1 - 4.2e-13 49.1 0.1 1.2e-12 47.6 0.1 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain COPIIcoated_ERV PF07970.12 CAM43209.1 - 1.2e-35 123.3 0.1 1.7e-35 122.9 0.1 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CAM43209.1 - 8.3e-26 90.2 0.7 1.5e-25 89.3 0.7 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) ERCC3_RAD25_C PF16203.5 CAM43210.1 - 1.8e-70 237.0 0.1 3.6e-70 236.0 0.1 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 CAM43210.1 - 1.7e-19 70.3 0.1 3.8e-19 69.1 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAM43210.1 - 4.7e-13 49.5 0.0 8.7e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CAM43210.1 - 1.1e-10 41.9 0.0 2.5e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 CAM43210.1 - 5.1e-05 22.1 0.0 0.00012 21.0 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain HECT PF00632.25 CAM43211.2 - 5.4e-37 127.9 0.1 1.3e-36 126.7 0.1 1.6 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 CAM43211.2 - 2.1e-27 95.6 0.0 2.9e-07 30.6 0.0 4.8 5 0 0 5 5 5 4 SPRY domain ZZ PF00569.17 CAM43211.2 - 0.0057 16.4 12.0 0.015 15.1 12.0 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type zf-UBR PF02207.20 CAM43211.2 - 0.0065 16.6 5.4 0.025 14.7 5.4 2.0 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) PIN_4 PF13638.6 CAM43212.1 - 0.0062 16.8 0.0 0.035 14.4 0.0 2.3 1 1 0 1 1 1 1 PIN domain PG_binding_1 PF01471.18 CAM43214.1 - 0.012 15.9 0.4 0.084 13.1 0.0 2.5 3 0 0 3 3 3 0 Putative peptidoglycan binding domain CARD_2 PF16739.5 CAM43214.1 - 0.023 14.7 0.0 0.089 12.8 0.0 1.9 2 0 0 2 2 2 0 Caspase recruitment domain cNMP_binding PF00027.29 CAM43215.1 - 3.7e-21 75.0 0.0 1.9e-08 34.3 0.0 4.0 3 1 0 3 3 3 3 Cyclic nucleotide-binding domain 7TM_GPCR_Sri PF10327.9 CAM43215.1 - 0.0098 15.1 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri GCM PF03615.15 CAM43215.1 - 0.086 12.7 0.1 0.23 11.4 0.1 1.7 1 0 0 1 1 1 0 GCM motif protein Gar1 PF04410.14 CAM43216.1 - 1.4e-24 86.6 0.0 2.1e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Glycos_transf_2 PF00535.26 CAM43217.2 - 9.1e-06 25.6 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 PK PF00224.21 CAM43218.1 - 1.9e-140 467.7 1.3 2.4e-140 467.4 1.3 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 CAM43218.1 - 1.3e-27 96.3 0.2 1.3e-27 96.3 0.2 2.3 3 0 0 3 3 3 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 CAM43218.1 - 4.4e-05 22.7 0.6 0.00014 21.1 0.7 1.8 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Peripla_BP_1 PF00532.21 CAM43218.1 - 0.034 13.6 0.0 0.13 11.6 0.0 2.0 2 0 0 2 2 2 0 Periplasmic binding proteins and sugar binding domain of LacI family DUF3479 PF11965.8 CAM43218.1 - 0.16 12.0 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3479) Peptidase_A17 PF05380.13 CAM43219.2 - 0.0012 18.9 0.1 0.021 14.8 0.0 2.2 1 1 1 2 2 2 1 Pao retrotransposon peptidase RVT_1 PF00078.27 CAM43219.2 - 0.0016 18.0 0.0 0.004 16.7 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) PK PF00224.21 CAM43221.1 - 1.2e-139 465.1 1.4 1.5e-139 464.8 1.4 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 CAM43221.1 - 4.1e-21 75.4 1.8 7.4e-21 74.6 0.1 2.3 3 0 0 3 3 3 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 CAM43221.1 - 4e-05 22.9 0.6 0.00013 21.2 0.7 1.8 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Peripla_BP_1 PF00532.21 CAM43221.1 - 0.035 13.5 0.0 0.14 11.5 0.0 1.9 2 0 0 2 2 2 0 Periplasmic binding proteins and sugar binding domain of LacI family DUF3479 PF11965.8 CAM43221.1 - 0.15 12.2 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3479) PK PF00224.21 CAM43223.1 - 5.6e-139 462.9 0.9 6.8e-139 462.6 0.9 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 CAM43223.1 - 6.6e-20 71.5 1.9 1.1e-19 70.8 0.1 2.3 3 0 0 3 3 3 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 CAM43223.1 - 4e-05 22.8 0.6 0.00013 21.2 0.7 1.8 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family DUF3479 PF11965.8 CAM43223.1 - 0.16 12.0 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3479) PK PF00224.21 CAM43224.1 - 2.2e-30 105.7 0.1 2.9e-30 105.4 0.1 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain DUF4401 PF14351.6 CAM43224.1 - 0.0019 17.6 1.2 0.0028 17.0 1.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) IMPDH PF00478.25 CAM43224.1 - 0.14 11.1 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain PI-PLC-X PF00388.19 CAM43225.1 - 8.7e-60 200.5 0.0 1.5e-59 199.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 CAM43225.1 - 4.5e-33 114.0 0.1 2e-32 111.9 0.0 2.1 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_1 PF00036.32 CAM43225.1 - 2e-05 23.8 1.6 4.3e-05 22.8 1.0 2.0 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 CAM43225.1 - 0.00035 21.0 0.1 0.00095 19.6 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CAM43225.1 - 0.00084 19.1 0.3 0.002 18.0 0.3 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_10 PF14788.6 CAM43225.1 - 0.016 15.0 1.6 0.034 14.0 1.6 1.6 1 0 0 1 1 1 0 EF hand C2 PF00168.30 CAM43225.1 - 0.023 15.0 0.0 0.055 13.8 0.0 1.6 1 0 0 1 1 1 0 C2 domain EF-hand_6 PF13405.6 CAM43225.1 - 0.036 14.0 3.1 0.038 13.9 1.1 2.2 2 0 0 2 2 2 0 EF-hand domain EF-hand_4 PF12763.7 CAM43225.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Transket_pyr PF02779.24 CAM43226.1 - 4.3e-39 134.0 0.0 9.3e-39 132.9 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CAM43226.1 - 2.5e-35 121.0 0.0 6.5e-35 119.7 0.0 1.6 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 CAM43226.1 - 1.1e-05 25.6 0.0 2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Band_7 PF01145.25 CAM43228.1 - 2.1e-24 86.5 4.6 3.5e-24 85.8 4.6 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family TrkH PF02386.16 CAM43229.1 - 1.6e-08 33.5 2.9 1.6e-08 33.5 2.9 3.4 3 1 0 3 3 3 3 Cation transport protein UCR_14kD PF02271.16 CAM43231.1 - 7.7e-08 32.2 0.1 4.5e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Clat_adaptor_s PF01217.20 CAM43232.1 - 1e-10 41.7 0.0 1.4e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain OSR1_C PF12202.8 CAM43232.1 - 0.13 12.5 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 Oxidative-stress-responsive kinase 1 C-terminal domain LMBR1 PF04791.16 CAM43233.1 - 3.5e-18 65.8 25.3 1.3e-13 50.7 6.3 2.1 1 1 1 2 2 2 2 LMBR1-like membrane protein Arf PF00025.21 CAM43234.2 - 4.5e-65 218.4 0.0 5.1e-65 218.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CAM43234.2 - 1.8e-13 50.4 1.7 2.3e-08 33.6 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 CAM43234.2 - 1.1e-11 45.1 0.0 1.4e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 CAM43234.2 - 3.2e-10 39.8 0.0 3.8e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CAM43234.2 - 2.3e-07 30.4 0.0 3e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CAM43234.2 - 6.1e-07 29.5 0.0 8.6e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 CAM43234.2 - 6.9e-07 29.0 0.0 8.4e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.27 CAM43234.2 - 0.00021 20.9 0.0 0.0018 17.8 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CAM43234.2 - 0.00096 18.7 0.1 0.0034 16.9 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B cobW PF02492.19 CAM43234.2 - 0.013 15.1 0.1 0.16 11.5 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TniB PF05621.11 CAM43234.2 - 0.18 11.2 0.2 0.52 9.7 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein Mito_carr PF00153.27 CAM43236.1 - 3.1e-06 27.0 3.1 0.057 13.3 0.0 2.6 2 1 0 2 2 2 2 Mitochondrial carrier protein SHE3 PF17078.5 CAM43239.1 - 0.00041 20.1 12.1 0.00041 20.1 12.1 6.9 1 1 2 5 5 5 2 SWI5-dependent HO expression protein 3 GAS PF13851.6 CAM43239.1 - 0.0043 16.4 6.2 0.0043 16.4 6.2 9.0 2 2 7 9 9 9 2 Growth-arrest specific micro-tubule binding MPS2 PF17060.5 CAM43239.1 - 0.0056 16.0 6.8 0.0056 16.0 6.8 6.4 3 2 3 6 6 6 3 Monopolar spindle protein 2 JIP_LZII PF16471.5 CAM43239.1 - 0.0069 16.5 7.2 0.0069 16.5 7.2 10.5 6 4 6 13 13 13 1 JNK-interacting protein leucine zipper II DUF3287 PF11690.8 CAM43239.1 - 0.06 13.1 2.0 0.46 10.2 2.0 2.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) M_domain PF12938.7 CAM43239.1 - 2.6 7.8 14.8 0.3 10.8 2.6 3.0 3 0 0 3 3 3 0 M domain of GW182 WD40_alt PF14077.6 CAM43239.1 - 6 6.8 11.1 53 3.8 0.2 5.0 4 0 0 4 4 4 0 Alternative WD40 repeat motif NIF PF03031.18 CAM43240.1 - 3.2e-32 111.5 0.0 4.5e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase PF00702.26 CAM43240.1 - 0.0002 21.7 0.0 0.00028 21.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CAM43240.1 - 0.0012 19.3 0.0 0.0053 17.2 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF705 PF05152.12 CAM43240.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) FlgM PF04316.13 CAM43241.1 - 0.32 11.4 9.2 0.35 11.2 2.2 5.2 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM DUF1242 PF06842.12 CAM43242.1 - 6.4e-10 38.7 1.7 9.4e-10 38.1 1.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) DnaJ PF00226.31 CAM43244.1 - 6.7e-05 22.9 0.0 0.00027 21.0 0.0 2.1 2 1 0 2 2 2 1 DnaJ domain zf_CCCH_4 PF18345.1 CAM43244.1 - 0.046 13.8 1.6 0.046 13.8 1.6 2.3 2 0 0 2 2 2 0 Zinc finger domain Torus PF16131.5 CAM43244.1 - 1.1 9.9 5.2 0.39 11.4 1.0 2.3 3 0 0 3 3 3 0 Torus domain zf-CCCH PF00642.24 CAM43244.1 - 1.2 9.2 8.9 0.054 13.4 3.0 1.9 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ribosomal_L7Ae PF01248.26 CAM43245.1 - 2.7e-24 84.7 0.0 3.1e-24 84.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family IF3_N PF05198.16 CAM43245.1 - 0.024 14.9 0.0 0.038 14.2 0.0 1.2 1 0 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain Hydrolase_6 PF13344.6 CAM43245.1 - 0.098 12.8 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase ArfGap PF01412.18 CAM43247.1 - 8e-29 100.1 0.1 1.6e-28 99.2 0.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PHO4 PF01384.20 CAM43248.1 - 0.14 11.2 0.2 0.14 11.2 0.2 1.0 1 0 0 1 1 1 0 Phosphate transporter family 3HCDH PF00725.22 CAM43250.1 - 2.1e-10 41.1 0.1 0.00048 20.7 0.0 2.6 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Nup96 PF12110.8 CAM43251.1 - 0.035 13.2 0.1 0.1 11.7 0.1 1.7 2 0 0 2 2 2 0 Nuclear protein 96 RRF PF01765.19 CAM43251.1 - 0.071 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Ribosome recycling factor Drc1-Sld2 PF11719.8 CAM43251.1 - 0.093 12.3 3.5 0.097 12.2 0.3 2.2 2 1 1 3 3 3 0 DNA replication and checkpoint protein Ank_2 PF12796.7 CAM43252.1 - 4.6e-10 40.0 0.0 7.1e-08 32.9 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CAM43252.1 - 6.7e-09 36.1 0.0 7.9e-05 23.1 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CAM43252.1 - 8.9e-08 31.8 0.1 0.0052 17.2 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 CAM43252.1 - 0.00027 21.2 0.1 0.035 14.6 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 CAM43252.1 - 0.00045 20.5 0.0 0.011 16.1 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) adh_short PF00106.25 CAM43254.1 - 1.6e-41 141.9 0.2 2.1e-41 141.5 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CAM43254.1 - 1.5e-25 90.1 0.4 2.1e-25 89.7 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CAM43254.1 - 1.6e-15 57.5 0.6 2.5e-15 56.8 0.6 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CAM43254.1 - 0.014 14.6 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TGBp3 PF02495.17 CAM43254.1 - 0.041 13.5 0.2 0.084 12.5 0.2 1.5 1 0 0 1 1 1 0 Triple gene block 3 Eno-Rase_NADH_b PF12242.8 CAM43254.1 - 0.072 12.9 0.1 0.2 11.4 0.1 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ECH_1 PF00378.20 CAM43257.1 - 4e-49 167.2 0.1 6.2e-49 166.6 0.1 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CAM43257.1 - 5.7e-25 88.5 0.3 2.9e-22 79.6 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Thioredoxin_8 PF13905.6 CAM43258.1 - 7.7e-05 22.9 0.1 0.015 15.6 0.0 2.4 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin PF00085.20 CAM43258.1 - 0.00011 22.2 0.0 0.00024 21.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CAM43258.1 - 0.053 14.0 0.1 0.23 11.9 0.1 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CAM43258.1 - 0.056 13.6 0.0 0.78 10.0 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_9 PF14595.6 CAM43258.1 - 0.18 11.6 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Ribosomal_S3Ae PF01015.18 CAM43260.1 - 5.1e-68 228.6 4.3 6e-68 228.4 4.3 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family DNA_pol3_delt_C PF14840.6 CAM43260.1 - 0.12 12.7 2.7 0.21 11.9 2.3 1.5 1 1 0 1 1 1 0 Processivity clamp loader gamma complex DNA pol III C-term Ribosomal_S3Ae PF01015.18 CAM43261.1 - 5.1e-68 228.6 4.3 6e-68 228.4 4.3 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family DNA_pol3_delt_C PF14840.6 CAM43261.1 - 0.12 12.7 2.7 0.21 11.9 2.3 1.5 1 1 0 1 1 1 0 Processivity clamp loader gamma complex DNA pol III C-term SHIPPO-rpt PF07004.12 CAM43262.2 - 2e-12 47.4 20.3 0.1 13.6 0.1 9.6 9 0 0 9 9 9 6 Sperm-tail PG-rich repeat Arrestin_N PF00339.29 CAM43263.1 - 1.1e-08 35.3 0.0 2.6e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain HAP2-GCS1 PF10699.9 CAM43265.1 - 5.4e-20 71.1 0.1 1.2e-19 70.1 0.1 1.6 1 0 0 1 1 1 1 Male gamete fusion factor DC_STAMP PF07782.13 CAM43265.1 - 0.47 10.3 3.4 0.28 11.0 0.4 2.0 2 0 0 2 2 2 0 DC-STAMP-like protein DUF4131 PF13567.6 CAM43265.1 - 0.86 9.2 4.7 10 5.7 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Pkinase PF00069.25 CAM43268.1 - 4.3e-51 173.8 0.1 1e-31 110.3 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CAM43268.1 - 6.8e-24 84.5 0.1 3e-17 62.8 0.1 3.3 3 0 0 3 3 3 2 Protein tyrosine kinase EF-hand_7 PF13499.6 CAM43268.1 - 3.3e-08 33.9 0.5 0.00095 19.6 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CAM43268.1 - 8.3e-08 31.6 0.0 0.016 15.1 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CAM43268.1 - 1.3e-05 24.4 0.0 0.11 12.1 0.0 3.3 3 0 0 3 3 3 2 EF hand Kinase-like PF14531.6 CAM43268.1 - 8.2e-05 22.0 0.0 0.087 12.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 CAM43268.1 - 0.034 13.5 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_8 PF13855.6 CAM43269.1 - 4.7e-25 87.1 17.6 0.00024 20.8 0.3 7.5 6 2 2 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 CAM43269.1 - 8.5e-21 73.7 8.7 0.00055 20.3 0.4 7.1 7 0 0 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CAM43269.1 - 3.5e-05 23.8 10.6 23 6.0 0.1 8.1 9 0 0 9 9 9 2 Leucine Rich Repeat SOG2 PF10428.9 CAM43269.1 - 0.23 10.6 71.8 0.36 10.0 71.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein LRR_4 PF12799.7 CAM43270.1 - 6.6e-15 55.0 12.9 0.0071 16.7 0.9 6.0 5 1 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM43270.1 - 5.6e-12 45.2 11.2 3.5e-06 26.7 1.6 4.1 2 2 3 5 5 5 5 Leucine rich repeat LRR_1 PF00560.33 CAM43270.1 - 0.84 10.4 5.9 2.3e+02 3.0 0.0 6.2 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.6 CAM43271.1 - 8.1e-16 57.5 15.1 7.3e-06 25.7 3.7 4.5 2 2 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 CAM43271.1 - 4.2e-14 52.4 13.9 0.015 15.7 0.9 5.3 4 1 1 5 5 5 5 Leucine Rich repeats (2 copies) RXLR PF16810.5 CAM43271.1 - 0.12 12.7 5.1 1.4e+02 2.9 5.1 7.1 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity LRR_1 PF00560.33 CAM43271.1 - 1.5 9.7 7.5 1.2e+02 3.8 0.1 6.2 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_8 PF13855.6 CAM43272.1 - 2.1e-17 62.6 2.7 0.00015 21.5 0.9 5.4 5 0 0 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 CAM43272.1 - 2e-11 44.0 5.2 0.0044 17.4 0.5 6.1 4 2 1 6 6 6 3 Leucine Rich repeats (2 copies) SPX PF03105.19 CAM43272.1 - 0.0048 16.9 20.0 0.0048 16.9 20.0 1.8 2 0 0 2 2 2 1 SPX domain LRR_1 PF00560.33 CAM43272.1 - 0.79 10.5 5.6 1.2e+02 3.9 0.1 6.4 8 0 0 8 8 8 0 Leucine Rich Repeat SOG2 PF10428.9 CAM43272.1 - 0.82 8.8 35.9 0.037 13.2 28.8 2.0 2 0 0 2 2 2 0 RAM signalling pathway protein GCOM2 PF15328.6 CAM43272.1 - 2.1 8.7 9.7 35 4.7 8.0 2.3 2 0 0 2 2 2 0 Putative GRINL1B complex locus protein 2 Presenilin PF01080.17 CAM43272.1 - 7.1 5.3 6.8 14 4.3 6.8 1.4 1 0 0 1 1 1 0 Presenilin PIP5K PF01504.18 CAM43273.1 - 3.6e-59 200.2 0.0 1.2e-58 198.6 0.0 1.9 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF4763 PF15960.5 CAM43273.1 - 0.6 9.4 9.5 0.27 10.5 1.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) WD40 PF00400.32 CAM43274.2 - 1.6e-05 25.6 25.3 0.0013 19.5 3.0 6.7 8 0 0 8 8 8 3 WD domain, G-beta repeat Keratin PF02422.16 CAM43274.2 - 0.007 16.0 0.4 0.007 16.0 0.4 2.9 3 0 0 3 3 3 1 Keratin Nucleoporin_N PF08801.11 CAM43274.2 - 0.17 10.6 0.0 2.9 6.5 0.0 2.5 3 0 0 3 3 3 0 Nup133 N terminal like Snf7 PF03357.21 CAM43275.2 - 1.4e-40 138.7 19.8 1.6e-40 138.5 19.8 1.0 1 0 0 1 1 1 1 Snf7 XRN_M PF17846.1 CAM43275.2 - 0.056 12.4 7.9 0.077 11.9 7.9 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Hydantoinase_B PF02538.14 CAM43275.2 - 0.1 11.0 1.5 0.12 10.7 1.5 1.1 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase Ndr PF03096.14 CAM43275.2 - 0.11 11.2 2.8 0.14 10.9 2.8 1.1 1 0 0 1 1 1 0 Ndr family NPV_P10 PF05531.12 CAM43275.2 - 0.11 13.0 9.9 0.046 14.2 4.2 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Rotamase_2 PF13145.6 CAM43275.2 - 0.12 13.2 2.2 0.2 12.5 2.2 1.4 1 0 0 1 1 1 0 PPIC-type PPIASE domain FlaC_arch PF05377.11 CAM43275.2 - 0.33 11.4 4.0 15 6.1 0.8 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF3573 PF12097.8 CAM43275.2 - 0.49 9.2 4.6 0.63 8.8 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Activator_LAG-3 PF11498.8 CAM43275.2 - 2.5 7.0 18.6 3 6.7 18.6 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Ribosomal_L18A PF01775.17 CAM43277.2 - 3.4e-40 136.9 1.2 4.5e-40 136.5 1.2 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Nup35_RRM_2 PF14605.6 CAM43280.1 - 1.6e-13 50.4 0.0 2.6e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Glyco_hydro_32N PF00251.20 CAM43281.1 - 5.4e-53 180.5 6.5 1e-52 179.6 6.5 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 CAM43281.1 - 9.8e-15 54.9 0.0 3.2e-14 53.2 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal PAN_4 PF14295.6 CAM43281.1 - 0.0004 20.2 5.9 0.0015 18.4 5.9 2.1 1 0 0 1 1 1 1 PAN domain zf-C3HC4_2 PF13923.6 CAM43282.1 - 0.00048 19.9 6.5 0.00048 19.9 6.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CAM43282.1 - 0.0058 16.9 8.1 0.0058 16.9 8.1 3.1 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 CAM43282.1 - 0.008 16.2 5.2 0.008 16.2 5.2 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.6 CAM43282.1 - 0.01 15.7 4.4 0.01 15.7 4.4 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-C3HC4 PF00097.25 CAM43282.1 - 0.19 11.6 12.5 0.02 14.8 6.7 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CAM43282.1 - 0.58 10.1 10.3 0.25 11.2 6.3 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CAM43282.1 - 1.1 9.2 12.9 0.22 11.5 7.3 2.6 2 0 0 2 2 2 0 zinc-RING finger domain DUF1272 PF06906.11 CAM43282.1 - 1.7 8.8 8.9 1.3 9.2 5.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-rbx1 PF12678.7 CAM43282.1 - 2.3 8.6 7.7 1.2 9.4 2.5 2.7 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 CAM43282.1 - 7.2 6.9 14.8 0.12 12.6 7.3 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Dynein_AAA_lid PF17852.1 CAM43283.2 - 0.48 10.5 3.1 25 5.0 0.1 4.4 4 0 0 4 4 4 0 Dynein heavy chain AAA lid domain TPR_12 PF13424.6 CAM43285.2 - 1.3e-59 198.4 40.7 5.3e-14 52.3 1.6 8.4 5 3 2 8 8 8 8 Tetratricopeptide repeat TPR_10 PF13374.6 CAM43285.2 - 2.8e-42 141.5 26.7 3.3e-06 26.8 0.2 12.3 12 0 0 12 12 12 9 Tetratricopeptide repeat TPR_2 PF07719.17 CAM43285.2 - 7.4e-21 72.5 43.0 0.0043 17.1 0.1 12.3 12 1 0 12 12 12 6 Tetratricopeptide repeat TPR_1 PF00515.28 CAM43285.2 - 1.7e-19 68.7 40.8 5.1e-05 22.9 0.0 12.2 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_8 PF13181.6 CAM43285.2 - 2.3e-19 67.9 37.3 0.044 14.0 0.0 12.3 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_7 PF13176.6 CAM43285.2 - 8.1e-16 56.8 22.6 0.001 18.9 0.1 9.9 11 1 0 11 11 11 4 Tetratricopeptide repeat TPR_16 PF13432.6 CAM43285.2 - 2e-12 47.6 24.8 0.0051 17.4 0.1 8.2 6 2 1 8 8 8 3 Tetratricopeptide repeat TPR_MalT PF17874.1 CAM43285.2 - 5.4e-08 32.6 15.8 0.0023 17.3 5.9 4.1 2 1 3 5 5 5 4 MalT-like TPR region TPR_14 PF13428.6 CAM43285.2 - 4.6e-07 30.1 31.5 4.4 8.4 0.0 11.2 9 2 3 12 12 12 1 Tetratricopeptide repeat TPR_19 PF14559.6 CAM43285.2 - 1e-06 29.1 23.8 0.035 14.6 0.7 7.4 8 0 0 8 8 8 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 CAM43285.2 - 0.0061 16.0 0.1 37 3.9 0.0 4.5 5 0 0 5 5 5 0 SHNi-TPR SET_assoc PF11767.8 CAM43285.2 - 0.028 14.1 0.0 0.076 12.7 0.0 1.7 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated TPR_17 PF13431.6 CAM43285.2 - 1.7 9.2 19.7 16 6.2 0.1 7.5 8 1 0 8 8 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CAM43285.2 - 1.8 8.8 36.2 0.41 10.9 0.7 7.6 4 4 4 8 8 8 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 CAM43285.2 - 3.4 7.7 7.1 4.7 7.3 1.7 3.3 3 2 1 4 4 3 0 Domain of Unknown Function (DUF3856) TPR_11 PF13414.6 CAM43285.2 - 5.3 6.8 12.7 27 4.6 0.0 5.9 6 1 1 7 7 7 0 TPR repeat ATP-synt_D PF01813.17 CAM43286.1 - 1.1e-72 244.1 1.0 1.1e-72 244.1 1.0 1.5 2 0 0 2 2 2 1 ATP synthase subunit D Exo_endo_phos PF03372.23 CAM43287.1 - 4.9e-06 26.2 0.0 8.6e-06 25.4 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SET PF00856.28 CAM43289.1 - 4.1e-11 43.5 0.6 2.7e-07 31.1 0.1 3.3 2 1 0 2 2 2 2 SET domain DUF4670 PF15709.5 CAM43289.1 - 1 8.6 8.1 2.3 7.5 8.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4670) FHA PF00498.26 CAM43290.2 - 0.0039 17.5 0.0 0.0083 16.5 0.0 1.6 1 1 0 1 1 1 1 FHA domain PA28_beta PF02252.18 CAM43291.1 - 3.9e-10 39.6 0.0 1.3e-05 25.0 0.0 2.3 2 0 0 2 2 2 2 Proteasome activator pa28 beta subunit CBS PF00571.28 CAM43292.1 - 1.8e-16 60.3 0.8 0.00076 19.9 0.0 4.3 4 0 0 4 4 4 4 CBS domain RrnaAD PF00398.20 CAM43293.1 - 1.6e-25 89.7 0.0 3.2e-15 55.9 0.0 2.0 2 0 0 2 2 2 2 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 CAM43293.1 - 0.0016 19.1 0.0 0.0042 17.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 CAM43293.1 - 0.15 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_23 PF13489.6 CAM43293.1 - 0.18 11.6 0.0 0.6 9.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Actin PF00022.19 CAM43295.1 - 8.3e-58 195.9 0.0 1.1e-44 152.7 0.0 2.0 2 0 0 2 2 2 2 Actin Aminotran_1_2 PF00155.21 CAM43298.1 - 1.4e-66 225.2 0.0 1.6e-66 225.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II FAD_binding_2 PF00890.24 CAM43299.1 - 1e-83 281.8 0.1 1.5e-83 281.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain ApbE PF02424.15 CAM43299.1 - 1.5e-48 165.5 0.0 7.7e-48 163.3 0.0 2.0 1 1 0 1 1 1 1 ApbE family NAD_binding_1 PF00175.21 CAM43299.1 - 1.3e-16 61.2 0.0 2.6e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DAO PF01266.24 CAM43299.1 - 1.1e-12 48.2 2.1 3e-12 46.8 1.7 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 CAM43299.1 - 6e-10 39.0 4.1 1.5e-09 37.7 3.6 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_6 PF00970.24 CAM43299.1 - 8.1e-09 35.7 0.0 1.9e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Pyr_redox_2 PF07992.14 CAM43299.1 - 2e-08 33.8 0.1 5.6e-08 32.4 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CAM43299.1 - 6.9e-07 29.4 1.1 3.1e-06 27.3 1.1 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 CAM43299.1 - 2.4e-06 26.9 5.7 8.5e-06 25.1 4.2 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 CAM43299.1 - 3.1e-06 26.6 0.6 7.1e-06 25.5 0.6 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 CAM43299.1 - 0.00034 19.4 5.1 0.00076 18.3 3.1 2.4 2 1 0 2 2 2 1 HI0933-like protein NAD_binding_6 PF08030.12 CAM43299.1 - 0.004 17.3 0.0 0.052 13.7 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Pyr_redox PF00070.27 CAM43299.1 - 0.0055 17.2 1.2 0.015 15.9 1.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CAM43299.1 - 0.0098 15.2 0.7 0.058 12.6 0.5 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CAM43299.1 - 0.055 12.7 1.0 0.087 12.1 1.0 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 CAM43299.1 - 0.14 11.2 1.0 0.22 10.5 1.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein DUF2838 PF10998.8 CAM43301.1 - 1.6e-14 54.1 22.3 3.9e-09 36.7 6.5 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF2838) Telomere_reg-2 PF10193.9 CAM43303.1 - 0.00026 21.4 0.0 0.015 15.7 0.0 3.1 2 0 0 2 2 2 1 Telomere length regulation protein VWA_2 PF13519.6 CAM43304.1 - 0.19 12.4 0.4 0.88 10.2 0.0 2.2 2 0 0 2 2 2 0 von Willebrand factor type A domain Arabinose_Isome PF02610.15 CAM43305.1 - 0.012 14.9 0.3 0.021 14.1 0.3 1.4 1 0 0 1 1 1 0 L-arabinose isomerase GP120 PF00516.18 CAM43305.1 - 0.015 13.9 0.9 0.021 13.4 0.9 1.3 1 1 0 1 1 1 0 Envelope glycoprotein GP120 UPF0203 PF05254.12 CAM43305.1 - 0.034 14.4 1.9 0.33 11.2 1.9 2.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) COX6B PF02297.17 CAM43305.1 - 0.44 10.8 4.8 6.6 7.0 0.5 2.3 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb T6SS_TssF PF05947.12 CAM43308.1 - 0.14 10.7 0.1 0.18 10.3 0.1 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssF FAM131 PF15010.6 CAM43309.2 - 0.056 13.3 0.4 0.072 13.0 0.4 1.1 1 0 0 1 1 1 0 Putative cell signalling DUF1682 PF07946.14 CAM43309.2 - 0.65 9.1 5.3 0.94 8.6 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PhrC_PhrF PF11131.8 CAM43309.2 - 3.2 7.4 8.4 8.3 6.1 0.1 2.9 3 0 0 3 3 3 0 Rap-phr extracellular signalling PSP1 PF04468.12 CAM43311.1 - 3.8e-23 81.6 0.3 8.5e-23 80.4 0.3 1.6 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Cupin_8 PF13621.6 CAM43312.2 - 0.047 13.4 0.0 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 Cupin-like domain Aldose_epim PF01263.20 CAM43314.1 - 8.8e-30 104.0 0.0 9.9e-30 103.9 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Pkinase PF00069.25 CAM43316.1 - 2.5e-25 89.4 0.0 3.1e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM43316.1 - 3.4e-15 56.0 0.0 4.6e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAM43316.1 - 2e-12 46.6 0.2 2.8e-12 46.2 0.2 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CAM43316.1 - 4.2e-05 23.6 0.1 0.0001 22.3 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 CAM43317.1 - 1.3e-24 87.0 0.0 1.9e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM43317.1 - 4.5e-13 49.1 0.0 5.7e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAM43317.1 - 1e-08 34.4 0.0 1.3e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CAM43317.1 - 0.0001 22.3 0.0 0.00024 21.1 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CAM43317.1 - 0.0081 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-CCCH PF00642.24 CAM43318.1 - 9.2e-05 22.3 6.3 0.00018 21.4 6.3 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CAM43318.1 - 1.9 8.7 6.1 3.5 7.8 6.1 1.5 1 0 0 1 1 1 0 Zinc finger domain Cupin_5 PF06172.11 CAM43319.1 - 1.6e-41 141.7 0.0 2.2e-41 141.3 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily (DUF985) zf-CCCH PF00642.24 CAM43320.1 - 1e-06 28.5 1.0 1e-06 28.5 1.0 2.9 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CAM43320.1 - 0.00027 20.9 0.8 0.00069 19.6 0.8 1.8 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_2 PF14608.6 CAM43320.1 - 0.017 15.6 0.6 0.043 14.3 0.6 1.8 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 CAM43320.1 - 0.061 13.1 1.2 0.16 11.8 1.2 1.8 1 0 0 1 1 1 0 CCCH-type zinc finger STT3 PF02516.14 CAM43322.1 - 7.6e-46 157.1 21.3 4.1e-42 144.7 17.9 2.0 1 1 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PMT PF02366.18 CAM43322.1 - 0.057 13.0 13.6 0.013 15.1 9.0 2.1 2 0 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Wzy_C PF04932.15 CAM43322.1 - 0.23 11.1 2.7 0.91 9.1 2.7 2.1 1 0 0 1 1 1 0 O-Antigen ligase STT3 PF02516.14 CAM43323.1 - 7.8e-41 140.5 30.1 1.3e-40 139.8 30.1 1.3 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit STT3 PF02516.14 CAM43324.1 - 3.9e-45 154.7 20.9 1.6e-43 149.4 20.9 2.1 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit DUF1358 PF07096.11 CAM43324.1 - 0.043 13.8 0.6 0.15 12.0 0.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1358) Rhodanese PF00581.20 CAM43325.1 - 4e-09 37.0 0.0 1.1e-08 35.6 0.0 1.7 2 0 0 2 2 2 1 Rhodanese-like domain FAD_binding_2 PF00890.24 CAM43326.1 - 1.6e-84 284.4 0.3 2.4e-84 283.8 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain ApbE PF02424.15 CAM43326.1 - 3.3e-55 187.4 0.0 5.7e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 ApbE family NAD_binding_1 PF00175.21 CAM43326.1 - 2.5e-18 66.7 0.0 7.5e-18 65.2 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DAO PF01266.24 CAM43326.1 - 3.8e-10 39.9 4.7 2.9e-09 37.0 4.7 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 CAM43326.1 - 4.4e-09 36.2 4.2 1.4e-08 34.6 4.2 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CAM43326.1 - 7.6e-09 35.2 0.7 2.5e-08 33.5 0.2 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_6 PF00970.24 CAM43326.1 - 5e-08 33.2 0.0 1.1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CAM43326.1 - 6.1e-07 29.7 0.0 0.0019 18.4 0.0 2.6 2 0 0 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_8 PF13450.6 CAM43326.1 - 2.1e-06 27.8 2.5 6.1e-06 26.4 1.3 2.5 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 CAM43326.1 - 3.8e-06 26.3 1.0 8.8e-06 25.2 1.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 CAM43326.1 - 4.5e-06 26.0 8.0 4.2e-05 22.8 4.0 2.7 3 0 0 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.14 CAM43326.1 - 0.00014 20.7 4.9 0.0012 17.6 2.9 2.4 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 CAM43326.1 - 0.00019 20.8 0.2 0.011 15.0 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CAM43326.1 - 0.0017 18.9 2.2 0.0025 18.3 0.5 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CAM43326.1 - 0.0042 16.4 0.7 0.0069 15.7 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 CAM43326.1 - 0.13 11.3 3.0 0.51 9.3 1.4 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 CAM43326.1 - 0.21 10.8 4.6 0.16 11.2 1.0 2.6 3 0 0 3 3 3 0 Thi4 family FAD_binding_2 PF00890.24 CAM43327.1 - 4.9e-92 309.2 0.2 5.8e-92 308.9 0.2 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CAM43327.1 - 2.4e-09 37.3 7.0 4.9e-08 32.9 6.8 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CAM43327.1 - 6.6e-09 35.4 0.3 1.8e-08 34.0 0.3 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CAM43327.1 - 7.4e-09 35.5 3.0 1.3e-08 34.6 3.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CAM43327.1 - 2.8e-08 33.9 0.6 1.3e-07 31.8 0.6 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 CAM43327.1 - 0.00058 19.1 3.9 0.00058 19.1 3.9 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 CAM43327.1 - 0.00059 19.2 2.7 0.084 12.1 1.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CAM43327.1 - 0.00069 18.4 7.1 0.0028 16.4 1.0 3.2 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.17 CAM43327.1 - 0.012 14.8 2.3 0.073 12.3 0.5 2.5 3 0 0 3 3 3 0 Thi4 family FAD_binding_3 PF01494.19 CAM43327.1 - 0.014 14.7 1.1 0.018 14.3 1.1 1.3 1 1 0 1 1 1 0 FAD binding domain Sacchrp_dh_NADP PF03435.18 CAM43327.1 - 0.018 15.3 0.4 0.2 11.9 0.7 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 CAM43327.1 - 0.022 14.1 1.1 0.046 13.0 1.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 CAM43327.1 - 0.15 12.7 3.2 0.12 12.9 0.8 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CAM43327.1 - 0.18 10.8 1.6 12 4.9 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 CAM43328.1 - 6.3e-72 242.9 0.0 8e-72 242.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain HA2 PF04408.23 CAM43329.1 - 1.3e-18 67.3 0.0 3.8e-18 65.8 0.0 1.8 2 0 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CAM43329.1 - 1.8e-14 54.0 0.0 5.3e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CAM43329.1 - 4.3e-14 52.6 0.1 1e-13 51.4 0.1 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 CAM43329.1 - 1.4e-08 34.7 0.1 7e-08 32.4 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CAM43329.1 - 1.2e-06 28.9 0.1 3e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CAM43329.1 - 0.00041 19.9 0.0 0.0014 18.2 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region T2SSE PF00437.20 CAM43329.1 - 0.00067 18.8 0.0 0.0014 17.7 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 CAM43329.1 - 0.0011 19.4 0.0 0.0025 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CAM43329.1 - 0.0038 17.3 0.0 0.37 10.8 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CAM43329.1 - 0.011 15.5 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CAM43329.1 - 0.036 14.6 0.2 1.1 9.8 0.1 2.5 1 1 1 2 2 2 0 ABC transporter Sigma54_activat PF00158.26 CAM43329.1 - 0.055 13.2 0.0 0.43 10.3 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain SRP54 PF00448.22 CAM43329.1 - 0.096 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 CAM43329.1 - 0.12 12.7 0.2 0.54 10.6 0.2 2.1 1 1 0 1 1 1 0 AAA ATPase domain Sigma54_activ_2 PF14532.6 CAM43329.1 - 0.15 12.2 0.0 0.91 9.6 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain Armet PF10208.9 CAM43330.1 - 1.1e-07 31.8 0.0 2.4e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding SAP PF02037.27 CAM43330.1 - 0.0085 15.8 0.0 0.02 14.6 0.0 1.7 1 0 0 1 1 1 1 SAP domain adh_short PF00106.25 CAM43331.1 - 1.6e-46 158.3 1.2 1.9e-46 158.0 1.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CAM43331.1 - 5.3e-33 114.5 0.8 6.7e-33 114.2 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CAM43331.1 - 2.7e-11 43.7 0.1 3.5e-11 43.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CAM43331.1 - 0.0036 16.8 0.1 0.009 15.5 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CAM43331.1 - 0.012 15.0 0.3 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase QRPTase_C PF01729.19 CAM43331.1 - 0.027 14.3 0.1 0.044 13.6 0.1 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Polysacc_synt_2 PF02719.15 CAM43331.1 - 0.033 13.3 0.4 0.045 12.9 0.4 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DUF871 PF05913.11 CAM43331.1 - 0.12 11.5 0.1 0.17 11.1 0.1 1.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF871) adh_short PF00106.25 CAM43332.1 - 1.8e-36 125.5 0.0 4.5e-36 124.2 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CAM43332.1 - 4.4e-20 72.2 0.0 1.3e-19 70.7 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CAM43332.1 - 3.2e-05 23.9 0.1 6.5e-05 22.9 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 CAM43332.1 - 0.00046 19.7 0.2 0.0029 17.1 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HTH_Tnp_Tc3_1 PF11427.8 CAM43333.1 - 0.36 10.7 1.9 1.8 8.5 0.3 3.1 3 0 0 3 3 3 0 Tc3 transposase Glutaredoxin PF00462.24 CAM43334.1 - 6.4e-18 64.7 3.1 1.9e-13 50.4 0.1 3.1 3 0 0 3 3 3 2 Glutaredoxin Thioredoxin PF00085.20 CAM43334.1 - 7.5e-14 51.6 0.3 1.4e-13 50.7 0.2 1.5 2 0 0 2 2 2 1 Thioredoxin OST3_OST6 PF04756.13 CAM43334.1 - 0.00052 19.5 0.0 0.00069 19.0 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 CAM43334.1 - 0.0011 19.0 0.1 0.0023 18.1 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 CAM43334.1 - 0.0036 17.0 0.2 0.007 16.1 0.2 1.5 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 CAM43334.1 - 0.0042 17.4 0.0 0.01 16.1 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 CAM43334.1 - 0.015 15.2 0.1 0.025 14.5 0.1 1.5 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_6 PF13848.6 CAM43334.1 - 0.033 14.1 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain AAA PF00004.29 CAM43335.1 - 6.4e-36 123.7 0.0 1.6e-35 122.4 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CAM43335.1 - 1e-07 32.0 0.0 3.2e-07 30.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CAM43335.1 - 2.7e-07 30.5 0.0 9.2e-07 28.7 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CAM43335.1 - 5.4e-07 30.1 0.1 2.2e-05 24.9 0.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_lid_3 PF17862.1 CAM43335.1 - 1.9e-06 27.6 0.0 4.8e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 CAM43335.1 - 2.1e-06 27.2 0.0 1.2e-05 24.8 0.0 2.0 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_22 PF13401.6 CAM43335.1 - 7.5e-06 26.3 0.3 0.0014 18.9 0.0 2.7 2 1 0 3 3 2 1 AAA domain AAA_33 PF13671.6 CAM43335.1 - 1.4e-05 25.3 0.0 3.1e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CAM43335.1 - 5.9e-05 23.6 0.0 0.00011 22.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CAM43335.1 - 0.00021 21.1 0.0 0.00035 20.4 0.0 1.4 1 1 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 CAM43335.1 - 0.00048 20.5 0.0 0.001 19.4 0.0 1.6 1 1 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 CAM43335.1 - 0.0012 18.9 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 CAM43335.1 - 0.0018 18.3 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 CAM43335.1 - 0.002 17.5 0.1 0.0061 15.9 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_24 PF13479.6 CAM43335.1 - 0.0024 17.6 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CAM43335.1 - 0.0028 17.2 0.1 0.012 15.2 0.0 2.1 2 1 0 2 2 2 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 CAM43335.1 - 0.0032 16.9 0.0 0.0065 15.9 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 CAM43335.1 - 0.0033 17.7 0.2 0.009 16.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain SKI PF01202.22 CAM43335.1 - 0.0039 17.3 0.0 0.015 15.4 0.0 1.9 2 0 0 2 2 2 1 Shikimate kinase AAA_3 PF07726.11 CAM43335.1 - 0.0039 17.0 0.0 0.013 15.4 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 CAM43335.1 - 0.0096 16.1 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.26 CAM43335.1 - 0.011 15.5 0.0 0.038 13.7 0.0 1.9 2 1 0 2 2 2 0 Sigma-54 interaction domain Rad17 PF03215.15 CAM43335.1 - 0.012 15.6 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 CAM43335.1 - 0.017 15.0 0.0 0.036 14.0 0.0 1.6 1 1 0 1 1 1 0 NACHT domain Sigma54_activ_2 PF14532.6 CAM43335.1 - 0.018 15.2 0.0 0.064 13.4 0.0 1.9 2 0 0 2 2 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 CAM43335.1 - 0.021 13.9 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Cytidylate_kin PF02224.18 CAM43335.1 - 0.022 14.5 0.1 0.082 12.6 0.0 1.9 2 0 0 2 2 2 0 Cytidylate kinase AAA_29 PF13555.6 CAM43335.1 - 0.029 14.1 0.0 0.081 12.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 CAM43335.1 - 0.031 13.9 0.2 0.16 11.5 0.1 2.1 2 1 0 3 3 2 0 AAA domain DUF815 PF05673.13 CAM43335.1 - 0.038 13.1 0.0 0.1 11.8 0.0 1.9 2 1 0 2 2 1 0 Protein of unknown function (DUF815) AAA_11 PF13086.6 CAM43335.1 - 0.05 13.4 0.0 0.082 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 CAM43335.1 - 0.055 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CAM43335.1 - 0.072 13.6 0.1 1.7 9.2 0.0 2.5 1 1 2 3 3 2 0 ABC transporter AAA_6 PF12774.7 CAM43335.1 - 0.073 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region PhoH PF02562.16 CAM43335.1 - 0.076 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein PPV_E1_C PF00519.17 CAM43335.1 - 0.084 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase DUF2075 PF09848.9 CAM43335.1 - 0.15 11.3 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MMR_HSR1 PF01926.23 CAM43335.1 - 0.17 12.0 0.1 1.6 8.8 0.0 2.3 2 1 0 2 2 2 0 50S ribosome-binding GTPase 2OG-FeII_Oxy_2 PF13532.6 CAM43337.1 - 3.2e-08 34.0 0.0 4.8e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 CAM43337.1 - 0.021 15.3 0.0 0.12 12.8 0.0 2.1 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily ORC_WH_C PF18137.1 CAM43338.2 - 0.049 13.7 2.4 0.97 9.5 0.0 2.1 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal DUF3464 PF11947.8 CAM43338.2 - 1.2 8.9 3.8 7 6.4 1.8 2.2 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 UQ_con PF00179.26 CAM43339.1 - 7.1e-55 184.5 0.0 8e-55 184.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CAM43339.1 - 0.0063 16.8 0.0 0.0074 16.6 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 CAM43339.1 - 0.15 11.8 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B CENP-T_C PF15511.6 CAM43340.1 - 1.9e-05 24.8 0.1 3e-05 24.1 0.1 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CAM43340.1 - 0.00024 21.3 0.4 0.00032 20.9 0.0 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 CAM43340.1 - 0.00034 20.7 0.1 0.00053 20.1 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 CAM43340.1 - 0.00078 19.8 1.9 0.0015 18.9 1.9 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 CAM43340.1 - 0.0012 18.8 0.0 0.0014 18.6 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 CAM43340.1 - 0.033 14.2 0.0 0.043 13.9 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Thioredoxin PF00085.20 CAM43342.1 - 3.2e-14 52.7 0.0 9.3e-14 51.3 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CAM43342.1 - 0.0074 16.7 0.8 0.097 13.1 0.3 2.8 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_6 PF13848.6 CAM43342.1 - 0.047 13.6 0.1 4.2 7.2 0.0 2.7 2 1 0 2 2 2 0 Thioredoxin-like domain OST3_OST6 PF04756.13 CAM43342.1 - 0.09 12.1 0.1 0.25 10.6 0.1 1.8 1 1 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 CAM43342.1 - 0.094 13.1 0.1 0.53 10.6 0.1 2.4 2 1 0 2 2 2 0 Thioredoxin-like Endonuc_subdom PF09062.10 CAM43342.1 - 0.14 13.0 0.3 12 6.8 0.1 2.5 2 0 0 2 2 2 0 PI-PfuI Endonuclease subdomain DUF1028 PF06267.12 CAM43343.1 - 0.038 13.8 0.0 0.054 13.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF1028) POX PF07526.11 CAM43343.1 - 0.12 12.9 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 Associated with HOX zf-CDGSH PF09360.10 CAM43346.1 - 7e-19 67.8 5.9 9.5e-10 38.5 0.3 2.2 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type Peptidase_M16 PF00675.20 CAM43347.1 - 4.8e-27 94.8 0.0 8e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CAM43347.1 - 2.4e-14 53.7 0.0 4.9e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain OTU PF02338.19 CAM43348.1 - 1.1e-16 61.5 0.0 2e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease zf-RanBP PF00641.18 CAM43348.1 - 0.00013 21.2 1.8 0.00013 21.2 1.8 4.9 5 0 0 5 5 5 3 Zn-finger in Ran binding protein and others Peptidase_C65 PF10275.9 CAM43348.1 - 0.00021 20.8 0.1 0.17 11.3 0.0 2.4 1 1 1 2 2 2 2 Peptidase C65 Otubain zf-RRN7 PF11781.8 CAM43348.1 - 0.01 15.5 1.7 0.01 15.5 1.7 3.1 4 0 0 4 4 4 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-tcix PF14952.6 CAM43348.1 - 0.034 13.7 0.3 0.034 13.7 0.3 3.9 3 1 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding zf-ribbon_3 PF13248.6 CAM43348.1 - 0.085 12.3 0.0 0.085 12.3 0.0 4.0 4 0 0 4 4 4 0 zinc-ribbon domain RRM_1 PF00076.22 CAM43349.1 - 1.3e-06 28.1 0.0 0.059 13.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cytochrom_NNT PF03264.14 CAM43349.1 - 0.037 13.7 0.5 0.07 12.8 0.5 1.4 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region tRNA-synt_2b PF00587.25 CAM43350.1 - 5.2e-31 108.0 0.0 7.9e-28 97.6 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CAM43350.1 - 8.5e-18 64.3 0.1 2e-17 63.1 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 CAM43350.1 - 1.8e-13 50.3 0.0 4.7e-13 49.0 0.0 1.8 2 0 0 2 2 2 1 TGS domain tRNA_SAD PF07973.14 CAM43350.1 - 2e-11 43.8 0.0 3.5e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TPR_1 PF00515.28 CAM43351.1 - 5e-21 73.6 4.7 9.9e-07 28.3 0.1 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 CAM43351.1 - 9.8e-19 65.9 7.8 7.3e-06 25.7 0.1 6.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 CAM43351.1 - 3.8e-18 64.5 6.7 8.4e-05 22.7 0.8 5.4 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 CAM43351.1 - 8.9e-18 63.7 7.3 1.3e-05 24.7 0.7 5.4 3 2 2 5 5 5 3 TPR repeat TPR_14 PF13428.6 CAM43351.1 - 3.5e-16 58.5 11.3 2.5e-05 24.7 0.0 6.8 3 2 4 7 7 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 CAM43351.1 - 5.5e-13 49.3 7.0 8.2e-08 32.8 0.3 4.5 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 CAM43351.1 - 1.3e-11 44.8 13.6 5.2e-06 26.9 0.2 4.9 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 CAM43351.1 - 1.3e-10 40.6 2.7 0.005 16.9 0.0 6.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 CAM43351.1 - 4.9e-07 29.3 0.2 2.1 8.6 0.0 5.2 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CAM43351.1 - 1.1e-06 28.8 2.6 0.00017 21.8 0.1 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 CAM43351.1 - 2.3e-05 24.5 2.7 0.00018 21.6 0.2 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 CAM43351.1 - 0.002 18.0 9.4 2.1 8.4 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat BTAD PF03704.17 CAM43351.1 - 0.062 13.7 7.0 0.34 11.3 0.0 3.2 3 1 1 4 4 4 0 Bacterial transcriptional activator domain TPR_6 PF13174.6 CAM43351.1 - 0.11 13.1 15.6 1 10.2 0.0 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CAM43351.1 - 0.27 11.3 1.0 4.6 7.4 0.1 3.4 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 CAM43351.1 - 0.37 11.0 3.5 1 9.6 0.2 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 CAM43351.1 - 3.1 8.2 22.3 1.3 9.4 0.1 5.1 4 1 2 6 6 5 0 Tetratricopeptide repeat Ribosomal_L2_C PF03947.18 CAM43352.1 - 5.5e-43 146.2 3.5 1.2e-42 145.1 2.1 2.0 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CAM43352.1 - 4.2e-13 49.1 0.1 1.2e-12 47.6 0.1 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Ribosomal_L2_C PF03947.18 CAM43353.1 - 5.5e-43 146.2 3.5 1.2e-42 145.1 2.1 2.0 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CAM43353.1 - 4.2e-13 49.1 0.1 1.2e-12 47.6 0.1 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Sigma70_r4 PF04545.16 CAM43354.2 - 7.9e-07 28.5 0.0 41 3.8 0.0 7.2 7 0 0 7 7 7 5 Sigma-70, region 4 Benyvirus_14KDa PF07255.11 CAM43355.2 - 0.12 12.6 0.0 0.48 10.6 0.0 1.9 2 0 0 2 2 2 0 Benyvirus 14KDa protein Choline_kinase PF01633.20 CAM43356.2 - 2.2e-31 109.1 0.0 2.6e-30 105.6 0.0 2.2 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CAM43356.2 - 3.3e-10 40.3 0.0 1.2e-07 31.9 0.0 2.8 2 1 0 2 2 2 2 Phosphotransferase enzyme family Arginase PF00491.21 CAM43357.1 - 1.7e-72 244.3 0.0 2e-72 244.1 0.0 1.0 1 0 0 1 1 1 1 Arginase family Ependymin PF00811.18 CAM43358.1 - 0.075 13.3 0.3 2.4 8.4 0.2 2.2 2 0 0 2 2 2 0 Ependymin NIF PF03031.18 CAM43359.1 - 1.2e-19 70.6 0.0 2.5e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase zf-CCCH PF00642.24 CAM43359.1 - 0.00014 21.7 1.8 0.00028 20.7 1.8 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CAM43359.1 - 0.0067 16.4 0.1 0.02 14.9 0.1 1.8 1 0 0 1 1 1 1 Zinc finger domain Rieske PF00355.26 CAM43362.1 - 1.1e-12 47.8 0.0 2.4e-12 46.6 0.0 1.5 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain PIN_3 PF13470.6 CAM43364.2 - 1.4 9.7 3.5 1.5 9.6 0.1 2.8 3 0 0 3 3 3 0 PIN domain Methyltransf_23 PF13489.6 CAM43365.1 - 8.4e-19 68.0 0.0 1.3e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAM43365.1 - 5e-12 46.3 0.0 9.9e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAM43365.1 - 1.1e-10 42.0 0.0 2.2e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CAM43365.1 - 5.5e-09 35.7 0.0 7.8e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 CAM43365.1 - 1.8e-07 31.1 0.0 3.5e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAM43365.1 - 2.3e-07 31.4 0.0 8.6e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Peptidase_C14 PF00656.22 CAM43366.1 - 1.8e-48 165.6 0.0 2.4e-48 165.3 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Mei5 PF10376.9 CAM43367.1 - 0.0051 16.7 4.1 0.0093 15.9 4.1 1.4 1 0 0 1 1 1 1 Double-strand recombination repair protein DUF2273 PF10031.9 CAM43367.1 - 0.033 14.2 0.1 0.059 13.4 0.1 1.4 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) Cauli_AT PF03233.13 CAM43367.1 - 0.4 10.6 3.0 0.74 9.7 3.0 1.4 1 0 0 1 1 1 0 Aphid transmission protein BST2 PF16716.5 CAM43367.1 - 1.1 9.9 9.9 7.7 7.2 0.9 2.5 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 DUF1664 PF07889.12 CAM43367.1 - 1.2 9.1 3.7 2.8 8.0 3.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Laminin_G_3 PF13385.6 CAM43370.2 - 8.8e-13 48.7 0.2 2.4e-12 47.3 0.0 1.9 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily DUF2972 PF11186.8 CAM43370.2 - 0.11 12.4 1.2 0.19 11.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2972) Ribosomal_L10 PF00466.20 CAM43370.2 - 0.22 11.7 0.6 1.7 8.8 0.2 2.5 2 0 0 2 2 2 0 Ribosomal protein L10 EF-hand_7 PF13499.6 CAM43371.1 - 0.00032 21.1 0.0 0.00062 20.2 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CAM43371.1 - 0.047 13.3 0.0 2.4 7.9 0.0 2.4 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.6 CAM43371.1 - 0.051 13.4 0.0 12 5.8 0.0 2.3 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 CAM43371.1 - 0.052 13.5 0.0 11 6.3 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain DUF1180 PF06679.12 CAM43371.1 - 2.6 8.4 16.8 0.42 11.0 5.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) baeRF_family11 PF18855.1 CAM43372.2 - 0.022 15.1 0.5 0.043 14.1 0.5 1.5 1 1 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 11 NYD-SP28_assoc PF14775.6 CAM43373.1 - 0.1 12.7 0.2 0.1 12.7 0.2 5.8 5 1 1 6 6 6 0 Sperm tail C-terminal domain MutL_C PF08676.11 CAM43374.1 - 1.8e-29 102.4 0.0 3.3e-29 101.5 0.0 1.4 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 CAM43374.1 - 9.4e-12 44.7 0.0 1.7e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CAM43374.1 - 1.8e-06 27.8 0.0 4.2e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CAM43374.1 - 0.019 15.5 0.0 0.05 14.1 0.0 1.9 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_L26 PF16906.5 CAM43375.1 - 1.8e-37 127.7 1.3 2.3e-37 127.3 1.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 CAM43375.1 - 4e-06 26.6 0.5 1e-05 25.3 0.5 1.8 1 1 0 1 1 1 1 KOW motif LRR_8 PF13855.6 CAM43377.1 - 8.2e-13 47.9 18.1 0.0021 17.7 1.3 4.5 2 2 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 CAM43377.1 - 2.3e-11 43.7 13.6 0.0024 18.2 0.2 4.8 2 1 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CAM43377.1 - 1.1e-07 31.3 7.9 2.8 8.2 0.2 6.7 6 0 0 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.33 CAM43377.1 - 6.4e-06 26.0 10.1 8.3 7.4 0.0 6.8 6 1 0 6 6 6 1 Leucine Rich Repeat LRR_9 PF14580.6 CAM43377.1 - 0.00099 18.7 2.9 0.35 10.4 0.0 3.0 2 1 1 3 3 3 2 Leucine-rich repeat EzrA PF06160.12 CAM43377.1 - 0.04 12.1 5.2 0.056 11.6 5.2 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Spc29 PF17082.5 CAM43377.1 - 0.064 13.1 2.1 0.11 12.3 2.1 1.5 1 0 0 1 1 1 0 Spindle Pole Component 29 DUF4685 PF15737.5 CAM43377.1 - 0.75 10.2 9.0 1.4 9.4 0.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4685) Takusan PF04822.13 CAM43377.1 - 1.8 8.5 7.3 5.5 6.9 7.3 1.9 1 1 0 1 1 1 0 Takusan DivIVA PF05103.13 CAM43377.1 - 2.8 8.0 11.7 1 9.5 2.8 2.3 1 1 1 2 2 2 0 DivIVA protein RTC PF01137.21 CAM43378.2 - 2.1e-42 144.8 0.1 2.4e-42 144.7 0.1 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 CAM43378.2 - 1.1e-27 96.5 0.1 1.8e-27 95.8 0.1 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Pro_isomerase PF00160.21 CAM43379.1 - 2.3e-08 34.5 0.0 3.6e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.25 CAM43380.1 - 3.6e-58 197.0 0.0 4.2e-58 196.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM43380.1 - 2.5e-18 66.3 0.0 3.4e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CAM43380.1 - 1.8e-05 24.8 0.0 0.0017 18.4 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CAM43380.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like UCH PF00443.29 CAM43381.1 - 5.4e-48 163.7 0.4 9.4e-48 162.9 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CAM43381.1 - 2.8e-20 73.2 0.4 1.5e-18 67.4 0.2 2.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 CAM43381.1 - 3e-09 36.9 0.0 1.4e-08 34.7 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin-specific protease C-terminal USP7_ICP0_bdg PF12436.8 CAM43381.1 - 4.4e-09 36.0 0.1 1.1e-08 34.7 0.0 1.7 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 Robl_LC7 PF03259.17 CAM43382.1 - 3.9e-20 71.4 0.0 4.3e-20 71.3 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 CAM43382.1 - 2.6e-06 27.2 0.0 3.2e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 CRM1_repeat_2 PF18784.1 CAM43382.1 - 0.095 12.3 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 CRM1 / Exportin repeat 2 Notch PF00066.17 CAM43383.1 - 0.23 11.9 0.8 0.56 10.7 0.8 1.6 1 0 0 1 1 1 0 LNR domain Proteasom_Rpn13 PF04683.13 CAM43385.1 - 3.5e-14 53.1 0.0 5.5e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 CAM43385.1 - 1e-12 48.2 0.0 1.7e-12 47.5 0.0 1.4 1 1 0 1 1 1 1 UCH-binding domain DUF4205 PF13898.6 CAM43385.1 - 0.1 11.5 0.6 0.33 9.8 0.4 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4205) RskA PF10099.9 CAM43386.1 - 0.0085 16.4 0.1 0.013 15.8 0.1 1.5 1 1 0 1 1 1 1 Anti-sigma-K factor rskA Pox_MCEL PF03291.16 CAM43386.1 - 0.08 12.0 0.2 0.12 11.5 0.2 1.3 1 1 0 1 1 1 0 mRNA capping enzyme BRE1 PF08647.11 CAM43386.1 - 0.78 9.8 9.6 0.07 13.2 1.5 2.2 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase TMF_DNA_bd PF12329.8 CAM43386.1 - 0.89 9.6 12.0 3.6 7.7 2.0 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DNA_pol_E_B PF04042.16 CAM43387.1 - 2.4e-19 69.5 0.0 3.8e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DTW PF03942.15 CAM43388.1 - 3e-22 79.3 0.1 5.8e-22 78.4 0.1 1.5 1 0 0 1 1 1 1 DTW domain Glyco_hydro_2_N PF02837.18 CAM43388.1 - 0.035 14.0 0.1 0.055 13.4 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain zinc_ribbon_9 PF14369.6 CAM43388.1 - 0.17 12.2 4.6 3.3 8.1 0.5 2.6 1 1 1 2 2 2 0 zinc-ribbon zf-B_box PF00643.24 CAM43388.1 - 0.26 11.5 2.3 0.43 10.8 2.3 1.3 1 0 0 1 1 1 0 B-box zinc finger GAS PF13851.6 CAM43389.1 - 9e-58 194.9 28.2 9e-58 194.9 28.2 3.3 2 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding DivIC PF04977.15 CAM43389.1 - 0.011 15.4 3.0 0.011 15.4 3.0 6.4 3 3 4 7 7 7 0 Septum formation initiator TMF_TATA_bd PF12325.8 CAM43389.1 - 0.021 15.1 5.8 0.021 15.1 5.8 4.9 1 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF948 PF06103.11 CAM43389.1 - 0.023 15.0 15.8 3 8.2 5.4 4.9 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TetR_C_31 PF17940.1 CAM43389.1 - 0.24 11.6 0.0 0.24 11.6 0.0 2.8 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain Baculo_PEP_C PF04513.12 CAM43389.1 - 7.4 6.6 16.3 13 5.8 1.7 4.0 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DDE_Tnp_4 PF13359.6 CAM43389.1 - 9.4 5.9 7.9 17 5.1 0.8 2.7 1 1 1 2 2 2 0 DDE superfamily endonuclease Ebp2 PF05890.12 CAM43390.1 - 5.4e-44 150.8 12.6 1.3e-43 149.6 12.6 1.5 1 1 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 EF-1_beta_acid PF10587.9 CAM43390.1 - 0.14 12.6 0.3 0.14 12.6 0.3 4.3 4 1 0 4 4 4 0 Eukaryotic elongation factor 1 beta central acidic region SPEG_u2 PF16650.5 CAM43390.1 - 0.16 12.1 0.1 0.16 12.1 0.1 2.0 2 0 0 2 2 2 0 Unstructured region on SPEG complex protein GvpL_GvpF PF06386.11 CAM43390.1 - 1.2 9.0 11.6 0.049 13.6 1.6 2.2 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Lysine_decarbox PF03641.14 CAM43391.1 - 0.024 14.7 0.0 0.056 13.5 0.0 1.7 1 0 0 1 1 1 0 Possible lysine decarboxylase EMP24_GP25L PF01105.24 CAM43393.1 - 5.1e-40 137.4 0.2 6.9e-40 136.9 0.2 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD MogR_DNAbind PF12181.8 CAM43393.1 - 0.067 13.1 0.7 0.098 12.6 0.7 1.2 1 0 0 1 1 1 0 DNA binding domain of the motility gene repressor (MogR) Pkinase PF00069.25 CAM43394.1 - 9.9e-51 172.6 0.0 1.3e-50 172.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM43394.1 - 7.9e-20 71.2 0.0 1.3e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 CAM43394.1 - 0.14 11.7 0.1 0.24 11.0 0.1 1.3 1 0 0 1 1 1 0 RIO1 family GAF_2 PF13185.6 CAM43395.1 - 0.072 13.4 0.5 1.2 9.5 0.1 3.1 3 1 1 4 4 4 0 GAF domain TRAF_BIRC3_bd PF16673.5 CAM43395.1 - 0.078 12.8 0.5 0.2 11.5 0.5 1.6 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain BLOC1_2 PF10046.9 CAM43395.1 - 0.38 11.1 2.9 2.5 8.5 1.1 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ribosomal_L5e PF17144.4 CAM43396.1 - 2.9e-76 255.0 0.7 5e-76 254.2 0.7 1.4 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 CAM43396.1 - 2.5e-26 92.5 9.3 2.5e-26 92.5 9.3 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 CAM43396.1 - 0.0044 17.4 1.0 0.007 16.7 0.0 1.8 2 0 0 2 2 2 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast P53_C PF11619.8 CAM43396.1 - 0.12 12.4 0.0 8.8 6.5 0.0 2.4 2 0 0 2 2 2 0 Transcription factor P53 - C terminal domain Ribosomal_L5e PF17144.4 CAM43397.1 - 2.9e-76 255.0 0.7 5e-76 254.2 0.7 1.4 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 CAM43397.1 - 2.5e-26 92.5 9.3 2.5e-26 92.5 9.3 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 CAM43397.1 - 0.0044 17.4 1.0 0.007 16.7 0.0 1.8 2 0 0 2 2 2 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast P53_C PF11619.8 CAM43397.1 - 0.12 12.4 0.0 8.8 6.5 0.0 2.4 2 0 0 2 2 2 0 Transcription factor P53 - C terminal domain Ribosomal_L15e PF00827.17 CAM43398.1 - 2.2e-84 282.0 9.1 2.5e-84 281.8 9.1 1.0 1 0 0 1 1 1 1 Ribosomal L15 Ribosomal_L36e PF01158.18 CAM43399.1 - 2.1e-28 98.4 2.5 2.4e-28 98.2 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e PHD PF00628.29 CAM43401.1 - 0.00025 20.9 1.3 0.00073 19.4 1.3 1.8 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 CAM43401.1 - 0.99 9.3 10.5 0.46 10.4 5.4 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_Oberon PF07227.11 CAM43401.1 - 1.4 8.9 8.6 12 5.8 5.6 2.5 2 0 0 2 2 2 0 PHD - plant homeodomain finger protein TMCO5 PF14992.6 CAM43402.1 - 0.0014 18.3 5.9 0.0017 18.0 5.1 1.4 2 0 0 2 2 2 1 TMCO5 family UPF0242 PF06785.11 CAM43402.1 - 0.23 11.6 6.8 0.39 10.8 6.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus NYD-SP28_assoc PF14775.6 CAM43402.1 - 1.5 9.0 9.0 0.73 10.0 1.5 2.5 1 1 1 2 2 2 0 Sperm tail C-terminal domain PRKG1_interact PF15898.5 CAM43402.1 - 5 8.1 13.2 1.1 10.1 1.4 2.8 1 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Cep57_CLD_2 PF14197.6 CAM43402.1 - 5.9 7.1 15.9 89 3.3 15.8 2.3 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 ATP11 PF06644.11 CAM43403.1 - 2.7e-20 73.3 0.5 4.6e-20 72.5 0.5 1.3 1 1 0 1 1 1 1 ATP11 protein UBX PF00789.20 CAM43405.1 - 1.2e-07 31.9 0.0 3.7e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 UBX domain Thioredoxin_7 PF13899.6 CAM43405.1 - 0.34 11.1 1.9 1.3 9.3 0.0 2.9 3 0 0 3 3 3 0 Thioredoxin-like XRN_M PF17846.1 CAM43405.1 - 0.42 9.5 2.5 0.56 9.1 2.5 1.2 1 0 0 1 1 1 0 Xrn1 helical domain Asp-B-Hydro_N PF05279.11 CAM43405.1 - 1.7 8.7 16.0 2.5 8.1 16.0 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF572 PF04502.13 CAM43405.1 - 2.6 7.6 11.2 3.8 7.0 11.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Presenilin PF01080.17 CAM43405.1 - 2.7 6.7 7.8 3.6 6.2 7.8 1.1 1 0 0 1 1 1 0 Presenilin HnRNPA1 PF11627.8 CAM43406.1 - 0.023 14.9 0.6 0.055 13.7 0.6 1.6 1 0 0 1 1 1 0 Nuclear factor hnRNPA1 U1snRNP70_N PF12220.8 CAM43406.1 - 4.9 7.9 8.3 0.99 10.1 0.6 3.0 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal U3_assoc_6 PF08640.11 CAM43407.1 - 1.1e-16 60.7 0.7 3.9e-16 58.9 0.4 2.1 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 DUF2694 PF10904.8 CAM43407.1 - 0.11 12.6 2.3 0.81 9.8 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2694) Ribosomal_S6e PF01092.19 CAM43409.1 - 3.7e-39 133.6 0.0 7.7e-39 132.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e DnaB_bind PF10410.9 CAM43409.1 - 0.43 10.8 5.2 0.29 11.4 1.0 2.6 3 0 0 3 3 3 0 DnaB-helicase binding domain of primase RdRP_3 PF00998.23 CAM43409.1 - 0.65 8.6 6.1 0.78 8.4 6.1 1.1 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase RmlD_sub_bind PF04321.17 CAM43410.1 - 0.00015 21.0 0.0 0.073 12.2 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain AAA_lid_7 PF17867.1 CAM43410.1 - 0.17 12.1 0.1 0.6 10.3 0.0 1.9 2 0 0 2 2 2 0 Midasin AAA lid domain EF-hand_6 PF13405.6 CAM43411.2 - 1.9e-07 30.5 0.0 0.22 11.5 0.1 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CAM43411.2 - 1.3e-05 24.4 0.0 0.22 11.2 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 CAM43411.2 - 2.4e-05 24.7 0.0 0.55 10.7 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 CAM43411.2 - 0.15 11.9 0.1 39 4.2 0.1 3.2 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_5 PF13202.6 CAM43411.2 - 0.16 11.5 0.0 0.36 10.4 0.0 1.7 1 0 0 1 1 1 0 EF hand Ank_2 PF12796.7 CAM43412.2 - 1.1e-61 205.3 22.6 2.3e-09 37.7 0.0 14.9 11 4 4 15 15 15 10 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CAM43412.2 - 5.6e-38 128.5 32.1 1.7e-06 28.2 0.3 17.7 13 3 4 17 17 17 9 Ankyrin repeats (many copies) Ank_4 PF13637.6 CAM43412.2 - 2.4e-28 98.1 27.3 0.0011 19.5 0.0 15.3 15 3 3 18 18 18 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 CAM43412.2 - 2.6e-23 79.6 46.7 0.058 14.0 0.1 20.8 24 0 0 24 24 24 9 Ankyrin repeat Ank PF00023.30 CAM43412.2 - 3.1e-21 74.8 53.9 0.02 15.3 0.2 17.8 18 1 0 18 18 18 8 Ankyrin repeat Filamin PF00630.19 CAM43412.2 - 0.00081 20.2 0.0 0.0032 18.3 0.0 2.0 2 0 0 2 2 2 1 Filamin/ABP280 repeat Ribosomal_L32e PF01655.18 CAM43413.1 - 1.8e-39 134.5 0.1 2.2e-39 134.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 CdiI PF07262.11 CAM43413.1 - 0.11 12.2 0.5 0.17 11.6 0.1 1.5 2 0 0 2 2 2 0 CDI immunity protein SH3_9 PF14604.6 CAM43414.1 - 1e-32 111.8 1.0 1.6e-11 43.9 0.0 4.7 5 0 0 5 5 5 3 Variant SH3 domain SH3_1 PF00018.28 CAM43414.1 - 8e-28 95.8 0.7 1.5e-10 40.5 0.0 3.4 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 CAM43414.1 - 2.3e-25 88.0 1.0 5.5e-12 45.2 0.2 3.8 3 0 0 3 3 3 3 Variant SH3 domain TackOD1 PF18551.1 CAM43414.1 - 0.094 12.4 0.6 0.22 11.1 0.6 1.5 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 DUF4205 PF13898.6 CAM43415.1 - 1.3e-20 73.7 0.0 2.2e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) SLIDE PF09111.10 CAM43415.1 - 0.72 9.9 3.4 1.4 8.9 3.4 1.4 1 0 0 1 1 1 0 SLIDE E1-E2_ATPase PF00122.20 CAM43416.1 - 4.8e-43 146.8 0.8 4.8e-43 146.8 0.8 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CAM43416.1 - 6e-28 97.8 4.6 6e-28 97.8 4.6 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CAM43416.1 - 5.7e-16 59.4 0.0 7.9e-15 55.7 0.0 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CAM43416.1 - 2.7e-14 53.0 0.1 7.3e-14 51.6 0.1 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CAM43416.1 - 2.3e-09 36.8 0.0 5.2e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CAM43416.1 - 2e-06 27.7 2.1 2.3e-05 24.3 0.3 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Kinesin PF00225.23 CAM43417.1 - 8.2e-72 241.9 0.0 9.7e-43 146.4 0.0 2.5 3 0 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 CAM43417.1 - 5.5e-22 78.3 0.0 1.3e-21 77.1 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding Seryl_tRNA_N PF02403.22 CAM43417.1 - 6.1 7.1 6.9 2.9 8.2 4.1 1.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PKI PF02827.16 CAM43420.2 - 0.049 13.9 0.7 0.11 12.7 0.7 1.6 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor Synaptobrevin PF00957.21 CAM43421.1 - 5.5e-14 51.7 0.1 8.9e-14 51.1 0.1 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CAM43421.1 - 6.5e-07 29.3 0.0 1.1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Herpes_teg_N PF04843.12 CAM43421.1 - 0.12 12.1 0.1 0.47 10.1 0.1 2.0 2 1 1 3 3 3 0 Herpesvirus tegument protein, N-terminal conserved region CDC45 PF02724.14 CAM43422.1 - 0.00072 18.0 6.1 0.00085 17.7 6.1 1.1 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 CAM43422.1 - 0.0045 16.5 16.6 0.0045 16.5 16.6 1.3 2 0 0 2 2 2 1 SDA1 DUF4303 PF14136.6 CAM43422.1 - 0.58 9.9 9.4 10 5.8 6.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4303) Presenilin PF01080.17 CAM43422.1 - 4.8 5.9 7.5 6.8 5.3 7.5 1.2 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 CAM43422.1 - 7.3 4.7 26.9 11 4.1 26.9 1.2 1 0 0 1 1 1 0 Nop14-like family Lipase_3 PF01764.25 CAM43424.1 - 3.6e-05 23.7 0.0 8.4e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 CAM43424.1 - 0.0017 18.1 0.1 0.0033 17.2 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 CAM43424.1 - 0.039 14.0 0.0 0.15 12.1 0.0 2.0 1 0 0 1 1 1 0 Thioesterase domain Complex1_LYR PF05347.15 CAM43424.1 - 0.42 10.7 2.7 1.4 9.0 2.9 1.8 2 0 0 2 2 2 0 Complex 1 protein (LYR family) adh_short PF00106.25 CAM43425.1 - 3e-18 66.0 0.2 1.3e-15 57.4 0.1 3.1 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CAM43425.1 - 3.3e-08 33.4 0.0 7.4e-07 29.0 0.0 2.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase YjeF_N PF03853.15 CAM43425.1 - 0.1 12.5 0.1 0.3 11.0 0.1 1.7 1 1 0 1 1 1 0 YjeF-related protein N-terminus A_deaminase PF00962.22 CAM43426.1 - 2.4e-58 198.0 0.0 3.1e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase adh_short PF00106.25 CAM43427.1 - 1.9e-13 50.3 0.3 7.2e-13 48.4 0.1 2.1 3 0 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 CAM43427.1 - 2e-08 34.1 0.7 2.9e-07 30.3 0.2 2.7 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CAM43427.1 - 0.0082 16.1 2.1 0.02 14.8 0.8 2.2 3 0 0 3 3 3 1 KR domain 3HCDH_N PF02737.18 CAM43427.1 - 0.066 13.1 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ribosomal_L11_N PF03946.14 CAM43429.1 - 1.1e-16 60.5 0.5 1.8e-16 59.7 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CAM43429.1 - 1.7e-13 50.8 2.0 1.7e-13 50.8 0.8 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain RRM_1 PF00076.22 CAM43430.1 - 1.3e-35 121.0 0.0 5e-17 61.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 CAM43430.1 - 5.1e-05 23.1 0.0 0.17 11.7 0.0 2.2 2 0 0 2 2 2 2 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 CAM43430.1 - 0.0046 17.1 0.0 0.16 12.1 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif KMP11 PF03037.16 CAM43431.1 - 1.4e-56 189.2 18.4 1.6e-56 189.1 18.4 1.0 1 0 0 1 1 1 1 Kinetoplastid membrane protein 11 Apolipoprotein PF01442.18 CAM43431.1 - 0.0026 17.7 3.4 0.0079 16.1 3.4 1.7 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Lyase_8_N PF08124.11 CAM43431.1 - 0.014 14.3 1.6 0.014 14.3 1.6 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain DUF3987 PF13148.6 CAM43431.1 - 0.17 10.8 2.8 0.19 10.7 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) ABC_membrane_3 PF13748.6 CAM43431.1 - 0.2 10.9 0.1 0.28 10.4 0.1 1.3 1 1 0 1 1 1 0 ABC transporter transmembrane region Adhesin_P1_N PF18652.1 CAM43431.1 - 0.22 11.6 2.8 7.7 6.6 0.2 2.3 1 1 1 2 2 2 0 Adhesin P1 N-terminal domain TipAS PF07739.13 CAM43431.1 - 0.34 11.5 10.0 0.5 10.9 2.9 2.0 1 1 0 2 2 2 0 TipAS antibiotic-recognition domain DUF4890 PF16231.5 CAM43431.1 - 0.35 11.4 9.2 0.39 11.2 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4890) HAD_2 PF13419.6 CAM43431.1 - 0.41 10.7 4.4 0.45 10.6 4.4 1.1 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase ZnuA PF01297.17 CAM43431.1 - 0.42 10.0 5.2 0.9 8.9 0.3 2.0 1 1 1 2 2 2 0 Zinc-uptake complex component A periplasmic YtxH PF12732.7 CAM43431.1 - 0.43 11.2 2.6 2.3 8.8 2.6 1.9 1 1 0 1 1 1 0 YtxH-like protein Metal_resist PF13801.6 CAM43431.1 - 0.84 9.8 3.4 2.1 8.5 0.3 2.0 1 1 1 2 2 2 0 Heavy-metal resistance DUF2884 PF11101.8 CAM43431.1 - 2.3 7.6 7.5 4.5 6.7 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) Muted PF14942.6 CAM43431.1 - 5.7 7.3 14.6 4.6 7.6 1.0 2.0 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein OmpH PF03938.14 CAM43431.1 - 5.8 7.3 11.6 16 5.9 11.6 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) KMP11 PF03037.16 CAM43432.1 - 1.4e-56 189.2 18.4 1.6e-56 189.1 18.4 1.0 1 0 0 1 1 1 1 Kinetoplastid membrane protein 11 Apolipoprotein PF01442.18 CAM43432.1 - 0.0026 17.7 3.4 0.0079 16.1 3.4 1.7 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Lyase_8_N PF08124.11 CAM43432.1 - 0.014 14.3 1.6 0.014 14.3 1.6 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain DUF3987 PF13148.6 CAM43432.1 - 0.17 10.8 2.8 0.19 10.7 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) ABC_membrane_3 PF13748.6 CAM43432.1 - 0.2 10.9 0.1 0.28 10.4 0.1 1.3 1 1 0 1 1 1 0 ABC transporter transmembrane region Adhesin_P1_N PF18652.1 CAM43432.1 - 0.22 11.6 2.8 7.7 6.6 0.2 2.3 1 1 1 2 2 2 0 Adhesin P1 N-terminal domain TipAS PF07739.13 CAM43432.1 - 0.34 11.5 10.0 0.5 10.9 2.9 2.0 1 1 0 2 2 2 0 TipAS antibiotic-recognition domain DUF4890 PF16231.5 CAM43432.1 - 0.35 11.4 9.2 0.39 11.2 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4890) HAD_2 PF13419.6 CAM43432.1 - 0.41 10.7 4.4 0.45 10.6 4.4 1.1 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase ZnuA PF01297.17 CAM43432.1 - 0.42 10.0 5.2 0.9 8.9 0.3 2.0 1 1 1 2 2 2 0 Zinc-uptake complex component A periplasmic YtxH PF12732.7 CAM43432.1 - 0.43 11.2 2.6 2.3 8.8 2.6 1.9 1 1 0 1 1 1 0 YtxH-like protein Metal_resist PF13801.6 CAM43432.1 - 0.84 9.8 3.4 2.1 8.5 0.3 2.0 1 1 1 2 2 2 0 Heavy-metal resistance DUF2884 PF11101.8 CAM43432.1 - 2.3 7.6 7.5 4.5 6.7 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) Muted PF14942.6 CAM43432.1 - 5.7 7.3 14.6 4.6 7.6 1.0 2.0 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein OmpH PF03938.14 CAM43432.1 - 5.8 7.3 11.6 16 5.9 11.6 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) KMP11 PF03037.16 CAM43433.1 - 1.4e-56 189.2 18.4 1.6e-56 189.1 18.4 1.0 1 0 0 1 1 1 1 Kinetoplastid membrane protein 11 Apolipoprotein PF01442.18 CAM43433.1 - 0.0026 17.7 3.4 0.0079 16.1 3.4 1.7 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Lyase_8_N PF08124.11 CAM43433.1 - 0.014 14.3 1.6 0.014 14.3 1.6 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain DUF3987 PF13148.6 CAM43433.1 - 0.17 10.8 2.8 0.19 10.7 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) ABC_membrane_3 PF13748.6 CAM43433.1 - 0.2 10.9 0.1 0.28 10.4 0.1 1.3 1 1 0 1 1 1 0 ABC transporter transmembrane region Adhesin_P1_N PF18652.1 CAM43433.1 - 0.22 11.6 2.8 7.7 6.6 0.2 2.3 1 1 1 2 2 2 0 Adhesin P1 N-terminal domain TipAS PF07739.13 CAM43433.1 - 0.34 11.5 10.0 0.5 10.9 2.9 2.0 1 1 0 2 2 2 0 TipAS antibiotic-recognition domain DUF4890 PF16231.5 CAM43433.1 - 0.35 11.4 9.2 0.39 11.2 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4890) HAD_2 PF13419.6 CAM43433.1 - 0.41 10.7 4.4 0.45 10.6 4.4 1.1 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase ZnuA PF01297.17 CAM43433.1 - 0.42 10.0 5.2 0.9 8.9 0.3 2.0 1 1 1 2 2 2 0 Zinc-uptake complex component A periplasmic YtxH PF12732.7 CAM43433.1 - 0.43 11.2 2.6 2.3 8.8 2.6 1.9 1 1 0 1 1 1 0 YtxH-like protein Metal_resist PF13801.6 CAM43433.1 - 0.84 9.8 3.4 2.1 8.5 0.3 2.0 1 1 1 2 2 2 0 Heavy-metal resistance DUF2884 PF11101.8 CAM43433.1 - 2.3 7.6 7.5 4.5 6.7 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) Muted PF14942.6 CAM43433.1 - 5.7 7.3 14.6 4.6 7.6 1.0 2.0 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein OmpH PF03938.14 CAM43433.1 - 5.8 7.3 11.6 16 5.9 11.6 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) ATG_C PF09333.11 CAM43436.2 - 0.011 16.1 0.1 0.54 10.6 0.1 2.9 1 1 0 1 1 1 0 Autophagy-related protein C terminal domain Peptidase_A17 PF05380.13 CAM43437.1 - 0.0035 17.3 0.1 0.044 13.8 0.0 2.4 1 1 1 2 2 2 1 Pao retrotransposon peptidase RVT_1 PF00078.27 CAM43437.1 - 0.0035 16.9 0.0 0.0091 15.5 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_integrase PF00589.22 CAM43437.1 - 0.059 13.2 0.0 0.32 10.8 0.0 2.3 2 0 0 2 2 2 0 Phage integrase family ATP-grasp_4 PF13535.6 CAM43438.1 - 5.9e-10 39.0 0.0 2.1e-08 33.9 0.0 2.3 1 1 0 1 1 1 1 ATP-grasp domain LAL_C2 PF18603.1 CAM43438.1 - 7.7e-06 26.0 0.0 1.7e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 L-amino acid ligase C-terminal domain 2 ATPgrasp_Ter PF15632.6 CAM43438.1 - 0.00028 20.7 0.1 0.17 11.6 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 CAM43438.1 - 0.0013 18.8 0.0 0.012 15.7 0.0 2.3 1 1 0 1 1 1 1 ATP-grasp domain Helicase_C PF00271.31 CAM43439.1 - 1.3e-08 35.1 0.0 3.4e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CAM43439.1 - 3.3e-05 23.7 0.0 9e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CAM43439.1 - 0.052 13.8 0.0 0.25 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 CAM43444.1 - 4e-43 147.7 0.1 2.6e-15 56.5 0.1 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CAM43444.1 - 2.8e-25 89.1 0.0 4.5e-22 78.6 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CAM43444.1 - 9.9e-05 21.8 0.0 0.0048 16.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CAM43444.1 - 0.14 10.9 0.0 0.26 10.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase UCR_6-4kD PF08997.10 CAM43444.1 - 0.2 11.6 0.0 0.46 10.5 0.0 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein HEAT_EZ PF13513.6 CAM43445.2 - 4.9e-09 36.5 7.4 0.00032 21.1 0.0 5.8 5 1 1 6 6 6 2 HEAT-like repeat HEAT PF02985.22 CAM43445.2 - 3.4e-06 26.8 4.4 3.7 8.1 0.0 7.3 6 0 0 6 6 6 1 HEAT repeat RIX1 PF08167.12 CAM43445.2 - 0.018 14.8 1.7 14 5.4 0.2 3.8 4 1 0 4 4 4 0 rRNA processing/ribosome biogenesis Arm PF00514.23 CAM43445.2 - 0.028 14.5 3.3 13 6.0 0.3 4.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat TAF6_C PF07571.13 CAM43445.2 - 0.029 14.7 0.0 38 4.7 0.0 4.1 4 1 0 4 4 4 0 TAF6 C-terminal HEAT repeat domain 2Fe-2S_thioredx PF01257.19 CAM43445.2 - 0.089 12.7 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin IBN_N PF03810.19 CAM43445.2 - 0.13 12.2 2.5 0.35 10.8 0.6 2.6 2 0 0 2 2 2 0 Importin-beta N-terminal domain IFRD PF05004.13 CAM43445.2 - 4.5 6.3 4.8 12 4.9 0.0 3.6 3 2 2 5 5 5 0 Interferon-related developmental regulator (IFRD) CAF1 PF04857.20 CAM43446.2 - 1.4e-49 169.0 0.0 2.1e-49 168.4 0.0 1.3 1 0 0 1 1 1 1 CAF1 family ribonuclease NUT PF12881.7 CAM43446.2 - 0.098 11.1 0.1 0.15 10.4 0.1 1.1 1 0 0 1 1 1 0 NUT protein Peptidase_M24 PF00557.24 CAM43447.1 - 5.9e-52 176.4 1.4 8.5e-52 175.9 1.4 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CAM43447.1 - 1.5e-25 89.3 0.0 4.7e-25 87.7 0.0 1.8 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain DUF1764 PF08576.10 CAM43448.1 - 1.2e-07 32.5 3.7 2.3e-07 31.6 2.0 2.2 1 1 1 2 2 2 1 Eukaryotic protein of unknown function (DUF1764) SET PF00856.28 CAM43449.2 - 0.00018 21.9 0.0 0.0061 17.0 0.0 3.0 2 1 0 2 2 2 1 SET domain Spt4 PF06093.13 CAM43451.1 - 4.1e-10 39.6 0.0 5.2e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger WD40 PF00400.32 CAM43452.1 - 2.1e-05 25.2 0.3 0.6 11.1 0.0 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM43452.1 - 7.8e-05 22.9 0.1 0.11 12.8 0.0 4.2 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Prenyltrans PF00432.21 CAM43452.1 - 0.11 12.3 0.0 0.33 10.7 0.0 1.8 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat UCH PF00443.29 CAM43453.2 - 1.7e-35 122.8 0.0 5e-29 101.6 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CAM43453.2 - 2e-14 53.9 0.5 3.9e-13 49.7 0.2 2.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Vps5 PF09325.10 CAM43454.2 - 5.4e-17 62.1 4.1 7.7e-17 61.6 4.1 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 CAM43454.2 - 6.7e-16 58.3 0.0 1.5e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 PX domain P4Ha_N PF08336.11 CAM43454.2 - 0.013 15.5 0.2 0.31 11.0 0.0 2.4 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region CarbpepA_inh PF02977.15 CAM43455.2 - 1.1 9.1 5.8 3.5 7.5 5.8 1.9 1 0 0 1 1 1 0 Carboxypeptidase A inhibitor FAA_hydrolase PF01557.18 CAM43456.1 - 1.4e-40 139.3 0.0 3.9e-39 134.6 0.0 2.0 1 1 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF3490 PF11995.8 CAM43456.1 - 0.014 15.2 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3490) HECT PF00632.25 CAM43457.1 - 1e-75 255.1 0.0 1.8e-75 254.3 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) FYVE PF01363.21 CAM43457.1 - 0.0067 16.5 6.4 0.038 14.1 6.4 2.4 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.21 CAM43457.1 - 0.1 12.8 6.5 0.34 11.2 6.5 1.9 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain CagS PF16707.5 CAM43458.1 - 0.019 15.0 0.1 0.039 14.0 0.1 1.5 1 0 0 1 1 1 0 Cag pathogenicity island protein S of Helicobacter pylori Nop53 PF07767.11 CAM43459.1 - 2.1e-15 57.0 17.4 6.7e-15 55.4 17.4 1.9 1 1 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF1053 PF06327.14 CAM43459.1 - 1.7 9.3 6.4 5.8 7.5 0.1 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) CtIP_N PF10482.9 CAM43460.2 - 0.45 10.6 12.7 0.17 11.9 8.5 2.4 1 1 1 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain SLX9 PF15341.6 CAM43460.2 - 0.56 10.6 3.2 1.6 9.1 3.2 1.7 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 DUF2229 PF09989.9 CAM43460.2 - 4.4 6.9 5.5 1.3 8.6 2.1 1.9 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) FAA_hydro_N_2 PF18288.1 CAM43460.2 - 5.7 7.4 8.6 0.26 11.8 0.9 2.9 3 0 0 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 Propep_M14 PF02244.16 CAM43461.1 - 0.15 12.5 0.1 0.43 11.0 0.1 1.7 1 0 0 1 1 1 0 Carboxypeptidase activation peptide SUR7 PF06687.12 CAM43464.1 - 0.002 17.8 3.8 0.002 17.8 3.8 1.6 2 0 0 2 2 2 1 SUR7/PalI family RRM_1 PF00076.22 CAM43465.1 - 3.3e-26 90.9 0.1 4e-14 52.2 0.0 3.5 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAM43465.1 - 6.4e-08 32.6 0.0 0.0097 16.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif RRM_Rrp7 PF17799.1 CAM43465.1 - 0.017 14.9 0.0 3.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain RRM_occluded PF16842.5 CAM43465.1 - 0.036 13.9 0.0 3.7 7.5 0.0 3.3 3 1 0 3 3 3 0 Occluded RNA-recognition motif FAD_binding_1 PF00667.20 CAM43466.2 - 1.4e-28 100.0 0.0 2.4e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CAM43466.2 - 3e-17 63.2 0.0 2.6e-12 47.2 0.0 2.5 2 0 0 2 2 2 2 Flavodoxin FAD_binding_6 PF00970.24 CAM43466.2 - 0.00063 20.1 0.0 0.0032 17.8 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CAM43466.2 - 0.034 14.8 0.1 0.17 12.5 0.0 2.2 1 1 1 2 2 2 0 Oxidoreductase NAD-binding domain DHHC PF01529.20 CAM43469.1 - 4.1e-26 91.7 12.5 4.1e-26 91.7 12.5 2.1 2 1 0 2 2 2 1 DHHC palmitoyltransferase Phage_holin_3_6 PF07332.11 CAM43469.1 - 0.014 15.4 1.2 0.014 15.4 1.2 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF1772 PF08592.11 CAM43469.1 - 0.33 11.3 7.8 0.13 12.6 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) CD47 PF04549.14 CAM43469.1 - 1.9 8.7 11.9 0.067 13.4 5.3 1.8 2 0 0 2 2 2 0 CD47 transmembrane region Retinal PF15449.6 CAM43470.1 - 1.2 6.8 20.6 1.4 6.6 20.6 1.2 1 0 0 1 1 1 0 Retinal protein NIF PF03031.18 CAM43471.1 - 9.5e-27 93.7 1.3 9.7e-27 93.7 0.2 1.5 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase DUF2868 PF11067.8 CAM43471.1 - 0.097 12.2 3.1 2.4 7.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) HNF-1_N PF04814.13 CAM43471.1 - 0.53 10.9 2.1 0.72 10.4 0.5 1.9 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus K_channel_TID PF07941.11 CAM43471.1 - 1.3 9.5 12.3 0.41 11.1 4.0 2.4 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DUF1180 PF06679.12 CAM43471.1 - 1.3 9.4 15.4 0.18 12.2 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) zf-HC5HC2H PF13771.6 CAM43472.1 - 1.5e-05 25.2 8.3 1.5e-05 25.2 8.3 2.4 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CAM43472.1 - 0.00055 20.1 10.0 0.00055 20.1 10.0 2.5 2 1 0 2 2 2 1 PHD-zinc-finger like domain TruD PF01142.18 CAM43473.1 - 0.011 14.7 0.0 0.47 9.2 0.0 2.2 2 0 0 2 2 2 0 tRNA pseudouridine synthase D (TruD) BST2 PF16716.5 CAM43474.2 - 0.014 16.0 3.9 0.014 16.0 3.9 2.5 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 RhoGEF67_u1 PF16615.5 CAM43474.2 - 0.13 12.7 0.4 0.13 12.7 0.4 4.9 4 1 1 5 5 5 0 Unstructured region one on RhoGEF 6 and 7 BTB_2 PF02214.22 CAM43475.1 - 4.4e-12 46.2 0.0 1.7e-11 44.3 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain TRAPPC9-Trs120 PF08626.11 CAM43476.1 - 8.2e-05 20.2 0.0 0.0022 15.5 0.0 2.6 3 0 0 3 3 3 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit SNARE PF05739.19 CAM43478.1 - 9.9e-12 44.7 0.2 3.2e-11 43.0 0.2 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 CAM43478.1 - 5.8e-06 26.1 17.3 8.8e-06 25.5 17.3 1.3 1 0 0 1 1 1 1 Syntaxin Syntaxin_2 PF14523.6 CAM43478.1 - 0.067 13.6 9.5 0.093 13.1 3.3 2.6 2 1 0 2 2 2 0 Syntaxin-like protein Lipoprotein_6 PF01441.19 CAM43478.1 - 0.18 11.8 2.3 0.58 10.1 0.6 2.2 2 0 0 2 2 2 0 Lipoprotein Acyl-CoA_dh_1 PF00441.24 CAM43480.1 - 3.6e-40 137.6 3.1 5.3e-40 137.1 3.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CAM43480.1 - 4.4e-27 94.1 0.7 9.1e-27 93.1 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CAM43480.1 - 3e-26 92.3 0.0 8.8e-26 90.8 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CAM43480.1 - 9.6e-21 74.5 0.1 1.7e-20 73.6 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 CAM43480.1 - 0.099 12.3 0.1 0.44 10.2 0.1 2.0 1 1 1 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal GalKase_gal_bdg PF10509.9 CAM43481.1 - 1.9e-14 52.9 0.0 6.7e-14 51.2 0.0 2.0 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 CAM43481.1 - 3.7e-08 33.6 0.2 1.4e-07 31.8 0.1 2.1 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 CAM43481.1 - 1.5e-06 28.3 0.1 3.2e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain MMR_HSR1 PF01926.23 CAM43483.1 - 1.2e-06 28.6 0.0 2.6e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CAM43483.1 - 0.0015 18.0 0.0 0.033 13.7 0.0 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B AAA_16 PF13191.6 CAM43483.1 - 0.0087 16.4 0.0 0.04 14.3 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CAM43483.1 - 0.084 13.2 0.1 5.4 7.3 0.1 2.6 1 1 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 CAM43483.1 - 0.097 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region IQ PF00612.27 CAM43484.1 - 8.3e-06 25.2 1.5 3.2e-05 23.3 1.5 2.1 1 0 0 1 1 1 1 IQ calmodulin-binding motif Dpy-30 PF05186.13 CAM43484.1 - 0.01 15.5 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 0 Dpy-30 motif MFS_1 PF07690.16 CAM43485.1 - 5.7e-25 88.0 40.7 2.9e-19 69.2 23.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5075 PF16825.5 CAM43486.1 - 0.0015 18.3 0.4 0.0024 17.6 0.4 1.3 1 0 0 1 1 1 1 IGP family C-type lectin domain DUF4492 PF14899.6 CAM43486.1 - 0.074 13.0 0.4 0.15 12.0 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) ATP-synt_8 PF00895.20 CAM43486.1 - 0.49 10.9 2.2 1.2 9.6 2.2 1.6 1 0 0 1 1 1 0 ATP synthase protein 8 UPF0370 PF13980.6 CAM43486.1 - 0.52 10.4 5.5 1 9.4 5.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) Abhydrolase_1 PF00561.20 CAM43487.1 - 9.1e-07 28.8 0.1 1.3e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CAM43487.1 - 1.4e-06 27.8 0.1 2.5e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF818 PF05677.12 CAM43487.1 - 9.4e-05 21.5 0.0 0.00012 21.2 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Peptidase_S9 PF00326.21 CAM43487.1 - 0.0014 18.2 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 CAM43487.1 - 0.022 15.3 0.5 0.058 14.0 0.1 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 CAM43487.1 - 0.025 14.5 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold LIDHydrolase PF10230.9 CAM43487.1 - 0.045 13.3 0.0 0.18 11.4 0.0 1.9 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase DUF676 PF05057.14 CAM43487.1 - 0.075 12.5 0.0 0.23 10.9 0.0 1.7 2 0 0 2 2 2 0 Putative serine esterase (DUF676) MFS_1 PF07690.16 CAM43488.1 - 6.2e-20 71.4 40.6 9.3e-18 64.3 18.5 2.5 2 2 1 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.7 CAM43488.1 - 1.2e-07 30.9 12.4 0.00038 19.4 4.2 3.1 2 1 1 3 3 3 2 MFS_1 like family Sugar_tr PF00083.24 CAM43488.1 - 3.8e-05 22.7 8.2 3.8e-05 22.7 8.2 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter DUF1614 PF07758.11 CAM43488.1 - 0.72 9.8 6.7 0.11 12.5 2.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1614) MFS_1 PF07690.16 CAM43489.1 - 9.2e-21 74.1 11.3 9.8e-21 74.1 11.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 CAM43489.1 - 5e-09 35.5 7.0 0.00091 18.2 0.0 2.1 1 1 1 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 CAM43489.1 - 8.9e-07 28.1 4.8 1.1e-06 27.9 4.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 CAM43489.1 - 0.0015 18.0 6.7 0.004 16.5 6.6 1.6 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1 PF07690.16 CAM43490.1 - 6.3e-25 87.8 34.9 1.3e-19 70.4 7.5 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CAM43490.1 - 1.1e-06 27.8 4.1 1.1e-06 27.8 4.1 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter Cytochrom_B_N_2 PF13631.6 CAM43490.1 - 0.19 11.7 3.8 4.9 7.1 0.3 2.6 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Aminotran_5 PF00266.19 CAM43492.1 - 1.2e-47 162.6 0.2 7.9e-32 110.6 0.1 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Leo1 PF04004.13 CAM43493.1 - 3.5e-11 43.2 0.7 8.4e-11 42.0 0.7 1.8 1 1 0 1 1 1 1 Leo1-like protein Alb1 PF09135.11 CAM43494.1 - 0.0023 18.8 12.7 0.0023 18.8 12.7 2.2 1 1 1 2 2 2 1 Alb1 PLC-beta_C PF08703.10 CAM43494.1 - 0.024 14.6 16.9 0.08 12.9 10.0 2.1 2 0 0 2 2 2 0 PLC-beta C terminal DIT1_PvcA PF05141.12 CAM43494.1 - 0.063 12.7 9.0 0.073 12.5 9.0 1.0 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein CARM1 PF11531.8 CAM43494.1 - 0.17 12.1 0.9 0.26 11.5 0.9 1.3 1 0 0 1 1 1 0 Coactivator-associated arginine methyltransferase 1 N terminal Exonuc_VII_L PF02601.15 CAM43494.1 - 8.5 5.8 12.2 9.6 5.7 12.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit MRP-S31 PF15433.6 CAM43494.1 - 9.3 5.8 14.3 11 5.6 14.3 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Pkinase PF00069.25 CAM43495.2 - 2.3e-07 30.4 0.0 0.00023 20.6 0.0 2.9 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM43495.2 - 5.2e-05 22.7 0.0 0.00044 19.6 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Gp_dh_C PF02800.20 CAM43495.2 - 0.015 14.9 0.1 0.14 11.7 0.1 2.3 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain VWA_2 PF13519.6 CAM43495.2 - 0.15 12.7 0.0 0.44 11.2 0.0 1.7 1 0 0 1 1 1 0 von Willebrand factor type A domain Sybindin PF04099.12 CAM43496.1 - 2.9e-17 62.9 0.1 3.3e-17 62.7 0.1 1.0 1 0 0 1 1 1 1 Sybindin-like family CHU_C PF13585.6 CAM43496.1 - 0.039 14.0 0.1 0.063 13.3 0.1 1.4 1 0 0 1 1 1 0 C-terminal domain of CHU protein family Tmpp129 PF10272.9 CAM43496.1 - 0.04 13.2 0.0 0.041 13.2 0.0 1.1 1 0 0 1 1 1 0 Putative transmembrane protein precursor SpoU_methylase PF00588.19 CAM43497.1 - 2.1e-07 31.2 0.0 6.1e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 SpoU rRNA Methylase family OrfB_IS605 PF01385.19 CAM43497.1 - 4.5 7.5 6.4 2.3 8.5 3.0 2.2 2 1 0 2 2 2 0 Probable transposase SRAP PF02586.14 CAM43498.1 - 0.079 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 SOS response associated peptidase (SRAP) Tctex-1 PF03645.13 CAM43499.1 - 3.1e-27 94.8 0.1 3.5e-27 94.6 0.1 1.0 1 0 0 1 1 1 1 Tctex-1 family DSPc PF00782.20 CAM43499.1 - 0.016 15.0 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain TOC159_MAD PF11886.8 CAM43499.1 - 0.13 11.2 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Translocase of chloroplast 159/132, membrane anchor domain DUF4200 PF13863.6 CAM43500.1 - 0.0076 16.6 6.4 0.02 15.3 6.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) Not3 PF04065.15 CAM43500.1 - 0.016 14.7 2.6 0.027 13.9 2.6 1.3 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component TMF_DNA_bd PF12329.8 CAM43500.1 - 0.022 14.8 1.3 0.044 13.8 1.3 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF641 PF04859.12 CAM43500.1 - 0.034 14.5 1.1 0.23 11.8 1.4 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) FAM184 PF15665.5 CAM43500.1 - 0.25 11.1 6.9 0.6 9.8 6.9 1.7 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B DUF2968 PF11180.8 CAM43500.1 - 0.57 9.8 11.5 1.7 8.2 11.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Uso1_p115_C PF04871.13 CAM43500.1 - 0.82 10.0 5.0 2.1 8.7 5.0 1.7 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region PRKG1_interact PF15898.5 CAM43500.1 - 0.96 10.4 5.5 21 6.1 4.3 2.9 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain UPF0182 PF03699.13 CAM43501.1 - 1.3 7.1 4.8 2.3 6.2 4.8 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0182) Cupin_8 PF13621.6 CAM43502.1 - 1e-44 153.2 0.0 2e-44 152.2 0.0 1.4 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.14 CAM43502.1 - 5.1e-16 59.2 0.0 2.7e-09 37.3 0.0 3.0 2 1 0 2 2 2 2 Leucine carboxyl methyltransferase Kelch_5 PF13854.6 CAM43502.1 - 1.4e-08 34.5 0.2 0.48 10.5 0.0 5.4 5 0 0 5 5 5 2 Kelch motif Cupin_4 PF08007.12 CAM43502.1 - 0.0003 20.4 0.0 0.00075 19.1 0.0 1.5 1 1 0 1 1 1 1 Cupin superfamily protein Kelch_4 PF13418.6 CAM43502.1 - 0.00086 19.3 4.6 0.28 11.2 0.0 5.0 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_3 PF13415.6 CAM43502.1 - 0.019 15.3 6.5 1.6 9.1 0.0 4.5 5 0 0 5 5 5 0 Galactose oxidase, central domain PPR_2 PF13041.6 CAM43503.1 - 1.1e-21 76.7 10.7 4.5e-07 30.0 0.0 9.0 6 1 4 10 10 10 7 PPR repeat family PPR PF01535.20 CAM43503.1 - 5.5e-21 73.3 31.7 0.014 15.6 0.0 12.4 16 0 0 16 16 16 6 PPR repeat PPR_3 PF13812.6 CAM43503.1 - 2.4e-14 53.2 9.7 0.007 16.4 0.1 7.8 5 1 4 9 9 9 6 Pentatricopeptide repeat domain PPR_1 PF12854.7 CAM43503.1 - 4.3e-10 39.1 0.3 0.41 10.4 0.0 6.4 6 0 0 6 6 6 3 PPR repeat PPR_long PF17177.4 CAM43503.1 - 4.9e-06 26.1 14.9 2.8e-05 23.6 0.6 5.8 3 1 3 6 6 6 2 Pentacotripeptide-repeat region of PRORP RNA_pol_Rpb4 PF03874.16 CAM43503.1 - 0.22 11.8 1.0 75 3.7 0.0 4.3 4 2 0 4 4 4 0 RNA polymerase Rpb4 SPOB_a PF14689.6 CAM43503.1 - 1 9.1 4.9 51 3.7 0.1 5.0 6 0 0 6 6 6 0 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_19 PF14559.6 CAM43503.1 - 5.8 7.5 7.9 22 5.6 0.0 4.8 6 1 0 6 6 6 0 Tetratricopeptide repeat DENN PF02141.21 CAM43504.1 - 8.7e-23 81.2 0.5 1.6e-22 80.3 0.5 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain TPR_14 PF13428.6 CAM43505.1 - 0.066 14.1 1.8 0.57 11.1 0.2 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CAM43505.1 - 0.089 13.0 1.1 0.17 12.1 1.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3837 PF12939.7 CAM43505.1 - 0.1 13.0 0.1 0.34 11.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3837) TPR_2 PF07719.17 CAM43505.1 - 0.29 11.4 2.8 24 5.4 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 CAM43505.1 - 0.3 11.6 1.9 1.1 9.8 0.3 2.5 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 CAM43505.1 - 1.1 10.0 4.5 0.85 10.3 1.9 2.2 2 1 1 3 3 3 0 Tetratricopeptide repeat DnaJ_C PF01556.18 CAM43506.1 - 2.6e-31 108.7 0.0 3.5e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CAM43506.1 - 1.4e-21 76.3 0.9 3e-21 75.3 0.9 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CAM43506.1 - 3.4e-15 56.2 19.4 6.7e-15 55.2 19.4 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 CAM43506.1 - 0.023 14.7 7.5 0.37 10.8 1.0 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 CAM43506.1 - 0.038 14.0 17.1 0.034 14.1 5.4 3.0 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein DNA_pol_A_exo1 PF01612.20 CAM43507.1 - 1.8e-15 57.1 0.0 2.6e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease zf-C2H2_10 PF16588.5 CAM43507.1 - 0.0018 18.0 10.1 0.0058 16.3 2.1 4.1 5 0 0 5 5 5 3 C2H2 zinc-finger zf-CCHC PF00098.23 CAM43507.1 - 0.0032 17.5 1.4 0.0032 17.5 1.4 5.2 5 1 0 5 5 5 3 Zinc knuckle REV1_C PF16727.5 CAM43507.1 - 0.056 13.8 0.6 0.7 10.3 0.0 2.6 3 1 0 3 3 3 0 DNA repair protein REV1 C-terminal domain Glyoxalase PF00903.25 CAM43509.1 - 1e-15 58.0 0.2 1.3e-15 57.7 0.2 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 CAM43509.1 - 3e-09 37.1 0.0 4.5e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 CAM43509.1 - 0.0054 16.7 0.0 0.011 15.6 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase-like domain CppA_N PF14506.6 CAM43509.1 - 0.033 14.3 0.0 0.042 13.9 0.0 1.3 1 1 0 1 1 1 0 CppA N-terminal Glyoxalase_3 PF13468.6 CAM43509.1 - 0.038 14.1 0.0 4.3 7.4 0.0 2.6 1 1 1 2 2 2 0 Glyoxalase-like domain PAF-AH_p_II PF03403.13 CAM43510.1 - 6.7e-28 97.3 0.0 4.1e-27 94.7 0.0 1.9 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.7 CAM43510.1 - 1.1e-05 26.2 0.6 4.8e-05 24.1 0.3 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 CAM43510.1 - 3.8e-05 22.7 0.0 0.00013 20.9 0.0 1.8 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 CAM43510.1 - 0.0036 16.6 0.1 2.4 7.3 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CAM43510.1 - 0.0093 15.6 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 CAM43510.1 - 0.15 12.0 0.0 0.36 10.7 0.0 1.6 2 0 0 2 2 2 0 Lipase (class 3) Ser_hydrolase PF06821.13 CAM43510.1 - 0.16 11.9 0.1 0.62 9.9 0.0 2.0 2 1 1 3 3 3 0 Serine hydrolase ICMT PF04140.14 CAM43511.1 - 1.3e-19 70.4 1.3 1.3e-19 70.4 1.3 2.0 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CAM43511.1 - 2e-07 31.3 1.9 2e-07 31.3 1.9 3.1 3 2 1 4 4 4 1 Phospholipid methyltransferase DUF1295 PF06966.12 CAM43511.1 - 0.0017 17.9 2.2 0.0017 17.9 2.2 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) DUF2721 PF11026.8 CAM43511.1 - 0.0098 15.8 0.2 0.0098 15.8 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2721) OST3_OST6 PF04756.13 CAM43511.1 - 0.04 13.3 0.0 0.074 12.4 0.0 1.4 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family RseC_MucC PF04246.12 CAM43511.1 - 0.49 10.4 2.6 0.43 10.5 0.1 2.0 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC p12I PF12233.8 CAM43511.1 - 1.4 9.4 6.2 0.18 12.4 1.5 1.9 2 0 0 2 2 2 0 Human adult T cell leukemia/lymphoma virus protein NDUFA12 PF05071.16 CAM43512.1 - 6.5e-05 23.7 1.1 6.5e-05 23.7 1.1 2.1 2 1 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 zf-CCHC_2 PF13696.6 CAM43513.1 - 9.8e-08 31.7 8.2 9.8e-08 31.7 8.2 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-RING_4 PF14570.6 CAM43513.1 - 0.0019 18.0 1.3 0.0019 18.0 1.3 1.8 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-CCHC PF00098.23 CAM43513.1 - 0.081 13.0 4.5 0.23 11.6 4.5 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-RING_5 PF14634.6 CAM43513.1 - 0.85 9.6 9.5 0.51 10.3 3.7 2.4 2 0 0 2 2 2 0 zinc-RING finger domain FYVE PF01363.21 CAM43513.1 - 1.2 9.3 6.9 0.18 12.0 1.8 2.1 2 0 0 2 2 2 0 FYVE zinc finger DUF4428 PF14471.6 CAM43513.1 - 1.3 9.0 5.0 34 4.5 0.1 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4428) DZR PF12773.7 CAM43513.1 - 2.8 8.1 7.0 3.3 7.8 2.0 2.5 2 0 0 2 2 2 0 Double zinc ribbon TF_Zn_Ribbon PF08271.12 CAM43513.1 - 4 7.0 8.1 1.9 8.1 2.6 2.8 2 1 0 2 2 2 0 TFIIB zinc-binding ThiF PF00899.21 CAM43514.1 - 1.1e-73 247.6 0.0 3.2e-57 193.7 0.0 2.3 1 1 1 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 CAM43514.1 - 1e-56 192.7 0.1 1.5e-56 192.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_4HB PF16191.5 CAM43514.1 - 1.6e-11 44.2 0.0 3.1e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Rhamno_transf PF11316.8 CAM43514.1 - 0.051 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative rhamnosyl transferase Lipocalin_9 PF17186.4 CAM43515.1 - 9.2e-08 32.4 0.4 4.3e-07 30.3 0.0 2.4 3 0 0 3 3 3 1 Lipocalin-like domain FGGY_N PF00370.21 CAM43516.1 - 1.1e-68 231.4 0.0 1.5e-68 231.0 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 CAM43516.1 - 1.2e-58 198.1 0.7 2.6e-58 197.0 0.7 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DnaJ PF00226.31 CAM43517.1 - 9.2e-10 38.5 0.0 2.1e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Babuvirus_MP PF07234.11 CAM43517.1 - 0.066 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Movement and RNA silencing protein DEAD PF00270.29 CAM43518.1 - 1.3e-42 145.6 0.0 2.4e-41 141.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAM43518.1 - 5.5e-31 107.2 0.1 1.3e-30 106.0 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAM43518.1 - 0.00045 20.3 0.0 0.0011 19.0 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CAM43518.1 - 0.013 14.7 0.1 0.023 13.9 0.1 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 CAM43518.1 - 0.049 13.9 0.6 0.51 10.6 0.6 2.4 1 1 0 1 1 1 0 AAA domain Nup160 PF11715.8 CAM43520.1 - 0.0044 15.7 0.0 0.31 9.6 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 EF-hand_7 PF13499.6 CAM43520.1 - 0.19 12.2 0.0 0.45 11.0 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair Dynein_light PF01221.18 CAM43521.1 - 1e-13 51.4 0.2 1.4e-13 51.0 0.2 1.3 1 1 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.18 CAM43521.1 - 0.067 13.9 0.0 0.097 13.3 0.0 1.4 1 0 0 1 1 1 0 Ground-like domain IPK PF03770.16 CAM43522.1 - 1.7e-22 80.2 0.0 2.3e-21 76.6 0.0 2.2 1 1 0 1 1 1 1 Inositol polyphosphate kinase Flavokinase PF01687.17 CAM43524.1 - 5.1e-25 87.9 0.0 5.9e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Pkinase PF00069.25 CAM43525.2 - 5.8e-37 127.5 0.0 1.3e-36 126.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM43525.2 - 2e-15 56.8 0.0 9.7e-12 44.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CAM43525.2 - 6.4e-07 29.5 0.7 1.2e-05 25.4 0.0 2.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CAM43525.2 - 2.4e-06 26.6 0.0 9.1e-06 24.7 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 CAM43525.2 - 0.032 13.8 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 RIO1 family TPR_14 PF13428.6 CAM43525.2 - 0.11 13.3 1.4 0.46 11.4 1.4 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat RPN7 PF10602.9 CAM43525.2 - 0.13 12.0 0.1 0.24 11.1 0.1 1.3 1 0 0 1 1 1 0 26S proteasome subunit RPN7 TPR_16 PF13432.6 CAM43525.2 - 5.1 7.8 7.0 0.33 11.6 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat His_Phos_1 PF00300.22 CAM43527.1 - 7.1e-11 42.2 0.0 1.6e-09 37.7 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) RRM_1 PF00076.22 CAM43528.1 - 3.9e-07 29.8 0.0 8.9e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_13 PF17958.1 CAM43529.1 - 4e-17 61.8 0.0 7.3e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 CAM43529.1 - 3.6e-12 46.6 0.0 1.8e-11 44.3 0.0 2.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CAM43529.1 - 0.0066 16.3 1.3 0.019 14.9 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 CAM43529.1 - 0.012 15.5 2.4 2.9 7.8 0.2 2.7 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 CAM43529.1 - 0.026 14.0 4.1 0.11 12.1 0.2 3.3 3 0 0 3 3 3 0 EF hand EF-hand_5 PF13202.6 CAM43529.1 - 0.16 11.6 0.5 0.56 9.8 0.0 2.2 2 0 0 2 2 2 0 EF hand Cys_Met_Meta_PP PF01053.20 CAM43531.1 - 3.3e-128 427.5 0.1 3.7e-128 427.3 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 CAM43531.1 - 2.9e-09 36.7 1.2 1.5e-08 34.4 0.2 2.0 1 1 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 CAM43531.1 - 0.00015 20.9 0.1 0.00035 19.7 0.1 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CAM43531.1 - 0.0025 17.2 0.5 0.0062 15.8 0.5 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase DUF3586 PF12131.8 CAM43531.1 - 0.47 10.7 4.5 0.36 11.1 2.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3586) AAA PF00004.29 CAM43533.1 - 1.7e-15 57.6 0.0 3.4e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 CAM43533.1 - 2.2e-13 50.4 0.0 6.4e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 CAM43533.1 - 3.2e-11 43.3 0.0 1.7e-10 40.9 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 CAM43533.1 - 1.2e-10 41.6 0.0 2.1e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 CAM43533.1 - 2e-07 30.9 0.1 1.7e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CAM43533.1 - 7.6e-06 26.3 0.0 1.8e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CAM43533.1 - 7.6e-06 26.4 0.0 2.9e-05 24.5 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 CAM43533.1 - 1.1e-05 24.9 0.0 1.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 CAM43533.1 - 1.6e-05 25.2 0.5 0.00021 21.6 0.3 2.6 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 CAM43533.1 - 1.9e-05 24.7 0.0 6e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 CAM43533.1 - 3.8e-05 23.7 0.0 6.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CAM43533.1 - 7.2e-05 22.7 0.1 0.0037 17.1 0.0 2.4 1 1 1 2 2 2 1 AAA domain TniB PF05621.11 CAM43533.1 - 0.00014 21.3 0.0 0.0032 16.9 0.0 2.2 2 0 0 2 2 2 1 Bacterial TniB protein AAA_24 PF13479.6 CAM43533.1 - 0.00025 20.9 0.0 0.00045 20.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 CAM43533.1 - 0.00042 20.9 0.0 0.00057 20.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CAM43533.1 - 0.00081 19.2 0.0 0.0022 17.8 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 CAM43533.1 - 0.0013 19.0 0.0 0.0053 17.1 0.0 2.1 2 0 0 2 2 1 1 AAA C-terminal domain AAA_29 PF13555.6 CAM43533.1 - 0.0021 17.7 0.0 0.005 16.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATPase_2 PF01637.18 CAM43533.1 - 0.0021 18.0 0.0 0.004 17.1 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_3 PF07726.11 CAM43533.1 - 0.0025 17.6 0.0 0.022 14.6 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 CAM43533.1 - 0.0047 16.1 0.0 0.0077 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 CAM43533.1 - 0.0055 16.2 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region NB-ARC PF00931.22 CAM43533.1 - 0.022 13.9 0.0 2.6 7.1 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Sigma54_activat PF00158.26 CAM43533.1 - 0.026 14.2 0.0 0.14 11.9 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 CAM43533.1 - 0.03 14.1 0.0 2.6 7.7 0.0 2.6 3 0 0 3 3 3 0 IstB-like ATP binding protein ResIII PF04851.15 CAM43533.1 - 0.03 14.3 0.0 1 9.4 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit MeaB PF03308.16 CAM43533.1 - 0.036 13.1 0.1 0.084 11.8 0.1 1.6 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 CAM43533.1 - 0.038 14.2 0.1 0.084 13.0 0.1 1.7 2 1 0 2 2 1 0 AAA domain DEAD PF00270.29 CAM43533.1 - 0.04 13.7 0.2 0.33 10.7 0.0 2.0 1 1 1 2 2 2 0 DEAD/DEAH box helicase DSBA PF01323.20 CAM43533.1 - 0.05 13.4 0.1 0.12 12.2 0.0 1.6 2 0 0 2 2 2 0 DSBA-like thioredoxin domain DUF2075 PF09848.9 CAM43533.1 - 0.063 12.5 0.0 0.099 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 CAM43533.1 - 0.092 13.3 0.0 0.18 12.3 0.0 1.6 1 1 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.18 CAM43533.1 - 0.12 11.7 0.0 0.29 10.5 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Pex19 PF04614.12 CAM43534.1 - 1.4e-14 54.5 0.3 1.4e-14 54.5 0.3 3.4 1 1 1 3 3 3 3 Pex19 protein family PPR_2 PF13041.6 CAM43534.1 - 0.092 13.0 0.1 0.092 13.0 0.1 2.2 3 0 0 3 3 3 0 PPR repeat family Macoilin PF09726.9 CAM43535.1 - 0.33 9.5 14.2 0.41 9.1 14.2 1.1 1 0 0 1 1 1 0 Macoilin family DUF4551 PF15087.6 CAM43535.1 - 5.2 5.8 11.9 6.2 5.5 11.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) GREB1 PF15782.5 CAM43535.1 - 9.6 3.2 10.7 11 3.0 10.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ribosomal_L31e PF01198.19 CAM43536.1 - 5.8e-26 90.6 1.7 2.1e-25 88.7 0.3 2.2 1 1 1 2 2 2 1 Ribosomal protein L31e Ribosomal_L31e PF01198.19 CAM43537.1 - 5.8e-26 90.6 1.7 2.1e-25 88.7 0.3 2.2 1 1 1 2 2 2 1 Ribosomal protein L31e WD40 PF00400.32 CAM43538.1 - 1.9e-06 28.5 12.2 0.0075 17.1 1.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat LRR_9 PF14580.6 CAM43539.1 - 1.3e-10 41.1 0.3 3e-10 39.9 0.3 1.6 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CAM43539.1 - 2e-09 37.6 3.0 9.7e-06 25.8 1.6 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM43539.1 - 1.5e-07 31.1 7.1 0.00019 21.1 0.3 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 CAM43539.1 - 8.3e-05 22.3 5.4 1.6 9.0 0.1 4.0 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 CAM43539.1 - 0.047 14.2 1.9 1.4 9.8 0.0 3.5 2 1 0 2 2 2 0 Leucine Rich Repeat TRAPP PF04051.16 CAM43540.1 - 2.6e-24 85.6 0.0 3e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Mito_carr PF00153.27 CAM43541.1 - 3.1e-52 174.5 0.2 1.9e-18 66.2 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Complex1_LYR_1 PF13232.6 CAM43541.1 - 0.17 12.5 0.0 0.42 11.2 0.0 1.7 1 0 0 1 1 1 0 Complex1_LYR-like 6PGD PF00393.19 CAM43542.1 - 2.1e-75 253.8 0.0 4e-75 252.9 0.0 1.4 2 0 0 2 2 2 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 CAM43542.1 - 6.8e-46 156.3 0.1 1.4e-45 155.3 0.0 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 CAM43542.1 - 6.8e-05 23.0 0.1 0.00019 21.5 0.0 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 CAM43542.1 - 0.00041 20.3 0.0 0.00066 19.6 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 CAM43542.1 - 0.006 17.1 0.1 0.014 16.0 0.1 1.7 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 CAM43542.1 - 0.0074 15.7 0.1 0.014 14.8 0.1 1.6 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RuvA_C PF07499.13 CAM43542.1 - 0.02 15.3 0.0 0.046 14.2 0.0 1.6 1 0 0 1 1 1 0 RuvA, C-terminal domain NAD_Gly3P_dh_N PF01210.23 CAM43542.1 - 0.029 14.4 0.0 0.068 13.1 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Git3 PF11710.8 CAM43542.1 - 0.071 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 TP_methylase PF00590.20 CAM43543.1 - 4.5e-20 72.5 1.0 1.5e-19 70.8 0.3 2.2 2 1 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF2428 PF10350.9 CAM43544.2 - 3.7e-33 115.0 0.2 1.1e-32 113.4 0.2 1.9 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 CAM43544.2 - 0.043 14.1 10.4 11 6.6 0.5 6.2 4 0 0 4 4 4 0 HEAT repeat PARP_regulatory PF01358.18 CAM43546.1 - 8e-13 48.0 0.0 5.3e-08 32.1 0.0 2.6 2 1 0 2 2 2 2 Poly A polymerase regulatory subunit CDC50 PF03381.15 CAM43548.1 - 1.1e-72 244.9 0.0 1.4e-72 244.5 0.0 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF3185 PF11381.8 CAM43548.1 - 0.13 12.3 0.4 0.24 11.4 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) TOH_N PF12549.8 CAM43550.1 - 0.055 13.3 0.4 0.15 12.0 0.4 1.8 1 0 0 1 1 1 0 Tyrosine hydroxylase N terminal Rep_fac-A_3 PF08661.11 CAM43552.1 - 2.2e-07 31.2 0.0 3.9e-07 30.4 0.0 1.4 1 1 0 1 1 1 1 Replication factor A protein 3 Rad4 PF03835.15 CAM43553.2 - 2.7e-20 72.5 0.1 6.9e-20 71.2 0.1 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 CAM43553.2 - 9.1e-15 54.8 0.0 3e-14 53.2 0.0 1.9 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 CAM43553.2 - 1.4e-08 34.4 0.0 3e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 CAM43553.2 - 0.005 17.8 1.3 1.1 10.3 0.4 3.8 2 1 0 2 2 2 1 Rad4 beta-hairpin domain 2 Acyl_transf_1 PF00698.21 CAM43555.1 - 2.6e-22 79.7 0.0 9.1e-22 78.0 0.0 1.9 2 1 0 2 2 2 1 Acyl transferase domain MFS_1_like PF12832.7 CAM43556.1 - 2.9e-22 79.1 9.4 3.7e-22 78.7 9.4 1.0 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 CAM43556.1 - 0.00012 21.1 17.1 0.00012 21.1 17.1 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4271 PF14093.6 CAM43556.1 - 0.023 14.6 0.2 0.023 14.6 0.2 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4271) SNARE PF05739.19 CAM43557.1 - 3e-05 23.9 0.3 6.9e-05 22.8 0.3 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 CAM43557.1 - 0.31 11.4 10.6 0.044 14.2 3.2 2.4 2 0 0 2 2 2 0 Syntaxin-like protein DUF3328 PF11807.8 CAM43558.2 - 0.085 12.6 4.0 2.7 7.7 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3328) ThylakoidFormat PF11264.8 CAM43559.1 - 0.012 15.3 1.5 0.032 13.9 1.5 1.7 1 0 0 1 1 1 0 Thylakoid formation protein FYVE PF01363.21 CAM43560.1 - 1.6e-18 66.6 7.0 2.4e-18 66.0 7.0 1.3 1 0 0 1 1 1 1 FYVE zinc finger OrfB_Zn_ribbon PF07282.11 CAM43560.1 - 2.5 8.1 6.4 6.1 6.8 6.4 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain SMC_N PF02463.19 CAM43561.1 - 5e-57 192.9 0.0 1.2e-55 188.4 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CAM43561.1 - 3.1e-23 82.3 0.0 3.1e-23 82.3 0.0 2.6 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CAM43561.1 - 6.5e-15 55.7 0.0 9.1e-07 29.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CAM43561.1 - 4.5e-14 53.4 0.0 4.5e-14 53.4 0.0 4.8 2 1 1 3 3 3 1 AAA domain AAA_15 PF13175.6 CAM43561.1 - 5.9e-09 36.1 0.0 5.9e-09 36.1 0.0 2.4 3 1 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 CAM43561.1 - 1.2e-06 28.1 0.0 2.6e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CAM43561.1 - 0.029 14.3 0.2 0.34 10.8 0.0 3.0 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 CAM43561.1 - 0.064 13.5 5.5 7.3 6.9 0.0 4.4 3 2 0 3 3 3 0 AAA domain ABC_tran PF00005.27 CAM43561.1 - 0.085 13.4 0.0 0.085 13.4 0.0 5.2 4 2 1 5 5 5 0 ABC transporter FlaC_arch PF05377.11 CAM43561.1 - 0.56 10.7 12.5 55 4.3 0.6 6.2 5 1 1 6 6 6 0 Flagella accessory protein C (FlaC) NIF PF03031.18 CAM43562.2 - 8.2e-30 103.6 0.0 3.1e-15 56.3 0.0 2.3 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase KH_1 PF00013.29 CAM43564.1 - 0.00047 19.9 0.4 0.0012 18.6 0.4 1.7 1 0 0 1 1 1 1 KH domain DUF2497 PF10691.9 CAM43565.1 - 0.01 16.2 3.2 0.014 15.8 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2497) Fib_alpha PF08702.10 CAM43565.1 - 0.029 14.5 6.7 1.2 9.4 0.3 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1043 PF06295.12 CAM43565.1 - 0.061 13.3 7.0 0.12 12.4 0.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) Baculo_PEP_C PF04513.12 CAM43565.1 - 0.064 13.3 4.1 0.81 9.7 0.7 2.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 CAM43565.1 - 0.23 11.3 29.9 0.86 9.5 29.1 2.3 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain zf-C4H2 PF10146.9 CAM43565.1 - 0.47 10.7 10.1 0.15 12.3 0.3 2.5 1 1 1 2 2 2 0 Zinc finger-containing protein BshC PF10079.9 CAM43565.1 - 2.3 6.9 8.6 0.43 9.3 4.4 1.7 1 1 1 2 2 2 0 Bacillithiol biosynthesis BshC Exonuc_VII_L PF02601.15 CAM43565.1 - 3.9 7.0 16.8 15 5.0 16.8 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit Gp58 PF07902.11 CAM43565.1 - 5.5 5.1 7.1 11 4.2 7.1 1.4 1 0 0 1 1 1 0 gp58-like protein Allexi_40kDa PF05549.11 CAM43565.1 - 7.2 6.0 6.3 3 7.3 1.8 2.3 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF948 PF06103.11 CAM43565.1 - 8.7 6.7 7.0 52 4.2 0.0 4.2 3 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 CAM43565.1 - 9 6.4 12.3 2.8 8.0 1.4 3.4 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) CRAL_TRIO PF00650.20 CAM43566.1 - 3.9e-26 91.7 0.0 5.9e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CAM43566.1 - 3.4e-05 23.9 0.5 7.8e-05 22.8 0.5 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain FUSC_2 PF13515.6 CAM43570.1 - 1.3e-07 31.8 5.6 1.3e-07 31.8 5.6 2.5 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 CAM43570.1 - 6.9 5.1 10.1 1 7.8 5.8 1.7 2 0 0 2 2 2 0 Fusaric acid resistance protein family XPG_I_2 PF12813.7 CAM43572.2 - 9.1e-37 126.9 0.0 1.5e-36 126.2 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.18 CAM43572.2 - 1.4e-20 73.5 0.1 3.1e-20 72.3 0.1 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 CAM43572.2 - 1.9e-19 70.0 0.0 3.8e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain Methyltransf_23 PF13489.6 CAM43573.1 - 4e-25 88.5 0.0 5.6e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAM43573.1 - 0.00052 20.7 0.0 0.0039 17.9 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAM43573.1 - 0.0065 17.1 0.0 0.96 10.1 0.0 2.9 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAM43573.1 - 0.03 15.0 0.0 0.18 12.5 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Pro_isomerase PF00160.21 CAM43574.1 - 2.1e-28 99.6 0.0 4.2e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NifU_N PF01592.16 CAM43575.1 - 6.7e-50 168.5 0.0 8.7e-50 168.2 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain MatE PF01554.18 CAM43576.1 - 3.7e-33 114.4 27.8 3.7e-17 62.5 9.7 3.2 3 0 0 3 3 3 3 MatE DUF5510 PF17629.2 CAM43576.1 - 0.31 11.0 3.6 2.9 7.9 0.7 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5510) MatE PF01554.18 CAM43577.1 - 4.9e-32 110.8 29.2 9e-16 57.9 11.2 3.3 3 0 0 3 3 3 3 MatE DUF5510 PF17629.2 CAM43577.1 - 0.22 11.5 3.6 2.6 8.0 0.8 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5510) Rho_RNA_bind PF07497.12 CAM43580.1 - 0.028 14.3 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 Rho termination factor, RNA-binding domain NDUF_B7 PF05676.13 CAM43581.1 - 5.2e-09 35.7 0.5 8.8e-09 35.0 0.5 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Ribul_P_3_epim PF00834.19 CAM43583.1 - 1.3e-51 174.9 0.0 1.5e-51 174.6 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family LRV PF01816.17 CAM43583.1 - 0.0034 17.7 0.5 0.0085 16.4 0.5 1.6 1 0 0 1 1 1 1 Leucine rich repeat variant PEX11 PF05648.14 CAM43584.1 - 5.2e-09 35.9 0.0 6.5e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PEX11 PF05648.14 CAM43585.1 - 5.8e-15 55.4 0.0 1.3e-14 54.2 0.0 1.5 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) LPD23 PF18838.1 CAM43587.1 - 0.25 11.1 1.5 0.93 9.3 0.1 2.7 3 0 0 3 3 3 0 Large polyvalent protein associated domain 23 GTP-bdg_M PF16360.5 CAM43587.1 - 0.68 10.6 0.1 0.68 10.6 0.1 4.7 4 1 1 5 5 5 0 GTP-binding GTPase Middle Region APC_N_CC PF16689.5 CAM43587.1 - 4.4 7.4 9.2 0.72 10.0 0.1 3.7 4 0 0 4 4 4 0 Coiled-coil N-terminus of APC, dimerisation domain Cullin PF00888.22 CAM43590.1 - 1.3e-15 57.1 0.0 2.1e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Cullin family Antibiotic_NAT PF02522.14 CAM43590.1 - 0.013 15.3 0.0 0.039 13.8 0.0 1.8 2 0 0 2 2 2 0 Aminoglycoside 3-N-acetyltransferase Ribosomal_L27A PF00828.19 CAM43591.1 - 5.4e-21 75.6 0.3 6.9e-21 75.3 0.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L27A PF00828.19 CAM43593.1 - 5.4e-21 75.6 0.3 6.9e-21 75.3 0.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L14 PF00238.19 CAM43594.1 - 4.8e-37 126.8 0.0 5.7e-37 126.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ribosomal_L14 PF00238.19 CAM43595.1 - 4.8e-37 126.8 0.0 5.7e-37 126.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Cep57_CLD_2 PF14197.6 CAM43597.1 - 0.0081 16.2 3.1 0.0081 16.2 3.1 3.6 3 0 0 3 3 3 1 Centrosome localisation domain of PPC89 CLZ PF16526.5 CAM43597.1 - 0.3 11.5 8.8 1.9 8.9 0.3 3.7 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CENP-F_leu_zip PF10473.9 CAM43597.1 - 1.2 9.1 12.1 4.1 7.4 2.8 3.0 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BRE1 PF08647.11 CAM43597.1 - 1.4 9.0 6.6 1 9.4 0.2 3.0 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase TSC22 PF01166.18 CAM43597.1 - 8.4 6.8 7.4 10 6.5 0.4 3.8 4 1 0 4 4 4 0 TSC-22/dip/bun family SET PF00856.28 CAM43598.1 - 1.6e-05 25.4 0.0 2.4e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 SET domain Proteasome PF00227.26 CAM43599.1 - 4.1e-48 163.4 0.5 4.9e-48 163.1 0.5 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 CAM43599.1 - 0.0026 17.1 0.2 0.0026 17.1 0.2 2.3 2 0 0 2 2 2 1 Proteasome beta subunits C terminal sCache_2 PF17200.4 CAM43599.1 - 0.045 13.6 0.1 0.077 12.8 0.1 1.3 1 0 0 1 1 1 0 Single Cache domain 2 Cobalamin_bind PF01122.19 CAM43599.1 - 0.069 12.0 0.2 0.24 10.3 0.0 1.7 2 0 0 2 2 2 0 Eukaryotic cobalamin-binding protein Ribosomal_S17 PF00366.20 CAM43600.1 - 9.4e-19 67.3 0.6 1.8e-18 66.4 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 Cpn60_TCP1 PF00118.24 CAM43601.1 - 2.7e-155 517.7 2.1 3.5e-155 517.4 2.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NDK PF00334.19 CAM43602.1 - 7.4e-31 107.0 0.0 5e-28 97.8 0.0 2.3 2 0 0 2 2 2 2 Nucleoside diphosphate kinase DUF1126 PF06565.12 CAM43602.1 - 6e-06 26.0 0.0 2e-05 24.4 0.1 1.9 2 0 0 2 2 2 1 DUF1126 PH-like domain DUF371 PF04027.13 CAM43602.1 - 0.13 12.2 0.4 2.5 8.1 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF371) WD40 PF00400.32 CAM43603.1 - 9.1e-29 99.1 16.4 2.8e-08 34.3 0.0 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat Sof1 PF04158.14 CAM43603.1 - 1.3e-09 38.2 7.6 2.2e-09 37.4 7.6 1.4 1 0 0 1 1 1 1 Sof1-like domain ANAPC4_WD40 PF12894.7 CAM43603.1 - 7e-05 23.0 0.1 0.12 12.7 0.0 4.2 2 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CAM43603.1 - 0.00037 19.6 0.3 2 7.3 0.0 3.5 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CAM43603.1 - 0.0014 18.6 0.1 0.0037 17.2 0.1 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CAM43603.1 - 0.0014 18.0 0.0 0.5 9.6 0.0 3.0 3 0 0 3 3 3 2 WD40-like domain Nup160 PF11715.8 CAM43603.1 - 0.4 9.3 7.8 17 3.9 0.1 4.0 3 2 2 5 5 5 0 Nucleoporin Nup120/160 EF-hand_7 PF13499.6 CAM43604.1 - 5.9e-12 45.9 2.4 3.8e-06 27.2 0.7 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CAM43604.1 - 1.6e-10 39.7 1.7 4.5e-08 32.1 0.1 4.0 3 1 1 4 4 4 1 EF hand EF-hand_6 PF13405.6 CAM43604.1 - 3.9e-09 35.7 0.0 3.1e-06 26.7 0.0 3.5 3 1 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 CAM43604.1 - 9.1e-09 35.0 2.8 8.2e-06 25.6 0.3 3.1 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CAM43604.1 - 3.6e-05 23.1 0.3 0.00013 21.3 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 CAM43604.1 - 0.0021 18.3 0.1 0.86 10.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_14 PF17959.1 CAM43604.1 - 0.0052 17.1 0.0 2.4 8.6 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain UPF0154 PF03672.13 CAM43604.1 - 0.021 14.8 0.0 0.33 11.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 CAM43604.1 - 0.03 15.2 0.0 0.041 14.8 0.0 1.2 1 0 0 1 1 1 0 EF-hand domain Radical_SAM PF04055.21 CAM43604.1 - 0.033 14.6 0.2 0.052 13.9 0.2 1.3 1 0 0 1 1 1 0 Radical SAM superfamily DUF1398 PF07166.11 CAM43604.1 - 0.045 13.8 0.1 0.12 12.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1398) Baculo_p48 PF04878.13 CAM43604.1 - 0.072 12.0 0.0 0.091 11.7 0.0 1.1 1 0 0 1 1 1 0 Baculovirus P48 protein SHIPPO-rpt PF07004.12 CAM43608.1 - 4.4e-19 68.4 42.2 0.075 14.0 0.0 10.0 10 0 0 10 10 10 8 Sperm-tail PG-rich repeat UNC-50 PF05216.13 CAM43609.1 - 2.9e-47 161.1 10.9 3.5e-47 160.8 10.9 1.0 1 0 0 1 1 1 1 UNC-50 family INCENP_N PF12178.8 CAM43610.1 - 0.00052 20.0 0.2 0.0011 19.0 0.2 1.5 1 0 0 1 1 1 1 Chromosome passenger complex (CPC) protein INCENP N terminal PROCN PF08083.11 CAM43611.1 - 5.1e-190 631.5 3.8 1.1e-189 630.4 3.8 1.5 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 CAM43611.1 - 1.9e-91 305.8 0.0 3.1e-91 305.1 0.0 1.3 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 CAM43611.1 - 8.2e-69 230.6 0.1 1.7e-68 229.5 0.1 1.6 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 U5_2-snRNA_bdg PF10597.9 CAM43611.1 - 2.6e-59 199.1 0.1 7.3e-59 197.7 0.1 1.8 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PRO8NT PF08082.11 CAM43611.1 - 1.1e-57 194.3 0.0 3.1e-57 192.8 0.0 1.9 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain RRM_4 PF10598.9 CAM43611.1 - 8.8e-37 125.3 0.1 2.6e-36 123.8 0.1 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 CAM43611.1 - 3.2e-30 104.6 0.0 1.2e-29 102.7 0.0 2.0 2 0 0 2 2 2 1 PROCT (NUC072) domain DUF5480 PF17576.2 CAM43611.1 - 0.016 15.2 0.2 0.037 14.0 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5480) Gly-zipper_Omp PF13488.6 CAM43613.1 - 0.34 10.9 6.3 1 9.4 6.3 1.8 1 0 0 1 1 1 0 Glycine zipper Mito_carr PF00153.27 CAM43614.1 - 2.7e-40 136.2 0.5 3.7e-19 68.4 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein HECT PF00632.25 CAM43615.1 - 1.8e-47 162.3 0.0 3.2e-47 161.5 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Pkinase PF00069.25 CAM43615.1 - 3.5e-46 157.7 0.0 6.8e-46 156.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM43615.1 - 8.1e-31 107.2 0.0 1.7e-30 106.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_1 PF00515.28 CAM43615.1 - 4.7e-13 48.3 1.5 5.8e-06 25.9 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CAM43615.1 - 6.9e-13 47.7 3.6 3.4e-05 23.6 0.1 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 CAM43615.1 - 1.9e-10 40.1 1.2 0.0049 17.0 0.0 4.2 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CAM43615.1 - 7.7e-10 38.3 0.7 3.8e-06 26.5 0.2 3.0 2 1 0 2 2 2 2 TPR repeat TPR_14 PF13428.6 CAM43615.1 - 2.5e-06 27.8 0.3 0.26 12.2 0.2 3.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 CAM43615.1 - 0.0001 22.7 1.2 0.31 11.6 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat Kinase-like PF14531.6 CAM43615.1 - 0.00016 21.1 0.0 0.0005 19.5 0.0 1.8 1 0 0 1 1 1 1 Kinase-like TPR_16 PF13432.6 CAM43615.1 - 0.00022 21.8 0.2 0.00022 21.8 0.2 3.1 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CAM43615.1 - 0.00055 19.8 0.7 0.015 15.3 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat APH PF01636.23 CAM43615.1 - 0.0043 17.0 0.0 0.0043 17.0 0.0 3.0 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 CAM43615.1 - 0.0046 16.3 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CAM43615.1 - 0.0082 15.8 0.0 0.03 13.9 0.0 1.9 1 0 0 1 1 1 1 RIO1 family TPR_17 PF13431.6 CAM43615.1 - 0.015 15.6 0.1 2.1 8.9 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 CAM43615.1 - 0.039 14.2 3.1 0.43 10.9 0.1 3.2 2 1 1 3 3 2 0 Tetratricopeptide repeat tRNA-synt_2c PF01411.19 CAM43615.1 - 0.043 12.3 2.6 0.082 11.4 2.6 1.3 1 0 0 1 1 1 0 tRNA synthetases class II (A) TPR_6 PF13174.6 CAM43615.1 - 0.048 14.3 0.2 3.3 8.6 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 CAM43615.1 - 0.97 9.6 8.2 2.8 8.2 0.2 3.7 3 1 1 4 4 3 0 Tetratricopeptide repeat MIT PF04212.18 CAM43615.1 - 4.2 7.5 6.6 0.92 9.6 0.3 3.2 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain EMP24_GP25L PF01105.24 CAM43615.1 - 5.4 6.9 8.2 0.21 11.5 1.0 2.3 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Pkinase PF00069.25 CAM43616.1 - 4.7e-69 232.7 0.0 5.6e-69 232.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM43616.1 - 1.2e-33 116.5 0.0 1.5e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM43616.1 - 1.9e-05 24.1 0.0 2.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 CAM43616.1 - 0.004 17.8 0.2 0.01 16.6 0.2 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 CAM43616.1 - 0.014 14.3 0.1 0.02 13.9 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain POR PF01558.18 CAM43616.1 - 0.08 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Hydrolase_4 PF12146.8 CAM43617.1 - 6.9e-15 55.0 0.2 1.1e-09 38.0 0.2 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CAM43617.1 - 1.2e-08 35.0 0.1 3.3e-06 26.9 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CAM43617.1 - 1.1e-07 32.6 0.5 1.8e-07 32.0 0.1 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 CAM43617.1 - 5.9e-06 26.2 0.0 0.089 12.6 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 CAM43617.1 - 1.8e-05 24.4 0.0 0.00022 20.8 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 CAM43617.1 - 6e-05 23.0 0.7 0.00013 21.9 0.7 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.11 CAM43617.1 - 0.0002 21.4 0.0 0.00033 20.7 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 CAM43617.1 - 0.00023 20.8 0.0 0.017 14.7 0.0 2.1 1 1 1 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.12 CAM43617.1 - 0.00035 19.3 0.1 0.0038 15.9 0.0 2.1 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 CAM43617.1 - 0.00057 19.6 0.0 0.24 11.0 0.0 2.1 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) DUF1100 PF06500.11 CAM43617.1 - 0.023 13.5 0.0 0.03 13.1 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) FSH1 PF03959.13 CAM43617.1 - 0.065 12.9 0.0 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) PGAP1 PF07819.13 CAM43617.1 - 0.15 11.7 0.2 0.48 10.1 0.2 1.8 1 1 0 1 1 1 0 PGAP1-like protein DEAD PF00270.29 CAM43618.1 - 3.3e-38 131.2 0.0 1.1e-37 129.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAM43618.1 - 2.9e-24 85.6 0.0 1.1e-23 83.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CAM43618.1 - 6.8e-14 51.8 0.0 2.5e-13 50.0 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CAM43618.1 - 0.0014 18.7 0.0 0.0039 17.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DnaJ PF00226.31 CAM43619.1 - 6.1e-15 55.1 0.0 4.6e-09 36.3 0.0 2.6 2 0 0 2 2 2 2 DnaJ domain HXXSHH PF07586.11 CAM43619.1 - 0.00078 19.1 1.8 0.0011 18.6 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1552) TFIIA PF03153.13 CAM43619.1 - 0.0076 16.3 15.4 0.0096 16.0 15.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Activator_LAG-3 PF11498.8 CAM43619.1 - 0.019 13.9 16.5 0.032 13.2 16.5 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DYW_deaminase PF14432.6 CAM43619.1 - 0.051 13.4 1.1 0.086 12.7 1.1 1.4 1 0 0 1 1 1 0 DYW family of nucleic acid deaminases HDOD PF08668.12 CAM43619.1 - 0.1 12.1 0.2 0.15 11.5 0.2 1.2 1 0 0 1 1 1 0 HDOD domain ARA70 PF12489.8 CAM43619.1 - 0.13 12.4 4.9 0.25 11.5 4.9 1.4 1 0 0 1 1 1 0 Nuclear coactivator Spem1 PF15670.5 CAM43619.1 - 0.9 9.1 13.4 0.87 9.1 0.5 2.2 2 0 0 2 2 2 0 Spermatid maturation protein 1 Spt20 PF12090.8 CAM43619.1 - 3.8 7.0 12.5 6.3 6.3 12.5 1.3 1 0 0 1 1 1 0 Spt20 family Pkinase PF00069.25 CAM43621.1 - 9.8e-39 133.3 0.0 8.4e-38 130.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM43621.1 - 4e-21 75.5 0.0 7.2e-20 71.4 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM43621.1 - 1.2e-08 34.7 0.0 2.4e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CAM43621.1 - 0.022 14.7 0.1 0.054 13.4 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-RING_4 PF14570.6 CAM43621.1 - 3.1 7.7 17.9 6.1 6.7 17.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RIIa PF02197.17 CAM43622.1 - 4.1e-10 39.2 0.1 1.2e-09 37.6 0.1 1.9 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit EF-hand_6 PF13405.6 CAM43622.1 - 2.2e-05 24.0 0.2 0.041 13.8 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CAM43622.1 - 0.0085 16.5 0.0 3 8.4 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CAM43622.1 - 0.099 12.2 0.1 3.6 7.3 0.0 3.1 3 0 0 3 3 3 0 EF hand TPR_2 PF07719.17 CAM43623.1 - 6.1e-15 54.1 9.9 0.022 14.9 0.0 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 CAM43623.1 - 1.5e-10 41.4 13.2 5e-05 23.7 0.7 5.0 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 CAM43623.1 - 1e-09 38.3 15.0 0.00037 21.1 0.1 6.7 4 3 3 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 CAM43623.1 - 6.9e-09 35.9 18.6 0.0019 18.4 0.0 5.4 4 2 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 CAM43623.1 - 1.6e-06 27.7 10.1 0.91 9.5 1.7 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 CAM43623.1 - 9.3e-06 25.5 6.4 4.5 7.7 1.4 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 CAM43623.1 - 2.1e-05 24.6 4.1 0.99 9.9 0.0 4.8 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 CAM43623.1 - 4e-05 23.3 13.8 0.03 14.4 0.0 5.2 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 CAM43623.1 - 5.9e-05 23.3 6.7 0.038 14.6 0.7 4.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CAM43623.1 - 6.8e-05 23.4 14.0 0.2 12.4 3.1 4.6 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_15 PF13429.6 CAM43623.1 - 8.6e-05 21.9 4.6 0.019 14.2 0.3 3.3 1 1 0 2 2 2 2 Tetratricopeptide repeat DUF218 PF02698.17 CAM43623.1 - 0.002 18.2 0.6 0.0063 16.5 0.2 2.0 2 1 0 2 2 2 1 DUF218 domain TPR_11 PF13414.6 CAM43623.1 - 0.0036 17.0 8.8 9 6.1 0.2 5.6 5 1 1 6 6 6 1 TPR repeat TPR_6 PF13174.6 CAM43623.1 - 0.0085 16.7 7.2 5 8.0 0.0 5.1 6 0 0 6 6 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CAM43623.1 - 0.027 14.7 10.2 2.1 8.6 2.1 3.8 2 1 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 CAM43623.1 - 0.42 10.7 8.8 0.47 10.5 0.6 3.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_21 PF09976.9 CAM43623.1 - 2.4 7.8 6.8 12 5.5 0.4 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat-like domain SF3b10 PF07189.11 CAM43625.1 - 3.5e-16 59.1 0.0 3.7e-16 59.0 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) SseB PF07179.12 CAM43626.1 - 0.16 12.2 0.0 28 5.0 0.0 2.5 2 0 0 2 2 2 0 SseB protein N-terminal domain HD_3 PF13023.6 CAM43627.1 - 4.5e-40 137.3 0.0 5.4e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 CAM43627.1 - 7.5e-12 45.4 0.0 1.1e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 CAM43627.1 - 8.5e-07 29.2 0.0 1.3e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 HD domain RRM_1 PF00076.22 CAM43630.1 - 4.2e-72 237.9 0.0 6.2e-17 61.2 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CAM43630.1 - 2.4e-24 85.3 0.1 4.6e-24 84.4 0.1 1.5 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_occluded PF16842.5 CAM43630.1 - 4.3e-09 36.1 0.0 0.1 12.5 0.0 3.8 4 0 0 4 4 4 3 Occluded RNA-recognition motif RRM_3 PF08777.11 CAM43630.1 - 4.9e-08 33.0 4.6 0.19 11.8 0.6 4.3 3 1 1 4 4 4 3 RNA binding motif Nup35_RRM_2 PF14605.6 CAM43630.1 - 2.2e-07 30.8 0.0 0.056 13.4 0.0 4.0 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CAM43630.1 - 2.3e-05 24.4 0.1 0.26 11.4 0.0 5.0 5 3 0 5 5 5 1 RNA recognition motif RRM_5 PF13893.6 CAM43630.1 - 0.00053 19.6 0.0 0.016 14.8 0.0 2.8 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CAM43630.1 - 0.043 13.9 0.7 1.6 8.9 0.0 3.3 3 1 0 3 3 3 0 Limkain b1 RRM_8 PF11835.8 CAM43630.1 - 0.048 13.9 0.0 18 5.7 0.0 2.7 2 0 0 2 2 2 0 RRM-like domain TB2_DP1_HVA22 PF03134.19 CAM43631.1 - 0.064 13.2 0.9 0.064 13.2 0.9 1.7 2 0 0 2 2 2 0 TB2/DP1, HVA22 family GTP_EFTU PF00009.27 CAM43632.1 - 9.2e-43 146.0 0.0 2.5e-40 138.1 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CAM43632.1 - 1.7e-13 50.9 0.0 3.5e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 CAM43632.1 - 0.0017 18.4 0.1 0.0074 16.4 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF2009 PF09418.10 CAM43633.1 - 2e-174 580.9 0.0 2.3e-174 580.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) RNA_pol_Rpc4 PF05132.14 CAM43634.1 - 1.3e-07 32.1 0.0 3.8e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase III RPC4 BBS1 PF14779.6 CAM43635.1 - 3.4e-79 265.9 0.0 6.2e-79 265.0 0.0 1.4 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 1 PHTB1_N PF14727.6 CAM43635.1 - 0.00086 18.8 0.0 0.0055 16.1 0.0 2.2 3 0 0 3 3 3 1 PTHB1 N-terminus BBS2_Mid PF14783.6 CAM43635.1 - 0.015 15.3 0.0 4.7 7.3 0.0 3.2 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region VMA21 PF09446.10 CAM43636.1 - 1.3e-05 25.2 9.6 1.9e-05 24.7 9.6 1.2 1 0 0 1 1 1 1 VMA21-like domain DUF2207 PF09972.9 CAM43636.1 - 0.038 12.8 0.0 0.042 12.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TssN PF17555.2 CAM43636.1 - 0.11 11.9 3.0 0.12 11.7 2.3 1.4 1 1 0 1 1 1 0 Type VI secretion system, TssN BPD_transp_1 PF00528.22 CAM43636.1 - 0.18 11.5 3.4 0.26 11.0 3.4 1.2 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component SOG2 PF10428.9 CAM43636.1 - 0.81 8.8 6.1 0.94 8.6 6.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Syja_N PF02383.18 CAM43638.1 - 5.6e-22 78.5 0.0 3e-21 76.1 0.0 2.0 1 1 0 1 1 1 1 SacI homology domain Raf1_HTH PF18579.1 CAM43639.1 - 0.16 11.6 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain Methyltransf_23 PF13489.6 CAM43640.1 - 4.2e-19 69.0 0.0 5.6e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAM43640.1 - 4.6e-18 65.7 0.0 7.4e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAM43640.1 - 6.3e-16 58.5 0.0 1.3e-15 57.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAM43640.1 - 4.5e-15 56.1 0.0 9.9e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAM43640.1 - 2.2e-12 47.6 0.0 6.3e-12 46.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CAM43640.1 - 4.1e-08 32.8 0.0 1.3e-07 31.2 0.0 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 CAM43640.1 - 6.9e-07 29.4 0.0 1e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CAM43640.1 - 2.9e-06 26.9 0.1 4.2e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 CAM43640.1 - 5.7e-06 26.1 0.3 2.8e-05 23.8 0.3 1.8 1 1 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 CAM43640.1 - 7.2e-05 22.4 0.1 0.00016 21.3 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Pox_MCEL PF03291.16 CAM43640.1 - 0.00091 18.4 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme Ubie_methyltran PF01209.18 CAM43640.1 - 0.0011 18.4 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 CAM43640.1 - 0.0044 16.8 0.1 0.0067 16.2 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 CAM43640.1 - 0.0096 15.5 0.9 0.2 11.2 0.1 2.4 3 0 0 3 3 3 1 Methionine biosynthesis protein MetW TPMT PF05724.11 CAM43640.1 - 0.025 14.2 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) TehB PF03848.14 CAM43640.1 - 0.047 13.1 0.0 0.11 11.9 0.0 1.7 1 1 0 1 1 1 0 Tellurite resistance protein TehB SAS-6_N PF16531.5 CAM43643.2 - 8.2e-19 68.0 0.0 1.9e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal DUF16 PF01519.16 CAM43643.2 - 0.0038 17.7 4.1 0.0038 17.7 4.1 4.0 2 2 1 3 3 3 1 Protein of unknown function DUF16 DUF2935 PF11155.8 CAM43643.2 - 0.38 11.1 7.9 0.2 12.0 0.8 3.5 2 2 0 3 3 3 0 Domain of unknown function (DUF2935) GAS PF13851.6 CAM43643.2 - 2.5 7.4 44.4 0.15 11.4 6.8 3.5 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding bZIP_2 PF07716.15 CAM43643.2 - 3.8 7.7 16.0 3.4 7.8 0.7 3.7 3 0 0 3 3 3 0 Basic region leucine zipper Tweety PF04906.13 CAM43643.2 - 6.4 5.3 8.7 0.51 9.0 1.3 2.3 1 1 1 2 2 2 0 Tweety bZIP_1 PF00170.21 CAM43643.2 - 9.4 6.4 24.9 0.53 10.4 8.0 3.9 4 0 0 4 4 4 0 bZIP transcription factor MGC-24 PF05283.11 CAM43644.1 - 3.1 8.3 9.7 0.24 11.8 3.3 2.2 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF2353 PF09789.9 CAM43645.1 - 0.021 14.2 2.8 0.035 13.5 2.8 1.3 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Cyclin_C PF02984.19 CAM43646.1 - 0.62 10.2 4.2 2.3 8.3 0.8 2.1 1 1 1 2 2 2 0 Cyclin, C-terminal domain Hydrolase_6 PF13344.6 CAM43647.1 - 9.4e-25 86.7 0.0 2e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CAM43647.1 - 1.3e-13 50.8 0.0 3.2e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 CAM43647.1 - 0.0019 18.5 0.0 0.0082 16.5 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PIH1 PF08190.12 CAM43648.1 - 1.4e-60 203.5 0.1 2.5e-60 202.7 0.1 1.4 1 0 0 1 1 1 1 PIH1 N-terminal domain PIH1_CS PF18201.1 CAM43648.1 - 8.3e-24 83.9 0.0 1.8e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 PIH1 CS-like domain Mo25 PF08569.11 CAM43649.1 - 0.014 14.8 0.1 0.023 14.1 0.1 1.3 1 0 0 1 1 1 0 Mo25-like PGAP1 PF07819.13 CAM43650.1 - 3e-12 46.8 0.0 6.9e-05 22.7 0.0 3.1 3 2 0 3 3 3 2 PGAP1-like protein Abhydrolase_1 PF00561.20 CAM43650.1 - 0.0082 15.8 0.0 0.031 13.9 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CAM43650.1 - 0.028 13.7 0.0 0.065 12.5 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DNA_pol_B_exo1 PF03104.19 CAM43651.2 - 3.3e-57 194.1 0.1 7.6e-57 192.9 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DUF1744 PF08490.12 CAM43651.2 - 1.5e-51 175.2 0.0 1.6e-50 171.9 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo2 PF10108.9 CAM43651.2 - 1.7e-10 40.9 0.1 3.3e-08 33.5 0.1 2.5 2 0 0 2 2 2 2 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B PF00136.21 CAM43651.2 - 3.1e-10 39.3 0.5 5.6e-08 31.9 0.3 3.5 3 1 0 3 3 3 1 DNA polymerase family B RNase_H_2 PF13482.6 CAM43651.2 - 1.5e-07 31.6 0.2 4.6e-07 30.0 0.1 2.0 2 0 0 2 2 2 1 RNase_H superfamily G2BR PF18442.1 CAM43651.2 - 0.06 13.0 1.7 0.34 10.6 1.7 2.3 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) YopE_N PF09020.10 CAM43651.2 - 0.16 12.2 0.0 0.41 10.9 0.0 1.6 1 0 0 1 1 1 0 YopE, N terminal zf-3CxxC PF13695.6 CAM43652.1 - 7.8e-06 26.3 4.0 8.8e-06 26.1 4.0 1.2 1 0 0 1 1 1 1 Zinc-binding domain zf-3CxxC_2 PF17180.4 CAM43652.1 - 0.0077 17.0 8.1 0.014 16.1 8.1 1.5 1 1 0 1 1 1 1 Zinc-binding domain HC2 PF07382.11 CAM43653.1 - 1.2e-08 35.3 38.3 0.00017 21.7 25.1 3.2 1 1 3 4 4 4 4 Histone H1-like nucleoprotein HC2 DTHCT PF08070.11 CAM43653.1 - 9.5e-08 32.7 85.7 0.21 12.4 15.2 5.4 1 1 4 5 5 5 5 DTHCT (NUC029) region TPR_12 PF13424.6 CAM43654.2 - 0.00014 22.1 13.1 0.36 11.1 1.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat Snf7 PF03357.21 CAM43655.1 - 7.2e-13 48.5 20.3 7.2e-13 48.5 20.3 1.7 1 1 1 2 2 2 1 Snf7 Mating_C PF12737.7 CAM43655.1 - 0.57 9.3 3.6 0.11 11.8 0.3 1.6 2 1 0 2 2 2 0 C-terminal domain of homeodomain 1 PIN_8 PF18476.1 CAM43655.1 - 8.5 6.2 11.7 0.95 9.3 5.8 1.9 1 1 1 2 2 2 0 PIN like domain AA_permease_2 PF13520.6 CAM43656.1 - 5.7e-38 130.9 48.5 7.5e-38 130.5 48.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CAM43656.1 - 1.7e-05 23.6 44.0 3.2e-05 22.7 44.0 1.5 1 1 0 1 1 1 1 Amino acid permease Mito_carr PF00153.27 CAM43657.1 - 7.9e-30 102.6 7.6 3.9e-16 58.8 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein ArsB PF02040.15 CAM43657.1 - 0.043 13.1 0.2 0.063 12.6 0.2 1.2 1 0 0 1 1 1 0 Arsenical pump membrane protein Mito_carr PF00153.27 CAM43658.1 - 3e-30 104.0 7.5 1.5e-16 60.1 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein ArsB PF02040.15 CAM43658.1 - 0.054 12.8 0.3 0.08 12.3 0.3 1.2 1 0 0 1 1 1 0 Arsenical pump membrane protein zf-CCCH_3 PF15663.5 CAM43660.1 - 0.027 14.7 0.0 0.069 13.4 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 CAM43660.1 - 0.068 13.7 6.1 0.14 12.6 6.1 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 CAM43660.1 - 0.069 13.0 7.0 0.35 10.7 7.0 2.1 1 1 0 1 1 1 0 CCCH-type zinc finger zf-CCCH PF00642.24 CAM43660.1 - 0.3 11.0 2.6 0.62 10.0 2.6 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CAM43660.1 - 1.5 9.0 8.0 1.3 9.2 1.6 2.4 2 0 0 2 2 2 0 Zinc finger domain LSM PF01423.22 CAM43661.1 - 1.3e-19 69.6 0.0 1.5e-19 69.4 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CAM43661.1 - 0.00037 20.6 0.0 0.00039 20.5 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 CAM43661.1 - 0.12 12.5 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain CS PF04969.16 CAM43662.1 - 4.3e-10 40.5 0.0 6.1e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 CS domain ARL2_Bind_BART PF11527.8 CAM43663.1 - 3.2e-09 36.9 0.4 4.3e-09 36.5 0.4 1.2 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART zf-ANAPC11 PF12861.7 CAM43665.1 - 6.2e-29 99.9 10.2 6.8e-29 99.8 10.2 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CAM43665.1 - 2.4e-18 66.1 12.4 3.3e-18 65.7 12.4 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CAM43665.1 - 1.1e-06 28.3 17.7 1.3e-05 24.9 7.9 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CAM43665.1 - 3.3e-06 27.3 21.0 8e-05 22.9 19.6 2.6 1 1 1 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 CAM43665.1 - 2.5e-05 24.2 12.3 5.5e-05 23.1 12.3 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CAM43665.1 - 0.00027 20.7 17.1 0.00032 20.5 15.6 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CAM43665.1 - 0.00049 20.0 18.9 0.0043 17.0 17.6 2.5 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CAM43665.1 - 0.0017 18.2 17.5 0.086 12.7 10.9 2.7 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CAM43665.1 - 0.0031 17.3 3.1 0.0031 17.3 3.1 2.8 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 CAM43665.1 - 0.0054 16.3 5.1 0.0054 16.3 5.1 1.8 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 CAM43665.1 - 0.0066 16.2 15.0 0.23 11.3 15.0 2.5 1 1 0 1 1 1 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 CAM43665.1 - 0.021 15.0 4.4 0.021 15.0 4.4 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-HIT PF04438.16 CAM43665.1 - 0.32 10.9 10.9 0.65 9.9 5.9 2.4 2 1 0 2 2 2 0 HIT zinc finger zf-Nse PF11789.8 CAM43665.1 - 0.87 9.5 10.3 1.4 8.8 10.3 1.4 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.29 CAM43665.1 - 4.2 7.4 15.0 65 3.5 15.0 2.5 1 1 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 CAM43665.1 - 9 6.7 17.3 85 3.6 17.3 2.4 1 1 0 1 1 1 0 RING-like domain DUF2833 PF11090.8 CAM43666.1 - 0.034 14.5 0.0 0.057 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2833) DUF962 PF06127.11 CAM43667.1 - 2e-21 75.9 3.6 4.7e-21 74.7 3.6 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Malate_synthase PF01274.22 CAM43668.1 - 0.16 10.2 0.0 0.22 9.7 0.0 1.1 1 0 0 1 1 1 0 Malate synthase FPL PF09758.9 CAM43669.1 - 6e-52 175.6 1.9 1.2e-51 174.7 1.9 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein DNA_pol3_tau_5 PF12170.8 CAM43669.1 - 0.043 13.9 1.3 2.1 8.4 0.2 2.4 2 0 0 2 2 2 0 DNA polymerase III tau subunit V interacting with alpha SET PF00856.28 CAM43670.1 - 2.7e-37 128.7 0.1 7.8e-06 26.4 0.0 8.4 7 2 0 7 7 7 5 SET domain 60KD_IMP PF02096.20 CAM43673.1 - 0.00015 21.8 0.0 0.00022 21.2 0.0 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein PS_Dcarbxylase PF02666.15 CAM43674.1 - 5.8e-38 130.5 0.0 7.5e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase DUF3361 PF11841.8 CAM43675.1 - 0.077 12.9 0.5 21 5.0 0.2 2.8 2 1 0 3 3 3 0 Domain of unknown function (DUF3361) GIT_CC PF16559.5 CAM43675.1 - 1.1 9.2 6.3 17 5.4 4.3 3.3 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor RBD-FIP PF09457.10 CAM43675.1 - 3.2 7.7 6.3 3.9 7.5 0.1 3.6 3 0 0 3 3 3 0 FIP domain DUF4055 PF13264.6 CAM43675.1 - 5.8 7.1 8.6 8 6.6 0.1 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4055) Pkinase PF00069.25 CAM43677.1 - 9.4e-12 44.8 0.0 3.8e-11 42.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM43677.1 - 0.0002 20.8 0.0 0.00035 19.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase DnaJ PF00226.31 CAM43678.1 - 1.1e-13 51.1 0.2 2.2e-13 50.1 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain Cgr1 PF03879.14 CAM43679.1 - 5.5e-06 26.7 22.3 6.5e-06 26.5 22.3 1.1 1 0 0 1 1 1 1 Cgr1 family Med8 PF10232.9 CAM43679.1 - 0.0066 16.1 5.2 0.0077 15.9 5.2 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 EcoRII-C PF09019.11 CAM43679.1 - 0.0073 16.4 2.3 0.0091 16.1 2.2 1.4 1 1 0 1 1 1 1 EcoRII C terminal LPP20 PF02169.16 CAM43679.1 - 0.023 15.0 1.9 0.028 14.8 1.9 1.2 1 0 0 1 1 1 0 LPP20 lipoprotein FAM178 PF14816.6 CAM43679.1 - 0.17 10.8 4.7 0.19 10.7 4.7 1.1 1 0 0 1 1 1 0 Family of unknown function, FAM178 AAA_11 PF13086.6 CAM43679.1 - 0.24 11.1 11.4 0.26 11.0 11.4 1.0 1 0 0 1 1 1 0 AAA domain NAM-associated PF14303.6 CAM43679.1 - 3.1 8.5 17.7 3.8 8.2 17.7 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Atg14 PF10186.9 CAM43679.1 - 6.1 5.8 16.1 6.5 5.7 16.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SieB PF14163.6 CAM43679.1 - 9.3 5.7 7.6 1.1 8.8 1.3 2.0 1 1 1 2 2 2 0 Super-infection exclusion protein B DSPc PF00782.20 CAM43680.1 - 1.3e-20 73.6 0.0 1.9e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CAM43680.1 - 0.012 15.3 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase zf-SNAP50_C PF12251.8 CAM43681.1 - 5e-37 127.5 0.1 7.4e-37 127.0 0.1 1.2 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal Katanin_con80 PF13925.6 CAM43682.1 - 1.1e-27 97.1 0.0 1.4e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 con80 domain of Katanin WD40 PF00400.32 CAM43682.1 - 1.2e-26 92.4 8.2 3.1e-06 27.8 0.4 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM43682.1 - 3.5e-14 52.9 0.0 1.1e-06 28.8 0.0 3.7 1 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CAM43682.1 - 0.00051 19.5 0.0 0.013 14.8 0.0 2.4 1 1 1 2 2 2 1 WD40-like domain eIF2A PF08662.11 CAM43682.1 - 0.0028 17.6 0.0 2.3 8.1 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CAM43682.1 - 0.065 12.2 0.0 0.71 8.8 0.0 2.3 1 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 CAM43682.1 - 0.074 11.3 0.0 1.8 6.8 0.0 2.2 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 CAM43682.1 - 0.2 10.3 0.4 0.9 8.1 0.1 2.3 1 1 3 4 4 4 0 Nucleoporin Nup120/160 ParcG PF10274.9 CAM43683.1 - 4.9e-74 248.4 0.0 6.1e-74 248.1 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein Kinesin PF00225.23 CAM43684.1 - 3.9e-56 190.4 0.9 1e-55 189.0 0.9 1.6 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CAM43684.1 - 1.5e-08 34.7 0.0 3e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 CAM43684.1 - 0.0078 16.6 0.1 0.02 15.3 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain DUF87 PF01935.17 CAM43684.1 - 0.052 13.6 0.1 0.31 11.1 0.0 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_22 PF13401.6 CAM43684.1 - 0.12 12.7 0.5 0.3 11.3 0.5 1.9 1 1 0 1 1 1 0 AAA domain HSP70 PF00012.20 CAM43685.1 - 8.4e-63 212.5 0.0 1.5e-62 211.7 0.0 1.4 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CAM43685.1 - 0.0038 16.1 0.0 0.02 13.7 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein GCV_H PF01597.19 CAM43686.1 - 3.8e-40 136.6 1.0 4.3e-40 136.4 1.0 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 CAM43686.1 - 1.1e-06 28.4 0.3 2e-06 27.5 0.3 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme PTS_EIIA_1 PF00358.20 CAM43686.1 - 6.5e-05 22.7 0.1 9.5e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 RnfC_N PF13375.6 CAM43686.1 - 0.00016 21.6 0.3 0.00024 21.0 0.3 1.2 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain MS_channel PF00924.18 CAM43686.1 - 0.098 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel Gp_dh_N PF00044.24 CAM43688.1 - 2.8e-15 56.5 0.0 5.7e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 CAM43688.1 - 3.2e-14 52.8 0.1 5.2e-14 52.1 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Pro_isomerase PF00160.21 CAM43690.1 - 2.2e-46 158.0 0.4 3.7e-46 157.3 0.4 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 CAM43690.1 - 1.3e-07 31.1 0.2 0.021 14.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CAM43690.1 - 1.5e-06 27.7 0.1 0.036 13.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 CAM43690.1 - 0.00019 21.5 0.6 0.00041 20.4 0.6 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 CAM43690.1 - 0.00064 20.2 0.4 0.67 10.7 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CAM43690.1 - 0.0021 18.1 0.6 0.34 11.2 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CAM43690.1 - 0.0064 17.0 2.5 2.8 8.5 0.1 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 CAM43690.1 - 0.013 16.2 1.0 0.049 14.3 1.0 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 CAM43690.1 - 0.043 14.1 1.4 0.78 10.1 0.7 2.6 1 1 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CAM43690.1 - 0.098 12.9 2.2 0.4 10.9 0.4 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 CAM43690.1 - 0.13 13.2 2.7 0.56 11.2 0.4 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CAM43690.1 - 1.2 9.2 3.3 4.3 7.5 0.1 2.8 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat HemY_N PF07219.13 CAM43690.1 - 1.7 8.9 6.9 5.9 7.1 1.6 3.0 2 1 1 3 3 3 0 HemY protein N-terminus SCAMP PF04144.13 CAM43692.1 - 1.2e-37 129.9 16.0 1.4e-37 129.7 16.0 1.0 1 0 0 1 1 1 1 SCAMP family DUF1129 PF06570.11 CAM43692.1 - 0.08 12.4 10.0 0.18 11.3 10.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) CPP1-like PF11833.8 CAM43692.1 - 0.094 12.4 2.0 0.52 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like A_deaminase PF00962.22 CAM43693.2 - 1.1e-116 389.8 0.0 8.3e-87 291.6 0.0 2.4 2 0 0 2 2 2 2 Adenosine/AMP deaminase BRCT_2 PF16589.5 CAM43694.1 - 9.4e-07 29.2 0.0 7.1e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 CAM43694.1 - 0.0011 19.4 0.0 0.016 15.5 0.0 2.6 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 CAM43694.1 - 0.06 13.7 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain His_Phos_1 PF00300.22 CAM43695.1 - 1.3e-10 41.4 0.0 0.0003 20.5 0.0 3.3 3 1 0 3 3 3 3 Histidine phosphatase superfamily (branch 1) Nitrate_red_del PF02613.15 CAM43697.1 - 0.045 13.8 0.0 0.15 12.1 0.0 2.0 1 1 0 1 1 1 0 Nitrate reductase delta subunit Proteasome PF00227.26 CAM43698.1 - 8.8e-38 129.7 0.0 1.3e-37 129.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CAM43698.1 - 1.5e-11 43.8 0.2 1.5e-11 43.8 0.2 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature FAM184 PF15665.5 CAM43700.1 - 0.0027 17.5 15.9 0.0027 17.5 15.9 8.7 1 1 7 9 9 9 5 Family with sequence similarity 184, A and B TPR_1 PF00515.28 CAM43701.1 - 2.4e-12 46.1 9.6 2.4e-05 24.0 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CAM43701.1 - 1.5e-08 34.1 6.8 1e-07 31.5 0.8 2.5 1 1 1 2 2 2 1 TPR repeat TPR_2 PF07719.17 CAM43701.1 - 3e-08 33.1 19.0 0.00054 19.9 0.1 4.0 3 1 1 4 4 3 2 Tetratricopeptide repeat UPF0121 PF03661.13 CAM43701.1 - 5.9e-06 25.9 8.7 0.00012 21.6 8.7 2.1 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0121) TPR_17 PF13431.6 CAM43701.1 - 3.3e-05 23.9 1.3 3.3e-05 23.9 1.3 2.1 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 CAM43701.1 - 5e-05 23.2 6.6 0.011 15.9 1.7 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CAM43701.1 - 0.00017 21.8 5.3 0.0039 17.4 2.6 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CAM43701.1 - 0.00018 22.1 0.5 0.00018 22.1 0.5 2.6 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CAM43701.1 - 0.011 15.7 0.9 0.76 10.0 0.2 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat Tap-RNA_bind PF09162.10 CAM43701.1 - 0.066 13.1 0.1 0.19 11.6 0.1 1.7 1 0 0 1 1 1 0 Tap, RNA-binding ANAPC3 PF12895.7 CAM43701.1 - 0.28 11.4 2.8 0.54 10.5 2.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CAM43701.1 - 0.36 10.8 8.2 1.5 8.8 2.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CAM43701.1 - 0.93 10.5 7.4 8.6 7.5 0.1 3.9 2 1 2 4 4 4 0 Tetratricopeptide repeat Rad51 PF08423.11 CAM43702.1 - 3.9e-122 406.4 0.0 5e-122 406.1 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 CAM43702.1 - 1.4e-12 47.7 0.2 1.8e-12 47.3 0.2 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 CAM43702.1 - 7.8e-08 32.8 1.0 2.2e-07 31.4 0.6 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 CAM43702.1 - 6.6e-07 28.9 0.1 1.3e-06 28.0 0.1 1.5 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 CAM43702.1 - 1.2e-06 28.3 0.0 3.4e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.15 CAM43702.1 - 0.07 12.4 0.1 0.15 11.4 0.1 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_24 PF13479.6 CAM43702.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 CAM43704.1 - 4.3e-58 196.1 0.0 6.8e-58 195.4 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 CAM43704.1 - 2.5e-15 56.7 0.0 7e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 CAM43704.1 - 1e-11 44.8 1.2 2e-11 43.8 1.2 1.4 1 0 0 1 1 1 1 MCM OB domain AAA_5 PF07728.14 CAM43704.1 - 0.00034 20.6 0.0 0.0012 18.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CAM43704.1 - 0.00042 19.8 0.0 0.025 13.9 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CAM43704.1 - 0.013 15.4 0.0 0.038 13.9 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TTL PF03133.15 CAM43705.1 - 1.8e-75 253.8 0.0 2.9e-75 253.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CAM43705.1 - 0.00029 20.2 0.0 0.0027 17.0 0.0 2.3 2 1 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CAM43705.1 - 0.097 11.9 0.0 2.3 7.4 0.0 2.1 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp PepSY_TM_like_2 PF16357.5 CAM43706.1 - 0.21 11.6 0.4 0.33 10.9 0.4 1.3 1 0 0 1 1 1 0 Putative PepSY_TM-like DUF4692 PF15763.5 CAM43706.1 - 0.75 10.3 3.9 3.2 8.2 1.3 2.2 1 1 1 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) SUIM_assoc PF16619.5 CAM43707.1 - 9.1e-07 28.8 0.0 0.48 10.5 0.0 4.4 3 1 0 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 zf-CCCH_4 PF18044.1 CAM43707.1 - 0.0015 18.3 4.1 0.0023 17.7 4.1 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 CAM43707.1 - 0.0021 17.9 4.2 0.0039 17.1 4.2 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 CAM43707.1 - 0.12 12.8 3.1 0.23 12.0 3.1 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 CAM43707.1 - 0.5 10.5 5.5 0.89 9.7 5.5 1.4 1 0 0 1 1 1 0 Zinc finger domain Keratin_2_head PF16208.5 CAM43708.1 - 1.2 9.3 21.9 1.7 8.7 21.9 1.3 1 0 0 1 1 1 0 Keratin type II head PAP2_C PF14360.6 CAM43710.1 - 6e-20 71.5 8.7 6e-20 71.5 8.7 2.1 2 0 0 2 2 2 1 PAP2 superfamily C-terminal PAP2 PF01569.21 CAM43710.1 - 0.26 11.0 11.1 0.091 12.5 7.8 1.9 2 1 0 2 2 2 0 PAP2 superfamily PSP1 PF04468.12 CAM43711.1 - 6.8e-19 67.9 1.2 9.8e-19 67.4 1.2 1.2 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Pkinase PF00069.25 CAM43712.1 - 4.7e-68 229.4 0.0 5.7e-68 229.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM43712.1 - 4.9e-30 104.7 0.0 1.9e-29 102.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM43712.1 - 1.9e-06 27.4 0.1 0.00013 21.4 0.0 2.2 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 CAM43712.1 - 0.011 15.4 0.2 0.062 12.9 0.0 1.9 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CAM43712.1 - 0.018 15.0 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CAM43712.1 - 0.03 13.4 0.0 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 AAA_lid_5 PF17865.1 CAM43713.1 - 0.0019 18.2 0.1 0.0063 16.6 0.1 1.9 1 0 0 1 1 1 1 Midasin AAA lid domain RRM_1 PF00076.22 CAM43715.2 - 1.4e-77 255.5 3.5 1.5e-20 72.8 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CAM43715.2 - 1.5e-21 76.3 0.3 1.2e-20 73.4 0.1 2.2 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 CAM43715.2 - 1.1e-09 37.9 0.1 0.00025 20.6 0.0 3.3 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 CAM43715.2 - 5.4e-06 26.3 0.1 0.072 12.9 0.0 3.5 2 1 1 3 3 3 1 Protein of unknown function (DUF4523) RRM_3 PF08777.11 CAM43715.2 - 0.00012 22.1 0.7 1.9 8.6 0.3 4.2 4 0 0 4 4 4 1 RNA binding motif RRM_7 PF16367.5 CAM43715.2 - 0.00018 21.6 0.6 0.4 10.8 0.1 3.7 4 2 0 4 4 4 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CAM43715.2 - 0.00021 21.2 0.6 1.1 9.4 0.1 4.1 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_8 PF11835.8 CAM43715.2 - 0.0041 17.3 0.1 0.9 9.8 0.0 2.9 4 0 0 4 4 3 1 RRM-like domain SET_assoc PF11767.8 CAM43715.2 - 0.022 14.4 1.4 8.8 6.1 0.0 3.5 4 0 0 4 4 4 0 Histone lysine methyltransferase SET associated Pkinase_C PF00433.24 CAM43715.2 - 0.031 15.0 0.0 0.11 13.3 0.0 2.0 1 0 0 1 1 1 0 Protein kinase C terminal domain XS PF03468.14 CAM43715.2 - 0.18 12.1 2.4 9.3 6.6 0.2 3.2 2 1 1 3 3 3 0 XS domain bVLRF1 PF18826.1 CAM43717.2 - 3.8e-38 130.7 0.0 8.6e-38 129.5 0.0 1.6 1 1 0 1 1 1 1 bacteroidetes VLRF1 release factor acVLRF1 PF18859.1 CAM43717.2 - 0.0034 17.7 0.2 0.012 15.9 0.2 1.9 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor TF_Zn_Ribbon PF08271.12 CAM43718.1 - 0.072 12.6 0.5 0.2 11.2 0.5 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding DUF1664 PF07889.12 CAM43719.1 - 0.00018 21.6 0.2 0.00037 20.5 0.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) DUF4140 PF13600.6 CAM43719.1 - 0.0042 17.5 1.0 2.1 8.8 0.0 2.2 1 1 1 2 2 2 2 N-terminal domain of unknown function (DUF4140) PI3K_P85_iSH2 PF16454.5 CAM43719.1 - 0.0089 15.6 0.6 0.01 15.4 0.6 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DivIC PF04977.15 CAM43719.1 - 0.032 14.0 3.0 2.1 8.2 0.4 2.2 2 0 0 2 2 2 0 Septum formation initiator Mod_r PF07200.13 CAM43719.1 - 0.039 14.1 3.5 0.054 13.6 3.5 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein ABC_tran_CTD PF16326.5 CAM43719.1 - 0.043 14.1 3.3 0.54 10.6 0.3 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain CENP-Q PF13094.6 CAM43719.1 - 0.15 12.3 2.6 0.22 11.7 2.6 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit APG6_N PF17675.1 CAM43719.1 - 0.49 10.9 5.7 1.1 9.8 5.7 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region FliT PF05400.13 CAM43719.1 - 0.93 10.4 5.4 1.2 10.0 3.9 1.9 2 1 0 2 2 2 0 Flagellar protein FliT PRORP PF16953.5 CAM43720.1 - 1.1e-30 106.9 0.4 2.9e-21 76.1 0.7 2.3 2 0 0 2 2 2 2 Protein-only RNase P PPR_long PF17177.4 CAM43720.1 - 0.03 13.7 0.5 0.14 11.5 0.2 2.2 2 1 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP RNase_Zc3h12a PF11977.8 CAM43720.1 - 0.046 13.5 0.0 0.75 9.6 0.0 2.4 2 0 0 2 2 2 0 Zc3h12a-like Ribonuclease NYN domain Ribosomal_L37e PF01907.19 CAM43721.1 - 4.6e-20 71.5 7.9 7.4e-20 70.9 7.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e PseudoU_synth_2 PF00849.22 CAM43722.1 - 1.9e-24 86.5 0.1 3.4e-24 85.8 0.1 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase ALF PF03752.13 CAM43722.1 - 0.003 17.5 1.7 0.012 15.6 1.7 2.1 1 0 0 1 1 1 1 Short repeats of unknown function Methyltransf_23 PF13489.6 CAM43725.1 - 1e-05 25.4 0.0 1.4e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAM43725.1 - 1.9e-05 25.2 0.0 0.00071 20.2 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAM43725.1 - 0.0012 18.7 0.0 0.083 12.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAM43725.1 - 0.0043 17.8 0.0 0.01 16.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAM43725.1 - 0.0047 17.6 0.0 0.28 11.9 0.0 2.6 1 1 1 2 2 2 1 Methyltransferase domain Pex16 PF08610.10 CAM43725.1 - 0.006 15.8 0.0 2.4 7.2 0.0 2.1 2 0 0 2 2 2 2 Peroxisomal membrane protein (Pex16) BT1 PF03092.16 CAM43726.1 - 2.8e-205 682.5 12.8 3.5e-205 682.2 12.8 1.0 1 0 0 1 1 1 1 BT1 family AAA_18 PF13238.6 CAM43728.1 - 4.9e-06 27.1 0.0 9.3e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CAM43728.1 - 8.5e-05 22.9 0.0 0.00015 22.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CAM43728.1 - 0.00011 22.4 0.0 0.00051 20.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CAM43728.1 - 0.00021 20.6 0.0 0.00032 20.0 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin ATPase_2 PF01637.18 CAM43728.1 - 0.0053 16.7 0.0 0.0085 16.0 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 CAM43728.1 - 0.014 15.8 0.0 0.021 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 CAM43728.1 - 0.015 15.4 0.0 0.037 14.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 CAM43728.1 - 0.048 13.6 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_22 PF13401.6 CAM43728.1 - 0.048 13.9 0.0 0.085 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CAM43728.1 - 0.056 13.8 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 CAM43728.1 - 0.073 13.5 0.0 0.2 12.1 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CAM43728.1 - 0.13 12.2 0.0 0.44 10.5 0.0 1.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 CAM43729.1 - 0.00039 20.5 0.0 0.00071 19.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TniB PF05621.11 CAM43729.1 - 0.0096 15.3 0.0 0.023 14.1 0.0 1.6 2 0 0 2 2 2 1 Bacterial TniB protein AAA_16 PF13191.6 CAM43729.1 - 0.042 14.2 0.0 0.078 13.4 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 CAM43729.1 - 0.2 11.2 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B Pkinase PF00069.25 CAM43731.1 - 3.2e-56 190.6 0.0 4.7e-56 190.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM43731.1 - 3.4e-34 118.3 0.0 5.2e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 CAM43731.1 - 2.3e-10 40.9 0.0 4.7e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 CAM43731.1 - 3.8e-07 29.7 0.0 6.5e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.6 CAM43731.1 - 0.0015 18.9 0.2 0.0039 17.6 0.2 1.7 1 1 0 1 1 1 1 Pleckstrin homology domain Mcp5_PH PF12814.7 CAM43731.1 - 0.033 14.3 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology Haspin_kinase PF12330.8 CAM43731.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain zf_CCCH_4 PF18345.1 CAM43732.1 - 0.00061 19.8 5.4 0.042 13.9 0.2 2.8 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 CAM43732.1 - 0.00064 19.9 0.5 0.00064 19.9 0.5 1.8 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH PF00642.24 CAM43732.1 - 0.003 17.4 5.7 0.005 16.7 0.1 2.4 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 CAM43732.1 - 0.074 13.6 9.7 2.3 8.8 0.5 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 CAM43732.1 - 0.42 10.5 5.7 1.6 8.6 0.2 3.1 3 0 0 3 3 3 0 CCCH-type zinc finger Torus PF16131.5 CAM43732.1 - 2.7 8.7 5.3 7.2 7.4 1.0 2.4 1 1 1 2 2 2 0 Torus domain MMR_HSR1 PF01926.23 CAM43733.1 - 9.1e-13 48.3 0.0 1.2e-11 44.6 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CAM43733.1 - 6.8e-07 29.3 0.0 6.3e-06 26.2 0.0 2.2 1 1 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 CAM43733.1 - 0.0068 16.7 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.18 CAM43733.1 - 0.021 14.3 0.0 0.049 13.2 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B Dynamin_N PF00350.23 CAM43733.1 - 0.057 13.5 1.1 3.2 7.8 0.0 2.6 2 1 1 3 3 3 0 Dynamin family Septin PF00735.18 CAM43733.1 - 0.073 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 CAM43733.1 - 0.15 12.4 0.0 0.49 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain DUF4201 PF13870.6 CAM43734.1 - 0.084 12.6 10.1 0.066 12.9 4.5 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) Sds3 PF08598.11 CAM43734.1 - 0.094 12.7 1.3 0.18 11.8 1.3 1.5 1 0 0 1 1 1 0 Sds3-like DUF4407 PF14362.6 CAM43734.1 - 0.12 11.8 9.7 0.3 10.4 9.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 CAM43734.1 - 0.18 11.9 3.2 0.2 11.8 1.7 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DivIVA PF05103.13 CAM43734.1 - 0.56 10.3 0.1 0.56 10.3 0.1 2.7 2 1 0 3 3 3 0 DivIVA protein BLOC1_2 PF10046.9 CAM43734.1 - 0.56 10.6 4.1 11 6.4 0.4 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YabA PF06156.13 CAM43734.1 - 0.86 10.3 5.0 1.9 9.2 1.0 3.0 3 1 1 4 4 4 0 Initiation control protein YabA HAUS-augmin3 PF14932.6 CAM43734.1 - 1.3 8.6 9.3 1.1 8.8 5.5 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF3138 PF11336.8 CAM43734.1 - 2.7 6.5 5.2 3.5 6.1 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) bZIP_2 PF07716.15 CAM43734.1 - 4.8 7.3 9.3 10 6.3 0.3 3.0 3 0 0 3 3 3 0 Basic region leucine zipper Methyltransf_4 PF02390.17 CAM43735.1 - 2.5e-36 124.7 0.0 3.2e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.6 CAM43735.1 - 0.00076 19.3 0.0 0.0023 17.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAM43735.1 - 0.0021 18.7 0.0 0.014 16.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAM43735.1 - 0.012 16.3 0.0 0.027 15.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF3987 PF13148.6 CAM43735.1 - 0.066 12.2 0.0 0.089 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) ALG11_N PF15924.5 CAM43736.1 - 9.2e-62 208.8 0.1 1.5e-61 208.1 0.1 1.3 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 CAM43736.1 - 2.4e-22 79.3 0.0 3.5e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CAM43736.1 - 4.7e-11 43.3 0.1 7.9e-11 42.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CAM43736.1 - 0.0063 16.9 0.0 0.016 15.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 HALZ PF02183.18 CAM43737.1 - 2.3e-05 24.5 0.8 4e-05 23.8 0.8 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper DivIC PF04977.15 CAM43737.1 - 0.01 15.6 2.5 0.014 15.1 0.6 1.9 2 0 0 2 2 2 0 Septum formation initiator bZIP_1 PF00170.21 CAM43737.1 - 0.037 14.1 1.3 0.083 13.0 0.1 1.9 2 0 0 2 2 2 0 bZIP transcription factor Dpy-30 PF05186.13 CAM43737.1 - 0.061 13.0 0.2 0.16 11.7 0.2 1.7 1 1 0 1 1 1 0 Dpy-30 motif WD40 PF00400.32 CAM43738.1 - 4.3e-09 36.9 7.5 0.0023 18.7 0.1 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat AD PF09793.9 CAM43740.1 - 0.049 13.8 0.0 0.087 13.0 0.0 1.3 1 0 0 1 1 1 0 Anticodon-binding domain 7tm_6 PF02949.20 CAM43741.1 - 0.093 11.8 1.9 0.16 11.0 1.9 1.3 1 0 0 1 1 1 0 7tm Odorant receptor MMR_HSR1_Xtn PF16897.5 CAM43742.1 - 1.2e-36 125.0 1.0 2.1e-36 124.1 1.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 CAM43742.1 - 2.7e-22 78.6 0.1 5.5e-22 77.6 0.1 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 CAM43742.1 - 1.9e-18 66.6 0.0 4.4e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CAM43742.1 - 8.6e-11 41.6 0.0 1.4e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CAM43742.1 - 0.0059 16.7 0.3 1.5 8.8 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Roc PF08477.13 CAM43742.1 - 0.02 15.1 0.1 0.74 10.1 0.0 2.8 2 2 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 CAM43742.1 - 0.091 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 AIG1 family SAC3_GANP PF03399.16 CAM43743.1 - 3.5e-11 43.0 3.3 2e-09 37.3 3.3 2.2 1 1 0 1 1 1 1 SAC3/GANP family FMN_dh PF01070.18 CAM43744.1 - 3.3e-29 102.0 0.1 2.9e-19 69.3 0.1 2.2 2 0 0 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.25 CAM43744.1 - 3.6e-07 29.5 0.7 0.0053 15.8 0.1 2.3 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 CAM43744.1 - 0.00067 18.9 1.3 0.0046 16.2 1.3 2.0 1 1 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 CAM43744.1 - 0.08 12.3 0.2 0.16 11.4 0.2 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase DHO_dh PF01180.21 CAM43744.1 - 0.098 11.8 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.21 CAM43744.1 - 0.36 10.3 2.2 1.2 8.5 0.1 2.3 2 1 1 3 3 3 0 Histidine biosynthesis protein Dynein_heavy PF03028.15 CAM43745.1 - 3.7e-09 36.7 0.0 7.3e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain Ank_2 PF12796.7 CAM43745.1 - 1.5e-08 35.1 0.0 3.9e-08 33.8 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CAM43745.1 - 9e-06 26.1 0.0 0.12 13.0 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CAM43745.1 - 8.9e-05 22.8 0.0 0.0061 17.0 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 CAM43745.1 - 0.017 15.6 0.0 0.31 11.8 0.0 2.8 2 1 0 2 2 2 0 Ankyrin repeat Aa_trans PF01490.18 CAM43746.1 - 6.3e-52 176.6 31.5 7.5e-52 176.4 31.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3850 PF12961.7 CAM43746.1 - 0.024 14.7 0.1 0.057 13.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3850) Aa_trans PF01490.18 CAM43747.1 - 3.5e-50 170.9 38.8 4.4e-50 170.6 38.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CAM43747.1 - 0.00026 20.2 20.5 0.00053 19.1 19.7 1.8 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family DAGK_acc PF00609.19 CAM43748.1 - 8.6e-41 139.9 0.0 1.2e-40 139.5 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 CAM43748.1 - 9.6e-14 51.1 0.0 1.6e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 CAM43748.1 - 0.023 13.9 0.0 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 ATP-NAD kinase HECT PF00632.25 CAM43750.2 - 1e-36 127.0 0.5 3.3e-36 125.3 0.5 1.8 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 CAM43750.2 - 4.8e-16 59.0 0.0 1.5e-07 31.6 0.0 4.8 6 0 0 6 6 6 3 SPRY domain Phage_integrase PF00589.22 CAM43751.1 - 2.5e-06 27.4 0.0 1.8e-05 24.6 0.0 2.5 2 0 0 2 2 2 1 Phage integrase family RVT_1 PF00078.27 CAM43751.1 - 0.0027 17.3 0.0 0.0072 15.9 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A17 PF05380.13 CAM43751.1 - 0.0041 17.1 0.1 0.049 13.6 0.0 2.4 1 1 1 2 2 2 1 Pao retrotransposon peptidase Galactosyl_T PF01762.21 CAM43753.1 - 0.00041 20.2 0.7 0.0023 17.8 0.0 2.5 3 1 1 4 4 4 1 Galactosyltransferase CENP-T_C PF15511.6 CAM43754.1 - 4.5e-05 23.5 0.1 7.2e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CAM43754.1 - 0.002 18.4 0.0 0.0036 17.5 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 CAM43754.1 - 0.0024 18.0 0.1 0.0043 17.2 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 CAM43754.1 - 0.0077 16.6 2.2 0.014 15.8 2.2 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 CAM43754.1 - 0.0082 16.1 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Phage_integrase PF00589.22 CAM43755.1 - 5.7e-06 26.2 0.1 5.5e-05 23.0 0.0 2.8 3 1 0 3 3 3 1 Phage integrase family RVT_1 PF00078.27 CAM43755.1 - 0.0018 17.9 0.0 0.006 16.1 0.0 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A17 PF05380.13 CAM43755.1 - 0.0035 17.4 0.1 0.044 13.8 0.0 2.4 1 1 1 2 2 2 1 Pao retrotransposon peptidase Galactosyl_T PF01762.21 CAM43756.1 - 0.00058 19.7 0.0 0.0026 17.6 0.0 2.1 2 0 0 2 2 2 1 Galactosyltransferase CENP-T_C PF15511.6 CAM43759.1 - 2.6e-05 24.3 0.1 3.8e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 CAM43759.1 - 0.001 19.5 1.0 0.0014 18.9 1.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CAM43759.1 - 0.0011 19.2 0.0 0.0022 18.3 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 CAM43759.1 - 0.0013 18.8 0.1 0.0022 18.1 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 CAM43759.1 - 0.0046 16.9 0.0 0.0074 16.3 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 CAM43759.1 - 0.14 12.2 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Amidohydro_1 PF01979.20 CAM43760.1 - 1.3e-09 37.9 3.0 6.9e-08 32.2 3.0 3.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CAM43760.1 - 5.4e-08 32.7 0.1 0.024 14.1 0.0 2.9 3 0 0 3 3 3 2 Amidohydrolase family PUF PF00806.19 CAM43761.1 - 7.4e-32 107.2 12.6 7.7e-06 25.3 0.1 7.6 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat CPL PF08144.11 CAM43761.1 - 1.5e-05 25.4 1.3 0.98 9.8 0.2 4.3 3 2 0 3 3 3 2 CPL (NUC119) domain TFIIB_C_1 PF18542.1 CAM43761.1 - 0.031 14.3 0.2 0.11 12.5 0.2 2.0 1 0 0 1 1 1 0 Transcription factor IIB C-terminal module 1 IFP_35_N PF07334.13 CAM43761.1 - 0.15 12.2 0.4 4.2 7.5 1.1 2.4 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus SAP PF02037.27 CAM43763.1 - 4.1e-12 45.5 0.1 8.4e-12 44.6 0.1 1.6 1 0 0 1 1 1 1 SAP domain NAM-associated PF14303.6 CAM43763.1 - 0.053 14.2 1.5 0.13 13.0 1.5 1.6 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain ABATE PF07336.11 CAM43763.1 - 0.084 13.5 4.3 1.4 9.6 0.7 2.6 1 1 1 2 2 2 0 Putative stress-induced transcription regulator Menin PF05053.13 CAM43763.1 - 0.21 9.9 1.4 0.25 9.7 1.4 1.1 1 0 0 1 1 1 0 Menin MRI PF15325.6 CAM43763.1 - 1.5 9.9 6.7 1.8 9.7 3.1 2.5 2 0 0 2 2 2 0 Modulator of retrovirus infection TPR_1 PF00515.28 CAM43764.1 - 8.4e-37 123.5 10.7 2.2e-07 30.4 0.1 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 CAM43764.1 - 3e-31 105.0 8.4 4.9e-06 26.3 0.1 6.1 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 CAM43764.1 - 4.9e-21 73.1 7.5 0.001 19.1 0.0 6.2 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 CAM43764.1 - 2.4e-17 62.3 6.3 0.0012 18.5 0.0 5.6 4 2 2 6 6 6 4 TPR repeat TPR_12 PF13424.6 CAM43764.1 - 4.6e-16 58.9 3.6 0.00012 22.3 0.1 4.4 3 1 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 CAM43764.1 - 2.1e-13 49.3 0.8 0.00049 19.9 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 CAM43764.1 - 1.5e-11 44.1 1.0 0.051 14.4 0.0 5.0 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 CAM43764.1 - 1.6e-11 44.6 2.5 0.021 15.5 0.1 4.3 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 CAM43764.1 - 1.5e-10 41.0 2.8 0.026 15.1 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 CAM43764.1 - 3.4e-10 39.6 2.3 0.14 12.6 0.1 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 CAM43764.1 - 1.6e-09 37.3 3.2 0.022 14.6 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CAM43764.1 - 3.6e-09 37.0 1.1 0.1 13.1 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 CAM43764.1 - 2.1e-08 34.2 0.6 0.013 15.6 0.0 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat MIT PF04212.18 CAM43764.1 - 5.4e-06 26.4 12.3 0.081 13.0 0.2 4.4 4 2 0 4 4 4 3 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.9 CAM43764.1 - 9.4e-06 25.0 0.8 0.083 12.4 0.0 4.5 5 0 0 5 5 5 1 SHNi-TPR DUF3856 PF12968.7 CAM43764.1 - 1.2e-05 25.4 3.2 0.05 13.7 0.3 3.3 2 1 0 2 2 2 2 Domain of Unknown Function (DUF3856) ANAPC3 PF12895.7 CAM43764.1 - 2e-05 24.8 1.6 0.086 13.1 0.2 3.2 1 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 Sel1 PF08238.12 CAM43764.1 - 4.4e-05 24.0 4.7 0.36 11.6 0.1 3.7 2 1 1 3 3 3 2 Sel1 repeat SPO22 PF08631.10 CAM43764.1 - 0.0001 21.9 1.0 0.027 14.0 0.3 2.7 3 0 0 3 3 3 1 Meiosis protein SPO22/ZIP4 like TPR_21 PF09976.9 CAM43764.1 - 0.008 15.9 2.3 0.22 11.2 0.4 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat-like domain TAtT PF16811.5 CAM43764.1 - 0.0087 15.4 0.9 2.4 7.4 0.0 2.4 2 1 0 2 2 2 2 TRAP transporter T-component MAS20 PF02064.15 CAM43764.1 - 0.028 14.5 0.7 7.5 6.7 0.0 2.9 1 1 0 2 2 2 0 MAS20 protein import receptor TPR_3 PF07720.12 CAM43764.1 - 0.047 13.7 4.6 0.17 11.9 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF5375 PF17345.2 CAM43764.1 - 0.06 13.2 0.1 0.19 11.6 0.2 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5375) PPR PF01535.20 CAM43764.1 - 0.066 13.5 0.8 31 5.1 0.0 4.0 4 0 0 4 4 3 0 PPR repeat DUF2225 PF09986.9 CAM43764.1 - 0.067 12.9 4.0 1.1 9.0 0.2 3.1 1 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_15 PF13429.6 CAM43764.1 - 0.092 11.9 2.5 4.9 6.3 0.0 3.4 1 1 1 4 4 4 0 Tetratricopeptide repeat CENP-T_C PF15511.6 CAM43765.1 - 4.7e-05 23.5 0.1 8.4e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CAM43765.1 - 0.0022 18.2 0.0 0.004 17.4 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 CAM43765.1 - 0.0024 18.0 0.1 0.0048 17.0 0.1 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 CAM43765.1 - 0.009 16.0 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 CAM43765.1 - 0.01 16.2 1.5 0.018 15.4 1.5 1.4 1 1 0 1 1 1 0 Core histone H2A/H2B/H3/H4 LCM PF04072.14 CAM43767.1 - 4.1e-25 88.8 0.0 1.6e-24 86.9 0.0 1.8 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase T6SS_TssG PF06996.11 CAM43768.1 - 0.027 13.7 0.1 0.064 12.5 0.1 1.5 1 0 0 1 1 1 0 Type VI secretion, TssG IMS PF00817.20 CAM43769.2 - 1.8e-34 118.9 0.0 3.6e-34 117.9 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 CAM43769.2 - 0.043 14.5 0.0 0.12 13.1 0.0 1.7 1 1 0 1 1 1 0 impB/mucB/samB family C-terminal domain Acetyltransf_8 PF13523.6 CAM43770.1 - 0.08 12.6 0.4 0.34 10.6 0.0 2.3 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain DUF520 PF04461.13 CAM43770.1 - 0.098 12.8 0.2 0.36 10.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF520) Pox_MCEL PF03291.16 CAM43771.1 - 1.7e-35 122.7 0.0 1.2e-34 119.9 0.0 1.9 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_23 PF13489.6 CAM43771.1 - 8.6e-05 22.4 0.0 0.00032 20.6 0.0 1.9 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAM43771.1 - 0.0016 19.1 0.0 0.0071 17.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 CAM43771.1 - 0.0023 17.1 0.0 0.077 12.2 0.0 2.1 2 0 0 2 2 2 1 NNMT/PNMT/TEMT family Methyltransf_12 PF08242.12 CAM43771.1 - 0.028 15.1 0.0 0.11 13.2 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 CAM43771.1 - 0.032 14.0 0.0 0.23 11.3 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain PUB PF09409.10 CAM43772.1 - 5.7e-17 61.4 0.0 1.8e-16 59.9 0.0 1.8 2 0 0 2 2 2 1 PUB domain Dodecin PF07311.12 CAM43772.1 - 0.018 15.3 0.3 0.064 13.5 0.1 2.1 2 0 0 2 2 2 0 Dodecin DUF4706 PF15797.5 CAM43772.1 - 2.8 8.5 7.1 4.8 7.8 6.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4706) Borrelia_orfA PF02414.15 CAM43772.1 - 4.4 6.9 7.9 6.3 6.4 7.9 1.1 1 0 0 1 1 1 0 Borrelia ORF-A DUF572 PF04502.13 CAM43772.1 - 6.9 6.2 13.3 11 5.5 13.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) HEAT PF02985.22 CAM43773.1 - 0.054 13.8 0.0 3.5 8.1 0.0 3.2 2 0 0 2 2 2 0 HEAT repeat His_Phos_1 PF00300.22 CAM43774.1 - 2.7e-26 92.5 0.0 1.5e-25 90.1 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_24 PF13479.6 CAM43774.1 - 0.23 11.1 0.0 0.39 10.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain EFG_C PF00679.24 CAM43777.1 - 8.2e-21 73.8 0.0 1.2e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 CAM43777.1 - 2e-16 59.9 0.0 2.8e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU PF00009.27 CAM43778.1 - 1.5e-64 217.2 0.5 1.8e-64 216.9 0.5 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CAM43778.1 - 0.0002 21.4 0.0 0.00039 20.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CAM43778.1 - 0.035 13.6 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 CAM43778.1 - 0.043 13.9 0.4 3.7 7.6 0.0 2.5 1 1 2 3 3 3 0 Dynamin family GTP_EFTU PF00009.27 CAM43779.1 - 5.4e-65 218.6 0.4 8.6e-65 217.9 0.4 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CAM43779.1 - 4.7e-29 100.6 0.0 1.3e-28 99.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CAM43779.1 - 4.9e-20 71.4 0.0 1.7e-19 69.6 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.6 CAM43779.1 - 6.2e-14 51.9 0.0 3.1e-13 49.6 0.0 2.1 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 CAM43779.1 - 6e-13 49.0 0.1 1.6e-12 47.6 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CAM43779.1 - 0.0021 18.1 0.1 0.0052 16.9 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Peptidase_S24 PF00717.23 CAM43780.1 - 6.5e-07 29.2 0.0 1.1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 CAM43780.1 - 0.0067 16.2 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 SET PF00856.28 CAM43781.1 - 3.7e-09 37.2 0.1 1.8e-07 31.7 0.1 2.3 1 1 0 1 1 1 1 SET domain RimK PF08443.11 CAM43781.1 - 0.039 13.6 0.0 0.064 12.8 0.0 1.2 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Glycos_transf_2 PF00535.26 CAM43782.1 - 8.1e-31 107.1 0.0 1e-30 106.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CAM43782.1 - 7e-05 22.8 0.0 0.0001 22.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF2606 PF10794.9 CAM43782.1 - 0.0056 16.4 0.0 0.009 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2606) DAO PF01266.24 CAM43782.1 - 0.17 11.5 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FKBP_C PF00254.28 CAM43783.1 - 3.4e-27 94.6 0.0 4.3e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF4164 PF13747.6 CAM43784.2 - 1.6e-05 25.1 4.0 1.6e-05 25.1 4.0 2.6 2 1 1 3 3 3 1 Domain of unknown function (DUF4164) ADIP PF11559.8 CAM43784.2 - 1.9e-05 24.8 10.5 1.9e-05 24.8 10.5 1.9 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.9 CAM43784.2 - 0.00011 22.2 13.6 0.00011 22.2 13.6 1.9 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 CAM43784.2 - 0.00021 21.3 19.2 0.0008 19.5 13.1 2.7 2 1 1 3 3 3 2 TPR/MLP1/MLP2-like protein CEP63 PF17045.5 CAM43784.2 - 0.0008 19.4 10.2 0.0008 19.4 10.2 1.5 2 0 0 2 2 2 1 Centrosomal protein of 63 kDa KASH_CCD PF14662.6 CAM43784.2 - 0.0029 17.5 17.7 0.0058 16.5 16.1 1.9 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH Phage_GP20 PF06810.11 CAM43784.2 - 0.0039 17.0 5.3 0.0069 16.2 5.3 1.3 1 0 0 1 1 1 1 Phage minor structural protein GP20 GldM_N PF12081.8 CAM43784.2 - 0.0066 16.6 1.8 0.012 15.7 1.8 1.4 1 0 0 1 1 1 1 GldM N-terminal domain Golgin_A5 PF09787.9 CAM43784.2 - 0.012 15.0 11.0 0.014 14.9 8.5 1.8 2 0 0 2 2 2 0 Golgin subfamily A member 5 STAT_alpha PF01017.20 CAM43784.2 - 0.015 15.2 8.4 0.028 14.3 8.4 1.5 1 0 0 1 1 1 0 STAT protein, all-alpha domain bZIP_1 PF00170.21 CAM43784.2 - 0.016 15.3 0.5 0.016 15.3 0.5 3.2 2 2 2 4 4 3 0 bZIP transcription factor FlaC_arch PF05377.11 CAM43784.2 - 0.037 14.4 0.4 0.037 14.4 0.4 2.6 2 1 0 3 3 2 0 Flagella accessory protein C (FlaC) ATG16 PF08614.11 CAM43784.2 - 0.037 14.3 18.9 0.092 13.0 12.9 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) V_ATPase_I PF01496.19 CAM43784.2 - 0.04 11.8 1.9 0.037 12.0 1.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.9 CAM43784.2 - 0.043 12.9 16.7 0.015 14.4 10.2 2.3 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 FapA PF03961.13 CAM43784.2 - 0.055 12.1 4.7 0.081 11.5 4.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A YabA PF06156.13 CAM43784.2 - 0.06 14.0 13.5 1.1 9.9 3.9 2.7 2 1 1 3 3 2 0 Initiation control protein YabA DUF1664 PF07889.12 CAM43784.2 - 0.069 13.2 4.3 0.14 12.2 4.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) RskA PF10099.9 CAM43784.2 - 0.07 13.4 1.8 0.093 13.0 1.8 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA COG5 PF10392.9 CAM43784.2 - 0.095 12.9 5.7 0.057 13.6 2.7 1.9 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Seryl_tRNA_N PF02403.22 CAM43784.2 - 0.14 12.4 13.8 0.03 14.6 8.4 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Spectrin PF00435.21 CAM43784.2 - 0.15 12.6 10.8 0.041 14.4 5.9 2.3 2 1 0 2 2 2 0 Spectrin repeat HemX PF04375.14 CAM43784.2 - 0.17 11.2 9.6 0.022 14.1 4.8 1.7 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Spc7 PF08317.11 CAM43784.2 - 0.18 10.6 14.2 0.061 12.2 11.1 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4250 PF14056.6 CAM43784.2 - 0.28 11.2 2.0 7.2 6.6 0.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4250) HAUS-augmin3 PF14932.6 CAM43784.2 - 0.41 10.2 12.3 0.094 12.3 8.2 1.9 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Sec34 PF04136.15 CAM43784.2 - 0.52 10.2 9.3 0.37 10.7 4.9 2.5 2 1 1 3 3 3 0 Sec34-like family FliJ PF02050.16 CAM43784.2 - 0.56 10.4 15.9 0.076 13.2 8.8 2.3 2 0 0 2 2 2 0 Flagellar FliJ protein AKNA PF12443.8 CAM43784.2 - 0.66 10.7 9.2 0.41 11.3 4.6 2.7 2 1 0 2 2 2 0 AT-hook-containing transcription factor DUF2968 PF11180.8 CAM43784.2 - 0.76 9.4 18.4 0.2 11.3 11.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DUF4446 PF14584.6 CAM43784.2 - 0.86 9.6 4.8 0.22 11.5 1.4 1.7 2 1 0 2 2 1 0 Protein of unknown function (DUF4446) ZapB PF06005.12 CAM43784.2 - 0.96 9.9 21.8 1.3 9.5 10.2 3.4 2 1 1 3 3 3 0 Cell division protein ZapB Nup88 PF10168.9 CAM43784.2 - 1.1 6.9 10.3 1.6 6.5 10.3 1.1 1 0 0 1 1 1 0 Nuclear pore component SOGA PF11365.8 CAM43784.2 - 1.3 10.2 15.2 0.51 11.5 11.5 2.2 2 1 0 2 2 1 0 Protein SOGA APG6_N PF17675.1 CAM43784.2 - 1.4 9.4 21.4 3.6 8.1 16.0 2.7 2 1 0 2 2 2 0 Apg6 coiled-coil region CENP-H PF05837.12 CAM43784.2 - 1.5 9.3 14.0 1.3 9.4 9.1 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Swi5 PF07061.11 CAM43784.2 - 1.6 8.9 8.8 1.7 8.7 4.7 2.7 2 1 0 2 2 2 0 Swi5 COG2 PF06148.11 CAM43784.2 - 1.7 8.7 9.2 0.67 10.0 6.4 1.9 2 0 0 2 2 1 0 COG (conserved oligomeric Golgi) complex component, COG2 UPF0242 PF06785.11 CAM43784.2 - 1.9 8.5 10.8 0.92 9.6 8.2 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Jnk-SapK_ap_N PF09744.9 CAM43784.2 - 2.2 8.5 18.0 3.9 7.7 13.9 2.5 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 YlqD PF11068.8 CAM43784.2 - 2.7 8.4 13.1 1.8 9.0 10.0 1.9 2 0 0 2 2 2 0 YlqD protein ApoO PF09769.9 CAM43784.2 - 3.7 7.5 5.5 0.41 10.6 0.6 1.8 2 0 0 2 2 2 0 Apolipoprotein O DivIC PF04977.15 CAM43784.2 - 3.9 7.3 17.7 0.22 11.3 4.8 3.3 2 1 1 3 3 3 0 Septum formation initiator Fungal_TACC PF12709.7 CAM43784.2 - 4.6 7.8 11.0 1.1 9.8 2.5 2.8 2 1 0 3 3 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins PRKG1_interact PF15898.5 CAM43784.2 - 5.5 7.9 18.5 2 9.4 13.4 2.1 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain TMPIT PF07851.13 CAM43784.2 - 6.7 5.9 11.5 0.66 9.2 7.3 1.4 2 0 0 2 2 1 0 TMPIT-like protein DUF3450 PF11932.8 CAM43784.2 - 7.7 5.7 16.9 0.12 11.7 3.7 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) GAS PF13851.6 CAM43784.2 - 8.3 5.7 18.3 4.5 6.6 14.7 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Paf67 PF10255.9 CAM43785.1 - 1.3e-49 169.3 0.0 2.7e-49 168.3 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase I-associated factor PAF67 HEPPP_synt_1 PF07307.11 CAM43785.1 - 0.12 12.0 0.1 1.9 8.0 0.1 2.3 2 0 0 2 2 2 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 FGGY_N PF00370.21 CAM43786.2 - 1.1e-12 48.0 0.0 1.4e-12 47.7 0.0 1.0 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain CH PF00307.31 CAM43787.2 - 0.00033 20.8 0.0 1.1 9.5 0.0 3.0 3 0 0 3 3 3 2 Calponin homology (CH) domain TFIIS_M PF07500.14 CAM43788.1 - 5.3e-07 30.1 0.2 8.5e-07 29.4 0.2 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain NUDIX PF00293.28 CAM43790.1 - 3.5e-14 53.0 0.0 5.1e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain ESCRT-II PF05871.12 CAM43791.1 - 1.5e-12 47.9 0.0 8e-12 45.6 0.0 1.9 1 1 0 1 1 1 1 ESCRT-II complex subunit DUF3223 PF11523.8 CAM43791.1 - 0.048 14.5 0.5 4.3 8.3 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3223) Proteasome PF00227.26 CAM43792.1 - 8e-29 100.5 0.0 9.7e-29 100.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit RNase_HII PF01351.18 CAM43794.1 - 1.5e-18 67.4 0.0 4.7e-10 39.6 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease HII Nop10p PF04135.12 CAM43795.1 - 3.1e-21 75.1 0.5 4e-21 74.8 0.5 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family IQ PF00612.27 CAM43796.1 - 0.016 14.9 1.3 0.086 12.7 1.3 2.2 1 0 0 1 1 1 0 IQ calmodulin-binding motif EMC3_TMCO1 PF01956.16 CAM43797.1 - 2.2e-46 157.7 1.9 2.9e-46 157.3 1.9 1.2 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like PIP5K PF01504.18 CAM43798.1 - 6e-62 209.4 0.0 1.1e-61 208.5 0.0 1.4 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Spore_coat_CotO PF14153.6 CAM43799.1 - 0.003 17.5 1.3 0.0036 17.3 1.3 1.1 1 0 0 1 1 1 1 Spore coat protein CotO Med3 PF11593.8 CAM43800.1 - 3.2e-05 23.3 9.5 3.2e-05 23.3 9.5 2.2 2 0 0 2 2 2 1 Mediator complex subunit 3 fungal DB_JBP1 PF18526.1 CAM43800.1 - 0.0037 17.2 0.0 0.0074 16.3 0.0 1.5 1 0 0 1 1 1 1 Thymine dioxygenase JBP1 DNA-binding domain Spore_coat_CotO PF14153.6 CAM43800.1 - 0.012 15.5 4.5 0.023 14.7 4.5 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Macoilin PF09726.9 CAM43800.1 - 0.2 10.2 7.7 0.24 9.9 7.7 1.1 1 0 0 1 1 1 0 Macoilin family Pex14_N PF04695.13 CAM43800.1 - 0.63 10.7 15.7 2.3 8.8 15.7 2.1 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PI3K_1B_p101 PF10486.9 CAM43800.1 - 0.89 7.2 10.8 1.3 6.7 10.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF4614 PF15391.6 CAM43800.1 - 3.8 7.5 18.0 6.8 6.6 18.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) SPX PF03105.19 CAM43800.1 - 4.1 7.2 16.6 6.1 6.7 16.6 1.2 1 0 0 1 1 1 0 SPX domain Ndc1_Nup PF09531.10 CAM43800.1 - 6.7 5.3 12.7 9.4 4.8 12.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PDZ_2 PF13180.6 CAM43801.2 - 0.00023 21.4 0.0 0.00059 20.1 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CAM43801.2 - 0.011 16.1 0.1 0.029 14.7 0.1 1.7 1 0 0 1 1 1 0 PDZ domain YgaB PF14182.6 CAM43801.2 - 3.9 7.9 7.6 0.41 11.1 1.6 2.4 2 1 1 3 3 3 0 YgaB-like protein ArnB_C PF18677.1 CAM43802.1 - 0.014 15.5 3.3 0.032 14.3 3.3 1.6 1 0 0 1 1 1 0 Archaellum regulatory network B, C-terminal domain HrpB1_HrpK PF09613.10 CAM43802.1 - 0.064 12.9 0.1 0.13 11.9 0.1 1.7 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) MIF PF01187.18 CAM43802.1 - 0.082 13.2 0.1 0.24 11.7 0.0 1.8 2 0 0 2 2 2 0 Macrophage migration inhibitory factor (MIF) Aa_trans PF01490.18 CAM43803.1 - 1.9e-60 204.7 23.9 2.2e-60 204.5 23.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CAM43803.1 - 1.1e-08 34.6 16.1 1.1e-08 34.6 16.1 1.8 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family TFIIA_gamma_C PF02751.14 CAM43804.1 - 0.00057 20.0 0.0 0.00092 19.3 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit W2 PF02020.18 CAM43805.1 - 0.049 13.8 0.2 1.2 9.3 0.0 2.6 2 0 0 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon Sec1 PF00995.23 CAM43807.2 - 8.2e-101 339.0 0.4 1e-100 338.7 0.4 1.1 1 0 0 1 1 1 1 Sec1 family Ppx-GppA PF02541.16 CAM43807.2 - 0.1 12.0 0.2 0.35 10.3 0.1 1.8 2 0 0 2 2 2 0 Ppx/GppA phosphatase family Dus PF01207.17 CAM43808.1 - 3e-36 125.1 0.2 7.1e-32 110.7 0.0 2.2 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-ANAPC11 PF12861.7 CAM43809.1 - 0.021 14.9 0.8 0.039 14.0 0.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C2HC_2 PF13913.6 CAM43810.1 - 2.1e-16 59.4 6.3 9.5e-10 38.1 1.3 2.3 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.6 CAM43810.1 - 0.1 13.1 0.2 14 6.4 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double domain FAM76 PF16046.5 CAM43810.1 - 0.19 11.0 0.4 0.28 10.5 0.4 1.2 1 0 0 1 1 1 0 FAM76 protein zf-C2H2_4 PF13894.6 CAM43810.1 - 0.21 12.5 3.3 20 6.4 1.5 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CAM43810.1 - 0.25 11.4 3.5 3 7.9 0.2 2.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CAM43810.1 - 0.26 11.8 2.7 15 6.3 1.3 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Sgf11 PF08209.11 CAM43810.1 - 0.27 10.8 3.2 6.5 6.4 1.1 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) ADK_lid PF05191.14 CAM43810.1 - 0.5 10.4 3.7 2.3 8.3 0.5 2.3 2 0 0 2 2 2 0 Adenylate kinase, active site lid DnaJ PF00226.31 CAM43811.2 - 2.4e-21 75.6 1.6 6.4e-20 71.1 0.4 2.6 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.17 CAM43811.2 - 6.2e-15 54.0 27.2 0.0001 22.1 0.1 7.8 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 CAM43811.2 - 2.2e-11 44.1 19.4 0.0027 18.2 2.0 6.0 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 CAM43811.2 - 7.8e-10 38.8 9.7 0.00041 20.4 0.2 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 CAM43811.2 - 2.8e-09 36.4 27.9 0.0017 18.1 0.2 7.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 CAM43811.2 - 3e-08 33.8 25.8 0.013 16.2 0.0 7.9 6 1 2 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 CAM43811.2 - 3.6e-06 26.6 6.4 0.00037 20.1 0.6 5.3 6 2 1 7 7 6 2 TPR repeat TPR_12 PF13424.6 CAM43811.2 - 9.7e-05 22.6 20.6 0.0015 18.8 1.3 5.8 3 2 3 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 CAM43811.2 - 0.00011 22.8 28.2 0.00016 22.3 4.0 6.2 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 CAM43811.2 - 0.00047 20.2 22.3 0.26 11.6 0.2 6.5 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 CAM43811.2 - 0.00099 19.3 0.3 0.00099 19.3 0.3 6.5 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 CAM43811.2 - 0.0025 17.6 0.4 0.0025 17.6 0.4 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CAM43811.2 - 0.0029 17.8 13.7 0.0061 16.8 0.3 4.2 2 2 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CAM43811.2 - 0.0041 17.0 9.5 8.1 6.7 0.2 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CAM43811.2 - 0.081 13.0 5.2 1.4 9.0 0.4 4.1 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat DUF5385 PF17359.2 CAM43811.2 - 0.16 11.5 4.1 0.66 9.5 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5385) DUF2408 PF10303.9 CAM43811.2 - 3.5 8.2 6.9 5.5 7.6 1.4 2.7 2 1 1 3 3 2 0 Protein of unknown function (DUF2408) TPR_20 PF14561.6 CAM43811.2 - 7.8 6.9 12.6 0.25 11.7 0.5 3.9 3 3 2 5 5 5 0 Tetratricopeptide repeat Mito_carr PF00153.27 CAM43812.1 - 1e-87 288.2 18.8 1.7e-20 72.7 0.0 6.2 5 1 1 6 6 6 6 Mitochondrial carrier protein Serine_protease PF18405.1 CAM43812.1 - 0.00086 18.5 4.8 1.4 8.0 0.0 4.2 5 0 0 5 5 5 3 Gammaproteobacterial serine protease PP2C PF00481.21 CAM43814.1 - 1.1e-68 231.6 0.6 1.4e-68 231.3 0.6 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CAM43814.1 - 0.0028 17.3 0.1 0.0047 16.6 0.1 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CAM43814.1 - 0.021 14.8 0.1 0.9 9.4 0.0 2.3 2 1 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) LSM PF01423.22 CAM43815.1 - 6.2e-07 29.0 0.2 9.4e-07 28.4 0.2 1.3 1 0 0 1 1 1 1 LSM domain DUF5623 PF18536.1 CAM43816.1 - 0.01 16.1 0.0 0.021 15.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) ubiquitin PF00240.23 CAM43817.1 - 5.9e-16 58.0 0.1 1.1e-15 57.1 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 CAM43817.1 - 4.5e-06 26.4 0.8 1.2e-05 25.1 0.8 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 CAM43817.1 - 2.9e-05 23.8 0.1 5.4e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CAM43817.1 - 0.0075 16.7 0.0 0.024 15.1 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain RPN13_C PF16550.5 CAM43817.1 - 0.0086 16.2 9.7 0.038 14.2 1.8 2.7 3 0 0 3 3 3 2 UCH-binding domain ComX PF05952.12 CAM43817.1 - 0.017 15.0 4.4 0.024 14.6 2.8 2.1 2 0 0 2 2 2 0 Bacillus competence pheromone ComX Rad60-SLD_2 PF13881.6 CAM43817.1 - 0.077 13.1 0.2 0.21 11.7 0.2 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CAM43817.1 - 0.087 13.4 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain HOIP-UBA PF16678.5 CAM43817.1 - 0.088 12.8 0.6 0.32 11.0 0.1 2.0 2 0 0 2 2 2 0 HOIP UBA domain pair Ubiquitin_5 PF18037.1 CAM43817.1 - 0.092 13.1 0.2 0.092 13.1 0.2 1.6 2 0 0 2 2 2 0 Ubiquitin-like domain XPC-binding PF09280.11 CAM43817.1 - 0.36 10.6 21.4 0.14 11.9 17.6 2.3 2 0 0 2 2 2 0 XPC-binding domain GerD PF17898.1 CAM43817.1 - 0.68 9.9 17.2 1.5 8.8 16.0 2.1 2 1 1 3 3 3 0 Spore germination GerD central core domain Pkinase PF00069.25 CAM43818.1 - 6.2e-79 265.1 0.0 7.1e-79 264.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM43818.1 - 4.8e-36 124.4 0.0 1.1e-35 123.1 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 CAM43818.1 - 0.0024 17.8 0.7 0.069 13.1 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CAM43818.1 - 0.0062 15.5 0.0 0.034 13.1 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain YabA PF06156.13 CAM43819.2 - 1.4 9.6 18.5 0.9 10.2 2.7 3.6 2 1 1 3 3 3 0 Initiation control protein YabA Sec20 PF03908.13 CAM43819.2 - 4.3 7.3 7.9 1.1 9.2 0.4 3.0 2 1 1 3 3 3 0 Sec20 ADIP PF11559.8 CAM43819.2 - 5.9 7.0 39.0 1.4 8.9 4.0 4.4 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Lectin_N PF03954.14 CAM43819.2 - 6 6.6 14.6 2.3 8.0 2.7 3.1 1 1 1 3 3 3 0 Hepatic lectin, N-terminal domain GTP_EFTU PF00009.27 CAM43820.1 - 4.8e-62 209.0 0.0 7.6e-62 208.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 CAM43820.1 - 8.3e-24 83.5 0.0 1.9e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 CAM43820.1 - 6.3e-21 74.2 0.1 1.4e-20 73.1 0.1 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 CAM43820.1 - 3.8e-18 65.4 0.0 8.7e-18 64.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 CAM43820.1 - 2.6e-07 30.9 0.0 8.7e-07 29.2 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CAM43820.1 - 2e-05 24.5 0.0 7.7e-05 22.5 0.0 2.0 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 CAM43820.1 - 0.0028 17.7 0.0 0.0061 16.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF4132 PF13569.6 CAM43820.1 - 0.0066 16.3 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4132) AIG1 PF04548.16 CAM43820.1 - 0.036 13.4 0.0 0.073 12.4 0.0 1.4 1 0 0 1 1 1 0 AIG1 family DUF442 PF04273.13 CAM43820.1 - 0.052 13.6 0.0 0.82 9.8 0.0 2.4 2 0 0 2 2 2 0 Putative phosphatase (DUF442) DUF148 PF02520.17 CAM43820.1 - 0.065 13.3 0.1 0.15 12.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF148 IF4E PF01652.18 CAM43823.1 - 1.3e-09 38.0 0.0 1.6e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Ribosomal_S27 PF01599.19 CAM43824.1 - 1e-22 80.0 4.2 1.9e-22 79.2 4.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.23 CAM43824.1 - 2.6e-09 36.7 0.3 2.8e-08 33.4 0.0 2.4 2 1 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 CAM43824.1 - 1.6e-05 24.6 0.4 0.00026 20.8 0.0 2.4 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.21 CAM43824.1 - 0.0068 16.6 0.7 0.011 15.9 0.7 1.4 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain DnaJ PF00226.31 CAM43825.1 - 1.1e-21 76.7 0.4 1.1e-21 76.7 0.4 1.6 2 0 0 2 2 2 1 DnaJ domain ATP-synt_Eps PF04627.13 CAM43826.1 - 1.2e-06 28.4 0.1 3e-06 27.1 0.1 1.6 1 1 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain DUF3592 PF12158.8 CAM43827.1 - 2.6e-20 73.0 0.7 3.1e-20 72.8 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3592) RNase_HII PF01351.18 CAM43828.2 - 2.2e-40 138.6 0.0 2.7e-40 138.3 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII PIG-U PF06728.13 CAM43829.1 - 2.5e-07 30.1 18.9 1.3e-05 24.5 18.9 2.5 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U UAA PF08449.11 CAM43831.1 - 3.8e-07 29.6 11.2 6e-05 22.4 0.1 2.4 3 0 0 3 3 3 2 UAA transporter family EamA PF00892.20 CAM43831.1 - 5.3e-07 29.9 29.6 0.00028 21.1 6.0 4.0 4 1 0 4 4 4 3 EamA-like transporter family SLC35F PF06027.12 CAM43831.1 - 5.6e-06 26.1 0.1 5.6e-06 26.1 0.1 2.5 3 0 0 3 3 3 2 Solute carrier family 35 CRT-like PF08627.10 CAM43831.1 - 0.0012 17.8 11.9 0.0082 15.1 11.9 2.0 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like SSB PF00436.25 CAM43834.1 - 1.7e-05 24.8 0.1 2.5e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Single-strand binding protein family LRR_9 PF14580.6 CAM43835.1 - 6.9e-14 51.7 0.1 3.6e-13 49.4 0.1 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 CAM43835.1 - 3.6e-08 33.6 0.1 0.021 15.3 0.0 3.1 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM43835.1 - 1.1e-07 31.5 0.2 1.6e-06 27.7 0.2 2.6 1 1 0 2 2 2 1 Leucine rich repeat Pkinase PF00069.25 CAM43836.1 - 1.3e-70 237.8 0.0 1.7e-70 237.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM43836.1 - 4.5e-35 121.2 0.0 6.3e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM43836.1 - 0.00012 21.5 0.0 0.0002 20.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CAM43836.1 - 0.00022 20.6 2.2 0.00041 19.8 2.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CAM43836.1 - 0.0091 15.0 2.2 0.024 13.6 2.2 1.7 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CAM43836.1 - 0.035 14.0 0.0 0.083 12.8 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CAM43836.1 - 0.045 12.5 1.7 0.06 12.1 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase FeoB_N PF02421.18 CAM43836.1 - 0.091 12.3 0.3 0.19 11.3 0.3 1.5 1 1 0 1 1 1 0 Ferrous iron transport protein B Torus PF16131.5 CAM43837.2 - 2.3e-06 28.2 6.5 0.00071 20.2 0.2 3.2 3 0 0 3 3 3 2 Torus domain zf-CCCH_4 PF18044.1 CAM43837.2 - 0.0039 17.0 2.8 0.0039 17.0 2.8 4.0 4 0 0 4 4 4 2 CCCH-type zinc finger zf-CCCH PF00642.24 CAM43837.2 - 0.047 13.6 19.1 0.06 13.3 0.4 4.1 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CAM43838.2 - 2.2e-06 28.3 5.2 0.00017 22.3 0.1 3.1 3 0 0 3 3 3 2 Torus domain zf-CCCH_4 PF18044.1 CAM43838.2 - 0.0012 18.6 1.8 0.0026 17.5 1.8 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CAM43838.2 - 0.0075 16.3 1.2 0.0075 16.3 1.2 2.4 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 CAM43838.2 - 1.4 8.9 5.1 0.44 10.5 1.1 2.1 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) XPC-binding PF09280.11 CAM43839.1 - 3.1e-06 26.8 0.0 7.6e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 XPC-binding domain Plasmid_RAQPRD PF09686.10 CAM43839.1 - 0.023 14.9 0.1 0.08 13.2 0.1 2.0 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Na_trans_assoc PF06512.13 CAM43839.1 - 0.31 11.3 2.6 0.65 10.2 2.6 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated TPR_1 PF00515.28 CAM43840.2 - 6.2e-13 48.0 0.1 0.0021 17.8 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 CAM43840.2 - 1.9e-08 33.8 26.5 0.064 13.4 0.0 7.6 8 0 0 8 8 8 3 Tetratricopeptide repeat DnaJ PF00226.31 CAM43840.2 - 1.4e-07 31.5 0.1 3.2e-07 30.4 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain TPR_11 PF13414.6 CAM43840.2 - 2e-07 30.6 2.2 0.047 13.4 0.2 4.5 4 0 0 4 4 4 2 TPR repeat TPR_7 PF13176.6 CAM43840.2 - 5.1e-05 23.0 3.5 0.42 10.8 0.1 4.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CAM43840.2 - 9.3e-05 22.3 4.6 3.3 8.2 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 CAM43840.2 - 0.0021 18.2 31.8 0.42 10.8 0.7 6.2 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 CAM43840.2 - 0.016 15.5 2.5 17 6.0 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 CAM43840.2 - 0.021 15.1 2.3 0.021 15.1 2.3 4.6 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 CAM43840.2 - 0.21 12.3 43.5 1.3 9.8 1.6 6.2 5 1 2 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 CAM43840.2 - 0.72 10.8 35.1 0.33 11.9 0.6 7.2 6 1 1 7 7 7 0 Tetratricopeptide repeat CDC50 PF03381.15 CAM43841.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 LEM3 (ligand-effect modulator 3) family / CDC50 family Peptidase_C2 PF00648.21 CAM43842.1 - 1.4e-22 80.1 0.0 2e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease MEDS PF14417.6 CAM43842.1 - 0.24 11.2 2.4 3.2 7.6 0.1 3.0 3 0 0 3 3 3 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Tfb2 PF03849.14 CAM43844.1 - 1.5e-22 80.1 0.0 2e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.6 CAM43844.1 - 1.7e-06 28.2 0.3 6.9e-06 26.2 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Tfb2_C PF18307.1 CAM43844.1 - 0.04 14.3 0.5 0.22 12.0 0.3 2.1 2 0 0 2 2 2 0 Transcription factor Tfb2 (p52) C-terminal domain rOmpB PF12334.8 CAM43845.1 - 0.076 12.5 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Rickettsia outer membrane protein B Arf PF00025.21 CAM43846.1 - 2e-31 108.8 0.0 2.8e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CAM43846.1 - 2.6e-09 36.9 0.0 4.3e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAM43846.1 - 6.7e-09 36.0 0.0 1.2e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CAM43846.1 - 1e-08 34.8 0.0 1.6e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CAM43846.1 - 5.2e-08 32.4 0.0 3.1e-07 29.9 0.0 2.0 1 1 1 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.27 CAM43846.1 - 0.014 14.9 0.0 0.026 14.1 0.0 1.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain cNMP_binding PF00027.29 CAM43847.2 - 3.2e-17 62.4 2.0 6.7e-10 38.9 0.1 5.7 7 0 0 7 7 7 2 Cyclic nucleotide-binding domain C2 PF00168.30 CAM43847.2 - 1.7e-07 31.5 0.0 0.0053 17.0 0.0 4.8 6 0 0 6 6 6 2 C2 domain Torus PF16131.5 CAM43848.1 - 3.7e-06 27.6 5.7 0.00044 20.9 0.1 2.8 3 0 0 3 3 3 2 Torus domain zf_CCCH_4 PF18345.1 CAM43848.1 - 6.8 6.9 14.1 0.21 11.7 0.8 3.2 3 0 0 3 3 3 0 Zinc finger domain ABC_tran_CTD PF16326.5 CAM43849.1 - 0.013 15.7 2.0 0.013 15.7 2.0 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF4407 PF14362.6 CAM43849.1 - 0.12 11.7 10.9 0.21 10.9 10.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 CAM43849.1 - 0.27 11.0 7.3 0.31 10.8 1.0 2.4 2 0 0 2 2 2 0 Septum formation initiator TMF_DNA_bd PF12329.8 CAM43849.1 - 0.48 10.5 7.1 4.3 7.4 2.2 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding WDCP PF15390.6 CAM43849.1 - 0.96 7.7 7.3 1.4 7.2 7.3 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family ATG16 PF08614.11 CAM43849.1 - 1.7 8.8 23.2 0.9 9.7 9.1 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) ZapB PF06005.12 CAM43849.1 - 3.9 8.0 9.2 3.7 8.1 1.2 2.4 2 0 0 2 2 2 0 Cell division protein ZapB DUF4686 PF15742.5 CAM43849.1 - 4 6.5 17.6 15 4.6 17.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4686) Exonuc_VII_L PF02601.15 CAM43849.1 - 6.4 6.3 10.9 11 5.5 10.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Pkinase PF00069.25 CAM43850.2 - 3.1e-55 187.4 0.0 4e-55 187.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM43850.2 - 6.7e-31 107.5 0.0 9.4e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAM43850.2 - 0.00063 18.6 0.0 0.00099 18.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CAM43850.2 - 0.0025 17.8 0.3 0.64 9.9 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CAM43850.2 - 0.16 11.3 0.0 0.35 10.1 0.0 1.5 2 0 0 2 2 2 0 Kinase-like HA2 PF04408.23 CAM43851.1 - 3.7e-17 62.6 0.0 1.1e-16 61.1 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CAM43851.1 - 2.5e-15 56.8 0.0 8.3e-15 55.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CAM43851.1 - 4e-09 36.5 0.0 9e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 CAM43851.1 - 3.3e-06 27.4 0.0 9.5e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold T2SSE PF00437.20 CAM43851.1 - 0.00029 20.0 0.0 0.00063 18.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 CAM43851.1 - 0.0017 18.6 0.2 0.017 15.4 0.2 2.6 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 CAM43851.1 - 0.0026 17.9 0.0 0.4 10.8 0.0 2.9 2 0 0 2 2 2 1 Sigma-54 interaction domain ATPase PF06745.13 CAM43851.1 - 0.014 14.7 0.0 0.031 13.6 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.6 CAM43851.1 - 0.017 15.4 0.0 0.059 13.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 CAM43851.1 - 0.056 12.9 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein cobW PF02492.19 CAM43851.1 - 0.063 12.9 0.1 2.3 7.8 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 CAM43851.1 - 0.083 13.4 0.0 0.2 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CAM43851.1 - 0.1 12.1 0.0 0.29 10.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 CAM43851.1 - 0.14 12.1 0.0 0.6 10.0 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 CAM43851.1 - 0.14 12.6 0.0 0.38 11.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 CAM43851.1 - 0.15 11.9 0.0 0.65 9.9 0.0 2.1 2 0 0 2 2 2 0 NACHT domain ResIII PF04851.15 CAM43851.1 - 0.19 11.7 0.0 4.8 7.1 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NifU PF01106.17 CAM43852.1 - 1.8e-24 85.7 0.1 2.9e-24 85.0 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.11 CAM43852.1 - 9.3e-13 48.1 0.0 2.6e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal Glyco_transf_25 PF01755.17 CAM43852.1 - 0.021 14.7 0.1 0.058 13.2 0.0 1.7 2 0 0 2 2 2 0 Glycosyltransferase family 25 (LPS biosynthesis protein) eIF-6 PF01912.18 CAM43853.1 - 3.2e-79 264.9 0.6 4.7e-79 264.4 0.4 1.3 2 0 0 2 2 2 1 eIF-6 family Pkinase PF00069.25 CAM43854.1 - 6.6e-74 248.6 0.0 9.9e-74 248.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM43854.1 - 3.2e-39 134.8 0.0 4.8e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM43854.1 - 1.1e-05 25.0 0.0 1.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CAM43854.1 - 0.0008 18.8 0.3 0.0018 17.6 0.2 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 CAM43854.1 - 0.0077 15.8 0.1 0.015 14.9 0.1 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.23 CAM43854.1 - 0.008 16.1 0.1 0.38 10.6 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 CAM43855.1 - 1.9e-52 178.3 0.0 3.1e-52 177.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM43855.1 - 2.9e-32 112.0 0.0 4.7e-32 111.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CAM43855.1 - 0.0038 17.2 0.0 0.0089 16.0 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family ETRAMP PF09716.10 CAM43855.1 - 0.027 14.5 0.0 0.073 13.1 0.0 1.7 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Ribosomal_S13 PF00416.22 CAM43857.1 - 4.5e-42 143.5 0.3 5.2e-42 143.3 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DUF2746 PF10874.8 CAM43857.1 - 0.13 12.7 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) Ribosomal_S13 PF00416.22 CAM43858.1 - 4.5e-42 143.5 0.3 5.2e-42 143.3 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DUF2746 PF10874.8 CAM43858.1 - 0.13 12.7 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) AAA_6 PF12774.7 CAM43859.2 - 1.6e-152 507.2 0.0 1.2e-151 504.3 0.0 2.3 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CAM43859.2 - 1.8e-111 373.1 11.8 1.8e-111 373.1 11.8 3.4 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 CAM43859.2 - 4.4e-100 334.9 14.0 1.2e-99 333.4 0.0 5.1 5 0 0 5 5 4 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 CAM43859.2 - 1.6e-98 329.2 0.8 2.5e-97 325.2 0.0 2.8 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CAM43859.2 - 4.1e-77 258.2 0.0 4.1e-77 258.2 0.0 4.3 5 0 0 5 5 5 1 ATP-binding dynein motor region AAA_7 PF12775.7 CAM43859.2 - 3e-64 215.9 3.2 1.3e-62 210.5 0.0 3.1 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CAM43859.2 - 4.7e-53 179.4 0.0 2.9e-52 176.8 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CAM43859.2 - 1.4e-48 163.9 0.0 3.1e-46 156.3 0.0 4.3 4 0 0 4 4 3 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 CAM43859.2 - 7.4e-46 156.7 7.6 7.4e-46 156.7 7.6 2.0 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 CAM43859.2 - 2.1e-23 82.8 0.5 1.1e-22 80.5 0.1 2.5 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CAM43859.2 - 4.4e-16 59.1 0.1 0.00024 21.1 0.0 7.6 7 2 0 7 7 6 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 CAM43859.2 - 2e-14 53.6 0.0 7.5e-14 51.8 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 CAM43859.2 - 8e-10 39.1 0.3 1e-05 25.9 0.0 4.3 5 0 0 5 5 3 2 AAA domain AAA PF00004.29 CAM43859.2 - 5.3e-06 26.9 0.0 0.18 12.2 0.0 3.4 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CAM43859.2 - 2.6e-05 24.6 0.0 0.34 11.3 0.0 4.0 4 0 0 4 4 4 2 RNA helicase ATG16 PF08614.11 CAM43859.2 - 5.2e-05 23.6 6.1 5.2e-05 23.6 6.1 4.1 4 0 0 4 4 3 1 Autophagy protein 16 (ATG16) NACHT PF05729.12 CAM43859.2 - 0.00053 19.9 1.1 0.014 15.4 0.0 3.4 3 0 0 3 3 2 1 NACHT domain AAA_30 PF13604.6 CAM43859.2 - 0.0023 17.7 0.0 2.6 7.7 0.1 3.2 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 CAM43859.2 - 0.004 17.5 7.8 1.9 8.8 0.0 5.0 6 0 0 6 6 4 2 AAA ATPase domain AAA_33 PF13671.6 CAM43859.2 - 0.01 16.0 0.2 1.4 9.1 0.0 3.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CAM43859.2 - 0.012 16.1 0.1 3.4 8.2 0.0 4.1 4 0 0 4 4 2 0 AAA domain AAA_24 PF13479.6 CAM43859.2 - 0.013 15.2 0.0 4.8 6.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.15 CAM43859.2 - 0.087 12.7 0.2 17 5.3 0.1 3.0 2 0 0 2 2 2 0 Rad17 P-loop domain Med29 PF11568.8 CAM43860.1 - 0.13 12.5 0.0 0.52 10.5 0.0 1.9 2 0 0 2 2 2 0 Mediator complex subunit 29 DUF148 PF02520.17 CAM43861.1 - 0.048 13.8 0.7 0.079 13.1 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF148 S10_plectin PF03501.15 CAM43862.1 - 9.5e-36 121.8 0.0 1.1e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain API5 PF05918.11 CAM43862.1 - 1.8 7.3 8.2 2.7 6.7 8.2 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) S10_plectin PF03501.15 CAM43863.1 - 9.5e-36 121.8 0.0 1.1e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain API5 PF05918.11 CAM43863.1 - 1.8 7.3 8.2 2.7 6.7 8.2 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) WD40 PF00400.32 CAM43864.1 - 2.7e-09 37.5 17.9 1.2e-07 32.3 0.4 6.9 7 1 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM43864.1 - 1.3e-07 31.8 0.0 1.2 9.5 0.0 5.0 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 CAM43864.1 - 0.00029 20.0 0.1 0.07 12.2 0.1 4.1 4 1 0 5 5 5 1 Coatomer WD associated region Clathrin PF00637.20 CAM43864.1 - 0.00034 20.5 1.0 1.3 8.9 0.0 3.8 2 1 2 4 4 4 2 Region in Clathrin and VPS SNAP PF14938.6 CAM43864.1 - 0.0033 16.9 0.2 0.0033 16.9 0.2 2.3 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 CAM43864.1 - 0.0033 17.3 1.6 0.61 10.2 0.0 4.2 5 1 0 5 5 5 1 Tetratricopeptide repeat Nic96 PF04097.14 CAM43864.1 - 0.0047 15.4 0.0 0.0093 14.5 0.0 1.4 1 0 0 1 1 1 1 Nup93/Nic96 DUF2802 PF10975.8 CAM43864.1 - 0.0048 17.0 0.1 0.035 14.2 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2802) TPR_14 PF13428.6 CAM43864.1 - 0.0051 17.5 7.6 5.1 8.2 0.0 5.6 4 2 2 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CAM43864.1 - 0.0069 16.6 1.8 0.48 10.7 0.0 3.6 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 CAM43864.1 - 0.14 12.4 3.5 39 4.6 0.0 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat PPR PF01535.20 CAM43864.1 - 0.2 11.9 1.7 25 5.4 0.0 4.4 4 0 0 4 4 4 0 PPR repeat TPR_2 PF07719.17 CAM43864.1 - 0.72 10.1 11.3 17 5.8 0.2 5.7 7 0 0 7 7 5 0 Tetratricopeptide repeat zf-RING_6 PF14835.6 CAM43864.1 - 1.5 8.8 9.6 0.085 12.7 1.1 2.7 2 0 0 2 2 2 0 zf-RING of BARD1-type protein TPR_1 PF00515.28 CAM43864.1 - 4 7.4 8.3 45 4.1 0.4 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat LOH1CR12 PF10158.9 CAM43865.1 - 0.53 10.3 3.7 0.66 10.0 0.8 2.5 3 0 0 3 3 3 0 Tumour suppressor protein HSM3_C PF18794.1 CAM43867.1 - 0.12 12.0 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 DNA mismatch repair protein HSM3, C terminal domain CLAMP PF14769.6 CAM43869.1 - 1.1e-29 102.7 1.4 3e-29 101.4 1.2 1.8 1 1 1 2 2 2 1 Flagellar C1a complex subunit C1a-32 DUF3801 PF12687.7 CAM43869.1 - 0.054 13.6 0.0 0.058 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) MerR-DNA-bind PF09278.11 CAM43869.1 - 0.93 10.1 4.4 0.85 10.2 0.3 2.6 2 0 0 2 2 2 0 MerR, DNA binding Vir_act_alpha_C PF10400.9 CAM43869.1 - 5.9 7.7 6.5 7.3 7.3 0.5 3.2 3 1 1 4 4 4 0 Virulence activator alpha C-term Ribonuclease_3 PF00636.26 CAM43870.1 - 0.002 18.7 0.0 0.0066 17.1 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease III domain WSD PF15613.6 CAM43871.1 - 5.6e-08 33.2 0.6 3.5e-07 30.6 0.0 2.8 2 0 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 CAM43871.1 - 0.0056 17.0 0.1 0.017 15.4 0.1 1.9 1 0 0 1 1 1 1 DDT domain Ribosomal_L24e PF01246.20 CAM43872.1 - 4.9e-21 74.7 1.1 4.9e-21 74.7 1.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e SPC12 PF06645.13 CAM43873.1 - 1.8 8.7 6.0 15 5.8 0.8 2.8 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Ribosomal_L24e PF01246.20 CAM43875.1 - 4.9e-21 74.7 1.1 4.9e-21 74.7 1.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e HORMA PF02301.18 CAM43876.1 - 8e-48 162.8 0.0 1.1e-47 162.4 0.0 1.2 1 0 0 1 1 1 1 HORMA domain SPEG_u2 PF16650.5 CAM43877.1 - 4.2 7.6 5.4 19 5.5 0.3 2.5 2 0 0 2 2 2 0 Unstructured region on SPEG complex protein 3HCDH_N PF02737.18 CAM43879.1 - 1.6e-56 191.0 1.9 2.1e-56 190.7 1.9 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 CAM43879.1 - 2.4e-34 117.8 0.1 2.3e-33 114.7 0.0 2.3 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 CAM43879.1 - 0.014 15.5 2.7 0.75 10.0 2.7 2.2 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Oxidored_nitro PF00148.19 CAM43879.1 - 0.1 11.3 0.2 0.84 8.3 0.1 1.9 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase Pyr_redox PF00070.27 CAM43879.1 - 0.18 12.4 0.7 0.42 11.2 0.4 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Rhabdo_ncap PF00945.18 CAM43880.1 - 0.12 11.2 0.0 0.28 10.0 0.0 1.5 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Memo PF01875.17 CAM43881.1 - 8.3e-62 208.8 0.0 1.1e-61 208.4 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein CorA PF01544.18 CAM43882.1 - 4e-05 23.1 0.2 0.00025 20.5 0.2 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Glyco_transf_22 PF03901.17 CAM43885.1 - 8.6e-71 239.3 22.1 1.1e-70 239.0 22.1 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PilX_N PF14341.6 CAM43885.1 - 0.018 15.0 1.8 0.018 15.0 1.8 2.3 2 0 0 2 2 2 0 PilX N-terminal GST_C_6 PF17171.4 CAM43886.1 - 0.011 15.5 0.1 0.084 12.7 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF4890 PF16231.5 CAM43887.1 - 0.025 15.0 1.3 0.05 14.1 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4890) PP2C PF00481.21 CAM43888.1 - 1e-08 35.1 0.0 2.5e-08 33.9 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C Agenet PF05641.12 CAM43888.1 - 0.05 14.1 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 Agenet domain zf-TFIIB PF13453.6 CAM43888.1 - 0.1 11.9 0.1 1.5 8.2 0.0 2.4 2 0 0 2 2 2 0 Transcription factor zinc-finger DUF5393 PF17371.2 CAM43889.1 - 0 1172.0 12.4 0 1171.8 12.4 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5393) S4 PF01479.25 CAM43890.1 - 2.6e-13 49.4 0.3 5.7e-13 48.3 0.3 1.6 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 CAM43890.1 - 1.1e-07 32.6 0.2 2.4e-07 31.6 0.2 1.8 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain TyrRSs_C PF16714.5 CAM43890.1 - 0.019 14.7 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Tyrosyl-tRNA synthetase C-terminal domain Glycolytic PF00274.19 CAM43891.2 - 3e-143 476.8 0.0 3.3e-143 476.6 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I SIP1 PF04938.12 CAM43893.1 - 6.1e-05 22.8 0.0 0.00019 21.3 0.0 2.0 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) BILBO1_N PF18281.1 CAM43894.1 - 2.2e-30 104.9 1.0 4.1e-30 104.1 1.0 1.5 1 0 0 1 1 1 1 BILBO1 N-terminal domain CENP-F_leu_zip PF10473.9 CAM43894.1 - 0.0089 16.0 12.0 0.018 15.1 9.9 2.0 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0242 PF06785.11 CAM43894.1 - 0.013 15.6 0.4 0.017 15.3 0.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TAF4 PF05236.14 CAM43894.1 - 0.82 9.4 11.9 1.3 8.7 11.9 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family ADIP PF11559.8 CAM43894.1 - 2.1 8.4 12.8 14 5.7 11.4 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding GAS PF13851.6 CAM43894.1 - 2.8 7.2 11.2 5.5 6.3 11.2 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 CAM43894.1 - 6.7 7.2 18.3 51 4.4 18.3 2.2 1 1 0 1 1 1 0 Apg6 coiled-coil region SlyX PF04102.12 CAM43895.1 - 0.46 11.1 7.9 0.33 11.6 3.3 2.4 1 1 1 2 2 2 0 SlyX DnaJ PF00226.31 CAM43896.2 - 3.1e-06 27.2 0.1 7.3e-06 26.0 0.1 1.6 1 1 0 1 1 1 1 DnaJ domain NARP1 PF12569.8 CAM43897.1 - 7.6e-85 285.8 11.2 3.1e-80 270.5 6.7 3.0 2 1 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 CAM43897.1 - 7.8e-16 56.8 19.3 3.7e-05 23.5 0.0 8.0 9 0 0 9 9 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 CAM43897.1 - 7.7e-12 44.5 11.7 8.8e-06 25.3 0.0 6.8 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 CAM43897.1 - 9.7e-12 45.2 14.5 0.00066 20.1 0.0 5.2 6 0 0 6 6 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 CAM43897.1 - 4e-10 39.1 5.4 0.079 13.2 0.0 6.2 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 CAM43897.1 - 1e-09 38.4 24.5 0.021 15.6 0.1 8.5 7 2 3 10 10 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 CAM43897.1 - 1.4e-09 37.7 2.2 0.28 11.7 0.1 5.3 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 CAM43897.1 - 3.9e-08 33.3 12.7 0.00018 21.6 0.0 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 CAM43897.1 - 2.3e-06 27.2 2.3 0.042 13.5 0.0 5.8 6 0 0 6 6 6 1 TPR repeat TPR_16 PF13432.6 CAM43897.1 - 4.1e-06 27.3 17.4 0.014 16.0 5.1 6.2 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 CAM43897.1 - 5.2e-06 26.7 17.8 0.12 12.7 0.0 6.2 6 2 1 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 CAM43897.1 - 6.8e-05 22.6 9.0 2 8.6 0.1 6.6 7 0 0 7 7 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CAM43897.1 - 0.00097 19.3 15.7 0.17 12.1 0.0 5.6 4 2 3 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CAM43897.1 - 0.001 18.9 2.7 3.4 7.7 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CAM43897.1 - 0.0012 18.8 0.5 9.2 6.4 0.0 4.6 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat DUF1771 PF08590.10 CAM43897.1 - 6.6 7.2 15.2 0.58 10.6 3.9 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF1771) zf-PARP PF00645.18 CAM43898.1 - 5.2e-20 72.1 2.2 1.4e-19 70.7 2.2 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-CCHH PF10283.9 CAM43898.1 - 8e-09 35.3 4.3 1.5e-08 34.5 4.3 1.3 1 0 0 1 1 1 1 PBZ domain Trypsin_2 PF13365.6 CAM43899.1 - 2.3e-05 25.4 0.1 3.4e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain ADK PF00406.22 CAM43900.1 - 1.9e-41 141.7 0.0 3.5e-41 140.8 0.0 1.4 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CAM43900.1 - 1.5e-25 90.2 0.0 1.8e-24 86.7 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CAM43900.1 - 8.5e-11 42.5 0.1 3.5e-10 40.5 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CAM43900.1 - 0.00044 20.4 0.5 0.0013 18.9 0.0 2.2 2 2 0 2 2 2 1 AAA domain Hydin_ADK PF17213.3 CAM43900.1 - 0.0011 19.3 0.2 0.017 15.4 0.0 2.4 1 1 1 2 2 2 1 Hydin Adenylate kinase-like domain Zeta_toxin PF06414.12 CAM43900.1 - 0.02 14.2 0.3 0.077 12.3 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin Thymidylate_kin PF02223.17 CAM43900.1 - 0.026 14.2 0.0 11 5.6 0.0 2.8 3 0 0 3 3 3 0 Thymidylate kinase dNK PF01712.19 CAM43900.1 - 0.031 14.1 0.4 13 5.5 0.0 3.0 3 0 0 3 3 3 0 Deoxynucleoside kinase AAA PF00004.29 CAM43901.1 - 5.1e-95 314.9 0.0 4.5e-46 156.5 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAM43901.1 - 7.6e-27 92.9 8.1 2.1e-13 49.8 0.3 3.1 3 1 0 3 3 2 2 AAA+ lid domain CDC48_N PF02359.18 CAM43901.1 - 1e-19 70.5 0.3 4.4e-19 68.5 0.1 2.3 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 CAM43901.1 - 6.8e-14 51.9 0.0 9.1e-06 25.5 0.0 3.0 2 2 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CAM43901.1 - 1.9e-12 47.9 0.2 0.00046 20.6 0.0 4.0 2 2 1 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 CAM43901.1 - 6.2e-12 46.0 0.0 3.2e-06 27.4 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CAM43901.1 - 1.7e-11 44.4 0.0 5.5e-06 26.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 CAM43901.1 - 1.9e-10 40.9 0.2 5.2e-05 23.3 0.1 3.4 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) CDC48_2 PF02933.17 CAM43901.1 - 5e-10 39.0 0.0 1.2e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 CAM43901.1 - 2e-09 37.8 0.5 0.039 14.2 0.0 4.0 2 2 2 4 4 4 2 AAA domain TIP49 PF06068.13 CAM43901.1 - 9.6e-09 34.9 0.0 0.00039 19.7 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_18 PF13238.6 CAM43901.1 - 1.6e-07 31.9 0.0 0.016 15.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 CAM43901.1 - 2.2e-07 31.0 0.0 0.0061 16.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CAM43901.1 - 2.3e-07 31.1 0.0 0.0057 17.0 0.0 3.0 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 CAM43901.1 - 4.4e-07 29.5 0.2 0.031 13.7 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CAM43901.1 - 4.4e-06 26.6 0.0 0.075 12.8 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein ABC_tran PF00005.27 CAM43901.1 - 1.4e-05 25.7 0.0 0.055 14.0 0.0 3.1 2 1 0 2 2 2 1 ABC transporter Vps4_C PF09336.10 CAM43901.1 - 1.5e-05 24.9 0.1 0.0011 18.9 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Zeta_toxin PF06414.12 CAM43901.1 - 1.9e-05 24.1 0.0 0.11 11.8 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_28 PF13521.6 CAM43901.1 - 2.2e-05 24.8 0.0 0.24 11.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.6 CAM43901.1 - 2.5e-05 24.7 0.0 0.18 12.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 CAM43901.1 - 3.2e-05 24.0 0.1 0.43 10.4 0.0 2.9 2 1 0 2 2 2 2 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 CAM43901.1 - 3.6e-05 23.0 0.0 0.056 12.5 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 CAM43901.1 - 4e-05 23.3 1.7 1.4 8.5 0.1 3.6 2 2 1 3 3 3 1 AAA domain NACHT PF05729.12 CAM43901.1 - 5.8e-05 23.1 0.1 0.17 11.8 0.0 3.1 3 0 0 3 3 3 1 NACHT domain AAA_24 PF13479.6 CAM43901.1 - 7.6e-05 22.5 0.0 0.13 12.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 CAM43901.1 - 8.5e-05 22.0 1.7 1.5 8.1 0.0 3.6 2 1 1 3 3 3 1 KaiC Sigma54_activat PF00158.26 CAM43901.1 - 0.0001 22.1 0.1 0.7 9.6 0.1 3.2 2 1 0 2 2 2 2 Sigma-54 interaction domain TsaE PF02367.17 CAM43901.1 - 0.00011 22.2 0.0 0.64 10.0 0.0 2.7 3 0 0 3 3 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bac_DnaA PF00308.18 CAM43901.1 - 0.00015 21.7 0.0 0.19 11.6 0.0 2.4 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_7 PF12775.7 CAM43901.1 - 0.00019 21.0 0.0 0.49 9.9 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region Viral_helicase1 PF01443.18 CAM43901.1 - 0.00022 21.0 0.0 0.015 15.1 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 CAM43901.1 - 0.00041 20.3 1.1 10 6.0 0.0 4.2 3 1 1 4 4 4 0 NTPase AAA_3 PF07726.11 CAM43901.1 - 0.00047 20.0 0.0 1.4 8.8 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 CAM43901.1 - 0.00071 18.8 0.0 0.98 8.6 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain ResIII PF04851.15 CAM43901.1 - 0.001 19.1 0.0 0.092 12.7 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.6 CAM43901.1 - 0.0016 18.6 0.0 0.66 10.1 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain PhoH PF02562.16 CAM43901.1 - 0.0025 17.3 0.1 1.4 8.3 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein DUF2075 PF09848.9 CAM43901.1 - 0.0031 16.8 0.0 0.94 8.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Rad17 PF03215.15 CAM43901.1 - 0.0076 16.2 0.0 2.1 8.2 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain DUF815 PF05673.13 CAM43901.1 - 0.012 14.8 0.0 5.1 6.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Molydop_binding PF01568.21 CAM43901.1 - 0.02 14.9 0.0 0.045 13.8 0.0 1.6 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain AAA_19 PF13245.6 CAM43901.1 - 0.025 14.9 1.8 7.4 6.9 0.1 3.4 3 1 1 4 4 2 0 AAA domain Cytidylate_kin2 PF13189.6 CAM43901.1 - 0.032 14.4 1.0 1.7 8.7 0.0 2.8 4 0 0 4 4 2 0 Cytidylate kinase-like family Cytidylate_kin PF02224.18 CAM43901.1 - 0.034 13.9 0.0 5.5 6.7 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase AAA_11 PF13086.6 CAM43901.1 - 0.041 13.7 0.0 12 5.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CAM43901.1 - 0.046 13.5 0.0 7.3 6.4 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain DEAD PF00270.29 CAM43901.1 - 0.047 13.5 0.2 5.4 6.7 0.0 3.4 4 0 0 4 4 4 0 DEAD/DEAH box helicase SKI PF01202.22 CAM43901.1 - 0.057 13.5 0.1 18 5.5 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase AAA_23 PF13476.6 CAM43901.1 - 0.066 13.7 0.2 24 5.4 0.0 2.8 2 1 0 2 2 2 0 AAA domain TEX19 PF15553.6 CAM43901.1 - 0.069 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Testis-expressed protein 19 AAA_30 PF13604.6 CAM43901.1 - 0.079 12.7 0.1 9.5 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain CPT PF07931.12 CAM43901.1 - 0.12 12.2 0.0 3.9 7.3 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Zot PF05707.12 CAM43901.1 - 0.14 11.8 0.0 1.8 8.1 0.0 2.6 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) KAP_NTPase PF07693.14 CAM43901.1 - 0.15 11.3 0.1 6 6.0 0.0 3.0 2 2 1 4 4 4 0 KAP family P-loop domain AFG1_ATPase PF03969.16 CAM43901.1 - 0.17 10.8 1.6 11 4.8 0.0 2.9 3 0 0 3 3 3 0 AFG1-like ATPase Aa_trans PF01490.18 CAM43902.1 - 3.5e-41 141.3 23.7 4.3e-41 141.0 23.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trypsin_2 PF13365.6 CAM43903.1 - 2.6e-05 25.2 0.1 3.9e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Hrs_helical PF12210.8 CAM43904.2 - 0.1 13.1 6.0 0.078 13.5 1.2 2.4 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF4407 PF14362.6 CAM43904.2 - 0.17 11.2 4.3 0.35 10.2 4.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SlyX PF04102.12 CAM43904.2 - 5.2 7.8 12.0 1.3 9.7 1.1 3.6 3 1 1 4 4 4 0 SlyX ARL2_Bind_BART PF11527.8 CAM43906.1 - 9.9e-31 106.2 0.1 9.9e-31 106.2 0.1 1.9 2 0 0 2 2 2 1 The ARF-like 2 binding protein BART UIM PF02809.20 CAM43906.1 - 0.011 15.6 0.4 0.011 15.6 0.4 3.1 3 0 0 3 3 3 0 Ubiquitin interaction motif COMPASS-Shg1 PF05205.12 CAM43906.1 - 3 8.6 6.7 81 4.0 2.8 3.2 3 0 0 3 3 3 0 COMPASS (Complex proteins associated with Set1p) component shg1 zf-RanBP PF00641.18 CAM43907.2 - 0.0058 15.9 4.8 0.0058 15.9 4.8 15.6 13 2 1 14 14 14 5 Zn-finger in Ran binding protein and others DZR PF12773.7 CAM43907.2 - 0.16 12.0 144.6 0.025 14.6 12.4 10.5 8 2 2 10 10 10 0 Double zinc ribbon HTH_31 PF13560.6 CAM43907.2 - 4.5 7.7 8.3 5.8 7.4 1.9 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain zf-RanBP PF00641.18 CAM43908.2 - 7.1e-21 73.2 86.2 7.4e-08 31.6 2.9 10.1 9 1 1 10 10 10 8 Zn-finger in Ran binding protein and others DZR PF12773.7 CAM43908.2 - 2.4e-06 27.4 65.0 0.011 15.8 7.0 6.7 4 3 2 6 6 6 6 Double zinc ribbon Vps36-NZF-N PF16988.5 CAM43908.2 - 0.21 11.0 0.1 0.21 11.0 0.1 7.6 8 2 2 10 10 10 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain EF1_GNE PF00736.19 CAM43909.1 - 3e-26 91.4 1.0 4.7e-26 90.8 1.0 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain UBA2_C PF16195.5 CAM43909.1 - 0.031 15.0 4.1 0.063 14.0 4.1 1.5 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus DUF778 PF05608.12 CAM43909.1 - 0.085 13.2 0.0 0.09 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF778) GST_C_6 PF17171.4 CAM43909.1 - 0.11 12.3 0.0 0.42 10.5 0.0 2.0 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Chorein_N PF12624.7 CAM43910.2 - 7.1e-24 84.2 0.2 9.3e-11 41.9 0.0 2.8 2 0 0 2 2 2 2 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 CAM43910.2 - 1.4e-11 44.5 0.0 1.9e-07 31.0 0.0 2.4 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 CAM43910.2 - 0.00017 21.5 0.6 0.002 18.0 0.6 2.5 1 1 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal DUF5582 PF17819.1 CAM43911.1 - 0.002 18.6 0.4 0.0036 17.8 0.4 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5582) DUF4400 PF14348.6 CAM43911.1 - 0.096 12.2 0.1 0.12 11.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) EF-hand_7 PF13499.6 CAM43911.1 - 0.15 12.5 0.0 0.35 11.4 0.0 1.7 1 1 0 1 1 1 0 EF-hand domain pair Kelch_4 PF13418.6 CAM43913.1 - 7.6e-15 54.7 0.2 5.1e-06 26.4 0.0 5.1 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 CAM43913.1 - 3.5e-10 39.3 0.1 5.7e-05 22.6 0.0 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 CAM43913.1 - 6.3e-09 35.6 0.2 0.002 18.0 0.0 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 CAM43913.1 - 2.6e-08 33.9 0.4 0.038 14.3 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 CAM43913.1 - 1.4e-07 31.2 0.1 0.024 14.6 0.0 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 CAM43913.1 - 2.3e-07 30.9 4.8 0.0031 17.7 0.0 5.2 6 0 0 6 6 6 2 Galactose oxidase, central domain DUF4719 PF15843.5 CAM43914.1 - 0.12 12.5 2.0 0.43 10.7 1.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4719) DUF4090 PF13319.6 CAM43916.1 - 0.16 12.2 0.0 0.42 10.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4090) Med30 PF11315.8 CAM43917.1 - 0.035 14.3 0.6 0.087 13.0 0.4 1.7 1 1 1 2 2 2 0 Mediator complex subunit 30 P4Ha_N PF08336.11 CAM43917.1 - 0.048 13.7 0.3 0.065 13.3 0.3 1.3 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region AAA_23 PF13476.6 CAM43917.1 - 0.049 14.1 0.4 0.056 13.9 0.4 1.1 1 0 0 1 1 1 0 AAA domain Complex1_LYR_2 PF13233.6 CAM43917.1 - 0.062 14.1 0.2 0.25 12.1 0.1 1.9 1 1 0 1 1 1 0 Complex1_LYR-like DUF1451 PF07295.11 CAM43917.1 - 0.25 11.3 4.4 0.37 10.8 4.4 1.3 1 0 0 1 1 1 0 Zinc-ribbon containing domain Laminin_II PF06009.12 CAM43917.1 - 0.36 10.9 4.8 0.78 9.7 0.4 2.1 2 0 0 2 2 2 0 Laminin Domain II Syntaxin-6_N PF09177.11 CAM43917.1 - 1.7 9.3 6.3 4.2 8.0 1.5 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Rho_Binding PF08912.11 CAM43917.1 - 1.8 9.4 5.3 1.5 9.7 1.7 2.1 2 0 0 2 2 2 0 Rho Binding Pkinase PF00069.25 CAM43918.1 - 1.4e-56 191.8 0.0 2e-56 191.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM43918.1 - 2.3e-35 122.1 0.0 3.6e-35 121.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM43918.1 - 7.1e-06 25.5 0.0 1.9e-05 24.1 0.0 1.6 1 1 1 2 2 2 1 Kinase-like PH PF00169.29 CAM43918.1 - 0.0002 21.8 0.3 0.00074 20.0 0.3 1.9 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 CAM43918.1 - 0.00068 20.0 0.0 0.0015 18.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 CAM43918.1 - 0.044 14.1 0.1 0.15 12.5 0.1 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain PH_4 PF15404.6 CAM43918.1 - 0.056 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Pkinase_fungal PF17667.1 CAM43918.1 - 0.14 10.9 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 CAM43919.1 - 6.6e-53 179.7 0.0 9.7e-53 179.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM43919.1 - 2.2e-35 122.2 0.0 4.5e-35 121.2 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase PH PF00169.29 CAM43919.1 - 4.4e-07 30.4 0.0 1.2e-06 29.0 0.0 1.7 1 1 0 1 1 1 1 PH domain Kinase-like PF14531.6 CAM43919.1 - 9.2e-07 28.4 0.0 1.7e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH_9 PF15410.6 CAM43919.1 - 0.03 14.7 0.0 0.077 13.4 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.6 CAM43919.1 - 0.071 13.5 0.1 0.56 10.6 0.1 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain ELMO_CED12 PF04727.13 CAM43920.1 - 1.3e-33 116.6 0.0 1.9e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family zf-B_box PF00643.24 CAM43921.1 - 1e-07 31.9 25.1 2e-07 31.1 7.5 3.7 5 0 0 5 5 5 2 B-box zinc finger Baculo_PEP_C PF04513.12 CAM43921.1 - 2.7e-05 24.2 0.0 4.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 CAM43921.1 - 0.024 14.5 2.5 0.042 13.7 2.5 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Spectrin PF00435.21 CAM43921.1 - 0.16 12.5 0.8 0.37 11.3 0.8 1.6 1 0 0 1 1 1 0 Spectrin repeat DUF4407 PF14362.6 CAM43923.1 - 0.0084 15.5 22.6 0.011 15.1 13.8 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4407) Pneumo_att_G PF05539.11 CAM43923.1 - 0.033 13.8 0.7 0.065 12.8 0.7 1.4 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DUF5340 PF17275.2 CAM43923.1 - 0.9 9.7 4.9 1.2 9.3 2.9 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5340) STAG PF08514.11 CAM43925.1 - 1.7e-21 76.3 0.3 6.6e-21 74.4 0.3 2.1 1 0 0 1 1 1 1 STAG domain Fe_dep_repr_C PF02742.15 CAM43925.1 - 0.1 12.7 0.1 0.29 11.2 0.1 1.8 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain IFT43 PF15305.6 CAM43926.1 - 0.057 13.6 1.6 0.086 13.0 0.9 1.6 2 0 0 2 2 2 0 Intraflagellar transport protein 43 Proteasome PF00227.26 CAM43927.1 - 4.5e-56 189.4 0.1 5.6e-56 189.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CAM43927.1 - 2.5e-13 49.4 0.0 6.5e-13 48.1 0.0 1.8 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature zf-CCHC PF00098.23 CAM43928.1 - 3.5e-42 140.7 39.3 8e-10 38.3 3.1 5.1 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_3 PF13917.6 CAM43928.1 - 3.5e-13 49.3 27.3 0.0097 15.9 0.9 5.0 1 1 4 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.6 CAM43928.1 - 4.6e-08 32.7 28.5 0.092 12.5 1.0 5.0 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_6 PF15288.6 CAM43928.1 - 3.9e-05 23.4 29.8 0.067 13.0 0.9 5.1 2 2 3 5 5 5 4 Zinc knuckle zf-CCHC_2 PF13696.6 CAM43928.1 - 0.00014 21.6 29.1 0.37 10.7 2.1 5.3 5 0 0 5 5 5 4 Zinc knuckle HscB_4_cys PF18256.1 CAM43928.1 - 0.068 13.0 25.4 9.5 6.1 1.1 5.5 5 0 0 5 5 5 0 Co-chaperone HscB tetracysteine metal binding motif zf-CCHC_5 PF14787.6 CAM43928.1 - 0.097 12.4 30.3 1.6 8.5 0.5 5.1 5 0 0 5 5 5 0 GAG-polyprotein viral zinc-finger TRAF6_Z2 PF18048.1 CAM43928.1 - 0.14 12.2 12.6 19 5.4 0.1 5.3 5 0 0 5 5 5 0 TNF receptor-associated factor 6 zinc finger 2 zf-CCHC PF00098.23 CAM43929.1 - 3.1e-42 140.8 40.7 8e-10 38.3 3.1 5.1 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_3 PF13917.6 CAM43929.1 - 2.3e-13 49.9 27.6 0.0097 15.9 0.9 5.0 1 1 4 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.6 CAM43929.1 - 3.1e-08 33.2 28.8 0.092 12.5 1.0 5.0 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_6 PF15288.6 CAM43929.1 - 1.6e-05 24.6 31.1 0.019 14.8 1.7 5.1 2 2 3 5 5 5 3 Zinc knuckle zf-CCHC_2 PF13696.6 CAM43929.1 - 0.0032 17.3 29.3 1.2 9.1 1.0 5.3 5 0 0 5 5 5 4 Zinc knuckle TRAF6_Z2 PF18048.1 CAM43929.1 - 0.035 14.2 13.2 19 5.5 0.1 5.3 5 0 0 5 5 5 0 TNF receptor-associated factor 6 zinc finger 2 HscB_4_cys PF18256.1 CAM43929.1 - 0.07 13.0 25.8 8.5 6.3 1.4 5.5 5 0 0 5 5 5 0 Co-chaperone HscB tetracysteine metal binding motif zf-CCHC_5 PF14787.6 CAM43929.1 - 0.071 12.8 30.1 1.6 8.5 0.5 5.1 5 0 0 5 5 5 0 GAG-polyprotein viral zinc-finger Ntox16 PF15523.6 CAM43929.1 - 4.2 7.7 20.7 1.8 8.8 0.2 4.5 1 1 3 4 4 4 0 Novel toxin 16 Clathrin PF00637.20 CAM43930.1 - 3.2e-158 519.9 40.7 6e-27 94.3 2.1 8.3 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 CAM43930.1 - 3.6e-18 65.2 0.3 3.2e-17 62.2 0.0 2.9 3 0 0 3 3 3 1 Clathrin-H-link Clathrin-link PF09268.10 CAM43930.1 - 2.8e-10 39.3 0.3 7.8e-10 37.9 0.3 1.8 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Clathrin_propel PF01394.20 CAM43930.1 - 2.3e-08 34.0 0.1 1.3 9.4 0.0 5.2 5 0 0 5 5 5 3 Clathrin propeller repeat ACDC PF14733.6 CAM43930.1 - 0.003 17.8 0.4 8.6 6.8 0.0 4.2 3 0 0 3 3 3 1 AP2-coincident C-terminal TPR_1 PF00515.28 CAM43930.1 - 0.028 14.2 3.1 21 5.1 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 CAM43930.1 - 0.03 14.4 1.3 51 4.2 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat PDDEXK_10 PF07788.11 CAM43930.1 - 0.098 12.6 3.7 1.4 8.9 0.1 3.6 3 0 0 3 3 3 0 PD-(D/E)XK nuclease superfamily Mic1 PF07035.12 CAM43930.1 - 0.37 10.5 7.2 0.41 10.3 0.0 4.5 6 0 0 6 6 6 0 Colon cancer-associated protein Mic1-like Egg_lysin PF01303.17 CAM43930.1 - 0.53 10.5 3.3 6.9 6.9 0.3 3.2 3 0 0 3 3 3 0 Egg lysin (Sperm-lysin) zf-CCHC PF00098.23 CAM43931.1 - 5.5e-36 121.0 50.5 2.4e-07 30.5 1.9 6.1 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_2 PF13696.6 CAM43931.1 - 1.5e-07 31.1 47.7 4.4e-05 23.2 2.4 6.2 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_3 PF13917.6 CAM43931.1 - 2.1e-07 30.8 37.4 0.021 14.8 3.0 5.5 1 1 4 5 5 5 4 Zinc knuckle zf-CCHC_4 PF14392.6 CAM43931.1 - 1e-06 28.4 35.4 0.12 12.1 1.6 6.0 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_5 PF14787.6 CAM43931.1 - 7.4e-05 22.4 39.1 0.016 14.9 0.4 5.9 4 2 2 6 6 6 5 GAG-polyprotein viral zinc-finger DUF5582 PF17819.1 CAM43932.1 - 0.002 18.6 0.4 0.0036 17.8 0.4 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5582) DUF4400 PF14348.6 CAM43932.1 - 0.096 12.2 0.1 0.12 11.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) EF-hand_7 PF13499.6 CAM43932.1 - 0.15 12.5 0.0 0.35 11.4 0.0 1.7 1 1 0 1 1 1 0 EF-hand domain pair DUF4719 PF15843.5 CAM43934.1 - 0.11 12.7 2.1 0.22 11.6 0.3 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4719) zf-CCHC PF00098.23 CAM43935.1 - 6.8e-75 244.0 89.4 9.5e-09 34.9 3.1 9.2 9 0 0 9 9 9 9 Zinc knuckle zf-CCHC_3 PF13917.6 CAM43935.1 - 1.4e-28 98.6 52.5 0.00067 19.6 0.4 9.1 4 2 5 9 9 9 9 Zinc knuckle zf-CCHC_2 PF13696.6 CAM43935.1 - 3.8e-11 42.6 67.7 0.00036 20.3 1.9 9.5 9 0 0 9 9 9 6 Zinc knuckle zf-CCHC_5 PF14787.6 CAM43935.1 - 9.5e-09 34.8 63.4 0.52 10.1 1.3 9.2 9 0 0 9 9 9 9 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 CAM43935.1 - 5.9e-07 29.1 53.4 2.3 8.0 0.3 9.1 9 0 0 9 9 9 9 Zinc knuckle Neil1-DNA_bind PF09292.10 CAM43935.1 - 0.028 14.4 4.0 65 3.6 0.1 5.6 6 0 0 6 6 6 0 Endonuclease VIII-like 1, DNA bind TRAF6_Z2 PF18048.1 CAM43935.1 - 0.042 13.9 32.5 44 4.3 0.1 8.9 9 0 0 9 9 9 0 TNF receptor-associated factor 6 zinc finger 2 Gla PF00594.20 CAM43935.1 - 0.047 13.9 4.8 47 4.3 0.0 4.9 5 0 0 5 5 5 0 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain zf-CCHC_6 PF15288.6 CAM43935.1 - 0.29 11.0 73.7 2 8.3 2.0 9.2 8 1 1 9 9 9 0 Zinc knuckle Ntox16 PF15523.6 CAM43935.1 - 0.51 10.6 47.0 1.9 8.8 3.3 8.0 7 1 0 8 8 8 0 Novel toxin 16 Proteasome PF00227.26 CAM43936.1 - 1.5e-48 164.8 0.2 1.8e-48 164.5 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit S4 PF01479.25 CAM43937.1 - 3.7e-07 29.7 0.1 5.3e-06 26.1 0.0 2.5 2 0 0 2 2 2 1 S4 domain PseudoU_synth_2 PF00849.22 CAM43937.1 - 2.9e-05 24.2 0.0 5.3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase Q_salvage PF10343.9 CAM43938.1 - 1.8e-17 63.8 0.0 1.5e-15 57.6 0.0 2.5 3 0 0 3 3 3 2 Potential Queuosine, Q, salvage protein family Ank PF00023.30 CAM43938.1 - 0.04 14.4 0.1 0.25 11.9 0.0 2.5 3 0 0 3 3 3 0 Ankyrin repeat Peptidase_M76 PF09768.9 CAM43940.1 - 1.3e-58 197.5 0.2 9.7e-58 194.7 0.2 2.0 1 1 0 1 1 1 1 Peptidase M76 family Dmrt1 PF12374.8 CAM43940.1 - 1.5 9.3 5.1 0.26 11.7 1.0 1.8 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 GPI2 PF06432.11 CAM43942.1 - 1.1e-67 228.5 14.0 1.3e-67 228.2 14.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Beach PF02138.18 CAM43943.2 - 1.9e-106 355.5 0.0 2.7e-106 355.0 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 CAM43943.2 - 1.1e-20 73.6 0.0 2.2e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 CAM43943.2 - 1.1e-05 25.7 0.0 3e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Sec34 PF04136.15 CAM43944.1 - 1.9e-12 47.3 1.2 1.9e-12 47.3 1.2 2.5 3 0 0 3 3 3 1 Sec34-like family DUF5329 PF17263.2 CAM43944.1 - 0.022 14.9 0.5 0.091 13.0 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5329) Lactonase PF10282.9 CAM43946.1 - 0.013 14.8 0.1 0.039 13.2 0.0 1.8 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Aldedh PF00171.22 CAM43947.2 - 2e-166 554.1 0.1 2.2e-166 553.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3253 PF11625.8 CAM43947.2 - 0.043 14.0 0.4 0.13 12.5 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3253) UxaC PF02614.14 CAM43947.2 - 0.3 9.9 0.0 0.42 9.4 0.0 1.1 1 0 0 1 1 1 0 Glucuronate isomerase TPR_1 PF00515.28 CAM43949.2 - 9.2e-16 56.9 4.5 0.0021 17.8 0.0 8.7 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 CAM43949.2 - 3e-14 51.9 11.9 0.026 14.6 0.0 9.6 9 1 1 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 CAM43949.2 - 7.4e-10 39.3 9.3 0.00016 22.3 0.1 5.9 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 CAM43949.2 - 8.4e-10 38.7 9.6 0.00017 21.7 0.1 5.3 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CAM43949.2 - 4.9e-09 36.6 15.7 0.038 14.5 0.1 6.9 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 CAM43949.2 - 9.5e-09 34.8 0.6 0.0019 17.9 0.0 5.1 4 1 1 5 5 5 2 TPR repeat TPR_8 PF13181.6 CAM43949.2 - 5.3e-08 32.5 1.8 2.3 8.7 0.0 7.3 8 1 2 10 10 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 CAM43949.2 - 6.2e-07 29.4 1.2 0.52 10.8 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CAM43949.2 - 8.7e-06 25.9 8.9 0.29 11.4 0.0 5.3 5 1 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 CAM43949.2 - 5.8e-05 23.3 11.5 0.12 12.7 0.0 6.6 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 CAM43949.2 - 0.00023 21.7 22.0 0.43 11.5 0.0 8.4 5 4 3 9 9 9 1 Tetratricopeptide repeat TPR_20 PF14561.6 CAM43949.2 - 0.004 17.5 0.0 0.084 13.2 0.0 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 CAM43949.2 - 0.026 13.7 0.8 3.7 6.7 0.0 3.4 3 1 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 CAM43949.2 - 0.035 13.8 0.0 1.5 8.5 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain TPR_7 PF13176.6 CAM43949.2 - 0.13 12.4 14.8 5.6 7.2 0.1 6.5 7 1 1 8 8 8 0 Tetratricopeptide repeat XRN_N PF03159.18 CAM43950.1 - 1.6e-85 286.4 0.0 1.6e-85 286.4 0.0 2.1 2 1 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 CAM43950.1 - 6.4e-62 209.9 4.4 6.4e-62 209.9 4.4 3.5 2 2 0 2 2 2 1 Xrn1 helical domain SpoIISA_toxin PF14171.6 CAM43951.1 - 1.4 8.6 3.1 2.3 7.9 3.1 1.4 1 1 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system MORN PF02493.20 CAM43952.2 - 9.4e-51 166.8 90.0 5.9e-07 29.0 0.4 19.8 22 0 0 22 22 22 14 MORN repeat DUF3048_C PF17479.2 CAM43952.2 - 8.2 6.9 12.2 3 8.3 0.2 4.5 5 2 1 6 6 6 0 Protein of unknown function (DUF3048) C-terminal domain Ras PF00071.22 CAM43953.2 - 7.9e-14 51.6 0.0 1.3e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAM43953.2 - 4.5e-11 43.0 0.0 9.5e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CAM43953.2 - 0.07 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase DEAD PF00270.29 CAM43955.1 - 3e-42 144.4 0.0 5.9e-42 143.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAM43955.1 - 2.3e-23 82.6 0.0 1.7e-22 79.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CAM43955.1 - 7.9e-15 54.8 0.1 1.6e-14 53.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Menin PF05053.13 CAM43955.1 - 3.7 5.8 10.2 5.3 5.3 10.2 1.1 1 0 0 1 1 1 0 Menin DEAD PF00270.29 CAM43956.1 - 7.9e-46 156.0 0.1 5.5e-45 153.3 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAM43956.1 - 4.7e-28 97.7 0.1 5.3e-27 94.4 0.0 2.7 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAM43956.1 - 5.2e-05 23.3 0.0 0.00018 21.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CAM43956.1 - 0.00048 19.4 0.0 0.00086 18.6 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SNF2_N PF00176.23 CAM43956.1 - 0.062 12.0 0.0 0.096 11.4 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain Ribosomal_S5_C PF03719.15 CAM43957.2 - 4e-11 42.2 0.2 6.4e-11 41.6 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 CAM43957.2 - 1.1e-06 28.5 0.0 2.1e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain DUF1918 PF08940.11 CAM43957.2 - 0.13 11.9 0.0 0.61 9.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) MVP_shoulder PF11978.8 CAM43958.1 - 1.3e-44 151.0 0.0 2.1e-44 150.3 0.0 1.4 1 0 0 1 1 1 1 Shoulder domain Vault PF01505.18 CAM43958.1 - 1.5e-28 98.7 0.0 2.9e-12 46.5 0.0 5.2 5 0 0 5 5 5 3 Major Vault Protein repeat domain Vault_2 PF17794.1 CAM43958.1 - 9e-19 67.6 0.1 1.3e-11 44.7 0.1 3.0 2 0 0 2 2 2 2 Major Vault Protein repeat domain Vault_3 PF17795.1 CAM43958.1 - 7.3e-16 58.0 0.0 7.7e-15 54.7 0.0 2.9 2 1 0 2 2 2 1 Major Vault Protein Repeat domain Vault_4 PF17796.1 CAM43958.1 - 2.6e-14 53.0 0.1 8.7e-13 48.2 0.0 3.1 3 0 0 3 3 3 1 Major Vault Protein repeat domain Tfb4 PF03850.14 CAM43958.1 - 0.37 10.2 5.1 0.63 9.5 5.1 1.3 1 0 0 1 1 1 0 Transcription factor Tfb4 CBF PF03914.17 CAM43959.1 - 1.4e-28 100.0 0.2 1.4e-28 100.0 0.2 2.5 2 1 0 2 2 2 1 CBF/Mak21 family NOC3p PF07540.11 CAM43959.1 - 3.1e-06 27.5 0.1 1.1e-05 25.8 0.1 2.0 1 0 0 1 1 1 1 Nucleolar complex-associated protein Pep_deformylase PF01327.21 CAM43959.1 - 0.042 13.5 0.1 0.082 12.5 0.1 1.5 1 0 0 1 1 1 0 Polypeptide deformylase DUF4337 PF14235.6 CAM43959.1 - 0.92 9.6 5.2 2.1 8.4 0.8 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4337) GAS PF13851.6 CAM43963.1 - 3.5e-53 179.9 29.8 3.5e-53 179.9 29.8 3.7 3 1 1 4 4 4 1 Growth-arrest specific micro-tubule binding Filament PF00038.21 CAM43963.1 - 5.8 6.4 68.2 4.8 6.7 19.7 4.7 1 1 1 2 2 2 0 Intermediate filament protein PBECR1 PF18809.1 CAM43963.1 - 7.8 7.2 12.5 0.57 10.9 3.8 3.2 2 2 1 3 3 3 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease1 TRCF PF03461.15 CAM43964.1 - 0.076 13.4 0.0 13 6.3 0.0 2.8 2 0 0 2 2 2 0 TRCF domain Ribosomal_L37ae PF01780.19 CAM43965.1 - 9.2e-37 125.0 4.5 1e-36 124.9 4.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family C1_1 PF00130.22 CAM43965.1 - 0.0022 17.8 2.3 0.0032 17.3 2.3 1.2 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_13 PF17977.1 CAM43965.1 - 0.05 13.7 1.1 0.071 13.2 1.1 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 CAM43965.1 - 0.065 13.2 2.3 0.11 12.5 2.3 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain NOB1_Zn_bind PF08772.11 CAM43965.1 - 0.16 12.2 3.8 0.43 10.8 0.6 2.3 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-C3HC4 PF00097.25 CAM43966.1 - 3.2e-10 39.7 5.8 4.9e-10 39.1 5.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CAM43966.1 - 1.1e-09 38.0 3.8 1.5e-09 37.5 3.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CAM43966.1 - 3.7e-09 36.3 7.9 6.2e-09 35.6 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CAM43966.1 - 3.9e-09 36.2 5.1 6.6e-09 35.5 5.1 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CAM43966.1 - 5.5e-09 36.2 9.0 8.5e-09 35.6 9.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CAM43966.1 - 6e-09 35.8 5.5 7.7e-09 35.4 3.4 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CAM43966.1 - 8.4e-08 32.2 6.8 1.4e-07 31.5 6.8 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CAM43966.1 - 2.6e-06 27.3 5.2 4.3e-06 26.6 5.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 CAM43966.1 - 0.0016 18.7 9.8 0.0047 17.2 9.8 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 CAM43966.1 - 0.0027 17.5 4.3 0.0062 16.4 4.3 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 CAM43966.1 - 0.0033 17.4 1.9 0.0061 16.6 1.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_IE-1 PF05290.11 CAM43966.1 - 0.04 13.9 1.7 0.065 13.2 1.7 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) HemY_N PF07219.13 CAM43966.1 - 0.061 13.5 0.0 0.18 12.0 0.0 1.8 1 0 0 1 1 1 0 HemY protein N-terminus zf-RING_10 PF16685.5 CAM43966.1 - 0.073 13.2 3.8 0.12 12.5 3.8 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 CAM43966.1 - 0.2 11.5 4.8 0.34 10.7 4.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 CAM43966.1 - 0.35 10.5 6.1 0.61 9.8 6.1 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type TFIIA PF03153.13 CAM43966.1 - 0.43 10.5 7.6 0.72 9.8 7.6 1.2 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-RING_11 PF17123.5 CAM43966.1 - 1.8 8.4 7.1 0.99 9.2 3.6 2.3 2 1 0 2 2 2 0 RING-like zinc finger IBR PF01485.21 CAM43966.1 - 3 8.1 8.8 8.5 6.7 8.8 1.7 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Nucleoside_tran PF01733.18 CAM43967.1 - 3.9e-28 98.7 5.9 2.1e-27 96.3 5.9 2.0 1 1 0 1 1 1 1 Nucleoside transporter MutS_V PF00488.21 CAM43968.2 - 3.5e-55 187.0 0.7 6.3e-54 182.9 0.7 2.4 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CAM43968.2 - 5.8e-33 114.7 0.6 1.1e-32 113.8 0.6 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 CAM43968.2 - 2.2e-32 111.7 0.1 4.9e-32 110.5 0.1 1.7 1 0 0 1 1 1 1 MutS domain I AAA_29 PF13555.6 CAM43968.2 - 0.011 15.4 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 CAM43968.2 - 0.025 15.1 0.0 0.066 13.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 CAM43968.2 - 0.086 13.3 0.1 1.7 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain YgaB PF14182.6 CAM43968.2 - 2.7 8.4 3.8 3 8.3 0.5 2.3 2 0 0 2 2 2 0 YgaB-like protein TLD PF07534.16 CAM43969.1 - 2.3e-21 76.4 0.2 3.2e-20 72.8 0.2 2.2 1 1 0 1 1 1 1 TLD SICA_beta PF12878.7 CAM43969.1 - 0.074 13.2 0.4 0.74 10.0 0.0 2.3 2 0 0 2 2 2 0 SICA extracellular beta domain PMM PF03332.13 CAM43970.1 - 1.2e-99 332.6 1.4 1.3e-99 332.4 1.4 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 CAM43970.1 - 1.6e-08 34.6 0.0 4.6e-08 33.1 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CAM43970.1 - 7.7e-05 22.3 0.0 0.029 13.9 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase FliG_N PF14842.6 CAM43970.1 - 0.012 16.2 0.0 0.028 15.0 0.0 1.6 1 0 0 1 1 1 0 FliG N-terminal domain Hydrolase PF00702.26 CAM43970.1 - 0.096 13.0 0.1 0.16 12.2 0.1 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CAM43970.1 - 0.44 10.6 2.3 7.3 6.6 0.0 2.9 3 1 1 4 4 4 0 Haloacid dehalogenase-like hydrolase 2OG-FeII_Oxy_2 PF13532.6 CAM43971.1 - 5.2e-09 36.6 0.0 3.7e-08 33.8 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 CAM43971.1 - 0.0019 18.6 0.0 0.0034 17.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Metallophos PF00149.28 CAM43972.1 - 2.1e-17 64.3 0.0 3e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DNA_pol_phi PF04931.13 CAM43974.2 - 0.41 8.7 1.5 1.2 7.2 1.5 1.7 1 0 0 1 1 1 0 DNA polymerase phi FlxA PF14282.6 CAM43975.1 - 0.011 15.6 7.6 0.011 15.6 7.6 2.9 2 1 0 3 3 3 0 FlxA-like protein TPR_MLP1_2 PF07926.12 CAM43975.1 - 0.54 10.3 36.9 0.17 12.0 7.7 3.2 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein CSN5_C PF18323.1 CAM43975.1 - 1.2 10.1 9.5 3.4 8.7 0.1 2.6 2 1 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain Sigma70_ner PF04546.13 CAM43975.1 - 6.1 6.7 15.3 1.2 9.0 3.4 2.4 1 1 0 2 2 2 0 Sigma-70, non-essential region OmpH PF03938.14 CAM43975.1 - 6.5 7.1 28.0 2.7 8.3 9.7 2.2 1 1 0 2 2 2 0 Outer membrane protein (OmpH-like) UPF0184 PF03670.13 CAM43975.1 - 6.5 7.2 7.1 4.4 7.8 0.6 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) AAA_13 PF13166.6 CAM43975.1 - 9.7 4.7 17.4 3.1 6.3 4.9 2.0 1 1 1 2 2 2 0 AAA domain Cpn60_TCP1 PF00118.24 CAM43976.1 - 5.5e-85 285.9 14.5 1.1e-84 284.9 14.5 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.24 CAM43977.1 - 3e-86 290.0 15.5 5.9e-86 289.1 15.5 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family WD40 PF00400.32 CAM43978.1 - 2.2e-08 34.6 6.4 0.013 16.4 0.3 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ALG3 PF05208.13 CAM43979.1 - 1e-121 406.7 15.0 1.2e-121 406.5 15.0 1.0 1 0 0 1 1 1 1 ALG3 protein Metallophos PF00149.28 CAM43980.1 - 1e-16 62.1 0.0 1.3e-11 45.4 0.0 2.4 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase DUF72 PF01904.18 CAM43981.1 - 3.7e-30 105.7 0.1 4.3e-27 95.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function DUF72 TPR_2 PF07719.17 CAM43982.1 - 1.5e-12 46.6 6.6 4.6e-06 26.3 0.6 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CAM43982.1 - 4.7e-09 35.7 6.0 0.00058 19.6 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CAM43982.1 - 5.7e-08 32.3 1.5 0.037 13.7 0.3 3.9 3 1 1 4 4 4 3 TPR repeat TPR_8 PF13181.6 CAM43982.1 - 5.9e-07 29.2 0.7 0.00061 19.8 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 CAM43982.1 - 5.2e-05 23.4 1.9 0.072 13.4 0.3 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 CAM43982.1 - 0.002 18.7 3.3 0.002 18.7 3.3 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CAM43982.1 - 0.0044 17.7 1.6 0.0044 17.7 1.6 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 CAM43982.1 - 0.0047 16.8 0.3 0.072 13.2 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 CAM43982.1 - 0.055 13.6 4.9 1 9.5 1.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CAM43982.1 - 0.19 12.4 1.2 1.2 9.9 0.1 2.9 2 1 0 3 3 3 0 Tetratricopeptide repeat ATXN-1_C PF12547.8 CAM43982.1 - 0.46 10.8 2.3 0.52 10.7 0.1 2.2 3 0 0 3 3 3 0 Capicua transcriptional repressor modulator Avl9 PF09794.9 CAM43984.1 - 0.0022 16.8 0.0 0.004 15.9 0.0 1.4 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 CAM43984.1 - 0.005 16.8 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis F-actin_cap_A PF01267.17 CAM43984.1 - 0.02 14.4 0.1 0.03 13.8 0.1 1.3 1 0 0 1 1 1 0 F-actin capping protein alpha subunit Acetyltransf_10 PF13673.7 CAM43985.1 - 0.00091 19.2 0.1 0.025 14.5 0.0 2.3 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CAM43985.1 - 0.01 16.0 0.0 0.06 13.6 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family DnaJ PF00226.31 CAM43986.1 - 1.7e-22 79.3 0.5 2.6e-22 78.7 0.5 1.3 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 CAM43986.1 - 2.3e-06 27.8 1.2 2.5e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) DEAD PF00270.29 CAM43989.1 - 1.6e-48 164.8 0.0 3.1e-48 163.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAM43989.1 - 8.4e-32 109.8 0.1 3.1e-30 104.8 0.2 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAM43989.1 - 1.6e-05 24.9 0.0 0.0023 18.0 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CAM43989.1 - 0.00091 19.0 0.0 0.078 12.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain ERCC3_RAD25_C PF16203.5 CAM43989.1 - 0.0026 17.0 0.1 0.0038 16.5 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase EMP24_GP25L PF01105.24 CAM43991.1 - 4e-28 98.6 0.7 7.4e-28 97.7 0.7 1.4 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Dynein_light PF01221.18 CAM43992.1 - 3.5e-20 72.1 0.0 4.5e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 DUF3646 PF12362.8 CAM43992.1 - 0.0016 18.7 0.0 0.0022 18.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III gamma and tau subunits C terminal Alpha-amyl_C PF09071.10 CAM43992.1 - 0.046 13.6 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 Alpha-amylase, C terminal Methyltr_RsmB-F PF01189.17 CAM43993.1 - 3.6e-29 101.8 0.0 1.4e-21 77.1 0.0 3.0 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 CAM43993.1 - 0.011 15.9 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase Y_phosphatase PF00102.27 CAM43994.1 - 1.4e-43 149.2 0.0 2.5e-43 148.3 0.0 1.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CAM43994.1 - 7.6e-05 22.5 0.0 0.00016 21.5 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CAM43994.1 - 0.12 12.4 0.2 0.46 10.4 0.0 2.0 3 0 0 3 3 3 0 Tyrosine phosphatase family PRK PF00485.18 CAM43994.1 - 0.12 12.1 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family FA PF08736.11 CAM43995.1 - 0.064 13.4 0.3 0.38 10.9 0.3 2.4 1 0 0 1 1 1 0 FERM adjacent (FA) Choline_transpo PF04515.12 CAM43997.1 - 7.6e-65 219.2 32.4 7.6e-65 219.2 32.4 2.6 2 1 1 3 3 3 1 Plasma-membrane choline transporter DUF4234 PF14018.6 CAM43997.1 - 0.05 13.7 9.3 0.76 9.9 0.6 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) BRCT_2 PF16589.5 CAM43998.1 - 1.6e-06 28.4 0.0 0.053 13.9 0.0 2.6 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 CAM43998.1 - 0.00016 22.0 0.0 0.11 12.9 0.0 3.3 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CAM43998.1 - 0.0066 16.4 0.2 3 7.9 0.0 2.9 3 0 0 3 3 3 2 twin BRCT domain BRCT_3 PF18428.1 CAM43998.1 - 0.0088 16.1 0.1 2.2 8.4 0.0 2.5 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 CAM43998.1 - 0.13 12.5 0.2 34 4.8 0.0 2.8 3 0 0 3 3 3 0 DNA ligase 3 BRCT domain Sec1 PF00995.23 CAM43999.1 - 2.1e-104 350.9 0.1 2.6e-104 350.6 0.1 1.0 1 0 0 1 1 1 1 Sec1 family Corona_NSP4_C PF16348.5 CAM43999.1 - 0.18 12.7 0.7 10 7.0 0.1 3.3 2 1 1 3 3 3 0 Coronavirus nonstructural protein 4 C-terminus GCP_N_terminal PF17681.1 CAM44000.1 - 6.6e-16 58.8 0.0 3.5e-15 56.4 0.0 2.2 3 0 0 3 3 3 1 Gamma tubulin complex component N-terminal zf-C2H2_assoc PF16606.5 CAM44000.1 - 0.71 10.1 5.3 0.15 12.3 0.4 2.5 2 0 0 2 2 2 0 Unstructured conserved, between two C2H2-type zinc-fingers MMR_HSR1_Xtn PF16897.5 CAM44001.1 - 1.8e-42 143.6 0.0 4e-42 142.6 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 CAM44001.1 - 1.6e-19 70.1 0.0 3.4e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 CAM44001.1 - 9.7e-18 64.0 0.0 1.8e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 CAM44001.1 - 4.8e-09 35.9 0.0 1.6e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 CAM44001.1 - 0.0037 16.3 0.2 0.0096 14.9 0.1 1.7 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 CAM44001.1 - 0.11 12.5 0.2 4.5 7.3 0.0 2.3 1 1 0 2 2 2 0 Dynamin family Guanylate_kin PF00625.21 CAM44002.2 - 3.3e-39 134.5 0.0 4.7e-24 85.1 0.0 3.0 2 1 0 2 2 2 2 Guanylate kinase Rad17 PF03215.15 CAM44002.2 - 1.1e-05 25.4 0.0 1.8e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_33 PF13671.6 CAM44002.2 - 0.00018 21.7 0.1 0.011 16.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CAM44002.2 - 0.00038 20.4 0.0 0.00067 19.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 CAM44002.2 - 0.0045 17.4 0.0 0.0084 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 CAM44002.2 - 0.011 16.1 0.0 0.025 14.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 CAM44002.2 - 0.016 15.1 0.0 0.045 13.7 0.0 1.7 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 CAM44002.2 - 0.017 15.6 0.0 0.033 14.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 CAM44002.2 - 0.018 14.7 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CAM44002.2 - 0.02 14.9 0.0 0.056 13.5 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 CAM44002.2 - 0.024 14.4 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 CAM44002.2 - 0.029 14.6 0.0 0.25 11.6 0.0 2.2 1 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CAM44002.2 - 0.029 14.3 0.0 0.17 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CAM44002.2 - 0.052 13.1 0.0 0.093 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 CAM44002.2 - 0.053 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 CAM44002.2 - 0.073 13.5 0.0 1.9 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CAM44002.2 - 0.079 13.2 0.0 0.27 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CAM44002.2 - 0.087 13.4 0.0 0.43 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 CAM44002.2 - 0.092 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein G-alpha PF00503.20 CAM44002.2 - 0.13 11.4 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit AAA PF00004.29 CAM44002.2 - 0.14 12.5 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 CAM44002.2 - 0.15 11.2 0.1 0.46 9.6 0.0 1.9 2 1 0 2 2 2 0 NB-ARC domain TPR_1 PF00515.28 CAM44004.1 - 5.6e-30 101.9 5.1 0.00055 19.6 0.0 8.7 8 1 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.17 CAM44004.1 - 8.2e-26 88.0 14.9 0.0023 17.9 0.2 9.7 10 1 0 10 10 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 CAM44004.1 - 2.3e-25 86.6 1.4 8.8e-05 22.4 0.0 7.8 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 CAM44004.1 - 2.1e-21 75.3 1.0 6.5e-06 25.7 0.1 7.1 6 2 1 7 7 7 4 TPR repeat TPR_16 PF13432.6 CAM44004.1 - 8.7e-18 64.7 8.4 0.0035 18.0 0.0 7.0 4 3 3 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 CAM44004.1 - 2.2e-16 59.2 10.6 0.0013 19.4 0.0 8.0 4 3 5 9 9 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 CAM44004.1 - 2.6e-16 58.7 7.6 0.00061 20.0 0.0 8.7 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_12 PF13424.6 CAM44004.1 - 5e-16 58.8 18.7 6e-06 26.5 2.9 6.9 2 2 6 8 8 8 6 Tetratricopeptide repeat TPR_19 PF14559.6 CAM44004.1 - 8.6e-15 55.0 12.4 5.3e-06 26.9 0.5 6.0 4 2 3 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 CAM44004.1 - 2.3e-12 46.9 8.8 4.6e-06 26.7 0.1 4.9 3 1 2 6 6 6 4 Tetratricopeptide repeat TPR_6 PF13174.6 CAM44004.1 - 3.9e-11 42.8 9.6 2.1 9.2 0.6 8.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 CAM44004.1 - 1.9e-10 40.0 7.5 0.027 14.5 0.0 6.6 6 0 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CAM44004.1 - 3.1e-10 40.1 17.0 0.0018 18.5 0.0 5.6 3 3 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CAM44004.1 - 4e-07 29.7 12.0 0.0066 16.3 0.2 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_20 PF14561.6 CAM44004.1 - 6.2e-05 23.3 6.8 0.24 11.7 0.1 4.7 4 1 2 6 6 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 CAM44004.1 - 0.00014 22.1 13.8 0.0076 16.8 1.3 4.6 3 0 0 3 3 3 1 Tetratricopeptide repeat ChAPs PF09295.10 CAM44004.1 - 0.00017 20.7 0.3 0.024 13.6 0.0 3.3 1 1 2 4 4 4 1 ChAPs (Chs5p-Arf1p-binding proteins) BTAD PF03704.17 CAM44004.1 - 0.00021 21.7 5.6 0.05 14.0 0.1 4.2 3 2 2 5 5 5 1 Bacterial transcriptional activator domain NARP1 PF12569.8 CAM44004.1 - 0.00075 18.5 0.5 4.8 6.0 0.0 3.3 2 1 0 3 3 3 1 NMDA receptor-regulated protein 1 PknG_TPR PF16918.5 CAM44004.1 - 0.0017 17.2 0.2 0.0059 15.4 0.0 1.9 2 0 0 2 2 2 1 Protein kinase G tetratricopeptide repeat DUF3808 PF10300.9 CAM44004.1 - 0.0073 15.1 0.1 0.011 14.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) NatB_MDM20 PF09797.9 CAM44004.1 - 0.0094 14.9 1.3 0.61 9.0 0.1 2.2 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit Wzy_C_2 PF11846.8 CAM44004.1 - 0.0095 15.9 4.3 1.5 8.7 0.1 3.1 3 0 0 3 3 3 2 Virulence factor membrane-bound polymerase, C-terminal Paf67 PF10255.9 CAM44004.1 - 0.01 14.9 0.9 0.26 10.2 0.3 2.5 2 1 0 2 2 2 0 RNA polymerase I-associated factor PAF67 Alkyl_sulf_dimr PF14863.6 CAM44004.1 - 0.015 15.8 0.6 20 5.6 0.0 3.4 2 1 0 3 3 3 0 Alkyl sulfatase dimerisation Rotamase PF00639.21 CAM44005.1 - 4.1 8.4 5.1 2.6 9.1 0.1 2.3 1 1 0 2 2 2 0 PPIC-type PPIASE domain Ribosomal_S18 PF01084.20 CAM44006.1 - 0.00012 22.3 0.0 0.00028 21.1 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S18 Glucokinase PF02685.16 CAM44007.1 - 3.6e-14 52.5 0.0 1.7e-13 50.3 0.0 2.0 1 1 0 1 1 1 1 Glucokinase Endonuclease_5 PF04493.14 CAM44008.1 - 1.4e-54 184.8 0.0 1.9e-54 184.4 0.0 1.1 1 0 0 1 1 1 1 Endonuclease V adh_short PF00106.25 CAM44009.1 - 4.3e-14 52.4 1.4 5.3e-11 42.3 1.4 2.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CAM44009.1 - 1.6e-07 31.2 0.1 3.7e-05 23.4 0.0 2.3 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CAM44009.1 - 4.5e-05 23.4 2.2 0.00012 22.1 2.2 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CAM44009.1 - 0.013 14.9 0.3 0.039 13.4 0.1 1.8 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 CAM44009.1 - 0.031 14.4 0.0 0.088 13.0 0.0 1.8 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Polysacc_synt_2 PF02719.15 CAM44009.1 - 0.06 12.5 0.0 0.37 9.9 0.0 1.9 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.19 CAM44009.1 - 0.1 11.9 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Aminotran_1_2 PF00155.21 CAM44010.1 - 6.6e-60 203.2 0.0 8.3e-60 202.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CAM44010.1 - 0.0015 17.2 0.0 0.0023 16.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 CAM44010.1 - 0.096 11.9 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase PRIMA1 PF16101.5 CAM44011.1 - 3 7.9 22.3 0.46 10.5 0.3 4.3 4 0 0 4 4 4 0 Proline-rich membrane anchor 1 Sterol_MT_C PF08498.10 CAM44012.2 - 2.5e-22 78.9 0.1 5.1e-22 78.0 0.1 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 CAM44012.2 - 2.8e-17 63.2 0.3 9.7e-17 61.4 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAM44012.2 - 1.2e-14 54.7 0.1 7e-14 52.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAM44012.2 - 5.8e-12 45.6 0.0 1.4e-11 44.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAM44012.2 - 9.1e-09 35.4 0.0 1.9e-08 34.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAM44012.2 - 5.9e-08 33.4 0.1 2.4e-06 28.2 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 CAM44012.2 - 2.7e-07 30.2 0.0 4.6e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 CAM44012.2 - 5.8e-07 29.1 0.2 9.7e-07 28.3 0.2 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_15 PF09445.10 CAM44012.2 - 0.038 13.6 0.4 0.06 12.9 0.4 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase MTS PF05175.14 CAM44012.2 - 0.042 13.4 0.0 0.75 9.3 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain UPF0020 PF01170.18 CAM44012.2 - 0.065 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 EF-hand_7 PF13499.6 CAM44013.1 - 0.0005 20.5 0.0 0.00097 19.6 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CAM44013.1 - 0.0077 16.1 0.0 6.5 7.0 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CAM44013.1 - 0.01 15.3 0.0 3.4 7.5 0.0 2.4 2 0 0 2 2 2 0 EF hand RAG2_PHD PF13341.6 CAM44013.1 - 0.021 14.8 0.0 0.043 13.9 0.0 1.6 1 0 0 1 1 1 0 RAG2 PHD domain Cullin_Nedd8 PF10557.9 CAM44014.2 - 1.3e-15 57.2 0.3 2.4e-15 56.3 0.3 1.5 1 0 0 1 1 1 1 Cullin protein neddylation domain Phage_r1t_holin PF16945.5 CAM44014.2 - 0.51 10.6 3.3 1.5 9.1 0.0 3.2 3 0 0 3 3 3 0 Putative lactococcus lactis phage r1t holin Peptidase_S9 PF00326.21 CAM44015.1 - 5.7e-33 114.2 0.1 1.3e-32 113.0 0.1 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family DPPIV_N PF00930.21 CAM44015.1 - 9.7e-25 87.1 0.0 1.7e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Abhydrolase_6 PF12697.7 CAM44015.1 - 0.019 15.6 0.2 0.077 13.6 0.1 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 CAM44015.1 - 0.099 12.2 0.1 0.49 9.9 0.1 2.0 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Syntaxin PF00804.25 CAM44016.1 - 0.059 13.0 0.5 5.4 6.6 0.4 2.2 2 0 0 2 2 2 0 Syntaxin DUF742 PF05331.11 CAM44016.1 - 0.077 12.8 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF742) FYVE PF01363.21 CAM44017.1 - 0.00041 20.4 6.1 0.00041 20.4 6.1 1.8 3 0 0 3 3 3 1 FYVE zinc finger zf-B_box PF00643.24 CAM44017.1 - 0.24 11.6 5.2 1.3 9.2 2.0 2.3 2 0 0 2 2 2 0 B-box zinc finger SVIP PF15811.5 CAM44017.1 - 0.39 11.2 5.7 0.32 11.5 0.5 2.3 2 0 0 2 2 2 0 Small VCP/p97-interacting protein FYVE_2 PF02318.16 CAM44017.1 - 5.7 7.2 6.6 26 5.1 6.6 2.1 1 1 0 1 1 1 0 FYVE-type zinc finger His_Phos_2 PF00328.22 CAM44020.1 - 2.1e-11 43.8 1.1 2.6e-06 27.1 0.2 3.1 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) CAP_N PF01213.19 CAM44021.1 - 0.093 12.2 9.2 0.15 11.6 9.2 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RRM_1 PF00076.22 CAM44021.1 - 0.1 12.4 0.0 0.24 11.3 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Condensation PF00668.20 CAM44021.1 - 0.12 11.1 0.4 0.14 10.8 0.4 1.1 1 0 0 1 1 1 0 Condensation domain PRIMA1 PF16101.5 CAM44021.1 - 1.5 8.8 6.6 2.9 8.0 6.6 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 WD40 PF00400.32 CAM44023.1 - 7.4e-18 64.6 15.9 8.7e-07 29.6 1.0 5.9 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM44023.1 - 9.1e-09 35.5 0.7 9.4 6.6 0.0 5.4 5 0 0 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nic96 PF04097.14 CAM44024.2 - 3.7e-63 214.0 0.1 6.2e-63 213.2 0.1 1.3 1 0 0 1 1 1 1 Nup93/Nic96 Slx4 PF09494.10 CAM44024.2 - 0.071 13.1 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Slx4 endonuclease UTP15_C PF09384.10 CAM44024.2 - 0.092 12.4 1.0 1.2 8.8 0.0 3.1 4 0 0 4 4 4 0 UTP15 C terminal SNAPc_SNAP43 PF09808.9 CAM44025.1 - 0.00014 21.9 0.0 0.00021 21.3 0.0 1.2 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 DEAD PF00270.29 CAM44026.1 - 1.3e-24 86.9 0.0 2e-23 83.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAM44026.1 - 2.2e-24 86.0 0.0 1.1e-21 77.2 0.0 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 CAM44026.1 - 0.0077 16.5 0.1 4.1 7.7 0.0 2.7 1 1 1 2 2 2 2 AAA domain ResIII PF04851.15 CAM44026.1 - 0.0096 15.9 0.0 0.15 12.0 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 CAM44026.1 - 0.026 14.7 0.0 0.9 9.7 0.0 2.4 2 0 0 2 2 2 0 Helicase C-terminal domain NUC130_3NT PF08158.12 CAM44026.1 - 0.12 12.7 0.0 0.39 11.1 0.0 1.9 1 0 0 1 1 1 0 NUC130/3NT domain FA_hydroxylase PF04116.13 CAM44027.1 - 3.1e-21 76.1 16.9 3.1e-21 76.1 16.9 2.6 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily His_Phos_2 PF00328.22 CAM44028.1 - 3.5e-12 46.4 0.2 4.1e-08 33.0 0.0 3.0 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) HEAT PF02985.22 CAM44029.2 - 0.00051 20.1 2.1 3.5 8.1 0.1 4.3 3 0 0 3 3 3 2 HEAT repeat GDPD PF03009.17 CAM44031.1 - 5.1e-37 128.0 0.0 7.3e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family LPAM_2 PF13627.6 CAM44031.1 - 0.12 12.3 0.1 0.29 11.0 0.1 1.7 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site His_Phos_2 PF00328.22 CAM44032.1 - 3.2e-08 33.3 0.7 3.6e-05 23.3 0.0 3.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) RCC1 PF00415.18 CAM44033.1 - 2.9e-20 72.6 9.4 1.4e-05 25.7 0.1 5.9 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CAM44033.1 - 5.3e-20 70.7 15.1 4.6e-06 26.3 0.1 3.9 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat DUF4213 PF13938.6 CAM44033.1 - 0.39 11.0 5.9 14 6.0 0.1 3.8 4 1 0 4 4 4 0 Putative heavy-metal chelation Mur_ligase_M PF08245.12 CAM44034.1 - 1.2e-10 41.7 0.1 4.1e-10 40.0 0.1 1.9 1 1 0 1 1 1 1 Mur ligase middle domain Sulfatase PF00884.23 CAM44034.1 - 0.17 11.3 0.0 0.91 8.9 0.0 1.6 1 1 0 2 2 2 0 Sulfatase VRR_NUC PF08774.11 CAM44035.1 - 8.8e-08 32.2 0.0 2.1e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 VRR-NUC domain Pkinase PF00069.25 CAM44036.1 - 4.4e-23 82.0 0.0 1.7e-13 50.5 0.0 3.3 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM44036.1 - 1.4e-11 44.2 0.0 4e-10 39.4 0.0 2.5 2 0 0 2 2 2 1 Protein tyrosine kinase PCI PF01399.27 CAM44037.1 - 5.5e-05 23.6 0.0 0.091 13.3 0.0 3.2 3 0 0 3 3 3 2 PCI domain Methyltransf_11 PF08241.12 CAM44038.1 - 7e-11 42.6 0.0 5.7e-08 33.3 0.0 3.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAM44038.1 - 2.2e-10 41.1 0.0 0.00011 22.8 0.0 3.8 3 1 1 4 4 4 3 Methyltransferase domain Methyltransf_23 PF13489.6 CAM44038.1 - 6.3e-05 22.9 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAM44038.1 - 8e-05 23.3 0.0 0.00057 20.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAM44038.1 - 0.00011 22.0 0.0 0.44 10.3 0.0 3.1 3 0 0 3 3 3 2 Methyltransferase domain 2-oxoacid_dh PF00198.23 CAM44039.1 - 8.6e-77 257.7 0.0 1.2e-76 257.2 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.17 CAM44039.1 - 2.8e-12 46.8 0.3 8.5e-12 45.2 0.3 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl PF00364.22 CAM44039.1 - 3.6e-10 39.5 0.0 1.9e-09 37.2 0.0 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme TALPID3 PF15324.6 CAM44039.1 - 0.85 7.2 4.5 1.4 6.4 4.5 1.3 1 0 0 1 1 1 0 Hedgehog signalling target Metallophos_2 PF12850.7 CAM44040.1 - 2.4e-07 31.1 1.1 7.4e-06 26.2 1.1 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 CAM44040.1 - 1.9e-05 25.3 0.0 6.4e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase RIX1 PF08167.12 CAM44041.1 - 1.3e-05 25.0 2.0 8e-05 22.4 2.0 2.5 1 1 0 1 1 1 1 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.6 CAM44041.1 - 0.00034 21.0 3.4 0.2 12.2 0.0 4.7 4 1 1 5 5 5 2 HEAT-like repeat IBN_N PF03810.19 CAM44041.1 - 0.00036 20.4 0.1 0.013 15.4 0.1 3.2 1 1 0 1 1 1 1 Importin-beta N-terminal domain B56 PF01603.20 CAM44041.1 - 0.1 11.6 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Peptidase_M41 PF01434.18 CAM44042.1 - 5.8e-55 186.1 0.0 8.9e-55 185.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CAM44042.1 - 2.8e-41 141.0 0.0 5.4e-41 140.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAM44042.1 - 1.2e-06 28.1 0.9 5e-06 26.2 0.1 2.3 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 CAM44042.1 - 1.3e-05 25.2 0.0 3.8e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CAM44042.1 - 1.7e-05 25.3 0.1 0.00013 22.4 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CAM44042.1 - 2.6e-05 24.5 0.5 0.0017 18.7 0.5 2.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CAM44042.1 - 8.4e-05 22.4 0.0 0.00029 20.6 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 CAM44042.1 - 0.00019 21.1 0.6 0.062 12.9 0.2 2.4 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 CAM44042.1 - 0.00036 20.6 0.0 0.0013 18.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 CAM44042.1 - 0.001 18.3 0.0 0.0025 17.1 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 CAM44042.1 - 0.0011 19.5 0.0 0.0028 18.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CAM44042.1 - 0.0022 17.9 0.3 0.015 15.2 0.1 2.2 2 1 0 3 3 2 1 NACHT domain Rad17 PF03215.15 CAM44042.1 - 0.0023 17.9 0.0 0.005 16.8 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain IstB_IS21 PF01695.17 CAM44042.1 - 0.0027 17.4 0.0 0.0067 16.2 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.6 CAM44042.1 - 0.0038 17.7 0.0 0.0083 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CAM44042.1 - 0.0039 16.6 0.2 0.011 15.1 0.2 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 CAM44042.1 - 0.013 15.8 0.0 0.04 14.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 CAM44042.1 - 0.017 15.2 0.0 0.072 13.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) TsaE PF02367.17 CAM44042.1 - 0.021 14.8 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 CAM44042.1 - 0.028 14.8 0.0 0.11 12.9 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 CAM44042.1 - 0.028 14.6 0.0 0.062 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CAM44042.1 - 0.063 12.6 0.1 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 CAM44042.1 - 0.066 13.7 0.6 0.31 11.6 0.3 2.3 2 0 0 2 2 2 0 ABC transporter ATPase PF06745.13 CAM44042.1 - 0.083 12.2 0.0 0.72 9.2 0.0 2.4 3 0 0 3 3 3 0 KaiC DUF815 PF05673.13 CAM44042.1 - 0.14 11.3 0.0 0.33 10.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 CAM44042.1 - 0.23 10.5 0.0 0.41 9.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Peptidase_M50B PF13398.6 CAM44042.1 - 0.23 11.1 0.0 0.39 10.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like T3SSipB PF16535.5 CAM44044.1 - 0.064 13.7 7.1 2.8 8.4 0.1 2.2 2 0 0 2 2 2 0 Type III cell invasion protein SipB DUF2228 PF10228.9 CAM44044.1 - 0.11 12.2 2.0 0.23 11.1 2.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) Exonuc_VIII PF06630.11 CAM44044.1 - 0.19 11.5 0.7 0.39 10.6 0.1 1.8 2 0 0 2 2 2 0 Enterobacterial exodeoxyribonuclease VIII DUF648 PF04890.13 CAM44044.1 - 0.21 11.3 1.2 0.41 10.4 1.2 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF648) STAG PF08514.11 CAM44044.1 - 0.97 9.4 5.0 3.4 7.6 0.3 2.5 2 0 0 2 2 2 0 STAG domain Atg14 PF10186.9 CAM44044.1 - 3.8 6.5 11.8 1.1 8.3 3.3 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 CAM44044.1 - 6.3 6.8 6.6 0.98 9.5 1.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) MMS22L_C PF14911.6 CAM44046.2 - 0.024 13.7 0.0 0.059 12.5 0.0 1.6 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal Tyr_Deacylase PF02580.16 CAM44047.1 - 9.9e-43 146.1 0.0 1.1e-42 146.0 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Acetyltransf_1 PF00583.25 CAM44049.1 - 6.3e-17 61.9 0.1 8.5e-17 61.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CAM44049.1 - 1.1e-06 29.0 0.0 1.4e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CAM44049.1 - 1.3e-05 25.1 0.0 2.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CAM44049.1 - 0.00071 19.5 0.0 0.002 18.1 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.6 CAM44049.1 - 0.0011 19.1 0.0 0.0019 18.3 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_6 PF13480.7 CAM44049.1 - 0.002 18.3 1.1 0.0061 16.7 1.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3161 PF11362.8 CAM44049.1 - 0.012 15.5 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3161) Acetyltransf_9 PF13527.7 CAM44049.1 - 0.029 14.4 0.3 0.067 13.3 0.3 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_16 PF05301.11 CAM44049.1 - 0.18 11.6 0.1 0.28 11.0 0.1 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 MFS_1 PF07690.16 CAM44050.1 - 7.5e-12 44.8 46.1 1.1e-10 41.0 28.8 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Nodulin-like PF06813.13 CAM44050.1 - 4.4e-10 39.5 10.6 4.4e-10 39.5 10.6 2.5 2 0 0 2 2 2 1 Nodulin-like Saf_2TM PF18303.1 CAM44050.1 - 0.094 12.3 4.1 1.2 8.8 0.7 3.0 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain WTF PF03303.13 CAM44050.1 - 3.3 7.4 8.9 0.23 11.2 3.6 1.7 2 0 0 2 2 2 0 WTF protein TP6A_N PF04406.14 CAM44052.1 - 0.00041 20.3 0.0 0.011 15.7 0.0 2.4 2 0 0 2 2 2 1 Type IIB DNA topoisomerase NDK PF00334.19 CAM44053.2 - 0.00083 19.4 0.0 0.026 14.5 0.0 2.9 3 0 0 3 3 3 1 Nucleoside diphosphate kinase HA2 PF04408.23 CAM44057.1 - 2e-17 63.4 0.0 2e-17 63.4 0.0 2.6 3 0 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CAM44057.1 - 4.7e-17 62.1 0.0 2.7e-16 59.7 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CAM44057.1 - 6.9e-15 55.4 0.0 1.7e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CAM44057.1 - 2e-08 34.2 0.3 1.6e-07 31.3 0.1 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CAM44057.1 - 2.3e-05 24.7 0.5 0.00013 22.2 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CAM44057.1 - 0.00023 21.0 0.7 0.00064 19.5 0.1 2.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CAM44057.1 - 0.0085 15.8 0.1 1.3 8.8 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein Flavi_DEAD PF07652.14 CAM44057.1 - 0.072 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_19 PF13245.6 CAM44057.1 - 0.074 13.4 0.1 0.21 11.9 0.1 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CAM44057.1 - 0.079 13.5 0.2 1.1 9.8 0.2 2.7 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 CAM44057.1 - 0.11 12.0 0.0 0.34 10.4 0.0 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 CAM44057.1 - 0.12 12.9 0.0 0.12 12.9 0.0 2.7 3 1 0 3 3 2 0 AAA domain AAA_11 PF13086.6 CAM44057.1 - 9.3 5.9 10.1 25 4.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain OmpH PF03938.14 CAM44059.1 - 0.0043 17.4 4.4 0.0045 17.3 4.4 1.1 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) RasGAP_C PF03836.15 CAM44059.1 - 0.005 17.0 0.8 0.0053 16.9 0.8 1.2 1 0 0 1 1 1 1 RasGAP C-terminus TACC_C PF05010.14 CAM44059.1 - 0.005 16.6 2.8 0.0054 16.5 2.8 1.1 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal ATG16 PF08614.11 CAM44059.1 - 0.012 15.8 6.2 0.013 15.7 6.2 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) CCDC154 PF15450.6 CAM44059.1 - 0.013 14.1 2.6 0.013 14.0 2.6 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 154 Spc7 PF08317.11 CAM44059.1 - 0.015 14.2 4.4 0.016 14.1 4.4 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 CAM44059.1 - 0.019 14.3 3.5 0.023 14.1 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 CAM44059.1 - 0.027 15.0 6.6 0.032 14.7 6.6 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region UPF0242 PF06785.11 CAM44059.1 - 0.028 14.5 3.0 0.028 14.6 3.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF2968 PF11180.8 CAM44059.1 - 0.05 13.2 4.6 0.061 12.9 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) KxDL PF10241.9 CAM44059.1 - 0.058 13.7 2.5 0.083 13.2 1.9 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein YabA PF06156.13 CAM44059.1 - 0.067 13.8 2.3 0.14 12.8 2.3 1.5 1 1 0 1 1 1 0 Initiation control protein YabA RmuC PF02646.16 CAM44059.1 - 0.1 11.7 2.6 0.12 11.5 2.6 1.1 1 0 0 1 1 1 0 RmuC family GvpG PF05120.12 CAM44059.1 - 0.15 12.1 5.0 0.21 11.6 5.0 1.4 1 1 0 1 1 1 0 Gas vesicle protein G DUF484 PF04340.12 CAM44059.1 - 0.15 11.7 2.7 0.17 11.6 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF484 HAUS6_N PF14661.6 CAM44059.1 - 0.16 11.6 3.0 0.19 11.3 3.0 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Herpes_UL25 PF01499.16 CAM44059.1 - 0.2 10.1 1.6 0.24 9.9 1.6 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family GIT_CC PF16559.5 CAM44059.1 - 0.22 11.4 4.9 2 8.4 2.7 2.1 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor FUSC PF04632.12 CAM44059.1 - 0.22 10.0 1.2 0.22 10.0 1.2 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family ZapB PF06005.12 CAM44059.1 - 0.25 11.8 9.2 2.4 8.7 9.2 2.0 1 1 0 1 1 1 0 Cell division protein ZapB TMF_DNA_bd PF12329.8 CAM44059.1 - 0.3 11.1 7.8 0.62 10.1 7.8 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding TEX13 PF15186.6 CAM44059.1 - 0.33 10.6 4.7 0.41 10.3 4.7 1.1 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family LCD1 PF09798.9 CAM44059.1 - 0.34 9.4 3.0 0.39 9.2 3.0 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein V_ATPase_I PF01496.19 CAM44059.1 - 0.35 8.7 1.6 0.37 8.6 1.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4140 PF13600.6 CAM44059.1 - 1.4 9.4 5.8 2.3 8.7 5.8 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Spc24 PF08286.11 CAM44059.1 - 1.4 9.2 5.3 1.7 8.9 4.9 1.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DivIC PF04977.15 CAM44059.1 - 1.4 8.7 9.8 4.8 7.0 1.1 2.2 1 1 1 2 2 2 0 Septum formation initiator Lactamase_B_2 PF12706.7 CAM44060.1 - 0.096 12.2 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Ribosomal_S24e PF01282.19 CAM44061.1 - 1.9e-27 95.0 0.0 3.7e-27 94.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S24e ASH PF15780.5 CAM44062.1 - 3.2e-23 81.8 0.2 5.2e-05 23.4 0.0 9.3 10 0 0 10 10 10 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 CAM44062.1 - 9.1e-12 44.8 0.0 0.0057 16.5 0.0 6.4 7 0 0 7 7 7 2 MSP (Major sperm protein) domain TMEM131_like PF12371.8 CAM44062.1 - 0.001 19.3 0.1 1.7 8.9 0.0 4.4 5 0 0 5 5 5 1 Transmembrane protein 131-like DUF1573 PF07610.11 CAM44062.1 - 0.035 14.1 0.0 13 5.9 0.0 4.6 6 0 0 6 6 6 0 Protein of unknown function (DUF1573) MYCBPAP PF14646.6 CAM44062.1 - 0.09 11.7 0.0 22 3.8 0.0 3.5 4 0 0 4 4 4 0 MYCBP-associated protein family ABC2_membrane PF01061.24 CAM44063.1 - 3e-37 128.1 18.7 3e-37 128.1 18.7 1.6 2 0 0 2 2 1 1 ABC-2 type transporter ABC_tran PF00005.27 CAM44063.1 - 9.6e-24 84.5 0.0 1.6e-23 83.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CAM44063.1 - 2.7e-07 30.7 1.3 0.0062 16.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CAM44063.1 - 0.00076 19.0 0.0 0.0092 15.4 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CAM44063.1 - 0.0032 17.2 0.0 0.0085 15.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CAM44063.1 - 0.0065 16.4 0.3 0.018 14.9 0.1 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 CAM44063.1 - 0.0071 16.7 0.1 0.0071 16.7 0.1 1.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CAM44063.1 - 0.0082 16.4 0.1 0.053 13.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CAM44063.1 - 0.03 14.9 0.2 0.063 13.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 CAM44063.1 - 0.087 13.1 0.2 0.22 11.8 0.2 1.7 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 CAM44063.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_30 PF13604.6 CAM44063.1 - 0.19 11.5 2.1 0.32 10.7 0.3 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 CAM44063.1 - 0.2 12.1 0.2 0.36 11.3 0.2 1.3 1 0 0 1 1 1 0 AAA domain Pox_A9 PF04835.12 CAM44063.1 - 0.78 9.9 3.7 0.5 10.6 0.4 2.4 2 0 0 2 2 2 0 A9 protein conserved region MCM PF00493.23 CAM44064.1 - 2.7e-05 23.4 0.0 4.4e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain AAA_16 PF13191.6 CAM44064.1 - 0.0038 17.6 0.2 0.021 15.2 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain EccE PF11203.8 CAM44064.1 - 0.12 12.7 4.3 3.3 8.1 0.2 4.1 3 0 0 3 3 3 0 Putative type VII ESX secretion system translocon, EccE AAA PF00004.29 CAM44064.1 - 0.12 12.8 0.0 0.35 11.3 0.1 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PHF5 PF03660.14 CAM44066.1 - 8.2e-34 115.9 9.8 9.3e-34 115.8 9.8 1.0 1 0 0 1 1 1 1 PHF5-like protein FYVE_2 PF02318.16 CAM44066.1 - 0.34 11.1 9.3 0.15 12.3 7.2 1.5 2 0 0 2 2 2 0 FYVE-type zinc finger zf-C3HC4_3 PF13920.6 CAM44066.1 - 1.3 8.9 14.0 0.043 13.7 4.3 2.6 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 CAM44066.1 - 2 8.5 11.7 12 6.0 10.7 2.5 1 1 1 2 2 2 0 Double zinc ribbon TF_Zn_Ribbon PF08271.12 CAM44066.1 - 5.3 6.6 9.2 0.87 9.1 0.8 2.4 2 1 0 2 2 2 0 TFIIB zinc-binding zf-RING_2 PF13639.6 CAM44067.2 - 1.8e-12 47.4 2.1 1.8e-12 47.4 2.1 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 CAM44067.2 - 6.4e-10 38.6 0.7 1.3e-09 37.6 0.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CAM44067.2 - 1.7e-08 34.2 1.7 4e-08 33.0 1.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CAM44067.2 - 2e-07 30.8 0.6 2e-07 30.8 0.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CAM44067.2 - 5.4e-07 29.8 1.8 5.4e-07 29.8 1.8 2.0 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CAM44067.2 - 2.7e-06 27.3 1.1 2.7e-06 27.3 1.1 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CAM44067.2 - 4.5e-06 26.5 1.1 9.3e-06 25.5 1.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CAM44067.2 - 1.1e-05 25.1 1.0 1.1e-05 25.1 1.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CAM44067.2 - 0.005 16.4 1.9 0.015 14.9 1.9 1.8 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 CAM44067.2 - 0.018 15.1 2.6 0.085 12.9 2.6 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 CAM44067.2 - 0.22 11.7 2.6 0.85 9.8 2.6 2.1 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 CAM44067.2 - 0.34 10.7 1.5 0.83 9.5 1.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3H2C3 PF17122.5 CAM44067.2 - 0.45 10.6 2.7 1.1 9.4 2.7 1.6 1 0 0 1 1 1 0 Zinc-finger FANCL_C PF11793.8 CAM44067.2 - 0.5 10.6 6.9 0.44 10.8 2.6 2.9 2 1 0 2 2 2 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 CAM44067.2 - 0.83 9.6 7.4 0.077 12.9 2.2 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 PI3_PI4_kinase PF00454.27 CAM44068.2 - 2.8e-24 86.3 0.0 5.6e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase NUC194 PF08163.12 CAM44068.2 - 1.4e-05 24.2 0.0 0.0012 17.9 0.0 2.6 3 0 0 3 3 3 2 NUC194 domain FATC PF02260.20 CAM44068.2 - 0.0025 17.6 0.0 0.0084 15.9 0.0 2.1 1 0 0 1 1 1 1 FATC domain ATP-grasp_2 PF08442.10 CAM44069.1 - 4.1e-64 215.9 4.0 6.5e-64 215.2 4.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 CAM44069.1 - 1.2e-23 83.6 2.4 2.7e-23 82.5 0.9 2.3 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.6 CAM44069.1 - 0.03 14.1 0.5 0.071 12.9 0.5 1.6 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain KleE PF17394.2 CAM44070.1 - 0.035 14.3 0.7 0.048 13.9 0.4 1.3 1 1 0 1 1 1 0 Uncharacterized KleE stable inheritance protein DUF1430 PF07242.11 CAM44071.1 - 0.047 13.9 1.0 0.098 12.9 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1430) SYS1 PF09801.9 CAM44071.1 - 0.051 13.7 0.6 0.062 13.4 0.6 1.2 1 0 0 1 1 1 0 Integral membrane protein S linking to the trans Golgi network DUF4499 PF14934.6 CAM44071.1 - 0.054 13.8 0.5 0.15 12.4 0.2 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4499) DUF423 PF04241.15 CAM44071.1 - 0.068 13.4 2.9 0.13 12.5 0.2 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF423) Bromodomain PF00439.25 CAM44072.1 - 5.9e-22 77.5 0.0 9.3e-22 76.9 0.0 1.3 1 0 0 1 1 1 1 Bromodomain ANAPC15 PF15243.6 CAM44072.1 - 0.03 14.7 1.7 0.03 14.7 1.7 2.7 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 15 DUF1635 PF07795.11 CAM44072.1 - 0.21 11.4 1.4 0.33 10.8 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) TFIIA PF03153.13 CAM44072.1 - 3 7.8 12.0 3.2 7.6 12.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GTP1_OBG PF01018.22 CAM44073.1 - 1.2e-39 135.4 4.7 1.7e-39 134.9 4.7 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 CAM44073.1 - 4.4e-19 68.7 0.0 8.2e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CAM44073.1 - 3e-06 26.8 0.0 4.9e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B rRNA_proc-arch PF13234.6 CAM44074.2 - 2.5e-44 152.3 1.8 4.3e-44 151.5 0.9 1.8 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 CAM44074.2 - 4.3e-43 146.8 0.5 4.3e-43 146.8 0.5 2.3 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 CAM44074.2 - 2e-22 79.8 0.8 4.6e-21 75.4 0.0 2.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAM44074.2 - 7e-07 29.6 0.0 3.4e-06 27.4 0.0 2.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAM44074.2 - 1.1e-06 28.8 0.0 2.6e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 CAM44074.2 - 0.0012 18.8 1.0 0.028 14.3 0.0 2.5 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea FlxA PF14282.6 CAM44074.2 - 0.0027 17.7 4.3 0.0052 16.7 4.3 1.4 1 0 0 1 1 1 1 FlxA-like protein AAA_22 PF13401.6 CAM44074.2 - 0.015 15.6 0.0 0.08 13.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 CAM44074.2 - 0.021 14.3 0.0 0.052 13.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein T2SSE PF00437.20 CAM44074.2 - 0.043 12.9 0.0 0.11 11.5 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein Helicase_RecD PF05127.14 CAM44074.2 - 0.07 13.0 0.8 3.4 7.5 0.0 2.6 2 0 0 2 2 2 0 Helicase DUF3856 PF12968.7 CAM44074.2 - 0.094 12.8 0.8 13 5.8 0.0 2.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF3856) Zot PF05707.12 CAM44074.2 - 0.17 11.5 0.0 0.49 10.0 0.0 1.7 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) CobA_CobO_BtuR PF02572.15 CAM44074.2 - 0.3 11.4 1.7 1 9.6 0.0 2.7 4 0 0 4 4 4 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Syntaxin_2 PF14523.6 CAM44074.2 - 0.31 11.4 6.0 1.8 9.0 1.4 3.4 3 0 0 3 3 3 0 Syntaxin-like protein GSHPx PF00255.19 CAM44075.1 - 1.8e-26 91.8 0.0 2.2e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 CAM44075.1 - 0.0013 18.7 0.0 0.0018 18.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CAM44075.1 - 0.19 11.5 0.0 0.24 11.1 0.0 1.1 1 0 0 1 1 1 0 Redoxin RNase_PH PF01138.21 CAM44076.1 - 3.8e-28 98.6 1.6 4.9e-28 98.3 0.6 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CAM44076.1 - 6.2e-07 29.4 0.0 1.5e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF1623 PF07785.11 CAM44076.1 - 0.047 13.8 1.2 0.088 13.0 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1623) Adap_comp_sub PF00928.21 CAM44077.1 - 2e-54 184.8 0.0 2.4e-54 184.5 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CAM44077.1 - 2.6e-08 33.9 1.7 4.7e-08 33.1 1.7 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 CAM44077.1 - 0.039 13.4 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain DUF5314 PF17241.2 CAM44077.1 - 0.09 12.4 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5314) RRM_1 PF00076.22 CAM44078.1 - 7.2e-08 32.1 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CAM44078.1 - 1.1e-07 31.5 0.0 1.3e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phage_Gp23 PF10669.9 CAM44078.1 - 0.03 14.6 3.2 0.044 14.1 3.2 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Cullin PF00888.22 CAM44080.1 - 2.6e-64 218.0 0.0 3.1e-64 217.7 0.0 1.0 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CAM44080.1 - 5.6e-09 35.9 0.0 4e-08 33.2 0.0 2.4 2 0 0 2 2 2 1 Cullin protein neddylation domain Fibrillarin PF01269.17 CAM44081.1 - 6.3e-101 336.2 0.0 7.1e-101 336.0 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 CAM44081.1 - 0.00023 20.9 0.0 0.00031 20.5 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 CAM44081.1 - 0.013 15.3 0.1 0.023 14.5 0.1 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) BPL_LplA_LipB PF03099.19 CAM44082.1 - 0.037 13.9 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 Biotin/lipoate A/B protein ligase family Thioredoxin PF00085.20 CAM44083.2 - 0.039 13.9 0.0 0.26 11.3 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin T4_Gp59_N PF08993.10 CAM44083.2 - 0.12 12.8 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase vATP-synt_E PF01991.18 CAM44084.1 - 1e-38 132.8 5.9 1.2e-38 132.6 5.9 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Seipin PF06775.14 CAM44084.1 - 0.054 13.6 0.1 0.088 12.9 0.1 1.2 1 0 0 1 1 1 0 Putative adipose-regulatory protein (Seipin) Macscav_rec PF03523.13 CAM44085.1 - 0.12 12.3 0.2 0.27 11.1 0.2 1.5 1 0 0 1 1 1 0 Macrophage scavenger receptor BSD PF03909.17 CAM44085.1 - 0.15 12.1 0.1 0.4 10.7 0.1 1.7 1 0 0 1 1 1 0 BSD domain EF-hand_8 PF13833.6 CAM44086.1 - 0.00035 20.4 0.0 0.0055 16.5 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 CAM44086.1 - 0.0069 16.8 0.0 0.37 11.3 0.0 2.8 2 1 1 3 3 3 2 EF-hand domain pair Hexapep PF00132.24 CAM44086.1 - 0.12 12.2 0.5 0.54 10.1 0.1 2.4 2 0 0 2 2 2 0 Bacterial transferase hexapeptide (six repeats) Pro_isomerase PF00160.21 CAM44087.1 - 4.1e-37 127.9 0.0 4.6e-37 127.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ArfGap PF01412.18 CAM44089.2 - 3.2e-22 78.8 0.0 5.3e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf IRF-2BP1_2 PF11261.8 CAM44089.2 - 0.13 11.9 0.3 0.25 10.9 0.3 1.3 1 0 0 1 1 1 0 Interferon regulatory factor 2-binding protein zinc finger REV1_C PF16727.5 CAM44089.2 - 0.23 11.9 0.0 0.4 11.1 0.0 1.3 1 0 0 1 1 1 0 DNA repair protein REV1 C-terminal domain TBCC PF07986.12 CAM44090.1 - 2e-25 88.8 0.7 4.2e-25 87.8 0.7 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 CAM44090.1 - 0.0014 19.0 8.0 0.0024 18.3 8.0 1.3 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain TAN PF11640.8 CAM44090.1 - 0.0058 16.8 0.4 0.0097 16.1 0.4 1.3 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair CAP_C PF08603.11 CAM44090.1 - 0.14 11.8 0.2 0.28 10.8 0.2 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal DUF3395 PF11875.8 CAM44090.1 - 4.1 7.3 6.2 5.1 7.0 5.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3395) cobW PF02492.19 CAM44091.1 - 7.8e-47 159.1 0.1 1e-46 158.8 0.1 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 CAM44091.1 - 0.0047 16.8 0.0 0.0085 16.0 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 CAM44091.1 - 0.014 15.3 0.1 3.7 7.4 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_33 PF13671.6 CAM44091.1 - 0.048 13.8 0.0 0.087 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CAM44091.1 - 0.05 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.14 CAM44091.1 - 0.062 13.2 0.1 4.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 CAM44091.1 - 0.072 13.6 0.0 0.83 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain UPF0004 PF00919.20 CAM44091.1 - 0.079 13.0 1.5 0.18 11.9 0.4 2.0 2 0 0 2 2 2 0 Uncharacterized protein family UPF0004 AAA_22 PF13401.6 CAM44091.1 - 0.092 13.0 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 CAM44091.1 - 0.12 12.2 0.1 0.26 11.0 0.1 1.6 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein TsaE PF02367.17 CAM44091.1 - 0.13 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Guanylate_cyc PF00211.20 CAM44092.1 - 1.1e-37 129.4 0.0 2.3e-37 128.4 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF1935 PF09149.10 CAM44092.1 - 1.6e-27 95.9 0.0 3.4e-27 94.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) zf-CCHC PF00098.23 CAM44093.1 - 1.8e-18 65.7 78.4 0.00042 20.3 0.5 10.1 10 0 0 10 10 10 8 Zinc knuckle zf-CCHC_2 PF13696.6 CAM44093.1 - 6.4e-06 25.9 21.3 0.00078 19.2 2.0 9.6 8 1 1 9 9 9 4 Zinc knuckle NYN PF01936.18 CAM44093.1 - 0.17 12.3 0.0 0.42 11.1 0.0 1.7 1 1 0 1 1 1 0 NYN domain UPF0193 PF05250.11 CAM44093.1 - 0.21 11.4 0.2 0.54 10.0 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0193) zf-CCHC_4 PF14392.6 CAM44093.1 - 0.65 9.8 80.8 0.03 14.0 2.8 10.3 6 3 4 10 10 10 0 Zinc knuckle Topoisom_bac PF01131.20 CAM44094.2 - 2.9e-105 352.6 0.0 1.2e-104 350.7 0.0 1.8 2 0 0 2 2 2 1 DNA topoisomerase Toprim PF01751.22 CAM44094.2 - 2e-17 63.3 0.0 5.5e-17 61.9 0.0 1.8 2 0 0 2 2 2 1 Toprim domain zf-GRF PF06839.12 CAM44094.2 - 2.2e-06 27.6 1.2 2.2e-06 27.6 1.2 2.6 2 0 0 2 2 2 1 GRF zinc finger zf-C4_Topoisom PF01396.19 CAM44094.2 - 8.9e-06 25.4 0.1 8.9e-06 25.4 0.1 5.0 5 0 0 5 5 5 1 Topoisomerase DNA binding C4 zinc finger Cys_rich_CPCC PF14206.6 CAM44094.2 - 0.0056 16.5 2.0 0.059 13.2 1.1 2.8 3 0 0 3 3 3 1 Cysteine-rich CPCC Herpes_glycoH_C PF17488.2 CAM44094.2 - 0.058 13.2 0.1 14 5.5 0.0 2.5 2 0 0 2 2 2 0 Herpesvirus glycoprotein H C-terminal domain Terminase_GpA PF05876.12 CAM44094.2 - 1.5 7.3 3.1 2.4 6.6 3.1 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Cytochrom_c3_2 PF14537.6 CAM44094.2 - 3.8 8.0 6.0 18 5.9 0.3 2.9 2 0 0 2 2 2 0 Cytochrome c3 HypA PF01155.19 CAM44094.2 - 4.5 7.3 13.9 1.5 8.9 0.7 4.1 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 14-3-3 PF00244.20 CAM44095.1 - 2.4e-84 282.3 0.2 2.8e-84 282.1 0.2 1.0 1 0 0 1 1 1 1 14-3-3 protein CdvA PF18822.1 CAM44096.1 - 0.0063 16.3 4.3 0.0063 16.3 4.3 7.6 5 2 2 8 8 8 1 CdvA-like coiled-coil domain Lectin_N PF03954.14 CAM44096.1 - 0.0078 16.0 5.4 0.0078 16.0 5.4 6.5 1 1 4 6 6 6 1 Hepatic lectin, N-terminal domain HalX PF08663.10 CAM44096.1 - 0.027 14.8 4.1 0.027 14.8 4.1 8.9 4 4 5 9 9 9 0 HalX domain GMC_oxred_N PF00732.19 CAM44097.1 - 1.4e-48 165.8 0.1 2.1e-48 165.2 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CAM44097.1 - 1e-21 78.0 0.1 1.7e-21 77.3 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 CAM44097.1 - 4e-07 29.6 0.2 0.00037 19.8 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CAM44097.1 - 3e-05 23.3 8.2 0.0019 17.3 2.3 2.5 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 CAM44097.1 - 6.4e-05 22.7 9.5 0.00013 21.7 0.9 3.4 3 2 0 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 CAM44097.1 - 0.0015 17.7 1.6 0.063 12.4 1.6 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 CAM44097.1 - 0.0017 17.5 1.3 0.0029 16.7 1.3 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 CAM44097.1 - 0.0018 18.4 1.4 0.034 14.4 1.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CAM44097.1 - 0.0061 15.8 0.2 0.012 14.9 0.2 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 CAM44097.1 - 0.0064 15.9 1.0 0.15 11.4 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CAM44097.1 - 0.0065 15.2 1.2 0.011 14.5 1.2 1.3 1 0 0 1 1 1 1 HI0933-like protein ComFB PF10719.9 CAM44098.1 - 0.047 13.8 0.1 0.091 12.9 0.1 1.4 1 0 0 1 1 1 0 Late competence development protein ComFB dCache_1 PF02743.18 CAM44099.1 - 0.0014 18.5 0.5 0.0034 17.2 0.1 1.8 2 0 0 2 2 2 1 Cache domain DUF1712 PF08217.11 CAM44100.2 - 1.1e-05 24.2 0.0 2.9e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Fungal domain of unknown function (DUF1712) Ribosomal_L20 PF00453.18 CAM44101.1 - 0.028 14.5 0.9 0.047 13.8 0.9 1.4 1 0 0 1 1 1 0 Ribosomal protein L20 Ubiquitin_4 PF18036.1 CAM44101.1 - 0.03 14.4 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain UL42 PF17638.2 CAM44101.1 - 0.055 13.5 1.0 0.081 12.9 1.0 1.2 1 0 0 1 1 1 0 HCMV UL42 Ribosomal_L22e PF01776.17 CAM44102.1 - 1.2e-36 125.4 2.8 1.6e-36 125.0 2.8 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family ECH_2 PF16113.5 CAM44103.2 - 5.7e-24 85.2 0.0 3.4e-13 49.8 0.0 4.0 3 1 0 3 3 3 2 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CAM44103.2 - 2.7e-14 53.1 0.0 1.4e-09 37.7 0.0 2.3 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase EPO_TPO PF00758.18 CAM44103.2 - 0.017 15.1 0.0 0.052 13.6 0.0 1.8 1 1 1 2 2 2 0 Erythropoietin/thrombopoietin Macro PF01661.21 CAM44104.1 - 8.4e-05 22.6 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Macro domain Actin PF00022.19 CAM44106.1 - 6.9e-96 321.3 0.0 4.2e-95 318.8 0.0 1.8 1 1 0 1 1 1 1 Actin FtsA PF14450.6 CAM44106.1 - 0.06 13.8 0.1 0.42 11.1 0.0 2.2 2 1 0 2 2 2 0 Cell division protein FtsA DUF2644 PF10841.8 CAM44109.2 - 4.8 7.5 5.8 1.4 9.2 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2644) Bromodomain PF00439.25 CAM44111.1 - 4.7e-13 49.0 0.0 1.1e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Bromodomain Ribosomal_L29e PF01779.17 CAM44114.1 - 7e-13 48.7 4.7 7e-13 48.7 4.7 1.9 2 0 0 2 2 2 1 Ribosomal L29e protein family Ribosomal_L29e PF01779.17 CAM44115.1 - 7e-13 48.7 4.7 7e-13 48.7 4.7 1.9 2 0 0 2 2 2 1 Ribosomal L29e protein family adh_short PF00106.25 CAM44116.1 - 2e-36 125.3 0.0 2.7e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CAM44116.1 - 3.2e-14 53.1 0.0 4.8e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CAM44116.1 - 8.8e-11 42.0 1.6 2.1e-07 31.0 0.2 2.4 2 0 0 2 2 2 2 KR domain Methyltransf_31 PF13847.6 CAM44116.1 - 0.0016 18.3 0.0 0.0039 17.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain EPF PF17181.4 CAM44116.1 - 0.016 15.2 0.6 0.1 12.6 0.1 2.2 2 0 0 2 2 2 0 Epidermal patterning factor proteins Ubie_methyltran PF01209.18 CAM44116.1 - 0.071 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Pyr_redox PF00070.27 CAM44116.1 - 0.072 13.7 0.3 0.14 12.7 0.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1776 PF08643.10 CAM44116.1 - 0.083 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Vps26 PF03643.15 CAM44117.1 - 1.3e-54 185.1 0.3 1.7e-54 184.7 0.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 CAM44117.1 - 7.8e-05 22.8 1.1 0.42 10.7 0.0 3.2 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain CRAL_TRIO PF00650.20 CAM44118.2 - 4.6e-29 101.2 0.0 6.7e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CAM44118.2 - 0.017 15.3 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Snf7 PF03357.21 CAM44119.1 - 1.8e-28 99.3 27.2 1.8e-28 99.3 27.2 1.9 1 1 1 2 2 2 1 Snf7 MalF_P2 PF14785.6 CAM44119.1 - 0.048 13.7 3.7 0.077 13.0 3.7 1.3 1 0 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain Cdc13_OB4_dimer PF18233.1 CAM44119.1 - 0.064 13.4 0.7 0.12 12.5 0.7 1.5 1 0 0 1 1 1 0 Cdc13 OB4 dimerization domain Ferredoxin_N PF16947.5 CAM44119.1 - 3 8.0 5.9 0.28 11.3 0.6 2.0 2 0 0 2 2 2 0 N-terminal region of 4Fe-4S ferredoxin iron-sulfur binding MBF1 PF08523.10 CAM44119.1 - 6.2 7.4 8.2 2.1 8.9 2.5 2.6 2 1 1 3 3 3 0 Multiprotein bridging factor 1 Glyco_transf_25 PF01755.17 CAM44120.1 - 7.1e-12 45.6 0.0 3.5e-11 43.4 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) NIPSNAP PF07978.13 CAM44121.1 - 5.7e-15 55.4 0.1 1.6e-14 54.0 0.1 1.7 2 0 0 2 2 2 1 NIPSNAP Transket_pyr PF02779.24 CAM44122.1 - 1.3e-56 191.1 0.1 3.6e-56 189.7 0.0 1.8 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 CAM44122.1 - 1.4e-52 178.6 0.0 2.3e-52 177.8 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 CAM44122.1 - 3.3e-43 147.0 0.0 5.9e-43 146.2 0.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 CAM44122.1 - 5.1e-16 58.0 0.7 1.3e-15 56.7 0.7 1.7 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus SMAP PF15477.6 CAM44123.1 - 5.2e-09 36.9 6.9 5.2e-09 36.9 6.9 1.8 2 1 0 2 2 2 1 Small acidic protein family zf-U11-48K PF05253.12 CAM44123.1 - 8.5 6.4 6.0 1.7 8.7 2.1 1.9 2 0 0 2 2 2 0 U11-48K-like CHHC zinc finger DUF2870 PF11069.8 CAM44124.1 - 4.4e-26 91.1 0.0 1.3e-25 89.6 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) DUF1127 PF06568.11 CAM44124.1 - 0.26 11.1 2.4 0.71 9.6 2.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) DivIC PF04977.15 CAM44125.1 - 0.022 14.5 0.0 0.022 14.5 0.0 2.9 2 0 0 2 2 2 0 Septum formation initiator DUF3658 PF12395.8 CAM44125.1 - 0.035 14.0 0.8 2.3 8.2 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function Shugoshin_N PF07558.11 CAM44125.1 - 0.26 11.2 1.9 0.58 10.1 1.9 1.6 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Rota_NSP4 PF01452.16 CAM44125.1 - 0.26 10.9 2.6 0.51 10.0 2.6 1.4 1 0 0 1 1 1 0 Rotavirus non structural protein PTPlike_phytase PF14566.6 CAM44125.1 - 0.81 9.8 4.8 2.6 8.1 4.8 1.8 1 0 0 1 1 1 0 Inositol hexakisphosphate YabA PF06156.13 CAM44125.1 - 0.84 10.3 6.2 0.53 11.0 0.2 2.8 1 1 1 2 2 2 0 Initiation control protein YabA SidE PF12252.8 CAM44125.1 - 1 6.8 7.1 1.5 6.3 7.1 1.1 1 0 0 1 1 1 0 Dot/Icm substrate protein Prefoldin_2 PF01920.20 CAM44126.1 - 0.022 14.7 1.0 0.073 13.0 0.3 2.0 2 0 0 2 2 2 0 Prefoldin subunit Erythro-docking PF09277.11 CAM44126.1 - 1.1 9.2 5.4 3.7 7.5 0.1 3.0 3 1 0 3 3 3 0 Erythronolide synthase, docking COE1_DBD PF16422.5 CAM44127.1 - 0.02 14.3 0.1 0.029 13.8 0.1 1.1 1 0 0 1 1 1 0 Transcription factor COE1 DNA-binding domain DUF2150 PF09920.9 CAM44127.1 - 0.075 13.0 0.4 0.28 11.2 0.0 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) ubiquitin PF00240.23 CAM44128.1 - 0 1353.1 65.6 1e-31 108.5 0.2 13.0 13 0 0 13 13 13 13 Ubiquitin family Rad60-SLD PF11976.8 CAM44128.1 - 3e-206 667.7 67.9 2.9e-15 55.8 0.2 13.0 13 0 0 13 13 13 13 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CAM44128.1 - 7.1e-66 218.7 30.9 0.0028 18.1 0.0 15.8 13 12 0 13 13 13 13 Ubiquitin-like domain TBK1_ULD PF18396.1 CAM44128.1 - 2.1e-45 152.5 27.9 0.1 12.6 0.0 13.2 13 0 0 13 13 13 13 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CAM44128.1 - 6.5e-41 138.7 43.1 0.12 12.8 0.1 13.1 13 0 0 13 13 13 13 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CAM44128.1 - 2e-33 114.8 26.5 1 9.5 0.0 14.2 13 0 0 13 13 13 13 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CAM44128.1 - 1.1e-28 99.8 13.1 4.1 8.0 0.0 13.1 1 1 9 13 13 13 13 DUF2407 ubiquitin-like domain DUF2870 PF11069.8 CAM44128.1 - 5.3e-19 68.4 0.1 85 3.6 0.0 13.6 13 0 0 13 13 13 0 Protein of unknown function (DUF2870) UDP-g_GGTase PF06427.11 CAM44128.1 - 4.5e-16 58.9 29.1 14 5.8 0.0 12.5 13 0 0 13 13 13 0 UDP-glucose:Glycoprotein Glucosyltransferase Big_7 PF17957.1 CAM44128.1 - 2.4e-14 53.9 0.1 53 4.7 0.0 11.2 13 0 0 13 13 13 0 Bacterial Ig domain ORF11CD3 PF10549.9 CAM44128.1 - 3.1e-10 40.0 0.1 3.6e+02 1.4 0.0 12.3 13 0 0 13 13 13 0 ORF11CD3 domain DUF969 PF06149.12 CAM44128.1 - 4.4e-10 39.4 15.1 61 2.9 0.0 12.3 12 1 1 13 13 13 0 Protein of unknown function (DUF969) DUF3861 PF12977.7 CAM44128.1 - 3.8e-09 36.6 20.1 89 3.4 0.0 12.6 13 0 0 13 13 13 0 Domain of Unknown Function with PDB structure (DUF3861) Ubiquitin_4 PF18036.1 CAM44128.1 - 0.0023 17.9 91.5 69 3.6 0.2 24.4 26 0 0 26 26 26 0 Ubiquitin-like domain ProRS-C_2 PF09181.10 CAM44128.1 - 1.1 9.4 29.9 3.2e+02 1.5 0.1 11.7 13 0 0 13 13 13 0 Prolyl-tRNA synthetase, C-terminal TPR_1 PF00515.28 CAM44129.2 - 0.0018 18.0 0.1 0.0018 18.0 0.1 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF3846 PF12957.7 CAM44129.2 - 0.014 15.7 0.0 0.053 13.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3846) TPR_11 PF13414.6 CAM44129.2 - 0.019 14.6 0.5 5.6 6.7 0.3 3.1 3 0 0 3 3 3 0 TPR repeat TPR_9 PF13371.6 CAM44129.2 - 0.12 12.6 1.9 0.13 12.4 0.5 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 CAM44129.2 - 0.12 12.5 0.1 0.12 12.5 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat SQS_PSY PF00494.19 CAM44131.1 - 6.7e-13 48.7 0.0 9.7e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase TetR_C_20 PF17925.1 CAM44131.1 - 0.05 13.9 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain SRP54 PF00448.22 CAM44132.1 - 7.1e-55 185.7 0.1 1.7e-54 184.4 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 CAM44132.1 - 6e-19 69.1 0.1 1e-18 68.3 0.1 1.4 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.19 CAM44132.1 - 3.9e-09 36.6 0.0 8.2e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_22 PF13401.6 CAM44132.1 - 2e-06 28.1 0.0 1.2e-05 25.6 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.6 CAM44132.1 - 1.4e-05 24.9 0.1 2.7e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 CAM44132.1 - 0.00017 21.6 0.0 0.65 9.9 0.0 2.4 2 0 0 2 2 2 2 NTPase Zeta_toxin PF06414.12 CAM44132.1 - 0.00031 20.1 0.3 0.0063 15.8 0.0 2.7 2 2 1 3 3 3 1 Zeta toxin AAA_17 PF13207.6 CAM44132.1 - 0.0028 18.1 0.0 0.011 16.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CAM44132.1 - 0.0075 16.7 0.1 0.034 14.5 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain ArsA_ATPase PF02374.15 CAM44132.1 - 0.0075 15.5 0.1 0.039 13.1 0.0 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase ETF PF01012.21 CAM44132.1 - 0.013 15.4 0.1 0.32 10.9 0.0 2.3 2 0 0 2 2 2 0 Electron transfer flavoprotein domain NACHT PF05729.12 CAM44132.1 - 0.017 15.0 0.0 0.48 10.3 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 CAM44132.1 - 0.018 14.8 0.0 0.23 11.1 0.0 2.7 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CAM44132.1 - 0.021 14.9 1.1 0.56 10.3 0.6 3.1 3 1 0 3 3 3 0 50S ribosome-binding GTPase CbiA PF01656.23 CAM44132.1 - 0.022 14.8 0.0 0.099 12.7 0.0 2.2 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain APS_kinase PF01583.20 CAM44132.1 - 0.024 14.5 0.0 0.073 13.0 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase RsgA_GTPase PF03193.16 CAM44132.1 - 0.081 12.8 0.0 1.7 8.6 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase SCAB-PH PF17684.1 CAM44132.1 - 0.093 13.0 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 PH domain of plant-specific actin-binding protein DAP3 PF10236.9 CAM44132.1 - 0.094 11.9 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ABC_tran PF00005.27 CAM44132.1 - 0.12 12.9 0.0 0.29 11.7 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 CAM44132.1 - 0.13 12.5 0.1 0.38 10.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain DUF2009 PF09418.10 CAM44133.1 - 7.3e-158 526.4 0.0 8.5e-158 526.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) PALP PF00291.25 CAM44134.1 - 6.5e-60 203.0 1.4 7.4e-60 202.8 1.4 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PG_isomerase_N PF18353.1 CAM44134.1 - 0.065 13.6 0.0 0.17 12.3 0.0 1.8 1 1 0 1 1 1 0 Phosphoglucose isomerase N-terminal domain NUDE_C PF04880.13 CAM44135.1 - 2.4 8.6 6.9 2.7 8.4 0.7 2.3 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region EF-hand_7 PF13499.6 CAM44137.1 - 1.5e-09 38.2 0.2 2.4e-09 37.5 0.1 1.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 CAM44137.1 - 3.5e-05 23.6 0.1 0.046 13.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CAM44137.1 - 0.00024 20.8 0.0 0.11 12.4 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CAM44137.1 - 0.0055 16.2 0.0 1.2 8.8 0.0 2.6 2 0 0 2 2 2 2 EF hand Shisa PF13908.6 CAM44138.2 - 0.001 19.3 0.7 0.002 18.4 0.7 1.5 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator MLANA PF14991.6 CAM44138.2 - 0.036 14.3 0.0 0.065 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein melan-A Nitroreductase PF00881.24 CAM44138.2 - 0.038 14.1 0.1 0.056 13.5 0.1 1.4 1 0 0 1 1 1 0 Nitroreductase family DAG1 PF05454.11 CAM44138.2 - 0.041 13.3 0.2 0.068 12.5 0.2 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Neur_chan_memb PF02932.16 CAM44138.2 - 0.13 12.3 0.4 0.19 11.8 0.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region WD40 PF00400.32 CAM44140.1 - 9.4e-12 45.3 11.3 0.0085 16.9 0.2 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat NUDIX PF00293.28 CAM44141.1 - 3.7e-12 46.4 0.0 6.2e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain EF-hand_7 PF13499.6 CAM44143.1 - 1.5e-26 92.6 4.1 2.8e-13 50.1 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CAM44143.1 - 2.2e-24 83.1 9.6 4.3e-06 25.9 1.2 4.1 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CAM44143.1 - 5.6e-20 69.5 8.3 1.7e-05 24.3 0.2 4.5 4 2 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 CAM44143.1 - 6.3e-19 67.6 7.9 3.2e-09 36.5 0.7 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 CAM44143.1 - 1.5e-11 43.2 9.3 0.00091 18.6 0.8 4.3 4 1 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 CAM44143.1 - 2.5e-07 30.9 0.5 0.03 14.7 0.0 2.8 2 1 1 3 3 3 2 EF-hand domain EF-hand_4 PF12763.7 CAM44143.1 - 4.3e-05 23.4 4.8 0.0083 16.1 0.7 3.0 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 CAM44143.1 - 0.051 13.5 0.5 0.25 11.3 0.1 2.2 2 2 1 3 3 3 0 Caleosin related protein IFR3_antag PF14754.6 CAM44143.1 - 0.087 12.0 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Papain-like auto-proteinase Pkinase PF00069.25 CAM44144.1 - 5.6e-58 196.4 0.0 5.4e-57 193.2 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM44144.1 - 1e-31 110.2 0.0 3.7e-31 108.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase PAS PF00989.25 CAM44144.1 - 0.00013 21.9 0.0 0.00048 20.1 0.0 1.9 1 0 0 1 1 1 1 PAS fold Pkinase_fungal PF17667.1 CAM44144.1 - 0.0013 17.6 0.0 0.0028 16.5 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 CAM44144.1 - 0.0014 18.2 0.0 0.012 15.3 0.0 2.2 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 CAM44144.1 - 0.0029 17.6 0.0 0.0061 16.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family PAS_9 PF13426.7 CAM44144.1 - 0.0042 17.3 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 PAS domain Kinase-like PF14531.6 CAM44144.1 - 0.0093 15.3 0.0 0.085 12.2 0.0 2.2 2 0 0 2 2 2 1 Kinase-like DUF2721 PF11026.8 CAM44144.1 - 0.0098 15.8 2.0 0.025 14.4 2.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) FTA2 PF13095.6 CAM44144.1 - 0.01 15.5 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Amastin PF07344.11 CAM44144.1 - 0.025 14.4 3.6 0.065 13.1 3.6 1.7 1 0 0 1 1 1 0 Amastin surface glycoprotein OKR_DC_1_N PF03709.15 CAM44144.1 - 0.042 14.1 0.1 0.17 12.1 0.1 2.1 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain PAS_4 PF08448.10 CAM44144.1 - 0.045 14.0 0.0 2.4 8.4 0.0 2.5 2 0 0 2 2 2 0 PAS fold Kdo PF06293.14 CAM44144.1 - 0.15 11.4 0.1 0.3 10.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CLP1_P PF16575.5 CAM44147.1 - 5.1e-10 39.5 0.0 1.1e-08 35.1 0.0 2.2 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 CAM44147.1 - 0.00097 19.5 0.1 0.0026 18.2 0.0 1.7 2 0 0 2 2 2 1 Pre-mRNA cleavage complex II protein Clp1 FtsK_SpoIIIE PF01580.18 CAM44147.1 - 0.055 12.8 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family CLP1_N PF16573.5 CAM44147.1 - 0.055 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 N-terminal beta-sandwich domain of polyadenylation factor DUF498 PF04430.14 CAM44148.1 - 4.9e-19 68.4 0.0 9e-19 67.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) tRNA_int_endo PF01974.17 CAM44149.1 - 4.2e-15 55.6 0.0 6.6e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Ribosomal_L34e PF01199.18 CAM44150.1 - 3e-27 94.7 2.5 3e-27 94.7 2.5 2.2 2 1 0 2 2 2 1 Ribosomal protein L34e RecA PF00154.21 CAM44150.1 - 0.081 12.4 1.9 0.11 12.0 1.9 1.1 1 0 0 1 1 1 0 recA bacterial DNA recombination protein AAA_assoc_C PF09821.9 CAM44150.1 - 3.8 8.1 5.7 5 7.7 5.1 1.5 1 1 0 1 1 1 0 C-terminal AAA-associated domain Ribosomal_S27e PF01667.17 CAM44151.1 - 4.1e-22 77.7 3.0 5e-22 77.4 3.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 FYVE_2 PF02318.16 CAM44151.1 - 0.019 15.2 0.7 0.022 15.0 0.7 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger Zn_Tnp_IS1595 PF12760.7 CAM44151.1 - 0.023 14.7 1.8 0.037 14.0 1.8 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain HypA PF01155.19 CAM44151.1 - 0.12 12.4 1.8 0.14 12.2 1.8 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_4 PF13717.6 CAM44151.1 - 0.17 11.8 4.7 4.1 7.4 4.7 2.4 1 1 0 1 1 1 0 zinc-ribbon domain Ribosomal_L1 PF00687.21 CAM44152.1 - 4.2e-41 140.9 2.3 5.2e-41 140.6 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family NAC PF01849.18 CAM44153.1 - 3.3e-17 62.2 0.0 4.7e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 NAC domain Carbam_trans_N PF02543.15 CAM44153.1 - 0.061 13.0 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus MORN PF02493.20 CAM44154.1 - 2.4e-14 52.2 59.4 6.3e-05 22.6 1.2 9.5 10 0 0 10 10 10 7 MORN repeat DUF448 PF04296.13 CAM44154.1 - 0.05 13.5 5.1 11 6.0 0.0 4.9 5 3 1 6 6 6 0 Protein of unknown function (DUF448) DUF2766 PF10964.8 CAM44154.1 - 0.15 12.0 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2766) PPV_E2_N PF00508.17 CAM44154.1 - 1.9 7.8 9.4 0.65 9.3 2.1 2.3 2 0 0 2 2 2 0 E2 (early) protein, N terminal CH PF00307.31 CAM44155.1 - 0.00035 20.7 0.0 0.0008 19.6 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain Sipho_Gp157 PF05565.11 CAM44155.1 - 0.0029 17.6 0.3 0.0029 17.6 0.3 2.2 2 0 0 2 2 2 1 Siphovirus Gp157 CAMSAP_CH PF11971.8 CAM44155.1 - 0.15 11.9 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 CAMSAP CH domain DUF2277 PF10041.9 CAM44155.1 - 0.32 11.4 4.8 0.72 10.2 0.6 3.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2277) GCV_T PF01571.21 CAM44156.1 - 3.5e-79 265.8 0.3 4.3e-79 265.5 0.3 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 CAM44156.1 - 1.3e-20 73.1 0.8 2.8e-20 72.0 0.3 1.8 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain TolA_bind_tri PF16331.5 CAM44157.1 - 0.0051 16.8 2.6 0.0088 16.1 2.6 1.4 1 0 0 1 1 1 1 TolA binding protein trimerisation Gon7 PF08738.10 CAM44157.1 - 0.056 13.5 0.1 2.5 8.2 0.1 2.1 2 0 0 2 2 2 0 Gon7 family bZIP_2 PF07716.15 CAM44157.1 - 0.7 10.0 7.7 0.38 10.9 2.5 2.3 2 0 0 2 2 2 0 Basic region leucine zipper zf-C3HC4_3 PF13920.6 CAM44158.1 - 1.3e-17 63.4 35.9 7.3e-12 45.0 16.2 4.4 4 1 1 5 5 5 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CAM44158.1 - 7.7e-05 22.5 41.2 0.00023 20.9 15.2 3.6 3 1 1 4 4 4 2 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CAM44158.1 - 0.0037 17.2 44.8 0.004 17.1 16.6 4.2 4 0 0 4 4 4 2 zinc-RING finger domain zf-RING_2 PF13639.6 CAM44158.1 - 0.049 14.0 17.1 0.049 14.0 17.1 4.9 4 2 0 4 4 4 0 Ring finger domain HGTP_anticodon PF03129.20 CAM44159.1 - 6.3e-18 64.7 0.0 1.3e-17 63.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CAM44159.1 - 1e-06 28.8 0.0 4.6e-06 26.7 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Snf7 PF03357.21 CAM44160.1 - 7.2e-32 110.4 27.0 7.2e-32 110.4 27.0 1.5 2 0 0 2 2 2 1 Snf7 Fic_N PF13784.6 CAM44160.1 - 0.027 14.5 0.7 0.062 13.3 0.2 1.9 1 1 1 2 2 2 0 Fic/DOC family N-terminal DUF4407 PF14362.6 CAM44160.1 - 3.7 6.8 16.6 4.6 6.5 2.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) HAP2-GCS1 PF10699.9 CAM44161.2 - 7.9e-16 57.8 0.1 1.9e-15 56.6 0.1 1.7 1 0 0 1 1 1 1 Male gamete fusion factor Big_1 PF02369.16 CAM44161.2 - 0.05 13.6 1.0 1.2 9.2 0.1 3.0 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) Dicty_CTDC PF00526.18 CAM44161.2 - 0.4 10.6 6.1 1.4 8.9 0.0 3.3 4 0 0 4 4 4 0 Dictyostelium (slime mold) repeat LRR_6 PF13516.6 CAM44162.2 - 0.00071 19.4 0.1 0.47 10.6 0.0 3.1 3 0 0 3 3 3 2 Leucine Rich repeat WD40 PF00400.32 CAM44163.1 - 3.9e-14 52.8 3.1 0.00034 21.4 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM44163.1 - 9.9e-09 35.4 0.0 1.5 9.2 0.0 5.1 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CAM44163.1 - 0.032 13.2 0.0 0.16 10.9 0.0 2.2 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MAM33 PF02330.16 CAM44164.1 - 1.6e-05 24.9 0.0 6.5e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial glycoprotein DUF982 PF06169.12 CAM44165.1 - 0.026 14.5 1.9 0.074 13.1 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF982) AdoHcyase PF05221.17 CAM44166.1 - 6.4e-131 435.9 0.0 1.5e-73 247.5 0.0 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 CAM44166.1 - 1.9e-85 284.9 1.9 2.8e-85 284.3 1.9 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 CAM44166.1 - 1.7e-09 37.3 0.0 3.4e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 CAM44166.1 - 4.5e-05 23.1 0.1 7.8e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 CAM44166.1 - 0.0001 22.5 0.3 0.00046 20.4 0.2 2.3 2 1 0 2 2 2 1 TrkA-N domain NAD_binding_7 PF13241.6 CAM44166.1 - 0.00044 20.6 0.2 0.001 19.5 0.2 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding PALP PF00291.25 CAM44166.1 - 0.011 15.2 0.6 0.033 13.6 0.3 1.8 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme ELFV_dehydrog PF00208.21 CAM44166.1 - 0.051 13.3 0.0 0.095 12.4 0.0 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Oxidored_nitro PF00148.19 CAM44166.1 - 0.064 12.0 0.0 0.11 11.2 0.0 1.5 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase AdoHcyase PF05221.17 CAM44167.1 - 6.4e-131 435.9 0.0 1.5e-73 247.5 0.0 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 CAM44167.1 - 1.8e-85 284.9 1.8 2.6e-85 284.4 1.8 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 CAM44167.1 - 9.7e-10 38.1 0.0 1.9e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 CAM44167.1 - 3.8e-05 23.3 0.1 6.7e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 CAM44167.1 - 0.00011 22.5 0.4 0.00053 20.2 0.3 2.3 2 1 0 2 2 2 1 TrkA-N domain NAD_binding_7 PF13241.6 CAM44167.1 - 0.00042 20.7 0.2 0.00098 19.5 0.2 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding PALP PF00291.25 CAM44167.1 - 0.013 14.9 0.7 0.038 13.4 0.4 1.8 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme ELFV_dehydrog PF00208.21 CAM44167.1 - 0.051 13.3 0.0 0.094 12.4 0.0 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Telomerase_RBD PF12009.8 CAM44169.2 - 1.6e-22 80.1 0.0 3e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 CAM44169.2 - 0.00067 19.2 0.0 0.0018 17.8 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4719 PF15843.5 CAM44171.1 - 0.0089 16.2 6.2 0.01 16.0 4.5 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4719) Bacillus_HBL PF05791.11 CAM44171.1 - 0.14 11.9 3.8 0.14 12.0 0.2 2.3 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF5320 PF17253.2 CAM44171.1 - 1.5 9.9 13.0 0.33 12.0 6.5 2.9 2 1 0 2 2 2 0 Family of unknown function (DUF5320) CDC73_C PF05179.14 CAM44174.1 - 6.7e-32 110.3 0.0 9.8e-32 109.8 0.0 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal Proteasome PF00227.26 CAM44175.1 - 7e-25 87.6 0.3 1.8e-24 86.3 0.3 1.6 1 1 0 1 1 1 1 Proteasome subunit Rieske PF00355.26 CAM44176.1 - 0.014 15.3 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain V-SNARE_C PF12352.8 CAM44178.1 - 4.6e-07 30.0 1.3 4.6e-07 30.0 1.3 1.9 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus SSFA2_C PF14723.6 CAM44178.1 - 0.0017 18.3 2.7 0.0028 17.6 0.1 2.1 2 0 0 2 2 2 1 Sperm-specific antigen 2 C-terminus SesA PF17107.5 CAM44178.1 - 0.026 14.7 0.8 5.7 7.2 0.1 2.9 2 1 1 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases RD3 PF14473.6 CAM44178.1 - 0.048 13.5 1.1 0.29 11.0 0.1 2.4 2 0 0 2 2 2 0 RD3 protein Sec20 PF03908.13 CAM44178.1 - 0.13 12.2 0.4 0.53 10.2 0.1 2.1 2 1 1 3 3 3 0 Sec20 Peptidase_M14 PF00246.24 CAM44179.2 - 5.4e-16 59.2 0.0 2.7e-15 56.9 0.0 2.0 1 1 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 CAM44179.2 - 6.3e-08 32.0 0.1 1.1e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Pepdidase_M14_N PF18027.1 CAM44179.2 - 5.3e-07 30.0 0.0 1e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain TPR_2 PF07719.17 CAM44180.1 - 1.7e-05 24.6 4.1 1.6 9.0 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 CAM44180.1 - 0.0002 21.6 6.8 0.23 11.8 0.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CAM44180.1 - 0.0021 18.7 6.6 4.2 8.1 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 CAM44180.1 - 0.0024 17.6 1.4 1.7 8.6 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CAM44180.1 - 0.0062 16.5 4.7 1.2 9.4 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CAM44180.1 - 0.027 15.0 4.0 0.46 11.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 CAM44180.1 - 0.042 14.1 0.3 16 6.0 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CAM44180.1 - 0.35 11.6 2.2 4.9 8.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat WRNPLPNID PF15017.6 CAM44180.1 - 8.5 7.3 11.8 11 7.0 8.5 2.8 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box SKA1 PF07160.12 CAM44180.1 - 9.1 6.1 7.6 7.5 6.3 4.7 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 RCC1 PF00415.18 CAM44182.2 - 9.5e-38 128.6 13.5 6.4e-10 39.5 0.1 7.4 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CAM44182.2 - 1.1e-16 60.1 30.3 1.1e-06 28.2 3.2 7.5 6 2 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat His_Phos_1 PF00300.22 CAM44183.1 - 4.6e-14 52.6 7.3 2.1e-06 27.5 0.1 3.8 1 1 3 4 4 4 3 Histidine phosphatase superfamily (branch 1) DUF4398 PF14346.6 CAM44183.1 - 0.024 15.2 2.1 0.054 14.1 2.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) TarH PF02203.15 CAM44183.1 - 0.07 13.0 0.4 0.14 12.1 0.4 1.4 1 0 0 1 1 1 0 Tar ligand binding domain homologue CREPT PF16566.5 CAM44183.1 - 0.09 12.9 0.3 0.16 12.1 0.3 1.4 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour CPSase_L_D3 PF02787.19 CAM44183.1 - 0.095 13.1 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Smr PF01713.21 CAM44183.1 - 0.11 12.9 0.0 0.45 10.9 0.0 2.1 2 0 0 2 2 2 0 Smr domain FIVAR PF07554.13 CAM44183.1 - 0.13 13.1 0.9 0.22 12.3 0.9 1.3 1 0 0 1 1 1 0 FIVAR domain IQ PF00612.27 CAM44184.1 - 5.5e-14 50.6 8.3 0.0002 20.9 0.4 3.7 3 0 0 3 3 3 3 IQ calmodulin-binding motif Glyco_hydro_31 PF01055.26 CAM44186.1 - 2.3e-52 178.6 0.0 3.2e-52 178.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 MyTH4 PF00784.17 CAM44187.1 - 0.25 11.8 1.4 1.4 9.4 0.1 2.8 3 0 0 3 3 3 0 MyTH4 domain Amastin PF07344.11 CAM44189.1 - 1.7e-06 28.0 5.7 2.2e-06 27.6 5.7 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF4191 PF13829.6 CAM44189.1 - 0.77 9.0 1.8 0.87 8.9 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) MpPF26 PF07666.11 CAM44189.1 - 2.5 8.2 11.7 0.38 10.9 2.9 2.1 1 1 1 2 2 2 0 M penetrans paralogue family 26 Amastin PF07344.11 CAM44190.1 - 2.7e-14 53.3 6.8 5.1e-14 52.4 6.8 1.4 1 1 0 1 1 1 1 Amastin surface glycoprotein DUF2207 PF09972.9 CAM44190.1 - 2.5 6.8 8.2 0.38 9.5 1.5 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF4131 PF13567.6 CAM44190.1 - 9.6 5.8 7.9 2.5 7.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) TFIIS_C PF01096.18 CAM44191.1 - 1e-11 44.5 7.8 1e-11 44.5 7.8 2.5 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DUF1451 PF07295.11 CAM44191.1 - 0.02 14.9 0.3 0.02 14.9 0.3 2.4 2 1 0 2 2 2 0 Zinc-ribbon containing domain Baculo_LEF5_C PF11792.8 CAM44191.1 - 0.025 14.2 3.0 0.08 12.6 3.0 1.9 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain RNA_POL_M_15KD PF02150.16 CAM44191.1 - 0.16 11.9 5.6 16 5.5 0.1 3.7 4 0 0 4 4 4 0 RNA polymerases M/15 Kd subunit HypA PF01155.19 CAM44191.1 - 0.82 9.7 8.1 1.7 8.7 0.2 2.5 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-dskA_traR PF01258.17 CAM44191.1 - 3.1 7.8 6.2 8 6.5 0.0 3.2 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger TF_Zn_Ribbon PF08271.12 CAM44191.1 - 5.3 6.6 8.8 5.3 6.6 0.1 3.5 4 0 0 4 4 4 0 TFIIB zinc-binding Phage_lysozyme PF00959.19 CAM44192.2 - 0.039 14.4 0.0 0.15 12.5 0.0 2.1 1 0 0 1 1 1 0 Phage lysozyme Katanin_con80 PF13925.6 CAM44192.2 - 0.38 10.8 6.2 8.8 6.3 1.7 2.8 2 1 1 3 3 3 0 con80 domain of Katanin Lectin_N PF03954.14 CAM44192.2 - 3.6 7.3 8.7 0.23 11.2 2.0 2.5 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain ADH_zinc_N PF00107.26 CAM44194.2 - 5.1e-28 97.6 0.0 1.6e-27 96.0 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CAM44194.2 - 1.7e-16 61.5 0.0 3.7e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CAM44194.2 - 1.4e-12 47.4 0.1 3.5e-12 46.2 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 CAM44194.2 - 0.025 14.8 0.0 0.052 13.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Semialdhyde_dh PF01118.24 CAM44194.2 - 0.055 13.9 0.0 0.9 10.0 0.0 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Glycos_transf_4 PF00953.21 CAM44195.1 - 7.8e-48 162.5 6.3 7.8e-48 162.5 6.3 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 4 DUF2929 PF11151.8 CAM44195.1 - 0.22 11.9 2.3 2.6 8.4 0.2 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2929) Sld5 PF05916.11 CAM44196.1 - 6e-18 65.3 0.0 1e-17 64.6 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein Arrestin_N PF00339.29 CAM44197.1 - 1.3e-05 25.3 0.0 0.00039 20.5 0.0 2.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 CAM44197.1 - 5.8e-05 22.9 0.0 0.00016 21.4 0.0 1.7 1 0 0 1 1 1 1 Arrestin_N terminal like Spo0M PF07070.11 CAM44197.1 - 0.014 14.9 0.2 0.059 12.9 0.2 2.0 2 0 0 2 2 2 0 SpoOM protein UBA2_C PF16195.5 CAM44197.1 - 6.8 7.5 6.3 48 4.7 0.1 3.3 3 0 0 3 3 3 0 SUMO-activating enzyme subunit 2 C-terminus Utp21 PF04192.12 CAM44198.1 - 5.6e-25 88.2 0.0 8.5e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 CAM44198.1 - 4e-14 52.8 9.8 0.00081 20.2 0.0 8.8 10 0 0 10 10 10 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM44198.1 - 4.4e-11 42.9 0.1 0.0096 16.2 0.0 5.4 5 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CAM44198.1 - 0.00019 20.2 0.8 0.039 12.6 0.0 3.7 3 1 1 4 4 4 1 Nucleoporin Nup120/160 PQQ_2 PF13360.6 CAM44198.1 - 0.0021 17.7 5.1 0.33 10.5 0.8 3.2 2 2 0 2 2 2 2 PQQ-like domain Hira PF07569.11 CAM44198.1 - 0.0023 17.7 0.7 1.4 8.6 0.2 3.8 3 1 1 4 4 4 1 TUP1-like enhancer of split PALB2_WD40 PF16756.5 CAM44198.1 - 0.0041 16.1 3.7 0.028 13.3 0.1 3.2 4 0 0 4 4 4 1 Partner and localizer of BRCA2 WD40 domain Utp12 PF04003.12 CAM44198.1 - 0.011 16.1 0.0 0.025 14.9 0.0 1.5 1 0 0 1 1 1 0 Dip2/Utp12 Family HU-CCDC81_euk_2 PF18289.1 CAM44198.1 - 0.13 12.4 0.0 0.9 9.7 0.0 2.2 2 0 0 2 2 2 0 CCDC81 eukaryotic HU domain 2 PQQ_3 PF13570.6 CAM44198.1 - 8.8 7.0 8.2 24 5.6 0.1 5.1 6 0 0 6 6 6 0 PQQ-like domain DUF1298 PF06974.13 CAM44199.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) LRR_6 PF13516.6 CAM44200.1 - 2.3e-37 123.9 71.9 0.00075 19.4 0.1 21.4 23 1 1 24 24 24 13 Leucine Rich repeat LRR_4 PF12799.7 CAM44200.1 - 7.7e-10 38.9 54.9 0.012 16.1 0.6 14.2 12 3 4 17 17 17 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CAM44200.1 - 2.3e-05 24.3 25.8 95 4.2 0.0 15.9 19 1 0 19 19 19 0 Leucine Rich Repeat Suppressor_P21 PF11479.8 CAM44200.1 - 0.0015 18.7 2.5 8.4 6.7 0.0 3.9 3 0 0 3 3 3 2 RNA silencing suppressor P21 C-terminal domain AIMP2_LysRS_bd PF16780.5 CAM44200.1 - 0.019 14.7 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 AIMP2 lysyl-tRNA synthetase binding domain LRR_8 PF13855.6 CAM44200.1 - 0.23 11.3 54.7 1.7 8.5 1.3 12.9 10 4 5 15 15 15 0 Leucine rich repeat DUF4773 PF15998.5 CAM44200.1 - 9.6 6.8 7.8 6.5 7.3 0.2 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4773) WD40 PF00400.32 CAM44201.2 - 5.5e-06 27.0 1.7 0.61 11.1 0.0 5.0 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM44201.2 - 0.031 14.6 0.0 6.9 7.1 0.0 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 CAM44202.1 - 5.4e-45 153.8 0.0 4.9e-22 78.5 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM44202.1 - 2.9e-16 59.5 0.0 1.6e-09 37.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase HEAT PF02985.22 CAM44202.1 - 0.026 14.8 0.6 4.2 7.9 0.2 3.0 2 0 0 2 2 2 0 HEAT repeat Cor1 PF04803.12 CAM44203.1 - 0.82 9.9 17.3 0.16 12.2 9.9 2.6 1 1 0 2 2 2 0 Cor1/Xlr/Xmr conserved region TPR_14 PF13428.6 CAM44205.1 - 5e-12 45.6 54.6 0.014 16.2 0.2 12.5 11 3 3 14 14 13 7 Tetratricopeptide repeat TPR_19 PF14559.6 CAM44205.1 - 2.1e-10 41.0 15.4 0.00074 20.0 0.0 6.5 7 1 0 7 7 6 2 Tetratricopeptide repeat HAT PF02184.16 CAM44205.1 - 1.9e-08 34.1 10.2 0.12 12.3 0.1 5.6 5 0 0 5 5 5 3 HAT (Half-A-TPR) repeat TPR_16 PF13432.6 CAM44205.1 - 5.9e-06 26.8 28.7 0.18 12.5 0.1 8.0 7 0 0 7 7 7 3 Tetratricopeptide repeat DUF2063 PF09836.9 CAM44205.1 - 0.002 18.3 0.7 0.0091 16.2 0.3 2.4 2 0 0 2 2 2 1 Putative DNA-binding domain TPR_9 PF13371.6 CAM44205.1 - 0.0027 17.8 0.3 0.0027 17.8 0.3 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat NRDE-2 PF08424.10 CAM44205.1 - 0.011 14.9 0.7 0.3 10.1 0.1 3.0 2 1 0 2 2 2 0 NRDE-2, necessary for RNA interference TPR_2 PF07719.17 CAM44205.1 - 0.032 14.3 14.2 17 5.8 0.0 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CAM44205.1 - 0.043 13.8 3.1 18 5.3 0.1 5.3 5 1 0 5 5 5 0 Mad3/BUB1 homology region 1 SchA_CurD PF04486.12 CAM44205.1 - 0.098 12.8 0.1 1.1 9.3 0.1 2.6 1 1 1 2 2 2 0 SchA/CurD like domain TPR_6 PF13174.6 CAM44205.1 - 1.1 10.1 18.4 44 5.0 0.6 7.8 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.6 CAM44205.1 - 5.2 7.3 11.1 9.3 6.5 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat Arf PF00025.21 CAM44206.1 - 4.4e-11 42.6 0.0 7.8e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family PH PF00169.29 CAM44206.1 - 9.5e-09 35.7 0.0 2.2e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 CAM44206.1 - 0.016 15.5 0.1 0.081 13.2 0.2 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain MMR_HSR1 PF01926.23 CAM44206.1 - 0.068 13.2 0.0 0.36 10.9 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase C2 PF00168.30 CAM44208.1 - 3e-41 139.9 0.0 1.3e-11 44.7 0.0 8.5 9 0 0 9 9 9 6 C2 domain CEP76-C2 PF15627.6 CAM44208.1 - 0.063 12.8 0.2 26 4.3 0.0 3.6 3 0 0 3 3 3 0 CEP76 C2 domain Statherin PF03875.13 CAM44208.1 - 1.1 9.4 3.0 25 5.1 0.1 3.5 3 0 0 3 3 3 0 Statherin C2 PF00168.30 CAM44209.2 - 9e-15 54.8 0.0 0.01 16.1 0.1 4.5 4 0 0 4 4 4 4 C2 domain AAA PF00004.29 CAM44212.1 - 6.5e-44 149.6 0.0 1.4e-43 148.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAM44212.1 - 6.4e-15 54.7 0.3 2e-14 53.1 0.1 2.0 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 CAM44212.1 - 2.7e-07 30.6 0.1 9.9e-07 28.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CAM44212.1 - 3.4e-07 30.5 0.3 2.8e-06 27.6 0.0 2.5 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 CAM44212.1 - 1.3e-06 28.2 1.0 2.9e-06 27.1 1.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 CAM44212.1 - 1.4e-06 28.8 0.4 8.5e-05 23.0 0.0 2.9 2 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 CAM44212.1 - 1.8e-05 24.5 0.0 5e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CAM44212.1 - 2.5e-05 24.6 3.2 0.01 16.1 0.0 3.2 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 CAM44212.1 - 0.0004 20.9 0.2 0.013 16.0 0.0 2.7 3 1 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 CAM44212.1 - 0.0012 18.6 0.2 0.0033 17.2 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.6 CAM44212.1 - 0.0015 18.7 0.3 0.0033 17.6 0.0 1.9 2 1 0 2 2 1 1 AAA domain ATPase PF06745.13 CAM44212.1 - 0.0025 17.2 0.3 0.1 11.9 0.0 2.6 3 0 0 3 3 3 1 KaiC Sigma54_activat PF00158.26 CAM44212.1 - 0.0029 17.3 0.8 0.052 13.3 0.1 3.2 2 1 0 2 2 2 1 Sigma-54 interaction domain TIP49 PF06068.13 CAM44212.1 - 0.0032 16.7 0.0 0.016 14.4 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_28 PF13521.6 CAM44212.1 - 0.0045 17.2 0.2 0.014 15.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CAM44212.1 - 0.0063 16.1 0.6 0.17 11.5 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 CAM44212.1 - 0.0066 16.5 0.0 0.06 13.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CAM44212.1 - 0.0074 15.7 0.0 0.027 13.9 0.0 1.9 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 CAM44212.1 - 0.0089 15.2 0.4 0.4 9.8 0.0 2.5 3 0 0 3 3 3 1 NB-ARC domain AAA_3 PF07726.11 CAM44212.1 - 0.01 15.7 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CAM44212.1 - 0.012 16.0 0.0 0.026 14.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF815 PF05673.13 CAM44212.1 - 0.012 14.7 0.0 0.056 12.6 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF815) TsaE PF02367.17 CAM44212.1 - 0.013 15.5 0.0 0.031 14.3 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 CAM44212.1 - 0.015 14.6 0.5 0.16 11.3 0.0 2.5 2 1 1 3 3 3 0 Zeta toxin ADIP PF11559.8 CAM44212.1 - 0.015 15.4 1.4 0.031 14.4 1.4 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding AAA_11 PF13086.6 CAM44212.1 - 0.016 15.0 0.1 0.28 10.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CAM44212.1 - 0.02 14.4 0.0 0.048 13.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 CAM44212.1 - 0.022 14.5 0.1 0.061 13.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 CAM44212.1 - 0.028 13.9 0.1 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein APG6_N PF17675.1 CAM44212.1 - 0.029 14.9 0.3 0.062 13.8 0.3 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF4618 PF15397.6 CAM44212.1 - 0.046 13.1 1.0 0.12 11.8 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Parvo_NS1 PF01057.17 CAM44212.1 - 0.058 12.5 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DASH_Dad2 PF08654.10 CAM44212.1 - 0.073 13.5 0.5 0.21 12.0 0.5 1.8 1 0 0 1 1 1 0 DASH complex subunit Dad2 Prot_ATP_OB_N PF17758.1 CAM44212.1 - 0.088 12.5 0.1 0.27 10.9 0.1 1.8 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain AAA_19 PF13245.6 CAM44212.1 - 0.13 12.6 1.3 0.49 10.7 0.0 2.4 2 1 1 3 3 2 0 AAA domain NTPase_1 PF03266.15 CAM44212.1 - 0.27 11.1 2.6 2.9 7.8 0.0 3.2 3 1 0 3 3 3 0 NTPase DUF2968 PF11180.8 CAM44212.1 - 0.42 10.2 4.2 0.28 10.8 2.4 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF2968) HECT PF00632.25 CAM44213.2 - 5.2e-62 210.1 0.0 1.4e-60 205.4 0.0 2.5 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) L_lactis_RepB_C PF06430.12 CAM44213.2 - 0.15 12.0 0.1 0.3 11.1 0.1 1.4 1 0 0 1 1 1 0 Lactococcus lactis RepB C-terminus AOX PF01786.17 CAM44214.1 - 6.3e-81 271.1 0.0 7.6e-81 270.8 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase zf-RING_13 PF17977.1 CAM44214.1 - 3.4 7.9 6.4 0.61 10.3 0.1 2.7 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain GCP_N_terminal PF17681.1 CAM44215.2 - 1.8e-26 93.5 0.0 3.9e-26 92.4 0.0 1.6 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 CAM44215.2 - 4.3e-21 75.7 0.3 8.9e-21 74.6 0.1 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal DEAD PF00270.29 CAM44216.1 - 7.9e-31 107.2 0.0 3.2e-30 105.2 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAM44216.1 - 2e-29 102.1 0.3 5.3e-28 97.6 0.2 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAM44216.1 - 0.011 15.7 0.0 0.066 13.2 0.0 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Peptidase_M16_M PF16187.5 CAM44216.1 - 0.088 12.1 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Middle or third domain of peptidase_M16 Nore1-SARAH PF16517.5 CAM44216.1 - 0.13 12.2 2.3 0.15 12.0 0.1 2.4 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain UvrD-helicase PF00580.21 CAM44216.1 - 0.13 11.8 0.0 0.13 11.8 0.0 2.3 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain Z1 PF10593.9 CAM44216.1 - 0.13 11.7 0.1 0.13 11.7 0.1 1.8 2 0 0 2 2 2 0 Z1 domain AAA_22 PF13401.6 CAM44216.1 - 0.22 11.8 2.5 22 5.3 0.0 3.5 4 1 1 5 5 5 0 AAA domain Stathmin PF00836.19 CAM44217.1 - 2.2 8.2 21.8 1.8 8.5 20.7 1.4 1 1 0 1 1 1 0 Stathmin family Ribosomal_L22e PF01776.17 CAM44218.1 - 1.2e-36 125.4 2.8 1.6e-36 125.0 2.8 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family Asparaginase PF00710.20 CAM44219.1 - 3.7e-36 124.5 0.0 5e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 CAM44219.1 - 1.3e-24 86.7 0.1 5.1e-24 84.7 0.1 1.8 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain TPR_19 PF14559.6 CAM44220.1 - 0.0013 19.2 0.1 0.45 11.1 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 CAM44220.1 - 0.0013 18.7 1.3 0.0031 17.5 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CAM44220.1 - 0.0017 18.6 7.7 0.0046 17.2 0.6 3.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 CAM44220.1 - 0.0054 17.4 0.6 0.087 13.5 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CAM44220.1 - 0.011 16.5 0.9 3.3 8.8 0.3 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 CAM44220.1 - 0.028 14.3 0.8 0.099 12.5 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CAM44220.1 - 0.03 14.5 0.8 0.95 9.7 0.1 2.7 3 0 0 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CAM44220.1 - 0.039 14.2 1.6 0.072 13.3 0.1 2.3 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 CAM44220.1 - 0.059 14.0 1.9 0.11 13.1 0.8 2.1 2 0 0 2 2 1 0 Tetratricopeptide repeat DUF4919 PF16266.5 CAM44220.1 - 0.063 13.2 0.0 6.5 6.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4919) TPR_12 PF13424.6 CAM44220.1 - 0.066 13.5 0.1 0.24 11.7 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2193 PF09959.9 CAM44220.1 - 0.16 10.4 0.0 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2193) Peptidase_M3 PF01432.20 CAM44221.1 - 7.8e-70 236.4 0.2 7.3e-56 190.3 0.3 2.0 2 0 0 2 2 2 2 Peptidase family M3 Peptidase_M32 PF02074.15 CAM44221.1 - 0.0079 15.0 0.4 0.013 14.3 0.4 1.2 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase ACP_PD PF04336.12 CAM44222.1 - 0.017 15.5 0.0 0.027 14.9 0.0 1.4 1 0 0 1 1 1 0 Acyl carrier protein phosphodiesterase DnaJ PF00226.31 CAM44223.1 - 1.4e-22 79.5 0.4 5.7e-22 77.6 0.1 2.2 2 0 0 2 2 2 1 DnaJ domain Aa_trans PF01490.18 CAM44224.2 - 4.8e-43 147.4 0.2 1.1e-35 123.1 0.0 2.5 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein MTS PF05175.14 CAM44225.1 - 6.8e-13 48.5 0.1 1e-09 38.2 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase small domain Methyltransf_31 PF13847.6 CAM44225.1 - 1.6e-08 34.4 0.0 4.6e-08 33.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAM44225.1 - 8.6e-08 32.8 0.0 2.5e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CAM44225.1 - 6.5e-07 29.0 0.0 1.4e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 CAM44225.1 - 0.00032 20.1 0.0 0.00052 19.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 CAM44225.1 - 0.0012 19.4 0.0 0.0028 18.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAM44225.1 - 0.0039 17.0 0.0 0.016 15.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 CAM44225.1 - 0.0059 16.6 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAM44225.1 - 0.0071 17.1 0.0 0.019 15.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 CAM44225.1 - 0.0083 16.1 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 CAM44225.1 - 0.0084 15.9 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Met_10 PF02475.16 CAM44225.1 - 0.0094 15.7 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein AviRa PF11599.8 CAM44225.1 - 0.013 14.9 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Methyltransf_15 PF09445.10 CAM44225.1 - 0.03 13.9 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase TRM PF02005.16 CAM44225.1 - 0.11 11.7 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase UPF0020 PF01170.18 CAM44225.1 - 2.3 7.9 3.8 49 3.5 3.8 2.7 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 DUF2870 PF11069.8 CAM44226.1 - 7.7e-36 122.4 0.5 1.2e-35 121.7 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2870) Nup54_C PF18437.1 CAM44226.1 - 0.093 12.6 0.7 0.21 11.5 0.7 1.6 1 0 0 1 1 1 0 Nup54 C-terminal interacting domain Ribosomal_L18 PF17135.4 CAM44227.1 - 2.3e-74 248.9 2.8 2.6e-74 248.7 2.8 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 CAM44227.1 - 0.00046 20.9 0.1 0.0014 19.3 0.1 1.9 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A ABC1 PF03109.16 CAM44229.1 - 5.4e-26 91.1 0.0 9.8e-26 90.3 0.0 1.4 1 0 0 1 1 1 1 ABC1 family AalphaY_MDB PF04611.12 CAM44229.1 - 0.017 15.2 0.0 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region Pkinase PF00069.25 CAM44229.1 - 0.035 13.5 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Alpha_kinase PF02816.18 CAM44230.1 - 3.1e-51 174.1 0.3 4e-51 173.8 0.3 1.1 1 0 0 1 1 1 1 Alpha-kinase family Alpha_kinase PF02816.18 CAM44231.1 - 1.4e-85 286.0 0.0 3.5e-42 144.6 0.0 3.2 3 0 0 3 3 3 3 Alpha-kinase family Alpha_kinase PF02816.18 CAM44232.1 - 2e-57 194.3 0.6 2.4e-57 194.0 0.6 1.1 1 0 0 1 1 1 1 Alpha-kinase family PSP1 PF04468.12 CAM44233.1 - 8.4e-27 93.3 0.7 1.7e-26 92.3 0.7 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region DASH_Spc34 PF08657.10 CAM44233.1 - 0.0018 18.1 0.4 0.0032 17.3 0.4 1.3 1 0 0 1 1 1 1 DASH complex subunit Spc34 zf-HC5HC2H PF13771.6 CAM44236.2 - 1.9e-09 37.7 3.8 1.9e-09 37.7 3.8 3.1 3 1 0 3 3 3 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CAM44236.2 - 2.8e-07 30.7 7.7 2.8e-07 30.7 7.7 3.0 2 2 0 2 2 2 1 PHD-zinc-finger like domain Pesticin PF16754.5 CAM44238.1 - 0.094 12.7 0.5 0.24 11.3 0.5 1.6 1 0 0 1 1 1 0 Bacterial toxin homologue of phage lysozyme, C-term GPW_gp25 PF04965.14 CAM44238.1 - 0.1 12.3 0.0 0.36 10.6 0.0 1.9 1 0 0 1 1 1 0 Gene 25-like lysozyme FliJ PF02050.16 CAM44238.1 - 6.7 7.0 15.6 1.7 8.9 0.5 2.6 2 1 0 2 2 2 0 Flagellar FliJ protein M3 PF09213.10 CAM44239.2 - 0.061 12.0 0.1 0.11 11.2 0.1 1.3 1 0 0 1 1 1 0 M3 Ham1p_like PF01725.16 CAM44240.1 - 5.8e-45 153.5 0.0 6.8e-45 153.3 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Peptidase_S9 PF00326.21 CAM44241.1 - 2.4e-08 33.7 0.1 8e-07 28.7 0.0 2.4 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 CAM44241.1 - 9.9e-07 28.8 0.1 3e-05 23.9 0.0 2.4 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 CAM44241.1 - 1.8e-06 27.6 1.9 1.7e-05 24.5 1.9 2.5 1 1 0 1 1 1 1 Esterase PHB depolymerase Esterase PF00756.20 CAM44241.1 - 0.0013 18.5 0.0 0.0094 15.6 0.0 2.0 1 1 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.18 CAM44241.1 - 0.01 15.4 0.1 0.46 10.0 0.0 2.9 2 1 1 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 CAM44241.1 - 0.034 13.4 0.1 3.7 6.8 0.0 3.0 2 1 1 3 3 3 0 Serine aminopeptidase, S33 FSH1 PF03959.13 CAM44241.1 - 0.038 13.6 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF1100 PF06500.11 CAM44241.1 - 0.23 10.2 0.0 0.37 9.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) RL10P_insert PF17777.1 CAM44242.1 - 3.5e-25 87.8 0.0 5.9e-25 87.1 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 CAM44242.1 - 4.5e-19 68.4 0.2 6.9e-19 67.8 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 VPS9 PF02204.18 CAM44243.1 - 3.5e-29 101.1 0.0 7.7e-29 100.0 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain HALZ PF02183.18 CAM44244.1 - 0.0053 16.9 0.3 0.0053 16.9 0.3 2.3 2 0 0 2 2 2 1 Homeobox associated leucine zipper Golgin_A5 PF09787.9 CAM44244.1 - 0.0077 15.7 5.3 0.028 13.9 5.1 1.8 1 1 0 1 1 1 1 Golgin subfamily A member 5 ZapB PF06005.12 CAM44244.1 - 0.01 16.3 8.2 0.084 13.3 1.0 2.2 1 1 1 2 2 2 0 Cell division protein ZapB FlaC_arch PF05377.11 CAM44244.1 - 0.064 13.7 3.2 6 7.3 0.1 2.9 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.12 CAM44244.1 - 0.065 13.3 0.1 0.077 13.0 0.1 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 CAM44244.1 - 0.069 13.3 0.5 0.087 13.0 0.5 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4201 PF13870.6 CAM44244.1 - 0.082 12.6 7.4 0.18 11.6 7.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) FlxA PF14282.6 CAM44244.1 - 0.14 12.2 4.0 0.32 11.0 1.0 2.1 1 1 0 2 2 2 0 FlxA-like protein DUF3450 PF11932.8 CAM44244.1 - 0.26 10.6 7.9 0.054 12.8 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Spc7 PF08317.11 CAM44244.1 - 0.61 8.9 7.6 0.71 8.7 7.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein YabA PF06156.13 CAM44244.1 - 0.66 10.6 5.7 0.74 10.5 0.9 2.1 1 1 1 2 2 2 0 Initiation control protein YabA bZIP_2 PF07716.15 CAM44244.1 - 1.4 9.1 10.5 4.9 7.3 1.4 2.8 2 1 0 2 2 2 0 Basic region leucine zipper TMF_DNA_bd PF12329.8 CAM44244.1 - 1.5 8.9 7.6 4 7.5 0.5 2.3 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding kleA_kleC PF17383.2 CAM44244.1 - 1.5 9.2 8.2 6 7.3 0.8 2.2 1 1 1 2 2 2 0 Uncharacterized KorC regulated protein A DivIC PF04977.15 CAM44244.1 - 2 8.2 5.6 3.6 7.4 1.8 2.4 2 1 1 3 3 3 0 Septum formation initiator CCDC-167 PF15188.6 CAM44244.1 - 4.3 7.8 8.7 23 5.4 0.4 2.2 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 SlyX PF04102.12 CAM44244.1 - 4.4 8.0 8.3 26 5.5 2.6 2.7 1 1 2 3 3 3 0 SlyX Cyt-b5 PF00173.28 CAM44245.1 - 3.6e-14 52.6 0.0 4.1e-14 52.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Abhydrolase_1 PF00561.20 CAM44247.1 - 0.005 16.5 0.0 3.1 7.4 0.0 3.0 3 0 0 3 3 3 2 alpha/beta hydrolase fold DUF3123 PF11321.8 CAM44247.1 - 2.9 8.6 6.9 0.93 10.2 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3123) WD40 PF00400.32 CAM44248.1 - 7.8e-11 42.4 7.0 0.078 13.9 0.1 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM44248.1 - 9.3e-09 35.5 0.0 0.42 10.9 0.0 4.4 3 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Flavodoxin_1 PF00258.25 CAM44249.2 - 1.2e-43 148.7 0.0 2.1e-24 86.4 0.0 5.9 6 0 0 6 6 6 4 Flavodoxin FAD_binding_1 PF00667.20 CAM44249.2 - 8.9e-18 64.7 0.0 1.6e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 CAM44249.2 - 5e-11 43.2 0.0 2.6e-10 40.9 0.0 2.3 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain RabGAP-TBC PF00566.18 CAM44250.2 - 0.032 13.9 0.1 0.093 12.4 0.1 1.8 1 1 0 1 1 1 0 Rab-GTPase-TBC domain AvrM_N PF18247.1 CAM44250.2 - 0.13 12.2 0.2 0.26 11.2 0.2 1.4 1 0 0 1 1 1 0 Flax-rust effector AvrM N-terminal domain Z1 PF10593.9 CAM44250.2 - 0.44 10.0 2.4 0.94 8.9 2.4 1.4 1 0 0 1 1 1 0 Z1 domain CAMSAP_CH PF11971.8 CAM44251.2 - 0.1 12.5 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 CAMSAP CH domain PIG-P PF08510.12 CAM44252.1 - 6.4e-28 97.1 1.2 6.4e-28 97.1 1.2 1.8 2 0 0 2 2 2 1 PIG-P Peptidase_U4 PF03419.13 CAM44252.1 - 0.012 15.0 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA DPM2 PF07297.12 CAM44252.1 - 0.033 14.5 7.2 0.033 14.5 7.2 2.2 2 1 0 2 2 2 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) FAST_1 PF06743.15 CAM44253.1 - 0.11 12.4 0.2 33 4.5 0.0 3.7 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 1 Retrotran_gag_2 PF14223.6 CAM44254.1 - 0.079 12.6 0.1 0.2 11.3 0.1 1.7 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF1749 PF08538.10 CAM44255.2 - 2.2e-12 46.7 0.1 3.2e-12 46.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Spermine_synth PF01564.17 CAM44257.1 - 0.00042 19.8 0.0 0.0007 19.1 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_24 PF13578.6 CAM44257.1 - 0.033 15.2 0.0 0.09 13.8 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_30 PF05430.11 CAM44257.1 - 0.043 13.7 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_23 PF13489.6 CAM44257.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PPR_2 PF13041.6 CAM44258.1 - 5.6e-38 128.9 4.4 2.9e-15 56.2 0.7 5.1 3 1 2 5 5 5 5 PPR repeat family PPR_3 PF13812.6 CAM44258.1 - 4.2e-33 113.2 0.2 1.1e-12 47.8 0.2 5.1 2 1 3 5 5 5 4 Pentatricopeptide repeat domain PPR PF01535.20 CAM44258.1 - 3.2e-32 108.5 0.7 4e-06 26.7 0.0 6.0 6 0 0 6 6 6 5 PPR repeat PPR_1 PF12854.7 CAM44258.1 - 8.5e-27 92.6 0.1 1.7e-08 34.0 0.1 6.1 6 0 0 6 6 6 5 PPR repeat PPR_long PF17177.4 CAM44258.1 - 1.9e-19 69.9 0.4 1.3e-14 54.1 0.1 2.5 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 CAM44258.1 - 3.9e-06 27.2 0.3 15 6.7 0.0 5.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 CAM44258.1 - 0.046 13.8 0.0 21 5.4 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat WD40 PF00400.32 CAM44259.1 - 6.4e-37 124.9 11.2 1.2e-06 29.1 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM44259.1 - 1.3e-06 28.6 0.0 0.74 10.2 0.0 5.2 3 1 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CAM44259.1 - 0.014 14.8 0.0 0.073 12.4 0.0 2.0 1 1 0 2 2 2 0 WD40-like domain Roc PF08477.13 CAM44260.1 - 0.00042 20.5 0.1 0.018 15.2 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 CAM44260.1 - 0.0067 16.8 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain MttA_Hcf106 PF02416.16 CAM44260.1 - 0.23 10.8 0.8 6.7 6.1 0.0 2.4 2 0 0 2 2 2 0 mttA/Hcf106 family LRR_4 PF12799.7 CAM44261.2 - 3.6e-28 97.1 45.1 0.00087 19.6 0.3 14.2 10 4 5 16 16 16 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM44261.2 - 4.2e-08 32.8 31.8 0.00053 19.7 1.8 8.9 5 3 3 9 9 9 2 Leucine rich repeat LRR_6 PF13516.6 CAM44261.2 - 6e-05 22.8 39.0 0.016 15.2 0.3 12.3 14 0 0 14 14 14 3 Leucine Rich repeat LRR_9 PF14580.6 CAM44261.2 - 0.0014 18.2 6.7 1.2 8.6 0.1 4.4 2 2 0 3 3 3 3 Leucine-rich repeat Sec2p PF06428.11 CAM44262.1 - 0.0048 16.8 2.9 0.16 12.0 0.2 2.9 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p FlaC_arch PF05377.11 CAM44262.1 - 0.027 14.9 1.5 7.1 7.1 0.1 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) LXG PF04740.12 CAM44262.1 - 0.035 13.8 3.6 0.48 10.1 0.1 3.1 3 0 0 3 3 3 0 LXG domain of WXG superfamily DASH_Duo1 PF08651.10 CAM44262.1 - 0.16 11.8 0.7 6.3 6.6 0.1 3.1 3 0 0 3 3 3 0 DASH complex subunit Duo1 CENP-Q PF13094.6 CAM44262.1 - 0.5 10.6 11.3 0.42 10.8 0.3 3.0 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Spc29 PF17082.5 CAM44262.1 - 1.1 9.1 3.9 0.26 11.1 0.1 1.9 3 0 0 3 3 3 0 Spindle Pole Component 29 2_5_RNA_ligase2 PF13563.6 CAM44263.1 - 0.04 13.8 0.0 0.13 12.1 0.1 1.9 1 1 1 2 2 2 0 2'-5' RNA ligase superfamily DUF1045 PF06299.12 CAM44263.1 - 0.097 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) AFP PF02420.15 CAM44263.1 - 0.5 10.9 0.1 0.5 10.9 0.1 2.6 3 0 0 3 3 3 0 Insect antifreeze protein repeat MtN3_slv PF03083.16 CAM44264.2 - 2e-21 75.8 20.0 8.4e-14 51.4 0.6 2.6 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange DUF1003 PF06210.11 CAM44264.2 - 7.7 6.7 7.9 11 6.2 2.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1003) LRR_9 PF14580.6 CAM44265.1 - 7.9e-14 51.5 0.0 1.7e-10 40.6 0.1 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 CAM44265.1 - 2.3e-12 46.9 11.5 0.00013 22.3 0.3 4.3 3 2 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM44265.1 - 6.6e-12 45.0 13.8 8.2e-07 28.7 1.1 3.8 1 1 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 CAM44265.1 - 0.0037 17.2 15.8 0.01 15.8 0.3 5.0 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.33 CAM44265.1 - 1.8 9.4 13.1 9.2 7.3 0.0 5.7 6 0 0 6 6 6 0 Leucine Rich Repeat RNase_PH PF01138.21 CAM44266.1 - 3.7e-15 56.6 0.4 7.4e-15 55.6 0.4 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Clathrin PF00637.20 CAM44267.1 - 1.5e-07 31.4 0.1 1.5e-07 31.4 0.1 2.2 3 0 0 3 3 3 1 Region in Clathrin and VPS Vps8 PF12816.7 CAM44267.1 - 7.7e-05 22.3 0.0 3.8 7.0 0.0 4.2 4 0 0 4 4 4 3 Golgi CORVET complex core vacuolar protein 8 zf-RING_2 PF13639.6 CAM44267.1 - 0.0071 16.7 1.9 0.021 15.1 1.9 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CAM44267.1 - 0.0095 15.8 1.6 0.024 14.5 1.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 CAM44267.1 - 0.083 13.0 1.4 0.24 11.5 1.4 1.7 1 0 0 1 1 1 0 Zinc-finger zf-rbx1 PF12678.7 CAM44267.1 - 0.33 11.3 4.8 0.77 10.1 4.8 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain RskA PF10099.9 CAM44268.1 - 0.0025 18.2 0.8 0.015 15.6 0.8 2.1 1 1 0 1 1 1 1 Anti-sigma-K factor rskA CH PF00307.31 CAM44269.2 - 1.6e-11 44.4 0.0 2.8e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain IF-2B PF01008.17 CAM44270.1 - 1.2e-71 241.2 0.1 1.4e-71 241.0 0.1 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family UPF0029 PF01205.19 CAM44271.1 - 9.5e-29 99.8 0.0 1.6e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 CAM44271.1 - 0.016 15.5 0.8 0.14 12.5 0.8 2.2 1 1 0 1 1 1 0 RWD domain 2OG-FeII_Oxy_2 PF13532.6 CAM44272.2 - 3.1e-07 30.8 0.0 1.6e-06 28.4 0.0 2.2 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily START PF01852.19 CAM44273.1 - 2.8e-05 23.6 0.0 0.11 11.9 0.0 2.5 2 0 0 2 2 2 2 START domain DUF4187 PF13821.6 CAM44273.1 - 0.087 12.6 0.1 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) DnaJ PF00226.31 CAM44274.1 - 5e-06 26.5 0.0 1.1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain HTH_38 PF13936.6 CAM44274.1 - 0.004 16.9 0.0 0.011 15.5 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain PSP1 PF04468.12 CAM44275.1 - 0.045 14.0 0.0 0.08 13.2 0.0 1.4 1 0 0 1 1 1 0 PSP1 C-terminal conserved region Tubulin PF00091.25 CAM44276.1 - 0.0025 18.0 0.0 0.004 17.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain DUF4041 PF13250.6 CAM44277.2 - 0.091 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4041) Cep57_CLD_2 PF14197.6 CAM44279.2 - 0.0062 16.6 10.8 0.0062 16.6 10.8 10.5 4 3 8 13 13 13 2 Centrosome localisation domain of PPC89 MAP65_ASE1 PF03999.12 CAM44280.1 - 0.00045 19.1 16.9 0.0017 17.1 9.5 2.6 1 1 1 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) CLZ PF16526.5 CAM44280.1 - 0.0017 18.7 2.8 0.0017 18.7 2.8 4.1 4 1 1 5 5 5 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Herpes_BLRF2 PF05812.12 CAM44280.1 - 0.0049 17.0 0.0 0.0049 17.0 0.0 2.9 3 0 0 3 3 3 1 Herpesvirus BLRF2 protein DUF2451 PF10474.9 CAM44280.1 - 0.07 12.9 4.6 0.048 13.5 2.8 1.6 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2451) Tweety PF04906.13 CAM44280.1 - 0.086 11.5 10.7 1.9 7.0 4.2 3.3 3 1 0 3 3 3 0 Tweety Baculo_PEP_C PF04513.12 CAM44280.1 - 0.23 11.5 9.2 19 5.3 5.6 3.7 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus AIF-MLS PF14962.6 CAM44280.1 - 0.25 11.3 5.1 1.7 8.6 3.1 2.2 2 0 0 2 2 2 0 Mitochondria Localisation Sequence DUF2894 PF11445.8 CAM44280.1 - 0.43 11.0 13.1 0.093 13.2 8.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2894) HrpA_pilin PF09589.10 CAM44280.1 - 0.52 11.0 3.2 1.5 9.6 2.4 2.2 1 1 1 2 2 2 0 HrpA pilus formation protein DUF948 PF06103.11 CAM44280.1 - 0.54 10.6 10.8 0.21 11.8 2.1 3.7 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) TPR_MLP1_2 PF07926.12 CAM44280.1 - 0.69 10.0 28.7 0.94 9.5 3.5 3.5 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF16 PF01519.16 CAM44280.1 - 0.71 10.4 22.2 2.7 8.5 7.6 3.5 2 1 1 3 3 3 0 Protein of unknown function DUF16 FliD_C PF07195.12 CAM44280.1 - 1.6 8.1 10.8 0.51 9.7 2.1 2.7 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 C-terminus TBD PF12845.7 CAM44280.1 - 1.7 8.6 5.7 31 4.6 0.0 4.5 4 1 1 5 5 5 0 TBD domain Prominin PF05478.11 CAM44280.1 - 2.7 5.9 17.5 1.1 7.2 10.6 2.5 1 1 1 3 3 3 0 Prominin SPACA9 PF15120.6 CAM44280.1 - 2.8 7.7 15.5 0.13 12.0 8.8 2.1 2 1 1 3 3 3 0 Sperm acrosome-associated protein 9 DUF1043 PF06295.12 CAM44280.1 - 3.4 7.7 18.7 3.5 7.6 8.6 3.3 2 1 2 4 4 3 0 Protein of unknown function (DUF1043) DUF2935 PF11155.8 CAM44280.1 - 3.4 8.0 6.6 5.1 7.4 3.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) Fib_alpha PF08702.10 CAM44280.1 - 5.3 7.2 23.4 2 8.6 8.5 3.5 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family GP41 PF00517.17 CAM44280.1 - 8.7 6.2 10.9 0.17 11.8 1.6 2.5 2 1 1 3 3 3 0 Retroviral envelope protein Hexapep PF00132.24 CAM44281.1 - 1.7e-07 30.7 12.2 0.061 13.1 0.2 5.3 3 2 3 6 6 6 5 Bacterial transferase hexapeptide (six repeats) NOB1_Zn_bind PF08772.11 CAM44283.1 - 2e-25 88.7 0.1 3.8e-25 87.8 0.1 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 CAM44283.1 - 5.3e-22 78.1 0.2 1.2e-21 77.0 0.2 1.7 1 0 0 1 1 1 1 PIN domain of ribonuclease DUF35_N PF12172.8 CAM44283.1 - 0.00091 19.1 0.8 0.0019 18.0 0.8 1.4 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) DZR PF12773.7 CAM44283.1 - 0.011 15.8 0.3 0.019 15.0 0.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-NADH-PPase PF09297.11 CAM44283.1 - 9.4 6.0 6.5 23 4.7 1.5 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain CRISPR_Cse2 PF09485.10 CAM44285.1 - 1.2 9.7 3.9 2.3 8.7 0.3 2.8 2 2 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) CK_II_beta PF01214.18 CAM44286.1 - 7.9e-74 247.4 0.0 1e-73 247.1 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit API5 PF05918.11 CAM44287.1 - 3.2 6.5 16.3 7.3 5.3 16.3 1.6 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF4518 PF15008.6 CAM44287.1 - 5.6 6.1 6.4 14 4.8 6.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) HU-CCDC81_euk_2 PF18289.1 CAM44288.1 - 1.7e-16 60.1 0.0 4.5e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 HU-CCDC81_euk_1 PF14908.6 CAM44288.1 - 6.1e-14 51.9 0.2 9.3e-14 51.4 0.2 1.3 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 Ribosomal_S2 PF00318.20 CAM44289.1 - 6.9e-29 100.6 0.5 6e-17 61.6 0.2 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 CAM44289.1 - 0.0045 18.3 2.3 0.0082 17.5 2.3 1.4 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Sulfotransfer_1 PF00685.27 CAM44289.1 - 0.017 14.6 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase domain Porin_3 PF01459.22 CAM44290.1 - 1.9e-05 24.2 0.1 0.36 10.3 0.0 2.9 2 1 0 2 2 2 2 Eukaryotic porin zinc_ribbon_5 PF13719.6 CAM44290.1 - 0.073 12.8 0.2 0.16 11.8 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zf-C2H2 PF00096.26 CAM44290.1 - 0.54 10.8 3.2 0.5 10.9 1.1 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type VHS PF00790.19 CAM44291.1 - 7.3e-09 35.6 0.0 1.7e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 VHS domain Kinesin PF00225.23 CAM44292.1 - 1.5e-24 86.6 10.4 9.2e-19 67.5 0.0 3.5 3 1 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 CAM44292.1 - 1e-06 28.8 0.0 1e-06 28.8 0.0 3.1 3 1 0 3 3 3 1 Microtubule binding PTAC PF06130.12 CAM44292.1 - 0.16 12.2 1.0 0.47 10.6 1.0 1.9 1 0 0 1 1 1 0 Phosphate propanoyltransferase PIN_9 PF18477.1 CAM44292.1 - 7.9 6.8 12.6 0.38 11.1 2.8 2.9 1 1 1 2 2 2 0 PIN like domain Cob_adeno_trans PF01923.18 CAM44292.1 - 9.8 6.3 14.0 0.11 12.7 0.4 2.9 3 1 0 3 3 3 0 Cobalamin adenosyltransferase MA3 PF02847.17 CAM44293.1 - 1e-12 48.0 2.2 1.3e-12 47.7 0.4 2.0 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 CAM44293.1 - 1.5e-05 24.7 2.4 3e-05 23.8 0.3 2.3 2 1 0 2 2 2 1 MIF4G domain VPS28 PF03997.12 CAM44294.1 - 1.6e-44 151.9 0.1 1.8e-44 151.7 0.1 1.0 1 0 0 1 1 1 1 VPS28 protein Aldedh PF00171.22 CAM44295.1 - 3.8e-127 424.6 0.7 4.3e-127 424.4 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SNF2_N PF00176.23 CAM44296.1 - 6.8e-62 209.2 0.0 1.2e-61 208.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CAM44296.1 - 1.9e-18 66.8 0.0 6.1e-18 65.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAM44296.1 - 5.7e-09 36.2 0.0 1.2e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CAM44296.1 - 0.00016 21.5 0.0 0.00033 20.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 CAM44296.1 - 0.0054 16.0 1.8 0.023 13.9 0.0 2.6 3 0 0 3 3 3 1 ERCC3/RAD25/XPB C-terminal helicase Sec8_exocyst PF04048.14 CAM44296.1 - 0.061 13.2 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain PQQ_3 PF13570.6 CAM44298.2 - 1.1 9.8 4.5 4.4 7.9 0.2 4.3 4 0 0 4 4 4 0 PQQ-like domain NDUF_B12 PF08122.12 CAM44300.2 - 0.096 12.8 4.2 2.1 8.4 0.4 3.2 3 1 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family Glyco_hydro_65m PF03632.15 CAM44301.1 - 2.9e-68 230.5 0.0 5e-68 229.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.15 CAM44301.1 - 2.1e-25 89.7 0.4 4.3e-25 88.7 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.15 CAM44301.1 - 4.1e-06 26.6 0.0 9.5e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain HAD_2 PF13419.6 CAM44301.1 - 0.00058 20.0 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF2968 PF11180.8 CAM44303.1 - 0.016 14.8 178.8 0.16 11.6 7.7 12.6 5 2 9 14 14 14 0 Protein of unknown function (DUF2968) Cep57_CLD PF14073.6 CAM44303.1 - 0.057 13.4 121.5 0.053 13.5 0.8 13.2 9 3 2 13 13 13 0 Centrosome localisation domain of Cep57 FlaC_arch PF05377.11 CAM44303.1 - 2.4 8.6 56.0 19 5.7 0.7 12.5 13 0 0 13 13 13 0 Flagella accessory protein C (FlaC) HEAT PF02985.22 CAM44306.2 - 4.5 7.8 13.3 24 5.6 0.0 6.9 6 1 1 7 7 7 0 HEAT repeat Cnl2_NKP2 PF09447.10 CAM44307.1 - 0.15 12.2 4.0 1.5 9.0 0.4 2.8 3 0 0 3 3 3 0 Cnl2/NKP2 family protein DUF737 PF05300.11 CAM44307.1 - 0.23 11.8 10.9 0.38 11.1 10.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) GST_C_2 PF13410.6 CAM44310.1 - 2.6e-07 30.6 0.0 1e-06 28.7 0.0 2.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CAM44310.1 - 0.00035 20.7 0.0 0.00073 19.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF4986 PF16375.5 CAM44312.1 - 0.41 11.4 2.4 9.5 7.0 0.2 3.9 2 0 0 2 2 2 0 Domain of unknown function Pcc1 PF09341.10 CAM44312.1 - 1.8 8.8 8.9 0.57 10.4 1.3 3.9 3 1 1 4 4 4 0 Transcription factor Pcc1 DUF244 PF03112.14 CAM44312.1 - 3.2 7.6 7.2 11 5.8 0.4 3.0 2 1 1 3 3 3 0 Uncharacterized protein family (ORF7) DUF Pkinase PF00069.25 CAM44313.1 - 4.4e-57 193.4 0.0 7.4e-57 192.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM44313.1 - 1.5e-35 122.7 0.2 3e-35 121.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM44313.1 - 8.2e-10 38.5 0.1 9.7e-08 31.7 0.0 2.6 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 CAM44313.1 - 0.00016 21.7 0.0 0.12 12.3 0.0 3.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family C1_2 PF03107.16 CAM44313.1 - 0.0014 18.9 3.8 0.0014 18.9 3.8 2.1 2 0 0 2 2 2 1 C1 domain Kdo PF06293.14 CAM44313.1 - 0.0042 16.4 0.0 0.0089 15.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 CAM44313.1 - 0.026 13.6 0.0 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 FYVE_2 PF02318.16 CAM44313.1 - 0.071 13.3 4.9 0.19 12.0 4.9 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger zf-piccolo PF05715.13 CAM44313.1 - 0.14 12.3 4.9 0.31 11.2 4.9 1.6 1 0 0 1 1 1 0 Piccolo Zn-finger zf-UDP PF14569.6 CAM44313.1 - 4.4 7.5 7.6 8.3 6.6 6.1 2.1 2 0 0 2 2 2 0 Zinc-binding RING-finger zf_C2H2_ZHX PF18387.1 CAM44313.1 - 5.8 6.6 5.8 1.9 8.2 0.0 2.8 2 1 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Ubie_methyltran PF01209.18 CAM44314.1 - 3.9e-107 356.9 0.0 4.5e-107 356.7 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 CAM44314.1 - 3.5e-16 59.7 0.1 1.5e-15 57.7 0.1 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAM44314.1 - 5.3e-16 59.0 0.0 1e-15 58.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAM44314.1 - 1.4e-09 37.9 0.0 2.2e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAM44314.1 - 2.9e-07 31.2 0.0 4.5e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAM44314.1 - 4.5e-05 23.3 0.0 7.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 CAM44314.1 - 0.00028 20.8 0.0 0.022 14.6 0.0 2.6 2 1 1 3 3 3 1 Hypothetical methyltransferase WD40 PF00400.32 CAM44315.1 - 0.067 14.1 3.3 2.3 9.2 0.0 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat Y_phosphatase PF00102.27 CAM44316.1 - 6.7e-63 212.4 0.0 9.9e-63 211.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CAM44316.1 - 0.00044 20.3 0.0 0.001 19.1 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 CAM44316.1 - 0.00054 19.8 1.5 0.0013 18.6 0.0 2.3 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CAM44316.1 - 0.018 15.1 0.0 0.049 13.8 0.0 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate Pyr_redox_2 PF07992.14 CAM44317.1 - 2e-53 181.5 0.0 2.5e-53 181.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CAM44317.1 - 6.3e-13 49.1 0.0 1.4e-08 35.1 0.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CAM44317.1 - 7.4e-06 26.1 0.0 0.2 11.9 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CAM44317.1 - 3.4e-05 23.1 0.0 0.024 13.7 0.0 2.7 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 CAM44317.1 - 0.00024 20.8 0.2 0.58 9.7 0.0 3.1 2 1 1 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.22 CAM44317.1 - 0.002 17.3 0.0 1 8.3 0.0 3.1 3 0 0 3 3 3 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 CAM44317.1 - 0.0098 15.0 0.1 3.6 6.5 0.0 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 CAM44317.1 - 0.026 13.8 0.0 3.3 6.9 0.0 3.1 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 CAM44317.1 - 0.041 12.7 0.0 12 4.6 0.0 2.9 2 1 0 3 3 3 0 Tryptophan halogenase NAD_binding_7 PF13241.6 CAM44317.1 - 0.085 13.3 0.7 4.8 7.7 0.0 3.3 3 1 0 3 3 3 0 Putative NAD(P)-binding Pribosyltran_N PF13793.6 CAM44318.1 - 9.9e-40 135.1 0.2 3e-39 133.6 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CAM44318.1 - 1.3e-30 106.8 1.5 2.6e-30 105.8 0.8 1.8 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CAM44318.1 - 3.9e-16 59.0 0.2 9.3e-16 57.7 0.2 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CAM44318.1 - 0.00043 19.8 0.1 0.001 18.6 0.1 1.6 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase IL2 PF00715.17 CAM44318.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Interleukin 2 BCS1_N PF08740.11 CAM44319.1 - 9.4e-30 104.0 1.2 1.6e-29 103.3 1.2 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 CAM44319.1 - 1.4e-11 45.0 0.0 8.4e-06 26.2 0.0 2.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CAM44319.1 - 0.00049 20.5 0.7 0.0023 18.4 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CAM44319.1 - 0.0012 18.6 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CAM44319.1 - 0.0022 18.0 0.0 0.0048 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 CAM44319.1 - 0.012 15.5 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CAM44319.1 - 0.012 15.8 0.0 0.012 15.8 0.0 2.3 2 0 0 2 2 1 0 AAA domain TIP49 PF06068.13 CAM44319.1 - 0.031 13.5 0.0 0.053 12.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_3 PF07726.11 CAM44319.1 - 0.066 13.1 0.0 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CAM44319.1 - 0.089 13.3 0.0 0.3 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 CAM44319.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_6 PF12774.7 CAM44319.1 - 0.18 10.8 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AIRS_C PF02769.22 CAM44320.1 - 6e-19 68.7 0.0 1.4e-18 67.5 0.0 1.6 1 1 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 CAM44320.1 - 1.9e-09 38.0 0.3 5.4e-09 36.6 0.3 1.7 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Extensin-like_C PF06904.12 CAM44320.1 - 0.037 14.1 0.0 0.07 13.2 0.0 1.4 1 0 0 1 1 1 0 Extensin-like protein C-terminus SF1-HH PF16275.5 CAM44321.1 - 7.5e-07 29.5 0.1 1.8e-06 28.3 0.1 1.7 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 CAM44321.1 - 9e-06 25.4 0.0 1.9e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 KH domain TylF PF05711.11 CAM44322.1 - 1e-18 67.6 0.0 5.3e-18 65.2 0.0 2.0 1 1 0 1 1 1 1 Macrocin-O-methyltransferase (TylF) Methyltransf_24 PF13578.6 CAM44322.1 - 7.6e-07 30.1 0.1 3.6e-06 28.0 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain CmcI PF04989.12 CAM44322.1 - 0.0079 15.9 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Cephalosporin hydroxylase S-layer PF07752.11 CAM44322.1 - 0.19 10.7 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 S-layer protein SEP PF08059.13 CAM44323.2 - 8.1e-09 35.9 0.0 2.2e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 CAM44323.2 - 0.00019 21.5 0.0 0.00042 20.5 0.0 1.6 1 0 0 1 1 1 1 UBX domain ATG16 PF08614.11 CAM44323.2 - 0.00084 19.6 5.2 0.0019 18.4 5.2 1.6 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) OmpH PF03938.14 CAM44323.2 - 0.014 15.8 3.7 0.029 14.7 3.7 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FPP PF05911.11 CAM44323.2 - 0.024 12.9 5.8 0.036 12.3 5.8 1.2 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil IFT57 PF10498.9 CAM44323.2 - 0.036 13.0 1.7 0.056 12.4 1.7 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF4407 PF14362.6 CAM44323.2 - 0.037 13.4 4.4 0.074 12.4 4.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) tRNA-synt_1d PF00750.19 CAM44323.2 - 0.044 12.7 2.0 0.069 12.1 2.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (R) Jnk-SapK_ap_N PF09744.9 CAM44323.2 - 0.054 13.7 8.3 0.099 12.9 8.3 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Spc24 PF08286.11 CAM44323.2 - 0.14 12.4 5.6 0.3 11.4 5.6 1.6 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 TRPM_tetra PF16519.5 CAM44323.2 - 0.14 12.3 0.1 0.32 11.1 0.1 1.5 1 0 0 1 1 1 0 Tetramerisation domain of TRPM Ax_dynein_light PF10211.9 CAM44323.2 - 0.49 10.3 5.3 1 9.3 5.3 1.5 1 0 0 1 1 1 0 Axonemal dynein light chain V_ATPase_I PF01496.19 CAM44323.2 - 0.64 7.9 2.7 0.99 7.2 2.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cep57_MT_bd PF06657.13 CAM44323.2 - 0.76 10.3 5.9 1.7 9.2 5.9 1.6 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 APG6_N PF17675.1 CAM44323.2 - 2.1 8.9 14.6 1.7 9.2 12.8 1.7 2 0 0 2 2 2 0 Apg6 coiled-coil region DAO PF01266.24 CAM44325.1 - 3.5e-44 151.8 0.0 4.3e-44 151.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CAM44325.1 - 0.00021 21.5 0.2 0.00051 20.2 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CAM44325.1 - 0.0012 18.1 0.0 0.0039 16.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CAM44325.1 - 0.0015 17.9 0.2 0.005 16.1 0.0 1.9 2 0 0 2 2 2 1 Thi4 family Mqo PF06039.15 CAM44325.1 - 0.002 16.8 0.0 0.022 13.3 0.0 2.1 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) TrkA_N PF02254.18 CAM44325.1 - 0.0086 16.3 0.2 0.019 15.2 0.2 1.6 1 0 0 1 1 1 1 TrkA-N domain FAD_binding_3 PF01494.19 CAM44325.1 - 0.016 14.5 0.6 0.14 11.4 0.2 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 CAM44325.1 - 0.06 13.9 0.2 0.21 12.2 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CAM44325.1 - 0.12 11.4 0.1 0.19 10.7 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Phage_TAC_13 PF16459.5 CAM44326.1 - 0.17 12.3 0.1 0.46 11.0 0.1 1.7 1 0 0 1 1 1 0 Phage tail assembly chaperone, TAC HlyIII PF03006.20 CAM44327.1 - 5.7e-26 91.6 9.5 7.3e-26 91.3 9.5 1.1 1 0 0 1 1 1 1 Haemolysin-III related HlyIII PF03006.20 CAM44328.2 - 7.5e-52 176.3 27.0 9.3e-52 176.0 27.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF4402 PF14352.6 CAM44329.1 - 0.023 15.3 1.5 0.078 13.6 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4402) HlyIII PF03006.20 CAM44331.1 - 7.4e-51 173.0 26.1 9.4e-51 172.7 26.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.11 CAM44331.1 - 0.022 14.8 0.9 0.16 12.1 0.8 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF962) HlyIII PF03006.20 CAM44332.1 - 2.1e-53 181.3 27.8 2.6e-53 181.1 27.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related TMEM238 PF15125.6 CAM44332.1 - 0.038 14.2 0.6 0.038 14.2 0.6 2.9 3 2 1 4 4 4 0 TMEM238 protein family PCIF1_WW PF12237.8 CAM44333.1 - 2.1e-28 99.1 0.3 2.4e-18 66.3 0.2 2.3 2 0 0 2 2 2 2 Phosphorylated CTD interacting factor 1 WW domain AAA_16 PF13191.6 CAM44334.1 - 0.033 14.6 0.0 0.033 14.6 0.0 2.8 2 1 1 3 3 3 0 AAA ATPase domain AAA_29 PF13555.6 CAM44334.1 - 0.11 12.3 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain KTI12 PF08433.10 CAM44334.1 - 0.12 11.8 0.2 1.4 8.3 0.0 2.4 3 0 0 3 3 3 0 Chromatin associated protein KTI12 AAA_33 PF13671.6 CAM44334.1 - 0.14 12.4 5.6 0.26 11.5 1.1 3.3 1 1 1 2 2 2 0 AAA domain PAP_RNA-bind PF04926.15 CAM44335.1 - 0.038 13.6 0.0 0.081 12.5 0.0 1.5 1 0 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain Peptidase_M24 PF00557.24 CAM44336.2 - 1.9e-35 122.5 0.1 3.1e-35 121.8 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CAM44336.2 - 3.9e-10 39.5 0.0 8.9e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain EMP24_GP25L PF01105.24 CAM44337.1 - 1.4e-12 47.9 0.0 1.7e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD HA PF03457.14 CAM44338.1 - 0.076 13.4 0.1 0.22 11.9 0.0 1.8 2 0 0 2 2 2 0 Helicase associated domain HrpB2 PF09487.10 CAM44338.1 - 0.079 13.4 0.1 0.26 11.7 0.0 1.9 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB2) Transcript_VP30 PF11507.8 CAM44338.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Ebola virus-specific transcription factor VP30 CAP_C PF08603.11 CAM44339.1 - 1.5e-46 157.9 3.3 1.9e-46 157.6 3.3 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal CAP_N PF01213.19 CAM44339.1 - 2.3e-15 56.9 2.3 3.5e-15 56.3 2.3 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal TBCC PF07986.12 CAM44339.1 - 2.5e-05 24.0 7.2 4e-05 23.3 7.2 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C RskA PF10099.9 CAM44339.1 - 0.02 15.2 0.9 0.029 14.7 0.9 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA NERD PF08378.11 CAM44342.1 - 9.6e-17 61.4 0.3 3e-16 59.8 0.3 1.8 1 1 0 1 1 1 1 Nuclease-related domain DUF3025 PF11227.8 CAM44342.1 - 0.14 11.9 1.9 0.43 10.4 1.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3025) tRNA-synt_1 PF00133.22 CAM44343.1 - 2.5e-213 709.7 2.4 9.9e-213 707.7 0.1 2.6 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CAM44343.1 - 4.8e-21 75.3 0.0 1.6e-20 73.6 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CAM44343.1 - 1.9e-13 50.0 2.3 0.00023 20.0 0.2 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 CAM44343.1 - 0.0014 18.1 0.6 0.068 12.5 0.0 3.0 2 1 1 3 3 3 1 tRNA synthetases class I (C) catalytic domain GAT PF03127.14 CAM44343.1 - 0.17 12.2 0.4 0.4 11.0 0.4 1.6 1 0 0 1 1 1 0 GAT domain Gamma_PGA_hydro PF05908.11 CAM44344.1 - 0.14 11.6 0.4 0.31 10.4 0.2 1.5 1 1 1 2 2 2 0 Poly-gamma-glutamate hydrolase Cyclin_N PF00134.23 CAM44345.1 - 0.00023 20.9 0.1 0.0021 17.8 0.0 2.3 2 1 0 2 2 2 1 Cyclin, N-terminal domain E1_UFD PF09358.10 CAM44346.2 - 0.041 14.6 0.0 1.9 9.2 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin fold domain SUKH-4 PF14435.6 CAM44346.2 - 0.083 12.9 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 SUKH-4 immunity protein DAO PF01266.24 CAM44347.1 - 2.4e-17 63.6 5.7 1.5e-07 31.3 0.5 3.7 4 0 0 4 4 4 3 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CAM44347.1 - 1.4e-07 31.6 0.3 4.4e-07 30.0 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CAM44347.1 - 2.9e-06 26.8 0.1 5e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CAM44347.1 - 1.3e-05 25.6 1.3 2.5e-05 24.8 0.5 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CAM44347.1 - 0.00051 19.2 0.3 0.001 18.2 0.2 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 CAM44347.1 - 0.00086 18.6 0.1 0.0018 17.6 0.1 1.4 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 CAM44347.1 - 0.0069 15.7 0.4 0.013 14.8 0.4 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 CAM44347.1 - 0.0074 15.4 1.4 0.012 14.8 1.4 1.3 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.18 CAM44347.1 - 0.013 15.4 0.3 0.026 14.4 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 CAM44347.1 - 0.024 13.4 0.4 0.036 12.8 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 CAM44347.1 - 0.04 13.2 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CAM44347.1 - 0.046 13.0 0.5 0.092 12.0 0.5 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 CAM44347.1 - 0.056 13.4 0.3 0.12 12.4 0.3 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 CAM44347.1 - 0.11 11.8 1.0 0.16 11.2 0.0 1.8 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_2 PF03446.15 CAM44347.1 - 0.2 11.8 0.1 0.41 10.8 0.1 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase IlvB_leader PF08049.11 CAM44347.1 - 2.5 8.1 4.1 1.6 8.7 0.2 2.6 3 0 0 3 3 2 0 IlvB leader peptide OB_NTP_bind PF07717.16 CAM44348.1 - 3e-15 56.4 0.0 6e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 CAM44348.1 - 4.2e-14 52.7 1.4 1.2e-13 51.2 1.4 1.9 1 1 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CAM44348.1 - 3.4e-13 49.9 0.0 1.2e-12 48.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CAM44348.1 - 4.5e-09 36.3 0.0 8.3e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CAM44348.1 - 8.1e-05 22.9 0.1 0.00037 20.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CAM44348.1 - 0.0059 16.9 0.8 0.026 14.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain PhoH PF02562.16 CAM44348.1 - 0.0097 15.4 0.1 0.058 12.9 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein ResIII PF04851.15 CAM44348.1 - 0.011 15.8 0.0 4 7.4 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 CAM44348.1 - 0.011 14.8 0.1 0.088 11.9 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein ATPase PF06745.13 CAM44348.1 - 0.035 13.5 0.0 0.075 12.4 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 CAM44348.1 - 0.04 13.4 0.0 0.082 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Kringle PF00051.18 CAM44348.1 - 0.042 14.2 0.1 0.088 13.1 0.1 1.4 1 0 0 1 1 1 0 Kringle domain AAA_30 PF13604.6 CAM44348.1 - 0.046 13.4 0.0 0.098 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CAM44348.1 - 0.12 12.9 0.0 0.28 11.7 0.0 1.6 1 0 0 1 1 1 0 ABC transporter CK2S PF15011.6 CAM44348.1 - 0.13 12.2 0.1 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 Casein Kinase 2 substrate Sigma54_activat PF00158.26 CAM44348.1 - 0.15 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.6 CAM44348.1 - 0.19 11.5 0.0 0.45 10.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain CUE PF02845.16 CAM44351.1 - 0.0025 17.5 0.0 0.19 11.4 0.0 2.7 2 0 0 2 2 2 2 CUE domain Cullin_binding PF03556.15 CAM44352.1 - 2.1e-20 73.4 1.4 4.5e-20 72.3 1.4 1.5 1 0 0 1 1 1 1 Cullin binding DUF2992 PF11208.8 CAM44355.1 - 6.6 7.0 6.3 10 6.4 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) TruD PF01142.18 CAM44356.1 - 5.7e-61 206.6 0.0 4e-54 184.0 0.0 2.7 3 0 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) RAB3GAP2_N PF14655.6 CAM44357.1 - 9.8e-12 44.8 0.0 1.6e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus MS_channel PF00924.18 CAM44358.2 - 1.7e-17 63.7 0.6 2e-17 63.4 0.6 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel Gcd10p PF04189.13 CAM44359.2 - 9.8e-47 159.5 0.1 1.4e-46 159.0 0.1 1.2 1 0 0 1 1 1 1 Gcd10p family LRR_4 PF12799.7 CAM44360.2 - 4.6e-08 33.2 0.4 0.089 13.3 0.1 3.3 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM44360.2 - 8.8e-05 22.2 1.0 0.0047 16.7 0.0 2.9 2 1 2 4 4 4 2 Leucine rich repeat LRR_9 PF14580.6 CAM44360.2 - 0.0001 21.9 0.1 0.0004 19.9 0.1 2.1 1 1 0 1 1 1 1 Leucine-rich repeat FlbT PF07378.11 CAM44361.2 - 0.13 12.4 0.3 2.7 8.1 0.2 2.9 3 0 0 3 3 3 0 Flagellar protein FlbT DUF945 PF06097.11 CAM44362.1 - 0.026 13.7 0.5 0.042 13.0 0.5 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) Nitroreductase PF00881.24 CAM44364.1 - 1.1e-13 51.6 0.2 1.3e-13 51.3 0.2 1.1 1 0 0 1 1 1 1 Nitroreductase family HMG_box PF00505.19 CAM44365.1 - 0.37 11.3 3.2 0.64 10.5 0.1 2.9 3 1 0 3 3 3 0 HMG (high mobility group) box Phage_TAC_7 PF10109.9 CAM44365.1 - 0.73 10.0 4.0 1 9.5 0.5 2.7 2 1 0 2 2 2 0 Phage tail assembly chaperone proteins, E, or 41 or 14 DUF3106 PF11304.8 CAM44365.1 - 1.1 9.7 10.3 0.87 10.1 0.5 3.4 2 1 0 3 3 3 0 Protein of unknown function (DUF3106) HMG_box_2 PF09011.10 CAM44366.1 - 0.00014 22.3 4.3 0.0073 16.9 0.6 2.5 1 1 1 2 2 2 2 HMG-box domain YABBY PF04690.13 CAM44366.1 - 0.00019 22.0 1.9 0.00023 21.8 1.9 1.1 1 0 0 1 1 1 1 YABBY protein DUF3106 PF11304.8 CAM44366.1 - 0.02 15.4 0.9 0.032 14.7 0.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3106) HMG_box PF00505.19 CAM44366.1 - 0.033 14.6 4.5 0.069 13.6 0.2 2.9 2 2 0 2 2 2 0 HMG (high mobility group) box HMG_box_2 PF09011.10 CAM44367.1 - 0.0039 17.8 0.0 0.0045 17.5 0.0 1.1 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 CAM44367.1 - 0.011 16.2 0.2 0.017 15.5 0.2 1.3 1 1 0 1 1 1 0 HMG (high mobility group) box Gtr1_RagA PF04670.12 CAM44371.1 - 2.7e-67 226.5 0.1 3.5e-67 226.2 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CAM44371.1 - 7.2e-07 29.3 0.0 1.5e-06 28.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 CAM44371.1 - 7.2e-06 25.6 0.0 1.4e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CAM44371.1 - 1.9e-05 24.9 0.0 4.5e-05 23.6 0.0 1.8 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CAM44371.1 - 0.012 15.3 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Ras family YliH PF10799.8 CAM44371.1 - 0.012 15.5 0.6 0.029 14.3 0.0 2.0 2 0 0 2 2 2 0 Biofilm formation protein (YliH/bssR) SRPRB PF09439.10 CAM44371.1 - 0.026 14.0 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Pro-rich_19 PF15455.6 CAM44371.1 - 0.07 12.3 0.0 0.099 11.8 0.0 1.1 1 0 0 1 1 1 0 Proline-rich 19 DUF910 PF06014.11 CAM44371.1 - 0.097 12.7 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF910) CDP-OH_P_transf PF01066.21 CAM44373.1 - 9.4e-16 58.3 0.1 9.4e-16 58.3 0.1 3.8 3 1 0 3 3 3 2 CDP-alcohol phosphatidyltransferase Taxilin PF09728.9 CAM44376.1 - 0.0032 16.7 48.0 0.0043 16.3 48.0 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein DUF4200 PF13863.6 CAM44376.1 - 0.017 15.5 5.7 0.017 15.5 5.7 3.7 1 1 3 4 4 4 0 Domain of unknown function (DUF4200) Baculo_F PF12259.8 CAM44376.1 - 1.6 7.1 15.2 0.26 9.8 10.6 1.8 1 1 1 2 2 2 0 Baculovirus F protein LmjF365940-deam PF14421.6 CAM44377.1 - 1.5e-40 138.9 0.0 5.3e-21 75.1 0.0 2.3 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases DUF5567 PF17722.1 CAM44379.1 - 0.014 15.3 0.7 6.4 6.6 0.1 2.7 2 1 0 3 3 3 0 Family of unknown function (DUF5567) DUF4996 PF16387.5 CAM44380.1 - 8.6e-32 109.7 0.2 1.8e-31 108.7 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function GDPD PF03009.17 CAM44380.1 - 2e-23 83.4 0.2 3.8e-23 82.5 0.1 1.4 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family PI-PLC-X PF00388.19 CAM44380.1 - 0.009 15.6 0.2 0.019 14.5 0.2 1.8 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain FAS_meander PF17951.1 CAM44380.1 - 0.054 13.3 0.0 0.09 12.6 0.0 1.3 1 0 0 1 1 1 0 Fatty acid synthase meander beta sheet domain Tmemb_185A PF10269.9 CAM44381.1 - 9e-07 28.8 14.3 0.0013 18.4 0.4 2.2 2 0 0 2 2 2 2 Transmembrane Fragile-X-F protein RRM_1 PF00076.22 CAM44382.2 - 0.0036 17.1 0.0 0.008 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SpoV PF08183.11 CAM44383.1 - 1.5e-12 47.2 0.2 2.4e-12 46.6 0.2 1.3 1 0 0 1 1 1 1 Stage V sporulation protein family AbiH PF14253.6 CAM44384.2 - 0.46 10.3 0.9 1.1 9.0 0.9 1.6 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH Arabino_trans_N PF17689.1 CAM44385.1 - 0.027 14.6 0.4 0.027 14.6 0.4 2.1 2 0 0 2 2 2 0 Arabinosyltransferase concanavalin like domain Filament PF00038.21 CAM44385.1 - 0.87 9.1 27.4 0.43 10.1 6.4 3.0 1 1 0 2 2 2 0 Intermediate filament protein CorA PF01544.18 CAM44385.1 - 8.2 5.6 13.0 1.3 8.3 8.2 1.9 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein OTU PF02338.19 CAM44386.2 - 0.0013 19.3 0.0 0.0085 16.6 0.0 2.1 2 0 0 2 2 2 1 OTU-like cysteine protease DUF4223 PF13978.6 CAM44386.2 - 0.071 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4223) FAP206 PF12018.8 CAM44387.2 - 2.1e-12 47.2 0.1 0.0013 18.3 0.0 5.0 4 0 0 4 4 4 2 Domain of unknown function AAA_17 PF13207.6 CAM44387.2 - 2.9e-05 24.5 0.0 0.33 11.4 0.0 3.7 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CAM44387.2 - 0.00015 22.3 0.0 0.043 14.4 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CAM44387.2 - 0.00031 21.2 8.1 0.0022 18.4 0.0 4.8 4 0 0 4 4 4 1 AAA ATPase domain AAA_33 PF13671.6 CAM44387.2 - 0.0053 16.9 0.0 0.0053 16.9 0.0 3.9 3 1 1 4 4 3 1 AAA domain YHS PF04945.13 CAM44387.2 - 0.012 15.7 6.0 0.39 10.8 0.7 3.6 3 0 0 3 3 3 0 YHS domain HTH_1 PF00126.27 CAM44387.2 - 0.053 13.5 0.0 22 5.1 0.0 3.0 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family AAA_5 PF07728.14 CAM44387.2 - 0.11 12.5 0.0 0.48 10.4 0.0 2.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 CAM44387.2 - 0.13 12.6 0.0 1.6 9.2 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CAM44387.2 - 0.15 11.7 0.0 1.7 8.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 CAM44387.2 - 0.16 12.2 0.0 1.2 9.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zn_ribbon_2 PF12674.7 CAM44387.2 - 0.18 12.5 1.5 0.81 10.4 1.5 2.2 1 0 0 1 1 1 0 Putative zinc ribbon domain Astro_capsid_p PF12226.8 CAM44387.2 - 2.7 7.0 8.2 9.7 5.2 8.2 1.9 1 0 0 1 1 1 0 Turkey astrovirus capsid protein COG2 PF06148.11 CAM44388.1 - 5.3e-40 136.6 0.0 1.7e-39 134.9 0.0 2.0 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.8 CAM44388.1 - 2.7e-30 105.3 0.7 5.7e-29 101.1 0.1 2.8 1 1 1 2 2 2 1 Domain of unknown function (DUF3510) DARPP-32 PF05395.12 CAM44388.1 - 0.08 13.2 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 DUF5576 PF17739.1 CAM44388.1 - 0.93 9.6 2.9 1.9 8.6 0.1 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5576) MIF4G PF02854.19 CAM44390.1 - 1.4e-21 77.1 0.1 2.3e-21 76.4 0.1 1.4 1 0 0 1 1 1 1 MIF4G domain RabGAP-TBC PF00566.18 CAM44391.1 - 1e-58 198.6 0.1 1.4e-58 198.1 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RabGAP-TBC PF00566.18 CAM44392.1 - 4.9e-60 202.8 0.2 6.5e-60 202.4 0.2 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ABC1 PF03109.16 CAM44393.1 - 3.7e-28 98.1 0.0 9.1e-28 96.8 0.0 1.7 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 CAM44393.1 - 4.4e-07 29.5 0.0 0.0019 17.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM44393.1 - 4.5e-06 26.1 0.0 0.0078 15.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CAM44393.1 - 6.6e-05 22.9 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CAM44393.1 - 0.00052 19.7 0.0 0.00097 18.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 CAM44393.1 - 0.096 12.0 0.1 0.15 11.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5616 PF18481.1 CAM44393.1 - 0.1 12.9 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5616) Pkinase_fungal PF17667.1 CAM44393.1 - 0.12 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase TPR_14 PF13428.6 CAM44394.1 - 0.0005 20.7 6.0 3.1 8.9 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 CAM44394.1 - 0.0037 17.3 11.2 5.5 7.4 0.3 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 CAM44394.1 - 0.018 14.7 0.2 0.15 11.7 0.1 2.7 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) ANAPC3 PF12895.7 CAM44394.1 - 0.024 14.8 10.1 1.1 9.5 0.6 5.1 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 CAM44394.1 - 0.033 14.7 11.0 5.3 7.6 0.7 4.9 5 1 0 6 6 6 0 Tetratricopeptide repeat PPR PF01535.20 CAM44394.1 - 0.069 13.4 0.0 22 5.6 0.0 3.9 4 0 0 4 4 4 0 PPR repeat TPR_16 PF13432.6 CAM44394.1 - 0.34 11.6 14.6 4 8.2 0.2 5.3 5 1 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 CAM44394.1 - 0.53 11.1 6.4 23 6.0 0.6 4.5 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CAM44394.1 - 0.68 10.7 10.3 0.93 10.3 0.2 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 CAM44394.1 - 1.7 9.0 13.8 0.67 10.3 0.8 4.5 5 2 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 CAM44394.1 - 1.8 8.5 4.0 28 4.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat EF-hand_7 PF13499.6 CAM44395.1 - 3.6e-15 56.2 1.8 5.5e-07 30.0 0.0 2.4 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CAM44395.1 - 1.9e-09 36.4 1.6 0.001 18.4 0.0 4.6 4 1 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 CAM44395.1 - 2.4e-09 36.4 2.6 0.00013 21.6 0.0 4.2 4 1 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 CAM44395.1 - 3.7e-08 33.1 0.6 0.016 15.1 0.3 3.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 CAM44395.1 - 3.3e-05 24.1 0.1 0.0032 17.8 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 CAM44395.1 - 0.003 17.0 0.1 5.7 6.6 0.0 3.3 3 0 0 3 3 3 2 EF hand PheRS_DBD2 PF18554.1 CAM44395.1 - 0.22 11.6 1.8 3.9 7.6 0.1 3.0 3 0 0 3 3 3 0 PheRS DNA binding domain 2 ATP_bind_3 PF01171.20 CAM44396.1 - 3.1e-16 59.6 0.0 5.6e-16 58.8 0.0 1.4 1 1 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 CAM44396.1 - 1.8e-10 40.1 2.4 1.8e-10 40.1 2.4 4.4 5 0 0 5 5 5 1 Zinc-ribbon tRNA_Me_trans PF03054.16 CAM44396.1 - 0.013 14.3 0.0 0.028 13.2 0.0 1.5 1 1 0 1 1 1 0 tRNA methyl transferase PAPS_reduct PF01507.19 CAM44396.1 - 0.026 14.6 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family TF_Zn_Ribbon PF08271.12 CAM44396.1 - 0.064 12.8 2.2 0.18 11.3 0.1 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding zf-UBR PF02207.20 CAM44396.1 - 0.4 10.9 3.7 9 6.6 0.1 2.5 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) Rab5-bind PF09311.11 CAM44397.1 - 0.0015 18.0 1.6 0.0025 17.2 1.6 1.3 1 0 0 1 1 1 1 Rabaptin-like protein APG6_N PF17675.1 CAM44397.1 - 0.049 14.1 1.7 0.11 13.0 1.7 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region zf_C2H2_6 PF18450.1 CAM44397.1 - 0.19 11.5 0.2 0.42 10.4 0.2 1.6 1 0 0 1 1 1 0 Zinc Finger domain Fis1_TPR_C PF14853.6 CAM44399.1 - 1.6e-05 24.9 1.3 0.00013 22.0 1.1 2.2 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.28 CAM44399.1 - 0.027 14.3 0.1 0.052 13.4 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 CAM44399.1 - 0.075 13.2 0.2 0.22 11.7 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Sugar_tr PF00083.24 CAM44401.1 - 1.1e-97 327.8 39.1 1.6e-59 202.0 17.7 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CAM44401.1 - 8.8e-19 67.6 29.6 2.8e-16 59.4 28.8 2.4 3 0 0 3 3 3 2 Major Facilitator Superfamily YqhR PF11085.8 CAM44401.1 - 0.0095 15.9 2.1 0.0095 15.9 2.1 2.9 3 0 0 3 3 3 1 Conserved membrane protein YqhR Sugar_tr PF00083.24 CAM44402.1 - 4.5e-98 329.1 39.4 1.4e-59 202.2 17.7 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CAM44402.1 - 8.3e-20 71.0 29.9 1.3e-17 63.8 28.9 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily YqhR PF11085.8 CAM44402.1 - 0.0082 16.1 1.9 0.0082 16.1 1.9 2.9 3 0 0 3 3 3 1 Conserved membrane protein YqhR HlyE PF06109.13 CAM44402.1 - 0.12 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Haemolysin E (HlyE) Suc_Fer-like PF06999.12 CAM44403.1 - 5.5e-28 98.2 0.1 7.7e-28 97.7 0.1 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like LIDHydrolase PF10230.9 CAM44405.2 - 0.061 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Vps54 PF07928.12 CAM44406.1 - 2.5e-22 79.7 0.0 5.4e-21 75.4 0.0 3.0 2 1 0 2 2 2 1 Vps54-like protein GCN5L1 PF06320.13 CAM44406.1 - 0.0036 17.4 0.0 0.012 15.8 0.0 1.8 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) COG2 PF06148.11 CAM44406.1 - 0.073 13.2 0.1 0.25 11.4 0.0 1.9 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Tropomyosin_1 PF12718.7 CAM44407.1 - 6.2e-06 26.4 2.4 6.2e-06 26.4 2.4 3.1 4 0 0 4 4 4 1 Tropomyosin like CBFB_NFYA PF02045.15 CAM44407.1 - 0.19 12.3 2.0 0.66 10.6 2.0 1.9 1 0 0 1 1 1 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B AAA_13 PF13166.6 CAM44407.1 - 3.6 6.1 14.9 7 5.2 14.9 1.4 1 0 0 1 1 1 0 AAA domain DUF724 PF05266.14 CAM44407.1 - 5.1 6.9 14.1 9 6.1 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF724) Arf PF00025.21 CAM44408.1 - 6e-60 201.7 0.0 6.7e-60 201.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CAM44408.1 - 9.1e-13 48.5 0.0 1.2e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CAM44408.1 - 1e-11 44.7 0.0 1.2e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CAM44408.1 - 1.8e-11 43.9 0.0 1.1e-08 34.6 0.0 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CAM44408.1 - 7.4e-10 38.6 0.0 8.7e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CAM44408.1 - 3.2e-09 36.5 0.0 3.8e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CAM44408.1 - 3.6e-09 36.7 0.0 5.5e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CAM44408.1 - 0.0082 15.7 0.1 0.17 11.4 0.1 2.4 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 CAM44408.1 - 0.013 15.1 0.0 0.032 13.8 0.0 1.6 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CAM44408.1 - 0.017 15.2 0.0 2.4 8.2 0.0 2.1 2 0 0 2 2 2 0 Dynamin family TniB PF05621.11 CAM44408.1 - 0.07 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_28 PF13521.6 CAM44409.1 - 0.008 16.4 0.0 0.021 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain Ras PF00071.22 CAM44410.1 - 1e-45 155.2 0.3 1.4e-45 154.8 0.3 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAM44410.1 - 2.4e-30 105.2 0.1 5.4e-30 104.1 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAM44410.1 - 1.3e-07 31.2 0.0 1.8e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CAM44410.1 - 0.00032 20.7 0.0 0.001 19.1 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CAM44410.1 - 0.0077 15.8 0.1 1.7 8.2 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B TniB PF05621.11 CAM44410.1 - 0.011 15.1 0.0 0.043 13.2 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein Gtr1_RagA PF04670.12 CAM44410.1 - 0.028 13.8 0.2 0.082 12.3 0.0 1.8 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CAM44410.1 - 0.03 14.2 0.1 1.7 8.6 0.0 2.4 2 1 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 CAM44410.1 - 0.055 13.2 0.0 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 CAM44410.1 - 0.06 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DLIC PF05783.11 CAM44410.1 - 0.73 8.6 5.7 0.98 8.2 0.0 2.0 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) DnaJ_C PF01556.18 CAM44412.1 - 1e-36 126.2 0.0 1.5e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CAM44412.1 - 8e-27 93.2 6.9 1.4e-26 92.4 6.9 1.4 1 0 0 1 1 1 1 DnaJ domain Sugar_tr PF00083.24 CAM44413.2 - 8.4e-92 308.4 35.6 5.8e-60 203.4 17.3 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CAM44413.2 - 2.7e-17 62.7 31.0 2.4e-15 56.3 31.7 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily YqhR PF11085.8 CAM44413.2 - 0.0053 16.7 1.8 0.0053 16.7 1.8 2.6 3 0 0 3 3 3 1 Conserved membrane protein YqhR HlyE PF06109.13 CAM44413.2 - 0.098 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Haemolysin E (HlyE) S-methyl_trans PF02574.16 CAM44414.1 - 7.6e-70 235.8 0.1 8.9e-70 235.6 0.1 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Kelch_1 PF01344.25 CAM44414.1 - 0.0045 16.6 0.2 0.033 13.8 0.0 2.2 2 0 0 2 2 2 1 Kelch motif FliG_M PF14841.6 CAM44414.1 - 0.062 13.5 0.3 9.3 6.6 0.1 2.6 2 0 0 2 2 2 0 FliG middle domain Cullin_binding PF03556.15 CAM44414.1 - 0.13 12.7 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 Cullin binding IMPDH PF00478.25 CAM44414.1 - 0.18 10.7 0.1 0.29 10.1 0.1 1.4 1 1 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain PI3_PI4_kinase PF00454.27 CAM44415.2 - 3.2e-63 213.9 0.0 5.6e-63 213.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 CAM44415.2 - 6e-53 180.3 0.4 2.8e-52 178.1 0.2 2.2 2 0 0 2 2 2 1 FAT domain DUF3385 PF11865.8 CAM44415.2 - 3.4e-21 75.8 1.9 3.2e-19 69.4 0.0 4.4 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 CAM44415.2 - 9.1e-21 74.1 0.1 3.8e-20 72.1 0.1 2.2 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain FATC PF02260.20 CAM44415.2 - 3e-15 55.7 0.2 7.7e-15 54.4 0.2 1.8 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 CAM44415.2 - 0.00075 19.8 7.9 3 8.3 0.1 6.0 7 0 0 7 7 7 2 HEAT repeats HEAT PF02985.22 CAM44415.2 - 0.97 9.9 6.6 27 5.4 0.1 6.3 6 0 0 6 6 6 0 HEAT repeat FANCI_S2 PF14676.6 CAM44415.2 - 2.1 8.7 5.8 63 3.8 0.1 5.1 4 1 1 5 5 5 0 FANCI solenoid 2 PEX11 PF05648.14 CAM44416.1 - 0.013 14.9 0.3 0.023 14.1 0.3 1.6 1 1 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) UTP15_C PF09384.10 CAM44416.1 - 0.028 14.1 0.2 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 UTP15 C terminal Flexi_CP PF00286.20 CAM44416.1 - 0.074 13.0 0.2 1.9 8.4 0.0 2.1 2 0 0 2 2 2 0 Viral coat protein HECT PF00632.25 CAM44417.2 - 2e-53 181.9 0.0 5.3e-53 180.5 0.0 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 CAM44417.2 - 5.7e-42 142.6 0.0 2.6e-16 59.8 0.0 4.1 4 0 0 4 4 4 3 SPRY domain Laminin_G_3 PF13385.6 CAM44417.2 - 1.5e-16 60.9 0.0 1.8e-07 31.4 0.0 3.4 4 0 0 4 4 4 2 Concanavalin A-like lectin/glucanases superfamily Pox_MCEL PF03291.16 CAM44418.1 - 0.075 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme PH_11 PF15413.6 CAM44419.1 - 0.0045 17.4 0.0 0.0089 16.4 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain CAF1 PF04857.20 CAM44421.2 - 1.5e-66 224.8 0.1 2e-66 224.4 0.1 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease DNA_meth_N PF18284.1 CAM44421.2 - 0.059 13.3 0.4 0.87 9.5 0.0 2.5 2 0 0 2 2 2 0 DNA methylase N-terminal domain Tma16 PF11176.8 CAM44422.1 - 4.9e-23 81.6 0.1 4.9e-23 81.6 0.1 1.8 2 0 0 2 2 2 1 Translation machinery-associated protein 16 RabGAP-TBC PF00566.18 CAM44423.1 - 2e-13 50.5 0.4 3.3e-13 49.8 0.4 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ArfGap PF01412.18 CAM44423.1 - 0.046 13.8 0.7 0.3 11.2 0.1 2.3 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Nucleoporin_FG PF13634.6 CAM44423.1 - 2.6 9.0 34.8 5.2 8.0 23.6 2.8 1 1 1 2 2 2 0 Nucleoporin FG repeat region DUF1126 PF06565.12 CAM44424.1 - 3.9e-62 206.6 0.0 2.6e-22 78.6 0.0 3.5 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_7 PF13499.6 CAM44424.1 - 1.2e-05 25.7 0.1 0.00088 19.7 0.0 3.4 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.6 CAM44424.1 - 0.00023 21.0 0.3 0.42 10.5 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain pair Mac-1 PF09028.10 CAM44424.1 - 0.032 13.3 0.0 0.053 12.6 0.0 1.3 1 0 0 1 1 1 0 Mac 1 EF-hand_6 PF13405.6 CAM44424.1 - 0.064 13.2 0.3 37 4.6 0.0 4.0 4 0 0 4 4 4 0 EF-hand domain MTHFR PF02219.17 CAM44425.1 - 7.1e-94 314.3 0.0 8.6e-94 314.1 0.0 1.0 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Ribosomal_S8e PF01201.22 CAM44426.1 - 7.3e-45 152.5 3.3 7.3e-45 152.5 3.3 1.5 1 1 0 1 1 1 1 Ribosomal protein S8e DUF3746 PF12562.8 CAM44426.1 - 0.085 12.8 0.5 0.41 10.6 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3746) Ribosomal_L26 PF16906.5 CAM44426.1 - 0.15 12.5 6.8 2.9 8.4 3.0 2.4 2 0 0 2 2 2 0 Ribosomal proteins L26 eukaryotic, L24P archaeal CCDC-167 PF15188.6 CAM44426.1 - 0.16 12.4 2.8 0.33 11.3 2.8 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Peptidase_S46 PF10459.9 CAM44426.1 - 0.42 9.2 8.0 0.5 8.9 8.0 1.1 1 0 0 1 1 1 0 Peptidase S46 HU-CCDC81_euk_2 PF18289.1 CAM44427.1 - 1.4e-09 37.9 0.0 2.4e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 TB2_DP1_HVA22 PF03134.19 CAM44428.1 - 0.085 12.8 2.2 0.12 12.3 2.0 1.5 1 1 0 1 1 1 0 TB2/DP1, HVA22 family Sec23_trunk PF04811.15 CAM44429.1 - 1.8e-50 171.8 0.0 3.4e-50 170.9 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CAM44429.1 - 5.2e-23 80.8 0.1 2.9e-22 78.4 0.1 2.2 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 CAM44429.1 - 5e-21 75.3 1.4 1.4e-20 73.8 1.4 1.9 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 CAM44429.1 - 2.1e-11 43.7 3.4 3e-11 43.2 0.7 2.6 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CAM44429.1 - 3.2e-06 26.9 0.0 9.5e-06 25.4 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat ComP_DUS PF16732.5 CAM44430.1 - 0.041 14.8 0.3 0.33 11.9 0.0 2.4 2 1 1 3 3 3 0 Type IV minor pilin ComP, DNA uptake sequence receptor DUF1539 PF07560.11 CAM44430.1 - 0.21 11.7 0.8 7.1 6.7 0.1 2.2 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1539) His_Phos_2 PF00328.22 CAM44432.1 - 1.6e-14 54.1 0.6 7.8e-08 32.1 0.0 2.7 1 1 1 3 3 3 2 Histidine phosphatase superfamily (branch 2) WGR PF05406.15 CAM44433.1 - 0.16 12.1 0.3 0.28 11.2 0.3 1.4 1 0 0 1 1 1 0 WGR domain Pkinase PF00069.25 CAM44434.1 - 4.3e-61 206.6 0.0 5.3e-61 206.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM44434.1 - 2.2e-25 89.4 0.0 3e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM44434.1 - 3e-09 36.6 0.0 5e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CAM44434.1 - 8.5e-05 22.0 0.7 0.00016 21.1 0.7 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CAM44434.1 - 0.034 14.1 0.6 2.1 8.2 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family His_Phos_2 PF00328.22 CAM44435.1 - 2.1e-15 57.0 2.1 3.2e-08 33.3 0.0 3.1 1 1 1 3 3 3 3 Histidine phosphatase superfamily (branch 2) UFD1 PF03152.14 CAM44436.1 - 4.6e-47 159.7 0.0 6.1e-47 159.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 NCE101 PF11654.8 CAM44437.1 - 0.14 11.9 0.2 0.58 9.9 0.1 2.1 2 0 0 2 2 2 0 Non-classical export protein 1 Axin_b-cat_bind PF08833.10 CAM44437.1 - 0.26 11.4 1.6 12 6.1 0.5 2.8 2 0 0 2 2 2 0 Axin beta-catenin binding domain PCI PF01399.27 CAM44438.1 - 0.048 14.2 0.0 0.099 13.2 0.0 1.5 1 0 0 1 1 1 0 PCI domain DUF3551 PF12071.8 CAM44440.1 - 0.039 14.0 0.2 0.074 13.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3551) Phage_holin_3_6 PF07332.11 CAM44440.1 - 0.12 12.4 2.7 0.17 11.9 1.5 1.7 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III SLC3A2_N PF16028.5 CAM44440.1 - 0.28 10.8 7.1 4.8 6.8 0.9 2.5 1 1 1 2 2 2 0 Solute carrier family 3 member 2 N-terminus 2TM PF13239.6 CAM44440.1 - 1 9.7 9.3 0.2 12.0 5.7 1.7 1 1 1 2 2 2 0 2TM domain SdpI PF13630.6 CAM44440.1 - 1.7 8.8 8.0 0.51 10.5 4.8 1.7 1 1 1 2 2 2 0 SdpI/YhfL protein family COX7a PF02238.15 CAM44440.1 - 6.8 7.2 8.8 0.25 11.7 0.7 2.6 2 1 1 3 3 3 0 Cytochrome c oxidase subunit VII Myb_DNA-bind_7 PF15963.5 CAM44442.1 - 7.1e-25 86.7 0.5 1.3e-24 85.9 0.5 1.4 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 CAM44442.1 - 3.1e-06 27.3 0.0 6e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CAM44442.1 - 0.034 14.4 0.0 0.069 13.4 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF1963 PF09234.10 CAM44442.1 - 1.7 9.1 4.3 1.4 9.3 1.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1963) DLH PF01738.18 CAM44443.1 - 6.3e-25 88.0 0.0 7.3e-25 87.8 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 CAM44443.1 - 0.00051 19.8 0.0 0.00098 18.8 0.0 1.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.11 CAM44443.1 - 0.0055 16.7 0.0 0.0079 16.1 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF3530 PF12048.8 CAM44443.1 - 0.0081 15.6 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) DUF1847 PF08901.11 CAM44443.1 - 0.12 12.0 0.0 0.65 9.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1847) YdfZ PF14001.6 CAM44443.1 - 0.14 12.6 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 YdfZ protein PCMT PF01135.19 CAM44444.1 - 1.7e-47 161.9 0.0 2.4e-47 161.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 CAM44444.1 - 0.00057 20.9 0.0 0.00094 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF4491 PF14898.6 CAM44444.1 - 0.0013 19.1 0.1 1.1 9.8 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4491) Methyltransf_32 PF13679.6 CAM44444.1 - 0.0035 17.3 0.0 0.0049 16.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAM44444.1 - 0.01 16.5 0.0 0.02 15.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 CAM44444.1 - 0.047 13.5 0.0 0.066 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 CAM44444.1 - 0.081 13.6 0.0 0.18 12.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 CAM44444.1 - 0.12 12.2 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ACBP PF00887.19 CAM44445.2 - 1.1e-14 54.4 0.1 2.1e-14 53.5 0.1 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein SRP-alpha_N PF04086.13 CAM44445.2 - 0.24 11.3 0.0 0.31 10.9 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Peptidase_S8 PF00082.22 CAM44446.1 - 0.03 13.6 4.9 0.042 13.1 4.9 1.2 1 0 0 1 1 1 0 Subtilase family UFD1 PF03152.14 CAM44447.1 - 1.3e-45 154.9 0.0 1.7e-45 154.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 NYD-SP28_assoc PF14775.6 CAM44448.1 - 2e-20 72.7 2.3 2e-20 72.7 2.3 4.2 5 1 1 6 6 6 1 Sperm tail C-terminal domain NYD-SP28 PF14772.6 CAM44448.1 - 6.2e-18 64.7 8.9 6.2e-18 64.7 8.9 5.1 5 0 0 5 5 5 2 Sperm tail DUF948 PF06103.11 CAM44448.1 - 2.6 8.4 9.6 1.3 9.3 1.5 3.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Glyco_trans_1_2 PF13524.6 CAM44448.1 - 5.1 7.6 9.1 0.97 9.9 1.0 3.4 2 0 0 2 2 2 0 Glycosyl transferases group 1 Mito_carr PF00153.27 CAM44450.1 - 1.2e-31 108.5 4.8 4.6e-12 45.7 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein KASH PF10541.9 CAM44451.2 - 0.14 12.5 0.2 0.14 12.5 0.2 4.8 6 0 0 6 6 6 0 Nuclear envelope localisation domain SAS-6_N PF16531.5 CAM44453.1 - 5.4e-23 81.4 0.2 8e-23 80.8 0.2 1.3 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal CSD PF00313.22 CAM44453.1 - 0.081 12.8 0.0 0.29 11.0 0.0 1.9 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain Metalloenzyme PF01676.18 CAM44454.1 - 1e-81 274.0 0.0 1.2e-81 273.8 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.13 CAM44454.1 - 3.6e-60 203.1 0.1 5.3e-60 202.5 0.1 1.3 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.22 CAM44454.1 - 0.00044 19.9 0.0 0.00089 18.9 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase PglZ PF08665.12 CAM44454.1 - 0.0057 16.8 0.1 0.01 15.9 0.1 1.3 1 0 0 1 1 1 1 PglZ domain PGM_PMM_II PF02879.16 CAM44454.1 - 0.084 13.5 1.2 6.3 7.5 0.0 3.8 5 0 0 5 5 5 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II FtsJ PF01728.19 CAM44455.1 - 2.5e-26 92.9 0.0 2.6e-25 89.5 0.0 2.0 2 0 0 2 2 2 1 FtsJ-like methyltransferase Cyt-b5 PF00173.28 CAM44456.2 - 4.5e-12 45.9 0.0 5.8e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Spc7 PF08317.11 CAM44457.1 - 0.0052 15.7 6.3 0.0052 15.7 6.3 2.0 1 1 1 2 2 2 1 Spc7 kinetochore protein Val_tRNA-synt_C PF10458.9 CAM44457.1 - 0.013 15.7 0.2 0.013 15.7 0.2 3.6 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm GrpE PF01025.19 CAM44457.1 - 0.05 13.3 0.9 0.05 13.3 0.9 2.7 1 1 1 2 2 2 0 GrpE Peptidase_S46 PF10459.9 CAM44457.1 - 0.064 11.9 8.9 0.076 11.7 8.9 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF812 PF05667.11 CAM44457.1 - 0.13 11.1 14.1 0.18 10.6 14.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) KIAA1430 PF13879.6 CAM44457.1 - 0.23 12.3 4.3 0.19 12.5 2.5 1.7 1 1 1 2 2 2 0 KIAA1430 homologue UPF0242 PF06785.11 CAM44457.1 - 0.55 10.3 15.6 1.1 9.3 15.6 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ACCA PF03255.14 CAM44457.1 - 0.74 9.7 9.1 0.84 9.5 3.1 2.6 1 1 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Exonuc_VII_L PF02601.15 CAM44457.1 - 1.4 8.4 9.3 1.8 8.0 9.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit HABP4_PAI-RBP1 PF04774.15 CAM44457.1 - 3.8 8.4 10.8 6.8 7.6 10.7 1.4 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family CENP-H PF05837.12 CAM44457.1 - 4.2 7.8 18.8 12 6.3 3.1 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) FAM76 PF16046.5 CAM44457.1 - 7 5.9 11.9 3.6 6.9 7.5 2.0 1 1 1 2 2 2 0 FAM76 protein YlqD PF11068.8 CAM44457.1 - 8.6 6.7 12.7 5.5 7.4 8.8 2.0 1 1 0 2 2 2 0 YlqD protein Solute_trans_a PF03619.16 CAM44458.1 - 1e-77 261.3 15.1 1.7e-77 260.6 15.1 1.3 1 0 0 1 1 1 1 Organic solute transporter Ostalpha WBS28 PF15164.6 CAM44458.1 - 0.03 13.6 1.6 0.7 9.1 0.3 2.8 2 1 0 2 2 2 0 Williams-Beuren syndrome chromosomal region 28 protein homologue NUFIP1 PF10453.9 CAM44458.1 - 0.28 11.1 0.5 0.45 10.4 0.5 1.3 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) DUF4179 PF13786.6 CAM44458.1 - 0.89 10.1 4.1 59 4.2 4.1 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) DUF3382 PF11862.8 CAM44458.1 - 1.7 8.9 5.3 11 6.4 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) DUF3671 PF12420.8 CAM44458.1 - 7.6 6.7 11.5 6.2 6.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function AAA_22 PF13401.6 CAM44459.1 - 8.2e-06 26.1 0.0 2.4e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CAM44459.1 - 0.0013 19.2 0.3 0.0036 17.7 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 CAM44459.1 - 0.076 12.6 0.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CAM44459.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA12 PF10443.9 CAM44459.1 - 0.17 10.6 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 RNA12 protein DNA_pol3_delta2 PF13177.6 CAM44460.1 - 3.8e-13 49.5 0.0 6.2e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 CAM44460.1 - 1.6e-06 28.6 0.0 5.7e-06 26.8 0.0 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 CAM44460.1 - 0.00013 22.3 0.0 0.00028 21.2 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.15 CAM44460.1 - 0.0006 19.8 0.0 0.0016 18.4 0.0 1.7 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_24 PF13479.6 CAM44460.1 - 0.00085 19.1 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CAM44460.1 - 0.0011 19.0 0.0 0.0061 16.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CAM44460.1 - 0.0035 17.1 0.0 0.23 11.2 0.0 3.0 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 CAM44460.1 - 0.004 16.6 0.0 0.12 11.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 CAM44460.1 - 0.0044 17.4 0.0 0.1 13.0 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain Sigma54_activ_2 PF14532.6 CAM44460.1 - 0.018 15.2 0.0 0.61 10.2 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activat PF00158.26 CAM44460.1 - 0.033 13.9 0.0 3.7 7.2 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_22 PF13401.6 CAM44460.1 - 0.079 13.2 0.0 0.49 10.7 0.0 2.3 2 1 0 2 2 2 0 AAA domain Peptidase_S9_N PF02897.15 CAM44463.2 - 2.3e-93 313.2 5.7 3e-93 312.9 5.7 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 CAM44463.2 - 3.9e-61 206.2 0.1 8.2e-61 205.2 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.20 CAM44463.2 - 0.00095 18.9 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 CAM44463.2 - 0.044 13.0 0.0 0.087 12.1 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 OSCP PF00213.18 CAM44464.1 - 1.2e-07 32.0 1.2 4.6e-07 30.1 1.2 1.9 1 1 0 1 1 1 1 ATP synthase delta (OSCP) subunit Adaptin_N PF01602.20 CAM44465.2 - 2e-99 333.6 2.7 2.4e-99 333.3 2.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CAM44465.2 - 5.5e-48 163.1 0.5 4.5e-47 160.1 0.0 2.6 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CAM44465.2 - 1.7e-10 41.2 4.1 3.6e-05 24.1 0.0 5.1 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.22 CAM44465.2 - 1.6e-06 27.9 8.0 0.046 14.0 0.0 5.6 6 0 0 6 6 6 2 HEAT repeat RTP1_C1 PF10363.9 CAM44465.2 - 0.005 17.0 0.1 0.85 9.8 0.0 3.2 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 CAP18_C PF12153.8 CAM44465.2 - 0.15 12.0 0.4 0.37 10.7 0.4 1.6 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) VHS PF00790.19 CAM44465.2 - 0.17 11.8 1.0 0.61 9.9 0.1 2.3 2 0 0 2 2 2 0 VHS domain HEAT_EZ PF13513.6 CAM44465.2 - 0.25 11.9 3.5 11 6.7 0.1 4.3 4 1 1 5 5 5 0 HEAT-like repeat NIF PF03031.18 CAM44466.1 - 9.1e-32 110.0 0.0 1.3e-31 109.5 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase SET PF00856.28 CAM44467.1 - 3e-15 57.0 0.0 2.7e-14 53.9 0.0 2.1 1 1 0 1 1 1 1 SET domain E3_UFM1_ligase PF09743.9 CAM44469.1 - 3.1e-75 253.3 0.1 6.5e-75 252.2 0.1 1.6 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 RseA_N PF03872.13 CAM44469.1 - 0.04 14.4 0.3 0.49 10.9 0.1 2.7 2 0 0 2 2 2 0 Anti sigma-E protein RseA, N-terminal domain NurA PF09376.10 CAM44469.1 - 0.18 11.5 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 NurA domain VASP_tetra PF08776.11 CAM44469.1 - 0.39 10.3 2.4 9.8 5.8 0.2 3.6 4 0 0 4 4 4 0 VASP tetramerisation domain 4HBT PF03061.22 CAM44470.1 - 2.9e-05 24.3 0.0 4.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 CAM44470.1 - 0.0031 17.6 0.0 0.0043 17.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) TMEM65 PF10507.9 CAM44473.1 - 8.5e-38 128.7 2.3 1.5e-37 127.8 2.3 1.4 1 0 0 1 1 1 1 Transmembrane protein 65 EF-hand_1 PF00036.32 CAM44473.1 - 1e-07 31.0 0.1 0.0015 18.0 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CAM44473.1 - 6.4e-05 22.6 0.5 0.013 15.4 0.0 3.2 4 0 0 4 4 4 1 EF-hand domain EF-hand_7 PF13499.6 CAM44473.1 - 6.8e-05 23.2 1.1 0.097 13.1 0.1 3.4 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_14 PF17959.1 CAM44473.1 - 0.0047 17.2 0.3 0.023 15.1 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain Abhydrolase_9 PF10081.9 CAM44473.1 - 0.019 14.0 0.2 0.028 13.5 0.2 1.1 1 0 0 1 1 1 0 Alpha/beta-hydrolase family EF-hand_5 PF13202.6 CAM44473.1 - 0.041 13.4 0.4 0.4 10.2 0.0 2.6 3 0 0 3 3 3 0 EF hand Ppx-GppA PF02541.16 CAM44473.1 - 0.14 11.6 0.1 0.21 11.0 0.1 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family RNA_lig_T4_1 PF09511.10 CAM44475.1 - 5.9e-30 104.8 0.0 1.1e-29 103.8 0.0 1.5 1 0 0 1 1 1 1 RNA ligase AAA_33 PF13671.6 CAM44475.1 - 1.6e-11 44.6 0.5 1.6e-11 44.6 0.5 2.1 2 0 0 2 2 2 1 AAA domain 6PF2K PF01591.18 CAM44475.1 - 2.5e-08 33.5 0.0 5.1e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_18 PF13238.6 CAM44475.1 - 2.4e-07 31.4 0.0 5.1e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CAM44475.1 - 0.00034 20.6 0.0 0.00095 19.1 0.0 1.8 1 0 0 1 1 1 1 NACHT domain APS_kinase PF01583.20 CAM44475.1 - 0.00095 19.1 0.0 0.0032 17.4 0.0 1.9 1 1 0 1 1 1 1 Adenylylsulphate kinase KTI12 PF08433.10 CAM44475.1 - 0.0012 18.3 0.0 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.6 CAM44475.1 - 0.0015 19.0 0.0 0.0031 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 CAM44475.1 - 0.0024 17.5 1.9 0.0072 15.9 0.2 2.4 1 1 2 3 3 3 1 AAA domain CPT PF07931.12 CAM44475.1 - 0.021 14.7 0.6 0.055 13.3 0.2 2.0 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_28 PF13521.6 CAM44475.1 - 0.023 14.9 0.0 0.077 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.15 CAM44475.1 - 0.046 13.1 0.0 0.087 12.1 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_22 PF13401.6 CAM44475.1 - 0.047 14.0 0.1 0.22 11.8 0.1 2.2 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CAM44475.1 - 0.047 14.2 0.0 0.16 12.5 0.0 1.9 2 0 0 2 2 1 0 ABC transporter Zeta_toxin PF06414.12 CAM44475.1 - 0.062 12.6 0.0 0.18 11.1 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_5 PF07728.14 CAM44475.1 - 0.09 12.8 0.0 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 CAM44475.1 - 0.12 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1 PF01926.23 CAM44475.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase EVE PF01878.18 CAM44477.1 - 8.6e-53 178.2 0.7 9.9e-53 178.1 0.7 1.0 1 0 0 1 1 1 1 EVE domain Bromodomain PF00439.25 CAM44478.1 - 1.1e-17 63.8 0.1 2.2e-17 62.9 0.1 1.4 1 0 0 1 1 1 1 Bromodomain Nucleoporin_N PF08801.11 CAM44479.1 - 1.5e-58 198.6 0.0 2.5e-58 197.9 0.0 1.3 1 0 0 1 1 1 1 Nup133 N terminal like LRR_4 PF12799.7 CAM44480.1 - 0.0024 18.2 0.0 0.11 12.9 0.0 2.5 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) Cpn60_TCP1 PF00118.24 CAM44481.1 - 2.9e-152 507.7 10.1 3.3e-152 507.5 10.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF374 PF04028.13 CAM44481.1 - 0.13 11.8 0.1 0.85 9.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF374) Ribosomal_L1 PF00687.21 CAM44482.1 - 1.6e-19 70.5 0.0 2e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family zf-C2H2_6 PF13912.6 CAM44483.1 - 5.6e-05 23.0 12.5 0.00038 20.4 2.5 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger SSB PF00436.25 CAM44483.1 - 0.0041 17.1 0.0 0.0087 16.1 0.0 1.5 1 0 0 1 1 1 1 Single-strand binding protein family zf-C2H2_2 PF12756.7 CAM44483.1 - 0.0054 17.0 0.4 1.8 9.0 0.1 2.3 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 CAM44483.1 - 0.0088 16.4 6.7 0.48 10.9 0.7 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 CAM44483.1 - 0.047 14.0 2.6 2.2 8.6 0.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 CAM44483.1 - 0.047 14.5 12.6 0.35 11.8 3.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Flag1_repress PF03614.13 CAM44483.1 - 0.13 12.1 0.0 2.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Repressor of phase-1 flagellin zf-C2H2 PF00096.26 CAM44483.1 - 0.2 12.2 11.1 1.5 9.4 3.5 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf_C2H2_ZHX PF18387.1 CAM44483.1 - 0.32 10.7 3.2 1.2 8.8 0.3 2.3 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 CAM44483.1 - 1.3 9.4 5.2 14 6.1 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 CAM44483.1 - 2.5 8.7 8.2 2.6 8.6 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger double domain DUF629 PF04780.12 CAM44483.1 - 6.8 5.1 5.3 2.1 6.8 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF629) Thioredoxin PF00085.20 CAM44485.1 - 3.6e-60 200.4 0.9 1.1e-30 105.6 0.1 3.9 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 CAM44485.1 - 5.2e-28 98.2 0.1 2.6e-19 69.8 0.0 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CAM44485.1 - 1.6e-15 57.5 2.2 4.9e-08 33.4 0.1 3.5 2 2 0 2 2 2 2 Thioredoxin-like domain AhpC-TSA PF00578.21 CAM44485.1 - 2.4e-11 43.7 0.9 4.9e-05 23.2 0.0 3.7 4 0 0 4 4 4 2 AhpC/TSA family Thioredoxin_7 PF13899.6 CAM44485.1 - 3.1e-10 40.1 0.1 0.0002 21.5 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.6 CAM44485.1 - 7.4e-10 39.0 1.6 0.026 14.8 0.0 5.0 4 2 1 5 5 5 3 Thioredoxin-like OST3_OST6 PF04756.13 CAM44485.1 - 3.1e-06 26.8 0.1 0.0072 15.7 0.0 2.7 2 1 1 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 CAM44485.1 - 7.9e-06 25.7 0.0 0.048 13.4 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin TraF PF13728.6 CAM44485.1 - 8.1e-06 25.8 0.1 0.018 14.9 0.0 3.4 3 1 0 3 3 3 1 F plasmid transfer operon protein Redoxin PF08534.10 CAM44485.1 - 7.2e-05 22.5 0.9 0.0081 15.9 0.0 3.2 3 0 0 3 3 3 1 Redoxin Thioredoxin_3 PF13192.6 CAM44485.1 - 0.00016 21.6 0.5 0.43 10.6 0.1 3.5 3 0 0 3 3 3 2 Thioredoxin domain HyaE PF07449.11 CAM44485.1 - 0.019 14.9 0.0 0.21 11.6 0.0 2.5 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Sigma70_r4_2 PF08281.12 CAM44485.1 - 0.17 11.6 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 FleQ PF06490.11 CAM44485.1 - 0.17 12.2 0.0 0.73 10.2 0.0 2.0 2 0 0 2 2 2 0 Flagellar regulatory protein FleQ FA_desaturase PF00487.24 CAM44486.1 - 4.5e-31 108.6 12.7 8.6e-31 107.7 12.7 1.5 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 CAM44486.1 - 6.5e-10 39.0 0.0 1.3e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3788 PF12663.7 CAM44487.1 - 0.083 12.9 0.1 0.3 11.0 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3788) KASH_CCD PF14662.6 CAM44487.1 - 0.14 12.0 36.6 0.071 12.9 2.0 4.4 1 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH Mt_ATP-synt_D PF05873.12 CAM44487.1 - 0.49 10.2 5.9 0.78 9.6 0.1 3.4 3 1 0 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) Methyltransf_23 PF13489.6 CAM44488.1 - 0.033 14.0 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF3285 PF11688.8 CAM44488.1 - 0.058 13.3 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3285) eIF-3c_N PF05470.12 CAM44489.1 - 4.1e-21 74.9 2.0 1.5e-15 56.6 0.0 2.3 2 1 0 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 CAM44489.1 - 0.024 15.1 0.1 0.1 13.1 0.0 2.1 2 0 0 2 2 2 0 PCI domain 6PF2K PF01591.18 CAM44489.1 - 0.078 12.3 0.6 0.3 10.3 0.2 1.9 2 0 0 2 2 2 0 6-phosphofructo-2-kinase RRM_1 PF00076.22 CAM44490.1 - 0.0038 17.0 0.0 0.0085 15.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CAM44490.1 - 0.02 15.0 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 RRM_5 PF13893.6 CAM44490.1 - 0.032 13.8 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MOZ_SAS PF01853.18 CAM44491.1 - 1.4e-46 158.4 0.0 1.7e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 MOZ/SAS family zf-C4_ClpX PF06689.13 CAM44491.1 - 0.0074 16.1 0.7 0.015 15.2 0.2 1.8 2 0 0 2 2 2 1 ClpX C4-type zinc finger zf-MYST PF17772.1 CAM44491.1 - 0.0096 15.5 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 CAM44491.1 - 0.053 13.9 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CLN3 PF02487.17 CAM45044.2 - 1.4e-48 165.9 20.0 2.3e-48 165.3 18.4 2.0 2 1 0 2 2 2 1 CLN3 protein Ribosomal_L5_C PF00673.21 CAM45046.1 - 8.3e-21 74.0 0.0 1.3e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CAM45046.1 - 9.4e-18 64.3 0.2 2.1e-16 60.0 0.0 2.3 2 0 0 2 2 2 1 Ribosomal protein L5 SET PF00856.28 CAM45047.1 - 0.00013 22.4 0.0 0.00015 22.2 0.0 1.3 1 0 0 1 1 1 1 SET domain R3H PF01424.22 CAM45049.2 - 1.5e-11 44.1 0.1 3.1e-11 43.1 0.1 1.6 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 CAM45049.2 - 1.5e-11 44.1 58.4 5.5e-06 26.3 14.2 15.9 16 1 1 17 17 17 9 NF-X1 type zinc finger HopA1 PF17914.1 CAM45049.2 - 0.082 12.7 0.1 8 6.2 0.0 2.6 2 0 0 2 2 2 0 HopA1 effector protein family Rad10 PF03834.14 CAM45050.1 - 0.00016 21.7 0.0 0.00024 21.1 0.0 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) DnaJ_C PF01556.18 CAM45051.1 - 1.4e-28 99.8 0.0 1.9e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 CAM45051.1 - 1.2e-11 44.8 8.9 2.8e-11 43.6 8.9 1.7 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CAM45051.1 - 0.0097 15.8 5.8 0.016 15.1 1.1 2.4 1 1 1 2 2 2 1 Tryptophan RNA-binding attenuator protein inhibitory protein DUF3556 PF12077.8 CAM45051.1 - 0.045 12.2 0.1 0.06 11.8 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein of unknown function (DUF3556) HypA PF01155.19 CAM45051.1 - 0.72 9.9 5.2 1 9.4 3.2 2.3 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Pox_MCEL PF03291.16 CAM45052.1 - 2.2e-44 151.9 0.0 3.3e-44 151.3 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme mRNA_cap_C PF03919.15 CAM45052.1 - 1.4e-07 32.1 0.0 3.6e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain mRNA_cap_enzyme PF01331.19 CAM45052.1 - 2.5e-07 30.7 0.0 0.023 14.5 0.0 2.5 2 0 0 2 2 2 2 mRNA capping enzyme, catalytic domain Methyltransf_25 PF13649.6 CAM45052.1 - 0.0011 19.6 0.2 0.015 16.0 0.0 3.0 2 1 0 2 2 2 1 Methyltransferase domain GATase PF00117.28 CAM45055.1 - 5.2e-37 127.5 0.0 9.5e-37 126.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 CAM45055.1 - 7.8e-16 57.9 0.0 2.1e-08 34.1 0.0 2.9 2 1 0 2 2 2 2 GMP synthase C terminal domain Peptidase_C26 PF07722.13 CAM45055.1 - 1.3e-14 54.5 0.0 5.4e-14 52.5 0.0 2.1 1 1 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.17 CAM45055.1 - 2.6e-07 30.0 0.0 0.00016 20.9 0.0 2.3 2 0 0 2 2 2 2 NAD synthase QueC PF06508.13 CAM45055.1 - 3e-05 23.6 0.0 0.00011 21.8 0.0 1.9 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC ThiI PF02568.14 CAM45055.1 - 0.00017 21.3 0.2 0.00079 19.1 0.1 2.1 3 0 0 3 3 3 1 Thiamine biosynthesis protein (ThiI) Arginosuc_synth PF00764.19 CAM45055.1 - 0.0014 18.0 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase PAPS_reduct PF01507.19 CAM45055.1 - 0.0045 17.0 0.0 0.0086 16.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.20 CAM45055.1 - 0.0071 16.1 0.0 0.025 14.4 0.1 1.8 2 0 0 2 2 2 1 PP-loop family tRNA_Me_trans PF03054.16 CAM45055.1 - 0.019 13.8 0.0 0.047 12.5 0.1 1.6 2 0 0 2 2 2 0 tRNA methyl transferase Asn_synthase PF00733.21 CAM45055.1 - 0.11 12.2 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 Asparagine synthase GP79 PF17463.2 CAM45055.1 - 0.11 12.5 0.3 0.33 11.0 0.3 1.8 1 0 0 1 1 1 0 Gene product 79 Tup_N PF08581.10 CAM45056.1 - 0.0085 16.4 11.6 0.062 13.6 0.2 3.1 2 1 1 3 3 3 2 Tup N-terminal Med20 PF08612.11 CAM45056.1 - 0.097 12.0 0.5 0.17 11.2 0.5 1.7 1 1 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex NRN1 PF15056.6 CAM45056.1 - 0.21 11.7 2.5 0.19 11.8 0.5 1.9 2 1 0 2 2 2 0 Neuritin protein family DUF3584 PF12128.8 CAM45056.1 - 1.1 6.7 30.6 1.8 5.9 30.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.11 CAM45056.1 - 1.7 7.5 29.7 1.3 7.9 18.2 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 CAM45056.1 - 2.5 8.2 14.6 0.51 10.4 3.8 3.0 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Golgin_A5 PF09787.9 CAM45056.1 - 4.9 6.5 29.1 3.7 6.9 15.6 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 zf-CCCH PF00642.24 CAM45057.1 - 4.1e-05 23.4 16.9 0.0072 16.2 5.8 2.7 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CAM45057.1 - 0.0015 19.2 5.7 0.041 14.6 1.6 2.5 2 0 0 2 2 2 2 Torus domain BAG PF02179.16 CAM45058.1 - 1.1e-05 25.7 0.1 2.2e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 BAG domain Dcc1 PF09724.9 CAM45059.1 - 6.4e-53 180.2 0.0 7.5e-53 180.0 0.0 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 zf-CCCH_4 PF18044.1 CAM45060.1 - 2.8e-08 33.4 12.8 0.00021 21.0 3.6 3.0 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 CAM45060.1 - 1.1e-06 28.4 19.6 1.6e-05 24.7 2.0 3.9 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CAM45060.1 - 8e-06 25.7 17.4 0.004 17.2 3.2 3.2 3 0 0 3 3 3 2 Zinc finger domain Torus PF16131.5 CAM45060.1 - 2.3e-05 25.0 0.5 0.061 14.0 0.3 2.6 2 0 0 2 2 2 2 Torus domain Mitofilin PF09731.9 CAM45062.1 - 0.0015 17.4 3.5 0.0016 17.4 3.5 1.2 1 0 0 1 1 1 1 Mitochondrial inner membrane protein ApoO PF09769.9 CAM45062.1 - 0.0028 17.6 4.0 0.0054 16.7 2.0 2.3 1 1 2 3 3 3 2 Apolipoprotein O ApoLp-III PF07464.11 CAM45062.1 - 0.0033 17.5 5.0 0.0033 17.5 5.0 2.4 3 0 0 3 3 3 1 Apolipophorin-III precursor (apoLp-III) Apolipoprotein PF01442.18 CAM45062.1 - 0.0036 17.2 7.3 0.01 15.7 7.3 1.7 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain ATG_C PF09333.11 CAM45062.1 - 0.0047 17.2 4.6 0.098 13.0 2.8 2.6 1 1 1 2 2 2 1 Autophagy-related protein C terminal domain DUF883 PF05957.13 CAM45062.1 - 0.0054 17.3 10.9 0.27 11.8 3.1 2.5 1 1 2 3 3 3 3 Bacterial protein of unknown function (DUF883) Alba PF01918.21 CAM45062.1 - 0.012 15.4 0.4 0.33 10.8 0.1 3.0 2 1 0 2 2 2 0 Alba KfrA_N PF11740.8 CAM45062.1 - 0.014 16.0 5.6 0.038 14.7 5.6 1.8 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term ATP-synt_B PF00430.18 CAM45062.1 - 0.016 15.3 8.7 0.016 15.3 8.7 1.8 2 0 0 2 2 1 0 ATP synthase B/B' CF(0) Prominin PF05478.11 CAM45062.1 - 0.02 12.9 1.6 0.026 12.5 1.6 1.2 1 0 0 1 1 1 0 Prominin Activator-TraM PF11657.8 CAM45062.1 - 0.021 14.7 1.6 0.048 13.5 1.6 1.7 1 0 0 1 1 1 0 Transcriptional activator TraM DUF2564 PF10819.8 CAM45062.1 - 0.024 15.0 8.5 0.32 11.4 2.7 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2564) ZYG-11_interact PF05884.12 CAM45062.1 - 0.025 14.0 0.6 0.043 13.2 0.6 1.3 1 0 0 1 1 1 0 Interactor of ZYG-11 DUF3987 PF13148.6 CAM45062.1 - 0.034 13.2 1.2 0.046 12.7 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF3926 PF13080.6 CAM45062.1 - 0.074 13.0 0.3 1.7 8.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3926) YtxH PF12732.7 CAM45062.1 - 0.09 13.3 9.8 12 6.5 9.8 2.4 1 1 0 1 1 1 0 YtxH-like protein DUF5082 PF16888.5 CAM45062.1 - 0.098 12.9 3.8 0.056 13.7 1.9 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF5082) Hydrolase_6 PF13344.6 CAM45062.1 - 0.1 12.7 0.3 0.37 10.9 0.0 2.1 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF357 PF04010.13 CAM45062.1 - 0.15 12.1 1.4 0.78 9.9 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF357) LXG PF04740.12 CAM45062.1 - 0.23 11.1 5.0 0.15 11.8 2.8 1.9 2 1 0 2 2 1 0 LXG domain of WXG superfamily RRF PF01765.19 CAM45062.1 - 0.25 11.3 8.9 0.35 10.8 1.4 2.2 1 1 1 2 2 2 0 Ribosome recycling factor DivIVA PF05103.13 CAM45062.1 - 0.34 11.0 9.2 1.8 8.6 9.2 2.2 1 1 0 1 1 1 0 DivIVA protein Uso1_p115_C PF04871.13 CAM45062.1 - 0.47 10.8 8.7 1.4 9.3 8.6 1.9 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region SCAB_CC PF16712.5 CAM45062.1 - 0.58 10.0 11.6 2.1 8.2 1.3 2.5 2 1 1 3 3 3 0 Coiled-coil regions of plant-specific actin-binding protein Phasin PF05597.11 CAM45062.1 - 0.87 9.6 9.4 83 3.2 9.4 2.4 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF4407 PF14362.6 CAM45062.1 - 1.3 8.3 6.8 2 7.7 6.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ISG65-75 PF11727.8 CAM45062.1 - 3 7.0 11.6 5.3 6.2 11.6 1.5 1 1 0 1 1 1 0 Invariant surface glycoprotein Med25_SD1 PF11235.8 CAM45062.1 - 3.1 8.1 8.9 1.5 9.1 4.1 2.1 2 0 0 2 2 2 0 Mediator complex subunit 25 synapsin 1 DNA_pol_phi PF04931.13 CAM45064.1 - 0.0017 16.6 35.6 0.0036 15.5 0.0 3.1 3 1 0 3 3 3 2 DNA polymerase phi Glypican PF01153.19 CAM45064.1 - 5.6 5.7 7.5 13 4.5 7.5 1.5 1 0 0 1 1 1 0 Glypican DUF1736 PF08409.11 CAM45065.1 - 1.6e-17 63.2 0.3 4.6e-17 61.8 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_17 PF13431.6 CAM45065.1 - 0.0026 18.0 0.1 0.77 10.3 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF3040 PF11239.8 CAM45065.1 - 0.48 10.7 6.3 8 6.8 1.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Aa_trans PF01490.18 CAM45066.1 - 1.2e-60 205.4 35.7 1.6e-60 205.0 35.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TRAP_alpha PF03896.16 CAM45069.1 - 1.1e-14 54.3 0.1 1.3e-14 54.1 0.1 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Wzt_C PF14524.6 CAM45069.1 - 0.0044 17.1 0.0 0.0079 16.2 0.0 1.4 1 0 0 1 1 1 1 Wzt C-terminal domain zf-Tim10_DDP PF02953.15 CAM45070.1 - 5e-10 38.9 2.9 5.2e-10 38.8 2.9 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Mito_carr PF00153.27 CAM45072.1 - 3.1e-10 39.8 0.5 3.4e-08 33.3 0.1 3.3 3 0 0 3 3 3 1 Mitochondrial carrier protein DUF2618 PF10940.8 CAM45073.1 - 0.29 11.0 0.8 0.62 9.9 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2618) Carn_acyltransf PF00755.20 CAM45074.1 - 2e-89 300.8 0.0 2.5e-89 300.5 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase SEP PF08059.13 CAM45075.1 - 4e-15 56.2 0.0 1.1e-14 54.7 0.0 1.8 1 0 0 1 1 1 1 SEP domain CUE PF02845.16 CAM45075.1 - 0.0054 16.4 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 CUE domain UBA_4 PF14555.6 CAM45075.1 - 0.033 14.0 0.2 0.072 12.9 0.2 1.5 1 0 0 1 1 1 0 UBA-like domain CopC PF04234.12 CAM45076.1 - 0.028 15.5 0.3 0.93 10.6 0.1 2.8 2 0 0 2 2 2 0 CopC domain DUF4061 PF13270.6 CAM45077.1 - 0.011 16.0 2.4 0.015 15.6 1.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4061) Prominin PF05478.11 CAM45077.1 - 0.25 9.2 0.8 0.32 8.9 0.8 1.0 1 0 0 1 1 1 0 Prominin Macoilin PF09726.9 CAM45077.1 - 0.71 8.4 5.6 0.88 8.1 5.6 1.0 1 0 0 1 1 1 0 Macoilin family Peptidase_S46 PF10459.9 CAM45077.1 - 2.7 6.5 5.9 3.5 6.1 5.9 1.0 1 0 0 1 1 1 0 Peptidase S46 Nup54 PF13874.6 CAM45077.1 - 5 7.2 11.8 6.4 6.9 6.1 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 OPA3 PF07047.12 CAM45078.1 - 0.033 14.0 0.6 0.066 13.0 0.6 1.5 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) ZapA PF05164.13 CAM45078.1 - 2.5 8.6 8.3 8.9 6.8 8.2 2.0 1 1 0 1 1 1 0 Cell division protein ZapA DNA_primase_S PF01896.19 CAM45081.1 - 4.5e-41 140.8 0.1 7.2e-41 140.2 0.1 1.3 1 0 0 1 1 1 1 DNA primase small subunit cNMP_binding PF00027.29 CAM45082.2 - 8.8e-06 25.7 0.0 1 9.5 0.0 4.1 4 0 0 4 4 4 2 Cyclic nucleotide-binding domain Ephrin_rec_like PF07699.13 CAM45083.1 - 1e-05 25.2 69.4 0.0002 21.1 4.4 9.2 6 3 3 9 9 9 6 Putative ephrin-receptor like Ribosomal_S19 PF00203.21 CAM45084.1 - 4.2e-28 97.0 0.3 6.1e-28 96.5 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 PmbA_TldD PF01523.16 CAM45084.1 - 0.07 13.0 0.0 0.078 12.8 0.0 1.1 1 0 0 1 1 1 0 Putative modulator of DNA gyrase tRNA_bind PF01588.20 CAM45086.2 - 2.4e-25 88.5 0.0 4.7e-25 87.5 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain Dynamin_N PF00350.23 CAM45087.1 - 3.1e-12 46.9 0.0 2e-11 44.3 0.0 2.0 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 CAM45087.1 - 1.1e-08 35.1 0.0 6e-08 32.8 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CAM45087.1 - 0.00054 19.9 0.4 0.058 13.3 0.4 3.0 2 1 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 CAM45087.1 - 0.0056 16.2 0.0 0.31 10.5 0.0 2.6 2 1 0 2 2 2 1 Ferrous iron transport protein B Roc PF08477.13 CAM45087.1 - 0.0077 16.5 0.0 2 8.7 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 CAM45087.1 - 0.014 14.9 0.1 0.47 10.0 0.0 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 CAM45087.1 - 0.05 14.1 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 CAM45087.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 CAM45087.1 - 0.22 10.6 0.2 6.5 5.8 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit Pkinase PF00069.25 CAM45088.2 - 8.7e-39 133.5 0.0 3.7e-31 108.5 0.0 3.0 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM45088.2 - 7.1e-21 74.6 0.0 1e-17 64.3 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 CAM45088.2 - 8.1e-05 22.1 0.1 0.00014 21.3 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CAM45088.2 - 0.0002 21.3 0.4 0.0002 21.3 0.4 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CAM45088.2 - 0.0064 15.5 0.0 0.0098 14.9 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 CAM45088.2 - 0.029 14.0 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Med26 PF08711.11 CAM45089.1 - 0.00043 20.3 8.8 0.019 15.0 0.0 3.6 3 0 0 3 3 3 3 TFIIS helical bundle-like domain COX5B PF01215.19 CAM45090.1 - 0.0023 17.6 0.0 0.0042 16.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb CxC6 PF18721.1 CAM45090.1 - 0.033 14.5 0.0 0.07 13.4 0.0 1.5 1 0 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases RabGAP-TBC PF00566.18 CAM45091.1 - 9.4e-31 107.1 0.0 1.3e-30 106.7 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain FHA PF00498.26 CAM45092.2 - 1.1e-14 54.6 0.0 1.7e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 FHA domain Rotamase PF00639.21 CAM45092.2 - 2.8e-12 47.5 0.0 7.1e-12 46.1 0.0 1.7 1 1 0 1 1 1 1 PPIC-type PPIASE domain Yop-YscD_cpl PF16697.5 CAM45092.2 - 6.1e-08 32.9 0.0 1.3e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Rotamase_3 PF13616.6 CAM45092.2 - 4.5e-07 30.4 0.0 8.1e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 CAM45092.2 - 0.0083 17.0 0.5 0.048 14.5 0.0 2.3 3 0 0 3 3 3 1 PPIC-type PPIASE domain Kinesin PF00225.23 CAM45094.1 - 1.4e-81 274.0 1.6 1e-46 159.4 0.1 3.1 4 0 0 4 4 4 2 Kinesin motor domain Microtub_bd PF16796.5 CAM45094.1 - 5.2e-21 75.1 0.1 2.6e-20 72.9 0.0 2.3 3 0 0 3 3 3 1 Microtubule binding TPR_MLP1_2 PF07926.12 CAM45094.1 - 0.0023 18.0 17.4 0.0023 18.0 17.4 5.0 4 1 1 5 5 5 1 TPR/MLP1/MLP2-like protein AAA_33 PF13671.6 CAM45094.1 - 0.0035 17.5 0.0 0.025 14.8 0.0 2.5 1 0 0 1 1 1 1 AAA domain GCIP PF13324.6 CAM45094.1 - 0.13 11.9 10.6 0.076 12.6 1.1 2.7 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting Pox_A_type_inc PF04508.12 CAM45094.1 - 3.8 7.5 7.0 59 3.7 0.9 4.3 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Fungal_TACC PF12709.7 CAM45094.1 - 3.9 8.0 21.5 5.4 7.5 4.6 4.5 2 1 2 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF3138 PF11336.8 CAM45094.1 - 8.7 4.8 8.5 0.3 9.7 2.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) AAA PF00004.29 CAM45095.1 - 1.9e-43 148.0 0.0 4e-43 147.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAM45095.1 - 2.4e-10 40.0 0.0 4.9e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CAM45095.1 - 4.4e-06 26.7 0.1 4.3e-05 23.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CAM45095.1 - 1.3e-05 25.5 0.1 0.0054 17.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 CAM45095.1 - 1.9e-05 25.1 0.2 0.00082 19.8 0.0 2.2 1 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 CAM45095.1 - 2e-05 24.8 0.0 4.6e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 CAM45095.1 - 0.00017 20.8 0.0 0.00031 20.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 CAM45095.1 - 0.00025 20.8 0.0 0.00066 19.4 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CAM45095.1 - 0.0021 18.3 0.0 0.0037 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 CAM45095.1 - 0.0053 16.7 0.0 0.35 10.8 0.0 2.4 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 CAM45095.1 - 0.0054 16.3 0.0 0.013 15.0 0.0 1.5 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_33 PF13671.6 CAM45095.1 - 0.0063 16.7 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CAM45095.1 - 0.008 16.2 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CAM45095.1 - 0.0084 16.5 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.21 CAM45095.1 - 0.0087 15.5 0.0 0.023 14.1 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CAM45095.1 - 0.011 15.5 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 CAM45095.1 - 0.011 15.0 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 CAM45095.1 - 0.012 16.2 0.1 0.036 14.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_3 PF07726.11 CAM45095.1 - 0.013 15.4 0.0 0.032 14.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CAM45095.1 - 0.015 15.0 0.1 0.057 13.1 0.1 1.9 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 CAM45095.1 - 0.055 13.2 0.0 0.15 11.8 0.0 1.7 2 0 0 2 2 1 0 Sigma-54 interaction domain NTPase_1 PF03266.15 CAM45095.1 - 0.055 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 NTPase Parvo_NS1 PF01057.17 CAM45095.1 - 0.081 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 CAM45095.1 - 0.1 11.9 0.0 0.25 10.6 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin PhoH PF02562.16 CAM45095.1 - 0.13 11.7 0.2 0.29 10.6 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.6 CAM45095.1 - 0.14 12.5 0.0 0.46 10.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CAM45095.1 - 0.15 11.7 0.0 0.4 10.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 CAM45095.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 CAM45095.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rer1 PF03248.13 CAM45096.1 - 3.9e-16 59.3 0.3 4.6e-16 59.0 0.3 1.0 1 0 0 1 1 1 1 Rer1 family Acyl_CoA_thio PF02551.15 CAM45096.1 - 0.19 11.5 0.1 0.29 11.0 0.1 1.2 1 0 0 1 1 1 0 Acyl-CoA thioesterase TrmO PF01980.16 CAM45097.2 - 6.8e-30 103.7 0.0 1.6e-24 86.4 0.0 2.4 2 0 0 2 2 2 2 tRNA-methyltransferase O PWWP PF00855.17 CAM45097.2 - 0.00014 22.2 0.8 0.00064 20.1 0.7 2.2 2 1 0 2 2 2 1 PWWP domain Acetyltransf_3 PF13302.7 CAM45098.1 - 2.3e-09 38.1 0.1 2.2e-07 31.6 0.0 2.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CAM45098.1 - 8e-08 32.5 0.0 1.3e-05 25.4 0.0 2.6 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 CAM45098.1 - 0.007 16.1 0.4 0.017 14.8 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CAM45098.1 - 0.2 11.7 0.0 0.45 10.5 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein UQ_con PF00179.26 CAM45099.1 - 7.3e-42 142.3 0.0 1e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CAM45099.1 - 0.0004 20.1 0.0 0.00056 19.6 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B AAA PF00004.29 CAM45100.1 - 6.6e-38 130.1 0.4 1.7e-37 128.8 0.0 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CAM45100.1 - 3.7e-17 62.0 0.6 9.5e-17 60.7 0.6 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 CAM45100.1 - 2.7e-12 46.3 0.2 7e-12 45.0 0.2 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CAM45100.1 - 3e-05 24.0 0.1 0.00031 20.8 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CAM45100.1 - 3.3e-05 24.3 3.2 0.0032 17.9 0.0 3.0 2 2 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 CAM45100.1 - 0.00039 20.6 0.1 0.004 17.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CAM45100.1 - 0.00043 20.0 0.0 0.00098 18.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CAM45100.1 - 0.0013 19.0 3.6 0.25 11.6 0.1 3.1 2 1 0 3 3 3 1 AAA domain DUF815 PF05673.13 CAM45100.1 - 0.0015 17.7 0.3 0.0041 16.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 CAM45100.1 - 0.0064 16.7 1.6 0.036 14.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CAM45100.1 - 0.0074 15.7 0.0 0.018 14.4 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 CAM45100.1 - 0.021 14.5 0.0 0.065 13.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CAM45100.1 - 0.051 13.2 1.2 0.21 11.1 0.0 2.4 3 0 0 3 3 3 0 AAA domain ATPase PF06745.13 CAM45100.1 - 0.052 12.9 0.1 0.14 11.4 0.0 1.8 2 0 0 2 2 2 0 KaiC PhoH PF02562.16 CAM45100.1 - 0.058 12.8 0.1 0.36 10.3 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.17 CAM45100.1 - 0.065 13.0 0.5 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 CAM45100.1 - 0.075 12.7 0.0 0.39 10.4 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.6 CAM45100.1 - 0.083 13.4 0.9 0.33 11.5 0.0 2.4 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CAM45100.1 - 0.084 12.1 1.4 0.11 11.7 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin TsaE PF02367.17 CAM45100.1 - 0.12 12.4 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 CAM45100.1 - 0.15 11.9 0.2 0.63 9.9 0.1 2.1 2 0 0 2 2 2 0 NACHT domain Torus PF16131.5 CAM45103.2 - 0.031 15.0 1.5 0.093 13.4 1.5 1.8 1 0 0 1 1 1 0 Torus domain Prefoldin PF02996.17 CAM45104.1 - 2.1e-18 66.4 4.0 3e-18 65.9 2.9 1.6 1 1 1 2 2 2 1 Prefoldin subunit TENA_THI-4 PF03070.16 CAM45104.1 - 0.00067 19.5 0.8 0.00088 19.1 0.8 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Prefoldin_2 PF01920.20 CAM45104.1 - 0.0071 16.3 2.0 0.081 12.9 1.7 2.1 2 0 0 2 2 2 1 Prefoldin subunit Sec20 PF03908.13 CAM45104.1 - 0.033 14.1 2.0 7.6 6.5 0.0 2.5 2 1 1 3 3 3 0 Sec20 DUF1454 PF07305.12 CAM45105.1 - 0.055 12.9 0.0 0.074 12.5 0.0 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1454) Vpu PF00558.19 CAM45106.1 - 0.051 13.3 0.3 0.051 13.3 0.3 1.7 2 0 0 2 2 2 0 Vpu protein YbaB_DNA_bd PF02575.16 CAM45108.1 - 0.0001 22.4 0.0 0.00019 21.6 0.0 1.4 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family HIF-1 PF11413.8 CAM45108.1 - 0.019 14.4 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Hypoxia-inducible factor-1 MMR_HSR1 PF01926.23 CAM45109.1 - 1.6e-16 60.4 0.0 3.2e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CAM45109.1 - 3.4e-08 33.7 0.0 3.9e-06 27.0 0.1 2.4 1 1 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 CAM45109.1 - 5e-05 23.3 0.0 0.0052 16.7 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 CAM45109.1 - 0.00067 19.0 0.0 0.0027 17.1 0.0 1.9 1 1 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 CAM45109.1 - 0.00087 18.9 0.0 0.0075 15.8 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Septin PF00735.18 CAM45109.1 - 0.0024 17.2 0.0 0.0049 16.2 0.0 1.5 1 1 0 1 1 1 1 Septin cobW PF02492.19 CAM45109.1 - 0.013 15.1 0.0 0.91 9.1 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 CAM45109.1 - 0.036 14.3 0.0 0.1 12.8 0.0 1.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Guanylate_kin PF00625.21 CAM45109.1 - 0.042 13.5 0.0 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 Guanylate kinase ABC_tran PF00005.27 CAM45109.1 - 0.052 14.1 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter FeoB_N PF02421.18 CAM45109.1 - 0.099 12.2 0.0 0.25 10.9 0.0 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B GAS PF13851.6 CAM45110.1 - 0.18 11.2 34.6 0.84 9.0 3.6 3.6 2 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding ApoO PF09769.9 CAM45110.1 - 0.86 9.6 2.5 7.9 6.5 0.2 2.5 2 0 0 2 2 2 0 Apolipoprotein O ATG16 PF08614.11 CAM45110.1 - 1.6 8.9 28.5 4.9 7.3 1.0 2.6 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) PRKG1_interact PF15898.5 CAM45110.1 - 2.8 8.9 29.1 1.3 9.9 7.3 3.8 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain Torus PF16131.5 CAM45113.1 - 3.3e-05 24.5 0.3 0.32 11.7 0.1 2.6 2 0 0 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 CAM45113.1 - 4.4e-05 23.4 12.1 0.00083 19.3 1.8 2.6 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 CAM45113.1 - 0.033 14.1 0.6 0.033 14.1 0.6 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CAM45113.1 - 6.9 6.6 8.5 1.7 8.5 1.4 2.5 2 0 0 2 2 2 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CAM45114.2 - 0.0031 17.5 10.6 0.24 11.5 1.4 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 CAM45114.2 - 0.029 14.3 0.8 0.029 14.3 0.8 3.3 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CAM45114.2 - 0.15 11.9 10.4 0.83 9.5 2.0 2.4 2 0 0 2 2 2 0 CCCH-type zinc finger NAD_binding_1 PF00175.21 CAM45116.1 - 2.4e-27 95.7 0.0 3.6e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CAM45116.1 - 1.4e-24 86.3 0.0 2.4e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CAM45116.1 - 5.7e-05 23.3 0.2 0.00081 19.5 0.0 2.2 1 1 0 2 2 2 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 CAM45117.1 - 2.4e-26 92.5 0.0 3.4e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CAM45117.1 - 1.4e-20 73.5 0.0 2.5e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CAM45117.1 - 5.4e-07 29.9 0.0 5.2e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain SUI1 PF01253.22 CAM45119.2 - 2.8e-17 63.0 0.0 1.7e-16 60.5 0.0 2.4 2 0 0 2 2 2 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 CAM45119.2 - 9.7e-08 32.6 0.9 5.5e-07 30.2 0.3 2.5 2 0 0 2 2 2 1 Pre-PUA-like domain PUA PF01472.20 CAM45119.2 - 0.011 15.6 0.0 0.042 13.8 0.0 2.0 1 0 0 1 1 1 0 PUA domain zinc_ribbon_10 PF10058.9 CAM45120.1 - 0.00015 21.5 10.1 0.001 18.7 0.1 3.4 3 1 0 3 3 3 2 Predicted integral membrane zinc-ribbon metal-binding protein Mu-like_Com PF10122.9 CAM45120.1 - 0.017 14.6 11.5 0.17 11.4 0.1 3.2 3 1 1 4 4 4 0 Mu-like prophage protein Com zf-Sec23_Sec24 PF04810.15 CAM45120.1 - 0.16 12.0 13.1 8 6.6 0.2 4.2 4 0 0 4 4 4 0 Sec23/Sec24 zinc finger Cytochrom_c3_2 PF14537.6 CAM45120.1 - 0.19 12.2 11.8 0.21 12.1 7.8 2.5 1 1 1 2 2 2 0 Cytochrome c3 Cytochrom_CIII PF02085.16 CAM45120.1 - 0.21 11.9 9.3 0.05 14.0 5.5 1.8 1 1 0 1 1 1 0 Class III cytochrome C family VATC PF18716.1 CAM45120.1 - 0.3 11.0 0.2 0.3 11.0 0.2 3.0 3 0 0 3 3 3 0 Vms1-associating treble clef domain CCDC50_N PF15295.6 CAM45120.1 - 0.5 10.5 4.1 2.4 8.3 4.1 2.0 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus PHD_4 PF16866.5 CAM45120.1 - 1.7 8.8 11.2 0.076 13.1 2.4 2.8 2 1 0 3 3 3 0 PHD-finger Zn_Tnp_IS1595 PF12760.7 CAM45120.1 - 5.6 7.0 8.6 0.52 10.3 0.7 3.1 4 0 0 4 4 4 0 Transposase zinc-ribbon domain Rubredoxin_2 PF18073.1 CAM45120.1 - 8.9 6.1 13.8 31 4.4 0.5 4.9 5 0 0 5 5 5 0 Rubredoxin metal binding domain Pkinase PF00069.25 CAM45121.2 - 2e-63 214.3 0.0 2.5e-63 213.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM45121.2 - 4.8e-32 111.3 0.0 6.4e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM45121.2 - 8e-05 22.1 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Fanconi_A_N PF15865.5 CAM45121.2 - 0.13 11.7 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Fanconi anaemia group A protein N terminus Ribosomal_L22 PF00237.19 CAM45122.1 - 6.8e-14 52.0 0.0 1e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e IQ PF00612.27 CAM45126.2 - 0.59 10.1 4.8 2 8.4 4.8 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif Prp18 PF02840.15 CAM45127.1 - 7.4e-12 45.5 0.1 1.7e-11 44.4 0.1 1.6 1 0 0 1 1 1 1 Prp18 domain Arrestin_N PF00339.29 CAM45128.1 - 2.3e-10 40.7 0.0 3.7e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 CAM45128.1 - 0.0027 18.1 0.0 0.61 10.5 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 CAM45128.1 - 0.025 14.3 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like EF-hand_6 PF13405.6 CAM45129.2 - 2.1e-10 39.7 0.5 0.039 13.9 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 CAM45129.2 - 1.9e-08 34.6 0.4 0.0024 18.3 0.1 4.0 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_8 PF13833.6 CAM45129.2 - 5.6e-05 22.9 0.1 0.45 10.4 0.1 3.7 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 CAM45129.2 - 6.5e-05 22.2 0.1 1.8 8.3 0.0 4.0 4 0 0 4 4 4 2 EF hand DUF2793 PF10983.8 CAM45130.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2793) AAA PF00004.29 CAM45131.1 - 1.9e-13 51.0 0.0 1.9e-07 31.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CAM45131.1 - 3.1e-05 24.0 0.0 6.7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Pkinase PF00069.25 CAM45132.1 - 2.8e-62 210.5 0.0 3.3e-62 210.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM45132.1 - 3.9e-42 144.3 0.0 4.8e-42 144.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM45132.1 - 1.1e-07 31.5 0.0 2e-07 30.7 0.0 1.4 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CAM45132.1 - 0.00097 18.5 0.1 0.019 14.3 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CAM45132.1 - 0.0012 17.8 0.0 0.0018 17.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CAM45132.1 - 0.052 13.5 0.0 0.092 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CAM45132.1 - 0.16 10.9 0.0 0.34 9.8 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain Kinesin PF00225.23 CAM45133.2 - 1.7e-91 306.6 0.0 5.7e-91 304.9 0.0 1.9 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CAM45133.2 - 1.1e-11 44.9 1.3 1.3e-06 28.5 0.0 3.9 4 0 0 4 4 4 2 Microtubule binding TPR_MLP1_2 PF07926.12 CAM45133.2 - 9.8e-05 22.4 16.7 9.8e-05 22.4 16.7 7.7 3 2 3 7 7 7 2 TPR/MLP1/MLP2-like protein KELK PF15796.5 CAM45133.2 - 0.004 17.6 2.8 0.004 17.6 2.8 8.5 7 2 1 8 8 8 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase NPR2 PF06218.11 CAM45134.2 - 0.001 17.9 0.0 0.011 14.5 0.0 2.0 2 0 0 2 2 2 2 Nitrogen permease regulator 2 WD40 PF00400.32 CAM45135.1 - 0.0086 16.9 1.3 0.16 12.9 0.0 3.0 3 0 0 3 3 3 1 WD domain, G-beta repeat MRJP PF03022.16 CAM45135.1 - 0.021 14.2 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Major royal jelly protein UAA PF08449.11 CAM45139.1 - 1.1e-31 110.2 9.9 1.3e-31 109.9 7.7 2.0 2 1 0 2 2 2 1 UAA transporter family EamA PF00892.20 CAM45139.1 - 0.029 14.5 17.2 0.36 11.0 0.1 3.8 3 1 0 3 3 3 0 EamA-like transporter family Kelch_5 PF13854.6 CAM45142.1 - 9e-21 73.4 3.2 2.6e-05 24.1 0.1 7.1 6 1 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 CAM45142.1 - 5.3e-20 71.2 13.0 3.4e-05 23.8 0.0 6.8 5 2 1 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 CAM45142.1 - 2.2e-16 59.1 4.4 9.1e-06 25.5 0.1 6.5 7 0 0 7 7 7 3 Kelch motif Kelch_3 PF13415.6 CAM45142.1 - 3.7e-16 59.0 28.2 0.00018 21.7 0.1 8.2 8 1 0 8 8 8 4 Galactose oxidase, central domain Kelch_6 PF13964.6 CAM45142.1 - 3.5e-15 55.7 1.8 0.056 13.8 0.1 6.6 6 1 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 CAM45142.1 - 1.8e-14 53.0 4.5 0.005 16.4 0.1 7.1 7 0 0 7 7 7 4 Kelch motif BTB PF00651.31 CAM45142.1 - 0.0014 18.8 0.1 0.018 15.3 0.0 2.6 3 0 0 3 3 3 1 BTB/POZ domain MFS_1 PF07690.16 CAM45145.1 - 9.9e-22 77.3 27.9 9.9e-22 77.3 27.9 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 CAM45145.1 - 1.8e-15 56.3 16.1 6.5e-10 37.9 2.0 3.8 2 2 2 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 CAM45145.1 - 3.4e-14 52.6 6.5 3.4e-14 52.6 6.5 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 CAM45145.1 - 3.7e-07 29.8 3.9 3.7e-07 29.8 3.9 3.1 2 1 1 3 3 3 2 Uncharacterised MFS-type transporter YbfB LSM PF01423.22 CAM45146.1 - 9.2e-13 47.7 0.1 1.1e-12 47.4 0.1 1.1 1 0 0 1 1 1 1 LSM domain SP2 PF03014.14 CAM45146.1 - 0.003 16.0 0.1 0.003 16.0 0.1 1.0 1 0 0 1 1 1 1 Structural protein 2 Med20 PF08612.11 CAM45146.1 - 0.035 13.5 0.0 0.036 13.4 0.0 1.1 1 0 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex SM-ATX PF14438.6 CAM45146.1 - 0.054 13.6 0.0 0.086 13.0 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain Tmpp129 PF10272.9 CAM45147.2 - 0.57 9.4 4.3 0.95 8.7 4.3 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor SUIM_assoc PF16619.5 CAM45147.2 - 2.1 8.5 0.0 2.1 8.5 0.0 6.2 7 1 0 7 7 7 0 Unstructured region C-term to UIM in Ataxin3 CRAL_TRIO PF00650.20 CAM45150.2 - 3.7e-14 52.8 0.0 2.1e-13 50.3 0.0 2.2 2 1 0 2 2 2 1 CRAL/TRIO domain zf-C3HC4_3 PF13920.6 CAM45151.2 - 6.4e-08 32.3 11.1 6.4e-08 32.3 11.1 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CAM45151.2 - 0.85 9.5 10.3 2.1 8.3 10.3 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CAM45151.2 - 4.4 7.3 14.0 3.5 7.7 10.7 2.3 2 0 0 2 2 2 0 zinc-RING finger domain AAA_6 PF12774.7 CAM45153.2 - 1e-130 435.5 0.1 2.4e-127 424.5 0.0 4.3 3 1 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CAM45153.2 - 3.5e-84 283.2 0.0 1.1e-83 281.5 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 CAM45153.2 - 2.8e-62 209.7 0.0 1.1e-60 204.6 0.0 2.6 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 CAM45153.2 - 8.5e-60 202.3 0.0 2.8e-37 128.5 0.0 2.8 2 0 0 2 2 2 2 P-loop containing dynein motor region D4 AAA_7 PF12775.7 CAM45153.2 - 8.5e-45 152.5 0.2 1.4e-37 129.0 0.0 4.7 5 0 0 5 5 4 2 P-loop containing dynein motor region MT PF12777.7 CAM45153.2 - 1.6e-35 122.8 0.8 2.6e-35 122.1 0.8 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 CAM45153.2 - 8e-29 100.4 2.4 3.6e-10 40.0 0.1 7.2 5 2 0 5 5 5 4 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 CAM45153.2 - 4.6e-23 81.6 0.0 9.7e-22 77.3 0.0 3.2 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_C PF18199.1 CAM45153.2 - 6.8e-22 78.1 0.0 1.8e-21 76.6 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 CAM45153.2 - 3.6e-21 75.7 0.0 7.9e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 CAM45153.2 - 1.4e-19 70.8 0.0 3.6e-06 27.4 0.0 5.1 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CAM45153.2 - 2.7e-15 56.8 7.1 7.7e-06 26.2 0.0 6.9 6 0 0 6 6 6 2 AAA domain AAA_16 PF13191.6 CAM45153.2 - 3e-11 44.0 12.4 0.067 13.6 0.0 7.7 7 0 0 7 7 4 4 AAA ATPase domain AAA_33 PF13671.6 CAM45153.2 - 1.6e-07 31.6 1.7 0.18 12.0 0.0 5.3 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.6 CAM45153.2 - 1e-06 29.3 0.1 9.1 6.8 0.0 5.6 5 0 0 5 5 4 0 AAA domain AAA_24 PF13479.6 CAM45153.2 - 1.2e-06 28.4 0.1 2 8.1 0.0 4.4 4 0 0 4 4 4 2 AAA domain AAA_25 PF13481.6 CAM45153.2 - 1.8e-06 27.7 0.3 0.11 12.1 0.0 4.1 3 0 0 3 3 3 2 AAA domain T2SSE PF00437.20 CAM45153.2 - 6e-06 25.5 0.0 0.42 9.6 0.0 4.3 4 0 0 4 4 4 1 Type II/IV secretion system protein IstB_IS21 PF01695.17 CAM45153.2 - 1.7e-05 24.7 2.1 0.057 13.1 0.0 4.4 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_30 PF13604.6 CAM45153.2 - 2.7e-05 24.0 5.7 0.46 10.2 0.2 4.5 4 0 0 4 4 4 2 AAA domain AAA_lid_1 PF17857.1 CAM45153.2 - 7.6e-05 22.9 0.0 0.00031 20.9 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain ABC_tran PF00005.27 CAM45153.2 - 9.2e-05 23.0 0.2 0.36 11.3 0.0 4.5 4 0 0 4 4 3 1 ABC transporter Sigma54_activat PF00158.26 CAM45153.2 - 0.00018 21.3 0.0 0.24 11.1 0.0 3.3 3 0 0 3 3 3 1 Sigma-54 interaction domain RNA_helicase PF00910.22 CAM45153.2 - 0.00031 21.1 0.2 4.9 7.6 0.0 4.7 4 0 0 4 4 4 0 RNA helicase AAA_19 PF13245.6 CAM45153.2 - 0.00042 20.7 6.2 2.9 8.2 0.0 5.3 5 0 0 5 5 4 1 AAA domain FtsK_SpoIIIE PF01580.18 CAM45153.2 - 0.0012 18.3 5.7 0.37 10.1 0.0 4.1 5 0 0 5 5 3 2 FtsK/SpoIIIE family AAA_29 PF13555.6 CAM45153.2 - 0.0019 17.9 4.2 1.3 8.8 0.0 4.5 4 0 0 4 4 4 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CAM45153.2 - 0.0025 17.7 0.0 15 5.4 0.0 3.8 3 0 0 3 3 3 0 RsgA GTPase AAA_28 PF13521.6 CAM45153.2 - 0.004 17.4 0.6 48 4.1 0.1 5.0 4 0 0 4 4 4 0 AAA domain RuvB_N PF05496.12 CAM45153.2 - 0.0041 16.9 0.6 1.4 8.6 0.0 3.7 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 CAM45153.2 - 0.0064 15.9 7.7 0.24 10.8 0.0 4.0 4 0 0 4 4 3 1 Magnesium chelatase, subunit ChlI Peripla_BP_3 PF13377.6 CAM45153.2 - 0.026 14.8 0.1 0.15 12.3 0.1 2.5 2 0 0 2 2 1 0 Periplasmic binding protein-like domain Dynein_AAA_lid PF17852.1 CAM45153.2 - 0.032 14.3 0.1 0.11 12.6 0.1 1.9 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain POT1PC PF16686.5 CAM45153.2 - 0.043 13.7 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 ssDNA-binding domain of telomere protection protein AAA_11 PF13086.6 CAM45153.2 - 0.058 13.2 12.0 1.9 8.2 0.0 4.7 5 0 0 5 5 4 0 AAA domain TrwB_AAD_bind PF10412.9 CAM45153.2 - 0.062 12.2 2.3 2.8 6.8 0.3 3.2 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain MCR_alpha PF02249.17 CAM45153.2 - 0.069 13.6 1.3 0.71 10.3 0.5 3.0 2 0 0 2 2 2 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain SRP54 PF00448.22 CAM45153.2 - 0.082 12.5 2.3 3.1 7.4 0.2 3.6 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain Rad17 PF03215.15 CAM45153.2 - 0.11 12.4 0.1 37 4.2 0.0 3.8 4 0 0 4 4 4 0 Rad17 P-loop domain NB-ARC PF00931.22 CAM45153.2 - 0.13 11.4 0.4 3.3 6.8 0.1 3.0 3 0 0 3 3 3 0 NB-ARC domain PhoH PF02562.16 CAM45153.2 - 0.3 10.5 7.9 0.11 11.9 0.1 3.3 4 0 0 4 4 3 0 PhoH-like protein CbiA PF01656.23 CAM45153.2 - 0.3 11.1 1.8 33 4.6 0.1 3.9 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.12 CAM45153.2 - 0.83 9.5 4.4 1e+02 2.8 0.1 4.6 4 0 0 4 4 4 0 NACHT domain Noelin-1 PF12308.8 CAM45153.2 - 2 8.4 5.3 77 3.4 0.4 4.3 3 0 0 3 3 3 0 Neurogenesis glycoprotein Lactamase_B_2 PF12706.7 CAM45154.1 - 8.4e-13 48.3 0.0 1.3e-08 34.6 0.1 2.4 1 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CAM45154.1 - 5.3e-05 23.3 0.4 0.00014 21.9 0.2 1.8 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily Adap_comp_sub PF00928.21 CAM45157.1 - 1.2e-82 277.3 0.1 1.5e-82 277.0 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CAM45157.1 - 0.0055 16.6 0.3 0.0097 15.8 0.3 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PhetRS_B1 PF18262.1 CAM45157.1 - 0.049 13.9 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain Pkinase PF00069.25 CAM45159.1 - 6e-14 52.0 0.0 8.4e-07 28.6 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM45159.1 - 0.001 18.4 0.0 0.35 10.1 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase VanW PF04294.13 CAM45159.1 - 0.019 14.6 0.1 0.056 13.1 0.1 1.8 1 1 0 1 1 1 0 VanW like protein Pkinase PF00069.25 CAM45165.1 - 1.6e-22 80.1 0.0 1.4e-17 63.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM45165.1 - 3.6e-08 33.0 0.0 3.6e-07 29.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase DUF4134 PF13572.6 CAM45165.1 - 0.23 11.7 0.2 0.47 10.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4134) ChaC PF04752.12 CAM45166.1 - 2.5e-42 145.0 0.0 3.6e-41 141.2 0.0 2.0 1 1 0 1 1 1 1 ChaC-like protein DUF4732 PF15876.5 CAM45166.1 - 0.2 11.7 0.0 0.3 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4732) SHS2_Rpb7-N PF03876.17 CAM45170.1 - 0.098 13.0 0.0 20 5.6 0.0 2.6 2 0 0 2 2 2 0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 GTP_EFTU PF00009.27 CAM45172.1 - 1.4e-33 116.1 3.0 7.7e-32 110.4 3.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CAM45172.1 - 5.9e-10 39.2 0.1 1.2e-09 38.2 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF-2 PF11987.8 CAM45172.1 - 0.0002 21.4 0.0 0.00054 20.0 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 SRPRB PF09439.10 CAM45172.1 - 0.00022 20.7 0.0 0.00046 19.7 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 CAM45172.1 - 0.00036 20.1 0.0 0.0007 19.2 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.9 CAM45172.1 - 0.00037 20.2 0.0 0.0012 18.7 0.0 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 CAM45172.1 - 0.0014 18.7 2.4 0.82 9.7 0.0 3.2 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 CAM45172.1 - 0.0051 16.7 0.0 4.8 7.1 0.0 2.5 1 1 1 2 2 2 2 RsgA GTPase Roc PF08477.13 CAM45172.1 - 0.011 15.9 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase WD40 PF00400.32 CAM45173.1 - 5.9e-13 49.1 15.0 0.0041 17.9 0.2 6.9 6 1 0 6 6 6 6 WD domain, G-beta repeat MORN PF02493.20 CAM45176.1 - 3.7e-07 29.6 11.7 0.056 13.4 1.4 3.5 3 0 0 3 3 3 3 MORN repeat CPSase_L_D2 PF02786.17 CAM45177.1 - 0.023 14.2 0.1 0.041 13.4 0.1 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Ribonuc_red_sm PF00268.21 CAM45178.1 - 5e-111 370.6 0.1 6.1e-111 370.3 0.1 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain NMT PF01233.19 CAM45178.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Atg8 PF02991.16 CAM45179.1 - 1.4e-11 44.5 0.0 8e-11 42.1 0.0 1.9 2 0 0 2 2 2 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 CAM45179.1 - 0.00041 20.7 0.0 0.0006 20.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Anillin_N PF16018.5 CAM45181.1 - 4 8.1 5.6 1.2 9.8 0.1 3.0 3 0 0 3 3 3 0 Anillin N-terminus COMP PF11598.8 CAM45185.2 - 0.25 11.9 0.0 0.25 11.9 0.0 4.2 5 0 0 5 5 5 0 Cartilage oligomeric matrix protein DUF2937 PF11157.8 CAM45185.2 - 2.8 7.7 8.8 0.47 10.1 1.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Methyltransf_28 PF02636.17 CAM45186.1 - 2e-40 139.1 0.0 2.8e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_25 PF13649.6 CAM45186.1 - 0.0042 17.8 0.0 0.01 16.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAM45186.1 - 0.0046 16.8 0.0 0.0077 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 CAM45186.1 - 0.0059 15.7 0.0 0.0097 15.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 CAM45186.1 - 0.013 16.2 0.0 0.025 15.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_C62 PF12380.8 CAM45186.1 - 0.14 11.2 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Gill-associated viral 3C-like peptidase DHHC PF01529.20 CAM45187.1 - 4.1e-32 111.1 8.9 4.1e-32 111.1 8.9 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF2569 PF10754.9 CAM45187.1 - 0.58 10.6 6.3 0.39 11.2 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) DUF3949 PF13133.6 CAM45187.1 - 1.6 9.3 3.3 0.61 10.6 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3949) polyprenyl_synt PF00348.17 CAM45189.1 - 8e-75 251.2 0.7 9.8e-75 250.9 0.7 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Cep57_CLD PF14073.6 CAM45190.1 - 0.015 15.4 10.1 0.015 15.4 10.1 4.9 2 2 2 4 4 4 0 Centrosome localisation domain of Cep57 YhzD PF14120.6 CAM45190.1 - 0.086 13.0 0.8 0.38 10.9 0.8 2.2 1 0 0 1 1 1 0 YhzD-like protein Ribosomal_L28e PF01778.17 CAM45192.1 - 1.5e-28 99.8 0.2 3.2e-28 98.8 0.0 1.5 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 CAM45192.1 - 1.7e-15 57.4 18.9 1.7e-15 57.4 18.9 2.0 1 1 0 1 1 1 1 Mak16 protein C-terminal region Gag_p24 PF00607.20 CAM45192.1 - 0.051 13.4 0.2 0.098 12.5 0.1 1.5 1 1 1 2 2 2 0 gag gene protein p24 (core nucleocapsid protein) CDC45 PF02724.14 CAM45192.1 - 0.44 8.8 12.7 0.21 9.8 10.9 1.3 1 1 0 1 1 1 0 CDC45-like protein UCH PF00443.29 CAM45192.1 - 0.5 9.8 1.7 0.69 9.4 1.7 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase YqfQ PF14181.6 CAM45192.1 - 7.2 6.8 8.8 2.7 8.2 4.1 2.0 2 0 0 2 2 2 0 YqfQ-like protein MORN PF02493.20 CAM45194.2 - 7.8e-47 154.5 82.0 6.1e-05 22.7 0.2 13.0 13 0 0 13 13 13 12 MORN repeat EF-hand_1 PF00036.32 CAM45196.1 - 8.4e-26 87.6 7.5 2.8e-08 32.7 0.4 4.1 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 CAM45196.1 - 1.2e-22 80.1 1.2 4.8e-11 42.9 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CAM45196.1 - 1.8e-19 67.9 4.4 4.9e-07 29.2 0.1 4.0 3 1 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 CAM45196.1 - 1e-17 63.7 6.7 6.9e-10 38.6 0.4 3.9 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 CAM45196.1 - 1.5e-17 62.2 6.8 1.7e-05 24.1 0.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 CAM45196.1 - 1.4e-07 31.8 0.0 1.6e-06 28.3 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 CAM45196.1 - 2.7e-07 30.5 2.4 0.051 13.5 0.9 3.1 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.10 CAM45196.1 - 0.02 15.0 0.1 9.6 6.4 0.0 2.8 2 1 0 2 2 2 0 Ca2+ insensitive EF hand DUF3911 PF13050.6 CAM45196.1 - 0.094 12.8 0.2 0.2 11.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3911) SPARC_Ca_bdg PF10591.9 CAM45196.1 - 0.096 13.0 0.0 0.29 11.5 0.0 1.8 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region MIP PF00230.20 CAM45197.1 - 1.1e-22 80.9 17.6 1.1e-21 77.6 17.3 2.2 1 1 1 2 2 2 2 Major intrinsic protein FKBP_C PF00254.28 CAM45198.1 - 6e-29 100.2 0.0 1.2e-28 99.3 0.0 1.5 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pro_isomerase PF00160.21 CAM45201.1 - 6.9e-35 120.7 0.0 8.8e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD EF-hand_8 PF13833.6 CAM45202.1 - 5.9e-07 29.2 0.1 3.4e-06 26.8 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 CAM45202.1 - 5.4e-05 23.6 0.0 0.0074 16.7 0.0 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CAM45202.1 - 0.011 15.6 0.0 1.5 8.9 0.0 3.2 3 1 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.32 CAM45202.1 - 0.02 14.4 0.0 7.3 6.4 0.0 3.3 3 1 0 3 3 3 0 EF hand TPR_2 PF07719.17 CAM45203.1 - 0.0031 17.5 0.6 0.93 9.8 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CAM45203.1 - 0.087 13.1 2.9 2.2 8.6 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat RE_MjaI PF09568.10 CAM45203.1 - 0.14 11.9 0.1 0.34 10.7 0.0 1.5 2 0 0 2 2 2 0 MjaI restriction endonuclease MAM33 PF02330.16 CAM45205.1 - 4.6e-21 75.8 0.2 5e-19 69.1 0.2 2.4 1 1 0 1 1 1 1 Mitochondrial glycoprotein RVT_1 PF00078.27 CAM45207.1 - 7.6e-06 25.6 0.0 9.8e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RE_MjaI PF09568.10 CAM45208.1 - 0.084 12.7 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 MjaI restriction endonuclease Metallophos PF00149.28 CAM45210.1 - 4.2e-14 53.5 0.1 5.7e-14 53.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.11 CAM45210.1 - 0.064 11.5 0.1 4 5.6 0.0 2.8 3 0 0 3 3 3 0 Firmicute fructose-1,6-bisphosphatase Ribosomal_L14e PF01929.17 CAM45213.1 - 1.7e-18 66.9 1.2 1.7e-18 66.9 1.2 2.2 2 1 0 2 2 2 1 Ribosomal protein L14 KOW PF00467.29 CAM45213.1 - 8.6e-05 22.3 1.1 0.00018 21.4 1.1 1.5 1 0 0 1 1 1 1 KOW motif CoaE PF01121.20 CAM45215.1 - 3.6e-42 144.1 0.0 6.9e-42 143.1 0.0 1.4 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 CAM45215.1 - 0.00013 22.5 0.3 0.0072 16.9 0.3 2.7 1 1 1 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.6 CAM45215.1 - 0.0084 16.3 1.0 2.3 8.3 0.1 2.4 2 1 0 2 2 2 2 Cytidylate kinase-like family SKI PF01202.22 CAM45215.1 - 0.091 12.9 0.0 0.37 10.9 0.0 1.9 2 0 0 2 2 2 0 Shikimate kinase AAA_33 PF13671.6 CAM45215.1 - 0.14 12.4 0.0 1.8 8.7 0.0 2.5 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 CAM45215.1 - 0.16 12.4 0.0 1.3 9.4 0.0 2.2 2 1 0 2 2 2 0 AAA domain tRNA-synt_2c PF01411.19 CAM45216.2 - 3.8e-192 639.6 0.0 5e-192 639.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 CAM45216.2 - 1.2e-10 41.3 0.0 3.1e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 CAM45216.2 - 0.00018 21.9 4.3 0.00022 21.7 1.3 2.6 1 1 1 2 2 2 1 DHHA1 domain FliMN_C PF01052.20 CAM45217.1 - 0.017 15.1 0.0 0.043 13.8 0.0 1.6 1 0 0 1 1 1 0 Type III flagellar switch regulator (C-ring) FliN C-term Ribosomal_L14e PF01929.17 CAM45218.1 - 1.7e-18 66.9 1.2 1.7e-18 66.9 1.2 2.2 2 1 0 2 2 2 1 Ribosomal protein L14 KOW PF00467.29 CAM45218.1 - 8.6e-05 22.3 1.1 0.00018 21.4 1.1 1.5 1 0 0 1 1 1 1 KOW motif RNase_PH PF01138.21 CAM45222.1 - 7.6e-09 36.2 0.0 1.8e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CAM45222.1 - 0.00018 21.5 0.2 0.00042 20.3 0.2 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 NAD_binding_5 PF07994.12 CAM45222.1 - 0.069 12.5 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase Metallophos PF00149.28 CAM45225.1 - 1.3e-10 42.1 0.0 2.1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CAM45225.1 - 1e-05 25.8 0.0 1.9e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ASH PF15780.5 CAM45228.2 - 5.7e-38 129.1 27.4 1e-05 25.6 0.1 16.5 16 0 0 16 16 16 12 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 CAM45228.2 - 1.8e-10 41.0 2.0 1 9.7 0.2 9.5 10 0 0 10 10 10 3 Transmembrane protein 131-like Motile_Sperm PF00635.26 CAM45228.2 - 4.8e-10 39.3 0.0 1.9 8.4 0.0 8.5 10 0 0 10 10 10 3 MSP (Major sperm protein) domain PapD-like PF14874.6 CAM45228.2 - 1.1e-05 25.5 10.2 0.0032 17.6 0.1 7.3 6 2 1 7 7 7 1 Flagellar-associated PapD-like CAF1 PF04857.20 CAM45230.1 - 2.6e-22 79.4 2.6 4.3e-11 42.6 0.1 2.5 1 1 1 2 2 2 2 CAF1 family ribonuclease cobW PF02492.19 CAM45232.1 - 2.8e-27 95.4 0.1 3.9e-27 95.0 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 CAM45232.1 - 0.012 15.9 0.0 0.032 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain CobW_C PF07683.14 CAM45232.1 - 0.014 15.3 0.0 0.042 13.8 0.0 1.7 1 1 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain ABC_tran PF00005.27 CAM45232.1 - 0.023 15.2 0.0 0.038 14.5 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 CAM45232.1 - 0.038 14.1 0.0 0.076 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CAM45232.1 - 0.076 13.4 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain SRP54 PF00448.22 CAM45232.1 - 0.082 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_7 PF12775.7 CAM45232.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region CBP_BcsQ PF06564.12 CAM45232.1 - 0.13 11.7 0.0 12 5.3 0.0 2.2 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ TrwB_AAD_bind PF10412.9 CAM45232.1 - 0.14 11.0 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain MobB PF03205.14 CAM45232.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B T2SSE PF00437.20 CAM45232.1 - 0.17 10.9 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RIIa PF02197.17 CAM45234.1 - 0.0033 17.1 0.1 0.013 15.2 0.1 2.0 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit RINT1_TIP1 PF04437.13 CAM45234.1 - 0.0089 15.0 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 RINT-1 / TIP-1 family PI-PLC-X PF00388.19 CAM45237.1 - 1.9e-58 196.2 0.0 3.8e-58 195.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 CAM45237.1 - 1.4e-32 112.4 0.0 4.8e-32 110.7 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 CAM45237.1 - 1.5e-06 28.5 0.0 3e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.6 CAM45237.1 - 5.1e-06 26.8 0.7 2.1e-05 24.8 0.1 2.5 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CAM45237.1 - 0.00017 20.9 0.0 0.0019 17.6 0.0 2.8 2 1 1 3 3 3 1 EF hand EF-hand_6 PF13405.6 CAM45237.1 - 0.0027 17.5 0.0 0.094 12.7 0.0 3.2 2 1 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 CAM45237.1 - 0.18 11.4 0.0 0.51 9.9 0.0 1.8 1 0 0 1 1 1 0 EF hand COMP PF11598.8 CAM45238.1 - 3.5e-73 241.9 160.7 0.021 15.3 0.0 42.1 27 18 15 42 42 42 29 Cartilage oligomeric matrix protein DUF4201 PF13870.6 CAM45238.1 - 6.5e-69 231.2 51.5 2.5e-05 24.1 0.2 16.8 9 6 9 18 18 18 17 Domain of unknown function (DUF4201) TMF_DNA_bd PF12329.8 CAM45238.1 - 1.1e-68 227.1 93.5 0.0027 17.7 1.0 25.7 26 0 0 26 26 26 18 TATA element modulatory factor 1 DNA binding Fez1 PF06818.15 CAM45238.1 - 1.6e-31 110.3 135.0 0.00031 21.3 6.6 13.1 1 1 14 15 15 15 15 Fez1 DUF641 PF04859.12 CAM45238.1 - 6.1e-29 100.9 150.6 0.64 10.4 1.6 25.8 2 2 24 26 26 26 18 Plant protein of unknown function (DUF641) ATG16 PF08614.11 CAM45238.1 - 2.1e-28 100.0 211.5 0.0042 17.3 14.4 13.1 1 1 12 14 14 14 13 Autophagy protein 16 (ATG16) Fib_alpha PF08702.10 CAM45238.1 - 1.6e-20 73.8 71.4 0.48 10.6 0.6 21.7 11 8 5 21 21 21 4 Fibrinogen alpha/beta chain family HIP1_clath_bdg PF16515.5 CAM45238.1 - 4.9e-17 62.4 171.0 0.58 10.8 3.2 24.1 1 1 23 27 27 27 11 Clathrin-binding domain of Huntingtin-interacting protein 1 Tup_N PF08581.10 CAM45238.1 - 5.6e-17 61.8 89.1 7.9 6.9 0.4 25.9 25 1 1 26 26 26 0 Tup N-terminal Spc7 PF08317.11 CAM45238.1 - 1.2e-16 60.6 164.2 0.02 13.8 5.0 18.7 1 1 18 20 20 20 17 Spc7 kinetochore protein DUF4407 PF14362.6 CAM45238.1 - 3.3e-16 59.5 248.6 0.051 12.9 18.1 12.8 1 1 14 15 15 15 11 Domain of unknown function (DUF4407) Bap31_Bap29_C PF18035.1 CAM45238.1 - 5.6e-16 58.3 44.0 4.1 7.5 0.0 20.1 9 6 12 22 22 22 1 Bap31/Bap29 cytoplasmic coiled-coil domain USP8_interact PF08941.10 CAM45238.1 - 9.6e-15 54.8 113.2 0.25 11.1 0.5 19.5 8 6 10 20 20 20 9 USP8 interacting DUF5027 PF16430.5 CAM45238.1 - 5.6e-14 52.3 5.5 46 3.7 0.0 15.3 8 7 10 18 18 18 0 Domain of unknown function (DUF5027) NPV_P10 PF05531.12 CAM45238.1 - 7e-12 45.6 47.2 9.9 6.7 0.0 19.1 11 6 10 21 21 21 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.15 CAM45238.1 - 1.2e-11 44.2 166.4 0.86 9.4 0.7 25.8 26 0 0 26 26 26 9 Septum formation initiator DASH_Spc34 PF08657.10 CAM45238.1 - 4.3e-11 43.1 80.6 1.8 8.3 0.2 18.8 3 3 9 18 18 18 1 DASH complex subunit Spc34 Rx_N PF18052.1 CAM45238.1 - 3.3e-09 36.9 133.6 1.6 9.0 0.3 21.3 19 6 3 22 22 22 6 Rx N-terminal domain Atg14 PF10186.9 CAM45238.1 - 7e-09 35.2 136.6 0.16 11.0 4.2 17.0 1 1 11 16 16 16 10 Vacuolar sorting 38 and autophagy-related subunit 14 Myosin_tail_1 PF01576.19 CAM45238.1 - 1e-08 33.6 192.4 0.034 12.0 17.3 12.2 1 1 11 13 13 13 11 Myosin tail MscS_porin PF12795.7 CAM45238.1 - 4.9e-07 29.5 252.4 0.45 10.0 17.9 14.3 1 1 13 14 14 14 6 Mechanosensitive ion channel porin domain Syntaxin_2 PF14523.6 CAM45238.1 - 2.4e-06 27.8 34.0 81 3.7 0.0 16.6 3 1 9 19 19 19 0 Syntaxin-like protein DUF2353 PF09789.9 CAM45238.1 - 2.5e-06 27.1 127.4 1.2 8.5 2.7 19.6 1 1 17 19 19 19 2 Uncharacterized coiled-coil protein (DUF2353) Mod_r PF07200.13 CAM45238.1 - 1.7e-05 24.9 121.6 1.8 8.7 0.4 18.0 1 1 12 17 17 17 2 Modifier of rudimentary (Mod(r)) protein GAS PF13851.6 CAM45238.1 - 9.4e-05 21.9 111.1 0.73 9.2 1.0 16.4 3 3 13 19 19 19 5 Growth-arrest specific micro-tubule binding GETHR PF05671.11 CAM45238.1 - 0.00023 20.4 55.0 1.9e+02 1.5 0.0 21.2 23 0 0 23 23 23 0 GETHR pentapeptide repeat (5 copies) Ribosomal_L10 PF00466.20 CAM45238.1 - 0.00024 21.2 57.6 1.8 8.8 0.2 17.6 2 2 15 20 20 18 3 Ribosomal protein L10 MAP65_ASE1 PF03999.12 CAM45238.1 - 0.00029 19.7 27.4 0.45 9.2 0.2 8.9 2 1 1 6 6 6 2 Microtubule associated protein (MAP65/ASE1 family) MPS2 PF17060.5 CAM45238.1 - 0.00074 18.9 51.9 4.6 6.4 0.5 11.1 2 2 6 11 11 11 0 Monopolar spindle protein 2 FliJ PF02050.16 CAM45238.1 - 0.021 15.0 207.9 0.93 9.7 8.2 16.0 3 3 13 20 20 20 0 Flagellar FliJ protein CALCOCO1 PF07888.11 CAM45238.1 - 0.036 12.9 173.2 1.1 8.0 25.8 8.4 1 1 8 9 9 9 0 Calcium binding and coiled-coil domain (CALCOCO1) like AAA_13 PF13166.6 CAM45238.1 - 0.037 12.7 79.8 0.053 12.2 5.3 8.0 2 2 2 7 7 7 0 AAA domain She9_MDM33 PF05546.11 CAM45238.1 - 0.14 11.9 89.9 1.4 8.7 0.4 19.9 2 2 20 22 22 22 0 She9 / Mdm33 family DUF16 PF01519.16 CAM45238.1 - 0.24 11.9 84.5 29 5.2 0.5 20.4 2 2 15 18 18 18 0 Protein of unknown function DUF16 Med9 PF07544.13 CAM45238.1 - 0.32 11.1 144.9 7.7 6.7 0.7 24.7 26 0 0 26 26 26 0 RNA polymerase II transcription mediator complex subunit 9 TSC22 PF01166.18 CAM45238.1 - 0.53 10.6 67.1 1.3e+02 3.0 0.0 22.9 26 0 0 26 26 23 0 TSC-22/dip/bun family APG6_N PF17675.1 CAM45238.1 - 0.54 10.8 161.3 3.7 8.1 10.8 13.8 1 1 12 14 14 13 0 Apg6 coiled-coil region APG17 PF04108.12 CAM45238.1 - 0.59 9.2 80.0 3.4 6.7 0.3 11.3 2 2 3 7 7 7 0 Autophagy protein Apg17 FPP PF05911.11 CAM45238.1 - 1.2 7.3 91.5 1.2 7.2 9.6 9.0 1 1 10 11 11 10 0 Filament-like plant protein, long coiled-coil MCC-bdg_PDZ PF10506.9 CAM45238.1 - 1.8 8.7 169.4 1 9.4 1.2 24.2 23 3 2 25 25 24 0 PDZ domain of MCC-2 bdg protein for Usher syndrome AAA PF00004.29 CAM45239.1 - 0.00017 22.0 0.0 0.0018 18.7 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) COMP PF11598.8 CAM45241.1 - 4e-65 216.1 175.7 0.075 13.5 0.1 45.0 32 18 10 42 42 42 25 Cartilage oligomeric matrix protein DUF4201 PF13870.6 CAM45241.1 - 7.7e-61 204.9 62.0 7.7e-06 25.8 0.0 21.5 12 3 12 24 24 23 15 Domain of unknown function (DUF4201) TMF_DNA_bd PF12329.8 CAM45241.1 - 2.3e-59 197.3 109.6 0.012 15.5 0.2 31.1 29 3 2 31 31 31 18 TATA element modulatory factor 1 DNA binding Fez1 PF06818.15 CAM45241.1 - 4.4e-24 86.0 155.3 0.003 18.0 7.7 14.3 2 1 11 14 14 14 12 Fez1 DUF641 PF04859.12 CAM45241.1 - 1.7e-22 80.1 162.4 0.33 11.3 0.3 31.7 8 4 22 33 33 33 4 Plant protein of unknown function (DUF641) ATG16 PF08614.11 CAM45241.1 - 2.4e-22 80.2 242.7 0.00049 20.4 13.9 15.3 2 1 15 18 18 18 14 Autophagy protein 16 (ATG16) Bap31_Bap29_C PF18035.1 CAM45241.1 - 1.9e-15 56.6 49.5 6.1 6.9 0.0 23.4 8 6 16 25 25 24 2 Bap31/Bap29 cytoplasmic coiled-coil domain DUF4407 PF14362.6 CAM45241.1 - 8.8e-15 54.8 292.4 0.11 11.8 9.6 15.2 2 1 16 18 18 18 12 Domain of unknown function (DUF4407) HIP1_clath_bdg PF16515.5 CAM45241.1 - 4.8e-11 43.1 184.9 1.2 9.7 3.0 29.2 2 1 29 32 32 32 5 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF5027 PF16430.5 CAM45241.1 - 4.9e-10 39.5 9.1 66 3.2 0.0 13.8 6 4 12 18 18 18 0 Domain of unknown function (DUF5027) Ribosomal_L10 PF00466.20 CAM45241.1 - 1.1e-09 38.3 60.4 0.68 10.1 0.2 18.4 6 3 15 22 22 21 4 Ribosomal protein L10 Fib_alpha PF08702.10 CAM45241.1 - 1.9e-09 37.8 83.0 4.4 7.5 0.5 25.4 10 4 4 27 27 26 1 Fibrinogen alpha/beta chain family Spc7 PF08317.11 CAM45241.1 - 4e-09 35.8 183.8 0.25 10.2 6.5 20.6 2 1 21 23 23 23 17 Spc7 kinetochore protein Tup_N PF08581.10 CAM45241.1 - 1.9e-08 34.5 94.3 33 4.9 0.0 29.5 28 4 3 32 32 31 0 Tup N-terminal Syntaxin_2 PF14523.6 CAM45241.1 - 5.1e-08 33.2 39.0 1.1e+02 3.3 0.0 21.0 3 2 15 26 26 24 0 Syntaxin-like protein Mod_r PF07200.13 CAM45241.1 - 7.5e-07 29.4 135.8 0.63 10.1 1.4 19.7 2 1 10 17 17 17 6 Modifier of rudimentary (Mod(r)) protein USP8_interact PF08941.10 CAM45241.1 - 0.00016 21.5 117.3 0.89 9.3 0.7 21.5 7 3 14 25 25 24 5 USP8 interacting TSC22 PF01166.18 CAM45241.1 - 0.013 15.8 70.8 2e+02 2.4 0.0 26.7 31 0 0 31 31 30 0 TSC-22/dip/bun family NPV_P10 PF05531.12 CAM45241.1 - 0.019 15.4 69.9 46 4.6 0.0 22.6 17 9 6 24 24 24 0 Nucleopolyhedrovirus P10 protein PSDC PF12588.8 CAM45241.1 - 0.035 14.1 0.4 3.1 7.8 0.0 5.0 3 0 0 3 3 1 0 Phophatidylserine decarboxylase DASH_Spc34 PF08657.10 CAM45241.1 - 0.072 12.9 88.3 2.6 7.8 0.3 20.4 4 2 15 24 24 23 0 DASH complex subunit Spc34 Lzipper-MIP1 PF14389.6 CAM45241.1 - 0.093 13.0 0.1 0.093 13.0 0.1 17.6 8 6 13 22 22 21 0 Leucine-zipper of ternary complex factor MIP1 DUF2046 PF09755.9 CAM45241.1 - 0.13 11.5 66.1 1.3 8.2 0.6 12.3 2 1 12 16 16 16 0 Uncharacterized conserved protein H4 (DUF2046) MPS2 PF17060.5 CAM45241.1 - 0.17 11.1 50.1 2.4 7.3 0.1 12.2 1 1 14 16 16 16 0 Monopolar spindle protein 2 Atg14 PF10186.9 CAM45241.1 - 0.68 9.0 143.5 0.8 8.7 2.6 18.0 2 1 8 13 13 12 0 Vacuolar sorting 38 and autophagy-related subunit 14 MscS_porin PF12795.7 CAM45241.1 - 0.85 9.1 281.7 1.6 8.3 32.3 15.5 2 1 14 16 16 16 0 Mechanosensitive ion channel porin domain Phage_integrase PF00589.22 CAM45278.1 - 1.6e-06 28.1 0.1 1.2e-05 25.1 0.0 2.7 3 0 0 3 3 3 1 Phage integrase family RVT_1 PF00078.27 CAM45278.1 - 0.0022 17.5 0.0 0.0061 16.1 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A17 PF05380.13 CAM45278.1 - 0.0034 17.4 0.1 0.043 13.8 0.0 2.4 1 1 1 2 2 2 1 Pao retrotransposon peptidase TPR_20 PF14561.6 CAM45279.1 - 9.8e-05 22.6 1.1 0.011 16.1 0.0 3.7 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 CAM45279.1 - 0.00079 19.4 3.0 1 9.6 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 CAM45279.1 - 0.014 16.0 3.4 1.7 9.4 0.1 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 CAM45279.1 - 0.024 15.4 6.0 1.7 9.6 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 CAM45279.1 - 0.056 14.0 5.3 2.3 8.8 0.1 4.2 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 CAM45279.1 - 0.068 13.5 0.7 20 5.6 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 CAM45279.1 - 0.099 13.3 4.5 29 5.4 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 CAM45279.1 - 1.3 9.4 3.4 9.3 6.8 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TGT PF01702.18 CAM45281.2 - 8.3e-28 97.5 0.0 6.6e-27 94.6 0.0 1.9 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase Peptidase_M48_N PF16491.5 CAM45282.2 - 1.8e-41 142.1 3.5 3.2e-41 141.2 3.5 1.4 1 0 0 1 1 1 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 CAM45282.2 - 9.7e-39 133.2 0.0 1.6e-38 132.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 DEAD PF00270.29 CAM45283.1 - 5e-39 133.9 0.1 8.5e-39 133.1 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAM45283.1 - 7.7e-24 84.2 0.1 3.5e-20 72.4 0.0 4.0 3 1 1 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAM45283.1 - 5e-07 29.9 0.0 1.5e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF4217 PF13959.6 CAM45283.1 - 2.2e-06 27.8 0.5 5.2e-06 26.6 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) AAA_22 PF13401.6 CAM45283.1 - 2.4 8.5 6.2 1.9 8.7 1.2 3.3 3 1 0 3 3 3 0 AAA domain CcmD PF04995.14 CAM45284.1 - 0.04 14.0 0.2 0.057 13.5 0.2 1.2 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) p450 PF00067.22 CAM45287.1 - 4.2e-57 193.9 0.0 5.6e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RNA_pol_L PF01193.24 CAM45287.1 - 0.063 12.7 2.0 0.079 12.4 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Pkinase PF00069.25 CAM45288.1 - 2.4e-69 233.7 0.0 3.2e-69 233.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM45288.1 - 1.1e-28 100.2 0.0 1.7e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PUL PF08324.11 CAM45288.1 - 0.016 14.5 0.0 1.6 7.9 0.0 2.3 2 0 0 2 2 2 0 PUL domain GATA PF00320.27 CAM45288.1 - 0.028 14.0 1.0 0.066 12.8 1.0 1.5 1 0 0 1 1 1 0 GATA zinc finger PsbX PF06596.11 CAM45289.1 - 0.35 10.9 2.5 0.52 10.4 2.5 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) RINGv PF12906.7 CAM45290.1 - 2.1e-09 37.3 11.2 4.1e-09 36.4 11.2 1.5 1 0 0 1 1 1 1 RING-variant domain PHD PF00628.29 CAM45290.1 - 1.6 8.7 10.4 3 7.8 10.4 1.5 1 0 0 1 1 1 0 PHD-finger WW PF00397.26 CAM45291.1 - 5e-12 45.7 2.3 1.1e-11 44.6 2.3 1.6 1 0 0 1 1 1 1 WW domain zf_CCCH_4 PF18345.1 CAM45291.1 - 1.7e-06 27.9 3.6 3.1e-06 27.0 3.6 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 CAM45291.1 - 2.2e-06 27.4 0.7 3.5e-06 26.8 0.7 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CAM45291.1 - 2e-05 24.3 1.6 3.4e-05 23.5 1.6 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 CAM45291.1 - 0.01 16.5 0.1 0.012 16.3 0.1 1.3 1 0 0 1 1 1 0 Torus domain zf_CCCH_4 PF18345.1 CAM45293.1 - 8.9e-07 28.8 2.6 1.3e-06 28.2 2.6 1.3 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 CAM45293.1 - 9.3e-07 29.5 0.1 1.6e-06 28.8 0.1 1.3 1 0 0 1 1 1 1 Torus domain zf-CCCH_4 PF18044.1 CAM45293.1 - 2.8e-06 27.0 1.2 4e-06 26.5 1.2 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 CAM45293.1 - 0.002 18.0 0.3 0.0029 17.5 0.3 1.2 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 CAM45293.1 - 0.0036 17.7 2.3 0.006 17.0 2.3 1.3 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger SET PF00856.28 CAM45294.1 - 2.8e-13 50.6 0.0 1.3e-12 48.4 0.0 1.9 1 1 0 1 1 1 1 SET domain OSTMP1 PF09777.9 CAM45294.1 - 0.0075 15.7 0.2 0.012 15.1 0.2 1.3 1 0 0 1 1 1 1 Osteopetrosis-associated transmembrane protein 1 precursor Proteasome PF00227.26 CAM45297.1 - 1.7e-42 145.1 0.1 2.2e-42 144.7 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CAM45297.1 - 1.2e-08 34.5 0.1 1.2e-08 34.5 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Torus PF16131.5 CAM45298.1 - 0.0015 19.2 0.1 0.0029 18.3 0.1 1.4 1 0 0 1 1 1 1 Torus domain Inhibitor_I36 PF03995.13 CAM45298.1 - 0.017 15.0 0.1 1.9 8.4 0.0 3.0 3 0 0 3 3 3 0 Peptidase inhibitor family I36 PetM PF08041.11 CAM45298.1 - 0.51 10.0 2.6 0.86 9.2 2.6 1.4 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 VIT1 PF01988.19 CAM45299.1 - 1.3e-50 172.3 4.9 1.6e-50 172.0 4.9 1.1 1 0 0 1 1 1 1 VIT family Exotox-A_target PF09102.10 CAM45299.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Exotoxin A, targeting THF_DHG_CYH_C PF02882.19 CAM45300.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF3295 PF11702.8 CAM45301.1 - 0.3 10.4 1.7 5.3 6.3 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3295) Casc1_N PF15927.5 CAM45303.1 - 0.069 12.8 241.8 3.1 7.4 16.9 10.2 1 1 10 11 11 11 0 Cancer susceptibility candidate 1 N-terminus XPG_I PF00867.18 CAM45304.1 - 4.6e-31 107.0 0.1 8.5e-31 106.2 0.1 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 CAM45304.1 - 5.7e-27 94.2 0.0 1.1e-26 93.3 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 CAM45304.1 - 7.2e-06 26.5 0.0 6.5e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold XRN_N PF03159.18 CAM45304.1 - 0.035 13.5 0.0 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus Peptidase_M20 PF01546.28 CAM45304.1 - 0.16 11.6 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Ifi-6-16 PF06140.13 CAM45305.2 - 0.13 12.1 0.0 0.53 10.2 0.0 1.9 2 0 0 2 2 2 0 Interferon-induced 6-16 family EcsC PF12787.7 CAM45306.1 - 4.4 6.9 6.7 0.54 9.9 0.5 2.2 2 0 0 2 2 2 0 EcsC protein family CoA_binding PF02629.19 CAM45306.1 - 5.5 7.7 5.1 5.4 7.8 0.1 2.8 3 0 0 3 3 3 0 CoA binding domain PP-binding PF00550.25 CAM45307.1 - 1.1e-10 41.7 0.1 1.4e-10 41.3 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site MM_CoA_mutase PF01642.22 CAM45308.1 - 4.1e-227 754.8 1.7 4.9e-227 754.5 1.7 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 CAM45308.1 - 2.4e-13 50.2 0.1 6e-13 48.9 0.1 1.7 1 0 0 1 1 1 1 B12 binding domain HisG_C PF08029.11 CAM45308.1 - 0.075 13.2 0.0 0.21 11.8 0.0 1.8 1 0 0 1 1 1 0 HisG, C-terminal domain TIP120 PF08623.10 CAM45309.2 - 9.6e-09 35.2 0.3 8e-08 32.2 0.0 2.4 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) Adaptin_N PF01602.20 CAM45309.2 - 0.0016 17.1 6.9 0.0085 14.7 0.5 3.5 3 0 0 3 3 3 2 Adaptin N terminal region Spidroin_MaSp PF11260.8 CAM45309.2 - 8.7 6.7 13.8 0.5 10.7 0.1 4.3 4 0 0 4 4 4 0 Major ampullate spidroin 1 and 2 Urb2 PF10441.9 CAM45310.2 - 0.13 12.2 0.5 0.32 10.9 0.5 1.8 1 1 0 1 1 1 0 Urb2/Npa2 family TSNAXIP1_N PF15739.5 CAM45311.1 - 6.5e-18 65.1 4.9 6.5e-18 65.1 4.9 2.7 2 0 0 2 2 2 1 Translin-associated factor X-interacting N-terminus Arg_decarbox_C PF17944.1 CAM45311.1 - 1.4 9.6 4.1 28 5.3 0.3 3.8 4 0 0 4 4 4 0 Arginine decarboxylase C-terminal helical extension E2R135 PF11570.8 CAM45311.1 - 1.6 9.0 6.9 11 6.3 2.8 2.4 1 1 1 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 Pkinase PF00069.25 CAM45313.1 - 9.6e-64 215.3 0.0 3.6e-63 213.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM45313.1 - 1.4e-22 80.3 0.0 8.5e-22 77.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM45313.1 - 5.2e-06 26.0 0.2 0.046 13.0 0.2 3.0 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.14 CAM45313.1 - 0.0014 18.0 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 CAM45313.1 - 0.03 13.9 0.3 2.5 7.6 0.2 2.5 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 CAM45313.1 - 0.033 13.0 0.0 0.05 12.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 CAM45313.1 - 0.043 13.4 0.1 0.23 11.1 0.1 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 zf-U1 PF06220.12 CAM45315.1 - 0.38 10.6 2.7 0.28 11.0 0.2 2.2 2 0 0 2 2 2 0 U1 zinc finger Kri1 PF05178.12 CAM45316.1 - 1.3e-19 70.7 9.5 1.3e-19 70.7 9.5 5.0 5 0 0 5 5 5 1 KRI1-like family Kri1_C PF12936.7 CAM45316.1 - 2.3e-18 66.1 0.1 1.2e-17 63.9 0.1 2.3 1 0 0 1 1 1 1 KRI1-like family C-terminal STT3 PF02516.14 CAM45320.1 - 1.4e-46 159.5 30.1 5.4e-43 147.6 27.1 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit RRM_1 PF00076.22 CAM45321.1 - 2.9e-17 62.2 0.0 1.3e-08 34.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA PF00004.29 CAM45322.1 - 8.8e-36 123.2 0.0 9.8e-35 119.9 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CAM45322.1 - 2e-08 34.8 0.2 0.032 14.6 0.0 3.4 2 1 0 3 3 3 2 AAA ATPase domain AAA_lid_3 PF17862.1 CAM45322.1 - 4.7e-08 32.7 0.1 1.3e-07 31.3 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain Rad17 PF03215.15 CAM45322.1 - 0.00013 22.0 0.0 0.0084 16.0 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_5 PF07728.14 CAM45322.1 - 0.0023 17.9 0.0 0.01 15.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CAM45322.1 - 0.01 16.1 0.1 7.8 6.8 0.1 3.7 2 2 2 4 4 4 0 AAA domain RNA_helicase PF00910.22 CAM45322.1 - 0.015 15.6 0.0 0.28 11.6 0.0 2.3 2 0 0 2 2 2 0 RNA helicase DUF815 PF05673.13 CAM45322.1 - 0.022 14.0 0.0 1.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 CAM45322.1 - 0.04 13.4 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 CAM45322.1 - 0.041 14.1 0.0 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 CAM45322.1 - 0.067 13.2 0.0 0.63 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 CAM45322.1 - 0.089 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 CAM45322.1 - 0.13 12.2 0.0 1.3 8.9 0.0 2.3 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Herpes_UL49_5 PF05702.11 CAM45323.1 - 0.1 12.7 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein Nup96 PF12110.8 CAM45324.2 - 2.5e-34 118.7 0.0 4.2e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 CAM45324.2 - 6.6e-14 52.3 0.0 1.5e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 Nucleoporin autopeptidase KIP1 PF07765.12 CAM45326.1 - 0.0015 18.6 2.2 0.066 13.3 0.4 2.2 1 1 1 2 2 2 2 KIP1-like protein DUF1664 PF07889.12 CAM45326.1 - 0.019 15.0 1.9 0.034 14.2 1.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) G-gamma PF00631.22 CAM45326.1 - 0.1 12.6 0.1 0.19 11.7 0.1 1.5 1 1 0 1 1 1 0 GGL domain DnaJ PF00226.31 CAM45327.2 - 7.2e-25 86.9 0.7 1.3e-24 86.1 0.7 1.4 1 0 0 1 1 1 1 DnaJ domain TrbE PF11100.8 CAM45327.2 - 0.11 12.8 0.4 0.22 11.8 0.4 1.4 1 0 0 1 1 1 0 Conjugal transfer protein TrbE PfkB PF00294.24 CAM45328.1 - 2.2e-67 227.5 0.0 2.5e-67 227.3 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 CAM45328.1 - 5e-08 32.6 0.0 7.3e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Mur_ligase PF01225.25 CAM45328.1 - 0.015 15.6 0.1 0.12 12.7 0.0 2.6 2 1 1 3 3 3 0 Mur ligase family, catalytic domain Gly_reductase PF09338.11 CAM45328.1 - 0.14 10.5 2.5 0.34 9.3 0.2 2.0 2 0 0 2 2 2 0 Glycine/sarcosine/betaine reductase component B subunits Brix PF04427.18 CAM45331.1 - 2e-27 96.5 0.1 4e-27 95.6 0.1 1.5 1 0 0 1 1 1 1 Brix domain Vasohibin PF14822.6 CAM45332.2 - 4.8e-47 160.3 0.0 7.9e-47 159.5 0.0 1.3 1 0 0 1 1 1 1 Vasohibin KIP1 PF07765.12 CAM45333.1 - 0.0015 18.6 2.2 0.066 13.3 0.4 2.2 1 1 1 2 2 2 2 KIP1-like protein DUF1664 PF07889.12 CAM45333.1 - 0.019 15.0 1.9 0.034 14.2 1.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) G-gamma PF00631.22 CAM45333.1 - 0.1 12.6 0.1 0.19 11.7 0.1 1.5 1 1 0 1 1 1 0 GGL domain DnaJ PF00226.31 CAM45334.1 - 2.3e-25 88.5 0.7 3.1e-25 88.1 0.7 1.2 1 0 0 1 1 1 1 DnaJ domain ABC_membrane_2 PF06472.15 CAM45335.1 - 9.6e-24 84.2 0.5 9.6e-24 84.2 0.5 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 CAM45335.1 - 1.2e-14 55.0 0.0 2.5e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CAM45335.1 - 3.4e-07 29.9 0.0 1.3e-05 24.7 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 CAM45335.1 - 8.7e-05 22.5 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain ABC_membrane PF00664.23 CAM45335.1 - 0.00016 21.5 1.1 0.00016 21.5 1.1 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region Helo_like_N PF17111.5 CAM45335.1 - 0.0054 16.1 1.8 1.4 8.2 0.2 2.4 2 0 0 2 2 2 2 Fungal N-terminal domain of STAND proteins AAA_22 PF13401.6 CAM45335.1 - 0.0056 16.9 0.5 0.082 13.2 0.5 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CAM45335.1 - 0.014 15.8 0.0 0.031 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 CAM45335.1 - 0.016 15.7 0.0 0.028 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain HTH_43 PF09904.9 CAM45335.1 - 0.065 13.2 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn helix AAA_21 PF13304.6 CAM45335.1 - 0.095 12.5 0.0 0.25 11.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF3584 PF12128.8 CAM45335.1 - 0.11 10.0 0.0 0.17 9.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_15 PF13175.6 CAM45335.1 - 0.19 11.4 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain SH3_3 PF08239.11 CAM45336.2 - 0.045 14.0 0.0 9.1 6.6 0.0 2.8 2 0 0 2 2 2 0 Bacterial SH3 domain Peptidase_C2 PF00648.21 CAM45337.2 - 1.7e-85 286.7 0.0 1.3e-32 113.0 0.0 3.3 3 0 0 3 3 3 3 Calpain family cysteine protease Calpain_III PF01067.22 CAM45337.2 - 9.8e-21 74.5 0.0 1.1e-07 32.2 0.0 4.0 3 0 0 3 3 3 3 Calpain large subunit, domain III Rrp15p PF07890.12 CAM45337.2 - 0.94 9.8 3.7 1.3 9.4 0.2 3.3 2 0 0 2 2 2 0 Rrp15p Peptidase_C2 PF00648.21 CAM45338.2 - 1.2e-98 329.8 0.0 1.8e-37 129.0 0.0 3.2 3 0 0 3 3 3 3 Calpain family cysteine protease Calpain_III PF01067.22 CAM45338.2 - 1.5e-19 70.7 0.0 1e-06 29.0 0.0 4.0 3 0 0 3 3 3 3 Calpain large subunit, domain III DUF3470 PF11953.8 CAM45338.2 - 7.9 6.5 12.0 7.5 6.6 0.0 5.6 5 0 0 5 5 5 0 Domain of unknown function (DUF3470) Peptidase_C2 PF00648.21 CAM45339.1 - 5.8e-36 124.0 0.0 8.3e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 CAM45339.1 - 9.6e-05 22.7 0.0 0.0002 21.6 0.0 1.5 1 0 0 1 1 1 1 Calpain large subunit, domain III Radial_spoke_3 PF06098.11 CAM45340.1 - 7.4e-108 360.2 28.0 8.9e-108 359.9 28.0 1.1 1 0 0 1 1 1 1 Radial spoke protein 3 Amastin PF07344.11 CAM45342.1 - 2.3e-08 34.0 6.1 2.3e-08 34.0 6.1 1.6 2 0 0 2 2 2 1 Amastin surface glycoprotein CRPA PF05745.11 CAM45342.1 - 6.3 6.8 6.3 1.1 9.3 2.1 1.7 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Rep_fac_C PF08542.11 CAM45343.1 - 6.8e-19 68.1 0.1 4.5e-18 65.5 0.0 2.2 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 CAM45343.1 - 2.2e-12 47.1 0.0 1.7e-11 44.2 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 CAM45343.1 - 1.8e-11 44.6 0.2 8.3e-11 42.4 0.0 2.2 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CAM45343.1 - 1.8e-07 31.3 0.0 3.4e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 CAM45343.1 - 4.3e-07 30.3 0.0 1.4e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CAM45343.1 - 2.6e-05 23.7 0.1 0.00043 19.7 0.1 2.2 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 CAM45343.1 - 3.3e-05 24.4 1.0 0.00049 20.5 1.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 CAM45343.1 - 0.0001 22.6 1.0 0.0092 16.3 0.1 2.6 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 CAM45343.1 - 0.00012 21.9 0.1 0.0004 20.2 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 CAM45343.1 - 0.00014 22.1 0.0 0.00035 20.9 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain DNA_pol3_delta PF06144.13 CAM45343.1 - 0.00067 19.5 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_24 PF13479.6 CAM45343.1 - 0.0015 18.3 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CAM45343.1 - 0.0047 16.7 0.1 0.014 15.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CAM45343.1 - 0.0059 16.4 0.0 0.0084 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 CAM45343.1 - 0.0071 15.9 0.4 0.019 14.5 0.1 1.9 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CAM45343.1 - 0.011 16.1 0.0 0.042 14.2 0.0 2.0 2 0 0 2 2 1 0 RNA helicase AAA_5 PF07728.14 CAM45343.1 - 0.014 15.4 0.0 0.3 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MCM PF00493.23 CAM45343.1 - 0.033 13.3 0.1 2.8 7.0 0.0 2.5 2 1 0 2 2 2 0 MCM P-loop domain DUF2075 PF09848.9 CAM45343.1 - 0.042 13.1 0.0 0.067 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 CAM45343.1 - 0.046 13.8 0.0 0.21 11.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain PrpR_N PF06506.11 CAM45343.1 - 0.068 12.8 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Propionate catabolism activator AAA_18 PF13238.6 CAM45343.1 - 0.07 13.7 0.0 0.16 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CAM45343.1 - 0.078 13.1 0.0 0.23 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 CAM45344.1 - 1.1e-61 208.5 0.0 1.3e-61 208.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM45344.1 - 1.1e-26 93.7 0.0 1.5e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAM45344.1 - 0.0053 15.6 0.0 0.03 13.1 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CAM45344.1 - 0.014 15.4 0.0 0.028 14.4 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 CAM45344.1 - 0.02 14.5 0.0 3.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Lambda_Kil PF06301.11 CAM45344.1 - 0.2 11.3 0.0 0.35 10.5 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage lambda Kil protein zf-RING_2 PF13639.6 CAM45345.2 - 6.2e-09 36.1 9.4 6.2e-09 36.1 9.4 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 CAM45345.2 - 2.7e-07 30.3 8.2 2.7e-07 30.3 8.2 2.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CAM45345.2 - 6.3e-06 26.0 8.0 6.3e-06 26.0 8.0 2.9 3 1 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CAM45345.2 - 9.5e-06 25.4 6.3 9.5e-06 25.4 6.3 2.9 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CAM45345.2 - 2.7e-05 24.1 6.7 2.7e-05 24.1 6.7 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CAM45345.2 - 6.9e-05 22.6 7.8 6.9e-05 22.6 7.8 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CAM45345.2 - 8.7e-05 22.3 8.7 8.7e-05 22.3 8.7 2.9 3 1 0 3 3 2 1 Prokaryotic RING finger family 4 zf-UDP PF14569.6 CAM45345.2 - 0.00031 20.8 2.6 0.00031 20.8 2.6 2.1 2 0 0 2 2 1 1 Zinc-binding RING-finger zf-rbx1 PF12678.7 CAM45345.2 - 0.00079 19.7 10.7 0.00079 19.7 10.7 2.8 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CAM45345.2 - 0.005 16.9 2.0 0.005 16.9 2.0 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 CAM45345.2 - 0.031 14.4 5.6 0.031 14.4 5.6 2.7 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-ACC PF17848.1 CAM45345.2 - 0.074 13.1 0.6 0.32 11.1 0.6 2.1 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain zf-RING_11 PF17123.5 CAM45345.2 - 0.26 11.1 6.2 0.97 9.2 6.2 2.0 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_6 PF14835.6 CAM45345.2 - 0.39 10.6 3.4 1.6 8.7 3.4 2.1 1 0 0 1 1 1 0 zf-RING of BARD1-type protein FYVE_2 PF02318.16 CAM45345.2 - 0.92 9.7 12.1 3.1 8.0 1.6 2.6 2 0 0 2 2 2 0 FYVE-type zinc finger FANCL_C PF11793.8 CAM45345.2 - 3.3 8.0 18.3 2.6 8.3 3.3 3.2 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_4 PF14570.6 CAM45345.2 - 3.4 7.6 21.7 0.068 13.0 8.1 3.1 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.7 CAM45345.2 - 4 7.5 21.2 0.034 14.2 5.3 3.3 3 1 1 4 4 4 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 CAM45345.2 - 5.6 6.8 7.1 35 4.3 4.5 3.1 2 1 0 2 2 2 0 zinc-ribbon domain ANAPC4_WD40 PF12894.7 CAM45346.1 - 2.7e-07 30.8 0.1 0.43 10.9 0.0 4.2 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CAM45346.1 - 1.2e-05 26.0 1.8 11 7.1 0.0 5.1 4 0 0 4 4 4 2 WD domain, G-beta repeat LisH PF08513.11 CAM45346.1 - 6.2e-05 22.8 0.2 0.00011 22.0 0.2 1.4 1 0 0 1 1 1 1 LisH LisH_TPL PF17814.1 CAM45346.1 - 0.0086 15.7 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 LisH-like dimerisation domain DUF4471 PF14740.6 CAM45347.1 - 3e-67 227.0 0.0 5.3e-67 226.2 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4471) DUF4470 PF14737.6 CAM45347.1 - 1.7e-15 57.0 0.0 1.2e-14 54.2 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4470) DUF148 PF02520.17 CAM45347.1 - 0.35 11.0 1.5 2.9 8.0 0.4 2.2 1 1 0 2 2 2 0 Domain of unknown function DUF148 MRPL52 PF18699.1 CAM45348.2 - 2.3 8.5 4.9 3.7 7.8 0.0 3.1 3 0 0 3 3 3 0 Mitoribosomal protein mL52 MRP-S28 PF10213.9 CAM45351.1 - 0.00095 19.6 0.0 0.003 18.0 0.0 1.8 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Aa_trans PF01490.18 CAM45354.2 - 2.8e-41 141.6 35.4 3.5e-41 141.3 35.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CAM45354.2 - 3.5e-09 36.2 20.7 8.7e-09 34.9 20.7 1.6 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family AA_permease_2 PF13520.6 CAM45354.2 - 2.6e-07 29.8 25.1 2.6e-07 29.8 25.1 2.0 2 0 0 2 2 2 1 Amino acid permease VIT1 PF01988.19 CAM45354.2 - 0.039 13.8 0.0 0.039 13.8 0.0 3.3 3 0 0 3 3 3 0 VIT family FAD_binding_4 PF01565.23 CAM45355.1 - 0.0043 16.8 0.6 0.014 15.1 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain DUF1860 PF08949.10 CAM45355.1 - 0.031 14.0 0.0 0.7 9.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1860) LRR_4 PF12799.7 CAM45355.1 - 0.041 14.3 0.5 0.83 10.2 0.0 3.1 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) UBA PF00627.31 CAM45357.2 - 1.7e-08 34.2 0.1 3.8e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.6 CAM45357.2 - 0.14 12.0 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain NAD_binding_1 PF00175.21 CAM45358.1 - 6.9e-19 68.5 0.0 9.6e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CAM45358.1 - 2.3e-05 24.6 0.0 0.0003 20.9 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Oxidored_q6 PF01058.22 CAM45359.1 - 2.8e-19 69.3 0.0 3.6e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Dabb PF07876.12 CAM45360.1 - 1.7e-08 34.9 0.0 2.4e-08 34.5 0.0 1.3 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain DsbC_N PF10411.9 CAM45360.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Disulfide bond isomerase protein N-terminus Dabb PF07876.12 CAM45361.1 - 0.00026 21.5 0.0 0.00034 21.2 0.0 1.3 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain Ras PF00071.22 CAM45362.1 - 3.4e-64 215.3 0.6 3.9e-64 215.1 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAM45362.1 - 8e-37 126.1 0.1 1.4e-36 125.4 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAM45362.1 - 7.3e-16 58.1 0.1 8.8e-16 57.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CAM45362.1 - 5.7e-07 29.6 0.5 0.0098 15.8 0.2 2.3 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 CAM45362.1 - 2.1e-06 27.3 0.1 2.5e-06 27.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CAM45362.1 - 3.5e-05 23.3 0.2 4.6e-05 22.9 0.2 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CAM45362.1 - 9.2e-05 22.1 0.3 0.00021 20.9 0.3 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CAM45362.1 - 0.00018 21.6 0.1 0.00045 20.3 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CAM45362.1 - 0.0007 19.1 0.1 0.0038 16.8 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA PF00004.29 CAM45362.1 - 0.0059 17.0 0.0 0.41 11.1 0.0 2.3 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CAM45362.1 - 0.018 15.4 0.0 0.03 14.7 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 CAM45362.1 - 0.025 15.1 0.2 0.15 12.6 0.2 1.9 1 1 0 1 1 1 0 ABC transporter G-alpha PF00503.20 CAM45362.1 - 0.033 13.4 3.9 0.14 11.3 0.7 2.5 1 1 1 2 2 2 0 G-protein alpha subunit AAA_22 PF13401.6 CAM45362.1 - 0.047 14.0 0.0 0.13 12.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CAM45362.1 - 0.066 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 CAM45362.1 - 0.11 12.0 0.0 0.25 10.7 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein DUF4093 PF13331.6 CAM45363.2 - 0.21 12.0 0.1 0.92 10.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4093) Tnp_zf-ribbon_2 PF13842.6 CAM45363.2 - 8.3 7.3 6.6 1.2 10.0 0.3 2.4 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon MCU PF04678.13 CAM45364.1 - 3.9e-41 141.1 0.0 5.6e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial calcium uniporter Glyoxalase_4 PF13669.6 CAM45364.1 - 0.074 13.3 0.0 0.16 12.3 0.0 1.6 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily LRR_6 PF13516.6 CAM45365.2 - 1.6e-05 24.6 6.3 0.016 15.2 0.6 4.3 5 0 0 5 5 5 2 Leucine Rich repeat LRR_8 PF13855.6 CAM45365.2 - 0.11 12.3 2.0 1.4 8.8 1.4 3.0 2 1 0 2 2 2 0 Leucine rich repeat Beta_helix PF13229.6 CAM45366.2 - 3.7e-100 332.3 96.9 3.8e-15 56.1 8.7 16.1 10 5 4 15 15 15 13 Right handed beta helix region NosD PF05048.13 CAM45366.2 - 1.8e-79 266.4 40.2 6.3e-14 51.8 5.2 15.2 10 4 6 16 16 16 14 Periplasmic copper-binding protein (NosD) End3 PF12761.7 CAM45366.2 - 0.04 14.1 0.1 0.075 13.2 0.1 1.4 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF1565 PF07602.11 CAM45366.2 - 0.1 11.9 55.6 0.24 10.7 0.0 12.3 8 5 3 13 13 13 0 Protein of unknown function (DUF1565) FliJ PF02050.16 CAM45366.2 - 0.18 12.0 1.0 0.4 10.9 1.0 1.5 1 0 0 1 1 1 0 Flagellar FliJ protein SDH_alpha PF03313.15 CAM45367.1 - 0.19 11.4 0.0 0.45 10.1 0.0 1.6 2 0 0 2 2 2 0 Serine dehydratase alpha chain SKI PF01202.22 CAM45367.1 - 0.2 11.8 1.7 2.4 8.3 1.0 2.4 2 0 0 2 2 2 0 Shikimate kinase FUSC PF04632.12 CAM45367.1 - 2 6.8 7.1 26 3.2 5.4 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family HrpB1_HrpK PF09613.10 CAM45368.2 - 0.014 15.1 0.9 0.049 13.3 0.4 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) PreAtp-grasp PF18604.1 CAM45368.2 - 0.097 12.3 0.2 0.47 10.1 0.3 2.1 2 0 0 2 2 2 0 Pre ATP-grasp domain WD40 PF00400.32 CAM45370.1 - 2.7e-05 24.8 14.4 0.13 13.2 0.0 6.4 5 0 0 5 5 5 2 WD domain, G-beta repeat PQQ_3 PF13570.6 CAM45370.1 - 4.3 8.0 8.9 4.5 7.9 0.0 5.5 6 0 0 6 6 6 0 PQQ-like domain DUF1126 PF06565.12 CAM45371.1 - 6.5e-78 257.3 3.4 1.7e-25 88.9 0.1 3.4 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_7 PF13499.6 CAM45371.1 - 8.4e-07 29.4 2.2 1.2e-05 25.6 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.6 CAM45371.1 - 0.00028 20.7 0.4 0.17 11.7 0.0 3.2 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CAM45371.1 - 0.0068 16.3 0.2 5.2 7.3 0.1 3.9 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 CAM45371.1 - 0.016 14.7 0.2 18 5.1 0.0 4.6 4 0 0 4 4 4 0 EF hand Sep15_SelM PF08806.11 CAM45372.1 - 0.011 15.8 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 0 Sep15/SelM redox domain E1_dh PF00676.20 CAM45373.1 - 1.1e-55 188.8 0.0 1.8e-55 188.0 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 CAM45373.1 - 5.5e-48 163.0 0.0 9.3e-48 162.2 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 CAM45373.1 - 1.8e-35 121.9 0.1 3.5e-35 120.9 0.1 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 CAM45373.1 - 0.00032 20.2 0.2 0.00074 19.1 0.2 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus PIP5K PF01504.18 CAM45374.2 - 9.9e-34 116.8 0.0 2.6e-15 56.4 0.0 3.2 2 1 1 3 3 3 3 Phosphatidylinositol-4-phosphate 5-Kinase FYVE PF01363.21 CAM45374.2 - 8e-15 54.7 5.5 1.7e-14 53.7 5.5 1.6 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.21 CAM45374.2 - 0.23 11.7 3.5 0.59 10.4 3.5 1.6 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain ATG16 PF08614.11 CAM45374.2 - 0.65 10.2 3.4 2.1 8.5 3.4 1.8 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF778 PF05608.12 CAM45375.1 - 1.1e-34 120.5 2.8 4.7e-20 72.8 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF778) DUF4796 PF16044.5 CAM45375.1 - 0.0038 16.9 0.5 0.01 15.4 0.5 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4796) LRAT PF04970.13 CAM45375.1 - 0.072 13.4 0.1 0.1 12.9 0.1 1.2 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Peptidase_C97 PF05903.14 CAM45375.1 - 0.18 11.6 0.3 0.28 11.0 0.3 1.3 1 0 0 1 1 1 0 PPPDE putative peptidase domain Pep3_Vps18 PF05131.14 CAM45376.1 - 8.2e-10 38.7 0.0 2.9e-08 33.6 0.0 3.0 2 1 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 CAM45376.1 - 6.4e-08 32.6 0.1 2.3e-07 30.8 0.1 1.9 1 1 0 1 1 1 1 Region in Clathrin and VPS Vps39_2 PF10367.9 CAM45376.1 - 3.7e-05 24.1 0.2 7.9e-05 23.1 0.2 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Zn_ribbon_17 PF17120.5 CAM45376.1 - 0.00048 19.7 1.6 0.0023 17.5 1.6 2.1 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Clathrin_H_link PF13838.6 CAM45376.1 - 0.0086 16.0 0.0 0.046 13.6 0.0 2.2 2 0 0 2 2 2 1 Clathrin-H-link zf-RING_5 PF14634.6 CAM45376.1 - 0.021 14.8 2.6 0.066 13.2 2.6 1.9 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 CAM45376.1 - 0.075 13.1 2.5 0.21 11.7 2.5 1.8 1 0 0 1 1 1 0 RING-type zinc-finger VPS11_C PF12451.8 CAM45376.1 - 0.22 11.8 0.4 0.49 10.7 0.4 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal CTU2 PF10288.9 CAM45376.1 - 0.43 10.9 1.7 0.47 10.7 0.2 1.8 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF1295 PF06966.12 CAM45377.1 - 2.8e-29 102.3 10.1 8e-29 100.8 10.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) DUF4010 PF13194.6 CAM45377.1 - 0.016 14.9 0.8 0.016 14.9 0.8 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4010) H_PPase PF03030.16 CAM45377.1 - 1.5 7.4 3.5 8.4 4.9 0.4 2.0 2 0 0 2 2 2 0 Inorganic H+ pyrophosphatase Acyl-CoA_dh_1 PF00441.24 CAM45378.1 - 1.4e-40 138.9 0.4 2.9e-40 137.9 0.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CAM45378.1 - 3.4e-28 98.6 0.0 1e-27 97.0 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CAM45378.1 - 5e-24 84.3 0.1 9.7e-24 83.4 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CAM45378.1 - 1.2e-19 70.9 0.1 2.7e-19 69.8 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 CAM45378.1 - 0.077 13.6 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal XRN_N PF03159.18 CAM45379.2 - 6.4e-28 97.8 0.0 1e-27 97.2 0.0 1.2 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus ABC2_membrane_3 PF12698.7 CAM45382.2 - 8e-64 215.9 56.4 2.4e-40 138.7 23.8 3.0 2 2 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 CAM45382.2 - 1.5e-52 177.8 0.0 4.7e-27 95.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CAM45382.2 - 6.2e-17 62.4 0.1 7.8e-06 25.9 0.0 4.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 CAM45382.2 - 5.8e-05 23.7 0.0 0.12 13.1 0.1 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4162) Zeta_toxin PF06414.12 CAM45382.2 - 7.3e-05 22.1 0.7 0.1 11.8 0.3 3.2 3 0 0 3 3 3 1 Zeta toxin SMC_N PF02463.19 CAM45382.2 - 0.00033 20.2 0.0 4.9 6.5 0.0 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CAM45382.2 - 0.00045 20.2 0.0 0.023 14.6 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 CAM45382.2 - 0.00068 19.3 0.4 0.18 11.6 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 CAM45382.2 - 0.0013 18.5 0.0 0.074 12.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 CAM45382.2 - 0.0018 18.5 0.0 2.5 8.4 0.0 4.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SRP54 PF00448.22 CAM45382.2 - 0.0045 16.7 0.2 1.2 8.8 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_15 PF13175.6 CAM45382.2 - 0.011 15.5 1.4 2.9 7.5 0.0 3.6 4 0 0 4 4 4 0 AAA ATPase domain AAA_23 PF13476.6 CAM45382.2 - 0.021 15.3 9.5 0.29 11.6 0.1 2.9 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 CAM45382.2 - 0.084 13.3 0.2 22 5.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase MMR_HSR1 PF01926.23 CAM45382.2 - 0.089 12.9 0.1 6.8 6.8 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.6 CAM45382.2 - 0.1 13.0 0.0 2.4 8.5 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain MukB PF04310.12 CAM45382.2 - 0.17 11.7 0.9 4.5 7.0 0.1 2.4 2 0 0 2 2 2 0 MukB N-terminal AAA_27 PF13514.6 CAM45382.2 - 0.21 11.2 0.4 4.4 6.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 CAM45382.2 - 0.99 9.4 2.8 7.7 6.5 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain ABC2_membrane PF01061.24 CAM45382.2 - 1.5 8.2 54.6 0.012 15.1 16.7 3.7 5 0 0 5 5 5 0 ABC-2 type transporter DUF4162 PF13732.6 CAM45383.2 - 0.00095 19.8 0.1 0.0015 19.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) TatD_DNase PF01026.21 CAM45385.1 - 1.2e-37 129.6 0.0 1.5e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 CAM45385.1 - 5.6e-06 26.3 0.0 0.038 13.8 0.0 2.6 2 1 0 2 2 2 2 Amidohydrolase Sec6 PF06046.13 CAM45386.1 - 1e-10 40.7 0.2 1.4e-07 30.3 1.9 2.5 2 0 0 2 2 2 2 Exocyst complex component Sec6 DUF896 PF05979.12 CAM45387.1 - 0.039 13.8 0.4 0.43 10.5 0.1 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) DUF2894 PF11445.8 CAM45387.1 - 0.068 13.6 1.0 0.068 13.6 1.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) Pyridox_ox_2 PF12900.7 CAM45387.1 - 0.12 12.4 0.0 0.29 11.1 0.0 1.8 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Caskin-Pro-rich PF16907.5 CAM45388.2 - 0.018 15.6 1.7 0.046 14.2 1.7 1.7 1 0 0 1 1 1 0 Proline rich region of Caskin proteins FAM117 PF15388.6 CAM45388.2 - 0.54 9.6 6.4 1.1 8.6 6.4 1.5 1 0 0 1 1 1 0 Protein Family FAM117 AAA PF00004.29 CAM45391.1 - 5.3e-87 289.0 0.0 1.3e-47 161.5 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAM45391.1 - 7.4e-24 83.3 1.6 6.5e-12 45.1 0.0 3.1 3 0 0 3 3 2 2 AAA+ lid domain RuvB_N PF05496.12 CAM45391.1 - 1.1e-15 57.8 0.0 8.5e-08 32.1 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CAM45391.1 - 8e-13 49.1 2.1 0.00031 21.2 0.1 4.3 3 2 2 5 5 4 2 AAA ATPase domain AAA_5 PF07728.14 CAM45391.1 - 2.4e-11 43.8 0.0 0.00012 22.1 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CAM45391.1 - 9.7e-11 42.1 0.0 2.4e-05 24.5 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CAM45391.1 - 4.2e-09 36.8 0.3 0.013 15.8 0.0 4.2 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.6 CAM45391.1 - 5.8e-09 36.3 0.0 0.0016 18.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 CAM45391.1 - 5.5e-07 29.7 0.0 0.026 14.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CAM45391.1 - 1e-06 29.1 0.0 0.034 14.5 0.0 2.9 3 0 0 3 3 2 2 RNA helicase IstB_IS21 PF01695.17 CAM45391.1 - 4.6e-06 26.5 0.0 0.13 12.0 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 CAM45391.1 - 7.8e-06 26.5 0.0 0.065 13.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 CAM45391.1 - 1.7e-05 24.8 0.0 0.28 11.2 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 CAM45391.1 - 1.8e-05 24.2 0.0 0.16 11.2 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain Zeta_toxin PF06414.12 CAM45391.1 - 2.2e-05 23.8 0.0 0.021 14.1 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin Mg_chelatase PF01078.21 CAM45391.1 - 4.7e-05 22.9 0.1 0.049 13.0 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CAM45391.1 - 7.3e-05 22.6 0.0 0.51 10.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 CAM45391.1 - 8.2e-05 22.6 0.1 0.38 10.7 0.0 3.0 3 0 0 3 3 3 2 NACHT domain AAA_24 PF13479.6 CAM45391.1 - 0.00012 21.9 0.0 0.49 10.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 CAM45391.1 - 0.00016 21.9 0.0 0.37 11.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 CAM45391.1 - 0.0002 21.9 0.0 0.39 11.2 0.0 2.8 2 1 0 2 2 2 1 ABC transporter AAA_11 PF13086.6 CAM45391.1 - 0.00043 20.2 0.0 0.72 9.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 CAM45391.1 - 0.00045 20.0 0.0 0.093 12.4 0.0 2.8 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_17 PF13207.6 CAM45391.1 - 0.00083 19.8 0.2 0.33 11.4 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CAM45391.1 - 0.0012 18.4 0.0 0.63 9.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region NB-ARC PF00931.22 CAM45391.1 - 0.0014 17.9 0.0 0.79 8.8 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain Vps4_C PF09336.10 CAM45391.1 - 0.0015 18.5 0.0 0.0057 16.6 0.0 2.0 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain NTPase_1 PF03266.15 CAM45391.1 - 0.0015 18.5 0.1 0.24 11.3 0.0 2.8 2 0 0 2 2 2 1 NTPase ATPase_2 PF01637.18 CAM45391.1 - 0.0016 18.4 0.0 0.33 10.8 0.0 2.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Rad17 PF03215.15 CAM45391.1 - 0.0019 18.2 0.0 0.08 12.8 0.0 2.5 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_25 PF13481.6 CAM45391.1 - 0.0019 17.8 1.6 2.2 7.8 0.1 3.6 2 2 1 3 3 3 1 AAA domain AAA_19 PF13245.6 CAM45391.1 - 0.0022 18.4 0.0 1.9 8.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 CAM45391.1 - 0.0025 17.6 0.0 0.51 10.0 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Sigma54_activ_2 PF14532.6 CAM45391.1 - 0.004 17.3 0.0 0.047 13.8 0.0 2.6 3 0 0 3 3 3 1 Sigma-54 interaction domain Bac_DnaA PF00308.18 CAM45391.1 - 0.0043 16.9 0.0 1.8 8.4 0.0 2.6 2 0 0 2 2 2 1 Bacterial dnaA protein Parvo_NS1 PF01057.17 CAM45391.1 - 0.015 14.4 0.1 0.45 9.5 0.1 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 DUF815 PF05673.13 CAM45391.1 - 0.018 14.2 0.0 3.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 CAM45391.1 - 0.03 14.1 0.1 10 5.8 0.0 2.8 3 0 0 3 3 2 0 AAA domain TniB PF05621.11 CAM45391.1 - 0.034 13.5 0.0 8.7 5.7 0.0 3.1 3 0 0 3 3 3 0 Bacterial TniB protein ATPase PF06745.13 CAM45391.1 - 0.12 11.7 0.0 3.1 7.1 0.0 2.5 2 1 0 2 2 2 0 KaiC Aminotran_5 PF00266.19 CAM45392.1 - 4.5e-80 269.4 0.0 5.3e-80 269.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CAM45392.1 - 2e-08 33.9 0.0 3e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 CAM45392.1 - 0.00029 20.2 0.0 0.00048 19.6 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 CAM45392.1 - 0.076 11.7 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain AAA PF00004.29 CAM45393.2 - 1.5e-37 128.9 0.0 3.5e-27 95.4 0.0 3.5 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CAM45393.2 - 1.8e-12 47.7 1.1 0.00011 22.5 0.0 3.5 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CAM45393.2 - 3e-10 40.8 1.1 0.003 18.0 0.6 4.3 2 2 0 2 2 2 2 AAA ATPase domain Mg_chelatase PF01078.21 CAM45393.2 - 8e-08 31.9 0.0 0.00087 18.7 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 CAM45393.2 - 1.5e-07 31.7 0.0 0.00018 21.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CAM45393.2 - 4.2e-07 30.0 0.0 0.044 13.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CAM45393.2 - 4.6e-07 30.4 0.0 0.0021 18.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 CAM45393.2 - 5.2e-07 29.6 0.0 0.00062 19.5 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_33 PF13671.6 CAM45393.2 - 1e-06 29.0 0.0 0.037 14.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 CAM45393.2 - 1.3e-06 28.9 0.0 0.0051 17.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter TIP49 PF06068.13 CAM45393.2 - 1.5e-06 27.7 0.0 0.019 14.2 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_24 PF13479.6 CAM45393.2 - 3e-06 27.1 0.0 0.09 12.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 CAM45393.2 - 3.3e-05 23.7 0.3 0.012 15.3 0.0 2.9 3 0 0 3 3 2 1 AAA domain RuvB_N PF05496.12 CAM45393.2 - 3.9e-05 23.4 0.1 0.097 12.4 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 CAM45393.2 - 5.1e-05 23.0 0.0 0.00014 21.6 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RNA_helicase PF00910.22 CAM45393.2 - 8.3e-05 22.9 0.0 0.49 10.8 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 CAM45393.2 - 0.00011 22.5 1.3 0.031 14.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 CAM45393.2 - 0.00011 22.2 0.0 0.18 11.7 0.0 3.4 3 1 0 3 3 2 1 NACHT domain Sigma54_activat PF00158.26 CAM45393.2 - 0.00011 21.9 0.0 0.67 9.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.6 CAM45393.2 - 0.00012 22.5 0.1 1.2 9.4 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_7 PF12775.7 CAM45393.2 - 0.0002 20.9 0.0 0.25 10.9 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region NB-ARC PF00931.22 CAM45393.2 - 0.00025 20.3 0.1 0.29 10.3 0.0 3.0 2 1 1 3 3 3 1 NB-ARC domain AAA_17 PF13207.6 CAM45393.2 - 0.00027 21.4 0.0 0.3 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CAM45393.2 - 0.00029 20.7 0.0 0.43 10.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 CAM45393.2 - 0.00066 19.4 0.1 0.16 11.7 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Rad17 PF03215.15 CAM45393.2 - 0.00086 19.3 0.0 0.033 14.1 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain DUF2075 PF09848.9 CAM45393.2 - 0.0013 18.1 0.0 0.16 11.1 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 CAM45393.2 - 0.0013 18.8 0.0 0.13 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CAM45393.2 - 0.0019 17.8 0.6 2 7.9 0.2 3.8 3 1 1 4 4 4 1 AAA domain NTPase_1 PF03266.15 CAM45393.2 - 0.0032 17.4 0.1 0.33 10.9 0.1 2.8 2 0 0 2 2 2 1 NTPase TsaE PF02367.17 CAM45393.2 - 0.0036 17.3 0.0 3.9 7.5 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 CAM45393.2 - 0.0036 17.4 0.0 0.99 9.5 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain TniB PF05621.11 CAM45393.2 - 0.006 16.0 0.0 0.41 10.0 0.0 2.9 2 1 0 2 2 2 1 Bacterial TniB protein Adeno_IVa2 PF02456.15 CAM45393.2 - 0.019 13.8 0.0 4.2 6.1 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein ATPase_2 PF01637.18 CAM45393.2 - 0.026 14.5 0.0 3.1 7.6 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 CAM45393.2 - 0.049 13.7 0.0 0.24 11.5 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase Cytidylate_kin PF02224.18 CAM45393.2 - 0.071 12.8 0.0 0.29 10.8 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase KTI12 PF08433.10 CAM45393.2 - 0.076 12.5 0.0 11 5.3 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 ADP_ribosyl_GH PF03747.14 CAM45393.2 - 0.09 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase PhoH PF02562.16 CAM45393.2 - 0.1 12.0 0.0 8.1 5.8 0.1 2.3 2 0 0 2 2 2 0 PhoH-like protein T2SSE PF00437.20 CAM45393.2 - 0.11 11.6 0.1 0.96 8.4 0.2 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein Parvo_NS1 PF01057.17 CAM45393.2 - 0.11 11.6 0.0 5 6.1 0.0 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 PPV_E1_C PF00519.17 CAM45393.2 - 0.19 10.5 0.0 12 4.6 0.0 2.2 2 0 0 2 2 2 0 Papillomavirus helicase TPR_14 PF13428.6 CAM45394.1 - 4e-11 42.8 45.8 0.19 12.6 0.0 16.1 12 6 5 17 17 16 3 Tetratricopeptide repeat TPR_17 PF13431.6 CAM45394.1 - 1.2e-07 31.6 13.2 0.87 10.1 0.0 8.8 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_1 PF00515.28 CAM45394.1 - 1.6e-07 30.9 2.1 0.71 9.8 0.1 8.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 CAM45394.1 - 4.1e-06 26.5 21.0 40 4.7 0.4 12.3 14 0 0 14 14 14 0 Tetratricopeptide repeat TPR_7 PF13176.6 CAM45394.1 - 1e-05 25.2 9.9 3.8 7.8 0.2 8.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 CAM45394.1 - 4.1e-05 23.8 40.9 0.034 14.4 3.2 10.8 9 1 1 10 10 10 2 Tetratricopeptide repeat TPR_11 PF13414.6 CAM45394.1 - 0.00018 21.1 1.4 8.4 6.2 0.3 6.0 8 0 0 8 8 8 2 TPR repeat TPR_8 PF13181.6 CAM45394.1 - 0.00029 20.8 12.7 20 5.7 0.0 8.7 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_19 PF14559.6 CAM45394.1 - 0.0013 19.2 23.8 1.4 9.5 0.0 9.4 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_16 PF13432.6 CAM45394.1 - 0.037 14.7 0.2 0.037 14.7 0.2 10.1 10 1 1 11 11 11 0 Tetratricopeptide repeat Miga PF10265.9 CAM45394.1 - 0.11 11.4 0.2 4.8 6.0 0.2 2.4 2 0 0 2 2 2 0 Mitoguardin EBP PF05241.12 CAM45395.1 - 2.5e-11 43.4 7.4 3.1e-11 43.1 7.4 1.1 1 0 0 1 1 1 1 Emopamil binding protein DUF2781 PF10914.8 CAM45395.1 - 0.00011 22.6 10.3 0.00014 22.3 10.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) MRP PF09387.10 CAM45397.1 - 2.9e-46 157.9 0.4 2.9e-46 157.9 0.4 1.5 2 0 0 2 2 2 1 Mitochondrial RNA binding protein MRP WGG PF10273.9 CAM45398.1 - 0.0001 22.9 0.8 0.00023 21.7 0.8 1.6 1 1 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Glyco_transf_43 PF03360.16 CAM45398.1 - 0.0075 16.1 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 43 Virul_Fac PF10139.9 CAM45398.1 - 0.017 13.4 0.1 0.021 13.1 0.1 1.0 1 0 0 1 1 1 0 Putative bacterial virulence factor DUF5435 PF17503.2 CAM45398.1 - 0.027 14.2 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5435) TPR_16 PF13432.6 CAM45400.2 - 2.7e-28 98.3 20.6 1.1e-05 25.9 0.3 7.4 6 1 3 9 9 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 CAM45400.2 - 5.5e-23 79.8 44.9 6.5e-05 22.6 0.9 11.6 12 0 0 12 12 11 5 Tetratricopeptide repeat TPR_2 PF07719.17 CAM45400.2 - 6.7e-23 78.9 46.0 0.0011 18.9 0.3 11.9 12 0 0 12 12 11 6 Tetratricopeptide repeat TPR_19 PF14559.6 CAM45400.2 - 6.6e-20 71.4 25.0 2e-05 25.0 1.2 7.4 6 2 3 9 9 8 5 Tetratricopeptide repeat TPR_6 PF13174.6 CAM45400.2 - 8.8e-18 63.7 28.4 5.7e-05 23.5 0.0 10.8 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_7 PF13176.6 CAM45400.2 - 2.2e-16 58.6 25.4 0.038 14.0 0.0 10.0 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 CAM45400.2 - 3.6e-16 59.2 32.9 0.0001 22.5 0.2 9.0 7 4 1 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 CAM45400.2 - 1.1e-15 56.5 30.8 0.0086 16.2 0.4 10.2 12 0 0 12 12 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 CAM45400.2 - 2.3e-12 46.6 15.4 0.01 16.6 0.0 9.5 5 3 6 11 11 10 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CAM45400.2 - 1.6e-09 37.9 30.0 0.00085 19.5 0.4 7.3 5 2 4 9 9 9 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 CAM45400.2 - 1.8e-09 37.1 26.0 3.7e-06 26.5 1.3 7.8 10 1 0 10 10 8 3 TPR repeat TPR_9 PF13371.6 CAM45400.2 - 6e-07 29.5 5.2 0.018 15.1 0.0 5.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 CAM45400.2 - 1.8e-05 24.8 30.2 0.01 16.1 0.5 9.4 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_4 PF07721.14 CAM45400.2 - 0.00016 22.0 0.9 15 6.6 0.1 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF3808 PF10300.9 CAM45400.2 - 0.0002 20.3 4.7 0.00088 18.1 0.1 2.9 3 1 0 3 3 3 1 Protein of unknown function (DUF3808) DUF4919 PF16266.5 CAM45400.2 - 0.0017 18.3 4.3 0.17 11.8 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4919) PPR PF01535.20 CAM45400.2 - 0.0019 18.3 13.4 2.8 8.4 0.0 7.4 9 0 0 9 9 6 2 PPR repeat TPR_21 PF09976.9 CAM45400.2 - 0.0068 16.1 2.9 0.0068 16.1 2.9 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat-like domain 23S_rRNA_IVP PF05635.11 CAM45400.2 - 0.17 12.2 3.1 5.3 7.4 0.1 3.9 4 0 0 4 4 3 0 23S rRNA-intervening sequence protein DUF2989 PF11207.8 CAM45400.2 - 0.2 11.4 8.7 0.1 12.4 2.1 3.4 2 2 4 6 6 6 0 Protein of unknown function (DUF2989) DUF3856 PF12968.7 CAM45400.2 - 0.65 10.1 4.6 7.8 6.6 0.3 3.6 3 2 0 3 3 3 0 Domain of Unknown Function (DUF3856) Sel1 PF08238.12 CAM45400.2 - 1.3 9.8 18.5 5.6 7.8 0.1 7.3 7 1 1 8 8 6 0 Sel1 repeat TPR_10 PF13374.6 CAM45400.2 - 1.6 8.7 32.2 17 5.5 0.1 9.0 11 0 0 11 11 9 0 Tetratricopeptide repeat DUF3837 PF12939.7 CAM45400.2 - 1.9 8.9 5.6 2.9 8.3 0.1 3.8 5 0 0 5 5 3 0 Domain of unknown function (DUF3837) DUF2225 PF09986.9 CAM45400.2 - 2.4 7.9 25.1 1.5 8.5 6.3 5.6 2 2 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) Fis1_TPR_C PF14853.6 CAM45400.2 - 3.3 7.9 25.0 1.8 8.7 0.2 6.6 7 1 1 8 8 6 0 Fis1 C-terminal tetratricopeptide repeat JmjC PF02373.22 CAM45402.1 - 1.2e-10 41.8 4.8 5.8e-09 36.4 4.8 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 CAM45402.1 - 0.00032 20.5 0.0 0.023 14.4 0.0 2.7 2 1 0 2 2 2 2 Cupin-like domain RAI16-like PF10257.9 CAM45403.1 - 1.2e-08 34.3 0.5 0.00014 20.9 0.0 3.4 2 1 1 3 3 3 2 Retinoic acid induced 16-like protein eIF-1a PF01176.19 CAM45404.1 - 0.04 13.7 0.0 0.1 12.4 0.0 1.6 2 0 0 2 2 2 0 Translation initiation factor 1A / IF-1 SpoIIE PF07228.12 CAM45405.2 - 6e-05 23.0 2.4 0.05 13.5 1.6 3.1 1 1 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) HC2 PF07382.11 CAM45406.1 - 0.31 11.1 82.5 0.52 10.4 82.6 1.4 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 zf-RING_2 PF13639.6 CAM45407.2 - 4e-08 33.4 15.2 7.2e-08 32.6 15.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CAM45407.2 - 6.3e-08 32.8 10.8 1.3e-07 31.8 10.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CAM45407.2 - 1.5e-05 24.9 5.7 3.3e-05 23.8 5.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 CAM45407.2 - 6.1e-05 22.8 12.6 0.00011 21.9 12.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CAM45407.2 - 0.00011 22.1 8.8 0.00024 21.1 8.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 CAM45407.2 - 0.00016 21.3 10.0 0.00033 20.3 10.0 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 CAM45407.2 - 0.0023 17.8 11.3 0.0046 16.8 11.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CAM45407.2 - 0.019 14.9 12.5 0.036 14.0 12.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CAM45407.2 - 0.15 12.0 10.8 0.26 11.2 10.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) IF-2B PF01008.17 CAM45408.1 - 8.8e-34 117.0 0.0 1.7e-33 116.1 0.0 1.6 1 0 0 1 1 1 1 Initiation factor 2 subunit family Secretin_N_2 PF07655.13 CAM45409.2 - 0.17 12.5 1.8 0.4 11.3 0.2 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain HC2 PF07382.11 CAM45411.1 - 0.84 9.7 69.3 0.99 9.4 68.3 1.5 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Uso1_p115_C PF04871.13 CAM45411.1 - 5.7 7.3 15.7 6.7 7.1 15.7 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region WD40 PF00400.32 CAM45413.1 - 1.3e-16 60.6 15.3 0.00088 20.1 0.4 5.7 4 1 1 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAM45413.1 - 0.00017 21.8 0.1 0.54 10.6 0.0 3.7 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Cpn60_TCP1 PF00118.24 CAM45414.1 - 6.1e-147 490.2 12.0 7e-147 490.0 12.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF5442 PF17514.2 CAM45414.1 - 0.31 11.3 1.4 0.54 10.5 0.2 2.0 3 0 0 3 3 3 0 Family of unknown function (DUF5442) Cation_efflux PF01545.21 CAM45415.1 - 1.4e-42 145.7 13.7 1.4e-42 145.7 13.7 3.1 3 1 0 3 3 3 1 Cation efflux family UCH PF00443.29 CAM45416.1 - 4.1e-49 167.4 1.3 6.5e-49 166.7 1.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CAM45416.1 - 6e-16 58.9 4.6 6e-16 58.9 4.6 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DZR PF12773.7 CAM45416.1 - 0.067 13.2 6.5 0.49 10.5 6.5 2.2 1 1 0 1 1 1 0 Double zinc ribbon PhnA_Zn_Ribbon PF08274.12 CAM45416.1 - 0.96 9.5 4.4 3 7.9 0.3 2.5 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zinc_ribbon_10 PF10058.9 CAM45416.1 - 2.8 7.7 7.2 5.1 6.9 0.3 3.0 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein zinc-ribbons_6 PF07191.12 CAM45416.1 - 3 7.9 5.8 9 6.4 4.2 2.4 1 1 1 2 2 2 0 zinc-ribbons zf-ribbon_3 PF13248.6 CAM45416.1 - 3.4 7.2 4.8 8.1 6.0 0.5 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-TFIIB PF13453.6 CAM45416.1 - 4.7 6.6 4.8 18 4.8 0.6 3.1 3 0 0 3 3 3 0 Transcription factor zinc-finger Ribonucleas_3_3 PF14622.6 CAM45418.1 - 9.7e-06 25.8 0.0 0.00012 22.3 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease-III-like LRR_6 PF13516.6 CAM45419.1 - 5.8e-17 60.2 20.1 0.0032 17.4 0.0 9.5 9 0 0 9 9 9 7 Leucine Rich repeat LRR_1 PF00560.33 CAM45419.1 - 2.2e-08 33.5 2.2 3.7 8.5 0.4 7.5 8 1 0 8 8 8 1 Leucine Rich Repeat LRR_8 PF13855.6 CAM45419.1 - 6.6e-06 25.8 1.7 0.023 14.5 0.8 5.3 4 2 0 4 4 4 1 Leucine rich repeat LRR_4 PF12799.7 CAM45419.1 - 7.7e-06 26.2 5.0 0.24 11.9 0.2 5.2 5 1 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CAM45419.1 - 0.12 11.9 0.0 0.55 9.7 0.0 2.1 2 0 0 2 2 2 0 Leucine-rich repeat KH_1 PF00013.29 CAM45421.1 - 1.1e-07 31.5 0.0 2.5e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 KH domain zf-CCCH_4 PF18044.1 CAM45421.1 - 3e-07 30.1 4.4 6.1e-07 29.1 4.4 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger Helicase_C PF00271.31 CAM45421.1 - 0.00024 21.4 0.3 0.00065 20.0 0.3 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain zf-CCCH PF00642.24 CAM45421.1 - 0.001 18.9 2.9 0.0029 17.5 2.9 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CAM45421.1 - 0.0092 16.0 2.0 0.022 14.8 2.0 1.7 1 0 0 1 1 1 1 Zinc finger domain tRNA-synt_1d PF00750.19 CAM45422.1 - 7.8e-110 367.1 0.2 9.7e-66 222.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.15 CAM45422.1 - 9.2e-27 93.6 3.5 6.1e-26 90.9 0.8 2.7 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 CAM45422.1 - 1.9e-13 50.8 0.2 8.2e-13 48.8 0.2 2.2 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain Cupin_8 PF13621.6 CAM45423.2 - 7.7e-18 65.1 1.0 5.3e-17 62.4 0.1 2.6 1 1 1 2 2 2 1 Cupin-like domain JmjC PF02373.22 CAM45423.2 - 2e-11 44.3 0.0 4.4e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 CAM45423.2 - 1.7e-05 24.5 0.0 3.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein F-box PF00646.33 CAM45423.2 - 0.0014 18.4 0.3 0.0056 16.5 0.3 1.9 2 0 0 2 2 2 1 F-box domain Cupin_2 PF07883.11 CAM45423.2 - 0.014 15.1 0.0 0.04 13.6 0.0 1.7 1 0 0 1 1 1 0 Cupin domain F-box-like PF12937.7 CAM45423.2 - 0.066 13.1 0.5 0.17 11.8 0.5 1.6 1 0 0 1 1 1 0 F-box-like MAGE_N PF12440.8 CAM45423.2 - 6.9 7.4 9.1 17 6.1 0.2 2.5 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal NRDD PF13597.6 CAM45426.1 - 0.11 11.2 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase Rho_GDI PF02115.17 CAM45426.1 - 0.3 10.8 0.8 0.38 10.5 0.1 1.5 2 0 0 2 2 2 0 RHO protein GDP dissociation inhibitor Ferritin-like PF12902.7 CAM45427.1 - 1.9 8.3 13.7 0.17 11.7 8.0 2.1 1 1 1 2 2 2 0 Ferritin-like Pkinase PF00069.25 CAM45428.2 - 4.4e-60 203.3 0.0 6.5e-60 202.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM45428.2 - 3e-42 144.7 0.0 4.9e-42 144.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CAM45428.2 - 0.0041 17.1 0.0 0.016 15.1 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CAM45428.2 - 0.022 13.5 0.0 0.13 11.0 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase RIO1 PF01163.22 CAM45428.2 - 0.098 12.2 0.0 0.43 10.2 0.0 1.9 1 1 1 2 2 2 0 RIO1 family Kinase-like PF14531.6 CAM45428.2 - 0.18 11.1 0.0 0.81 8.9 0.0 1.8 2 0 0 2 2 2 0 Kinase-like RL10P_insert PF17777.1 CAM45429.1 - 1.4e-20 73.0 0.2 2.5e-20 72.2 0.2 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 CAM45429.1 - 8.4e-18 64.4 0.1 2.1e-17 63.1 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 CAM45429.1 - 9.5e-12 45.4 5.8 9.5e-12 45.4 5.8 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein DUF3479 PF11965.8 CAM45429.1 - 0.089 12.9 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3479) RL10P_insert PF17777.1 CAM45430.1 - 1.5e-20 73.0 0.2 2.5e-20 72.2 0.2 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 CAM45430.1 - 1e-17 64.1 0.1 2.5e-17 62.8 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 CAM45430.1 - 9.5e-12 45.4 5.8 9.5e-12 45.4 5.8 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein DUF3479 PF11965.8 CAM45430.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3479) DUF1719 PF08224.11 CAM45431.1 - 0.017 14.3 0.0 0.021 13.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1719) Choline_kinase PF01633.20 CAM45433.1 - 1.1e-21 77.4 0.3 1.9e-20 73.4 0.3 2.1 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CAM45433.1 - 4.3e-10 39.9 0.1 1.8e-09 37.9 0.1 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 CAM45433.1 - 0.012 15.0 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain AlbA_2 PF04326.14 CAM45434.2 - 0.0004 20.7 0.0 0.00072 19.9 0.0 1.5 1 0 0 1 1 1 1 Putative DNA-binding domain Snf7 PF03357.21 CAM45435.1 - 2.4e-32 111.9 33.2 2.4e-32 111.9 33.2 1.5 1 1 1 2 2 2 1 Snf7 Arg_decarbox_C PF17944.1 CAM45435.1 - 1.3 9.6 6.0 7.5 7.2 0.6 3.3 3 1 1 4 4 4 0 Arginine decarboxylase C-terminal helical extension CBF PF03914.17 CAM45436.1 - 7.3e-33 114.0 1.9 7.3e-33 114.0 1.9 2.0 2 0 0 2 2 2 1 CBF/Mak21 family PCI PF01399.27 CAM45437.1 - 1.8e-18 66.9 0.1 3.5e-18 66.0 0.1 1.5 1 0 0 1 1 1 1 PCI domain Rpn3_C PF08375.11 CAM45437.1 - 1.5e-15 57.3 0.9 1.5e-15 57.3 0.9 2.0 3 0 0 3 3 3 1 Proteasome regulatory subunit C-terminal TPR_2 PF07719.17 CAM45437.1 - 0.075 13.2 0.8 0.22 11.7 0.8 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat cNMP_binding PF00027.29 CAM45438.2 - 1.6e-13 50.5 0.4 0.0002 21.4 0.0 4.7 3 2 1 4 4 4 3 Cyclic nucleotide-binding domain SPX PF03105.19 CAM45439.1 - 0.013 15.5 1.1 0.021 14.8 1.1 1.3 1 0 0 1 1 1 0 SPX domain COG5 PF10392.9 CAM45439.1 - 0.014 15.6 0.3 0.033 14.3 0.3 1.6 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Spatacsin_C PF14649.6 CAM45439.1 - 0.16 11.0 0.7 0.24 10.5 0.7 1.2 1 0 0 1 1 1 0 Spatacsin C-terminus Rrn6 PF10214.9 CAM45439.1 - 6.4 5.1 7.4 0.44 9.0 2.5 1.5 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor Peptidase_M3 PF01432.20 CAM45441.1 - 1.8e-127 426.4 0.0 2.2e-127 426.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 CAM45441.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Peptidase_M3 PF01432.20 CAM45442.1 - 6.6e-126 421.2 0.0 7.7e-126 421.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 CAM45442.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like DUF3093 PF11292.8 CAM45443.2 - 0.074 13.3 6.2 1.9 8.7 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) AroM PF07302.11 CAM45444.1 - 0.0025 17.2 0.1 0.0056 16.1 0.1 1.5 1 0 0 1 1 1 1 AroM protein DUF543 PF04418.12 CAM45445.1 - 4.3e-22 77.9 0.0 5.7e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) TctA PF01970.16 CAM45445.1 - 0.044 12.5 0.1 0.093 11.4 0.0 1.5 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctA family RNA_pol_L_2 PF13656.6 CAM45446.1 - 2.5e-22 78.4 0.0 3.4e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CAM45446.1 - 1.7e-05 24.2 0.0 3.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DAGAT PF03982.13 CAM45447.1 - 4.4e-34 117.8 0.0 7.3e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Aa_trans PF01490.18 CAM45449.1 - 5.4e-58 196.6 28.0 6.2e-58 196.4 28.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CAM45449.1 - 1.3e-10 40.9 7.1 1.3e-10 40.9 7.1 1.6 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family DUF4231 PF14015.6 CAM45449.1 - 0.76 10.3 9.4 4.1 7.9 0.3 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) HC2 PF07382.11 CAM45451.1 - 0.08 13.0 43.1 0.086 12.9 43.1 1.0 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 IF4E PF01652.18 CAM45452.1 - 9.5e-45 152.2 0.4 1.1e-44 152.0 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E WD40 PF00400.32 CAM45453.2 - 1.4e-06 28.9 3.9 9 7.4 0.1 6.3 6 1 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.11 CAM45453.2 - 0.091 12.6 0.0 2 8.3 0.0 2.8 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A BRO1 PF03097.18 CAM45454.1 - 2.1e-58 198.0 1.7 2.1e-58 198.0 1.7 1.9 2 1 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 CAM45454.1 - 1e-29 103.8 9.5 1e-29 103.8 9.5 2.5 1 1 1 2 2 2 1 ALIX V-shaped domain binding to HIV DHHA2 PF02833.14 CAM45454.1 - 0.058 13.6 1.7 12 6.1 0.1 3.8 4 0 0 4 4 4 0 DHHA2 domain DUF1405 PF07187.11 CAM45454.1 - 0.074 13.0 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1405) MIT PF04212.18 CAM45454.1 - 0.11 12.6 0.0 0.11 12.6 0.0 3.7 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 CAM45454.1 - 0.13 12.1 0.9 0.37 10.7 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Pex14_N PF04695.13 CAM45454.1 - 0.43 11.2 15.2 1.5 9.4 15.2 2.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Cob_adeno_trans PF01923.18 CAM45454.1 - 3.3 7.8 12.2 0.086 13.0 2.4 3.2 2 2 1 3 3 3 0 Cobalamin adenosyltransferase V-ATPase_G_2 PF16999.5 CAM45455.1 - 9.9 6.6 12.2 14 6.1 1.3 3.9 3 0 0 3 3 3 0 Vacuolar (H+)-ATPase G subunit ThiF PF00899.21 CAM45457.1 - 5.3e-62 209.4 0.0 8.2e-62 208.7 0.0 1.2 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 CAM45457.1 - 5.7e-06 26.8 0.0 2.5e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain Sacchrp_dh_NADP PF03435.18 CAM45457.1 - 0.0014 18.9 0.3 0.0032 17.7 0.3 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 CAM45457.1 - 0.025 14.7 0.1 0.13 12.3 0.1 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pea-VEAacid PF08111.11 CAM45457.1 - 0.038 14.3 0.0 0.092 13.1 0.0 1.7 1 0 0 1 1 1 0 Pea-VEAacid family 3HCDH_N PF02737.18 CAM45457.1 - 0.09 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 CAM45457.1 - 0.13 11.8 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain OAM_alpha PF16552.5 CAM45457.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 D-ornithine 4,5-aminomutase alpha-subunit LRR_9 PF14580.6 CAM45459.1 - 0.003 17.1 0.0 0.0061 16.1 0.0 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CAM45460.1 - 0.00026 21.3 0.3 0.00067 20.0 0.3 1.7 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM45460.1 - 0.0027 17.4 2.0 0.01 15.6 2.0 2.0 1 1 0 1 1 1 1 Leucine rich repeat LRR_9 PF14580.6 CAM45460.1 - 0.0045 16.5 0.0 0.0095 15.5 0.0 1.5 1 0 0 1 1 1 1 Leucine-rich repeat zf_CCCH_4 PF18345.1 CAM45460.1 - 0.016 15.2 1.1 0.1 12.7 1.1 2.3 1 1 0 1 1 1 0 Zinc finger domain zf-CCCH PF00642.24 CAM45460.1 - 0.044 13.7 2.4 0.085 12.8 2.4 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 CAM45460.1 - 0.046 14.2 3.1 0.1 13.1 3.1 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger LRR_6 PF13516.6 CAM45460.1 - 0.052 13.6 0.3 2.5 8.4 0.1 2.8 2 0 0 2 2 2 0 Leucine Rich repeat zf-CCCH_4 PF18044.1 CAM45460.1 - 0.16 11.8 2.0 0.43 10.4 2.0 1.8 1 0 0 1 1 1 0 CCCH-type zinc finger ABC2_membrane PF01061.24 CAM45461.1 - 0.00062 19.2 14.7 0.00062 19.2 14.7 2.0 2 0 0 2 2 2 1 ABC-2 type transporter HpaP PF09483.10 CAM45461.1 - 0.12 12.7 0.4 5 7.4 0.0 2.4 2 0 0 2 2 2 0 Type III secretion protein (HpaP) ABC_tran PF00005.27 CAM45461.1 - 0.17 12.4 0.0 0.32 11.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Metal_resist PF13801.6 CAM45461.1 - 1.2 9.4 5.3 0.35 11.1 0.9 2.4 2 0 0 2 2 2 0 Heavy-metal resistance eRF1_2 PF03464.15 CAM45462.1 - 2.4e-41 141.2 0.0 4.5e-41 140.3 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CAM45462.1 - 6.6e-37 126.5 1.5 1.1e-36 125.7 0.3 2.0 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.15 CAM45462.1 - 2e-12 47.2 0.0 3.3e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 CAM45462.1 - 6.1e-09 36.3 0.0 9.5e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 CAM45462.1 - 8e-09 35.9 0.0 1.4e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 Fer2_3 PF13085.6 CAM45463.1 - 0.017 15.1 0.2 0.046 13.7 0.2 1.7 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Vps5 PF09325.10 CAM45463.1 - 0.026 14.1 8.0 0.29 10.6 8.0 2.2 1 1 0 1 1 1 0 Vps5 C terminal like Big_10 PF17964.1 CAM45463.1 - 0.13 12.2 1.8 0.24 11.4 1.8 1.4 1 0 0 1 1 1 0 Bacterial Ig domain ALMT PF11744.8 CAM45463.1 - 0.6 8.9 4.7 0.37 9.6 2.8 1.5 1 1 0 1 1 1 0 Aluminium activated malate transporter STAT_alpha PF01017.20 CAM45463.1 - 1.1 9.1 4.5 1.1 9.2 2.7 1.9 2 0 0 2 2 2 0 STAT protein, all-alpha domain DHR10 PF18595.1 CAM45463.1 - 3.5 7.7 11.0 0.15 12.1 2.3 2.8 3 1 1 4 4 4 0 Designed helical repeat protein 10 domain DUF2203 PF09969.9 CAM45463.1 - 3.6 8.3 5.0 5.1 7.9 2.0 2.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) GAS PF13851.6 CAM45463.1 - 4.5 6.6 14.8 1.3 8.4 7.6 2.7 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding AAA_6 PF12774.7 CAM45464.1 - 2.1e-124 414.8 0.0 3.8e-124 413.9 0.0 1.5 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CAM45464.1 - 6.3e-110 368.0 2.7 6.3e-110 368.0 2.7 4.1 4 0 0 4 4 3 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 CAM45464.1 - 1.2e-60 204.4 2.0 1.2e-60 204.4 2.0 2.5 2 0 0 2 2 1 1 ATP-binding dynein motor region AAA_8 PF12780.7 CAM45464.1 - 1.8e-47 161.8 0.1 2.8e-46 158.0 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_lid_11 PF18198.1 CAM45464.1 - 1.1e-30 106.6 0.0 2.8e-30 105.3 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_7 PF12775.7 CAM45464.1 - 1.4e-30 106.2 0.0 2.1e-24 86.0 0.0 4.4 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_5 PF07728.14 CAM45464.1 - 2.2e-30 105.5 0.0 3.6e-19 69.1 0.0 5.8 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 CAM45464.1 - 1e-25 90.1 0.1 7.4e-25 87.4 0.0 2.7 3 0 0 3 3 1 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 CAM45464.1 - 4.6e-25 88.4 3.7 9.5e-25 87.3 3.7 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_C PF18199.1 CAM45464.1 - 3.1e-22 79.2 0.0 3.1e-22 79.2 0.0 2.4 3 0 0 3 3 2 1 Dynein heavy chain C-terminal domain AAA_16 PF13191.6 CAM45464.1 - 1.3e-14 54.9 5.3 0.00078 19.9 0.0 7.3 6 1 1 7 7 6 2 AAA ATPase domain AAA_22 PF13401.6 CAM45464.1 - 7.3e-11 42.5 0.2 0.11 12.8 0.0 6.3 5 0 0 5 5 5 2 AAA domain AAA PF00004.29 CAM45464.1 - 1.1e-09 38.8 0.1 0.17 12.3 0.0 6.3 6 0 0 6 6 5 2 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 CAM45464.1 - 2.6e-06 28.0 0.1 0.0012 19.4 0.0 4.4 3 0 0 3 3 3 1 ABC transporter RsgA_GTPase PF03193.16 CAM45464.1 - 5.3e-06 26.4 3.5 0.00043 20.2 0.0 4.0 3 0 0 3 3 3 1 RsgA GTPase RNA_helicase PF00910.22 CAM45464.1 - 1.9e-05 25.0 0.0 1.7 9.0 0.0 4.9 5 0 0 5 5 5 1 RNA helicase AAA_29 PF13555.6 CAM45464.1 - 3.7e-05 23.4 0.1 0.025 14.3 0.0 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_30 PF13604.6 CAM45464.1 - 6.6e-05 22.7 0.2 0.04 13.6 0.0 3.2 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CAM45464.1 - 7.6e-05 22.5 0.1 0.12 12.1 0.0 3.4 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 CAM45464.1 - 0.00044 20.8 0.1 0.15 12.6 0.0 4.0 4 0 0 4 4 2 1 AAA domain AAA_33 PF13671.6 CAM45464.1 - 0.0024 18.1 0.2 0.13 12.4 0.0 4.1 4 0 0 4 4 4 1 AAA domain Rad17 PF03215.15 CAM45464.1 - 0.0055 16.6 0.3 1.3 9.0 0.0 3.6 3 0 0 3 3 3 1 Rad17 P-loop domain T2SSE PF00437.20 CAM45464.1 - 0.0061 15.7 0.0 0.028 13.5 0.0 2.1 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_21 PF13304.6 CAM45464.1 - 0.0087 15.9 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 CAM45464.1 - 0.051 13.8 0.0 0.051 13.8 0.0 4.1 5 0 0 5 5 2 0 AAA domain Zeta_toxin PF06414.12 CAM45464.1 - 0.051 12.9 0.2 1.9 7.7 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin ATPase_2 PF01637.18 CAM45464.1 - 0.078 12.9 5.8 0.62 9.9 0.0 3.5 4 0 0 4 4 2 0 ATPase domain predominantly from Archaea PhoH PF02562.16 CAM45464.1 - 0.13 11.7 1.5 0.6 9.5 0.0 2.7 4 0 0 4 4 2 0 PhoH-like protein TsaE PF02367.17 CAM45464.1 - 0.17 11.9 0.1 2.4 8.1 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP_bind_1 PF03029.17 CAM45464.1 - 0.24 11.2 1.9 6.5 6.4 0.0 3.5 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein TMPIT PF07851.13 CAM45464.1 - 0.85 8.8 22.4 0.054 12.7 0.7 3.5 3 0 0 3 3 3 0 TMPIT-like protein RPW8 PF05659.11 CAM45464.1 - 0.9 9.2 12.2 1.2 8.9 0.1 4.7 4 0 0 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 NACHT PF05729.12 CAM45464.1 - 6.7 6.6 5.9 3.8 7.4 0.1 3.6 4 0 0 4 4 2 0 NACHT domain DUF948 PF06103.11 CAM45464.1 - 7.2 6.9 9.3 47 4.3 3.5 5.0 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) TBCC PF07986.12 CAM45465.1 - 3.1e-25 88.3 5.7 7.7e-19 67.6 7.5 2.4 2 0 0 2 2 2 2 Tubulin binding cofactor C Init_tRNA_PT PF04179.12 CAM45465.1 - 0.14 12.5 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain ComX PF05952.12 CAM45465.1 - 0.16 11.9 0.0 3.4 7.7 0.0 2.3 1 1 1 2 2 2 0 Bacillus competence pheromone ComX CAP_C PF08603.11 CAM45465.1 - 0.6 9.7 2.2 1.1 8.8 2.2 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal Pkinase PF00069.25 CAM45467.1 - 9.9e-23 80.8 0.0 5.4e-20 71.9 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM45467.1 - 3.4e-10 39.6 0.0 5.1e-09 35.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAM45467.1 - 8.3e-08 31.4 0.1 1.1e-07 31.0 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CAM45467.1 - 0.00018 21.0 0.2 0.00029 20.2 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CAM45467.1 - 0.00047 20.2 0.1 0.001 19.0 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CAM45467.1 - 0.0011 18.6 0.3 0.003 17.2 0.1 1.7 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 CAM45467.1 - 0.047 13.3 0.1 0.1 12.2 0.1 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase IFRD PF05004.13 CAM45468.2 - 0.037 13.2 0.3 0.065 12.3 0.3 1.4 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) Lzipper-MIP1 PF14389.6 CAM45468.2 - 1 9.7 11.5 6.8 7.1 0.7 2.8 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 PEPCK_ATP PF01293.20 CAM45469.1 - 3.7e-194 645.7 0.0 4.6e-194 645.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase DUF4914 PF16260.5 CAM45469.1 - 0.044 11.9 0.2 0.21 9.7 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4914) AAA_33 PF13671.6 CAM45469.1 - 0.14 12.3 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain PEPCK_ATP PF01293.20 CAM45470.1 - 1.1e-13 50.7 0.0 1.4e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase CBFD_NFYB_HMF PF00808.23 CAM45470.1 - 0.16 12.3 0.3 0.22 11.8 0.3 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PEPCK_ATP PF01293.20 CAM45471.1 - 2.8e-46 158.2 0.0 3.4e-46 157.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase PEPCK_ATP PF01293.20 CAM45472.1 - 9e-61 206.0 0.0 1.1e-60 205.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase DUF4407 PF14362.6 CAM45473.2 - 0.0007 19.0 10.8 0.0007 19.0 10.8 13.9 4 1 9 13 13 13 2 Domain of unknown function (DUF4407) Apo-CII PF05355.11 CAM45473.2 - 0.18 12.0 3.7 89 3.3 0.1 3.9 3 0 0 3 3 3 0 Apolipoprotein C-II Sas6_CC PF18594.1 CAM45473.2 - 0.2 11.4 9.0 8.8 6.2 0.1 6.4 5 0 0 5 5 5 0 Sas6/XLF/XRCC4 coiled-coil domain DUF4072 PF13284.6 CAM45473.2 - 0.37 11.3 31.5 10 6.7 4.9 5.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4072) MarR PF01047.22 CAM45473.2 - 0.79 9.7 18.6 18 5.3 0.1 6.4 6 0 0 6 6 6 0 MarR family YchF-GTPase_C PF06071.13 CAM45474.1 - 5.1e-24 84.3 0.1 1.2e-23 83.0 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 CAM45474.1 - 3.6e-21 75.4 0.0 7.7e-21 74.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CAM45474.1 - 2.9e-07 30.2 0.0 6.3e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 CAM45474.1 - 0.0018 18.3 0.0 0.0036 17.3 0.0 1.5 1 0 0 1 1 1 1 TGS domain ICA69 PF04629.14 CAM45474.1 - 0.052 13.9 0.2 0.081 13.2 0.2 1.2 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain MeaB PF03308.16 CAM45474.1 - 0.095 11.7 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 CAM45474.1 - 0.17 12.4 0.0 0.37 11.3 0.0 1.8 1 1 0 1 1 1 0 ABC transporter DSPc PF00782.20 CAM45475.2 - 2e-25 89.1 0.0 3.2e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CAM45475.2 - 0.00053 19.6 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Gelsolin PF00626.22 CAM45475.2 - 0.046 13.6 0.0 0.23 11.4 0.0 2.1 2 0 0 2 2 2 0 Gelsolin repeat Flagellar_rod PF05149.12 CAM45476.1 - 6e-105 350.8 21.3 1.4e-104 349.6 21.3 1.7 1 0 0 1 1 1 1 Paraflagellar rod protein SH3_9 PF14604.6 CAM45476.1 - 1.1e-11 44.4 0.0 2.4e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CAM45476.1 - 1.5e-11 43.7 0.0 2.7e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CAM45476.1 - 7.7e-09 35.1 0.0 1.4e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Mlp PF03304.13 CAM45476.1 - 0.0057 16.9 7.8 0.31 11.3 3.7 2.8 2 1 0 2 2 2 2 Mlp lipoprotein family RRT14 PF17075.5 CAM45476.1 - 0.37 10.9 6.1 0.15 12.2 2.5 2.2 2 0 0 2 2 2 0 Regular of rDNA transcription protein 14 Cnl2_NKP2 PF09447.10 CAM45476.1 - 6.1 7.1 7.3 1.1 9.4 0.8 3.2 4 0 0 4 4 4 0 Cnl2/NKP2 family protein GSP_synth PF03738.14 CAM45478.1 - 2.8e-71 240.7 0.0 3.7e-71 240.3 0.0 1.1 1 0 0 1 1 1 1 Glutathionylspermidine synthase preATP-grasp CHAP PF05257.16 CAM45478.1 - 5.9e-10 39.6 0.1 1.4e-09 38.4 0.1 1.7 1 0 0 1 1 1 1 CHAP domain YCII PF03795.14 CAM45479.1 - 0.1 13.0 0.1 0.24 11.8 0.1 1.6 1 0 0 1 1 1 0 YCII-related domain Mre11_DNA_bind PF04152.14 CAM45480.1 - 4.3e-26 92.2 0.0 1.3e-25 90.7 0.0 1.8 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 CAM45480.1 - 6.4e-14 52.9 0.2 1.2e-13 52.0 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PSD5 PF07637.11 CAM45481.1 - 0.022 15.1 0.7 0.12 12.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1595) bZIP_2 PF07716.15 CAM45481.1 - 0.032 14.3 0.9 0.087 12.9 0.9 1.7 1 0 0 1 1 1 0 Basic region leucine zipper DICT PF10069.9 CAM45481.1 - 0.032 14.0 0.2 0.69 9.7 0.1 2.4 2 0 0 2 2 2 0 Sensory domain in DIguanylate Cyclases and Two-component system TM1586_NiRdase PF14512.6 CAM45483.1 - 0.048 13.2 0.1 0.078 12.5 0.1 1.5 1 1 0 1 1 1 0 Putative TM nitroreductase DUF3611 PF12263.8 CAM45485.1 - 0.017 15.1 0.1 0.017 15.1 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) Amastin PF07344.11 CAM45485.1 - 0.022 14.6 0.0 0.051 13.4 0.0 1.6 1 1 0 1 1 1 0 Amastin surface glycoprotein 7TM_GPCR_Srv PF10323.9 CAM45485.1 - 0.11 11.9 4.7 0.15 11.4 3.2 1.8 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv Pkinase PF00069.25 CAM45487.1 - 3.1e-44 151.3 0.0 8.9e-41 140.0 0.0 3.0 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM45487.1 - 1.2e-22 80.4 0.0 2.6e-21 76.1 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM45487.1 - 9.4e-08 31.7 0.0 1.6e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CAM45487.1 - 0.0002 20.5 0.0 0.0003 19.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CAM45487.1 - 0.11 11.2 0.0 0.2 10.4 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase DUF908 PF06012.12 CAM45487.1 - 0.97 8.8 4.7 2.6 7.4 4.7 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) SPX PF03105.19 CAM45487.1 - 5.6 6.8 10.9 0.51 10.2 5.3 2.0 2 0 0 2 2 2 0 SPX domain Dpy-30 PF05186.13 CAM45488.2 - 0.0014 18.3 0.0 0.0029 17.3 0.0 1.5 1 0 0 1 1 1 1 Dpy-30 motif Hydin_ADK PF17213.3 CAM45488.2 - 0.035 14.4 0.2 0.035 14.4 0.2 2.9 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain Selenoprotein_S PF06936.11 CAM45488.2 - 0.9 9.3 8.5 0.19 11.6 4.8 1.7 2 0 0 2 2 2 0 Selenoprotein S (SelS) IFT43 PF15305.6 CAM45489.2 - 6.7e-06 26.3 0.4 1.8e-05 25.0 0.4 1.7 1 0 0 1 1 1 1 Intraflagellar transport protein 43 LSM PF01423.22 CAM45490.1 - 1.4e-17 63.2 0.4 1.7e-17 62.9 0.4 1.1 1 0 0 1 1 1 1 LSM domain Peptidase_C2 PF00648.21 CAM45491.2 - 3.4e-35 121.5 0.0 5.6e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 CAM45491.2 - 2.8e-07 30.9 0.0 5.3e-06 26.7 0.0 2.9 2 0 0 2 2 2 1 Calpain large subunit, domain III Sec16_N PF12935.7 CAM45491.2 - 0.0001 22.5 0.3 0.37 10.9 0.0 5.2 5 0 0 5 5 5 1 Vesicle coat trafficking protein Sec16 N-terminus Thioredoxin_6 PF13848.6 CAM45491.2 - 0.17 11.8 0.0 1.4e+02 2.3 0.0 3.4 3 0 0 3 3 3 0 Thioredoxin-like domain Fib_alpha PF08702.10 CAM45491.2 - 0.5 10.5 16.2 31 4.7 2.6 7.7 6 1 1 7 7 7 0 Fibrinogen alpha/beta chain family L27 PF02828.16 CAM45491.2 - 5 7.0 13.6 93 2.9 0.1 6.4 6 0 0 6 6 6 0 L27 domain Pox_A_type_inc PF04508.12 CAM45492.1 - 0.11 12.3 3.8 0.17 11.8 3.8 1.3 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat TMV_coat PF00721.21 CAM45492.1 - 0.19 11.5 1.1 0.37 10.6 1.1 1.6 1 1 0 1 1 1 0 Virus coat protein (TMV like) Herpes_BLLF1 PF05109.13 CAM45492.1 - 0.31 9.0 8.6 0.35 8.8 8.6 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Suf PF05843.14 CAM45492.1 - 1.6 8.6 8.1 1.7 8.6 8.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FAP PF07174.11 CAM45492.1 - 4.7 6.6 16.4 5.9 6.2 16.4 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) SPATA3 PF15662.5 CAM45492.1 - 5 7.7 12.5 6.9 7.2 12.5 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family Mitofilin PF09731.9 CAM45492.1 - 9.5 4.9 11.8 11 4.7 11.8 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein FtsJ PF01728.19 CAM45493.2 - 8.2e-55 185.6 0.0 1.3e-54 185.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Spb1_C PF07780.12 CAM45493.2 - 1.4e-30 106.6 17.2 1.4e-30 106.6 17.2 3.2 3 0 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.8 CAM45493.2 - 3.8e-29 101.6 1.6 3.8e-29 101.6 1.6 4.5 4 1 0 4 4 4 1 Domain of unknown function (DUF3381) TrmB PF01978.19 CAM45493.2 - 0.075 12.9 0.2 0.26 11.2 0.2 2.0 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB RabGAP-TBC PF00566.18 CAM45494.2 - 8.9e-28 97.4 0.2 1.3e-15 57.6 0.0 3.4 4 0 0 4 4 4 3 Rab-GTPase-TBC domain TRAM1 PF08390.11 CAM45494.2 - 0.24 11.1 0.1 0.48 10.1 0.1 1.4 1 0 0 1 1 1 0 TRAM1-like protein GMP_PDE_delta PF05351.11 CAM45495.1 - 3.2e-62 209.2 0.0 3.7e-62 209.0 0.0 1.0 1 0 0 1 1 1 1 GMP-PDE, delta subunit ATG16 PF08614.11 CAM45496.2 - 0.0013 19.0 2.8 0.0024 18.1 2.8 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) ubiquitin PF00240.23 CAM45496.2 - 0.054 13.3 0.3 0.33 10.7 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin family ST7 PF04184.12 CAM45496.2 - 0.21 10.0 1.3 0.29 9.6 1.3 1.1 1 0 0 1 1 1 0 ST7 protein FAD-oxidase_C PF02913.19 CAM45497.1 - 2.7e-40 138.6 0.1 4.5e-40 137.9 0.1 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CAM45497.1 - 6.4e-36 123.1 2.9 1.1e-35 122.3 2.2 1.8 2 0 0 2 2 2 1 FAD binding domain Aminotran_4 PF01063.19 CAM45498.1 - 2.5e-30 106.0 0.0 3.2e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Erv26 PF04148.13 CAM45499.2 - 5.1e-18 65.7 15.6 3e-17 63.1 15.6 1.8 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 DUF5090 PF17009.5 CAM45499.2 - 3 7.8 13.0 10 6.0 13.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5090) Ribonuc_red_sm PF00268.21 CAM45500.1 - 4.8e-111 370.7 0.1 6e-111 370.4 0.1 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain NMT PF01233.19 CAM45500.1 - 0.11 12.4 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain OCRE PF17780.1 CAM45502.1 - 5.7e-05 23.1 2.1 0.00012 22.0 2.1 1.5 1 0 0 1 1 1 1 OCRE domain DUF4064 PF13273.6 CAM45502.1 - 0.36 11.1 3.1 1.3 9.3 1.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Noelin-1 PF12308.8 CAM45503.1 - 0.1 12.6 0.1 0.13 12.3 0.1 1.3 1 1 0 1 1 1 0 Neurogenesis glycoprotein RRM_1 PF00076.22 CAM45505.2 - 1.1e-31 108.5 0.0 2.1e-12 46.7 0.0 3.5 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CAM45505.2 - 4.4e-10 39.4 0.1 5.1e-06 26.4 0.0 3.3 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CAM45505.2 - 3.8e-07 29.9 0.0 0.00016 21.5 0.0 2.4 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_7 PF16367.5 CAM45505.2 - 2.6e-05 24.3 0.1 0.03 14.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif zf-CCHC PF00098.23 CAM45505.2 - 0.00071 19.5 0.5 0.0016 18.4 0.5 1.7 1 0 0 1 1 1 1 Zinc knuckle Nucleoporin_FG2 PF15967.5 CAM45505.2 - 0.028 13.0 0.3 0.028 13.0 0.3 1.9 2 1 0 2 2 2 0 Nucleoporin FG repeated region RRM_3 PF08777.11 CAM45505.2 - 0.037 14.1 0.0 3.3 7.8 0.0 2.9 3 0 0 3 3 3 0 RNA binding motif zf-CCHC_3 PF13917.6 CAM45505.2 - 0.047 13.7 2.1 0.1 12.5 2.1 1.5 1 0 0 1 1 1 0 Zinc knuckle PHM7_cyt PF14703.6 CAM45505.2 - 0.07 13.4 0.4 13 6.0 0.0 3.5 2 2 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Lipase_3 PF01764.25 CAM45506.1 - 4.5e-14 52.5 0.0 1.8e-11 44.1 0.0 2.4 2 0 0 2 2 2 2 Lipase (class 3) C1_1 PF00130.22 CAM45506.1 - 0.0005 19.9 2.4 0.0067 16.3 0.8 2.3 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 CAM45506.1 - 0.0077 16.5 1.8 0.0096 16.2 0.3 1.9 2 0 0 2 2 2 1 C1 domain Hydrolase_4 PF12146.8 CAM45506.1 - 0.0096 15.2 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Zf_RING PF16744.5 CAM45506.1 - 0.02 15.0 0.3 0.02 15.0 0.3 1.8 2 0 0 2 2 2 0 KIAA1045 RING finger DUF2974 PF11187.8 CAM45506.1 - 0.2 11.2 0.0 1.3 8.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Motile_Sperm PF00635.26 CAM45507.1 - 3.9e-06 26.7 0.0 1e-05 25.3 0.0 1.8 1 1 0 1 1 1 1 MSP (Major sperm protein) domain PI3_PI4_kinase PF00454.27 CAM45509.1 - 4.9e-20 72.4 0.0 8.7e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF1465 PF07323.12 CAM45509.1 - 0.04 13.7 1.3 0.088 12.6 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) WD40 PF00400.32 CAM45512.2 - 2.8e-13 50.1 0.9 0.0027 18.5 0.2 6.8 7 0 0 7 7 7 3 WD domain, G-beta repeat BORCS6 PF10157.9 CAM45512.2 - 0.0097 16.1 1.7 0.029 14.6 0.1 2.7 2 0 0 2 2 2 1 BLOC-1-related complex sub-unit 6 DUF603 PF04645.12 CAM45512.2 - 0.2 11.4 2.6 0.35 10.6 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF603 NIF PF03031.18 CAM45513.1 - 3.4e-26 91.9 0.0 5.2e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase VKOR PF07884.14 CAM45514.1 - 1.7e-17 63.7 17.1 2.1e-17 63.5 17.1 1.1 1 0 0 1 1 1 1 Vitamin K epoxide reductase family Thioredoxin PF00085.20 CAM45515.2 - 3.1e-06 27.1 0.0 5.4e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 CAM45515.2 - 2.4e-05 23.4 0.2 3e-05 23.1 0.2 1.1 1 0 0 1 1 1 1 Phosducin DSPc PF00782.20 CAM45516.1 - 1.1e-28 99.6 0.0 1.6e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CAM45516.1 - 0.0026 17.4 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Ribosomal_L11_N PF03946.14 CAM45517.1 - 1.8e-15 56.5 0.0 3e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CAM45517.1 - 8.2e-15 55.1 0.0 1.5e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain DUF1451 PF07295.11 CAM45518.2 - 3 7.9 6.2 1 9.4 0.8 2.9 2 0 0 2 2 2 0 Zinc-ribbon containing domain Atg14 PF10186.9 CAM45519.2 - 9.7e-07 28.2 4.0 1.5e-06 27.5 4.0 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 TFIIA PF03153.13 CAM45519.2 - 0.14 12.1 6.0 0.18 11.8 6.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Bap31_Bap29_C PF18035.1 CAM45519.2 - 0.23 11.5 8.8 0.47 10.5 8.3 1.8 1 1 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain EMG1 PF03587.14 CAM45520.1 - 8.6e-39 133.2 0.0 1.1e-38 132.9 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase DUF5372 PF17342.2 CAM45521.2 - 0.38 11.2 2.6 0.51 10.8 0.7 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5372) Herpes_UL25 PF01499.16 CAM45522.1 - 0.46 8.9 4.5 0.85 8.1 4.5 1.4 1 0 0 1 1 1 0 Herpesvirus UL25 family Mcp5_PH PF12814.7 CAM45523.1 - 1.7e-15 57.2 0.5 2.1e-15 56.9 0.5 1.1 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 CAM45523.1 - 0.00012 22.6 0.6 0.00014 22.3 0.6 1.1 1 0 0 1 1 1 1 PH domain PH_2 PF08458.10 CAM45523.1 - 0.011 16.0 1.0 0.013 15.9 0.0 1.5 2 0 0 2 2 2 0 Plant pleckstrin homology-like region ACOX PF01756.19 CAM45524.1 - 4.7e-09 36.1 0.1 1.1e-08 34.9 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA oxidase DUF384 PF04064.13 CAM45524.1 - 0.048 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF384) Spt5-NGN PF03439.13 CAM45525.1 - 2.2e-21 75.6 0.9 7.4e-21 73.8 0.1 2.3 3 0 0 3 3 3 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 CAM45525.1 - 1.8e-06 27.7 5.4 0.075 13.0 0.1 4.2 4 0 0 4 4 4 2 KOW motif HAS-barrel PF09378.10 CAM45525.1 - 0.043 14.0 5.5 0.37 11.0 0.0 3.3 4 0 0 4 4 4 0 HAS barrel domain Hormone_3 PF00159.18 CAM45525.1 - 0.067 13.3 2.1 4.1 7.6 0.3 2.7 2 0 0 2 2 2 0 Pancreatic hormone peptide MORN PF02493.20 CAM45526.1 - 8.1e-20 69.5 15.8 2.8e-06 26.9 0.1 4.6 5 0 0 5 5 5 4 MORN repeat PP2C PF00481.21 CAM45528.1 - 3.6e-75 252.9 0.0 4.5e-75 252.6 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C SCRL PF06876.12 CAM45528.1 - 0.062 13.5 0.1 0.18 12.0 0.1 1.7 1 0 0 1 1 1 0 Plant self-incompatibility response (SCRL) protein YchF-GTPase_C PF06071.13 CAM45529.1 - 2.6e-37 126.9 0.4 6.5e-37 125.6 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 CAM45529.1 - 6.2e-22 77.8 0.0 4.2e-21 75.2 0.0 2.1 1 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CAM45529.1 - 0.00021 20.9 0.0 0.00055 19.5 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B TGS PF02824.21 CAM45529.1 - 0.025 14.6 0.0 0.058 13.5 0.0 1.6 1 0 0 1 1 1 0 TGS domain MeaB PF03308.16 CAM45529.1 - 0.032 13.2 0.0 0.05 12.6 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 CAM45529.1 - 0.036 14.3 0.0 0.91 9.8 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 CAM45529.1 - 0.046 14.3 0.0 0.15 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 CAM45529.1 - 0.076 13.1 0.2 14 5.7 0.1 2.6 2 1 1 3 3 3 0 Dynamin family IATP PF04568.12 CAM45530.1 - 0.13 12.7 1.8 0.11 13.0 0.5 1.6 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Cpn60_TCP1 PF00118.24 CAM45531.1 - 0.03 13.0 0.0 0.044 12.4 0.0 1.1 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family Glyco_hydro_32N PF00251.20 CAM45532.2 - 8.7e-85 284.9 2.0 1.1e-84 284.6 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 CAM45532.2 - 1.9e-20 73.5 0.0 2.8e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_43 PF04616.14 CAM45532.2 - 3.1e-06 26.7 0.5 5e-06 26.0 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 zf_CopZ PF18423.1 CAM45532.2 - 0.057 13.4 0.3 0.15 12.0 0.3 1.7 1 0 0 1 1 1 0 Zinc binding domain Synaptobrevin PF00957.21 CAM45533.1 - 9.3e-25 86.3 0.7 1.5e-24 85.6 0.7 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CAM45533.1 - 3.4e-10 39.8 0.2 5.9e-10 39.0 0.2 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain HHV-5_US34A PF17087.5 CAM45535.1 - 0.14 12.3 2.3 0.36 11.0 1.5 2.1 2 1 0 2 2 2 0 Herpesvirus US34A protein family RPAP3_C PF13877.6 CAM45537.2 - 6.1e-15 55.5 0.0 1.1e-14 54.7 0.0 1.5 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_2 PF07719.17 CAM45537.2 - 2.1e-13 49.3 2.5 9.3e-05 22.3 0.8 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CAM45537.2 - 9.1e-12 44.3 2.3 6.3e-05 22.6 0.3 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CAM45537.2 - 6.6e-10 38.4 1.7 0.0004 20.4 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 CAM45537.2 - 2.4e-07 30.3 2.3 0.00058 19.5 0.0 3.6 3 2 2 5 5 5 2 TPR repeat TPR_19 PF14559.6 CAM45537.2 - 6.2e-05 23.4 2.1 0.095 13.2 0.1 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 CAM45537.2 - 0.00013 22.1 0.2 0.81 10.2 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 CAM45537.2 - 0.00017 21.7 21.0 0.00019 21.5 0.9 4.8 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 CAM45537.2 - 0.00021 21.8 2.8 0.0025 18.5 1.7 4.5 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 CAM45537.2 - 0.00065 20.3 1.2 0.00065 20.3 1.2 5.2 5 1 0 6 6 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 CAM45537.2 - 0.0028 17.9 5.3 0.053 13.8 3.9 3.1 2 1 0 2 2 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CAM45537.2 - 0.011 15.9 0.9 0.031 14.5 0.9 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 MRP-L28 PF09812.9 CAM45537.2 - 0.021 15.0 0.1 0.021 15.0 0.1 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 TPR_7 PF13176.6 CAM45537.2 - 0.082 13.0 5.5 23 5.3 0.3 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CAM45537.2 - 0.096 13.4 12.0 0.19 12.4 0.8 4.0 4 0 0 4 4 2 0 Tetratricopeptide repeat Rrn6 PF10214.9 CAM45537.2 - 2.7 6.4 14.7 4 5.8 14.7 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DnaJ_C PF01556.18 CAM45538.1 - 3.8e-32 111.4 0.0 5.1e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CAM45538.1 - 2.1e-28 98.2 1.0 1.3e-27 95.7 0.3 2.1 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CAM45538.1 - 2.4e-14 53.4 16.0 4e-14 52.7 16.0 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CAM45538.1 - 0.12 12.4 14.6 0.34 10.9 3.3 2.6 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 CAM45538.1 - 1 9.4 10.8 1.2 9.2 1.0 2.6 1 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 CAM45538.1 - 2.9 8.0 12.5 1.9e+02 2.2 12.5 2.6 1 1 0 1 1 1 0 Double zinc ribbon RseC_MucC PF04246.12 CAM45538.1 - 6.6 6.7 9.1 0.49 10.4 1.2 2.2 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Aldo_ket_red PF00248.21 CAM45539.1 - 7e-34 117.4 0.0 1.4e-33 116.4 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family TBPIP PF07106.13 CAM45540.1 - 4.1e-08 33.0 0.0 6e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain Cep57_MT_bd PF06657.13 CAM45540.1 - 0.043 14.3 0.1 0.15 12.5 0.0 1.9 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 adh_short_C2 PF13561.6 CAM45542.1 - 8.7e-42 143.3 0.1 1e-41 143.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CAM45542.1 - 1e-32 113.2 0.0 1.4e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CAM45542.1 - 2.2e-09 37.5 0.3 4.9e-09 36.4 0.3 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CAM45542.1 - 0.024 14.1 0.0 0.069 12.6 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pkinase PF00069.25 CAM45544.1 - 5.2e-50 170.3 0.0 1.2e-49 169.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM45544.1 - 4.2e-23 81.9 0.0 7.7e-23 81.1 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM45544.1 - 0.0011 18.4 0.0 0.53 9.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 CAM45544.1 - 0.0032 16.8 0.0 0.0043 16.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CAM45544.1 - 0.0066 16.4 0.6 0.24 11.3 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family DHDPS PF00701.22 CAM45544.1 - 0.0068 15.2 0.0 0.0098 14.6 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Pkinase PF00069.25 CAM45545.1 - 2.1e-65 220.7 0.0 3.6e-65 220.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM45545.1 - 7.9e-30 104.0 0.0 1.2e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM45545.1 - 0.00019 20.8 0.0 0.0043 16.4 0.0 2.3 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 CAM45545.1 - 0.016 14.6 0.5 0.22 10.8 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Prp19 PF08606.11 CAM45546.2 - 1.7e-24 85.5 0.2 4.7e-24 84.2 0.2 1.7 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 CAM45546.2 - 1.4e-08 35.2 11.4 0.25 12.3 0.0 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat PALB2_WD40 PF16756.5 CAM45546.2 - 0.011 14.6 0.1 0.18 10.7 0.0 2.2 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 CAM45546.2 - 0.017 13.5 0.0 3.1 6.0 0.0 2.2 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz U-box PF04564.15 CAM45546.2 - 0.023 14.9 0.0 0.048 13.8 0.0 1.5 1 0 0 1 1 1 0 U-box domain zf-Nse PF11789.8 CAM45546.2 - 0.039 13.8 0.1 0.078 12.8 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit ANAPC4_WD40 PF12894.7 CAM45546.2 - 0.046 14.0 0.1 10 6.5 0.0 4.0 1 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain TTL PF03133.15 CAM45547.1 - 1.7e-47 162.0 0.0 2.4e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CAM45547.1 - 0.0001 21.7 0.0 0.19 10.9 0.0 2.8 1 1 1 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CAM45547.1 - 0.022 14.0 0.0 0.053 12.8 0.0 1.5 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Dala_Dala_lig_C PF07478.13 CAM45547.1 - 0.054 13.0 0.0 0.087 12.3 0.0 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus AAA_6 PF12774.7 CAM45548.1 - 2.3e-155 516.5 0.0 3.8e-153 509.2 0.0 3.1 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CAM45548.1 - 2.1e-114 382.8 7.1 6.1e-114 381.2 7.1 1.9 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 CAM45548.1 - 3.2e-109 364.9 0.0 1e-108 363.2 0.0 1.9 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 CAM45548.1 - 4.7e-91 304.7 0.0 1.4e-90 303.2 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 CAM45548.1 - 4.4e-76 254.4 0.0 4.3e-73 244.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_9 PF12781.7 CAM45548.1 - 5.3e-73 244.8 4.1 1.2e-72 243.6 4.1 1.7 1 0 0 1 1 1 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 CAM45548.1 - 2.7e-59 199.7 0.0 6.6e-59 198.4 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CAM45548.1 - 8.7e-38 129.1 0.0 1e-35 122.4 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 CAM45548.1 - 3.8e-27 95.2 8.3 3.8e-27 95.2 8.3 2.1 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 CAM45548.1 - 2.7e-20 72.8 0.0 7.4e-20 71.3 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CAM45548.1 - 1.5e-18 67.2 0.0 7.4e-05 22.8 0.0 6.0 5 2 1 6 6 6 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 CAM45548.1 - 1e-13 51.3 0.0 3.4e-13 49.6 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 CAM45548.1 - 4.7e-09 36.8 2.5 0.003 18.0 0.0 4.2 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CAM45548.1 - 3.3e-07 30.7 5.2 0.023 14.9 0.0 6.4 7 0 0 7 7 6 2 AAA domain AAA_30 PF13604.6 CAM45548.1 - 1.8e-05 24.5 2.9 0.072 12.8 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 CAM45548.1 - 9.2e-05 23.0 0.0 0.0074 16.8 0.0 3.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CAM45548.1 - 0.00024 21.5 14.2 0.13 12.6 0.0 7.4 7 0 0 7 7 6 1 AAA ATPase domain RNA_helicase PF00910.22 CAM45548.1 - 0.0034 17.7 0.1 3.2 8.2 0.0 3.2 2 0 0 2 2 2 1 RNA helicase T2SSE PF00437.20 CAM45548.1 - 0.0072 15.4 0.8 0.06 12.4 0.0 3.0 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_33 PF13671.6 CAM45548.1 - 0.012 15.8 0.1 3.7 7.7 0.0 3.9 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.13 CAM45548.1 - 0.013 14.7 0.0 0.044 12.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF853 PF05872.12 CAM45548.1 - 0.018 13.7 0.9 1 7.8 0.0 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) TsaE PF02367.17 CAM45548.1 - 0.019 15.0 1.6 1.5 8.8 0.0 3.6 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MobB PF03205.14 CAM45548.1 - 0.039 13.8 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.17 CAM45548.1 - 0.077 12.7 0.0 0.78 9.4 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein RBD-FIP PF09457.10 CAM45548.1 - 0.079 12.9 2.9 0.38 10.7 0.0 3.4 3 0 0 3 3 2 0 FIP domain CbiA PF01656.23 CAM45548.1 - 0.089 12.8 0.0 2 8.5 0.0 2.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain ResIII PF04851.15 CAM45548.1 - 0.27 11.2 1.1 0.91 9.5 0.0 2.5 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit TPR_12 PF13424.6 CAM45548.1 - 0.28 11.5 5.3 2.4 8.5 0.3 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat COG2 PF06148.11 CAM45548.1 - 4.1 7.5 7.6 35 4.5 0.5 3.8 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 CAM45548.1 - 4.2 7.4 8.6 3.5 7.7 0.3 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) AAA_28 PF13521.6 CAM45548.1 - 9.1 6.5 9.4 1.7 8.9 0.0 4.4 4 0 0 4 4 3 0 AAA domain HTH_9 PF08221.11 CAM45549.2 - 0.00026 21.0 0.9 0.081 13.0 0.0 3.4 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain KxDL PF10241.9 CAM45550.1 - 0.19 12.0 5.7 0.52 10.6 3.7 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein CREPT PF16566.5 CAM45550.1 - 0.21 11.8 8.0 2.5 8.3 1.4 2.6 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF2316 PF10078.9 CAM45551.1 - 0.44 10.8 6.5 4 7.8 0.3 3.8 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) AAA_2 PF07724.14 CAM45552.1 - 1e-52 178.7 0.0 4.6e-50 170.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CAM45552.1 - 6.7e-32 109.5 2.5 6.7e-32 109.5 2.5 2.4 2 0 0 2 2 2 1 AAA lid domain AAA PF00004.29 CAM45552.1 - 1.6e-23 83.6 0.1 9.2e-14 52.0 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CAM45552.1 - 4.2e-22 78.0 0.2 1.4e-21 76.3 0.2 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 CAM45552.1 - 3.2e-18 66.1 0.4 3.3e-10 40.1 0.0 4.2 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CAM45552.1 - 4.6e-11 43.4 4.0 7.1e-05 23.2 0.3 4.3 3 2 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 CAM45552.1 - 2.5e-08 34.3 5.8 0.0037 17.5 0.0 5.3 4 3 1 5 5 4 2 AAA domain AAA_7 PF12775.7 CAM45552.1 - 9.6e-07 28.5 0.0 0.0059 16.1 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region Mg_chelatase PF01078.21 CAM45552.1 - 4e-05 23.1 0.0 0.35 10.2 0.0 3.4 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CAM45552.1 - 4.8e-05 23.2 0.1 0.071 12.8 0.0 2.9 3 0 0 3 3 3 1 IstB-like ATP binding protein RNA_helicase PF00910.22 CAM45552.1 - 5.4e-05 23.5 0.0 0.84 10.0 0.0 3.1 3 0 0 3 3 2 2 RNA helicase AAA_18 PF13238.6 CAM45552.1 - 5.4e-05 23.7 1.1 0.084 13.4 0.0 3.3 3 1 0 3 3 2 1 AAA domain NACHT PF05729.12 CAM45552.1 - 0.00036 20.5 0.1 0.052 13.5 0.0 3.4 3 0 0 3 3 3 1 NACHT domain AAA_14 PF13173.6 CAM45552.1 - 0.00039 20.5 0.0 0.42 10.6 0.0 3.1 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 CAM45552.1 - 0.00042 20.1 0.0 0.28 10.9 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain RuvB_N PF05496.12 CAM45552.1 - 0.00052 19.8 0.1 2 8.2 0.0 3.4 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 CAM45552.1 - 0.0013 18.6 0.0 1.1 9.1 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 CAM45552.1 - 0.0017 18.5 0.0 1.4 9.2 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 CAM45552.1 - 0.0026 18.1 0.0 0.34 11.2 0.1 3.2 3 1 0 3 3 3 1 AAA domain DNA_pol3_delta2 PF13177.6 CAM45552.1 - 0.0028 17.5 1.8 4.3 7.1 0.0 3.6 3 1 0 3 3 3 1 DNA polymerase III, delta subunit ResIII PF04851.15 CAM45552.1 - 0.0031 17.5 0.0 2.1 8.3 0.0 3.7 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 CAM45552.1 - 0.0039 17.1 5.2 5.1 6.9 0.0 4.5 3 2 2 6 6 5 0 ATPase domain predominantly from Archaea DUF815 PF05673.13 CAM45552.1 - 0.0049 16.1 0.2 0.15 11.2 0.0 3.1 3 1 0 3 3 3 1 Protein of unknown function (DUF815) TsaE PF02367.17 CAM45552.1 - 0.007 16.4 0.0 2.9 7.9 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 CAM45552.1 - 0.0071 16.0 0.0 1.4 8.5 0.0 3.2 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 CAM45552.1 - 0.0081 16.1 0.0 3.4 7.5 0.0 3.0 2 1 0 2 2 2 1 RsgA GTPase Torsin PF06309.11 CAM45552.1 - 0.012 15.7 0.0 0.041 14.0 0.0 1.8 2 0 0 2 2 1 0 Torsin AAA_33 PF13671.6 CAM45552.1 - 0.012 15.7 0.0 8.5 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CAM45552.1 - 0.013 15.3 0.0 7.6 6.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CAM45552.1 - 0.013 15.8 0.2 2.9 8.1 0.0 3.3 4 0 0 4 4 2 0 AAA domain Ribosomal_S7 PF00177.21 CAM45552.1 - 0.024 14.3 0.0 0.076 12.7 0.0 1.8 1 0 0 1 1 1 0 Ribosomal protein S7p/S5e AAA_25 PF13481.6 CAM45552.1 - 0.026 14.1 0.1 2.9 7.4 0.0 3.5 4 0 0 4 4 4 0 AAA domain NTPase_1 PF03266.15 CAM45552.1 - 0.03 14.2 0.0 5.3 6.9 0.0 2.9 2 0 0 2 2 2 0 NTPase AAA_29 PF13555.6 CAM45552.1 - 0.039 13.7 0.0 10 5.9 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_6 PF12774.7 CAM45552.1 - 0.047 12.7 0.1 0.23 10.4 0.0 2.2 3 0 0 3 3 2 0 Hydrolytic ATP binding site of dynein motor region ABC_tran PF00005.27 CAM45552.1 - 0.057 13.9 2.0 10 6.7 0.0 3.3 3 1 0 3 3 3 0 ABC transporter AAA_30 PF13604.6 CAM45552.1 - 0.064 13.0 0.1 7.7 6.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 CAM45552.1 - 0.12 12.2 0.0 5 6.8 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.6 CAM45552.1 - 0.53 10.7 5.1 10 6.6 0.0 4.1 4 1 1 5 5 4 0 AAA domain WSD PF15613.6 CAM45552.1 - 0.66 10.5 3.1 1.5 9.3 3.1 1.6 1 0 0 1 1 1 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif AAA_23 PF13476.6 CAM45552.1 - 9.6 6.7 14.1 19 5.7 0.0 3.2 2 1 0 2 2 1 0 AAA domain Peptidase_M3 PF01432.20 CAM45553.2 - 4.4e-135 451.5 0.1 5.6e-135 451.1 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M3 CdhD PF03599.16 CAM45553.2 - 0.051 12.3 0.8 0.15 10.8 0.2 1.9 2 0 0 2 2 2 0 CO dehydrogenase/acetyl-CoA synthase delta subunit Peptidase_M50B PF13398.6 CAM45553.2 - 0.14 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Peptidase_M3 PF01432.20 CAM45555.1 - 6.1e-127 424.6 0.0 7.3e-127 424.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 CAM45555.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like MSSP PF03940.13 CAM45556.1 - 0.2 11.3 12.5 1.6 8.4 2.1 2.5 2 0 0 2 2 2 0 Male specific sperm protein HipA_C PF07804.12 CAM45556.1 - 0.27 10.9 0.6 99 2.5 0.0 2.9 3 0 0 3 3 3 0 HipA-like C-terminal domain Form-deh_trans PF09163.11 CAM45556.1 - 3.9 7.3 6.7 4.4e+02 0.8 0.0 5.3 6 0 0 6 6 6 0 Formate dehydrogenase N, transmembrane Amidohydro_2 PF04909.14 CAM45558.1 - 0.0001 22.2 1.2 2.4 7.8 0.1 3.4 2 1 0 3 3 3 3 Amidohydrolase Pkinase PF00069.25 CAM45563.2 - 5.4e-37 127.6 0.0 7.5e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM45563.2 - 9.5e-16 57.8 0.0 1.5e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 CAM45564.1 - 1.6e-10 41.4 5.1 0.19 12.6 0.4 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 CAM45564.1 - 0.026 13.2 0.0 0.12 10.9 0.0 2.0 1 1 0 1 1 1 0 Nucleoporin Nup120/160 PQQ PF01011.21 CAM45564.1 - 0.12 12.3 0.4 0.92 9.5 0.1 2.4 2 0 0 2 2 2 0 PQQ enzyme repeat Prenyltransf PF01255.19 CAM45565.1 - 1.6e-56 191.3 0.2 1.8e-52 178.1 0.0 2.3 2 0 0 2 2 2 2 Putative undecaprenyl diphosphate synthase CLZ PF16526.5 CAM45566.1 - 0.054 13.8 1.8 0.16 12.3 0.9 2.0 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF3086 PF11285.8 CAM45566.1 - 0.057 12.5 0.3 0.074 12.1 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) SKA2 PF16740.5 CAM45566.1 - 0.068 13.0 0.3 0.97 9.2 0.0 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 ZapB PF06005.12 CAM45566.1 - 0.094 13.2 0.7 0.17 12.3 0.7 1.5 1 1 0 1 1 1 0 Cell division protein ZapB Reovirus_cap PF00979.17 CAM45567.1 - 0.11 11.7 1.7 0.17 11.0 1.7 1.2 1 0 0 1 1 1 0 Reovirus outer capsid protein, Sigma 3 RNase_HII PF01351.18 CAM45568.1 - 1.9e-15 57.2 0.1 6.7e-13 48.9 0.1 2.3 1 1 0 1 1 1 1 Ribonuclease HII DNA_pol_A PF00476.20 CAM45570.1 - 1.6e-34 119.6 0.0 4.7e-34 118.0 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase family A RNase_T PF00929.24 CAM45570.1 - 1.2e-15 58.5 0.0 6.4e-15 56.1 0.0 2.4 2 1 0 2 2 2 1 Exonuclease Pro_dh PF01619.18 CAM45570.1 - 0.01 15.4 0.0 0.026 14.0 0.0 1.6 1 0 0 1 1 1 0 Proline dehydrogenase RNase_H_2 PF13482.6 CAM45570.1 - 0.013 15.5 0.0 0.043 13.8 0.0 1.9 2 0 0 2 2 2 0 RNase_H superfamily Peptidase_M32 PF02074.15 CAM45571.1 - 1.5e-154 515.4 0.0 1.7e-154 515.2 0.0 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase AMA-1 PF02430.15 CAM45572.2 - 0.02 13.9 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 Apical membrane antigen 1 DUF5347 PF17282.2 CAM45572.2 - 0.093 13.0 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5347) SURF1 PF02104.15 CAM45573.1 - 2.7e-30 105.9 0.0 4.7e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 SURF1 family DUF1471 PF07338.13 CAM45573.1 - 0.062 13.3 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) Troponin PF00992.20 CAM45574.1 - 0.0033 17.7 4.4 0.0046 17.3 4.4 1.3 1 0 0 1 1 1 1 Troponin Atg14 PF10186.9 CAM45574.1 - 0.004 16.3 6.1 0.0049 16.0 6.1 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_MLP1_2 PF07926.12 CAM45574.1 - 0.017 15.2 12.8 0.42 10.7 3.4 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Jnk-SapK_ap_N PF09744.9 CAM45574.1 - 0.022 15.0 9.0 0.028 14.6 9.0 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 CCDC92 PF14916.6 CAM45574.1 - 0.037 13.8 4.8 0.17 11.7 0.1 2.5 2 1 0 2 2 2 0 Coiled-coil domain of unknown function SDA1 PF05285.12 CAM45574.1 - 0.05 13.0 4.8 0.06 12.8 4.8 1.1 1 0 0 1 1 1 0 SDA1 Exc PF07825.11 CAM45574.1 - 0.082 12.9 0.1 0.42 10.6 0.0 2.0 1 1 1 2 2 2 0 Excisionase-like protein ADIP PF11559.8 CAM45574.1 - 0.087 12.9 8.2 0.14 12.3 8.2 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TMPIT PF07851.13 CAM45574.1 - 0.13 11.5 3.3 0.15 11.3 3.3 1.0 1 0 0 1 1 1 0 TMPIT-like protein Herpes_UL6 PF01763.16 CAM45574.1 - 0.16 10.5 2.1 0.17 10.3 2.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like ANAPC_CDC26 PF10471.9 CAM45574.1 - 0.72 10.7 10.2 0.37 11.6 6.6 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 YabA PF06156.13 CAM45574.1 - 2.9 8.6 7.2 19 5.9 7.4 2.0 1 1 0 1 1 1 0 Initiation control protein YabA APG6_N PF17675.1 CAM45574.1 - 3.4 8.2 16.7 14 6.2 12.1 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Kinesin PF00225.23 CAM45575.2 - 1.8e-87 293.4 0.1 2.4e-87 293.0 0.1 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CAM45575.2 - 2.5e-15 56.7 0.0 5.1e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding zf-TRAF PF02176.18 CAM45575.2 - 6.9e-15 55.5 43.5 9.2e-07 29.5 4.6 5.3 4 1 2 6 6 6 4 TRAF-type zinc finger AAA_22 PF13401.6 CAM45575.2 - 0.0098 16.2 0.3 0.13 12.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain zf-TRAF_2 PF15965.5 CAM45575.2 - 0.064 13.7 0.0 0.064 13.7 0.0 4.6 3 1 2 5 5 5 0 TRAF-like zinc-finger PRP21_like_P PF12230.8 CAM45575.2 - 0.23 11.3 3.8 14 5.4 0.4 3.2 1 1 2 3 3 3 0 Pre-mRNA splicing factor PRP21 like protein zf-Di19 PF05605.12 CAM45575.2 - 0.72 10.2 19.1 7 7.0 2.0 4.3 3 2 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding PHD_4 PF16866.5 CAM45575.2 - 3.8 7.7 21.1 2.6 8.2 6.2 3.4 1 1 2 3 3 3 0 PHD-finger zf-U11-48K PF05253.12 CAM45575.2 - 5.8 7.0 10.9 21 5.1 0.0 5.4 6 0 0 6 6 6 0 U11-48K-like CHHC zinc finger PhyH PF05721.13 CAM45577.1 - 0.068 13.4 0.0 4.9 7.3 0.0 2.7 1 1 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) cNMP_binding PF00027.29 CAM45578.1 - 3.1e-31 107.3 0.4 1.1e-17 63.9 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain DUF333 PF03891.15 CAM45578.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF333) MOZ_SAS PF01853.18 CAM45579.1 - 4.4e-21 75.3 0.0 8e-12 45.2 0.0 2.3 2 0 0 2 2 2 2 MOZ/SAS family zf-MYST PF17772.1 CAM45579.1 - 0.0013 18.3 2.5 0.0013 18.3 2.5 1.9 2 0 0 2 2 2 1 MYST family zinc finger domain TPR_12 PF13424.6 CAM45580.1 - 2.6e-11 43.6 14.8 2.4e-07 30.9 0.2 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 CAM45580.1 - 1e-06 28.4 4.1 0.5 10.6 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 CAM45580.1 - 0.012 16.2 3.6 10 7.0 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 CAM45580.1 - 0.018 15.2 0.6 90 3.7 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CAM45580.1 - 0.051 13.4 0.3 8 6.5 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 CAM45580.1 - 0.14 12.1 16.1 5.2 7.1 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 CAM45580.1 - 2 9.2 10.0 3.4 8.4 0.0 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat Tubulin PF00091.25 CAM45582.2 - 7.3e-65 218.9 0.0 9.8e-65 218.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CAM45582.2 - 4e-50 169.2 0.0 6.7e-50 168.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CAM45582.2 - 0.0073 16.0 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 CAM45583.2 - 7.3e-65 218.9 0.0 9.8e-65 218.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CAM45583.2 - 4e-50 169.2 0.0 6.7e-50 168.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CAM45583.2 - 0.0073 16.0 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 CAM45584.2 - 1.5e-19 70.9 0.0 2.1e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain AMP-binding PF00501.28 CAM45587.1 - 8.9e-62 209.0 0.2 1.2e-61 208.6 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CAM45587.1 - 0.0017 19.3 0.1 0.0096 16.9 0.1 2.4 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain FeoA PF04023.14 CAM45587.1 - 0.036 14.3 0.0 0.13 12.6 0.0 1.9 1 0 0 1 1 1 0 FeoA domain Radial_spoke PF04712.12 CAM45588.1 - 1e-118 397.5 15.5 7e-87 292.4 5.1 2.7 1 1 1 2 2 2 2 Radial spokehead-like protein eIF-3c_N PF05470.12 CAM45588.1 - 5.6 5.1 5.8 11 4.2 5.8 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Pkinase PF00069.25 CAM45589.1 - 6.8e-80 268.2 0.0 1.2e-79 267.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAM45589.1 - 2.2e-45 155.0 0.0 4.2e-45 154.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.6 CAM45589.1 - 6.5e-09 36.1 5.3 0.00029 21.3 0.2 5.1 4 1 1 5 5 5 2 HEAT-like repeat Arm PF00514.23 CAM45589.1 - 4.4e-08 32.9 6.9 0.0018 18.3 0.1 6.5 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Kinase-like PF14531.6 CAM45589.1 - 8.5e-06 25.3 0.0 0.00013 21.4 0.0 2.1 1 1 1 2 2 2 1 Kinase-like HEAT_2 PF13646.6 CAM45589.1 - 9.1e-06 26.0 0.1 0.00016 22.0 0.2 3.0 1 1 1 2 2 2 2 HEAT repeats Pkinase_fungal PF17667.1 CAM45589.1 - 8e-05 21.6 0.0 0.00018 20.4 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase HEAT PF02985.22 CAM45589.1 - 0.00011 22.2 3.1 2.8 8.4 0.0 5.5 4 0 0 4 4 4 1 HEAT repeat RIO1 PF01163.22 CAM45589.1 - 0.00021 20.9 1.1 0.0036 16.9 0.1 2.3 1 1 0 2 2 2 1 RIO1 family FTA2 PF13095.6 CAM45589.1 - 0.0022 17.7 1.4 0.34 10.5 0.1 2.4 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 CAM45589.1 - 0.0047 15.9 0.1 0.0093 14.9 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 CAM45589.1 - 0.0051 16.3 0.1 0.011 15.2 0.1 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.23 CAM45589.1 - 0.0074 16.2 0.0 0.024 14.5 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CAM45589.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Urb2 PF10441.9 CAM45589.1 - 0.014 15.3 0.1 0.081 12.8 0.0 2.3 2 0 0 2 2 2 0 Urb2/Npa2 family Seadorna_VP7 PF07387.11 CAM45589.1 - 0.014 14.5 0.0 0.033 13.3 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 ABC1 PF03109.16 CAM45589.1 - 0.032 14.4 0.1 0.25 11.5 0.0 2.2 1 1 1 2 2 2 0 ABC1 family WAPL PF07814.13 CAM45589.1 - 0.049 12.4 0.7 0.25 10.1 0.2 2.3 2 0 0 2 2 2 0 Wings apart-like protein regulation of heterochromatin DUF3361 PF11841.8 CAM45589.1 - 0.1 12.5 0.0 18 5.2 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) PIP49_C PF12260.8 CAM45589.1 - 0.12 12.0 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Alba PF01918.21 CAM45590.1 - 4.2e-15 55.3 0.3 7.1e-15 54.6 0.3 1.3 1 0 0 1 1 1 1 Alba Rpp20 PF12328.8 CAM45590.1 - 0.0013 18.7 0.8 0.0016 18.4 0.8 1.2 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P AlphaC_N PF08829.10 CAM45590.1 - 0.044 13.8 0.0 0.06 13.4 0.0 1.3 1 0 0 1 1 1 0 Alpha C protein N terminal Phage_ABA_S PF18066.1 CAM45590.1 - 0.071 13.8 0.0 0.12 13.1 0.0 1.6 1 1 0 1 1 1 0 Phage ABA sandwich domain C2 PF00168.30 CAM45591.1 - 0.0034 17.6 0.1 0.0097 16.2 0.0 1.8 2 0 0 2 2 2 1 C2 domain Maf PF02545.14 CAM45591.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Maf-like protein CENP-F_leu_zip PF10473.9 CAM45593.1 - 5.8e-08 32.9 56.3 0.0057 16.7 14.5 6.3 3 2 3 6 6 6 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.8 CAM45593.1 - 4.4e-05 23.7 2.4 4.4e-05 23.7 2.4 5.8 3 1 2 6 6 6 2 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 CAM45593.1 - 0.00074 18.5 16.8 0.00074 18.5 16.8 3.2 2 1 2 4 4 4 1 Spc7 kinetochore protein DUF2353 PF09789.9 CAM45593.1 - 0.0041 16.5 46.0 0.014 14.8 20.7 3.9 2 1 2 4 4 4 3 Uncharacterized coiled-coil protein (DUF2353) Filament PF00038.21 CAM45593.1 - 0.019 14.5 56.4 0.075 12.6 6.9 4.4 2 1 2 4 4 4 0 Intermediate filament protein Fez1 PF06818.15 CAM45593.1 - 0.035 14.5 54.0 0.67 10.4 23.3 4.1 1 1 2 3 3 3 0 Fez1 Uso1_p115_C PF04871.13 CAM45593.1 - 0.043 14.2 0.9 0.043 14.2 0.9 5.5 2 1 4 6 6 6 0 Uso1 / p115 like vesicle tethering protein, C terminal region GAS PF13851.6 CAM45593.1 - 0.06 12.7 57.9 0.58 9.5 1.4 4.8 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding BCL_N PF04714.13 CAM45593.1 - 0.17 12.0 7.8 0.73 9.9 0.0 3.5 3 0 0 3 3 3 0 BCL7, N-terminal conserver region DUF4407 PF14362.6 CAM45593.1 - 0.65 9.3 46.9 0.021 14.2 14.9 3.6 2 1 2 4 4 4 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 CAM45593.1 - 0.68 10.4 21.6 3.6 8.1 0.3 5.6 4 1 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 CAM45593.1 - 0.71 10.1 37.2 0.12 12.5 3.9 4.8 2 1 4 6 6 6 0 Fibrinogen alpha/beta chain family IFP_35_N PF07334.13 CAM45593.1 - 1 9.5 10.8 7 6.8 1.3 4.8 4 0 0 4 4 4 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus BST2 PF16716.5 CAM45593.1 - 1.8 9.2 52.8 0.1 13.2 3.2 6.8 2 1 3 7 7 7 0 Bone marrow stromal antigen 2 THP2 PF09432.10 CAM45593.1 - 1.9 8.5 22.9 0.91 9.6 1.9 3.4 3 0 0 3 3 3 0 Tho complex subunit THP2 WD40_alt PF14077.6 CAM45593.1 - 7.5 6.5 10.1 1.8 8.5 1.1 4.3 4 1 1 5 5 5 0 Alternative WD40 repeat motif LPP PF04728.13 CAM45593.1 - 8.9 6.8 20.3 2.4 8.6 2.5 6.1 6 1 0 6 6 6 0 Lipoprotein leucine-zipper Leu_zip PF15294.6 CAM45593.1 - 8.9 5.7 40.9 0.14 11.7 3.7 3.7 2 1 2 4 4 4 0 Leucine zipper His_Phos_1 PF00300.22 CAM45594.1 - 1.6e-08 34.5 0.0 1.2e-05 25.1 0.0 2.9 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Sec63 PF02889.16 CAM45595.1 - 1.2e-142 473.6 4.4 1.3e-80 270.2 1.4 2.5 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 CAM45595.1 - 5.3e-53 179.4 0.0 6.2e-28 97.7 0.1 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 CAM45595.1 - 5.7e-29 101.3 0.0 1.1e-16 61.3 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CAM45595.1 - 6.7e-16 58.6 0.0 4.4e-07 30.2 0.0 4.0 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_30 PF13604.6 CAM45595.1 - 4.2e-10 39.7 0.0 8.9e-05 22.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CAM45595.1 - 9e-07 29.3 2.9 0.00071 19.9 0.1 3.2 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 CAM45595.1 - 5.3e-06 26.8 1.1 0.0022 18.3 0.0 3.6 3 2 0 3 3 2 1 AAA domain T2SSE PF00437.20 CAM45595.1 - 0.00026 20.1 0.0 0.68 8.9 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein SWI2_SNF2 PF18766.1 CAM45595.1 - 0.00032 20.4 0.1 0.043 13.5 0.1 2.3 2 0 0 2 2 2 1 SWI2/SNF2 ATPase PhoH PF02562.16 CAM45595.1 - 0.0008 18.9 0.1 0.13 11.7 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein DUF2075 PF09848.9 CAM45595.1 - 0.0011 18.3 0.0 0.003 16.8 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SpuA_C PF18033.1 CAM45595.1 - 0.0041 17.1 0.3 0.92 9.6 0.1 3.1 2 0 0 2 2 2 1 SpuA C-terminal AAA_7 PF12775.7 CAM45595.1 - 0.01 15.3 0.2 1.4 8.4 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region TniB PF05621.11 CAM45595.1 - 0.032 13.7 0.1 1.8 8.0 0.0 3.1 3 0 0 3 3 3 0 Bacterial TniB protein UvrD-helicase PF00580.21 CAM45595.1 - 0.05 13.1 0.6 2.6 7.5 0.0 2.6 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain AAA PF00004.29 CAM45595.1 - 0.06 13.8 1.1 5 7.6 0.2 3.8 3 2 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 CAM45595.1 - 0.061 13.0 0.0 17 5.1 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein Ccdc124 PF06244.12 CAM45597.1 - 4.9e-24 85.3 21.4 1.9e-22 80.2 21.4 2.3 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 DUF3435 PF11917.8 CAM45597.1 - 0.029 13.3 12.4 0.042 12.8 12.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) HMG_box PF00505.19 CAM45597.1 - 0.048 14.1 0.5 0.048 14.1 0.5 3.2 2 1 1 3 3 3 0 HMG (high mobility group) box COG2 PF06148.11 CAM45597.1 - 10 6.2 12.0 7.7 6.6 8.5 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 PDZ_assoc PF10600.9 CAM45598.1 - 0.41 11.5 6.2 5.6 7.9 4.8 3.0 2 0 0 2 2 2 0 PDZ-associated domain of NMDA receptors DUF179 PF02622.15 CAM45600.1 - 2.9e-19 69.6 0.0 5.6e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 Ribosomal_L18 PF17135.4 CAM45601.1 - 2.1e-74 249.0 2.9 2.5e-74 248.7 2.9 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 CAM45601.1 - 0.00026 21.7 0.1 0.00082 20.1 0.1 1.9 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L7Ae PF01248.26 CAM45602.1 - 4.4e-22 77.6 1.0 5.7e-22 77.3 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ZapB PF06005.12 CAM45603.1 - 0.019 15.4 0.5 0.056 13.9 0.5 1.8 1 0 0 1 1 1 0 Cell division protein ZapB Atg14 PF10186.9 CAM45603.1 - 0.069 12.2 5.3 2.1 7.4 1.2 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 MCU PF04678.13 CAM45605.1 - 4.1e-11 43.3 0.1 5.4e-11 42.9 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial calcium uniporter DUF1192 PF06698.11 CAM45605.1 - 0.012 15.7 0.1 0.045 13.8 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Acetyltransf_10 PF13673.7 CAM45606.1 - 8.6e-07 28.9 0.0 1.6e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CAM45606.1 - 0.0018 18.5 0.0 0.0035 17.5 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CAM45606.1 - 0.0043 17.5 0.0 0.0084 16.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DBD_Tnp_Mut PF03108.15 CAM45606.1 - 0.094 12.7 0.4 0.31 11.1 0.0 2.0 2 0 0 2 2 2 0 MuDR family transposase ABC_tran_CTD PF16326.5 CAM45607.2 - 0.029 14.6 1.1 0.029 14.6 1.1 1.9 2 0 0 2 2 2 0 ABC transporter C-terminal domain UPF0242 PF06785.11 CAM45607.2 - 0.76 9.9 3.7 1.2 9.2 3.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4061 PF13270.6 CAM45608.1 - 0.02 15.2 0.0 0.048 14.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) Cse1 PF08506.10 CAM45609.2 - 0.0067 15.3 0.0 0.016 14.0 0.0 1.6 1 0 0 1 1 1 1 Cse1 Xpo1 PF08389.12 CAM45609.2 - 0.12 12.4 0.1 1.5 8.9 0.0 2.8 2 0 0 2 2 2 0 Exportin 1-like protein HEAT_EZ PF13513.6 CAM45609.2 - 0.57 10.8 6.7 0.16 12.5 0.3 3.5 3 0 0 3 3 3 0 HEAT-like repeat HEAT PF02985.22 CAM45609.2 - 2.3 8.7 7.4 0.26 11.6 0.2 3.6 3 0 0 3 3 3 0 HEAT repeat DHHC PF01529.20 CAM45610.1 - 4.2e-26 91.7 12.5 4.2e-26 91.7 12.5 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase GREB1 PF15782.5 CAM45610.1 - 0.13 9.4 0.8 0.18 8.9 0.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CENP-X PF09415.10 CAM45610.1 - 0.2 12.0 1.8 3.7 7.9 0.0 2.5 2 0 0 2 2 2 0 CENP-S associating Centromere protein X Myc_N PF01056.18 CAM45610.1 - 0.76 9.6 6.2 1.2 9.0 6.2 1.2 1 0 0 1 1 1 0 Myc amino-terminal region CAML PF14963.6 CAM45610.1 - 1.7 8.7 5.1 3.2 7.8 5.1 1.3 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand U-box PF04564.15 CAM45611.2 - 5.2e-05 23.3 0.0 0.00013 22.1 0.0 1.6 1 0 0 1 1 1 1 U-box domain Lectin_leg-like PF03388.13 CAM45612.1 - 8.1e-43 146.4 0.0 1.1e-42 145.9 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 CAM45612.1 - 7.9e-09 35.8 0.0 1.3e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial lectin TFIIA PF03153.13 CAM45612.1 - 0.038 14.0 11.7 0.047 13.7 11.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ASD2 PF08687.11 CAM45612.1 - 0.32 10.5 4.1 0.46 10.0 4.1 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Herpes_BLLF1 PF05109.13 CAM45612.1 - 4 5.3 11.6 5.4 4.9 11.6 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Peptidase_M24 PF00557.24 CAM45613.1 - 2.2e-15 56.9 0.5 1.7e-14 54.0 0.2 2.4 1 1 1 2 2 2 2 Metallopeptidase family M24 PSP1 PF04468.12 CAM45614.1 - 3e-21 75.5 0.0 7.2e-21 74.3 0.0 1.7 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Kinesin PF00225.23 CAM45615.1 - 1e-33 116.7 0.0 8.1e-10 38.1 0.0 5.1 4 1 0 4 4 4 4 Kinesin motor domain Microtub_bd PF16796.5 CAM45615.1 - 1.8e-05 24.7 0.0 0.00051 20.0 0.0 2.6 2 1 0 2 2 2 1 Microtubule binding ArfGap PF01412.18 CAM45616.1 - 7.6e-29 100.2 0.1 1.3e-28 99.4 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PRIMA1 PF16101.5 CAM45616.1 - 3.5 7.7 9.2 0.43 10.6 3.8 2.2 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 ADH_zinc_N PF00107.26 CAM45617.1 - 1.8e-12 47.4 0.0 3.5e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CAM45617.1 - 5.6e-11 42.3 0.1 2.9e-10 40.0 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CAM45617.1 - 3.8e-08 34.4 0.0 7.7e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ubiquitin PF00240.23 CAM45618.1 - 8.2e-10 38.3 0.0 1.6e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CAM45618.1 - 0.0002 21.1 0.0 0.00047 19.9 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CAM45618.1 - 0.0018 18.8 0.4 0.0099 16.4 0.0 2.4 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CAM45618.1 - 0.0041 17.2 0.1 0.018 15.2 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CAM45618.1 - 0.092 13.2 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain RLL PF10036.9 CAM45618.1 - 1.2 8.9 6.3 0.23 11.3 2.4 1.7 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein Anoctamin PF04547.12 CAM45619.1 - 4.1e-70 236.9 0.0 5.4e-70 236.5 0.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel C2 PF00168.30 CAM45621.2 - 6.3e-20 71.4 0.0 1.4e-19 70.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain DSPc PF00782.20 CAM45622.1 - 2.8e-08 33.7 0.0 5.2e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Pkinase PF00069.25 CAM45623.1 - 3e-40 138.2 0.0 9.9e-33 113.6 0.0 3.1 2 1 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CAM45623.1 - 2.2e-16 60.0 0.0 4e-15 55.8 0.0 2.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAM45623.1 - 2.9e-05 23.6 0.0 9.8e-05 21.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like CTU2 PF10288.9 CAM45624.2 - 7.3e-05 23.0 2.9 0.00018 21.7 0.2 2.8 2 0 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 SUZ PF12752.7 CAM45624.2 - 1.4 9.7 5.3 0.32 11.8 0.5 2.5 2 0 0 2 2 2 0 SUZ domain SR-25 PF10500.9 CAM45625.1 - 1.6 8.3 16.6 2.8 7.5 16.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Complex1_LYR_2 PF13233.6 CAM45626.1 - 6.3e-06 26.9 0.0 1e-05 26.2 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 CAM45626.1 - 0.0037 17.3 0.1 2.2 8.4 0.0 2.6 2 0 0 2 2 2 2 Complex 1 protein (LYR family) Peptidase_M16 PF00675.20 CAM45631.2 - 1.6e-05 24.9 0.0 0.00013 21.9 0.0 2.4 1 1 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CAM45631.2 - 0.024 14.7 0.0 0.15 12.0 0.0 2.3 2 1 0 2 2 2 0 Peptidase M16 inactive domain Kinocilin PF15033.6 CAM45631.2 - 0.05 13.2 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Kinocilin protein Flagellin_IN PF07196.13 CAM45631.2 - 0.12 12.6 0.1 0.3 11.3 0.1 1.6 1 0 0 1 1 1 0 Flagellin hook IN motif DUF3381 PF11861.8 CAM45632.1 - 0.061 13.1 0.0 0.061 13.1 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3381) Swi3 PF07962.12 CAM45633.1 - 0.069 13.1 0.1 0.16 12.0 0.0 1.7 2 0 0 2 2 2 0 Replication Fork Protection Component Swi3 LRR_6 PF13516.6 CAM45635.1 - 2.1e-07 30.4 3.8 0.082 13.0 0.0 3.8 3 0 0 3 3 3 2 Leucine Rich repeat LRR_8 PF13855.6 CAM45635.1 - 0.00044 20.0 3.0 0.00044 20.0 3.0 2.2 2 1 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 CAM45635.1 - 0.00097 19.5 2.6 0.00097 19.5 2.6 2.8 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CAM45635.1 - 0.0061 16.9 3.9 0.52 11.1 0.5 3.5 2 0 0 2 2 2 1 Leucine Rich Repeat Ax_dynein_light PF10211.9 CAM45636.2 - 0.00018 21.5 4.6 0.00018 21.5 4.6 2.2 2 0 0 2 2 2 1 Axonemal dynein light chain DUF4201 PF13870.6 CAM45636.2 - 0.04 13.7 5.5 0.1 12.4 5.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) GvpG PF05120.12 CAM45636.2 - 0.37 10.8 1.9 1.3 9.1 1.9 1.9 1 0 0 1 1 1 0 Gas vesicle protein G PXA PF02194.15 CAM45636.2 - 2.6 8.0 4.6 7.9 6.4 4.6 1.8 1 0 0 1 1 1 0 PXA domain Cluap1 PF10234.9 CAM45636.2 - 2.9 7.2 12.7 0.023 14.1 3.7 2.0 2 0 0 2 2 2 0 Clusterin-associated protein-1 Atg14 PF10186.9 CAM45636.2 - 2.9 6.9 17.0 0.02 14.0 5.6 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMF_TATA_bd PF12325.8 CAM45636.2 - 4.1 7.6 14.6 0.59 10.4 6.2 3.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 CAM45636.2 - 7.6 5.3 13.6 0.11 11.4 5.0 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Glyco_transf_25 PF01755.17 CAM45637.1 - 1.1e-18 67.8 0.0 1.8e-17 63.9 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) TRM PF02005.16 CAM45638.1 - 1.1e-93 314.4 0.0 2.1e-44 152.3 0.0 3.1 3 0 0 3 3 3 3 N2,N2-dimethylguanosine tRNA methyltransferase Actin PF00022.19 CAM45639.2 - 2.9e-110 368.7 0.0 3.1e-109 365.3 0.0 2.3 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CAM45639.2 - 0.21 10.4 0.0 11 4.7 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein AAA PF00004.29 CAM45640.1 - 2.7e-37 128.2 0.0 4.6e-37 127.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAM45640.1 - 2.1e-08 33.8 0.4 4.7e-08 32.7 0.4 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 CAM45640.1 - 8.6e-06 26.1 2.4 0.027 14.7 0.1 3.3 2 1 1 3 3 3 2 AAA domain Vps4_C PF09336.10 CAM45640.1 - 9e-06 25.6 0.0 2.4e-05 24.2 0.0 1.7 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 CAM45640.1 - 1.6e-05 24.7 0.0 2.8e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain LisH_TPL PF17814.1 CAM45640.1 - 0.00028 20.5 0.6 0.00062 19.4 0.6 1.6 1 0 0 1 1 1 1 LisH-like dimerisation domain AAA_24 PF13479.6 CAM45640.1 - 0.00031 20.5 0.0 0.0006 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CAM45640.1 - 0.0005 20.5 0.0 0.0015 18.9 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 CAM45640.1 - 0.00082 18.7 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_25 PF13481.6 CAM45640.1 - 0.0022 17.6 0.1 0.14 11.7 0.1 2.4 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CAM45640.1 - 0.0045 16.7 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 CAM45640.1 - 0.0087 16.6 0.0 0.025 15.1 0.0 1.8 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.14 CAM45640.1 - 0.012 15.6 0.1 0.03 14.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CAM45640.1 - 0.012 15.7 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 CAM45640.1 - 0.015 14.7 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 CAM45640.1 - 0.017 15.2 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CAM45640.1 - 0.017 14.7 0.0 0.044 13.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 CAM45640.1 - 0.03 13.7 0.1 0.69 9.2 0.1 2.2 1 1 1 2 2 2 0 KaiC RNA_helicase PF00910.22 CAM45640.1 - 0.031 14.7 0.0 0.063 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.16 CAM45640.1 - 0.052 13.0 0.1 0.17 11.3 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.6 CAM45640.1 - 0.053 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mesothelin PF06060.12 CAM45640.1 - 0.056 11.6 0.0 0.09 11.0 0.0 1.2 1 0 0 1 1 1 0 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) AAA_28 PF13521.6 CAM45640.1 - 0.057 13.7 0.1 0.34 11.1 0.0 2.3 3 0 0 3 3 3 0 AAA domain LisH PF08513.11 CAM45640.1 - 0.061 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 LisH A_deaminase PF00962.22 CAM45642.2 - 1.3e-88 297.5 0.0 2.2e-83 280.3 0.0 2.4 2 0 0 2 2 2 2 Adenosine/AMP deaminase BRF1 PF07741.13 CAM45643.1 - 0.028 14.8 2.2 0.028 14.8 2.2 4.3 3 1 1 4 4 4 0 Brf1-like TBP-binding domain NKAIN PF05640.14 CAM45645.1 - 0.018 14.3 0.7 0.051 12.8 0.1 1.9 2 0 0 2 2 2 0 Na,K-Atpase Interacting protein CAP59_mtransfer PF11735.8 CAM45646.1 - 3.6e-55 187.3 0.0 1.3e-53 182.2 0.0 2.5 2 1 0 2 2 2 2 Cryptococcal mannosyltransferase 1 Peptidase_S8 PF00082.22 CAM45649.1 - 4.8e-26 91.7 0.1 3.5e-23 82.3 0.0 3.2 2 1 0 2 2 2 2 Subtilase family Dpy-30 PF05186.13 CAM45650.1 - 2.2e-07 30.4 0.4 5e-07 29.3 0.4 1.6 1 0 0 1 1 1 1 Dpy-30 motif FAD_binding_6 PF00970.24 CAM45651.1 - 1e-30 106.0 0.0 1.5e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CAM45651.1 - 3.6e-28 98.4 0.0 4.9e-27 94.7 0.0 2.4 1 1 2 3 3 3 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CAM45651.1 - 0.0017 18.5 0.0 0.037 14.1 0.0 2.4 2 0 0 2 2 2 1 Ferric reductase NAD binding domain DUF870 PF05912.11 CAM45651.1 - 0.2 11.7 0.0 0.4 10.7 0.0 1.4 1 0 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF870) AAA PF00004.29 CAM45652.1 - 1.6e-42 145.0 0.0 2.7e-42 144.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAM45652.1 - 6.3e-09 35.5 0.5 1.3e-08 34.5 0.5 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 CAM45652.1 - 5e-07 29.6 0.1 1e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 CAM45652.1 - 3.2e-06 27.3 0.0 6.3e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CAM45652.1 - 5.5e-06 26.4 0.1 2e-05 24.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Prot_ATP_OB_N PF17758.1 CAM45652.1 - 2.3e-05 24.0 0.1 7.4e-05 22.3 0.0 1.9 2 0 0 2 2 1 1 Proteasomal ATPase OB N-terminal domain AAA_16 PF13191.6 CAM45652.1 - 3.2e-05 24.4 0.2 0.0032 17.9 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CAM45652.1 - 4.5e-05 23.7 0.4 0.022 15.0 0.4 2.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 CAM45652.1 - 0.00047 19.4 0.0 0.00074 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 CAM45652.1 - 0.0014 18.4 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CAM45652.1 - 0.0031 18.1 0.0 0.0061 17.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CAM45652.1 - 0.0059 16.8 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 CAM45652.1 - 0.012 15.5 0.0 0.029 14.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 CAM45652.1 - 0.024 14.0 0.2 0.31 10.4 0.1 2.2 1 1 1 2 2 2 0 KaiC RNA_helicase PF00910.22 CAM45652.1 - 0.026 14.9 0.0 0.07 13.5 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA_28 PF13521.6 CAM45652.1 - 0.033 14.4 0.1 0.083 13.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 CAM45652.1 - 0.036 14.1 0.0 0.069 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CAM45652.1 - 0.05 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.6 CAM45652.1 - 0.053 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CAM45652.1 - 0.058 13.1 0.4 0.25 11.1 0.2 2.3 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 CAM45652.1 - 0.077 12.2 0.0 0.15 11.2 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 CAM45652.1 - 0.096 12.6 0.2 0.98 9.3 0.1 2.2 1 1 1 2 2 2 0 NACHT domain TIP49 PF06068.13 CAM45652.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 CAM45652.1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 CAM45652.1 - 0.15 11.2 0.0 0.96 8.6 0.0 2.3 4 0 0 4 4 4 0 NB-ARC domain AAA_25 PF13481.6 CAM45652.1 - 0.22 11.1 0.8 5.1 6.6 0.3 2.5 1 1 1 2 2 2 0 AAA domain tRNA-synt_1 PF00133.22 CAM45653.2 - 7.8e-29 100.4 0.0 6.7e-10 37.9 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CAM45653.2 - 3.3e-20 72.2 0.0 5.3e-10 38.6 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CAM45653.2 - 4.4e-12 46.2 0.3 1.1e-11 45.0 0.3 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 CAM45653.2 - 2.1e-07 30.6 0.0 4.7e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain YxiJ PF14176.6 CAM45653.2 - 0.0096 16.4 0.3 0.85 10.1 0.3 2.6 2 0 0 2 2 2 1 YxiJ-like protein Clathrin_H_link PF13838.6 CAM45654.1 - 1.6 8.7 7.1 3.3 7.7 0.5 2.8 2 0 0 2 2 2 0 Clathrin-H-link RNA_pol_N PF01194.17 CAM45655.1 - 1.5e-25 89.3 1.5 1.8e-25 89.0 1.5 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit DUF155 PF02582.14 CAM45656.1 - 1e-38 133.2 0.0 1.5e-38 132.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF780 PF05611.11 CAM45656.1 - 0.31 11.8 16.8 0.074 13.8 8.3 2.6 2 0 0 2 2 2 0 Caenorhabditis elegans protein of unknown function (DUF780) Abhydrolase_6 PF12697.7 CAM45657.1 - 1.1e-13 52.3 2.4 1.6e-12 48.5 2.4 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CAM45657.1 - 4.8e-10 39.5 1.2 5.6e-05 22.9 0.8 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CAM45657.1 - 9.2e-05 21.8 0.1 0.0011 18.2 0.1 2.4 3 0 0 3 3 3 1 Serine aminopeptidase, S33 LCAT PF02450.15 CAM45657.1 - 0.011 14.9 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Esterase PF00756.20 CAM45657.1 - 0.019 14.6 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Thioesterase PF00975.20 CAM45657.1 - 0.081 13.0 0.3 3.4 7.7 0.0 2.9 2 2 0 2 2 2 0 Thioesterase domain Abhydro_lipase PF04083.16 CAM45657.1 - 0.095 12.3 0.1 0.27 10.8 0.0 1.8 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region LIDHydrolase PF10230.9 CAM45657.1 - 0.097 12.2 0.0 1.1 8.7 0.0 2.1 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase PGAP1 PF07819.13 CAM45657.1 - 0.13 11.9 0.1 0.4 10.3 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein Endonuc-BglII PF09195.11 CAM45658.1 - 0.067 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease BglII Tctex-1 PF03645.13 CAM45659.1 - 1.5e-23 83.0 0.0 2.4e-23 82.3 0.0 1.3 1 1 0 1 1 1 1 Tctex-1 family Rio2_N PF09202.11 CAM45659.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.6 2 0 0 2 2 2 0 Rio2, N-terminal Adenylsucc_synt PF00709.21 CAM45660.1 - 3.1e-92 309.7 0.0 3.9e-92 309.3 0.0 1.1 1 0 0 1 1 1 1 Adenylosuccinate synthetase Ribosomal_L27 PF01016.19 CAM45661.1 - 0.12 12.4 0.4 0.23 11.5 0.4 1.6 1 1 0 1 1 1 0 Ribosomal L27 protein RsgA_N PF16745.5 CAM45661.1 - 0.17 11.7 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 RsgA N-terminal domain Nucleoside_tran PF01733.18 CAM45662.1 - 2.1e-28 99.6 8.4 2.9e-26 92.6 8.4 2.5 1 1 0 1 1 1 1 Nucleoside transporter Ribosomal_S4e PF00900.20 CAM45663.1 - 6e-25 86.9 0.0 9.6e-25 86.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.12 CAM45663.1 - 8.7e-18 64.2 4.7 1.9e-17 63.0 4.7 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain 40S_S4_C PF16121.5 CAM45663.1 - 1.4e-16 59.9 0.0 2.5e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus S4 PF01479.25 CAM45663.1 - 3.3e-07 29.9 0.1 1.1e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 S4 domain KOW PF00467.29 CAM45663.1 - 2.3e-06 27.3 0.7 2.3e-06 27.3 0.7 1.9 2 0 0 2 2 2 1 KOW motif TPK_catalytic PF04263.16 CAM45664.2 - 1.3e-11 44.5 0.0 1.4e-05 25.1 0.0 3.1 2 1 0 2 2 2 2 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 CAM45664.2 - 1.6e-06 27.7 0.0 4.4e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain TetR_C_6 PF13977.6 CAM45664.2 - 0.029 14.6 0.7 0.054 13.7 0.7 1.4 1 0 0 1 1 1 0 BetI-type transcriptional repressor, C-terminal PARP PF00644.20 CAM45664.2 - 0.14 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain BatA PF07584.11 CAM45665.2 - 0.036 14.4 0.0 0.054 13.9 0.0 1.3 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal Herpes_LMP1 PF05297.11 CAM45665.2 - 0.038 13.2 0.0 0.042 13.0 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Ac76 PF05814.11 CAM45665.2 - 0.21 11.6 0.4 0.29 11.2 0.4 1.2 1 0 0 1 1 1 0 Orf76 (Ac76) DUF2561 PF10812.8 CAM45666.1 - 0.026 14.5 0.0 0.032 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) DPM2 PF07297.12 CAM45666.1 - 0.056 13.7 0.1 0.09 13.1 0.1 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) UPF0370 PF13980.6 CAM45666.1 - 0.14 12.2 2.2 1.7 8.7 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) Insulin_TMD PF17870.1 CAM45666.1 - 0.18 11.9 1.7 0.31 11.1 1.7 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Endonuclease_NS PF01223.23 CAM45667.1 - 3.6e-18 66.2 0.0 1.3e-17 64.4 0.0 1.8 2 0 0 2 2 2 1 DNA/RNA non-specific endonuclease ATP_bind_1 PF03029.17 CAM45668.1 - 1.4e-59 201.8 0.0 9.6e-59 199.1 0.0 1.9 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein SRP54 PF00448.22 CAM45668.1 - 5.6e-05 22.9 0.0 0.0015 18.2 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 CAM45668.1 - 7.6e-05 22.8 0.0 0.00014 21.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CAM45668.1 - 8.8e-05 22.9 0.0 0.00017 22.0 0.0 1.8 2 1 0 2 2 1 1 AAA ATPase domain GTP_EFTU PF00009.27 CAM45668.1 - 0.00011 21.8 0.0 0.14 11.7 0.0 2.7 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 CAM45668.1 - 0.00052 19.8 0.0 0.001 18.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CAM45668.1 - 0.00069 19.5 0.1 2.2 8.1 0.1 3.1 2 1 0 2 2 2 2 RsgA GTPase cobW PF02492.19 CAM45668.1 - 0.002 17.7 0.6 0.27 10.8 0.0 2.5 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 CAM45668.1 - 0.0027 17.2 0.0 0.24 10.8 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_33 PF13671.6 CAM45668.1 - 0.0033 17.6 0.0 0.0053 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CAM45668.1 - 0.0095 16.2 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CAM45668.1 - 0.01 15.6 0.0 0.027 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CAM45668.1 - 0.01 15.3 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 CAM45668.1 - 0.012 14.8 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 CAM45668.1 - 0.019 14.9 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain SRPRB PF09439.10 CAM45668.1 - 0.02 14.4 0.0 0.75 9.2 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit MeaB PF03308.16 CAM45668.1 - 0.02 13.9 0.1 0.86 8.5 0.0 2.8 2 2 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 CAM45668.1 - 0.023 14.9 0.0 0.34 11.1 0.0 2.3 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 CAM45668.1 - 0.025 14.9 0.2 0.046 14.1 0.2 1.5 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CAM45668.1 - 0.042 14.4 0.0 0.073 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 CAM45668.1 - 0.05 13.2 0.1 2.3 7.8 0.0 2.4 2 1 0 2 2 2 0 Ras family Zeta_toxin PF06414.12 CAM45668.1 - 0.066 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DLIC PF05783.11 CAM45668.1 - 0.076 11.8 0.1 0.28 10.0 0.0 1.7 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA PF00004.29 CAM45668.1 - 0.081 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 CAM45668.1 - 0.089 12.5 0.0 0.57 9.9 0.0 2.2 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 CAM45668.1 - 0.096 12.6 0.2 0.32 10.9 0.2 2.0 1 1 0 1 1 1 0 NTPase Septin PF00735.18 CAM45668.1 - 0.1 11.9 0.1 0.51 9.6 0.1 2.2 1 1 0 1 1 1 0 Septin AAA_5 PF07728.14 CAM45668.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MobB PF03205.14 CAM45668.1 - 0.15 12.0 0.0 0.34 10.8 0.0 1.6 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B G-alpha PF00503.20 CAM45668.1 - 0.16 11.1 0.0 4.1 6.5 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit DRIM PF07539.12 CAM45669.1 - 0.11 10.8 0.0 0.15 10.3 0.0 1.1 1 0 0 1 1 1 0 Down-regulated in metastasis Complex1_LYR_1 PF13232.6 CAM45670.1 - 3.4e-41 139.8 1.7 5.1e-41 139.2 1.7 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 CAM45670.1 - 2.8e-05 24.1 1.0 4.2e-05 23.5 0.2 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) DUF4771 PF15995.5 CAM45670.1 - 0.0065 16.7 0.8 0.011 16.0 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4771) DUF5075 PF16825.5 CAM45671.1 - 9.2e-08 32.0 0.2 2.8e-07 30.4 0.2 1.9 1 1 0 1 1 1 1 IGP family C-type lectin domain DUF3742 PF12553.8 CAM45671.1 - 0.042 14.0 0.1 0.087 12.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) DUF5075 PF16825.5 CAM45672.1 - 6.6e-11 42.2 3.3 1.2e-10 41.3 3.3 1.5 1 1 0 1 1 1 1 IGP family C-type lectin domain Ferlin_C PF16165.5 CAM45672.1 - 0.018 15.0 0.3 0.033 14.2 0.3 1.4 1 0 0 1 1 1 0 Ferlin C-terminus DUF4492 PF14899.6 CAM45672.1 - 0.077 12.9 2.7 0.16 11.9 2.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) PRIMA1 PF16101.5 CAM45672.1 - 4 7.5 7.0 0.54 10.3 1.8 2.1 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 TMIE PF16038.5 CAM45672.1 - 6.6 6.7 5.1 12 5.9 5.1 1.3 1 0 0 1 1 1 0 TMIE protein TPR_16 PF13432.6 CAM45674.1 - 0.027 15.1 1.5 0.027 15.1 1.5 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Dpy-30 PF05186.13 CAM45675.1 - 4.4e-13 48.7 0.4 8.8e-13 47.7 0.4 1.5 1 0 0 1 1 1 1 Dpy-30 motif Hydin_ADK PF17213.3 CAM45675.1 - 5.4e-05 23.6 0.0 5.4e-05 23.6 0.0 2.3 3 0 0 3 3 3 1 Hydin Adenylate kinase-like domain AAA PF00004.29 CAM45675.1 - 0.082 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 CAM45675.1 - 0.089 13.2 0.0 2.7 8.4 0.0 3.1 2 1 1 3 3 3 0 AAA domain Fib_alpha PF08702.10 CAM45676.2 - 0.63 10.2 4.0 2.1 8.5 0.4 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 CAM45676.2 - 2.8 8.0 5.2 9.5 6.3 0.3 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sin_N PF04801.13 CAM45677.2 - 5.9e-77 259.7 0.4 9.9e-77 259.0 0.2 1.4 2 0 0 2 2 2 1 Sin-like protein conserved region Laminin_I PF06008.14 CAM45677.2 - 0.071 12.8 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 Laminin Domain I EMP70 PF02990.16 CAM45678.1 - 3.8e-107 359.1 15.0 5.9e-107 358.5 15.0 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 LRR_4 PF12799.7 CAM45683.1 - 9.3e-09 35.4 10.6 3.3e-07 30.5 2.5 3.4 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAM45683.1 - 6.8e-05 22.5 5.6 6.8e-05 22.5 5.6 2.4 2 0 0 2 2 2 1 Leucine rich repeat LRR_9 PF14580.6 CAM45683.1 - 0.14 11.7 0.1 0.24 10.9 0.1 1.3 1 0 0 1 1 1 0 Leucine-rich repeat LRR_1 PF00560.33 CAM45683.1 - 0.7 10.7 5.2 38 5.4 0.0 4.2 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 CAM45683.1 - 0.87 9.8 7.8 9.8 6.5 0.3 3.5 3 1 1 4 4 4 0 Leucine Rich repeat SUIM_assoc PF16619.5 CAM45684.2 - 0.13 12.3 6.0 0.21 11.7 1.8 3.2 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 EF-hand_1 PF00036.32 CAM45685.1 - 3.5e-24 82.5 0.0 4.2e-06 25.9 0.0 5.2 5 0 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 CAM45685.1 - 1.5e-21 74.4 0.9 0.00027 20.6 0.1 5.1 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 CAM45685.1 - 2.5e-21 75.9 0.0 5.4e-10 39.6 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CAM45685.1 - 5.7e-16 57.2 1.0 2.8e-06 26.6 0.0 3.8 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CAM45685.1 - 1.4e-14 53.6 0.1 0.0004 20.2 0.0 4.3 3 2 2 5 5 5 3 EF-hand domain pair EF-hand_9 PF14658.6 CAM45685.1 - 0.00018 21.8 0.0 0.19 12.1 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain PAH PF02671.21 CAM45685.1 - 0.026 14.7 0.0 0.13 12.4 0.0 2.2 2 0 0 2 2 2 0 Paired amphipathic helix repeat EF-hand_10 PF14788.6 CAM45685.1 - 0.043 13.7 0.0 0.43 10.5 0.1 2.6 2 1 1 3 3 3 0 EF hand HECT PF00632.25 CAM45686.2 - 3.9e-43 148.1 0.0 7.3e-43 147.2 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 CAM45686.2 - 1.6e-26 92.7 0.4 3.4e-10 40.1 0.0 3.9 3 0 0 3 3 3 3 SPRY domain Ran_BP1 PF00638.18 CAM45687.1 - 1.2e-25 90.1 1.6 1.6e-25 89.7 1.6 1.1 1 0 0 1 1 1 1 RanBP1 domain Polyketide_cyc2 PF10604.9 CAM45687.1 - 0.025 14.9 0.3 0.03 14.6 0.3 1.2 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport DRMBL PF07522.14 CAM45688.1 - 0.15 12.2 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 DNA repair metallo-beta-lactamase PIN_4 PF13638.6 CAM45689.1 - 9.7e-17 61.5 0.0 2.1e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 PIN domain DUF294_C PF10335.9 CAM45689.1 - 0.07 12.9 0.2 1 9.2 0.0 2.4 2 0 0 2 2 2 0 Putative nucleotidyltransferase substrate binding domain Metallophos PF00149.28 CAM45690.1 - 8.5e-23 81.9 0.0 1.4e-22 81.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase LRR_4 PF12799.7 CAM45692.1 - 3.5e-09 36.8 17.5 0.063 13.7 0.5 6.2 3 1 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CAM45692.1 - 1.7 8.9 5.2 48 4.4 0.1 5.2 4 0 0 4 4 4 0 Leucine Rich repeat SNAP PF14938.6 CAM45693.2 - 2.7e-05 23.7 16.8 0.0031 17.0 7.0 3.1 2 1 1 3 3 3 2 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 CAM45693.2 - 0.026 14.6 9.4 0.09 12.9 1.2 4.4 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 CAM45693.2 - 0.036 14.4 0.1 0.036 14.4 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 CAM45693.2 - 0.038 14.6 8.0 0.68 10.6 0.9 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CAM45693.2 - 0.063 13.1 1.5 6.7 6.7 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CAM45693.2 - 2.5 9.1 8.0 5.6 8.1 0.3 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Trimer_CC PF08954.11 CAM45695.2 - 0.064 12.8 1.5 0.42 10.2 1.5 2.5 1 0 0 1 1 1 0 Trimerisation motif Amastin PF07344.11 CAM45696.1 - 5.8e-61 204.9 9.9 7.2e-61 204.6 9.9 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.6 CAM45696.1 - 0.019 14.7 1.1 0.019 14.7 1.1 2.6 1 1 2 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF805 PF05656.14 CAM45696.1 - 0.043 14.2 6.8 0.043 14.2 2.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF805) DUF2781 PF10914.8 CAM45696.1 - 2.3 8.6 10.6 5.2 7.5 10.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2781) START PF01852.19 CAM45697.1 - 0.00043 19.8 0.0 0.00073 19.0 0.0 1.3 1 0 0 1 1 1 1 START domain PseudoU_synth_1 PF01416.20 CAM45698.1 - 2.2e-10 41.0 0.1 3.9e-07 30.5 0.0 3.4 2 1 0 2 2 2 2 tRNA pseudouridine synthase WD40 PF00400.32 CAM45699.1 - 1.2e-16 60.7 2.6 0.0052 17.6 0.0 7.5 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.8 CAM45699.1 - 0.0036 16.0 0.0 0.34 9.5 0.0 2.6 3 0 0 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CAM45699.1 - 0.0091 16.3 0.0 7.4 6.9 0.0 3.8 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Mon1 PF03164.14 CAM45700.1 - 4.5e-32 111.6 0.0 6.2e-12 45.3 0.0 3.0 3 0 0 3 3 3 3 Trafficking protein Mon1 PhoLip_ATPase_C PF16212.5 CAM45701.2 - 6.8e-67 225.8 20.2 6.8e-67 225.8 20.2 2.2 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CAM45701.2 - 9.2e-24 82.9 6.9 2.3e-23 81.7 3.8 3.1 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 CAM45701.2 - 4.2e-10 39.4 3.8 7.4e-10 38.6 0.0 3.3 3 1 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 CAM45701.2 - 3.2e-09 36.7 0.0 3e-08 33.6 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CAM45701.2 - 5.1e-09 36.7 0.0 3.5e-05 24.2 0.1 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CAM45701.2 - 0.028 14.2 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase NIF PF03031.18 CAM45702.1 - 0.14 11.9 0.0 1.2 8.9 0.0 2.1 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase PhoLip_ATPase_C PF16212.5 CAM45703.1 - 2.4e-67 227.3 19.6 2.4e-67 227.3 19.6 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CAM45703.1 - 1.6e-23 82.2 6.3 9.7e-23 79.6 4.1 3.3 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 CAM45703.1 - 6.1e-10 38.9 0.0 6.1e-10 38.9 0.0 3.2 3 1 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 CAM45703.1 - 2.1e-09 37.4 0.0 2.4e-08 34.0 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CAM45703.1 - 2.7e-08 34.4 0.1 0.00019 21.8 0.1 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CAM45703.1 - 0.025 14.3 0.0 0.06 13.1 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Gtr1_RagA PF04670.12 CAM45705.1 - 1.4e-91 306.0 0.0 1.8e-91 305.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 CAM45705.1 - 2.1e-06 27.9 0.0 1.6e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CAM45705.1 - 3.4e-05 23.5 0.0 0.00014 21.5 0.0 2.0 3 0 0 3 3 3 1 Ras family Arf PF00025.21 CAM45705.1 - 0.00033 20.2 0.0 0.002 17.6 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family Metallophos PF00149.28 CAM45706.1 - 5.7e-23 82.5 0.0 1e-22 81.7 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CAM45706.1 - 0.073 13.5 0.0 0.31 11.5 0.0 2.0 2 0 0 2 2 2 0 Serine-threonine protein phosphatase N-terminal domain UQ_con PF00179.26 CAM45707.1 - 3e-15 56.1 0.0 3.2e-15 56.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CAM45707.1 - 0.0024 18.1 0.0 0.0027 18.0 0.0 1.2 1 0 0 1 1 1 1 RWD domain LD_cluster2 PF18163.1 CAM45707.1 - 0.03 13.9 0.1 0.038 13.5 0.1 1.1 1 0 0 1 1 1 0 SLOG cluster2 BRE PF06113.12 CAM45707.1 - 0.15 10.9 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) Tcp10_C PF07202.13 CAM45708.1 - 5.6e-25 88.3 1.5 8.3e-25 87.7 0.1 2.0 2 0 0 2 2 2 1 T-complex protein 10 C-terminus PSI_PsaF PF02507.15 CAM45708.1 - 0.038 13.8 0.5 0.11 12.3 0.5 1.7 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III Seadorna_VP6 PF07407.11 CAM45708.1 - 0.18 10.7 0.5 0.29 10.0 0.5 1.2 1 0 0 1 1 1 0 Seadornavirus VP6 protein FAP206 PF12018.8 CAM45708.1 - 2.6 7.5 8.2 6 6.3 8.2 1.6 1 0 0 1 1 1 0 Domain of unknown function MtrB PF05440.12 CAM45709.2 - 0.12 12.8 0.2 4 7.9 0.0 3.6 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF2890 PF11081.8 CAM45709.2 - 0.2 11.8 10.2 0.89 9.6 2.9 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) DUF4145 PF13643.6 CAM45709.2 - 1.5 9.0 5.3 27 5.0 0.2 5.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4145) Kinesin PF00225.23 CAM45710.1 - 3.7e-92 308.8 0.0 5.3e-92 308.3 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CAM45710.1 - 2e-16 60.3 0.0 4.1e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding SAM_1 PF00536.30 CAM45710.1 - 0.00021 21.7 0.2 0.00021 21.7 0.2 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) BLOC1_2 PF10046.9 CAM45710.1 - 0.066 13.5 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SAM_2 PF07647.17 CAM45710.1 - 0.09 12.9 0.2 0.2 11.8 0.2 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SE PF08491.10 CAM45711.2 - 4.3e-59 199.8 0.0 6.3e-59 199.3 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 CAM45711.2 - 4.3e-08 32.8 0.0 2.9e-07 30.1 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 CAM45711.2 - 0.0045 16.3 0.1 0.0083 15.4 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 CAM45711.2 - 0.027 13.0 0.0 0.039 12.5 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor FAD_oxidored PF12831.7 CAM45711.2 - 0.044 13.1 0.1 0.06 12.7 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CAM45711.2 - 0.064 13.5 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CAM45711.2 - 0.16 11.0 0.0 3.1 6.7 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 CAM45711.2 - 0.17 11.0 0.1 0.35 9.9 0.0 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A BEN PF10523.9 CAM45711.2 - 0.17 12.1 0.1 0.57 10.4 0.0 1.9 2 0 0 2 2 2 0 BEN domain DNA_pol_A PF00476.20 CAM45712.1 - 3.5e-37 128.3 0.2 9.4e-37 126.9 0.1 1.8 2 0 0 2 2 2 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 CAM45712.1 - 2.7e-05 24.0 0.0 7.2e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 3'-5' exonuclease Pkinase PF00069.25 CAM45713.2 - 7.1e-52 176.4 0.0 5.1e-30 104.7 0.0 3.7 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAM45713.2 - 6.1e-21 74.9 0.0 6e-17 61.8 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Haspin_kinase PF12330.8 CAM45713.2 - 0.0016 17.4 0.0 0.0025 16.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CAM45713.2 - 0.012 15.0 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AAA_6 PF12774.7 CAM45714.1 - 5.8e-141 469.2 0.0 7.6e-140 465.5 0.0 2.6 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 CAM45714.1 - 7.7e-133 444.1 0.1 2.8e-131 439.0 0.0 2.8 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 CAM45714.1 - 1.1e-111 373.7 4.6 1.1e-111 373.7 4.6 3.2 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 CAM45714.1 - 7.7e-96 320.4 0.4 2.2e-95 318.9 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 MT PF12777.7 CAM45714.1 - 7.6e-84 281.7 10.7 1.7e-83 280.6 10.7 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.7 CAM45714.1 - 9.1e-83 276.7 0.1 9.1e-83 276.7 0.1 3.1 3 0 0 3 3 3 1 ATP-binding dynein motor region Dynein_C PF18199.1 CAM45714.1 - 5e-76 255.8 0.1 1.7e-75 254.1 0.1 2.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 CAM45714.1 - 4e-68 228.5 0.5 3.2e-63 212.5 0.1 3.9 4 0 0 4 4 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CAM45714.1 - 6.3e-46 156.2 0.0 1.8e-45 154.7 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CAM45714.1 - 3.7e-36 123.8 0.0 9.9e-22 77.3 0.0 4.7 4 0 0 4 4 4 2 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 CAM45714.1 - 3.1e-26 91.5 0.2 1.9e-25 89.0 0.2 2.5 1 0 0 1 1 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 CAM45714.1 - 8.3e-24 84.1 0.2 3.3e-23 82.2 0.2 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CAM45714.1 - 1.2e-20 73.9 0.1 1.7e-07 31.3 0.0 5.8 5 0 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CAM45714.1 - 4.5e-08 33.7 0.5 0.04 14.5 0.0 6.4 6 0 0 6 6 5 1 AAA domain AAA PF00004.29 CAM45714.1 - 3e-06 27.7 0.0 0.18 12.3 0.0 3.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CAM45714.1 - 4.8e-05 23.6 0.3 3.8 7.8 0.0 5.0 5 0 0 5 5 3 1 AAA domain AAA_16 PF13191.6 CAM45714.1 - 0.00017 22.0 9.4 0.29 11.5 0.1 6.3 6 1 1 7 7 5 1 AAA ATPase domain AAA_19 PF13245.6 CAM45714.1 - 0.00025 21.4 0.6 0.66 10.3 0.0 3.8 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 CAM45714.1 - 0.0068 15.8 0.2 0.71 9.2 0.0 3.7 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CAM45714.1 - 0.033 14.6 1.5 69 3.9 0.0 4.8 4 0 0 4 4 4 0 RNA helicase TsaE PF02367.17 CAM45714.1 - 0.039 13.9 0.5 27 4.8 0.1 3.9 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 CAM45714.1 - 0.062 12.4 0.0 0.9 8.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) GP3_package PF16677.5 CAM45714.1 - 0.58 10.3 2.8 3.6 7.8 2.3 2.7 2 0 0 2 2 2 0 DNA-packaging protein gp3 AAA_28 PF13521.6 CAM45714.1 - 0.83 9.9 4.8 26 5.0 0.1 4.2 4 0 0 4 4 3 0 AAA domain Cpn60_TCP1 PF00118.24 CAM45715.1 - 2.5e-163 544.2 7.8 2.8e-163 544.1 7.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GARS_N PF02844.15 CAM45715.1 - 0.093 13.5 0.0 2.3 9.1 0.0 2.8 2 1 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain Ribosomal_L44 PF00935.19 CAM45716.1 - 1.2e-31 109.0 9.1 1.7e-31 108.5 9.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 P5CR_dimer PF14748.6 CAM45717.1 - 6.4e-36 122.7 0.8 1.1e-35 122.0 0.8 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 CAM45717.1 - 1.4e-17 64.1 0.0 3.1e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 CAM45717.1 - 5.9e-05 23.3 0.1 0.00011 22.3 0.1 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 CAM45717.1 - 0.00043 20.3 0.1 0.00083 19.4 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 CAM45717.1 - 0.00061 19.5 0.5 0.0026 17.4 0.4 1.9 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA IlvN PF07991.12 CAM45717.1 - 0.0022 17.6 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 CAM45717.1 - 0.097 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SfLAP PF11139.8 CAM45718.2 - 0.0076 15.7 3.4 0.031 13.7 2.3 2.2 2 0 0 2 2 2 1 Sap, sulfolipid-1-addressing protein Elong_Iki1 PF10483.9 CAM45718.2 - 0.052 13.1 0.0 0.086 12.3 0.0 1.4 1 0 0 1 1 1 0 Elongator subunit Iki1 PMP1_2 PF08114.11 CAM45718.2 - 0.29 10.9 0.0 0.29 10.9 0.0 3.0 3 0 0 3 3 3 0 ATPase proteolipid family LRR_4 PF12799.7 CAM45719.1 - 1.5e-12 47.5 0.0 0.029 14.8 0.0 5.8 5 1 1 6 6 6 4 Leucine Rich repeats (2 copies) Codanin-1_C PF15296.6 CAM45722.2 - 8.6 6.5 8.2 55 3.9 8.2 2.4 1 0 0 1 1 1 0 Codanin-1 C-terminus Ion_trans_2 PF07885.16 CBZ14409.1 - 2.1e-11 43.6 5.4 7.5e-11 41.8 5.4 1.9 1 0 0 1 1 1 1 Ion channel BK_channel_a PF03493.18 CBZ14409.1 - 2.3e-06 27.7 0.0 6.4e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Peptidase_M24_C PF16188.5 CBZ14411.1 - 8.6e-20 70.6 0.0 1.1e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Peptidase_M24 PF00557.24 CBZ14411.1 - 5.6e-10 39.2 1.8 7.7e-10 38.8 1.8 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Torus PF16131.5 CBZ14413.1 - 0.0049 17.6 2.2 1.7 9.4 0.1 2.5 2 0 0 2 2 2 2 Torus domain PDEase_I PF00233.19 CBZ14415.1 - 1.9e-22 80.1 0.3 2.9e-22 79.6 0.3 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase TIR_2 PF13676.6 CBZ14415.1 - 0.15 12.7 0.0 0.41 11.3 0.0 1.7 1 0 0 1 1 1 0 TIR domain MHYT PF03707.16 CBZ14426.1 - 0.33 11.1 8.9 2.3 8.4 3.0 2.6 2 1 0 2 2 2 0 Bacterial signalling protein N terminal repeat SNase PF00565.17 CBZ14427.1 - 4.3e-16 59.3 0.0 6.2e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Ada_Zn_binding PF02805.16 CBZ14427.1 - 0.016 15.2 0.1 0.044 13.8 0.1 1.7 2 0 0 2 2 2 0 Metal binding domain of Ada PLAC8 PF04749.17 CBZ14430.1 - 0.005 17.8 33.9 0.0092 17.0 33.9 1.7 1 1 0 1 1 1 1 PLAC8 family Acetyltransf_13 PF13880.6 CBZ14432.1 - 0.027 14.4 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase PvlArgDC PF01862.16 CBZ14433.1 - 0.15 11.9 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) Sel1 PF08238.12 CBZ14434.1 - 0.00042 20.9 3.4 1.9 9.3 2.8 3.3 2 1 0 2 2 2 2 Sel1 repeat Galactosyl_T PF01762.21 CBZ14436.1 - 0.00013 21.8 0.0 0.0012 18.7 0.0 2.3 2 1 1 3 3 3 1 Galactosyltransferase CAF-1_p150 PF11600.8 CBZ14436.1 - 0.13 12.0 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2572 PF10833.8 CBZ14438.1 - 5.2 6.8 6.7 0.52 10.0 1.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2572) APG6 PF04111.12 CBZ14439.1 - 8e-15 55.3 0.0 1.4e-05 25.1 0.0 3.6 3 1 0 3 3 3 3 Apg6 BARA domain Hist_deacetyl PF00850.19 CBZ14441.1 - 1.8e-57 195.2 0.0 3.1e-57 194.4 0.0 1.4 1 1 0 1 1 1 1 Histone deacetylase domain RHH_5 PF07878.11 CBZ14441.1 - 0.015 15.1 0.1 0.04 13.8 0.1 1.8 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 DUF1126 PF06565.12 CBZ14442.1 - 9.4e-60 199.0 0.0 4e-25 87.7 0.0 3.3 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_5 PF13202.6 CBZ14442.1 - 0.0096 15.4 0.0 0.027 14.0 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 CBZ14442.1 - 0.01 15.4 0.0 0.05 13.2 0.0 2.2 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 CBZ14442.1 - 0.076 13.0 0.0 0.87 9.7 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain Ribosomal_L40e PF01020.17 CBZ14444.1 - 3.5e-24 84.4 11.4 3.5e-24 84.4 11.4 1.8 2 0 0 2 2 2 1 Ribosomal L40e family ubiquitin PF00240.23 CBZ14444.1 - 4.4e-07 29.6 0.1 6.1e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family PRKCSH-like PF12999.7 CBZ14445.1 - 3e-08 33.7 0.9 5.7e-07 29.5 0.0 2.3 2 0 0 2 2 2 2 Glucosidase II beta subunit-like PSP1 PF04468.12 CBZ14448.1 - 3.9e-23 81.5 0.9 6.3e-23 80.9 0.9 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region MORN PF02493.20 CBZ14449.1 - 2.1e-19 68.2 16.8 1e-06 28.3 0.5 4.6 4 0 0 4 4 4 4 MORN repeat BT1 PF03092.16 CBZ14450.1 - 2.2e-253 841.3 6.0 2.5e-253 841.1 6.0 1.0 1 0 0 1 1 1 1 BT1 family Nipped-B_C PF12830.7 CBZ14458.1 - 5.7e-25 88.4 0.3 3.8e-24 85.7 0.1 2.5 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus NODP PF07684.12 CBZ14458.1 - 0.032 14.4 0.1 0.14 12.3 0.1 2.2 1 0 0 1 1 1 0 NOTCH protein Tcp11 PF05794.13 CBZ14458.1 - 0.83 8.7 4.6 10 5.0 2.0 3.3 2 1 0 2 2 2 0 T-complex protein 11 HEAT PF02985.22 CBZ14458.1 - 1.5 9.3 4.8 25 5.5 0.1 4.8 4 0 0 4 4 4 0 HEAT repeat IQ PF00612.27 CBZ14461.1 - 0.25 11.2 3.2 0.17 11.7 0.3 2.3 2 0 0 2 2 2 0 IQ calmodulin-binding motif Ras PF00071.22 CBZ14467.1 - 3.1e-35 121.2 0.0 3.9e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ14467.1 - 4.3e-26 91.5 0.0 6.4e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ14467.1 - 4.7e-09 35.9 0.0 6.6e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBZ14467.1 - 5.2e-06 26.0 0.0 7.2e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 CBZ14467.1 - 0.0044 17.4 0.0 0.066 13.6 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain ATPase PF06745.13 CBZ14467.1 - 0.018 14.4 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 KaiC MMR_HSR1 PF01926.23 CBZ14467.1 - 0.027 14.6 0.0 0.074 13.1 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_7 PF12775.7 CBZ14467.1 - 0.049 13.1 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 CBZ14467.1 - 0.066 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein RsgA_GTPase PF03193.16 CBZ14467.1 - 0.13 12.1 0.0 0.77 9.6 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 CBZ14467.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Na_H_Exchanger PF00999.21 CBZ14470.1 - 1.1e-18 67.2 25.7 1.8e-18 66.5 25.7 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF4181 PF13789.6 CBZ14470.1 - 8.8 6.7 9.6 0.14 12.5 1.2 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4181) Ribosomal_60s PF00428.19 CBZ14476.1 - 2e-20 73.2 13.8 2.4e-20 72.9 13.8 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Arg_repressor_C PF02863.18 CBZ14476.1 - 0.0046 16.8 0.9 0.0046 16.8 0.9 1.8 2 0 0 2 2 2 1 Arginine repressor, C-terminal domain Ribosomal_60s PF00428.19 CBZ14477.1 - 2e-20 73.2 13.8 2.4e-20 72.9 13.8 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Arg_repressor_C PF02863.18 CBZ14477.1 - 0.0046 16.8 0.9 0.0046 16.8 0.9 1.8 2 0 0 2 2 2 1 Arginine repressor, C-terminal domain DHO_dh PF01180.21 CBZ14483.1 - 6.7e-70 235.6 0.0 7.6e-70 235.4 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 CBZ14483.1 - 0.0065 15.5 0.7 0.02 13.9 0.1 1.9 2 0 0 2 2 2 1 FMN-dependent dehydrogenase PcrB PF01884.17 CBZ14483.1 - 0.17 11.3 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 PcrB family Kinesin PF00225.23 CBZ14485.1 - 3.9e-41 141.1 0.0 9.6e-40 136.5 0.0 2.3 1 1 0 1 1 1 1 Kinesin motor domain PH_12 PF16457.5 CBZ14485.1 - 0.12 12.9 0.0 0.34 11.5 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Spc7 PF08317.11 CBZ14485.1 - 1 8.2 4.0 1.8 7.4 4.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Pkinase PF00069.25 CBZ14487.1 - 2e-35 122.4 0.0 2.7e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ14487.1 - 3e-27 95.5 0.1 4.5e-27 95.0 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBZ14487.1 - 0.014 14.4 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 CBZ14487.1 - 0.092 11.5 0.1 0.32 9.7 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Kinase-like PF14531.6 CBZ14487.1 - 0.12 11.6 0.0 0.4 10.0 0.0 1.7 2 0 0 2 2 2 0 Kinase-like BUD22 PF09073.10 CBZ14487.1 - 0.13 11.6 24.5 0.26 10.6 24.5 1.4 1 0 0 1 1 1 0 BUD22 ABC1 PF03109.16 CBZ14487.1 - 0.16 12.1 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 ABC1 family YL1 PF05764.13 CBZ14487.1 - 0.17 12.0 13.2 0.32 11.1 13.2 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 CBZ14487.1 - 0.19 9.9 20.1 0.28 9.4 20.1 1.1 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 CBZ14487.1 - 3 6.5 5.3 4.4 6.0 5.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Apt1 PF10351.9 CBZ14487.1 - 4.4 6.1 10.2 8.3 5.1 10.2 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain TFIIF_alpha PF05793.12 CBZ14487.1 - 7.6 5.0 23.9 15 4.0 23.9 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RRM_1 PF00076.22 CBZ14490.1 - 1.1e-11 44.4 0.0 1.8e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IATP PF04568.12 CBZ14490.1 - 0.093 13.2 2.8 0.15 12.5 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP UDPGP PF01704.18 CBZ14491.1 - 5.5e-116 387.6 0.0 1.3e-115 386.3 0.0 1.5 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase ERCC3_RAD25_C PF16203.5 CBZ14491.1 - 0.15 11.2 0.1 0.38 9.9 0.0 1.6 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase Hydantoinase_B PF02538.14 CBZ14492.1 - 7.5e-197 654.8 0.8 1.1e-196 654.3 0.8 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 CBZ14492.1 - 3.4e-93 312.1 0.6 3.4e-93 312.1 0.6 2.0 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 CBZ14492.1 - 8.1e-53 178.8 0.5 3.3e-51 173.5 0.1 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Nkap_C PF06047.11 CBZ14492.1 - 0.0038 17.3 0.0 0.0091 16.1 0.0 1.5 1 0 0 1 1 1 1 NF-kappa-B-activating protein C-terminal domain Kinesin PF00225.23 CBZ14493.1 - 3.5e-48 164.2 0.1 3.5e-48 164.2 0.1 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ14493.1 - 1.5e-14 54.2 0.0 4.5e-14 52.6 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 CBZ14493.1 - 0.038 14.4 0.0 0.038 14.4 0.0 3.4 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 CBZ14493.1 - 0.054 13.8 1.4 0.15 12.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CBZ14493.1 - 0.066 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 CBZ14493.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ACP_syn_III_C PF08541.10 CBZ14493.1 - 0.13 12.4 0.2 15 5.9 0.0 3.3 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal AAA_23 PF13476.6 CBZ14493.1 - 0.46 10.9 6.5 12 6.3 0.5 3.2 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 CBZ14493.1 - 1.8 8.6 0.0 1.8 8.6 0.0 2.8 4 0 0 4 4 4 0 Helicase HerA, central domain BLOC1_2 PF10046.9 CBZ14493.1 - 1.9 8.8 10.2 0.83 10.0 1.5 3.5 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FAM76 PF16046.5 CBZ14493.1 - 2 7.7 11.4 0.49 9.7 1.3 2.9 2 1 0 2 2 2 0 FAM76 protein CENP-F_leu_zip PF10473.9 CBZ14502.1 - 3.7e-54 182.6 771.1 0.00063 19.8 16.7 36.7 4 1 42 46 46 46 39 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERM PF00769.19 CBZ14502.1 - 5.5e-45 154.1 1033.6 6.3e-06 26.2 36.2 29.8 5 3 24 30 30 29 25 Ezrin/radixin/moesin family KASH_CCD PF14662.6 CBZ14502.1 - 1.2e-30 106.8 707.7 0.0076 16.1 27.6 28.1 4 2 26 30 30 29 23 Coiled-coil region of CCDC155 or KASH GAS PF13851.6 CBZ14502.1 - 3.4e-28 98.4 701.4 0.019 14.3 22.7 40.0 5 2 40 45 45 45 36 Growth-arrest specific micro-tubule binding Taxilin PF09728.9 CBZ14502.1 - 1.2e-27 96.9 569.7 0.0024 17.1 24.6 31.6 4 1 23 28 28 28 22 Myosin-like coiled-coil protein DUF2353 PF09789.9 CBZ14502.1 - 4e-18 65.9 531.6 6.2e-05 22.5 22.1 21.6 2 2 17 22 22 22 15 Uncharacterized coiled-coil protein (DUF2353) ADIP PF11559.8 CBZ14502.1 - 2.3e-14 53.8 639.4 0.014 15.5 6.7 41.6 4 2 46 50 50 49 25 Afadin- and alpha -actinin-Binding Laminin_I PF06008.14 CBZ14502.1 - 1.2e-13 51.4 605.8 3.9e-05 23.5 17.0 27.9 3 2 20 27 27 26 16 Laminin Domain I Fez1 PF06818.15 CBZ14502.1 - 3.8e-09 37.3 667.6 0.025 15.1 26.7 25.5 2 2 25 28 28 27 17 Fez1 Nup88 PF10168.9 CBZ14502.1 - 1.5e-05 23.1 522.8 0.017 12.9 9.6 31.2 3 1 30 33 33 33 26 Nuclear pore component UPF0242 PF06785.11 CBZ14502.1 - 0.00015 21.9 8.2 0.00015 21.9 8.2 40.4 3 2 25 28 28 16 1 Uncharacterised protein family (UPF0242) N-terminus PRKG1_interact PF15898.5 CBZ14502.1 - 0.0002 22.2 674.5 0.005 17.7 12.8 41.0 5 2 37 42 42 38 13 cGMP-dependent protein kinase interacting domain TPR_MLP1_2 PF07926.12 CBZ14502.1 - 0.00094 19.2 850.5 0.042 13.9 20.9 34.4 10 5 28 40 40 40 19 TPR/MLP1/MLP2-like protein FTA4 PF13093.6 CBZ14502.1 - 0.036 14.0 0.2 0.036 14.0 0.2 25.9 5 2 9 14 14 6 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Img2 PF05046.14 CBZ14502.1 - 0.096 13.0 33.4 29 5.0 0.1 15.3 10 3 1 12 12 11 0 Mitochondrial large subunit ribosomal protein (Img2) Syntaxin_2 PF14523.6 CBZ14502.1 - 0.93 9.9 250.8 1.6 9.2 1.6 32.1 4 1 39 44 44 43 0 Syntaxin-like protein DUF167 PF02594.16 CBZ14505.1 - 1.4e-12 47.6 0.1 1.9e-08 34.3 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised ACR, YggU family COG1872 Nup188 PF10487.9 CBZ14507.1 - 0.00078 17.5 0.0 0.0013 16.8 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 PLDc_2 PF13091.6 CBZ14508.1 - 1.2e-30 106.1 0.0 1.7e-23 82.9 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 CBZ14508.1 - 1.4e-05 25.0 0.6 0.016 15.4 0.2 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif DUF2046 PF09755.9 CBZ14509.1 - 3.3e-06 26.6 26.4 5.4e-06 25.8 22.6 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) TMPIT PF07851.13 CBZ14509.1 - 0.00076 18.8 15.4 0.035 13.4 6.1 2.3 2 0 0 2 2 2 2 TMPIT-like protein MscS_porin PF12795.7 CBZ14509.1 - 0.0065 16.1 22.4 0.17 11.4 13.3 2.2 2 0 0 2 2 2 2 Mechanosensitive ion channel porin domain ATG16 PF08614.11 CBZ14509.1 - 0.016 15.4 5.9 0.016 15.4 5.9 3.2 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Exonuc_VII_L PF02601.15 CBZ14509.1 - 0.034 13.7 13.7 0.23 11.0 7.4 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit Il2rg PF15874.5 CBZ14509.1 - 0.57 10.5 4.6 0.77 10.1 0.5 2.8 2 2 1 3 3 3 0 Putative Interleukin 2 receptor, gamma chain Myosin_tail_1 PF01576.19 CBZ14509.1 - 0.58 7.9 30.4 0.4 8.4 18.5 2.0 2 0 0 2 2 2 0 Myosin tail Atg14 PF10186.9 CBZ14509.1 - 0.86 8.6 19.7 2.3 7.2 12.4 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Prominin PF05478.11 CBZ14509.1 - 4 5.3 10.9 0.41 8.5 5.6 1.7 2 0 0 2 2 2 0 Prominin Kelch_6 PF13964.6 CBZ14517.1 - 2.8e-26 90.9 7.3 4.7e-07 29.9 0.1 5.9 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 CBZ14517.1 - 2e-20 72.5 10.8 0.00014 22.1 0.0 7.1 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_1 PF01344.25 CBZ14517.1 - 4.6e-20 70.9 21.0 1.1e-05 24.9 0.4 6.2 7 0 0 7 7 7 5 Kelch motif Kelch_5 PF13854.6 CBZ14517.1 - 2.5e-19 68.8 11.1 3.4e-06 26.9 0.0 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 CBZ14517.1 - 2.7e-17 62.5 2.3 7.3e-06 25.9 0.0 5.7 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 CBZ14517.1 - 1.8e-13 49.8 17.2 0.0009 19.1 0.2 6.8 6 1 0 6 6 6 5 Kelch motif DUF4111 PF13427.6 CBZ14519.1 - 0.028 14.6 0.0 0.088 13.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) HTH_26 PF13443.6 CBZ14519.1 - 0.12 12.8 0.2 19 5.8 0.1 3.0 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain PilX_N PF14341.6 CBZ14521.1 - 0.17 11.8 0.5 0.43 10.6 0.5 1.7 1 0 0 1 1 1 0 PilX N-terminal DS PF01916.17 CBZ14522.1 - 2.7e-86 289.4 0.0 3.2e-86 289.1 0.0 1.1 1 0 0 1 1 1 1 Deoxyhypusine synthase AAA_5 PF07728.14 CBZ14523.1 - 7.8e-89 294.8 0.0 4.1e-22 78.7 0.0 7.0 5 1 1 6 6 6 5 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 CBZ14523.1 - 2.3e-33 114.6 3.7 1.9e-13 50.5 0.1 4.4 3 0 0 3 3 3 3 Midasin AAA lid domain AAA_lid_5 PF17865.1 CBZ14523.1 - 6.1e-22 77.7 0.0 3.5e-21 75.3 0.0 2.3 2 0 0 2 2 2 1 Midasin AAA lid domain AAA_3 PF07726.11 CBZ14523.1 - 1.8e-18 66.6 0.0 0.0041 17.0 0.0 6.1 6 0 0 6 6 6 3 ATPase family associated with various cellular activities (AAA) AAA_6 PF12774.7 CBZ14523.1 - 3.3e-14 52.6 0.4 0.0016 17.5 0.0 6.4 6 1 0 6 6 6 3 Hydrolytic ATP binding site of dynein motor region AAA PF00004.29 CBZ14523.1 - 4.1e-14 53.1 1.3 0.00076 19.9 0.0 5.2 4 1 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CBZ14523.1 - 1.3e-13 50.9 0.0 0.0026 17.3 0.0 4.5 4 0 0 4 4 4 4 P-loop containing dynein motor region Dynein_heavy PF03028.15 CBZ14523.1 - 1.6e-12 47.5 0.0 0.03 14.4 0.0 4.1 3 0 0 3 3 3 3 Dynein heavy chain region D6 P-loop domain AAA_22 PF13401.6 CBZ14523.1 - 5.5e-12 46.1 0.0 0.019 15.3 0.0 5.5 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 CBZ14523.1 - 3.4e-11 43.8 13.1 0.022 15.1 0.1 7.8 7 1 0 7 7 5 3 AAA ATPase domain TsaE PF02367.17 CBZ14523.1 - 1e-06 28.8 0.6 1.4 8.9 0.0 4.5 4 0 0 4 4 4 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 CBZ14523.1 - 2.1e-06 27.6 0.0 1.5 8.5 0.0 4.5 4 0 0 4 4 4 1 Sigma-54 interaction domain AAA_14 PF13173.6 CBZ14523.1 - 2.7e-06 27.4 0.0 0.022 14.8 0.0 4.2 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.6 CBZ14523.1 - 1.1e-05 25.9 0.0 1.1 9.8 0.0 5.1 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.6 CBZ14523.1 - 1.5e-05 24.6 0.9 12 5.7 0.0 4.7 4 0 0 4 4 4 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 CBZ14523.1 - 5e-05 23.1 0.0 0.14 11.9 0.0 3.3 3 0 0 3 3 3 2 IstB-like ATP binding protein T2SSE PF00437.20 CBZ14523.1 - 5.5e-05 22.3 0.0 0.45 9.5 0.0 4.2 4 0 0 4 4 4 1 Type II/IV secretion system protein Mg_chelatase PF01078.21 CBZ14523.1 - 7.7e-05 22.2 0.7 18 4.6 0.0 6.0 7 0 0 7 7 7 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 CBZ14523.1 - 0.00013 22.1 4.6 5.3 7.2 0.0 5.3 5 0 0 5 5 4 1 AAA domain Sigma54_activ_2 PF14532.6 CBZ14523.1 - 0.00014 22.0 0.0 0.82 9.8 0.0 4.2 4 0 0 4 4 4 1 Sigma-54 interaction domain RsgA_GTPase PF03193.16 CBZ14523.1 - 0.00031 20.7 0.1 2.2 8.2 0.0 3.7 3 0 0 3 3 3 1 RsgA GTPase AAA_25 PF13481.6 CBZ14523.1 - 0.00041 20.0 5.0 0.89 9.1 0.0 5.0 5 0 0 5 5 5 1 AAA domain Rad17 PF03215.15 CBZ14523.1 - 0.0013 18.7 0.5 9.4 6.1 0.0 4.3 4 0 0 4 4 4 0 Rad17 P-loop domain CPT PF07931.12 CBZ14523.1 - 0.0017 18.2 0.2 1.1 9.0 0.0 4.0 3 0 0 3 3 3 1 Chloramphenicol phosphotransferase-like protein AAA_8 PF12780.7 CBZ14523.1 - 0.0023 17.3 0.0 5.5 6.2 0.0 3.7 4 0 0 4 4 3 1 P-loop containing dynein motor region D4 DUF815 PF05673.13 CBZ14523.1 - 0.0064 15.7 1.2 2.8 7.0 0.1 3.2 4 0 0 4 4 4 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 CBZ14523.1 - 0.016 15.0 0.2 6.2 6.5 0.0 4.1 5 0 0 5 5 5 0 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 CBZ14523.1 - 0.024 15.0 2.1 12 6.2 0.1 3.9 3 0 0 3 3 3 0 AAA domain MeaB PF03308.16 CBZ14523.1 - 0.032 13.2 1.1 0.59 9.1 0.1 3.1 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 CBZ14523.1 - 0.04 14.3 0.4 47 4.4 0.0 4.2 4 0 0 4 4 4 0 RNA helicase ABC_tran PF00005.27 CBZ14523.1 - 0.051 14.1 15.7 1.4 9.5 0.1 5.3 5 0 0 5 5 4 0 ABC transporter AAA_5 PF07728.14 CBZ14524.1 - 2e-24 86.2 0.0 3.5e-14 53.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBZ14524.1 - 4.3e-11 43.5 0.6 4.2e-05 24.0 0.0 2.6 3 0 0 3 3 2 2 AAA ATPase domain AAA_7 PF12775.7 CBZ14524.1 - 2.5e-10 40.2 0.2 3.9e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 P-loop containing dynein motor region Sigma54_activat PF00158.26 CBZ14524.1 - 8.4e-10 38.6 0.0 0.00072 19.3 0.0 2.2 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_lid_7 PF17867.1 CBZ14524.1 - 1.4e-09 38.1 0.0 7.7e-09 35.7 0.0 2.1 1 1 0 1 1 1 1 Midasin AAA lid domain AAA_6 PF12774.7 CBZ14524.1 - 1e-08 34.5 0.1 0.0027 16.7 0.0 2.2 2 0 0 2 2 2 2 Hydrolytic ATP binding site of dynein motor region AAA_22 PF13401.6 CBZ14524.1 - 4.6e-08 33.4 0.1 0.0019 18.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 CBZ14524.1 - 3.6e-07 30.2 0.2 0.00087 19.3 0.1 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 CBZ14524.1 - 4.2e-07 30.2 0.0 9.5e-05 22.5 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain ABC_tran PF00005.27 CBZ14524.1 - 1.1e-06 29.3 0.0 0.016 15.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA PF00004.29 CBZ14524.1 - 1.6e-06 28.6 0.0 0.0079 16.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 CBZ14524.1 - 7e-06 25.9 0.0 0.0092 15.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CBZ14524.1 - 7e-06 26.1 0.0 0.038 14.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 CBZ14524.1 - 9.5e-06 25.6 0.1 0.071 13.0 0.0 2.7 3 0 0 3 3 2 2 NACHT domain Zeta_toxin PF06414.12 CBZ14524.1 - 1.7e-05 24.2 0.0 0.042 13.1 0.0 2.5 2 1 0 2 2 2 2 Zeta toxin RNA_helicase PF00910.22 CBZ14524.1 - 1.8e-05 25.1 0.0 0.019 15.3 0.0 2.5 2 0 0 2 2 2 1 RNA helicase DUF815 PF05673.13 CBZ14524.1 - 4.3e-05 22.8 0.1 0.011 14.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Rad17 PF03215.15 CBZ14524.1 - 5.7e-05 23.1 0.0 0.46 10.4 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_11 PF13086.6 CBZ14524.1 - 0.00012 22.0 0.0 0.075 12.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CBZ14524.1 - 0.00028 20.8 0.1 0.08 12.8 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase DAP3 PF10236.9 CBZ14524.1 - 0.00033 19.9 0.1 0.2 10.8 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial ribosomal death-associated protein 3 T2SSE PF00437.20 CBZ14524.1 - 0.00039 19.6 0.3 0.018 14.1 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 CBZ14524.1 - 0.00064 19.3 0.1 0.59 9.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 CBZ14524.1 - 0.00077 19.2 0.0 1.6 8.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 CBZ14524.1 - 0.00086 19.9 0.1 0.18 12.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CBZ14524.1 - 0.0021 17.8 0.0 0.054 13.2 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_30 PF13604.6 CBZ14524.1 - 0.0024 17.6 0.0 0.69 9.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 CBZ14524.1 - 0.003 17.3 0.1 0.53 10.0 0.0 3.1 4 0 0 4 4 3 1 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 CBZ14524.1 - 0.0032 17.5 0.1 0.64 10.0 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ATPase PF06745.13 CBZ14524.1 - 0.0038 16.6 0.0 1.5 8.1 0.0 2.2 2 0 0 2 2 2 1 KaiC DUF2791 PF10923.8 CBZ14524.1 - 0.0071 15.2 0.0 2.7 6.7 0.0 2.2 2 0 0 2 2 2 1 P-loop Domain of unknown function (DUF2791) ATPase_2 PF01637.18 CBZ14524.1 - 0.0086 16.0 0.0 0.35 10.7 0.0 2.2 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea DEAD PF00270.29 CBZ14524.1 - 0.011 15.4 0.0 4.6 7.0 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase NTPase_1 PF03266.15 CBZ14524.1 - 0.012 15.6 0.4 0.3 11.0 0.1 2.3 2 0 0 2 2 2 0 NTPase dNK PF01712.19 CBZ14524.1 - 0.012 15.5 0.1 3.6 7.4 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase TniB PF05621.11 CBZ14524.1 - 0.015 14.7 0.0 0.37 10.2 0.0 2.7 3 0 0 3 3 3 0 Bacterial TniB protein PhoH PF02562.16 CBZ14524.1 - 0.022 14.2 0.2 0.61 9.5 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein SRP54 PF00448.22 CBZ14524.1 - 0.037 13.6 0.1 8.2 6.0 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_19 PF13245.6 CBZ14524.1 - 0.053 13.9 0.3 1.7 8.9 0.0 2.5 2 1 0 2 2 2 0 AAA domain DUF853 PF05872.12 CBZ14524.1 - 0.059 12.0 0.3 0.88 8.1 0.1 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) Mg_chelatase PF01078.21 CBZ14524.1 - 0.073 12.5 0.0 1.6 8.1 0.0 2.4 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 CBZ14524.1 - 0.074 13.2 0.0 4.5 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 CBZ14524.1 - 0.087 11.9 0.0 4.1 6.4 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_2 PF07724.14 CBZ14524.1 - 0.091 12.9 0.1 15 5.6 0.0 2.5 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) DnaB_C PF03796.15 CBZ14524.1 - 0.091 12.1 0.1 4.7 6.5 0.0 2.5 3 0 0 3 3 3 0 DnaB-like helicase C terminal domain DNA_pol3_delta2 PF13177.6 CBZ14524.1 - 0.12 12.1 0.1 8 6.2 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase III, delta subunit TIP49 PF06068.13 CBZ14524.1 - 0.14 11.3 0.0 14 4.8 0.0 2.1 2 0 0 2 2 2 0 TIP49 P-loop domain Roc PF08477.13 CBZ14524.1 - 0.15 12.3 0.4 4.6 7.5 0.0 2.9 4 0 0 4 4 2 0 Ras of Complex, Roc, domain of DAPkinase Hpr_kinase_C PF07475.12 CBZ14524.1 - 0.15 11.6 0.0 13 5.2 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_23 PF13476.6 CBZ14524.1 - 0.17 12.3 0.0 9.1 6.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Enkurin PF13864.6 CBZ14526.1 - 5.9e-19 68.3 6.4 1.1e-18 67.5 6.4 1.5 1 0 0 1 1 1 1 Calmodulin-binding Seryl_tRNA_N PF02403.22 CBZ14526.1 - 4.9 7.4 7.3 2.7 8.3 1.4 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain BCDHK_Adom3 PF10436.9 CBZ14527.1 - 4e-18 65.8 0.1 6.6e-18 65.1 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CBZ14527.1 - 2.1e-10 41.1 0.0 5.1e-09 36.6 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CBZ14527.1 - 3.8e-05 23.5 0.0 8.2e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ZZ PF00569.17 CBZ14528.1 - 4.6e-07 29.5 7.5 4.6e-07 29.5 7.5 3.0 2 0 0 2 2 2 1 Zinc finger, ZZ type C1_1 PF00130.22 CBZ14528.1 - 0.85 9.6 16.5 1.9 8.4 3.1 3.1 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) LRR_6 PF13516.6 CBZ14529.1 - 5.8e-05 22.8 2.0 0.23 11.6 0.0 4.1 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.7 CBZ14529.1 - 0.0088 16.4 1.3 6.5 7.3 0.0 3.7 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_4 PF12799.7 CBZ14531.1 - 7.7e-13 48.4 20.3 5.3e-05 23.5 2.5 5.7 4 2 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ14531.1 - 2.1e-11 43.4 15.5 5.2e-06 26.1 1.3 3.9 2 2 2 4 4 4 4 Leucine rich repeat LRR_1 PF00560.33 CBZ14531.1 - 1.1e-05 25.3 14.3 1.4 9.7 0.6 7.2 6 1 1 7 7 7 2 Leucine Rich Repeat LRR_6 PF13516.6 CBZ14531.1 - 0.00059 19.7 19.0 0.12 12.5 0.8 7.1 7 0 0 7 7 7 1 Leucine Rich repeat LRR_9 PF14580.6 CBZ14531.1 - 0.091 12.3 2.4 3 7.3 0.1 3.0 2 1 1 3 3 3 0 Leucine-rich repeat DUF3729 PF12526.8 CBZ14531.1 - 0.46 12.1 5.9 2.1 9.9 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3729) Acetyltransf_13 PF13880.6 CBZ14534.1 - 2.2e-22 78.8 0.0 5e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_7 PF13508.7 CBZ14534.1 - 0.026 15.0 0.0 0.087 13.3 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 CBZ14535.1 - 1.2e-06 27.8 13.5 1.6e-06 27.3 13.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ATPase_gene1 PF09527.10 CBZ14535.1 - 1.9 8.7 5.0 0.4 10.9 0.8 2.1 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter DUF2946 PF11162.8 CBZ14537.1 - 1.3e-12 48.4 0.0 2.4e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2946) DUF4692 PF15763.5 CBZ14537.1 - 0.024 15.1 0.0 0.043 14.3 0.0 1.4 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) EphA2_TM PF14575.6 CBZ14537.1 - 0.073 14.0 0.1 0.16 12.8 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ECSCR PF15820.5 CBZ14537.1 - 0.19 11.6 0.3 0.34 10.8 0.3 1.3 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator PRIMA1 PF16101.5 CBZ14537.1 - 0.24 11.4 0.5 0.45 10.6 0.5 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF4006 PF13179.6 CBZ14537.1 - 6.4 6.8 5.5 23 5.0 0.5 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF4006) Metallophos PF00149.28 CBZ14538.1 - 0.007 16.9 0.1 0.031 14.8 0.1 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.28 CBZ14539.1 - 0.0047 17.4 0.1 0.022 15.3 0.1 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase NUDIX PF00293.28 CBZ14540.1 - 0.0015 18.6 0.1 8.6 6.4 0.2 3.6 3 1 0 3 3 3 2 NUDIX domain Rad1 PF02144.16 CBZ14541.1 - 6.7e-07 28.7 0.0 1.9e-06 27.2 0.0 1.6 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Gp-FAR-1 PF05823.12 CBZ14543.1 - 0.0012 19.2 8.7 0.0012 19.2 8.7 3.2 1 1 2 3 3 3 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Methyltransf_8 PF05148.15 CBZ14544.1 - 1.7e-53 181.7 0.0 2.3e-53 181.3 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 CBZ14544.1 - 6.1e-07 30.0 0.1 1.1e-05 26.0 0.1 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ14544.1 - 5.8e-05 23.7 0.0 0.024 15.3 0.0 2.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBZ14544.1 - 0.0012 18.2 0.0 0.0033 16.8 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family IHABP4_N PF16174.5 CBZ14544.1 - 0.43 11.2 8.8 0.73 10.4 8.8 1.3 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal DAO PF01266.24 CBZ14545.1 - 2.2e-18 67.0 0.1 7.4e-16 58.7 0.1 3.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 CBZ14545.1 - 5e-11 42.6 0.1 2.1e-10 40.6 0.1 2.1 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_oxidored PF12831.7 CBZ14545.1 - 6e-08 32.5 0.1 9.5e-08 31.8 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CBZ14545.1 - 6.5e-07 28.8 0.1 1.2e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 CBZ14545.1 - 8.5e-06 25.9 0.4 2.3e-05 24.5 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 CBZ14545.1 - 1.5e-05 24.3 0.0 3.1e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 CBZ14545.1 - 0.00036 19.3 0.3 0.00057 18.7 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 CBZ14545.1 - 0.00076 18.8 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CBZ14545.1 - 0.068 12.2 0.3 0.15 11.1 0.3 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 CBZ14545.1 - 0.16 12.6 0.6 0.46 11.1 0.3 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GGACT PF06094.12 CBZ14546.1 - 5e-09 36.8 0.2 5.2e-06 27.1 0.2 3.1 2 2 0 2 2 2 2 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 CBZ14546.1 - 4.9e-07 30.1 1.0 3.1e-06 27.5 0.1 2.7 3 0 0 3 3 3 1 AIG2-like family Tubulin PF00091.25 CBZ14548.1 - 1.7e-27 96.9 0.2 2.6e-14 53.9 0.0 2.9 1 1 1 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 CBZ14548.1 - 0.0045 16.2 0.0 0.0067 15.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin like PPR_2 PF13041.6 CBZ14549.1 - 3e-10 40.1 0.1 0.029 14.5 0.0 4.7 3 1 2 5 5 5 3 PPR repeat family PPR PF01535.20 CBZ14549.1 - 8.3e-08 32.0 0.0 1.7 9.0 0.0 4.2 4 0 0 4 4 4 3 PPR repeat PPR_3 PF13812.6 CBZ14549.1 - 0.0011 19.1 0.0 0.011 15.8 0.0 2.5 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR_long PF17177.4 CBZ14549.1 - 0.0016 17.8 0.3 0.015 14.7 0.0 2.1 1 1 1 2 2 2 1 Pentacotripeptide-repeat region of PRORP DNA_RNApol_7kD PF03604.13 CBZ14550.1 - 0.048 13.3 1.2 0.094 12.4 1.2 1.6 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit TF_Zn_Ribbon PF08271.12 CBZ14550.1 - 0.062 12.8 0.8 0.84 9.2 0.1 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding PhnA_Zn_Ribbon PF08274.12 CBZ14550.1 - 0.1 12.6 0.6 6.3 6.8 0.0 2.2 2 0 0 2 2 2 0 PhnA Zinc-Ribbon CTP_transf_like PF01467.26 CBZ14551.1 - 7.8e-06 26.1 0.0 3.4e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 Cytidylyltransferase-like Ribosomal_S15 PF00312.22 CBZ14552.1 - 3e-07 30.6 1.6 6.3e-07 29.5 1.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S15 DUF4404 PF14357.6 CBZ14552.1 - 0.033 14.8 0.9 0.61 10.8 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) MORN PF02493.20 CBZ14553.1 - 1.8e-16 58.9 17.9 4.8e-05 23.0 0.1 7.4 9 0 0 9 9 9 4 MORN repeat WW PF00397.26 CBZ14553.1 - 0.098 12.8 0.3 0.24 11.5 0.3 1.7 1 0 0 1 1 1 0 WW domain RWD PF05773.22 CBZ14555.1 - 4.5e-09 36.6 0.6 7.4e-09 35.9 0.6 1.4 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 CBZ14555.1 - 0.00019 21.9 0.6 0.00038 20.9 0.6 1.5 1 0 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 phage_tail_N PF08400.10 CBZ14555.1 - 0.081 12.9 0.7 0.83 9.6 0.1 2.2 1 1 0 2 2 2 0 Prophage tail fibre N-terminal DnaJ_C PF01556.18 CBZ14556.1 - 1.2e-17 64.3 0.0 1.9e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 CBZ14556.1 - 1.6e-09 38.0 10.5 3.3e-09 37.0 10.5 1.6 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CBZ14556.1 - 0.0004 20.3 10.3 0.06 13.3 2.5 2.9 2 1 1 3 3 3 2 Tryptophan RNA-binding attenuator protein inhibitory protein Rhv PF00073.20 CBZ14556.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 picornavirus capsid protein CTP_synth_N PF06418.14 CBZ14557.1 - 2.7e-106 354.7 0.0 3.5e-106 354.4 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 CBZ14557.1 - 1.8e-45 155.1 0.0 7.1e-45 153.1 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CBZ14557.1 - 2.8e-08 33.8 0.1 2.3e-07 30.8 0.0 2.1 2 0 0 2 2 2 1 Peptidase C26 CbiA PF01656.23 CBZ14557.1 - 0.012 15.7 0.0 0.03 14.4 0.0 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 CBZ14557.1 - 0.19 10.6 0.0 0.33 9.9 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CobA_CobO_BtuR PF02572.15 CBZ14557.1 - 0.21 11.8 0.4 0.67 10.2 0.2 1.8 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP MORN PF02493.20 CBZ14559.1 - 1.5e-18 65.5 40.4 0.00059 19.6 1.2 6.8 7 0 0 7 7 7 6 MORN repeat Kinesin PF00225.23 CBZ14564.1 - 4.5e-81 272.4 0.2 3.2e-74 249.8 0.0 3.1 3 0 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 CBZ14564.1 - 7e-10 39.0 0.6 0.00038 20.4 0.0 3.0 3 0 0 3 3 3 2 Microtubule binding CLZ PF16526.5 CBZ14564.1 - 0.04 14.3 0.4 0.04 14.3 0.4 3.7 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fib_alpha PF08702.10 CBZ14564.1 - 0.33 11.1 13.4 4.6 7.4 4.1 3.8 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Gon7 PF08738.10 CBZ14564.1 - 0.63 10.1 9.8 0.11 12.6 0.3 3.9 4 0 0 4 4 4 0 Gon7 family BRE1 PF08647.11 CBZ14564.1 - 1.3 9.1 8.7 15 5.8 0.3 4.0 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase Cep57_CLD_2 PF14197.6 CBZ14564.1 - 7.4 6.7 23.8 2.7 8.1 1.8 5.0 4 0 0 4 4 4 0 Centrosome localisation domain of PPC89 TPR_14 PF13428.6 CBZ14565.1 - 1.2e-06 28.8 9.1 2.5 9.1 0.2 6.0 3 1 3 6 6 6 3 Tetratricopeptide repeat Suf PF05843.14 CBZ14565.1 - 0.002 18.1 4.2 0.18 11.8 0.1 3.3 3 1 0 3 3 3 2 Suppressor of forked protein (Suf) NRDE-2 PF08424.10 CBZ14565.1 - 0.03 13.4 0.1 0.66 9.1 0.1 2.2 2 0 0 2 2 2 0 NRDE-2, necessary for RNA interference TPR_1 PF00515.28 CBZ14565.1 - 0.056 13.3 0.3 2.6 8.0 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ14565.1 - 0.058 13.5 5.9 20 5.6 0.2 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ14565.1 - 0.23 11.7 0.4 49 4.5 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat HEAT PF02985.22 CBZ14566.1 - 6.7e-29 97.5 42.7 0.00047 20.2 0.2 13.8 15 0 0 15 15 15 9 HEAT repeat HEAT_2 PF13646.6 CBZ14566.1 - 1.9e-27 95.4 23.3 9.9e-09 35.5 0.4 8.2 3 3 5 8 8 8 8 HEAT repeats Cnd1 PF12717.7 CBZ14566.1 - 1.3e-08 35.0 8.9 0.0065 16.5 0.1 5.1 2 1 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CBZ14566.1 - 2.3e-08 34.5 0.1 0.0013 19.2 0.0 5.7 2 1 2 6 6 6 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 CBZ14566.1 - 5.2e-08 33.2 28.7 9.6e-05 22.8 0.2 8.3 8 4 3 11 11 11 2 HEAT-like repeat Adaptin_N PF01602.20 CBZ14566.1 - 9.8e-06 24.4 4.2 0.0016 17.1 2.4 3.0 2 1 1 3 3 3 2 Adaptin N terminal region CLASP_N PF12348.8 CBZ14566.1 - 0.0011 18.6 1.3 1.5 8.3 0.1 4.1 1 1 3 4 4 4 2 CLASP N terminal Arm PF00514.23 CBZ14566.1 - 0.71 10.0 5.4 44 4.3 0.0 4.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 CBZ14566.1 - 0.86 10.5 3.2 6.5 7.7 0.0 4.3 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Tfb2 PF03849.14 CBZ14567.1 - 0.0066 15.5 1.3 0.0088 15.0 1.3 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Acyl-CoA_dh_C PF12806.7 CBZ14567.1 - 0.029 14.5 0.1 0.047 13.8 0.1 1.3 1 0 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like Cas_Csy4 PF09618.10 CBZ14567.1 - 0.077 13.1 2.0 0.15 12.2 2.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) DUF775 PF05603.12 CBZ14568.1 - 3.7e-21 75.6 0.0 5.5e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Cupin_3 PF05899.12 CBZ14568.1 - 0.12 12.0 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Pkinase PF00069.25 CBZ14572.1 - 4.2e-55 186.9 0.0 6.9e-55 186.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ14572.1 - 1.5e-35 122.7 0.0 2.4e-35 122.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 CBZ14572.1 - 3.5e-17 62.3 0.4 9.1e-08 32.1 0.1 4.3 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain PAS PF00989.25 CBZ14572.1 - 5.7e-06 26.3 0.0 1.9e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 CBZ14572.1 - 4.5e-05 23.7 0.0 0.0001 22.5 0.0 1.6 1 0 0 1 1 1 1 PAS domain Kinase-like PF14531.6 CBZ14572.1 - 0.00066 19.1 0.0 0.0053 16.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like PAS_4 PF08448.10 CBZ14572.1 - 0.0058 16.9 0.0 0.028 14.6 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 CBZ14572.1 - 0.017 15.4 0.0 0.038 14.3 0.0 1.6 1 0 0 1 1 1 0 PAS fold Tombus_movement PF05318.12 CBZ14572.1 - 0.59 11.0 3.2 1.2 10.0 0.8 3.0 2 0 0 2 2 2 0 Tombusvirus movement protein Tubulin_3 PF14881.6 CBZ14573.1 - 8.4e-05 22.3 0.0 0.00017 21.3 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 CBZ14573.1 - 0.0059 16.9 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain TTL PF03133.15 CBZ14574.1 - 3.9e-44 150.9 0.0 5e-42 144.0 0.0 2.2 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family Snf7 PF03357.21 CBZ14575.1 - 0.028 14.0 1.5 0.028 14.0 1.5 4.3 2 1 2 4 4 4 0 Snf7 MHB PF16525.5 CBZ14575.1 - 0.63 10.3 12.1 0.66 10.3 0.1 3.9 4 1 0 4 4 4 0 Haemophore, haem-binding DUF4407 PF14362.6 CBZ14575.1 - 6.4 6.0 29.0 0.18 11.1 10.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) AAA PF00004.29 CBZ14576.1 - 5.4e-49 166.0 0.0 1.8e-36 125.5 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBZ14576.1 - 2e-09 37.1 0.0 4.2e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 CBZ14576.1 - 2.8e-08 34.1 0.9 0.062 13.6 0.0 4.5 2 2 2 4 4 4 1 AAA domain AAA_18 PF13238.6 CBZ14576.1 - 1.3e-07 32.3 0.0 0.02 15.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 CBZ14576.1 - 2.2e-07 31.0 0.0 0.0038 17.2 0.0 3.0 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBZ14576.1 - 1e-06 29.2 0.1 0.059 13.8 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain Mg_chelatase PF01078.21 CBZ14576.1 - 9e-06 25.2 0.0 0.0033 16.8 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 CBZ14576.1 - 1.1e-05 24.8 0.0 0.031 13.5 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain RuvB_N PF05496.12 CBZ14576.1 - 0.00017 21.4 0.0 0.077 12.7 0.0 2.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 CBZ14576.1 - 0.0005 20.4 0.0 0.63 10.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 CBZ14576.1 - 0.00054 19.5 0.0 0.0069 15.9 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 CBZ14576.1 - 0.00056 19.7 0.0 0.078 12.7 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_30 PF13604.6 CBZ14576.1 - 0.00077 19.2 0.0 0.8 9.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 CBZ14576.1 - 0.00079 19.6 0.0 0.66 10.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 CBZ14576.1 - 0.0008 19.2 0.0 0.4 10.4 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 CBZ14576.1 - 0.00082 19.2 0.0 0.4 10.5 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 CBZ14576.1 - 0.00085 19.8 0.2 1.3 9.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 CBZ14576.1 - 0.001 19.3 0.0 2 8.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.6 CBZ14576.1 - 0.0012 19.0 0.0 1.2 9.2 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.12 CBZ14576.1 - 0.0012 18.8 0.1 1.1 9.2 0.1 3.7 3 1 0 3 3 3 1 NACHT domain AAA_2 PF07724.14 CBZ14576.1 - 0.0037 17.4 0.0 0.018 15.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.6 CBZ14576.1 - 0.0058 17.0 1.0 1.2 9.5 0.1 3.2 4 0 0 4 4 3 1 AAA domain ABC_tran PF00005.27 CBZ14576.1 - 0.0086 16.6 0.1 0.75 10.3 0.0 3.1 2 1 1 3 3 3 1 ABC transporter TsaE PF02367.17 CBZ14576.1 - 0.0098 15.9 0.0 0.51 10.4 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2075 PF09848.9 CBZ14576.1 - 0.011 15.0 0.8 4.7 6.3 0.0 2.9 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 CBZ14576.1 - 0.011 15.0 0.1 0.63 9.3 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin DUF1599 PF07659.11 CBZ14576.1 - 0.017 15.5 0.1 0.044 14.3 0.1 1.7 1 0 0 1 1 1 0 Nucleotide modification associated domain 1 CDC48_N PF02359.18 CBZ14576.1 - 0.02 15.0 0.0 0.069 13.3 0.0 1.9 1 1 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain AAA_24 PF13479.6 CBZ14576.1 - 0.025 14.3 0.0 0.38 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 CBZ14576.1 - 0.027 14.2 0.0 1 9.0 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase KTI12 PF08433.10 CBZ14576.1 - 0.027 13.9 0.0 9.4 5.6 0.0 2.6 3 0 0 3 3 3 0 Chromatin associated protein KTI12 AAA_11 PF13086.6 CBZ14576.1 - 0.034 14.0 0.0 1.7 8.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 CBZ14576.1 - 0.042 12.9 0.0 6.1 5.8 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein ATPase PF06745.13 CBZ14576.1 - 0.045 13.1 0.1 3.4 6.9 0.1 2.5 2 0 0 2 2 2 0 KaiC ResIII PF04851.15 CBZ14576.1 - 0.051 13.6 0.1 9.9 6.1 0.2 3.2 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit PhoH PF02562.16 CBZ14576.1 - 0.07 12.6 0.0 0.77 9.2 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_29 PF13555.6 CBZ14576.1 - 0.073 12.8 0.5 7.6 6.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.6 CBZ14576.1 - 0.12 11.9 1.1 6 6.4 0.1 3.2 3 0 0 3 3 3 0 AAA domain CPT PF07931.12 CBZ14576.1 - 0.14 12.0 0.0 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein NB-ARC PF00931.22 CBZ14576.1 - 0.16 11.2 0.0 8.1 5.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain MIase PF02426.16 CBZ14577.1 - 0.15 12.3 0.1 0.31 11.2 0.1 1.5 1 0 0 1 1 1 0 Muconolactone delta-isomerase ACPS PF01648.20 CBZ14578.1 - 8.6e-12 45.2 0.0 1.5e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily SCO1-SenC PF02630.14 CBZ14579.1 - 7.7e-29 100.3 0.0 1.1e-26 93.3 0.0 2.3 1 1 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.6 CBZ14579.1 - 0.064 13.6 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like TruD PF01142.18 CBZ14580.1 - 8.4e-11 41.3 0.0 1.8e-06 27.1 0.0 3.3 4 0 0 4 4 4 2 tRNA pseudouridine synthase D (TruD) DUF5407 PF17401.2 CBZ14580.1 - 0.12 12.7 0.7 0.35 11.2 0.7 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5407) DEAD PF00270.29 CBZ14582.1 - 6.6e-29 100.9 0.1 1.1e-15 57.9 0.0 2.6 2 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ14582.1 - 3.8e-16 59.4 0.0 1.3e-15 57.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ14582.1 - 1.1e-06 28.7 0.0 7.3e-06 26.1 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit TniB PF05621.11 CBZ14582.1 - 0.052 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 CBZ14582.1 - 0.062 13.6 1.0 4.8 7.4 0.1 2.7 2 0 0 2 2 2 0 AAA domain Elf1 PF05129.13 CBZ14583.1 - 6.4e-19 67.8 0.4 1e-18 67.1 0.4 1.3 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.6 CBZ14583.1 - 0.1 13.0 0.9 0.47 10.9 0.1 2.2 2 0 0 2 2 2 0 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.10 CBZ14583.1 - 0.13 12.4 0.2 0.29 11.3 0.2 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Elf1 PF05129.13 CBZ14584.1 - 1e-13 51.1 0.1 1.5e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Vps36-NZF-N PF16988.5 CBZ14584.1 - 0.25 10.8 1.3 0.63 9.5 1.3 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Ribonuclease_3 PF00636.26 CBZ14585.1 - 1.8e-05 25.3 0.0 4.7e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease III domain zf-C2H2_11 PF16622.5 CBZ14585.1 - 0.057 13.2 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 zinc-finger C2H2-type AATF-Che1 PF13339.6 CBZ14587.1 - 2.9e-14 53.9 0.3 5.6e-13 49.8 0.0 3.0 3 1 1 4 4 4 1 Apoptosis antagonizing transcription factor TRAUB PF08164.12 CBZ14587.1 - 0.00017 22.0 0.1 0.00017 22.0 0.1 3.0 4 0 0 4 4 4 1 Apoptosis-antagonizing transcription factor, C-terminal EPL1 PF10513.9 CBZ14587.1 - 0.0036 17.7 0.1 0.17 12.2 0.0 2.7 2 0 0 2 2 2 1 Enhancer of polycomb-like APG6_N PF17675.1 CBZ14587.1 - 0.33 11.5 3.5 0.94 10.0 0.0 3.1 3 0 0 3 3 3 0 Apg6 coiled-coil region PBP1_TM PF14812.6 CBZ14589.1 - 2.9 8.3 6.6 0.59 10.5 2.6 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4379 PF14311.6 CBZ14590.1 - 3.6e-16 59.3 6.8 4.8e-10 39.6 3.4 2.6 2 0 0 2 2 2 2 Probable Zinc-ribbon domain HypA PF01155.19 CBZ14590.1 - 0.028 14.4 0.9 0.084 12.9 0.9 1.8 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 CBZ14590.1 - 0.039 14.1 2.9 0.11 12.7 2.9 1.7 1 0 0 1 1 1 0 Zinc ribbon domain Zn_ribbon_SprT PF17283.2 CBZ14590.1 - 6.8 6.7 10.0 19 5.2 10.0 1.8 1 0 0 1 1 1 0 SprT-like zinc ribbon domain zinc_ribbon_4 PF13717.6 CBZ14590.1 - 7.5 6.6 6.5 18 5.3 5.7 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Pkinase PF00069.25 CBZ14591.1 - 2.8e-49 167.8 0.1 2.3e-30 105.9 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ14591.1 - 2.5e-31 108.9 0.0 4.6e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ14591.1 - 2.2e-05 23.4 0.8 0.00018 20.4 0.0 2.4 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CBZ14591.1 - 0.029 13.7 0.0 0.075 12.3 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 CBZ14591.1 - 0.09 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_8 PF13188.7 CBZ14591.1 - 0.11 12.5 0.0 0.39 10.8 0.0 1.9 1 0 0 1 1 1 0 PAS domain ARD PF03079.14 CBZ14592.1 - 4.9e-36 124.3 0.0 7.4e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 ARD/ARD' family DUF953 PF06110.11 CBZ14592.1 - 2.3e-13 49.8 0.0 4e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Cupin_2 PF07883.11 CBZ14592.1 - 3.9e-08 32.9 0.0 6.4e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 CBZ14592.1 - 5.9e-07 29.5 0.0 1.3e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 CBZ14592.1 - 0.051 13.2 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 Cupin DUF4597 PF15366.6 CBZ14594.1 - 0.079 12.7 0.8 0.33 10.7 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) TetR_C_28 PF17937.1 CBZ14594.1 - 0.13 12.7 0.2 0.47 10.9 0.2 1.9 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Glutaredoxin PF00462.24 CBZ14595.1 - 3.5e-11 43.1 0.0 5e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin SH3BGR PF04908.15 CBZ14595.1 - 0.077 13.2 0.0 0.094 12.9 0.0 1.2 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein Thioredoxin_3 PF13192.6 CBZ14595.1 - 0.16 12.0 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain MSP1_C PF07462.11 CBZ14598.1 - 6.1 5.4 7.7 13 4.4 7.7 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Spem1 PF15670.5 CBZ14600.1 - 0.018 14.6 0.5 0.018 14.6 0.5 2.6 2 1 0 2 2 2 0 Spermatid maturation protein 1 Zn_ribbon_17 PF17120.5 CBZ14601.1 - 0.00028 20.4 5.1 0.0011 18.5 5.1 2.0 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 CBZ14601.1 - 0.00038 20.7 3.3 0.0011 19.3 3.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CBZ14601.1 - 0.0063 16.8 8.3 0.016 15.5 8.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CBZ14601.1 - 0.007 16.2 2.3 0.022 14.6 2.3 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ14601.1 - 4.8 7.2 9.9 0.59 10.1 4.9 2.2 2 1 0 2 2 2 0 zinc-RING finger domain AAA PF00004.29 CBZ14602.1 - 0.0075 16.7 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 CBZ14602.1 - 0.017 14.2 0.1 0.043 12.9 0.1 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 CBZ14602.1 - 0.11 12.8 0.0 0.42 10.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CBZ14602.1 - 0.2 11.5 0.0 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MORN PF02493.20 CBZ14603.1 - 8.2e-08 31.7 11.4 0.0074 16.1 0.5 3.9 3 0 0 3 3 3 3 MORN repeat PI3_PI4_kinase PF00454.27 CBZ14605.1 - 2.5e-47 161.8 0.0 5.4e-47 160.7 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 CBZ14605.1 - 4e-31 108.5 4.0 8.1e-31 107.5 4.0 1.6 1 0 0 1 1 1 1 FAT domain FATC PF02260.20 CBZ14605.1 - 2.2e-09 37.0 0.0 5.4e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 FATC domain TFCD_C PF12612.8 CBZ14605.1 - 5.9e-05 23.0 0.3 0.00043 20.2 0.2 2.7 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 CBZ14605.1 - 0.0015 18.6 2.3 42 4.8 0.0 7.1 8 0 0 8 8 8 0 HEAT repeat Ku_PK_bind PF08785.11 CBZ14605.1 - 0.063 13.4 0.6 4.5 7.4 0.0 3.6 4 0 0 4 4 4 0 Ku C terminal domain like TIP120 PF08623.10 CBZ14605.1 - 0.15 11.8 0.6 29 4.4 0.1 3.1 2 1 0 2 2 2 0 TATA-binding protein interacting (TIP20) DnaJ PF00226.31 CBZ14606.1 - 5.1e-18 65.0 2.5 6.2e-18 64.7 0.4 2.3 2 0 0 2 2 2 1 DnaJ domain Myb_DNA-binding PF00249.31 CBZ14606.1 - 9.6e-05 22.5 12.8 0.0007 19.7 0.3 4.4 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CBZ14606.1 - 0.051 13.8 0.9 0.051 13.8 0.9 4.1 4 0 0 4 4 4 0 Myb-like DNA-binding domain YIF1 PF03878.15 CBZ14607.1 - 5.5e-43 147.2 0.9 7.8e-43 146.7 0.9 1.1 1 0 0 1 1 1 1 YIF1 PRP38 PF03371.15 CBZ14608.1 - 3.9e-12 46.4 0.0 6e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 PRP38 family DUF5056 PF16479.5 CBZ14609.1 - 0.33 11.2 1.5 1.6 9.0 0.2 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF5056) YjcB PF15940.5 CBZ14609.1 - 1.9 8.8 8.3 0.86 9.8 4.5 2.4 2 2 0 2 2 2 0 Family of unknown function Esterase PF00756.20 CBZ14610.1 - 0.00027 20.7 0.0 0.0009 19.0 0.0 1.9 1 1 0 1 1 1 1 Putative esterase DUF1935 PF09149.10 CBZ14611.1 - 3.1e-10 40.3 0.0 5.5e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) TIM PF00121.18 CBZ14613.1 - 1.6e-86 289.7 0.2 1.8e-86 289.5 0.2 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Ax_dynein_light PF10211.9 CBZ14614.1 - 1.4e-77 259.9 6.8 1.6e-77 259.7 6.8 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain APG6_N PF17675.1 CBZ14614.1 - 0.00083 19.9 11.4 0.0011 19.6 9.2 1.9 2 0 0 2 2 2 1 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 CBZ14614.1 - 0.021 15.1 11.4 0.075 13.3 7.0 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 bZIP_1 PF00170.21 CBZ14614.1 - 0.022 14.8 4.9 0.074 13.2 1.8 2.3 2 0 0 2 2 2 0 bZIP transcription factor HALZ PF02183.18 CBZ14614.1 - 0.049 13.9 3.0 0.23 11.7 0.7 2.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper Syntaxin-6_N PF09177.11 CBZ14614.1 - 0.075 13.6 5.5 0.15 12.6 5.5 1.6 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Spc24 PF08286.11 CBZ14614.1 - 0.33 11.2 6.0 0.49 10.6 4.3 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 TMF_TATA_bd PF12325.8 CBZ14614.1 - 0.51 10.6 12.8 0.19 12.0 9.9 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Nup88 PF10168.9 CBZ14614.1 - 0.64 7.8 6.9 0.75 7.5 6.9 1.1 1 0 0 1 1 1 0 Nuclear pore component YabA PF06156.13 CBZ14614.1 - 1.4 9.6 6.5 1.4 9.6 5.0 1.7 2 0 0 2 2 2 0 Initiation control protein YabA CENP-H PF05837.12 CBZ14614.1 - 1.7 9.1 10.0 0.32 11.4 6.4 1.6 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Peptidase_C2 PF00648.21 CBZ14615.1 - 6.6e-61 205.9 0.0 9.4e-61 205.4 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 CBZ14615.1 - 6.3e-34 116.5 0.1 1.2e-33 115.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Calpain_III PF01067.22 CBZ14615.1 - 0.003 17.8 0.0 0.02 15.1 0.0 2.2 2 0 0 2 2 2 1 Calpain large subunit, domain III Calpain_III PF01067.22 CBZ14616.1 - 0.001 19.3 0.0 0.0014 18.9 0.0 1.2 1 0 0 1 1 1 1 Calpain large subunit, domain III Peptidase_C2 PF00648.21 CBZ14617.1 - 4.7e-55 186.7 0.0 9.8e-55 185.7 0.0 1.5 2 0 0 2 2 2 1 Calpain family cysteine protease DUF1935 PF09149.10 CBZ14617.1 - 6.7e-33 113.2 0.1 1.3e-32 112.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Tom6 PF17112.5 CBZ14617.1 - 0.1 12.1 0.0 0.29 10.7 0.0 1.8 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom6, fungal Peptidase_C2 PF00648.21 CBZ14618.1 - 4.8e-46 157.1 0.0 7.2e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 CBZ14618.1 - 1.5e-25 89.5 0.0 3.1e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) TetR_C_28 PF17937.1 CBZ14618.1 - 0.086 13.3 0.2 0.19 12.2 0.2 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF1935 PF09149.10 CBZ14619.1 - 0.00024 21.4 0.0 0.00044 20.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.21 CBZ14620.1 - 1e-28 100.3 0.0 1.6e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 CBZ14621.1 - 1.4e-26 92.9 0.0 1.6e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.10 CBZ14622.1 - 2.7e-27 95.2 0.0 3.5e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Raptor_N PF14538.6 CBZ14623.1 - 2.4e-11 43.8 0.0 5.9e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 CBZ14623.1 - 0.11 13.4 0.4 2.1 9.4 0.0 2.9 2 0 0 2 2 2 0 WD domain, G-beta repeat DUF1935 PF09149.10 CBZ14624.1 - 2.8e-30 104.8 0.0 4.8e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.10 CBZ14625.1 - 8.1e-05 22.9 0.0 0.56 10.6 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1935) DUF1935 PF09149.10 CBZ14626.1 - 5.1e-07 30.0 0.0 6.4e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.10 CBZ14627.1 - 2.8e-30 104.8 0.0 3.7e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) NAP PF00956.18 CBZ14628.1 - 1.7e-12 47.1 1.7 2.1e-09 37.0 1.7 2.2 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) Mst1_SARAH PF11629.8 CBZ14628.1 - 0.024 14.7 0.3 0.082 13.0 0.3 1.9 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 DUF1935 PF09149.10 CBZ14629.1 - 7e-34 116.3 0.1 8.3e-34 116.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.10 CBZ14630.1 - 1.3e-38 131.5 0.2 1.5e-38 131.3 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) TraS PF10624.9 CBZ14630.1 - 0.063 13.2 0.0 0.083 12.8 0.0 1.2 1 0 0 1 1 1 0 Plasmid conjugative transfer entry exclusion protein TraS Thioredoxin_8 PF13905.6 CBZ14631.1 - 0.00037 20.8 0.0 0.00089 19.5 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin-like Pkinase PF00069.25 CBZ14632.1 - 5.3e-27 94.8 0.0 7.4e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ14632.1 - 1.5e-14 54.0 0.0 3.6e-14 52.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ14632.1 - 0.0034 16.8 0.0 0.086 12.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CBZ14632.1 - 0.061 12.1 0.0 0.088 11.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 CBZ14632.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Adaptin_N PF01602.20 CBZ14633.1 - 2.8e-63 214.3 7.6 4e-63 213.8 7.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 CBZ14633.1 - 2.3e-46 156.9 0.0 5.1e-46 155.8 0.0 1.6 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 CBZ14633.1 - 9.3e-42 142.3 0.0 2.1e-41 141.1 0.0 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT PF02985.22 CBZ14633.1 - 3.9e-06 26.6 3.2 0.67 10.4 0.0 5.5 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 CBZ14633.1 - 1e-05 25.9 9.1 0.13 12.7 0.0 5.0 6 0 0 6 6 6 3 HEAT repeats Cnd1 PF12717.7 CBZ14633.1 - 2.5e-05 24.4 5.3 0.00047 20.2 0.1 3.1 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF5471 PF17565.2 CBZ14633.1 - 0.0016 18.7 0.1 0.0043 17.3 0.1 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5471) TPP1 PF10341.9 CBZ14633.1 - 0.13 12.3 0.1 0.4 10.7 0.1 1.8 1 0 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD RNase_PH PF01138.21 CBZ14634.1 - 0.0096 16.4 0.2 0.023 15.2 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 PUF PF00806.19 CBZ14635.1 - 2.1e-19 68.0 0.0 0.0041 16.7 0.0 4.5 4 0 0 4 4 4 4 Pumilio-family RNA binding repeat MA3 PF02847.17 CBZ14635.1 - 0.053 13.5 0.2 0.9 9.5 0.0 2.3 2 0 0 2 2 2 0 MA3 domain Trimer_CC PF08954.11 CBZ14636.1 - 0.0084 15.6 0.3 0.0084 15.6 0.3 3.0 4 0 0 4 4 4 1 Trimerisation motif Beta-lactamase PF00144.24 CBZ14636.1 - 0.017 14.4 0.2 0.021 14.0 0.2 1.1 1 0 0 1 1 1 0 Beta-lactamase PUF PF00806.19 CBZ14638.1 - 1.2e-13 50.0 0.0 0.0017 18.0 0.0 3.4 3 0 0 3 3 3 3 Pumilio-family RNA binding repeat ANAPC4_WD40 PF12894.7 CBZ14639.1 - 0.013 15.8 0.0 1.4 9.3 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain AraC_binding PF02311.19 CBZ14639.1 - 3.1 7.7 5.3 4.7 7.1 0.1 2.4 2 0 0 2 2 2 0 AraC-like ligand binding domain Trimer_CC PF08954.11 CBZ14640.1 - 0.00019 20.9 22.8 0.0036 16.8 1.3 4.5 4 0 0 4 4 4 2 Trimerisation motif Macoilin PF09726.9 CBZ14640.1 - 0.0047 15.6 12.1 0.039 12.5 3.8 2.1 1 1 1 2 2 2 2 Macoilin family Tropomyosin_1 PF12718.7 CBZ14640.1 - 0.063 13.4 12.6 0.54 10.4 0.4 3.3 3 0 0 3 3 3 0 Tropomyosin like bZIP_1 PF00170.21 CBZ14640.1 - 0.27 11.4 5.3 1.6 8.9 2.5 2.7 2 0 0 2 2 2 0 bZIP transcription factor DUF1664 PF07889.12 CBZ14640.1 - 0.45 10.6 4.1 8.3 6.5 0.2 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Cep57_CLD_2 PF14197.6 CBZ14640.1 - 1.6 8.9 14.8 8.6 6.5 1.3 3.4 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 TPD52 PF04201.15 CBZ14640.1 - 3.2 7.3 9.0 0.068 12.8 0.9 2.2 3 0 0 3 3 3 0 Tumour protein D52 family Ax_dynein_light PF10211.9 CBZ14640.1 - 3.5 7.5 12.6 5.1 7.0 0.4 3.2 3 1 0 3 3 3 0 Axonemal dynein light chain Sipho_Gp157 PF05565.11 CBZ14640.1 - 3.7 7.5 8.6 3 7.8 0.9 2.7 3 0 0 3 3 3 0 Siphovirus Gp157 KxDL PF10241.9 CBZ14640.1 - 4.7 7.6 12.8 20 5.5 0.3 3.8 3 1 1 4 4 4 0 Uncharacterized conserved protein ADIP PF11559.8 CBZ14640.1 - 6.1 6.9 18.9 1.4 9.0 1.0 3.5 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding DUF4140 PF13600.6 CBZ14640.1 - 8.5 6.9 13.3 1.2 9.6 0.8 3.6 4 0 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) Arm PF00514.23 CBZ14641.1 - 2.7e-30 103.4 19.0 2.2e-05 24.3 0.1 8.4 9 0 0 9 9 9 7 Armadillo/beta-catenin-like repeat HEAT PF02985.22 CBZ14641.1 - 3.2e-15 54.9 13.0 0.039 14.2 0.1 8.1 9 0 0 9 9 7 4 HEAT repeat HEAT_2 PF13646.6 CBZ14641.1 - 2e-14 53.8 14.9 9.1e-05 22.8 0.1 5.0 2 2 1 4 4 4 4 HEAT repeats HEAT_EZ PF13513.6 CBZ14641.1 - 8.9e-14 51.6 18.8 0.026 15.0 0.8 6.4 5 1 2 7 7 6 5 HEAT-like repeat Cnd1 PF12717.7 CBZ14641.1 - 2.4e-12 47.2 0.2 0.002 18.2 0.0 3.7 2 1 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CBZ14641.1 - 7.3e-11 41.3 1.4 8.1e-08 31.3 2.5 3.0 2 1 0 2 2 2 2 Adaptin N terminal region DNA_alkylation PF08713.11 CBZ14641.1 - 1.7e-07 31.2 0.1 0.14 11.9 0.0 4.1 2 1 1 4 4 4 2 DNA alkylation repair enzyme CLASP_N PF12348.8 CBZ14641.1 - 0.00053 19.6 0.7 1.1 8.8 0.2 3.0 1 1 1 2 2 2 2 CLASP N terminal CHASE6_C PF17150.4 CBZ14641.1 - 0.0013 19.3 2.7 42 4.9 0.0 5.3 5 1 1 6 6 6 0 C-terminal domain of two-partite extracellular sensor domain V-ATPase_H_N PF03224.14 CBZ14641.1 - 0.0014 18.0 2.3 2.6 7.3 0.1 3.1 2 1 0 3 3 3 2 V-ATPase subunit H HEAT_PBS PF03130.16 CBZ14641.1 - 0.0019 18.7 9.5 0.2 12.4 0.5 5.5 6 0 0 6 6 4 1 PBS lyase HEAT-like repeat RICTOR_N PF14664.6 CBZ14641.1 - 0.0019 17.3 0.6 0.071 12.1 0.2 2.8 1 1 1 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term Mo25 PF08569.11 CBZ14641.1 - 0.0021 17.5 0.1 0.47 9.8 0.1 2.4 1 1 1 2 2 2 2 Mo25-like V-ATPase_H_C PF11698.8 CBZ14641.1 - 0.0023 18.0 0.3 0.3 11.2 0.2 3.6 3 2 1 4 4 4 2 V-ATPase subunit H Proteasom_PSMB PF10508.9 CBZ14641.1 - 0.0024 16.5 3.9 0.19 10.2 0.4 2.6 1 1 1 2 2 2 2 Proteasome non-ATPase 26S subunit Vac14_Fab1_bd PF12755.7 CBZ14641.1 - 0.032 14.8 0.2 0.98 10.1 0.1 3.1 1 1 3 4 4 4 0 Vacuolar 14 Fab1-binding region HEAT_UF PF18817.1 CBZ14641.1 - 0.059 13.6 0.0 3.7 7.9 0.0 3.4 3 0 0 3 3 3 0 Repeat of uncharacterized protein PH0542 DUF4244 PF14029.6 CBZ14642.1 - 0.21 11.1 2.0 0.27 10.7 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4244) SET PF00856.28 CBZ14644.1 - 0.00027 21.4 0.0 0.0016 18.9 0.0 1.9 1 1 0 1 1 1 1 SET domain ubiquitin PF00240.23 CBZ14646.1 - 0.00014 21.6 0.0 0.013 15.3 0.0 3.3 4 0 0 4 4 4 1 Ubiquitin family C2 PF00168.30 CBZ14647.1 - 0.13 12.6 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 C2 domain HEAT PF02985.22 CBZ14651.1 - 0.024 14.9 0.5 1.8 9.1 0.1 3.5 2 0 0 2 2 2 0 HEAT repeat DUF1834 PF08873.11 CBZ14651.1 - 0.03 14.1 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1834) DUF4456 PF14644.6 CBZ14654.1 - 1.1e-12 48.1 0.1 1.1e-12 48.1 0.1 4.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4456) DUF4455 PF14643.6 CBZ14654.1 - 1.1e-05 24.3 3.1 1.1e-05 24.3 3.1 4.0 4 1 0 4 4 4 1 Domain of unknown function (DUF4455) EMP24_GP25L PF01105.24 CBZ14654.1 - 0.31 11.0 2.1 26 4.7 1.6 3.3 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD DUF1400 PF07176.11 CBZ14654.1 - 0.36 11.1 4.1 0.43 10.9 0.4 2.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) Phage_GP20 PF06810.11 CBZ14654.1 - 2.3 8.0 5.6 0.42 10.4 0.8 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 AAA PF00004.29 CBZ14655.1 - 7.2e-25 87.9 0.0 4.2e-24 85.5 0.0 2.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBZ14655.1 - 3.8e-05 24.1 3.4 0.00031 21.2 1.4 3.4 2 2 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 CBZ14655.1 - 0.00021 21.8 0.0 0.00082 19.9 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 CBZ14655.1 - 0.00064 20.0 0.0 0.01 16.1 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBZ14655.1 - 0.014 15.9 0.0 0.03 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CBZ14655.1 - 0.044 13.7 3.8 1.4 8.8 0.1 3.5 2 2 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 CBZ14655.1 - 0.045 14.3 0.0 0.36 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CBZ14655.1 - 0.053 13.3 0.0 0.18 11.5 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 CBZ14655.1 - 0.062 13.3 0.2 0.44 10.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CBZ14655.1 - 0.064 13.4 0.2 0.25 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 CBZ14655.1 - 0.074 12.3 0.0 1.8 7.8 0.0 2.6 2 1 1 3 3 3 0 KAP family P-loop domain AAA_21 PF13304.6 CBZ14655.1 - 0.26 11.1 0.0 0.42 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 CBZ14655.1 - 0.56 9.7 4.3 6.3 6.3 0.2 3.3 2 1 1 3 3 3 0 AAA domain RabGAP-TBC PF00566.18 CBZ14656.1 - 5.2e-15 55.7 0.1 1e-14 54.7 0.1 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SGS PF05002.15 CBZ14657.1 - 9.1e-32 109.0 0.6 1.5e-31 108.3 0.6 1.4 1 0 0 1 1 1 1 SGS domain CS PF04969.16 CBZ14657.1 - 0.00056 20.9 0.0 0.0012 19.9 0.0 1.6 1 0 0 1 1 1 1 CS domain BsuPI PF12690.7 CBZ14657.1 - 0.015 15.3 0.1 0.038 14.0 0.1 1.6 1 0 0 1 1 1 0 Intracellular proteinase inhibitor Ribosomal_S17_N PF16205.5 CBZ14658.1 - 4.8e-28 97.3 0.7 4.8e-28 97.3 0.7 1.6 2 0 0 2 2 2 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 CBZ14658.1 - 3.5e-22 78.3 0.5 3.5e-22 78.3 0.5 2.0 2 0 0 2 2 2 1 Ribosomal protein S17 DnaB_2 PF07261.11 CBZ14659.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Replication initiation and membrane attachment KleE PF17394.2 CBZ14659.1 - 1.2 9.4 5.1 0.45 10.7 2.1 1.9 2 0 0 2 2 2 0 Uncharacterized KleE stable inheritance protein Brix PF04427.18 CBZ14660.1 - 7.4e-34 117.6 0.0 1.1e-33 117.0 0.0 1.3 1 0 0 1 1 1 1 Brix domain Peptidase_C50 PF03568.17 CBZ14661.1 - 1.7e-37 129.5 0.1 5.6e-36 124.5 0.1 2.5 1 1 0 1 1 1 1 Peptidase family C50 CHAT PF12770.7 CBZ14661.1 - 2.8e-08 33.5 0.4 0.00035 20.1 0.1 2.8 2 0 0 2 2 2 2 CHAT domain SNAP PF14938.6 CBZ14662.1 - 3.4e-58 197.3 11.7 3.8e-58 197.1 11.7 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 CBZ14662.1 - 2.3e-07 31.0 7.0 1.8e-06 28.2 1.1 3.1 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 CBZ14662.1 - 0.0037 16.7 2.6 0.0067 15.8 2.3 1.5 1 1 0 1 1 1 1 MalT-like TPR region TPR_8 PF13181.6 CBZ14662.1 - 0.013 15.6 9.9 0.26 11.6 0.7 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ14662.1 - 0.015 15.3 1.5 2.5 8.3 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Foie-gras_1 PF11817.8 CBZ14662.1 - 0.032 13.8 0.5 0.075 12.6 0.5 1.7 1 0 0 1 1 1 0 Foie gras liver health family 1 TPR_1 PF00515.28 CBZ14662.1 - 0.064 13.1 0.7 0.064 13.1 0.7 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ14662.1 - 0.091 13.4 17.9 0.88 10.3 0.1 5.7 4 3 1 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ14662.1 - 0.11 13.2 7.3 4.6 8.0 0.3 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF1033 PF06279.11 CBZ14662.1 - 0.15 12.3 0.1 0.15 12.3 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1033) TPR_2 PF07719.17 CBZ14662.1 - 0.28 11.4 12.7 2.3 8.5 0.4 5.5 4 2 0 5 5 5 0 Tetratricopeptide repeat tRNA_U5-meth_tr PF05958.11 CBZ14664.1 - 4.5e-18 65.4 0.0 4.3e-17 62.1 0.0 2.1 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 CBZ14664.1 - 3e-10 40.1 0.0 5.1e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ14664.1 - 3.4e-09 37.3 0.0 9.8e-09 35.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 CBZ14664.1 - 4.8e-06 26.3 0.0 8.6e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PCMT PF01135.19 CBZ14664.1 - 1.9e-05 24.6 0.0 3.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 CBZ14664.1 - 5.7e-05 23.7 0.0 0.00023 21.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 CBZ14664.1 - 7.8e-05 22.3 0.0 0.00015 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 CBZ14664.1 - 8.2e-05 22.0 0.0 0.00018 20.9 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 CBZ14664.1 - 0.00045 19.8 0.0 0.00077 19.1 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_4 PF02390.17 CBZ14664.1 - 0.0094 15.4 0.0 0.019 14.4 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.6 CBZ14664.1 - 0.011 15.7 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 CBZ14664.1 - 0.015 14.7 0.1 0.027 13.9 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TPMT PF05724.11 CBZ14664.1 - 0.018 14.7 0.0 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) DOT1 PF08123.13 CBZ14664.1 - 0.021 14.4 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_18 PF12847.7 CBZ14664.1 - 0.058 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RNA_ligase PF09414.10 CBZ14666.1 - 2.9e-22 79.7 0.0 4.2e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 RNA ligase T4_Rnl2_C PF18043.1 CBZ14666.1 - 8.1e-09 35.5 0.0 1.6e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 T4 RNA ligase 2 C-terminal Osmo_MPGsynth PF09488.10 CBZ14667.1 - 0.17 10.6 0.0 0.29 9.8 0.0 1.4 1 1 0 1 1 1 0 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) Peptidase_M20 PF01546.28 CBZ14668.1 - 2.5e-31 109.0 0.2 3.2e-31 108.7 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CBZ14668.1 - 1.5e-09 37.8 0.0 3.3e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CBZ14668.1 - 0.095 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M28 Peptidase_M20 PF01546.28 CBZ14669.1 - 1.2e-30 106.7 0.2 1.8e-30 106.2 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CBZ14669.1 - 9.4e-10 38.4 0.0 2.2e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CBZ14669.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 Peptidase_M20 PF01546.28 CBZ14670.1 - 1.4e-29 103.3 0.5 1.8e-29 103.0 0.5 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CBZ14670.1 - 2e-09 37.3 0.0 5.1e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CBZ14670.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M28 PPR_2 PF13041.6 CBZ14671.1 - 1.4e-16 60.4 1.7 4.1e-05 23.7 0.0 5.5 5 0 0 5 5 5 3 PPR repeat family PPR_3 PF13812.6 CBZ14671.1 - 2.3e-15 56.4 0.1 2.9e-05 24.0 0.0 5.1 4 1 0 5 5 5 3 Pentatricopeptide repeat domain PPR_long PF17177.4 CBZ14671.1 - 2.6e-12 46.6 0.8 4.1e-05 23.0 0.0 3.5 2 1 1 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 CBZ14671.1 - 3.8e-05 23.3 0.0 2.2 8.0 0.0 5.0 5 0 0 5 5 5 2 PPR repeat PPR PF01535.20 CBZ14671.1 - 0.00012 22.1 5.9 0.46 10.9 0.2 5.5 6 0 0 6 6 6 2 PPR repeat Pkr1 PF08636.10 CBZ14672.1 - 1.5e-06 28.2 7.6 1.9e-06 27.9 7.6 1.1 1 0 0 1 1 1 1 ER protein Pkr1 ANAPC4_WD40 PF12894.7 CBZ14673.1 - 0.028 14.7 0.0 0.11 12.7 0.0 2.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain CHORD PF04968.12 CBZ14675.1 - 9.7e-40 135.1 33.5 7.1e-21 74.7 12.6 2.4 2 0 0 2 2 2 2 CHORD Rep_trans PF02486.19 CBZ14676.1 - 0.072 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Replication initiation factor Abhydrolase_1 PF00561.20 CBZ14677.1 - 0.00046 19.9 0.1 0.0022 17.7 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 CBZ14677.1 - 0.025 14.1 0.3 0.081 12.5 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family Peptidase_S9 PF00326.21 CBZ14677.1 - 0.06 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Vps39_2 PF10367.9 CBZ14678.1 - 1.7e-25 89.5 0.6 4.4e-25 88.2 0.6 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 CBZ14678.1 - 3.5e-06 27.2 0.1 2.8e-05 24.4 0.1 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.22 CBZ14678.1 - 5.9e-06 26.1 0.0 1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.20 CBZ14678.1 - 0.00024 21.0 0.0 0.016 15.1 0.0 2.5 2 1 0 2 2 2 1 Region in Clathrin and VPS Rad50_zn_hook PF04423.14 CBZ14678.1 - 0.11 12.4 0.4 0.36 10.7 0.0 2.0 2 0 0 2 2 2 0 Rad50 zinc hook motif Baculo_LEF5_C PF11792.8 CBZ14678.1 - 0.14 11.9 0.0 0.93 9.2 0.0 2.4 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain FAM91_C PF14648.6 CBZ14679.1 - 2.9e-117 392.1 0.0 4.2e-115 385.0 0.0 2.1 1 1 0 1 1 1 1 FAM91 C-terminus FAM91_N PF14647.6 CBZ14679.1 - 1.3e-99 333.4 0.1 1.9e-99 332.9 0.1 1.2 1 0 0 1 1 1 1 FAM91 N-terminus RNase_H2_suC PF08615.11 CBZ14680.1 - 1.1e-10 41.8 0.0 1.5e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) SET PF00856.28 CBZ14681.1 - 2.9e-09 37.5 0.1 5.8e-09 36.6 0.1 1.5 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 CBZ14681.1 - 1.4e-05 25.1 5.6 1.4e-05 25.1 5.6 2.8 2 0 0 2 2 2 1 MYND finger TPR_1 PF00515.28 CBZ14681.1 - 0.0099 15.7 0.7 2.5 8.1 0.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ14681.1 - 0.01 15.9 0.1 0.18 12.0 0.3 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ14681.1 - 0.062 13.6 0.4 0.23 11.8 0.4 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat PrmA PF06325.13 CBZ14684.1 - 1.3e-12 47.7 0.0 2.1e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 CBZ14684.1 - 3.2e-12 46.5 0.2 5.1e-12 45.8 0.2 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ14684.1 - 5e-12 46.4 0.1 1.2e-11 45.2 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ14684.1 - 1.3e-08 35.4 0.0 2.8e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBZ14684.1 - 2.2e-07 30.9 0.0 3.1e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CBZ14684.1 - 7.9e-07 28.8 0.2 1.3e-06 28.1 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 CBZ14684.1 - 5.4e-06 25.5 0.0 7.5e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 CBZ14684.1 - 1e-05 26.2 0.0 2e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 CBZ14684.1 - 1.6e-05 24.4 0.3 3.3e-05 23.4 0.3 1.5 1 1 0 1 1 1 1 Tellurite resistance protein TehB CMAS PF02353.20 CBZ14684.1 - 2.4e-05 23.8 0.1 3.7e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 CBZ14684.1 - 0.00013 21.9 0.1 0.00021 21.3 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 CBZ14684.1 - 0.0007 19.5 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase NodS PF05401.11 CBZ14684.1 - 0.0055 16.4 0.1 0.0085 15.7 0.1 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 CBZ14684.1 - 0.0065 15.8 0.1 0.0099 15.2 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 CBZ14684.1 - 0.012 15.6 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 CBZ14684.1 - 0.016 15.3 0.1 0.026 14.7 0.1 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 CBZ14684.1 - 0.03 14.1 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 CBZ14684.1 - 0.034 15.2 0.0 0.07 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 CBZ14684.1 - 0.054 13.2 0.0 0.083 12.6 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Phage_integrase PF00589.22 CBZ14685.1 - 6.1e-07 29.4 0.3 6.8e-06 26.0 0.0 2.8 3 1 0 3 3 3 1 Phage integrase family RVT_1 PF00078.27 CBZ14685.1 - 0.0022 17.5 0.0 0.008 15.7 0.0 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A17 PF05380.13 CBZ14685.1 - 0.0035 17.4 0.1 0.044 13.8 0.0 2.4 1 1 1 2 2 2 1 Pao retrotransposon peptidase Phage_integrase PF00589.22 CBZ14686.1 - 7.5e-06 25.8 0.1 6e-05 22.9 0.0 2.6 3 1 0 3 3 3 1 Phage integrase family RVT_1 PF00078.27 CBZ14686.1 - 0.0026 17.3 0.0 0.007 15.9 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A17 PF05380.13 CBZ14686.1 - 0.0032 17.5 0.1 0.038 14.0 0.0 2.4 1 1 1 2 2 2 1 Pao retrotransposon peptidase Phage_integrase PF00589.22 CBZ14687.1 - 6.6e-07 29.3 0.0 3e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 Phage integrase family Phage_integrase PF00589.22 CBZ14689.1 - 7.6e-07 29.1 0.0 4.4e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 Phage integrase family RVT_1 PF00078.27 CBZ14689.1 - 0.0026 17.3 0.0 0.0065 16.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A17 PF05380.13 CBZ14689.1 - 0.0044 17.1 0.1 0.049 13.6 0.0 2.3 1 1 1 2 2 2 1 Pao retrotransposon peptidase Phage_integrase PF00589.22 CBZ14690.1 - 4.6e-05 23.3 0.9 0.0006 19.6 0.0 3.3 4 1 0 4 4 4 1 Phage integrase family RVT_1 PF00078.27 CBZ14690.1 - 0.0023 17.5 0.0 0.0058 16.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A17 PF05380.13 CBZ14690.1 - 0.0031 17.5 0.1 0.043 13.8 0.0 2.5 1 1 1 2 2 2 1 Pao retrotransposon peptidase Phage_integrase PF00589.22 CBZ14692.1 - 5.5e-06 26.3 0.1 6e-05 22.9 0.0 2.9 3 0 0 3 3 3 1 Phage integrase family RVT_1 PF00078.27 CBZ14692.1 - 0.0021 17.6 0.0 0.0054 16.3 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A17 PF05380.13 CBZ14692.1 - 0.0028 17.7 0.1 0.039 14.0 0.0 2.4 1 1 1 2 2 2 1 Pao retrotransposon peptidase Galactosyl_T PF01762.21 CBZ14693.1 - 0.0015 18.4 0.7 0.0049 16.7 0.0 2.2 4 0 0 4 4 4 1 Galactosyltransferase MVP_shoulder PF11978.8 CBZ14694.1 - 1e-41 141.7 0.0 1.6e-41 141.0 0.0 1.3 1 0 0 1 1 1 1 Shoulder domain Vault_3 PF17795.1 CBZ14694.1 - 8.3e-33 112.2 0.3 3.2e-31 107.2 0.1 2.4 2 0 0 2 2 2 1 Major Vault Protein Repeat domain Vault_4 PF17796.1 CBZ14694.1 - 5.6e-15 55.2 0.0 2.2e-13 50.1 0.0 2.5 2 0 0 2 2 2 1 Major Vault Protein repeat domain Vault PF01505.18 CBZ14694.1 - 7.4e-12 45.2 0.1 1.4e-11 44.3 0.1 1.5 1 0 0 1 1 1 1 Major Vault Protein repeat domain DnaJ_C PF01556.18 CBZ14695.1 - 5.5e-31 107.6 0.0 8.3e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CBZ14695.1 - 1.3e-26 92.5 1.9 2.2e-26 91.7 1.9 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CBZ14695.1 - 4.4e-13 49.4 14.5 8.4e-13 48.5 14.5 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CBZ14695.1 - 0.041 13.8 7.7 0.42 10.6 1.1 2.6 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein DZR PF12773.7 CBZ14695.1 - 0.056 13.5 6.1 0.48 10.5 0.4 2.4 2 0 0 2 2 2 0 Double zinc ribbon Lactamase_B PF00753.27 CBZ14696.1 - 1.1e-17 64.7 0.3 4.2e-17 62.8 0.1 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 CBZ14696.1 - 2.9e-11 43.1 0.0 6.3e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 CBZ14696.1 - 9.9e-05 21.9 0.2 0.00028 20.5 0.1 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CBZ14696.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.7 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Stork_head PF10264.9 CBZ14697.1 - 0.065 13.4 0.1 0.23 11.6 0.0 1.9 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain Cpn60_TCP1 PF00118.24 CBZ14700.1 - 2.3e-142 475.1 9.6 2.8e-142 474.8 9.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Colicin PF01024.19 CBZ14700.1 - 0.0055 16.6 0.1 0.027 14.4 0.2 2.0 2 0 0 2 2 2 1 Colicin pore forming domain Sde2_N_Ubi PF13019.6 CBZ14700.1 - 0.34 10.7 1.9 1 9.2 1.9 1.7 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain HA2 PF04408.23 CBZ14709.1 - 1.1e-17 64.3 0.0 2.6e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CBZ14709.1 - 2.3e-14 53.7 0.0 5.2e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBZ14709.1 - 1.6e-07 31.3 0.0 3.6e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CBZ14709.1 - 1.9e-06 28.2 0.0 6.4e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain R3H PF01424.22 CBZ14709.1 - 0.0051 16.8 0.0 0.017 15.1 0.0 2.0 1 0 0 1 1 1 1 R3H domain AAA_19 PF13245.6 CBZ14709.1 - 0.0058 17.0 0.0 0.028 14.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 CBZ14709.1 - 0.016 14.2 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Methyltransf_32 PF13679.6 CBZ14717.1 - 0.00093 19.2 1.3 0.0084 16.1 1.3 2.3 1 1 0 1 1 1 1 Methyltransferase domain TRM13 PF05206.14 CBZ14717.1 - 0.051 13.1 0.0 0.094 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase TRM13 Sigma70_r4 PF04545.16 CBZ14717.1 - 0.061 12.8 0.5 3.8 7.1 0.0 2.5 2 0 0 2 2 2 0 Sigma-70, region 4 Ribosomal_S8e PF01201.22 CBZ14720.1 - 9.2e-47 158.7 2.4 1.1e-46 158.4 2.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e SpoU_methylase PF00588.19 CBZ14721.1 - 4.6e-16 59.3 0.1 2.1e-09 37.7 0.0 2.4 2 0 0 2 2 2 2 SpoU rRNA Methylase family DUF2442 PF10387.9 CBZ14721.1 - 0.011 16.0 0.1 0.087 13.1 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2442) GIY-YIG PF01541.24 CBZ14723.1 - 1e-10 41.7 0.0 1.8e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain YacG PF03884.14 CBZ14723.1 - 7.3 6.4 6.7 0.94 9.3 0.8 2.3 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG DHHC PF01529.20 CBZ14724.1 - 7.1e-35 120.0 3.9 7.1e-35 120.0 3.9 2.0 2 1 0 2 2 2 1 DHHC palmitoyltransferase Yip1 PF04893.17 CBZ14724.1 - 0.085 12.6 0.1 0.085 12.6 0.1 2.1 2 0 0 2 2 2 0 Yip1 domain LPG_synthase_TM PF03706.13 CBZ14724.1 - 2 7.8 10.9 0.71 9.3 1.4 2.1 2 0 0 2 2 2 0 Lysylphosphatidylglycerol synthase TM region LRR_8 PF13855.6 CBZ14725.1 - 6.7e-09 35.4 12.9 6.7e-06 25.8 2.6 2.2 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CBZ14725.1 - 1.7e-08 34.6 3.9 0.0021 18.4 0.3 3.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) EF-hand_7 PF13499.6 CBZ14725.1 - 9.3e-06 26.0 0.0 4.1e-05 23.9 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain pair LRR_6 PF13516.6 CBZ14725.1 - 0.00016 21.5 0.5 0.35 11.1 0.2 3.0 2 0 0 2 2 2 2 Leucine Rich repeat EF-hand_1 PF00036.32 CBZ14725.1 - 0.00087 18.7 0.1 0.013 15.0 0.0 3.0 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 CBZ14725.1 - 0.0021 17.9 0.0 0.022 14.6 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 CBZ14725.1 - 0.0084 15.9 0.1 0.25 11.2 0.0 2.8 1 1 1 2 2 2 1 EF-hand domain pair LRR_1 PF00560.33 CBZ14725.1 - 0.012 16.1 2.9 0.74 10.6 0.1 3.0 2 0 0 2 2 2 0 Leucine Rich Repeat REV1_C PF16727.5 CBZ14725.1 - 0.019 15.4 1.4 0.14 12.6 0.2 2.5 2 0 0 2 2 2 0 DNA repair protein REV1 C-terminal domain 7TMR-HDED PF07697.11 CBZ14725.1 - 0.028 14.5 1.5 2.4 8.2 1.5 2.5 1 1 0 1 1 1 0 7TM-HD extracellular SIR2 PF02146.17 CBZ14728.1 - 3.9e-39 134.4 0.0 5.6e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 Sir2 family zinc_ribbon_4 PF13717.6 CBZ14728.1 - 0.00082 19.2 1.9 0.0023 17.8 0.3 2.2 2 0 0 2 2 2 1 zinc-ribbon domain Paired_CXXCH_1 PF09699.10 CBZ14728.1 - 0.02 14.7 0.5 0.041 13.6 0.5 1.5 1 0 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) RNA_pol_Rpc4 PF05132.14 CBZ14728.1 - 0.11 12.9 0.3 0.17 12.3 0.3 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 MethyTransf_Reg PF10119.9 CBZ14729.1 - 0.02 15.6 0.1 0.14 12.9 0.0 2.5 2 1 1 3 3 3 0 Predicted methyltransferase regulatory domain ELYS PF13934.6 CBZ14729.1 - 0.059 13.3 1.0 0.19 11.6 1.0 1.8 1 1 0 1 1 1 0 Nuclear pore complex assembly LRV PF01816.17 CBZ14729.1 - 1.2 9.6 3.8 3.6 8.2 0.5 2.9 3 0 0 3 3 3 0 Leucine rich repeat variant Peptidase_M1 PF01433.20 CBZ14730.1 - 7.4e-75 251.2 1.0 1.7e-74 250.1 0.6 1.7 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 CBZ14730.1 - 4.3e-49 167.8 0.0 7e-49 167.1 0.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 CBZ14730.1 - 3.9e-40 138.0 0.0 6.8e-40 137.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain TROVE PF05731.11 CBZ14731.1 - 2.5e-61 208.1 0.0 3e-33 115.5 0.0 2.6 2 1 0 2 2 2 2 TROVE domain WD40 PF00400.32 CBZ14731.1 - 5.5e-12 46.0 15.5 0.0083 17.0 0.1 9.6 10 0 0 10 10 10 3 WD domain, G-beta repeat DUF4062 PF13271.6 CBZ14731.1 - 4.5e-11 43.0 0.0 1.6e-10 41.2 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4062) APG9 PF04109.16 CBZ14737.1 - 1.8e-59 202.1 5.2 3.5e-59 201.1 5.2 1.4 1 1 0 1 1 1 1 Autophagy protein Apg9 Glutaredoxin PF00462.24 CBZ14738.1 - 1.6e-14 53.8 0.2 2.5e-14 53.2 0.2 1.3 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 CBZ14738.1 - 1.4e-05 25.4 0.0 1.7e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_3 PF13192.6 CBZ14738.1 - 0.001 19.0 0.1 0.0015 18.5 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin domain DSBA PF01323.20 CBZ14738.1 - 0.0042 16.9 0.3 0.49 10.2 0.2 2.1 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 CBZ14738.1 - 0.006 16.8 0.3 0.66 10.1 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin DUF836 PF05768.14 CBZ14738.1 - 0.014 15.8 0.0 0.017 15.5 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 CBZ14738.1 - 0.033 14.6 0.3 0.045 14.2 0.3 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain DUF846 PF05832.12 CBZ14744.1 - 7.4e-44 149.2 12.5 1e-43 148.7 12.5 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Methyltransf_25 PF13649.6 CBZ14748.1 - 0.08 13.7 0.0 0.19 12.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Amastin PF07344.11 CBZ14754.1 - 3.8e-35 121.0 12.8 6.7e-35 120.2 12.8 1.4 1 0 0 1 1 1 1 Amastin surface glycoprotein PEN-2 PF10251.9 CBZ14754.1 - 0.0019 18.6 0.2 0.0019 18.6 0.2 1.8 2 0 0 2 2 2 1 Presenilin enhancer-2 subunit of gamma secretase MINDY_DUB PF04424.13 CBZ14754.1 - 0.077 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 MINDY deubiquitinase Molydop_binding PF01568.21 CBZ14754.1 - 0.085 12.9 0.1 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain PMP22_Claudin PF00822.20 CBZ14754.1 - 2.1 8.2 8.7 3.3 7.5 8.7 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family SUR7 PF06687.12 CBZ14754.1 - 3.1 7.4 14.6 3.9 7.0 12.2 2.0 1 1 1 2 2 2 0 SUR7/PalI family Sua5_yciO_yrdC PF01300.18 CBZ14756.1 - 1.5e-46 158.2 0.0 2.1e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 CBZ14756.1 - 1.7e-12 48.1 0.0 2.7e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Ribosomal_S14 PF00253.21 CBZ14757.1 - 2.5e-11 43.1 3.5 2.7e-11 43.0 3.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e GCD14 PF08704.10 CBZ14758.1 - 3.9e-64 216.7 0.8 3.1e-38 131.8 0.0 3.0 1 1 2 3 3 3 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 CBZ14758.1 - 3.9e-09 36.5 0.0 9.2e-09 35.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ14758.1 - 1.4e-07 32.1 0.1 0.00055 20.6 0.0 2.5 1 1 1 2 2 2 2 Methyltransferase domain PCMT PF01135.19 CBZ14758.1 - 2.1e-06 27.6 0.0 5.6e-06 26.3 0.0 1.7 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14_N PF14801.6 CBZ14758.1 - 3e-05 23.8 0.3 7.3e-05 22.5 0.3 1.7 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Fibrillarin PF01269.17 CBZ14758.1 - 0.00016 20.9 0.0 0.092 11.8 0.0 2.3 2 0 0 2 2 2 2 Fibrillarin Methyltransf_11 PF08241.12 CBZ14758.1 - 0.00027 21.5 0.1 0.00071 20.2 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 CBZ14758.1 - 0.0026 18.7 0.1 0.0065 17.5 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ14758.1 - 0.0041 17.8 0.0 0.054 14.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBZ14758.1 - 0.006 15.9 0.0 0.049 13.0 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 CBZ14758.1 - 0.0072 15.9 0.0 0.024 14.2 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase small domain Methyltr_RsmB-F PF01189.17 CBZ14758.1 - 0.013 15.1 0.1 0.053 13.2 0.1 2.0 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F RrnaAD PF00398.20 CBZ14758.1 - 0.021 13.9 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PrmA PF06325.13 CBZ14758.1 - 0.03 13.7 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 CBZ14758.1 - 0.092 12.0 0.0 0.18 11.0 0.0 1.4 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Ribosomal_S14 PF00253.21 CBZ14760.1 - 2.5e-11 43.1 3.5 2.7e-11 43.0 3.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e zf-CCHC_2 PF13696.6 CBZ14762.1 - 7e-08 32.1 4.2 1.3e-07 31.3 4.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_jaz PF12171.8 CBZ14762.1 - 0.00028 21.1 0.2 0.00077 19.7 0.1 1.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Rubredoxin_2 PF18073.1 CBZ14762.1 - 0.028 14.1 1.8 0.028 14.1 1.8 1.8 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-CCHC_5 PF14787.6 CBZ14762.1 - 0.029 14.1 1.1 0.078 12.7 1.1 1.8 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger eIF3g PF12353.8 CBZ14762.1 - 0.034 14.5 0.0 0.09 13.2 0.0 1.7 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G NUFIP1 PF10453.9 CBZ14762.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-LITAF-like PF10601.9 CBZ14762.1 - 0.06 13.6 0.4 0.14 12.5 0.4 1.5 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain zf-C2H2_4 PF13894.6 CBZ14762.1 - 0.22 12.5 0.1 0.22 12.5 0.1 3.4 2 1 1 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CBZ14762.1 - 0.39 11.3 0.1 0.39 11.3 0.1 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type Methyltr_RsmB-F PF01189.17 CBZ14768.1 - 1.8e-38 132.2 0.1 9.4e-37 126.6 0.1 2.3 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 CBZ14768.1 - 6.9e-05 23.0 0.0 0.00018 21.7 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase Bombolitin PF08096.11 CBZ14768.1 - 0.4 11.0 1.3 0.86 10.0 1.3 1.5 1 0 0 1 1 1 0 Bombolitin family Arf PF00025.21 CBZ14778.1 - 1.2e-47 161.6 0.0 1.3e-47 161.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CBZ14778.1 - 4.5e-17 62.1 0.0 5.7e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CBZ14778.1 - 1.3e-09 37.7 0.0 3.3e-05 23.2 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CBZ14778.1 - 1.7e-09 37.5 0.0 2.3e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 CBZ14778.1 - 2.4e-09 37.3 0.0 3.2e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 CBZ14778.1 - 1.1e-08 35.3 0.0 1.7e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 CBZ14778.1 - 2.9e-05 23.6 0.0 5.7e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 CBZ14778.1 - 0.0021 17.6 0.1 0.0042 16.6 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_18 PF13238.6 CBZ14778.1 - 0.0025 18.4 0.0 0.0048 17.4 0.0 1.5 1 1 1 2 2 2 1 AAA domain TniB PF05621.11 CBZ14778.1 - 0.0046 16.4 0.0 0.0059 16.0 0.0 1.2 1 0 0 1 1 1 1 Bacterial TniB protein AAA_24 PF13479.6 CBZ14778.1 - 0.0061 16.3 0.0 0.0082 15.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 CBZ14778.1 - 0.014 14.3 0.0 0.11 11.4 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NOG1 PF06858.14 CBZ14778.1 - 0.015 15.1 0.1 0.026 14.3 0.1 1.4 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) GTP_EFTU PF00009.27 CBZ14778.1 - 0.058 12.9 0.3 1.9 8.0 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain DLIC PF05783.11 CBZ14778.1 - 0.11 11.4 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) DUF4831 PF16115.5 CBZ14781.1 - 0.14 11.1 0.2 0.2 10.7 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4831) FtsJ PF01728.19 CBZ14784.1 - 1.6e-37 129.3 0.0 2.1e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase LRR_4 PF12799.7 CBZ14786.1 - 3e-24 84.7 29.9 0.00011 22.5 0.0 11.4 10 2 2 12 12 12 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ14786.1 - 6.8e-08 32.2 28.9 0.00023 20.9 0.8 8.3 6 2 6 12 12 12 5 Leucine rich repeat LRR_9 PF14580.6 CBZ14786.1 - 0.0039 16.7 6.3 2 7.9 0.3 4.9 1 1 3 5 5 5 1 Leucine-rich repeat LRR_6 PF13516.6 CBZ14786.1 - 0.0047 16.9 29.0 0.19 11.9 0.0 10.9 14 0 0 14 14 14 1 Leucine Rich repeat LRR_2 PF07723.13 CBZ14786.1 - 0.0099 16.5 1.6 18 6.2 0.1 4.4 4 0 0 4 4 4 1 Leucine Rich Repeat WAP PF00095.21 CBZ14786.1 - 2.1 8.8 6.0 0.28 11.6 1.0 2.2 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' Orf78 PF06024.12 CBZ14789.1 - 0.012 15.9 0.0 0.022 15.1 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) Peptidase_M61 PF05299.12 CBZ14789.1 - 0.037 14.4 0.0 0.07 13.5 0.0 1.4 1 0 0 1 1 1 0 M61 glycyl aminopeptidase 7tm_1 PF00001.21 CBZ14789.1 - 0.079 12.3 0.0 0.079 12.3 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) KxDL PF10241.9 CBZ14803.1 - 0.0044 17.3 0.8 0.017 15.4 0.8 2.0 1 0 0 1 1 1 1 Uncharacterized conserved protein TRPM_tetra PF16519.5 CBZ14803.1 - 0.0071 16.4 0.8 0.29 11.2 0.6 2.8 2 0 0 2 2 2 1 Tetramerisation domain of TRPM Vac_Fusion PF02346.16 CBZ14803.1 - 0.055 13.1 0.7 0.39 10.4 0.1 2.5 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 DUF4219 PF13961.6 CBZ14803.1 - 0.14 11.8 0.2 0.31 10.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) Ribo_biogen_C PF04034.13 CBZ14806.1 - 1.4e-50 170.2 0.0 1.9e-50 169.9 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 CBZ14806.1 - 4.1e-11 42.5 0.0 7.7e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Synaptobrevin PF00957.21 CBZ14807.1 - 6.7e-09 35.4 4.2 1.4e-08 34.4 4.2 1.4 1 0 0 1 1 1 1 Synaptobrevin BolA PF01722.18 CBZ14814.1 - 1e-15 57.8 0.1 3.4e-15 56.1 0.1 1.7 1 1 0 1 1 1 1 BolA-like protein UDPGP PF01704.18 CBZ14819.1 - 6.1e-28 97.6 0.0 8.9e-28 97.1 0.0 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 CBZ14819.1 - 0.004 17.5 0.9 0.012 15.9 0.3 2.1 2 0 0 2 2 2 1 MobA-like NTP transferase domain SH2_2 PF14633.6 CBZ14822.1 - 1.9e-21 76.5 0.1 3.5e-21 75.6 0.1 1.3 1 0 0 1 1 1 1 SH2 domain YqgF PF14639.6 CBZ14822.1 - 8.1e-11 41.9 0.0 6.9e-10 38.9 0.0 2.2 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 Tex_YqgF PF16921.5 CBZ14822.1 - 0.0013 19.2 0.0 0.0031 18.0 0.0 1.6 1 0 0 1 1 1 1 Tex protein YqgF-like domain HHH_7 PF14635.6 CBZ14822.1 - 0.065 13.6 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif HTH_5 PF01022.20 CBZ14822.1 - 0.15 11.9 0.1 0.48 10.3 0.1 1.8 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family CENP-T_C PF15511.6 CBZ14824.1 - 1e-05 25.6 0.1 1.7e-05 24.9 0.0 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CBZ14824.1 - 0.00056 20.0 0.1 0.00088 19.4 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 CBZ14824.1 - 0.00058 20.1 0.4 0.00081 19.6 0.0 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 CBZ14824.1 - 0.0025 17.8 0.0 0.0029 17.6 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 CBZ14824.1 - 0.0042 17.4 1.7 0.0082 16.5 1.7 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CBZ14824.1 - 0.063 13.3 0.0 0.083 13.0 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 CBZ14825.1 - 1e-05 25.6 0.1 1.7e-05 24.9 0.0 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CBZ14825.1 - 0.00056 20.0 0.1 0.00088 19.4 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 CBZ14825.1 - 0.00058 20.1 0.4 0.00081 19.6 0.0 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 CBZ14825.1 - 0.0025 17.8 0.0 0.0029 17.6 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 CBZ14825.1 - 0.0042 17.4 1.7 0.0082 16.5 1.7 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CBZ14825.1 - 0.063 13.3 0.0 0.083 13.0 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Aminotran_1_2 PF00155.21 CBZ14826.1 - 3.6e-48 164.6 0.0 4.3e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 CBZ14826.1 - 0.0071 15.7 0.0 0.064 12.5 0.0 2.0 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Yos1 PF08571.10 CBZ14832.1 - 2.6e-25 88.5 0.1 4.2e-25 87.8 0.1 1.3 1 1 0 1 1 1 1 Yos1-like zf-RING_2 PF13639.6 CBZ14833.1 - 4.5e-09 36.5 14.7 4.9e-05 23.6 0.5 3.9 3 1 0 3 3 3 2 Ring finger domain zf-RING_5 PF14634.6 CBZ14833.1 - 2.3e-07 30.7 15.4 0.00031 20.7 0.6 4.3 3 1 0 3 3 3 2 zinc-RING finger domain zf-RING_UBOX PF13445.6 CBZ14833.1 - 8.7e-06 25.7 20.3 0.0096 15.9 0.1 5.3 5 0 0 5 5 5 2 RING-type zinc-finger zf-RING_11 PF17123.5 CBZ14833.1 - 1.1e-05 25.0 6.4 0.0017 18.1 1.1 4.4 4 1 0 4 4 4 2 RING-like zinc finger IQ PF00612.27 CBZ14833.1 - 0.00017 21.1 1.6 0.00059 19.4 1.6 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif Prok-RING_4 PF14447.6 CBZ14833.1 - 0.00018 21.3 13.9 0.99 9.3 0.1 5.2 5 0 0 5 5 5 1 Prokaryotic RING finger family 4 Zf_RING PF16744.5 CBZ14833.1 - 0.011 15.8 7.8 0.021 15.0 0.3 3.8 3 2 1 4 4 4 0 KIAA1045 RING finger zf-C3HC4 PF00097.25 CBZ14833.1 - 0.017 15.0 15.5 0.55 10.2 0.1 4.7 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBZ14833.1 - 0.058 13.2 23.7 0.14 12.1 0.3 5.0 5 0 0 5 5 5 0 Zinc finger, C3HC4 type (RING finger) NAPRTase_C PF17956.1 CBZ14833.1 - 0.12 12.8 0.0 22 5.5 0.1 2.5 2 0 0 2 2 2 0 Nicotinate phosphoribosyltransferase C-terminal domain Zn_ribbon_17 PF17120.5 CBZ14833.1 - 0.62 9.7 10.6 0.69 9.6 0.1 3.3 4 0 0 4 4 4 0 Zinc-ribbon, C4HC2 type LIM PF00412.22 CBZ14833.1 - 0.77 10.0 5.2 3.2 8.1 0.2 3.1 3 0 0 3 3 3 0 LIM domain zf-rbx1 PF12678.7 CBZ14833.1 - 0.92 9.8 25.5 2.6 8.4 5.6 4.5 3 2 0 3 3 3 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CBZ14833.1 - 9.7 6.3 15.8 2.7 8.1 1.0 4.4 4 2 0 4 4 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-WRNIP1_ubi PF18279.1 CBZ14833.1 - 9.8 7.1 9.2 7.2 7.5 0.3 3.5 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain FixS PF03597.15 CBZ14834.1 - 0.12 12.1 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Ank_4 PF13637.6 CBZ14836.1 - 2.6e-24 85.3 3.1 2.2e-11 44.0 0.1 3.6 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBZ14836.1 - 2.4e-20 72.9 0.2 1.7e-13 50.9 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 CBZ14836.1 - 9.3e-19 67.0 0.6 3.1e-09 36.8 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 CBZ14836.1 - 5.2e-18 63.3 0.3 4.1e-05 23.7 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 CBZ14836.1 - 9.2e-18 64.1 4.1 2.2e-09 37.4 0.1 3.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) GATase_7 PF13537.6 CBZ14836.1 - 0.054 13.4 0.1 0.45 10.4 0.0 2.1 1 1 1 2 2 2 0 Glutamine amidotransferase domain SlyX PF04102.12 CBZ14837.1 - 0.051 14.2 0.6 0.051 14.2 0.6 4.5 4 2 0 4 4 4 0 SlyX Speriolin_N PF15058.6 CBZ14837.1 - 9.6 6.2 12.6 33 4.5 9.9 3.0 2 1 0 2 2 2 0 Speriolin N terminus FYVE PF01363.21 CBZ14846.1 - 4.9e-16 58.6 14.1 3.8e-15 55.8 7.4 2.5 2 0 0 2 2 2 2 FYVE zinc finger C1_1 PF00130.22 CBZ14846.1 - 0.063 13.2 8.6 0.086 12.7 3.7 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.7 CBZ14846.1 - 0.3 11.1 17.2 0.76 9.9 9.5 3.3 1 1 0 2 2 2 0 Double zinc ribbon zf-C3HC4_3 PF13920.6 CBZ14846.1 - 1.4 8.9 21.0 0.18 11.7 0.7 3.1 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) POP1 PF06978.11 CBZ14846.1 - 3.2 7.7 24.5 5.4 7.0 24.5 1.3 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 DUF3584 PF12128.8 CBZ14846.1 - 4 4.8 39.3 4.8 4.5 39.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SRP-alpha_N PF04086.13 CBZ14846.1 - 4.5 7.1 26.7 6.1 6.7 26.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Rhodanese_C PF12368.8 CBZ14846.1 - 5.5 7.4 15.4 7.8 7.0 8.9 2.5 1 1 1 2 2 2 0 Rhodanase C-terminal Asp-B-Hydro_N PF05279.11 CBZ14846.1 - 6.5 6.8 33.7 8.8 6.3 33.7 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Hid1 PF12722.7 CBZ14846.1 - 7.4 4.6 21.1 9.4 4.2 21.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein zf-HIT PF04438.16 CBZ14846.1 - 9.6 6.2 15.3 7.5 6.5 2.5 2.5 2 0 0 2 2 2 0 HIT zinc finger Zn_ribbon_SprT PF17283.2 CBZ14846.1 - 9.8 6.2 14.5 4.4 7.3 6.6 3.1 2 1 0 2 2 2 0 SprT-like zinc ribbon domain DUF4880 PF16220.5 CBZ14849.1 - 1.2 9.1 10.9 0.6 10.0 3.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4880) DEADboxA PF12343.8 CBZ14849.1 - 3.3 8.3 7.5 4.5 7.9 1.2 2.2 1 1 1 2 2 2 0 Cold shock protein DEAD box A Ribonuclease_3 PF00636.26 CBZ14859.1 - 1.5e-05 25.6 0.1 0.0017 19.0 0.0 3.1 3 1 0 3 3 3 1 Ribonuclease III domain PSD4 PF07631.11 CBZ14860.1 - 0.037 14.6 5.9 1.8 9.1 1.7 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1592) DUF3094 PF11293.8 CBZ14860.1 - 0.064 13.0 1.4 1.6 8.5 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) LRR_4 PF12799.7 CBZ14861.1 - 2.6e-16 59.4 7.5 0.0011 19.4 0.1 5.5 3 1 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ14861.1 - 4.1e-12 45.7 9.2 5e-05 23.0 0.2 4.8 4 1 1 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 CBZ14861.1 - 8e-07 28.7 0.5 0.011 15.3 0.0 2.6 1 1 0 2 2 2 2 Leucine-rich repeat LRR_5 PF13306.6 CBZ14861.1 - 0.0017 18.3 0.0 0.0029 17.6 0.0 1.3 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) Pentapeptide_4 PF13599.6 CBZ14862.1 - 1.1e-15 57.5 20.7 5.5e-09 36.1 5.3 2.8 2 1 1 3 3 3 2 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 CBZ14862.1 - 1.4e-11 43.8 12.0 4.1e-06 26.3 1.3 4.2 1 1 1 3 3 3 3 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 CBZ14862.1 - 3.2e-11 43.2 10.5 9.2e-07 28.9 1.5 3.6 1 1 1 3 3 3 3 Pentapeptide repeats (9 copies) Adaptin_N PF01602.20 CBZ14871.1 - 1.3e-78 264.9 0.0 1.6e-78 264.6 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CBZ14871.1 - 2.1e-14 53.9 0.7 4.8e-14 52.7 0.3 1.8 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CBZ14871.1 - 2.7e-06 27.7 6.0 3.7e-05 24.0 2.2 3.9 2 2 2 4 4 4 2 HEAT repeats HEAT PF02985.22 CBZ14871.1 - 1e-05 25.4 3.9 0.31 11.4 0.3 4.4 3 0 0 3 3 3 3 HEAT repeat HEAT_EZ PF13513.6 CBZ14871.1 - 6.4 7.4 6.2 16 6.1 0.7 3.2 1 1 2 3 3 3 0 HEAT-like repeat Exo_endo_phos PF03372.23 CBZ14872.1 - 2.3e-08 33.8 0.0 4.3e-05 23.2 0.0 2.5 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CBZ14872.1 - 0.036 13.9 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Kelch_1 PF01344.25 CBZ14874.1 - 5.2e-08 32.4 0.1 4e-05 23.1 0.1 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_5 PF13854.6 CBZ14874.1 - 0.002 18.0 0.0 0.079 13.0 0.0 2.3 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.15 CBZ14874.1 - 0.005 16.8 0.3 3 8.0 0.2 2.6 2 1 0 2 2 2 2 Kelch motif Kelch_6 PF13964.6 CBZ14874.1 - 0.009 16.3 0.0 1.2 9.6 0.0 2.4 1 1 1 2 2 2 1 Kelch motif Kelch_4 PF13418.6 CBZ14874.1 - 0.025 14.6 0.0 2.8 8.0 0.0 2.4 2 0 0 2 2 2 0 Galactose oxidase, central domain AFG1_ATPase PF03969.16 CBZ14876.1 - 1.6e-53 181.9 2.5 8.7e-53 179.5 0.1 2.4 3 0 0 3 3 3 1 AFG1-like ATPase AAA_16 PF13191.6 CBZ14876.1 - 2.3e-05 24.9 0.4 0.0002 21.8 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CBZ14876.1 - 0.0095 16.2 0.1 0.11 12.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CBZ14876.1 - 0.07 13.5 0.1 4.5 7.6 0.1 2.9 2 1 0 2 2 2 0 AAA domain SET PF00856.28 CBZ14877.1 - 1.3e-05 25.7 0.0 0.00062 20.2 0.0 2.3 1 1 0 1 1 1 1 SET domain Torus PF16131.5 CBZ40905.1 - 0.0088 16.7 2.1 1.7 9.4 0.1 2.6 2 0 0 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 CBZ40905.1 - 1.6 8.9 8.6 0.54 10.4 3.8 2.5 2 0 0 2 2 2 0 Zinc finger domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Kinetoplastida/Leishmania_braziliensis-ASM284v2/GCA_000002845.2_ASM284v2_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Kinetoplastida/Leishmania_braziliensis-ASM284v2/GCA_000002845.2_ASM284v2_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Kinetoplastida/Leishmania_braziliensis-ASM284v2/GCA_000002845.2_ASM284v2_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Kinetoplastida/Leishmania_braziliensis-ASM284v2/GCA_000002845.2_ASM284v2_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 08:33:28 2019 # [ok]