# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DUP PF00674.13 CAR25450.1 - 4.8e-07 29.7 0.3 4.8e-07 29.7 0.2 2.5 2 1 1 3 3 3 1 DUP family Herpes_UL73 PF03554.8 CAR25450.1 - 0.22 11.3 3.2 5.4 6.8 0.3 2.6 2 0 0 2 2 2 0 UL73 viral envelope glycoprotein Git3_C PF11970.3 CAR25451.1 - 0.14 11.9 0.2 0.31 10.8 0.2 1.5 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term DUP PF00674.13 CAR25452.1 - 1.7e-06 27.9 1.3 1.7e-06 27.9 0.9 2.0 2 0 0 2 2 2 1 DUP family DUP PF00674.13 CAR25453.1 - 4.5e-26 90.9 9.9 1.9e-14 53.5 0.7 2.7 2 1 0 2 2 2 2 DUP family DUP PF00674.13 CAR25454.1 - 1.2e-06 28.4 0.4 1.2e-06 28.4 0.3 2.5 2 1 1 3 3 3 1 DUP family DUF4199 PF13858.1 CAR25454.1 - 0.045 13.6 8.4 11 5.9 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) DUF4532 PF15046.1 CAR25454.1 - 0.067 12.1 0.0 0.09 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4532) Aldo_ket_red PF00248.16 CAR25456.1 - 5.5e-61 205.8 0.0 6.2e-61 205.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_97 PF10566.4 CAR25456.1 - 0.08 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycoside hydrolase 97 AA_permease PF00324.16 CAR25457.1 - 1.3e-118 396.3 37.5 1.6e-118 396.1 26.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CAR25457.1 - 3.9e-34 117.9 41.7 4.8e-34 117.6 28.9 1.0 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 CAR25458.1 - 1.9e-43 148.5 41.3 1.8e-42 145.3 28.6 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CAR25458.1 - 5.9e-16 58.0 22.6 4e-15 55.3 7.7 2.6 1 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 CAR25458.1 - 3.6e-06 25.4 12.5 6.6e-06 24.6 8.6 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 CAR25459.1 - 9.3e-22 77.2 12.4 1.4e-21 76.5 8.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily SdpI PF13630.1 CAR25459.1 - 7.6 6.3 10.6 1.6 8.5 0.9 3.3 4 0 0 4 4 4 0 SdpI/YhfL protein family adh_short PF00106.20 CAR25460.1 - 3.6e-31 108.3 0.7 4.6e-31 107.9 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CAR25460.1 - 1.9e-18 67.1 0.1 2.3e-18 66.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CAR25460.1 - 9.2e-14 51.5 1.2 1.3e-13 51.0 0.8 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CAR25460.1 - 2.6e-07 30.3 0.3 4.3e-06 26.3 0.2 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 CAR25460.1 - 5.8e-05 22.1 0.3 7.1e-05 21.8 0.2 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 CAR25460.1 - 0.00075 19.5 1.1 0.0012 18.8 0.8 1.5 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 CAR25460.1 - 0.011 14.4 0.5 0.016 13.9 0.4 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 CAR25460.1 - 0.082 13.3 0.1 0.18 12.2 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Fungal_trans_2 PF11951.3 CAR25461.1 - 6.6e-103 344.2 3.2 1e-102 343.6 2.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR25461.1 - 2.5e-12 46.4 7.4 5.9e-12 45.2 5.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIID-18kDa PF02269.11 CAR25462.1 - 5.5e-33 112.6 0.0 7.8e-33 112.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.19 CAR25462.1 - 0.016 15.3 0.0 0.05 13.7 0.0 1.8 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 TAF PF02969.12 CAR25462.1 - 0.053 13.4 0.0 1 9.3 0.0 2.3 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) Nop14 PF04147.7 CAR25462.1 - 0.32 8.8 10.1 0.33 8.8 7.0 1.2 1 0 0 1 1 1 0 Nop14-like family ERO1 PF04137.10 CAR25463.1 - 4.1e-119 397.7 1.6 6.5e-119 397.1 1.1 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) VPS9 PF02204.13 CAR25464.1 - 8.5e-27 93.2 0.3 1.7e-26 92.2 0.2 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 CAR25464.1 - 2.5e-11 42.8 0.0 5.8e-11 41.6 0.0 1.7 1 0 0 1 1 1 1 CUE domain Sep15_SelM PF08806.6 CAR25464.1 - 0.048 13.4 0.2 0.28 10.9 0.0 2.4 3 0 0 3 3 3 0 Sep15/SelM redox domain Asn_synthase PF00733.16 CAR25465.1 - 6.4e-47 160.1 0.0 9.9e-47 159.5 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 CAR25465.1 - 1.6e-10 40.7 0.4 8.9e-09 35.1 0.2 2.8 2 1 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.1 CAR25465.1 - 1e-05 25.4 0.0 5.2e-05 23.2 0.0 2.2 2 1 0 2 2 2 1 Glutamine amidotransferase domain Cu-oxidase_2 PF07731.9 CAR25465.1 - 0.078 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Multicopper oxidase Rad10 PF03834.9 CAR25466.1 - 2.8e-26 90.9 1.8 4.7e-26 90.2 1.2 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Prefoldin PF02996.12 CAR25467.1 - 2.3e-25 88.5 1.4 2.5e-25 88.4 0.6 1.3 1 1 0 1 1 1 1 Prefoldin subunit CEP19 PF14933.1 CAR25467.1 - 0.013 15.8 3.0 4.7 7.4 0.0 2.2 2 0 0 2 2 2 0 CEP19-like protein ERbeta_N PF12497.3 CAR25467.1 - 0.041 13.7 0.1 0.069 12.9 0.0 1.4 1 1 0 1 1 1 0 Estrogen receptor beta DUF2877 PF11392.3 CAR25467.1 - 0.22 11.7 0.9 5.6 7.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2877) Utp14 PF04615.8 CAR25468.1 - 1.4e-194 648.3 82.9 1.4e-194 648.3 57.4 2.0 1 1 1 2 2 2 1 Utp14 protein Proteasome PF00227.21 CAR25469.1 - 3.1e-60 202.7 0.0 3.7e-60 202.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CAR25469.1 - 3.3e-09 35.8 0.9 5.9e-09 35.0 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RRM_5 PF13893.1 CAR25470.1 - 1.6e-08 34.2 0.0 2.8e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAR25470.1 - 2.8e-05 23.6 0.0 4.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 CAR25470.1 - 0.00013 21.5 1.5 0.00013 21.5 1.1 2.1 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_6 PF14259.1 CAR25470.1 - 0.00074 19.4 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) COX14 PF14880.1 CAR25471.1 - 8e-24 83.0 0.4 8.8e-24 82.8 0.3 1.0 1 0 0 1 1 1 1 Cytochrome oxidase c assembly RebB PF11747.3 CAR25471.1 - 0.022 14.6 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 Killing trait Ish1 PF10281.4 CAR25472.1 - 2.4e-34 117.0 20.1 1.8e-07 31.0 0.0 6.9 6 0 0 6 6 6 6 Putative stress-responsive nuclear envelope protein SAP PF02037.22 CAR25472.1 - 0.0011 18.4 0.0 1.2 8.7 0.0 4.6 5 0 0 5 5 5 1 SAP domain HeH PF12949.2 CAR25472.1 - 0.0037 16.7 1.6 3.4 7.3 0.0 4.5 5 0 0 5 5 5 1 HeH/LEM domain SAP30_Sin3_bdg PF13867.1 CAR25472.1 - 0.0062 16.3 0.4 0.47 10.3 0.1 2.8 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 APC2 PF08672.6 CAR25472.1 - 0.014 15.6 0.1 14 6.0 0.0 4.4 4 0 0 4 4 4 0 Anaphase promoting complex (APC) subunit 2 Remorin_C PF03763.8 CAR25472.1 - 0.099 12.1 3.0 0.14 11.7 0.0 2.6 3 0 0 3 3 3 0 Remorin, C-terminal region DUF148 PF02520.12 CAR25472.1 - 2 8.2 8.3 0.82 9.4 0.8 3.5 4 0 0 4 4 4 0 Domain of unknown function DUF148 RPM2 PF08579.6 CAR25474.1 - 2e-45 153.8 1.3 8.8e-45 151.6 0.9 2.2 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) PPR_3 PF13812.1 CAR25474.1 - 0.045 14.0 0.1 16 6.1 0.0 4.1 3 0 0 3 3 3 0 Pentatricopeptide repeat domain CitMHS PF03600.11 CAR25474.1 - 0.12 10.9 0.0 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 Citrate transporter HMG_CoA_synt_C PF08540.5 CAR25475.1 - 5.7e-109 363.9 3.1 7.2e-109 363.6 2.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 CAR25475.1 - 2.3e-89 297.5 0.2 3.2e-89 297.0 0.2 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal F-box-like PF12937.2 CAR25476.1 - 2.5e-12 46.3 0.8 4.9e-12 45.3 0.6 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CAR25476.1 - 5.4e-08 32.2 0.6 5.4e-08 32.2 0.4 1.9 2 0 0 2 2 2 1 F-box domain UIM PF02809.15 CAR25476.1 - 0.0023 17.3 3.2 0.0023 17.3 2.2 4.8 5 0 0 5 5 5 1 Ubiquitin interaction motif PRANC PF09372.5 CAR25476.1 - 0.0047 16.8 0.2 0.01 15.7 0.1 1.6 1 0 0 1 1 1 1 PRANC domain WD40 PF00400.27 CAR25476.1 - 0.013 15.3 1.5 0.42 10.5 0.7 2.7 2 0 0 2 2 2 0 WD domain, G-beta repeat Zip PF02535.17 CAR25476.1 - 1.9 7.4 3.5 3 6.7 2.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter NAD_binding_1 PF00175.16 CAR25477.1 - 5.1e-25 88.1 0.0 8.3e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CAR25477.1 - 1.9e-23 82.4 0.0 3.1e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 CAR25477.1 - 2.6e-05 24.1 0.0 0.00022 21.1 0.0 2.3 2 1 1 3 3 3 1 Ferric reductase NAD binding domain ALO PF04030.9 CAR25478.1 - 4.3e-99 331.3 1.6 4.3e-99 331.3 1.1 1.5 2 0 0 2 2 2 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 CAR25478.1 - 1.2e-29 102.5 0.0 1.7e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Tubulin PF00091.20 CAR25480.1 - 9.9e-71 237.9 0.0 1.3e-70 237.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CAR25480.1 - 1.9e-49 166.9 0.1 2.9e-49 166.2 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Sugar_tr PF00083.19 CAR25481.1 - 3.4e-41 141.2 16.7 1e-27 96.8 5.2 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CAR25481.1 - 2.7e-20 72.3 21.2 2.4e-17 62.6 9.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TIL PF01826.12 CAR25481.1 - 0.019 15.1 0.4 0.019 15.1 0.2 1.8 2 0 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain SQS_PSY PF00494.14 CAR25482.1 - 3.1e-41 141.4 0.0 4e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase TFIIA_gamma_N PF02268.11 CAR25482.1 - 0.037 13.5 0.1 0.098 12.2 0.1 1.7 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit, helical domain Pept_tRNA_hydro PF01195.14 CAR25483.1 - 1.6e-45 154.8 0.0 1.8e-45 154.7 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Gtr1_RagA PF04670.7 CAR25484.1 - 1.1e-94 315.9 1.7 1.4e-94 315.6 1.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 CAR25484.1 - 1.2e-09 37.7 0.5 3e-09 36.4 0.1 1.8 2 0 0 2 2 2 1 Ras family Miro PF08477.8 CAR25484.1 - 7.1e-08 32.9 0.1 2e-07 31.4 0.1 1.8 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAR25484.1 - 2.6e-07 30.0 0.1 2.6e-07 30.0 0.1 1.9 3 0 0 3 3 3 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CAR25484.1 - 1.4e-06 28.2 0.1 4.6e-06 26.5 0.0 1.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.22 CAR25484.1 - 0.0077 16.5 0.1 0.016 15.4 0.1 1.8 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 CAR25484.1 - 0.012 15.0 0.2 0.025 14.1 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AIG1 PF04548.11 CAR25484.1 - 0.019 14.0 0.7 0.15 11.1 0.0 2.3 1 1 1 2 2 2 0 AIG1 family SopD PF11047.3 CAR25484.1 - 0.07 12.0 4.0 0.029 13.3 0.7 1.7 2 0 0 2 2 2 0 Salmonella outer protein D AAA_10 PF12846.2 CAR25484.1 - 0.13 11.6 0.3 0.24 10.8 0.2 1.4 1 1 0 1 1 1 0 AAA-like domain Guanylate_kin PF00625.16 CAR25484.1 - 0.13 11.6 2.8 1.3 8.4 1.0 2.6 2 1 0 2 2 2 0 Guanylate kinase tRNA-synt_2 PF00152.15 CAR25486.1 - 1.3e-73 247.6 0.0 1.8e-73 247.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 CAR25486.1 - 1e-05 24.8 0.2 7.6e-05 22.0 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 CAR25486.1 - 0.0037 17.0 0.0 0.009 15.8 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Mating_N PF12731.2 CAR25486.1 - 0.045 13.6 0.0 1.3 8.9 0.0 2.7 3 0 0 3 3 3 0 Mating-type protein beta 1 Ferric_reduct PF01794.14 CAR25487.1 - 7.1e-18 64.9 17.9 7.1e-18 64.9 12.4 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 CAR25487.1 - 4.3e-15 55.9 0.1 6.9e-15 55.2 0.1 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 CAR25487.1 - 2.7e-14 52.8 0.1 7.5e-14 51.4 0.0 1.8 2 0 0 2 2 2 1 FAD-binding domain RNase_HII PF01351.13 CAR25488.1 - 7.5e-60 201.9 0.0 9.1e-60 201.6 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII 2-Hacid_dh_C PF02826.14 CAR25489.1 - 2e-31 108.5 0.0 7.9e-31 106.5 0.0 1.9 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 CAR25489.1 - 0.00017 21.4 0.0 0.00038 20.3 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 CAR25489.1 - 0.0076 16.3 0.1 0.043 13.9 0.1 2.1 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 CAR25489.1 - 0.01 16.2 0.1 0.038 14.4 0.0 2.1 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 CAR25489.1 - 0.02 15.1 0.0 0.057 13.6 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.13 CAR25489.1 - 0.028 14.3 0.0 0.074 13.0 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain ThiF PF00899.16 CAR25489.1 - 0.046 13.5 0.0 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 ThiF family 2-oxoacid_dh PF00198.18 CAR25490.1 - 2.4e-72 242.9 0.2 3.1e-72 242.5 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CAR25490.1 - 2e-16 59.3 0.2 4.4e-16 58.2 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 CAR25490.1 - 1.1e-14 53.8 0.6 2.6e-14 52.5 0.2 1.9 2 0 0 2 2 2 1 e3 binding domain Tom7 PF08038.7 CAR25491.1 - 4.8e-20 70.7 0.2 6.2e-20 70.3 0.1 1.1 1 0 0 1 1 1 1 TOM7 family Mito_carr PF00153.22 CAR25492.1 - 6.2e-60 198.9 2.8 5.7e-21 74.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L13 PF00572.13 CAR25493.1 - 1.3e-24 86.7 0.1 1.3e-24 86.7 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L13 Fork_head PF00250.13 CAR25495.1 - 1.3e-36 124.4 0.3 2.8e-36 123.4 0.2 1.5 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 CAR25495.1 - 9.5e-10 38.4 0.0 2.4e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 FHA domain SBBP PF06739.6 CAR25495.1 - 0.033 13.9 0.0 0.083 12.6 0.0 1.7 1 0 0 1 1 1 0 Beta-propeller repeat MOR2-PAG1_N PF14222.1 CAR25496.1 - 4.5e-190 633.0 8.7 4.5e-190 633.0 6.0 2.7 2 0 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 CAR25496.1 - 2.8e-94 315.7 1.3 2.8e-94 315.7 0.9 3.0 4 0 0 4 4 4 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 CAR25496.1 - 2.6e-21 75.0 11.1 5.3e-09 34.2 0.1 3.4 3 0 0 3 3 3 3 Cell morphogenesis central region Ribosomal_60s PF00428.14 CAR25496.1 - 0.58 10.5 5.9 1.4 9.3 3.3 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein MMS19_N PF14500.1 CAR25497.1 - 9.1e-96 320.1 8.4 1.8e-93 312.6 0.1 4.0 4 1 2 6 6 6 3 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 CAR25497.1 - 2.2e-92 309.9 18.7 2.2e-92 309.9 12.9 2.8 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal Xpo1 PF08389.7 CAR25497.1 - 5.3e-05 23.1 12.0 0.012 15.5 0.6 4.2 4 1 1 5 5 5 2 Exportin 1-like protein HEAT_2 PF13646.1 CAR25497.1 - 0.00034 20.8 0.0 3.8 7.8 0.0 4.7 3 2 2 5 5 5 1 HEAT repeats HEAT PF02985.17 CAR25497.1 - 0.002 18.0 0.2 0.18 11.9 0.0 4.3 4 0 0 4 4 4 1 HEAT repeat Vac14_Fab1_bd PF12755.2 CAR25497.1 - 0.003 17.9 2.4 0.12 12.7 0.0 4.1 3 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CAR25497.1 - 0.028 14.9 0.2 8.9 6.9 0.0 4.0 4 0 0 4 4 4 0 HEAT-like repeat SNF2_N PF00176.18 CAR25499.1 - 6.7e-84 281.1 0.2 6.7e-84 281.1 0.2 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CAR25499.1 - 5.9e-21 74.1 0.3 1.3e-17 63.3 0.0 4.1 3 0 0 3 3 3 2 Helicase conserved C-terminal domain Bromodomain PF00439.20 CAR25499.1 - 3e-20 71.9 0.2 3e-20 71.9 0.2 2.4 2 0 0 2 2 2 1 Bromodomain SnAC PF14619.1 CAR25499.1 - 5.1e-15 55.3 0.2 5.1e-15 55.3 0.2 5.1 4 1 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex Ribosomal_L6 PF00347.18 CAR25500.1 - 6e-26 90.7 7.1 3e-13 50.0 0.6 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 PC4 PF02229.11 CAR25500.1 - 0.038 13.2 0.8 0.069 12.3 0.1 1.8 2 0 0 2 2 2 0 Transcriptional Coactivator p15 (PC4) Transket_pyr PF02779.19 CAR25501.1 - 2.1e-66 222.7 0.0 4.7e-66 221.6 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 CAR25501.1 - 3.4e-54 183.6 0.0 4.8e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Pga1 PF10333.4 CAR25501.1 - 0.095 12.3 0.1 0.5 10.0 0.0 2.1 3 0 0 3 3 3 0 GPI-Mannosyltransferase II co-activator adh_short PF00106.20 CAR25502.1 - 1.8e-26 93.0 0.1 2.5e-26 92.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CAR25502.1 - 1.7e-13 50.8 0.0 2.5e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CAR25502.1 - 1.6e-09 37.6 0.1 2.5e-09 37.0 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CAR25502.1 - 2.6e-06 27.0 0.9 1.3e-05 24.7 0.6 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CAR25502.1 - 0.00022 21.3 0.0 0.00046 20.2 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 CAR25502.1 - 0.00027 20.1 0.2 0.0092 15.1 0.2 2.7 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.12 CAR25502.1 - 0.0069 15.3 0.0 0.0098 14.8 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 CAR25502.1 - 0.017 14.8 0.4 0.037 13.8 0.3 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Cas_Cas1 PF01867.11 CAR25502.1 - 0.039 13.0 0.1 0.31 10.0 0.0 2.0 2 0 0 2 2 2 0 CRISPR associated protein Cas1 NmrA PF05368.8 CAR25502.1 - 0.046 12.9 0.0 0.081 12.1 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family SUN PF03856.8 CAR25503.1 - 5.1e-105 350.2 17.4 1.3e-104 348.8 12.1 1.7 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) MFS_1 PF07690.11 CAR25505.1 - 7.5e-43 146.5 26.1 1.5e-39 135.7 8.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CAR25505.1 - 9.1e-11 40.9 13.2 9.1e-11 40.9 9.1 2.8 2 1 1 3 3 3 3 Sugar (and other) transporter TRI12 PF06609.8 CAR25505.1 - 0.0034 15.6 4.6 0.0055 14.9 3.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DnaJ PF00226.26 CAR25506.1 - 7.8e-26 89.6 2.2 1.3e-25 88.9 1.5 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CAR25506.1 - 1.4e-19 69.7 2.7 2.9e-17 62.3 0.0 2.7 3 1 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CAR25506.1 - 5.1e-15 55.2 17.3 8e-15 54.6 12.0 1.3 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 CAR25506.1 - 0.18 11.4 10.1 1.6 8.4 1.0 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Methyltransf_26 PF13659.1 CAR25507.1 - 3.6e-11 43.1 0.0 4.2e-10 39.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CAR25507.1 - 1.8e-09 37.2 0.0 3.7e-09 36.1 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.2 CAR25507.1 - 5.5e-08 33.3 0.0 1.8e-07 31.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAR25507.1 - 8.3e-08 31.9 0.0 1.3e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAR25507.1 - 6.3e-05 23.2 0.0 0.00011 22.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CAR25507.1 - 0.089 13.2 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 CAR25507.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Gcd10p PF04189.8 CAR25508.1 - 1.1e-97 326.8 1.1 1.4e-97 326.5 0.7 1.1 1 0 0 1 1 1 1 Gcd10p family DUF1987 PF09345.5 CAR25508.1 - 0.055 13.2 1.0 0.26 11.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1987) Nol1_Nop2_Fmu PF01189.12 CAR25509.1 - 2.6e-106 355.1 0.0 5.4e-106 354.0 0.0 1.6 2 0 0 2 2 2 1 NOL1/NOP2/sun family FtsJ PF01728.14 CAR25509.1 - 0.0033 17.4 0.0 0.0084 16.1 0.0 1.7 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 CAR25509.1 - 0.0034 16.9 0.0 0.0075 15.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Actin PF00022.14 CAR25510.1 - 1.8e-52 178.1 0.0 3.4e-50 170.5 0.0 2.5 1 1 0 1 1 1 1 Actin Ras PF00071.17 CAR25511.1 - 1.2e-55 187.3 0.0 1.7e-55 186.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR25511.1 - 2.6e-17 63.3 0.0 4.5e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAR25511.1 - 3.8e-09 36.0 0.0 6.2e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CAR25511.1 - 0.00055 19.1 0.0 0.00062 18.9 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CAR25511.1 - 0.0008 18.6 0.0 0.0016 17.7 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 CAR25511.1 - 0.00082 18.8 0.1 0.0079 15.6 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CAR25511.1 - 0.0013 18.6 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 CAR25511.1 - 0.0018 17.0 0.1 0.0081 14.8 0.1 1.8 1 1 1 2 2 2 1 G-protein alpha subunit ABC_tran PF00005.22 CAR25511.1 - 0.032 14.5 0.0 0.1 12.9 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Arch_ATPase PF01637.13 CAR25511.1 - 0.044 13.4 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Herpes_gE PF02480.11 CAR25512.1 - 0.021 13.1 0.0 0.034 12.4 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Y_phosphatase2 PF03162.8 CAR25513.1 - 4.1e-49 166.1 0.0 4.8e-49 165.8 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 CAR25513.1 - 2.6e-06 27.7 0.0 3.6e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Aminotran_1_2 PF00155.16 CAR25514.1 - 2.3e-64 217.6 0.0 2.6e-64 217.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.8 CAR25514.1 - 0.00021 20.0 0.0 0.0003 19.5 0.0 1.1 1 0 0 1 1 1 1 Allinase Cys_Met_Meta_PP PF01053.15 CAR25514.1 - 0.062 11.5 0.0 0.11 10.7 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Porin_3 PF01459.17 CAR25516.1 - 2.5e-56 190.9 1.0 2.8e-56 190.8 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic porin Vac7 PF12751.2 CAR25517.1 - 9.9e-24 83.8 0.6 8.8e-16 57.7 0.0 3.4 3 0 0 3 3 3 2 Vacuolar segregation subunit 7 DSPc PF00782.15 CAR25518.1 - 4.4e-34 116.9 0.0 6.5e-34 116.3 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 CAR25518.1 - 0.0062 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 CAR25518.1 - 0.082 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase tRNA_SAD PF07973.9 CAR25519.1 - 1.8e-08 34.1 0.1 3.8e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.14 CAR25519.1 - 1.9e-06 26.5 0.0 2.9e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) WD40 PF00400.27 CAR25520.1 - 3e-10 39.5 2.4 5.2e-05 22.9 0.1 4.2 5 0 0 5 5 5 2 WD domain, G-beta repeat Pkinase PF00069.20 CAR25521.1 - 1.2e-37 129.4 0.0 2.2e-37 128.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR25521.1 - 1.1e-27 96.8 0.0 1.6e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR25521.1 - 0.0019 17.2 0.0 0.0039 16.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CAR25521.1 - 0.034 13.8 0.0 0.1 12.3 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Hist_deacetyl PF00850.14 CAR25522.1 - 9.7e-95 317.4 0.0 1.3e-94 317.0 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 CAR25522.1 - 3.8e-51 173.0 0.1 5.4e-51 172.5 0.1 1.2 1 0 0 1 1 1 1 Arb2 domain Nol1_Nop2_Fmu PF01189.12 CAR25523.1 - 1.5e-20 73.7 0.0 2.7e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 CAR25523.1 - 0.002 18.1 0.1 0.0048 16.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain DUF4145 PF13643.1 CAR25523.1 - 0.11 12.3 0.6 11 5.9 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4145) Iso_dh PF00180.15 CAR25524.1 - 2.4e-107 358.9 0.0 2.9e-107 358.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase R3H PF01424.17 CAR25525.1 - 1.7e-14 53.2 0.1 2.8e-14 52.5 0.1 1.4 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 CAR25525.1 - 6.3e-06 26.0 36.1 3.8e-05 23.5 11.4 12.1 13 0 0 13 13 13 6 NF-X1 type zinc finger MRP-S25 PF13741.1 CAR25526.1 - 1.3e-91 306.2 3.9 1.5e-91 305.9 2.7 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.4 CAR25526.1 - 3.1e-05 23.8 0.3 0.00021 21.2 0.1 2.2 1 1 1 2 2 2 1 Mitochondrial ribosomal protein S23 DUF1242 PF06842.7 CAR25527.1 - 1.4e-16 59.7 0.9 1.8e-16 59.3 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) DUF4141 PF13605.1 CAR25527.1 - 0.3 10.2 0.2 0.3 10.2 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4141) DUF1253 PF06862.7 CAR25528.1 - 3.1e-156 520.2 4.4 4.7e-156 519.6 3.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) DEAD PF00270.24 CAR25528.1 - 0.0045 16.5 0.1 0.064 12.7 0.1 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase ICE2 PF08426.5 CAR25529.1 - 4.5e-159 529.5 32.2 5.2e-159 529.2 22.3 1.0 1 0 0 1 1 1 1 ICE2 Cyclin_N PF00134.18 CAR25530.1 - 2.1e-18 66.1 1.1 1.3e-17 63.5 0.2 2.3 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CAR25530.1 - 0.0019 18.1 3.0 0.05 13.5 0.6 2.7 2 1 0 2 2 2 2 Cyclin, C-terminal domain Aa_trans PF01490.13 CAR25531.1 - 1.3e-112 376.2 18.3 1.5e-112 376.0 12.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Y_phosphatase2 PF03162.8 CAR25532.1 - 1.6e-62 209.7 0.0 1.8e-62 209.5 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 CAR25532.1 - 3.5e-08 33.8 0.0 4.9e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 CAR25532.1 - 0.0014 18.0 0.0 0.0018 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 CAR25532.1 - 0.0014 18.2 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF2416 PF10315.4 CAR25533.1 - 1.3e-36 125.0 0.5 1.7e-36 124.7 0.4 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2416) Histone PF00125.19 CAR25534.1 - 5.2e-30 103.3 0.7 8.5e-30 102.7 0.5 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CAR25534.1 - 9.4e-07 28.9 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CAR25534.1 - 0.002 18.1 1.0 0.0025 17.8 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CAR25534.1 - 0.058 13.1 0.1 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 CAR25535.1 - 2.3e-15 56.4 0.3 2.8e-15 56.2 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CAR25535.1 - 1.6e-05 24.8 0.1 2.8e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 CAR25535.1 - 3.7e-05 23.5 0.2 5.2e-05 23.1 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 CAR25535.1 - 4.8e-05 23.4 0.1 6.6e-05 23.0 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 CAR25535.1 - 0.0013 18.1 0.0 0.0013 18.0 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CAR25535.1 - 0.0058 16.3 0.1 0.0072 16.0 0.0 1.3 1 1 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 CAR25535.1 - 0.04 14.1 0.0 0.067 13.4 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.10 CAR25535.1 - 0.13 11.9 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Glyco_transf_15 PF01793.11 CAR25536.1 - 1.3e-120 402.2 12.7 1.8e-120 401.8 8.8 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Sds3 PF08598.6 CAR25537.1 - 6.1e-59 198.9 7.1 1.5e-58 197.7 4.9 1.6 1 1 0 1 1 1 1 Sds3-like Secretin_N_2 PF07655.8 CAR25537.1 - 8.2 6.8 9.6 2.5 8.5 1.2 2.6 2 0 0 2 2 2 0 Secretin N-terminal domain Met_10 PF02475.11 CAR25538.1 - 3.2e-10 39.9 0.0 6.1e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.10 CAR25538.1 - 2.6e-06 26.9 0.0 5.6e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_26 PF13659.1 CAR25538.1 - 0.00095 19.1 0.0 0.002 18.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CAR25538.1 - 0.0033 16.8 0.0 0.0066 15.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain zf-H2C2_2 PF13465.1 CAR25539.1 - 8.3e-15 54.2 11.3 2.1e-09 37.1 0.3 4.0 4 1 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 CAR25539.1 - 4e-14 51.9 11.2 4.9e-07 29.7 0.8 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CAR25539.1 - 2.1e-12 46.4 9.2 2.6e-05 24.2 0.7 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CAR25539.1 - 2.6e-07 30.5 4.9 0.0012 18.9 0.1 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CAR25539.1 - 1.3e-06 28.3 2.4 0.00038 20.5 0.1 2.9 3 0 0 3 3 3 2 Zinc-finger of C2H2 type Zn_ribbon_recom PF13408.1 CAR25539.1 - 0.00058 20.0 2.2 0.00058 20.0 1.5 2.3 2 0 0 2 2 2 1 Recombinase zinc beta ribbon domain zf-C2H2_6 PF13912.1 CAR25539.1 - 0.035 14.0 5.5 2.5 8.1 0.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger Zn_Tnp_IS1595 PF12760.2 CAR25539.1 - 0.043 13.6 1.2 0.1 12.4 0.8 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain FYVE PF01363.16 CAR25539.1 - 0.27 11.1 5.4 0.79 9.6 3.8 1.8 1 0 0 1 1 1 0 FYVE zinc finger zf-BED PF02892.10 CAR25539.1 - 0.33 10.7 6.4 0.91 9.3 0.4 3.3 2 1 1 3 3 3 0 BED zinc finger Elf1 PF05129.8 CAR25539.1 - 0.57 9.9 4.9 0.21 11.2 0.5 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like V_ATPase_I PF01496.14 CAR25539.1 - 0.9 7.3 2.5 1.3 6.7 1.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-C2HC_2 PF13913.1 CAR25539.1 - 6.6 6.5 11.4 7.5 6.3 0.1 3.3 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Bac_surface_Ag PF01103.18 CAR25540.1 - 2.6e-39 135.5 4.6 4.4e-39 134.8 3.2 1.4 1 0 0 1 1 1 1 Surface antigen DFP PF04127.10 CAR25541.1 - 2.8e-15 56.4 0.0 2.2e-06 27.4 0.0 2.8 2 1 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein RRM_1 PF00076.17 CAR25542.1 - 2.5e-53 177.6 0.4 3.1e-19 68.3 0.2 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR25542.1 - 7e-30 102.8 0.2 2.4e-10 40.2 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR25542.1 - 3.9e-26 90.6 1.4 3e-08 33.3 0.3 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CAR25542.1 - 0.00047 19.8 0.1 0.042 13.6 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DUF3421 PF11901.3 CAR25542.1 - 0.02 14.6 0.1 6.6 6.4 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3421) Cas_Cas2CT1978 PF09707.5 CAR25542.1 - 0.037 13.9 0.1 4.3 7.3 0.0 2.4 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) UCH PF00443.24 CAR25543.1 - 2.7e-48 164.4 0.4 4.2e-48 163.8 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CAR25543.1 - 5.2e-15 55.6 0.1 1.4e-06 28.0 0.0 3.8 3 1 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase DUF1528 PF07515.6 CAR25543.1 - 0.019 14.9 0.4 0.068 13.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1528) Cytomega_UL20A PF05984.7 CAR25544.1 - 0.13 12.4 0.5 0.17 12.0 0.4 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein Frataxin_Cyay PF01491.11 CAR25545.1 - 7.7e-34 115.7 0.0 9.2e-34 115.5 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Glyco_hydro_38 PF01074.17 CAR25546.1 - 1.4e-82 277.0 1.0 2.4e-82 276.2 0.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 CAR25546.1 - 7.8e-65 219.4 1.2 1.1e-64 218.9 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 CAR25546.1 - 4.8e-24 84.3 0.0 1.8e-23 82.5 0.0 2.1 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Prenyltrans PF00432.16 CAR25547.1 - 3.7e-32 109.5 0.2 1.9e-07 30.4 0.0 6.1 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CAR25547.1 - 3.6e-19 69.2 0.0 2.1e-06 28.0 0.0 3.4 2 1 1 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 CAR25547.1 - 1.7e-06 27.9 0.0 0.0018 18.2 0.0 2.5 2 0 0 2 2 2 2 Prenyltransferase-like Mito_carr PF00153.22 CAR25548.1 - 1.8e-50 168.5 3.7 6e-19 67.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tn7_Tnp_TnsA_C PF08721.6 CAR25548.1 - 0.14 12.1 0.1 4.2 7.4 0.0 2.5 2 0 0 2 2 2 0 TnsA endonuclease C terminal ACPS PF01648.15 CAR25549.1 - 6.4e-10 38.8 0.0 1.2e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Pex14_N PF04695.8 CAR25550.1 - 2.2e-36 124.9 1.1 2.2e-36 124.9 0.8 3.8 3 2 1 4 4 4 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4216 PF13952.1 CAR25550.1 - 0.1 12.1 0.3 1.8 8.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4216) Med5 PF08689.5 CAR25551.1 - 1.3e-253 844.1 45.0 1.4e-253 843.9 31.2 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 SNF2_N PF00176.18 CAR25552.1 - 1.1e-71 241.1 1.7 1.1e-71 241.1 1.2 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.1 CAR25552.1 - 8.9e-53 178.0 22.3 8.9e-53 178.0 15.4 3.2 3 0 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.26 CAR25552.1 - 1e-13 50.9 0.2 6e-13 48.4 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chorismate_synt PF01264.16 CAR25553.1 - 5.1e-133 442.8 0.1 5.8e-133 442.6 0.1 1.0 1 0 0 1 1 1 1 Chorismate synthase SH3_9 PF14604.1 CAR25554.1 - 1.3e-06 27.8 0.1 2.8e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CAR25554.1 - 1e-05 24.8 0.2 4.1e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 CAR25554.1 - 7.6e-05 22.1 0.1 0.00016 21.0 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain Transglut_core PF01841.14 CAR25554.1 - 9.7e-05 22.5 0.0 0.00021 21.4 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Nup84_Nup100 PF04121.8 CAR25555.1 - 4.9e-214 712.0 15.0 5.7e-214 711.8 10.4 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 SUV3_C PF12513.3 CAR25556.1 - 7.6e-15 54.0 2.4 2.5e-14 52.4 1.7 2.0 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 CAR25556.1 - 3e-13 49.4 0.0 7.7e-13 48.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_14 PF13173.1 CAR25556.1 - 0.1 12.4 0.4 1.9 8.3 0.0 2.9 2 1 0 2 2 2 0 AAA domain Thiolase_N PF00108.18 CAR25557.1 - 3.1e-100 334.5 0.7 3.9e-100 334.1 0.5 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CAR25557.1 - 4.3e-45 152.0 3.2 4.6e-45 152.0 0.1 2.4 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CAR25557.1 - 7.1e-05 22.4 2.2 8.2e-05 22.2 0.5 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain APS_kinase PF01583.15 CAR25558.1 - 1.5e-09 37.6 0.0 1.9e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_18 PF13238.1 CAR25558.1 - 6.8e-07 29.6 0.0 1.3e-06 28.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CAR25558.1 - 1e-06 29.5 0.0 1.3e-06 29.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 CAR25558.1 - 3.4e-06 27.0 0.0 4.3e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase DUF258 PF03193.11 CAR25558.1 - 0.0008 18.6 0.0 0.0021 17.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 CAR25558.1 - 0.0019 18.4 0.0 0.0024 18.1 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_33 PF13671.1 CAR25558.1 - 0.0066 16.3 0.0 0.01 15.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 CAR25558.1 - 0.0089 14.9 0.0 0.51 9.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA PF00004.24 CAR25558.1 - 0.012 15.7 0.0 0.2 11.8 0.0 2.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 CAR25558.1 - 0.013 15.2 0.1 0.022 14.5 0.1 1.4 1 0 0 1 1 1 0 Part of AAA domain Zeta_toxin PF06414.7 CAR25558.1 - 0.017 14.2 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.1 CAR25558.1 - 0.022 14.8 0.0 0.038 14.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 CAR25558.1 - 0.031 13.2 0.0 0.26 10.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 CAR25558.1 - 0.032 13.1 0.0 0.076 11.9 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein Guanylate_kin PF00625.16 CAR25558.1 - 0.038 13.4 0.0 0.26 10.7 0.0 2.1 2 1 0 2 2 2 0 Guanylate kinase AAA_28 PF13521.1 CAR25558.1 - 0.042 13.8 0.3 0.083 12.8 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 CAR25558.1 - 0.049 13.1 0.2 0.091 12.3 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 CAR25558.1 - 0.05 13.5 0.0 0.17 11.7 0.0 1.9 2 1 1 3 3 3 0 AAA domain Rad17 PF03215.10 CAR25558.1 - 0.055 12.1 0.0 0.12 11.0 0.0 1.6 1 1 1 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_30 PF13604.1 CAR25558.1 - 0.058 12.9 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 CAR25558.1 - 0.079 13.0 0.0 0.12 12.4 0.0 1.5 1 1 0 1 1 1 0 Sigma-54 interaction domain TrwB_AAD_bind PF10412.4 CAR25558.1 - 0.11 11.1 0.0 0.2 10.2 0.0 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.17 CAR25558.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase MobB PF03205.9 CAR25558.1 - 0.13 11.9 0.2 0.37 10.4 0.0 1.9 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Pkinase PF00069.20 CAR25559.1 - 1.1e-50 172.2 0.6 2.7e-49 167.6 0.4 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR25559.1 - 4.3e-25 88.2 0.7 1.4e-22 79.9 0.1 2.4 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 CAR25559.1 - 1.6e-08 33.8 0.0 2.4e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 CAR25559.1 - 0.011 15.3 1.3 0.017 14.7 0.3 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase APH PF01636.18 CAR25559.1 - 0.014 15.1 0.1 0.022 14.5 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sybindin PF04099.7 CAR25560.1 - 1e-34 119.2 4.9 7.3e-22 77.6 1.6 3.0 2 1 0 2 2 2 2 Sybindin-like family Sedlin_N PF04628.8 CAR25560.1 - 2.6e-10 40.2 0.4 1.9e-09 37.4 0.1 1.9 2 0 0 2 2 2 1 Sedlin, N-terminal conserved region MTHFR PF02219.12 CAR25562.1 - 1.2e-107 359.3 0.0 2.2e-107 358.4 0.0 1.4 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase ERCC4 PF02732.10 CAR25563.1 - 1.7e-26 92.6 0.0 6.5e-26 90.8 0.0 2.1 1 0 0 1 1 1 1 ERCC4 domain ARID PF01388.16 CAR25564.1 - 4.4e-22 77.7 0.2 4.4e-22 77.7 0.1 3.2 4 0 0 4 4 4 1 ARID/BRIGHT DNA binding domain Mitofilin PF09731.4 CAR25564.1 - 0.25 9.9 53.0 0.14 10.7 18.0 2.3 2 0 0 2 2 2 0 Mitochondrial inner membrane protein CAF-1_p150 PF11600.3 CAR25564.1 - 0.98 8.7 50.6 0.049 13.0 23.1 2.4 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Glyco_transf_34 PF05637.7 CAR25565.1 - 1.4e-74 250.6 0.4 1.8e-74 250.2 0.3 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 CAR25565.1 - 0.002 17.4 0.0 0.23 10.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF273 TPR_11 PF13414.1 CAR25566.1 - 1.6e-22 78.9 12.7 1e-09 37.8 0.7 4.3 2 2 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 CAR25566.1 - 4.7e-18 63.9 1.1 3.8e-06 26.2 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 CAR25566.1 - 4.8e-17 60.4 1.7 0.00028 20.5 0.0 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 CAR25566.1 - 7.9e-13 47.5 0.5 0.076 13.2 0.0 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 CAR25566.1 - 1.9e-12 46.6 0.5 0.0058 17.1 0.2 5.5 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 CAR25566.1 - 1.2e-10 41.5 4.3 0.0026 18.0 0.8 4.3 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 CAR25566.1 - 1.3e-10 41.6 2.1 0.0017 18.9 0.4 3.8 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_20 PF14561.1 CAR25566.1 - 6.3e-07 29.4 7.2 0.013 15.6 0.0 4.6 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 CAR25566.1 - 1.2e-06 28.2 4.4 0.00096 19.0 0.8 3.6 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 CAR25566.1 - 8.4e-05 22.0 3.4 1.8 8.5 0.0 5.2 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 CAR25566.1 - 9.2e-05 22.2 0.1 0.018 14.9 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 CAR25566.1 - 0.00019 21.5 2.2 0.015 15.4 0.2 2.7 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 CAR25566.1 - 0.011 15.4 0.7 1 9.3 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DEAD PF00270.24 CAR25567.1 - 2.6e-45 153.9 0.7 1.4e-41 141.8 0.1 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR25567.1 - 1.2e-25 89.1 0.3 3e-25 87.8 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAR25567.1 - 0.00045 20.1 0.1 0.0021 17.9 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 CAR25567.1 - 0.0015 17.7 0.1 0.0045 16.0 0.0 1.8 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit RNA_pol_Rpb1_4 PF05000.12 CAR25567.1 - 0.11 12.1 0.8 0.31 10.8 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 4 RRM_5 PF13893.1 CAR25568.1 - 0.0015 18.3 0.2 0.0029 17.3 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAR25568.1 - 0.0053 16.3 0.1 0.012 15.2 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CAR25568.1 - 0.0067 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif PRP1_N PF06424.7 CAR25569.1 - 1.2e-29 103.2 0.9 1.2e-29 103.2 0.6 2.1 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_16 PF13432.1 CAR25569.1 - 3e-19 69.1 0.6 0.00012 22.5 0.2 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 CAR25569.1 - 8.3e-18 64.4 13.2 0.0003 21.0 0.7 7.9 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 CAR25569.1 - 2.8e-17 61.6 10.4 0.15 12.7 0.1 10.8 6 3 5 11 11 11 6 Tetratricopeptide repeat TPR_11 PF13414.1 CAR25569.1 - 4.6e-17 61.4 2.0 1e-05 25.0 0.0 5.8 5 0 0 5 5 5 3 TPR repeat TPR_2 PF07719.12 CAR25569.1 - 2.4e-12 45.7 8.3 0.1 12.5 0.0 7.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 CAR25569.1 - 3.6e-08 32.6 1.1 0.03 14.1 0.0 6.7 8 1 1 9 9 7 1 Tetratricopeptide repeat TPR_1 PF00515.23 CAR25569.1 - 5.8e-07 28.8 2.7 0.095 12.3 0.0 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 CAR25569.1 - 8e-07 28.9 10.7 0.35 10.8 0.0 7.1 6 3 2 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 CAR25569.1 - 3.5e-06 26.7 3.2 1.3 9.4 0.0 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 CAR25569.1 - 7.7e-05 22.7 8.4 0.078 13.1 0.0 5.6 6 1 0 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CAR25569.1 - 0.0001 22.5 13.2 1.1 9.9 0.0 7.7 10 0 0 10 10 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 CAR25569.1 - 0.0062 16.3 1.8 1 9.2 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat ChAPs PF09295.5 CAR25569.1 - 0.046 12.4 4.3 0.2 10.3 0.1 2.6 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_7 PF13176.1 CAR25569.1 - 0.1 12.4 5.1 31 4.6 0.1 5.2 6 0 0 6 6 4 0 Tetratricopeptide repeat SapB_1 PF05184.10 CAR25569.1 - 0.3 10.9 2.2 0.64 9.9 0.0 2.9 3 0 0 3 3 3 0 Saposin-like type B, region 1 Fungal_trans_2 PF11951.3 CAR25570.1 - 3.7e-24 85.0 0.3 5e-24 84.6 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR25570.1 - 2.9e-07 30.2 12.4 5.1e-07 29.5 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Arginase PF00491.16 CAR25571.1 - 4.2e-81 272.2 0.0 5.1e-81 271.9 0.0 1.1 1 0 0 1 1 1 1 Arginase family MatE PF01554.13 CAR25572.1 - 1.5e-51 174.2 25.5 7.2e-33 113.4 7.7 2.5 2 0 0 2 2 2 2 MatE FMN_red PF03358.10 CAR25573.1 - 1.2e-09 37.9 0.0 1.4e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase SGL PF08450.7 CAR25574.1 - 5.8e-40 137.2 0.0 7.8e-40 136.7 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Bac_rhodopsin PF01036.13 CAR25575.1 - 3.1e-36 124.7 22.1 4e-36 124.4 15.3 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein FMN_red PF03358.10 CAR25576.1 - 3.2e-09 36.4 0.0 4.3e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 CAR25576.1 - 1.6e-05 24.9 0.3 5.9e-05 23.0 0.1 2.0 2 1 0 2 2 2 1 Flavodoxin Flavodoxin_2 PF02525.12 CAR25576.1 - 0.002 17.6 0.0 0.0024 17.3 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold CHCH PF06747.8 CAR25577.1 - 5.7e-08 32.4 12.7 0.00097 18.9 3.0 2.3 2 0 0 2 2 2 2 CHCH domain Cmc1 PF08583.5 CAR25577.1 - 3.6e-05 23.4 10.0 3.6e-05 23.4 0.8 2.3 1 1 1 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.7 CAR25577.1 - 6.9e-05 22.6 7.6 0.021 14.6 0.4 3.1 1 1 3 4 4 4 2 Uncharacterised protein family (UPF0203) Pet191_N PF10203.4 CAR25577.1 - 0.0067 16.4 11.1 0.013 15.5 4.8 2.8 1 1 1 2 2 2 1 Cytochrome c oxidase assembly protein PET191 GCK PF07802.6 CAR25577.1 - 0.03 14.4 9.6 1.7 8.7 0.7 2.8 1 1 2 3 3 3 0 GCK domain COX6B PF02297.12 CAR25577.1 - 0.12 12.3 9.9 0.39 10.7 4.9 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb DB PF01682.14 CAR25577.1 - 0.22 11.5 10.2 0.72 9.9 7.0 1.9 1 1 0 1 1 1 0 DB module DUF1397 PF07165.6 CAR25577.1 - 0.26 10.4 7.9 0.43 9.7 5.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1397) COX17 PF05051.8 CAR25577.1 - 0.43 10.6 7.5 1.5 8.8 0.8 3.2 1 1 1 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) fn2 PF00040.14 CAR25577.1 - 0.96 9.5 5.0 5 7.2 0.1 3.3 2 2 1 3 3 3 0 Fibronectin type II domain NDUF_B7 PF05676.8 CAR25577.1 - 9.6 5.7 8.6 13 5.3 4.1 2.3 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) WD40 PF00400.27 CAR25578.1 - 1.2e-19 69.3 6.9 1.5e-05 24.6 0.1 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat DUF1752 PF08550.5 CAR25579.1 - 3.5e-09 36.0 2.0 7.6e-09 35.0 1.4 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Myb_DNA-binding PF00249.26 CAR25581.1 - 1.2e-17 63.6 13.1 1.5e-09 37.7 0.2 4.4 3 1 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CAR25581.1 - 3.6e-17 62.2 16.5 8.1e-15 54.6 0.7 4.4 4 0 0 4 4 4 2 Myb-like DNA-binding domain DUF3144 PF11342.3 CAR25581.1 - 0.048 13.7 0.3 0.25 11.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3144) MADF_DNA_bdg PF10545.4 CAR25581.1 - 0.058 13.5 0.5 0.058 13.5 0.4 3.8 3 1 1 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.1 CAR25581.1 - 3.4 7.8 20.6 1 9.5 5.0 4.9 3 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain Ribosomal_S17 PF00366.15 CAR25582.1 - 2e-28 98.2 4.5 3.1e-28 97.5 3.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 ADH_zinc_N PF00107.21 CAR25584.1 - 9.9e-29 99.5 0.0 1.6e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CAR25584.1 - 1.4e-16 61.5 0.0 8.4e-16 59.0 0.0 2.2 1 1 2 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CAR25584.1 - 1e-09 38.1 0.0 1.9e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.19 CAR25584.1 - 0.017 15.4 0.1 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain tRNA-synt_2b PF00587.20 CAR25586.1 - 1.3e-34 119.2 0.1 3.4e-34 117.8 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 CAR25586.1 - 2.1e-22 79.2 9.3 2.1e-22 79.2 6.4 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain DUF1049 PF06305.6 CAR25586.1 - 0.033 13.6 0.0 0.083 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Atg31 PF09795.4 CAR25587.1 - 3.3e-46 156.9 4.9 4.1e-46 156.5 3.4 1.1 1 0 0 1 1 1 1 Autophagy-related protein 31 DEAD PF00270.24 CAR25588.1 - 1.1e-41 142.1 1.6 3.1e-41 140.6 0.7 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR25588.1 - 5.5e-27 93.4 0.2 3e-26 91.0 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CAR25588.1 - 0.00015 21.9 0.1 0.00043 20.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CAR25588.1 - 0.00058 19.5 0.2 0.0016 18.1 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain CMS1 PF14617.1 CAR25588.1 - 0.0043 16.1 0.1 0.0098 14.9 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit PhoH PF02562.11 CAR25588.1 - 0.0047 16.1 1.2 0.047 12.9 0.8 2.3 1 1 0 1 1 1 1 PhoH-like protein AAA_30 PF13604.1 CAR25588.1 - 0.017 14.6 0.8 0.061 12.9 0.5 1.8 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 CAR25588.1 - 0.02 14.7 0.2 0.035 13.9 0.1 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 CAR25588.1 - 0.026 14.1 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 Helicase tRNA-synt_1b PF00579.20 CAR25588.1 - 0.049 12.7 0.0 0.085 11.9 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) Helicase_C_2 PF13307.1 CAR25588.1 - 0.077 12.9 0.0 0.47 10.3 0.0 2.4 2 1 0 2 2 2 0 Helicase C-terminal domain PRK PF00485.13 CAR25589.1 - 6e-12 45.5 0.1 8.3e-12 45.0 0.1 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Ovate PF04844.8 CAR25589.1 - 0.086 12.6 0.4 0.18 11.6 0.3 1.5 1 0 0 1 1 1 0 Transcriptional repressor, ovate ACT_6 PF13740.1 CAR25590.1 - 0.012 15.3 0.2 0.086 12.5 0.0 2.5 3 0 0 3 3 3 0 ACT domain GCV_T PF01571.16 CAR25591.1 - 3.1e-65 219.4 0.0 3.9e-65 219.1 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 CAR25591.1 - 2.2e-13 50.0 0.0 3.6e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 CAR25591.1 - 0.021 14.6 0.0 0.69 9.7 0.0 2.3 1 1 1 2 2 2 0 Sarcosine oxidase, gamma subunit family MFS_1 PF07690.11 CAR25592.1 - 2.9e-29 101.9 23.0 2.9e-29 101.9 15.9 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1056 PF06341.6 CAR25592.1 - 0.28 11.2 3.9 13 5.9 0.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1056) Acyltransferase PF01553.16 CAR25593.1 - 9.8e-30 102.6 0.0 1.5e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF4083 PF13314.1 CAR25593.1 - 0.2 11.5 1.4 0.42 10.4 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) AMP-binding PF00501.23 CAR25594.1 - 9e-66 221.9 0.0 1.1e-65 221.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CAR25594.1 - 1.7e-05 25.6 0.0 3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fig1 PF12351.3 CAR25595.1 - 7.4e-58 195.4 3.2 7.4e-58 195.4 2.2 1.6 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 CAR25595.1 - 1e-05 25.1 8.1 1.5e-05 24.6 5.6 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF1469 PF07332.6 CAR25595.1 - 0.014 15.0 2.3 0.014 15.0 1.6 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1469) ATP-synt PF00231.14 CAR25596.1 - 4.3e-65 219.9 3.0 4.9e-65 219.7 2.1 1.0 1 0 0 1 1 1 1 ATP synthase IPK PF03770.11 CAR25597.1 - 2.5e-47 161.1 0.0 2.5e-47 161.1 0.0 3.0 3 0 0 3 3 3 2 Inositol polyphosphate kinase CENP-B_dimeris PF09026.5 CAR25597.1 - 3.6 7.9 22.5 0.38 11.0 3.8 3.3 3 0 0 3 3 3 0 Centromere protein B dimerisation domain DASH_Dad1 PF08649.5 CAR25598.1 - 5.1e-31 106.1 2.3 6.4e-31 105.8 1.6 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 UBN2 PF14223.1 CAR25598.1 - 0.0078 15.9 0.2 0.0094 15.7 0.1 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type GCR1_C PF12550.3 CAR25598.1 - 0.014 15.2 0.1 0.05 13.4 0.0 1.8 1 1 1 2 2 2 0 Transcriptional activator of glycolytic enzymes PNPOx_C PF10590.4 CAR25600.1 - 3.3e-20 71.3 3.8 6.2e-20 70.4 2.7 1.5 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 CAR25600.1 - 3.4e-11 42.9 0.0 5.5e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase YceG PF02618.11 CAR25600.1 - 0.036 13.0 0.0 0.052 12.5 0.0 1.2 1 0 0 1 1 1 0 YceG-like family Pyridox_oxase_2 PF12766.2 CAR25600.1 - 0.069 13.4 0.1 0.15 12.4 0.0 1.7 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Sld5 PF05916.6 CAR25602.1 - 3.6e-11 43.3 0.2 5.4e-11 42.7 0.2 1.3 1 0 0 1 1 1 1 GINS complex protein PIF1 PF05970.9 CAR25602.1 - 0.0022 17.0 0.0 0.0045 15.9 0.0 1.4 1 1 0 1 1 1 1 PIF1-like helicase DUF4062 PF13271.1 CAR25602.1 - 0.11 12.5 0.1 0.36 10.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4062) PAH PF02671.16 CAR25602.1 - 0.19 11.3 1.0 1.3 8.7 0.1 2.4 2 0 0 2 2 2 0 Paired amphipathic helix repeat Methyltransf_31 PF13847.1 CAR25603.1 - 3.2e-12 46.2 0.0 6.8e-12 45.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CAR25603.1 - 2.2e-11 43.4 0.0 3.7e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 CAR25603.1 - 8.8e-11 41.8 0.0 2.4e-10 40.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR25603.1 - 3.5e-10 40.4 0.0 1.4e-09 38.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CAR25603.1 - 9.6e-08 32.4 0.0 3.8e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAR25603.1 - 2.1e-07 30.8 0.0 5e-07 29.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.6 CAR25603.1 - 1.2e-06 27.4 0.1 1.6e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PRMT5 PF05185.11 CAR25603.1 - 4.8e-06 25.7 0.0 6e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase CMAS PF02353.15 CAR25603.1 - 1.2e-05 24.5 0.0 1.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 CAR25603.1 - 1.6e-05 24.3 0.0 4e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.1 CAR25603.1 - 2.4e-05 24.6 0.0 6.5e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 CAR25603.1 - 0.00021 21.3 0.0 0.00043 20.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_12 PF08242.7 CAR25603.1 - 0.00092 19.6 0.0 0.002 18.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 CAR25603.1 - 0.002 17.6 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Met_10 PF02475.11 CAR25603.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_2 PF00891.13 CAR25603.1 - 0.027 13.6 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_32 PF13679.1 CAR25603.1 - 0.03 14.0 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 CAR25603.1 - 0.037 13.5 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.8 CAR25603.1 - 0.052 12.8 0.8 0.22 10.7 0.1 2.0 1 1 0 2 2 2 0 Histone methylation protein DOT1 UPF0020 PF01170.13 CAR25603.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.12 CAR25603.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Ribosomal_L4 PF00573.17 CAR25604.1 - 1.2e-46 158.5 0.8 1.7e-46 158.0 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 CAR25604.1 - 2.3e-29 101.0 3.9 6.5e-29 99.6 0.9 2.5 2 1 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain SET PF00856.23 CAR25605.1 - 1.8e-07 31.6 0.1 0.14 12.4 0.0 3.8 3 1 0 3 3 3 2 SET domain CRA PF06589.6 CAR25605.1 - 0.17 11.1 0.7 0.34 10.1 0.5 1.4 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) NOA36 PF06524.7 CAR25605.1 - 0.24 10.6 5.6 0.44 9.7 3.9 1.3 1 0 0 1 1 1 0 NOA36 protein Eapp_C PF10238.4 CAR25605.1 - 0.32 10.9 5.1 0.76 9.6 3.6 1.6 1 0 0 1 1 1 0 E2F-associated phosphoprotein SDA1 PF05285.7 CAR25605.1 - 1.7 7.8 14.7 0.06 12.6 4.5 2.0 2 0 0 2 2 2 0 SDA1 IFT57 PF10498.4 CAR25605.1 - 5.6 5.6 11.2 0.25 10.0 2.2 2.1 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 RXT2_N PF08595.6 CAR25605.1 - 7.9 6.2 11.9 0.16 11.7 3.4 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal CTP_transf_1 PF01148.15 CAR25606.1 - 2.2e-77 260.2 23.0 2.8e-77 259.9 15.9 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF433 PF04255.9 CAR25606.1 - 0.084 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF433) Pkinase PF00069.20 CAR25607.1 - 2e-65 220.5 0.0 2.8e-65 220.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR25607.1 - 8.6e-36 123.3 0.0 1.1e-35 122.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CAR25607.1 - 0.002 17.8 0.1 0.5 10.0 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_C PF00433.19 CAR25607.1 - 0.0052 17.2 0.2 0.016 15.6 0.1 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 CAR25607.1 - 0.0082 15.1 0.0 0.057 12.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like ADH_zinc_N PF00107.21 CAR25608.1 - 2.8e-09 36.5 0.0 4.9e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CAR25608.1 - 0.064 13.0 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain EmrE PF13536.1 CAR25609.1 - 0.85 9.8 22.0 0.28 11.3 1.8 3.0 3 0 0 3 3 3 0 Multidrug resistance efflux transporter EamA PF00892.15 CAR25609.1 - 1.4 8.9 24.1 0.066 13.2 3.9 3.0 3 1 0 3 3 3 0 EamA-like transporter family YchF-GTPase_C PF06071.8 CAR25610.1 - 2e-36 123.5 0.1 5e-36 122.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 CAR25610.1 - 1.9e-12 47.1 0.0 3.7e-12 46.2 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CAR25610.1 - 0.0059 15.8 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 CAR25610.1 - 0.018 14.8 0.0 0.053 13.3 0.0 1.7 1 0 0 1 1 1 0 TGS domain SecA_PP_bind PF01043.15 CAR25610.1 - 0.049 13.9 0.4 0.53 10.6 0.0 2.2 2 0 0 2 2 2 0 SecA preprotein cross-linking domain Dna2 PF08696.6 CAR25610.1 - 0.076 12.3 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 DNA replication factor Dna2 MobB PF03205.9 CAR25610.1 - 0.12 12.0 1.3 3.3 7.3 0.0 3.0 3 1 1 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B SCO1-SenC PF02630.9 CAR25611.1 - 3.2e-68 228.7 0.0 4.2e-68 228.3 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 CAR25611.1 - 0.00028 20.5 0.0 0.00063 19.4 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Chitin_synth_1 PF01644.12 CAR25612.1 - 3.9e-78 260.8 0.3 6.1e-78 260.2 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 CAR25612.1 - 7.1e-24 84.0 3.2 1.1e-18 66.9 0.0 3.0 2 1 0 3 3 3 2 Chitin synthase Chitin_synth_1N PF08407.6 CAR25612.1 - 2.1e-23 81.8 0.1 5.6e-23 80.4 0.1 1.8 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 CAR25612.1 - 3.4e-11 43.1 0.4 3.4e-11 43.1 0.3 2.4 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CAR25612.1 - 2.9e-08 33.8 0.0 2.6e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Peptidase_M20 PF01546.23 CAR25613.1 - 3.5e-26 91.8 0.0 4.5e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CAR25613.1 - 8.9e-10 38.3 0.0 4.4e-09 36.0 0.0 2.2 3 0 0 3 3 3 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 CAR25613.1 - 5.9e-05 22.8 0.0 9.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Chitin_synth_2 PF03142.10 CAR25614.1 - 4.8e-289 959.1 0.1 8.1e-289 958.4 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 CAR25614.1 - 4.1e-17 62.5 2.5 1.7e-16 60.5 1.7 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CAR25614.1 - 6.3e-14 52.3 0.0 5.6e-11 42.6 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 CAR25614.1 - 3.2e-06 26.8 0.1 1.7e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 CAR25614.1 - 0.00017 20.9 0.1 0.00052 19.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 CAR25614.1 - 0.0013 18.4 0.0 0.021 14.5 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF1418 PF07214.7 CAR25614.1 - 1.4 8.5 6.4 3.9 7.1 4.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) Macro PF01661.16 CAR25615.1 - 8.7e-27 93.3 0.0 1.9e-26 92.2 0.0 1.5 1 1 0 1 1 1 1 Macro domain Abhydrolase_1 PF00561.15 CAR25615.1 - 0.018 14.6 0.2 0.023 14.2 0.2 1.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold Transp_cyt_pur PF02133.10 CAR25616.1 - 1.8e-161 537.6 43.3 2.1e-161 537.3 30.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ABC2_membrane PF01061.19 CAR25617.1 - 9.6e-67 224.2 61.8 1.1e-40 139.0 10.0 3.3 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 CAR25617.1 - 6.2e-37 126.9 0.0 1.1e-19 71.0 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 CAR25617.1 - 2.5e-35 120.2 4.2 2.8e-30 104.0 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 CAR25617.1 - 1.1e-11 44.6 0.1 3.3e-11 43.0 0.1 1.9 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 CAR25617.1 - 2.9e-05 23.5 0.0 0.002 17.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain DUF258 PF03193.11 CAR25617.1 - 3.4e-05 23.0 0.0 0.00034 19.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 CAR25617.1 - 0.0001 22.3 0.1 0.0037 17.2 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 CAR25617.1 - 0.00027 20.4 0.3 0.022 14.2 0.2 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 CAR25617.1 - 0.00034 20.1 0.1 0.0008 18.8 0.1 1.6 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 CAR25617.1 - 0.00096 18.6 0.1 0.7 9.3 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family ABC2_membrane_3 PF12698.2 CAR25617.1 - 0.00097 18.2 28.1 0.00097 18.2 19.5 4.4 2 2 0 2 2 2 1 ABC-2 family transporter protein Miro PF08477.8 CAR25617.1 - 0.0016 18.9 0.0 2.3 8.7 0.0 3.2 3 0 0 3 3 3 1 Miro-like protein AAA_18 PF13238.1 CAR25617.1 - 0.0016 18.7 0.0 0.0096 16.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CAR25617.1 - 0.0027 17.8 0.5 0.022 14.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CAR25617.1 - 0.0034 17.5 0.1 0.41 10.8 0.0 3.1 3 0 0 3 3 2 1 RNA helicase AAA_21 PF13304.1 CAR25617.1 - 0.0034 17.3 0.0 1.1 9.1 0.0 3.4 3 0 0 3 3 3 1 AAA domain SMC_N PF02463.14 CAR25617.1 - 0.0049 16.1 0.0 0.87 8.7 0.0 3.3 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 CAR25617.1 - 0.0063 17.3 1.2 0.026 15.3 0.0 2.6 4 0 0 4 4 1 1 AAA domain RecT PF03837.9 CAR25617.1 - 0.0066 15.7 0.3 0.1 11.8 0.0 2.2 2 0 0 2 2 2 1 RecT family UPF0079 PF02367.12 CAR25617.1 - 0.028 14.0 0.9 0.088 12.4 0.3 2.0 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 CAR25617.1 - 0.032 14.0 0.1 0.22 11.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 CAR25617.1 - 0.037 13.6 0.9 0.18 11.4 0.1 2.4 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.18 CAR25617.1 - 0.04 13.8 0.5 0.26 11.2 0.1 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.1 CAR25617.1 - 0.05 13.1 1.6 0.45 10.0 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 CAR25617.1 - 0.11 12.4 0.2 0.35 10.8 0.1 1.9 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CAR25617.1 - 0.56 9.9 2.9 4.4 7.1 0.0 2.9 3 0 0 3 3 3 0 Part of AAA domain GalKase_gal_bdg PF10509.4 CAR25618.1 - 3.4e-21 74.2 0.0 6.7e-21 73.3 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 CAR25618.1 - 4.1e-13 49.2 0.4 8.2e-13 48.2 0.3 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CAR25618.1 - 1.9e-12 47.1 0.0 4e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Aldose_epim PF01263.15 CAR25619.1 - 1e-58 198.8 0.0 1.7e-58 198.1 0.0 1.4 1 0 0 1 1 1 1 Aldose 1-epimerase Epimerase PF01370.16 CAR25619.1 - 3.3e-53 180.5 0.0 4.8e-53 180.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 CAR25619.1 - 1.4e-21 76.1 0.0 2.6e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 CAR25619.1 - 2.9e-17 62.2 0.0 2.4e-16 59.2 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 CAR25619.1 - 3.7e-14 52.3 0.0 9.8e-12 44.3 0.0 2.2 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 CAR25619.1 - 5.6e-11 41.8 0.0 1e-09 37.6 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 CAR25619.1 - 2.1e-10 39.9 0.0 3.4e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 CAR25619.1 - 9.7e-10 38.6 0.0 2e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CAR25619.1 - 3.8e-09 36.4 0.0 1.5e-08 34.5 0.0 1.9 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 CAR25619.1 - 8.2e-06 25.9 0.0 1.4e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CAR25619.1 - 0.084 12.1 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family UDPG_MGDP_dh_N PF03721.9 CAR25619.1 - 0.099 12.0 0.4 0.36 10.1 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DapB_N PF01113.15 CAR25619.1 - 0.13 12.1 0.5 0.38 10.6 0.0 2.0 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus GalP_UDP_transf PF01087.17 CAR25620.1 - 2.2e-64 216.8 0.0 5.3e-64 215.6 0.0 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 CAR25620.1 - 6.6e-60 201.4 0.1 1.5e-59 200.3 0.0 1.5 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 CAR25620.1 - 0.015 15.8 0.0 0.45 11.0 0.0 2.4 2 0 0 2 2 2 0 HIT domain AAA PF00004.24 CAR25621.1 - 3.2e-40 137.3 0.0 5.5e-40 136.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CAR25621.1 - 7.7e-07 29.3 0.1 0.00025 21.1 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 CAR25621.1 - 2.6e-06 27.4 0.0 6.2e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 CAR25621.1 - 2.1e-05 23.5 0.0 3.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 CAR25621.1 - 3.4e-05 23.5 0.2 0.00018 21.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CAR25621.1 - 0.0001 22.3 0.0 0.0038 17.2 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 CAR25621.1 - 0.00085 18.4 0.0 0.0017 17.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 CAR25621.1 - 0.0012 18.8 0.2 0.0034 17.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CAR25621.1 - 0.0034 17.2 0.0 0.0083 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CAR25621.1 - 0.0047 16.3 2.2 0.076 12.4 0.1 2.6 2 1 1 3 3 3 1 AAA domain AAA_17 PF13207.1 CAR25621.1 - 0.0051 17.6 0.6 0.012 16.3 0.1 2.0 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 CAR25621.1 - 0.0057 16.0 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 CAR25621.1 - 0.006 16.3 0.3 0.014 15.1 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 CAR25621.1 - 0.0067 16.7 0.1 0.03 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CAR25621.1 - 0.011 15.6 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CAR25621.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_3 PF07726.6 CAR25621.1 - 0.012 15.2 0.0 0.028 14.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 CAR25621.1 - 0.017 13.9 0.0 0.063 12.1 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain TIP49 PF06068.8 CAR25621.1 - 0.02 13.6 0.0 0.04 12.6 0.0 1.5 1 0 0 1 1 1 0 TIP49 C-terminus KaiC PF06745.8 CAR25621.1 - 0.024 13.7 0.1 0.35 9.9 0.0 2.3 1 1 1 2 2 2 0 KaiC NTPase_1 PF03266.10 CAR25621.1 - 0.031 13.9 0.1 0.22 11.2 0.0 2.3 2 0 0 2 2 2 0 NTPase NACHT PF05729.7 CAR25621.1 - 0.034 13.7 0.1 0.26 10.9 0.1 2.2 1 1 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 CAR25621.1 - 0.036 14.2 0.0 0.084 13.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.11 CAR25621.1 - 0.039 13.1 0.3 0.2 10.8 0.1 2.0 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.16 CAR25621.1 - 0.048 12.8 0.1 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 CAR25621.1 - 0.048 13.2 0.2 0.13 11.8 0.1 1.7 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 CAR25621.1 - 0.13 11.2 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PP2C PF00481.16 CAR25622.1 - 9.7e-75 251.2 0.5 1.5e-74 250.5 0.3 1.3 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 CAR25622.1 - 0.001 18.8 0.5 0.014 15.0 0.4 2.1 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Nitrate_red_del PF02613.10 CAR25622.1 - 0.025 14.4 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Nitrate reductase delta subunit Med2 PF11214.3 CAR25623.1 - 1.4e-31 108.6 8.7 1.4e-31 108.6 6.0 2.3 1 1 1 2 2 1 1 Mediator complex subunit 2 Caldesmon PF02029.10 CAR25623.1 - 0.02 13.3 22.0 0.03 12.7 15.3 1.2 1 0 0 1 1 1 0 Caldesmon Bud13 PF09736.4 CAR25623.1 - 0.091 13.0 16.3 0.15 12.3 11.3 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Dynamin_N PF00350.18 CAR25623.1 - 0.1 12.4 2.4 0.15 11.9 1.6 1.3 1 0 0 1 1 1 0 Dynamin family Ycf1 PF05758.7 CAR25623.1 - 0.22 9.2 11.6 0.24 9.0 8.0 1.1 1 0 0 1 1 1 0 Ycf1 SprA-related PF12118.3 CAR25623.1 - 0.23 10.7 17.3 0.33 10.2 12.0 1.2 1 0 0 1 1 1 0 SprA-related family NARP1 PF12569.3 CAR25623.1 - 0.3 9.7 13.6 0.4 9.3 9.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CDC45 PF02724.9 CAR25623.1 - 0.54 8.2 13.6 0.61 8.0 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Borrelia_P83 PF05262.6 CAR25623.1 - 0.89 7.7 16.5 1.2 7.3 11.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Neur_chan_memb PF02932.11 CAR25623.1 - 1 9.2 4.1 1.3 8.8 2.8 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1510 PF07423.6 CAR25623.1 - 1.9 7.8 16.0 2.8 7.2 11.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Cytochrom_NNT PF03264.9 CAR25623.1 - 2.7 7.4 7.9 3.6 6.9 5.5 1.2 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region DDHD PF02862.12 CAR25623.1 - 3.1 7.5 11.6 4.5 6.9 8.0 1.2 1 0 0 1 1 1 0 DDHD domain PBP_sp32 PF07222.7 CAR25623.1 - 3.5 6.7 15.2 4.9 6.2 10.5 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Hid1 PF12722.2 CAR25623.1 - 4.7 4.7 10.0 5.4 4.5 7.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Paramyxo_ncap PF00973.14 CAR25623.1 - 6.7 5.2 8.1 8.7 4.9 5.6 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF3464 PF11947.3 CAR25623.1 - 7.7 5.9 8.2 11 5.4 5.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DUF1682 PF07946.9 CAR25623.1 - 9.2 5.0 18.7 13 4.5 13.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF4407 PF14362.1 CAR25623.1 - 9.7 5.0 9.9 13 4.5 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_S64 PF08192.6 CAR25624.1 - 6 5.0 10.3 6.7 4.9 7.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 ATP-synt_DE_N PF02823.11 CAR25625.1 - 3.2e-19 68.4 0.1 5.5e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF1318 PF07027.7 CAR25625.1 - 0.13 12.5 0.4 13 6.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1318) Rad21_Rec8_N PF04825.8 CAR25626.1 - 1e-25 89.8 1.0 2.2e-25 88.7 0.2 1.9 2 0 0 2 2 2 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 CAR25626.1 - 1.4e-11 43.4 0.0 3.9e-11 41.9 0.0 1.8 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein DRIM PF07539.7 CAR25627.1 - 7.7e-46 155.0 0.2 4.8e-45 152.4 0.0 2.6 2 0 0 2 2 2 1 Down-regulated in metastasis HEAT PF02985.17 CAR25627.1 - 0.13 12.4 7.4 37 4.7 0.1 6.4 7 0 0 7 7 7 0 HEAT repeat YtzH PF14165.1 CAR25627.1 - 0.13 12.4 5.2 0.58 10.4 0.4 4.1 3 0 0 3 3 3 0 YtzH-like protein HMG_box PF00505.14 CAR25628.1 - 1.4e-15 57.3 2.6 4.1e-15 55.7 1.8 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CAR25628.1 - 3.3e-15 56.2 2.9 1e-14 54.6 2.0 1.9 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 CAR25628.1 - 0.033 13.9 2.3 0.059 13.1 0.7 2.0 2 0 0 2 2 2 0 HMG (high mobility group) box 5 DUF155 PF02582.9 CAR25629.1 - 7.4e-61 205.0 1.8 1.3e-60 204.2 1.3 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.1 CAR25629.1 - 0.015 15.4 0.0 0.042 14.0 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Histone PF00125.19 CAR25630.1 - 5.6e-26 90.4 0.0 7.2e-26 90.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CAR25630.1 - 2.3e-06 27.5 0.0 3.4e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CAR25631.1 - 4.9e-21 74.6 0.3 6.8e-21 74.1 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CAR25631.1 - 3.4e-05 23.8 0.1 3.4e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CAR25631.1 - 0.0035 17.5 0.0 0.0062 16.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Mitofilin PF09731.4 CAR25631.1 - 0.023 13.3 2.9 0.027 13.1 2.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Herpes_glycop_H PF02489.11 CAR25631.1 - 0.029 12.3 0.5 0.029 12.3 0.3 1.0 1 0 0 1 1 1 0 Herpesvirus glycoprotein H DUF1018 PF06252.7 CAR25631.1 - 0.13 12.7 0.7 0.18 12.3 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) DUF77 PF01910.12 CAR25632.1 - 4.1e-29 100.0 0.0 4.6e-29 99.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 Hom_end PF05204.9 CAR25633.1 - 0.11 12.4 0.1 0.29 11.1 0.0 1.8 1 1 0 1 1 1 0 Homing endonuclease Trehalase PF01204.13 CAR25635.1 - 5e-182 606.1 0.0 6.2e-182 605.8 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 CAR25635.1 - 1.2e-15 56.4 0.3 2e-15 55.7 0.2 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Rho_RNA_bind PF07497.7 CAR25635.1 - 0.034 13.7 0.0 0.095 12.3 0.0 1.7 1 0 0 1 1 1 0 Rho termination factor, RNA-binding domain Ran_BP1 PF00638.13 CAR25636.1 - 4.1e-54 181.8 1.1 5.7e-54 181.3 0.7 1.2 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 CAR25636.1 - 0.00025 20.7 0.6 0.0031 17.2 0.4 2.1 1 1 0 1 1 1 1 WH1 domain CDC27 PF09507.5 CAR25636.1 - 0.052 12.7 11.0 0.067 12.4 7.7 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF1681 PF07933.9 CAR25636.1 - 0.89 9.1 4.5 0.18 11.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1681) Prenyltransf PF01255.14 CAR25637.1 - 4.5e-77 258.1 0.0 5.6e-77 257.8 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase polyprenyl_synt PF00348.12 CAR25638.1 - 1e-51 175.3 0.3 2.7e-47 160.7 0.1 3.1 2 1 0 2 2 2 2 Polyprenyl synthetase Mannosyl_trans2 PF04188.8 CAR25639.1 - 3.1e-94 316.4 38.5 3.5e-92 309.6 26.7 2.0 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V)) Mpv17_PMP22 PF04117.7 CAR25639.1 - 5.4 6.7 11.0 1.2 8.8 0.1 3.4 3 0 0 3 3 3 0 Mpv17 / PMP22 family RCR PF12273.3 CAR25640.1 - 3.6e-33 114.9 0.5 5.6e-33 114.2 0.3 1.5 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red ATG27 PF09451.5 CAR25640.1 - 0.02 14.1 0.1 0.032 13.4 0.1 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 Ctr PF04145.10 CAR25640.1 - 0.12 12.4 0.1 0.2 11.6 0.1 1.6 1 1 0 1 1 1 0 Ctr copper transporter family Tetraspannin PF00335.15 CAR25640.1 - 0.15 11.2 0.0 0.39 9.9 0.0 1.3 1 1 1 2 2 2 0 Tetraspanin family Aldedh PF00171.17 CAR25641.1 - 1.7e-156 521.1 0.3 1.9e-156 521.0 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 CAR25641.1 - 4.3e-06 26.0 0.0 8e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) PTE PF02126.13 CAR25641.1 - 0.018 14.0 1.1 0.079 11.9 0.0 2.3 3 0 0 3 3 3 0 Phosphotriesterase family Rad51 PF08423.6 CAR25642.1 - 1.4e-28 99.5 0.0 3.4e-28 98.2 0.0 1.5 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.1 CAR25642.1 - 1.2e-11 44.3 0.1 4.2e-11 42.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain RecA PF00154.16 CAR25642.1 - 0.00077 18.6 0.9 0.0022 17.0 0.6 1.7 1 1 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 CAR25642.1 - 0.0029 16.7 0.9 0.0096 15.0 0.6 2.0 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.1 CAR25642.1 - 0.0095 16.0 0.1 0.028 14.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Maf1 PF09174.5 CAR25643.1 - 8.5e-48 162.5 2.9 2.2e-47 161.2 1.9 1.8 1 1 0 1 1 1 1 Maf1 regulator Sel1 PF08238.7 CAR25644.1 - 8.6e-08 32.5 1.6 0.046 14.3 0.0 3.5 3 0 0 3 3 3 3 Sel1 repeat BSMAP PF12280.3 CAR25644.1 - 0.0091 15.8 0.5 0.0091 15.8 0.4 2.8 2 1 1 3 3 3 1 Brain specific membrane anchored protein Tcp11 PF05794.8 CAR25645.1 - 4e-123 411.3 2.8 6.4e-123 410.7 1.9 1.3 1 0 0 1 1 1 1 T-complex protein 11 Histone PF00125.19 CAR25646.1 - 2.3e-15 56.4 0.3 2.8e-15 56.2 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CAR25646.1 - 1.6e-05 24.8 0.1 2.8e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 CAR25646.1 - 3.7e-05 23.5 0.2 5.2e-05 23.1 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 CAR25646.1 - 4.8e-05 23.4 0.1 6.6e-05 23.0 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 CAR25646.1 - 0.0013 18.1 0.0 0.0013 18.0 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CAR25646.1 - 0.0058 16.3 0.1 0.0072 16.0 0.0 1.3 1 1 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 CAR25646.1 - 0.04 14.1 0.0 0.067 13.4 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.10 CAR25646.1 - 0.13 11.9 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 CAR25647.1 - 5.2e-30 103.3 0.7 8.5e-30 102.7 0.5 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CAR25647.1 - 9.4e-07 28.9 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CAR25647.1 - 0.002 18.1 1.0 0.0025 17.8 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CAR25647.1 - 0.058 13.1 0.1 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated PRAI PF00697.17 CAR25648.1 - 6.9e-58 195.4 0.0 8.2e-58 195.2 0.0 1.0 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Aldolase PF01081.14 CAR25648.1 - 0.1 11.7 0.0 0.3 10.2 0.0 1.8 2 0 0 2 2 2 0 KDPG and KHG aldolase Pyrophosphatase PF00719.14 CAR25649.1 - 1.1e-52 177.5 0.2 1.5e-52 177.1 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase zf-Apc11 PF12861.2 CAR25650.1 - 6.2e-45 150.9 6.0 8.6e-45 150.5 4.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CAR25650.1 - 6e-30 103.1 7.6 1e-29 102.4 5.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CAR25650.1 - 9.6e-08 31.7 15.2 5.4e-07 29.3 10.6 2.1 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CAR25650.1 - 0.00042 19.9 12.4 0.0043 16.7 8.9 2.1 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CAR25650.1 - 0.0023 17.5 12.5 0.093 12.4 8.8 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CAR25650.1 - 0.0058 16.4 1.0 0.0058 16.4 0.7 2.3 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 CAR25650.1 - 0.0099 15.5 14.1 0.049 13.2 9.8 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAR25650.1 - 0.01 15.8 12.9 0.058 13.4 8.9 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CAR25650.1 - 0.014 15.0 13.1 0.4 10.3 6.3 3.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-HIT PF04438.11 CAR25650.1 - 0.017 14.7 3.7 0.017 14.7 2.6 2.0 2 0 0 2 2 2 0 HIT zinc finger FANCL_C PF11793.3 CAR25650.1 - 0.045 13.7 12.3 0.24 11.3 8.5 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H PF13771.1 CAR25650.1 - 0.051 13.7 6.9 0.12 12.5 4.9 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain FYDLN_acid PF09538.5 CAR25650.1 - 0.096 13.2 0.1 0.096 13.2 0.0 2.3 3 0 0 3 3 2 0 Protein of unknown function (FYDLN_acid) DZR PF12773.2 CAR25650.1 - 0.16 11.8 9.8 0.92 9.3 3.7 2.3 1 1 1 2 2 2 0 Double zinc ribbon zf-RING-like PF08746.6 CAR25650.1 - 0.23 11.4 11.7 1.5 8.9 8.1 2.2 1 1 0 1 1 1 0 RING-like domain CpXC PF14353.1 CAR25650.1 - 0.27 11.1 4.0 0.48 10.3 2.8 1.5 1 1 0 1 1 1 0 CpXC protein zf-HC5HC2H_2 PF13832.1 CAR25650.1 - 0.4 10.7 7.2 1 9.3 5.1 1.7 1 1 0 1 1 1 0 PHD-zinc-finger like domain RINGv PF12906.2 CAR25650.1 - 8.7 6.4 10.3 37 4.4 7.2 2.1 1 1 0 1 1 1 0 RING-variant domain Glutaredoxin PF00462.19 CAR25651.1 - 3.1e-15 55.9 0.0 4.8e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 CAR25651.1 - 0.0033 17.5 0.1 0.021 15.0 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like domain DIM PF08194.7 CAR25651.1 - 4.8 7.2 5.9 27 4.7 0.6 2.4 2 0 0 2 2 2 0 DIM protein Mannosyl_trans3 PF11051.3 CAR25652.1 - 2.8e-87 292.5 0.0 3.9e-87 292.0 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative CYSTM PF12734.2 CAR25653.1 - 3.5e-13 49.3 8.3 3.5e-13 49.3 5.8 4.5 2 1 0 2 2 2 1 Cysteine-rich TM module stress tolerance zf-C3HC4_2 PF13923.1 CAR25654.1 - 0.0032 17.4 0.1 0.0083 16.1 0.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAR25654.1 - 0.0053 16.4 0.2 0.015 14.9 0.1 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CAR25654.1 - 0.026 14.1 0.0 0.07 12.8 0.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CAR25654.1 - 0.031 13.9 0.4 0.084 12.5 0.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) IBR PF01485.16 CAR25654.1 - 2.3 8.1 4.7 5.7 6.8 0.0 2.7 1 1 1 2 2 2 0 IBR domain Fibrillarin PF01269.12 CAR25655.1 - 3.4e-109 363.1 0.0 4.1e-109 362.8 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 CAR25655.1 - 1.7e-05 24.4 0.1 2.8e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 CAR25655.1 - 0.073 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Steroid_dh PF02544.11 CAR25656.1 - 5.5e-31 107.3 11.3 8.8e-31 106.6 7.9 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PB1 PF00564.19 CAR25656.1 - 0.076 12.6 0.2 1.1 8.9 0.1 2.3 2 0 0 2 2 2 0 PB1 domain Pkinase PF00069.20 CAR25657.1 - 7.2e-42 143.3 0.0 8.9e-23 80.7 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CAR25657.1 - 4.7e-15 55.3 0.0 3.1e-09 36.2 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 CAR25657.1 - 0.00017 20.6 0.0 0.56 9.1 0.0 3.0 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 CAR25657.1 - 0.0038 16.9 0.0 0.0098 15.6 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family EMP24_GP25L PF01105.19 CAR25658.1 - 2.3e-31 108.9 0.0 2.8e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2361 PF10153.4 CAR25658.1 - 0.04 14.1 0.7 0.063 13.4 0.5 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) Amidohydro_1 PF01979.15 CAR25659.1 - 7.9e-30 104.6 0.0 5.4e-29 101.8 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 CAR25659.1 - 6.5e-26 91.9 0.0 2.5e-14 53.9 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 CAR25659.1 - 2.3e-10 40.2 0.1 5.6e-07 29.1 0.0 2.5 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_5 PF13594.1 CAR25659.1 - 1.6e-09 37.4 0.0 4.6e-09 35.9 0.0 1.8 2 0 0 2 2 2 1 Amidohydrolase HEAT_EZ PF13513.1 CAR25660.1 - 9.4e-19 67.3 0.1 4.7e-10 39.6 0.0 7.2 7 0 0 7 7 7 2 HEAT-like repeat HEAT PF02985.17 CAR25660.1 - 1.2e-18 65.3 7.7 0.0091 16.0 0.0 8.2 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.1 CAR25660.1 - 3.4e-13 49.6 0.0 6.8e-05 23.0 0.0 5.5 5 2 0 5 5 5 3 HEAT repeats Adaptin_N PF01602.15 CAR25660.1 - 2.2e-05 23.0 0.8 0.022 13.1 0.0 3.2 3 1 0 3 3 3 2 Adaptin N terminal region CLASP_N PF12348.3 CAR25660.1 - 0.0002 20.7 0.1 0.22 10.8 0.0 4.0 5 0 0 5 5 5 1 CLASP N terminal UNC45-central PF11701.3 CAR25660.1 - 0.00044 19.9 1.6 0.013 15.1 0.2 2.8 2 1 0 2 2 2 1 Myosin-binding striated muscle assembly central Vac14_Fab1_bd PF12755.2 CAR25660.1 - 0.0006 20.1 0.0 3 8.3 0.0 4.2 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 CAR25660.1 - 0.0037 17.1 0.7 0.018 14.9 0.1 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain CDC45 PF02724.9 CAR25660.1 - 1.1 7.2 4.0 1.7 6.6 2.8 1.2 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.7 CAR25660.1 - 9.6 4.4 11.8 14 3.9 8.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SH3_1 PF00018.23 CAR25661.1 - 9e-10 37.7 0.0 2.3e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CAR25661.1 - 0.00031 20.2 0.0 0.00063 19.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAICAR_synt PF01259.13 CAR25662.1 - 6.8e-98 326.7 0.0 8.2e-98 326.4 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase UPF0086 PF01868.11 CAR25662.1 - 0.088 12.4 0.2 0.45 10.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function UPF0086 HELP PF03451.9 CAR25662.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 HELP motif Pkinase PF00069.20 CAR25663.1 - 2.2e-57 194.1 0.1 3.1e-57 193.6 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR25663.1 - 3.6e-33 114.7 0.0 9.2e-33 113.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CAR25663.1 - 0.072 12.8 0.0 0.29 10.8 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family HHA PF05321.6 CAR25663.1 - 0.083 13.0 0.3 0.38 10.9 0.0 2.3 2 0 0 2 2 2 0 Haemolysin expression modulating protein ACCA PF03255.9 CAR25663.1 - 0.14 11.6 0.9 0.32 10.5 0.6 1.6 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Pkinase PF00069.20 CAR25664.1 - 8e-74 248.0 0.3 1.4e-73 247.2 0.2 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR25664.1 - 4.7e-56 189.7 0.1 1.1e-55 188.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR25664.1 - 8.9e-05 21.5 0.2 0.00042 19.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Carn_acyltransf PF00755.15 CAR25665.1 - 6.7e-190 632.0 0.0 7.7e-190 631.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Oxysterol_BP PF01237.13 CAR25666.1 - 6.2e-129 429.5 0.0 1.2e-128 428.6 0.0 1.5 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_5 PF13857.1 CAR25666.1 - 9.5e-12 44.7 0.1 2.5e-05 24.3 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CAR25666.1 - 2e-11 44.0 0.0 7.6e-05 22.9 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CAR25666.1 - 2.4e-10 40.6 0.0 0.0011 19.4 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CAR25666.1 - 3.1e-09 36.1 0.0 0.0015 18.2 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat PH PF00169.24 CAR25666.1 - 1.6e-08 34.7 0.0 5.3e-08 33.0 0.0 2.0 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 CAR25666.1 - 1.5e-07 31.3 0.2 3.7e-07 30.1 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Ank_3 PF13606.1 CAR25666.1 - 3.6e-06 26.6 0.0 0.065 13.5 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat PH_11 PF15413.1 CAR25666.1 - 6.3e-06 26.4 1.3 1.7e-05 24.9 0.2 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain Phos_pyr_kin PF08543.7 CAR25667.1 - 2.6e-77 259.3 0.1 3.3e-77 259.0 0.1 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 CAR25667.1 - 3e-62 210.1 0.2 4.1e-62 209.6 0.1 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family HK PF02110.10 CAR25667.1 - 3.8e-06 26.2 0.1 8.8e-06 25.0 0.1 1.6 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family PfkB PF00294.19 CAR25667.1 - 0.00035 19.8 0.0 0.00058 19.0 0.0 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase zf-C2H2_4 PF13894.1 CAR25668.1 - 1.8e-05 24.7 4.4 0.066 13.5 0.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CAR25668.1 - 0.00025 21.2 9.9 0.034 14.4 0.2 3.1 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CAR25668.1 - 0.076 13.3 3.2 1.1 9.6 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger double domain DUF2457 PF10446.4 CAR25668.1 - 0.52 8.9 18.0 1.1 7.9 12.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) His_Phos_1 PF00300.17 CAR25669.1 - 7.9e-40 136.5 0.0 2.3e-39 135.0 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Peptidase_M49 PF03571.10 CAR25670.1 - 4.1e-228 757.9 0.0 5.8e-228 757.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M49 Arginosuc_synth PF00764.14 CAR25671.1 - 1.2e-160 534.8 0.0 1.3e-160 534.6 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 CAR25671.1 - 0.00011 21.7 0.0 0.00016 21.2 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 CAR25671.1 - 0.00059 19.1 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 CAR25671.1 - 0.0035 15.9 0.0 0.0052 15.3 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase NAD_Gly3P_dh_N PF01210.18 CAR25672.1 - 5.7e-51 172.3 0.0 9.8e-51 171.5 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 CAR25672.1 - 4.2e-47 159.6 0.1 9.7e-47 158.4 0.1 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 CAR25672.1 - 0.021 15.2 0.0 5.8 7.4 0.0 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 CAR25672.1 - 0.04 14.2 0.1 0.41 10.9 0.1 2.3 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 CAR25672.1 - 0.081 12.5 0.3 1.6 8.3 0.1 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RNA_Me_trans PF04252.8 CAR25673.1 - 6.2e-76 254.1 0.0 6.9e-76 254.0 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Cpn10 PF00166.16 CAR25674.1 - 1.6e-25 88.8 0.0 1.8e-25 88.6 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit PRP3 PF08572.5 CAR25675.1 - 2.8e-57 193.6 20.2 4.7e-57 192.9 14.0 1.3 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 CAR25675.1 - 4.2e-31 107.2 0.6 4.2e-31 107.2 0.4 2.6 3 1 0 3 3 3 1 Protein of unknown function (DUF1115) YliH PF10799.3 CAR25675.1 - 0.081 12.6 0.2 2.1 8.0 0.1 2.6 1 1 2 3 3 3 0 Biofilm formation protein (YliH/bssR) Ribosomal_L35p PF01632.14 CAR25676.1 - 0.059 13.2 0.1 0.18 11.7 0.0 1.9 1 0 0 1 1 1 0 Ribosomal protein L35 Arf PF00025.16 CAR25677.1 - 1.8e-31 108.7 0.0 2.3e-30 105.0 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family Ras PF00071.17 CAR25677.1 - 2.7e-12 46.3 0.0 3.5e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR25677.1 - 3.6e-10 40.3 0.0 1.1e-09 38.8 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein G-alpha PF00503.15 CAR25677.1 - 7.6e-10 38.0 0.5 4.4e-08 32.2 0.0 2.3 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.18 CAR25677.1 - 5.3e-09 36.0 0.0 7.7e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CAR25677.1 - 1.8e-06 27.3 0.0 2.3e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CAR25677.1 - 2.8e-06 26.6 0.1 3.9e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 CAR25677.1 - 6.6e-06 25.6 0.0 0.00056 19.3 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CAR25677.1 - 0.00067 18.9 0.6 0.0016 17.7 0.4 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.12 CAR25677.1 - 0.0022 17.5 0.4 0.84 9.1 0.1 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein Dynamin_N PF00350.18 CAR25677.1 - 0.0036 17.1 0.3 0.014 15.2 0.1 1.9 1 1 1 2 2 2 1 Dynamin family Campylo_MOMP PF05538.6 CAR25677.1 - 0.038 12.3 0.0 0.05 11.9 0.0 1.1 1 0 0 1 1 1 0 Campylobacter major outer membrane protein AAA_17 PF13207.1 CAR25677.1 - 0.09 13.6 0.0 0.19 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 CAR25677.1 - 0.11 12.2 0.1 0.25 11.0 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF2470 PF10615.4 CAR25678.1 - 2.5e-08 34.0 0.0 3.9e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Pkinase PF00069.20 CAR25679.1 - 5.3e-76 255.1 0.0 8.7e-76 254.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR25679.1 - 2.8e-37 128.1 0.0 4.2e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 CAR25679.1 - 5.7e-20 71.2 1.4 5.7e-20 71.2 1.0 2.1 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 CAR25679.1 - 6.8e-10 38.3 0.0 1.9e-09 36.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 CAR25679.1 - 4.1e-05 22.9 0.8 8.4e-05 22.0 0.6 1.4 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 CAR25679.1 - 0.00012 20.7 0.3 0.00012 20.7 0.2 1.6 2 0 0 2 2 2 1 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.9 CAR25679.1 - 0.0035 16.4 1.5 0.004 16.2 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CAR25679.1 - 0.0052 16.5 0.1 0.62 9.7 0.2 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family SIR2 PF02146.12 CAR25680.1 - 5e-36 124.0 0.0 1.3e-21 77.1 0.0 2.4 2 0 0 2 2 2 2 Sir2 family Rpr2 PF04032.11 CAR25681.1 - 1.9e-14 53.2 1.6 2.2e-14 53.0 0.1 1.8 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-ribbon_3 PF13248.1 CAR25681.1 - 0.001 18.1 1.8 0.0049 16.0 0.2 2.2 2 0 0 2 2 2 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 CAR25681.1 - 0.0067 15.8 2.9 0.019 14.4 0.1 2.3 2 0 0 2 2 2 1 zinc-ribbon domain DZR PF12773.2 CAR25681.1 - 0.0073 16.0 1.0 0.016 14.9 0.6 1.6 1 1 0 1 1 1 1 Double zinc ribbon TetR_C PF02909.12 CAR25681.1 - 0.021 14.4 0.2 0.041 13.5 0.2 1.4 1 0 0 1 1 1 0 Tetracyclin repressor, C-terminal all-alpha domain PI3_PI4_kinase PF00454.22 CAR25681.1 - 0.18 11.2 1.8 0.28 10.6 1.3 1.3 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase GAGA_bind PF06217.7 CAR25681.1 - 0.25 11.2 7.7 0.3 10.9 5.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2296 PF10058.4 CAR25681.1 - 0.29 10.8 0.2 0.29 10.8 0.1 2.1 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Pex24p PF06398.6 CAR25682.1 - 2.8e-73 246.7 7.0 3.6e-73 246.4 4.8 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin WD40 PF00400.27 CAR25683.1 - 1.5e-05 24.6 15.2 4.6e-05 23.1 0.2 5.3 7 0 0 7 7 7 2 WD domain, G-beta repeat Clathrin_propel PF01394.15 CAR25683.1 - 0.031 14.5 0.1 12 6.3 0.0 3.3 3 0 0 3 3 3 0 Clathrin propeller repeat PQQ_3 PF13570.1 CAR25683.1 - 6.9 7.0 7.5 32 4.9 0.0 4.8 7 0 0 7 7 7 0 PQQ-like domain SET PF00856.23 CAR25684.1 - 2.5e-08 34.4 0.0 1.1e-07 32.3 0.0 1.9 1 1 0 1 1 1 1 SET domain polyprenyl_synt PF00348.12 CAR25684.1 - 0.036 12.9 0.1 0.073 11.9 0.1 1.4 1 0 0 1 1 1 0 Polyprenyl synthetase TPR_11 PF13414.1 CAR25685.1 - 2.9e-56 186.9 25.4 2.3e-17 62.3 0.1 6.3 4 2 1 6 6 6 6 TPR repeat TPR_1 PF00515.23 CAR25685.1 - 3.5e-47 156.1 17.7 3.6e-07 29.5 0.0 9.4 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.12 CAR25685.1 - 1e-36 121.8 20.9 7.7e-05 22.3 0.1 9.3 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_8 PF13181.1 CAR25685.1 - 1.8e-23 80.4 16.4 0.0045 16.6 0.0 8.9 8 1 1 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.1 CAR25685.1 - 7e-23 80.3 16.3 5.7e-10 39.0 1.3 5.8 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.1 CAR25685.1 - 3.4e-20 72.1 12.4 0.00021 21.8 0.0 6.8 4 3 2 6 6 6 6 Tetratricopeptide repeat TPR_14 PF13428.1 CAR25685.1 - 7.1e-18 63.4 12.1 0.68 10.7 0.0 9.6 5 3 5 10 10 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 CAR25685.1 - 4.8e-14 52.4 16.3 0.0051 17.1 0.3 7.1 4 3 3 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.1 CAR25685.1 - 4.1e-13 48.0 8.4 0.15 11.8 0.1 7.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 CAR25685.1 - 4e-11 42.1 6.1 0.37 11.1 0.0 7.7 7 0 0 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 CAR25685.1 - 7.8e-09 35.5 13.3 0.05 13.7 0.3 4.5 3 2 1 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CAR25685.1 - 2e-08 33.9 0.1 0.0053 16.5 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 CAR25685.1 - 2.5e-07 30.7 19.4 0.24 11.9 0.0 8.4 8 0 0 8 8 8 1 Tetratricopeptide repeat DUF3808 PF10300.4 CAR25685.1 - 0.00045 18.9 7.0 0.0023 16.5 0.2 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF3808) TPR_10 PF13374.1 CAR25685.1 - 0.0043 16.9 3.7 16 5.5 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 CAR25685.1 - 0.018 14.2 12.4 0.57 9.4 0.0 6.2 8 0 0 8 8 8 0 SHNi-TPR PPR PF01535.15 CAR25685.1 - 0.024 14.5 2.7 71 3.7 0.0 5.6 7 0 0 7 7 6 0 PPR repeat DUF627 PF04781.7 CAR25685.1 - 0.028 14.0 0.6 39 3.8 0.0 4.1 3 2 0 3 3 3 0 Protein of unknown function (DUF627) ChAPs PF09295.5 CAR25685.1 - 0.045 12.5 1.2 1.3 7.7 0.0 2.3 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) DNA_binding_2 PF13724.1 CAR25685.1 - 0.056 13.6 0.4 0.21 11.7 0.3 2.1 1 1 0 1 1 1 0 DNA-binding domain MAS20 PF02064.10 CAR25685.1 - 0.085 12.7 3.2 27 4.7 0.0 3.8 3 0 0 3 3 3 0 MAS20 protein import receptor DUF498 PF04430.9 CAR25685.1 - 0.24 10.9 2.2 9.8 5.7 0.1 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF498/DUF598) TPR_20 PF14561.1 CAR25685.1 - 0.27 11.3 9.8 7.1 6.8 0.1 5.4 3 3 2 5 5 5 0 Tetratricopeptide repeat Trypan_PARP PF05887.6 CAR25685.1 - 1.1 9.1 14.0 0.43 10.3 7.5 1.9 2 0 0 2 2 1 0 Procyclic acidic repetitive protein (PARP) XPC-binding PF09280.6 CAR25685.1 - 9.5 5.7 8.0 1.4 8.3 1.6 2.6 2 2 0 2 2 2 0 XPC-binding domain adh_short PF00106.20 CAR25686.1 - 7.6e-33 113.7 0.0 9.8e-33 113.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CAR25686.1 - 6.6e-14 52.2 0.1 8.4e-14 51.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CAR25686.1 - 2.2e-11 43.7 0.0 2.7e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 CAR25686.1 - 0.00034 19.6 0.1 0.00051 19.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 CAR25686.1 - 0.00044 19.7 0.2 0.0044 16.4 0.0 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 CAR25686.1 - 0.0007 18.8 0.0 0.0015 17.7 0.0 1.5 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 CAR25686.1 - 0.0045 16.7 0.3 0.0086 15.8 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AMMECR1 PF01871.12 CAR25687.1 - 8.4e-34 116.1 0.0 1e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 AMMECR1 APP_N PF02177.11 CAR25687.1 - 0.079 12.8 0.1 0.21 11.5 0.1 1.7 2 0 0 2 2 2 0 Amyloid A4 N-terminal heparin-binding Thioredoxin PF00085.15 CAR25688.1 - 8.7e-24 83.1 0.6 4.9e-23 80.7 0.1 2.2 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 CAR25688.1 - 6.3e-08 32.8 0.7 2.8e-07 30.7 0.5 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CAR25688.1 - 6.9e-06 26.0 0.5 0.0013 18.8 0.1 3.1 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_6 PF13848.1 CAR25688.1 - 1.1e-05 25.3 3.5 0.00059 19.6 1.6 3.1 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CAR25688.1 - 0.00083 19.3 0.2 0.003 17.5 0.1 2.0 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 CAR25688.1 - 0.0034 16.9 0.0 0.0071 15.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.1 CAR25688.1 - 0.005 16.3 0.1 0.013 14.9 0.0 1.7 2 0 0 2 2 2 1 F plasmid transfer operon protein AhpC-TSA PF00578.16 CAR25688.1 - 0.016 14.8 0.1 0.032 13.8 0.1 1.4 1 0 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.5 CAR25688.1 - 0.052 13.1 0.2 0.089 12.3 0.1 1.3 1 0 0 1 1 1 0 Redoxin DSBA PF01323.15 CAR25688.1 - 0.065 12.7 0.2 0.13 11.8 0.1 1.6 1 1 0 1 1 1 0 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.1 CAR25688.1 - 0.096 12.5 0.2 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin domain Abhydrolase_1 PF00561.15 CAR25688.1 - 0.11 12.0 0.0 0.43 10.1 0.0 1.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold MRP_L53 PF10780.4 CAR25689.1 - 2.3e-21 75.4 0.5 3.2e-21 75.0 0.4 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 DUF947 PF06102.7 CAR25690.1 - 4.3e-43 147.0 25.5 4.3e-43 147.0 17.6 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF947) Rhodanese PF00581.15 CAR25691.1 - 1e-14 54.8 0.0 1.3e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese PF00581.15 CAR25692.1 - 2e-17 63.5 0.0 2.5e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain His_Phos_1 PF00300.17 CAR25693.1 - 2.4e-29 102.4 0.0 2.9e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Mre11_DNA_bind PF04152.9 CAR25694.1 - 4.1e-53 179.8 0.1 1.2e-52 178.3 0.1 1.8 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 CAR25694.1 - 1.8e-28 99.3 1.0 2.9e-28 98.6 0.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CAR25694.1 - 0.00017 21.4 0.0 0.0012 18.6 0.0 2.2 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Phosducin PF02114.11 CAR25695.1 - 1.6e-12 46.7 6.3 6.7e-12 44.6 4.3 1.8 1 1 0 1 1 1 1 Phosducin APG6 PF04111.7 CAR25695.1 - 0.0006 18.9 0.7 0.00085 18.4 0.5 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 UCH PF00443.24 CAR25696.1 - 3.5e-55 187.0 4.4 6.3e-55 186.1 3.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CAR25696.1 - 8.6e-26 91.0 3.6 1.6e-25 90.1 2.5 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CAR25696.1 - 2.3e-11 43.6 8.3 2.3e-11 43.6 5.7 3.1 3 1 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein DZR PF12773.2 CAR25696.1 - 1.8 8.4 16.7 1.5 8.7 1.4 4.3 3 1 1 4 4 4 0 Double zinc ribbon FSH1 PF03959.8 CAR25697.1 - 2.5e-61 206.8 0.0 2.9e-61 206.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 CAR25697.1 - 2.3e-08 33.9 0.0 3e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CAR25697.1 - 2.1e-05 24.4 0.0 0.06 13.2 0.0 2.1 1 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CAR25697.1 - 0.00012 21.6 0.5 0.00031 20.2 0.1 1.9 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.5 CAR25697.1 - 0.049 13.5 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein FSH1 PF03959.8 CAR25698.1 - 1.1e-64 217.8 0.0 1.3e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 CAR25698.1 - 4.3e-08 33.0 0.0 5.8e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CAR25698.1 - 2.1e-05 24.0 0.2 4.7e-05 22.9 0.1 1.6 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.13 CAR25698.1 - 0.015 14.7 0.1 0.079 12.3 0.0 2.1 1 1 2 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 CAR25698.1 - 0.022 14.6 0.0 2.4 7.9 0.0 2.2 1 1 1 2 2 2 0 Alpha/beta hydrolase family MFS_1 PF07690.11 CAR25699.1 - 1.1e-15 57.2 8.3 1.1e-15 57.2 5.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Streptin-Immun PF11083.3 CAR25700.1 - 0.046 13.7 0.1 0.25 11.3 0.0 2.3 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein GHMP_kinases_N PF00288.21 CAR25701.1 - 2e-12 46.9 0.2 4.9e-12 45.7 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CAR25701.1 - 1.7e-06 28.1 0.0 4.2e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 GHMP kinases C terminal AA_permease_N PF08403.5 CAR25701.1 - 0.035 13.4 0.0 0.093 12.0 0.0 1.7 1 0 0 1 1 1 0 Amino acid permease N-terminal Trypan_PARP PF05887.6 CAR25702.1 - 0.0015 18.3 43.9 0.0015 18.3 30.4 9.5 6 2 2 10 10 10 2 Procyclic acidic repetitive protein (PARP) TRAPPC10 PF12584.3 CAR25703.1 - 1.1e-15 57.3 0.0 2.1e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.3 CAR25703.1 - 0.0012 18.3 0.0 0.0033 16.9 0.0 1.6 2 0 0 2 2 2 1 Foie gras liver health family 1 TPR_2 PF07719.12 CAR25703.1 - 0.074 13.0 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat HEM4 PF02602.10 CAR25704.1 - 3.8e-40 137.5 0.0 4.3e-40 137.3 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD GMP_synt_C PF00958.17 CAR25705.1 - 3.9e-41 138.6 0.0 7.9e-41 137.7 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 CAR25705.1 - 1.4e-40 138.7 0.0 2.2e-40 138.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CAR25705.1 - 2.2e-08 33.8 0.0 7.9e-08 32.0 0.0 2.0 1 1 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.12 CAR25705.1 - 3.1e-08 32.8 0.1 0.00018 20.5 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Arginosuc_synth PF00764.14 CAR25705.1 - 0.057 12.4 0.1 0.089 11.8 0.1 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase tRNA_Me_trans PF03054.11 CAR25705.1 - 0.062 11.8 0.0 0.12 10.8 0.0 1.5 1 0 0 1 1 1 0 tRNA methyl transferase PAPS_reduct PF01507.14 CAR25705.1 - 0.1 12.4 0.1 0.23 11.2 0.0 1.6 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family Asn_synthase PF00733.16 CAR25705.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase Pkinase PF00069.20 CAR25706.1 - 7.2e-43 146.5 0.6 8.1e-23 80.8 0.8 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAR25706.1 - 7.5e-11 41.5 2.5 3e-08 33.0 0.6 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase GKAP PF03359.8 CAR25706.1 - 2.3 7.7 5.4 0.18 11.3 0.2 1.6 2 0 0 2 2 2 0 Guanylate-kinase-associated protein (GKAP) protein Glyco_hydro_72 PF03198.9 CAR25707.1 - 2.7e-120 401.1 4.4 4e-120 400.5 3.0 1.2 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 CAR25707.1 - 2e-10 40.0 0.1 4.9e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 CAR25707.1 - 9.9e-07 28.2 0.2 0.013 14.7 0.0 2.7 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) HGTP_anticodon PF03129.15 CAR25707.1 - 0.058 13.3 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Anticodon binding domain Peptidase_S66 PF02016.10 CAR25707.1 - 0.12 11.2 0.1 0.4 9.5 0.0 1.8 2 0 0 2 2 2 0 LD-carboxypeptidase DnaJ PF00226.26 CAR25708.1 - 6.9e-27 92.9 0.4 1.1e-26 92.2 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 CAR25708.1 - 1.2e-14 54.0 16.4 1.9e-14 53.4 11.4 1.3 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 CAR25708.1 - 7e-13 48.2 0.0 2.3e-11 43.4 0.0 2.6 3 0 0 3 3 3 1 DnaJ C terminal domain FdhE PF04216.7 CAR25708.1 - 0.033 13.8 2.9 0.09 12.4 2.1 1.6 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation HypA PF01155.14 CAR25708.1 - 0.16 11.6 8.1 1.2 8.7 0.6 2.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Septin PF00735.13 CAR25710.1 - 1.3e-112 375.3 0.0 2e-112 374.8 0.0 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 CAR25710.1 - 2.1e-05 24.4 0.0 4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 CAR25710.1 - 0.00051 20.0 1.2 0.0027 17.7 0.1 2.6 1 1 1 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 CAR25710.1 - 0.0008 18.6 0.5 0.0008 18.6 0.4 2.3 2 1 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CAR25710.1 - 0.0011 19.0 0.0 0.0031 17.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 CAR25710.1 - 0.0014 18.0 0.8 0.01 15.2 0.0 2.4 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain IIGP PF05049.8 CAR25710.1 - 0.0033 16.3 0.0 0.007 15.2 0.0 1.7 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Miro PF08477.8 CAR25710.1 - 0.0039 17.6 0.0 0.02 15.4 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein AAA_10 PF12846.2 CAR25710.1 - 0.0073 15.7 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain MobB PF03205.9 CAR25710.1 - 0.0081 15.8 0.2 0.016 14.9 0.1 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 CAR25710.1 - 0.0089 15.8 4.8 0.54 10.0 0.0 3.1 2 1 1 3 3 3 1 Dynamin family FtsK_SpoIIIE PF01580.13 CAR25710.1 - 0.012 15.0 0.1 0.026 13.9 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AIG1 PF04548.11 CAR25710.1 - 0.012 14.6 0.0 0.03 13.4 0.0 1.6 1 0 0 1 1 1 0 AIG1 family AAA_24 PF13479.1 CAR25710.1 - 0.014 15.0 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CAR25710.1 - 0.017 15.2 0.0 0.043 13.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 CAR25710.1 - 0.035 14.3 0.2 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.7 CAR25710.1 - 0.046 13.3 0.1 0.095 12.3 0.1 1.5 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.21 CAR25710.1 - 0.075 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.1 CAR25710.1 - 0.12 12.2 1.0 0.21 11.4 0.1 1.9 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 CAR25710.1 - 0.91 8.2 4.8 1.7 7.3 0.1 2.9 3 0 0 3 3 3 0 ArgK protein DUF3970 PF13113.1 CAR25710.1 - 1.1 8.9 4.8 22 4.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3970) Pyr_redox_2 PF07992.9 CAR25711.1 - 1.4e-25 90.3 0.0 2.4e-25 89.6 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CAR25711.1 - 6.7e-20 71.2 0.2 3.7e-16 59.2 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CAR25711.1 - 2.8e-07 30.7 0.1 0.00039 20.5 0.0 2.7 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CAR25711.1 - 5.4e-06 25.5 1.5 0.39 9.5 0.1 3.7 3 1 0 4 4 4 3 Glucose inhibited division protein A Thi4 PF01946.12 CAR25711.1 - 7.6e-05 21.9 0.1 0.0012 17.9 0.0 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 CAR25711.1 - 0.00026 19.9 1.5 0.065 12.0 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain NAD_binding_7 PF13241.1 CAR25711.1 - 0.00045 20.4 0.0 0.12 12.5 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.1 CAR25711.1 - 0.00071 19.5 0.1 0.019 14.9 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 CAR25711.1 - 0.0017 17.3 0.2 4.6 6.0 0.1 3.2 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.2 CAR25711.1 - 0.0033 16.5 0.1 0.28 10.2 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 CAR25711.1 - 0.01 15.8 0.1 1.8 8.6 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 CAR25711.1 - 0.053 12.4 0.3 4.6 6.0 0.0 2.9 2 1 0 3 3 3 0 FAD dependent oxidoreductase ApbA PF02558.11 CAR25711.1 - 0.18 11.2 1.5 0.65 9.4 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA PX PF00787.19 CAR25712.1 - 1.5e-13 50.5 0.1 1.9e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 PX domain Aldo_ket_red PF00248.16 CAR25713.1 - 2.1e-51 174.4 0.0 2.5e-51 174.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PQ-loop PF04193.9 CAR25714.1 - 5.3e-36 121.9 6.3 7.5e-18 63.8 0.5 2.6 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 CAR25714.1 - 0.037 13.9 4.5 0.89 9.4 0.0 3.1 2 1 1 3 3 3 0 Sugar efflux transporter for intercellular exchange Pkinase PF00069.20 CAR25716.1 - 2.2e-71 240.0 0.0 4e-71 239.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR25716.1 - 6.8e-52 176.1 0.0 1e-51 175.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR25716.1 - 1.6e-07 30.6 0.2 1.1e-05 24.5 0.0 2.1 2 0 0 2 2 2 2 Kinase-like ATP-synt_S1 PF05827.7 CAR25718.1 - 1.7e-38 132.5 0.0 2e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) PGP_phosphatase PF09419.5 CAR25719.1 - 2.2e-68 228.8 0.0 2.5e-68 228.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 CAR25719.1 - 0.00052 19.6 0.0 0.00078 19.0 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like FAT PF02259.18 CAR25720.1 - 6.1e-71 239.2 8.1 6.1e-71 239.2 5.6 1.9 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 CAR25720.1 - 2e-46 158.3 1.2 6.3e-46 156.7 0.3 2.4 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 CAR25720.1 - 1.2e-05 24.6 0.3 5.4e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 FATC domain TPR_11 PF13414.1 CAR25720.1 - 0.019 14.6 0.6 0.081 12.5 0.1 2.3 2 0 0 2 2 2 0 TPR repeat Asp PF00026.18 CAR25721.1 - 1.3e-28 100.1 3.5 1.3e-28 100.1 2.4 2.3 2 1 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CAR25721.1 - 0.00078 19.4 0.1 0.00078 19.4 0.1 2.5 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal Sec23_trunk PF04811.10 CAR25722.1 - 1.8e-55 187.9 0.0 3.9e-55 186.8 0.0 1.6 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CAR25722.1 - 2.3e-19 68.7 0.1 6.4e-19 67.2 0.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 CAR25722.1 - 2e-12 47.4 0.0 4e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 CAR25722.1 - 8.3e-12 44.4 0.4 1.6e-11 43.5 0.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 CAR25722.1 - 9.5e-08 31.6 0.0 2.1e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Pal1 PF08316.6 CAR25723.1 - 7.7e-50 169.0 3.2 7.7e-50 169.0 2.2 2.5 3 0 0 3 3 3 1 Pal1 cell morphology protein Zip PF02535.17 CAR25723.1 - 0.4 9.6 7.0 0.54 9.2 4.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Sod_Fe_C PF02777.13 CAR25724.1 - 2.8e-09 36.7 0.6 0.0013 18.5 0.1 2.5 1 1 1 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Svf1 PF08622.5 CAR25725.1 - 3.9e-133 443.4 9.1 4.6e-133 443.2 6.3 1.1 1 0 0 1 1 1 1 Svf1-like Pox_Ag35 PF03286.9 CAR25725.1 - 0.19 11.2 6.3 0.45 10.0 4.4 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FAM176 PF14851.1 CAR25725.1 - 0.47 10.1 4.2 1 9.0 2.9 1.5 1 0 0 1 1 1 0 FAM176 family Sugar_tr PF00083.19 CAR25726.1 - 1.4e-168 561.1 35.2 1.6e-168 560.9 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR25726.1 - 6.5e-27 94.1 31.1 1.8e-23 82.8 13.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 CAR25726.1 - 5.9 4.8 8.6 1.6 6.7 3.2 1.8 2 0 0 2 2 2 0 Transmembrane secretion effector tRNA-synt_1d PF00750.14 CAR25727.1 - 1e-96 323.8 3.8 1.3e-96 323.5 2.7 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 CAR25727.1 - 3.8e-28 97.8 0.2 7.7e-28 96.8 0.2 1.5 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 CAR25727.1 - 1.2e-12 48.1 0.1 5.8e-11 42.7 0.0 2.8 3 0 0 3 3 3 1 Arginyl tRNA synthetase N terminal domain Fcf1 PF04900.7 CAR25728.1 - 1.9e-38 130.5 1.3 3.4e-38 129.7 0.1 1.8 2 0 0 2 2 2 1 Fcf1 DUF4411 PF14367.1 CAR25728.1 - 0.11 12.2 0.2 3.3 7.4 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4411) ING PF12998.2 CAR25729.1 - 5.7e-23 81.1 6.3 9e-23 80.5 4.4 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 CAR25729.1 - 2.8e-10 39.7 9.1 2.8e-10 39.7 6.3 1.7 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.1 CAR25729.1 - 0.0032 17.5 1.8 0.0094 16.0 0.1 2.2 2 0 0 2 2 2 1 PHD-like zinc-binding domain DUF2360 PF10152.4 CAR25729.1 - 0.013 15.8 2.9 0.015 15.6 1.6 1.5 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Sec34 PF04136.10 CAR25729.1 - 0.025 14.2 3.5 0.038 13.6 2.4 1.2 1 0 0 1 1 1 0 Sec34-like family zf-C4_Topoisom PF01396.14 CAR25729.1 - 0.096 12.2 2.4 9.4 5.8 0.0 2.5 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger DUF605 PF04652.11 CAR25729.1 - 0.13 11.6 6.1 0.17 11.2 4.3 1.1 1 0 0 1 1 1 0 Vta1 like MatE PF01554.13 CAR25730.1 - 9.6e-58 194.3 38.6 7.6e-35 119.9 5.5 3.1 2 1 1 3 3 3 2 MatE Abhydrolase_1 PF00561.15 CAR25731.1 - 4e-16 59.2 0.2 4.3e-15 55.8 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CAR25731.1 - 1.5e-07 31.5 0.1 3.7e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 CAR25731.1 - 0.0015 18.0 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Tannase PF07519.6 CAR25731.1 - 0.0015 17.3 0.0 0.0022 16.7 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 CAR25731.1 - 0.022 14.5 0.0 0.11 12.1 0.0 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family Ribosomal_S15 PF00312.17 CAR25732.1 - 5.6e-24 83.7 0.2 1.1e-23 82.7 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S15 DUF3487 PF11990.3 CAR25732.1 - 0.082 12.3 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) Gar1 PF04410.9 CAR25733.1 - 6.4e-41 139.3 1.3 1.1e-40 138.6 0.1 1.7 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region MMR_HSR1 PF01926.18 CAR25734.1 - 6.8e-17 61.4 0.0 1.4e-15 57.2 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 CAR25734.1 - 4.4e-07 29.2 0.0 7.5e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 CAR25734.1 - 9.2e-07 28.2 0.0 2.3e-06 26.9 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 CAR25734.1 - 1.5e-05 24.5 0.0 5.4e-05 22.7 0.0 1.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CAR25734.1 - 4.7e-05 23.2 0.1 0.12 12.1 0.1 2.5 1 1 0 2 2 2 2 Dynamin family SRPRB PF09439.5 CAR25734.1 - 9e-05 21.7 0.0 0.00076 18.7 0.0 2.1 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit IIGP PF05049.8 CAR25734.1 - 0.00073 18.4 0.0 0.0012 17.6 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Septin PF00735.13 CAR25734.1 - 0.0019 17.2 0.0 0.0032 16.5 0.0 1.3 1 0 0 1 1 1 1 Septin AIG1 PF04548.11 CAR25734.1 - 0.0028 16.7 0.0 0.0054 15.8 0.0 1.4 1 0 0 1 1 1 1 AIG1 family ABC_tran PF00005.22 CAR25734.1 - 0.0039 17.4 0.1 0.012 15.9 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 CAR25734.1 - 0.0047 16.4 0.1 0.01 15.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Miro PF08477.8 CAR25734.1 - 0.044 14.2 0.0 0.078 13.4 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein MobB PF03205.9 CAR25734.1 - 0.05 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 CAR25734.1 - 0.054 13.6 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Ras PF00071.17 CAR25734.1 - 0.14 11.5 0.2 0.63 9.4 0.0 1.9 2 0 0 2 2 2 0 Ras family PduV-EutP PF10662.4 CAR25734.1 - 0.17 11.3 0.2 2.7 7.4 0.2 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Xpo1 PF08389.7 CAR25735.1 - 0.0055 16.6 9.2 0.057 13.3 6.3 2.9 1 1 0 1 1 1 1 Exportin 1-like protein Brix PF04427.13 CAR25736.1 - 1.9e-42 145.0 3.7 2.8e-42 144.5 2.5 1.2 1 0 0 1 1 1 1 Brix domain Pex19 PF04614.7 CAR25736.1 - 0.0057 16.3 3.0 0.0075 15.9 2.1 1.2 1 0 0 1 1 1 1 Pex19 protein family Tho2 PF11262.3 CAR25736.1 - 0.2 10.6 4.4 0.47 9.4 3.1 1.6 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 SBDS PF01172.13 CAR25738.1 - 1.2e-18 66.6 1.5 1.3e-18 66.5 1.0 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SNF2_N PF00176.18 CAR25739.1 - 7e-77 258.1 0.1 1.4e-76 257.1 0.1 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain HSA PF07529.8 CAR25739.1 - 2.8e-16 59.0 5.4 2.8e-16 59.0 3.7 2.7 1 1 1 2 2 2 2 HSA Helicase_C PF00271.26 CAR25739.1 - 1.3e-13 50.6 0.0 3.4e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAR25739.1 - 2.4e-06 27.1 0.0 5.5e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase RRM_1 PF00076.17 CAR25740.1 - 2.5e-41 139.1 0.0 7e-17 60.8 0.0 4.1 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR25740.1 - 1.3e-25 89.0 0.0 1.8e-10 40.6 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR25740.1 - 2.6e-15 56.0 0.0 2.2e-09 37.0 0.0 3.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CAR25740.1 - 0.0047 16.6 0.0 0.013 15.2 0.0 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Plasmodium_Vir PF05795.6 CAR25740.1 - 0.062 12.4 0.1 0.42 9.7 1.1 1.5 2 0 0 2 2 2 0 Plasmodium vivax Vir protein PAT1 PF09770.4 CAR25740.1 - 0.066 11.4 35.7 0.096 10.9 24.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Gti1_Pac2 PF09729.4 CAR25740.1 - 0.089 12.6 2.8 0.16 11.8 1.9 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family FimP PF09766.4 CAR25740.1 - 0.18 10.8 21.8 0.27 10.2 15.1 1.1 1 0 0 1 1 1 0 Fms-interacting protein Neur_chan_memb PF02932.11 CAR25740.1 - 0.22 11.3 2.8 0.34 10.7 2.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pal1 PF08316.6 CAR25740.1 - 0.35 11.3 4.9 1.5 9.2 3.4 2.0 2 0 0 2 2 2 0 Pal1 cell morphology protein Suf PF05843.9 CAR25740.1 - 0.43 10.2 14.6 0.82 9.3 10.1 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) EIF4E-T PF10477.4 CAR25740.1 - 0.59 8.8 14.5 0.88 8.2 10.1 1.2 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Auxin_canalis PF05703.6 CAR25740.1 - 0.75 9.5 6.6 1.3 8.7 4.6 1.3 1 0 0 1 1 1 0 Auxin canalisation OATP PF03137.15 CAR25740.1 - 0.85 7.6 6.1 1.2 7.0 4.2 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SprA-related PF12118.3 CAR25740.1 - 1 8.5 34.0 2.2 7.5 23.6 1.5 1 0 0 1 1 1 0 SprA-related family DUF4175 PF13779.1 CAR25740.1 - 1.5 6.3 43.3 2.1 5.9 30.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4557 PF15101.1 CAR25740.1 - 2.4 7.9 21.3 3.8 7.2 14.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) RRM_3 PF08777.6 CAR25740.1 - 3.7 7.4 13.5 1.2e+02 2.5 9.3 2.5 1 1 0 1 1 1 0 RNA binding motif Serinc PF03348.10 CAR25740.1 - 4.9 5.7 11.1 7.2 5.2 7.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF3154 PF11351.3 CAR25740.1 - 5.9 6.6 9.0 12 5.7 6.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3154) DUF1840 PF08895.6 CAR25740.1 - 6 6.9 13.6 11 6.0 9.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) DUF106 PF01956.11 CAR25740.1 - 6.1 6.3 9.2 10 5.6 6.4 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF106 AAA_23 PF13476.1 CAR25740.1 - 7.7 6.7 17.7 12 6.1 12.3 1.3 1 0 0 1 1 1 0 AAA domain AIF_C PF14721.1 CAR25740.1 - 9.4 6.4 9.7 48 4.1 7.3 1.7 2 0 0 2 2 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term RF-1 PF00472.15 CAR25741.1 - 1.2e-38 131.3 4.1 2.6e-38 130.3 2.9 1.5 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 CAR25741.1 - 3.3e-30 104.1 0.0 1e-29 102.5 0.0 1.9 1 0 0 1 1 1 1 PCRF domain DUF1693 PF07984.7 CAR25741.1 - 0.043 12.9 1.4 1.2 8.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1693) Pkinase PF00069.20 CAR25742.1 - 1.4e-70 237.3 0.0 1.6e-70 237.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR25742.1 - 7e-31 107.2 0.0 9.4e-31 106.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CAR25742.1 - 2e-05 24.4 0.0 3.6e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CAR25742.1 - 0.0035 16.3 0.0 0.0041 16.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DAO PF01266.19 CAR25743.1 - 2.3e-45 155.0 0.0 2.8e-45 154.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CAR25743.1 - 1.5e-06 28.4 0.0 0.0025 17.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CAR25743.1 - 3.2e-06 27.0 0.0 8.1e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CAR25743.1 - 0.00082 19.7 0.7 0.0091 16.3 0.1 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CAR25743.1 - 0.012 14.4 0.0 0.38 9.5 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain K_oxygenase PF13434.1 CAR25743.1 - 0.022 13.6 0.1 3.5 6.4 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.13 CAR25743.1 - 0.029 14.3 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.9 CAR25743.1 - 0.057 11.8 0.7 0.18 10.2 0.1 2.0 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox_2 PF07992.9 CAR25743.1 - 0.091 12.6 0.3 1.2 8.9 0.0 2.1 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TPR_2 PF07719.12 CAR25744.1 - 3.5e-11 42.1 2.1 0.1 12.6 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 CAR25744.1 - 4.6e-09 35.7 3.3 0.00065 19.3 0.0 3.9 3 1 0 3 3 3 3 TPR repeat TPR_12 PF13424.1 CAR25744.1 - 1.7e-06 27.8 0.8 0.025 14.5 0.0 4.4 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 CAR25744.1 - 3.8e-06 26.2 3.1 0.035 13.8 0.0 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 CAR25744.1 - 0.00039 19.9 1.2 0.23 11.1 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 CAR25744.1 - 0.0011 19.5 0.0 0.015 15.9 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 CAR25744.1 - 0.0012 18.5 0.3 10 6.2 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 CAR25744.1 - 0.022 15.1 0.1 91 3.8 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 CAR25744.1 - 0.14 12.3 0.5 3.9 7.9 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_transf_22 PF03901.12 CAR25745.1 - 5.2e-106 355.1 23.9 6.1e-106 354.9 16.6 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family HECT PF00632.20 CAR25746.1 - 9.7e-87 291.0 1.0 9.7e-87 291.0 0.7 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.23 CAR25747.1 - 3e-13 49.9 0.1 6.3e-13 48.8 0.1 1.6 1 0 0 1 1 1 1 SPRY domain Homeobox PF00046.24 CAR25748.1 - 8.9e-19 66.8 2.6 2.6e-18 65.3 1.8 1.8 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 CAR25748.1 - 0.0018 17.9 0.4 0.0044 16.6 0.2 1.7 1 0 0 1 1 1 1 Homeobox KN domain Aldedh PF00171.17 CAR25749.1 - 1.4e-165 551.1 0.0 1.6e-165 550.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CAR25749.1 - 2.8e-05 23.0 0.0 4.8e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Aldedh PF00171.17 CAR25750.1 - 7.3e-169 561.9 0.5 8.3e-169 561.7 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CAR25750.1 - 0.061 12.0 0.0 0.093 11.4 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Zn_clus PF00172.13 CAR25751.1 - 4.8e-07 29.5 9.4 9.6e-07 28.6 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_mis_repair PF01119.14 CAR25752.1 - 1.3e-29 102.0 0.0 7.2e-29 99.6 0.0 2.1 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 CAR25752.1 - 6.8e-13 48.4 0.0 1.3e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CAR25752.1 - 8.7e-09 35.0 0.0 1.6e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Nse4_C PF08743.5 CAR25753.1 - 1.7e-25 88.8 0.0 6e-25 87.0 0.0 2.0 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 CAR25753.1 - 1.6e-13 50.2 2.1 7e-13 48.2 1.5 2.1 1 1 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Flu_M1_C PF08289.6 CAR25753.1 - 0.14 12.1 1.3 0.5 10.4 0.2 2.3 2 0 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain CTNNBL PF08216.6 CAR25753.1 - 0.34 10.5 0.1 0.34 10.5 0.1 2.6 3 0 0 3 3 3 0 Catenin-beta-like, Arm-motif containing nuclear Peptidase_M22 PF00814.20 CAR25754.1 - 7.6e-69 232.1 0.0 9.2e-69 231.9 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Mito_carr PF00153.22 CAR25755.1 - 2.5e-65 216.2 1.2 2.2e-22 78.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Abi PF02517.11 CAR25755.1 - 0.043 13.9 0.0 0.13 12.3 0.0 1.8 1 1 0 1 1 1 0 CAAX protease self-immunity LNS2 PF08235.8 CAR25756.1 - 1.4e-69 232.6 0.0 2.9e-68 228.3 0.0 2.2 1 1 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 CAR25756.1 - 1.3e-43 147.1 0.0 3e-43 145.9 0.0 1.7 1 0 0 1 1 1 1 lipin, N-terminal conserved region AF1Q PF15017.1 CAR25756.1 - 0.00017 21.4 0.3 0.00017 21.4 0.2 3.2 2 0 0 2 2 2 1 Drug resistance and apoptosis regulator LisH PF08513.6 CAR25757.1 - 4.1e-07 29.5 0.3 6.4e-07 28.9 0.2 1.3 1 0 0 1 1 1 1 LisH Vezatin PF12632.2 CAR25758.1 - 5.9e-38 130.3 12.5 1.6e-37 128.9 8.7 1.7 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes IPP-2 PF04979.9 CAR25758.1 - 0.014 15.6 5.0 0.029 14.6 3.5 1.5 1 0 0 1 1 1 0 Protein phosphatase inhibitor 2 (IPP-2) DUF384 PF04064.8 CAR25758.1 - 0.046 13.2 0.1 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF384) UDPGP PF01704.13 CAR25759.1 - 4.1e-48 163.9 0.0 5.7e-48 163.4 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 CAR25759.1 - 0.073 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain E1-E2_ATPase PF00122.15 CAR25760.1 - 1.4e-17 63.4 0.0 3.9e-17 62.0 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CAR25760.1 - 5.3e-16 59.6 0.4 5.5e-12 46.5 0.3 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 CAR25760.1 - 2.2e-13 50.8 0.7 4.7e-12 46.4 0.5 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CAR25760.1 - 7.5e-13 48.2 0.0 3.2e-12 46.2 0.0 2.1 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CAR25760.1 - 0.0009 18.8 1.6 0.0009 18.8 1.1 3.6 5 1 0 5 5 5 1 haloacid dehalogenase-like hydrolase DnaJ PF00226.26 CAR25761.1 - 4.7e-26 90.3 0.6 8.9e-26 89.4 0.4 1.5 1 0 0 1 1 1 1 DnaJ domain DUF633 PF04816.7 CAR25761.1 - 0.014 14.7 0.1 0.019 14.2 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF633) DNA_pol_B PF00136.16 CAR25762.1 - 1.6e-133 445.8 1.6 2.2e-133 445.4 1.1 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CAR25762.1 - 1.2e-86 290.5 0.4 1.9e-86 289.9 0.3 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 CAR25762.1 - 1.2e-23 82.8 4.9 2.6e-23 81.8 3.4 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 CAR25762.1 - 0.00018 21.3 1.2 0.002 17.9 0.4 2.9 2 1 0 2 2 2 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 CAR25762.1 - 0.0036 16.8 0.0 0.007 15.9 0.0 1.5 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Pkinase PF00069.20 CAR25763.1 - 8.4e-73 244.7 0.0 1.1e-72 244.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR25763.1 - 2.2e-35 122.0 0.0 2.8e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 CAR25763.1 - 6.8e-16 58.1 1.6 1.5e-15 57.0 1.1 1.6 1 0 0 1 1 1 1 FHA domain Kdo PF06293.9 CAR25763.1 - 0.00031 19.8 0.1 0.00053 19.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CAR25763.1 - 0.059 12.3 1.8 9.9 5.0 0.1 3.5 3 1 1 4 4 4 0 Kinase-like ATG16 PF08614.6 CAR25765.1 - 2.8e-24 86.0 14.0 7.5e-23 81.3 7.0 2.0 2 0 0 2 2 2 2 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.3 CAR25765.1 - 0.0071 16.0 6.8 0.011 15.4 4.7 1.4 1 1 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF641 PF04859.7 CAR25765.1 - 0.0089 15.7 1.4 0.0089 15.7 1.0 1.8 1 1 1 2 2 2 1 Plant protein of unknown function (DUF641) EF-hand_2 PF09068.6 CAR25765.1 - 0.012 15.7 0.7 0.017 15.1 0.5 1.2 1 0 0 1 1 1 0 EF hand IncA PF04156.9 CAR25765.1 - 0.014 15.0 8.0 0.017 14.7 5.5 1.2 1 0 0 1 1 1 0 IncA protein GAS PF13851.1 CAR25765.1 - 0.016 14.4 8.1 0.023 13.8 5.6 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF469 PF04320.9 CAR25765.1 - 0.018 15.7 2.3 0.8 10.5 0.1 2.3 1 1 1 2 2 2 0 Protein with unknown function (DUF469) CENP-F_leu_zip PF10473.4 CAR25765.1 - 0.029 14.2 6.9 0.036 13.9 4.8 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.10 CAR25765.1 - 0.029 14.4 4.1 0.042 13.8 2.9 1.4 1 1 0 1 1 1 0 Fez1 Macoilin PF09726.4 CAR25765.1 - 0.064 11.5 3.8 0.067 11.4 2.6 1.1 1 0 0 1 1 1 0 Transmembrane protein TBPIP PF07106.8 CAR25765.1 - 0.1 12.1 9.6 0.11 12.0 3.7 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TMF_DNA_bd PF12329.3 CAR25765.1 - 0.21 11.4 12.9 0.94 9.3 8.9 2.0 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding KLRAQ PF10205.4 CAR25765.1 - 0.34 10.9 6.0 0.57 10.2 3.8 1.8 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein Ax_dynein_light PF10211.4 CAR25765.1 - 0.35 10.6 6.2 0.48 10.2 4.3 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain ADIP PF11559.3 CAR25765.1 - 0.41 10.5 9.9 0.51 10.2 1.8 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.7 CAR25765.1 - 0.44 10.2 8.7 0.34 10.6 4.9 1.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.4 CAR25765.1 - 0.61 8.9 6.7 0.74 8.6 4.6 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF972 PF06156.8 CAR25765.1 - 1.1 9.6 6.7 2.4 8.5 4.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Prefoldin_2 PF01920.15 CAR25765.1 - 1.2 8.9 8.9 5 6.9 0.2 2.8 1 1 2 3 3 3 0 Prefoldin subunit Val_tRNA-synt_C PF10458.4 CAR25765.1 - 2.2 8.4 10.1 6.8 6.8 0.6 2.9 1 1 2 3 3 3 0 Valyl tRNA synthetase tRNA binding arm HALZ PF02183.13 CAR25765.1 - 4.8 6.9 9.1 78 3.1 2.1 4.0 2 2 1 3 3 3 0 Homeobox associated leucine zipper DivIC PF04977.10 CAR25765.1 - 6.2 6.3 9.4 4.8 6.7 1.7 2.7 1 1 2 3 3 3 0 Septum formation initiator TPD52 PF04201.10 CAR25765.1 - 8.7 6.0 8.0 5.4 6.7 1.8 2.1 1 1 1 2 2 2 0 Tumour protein D52 family bZIP_1 PF00170.16 CAR25765.1 - 9.2 6.3 8.7 3.6 7.6 1.8 2.6 1 1 1 3 3 3 0 bZIP transcription factor ArsA_ATPase PF02374.10 CAR25766.1 - 7.9e-116 386.3 0.0 9.2e-116 386.1 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 CAR25766.1 - 7.8e-13 48.2 0.4 1.5e-12 47.3 0.3 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 CAR25766.1 - 3.9e-05 23.6 0.0 0.00032 20.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 CAR25766.1 - 0.00047 19.4 0.0 0.00097 18.4 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 CAR25766.1 - 0.0018 17.7 0.0 0.087 12.2 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 CAR25766.1 - 0.014 14.8 0.0 0.031 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CAR25766.1 - 0.019 14.6 0.0 0.045 13.4 0.0 1.7 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.11 CAR25766.1 - 0.026 13.7 0.0 0.052 12.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein T2SE PF00437.15 CAR25766.1 - 0.056 12.3 0.0 0.12 11.2 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 CAR25766.1 - 0.069 12.2 0.0 0.23 10.5 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin SlyX PF04102.7 CAR25767.1 - 0.0023 18.2 7.6 0.0023 18.2 5.2 4.1 5 1 0 5 5 5 1 SlyX Cob_adeno_trans PF01923.13 CAR25767.1 - 0.0087 15.8 0.4 0.0087 15.8 0.3 2.6 2 2 1 3 3 3 1 Cobalamin adenosyltransferase Streptin-Immun PF11083.3 CAR25767.1 - 0.028 14.3 4.8 0.028 14.3 3.3 2.0 2 1 0 2 2 2 0 Lantibiotic streptin immunity protein FlaC_arch PF05377.6 CAR25767.1 - 0.68 9.8 15.9 0.55 10.1 2.0 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) BLOC1_2 PF10046.4 CAR25767.1 - 1 9.5 14.8 0.13 12.3 5.3 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Macoilin PF09726.4 CAR25767.1 - 4.9 5.3 33.5 6.6 4.8 23.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Ribosomal_S8 PF00410.14 CAR25768.1 - 6.1e-20 71.3 0.0 7.2e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 zf-met PF12874.2 CAR25770.1 - 7.1e-06 26.0 1.9 1.5e-05 25.0 1.3 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CAR25770.1 - 0.032 14.3 2.6 0.076 13.1 1.8 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DNA_pol_B_palm PF14792.1 CAR25770.1 - 0.057 13.4 0.1 0.11 12.5 0.1 1.6 1 1 0 1 1 1 0 DNA polymerase beta palm zf-DBF PF07535.7 CAR25770.1 - 0.18 11.5 1.7 0.43 10.2 1.2 1.6 1 0 0 1 1 1 0 DBF zinc finger DUF1690 PF07956.6 CAR25770.1 - 0.26 11.2 3.0 0.96 9.4 0.5 2.0 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) PNK3P PF08645.6 CAR25771.1 - 1.8e-40 138.0 0.0 2.1e-40 137.7 0.0 1.0 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase PCI PF01399.22 CAR25772.1 - 1.3e-17 63.9 0.2 6.6e-17 61.7 0.0 2.3 2 0 0 2 2 1 1 PCI domain TPR_16 PF13432.1 CAR25772.1 - 2.9e-06 27.7 2.1 0.026 15.1 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.1 CAR25772.1 - 0.00092 18.3 2.9 0.00092 18.3 2.0 1.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 CAR25772.1 - 0.0017 18.2 5.7 0.16 11.8 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CAR25772.1 - 0.0063 16.8 2.3 18 5.7 0.0 3.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.1 CAR25772.1 - 0.012 15.6 3.5 1.8 8.7 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4600 PF15372.1 CAR25772.1 - 0.018 15.2 0.5 0.063 13.5 0.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) DDRGK PF09756.4 CAR25772.1 - 0.021 14.2 0.4 0.047 13.0 0.0 1.8 2 0 0 2 2 2 0 DDRGK domain TPR_11 PF13414.1 CAR25772.1 - 0.14 11.8 5.2 1.1 8.8 0.1 3.5 4 0 0 4 4 4 0 TPR repeat TPR_21 PF09976.4 CAR25772.1 - 0.39 10.6 5.0 5.2 6.9 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 CAR25772.1 - 0.44 10.7 17.5 0.057 13.5 1.1 4.2 5 0 0 5 5 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CAR25772.1 - 0.69 10.5 7.4 3.7 8.1 0.1 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat PMT PF02366.13 CAR25773.1 - 3.7e-78 262.2 18.8 3.7e-78 262.2 13.0 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CAR25773.1 - 1.8e-48 164.5 0.0 2.7e-48 164.0 0.0 1.2 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.1 CAR25773.1 - 5e-05 23.2 15.9 5e-05 23.2 11.0 2.7 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Nodulin-like PF06813.8 CAR25774.1 - 2.5e-13 49.8 5.1 6e-13 48.6 3.5 1.6 1 0 0 1 1 1 1 Nodulin-like SRP14 PF02290.10 CAR25775.1 - 3.5e-22 78.1 0.3 6.4e-22 77.2 0.2 1.4 1 0 0 1 1 1 1 Signal recognition particle 14kD protein UBX PF00789.15 CAR25776.1 - 4.2e-16 58.7 0.0 7.2e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain Prenyltrans PF00432.16 CAR25777.1 - 1.1e-42 143.2 3.0 1.5e-12 46.8 0.0 5.4 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CAR25777.1 - 8.3e-22 77.7 0.0 2.5e-14 53.6 0.0 3.0 1 1 2 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 CAR25777.1 - 0.001 19.0 0.2 1.2 9.1 0.0 2.8 3 1 1 4 4 4 2 Prenyltransferase-like Crl PF07417.7 CAR25777.1 - 0.011 15.4 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator Crl ACTH_domain PF00976.13 CAR25777.1 - 0.099 12.4 0.2 0.2 11.5 0.2 1.4 1 0 0 1 1 1 0 Corticotropin ACTH domain DUF2418 PF10332.4 CAR25779.1 - 1.8e-20 73.1 1.0 3.6e-20 72.1 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) Nup35_RRM PF05172.8 CAR25780.1 - 5.4e-33 112.7 0.0 1e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 CAR25780.1 - 0.00082 19.1 0.1 0.0025 17.5 0.0 1.8 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif ADH_zinc_N_2 PF13602.1 CAR25781.1 - 1.2e-13 52.0 0.0 2.3e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 CAR25781.1 - 4.1e-07 29.5 0.0 7.7e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CAR25781.1 - 1.4e-05 24.7 0.0 3.3e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain LUC7 PF03194.10 CAR25782.1 - 1.6e-74 250.6 6.1 1.8e-74 250.5 4.2 1.0 1 0 0 1 1 1 1 LUC7 N_terminus MtrG PF04210.8 CAR25782.1 - 0.85 9.3 2.8 13 5.5 0.2 2.9 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G adh_short PF00106.20 CAR25783.1 - 6.4e-11 42.4 0.0 1.3e-10 41.4 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Noelin-1 PF12308.3 CAR25783.1 - 0.0014 18.4 0.0 0.003 17.3 0.0 1.5 1 0 0 1 1 1 1 Neurogenesis glycoprotein Peptidase_S24 PF00717.18 CAR25784.1 - 5e-07 29.2 0.1 4.5e-06 26.2 0.0 2.3 1 1 1 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.4 CAR25784.1 - 0.0071 15.8 0.0 0.013 15.0 0.0 1.5 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Ribophorin_II PF05817.9 CAR25785.1 - 7.7e-06 24.4 2.2 9.6e-06 24.0 1.5 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II DUF4460 PF14687.1 CAR25787.1 - 0.15 11.8 1.6 0.23 11.2 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) T5orf172 PF10544.4 CAR25788.1 - 1.1e-07 32.1 0.6 4.1e-06 27.0 0.4 2.2 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.1 CAR25788.1 - 9.6e-07 29.1 0.4 1.9e-05 24.9 0.3 2.2 1 1 0 1 1 1 1 Meiotically up-regulated gene 113 DLH PF01738.13 CAR25789.1 - 1.3e-23 83.3 0.0 1.5e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 CAR25789.1 - 6.7e-06 25.9 0.0 9.1e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CAR25789.1 - 1.2e-05 24.6 0.3 8.3e-05 21.8 0.0 2.4 2 1 0 2 2 2 1 Prolyl oligopeptidase family DUF2305 PF10230.4 CAR25789.1 - 0.016 14.6 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Chlorophyllase2 PF12740.2 CAR25789.1 - 0.038 12.8 0.0 0.049 12.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.6 CAR25789.1 - 0.085 11.6 0.1 0.13 11.0 0.1 1.2 1 0 0 1 1 1 0 Chlorophyllase WD40 PF00400.27 CAR25790.1 - 1.3e-29 100.9 8.4 7.4e-08 31.9 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 CAR25790.1 - 3.9e-06 26.7 0.2 0.066 12.9 0.1 3.0 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 CAR25790.1 - 0.035 12.4 0.1 0.25 9.5 0.0 2.3 2 1 1 3 3 3 0 Cytochrome D1 heme domain 2-Hacid_dh_C PF02826.14 CAR25791.1 - 8.4e-39 132.5 0.0 3.2e-38 130.6 0.0 1.9 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CAR25791.1 - 1.2e-17 63.6 0.1 1.6e-17 63.2 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Pyr_redox_2 PF07992.9 CAR25792.1 - 2.6e-25 89.4 0.0 2e-16 60.4 0.0 3.6 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CAR25792.1 - 1.3e-12 47.9 0.0 1.3e-11 44.7 0.0 2.7 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CAR25792.1 - 1.9e-06 28.0 0.0 0.029 14.4 0.0 3.2 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HTH_psq PF05225.11 CAR25793.1 - 0.0057 16.1 0.0 0.018 14.5 0.0 1.9 1 0 0 1 1 1 1 helix-turn-helix, Psq domain Reo_sigmaC PF04582.7 CAR25793.1 - 0.049 12.8 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DEAD PF00270.24 CAR25794.1 - 1.6e-34 118.8 0.2 3.9e-34 117.5 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR25794.1 - 8.2e-22 76.8 0.0 6.6e-21 73.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAR25794.1 - 3.5e-05 23.7 0.0 9.7e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ribosomal_S9 PF00380.14 CAR25796.1 - 1.1e-38 132.1 0.2 1.3e-38 131.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L13e PF01294.13 CAR25797.1 - 6.8e-70 234.1 4.6 9e-70 233.7 3.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Ribosomal_60s PF00428.14 CAR25798.1 - 2.5e-23 82.2 10.1 3e-23 82.0 7.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Aminotran_3 PF00202.16 CAR25800.1 - 5e-58 196.5 0.0 6.1e-58 196.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 CAR25800.1 - 0.00042 19.5 0.0 0.00083 18.5 0.0 1.5 2 0 0 2 2 2 1 Beta-eliminating lyase Pyridoxal_deC PF00282.14 CAR25800.1 - 0.04 12.3 0.0 0.069 11.5 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.16 CAR25800.1 - 0.087 11.7 0.0 0.45 9.4 0.0 2.1 2 1 1 3 3 3 0 Aminotransferase class I and II TPP_enzyme_N PF02776.13 CAR25801.1 - 2.1e-31 108.7 0.0 3.2e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 CAR25801.1 - 3.3e-24 85.2 0.0 6.2e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 CAR25801.1 - 1.1e-14 54.2 0.1 2.1e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Pkinase PF00069.20 CAR25802.1 - 2.9e-60 203.6 0.0 3.5e-60 203.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR25802.1 - 2.6e-26 92.2 0.0 3.8e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CAR25802.1 - 0.0068 16.1 0.0 0.019 14.7 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CAR25802.1 - 0.02 14.4 0.1 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ldh_1_N PF00056.18 CAR25803.1 - 1.2e-44 151.5 0.2 2.1e-44 150.8 0.2 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CAR25803.1 - 7.9e-40 136.4 0.0 1.1e-39 135.9 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 CAR25803.1 - 1.5e-06 27.1 0.0 2.1e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 CAR25803.1 - 0.013 15.7 0.0 0.03 14.6 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 CAR25803.1 - 0.087 12.8 0.1 0.18 11.7 0.1 1.5 1 1 0 1 1 1 0 NADH(P)-binding Arf PF00025.16 CAR25804.1 - 1.4e-42 144.8 0.0 1.7e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 CAR25804.1 - 2.9e-12 45.9 1.9 3.4e-07 29.2 0.2 2.9 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 CAR25804.1 - 1.6e-10 40.6 0.0 1.9e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 CAR25804.1 - 2.5e-08 33.8 0.0 3.4e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CAR25804.1 - 1.6e-06 27.4 0.0 2.1e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CAR25804.1 - 5.8e-06 25.8 0.0 0.0021 17.5 0.0 2.2 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CAR25804.1 - 9.7e-06 24.9 0.0 1.6e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 CAR25804.1 - 1.2e-05 25.7 0.0 1.8e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 CAR25804.1 - 0.005 16.0 0.0 0.0063 15.7 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 CAR25804.1 - 0.016 14.4 0.0 0.099 11.8 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function, DUF258 cobW PF02492.14 CAR25804.1 - 0.048 13.1 0.0 4.1 6.7 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DRMBL PF07522.9 CAR25805.1 - 2.8e-25 88.4 0.6 5.3e-25 87.6 0.4 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 CAR25805.1 - 1.1e-06 28.3 0.8 2e-06 27.5 0.1 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CAR25805.1 - 0.0041 16.7 2.3 0.01 15.4 1.5 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily GATA PF00320.22 CAR25806.1 - 7.8e-15 53.9 2.1 1.6e-14 52.8 1.4 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF2031 PF09592.5 CAR25806.1 - 0.097 11.8 0.7 0.17 10.9 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) PAT1 PF09770.4 CAR25806.1 - 4.7 5.3 36.8 6.5 4.8 25.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CLTH PF10607.4 CAR25807.1 - 3.1e-23 82.0 0.1 7.6e-23 80.8 0.0 1.6 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain PLC-beta_C PF08703.5 CAR25808.1 - 0.062 12.9 0.4 0.1 12.3 0.3 1.3 1 0 0 1 1 1 0 PLC-beta C terminal AKAP2_C PF15304.1 CAR25809.1 - 0.95 9.0 9.7 1.1 8.7 6.8 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus Macoilin PF09726.4 CAR25809.1 - 1.1 7.5 18.7 1.3 7.2 13.0 1.0 1 0 0 1 1 1 0 Transmembrane protein SRP1_TIP1 PF00660.12 CAR25810.1 - 7e-09 35.4 0.8 1e-08 34.9 0.1 1.6 2 0 0 2 2 2 1 Seripauperin and TIP1 family Meiotic_rec114 PF03525.9 CAR25811.1 - 1.3e-08 33.7 11.9 1e-07 30.8 8.2 2.5 1 1 0 1 1 1 1 Meiotic recombination protein rec114 DUF814 PF05670.8 CAR25812.1 - 3.2e-16 58.9 0.0 6e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF814) WD40 PF00400.27 CAR25813.1 - 7.1e-20 70.0 7.8 5.5e-07 29.2 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CAR25813.1 - 4e-18 65.0 0.1 1.3e-17 63.4 0.0 2.0 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex RIC1 PF07064.8 CAR25814.1 - 2.9e-15 56.4 0.3 6e-15 55.3 0.2 1.5 1 0 0 1 1 1 1 RIC1 COX6B PF02297.12 CAR25815.1 - 6.4e-21 74.1 4.4 7.3e-21 73.9 3.1 1.0 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 CAR25815.1 - 0.27 10.6 2.3 0.67 9.4 1.6 1.7 1 1 0 1 1 1 0 APOBEC-like C-terminal domain UPF0203 PF05254.7 CAR25815.1 - 0.65 9.8 4.8 1.9 8.4 0.9 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) HAD_2 PF13419.1 CAR25816.1 - 5.6e-17 62.5 0.0 1.1e-16 61.5 0.0 1.5 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CAR25816.1 - 6.7e-08 32.1 0.0 1.4e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CAR25816.1 - 0.0011 19.3 0.0 0.035 14.5 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Sep15_SelM PF08806.6 CAR25816.1 - 0.013 15.2 0.0 0.035 13.8 0.0 1.7 1 0 0 1 1 1 0 Sep15/SelM redox domain HATPase_c_3 PF13589.1 CAR25817.1 - 1.1e-11 44.5 0.1 4e-11 42.7 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CAR25817.1 - 2.4e-08 33.6 0.0 5.4e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 CAR25817.1 - 5.5e-08 32.2 0.0 1.1e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain DUF1918 PF08940.6 CAR25818.1 - 0.015 14.6 0.0 66 2.9 0.0 4.6 6 0 0 6 6 6 0 Domain of unknown function (DUF1918) Nramp PF01566.13 CAR25819.1 - 1.2e-93 313.7 17.1 1.7e-93 313.3 11.8 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Bromodomain PF00439.20 CAR25820.1 - 2.9e-06 27.1 0.5 1.1e-05 25.2 0.3 2.0 1 1 0 1 1 1 1 Bromodomain CDC45 PF02724.9 CAR25820.1 - 1.6 6.6 9.0 2.2 6.2 6.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 CAR25820.1 - 2.1 7.6 18.0 4.1 6.6 12.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) HA2 PF04408.18 CAR25821.1 - 2.7e-26 91.5 0.0 1.2e-25 89.4 0.0 2.3 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CAR25821.1 - 6.7e-17 61.3 0.0 5.4e-16 58.4 0.0 2.4 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CAR25821.1 - 7.6e-14 51.3 0.0 4.3e-13 48.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAR25821.1 - 3e-07 30.0 0.0 9.6e-07 28.4 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CAR25821.1 - 2.4e-05 24.4 0.1 9.4e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 CAR25821.1 - 0.01 14.9 0.0 0.031 13.3 0.0 1.8 1 0 0 1 1 1 0 KaiC T2SE PF00437.15 CAR25821.1 - 0.012 14.5 0.0 0.033 13.0 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein PhoH PF02562.11 CAR25821.1 - 0.053 12.7 0.2 0.15 11.2 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein HTH_37 PF13744.1 CAR25821.1 - 0.3 10.9 4.5 0.2 11.4 0.6 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain MOZ_SAS PF01853.13 CAR25822.1 - 1.1e-61 207.3 2.9 1.4e-61 207.0 2.0 1.1 1 0 0 1 1 1 1 MOZ/SAS family Asp PF00026.18 CAR25822.1 - 0.1 11.7 0.2 0.15 11.2 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic aspartyl protease SNF2_N PF00176.18 CAR25823.1 - 1.7e-63 214.1 0.1 2.5e-63 213.6 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 CAR25823.1 - 6.5e-15 54.9 0.0 1.7e-14 53.6 0.0 1.8 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 CAR25823.1 - 1.9e-12 46.8 0.0 5.3e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 CAR25823.1 - 3.4e-07 29.9 11.2 6.4e-07 29.1 7.7 1.5 1 0 0 1 1 1 1 Ring finger domain DEAD PF00270.24 CAR25823.1 - 3.4e-06 26.6 0.0 9.9e-06 25.1 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_3 PF13920.1 CAR25823.1 - 1e-05 25.0 9.5 1.8e-05 24.2 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAR25823.1 - 1.5e-05 24.9 12.1 2.9e-05 23.9 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAR25823.1 - 2.3e-05 23.9 12.7 4.6e-05 23.0 8.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.10 CAR25823.1 - 4.4e-05 23.3 0.0 0.00012 21.9 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 CAR25823.1 - 0.00024 20.6 14.2 0.00048 19.7 9.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CAR25823.1 - 0.15 11.9 2.9 0.33 10.8 2.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CAR25823.1 - 0.15 12.1 5.1 0.33 11.1 3.5 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CAR25823.1 - 0.26 11.0 7.2 0.81 9.4 5.0 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 CAR25823.1 - 0.4 10.2 9.9 0.85 9.2 6.9 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 CAR25823.1 - 1.5 8.7 12.5 3.1 7.7 8.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF3827 PF12877.2 CAR25824.1 - 0.12 10.4 3.8 0.18 9.8 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF1198 PF06711.6 CAR25824.1 - 0.3 10.9 2.1 3.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1198) MIF4G_like PF09088.6 CAR25825.1 - 2e-58 196.9 1.5 6.9e-58 195.2 1.0 1.9 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 CAR25825.1 - 2.3e-48 164.6 3.7 2.7e-48 164.4 1.6 1.9 2 0 0 2 2 2 1 MIF4G like BLOC1_2 PF10046.4 CAR25825.1 - 0.47 10.6 4.0 0.59 10.2 0.2 2.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Pkr1 PF08636.5 CAR25827.1 - 6e-29 99.9 7.1 7.6e-29 99.5 4.9 1.1 1 0 0 1 1 1 1 ER protein Pkr1 Peroxin-13_N PF04088.8 CAR25827.1 - 0.0025 17.8 0.1 0.0035 17.3 0.1 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region PufQ PF05398.6 CAR25827.1 - 0.0025 17.7 0.0 0.0051 16.8 0.0 1.5 1 0 0 1 1 1 1 PufQ cytochrome subunit TMEM192 PF14802.1 CAR25827.1 - 0.008 15.0 0.4 0.012 14.4 0.3 1.3 1 0 0 1 1 1 1 TMEM192 family DUF2417 PF10329.4 CAR25827.1 - 0.011 15.1 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 0 Region of unknown function (DUF2417) LMF1 PF06762.9 CAR25827.1 - 0.015 14.0 0.1 0.017 13.8 0.0 1.0 1 0 0 1 1 1 0 Lipase maturation factor Ni_hydr_CYTB PF01292.15 CAR25827.1 - 0.017 14.5 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 DUF2681 PF10883.3 CAR25827.1 - 0.018 15.2 0.9 0.018 15.2 0.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) Acyltransferase PF01553.16 CAR25827.1 - 0.029 13.8 0.0 0.034 13.5 0.0 1.1 1 0 0 1 1 1 0 Acyltransferase DUF1183 PF06682.7 CAR25827.1 - 0.045 13.3 0.0 0.053 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) TRAP_alpha PF03896.11 CAR25827.1 - 0.049 12.6 0.3 0.065 12.2 0.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4131 PF13567.1 CAR25827.1 - 0.06 12.7 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Ctr PF04145.10 CAR25827.1 - 0.1 12.6 0.3 0.13 12.3 0.2 1.2 1 0 0 1 1 1 0 Ctr copper transporter family PIG-P PF08510.7 CAR25827.1 - 0.25 10.9 3.7 2.2 7.9 2.5 2.0 1 1 0 1 1 1 0 PIG-P Kei1 PF08552.6 CAR25827.1 - 0.44 10.1 2.9 0.35 10.4 0.9 1.5 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Ribosomal_L15e PF00827.12 CAR25830.1 - 2.2e-88 294.8 14.1 2.5e-88 294.6 9.8 1.0 1 0 0 1 1 1 1 Ribosomal L15 AICARFT_IMPCHas PF01808.13 CAR25831.1 - 2e-121 404.9 0.0 2.8e-121 404.4 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 CAR25831.1 - 2.2e-24 85.2 0.0 4.8e-24 84.1 0.0 1.6 1 0 0 1 1 1 1 MGS-like domain PBC PF03792.8 CAR25831.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 PBC domain zf-C3HC4_3 PF13920.1 CAR25832.1 - 9e-08 31.6 12.1 1.9e-07 30.6 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CpG_bind_C PF12269.3 CAR25832.1 - 0.03 13.7 0.1 0.049 13.1 0.1 1.2 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain zf-C3HC4_2 PF13923.1 CAR25832.1 - 6.9 6.7 14.8 17 5.5 10.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Transket_pyr PF02779.19 CAR25833.1 - 1.4e-45 155.0 0.0 2.2e-45 154.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CAR25833.1 - 8.8e-39 132.2 0.2 4.1e-38 130.0 0.2 2.0 2 0 0 2 2 2 1 Transketolase, C-terminal domain Acatn PF13000.2 CAR25834.1 - 4.8e-245 814.2 13.7 5.4e-245 814.0 9.5 1.0 1 0 0 1 1 1 1 Acetyl-coenzyme A transporter 1 Scs3p PF10261.4 CAR25835.1 - 4.5e-68 228.8 7.0 5.8e-68 228.4 4.8 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Med31 PF05669.7 CAR25836.1 - 3.9e-33 113.2 0.4 4.4e-33 113.0 0.3 1.1 1 0 0 1 1 1 1 SOH1 W2 PF02020.13 CAR25837.1 - 9.9e-15 54.2 7.8 9.9e-15 54.2 5.4 2.5 1 1 1 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 CAR25837.1 - 1.7e-12 46.2 21.2 1.6e-06 27.3 1.7 4.3 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 CAR25837.1 - 1e-07 31.5 0.0 3.1e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 CAR25837.1 - 0.0012 18.9 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 CAR25837.1 - 0.002 17.6 18.6 0.0079 15.7 3.3 3.2 1 1 2 3 3 3 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 CAR25837.1 - 0.03 12.9 3.3 0.024 13.2 0.9 1.9 2 1 0 2 2 2 0 L-fucokinase Ras PF00071.17 CAR25838.1 - 1.8e-50 170.5 0.0 2.1e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR25838.1 - 2.3e-13 50.6 0.0 3.1e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAR25838.1 - 6.6e-07 28.7 0.0 8.7e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Cpn60_TCP1 PF00118.19 CAR25839.1 - 9.2e-144 479.6 15.0 1e-143 479.4 10.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Fungal_trans_2 PF11951.3 CAR25840.1 - 1.4e-12 46.9 0.3 1.4e-12 46.9 0.2 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR25840.1 - 4.8e-08 32.7 12.3 8.5e-08 31.9 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aha1_N PF09229.6 CAR25841.1 - 1.6e-36 125.1 0.3 4.8e-36 123.6 0.0 1.9 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 CAR25841.1 - 4.1e-11 43.0 0.1 6.7e-11 42.3 0.1 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Pox_A12 PF04651.8 CAR25841.1 - 0.039 14.0 1.0 0.061 13.4 0.7 1.2 1 0 0 1 1 1 0 Poxvirus A12 protein Hydrolase_6 PF13344.1 CAR25842.1 - 5.1e-23 80.8 0.0 1.2e-22 79.6 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CAR25842.1 - 6.7e-12 44.9 0.0 1.8e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like zf-H2C2_2 PF13465.1 CAR25843.1 - 1.1e-07 31.7 10.6 8.1e-07 29.0 4.4 2.9 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 CAR25843.1 - 3.2e-07 30.2 18.6 7.2e-05 22.8 1.1 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CAR25843.1 - 7.4e-07 29.0 13.7 0.0049 17.1 1.9 3.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 CAR25843.1 - 0.0022 18.1 3.8 1.4 9.2 0.3 3.0 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CAR25843.1 - 0.38 10.9 4.8 1.6 8.9 0.3 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF3439 PF11921.3 CAR25843.1 - 0.82 9.4 8.5 2.8 7.6 5.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) zf-C2H2_6 PF13912.1 CAR25843.1 - 2.4 8.1 10.8 0.48 10.3 0.4 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger Rad9_Rad53_bind PF08605.5 CAR25844.1 - 4.4e-39 133.2 0.3 1.1e-38 131.9 0.2 1.7 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.21 CAR25844.1 - 4.3e-07 29.9 1.0 2.4e-06 27.6 0.0 2.8 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain RNase_P_Rpp14 PF01900.14 CAR25845.1 - 0.026 14.4 0.0 0.065 13.1 0.0 1.7 1 0 0 1 1 1 0 Rpp14/Pop5 family Septin PF00735.13 CAR25846.1 - 2.5e-72 243.2 0.1 3.8e-72 242.6 0.1 1.2 1 0 0 1 1 1 1 Septin Dynamin_N PF00350.18 CAR25846.1 - 0.019 14.7 0.4 0.15 11.8 0.0 2.2 2 0 0 2 2 2 0 Dynamin family Glutaredoxin2_C PF04399.8 CAR25846.1 - 0.067 12.7 0.3 0.72 9.4 0.1 2.5 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain AAA_24 PF13479.1 CAR25846.1 - 0.089 12.3 0.1 0.42 10.1 0.0 2.2 3 0 0 3 3 3 0 AAA domain Sec2p PF06428.6 CAR25846.1 - 0.29 10.9 2.8 6.5 6.6 0.1 3.0 3 0 0 3 3 3 0 GDP/GTP exchange factor Sec2p F-box-like PF12937.2 CAR25848.1 - 0.00024 20.7 0.0 0.00044 19.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CAR25848.1 - 0.0036 16.9 1.8 0.0052 16.4 0.1 2.1 3 0 0 3 3 3 1 F-box domain PRKCSH-like PF12999.2 CAR25849.1 - 3.3e-39 134.2 1.2 8.9e-39 132.8 0.8 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 CAR25849.1 - 4.4e-18 65.2 6.2 1.3e-16 60.4 4.3 2.8 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 CAR25849.1 - 0.00042 21.0 0.2 0.0012 19.5 0.1 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.13 CAR25849.1 - 0.0014 18.5 15.3 0.014 15.3 3.7 2.6 1 1 1 2 2 2 2 Low-density lipoprotein receptor domain class A DIT1_PvcA PF05141.7 CAR25849.1 - 0.0017 17.7 2.1 0.0025 17.1 0.5 2.1 2 1 0 2 2 2 1 Pyoverdine/dityrosine biosynthesis protein ATG27 PF09451.5 CAR25849.1 - 0.0055 15.9 0.1 0.013 14.7 0.0 1.6 1 0 0 1 1 1 1 Autophagy-related protein 27 DUF2400 PF09674.5 CAR25849.1 - 0.053 13.2 1.4 10 5.7 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2400) RNase_E_G PF10150.4 CAR25849.1 - 0.27 10.4 5.3 4.1 6.5 0.4 2.5 2 0 0 2 2 2 0 Ribonuclease E/G family Snapin_Pallidin PF14712.1 CAR25849.1 - 1.3 9.4 6.5 0.35 11.2 0.7 2.7 3 0 0 3 3 3 0 Snapin/Pallidin TMF_DNA_bd PF12329.3 CAR25849.1 - 1.6 8.6 8.3 9.3 6.1 0.3 3.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Svf1 PF08622.5 CAR25850.1 - 3.9e-89 298.8 0.3 4.7e-89 298.5 0.2 1.1 1 0 0 1 1 1 1 Svf1-like CRF1 PF10380.4 CAR25852.1 - 8.1e-35 119.8 2.9 8.1e-35 119.8 2.0 5.9 5 2 1 6 6 6 1 Transcription factor CRF1 WD40 PF00400.27 CAR25853.1 - 4.2e-65 213.4 21.5 8.6e-09 34.9 0.0 11.8 11 1 1 12 12 12 9 WD domain, G-beta repeat Utp13 PF08625.6 CAR25853.1 - 7.4e-48 161.7 1.4 1.2e-47 161.0 0.9 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 CAR25853.1 - 5.1e-08 31.5 6.3 0.0006 18.0 0.0 6.0 4 2 3 7 7 7 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CAR25853.1 - 6.7e-05 21.8 5.5 0.013 14.3 0.0 4.1 2 1 1 4 4 4 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 CAR25853.1 - 0.00071 17.9 0.1 1.5 7.0 0.0 3.3 3 1 1 4 4 4 2 Cytochrome D1 heme domain Coatomer_WDAD PF04053.9 CAR25853.1 - 0.00081 18.2 1.1 0.049 12.4 0.0 2.4 2 0 0 2 2 2 2 Coatomer WD associated region eIF2A PF08662.6 CAR25853.1 - 0.02 14.5 0.6 3.5 7.3 0.0 3.3 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Rsa3 PF14615.1 CAR25854.1 - 6.2e-20 70.2 0.3 1e-19 69.5 0.2 1.4 1 0 0 1 1 1 1 Ribosome-assembly protein 3 DndB PF14072.1 CAR25854.1 - 4.6e-07 29.3 1.1 5.9e-07 28.9 0.8 1.1 1 0 0 1 1 1 1 DNA-sulfur modification-associated Fusion_gly PF00523.13 CAR25854.1 - 0.00081 17.5 0.8 0.0011 17.1 0.5 1.2 1 0 0 1 1 1 1 Fusion glycoprotein F0 YbaB_DNA_bd PF02575.11 CAR25854.1 - 0.16 11.8 0.1 0.16 11.8 0.1 2.4 3 0 0 3 3 3 0 YbaB/EbfC DNA-binding family DUF4551 PF15087.1 CAR25854.1 - 3.9 5.7 12.8 5 5.3 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF4613 PF15390.1 CAR25854.1 - 5 5.1 7.9 6.2 4.8 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF572 PF04502.8 CAR25854.1 - 5.5 6.1 16.2 6.7 5.8 11.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) VIT1 PF01988.14 CAR25855.1 - 2.4e-58 197.1 0.8 3.4e-58 196.6 0.6 1.2 1 0 0 1 1 1 1 VIT family Histone PF00125.19 CAR25856.1 - 5.1e-21 74.5 0.3 6.8e-21 74.1 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CAR25856.1 - 1.6e-05 24.8 0.1 3.4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CAR25856.1 - 0.0037 17.5 0.0 0.0062 16.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Mitofilin PF09731.4 CAR25856.1 - 0.033 12.8 2.7 0.039 12.6 1.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Herpes_glycop_H PF02489.11 CAR25856.1 - 0.063 11.2 0.3 0.063 11.2 0.2 1.0 1 0 0 1 1 1 0 Herpesvirus glycoprotein H ImcF-related_N PF14331.1 CAR25856.1 - 0.11 11.3 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 ImcF-related N-terminal domain Histone PF00125.19 CAR25857.1 - 5.6e-26 90.4 0.0 7.2e-26 90.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CAR25857.1 - 2.4e-06 27.5 0.0 3.4e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Atg14 PF10186.4 CAR25860.1 - 0.055 12.3 19.6 0.16 10.9 13.1 2.0 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 YebO PF13974.1 CAR25860.1 - 4.6 7.1 10.6 4.6 7.1 0.1 3.0 2 0 0 2 2 2 0 YebO-like protein CFIA_Pcf11 PF11526.3 CAR25861.1 - 2.5e-25 88.4 0.6 2.5e-25 88.4 0.4 2.6 2 0 0 2 2 2 1 Subunit of cleavage factor IA Pcf11 EIF4E-T PF10477.4 CAR25861.1 - 0.013 14.3 13.0 0.0047 15.8 7.2 1.6 2 0 0 2 2 2 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E ZYG-11_interact PF05884.7 CAR25861.1 - 0.043 12.9 4.3 0.07 12.1 3.0 1.4 1 0 0 1 1 1 0 Interactor of ZYG-11 AIF_C PF14721.1 CAR25861.1 - 0.048 13.9 2.6 0.12 12.6 1.8 1.6 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term zf-RING_2 PF13639.1 CAR25861.1 - 0.048 13.4 0.2 0.33 10.7 0.0 2.4 2 0 0 2 2 2 0 Ring finger domain SPX PF03105.14 CAR25861.1 - 0.1 12.3 9.8 0.2 11.4 6.8 1.4 1 0 0 1 1 1 0 SPX domain zf-H2C2_2 PF13465.1 CAR25861.1 - 0.98 9.8 6.8 15 6.1 0.1 3.7 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.1 CAR25861.1 - 1.6 9.2 8.2 1.2 9.6 0.2 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger Mito_carr PF00153.22 CAR25862.1 - 5.8e-32 109.2 0.5 2.1e-15 56.1 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Sugar_tr PF00083.19 CAR25863.1 - 1.9e-97 326.6 18.8 2.3e-97 326.4 13.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR25863.1 - 5.6e-29 100.9 44.6 3.7e-28 98.2 15.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CAR25863.1 - 4.5e-06 25.3 18.6 0.00075 17.9 0.6 2.5 3 0 0 3 3 3 2 MFS/sugar transport protein DNA_binding_1 PF01035.15 CAR25864.1 - 5.1e-26 90.2 0.0 7.5e-26 89.7 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Methyltransf_4 PF02390.12 CAR25865.1 - 5.4e-61 205.1 0.1 7.6e-61 204.6 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 CAR25865.1 - 4.4e-06 26.3 0.1 1.7e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR25865.1 - 1.8e-05 25.2 0.0 0.00038 20.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CAR25865.1 - 0.0012 18.9 0.0 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAR25865.1 - 0.0019 18.6 0.0 0.016 15.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CAR25865.1 - 0.0049 16.2 0.0 0.014 14.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain FmrO PF07091.6 CAR25865.1 - 0.016 14.2 0.0 0.031 13.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Ubie_methyltran PF01209.13 CAR25865.1 - 0.023 13.8 0.0 0.064 12.3 0.0 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 CAR25865.1 - 0.023 15.0 0.0 0.087 13.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain DOT1 PF08123.8 CAR25865.1 - 0.043 13.1 0.0 0.16 11.2 0.0 1.8 1 1 1 2 2 2 0 Histone methylation protein DOT1 Ribosomal_L10 PF00466.15 CAR25866.1 - 1.2e-11 44.3 0.0 1.9e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Peptidase_C97 PF05903.9 CAR25867.1 - 0.031 14.0 0.1 0.049 13.3 0.1 1.3 1 0 0 1 1 1 0 PPPDE putative peptidase domain Luciferase_3H PF10284.4 CAR25867.1 - 0.061 13.2 1.1 0.18 11.7 0.2 2.1 2 0 0 2 2 2 0 Luciferase helical bundle domain DUF3767 PF12597.3 CAR25868.1 - 9.3e-44 147.8 0.3 1.3e-43 147.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) DUF4131 PF13567.1 CAR25868.1 - 0.056 12.8 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3353 PF11833.3 CAR25868.1 - 0.28 10.6 1.9 0.17 11.3 0.1 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3353) Sel1 PF08238.7 CAR25869.1 - 7.5e-38 128.1 22.0 1.9e-06 28.3 0.2 8.0 7 1 0 7 7 7 7 Sel1 repeat DUF605 PF04652.11 CAR25869.1 - 2.2 7.6 15.7 3.1 7.0 10.9 1.2 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 CAR25869.1 - 3.5 5.7 11.9 4.7 5.3 8.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Aminotran_1_2 PF00155.16 CAR25870.1 - 3.6e-72 243.2 0.0 4.5e-72 243.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 CAR25870.1 - 9.6e-09 33.9 0.0 1.6e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 CAR25870.1 - 4.3e-06 25.7 0.0 4.3e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 CAR25870.1 - 0.0016 17.5 0.2 0.27 10.2 0.0 2.2 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Reticulon PF02453.12 CAR25871.1 - 1.3e-36 125.7 2.9 1.8e-36 125.3 2.0 1.2 1 0 0 1 1 1 1 Reticulon OHCU_decarbox PF09349.5 CAR25871.1 - 0.65 10.2 3.2 3.2 8.0 1.2 2.6 2 1 0 2 2 2 0 OHCU decarboxylase Aconitase PF00330.15 CAR25872.1 - 3e-69 233.7 0.0 6.1e-43 146.9 0.0 2.2 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CAR25872.1 - 9e-28 96.9 0.2 2e-27 95.9 0.0 1.6 2 0 0 2 2 2 1 Aconitase C-terminal domain Porphobil_deam PF01379.15 CAR25873.1 - 1.6e-85 285.4 0.0 2.1e-85 285.0 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 CAR25873.1 - 5.1e-19 68.1 0.2 8.9e-19 67.3 0.2 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Na_Ca_ex PF01699.19 CAR25875.1 - 1.8e-48 163.6 27.3 5.6e-25 87.5 4.8 3.0 2 1 1 3 3 3 2 Sodium/calcium exchanger protein Flavokinase PF01687.12 CAR25876.1 - 2.3e-29 101.7 0.0 3e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase GLE1 PF07817.8 CAR25877.1 - 8.2e-88 293.6 0.6 8.2e-88 293.6 0.4 2.0 2 0 0 2 2 1 1 GLE1-like protein CAF-1_p150 PF11600.3 CAR25877.1 - 0.0006 19.2 28.8 0.0006 19.2 20.0 1.6 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal MAP7 PF05672.6 CAR25877.1 - 0.0011 18.3 32.2 0.0011 18.3 22.3 1.6 2 0 0 2 2 2 1 MAP7 (E-MAP-115) family CompInhib_SCIN PF11546.3 CAR25877.1 - 0.043 13.6 0.9 0.12 12.2 0.1 2.2 2 0 0 2 2 2 0 Staphylococcal complement inhibitor SCIN CDC45 PF02724.9 CAR25877.1 - 0.21 9.5 17.0 0.068 11.1 9.9 1.5 2 0 0 2 2 2 0 CDC45-like protein LMBR1 PF04791.11 CAR25877.1 - 0.21 10.1 2.2 0.29 9.6 1.5 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein U79_P34 PF03064.11 CAR25877.1 - 0.32 10.4 19.0 0.57 9.6 13.2 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF4407 PF14362.1 CAR25877.1 - 0.47 9.3 15.8 0.79 8.6 10.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SprA-related PF12118.3 CAR25877.1 - 1.5 8.1 25.6 2.3 7.4 17.7 1.3 1 0 0 1 1 1 0 SprA-related family Ndc1_Nup PF09531.5 CAR25877.1 - 4.8 5.4 8.2 8.6 4.6 5.7 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Asp-B-Hydro_N PF05279.6 CAR25877.1 - 7.8 6.2 23.7 0.64 9.8 13.2 1.6 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region Ribosomal_L5_C PF00673.16 CAR25878.1 - 7.2e-23 80.1 0.0 4.4e-22 77.6 0.0 2.2 2 1 1 3 3 3 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 CAR25878.1 - 2.3e-05 24.0 0.0 5.3e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L5 MRP-S33 PF08293.6 CAR25879.1 - 2.1e-30 104.5 0.1 2.6e-30 104.2 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 DUF4023 PF13215.1 CAR25879.1 - 0.21 11.3 0.4 0.21 11.3 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4023) Gpi1 PF05024.10 CAR25880.1 - 3.9e-54 183.2 15.7 3.9e-54 183.2 10.9 2.1 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) XRCC4 PF06632.7 CAR25880.1 - 0.26 10.1 0.0 0.36 9.6 0.0 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Ion_trans PF00520.26 CAR25881.1 - 4.2e-97 323.2 106.3 5.3e-36 123.7 2.4 6.2 6 1 0 6 6 6 4 Ion transport protein PKD_channel PF08016.7 CAR25881.1 - 4.7e-06 25.2 3.4 4.7e-06 25.2 2.4 8.9 8 2 2 10 10 10 5 Polycystin cation channel GDPD PF03009.12 CAR25882.1 - 1.9e-81 273.3 0.3 3.5e-81 272.4 0.2 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family SPX PF03105.14 CAR25882.1 - 7.3e-36 124.3 12.8 7.3e-36 124.3 8.9 3.1 2 1 0 2 2 2 1 SPX domain Ank_2 PF12796.2 CAR25882.1 - 4e-25 87.9 0.9 8.6e-13 48.4 0.0 4.4 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.25 CAR25882.1 - 4.4e-23 79.8 7.2 0.003 17.2 0.1 7.1 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 CAR25882.1 - 1.3e-19 70.2 0.3 1.8e-08 34.6 0.0 4.7 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CAR25882.1 - 1.2e-13 49.8 3.4 0.28 11.5 0.0 7.6 8 0 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.1 CAR25882.1 - 1.5e-12 47.2 2.0 0.036 14.3 0.0 5.9 3 1 4 7 7 7 5 Ankyrin repeats (many copies) MBD_C PF14048.1 CAR25882.1 - 0.96 10.0 4.1 2.6 8.6 0.0 2.9 3 0 0 3 3 3 0 C-terminal domain of methyl-CpG binding protein 2 and 3 ABC1 PF03109.11 CAR25883.1 - 5.3e-21 74.8 0.0 1.3e-20 73.4 0.0 1.7 1 0 0 1 1 1 1 ABC1 family KaiC PF06745.8 CAR25883.1 - 0.065 12.3 0.1 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 KaiC APH PF01636.18 CAR25883.1 - 0.17 11.6 0.0 0.94 9.1 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Arf PF00025.16 CAR25884.1 - 4.4e-75 250.7 0.1 5e-75 250.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CAR25884.1 - 1.1e-11 44.3 0.0 1.2e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CAR25884.1 - 7.1e-11 41.7 0.0 8.1e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CAR25884.1 - 3.5e-10 39.1 0.3 1.4e-06 27.3 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CAR25884.1 - 4.4e-10 39.1 0.0 5.3e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CAR25884.1 - 2.5e-09 37.6 0.0 3.5e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 CAR25884.1 - 2.7e-05 23.6 0.3 0.0004 19.8 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 CAR25884.1 - 0.00051 20.3 0.3 0.002 18.4 0.2 1.7 1 1 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.18 CAR25884.1 - 0.00055 19.8 0.0 0.001 18.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase ArgK PF03308.11 CAR25884.1 - 0.002 16.9 1.9 0.14 10.9 0.4 2.9 2 1 0 2 2 2 1 ArgK protein SRP54 PF00448.17 CAR25884.1 - 0.074 12.4 0.3 0.55 9.6 0.1 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain EBV-NA3 PF05009.7 CAR25885.1 - 0.00042 19.6 0.0 0.00058 19.1 0.0 1.2 1 0 0 1 1 1 1 Epstein-Barr virus nuclear antigen 3 (EBNA-3) PDH PF02153.12 CAR25886.1 - 3.9e-13 48.8 0.1 5.9e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 CAR25886.1 - 5.8e-06 26.2 0.0 1.2e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 CAR25886.1 - 3.5e-05 24.1 0.0 7e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 CAR25886.1 - 7.8e-05 21.8 0.0 0.00015 20.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 CAR25886.1 - 0.00052 19.4 0.0 0.0011 18.4 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 CAR25886.1 - 0.004 16.8 0.0 0.0078 15.8 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.4 CAR25886.1 - 0.016 14.8 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Rossmann-like domain UDPG_MGDP_dh_N PF03721.9 CAR25886.1 - 0.02 14.2 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 CAR25886.1 - 0.02 14.8 0.0 0.054 13.4 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Ureidogly_hydro PF04115.7 CAR25887.1 - 4.4e-45 152.9 0.0 5.4e-45 152.7 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate hydrolase TPR_10 PF13374.1 CAR25888.1 - 0.065 13.1 0.2 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Rpp20 PF12328.3 CAR25889.1 - 7e-27 93.8 1.6 8.1e-25 87.1 1.1 2.1 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 CAR25889.1 - 4.1e-14 51.9 0.2 6e-14 51.3 0.1 1.3 1 0 0 1 1 1 1 Alba AA_kinase PF00696.23 CAR25889.1 - 0.05 13.1 0.0 0.052 13.0 0.0 1.2 1 0 0 1 1 1 0 Amino acid kinase family Pex24p PF06398.6 CAR25890.1 - 1.1e-38 132.9 8.7 1.4e-38 132.6 6.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3810 PF12725.2 CAR25890.1 - 0.018 13.9 0.4 0.028 13.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Oxidored-like PF09791.4 CAR25891.1 - 1.9e-26 91.2 1.3 3.6e-26 90.3 0.9 1.5 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal Pox_Ag35 PF03286.9 CAR25891.1 - 0.013 15.0 4.5 0.021 14.3 3.1 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein HSP70 PF00012.15 CAR25892.1 - 1.5e-179 597.7 0.5 1.5e-179 597.7 0.4 1.8 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 CAR25892.1 - 6.8e-10 38.0 0.0 3.3e-09 35.7 0.0 1.8 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 CAR25892.1 - 6.6e-06 25.9 2.1 0.00012 21.8 0.6 3.1 2 1 0 2 2 2 1 Cell division protein FtsA Trans_reg_C PF00486.23 CAR25892.1 - 0.021 14.7 0.1 0.074 12.9 0.0 1.9 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal DnaB_bind PF10410.4 CAR25892.1 - 0.089 12.8 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase Endonuc_Holl PF10107.4 CAR25892.1 - 0.5 10.0 9.2 0.17 11.5 0.2 2.5 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Aa_trans PF01490.13 CAR25893.1 - 3.8e-91 305.6 29.0 4.4e-91 305.3 20.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Claudin_2 PF13903.1 CAR25893.1 - 0.00016 21.3 0.5 0.82 9.3 0.0 2.8 3 0 0 3 3 3 2 PMP-22/EMP/MP20/Claudin tight junction AA_permease_2 PF13520.1 CAR25893.1 - 4 5.8 36.4 0.03 12.8 17.0 2.0 1 1 1 2 2 2 0 Amino acid permease AAA PF00004.24 CAR25894.1 - 1.1e-40 138.8 0.0 4.1e-40 137.0 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CAR25894.1 - 8e-06 26.0 0.0 0.00099 19.2 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 CAR25894.1 - 3.5e-05 23.5 0.0 0.00016 21.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CAR25894.1 - 8.6e-05 22.5 0.0 0.00021 21.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CAR25894.1 - 0.00019 21.4 0.0 0.00047 20.1 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 CAR25894.1 - 0.0012 19.6 0.1 0.0036 18.1 0.0 2.0 2 1 0 2 2 1 1 AAA domain DUF815 PF05673.8 CAR25894.1 - 0.0015 17.5 0.0 0.0026 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 CAR25894.1 - 0.0035 16.4 0.0 0.0064 15.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 CAR25894.1 - 0.01 15.7 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CAR25894.1 - 0.013 15.2 0.2 0.013 15.2 0.1 1.7 2 0 0 2 2 1 0 Part of AAA domain Zeta_toxin PF06414.7 CAR25894.1 - 0.014 14.5 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 CAR25894.1 - 0.018 14.9 0.0 0.04 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CAR25894.1 - 0.02 15.1 0.0 0.057 13.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain Sigma54_activ_2 PF14532.1 CAR25894.1 - 0.022 14.8 0.0 0.046 13.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.1 CAR25894.1 - 0.022 14.6 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CAR25894.1 - 0.027 14.6 0.0 0.06 13.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.12 CAR25894.1 - 0.033 13.5 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.6 CAR25894.1 - 0.036 13.6 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 CAR25894.1 - 0.047 12.8 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 CAR25894.1 - 0.049 12.3 0.0 0.079 11.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_24 PF13479.1 CAR25894.1 - 0.088 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CAR25894.1 - 0.092 12.4 0.0 4.8 6.7 0.0 2.4 1 1 1 2 2 2 0 Archaeal ATPase RNA_pol_Rbc25 PF08292.7 CAR25895.1 - 6.8e-46 155.4 0.3 9.2e-46 155.0 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 CAR25895.1 - 4.2e-22 78.0 0.0 6.4e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 CAR25895.1 - 0.021 14.8 0.0 0.057 13.5 0.0 1.8 1 1 0 1 1 1 0 S1 RNA binding domain LTV PF04180.9 CAR25896.1 - 2.9e-113 379.5 42.4 3.4e-113 379.3 29.4 1.0 1 0 0 1 1 1 1 Low temperature viability protein DUF3294 PF07957.6 CAR25897.1 - 7.5e-82 274.0 1.7 8.4e-82 273.8 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) Transposase_22 PF02994.9 CAR25897.1 - 0.099 11.1 1.2 0.15 10.4 0.8 1.3 1 0 0 1 1 1 0 L1 transposable element Pro-rich_19 PF15455.1 CAR25897.1 - 0.11 11.5 0.5 0.14 11.1 0.3 1.1 1 0 0 1 1 1 0 Proline-rich 19 AF0941-like PF14591.1 CAR25897.1 - 0.41 10.7 7.8 2 8.4 0.6 3.1 2 2 1 3 3 3 0 AF0941-like TBPIP PF07106.8 CAR25897.1 - 0.44 10.0 5.5 0.12 11.9 0.5 2.3 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fib_alpha PF08702.5 CAR25897.1 - 2.8 8.0 7.2 0.96 9.5 3.2 1.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family PUF PF00806.14 CAR25898.1 - 5.1e-34 113.8 2.7 8.6e-05 21.8 0.0 8.3 8 0 0 8 8 8 7 Pumilio-family RNA binding repeat Cpn60_TCP1 PF00118.19 CAR25899.1 - 5.1e-128 427.7 5.9 5.8e-128 427.5 4.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Vps53_N PF04100.7 CAR25900.1 - 6.6e-89 298.3 9.8 1.1e-88 297.6 6.8 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF3724 PF12521.3 CAR25900.1 - 0.19 11.4 1.7 0.29 10.8 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3724) HORMA PF02301.13 CAR25901.1 - 4.4e-44 150.4 0.5 4.9e-44 150.3 0.4 1.0 1 0 0 1 1 1 1 HORMA domain DUF4279 PF14106.1 CAR25901.1 - 0.0063 16.3 0.2 0.32 10.8 0.0 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4279) DUF1682 PF07946.9 CAR25901.1 - 0.077 11.8 0.2 0.085 11.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PPTA PF01239.17 CAR25902.1 - 3.2e-33 111.6 17.4 1.5e-08 33.6 0.0 6.2 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat Cyclin_N PF00134.18 CAR25903.1 - 1.3e-10 40.9 1.1 2.4e-10 40.0 0.8 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.14 CAR25903.1 - 0.091 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcription factor TFIIB repeat DEAD PF00270.24 CAR25904.1 - 2.7e-43 147.3 0.0 1.2e-42 145.2 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 CAR25904.1 - 1.5e-24 85.3 0.1 3.3e-24 84.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 CAR25904.1 - 1.5e-22 79.2 0.1 3.6e-22 77.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 CAR25904.1 - 2.7e-05 24.2 0.8 8e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain FHA PF00498.21 CAR25905.1 - 1.7e-14 53.6 0.0 3.2e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 FHA domain HSP70 PF00012.15 CAR25906.1 - 2.1e-265 881.3 11.8 2.4e-265 881.1 8.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CAR25906.1 - 2.1e-18 66.0 2.3 3.6e-17 61.9 0.3 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 CAR25906.1 - 0.0028 16.8 5.1 0.031 13.3 0.1 3.5 3 1 1 4 4 4 1 Hydantoinase/oxoprolinase DDR PF08841.5 CAR25906.1 - 0.0084 14.9 1.4 0.069 11.9 0.5 2.4 1 1 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.11 CAR25906.1 - 0.021 14.4 0.0 0.2 11.2 0.0 2.3 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.15 CAR25906.1 - 0.023 14.0 0.0 0.2 10.9 0.0 2.3 1 1 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.1 CAR25906.1 - 0.1 12.4 6.8 0.41 10.4 0.8 3.4 2 2 0 2 2 2 0 Cell division protein FtsA Secretin_N PF03958.12 CAR25906.1 - 0.19 11.9 1.7 8.6 6.6 0.0 3.4 4 0 0 4 4 4 0 Bacterial type II/III secretion system short domain DUF883 PF05957.8 CAR25906.1 - 3.5 8.0 6.4 1 9.7 1.0 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) dCMP_cyt_deam_1 PF00383.17 CAR25908.1 - 3.4e-18 65.1 0.0 4.6e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 CAR25908.1 - 0.0085 15.7 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 APOBEC-like N-terminal domain DUF3525 PF12039.3 CAR25908.1 - 0.12 10.8 0.0 0.12 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) Bd3614-deam PF14439.1 CAR25908.1 - 0.12 12.2 0.1 0.24 11.2 0.1 1.6 1 1 0 1 1 1 0 Bd3614-like deaminase PX PF00787.19 CAR25909.1 - 7.7e-25 86.8 0.3 2.4e-24 85.3 0.2 1.9 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 CAR25909.1 - 0.00098 18.4 11.3 0.0041 16.4 1.5 2.4 2 0 0 2 2 2 2 Vps5 C terminal like DUF2937 PF11157.3 CAR25909.1 - 0.036 13.3 0.4 0.35 10.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) FlaC_arch PF05377.6 CAR25909.1 - 0.08 12.8 2.3 3.3 7.6 0.1 3.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.7 CAR25909.1 - 0.26 11.5 2.2 29 5.0 0.4 3.2 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein BAR PF03114.13 CAR25909.1 - 0.38 10.2 13.4 0.81 9.1 9.0 1.7 1 1 0 1 1 1 0 BAR domain DUF1664 PF07889.7 CAR25909.1 - 0.4 10.4 3.7 1.6 8.5 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3552 PF12072.3 CAR25909.1 - 0.66 9.1 9.1 0.73 9.0 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) bZIP_1 PF00170.16 CAR25909.1 - 2.1 8.3 6.9 17 5.4 0.9 3.6 2 1 1 3 3 3 0 bZIP transcription factor DUF972 PF06156.8 CAR25909.1 - 5.1 7.4 9.4 1.3 9.3 0.5 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF972) SPRY PF00622.23 CAR25910.1 - 0.00068 19.7 0.1 0.013 15.5 0.0 2.6 2 0 0 2 2 2 1 SPRY domain T4_tail_cap PF11091.3 CAR25910.1 - 0.095 11.3 1.1 0.14 10.8 0.8 1.2 1 0 0 1 1 1 0 Tail-tube assembly protein Prefoldin PF02996.12 CAR25910.1 - 0.13 11.9 1.2 0.28 10.8 0.9 1.5 1 0 0 1 1 1 0 Prefoldin subunit Fungal_trans PF04082.13 CAR25911.1 - 4.6e-44 150.2 1.8 4.4e-43 147.0 1.2 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR25911.1 - 1.6e-09 37.4 13.1 3e-09 36.6 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NMT1 PF09084.6 CAR25912.1 - 2.2e-77 259.5 0.0 2.6e-77 259.2 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 CAR25912.1 - 4.2e-07 29.6 0.1 0.027 13.8 0.0 2.5 2 1 0 3 3 3 2 NMT1-like family 2Fe-2S_thioredx PF01257.14 CAR25912.1 - 0.015 14.9 0.9 0.025 14.1 0.7 1.3 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin Phosphonate-bd PF12974.2 CAR25912.1 - 0.044 13.1 0.0 0.066 12.5 0.0 1.2 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein GCD14 PF08704.5 CAR25914.1 - 0.0032 16.9 0.0 0.052 13.0 0.0 2.2 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit GCD14_N PF14801.1 CAR25914.1 - 0.11 12.0 0.0 0.39 10.3 0.0 2.0 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term Ribosomal_L24e PF01246.15 CAR25915.1 - 8.5e-30 102.4 1.8 8.5e-30 102.4 1.3 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e TFIIF_alpha PF05793.7 CAR25915.1 - 0.028 12.7 23.6 0.036 12.4 16.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nucleoplasmin PF03066.10 CAR25915.1 - 0.23 10.9 15.8 0.33 10.4 11.0 1.3 1 0 0 1 1 1 0 Nucleoplasmin AAA_23 PF13476.1 CAR25915.1 - 0.4 10.9 17.6 0.48 10.7 12.2 1.2 1 0 0 1 1 1 0 AAA domain YqfQ PF14181.1 CAR25915.1 - 0.83 9.6 14.5 1.7 8.6 10.1 1.5 1 0 0 1 1 1 0 YqfQ-like protein GOLD_2 PF13897.1 CAR25915.1 - 1 9.5 9.4 21 5.3 0.0 2.5 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Mem_trans PF03547.13 CAR25915.1 - 1 7.5 6.7 1.3 7.1 4.6 1.1 1 0 0 1 1 1 0 Membrane transport protein Daxx PF03344.10 CAR25915.1 - 1.1 7.6 19.9 1.3 7.4 13.8 1.1 1 0 0 1 1 1 0 Daxx Family TRAP_alpha PF03896.11 CAR25915.1 - 1.6 7.6 12.2 2.3 7.1 8.4 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Pilt PF15453.1 CAR25915.1 - 2.8 7.5 10.7 3.5 7.2 7.4 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions EBV-NA3 PF05009.7 CAR25915.1 - 4.8 6.3 7.7 7.8 5.6 5.4 1.4 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Pam16 PF03656.8 CAR25916.1 - 2.4e-06 27.3 0.1 3.1e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.26 CAR25916.1 - 9.8e-06 25.2 0.2 1.4e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain SMC_Nse1 PF07574.8 CAR25917.1 - 2.4e-43 148.1 0.0 2.9e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 CAR25917.1 - 9.9e-09 35.0 12.4 9.9e-09 35.0 8.6 2.5 2 0 0 2 2 2 1 RING-like domain C1_1 PF00130.17 CAR25917.1 - 0.67 9.7 13.2 0.075 12.7 5.6 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Myosin_tail_1 PF01576.14 CAR25918.1 - 4.5e-05 21.3 74.9 0.0001 20.1 30.7 2.1 1 1 1 2 2 2 2 Myosin tail DUF904 PF06005.7 CAR25918.1 - 0.002 18.3 26.0 0.0028 17.9 6.4 8.1 5 2 3 8 8 8 3 Protein of unknown function (DUF904) Spc7 PF08317.6 CAR25918.1 - 0.0026 16.4 17.0 0.0026 16.4 11.8 4.0 1 1 3 4 4 4 1 Spc7 kinetochore protein GAS PF13851.1 CAR25918.1 - 0.05 12.7 77.6 0.038 13.1 11.8 5.2 1 1 2 5 5 5 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 CAR25918.1 - 1.4 8.5 67.4 3.4 7.2 9.1 5.3 1 1 4 5 5 5 0 IncA protein Response_reg PF00072.19 CAR25919.1 - 1.4e-19 70.1 0.0 5.5e-13 48.9 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain ABC2_membrane_3 PF12698.2 CAR25919.1 - 0.3 10.0 3.2 0.6 9.0 2.2 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein Ssl1 PF04056.9 CAR25920.1 - 3.4e-84 281.2 0.0 4.5e-84 280.8 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 CAR25920.1 - 9.2e-21 73.6 11.7 9.2e-21 73.6 8.1 2.7 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 CAR25920.1 - 1.5e-10 41.4 0.0 2.2e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 CAR25920.1 - 0.0048 16.6 0.0 0.0092 15.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Taeniidae_ag PF05596.6 CAR25920.1 - 0.043 13.6 0.0 0.093 12.5 0.0 1.6 1 0 0 1 1 1 0 Taeniidae antigen CDC45 PF02724.9 CAR25920.1 - 0.36 8.7 12.2 0.47 8.4 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DUP PF00674.13 CAR25921.1 - 2.5e-06 27.4 0.2 2.5e-06 27.4 0.2 2.3 2 1 1 3 3 3 1 DUP family DUP PF00674.13 CAR25922.1 - 5.3e-07 29.5 0.2 5.3e-07 29.5 0.1 2.3 2 0 0 2 2 2 1 DUP family PspB PF06667.7 CAR25922.1 - 4.4 7.3 5.1 7.8 6.5 0.0 2.6 2 0 0 2 2 2 0 Phage shock protein B DUP PF00674.13 CAR25923.1 - 1.6e-06 28.0 0.2 1.6e-06 28.0 0.1 2.2 2 1 1 3 3 3 1 DUP family DUP PF00674.13 CAR25924.1 - 6e-07 29.3 0.2 6e-07 29.3 0.2 2.6 3 1 0 3 3 3 1 DUP family SMP_2 PF10144.4 CAR25924.1 - 0.018 14.1 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin DUP PF00674.13 CAR25925.1 - 1.7e-05 24.7 0.5 1.7e-05 24.7 0.3 2.1 2 1 0 2 2 2 1 DUP family MFS_1 PF07690.11 CAR25927.1 - 8.4e-35 120.1 24.5 1.1e-34 119.6 17.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily CMS1 PF14617.1 CAR25928.1 - 1e-21 77.1 12.8 3.9e-21 75.2 8.9 1.8 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit VitD-bind_III PF09164.5 CAR25928.1 - 0.0056 16.2 0.5 0.034 13.7 0.0 2.5 2 1 1 3 3 3 1 Vitamin D binding protein, domain III Merozoite_SPAM PF07133.6 CAR25928.1 - 0.63 9.9 19.7 0.1 12.4 10.8 1.7 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) CDC45 PF02724.9 CAR25928.1 - 2.5 6.0 12.0 3.4 5.5 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Adaptin_N PF01602.15 CAR25929.1 - 4e-90 302.6 13.8 5e-90 302.3 9.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 CAR25929.1 - 6.7e-07 29.5 2.2 0.0035 17.5 0.0 3.9 3 1 1 4 4 4 2 HEAT repeats DUF2435 PF10363.4 CAR25929.1 - 0.0011 18.8 0.5 0.0071 16.2 0.1 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) Arm PF00514.18 CAR25929.1 - 0.013 15.3 0.0 8.9 6.3 0.0 3.8 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Candida_ALS_N PF11766.3 CAR25930.1 - 2.6e-69 232.9 8.1 2.6e-69 232.9 5.6 3.9 4 2 0 4 4 4 1 Cell-wall agglutinin N-terminal ligand-sugar binding Flocculin PF00624.13 CAR25930.1 - 6e-31 106.0 197.9 2.8e-08 33.4 21.5 14.9 13 3 2 15 15 15 7 Flocculin repeat Spore_coat_CotO PF14153.1 CAR25931.1 - 0.0018 17.7 8.7 0.0018 17.7 6.0 2.2 3 0 0 3 3 3 1 Spore coat protein CotO Ycf1 PF05758.7 CAR25931.1 - 0.0043 14.8 3.5 0.0073 14.0 2.4 1.3 1 0 0 1 1 1 1 Ycf1 EIIBC-GUT_N PF03612.9 CAR25931.1 - 0.071 12.7 3.6 0.14 11.7 2.5 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus FLO_LFY PF01698.11 CAR25931.1 - 0.89 8.3 8.5 2.1 7.1 5.9 1.5 1 0 0 1 1 1 0 Floricaula / Leafy protein DHHW PF14286.1 CAR25931.1 - 1.3 8.2 8.1 2.9 7.0 5.6 1.5 1 0 0 1 1 1 0 DHHW protein CDC45 PF02724.9 CAR25931.1 - 1.6 6.6 11.2 3 5.7 7.8 1.3 1 0 0 1 1 1 0 CDC45-like protein Borrelia_P83 PF05262.6 CAR25931.1 - 3 5.9 13.1 4.6 5.3 9.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Peptidase_S49_N PF08496.5 CAR25931.1 - 3.7 7.3 15.7 9 6.0 10.9 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Peptidase_U57 PF05582.7 CAR25931.1 - 4.9 6.0 8.0 8.8 5.2 5.6 1.3 1 0 0 1 1 1 0 YabG peptidase U57 DUF4557 PF15101.1 CAR25931.1 - 6.9 6.4 19.3 13 5.5 13.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Sec62 PF03839.11 CAR25931.1 - 7.4 5.9 11.6 16 4.8 8.0 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Alg6_Alg8 PF03155.10 CAR25932.1 - 4.1e-153 510.5 42.7 4.8e-153 510.3 29.6 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Vps5 PF09325.5 CAR25933.1 - 1.7e-72 243.5 15.2 1.7e-72 243.5 10.6 1.9 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.19 CAR25933.1 - 6.3e-23 80.7 0.6 6.3e-23 80.7 0.5 2.9 4 0 0 4 4 4 1 PX domain BAR_3_WASP_bdg PF10456.4 CAR25933.1 - 0.0076 15.5 1.3 0.022 14.0 0.9 1.8 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein Hydrolase_6 PF13344.1 CAR25933.1 - 0.52 10.2 3.3 3.7 7.4 0.1 2.9 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase V_ATPase_I PF01496.14 CAR25933.1 - 3.6 5.3 22.9 3.2 5.4 1.0 2.6 2 1 0 2 2 2 0 V-type ATPase 116kDa subunit family Lactamase_B_2 PF12706.2 CAR25934.1 - 1e-37 129.5 0.5 1.6e-37 128.9 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 CAR25934.1 - 4.7e-24 83.6 0.0 9.9e-24 82.5 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease RabGAP-TBC PF00566.13 CAR25935.1 - 2e-50 171.2 2.4 4.9e-50 169.9 1.6 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain THF_DHG_CYH PF00763.18 CAR25936.1 - 9.1e-19 67.6 0.1 3.7e-18 65.6 0.0 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 CAR25936.1 - 1.5e-17 63.1 0.0 2e-10 39.9 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Brix PF04427.13 CAR25937.1 - 3.8e-37 127.8 0.5 5.6e-37 127.2 0.3 1.3 1 0 0 1 1 1 1 Brix domain Nucleoporin_C PF03177.9 CAR25938.1 - 5.1e-69 233.3 21.9 8.2e-69 232.6 15.2 1.3 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 CAR25938.1 - 5.6e-56 190.0 3.0 8.5e-56 189.4 2.1 1.3 1 0 0 1 1 1 1 Nup133 N terminal like DASH_Dad2 PF08654.5 CAR25939.1 - 1.8e-30 104.9 5.0 6.2e-30 103.2 3.5 1.7 1 1 0 1 1 1 1 DASH complex subunit Dad2 DASH_Duo1 PF08651.5 CAR25939.1 - 6.9e-05 22.3 0.7 0.00013 21.4 0.5 1.4 1 0 0 1 1 1 1 DASH complex subunit Duo1 MCPsignal PF00015.16 CAR25939.1 - 0.041 13.4 0.2 0.051 13.1 0.1 1.1 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain FliD_N PF02465.13 CAR25939.1 - 0.07 13.5 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus PilJ PF13675.1 CAR25939.1 - 0.089 13.1 0.3 0.13 12.5 0.2 1.2 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Lipoprotein_20 PF13942.1 CAR25939.1 - 0.095 12.2 0.5 0.19 11.2 0.4 1.5 1 1 0 1 1 1 0 YfhG lipoprotein YlbD_coat PF14071.1 CAR25939.1 - 0.55 10.3 4.8 1.9 8.5 0.5 2.0 2 0 0 2 2 2 0 Putative coat protein MscS_porin PF12795.2 CAR25939.1 - 4.1 6.6 8.2 0.11 11.7 1.7 1.3 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Shugoshin_N PF07558.6 CAR25940.1 - 3.7e-12 45.7 1.1 2.1e-11 43.3 1.2 2.1 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 CAR25940.1 - 8.6e-10 37.9 7.5 1.1e-09 37.5 3.7 2.3 2 0 0 2 2 2 1 Shugoshin C terminus CHZ PF09649.5 CAR25940.1 - 0.0093 15.1 0.3 0.04 13.1 0.2 2.1 1 0 0 1 1 1 1 Histone chaperone domain CHZ IncA PF04156.9 CAR25940.1 - 3.8 7.0 8.6 0.36 10.3 0.8 2.4 2 0 0 2 2 2 0 IncA protein Thymidylat_synt PF00303.14 CAR25941.1 - 1.7e-120 401.0 0.0 1.9e-120 400.9 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Syntaxin-18_N PF10496.4 CAR25942.1 - 1.8e-17 62.9 6.0 1.9e-17 62.8 0.8 2.6 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus Cluap1 PF10234.4 CAR25942.1 - 0.0012 18.1 5.1 0.0012 18.1 3.5 2.4 2 0 0 2 2 2 1 Clusterin-associated protein-1 SNARE PF05739.14 CAR25942.1 - 0.0037 16.9 7.4 0.0037 16.9 5.1 2.1 2 0 0 2 2 2 1 SNARE domain L31 PF09784.4 CAR25942.1 - 0.18 11.8 13.2 0.034 14.2 1.9 3.5 2 2 0 2 2 2 0 Mitochondrial ribosomal protein L31 DUF1217 PF06748.7 CAR25942.1 - 0.34 10.9 4.8 3.9 7.5 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1217) DUF948 PF06103.6 CAR25942.1 - 0.84 9.5 9.6 1.1 9.1 3.6 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Syntaxin PF00804.20 CAR25942.1 - 5.1 7.3 18.0 3.4 7.8 7.8 2.6 2 0 0 2 2 2 0 Syntaxin GTP_EFTU PF00009.22 CAR25943.1 - 2.6e-43 147.6 0.0 4.1e-43 147.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 CAR25943.1 - 8.4e-14 51.4 6.9 2e-13 50.2 4.8 1.7 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.18 CAR25943.1 - 4.7e-06 26.5 0.0 0.00037 20.4 0.0 2.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 CAR25943.1 - 5.9e-05 22.6 0.1 0.00017 21.1 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 CAR25943.1 - 0.00053 20.4 0.0 0.025 15.0 0.0 2.8 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU_D2 PF03144.20 CAR25943.1 - 0.00056 19.9 0.2 0.0018 18.3 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.12 CAR25943.1 - 0.019 15.1 0.2 0.07 13.2 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu C-terminal domain Dabb PF07876.7 CAR25943.1 - 0.24 11.8 2.8 4.3 7.8 0.1 3.2 3 0 0 3 3 3 0 Stress responsive A/B Barrel Domain GP41 PF00517.12 CAR25944.1 - 0.024 14.2 0.7 0.028 13.9 0.5 1.1 1 0 0 1 1 1 0 Retroviral envelope protein MRP-L20 PF12824.2 CAR25945.1 - 9.8e-52 175.2 5.3 1.2e-51 174.9 3.7 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.6 CAR25945.1 - 0.056 13.2 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Neugrin HA2 PF04408.18 CAR25946.1 - 8.1e-24 83.6 0.1 3.2e-23 81.6 0.0 2.2 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CAR25946.1 - 1.7e-21 76.1 0.0 4.2e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CAR25946.1 - 4.6e-15 55.2 0.0 1.3e-14 53.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CAR25946.1 - 1.2e-07 31.9 0.4 4.9e-07 29.9 0.2 2.2 2 0 0 2 2 1 1 AAA domain DEAD PF00270.24 CAR25946.1 - 3.7e-05 23.2 1.7 0.00013 21.5 1.2 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CAR25946.1 - 0.0001 22.2 3.8 0.04 13.7 0.0 3.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CAR25946.1 - 0.0018 18.0 0.1 0.0042 16.7 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain T2SE PF00437.15 CAR25946.1 - 0.0019 17.1 0.0 0.0041 16.0 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.1 CAR25946.1 - 0.0053 16.6 0.7 0.099 12.5 0.5 2.7 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.1 CAR25946.1 - 0.0056 17.0 5.0 0.021 15.1 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 CAR25946.1 - 0.012 15.1 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 CAR25946.1 - 0.023 14.2 0.0 0.048 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRP54 PF00448.17 CAR25946.1 - 0.026 13.9 0.3 0.087 12.2 0.2 1.9 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain PhoH PF02562.11 CAR25946.1 - 0.033 13.3 0.3 0.13 11.4 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.1 CAR25946.1 - 0.035 13.5 0.1 0.19 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CAR25946.1 - 0.035 13.5 0.5 6.6 6.0 0.0 3.6 4 0 0 4 4 4 0 AAA-like domain ABC_tran PF00005.22 CAR25946.1 - 0.038 14.2 1.0 0.16 12.2 0.0 2.5 3 0 0 3 3 3 0 ABC transporter IstB_IS21 PF01695.12 CAR25946.1 - 0.041 13.3 0.6 10 5.4 0.0 3.0 2 1 1 3 3 3 0 IstB-like ATP binding protein Reprolysin PF01421.14 CAR25946.1 - 0.042 13.4 0.1 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 Reprolysin (M12B) family zinc metalloprotease Flavi_DEAD PF07652.9 CAR25946.1 - 0.056 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain Peptidase_M48 PF01435.13 CAR25947.1 - 8.3e-31 107.2 0.0 1.1e-30 106.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Kin17_mid PF10357.4 CAR25948.1 - 1.4e-42 144.3 4.7 2.4e-42 143.5 3.3 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 CAR25948.1 - 4e-07 29.9 3.3 8.2e-07 28.9 2.3 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CAR25948.1 - 1.9e-05 24.6 2.7 3.9e-05 23.6 1.8 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AKAP95 PF04988.7 CAR25948.1 - 0.0031 17.3 3.6 0.0031 17.3 2.5 1.8 2 0 0 2 2 2 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_2 PF12756.2 CAR25948.1 - 0.0031 17.5 0.7 0.0031 17.5 0.5 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) DRIM PF07539.7 CAR25948.1 - 0.01 15.2 1.1 0.019 14.3 0.8 1.4 1 0 0 1 1 1 1 Down-regulated in metastasis TFIID_90kDa PF04494.10 CAR25948.1 - 0.044 13.8 0.3 0.091 12.8 0.2 1.6 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit zf-C2H2 PF00096.21 CAR25948.1 - 0.5 10.8 2.8 1.1 9.7 1.9 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type SNARE_assoc PF09335.6 CAR25949.1 - 2.9e-14 53.3 6.8 2.9e-14 53.3 4.7 2.5 2 1 1 3 3 3 1 SNARE associated Golgi protein Cg6151-P PF10233.4 CAR25949.1 - 0.058 13.3 6.6 0.97 9.4 2.0 3.1 2 1 0 2 2 2 0 Uncharacterized conserved protein CG6151-P DUF4234 PF14018.1 CAR25949.1 - 4.7 7.0 12.2 3.3 7.5 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) DUF3382 PF11862.3 CAR25949.1 - 5.2 7.0 7.7 0.63 9.9 0.7 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3382) DUF3185 PF11381.3 CAR25949.1 - 5.4 6.8 8.3 34 4.3 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3185) adh_short_C2 PF13561.1 CAR25950.1 - 1.5e-29 103.4 0.0 1.9e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CAR25950.1 - 4.1e-23 82.1 0.1 5.6e-23 81.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CAR25950.1 - 1.7e-08 34.3 0.1 5.4e-08 32.6 0.1 1.7 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 CAR25950.1 - 0.035 13.7 0.1 0.054 13.1 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 CAR25950.1 - 0.038 13.4 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pyridox_oxase_2 PF12766.2 CAR25952.1 - 4.4e-30 103.9 0.0 8.9e-30 102.9 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Aminotran_3 PF00202.16 CAR25953.1 - 2.7e-87 292.8 0.0 3.3e-87 292.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III BRCT PF00533.21 CAR25954.1 - 5.3e-09 36.1 0.1 2.2e-08 34.1 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.16 CAR25954.1 - 0.00092 19.2 0.1 0.0029 17.6 0.1 1.9 1 0 0 1 1 1 1 Fibronectin type III domain PTCB-BRCT PF12738.2 CAR25954.1 - 0.008 16.0 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain ATP-synt_F PF01990.12 CAR25955.1 - 4e-29 100.8 0.1 4.6e-29 100.6 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF3089 PF11288.3 CAR25955.1 - 0.11 11.6 0.2 0.23 10.5 0.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3089) Transcrip_reg PF01709.15 CAR25956.1 - 4.8e-71 238.6 0.2 6e-71 238.2 0.2 1.0 1 0 0 1 1 1 1 Transcriptional regulator DUF4258 PF14076.1 CAR25956.1 - 0.00011 22.1 0.0 0.019 14.9 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4258) RRM_1 PF00076.17 CAR25956.1 - 0.062 12.9 0.2 0.33 10.6 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mid2 PF04478.7 CAR25957.1 - 1.3e-55 187.0 0.9 1.3e-55 187.0 0.6 4.2 1 1 1 3 3 3 1 Mid2 like cell wall stress sensor SKG6 PF08693.5 CAR25957.1 - 0.012 14.9 0.6 0.16 11.3 0.4 3.1 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Thg1 PF04446.7 CAR25958.1 - 6.2e-47 158.6 0.9 8.5e-47 158.1 0.6 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.1 CAR25958.1 - 5.5e-39 132.5 0.3 8.9e-39 131.9 0.2 1.3 1 0 0 1 1 1 1 Thg1 C terminal domain Xpo1 PF08389.7 CAR25958.1 - 0.022 14.6 0.5 3.7 7.4 0.1 2.2 2 0 0 2 2 2 0 Exportin 1-like protein SecY PF00344.15 CAR25959.1 - 0.0022 16.9 0.7 0.5 9.2 0.0 2.4 2 0 0 2 2 2 2 SecY translocase TatC PF00902.13 CAR25959.1 - 0.034 13.5 7.7 0.097 12.0 5.3 1.7 1 1 0 1 1 1 0 Sec-independent protein translocase protein (TatC) Ribosomal_S25 PF03297.10 CAR25960.1 - 2.9e-45 152.6 4.8 3.2e-45 152.4 3.3 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Ftsk_gamma PF09397.5 CAR25960.1 - 0.0012 18.5 0.1 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Ftsk gamma domain HTH_CodY PF08222.6 CAR25960.1 - 0.013 14.7 0.1 0.019 14.2 0.1 1.2 1 0 0 1 1 1 0 CodY helix-turn-helix domain GntR PF00392.16 CAR25960.1 - 0.059 12.8 0.1 0.091 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family Ran_BP1 PF00638.13 CAR25961.1 - 1.5e-34 118.6 0.3 4e-34 117.2 0.2 1.8 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.6 CAR25961.1 - 1.3e-09 38.3 3.1 1.3e-09 38.3 2.1 4.4 3 1 0 3 3 3 1 NUP50 (Nucleoporin 50 kDa) Nucleoporin_FG PF13634.1 CAR25961.1 - 0.014 15.6 25.5 0.014 15.6 17.7 5.2 3 1 2 5 5 5 0 Nucleoporin FG repeat region MA3 PF02847.12 CAR25962.1 - 5.7e-27 93.6 0.2 5.7e-27 93.6 0.2 2.3 3 0 0 3 3 3 1 MA3 domain MIF4G PF02854.14 CAR25962.1 - 3.1e-22 79.0 3.6 3.1e-22 79.0 2.5 2.0 2 0 0 2 2 2 1 MIF4G domain AAA PF00004.24 CAR25963.1 - 1.2e-35 122.5 0.0 2.4e-35 121.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CAR25963.1 - 2.3e-07 31.0 0.1 9.1e-05 22.5 0.0 2.7 2 1 1 3 3 2 1 AAA ATPase domain AAA_14 PF13173.1 CAR25963.1 - 7.9e-07 29.0 0.0 2.8e-06 27.2 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CAR25963.1 - 3.6e-06 27.8 0.0 1.1e-05 26.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CAR25963.1 - 7.2e-06 26.1 0.1 0.0012 19.0 0.0 2.9 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.7 CAR25963.1 - 1e-05 24.6 0.0 3.5e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 CAR25963.1 - 1.9e-05 24.3 0.0 0.00013 21.7 0.0 2.5 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CAR25963.1 - 2.9e-05 24.0 0.0 0.00014 21.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 CAR25963.1 - 4.5e-05 23.3 0.0 0.00017 21.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CAR25963.1 - 0.00013 21.3 0.0 0.00029 20.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 CAR25963.1 - 0.00015 21.8 0.0 0.00029 20.9 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Zeta_toxin PF06414.7 CAR25963.1 - 0.00015 20.9 0.0 0.00023 20.3 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 CAR25963.1 - 0.00044 20.5 0.2 0.0015 18.8 0.0 2.1 2 1 0 2 2 1 1 AAA domain NACHT PF05729.7 CAR25963.1 - 0.00075 19.1 0.1 0.0034 17.0 0.0 2.0 2 0 0 2 2 2 1 NACHT domain Mg_chelatase PF01078.16 CAR25963.1 - 0.0011 18.2 0.1 0.0024 17.0 0.0 1.6 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 CAR25963.1 - 0.0011 18.7 0.2 0.0064 16.2 0.1 2.2 2 1 0 2 2 2 1 Part of AAA domain RNA_helicase PF00910.17 CAR25963.1 - 0.0017 18.5 0.0 0.0041 17.2 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_11 PF13086.1 CAR25963.1 - 0.0018 17.8 0.0 0.0077 15.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CAR25963.1 - 0.0036 16.7 1.1 0.096 12.0 0.1 2.6 1 1 2 3 3 2 1 AAA domain AAA_28 PF13521.1 CAR25963.1 - 0.005 16.8 0.0 0.0086 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 CAR25963.1 - 0.0056 16.1 0.0 0.028 13.8 0.0 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF815 PF05673.8 CAR25963.1 - 0.006 15.5 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Viral_helicase1 PF01443.13 CAR25963.1 - 0.0079 15.7 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.6 CAR25963.1 - 0.0083 15.7 0.0 0.047 13.2 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 CAR25963.1 - 0.0097 16.2 0.0 0.023 15.0 0.0 1.8 2 1 0 2 2 1 1 ABC transporter TIP49 PF06068.8 CAR25963.1 - 0.0099 14.6 0.0 0.016 13.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Bac_DnaA PF00308.13 CAR25963.1 - 0.017 14.7 0.0 0.037 13.6 0.0 1.5 1 1 0 1 1 1 0 Bacterial dnaA protein Oxidored_nitro PF00148.14 CAR25963.1 - 0.025 13.2 0.0 2.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase Rad17 PF03215.10 CAR25963.1 - 0.045 12.4 0.0 0.07 11.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein NB-ARC PF00931.17 CAR25963.1 - 0.062 12.1 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain UPF0079 PF02367.12 CAR25963.1 - 0.071 12.7 0.1 0.19 11.3 0.0 1.7 2 0 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 CPT PF07931.7 CAR25963.1 - 0.084 12.4 0.0 0.15 11.6 0.0 1.5 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_24 PF13479.1 CAR25963.1 - 0.11 12.0 0.0 0.36 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain tRNA_lig_kinase PF08303.6 CAR25963.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 tRNA ligase kinase domain Parvo_NS1 PF01057.12 CAR25963.1 - 0.14 11.0 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Evr1_Alr PF04777.8 CAR25964.1 - 7.4e-29 99.5 3.1 7.4e-29 99.5 2.2 1.6 2 0 0 2 2 2 1 Erv1 / Alr family WH2 PF02205.15 CAR25965.1 - 2.6e-13 49.0 1.8 2.2e-09 36.6 0.0 3.2 3 0 0 3 3 3 2 WH2 motif DUF3445 PF11927.3 CAR25966.1 - 2.2e-60 204.1 0.0 3.4e-60 203.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Alba PF01918.16 CAR25967.1 - 0.0025 17.3 0.2 0.013 15.0 0.1 2.0 1 1 0 1 1 1 1 Alba Ribosomal_L10 PF00466.15 CAR25968.1 - 2.1e-27 94.9 0.1 3.5e-27 94.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 CAR25968.1 - 3.2e-18 65.9 4.8 2.5e-17 63.0 1.3 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein Abhydrolase_6 PF12697.2 CAR25970.1 - 1.4e-30 106.9 0.0 1.7e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAR25970.1 - 3.4e-16 59.4 0.0 6.8e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CAR25970.1 - 1.3e-11 44.4 0.0 1.6e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 CAR25970.1 - 1.3e-09 37.9 0.0 1.9e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_2 PF02230.11 CAR25970.1 - 0.002 17.5 0.0 0.06 12.7 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DUF676 PF05057.9 CAR25970.1 - 0.013 14.8 0.0 0.046 13.0 0.0 1.8 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Esterase PF00756.15 CAR25970.1 - 0.015 14.7 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.20 CAR25970.1 - 0.025 14.1 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2305 PF10230.4 CAR25970.1 - 0.033 13.6 0.0 0.066 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_3 PF07859.8 CAR25970.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Glucan_synthase PF02364.10 CAR25971.1 - 0 1457.9 0.0 0 1457.4 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 CAR25971.1 - 2.6e-39 133.7 0.0 6e-39 132.5 0.0 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glyco_hydro_72 PF03198.9 CAR25972.1 - 1.2e-137 458.1 2.4 1.5e-137 457.7 1.6 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 CAR25972.1 - 8.6e-16 58.2 0.1 2.4e-15 56.7 0.1 1.8 1 0 0 1 1 1 1 X8 domain TIM21 PF08294.6 CAR25973.1 - 1.4e-51 174.0 0.0 1.7e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 TIM21 DUF443 PF04276.7 CAR25973.1 - 0.16 11.3 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF443) KOW PF00467.24 CAR25974.1 - 6.1e-05 22.5 2.1 8.6e-05 22.0 0.6 1.9 2 1 0 2 2 2 1 KOW motif 6PF2K PF01591.13 CAR25975.1 - 8.1e-63 211.4 1.2 1.1e-62 210.9 0.9 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CAR25975.1 - 5.4e-20 72.0 0.2 9.4e-19 68.0 0.1 2.5 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 CAR25975.1 - 0.0011 18.9 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain PAP2 PF01569.16 CAR25976.1 - 1.9e-19 69.6 0.5 3.2e-19 68.8 0.3 1.3 1 0 0 1 1 1 1 PAP2 superfamily HEAT PF02985.17 CAR25977.1 - 2.4e-15 55.1 17.8 0.0013 18.6 0.0 10.4 11 0 0 11 11 11 3 HEAT repeat HEAT_EZ PF13513.1 CAR25977.1 - 4.3e-14 52.5 9.1 1.9e-05 25.0 0.0 8.7 8 2 2 10 10 10 3 HEAT-like repeat HEAT_2 PF13646.1 CAR25977.1 - 3.2e-12 46.5 5.4 3.5e-05 24.0 0.0 6.8 4 3 3 7 7 7 3 HEAT repeats IBN_N PF03810.14 CAR25977.1 - 2.5e-10 40.1 1.7 1.1e-08 34.8 0.8 3.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain CLASP_N PF12348.3 CAR25977.1 - 0.00017 21.0 2.1 0.64 9.3 0.0 4.5 5 1 2 7 7 7 3 CLASP N terminal Arm PF00514.18 CAR25977.1 - 0.0014 18.4 3.7 4.9 7.1 0.0 5.7 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat RICTOR_V PF14668.1 CAR25977.1 - 0.0062 16.4 0.8 0.2 11.5 0.1 3.4 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 DUF3385 PF11865.3 CAR25977.1 - 0.013 15.4 0.3 2.2 8.1 0.1 3.9 1 1 3 4 4 4 0 Domain of unknown function (DUF3385) ACBP PF00887.14 CAR25978.1 - 5.2e-29 99.7 3.4 5.7e-29 99.6 2.3 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein FERM_M PF00373.13 CAR25978.1 - 0.045 13.9 0.3 4.7 7.3 0.0 2.0 1 1 1 2 2 2 0 FERM central domain DUF1413 PF07205.6 CAR25978.1 - 0.054 13.0 0.9 0.096 12.2 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1413) ORMDL PF04061.9 CAR25979.1 - 2.5e-58 195.4 5.7 3e-58 195.2 3.9 1.1 1 0 0 1 1 1 1 ORMDL family CN_hydrolase PF00795.17 CAR25980.1 - 5e-31 107.5 0.0 6.2e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DAO PF01266.19 CAR25981.1 - 8.8e-24 84.0 0.0 1e-23 83.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CAR25981.1 - 0.016 15.2 1.9 0.03 14.3 0.2 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pkinase PF00069.20 CAR25982.1 - 5.8e-72 241.9 0.0 7.1e-72 241.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR25982.1 - 9e-33 113.4 0.0 1.2e-32 112.9 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR25982.1 - 4.1e-06 25.9 0.0 6.8e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CAR25982.1 - 0.0076 15.3 0.1 0.018 14.1 0.0 1.6 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CAR25982.1 - 0.026 14.2 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 CAR25982.1 - 0.038 13.3 0.1 0.06 12.6 0.1 1.3 1 0 0 1 1 1 0 RIO1 family LRR_4 PF12799.2 CAR25983.1 - 7.6e-05 22.2 22.5 0.0033 16.9 1.5 5.5 5 1 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAR25983.1 - 0.00045 19.9 11.3 0.011 15.5 1.1 4.6 3 1 0 3 3 3 2 Leucine rich repeat UNC119_bdg PF15435.1 CAR25983.1 - 0.026 13.8 0.1 0.081 12.2 0.0 1.8 2 0 0 2 2 2 0 UNC119-binding protein C5orf30 homologue LRR_1 PF00560.28 CAR25983.1 - 0.12 12.4 13.9 4.6 7.6 0.3 6.6 6 1 1 7 7 7 0 Leucine Rich Repeat LRR_7 PF13504.1 CAR25983.1 - 0.7 10.3 11.7 99 3.8 0.0 6.7 6 0 0 6 6 6 0 Leucine rich repeat Pex14_N PF04695.8 CAR25984.1 - 0.27 11.2 0.0 0.27 11.2 0.0 3.8 3 2 2 5 5 5 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2439 PF10382.4 CAR25985.1 - 5.5e-11 42.5 0.1 7.8e-11 42.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Transaldolase PF00923.14 CAR25986.1 - 3.2e-95 318.5 0.1 3.7e-95 318.3 0.1 1.0 1 0 0 1 1 1 1 Transaldolase DUF740 PF05340.7 CAR25986.1 - 0.11 10.8 0.0 0.16 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF740) zf-C2H2_4 PF13894.1 CAR25987.1 - 3.9e-07 29.9 16.0 0.02 15.1 1.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 CAR25987.1 - 1.4e-05 25.1 15.8 0.0056 16.9 0.9 3.7 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 CAR25987.1 - 0.035 14.1 5.2 0.83 9.8 0.1 2.5 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF629 PF04780.7 CAR25987.1 - 0.13 10.7 1.7 2.4 6.6 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF629) WRKY PF03106.10 CAR25987.1 - 0.5 10.2 4.3 0.27 11.0 0.3 2.4 3 0 0 3 3 3 0 WRKY DNA -binding domain zf-H2C2_2 PF13465.1 CAR25987.1 - 1.2 9.5 21.3 1.8 8.9 0.6 4.6 4 1 0 4 4 4 0 Zinc-finger double domain PyrI_C PF02748.10 CAR25987.1 - 1.9 7.9 5.5 2.5 7.6 0.1 3.0 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_jaz PF12171.3 CAR25987.1 - 4.9 7.4 12.9 3.3 7.9 0.4 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding AhpC-TSA PF00578.16 CAR25988.1 - 4.2e-29 100.7 0.0 5.3e-29 100.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CAR25988.1 - 3e-10 39.8 0.0 3.8e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CAR25988.1 - 1.8e-07 30.7 0.1 2.9e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin DUF2464 PF10240.4 CAR25988.1 - 0.085 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2464) WD40 PF00400.27 CAR25989.1 - 3.8e-55 181.9 19.0 5.3e-12 45.1 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 CAR25989.1 - 5.9e-48 162.5 3.0 1.1e-47 161.6 2.1 1.5 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit LisH PF08513.6 CAR25989.1 - 1.2e-06 28.0 0.1 3.1e-06 26.7 0.1 1.8 1 0 0 1 1 1 1 LisH Nup160 PF11715.3 CAR25989.1 - 2.4e-06 26.0 3.0 0.067 11.3 0.1 3.7 2 2 1 4 4 4 2 Nucleoporin Nup120/160 Neur_chan_memb PF02932.11 CAR25989.1 - 9.3 6.0 13.3 8.9 6.1 0.7 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region GPI2 PF06432.6 CAR25990.1 - 5.7e-51 173.5 25.6 7.8e-51 173.0 17.7 1.2 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase PGI PF00342.14 CAR25992.1 - 3.5e-222 738.0 4.3 4.4e-222 737.7 3.0 1.1 1 0 0 1 1 1 1 Phosphoglucose isomerase WD40 PF00400.27 CAR25993.1 - 4.7e-24 83.3 5.6 1.7e-06 27.7 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CAR25993.1 - 2.8e-17 62.3 0.7 6.1e-17 61.2 0.5 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 CAR25993.1 - 7e-05 22.6 0.0 0.021 14.5 0.0 3.0 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 CAR25993.1 - 0.00038 19.8 0.0 3.4 7.2 0.0 3.8 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain SdiA-regulated PF06977.6 CAR25993.1 - 0.033 13.1 0.0 3 6.7 0.0 2.4 2 0 0 2 2 2 0 SdiA-regulated Mt_ATP-synt_B PF05405.9 CAR25994.1 - 7.8e-56 188.0 9.9 9.4e-56 187.7 6.9 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) SLS PF14611.1 CAR25994.1 - 0.011 15.1 2.6 0.017 14.5 1.8 1.2 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator SRX PF09201.5 CAR25994.1 - 0.024 14.2 1.6 0.035 13.7 1.1 1.2 1 0 0 1 1 1 0 SRX Orthopox_A5L PF06193.6 CAR25994.1 - 0.076 12.9 3.0 0.077 12.9 1.5 1.6 1 1 0 1 1 1 0 Orthopoxvirus A5L protein-like Gastrin PF00918.12 CAR25994.1 - 0.56 11.0 3.0 1.2 9.9 1.4 1.9 2 0 0 2 2 2 0 Gastrin/cholecystokinin family NpwBP PF12622.2 CAR25995.1 - 2.1e-14 53.7 0.9 3.9e-14 52.8 0.1 1.8 2 0 0 2 2 2 1 mRNA biogenesis factor Med8 PF10232.4 CAR25996.1 - 6.6e-43 146.8 2.0 8e-43 146.5 1.4 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Mito_carr PF00153.22 CAR25997.1 - 3.4e-80 263.8 3.5 1.1e-28 98.7 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 CAR25997.1 - 0.0067 16.4 0.5 2.1 8.4 0.0 2.5 2 0 0 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family HMD PF03201.11 CAR25997.1 - 0.032 14.1 0.0 13 5.8 0.0 2.9 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase DUF750 PF04721.12 CAR25997.1 - 0.038 13.9 1.3 1 9.4 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF750) DUF2574 PF10836.3 CAR25997.1 - 0.13 12.0 0.1 0.41 10.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2574) Ribosomal_L21e PF01157.13 CAR25998.1 - 6.5e-37 125.3 3.4 1e-36 124.6 2.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e DUF1989 PF09347.5 CAR25998.1 - 0.0017 17.8 0.0 0.0022 17.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Ribosomal_S4 PF00163.14 CAR25999.1 - 6.9e-25 87.2 2.3 1.1e-24 86.6 1.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CAR25999.1 - 1.4e-11 43.6 0.5 1.4e-11 43.6 0.3 2.2 2 0 0 2 2 2 1 S4 domain HMGL-like PF00682.14 CAR26000.1 - 1.6e-73 247.3 0.1 2.1e-73 246.8 0.1 1.2 1 0 0 1 1 1 1 HMGL-like GcpE PF04551.9 CAR26000.1 - 0.0089 14.8 0.1 0.014 14.1 0.1 1.4 1 1 0 1 1 1 1 GcpE protein Trp_syntA PF00290.15 CAR26000.1 - 0.043 12.3 0.0 1.9 6.9 0.0 2.4 2 0 0 2 2 2 0 Tryptophan synthase alpha chain DUF3535 PF12054.3 CAR26001.1 - 2.5e-138 461.4 0.0 8.4e-138 459.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 CAR26001.1 - 2.3e-78 263.0 0.0 3.8e-78 262.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CAR26001.1 - 7e-14 51.4 0.0 2.9e-13 49.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HEAT PF02985.17 CAR26001.1 - 6e-09 35.2 8.8 0.82 9.9 0.0 9.0 9 0 0 9 9 9 3 HEAT repeat Vac14_Fab1_bd PF12755.2 CAR26001.1 - 7.6e-05 23.0 0.1 1.7 9.0 0.0 4.7 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CAR26001.1 - 8.9e-05 22.8 4.4 32 5.1 0.0 7.3 7 0 0 7 7 7 0 HEAT-like repeat cwf18 PF08315.7 CAR26002.1 - 2.1e-05 24.9 10.9 0.0026 18.2 0.6 2.3 1 1 1 2 2 2 2 cwf18 pre-mRNA splicing factor UPF0016 PF01169.14 CAR26003.1 - 2.2e-40 136.6 21.9 1.3e-20 73.3 4.1 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Cation_ATPase_C PF00689.16 CAR26003.1 - 3 7.3 11.5 16 4.9 7.9 2.0 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus AAA PF00004.24 CAR26004.1 - 7.4e-33 113.5 0.0 1.4e-32 112.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CAR26004.1 - 1.1e-06 29.4 0.0 3.1e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CAR26004.1 - 1.4e-06 27.9 0.0 3.6e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 CAR26004.1 - 7.1e-06 26.1 0.0 2.4e-05 24.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CAR26004.1 - 7.8e-06 26.2 0.0 2.3e-05 24.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CAR26004.1 - 4.5e-05 23.2 0.1 0.072 12.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 CAR26004.1 - 0.00036 20.1 0.0 0.00066 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CAR26004.1 - 0.00052 20.0 0.0 0.0022 18.0 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 CAR26004.1 - 0.00092 18.9 0.4 0.0028 17.3 0.1 1.8 2 1 0 2 2 1 1 Archaeal ATPase AAA_14 PF13173.1 CAR26004.1 - 0.0012 18.7 0.1 0.0036 17.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CAR26004.1 - 0.0024 17.7 0.0 0.0053 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 CAR26004.1 - 0.0025 17.4 0.0 0.0047 16.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 CAR26004.1 - 0.0028 17.8 0.0 0.0092 16.1 0.0 2.0 1 0 0 1 1 1 1 RNA helicase T2SE PF00437.15 CAR26004.1 - 0.0036 16.2 0.0 0.0071 15.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_25 PF13481.1 CAR26004.1 - 0.0047 16.3 0.0 0.027 13.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 CAR26004.1 - 0.005 16.4 0.0 0.0093 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 CAR26004.1 - 0.0052 15.7 0.0 0.0098 14.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Rad17 PF03215.10 CAR26004.1 - 0.0054 15.4 0.0 0.013 14.1 0.0 1.6 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_23 PF13476.1 CAR26004.1 - 0.0054 17.0 1.7 0.0098 16.2 0.1 2.1 1 1 1 2 2 2 1 AAA domain NACHT PF05729.7 CAR26004.1 - 0.011 15.4 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain PIF1 PF05970.9 CAR26004.1 - 0.011 14.7 0.1 1.5 7.6 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase AAA_30 PF13604.1 CAR26004.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 CAR26004.1 - 0.016 14.0 0.0 0.038 12.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain RuvB_N PF05496.7 CAR26004.1 - 0.019 13.9 0.0 0.051 12.6 0.0 1.6 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus ABC_tran PF00005.22 CAR26004.1 - 0.022 15.0 0.0 0.06 13.6 0.0 1.8 2 0 0 2 2 1 0 ABC transporter NTPase_1 PF03266.10 CAR26004.1 - 0.025 14.3 0.1 0.05 13.3 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_3 PF07726.6 CAR26004.1 - 0.028 14.0 0.0 0.79 9.3 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 CAR26004.1 - 0.041 13.6 0.2 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 CAR26004.1 - 0.044 13.2 0.0 0.12 11.7 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 CAR26004.1 - 0.065 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 CAR26004.1 - 0.071 12.3 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein KaiC PF06745.8 CAR26004.1 - 0.091 11.8 0.1 0.44 9.6 0.0 1.9 1 1 1 2 2 2 0 KaiC KTI12 PF08433.5 CAR26004.1 - 0.1 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_28 PF13521.1 CAR26004.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain tRNA_int_end_N2 PF12928.2 CAR26005.1 - 1.9e-20 72.0 0.0 3.6e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term BRO1 PF03097.13 CAR26006.1 - 7.3e-94 314.5 8.7 7.3e-94 314.5 6.1 2.3 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 CAR26006.1 - 5.5e-50 170.0 8.5 5.5e-50 170.0 5.9 1.6 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV MBA1 PF07961.6 CAR26007.1 - 1.1e-101 338.5 1.2 1.4e-101 338.2 0.8 1.0 1 0 0 1 1 1 1 MBA1-like protein Glyco_transf_20 PF00982.16 CAR26007.1 - 0.015 13.8 0.0 0.019 13.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 20 Sec16_C PF12931.2 CAR26008.1 - 5.5e-80 269.1 0.0 9.2e-80 268.4 0.0 1.4 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 CAR26008.1 - 3.5e-18 65.6 0.1 1.2e-17 63.9 0.1 2.1 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Radical_SAM PF04055.16 CAR26009.1 - 2.9e-16 60.0 0.5 6.6e-16 58.9 0.1 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 CAR26009.1 - 4.6e-12 45.8 0.0 1.4e-11 44.2 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Ceramidase PF05875.7 CAR26010.1 - 8e-95 316.9 17.1 9.3e-95 316.7 11.9 1.0 1 0 0 1 1 1 1 Ceramidase VIT1 PF01988.14 CAR26010.1 - 0.0093 15.4 0.9 0.013 15.0 0.1 1.6 2 0 0 2 2 2 1 VIT family SRF-TF PF00319.13 CAR26011.1 - 1.8e-23 81.5 0.0 3.1e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF605 PF04652.11 CAR26011.1 - 0.43 9.9 28.2 0.76 9.1 19.6 1.4 1 0 0 1 1 1 0 Vta1 like HSP20 PF00011.16 CAR26012.1 - 8.5e-18 64.0 0.0 1.1e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family FAD_binding_7 PF03441.9 CAR26013.1 - 1.2e-80 270.7 0.2 4.6e-80 268.7 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 CAR26013.1 - 6.5e-27 94.2 0.5 2.4e-26 92.4 0.3 1.9 1 1 0 1 1 1 1 DNA photolyase SnoaL_4 PF13577.1 CAR26014.1 - 1.6e-22 79.7 0.0 1.9e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain Lumazine_bd_2 PF12893.2 CAR26014.1 - 0.069 13.6 0.0 0.16 12.4 0.0 1.8 1 1 0 1 1 1 0 Putative lumazine-binding Epimerase PF01370.16 CAR26015.1 - 7.4e-24 84.4 0.0 1.2e-23 83.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CAR26015.1 - 3.9e-17 61.8 0.0 6.8e-17 61.0 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CAR26015.1 - 1.4e-11 43.8 0.0 3.8e-10 39.1 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 CAR26015.1 - 1.7e-09 37.9 0.0 3.9e-09 36.7 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 CAR26015.1 - 2.2e-07 30.0 0.1 3.6e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 CAR26015.1 - 1.6e-05 24.8 0.0 4.3e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 CAR26015.1 - 0.00014 21.2 0.0 0.042 13.0 0.0 2.7 3 0 0 3 3 3 1 NmrA-like family KR PF08659.5 CAR26015.1 - 0.00056 19.6 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 CAR26015.1 - 0.0051 15.8 0.0 0.007 15.3 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase RmlD_sub_bind PF04321.12 CAR26015.1 - 0.0061 15.4 0.0 0.0092 14.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain DUF2362 PF10154.4 CAR26015.1 - 0.01 14.5 0.1 0.015 14.0 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) DUF2788 PF10981.3 CAR26015.1 - 0.072 12.8 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2788) Zn_clus PF00172.13 CAR26016.1 - 4.9e-08 32.7 10.9 1.1e-07 31.5 7.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.5 CAR26016.1 - 2 8.5 8.4 0.77 9.9 0.9 2.6 2 0 0 2 2 2 0 Opy2 protein MFS_1 PF07690.11 CAR26017.1 - 4.2e-32 111.2 29.1 4.2e-32 111.2 20.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 CAR26017.1 - 4.7e-05 21.7 2.4 6.9e-05 21.2 1.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GST_N PF02798.15 CAR26018.1 - 4.5e-13 49.1 0.0 2.6e-12 46.7 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CAR26018.1 - 4.4e-08 33.0 0.0 9.4e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CAR26018.1 - 1.2e-07 31.8 0.0 1.3e-06 28.4 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CAR26018.1 - 3.4e-07 30.6 0.0 6.4e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 CAR26018.1 - 5.8e-07 29.4 0.0 1.3e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CAR26018.1 - 0.0053 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Flo11 PF10182.4 CAR26019.1 - 2.5e-47 160.2 1.7 4.4e-47 159.4 1.2 1.4 1 0 0 1 1 1 1 Flo11 domain MFS_1 PF07690.11 CAR26020.1 - 6.1e-34 117.2 26.3 7.6e-34 116.9 18.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Trypan_PARP PF05887.6 CAR26021.1 - 0.16 11.7 3.2 0.2 11.4 2.2 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF1510 PF07423.6 CAR26021.1 - 0.45 9.8 7.5 0.48 9.7 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2890 PF11081.3 CAR26021.1 - 4.9 7.1 8.3 5.7 6.9 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) CDC45 PF02724.9 CAR26021.1 - 7.1 4.5 8.7 7 4.5 6.0 1.0 1 0 0 1 1 1 0 CDC45-like protein DUP PF00674.13 CAR26022.1 - 7.7e-15 54.7 0.5 1.7e-14 53.6 0.3 1.7 1 1 0 1 1 1 1 DUP family DUP PF00674.13 CAR26024.1 - 3.4e-05 23.7 1.7 3.4e-05 23.7 1.2 2.3 2 0 0 2 2 2 1 DUP family DUF4532 PF15046.1 CAR26024.1 - 0.12 11.3 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4532) PepSY_TM_3 PF13706.1 CAR26025.1 - 0.11 11.8 1.1 0.28 10.6 0.7 1.6 1 0 0 1 1 1 0 PepSY-associated TM helix DUP PF00674.13 CAR26026.1 - 1.1e-06 28.5 0.2 1.1e-06 28.5 0.1 2.9 2 1 1 3 3 3 1 DUP family DUP PF00674.13 CAR26027.1 - 2.4e-25 88.5 4.9 2e-15 56.6 0.1 2.6 2 1 0 2 2 2 2 DUP family DUF1360 PF07098.6 CAR26027.1 - 0.027 14.2 1.2 0.069 12.8 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) NDUF_C2 PF06374.6 CAR26027.1 - 0.035 14.1 0.1 0.1 12.5 0.1 1.8 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) AAA_26 PF13500.1 CAR26028.1 - 3.5e-41 141.0 0.0 4.2e-41 140.7 0.0 1.0 1 0 0 1 1 1 1 AAA domain Aminotran_3 PF00202.16 CAR26029.1 - 1.2e-84 284.0 0.0 3.8e-84 282.4 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 CAR26029.1 - 9.6e-05 21.6 0.0 0.00017 20.8 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase DUP PF00674.13 CAR26030.1 - 9.9e-08 31.9 0.2 9.9e-08 31.9 0.1 2.4 2 0 0 2 2 2 1 DUP family BCD PF15461.1 CAR26031.1 - 0.038 13.4 0.0 0.051 12.9 0.0 1.1 1 0 0 1 1 1 0 Beta-carotene 15,15'-dioxygenase DUP PF00674.13 CAR26032.1 - 3.1e-27 94.6 6.3 6.8e-16 58.1 0.1 2.4 2 0 0 2 2 2 2 DUP family BEN PF10523.4 CAR26032.1 - 0.084 12.9 0.1 13 5.9 0.0 2.5 2 0 0 2 2 2 0 BEN domain BNR PF02012.15 CAR26033.1 - 2.7e-10 38.5 12.8 0.62 10.1 0.2 7.3 6 0 0 6 6 6 3 BNR/Asp-box repeat Mo-co_dimer PF03404.11 CAR26033.1 - 8.9e-05 22.1 0.3 11 5.6 0.0 4.4 5 0 0 5 5 5 3 Mo-co oxidoreductase dimerisation domain PSII_BNR PF14870.1 CAR26033.1 - 0.00094 18.2 0.2 0.074 12.0 0.0 3.3 4 0 0 4 4 4 1 Photosynthesis system II assembly factor YCF48 ApoC-I PF04691.7 CAR26033.1 - 0.011 15.4 0.0 0.033 13.8 0.0 1.8 1 0 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) Nitr_red_alph_N PF14710.1 CAR26033.1 - 0.83 9.9 4.8 0.63 10.3 0.1 3.3 3 0 0 3 3 3 0 Respiratory nitrate reductase alpha N-terminal adh_short_C2 PF13561.1 CAR26034.1 - 1.6e-18 67.4 0.0 1.8e-18 67.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CAR26034.1 - 9e-18 64.7 0.0 1.1e-17 64.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CAR26034.1 - 5.9e-11 42.3 0.0 1.1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Aldolase_II PF00596.16 CAR26035.1 - 7.6e-48 162.5 0.1 1.1e-47 162.0 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Fungal_trans_2 PF11951.3 CAR26036.1 - 3.7e-09 35.6 0.1 2.2e-08 33.1 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR26036.1 - 4.8e-07 29.5 11.0 1.3e-06 28.1 7.6 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RimK PF08443.6 CAR26036.1 - 0.029 13.8 0.0 0.1 12.0 0.0 1.8 2 0 0 2 2 2 0 RimK-like ATP-grasp domain MFS_1 PF07690.11 CAR26037.1 - 7.4e-31 107.1 25.6 7.9e-31 107.0 17.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Peptidase_M20 PF01546.23 CAR26038.1 - 0.075 12.5 0.0 0.084 12.3 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Peptidase_M20 PF01546.23 CAR26039.1 - 3.1e-24 85.5 0.0 4.4e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CAR26039.1 - 1.6e-05 24.6 0.0 3.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 CAR26039.1 - 7.8e-05 22.4 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Epimerase PF01370.16 CAR26040.1 - 7.5e-23 81.1 0.0 1.8e-22 79.9 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CAR26040.1 - 7.9e-14 51.0 0.0 1.2e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CAR26040.1 - 2e-12 46.6 0.0 1.8e-11 43.4 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 CAR26040.1 - 3.8e-12 46.5 0.0 1.2e-11 44.9 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 CAR26040.1 - 4.7e-06 26.6 0.0 2.9e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 CAR26040.1 - 7e-06 25.1 0.0 5.2e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.8 CAR26040.1 - 0.0001 21.6 0.2 0.00054 19.2 0.2 2.2 2 1 0 2 2 2 1 NmrA-like family KR PF08659.5 CAR26040.1 - 0.00062 19.4 0.0 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 CAR26040.1 - 0.014 14.3 0.0 0.34 9.7 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain Mito_carr PF00153.22 CAR26041.1 - 3.2e-60 199.8 1.4 5.5e-20 70.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DHODB_Fe-S_bind PF10418.4 CAR26041.1 - 0.052 13.0 1.2 0.12 11.8 0.1 2.1 2 0 0 2 2 2 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Mito_carr PF00153.22 CAR26042.1 - 2e-46 155.6 6.9 1.3e-19 69.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Polysacc_deac_1 PF01522.16 CAR26043.1 - 3.6e-27 94.4 0.0 5.3e-27 93.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 CAR26043.1 - 9.2e-06 24.7 0.0 1.1e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 GRIP PF01465.15 CAR26044.1 - 4.5e-15 54.8 0.2 1.5e-14 53.2 0.1 2.0 1 0 0 1 1 1 1 GRIP domain Spc7 PF08317.6 CAR26044.1 - 1.7e-05 23.6 140.1 5e-05 22.1 10.3 6.2 2 2 4 6 6 6 5 Spc7 kinetochore protein Reo_sigmaC PF04582.7 CAR26044.1 - 6.3e-05 22.3 62.5 0.065 12.3 5.9 6.6 2 2 3 6 6 6 5 Reovirus sigma C capsid protein Fib_alpha PF08702.5 CAR26044.1 - 0.00062 19.9 16.4 0.00062 19.9 11.4 7.8 2 2 5 7 7 7 2 Fibrinogen alpha/beta chain family IncA PF04156.9 CAR26044.1 - 0.0032 17.0 144.1 0.1 12.1 21.6 7.7 2 2 5 7 7 7 3 IncA protein ATG16 PF08614.6 CAR26044.1 - 0.0045 16.8 142.4 0.45 10.2 10.2 7.8 1 1 6 7 7 7 4 Autophagy protein 16 (ATG16) SlyX PF04102.7 CAR26044.1 - 0.0066 16.7 6.7 0.0066 16.7 4.7 10.9 5 3 4 10 10 10 2 SlyX AAA_13 PF13166.1 CAR26044.1 - 0.03 12.8 132.7 0.011 14.2 14.1 4.7 1 1 0 3 3 3 0 AAA domain DUF948 PF06103.6 CAR26044.1 - 0.066 13.0 0.2 0.066 13.0 0.2 10.2 5 5 6 11 11 11 0 Bacterial protein of unknown function (DUF948) Filament PF00038.16 CAR26044.1 - 0.57 9.5 124.2 0.074 12.5 7.9 6.5 2 2 1 4 4 4 0 Intermediate filament protein EzrA PF06160.7 CAR26044.1 - 0.89 7.6 117.4 0.042 12.0 10.5 5.1 3 1 1 5 5 5 0 Septation ring formation regulator, EzrA Bacillus_HBL PF05791.6 CAR26044.1 - 1.1 8.6 93.6 0.35 10.1 3.2 8.1 3 3 3 7 7 7 0 Bacillus haemolytic enterotoxin (HBL) Myosin_tail_1 PF01576.14 CAR26044.1 - 1.2 6.7 149.3 0.042 11.5 39.8 3.9 1 1 2 3 3 3 0 Myosin tail AAA_27 PF13514.1 CAR26044.1 - 1.5 6.3 96.7 0.27 8.8 12.3 5.0 1 1 2 4 4 4 0 AAA domain RasGEF PF00617.14 CAR26045.1 - 3e-56 190.1 0.5 1.7e-55 187.6 0.0 2.3 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 CAR26045.1 - 6.6e-19 67.9 0.0 3.6e-18 65.5 0.0 2.3 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 CAR26045.1 - 1.1e-09 37.6 0.1 2.3e-09 36.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CAR26045.1 - 2.5e-07 29.9 0.0 5.5e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CAR26045.1 - 3.5e-07 29.5 0.0 8.3e-07 28.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain TFIIB PF00382.14 CAR26046.1 - 2.2e-40 136.2 1.9 2.6e-26 91.2 0.8 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 CAR26046.1 - 9.1e-14 50.5 0.5 1.7e-13 49.5 0.4 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding tRNA-synt_2 PF00152.15 CAR26047.1 - 2e-83 279.9 0.3 3.4e-83 279.1 0.2 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CAR26047.1 - 2.7e-07 30.3 0.0 5.9e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CAR26047.1 - 0.011 14.9 0.2 1.2 8.3 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) NARP1 PF12569.3 CAR26047.1 - 1.2 7.7 10.8 1.8 7.2 7.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CHCH PF06747.8 CAR26048.1 - 0.00043 20.1 2.1 0.00074 19.3 1.5 1.4 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 CAR26048.1 - 0.013 15.5 2.8 0.031 14.3 1.9 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 CAR26048.1 - 0.033 13.9 2.2 0.045 13.5 1.5 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.7 CAR26048.1 - 0.72 9.7 3.2 8.3 6.3 0.2 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Pkinase PF00069.20 CAR26049.1 - 9.6e-46 156.0 0.0 3.7e-45 154.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR26049.1 - 1.3e-16 60.4 0.0 2.8e-16 59.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CAR26049.1 - 0.1 11.6 0.0 0.26 10.3 0.0 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribonucleas_3_3 PF14622.1 CAR26051.1 - 1.2e-21 76.9 0.0 2.1e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 CAR26051.1 - 0.00036 20.9 0.1 0.0012 19.2 0.0 2.0 2 1 0 2 2 2 1 Ribonuclease III domain GIT_SHD PF08518.6 CAR26052.1 - 1.9e-22 78.2 15.1 4e-12 45.2 0.0 3.6 4 0 0 4 4 4 2 Spa2 homology domain (SHD) of GIT HALZ PF02183.13 CAR26052.1 - 0.00043 19.9 10.4 0.027 14.1 0.2 3.1 3 0 0 3 3 3 2 Homeobox associated leucine zipper bZIP_1 PF00170.16 CAR26052.1 - 0.01 15.7 6.6 0.96 9.4 0.4 3.3 2 0 0 2 2 2 0 bZIP transcription factor DivIC PF04977.10 CAR26052.1 - 0.013 14.9 5.6 1.9 8.0 0.2 3.6 2 0 0 2 2 2 0 Septum formation initiator FlaC_arch PF05377.6 CAR26052.1 - 0.12 12.3 3.6 2.8 7.8 0.4 3.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) E1-E2_ATPase PF00122.15 CAR26053.1 - 1.3e-48 165.0 0.0 3.4e-48 163.6 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CAR26053.1 - 2.4e-38 132.7 0.0 4.3e-38 131.8 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 CAR26053.1 - 7.3e-24 83.6 2.9 4.2e-08 33.2 0.0 5.8 6 0 0 6 6 6 3 Heavy-metal-associated domain HAD PF12710.2 CAR26053.1 - 7e-20 71.9 0.0 1.5e-19 70.9 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CAR26053.1 - 5.6e-07 29.3 0.0 0.00032 20.3 0.0 2.6 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Tox-PL-2 PF15643.1 CAR26053.1 - 0.22 11.5 4.5 3.9 7.5 0.0 4.0 4 1 1 5 5 5 0 Papain fold toxin 2 DUF678 PF05077.7 CAR26053.1 - 0.28 11.2 1.7 13 5.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF678) DUF3795 PF12675.2 CAR26053.1 - 8 6.7 8.6 9.2 6.5 1.3 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3795) Septin PF00735.13 CAR26054.1 - 2.4e-112 374.5 0.8 2.4e-112 374.5 0.6 1.9 2 1 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 CAR26054.1 - 8.9e-05 22.4 0.1 0.00038 20.3 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CAR26054.1 - 0.0037 16.4 0.7 0.011 14.9 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 CAR26054.1 - 0.06 13.3 0.3 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Exonuc_VII_L PF02601.10 CAR26054.1 - 0.36 9.9 6.8 0.68 9.0 4.7 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Dynamin_N PF00350.18 CAR26054.1 - 1 9.1 8.0 1.2 8.9 0.4 3.2 2 1 0 2 2 2 0 Dynamin family GTP_EFTU PF00009.22 CAR26054.1 - 1.5 8.2 4.0 1.2 8.5 0.0 2.6 3 1 0 3 3 3 0 Elongation factor Tu GTP binding domain MAP7 PF05672.6 CAR26054.1 - 1.6 8.0 19.0 3.4 7.0 13.1 1.4 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family DUF342 PF03961.8 CAR26054.1 - 4 5.7 10.3 6.9 4.9 7.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 CAR26054.1 - 5.3 6.5 15.2 9.5 5.7 10.6 1.4 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 CAR26054.1 - 8.2 4.1 11.5 13 3.4 8.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TPR_11 PF13414.1 CAR26055.1 - 2.2e-09 36.7 3.0 8.7e-07 28.4 0.6 2.8 2 1 0 2 2 2 2 TPR repeat SHNi-TPR PF10516.4 CAR26055.1 - 1.1e-08 34.1 0.4 1.1e-08 34.1 0.3 2.3 2 0 0 2 2 2 1 SHNi-TPR TPR_16 PF13432.1 CAR26055.1 - 1.5e-06 28.7 3.6 6.7e-05 23.4 0.8 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 CAR26055.1 - 3.2e-05 23.7 4.2 0.036 13.9 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 CAR26055.1 - 3.4e-05 24.0 1.2 3.4e-05 24.0 0.9 3.0 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 CAR26055.1 - 9.9e-05 22.1 1.0 0.14 12.0 0.3 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CAR26055.1 - 0.00029 21.1 2.5 0.11 13.2 0.1 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 CAR26055.1 - 0.00037 20.0 3.3 0.29 11.0 0.1 3.8 2 2 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 CAR26055.1 - 0.0021 17.8 7.5 2.4 8.2 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 CAR26055.1 - 0.0052 17.1 3.1 1.1 9.9 0.0 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CAR26055.1 - 0.045 13.8 2.2 0.13 12.4 0.3 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 CAR26055.1 - 0.051 13.7 3.6 0.23 11.7 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2411 PF10304.4 CAR26055.1 - 0.052 13.1 1.2 0.15 11.6 0.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF2411) TPR_8 PF13181.1 CAR26055.1 - 1.5 8.8 10.5 8.3 6.4 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 CAR26055.1 - 1.6 8.4 9.1 17 5.1 0.2 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat Vps16_C PF04840.7 CAR26055.1 - 1.9 7.3 9.3 0.056 12.3 1.7 1.8 2 0 0 2 2 2 0 Vps16, C-terminal region UPF0121 PF03661.8 CAR26056.1 - 5e-10 38.9 7.2 6.6e-10 38.6 5.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) HSP70 PF00012.15 CAR26057.1 - 2.1e-271 901.1 7.7 2.4e-271 900.9 5.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CAR26057.1 - 9.9e-17 60.5 0.0 1.9e-15 56.3 0.0 2.3 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 CAR26057.1 - 0.0061 16.1 0.0 0.016 14.8 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 CAR26057.1 - 0.013 14.3 0.3 0.086 11.6 0.1 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 CAR26057.1 - 0.024 13.7 1.2 0.081 12.0 0.0 2.4 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase DUF1484 PF07363.6 CAR26057.1 - 0.24 11.7 1.6 15 6.0 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1484) NPR3 PF03666.8 CAR26058.1 - 1.5e-152 508.3 0.5 1.5e-152 508.3 0.4 2.6 3 0 0 3 3 3 1 Nitrogen Permease regulator of amino acid transport activity 3 RRM_1 PF00076.17 CAR26059.1 - 9.7e-28 95.6 5.7 6.6e-14 51.2 0.2 4.3 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR26059.1 - 5e-19 67.8 0.4 2.4e-07 30.5 0.1 3.7 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR26059.1 - 2.5e-18 65.8 0.2 9.8e-08 31.8 0.1 3.4 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CAR26059.1 - 3.6e-05 23.4 0.1 0.45 10.3 0.0 3.3 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif AAA_2 PF07724.9 CAR26060.1 - 3e-46 157.4 0.0 1.3e-44 152.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 CAR26060.1 - 2.2e-25 89.3 0.2 4.5e-14 52.7 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 CAR26060.1 - 4.5e-24 84.1 1.4 1.9e-23 82.1 0.9 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.15 CAR26060.1 - 7.5e-18 64.2 2.8 9.3e-12 44.6 0.2 3.1 2 0 0 2 2 2 2 Clp amino terminal domain AAA_5 PF07728.9 CAR26060.1 - 1.3e-16 60.6 0.1 1.6e-08 34.3 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 CAR26060.1 - 4.2e-11 42.6 0.1 2.9e-08 33.3 0.0 2.7 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.1 CAR26060.1 - 3.5e-09 36.9 12.0 0.00026 21.0 0.0 5.7 4 3 3 7 7 6 2 AAA ATPase domain AAA_22 PF13401.1 CAR26060.1 - 5.9e-09 36.1 0.7 0.0078 16.3 0.0 4.0 3 1 0 3 3 3 2 AAA domain TIP49 PF06068.8 CAR26060.1 - 2.4e-05 23.2 2.8 0.037 12.7 0.0 4.1 4 0 0 4 4 4 1 TIP49 C-terminus Mg_chelatase PF01078.16 CAR26060.1 - 0.00014 21.0 0.0 0.54 9.3 0.0 3.6 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI NACHT PF05729.7 CAR26060.1 - 0.00015 21.4 0.0 0.78 9.3 0.0 2.8 2 0 0 2 2 2 2 NACHT domain AAA_33 PF13671.1 CAR26060.1 - 0.00027 20.8 1.0 0.16 11.8 0.0 4.0 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 CAR26060.1 - 0.00046 19.3 0.7 0.056 12.5 0.0 3.7 3 0 0 3 3 3 1 Zeta toxin AAA_19 PF13245.1 CAR26060.1 - 0.00083 19.0 0.0 0.65 9.7 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_3 PF07726.6 CAR26060.1 - 0.0013 18.3 0.0 0.16 11.6 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CAR26060.1 - 0.0016 19.2 8.3 0.26 12.1 0.0 4.4 4 1 0 4 4 3 2 AAA domain Torsin PF06309.6 CAR26060.1 - 0.0085 15.9 0.0 0.045 13.6 0.0 2.1 2 0 0 2 2 2 1 Torsin AAA_18 PF13238.1 CAR26060.1 - 0.018 15.3 1.7 7 6.9 0.0 3.9 3 0 0 3 3 3 0 AAA domain DUF4407 PF14362.1 CAR26060.1 - 0.02 13.8 3.9 0.036 13.0 2.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IstB_IS21 PF01695.12 CAR26060.1 - 0.022 14.1 0.0 1.1 8.6 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein MobB PF03205.9 CAR26060.1 - 0.038 13.7 0.0 8.3 6.1 0.0 3.2 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B PEPCK_ATP PF01293.15 CAR26060.1 - 0.057 11.9 0.0 0.14 10.6 0.0 1.5 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase DUF3793 PF12672.2 CAR26060.1 - 0.086 12.4 0.9 0.53 9.8 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3793) Uds1 PF15456.1 CAR26060.1 - 0.31 11.0 19.3 0.061 13.3 9.5 2.6 3 0 0 3 3 2 0 Up-regulated During Septation ABC_tran PF00005.22 CAR26060.1 - 0.6 10.4 5.9 6.1 7.1 0.0 3.9 3 1 0 3 3 3 0 ABC transporter DUF501 PF04417.7 CAR26060.1 - 2.2 8.1 5.3 6.3 6.6 2.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF501) V_ATPase_I PF01496.14 CAR26060.1 - 5.7 4.6 8.1 9.3 3.9 5.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fe-S_biosyn PF01521.15 CAR26061.1 - 3.2e-17 62.4 0.0 5.2e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis BRF1 PF07741.8 CAR26061.1 - 5.3 7.3 8.5 4.9 7.4 5.3 1.4 1 1 0 1 1 1 0 Brf1-like TBP-binding domain MFS_1 PF07690.11 CAR26062.1 - 1.5e-36 125.8 31.9 1.5e-36 125.8 22.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CAR26062.1 - 3e-11 42.5 8.7 3e-11 42.5 6.1 2.9 2 1 1 3 3 3 3 Sugar (and other) transporter TRI12 PF06609.8 CAR26062.1 - 0.00028 19.2 5.6 0.00055 18.2 3.9 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Peptidase_M24 PF00557.19 CAR26063.1 - 2e-43 148.3 0.0 3e-43 147.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 CAR26063.1 - 4.1e-10 40.2 0.0 1.4e-09 38.5 0.0 1.9 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Phosphodiest PF01663.17 CAR26064.1 - 3.5e-14 52.9 0.1 6.4e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 CAR26064.1 - 0.00057 19.3 1.6 0.0011 18.3 1.1 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 CAR26064.1 - 0.0033 16.6 0.1 0.0058 15.8 0.1 1.3 1 0 0 1 1 1 1 Sulfatase DUF572 PF04502.8 CAR26066.1 - 1.8e-53 181.8 10.5 2.5e-53 181.4 7.3 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) APG6 PF04111.7 CAR26066.1 - 0.064 12.2 6.2 0.085 11.8 4.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Mu-like_Com PF10122.4 CAR26066.1 - 0.092 11.8 1.4 0.37 9.8 0.2 2.3 2 0 0 2 2 2 0 Mu-like prophage protein Com Aconitase PF00330.15 CAR26066.1 - 0.12 10.8 0.4 0.17 10.2 0.0 1.5 1 1 0 1 1 1 0 Aconitase family (aconitate hydratase) HAUS6_N PF14661.1 CAR26066.1 - 0.3 10.3 5.8 0.45 9.8 4.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DDE_Tnp_IS240 PF13610.1 CAR26066.1 - 0.34 10.8 3.4 0.55 10.1 1.4 2.0 2 1 0 2 2 2 0 DDE domain bZIP_1 PF00170.16 CAR26067.1 - 1.6e-06 27.9 21.2 3e-06 27.0 14.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor Glutaredoxin2_C PF04399.8 CAR26067.1 - 0.00062 19.3 2.3 0.0012 18.3 1.6 1.5 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain bZIP_Maf PF03131.12 CAR26067.1 - 0.0065 16.7 11.6 0.011 15.9 8.0 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF1423 PF07227.6 CAR26067.1 - 0.013 14.1 1.9 0.018 13.7 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) IpaD PF06511.6 CAR26067.1 - 0.025 13.5 2.4 0.033 13.1 1.7 1.1 1 0 0 1 1 1 0 Invasion plasmid antigen IpaD TPR_MLP1_2 PF07926.7 CAR26067.1 - 0.035 13.8 10.5 0.061 13.0 7.3 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.14 CAR26067.1 - 0.097 10.5 0.9 0.1 10.4 0.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 CAR26067.1 - 0.31 9.3 3.9 0.48 8.7 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2058 PF09831.4 CAR26067.1 - 0.58 10.0 6.0 0.53 10.1 3.1 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) APG6 PF04111.7 CAR26067.1 - 2.3 7.2 8.1 3.4 6.6 5.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 CASP_C PF08172.7 CAR26067.1 - 6.9 5.6 11.4 11 4.9 7.9 1.4 1 1 0 1 1 1 0 CASP C terminal Smr PF01713.16 CAR26068.1 - 4.7e-15 55.5 0.0 1.1e-14 54.3 0.0 1.7 1 0 0 1 1 1 1 Smr domain CUE PF02845.11 CAR26068.1 - 1.2e-09 37.4 0.3 0.0048 16.3 0.1 3.5 3 0 0 3 3 3 2 CUE domain CENP-C_C PF11699.3 CAR26069.1 - 7.5e-27 93.1 1.7 1.3e-26 92.3 1.2 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.1 CAR26069.1 - 2.1e-20 73.6 3.9 2.1e-20 73.6 2.7 4.2 4 1 0 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.6 CAR26069.1 - 5.3e-06 25.8 0.0 1.3e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.13 CAR26069.1 - 0.046 13.3 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase AT_hook PF02178.14 CAR26069.1 - 0.47 10.2 6.0 1.3 8.8 4.2 1.8 1 0 0 1 1 1 0 AT hook motif Pkinase PF00069.20 CAR26070.1 - 3.6e-72 242.6 0.0 5.7e-72 241.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR26070.1 - 3.8e-48 163.8 0.0 6.2e-48 163.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 CAR26070.1 - 1.2e-20 73.6 0.0 7e-20 71.2 0.0 2.5 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 CAR26070.1 - 4.9e-05 22.4 0.0 8.3e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CAR26070.1 - 0.17 11.5 0.0 1.1 8.9 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family HECT PF00632.20 CAR26071.1 - 9.1e-75 251.7 0.1 1.4e-74 251.1 0.1 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ribosomal_L10 PF00466.15 CAR26072.1 - 1.2e-17 63.6 0.0 1.7e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 DUF3538 PF12057.3 CAR26072.1 - 0.055 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3538) Ribosomal_S2 PF00318.15 CAR26074.1 - 4.5e-60 202.4 0.0 8.5e-60 201.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S2 MazG PF03819.12 CAR26074.1 - 0.01 15.7 0.1 0.018 14.9 0.1 1.3 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain EzrA PF06160.7 CAR26074.1 - 0.013 13.6 1.5 0.018 13.2 1.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA TRAM_LAG1_CLN8 PF03798.11 CAR26075.1 - 1.4e-31 109.6 24.7 1.4e-31 109.6 17.1 2.2 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 CAR26075.1 - 4.7e-25 86.8 0.3 1.2e-24 85.5 0.2 1.8 1 0 0 1 1 1 1 TRAM1-like protein MOSP_C PF02722.10 CAR26075.1 - 0.039 13.5 0.1 0.071 12.6 0.1 1.3 1 0 0 1 1 1 0 Major Outer Sheath Protein C-terminal region Herpes_LMP1 PF05297.6 CAR26075.1 - 0.19 10.6 5.9 0.29 10.0 4.1 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) VHS PF00790.14 CAR26076.1 - 1.2e-35 122.2 0.1 3.2e-35 120.8 0.1 1.8 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.23 CAR26076.1 - 6.9e-15 54.1 0.0 1.2e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CAR26076.1 - 8.3e-13 47.7 0.1 1.4e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CAR26076.1 - 2.3e-12 46.2 0.1 6.4e-12 44.7 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain Hrs_helical PF12210.3 CAR26076.1 - 0.00048 20.3 2.4 0.0053 16.9 0.0 2.4 2 0 0 2 2 2 1 Hepatocyte growth factor-regulated tyrosine kinase substrate Slu7 PF11708.3 CAR26076.1 - 0.35 10.6 7.2 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor Herpes_DNAp_acc PF04929.7 CAR26076.1 - 0.56 9.1 5.4 1 8.2 3.7 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor F-actin_cap_A PF01267.12 CAR26077.1 - 7.6e-76 254.7 3.0 8.7e-76 254.5 2.1 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Use1 PF09753.4 CAR26078.1 - 0.0089 15.4 0.0 0.0095 15.4 0.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 SNARE PF05739.14 CAR26078.1 - 0.013 15.1 0.7 0.016 14.8 0.5 1.1 1 0 0 1 1 1 0 SNARE domain Polysacc_deac_2 PF04748.8 CAR26078.1 - 0.034 13.1 0.0 0.038 12.9 0.0 1.1 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase Ribosomal_L14e PF01929.12 CAR26079.1 - 1e-29 102.6 3.3 1.5e-29 102.1 2.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 CAR26079.1 - 0.11 12.2 0.7 0.22 11.2 0.5 1.5 1 0 0 1 1 1 0 KOW motif TFIIS_M PF07500.9 CAR26080.1 - 7.7e-23 80.7 1.3 1.4e-22 79.9 0.9 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.24 CAR26080.1 - 1.9e-10 40.2 8.2 3.3e-10 39.4 5.7 1.4 1 0 0 1 1 1 1 PHD-finger SPOC PF07744.8 CAR26080.1 - 0.0041 17.5 0.0 0.78 10.2 0.0 2.3 2 0 0 2 2 2 1 SPOC domain zf-CW PF07496.10 CAR26080.1 - 0.068 12.8 2.1 0.16 11.7 1.5 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger Mu-like_Com PF10122.4 CAR26080.1 - 0.14 11.2 1.8 52 2.9 0.1 3.4 3 0 0 3 3 3 0 Mu-like prophage protein Com PHD_2 PF13831.1 CAR26080.1 - 1.3 8.3 5.1 5 6.5 3.5 2.0 1 1 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 CAR26080.1 - 3.2 7.5 11.9 1.9 8.2 4.5 2.6 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 PAP2 PF01569.16 CAR26081.1 - 8e-12 44.9 4.8 8e-12 44.9 3.3 2.4 2 0 0 2 2 2 2 PAP2 superfamily PAP2_3 PF14378.1 CAR26081.1 - 2.7e-05 23.7 4.3 2.7e-05 23.7 3.0 2.0 2 0 0 2 2 2 1 PAP2 superfamily Ribosomal_S6 PF01250.12 CAR26082.1 - 9.6e-08 31.7 0.0 1.4e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S6 Calici_MSP PF05752.6 CAR26082.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Calicivirus minor structural protein Snf7 PF03357.16 CAR26083.1 - 1.5e-31 109.1 25.0 4.5e-31 107.5 15.6 2.0 2 0 0 2 2 2 1 Snf7 Ist1 PF03398.9 CAR26083.1 - 5e-05 22.7 7.9 6.6e-05 22.3 5.4 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway S-methyl_trans PF02574.11 CAR26083.1 - 0.066 12.5 0.5 0.097 11.9 0.3 1.2 1 0 0 1 1 1 0 Homocysteine S-methyltransferase Uds1 PF15456.1 CAR26083.1 - 1.1 9.2 14.0 0.037 14.0 1.0 2.6 1 1 1 2 2 2 0 Up-regulated During Septation DUF87 PF01935.12 CAR26083.1 - 2 8.1 11.1 1 9.1 0.3 2.1 1 1 0 2 2 2 0 Domain of unknown function DUF87 DUF1002 PF06207.6 CAR26083.1 - 2.1 7.5 12.9 0.13 11.5 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1002) APS_kinase PF01583.15 CAR26084.1 - 4.6e-74 247.3 0.0 5.5e-74 247.0 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 CAR26084.1 - 9.6e-09 35.2 0.0 1.6e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CAR26084.1 - 4.5e-05 24.2 0.1 7.9e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CAR26084.1 - 8.9e-05 22.8 0.1 0.00026 21.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 CAR26084.1 - 0.00016 20.9 0.0 0.00019 20.7 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 CAR26084.1 - 0.00049 19.5 0.0 0.00078 18.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain CPT PF07931.7 CAR26084.1 - 0.011 15.3 0.5 0.21 11.1 0.3 2.4 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_23 PF13476.1 CAR26084.1 - 0.021 15.1 0.2 0.026 14.8 0.1 1.3 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.1 CAR26084.1 - 0.024 14.6 0.1 0.027 14.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain PRK PF00485.13 CAR26084.1 - 0.056 12.9 0.0 0.08 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.1 CAR26084.1 - 0.059 13.3 0.1 0.082 12.8 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 CAR26084.1 - 0.068 13.4 0.0 0.087 13.1 0.0 1.3 1 0 0 1 1 1 0 ABC transporter G-alpha PF00503.15 CAR26084.1 - 0.11 11.1 0.2 0.17 10.5 0.1 1.3 1 1 0 1 1 1 0 G-protein alpha subunit YozD PF14162.1 CAR26084.1 - 0.13 12.3 0.4 0.37 10.8 0.0 1.8 2 0 0 2 2 2 0 YozD-like protein Dynamin_M PF01031.15 CAR26085.1 - 4.6e-103 344.0 0.1 1.1e-102 342.8 0.0 1.6 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 CAR26085.1 - 2.1e-55 187.1 0.1 4.6e-55 185.9 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 CAR26085.1 - 2.4e-27 94.6 4.3 6.7e-27 93.2 3.0 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 CAR26085.1 - 0.00044 20.1 0.2 0.012 15.5 0.2 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CAR26085.1 - 0.0097 16.3 0.1 0.026 15.0 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein PAP_central PF04928.12 CAR26086.1 - 3.5e-108 360.2 0.0 5.7e-108 359.5 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 CAR26086.1 - 5e-48 162.5 2.9 9.6e-48 161.6 2.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 CAR26086.1 - 7.9e-12 45.3 0.0 3.1e-11 43.4 0.0 2.0 1 0 0 1 1 1 1 Nucleotidyltransferase domain Oxysterol_BP PF01237.13 CAR26087.1 - 2.1e-90 302.7 0.0 2.6e-90 302.4 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein PA_decarbox PF05870.6 CAR26088.1 - 0.0025 17.3 0.0 0.005 16.3 0.0 1.5 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) Ribosomal_L50 PF10501.4 CAR26090.1 - 1.1e-23 83.3 0.2 1.1e-23 83.3 0.1 1.7 2 0 0 2 2 2 1 Ribosomal subunit 39S PAS_10 PF13596.1 CAR26090.1 - 0.19 11.9 1.5 0.81 9.9 0.1 2.4 2 1 0 2 2 2 0 PAS domain DUF1044 PF06296.7 CAR26090.1 - 0.46 10.3 4.7 11 5.8 0.1 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF1044) LAMTOR PF15454.1 CAR26091.1 - 9.8e-11 41.7 4.8 1.3e-10 41.3 2.9 1.6 1 1 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF3552 PF12072.3 CAR26091.1 - 0.018 14.2 0.4 0.018 14.2 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) PSI_PsaH PF03244.9 CAR26091.1 - 0.03 13.5 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VI DUF2762 PF10960.3 CAR26091.1 - 0.1 12.2 0.8 0.21 11.3 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) PPR_1 PF12854.2 CAR26091.1 - 0.12 11.8 0.3 0.2 11.1 0.2 1.4 1 0 0 1 1 1 0 PPR repeat DUF2733 PF10813.3 CAR26091.1 - 0.17 11.4 1.5 0.36 10.4 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2733) SynMuv_product PF06047.6 CAR26091.1 - 0.19 11.4 3.2 0.52 10.0 0.2 2.0 2 0 0 2 2 2 0 Ras-induced vulval development antagonist Hemolysin_N PF12563.3 CAR26091.1 - 0.39 10.1 2.8 0.37 10.1 0.8 1.8 1 1 0 2 2 2 0 Hemolytic toxin N terminal Bromodomain PF00439.20 CAR26092.1 - 4.6e-33 112.9 4.4 2.2e-19 69.1 0.1 2.7 2 0 0 2 2 2 2 Bromodomain Glyco_transf_15 PF01793.11 CAR26093.1 - 3.6e-126 420.6 10.2 4.5e-126 420.2 7.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Peptidase_M75 PF09375.5 CAR26093.1 - 0.1 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Imelysin QCR10 PF09796.4 CAR26094.1 - 2.3e-29 100.8 0.9 2.7e-29 100.6 0.6 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) RhodobacterPufX PF11511.3 CAR26094.1 - 0.045 13.1 1.9 0.084 12.2 1.1 1.6 1 1 0 1 1 1 0 Intrinsic membrane protein PufX adh_short PF00106.20 CAR26095.1 - 7.6e-64 214.6 3.4 7.5e-33 113.8 0.7 2.6 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 CAR26095.1 - 1.8e-32 112.4 0.6 2.5e-16 59.8 0.1 2.4 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 CAR26095.1 - 6.9e-30 102.9 0.0 1.3e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 CAR26095.1 - 6.3e-09 35.7 0.0 6.6e-06 25.9 0.0 2.8 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase DUF4397 PF14344.1 CAR26095.1 - 0.016 15.5 0.1 5.7 7.2 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4397) Adap_comp_sub PF00928.16 CAR26096.1 - 2.9e-31 108.5 0.0 5e-31 107.7 0.0 1.4 1 1 0 1 1 1 1 Adaptor complexes medium subunit family SNF5 PF04855.7 CAR26097.1 - 4.8e-69 232.5 2.6 4.8e-69 232.5 1.8 4.0 3 2 0 3 3 3 1 SNF5 / SMARCB1 / INI1 Mcm10 PF09332.6 CAR26097.1 - 2.3 7.5 0.0 2.3 7.5 0.0 3.3 2 1 1 3 3 3 0 Mcm10 replication factor DUF2370 PF10176.4 CAR26098.1 - 6.6e-75 251.4 0.0 8e-75 251.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Mito_carr PF00153.22 CAR26099.1 - 1.7e-61 203.9 2.5 1.6e-22 78.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 CAR26099.1 - 0.018 15.0 3.2 0.5 10.4 0.0 3.3 3 2 1 4 4 4 0 Tim17/Tim22/Tim23/Pmp24 family YtxH PF12732.2 CAR26099.1 - 4.5 7.7 5.2 23 5.4 0.0 3.1 3 0 0 3 3 3 0 YtxH-like protein Mito_carr PF00153.22 CAR26100.1 - 2e-61 203.6 1.4 7.2e-22 76.9 0.0 3.7 3 1 1 4 4 4 3 Mitochondrial carrier protein ThiF PF00899.16 CAR26101.1 - 4.6e-37 126.8 0.0 8.3e-37 126.0 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 CAR26101.1 - 0.00098 19.2 0.0 0.0019 18.2 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 CAR26101.1 - 0.0077 15.2 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase XdhC_C PF13478.1 CAR26101.1 - 0.011 16.0 0.0 0.052 13.8 0.0 2.1 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_binding_7 PF13241.1 CAR26101.1 - 0.025 14.8 0.0 0.058 13.6 0.0 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.13 CAR26101.1 - 0.046 13.7 0.2 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain ApbA PF02558.11 CAR26101.1 - 0.053 12.9 0.0 0.099 12.0 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DAO PF01266.19 CAR26101.1 - 0.15 10.9 0.1 0.39 9.5 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase TFIIE_alpha PF02002.12 CAR26102.1 - 6.9e-33 112.3 0.1 2.6e-32 110.4 0.0 2.0 2 0 0 2 2 2 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.7 CAR26102.1 - 4.9e-11 41.7 0.4 1.4e-10 40.3 0.3 1.9 1 0 0 1 1 1 1 TFIIB zinc-binding DAO PF01266.19 CAR26103.1 - 9.2e-22 77.4 0.0 1.2e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 CAR26103.1 - 0.071 11.7 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Malic_M PF03949.10 CAR26104.1 - 5e-76 255.6 0.0 7.7e-76 255.0 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 CAR26104.1 - 2.9e-63 212.7 0.0 4.4e-63 212.1 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain BRICHOS PF04089.9 CAR26105.1 - 0.071 12.9 2.7 0.43 10.4 0.1 3.6 2 1 1 3 3 3 0 BRICHOS domain Matrilin_ccoil PF10393.4 CAR26105.1 - 3.1 7.2 11.6 0.055 12.8 0.7 3.8 4 0 0 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF869 PF05911.6 CAR26105.1 - 8.7 4.4 77.1 0.33 9.1 21.6 3.6 1 1 3 4 4 4 0 Plant protein of unknown function (DUF869) NIF PF03031.13 CAR26106.1 - 2.5e-51 173.4 0.1 3.8e-51 172.9 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Molydop_binding PF01568.16 CAR26106.1 - 0.022 14.5 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain Leuk-A4-hydro_C PF09127.6 CAR26106.1 - 0.057 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal Acetyltransf_1 PF00583.19 CAR26107.1 - 3.8e-15 55.6 0.0 6.1e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CAR26107.1 - 2.5e-10 40.3 0.2 4.6e-10 39.5 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CAR26107.1 - 6.1e-08 32.7 0.0 7.9e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CAR26107.1 - 0.0016 18.4 0.3 0.0024 17.8 0.2 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CAR26107.1 - 0.0024 17.7 0.0 0.0029 17.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CAR26107.1 - 0.0046 16.8 0.0 0.0075 16.1 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CAR26107.1 - 0.006 16.7 0.2 0.0075 16.4 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CAR26107.1 - 0.0062 16.2 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein zf-C2H2 PF00096.21 CAR26108.1 - 2.6e-05 24.2 3.4 2.6e-05 24.2 2.4 2.6 3 0 0 3 3 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CAR26108.1 - 5.7e-05 23.1 2.2 5.7e-05 23.1 1.6 2.9 3 0 0 3 3 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 CAR26108.1 - 0.00025 21.1 2.9 0.0006 19.8 2.0 1.7 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.6 CAR26108.1 - 0.027 14.0 1.1 3.1 7.4 0.2 2.4 1 1 1 2 2 2 0 GAGA factor zf-H2C2_2 PF13465.1 CAR26108.1 - 0.031 14.5 13.3 1 9.8 0.0 3.5 3 1 0 3 3 3 0 Zinc-finger double domain zf-C2H2_2 PF12756.2 CAR26108.1 - 0.05 13.7 6.3 1.4 9.0 0.8 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) TerY-C PF15616.1 CAR26108.1 - 0.069 13.0 0.1 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain DUF2225 PF09986.4 CAR26108.1 - 0.14 11.6 0.8 12 5.2 0.0 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-met PF12874.2 CAR26108.1 - 0.25 11.6 4.3 0.26 11.5 0.4 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CAR26108.1 - 0.37 10.9 3.4 0.21 11.8 0.4 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-XS PF03470.9 CAR26108.1 - 8.1 6.5 6.8 11 6.1 1.3 2.5 2 0 0 2 2 2 0 XS zinc finger domain Cg6151-P PF10233.4 CAR26109.1 - 3.2e-38 130.1 11.1 3.9e-38 129.9 7.7 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P COPI_assoc PF08507.5 CAR26109.1 - 0.0003 20.4 7.5 0.00041 20.0 5.2 1.2 1 0 0 1 1 1 1 COPI associated protein DUF1129 PF06570.6 CAR26109.1 - 9.9 5.4 8.0 29 3.8 5.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) zinc_ribbon_6 PF14599.1 CAR26110.1 - 1.4e-25 88.8 3.2 1.4e-25 88.8 2.2 4.9 3 1 2 5 5 5 1 Zinc-ribbon zf-CHY PF05495.7 CAR26110.1 - 9.1e-11 41.7 23.2 9.1e-11 41.7 16.1 4.7 3 1 0 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.1 CAR26110.1 - 5.7e-08 32.4 10.5 5.7e-08 32.4 7.3 5.1 3 2 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 CAR26110.1 - 3.8e-05 23.6 7.4 3.8e-05 23.6 5.1 5.7 3 3 3 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAR26110.1 - 0.0029 17.2 12.6 0.0029 17.2 8.7 6.6 3 2 2 6 6 6 1 zinc-RING finger domain HMG_box PF00505.14 CAR26111.1 - 3.3e-29 100.9 18.6 3.3e-17 62.4 2.8 3.4 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 CAR26111.1 - 1.1e-14 54.5 10.3 9.3e-12 45.1 2.8 3.9 5 0 0 5 5 5 2 HMG-box domain CHDNT PF08073.7 CAR26111.1 - 2.8e-06 26.8 0.2 0.0077 15.8 0.0 2.8 3 0 0 3 3 3 2 CHDNT (NUC034) domain Cyt-b5 PF00173.23 CAR26112.1 - 3.4e-19 68.4 0.1 5e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cu_amine_oxid PF01179.15 CAR26113.1 - 2.1e-151 504.3 0.1 2.6e-151 504.0 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 CAR26113.1 - 4.6e-06 26.6 0.3 1.7e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain dsDNA_bind PF01984.15 CAR26114.1 - 3.6e-24 84.7 0.0 5.1e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Double-stranded DNA-binding domain PHD PF00628.24 CAR26115.1 - 2.7e-14 52.5 21.3 2.3e-11 43.2 5.3 3.2 2 1 1 3 3 3 2 PHD-finger zf-PHD-like PF15446.1 CAR26115.1 - 0.0055 16.0 3.5 0.19 10.9 0.1 2.6 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 CAR26115.1 - 0.13 12.0 10.7 0.81 9.4 0.6 2.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.1 CAR26115.1 - 0.26 11.4 10.0 0.19 11.8 1.4 2.7 2 0 0 2 2 2 0 PHD-like zinc-binding domain Prok-RING_1 PF14446.1 CAR26115.1 - 4.8 6.9 13.3 1.4 8.7 2.6 2.9 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 HEAT PF02985.17 CAR26116.1 - 0.011 15.7 1.0 37 4.7 0.0 4.8 5 0 0 5 5 5 0 HEAT repeat HEAT_2 PF13646.1 CAR26116.1 - 0.031 14.5 0.5 0.53 10.6 0.1 3.1 3 0 0 3 3 3 0 HEAT repeats HEAT_EZ PF13513.1 CAR26116.1 - 0.19 12.2 1.0 7.4 7.1 0.0 3.9 4 0 0 4 4 4 0 HEAT-like repeat Form_Nir_trans PF01226.12 CAR26117.1 - 1.4e-62 210.9 16.7 1.6e-62 210.6 11.6 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter DUF2890 PF11081.3 CAR26117.1 - 0.72 9.8 12.7 0.035 14.1 4.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Arm PF00514.18 CAR26118.1 - 0.036 13.8 0.6 4.8 7.1 0.1 3.6 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat BRAP2 PF07576.7 CAR26119.1 - 2.1e-27 94.8 1.2 5.4e-27 93.5 0.9 1.6 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 CAR26119.1 - 1.2e-21 76.5 6.8 3.5e-21 75.0 4.7 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 CAR26119.1 - 1.4e-10 40.8 10.6 1.4e-10 40.8 7.4 2.1 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.1 CAR26119.1 - 8.1e-06 25.4 9.1 8.1e-06 25.4 6.3 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CAR26119.1 - 9.5e-06 25.1 7.0 9.5e-06 25.1 4.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CAR26119.1 - 1.4e-05 24.6 10.8 4.1e-05 23.1 7.5 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAR26119.1 - 2.5e-05 24.2 10.5 2.5e-05 24.2 7.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CAR26119.1 - 0.00027 20.5 5.9 0.00037 20.1 2.9 2.2 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 CAR26119.1 - 0.00032 20.7 6.8 0.00032 20.7 4.7 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CAR26119.1 - 0.0011 18.6 4.7 0.004 16.9 3.3 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_RING PF05883.6 CAR26119.1 - 0.015 15.1 1.3 0.053 13.3 0.9 1.9 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_4 PF14570.1 CAR26119.1 - 0.029 13.9 8.7 0.069 12.7 6.0 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 CAR26119.1 - 0.84 9.2 8.9 15 5.1 3.4 2.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DUF1635 PF07795.6 CAR26119.1 - 1.4 8.2 15.5 3.8 6.8 10.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Pribosyl_synth PF14572.1 CAR26120.1 - 1.7e-41 141.9 3.5 1.7e-36 125.6 1.4 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 CAR26120.1 - 3.9e-38 129.7 0.2 1.2e-37 128.1 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 CAR26120.1 - 7.6e-12 45.0 1.1 1.7e-11 43.9 0.6 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CAR26120.1 - 0.013 14.7 0.1 0.02 14.1 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase DUF218 PF02698.12 CAR26120.1 - 0.06 12.8 0.0 0.16 11.4 0.0 1.8 2 0 0 2 2 2 0 DUF218 domain HAD_2 PF13419.1 CAR26121.1 - 5.2e-13 49.5 0.0 6.1e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CAR26121.1 - 1.5e-08 35.3 0.0 1.9e-08 35.0 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 CAR26121.1 - 0.0035 17.1 0.0 0.007 16.2 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 CAR26121.1 - 0.0082 16.3 0.0 0.011 15.8 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase RRM_1 PF00076.17 CAR26122.1 - 7.2e-13 47.9 0.0 1.5e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR26122.1 - 3.3e-10 39.7 0.0 6.3e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR26122.1 - 1.3e-05 24.9 0.0 2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 CAR26122.1 - 0.009 16.4 1.0 0.009 16.4 0.7 3.1 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 Mfp-3 PF04202.8 CAR26123.1 - 0.14 12.3 0.1 0.23 11.6 0.0 1.5 1 1 0 1 1 1 0 Foot protein 3 Mito_carr PF00153.22 CAR26124.1 - 2.4e-45 152.1 4.5 1.8e-16 59.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.22 CAR26125.1 - 2.3e-59 197.1 2.3 2.5e-21 75.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_60s PF00428.14 CAR26126.1 - 1.3e-24 86.3 16.4 1.6e-24 86.1 11.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2714 PF10896.3 CAR26127.1 - 0.03 14.1 0.1 0.067 13.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2714) FANCI_HD1 PF14679.1 CAR26127.1 - 0.13 11.9 0.3 0.13 11.9 0.2 1.7 2 0 0 2 2 2 0 FANCI helical domain 1 Noelin-1 PF12308.3 CAR26127.1 - 0.19 11.5 3.9 0.3 10.9 1.2 2.1 1 1 1 2 2 2 0 Neurogenesis glycoprotein DUF4239 PF14023.1 CAR26127.1 - 0.22 10.8 0.8 0.35 10.1 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4239) Grp1_Fun34_YaaH PF01184.14 CAR26128.1 - 2.6e-63 213.1 13.0 3e-63 212.9 9.0 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family WD40 PF00400.27 CAR26130.1 - 5e-15 54.7 6.1 1.9e-06 27.5 0.1 5.7 6 0 0 6 6 6 2 WD domain, G-beta repeat Nup160 PF11715.3 CAR26130.1 - 0.0055 14.9 0.3 0.0082 14.3 0.2 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 PQQ_3 PF13570.1 CAR26130.1 - 0.013 15.8 0.0 0.087 13.1 0.0 2.4 2 0 0 2 2 2 0 PQQ-like domain NMT PF01233.14 CAR26131.1 - 4.9e-82 273.3 0.1 7.8e-82 272.6 0.1 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 CAR26131.1 - 3e-77 258.3 0.0 5.3e-77 257.5 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 CAR26131.1 - 5.8e-08 32.6 0.0 2.2e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CAR26131.1 - 3.8e-05 23.8 0.0 0.011 15.9 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CAR26131.1 - 0.00096 19.2 0.0 0.0024 18.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CAR26131.1 - 0.0044 17.0 0.0 0.018 15.0 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Pox_A12 PF04651.8 CAR26132.1 - 7.9 6.5 12.0 0.49 10.4 4.3 1.8 1 1 1 2 2 2 0 Poxvirus A12 protein PRELI PF04707.9 CAR26133.1 - 5.5e-50 168.9 0.1 6.6e-50 168.7 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family Fungal_trans_2 PF11951.3 CAR26134.1 - 3.3e-70 236.6 10.0 3.9e-70 236.3 6.9 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR26134.1 - 4.5e-09 36.0 7.4 8e-09 35.2 5.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 CAR26134.1 - 0.51 10.5 9.5 0.51 10.5 5.0 2.3 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Glu_synthase PF01645.12 CAR26135.1 - 8.1e-156 518.5 0.0 1.3e-155 517.8 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 CAR26135.1 - 5e-140 466.2 0.0 8.3e-140 465.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 CAR26135.1 - 5.7e-116 386.8 0.0 3.2e-115 384.3 0.0 2.2 2 1 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.14 CAR26135.1 - 1.4e-56 190.7 1.0 2.6e-56 189.8 0.7 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 CAR26135.1 - 1.2e-24 86.0 0.1 2.2e-24 85.1 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 CAR26135.1 - 4e-15 56.2 0.0 1.5e-14 54.3 0.0 2.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CAR26135.1 - 4.5e-09 36.2 0.0 1.5e-08 34.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CAR26135.1 - 1.3e-08 35.1 0.1 0.00058 19.9 0.0 2.8 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CAR26135.1 - 4.8e-07 29.0 0.2 1.4e-05 24.1 0.1 2.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 CAR26135.1 - 1.1e-06 28.8 0.6 7.4e-05 23.0 0.0 3.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 CAR26135.1 - 1.4e-06 27.6 0.0 3.4e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 CAR26135.1 - 2.4e-05 22.9 1.4 2.7e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 CAR26135.1 - 0.00011 21.4 0.0 0.00022 20.4 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 CAR26135.1 - 0.00014 21.0 0.1 0.00046 19.3 0.0 1.9 2 0 0 2 2 1 1 Thi4 family FAD_binding_2 PF00890.19 CAR26135.1 - 0.00019 20.4 0.1 0.00034 19.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 CAR26135.1 - 0.00082 18.5 0.0 0.0016 17.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 CAR26135.1 - 0.0022 16.9 0.2 0.013 14.3 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FMO-like PF00743.14 CAR26135.1 - 0.0027 15.9 0.2 0.27 9.3 0.0 3.0 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_Gly3P_dh_N PF01210.18 CAR26135.1 - 0.0035 17.0 0.0 0.01 15.6 0.0 1.8 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF4538 PF15061.1 CAR26135.1 - 0.004 16.4 0.1 0.013 14.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4538) GATase_6 PF13522.1 CAR26135.1 - 0.016 15.2 0.0 0.068 13.1 0.0 2.0 2 0 0 2 2 2 0 Glutamine amidotransferase domain NAD_binding_9 PF13454.1 CAR26135.1 - 0.017 14.8 0.0 0.12 12.1 0.0 2.5 3 0 0 3 3 1 0 FAD-NAD(P)-binding AdoHcyase_NAD PF00670.16 CAR26135.1 - 0.019 14.8 1.0 3.8 7.3 0.0 3.0 3 0 0 3 3 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_10 PF13460.1 CAR26135.1 - 0.032 14.2 0.3 0.27 11.1 0.0 2.3 2 0 0 2 2 2 0 NADH(P)-binding NAD_binding_7 PF13241.1 CAR26135.1 - 0.037 14.2 0.8 1.7 8.9 0.0 2.8 2 0 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 CAR26135.1 - 0.057 13.0 0.1 0.19 11.3 0.0 2.0 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.4 CAR26135.1 - 0.065 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Rossmann-like domain 2-Hacid_dh_C PF02826.14 CAR26135.1 - 0.088 11.9 0.0 2.9 6.9 0.0 2.9 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 CAR26135.1 - 0.098 12.2 0.1 0.37 10.3 0.0 2.0 2 0 0 2 2 1 0 Alanine dehydrogenase/PNT, C-terminal domain FMN_dh PF01070.13 CAR26135.1 - 0.17 10.7 5.9 0.085 11.6 0.8 2.6 3 0 0 3 3 3 0 FMN-dependent dehydrogenase DUF3602 PF12223.3 CAR26136.1 - 1.1e-19 70.5 15.2 1.3e-13 51.0 0.2 3.5 1 1 1 3 3 3 3 Protein of unknown function (DUF3602) DUF1633 PF07794.6 CAR26136.1 - 0.063 11.2 1.3 0.068 11.1 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) eIF3_subunit PF08597.5 CAR26137.1 - 3e-59 200.5 17.6 5.1e-59 199.8 12.2 1.3 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit FAD-oxidase_C PF02913.14 CAR26138.1 - 4.1e-57 193.3 0.0 6.7e-57 192.6 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CAR26138.1 - 5.2e-38 129.6 0.0 1e-37 128.7 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Peroxin-13_N PF04088.8 CAR26140.1 - 6.8e-56 188.6 0.7 1.1e-55 187.9 0.5 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.23 CAR26140.1 - 6.7e-09 34.9 0.0 1.2e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CAR26140.1 - 2.1e-08 33.5 0.0 3.5e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CAR26140.1 - 5.4e-07 28.9 0.0 9.7e-07 28.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 CAR26140.1 - 0.017 15.2 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain MMR1 PF08505.5 CAR26141.1 - 1.8e-94 316.1 26.3 1.8e-94 316.1 18.3 2.3 3 0 0 3 3 3 1 Mitochondrial Myo2 receptor-related protein bZIP_1 PF00170.16 CAR26141.1 - 0.042 13.8 6.6 1 9.3 0.2 2.8 2 0 0 2 2 2 0 bZIP transcription factor DUF4476 PF14771.1 CAR26142.1 - 0.025 14.5 0.1 0.028 14.4 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) RAG1 PF12940.2 CAR26142.1 - 0.043 12.1 0.0 0.052 11.8 0.0 1.0 1 0 0 1 1 1 0 Recombination-activation protein 1 (RAG1) PALP PF00291.20 CAR26143.1 - 1.2e-73 248.0 0.2 1.5e-73 247.7 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 CAR26143.1 - 6.4e-41 137.8 0.0 3.2e-26 90.7 0.0 2.6 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase tRNA-synt_2b PF00587.20 CAR26144.1 - 4.8e-32 110.9 0.0 8.4e-32 110.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CAR26144.1 - 0.024 14.5 0.0 0.082 12.8 0.0 2.0 1 1 0 1 1 1 0 Anticodon binding domain tRNA-synt_2 PF00152.15 CAR26144.1 - 0.09 11.5 0.2 0.27 9.9 0.2 1.8 1 1 0 1 1 1 0 tRNA synthetases class II (D, K and N) Sec61_beta PF03911.11 CAR26145.1 - 4.4e-17 61.6 0.5 5.5e-17 61.2 0.4 1.1 1 0 0 1 1 1 1 Sec61beta family Cas_Csx9 PF09658.5 CAR26145.1 - 0.11 11.3 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csx9) Sialidase_penC PF12135.3 CAR26145.1 - 0.18 11.4 2.7 0.31 10.6 1.9 1.3 1 0 0 1 1 1 0 Sialidase enzyme penultimate C terminal domain RRM_1 PF00076.17 CAR26146.1 - 1e-07 31.4 0.1 2e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR26146.1 - 1.3e-07 31.5 0.0 2.4e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR26146.1 - 0.0004 20.1 0.0 0.00092 19.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MOZ_SAS PF01853.13 CAR26147.1 - 5.2e-78 260.6 0.4 8e-78 260.0 0.3 1.3 1 0 0 1 1 1 1 MOZ/SAS family Mtf2_C PF14061.1 CAR26147.1 - 0.029 14.2 0.1 0.068 13.0 0.1 1.6 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Cwf_Cwc_15 PF04889.7 CAR26147.1 - 0.58 9.8 20.3 1.3 8.7 14.1 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.9 CAR26147.1 - 2.9 5.8 20.2 4.4 5.2 14.0 1.2 1 0 0 1 1 1 0 CDC45-like protein TFIIA PF03153.8 CAR26147.1 - 8 6.2 25.3 12 5.6 17.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 CAR26147.1 - 8.1 4.2 29.4 12 3.6 20.4 1.1 1 0 0 1 1 1 0 Nop14-like family Myb_DNA-bind_6 PF13921.1 CAR26148.1 - 9.6e-10 38.4 0.8 9.6e-10 38.4 0.6 3.3 3 1 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CAR26148.1 - 7.1e-08 32.3 1.5 1e-05 25.4 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Ribosomal_60s PF00428.14 CAR26148.1 - 8.4 6.8 14.9 1.4 9.3 6.0 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein TatD_DNase PF01026.16 CAR26149.1 - 1.9e-36 125.5 0.0 2.5e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Auts2 PF15336.1 CAR26149.1 - 0.037 14.0 0.0 0.056 13.4 0.0 1.2 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein IFT43 PF15305.1 CAR26149.1 - 0.095 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Intraflagellar transport protein 43 PP2C PF00481.16 CAR26150.1 - 8.3e-80 267.8 0.0 1.2e-79 267.2 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Chorismate_bind PF00425.13 CAR26151.1 - 9.4e-86 287.2 0.0 2.1e-85 286.1 0.0 1.5 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 CAR26151.1 - 3.9e-29 101.4 0.1 9.2e-27 93.7 0.0 3.1 2 1 0 2 2 2 1 Anthranilate synthase component I, N terminal region POR PF01558.13 CAR26151.1 - 0.0033 17.3 0.0 0.047 13.6 0.0 2.2 2 0 0 2 2 2 1 Pyruvate ferredoxin/flavodoxin oxidoreductase DUF466 PF04328.8 CAR26151.1 - 0.023 14.5 0.0 5.5 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF466) PTH2 PF01981.11 CAR26152.1 - 4.3e-44 148.9 0.0 6.6e-44 148.3 0.0 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Myc_N PF01056.13 CAR26152.1 - 0.0016 17.6 1.7 0.002 17.3 1.2 1.1 1 0 0 1 1 1 1 Myc amino-terminal region DUF2421 PF10334.4 CAR26152.1 - 0.015 14.9 0.0 0.021 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2421) DUF4611 PF15387.1 CAR26152.1 - 0.023 14.8 2.7 0.16 12.1 2.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) AAA_27 PF13514.1 CAR26152.1 - 0.036 11.7 0.4 0.044 11.4 0.2 1.0 1 0 0 1 1 1 0 AAA domain AF1Q PF15017.1 CAR26152.1 - 0.8 9.6 5.9 1.2 9.1 4.1 1.2 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator RNA_pol_3_Rpc31 PF11705.3 CAR26152.1 - 0.86 9.4 7.8 1.2 9.0 5.4 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CENP-B_dimeris PF09026.5 CAR26152.1 - 0.9 9.8 8.4 1.5 9.1 5.8 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 CAR26152.1 - 1.5 8.3 9.0 2.4 7.6 6.2 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF2457 PF10446.4 CAR26152.1 - 1.6 7.3 7.6 2.1 6.9 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PBP1_TM PF14812.1 CAR26152.1 - 2.1 8.6 6.8 3.4 8.0 4.7 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Vpu PF00558.14 CAR26152.1 - 3.3 7.3 6.5 7.3 6.2 4.5 1.5 1 0 0 1 1 1 0 Vpu protein DUF4366 PF14283.1 CAR26152.1 - 4.6 6.5 6.9 10 5.4 4.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Nop53 PF07767.6 CAR26152.1 - 8.7 5.2 8.9 0.49 9.3 2.7 1.4 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) SEP PF08059.8 CAR26153.1 - 8e-26 90.1 0.2 8e-26 90.1 0.2 2.8 3 0 0 3 3 3 1 SEP domain UBX PF00789.15 CAR26153.1 - 1.9e-16 59.8 0.0 3.5e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 CAR26153.1 - 2.4e-06 26.9 1.8 4e-06 26.2 1.2 1.4 1 0 0 1 1 1 1 UBA-like domain Meth_synt_2 PF01717.13 CAR26154.1 - 5e-143 475.9 0.0 5.6e-139 462.6 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 CAR26154.1 - 3.6e-128 427.2 0.0 9.5e-115 383.1 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain HORMA PF02301.13 CAR26155.1 - 0.069 12.6 0.2 0.084 12.3 0.2 1.1 1 0 0 1 1 1 0 HORMA domain DUF3895 PF13034.1 CAR26155.1 - 0.07 12.6 0.7 0.14 11.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3895) Microtub_assoc PF07989.6 CAR26155.1 - 1.4 8.7 4.5 0.53 10.1 0.4 1.9 2 0 0 2 2 2 0 Microtubule associated RICTOR_N PF14664.1 CAR26156.1 - 2.2e-110 368.7 9.2 6.5e-110 367.2 6.4 1.8 1 1 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 CAR26156.1 - 4.9e-76 254.6 7.9 7.4e-75 250.8 2.0 3.7 3 0 0 3 3 3 2 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 CAR26156.1 - 8.7e-30 103.0 0.3 3e-29 101.3 0.2 2.0 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 CAR26156.1 - 2.1e-28 98.0 0.7 2.1e-27 94.8 0.7 2.6 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, domain 5 IncA PF04156.9 CAR26156.1 - 0.17 11.4 5.4 0.62 9.6 3.7 1.8 1 1 0 1 1 1 0 IncA protein Fib_alpha PF08702.5 CAR26156.1 - 7.4 6.6 11.3 1.5 8.9 4.5 2.4 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Cmc1 PF08583.5 CAR26158.1 - 6.2e-17 61.1 8.3 8.2e-17 60.7 5.7 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like HMG_box_2 PF09011.5 CAR26158.1 - 0.01 16.1 1.6 0.02 15.2 1.1 1.4 1 0 0 1 1 1 0 HMG-box domain CHCH PF06747.8 CAR26158.1 - 0.02 14.7 2.5 0.49 10.3 0.2 2.4 2 0 0 2 2 2 0 CHCH domain DUF4606 PF15379.1 CAR26158.1 - 0.027 14.5 2.6 0.032 14.2 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4606) NDUF_B7 PF05676.8 CAR26158.1 - 0.079 12.3 5.2 0.056 12.8 2.6 1.6 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Proteasome PF00227.21 CAR26159.1 - 3.5e-42 143.8 0.0 4.3e-42 143.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Sec7 PF01369.15 CAR26160.1 - 2.1e-26 92.7 0.5 4.2e-26 91.7 0.3 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 CAR26160.1 - 0.011 15.8 0.1 0.19 11.9 0.1 2.9 3 0 0 3 3 3 0 Pleckstrin homology domain Rad51 PF08423.6 CAR26161.1 - 7.2e-136 451.0 0.0 9.4e-136 450.7 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 CAR26161.1 - 2.8e-14 52.9 0.0 4.2e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 CAR26161.1 - 7.1e-12 45.0 0.0 1e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 CAR26161.1 - 6.9e-11 42.1 0.1 1.5e-10 41.0 0.1 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain KaiC PF06745.8 CAR26161.1 - 2e-06 27.1 0.0 3.2e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 KaiC DnaB_C PF03796.10 CAR26161.1 - 0.026 13.3 0.2 0.077 11.8 0.0 1.8 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_22 PF13401.1 CAR26161.1 - 0.053 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain HHH PF00633.18 CAR26161.1 - 0.074 12.7 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Sel1 PF08238.7 CAR26162.1 - 5.9e-43 144.3 17.2 2.4e-09 37.5 0.8 7.5 7 0 0 7 7 7 7 Sel1 repeat DUF4261 PF14080.1 CAR26162.1 - 0.13 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4261) Kinesin PF00225.18 CAR26163.1 - 4.8e-104 347.6 9.9 6.2e-102 340.7 6.9 2.9 1 1 0 1 1 1 1 Kinesin motor domain Apolipoprotein PF01442.13 CAR26163.1 - 0.0041 16.6 5.7 0.0041 16.6 3.9 4.5 2 1 0 3 3 3 2 Apolipoprotein A1/A4/E domain LEA_6 PF10714.4 CAR26163.1 - 0.076 12.8 0.6 0.23 11.3 0.4 1.8 1 0 0 1 1 1 0 Late embryogenesis abundant protein 18 Carbpep_Y_N PF05388.6 CAR26163.1 - 0.097 12.8 5.1 0.14 12.3 0.1 3.6 3 0 0 3 3 3 0 Carboxypeptidase Y pro-peptide Baculo_PEP_C PF04513.7 CAR26163.1 - 0.22 11.3 20.0 0.14 11.9 1.9 4.4 2 2 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ipi1_N PF12333.3 CAR26163.1 - 9.5 6.2 11.5 0.45 10.5 1.0 3.5 3 1 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation AhpC-TSA PF00578.16 CAR26164.1 - 8.1e-32 109.5 0.0 1.3e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 CAR26164.1 - 4.7e-14 51.7 0.3 9.4e-14 50.7 0.2 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 CAR26164.1 - 5.9e-10 38.8 0.0 9.8e-10 38.1 0.0 1.4 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 CAR26164.1 - 0.037 13.9 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Fungal_trans PF04082.13 CAR26165.1 - 1.8e-25 89.3 1.5 3.5e-25 88.3 1.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR26165.1 - 5.3e-09 35.8 8.7 5.3e-09 35.8 6.0 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UCH PF00443.24 CAR26166.1 - 4.5e-75 252.2 14.6 2.1e-73 246.7 10.1 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CAR26166.1 - 1.1e-26 94.0 4.0 4.5e-20 72.2 0.1 2.8 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Pribosyltran_N PF13793.1 CAR26167.1 - 8.9e-44 147.9 0.3 1.6e-41 140.6 0.0 2.4 2 1 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 CAR26167.1 - 2.5e-34 118.6 1.4 9.5e-29 100.4 0.4 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 CAR26167.1 - 3.8e-13 49.2 0.7 3.5e-12 46.1 0.4 2.3 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CAR26167.1 - 0.0021 17.3 0.1 0.0034 16.6 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase UQ_con PF00179.21 CAR26168.1 - 1.4e-27 95.8 0.1 2e-27 95.3 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CAR26168.1 - 0.014 15.2 0.1 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 RWD domain ADH_zinc_N_2 PF13602.1 CAR26169.1 - 2.7e-12 47.6 0.0 5.9e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CAR26169.1 - 4.9e-06 26.2 0.1 9.6e-06 25.3 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.19 CAR26169.1 - 0.069 13.4 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain zf-CSL PF05207.8 CAR26170.1 - 4.9e-22 77.1 1.7 6.3e-22 76.8 1.2 1.2 1 0 0 1 1 1 1 CSL zinc finger TF_Zn_Ribbon PF08271.7 CAR26170.1 - 0.014 14.7 1.3 0.022 14.0 0.9 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding ATPase-cat_bd PF12156.3 CAR26170.1 - 0.031 14.7 0.0 0.042 14.3 0.0 1.2 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase Ribosomal_S8e PF01201.17 CAR26171.1 - 3.9e-50 169.3 2.2 4.5e-50 169.1 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e AAR2 PF05282.6 CAR26172.1 - 9.1e-48 163.0 0.4 1.1e-47 162.7 0.3 1.1 1 0 0 1 1 1 1 AAR2 protein TINF2_N PF14973.1 CAR26172.1 - 0.14 12.2 0.4 0.27 11.3 0.2 1.4 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus HSP70 PF00012.15 CAR26173.1 - 1.3e-266 885.3 8.9 1.4e-266 885.2 6.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CAR26173.1 - 1.1e-15 57.0 0.4 9.1e-15 54.0 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 CAR26173.1 - 0.026 13.6 4.7 0.076 12.0 0.1 3.0 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase FGGY_C PF02782.11 CAR26173.1 - 0.034 13.7 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain tRNA-synt_1 PF00133.17 CAR26174.1 - 3.2e-239 794.9 0.2 7.6e-239 793.7 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CAR26174.1 - 4e-29 101.3 0.1 1.4e-28 99.5 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CAR26174.1 - 4.7e-20 71.6 1.9 5.5e-07 28.5 0.2 4.3 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 CAR26174.1 - 0.0004 19.6 0.0 0.0013 17.9 0.0 1.9 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.1 CAR26174.1 - 0.0085 15.4 0.1 0.08 12.2 0.0 2.4 2 1 0 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 DUF932 PF06067.6 CAR26175.1 - 0.38 10.0 4.5 0.5 9.6 3.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF932) AAA_23 PF13476.1 CAR26175.1 - 0.69 10.2 4.4 0.75 10.0 3.1 1.1 1 0 0 1 1 1 0 AAA domain PBP_sp32 PF07222.7 CAR26175.1 - 2.8 7.0 8.0 3.7 6.6 5.5 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Atg8 PF02991.11 CAR26176.1 - 1.3e-50 169.6 0.1 1.5e-50 169.4 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 CAR26176.1 - 8.9e-07 29.0 0.0 1.2e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Nucleoporin_C PF03177.9 CAR26177.1 - 1.9e-131 439.4 6.7 2.6e-131 439.0 4.6 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 CAR26177.1 - 5.3e-117 391.1 5.3 5.3e-117 391.1 3.7 1.8 2 0 0 2 2 2 1 Nup133 N terminal like MAM1 PF10434.4 CAR26178.1 - 1.8e-34 119.2 9.2 2.8e-33 115.2 6.4 2.3 1 1 0 1 1 1 1 Monopolin complex protein MAM1 GatB_N PF02934.10 CAR26179.1 - 4.3e-93 311.3 0.1 8.7e-93 310.3 0.0 1.5 2 0 0 2 2 2 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 CAR26179.1 - 7.9e-30 103.5 1.3 1.4e-29 102.7 0.9 1.4 1 0 0 1 1 1 1 GatB domain WD40 PF00400.27 CAR26181.1 - 8e-26 88.9 6.9 2.9e-05 23.7 0.0 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 CAR26181.1 - 9.3e-05 20.7 0.2 0.025 12.7 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 CAR26181.1 - 0.00019 21.2 0.0 0.6 9.7 0.0 3.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A T4-Gluco-transf PF09198.5 CAR26181.1 - 0.14 11.5 0.1 0.27 10.5 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage T4 beta-glucosyltransferase LisH PF08513.6 CAR26182.1 - 1.8e-05 24.3 0.1 3.4e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 LisH ALG3 PF05208.8 CAR26183.1 - 9.8e-122 406.7 23.2 1.2e-121 406.4 16.1 1.0 1 0 0 1 1 1 1 ALG3 protein HEAT_EZ PF13513.1 CAR26184.1 - 3.5e-15 55.9 0.2 0.01 16.2 0.0 8.1 6 1 1 7 7 7 3 HEAT-like repeat IBN_N PF03810.14 CAR26184.1 - 3.8e-11 42.7 7.3 4.5e-08 32.8 0.4 4.9 4 0 0 4 4 4 1 Importin-beta N-terminal domain HEAT PF02985.17 CAR26184.1 - 1.4e-10 40.3 0.2 0.087 12.9 0.0 7.6 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 CAR26184.1 - 2e-10 40.7 3.8 0.04 14.1 0.2 6.5 4 1 2 6 6 6 4 HEAT repeats Ipi1_N PF12333.3 CAR26184.1 - 0.002 18.0 5.7 8 6.4 0.0 6.2 7 0 0 7 7 7 1 Rix1 complex component involved in 60S ribosome maturation Xpo1 PF08389.7 CAR26184.1 - 0.031 14.1 3.4 0.27 11.1 0.1 4.2 5 1 0 5 5 5 0 Exportin 1-like protein Ank PF00023.25 CAR26185.1 - 4e-09 35.8 6.1 0.0016 18.1 0.7 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 CAR26185.1 - 4.2e-09 36.6 2.1 0.0044 17.3 0.4 3.0 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CAR26185.1 - 5.6e-07 29.2 3.5 0.029 14.5 0.2 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CAR26185.1 - 1.7e-06 28.3 6.6 0.0028 18.1 0.3 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CAR26185.1 - 3.2e-06 27.1 6.5 0.0074 16.5 0.6 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.8 CAR26185.1 - 7.1e-06 25.6 0.4 2.8e-05 23.6 0.3 2.0 1 1 0 1 1 1 1 KilA-N domain TMEM247 PF15444.1 CAR26185.1 - 0.017 14.9 1.4 0.042 13.6 0.9 1.6 1 0 0 1 1 1 0 Transmembrane protein 247 Latarcin PF10279.4 CAR26185.1 - 0.9 9.7 8.9 1 9.5 0.2 3.8 3 1 1 4 4 4 0 Latarcin precursor PBP1_TM PF14812.1 CAR26185.1 - 2.3 8.5 14.8 5.2 7.4 4.0 3.8 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LSM PF01423.17 CAR26186.1 - 1.7e-14 53.1 0.4 1.7e-14 53.1 0.3 1.5 2 0 0 2 2 2 1 LSM domain SM-ATX PF14438.1 CAR26186.1 - 0.0009 19.1 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain CAP PF00188.21 CAR26186.1 - 0.79 10.2 7.9 0.95 9.9 4.2 1.8 2 0 0 2 2 2 0 Cysteine-rich secretory protein family EMP70 PF02990.11 CAR26187.1 - 2.7e-121 405.5 12.3 2.7e-121 405.5 8.5 1.4 2 0 0 2 2 2 1 Endomembrane protein 70 MFS_1 PF07690.11 CAR26187.1 - 0.18 10.4 29.9 0.02 13.5 5.9 2.3 1 1 1 2 2 2 0 Major Facilitator Superfamily ODV-E18 PF10717.4 CAR26187.1 - 0.37 10.2 4.4 0.51 9.8 0.3 2.5 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Ni_hydr_CYTB PF01292.15 CAR26187.1 - 7.2 5.9 13.5 0.033 13.5 0.4 2.9 3 1 0 3 3 3 0 Prokaryotic cytochrome b561 TPR_2 PF07719.12 CAR26188.1 - 3.6e-39 129.5 9.0 3e-08 32.9 0.4 8.7 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_1 PF00515.23 CAR26188.1 - 2e-38 128.4 10.0 6.4e-10 38.2 0.6 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.1 CAR26188.1 - 5.1e-36 122.1 15.3 5.1e-13 48.4 0.6 7.0 4 3 4 8 8 8 5 TPR repeat TPR_8 PF13181.1 CAR26188.1 - 2.7e-29 98.7 6.2 4.2e-07 29.2 0.2 8.4 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 CAR26188.1 - 5.7e-23 81.0 3.4 2.6e-08 34.3 0.0 5.9 5 1 0 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 CAR26188.1 - 9.2e-23 80.1 28.1 3.3e-15 55.9 1.5 5.0 5 1 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 CAR26188.1 - 3.5e-22 78.1 12.8 1.1e-06 28.4 0.1 7.2 6 2 1 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 CAR26188.1 - 4.4e-19 67.0 13.5 1.8e-05 24.5 0.2 9.0 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.1 CAR26188.1 - 1e-17 62.4 7.8 1.6e-05 24.3 0.0 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 CAR26188.1 - 2.2e-14 53.5 4.1 1.5e-05 25.2 0.0 5.9 7 1 1 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 CAR26188.1 - 6.7e-14 51.1 0.3 0.055 14.1 0.0 7.5 4 2 4 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.1 CAR26188.1 - 8e-10 38.4 1.0 0.0028 17.4 0.2 4.6 3 2 2 5 5 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 CAR26188.1 - 2.4e-08 33.9 16.1 0.0069 16.7 0.1 8.7 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_10 PF13374.1 CAR26188.1 - 1.4e-06 28.0 2.9 0.031 14.2 0.0 4.4 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 CAR26188.1 - 1.4e-06 27.5 0.0 0.02 13.9 0.0 3.9 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.1 CAR26188.1 - 0.00057 19.9 0.0 9.1 6.4 0.0 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.15 CAR26188.1 - 0.0018 18.1 0.4 5.3 7.2 0.3 3.3 3 0 0 3 3 2 2 PPR repeat Sel1 PF08238.7 CAR26188.1 - 0.0042 17.6 9.4 5.9 7.6 0.0 4.7 5 0 0 5 5 5 1 Sel1 repeat ChAPs PF09295.5 CAR26188.1 - 0.012 14.3 0.1 0.29 9.8 0.0 2.8 2 1 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) SR-25 PF10500.4 CAR26188.1 - 0.048 13.1 9.7 0.1 12.0 6.8 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Fis1_TPR_C PF14853.1 CAR26188.1 - 5 7.0 10.3 1.3 8.9 0.1 4.6 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat SH3_1 PF00018.23 CAR26189.1 - 3.3e-14 51.9 0.2 6.8e-14 50.9 0.1 1.6 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 CAR26189.1 - 1.7e-13 50.6 0.0 4.9e-13 49.1 0.0 1.8 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.12 CAR26189.1 - 6.1e-10 38.8 0.0 1.2e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.1 CAR26189.1 - 1.7e-09 37.1 0.1 3.4e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.1 CAR26189.1 - 2.1e-08 34.4 0.0 9.4e-08 32.3 0.0 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain SH3_2 PF07653.12 CAR26189.1 - 1.2e-05 24.6 0.0 3.9e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain PH_8 PF15409.1 CAR26189.1 - 0.00011 22.2 0.0 0.011 15.7 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain SAM_1 PF00536.25 CAR26189.1 - 0.0003 20.8 0.0 0.00054 20.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Myf5 PF12232.3 CAR26190.1 - 0.039 14.5 1.1 0.32 11.6 0.1 2.6 2 0 0 2 2 2 0 Myogenic determination factor 5 NT-C2 PF10358.4 CAR26191.1 - 1.1e-49 167.6 1.8 3.6e-49 165.9 0.8 2.0 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins zf-C3HC4 PF00097.20 CAR26193.1 - 3.9e-10 39.2 8.0 6.9e-10 38.4 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CAR26193.1 - 8.6e-10 38.1 7.8 1.3e-09 37.5 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CAR26193.1 - 4.1e-09 36.1 9.5 6.4e-09 35.4 6.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CAR26193.1 - 7.1e-09 35.2 8.9 1.2e-08 34.5 6.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CAR26193.1 - 8.9e-08 32.0 8.7 1.7e-07 31.1 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CAR26193.1 - 1.8e-06 27.5 6.0 1.8e-06 27.5 4.2 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CAR26193.1 - 0.0002 21.1 8.4 0.00038 20.2 5.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 CAR26193.1 - 0.0012 18.6 3.1 0.0018 18.0 2.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 CAR26193.1 - 0.0055 16.2 4.5 0.015 14.8 3.2 1.8 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 CAR26193.1 - 0.067 13.3 5.8 0.19 11.8 4.0 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger zf-MIZ PF02891.15 CAR26193.1 - 0.53 9.8 7.5 1.4 8.4 5.2 1.7 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger PRP21_like_P PF12230.3 CAR26193.1 - 0.56 9.6 6.9 0.75 9.2 4.8 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein zf-RING_6 PF14835.1 CAR26193.1 - 1.5 8.6 6.3 21 4.9 4.5 2.3 1 1 1 2 2 2 0 zf-RING of BARD1-type protein FYVE PF01363.16 CAR26193.1 - 4.1 7.3 8.8 29 4.6 6.1 2.3 1 1 0 1 1 1 0 FYVE zinc finger Nop14 PF04147.7 CAR26193.1 - 9.8 3.9 12.4 11 3.7 8.6 1.0 1 0 0 1 1 1 0 Nop14-like family Ribosomal_L14 PF00238.14 CAR26194.1 - 2.7e-31 107.8 0.0 3e-31 107.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e PI3_PI4_kinase PF00454.22 CAR26195.1 - 2.9e-48 164.3 0.5 8.2e-48 162.9 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 CAR26195.1 - 5.7e-22 78.1 4.8 1.1e-21 77.1 1.2 2.9 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 CAR26195.1 - 9.8e-14 50.5 0.1 2.6e-13 49.1 0.1 1.8 1 0 0 1 1 1 1 FATC domain VIT1 PF01988.14 CAR26195.1 - 0.15 11.5 0.3 0.29 10.5 0.2 1.4 1 0 0 1 1 1 0 VIT family SH3_9 PF14604.1 CAR26196.1 - 3.2e-11 42.6 0.1 5.5e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CAR26196.1 - 9e-11 40.9 0.1 1.6e-10 40.1 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CAR26196.1 - 6.4e-08 31.9 0.0 1.2e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain zf-DHHC PF01529.15 CAR26196.1 - 5.3 6.4 9.0 1.2 8.4 2.6 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase Aa_trans PF01490.13 CAR26197.1 - 6.6e-101 337.7 21.4 7.7e-101 337.5 14.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CAR26197.1 - 1e-09 37.7 10.9 1e-09 37.7 7.5 1.7 3 0 0 3 3 3 1 Tryptophan/tyrosine permease family Abhydrolase_9_N PF15420.1 CAR26197.1 - 0.076 12.7 6.1 12 5.6 0.1 3.9 3 1 1 4 4 4 0 Alpha/beta-hydrolase family N-terminus Ribosomal_S21 PF01165.15 CAR26198.1 - 5.1e-12 45.0 0.3 9.3e-12 44.2 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S21 Peptidase_M24 PF00557.19 CAR26199.1 - 8.3e-49 165.9 0.0 1.1e-48 165.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Motile_Sperm PF00635.21 CAR26200.1 - 1.4e-24 85.8 0.0 2.1e-24 85.2 0.0 1.3 1 1 0 1 1 1 1 MSP (Major sperm protein) domain Ribosomal_L32e PF01655.13 CAR26201.1 - 9.1e-44 148.0 1.1 1.1e-43 147.7 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Phospho_p8 PF10195.4 CAR26201.1 - 0.075 12.9 0.6 2 8.3 0.0 2.3 2 0 0 2 2 2 0 DNA-binding nuclear phosphoprotein p8 Asn_synthase PF00733.16 CAR26202.1 - 5.7e-68 229.1 0.0 8.2e-68 228.6 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 CAR26202.1 - 3.7e-34 117.1 0.0 6.1e-34 116.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 CAR26202.1 - 8.8e-28 96.9 0.0 4.2e-27 94.7 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 CAR26202.1 - 1.6e-05 24.2 0.0 2.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 CAR26202.1 - 0.0011 17.7 0.0 0.78 8.3 0.0 2.9 1 1 2 3 3 3 2 Glutamine amidotransferases class-II NAD_synthase PF02540.12 CAR26202.1 - 0.025 13.4 0.0 0.04 12.8 0.0 1.3 1 0 0 1 1 1 0 NAD synthase CBF PF03914.12 CAR26203.1 - 4.9e-45 152.9 0.1 1.3e-44 151.5 0.1 1.8 2 0 0 2 2 2 1 CBF/Mak21 family Metallophos PF00149.23 CAR26204.1 - 2.9e-36 124.7 0.1 5.4e-36 123.8 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 CAR26204.1 - 8e-22 76.6 1.7 6.2e-16 57.7 0.4 3.0 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 CAR26204.1 - 2e-14 52.4 4.7 1.5e-05 24.3 0.1 4.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 CAR26204.1 - 7.6e-14 50.4 0.3 0.0014 18.4 0.0 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat PPP5 PF08321.7 CAR26204.1 - 3.1e-10 39.9 0.3 4.8e-08 32.9 0.0 2.9 2 1 0 2 2 2 1 PPP5 TPR repeat region TPR_17 PF13431.1 CAR26204.1 - 2e-06 27.5 0.9 0.18 12.0 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 CAR26204.1 - 4.9e-05 23.0 0.0 0.00011 21.9 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 CAR26204.1 - 0.00045 20.7 0.0 0.18 12.5 0.0 2.6 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CAR26204.1 - 0.0012 18.4 2.4 13 5.8 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 CAR26204.1 - 0.0021 17.9 2.3 0.25 11.3 0.1 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 CAR26204.1 - 0.014 15.7 0.4 0.61 10.4 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CAR26204.1 - 0.026 14.3 0.3 0.98 9.3 0.1 2.7 2 1 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.1 CAR26204.1 - 0.031 14.0 0.1 0.93 9.4 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.1 CAR26204.1 - 0.08 11.9 0.2 0.19 10.7 0.1 1.4 1 1 0 1 1 1 0 Tetratricopeptide repeat Rrp15p PF07890.7 CAR26205.1 - 9.5e-30 103.3 11.3 9.5e-30 103.3 7.8 2.5 2 1 0 2 2 2 1 Rrp15p DUF2228 PF10228.4 CAR26205.1 - 0.24 10.9 3.1 0.38 10.2 2.1 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) Daxx PF03344.10 CAR26205.1 - 0.42 9.0 29.1 0.52 8.7 20.1 1.1 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 CAR26205.1 - 1.2 8.3 33.6 1.7 7.8 23.3 1.3 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 CAR26205.1 - 4.3 5.2 22.6 7.5 4.4 15.7 1.4 1 0 0 1 1 1 0 CDC45-like protein Kinesin PF00225.18 CAR26206.1 - 4.3e-103 344.5 4.0 4.3e-103 344.5 2.8 2.7 3 1 0 3 3 3 1 Kinesin motor domain HrpB7 PF09486.5 CAR26206.1 - 0.0003 20.7 2.6 0.0003 20.7 1.8 3.6 2 1 1 4 4 4 1 Bacterial type III secretion protein (HrpB7) Fez1 PF06818.10 CAR26206.1 - 0.0024 17.9 3.5 0.0024 17.9 2.4 3.1 3 0 0 3 3 3 2 Fez1 DUF1664 PF07889.7 CAR26206.1 - 0.0032 17.2 6.6 0.0032 17.2 4.6 3.3 4 0 0 4 4 4 1 Protein of unknown function (DUF1664) Filament PF00038.16 CAR26206.1 - 0.0069 15.8 8.7 0.0069 15.8 6.0 3.6 1 1 1 3 3 3 3 Intermediate filament protein DegT_DnrJ_EryC1 PF01041.12 CAR26206.1 - 1.4 7.9 5.9 0.2 10.6 1.0 1.8 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Acyltransferase PF01553.16 CAR26207.1 - 1.9e-13 50.0 0.0 4.5e-13 48.7 0.0 1.5 1 1 0 1 1 1 1 Acyltransferase Acyltransferase PF01553.16 CAR26208.1 - 0.069 12.5 0.0 0.19 11.1 0.0 1.7 1 1 0 1 1 1 0 Acyltransferase Ammonium_transp PF00909.16 CAR26210.1 - 2.4e-117 391.8 24.7 2.7e-117 391.6 17.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family ABC2_membrane_2 PF12679.2 CAR26210.1 - 8.9 5.0 12.1 0.079 11.7 2.5 1.8 2 1 1 3 3 3 0 ABC-2 family transporter protein WD40 PF00400.27 CAR26211.1 - 2.3e-21 74.7 5.4 1.6e-06 27.7 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF3639 PF12341.3 CAR26212.1 - 6.9e-12 45.1 0.7 1.2e-11 44.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3639) RAB3GAP2_N PF14655.1 CAR26212.1 - 0.024 13.6 0.0 0.053 12.5 0.0 1.5 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Cathelicidins PF00666.12 CAR26212.1 - 0.026 14.6 0.0 0.072 13.2 0.0 1.8 1 0 0 1 1 1 0 Cathelicidin DNA_gyraseA_C PF03989.8 CAR26212.1 - 0.075 12.3 0.2 0.26 10.6 0.0 2.0 2 0 0 2 2 2 0 DNA gyrase C-terminal domain, beta-propeller COG2 PF06148.6 CAR26213.1 - 1.9e-08 34.2 3.3 1.9e-08 34.2 2.3 1.8 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 LOH1CR12 PF10158.4 CAR26213.1 - 0.02 14.6 1.5 0.03 14.1 0.4 1.8 2 1 0 2 2 2 0 Tumour suppressor protein Syntaxin PF00804.20 CAR26213.1 - 0.021 14.9 0.4 0.68 10.1 0.3 2.5 1 1 0 1 1 1 0 Syntaxin IncA PF04156.9 CAR26213.1 - 1.2 8.7 10.9 3.3 7.2 3.1 2.4 2 1 0 2 2 2 0 IncA protein Nup54 PF13874.1 CAR26214.1 - 5.8e-42 142.6 3.4 5.8e-42 142.6 2.4 2.6 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 CAR26214.1 - 3.3e-17 62.7 109.7 8.8e-13 48.4 27.5 3.8 1 1 2 3 3 3 3 Nucleoporin FG repeat region DUF605 PF04652.11 CAR26214.1 - 1 8.6 30.1 1.6 8.0 20.9 1.3 1 0 0 1 1 1 0 Vta1 like Ndc1_Nup PF09531.5 CAR26214.1 - 2.1 6.6 11.0 2.5 6.4 7.6 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pex16 PF08610.5 CAR26214.1 - 6 5.7 15.2 11 4.8 10.5 1.4 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) PAT1 PF09770.4 CAR26214.1 - 6.7 4.8 59.5 10 4.2 41.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SprA-related PF12118.3 CAR26214.1 - 9.5 5.4 37.0 0.18 11.0 20.3 1.9 2 0 0 2 2 2 0 SprA-related family Tom5 PF10642.4 CAR26216.1 - 6.1e-23 80.2 0.2 6.4e-23 80.1 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Med26 PF08711.6 CAR26217.1 - 4e-14 51.8 0.0 8.4e-14 50.8 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Med3 PF11593.3 CAR26217.1 - 0.041 13.1 8.3 0.5 9.5 0.5 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal SRP54 PF00448.17 CAR26217.1 - 0.17 11.3 2.0 0.39 10.1 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF4083 PF13314.1 CAR26217.1 - 4.6 7.1 6.3 2 8.3 0.6 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4083) DUF2058 PF09831.4 CAR26217.1 - 6.3 6.6 18.2 0.4 10.5 5.5 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) Ribosom_S12_S23 PF00164.20 CAR26218.1 - 2.2e-40 136.8 0.6 2.6e-40 136.6 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 WD40 PF00400.27 CAR26220.1 - 0.0042 16.9 0.5 6.6 6.7 0.0 4.2 5 0 0 5 5 5 2 WD domain, G-beta repeat LisH PF08513.6 CAR26220.1 - 0.0053 16.4 0.1 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 LisH Acetyltransf_1 PF00583.19 CAR26221.1 - 1.6e-11 44.1 0.0 2.5e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CAR26221.1 - 1.7e-06 27.6 0.0 2.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 CAR26221.1 - 0.0011 19.0 0.0 0.0015 18.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CAR26221.1 - 0.0042 17.2 0.0 0.0061 16.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CAR26221.1 - 0.0057 16.5 0.0 0.0075 16.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CAR26221.1 - 0.081 12.7 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain LSM14 PF12701.2 CAR26222.1 - 3.3e-22 78.1 1.3 6.7e-22 77.1 0.0 2.1 2 0 0 2 2 2 1 Scd6-like Sm domain FDF PF09532.5 CAR26222.1 - 4.9e-06 27.0 16.1 3.4e-05 24.3 0.4 3.4 2 1 1 3 3 3 2 FDF domain TFIIA PF03153.8 CAR26222.1 - 0.099 12.5 17.9 0.13 12.0 12.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BAF1_ABF1 PF04684.8 CAR26222.1 - 0.13 11.0 3.4 0.19 10.5 2.3 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SM-ATX PF14438.1 CAR26222.1 - 0.2 11.6 0.0 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 Ataxin 2 SM domain Dicty_REP PF05086.7 CAR26222.1 - 2.6 5.6 5.3 3.1 5.4 3.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein GRP PF07172.6 CAR26222.1 - 2.8 8.4 15.8 0.16 12.4 6.7 2.0 2 0 0 2 2 2 0 Glycine rich protein family DDHD PF02862.12 CAR26224.1 - 1.1e-46 159.5 0.1 1.7e-29 103.2 0.0 2.4 1 1 1 2 2 2 2 DDHD domain LCAT PF02450.10 CAR26224.1 - 0.00043 19.3 0.0 0.0013 17.7 0.0 1.7 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase DUF2305 PF10230.4 CAR26224.1 - 0.0039 16.6 0.0 0.0067 15.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 CAR26224.1 - 0.025 14.4 0.0 0.066 13.0 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CAR26224.1 - 0.032 14.0 0.0 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF21 PF01595.15 CAR26225.1 - 2.6e-29 101.8 0.8 2.6e-29 101.8 0.6 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF21 CBS PF00571.23 CAR26225.1 - 0.0077 16.0 0.0 1.1 9.1 0.0 2.7 2 0 0 2 2 2 1 CBS domain T4_Gp59_C PF08994.5 CAR26225.1 - 0.087 12.9 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase C-term Zip PF02535.17 CAR26225.1 - 6.9 5.5 15.5 0.22 10.4 2.2 3.0 3 1 0 3 3 3 0 ZIP Zinc transporter Pkinase PF00069.20 CAR26226.1 - 4.8e-57 193.0 0.0 1.2e-56 191.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR26226.1 - 3.8e-22 78.6 0.0 6.4e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR26226.1 - 0.0004 19.4 0.0 0.0032 16.4 0.0 2.3 2 0 0 2 2 2 1 Kinase-like NCD2 PF04905.8 CAR26226.1 - 8 6.2 9.8 0.36 10.6 1.4 2.6 2 1 0 2 2 2 0 NAB conserved region 2 (NCD2) Pribosyl_synth PF14572.1 CAR26227.1 - 2.1e-44 151.4 0.3 3.5e-44 150.7 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 CAR26227.1 - 5.2e-36 122.8 0.1 3.1e-35 120.3 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 CAR26227.1 - 2.9e-14 52.8 0.0 4.3e-13 49.0 0.0 2.4 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CAR26227.1 - 0.039 13.1 0.1 0.068 12.3 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Adap_comp_sub PF00928.16 CAR26228.1 - 8.3e-77 257.8 0.1 1.1e-76 257.4 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family CRT10 PF08728.5 CAR26230.1 - 6.7e-154 513.6 0.0 9.6e-154 513.1 0.0 1.2 1 0 0 1 1 1 1 CRT10 Pkinase PF00069.20 CAR26231.1 - 2.2e-50 171.2 0.0 4.4e-50 170.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR26231.1 - 2.7e-22 79.0 0.0 7.5e-22 77.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR26231.1 - 0.00068 18.6 0.0 0.0035 16.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CAR26231.1 - 0.00087 19.0 0.0 0.7 9.5 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Actin PF00022.14 CAR26232.1 - 6.9e-114 380.3 0.0 8.2e-114 380.0 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CAR26232.1 - 0.0056 15.3 0.0 0.032 12.8 0.0 2.1 1 1 0 1 1 1 1 MreB/Mbl protein DUF3449 PF11931.3 CAR26233.1 - 1.1e-64 217.5 0.1 1.1e-64 217.5 0.1 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) zf-C2H2_jaz PF12171.3 CAR26233.1 - 4.9e-09 36.0 1.6 3.4e-08 33.3 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CAR26233.1 - 6.5e-08 32.5 3.1 6.8e-06 26.0 0.5 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CAR26233.1 - 0.0004 20.4 1.0 0.015 15.3 0.1 2.7 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 CAR26233.1 - 0.012 15.8 6.6 0.13 12.6 0.5 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Gon7 PF08738.5 CAR26233.1 - 0.037 14.0 0.2 0.13 12.2 0.1 2.0 1 0 0 1 1 1 0 Gon7 family PAP1 PF08601.5 CAR26233.1 - 0.038 13.6 0.8 0.063 12.9 0.6 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 AKAP95 PF04988.7 CAR26233.1 - 0.057 13.2 4.3 0.88 9.3 0.0 2.9 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2 PF00096.21 CAR26233.1 - 0.079 13.3 6.3 2 8.8 0.4 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type IncA PF04156.9 CAR26233.1 - 5.7 6.4 6.3 0.63 9.6 1.1 1.7 2 0 0 2 2 2 0 IncA protein DEAD PF00270.24 CAR26234.1 - 7.1e-47 159.0 0.0 2.6e-45 153.9 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR26234.1 - 5.8e-22 77.3 0.2 2.6e-21 75.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 CAR26234.1 - 1.3e-20 72.9 6.3 1.2e-19 69.8 4.4 2.9 1 0 0 1 1 1 1 DBP10CT (NUC160) domain T4-Gluco-transf PF09198.5 CAR26234.1 - 0.1 11.9 0.1 0.25 10.7 0.1 1.6 1 0 0 1 1 1 0 Bacteriophage T4 beta-glucosyltransferase tRNA_Me_trans PF03054.11 CAR26235.1 - 8.2e-114 379.8 0.0 9.5e-114 379.6 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.16 CAR26235.1 - 3.1e-05 23.6 0.0 4.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.12 CAR26235.1 - 0.029 13.2 0.0 0.078 11.8 0.0 1.6 2 0 0 2 2 2 0 NAD synthase Inositol_P PF00459.20 CAR26236.1 - 9e-57 192.4 0.0 1.6e-56 191.5 0.0 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family Git3 PF11710.3 CAR26237.1 - 2.8e-74 249.0 10.8 4.5e-74 248.3 7.5 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 CAR26237.1 - 7.7e-33 112.1 5.7 7.7e-33 112.1 3.9 2.0 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term RseC_MucC PF04246.7 CAR26237.1 - 0.27 10.7 0.0 0.85 9.1 0.0 1.8 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF2721 PF11026.3 CAR26237.1 - 1.4 8.5 4.8 7.3 6.2 1.9 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) Exo_endo_phos PF03372.18 CAR26238.1 - 4.1e-21 76.0 0.0 5.3e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PseudoU_synth_2 PF00849.17 CAR26239.1 - 3.8e-32 111.3 0.9 5.3e-32 110.9 0.0 1.7 2 0 0 2 2 2 1 RNA pseudouridylate synthase dCMP_cyt_deam_1 PF00383.17 CAR26239.1 - 3.4e-19 68.3 0.0 8.6e-19 67.0 0.0 1.7 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region PQQ PF01011.16 CAR26239.1 - 0.051 13.1 0.1 0.13 11.8 0.1 1.8 1 0 0 1 1 1 0 PQQ enzyme repeat NARP1 PF12569.3 CAR26240.1 - 1.8e-111 373.4 19.4 2.5e-80 270.7 1.4 3.5 3 1 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.12 CAR26240.1 - 5.1e-17 60.3 11.3 0.014 15.2 0.0 9.0 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_16 PF13432.1 CAR26240.1 - 5.6e-15 55.5 7.7 6.3e-05 23.5 0.0 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.1 CAR26240.1 - 1e-13 50.6 8.4 0.0065 16.0 0.1 5.6 5 0 0 5 5 5 3 TPR repeat TPR_14 PF13428.1 CAR26240.1 - 1.7e-13 49.9 0.6 1.5 9.6 0.0 8.6 6 3 4 10 10 9 3 Tetratricopeptide repeat TPR_1 PF00515.23 CAR26240.1 - 1.9e-12 46.1 12.5 0.13 11.9 0.0 8.7 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 CAR26240.1 - 2e-11 44.0 10.4 0.0026 18.0 0.1 6.5 5 3 1 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 CAR26240.1 - 3.6e-11 42.8 16.0 8.3e-06 25.6 0.1 6.6 7 1 0 7 7 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 CAR26240.1 - 2.6e-08 33.4 5.8 0.0041 17.2 0.0 6.9 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 CAR26240.1 - 4.1e-07 29.3 12.9 0.18 11.6 0.1 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 CAR26240.1 - 1.3e-05 24.5 3.8 8.9 6.3 0.0 7.4 7 0 0 7 7 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CAR26240.1 - 9.1e-05 22.2 6.7 0.14 12.0 0.1 4.3 4 0 0 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 CAR26240.1 - 0.0092 16.3 8.4 3.5 8.3 0.0 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_10 PF13374.1 CAR26240.1 - 0.53 10.2 6.7 3.1 7.8 0.0 4.5 7 0 0 7 7 6 0 Tetratricopeptide repeat HLH PF00010.21 CAR26241.1 - 1e-16 60.3 0.1 1.9e-16 59.4 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SIR2 PF02146.12 CAR26242.1 - 4.1e-65 218.8 0.0 6.3e-65 218.2 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 CAR26242.1 - 8.9e-63 210.4 0.4 1.4e-62 209.8 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 CAR26242.1 - 0.00027 20.6 0.0 0.11 12.2 0.0 2.5 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain ECR1_N PF14382.1 CAR26242.1 - 0.08 12.2 0.0 0.41 9.9 0.0 2.1 2 0 0 2 2 2 0 Exosome complex exonuclease RRP4 N-terminal region DUF164 PF02591.10 CAR26242.1 - 0.29 10.9 1.1 0.82 9.5 0.3 2.1 2 0 0 2 2 2 0 Putative zinc ribbon domain zf-met PF12874.2 CAR26243.1 - 8.9e-05 22.5 1.1 0.00018 21.5 0.8 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Nuf2 PF03800.9 CAR26244.1 - 2.2e-45 154.2 0.8 2.2e-45 154.2 0.6 3.1 2 1 3 5 5 5 1 Nuf2 family CENP-F_leu_zip PF10473.4 CAR26244.1 - 0.0091 15.8 10.1 0.0091 15.8 7.0 3.6 1 1 2 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IFT46_B_C PF12317.3 CAR26244.1 - 0.16 11.3 13.3 0.14 11.4 0.4 3.3 2 1 1 3 3 3 0 Intraflagellar transport complex B protein 46 C terminal Mga PF05043.8 CAR26244.1 - 0.62 10.3 10.8 0.27 11.5 1.7 3.0 1 1 0 2 2 2 0 Mga helix-turn-helix domain Rep_fac-A_C PF08646.5 CAR26244.1 - 0.86 9.2 0.0 0.86 9.2 0.0 3.2 3 1 1 4 4 4 0 Replication factor-A C terminal domain Reo_sigmaC PF04582.7 CAR26244.1 - 4.3 6.4 11.9 0.57 9.3 2.7 2.3 1 1 2 3 3 3 0 Reovirus sigma C capsid protein FMO-like PF00743.14 CAR26245.1 - 4.8e-15 54.7 6.4 6.1e-06 24.7 0.5 3.3 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 CAR26245.1 - 1.7e-07 31.5 0.0 0.023 14.7 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CAR26245.1 - 0.00085 19.1 0.0 0.17 11.6 0.0 3.6 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CAR26245.1 - 0.0019 18.0 0.0 1 9.1 0.0 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CAR26245.1 - 0.0026 17.7 0.0 0.0057 16.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CAR26245.1 - 0.059 12.2 0.1 0.16 10.8 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 CAR26245.1 - 0.2 10.1 0.1 0.3 9.4 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein PAPS_reduct PF01507.14 CAR26248.1 - 4.5e-30 104.7 0.0 2.5e-29 102.3 0.0 1.9 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family CHCH PF06747.8 CAR26249.1 - 0.0001 22.1 0.6 0.00014 21.7 0.4 1.2 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 CAR26249.1 - 0.025 14.3 0.8 0.029 14.1 0.6 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Sdh5 PF03937.11 CAR26250.1 - 4e-26 90.5 0.3 5.7e-26 90.0 0.2 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase E1_DerP2_DerF2 PF02221.10 CAR26251.1 - 4.4e-26 91.7 0.0 5.2e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 ML domain DUF4625 PF15418.1 CAR26251.1 - 0.016 15.3 0.0 0.026 14.6 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4625) TRP_N PF14558.1 CAR26251.1 - 0.037 14.0 0.0 0.045 13.7 0.0 1.2 1 0 0 1 1 1 0 ML-like domain Metallophos PF00149.23 CAR26252.1 - 1.4e-43 148.5 0.1 1.8e-43 148.2 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CAR26252.1 - 0.00033 20.5 0.0 0.00069 19.4 0.0 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DIL PF01843.14 CAR26252.1 - 0.079 12.8 0.1 0.23 11.3 0.0 1.8 2 0 0 2 2 2 0 DIL domain PCI PF01399.22 CAR26253.1 - 2.3e-13 50.3 0.1 5.6e-12 45.8 0.0 2.6 2 0 0 2 2 2 1 PCI domain Smg4_UPF3 PF03467.10 CAR26254.1 - 9.5e-28 97.3 1.2 1.9e-27 96.3 0.6 1.7 1 1 0 1 1 1 1 Smg-4/UPF3 family DUF1965 PF09248.5 CAR26254.1 - 0.063 13.1 0.2 0.17 11.7 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1965) Suf PF05843.9 CAR26254.1 - 3.2 7.3 15.0 0.44 10.2 5.9 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.11 CAR26254.1 - 7 6.4 9.4 29 4.4 5.2 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Mpv17_PMP22 PF04117.7 CAR26255.1 - 4.8e-05 22.9 0.4 0.00015 21.3 0.1 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family LSM PF01423.17 CAR26256.1 - 1.7e-18 65.9 0.0 3e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CAR26256.1 - 0.00062 19.6 0.1 0.00096 19.0 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain PRP38 PF03371.10 CAR26257.1 - 3.3e-45 153.8 0.7 4.1e-45 153.5 0.5 1.0 1 0 0 1 1 1 1 PRP38 family Nucleoplasmin PF03066.10 CAR26257.1 - 0.13 11.8 9.7 0.18 11.2 6.8 1.3 1 0 0 1 1 1 0 Nucleoplasmin ANAPC15 PF15243.1 CAR26257.1 - 1.1 9.3 12.1 2 8.5 8.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Nop14 PF04147.7 CAR26257.1 - 7.5 4.3 10.7 8.2 4.2 7.4 1.1 1 0 0 1 1 1 0 Nop14-like family Prefoldin PF02996.12 CAR26261.1 - 2.3e-32 111.1 0.2 3.2e-32 110.7 0.2 1.2 1 0 0 1 1 1 1 Prefoldin subunit ABC_tran PF00005.22 CAR26262.1 - 4.1e-54 182.5 0.8 4e-26 91.9 0.1 2.9 3 0 0 3 3 3 2 ABC transporter ABC2_membrane PF01061.19 CAR26262.1 - 6.1e-41 139.8 31.0 4.6e-27 94.5 8.6 2.5 2 0 0 2 2 2 2 ABC-2 type transporter AAA_21 PF13304.1 CAR26262.1 - 1.8e-18 67.5 6.7 1.2e-07 31.9 3.0 4.4 3 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 CAR26262.1 - 3.6e-10 39.4 3.4 5.2e-06 25.8 0.1 3.0 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 CAR26262.1 - 1.5e-09 37.2 2.3 0.00013 21.1 0.2 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 CAR26262.1 - 1.5e-09 37.4 0.1 0.0016 17.5 0.0 4.3 4 0 0 4 4 4 2 AAA ATPase domain AAA_25 PF13481.1 CAR26262.1 - 5.9e-08 32.3 0.2 0.00099 18.5 0.0 4.0 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.1 CAR26262.1 - 1.1e-07 32.0 0.1 0.0071 16.3 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 CAR26262.1 - 6.9e-07 30.1 0.0 0.051 14.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CAR26262.1 - 8.6e-07 28.4 1.7 0.043 13.3 0.2 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.7 CAR26262.1 - 8.8e-06 25.4 0.0 0.0069 16.0 0.0 3.4 3 0 0 3 3 3 1 NACHT domain AAA_18 PF13238.1 CAR26262.1 - 9.1e-06 26.0 0.1 0.039 14.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CAR26262.1 - 2.9e-05 24.2 0.2 0.21 11.6 0.0 3.5 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.1 CAR26262.1 - 7.7e-05 23.1 2.1 0.03 14.6 0.1 2.9 2 1 1 3 3 2 1 AAA domain MMR_HSR1 PF01926.18 CAR26262.1 - 0.00012 22.0 0.3 0.28 11.1 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase T2SE PF00437.15 CAR26262.1 - 0.00023 20.1 0.1 0.03 13.2 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.1 CAR26262.1 - 0.00045 19.9 0.1 0.044 13.5 0.0 3.1 3 0 0 3 3 3 1 Part of AAA domain Miro PF08477.8 CAR26262.1 - 0.00047 20.6 0.0 1.9 8.9 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_28 PF13521.1 CAR26262.1 - 0.00047 20.1 0.0 0.059 13.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 CAR26262.1 - 0.00074 19.0 0.6 0.14 11.6 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 CAR26262.1 - 0.00079 19.1 0.0 0.58 9.8 0.0 2.6 2 0 0 2 2 2 1 Archaeal ATPase RNA_helicase PF00910.17 CAR26262.1 - 0.0008 19.5 0.3 0.35 11.0 0.0 2.8 2 0 0 2 2 2 1 RNA helicase SbcCD_C PF13558.1 CAR26262.1 - 0.0013 18.6 0.3 1.5 8.7 0.0 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.13 CAR26262.1 - 0.002 17.6 1.8 0.026 13.9 0.2 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA PF00004.24 CAR26262.1 - 0.0032 17.6 0.1 20 5.4 0.0 3.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 CAR26262.1 - 0.0033 17.1 1.0 1 9.0 0.2 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 CAR26262.1 - 0.0042 16.9 0.0 3.2 7.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CAR26262.1 - 0.0044 16.9 0.0 4.7 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 CAR26262.1 - 0.0051 16.4 0.3 4.9 6.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.17 CAR26262.1 - 0.0055 15.6 0.2 2.6 6.8 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain KAP_NTPase PF07693.9 CAR26262.1 - 0.0059 15.6 0.0 2.2 7.1 0.0 2.4 2 0 0 2 2 2 1 KAP family P-loop domain AAA_30 PF13604.1 CAR26262.1 - 0.01 15.4 0.1 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 CAR26262.1 - 0.029 14.0 0.0 1.8 8.2 0.0 3.1 3 0 0 3 3 3 0 NTPase AAA_10 PF12846.2 CAR26262.1 - 0.03 13.7 9.2 0.44 9.9 0.3 2.3 2 0 0 2 2 2 0 AAA-like domain PduV-EutP PF10662.4 CAR26262.1 - 0.031 13.7 0.4 4 6.9 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Adeno_IVa2 PF02456.10 CAR26262.1 - 0.035 12.7 0.5 0.12 10.9 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein Zeta_toxin PF06414.7 CAR26262.1 - 0.051 12.6 0.0 4.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin PRK PF00485.13 CAR26262.1 - 0.091 12.3 0.3 4.6 6.7 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF87 PF01935.12 CAR26262.1 - 0.13 12.0 6.4 2 8.1 0.5 3.3 3 1 1 4 4 3 0 Domain of unknown function DUF87 DUF2791 PF10923.3 CAR26262.1 - 0.13 10.8 0.0 4.9 5.6 0.0 2.3 2 0 0 2 2 2 0 P-loop Domain of unknown function (DUF2791) ATP_bind_1 PF03029.12 CAR26262.1 - 0.15 11.5 1.2 5.5 6.4 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Pox_A32 PF04665.7 CAR26262.1 - 0.16 11.1 3.4 0.25 10.6 0.2 2.7 3 0 0 3 3 2 0 Poxvirus A32 protein KaiC PF06745.8 CAR26262.1 - 0.18 10.9 0.9 1 8.4 0.0 2.7 4 0 0 4 4 3 0 KaiC ABC_ATPase PF09818.4 CAR26262.1 - 0.26 9.8 0.1 0.98 7.9 0.0 1.9 2 0 0 2 2 2 0 Predicted ATPase of the ABC class UPF0079 PF02367.12 CAR26262.1 - 0.28 10.7 3.8 0.58 9.7 0.1 2.6 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 Dynamin_N PF00350.18 CAR26262.1 - 2.7 7.7 7.0 5.4 6.7 0.6 2.6 2 0 0 2 2 2 0 Dynamin family DUF336 PF03928.9 CAR26263.1 - 2.1e-22 79.3 0.0 2.8e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF336) DUF1391 PF07151.7 CAR26263.1 - 0.03 13.7 0.1 0.072 12.5 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1391) NatB_MDM20 PF09797.4 CAR26265.1 - 5.2e-53 180.0 5.8 5.2e-53 180.0 4.1 2.4 3 1 0 3 3 3 1 N-acetyltransferase B complex (NatB) non catalytic subunit Brix PF04427.13 CAR26266.1 - 1.5e-40 138.9 0.9 1.9e-40 138.5 0.6 1.1 1 0 0 1 1 1 1 Brix domain DUF468 PF04318.7 CAR26266.1 - 0.0094 16.4 0.1 0.038 14.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF468) DUF2611 PF11022.3 CAR26267.1 - 5.1e-22 77.7 0.0 5.5e-22 77.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) Peptidase_S10 PF00450.17 CAR26268.1 - 3.8e-125 418.3 0.2 4.7e-125 418.0 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 CAR26268.1 - 8.8e-05 22.4 0.0 0.0013 18.7 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family SIN1 PF05422.7 CAR26269.1 - 2.9e-28 98.6 5.3 6.7e-16 57.8 3.5 3.2 3 0 0 3 3 3 2 Stress-activated map kinase interacting protein 1 (SIN1) RBD PF02196.10 CAR26269.1 - 0.018 14.7 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 Raf-like Ras-binding domain RNase_T PF00929.19 CAR26270.1 - 4.6e-23 82.3 0.2 4e-22 79.2 0.0 2.0 2 0 0 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.15 CAR26270.1 - 0.0019 17.7 0.0 0.0059 16.0 0.0 1.9 1 1 0 1 1 1 1 3'-5' exonuclease RasGAP PF00616.14 CAR26271.1 - 4.1e-33 114.7 2.2 1.3e-32 113.0 0.1 2.9 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase DUF3321 PF11968.3 CAR26272.1 - 1.6e-82 276.4 0.0 2.3e-82 275.9 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 CAR26272.1 - 1.5e-05 24.7 0.0 3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CAR26272.1 - 0.042 14.3 0.0 0.078 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DEAD PF00270.24 CAR26273.1 - 1.3e-37 128.9 0.1 4.6e-37 127.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR26273.1 - 4.4e-23 80.9 0.2 1.2e-21 76.3 0.1 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Hid1 PF12722.2 CAR26273.1 - 0.24 9.0 10.5 0.43 8.2 7.3 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.17 CAR26273.1 - 0.61 9.0 5.7 1 8.2 4.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Tim54 PF11711.3 CAR26273.1 - 3.6 6.0 20.9 0.21 10.1 10.4 1.9 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 IncA PF04156.9 CAR26273.1 - 4.4 6.8 17.8 0.3 10.6 8.1 2.2 2 0 0 2 2 2 0 IncA protein DUF913 PF06025.7 CAR26273.1 - 4.6 5.8 11.4 13 4.3 7.9 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) eRF1_2 PF03464.10 CAR26274.1 - 7.6e-45 152.5 0.2 1.3e-44 151.7 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 CAR26274.1 - 7.8e-38 129.2 0.3 1.6e-37 128.2 0.2 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 CAR26274.1 - 6.9e-29 100.0 0.0 1.2e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 ATG19_autophagy PF12744.2 CAR26275.1 - 1.1e-11 44.4 0.1 4.7e-10 39.1 0.0 2.2 1 1 1 2 2 2 2 Autophagy protein Atg19, Atg8-binding ZZ PF00569.12 CAR26275.1 - 3.6e-09 35.9 4.0 3.6e-09 35.9 2.8 2.1 2 0 0 2 2 2 1 Zinc finger, ZZ type DUF221 PF02714.10 CAR26276.1 - 7.8e-104 347.0 14.0 7.8e-104 347.0 9.7 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CAR26276.1 - 7.3e-38 129.5 2.2 1.3e-37 128.7 0.8 2.0 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 CAR26276.1 - 2.4e-27 94.6 0.1 4.4e-27 93.7 0.1 1.5 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 CAR26276.1 - 6.2e-16 58.6 2.1 1.1e-15 57.9 1.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) ADH_N PF08240.7 CAR26277.1 - 3e-30 104.2 1.5 7.4e-30 102.9 0.1 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CAR26277.1 - 4.6e-25 87.6 2.3 6.6e-25 87.1 1.6 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CAR26277.1 - 7.4e-05 23.6 0.1 0.00018 22.3 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 CAR26277.1 - 0.037 14.0 1.5 0.054 13.5 1.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding 2-Hacid_dh_C PF02826.14 CAR26277.1 - 0.078 12.1 0.1 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ribosomal_S9 PF00380.14 CAR26278.1 - 1.4e-38 131.8 0.1 2.6e-38 130.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DUF2277 PF10041.4 CAR26278.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2277) DUF3337 PF11816.3 CAR26279.1 - 2.7e-64 217.6 11.1 2.7e-64 217.6 7.7 2.0 2 1 1 3 3 3 1 Domain of unknown function (DUF3337) WD40 PF00400.27 CAR26279.1 - 1.1e-10 40.9 1.9 0.00032 20.4 0.0 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat RNA_pol_Rpb5_N PF03871.9 CAR26280.1 - 2e-33 114.6 0.4 4.2e-33 113.6 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain RNA_pol_Rpb5_C PF01191.14 CAR26280.1 - 2.6e-32 110.2 0.3 4.5e-32 109.4 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain Mrr_cat PF04471.7 CAR26280.1 - 0.072 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Restriction endonuclease RibD_C PF01872.12 CAR26281.1 - 4.2e-35 121.1 0.0 4.8e-35 121.0 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain Pyrid_oxidase_2 PF13883.1 CAR26283.1 - 7e-36 123.5 0.0 8.5e-36 123.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Thioredoxin PF00085.15 CAR26284.1 - 5.4e-10 38.8 0.2 2.2e-09 36.9 0.0 2.0 3 0 0 3 3 3 1 Thioredoxin RGM_C PF06534.8 CAR26284.1 - 0.12 11.5 0.1 0.2 10.8 0.1 1.3 1 0 0 1 1 1 0 Repulsive guidance molecule (RGM) C-terminus Suc_Fer-like PF06999.7 CAR26285.1 - 6.5e-56 189.9 0.0 8.2e-56 189.5 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Aldo_ket_red PF00248.16 CAR26286.1 - 2.4e-39 134.8 0.0 3e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family MutS_V PF00488.16 CAR26287.1 - 5.4e-97 323.8 0.1 9.6e-97 323.0 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CAR26287.1 - 1.2e-33 116.6 1.6 1.2e-33 116.6 1.1 2.0 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.12 CAR26287.1 - 1e-20 74.1 2.0 1.6e-20 73.5 0.1 2.4 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 CAR26287.1 - 2.1e-16 59.8 0.8 7.5e-16 58.0 0.6 2.1 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.15 CAR26287.1 - 1.2e-09 38.1 0.0 8.9e-09 35.3 0.0 2.2 2 0 0 2 2 2 1 MutS domain I HALZ PF02183.13 CAR26288.1 - 9.9e-06 25.1 31.4 0.0084 15.8 0.1 7.1 5 2 2 7 7 7 3 Homeobox associated leucine zipper LPP PF04728.8 CAR26288.1 - 0.0016 18.2 7.4 0.12 12.1 0.1 4.4 3 1 1 4 4 4 1 Lipoprotein leucine-zipper GAS PF13851.1 CAR26288.1 - 0.0023 17.1 10.6 0.0023 17.1 7.3 5.8 4 1 2 6 6 6 3 Growth-arrest specific micro-tubule binding DivIVA PF05103.8 CAR26288.1 - 0.0038 17.2 2.9 0.0038 17.2 2.0 6.7 3 1 5 8 8 8 1 DivIVA protein Tup_N PF08581.5 CAR26288.1 - 0.004 17.3 5.9 0.004 17.3 4.1 5.8 3 1 3 6 6 6 1 Tup N-terminal IncA PF04156.9 CAR26288.1 - 0.19 11.3 53.4 1.4 8.5 8.3 4.6 3 1 1 4 4 4 0 IncA protein CENP-F_leu_zip PF10473.4 CAR26288.1 - 0.21 11.4 63.4 0.097 12.5 9.3 6.2 4 1 2 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HlyD PF00529.15 CAR26288.1 - 3 7.0 11.2 4 6.6 7.0 1.8 1 1 0 1 1 1 0 HlyD family secretion protein PQ-loop PF04193.9 CAR26289.1 - 7e-40 134.3 20.0 4.8e-22 77.2 0.7 3.3 4 0 0 4 4 4 2 PQ loop repeat Steroid_dh PF02544.11 CAR26289.1 - 0.51 10.1 5.1 0.19 11.5 0.7 2.3 2 1 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase DUF2157 PF09925.4 CAR26289.1 - 0.68 9.5 10.4 0.17 11.4 1.6 3.0 3 1 0 3 3 3 0 Predicted membrane protein (DUF2157) tRNA_m1G_MT PF01746.16 CAR26290.1 - 1.8e-39 135.3 0.1 2.9e-39 134.5 0.1 1.4 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Rep_fac_C PF08542.6 CAR26291.1 - 1.3e-14 53.9 0.3 6.3e-14 51.7 0.0 2.2 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 CAR26291.1 - 7.4e-14 51.7 0.1 1.7e-11 44.0 0.1 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 CAR26291.1 - 3.8e-13 49.7 0.0 7.2e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CAR26291.1 - 2.4e-07 30.7 0.0 4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CAR26291.1 - 2.4e-07 30.9 0.1 1.1e-05 25.4 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain Rad17 PF03215.10 CAR26291.1 - 1.2e-06 27.5 0.1 0.00067 18.4 0.0 2.2 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 CAR26291.1 - 5.1e-06 26.6 0.3 0.0014 18.7 0.2 2.6 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.6 CAR26291.1 - 7.6e-06 25.5 0.0 1.9e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.8 CAR26291.1 - 1.5e-05 24.6 0.1 2.9e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Viral_helicase1 PF01443.13 CAR26291.1 - 2.2e-05 24.1 0.0 3.6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.7 CAR26291.1 - 3.3e-05 23.0 0.1 0.00012 21.2 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 CAR26291.1 - 0.0014 17.8 0.1 0.022 13.9 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 CAR26291.1 - 0.0022 17.5 0.1 0.38 10.1 0.0 2.3 1 1 1 2 2 2 1 AAA-like domain NTPase_1 PF03266.10 CAR26291.1 - 0.0045 16.7 0.1 0.072 12.8 0.0 2.3 1 1 0 2 2 2 1 NTPase AAA_19 PF13245.1 CAR26291.1 - 0.0058 16.3 0.0 0.013 15.1 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain ArgK PF03308.11 CAR26291.1 - 0.0099 14.6 0.1 0.1 11.3 0.0 2.3 1 1 1 2 2 2 1 ArgK protein FtsK_SpoIIIE PF01580.13 CAR26291.1 - 0.0099 15.3 0.0 0.024 14.1 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_11 PF13086.1 CAR26291.1 - 0.021 14.4 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CAR26291.1 - 0.065 12.9 0.0 0.17 11.5 0.0 1.8 1 1 0 1 1 1 0 Archaeal ATPase KTI12 PF08433.5 CAR26291.1 - 0.066 12.4 0.0 0.14 11.3 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_18 PF13238.1 CAR26291.1 - 0.11 12.8 0.0 0.27 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Vps52 PF04129.7 CAR26292.1 - 5.6e-127 424.3 20.1 7.2e-127 423.9 13.9 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family CENP-F_leu_zip PF10473.4 CAR26292.1 - 0.0067 16.2 0.5 0.018 14.8 0.4 1.7 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PTS_EIIC PF02378.13 CAR26292.1 - 0.049 12.4 0.0 0.078 11.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase system, EIIC UvrD_C PF13361.1 CAR26293.1 - 5.4e-45 154.3 0.0 1.7e-44 152.7 0.0 1.9 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 CAR26293.1 - 4e-32 111.7 0.1 1.3e-15 57.5 0.0 2.5 1 1 1 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 CAR26293.1 - 7.2e-12 45.3 0.0 3.1e-11 43.3 0.0 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_11 PF13086.1 CAR26293.1 - 3.6e-10 39.8 0.1 1.6e-08 34.4 0.1 2.5 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 CAR26293.1 - 4.3e-10 39.5 0.0 0.00041 19.9 0.0 3.1 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 CAR26293.1 - 5.2e-10 38.9 0.0 1.4e-09 37.5 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 CAR26293.1 - 0.0039 16.7 0.0 0.03 13.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain YL1 PF05764.8 CAR26294.1 - 5.2e-56 189.9 47.0 5.2e-56 189.9 32.6 3.2 2 1 0 3 3 3 1 YL1 nuclear protein YL1_C PF08265.6 CAR26294.1 - 4.5e-11 42.0 0.6 7.4e-11 41.4 0.4 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Methyltransf_23 PF13489.1 CAR26295.1 - 1e-23 83.8 0.0 1.5e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAR26295.1 - 1.4e-17 63.6 0.0 2e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CAR26295.1 - 1.1e-15 57.9 0.0 1.7e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAR26295.1 - 7.1e-15 55.2 0.0 1.3e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR26295.1 - 2.7e-14 53.7 0.0 4.7e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAR26295.1 - 5.8e-10 39.4 0.0 9.5e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CAR26295.1 - 1.2e-07 31.1 0.0 1.9e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 CAR26295.1 - 1.4e-07 30.9 0.0 1.8e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 CAR26295.1 - 1.4e-06 28.2 0.1 5.1e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CAR26295.1 - 3.3e-06 26.5 0.0 5.9e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.6 CAR26295.1 - 2.8e-05 23.6 0.0 0.00012 21.5 0.0 1.8 2 0 0 2 2 2 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.13 CAR26295.1 - 3.3e-05 23.1 0.0 4.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 CAR26295.1 - 0.00082 19.0 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 CAR26295.1 - 0.0015 17.5 0.0 0.0024 16.8 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase PCMT PF01135.14 CAR26295.1 - 0.0031 17.0 0.0 0.005 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 CAR26295.1 - 0.0038 16.3 0.0 1.6 7.7 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase MetW PF07021.7 CAR26295.1 - 0.01 15.1 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.10 CAR26295.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase RrnaAD PF00398.15 CAR26295.1 - 0.022 13.8 0.0 0.041 12.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FtsJ PF01728.14 CAR26295.1 - 0.07 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Snf7 PF03357.16 CAR26296.1 - 1.1e-40 138.7 16.0 1.4e-40 138.4 11.1 1.1 1 0 0 1 1 1 1 Snf7 YlqD PF11068.3 CAR26296.1 - 0.00088 19.3 11.8 0.00088 19.3 8.2 2.2 1 1 1 2 2 2 1 YlqD protein Cep57_MT_bd PF06657.8 CAR26296.1 - 0.001 18.9 6.1 0.001 18.9 4.2 2.6 2 1 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 Fmp27_WPPW PF10359.4 CAR26296.1 - 0.0073 14.7 10.6 0.0082 14.6 6.8 1.4 1 1 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Glutaredoxin PF00462.19 CAR26296.1 - 0.035 14.0 1.7 3.9 7.5 0.1 2.7 1 1 1 2 2 2 0 Glutaredoxin DUF1732 PF08340.6 CAR26296.1 - 0.04 13.7 2.9 0.062 13.1 0.9 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1732) CENP-F_leu_zip PF10473.4 CAR26296.1 - 0.081 12.7 15.9 0.1 12.4 0.4 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Methyltrn_RNA_4 PF09936.4 CAR26296.1 - 0.14 11.6 0.7 0.23 10.9 0.5 1.4 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase PhoU PF01895.14 CAR26296.1 - 0.16 12.4 0.2 0.16 12.4 0.1 2.5 2 1 0 2 2 2 0 PhoU domain Prefoldin PF02996.12 CAR26296.1 - 0.18 11.4 0.1 0.18 11.4 0.1 3.5 2 1 2 4 4 4 0 Prefoldin subunit Mnd1 PF03962.10 CAR26296.1 - 0.34 10.5 14.8 0.52 9.9 7.2 2.1 1 1 1 2 2 2 0 Mnd1 family Exonuc_VII_L PF02601.10 CAR26296.1 - 0.48 9.5 12.4 0.59 9.2 8.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.14 CAR26296.1 - 0.64 7.8 7.3 0.87 7.3 5.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIVA PF05103.8 CAR26296.1 - 1.1 9.2 14.3 3.9 7.5 4.8 2.5 1 1 1 2 2 2 0 DivIVA protein Tropomyosin_1 PF12718.2 CAR26296.1 - 1.2 8.9 15.4 0.38 10.5 7.8 2.0 1 1 1 2 2 2 0 Tropomyosin like UPF0242 PF06785.6 CAR26296.1 - 1.3 7.5 8.7 2.1 6.9 6.1 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) FlaC_arch PF05377.6 CAR26296.1 - 1.5 8.7 6.0 7.4 6.5 0.0 3.4 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Peptidase_S46 PF10459.4 CAR26296.1 - 1.9 6.8 12.8 2.3 6.5 8.9 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF2730 PF10805.3 CAR26296.1 - 2 8.1 6.6 10 5.9 2.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) DUF972 PF06156.8 CAR26296.1 - 2.6 8.4 13.6 41 4.5 0.6 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) FliJ PF02050.11 CAR26296.1 - 3.7 7.6 23.8 2.2 8.3 3.3 2.9 1 1 2 3 3 3 0 Flagellar FliJ protein Serine_rich PF08824.5 CAR26296.1 - 5.3 6.7 18.9 6.3 6.4 7.3 2.8 1 1 2 3 3 3 0 Serine rich protein interaction domain DASH_Dam1 PF08653.5 CAR26296.1 - 5.6 6.8 8.8 9.1 6.1 0.3 3.3 3 0 0 3 3 3 0 DASH complex subunit Dam1 Syntaxin-6_N PF09177.6 CAR26296.1 - 5.8 7.4 10.3 1.4 9.3 2.0 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal COG2 PF06148.6 CAR26296.1 - 6.8 6.5 10.5 4.8 7.0 2.2 2.8 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 IncA PF04156.9 CAR26296.1 - 7.8 6.0 23.1 1.3e+03 -1.3 16.0 2.6 1 1 0 1 1 1 0 IncA protein DUF342 PF03961.8 CAR26296.1 - 8.3 4.7 11.0 12 4.1 6.1 1.9 1 1 2 3 3 3 0 Protein of unknown function (DUF342) CorA PF01544.13 CAR26296.1 - 10 5.0 12.1 24 3.8 7.4 1.9 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein tRNA-synt_1b PF00579.20 CAR26297.1 - 5.9e-18 65.0 0.0 4.4e-17 62.1 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) DHBP_synthase PF00926.14 CAR26298.1 - 5.1e-80 267.2 0.0 5.9e-80 267.0 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase WD40 PF00400.27 CAR26299.1 - 3.1e-05 23.6 5.5 0.0028 17.4 1.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat Sld5 PF05916.6 CAR26300.1 - 9.7e-19 67.6 0.9 1.8e-18 66.7 0.6 1.5 1 0 0 1 1 1 1 GINS complex protein IL31 PF15209.1 CAR26300.1 - 0.033 13.7 0.1 0.068 12.7 0.1 1.5 1 0 0 1 1 1 0 Interleukin 31 Peptidase_M16_C PF05193.16 CAR26301.1 - 1.1e-14 54.5 0.0 8.8e-11 41.8 0.0 3.3 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CAR26301.1 - 1.4e-09 37.8 0.0 4.7e-08 32.9 0.0 2.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Pkinase PF00069.20 CAR26302.1 - 1e-62 211.6 0.1 2.6e-62 210.3 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR26302.1 - 5.2e-34 117.4 0.0 7.7e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR26302.1 - 5.7e-11 41.9 0.0 1e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CAR26302.1 - 0.00051 19.1 0.0 0.0012 17.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CAR26302.1 - 0.036 13.3 0.3 0.13 11.6 0.2 1.8 1 1 0 1 1 1 0 RIO1 family APH PF01636.18 CAR26302.1 - 0.054 13.2 0.0 0.093 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family HlyIII PF03006.15 CAR26304.1 - 2.5e-53 180.7 20.1 3e-53 180.5 14.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF4401 PF14351.1 CAR26304.1 - 0.0014 17.6 6.3 0.0023 16.9 4.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) DUF998 PF06197.8 CAR26304.1 - 1 8.6 12.6 0.021 14.1 1.3 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF998) PTS_2-RNA PF01885.11 CAR26306.1 - 2.1e-55 186.9 0.3 2.8e-55 186.5 0.2 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family La PF05383.12 CAR26306.1 - 0.0048 16.6 0.0 0.0099 15.6 0.0 1.6 1 0 0 1 1 1 1 La domain CPL PF08144.6 CAR26309.1 - 2.9e-20 72.6 0.0 1e-19 70.8 0.0 2.0 1 0 0 1 1 1 1 CPL (NUC119) domain PUF PF00806.14 CAR26309.1 - 0.015 14.7 1.3 10 5.8 0.0 5.0 6 0 0 6 6 6 0 Pumilio-family RNA binding repeat DUF2890 PF11081.3 CAR26309.1 - 0.21 11.6 8.2 0.42 10.6 5.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Sugar_tr PF00083.19 CAR26310.1 - 2.1e-136 455.1 25.9 2.5e-136 454.8 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR26310.1 - 1.4e-33 116.1 29.0 1.1e-30 106.5 14.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CAR26310.1 - 4.5e-07 28.4 3.0 4.5e-07 28.4 2.1 2.3 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 CAR26310.1 - 0.00028 19.1 1.3 0.00028 19.1 0.9 1.9 2 0 0 2 2 2 1 Transmembrane secretion effector DUF1673 PF07895.6 CAR26310.1 - 0.71 9.3 7.3 0.095 12.2 2.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) PsbX PF06596.6 CAR26310.1 - 9.3 6.0 10.6 0.19 11.4 0.4 3.3 3 0 0 3 3 3 0 Photosystem II reaction centre X protein (PsbX) Sec20 PF03908.8 CAR26311.1 - 8.6e-28 95.8 0.9 8.6e-28 95.8 0.7 3.0 4 0 0 4 4 4 1 Sec20 TMEM240 PF15207.1 CAR26311.1 - 0.13 11.8 0.5 0.27 10.8 0.4 1.5 1 0 0 1 1 1 0 TMEM240 family ERG4_ERG24 PF01222.12 CAR26313.1 - 7.1e-162 538.8 8.1 8e-162 538.6 5.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 CAR26313.1 - 0.002 17.4 0.4 0.002 17.4 0.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) DDE_Tnp_Tn3 PF01526.12 CAR26313.1 - 0.0066 15.1 0.0 0.0094 14.6 0.0 1.1 1 0 0 1 1 1 1 Tn3 transposase DDE domain Aha1_N PF09229.6 CAR26314.1 - 1.5e-29 102.5 0.0 1.9e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal RNase_P_pop3 PF08228.6 CAR26315.1 - 1e-40 139.1 0.9 1.3e-40 138.8 0.6 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 WSC PF01822.14 CAR26316.1 - 4e-13 49.0 9.4 1.5e-12 47.2 6.5 2.0 1 0 0 1 1 1 1 WSC domain SKG6 PF08693.5 CAR26316.1 - 0.058 12.7 7.5 0.13 11.5 5.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Ribosomal_L18e PF00828.14 CAR26317.1 - 8.3e-24 84.4 1.1 4.5e-23 82.0 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 DUF1751 PF08551.5 CAR26318.1 - 4.5e-28 97.4 3.0 4.5e-28 97.4 2.1 1.9 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) HLH PF00010.21 CAR26319.1 - 0.0046 16.6 1.1 0.0046 16.6 0.7 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain RRM_1 PF00076.17 CAR26320.1 - 2e-18 65.7 0.6 4.6e-10 38.9 0.1 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR26320.1 - 1.3e-13 50.5 0.6 2.8e-06 27.0 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR26320.1 - 3.9e-13 49.1 0.1 2e-07 30.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CAR26320.1 - 0.031 14.0 0.6 0.12 12.1 0.1 2.0 2 0 0 2 2 2 0 Limkain b1 Adaptin_N PF01602.15 CAR26321.1 - 3.9e-113 378.5 11.5 4.9e-113 378.2 8.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 CAR26321.1 - 1.4e-47 161.2 2.9 1.4e-47 161.2 0.7 2.0 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 CAR26321.1 - 8.9e-12 45.1 2.1 0.00054 20.1 0.1 5.5 3 2 1 4 4 4 3 HEAT repeats HEAT PF02985.17 CAR26321.1 - 0.00039 20.2 5.3 8.3 6.7 0.0 6.3 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.1 CAR26321.1 - 0.031 14.7 0.5 0.31 11.5 0.1 3.0 2 1 0 2 2 2 0 HEAT-like repeat Cnd1 PF12717.2 CAR26321.1 - 0.18 11.6 11.8 0.1 12.4 0.5 3.9 1 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 DUF1510 PF07423.6 CAR26322.1 - 0.012 15.0 4.7 0.013 14.9 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CobT PF06213.7 CAR26322.1 - 0.014 14.5 4.5 0.012 14.7 3.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ycf1 PF05758.7 CAR26322.1 - 0.079 10.6 1.0 0.079 10.6 0.7 1.0 1 0 0 1 1 1 0 Ycf1 Zip PF02535.17 CAR26322.1 - 0.09 11.7 0.5 0.097 11.6 0.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter MAGP PF05507.6 CAR26322.1 - 0.17 11.7 2.3 0.21 11.3 1.6 1.2 1 0 0 1 1 1 0 Microfibril-associated glycoprotein (MAGP) Hid1 PF12722.2 CAR26322.1 - 1 6.9 5.6 0.99 7.0 3.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pox_Ag35 PF03286.9 CAR26322.1 - 1.6 8.2 8.5 2.4 7.6 5.9 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RR_TM4-6 PF06459.7 CAR26322.1 - 2.6 7.8 11.0 3 7.6 7.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Rcd1 PF04078.8 CAR26323.1 - 4.3e-120 399.4 3.9 5.2e-120 399.2 2.7 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like SRX PF09201.5 CAR26323.1 - 0.024 14.3 0.0 6.7 6.3 0.0 2.4 2 0 0 2 2 2 0 SRX RNase_H2-Ydr279 PF09468.5 CAR26324.1 - 0.6 9.2 9.7 0.6 9.2 6.7 1.0 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) EIIBC-GUT_N PF03612.9 CAR26324.1 - 0.66 9.5 3.5 0.63 9.6 2.4 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF972 PF06156.8 CAR26324.1 - 1.3 9.3 6.0 1.6 9.1 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) FKBP_N PF01346.13 CAR26324.1 - 2.3 8.2 9.4 2.5 8.1 6.5 1.1 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase MMR1 PF08505.5 CAR26324.1 - 2.8 7.9 8.7 3 7.8 6.0 1.0 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DDRGK PF09756.4 CAR26324.1 - 4.9 6.5 13.0 5.5 6.3 9.0 1.1 1 0 0 1 1 1 0 DDRGK domain Ax_dynein_light PF10211.4 CAR26324.1 - 5.6 6.7 9.9 6 6.6 6.8 1.0 1 0 0 1 1 1 0 Axonemal dynein light chain SseC PF04888.7 CAR26324.1 - 6 6.0 7.6 6.1 6.0 5.3 1.0 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family RR_TM4-6 PF06459.7 CAR26324.1 - 9.4 6.0 14.3 9 6.1 9.9 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Y_phosphatase3 PF13350.1 CAR26325.1 - 3e-40 138.1 0.0 6.4e-40 137.0 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family Abhydrolase_5 PF12695.2 CAR26325.1 - 1.5e-09 37.8 0.0 2.7e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CAR26325.1 - 3.9e-07 30.1 0.0 6.2e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Y_phosphatase3C PF13348.1 CAR26325.1 - 5.5e-05 23.1 0.0 0.00016 21.7 0.0 1.8 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Hydrolase_4 PF12146.3 CAR26325.1 - 9.9e-05 22.1 0.0 0.00023 20.9 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase PTPlike_phytase PF14566.1 CAR26325.1 - 0.0023 18.0 0.2 0.0065 16.5 0.0 1.8 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.8 CAR26325.1 - 0.025 13.9 0.0 0.05 12.9 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Ank_4 PF13637.1 CAR26326.1 - 8e-15 54.9 1.7 1.2e-06 28.8 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CAR26326.1 - 8.9e-15 54.8 0.7 2.4e-07 30.9 0.0 3.4 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CAR26326.1 - 2.6e-14 52.8 2.6 9.7e-06 25.6 0.0 4.0 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CAR26326.1 - 6.8e-12 44.4 0.3 0.00099 19.1 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.25 CAR26326.1 - 9.2e-12 44.1 0.2 0.0023 17.6 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat KilA-N PF04383.8 CAR26326.1 - 4.4e-07 29.5 0.1 4.4e-07 29.5 0.1 2.6 2 1 0 2 2 2 1 KilA-N domain COG5 PF10392.4 CAR26326.1 - 6.1 6.8 9.7 0.24 11.3 0.2 3.0 2 1 1 3 3 3 0 Golgi transport complex subunit 5 NTP_transferase PF00483.18 CAR26327.1 - 1.5e-48 165.2 0.0 2.2e-48 164.7 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 CAR26327.1 - 4.5e-11 43.0 0.0 6.2e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 CAR26327.1 - 1.7e-09 36.7 5.6 1.3e-08 33.9 0.9 3.4 1 1 2 3 3 3 1 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CAR26327.1 - 0.037 13.5 5.2 0.038 13.5 0.2 3.0 4 0 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase IspD PF01128.14 CAR26327.1 - 0.08 12.4 0.0 0.46 9.9 0.0 2.1 2 0 0 2 2 2 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.14 CAR26327.1 - 0.17 11.4 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase FA_hydroxylase PF04116.8 CAR26328.1 - 6.2e-16 58.8 21.6 6.2e-16 58.8 14.9 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily TcpE PF12648.2 CAR26328.1 - 0.3 11.2 0.1 0.3 11.2 0.1 2.6 3 0 0 3 3 3 0 TcpE family Glyco_hydro_85 PF03644.8 CAR26329.1 - 3.7e-70 236.5 5.5 4.6e-70 236.2 3.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 SecY PF00344.15 CAR26330.1 - 4.3e-89 298.8 14.9 5.5e-89 298.4 10.3 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 CAR26330.1 - 3.9e-18 64.6 2.4 5.7e-18 64.1 0.1 2.6 2 0 0 2 2 2 1 Plug domain of Sec61p Claudin_3 PF06653.6 CAR26330.1 - 0.24 11.1 0.0 0.24 11.1 0.0 3.1 3 1 0 3 3 3 0 Tight junction protein, Claudin-like MFS_1 PF07690.11 CAR26331.1 - 1.5e-11 43.6 30.9 2.6e-11 42.8 21.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily SEN1_N PF12726.2 CAR26332.1 - 0.048 11.7 3.2 0.056 11.4 2.2 1.0 1 0 0 1 1 1 0 SEN1 N terminal Menin PF05053.8 CAR26332.1 - 0.4 8.7 8.5 0.5 8.4 5.9 1.1 1 0 0 1 1 1 0 Menin Myb_DNA-bind_3 PF12776.2 CAR26332.1 - 6.2 7.5 10.4 0.54 10.9 3.5 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain TFIIA PF03153.8 CAR26332.1 - 8.9 6.0 20.9 9.8 5.9 14.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FBPase PF00316.15 CAR26333.1 - 1.9e-130 434.4 0.0 2.2e-130 434.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 CAR26333.1 - 0.035 13.4 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 Inositol monophosphatase family Acyltransferase PF01553.16 CAR26334.1 - 7.6e-34 115.9 0.0 1.1e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase AAA_25 PF13481.1 CAR26335.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF3944 PF13099.1 CAR26335.1 - 0.14 11.6 0.0 0.35 10.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3944) UPF0731 PF14982.1 CAR26335.1 - 0.16 11.8 0.2 31 4.5 0.0 2.7 3 0 0 3 3 3 0 UPF0731 family La PF05383.12 CAR26336.1 - 1e-22 79.6 0.0 3.2e-22 78.1 0.0 1.9 2 0 0 2 2 2 1 La domain RRM_1 PF00076.17 CAR26336.1 - 4.4e-07 29.4 0.9 2e-06 27.3 0.1 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR26336.1 - 2.8e-06 27.2 0.1 5.2e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR26336.1 - 0.056 13.3 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KRE9 PF05390.6 CAR26337.1 - 2.9e-41 140.1 3.1 6.5e-41 139.0 2.2 1.5 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.4 CAR26337.1 - 4.4e-10 39.9 0.3 1.2e-09 38.5 0.1 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family FA_desaturase PF00487.19 CAR26338.1 - 3.3e-21 75.9 20.8 4.8e-21 75.3 14.4 1.1 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 CAR26338.1 - 0.023 14.6 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) zf-C2H2_6 PF13912.1 CAR26339.1 - 6.3e-06 25.9 7.2 0.00059 19.6 0.2 4.1 3 1 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.21 CAR26339.1 - 0.00039 20.6 1.6 0.00039 20.6 1.1 5.0 4 1 0 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CAR26339.1 - 0.00054 20.1 1.5 0.00054 20.1 1.1 4.9 5 0 0 5 5 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CAR26339.1 - 0.0015 18.5 2.5 0.089 12.9 0.0 3.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 CAR26339.1 - 0.003 17.7 2.4 0.003 17.7 1.7 5.0 4 1 1 5 5 5 1 Zinc-finger double domain zf-RING_2 PF13639.1 CAR26339.1 - 0.017 14.9 1.5 5.6 6.8 0.0 3.4 3 0 0 3 3 3 0 Ring finger domain zf-Di19 PF05605.7 CAR26339.1 - 0.017 15.2 8.1 0.05 13.7 2.7 3.5 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.9 CAR26339.1 - 0.093 12.2 2.1 0.47 9.9 0.1 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_3 PF14369.1 CAR26339.1 - 0.2 11.7 4.9 0.61 10.1 0.1 3.2 3 0 0 3 3 3 0 zinc-finger zf-RING_5 PF14634.1 CAR26339.1 - 0.33 10.7 5.0 10 5.9 0.1 3.2 3 0 0 3 3 3 0 zinc-RING finger domain zf-CHCC PF10276.4 CAR26339.1 - 0.76 9.6 4.0 5.5 6.9 0.1 3.5 4 0 0 4 4 4 0 Zinc-finger domain NADH-G_4Fe-4S_3 PF10588.4 CAR26339.1 - 0.89 8.8 4.0 1.3 8.3 0.3 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region zf-C3HC4_3 PF13920.1 CAR26339.1 - 2.5 7.8 10.5 17 5.2 0.5 3.3 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-met PF12874.2 CAR26339.1 - 6.2 7.1 8.3 0.48 10.7 0.2 3.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type ELO PF01151.13 CAR26340.1 - 8.2e-59 198.9 25.4 1e-58 198.5 17.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family MARVEL PF01284.18 CAR26340.1 - 1.5 8.6 11.6 2.2 8.0 0.5 2.4 2 1 0 2 2 2 0 Membrane-associating domain CNH PF00780.17 CAR26341.1 - 8.7e-77 258.2 0.8 1.2e-76 257.7 0.1 1.6 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 CAR26341.1 - 8.7e-37 126.0 0.0 3.7e-36 124.0 0.0 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 CAR26341.1 - 1.4e-30 106.5 0.3 3.7e-30 105.1 0.0 1.9 2 0 0 2 2 2 1 RhoGEF domain DEP PF00610.16 CAR26341.1 - 2.7e-12 46.2 0.0 7e-12 44.9 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) TraG_N PF07916.6 CAR26341.1 - 0.1 11.0 3.4 0.31 9.4 0.1 2.6 3 0 0 3 3 3 0 TraG-like protein, N-terminal region P21-Arc PF04062.9 CAR26342.1 - 3.4e-73 245.1 0.1 3.8e-73 244.9 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit HSP70 PF00012.15 CAR26343.1 - 1.8e-218 726.3 8.6 2.2e-218 726.0 5.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CAR26343.1 - 1.7e-16 59.7 1.3 7.8e-14 50.9 0.1 2.6 2 1 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 CAR26343.1 - 0.00079 19.0 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 CAR26343.1 - 0.012 15.4 0.6 1.9 8.3 0.0 3.4 2 1 0 2 2 2 0 Cell division protein FtsA B5 PF03484.10 CAR26343.1 - 0.09 12.6 0.6 2 8.3 0.0 3.1 3 1 0 3 3 3 0 tRNA synthetase B5 domain F-box PF00646.28 CAR26344.1 - 4.5e-05 22.9 1.1 0.00019 20.9 0.7 2.2 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CAR26344.1 - 0.12 12.1 2.7 0.32 10.7 0.8 2.5 3 0 0 3 3 3 0 F-box-like zf-C2H2 PF00096.21 CAR26345.1 - 1.6e-08 34.3 12.2 0.00019 21.5 0.9 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CAR26345.1 - 9.7e-08 31.8 12.8 0.0015 18.7 2.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CAR26345.1 - 1.3e-07 31.4 17.1 1.5e-05 25.0 2.7 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 CAR26345.1 - 0.12 12.3 5.2 1.3 8.9 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.7 CAR26345.1 - 1.9 8.6 5.3 6.4 6.9 3.7 1.9 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 CAR26345.1 - 2 8.6 6.3 27 5.0 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 CAR26345.1 - 2.6 8.4 7.1 0.55 10.5 0.6 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Ribosomal_S8 PF00410.14 CAR26346.1 - 5.1e-26 91.0 0.1 7e-26 90.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 MFS_1 PF07690.11 CAR26347.1 - 8.2e-19 67.5 19.8 3.6e-17 62.1 12.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Bmp PF02608.9 CAR26347.1 - 0.062 12.0 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 Basic membrane protein Glutaredoxin PF00462.19 CAR26348.1 - 4.3e-06 26.6 0.0 1.4e-05 24.9 0.0 1.8 1 1 1 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 CAR26348.1 - 0.0006 19.4 0.0 0.00076 19.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.1 CAR26348.1 - 0.00068 19.1 0.0 0.00081 18.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CAR26348.1 - 0.018 15.1 0.1 0.028 14.5 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.1 CAR26348.1 - 0.019 15.1 0.0 0.03 14.5 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain DUF953 PF06110.6 CAR26348.1 - 0.028 13.8 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Spt4 PF06093.8 CAR26349.1 - 3.2e-29 100.6 0.4 3.7e-29 100.4 0.3 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger zf-TFIIB PF13453.1 CAR26349.1 - 0.031 13.4 0.5 0.054 12.6 0.3 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger 60KD_IMP PF02096.15 CAR26350.1 - 2e-15 56.9 7.5 2.4e-14 53.4 5.2 2.0 1 1 0 1 1 1 1 60Kd inner membrane protein DUF2462 PF09495.5 CAR26351.1 - 2.9e-18 66.3 11.2 2.9e-18 66.3 7.8 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) ComC PF03047.9 CAR26351.1 - 0.36 10.2 3.4 1.2 8.5 2.4 1.9 1 0 0 1 1 1 0 COMC family Vma12 PF11712.3 CAR26351.1 - 3 7.5 5.7 0.74 9.5 0.9 1.8 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase GATase_5 PF13507.1 CAR26352.1 - 3e-99 331.1 0.0 4.4e-99 330.5 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 CAR26352.1 - 7.3e-48 162.4 0.1 1.8e-25 89.7 0.0 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 CAR26352.1 - 4.7e-23 81.2 0.0 1.9e-22 79.3 0.0 2.1 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain FA_hydroxylase PF04116.8 CAR26353.1 - 1.5e-16 60.7 18.9 1.5e-16 60.7 13.1 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily PIN_4 PF13638.1 CAR26354.1 - 3.5e-05 23.9 0.0 5.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 PIN domain Septin PF00735.13 CAR26355.1 - 3.2e-89 298.6 0.1 5e-89 298.0 0.0 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 CAR26355.1 - 0.00067 19.5 0.0 0.0038 17.1 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 CAR26355.1 - 0.0011 18.2 0.0 0.0025 17.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 CAR26355.1 - 0.0024 17.3 0.1 0.036 13.5 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain T2SE PF00437.15 CAR26355.1 - 0.017 14.0 0.0 0.032 13.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_10 PF12846.2 CAR26355.1 - 0.024 14.0 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_24 PF13479.1 CAR26355.1 - 0.027 14.0 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 CAR26355.1 - 0.097 12.4 2.7 9 6.0 0.0 3.2 2 1 0 3 3 3 0 Dynamin family ATP_bind_1 PF03029.12 CAR26355.1 - 0.11 12.0 0.7 1 8.8 0.0 2.7 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein EF-hand_7 PF13499.1 CAR26356.1 - 2.3e-06 27.6 0.8 0.00048 20.1 0.1 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CAR26356.1 - 4.8e-05 22.8 0.2 0.1 12.5 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 CAR26356.1 - 0.0014 17.8 0.0 2.4 7.6 0.0 3.8 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.1 CAR26356.1 - 0.0014 18.1 0.0 0.05 13.2 0.0 3.2 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 CAR26356.1 - 0.053 12.8 0.0 26 4.3 0.0 3.4 3 0 0 3 3 3 0 EF hand Pkinase PF00069.20 CAR26357.1 - 1.4e-67 227.5 0.1 6e-66 222.2 0.1 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR26357.1 - 1.3e-48 165.3 0.3 3.5e-46 157.3 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 CAR26357.1 - 1.4e-35 121.4 0.0 3e-35 120.3 0.0 1.6 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.12 CAR26357.1 - 1.1e-10 41.2 0.0 3.1e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CAR26357.1 - 1.1e-09 38.3 0.0 2.7e-09 37.0 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 CAR26357.1 - 1.2e-05 24.4 0.6 0.0003 19.8 0.0 2.5 3 0 0 3 3 3 1 Kinase-like Metallophos PF00149.23 CAR26359.1 - 5e-09 35.8 1.2 1.5e-08 34.3 0.8 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CAR26359.1 - 2.1e-08 34.1 0.1 8e-08 32.2 0.0 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Atg14 PF10186.4 CAR26360.1 - 1.4e-06 27.4 3.9 2.2e-06 26.8 2.7 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF4320 PF14208.1 CAR26360.1 - 0.045 13.6 0.2 5.4 6.9 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4320) Asp23 PF03780.8 CAR26360.1 - 0.098 12.9 0.3 0.18 12.1 0.2 1.4 1 0 0 1 1 1 0 Asp23 family Adeno_E3B PF03376.9 CAR26360.1 - 5.4 6.9 6.1 6.5 6.7 0.7 2.7 3 0 0 3 3 3 0 Adenovirus E3B protein Folliculin PF11704.3 CAR26361.1 - 2.5e-53 180.1 0.8 3e-53 179.8 0.6 1.1 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Lyase_1 PF00206.15 CAR26362.1 - 3.4e-25 88.8 0.0 6.8e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 CAR26362.1 - 6e-17 61.4 0.0 2.8e-16 59.3 0.0 2.2 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus DUF1331 PF07048.6 CAR26362.1 - 0.24 10.9 1.3 0.34 10.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1331) Bromodomain PF00439.20 CAR26363.1 - 6.8e-29 99.6 4.0 1.1e-14 54.0 0.3 2.7 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 CAR26363.1 - 1.3e-21 76.5 0.2 3.3e-21 75.2 0.1 1.8 2 0 0 2 2 2 1 BAH domain Beta_protein PF14350.1 CAR26363.1 - 0.019 14.1 0.1 0.038 13.1 0.0 1.4 1 0 0 1 1 1 0 Beta protein SIR2 PF02146.12 CAR26364.1 - 4.2e-35 121.0 0.0 1e-24 87.2 0.0 2.2 2 0 0 2 2 2 2 Sir2 family AA_permease_2 PF13520.1 CAR26365.1 - 1.3e-81 274.3 47.7 1.6e-81 274.0 33.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CAR26365.1 - 2e-20 72.6 40.9 2.8e-20 72.1 28.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1625 PF07787.7 CAR26365.1 - 7.6 5.6 9.8 0.38 9.9 1.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1625) eIF2A PF08662.6 CAR26366.1 - 1.8e-77 259.4 0.1 1.2e-76 256.8 0.0 2.2 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 CAR26366.1 - 0.00033 20.4 0.8 2.3 8.2 0.1 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat IlvC PF01450.14 CAR26369.1 - 6.6e-47 159.0 0.0 1.4e-46 158.0 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.7 CAR26369.1 - 8.2e-45 152.1 0.0 1.2e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 CAR26369.1 - 0.02 14.7 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase PFK PF00365.15 CAR26370.1 - 1.1e-168 559.3 0.5 1.2e-123 411.5 0.8 2.1 2 0 0 2 2 2 2 Phosphofructokinase TgMIC1 PF11476.3 CAR26370.1 - 0.057 12.9 0.9 0.44 10.0 0.0 2.4 2 0 0 2 2 2 0 Toxoplasma gondii micronemal protein 1 TgMIC1 ORF6C PF10552.4 CAR26372.1 - 0.014 15.1 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 ORF6C domain Dor1 PF04124.7 CAR26372.1 - 0.014 13.8 0.1 0.028 12.8 0.1 1.4 1 0 0 1 1 1 0 Dor1-like family RasGAP_C PF03836.10 CAR26372.1 - 0.047 13.3 1.2 0.084 12.5 0.1 1.8 2 0 0 2 2 2 0 RasGAP C-terminus Seryl_tRNA_N PF02403.17 CAR26372.1 - 0.066 13.2 0.5 0.15 12.0 0.2 1.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TSA PF03249.8 CAR26373.1 - 8 4.8 12.7 15 3.9 8.8 1.4 1 0 0 1 1 1 0 Type specific antigen Kelch_3 PF13415.1 CAR26374.1 - 3e-38 129.1 2.3 1.8e-08 34.3 0.0 5.9 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.1 CAR26374.1 - 3.4e-29 100.2 7.5 0.00082 19.2 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.1 CAR26374.1 - 5.2e-29 99.7 13.1 6.1e-05 22.7 0.2 6.7 5 2 1 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.20 CAR26374.1 - 1.1e-23 82.5 3.4 6e-08 32.0 0.0 5.8 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.1 CAR26374.1 - 1.5e-23 81.8 6.0 1.7e-05 24.8 0.1 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 CAR26374.1 - 1.8e-12 46.4 6.8 0.00029 20.4 0.0 5.9 6 1 0 6 6 6 3 Kelch motif Reo_sigmaC PF04582.7 CAR26374.1 - 0.99 8.5 9.0 1.1 8.4 1.0 2.5 2 1 0 2 2 2 0 Reovirus sigma C capsid protein FUSC PF04632.7 CAR26374.1 - 3.5 5.9 3.8 5.3 5.3 2.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Collagen PF01391.13 CAR26374.1 - 7.5 6.1 40.6 0.88 9.1 24.5 2.2 2 1 0 2 2 2 0 Collagen triple helix repeat (20 copies) Syntaphilin PF15290.1 CAR26376.1 - 0.0012 18.3 0.0 0.0033 16.9 0.0 1.7 1 0 0 1 1 1 1 Golgi-localised syntaxin-1-binding clamp Intron_maturas2 PF01348.16 CAR26376.1 - 0.01 15.8 0.2 0.01 15.8 0.1 1.9 2 0 0 2 2 2 0 Type II intron maturase DUF3046 PF11248.3 CAR26377.1 - 0.03 14.3 0.0 0.037 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3046) ATP-synt_J PF04911.7 CAR26378.1 - 2.6e-24 84.4 2.7 2.8e-24 84.3 1.9 1.0 1 0 0 1 1 1 1 ATP synthase j chain Cys_Met_Meta_PP PF01053.15 CAR26379.1 - 1.9e-28 98.8 0.0 8.7e-28 96.6 0.0 1.9 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme PDE6_gamma PF04868.7 CAR26379.1 - 0.11 12.4 0.0 0.33 10.8 0.0 1.9 1 0 0 1 1 1 0 Retinal cGMP phosphodiesterase, gamma subunit Aminotran_1_2 PF00155.16 CAR26379.1 - 0.11 11.3 0.0 0.61 8.9 0.0 1.9 2 0 0 2 2 2 0 Aminotransferase class I and II Glyco_hydro_47 PF01532.15 CAR26380.1 - 1.2e-143 479.1 0.4 1.3e-143 478.9 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Ctf8 PF09696.5 CAR26381.1 - 3.9e-25 88.0 0.0 5.9e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Ctf8 DUF2296 PF10058.4 CAR26382.1 - 3.9e-12 45.7 0.3 6.9e-12 44.9 0.2 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) DUF4337 PF14235.1 CAR26382.1 - 0.00054 19.8 0.6 0.00054 19.8 0.4 2.7 1 1 1 2 2 1 1 Domain of unknown function (DUF4337) DASH_Duo1 PF08651.5 CAR26382.1 - 0.0016 17.9 6.1 0.14 11.7 0.9 2.8 2 1 1 3 3 3 2 DASH complex subunit Duo1 DUF3180 PF11377.3 CAR26382.1 - 0.019 14.7 0.1 0.029 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3180) IncA PF04156.9 CAR26382.1 - 0.057 13.0 15.8 0.85 9.1 3.6 2.7 2 1 0 2 2 2 0 IncA protein AAA_13 PF13166.1 CAR26382.1 - 0.071 11.5 11.4 0.9 7.9 0.1 2.0 2 0 0 2 2 2 0 AAA domain RseC_MucC PF04246.7 CAR26382.1 - 0.14 11.7 0.3 0.31 10.6 0.0 1.7 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Phage_lysis PF03245.8 CAR26382.1 - 0.18 11.7 11.3 1.1 9.2 0.2 3.2 3 0 0 3 3 3 0 Bacteriophage Rz lysis protein DUF948 PF06103.6 CAR26382.1 - 0.23 11.3 2.0 17 5.3 0.1 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Snapin_Pallidin PF14712.1 CAR26382.1 - 0.29 11.4 10.9 0.76 10.1 0.4 3.1 3 0 0 3 3 3 0 Snapin/Pallidin Seryl_tRNA_N PF02403.17 CAR26382.1 - 0.29 11.1 14.1 1.7 8.6 0.1 3.0 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Syntaxin_2 PF14523.1 CAR26382.1 - 0.33 10.9 17.5 0.31 11.0 0.5 2.6 2 1 0 2 2 2 0 Syntaxin-like protein DUF964 PF06133.6 CAR26382.1 - 0.84 9.6 16.9 0.048 13.6 2.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF964) CorA PF01544.13 CAR26382.1 - 1.2 8.1 9.3 1.7 7.5 0.2 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein NPV_P10 PF05531.7 CAR26382.1 - 1.5 9.0 4.6 1.3 9.3 0.1 2.7 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4473 PF14747.1 CAR26382.1 - 1.9 8.7 10.7 13 6.0 0.1 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4473) HAP1_N PF04849.8 CAR26382.1 - 2.2 7.1 15.1 0.093 11.6 0.6 2.3 2 1 0 2 2 2 0 HAP1 N-terminal conserved region DUF919 PF06034.6 CAR26382.1 - 2.6 7.7 10.8 2.5 7.7 0.4 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF919) TcdB_N PF12918.2 CAR26382.1 - 3.6 7.7 12.2 0.99 9.5 0.2 3.8 3 2 0 3 3 3 0 TcdB toxin N-terminal helical domain DUF4446 PF14584.1 CAR26382.1 - 5.1 6.9 9.5 5.5 6.8 0.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) Baculo_p24 PF05073.7 CAR26382.1 - 6.1 6.3 8.1 11 5.4 1.0 2.3 1 1 1 2 2 2 0 Baculovirus P24 capsid protein DUF342 PF03961.8 CAR26382.1 - 6.5 5.0 11.3 6.7 5.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DUF3573 PF12097.3 CAR26382.1 - 8.4 4.8 8.9 0.91 8.0 1.8 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3573) DUF4239 PF14023.1 CAR26382.1 - 10 5.4 7.1 5.9 6.1 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF4239) NAC PF01849.13 CAR26383.1 - 9.7e-19 66.6 0.4 2.3e-18 65.4 0.0 1.8 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 CAR26383.1 - 5.5e-05 22.8 0.0 0.00012 21.7 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain MDM31_MDM32 PF08118.6 CAR26384.1 - 3.8e-272 903.1 2.0 4.4e-272 902.9 1.4 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins PLRV_ORF5 PF01690.12 CAR26385.1 - 0.036 13.2 4.0 0.049 12.7 2.7 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein IBN_N PF03810.14 CAR26386.1 - 3.6e-13 49.2 0.0 3.8e-12 45.9 0.0 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain Utp12 PF04003.7 CAR26387.1 - 0.0029 17.5 0.2 0.0054 16.6 0.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family TMF_TATA_bd PF12325.3 CAR26388.1 - 1.9e-35 121.2 20.8 1.9e-35 121.2 14.4 5.8 3 1 2 6 6 6 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 CAR26388.1 - 1.6e-16 59.8 8.5 1.6e-16 59.8 5.9 9.8 4 4 5 10 10 10 3 TATA element modulatory factor 1 DNA binding IncA PF04156.9 CAR26388.1 - 0.0009 18.8 17.5 0.0009 18.8 12.1 5.1 2 1 2 4 4 4 2 IncA protein DUF812 PF05667.6 CAR26388.1 - 0.0039 15.7 15.2 0.0039 15.7 10.5 3.5 2 1 1 3 3 3 1 Protein of unknown function (DUF812) CENP-Q PF13094.1 CAR26388.1 - 0.004 17.2 17.7 0.004 17.2 12.3 5.4 2 1 3 5 5 5 2 CENP-Q, a CENPA-CAD centromere complex subunit Reo_sigmaC PF04582.7 CAR26388.1 - 0.05 12.7 29.6 0.16 11.1 4.0 4.0 3 1 0 3 3 3 0 Reovirus sigma C capsid protein Filament PF00038.16 CAR26388.1 - 1.9 7.9 81.7 0.0061 16.0 27.8 4.8 2 2 1 3 3 3 0 Intermediate filament protein DUF1664 PF07889.7 CAR26388.1 - 1.9 8.2 41.9 0.36 10.6 5.0 5.2 2 2 1 4 4 4 0 Protein of unknown function (DUF1664) DUF869 PF05911.6 CAR26388.1 - 6.1 4.9 94.1 1.2 7.3 8.9 3.1 2 1 0 2 2 2 0 Plant protein of unknown function (DUF869) RIX1 PF08167.7 CAR26389.1 - 1.9e-44 151.2 6.3 2.7e-44 150.7 2.8 2.4 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis TLP-20 PF06088.6 CAR26389.1 - 0.99 9.0 7.1 0.046 13.4 0.8 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Transposase_21 PF02992.9 CAR26390.1 - 0.0038 16.3 0.2 0.087 11.8 0.2 2.1 1 1 0 1 1 1 1 Transposase family tnp2 DnaJ-X PF14308.1 CAR26390.1 - 0.054 12.7 1.5 0.1 11.8 0.5 1.7 2 0 0 2 2 2 0 X-domain of DnaJ-containing IncA PF04156.9 CAR26390.1 - 0.091 12.3 0.4 0.14 11.7 0.3 1.3 1 0 0 1 1 1 0 IncA protein zf-Tim10_DDP PF02953.10 CAR26391.1 - 6.5e-21 73.3 3.4 7.8e-21 73.1 2.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Peptidase_S9_N PF02897.10 CAR26391.1 - 0.017 13.7 0.4 0.02 13.4 0.3 1.0 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF445 PF04286.7 CAR26391.1 - 0.068 12.6 0.1 0.076 12.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF1767 PF08585.7 CAR26391.1 - 0.13 12.5 1.4 0.24 11.6 0.3 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1767) DUF2454 PF10521.4 CAR26392.1 - 4.5e-69 232.5 1.4 5.6e-69 232.2 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) Vpu PF00558.14 CAR26392.1 - 0.052 13.1 0.1 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 Vpu protein Chalcone PF02431.10 CAR26393.1 - 1.2e-55 188.0 0.0 1.5e-55 187.7 0.0 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase NIR_SIR PF01077.17 CAR26394.1 - 7.5e-50 168.3 0.0 3.4e-42 143.4 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 CAR26394.1 - 9.3e-28 95.6 0.0 6.8e-14 51.2 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 CAR26394.1 - 9.4e-26 90.5 0.0 2e-25 89.4 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin TPR_MLP1_2 PF07926.7 CAR26395.1 - 0.0085 15.8 1.3 0.0086 15.8 0.9 1.0 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein DUF2536 PF10750.4 CAR26395.1 - 0.045 13.3 0.2 0.048 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2536) VWA_2 PF13519.1 CAR26396.1 - 5e-08 33.2 0.0 6.9e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 CAR26396.1 - 1.7e-07 31.0 0.3 2.5e-07 30.5 0.2 1.2 1 0 0 1 1 1 1 Ssl1-like DUF1887 PF09002.6 CAR26396.1 - 0.0078 14.6 0.3 0.014 13.8 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1887) DUF3682 PF12446.3 CAR26396.1 - 1.4 9.1 13.3 2.5 8.4 8.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) DUF3608 PF12257.3 CAR26397.1 - 4.2e-138 458.9 0.9 7.3e-138 458.1 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 CAR26397.1 - 6.1e-27 93.1 0.1 1.5e-26 91.9 0.1 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Homoserine_dh PF00742.14 CAR26398.1 - 4.2e-57 192.7 0.0 5.7e-57 192.2 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 CAR26398.1 - 3.7e-20 72.4 0.0 7.1e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 CAR26398.1 - 0.014 15.7 0.0 0.031 14.5 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 CAR26398.1 - 0.023 15.1 0.0 0.09 13.2 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.16 CAR26398.1 - 0.079 12.7 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 ThiF family HECT_2 PF09814.4 CAR26400.1 - 2.5e-59 200.8 0.2 2.8e-59 200.6 0.1 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DHHA2 PF02833.9 CAR26401.1 - 2.8e-25 88.9 0.3 4.8e-25 88.2 0.2 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 CAR26401.1 - 2.4e-09 37.0 1.9 6.5e-09 35.5 0.0 2.3 2 2 0 2 2 2 1 DHH family NUDIX PF00293.23 CAR26402.1 - 2.3e-05 24.0 0.0 6.1e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain PMT PF02366.13 CAR26403.1 - 4.4e-75 252.1 21.9 4.4e-75 252.1 15.2 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CAR26403.1 - 3.5e-23 82.1 0.0 6.2e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 MIR domain Mgm101p PF06420.7 CAR26404.1 - 2.1e-89 297.3 0.1 2.5e-89 297.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Lac_bphage_repr PF06543.7 CAR26404.1 - 0.049 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor WD40 PF00400.27 CAR26405.1 - 0.001 18.8 1.6 0.43 10.5 0.0 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat BPL_LplA_LipB PF03099.14 CAR26406.1 - 2.5e-19 69.5 0.1 4.4e-19 68.7 0.1 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF236 PF03057.9 CAR26406.1 - 0.04 13.8 0.1 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function UPF0086 PF01868.11 CAR26407.1 - 1.8e-13 49.9 0.0 3.1e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function UPF0086 COMPASS-Shg1 PF05205.7 CAR26408.1 - 1.5e-22 79.9 1.9 2e-22 79.5 1.3 1.2 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 Coat_F PF07875.7 CAR26409.1 - 0.036 14.2 0.2 0.09 12.9 0.2 1.6 1 0 0 1 1 1 0 Coat F domain Cullin PF00888.17 CAR26410.1 - 1.5e-16 60.0 20.1 3.7e-13 48.8 1.8 2.3 2 0 0 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.4 CAR26410.1 - 0.0017 18.1 0.0 0.0094 15.7 0.0 2.4 1 0 0 1 1 1 1 Cullin protein neddylation domain RhoGAP PF00620.22 CAR26411.1 - 1.7e-39 134.8 0.5 9.7e-39 132.4 0.0 2.3 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 CAR26411.1 - 2.6e-15 56.3 4.0 1.1e-14 54.3 0.1 2.7 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Methyltransf_PK PF05891.7 CAR26412.1 - 2.6e-93 311.3 0.0 2.9e-93 311.1 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.2 CAR26412.1 - 4.9e-06 27.0 0.0 7.8e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAR26412.1 - 1.4e-05 24.9 0.0 2.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CAR26412.1 - 0.00088 19.7 0.0 0.0016 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CAR26412.1 - 0.012 14.6 0.0 0.017 14.2 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 CAR26412.1 - 0.013 15.8 0.0 0.023 15.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 CAR26412.1 - 0.029 14.8 0.0 0.053 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 CAR26412.1 - 0.091 11.9 0.0 0.21 10.7 0.0 1.7 1 1 0 1 1 1 0 O-methyltransferase Bin3 PF06859.7 CAR26412.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) Arb1 PF09692.5 CAR26412.1 - 0.15 10.9 0.0 0.26 10.0 0.0 1.3 1 0 0 1 1 1 0 Argonaute siRNA chaperone (ARC) complex subunit Arb1 SHMT PF00464.14 CAR26414.1 - 1.2e-204 679.2 0.0 1.4e-204 678.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 CAR26414.1 - 0.001 18.2 0.0 0.0018 17.5 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Ras PF00071.17 CAR26415.1 - 1.7e-41 141.3 0.1 1.8e-40 137.9 0.1 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 CAR26415.1 - 1.1e-18 67.8 0.0 1.7e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAR26415.1 - 7.4e-17 61.1 0.0 2.3e-16 59.5 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CAR26415.1 - 1.1e-06 28.5 0.1 1.7e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CAR26415.1 - 9.1e-06 24.9 0.0 1.3e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CAR26415.1 - 3.3e-05 23.1 0.0 0.0001 21.5 0.0 1.7 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 CAR26415.1 - 0.00053 19.4 0.1 0.015 14.7 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CAR26415.1 - 0.026 13.7 0.6 0.075 12.2 0.1 2.0 3 0 0 3 3 3 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 CAR26415.1 - 0.039 14.0 0.1 0.074 13.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain Rif1_N PF12231.3 CAR26416.1 - 7.9e-47 159.9 12.3 1.7e-46 158.8 8.6 1.5 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Pkinase PF00069.20 CAR26417.1 - 3.7e-58 196.7 0.0 4.7e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR26417.1 - 4.3e-30 104.6 0.0 5.6e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR26417.1 - 1.1e-06 27.9 0.0 1.7e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 CAR26417.1 - 0.0023 16.8 0.0 0.0048 15.7 0.0 1.5 1 0 0 1 1 1 1 Seadornavirus VP7 Choline_kinase PF01633.15 CAR26417.1 - 0.12 11.8 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase UBX PF00789.15 CAR26418.1 - 1.3e-16 60.4 0.1 4.6e-16 58.6 0.0 1.9 2 0 0 2 2 2 1 UBX domain 4HB_MCP_1 PF12729.2 CAR26418.1 - 0.04 13.2 0.9 0.086 12.1 0.6 1.5 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction CCP_MauG PF03150.9 CAR26418.1 - 0.049 13.9 0.2 0.096 12.9 0.1 1.4 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Snf7 PF03357.16 CAR26419.1 - 2.3e-16 59.6 16.9 3.4e-16 59.1 11.7 1.2 1 0 0 1 1 1 1 Snf7 DUF1922 PF09082.5 CAR26419.1 - 0.045 13.8 0.3 10 6.2 0.1 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF1922) UBN2 PF14223.1 CAR26419.1 - 0.11 12.3 7.6 0.21 11.3 1.9 2.7 1 1 0 2 2 2 0 gag-polypeptide of LTR copia-type SlyX PF04102.7 CAR26419.1 - 1.4 9.3 6.1 0.82 10.0 0.2 3.0 2 1 0 3 3 3 0 SlyX Vps26 PF03643.10 CAR26420.1 - 9e-112 372.3 0.3 1e-111 372.1 0.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 CAR26420.1 - 0.0016 18.3 0.1 0.008 16.0 0.0 2.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CAR26420.1 - 0.0044 17.1 0.0 0.017 15.2 0.0 1.9 1 1 1 2 2 2 1 Arrestin (or S-antigen), C-terminal domain rRNA_proc-arch PF13234.1 CAR26422.1 - 2.9e-94 315.1 0.5 5.5e-94 314.2 0.3 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 CAR26422.1 - 6.1e-62 208.0 0.4 1.4e-61 206.9 0.2 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 CAR26422.1 - 1.1e-21 77.0 0.0 1.1e-20 73.8 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR26422.1 - 1.2e-06 28.2 0.0 5.3e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Aminotran_1_2 PF00155.16 CAR26424.1 - 6.4e-79 265.5 0.0 7.3e-79 265.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II ING PF12998.2 CAR26425.1 - 1.4e-23 83.1 1.3 1e-22 80.3 0.6 2.0 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 CAR26425.1 - 2.4e-08 33.5 9.5 4.2e-08 32.7 6.6 1.4 1 0 0 1 1 1 1 PHD-finger YlqD PF11068.3 CAR26425.1 - 0.033 14.2 0.1 0.052 13.5 0.1 1.2 1 0 0 1 1 1 0 YlqD protein zf-HC5HC2H PF13771.1 CAR26425.1 - 0.042 13.9 1.1 0.095 12.8 0.7 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain Ras PF00071.17 CAR26426.1 - 5.6e-56 188.3 0.2 7.3e-56 188.0 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR26426.1 - 9.5e-20 71.2 0.1 1.4e-19 70.6 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAR26426.1 - 2.1e-09 36.8 0.1 2.5e-09 36.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CAR26426.1 - 5.9e-05 22.5 0.2 0.00031 20.2 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CAR26426.1 - 6.3e-05 22.9 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CAR26426.1 - 0.083 12.0 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 CAR26426.1 - 0.11 11.9 0.1 0.2 11.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain DAD PF02109.11 CAR26427.1 - 6e-38 129.3 3.3 7.3e-38 129.0 2.3 1.1 1 0 0 1 1 1 1 DAD family PalH PF08733.5 CAR26427.1 - 0.0055 15.5 0.3 0.006 15.4 0.2 1.1 1 0 0 1 1 1 1 PalH/RIM21 COPI_assoc PF08507.5 CAR26427.1 - 0.055 13.1 4.2 0.054 13.1 2.3 1.4 1 1 0 1 1 1 0 COPI associated protein Cystatin PF00031.16 CAR26427.1 - 0.095 12.8 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Cystatin domain Neurensin PF14927.1 CAR26427.1 - 0.11 11.9 0.1 1.3 8.4 0.0 2.0 2 0 0 2 2 2 0 Neurensin Y_phosphatase2 PF03162.8 CAR26428.1 - 2e-58 196.3 0.0 2.9e-58 195.8 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 CAR26428.1 - 9.1e-06 26.0 0.0 3.6e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 CAR26428.1 - 0.058 12.9 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Lamp PF01299.12 CAR26429.1 - 0.012 14.8 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) ApoO PF09769.4 CAR26430.1 - 5.3e-08 32.7 0.3 0.0032 17.2 0.0 3.0 2 1 1 3 3 3 3 Apolipoprotein O Aa_trans PF01490.13 CAR26431.1 - 7e-96 321.1 34.9 8.8e-96 320.8 24.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1049 PF06305.6 CAR26431.1 - 0.014 14.8 0.3 0.084 12.3 0.2 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DNA_pol_B PF00136.16 CAR26433.1 - 3.4e-114 382.1 1.7 5.9e-114 381.4 1.2 1.4 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 CAR26433.1 - 5.2e-61 205.2 5.2 1.1e-60 204.2 3.6 1.6 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 CAR26433.1 - 5.4e-41 140.5 0.0 1e-40 139.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 CAR26433.1 - 1e-14 54.1 9.6 3.4e-14 52.3 6.6 2.0 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal zinc_ribbon_5 PF13719.1 CAR26433.1 - 0.039 13.5 3.3 5.5 6.6 0.1 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CAR26433.1 - 0.13 11.9 3.7 7.8 6.2 0.3 2.9 2 0 0 2 2 2 0 zinc-ribbon domain SNARE PF05739.14 CAR26434.1 - 1.3e-13 50.4 8.6 1.3e-13 50.4 6.0 2.4 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.1 CAR26434.1 - 7.6e-12 45.1 0.7 7.6e-12 45.1 0.5 3.3 2 1 1 3 3 3 1 Syntaxin-like protein Synaptobrevin PF00957.16 CAR26434.1 - 0.00026 20.5 2.8 0.00026 20.5 1.9 2.1 2 0 0 2 2 2 1 Synaptobrevin TrbL PF04610.9 CAR26434.1 - 0.055 13.1 0.0 0.074 12.7 0.0 1.2 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein T2SF PF00482.18 CAR26434.1 - 0.072 13.0 0.3 0.072 13.0 0.2 2.7 3 1 0 3 3 3 0 Type II secretion system (T2SS), protein F DUF3753 PF12575.3 CAR26434.1 - 0.076 12.8 0.2 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) MCPsignal PF00015.16 CAR26434.1 - 0.24 10.9 11.0 0.083 12.4 4.9 1.9 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1373 PF07117.6 CAR26434.1 - 0.57 9.8 3.6 2.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1373) SKI PF01202.17 CAR26434.1 - 0.75 9.6 4.4 1.4 8.7 2.5 1.9 1 1 0 1 1 1 0 Shikimate kinase MutS_IV PF05190.13 CAR26434.1 - 2.4 8.3 6.9 15 5.8 0.0 3.6 4 1 1 5 5 5 0 MutS family domain IV bZIP_2 PF07716.10 CAR26435.1 - 0.0069 16.1 4.9 0.0069 16.1 3.4 3.1 3 0 0 3 3 3 1 Basic region leucine zipper OCC1 PF15506.1 CAR26435.1 - 0.12 12.3 2.4 0.58 10.0 0.1 3.1 2 0 0 2 2 2 0 OCC1 family RGS PF00615.14 CAR26436.1 - 9.4e-14 51.5 1.4 9.4e-14 51.5 1.0 1.7 2 0 0 2 2 2 1 Regulator of G protein signaling domain HMGL-like PF00682.14 CAR26437.1 - 7.7e-75 251.5 0.0 1.1e-74 251.1 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 CAR26437.1 - 8.2e-25 87.1 0.0 1.8e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Syja_N PF02383.13 CAR26438.1 - 6.8e-91 304.3 0.2 1.1e-90 303.6 0.1 1.3 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 CAR26438.1 - 3.4e-26 92.7 0.0 7.1e-26 91.6 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family YEATS PF03366.11 CAR26439.1 - 1.7e-34 117.3 1.6 2.7e-34 116.7 1.1 1.3 1 0 0 1 1 1 1 YEATS family His_Phos_1 PF00300.17 CAR26440.1 - 3.1e-24 85.8 0.0 7.3e-24 84.6 0.0 1.7 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) TFIIIC_sub6 PF10419.4 CAR26440.1 - 6e-15 54.4 0.0 1.9e-14 52.8 0.0 1.8 1 0 0 1 1 1 1 TFIIIC subunit Maf PF02545.9 CAR26441.1 - 7.6e-51 172.0 0.0 9.4e-51 171.7 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein OspD PF03207.8 CAR26441.1 - 0.1 11.7 0.1 0.13 11.3 0.0 1.4 1 1 0 1 1 1 0 Borrelia outer surface protein D (OspD) RRM_1 PF00076.17 CAR26442.1 - 3.3e-19 68.2 1.1 4.7e-19 67.7 0.1 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR26442.1 - 7.7e-13 48.2 0.2 6.7e-12 45.2 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR26442.1 - 1.9e-09 37.2 0.1 3.1e-09 36.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CAR26442.1 - 0.0015 18.2 1.8 0.018 14.7 0.0 2.8 2 1 1 3 3 3 1 Limkain b1 Ax_dynein_light PF10211.4 CAR26442.1 - 1.7 8.4 5.7 2.1 8.1 1.0 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain Cyt-b5 PF00173.23 CAR26443.1 - 1.2e-26 92.2 0.1 2.3e-26 91.3 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CLASP_N PF12348.3 CAR26444.1 - 0.00041 19.7 0.1 0.017 14.4 0.0 2.4 2 0 0 2 2 2 1 CLASP N terminal Cnd1 PF12717.2 CAR26444.1 - 0.002 18.0 1.7 0.081 12.7 0.0 2.9 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 CAR26444.1 - 0.016 15.2 0.1 50 4.3 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat DEAD PF00270.24 CAR26445.1 - 3.4e-45 153.5 0.0 1.8e-43 147.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR26445.1 - 1.1e-29 102.0 0.0 3e-29 100.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAR26445.1 - 0.00065 19.5 0.0 0.0019 18.0 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 CAR26445.1 - 0.0011 17.5 0.0 0.0083 14.5 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1253) Helicase_C_2 PF13307.1 CAR26445.1 - 0.01 15.8 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain GRP PF07172.6 CAR26445.1 - 5.1 7.6 45.1 1 9.8 18.9 2.5 2 0 0 2 2 2 0 Glycine rich protein family RNA_pol_L_2 PF13656.1 CAR26446.1 - 1.4e-31 107.7 0.0 2.2e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 CAR26446.1 - 2.4e-12 45.7 0.0 3.3e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Med14 PF08638.6 CAR26446.1 - 0.069 12.3 0.0 0.086 12.0 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit MED14 GST_N_2 PF13409.1 CAR26447.1 - 1.5e-20 72.9 0.0 1.3e-19 69.9 0.0 2.6 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CAR26447.1 - 3.1e-10 39.8 0.0 8e-10 38.4 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CAR26447.1 - 0.0028 17.8 0.2 0.55 10.5 0.0 2.9 4 0 0 4 4 4 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CAR26447.1 - 0.022 14.7 0.2 0.1 12.6 0.1 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MRP-L27 PF09809.4 CAR26447.1 - 0.075 12.6 0.0 0.39 10.3 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L27 DUF4065 PF13274.1 CAR26448.1 - 0.033 14.9 0.3 3.3 8.4 0.2 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4065) CBF PF03914.12 CAR26450.1 - 1.1e-37 129.0 0.0 1.1e-37 129.0 0.0 2.4 2 1 0 2 2 2 1 CBF/Mak21 family NOC3p PF07540.6 CAR26450.1 - 6.3e-34 116.1 0.1 6.3e-34 116.1 0.1 3.3 2 1 0 2 2 2 1 Nucleolar complex-associated protein HEAT_2 PF13646.1 CAR26450.1 - 0.052 13.8 0.1 3.1 8.1 0.0 3.2 3 0 0 3 3 3 0 HEAT repeats Gti1_Pac2 PF09729.4 CAR26450.1 - 1.2 9.0 8.8 5.6 6.8 0.6 2.5 2 0 0 2 2 2 0 Gti1/Pac2 family SID-1_RNA_chan PF13965.1 CAR26450.1 - 6.6 4.7 10.1 2.5 6.1 0.9 2.2 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Mpp10 PF04006.7 CAR26451.1 - 8.7e-121 404.1 92.9 5.4e-113 378.4 56.5 2.1 1 1 1 2 2 2 2 Mpp10 protein Aa_trans PF01490.13 CAR26452.1 - 9e-81 271.4 19.3 1.1e-80 271.2 13.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Slx4 PF09494.5 CAR26452.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Slx4 endonuclease NumbF PF06311.7 CAR26452.1 - 0.19 11.8 0.2 0.35 11.0 0.1 1.4 1 0 0 1 1 1 0 NUMB domain Alg14 PF08660.6 CAR26452.1 - 0.31 11.0 1.5 0.58 10.1 1.1 1.4 1 0 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like Fasciclin PF02469.17 CAR26453.1 - 2.4e-22 79.2 0.0 5.8e-06 26.3 0.0 5.8 5 1 0 5 5 5 4 Fasciclin domain Dynamin_M PF01031.15 CAR26454.1 - 2.6e-111 371.1 0.0 4.2e-111 370.4 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 CAR26454.1 - 7.9e-54 181.9 0.0 2.8e-53 180.1 0.0 2.0 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 CAR26454.1 - 3.4e-29 100.5 3.0 1.1e-28 98.9 2.1 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 CAR26454.1 - 0.00041 20.2 0.3 0.0059 16.5 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CAR26454.1 - 0.004 17.6 0.1 0.055 13.9 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein zf-CCHC_4 PF14392.1 CAR26454.1 - 0.063 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Zinc knuckle BSMAP PF12280.3 CAR26454.1 - 0.3 10.9 2.3 0.34 10.7 0.6 1.7 1 1 0 1 1 1 0 Brain specific membrane anchored protein KAT11 PF08214.6 CAR26455.1 - 3.1e-90 302.7 0.9 3.8e-90 302.4 0.7 1.0 1 0 0 1 1 1 1 Histone acetylation protein Proteasome PF00227.21 CAR26456.1 - 6.8e-47 159.2 1.0 7.7e-47 159.0 0.7 1.0 1 0 0 1 1 1 1 Proteasome subunit Sfi1 PF08457.5 CAR26457.1 - 3.2e-42 144.6 97.4 5.4e-40 137.3 46.0 2.2 1 1 1 2 2 2 2 Sfi1 spindle body protein Sfi1_C PF10638.4 CAR26457.1 - 9.2e-28 96.8 4.1 2.5e-27 95.4 2.9 1.8 1 0 0 1 1 1 1 Spindle body associated protein C-terminus Ribophorin_I PF04597.9 CAR26458.1 - 5.6e-122 407.3 1.0 6.4e-122 407.1 0.7 1.0 1 0 0 1 1 1 1 Ribophorin I COX16 PF14138.1 CAR26460.1 - 4.1e-29 100.5 0.9 4.1e-29 100.5 0.1 1.4 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein COX16 MFS_1 PF07690.11 CAR26460.1 - 0.021 13.5 0.0 0.027 13.1 0.0 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF221 PF02714.10 CAR26461.1 - 3.5e-93 312.0 23.7 3.5e-93 312.0 16.4 3.0 5 0 0 5 5 5 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CAR26461.1 - 1.6e-26 92.7 6.9 1.6e-26 92.7 4.8 2.5 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 CAR26461.1 - 0.048 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Phosphate metabolism protein DUF3377 PF11857.3 CAR26461.1 - 5.7 6.6 5.3 17 5.1 3.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF2404 PF10296.4 CAR26462.1 - 6.9e-05 22.8 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) DUF2895 PF11444.3 CAR26462.1 - 0.0019 17.4 0.1 0.0033 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2895) DEAD PF00270.24 CAR26464.1 - 2.3e-46 157.3 0.1 5.7e-46 156.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR26464.1 - 6.2e-26 90.0 0.0 2.6e-25 88.1 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SYS1 PF09801.4 CAR26465.1 - 6.7e-48 162.3 16.3 7.8e-48 162.1 11.3 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network PP2C PF00481.16 CAR26466.1 - 7.3e-54 182.8 0.0 1.4e-53 181.8 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 CAR26466.1 - 6.2e-44 146.9 73.9 3.2e-07 29.7 0.9 12.3 7 3 5 13 13 13 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAR26466.1 - 4.8e-40 135.1 70.3 1.5e-09 37.4 3.3 9.9 5 3 4 9 9 9 8 Leucine rich repeat Guanylate_cyc PF00211.15 CAR26466.1 - 7.3e-29 100.4 0.0 1.3e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 CAR26466.1 - 9.9e-16 55.3 71.2 0.025 14.5 0.3 17.9 15 4 3 18 18 18 8 Leucine Rich Repeat RA PF00788.18 CAR26466.1 - 8e-08 32.6 0.0 2.6e-07 31.0 0.0 1.9 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_5 PF13306.1 CAR26466.1 - 1.8e-05 24.4 6.2 0.00012 21.8 0.3 3.2 3 0 0 3 3 3 1 Leucine rich repeats (6 copies) LRR_7 PF13504.1 CAR26466.1 - 6.1e-05 22.5 57.2 1.4 9.4 0.4 15.8 17 0 0 17 17 17 3 Leucine rich repeat LRR_9 PF14580.1 CAR26466.1 - 0.0037 16.8 17.1 0.1 12.1 0.6 4.2 2 1 2 4 4 4 2 Leucine-rich repeat LRR_6 PF13516.1 CAR26466.1 - 3.5 7.9 73.7 1.8 8.9 1.7 15.3 15 3 1 16 16 16 0 Leucine Rich repeat PNP_UDP_1 PF01048.15 CAR26467.1 - 1.2e-33 116.1 0.0 1.4e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily NPCC PF08058.6 CAR26468.1 - 2.3e-31 108.5 1.5 3.9e-31 107.8 1.1 1.4 1 0 0 1 1 1 1 Nuclear pore complex component NIF PF03031.13 CAR26469.1 - 3.1e-50 169.9 0.1 5.7e-50 169.0 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase WD40 PF00400.27 CAR26470.1 - 5.3e-37 124.3 7.1 5.7e-08 32.3 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat Sof1 PF04158.9 CAR26470.1 - 4.3e-28 97.1 10.7 1.1e-27 95.8 7.4 1.7 1 0 0 1 1 1 1 Sof1-like domain BBS2_Mid PF14783.1 CAR26470.1 - 0.00027 20.6 0.6 0.0056 16.4 0.0 3.2 4 1 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Abhydro_lipase PF04083.11 CAR26471.1 - 3.3e-16 58.4 0.1 6e-16 57.5 0.1 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 CAR26471.1 - 0.00048 19.7 0.0 0.001 18.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CAR26471.1 - 0.0005 20.0 0.0 0.00069 19.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family chaperone_DMP PF10448.4 CAR26472.1 - 2.6e-31 108.4 0.0 2.8e-31 108.3 0.0 1.0 1 0 0 1 1 1 1 20S proteasome chaperone SBDS_C PF09377.5 CAR26473.1 - 1.5e-36 124.8 4.3 1.7e-36 124.6 1.0 2.0 2 0 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.13 CAR26473.1 - 7.6e-35 118.5 2.9 1.2e-34 117.9 2.0 1.3 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein XkdN PF08890.6 CAR26473.1 - 0.035 13.8 0.6 0.035 13.8 0.4 2.5 2 1 0 2 2 2 0 Phage XkdN-like protein Arena_glycoprot PF00798.13 CAR26473.1 - 0.06 11.7 1.6 0.067 11.5 1.1 1.2 1 0 0 1 1 1 0 Arenavirus glycoprotein Fer4_14 PF13394.1 CAR26473.1 - 0.11 12.4 0.4 14 5.7 0.0 2.6 2 1 0 2 2 2 0 4Fe-4S single cluster domain HlyIII PF03006.15 CAR26474.1 - 8.9e-66 221.4 16.2 1.3e-65 220.9 11.3 1.2 1 0 0 1 1 1 1 Haemolysin-III related CDC45 PF02724.9 CAR26474.1 - 0.18 9.7 3.7 0.25 9.3 2.5 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.1 CAR26474.1 - 0.51 10.6 10.0 0.99 9.7 6.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PUF PF00806.14 CAR26475.1 - 9.5e-55 179.1 9.0 2.1e-07 30.0 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CBP4 PF07960.6 CAR26475.1 - 0.25 10.9 4.6 0.54 9.8 3.2 1.5 1 0 0 1 1 1 0 CBP4 Rab5ip PF07019.7 CAR26476.1 - 8.4e-20 70.6 4.3 9.9e-20 70.4 2.9 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF383 PF04063.9 CAR26477.1 - 5.3e-71 238.1 0.3 9.6e-71 237.3 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 CAR26477.1 - 6.3e-26 89.7 0.1 1.7e-25 88.2 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF384) PapB PF03333.8 CAR26477.1 - 0.03 14.1 0.1 0.076 12.8 0.0 1.7 1 0 0 1 1 1 0 Adhesin biosynthesis transcription regulatory protein SRI PF08236.6 CAR26477.1 - 0.094 12.6 0.1 19 5.3 0.0 2.7 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain TFIIF_alpha PF05793.7 CAR26478.1 - 2.9e-10 39.1 0.4 2.9e-10 39.1 0.2 3.2 2 1 1 3 3 3 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) tRNA-synt_1b PF00579.20 CAR26479.1 - 3.8e-75 252.7 0.0 5e-75 252.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Tup_N PF08581.5 CAR26479.1 - 0.061 13.5 0.0 0.57 10.4 0.0 2.4 2 0 0 2 2 2 0 Tup N-terminal zf-UBR PF02207.15 CAR26480.1 - 9.4e-13 47.6 12.3 9.4e-13 47.6 8.5 2.7 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) zf-UBR PF02207.15 CAR26481.1 - 1.8e-16 59.6 15.9 1.8e-16 59.6 11.0 2.6 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 CAR26481.1 - 1.1e-07 31.4 0.0 3.6e-07 29.8 0.0 1.9 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.1 CAR26481.1 - 0.00034 20.3 1.1 0.00034 20.3 0.8 3.5 4 0 0 4 4 4 1 Ring finger domain UCR_UQCRX_QCR9 PF05365.7 CAR26482.1 - 2.7e-27 94.1 0.9 3e-27 93.9 0.6 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like zf-Tim10_DDP PF02953.10 CAR26483.1 - 9e-18 63.3 0.8 1.3e-17 62.8 0.6 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF3398 PF11878.3 CAR26483.1 - 0.15 11.8 0.3 0.22 11.3 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3398) Clat_adaptor_s PF01217.15 CAR26484.1 - 3.9e-56 188.7 0.8 4.6e-56 188.4 0.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Orthopox_B11R PF07033.6 CAR26484.1 - 0.0097 15.3 0.9 0.1 12.1 0.0 2.3 2 0 0 2 2 2 1 Orthopoxvirus B11R protein MCPsignal PF00015.16 CAR26484.1 - 0.076 12.5 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain TFIID_20kDa PF03847.8 CAR26484.1 - 0.82 9.9 2.9 1.6 9.0 0.0 2.6 3 0 0 3 3 3 0 Transcription initiation factor TFIID subunit A CBP4 PF07960.6 CAR26485.1 - 2.5e-48 162.8 5.3 3.1e-48 162.5 3.7 1.1 1 0 0 1 1 1 1 CBP4 DUF3419 PF11899.3 CAR26485.1 - 0.021 13.5 0.1 0.025 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) KMP11 PF03037.11 CAR26485.1 - 0.13 12.8 3.5 1.5 9.4 0.6 2.2 2 0 0 2 2 2 0 Kinetoplastid membrane protein 11 Wbp11 PF09429.5 CAR26485.1 - 1.9 8.5 11.7 1 9.3 4.3 2.2 2 0 0 2 2 2 0 WW domain binding protein 11 DUF4558 PF15104.1 CAR26485.1 - 4.9 7.1 11.9 0.54 10.2 2.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4558) SE PF08491.5 CAR26486.1 - 1.2e-119 398.2 0.0 1.5e-119 397.9 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 CAR26486.1 - 8.5e-15 54.6 0.0 1.4e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 CAR26486.1 - 1.8e-07 30.3 0.1 4.4e-05 22.5 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 CAR26486.1 - 0.00045 20.5 0.7 0.0013 19.1 0.1 2.1 2 1 1 3 3 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CAR26486.1 - 0.0013 18.6 0.1 0.0025 17.7 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CAR26486.1 - 0.0022 17.9 0.1 0.005 16.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 CAR26486.1 - 0.0049 16.5 0.1 0.0076 15.9 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 CAR26486.1 - 0.0069 15.2 1.9 0.0096 14.8 0.4 1.7 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 CAR26486.1 - 0.0077 15.3 0.1 0.012 14.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Shikimate_DH PF01488.15 CAR26486.1 - 0.0094 16.0 0.1 0.018 15.1 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 CAR26486.1 - 0.016 15.5 0.1 0.033 14.5 0.1 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GDI PF00996.13 CAR26486.1 - 0.044 12.0 0.0 0.07 11.4 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor TrkA_N PF02254.13 CAR26486.1 - 0.047 13.6 0.1 0.089 12.7 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.18 CAR26486.1 - 0.061 13.0 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 CAR26486.1 - 0.096 12.0 0.1 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_oxidored PF12831.2 CAR26486.1 - 0.1 11.6 1.1 0.24 10.4 0.3 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 CAR26486.1 - 0.18 10.2 1.3 0.28 9.5 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.17 CAR26486.1 - 0.24 10.1 0.8 0.33 9.7 0.1 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 CAR26486.1 - 0.3 9.9 2.4 1.1 8.1 0.1 2.5 4 0 0 4 4 4 0 Lycopene cyclase protein RRN7 PF11781.3 CAR26487.1 - 6.8e-10 38.2 0.3 6.8e-10 38.2 0.2 1.7 2 0 0 2 2 2 1 RNA polymerase I-specific transcription initiation factor Rrn7 LsmAD PF06741.8 CAR26488.1 - 2.9e-28 97.7 1.5 2.9e-28 97.7 1.1 2.6 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.1 CAR26488.1 - 2.1e-16 59.6 0.0 6.3e-16 58.0 0.0 1.9 1 0 0 1 1 1 1 Ataxin 2 SM domain CENP-Q PF13094.1 CAR26489.1 - 0.00081 19.4 8.2 0.00081 19.4 5.7 2.3 3 1 0 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF755 PF05501.6 CAR26489.1 - 0.061 13.3 2.2 0.16 12.0 1.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF4206 PF13901.1 CAR26489.1 - 1.3 8.5 3.9 0.62 9.5 0.2 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4206) UCH PF00443.24 CAR26490.1 - 7.7e-55 185.8 0.9 1.3e-54 185.1 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CAR26490.1 - 4.1e-10 39.5 0.1 4.1e-10 39.5 0.1 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Tom37_C PF11801.3 CAR26490.1 - 0.041 13.7 2.0 0.43 10.4 2.2 2.0 2 0 0 2 2 2 0 Tom37 C-terminal domain DEC-1_N PF04625.8 CAR26490.1 - 3.1 6.3 10.6 5.1 5.6 7.3 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Aminotran_1_2 PF00155.16 CAR26492.1 - 9.4e-19 67.5 0.0 1.1e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 CAR26492.1 - 2.5e-05 23.0 0.0 3.8e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase PI3K_p85B PF02192.11 CAR26492.1 - 0.012 15.0 0.0 0.035 13.5 0.0 1.8 2 0 0 2 2 2 0 PI3-kinase family, p85-binding domain PET122 PF05476.6 CAR26493.1 - 6.1e-90 301.0 0.4 7.4e-90 300.8 0.3 1.0 1 0 0 1 1 1 1 PET122 COX6A PF02046.10 CAR26493.1 - 0.023 14.5 0.4 0.052 13.4 0.3 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIa 60KD_IMP PF02096.15 CAR26494.1 - 3.3e-36 124.8 0.1 3.3e-36 124.8 0.0 1.8 2 0 0 2 2 2 1 60Kd inner membrane protein RhoGAP PF00620.22 CAR26495.1 - 1.7e-37 128.3 1.6 3.6e-37 127.3 0.1 2.3 2 0 0 2 2 2 1 RhoGAP domain RasGEF PF00617.14 CAR26495.1 - 4.4e-23 81.9 3.9 1.5e-22 80.2 0.1 3.2 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.15 CAR26495.1 - 2.1e-16 59.9 0.5 2.1e-16 59.9 0.4 4.5 5 0 0 5 5 5 1 RasGEF N-terminal motif UPF0160 PF03690.8 CAR26496.1 - 8.8e-126 419.6 0.0 1e-125 419.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Cwf_Cwc_15 PF04889.7 CAR26497.1 - 6.9 6.2 8.2 9.9 5.7 5.6 1.4 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sec34 PF04136.10 CAR26498.1 - 1e-22 80.5 4.2 1e-22 80.5 2.9 3.8 4 0 0 4 4 4 1 Sec34-like family Gp-FAR-1 PF05823.7 CAR26498.1 - 5.5e-05 23.1 3.0 0.005 16.8 0.5 2.8 2 0 0 2 2 2 2 Nematode fatty acid retinoid binding protein (Gp-FAR-1) GAT PF03127.9 CAR26498.1 - 0.025 14.5 4.2 0.14 12.1 0.1 3.4 3 0 0 3 3 3 0 GAT domain MCM_N PF14551.1 CAR26498.1 - 1.6 9.2 6.6 8.2 6.9 1.2 3.8 2 2 0 2 2 2 0 MCM N-terminal domain Tbf5 PF06331.7 CAR26499.1 - 3.4e-29 100.4 0.1 3.8e-29 100.2 0.1 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Clathrin PF00637.15 CAR26500.1 - 4.8e-25 87.8 2.1 4.8e-25 87.8 1.5 2.3 2 0 0 2 2 2 1 Region in Clathrin and VPS Vps39_1 PF10366.4 CAR26500.1 - 0.00068 19.6 0.1 0.00068 19.6 0.1 3.2 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 WD40 PF00400.27 CAR26500.1 - 0.0015 18.3 0.1 0.0048 16.7 0.1 1.9 1 0 0 1 1 1 1 WD domain, G-beta repeat Sporozoite_P67 PF05642.6 CAR26500.1 - 4.1 5.1 6.3 5.8 4.6 4.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cwf_Cwc_15 PF04889.7 CAR26500.1 - 6.5 6.3 22.2 13 5.4 15.4 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DDE_1 PF03184.14 CAR26501.1 - 5e-75 251.3 1.1 8.4e-75 250.6 0.2 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 CAR26501.1 - 9.8e-14 50.9 0.1 9.8e-14 50.9 0.0 2.7 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain Transthyretin PF00576.16 CAR26502.1 - 4.4e-30 103.8 0.4 1.2e-20 73.4 0.3 2.3 1 1 1 2 2 2 2 HIUase/Transthyretin family NCD1 PF04904.8 CAR26502.1 - 0.028 14.1 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) Stn1_C PF12659.2 CAR26503.1 - 5e-47 158.8 0.3 8.3e-47 158.1 0.2 1.4 1 0 0 1 1 1 1 Telomere capping C-terminal wHTH Stn1 PF10451.4 CAR26503.1 - 9.6e-43 145.8 0.8 1e-40 139.2 0.1 2.2 1 1 1 2 2 2 2 Telomere regulation protein Stn1 Methyltransf_8 PF05148.10 CAR26504.1 - 8.1e-67 225.0 1.7 2.1e-65 220.4 0.1 2.8 1 1 1 2 2 2 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 CAR26504.1 - 6.9e-08 32.8 0.3 3.2e-07 30.7 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAR26504.1 - 0.00083 18.9 2.3 0.025 14.1 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 CAR26504.1 - 0.015 14.9 0.2 0.12 12.0 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain DUF4407 PF14362.1 CAR26504.1 - 3.9 6.3 5.0 7.3 5.4 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF846 PF05832.7 CAR26505.1 - 2.5e-45 153.6 4.1 3.1e-45 153.3 2.9 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) FA_desaturase PF00487.19 CAR26505.1 - 0.35 10.2 7.7 0.26 10.6 3.6 1.8 1 1 1 2 2 2 0 Fatty acid desaturase DUF3329 PF11808.3 CAR26505.1 - 0.88 9.6 5.6 7.1 6.7 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) CBFD_NFYB_HMF PF00808.18 CAR26507.1 - 2.6e-10 40.2 0.1 4.1e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CLIP PF12032.3 CAR26507.1 - 0.071 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Regulatory CLIP domain of proteinases Ppx-GppA PF02541.11 CAR26507.1 - 0.1 11.7 0.0 0.24 10.5 0.0 1.5 1 1 0 1 1 1 0 Ppx/GppA phosphatase family SecE PF00584.15 CAR26508.1 - 2.1e-10 40.0 0.0 2.3e-10 39.8 0.0 1.0 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Focal_AT PF03623.8 CAR26508.1 - 0.028 13.8 0.0 0.032 13.7 0.0 1.1 1 0 0 1 1 1 0 Focal adhesion targeting region Nop52 PF05997.7 CAR26509.1 - 6.8e-66 221.8 9.1 7.9e-66 221.5 6.3 1.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 Slu7 PF11708.3 CAR26510.1 - 4.5e-42 144.4 15.1 6.4e-42 143.9 10.5 1.2 1 0 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC PF00098.18 CAR26510.1 - 0.00023 20.9 0.2 0.00038 20.2 0.1 1.4 1 0 0 1 1 1 1 Zinc knuckle ProQ PF04352.8 CAR26510.1 - 0.04 13.5 0.1 0.14 11.8 0.1 1.8 1 0 0 1 1 1 0 ProQ/FINO family PrpF PF04303.8 CAR26510.1 - 0.15 10.7 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 PrpF protein SPT2 PF08243.6 CAR26511.1 - 7.5e-30 103.6 28.6 7.5e-30 103.6 19.8 2.7 2 1 1 3 3 3 1 SPT2 chromatin protein Herpes_DNAp_acc PF04929.7 CAR26511.1 - 4.3 6.2 0.0 4.3 6.2 0.0 3.4 1 1 3 4 4 4 0 Herpes DNA replication accessory factor Rad4 PF03835.10 CAR26512.1 - 2.3e-29 101.6 2.1 2.3e-29 101.6 1.5 2.0 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 CAR26512.1 - 1.1e-23 82.7 0.1 2.3e-23 81.6 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 CAR26512.1 - 1.8e-18 65.7 0.2 8.9e-18 63.5 0.0 2.1 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 CAR26512.1 - 1.1e-11 44.8 2.0 3.5e-11 43.2 0.2 2.7 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 CAR26512.1 - 2.2e-05 24.6 0.0 0.00046 20.3 0.0 2.6 2 0 0 2 2 2 1 Transglutaminase-like superfamily Pox_RNA_Pol_19 PF05320.7 CAR26512.1 - 4.1 7.1 12.1 0.26 11.0 0.3 2.7 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit ChaC PF04752.7 CAR26513.1 - 4.6e-55 186.3 0.0 5.9e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein ABC_tran PF00005.22 CAR26514.1 - 2.6e-37 128.1 0.0 2.4e-18 66.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter RLI PF04068.10 CAR26514.1 - 2.9e-15 55.5 5.7 7.5e-15 54.2 3.9 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 CAR26514.1 - 9e-14 52.1 9.2 0.00019 21.4 1.0 4.3 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 CAR26514.1 - 1.6e-10 40.5 2.5 0.0094 15.2 0.0 4.0 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 CAR26514.1 - 1e-09 37.9 1.0 0.086 11.8 0.0 4.4 4 1 0 5 5 5 3 AAA ATPase domain Fer4 PF00037.22 CAR26514.1 - 4.2e-07 29.3 4.0 4.2e-07 29.3 2.8 2.8 3 0 0 3 3 3 1 4Fe-4S binding domain AAA PF00004.24 CAR26514.1 - 5.2e-06 26.6 0.0 0.035 14.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Fer4_6 PF12837.2 CAR26514.1 - 9e-06 25.3 12.2 5.6e-05 22.8 1.8 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain DUF258 PF03193.11 CAR26514.1 - 1.3e-05 24.4 1.6 0.042 13.0 0.0 2.7 3 0 0 3 3 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 CAR26514.1 - 3e-05 24.1 0.0 0.028 14.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 CAR26514.1 - 3.9e-05 23.7 0.0 0.0075 16.2 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 CAR26514.1 - 4.9e-05 22.7 1.1 0.14 11.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CAR26514.1 - 0.00021 22.1 0.1 0.99 10.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain Fer4_7 PF12838.2 CAR26514.1 - 0.00038 20.7 0.6 0.00038 20.7 0.4 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Miro PF08477.8 CAR26514.1 - 0.00066 20.1 0.0 1.8 9.0 0.0 2.9 3 0 0 3 3 2 1 Miro-like protein NB-ARC PF00931.17 CAR26514.1 - 0.00096 18.0 0.0 0.31 9.8 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Fer4_21 PF14697.1 CAR26514.1 - 0.00098 18.9 11.1 0.002 17.9 7.7 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_18 PF13238.1 CAR26514.1 - 0.0014 18.9 0.1 2.5 8.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain NACHT PF05729.7 CAR26514.1 - 0.0016 18.0 1.1 0.23 11.0 0.0 2.5 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.17 CAR26514.1 - 0.0017 18.5 0.0 0.74 10.0 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_25 PF13481.1 CAR26514.1 - 0.0018 17.7 0.0 1.3 8.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4_2 PF12797.2 CAR26514.1 - 0.0019 17.9 12.9 0.0043 16.8 1.7 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_9 PF13187.1 CAR26514.1 - 0.0025 18.0 2.1 0.0025 18.0 1.5 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain MobB PF03205.9 CAR26514.1 - 0.0049 16.5 0.9 0.83 9.3 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 CAR26514.1 - 0.0049 16.8 0.0 1.5 8.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 CAR26514.1 - 0.005 16.7 0.0 4.7 7.1 0.0 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Fer4_16 PF13484.1 CAR26514.1 - 0.005 17.5 0.1 0.005 17.5 0.1 2.5 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain VirE PF05272.6 CAR26514.1 - 0.0061 16.0 0.0 0.95 8.8 0.0 2.4 2 0 0 2 2 2 1 Virulence-associated protein E Fer4_3 PF12798.2 CAR26514.1 - 0.0062 17.0 5.0 0.0062 17.0 3.4 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_10 PF13237.1 CAR26514.1 - 0.0078 15.9 1.4 0.0078 15.9 1.0 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain SRP54 PF00448.17 CAR26514.1 - 0.0078 15.6 2.9 0.32 10.4 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Rad17 PF03215.10 CAR26514.1 - 0.0092 14.7 0.0 0.99 8.0 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_33 PF13671.1 CAR26514.1 - 0.0093 15.8 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 CAR26514.1 - 0.011 15.3 0.3 0.24 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 CAR26514.1 - 0.014 15.0 1.1 0.16 11.6 0.0 2.6 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 CAR26514.1 - 0.015 15.5 3.1 0.13 12.5 0.0 2.5 2 1 0 2 2 2 0 AAA domain UPF0079 PF02367.12 CAR26514.1 - 0.025 14.2 0.3 0.31 10.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_14 PF13173.1 CAR26514.1 - 0.034 14.0 0.5 12 5.8 0.0 3.2 2 1 0 2 2 2 0 AAA domain Fer4_17 PF13534.1 CAR26514.1 - 0.034 14.4 0.2 0.034 14.4 0.1 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain AAA_24 PF13479.1 CAR26514.1 - 0.051 13.1 0.6 0.81 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Fer4_8 PF13183.1 CAR26514.1 - 0.055 13.4 7.9 0.098 12.7 0.9 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain T2SE PF00437.15 CAR26514.1 - 0.066 12.1 0.0 0.23 10.3 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein MMR_HSR1 PF01926.18 CAR26514.1 - 0.092 12.7 0.0 9.9 6.1 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase ArgK PF03308.11 CAR26514.1 - 0.14 10.9 0.2 3.2 6.4 0.0 2.1 2 0 0 2 2 2 0 ArgK protein PduV-EutP PF10662.4 CAR26514.1 - 0.23 10.9 1.6 0.6 9.6 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Fer4_4 PF12800.2 CAR26514.1 - 0.3 11.5 14.2 0.091 13.1 1.7 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain AAA_13 PF13166.1 CAR26514.1 - 0.33 9.3 0.0 0.33 9.3 0.0 2.2 4 0 0 4 4 4 0 AAA domain AAA_19 PF13245.1 CAR26514.1 - 0.33 10.7 1.2 0.95 9.2 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain Fer4_18 PF13746.1 CAR26514.1 - 6.6 7.2 10.5 0.33 11.3 3.0 2.0 1 1 0 2 2 1 0 4Fe-4S dicluster domain SNF2_N PF00176.18 CAR26515.1 - 2.4e-75 253.1 0.1 4.2e-75 252.3 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.1 CAR26515.1 - 1.2e-29 102.5 0.3 1.2e-29 102.5 0.2 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4208) Chromo PF00385.19 CAR26515.1 - 2.1e-22 78.5 5.0 3.1e-13 49.1 0.2 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 CAR26515.1 - 3.8e-16 58.7 0.1 1.7e-15 56.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RRM_1 PF00076.17 CAR26516.1 - 1.6e-81 267.8 4.0 2.4e-20 71.9 0.1 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR26516.1 - 5.7e-58 192.8 0.1 1.4e-15 57.0 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR26516.1 - 3.9e-45 151.4 0.1 1.2e-10 41.0 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 CAR26516.1 - 3.7e-23 80.9 1.5 3.3e-22 77.9 0.0 2.8 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.6 CAR26516.1 - 6.1e-06 26.0 6.6 0.77 9.6 0.0 4.8 4 1 1 5 5 5 3 RNA binding motif CbiG_mid PF11761.3 CAR26516.1 - 0.011 15.9 0.1 1.2 9.3 0.0 2.6 2 0 0 2 2 2 0 Cobalamin biosynthesis central region Nup35_RRM_2 PF14605.1 CAR26516.1 - 0.022 14.4 0.1 2.9 7.7 0.0 3.2 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.6 CAR26516.1 - 0.028 13.9 6.0 1.3 8.6 0.4 3.7 3 1 0 3 3 3 0 Ribonuclease B OB domain TC1 PF15063.1 CAR26516.1 - 0.03 13.8 0.1 0.28 10.7 0.0 2.4 2 0 0 2 2 2 0 Thyroid cancer protein 1 Limkain-b1 PF11608.3 CAR26516.1 - 0.052 13.3 0.4 4.4 7.1 0.0 3.5 4 0 0 4 4 4 0 Limkain b1 UQ_con PF00179.21 CAR26517.1 - 3.4e-47 159.3 0.0 3.9e-47 159.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CAR26517.1 - 0.00011 21.9 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 CAR26517.1 - 0.011 15.4 0.1 0.022 14.4 0.0 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 CAR26517.1 - 0.012 15.4 0.1 0.015 15.1 0.1 1.5 1 1 0 1 1 1 0 RWD domain E1-E2_ATPase PF00122.15 CAR26518.1 - 3.3e-15 55.7 0.8 5.5e-15 55.0 0.0 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 CAR26518.1 - 1.1e-11 44.4 0.0 2.9e-11 43.1 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CAR26518.1 - 1.2e-11 45.1 0.0 3e-11 43.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CAR26518.1 - 2.1e-09 38.1 0.1 2.4e-07 31.3 0.1 3.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CAR26518.1 - 0.0033 17.0 0.1 0.0077 15.8 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PolyA_pol PF01743.15 CAR26520.1 - 1.2e-29 103.0 0.1 2.4e-29 102.1 0.0 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain tRNA_NucTran2_2 PF13735.1 CAR26520.1 - 9.2e-05 22.2 0.0 0.00023 20.9 0.0 1.7 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative PolyA_pol_RNAbd PF12627.2 CAR26520.1 - 0.00023 20.6 0.0 0.00057 19.3 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A JmjC PF02373.17 CAR26521.1 - 2.7e-40 137.1 0.2 2.7e-40 137.1 0.2 2.1 2 0 0 2 2 1 1 JmjC domain, hydroxylase JmjN PF02375.12 CAR26521.1 - 1e-13 50.5 1.2 2.8e-13 49.1 0.8 1.9 1 0 0 1 1 1 1 jmjN domain zf-C2H2 PF00096.21 CAR26521.1 - 8.4e-08 32.1 15.7 0.00027 21.1 1.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CAR26521.1 - 1.4e-07 31.4 5.9 1.4e-07 31.4 4.1 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CAR26521.1 - 5.2e-07 29.5 11.5 0.00052 20.1 0.5 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CAR26521.1 - 0.0082 16.0 9.3 0.012 15.5 2.5 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CAR26521.1 - 0.029 14.5 8.7 0.063 13.4 1.9 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding HypA PF01155.14 CAR26521.1 - 0.071 12.7 0.4 0.16 11.6 0.3 1.5 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-Di19 PF05605.7 CAR26521.1 - 0.69 10.0 3.9 1.5 8.9 2.7 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.5 CAR26521.1 - 0.85 9.6 6.9 4.6 7.2 0.5 2.4 1 1 1 2 2 2 0 Zinc ribbon domain C1_4 PF07975.7 CAR26521.1 - 1.9 8.5 4.4 11 6.1 0.4 2.4 1 1 1 2 2 2 0 TFIIH C1-like domain zf-met PF12874.2 CAR26521.1 - 2.1 8.6 8.4 7.9 6.8 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF1610 PF07754.6 CAR26521.1 - 4 7.6 8.5 1.6 8.9 1.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) MutS_V PF00488.16 CAR26522.1 - 1.6e-76 256.7 0.1 2.8e-76 256.0 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CAR26522.1 - 2.7e-41 141.6 0.2 4.9e-41 140.7 0.2 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 CAR26522.1 - 2.3e-32 111.3 0.0 1.4e-31 108.8 0.0 2.3 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 CAR26522.1 - 1e-18 67.2 0.3 2.3e-18 66.1 0.2 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 CAR26522.1 - 2.8e-13 50.0 0.0 2e-12 47.3 0.0 2.3 2 0 0 2 2 2 1 MutS domain II DUF1564 PF07600.6 CAR26522.1 - 0.0039 16.5 0.0 0.027 13.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1564) AAA_29 PF13555.1 CAR26522.1 - 0.021 14.3 0.0 0.075 12.5 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 CAR26522.1 - 3.1 8.1 6.6 2.7 8.2 0.0 3.0 3 0 0 3 3 3 0 ABC transporter ADK PF00406.17 CAR26523.1 - 1.2e-41 142.0 0.0 1.5e-41 141.8 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 CAR26523.1 - 6e-13 48.2 0.0 9.9e-13 47.5 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 CAR26523.1 - 1.7e-05 24.7 0.0 3.5e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CAR26523.1 - 1.9e-05 24.9 0.0 3.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CAR26523.1 - 0.0021 18.8 0.0 0.0032 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CAR26523.1 - 0.09 11.9 0.1 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF1227 PF06777.6 CAR26524.1 - 4.6e-57 191.8 0.9 4.6e-57 191.8 0.6 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 CAR26524.1 - 2.4e-51 173.6 3.0 2.4e-51 173.6 2.1 1.7 2 0 0 2 2 2 1 DEAD_2 Helicase_C_2 PF13307.1 CAR26524.1 - 8.4e-45 152.7 0.0 3.1e-44 150.8 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD PF00270.24 CAR26524.1 - 0.0027 17.2 0.0 0.7 9.3 0.0 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase SNF2_N PF00176.18 CAR26524.1 - 0.015 14.0 0.2 0.2 10.4 0.2 2.2 1 1 0 1 1 1 0 SNF2 family N-terminal domain ResIII PF04851.10 CAR26524.1 - 0.045 13.5 0.0 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Sec63 PF02889.11 CAR26525.1 - 8.2e-159 527.8 6.5 1.4e-83 280.7 0.2 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 CAR26525.1 - 1.1e-46 158.4 0.1 1.3e-30 106.0 0.0 2.8 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 CAR26525.1 - 1.3e-12 47.9 3.0 4.1e-09 36.5 0.0 3.5 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CAR26525.1 - 1.2e-08 34.7 0.0 4.4e-08 32.8 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CAR26525.1 - 5.5e-05 23.3 0.6 0.11 12.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 CAR26525.1 - 0.00024 20.7 0.0 0.19 11.4 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain IstB_IS21 PF01695.12 CAR26525.1 - 0.0032 16.9 0.0 1.7 8.0 0.0 3.8 4 0 0 4 4 4 1 IstB-like ATP binding protein PhoH PF02562.11 CAR26525.1 - 0.016 14.4 0.0 6.4 5.9 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein AAA PF00004.24 CAR26525.1 - 0.028 14.6 1.2 0.34 11.1 0.0 3.3 4 1 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CAR26526.1 - 3.5e-91 306.4 0.1 4.5e-65 220.3 0.0 2.2 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA PF00004.24 CAR26526.1 - 0.0011 19.1 0.0 0.003 17.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CAR26526.1 - 0.0091 16.8 0.3 0.098 13.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CAR26526.1 - 0.017 15.1 0.0 0.079 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 CAR26526.1 - 0.091 12.9 0.0 0.27 11.4 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Glutaredoxin PF00462.19 CAR26527.1 - 2.6e-18 65.7 0.2 3.9e-17 61.9 0.0 2.5 3 0 0 3 3 3 1 Glutaredoxin Thioredoxin PF00085.15 CAR26527.1 - 1.1e-14 53.9 0.0 2.2e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CAR26527.1 - 1.6e-06 28.1 0.0 0.00021 21.3 0.0 2.5 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.1 CAR26527.1 - 0.0011 18.9 0.1 0.0075 16.2 0.0 2.1 2 1 0 2 2 2 1 Thioredoxin-like TraF PF13728.1 CAR26527.1 - 0.0011 18.4 0.1 1.2 8.5 0.0 2.1 2 0 0 2 2 2 2 F plasmid transfer operon protein Thioredoxin_2 PF13098.1 CAR26527.1 - 0.0043 17.2 0.1 0.058 13.6 0.0 2.6 1 1 1 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.16 CAR26527.1 - 0.008 15.8 0.1 0.014 15.0 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family ArsC PF03960.10 CAR26527.1 - 0.025 14.6 0.0 0.13 12.3 0.0 2.1 2 1 0 2 2 2 0 ArsC family DIM1 PF02966.11 CAR26527.1 - 0.039 13.4 0.0 0.062 12.8 0.0 1.3 1 0 0 1 1 1 0 Mitosis protein DIM1 Methyltransf_11 PF08241.7 CAR26528.1 - 3.7e-13 49.7 0.0 6.1e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAR26528.1 - 3.9e-12 46.0 0.0 6.5e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAR26528.1 - 1.2e-10 41.6 0.0 2.4e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR26528.1 - 5.5e-10 39.8 0.0 9.5e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAR26528.1 - 1.1e-09 38.6 0.0 1.8e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAR26528.1 - 1.2e-09 38.0 0.0 1.7e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CAR26528.1 - 7.4e-06 25.2 0.0 1.1e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 CAR26528.1 - 0.00024 21.1 0.0 0.0021 18.0 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 CAR26528.1 - 0.00043 20.3 0.0 0.00073 19.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.1 CAR26528.1 - 0.00068 19.3 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CAR26528.1 - 0.0027 16.8 0.0 0.0037 16.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 CAR26528.1 - 0.032 13.7 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 CAR26528.1 - 0.062 12.6 0.0 0.15 11.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain Rsm22 PF09243.5 CAR26528.1 - 0.09 11.7 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_31 PF13847.1 CAR26529.1 - 5.4e-13 48.8 0.0 7.9e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CAR26529.1 - 2.4e-11 43.9 0.0 4.3e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAR26529.1 - 2e-09 37.8 0.0 5.3e-09 36.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAR26529.1 - 5.2e-09 36.3 0.0 9.6e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR26529.1 - 6.6e-08 33.1 0.0 1.2e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAR26529.1 - 6.7e-07 29.1 0.0 9.7e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CAR26529.1 - 1.4e-05 24.2 0.0 2.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 CAR26529.1 - 0.021 13.8 0.0 0.037 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 CAR26529.1 - 0.028 13.7 0.0 0.097 12.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_26 PF13659.1 CAR26529.1 - 0.029 14.3 0.0 0.2 11.7 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 CAR26529.1 - 0.045 12.7 0.0 0.087 11.7 0.0 1.5 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family PrmA PF06325.8 CAR26529.1 - 0.066 12.3 0.0 0.09 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 CAR26529.1 - 0.096 12.3 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain AAA_12 PF13087.1 CAR26530.1 - 1.9e-56 190.5 0.0 6.4e-56 188.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 CAR26530.1 - 2.1e-44 151.8 1.0 2.1e-44 151.8 0.7 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CAR26530.1 - 3.1e-10 39.6 0.0 2.8e-09 36.5 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 CAR26530.1 - 5.3e-10 39.2 0.0 8.7e-09 35.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 CAR26530.1 - 2.2e-06 27.3 0.0 0.028 13.9 0.0 3.6 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 CAR26530.1 - 0.00033 20.1 0.1 0.00099 18.6 0.0 1.8 1 1 1 2 2 2 1 DEAD/DEAH box helicase UvrD-helicase PF00580.16 CAR26530.1 - 0.00078 18.8 0.1 0.00078 18.8 0.1 2.7 2 2 0 2 2 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 CAR26530.1 - 0.0012 18.9 0.0 0.072 13.2 0.0 2.6 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain DUF258 PF03193.11 CAR26530.1 - 0.0028 16.8 0.3 0.019 14.1 0.2 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF258 PhoH PF02562.11 CAR26530.1 - 0.003 16.8 0.0 0.024 13.8 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein ResIII PF04851.10 CAR26530.1 - 0.0042 16.9 0.1 0.0042 16.9 0.1 2.5 3 1 0 3 3 1 1 Type III restriction enzyme, res subunit AAA PF00004.24 CAR26530.1 - 0.0052 16.9 0.0 0.032 14.4 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CAR26530.1 - 0.011 15.6 0.0 0.039 13.9 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 CAR26530.1 - 0.022 15.0 0.0 0.19 12.0 0.0 2.6 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CAR26530.1 - 0.023 14.4 0.1 0.088 12.4 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase AAA_22 PF13401.1 CAR26530.1 - 0.057 13.5 0.0 0.52 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CAR26530.1 - 0.12 11.8 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain 14-3-3 PF00244.15 CAR26531.1 - 6.3e-114 378.9 5.3 7.4e-114 378.6 3.7 1.0 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.6 CAR26531.1 - 0.026 14.3 0.2 0.082 12.7 0.1 1.8 1 0 0 1 1 1 0 Flagellar protein FlaF SPACA7 PF15307.1 CAR26531.1 - 0.16 12.0 3.1 3.3 7.8 0.1 2.9 2 1 0 2 2 2 0 Sperm acrosome-associated protein 7 COPI_assoc PF08507.5 CAR26532.1 - 1e-34 119.2 5.7 1.2e-34 118.9 4.0 1.0 1 0 0 1 1 1 1 COPI associated protein Peptidase_M24 PF00557.19 CAR26533.1 - 1e-11 44.8 0.0 1.4e-10 41.1 0.0 2.2 2 0 0 2 2 2 1 Metallopeptidase family M24 CRAL_TRIO PF00650.15 CAR26534.1 - 1.8e-39 134.7 0.0 2.9e-39 134.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CAR26534.1 - 6.6e-10 38.9 2.9 7e-10 38.9 0.2 2.5 2 1 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 CAR26534.1 - 3.7e-09 36.6 0.0 6.1e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Peptidase_A17 PF05380.8 CAR26534.1 - 0.043 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Pao retrotransposon peptidase tRNA-synt_1 PF00133.17 CAR26536.1 - 3.3e-60 203.7 0.3 4.5e-18 64.5 0.1 6.1 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 CAR26536.1 - 9e-46 155.4 0.0 1.5e-45 154.7 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 CAR26536.1 - 2e-29 102.4 0.1 2.8e-21 75.6 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 CAR26536.1 - 1e-06 28.5 0.2 2.3e-06 27.4 0.2 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 CAR26536.1 - 4.2e-06 26.0 0.0 0.084 11.9 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 CAR26536.1 - 5.4e-06 25.4 0.0 1.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (R) SMC_N PF02463.14 CAR26537.1 - 2.8e-24 85.5 13.1 2.2e-23 82.6 9.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CAR26537.1 - 2.9e-09 37.5 35.4 2.9e-09 37.5 24.6 5.2 2 2 0 2 2 1 1 AAA domain AAA_21 PF13304.1 CAR26537.1 - 1.7e-05 24.9 17.9 0.013 15.4 0.7 3.8 2 2 0 2 2 2 2 AAA domain WEMBL PF05701.6 CAR26537.1 - 2e-05 23.2 13.4 2e-05 23.2 9.3 3.2 2 1 1 3 3 3 1 Weak chloroplast movement under blue light AAA_29 PF13555.1 CAR26537.1 - 8.3e-05 22.0 0.0 0.00022 20.6 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_hinge PF06470.8 CAR26537.1 - 0.0001 22.2 0.4 0.0035 17.3 0.0 3.1 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain HsbA PF12296.3 CAR26537.1 - 0.00036 20.3 1.1 0.0088 15.9 0.0 3.8 3 1 0 3 3 3 1 Hydrophobic surface binding protein A DUF869 PF05911.6 CAR26537.1 - 0.0049 15.1 48.7 0.0037 15.5 6.5 2.4 2 0 0 2 2 2 2 Plant protein of unknown function (DUF869) AAA_13 PF13166.1 CAR26537.1 - 0.021 13.3 66.7 0.026 13.0 10.9 5.0 3 2 2 5 5 5 0 AAA domain ABC_tran PF00005.22 CAR26537.1 - 0.075 13.3 0.1 0.075 13.3 0.0 5.2 3 2 0 3 3 2 0 ABC transporter Reo_sigmaC PF04582.7 CAR26537.1 - 0.13 11.3 17.7 1.4 8.0 0.2 4.3 2 2 1 4 4 4 0 Reovirus sigma C capsid protein Uso1_p115_head PF04869.9 CAR26538.1 - 1.1e-106 356.1 0.1 1.1e-106 356.1 0.1 2.6 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 CAR26538.1 - 6.3e-11 42.3 34.1 6.3e-11 42.3 23.6 14.9 1 1 14 15 15 15 1 Uso1 / p115 like vesicle tethering protein, C terminal region Myosin_tail_1 PF01576.14 CAR26538.1 - 4.2e-08 31.4 341.2 1.7e-05 22.7 40.5 5.1 1 1 4 5 5 5 4 Myosin tail Filament PF00038.16 CAR26538.1 - 0.0021 17.5 49.1 0.0021 17.5 34.0 8.2 1 1 5 6 6 6 5 Intermediate filament protein Reo_sigmaC PF04582.7 CAR26538.1 - 0.0074 15.5 127.0 0.084 12.0 2.3 11.5 1 1 10 12 12 12 9 Reovirus sigma C capsid protein IncA PF04156.9 CAR26538.1 - 0.092 12.3 319.3 0.0089 15.6 13.9 13.9 1 1 9 10 10 10 0 IncA protein AAA_13 PF13166.1 CAR26538.1 - 9.6 4.5 291.9 0.0036 15.8 26.2 8.2 1 1 7 8 8 8 0 AAA domain Rad52_Rad22 PF04098.10 CAR26539.1 - 4.1e-37 127.2 0.0 4.8e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein IKI3 PF04762.7 CAR26540.1 - 0 1100.6 0.5 0 1100.3 0.4 1.1 1 0 0 1 1 1 1 IKI3 family PPR_1 PF12854.2 CAR26540.1 - 0.022 14.2 0.1 0.087 12.3 0.0 2.0 1 0 0 1 1 1 0 PPR repeat Vac14_Fig4_bd PF11916.3 CAR26542.1 - 4.1e-71 237.8 4.9 4.1e-71 237.8 3.4 2.0 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 CAR26542.1 - 5.6e-48 161.3 2.0 7.3e-39 132.0 0.0 4.5 4 0 0 4 4 4 3 Vacuolar 14 Fab1-binding region HEAT PF02985.17 CAR26542.1 - 2.2e-11 42.8 9.5 0.00024 20.9 0.0 7.4 7 0 0 7 7 7 1 HEAT repeat Cnd1 PF12717.2 CAR26542.1 - 1.7e-08 34.4 5.8 0.0034 17.2 0.4 3.7 3 0 0 3 3 3 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CAR26542.1 - 2.4e-08 34.1 4.7 0.006 16.8 0.0 5.0 5 0 0 5 5 5 3 HEAT repeats CLASP_N PF12348.3 CAR26542.1 - 1.6e-07 30.9 1.2 0.0015 17.9 0.3 4.0 3 1 1 4 4 4 2 CLASP N terminal HEAT_EZ PF13513.1 CAR26542.1 - 7.1e-07 29.5 9.3 0.075 13.5 0.0 6.7 6 1 3 9 9 9 2 HEAT-like repeat ParcG PF10274.4 CAR26542.1 - 0.0051 16.7 0.5 3.2 7.6 0.0 2.7 2 0 0 2 2 2 2 Parkin co-regulated protein Arm PF00514.18 CAR26542.1 - 0.0051 16.5 7.7 2.9 7.8 0.0 5.4 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Sigma70_r2 PF04542.9 CAR26542.1 - 0.15 11.7 0.1 6.5 6.4 0.2 2.5 2 0 0 2 2 2 0 Sigma-70 region 2 RasGEF_N_2 PF14663.1 CAR26542.1 - 0.44 10.5 5.9 0.35 10.8 0.1 3.3 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain zf-C2H2_2 PF12756.2 CAR26543.1 - 2.6e-31 107.7 5.5 4.2e-29 100.6 1.5 2.6 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 CAR26543.1 - 0.023 14.8 0.6 0.023 14.8 0.4 3.8 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding Consortin_C PF15281.1 CAR26543.1 - 6.5 6.2 6.0 2.8 7.4 0.7 2.5 2 0 0 2 2 2 0 Consortin C-terminus DUF663 PF04950.7 CAR26544.1 - 5.7e-96 320.9 0.0 1.2e-95 319.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 CAR26544.1 - 4.7e-26 90.1 0.0 1.1e-25 88.9 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Ribosomal_S14 PF00253.16 CAR26545.1 - 4.1e-19 67.6 3.6 4.5e-19 67.5 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.1 CAR26545.1 - 0.024 14.3 0.4 0.028 14.1 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Cytochrom_CIII PF02085.11 CAR26545.1 - 0.067 13.2 0.8 0.066 13.3 0.5 1.1 1 0 0 1 1 1 0 Class III cytochrome C family Prim_Zn_Ribbon PF08273.7 CAR26545.1 - 0.29 11.2 2.3 5.4 7.1 0.2 2.1 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Peptidase_M16 PF00675.15 CAR26546.1 - 5.8e-39 133.2 0.1 2.1e-38 131.4 0.1 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CAR26546.1 - 3.9e-32 111.4 1.2 9.6e-18 64.4 0.0 3.5 3 0 0 3 3 3 3 Peptidase M16 inactive domain Cathelicidins PF00666.12 CAR26546.1 - 0.087 12.9 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 Cathelicidin nsp7 PF08716.5 CAR26547.1 - 0.0021 18.3 0.3 0.022 15.1 0.1 2.9 2 1 0 2 2 2 1 nsp7 replicase Arm PF00514.18 CAR26547.1 - 0.078 12.8 0.6 3.7 7.5 0.0 3.4 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat RhoGAP PF00620.22 CAR26547.1 - 0.12 11.9 1.7 0.31 10.6 0.2 2.4 3 0 0 3 3 3 0 RhoGAP domain UQ_con PF00179.21 CAR26548.1 - 8e-44 148.4 0.0 9.1e-44 148.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CAR26548.1 - 0.00022 20.9 0.0 0.00026 20.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CAR26548.1 - 0.45 10.4 2.6 0.67 9.8 1.8 1.6 1 1 0 1 1 1 0 RWD domain Pex19 PF04614.7 CAR26549.1 - 1e-54 185.8 17.6 1e-54 185.8 12.2 1.8 1 1 1 2 2 2 1 Pex19 protein family CFEM PF05730.6 CAR26550.1 - 4.1e-08 32.9 10.2 9.5e-08 31.7 7.0 1.7 1 0 0 1 1 1 1 CFEM domain DUF605 PF04652.11 CAR26550.1 - 0.75 9.1 11.5 0.82 9.0 8.0 1.1 1 0 0 1 1 1 0 Vta1 like Arrestin_N PF00339.24 CAR26551.1 - 3.3e-06 27.0 0.2 2.2e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain ATP-synt_10 PF05176.9 CAR26552.1 - 6.4e-82 274.6 0.0 8e-82 274.3 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein Iso_dh PF00180.15 CAR26553.1 - 5.9e-68 229.3 0.0 6.8e-68 229.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF925 PF06042.6 CAR26553.1 - 0.12 11.9 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF925) zf-RING_5 PF14634.1 CAR26554.1 - 4.3e-08 32.7 10.6 9.6e-08 31.6 7.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CAR26554.1 - 0.0087 16.0 5.6 0.027 14.4 3.9 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FliJ PF02050.11 CAR26554.1 - 0.053 13.5 3.2 0.16 12.0 2.2 1.9 1 0 0 1 1 1 0 Flagellar FliJ protein zf-RING_UBOX PF13445.1 CAR26554.1 - 6.2 6.6 11.4 0.12 12.1 2.0 2.6 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.1 CAR26554.1 - 6.2 6.7 10.5 26 4.7 7.3 2.0 1 1 0 1 1 1 0 Ring finger domain COX7C PF02935.11 CAR26555.1 - 3.2e-20 71.6 1.7 3.5e-20 71.5 1.2 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc STE PF02200.11 CAR26555.1 - 0.045 13.9 0.2 0.076 13.1 0.1 1.5 1 1 0 1 1 1 0 STE like transcription factor Sec1 PF00995.18 CAR26557.1 - 4e-66 223.8 4.4 1.3e-65 222.1 3.0 1.7 1 1 0 1 1 1 1 Sec1 family AAA PF00004.24 CAR26558.1 - 2.5e-89 296.2 0.0 4.9e-44 149.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CAR26558.1 - 2e-13 49.9 0.0 8.2e-06 25.0 0.0 3.2 3 1 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CAR26558.1 - 3.8e-11 43.3 0.1 1.8e-05 24.8 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 CAR26558.1 - 5.2e-11 42.4 0.1 0.00014 21.6 0.0 3.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CAR26558.1 - 1.9e-10 40.9 0.0 0.00029 20.7 0.0 3.5 3 1 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CAR26558.1 - 2.7e-10 40.5 0.7 0.00012 22.2 0.0 4.4 2 2 0 2 2 2 2 AAA domain AAA_14 PF13173.1 CAR26558.1 - 1e-08 35.1 0.0 0.00016 21.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 CAR26558.1 - 3.8e-07 30.0 0.0 0.00032 20.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 CAR26558.1 - 8.7e-07 27.9 0.0 0.0074 15.0 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus CDC48_N PF02359.13 CAR26558.1 - 1.3e-06 28.2 0.0 4.2e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_17 PF13207.1 CAR26558.1 - 3.2e-06 27.9 0.0 0.021 15.6 0.0 2.8 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 CAR26558.1 - 9.4e-06 25.7 0.0 0.25 11.5 0.0 3.1 3 0 0 3 3 2 2 RNA helicase Mg_chelatase PF01078.16 CAR26558.1 - 1.9e-05 23.9 0.2 0.053 12.6 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 CAR26558.1 - 3.1e-05 23.1 0.0 0.11 11.6 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_28 PF13521.1 CAR26558.1 - 0.00011 22.1 0.0 0.24 11.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.1 CAR26558.1 - 0.00012 22.1 0.0 0.044 13.8 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Bac_DnaA PF00308.13 CAR26558.1 - 0.00035 20.3 0.0 0.0084 15.7 0.0 2.8 3 1 0 3 3 2 1 Bacterial dnaA protein NACHT PF05729.7 CAR26558.1 - 0.00036 20.2 0.2 0.066 12.8 0.0 3.5 4 0 0 4 4 4 1 NACHT domain AAA_25 PF13481.1 CAR26558.1 - 0.0004 19.8 6.3 1.3 8.4 0.1 4.0 2 2 1 4 4 4 2 AAA domain AAA_3 PF07726.6 CAR26558.1 - 0.00049 19.6 0.0 0.55 9.8 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 CAR26558.1 - 0.00087 19.0 0.0 3.6 7.2 0.0 3.3 2 2 1 3 3 3 1 Archaeal ATPase AAA_19 PF13245.1 CAR26558.1 - 0.00088 18.9 8.4 0.0043 16.7 0.2 3.7 5 0 0 5 5 3 1 Part of AAA domain IstB_IS21 PF01695.12 CAR26558.1 - 0.0025 17.2 0.8 2 7.7 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein Rad17 PF03215.10 CAR26558.1 - 0.0027 16.4 0.0 0.032 12.9 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_18 PF13238.1 CAR26558.1 - 0.003 17.8 0.1 0.17 12.1 0.1 2.8 2 1 0 2 2 2 1 AAA domain AFG1_ATPase PF03969.11 CAR26558.1 - 0.0051 15.6 0.0 0.24 10.1 0.0 2.4 2 0 0 2 2 2 1 AFG1-like ATPase Viral_helicase1 PF01443.13 CAR26558.1 - 0.0061 16.1 0.0 0.036 13.5 0.0 2.2 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 CAR26558.1 - 0.0065 16.7 0.0 0.29 11.4 0.0 2.8 2 1 0 2 2 2 1 ABC transporter AAA_11 PF13086.1 CAR26558.1 - 0.011 15.2 0.1 0.68 9.4 0.0 2.6 1 1 0 2 2 2 0 AAA domain UPF0079 PF02367.12 CAR26558.1 - 0.025 14.1 0.2 1.3 8.7 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 CAR26558.1 - 0.028 13.9 0.2 5.3 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 CAR26558.1 - 0.044 12.9 0.1 14 4.7 0.0 3.1 3 0 0 3 3 3 0 KaiC Sigma54_activat PF00158.21 CAR26558.1 - 0.047 13.1 0.0 17 4.7 0.0 3.3 3 1 0 3 3 3 0 Sigma-54 interaction domain Trigger_C PF05698.9 CAR26558.1 - 0.054 13.3 0.4 1.9 8.3 0.4 2.3 2 0 0 2 2 2 0 Bacterial trigger factor protein (TF) C-terminus DUF815 PF05673.8 CAR26558.1 - 0.094 11.6 0.0 2.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_30 PF13604.1 CAR26558.1 - 0.16 11.5 1.1 0.63 9.5 0.0 2.5 4 0 0 4 4 3 0 AAA domain Ribonucleas_3_3 PF14622.1 CAR26559.1 - 0.0012 18.8 0.0 0.0031 17.4 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease-III-like gag_pre-integrs PF13976.1 CAR26559.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 GAG-pre-integrase domain DSHCT PF08148.7 CAR26560.1 - 5.6e-58 195.1 0.3 1.2e-57 194.0 0.2 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 CAR26560.1 - 7.5e-22 77.6 1.2 2e-21 76.2 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.1 CAR26560.1 - 7.6e-09 35.1 0.5 1.9e-08 33.8 0.3 1.7 1 0 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.26 CAR26560.1 - 6.5e-08 32.3 0.0 2.1e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAR26560.1 - 0.003 17.3 1.0 0.013 15.3 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Toxin-deaminase PF14424.1 CAR26560.1 - 0.012 15.6 0.7 0.17 11.8 0.0 2.6 2 0 0 2 2 2 0 The BURPS668_1122 family of deaminases Bromodomain PF00439.20 CAR26561.1 - 9.9e-43 143.9 1.3 8.5e-21 73.6 0.0 2.5 2 0 0 2 2 2 2 Bromodomain Bap31 PF05529.7 CAR26562.1 - 8.5e-53 178.6 1.7 9.9e-53 178.4 1.2 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like DUF2383 PF09537.5 CAR26562.1 - 0.0056 16.9 0.8 0.0082 16.3 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2383) DUF3661 PF12400.3 CAR26562.1 - 0.0069 16.4 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 Vaculolar membrane protein BofA PF07441.6 CAR26562.1 - 0.0099 15.8 1.0 0.042 13.8 0.1 2.1 2 0 0 2 2 2 1 SigmaK-factor processing regulatory protein BofA IFT20 PF14931.1 CAR26562.1 - 0.019 14.8 5.0 0.019 14.8 3.5 1.5 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 Vfa1 PF08432.5 CAR26562.1 - 0.11 12.5 2.9 0.17 11.8 2.0 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DivIC PF04977.10 CAR26562.1 - 0.28 10.6 8.0 7.3 6.1 4.2 2.7 3 0 0 3 3 3 0 Septum formation initiator Synaptobrevin PF00957.16 CAR26562.1 - 5.3 6.7 5.5 1.5 8.4 0.4 2.4 2 1 0 2 2 2 0 Synaptobrevin Dus PF01207.12 CAR26563.1 - 5.6e-43 146.9 0.0 6.8e-42 143.3 0.0 2.2 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 CAR26563.1 - 0.0009 18.8 10.3 0.0017 17.9 0.5 2.8 2 1 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C2H2_4 PF13894.1 CAR26564.1 - 4.6e-05 23.4 12.1 0.057 13.7 0.3 4.0 3 0 0 3 3 3 2 C2H2-type zinc finger BSP_II PF05432.6 CAR26564.1 - 0.00011 21.6 2.3 0.00025 20.4 1.6 1.7 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) zf-C2H2 PF00096.21 CAR26564.1 - 0.0016 18.6 17.1 0.073 13.4 0.7 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CAR26564.1 - 0.046 14.0 1.1 0.046 14.0 0.8 3.8 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CAR26564.1 - 0.15 12.2 0.1 0.15 12.2 0.0 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding YL1 PF05764.8 CAR26564.1 - 1.1 8.8 12.0 0.16 11.5 1.0 2.3 2 0 0 2 2 2 0 YL1 nuclear protein TRAP_alpha PF03896.11 CAR26564.1 - 1.4 7.8 4.7 2.6 6.9 3.3 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nucleoplasmin PF03066.10 CAR26564.1 - 8.7 5.8 15.1 22 4.5 10.5 1.6 1 0 0 1 1 1 0 Nucleoplasmin DUF1765 PF08578.5 CAR26566.1 - 2.1e-23 82.7 7.7 2.1e-23 82.7 5.3 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1765) BRE1 PF08647.6 CAR26567.1 - 9.9e-31 105.5 10.4 9.9e-31 105.5 7.2 5.6 4 1 0 5 5 4 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 CAR26567.1 - 6.4e-07 29.2 14.2 1.4e-06 28.1 9.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CAR26567.1 - 1.8e-06 27.4 12.0 4.3e-06 26.3 8.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAR26567.1 - 1e-05 25.1 13.9 2.5e-05 23.9 9.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CAR26567.1 - 4.3e-05 23.0 14.5 0.00014 21.4 10.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CAR26567.1 - 0.00024 20.8 11.3 0.00063 19.5 7.8 1.8 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.7 CAR26567.1 - 0.00034 19.9 3.3 0.00034 19.9 2.3 4.7 3 1 3 6 6 3 1 Rtf2 RING-finger Prok-RING_4 PF14447.1 CAR26567.1 - 0.0061 16.0 4.8 0.016 14.6 3.3 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C2H2 PF00096.21 CAR26567.1 - 0.0095 16.2 0.2 0.0095 16.2 0.1 3.0 3 0 0 3 3 2 1 Zinc finger, C2H2 type IncA PF04156.9 CAR26567.1 - 0.012 15.1 5.9 0.012 15.1 4.1 5.4 2 1 3 5 5 5 0 IncA protein zf-RING_6 PF14835.1 CAR26567.1 - 0.016 14.9 4.8 0.039 13.7 3.3 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 CAR26567.1 - 0.43 10.3 12.7 0.19 11.4 6.1 2.6 2 0 0 2 2 2 0 RING-type zinc-finger DUF2353 PF09789.4 CAR26567.1 - 1.6 7.8 61.1 0.061 12.5 9.7 4.6 1 1 4 5 5 5 0 Uncharacterized coiled-coil protein (DUF2353) zf-RING_4 PF14570.1 CAR26567.1 - 2 8.0 11.5 4.8 6.8 7.9 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 CAR26567.1 - 4.6 7.2 11.1 13 5.8 7.7 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Myosin_tail_1 PF01576.14 CAR26567.1 - 7.1 4.2 68.0 0.21 9.2 34.5 3.1 2 1 1 3 3 3 0 Myosin tail Dus PF01207.12 CAR26568.1 - 6.5e-78 261.6 0.0 7.9e-78 261.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) IMPDH PF00478.20 CAR26568.1 - 0.009 14.9 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain RHIM PF12721.2 CAR26568.1 - 0.18 12.2 0.4 0.39 11.1 0.3 1.6 1 0 0 1 1 1 0 RIP homotypic interaction motif Ribosomal_L31e PF01198.14 CAR26569.1 - 1.7e-33 114.1 1.8 2e-33 113.8 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Rxt3 PF08642.5 CAR26570.1 - 2e-30 105.3 0.0 6.2e-30 103.7 0.0 1.8 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 DUF4050 PF13259.1 CAR26571.1 - 2.5e-22 79.0 0.3 4.1e-22 78.3 0.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4050) FXR1P_C PF12235.3 CAR26571.1 - 0.066 13.3 2.1 0.086 12.9 1.5 1.4 1 0 0 1 1 1 0 Fragile X-related 1 protein C terminal GCN5L1 PF06320.8 CAR26572.1 - 0.008 15.9 0.2 0.01 15.6 0.1 1.4 1 1 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) DNA_topoisoIV PF00521.15 CAR26572.1 - 0.083 11.7 0.5 0.088 11.6 0.3 1.0 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Vps39_1 PF10366.4 CAR26573.1 - 5.3e-28 97.1 0.2 5.3e-28 97.1 0.1 3.5 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 CAR26573.1 - 6.4e-15 55.2 0.1 2.1e-14 53.5 0.1 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 DUF2175 PF09943.4 CAR26573.1 - 0.00013 21.9 0.9 0.00037 20.4 0.6 1.8 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2175) Utp21 PF04192.7 CAR26574.1 - 1.7e-75 253.2 0.4 2.3e-75 252.7 0.3 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 CAR26574.1 - 3.8e-22 77.2 8.4 4.3e-10 39.0 0.2 7.7 8 0 0 8 8 8 3 WD domain, G-beta repeat PQQ_2 PF13360.1 CAR26574.1 - 4.1e-06 26.4 0.0 0.017 14.6 0.0 3.6 2 1 1 3 3 3 2 PQQ-like domain Apc4_WD40 PF12894.2 CAR26574.1 - 6.8e-06 25.5 0.0 0.5 9.9 0.0 4.2 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.11 CAR26574.1 - 8.1e-05 21.0 0.0 0.00028 19.3 0.0 1.8 2 0 0 2 2 2 1 Cytochrome D1 heme domain eIF2A PF08662.6 CAR26574.1 - 0.0011 18.6 0.2 0.06 13.0 0.0 3.4 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A CPSF_A PF03178.10 CAR26574.1 - 0.0011 18.0 0.5 0.81 8.7 0.0 3.4 3 1 1 4 4 4 2 CPSF A subunit region SGL PF08450.7 CAR26574.1 - 0.002 17.5 0.2 16 4.7 0.0 4.8 5 1 1 6 6 6 0 SMP-30/Gluconolaconase/LRE-like region Nucleoporin_N PF08801.6 CAR26574.1 - 0.016 13.9 0.1 1.9 7.1 0.0 3.5 2 1 0 3 3 3 0 Nup133 N terminal like Nup160 PF11715.3 CAR26574.1 - 0.053 11.6 0.0 0.099 10.7 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 His_Phos_2 PF00328.17 CAR26575.1 - 2.3e-129 431.7 0.6 4.2e-129 430.8 0.4 1.5 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 CAR26575.1 - 4.3e-09 36.1 0.0 1e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 CAR26575.1 - 0.0073 16.1 1.1 0.02 14.7 0.2 2.3 2 1 0 2 2 2 1 ATP-grasp domain Pribosyltran_N PF13793.1 CAR26576.1 - 3.1e-39 133.2 0.1 1.3e-38 131.2 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 CAR26576.1 - 1.1e-37 129.5 2.0 3.9e-30 104.9 0.3 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 CAR26576.1 - 4.4e-06 26.4 0.1 0.00012 21.7 0.1 2.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain SRR1 PF07985.7 CAR26577.1 - 2.4e-17 62.5 0.0 4.3e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 SRR1 Acyl_transf_1 PF00698.16 CAR26578.1 - 4.1e-95 318.7 0.0 5.4e-94 315.0 0.0 2.5 2 0 0 2 2 2 1 Acyl transferase domain MaoC_dehydratas PF01575.14 CAR26578.1 - 2.4e-37 127.0 0.0 5.6e-37 125.8 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 CAR26578.1 - 5.5e-30 102.9 0.0 1.4e-29 101.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 CAR26578.1 - 7.5e-16 58.1 0.0 2.6e-15 56.3 0.0 1.9 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.10 CAR26578.1 - 2.7e-05 23.4 0.0 0.00024 20.3 0.0 2.4 1 1 0 1 1 1 1 Nitronate monooxygenase Lipase_3 PF01764.20 CAR26578.1 - 0.055 13.0 0.4 2.7 7.5 0.0 2.9 2 0 0 2 2 2 0 Lipase (class 3) Voldacs PF03517.8 CAR26579.1 - 9.8e-17 61.0 0.1 1.3e-16 60.6 0.1 1.1 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Orn_Arg_deC_N PF02784.11 CAR26580.1 - 3.2e-76 255.8 0.0 4.1e-76 255.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 CAR26580.1 - 3.2e-28 97.7 0.0 5.5e-28 97.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.19 CAR26580.1 - 0.089 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel GATA PF00320.22 CAR26581.1 - 3.2e-10 39.1 9.3 3.2e-10 39.1 6.4 2.4 3 0 0 3 3 3 1 GATA zinc finger BAF1_ABF1 PF04684.8 CAR26581.1 - 1.9 7.2 22.0 2.9 6.6 15.2 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PAT1 PF09770.4 CAR26581.1 - 7.1 4.7 23.9 0.31 9.2 12.0 1.9 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Mtr2 PF10429.4 CAR26582.1 - 3e-68 228.7 0.1 3.5e-68 228.5 0.1 1.0 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 NTF2 PF02136.15 CAR26582.1 - 0.014 15.7 0.0 0.023 15.0 0.0 1.4 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain SUR7 PF06687.7 CAR26583.1 - 4.3e-38 130.9 12.6 5e-38 130.7 8.8 1.0 1 0 0 1 1 1 1 SUR7/PalI family DUF2723 PF11028.3 CAR26583.1 - 0.048 13.1 0.3 0.048 13.1 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2723) ABC_membrane_2 PF06472.10 CAR26585.1 - 3.3e-73 246.2 10.1 4.5e-73 245.8 7.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 CAR26585.1 - 6.1e-18 65.4 0.0 1.7e-17 63.9 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 CAR26585.1 - 1.6e-05 25.0 0.1 0.00027 20.9 0.0 2.9 4 0 0 4 4 4 1 AAA domain AAA_23 PF13476.1 CAR26585.1 - 0.0023 18.2 0.3 0.0089 16.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CAR26585.1 - 0.019 14.4 0.0 0.047 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PBP1_TM PF14812.1 CAR26585.1 - 0.022 15.0 0.4 0.047 14.0 0.3 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF258 PF03193.11 CAR26585.1 - 0.025 13.7 0.0 0.06 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SMC_N PF02463.14 CAR26585.1 - 0.045 12.9 0.0 0.15 11.2 0.0 1.9 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CAR26585.1 - 0.071 13.0 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain EAP30 PF04157.11 CAR26586.1 - 2.8e-39 134.5 0.0 5.6e-39 133.5 0.0 1.5 1 1 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 CAR26586.1 - 1.4e-30 104.9 0.2 3.4e-30 103.6 0.2 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Cas_CXXC_CXXC PF09706.5 CAR26586.1 - 0.021 14.9 1.2 0.021 14.9 0.8 3.0 2 1 1 3 3 3 0 CRISPR-associated protein (Cas_CXXC_CXXC) zf-Sec23_Sec24 PF04810.10 CAR26586.1 - 0.03 13.8 0.2 0.03 13.8 0.1 2.8 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger GRAM PF02893.15 CAR26586.1 - 0.05 13.1 0.0 0.24 10.9 0.0 2.2 2 0 0 2 2 2 0 GRAM domain DZR PF12773.2 CAR26586.1 - 2.8 7.8 11.0 0.13 12.0 0.5 2.5 2 1 0 2 2 2 0 Double zinc ribbon zf-RanBP PF00641.13 CAR26586.1 - 4.5 6.4 14.0 0.2 10.7 0.6 2.8 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others Mo25 PF08569.6 CAR26587.1 - 1.3e-117 392.5 14.9 1.5e-117 392.3 10.3 1.0 1 0 0 1 1 1 1 Mo25-like DUF1436 PF07262.6 CAR26587.1 - 0.0028 17.1 1.1 0.0053 16.2 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1436) CDC73 PF05179.9 CAR26588.1 - 8.3e-69 231.9 0.3 1.2e-68 231.4 0.2 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family Exonuc_VIII PF06630.6 CAR26588.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Enterobacterial exodeoxyribonuclease VIII OB_NTP_bind PF07717.11 CAR26589.1 - 7.9e-20 70.8 0.1 2.6e-19 69.1 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold RWD PF05773.17 CAR26589.1 - 9.6e-11 41.5 0.1 4.2e-10 39.5 0.1 2.2 1 0 0 1 1 1 1 RWD domain DEAD PF00270.24 CAR26589.1 - 1.3e-10 41.0 1.3 3.9e-10 39.4 0.4 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR26589.1 - 2.2e-10 40.2 0.1 5.4e-10 38.9 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.18 CAR26589.1 - 5.4e-09 35.9 0.1 5.4e-09 35.9 0.0 2.8 3 0 0 3 3 3 1 Helicase associated domain (HA2) AAA_22 PF13401.1 CAR26589.1 - 0.00021 21.4 0.1 0.00061 19.9 0.1 1.8 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 CAR26589.1 - 0.00021 20.5 0.0 0.0092 15.2 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein T2SE PF00437.15 CAR26589.1 - 0.00057 18.8 0.1 0.0011 17.9 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 CAR26589.1 - 0.0006 19.2 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 CAR26589.1 - 0.0022 17.4 0.1 0.0091 15.4 0.0 1.9 2 0 0 2 2 2 1 FtsK/SpoIIIE family Zot PF05707.7 CAR26589.1 - 0.0025 17.2 0.1 0.012 15.1 0.1 2.1 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_25 PF13481.1 CAR26589.1 - 0.0033 16.8 0.0 0.0077 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CAR26589.1 - 0.0065 16.1 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain KaiC PF06745.8 CAR26589.1 - 0.015 14.4 2.4 0.038 13.0 0.2 2.5 3 1 0 3 3 3 0 KaiC AAA_16 PF13191.1 CAR26589.1 - 0.015 15.2 0.0 0.072 13.0 0.0 2.2 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 CAR26589.1 - 0.037 13.6 0.1 0.11 12.1 0.0 1.9 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.1 CAR26589.1 - 0.068 13.4 0.0 0.068 13.4 0.0 4.4 2 1 1 3 3 1 0 AAA domain Glyco_hydro_32N PF00251.15 CAR26590.1 - 1.5e-83 280.7 5.2 2.5e-83 280.0 3.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 CAR26590.1 - 6.9e-06 26.3 0.1 2.4e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal MFS_1 PF07690.11 CAR26591.1 - 1.4e-27 96.3 20.2 1.4e-27 96.3 14.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4064 PF13273.1 CAR26591.1 - 8.4 6.5 11.9 1.2 9.3 0.6 3.7 4 1 1 5 5 5 0 Protein of unknown function (DUF4064) EF-hand_1 PF00036.27 CAR26592.1 - 4.6e-24 81.8 12.9 1.2e-05 24.2 0.3 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 CAR26592.1 - 3.1e-19 67.0 5.7 0.00014 21.4 0.2 4.5 4 1 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 CAR26592.1 - 2.2e-18 66.1 6.3 4.9e-10 39.4 0.9 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CAR26592.1 - 7.5e-15 53.5 15.8 0.0014 17.9 0.3 4.6 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 CAR26592.1 - 2.5e-13 49.4 14.0 0.0012 18.3 0.0 4.5 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.2 CAR26592.1 - 1.1e-06 28.3 9.6 0.016 14.9 0.3 4.0 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CAR26592.1 - 1.5e-05 24.9 0.0 0.023 14.7 0.0 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 CAR26592.1 - 0.00076 19.3 0.0 1.3 8.9 0.0 3.1 2 1 1 3 3 3 2 EF-hand domain Diphthamide_syn PF01866.12 CAR26593.1 - 5.2e-46 157.2 0.0 1.3e-22 80.4 0.0 2.1 2 0 0 2 2 2 2 Putative diphthamide synthesis protein UL73_N PF12522.3 CAR26593.1 - 0.39 10.2 4.1 1.1 8.8 2.9 1.7 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal Amidohydro_2 PF04909.9 CAR26594.1 - 4.2e-08 33.0 0.0 9.8e-08 31.8 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 CAR26594.1 - 1.3e-07 31.9 0.0 1.8e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Proteasom_Rpn13 PF04683.8 CAR26595.1 - 1.4e-22 79.5 0.0 1.9e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor CinA PF02464.12 CAR26596.1 - 8.1e-32 109.8 0.0 9.4e-32 109.6 0.0 1.0 1 0 0 1 1 1 1 Competence-damaged protein Ded_cyto PF06920.8 CAR26597.1 - 3.2e-20 72.1 0.0 8.5e-20 70.7 0.0 1.7 1 0 0 1 1 1 1 Dedicator of cytokinesis DUF3819 PF12842.2 CAR26597.1 - 0.018 14.7 0.1 0.044 13.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) PP-binding PF00550.20 CAR26598.1 - 3.7e-08 33.5 0.4 5e-08 33.1 0.3 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 CAR26598.1 - 2.7e-06 27.3 0.6 4e-06 26.7 0.4 1.2 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 CAR26598.1 - 0.0079 16.2 0.3 0.013 15.5 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1493) LRR_8 PF13855.1 CAR26599.1 - 5.3e-41 138.1 60.9 5.4e-12 45.2 2.4 6.1 3 1 5 8 8 8 6 Leucine rich repeat LRR_4 PF12799.2 CAR26599.1 - 5e-39 131.3 54.5 6.9e-11 41.5 3.0 6.8 3 1 5 8 8 8 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CAR26599.1 - 3.7e-12 44.4 37.2 0.041 13.8 0.3 10.7 10 1 0 10 10 10 4 Leucine Rich Repeat LRR_7 PF13504.1 CAR26599.1 - 2.2e-09 35.9 15.2 0.34 11.2 0.1 8.4 9 1 1 10 10 10 4 Leucine rich repeat LRR_6 PF13516.1 CAR26599.1 - 2.2e-08 33.3 27.8 0.38 10.9 0.1 10.2 8 4 3 11 11 11 4 Leucine Rich repeat LRR_9 PF14580.1 CAR26599.1 - 7.6e-08 32.1 15.1 1.7e-05 24.4 3.4 3.6 1 1 3 4 4 4 3 Leucine-rich repeat DUF3744 PF12558.3 CAR26599.1 - 0.18 12.2 12.1 1.1 9.7 0.3 4.3 2 2 2 4 4 4 0 ATP-binding cassette cobalt transporter tRNA-synt_2b PF00587.20 CAR26600.1 - 4.3e-49 166.3 0.0 7.5e-49 165.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CAR26600.1 - 2.9e-17 62.3 0.0 5.4e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain APG17 PF04108.7 CAR26601.1 - 1.6e-98 330.2 18.7 1.8e-98 330.0 12.9 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 Cluap1 PF10234.4 CAR26601.1 - 0.018 14.2 13.5 0.006 15.8 5.8 2.5 1 1 1 2 2 2 0 Clusterin-associated protein-1 IncA PF04156.9 CAR26601.1 - 0.12 11.9 19.3 3.6 7.1 5.9 3.6 1 1 2 3 3 3 0 IncA protein 4HB_MCP_1 PF12729.2 CAR26601.1 - 1.5 8.1 13.2 0.082 12.2 0.7 3.0 3 1 0 3 3 3 0 Four helix bundle sensory module for signal transduction Lip_prot_lig_C PF10437.4 CAR26601.1 - 1.5 8.5 6.5 2.7 7.7 0.1 3.9 4 2 1 5 5 5 0 Bacterial lipoate protein ligase C-terminus G-patch PF01585.18 CAR26602.1 - 3.5e-13 49.0 2.2 7e-13 48.1 1.5 1.5 1 0 0 1 1 1 1 G-patch domain GCFC PF07842.7 CAR26602.1 - 1e-06 28.3 2.5 2.1e-06 27.2 1.7 1.4 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch_2 PF12656.2 CAR26602.1 - 1.4e-06 28.0 0.3 3e-06 26.9 0.2 1.5 1 0 0 1 1 1 1 DExH-box splicing factor binding site FAM196 PF15265.1 CAR26602.1 - 0.058 12.6 0.1 0.082 12.1 0.1 1.1 1 0 0 1 1 1 0 FAM196 family CHCH PF06747.8 CAR26603.1 - 3.7e-08 33.0 4.7 7.1e-08 32.1 3.3 1.5 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 CAR26603.1 - 0.03 14.4 3.4 0.03 14.4 2.4 2.3 2 0 0 2 2 2 0 GCK domain GAGA_bind PF06217.7 CAR26603.1 - 0.84 9.5 20.1 1.3 8.9 3.7 2.4 2 0 0 2 2 2 0 GAGA binding protein-like family Synaptobrevin PF00957.16 CAR26604.1 - 2.5e-15 55.8 1.0 4.6e-15 54.9 0.7 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 CAR26604.1 - 8e-15 54.1 0.0 1.3e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Herpes_teg_N PF04843.7 CAR26604.1 - 0.091 12.1 0.1 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region FMN_dh PF01070.13 CAR26605.1 - 9.1e-119 396.4 0.0 1.1e-118 396.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 CAR26605.1 - 1.9e-20 72.4 0.0 5.1e-20 71.0 0.0 1.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 CAR26605.1 - 9.1e-06 24.8 0.0 3.7e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 CAR26605.1 - 4.9e-05 22.3 0.6 0.0018 17.2 0.0 2.4 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 CAR26605.1 - 0.00025 20.3 0.0 0.0004 19.6 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 CAR26605.1 - 0.029 13.6 0.6 3.5 6.8 0.0 2.3 1 1 0 2 2 2 0 Histidine biosynthesis protein ThiG PF05690.9 CAR26605.1 - 0.042 12.9 0.0 7.8 5.4 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG CNH PF00780.17 CAR26606.1 - 1.1e-18 67.6 0.9 3.3e-18 66.0 0.6 1.7 1 1 0 1 1 1 1 CNH domain PH PF00169.24 CAR26606.1 - 1.1e-08 35.1 3.3 4.6e-07 29.9 0.0 3.2 2 1 0 2 2 2 1 PH domain RhoGEF PF00621.15 CAR26606.1 - 4.8e-07 29.8 0.2 1.6e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 RhoGEF domain PH_5 PF15405.1 CAR26606.1 - 7.5e-05 22.6 2.0 0.00011 22.2 0.1 2.3 2 1 0 2 2 2 1 Pleckstrin homology domain adh_short PF00106.20 CAR26607.1 - 3.8e-20 72.4 0.0 5.8e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CAR26607.1 - 1.8e-08 34.2 0.3 7.1e-08 32.3 0.2 1.8 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 CAR26607.1 - 0.00084 18.1 0.0 0.0017 17.1 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CAR26607.1 - 0.084 12.2 0.1 0.21 10.9 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CAR26607.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding SPC25 PF06703.6 CAR26608.1 - 9.4e-38 129.3 0.9 1.1e-37 129.1 0.6 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) zf-RING_2 PF13639.1 CAR26609.1 - 8.6e-07 28.6 4.5 1.6e-06 27.8 3.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CAR26609.1 - 3.2e-06 26.7 1.5 7.3e-06 25.5 1.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAR26609.1 - 2e-05 24.4 6.1 4.2e-05 23.4 4.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAR26609.1 - 3.7e-05 23.3 4.7 7.8e-05 22.3 3.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CAR26609.1 - 5e-05 22.8 3.4 9.9e-05 21.9 2.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CAR26609.1 - 0.00021 21.0 6.6 0.0012 18.7 4.9 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CAR26609.1 - 0.00039 20.0 2.4 0.001 18.7 1.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 CAR26609.1 - 0.022 14.3 3.1 0.051 13.1 2.1 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FYVE PF01363.16 CAR26609.1 - 1.4 8.8 4.6 7.6 6.5 3.2 2.2 1 1 0 1 1 1 0 FYVE zinc finger DUF1900 PF08954.6 CAR26610.1 - 7.4e-47 158.2 0.0 1.6e-46 157.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 CAR26610.1 - 1.2e-28 98.5 0.1 2.2e-28 97.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 CAR26610.1 - 1e-21 75.9 0.5 8.2e-07 28.6 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 CAR26610.1 - 1.1e-06 27.0 0.3 0.0019 16.4 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 CAR26610.1 - 0.017 13.4 0.0 0.03 12.6 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain eIF2A PF08662.6 CAR26610.1 - 0.053 13.2 0.2 0.44 10.2 0.0 2.3 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A SEN1_N PF12726.2 CAR26611.1 - 1.2e-234 780.7 20.5 1.6e-234 780.2 14.2 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 CAR26611.1 - 5.1e-67 225.9 0.2 5.1e-67 225.9 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 CAR26611.1 - 6.8e-62 208.4 0.2 1.4e-61 207.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CAR26611.1 - 2.7e-11 43.0 0.0 1.6e-10 40.5 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 CAR26611.1 - 4.6e-07 29.6 0.0 0.00045 19.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 CAR26611.1 - 5.1e-06 26.1 0.1 0.058 12.9 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 CAR26611.1 - 0.026 13.9 0.2 0.34 10.3 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase IKKbetaNEMObind PF12179.3 CAR26612.1 - 0.017 14.9 0.2 0.063 13.1 0.1 2.0 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain IMPDH PF00478.20 CAR26613.1 - 1.4e-137 458.2 2.4 1.7e-137 458.0 1.7 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 CAR26613.1 - 1.1e-12 47.4 0.0 4.6e-06 26.3 0.0 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 CAR26613.1 - 2.4e-06 26.6 0.5 1.8e-05 23.7 0.7 2.0 2 1 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 CAR26613.1 - 2.9e-06 26.6 4.9 0.005 16.0 0.8 3.0 3 0 0 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.16 CAR26613.1 - 1.4e-05 24.5 1.7 0.004 16.4 0.1 2.5 1 1 1 2 2 2 2 Histidine biosynthesis protein Thioredoxin_2 PF13098.1 CAR26613.1 - 0.032 14.4 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain ThiG PF05690.9 CAR26613.1 - 0.063 12.3 1.3 0.2 10.6 0.3 2.2 3 0 0 3 3 3 0 Thiazole biosynthesis protein ThiG Metallophos PF00149.23 CAR26614.1 - 6.9e-43 146.3 0.4 1e-42 145.8 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2951 PF11166.3 CAR26614.1 - 0.037 13.8 0.1 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) WGG PF10273.4 CAR26615.1 - 8.3e-30 102.7 0.6 8.3e-30 102.7 0.4 1.6 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.2 CAR26615.1 - 0.19 11.7 1.9 0.29 11.1 0.7 1.8 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) DUF2457 PF10446.4 CAR26615.1 - 0.57 8.8 10.3 0.77 8.4 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Hid1 PF12722.2 CAR26616.1 - 1.6e-284 946.0 27.4 5.3e-284 944.3 19.0 1.7 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein RNR_inhib PF08591.5 CAR26617.1 - 9.5e-14 52.0 0.7 3.7e-13 50.2 0.5 1.8 1 1 0 1 1 1 1 Ribonucleotide reductase inhibitor Aminotran_3 PF00202.16 CAR26618.1 - 4.1e-109 364.5 0.0 4.9e-109 364.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 CAR26618.1 - 1.6e-05 24.1 0.0 3.5e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 CAR26618.1 - 0.011 14.7 0.0 0.075 11.9 0.0 2.0 2 0 0 2 2 2 0 Aminotransferase class I and II Pea-VEAacid PF08111.6 CAR26618.1 - 0.13 12.4 1.6 0.32 11.1 1.1 1.7 1 0 0 1 1 1 0 Pea-VEAacid family cNMP_binding PF00027.24 CAR26619.1 - 1.3e-41 140.3 0.3 2.2e-17 62.6 0.0 5.7 6 0 0 6 6 6 3 Cyclic nucleotide-binding domain Patatin PF01734.17 CAR26619.1 - 4.3e-20 72.5 0.6 1.6e-12 47.7 0.6 3.4 3 0 0 3 3 3 2 Patatin-like phospholipase LSM PF01423.17 CAR26620.1 - 3.1e-17 61.8 0.0 3.9e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain SH3_9 PF14604.1 CAR26620.1 - 0.014 14.9 0.1 0.89 9.1 0.0 2.2 2 0 0 2 2 2 0 Variant SH3 domain MRP-L47 PF06984.8 CAR26621.1 - 1.4e-26 92.2 1.4 4.4e-26 90.6 0.5 2.1 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF2884 PF11101.3 CAR26621.1 - 0.0016 17.8 0.8 0.0029 17.0 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2884) OGG_N PF07934.7 CAR26622.1 - 1.5e-20 73.2 0.6 2.5e-20 72.6 0.1 1.7 2 0 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 CAR26622.1 - 7.2e-19 68.0 0.0 1.2e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein PIF1 PF05970.9 CAR26623.1 - 6.4e-73 245.7 1.0 9.1e-70 235.4 0.7 2.4 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 CAR26623.1 - 8.9e-12 44.9 0.0 1.9e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CAR26623.1 - 0.00011 22.3 0.0 0.00027 21.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CAR26623.1 - 0.0013 17.9 0.1 0.0032 16.6 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI UvrD_C_2 PF13538.1 CAR26623.1 - 0.0035 17.4 0.2 0.017 15.2 0.0 2.4 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 CAR26623.1 - 0.021 14.5 0.3 0.047 13.4 0.2 1.5 1 0 0 1 1 1 0 Part of AAA domain PhoH PF02562.11 CAR26623.1 - 0.033 13.3 0.0 0.089 12.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein T2SE PF00437.15 CAR26623.1 - 0.036 12.9 0.0 0.061 12.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.9 CAR26623.1 - 0.057 13.1 0.3 0.49 10.1 0.2 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 CAR26623.1 - 0.94 9.7 4.6 2.9 8.2 0.1 3.2 2 1 1 3 3 3 0 ABC transporter Sec39 PF08314.6 CAR26624.1 - 2.4e-108 362.9 9.9 2.7e-108 362.8 6.9 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 DASH_Dad1 PF08649.5 CAR26624.1 - 0.009 15.6 0.7 0.073 12.7 0.1 2.8 3 0 0 3 3 3 1 DASH complex subunit Dad1 THOC7 PF05615.8 CAR26625.1 - 8.6e-15 55.2 6.8 8.6e-15 55.2 4.7 2.9 2 1 0 3 3 3 1 Tho complex subunit 7 YgaB PF14182.1 CAR26625.1 - 0.01 16.0 2.8 0.01 16.0 2.0 2.4 2 0 0 2 2 2 0 YgaB-like protein Laminin_II PF06009.7 CAR26625.1 - 0.017 14.8 2.2 0.017 14.8 1.5 2.3 2 1 0 2 2 2 0 Laminin Domain II Reo_sigmaC PF04582.7 CAR26625.1 - 0.021 14.0 1.6 0.034 13.3 1.1 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF3826 PF12875.2 CAR26625.1 - 0.023 14.3 5.1 0.81 9.3 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3826) DUF1640 PF07798.6 CAR26625.1 - 0.069 13.1 9.2 1.9 8.5 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1640) EMP24_GP25L PF01105.19 CAR26625.1 - 0.072 12.8 2.3 0.19 11.4 1.6 1.7 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF2730 PF10805.3 CAR26625.1 - 0.12 12.1 2.5 0.35 10.6 1.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) Fib_alpha PF08702.5 CAR26625.1 - 9.8 6.2 12.7 0.27 11.3 0.6 3.0 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Ribosomal_S3Ae PF01015.13 CAR26626.1 - 6.2e-77 257.3 7.4 7.3e-77 257.1 5.1 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Ras PF00071.17 CAR26627.1 - 1.8e-29 102.1 0.0 2.3e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR26627.1 - 2.3e-17 63.5 0.0 7.4e-17 61.9 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CAR26627.1 - 6.9e-05 22.1 0.0 8.5e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CAR26627.1 - 0.00012 21.2 0.1 0.00015 20.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CAR26627.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.24 CAR26628.1 - 5.6e-19 68.6 0.0 1.3e-18 67.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BAH PF01426.13 CAR26628.1 - 6.1e-17 61.4 0.1 1.6e-16 60.1 0.1 1.8 1 0 0 1 1 1 1 BAH domain AAA_16 PF13191.1 CAR26628.1 - 1.1e-08 35.3 2.9 1.2e-06 28.6 0.0 3.3 3 1 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 CAR26628.1 - 1.6e-06 28.2 0.0 7.1e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 CAR26628.1 - 7.8e-05 22.3 0.0 0.00016 21.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_17 PF13207.1 CAR26628.1 - 0.0032 18.2 1.6 0.026 15.3 0.0 3.1 2 0 0 2 2 2 1 AAA domain DUF1075 PF06388.6 CAR26628.1 - 0.0034 17.0 1.8 0.0034 17.0 1.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1075) ArgK PF03308.11 CAR26628.1 - 0.079 11.7 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 ArgK protein SUR7 PF06687.7 CAR26629.1 - 2e-10 40.6 5.2 2.7e-10 40.1 3.6 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF2207 PF09972.4 CAR26629.1 - 0.19 10.2 0.7 0.37 9.3 0.5 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) COPIIcoated_ERV PF07970.7 CAR26631.1 - 1.6e-28 99.8 0.0 2.5e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CAR26631.1 - 1.4e-17 63.4 0.0 2.6e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) IBR PF01485.16 CAR26633.1 - 5.5e-15 54.9 44.6 1e-07 31.6 2.6 3.8 3 1 1 4 4 4 3 IBR domain zf-RING_2 PF13639.1 CAR26633.1 - 6.1e-05 22.7 6.6 6.1e-05 22.7 4.6 4.8 3 2 2 5 5 5 1 Ring finger domain zf-C3HC4 PF00097.20 CAR26633.1 - 0.002 17.7 9.0 0.002 17.7 6.3 4.8 3 2 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAR26633.1 - 0.0068 16.3 8.1 0.0068 16.3 5.6 5.0 3 2 2 5 5 5 2 Zinc finger, C3HC4 type (RING finger) RWD PF05773.17 CAR26633.1 - 0.019 14.8 2.4 0.13 12.1 0.4 2.7 3 0 0 3 3 3 0 RWD domain DUF2387 PF09526.5 CAR26633.1 - 0.12 12.2 0.3 0.12 12.2 0.2 4.3 4 1 0 5 5 5 0 Probable metal-binding protein (DUF2387) SSrecog PF03531.9 CAR26634.1 - 4.5e-69 232.1 1.7 2.3e-41 141.5 0.1 2.5 2 0 0 2 2 2 2 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 CAR26634.1 - 5.7e-29 99.9 0.0 1e-26 92.7 0.0 2.6 2 0 0 2 2 2 2 Histone chaperone Rttp106-like Dak1 PF02733.12 CAR26635.1 - 1.4e-127 424.7 4.1 1.8e-127 424.4 2.8 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 CAR26635.1 - 3.8e-44 150.4 2.5 9e-44 149.2 1.7 1.7 1 0 0 1 1 1 1 DAK2 domain HTH_7 PF02796.10 CAR26635.1 - 0.16 11.8 0.1 0.51 10.2 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase BAR PF03114.13 CAR26636.1 - 1.9e-05 24.3 0.1 7.3e-05 22.3 0.0 1.8 1 1 0 1 1 1 1 BAR domain Zn_clus PF00172.13 CAR26637.1 - 1.5e-05 24.7 8.1 2.8e-05 23.9 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fib_alpha PF08702.5 CAR26637.1 - 7.8 6.6 11.9 0.046 13.8 0.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Hexokinase_1 PF00349.16 CAR26638.1 - 2.1e-10 40.3 0.0 6.2e-10 38.7 0.0 1.7 2 0 0 2 2 2 1 Hexokinase Hexokinase_2 PF03727.11 CAR26638.1 - 0.00066 18.9 0.0 0.2 10.8 0.0 2.3 1 1 0 2 2 2 2 Hexokinase Cyt-b5 PF00173.23 CAR26639.1 - 5.8e-10 38.8 0.0 9.7e-10 38.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain vATP-synt_AC39 PF01992.11 CAR26640.1 - 3.5e-82 276.2 0.7 4e-82 276.0 0.5 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Dor1 PF04124.7 CAR26641.1 - 8.8e-39 132.8 2.6 3.1e-37 127.8 1.8 2.2 1 1 0 1 1 1 1 Dor1-like family Sec5 PF15469.1 CAR26641.1 - 2.4e-06 27.3 0.5 1.1e-05 25.2 0.3 2.2 1 1 0 1 1 1 1 Exocyst complex component Sec5 MA3 PF02847.12 CAR26641.1 - 0.23 11.1 3.6 1.2 8.8 0.2 3.2 3 0 0 3 3 3 0 MA3 domain C2 PF00168.25 CAR26642.1 - 8.6e-42 140.8 1.1 2.4e-14 52.9 0.0 5.5 5 0 0 5 5 5 5 C2 domain Ribosomal_L6e PF01159.14 CAR26643.1 - 2e-37 127.7 0.7 2.7e-37 127.3 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e FKBP_C PF00254.23 CAR26644.1 - 1.2e-27 95.7 0.4 2.6e-26 91.4 0.0 2.7 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase RNase_H2-Ydr279 PF09468.5 CAR26644.1 - 0.54 9.4 29.0 0.36 9.9 8.9 2.4 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) GAGA_bind PF06217.7 CAR26644.1 - 1.9 8.3 26.7 3.8 7.3 2.6 2.4 2 0 0 2 2 2 0 GAGA binding protein-like family HMG-CoA_red PF00368.13 CAR26645.1 - 1.9e-156 520.4 1.0 2.5e-156 520.0 0.7 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 CAR26645.1 - 6e-40 136.4 0.1 1e-39 135.6 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 CAR26645.1 - 4e-11 42.5 7.7 1e-10 41.3 5.3 1.6 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Zn_clus PF00172.13 CAR26646.1 - 5.5e-05 22.9 8.4 0.0001 22.1 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sybindin PF04099.7 CAR26647.1 - 2.8e-17 62.7 0.3 3.5e-17 62.4 0.2 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 CAR26647.1 - 0.016 15.0 0.1 0.02 14.7 0.1 1.2 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region OstA_C PF04453.9 CAR26647.1 - 0.016 14.2 0.3 0.019 14.0 0.2 1.1 1 0 0 1 1 1 0 Organic solvent tolerance protein ABC2_membrane PF01061.19 CAR26648.1 - 2.3e-65 219.7 63.7 4.6e-41 140.3 10.5 2.9 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 CAR26648.1 - 2.3e-37 126.8 4.6 1.8e-32 111.0 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 CAR26648.1 - 2.1e-36 125.2 0.0 1.2e-18 67.7 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 CAR26648.1 - 6.2e-12 45.4 0.2 2.7e-11 43.3 0.1 2.1 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 CAR26648.1 - 5.9e-08 32.1 18.2 5.9e-08 32.1 12.6 3.9 2 2 0 2 2 2 1 ABC-2 family transporter protein AAA_25 PF13481.1 CAR26648.1 - 1.3e-05 24.7 0.0 0.0043 16.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 CAR26648.1 - 3.3e-05 23.9 0.1 0.0033 17.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 CAR26648.1 - 3.5e-05 23.0 0.0 0.00025 20.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 CAR26648.1 - 0.00022 20.7 0.2 0.00067 19.1 0.0 1.9 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 CAR26648.1 - 0.00074 19.0 0.6 0.023 14.1 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CAR26648.1 - 0.00077 19.6 0.2 0.0087 16.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 CAR26648.1 - 0.00078 19.9 0.0 0.7 10.3 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein AAA_21 PF13304.1 CAR26648.1 - 0.001 19.1 0.0 0.66 9.8 0.0 3.3 4 0 0 4 4 3 1 AAA domain FtsK_SpoIIIE PF01580.13 CAR26648.1 - 0.0018 17.8 0.1 0.52 9.7 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_18 PF13238.1 CAR26648.1 - 0.0027 18.0 0.5 0.026 14.8 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.1 CAR26648.1 - 0.003 18.3 0.5 0.034 14.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain SMC_N PF02463.14 CAR26648.1 - 0.0075 15.5 0.0 0.64 9.2 0.0 3.2 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 CAR26648.1 - 0.025 14.5 0.2 0.17 11.8 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 CAR26648.1 - 0.036 14.2 0.0 0.6 10.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.7 CAR26648.1 - 0.05 13.2 0.5 0.24 11.0 0.1 2.2 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 CAR26648.1 - 0.053 13.1 1.9 0.15 11.6 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 CAR26648.1 - 0.11 12.3 0.7 0.4 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 CAR26648.1 - 0.16 10.9 0.3 0.38 9.7 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.1 CAR26648.1 - 0.28 10.7 4.0 0.47 10.0 0.1 2.6 3 0 0 3 3 3 0 AAA domain ENTH PF01417.15 CAR26649.1 - 1.4e-43 147.7 0.1 2.2e-43 147.0 0.1 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 CAR26649.1 - 0.0055 15.4 0.0 0.008 14.9 0.0 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.14 CAR26649.1 - 0.016 14.7 1.3 0.13 11.9 0.0 2.2 2 0 0 2 2 2 0 VHS domain BUD22 PF09073.5 CAR26649.1 - 1.9 7.4 13.1 3.8 6.4 9.1 1.5 1 1 0 1 1 1 0 BUD22 Pro_isomerase PF00160.16 CAR26650.1 - 2.8e-46 157.5 0.1 3.4e-46 157.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TFR_dimer PF04253.10 CAR26651.1 - 4.2e-10 39.2 0.1 8.2e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 CAR26651.1 - 5.4e-06 26.2 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 CAR26651.1 - 0.084 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 PA domain Cupin_5 PF06172.6 CAR26652.1 - 3.3e-32 111.2 0.0 5.2e-32 110.6 0.0 1.3 1 1 0 1 1 1 1 Cupin superfamily (DUF985) Dus PF01207.12 CAR26653.1 - 1.8e-78 263.4 0.0 2.3e-78 263.1 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) PyocinActivator PF11112.3 CAR26653.1 - 0.043 13.6 0.3 10 6.0 0.0 2.7 3 0 0 3 3 3 0 Pyocin activator protein PrtN zf-H2C2_2 PF13465.1 CAR26654.1 - 8.5e-07 28.9 9.5 1.9e-05 24.7 3.5 2.6 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 CAR26654.1 - 0.00013 22.0 20.7 0.00031 20.9 2.0 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CAR26654.1 - 0.00063 19.8 14.1 0.0076 16.5 1.7 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger Methyltransf_16 PF10294.4 CAR26655.1 - 3.9e-21 75.2 0.0 6.6e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 CAR26655.1 - 5.7e-08 32.2 0.0 1e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.15 CAR26655.1 - 4.3e-07 29.2 0.0 8.1e-07 28.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.2 CAR26655.1 - 1.7e-06 28.5 0.0 2.9e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CAR26655.1 - 6.8e-06 25.5 0.0 1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 CAR26655.1 - 1.3e-05 24.9 0.0 1.9e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAR26655.1 - 5.7e-05 23.5 0.0 0.0001 22.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CAR26655.1 - 9.4e-05 22.4 0.0 0.00015 21.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 CAR26655.1 - 0.0009 18.4 0.0 0.0018 17.4 0.0 1.5 1 1 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_11 PF08241.7 CAR26655.1 - 0.0013 19.1 0.0 0.0033 17.8 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAR26655.1 - 0.0081 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF3113 PF11310.3 CAR26655.1 - 0.12 12.1 0.7 0.29 10.8 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3113) Allantoicase PF03561.10 CAR26656.1 - 3.7e-94 312.1 0.5 2.1e-55 186.3 0.0 2.8 2 1 0 2 2 2 2 Allantoicase repeat F5_F8_type_C PF00754.20 CAR26656.1 - 0.019 14.7 2.2 0.83 9.4 0.0 2.9 3 1 0 3 3 3 0 F5/8 type C domain ApoO PF09769.4 CAR26657.1 - 1.8e-41 141.4 0.0 2.9e-41 140.8 0.0 1.3 1 0 0 1 1 1 1 Apolipoprotein O FAD_binding_6 PF00970.19 CAR26658.1 - 2.2e-11 43.7 0.0 3.9e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.17 CAR26658.1 - 1.3e-09 38.3 0.0 3.4e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Globin NAD_binding_1 PF00175.16 CAR26658.1 - 1.2e-06 29.0 0.0 5.9e-06 26.8 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Protoglobin PF11563.3 CAR26658.1 - 0.0005 19.7 0.2 0.0012 18.5 0.2 1.6 1 1 0 1 1 1 1 Protoglobin Scm3 PF10384.4 CAR26658.1 - 0.00092 18.6 0.3 0.0054 16.1 0.4 2.0 2 0 0 2 2 2 1 Centromere protein Scm3 Hemerythrin PF01814.18 CAR26658.1 - 0.14 12.3 0.6 2 8.5 0.0 2.8 3 0 0 3 3 3 0 Hemerythrin HHE cation binding domain PTCB-BRCT PF12738.2 CAR26659.1 - 1.6e-20 72.6 0.2 5.2e-12 45.4 0.0 4.4 4 0 0 4 4 4 2 twin BRCT domain BRCT PF00533.21 CAR26659.1 - 2.7e-20 72.3 10.0 2.7e-06 27.4 0.0 5.4 5 0 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain zf-C4 PF00105.13 CAR26659.1 - 0.18 12.0 0.6 0.43 10.8 0.4 1.6 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) AA_permease_2 PF13520.1 CAR26660.1 - 6.8e-62 209.3 47.3 8.3e-62 209.0 32.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CAR26660.1 - 2.6e-19 68.9 38.9 4.2e-19 68.2 27.0 1.2 1 0 0 1 1 1 1 Amino acid permease DUF3259 PF11652.3 CAR26661.1 - 0.079 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3259) Ank_2 PF12796.2 CAR26662.1 - 2.1e-38 130.5 2.8 1.4e-15 57.4 0.0 4.0 1 1 2 4 4 4 3 Ankyrin repeats (3 copies) SPX PF03105.14 CAR26662.1 - 2.8e-28 99.4 14.8 1.1e-16 61.5 5.3 2.5 1 1 1 2 2 2 2 SPX domain Ank PF00023.25 CAR26662.1 - 9.1e-27 91.5 4.7 4.3e-06 26.2 0.0 6.8 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 CAR26662.1 - 1e-25 89.1 1.4 1.7e-06 28.1 0.0 6.5 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 CAR26662.1 - 1.3e-22 79.6 0.9 9.6e-08 32.3 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CAR26662.1 - 2.7e-22 76.6 0.3 0.00052 20.0 0.0 6.8 6 0 0 6 6 6 5 Ankyrin repeat GDPD PF03009.12 CAR26662.1 - 0.011 15.3 0.0 0.1 12.0 0.0 2.5 2 1 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 CAR26663.1 - 8.8e-42 141.3 0.4 4.8e-20 71.6 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CAR26663.1 - 7.8e-37 123.2 3.1 7.2e-09 35.0 0.0 6.1 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 CAR26663.1 - 1.5e-34 117.7 1.6 1.2e-07 32.0 0.0 5.3 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 CAR26663.1 - 3.1e-31 106.6 3.6 5.3e-09 36.0 0.0 6.0 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 CAR26663.1 - 2e-29 98.6 0.5 2.2e-05 24.2 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Shal-type PF11601.3 CAR26663.1 - 0.0092 15.4 0.0 1.7 8.2 0.0 2.9 3 0 0 3 3 3 1 Shal-type voltage-gated potassium channels Band_7 PF01145.20 CAR26664.1 - 7.6e-21 74.8 0.4 1.1e-20 74.2 0.2 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family E_Pc_C PF06752.7 CAR26664.1 - 0.14 11.6 0.0 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 Enhancer of Polycomb C-terminus Spo12 PF05032.7 CAR26665.1 - 3.9e-20 71.1 5.1 3.9e-20 71.1 3.6 1.8 2 0 0 2 2 2 1 Spo12 family SMI1_KNR4 PF09346.5 CAR26666.1 - 5.3e-34 117.0 0.1 3.4e-32 111.2 0.0 3.0 2 1 1 3 3 3 1 SMI1 / KNR4 family (SUKH-1) DIE2_ALG10 PF04922.7 CAR26667.1 - 1.2e-123 412.9 33.1 1.2e-123 412.9 22.9 1.9 3 0 0 3 3 3 1 DIE2/ALG10 family DUF3361 PF11841.3 CAR26668.1 - 0.13 11.9 0.1 0.72 9.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) Pex24p PF06398.6 CAR26669.1 - 1.3e-69 234.7 0.6 2.4e-69 233.8 0.4 1.4 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF639 PF04842.7 CAR26669.1 - 0.014 13.5 0.2 0.02 13.0 0.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) NAAA-beta PF15508.1 CAR26669.1 - 0.021 15.1 0.2 0.19 12.0 0.0 2.5 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase PRT_C PF08372.5 CAR26669.1 - 0.056 12.9 1.7 0.058 12.9 0.2 1.7 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal PLA2_B PF01735.13 CAR26669.1 - 0.081 11.0 0.1 0.12 10.5 0.1 1.2 1 0 0 1 1 1 0 Lysophospholipase catalytic domain Reticulon PF02453.12 CAR26669.1 - 0.19 11.3 1.8 2.1 7.9 0.5 2.4 2 0 0 2 2 2 0 Reticulon WD40 PF00400.27 CAR26670.1 - 3.7e-14 51.9 11.0 1.7e-06 27.6 0.0 5.7 8 0 0 8 8 8 3 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CAR26670.1 - 0.0025 17.2 0.0 0.039 13.4 0.0 2.8 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF3312 PF11768.3 CAR26670.1 - 0.072 11.3 0.0 1.2 7.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Herpes_UL7 PF01677.11 CAR26670.1 - 0.09 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL7 like WD40 PF00400.27 CAR26671.1 - 1.1e-06 28.2 0.1 0.13 12.1 0.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat ILVD_EDD PF00920.16 CAR26673.1 - 1.1e-202 674.1 0.2 1.2e-202 673.9 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family SKG6 PF08693.5 CAR26674.1 - 1.3e-08 33.9 2.2 2.2e-08 33.2 1.5 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 CAR26674.1 - 0.0005 19.6 0.0 0.0015 18.0 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.1 CAR26674.1 - 0.0068 16.1 0.0 0.037 13.7 0.0 2.3 2 0 0 2 2 2 1 TMEM154 protein family Rax2 PF12768.2 CAR26674.1 - 0.024 13.8 0.1 0.069 12.3 0.0 1.8 2 0 0 2 2 2 0 Cortical protein marker for cell polarity FixQ PF05545.6 CAR26674.1 - 0.04 13.5 0.1 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ EphA2_TM PF14575.1 CAR26674.1 - 0.049 14.0 0.4 0.61 10.5 0.0 2.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF3377 PF11857.3 CAR26674.1 - 0.085 12.4 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) AAA_23 PF13476.1 CAR26674.1 - 0.27 11.5 6.1 0.55 10.5 4.2 1.6 1 0 0 1 1 1 0 AAA domain Shisa PF13908.1 CAR26674.1 - 0.78 9.8 0.0 0.78 9.8 0.0 4.0 4 2 0 4 4 4 0 Wnt and FGF inhibitory regulator Ribosomal_S4 PF00163.14 CAR26675.1 - 1.4e-25 89.4 1.3 2.3e-25 88.7 0.9 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CAR26675.1 - 3.3e-10 39.2 0.0 8.1e-10 37.9 0.0 1.7 2 0 0 2 2 2 1 S4 domain Herpes_LAMP2 PF06126.6 CAR26675.1 - 0.027 12.8 0.1 0.033 12.6 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 Ribosomal_L6 PF00347.18 CAR26676.1 - 1.5e-27 95.8 1.0 1.9e-14 53.9 0.1 2.3 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_L3 PF00297.17 CAR26677.1 - 5.5e-43 147.2 2.4 7.8e-42 143.4 1.7 2.0 1 1 0 1 1 1 1 Ribosomal protein L3 CRM1_C PF08767.6 CAR26678.1 - 1.4e-128 428.3 3.9 1.4e-128 428.3 2.7 2.6 2 1 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.7 CAR26678.1 - 3.2e-37 127.7 4.2 3.2e-37 127.7 2.9 4.2 5 0 0 5 5 5 1 Exportin 1-like protein IBN_N PF03810.14 CAR26678.1 - 2.6e-14 52.8 0.2 3.1e-13 49.4 0.1 3.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain DEAD PF00270.24 CAR26680.1 - 1.1e-37 129.1 0.8 3e-36 124.4 0.2 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR26680.1 - 1.6e-26 91.9 0.1 3.3e-26 90.9 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 CAR26680.1 - 0.00039 20.4 0.0 0.0032 17.4 0.0 2.2 2 0 0 2 2 2 1 Helicase C-terminal domain GCOM2 PF15328.1 CAR26680.1 - 0.023 14.4 9.3 0.14 11.9 5.7 2.2 2 0 0 2 2 2 0 Putative GRINL1B complex locus protein 2 AAA_30 PF13604.1 CAR26680.1 - 0.03 13.9 0.0 0.062 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain CMS1 PF14617.1 CAR26680.1 - 0.13 11.3 0.1 0.13 11.3 0.0 3.2 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit Tim54 PF11711.3 CAR26680.1 - 0.37 9.3 6.3 0.59 8.6 4.4 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 XRN_N PF03159.13 CAR26681.1 - 3.5e-108 360.4 3.7 3.9e-107 357.0 0.0 2.6 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus RTA1 PF04479.8 CAR26683.1 - 2.7e-70 236.3 9.4 3.8e-70 235.9 6.5 1.2 1 0 0 1 1 1 1 RTA1 like protein Acyltransferase PF01553.16 CAR26684.1 - 3.1e-06 26.6 0.0 2.5e-05 23.7 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase SecY PF00344.15 CAR26684.1 - 0.022 13.7 0.3 1.4 7.7 0.0 2.5 2 1 0 2 2 2 0 SecY translocase TRAPP PF04051.11 CAR26685.1 - 1.9e-36 124.9 0.0 2.7e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF111 PF01969.12 CAR26685.1 - 0.046 12.5 0.0 0.21 10.3 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function DUF111 Dsl1_N PF11988.3 CAR26685.1 - 0.048 12.5 0.1 0.089 11.6 0.0 1.5 2 0 0 2 2 2 0 Retrograde transport protein Dsl1 N terminal Nro1 PF12753.2 CAR26686.1 - 1.4e-157 524.8 25.8 1.6e-157 524.6 17.9 1.0 1 0 0 1 1 1 1 Nuclear pore complex subunit Nro1 MerR_2 PF13591.1 CAR26686.1 - 0.011 15.2 0.4 0.044 13.3 0.0 2.2 2 0 0 2 2 2 0 MerR HTH family regulatory protein Abi_2 PF07751.6 CAR26686.1 - 0.043 13.9 1.8 0.095 12.8 1.2 1.5 1 0 0 1 1 1 0 Abi-like protein TPR_12 PF13424.1 CAR26686.1 - 0.049 13.5 2.7 0.12 12.2 1.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TP_methylase PF00590.15 CAR26687.1 - 8.6e-40 136.6 0.2 1.4e-39 135.9 0.1 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 CAR26687.1 - 3.5e-10 40.0 0.0 8.3e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.1 CAR26687.1 - 0.00073 18.4 0.6 0.0017 17.2 0.4 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.1 CAR26687.1 - 0.13 11.6 0.2 13 5.1 0.0 2.6 2 0 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal Hydrolase_like PF13242.1 CAR26688.1 - 3e-24 84.5 0.0 6.1e-24 83.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 CAR26688.1 - 4.4e-24 84.3 0.0 7.8e-24 83.4 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CAR26688.1 - 0.00011 22.4 0.1 0.25 11.5 0.0 3.2 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CAR26688.1 - 0.00015 22.2 0.0 0.0026 18.1 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Endothelin PF00322.12 CAR26688.1 - 0.061 12.5 0.1 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Endothelin family zf-AN1 PF01428.11 CAR26689.1 - 2.2e-09 37.0 12.9 3.7e-09 36.3 8.9 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger MutL PF13941.1 CAR26689.1 - 0.0068 14.7 0.0 0.0077 14.6 0.0 1.1 1 0 0 1 1 1 1 MutL protein CbiG_C PF01890.11 CAR26689.1 - 0.11 12.7 0.1 0.16 12.2 0.1 1.3 1 0 0 1 1 1 0 Cobalamin synthesis G C-terminus APC_CDC26 PF10471.4 CAR26689.1 - 0.26 12.0 3.2 0.52 11.0 2.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 CIAPIN1 PF05093.8 CAR26690.1 - 6e-35 119.3 5.6 6e-35 119.3 3.9 2.1 2 0 0 2 2 2 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Dicty_REP PF05086.7 CAR26690.1 - 0.014 13.1 5.2 0.018 12.8 3.6 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Flavoprotein PF02441.14 CAR26691.1 - 4.2e-40 136.4 8.0 4.9e-39 132.9 5.5 2.3 1 1 0 1 1 1 1 Flavoprotein NOB1_Zn_bind PF08772.6 CAR26692.1 - 3.5e-26 90.8 0.1 8e-26 89.6 0.1 1.6 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf-RING_3 PF14369.1 CAR26692.1 - 0.079 12.9 0.5 0.16 11.9 0.3 1.5 1 0 0 1 1 1 0 zinc-finger SAGA-Tad1 PF12767.2 CAR26692.1 - 0.66 9.6 14.7 1.3 8.6 10.2 1.5 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF4367 PF14285.1 CAR26692.1 - 1.1 8.5 3.3 14 4.9 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4367) Ebola_NP PF05505.7 CAR26692.1 - 9.9 4.0 18.3 14 3.5 12.7 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein SGS PF05002.10 CAR26693.1 - 2.4e-28 97.6 1.6 2.4e-28 97.6 1.1 2.5 3 0 0 3 3 3 1 SGS domain CS PF04969.11 CAR26693.1 - 2.9e-15 56.5 0.6 5.9e-15 55.5 0.4 1.5 1 0 0 1 1 1 1 CS domain MAP65_ASE1 PF03999.7 CAR26694.1 - 3.4e-75 253.8 28.2 3.4e-75 253.8 19.5 2.2 1 1 1 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) Retrotrans_gag PF03732.12 CAR26694.1 - 0.015 15.3 1.2 2.7 8.1 0.5 3.4 2 0 0 2 2 2 0 Retrotransposon gag protein DUF1870 PF08965.5 CAR26694.1 - 0.027 14.1 0.1 0.11 12.1 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1870) DUF2340 PF10209.4 CAR26695.1 - 4.9e-57 191.3 2.1 5.7e-57 191.1 1.4 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) DUF676 PF05057.9 CAR26696.1 - 2.6e-49 167.4 0.0 4e-49 166.8 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 CAR26696.1 - 2.5e-05 23.9 0.0 6.3e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_5 PF12695.2 CAR26696.1 - 0.0011 18.7 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CAR26696.1 - 0.0097 15.8 0.0 0.11 12.3 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 CAR26696.1 - 0.14 11.8 0.0 1.7 8.2 0.0 2.3 2 1 0 2 2 2 0 Lipase (class 3) Macoilin PF09726.4 CAR26697.1 - 0.037 12.3 2.7 0.044 12.0 1.8 1.1 1 0 0 1 1 1 0 Transmembrane protein Pkinase PF00069.20 CAR26698.1 - 2e-52 177.9 0.0 2.5e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR26698.1 - 2.7e-16 59.4 0.0 4.1e-16 58.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CAR26698.1 - 6.8e-07 29.2 0.0 2.9e-06 27.2 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CAR26698.1 - 0.011 15.2 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Myc_N PF01056.13 CAR26699.1 - 0.063 12.4 2.1 0.076 12.1 1.4 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Daxx PF03344.10 CAR26699.1 - 0.11 10.9 5.2 0.14 10.6 3.6 1.1 1 0 0 1 1 1 0 Daxx Family Ribosomal_L3 PF00297.17 CAR26700.1 - 8.5e-117 389.2 7.4 1e-116 388.9 5.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 PHD PF00628.24 CAR26701.1 - 3.4e-07 29.8 8.2 6e-07 29.0 5.7 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 CAR26701.1 - 0.0022 18.1 0.8 0.005 16.9 0.5 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain Ecl1 PF12855.2 CAR26701.1 - 0.02 14.1 0.8 0.059 12.6 0.6 1.9 1 0 0 1 1 1 0 Life-span regulatory factor zf-HC5HC2H_2 PF13832.1 CAR26701.1 - 0.032 14.2 0.4 0.072 13.0 0.3 1.6 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING-like PF08746.6 CAR26701.1 - 0.17 11.8 4.1 0.37 10.8 2.8 1.6 1 1 0 1 1 1 0 RING-like domain Metallothio_Pro PF02069.11 CAR26701.1 - 5 7.0 8.7 1.2 8.9 2.6 2.4 1 1 0 2 2 2 0 Prokaryotic metallothionein Cytochrom_C1 PF02167.10 CAR26702.1 - 2.3e-82 275.8 0.0 2.9e-82 275.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 CAR26702.1 - 0.00083 19.4 0.0 0.0017 18.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 CAR26702.1 - 0.0064 17.2 0.2 0.019 15.7 0.1 1.9 1 1 0 1 1 1 1 Cytochrome c zf-H2C2_2 PF13465.1 CAR26703.1 - 4.7e-20 70.8 25.4 1.1e-09 38.0 0.7 4.7 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.21 CAR26703.1 - 1.5e-16 59.6 37.1 9.8e-06 25.6 0.1 5.3 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CAR26703.1 - 2.4e-13 49.3 24.8 0.00075 19.6 0.1 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 CAR26703.1 - 2.8e-05 24.1 14.7 0.028 14.6 0.1 4.9 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CAR26703.1 - 0.0035 17.4 14.6 0.095 12.8 0.0 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CAR26703.1 - 6.7 6.7 18.8 2.5 8.1 0.0 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger KRAB PF01352.22 CAR26704.1 - 0.063 12.7 0.2 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 KRAB box VOMI PF03762.12 CAR26704.1 - 0.08 12.8 0.2 0.17 11.8 0.0 1.5 2 0 0 2 2 2 0 Vitelline membrane outer layer protein I (VOMI) TRAPP PF04051.11 CAR26705.1 - 1.1e-30 106.1 0.1 2.9e-30 104.8 0.0 1.7 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component FCH PF00611.18 CAR26706.1 - 1.9e-23 82.4 1.0 1.6e-22 79.4 0.1 2.9 1 1 1 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 CAR26706.1 - 1.3e-21 75.8 0.5 2.2e-10 39.9 0.1 3.0 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.23 CAR26706.1 - 1.5e-21 75.4 0.2 2.2e-10 39.7 0.1 2.6 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 CAR26706.1 - 1.3e-11 43.8 0.0 5.1e-07 29.0 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain EST1 PF10374.4 CAR26706.1 - 0.0079 16.1 5.2 0.17 11.8 1.4 2.5 2 0 0 2 2 2 1 Telomerase activating protein Est1 SH3_3 PF08239.6 CAR26706.1 - 0.0096 16.0 1.0 5.4 7.2 0.1 2.6 2 0 0 2 2 2 2 Bacterial SH3 domain DUF4200 PF13863.1 CAR26706.1 - 0.42 10.5 22.7 0.05 13.5 5.9 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4200) DUF4407 PF14362.1 CAR26706.1 - 4 6.3 7.2 2.9 6.7 2.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF2417 PF10329.4 CAR26707.1 - 2e-71 240.0 4.0 2.7e-71 239.6 2.7 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 CAR26707.1 - 4.7e-11 42.9 0.0 7e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAR26707.1 - 1.9e-07 30.8 0.0 4.6e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold FHA PF00498.21 CAR26708.1 - 3.8e-14 52.5 0.0 9e-14 51.3 0.0 1.7 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 CAR26708.1 - 5.4e-07 29.3 10.1 9.1e-07 28.6 7.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CAR26708.1 - 4.8e-06 26.6 5.2 9.5e-06 25.6 3.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CAR26708.1 - 0.00047 19.7 10.6 0.00082 18.9 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CAR26708.1 - 0.0057 16.4 4.2 0.01 15.6 2.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 CAR26708.1 - 0.038 13.7 12.0 0.061 13.0 8.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CAR26708.1 - 0.054 13.5 11.8 0.099 12.6 8.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 CAR26708.1 - 0.17 11.9 5.7 0.38 10.7 4.0 1.6 1 0 0 1 1 1 0 RING-like domain Sec_GG PF07549.9 CAR26708.1 - 0.59 9.4 3.9 0.17 11.1 0.4 1.9 2 0 0 2 2 2 0 SecD/SecF GG Motif zf-HC5HC2H PF13771.1 CAR26708.1 - 2.1 8.5 8.5 3.8 7.7 5.9 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain Malate_synthase PF01274.17 CAR26709.1 - 9.8e-215 713.4 0.0 1.2e-214 713.2 0.0 1.0 1 0 0 1 1 1 1 Malate synthase NMT1 PF09084.6 CAR26710.1 - 5.3e-10 39.2 0.0 8.6e-10 38.5 0.0 1.5 1 1 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.2 CAR26710.1 - 2.1e-08 33.8 0.0 2.7e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_2 PF13379.1 CAR26710.1 - 4.6e-08 32.7 0.0 6.6e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family SBP_bac_3 PF00497.15 CAR26710.1 - 8.7e-06 25.1 0.0 1.9e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 LysR_substrate PF03466.15 CAR26710.1 - 0.019 14.0 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 LysR substrate binding domain DCP2 PF05026.8 CAR26711.1 - 8.2e-32 108.9 1.2 2.2e-31 107.5 0.8 1.8 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 CAR26711.1 - 1.3e-13 50.7 0.0 2.6e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain DUF2392 PF10288.4 CAR26712.1 - 2.4e-30 105.0 0.1 5.1e-30 103.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) zf-FPG_IleRS PF06827.9 CAR26712.1 - 0.14 11.8 2.3 0.52 10.0 1.6 2.1 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS Pcc1 PF09341.5 CAR26713.1 - 5.8e-21 74.3 0.0 6.5e-21 74.1 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 DUF1336 PF07059.7 CAR26713.1 - 0.038 13.4 0.0 0.043 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1336) DHHA2 PF02833.9 CAR26713.1 - 0.062 13.4 0.1 0.074 13.2 0.1 1.1 1 0 0 1 1 1 0 DHHA2 domain PIN_4 PF13638.1 CAR26714.1 - 1.4e-11 44.5 0.2 1.4e-11 44.5 0.2 2.3 2 1 0 2 2 2 1 PIN domain PEPCK_ATP PF01293.15 CAR26716.1 - 1.9e-219 728.9 0.0 2.3e-219 728.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 CAR26716.1 - 0.007 16.2 0.0 0.062 13.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CAR26716.1 - 0.019 14.3 0.0 0.051 12.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 CAR26716.1 - 0.052 12.6 0.0 0.094 11.8 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.1 CAR26716.1 - 0.067 12.7 0.1 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MRFAP1 PF15155.1 CAR26716.1 - 0.073 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 MORF4 family-associated protein1 PTPA PF03095.10 CAR26717.1 - 3.5e-109 364.5 0.0 8.2e-109 363.3 0.0 1.5 2 0 0 2 2 2 1 Phosphotyrosyl phosphate activator (PTPA) protein Usp PF00582.21 CAR26718.1 - 0.0026 17.9 0.4 0.038 14.1 0.0 2.2 2 0 0 2 2 2 1 Universal stress protein family Nop14 PF04147.7 CAR26718.1 - 0.0056 14.6 4.1 0.0086 14.0 2.8 1.3 1 0 0 1 1 1 1 Nop14-like family Daxx PF03344.10 CAR26718.1 - 0.091 11.2 6.2 0.12 10.8 4.3 1.1 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 CAR26718.1 - 0.11 11.1 8.0 0.17 10.5 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RXT2_N PF08595.6 CAR26718.1 - 0.83 9.4 5.4 1.2 8.9 3.0 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal NOA36 PF06524.7 CAR26718.1 - 3.5 6.7 5.6 5.7 6.1 3.9 1.3 1 0 0 1 1 1 0 NOA36 protein DAO PF01266.19 CAR26719.1 - 1.2e-50 172.4 0.0 1.6e-50 172.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CAR26719.1 - 2.9e-13 49.4 0.8 8.7e-13 47.8 0.5 1.7 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 CAR26719.1 - 3.5e-11 42.8 0.1 3.5e-06 26.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CAR26719.1 - 1.2e-05 25.2 0.4 0.0011 18.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CAR26719.1 - 9.6e-05 21.5 0.1 0.13 11.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 CAR26719.1 - 0.00026 20.1 0.1 0.055 12.5 0.0 2.2 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 CAR26719.1 - 0.00094 18.1 0.9 0.05 12.4 0.3 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 CAR26719.1 - 0.005 16.8 1.3 0.015 15.3 0.7 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 CAR26719.1 - 0.0056 15.1 0.7 0.011 14.2 0.5 1.4 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 CAR26719.1 - 0.078 11.8 0.3 0.18 10.7 0.2 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein RICTOR_M PF14666.1 CAR26719.1 - 0.12 11.3 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain 3HCDH_N PF02737.13 CAR26719.1 - 0.13 11.8 1.1 0.57 9.8 0.8 2.1 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UCH PF00443.24 CAR26720.1 - 6.2e-58 196.0 8.1 6.2e-58 196.0 5.6 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CAR26720.1 - 9.9e-25 87.5 15.9 1.7e-22 80.2 9.8 2.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase FYDLN_acid PF09538.5 CAR26720.1 - 8.2 7.0 10.3 2.3 8.8 1.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Myb_DNA-bind_6 PF13921.1 CAR26721.1 - 2e-31 107.8 4.3 1e-11 44.7 0.2 3.8 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CAR26721.1 - 2.8e-27 94.5 10.8 9.3e-12 44.8 0.1 4.2 3 1 0 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.3 CAR26721.1 - 0.014 15.2 2.3 6.2 6.7 1.6 3.2 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF2690 PF10901.3 CAR26721.1 - 0.081 12.9 0.1 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2690) Myb_DNA-bind_5 PF13873.1 CAR26721.1 - 0.46 10.4 6.1 1.4 8.8 0.2 3.7 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain DUF1748 PF08520.5 CAR26722.1 - 1.1e-29 101.8 0.0 1.2e-29 101.7 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Coa1 PF08695.5 CAR26723.1 - 7.6e-40 135.0 0.0 9.3e-40 134.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 SKG6 PF08693.5 CAR26724.1 - 0.011 14.9 0.4 0.026 13.8 0.3 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Peptidase_M42 PF05343.9 CAR26724.1 - 0.042 12.6 0.1 0.07 11.8 0.0 1.2 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase FH2 PF02181.18 CAR26725.1 - 9.7e-70 235.2 15.9 9.7e-70 235.2 11.0 2.8 3 1 0 3 3 3 1 Formin Homology 2 Domain Thiolase_N PF00108.18 CAR26726.1 - 3.9e-82 275.1 0.0 5.3e-82 274.7 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CAR26726.1 - 1.2e-48 163.5 0.4 2.1e-48 162.8 0.3 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CAR26726.1 - 0.00021 20.8 0.1 0.00071 19.1 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 CAR26726.1 - 0.52 10.0 2.6 0.67 9.6 0.0 2.4 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III RWD PF05773.17 CAR26727.1 - 0.038 13.8 0.1 0.038 13.8 0.1 1.4 1 1 0 1 1 1 0 RWD domain Pneumo_att_G PF05539.6 CAR26727.1 - 0.27 10.5 10.8 0.34 10.2 7.5 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Epimerase PF01370.16 CAR26728.1 - 1.7e-19 70.2 0.0 2.7e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CAR26728.1 - 3.3e-10 40.2 0.2 9.5e-10 38.7 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 CAR26728.1 - 3.3e-10 39.1 0.0 4.8e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CAR26728.1 - 3.4e-07 29.4 0.1 1e-05 24.6 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 CAR26728.1 - 1.7e-06 27.4 0.1 3.3e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 CAR26728.1 - 2.1e-05 24.5 0.0 5e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 CAR26728.1 - 8.4e-05 21.5 0.0 0.0056 15.6 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 CAR26728.1 - 0.00018 20.4 0.0 0.045 12.6 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain Saccharop_dh PF03435.13 CAR26728.1 - 0.002 17.1 0.0 0.0062 15.5 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase KR PF08659.5 CAR26728.1 - 0.037 13.6 0.0 0.074 12.7 0.0 1.5 1 0 0 1 1 1 0 KR domain DapB_N PF01113.15 CAR26728.1 - 0.087 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF1272 PF06906.6 CAR26728.1 - 0.11 12.4 0.0 0.31 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Catalase PF00199.14 CAR26729.1 - 8.5e-169 561.2 0.0 1.1e-168 560.8 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 CAR26729.1 - 1.1e-10 41.1 0.0 2.8e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive DUF4124 PF13511.1 CAR26729.1 - 0.043 13.8 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4124) MFS_1 PF07690.11 CAR26730.1 - 6e-32 110.7 29.2 6e-32 110.7 20.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 CAR26730.1 - 0.00014 20.1 3.0 0.00021 19.6 2.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 CAR26730.1 - 0.00041 18.5 0.6 0.00071 17.8 0.4 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector Romo1 PF10247.4 CAR26730.1 - 0.014 15.5 1.9 6.8 6.9 0.1 2.9 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 OATP PF03137.15 CAR26730.1 - 8.6 4.2 18.7 0.091 10.8 4.0 3.5 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Cornifin PF02389.10 CAR26731.1 - 4.9e-07 29.7 13.7 4.9e-07 29.7 9.5 2.9 1 1 0 2 2 2 1 Cornifin (SPRR) family DUF1205 PF06722.7 CAR26731.1 - 0.23 11.7 4.1 1.1e+02 3.0 2.9 4.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1205) MFS_1 PF07690.11 CAR26732.1 - 2.3e-07 29.8 3.8 6e-07 28.5 2.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily SBF PF01758.11 CAR26733.1 - 2.7e-52 176.9 12.9 2.7e-52 176.9 8.9 2.1 2 1 0 2 2 2 1 Sodium Bile acid symporter family BNR PF02012.15 CAR26734.1 - 1.5e-06 27.1 0.3 0.1 12.4 0.0 3.3 2 0 0 2 2 2 2 BNR/Asp-box repeat Nitr_red_alph_N PF14710.1 CAR26734.1 - 0.06 13.5 0.2 0.2 11.9 0.0 1.9 2 0 0 2 2 2 0 Respiratory nitrate reductase alpha N-terminal Mo-co_dimer PF03404.11 CAR26734.1 - 0.15 11.6 0.0 2.4 7.7 0.0 2.1 2 0 0 2 2 2 0 Mo-co oxidoreductase dimerisation domain DUP PF00674.13 CAR26735.1 - 1e-06 28.6 0.4 1e-06 28.6 0.3 2.4 3 0 0 3 3 3 1 DUP family Aminotran_3 PF00202.16 CAR26736.1 - 2.2e-82 276.6 0.0 6.2e-82 275.1 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 CAR26736.1 - 0.00011 21.4 0.0 0.00026 20.2 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase AAA_26 PF13500.1 CAR26737.1 - 6.3e-42 143.4 0.0 7.6e-42 143.1 0.0 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 CAR26737.1 - 0.11 11.9 0.1 2.3 7.6 0.0 2.3 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUP PF00674.13 CAR26738.1 - 2.3e-07 30.7 1.5 2.3e-07 30.7 1.0 2.2 2 0 0 2 2 2 1 DUP family DUF4532 PF15046.1 CAR26738.1 - 0.16 10.9 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4532) PepSY_TM_3 PF13706.1 CAR26739.1 - 0.27 10.6 1.5 0.5 9.8 1.1 1.4 1 0 0 1 1 1 0 PepSY-associated TM helix DUP PF00674.13 CAR26740.1 - 3.5e-27 94.4 6.6 1.7e-15 56.8 0.0 2.4 2 0 0 2 2 2 2 DUP family PNTB PF02233.11 CAR26740.1 - 0.052 12.3 0.0 0.13 11.0 0.1 1.5 2 0 0 2 2 2 0 NAD(P) transhydrogenase beta subunit DUF1445 PF07286.7 CAR26742.1 - 4e-52 175.6 0.0 5.1e-52 175.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) Transp_cyt_pur PF02133.10 CAR26743.1 - 1.1e-81 274.6 23.3 1.3e-81 274.3 16.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Bac_luciferase PF00296.15 CAR26744.1 - 4.5e-53 180.3 0.0 7.2e-53 179.6 0.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase Sugar_tr PF00083.19 CAR26745.1 - 2.3e-78 263.8 28.9 2.8e-78 263.5 20.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR26745.1 - 2.3e-29 102.2 31.0 2.3e-29 102.2 21.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily ELFV_dehydrog PF00208.16 CAR26746.1 - 2.8e-80 269.4 3.7 3.4e-80 269.1 2.6 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 CAR26746.1 - 1.2e-45 154.3 0.0 2.6e-45 153.1 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 CAR26746.1 - 0.044 14.0 0.1 0.096 12.9 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Alb1 PF09135.6 CAR26747.1 - 1.5e-27 96.3 14.0 1.5e-27 96.3 9.7 1.8 2 0 0 2 2 2 1 Alb1 DUF4424 PF14415.1 CAR26747.1 - 0.036 13.5 2.7 0.032 13.7 0.7 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4424) Calreticulin PF00262.13 CAR26748.1 - 2.9e-124 414.4 1.1 3.6e-124 414.1 0.8 1.1 1 0 0 1 1 1 1 Calreticulin family Aldedh PF00171.17 CAR26749.1 - 2.5e-181 603.0 0.1 2.8e-181 602.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LRR_4 PF12799.2 CAR26750.1 - 2.5e-18 65.2 36.3 4.9e-05 22.8 0.9 7.6 4 2 2 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAR26750.1 - 5.9e-14 51.5 36.4 9.3e-05 22.1 3.3 6.8 4 2 4 8 8 8 6 Leucine rich repeat LRR_1 PF00560.28 CAR26750.1 - 2e-11 42.2 32.7 0.83 9.9 0.3 10.7 7 2 2 9 9 9 5 Leucine Rich Repeat LRR_6 PF13516.1 CAR26750.1 - 3.7e-06 26.4 27.7 0.81 9.9 0.1 9.3 8 1 0 8 8 8 4 Leucine Rich repeat LRR_7 PF13504.1 CAR26750.1 - 9.5e-06 25.0 32.1 6.8 7.3 0.1 11.2 11 0 0 11 11 11 4 Leucine rich repeat DUF4366 PF14283.1 CAR26750.1 - 0.26 10.6 9.3 0.019 14.3 1.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) DivIC PF04977.10 CAR26751.1 - 2.2 7.8 7.5 6.3 6.3 5.2 1.7 1 0 0 1 1 1 0 Septum formation initiator Kelch_6 PF13964.1 CAR26752.1 - 1.1e-10 41.2 10.1 0.0048 17.0 0.0 6.8 7 0 0 7 7 7 3 Kelch motif Kelch_5 PF13854.1 CAR26752.1 - 6.1e-09 35.6 6.1 0.15 12.0 0.0 6.5 7 0 0 7 7 7 2 Kelch motif Kelch_3 PF13415.1 CAR26752.1 - 6.9e-09 35.6 3.8 0.00054 20.0 0.0 4.4 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CAR26752.1 - 2.1e-07 30.4 14.5 0.031 14.0 0.1 6.8 7 0 0 7 7 7 2 Kelch motif Kelch_4 PF13418.1 CAR26752.1 - 1.1e-06 28.3 16.8 0.0013 18.4 0.0 5.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.20 CAR26752.1 - 5.9e-06 25.7 17.0 0.065 12.7 0.0 5.1 5 0 0 5 5 5 3 Kelch motif ABM PF03992.11 CAR26752.1 - 0.11 12.5 0.4 0.2 11.7 0.3 1.4 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase Bax1-I PF01027.15 CAR26752.1 - 0.35 10.4 0.5 0.83 9.2 0.0 1.7 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 GDI PF00996.13 CAR26753.1 - 1.9e-56 191.2 0.0 2.5e-56 190.8 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor FAD_binding_3 PF01494.14 CAR26753.1 - 0.014 14.5 0.1 0.037 13.0 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.1 CAR26753.1 - 0.022 14.7 0.0 0.054 13.5 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Ribosomal_L7Ae PF01248.21 CAR26754.1 - 2.4e-21 75.0 0.4 3e-21 74.7 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1269 PF06897.7 CAR26754.1 - 0.0013 18.7 0.2 0.0023 17.9 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1269) Rad1 PF02144.11 CAR26755.1 - 6.3e-62 208.8 0.5 9.3e-62 208.2 0.4 1.3 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Peroxin-22 PF12827.2 CAR26756.1 - 5.9e-32 109.8 0.0 7.5e-32 109.4 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis protein family DUF3918 PF13056.1 CAR26756.1 - 0.29 10.5 1.5 0.48 9.7 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) CH PF00307.26 CAR26757.1 - 4.1e-11 42.8 0.0 6.1e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain AMP-binding PF00501.23 CAR26758.1 - 1e-92 310.7 0.1 1.3e-92 310.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CAR26758.1 - 1.1e-18 67.9 0.1 1.6e-17 64.1 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain TRP PF06011.7 CAR26759.1 - 1.8e-157 524.4 34.7 2.3e-157 524.0 24.1 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 CAR26759.1 - 4.6e-42 143.4 1.5 7.6e-42 142.6 1.0 1.4 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.10 CAR26759.1 - 0.00021 21.5 0.1 0.00041 20.6 0.0 1.4 1 0 0 1 1 1 1 ML domain DUF1296 PF06972.6 CAR26759.1 - 0.1 12.5 0.2 0.24 11.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) Zn_clus PF00172.13 CAR26760.1 - 6.3e-10 38.8 10.2 9.9e-10 38.1 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DLH PF01738.13 CAR26761.1 - 3.4e-29 101.6 0.0 4.1e-29 101.4 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 CAR26761.1 - 0.00021 21.0 0.0 0.00029 20.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 CAR26761.1 - 0.11 12.1 0.0 0.27 10.7 0.0 1.6 1 1 1 2 2 2 0 alpha/beta hydrolase fold Miro PF08477.8 CAR26762.1 - 1.4e-43 148.1 0.0 4.1e-21 75.6 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein EF_assoc_1 PF08355.7 CAR26762.1 - 3.3e-28 96.7 0.5 6.7e-28 95.7 0.3 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_2 PF08356.7 CAR26762.1 - 3.7e-28 97.1 0.0 8.7e-28 95.9 0.0 1.6 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 CAR26762.1 - 4.7e-25 87.8 0.0 6e-12 45.2 0.0 2.8 2 1 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 CAR26762.1 - 4.9e-08 32.9 0.0 0.00029 20.7 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Arf PF00025.16 CAR26762.1 - 5.1e-08 32.3 0.0 3e-05 23.3 0.0 2.8 3 0 0 3 3 3 1 ADP-ribosylation factor family EF-hand_7 PF13499.1 CAR26762.1 - 7.8e-05 22.7 1.3 0.11 12.5 0.2 3.0 3 0 0 3 3 2 2 EF-hand domain pair Dynamin_N PF00350.18 CAR26762.1 - 0.00016 21.5 0.2 0.0092 15.8 0.0 2.5 2 0 0 2 2 2 1 Dynamin family EF-hand_1 PF00036.27 CAR26762.1 - 0.00017 20.6 6.7 0.097 12.0 0.6 3.3 3 0 0 3 3 2 2 EF hand EF-hand_8 PF13833.1 CAR26762.1 - 0.00028 20.4 1.5 0.097 12.2 0.8 2.6 2 0 0 2 2 2 1 EF-hand domain pair GTP_EFTU PF00009.22 CAR26762.1 - 0.00075 18.9 0.0 1.2 8.5 0.0 3.6 4 0 0 4 4 4 1 Elongation factor Tu GTP binding domain MobB PF03205.9 CAR26762.1 - 0.00084 19.0 0.1 0.86 9.3 0.1 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B EF-hand_6 PF13405.1 CAR26762.1 - 0.00094 18.8 3.4 0.8 9.7 0.3 3.1 2 0 0 2 2 2 2 EF-hand domain AAA_24 PF13479.1 CAR26762.1 - 0.001 18.6 0.0 0.087 12.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CAR26762.1 - 0.0014 18.6 0.0 0.51 10.2 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CAR26762.1 - 0.0041 17.2 0.0 1.9 8.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain FeoB_N PF02421.13 CAR26762.1 - 0.0047 16.2 0.0 3.2 7.0 0.0 3.3 3 0 0 3 3 3 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 CAR26762.1 - 0.0053 15.9 0.0 0.13 11.3 0.0 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 CAR26762.1 - 0.018 14.5 0.0 3.7 7.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Septin PF00735.13 CAR26762.1 - 0.024 13.6 0.0 0.9 8.5 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_18 PF13238.1 CAR26762.1 - 0.028 14.7 0.1 16 5.7 0.0 3.7 3 1 0 3 3 3 0 AAA domain DUF258 PF03193.11 CAR26762.1 - 0.034 13.3 0.0 0.23 10.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 CAR26762.1 - 0.055 12.8 0.0 1.3 8.4 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain EF-hand_5 PF13202.1 CAR26762.1 - 0.068 12.5 5.6 0.14 11.5 1.0 3.0 2 0 0 2 2 2 0 EF hand AAA_32 PF13654.1 CAR26762.1 - 0.097 11.3 0.1 0.38 9.3 0.0 1.9 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.13 CAR26762.1 - 0.15 11.4 0.0 1.8 7.9 0.0 2.5 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_33 PF13671.1 CAR26762.1 - 0.17 11.7 0.0 15 5.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Proteasome PF00227.21 CAR26763.1 - 2.5e-52 176.9 0.0 3.5e-52 176.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CAR26763.1 - 1.8e-11 43.1 0.0 1.8e-11 43.1 0.0 2.0 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature DUF2457 PF10446.4 CAR26763.1 - 8.5 4.9 10.1 11 4.6 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Mto2_bdg PF12808.2 CAR26764.1 - 5.2e-07 29.6 6.8 5.2e-07 29.6 4.7 4.7 4 0 0 4 4 4 1 Micro-tubular organiser Mto1 C-term Mto2-binding region bZIP_2 PF07716.10 CAR26764.1 - 0.013 15.3 3.0 0.013 15.3 2.1 6.3 4 1 2 6 6 6 0 Basic region leucine zipper NYD-SP28_assoc PF14775.1 CAR26764.1 - 0.044 13.4 14.0 0.26 11.0 3.0 4.3 3 0 0 3 3 3 0 Sperm tail C-terminal domain Na_K-ATPase PF00287.13 CAR26764.1 - 0.81 8.4 6.8 3.8 6.2 0.8 2.9 1 1 2 3 3 3 0 Sodium / potassium ATPase beta chain eIF2A PF08662.6 CAR26765.1 - 7.9e-26 90.9 3.6 8.1e-23 81.1 0.4 4.1 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 CAR26765.1 - 3.6e-08 32.9 0.1 8.3e-08 31.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR26765.1 - 0.00012 21.9 0.0 0.00036 20.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR26765.1 - 0.0031 17.3 0.0 0.0075 16.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 CAR26765.1 - 0.03 14.2 2.1 88 3.2 0.0 5.4 5 0 0 5 5 5 0 WD domain, G-beta repeat BolA PF01722.13 CAR26766.1 - 2.7e-17 62.4 0.0 3.9e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 BolA-like protein BolA PF01722.13 CAR26767.1 - 4.2e-24 84.2 0.2 5.2e-24 84.0 0.1 1.1 1 0 0 1 1 1 1 BolA-like protein GCV_H PF01597.14 CAR26768.1 - 1.3e-42 144.2 0.2 1.6e-42 144.0 0.1 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein MBF1 PF08523.5 CAR26769.1 - 8.6e-26 89.7 1.1 1.9e-25 88.6 0.7 1.6 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 CAR26769.1 - 1.5e-13 50.3 0.3 2.6e-13 49.6 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 CAR26769.1 - 3.1e-05 24.0 0.0 6.7e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 CAR26769.1 - 0.0016 18.4 0.1 0.003 17.5 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain DBP PF12361.3 CAR26769.1 - 0.051 13.1 1.4 0.06 12.8 0.9 1.1 1 0 0 1 1 1 0 Duffy-antigen binding protein TRAP-gamma PF07074.7 CAR26769.1 - 0.3 10.5 0.9 0.41 10.1 0.6 1.2 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) LRR_6 PF13516.1 CAR26770.1 - 6.1e-12 44.3 13.3 0.097 12.7 0.0 7.6 7 0 0 7 7 7 5 Leucine Rich repeat LRR_4 PF12799.2 CAR26770.1 - 1.2e-08 34.3 25.9 0.079 12.6 1.5 6.6 5 2 3 8 8 8 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CAR26770.1 - 6.3e-07 28.5 15.8 3.7 7.9 0.0 7.5 7 1 0 7 7 7 4 Leucine Rich Repeat LRR_8 PF13855.1 CAR26770.1 - 9.7e-06 25.2 17.9 0.54 10.0 1.1 5.4 4 1 0 4 4 4 4 Leucine rich repeat LRR_7 PF13504.1 CAR26770.1 - 1.6e-05 24.3 13.4 10 6.8 0.0 7.4 7 0 0 7 7 7 1 Leucine rich repeat OHA PF14418.1 CAR26771.1 - 0.0044 16.4 0.6 0.29 10.6 0.0 2.7 2 1 0 2 2 2 2 OST-HTH Associated domain Acyltransferase PF01553.16 CAR26771.1 - 0.1 12.0 0.1 0.48 9.8 0.1 2.1 1 1 0 1 1 1 0 Acyltransferase CybS PF05328.7 CAR26772.1 - 1.6e-51 173.3 0.0 1.9e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 CybS RNase_H PF00075.19 CAR26773.1 - 5.7e-27 94.6 0.3 1.6e-26 93.2 0.0 1.8 2 0 0 2 2 2 1 RNase H Cauli_VI PF01693.11 CAR26773.1 - 4.4e-26 90.6 3.4 1.3e-18 66.7 0.4 2.6 2 0 0 2 2 2 2 Caulimovirus viroplasmin Bul1_N PF04425.7 CAR26774.1 - 3.6e-50 170.8 1.0 3.7e-48 164.1 0.7 2.2 1 1 0 1 1 1 1 Bul1 N terminus Bul1_C PF04426.7 CAR26774.1 - 2.5e-32 112.1 2.5 2.2e-16 59.8 0.4 2.4 1 1 1 2 2 2 2 Bul1 C terminus Proteasome PF00227.21 CAR26775.1 - 1.8e-47 161.0 0.0 2.2e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CAR26775.1 - 1e-12 47.1 0.2 1.9e-12 46.2 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3336 PF11815.3 CAR26776.1 - 8.2e-28 96.7 0.1 1.8e-27 95.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 CAR26776.1 - 1.2e-08 35.1 0.0 2.3e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase DUF2348 PF09807.4 CAR26777.1 - 0.0013 17.8 0.0 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) Tautomerase PF01361.16 CAR26777.1 - 0.0026 17.3 0.0 0.0061 16.1 0.0 1.7 1 0 0 1 1 1 1 Tautomerase enzyme DnaJ PF00226.26 CAR26778.1 - 3.7e-16 58.6 0.8 3.7e-16 58.6 0.5 2.8 3 1 0 3 3 3 1 DnaJ domain SURF4 PF02077.10 CAR26779.1 - 3.2e-102 341.4 10.6 3.7e-102 341.2 7.4 1.0 1 0 0 1 1 1 1 SURF4 family IPP-2 PF04979.9 CAR26780.1 - 7.5e-13 48.8 13.0 7.5e-13 48.8 9.0 1.8 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) Peptidase_C37 PF05416.7 CAR26780.1 - 0.4 8.9 5.9 0.47 8.6 4.1 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Sigma70_ner PF04546.8 CAR26780.1 - 1.1 8.8 11.4 1.5 8.3 7.6 1.5 1 1 0 1 1 1 0 Sigma-70, non-essential region Methyltrn_RNA_3 PF02598.12 CAR26781.1 - 1.4e-90 303.5 0.1 1.7e-90 303.3 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase MVIN PF03023.9 CAR26781.1 - 0.092 11.1 0.0 0.13 10.6 0.0 1.1 1 0 0 1 1 1 0 MviN-like protein Glyco_hydro_17 PF00332.13 CAR26782.1 - 7.2e-67 225.6 2.1 8.2e-67 225.4 1.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 eIF-3c_N PF05470.7 CAR26783.1 - 2.6e-161 537.7 13.3 1.8e-123 412.7 1.2 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 CAR26783.1 - 8.1e-13 48.6 0.3 5.4e-12 45.9 0.2 2.5 1 1 0 1 1 1 1 PCI domain DUF1548 PF07579.6 CAR26783.1 - 0.9 9.6 6.8 1.1 9.4 0.2 3.7 3 1 0 3 3 3 0 Domain of Unknown Function (DUF1548) HEAT_EZ PF13513.1 CAR26784.1 - 1.2e-19 70.1 9.1 2.1e-06 28.0 0.0 10.8 9 2 2 11 11 11 5 HEAT-like repeat HEAT_2 PF13646.1 CAR26784.1 - 2.8e-18 65.9 0.7 5.7e-07 29.7 0.0 5.9 5 1 1 6 6 6 4 HEAT repeats HEAT PF02985.17 CAR26784.1 - 2.6e-14 51.9 17.3 0.0074 16.2 0.0 10.6 12 0 0 12 12 12 4 HEAT repeat MMS19_C PF12460.3 CAR26784.1 - 5.4e-08 31.9 4.6 0.00014 20.7 0.5 3.7 4 1 0 4 4 4 2 RNAPII transcription regulator C-terminal RIX1 PF08167.7 CAR26784.1 - 1.5e-06 28.0 0.4 0.013 15.1 0.0 5.7 5 1 1 6 6 6 1 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.2 CAR26784.1 - 5.1e-06 26.7 0.1 0.045 14.1 0.0 4.9 2 1 2 5 5 5 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 CAR26784.1 - 8.3e-05 22.0 0.1 0.045 13.0 0.2 3.8 3 0 0 3 3 3 1 CLASP N terminal Arm PF00514.18 CAR26784.1 - 0.00015 21.4 4.9 3.1 7.7 0.0 6.5 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat EST1_DNA_bind PF10373.4 CAR26784.1 - 0.0049 16.1 0.1 0.017 14.3 0.0 2.0 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain DnaJ-X PF14308.1 CAR26784.1 - 0.054 12.7 0.0 1.7 7.8 0.0 2.4 2 0 0 2 2 2 0 X-domain of DnaJ-containing MFS_1 PF07690.11 CAR26785.1 - 1.4e-49 168.7 39.5 2.4e-49 167.9 27.1 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 CAR26785.1 - 6.4e-15 54.3 8.9 8.7e-15 53.9 6.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 CAR26785.1 - 2.3e-14 52.8 11.7 2.3e-14 52.8 8.1 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter GNVR PF13807.1 CAR26785.1 - 0.089 12.5 0.0 0.29 10.8 0.0 1.8 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase Sulfate_transp PF00916.15 CAR26786.1 - 4.1e-78 262.2 3.0 7.9e-78 261.2 2.1 1.5 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CAR26786.1 - 7e-31 105.7 2.3 7e-31 105.7 1.6 2.4 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 CAR26786.1 - 0.015 14.7 0.0 0.032 13.6 0.0 1.5 1 0 0 1 1 1 0 STAS domain Apc4 PF12896.2 CAR26787.1 - 7.6e-21 74.3 0.2 7.6e-21 74.3 0.1 2.4 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 4 SUI1 PF01253.17 CAR26788.1 - 3.6e-11 42.7 0.0 1e-10 41.2 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor SUI1 SWIB PF02201.13 CAR26788.1 - 3.9e-05 23.2 0.4 8.6e-05 22.1 0.3 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain Ribosomal_L1 PF00687.16 CAR26789.1 - 3.6e-19 68.9 0.0 4.9e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ribosomal_L34 PF00468.12 CAR26790.1 - 8.5e-17 60.5 10.7 1.4e-16 59.8 7.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L34 Securin PF04856.8 CAR26792.1 - 1.8e-24 86.7 10.1 3e-24 86.0 7.0 1.4 1 0 0 1 1 1 1 Securin sister-chromatid separation inhibitor DnaJ PF00226.26 CAR26793.1 - 5.6e-26 90.0 1.0 8.9e-26 89.4 0.7 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CAR26793.1 - 1.6e-20 72.7 0.4 6.5e-16 58.0 0.0 3.4 3 1 1 4 4 4 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CAR26793.1 - 1.1e-10 41.4 19.3 1.2e-08 34.8 14.0 3.0 1 1 2 3 3 3 3 DnaJ central domain Cytochrome_C7 PF14522.1 CAR26793.1 - 0.0035 16.9 6.9 0.0054 16.3 2.7 2.3 2 0 0 2 2 2 1 Cytochrome c7 Cytochrom_c3_2 PF14537.1 CAR26793.1 - 0.0078 16.5 8.8 0.045 14.0 2.4 2.4 1 1 1 2 2 2 2 Cytochrome c3 Cytochrome_C554 PF13435.1 CAR26793.1 - 0.036 14.1 7.8 0.11 12.5 5.4 1.8 1 1 0 1 1 1 0 Cytochrome c554 and c-prime zf-CHY PF05495.7 CAR26793.1 - 2.4 8.3 10.6 41 4.4 0.6 2.3 1 1 1 2 2 2 0 CHY zinc finger Zn_Tnp_IS1595 PF12760.2 CAR26793.1 - 8.3 6.3 13.4 1.9 8.3 1.3 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Aminotran_1_2 PF00155.16 CAR26794.1 - 8.9e-37 126.8 0.0 1.3e-36 126.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CAR26794.1 - 0.0023 17.1 0.0 0.0059 15.7 0.0 1.6 2 0 0 2 2 2 1 Beta-eliminating lyase rve PF00665.21 CAR26795.1 - 0.021 14.9 0.0 0.045 13.8 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain Gaa1 PF04114.9 CAR26796.1 - 1.1e-117 393.8 19.5 2.3e-113 379.6 5.6 2.1 1 1 1 2 2 2 2 Gaa1-like, GPI transamidase component SMC_N PF02463.14 CAR26798.1 - 4.4e-64 215.7 58.1 3.4e-63 212.8 40.3 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CAR26798.1 - 1.8e-27 95.7 0.0 5.4e-27 94.1 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CAR26798.1 - 1.6e-08 34.9 13.8 2.9e-06 27.4 0.0 5.7 2 2 1 4 4 4 2 AAA domain AAA_29 PF13555.1 CAR26798.1 - 0.0003 20.2 0.0 0.00062 19.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 CAR26798.1 - 0.12 11.7 8.4 1.7 8.1 0.0 4.2 4 1 0 4 4 4 0 FtsK/SpoIIIE family MtrG PF04210.8 CAR26798.1 - 0.13 11.9 2.8 3.7 7.3 0.2 3.9 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G WEMBL PF05701.6 CAR26798.1 - 0.47 8.8 111.2 0.0065 14.9 25.5 5.3 3 2 2 5 5 5 0 Weak chloroplast movement under blue light Actin PF00022.14 CAR26799.1 - 2.8e-52 177.4 0.0 3.4e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 Actin FGGY_C PF02782.11 CAR26800.1 - 1.3e-49 168.5 0.1 2.2e-49 167.7 0.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 CAR26800.1 - 3.1e-23 82.3 0.0 3.8e-22 78.7 0.0 2.3 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Rax2 PF12768.2 CAR26801.1 - 5e-50 170.2 3.4 5e-50 170.2 2.4 4.0 4 1 0 4 4 4 2 Cortical protein marker for cell polarity TRAPPC-Trs85 PF12739.2 CAR26802.1 - 2.9e-99 332.5 0.5 4.2e-99 332.0 0.3 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit EMP70 PF02990.11 CAR26803.1 - 2.6e-207 689.4 10.7 3.9e-207 688.8 7.4 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 DUF2205 PF10224.4 CAR26804.1 - 8.1e-08 31.7 1.4 8.1e-08 31.7 0.9 1.7 2 0 0 2 2 2 1 Predicted coiled-coil protein (DUF2205) DUF972 PF06156.8 CAR26804.1 - 1.1 9.6 4.1 3.8 7.9 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Takusan PF04822.8 CAR26805.1 - 0.62 9.8 2.4 0.57 9.9 0.1 2.1 3 0 0 3 3 3 0 Takusan Serinc PF03348.10 CAR26806.1 - 3e-146 487.5 11.3 3.4e-146 487.3 7.9 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Rad51 PF08423.6 CAR26807.1 - 3e-124 412.9 0.1 4.7e-124 412.3 0.1 1.3 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 CAR26807.1 - 3.2e-10 39.7 0.0 4.8e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 CAR26807.1 - 9.3e-10 38.0 0.1 1.3e-09 37.6 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 CAR26807.1 - 9.2e-08 31.4 0.8 2.9e-07 29.8 0.1 2.2 2 1 0 2 2 2 1 KaiC HHH_5 PF14520.1 CAR26807.1 - 2e-06 27.8 0.1 5.1e-06 26.5 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain PAXNEB PF05625.6 CAR26807.1 - 0.0091 14.8 0.1 0.086 11.6 0.1 2.0 2 0 0 2 2 2 1 PAXNEB protein RNA_pol_A_CTD PF03118.10 CAR26807.1 - 0.045 13.1 0.1 0.092 12.1 0.1 1.5 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain PH_4 PF15404.1 CAR26808.1 - 5.7e-74 247.6 0.1 1.5e-73 246.3 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Spo7_2_N PF15407.1 CAR26808.1 - 1.5e-25 88.4 0.1 4.1e-25 87.0 0.0 1.8 1 0 0 1 1 1 1 Sporulation protein family 7 PH PF00169.24 CAR26808.1 - 4.4e-07 30.0 1.8 0.027 14.6 0.2 4.4 3 2 0 3 3 3 2 PH domain Ste5_C PF12194.3 CAR26809.1 - 2e-74 249.4 0.1 3.2e-74 248.7 0.1 1.3 1 0 0 1 1 1 1 Protein kinase Fus3-binding zf-RING_2 PF13639.1 CAR26809.1 - 3.2e-05 23.6 2.5 6e-05 22.7 1.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CAR26809.1 - 0.18 11.5 3.4 0.67 9.7 2.4 2.0 1 1 0 1 1 1 0 zinc-RING finger domain E1_dh PF00676.15 CAR26810.1 - 1.6e-117 391.5 0.1 2e-117 391.2 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 CAR26810.1 - 0.0018 17.2 0.0 0.0032 16.4 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Cyclin_N PF00134.18 CAR26811.1 - 9.4e-20 70.4 0.0 1.7e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 CAR26811.1 - 9.2e-12 45.6 0.0 1.6e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Cyclin DNA_pol3_delta2 PF13177.1 CAR26812.1 - 1.3e-18 67.2 0.2 9.5e-16 57.8 0.0 3.0 2 1 0 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.24 CAR26812.1 - 3.8e-17 62.7 0.0 7.2e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 CAR26812.1 - 1e-14 54.2 0.0 2.1e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_22 PF13401.1 CAR26812.1 - 9.6e-08 32.2 0.9 0.012 15.7 0.1 3.0 2 1 1 3 3 3 2 AAA domain Rad17 PF03215.10 CAR26812.1 - 2.4e-07 29.8 0.0 1.1e-06 27.6 0.0 2.1 1 1 1 2 2 2 1 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 CAR26812.1 - 1.1e-06 27.8 0.0 2.4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DNA_pol3_delta PF06144.8 CAR26812.1 - 1.6e-06 27.7 0.1 3.6e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.1 CAR26812.1 - 2.2e-06 27.7 0.2 4e-05 23.6 0.1 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 CAR26812.1 - 1.1e-05 25.3 0.0 2.3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 CAR26812.1 - 7.1e-05 21.8 0.0 0.00031 19.7 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 CAR26812.1 - 0.00052 19.4 0.0 0.0013 18.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_11 PF13086.1 CAR26812.1 - 0.00055 19.5 0.1 0.0019 17.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 CAR26812.1 - 0.00066 19.2 0.1 0.015 14.8 0.0 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_19 PF13245.1 CAR26812.1 - 0.0012 18.5 0.0 0.003 17.2 0.0 1.7 1 1 0 1 1 1 1 Part of AAA domain AAA_10 PF12846.2 CAR26812.1 - 0.0023 17.4 0.4 0.92 8.8 0.0 2.4 1 1 1 2 2 2 1 AAA-like domain TIP49 PF06068.8 CAR26812.1 - 0.0023 16.7 0.0 0.1 11.3 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus ResIII PF04851.10 CAR26812.1 - 0.0028 17.5 0.1 0.072 12.9 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_5 PF07728.9 CAR26812.1 - 0.0028 17.3 0.0 0.014 15.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CAR26812.1 - 0.0037 16.6 1.3 0.14 11.5 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_17 PF13207.1 CAR26812.1 - 0.0046 17.7 0.0 0.013 16.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CAR26812.1 - 0.0069 15.9 0.3 0.21 11.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 CAR26812.1 - 0.0085 15.6 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 CAR26812.1 - 0.0094 15.6 0.1 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase PhoH PF02562.11 CAR26812.1 - 0.012 14.8 0.1 1.8 7.7 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_3 PF07726.6 CAR26812.1 - 0.015 14.9 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 CAR26812.1 - 0.019 14.5 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 CAR26812.1 - 0.022 13.9 0.0 0.12 11.4 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 CAR26812.1 - 0.023 14.9 0.0 0.057 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CAR26812.1 - 0.029 14.5 0.1 0.08 13.1 0.0 1.9 2 1 0 2 2 1 0 RNA helicase AAA_33 PF13671.1 CAR26812.1 - 0.041 13.7 0.1 0.13 12.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 CAR26812.1 - 0.051 13.5 0.0 0.12 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain NYD-SP12_N PF15015.1 CAR26812.1 - 0.074 11.2 0.1 0.11 10.7 0.0 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal DUF2075 PF09848.4 CAR26812.1 - 0.088 11.7 0.0 0.31 9.9 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mid1 PF12929.2 CAR26813.1 - 2.7e-138 461.2 12.2 3.5e-138 460.9 8.5 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 CAR26813.1 - 0.072 13.4 2.2 1.7 9.0 0.2 2.6 2 0 0 2 2 2 0 Fz domain TruB_N PF01509.13 CAR26814.1 - 1.5e-41 141.9 5.0 1.3e-39 135.7 0.1 3.2 3 0 0 3 3 3 2 TruB family pseudouridylate synthase (N terminal domain) Erf4 PF10256.4 CAR26815.1 - 2.8e-28 98.1 0.0 3.7e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family ubiquitin PF00240.18 CAR26816.1 - 6.6e-07 28.6 0.1 1.3e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CAR26816.1 - 0.00011 21.8 0.1 0.00022 20.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 CAR26816.1 - 0.00037 20.3 0.1 0.0009 19.1 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CLU_N PF15044.1 CAR26816.1 - 0.032 14.3 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial function, CLU-N-term RabGAP-TBC PF00566.13 CAR26817.1 - 1.6e-45 155.1 1.5 4.8e-45 153.6 1.1 1.8 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PalH PF08733.5 CAR26818.1 - 3.1e-84 282.8 7.0 3.6e-84 282.5 4.8 1.1 1 0 0 1 1 1 1 PalH/RIM21 Pet20 PF08692.5 CAR26819.1 - 1.1e-12 48.0 1.9 1.3e-12 47.7 0.0 2.1 2 1 1 3 3 3 1 Mitochondrial protein Pet20 Sec7_N PF12783.2 CAR26820.1 - 3.1e-37 127.5 5.7 3.1e-37 127.5 4.0 4.6 5 0 0 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Pkinase PF00069.20 CAR26821.1 - 5.6e-66 222.3 0.0 1e-65 221.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR26821.1 - 2.4e-50 171.0 0.0 4.1e-50 170.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 CAR26821.1 - 6e-22 77.8 0.3 3.1e-21 75.5 0.2 2.4 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.24 CAR26821.1 - 3.9e-11 43.0 0.0 1e-10 41.7 0.0 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 CAR26821.1 - 3.5e-06 26.1 0.0 6.2e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.1 CAR26821.1 - 0.013 15.7 0.4 0.074 13.3 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain APH PF01636.18 CAR26821.1 - 0.018 14.8 0.1 0.048 13.3 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 CAR26821.1 - 0.081 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RF-1 PF00472.15 CAR26822.1 - 1.7e-14 53.5 0.3 2.6e-14 52.9 0.2 1.3 1 0 0 1 1 1 1 RF-1 domain NTP_transf_2 PF01909.18 CAR26823.1 - 1.5e-15 57.2 0.0 5.5e-15 55.4 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 CAR26823.1 - 5.8e-12 45.3 0.0 1.3e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase DNA_pol_B_palm PF14792.1 CAR26823.1 - 0.024 14.7 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase beta palm ADK PF00406.17 CAR26824.1 - 1.3e-59 200.4 0.0 1.5e-59 200.1 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 CAR26824.1 - 2.6e-15 55.7 0.0 6.5e-15 54.4 0.0 1.7 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.1 CAR26824.1 - 4e-07 30.0 0.0 6.6e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CAR26824.1 - 0.00021 22.1 0.0 0.00031 21.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CAR26824.1 - 0.00041 20.6 0.0 0.00075 19.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 CAR26824.1 - 0.019 14.3 0.1 0.051 12.9 0.0 1.7 1 1 1 2 2 2 0 Thymidylate kinase Zeta_toxin PF06414.7 CAR26824.1 - 0.034 13.2 0.1 0.067 12.2 0.0 1.6 2 1 0 2 2 2 0 Zeta toxin GCR1_C PF12550.3 CAR26825.1 - 4.3e-25 87.3 0.5 7.5e-25 86.6 0.4 1.4 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes DUF605 PF04652.11 CAR26825.1 - 0.0013 18.2 23.7 0.0016 17.8 16.4 1.1 1 0 0 1 1 1 1 Vta1 like Tropomyosin PF00261.15 CAR26825.1 - 0.0041 16.2 0.5 0.0041 16.2 0.3 1.5 2 0 0 2 2 2 1 Tropomyosin PAT1 PF09770.4 CAR26825.1 - 0.05 11.8 23.0 0.052 11.7 15.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ndc1_Nup PF09531.5 CAR26825.1 - 0.28 9.5 4.9 0.34 9.2 3.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIA PF03153.8 CAR26825.1 - 0.39 10.5 17.5 0.46 10.3 12.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4106 PF13388.1 CAR26825.1 - 0.85 8.5 13.7 1.1 8.2 9.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) CAF-1_p150 PF11600.3 CAR26825.1 - 1.9 7.8 9.4 3 7.1 6.5 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal YlbD_coat PF14071.1 CAR26827.1 - 0.045 13.8 0.1 0.15 12.1 0.1 1.9 1 0 0 1 1 1 0 Putative coat protein PCI PF01399.22 CAR26827.1 - 1.4 9.2 7.7 0.77 10.1 0.8 3.4 2 1 2 4 4 4 0 PCI domain Redoxin PF08534.5 CAR26828.1 - 4.2e-29 100.9 0.0 5.1e-29 100.7 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 CAR26828.1 - 2.7e-08 33.5 0.0 3.5e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family MFS_1 PF07690.11 CAR26829.1 - 8.4e-30 103.6 36.6 8.4e-30 103.6 25.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 CAR26830.1 - 1.2e-28 99.8 37.0 1.2e-28 99.8 25.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_L18e PF00828.14 CAR26831.1 - 5e-24 85.1 0.3 7.6e-24 84.5 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Ribosomal_S19e PF01090.14 CAR26832.1 - 1.8e-55 186.2 0.1 1.9e-55 186.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Nramp PF01566.13 CAR26833.1 - 1.6e-88 296.8 13.1 3e-88 296.0 9.0 1.4 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein RNA12 PF10443.4 CAR26833.1 - 0.022 13.2 0.0 0.036 12.5 0.0 1.2 1 0 0 1 1 1 0 RNA12 protein RRM_1 PF00076.17 CAR26834.1 - 5e-37 125.3 1.1 8.7e-20 70.1 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR26834.1 - 1.4e-32 111.4 0.1 4.3e-16 58.6 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR26834.1 - 6.5e-13 48.3 0.0 7.9e-06 25.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 CAR26834.1 - 0.0088 15.5 0.2 4.7 6.8 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease B OB domain UPF0020 PF01170.13 CAR26835.1 - 8.6e-15 54.7 0.0 1.8e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 CAR26835.1 - 1.7e-07 31.2 0.0 3.1e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 CAR26835.1 - 0.001 18.6 0.1 0.035 13.6 0.0 2.4 2 1 0 2 2 2 1 DNA methylase MethyltransfD12 PF02086.10 CAR26835.1 - 0.0082 15.6 1.0 4 6.8 0.0 2.6 2 1 1 3 3 3 2 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_32 PF13679.1 CAR26835.1 - 0.16 11.6 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ras PF00071.17 CAR26836.1 - 5.4e-27 94.1 0.1 3.1e-22 78.7 0.0 2.2 2 0 0 2 2 2 2 Ras family Miro PF08477.8 CAR26836.1 - 4e-11 43.4 0.1 3.2e-09 37.2 0.0 2.3 1 1 0 1 1 1 1 Miro-like protein DUF815 PF05673.8 CAR26836.1 - 6e-06 25.3 0.0 0.02 13.8 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Arf PF00025.16 CAR26836.1 - 2.3e-05 23.7 0.6 0.00014 21.1 0.1 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_5 PF07728.9 CAR26836.1 - 0.0014 18.4 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Gtr1_RagA PF04670.7 CAR26836.1 - 0.027 13.6 0.4 0.15 11.2 0.3 1.9 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_24 PF13479.1 CAR26836.1 - 0.045 13.3 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 CAR26836.1 - 0.071 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 CAR26836.1 - 0.071 11.8 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus AFG1_ATPase PF03969.11 CAR26836.1 - 0.093 11.5 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 AFG1-like ATPase Arch_ATPase PF01637.13 CAR26836.1 - 0.11 12.1 0.0 0.46 10.1 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase TRM13 PF05206.9 CAR26837.1 - 4.7e-82 275.1 0.5 6.2e-82 274.7 0.3 1.1 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-U11-48K PF05253.7 CAR26837.1 - 1.7e-10 40.4 1.6 1.7e-10 40.4 1.1 2.0 2 0 0 2 2 2 1 U11-48K-like CHHC zinc finger zf-TRM13_CCCH PF11722.3 CAR26837.1 - 1.5e-09 37.0 1.2 3.7e-09 35.8 0.9 1.7 1 0 0 1 1 1 1 CCCH zinc finger in TRM13 protein Ldh_1_N PF00056.18 CAR26838.1 - 1.1e-40 138.7 0.2 1.7e-40 138.1 0.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CAR26838.1 - 7.2e-31 107.2 0.0 1e-30 106.7 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Bax1-I PF01027.15 CAR26839.1 - 2.5e-41 141.5 23.7 3e-41 141.2 16.5 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Herpes_BBRF1 PF04793.7 CAR26839.1 - 0.17 10.6 1.4 0.23 10.1 1.0 1.2 1 0 0 1 1 1 0 BRRF1-like protein Lig_chan PF00060.21 CAR26839.1 - 1.1 8.9 6.3 2.3 7.9 4.4 1.5 1 0 0 1 1 1 0 Ligand-gated ion channel Ribosomal_L23eN PF03939.8 CAR26840.1 - 3.4e-20 71.8 10.0 3.4e-20 71.8 7.0 2.3 2 1 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 CAR26840.1 - 5.9e-20 71.0 2.1 5.9e-20 71.0 1.5 1.6 2 0 0 2 2 2 1 Ribosomal protein L23 STN1_2 PF09170.5 CAR26840.1 - 0.048 13.4 0.1 0.064 13.0 0.0 1.2 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 Ribosomal_S11 PF00411.14 CAR26841.1 - 2.8e-05 24.2 0.0 5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S11 Pkinase PF00069.20 CAR26842.1 - 8.7e-56 188.9 0.0 1e-55 188.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR26842.1 - 1.8e-28 99.3 0.0 2.3e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CAR26842.1 - 0.0003 20.6 0.0 0.0013 18.5 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CAR26842.1 - 0.00037 19.5 0.0 0.00058 18.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CAR26842.1 - 0.063 12.3 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UPF0220 PF05255.6 CAR26843.1 - 4.2e-64 214.7 2.7 5.1e-64 214.4 1.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF3169 PF11368.3 CAR26843.1 - 0.53 9.4 2.9 2.9 7.0 0.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3169) Kri1_C PF12936.2 CAR26844.1 - 1.4e-29 101.8 4.7 1.4e-29 101.8 3.3 4.3 3 1 1 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.7 CAR26844.1 - 3.7e-16 59.2 14.2 3.7e-16 59.2 9.9 6.0 4 3 1 5 5 5 1 KRI1-like family CorA PF01544.13 CAR26845.1 - 6.9e-41 140.1 1.9 6.7e-39 133.6 1.3 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein zf-DNL PF05180.7 CAR26847.1 - 2.3e-31 107.3 1.4 3.5e-31 106.7 1.0 1.3 1 0 0 1 1 1 1 DNL zinc finger Elf1 PF05129.8 CAR26847.1 - 0.0023 17.5 0.6 0.0035 17.0 0.4 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-CSL PF05207.8 CAR26847.1 - 0.012 15.0 0.3 0.024 14.1 0.2 1.5 1 0 0 1 1 1 0 CSL zinc finger zinc_ribbon_4 PF13717.1 CAR26847.1 - 0.014 15.1 1.5 0.28 10.9 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CAR26847.1 - 0.017 14.7 1.4 0.29 10.7 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain TFIIS_C PF01096.13 CAR26847.1 - 0.026 14.1 0.7 2.3 7.9 0.1 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Zn-ribbon_8 PF09723.5 CAR26847.1 - 0.54 10.2 3.1 1.4 8.9 2.1 1.7 1 1 0 1 1 1 0 Zinc ribbon domain F-box-like PF12937.2 CAR26848.1 - 3.2e-06 26.7 0.6 1.1e-05 25.0 0.4 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CAR26848.1 - 2.3e-05 23.8 0.2 2.3e-05 23.8 0.2 2.6 2 0 0 2 2 2 1 F-box domain Glyco_hydro_72 PF03198.9 CAR26849.1 - 5.1e-134 446.1 0.8 6.7e-134 445.7 0.6 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 CAR26849.1 - 0.0011 18.1 0.1 0.0043 16.2 0.1 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_cc PF11790.3 CAR26849.1 - 0.039 13.3 0.0 0.059 12.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core tRNA_anti-codon PF01336.20 CAR26850.1 - 2.6e-09 36.8 0.3 6.7e-09 35.4 0.3 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain RPA_C PF08784.6 CAR26850.1 - 2.9e-07 30.8 0.0 2.7e-06 27.7 0.0 2.3 1 1 1 2 2 2 1 Replication protein A C terminal TPR_11 PF13414.1 CAR26851.1 - 4.4e-13 48.6 1.8 2.1e-09 36.8 0.0 4.2 3 2 1 4 4 4 3 TPR repeat TPR_12 PF13424.1 CAR26851.1 - 3.4e-07 30.1 0.0 0.093 12.6 0.0 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 CAR26851.1 - 1.1e-06 28.0 0.3 0.11 12.4 0.0 4.2 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CAR26851.1 - 2.5e-06 27.7 0.8 0.0031 17.8 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 CAR26851.1 - 3.1e-06 26.5 2.1 0.12 12.2 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 CAR26851.1 - 1.4e-05 24.4 0.5 0.81 9.4 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 CAR26851.1 - 1.6e-05 25.1 5.8 0.38 11.5 0.0 6.4 6 2 3 9 9 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 CAR26851.1 - 6.6e-05 23.4 0.4 0.041 14.5 0.0 4.4 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 CAR26851.1 - 0.0057 16.7 0.7 0.17 12.1 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 CAR26851.1 - 0.0072 15.4 0.8 0.52 9.3 0.3 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CAR26851.1 - 0.034 14.2 2.0 1 9.5 0.1 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Clathrin PF00637.15 CAR26851.1 - 0.056 13.0 3.7 0.19 11.3 0.1 2.7 3 0 0 3 3 3 0 Region in Clathrin and VPS Myb_DNA-bind_5 PF13873.1 CAR26852.1 - 2.4e-05 24.1 0.4 8.3e-05 22.4 0.3 1.8 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF2913 PF11140.3 CAR26852.1 - 0.025 13.8 2.1 0.041 13.1 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2913) LIM_bind PF01803.11 CAR26852.1 - 0.91 8.5 5.8 1.8 7.6 4.0 1.4 1 0 0 1 1 1 0 LIM-domain binding protein PAT1 PF09770.4 CAR26852.1 - 1.4 7.0 20.0 1.6 6.8 13.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 CAR26852.1 - 3 7.1 20.9 3.9 6.7 14.5 1.2 1 0 0 1 1 1 0 Vta1 like ATP11 PF06644.6 CAR26853.1 - 1.5e-87 293.5 0.5 1.7e-87 293.3 0.3 1.0 1 0 0 1 1 1 1 ATP11 protein DUF2458 PF10454.4 CAR26853.1 - 0.0089 15.9 1.5 0.017 14.9 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) PDT PF00800.13 CAR26854.1 - 7.9e-55 185.2 0.0 9.9e-55 184.9 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT_5 PF13710.1 CAR26854.1 - 0.09 12.5 0.0 0.35 10.7 0.0 2.0 2 0 0 2 2 2 0 ACT domain ACT PF01842.20 CAR26854.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 ACT domain zf-rbx1 PF12678.2 CAR26855.1 - 9.4e-32 108.9 14.1 1.2e-31 108.6 9.7 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CAR26855.1 - 4.2e-17 61.7 10.5 5.4e-17 61.4 7.3 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 CAR26855.1 - 3.3e-07 30.0 11.7 2.6e-06 27.1 8.1 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CAR26855.1 - 0.0019 17.8 12.0 0.019 14.6 8.3 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAR26855.1 - 0.017 15.1 2.2 0.017 15.1 1.5 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 CAR26855.1 - 0.023 14.2 2.1 0.043 13.3 1.4 1.4 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.1 CAR26855.1 - 0.076 12.7 10.2 2.6 7.7 7.1 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CAR26855.1 - 0.18 11.6 0.4 0.18 11.6 0.3 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CAR26855.1 - 0.21 11.3 6.8 1.7 8.3 4.7 2.5 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.1 CAR26855.1 - 0.7 9.6 10.4 4.6 7.0 7.3 2.3 1 1 1 2 2 2 0 zinc-RING finger domain FANCL_C PF11793.3 CAR26855.1 - 0.92 9.5 9.0 5.5 7.0 6.4 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain Med7 PF05983.6 CAR26856.1 - 2.9e-64 215.7 3.7 3.4e-64 215.5 2.5 1.0 1 0 0 1 1 1 1 MED7 protein MscS_porin PF12795.2 CAR26856.1 - 0.36 10.1 3.6 0.36 10.0 0.3 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain cwf21 PF08312.7 CAR26856.1 - 4.6 7.1 10.0 0.42 10.4 3.0 2.2 2 0 0 2 2 2 0 cwf21 domain 6PF2K PF01591.13 CAR26857.1 - 1.8e-49 167.8 0.5 3.7e-49 166.8 0.3 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 CAR26857.1 - 0.0004 20.2 0.0 0.00096 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 CAR26857.1 - 0.046 12.9 0.2 0.2 10.8 0.0 2.0 2 1 0 2 2 2 0 Chromatin associated protein KTI12 AAA_17 PF13207.1 CAR26857.1 - 0.047 14.5 0.0 0.12 13.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CAR26857.1 - 0.062 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.1 CAR26857.1 - 0.068 13.1 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain tRNA_lig_kinase PF08303.6 CAR26857.1 - 0.1 12.4 0.9 0.49 10.2 0.2 2.1 2 0 0 2 2 2 0 tRNA ligase kinase domain AAA_18 PF13238.1 CAR26857.1 - 0.12 12.6 0.0 0.43 10.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF3399 PF11879.3 CAR26857.1 - 9 6.5 7.3 1.6 8.9 1.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3399) WD40 PF00400.27 CAR26858.1 - 5.3e-43 143.4 11.4 5.9e-10 38.6 0.2 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 CAR26858.1 - 7e-07 29.1 2.3 4.1e-05 23.3 0.8 3.0 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 CAR26858.1 - 0.0022 17.4 0.0 0.18 11.3 0.0 2.8 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.6 CAR26858.1 - 0.0099 14.6 1.4 4.4 5.9 0.2 3.2 1 1 1 3 3 3 2 Nup133 N terminal like MFS_1 PF07690.11 CAR26859.1 - 7.5e-21 74.2 35.4 1.9e-16 59.7 4.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM173 PF15009.1 CAR26859.1 - 1.8 7.2 6.0 1.7 7.3 1.7 2.5 3 0 0 3 3 3 0 Transmembrane protein 173 Sugar_tr PF00083.19 CAR26860.1 - 2.5e-117 392.2 36.3 2.9e-117 392.0 25.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR26860.1 - 7.1e-20 71.0 42.4 1.6e-16 59.9 20.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.27 CAR26861.1 - 8.7e-11 41.2 8.4 1.5e-05 24.6 0.1 4.3 5 0 0 5 5 5 2 WD domain, G-beta repeat zf-rbx1 PF12678.2 CAR26861.1 - 0.0038 17.3 2.3 0.0038 17.3 1.6 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CAR26861.1 - 0.0066 16.2 3.3 0.02 14.7 2.3 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CAR26861.1 - 0.013 15.1 3.9 0.02 14.5 0.3 2.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAR26861.1 - 0.66 10.0 6.5 0.2 11.6 1.7 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Abhydrolase_5 PF12695.2 CAR26862.1 - 1.2e-19 70.4 0.0 1.7e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CAR26862.1 - 3.3e-13 50.0 0.0 5e-11 42.9 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAR26862.1 - 3.6e-11 43.0 0.1 1.6e-05 24.5 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CAR26862.1 - 5.2e-07 29.0 0.0 1.4e-06 27.6 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 CAR26862.1 - 0.00074 19.0 0.1 0.19 11.1 0.0 2.2 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase BAAT_C PF08840.6 CAR26862.1 - 0.00078 19.1 0.0 0.067 12.8 0.0 2.2 1 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.8 CAR26862.1 - 0.0012 18.3 0.0 0.0018 17.7 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.3 CAR26862.1 - 0.0032 17.2 0.0 0.0061 16.3 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DUF829 PF05705.9 CAR26862.1 - 0.008 15.8 0.0 0.87 9.2 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF829) DUF2305 PF10230.4 CAR26862.1 - 0.018 14.4 0.3 2 7.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) UPF0227 PF05728.7 CAR26862.1 - 0.026 14.2 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF818 PF05677.7 CAR26862.1 - 0.051 12.3 0.1 0.081 11.6 0.1 1.3 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) DLH PF01738.13 CAR26862.1 - 0.052 12.8 0.0 6 6.0 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family AXE1 PF05448.7 CAR26862.1 - 0.061 11.8 0.0 0.14 10.5 0.0 1.6 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Esterase PF00756.15 CAR26862.1 - 0.077 12.4 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.20 CAR26862.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) IF4E PF01652.13 CAR26863.1 - 3.9e-56 189.1 0.4 5e-56 188.7 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Na_Ca_ex PF01699.19 CAR26864.1 - 3.9e-31 107.5 21.5 6.3e-18 64.7 6.8 3.6 4 0 0 4 4 4 2 Sodium/calcium exchanger protein DUF307 PF03733.8 CAR26864.1 - 3.5e-12 46.5 7.4 3.5e-12 46.5 5.1 3.5 2 0 0 2 2 2 1 Domain of unknown function (DUF307) Pneumo_phosprot PF02478.11 CAR26865.1 - 0.84 9.1 6.2 1.3 8.4 4.3 1.4 1 0 0 1 1 1 0 Pneumovirus phosphoprotein Aminotran_3 PF00202.16 CAR26866.1 - 4.9e-108 360.9 0.1 5.8e-108 360.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 CAR26866.1 - 3.3e-05 23.0 0.0 5.2e-05 22.3 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Peroxidase_2 PF01328.12 CAR26866.1 - 0.074 11.7 0.0 0.22 10.1 0.0 1.7 2 0 0 2 2 2 0 Peroxidase, family 2 PapC_C PF13953.1 CAR26866.1 - 0.13 11.9 0.2 0.25 10.9 0.2 1.5 1 0 0 1 1 1 0 PapC C-terminal domain CDC50 PF03381.10 CAR26867.1 - 1.1e-86 290.4 0.9 1.5e-86 290.0 0.6 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family PBP1_TM PF14812.1 CAR26867.1 - 2.6 8.4 7.8 2.7 8.3 2.9 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LCM PF04072.9 CAR26868.1 - 5.7e-27 94.4 0.0 9.2e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_6 PF13964.1 CAR26868.1 - 6.1e-17 60.9 0.2 1.7e-07 31.0 0.1 5.1 4 1 1 5 5 5 3 Kelch motif Kelch_4 PF13418.1 CAR26868.1 - 6.8e-17 60.9 0.3 4.3e-11 42.3 0.2 5.3 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_3 PF13415.1 CAR26868.1 - 1.6e-09 37.6 0.1 5.3e-05 23.2 0.1 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 CAR26868.1 - 5.5e-06 25.8 1.3 3.1e-05 23.4 0.1 2.9 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.1 CAR26868.1 - 0.00077 19.3 0.0 2.1 8.4 0.0 4.6 5 0 0 5 5 5 1 Kelch motif Kelch_2 PF07646.10 CAR26868.1 - 0.034 13.9 0.3 0.39 10.5 0.0 3.0 4 0 0 4 4 4 0 Kelch motif Syja_N PF02383.13 CAR26869.1 - 2.8e-95 318.7 0.6 2.8e-95 318.7 0.4 2.1 2 0 0 2 2 2 1 SacI homology domain UBA_e1_C PF09358.5 CAR26870.1 - 0.076 13.1 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-activating enzyme e1 C-terminal domain zf-DHHC PF01529.15 CAR26871.1 - 9.3e-37 126.0 6.5 9.3e-37 126.0 4.5 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase DnaJ PF00226.26 CAR26873.1 - 3.7e-08 32.9 0.0 6.6e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 CAR26873.1 - 0.017 14.9 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Pam16 AAA PF00004.24 CAR26874.1 - 1.4e-54 183.8 0.0 2.5e-43 147.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CAR26874.1 - 4.1e-08 34.0 0.1 0.0053 17.5 0.0 3.3 4 0 0 4 4 2 2 AAA domain AAA_22 PF13401.1 CAR26874.1 - 5.9e-07 29.6 0.1 0.025 14.7 0.0 3.0 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.1 CAR26874.1 - 7.6e-05 22.7 0.3 0.077 12.9 0.0 3.2 2 1 1 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 CAR26874.1 - 0.00015 21.2 0.4 0.0066 15.8 0.1 3.0 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CAR26874.1 - 0.00019 21.5 0.0 0.029 14.5 0.0 2.8 2 0 0 2 2 2 1 RNA helicase RuvB_N PF05496.7 CAR26874.1 - 0.00021 20.4 0.0 0.0012 17.9 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Parvo_NS1 PF01057.12 CAR26874.1 - 0.0004 19.3 0.0 0.0007 18.5 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_14 PF13173.1 CAR26874.1 - 0.0012 18.7 0.0 0.4 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CAR26874.1 - 0.0016 18.7 0.0 0.52 10.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CAR26874.1 - 0.0021 17.8 0.0 0.042 13.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CAR26874.1 - 0.0026 17.6 0.0 0.55 10.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CAR26874.1 - 0.0031 16.9 0.0 0.0068 15.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 CAR26874.1 - 0.011 15.6 0.0 0.079 12.8 0.0 2.3 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 CAR26874.1 - 0.012 15.3 0.0 0.045 13.5 0.0 1.9 2 0 0 2 2 1 0 Part of AAA domain SKI PF01202.17 CAR26874.1 - 0.013 15.3 0.0 3.1 7.6 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase KaiC PF06745.8 CAR26874.1 - 0.018 14.1 0.0 0.035 13.2 0.0 1.4 1 0 0 1 1 1 0 KaiC TIP49 PF06068.8 CAR26874.1 - 0.019 13.7 0.0 0.035 12.8 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 CAR26874.1 - 0.02 14.0 0.1 0.041 13.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CAR26874.1 - 0.035 13.7 0.0 0.74 9.4 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 CAR26874.1 - 0.042 13.0 0.0 0.079 12.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Vps4_C PF09336.5 CAR26874.1 - 0.049 13.5 0.2 0.96 9.3 0.0 2.7 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain PPV_E1_C PF00519.12 CAR26874.1 - 0.051 12.2 0.2 0.71 8.4 0.0 2.1 2 0 0 2 2 2 0 Papillomavirus helicase AAA_24 PF13479.1 CAR26874.1 - 0.065 12.8 0.2 0.17 11.4 0.1 1.8 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.1 CAR26874.1 - 0.073 13.0 0.0 0.58 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Hist_deacetyl PF00850.14 CAR26875.1 - 9.9e-80 268.1 0.0 1.4e-79 267.6 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DMRL_synthase PF00885.14 CAR26876.1 - 5.5e-43 146.0 0.1 6.8e-43 145.7 0.0 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase RRM_5 PF13893.1 CAR26877.1 - 0.00028 20.6 0.8 0.00056 19.7 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAR26877.1 - 0.0057 16.2 2.0 0.0057 16.2 0.2 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Daxx PF03344.10 CAR26877.1 - 1.1 7.6 13.4 1.9 6.8 9.3 1.3 1 0 0 1 1 1 0 Daxx Family TPR_11 PF13414.1 CAR26878.1 - 2.2e-31 107.3 24.2 2.5e-07 30.2 0.1 10.6 6 3 4 11 11 11 7 TPR repeat TPR_12 PF13424.1 CAR26878.1 - 1.4e-24 85.8 21.8 1.5e-06 28.0 0.1 10.2 9 2 2 11 11 11 5 Tetratricopeptide repeat TPR_1 PF00515.23 CAR26878.1 - 7.7e-24 82.2 29.0 3.5e-06 26.3 0.0 11.7 13 0 0 13 13 13 7 Tetratricopeptide repeat TPR_14 PF13428.1 CAR26878.1 - 2.8e-21 74.0 10.6 0.14 12.8 0.1 12.4 9 2 4 13 13 12 5 Tetratricopeptide repeat TPR_2 PF07719.12 CAR26878.1 - 5.8e-21 72.6 34.4 0.0003 20.4 0.0 12.8 15 1 1 16 16 13 6 Tetratricopeptide repeat TPR_19 PF14559.1 CAR26878.1 - 1.9e-19 69.7 7.6 0.0047 17.2 0.0 10.2 9 2 1 10 10 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 CAR26878.1 - 3.5e-18 65.7 10.7 1.3e-05 25.7 0.0 9.3 10 0 0 10 10 10 3 Tetratricopeptide repeat Apc3 PF12895.2 CAR26878.1 - 1.6e-17 63.4 14.6 7.1e-05 22.8 0.1 7.7 5 3 4 9 9 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CAR26878.1 - 1.2e-14 52.8 31.8 2.9e-05 23.5 0.0 11.9 12 1 0 12 12 11 3 Tetratricopeptide repeat TPR_6 PF13174.1 CAR26878.1 - 1e-11 44.4 21.7 0.23 12.0 0.0 11.3 12 0 0 12 12 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 CAR26878.1 - 8.8e-09 34.8 10.9 5.5 7.4 0.0 11.6 12 0 0 12 12 12 1 Tetratricopeptide repeat TPR_7 PF13176.1 CAR26878.1 - 1.8e-08 33.5 11.1 2.4 8.1 0.0 9.7 10 0 0 10 10 10 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CAR26878.1 - 5.9e-06 26.0 2.4 1.6 8.6 0.0 6.4 7 0 0 7 7 6 1 Fis1 C-terminal tetratricopeptide repeat Copine PF07002.11 CAR26878.1 - 0.012 15.3 0.0 0.064 13.0 0.0 2.2 2 0 0 2 2 2 0 Copine TPR_10 PF13374.1 CAR26878.1 - 0.026 14.4 19.4 3.2 7.8 0.0 8.8 11 0 0 11 11 9 0 Tetratricopeptide repeat Sld5 PF05916.6 CAR26879.1 - 1.3e-11 44.7 0.0 1.7e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein PEX11 PF05648.9 CAR26880.1 - 2.3e-53 180.7 4.0 2.6e-53 180.6 2.8 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Spt20 PF12090.3 CAR26881.1 - 8.1e-54 181.7 3.9 8.1e-54 181.7 2.7 3.7 2 2 1 3 3 3 1 Spt20 family DCP1 PF06058.8 CAR26882.1 - 6.9e-19 68.0 0.7 1.6e-09 37.8 0.0 3.1 1 1 2 3 3 3 3 Dcp1-like decapping family Ank_3 PF13606.1 CAR26882.1 - 0.043 14.0 0.0 0.27 11.5 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat GFO_IDH_MocA PF01408.17 CAR26883.1 - 6e-21 75.1 0.0 1e-20 74.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 CAR26883.1 - 7.9e-07 28.8 0.0 1.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain F420_oxidored PF03807.12 CAR26883.1 - 0.063 13.7 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrmB PF01978.14 CAR26883.1 - 0.12 12.0 0.0 0.41 10.3 0.0 1.8 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Hydantoinase_B PF02538.9 CAR26884.1 - 1.4e-217 723.0 0.1 2.5e-217 722.2 0.0 1.3 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 CAR26884.1 - 5.6e-88 294.7 0.0 1.4e-87 293.5 0.0 1.7 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 CAR26884.1 - 1.1e-54 184.6 0.3 1.4e-52 177.7 0.0 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region HMG_box PF00505.14 CAR26885.1 - 3.1e-11 43.3 3.0 3.1e-11 43.3 2.1 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CAR26885.1 - 1.8e-08 34.6 2.6 1.8e-08 34.6 1.8 2.2 2 1 0 2 2 2 1 HMG-box domain Mit_KHE1 PF10173.4 CAR26885.1 - 2.2 8.0 6.1 4.3 7.1 4.3 1.6 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related MRP-S28 PF10213.4 CAR26886.1 - 2.1e-50 170.0 2.7 4.7e-50 168.9 1.9 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Ada3 PF10198.4 CAR26887.1 - 7.6e-48 161.5 0.6 1.9e-47 160.2 0.4 1.7 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 UQ_con PF00179.21 CAR26888.1 - 6e-43 145.6 0.0 7.5e-43 145.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 CAR26888.1 - 3.9e-27 93.6 0.3 7e-27 92.7 0.2 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 CAR26888.1 - 0.00049 19.8 0.0 0.00076 19.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B Peptidase_M16 PF00675.15 CAR26889.1 - 1.4e-50 170.9 0.0 3e-50 169.8 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CAR26889.1 - 1.9e-37 128.6 0.0 3.6e-37 127.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain CybS PF05328.7 CAR26890.1 - 1.9e-47 160.2 0.0 2.3e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 CybS PCI PF01399.22 CAR26891.1 - 0.03 14.6 0.1 0.035 14.4 0.1 1.2 1 0 0 1 1 1 0 PCI domain PXA PF02194.10 CAR26892.1 - 4e-07 29.7 0.7 3.1e-05 23.6 0.5 2.5 1 1 0 1 1 1 1 PXA domain PseudoU_synth_2 PF00849.17 CAR26893.1 - 3.9e-19 69.0 0.4 9.2e-18 64.6 0.3 2.2 1 1 0 1 1 1 1 RNA pseudouridylate synthase Nipped-B_C PF12830.2 CAR26894.1 - 9.9e-47 159.0 5.4 1.1e-46 158.8 0.4 3.1 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 CAR26894.1 - 1.9e-13 50.0 0.8 7.9e-13 48.0 0.6 2.2 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Phage_Treg PF04761.7 CAR26894.1 - 0.025 14.3 1.1 0.56 10.0 0.1 2.6 2 0 0 2 2 2 0 Lactococcus bacteriophage putative transcription regulator SAS4 PF15460.1 CAR26895.1 - 5.9e-28 96.7 8.3 5.9e-28 96.7 5.8 2.0 2 0 0 2 2 2 1 Something about silencing, SAS, complex subunit 4 PAXIP1_C PF15364.1 CAR26895.1 - 0.021 14.7 5.3 0.12 12.3 0.6 2.5 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein Metallophos PF00149.23 CAR26896.1 - 1.2e-16 60.7 1.8 1.8e-16 60.1 1.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Sec10 PF07393.6 CAR26897.1 - 1.2e-198 661.7 19.3 1.6e-198 661.2 13.4 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 Thioredoxin PF00085.15 CAR26898.1 - 9.6e-09 34.8 0.0 1.7e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 CAR26898.1 - 3.9e-07 29.0 0.4 5.1e-07 28.6 0.3 1.1 1 0 0 1 1 1 1 Phosducin DIM1 PF02966.11 CAR26898.1 - 0.14 11.6 0.6 1.1 8.7 0.0 2.1 2 0 0 2 2 2 0 Mitosis protein DIM1 ubiquitin PF00240.18 CAR26899.1 - 2.7e-34 116.3 0.9 2.7e-34 116.3 0.6 1.9 2 1 1 3 3 3 1 Ubiquitin family Ribosomal_S27 PF01599.14 CAR26899.1 - 2.3e-23 81.7 2.2 4.3e-23 80.8 1.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 CAR26899.1 - 6.8e-20 70.5 3.0 1e-19 69.9 0.5 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CAR26899.1 - 1.2e-05 25.4 0.7 3.9e-05 23.8 0.1 2.1 2 1 0 2 2 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CAR26899.1 - 0.00011 21.8 0.0 0.00017 21.3 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CAR26899.1 - 0.0012 18.7 0.5 0.0026 17.6 0.4 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CAR26899.1 - 0.0034 17.5 0.2 0.0044 17.1 0.2 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain GCC2_GCC3 PF07699.8 CAR26899.1 - 0.015 14.8 1.6 0.025 14.1 1.1 1.4 1 0 0 1 1 1 0 GCC2 and GCC3 DZR PF12773.2 CAR26899.1 - 0.019 14.7 0.7 0.03 14.1 0.5 1.3 1 0 0 1 1 1 0 Double zinc ribbon DUF2870 PF11069.3 CAR26899.1 - 0.059 13.4 0.3 0.13 12.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) HypA PF01155.14 CAR26899.1 - 0.12 12.0 0.3 0.26 11.0 0.2 1.6 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Plexin_cytopl PF08337.7 CAR26899.1 - 0.13 10.5 2.0 3.9 5.6 0.1 2.0 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain DNA_RNApol_7kD PF03604.8 CAR26899.1 - 0.23 10.9 5.8 0.54 9.7 0.8 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit A2L_zn_ribbon PF08792.5 CAR26899.1 - 0.29 10.6 3.8 0.85 9.1 2.6 1.7 1 1 0 1 1 1 0 A2L zinc ribbon domain Nudix_N_2 PF14803.1 CAR26899.1 - 1.7 8.4 4.8 17 5.2 2.7 2.4 1 1 1 2 2 2 0 Nudix N-terminal ADK_lid PF05191.9 CAR26899.1 - 4 7.1 6.6 12 5.6 0.4 2.5 2 0 0 2 2 2 0 Adenylate kinase, active site lid Zn_ribbon_recom PF13408.1 CAR26899.1 - 9.5 6.5 9.7 37 4.6 3.3 2.9 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain HALZ PF02183.13 CAR26900.1 - 0.028 14.1 1.4 0.31 10.7 0.0 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper PRELI PF04707.9 CAR26901.1 - 5.2e-56 188.5 0.5 6.1e-56 188.3 0.3 1.1 1 0 0 1 1 1 1 PRELI-like family zf-DHHC PF01529.15 CAR26902.1 - 3.1e-36 124.3 5.6 3.1e-36 124.3 3.9 1.8 1 1 1 2 2 2 1 DHHC palmitoyltransferase MASE1 PF05231.9 CAR26902.1 - 0.19 10.7 5.2 0.048 12.6 0.3 2.0 2 0 0 2 2 2 0 MASE1 DUF4131 PF13567.1 CAR26902.1 - 0.99 8.7 6.4 0.52 9.6 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF35_N PF12172.3 CAR26902.1 - 1.7 8.6 6.6 0.2 11.5 1.1 2.1 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Packaging_FI PF14000.1 CAR26903.1 - 0.032 14.4 3.3 0.096 12.8 2.3 1.8 1 0 0 1 1 1 0 DNA packaging protein FI Nucleoplasmin PF03066.10 CAR26903.1 - 0.13 11.7 8.3 0.19 11.2 4.3 2.1 2 0 0 2 2 2 0 Nucleoplasmin Mito_fiss_reg PF05308.6 CAR26903.1 - 0.89 8.8 8.8 1.2 8.4 4.8 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator TFIIA PF03153.8 CAR26903.1 - 1.1 9.0 14.0 0.35 10.7 3.8 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2457 PF10446.4 CAR26903.1 - 1.5 7.4 17.4 0.1 11.3 8.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) TRAP_alpha PF03896.11 CAR26903.1 - 2.2 7.2 8.5 3.5 6.5 4.8 1.9 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit dCMP_cyt_deam_1 PF00383.17 CAR26904.1 - 2.6e-17 62.3 0.2 3.1e-17 62.0 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 CAR26904.1 - 3.3e-09 36.8 0.3 1.3e-08 34.8 0.0 1.8 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 CAR26904.1 - 0.00055 19.3 0.4 0.45 9.8 0.1 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Peptidase_M24 PF00557.19 CAR26905.1 - 1.4e-47 162.0 0.1 1.7e-47 161.7 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 ATP-cone PF03477.11 CAR26905.1 - 0.01 16.2 0.0 7.5 7.0 0.0 2.3 2 0 0 2 2 2 0 ATP cone domain Cpn60_TCP1 PF00118.19 CAR26906.1 - 3.2e-141 471.2 0.9 3.7e-141 471.0 0.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sec1 PF00995.18 CAR26907.1 - 2e-145 485.6 1.1 2.3e-145 485.4 0.8 1.0 1 0 0 1 1 1 1 Sec1 family TIP49 PF06068.8 CAR26908.1 - 1.6e-187 623.1 0.5 1.8e-187 622.9 0.3 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 CAR26908.1 - 1.4e-08 34.9 0.7 5.9e-05 23.2 0.0 2.8 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CAR26908.1 - 1.9e-08 33.6 1.9 2.8e-05 23.3 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 CAR26908.1 - 0.00071 19.5 0.2 0.002 18.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CAR26908.1 - 0.00074 19.5 0.1 0.25 11.2 0.0 2.5 3 0 0 3 3 3 2 AAA ATPase domain AAA_19 PF13245.1 CAR26908.1 - 0.002 17.8 0.1 0.015 15.0 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 CAR26908.1 - 0.011 14.7 0.1 0.027 13.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DnaB_C PF03796.10 CAR26908.1 - 0.028 13.3 0.0 0.05 12.4 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Mg_chelatase PF01078.16 CAR26908.1 - 0.03 13.4 0.1 4.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI CPT PF07931.7 CAR26908.1 - 0.043 13.4 0.0 0.087 12.4 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_5 PF07728.9 CAR26908.1 - 0.048 13.3 0.1 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CAR26908.1 - 0.099 12.0 0.0 0.24 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain SIR2 PF02146.12 CAR26909.1 - 1.8e-28 99.4 0.1 3.4e-28 98.5 0.1 1.4 1 1 0 1 1 1 1 Sir2 family ATP_bind_1 PF03029.12 CAR26910.1 - 1.2e-85 286.8 0.0 1.3e-85 286.7 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 CAR26910.1 - 0.0001 23.1 0.1 0.00027 21.7 0.0 1.9 1 1 1 2 2 1 1 AAA domain AAA_10 PF12846.2 CAR26910.1 - 0.00018 21.0 0.0 0.00042 19.8 0.0 1.5 2 0 0 2 2 2 1 AAA-like domain ArgK PF03308.11 CAR26910.1 - 0.00066 18.5 0.0 0.0011 17.8 0.0 1.2 1 0 0 1 1 1 1 ArgK protein MMR_HSR1 PF01926.18 CAR26910.1 - 0.0011 18.8 0.0 0.0026 17.7 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CAR26910.1 - 0.0053 16.8 0.0 0.033 14.3 0.0 2.2 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.17 CAR26910.1 - 0.0073 16.4 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 RNA helicase MobB PF03205.9 CAR26910.1 - 0.0084 15.8 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 CAR26910.1 - 0.0094 16.2 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 CAR26910.1 - 0.0096 14.9 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain AAA_33 PF13671.1 CAR26910.1 - 0.017 14.9 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 CAR26910.1 - 0.021 14.4 0.0 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 CAR26910.1 - 0.021 15.1 0.0 0.041 14.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.22 CAR26910.1 - 0.027 13.9 0.0 0.59 9.5 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.1 CAR26910.1 - 0.05 13.1 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 CAR26910.1 - 0.056 12.6 0.0 0.099 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 cobW PF02492.14 CAR26910.1 - 0.067 12.6 0.0 0.85 9.0 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 CAR26910.1 - 0.075 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.1 CAR26910.1 - 0.078 12.8 0.0 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 CAR26910.1 - 0.081 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.7 CAR26910.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin DUF87 PF01935.12 CAR26910.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 Septin PF00735.13 CAR26910.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_19 PF13245.1 CAR26910.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 CAR26910.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA PF00004.24 CAR26910.1 - 0.15 12.2 0.0 0.39 10.9 0.0 1.7 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CAR26910.1 - 0.15 12.0 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 CAR26910.1 - 0.15 11.5 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 CAR26910.1 - 0.16 12.4 0.0 3.4 8.1 0.0 2.7 2 1 1 3 3 3 0 Miro-like protein zf-CCCH PF00642.19 CAR26911.1 - 2e-06 27.3 4.6 2e-06 27.3 3.2 1.8 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nucleoporin_FG PF13634.1 CAR26911.1 - 2.8 8.2 184.8 2.9 8.1 39.2 5.2 1 1 3 4 4 4 0 Nucleoporin FG repeat region Arv1 PF04161.8 CAR26912.1 - 1e-74 250.9 12.4 1.4e-74 250.4 8.6 1.2 1 0 0 1 1 1 1 Arv1-like family DUF221 PF02714.10 CAR26913.1 - 5.6e-102 340.9 19.7 5.6e-102 340.9 13.6 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CAR26913.1 - 8.3e-40 135.9 3.9 8.3e-40 135.9 2.7 2.3 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 CAR26913.1 - 3e-15 56.4 0.0 7.2e-15 55.2 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4463) PI3Ka PF00613.15 CAR26914.1 - 9.6e-70 233.5 2.1 1.5e-69 232.8 1.5 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 CAR26914.1 - 7.2e-47 159.8 0.0 2.6e-45 154.7 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 CAR26914.1 - 1.3e-20 73.6 0.3 3.1e-20 72.3 0.2 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DEAD PF00270.24 CAR26915.1 - 5.1e-39 133.4 0.5 5.1e-39 133.4 0.3 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR26915.1 - 6.1e-20 70.8 0.1 1.3e-19 69.8 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAR26915.1 - 2.4e-05 24.2 0.1 4.9e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 CAR26915.1 - 0.0084 15.1 0.1 0.015 14.2 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 CAR26915.1 - 0.014 14.9 0.0 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain CoaE PF01121.15 CAR26917.1 - 2.4e-58 196.5 0.0 3.2e-58 196.1 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 CAR26917.1 - 5.7e-08 33.6 0.0 8.7e-08 33.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CAR26917.1 - 0.00015 22.0 0.1 0.00073 19.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CAR26917.1 - 0.00022 21.1 0.0 0.00046 20.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CAR26917.1 - 0.0023 17.8 0.0 0.0043 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 CAR26917.1 - 0.018 14.9 0.0 0.084 12.7 0.0 1.9 2 0 0 2 2 2 0 Cytidylate kinase-like family SKI PF01202.17 CAR26917.1 - 0.034 14.0 0.0 0.096 12.5 0.0 1.7 2 0 0 2 2 2 0 Shikimate kinase Spore_IV_A PF09547.5 CAR26917.1 - 0.063 11.9 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) ApbA_C PF08546.6 CAR26918.1 - 4.4e-13 49.3 0.0 2.3e-12 47.0 0.0 2.2 2 1 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal SET PF00856.23 CAR26919.1 - 0.041 14.1 0.2 0.11 12.8 0.1 1.7 1 1 0 1 1 1 0 SET domain BPL_LplA_LipB PF03099.14 CAR26920.1 - 2.6e-16 59.7 0.0 4.9e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Recep_L_domain PF01030.19 CAR26920.1 - 0.11 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Receptor L domain FHA PF00498.21 CAR26921.1 - 1.9e-19 69.5 0.3 4e-18 65.2 0.2 2.8 2 0 0 2 2 2 1 FHA domain DUF2205 PF10224.4 CAR26921.1 - 0.2 11.2 21.5 0.72 9.4 0.1 3.7 1 1 2 3 3 3 0 Predicted coiled-coil protein (DUF2205) YjgP_YjgQ PF03739.9 CAR26921.1 - 0.69 8.5 3.0 1.6 7.3 2.0 1.6 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family DASH_Spc19 PF08287.6 CAR26922.1 - 9.6e-36 122.7 12.8 1.1e-35 122.5 8.9 1.0 1 0 0 1 1 1 1 Spc19 DUF465 PF04325.8 CAR26922.1 - 0.031 13.9 1.5 0.049 13.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF465) bZIP_2 PF07716.10 CAR26922.1 - 0.46 10.3 13.2 0.56 10.0 0.1 3.4 3 0 0 3 3 3 0 Basic region leucine zipper RICH PF05062.7 CAR26922.1 - 2.3 8.4 7.2 29 4.8 5.0 2.3 1 1 0 1 1 1 0 RICH domain DASH_Dad2 PF08654.5 CAR26922.1 - 6.5 6.8 9.4 4.5 7.3 1.2 3.1 2 1 1 3 3 3 0 DASH complex subunit Dad2 Rogdi_lz PF10259.4 CAR26923.1 - 3e-78 262.6 3.2 3.3e-78 262.5 2.3 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Coq4 PF05019.8 CAR26924.1 - 1.9e-95 317.9 0.0 2.4e-95 317.6 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Transp_cyt_pur PF02133.10 CAR26925.1 - 1.3e-70 238.1 33.5 1.3e-70 238.1 23.2 1.3 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Cation_efflux PF01545.16 CAR26926.1 - 2.3e-56 190.9 5.2 2.3e-56 190.9 3.6 2.2 2 0 0 2 2 2 1 Cation efflux family DUF2946 PF11162.3 CAR26926.1 - 0.0056 16.8 12.0 2.1 8.6 2.3 3.9 3 0 0 3 3 3 2 Protein of unknown function (DUF2946) CKAP2_C PF15297.1 CAR26926.1 - 0.014 14.2 8.1 0.36 9.5 0.0 2.1 2 0 0 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus 60KD_IMP PF02096.15 CAR26926.1 - 0.017 14.8 0.7 0.051 13.2 0.5 1.9 1 0 0 1 1 1 0 60Kd inner membrane protein RXT2_N PF08595.6 CAR26926.1 - 0.018 14.8 0.2 0.018 14.8 0.1 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal Ctr PF04145.10 CAR26926.1 - 0.04 13.9 4.6 0.28 11.2 0.2 3.1 3 0 0 3 3 3 0 Ctr copper transporter family FAM176 PF14851.1 CAR26926.1 - 0.044 13.4 0.5 0.044 13.4 0.3 2.4 2 0 0 2 2 2 0 FAM176 family SelP_N PF04592.9 CAR26926.1 - 0.051 12.9 25.3 0.78 9.0 0.1 3.1 3 0 0 3 3 3 0 Selenoprotein P, N terminal region DUF3154 PF11351.3 CAR26926.1 - 0.06 13.1 0.1 0.23 11.2 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3154) Suf PF05843.9 CAR26926.1 - 0.19 11.4 3.6 0.41 10.3 2.5 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ycf1 PF05758.7 CAR26926.1 - 0.21 9.2 2.5 0.34 8.5 1.7 1.2 1 0 0 1 1 1 0 Ycf1 Pex14_N PF04695.8 CAR26926.1 - 0.36 10.8 11.7 0.39 10.7 2.3 3.1 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region EphA2_TM PF14575.1 CAR26926.1 - 4.2 7.8 5.5 1.7 9.0 0.1 3.1 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Topoisom_bac PF01131.15 CAR26927.1 - 1.3e-94 317.2 0.0 1.9e-94 316.7 0.0 1.2 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 CAR26927.1 - 5.3e-20 71.2 0.0 1.1e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 Toprim domain EST1_DNA_bind PF10373.4 CAR26928.1 - 2.2e-53 181.2 0.2 2.2e-53 181.2 0.1 2.0 3 0 0 3 3 3 1 Est1 DNA/RNA binding domain EST1 PF10374.4 CAR26928.1 - 2.6e-20 72.7 1.4 5.7e-20 71.6 0.2 2.2 2 0 0 2 2 2 1 Telomerase activating protein Est1 Hydrolase_3 PF08282.7 CAR26928.1 - 0.069 12.7 0.2 0.18 11.3 0.2 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase TPR_11 PF13414.1 CAR26928.1 - 0.096 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 TPR repeat Zn_clus PF00172.13 CAR26929.1 - 1.6e-08 34.3 7.6 2.7e-08 33.5 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nucleoplasmin PF03066.10 CAR26929.1 - 2 7.9 14.0 0.11 12.0 1.9 2.8 2 0 0 2 2 2 0 Nucleoplasmin Aminotran_5 PF00266.14 CAR26930.1 - 3.2e-14 52.4 0.0 3.5e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CAR26930.1 - 0.056 12.5 0.0 0.19 10.8 0.0 1.8 2 0 0 2 2 2 0 Beta-eliminating lyase Stork_head PF10264.4 CAR26930.1 - 0.14 12.3 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain PIP5K PF01504.13 CAR26931.1 - 4.6e-83 278.1 0.6 4.6e-83 278.1 0.4 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Rep_4 PF05797.6 CAR26932.1 - 1.2e-147 491.0 0.0 1.4e-147 490.8 0.0 1.0 1 0 0 1 1 1 1 Yeast trans-acting factor (REP1/REP2) CYSTM PF12734.2 CAR26933.1 - 3.4e-06 27.0 46.4 0.038 14.0 31.1 3.4 1 1 0 1 1 1 1 Cysteine-rich TM module stress tolerance CPSase_L_D2 PF02786.12 CAR26934.1 - 2e-81 272.2 0.2 3.3e-81 271.6 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 CAR26934.1 - 1.1e-64 217.5 0.0 1.7e-64 216.8 0.0 1.3 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 CAR26934.1 - 9e-36 122.3 0.0 2.1e-35 121.1 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CAR26934.1 - 2.6e-32 110.9 0.0 5.5e-31 106.7 0.0 2.4 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 CAR26934.1 - 8.6e-28 97.5 0.0 1.7e-27 96.6 0.0 1.5 1 0 0 1 1 1 1 HMGL-like ATPgrasp_Ter PF15632.1 CAR26934.1 - 1.1e-18 67.0 0.0 6.2e-18 64.6 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 CAR26934.1 - 1.1e-18 66.5 3.2 1.1e-18 66.5 2.2 2.4 3 0 0 3 3 3 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 CAR26934.1 - 1.9e-14 53.8 0.1 3.3e-14 53.0 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CAR26934.1 - 7.6e-06 25.4 0.0 1.7e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 CAR26934.1 - 1.1e-05 24.9 2.6 0.023 14.3 0.1 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.17 CAR26934.1 - 2.1e-05 23.9 0.0 4.5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 CAR26934.1 - 7e-05 22.7 0.0 0.00018 21.4 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 CAR26934.1 - 0.00052 19.5 0.0 0.0086 15.5 0.0 2.2 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD PF00529.15 CAR26934.1 - 0.00089 18.6 1.3 0.25 10.5 0.0 2.3 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_3 PF13437.1 CAR26934.1 - 0.0013 19.0 1.9 0.3 11.4 0.0 3.3 3 0 0 3 3 3 1 HlyD family secretion protein HlyD_2 PF12700.2 CAR26934.1 - 0.029 13.5 0.4 4.4 6.3 0.0 2.2 1 1 1 2 2 2 0 HlyD family secretion protein RnfC_N PF13375.1 CAR26934.1 - 0.057 13.1 1.9 2.6 7.7 0.4 3.1 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain DASH_Duo1 PF08651.5 CAR26935.1 - 7e-25 86.4 0.4 1.9e-24 84.9 0.3 1.8 1 0 0 1 1 1 1 DASH complex subunit Duo1 Tweety PF04906.8 CAR26935.1 - 0.086 11.2 0.6 0.1 10.9 0.4 1.2 1 0 0 1 1 1 0 Tweety DUF755 PF05501.6 CAR26935.1 - 0.1 12.6 7.2 0.13 12.3 2.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF755) APG12 PF04110.8 CAR26936.1 - 6.8e-27 93.4 0.6 1.4e-26 92.4 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin-like autophagy protein Apg12 Pox_RNA_Pol_19 PF05320.7 CAR26936.1 - 6.2 6.5 7.3 0.93 9.2 1.3 1.9 1 1 1 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Kinetochor_Ybp2 PF08568.5 CAR26937.1 - 6.6e-152 506.9 16.1 7.4e-152 506.8 11.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin LRR_4 PF12799.2 CAR26937.1 - 0.13 11.9 6.2 0.36 10.5 0.3 3.4 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) HUN PF08729.5 CAR26938.1 - 3.1e-14 52.5 0.0 1e-13 50.8 0.0 2.0 1 0 0 1 1 1 1 HPC2 and ubinuclein domain BCDHK_Adom3 PF10436.4 CAR26939.1 - 4.8e-36 123.7 0.3 9.8e-36 122.7 0.2 1.5 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CAR26939.1 - 2.9e-10 39.8 0.0 1.9e-09 37.2 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UQ_con PF00179.21 CAR26940.1 - 1.8e-50 169.9 0.1 2.1e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CAR26940.1 - 5.6e-06 26.1 0.0 8.5e-06 25.5 0.0 1.3 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CAR26940.1 - 0.02 14.7 0.3 0.063 13.1 0.2 1.8 1 1 0 1 1 1 0 RWD domain UEV PF05743.8 CAR26940.1 - 0.03 14.0 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 UEV domain Nucleoplasmin PF03066.10 CAR26940.1 - 7.4 6.0 8.0 9.8 5.6 5.5 1.2 1 0 0 1 1 1 0 Nucleoplasmin Rabaptin PF03528.10 CAR26941.1 - 0.031 14.2 1.8 0.06 13.2 1.2 1.5 1 0 0 1 1 1 0 Rabaptin CBS PF00571.23 CAR26942.1 - 2.1e-23 81.8 0.2 1.8e-05 24.4 0.0 5.3 5 0 0 5 5 5 5 CBS domain Macoilin PF09726.4 CAR26942.1 - 0.19 9.9 5.6 0.21 9.8 3.9 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF4175 PF13779.1 CAR26942.1 - 0.35 8.5 16.5 0.54 7.8 11.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) FA_desaturase PF00487.19 CAR26943.1 - 5.9e-19 68.5 17.0 5.9e-19 68.5 11.8 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 CAR26943.1 - 5.9e-14 51.6 0.0 1.3e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3466 PF11949.3 CAR26943.1 - 0.094 11.2 0.0 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3466) Sirohm_synth_C PF14823.1 CAR26944.1 - 5.5e-26 89.6 0.1 9.7e-26 88.8 0.1 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal NAD_binding_7 PF13241.1 CAR26944.1 - 1.7e-23 82.8 0.0 2.5e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.1 CAR26944.1 - 1e-14 53.1 0.0 1.8e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Shikimate_DH PF01488.15 CAR26944.1 - 0.0024 17.9 0.0 0.0053 16.8 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 CAR26944.1 - 0.027 13.6 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 CAR26944.1 - 0.13 12.3 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RRM_1 PF00076.17 CAR26945.1 - 3.3e-41 138.7 0.0 2.5e-17 62.2 0.0 4.3 6 0 0 6 6 6 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR26945.1 - 3.9e-28 97.2 0.0 4e-12 45.9 0.0 3.8 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR26945.1 - 9.3e-22 76.6 0.0 9.8e-10 38.1 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CAR26945.1 - 0.00043 19.9 0.0 0.00089 18.9 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 CAR26945.1 - 0.012 15.4 0.0 0.012 15.4 0.0 2.9 4 0 0 4 4 4 0 RNA binding motif DUF4407 PF14362.1 CAR26945.1 - 0.21 10.5 13.5 0.43 9.4 9.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6 PF04111.7 CAR26946.1 - 0.21 10.5 7.4 0.3 10.1 5.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Cornichon PF03311.9 CAR26947.1 - 1.2e-51 174.1 12.6 1.4e-51 173.9 8.7 1.0 1 0 0 1 1 1 1 Cornichon protein Bac_export_2 PF01312.14 CAR26947.1 - 0.61 8.9 5.4 0.87 8.4 3.7 1.4 1 1 0 1 1 1 0 FlhB HrpN YscU SpaS Family TRAM_LAG1_CLN8 PF03798.11 CAR26947.1 - 2.5 7.6 10.2 8.1 5.9 2.7 2.5 2 1 0 2 2 2 0 TLC domain WSC PF01822.14 CAR26948.1 - 8.6e-05 22.3 6.7 0.00023 21.0 4.7 1.7 1 0 0 1 1 1 1 WSC domain DUF1191 PF06697.7 CAR26948.1 - 0.00044 19.1 0.0 0.00068 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Mid2 PF04478.7 CAR26948.1 - 0.013 14.8 1.9 0.037 13.4 1.1 1.9 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor DUF2762 PF10960.3 CAR26948.1 - 0.073 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) DUF2408 PF10303.4 CAR26949.1 - 2.3e-76 254.3 18.3 3.6e-49 166.3 1.0 5.2 3 2 2 5 5 5 5 Protein of unknown function (DUF2408) Laminin_II PF06009.7 CAR26949.1 - 4.7 6.9 12.0 5.2 6.8 0.5 3.8 4 0 0 4 4 4 0 Laminin Domain II AATF-Che1 PF13339.1 CAR26949.1 - 7.4 6.7 25.6 0.17 12.0 1.9 5.6 3 2 2 5 5 5 0 Apoptosis antagonizing transcription factor AhpC-TSA PF00578.16 CAR26950.1 - 1.2e-27 96.0 0.0 1.6e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CAR26950.1 - 1.1e-18 67.1 0.0 1.7e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 CAR26950.1 - 0.0053 16.6 0.0 0.008 16.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Daxx PF03344.10 CAR26950.1 - 0.056 11.9 35.4 0.018 13.5 13.4 2.1 2 0 0 2 2 2 0 Daxx Family Nop14 PF04147.7 CAR26950.1 - 9.1 4.0 37.3 2.9 5.6 3.7 2.1 2 0 0 2 2 2 0 Nop14-like family Adap_comp_sub PF00928.16 CAR26951.1 - 1.7e-85 286.3 0.8 2.2e-85 285.9 0.5 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CAR26951.1 - 7.4e-07 28.9 1.2 1.5e-06 27.9 0.6 1.7 1 1 0 1 1 1 1 Clathrin adaptor complex small chain TPP1 PF10341.4 CAR26952.1 - 5.2e-05 23.1 0.0 6.4e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD HMGL-like PF00682.14 CAR26953.1 - 5.9e-67 225.7 0.0 1.1e-66 224.8 0.0 1.4 2 0 0 2 2 2 1 HMGL-like LeuA_dimer PF08502.5 CAR26953.1 - 1.8e-20 73.0 0.0 3.6e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Urm1 PF09138.6 CAR26954.1 - 7e-35 119.0 0.4 7.8e-35 118.8 0.2 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 CAR26954.1 - 0.00053 20.3 0.0 0.00066 20.0 0.0 1.2 1 0 0 1 1 1 1 ThiS family Cupin_2 PF07883.6 CAR26954.1 - 0.084 12.3 0.0 0.24 10.9 0.0 1.8 2 0 0 2 2 2 0 Cupin domain GRASP55_65 PF04495.9 CAR26955.1 - 2.9e-05 24.0 0.0 5.8e-05 23.0 0.0 1.5 2 0 0 2 2 2 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 CAR26955.1 - 5.3e-05 23.0 0.0 0.00013 21.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 CAR26955.1 - 0.0047 17.0 0.1 0.051 13.7 0.0 2.2 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) DUF883 PF05957.8 CAR26955.1 - 0.1 13.0 1.3 1.9 8.9 0.2 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Cnl2_NKP2 PF09447.5 CAR26955.1 - 0.11 12.1 0.4 0.88 9.2 0.0 2.1 2 0 0 2 2 2 0 Cnl2/NKP2 family protein Apolipoprotein PF01442.13 CAR26955.1 - 0.41 10.1 3.1 1.8 7.9 2.2 1.9 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Porin_3 PF01459.17 CAR26956.1 - 8.2e-81 271.2 0.1 9.5e-81 271.0 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin Acetyltransf_13 PF13880.1 CAR26956.1 - 0.15 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase DUF2373 PF10180.4 CAR26956.1 - 0.16 11.5 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Med9 PF07544.8 CAR26957.1 - 2.5e-26 91.2 0.3 3.2e-26 90.8 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 NBP1 PF08537.5 CAR26957.1 - 0.062 12.4 2.5 0.067 12.3 1.5 1.2 1 1 0 1 1 1 0 Fungal Nap binding protein NBP1 DUF4200 PF13863.1 CAR26957.1 - 0.098 12.6 3.5 0.13 12.1 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) ERG2_Sigma1R PF04622.7 CAR26958.1 - 2.1e-88 295.1 0.3 2.6e-88 294.8 0.2 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Whi5 PF08528.6 CAR26959.1 - 1.6e-11 43.4 1.4 3.1e-11 42.5 1.0 1.5 1 0 0 1 1 1 1 Whi5 like PID_2 PF14719.1 CAR26959.1 - 0.0012 18.5 1.3 0.0031 17.1 0.8 1.7 1 1 1 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) DUF3439 PF11921.3 CAR26959.1 - 0.21 11.3 4.2 0.36 10.5 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) LCAT PF02450.10 CAR26960.1 - 1e-131 439.5 0.1 1.3e-131 439.1 0.1 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 CAR26960.1 - 0.0011 18.7 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.13 CAR26960.1 - 0.003 16.8 0.1 0.0073 15.6 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 2) Abhydrolase_6 PF12697.2 CAR26960.1 - 0.0035 17.2 0.0 0.0081 16.0 0.0 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAR26960.1 - 0.0035 16.9 0.0 0.0094 15.5 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1749 PF08538.5 CAR26960.1 - 0.0057 15.5 0.0 0.0096 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) DUF900 PF05990.7 CAR26960.1 - 0.071 12.4 0.0 0.22 10.8 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Autophagy_N PF03986.8 CAR26961.1 - 5.2e-41 139.8 0.7 5.2e-41 139.8 0.5 2.1 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 CAR26961.1 - 8.9e-22 77.0 1.9 1.9e-21 76.0 0.4 2.3 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 CAR26961.1 - 1.8e-14 52.5 2.1 3.3e-14 51.6 1.5 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal RRP7 PF12923.2 CAR26961.1 - 0.28 11.2 5.1 0.45 10.5 0.5 2.1 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) RXT2_N PF08595.6 CAR26961.1 - 0.69 9.7 5.1 0.24 11.1 0.2 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.5 CAR26961.1 - 1.2 9.4 5.7 7.9 6.7 0.5 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain XPA_C PF05181.7 CAR26962.1 - 2.7e-24 84.5 1.6 1.5e-23 82.1 0.2 2.5 2 0 0 2 2 2 1 XPA protein C-terminus DUF3027 PF11228.3 CAR26962.1 - 0.065 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3027) XPA_N PF01286.13 CAR26962.1 - 1.4 8.6 5.3 0.21 11.3 0.6 1.9 2 0 0 2 2 2 0 XPA protein N-terminal SAPS PF04499.10 CAR26962.1 - 1.6 7.2 8.8 0.048 12.2 2.1 1.4 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein VHS PF00790.14 CAR26963.1 - 5.5e-37 126.5 0.4 4.9e-36 123.4 0.0 2.2 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 CAR26963.1 - 7.8e-19 67.3 2.8 7.8e-19 67.3 2.0 2.0 2 0 0 2 2 2 1 FYVE zinc finger UIM PF02809.15 CAR26963.1 - 0.0072 15.8 0.7 0.0072 15.8 0.5 4.1 5 0 0 5 5 5 2 Ubiquitin interaction motif zf-AN1 PF01428.11 CAR26963.1 - 5.5 6.9 14.1 0.23 11.3 5.4 2.0 2 0 0 2 2 2 0 AN1-like Zinc finger Rot1 PF10681.4 CAR26964.1 - 9.6e-94 312.6 0.0 1.1e-93 312.4 0.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Cyclin_N PF00134.18 CAR26965.1 - 1.2e-38 131.5 0.0 3.2e-38 130.1 0.0 1.8 1 0 0 1 1 1 1 Cyclin, N-terminal domain BBP1_C PF15272.1 CAR26967.1 - 1.1e-63 214.4 25.2 1.1e-63 214.4 17.5 1.5 2 0 0 2 2 2 1 Spindle pole body component BBP1, C-terminal BBP1_N PF15271.1 CAR26967.1 - 1.4e-51 174.6 0.5 1.4e-51 174.6 0.3 2.5 2 1 0 2 2 2 1 Spindle pole body component BBP1, Mps2-binding protein DUF4515 PF14988.1 CAR26967.1 - 0.0065 16.1 22.0 0.1 12.2 4.0 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4515) zf-DBF PF07535.7 CAR26967.1 - 0.073 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 DBF zinc finger Pox_A_type_inc PF04508.7 CAR26967.1 - 3 7.8 9.3 24 5.0 0.1 4.3 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat PhoU PF01895.14 CAR26967.1 - 4 7.9 8.5 2.7 8.4 2.6 2.8 1 1 1 2 2 2 0 PhoU domain SAGA-Tad1 PF12767.2 CAR26968.1 - 3.3e-73 246.4 1.5 4.5e-72 242.7 0.0 2.1 1 1 1 2 2 2 2 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.9 CAR26968.1 - 0.0045 16.2 0.0 0.0069 15.6 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family TFIID_30kDa PF03540.8 CAR26968.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit Vps51 PF08700.6 CAR26969.1 - 5.1 7.0 24.2 4.2 7.2 1.4 5.5 5 1 0 5 5 5 0 Vps51/Vps67 Baculo_PEP_C PF04513.7 CAR26969.1 - 8.1 6.2 7.1 4.5 7.0 0.6 2.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fer2 PF00111.22 CAR26970.1 - 1.7e-14 53.3 0.4 2.3e-14 52.8 0.2 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain V-SNARE PF05008.10 CAR26971.1 - 1.5e-20 73.1 7.1 1.7e-20 72.9 3.2 2.1 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 CAR26971.1 - 1.4e-19 69.9 2.3 1.4e-19 69.9 1.6 2.8 2 1 1 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 CAR26971.1 - 0.0025 17.4 0.2 0.0025 17.4 0.1 2.2 3 0 0 3 3 3 1 Sec20 Baculo_p24 PF05073.7 CAR26971.1 - 0.088 12.3 5.5 0.04 13.4 0.6 2.0 1 1 1 2 2 2 0 Baculovirus P24 capsid protein Snapin_Pallidin PF14712.1 CAR26971.1 - 0.28 11.4 8.3 0.22 11.8 2.5 2.7 1 1 2 3 3 3 0 Snapin/Pallidin Prominin PF05478.6 CAR26971.1 - 0.38 8.2 4.3 0.91 6.9 3.0 1.4 1 1 0 1 1 1 0 Prominin YqjK PF13997.1 CAR26971.1 - 0.45 10.7 0.0 0.45 10.7 0.0 2.3 3 0 0 3 3 3 0 YqjK-like protein Nsp1_C PF05064.8 CAR26971.1 - 0.74 9.4 6.3 0.15 11.7 1.3 2.1 2 1 1 3 3 3 0 Nsp1-like C-terminal region DUF883 PF05957.8 CAR26971.1 - 3.8 7.9 6.1 12 6.3 0.3 3.0 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Glyco_hydro_63 PF03200.11 CAR26972.1 - 1e-05 23.6 6.1 0.00046 18.1 0.2 3.6 3 1 0 3 3 3 2 Mannosyl oligosaccharide glucosidase DUF1903 PF08991.5 CAR26976.1 - 5.5e-25 87.3 7.8 6.6e-25 87.0 5.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) Cmc1 PF08583.5 CAR26976.1 - 0.24 11.1 8.3 0.17 11.7 1.1 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like PIP49_C PF12260.3 CAR26976.1 - 1.7 7.9 6.7 1.5 8.1 4.6 1.0 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 ORC4_C PF14629.1 CAR26977.1 - 0.026 13.8 0.5 0.034 13.5 0.4 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus Bul1_N PF04425.7 CAR26978.1 - 7.4e-91 304.8 2.0 1.8e-88 297.0 0.1 2.3 1 1 1 2 2 2 2 Bul1 N terminus Bul1_C PF04426.7 CAR26978.1 - 3.3e-25 88.8 0.2 1.5e-11 44.0 0.0 2.8 1 1 1 2 2 2 2 Bul1 C terminus Arrestin_N PF00339.24 CAR26978.1 - 0.023 14.4 0.2 0.15 11.8 0.0 2.5 2 1 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Bul1_N PF04425.7 CAR26979.1 - 2.2e-91 306.6 3.3 2.6e-89 299.8 0.2 2.0 1 1 1 2 2 2 2 Bul1 N terminus Bul1_C PF04426.7 CAR26979.1 - 3.7e-06 26.3 0.0 7.6e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Bul1 C terminus Arrestin_N PF00339.24 CAR26979.1 - 0.036 13.8 0.1 0.18 11.6 0.1 2.1 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain Ribosomal_L36e PF01158.13 CAR26980.1 - 4e-36 122.9 2.2 4.4e-36 122.7 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Ribosomal_L28 PF00830.14 CAR26981.1 - 6.8e-19 67.4 0.3 1.4e-18 66.4 0.2 1.5 1 0 0 1 1 1 1 Ribosomal L28 family CDP-OH_P_transf PF01066.16 CAR26982.1 - 1.1e-11 44.9 3.7 2.1e-11 43.9 2.6 1.4 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Peptidase_S10 PF00450.17 CAR26983.1 - 1.3e-98 330.8 0.1 1.9e-98 330.3 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase CDC45 PF02724.9 CAR26983.1 - 0.0016 16.5 6.6 0.0023 16.0 4.6 1.2 1 0 0 1 1 1 1 CDC45-like protein DUF912 PF06024.7 CAR26983.1 - 0.13 12.3 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) YL1 PF05764.8 CAR26983.1 - 0.22 11.0 10.2 0.38 10.3 7.1 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Aminotran_1_2 PF00155.16 CAR26984.1 - 4.4e-27 94.9 0.0 5.5e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CAR26984.1 - 0.023 13.8 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Phosphorylase PF00343.15 CAR26985.1 - 9.4e-302 1002.2 0.5 1.1e-301 1002.0 0.3 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase MCM PF00493.18 CAR26986.1 - 6.9e-136 452.4 0.2 9.9e-136 451.8 0.2 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CAR26986.1 - 1.6e-19 70.5 2.3 6e-19 68.7 0.0 2.7 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 CAR26986.1 - 3.7e-07 29.5 0.0 1.1e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CAR26986.1 - 0.0056 16.1 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain RRN3 PF05327.6 CAR26986.1 - 0.013 13.6 2.7 0.022 12.8 1.9 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 AAA_3 PF07726.6 CAR26986.1 - 0.017 14.7 0.0 0.047 13.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF3536 PF12055.3 CAR26986.1 - 0.029 13.5 0.5 0.88 8.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3536) AAA_5 PF07728.9 CAR26986.1 - 0.034 13.8 0.0 0.068 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Cyclin_N PF00134.18 CAR26987.1 - 6.9e-39 132.3 0.1 6.9e-39 132.3 0.1 3.0 3 0 0 3 3 3 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CAR26987.1 - 2.3e-32 111.3 1.4 2.1e-31 108.2 0.0 2.5 2 0 0 2 2 2 1 Cyclin, C-terminal domain BTV_NS2 PF04514.7 CAR26987.1 - 0.12 11.2 10.1 0.2 10.4 7.0 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 PH_4 PF15404.1 CAR26987.1 - 0.38 10.2 6.9 0.87 9.0 4.7 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Suf PF05843.9 CAR26987.1 - 1.8 8.2 11.2 3.2 7.4 7.8 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Zip PF02535.17 CAR26987.1 - 4.5 6.1 5.2 6.7 5.6 3.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Cyclin_N PF00134.18 CAR26988.1 - 2.7e-40 136.8 0.3 2.7e-40 136.8 0.2 2.6 3 0 0 3 3 3 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CAR26988.1 - 3.9e-19 68.7 0.1 1.5e-18 66.8 0.0 2.0 1 0 0 1 1 1 1 Cyclin, C-terminal domain QRPTase_C PF01729.14 CAR26990.1 - 0.047 13.1 0.0 0.071 12.6 0.0 1.2 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Abhydrolase_1 PF00561.15 CAR26991.1 - 7e-20 71.5 0.2 1.2e-19 70.8 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CAR26991.1 - 1.9e-18 67.2 0.0 3.3e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CAR26991.1 - 1.2e-05 25.0 0.0 2.7e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CAR26991.1 - 0.0052 16.0 0.1 0.66 9.1 0.0 3.0 3 0 0 3 3 3 1 Prolyl oligopeptidase family Ser_hydrolase PF06821.8 CAR26991.1 - 0.017 14.7 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase CCSMST1 PF15013.1 CAR26992.1 - 0.099 12.5 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 CCSMST1 family Peptidase_M16 PF00675.15 CAR26993.1 - 1.4e-32 112.5 0.1 5.8e-32 110.4 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CAR26993.1 - 8.7e-12 45.0 1.6 0.0002 21.0 0.0 5.1 5 0 0 5 5 5 2 Peptidase M16 inactive domain DUF3135 PF11333.3 CAR26993.1 - 0.0055 16.8 0.5 0.021 14.9 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3135) Acetyltransf_7 PF13508.1 CAR26994.1 - 3.5e-08 33.4 0.1 7.4e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CAR26994.1 - 0.00021 21.1 0.2 0.0013 18.6 0.1 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CAR26994.1 - 0.0032 17.4 0.1 0.0084 16.1 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CAR26994.1 - 0.023 14.8 0.0 0.061 13.4 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 CAR26994.1 - 0.025 14.5 0.0 0.069 13.0 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TLD PF07534.11 CAR26994.1 - 0.036 14.0 0.0 0.083 12.8 0.0 1.7 1 1 1 2 2 2 0 TLD Acetyltransf_CG PF14542.1 CAR26994.1 - 0.041 13.7 0.0 0.097 12.5 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase SURF1 PF02104.10 CAR26995.1 - 9.1e-65 218.4 0.7 1.2e-64 218.0 0.5 1.1 1 0 0 1 1 1 1 SURF1 family ig PF00047.20 CAR26995.1 - 0.021 14.9 0.0 0.1 12.7 0.0 2.2 2 0 0 2 2 2 0 Immunoglobulin domain DASH_Dam1 PF08653.5 CAR26996.1 - 5.9e-28 96.4 0.4 1e-27 95.6 0.3 1.4 1 0 0 1 1 1 1 DASH complex subunit Dam1 Ctr PF04145.10 CAR26997.1 - 6.4e-30 104.0 4.3 6.4e-30 104.0 3.0 1.8 2 0 0 2 2 2 1 Ctr copper transporter family SH2_2 PF14633.1 CAR26998.1 - 4.5e-104 346.3 4.0 4.5e-104 346.3 2.8 2.0 2 0 0 2 2 2 1 SH2 domain YqgF PF14639.1 CAR26998.1 - 2.4e-64 215.4 0.0 7.3e-64 213.8 0.0 1.9 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 DLD PF14878.1 CAR26998.1 - 2.1e-47 159.9 3.9 1.8e-46 156.9 2.7 2.8 1 0 0 1 1 1 1 Death-like domain of SPT6 HHH_7 PF14635.1 CAR26998.1 - 1.2e-43 147.4 0.0 3.9e-43 145.8 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.1 CAR26998.1 - 6.1e-36 123.0 3.1 6.1e-36 123.0 2.1 2.8 3 0 0 3 3 3 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.1 CAR26998.1 - 6.2e-21 74.3 19.4 6.2e-21 74.3 13.4 5.4 3 1 2 5 5 5 1 Acidic N-terminal SPT6 SH2 PF00017.19 CAR26998.1 - 5.3e-12 45.3 0.3 1.6e-11 43.8 0.1 2.0 2 0 0 2 2 2 1 SH2 domain Aldo_ket_red PF00248.16 CAR26999.1 - 2.9e-40 137.8 0.0 3.3e-40 137.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Mito_carr PF00153.22 CAR27000.1 - 3.6e-56 186.8 4.7 2e-18 65.8 0.1 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein MBD PF01429.14 CAR27000.1 - 0.0069 15.8 0.0 0.021 14.3 0.0 1.8 2 0 0 2 2 2 1 Methyl-CpG binding domain TMEM51 PF15345.1 CAR27001.1 - 1.6 8.3 4.9 2.3 7.8 3.4 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 TRAPP PF04051.11 CAR27002.1 - 7.8e-46 155.3 0.0 1e-45 154.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component GP3 PF03076.9 CAR27002.1 - 0.075 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Equine arteritis virus GP3 MYT1 PF08474.6 CAR27002.1 - 0.12 11.7 1.6 0.2 11.0 1.1 1.2 1 0 0 1 1 1 0 Myelin transcription factor 1 Acetyltransf_1 PF00583.19 CAR27003.1 - 7.6e-17 61.1 0.0 1.5e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CAR27003.1 - 3.6e-05 23.8 0.0 5.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CAR27003.1 - 6e-05 22.7 0.0 9.3e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 CAR27003.1 - 0.0014 18.7 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CAR27003.1 - 0.0031 17.3 0.0 0.0052 16.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 CAR27003.1 - 0.058 12.9 0.1 0.099 12.2 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CAR27003.1 - 0.077 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Metallophos_2 PF12850.2 CAR27004.1 - 1.7e-16 60.4 0.0 2.7e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Spore_coat_CotO PF14153.1 CAR27004.1 - 0.024 14.0 13.9 0.033 13.6 9.6 1.2 1 0 0 1 1 1 0 Spore coat protein CotO GAGA_bind PF06217.7 CAR27004.1 - 0.23 11.4 9.0 0.34 10.8 6.2 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family PPP4R2 PF09184.6 CAR27004.1 - 2.1 7.8 25.6 4 6.9 17.7 1.4 1 0 0 1 1 1 0 PPP4R2 Kei1 PF08552.6 CAR27004.1 - 2.4 7.7 5.9 4.8 6.7 4.1 1.5 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DDHD PF02862.12 CAR27004.1 - 2.6 7.7 9.5 4.4 7.0 6.6 1.4 1 0 0 1 1 1 0 DDHD domain DUF1510 PF07423.6 CAR27004.1 - 3.6 6.8 31.2 5.2 6.3 21.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Membralin PF09746.4 CAR27004.1 - 7 5.5 6.7 30 3.4 4.1 1.9 2 0 0 2 2 2 0 Tumour-associated protein BUD22 PF09073.5 CAR27004.1 - 7.8 5.4 27.2 10 5.0 18.8 1.1 1 0 0 1 1 1 0 BUD22 Ebola_NP PF05505.7 CAR27004.1 - 9 4.2 17.4 11 3.8 12.1 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Ycf1 PF05758.7 CAR27004.1 - 9.6 3.7 17.7 12 3.4 12.3 1.0 1 0 0 1 1 1 0 Ycf1 tRNA-synt_2b PF00587.20 CAR27005.1 - 6.4e-25 87.7 0.0 1.2e-24 86.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 CAR27005.1 - 1.6e-05 24.8 6.9 1.6e-05 24.8 4.8 1.6 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain TBPIP PF07106.8 CAR27005.1 - 0.0014 18.1 3.2 0.0028 17.2 2.2 1.5 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Dynamitin PF04912.9 CAR27005.1 - 0.0038 16.0 3.6 0.0059 15.4 2.5 1.2 1 0 0 1 1 1 1 Dynamitin ATG16 PF08614.6 CAR27005.1 - 0.016 15.0 5.6 0.032 14.0 3.9 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) YlqD PF11068.3 CAR27005.1 - 0.034 14.1 2.5 0.083 12.9 1.7 1.7 1 0 0 1 1 1 0 YlqD protein DUF4407 PF14362.1 CAR27005.1 - 0.082 11.8 0.1 2.3 7.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Spc7 PF08317.6 CAR27005.1 - 0.14 10.7 8.5 0.22 10.1 5.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TACC PF05010.9 CAR27005.1 - 0.19 11.4 7.0 0.3 10.8 4.8 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) Baculo_PEP_C PF04513.7 CAR27005.1 - 0.26 11.0 2.9 0.55 10.0 2.0 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG5 PF10392.4 CAR27005.1 - 0.36 10.7 6.8 0.33 10.9 0.6 2.2 1 1 1 2 2 2 0 Golgi transport complex subunit 5 IncA PF04156.9 CAR27005.1 - 0.53 9.8 10.7 0.9 9.0 7.4 1.3 1 0 0 1 1 1 0 IncA protein DUF342 PF03961.8 CAR27005.1 - 2 6.7 6.0 3.1 6.1 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF964 PF06133.6 CAR27005.1 - 2.4 8.2 8.8 1.5 8.8 4.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF964) Ribosomal_L27e PF01777.13 CAR27006.1 - 2.8e-37 126.6 5.3 3.8e-37 126.2 3.7 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 CAR27006.1 - 0.00029 20.4 1.6 0.0006 19.4 1.1 1.6 1 0 0 1 1 1 1 KOW motif Ndr PF03096.9 CAR27006.1 - 0.13 10.7 0.0 0.23 9.8 0.0 1.4 1 0 0 1 1 1 0 Ndr family AAA_27 PF13514.1 CAR27007.1 - 4.9e-05 21.2 15.8 5.6e-05 21.0 11.0 1.1 1 0 0 1 1 1 1 AAA domain Seryl_tRNA_N PF02403.17 CAR27007.1 - 0.011 15.7 13.3 0.84 9.6 5.6 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Tropomyosin_1 PF12718.2 CAR27007.1 - 0.11 12.3 20.7 0.68 9.7 12.8 2.5 1 1 1 2 2 2 0 Tropomyosin like V_ATPase_I PF01496.14 CAR27007.1 - 0.12 10.1 8.7 0.16 9.7 6.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 CAR27007.1 - 0.14 11.7 22.4 0.53 9.8 14.2 2.1 1 1 1 2 2 2 0 IncA protein Occludin_ELL PF07303.8 CAR27007.1 - 0.14 12.8 14.4 0.26 12.0 7.4 2.6 1 1 1 2 2 2 0 Occludin homology domain SpecificRecomb PF10136.4 CAR27007.1 - 0.19 9.7 8.0 0.18 9.7 4.8 1.3 1 1 1 2 2 2 0 Site-specific recombinase AAA_23 PF13476.1 CAR27007.1 - 0.33 11.2 11.3 0.49 10.6 7.8 1.3 1 0 0 1 1 1 0 AAA domain ADIP PF11559.3 CAR27007.1 - 0.35 10.7 21.5 9.3 6.1 14.5 2.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding GAS PF13851.1 CAR27007.1 - 0.56 9.3 25.7 1 8.4 0.9 2.4 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Penicil_amidase PF01804.13 CAR27007.1 - 0.82 8.6 5.4 1.4 7.8 3.7 1.4 1 1 0 1 1 1 0 Penicillin amidase FUSC PF04632.7 CAR27007.1 - 0.9 7.8 4.5 1.1 7.6 3.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2852 PF11014.3 CAR27007.1 - 1.2 9.1 5.8 16 5.4 3.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) Bap31 PF05529.7 CAR27007.1 - 1.3 8.4 13.7 0.69 9.3 5.9 2.2 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like TMF_TATA_bd PF12325.3 CAR27007.1 - 3 7.5 22.4 6.2 6.5 10.4 2.7 2 1 1 3 3 2 0 TATA element modulatory factor 1 TATA binding EMP24_GP25L PF01105.19 CAR27007.1 - 3.3 7.3 12.0 3.2 7.4 4.9 2.7 1 1 2 3 3 3 0 emp24/gp25L/p24 family/GOLD Muted PF14942.1 CAR27007.1 - 3.4 7.5 18.0 1.4 8.8 10.4 2.0 2 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein Atg14 PF10186.4 CAR27007.1 - 3.5 6.4 18.4 13 4.6 12.8 1.7 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Fib_alpha PF08702.5 CAR27007.1 - 5.6 7.0 19.8 0.68 10.0 7.0 2.8 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.3 CAR27007.1 - 6 6.7 19.1 4.7 7.0 6.6 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Allexi_40kDa PF05549.6 CAR27007.1 - 6.3 6.0 11.8 4.1 6.6 4.6 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF342 PF03961.8 CAR27007.1 - 6.4 5.0 12.1 11 4.3 5.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Ax_dynein_light PF10211.4 CAR27007.1 - 8.1 6.2 18.5 12 5.6 6.1 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain FlxA PF14282.1 CAR27007.1 - 8.9 6.3 19.8 0.56 10.1 9.2 2.1 1 1 1 2 2 2 0 FlxA-like protein Mito_carr PF00153.22 CAR27008.1 - 2.2e-11 43.3 0.0 0.014 15.1 0.0 4.2 4 0 0 4 4 4 4 Mitochondrial carrier protein Dpy-30 PF05186.8 CAR27009.1 - 5.4e-17 60.9 0.0 7.4e-17 60.5 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif SNARE PF05739.14 CAR27010.1 - 1.2e-13 50.4 4.7 1.2e-13 50.4 3.2 2.8 3 0 0 3 3 3 1 SNARE domain Syntaxin-6_N PF09177.6 CAR27010.1 - 8.6e-06 26.0 4.0 8.6e-06 26.0 2.8 3.3 2 1 1 3 3 3 1 Syntaxin 6, N-terminal Prefoldin_2 PF01920.15 CAR27010.1 - 0.0081 15.9 4.5 0.16 11.7 0.9 2.9 2 1 0 2 2 2 1 Prefoldin subunit PhoU_div PF01865.11 CAR27010.1 - 0.015 14.4 7.1 0.36 9.9 0.5 2.3 1 1 0 2 2 2 0 Protein of unknown function DUF47 HisKA_3 PF07730.8 CAR27010.1 - 0.015 15.5 1.6 0.42 10.9 0.1 2.7 2 1 0 2 2 2 0 Histidine kinase Peptidase_M4 PF01447.13 CAR27010.1 - 0.016 15.3 0.5 0.029 14.4 0.2 1.5 1 1 0 1 1 1 0 Thermolysin metallopeptidase, catalytic domain RmuC PF02646.11 CAR27010.1 - 0.018 13.9 8.4 0.018 13.9 0.4 2.3 2 1 0 2 2 2 0 RmuC family Baculo_PEP_C PF04513.7 CAR27010.1 - 0.076 12.8 8.7 1.1 9.0 2.0 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 CAR27010.1 - 0.077 13.2 8.7 0.2 11.9 0.3 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.6 CAR27010.1 - 0.1 12.4 0.3 0.1 12.4 0.2 3.2 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF948) DASH_Dad1 PF08649.5 CAR27010.1 - 0.17 11.6 5.8 4.8 6.9 0.0 3.0 3 0 0 3 3 3 0 DASH complex subunit Dad1 DUF4250 PF14056.1 CAR27010.1 - 0.23 11.1 2.6 2.1 8.1 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) Put_Phosphatase PF06888.7 CAR27010.1 - 0.26 10.4 3.0 0.46 9.6 0.4 2.1 2 1 0 2 2 2 0 Putative Phosphatase DUF745 PF05335.8 CAR27010.1 - 0.3 10.5 8.0 1.1 8.7 1.9 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF745) Microtub_assoc PF07989.6 CAR27010.1 - 0.39 10.5 7.1 0.24 11.2 0.4 2.8 2 1 0 2 2 2 0 Microtubule associated DUF1664 PF07889.7 CAR27010.1 - 0.49 10.2 6.2 4.7 7.0 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) L1R_F9L PF02442.12 CAR27010.1 - 0.5 9.8 4.0 9.6 5.6 1.3 2.4 2 1 0 2 2 2 0 Lipid membrane protein of large eukaryotic DNA viruses Sec20 PF03908.8 CAR27010.1 - 0.69 9.6 4.7 0.59 9.8 0.2 2.3 2 1 0 2 2 2 0 Sec20 Laminin_II PF06009.7 CAR27010.1 - 0.75 9.5 9.1 3.8 7.2 2.7 2.4 2 1 0 2 2 2 0 Laminin Domain II WXG100 PF06013.7 CAR27010.1 - 1.1 9.2 6.0 13 5.8 0.2 3.0 3 1 0 3 3 2 0 Proteins of 100 residues with WXG V-SNARE_C PF12352.3 CAR27010.1 - 1.1 9.3 7.3 0.54 10.3 1.9 2.7 2 1 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Nup88 PF10168.4 CAR27010.1 - 1.1 6.9 8.9 0.069 10.9 1.7 1.8 1 1 1 2 2 2 0 Nuclear pore component DUF4208 PF13907.1 CAR27010.1 - 1.4 9.1 6.1 1.7 8.8 0.3 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4208) Fzo_mitofusin PF04799.8 CAR27010.1 - 1.5 8.2 9.8 0.35 10.2 1.1 2.3 1 1 2 3 3 3 0 fzo-like conserved region Syntaxin PF00804.20 CAR27010.1 - 1.9 8.7 11.8 0.12 12.4 2.0 2.9 1 1 1 2 2 2 0 Syntaxin Bravo_FIGEY PF13882.1 CAR27010.1 - 2.6 9.0 6.0 1.8 9.5 1.2 2.2 2 0 0 2 2 2 0 Bravo-like intracellular region Muted PF14942.1 CAR27010.1 - 4.9 7.0 12.4 0.94 9.3 0.6 2.9 2 1 1 3 3 3 0 Organelle biogenesis, Muted-like protein COG2 PF06148.6 CAR27010.1 - 5.4 6.8 9.3 6.8 6.5 0.5 2.9 2 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2959 PF11172.3 CAR27010.1 - 7.7 6.2 10.9 0.88 9.2 0.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2959) Enkurin PF13864.1 CAR27010.1 - 8.4 6.6 11.8 0.62 10.3 0.3 3.1 2 1 1 3 3 3 0 Calmodulin-binding DAO PF01266.19 CAR27011.1 - 1.4e-66 224.8 0.0 2.4e-65 220.8 0.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CAR27011.1 - 9.1e-07 28.8 0.0 4.8e-06 26.5 0.0 2.2 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CAR27011.1 - 0.0012 18.0 0.1 0.0022 17.1 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Strep_67kDa_ant PF06100.6 CAR27011.1 - 0.015 13.6 0.1 0.023 13.0 0.1 1.2 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family NAD_binding_9 PF13454.1 CAR27011.1 - 0.03 14.1 0.2 0.094 12.4 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 CAR27011.1 - 0.037 12.6 0.0 0.14 10.7 0.1 1.8 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 CAR27011.1 - 0.063 13.3 0.0 0.44 10.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CAR27011.1 - 0.081 13.3 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Saccharop_dh PF03435.13 CAR27011.1 - 0.087 11.7 0.1 0.17 10.8 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase Cwf_Cwc_15 PF04889.7 CAR27011.1 - 0.11 12.2 11.2 0.15 11.7 7.8 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Ebola_NP PF05505.7 CAR27011.1 - 2.7 5.9 7.9 3.5 5.5 5.5 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Pkinase PF00069.20 CAR27012.1 - 2.1e-63 213.9 0.0 3.3e-63 213.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR27012.1 - 1.1e-33 116.3 0.0 1.7e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR27012.1 - 1.1e-08 34.3 0.0 1.8e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CAR27012.1 - 0.00012 21.9 0.1 0.0004 20.1 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CAR27012.1 - 0.0059 15.9 0.0 0.018 14.4 0.0 1.7 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.9 CAR27012.1 - 0.05 12.6 0.0 0.087 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sod_Fe_C PF02777.13 CAR27013.1 - 4e-37 126.2 0.5 7.7e-37 125.3 0.4 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 CAR27013.1 - 5.2e-26 90.7 0.5 1.1e-25 89.6 0.3 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain VCBS PF13517.1 CAR27013.1 - 0.092 13.1 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Methyltransf_11 PF08241.7 CAR27014.1 - 0.0082 16.6 0.0 0.024 15.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CAR27014.1 - 0.049 12.6 0.1 0.13 11.2 0.0 1.6 1 1 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.13 CAR27014.1 - 0.096 11.8 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase CENP-T PF15511.1 CAR27014.1 - 3.2 6.9 11.2 4.6 6.3 7.7 1.3 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T NUDIX PF00293.23 CAR27016.1 - 6.6e-18 64.6 0.1 7.7e-18 64.4 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain DUF410 PF04190.8 CAR27017.1 - 6.2e-79 265.2 3.6 7.2e-79 264.9 2.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) RHD3 PF05879.7 CAR27018.1 - 6.8e-241 801.2 15.5 8.4e-241 800.9 10.7 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.18 CAR27018.1 - 1.6e-05 24.7 0.4 7.5e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 CAR27018.1 - 0.0004 20.3 0.0 0.0013 18.7 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CAR27018.1 - 0.0013 19.1 0.0 0.0046 17.4 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 CAR27018.1 - 0.054 13.4 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain HTH_Crp_2 PF13545.1 CAR27018.1 - 0.065 13.0 0.3 0.74 9.6 0.1 2.4 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain AAA_22 PF13401.1 CAR27018.1 - 0.15 12.2 2.6 2.1 8.5 0.0 3.4 2 2 1 3 3 3 0 AAA domain YbfN PF13982.1 CAR27018.1 - 0.33 11.1 2.5 1.8 8.8 0.1 3.2 3 0 0 3 3 3 0 YbfN-like lipoprotein PIN_4 PF13638.1 CAR27020.1 - 4.4e-30 104.5 0.1 9e-30 103.5 0.1 1.5 1 0 0 1 1 1 1 PIN domain Red1 PF07964.6 CAR27021.1 - 1e-148 496.6 37.0 3.8e-76 256.7 24.8 2.4 1 1 1 2 2 2 2 Rec10 / Red1 tRNA-synt_1c PF00749.16 CAR27022.1 - 5.5e-112 373.4 0.0 8.2e-112 372.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.10 CAR27022.1 - 2.5e-51 173.4 2.1 4.1e-51 172.7 1.4 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.13 CAR27022.1 - 1.9e-30 105.8 0.1 3.4e-29 101.7 0.0 2.4 1 1 1 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.10 CAR27022.1 - 3.2e-18 66.2 4.7 8.9e-18 64.7 3.2 1.8 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 TMA7 PF09072.5 CAR27023.1 - 4.8e-21 74.9 20.3 5.3e-21 74.8 14.0 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Ras PF00071.17 CAR27024.1 - 1.6e-57 193.3 0.4 2e-57 193.1 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR27024.1 - 2.9e-22 79.4 0.2 6.6e-22 78.2 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CAR27024.1 - 2.9e-16 59.1 0.2 3.6e-16 58.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CAR27024.1 - 9.1e-06 25.6 0.0 1.8e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CAR27024.1 - 2.3e-05 23.7 0.0 4.9e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 CAR27024.1 - 2.9e-05 23.6 0.0 0.00015 21.2 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CAR27024.1 - 3.2e-05 23.1 0.1 4.1e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arch_ATPase PF01637.13 CAR27024.1 - 0.0014 18.3 0.5 0.0052 16.5 0.0 1.9 1 1 1 2 2 2 1 Archaeal ATPase PduV-EutP PF10662.4 CAR27024.1 - 0.0026 17.2 0.5 0.021 14.2 0.3 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 CAR27024.1 - 0.0032 17.6 0.0 0.015 15.4 0.0 2.0 1 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 CAR27024.1 - 0.018 14.2 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 CAR27024.1 - 0.02 14.4 0.1 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CAR27024.1 - 0.041 13.8 0.0 0.095 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 CAR27024.1 - 0.09 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Tenui_NCP PF04876.7 CAR27024.1 - 0.097 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Tenuivirus major non-capsid protein DAGK_cat PF00781.19 CAR27025.1 - 5e-26 90.6 0.0 1.1e-25 89.5 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Herpes_LMP1 PF05297.6 CAR27025.1 - 0.05 12.5 2.6 0.071 12.0 1.8 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Imm41 PF15583.1 CAR27025.1 - 0.06 13.1 0.3 0.14 11.9 0.2 1.5 1 0 0 1 1 1 0 Immunity protein 41 Cpn60_TCP1 PF00118.19 CAR27026.1 - 1.5e-114 383.3 8.9 1.7e-114 383.1 6.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Img2 PF05046.9 CAR27027.1 - 0.13 12.5 2.3 0.14 12.3 0.3 2.1 2 0 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) RNA_pol_I_TF PF04090.7 CAR27028.1 - 1.2e-70 236.8 0.1 1.9e-70 236.2 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase I specific initiation factor DUF2483 PF10656.4 CAR27028.1 - 0.025 14.6 0.1 0.1 12.6 0.0 2.0 2 0 0 2 2 2 0 Hypothetical protein of unknown function (DUF2483) zf-RING_2 PF13639.1 CAR27029.1 - 1.9e-10 40.3 9.6 1.2e-09 37.8 6.7 2.2 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CAR27029.1 - 3.3e-08 33.5 3.1 6.8e-08 32.5 2.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CAR27029.1 - 8.9e-07 28.4 2.4 3.2e-06 26.6 1.7 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CAR27029.1 - 4.2e-06 26.3 7.3 2.4e-05 23.8 5.1 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAR27029.1 - 7.2e-06 25.6 3.7 1.6e-05 24.5 2.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CAR27029.1 - 1.4e-05 24.9 2.5 1.4e-05 24.9 1.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF4457 PF14652.1 CAR27029.1 - 0.0031 16.5 0.0 0.032 13.2 0.0 2.0 1 1 0 2 2 2 1 Domain of unknown function (DUF4457) zf-RING_UBOX PF13445.1 CAR27029.1 - 0.0044 16.7 1.8 0.0044 16.7 1.3 3.1 4 1 0 4 4 4 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CAR27029.1 - 0.0058 16.4 5.6 0.19 11.6 1.1 2.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Rtf2 PF04641.7 CAR27029.1 - 0.01 15.0 0.1 0.016 14.3 0.1 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger zf-Apc11 PF12861.2 CAR27029.1 - 0.022 14.6 0.5 0.022 14.6 0.3 1.6 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Dicty_REP PF05086.7 CAR27029.1 - 0.076 10.7 13.3 0.034 11.9 6.9 1.9 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein Prok-RING_4 PF14447.1 CAR27029.1 - 0.076 12.5 0.3 0.21 11.1 0.2 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF3272 PF11676.3 CAR27029.1 - 0.078 12.9 2.1 0.37 10.8 1.5 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3272) Mucin PF01456.12 CAR27029.1 - 0.34 10.6 31.5 0.76 9.5 21.8 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein zf-RING_4 PF14570.1 CAR27029.1 - 0.54 9.8 5.7 0.065 12.8 0.4 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Histone PF00125.19 CAR27030.1 - 5e-22 77.8 0.0 6.4e-22 77.4 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CAR27030.1 - 0.0014 18.6 0.0 0.0019 18.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PLA2_B PF01735.13 CAR27031.1 - 4e-214 711.3 1.8 4.7e-214 711.0 1.3 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain TAF4 PF05236.9 CAR27032.1 - 9.4e-70 234.8 1.8 9.4e-70 234.8 1.3 1.5 2 0 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family TFIID_30kDa PF03540.8 CAR27032.1 - 0.018 14.8 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit GCV_T_C PF08669.6 CAR27032.1 - 0.036 14.0 0.1 0.072 13.1 0.1 1.5 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain SopA PF13981.1 CAR27032.1 - 0.1 12.6 0.2 0.24 11.3 0.1 1.6 1 1 0 1 1 1 0 SopA-like central domain RTC PF01137.16 CAR27033.1 - 2.8e-60 202.9 0.0 3.4e-60 202.6 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 CAR27033.1 - 3.8e-32 110.3 0.0 6.5e-32 109.6 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain PX PF00787.19 CAR27034.1 - 3.2e-21 75.2 0.2 6.9e-21 74.1 0.1 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 CAR27034.1 - 0.0014 17.9 0.2 0.0022 17.2 0.1 1.3 1 0 0 1 1 1 1 Vps5 C terminal like DUF2404 PF10296.4 CAR27035.1 - 0.00031 20.8 0.0 0.0016 18.5 0.0 2.0 1 1 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) Polyketide_cyc PF03364.15 CAR27036.1 - 9.6e-17 61.1 0.1 1.2e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 CAR27036.1 - 0.032 14.4 0.0 0.05 13.7 0.0 1.3 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport SAP PF02037.22 CAR27037.1 - 1.4e-10 40.4 1.8 2.6e-10 39.5 1.2 1.4 1 0 0 1 1 1 1 SAP domain DUF1913 PF08931.5 CAR27037.1 - 0.03 14.1 0.2 0.05 13.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1913) Mac-1 PF09028.5 CAR27037.1 - 0.084 11.6 0.2 0.15 10.8 0.1 1.3 2 0 0 2 2 2 0 Mac 1 DUF2076 PF09849.4 CAR27038.1 - 2.7e-08 34.1 10.2 3.7e-08 33.7 7.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 CAR27038.1 - 0.00027 20.7 5.0 0.00041 20.1 3.0 1.7 1 1 1 2 2 2 1 CHCH domain Gly-zipper_OmpA PF13436.1 CAR27038.1 - 0.0029 17.2 4.6 0.0059 16.2 3.2 1.6 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain RAB3GAP2_N PF14655.1 CAR27038.1 - 0.027 13.5 0.1 0.03 13.3 0.1 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF605 PF04652.11 CAR27038.1 - 0.079 12.3 8.6 0.092 12.1 5.9 1.1 1 0 0 1 1 1 0 Vta1 like Nucleoporin_FG PF13634.1 CAR27038.1 - 0.29 11.3 15.8 0.43 10.8 11.0 1.3 1 0 0 1 1 1 0 Nucleoporin FG repeat region COX6B PF02297.12 CAR27038.1 - 0.35 10.9 5.6 0.64 10.0 3.9 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb PAT1 PF09770.4 CAR27038.1 - 1.8 6.6 12.3 2.2 6.4 8.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HD-ZIP_N PF04618.7 CAR27038.1 - 3 8.4 8.1 1.5 9.3 0.2 2.2 1 1 1 2 2 2 0 HD-ZIP protein N terminus TFIIA PF03153.8 CAR27038.1 - 4.5 7.0 9.6 5.3 6.8 6.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Topoisom_I_N PF02919.10 CAR27040.1 - 6.8e-100 332.7 1.1 6.8e-100 332.7 0.8 4.4 4 2 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 CAR27040.1 - 6.5e-85 283.9 3.4 6.5e-85 283.9 2.4 3.4 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 CAR27040.1 - 2.1e-32 110.5 0.2 1.1e-31 108.2 0.1 2.4 1 0 0 1 1 1 1 C-terminal topoisomerase domain Mucin PF01456.12 CAR27040.1 - 3.8 7.2 18.2 7.2 6.3 12.6 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Pkinase PF00069.20 CAR27041.1 - 4e-72 242.5 0.0 6.5e-72 241.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR27041.1 - 7.6e-40 136.6 0.0 1.1e-39 136.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 CAR27041.1 - 2e-34 117.3 0.1 1.6e-17 63.2 0.0 2.7 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 CAR27041.1 - 1.1e-09 37.6 0.0 1.4e-08 34.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like SH3_3 PF08239.6 CAR27041.1 - 0.00052 20.1 0.1 0.001 19.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain Kdo PF06293.9 CAR27041.1 - 0.0022 17.1 0.0 0.0043 16.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RNA_pol_L_2 PF13656.1 CAR27042.1 - 3.4e-25 87.2 0.0 4.4e-25 86.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 CAR27042.1 - 7.4e-11 41.0 0.0 1e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain PAH PF02671.16 CAR27043.1 - 7.5e-49 163.1 6.1 1e-18 66.6 0.4 3.7 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 CAR27043.1 - 6.9e-43 144.5 0.4 2.5e-42 142.7 0.3 2.1 1 0 0 1 1 1 1 Sin3 family co-repressor zf-DHHC PF01529.15 CAR27044.1 - 8.4e-32 109.9 14.1 8.4e-32 109.9 9.8 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 CAR27044.1 - 0.032 14.0 0.8 0.054 13.2 0.5 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily HlyIII PF03006.15 CAR27045.1 - 1.6e-52 178.1 21.7 1.9e-52 177.8 15.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF981 PF06168.6 CAR27045.1 - 0.1 12.3 6.6 0.012 15.3 1.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF981) DUF4231 PF14015.1 CAR27045.1 - 0.16 11.9 1.4 0.6 10.1 0.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) DHC_N2 PF08393.8 CAR27045.1 - 0.36 9.2 4.7 0.78 8.1 0.2 2.0 2 0 0 2 2 2 0 Dynein heavy chain, N-terminal region 2 Cyclin PF08613.6 CAR27046.1 - 4.4e-33 114.8 1.6 8e-33 113.9 1.1 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CAR27046.1 - 0.00071 19.1 0.2 0.0013 18.3 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain DNA_pol_A_exo1 PF01612.15 CAR27047.1 - 2.9e-45 153.8 0.4 6e-45 152.8 0.3 1.6 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 CAR27047.1 - 4.3e-28 97.4 3.5 5.8e-26 90.6 0.3 3.1 2 0 0 2 2 2 2 PMC2NT (NUC016) domain HRDC PF00570.18 CAR27047.1 - 6.1e-10 38.6 0.0 2e-09 36.9 0.0 2.0 1 0 0 1 1 1 1 HRDC domain Ras PF00071.17 CAR27048.1 - 9.3e-58 194.1 0.6 1.1e-57 193.9 0.4 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR27048.1 - 7.2e-19 68.4 0.1 1.6e-18 67.3 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CAR27048.1 - 5.9e-16 58.1 0.1 6.9e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CAR27048.1 - 3e-08 33.0 0.1 3.4e-08 32.9 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CAR27048.1 - 3e-08 33.3 0.4 7.6e-07 28.7 0.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CAR27048.1 - 2.4e-06 26.8 0.2 3.2e-06 26.4 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CAR27048.1 - 8e-06 25.7 0.0 1.1e-05 25.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CAR27048.1 - 4e-05 23.7 0.0 8.2e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 CAR27048.1 - 5.9e-05 22.7 0.6 0.0015 18.1 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 CAR27048.1 - 0.00017 21.5 0.1 0.011 15.7 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.1 CAR27048.1 - 0.0015 18.1 0.6 0.0069 15.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 CAR27048.1 - 0.0039 16.3 0.1 0.0097 15.1 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 NTPase_1 PF03266.10 CAR27048.1 - 0.0046 16.6 0.1 0.014 15.0 0.0 1.8 2 0 0 2 2 2 1 NTPase PduV-EutP PF10662.4 CAR27048.1 - 0.0079 15.6 0.7 0.1 12.0 0.5 2.3 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 CAR27048.1 - 0.011 15.2 0.1 0.04 13.3 0.0 1.8 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 CAR27048.1 - 0.011 15.4 0.1 0.024 14.3 0.0 1.7 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 CAR27048.1 - 0.011 15.4 0.4 0.026 14.2 0.2 1.9 1 1 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 CAR27048.1 - 0.015 14.9 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.17 CAR27048.1 - 0.061 12.1 0.2 0.14 11.0 0.0 1.5 1 1 0 1 1 1 0 NB-ARC domain Septin PF00735.13 CAR27048.1 - 0.063 12.2 0.2 0.26 10.2 0.0 1.9 2 0 0 2 2 2 0 Septin Bac_DnaA PF00308.13 CAR27048.1 - 0.076 12.6 0.1 0.14 11.7 0.0 1.4 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_10 PF12846.2 CAR27048.1 - 0.081 12.3 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_35 PF14516.1 CAR27048.1 - 0.096 11.3 0.0 0.25 9.9 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain PRK PF00485.13 CAR27048.1 - 0.11 12.0 0.1 0.17 11.4 0.0 1.6 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_5 PF07728.9 CAR27048.1 - 0.14 11.9 0.0 0.47 10.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Pirin PF02678.11 CAR27049.1 - 1.6e-26 92.2 0.0 4.4e-26 90.8 0.0 1.7 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.8 CAR27049.1 - 7.6e-19 67.7 0.0 1.9e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 CAR27049.1 - 0.0045 16.4 0.3 0.09 12.2 0.2 2.4 2 0 0 2 2 2 1 Cupin domain Alg6_Alg8 PF03155.10 CAR27050.1 - 6.3e-163 542.9 31.6 7.5e-163 542.6 21.9 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family TPR_11 PF13414.1 CAR27051.1 - 8.5e-24 82.9 8.0 2.2e-17 62.4 1.2 3.5 2 1 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 CAR27051.1 - 8.9e-19 66.2 7.3 1.7e-06 27.3 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 CAR27051.1 - 1.7e-18 64.9 5.6 0.00012 21.7 0.1 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 CAR27051.1 - 8.4e-09 35.8 5.4 4.9e-05 23.8 1.0 2.9 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CAR27051.1 - 5.6e-08 32.6 9.3 1.8e-07 31.0 1.3 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 CAR27051.1 - 8.3e-08 31.8 1.6 0.0055 16.8 0.1 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CAR27051.1 - 6.4e-06 26.4 4.4 0.022 15.0 0.1 3.7 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CAR27051.1 - 6.7e-06 26.2 0.2 0.76 10.5 0.0 4.1 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 CAR27051.1 - 1.6e-05 24.3 4.5 0.071 12.9 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 CAR27051.1 - 2.2e-05 23.9 14.5 0.0037 16.9 0.3 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 CAR27051.1 - 0.0045 17.3 6.3 0.032 14.7 0.1 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 CAR27051.1 - 0.0072 16.2 2.6 5.3 7.1 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CAR27051.1 - 0.0073 16.4 2.3 0.0073 16.4 1.6 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.12 CAR27051.1 - 0.018 15.3 0.2 0.13 12.5 0.0 2.3 1 1 1 2 2 2 0 Bacterial transcriptional activator domain RPN7 PF10602.4 CAR27051.1 - 0.087 12.1 2.9 0.063 12.6 0.6 1.8 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TPR_9 PF13371.1 CAR27051.1 - 0.09 12.6 0.2 7 6.5 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CAR27051.1 - 0.11 12.4 3.1 13 5.7 0.1 3.4 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat DUF3856 PF12968.2 CAR27051.1 - 0.45 10.3 4.3 2.2 8.1 0.3 3.5 2 1 1 4 4 4 0 Domain of Unknown Function (DUF3856) VPS9 PF02204.13 CAR27052.1 - 6.6e-12 45.3 0.3 1.4e-10 41.0 0.1 2.9 3 0 0 3 3 3 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.1 CAR27052.1 - 1.1e-07 31.8 0.0 0.0014 18.8 0.0 4.4 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CAR27052.1 - 2.9e-05 24.3 0.7 0.021 15.1 0.5 3.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CAR27052.1 - 0.0017 18.7 0.2 0.12 12.9 0.1 3.5 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.25 CAR27052.1 - 0.0079 15.9 0.0 1.3 8.9 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat DUF367 PF04034.8 CAR27053.1 - 3.4e-52 175.3 0.0 4.8e-52 174.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 CAR27053.1 - 2.6e-14 52.5 0.2 4.5e-14 51.7 0.1 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_23 PF13476.1 CAR27053.1 - 0.0077 16.5 1.0 0.01 16.1 0.7 1.3 1 0 0 1 1 1 1 AAA domain CDC45 PF02724.9 CAR27053.1 - 0.012 13.7 6.3 0.016 13.2 4.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_60s PF00428.14 CAR27053.1 - 0.06 13.7 15.0 0.11 12.9 10.4 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Nucleoplasmin PF03066.10 CAR27053.1 - 0.14 11.6 16.8 0.24 10.9 11.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin Na_trans_assoc PF06512.8 CAR27053.1 - 0.33 10.8 15.1 0.1 12.5 7.2 1.9 2 0 0 2 2 2 0 Sodium ion transport-associated Nop14 PF04147.7 CAR27053.1 - 0.83 7.4 17.3 1.1 7.0 12.0 1.2 1 0 0 1 1 1 0 Nop14-like family BSP_II PF05432.6 CAR27053.1 - 1.3 8.2 20.4 2.1 7.5 14.2 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) RXT2_N PF08595.6 CAR27053.1 - 1.7 8.4 10.4 2.7 7.7 7.2 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Myc_N PF01056.13 CAR27053.1 - 2.1 7.4 15.2 3.8 6.5 10.5 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Daxx PF03344.10 CAR27053.1 - 2.5 6.5 20.7 3.6 5.9 14.4 1.2 1 0 0 1 1 1 0 Daxx Family Spore_coat_CotO PF14153.1 CAR27053.1 - 4.4 6.7 14.6 9.5 5.6 10.1 1.6 1 0 0 1 1 1 0 Spore coat protein CotO DNA_ligase_A_M PF01068.16 CAR27054.1 - 2.6e-46 157.5 0.0 4.6e-46 156.7 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 CAR27054.1 - 1.3e-14 54.4 0.0 2.2e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus BRCT PF00533.21 CAR27054.1 - 1e-08 35.2 0.0 2e-06 27.8 0.0 2.7 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_A_C PF04679.10 CAR27054.1 - 1.3e-05 25.5 0.1 3e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_IV PF11411.3 CAR27054.1 - 0.0076 15.9 0.2 0.017 14.8 0.2 1.5 1 0 0 1 1 1 1 DNA ligase IV mRNA_cap_enzyme PF01331.14 CAR27054.1 - 0.16 11.6 3.2 3.6 7.2 1.2 3.2 2 1 0 2 2 2 0 mRNA capping enzyme, catalytic domain NPR2 PF06218.6 CAR27055.1 - 9.8e-169 561.5 6.1 9.8e-169 561.5 4.2 1.8 2 0 0 2 2 2 1 Nitrogen permease regulator 2 NPR3 PF03666.8 CAR27055.1 - 0.00081 18.0 1.5 0.012 14.1 0.0 2.8 3 0 0 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 Kinesin PF00225.18 CAR27056.1 - 4.5e-96 321.4 12.7 8.9e-64 215.2 6.1 3.5 4 0 0 4 4 4 2 Kinesin motor domain Fcf1 PF04900.7 CAR27057.1 - 3.6e-32 110.4 0.3 3.6e-32 110.4 0.2 2.1 3 0 0 3 3 3 1 Fcf1 DUF2201_N PF13203.1 CAR27057.1 - 3.5 6.7 11.8 5 6.2 8.2 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Nucleo_P87 PF07267.6 CAR27057.1 - 8.2 4.9 9.6 10 4.6 6.6 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Peptidase_S8 PF00082.17 CAR27058.1 - 4.3e-52 176.9 7.5 6.7e-52 176.3 5.2 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 CAR27058.1 - 2.2e-09 37.7 0.0 4.5e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Lyase_1 PF00206.15 CAR27059.1 - 4e-118 394.1 0.2 5.1e-118 393.7 0.1 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 CAR27059.1 - 3.4e-25 87.8 0.3 1.4e-23 82.6 0.0 2.5 2 0 0 2 2 2 1 Fumarase C C-terminus ADH_N PF08240.7 CAR27059.1 - 0.043 13.5 0.0 0.093 12.5 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Sulfate_transp PF00916.15 CAR27060.1 - 6.2e-53 179.6 8.3 6.2e-53 179.6 5.8 2.0 2 0 0 2 2 2 1 Sulfate transporter family STAS PF01740.16 CAR27060.1 - 1.8e-16 59.6 1.2 3.7e-16 58.6 0.8 1.6 1 0 0 1 1 1 1 STAS domain cNMP_binding PF00027.24 CAR27060.1 - 3.5e-05 23.5 0.0 9.1e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Adeno_E3_14_5 PF04834.7 CAR27060.1 - 0.18 12.2 1.1 1.2 9.6 0.1 2.8 1 1 1 2 2 2 0 Early E3 14.5 kDa protein SWIRM PF04433.12 CAR27061.1 - 4.8e-31 106.7 0.1 1.1e-30 105.5 0.1 1.7 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 CAR27061.1 - 6.8e-08 32.4 0.1 2e-07 30.9 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CAR27061.1 - 1.9e-07 31.0 0.1 1.9e-07 31.0 0.1 3.2 3 0 0 3 3 3 1 Myb-like DNA-binding domain CASP_C PF08172.7 CAR27062.1 - 1.3e-71 240.5 6.6 1.3e-71 240.5 4.6 4.4 2 1 1 3 3 3 1 CASP C terminal ADIP PF11559.3 CAR27062.1 - 0.0017 18.2 5.1 0.0017 18.2 3.5 6.7 4 1 2 6 6 6 2 Afadin- and alpha -actinin-Binding HAUS-augmin3 PF14932.1 CAR27062.1 - 0.0055 15.9 12.6 0.0055 15.9 8.7 5.2 4 1 1 5 5 5 2 HAUS augmin-like complex subunit 3 NPV_P10 PF05531.7 CAR27062.1 - 0.0056 16.9 1.9 0.0056 16.9 1.3 5.6 4 2 1 5 5 5 1 Nucleopolyhedrovirus P10 protein Mannitol_dh PF01232.18 CAR27062.1 - 6.3 6.7 8.7 0.54 10.2 1.3 2.8 2 1 0 2 2 2 0 Mannitol dehydrogenase Rossmann domain Ribosomal_L22 PF00237.14 CAR27063.1 - 2.2e-32 111.1 0.3 3.5e-32 110.4 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribonuc_L-PSP PF01042.16 CAR27064.1 - 2.1e-40 137.2 0.2 2.4e-40 137.0 0.2 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP RhoGEF PF00621.15 CAR27064.1 - 0.023 14.6 0.7 0.038 13.8 0.5 1.5 1 1 0 1 1 1 0 RhoGEF domain Cyclin PF08613.6 CAR27066.1 - 2.4e-41 141.6 5.1 4.1e-24 85.6 0.0 2.7 3 0 0 3 3 3 2 Cyclin DUF3192 PF11399.3 CAR27066.1 - 0.014 15.3 1.5 0.023 14.6 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3192) P68HR PF08061.6 CAR27066.1 - 0.033 13.9 2.2 0.06 13.0 1.5 1.4 1 0 0 1 1 1 0 P68HR (NUC004) repeat Transp_cyt_pur PF02133.10 CAR27067.1 - 6.7e-87 291.8 36.2 7.7e-87 291.6 25.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ketoacyl-synt PF00109.21 CAR27068.1 - 5.2e-57 193.2 0.0 6.8e-57 192.8 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 CAR27068.1 - 1.8e-29 101.9 0.1 3.5e-29 101.0 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 CAR27068.1 - 0.0037 16.2 0.1 0.0064 15.5 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain HAD_2 PF13419.1 CAR27069.1 - 4.8e-10 39.9 0.0 6.4e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CAR27069.1 - 2.9e-07 31.1 0.0 3.8e-06 27.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CAR27069.1 - 2.2e-05 24.0 0.0 4.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 CAR27069.1 - 0.0042 17.2 0.0 0.0049 17.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase SAP PF02037.22 CAR27070.1 - 6.9e-12 44.5 0.1 1.4e-11 43.5 0.1 1.6 1 0 0 1 1 1 1 SAP domain Daxx PF03344.10 CAR27070.1 - 0.2 10.0 13.6 0.23 9.9 9.4 1.1 1 0 0 1 1 1 0 Daxx Family Spore_coat_CotO PF14153.1 CAR27070.1 - 0.58 9.5 14.6 0.9 8.9 10.1 1.4 1 0 0 1 1 1 0 Spore coat protein CotO eIF-3c_N PF05470.7 CAR27070.1 - 0.59 8.1 11.8 0.72 7.8 8.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF2201_N PF13203.1 CAR27070.1 - 1.8 7.7 11.2 2.6 7.1 7.8 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain TMEM247 PF15444.1 CAR27070.1 - 3.4 7.4 6.9 4.3 7.0 4.8 1.1 1 0 0 1 1 1 0 Transmembrane protein 247 RRN3 PF05327.6 CAR27070.1 - 3.5 5.6 7.0 4.9 5.1 4.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SAPS PF04499.10 CAR27070.1 - 3.6 6.1 10.2 4.6 5.7 7.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ycf1 PF05758.7 CAR27070.1 - 4.5 4.8 13.0 5.3 4.6 9.0 1.0 1 0 0 1 1 1 0 Ycf1 Vhr1 PF04001.8 CAR27072.1 - 1.1e-48 163.1 1.1 2.1e-48 162.1 0.8 1.5 1 0 0 1 1 1 1 Transcription factor Vhr1 ICL PF00463.16 CAR27073.1 - 2.5e-265 880.6 0.4 2.8e-265 880.4 0.3 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 CAR27073.1 - 5.2e-11 42.2 0.1 3.9e-10 39.3 0.0 2.0 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase RIG-I_C-RD PF11648.3 CAR27074.1 - 0.13 12.1 0.1 0.24 11.2 0.0 1.5 1 1 1 2 2 2 0 C-terminal domain of RIG-I DUF2578 PF10843.3 CAR27075.1 - 3.6e-56 189.9 10.5 4e-56 189.7 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2578) zf-RING_4 PF14570.1 CAR27076.1 - 5.3e-20 70.7 13.6 9.7e-20 69.8 9.4 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_5 PF13893.1 CAR27076.1 - 6.1e-06 25.9 0.2 0.034 13.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.6 CAR27076.1 - 7.6e-06 25.7 2.9 1.8e-05 24.5 2.0 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4_3 PF13920.1 CAR27076.1 - 2.8e-05 23.6 7.1 5.6e-05 22.7 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 CAR27076.1 - 0.00011 21.7 0.0 0.016 14.7 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.1 CAR27076.1 - 0.00039 20.1 8.8 0.00083 19.1 6.1 1.6 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.7 CAR27076.1 - 0.00047 19.4 1.2 0.00047 19.4 0.9 2.6 3 0 0 3 3 3 1 Rtf2 RING-finger zf-C3HC4 PF00097.20 CAR27076.1 - 0.0018 17.8 11.2 0.0037 16.8 7.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Med15 PF09606.5 CAR27076.1 - 0.0054 15.0 52.0 0.066 11.4 13.5 2.2 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal SET_assoc PF11767.3 CAR27076.1 - 0.013 14.7 0.0 0.032 13.5 0.0 1.6 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated zf-C3HC4_2 PF13923.1 CAR27076.1 - 0.062 13.3 10.7 0.12 12.4 7.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RRM_6 PF14259.1 CAR27076.1 - 0.14 12.1 0.0 2.5 8.1 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-RING_5 PF14634.1 CAR27076.1 - 0.34 10.6 10.0 0.67 9.7 7.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Peptidase_S49_N PF08496.5 CAR27076.1 - 2.2 8.0 15.3 0.84 9.4 0.1 2.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Suf PF05843.9 CAR27076.1 - 2.5 7.7 17.6 0.14 11.9 4.0 2.8 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) NARP1 PF12569.3 CAR27076.1 - 4.5 5.9 16.9 0.062 12.0 4.9 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 FadA PF09403.5 CAR27076.1 - 5 7.1 15.2 5.4 7.0 1.3 2.5 2 0 0 2 2 2 0 Adhesion protein FadA FAM91_C PF14648.1 CAR27076.1 - 6.5 5.4 8.4 1.7 7.3 3.2 1.8 2 0 0 2 2 2 0 FAM91 C-terminus FYDLN_acid PF09538.5 CAR27076.1 - 7 7.2 10.8 30 5.2 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) PAT1 PF09770.4 CAR27076.1 - 7.3 4.6 48.8 1.9 6.6 15.6 2.3 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DDHD PF02862.12 CAR27076.1 - 8.3 6.1 15.2 1.9 8.1 6.0 2.7 3 0 0 3 3 3 0 DDHD domain zf-C3HC4_4 PF15227.1 CAR27076.1 - 9.2 6.2 12.1 58 3.6 8.4 2.4 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING U1snRNP70_N PF12220.3 CAR27077.1 - 5.5e-21 74.7 2.7 5.5e-21 74.7 1.9 1.7 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 CAR27077.1 - 1.8e-18 65.8 0.0 4e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR27077.1 - 3.7e-13 49.2 0.0 6.7e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR27077.1 - 1.3e-05 24.9 0.0 2.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF619 PF04768.8 CAR27078.1 - 3.2e-52 176.3 0.1 9.4e-52 174.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 CAR27078.1 - 2.3e-27 95.7 0.0 4.8e-27 94.6 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 CAR27078.1 - 3.3e-20 72.6 0.1 5.7e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.15 CAR27078.1 - 0.011 15.6 0.0 0.033 14.1 0.0 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus P16-Arc PF04699.9 CAR27079.1 - 3.7e-52 176.3 0.0 4.1e-52 176.2 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Ran_BP1 PF00638.13 CAR27080.1 - 1.1e-34 119.0 0.1 3.2e-34 117.5 0.1 1.8 1 0 0 1 1 1 1 RanBP1 domain DUF605 PF04652.11 CAR27080.1 - 0.19 11.0 25.1 0.27 10.5 17.4 1.2 1 0 0 1 1 1 0 Vta1 like Methyltransf_31 PF13847.1 CAR27081.1 - 5.7e-25 87.6 0.0 8e-25 87.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR27081.1 - 1.9e-17 63.8 0.0 3e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAR27081.1 - 3e-08 34.0 0.0 5.1e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAR27081.1 - 6e-08 32.9 0.0 8.9e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CAR27081.1 - 3.7e-07 30.2 0.0 6.6e-07 29.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CAR27081.1 - 7.7e-06 25.3 0.0 1.1e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 CAR27081.1 - 3.1e-05 24.3 0.0 4.9e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 CAR27081.1 - 6.3e-05 22.6 0.0 9.9e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CAR27081.1 - 0.00013 21.2 0.0 0.00015 20.9 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 CAR27081.1 - 0.00045 19.9 0.0 0.0007 19.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 CAR27081.1 - 0.0057 16.0 0.0 0.0089 15.4 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW TehB PF03848.9 CAR27081.1 - 0.01 14.9 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB DUF2396 PF09654.5 CAR27081.1 - 0.061 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2396) Methyltransf_4 PF02390.12 CAR27081.1 - 0.11 11.5 0.0 0.2 10.6 0.0 1.5 2 0 0 2 2 2 0 Putative methyltransferase Fis1_TPR_C PF14853.1 CAR27082.1 - 3.1e-26 91.0 0.1 4.4e-26 90.4 0.1 1.2 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 CAR27082.1 - 1.5e-14 52.9 0.0 2.4e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_19 PF14559.1 CAR27082.1 - 0.0032 17.7 0.0 0.007 16.6 0.0 1.5 2 0 0 2 2 2 1 Tetratricopeptide repeat SKG6 PF08693.5 CAR27082.1 - 0.0093 15.2 0.6 0.016 14.5 0.4 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Ribonuc_red_lgC PF02867.10 CAR27083.1 - 8.2e-215 714.4 0.0 1.1e-214 714.0 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 CAR27083.1 - 5.1e-22 77.4 0.0 1.3e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 CAR27083.1 - 7.6e-17 61.5 0.0 2.2e-16 60.0 0.0 1.9 1 0 0 1 1 1 1 ATP cone domain NRDD PF13597.1 CAR27083.1 - 0.01 13.9 0.0 0.016 13.2 0.0 1.2 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase LCCL PF03815.14 CAR27084.1 - 3.4e-09 36.5 0.2 6e-09 35.7 0.2 1.4 1 0 0 1 1 1 1 LCCL domain Sec6 PF06046.8 CAR27085.1 - 2e-159 531.2 12.6 2.6e-159 530.9 8.7 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec6 Tctex-1 PF03645.8 CAR27086.1 - 1.4e-07 31.2 0.0 1.8e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Tctex-1 family DUF3347 PF11827.3 CAR27086.1 - 0.013 15.5 0.0 0.015 15.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Pex19 PF04614.7 CAR27086.1 - 0.028 14.0 0.0 0.035 13.7 0.0 1.1 1 0 0 1 1 1 0 Pex19 protein family DUF202 PF02656.10 CAR27087.1 - 1.6e-13 50.6 4.0 1.6e-13 50.6 2.8 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) LHC PF00556.15 CAR27087.1 - 0.051 13.4 0.4 0.051 13.4 0.3 2.0 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit Aldedh PF00171.17 CAR27088.1 - 6.8e-182 604.9 0.2 7.7e-182 604.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CAR27088.1 - 0.00061 18.6 0.0 0.00094 18.0 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Ribosomal_S24e PF01282.14 CAR27089.1 - 3.8e-33 113.1 0.0 6.8e-33 112.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e RAMPs PF03787.10 CAR27089.1 - 0.026 14.3 0.3 1.9 8.2 0.0 2.1 2 0 0 2 2 2 0 RAMP superfamily Yos1 PF08571.5 CAR27090.1 - 1e-30 105.6 0.6 1.2e-30 105.4 0.4 1.0 1 0 0 1 1 1 1 Yos1-like Rod_cone_degen PF15201.1 CAR27090.1 - 0.11 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Progressive rod-cone degeneration Y_phosphatase PF00102.22 CAR27091.1 - 1.3e-50 171.9 0.1 2.2e-50 171.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 CAR27091.1 - 4.5e-09 36.6 0.0 1.2e-08 35.2 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.15 CAR27091.1 - 0.053 13.0 0.7 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CAR27091.1 - 0.054 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family MAM33 PF02330.11 CAR27092.1 - 5.4e-50 169.9 8.5 6.3e-50 169.7 5.9 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein Cons_hypoth95 PF03602.10 CAR27092.1 - 0.041 13.2 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PPR_2 PF13041.1 CAR27093.1 - 1.5e-16 60.0 0.1 7.7e-12 44.9 0.0 3.3 3 0 0 3 3 3 2 PPR repeat family PPR PF01535.15 CAR27093.1 - 0.088 12.8 0.2 26 5.0 0.0 4.4 6 0 0 6 6 6 0 PPR repeat Peptidase_M24 PF00557.19 CAR27095.1 - 1.8e-49 168.1 0.0 2.8e-49 167.5 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 CAR27095.1 - 3e-33 114.0 0.0 6.3e-33 113.0 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain HORMA PF02301.13 CAR27096.1 - 2.8e-52 177.2 1.7 2.8e-52 177.2 1.2 2.0 2 0 0 2 2 2 1 HORMA domain APH PF01636.18 CAR27098.1 - 6e-06 26.1 0.0 3.8e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CAR27098.1 - 0.13 11.3 0.0 7.7 5.5 0.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family SPO22 PF08631.5 CAR27099.1 - 6.5e-57 192.7 3.1 6.5e-57 192.7 2.1 3.9 5 0 0 5 5 5 2 Meiosis protein SPO22/ZIP4 like TPR_19 PF14559.1 CAR27099.1 - 0.045 14.0 0.1 0.77 10.1 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat 2-Hacid_dh_C PF02826.14 CAR27100.1 - 4.4e-52 175.8 0.0 6.5e-52 175.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CAR27100.1 - 1.5e-37 127.9 0.0 2.1e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CAR27100.1 - 7.1e-05 22.7 0.4 0.00033 20.5 0.1 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.20 CAR27100.1 - 0.00068 19.0 0.2 0.0028 17.1 0.0 2.1 2 0 0 2 2 2 1 ACT domain AdoHcyase_NAD PF00670.16 CAR27100.1 - 0.0013 18.5 0.1 0.0028 17.5 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF4367 PF14285.1 CAR27100.1 - 0.025 13.8 0.0 0.051 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4367) Acetyltransf_1 PF00583.19 CAR27100.1 - 0.06 13.3 0.0 0.17 11.9 0.0 1.8 1 1 1 2 2 2 0 Acetyltransferase (GNAT) family PC_rep PF01851.17 CAR27101.1 - 2.2e-37 125.1 23.6 0.00016 21.7 0.0 10.4 10 0 0 10 10 10 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 CAR27101.1 - 4.7e-17 62.0 4.2 3.5e-13 49.6 0.1 5.1 5 0 0 5 5 5 1 HEAT repeats HEAT_EZ PF13513.1 CAR27101.1 - 1.9e-09 37.7 1.6 0.011 16.1 0.1 4.7 3 1 1 4 4 4 2 HEAT-like repeat HEAT PF02985.17 CAR27101.1 - 5.7e-07 29.0 2.4 0.62 10.2 0.1 4.5 4 0 0 4 4 4 3 HEAT repeat RICTOR_V PF14668.1 CAR27101.1 - 0.028 14.3 0.2 0.4 10.6 0.0 3.0 3 1 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.11 CAR27101.1 - 0.079 13.4 3.2 34 5.3 0.1 4.3 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Vfa1 PF08432.5 CAR27101.1 - 0.73 9.8 14.4 1.3 8.9 10.0 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NARP1 PF12569.3 CAR27101.1 - 2.1 7.0 11.4 4.4 5.9 7.9 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 BING4CT PF08149.6 CAR27102.1 - 1.2e-37 127.2 0.1 1e-35 121.0 0.0 3.3 4 0 0 4 4 4 1 BING4CT (NUC141) domain WD40 PF00400.27 CAR27102.1 - 6.2e-07 29.0 0.0 6.5e-05 22.6 0.0 3.7 4 0 0 4 4 4 1 WD domain, G-beta repeat ATP-synt_B PF00430.13 CAR27102.1 - 1.7 8.4 6.5 0.98 9.2 0.2 2.8 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) DHO_dh PF01180.16 CAR27103.1 - 1.3e-97 326.3 0.1 1.6e-97 326.0 0.1 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 CAR27103.1 - 3.2e-05 22.9 0.0 0.05 12.4 0.1 2.5 2 1 0 2 2 2 2 FMN-dependent dehydrogenase GET2 PF08690.5 CAR27104.1 - 9.2e-64 215.5 8.9 1.8e-62 211.3 6.2 2.0 1 1 0 1 1 1 1 GET complex subunit GET2 HflK_N PF12221.3 CAR27104.1 - 1.6 8.5 3.7 0.44 10.3 0.1 1.9 2 0 0 2 2 2 0 Bacterial membrane protein N terminal Coatomer_E PF04733.9 CAR27105.1 - 2.4e-13 49.9 11.2 5e-13 48.9 7.8 1.5 1 1 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 CAR27105.1 - 6.8e-05 23.1 2.7 0.058 13.7 0.1 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CAR27105.1 - 0.016 15.7 0.4 15 6.5 0.0 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 CAR27105.1 - 0.046 14.1 7.5 34 5.1 0.0 5.4 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 CAR27105.1 - 0.13 12.7 0.1 3.9 8.1 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4167 PF13763.1 CAR27105.1 - 0.23 11.5 0.1 0.23 11.5 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4167) DUF1689 PF07954.6 CAR27106.1 - 4.9e-47 159.5 0.7 6.9e-47 159.1 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1689) tRNA-synt_2b PF00587.20 CAR27107.1 - 4.4e-43 146.8 0.4 7.5e-43 146.0 0.3 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CAR27107.1 - 6.4e-21 74.1 0.6 1.7e-20 72.7 0.4 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 CAR27107.1 - 7.7e-15 54.5 0.0 1.7e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 CAR27107.1 - 2.3e-11 43.3 0.0 4.7e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 TGS domain TcpQ PF10671.4 CAR27107.1 - 0.015 15.1 0.1 3 7.7 0.0 3.3 3 0 0 3 3 3 0 Toxin co-regulated pilus biosynthesis protein Q zf-CCHC PF00098.18 CAR27108.1 - 1.3e-11 43.8 37.0 0.00015 21.5 1.5 5.0 5 0 0 5 5 5 3 Zinc knuckle TFIIF_alpha PF05793.7 CAR27108.1 - 0.11 10.9 6.4 0.13 10.5 4.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pmp3 PF01679.12 CAR27109.1 - 4.9e-21 74.1 5.8 6.9e-21 73.6 4.0 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TM231 PF10149.4 CAR27109.1 - 0.14 11.0 0.2 0.16 10.9 0.2 1.1 1 0 0 1 1 1 0 Transmembrane protein 231 UPF0029 PF01205.14 CAR27111.1 - 8.3e-33 112.3 0.0 1.2e-32 111.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 DUF1317 PF07026.6 CAR27111.1 - 0.05 13.4 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1317) Aldo_ket_red PF00248.16 CAR27112.1 - 4.4e-42 143.8 0.0 5.5e-42 143.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FAD-oxidase_C PF02913.14 CAR27113.1 - 3.3e-59 200.1 0.0 4.5e-59 199.7 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CAR27113.1 - 2.3e-34 117.8 0.1 4e-34 117.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain HIT PF01230.18 CAR27114.1 - 4.1e-22 78.5 0.2 7e-22 77.7 0.1 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 CAR27114.1 - 1.9e-05 24.8 0.6 3.1e-05 24.1 0.4 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 CAR27114.1 - 0.0094 15.6 0.4 0.026 14.1 0.2 1.8 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 AAA PF00004.24 CAR27115.1 - 1.3e-98 326.3 0.0 2.4e-48 163.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 CAR27115.1 - 5.1e-19 68.0 1.6 1e-18 67.0 0.5 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 CAR27115.1 - 2.4e-13 50.3 0.1 5.2e-07 29.7 0.0 3.0 3 1 0 3 3 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 CAR27115.1 - 2.7e-13 49.5 0.0 1.8e-05 23.9 0.0 2.8 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 CAR27115.1 - 1.6e-12 47.2 1.6 3e-06 27.0 0.0 4.0 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CAR27115.1 - 8.3e-12 45.4 0.0 0.00052 20.0 0.0 3.6 2 2 1 3 3 3 2 AAA ATPase domain AAA_33 PF13671.1 CAR27115.1 - 2e-11 43.9 0.0 7e-06 25.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CAR27115.1 - 2.6e-11 44.4 0.4 0.0011 19.7 0.0 3.9 4 0 0 4 4 3 2 AAA domain AAA_22 PF13401.1 CAR27115.1 - 1.9e-10 41.0 3.6 0.0011 19.1 0.1 4.4 3 2 0 3 3 2 2 AAA domain CDC48_2 PF02933.12 CAR27115.1 - 9.1e-10 38.0 0.0 2.4e-09 36.6 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 TIP49 PF06068.8 CAR27115.1 - 2.7e-09 36.2 0.1 0.0012 17.6 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 CAR27115.1 - 2.1e-08 34.1 0.0 0.0038 17.1 0.0 3.0 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.12 CAR27115.1 - 9.3e-08 31.6 0.1 0.0073 15.7 0.0 2.9 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 CAR27115.1 - 2e-07 30.6 1.3 0.02 14.6 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain AAA_25 PF13481.1 CAR27115.1 - 2.6e-07 30.2 6.5 0.021 14.2 0.1 4.3 2 2 2 4 4 4 2 AAA domain RNA_helicase PF00910.17 CAR27115.1 - 2.7e-07 30.7 0.0 0.011 15.9 0.0 2.9 3 0 0 3 3 2 2 RNA helicase Mg_chelatase PF01078.16 CAR27115.1 - 2.9e-07 29.8 0.4 0.022 13.9 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 CAR27115.1 - 5.9e-07 28.7 0.0 0.013 14.6 0.0 3.0 3 0 0 3 3 3 2 Zeta toxin KaiC PF06745.8 CAR27115.1 - 1.3e-06 27.6 2.2 0.44 9.6 0.0 4.1 3 1 1 4 4 4 2 KaiC AAA_24 PF13479.1 CAR27115.1 - 5e-06 26.2 0.0 0.11 12.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 CAR27115.1 - 8.8e-06 25.6 0.0 0.0081 16.0 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_28 PF13521.1 CAR27115.1 - 1.1e-05 25.4 0.0 0.25 11.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 CAR27115.1 - 1.3e-05 24.7 0.1 0.13 11.7 0.0 3.5 3 1 0 3 3 2 2 Sigma-54 interaction domain AAA_18 PF13238.1 CAR27115.1 - 1.5e-05 25.2 0.0 0.19 12.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.12 CAR27115.1 - 2.1e-05 23.5 0.0 0.13 11.1 0.0 2.6 3 0 0 3 3 3 2 Parvovirus non-structural protein NS1 PhoH PF02562.11 CAR27115.1 - 2.3e-05 23.7 0.5 0.11 11.7 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein Sigma54_activ_2 PF14532.1 CAR27115.1 - 4e-05 23.6 0.0 0.17 11.9 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Vps4_C PF09336.5 CAR27115.1 - 5e-05 23.1 0.0 0.001 18.9 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain ABC_tran PF00005.22 CAR27115.1 - 6.3e-05 23.2 0.0 0.09 13.0 0.0 3.6 2 1 0 2 2 2 1 ABC transporter AAA_11 PF13086.1 CAR27115.1 - 6.8e-05 22.5 0.0 0.34 10.4 0.0 2.6 2 1 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 CAR27115.1 - 9e-05 22.2 0.1 0.45 10.1 0.0 3.7 2 2 1 3 3 3 1 Archaeal ATPase AAA_3 PF07726.6 CAR27115.1 - 0.00013 21.6 0.0 0.67 9.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.13 CAR27115.1 - 0.00013 21.6 0.0 0.3 10.7 0.0 3.2 4 0 0 4 4 2 1 Bacterial dnaA protein NACHT PF05729.7 CAR27115.1 - 0.00017 21.2 0.1 1.6 8.3 0.0 3.5 3 0 0 3 3 3 1 NACHT domain DUF815 PF05673.8 CAR27115.1 - 0.00025 20.0 0.0 0.35 9.7 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF815) DUF2075 PF09848.4 CAR27115.1 - 0.00049 19.1 0.0 0.69 8.8 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 CAR27115.1 - 0.00054 19.5 0.3 1.7 8.2 0.0 3.0 3 0 0 3 3 2 2 AAA domain NB-ARC PF00931.17 CAR27115.1 - 0.005 15.7 0.1 1.9 7.3 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.10 CAR27115.1 - 0.01 15.5 1.4 3.3 7.3 0.0 4.1 4 0 0 4 4 4 0 NTPase IPT PF01745.11 CAR27115.1 - 0.012 14.7 0.1 1.8 7.6 0.0 2.4 2 0 0 2 2 2 0 Isopentenyl transferase KAP_NTPase PF07693.9 CAR27115.1 - 0.018 14.0 0.2 1.8 7.5 0.0 2.9 2 2 1 3 3 3 0 KAP family P-loop domain Zot PF05707.7 CAR27115.1 - 0.023 14.1 0.3 5.5 6.4 0.1 3.6 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) SKI PF01202.17 CAR27115.1 - 0.057 13.2 0.0 4.6 7.0 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase UPF0079 PF02367.12 CAR27115.1 - 0.06 12.9 0.1 7 6.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 UFD1 PF03152.9 CAR27115.1 - 0.12 11.5 0.0 0.64 9.1 0.0 2.0 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 KTI12 PF08433.5 CAR27115.1 - 0.13 11.4 0.2 12 4.9 0.0 2.7 2 1 0 2 2 2 0 Chromatin associated protein KTI12 DEAD PF00270.24 CAR27115.1 - 0.16 11.4 0.4 26 4.2 0.0 3.3 3 1 1 4 4 3 0 DEAD/DEAH box helicase Viral_helicase1 PF01443.13 CAR27115.1 - 0.22 10.9 0.0 16 4.9 0.0 2.9 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Cyclin_N PF00134.18 CAR27116.1 - 3.9e-15 55.5 0.0 6.8e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 CAR27116.1 - 1.2e-10 42.0 0.2 2.5e-10 40.9 0.0 1.6 2 0 0 2 2 2 1 Cyclin Na_Ca_ex PF01699.19 CAR27117.1 - 4e-51 172.2 27.3 4.2e-26 91.2 2.5 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein SirB PF04247.7 CAR27117.1 - 0.4 10.4 7.6 0.14 11.9 0.6 2.9 2 1 1 3 3 3 0 Invasion gene expression up-regulator, SirB Ribosomal_60s PF00428.14 CAR27120.1 - 1.5e-22 79.7 8.3 1.8e-22 79.4 5.8 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Sigma70_ner PF04546.8 CAR27120.1 - 0.067 12.8 0.2 0.081 12.5 0.1 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region MTTB PF06253.6 CAR27120.1 - 0.097 10.4 0.0 0.11 10.2 0.0 1.1 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) IATP PF04568.7 CAR27121.1 - 1.2e-19 70.1 0.9 1.3e-19 70.0 0.6 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP HisKA PF00512.20 CAR27121.1 - 0.0025 17.7 0.2 0.0046 16.9 0.1 1.4 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Phage_GP20 PF06810.6 CAR27121.1 - 0.0045 16.4 3.1 0.0049 16.3 2.1 1.1 1 0 0 1 1 1 1 Phage minor structural protein GP20 AKNA PF12443.3 CAR27121.1 - 0.0093 15.9 0.2 0.0097 15.9 0.1 1.1 1 0 0 1 1 1 1 AT-hook-containing transcription factor Matrilin_ccoil PF10393.4 CAR27121.1 - 0.022 14.1 2.8 0.032 13.5 1.9 1.3 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin PspB PF06667.7 CAR27121.1 - 0.035 14.0 0.8 0.042 13.7 0.5 1.2 1 0 0 1 1 1 0 Phage shock protein B Fib_alpha PF08702.5 CAR27121.1 - 0.038 14.1 0.1 0.038 14.1 0.1 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DivIC PF04977.10 CAR27121.1 - 0.06 12.8 2.6 0.078 12.4 1.8 1.2 1 0 0 1 1 1 0 Septum formation initiator Bap31 PF05529.7 CAR27121.1 - 0.11 11.9 0.4 0.1 12.0 0.3 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like FlaC_arch PF05377.6 CAR27121.1 - 0.24 11.2 1.2 0.45 10.4 0.8 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF2730 PF10805.3 CAR27121.1 - 0.31 10.7 1.8 0.44 10.3 0.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) HMGL-like PF00682.14 CAR27122.1 - 3.3e-74 249.5 0.1 5.4e-74 248.8 0.1 1.3 1 0 0 1 1 1 1 HMGL-like ADP_PFK_GK PF04587.10 CAR27122.1 - 0.058 11.5 0.0 0.087 11.0 0.0 1.2 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region Cullin PF00888.17 CAR27123.1 - 3.6e-162 540.9 14.7 4.8e-162 540.5 10.2 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CAR27123.1 - 3.4e-25 87.6 0.2 1.2e-24 85.8 0.1 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain MARVEL PF01284.18 CAR27124.1 - 0.016 15.0 1.6 0.033 13.9 1.1 1.5 1 1 0 1 1 1 0 Membrane-associating domain Ada3 PF10198.4 CAR27124.1 - 0.094 12.4 0.1 0.26 11.0 0.1 1.7 1 0 0 1 1 1 0 Histone acetyltransferases subunit 3 Mit_KHE1 PF10173.4 CAR27125.1 - 8.4e-55 185.5 3.8 1.1e-54 185.1 2.7 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related ATP-synt_ab PF00006.20 CAR27126.1 - 4e-117 389.2 0.0 1e-116 387.9 0.0 1.7 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Hom_end_hint PF05203.11 CAR27126.1 - 6.7e-73 244.9 0.2 1e-72 244.3 0.2 1.3 1 0 0 1 1 1 1 Hom_end-associated Hint Hom_end PF05204.9 CAR27126.1 - 1.3e-50 169.9 0.1 5e-34 116.5 0.0 2.5 2 0 0 2 2 2 2 Homing endonuclease ATP-synt_ab_C PF00306.22 CAR27126.1 - 1.5e-19 70.5 0.0 3.7e-19 69.2 0.0 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CAR27126.1 - 3.8e-15 55.8 2.6 3.8e-15 55.8 1.8 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain LAGLIDADG_3 PF14528.1 CAR27126.1 - 0.00046 20.3 0.0 0.25 11.5 0.0 2.9 2 1 0 2 2 2 2 LAGLIDADG-like domain Hint PF01079.15 CAR27126.1 - 0.00064 18.9 0.1 0.0016 17.6 0.1 1.6 1 0 0 1 1 1 1 Hint module Hint_2 PF13403.1 CAR27126.1 - 0.003 17.5 0.0 0.0098 15.8 0.0 1.9 2 0 0 2 2 2 1 Hint domain BUD22 PF09073.5 CAR27127.1 - 0.083 11.9 15.6 0.12 11.4 10.8 1.1 1 0 0 1 1 1 0 BUD22 LRR_4 PF12799.2 CAR27127.1 - 0.46 10.1 0.1 0.46 10.1 0.0 4.5 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CAR27127.1 - 1.4 9.2 14.9 17 5.8 0.0 7.0 7 0 0 7 7 7 0 Leucine Rich repeat Ribosomal_L22 PF00237.14 CAR27129.1 - 1.7e-19 69.7 0.0 2.7e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e SHR3_chaperone PF08229.6 CAR27130.1 - 2.5e-71 238.7 0.1 2.5e-71 238.7 0.1 1.8 2 0 0 2 2 2 1 ER membrane protein SH3 Pex26 PF07163.7 CAR27130.1 - 0.0031 16.4 0.2 0.0046 15.9 0.2 1.2 1 0 0 1 1 1 1 Pex26 protein DUF445 PF04286.7 CAR27130.1 - 0.48 9.9 6.1 0.64 9.4 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Ribosomal_S3_C PF00189.15 CAR27131.1 - 1.8e-15 56.8 0.1 2.9e-15 56.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 CAR27131.1 - 3.5e-12 45.6 0.1 1.1e-11 44.0 0.1 1.8 2 0 0 2 2 2 1 KH domain Ras PF00071.17 CAR27132.1 - 7.1e-48 162.0 0.0 1e-47 161.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR27132.1 - 7.2e-14 52.3 0.0 4.9e-13 49.6 0.0 2.3 2 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 CAR27132.1 - 0.00012 21.3 0.0 0.00027 20.2 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CAR27132.1 - 0.065 12.6 0.1 0.42 10.0 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CAR27132.1 - 0.084 11.9 1.1 0.16 11.0 0.0 2.0 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region VID27 PF08553.5 CAR27132.1 - 0.19 9.9 4.6 0.26 9.4 3.2 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Drf_GBD PF06371.8 CAR27132.1 - 0.37 10.1 6.1 0.65 9.3 4.2 1.3 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain PEHE PF15275.1 CAR27132.1 - 1.1 9.7 8.1 2.4 8.6 5.6 1.6 1 0 0 1 1 1 0 PEHE domain adh_short PF00106.20 CAR27133.1 - 9.5e-09 35.3 0.0 1.6e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CAR27133.1 - 7e-07 29.0 0.0 1.2e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 KR domain WD40 PF00400.27 CAR27134.1 - 8.8e-08 31.7 2.6 0.058 13.3 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat RRM_1 PF00076.17 CAR27135.1 - 3.1e-06 26.7 0.0 6.8e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR27135.1 - 4e-06 26.7 0.0 7.8e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Glycos_transf_1 PF00534.15 CAR27135.1 - 0.046 13.1 0.9 2.8 7.3 0.2 2.5 1 1 1 2 2 2 0 Glycosyl transferases group 1 Flavodoxin_3 PF12641.2 CAR27135.1 - 0.14 11.5 0.2 0.14 11.5 0.1 1.9 3 0 0 3 3 3 0 Flavodoxin domain DUF1682 PF07946.9 CAR27135.1 - 0.75 8.5 16.6 3 6.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) SRP-alpha_N PF04086.8 CAR27135.1 - 6.3 6.0 16.8 5.8 6.2 0.8 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Pkinase PF00069.20 CAR27136.1 - 3.9e-64 216.3 0.0 5.5e-64 215.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR27136.1 - 3.7e-22 78.6 0.0 6.4e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR27136.1 - 0.094 11.6 0.0 0.21 10.5 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Ribosomal_L11_N PF03946.9 CAR27137.1 - 2e-27 94.3 0.3 3.1e-27 93.7 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 CAR27137.1 - 2.2e-26 91.7 1.0 3.6e-26 91.1 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain UCH PF00443.24 CAR27138.1 - 3.7e-54 183.6 9.5 1.6e-53 181.5 6.6 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CAR27138.1 - 8.2e-09 35.3 12.6 8.2e-09 35.3 8.7 3.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DNA_RNApol_7kD PF03604.8 CAR27138.1 - 0.028 13.8 1.1 2.5 7.6 0.0 2.7 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit DUF164 PF02591.10 CAR27138.1 - 0.075 12.8 0.1 11 5.8 0.0 2.5 2 0 0 2 2 2 0 Putative zinc ribbon domain RecR PF02132.10 CAR27138.1 - 0.2 11.1 1.0 0.35 10.3 0.0 1.9 2 0 0 2 2 2 0 RecR protein ELFV_dehydrog PF00208.16 CAR27139.1 - 3.7e-58 196.9 0.0 6.4e-58 196.1 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 CAR27139.1 - 7.2e-19 66.8 0.0 2e-13 48.7 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 CAR27139.1 - 0.046 13.2 0.0 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain JAB PF01398.16 CAR27140.1 - 2.4e-31 107.8 0.0 4.8e-31 106.8 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 CAR27140.1 - 4.7e-07 29.3 0.0 8.1e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 CAR27140.1 - 0.00092 18.7 0.0 0.0019 17.7 0.0 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0172) Tim17 PF02466.14 CAR27142.1 - 8.1e-49 164.9 6.1 9.9e-49 164.6 4.2 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DLH PF01738.13 CAR27142.1 - 0.015 14.5 0.6 0.021 14.0 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family Arm PF00514.18 CAR27144.1 - 1e-87 285.2 15.0 1.3e-13 50.1 0.1 8.9 10 0 0 10 10 10 8 Armadillo/beta-catenin-like repeat IBB PF01749.15 CAR27144.1 - 1.1e-24 86.4 5.2 2e-24 85.5 3.6 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT_2 PF13646.1 CAR27144.1 - 3.9e-24 84.7 0.1 2.5e-07 30.8 0.0 5.2 1 1 2 4 4 4 4 HEAT repeats HEAT_EZ PF13513.1 CAR27144.1 - 3.3e-19 68.7 2.7 8.8e-06 26.0 0.0 6.3 4 2 4 8 8 8 4 HEAT-like repeat HEAT PF02985.17 CAR27144.1 - 1.3e-10 40.4 0.1 0.013 15.4 0.0 6.7 7 0 0 7 7 7 3 HEAT repeat Arm_2 PF04826.8 CAR27144.1 - 5.1e-07 29.0 0.5 0.16 11.0 0.0 4.8 3 2 2 5 5 5 2 Armadillo-like Proteasom_PSMB PF10508.4 CAR27144.1 - 1.6e-05 23.4 0.3 0.00025 19.4 0.0 2.5 3 0 0 3 3 3 1 Proteasome non-ATPase 26S subunit V-ATPase_H_C PF11698.3 CAR27144.1 - 3.1e-05 23.8 0.1 0.11 12.3 0.0 4.2 4 1 0 4 4 4 1 V-ATPase subunit H Adaptin_N PF01602.15 CAR27144.1 - 5.1e-05 21.7 0.1 0.01 14.2 0.1 2.5 1 1 1 2 2 2 2 Adaptin N terminal region RICTOR_V PF14668.1 CAR27144.1 - 0.0039 17.1 5.7 4.5 7.2 0.1 5.5 3 3 4 7 7 7 1 Rapamycin-insensitive companion of mTOR, domain 5 CTNNBL PF08216.6 CAR27144.1 - 0.099 12.2 0.0 13 5.4 0.0 3.7 3 0 0 3 3 3 0 Catenin-beta-like, Arm-motif containing nuclear GATase_4 PF13230.1 CAR27146.1 - 1.8e-18 66.1 0.0 2.5e-17 62.4 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 CAR27146.1 - 5.8e-11 42.4 0.0 1.4e-10 41.2 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.16 CAR27146.1 - 6.2e-10 38.3 0.0 5.4e-08 31.9 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_7 PF13537.1 CAR27146.1 - 0.0078 15.9 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Tyr_Deacylase PF02580.11 CAR27147.1 - 1.2e-46 158.3 0.1 1.3e-46 158.1 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Chitin_synth_1 PF01644.12 CAR27148.1 - 3.6e-71 238.2 0.9 5.6e-71 237.6 0.6 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 CAR27148.1 - 2.1e-27 94.6 0.2 4.7e-27 93.4 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 CAR27148.1 - 2.8e-17 62.3 9.3 2.5e-13 49.2 2.5 2.3 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 CAR27148.1 - 1.6e-11 44.3 3.4 6.8e-11 42.2 2.3 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CAR27148.1 - 5.7e-09 36.1 0.0 1.2e-08 35.0 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CAR27148.1 - 0.016 14.9 0.0 0.18 11.4 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 Mcm10 PF09332.6 CAR27150.1 - 1.2 8.3 8.9 2.1 7.6 6.2 1.2 1 0 0 1 1 1 0 Mcm10 replication factor Phostensin_N PF13916.1 CAR27150.1 - 5.9 6.9 7.5 13 5.8 5.2 1.6 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal APC_CDC26 PF10471.4 CAR27150.1 - 9.9 6.9 18.1 39 5.0 12.5 2.1 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 SbcCD_C PF13558.1 CAR27151.1 - 0.16 11.9 0.0 0.16 11.9 0.0 2.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Ebola_NP PF05505.7 CAR27152.1 - 0.16 9.9 8.0 0.17 9.8 5.6 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein DUF2201_N PF13203.1 CAR27152.1 - 1.6 7.8 6.8 2 7.5 4.7 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Macoilin PF09726.4 CAR27152.1 - 2.8 6.1 12.4 2.7 6.1 8.6 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF3827 PF12877.2 CAR27152.1 - 5.8 4.8 13.7 8.2 4.3 9.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Ndc1_Nup PF09531.5 CAR27152.1 - 7.6 4.8 9.6 8.1 4.7 6.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RRM_1 PF00076.17 CAR27153.1 - 3.2e-18 65.1 0.0 1.9e-15 56.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR27153.1 - 3.1e-09 36.6 0.0 2.3e-07 30.6 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RR_TM4-6 PF06459.7 CAR27153.1 - 0.47 10.2 8.9 0.93 9.3 6.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF-3_zeta PF05091.7 CAR27153.1 - 0.6 8.6 12.0 0.82 8.2 8.3 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Hid1 PF12722.2 CAR27153.1 - 0.77 7.3 13.1 1.4 6.4 9.0 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FLO_LFY PF01698.11 CAR27153.1 - 1.3 7.7 8.5 2.1 7.1 5.9 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Glyco_transf_15 PF01793.11 CAR27153.1 - 5 5.9 9.6 8 5.3 6.6 1.2 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Spore_coat_CotO PF14153.1 CAR27153.1 - 5.2 6.4 19.6 11 5.4 13.6 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Pex16 PF08610.5 CAR27153.1 - 7.9 5.3 14.4 20 4.0 10.0 1.6 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Septin PF00735.13 CAR27154.1 - 1.3e-72 244.1 0.7 4.8e-65 219.3 0.4 2.3 2 0 0 2 2 2 2 Septin AAA_22 PF13401.1 CAR27154.1 - 4.3e-05 23.6 0.0 0.00021 21.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CAR27154.1 - 0.00018 21.3 0.0 0.00045 20.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CAR27154.1 - 0.00051 20.8 0.1 0.0019 19.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 CAR27154.1 - 0.00098 18.6 0.0 0.0022 17.5 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_18 PF13238.1 CAR27154.1 - 0.0029 17.9 0.7 0.015 15.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 CAR27154.1 - 0.008 16.3 0.3 0.018 15.2 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 CAR27154.1 - 0.011 15.1 0.0 0.029 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain AAA_24 PF13479.1 CAR27154.1 - 0.012 15.2 0.1 0.039 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 CAR27154.1 - 0.017 15.2 0.0 0.05 13.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 CAR27154.1 - 0.018 14.2 0.0 0.039 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Synaptobrevin PF00957.16 CAR27154.1 - 0.024 14.2 1.2 0.072 12.6 0.8 1.8 1 0 0 1 1 1 0 Synaptobrevin GTP_EFTU PF00009.22 CAR27154.1 - 0.041 13.3 0.0 0.12 11.7 0.0 1.8 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Mg_chelatase PF01078.16 CAR27154.1 - 0.046 12.8 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Dynamin_N PF00350.18 CAR27154.1 - 0.056 13.2 1.7 0.14 11.9 0.0 2.4 3 1 0 3 3 3 0 Dynamin family IstB_IS21 PF01695.12 CAR27154.1 - 0.062 12.7 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.1 CAR27154.1 - 0.069 13.1 0.2 0.85 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 CAR27154.1 - 0.072 13.0 3.5 0.079 12.9 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.9 CAR27154.1 - 0.088 12.5 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 CAR27154.1 - 0.16 11.5 0.0 0.37 10.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF1799 PF08809.6 CAR27155.1 - 0.04 13.7 0.0 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 Phage related hypothetical protein (DUF1799) FadA PF09403.5 CAR27155.1 - 0.12 12.3 1.2 0.84 9.6 0.1 2.4 2 0 0 2 2 2 0 Adhesion protein FadA TMF_DNA_bd PF12329.3 CAR27155.1 - 0.97 9.2 6.4 1.5 8.6 0.5 3.3 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding YjeF_N PF03853.10 CAR27156.1 - 7.7e-35 119.9 0.0 9.1e-35 119.7 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus SMK-1 PF04802.10 CAR27157.1 - 1.1e-63 214.3 6.0 2.9e-62 209.6 2.1 2.5 2 0 0 2 2 2 2 Component of IIS longevity pathway SMK-1 Ric8 PF10165.4 CAR27157.1 - 0.017 13.9 0.0 0.2 10.4 0.0 2.1 2 0 0 2 2 2 0 Guanine nucleotide exchange factor synembryn adh_short_C2 PF13561.1 CAR27158.1 - 3.1e-28 99.1 0.0 3.8e-28 98.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CAR27158.1 - 3.6e-23 82.3 1.4 5.4e-23 81.7 1.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CAR27158.1 - 3.5e-10 39.8 0.2 5.7e-10 39.1 0.1 1.2 1 0 0 1 1 1 1 KR domain ArfGap PF01412.13 CAR27159.1 - 2.6e-33 114.2 0.0 7.5e-33 112.7 0.0 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Rtt106 PF08512.7 CAR27160.1 - 1.5e-29 101.8 1.1 2.9e-29 100.9 0.7 1.5 1 0 0 1 1 1 1 Histone chaperone Rttp106-like RIO1 PF01163.17 CAR27161.1 - 6.5e-41 139.7 0.1 1.1e-40 139.0 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 CAR27161.1 - 3.3e-31 107.1 0.1 1.3e-30 105.2 0.0 2.0 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.18 CAR27161.1 - 1.4e-07 31.4 0.2 0.0037 17.0 0.0 2.9 1 1 2 3 3 3 2 Phosphotransferase enzyme family Pkinase PF00069.20 CAR27161.1 - 0.0075 15.4 0.1 0.015 14.4 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 CAR27161.1 - 0.076 12.0 0.2 1.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Nop14 PF04147.7 CAR27161.1 - 3.7 5.3 10.9 4.8 4.9 7.5 1.1 1 0 0 1 1 1 0 Nop14-like family E6 PF00518.12 CAR27162.1 - 4.1e-05 23.8 1.3 6.2e-05 23.2 0.9 1.3 1 0 0 1 1 1 1 Early Protein (E6) Cytochrom_NNT PF03264.9 CAR27162.1 - 0.0024 17.3 2.2 0.004 16.5 1.5 1.3 1 0 0 1 1 1 1 NapC/NirT cytochrome c family, N-terminal region Cytochrome_C554 PF13435.1 CAR27162.1 - 0.0038 17.2 0.3 0.011 15.8 0.1 1.7 2 0 0 2 2 2 1 Cytochrome c554 and c-prime Cytochrome_C7 PF14522.1 CAR27162.1 - 0.0066 16.0 0.4 0.0066 16.0 0.3 1.7 2 0 0 2 2 2 1 Cytochrome c7 Cytochrom_c3_2 PF14537.1 CAR27162.1 - 0.012 15.9 3.4 0.037 14.3 2.4 1.9 1 1 0 1 1 1 0 Cytochrome c3 Paired_CXXCH_1 PF09699.5 CAR27162.1 - 0.014 14.9 1.2 0.89 9.1 0.0 2.5 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) zf-CHY PF05495.7 CAR27162.1 - 0.032 14.3 1.7 0.08 13.1 1.2 1.6 1 0 0 1 1 1 0 CHY zinc finger zf-dskA_traR PF01258.12 CAR27162.1 - 0.28 10.9 3.5 2.5 7.9 0.4 2.3 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Cytochrom_CIII PF02085.11 CAR27162.1 - 0.28 11.3 5.4 0.12 12.4 1.4 2.0 2 1 0 2 2 2 0 Class III cytochrome C family DUF3365 PF11845.3 CAR27162.1 - 0.37 10.6 3.2 0.6 9.9 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3365) Rick_17kDa_Anti PF05433.10 CAR27163.1 - 0.00011 21.8 13.3 0.00011 21.8 9.3 3.4 2 1 1 3 3 3 1 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.1 CAR27163.1 - 0.002 17.8 0.7 0.002 17.8 0.5 2.4 3 0 0 3 3 3 1 Glycine-zipper containing OmpA-like membrane domain VIT1 PF01988.14 CAR27163.1 - 0.12 11.8 0.7 0.26 10.7 0.4 1.5 1 1 0 1 1 1 0 VIT family Ribonuclease_T2 PF00445.13 CAR27164.1 - 6.8e-25 87.7 0.0 9.3e-25 87.3 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Hom_end_hint PF05203.11 CAR27165.1 - 7.6e-49 166.3 0.0 9e-49 166.1 0.0 1.0 1 0 0 1 1 1 1 Hom_end-associated Hint Hom_end PF05204.9 CAR27165.1 - 1.4e-45 153.7 0.0 3.9e-37 126.5 0.0 2.6 2 0 0 2 2 2 2 Homing endonuclease LAGLIDADG_3 PF14528.1 CAR27165.1 - 4e-07 30.1 0.0 8e-05 22.7 0.0 2.5 2 0 0 2 2 2 2 LAGLIDADG-like domain DUF1794 PF08768.6 CAR27165.1 - 0.14 11.9 0.4 0.39 10.5 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1794) HSP70 PF00012.15 CAR27166.1 - 3.2e-233 775.0 9.5 3.5e-233 774.9 6.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CAR27166.1 - 1.8e-17 62.9 0.4 6.3e-16 57.8 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DUF2603 PF10788.4 CAR27166.1 - 0.049 13.3 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2603) KH_1 PF00013.24 CAR27167.1 - 7.3e-08 31.9 0.0 1.8e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 CAR27167.1 - 1.2e-05 24.7 0.3 3.1e-05 23.5 0.2 1.8 1 0 0 1 1 1 1 KH domain KH_2 PF07650.12 CAR27167.1 - 0.0016 17.9 0.0 0.0073 15.8 0.1 2.1 2 0 0 2 2 2 1 KH domain DUF863 PF05904.6 CAR27167.1 - 0.018 13.3 0.0 0.026 12.8 0.0 1.3 1 1 0 1 1 1 0 Plant protein of unknown function (DUF863) IL2 PF00715.12 CAR27167.1 - 0.16 11.6 2.1 0.28 10.9 0.1 2.2 2 1 0 2 2 2 0 Interleukin 2 Y_phosphatase PF00102.22 CAR27168.1 - 4.9e-56 189.6 1.7 1.5e-54 184.7 1.2 2.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 CAR27168.1 - 0.00012 21.6 0.0 0.00021 20.8 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CAR27168.1 - 0.0049 17.1 0.0 0.0097 16.1 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 CAR27168.1 - 0.0054 16.7 0.0 0.025 14.6 0.0 2.0 2 0 0 2 2 2 1 Inositol hexakisphosphate DUF2421 PF10334.4 CAR27169.1 - 8e-07 28.9 0.0 1.6e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) DUF2422 PF10337.4 CAR27169.1 - 1.6e-06 27.1 1.1 1.6e-06 27.1 0.8 3.2 3 1 0 3 3 3 2 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 CAR27169.1 - 7.1e-06 25.9 23.5 1.5e-05 24.9 6.3 2.5 2 0 0 2 2 2 2 Fusaric acid resistance protein-like DUF2379 PF09543.5 CAR27169.1 - 0.0028 17.5 0.1 13 5.7 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF2379) ALMT PF11744.3 CAR27169.1 - 0.021 13.5 1.9 0.14 10.7 0.0 2.6 2 1 0 2 2 2 0 Aluminium activated malate transporter FUSC PF04632.7 CAR27169.1 - 1.1 7.6 4.0 8.2 4.7 0.0 2.7 2 1 1 3 3 3 0 Fusaric acid resistance protein family DUF2697 PF10906.3 CAR27170.1 - 2.5e-28 97.8 0.1 3e-28 97.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2697) VID27 PF08553.5 CAR27171.1 - 1.5e-289 962.7 15.2 1.8e-289 962.5 10.5 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein EBV-NA3 PF05009.7 CAR27171.1 - 0.0063 15.8 7.6 0.19 10.9 0.5 2.3 2 0 0 2 2 2 2 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Neugrin PF06413.6 CAR27172.1 - 9e-07 28.9 1.7 9e-07 28.9 1.2 1.8 1 1 0 1 1 1 1 Neugrin Sigma70_r4 PF04545.11 CAR27172.1 - 0.014 14.6 0.1 0.033 13.5 0.1 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 Integrase_Zn PF02022.14 CAR27172.1 - 0.025 14.0 0.6 0.068 12.6 0.0 2.0 2 0 0 2 2 2 0 Integrase Zinc binding domain Tmemb_161AB PF10268.4 CAR27172.1 - 0.065 11.7 0.0 0.096 11.1 0.0 1.2 1 0 0 1 1 1 0 Predicted transmembrane protein 161AB DUF349 PF03993.7 CAR27172.1 - 0.14 12.3 0.4 0.14 12.3 0.3 2.3 3 1 0 3 3 3 0 Domain of Unknown Function (DUF349) LIM_bind PF01803.11 CAR27174.1 - 2.8e-14 52.8 2.1 6.2e-14 51.6 1.5 1.6 1 1 0 1 1 1 1 LIM-domain binding protein PAPA-1 PF04795.7 CAR27175.1 - 4.3e-13 49.7 11.4 4.3e-13 49.7 7.9 2.9 2 2 0 2 2 2 1 PAPA-1-like conserved region RabGAP-TBC PF00566.13 CAR27176.1 - 2.3e-33 115.4 18.2 4.2e-31 108.0 6.7 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DUF3548 PF12068.3 CAR27176.1 - 8.8e-06 25.1 0.1 0.02 14.1 0.0 2.5 1 1 0 2 2 2 2 Domain of unknown function (DUF3548) Rap1-DNA-bind PF09197.5 CAR27177.1 - 9.4e-44 148.2 12.7 1.9e-41 140.8 0.1 4.1 3 1 0 3 3 3 2 Rap1, DNA-binding Rap1_C PF11626.3 CAR27177.1 - 2.4e-23 81.8 0.0 3.1e-22 78.2 0.0 2.8 3 0 0 3 3 3 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 CAR27177.1 - 1.6e-08 34.2 0.2 9.5e-05 22.1 0.0 2.9 2 0 0 2 2 2 2 Rap1 Myb domain Myb_DNA-binding PF00249.26 CAR27177.1 - 5.2e-08 32.8 0.0 2e-06 27.7 0.0 3.0 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CAR27177.1 - 0.0024 17.9 0.3 0.65 10.1 0.0 3.5 3 0 0 3 3 3 1 Myb-like DNA-binding domain BRCT PF00533.21 CAR27177.1 - 0.02 15.0 0.0 0.14 12.3 0.0 2.5 1 1 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain FAD_binding_2 PF00890.19 CAR27178.1 - 2e-122 409.0 2.3 2.7e-122 408.6 1.6 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 CAR27178.1 - 1.4e-45 154.2 2.4 2.2e-45 153.6 1.7 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 CAR27178.1 - 5.5e-07 29.6 0.1 0.00029 20.7 0.1 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CAR27178.1 - 5.4e-05 22.2 3.2 0.00058 18.8 2.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 CAR27178.1 - 0.00042 19.2 5.7 0.0058 15.5 1.3 2.6 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_3 PF01494.14 CAR27178.1 - 0.00051 19.2 3.4 0.0049 15.9 0.1 2.8 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.12 CAR27178.1 - 0.00053 19.1 0.1 0.008 15.3 0.0 2.4 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 CAR27178.1 - 0.023 13.1 0.1 0.15 10.5 0.0 2.4 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_8 PF13450.1 CAR27178.1 - 0.084 12.9 1.1 0.84 9.7 0.3 2.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Metallophos PF00149.23 CAR27179.1 - 4.1e-13 49.1 2.8 6.7e-13 48.4 2.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DBR1 PF05011.8 CAR27179.1 - 1.7e-10 40.9 0.1 2.9e-10 40.1 0.1 1.3 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain NAD_binding_1 PF00175.16 CAR27180.1 - 3.8e-25 88.5 0.0 5.8e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CAR27180.1 - 5.2e-25 87.4 0.0 8e-25 86.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 CAR27180.1 - 1.5e-07 31.4 0.0 0.00013 21.8 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Carb_kinase PF01256.12 CAR27181.1 - 1.8e-66 223.8 0.0 2.9e-66 223.2 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 CAR27181.1 - 0.016 14.4 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase His_Phos_1 PF00300.17 CAR27182.1 - 8.1e-43 146.2 0.0 1.1e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RabGAP-TBC PF00566.13 CAR27183.1 - 1.1e-19 70.7 0.3 1.6e-19 70.2 0.2 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain LRR_6 PF13516.1 CAR27184.1 - 0.0032 17.3 2.4 9.9 6.5 0.0 5.0 5 0 0 5 5 5 2 Leucine Rich repeat Nsp1_C PF05064.8 CAR27185.1 - 3.8e-37 126.5 4.3 3.8e-37 126.5 3.0 2.0 1 1 1 2 2 2 1 Nsp1-like C-terminal region Laminin_II PF06009.7 CAR27185.1 - 0.027 14.2 11.3 2.6 7.7 5.1 2.9 1 1 2 3 3 3 0 Laminin Domain II Nucleoporin_FG PF13634.1 CAR27185.1 - 0.28 11.4 225.5 2.4 8.4 18.6 7.9 1 1 4 5 5 5 0 Nucleoporin FG repeat region DUF87 PF01935.12 CAR27185.1 - 1.1 9.0 6.3 2.8 7.7 4.4 1.6 1 1 0 1 1 1 0 Domain of unknown function DUF87 SHIPPO-rpt PF07004.7 CAR27185.1 - 1.5 9.8 74.0 9.7 7.3 0.4 18.8 6 5 4 10 10 10 0 Sperm-tail PG-rich repeat DUF3414 PF11894.3 CAR27186.1 - 0 1458.8 57.4 0 1458.6 39.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) DPM2 PF07297.7 CAR27187.1 - 2.7e-10 40.3 1.9 3.2e-10 40.1 1.3 1.1 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 CAR27187.1 - 2e-05 24.2 3.0 2.1e-05 24.1 2.1 1.1 1 0 0 1 1 1 1 PIG-P Peptidase_M50 PF02163.17 CAR27187.1 - 0.26 10.2 1.6 0.32 9.9 1.1 1.1 1 0 0 1 1 1 0 Peptidase family M50 SRPRB PF09439.5 CAR27188.1 - 1.6e-62 209.9 0.0 2.2e-62 209.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 CAR27188.1 - 5.8e-07 28.9 0.0 8.5e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CAR27188.1 - 7.5e-06 25.2 0.0 1.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CAR27188.1 - 1.1e-05 25.4 0.0 1.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 CAR27188.1 - 0.043 13.3 0.1 0.095 12.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 CAR27188.1 - 0.044 14.1 2.3 0.13 12.5 1.6 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CAR27188.1 - 0.15 12.0 0.1 3 7.7 0.0 2.4 1 1 1 2 2 2 0 AAA ATPase domain Rsm22 PF09243.5 CAR27189.1 - 1.5e-31 109.4 0.8 5e-12 45.4 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.1 CAR27189.1 - 2.7e-06 27.1 0.0 5.4e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR27189.1 - 0.027 15.0 0.0 0.11 13.0 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain DUF1284 PF06935.6 CAR27189.1 - 0.92 9.7 3.4 1.6 8.9 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1284) Ribosomal_S27e PF01667.12 CAR27190.1 - 2.1e-30 103.9 2.7 2.9e-30 103.5 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 CAR27190.1 - 2.8e-05 23.9 0.7 3.4e-05 23.6 0.5 1.1 1 0 0 1 1 1 1 IBR domain TF_Zn_Ribbon PF08271.7 CAR27190.1 - 0.051 12.9 3.8 0.074 12.3 2.6 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding zinc_ribbon_5 PF13719.1 CAR27190.1 - 0.13 11.8 1.3 6.2 6.5 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CAR27190.1 - 0.14 11.8 1.3 6.3 6.5 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Myosin_head PF00063.16 CAR27191.1 - 2.2e-246 819.2 11.5 2.2e-246 819.2 8.0 4.7 5 2 1 6 6 6 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 CAR27191.1 - 0.0013 16.5 48.6 0.0013 16.5 33.7 6.1 1 1 3 4 4 4 1 Myosin tail AAA_22 PF13401.1 CAR27191.1 - 0.4 10.8 0.0 0.4 10.8 0.0 4.9 5 1 1 6 6 6 0 AAA domain Reo_sigmaC PF04582.7 CAR27191.1 - 2.3 7.2 77.2 0.24 10.5 7.2 9.0 3 2 7 10 10 10 0 Reovirus sigma C capsid protein Peptidase_M16 PF00675.15 CAR27192.1 - 1.4e-45 154.6 0.0 8.9e-44 148.8 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CAR27192.1 - 1.1e-43 149.0 0.0 3.1e-43 147.6 0.0 1.7 2 0 0 2 2 2 1 Peptidase M16 inactive domain GST_N PF02798.15 CAR27192.1 - 0.11 12.6 0.1 1.5 9.0 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain XPG_N PF00752.12 CAR27193.1 - 7.3e-29 100.0 0.0 1.4e-28 99.1 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 CAR27193.1 - 1.9e-22 79.1 0.0 4e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 XPG I-region HHH_2 PF12826.2 CAR27193.1 - 0.00023 20.9 0.0 0.013 15.3 0.0 2.8 3 0 0 3 3 3 1 Helix-hairpin-helix motif 5_3_exonuc PF01367.15 CAR27193.1 - 0.00043 20.4 0.0 0.0011 19.2 0.0 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold XPG_I_2 PF12813.2 CAR27193.1 - 0.00099 18.6 0.0 0.0029 17.1 0.0 1.8 1 0 0 1 1 1 1 XPG domain containing Ank_2 PF12796.2 CAR27194.1 - 2.2e-37 127.2 0.0 4.6e-19 68.5 0.0 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 CAR27194.1 - 8.5e-28 94.7 0.1 2.7e-07 30.0 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat zf-DHHC PF01529.15 CAR27194.1 - 3.5e-26 91.6 1.2 3.5e-26 91.6 0.9 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_5 PF13857.1 CAR27194.1 - 5.1e-23 80.5 0.6 2.3e-06 27.6 0.1 5.1 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 CAR27194.1 - 8.3e-22 77.1 0.3 4.4e-08 33.4 0.1 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CAR27194.1 - 3.5e-21 73.1 0.0 7.9e-05 22.5 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat UNC45-central PF11701.3 CAR27195.1 - 7.2e-26 90.7 5.0 7.2e-26 90.7 3.5 3.5 4 1 0 4 4 4 1 Myosin-binding striated muscle assembly central Pex2_Pex12 PF04757.9 CAR27196.1 - 5.6e-36 124.0 4.4 1.4e-35 122.8 3.1 1.5 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 CAR27196.1 - 3.9e-08 33.1 17.6 6.7e-08 32.4 12.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CAR27196.1 - 9.3e-08 31.7 16.4 1.6e-07 31.0 11.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CAR27196.1 - 1.4e-06 27.9 17.0 2.1e-06 27.3 11.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CAR27196.1 - 1.7e-06 27.6 16.7 2.8e-06 26.8 11.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAR27196.1 - 4.6e-05 23.0 13.6 8.9e-05 22.1 9.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 CAR27196.1 - 7.4e-05 22.7 10.0 0.00016 21.6 6.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 CAR27196.1 - 0.004 17.0 17.2 0.0079 16.0 11.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING PP2C_C PF07830.8 CAR27196.1 - 0.098 12.7 0.0 0.35 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain zf-RING_UBOX PF13445.1 CAR27196.1 - 0.22 11.2 11.8 0.11 12.1 6.0 2.2 2 1 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_3 PF13920.1 CAR27197.1 - 8.9e-09 34.8 8.8 8.9e-09 34.8 6.1 3.9 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CAR27197.1 - 6.5 6.4 29.4 0.02 14.5 7.7 3.9 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Syntaxin_2 PF14523.1 CAR27198.1 - 5.5e-20 71.3 7.3 5.5e-20 71.3 5.0 2.4 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 CAR27198.1 - 2.2e-18 65.6 3.9 2.2e-18 65.6 2.7 3.1 2 1 0 2 2 2 1 SNARE domain DUF1212 PF06738.7 CAR27198.1 - 0.0056 16.1 0.1 0.0056 16.1 0.1 2.1 2 1 1 3 3 3 1 Protein of unknown function (DUF1212) AIF-MLS PF14962.1 CAR27198.1 - 0.14 11.8 2.4 0.2 11.3 1.7 1.3 1 0 0 1 1 1 0 Mitochondria Localisation Sequence Syntaxin PF00804.20 CAR27198.1 - 0.17 12.0 0.2 0.17 12.0 0.2 3.4 2 1 1 3 3 3 0 Syntaxin DUF912 PF06024.7 CAR27198.1 - 3.7 7.6 6.3 0.55 10.3 0.2 2.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3675 PF12428.3 CAR27198.1 - 6.4 7.0 6.3 1.6 8.9 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3675) BLOC1_2 PF10046.4 CAR27198.1 - 6.5 6.9 16.6 0.52 10.4 0.7 3.6 3 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 WD40 PF00400.27 CAR27199.1 - 6e-58 190.8 23.0 4.6e-12 45.3 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 CAR27199.1 - 0.0086 14.9 7.7 0.14 10.9 0.9 3.0 2 1 1 3 3 3 2 Coatomer WD associated region CRT10 PF08728.5 CAR27199.1 - 0.031 12.2 1.0 0.18 9.7 0.0 2.4 2 1 0 2 2 2 0 CRT10 FAD_binding_6 PF00970.19 CAR27200.1 - 3.9e-08 33.3 0.0 2.4e-06 27.6 0.0 2.8 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain tRNA-synt_1b PF00579.20 CAR27201.1 - 7.5e-78 261.5 0.2 9.7e-78 261.2 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Hira PF07569.6 CAR27202.1 - 1.6e-85 285.8 0.1 1.6e-85 285.8 0.0 3.0 3 1 0 3 3 3 1 TUP1-like enhancer of split WD40 PF00400.27 CAR27202.1 - 9.9e-05 22.0 3.7 1.4 8.9 0.0 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat CK_II_beta PF01214.13 CAR27203.1 - 5.8e-72 241.0 0.0 7e-72 240.7 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit E1-E2_ATPase PF00122.15 CAR27204.1 - 5.7e-46 156.3 0.1 5.7e-46 156.3 0.0 2.1 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 CAR27204.1 - 1e-33 117.6 0.0 1.8e-33 116.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 CAR27204.1 - 1.2e-30 105.4 11.3 5.3e-15 55.2 0.9 2.6 2 0 0 2 2 2 2 Heavy-metal-associated domain HAD PF12710.2 CAR27204.1 - 3.2e-14 53.5 0.1 6.7e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CAR27204.1 - 1.2e-06 28.2 0.1 0.059 12.9 0.0 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF211 PF02680.9 CAR27204.1 - 0.076 12.8 0.5 0.32 10.8 0.3 2.1 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 Lactamase_B PF00753.22 CAR27205.1 - 2.5e-19 69.7 0.0 3.4e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CAR27205.1 - 0.0002 20.9 0.1 0.00037 20.0 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain CUE PF02845.11 CAR27206.1 - 9.7e-10 37.7 0.0 1.6e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 CUE domain SDA1 PF05285.7 CAR27207.1 - 2.2e-97 326.2 41.9 2.2e-97 326.2 29.1 2.5 3 0 0 3 3 3 1 SDA1 NUC130_3NT PF08158.7 CAR27207.1 - 1.2e-21 76.6 2.3 1.5e-21 76.3 0.2 2.2 2 0 0 2 2 2 1 NUC130/3NT domain Trans_reg_C PF00486.23 CAR27207.1 - 0.011 15.5 3.5 0.11 12.4 0.1 3.4 4 0 0 4 4 4 0 Transcriptional regulatory protein, C terminal TFIIB PF00382.14 CAR27208.1 - 9.8e-56 185.4 1.2 3.1e-28 97.3 0.2 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 CAR27208.1 - 3.6e-30 104.0 2.6 3.6e-30 104.0 1.8 2.7 2 0 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 CAR27208.1 - 3.4e-11 42.2 2.6 6.9e-11 41.2 1.8 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 CAR27208.1 - 7.1e-06 25.5 0.5 0.013 15.0 0.1 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain A2L_zn_ribbon PF08792.5 CAR27208.1 - 0.4 10.1 3.0 0.87 9.1 2.1 1.6 1 0 0 1 1 1 0 A2L zinc ribbon domain TLP-20 PF06088.6 CAR27208.1 - 2.9 7.5 9.6 0.064 12.9 0.9 2.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CPDase PF07823.6 CAR27209.1 - 1.8e-70 236.4 0.2 2.1e-70 236.2 0.2 1.0 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 CAR27209.1 - 1.5e-05 24.7 0.0 0.0002 21.1 0.0 2.1 1 1 1 2 2 2 2 2'-5' RNA ligase superfamily LigT_PEase PF02834.11 CAR27209.1 - 0.095 12.6 0.0 2.7 8.0 0.0 2.3 2 0 0 2 2 2 0 LigT like Phosphoesterase Glucosamine_iso PF01182.15 CAR27210.1 - 3.3e-51 173.8 0.0 3.8e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase HSF_DNA-bind PF00447.12 CAR27211.1 - 5.4e-25 87.5 0.0 8e-25 87.0 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Dna2 PF08696.6 CAR27212.1 - 2.3e-59 200.2 2.5 3.4e-59 199.6 0.1 2.3 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_12 PF13087.1 CAR27212.1 - 7.9e-49 165.7 0.2 1.9e-48 164.4 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CAR27212.1 - 3.9e-36 124.8 4.4 1e-17 64.5 0.0 3.3 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.1 CAR27212.1 - 2.2e-12 46.9 0.0 5.1e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.2 CAR27212.1 - 1e-07 31.6 0.0 1.9e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.13 CAR27212.1 - 2.2e-07 30.6 0.4 0.1 12.0 0.0 3.8 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 CAR27212.1 - 5.6e-07 29.2 0.1 1.2e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain DUF911 PF06023.7 CAR27212.1 - 0.00019 20.7 0.0 0.00047 19.4 0.0 1.6 1 0 0 1 1 1 1 Archaeal protein of unknown function (DUF911) Cas_Cas4 PF01930.12 CAR27212.1 - 0.00095 19.1 0.0 0.003 17.4 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function DUF83 MobB PF03205.9 CAR27212.1 - 0.0011 18.6 0.1 0.0026 17.4 0.1 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 CAR27212.1 - 0.0013 18.1 0.1 0.003 17.0 0.1 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.1 CAR27212.1 - 0.0016 18.4 0.0 0.0071 16.3 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain CbiA PF01656.18 CAR27212.1 - 0.0037 16.6 0.0 0.016 14.6 0.0 2.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_10 PF12846.2 CAR27212.1 - 0.0041 16.6 0.3 0.025 14.0 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain AAA_25 PF13481.1 CAR27212.1 - 0.0086 15.4 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 CAR27212.1 - 0.0093 15.4 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 CAR27212.1 - 0.016 14.7 0.1 0.053 13.0 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Helicase_RecD PF05127.9 CAR27212.1 - 0.018 14.7 0.0 0.068 12.8 0.0 2.0 1 1 0 1 1 1 0 Helicase ArgK PF03308.11 CAR27212.1 - 0.018 13.7 0.0 0.033 12.9 0.0 1.3 1 0 0 1 1 1 0 ArgK protein NTPase_1 PF03266.10 CAR27212.1 - 0.021 14.5 0.1 0.051 13.2 0.1 1.5 1 0 0 1 1 1 0 NTPase T2SE PF00437.15 CAR27212.1 - 0.037 12.9 0.0 0.069 12.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.1 CAR27212.1 - 0.04 13.7 0.0 0.17 11.7 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 CAR27212.1 - 0.049 13.1 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 CAR27212.1 - 0.071 13.9 1.8 1.3 9.8 0.0 3.4 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.13 CAR27212.1 - 0.13 11.7 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_18 PF13238.1 CAR27212.1 - 0.71 10.1 0.0 0.71 10.1 0.0 3.9 4 0 0 4 4 3 0 AAA domain DUF240 PF03086.9 CAR27213.1 - 0.041 13.5 0.2 0.072 12.7 0.2 1.4 1 0 0 1 1 1 0 MG032/MG096/MG288 family 2 CAML PF14963.1 CAR27213.1 - 6.4 6.0 7.8 0.66 9.2 2.5 1.5 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand PROCN PF08083.6 CAR27214.1 - 1.9e-214 711.7 12.7 3e-214 711.0 8.8 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 CAR27214.1 - 5.2e-122 405.5 0.7 1.1e-121 404.4 0.5 1.6 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 CAR27214.1 - 8.5e-88 291.7 0.5 1.9e-87 290.5 0.4 1.7 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 CAR27214.1 - 8.7e-77 255.9 2.5 2.1e-76 254.7 1.7 1.7 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 CAR27214.1 - 2.6e-63 211.6 0.0 5.2e-63 210.6 0.0 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 CAR27214.1 - 7.3e-46 154.9 0.0 1.5e-45 153.9 0.0 1.6 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.4 CAR27214.1 - 2.9e-43 145.6 0.5 7.5e-43 144.3 0.4 1.7 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.16 CAR27214.1 - 0.076 12.7 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease APC8 PF04049.8 CAR27215.1 - 3.7e-35 120.7 0.2 7.6e-35 119.7 0.1 1.5 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 CAR27215.1 - 5e-19 67.0 27.1 3.5e-06 26.3 0.5 7.7 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.1 CAR27215.1 - 4.4e-17 61.4 27.2 7.1e-08 31.9 0.2 5.9 3 1 2 6 6 6 3 TPR repeat TPR_8 PF13181.1 CAR27215.1 - 9.9e-17 59.4 21.3 0.0025 17.4 0.2 8.8 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 CAR27215.1 - 1.9e-16 58.5 28.6 5.7e-06 25.8 0.7 8.7 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.1 CAR27215.1 - 1.7e-13 50.3 18.8 2e-05 24.4 1.8 5.7 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 CAR27215.1 - 7e-11 41.7 8.3 0.0021 18.5 0.7 5.7 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 CAR27215.1 - 2.8e-09 36.0 8.3 2.8e-05 23.5 0.2 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 CAR27215.1 - 6.1e-09 36.3 8.3 0.00056 20.5 0.0 4.7 4 1 1 5 5 4 3 Tetratricopeptide repeat ChAPs PF09295.5 CAR27215.1 - 2.2e-05 23.4 0.3 0.0062 15.3 0.0 2.1 1 1 1 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.1 CAR27215.1 - 0.00033 20.9 8.9 0.091 13.1 0.3 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 CAR27215.1 - 0.00036 20.5 18.6 0.041 14.0 0.0 6.2 7 0 0 7 7 5 3 Tetratricopeptide repeat BTAD PF03704.12 CAR27215.1 - 0.00042 20.6 1.1 0.00098 19.4 0.4 1.8 1 1 0 1 1 1 1 Bacterial transcriptional activator domain RPN7 PF10602.4 CAR27215.1 - 0.00048 19.5 2.0 0.002 17.5 0.9 2.4 3 1 0 3 3 3 1 26S proteasome subunit RPN7 TPR_10 PF13374.1 CAR27215.1 - 0.00061 19.6 6.6 1.4 8.9 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 CAR27215.1 - 0.0013 18.5 3.7 0.043 13.6 0.9 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.1 CAR27215.1 - 0.0052 15.8 8.8 0.039 13.0 0.3 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 CAR27215.1 - 0.014 15.5 27.7 1.1 9.5 0.2 5.6 2 1 4 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 CAR27215.1 - 0.11 12.3 5.1 7.7 6.4 0.2 3.4 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain DUF2106 PF09879.4 CAR27215.1 - 0.12 11.7 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2106) NSF PF02071.15 CAR27215.1 - 2.1 9.2 6.7 38 5.5 0.1 4.8 4 0 0 4 4 4 0 Aromatic-di-Alanine (AdAR) repeat THP2 PF09432.5 CAR27216.1 - 3.1e-51 172.6 4.9 3.1e-51 172.6 3.4 1.7 2 0 0 2 2 2 1 Tho complex subunit THP2 DUF2310 PF10071.4 CAR27216.1 - 0.021 13.8 4.9 0.034 13.1 0.2 2.2 2 0 0 2 2 2 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) Phage_Mu_Gam PF07352.7 CAR27216.1 - 0.54 9.7 7.6 1.2 8.6 1.2 2.4 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein Syntaxin PF00804.20 CAR27216.1 - 0.72 10.0 9.1 0.49 10.5 0.5 3.3 2 1 0 2 2 2 0 Syntaxin DUF2205 PF10224.4 CAR27216.1 - 3 7.4 9.6 1 8.9 0.5 3.3 3 0 0 3 3 3 0 Predicted coiled-coil protein (DUF2205) RasGEF_N_2 PF14663.1 CAR27216.1 - 3.4 7.6 8.3 0.53 10.2 0.8 2.8 2 2 1 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Cid2 PF09774.4 CAR27216.1 - 3.5 7.7 7.3 3.1 7.8 1.8 2.2 2 0 0 2 2 2 0 Caffeine-induced death protein 2 GTP1_OBG PF01018.17 CAR27217.1 - 2.3e-32 111.7 3.0 7.7e-24 84.1 1.0 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 CAR27217.1 - 4.8e-21 74.8 0.0 9.1e-21 73.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CAR27217.1 - 7.8e-12 44.7 0.0 1.2e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.16 CAR27217.1 - 2e-09 36.9 0.0 5.2e-09 35.5 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 CAR27217.1 - 1.5e-05 25.4 0.0 3.2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 CAR27217.1 - 3.2e-05 23.4 0.1 0.0024 17.3 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Ras PF00071.17 CAR27217.1 - 0.00077 18.8 0.0 0.0021 17.4 0.0 1.7 2 0 0 2 2 2 1 Ras family SRPRB PF09439.5 CAR27217.1 - 0.0049 16.1 0.0 0.0092 15.2 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 CAR27217.1 - 0.011 15.6 0.2 6.7 6.4 0.0 2.7 2 1 1 3 3 3 0 Dynamin family ArgK PF03308.11 CAR27217.1 - 0.074 11.8 0.1 0.75 8.5 0.0 2.1 2 0 0 2 2 2 0 ArgK protein DEAD PF00270.24 CAR27218.1 - 1.5e-37 128.6 0.0 1.9e-36 125.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR27218.1 - 8.2e-27 92.8 0.4 2e-26 91.6 0.1 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAR27218.1 - 0.015 15.0 0.4 0.054 13.3 0.0 2.1 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DUF2702 PF10863.3 CAR27219.1 - 1.8e-38 131.4 6.3 1.8e-38 131.4 4.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2702) NMD3 PF04981.8 CAR27220.1 - 8.7e-75 250.8 1.5 1.3e-74 250.2 1.0 1.3 1 0 0 1 1 1 1 NMD3 family ThiF PF00899.16 CAR27221.1 - 1.1e-32 112.6 0.0 2.1e-32 111.7 0.0 1.5 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 CAR27221.1 - 0.00043 20.3 0.0 0.002 18.2 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase PDR_assoc PF08370.6 CAR27221.1 - 0.058 12.9 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 Plant PDR ABC transporter associated 2-Hacid_dh_C PF02826.14 CAR27221.1 - 0.099 11.7 0.0 0.84 8.7 0.0 2.1 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 CAR27221.1 - 0.22 10.9 0.0 0.39 10.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Bromodomain PF00439.20 CAR27222.1 - 7.2e-26 89.9 1.9 1.5e-25 88.9 1.3 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 CAR27222.1 - 3.8e-08 33.3 0.3 9.6e-08 32.0 0.2 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CAR27222.1 - 6.6e-08 32.4 0.0 1.3e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Proteasome PF00227.21 CAR27223.1 - 1.7e-53 180.7 0.0 2.3e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CAR27223.1 - 1.4e-13 49.8 0.1 3.9e-13 48.4 0.1 1.8 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Spc97_Spc98 PF04130.8 CAR27224.1 - 1.9e-73 247.6 16.4 2.8e-73 247.0 11.4 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family Enolase_C PF00113.17 CAR27225.1 - 1.1e-148 494.0 0.0 1.5e-148 493.6 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 CAR27225.1 - 6.9e-57 191.0 0.1 1.4e-56 190.0 0.1 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 CAR27225.1 - 0.0069 16.3 0.0 0.028 14.3 0.0 2.0 2 0 0 2 2 2 1 Enolase C-terminal domain-like MAAL_C PF07476.6 CAR27225.1 - 0.018 14.0 0.0 0.041 12.8 0.0 1.5 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 CAR27225.1 - 0.032 14.7 0.0 0.081 13.4 0.0 1.7 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Ctr PF04145.10 CAR27226.1 - 1.6e-28 99.5 12.2 3.9e-26 91.8 8.5 2.1 1 1 0 1 1 1 1 Ctr copper transporter family Rnf-Nqr PF02508.9 CAR27226.1 - 0.025 14.1 0.7 0.065 12.8 0.5 1.7 1 1 0 1 1 1 0 Rnf-Nqr subunit, membrane protein DUF2897 PF11446.3 CAR27226.1 - 0.084 12.7 0.8 0.22 11.4 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Abi PF02517.11 CAR27226.1 - 0.73 10.0 4.1 2.1 8.5 0.3 2.1 2 0 0 2 2 2 0 CAAX protease self-immunity DUF2628 PF10947.3 CAR27226.1 - 0.96 9.2 6.4 5.8 6.7 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) FMO-like PF00743.14 CAR27227.1 - 7.7e-43 146.4 0.0 1e-31 109.7 0.0 2.0 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 CAR27227.1 - 1.7e-15 57.1 0.0 7.4e-15 55.0 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 CAR27227.1 - 4.3e-14 53.0 0.0 7.4e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CAR27227.1 - 1.1e-11 44.9 0.0 1.3e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CAR27227.1 - 1.3e-09 37.4 0.8 2.5e-06 26.6 0.2 3.4 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 CAR27227.1 - 2.1e-07 30.8 0.0 1.3e-06 28.3 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CAR27227.1 - 1.3e-06 27.5 0.0 0.039 12.8 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 CAR27227.1 - 4.6e-05 22.6 0.0 0.0002 20.5 0.0 1.9 2 0 0 2 2 2 1 Thi4 family Mqo PF06039.10 CAR27227.1 - 0.0035 15.5 0.0 0.0067 14.6 0.0 1.4 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) HI0933_like PF03486.9 CAR27227.1 - 0.0053 15.2 0.1 0.12 10.8 0.0 2.5 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_7 PF13241.1 CAR27227.1 - 0.0073 16.5 0.0 0.75 10.0 0.0 2.4 2 1 0 2 2 2 1 Putative NAD(P)-binding Pyr_redox PF00070.22 CAR27227.1 - 0.031 14.6 0.2 14 6.1 0.0 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 CAR27227.1 - 0.12 11.4 0.0 0.7 8.9 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 CAR27227.1 - 0.15 11.0 0.0 0.29 10.1 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Fungal_trans PF04082.13 CAR27228.1 - 4.3e-27 94.6 0.3 6.5e-27 94.0 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR27228.1 - 4.4e-07 29.7 12.3 7.5e-07 28.9 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 CAR27228.1 - 1.2 9.3 11.0 0.31 11.2 4.9 2.1 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Mito_fiss_reg PF05308.6 CAR27228.1 - 9 5.5 8.0 26 4.0 5.1 1.9 2 0 0 2 2 2 0 Mitochondrial fission regulator Oxidored_FMN PF00724.15 CAR27229.1 - 1.4e-120 402.4 0.0 1.6e-120 402.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.15 CAR27230.1 - 5.4e-96 321.5 0.0 7.2e-96 321.1 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Ribosom_S12_S23 PF00164.20 CAR27231.1 - 2.1e-42 143.3 1.2 2.6e-42 143.1 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 PP2C PF00481.16 CAR27232.1 - 4.6e-28 98.2 0.0 2.1e-27 96.1 0.0 1.9 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.1 CAR27232.1 - 9.5e-06 25.1 0.0 8.4e-05 22.0 0.0 2.1 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.7 CAR27232.1 - 0.014 15.1 0.1 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) Ribosomal_S19 PF00203.16 CAR27233.1 - 3.2e-22 77.9 0.0 4.1e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 DEAD PF00270.24 CAR27234.1 - 6.5e-37 126.6 0.3 1.2e-36 125.7 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR27234.1 - 2.7e-18 65.6 0.1 8.4e-18 64.0 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAR27234.1 - 3.1e-06 27.1 0.1 3.1e-06 27.1 0.1 3.4 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 CAR27234.1 - 0.078 12.7 0.3 0.4 10.4 0.1 2.3 1 1 1 2 2 2 0 Flavivirus DEAD domain AAA_22 PF13401.1 CAR27234.1 - 0.51 10.4 5.1 1.1 9.3 1.4 2.9 3 1 0 3 3 3 0 AAA domain Daxx PF03344.10 CAR27234.1 - 6.7 5.0 33.3 11 4.3 23.1 1.2 1 0 0 1 1 1 0 Daxx Family Med12 PF09497.5 CAR27235.1 - 1.3e-24 85.8 0.3 3.7e-24 84.4 0.2 1.9 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Cation_efflux PF01545.16 CAR27236.1 - 7.4e-05 21.9 12.4 0.00032 19.8 8.6 1.9 1 1 0 1 1 1 1 Cation efflux family Pkinase PF00069.20 CAR27237.1 - 1.2e-44 152.4 0.1 1.9e-44 151.8 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR27237.1 - 3.6e-29 101.6 0.1 5.5e-29 101.0 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4299 PF14132.1 CAR27237.1 - 0.012 14.7 0.3 0.021 13.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4299) APH PF01636.18 CAR27237.1 - 0.025 14.3 0.1 1.5 8.4 0.1 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 CAR27237.1 - 0.13 11.2 0.1 0.3 10.0 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Ribosomal_S8 PF00410.14 CAR27238.1 - 7e-26 90.5 0.1 9.5e-26 90.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S11 PF00411.14 CAR27239.1 - 5.7e-40 135.9 0.8 7e-40 135.6 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF814 PF05670.8 CAR27239.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF814) Beach PF02138.13 CAR27241.1 - 1.5e-108 362.3 0.8 4.2e-108 360.8 0.6 1.8 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 CAR27241.1 - 1.5e-12 47.2 0.1 4.4e-12 45.7 0.1 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH TPT PF03151.11 CAR27242.1 - 8e-31 106.7 6.5 8e-31 106.7 4.5 3.5 2 1 2 4 4 4 2 Triose-phosphate Transporter family UAA PF08449.6 CAR27242.1 - 0.00037 19.5 19.0 0.007 15.3 13.2 2.1 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 CAR27242.1 - 0.00057 19.9 31.9 0.0083 16.1 6.8 3.5 3 2 1 4 4 4 2 EamA-like transporter family AAA_22 PF13401.1 CAR27243.1 - 4.2e-10 39.8 0.0 1.2e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 CAR27243.1 - 3.5e-09 36.9 0.6 2.9e-08 33.9 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CAR27243.1 - 6.1e-09 36.1 0.0 2e-08 34.4 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 CAR27243.1 - 4.8e-06 26.2 0.0 3.4e-05 23.4 0.0 2.5 3 1 0 3 3 3 1 Part of AAA domain Cdc6_C PF09079.6 CAR27243.1 - 2e-05 24.1 0.2 0.00012 21.7 0.0 2.4 3 0 0 3 3 3 1 CDC6, C terminal DUF2075 PF09848.4 CAR27243.1 - 0.0034 16.4 0.4 0.0082 15.1 0.0 1.8 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 CAR27243.1 - 0.011 15.4 0.1 0.029 14.0 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase RNA_helicase PF00910.17 CAR27243.1 - 0.011 15.8 0.1 1.7 8.8 0.0 2.9 3 0 0 3 3 3 0 RNA helicase AAA_11 PF13086.1 CAR27243.1 - 0.021 14.3 1.1 0.11 12.0 0.8 2.3 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CAR27243.1 - 0.022 14.2 0.0 0.052 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Myb_DNA-binding PF00249.26 CAR27244.1 - 1.7e-15 56.7 0.0 1.2e-06 28.4 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CAR27244.1 - 0.00011 22.2 0.3 0.049 13.7 0.1 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain CCDC155 PF14662.1 CAR27245.1 - 1.8 8.1 33.8 0.87 9.1 17.9 2.4 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 DUF1664 PF07889.7 CAR27245.1 - 4.4 7.1 20.1 8.1 6.2 3.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Nrap PF03813.9 CAR27246.1 - 0 1220.1 3.6 0 1219.9 2.5 1.0 1 0 0 1 1 1 1 Nrap protein DUF4611 PF15387.1 CAR27246.1 - 0.31 11.2 6.1 0.77 9.9 4.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF1746 PF08508.5 CAR27247.1 - 0.0011 18.9 3.0 0.35 10.8 0.4 3.1 1 1 1 2 2 2 2 Fungal domain of unknown function (DUF1746) RNA_pol_A_bac PF01000.21 CAR27248.1 - 2.8e-29 101.5 0.0 6.6e-29 100.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CAR27248.1 - 3.4e-15 54.8 0.0 4.5e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Nop PF01798.13 CAR27249.1 - 8.8e-38 128.9 0.0 1.6e-37 128.1 0.0 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain Prp31_C PF09785.4 CAR27249.1 - 3.1e-28 98.6 4.8 3.1e-28 98.6 3.4 2.0 2 0 0 2 2 2 1 Prp31 C terminal domain NOSIC PF08060.8 CAR27249.1 - 1.1e-08 34.7 0.1 3e-08 33.3 0.0 1.8 2 0 0 2 2 2 1 NOSIC (NUC001) domain Pkinase PF00069.20 CAR27250.1 - 1.8e-51 174.7 0.1 2.1e-50 171.3 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR27250.1 - 1.9e-27 95.9 0.3 2.6e-19 69.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 CAR27250.1 - 1.1e-05 25.8 0.8 1.1e-05 25.8 0.6 3.2 3 1 1 4 4 4 1 Protein kinase C terminal domain Kinase-like PF14531.1 CAR27250.1 - 0.00048 19.1 0.0 0.0045 15.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CAR27250.1 - 0.034 13.2 0.0 0.065 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CAR27250.1 - 0.1 12.2 0.0 0.32 10.7 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family CwfJ_C_1 PF04677.10 CAR27251.1 - 1.9e-34 117.9 0.3 8.2e-34 115.8 0.1 1.9 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 CAR27251.1 - 6.9e-19 68.1 1.4 6.9e-19 68.1 0.1 1.7 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 DUF1564 PF07600.6 CAR27251.1 - 0.018 14.3 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) UMPH-1 PF05822.7 CAR27251.1 - 0.071 12.4 0.5 0.16 11.2 0.0 1.7 2 0 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) RRM_1 PF00076.17 CAR27252.1 - 2.2e-68 225.8 13.0 5.4e-17 61.1 0.1 6.4 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR27252.1 - 3.8e-61 202.9 3.1 2.7e-14 52.8 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR27252.1 - 1e-37 127.7 0.2 1.6e-09 37.4 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CAR27252.1 - 2.7e-05 23.8 0.0 3.3 7.5 0.0 4.5 5 0 0 5 5 5 2 Nup53/35/40-type RNA recognition motif ClpS PF02617.12 CAR27252.1 - 0.094 12.4 0.0 0.46 10.2 0.0 2.1 2 0 0 2 2 2 0 ATP-dependent Clp protease adaptor protein ClpS Limkain-b1 PF11608.3 CAR27252.1 - 0.2 11.3 2.6 0.78 9.5 0.0 3.3 4 1 1 5 5 5 0 Limkain b1 tRNA-synt_1 PF00133.17 CAR27253.1 - 8.2e-231 767.1 0.9 4.1e-230 764.8 0.6 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CAR27253.1 - 1.7e-32 112.2 0.7 6.2e-32 110.4 0.5 2.0 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CAR27253.1 - 1.4e-16 60.1 0.5 1.3e-07 30.6 0.0 4.3 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 CAR27253.1 - 4.7e-09 35.8 11.8 2.4e-08 33.4 0.0 3.5 3 1 1 4 4 4 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.4 CAR27253.1 - 1.6e-06 28.0 3.1 1.6e-06 28.0 2.1 3.2 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.14 CAR27253.1 - 0.0082 15.2 1.5 0.32 10.0 0.0 3.4 4 1 0 4 4 4 1 tRNA synthetases class I (C) catalytic domain RNase_PH PF01138.16 CAR27254.1 - 4.9e-19 68.9 0.0 7.9e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CAR27254.1 - 2.5e-08 33.7 0.2 7.5e-08 32.2 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Mito_carr PF00153.22 CAR27255.1 - 3.5e-57 190.1 3.1 9e-20 70.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CDP-OH_P_transf PF01066.16 CAR27256.1 - 3.2e-19 69.1 3.6 3.2e-19 69.1 2.5 1.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase ADH_N PF08240.7 CAR27257.1 - 6.1e-31 106.4 0.8 2.5e-30 104.4 0.1 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CAR27257.1 - 5.8e-26 90.5 0.7 8.1e-26 90.0 0.5 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TRAM_LAG1_CLN8 PF03798.11 CAR27258.1 - 3.9e-31 108.1 18.7 6.2e-31 107.4 13.0 1.3 1 0 0 1 1 1 1 TLC domain PH PF00169.24 CAR27259.1 - 6.3e-21 74.5 0.9 2.1e-20 72.8 0.6 2.0 1 0 0 1 1 1 1 PH domain Flavin_Reduct PF01613.13 CAR27260.1 - 1.1e-30 106.5 0.0 1.3e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Peptidase_C50 PF03568.12 CAR27262.1 - 3.8e-117 391.2 0.0 3.8e-117 391.2 0.0 2.9 3 0 0 3 3 3 1 Peptidase family C50 Telomere_reg-2 PF10193.4 CAR27263.1 - 9.9e-25 87.0 0.1 2.7e-24 85.5 0.1 1.8 1 0 0 1 1 1 1 Telomere length regulation protein Fmp27_WPPW PF10359.4 CAR27264.1 - 1.8e-114 382.7 4.4 1.8e-114 382.7 3.1 1.6 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.4 CAR27264.1 - 5.3e-98 328.8 0.0 1.5e-97 327.3 0.0 1.8 1 0 0 1 1 1 1 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.4 CAR27264.1 - 2.1e-45 154.4 0.0 6.5e-45 152.8 0.0 1.9 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 CAR27264.1 - 4.3e-41 140.2 1.8 1.7e-40 138.3 1.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 CAR27264.1 - 8.9e-21 74.2 0.0 5e-20 71.8 0.0 2.5 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain RabGAP-TBC PF00566.13 CAR27265.1 - 2.9e-54 183.8 0.4 7.3e-54 182.4 0.3 1.8 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.15 CAR27265.1 - 1e-13 50.5 0.1 2.7e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 GRAM domain EF-hand_6 PF13405.1 CAR27265.1 - 1.2e-07 31.0 1.6 0.0041 16.8 0.1 3.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 CAR27265.1 - 1.4e-06 28.3 4.0 1.7e-06 28.0 1.0 2.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 CAR27265.1 - 0.00056 19.0 0.5 0.77 9.2 0.1 3.2 3 0 0 3 3 3 2 EF hand Rhomboid PF01694.17 CAR27266.1 - 1.5e-29 102.8 18.2 1.5e-29 102.8 12.6 2.0 2 0 0 2 2 2 1 Rhomboid family Pescadillo_N PF06732.6 CAR27268.1 - 7.6e-124 412.5 3.3 7.6e-124 412.5 2.3 2.7 2 2 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 CAR27268.1 - 3.3e-10 39.9 0.0 5.7e-09 36.0 0.0 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Med18 PF09637.5 CAR27269.1 - 2.4e-61 207.4 0.1 2.7e-61 207.2 0.0 1.0 1 0 0 1 1 1 1 Med18 protein VMA21 PF09446.5 CAR27270.1 - 3.4e-16 58.9 7.6 4.1e-16 58.6 5.2 1.1 1 0 0 1 1 1 1 VMA21-like domain DIE2_ALG10 PF04922.7 CAR27270.1 - 0.012 14.7 0.5 0.012 14.6 0.4 1.1 1 0 0 1 1 1 0 DIE2/ALG10 family YibE_F PF07907.6 CAR27270.1 - 0.026 13.7 0.4 0.029 13.5 0.3 1.0 1 0 0 1 1 1 0 YibE/F-like protein ATP-synt_S1 PF05827.7 CAR27271.1 - 0.00056 19.3 0.0 0.0014 17.9 0.0 1.8 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Telomere_Sde2_2 PF13297.1 CAR27272.1 - 0.018 14.2 1.0 1.4 8.2 0.2 2.9 2 0 0 2 2 2 0 Telomere stability C-terminal Peptidase_C6 PF00851.13 CAR27272.1 - 0.099 11.2 6.6 0.15 10.6 4.4 1.4 1 1 0 1 1 1 0 Helper component proteinase DUF1788 PF08747.6 CAR27272.1 - 1.2 9.0 5.7 0.6 9.9 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1788) IF-2B PF01008.12 CAR27273.1 - 3.4e-82 275.6 0.0 4e-82 275.3 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family HTH_43 PF09904.4 CAR27273.1 - 0.11 12.3 0.0 0.52 10.1 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn helix SKN1 PF03935.10 CAR27274.1 - 5.2e-247 819.9 2.6 6.8e-247 819.5 1.8 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SKN1 PF03935.10 CAR27275.1 - 2.9e-247 820.7 4.0 3.3e-247 820.5 2.8 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SIS PF01380.17 CAR27276.1 - 7.7e-12 44.9 0.0 1.2e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.1 CAR27276.1 - 2.3e-08 33.8 0.0 6.6e-05 22.6 0.0 2.3 1 1 1 2 2 2 2 SIS domain Acid_PPase PF12689.2 CAR27277.1 - 2.9e-43 147.4 0.0 3.5e-43 147.1 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase AcetylCoA_hydro PF02550.10 CAR27278.1 - 4.3e-59 199.6 0.0 6.8e-59 198.9 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 CAR27278.1 - 1.7e-40 138.1 0.0 3.3e-40 137.2 0.0 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CoA_trans PF01144.18 CAR27278.1 - 0.027 13.6 0.0 0.089 11.9 0.0 1.9 2 0 0 2 2 2 0 Coenzyme A transferase Pkinase PF00069.20 CAR27279.1 - 1.4e-72 243.9 0.0 1.7e-72 243.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR27279.1 - 1.5e-31 109.4 0.0 1.9e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR27279.1 - 0.0012 17.8 0.0 0.0024 16.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CAR27279.1 - 0.026 14.2 0.1 0.058 13.1 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 CAR27279.1 - 0.17 10.9 0.2 0.34 9.9 0.1 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BNR PF02012.15 CAR27280.1 - 7.4e-13 46.2 51.4 0.098 12.5 0.1 12.3 12 0 0 12 12 12 7 BNR/Asp-box repeat BNR_2 PF13088.1 CAR27280.1 - 5.4e-11 42.3 0.3 4.8e-05 22.8 0.0 5.6 4 2 1 5 5 5 4 BNR repeat-like domain RFX1_trans_act PF04589.8 CAR27281.1 - 0.12 12.0 0.2 0.16 11.7 0.1 1.1 1 0 0 1 1 1 0 RFX1 transcription activation region Exo_endo_phos PF03372.18 CAR27282.1 - 1.8e-17 64.1 0.0 2.9e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CAR27282.1 - 7.8e-13 48.0 0.0 5.3e-12 45.3 0.0 2.1 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 CAR27282.1 - 1.5e-09 37.5 0.6 3.3e-09 36.5 0.4 1.6 1 0 0 1 1 1 1 GRF zinc finger Rft-1 PF04506.8 CAR27283.1 - 1.4e-169 565.0 33.4 1.7e-169 564.7 23.1 1.0 1 0 0 1 1 1 1 Rft protein NUDIX PF00293.23 CAR27285.1 - 8e-12 44.9 0.0 1.3e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.6 CAR27285.1 - 1.1e-05 24.7 0.1 2.9e-05 23.4 0.1 1.7 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain NUDIX-like PF09296.6 CAR27285.1 - 0.0031 17.8 0.0 0.0057 16.9 0.0 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain GDPD PF03009.12 CAR27286.1 - 1.6e-29 103.1 0.4 1.4e-28 100.1 0.3 1.9 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 CAR27286.1 - 0.044 13.9 0.2 0.13 12.4 0.1 1.9 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family SCA7 PF08313.7 CAR27287.1 - 8.2e-34 115.0 1.6 8.2e-34 115.0 1.1 2.2 2 0 0 2 2 2 1 SCA7, zinc-binding domain Glycos_transf_1 PF00534.15 CAR27288.1 - 2.9e-32 111.4 0.0 2e-31 108.7 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 CAR27288.1 - 1.5e-09 37.8 0.1 5e-09 36.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 CAR27288.1 - 2.3e-06 27.7 0.0 2.3e-05 24.5 0.0 2.3 1 1 1 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CAR27288.1 - 0.0001 22.4 0.0 0.00022 21.4 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain DUF1992 PF09350.5 CAR27289.1 - 6.5e-17 61.1 0.0 2.3e-16 59.3 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) Co_AT_N PF12557.3 CAR27289.1 - 8.5 6.3 11.4 0.34 10.8 3.6 2.0 2 0 0 2 2 2 0 Cob(I)alamin adenosyltransferase N terminal Wyosine_form PF08608.7 CAR27290.1 - 1e-20 73.5 0.0 2.6e-20 72.2 0.0 1.8 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.16 CAR27290.1 - 3.6e-20 72.7 0.0 6.8e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.20 CAR27290.1 - 4.6e-11 42.9 0.0 9.7e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin SET PF00856.23 CAR27291.1 - 0.0004 20.7 0.0 0.0012 19.2 0.0 1.9 1 1 0 1 1 1 1 SET domain zf-H2C2_2 PF13465.1 CAR27294.1 - 3.1e-07 30.3 13.0 3.7e-07 30.1 1.4 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CAR27294.1 - 4.7e-06 26.5 11.1 0.011 15.9 2.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CAR27294.1 - 3.5e-05 23.8 14.6 0.00077 19.6 1.6 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-RING-like PF08746.6 CAR27294.1 - 1.1 9.2 7.6 0.08 12.9 1.7 1.7 2 0 0 2 2 2 0 RING-like domain zf-met PF12874.2 CAR27294.1 - 4.7 7.5 6.1 6.5 7.1 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Coprogen_oxidas PF01218.13 CAR27295.1 - 1.2e-131 437.6 0.2 1.4e-131 437.4 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase TFIIS_C PF01096.13 CAR27296.1 - 6.1e-21 73.7 7.1 7.5e-21 73.4 1.3 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 CAR27296.1 - 1.8e-12 46.7 3.3 2.3e-12 46.3 0.3 2.2 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Elf1 PF05129.8 CAR27296.1 - 0.0095 15.6 3.3 0.28 10.8 0.1 2.4 2 1 0 2 2 2 1 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.2 CAR27296.1 - 0.046 13.5 4.6 3.8 7.3 0.6 2.8 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Terminase_GpA PF05876.7 CAR27296.1 - 0.063 11.6 0.5 0.77 8.0 0.4 2.0 1 1 0 1 1 1 0 Phage terminase large subunit (GpA) PhnA_Zn_Ribbon PF08274.7 CAR27296.1 - 0.078 12.7 6.8 0.95 9.3 0.1 3.2 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zf-piccolo PF05715.8 CAR27296.1 - 0.12 12.4 0.5 0.12 12.4 0.3 2.3 3 0 0 3 3 3 0 Piccolo Zn-finger DUF2387 PF09526.5 CAR27296.1 - 0.17 11.8 2.6 5.6 6.9 0.1 2.4 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) zinc_ribbon_5 PF13719.1 CAR27296.1 - 0.25 10.9 8.8 9.5 5.8 0.3 3.8 3 1 0 3 3 3 0 zinc-ribbon domain Baculo_LEF5_C PF11792.3 CAR27296.1 - 0.78 9.1 3.3 0.84 9.0 0.1 2.4 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain IBR PF01485.16 CAR27296.1 - 1.5 8.7 7.9 2.1 8.2 0.1 2.9 2 1 0 2 2 2 0 IBR domain DZR PF12773.2 CAR27296.1 - 2.8 7.8 6.5 1.5e+02 2.2 4.5 2.7 1 1 0 1 1 1 0 Double zinc ribbon TF_Zn_Ribbon PF08271.7 CAR27296.1 - 3.1 7.2 0.0 3.1 7.2 0.0 2.9 3 1 0 3 3 3 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.5 CAR27296.1 - 5.9 6.9 7.4 33 4.5 0.2 3.6 4 0 0 4 4 4 0 Zinc ribbon domain zinc_ribbon_4 PF13717.1 CAR27296.1 - 9.9 5.9 13.1 11 5.8 0.5 3.9 4 1 0 4 4 4 0 zinc-ribbon domain Trs65 PF12735.2 CAR27297.1 - 1.6e-51 175.4 2.0 3.2e-51 174.4 1.4 1.5 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 Clathrin_lg_ch PF01086.12 CAR27298.1 - 2.4e-40 138.8 12.1 2.6e-40 138.7 8.4 1.0 1 0 0 1 1 1 1 Clathrin light chain Ppx-GppA PF02541.11 CAR27298.1 - 0.046 12.9 0.2 0.058 12.5 0.1 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family DUF3510 PF12022.3 CAR27298.1 - 0.052 13.6 2.0 0.072 13.2 1.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3510) Dna2 PF08696.6 CAR27298.1 - 0.064 12.5 1.2 0.077 12.2 0.9 1.2 1 0 0 1 1 1 0 DNA replication factor Dna2 IFRD PF05004.8 CAR27298.1 - 0.098 11.7 1.4 0.11 11.5 1.0 1.1 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) KIP1 PF07765.7 CAR27298.1 - 0.13 12.1 2.8 7.3 6.5 0.0 2.5 1 1 2 3 3 3 0 KIP1-like protein DDRGK PF09756.4 CAR27298.1 - 0.35 10.2 13.1 0.42 9.9 9.1 1.2 1 0 0 1 1 1 0 DDRGK domain MHC_I PF00129.13 CAR27298.1 - 0.49 9.7 4.5 0.26 10.5 1.1 1.8 1 1 1 2 2 2 0 Class I Histocompatibility antigen, domains alpha 1 and 2 eIF3_N PF09440.5 CAR27298.1 - 0.52 10.4 7.3 0.97 9.5 0.5 2.1 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain DUF87 PF01935.12 CAR27298.1 - 0.57 9.9 2.8 0.65 9.7 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF87 CemA PF03040.9 CAR27298.1 - 0.72 9.4 3.3 0.88 9.1 2.3 1.1 1 0 0 1 1 1 0 CemA family HlyD_2 PF12700.2 CAR27298.1 - 0.82 8.7 6.2 0.9 8.6 4.3 1.1 1 0 0 1 1 1 0 HlyD family secretion protein DUF4065 PF13274.1 CAR27298.1 - 1.2 9.8 5.4 2.1 9.0 3.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4065) HTH_Crp_2 PF13545.1 CAR27299.1 - 0.08 12.7 0.1 0.26 11.1 0.0 1.9 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain SH3_1 PF00018.23 CAR27300.1 - 8.5e-08 31.4 1.8 2.7e-07 29.8 0.1 2.4 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 CAR27300.1 - 5.7e-07 29.0 0.8 1.4e-06 27.7 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 CAR27300.1 - 0.00068 19.0 0.0 0.0016 17.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PseudoU_synth_2 PF00849.17 CAR27301.1 - 3.1e-26 92.1 0.0 5.1e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase Ribosomal_L11 PF00298.14 CAR27303.1 - 1.4 9.1 5.7 0.59 10.3 1.9 1.7 1 1 1 2 2 2 0 Ribosomal protein L11, RNA binding domain DUF3548 PF12068.3 CAR27303.1 - 4.2 6.5 7.0 4.6 6.4 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3548) CAF-1_p150 PF11600.3 CAR27303.1 - 7.1 5.9 32.4 8.3 5.7 22.4 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4355 PF14265.1 CAR27303.1 - 8 6.4 32.8 11 5.9 22.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4355) AATF-Che1 PF13339.1 CAR27304.1 - 5e-29 101.0 3.8 5e-29 101.0 2.6 2.8 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor TRAUB PF08164.7 CAR27304.1 - 1.5e-24 85.8 1.6 5.2e-24 84.1 0.0 2.7 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal PIH1 PF08190.7 CAR27305.1 - 6.5e-24 84.9 1.9 1.2e-23 84.0 1.3 1.4 1 1 0 1 1 1 1 pre-RNA processing PIH1/Nop17 AA_kinase PF00696.23 CAR27306.1 - 2.5e-35 122.1 0.2 3.6e-35 121.6 0.1 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 CAR27306.1 - 2.1e-19 69.0 0.0 4.4e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 PUA domain CPSF_A PF03178.10 CAR27307.1 - 7.3e-84 281.5 0.3 5.9e-83 278.6 0.0 2.4 2 0 0 2 2 2 1 CPSF A subunit region PIG-F PF06699.6 CAR27308.1 - 2.2e-41 141.9 23.4 1.2e-40 139.4 16.2 1.8 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F TauE PF01925.14 CAR27308.1 - 0.29 10.5 10.2 0.57 9.5 7.1 1.6 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE AIM24 PF01987.12 CAR27309.1 - 4.9e-11 42.4 0.0 3.3e-10 39.8 0.0 1.9 1 1 0 1 1 1 1 Mitochondrial biogenesis AIM24 Zn_clus PF00172.13 CAR27310.1 - 5.9e-09 35.6 8.1 1e-08 34.9 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_isomerase PF00160.16 CAR27311.1 - 6.4e-44 149.8 0.3 7.4e-44 149.6 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Med6 PF04934.9 CAR27312.1 - 4.8e-55 184.9 0.0 6.1e-55 184.6 0.0 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component IGR PF09597.5 CAR27313.1 - 2.6e-26 91.3 0.9 5e-26 90.3 0.1 1.8 2 0 0 2 2 2 1 IGR protein motif PRE_C2HC PF07530.6 CAR27313.1 - 0.014 15.2 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Associated with zinc fingers HIT PF01230.18 CAR27314.1 - 2.4e-24 85.7 0.2 4.4e-24 84.8 0.0 1.5 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 CAR27314.1 - 1.8e-07 31.3 0.0 3.4e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 CAR27314.1 - 0.019 14.6 0.0 0.038 13.6 0.0 1.5 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 LemA PF04011.7 CAR27314.1 - 0.058 12.4 0.0 0.096 11.7 0.0 1.3 1 0 0 1 1 1 0 LemA family DUF4337 PF14235.1 CAR27314.1 - 0.19 11.5 1.3 0.27 11.0 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) LRR_5 PF13306.1 CAR27315.1 - 0.0069 16.0 0.0 0.59 9.8 0.0 2.9 2 1 0 2 2 2 1 Leucine rich repeats (6 copies) F-box-like PF12937.2 CAR27315.1 - 0.073 12.8 1.1 0.18 11.5 0.8 1.7 1 0 0 1 1 1 0 F-box-like LRR_8 PF13855.1 CAR27315.1 - 0.24 11.1 7.6 2.5 7.9 0.2 4.5 4 3 0 4 4 4 0 Leucine rich repeat MIR PF02815.14 CAR27316.1 - 1.6e-17 63.6 0.1 2.6e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 MIR domain PMT PF02366.13 CAR27316.1 - 2.4e-12 46.7 20.6 2.4e-12 46.7 14.2 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Med21 PF11221.3 CAR27317.1 - 3.9e-48 163.0 2.8 4.6e-48 162.8 1.9 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex TMCO5 PF14992.1 CAR27317.1 - 0.00058 19.0 4.1 0.00064 18.9 2.9 1.2 1 0 0 1 1 1 1 TMCO5 family Med9 PF07544.8 CAR27317.1 - 0.0026 17.4 0.8 0.0058 16.3 0.3 1.9 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 She9_MDM33 PF05546.6 CAR27317.1 - 0.016 14.8 0.5 0.024 14.2 0.3 1.2 1 0 0 1 1 1 0 She9 / Mdm33 family DUF2200 PF09966.4 CAR27317.1 - 0.022 14.6 0.4 0.91 9.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2200) Peptidase_S49 PF01343.13 CAR27317.1 - 0.073 12.8 0.4 0.2 11.4 0.0 1.9 2 1 0 2 2 2 0 Peptidase family S49 SlyX PF04102.7 CAR27317.1 - 3.7 8.0 6.3 9.2 6.7 0.1 3.1 2 1 1 3 3 3 0 SlyX PBD PF00786.23 CAR27319.1 - 0.0033 17.8 0.1 0.012 16.0 0.1 2.0 1 0 0 1 1 1 1 P21-Rho-binding domain RNase_P_p30 PF01876.11 CAR27320.1 - 1.6e-47 160.4 0.5 2.2e-47 160.0 0.3 1.2 1 0 0 1 1 1 1 RNase P subunit p30 ApbA PF02558.11 CAR27322.1 - 7.5e-32 109.8 0.0 1e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 CAR27322.1 - 5.8e-30 103.8 0.1 8.7e-30 103.2 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NAD_Gly3P_dh_N PF01210.18 CAR27322.1 - 0.00079 19.1 0.0 0.0086 15.8 0.0 2.2 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HSP70 PF00012.15 CAR27323.1 - 3.2e-82 276.3 0.8 1.3e-78 264.4 0.1 2.2 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 CAR27323.1 - 4.9e-12 45.0 0.0 7.4e-12 44.4 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein BSD PF03909.12 CAR27324.1 - 7.6e-26 89.6 3.4 7.2e-14 51.2 0.3 2.6 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 CAR27324.1 - 7e-21 73.6 0.2 1.7e-20 72.4 0.1 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain DEAD PF00270.24 CAR27325.1 - 1.3e-48 164.6 0.0 3.2e-48 163.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR27325.1 - 1.5e-26 92.0 0.0 3.4e-26 90.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAR27325.1 - 9e-08 32.1 0.7 1.9e-06 27.8 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CAR27325.1 - 0.00094 18.8 0.6 0.4 10.4 0.0 3.4 4 0 0 4 4 4 1 Part of AAA domain SecA_DEAD PF07517.9 CAR27325.1 - 0.0068 15.7 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 SecA DEAD-like domain Brix PF04427.13 CAR27326.1 - 9.1e-56 188.5 4.3 1.4e-55 187.9 3.0 1.3 1 0 0 1 1 1 1 Brix domain DUF755 PF05501.6 CAR27326.1 - 4.1 7.4 19.6 0.32 11.0 8.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF755) FYVE PF01363.16 CAR27327.1 - 3.5e-18 65.2 12.7 3.5e-18 65.2 8.8 3.4 3 1 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 CAR27327.1 - 1.2e-09 37.8 5.1 1.2e-09 37.8 3.5 3.6 3 1 0 3 3 3 1 Ring finger domain YdjO PF14169.1 CAR27327.1 - 0.01 15.2 0.4 1.9 8.0 0.0 3.0 2 0 0 2 2 2 0 Cold-inducible protein YdjO FANCL_C PF11793.3 CAR27327.1 - 0.01 15.7 4.6 0.01 15.7 3.2 2.9 3 1 0 3 3 3 0 FANCL C-terminal domain zf-rbx1 PF12678.2 CAR27327.1 - 0.016 15.3 1.9 0.016 15.3 1.3 3.6 3 1 0 3 3 3 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CAR27327.1 - 0.036 13.7 13.3 0.035 13.8 3.3 3.6 3 0 0 3 3 3 0 RING-type zinc-finger zf-C4H2 PF10146.4 CAR27327.1 - 0.076 13.0 2.8 0.74 9.7 0.1 2.8 3 0 0 3 3 3 0 Zinc finger-containing protein zf-Apc11 PF12861.2 CAR27327.1 - 1.7 8.5 11.3 0.1 12.4 1.3 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 CAR27327.1 - 8.4 6.5 31.1 0.097 12.7 4.9 4.0 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) BHD_1 PF10403.4 CAR27328.1 - 8.4e-12 44.4 0.3 5.2e-11 41.8 0.0 2.5 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 CAR27328.1 - 1.8e-10 40.9 1.1 6e-10 39.2 0.8 1.9 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Rad4 PF03835.10 CAR27328.1 - 5.4e-09 35.5 0.1 1.4e-08 34.2 0.1 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 CAR27328.1 - 3.2e-08 33.1 0.0 7.8e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Ins_P5_2-kin PF06090.7 CAR27330.1 - 5.6e-38 130.7 0.4 1.5e-37 129.2 0.3 1.6 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DS PF01916.12 CAR27331.1 - 2.1e-147 490.0 0.0 2.4e-147 489.8 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Methyltransf_23 PF13489.1 CAR27332.1 - 1.1e-16 60.9 0.1 1.8e-16 60.2 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAR27332.1 - 4.1e-12 46.4 0.4 2.3e-11 44.0 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAR27332.1 - 4.8e-08 32.7 0.0 3e-07 30.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CAR27332.1 - 9.5e-08 32.4 0.0 9.4e-06 26.0 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CAR27332.1 - 1.1e-07 31.1 0.0 0.0027 16.8 0.0 2.2 1 1 1 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 CAR27332.1 - 2.3e-07 31.0 0.0 6.3e-07 29.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR27332.1 - 4.5e-07 30.4 0.0 1e-06 29.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ECR1_N PF14382.1 CAR27333.1 - 1e-13 50.3 0.0 2.5e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 CAR27333.1 - 0.0098 15.8 0.0 0.17 11.8 0.0 2.6 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 Met_10 PF02475.11 CAR27334.1 - 5.4e-76 254.6 0.0 1.3e-75 253.3 0.0 1.7 2 0 0 2 2 2 1 Met-10+ like-protein TRM PF02005.11 CAR27334.1 - 0.00076 18.5 0.0 0.0014 17.6 0.0 1.4 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase MethyltransfD12 PF02086.10 CAR27334.1 - 0.0098 15.3 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase PrmA PF06325.8 CAR27334.1 - 0.05 12.7 0.0 0.081 12.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.5 CAR27334.1 - 0.072 12.6 0.0 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.2 CAR27334.1 - 0.11 13.0 0.0 0.2 12.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Cyclin PF08613.6 CAR27335.1 - 4.8e-06 27.0 0.1 6.2e-06 26.6 0.1 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CAR27335.1 - 2.3e-05 23.9 0.3 3.2e-05 23.4 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF3563 PF12086.3 CAR27335.1 - 0.0051 16.5 3.5 0.25 11.0 0.1 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF3563) SUFU PF05076.8 CAR27335.1 - 0.1 12.1 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Suppressor of fused protein (SUFU) GAF_2 PF13185.1 CAR27336.1 - 3.3e-07 30.9 0.0 4e-07 30.6 0.0 1.3 1 1 0 1 1 1 1 GAF domain GAF PF01590.21 CAR27336.1 - 1.2e-05 25.5 0.0 1.7e-05 25.0 0.0 1.3 1 1 0 1 1 1 1 GAF domain PRP4 PF08799.6 CAR27336.1 - 0.026 13.7 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like GAF_3 PF13492.1 CAR27336.1 - 0.069 13.2 0.0 0.16 12.0 0.0 1.7 1 1 0 1 1 1 0 GAF domain DUF285 PF03382.9 CAR27338.1 - 0.0087 15.6 1.8 0.023 14.2 1.3 1.7 1 0 0 1 1 1 1 Mycoplasma protein of unknown function, DUF285 DUF2281 PF10047.4 CAR27338.1 - 0.1 12.9 1.0 0.58 10.4 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2281) WD40 PF00400.27 CAR27339.1 - 1.1e-18 66.3 18.0 3.6e-07 29.8 0.1 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 CAR27339.1 - 0.00066 19.4 1.5 0.31 10.7 0.1 3.2 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A CBS PF00571.23 CAR27340.1 - 6.5e-30 102.6 5.9 1.3e-14 53.7 0.1 4.2 4 0 0 4 4 4 4 CBS domain DUF4342 PF14242.1 CAR27340.1 - 0.014 15.1 0.2 3.6 7.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) HTH_9 PF08221.6 CAR27340.1 - 0.28 11.0 2.9 1.2 9.0 0.1 2.9 4 0 0 4 4 4 0 RNA polymerase III subunit RPC82 helix-turn-helix domain OPT PF03169.10 CAR27341.1 - 1.9e-155 518.8 18.9 2.1e-155 518.6 13.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Imm6 PF14434.1 CAR27341.1 - 0.17 11.5 0.2 0.33 10.6 0.2 1.4 1 0 0 1 1 1 0 Immunity protein Imm6 BCNT PF07572.7 CAR27342.1 - 1.1e-24 86.1 0.6 1.1e-24 86.1 0.4 2.8 3 1 1 4 4 4 1 Bucentaur or craniofacial development Glycolytic PF00274.14 CAR27342.1 - 0.024 13.0 0.0 0.044 12.1 0.0 1.4 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I Astro_capsid PF03115.9 CAR27342.1 - 5.8 5.0 10.0 5.5 5.1 6.3 1.4 1 1 0 1 1 1 0 Astrovirus capsid protein precursor KH_1 PF00013.24 CAR27343.1 - 1.3e-32 111.2 3.1 1.4e-11 43.8 0.3 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 CAR27343.1 - 1.4e-26 91.5 4.7 1.3e-09 37.5 0.4 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 CAR27343.1 - 2.5e-12 46.1 0.4 0.0044 16.5 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 CAR27343.1 - 4.2e-08 32.7 2.1 0.021 14.4 0.1 3.4 3 0 0 3 3 3 2 KH domain DUF354 PF04007.7 CAR27343.1 - 0.0026 16.6 0.2 0.47 9.2 0.0 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF354) SLD3 PF08639.5 CAR27344.1 - 5.8e-74 249.5 11.5 1.4e-73 248.2 7.9 1.6 1 1 0 1 1 1 1 DNA replication regulator SLD3 DUF1546 PF07571.8 CAR27345.1 - 8.6e-31 105.9 0.0 1.9e-30 104.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 CAR27345.1 - 4.7e-30 103.3 0.4 1e-29 102.2 0.3 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 CAR27345.1 - 7.9e-05 22.6 0.1 0.00017 21.6 0.1 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF4 PF05236.9 CAR27345.1 - 0.0045 16.2 0.1 0.0079 15.4 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family CBFD_NFYB_HMF PF00808.18 CAR27345.1 - 0.0059 16.6 0.4 0.018 15.0 0.1 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.10 CAR27345.1 - 0.012 15.4 0.6 0.029 14.1 0.1 1.9 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.1 CAR27345.1 - 0.12 12.5 0.2 0.92 9.7 0.1 2.4 2 0 0 2 2 2 0 Kinetochore component CENP-S DASH_Dad3 PF08656.5 CAR27346.1 - 3.3e-26 90.7 0.5 3.6e-26 90.6 0.3 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad3 PGI PF00342.14 CAR27346.1 - 0.066 11.6 0.0 0.074 11.4 0.0 1.0 1 0 0 1 1 1 0 Phosphoglucose isomerase WD40 PF00400.27 CAR27347.1 - 8.8e-17 60.2 9.4 2.9e-06 26.9 0.2 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat Rax2 PF12768.2 CAR27347.1 - 0.0011 18.2 0.2 0.0022 17.2 0.1 1.5 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Me-amine-dh_H PF06433.6 CAR27348.1 - 0.016 13.8 0.0 1.8 7.1 0.0 2.9 2 1 1 3 3 3 0 Methylamine dehydrogenase heavy chain (MADH) YmzC PF14157.1 CAR27348.1 - 0.034 13.9 0.5 11 5.9 0.0 3.4 3 0 0 3 3 3 0 YmzC-like protein CUE PF02845.11 CAR27349.1 - 8e-08 31.6 0.0 2.1e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 CUE domain UBA_4 PF14555.1 CAR27349.1 - 0.024 14.1 0.0 0.046 13.2 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain Ku PF02735.11 CAR27350.1 - 7e-32 110.4 0.1 1.3e-31 109.5 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 CAR27350.1 - 2.8e-31 108.7 0.6 2.8e-31 108.7 0.4 1.9 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 CAR27350.1 - 3.9e-08 33.6 1.7 1.5e-07 31.8 1.2 2.1 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm VWA PF00092.23 CAR27350.1 - 0.0018 18.0 0.0 0.0046 16.7 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain RecT PF03837.9 CAR27350.1 - 0.0022 17.2 0.1 0.0071 15.6 0.0 1.8 2 0 0 2 2 2 1 RecT family DUF2989 PF11207.3 CAR27350.1 - 0.029 13.8 0.2 1.7 8.0 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2989) Exo_endo_phos PF03372.18 CAR27351.1 - 1.5e-23 83.9 0.3 2e-23 83.5 0.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ribosomal_L30 PF00327.15 CAR27352.1 - 1.1e-14 53.6 0.1 1.9e-14 52.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e SpoIIID PF12116.3 CAR27352.1 - 0.02 14.8 0.1 0.025 14.4 0.1 1.2 1 0 0 1 1 1 0 Stage III sporulation protein D RNB PF00773.14 CAR27354.1 - 1.5e-64 218.3 0.0 2.3e-64 217.7 0.0 1.3 1 0 0 1 1 1 1 RNB domain Pyr_redox_2 PF07992.9 CAR27355.1 - 4.5e-27 95.2 0.2 3.1e-17 63.1 0.0 3.6 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CAR27355.1 - 2.7e-11 43.7 0.0 5.1e-09 36.4 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CAR27355.1 - 7.9e-11 42.4 0.0 7.4e-06 26.1 0.0 3.3 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Cut8_C PF08559.5 CAR27355.1 - 0.0089 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Cut8 six-helix bundle HI0933_like PF03486.9 CAR27355.1 - 0.16 10.4 0.1 14 3.9 0.0 3.0 3 0 0 3 3 3 0 HI0933-like protein Brix PF04427.13 CAR27356.1 - 1.5e-46 158.5 0.6 1.9e-46 158.1 0.4 1.1 1 0 0 1 1 1 1 Brix domain DUF1752 PF08550.5 CAR27357.1 - 2e-10 40.0 0.0 5.8e-10 38.5 0.0 1.9 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) MMPL PF03176.10 CAR27358.1 - 0.0037 16.0 1.2 0.0099 14.6 0.9 1.7 1 0 0 1 1 1 1 MMPL family Apc5 PF12862.2 CAR27358.1 - 1.2 9.0 4.7 7.7 6.4 0.1 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 DUF883 PF05957.8 CAR27358.1 - 4 7.8 23.7 0.19 12.1 2.4 4.9 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF883) DUF2580 PF10824.3 CAR27358.1 - 5.5 7.3 12.7 11 6.4 0.6 4.2 3 1 2 5 5 5 0 Protein of unknown function (DUF2580) DnaJ PF00226.26 CAR27359.1 - 5.3e-22 77.3 2.8 9.4e-22 76.5 2.0 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CAR27359.1 - 2.5e-13 49.7 0.2 1.8e-12 46.9 0.0 2.4 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CAR27359.1 - 1.4e-11 44.2 17.5 4e-11 42.8 12.1 1.8 1 0 0 1 1 1 1 DnaJ central domain DZR PF12773.2 CAR27359.1 - 1.5 8.6 13.1 3.4 7.5 2.1 2.1 1 1 1 2 2 2 0 Double zinc ribbon HypA PF01155.14 CAR27359.1 - 3.7 7.2 10.3 3.8 7.2 0.4 2.8 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family Peptidase_M1 PF01433.15 CAR27360.1 - 6e-86 288.9 2.6 1e-85 288.1 1.8 1.4 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 CAR27360.1 - 6e-74 249.1 0.1 9e-74 248.6 0.1 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 CAR27360.1 - 9.8e-14 51.4 0.1 2.1e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily DUF2265 PF10023.4 CAR27360.1 - 0.00062 19.0 0.0 0.0015 17.7 0.0 1.6 1 0 0 1 1 1 1 Predicted aminopeptidase (DUF2265) Tropomyosin_1 PF12718.2 CAR27362.1 - 5e-49 165.8 48.3 5.9e-49 165.5 33.5 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 CAR27362.1 - 1.1e-07 31.2 43.5 0.00035 19.7 14.3 2.0 1 1 1 2 2 2 2 Tropomyosin KLRAQ PF10205.4 CAR27362.1 - 0.00011 22.1 28.4 0.0039 17.1 8.8 2.1 1 1 1 2 2 2 2 Predicted coiled-coil domain-containing protein CENP-F_leu_zip PF10473.4 CAR27362.1 - 0.00068 19.5 13.9 0.00068 19.5 9.7 2.9 1 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.6 CAR27362.1 - 0.001 18.9 39.5 0.002 17.9 16.3 2.1 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) Myosin_tail_1 PF01576.14 CAR27362.1 - 0.002 15.9 40.8 0.0034 15.1 28.3 1.4 1 1 0 1 1 1 1 Myosin tail WXG100 PF06013.7 CAR27362.1 - 0.0022 17.9 13.9 0.38 10.7 0.1 3.9 2 1 1 3 3 3 1 Proteins of 100 residues with WXG ADIP PF11559.3 CAR27362.1 - 0.0047 16.8 40.7 0.081 12.8 10.3 2.8 1 1 1 2 2 2 2 Afadin- and alpha -actinin-Binding GAS PF13851.1 CAR27362.1 - 0.0047 16.1 42.8 0.12 11.6 13.6 2.4 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding DivIC PF04977.10 CAR27362.1 - 0.0091 15.4 8.0 0.0091 15.4 5.5 4.1 1 1 3 4 4 4 1 Septum formation initiator Laminin_II PF06009.7 CAR27362.1 - 0.0092 15.7 24.8 0.078 12.7 7.4 2.1 1 1 1 2 2 2 2 Laminin Domain II MbeD_MobD PF04899.7 CAR27362.1 - 0.017 14.9 1.7 0.017 14.9 1.2 2.9 2 1 1 3 3 3 0 MbeD/MobD like Filament PF00038.16 CAR27362.1 - 0.021 14.3 35.9 0.042 13.3 11.2 2.0 1 1 1 2 2 2 0 Intermediate filament protein TMF_DNA_bd PF12329.3 CAR27362.1 - 0.026 14.3 52.8 0.052 13.3 12.3 3.1 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 CAR27362.1 - 0.026 13.5 46.0 0.24 10.4 21.3 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Reo_sigmaC PF04582.7 CAR27362.1 - 0.031 13.4 8.0 0.34 10.0 1.5 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein bZIP_1 PF00170.16 CAR27362.1 - 0.034 14.0 41.9 0.6 10.0 3.4 4.6 1 1 2 4 4 4 0 bZIP transcription factor Nup54 PF13874.1 CAR27362.1 - 0.058 13.0 24.1 0.26 10.9 10.9 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Mod_r PF07200.8 CAR27362.1 - 0.074 12.9 35.6 0.18 11.7 8.4 2.9 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein IncA PF04156.9 CAR27362.1 - 0.078 12.5 43.4 0.096 12.2 24.6 2.1 1 1 1 2 2 2 0 IncA protein LPP PF04728.8 CAR27362.1 - 0.096 12.4 0.9 0.97 9.2 0.3 2.6 2 1 0 2 2 2 0 Lipoprotein leucine-zipper BLOC1_2 PF10046.4 CAR27362.1 - 0.11 12.7 31.6 0.54 10.4 6.8 3.9 1 1 1 2 2 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sec2p PF06428.6 CAR27362.1 - 0.12 12.2 37.6 0.07 12.9 14.1 3.2 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p ERM PF00769.14 CAR27362.1 - 0.12 11.8 43.8 0.27 10.7 15.1 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF904 PF06005.7 CAR27362.1 - 0.18 12.1 52.4 0.97 9.7 5.1 3.9 1 1 2 3 3 3 0 Protein of unknown function (DUF904) DUF3287 PF11690.3 CAR27362.1 - 0.18 11.9 18.3 0.11 12.5 4.5 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3287) Atg14 PF10186.4 CAR27362.1 - 0.19 10.6 32.9 0.16 10.9 8.6 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3584 PF12128.3 CAR27362.1 - 0.29 8.4 35.3 0.33 8.2 24.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_27 PF13514.1 CAR27362.1 - 0.33 8.5 30.8 2.7 5.5 21.4 1.9 1 1 0 1 1 1 0 AAA domain EzrA PF06160.7 CAR27362.1 - 0.35 8.9 33.8 0.65 8.1 5.2 2.6 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA Mnd1 PF03962.10 CAR27362.1 - 0.36 10.4 39.3 0.43 10.2 10.6 2.1 1 1 1 2 2 2 0 Mnd1 family TelA PF05816.6 CAR27362.1 - 0.38 9.4 0.1 0.38 9.4 0.1 2.9 1 1 1 2 2 1 0 Toxic anion resistance protein (TelA) Imm15 PF15590.1 CAR27362.1 - 0.4 9.7 3.4 3.7 6.6 0.2 2.7 2 1 0 2 2 2 0 Immunity protein 15 DUF3450 PF11932.3 CAR27362.1 - 0.43 9.7 30.2 0.52 9.5 8.2 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Taxilin PF09728.4 CAR27362.1 - 0.44 9.5 37.8 0.075 12.1 9.4 2.7 1 1 2 3 3 3 0 Myosin-like coiled-coil protein Laminin_I PF06008.9 CAR27362.1 - 0.48 9.6 30.3 0.19 10.9 16.5 2.0 1 1 1 2 2 2 0 Laminin Domain I DUF4200 PF13863.1 CAR27362.1 - 0.53 10.2 44.3 3 7.7 10.8 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) AAA_13 PF13166.1 CAR27362.1 - 0.56 8.5 33.6 0.12 10.8 8.3 2.0 1 1 1 2 2 2 0 AAA domain MIS13 PF08202.6 CAR27362.1 - 0.71 8.8 33.0 1.9 7.4 8.5 2.1 1 1 1 2 2 2 0 Mis12-Mtw1 protein family IFT57 PF10498.4 CAR27362.1 - 0.8 8.3 32.7 0.54 8.9 17.5 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 FlaC_arch PF05377.6 CAR27362.1 - 0.81 9.6 26.9 3 7.8 1.8 4.5 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.7 CAR27362.1 - 0.9 9.8 15.2 8.7 6.6 0.1 3.9 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF972 PF06156.8 CAR27362.1 - 1.1 9.6 34.4 1.5e+04 -6.8 23.9 3.1 1 1 0 1 1 0 0 Protein of unknown function (DUF972) Lebercilin PF15619.1 CAR27362.1 - 1.1 8.6 42.4 0.32 10.4 15.6 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF4201 PF13870.1 CAR27362.1 - 1.2 8.5 38.7 19 4.6 26.8 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) CCDC155 PF14662.1 CAR27362.1 - 1.3 8.5 42.8 0.18 11.3 11.3 2.0 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 Fib_alpha PF08702.5 CAR27362.1 - 1.4 9.0 25.3 3.1 7.9 10.2 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Spc7 PF08317.6 CAR27362.1 - 1.6 7.3 37.3 0.72 8.4 9.8 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Snapin_Pallidin PF14712.1 CAR27362.1 - 2.6 8.3 24.3 2.4 8.5 7.6 3.2 1 1 2 3 3 3 0 Snapin/Pallidin Rootletin PF15035.1 CAR27362.1 - 2.6 7.9 40.1 3.4 7.5 18.8 2.7 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF869 PF05911.6 CAR27362.1 - 2.9 6.0 38.6 0.52 8.4 19.4 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) DUF4407 PF14362.1 CAR27362.1 - 2.9 6.7 20.5 4.3 6.2 14.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2959 PF11172.3 CAR27362.1 - 3 7.5 23.3 40 3.8 16.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2959) TPR_MLP1_2 PF07926.7 CAR27362.1 - 3.7 7.3 45.4 4.4 7.0 21.1 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Spc24 PF08286.6 CAR27362.1 - 3.7 7.2 41.0 0.88 9.2 4.3 4.0 1 1 3 4 4 4 0 Spc24 subunit of Ndc80 DUF1664 PF07889.7 CAR27362.1 - 3.9 7.2 19.7 3.7 7.3 5.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DivIVA PF05103.8 CAR27362.1 - 4 7.4 36.8 4.2 7.4 10.9 3.0 1 1 2 3 3 3 0 DivIVA protein DUF745 PF05335.8 CAR27362.1 - 4.2 6.8 21.6 0.83 9.1 4.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF724 PF05266.9 CAR27362.1 - 4.3 6.9 34.4 1.3 8.5 11.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) PA26 PF04636.8 CAR27362.1 - 4.5 5.8 24.1 1.3 7.6 8.3 2.0 1 1 1 2 2 2 0 PA26 p53-induced protein (sestrin) T2SM PF04612.7 CAR27362.1 - 5.5 6.7 16.8 1.8 8.3 1.9 3.2 1 1 2 3 3 3 0 Type II secretion system (T2SS), protein M Ax_dynein_light PF10211.4 CAR27362.1 - 6.3 6.5 41.0 4.2 7.1 9.1 3.1 1 1 2 3 3 2 0 Axonemal dynein light chain Vps5 PF09325.5 CAR27362.1 - 6.7 5.8 28.7 3.9 6.6 2.0 3.5 1 1 0 2 2 2 0 Vps5 C terminal like TBPIP PF07106.8 CAR27362.1 - 6.7 6.2 38.6 14 5.2 11.9 2.9 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CENP-K PF11802.3 CAR27362.1 - 7 5.7 30.0 0.16 11.1 7.7 2.1 1 1 1 2 2 2 0 Centromere-associated protein K HOOK PF05622.7 CAR27362.1 - 9 3.9 35.6 10 3.7 24.7 1.1 1 0 0 1 1 1 0 HOOK protein DUF342 PF03961.8 CAR27362.1 - 9.3 4.5 35.4 2.4 6.4 9.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) EOS1 PF12326.3 CAR27363.1 - 1.4e-71 238.8 11.3 1.4e-71 238.8 7.9 1.4 2 0 0 2 2 2 1 N-glycosylation protein Ribosomal_S13 PF00416.17 CAR27364.1 - 5.3e-23 81.4 0.1 6.2e-23 81.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 CAR27364.1 - 0.024 13.2 0.0 0.025 13.1 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) IMS_HHH PF11798.3 CAR27364.1 - 0.076 13.0 0.1 0.2 11.7 0.0 1.8 2 0 0 2 2 2 0 IMS family HHH motif DNA_mis_repair PF01119.14 CAR27365.1 - 6.3e-24 83.7 0.4 4.3e-23 81.0 0.1 2.2 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.6 CAR27365.1 - 2.3e-23 82.3 0.0 5.6e-23 81.1 0.0 1.7 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.1 CAR27365.1 - 1.4e-14 53.9 0.1 4.4e-14 52.2 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CAR27365.1 - 2.1e-09 37.0 0.0 4.8e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HORMA PF02301.13 CAR27366.1 - 4.1e-22 78.6 0.8 5.7e-22 78.2 0.5 1.1 1 0 0 1 1 1 1 HORMA domain Mito_carr PF00153.22 CAR27367.1 - 6.1e-63 208.5 1.8 2.3e-20 72.1 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 CAR27367.1 - 6.4e-12 45.4 4.3 4.5e-07 29.8 1.5 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CAR27367.1 - 1.5e-10 40.0 1.9 0.069 13.0 0.0 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.27 CAR27367.1 - 2.5e-09 35.7 2.0 0.043 13.1 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 CAR27367.1 - 3.2e-08 33.0 2.4 2e-05 24.1 0.9 2.9 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 CAR27367.1 - 1.3e-05 24.2 0.1 0.16 11.3 0.0 2.9 2 0 0 2 2 2 2 EF hand 4HBT PF03061.17 CAR27368.1 - 0.00023 21.2 0.3 0.087 12.9 0.1 2.8 3 0 0 3 3 3 2 Thioesterase superfamily Glyco_hydro_101 PF12905.2 CAR27368.1 - 0.018 13.6 0.0 1.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Endo-alpha-N-acetylgalactosaminidase He_PIG PF05345.7 CAR27369.1 - 1.9e-11 43.8 12.5 0.00024 21.0 0.3 4.2 4 0 0 4 4 4 3 Putative Ig domain SKG6 PF08693.5 CAR27369.1 - 6.4e-11 41.3 0.4 6.4e-11 41.3 0.3 2.2 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 CAR27369.1 - 2.1e-05 24.1 0.3 0.00021 20.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) VSP PF03302.8 CAR27369.1 - 0.068 11.8 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein ketoacyl-synt PF00109.21 CAR27369.1 - 0.29 10.5 4.2 0.64 9.4 2.9 1.5 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain EF-hand_4 PF12763.2 CAR27370.1 - 6.9e-52 173.5 4.0 1.3e-49 166.2 1.6 2.4 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand End3 PF12761.2 CAR27370.1 - 9.9e-47 159.1 7.1 5.1e-46 156.7 4.9 1.9 1 1 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 FlxA PF14282.1 CAR27370.1 - 0.0091 15.9 3.4 0.0091 15.9 2.4 2.8 3 0 0 3 3 2 1 FlxA-like protein Gon7 PF08738.5 CAR27370.1 - 0.011 15.6 6.4 0.034 14.1 1.4 2.8 3 0 0 3 3 3 0 Gon7 family EF-hand_1 PF00036.27 CAR27370.1 - 0.023 13.9 1.5 0.11 11.8 1.2 2.1 2 0 0 2 2 2 0 EF hand Prefoldin_2 PF01920.15 CAR27370.1 - 0.031 14.0 6.2 0.26 11.0 0.6 2.8 2 1 0 2 2 2 0 Prefoldin subunit Sugarporin_N PF11471.3 CAR27370.1 - 0.034 13.7 1.1 0.034 13.7 0.7 2.5 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension PilJ PF13675.1 CAR27370.1 - 0.045 14.0 4.2 1 9.7 2.9 2.3 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Syntaxin PF00804.20 CAR27370.1 - 0.047 13.8 5.2 0.054 13.6 2.3 2.1 2 1 0 2 2 1 0 Syntaxin IncA PF04156.9 CAR27370.1 - 0.054 13.0 13.0 0.069 12.7 7.9 1.9 2 1 0 2 2 2 0 IncA protein Cep57_CLD_2 PF14197.1 CAR27370.1 - 0.063 13.2 0.4 0.063 13.2 0.3 2.5 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 FliJ PF02050.11 CAR27370.1 - 0.066 13.2 12.3 0.54 10.3 0.1 2.9 2 1 1 3 3 3 0 Flagellar FliJ protein CCDC144C PF14915.1 CAR27370.1 - 0.068 12.0 7.0 0.57 9.0 0.8 2.3 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region TMF_TATA_bd PF12325.3 CAR27370.1 - 0.073 12.7 7.4 0.66 9.7 5.2 2.2 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Cep57_MT_bd PF06657.8 CAR27370.1 - 0.086 12.7 6.5 2 8.4 0.2 2.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 FlaC_arch PF05377.6 CAR27370.1 - 0.095 12.6 6.0 0.21 11.5 1.0 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Nsp1_C PF05064.8 CAR27370.1 - 0.096 12.3 3.5 0.65 9.6 0.5 2.4 2 0 0 2 2 2 0 Nsp1-like C-terminal region Golgin_A5 PF09787.4 CAR27370.1 - 0.13 10.7 14.0 0.64 8.4 1.2 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 TPR_MLP1_2 PF07926.7 CAR27370.1 - 0.35 10.6 9.9 2.6 7.8 1.9 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein NPV_P10 PF05531.7 CAR27370.1 - 0.37 11.0 3.9 8.7 6.6 0.1 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.1 CAR27370.1 - 0.37 9.7 3.9 0.56 9.1 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Flagellin_N PF00669.15 CAR27370.1 - 0.41 10.4 7.9 0.092 12.5 1.7 2.2 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region DUF342 PF03961.8 CAR27370.1 - 0.72 8.2 3.4 2.2 6.6 2.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Spc24 PF08286.6 CAR27370.1 - 0.75 9.5 7.7 4.2 7.0 0.3 2.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 CCDC-167 PF15188.1 CAR27370.1 - 0.77 9.7 5.8 11 5.9 1.5 2.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 YlbD_coat PF14071.1 CAR27370.1 - 0.97 9.5 6.3 2.1 8.4 0.2 3.1 2 1 1 3 3 3 0 Putative coat protein DUF4164 PF13747.1 CAR27370.1 - 1.4 9.1 6.6 2 8.6 0.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Uds1 PF15456.1 CAR27370.1 - 2.3 8.1 9.0 2.8 7.9 0.8 2.3 2 0 0 2 2 2 0 Up-regulated During Septation Bap31 PF05529.7 CAR27370.1 - 3.2 7.1 6.8 5.6 6.3 0.3 2.3 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like DUF1640 PF07798.6 CAR27370.1 - 4.1 7.3 7.1 8 6.4 4.5 1.9 2 1 0 2 2 1 0 Protein of unknown function (DUF1640) YlqD PF11068.3 CAR27370.1 - 4.7 7.2 8.0 72 3.4 5.5 2.2 1 1 0 1 1 1 0 YlqD protein ATG16 PF08614.6 CAR27370.1 - 5.3 6.8 17.0 3.5 7.4 9.1 2.3 2 1 0 2 2 1 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.5 CAR27370.1 - 5.5 7.1 9.0 19 5.3 4.5 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4140 PF13600.1 CAR27370.1 - 7.5 7.0 9.3 1.2 9.5 0.7 2.7 2 1 1 3 3 2 0 N-terminal domain of unknown function (DUF4140) DUF972 PF06156.8 CAR27370.1 - 8 6.8 7.1 7 7.0 0.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) ADIP PF11559.3 CAR27370.1 - 8.1 6.3 15.2 7.4 6.4 2.0 2.8 2 1 1 3 3 2 0 Afadin- and alpha -actinin-Binding Cpn60_TCP1 PF00118.19 CAR27371.1 - 4.6e-136 454.2 10.7 5.4e-136 454.0 7.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Transposase_23 PF03017.9 CAR27371.1 - 0.007 15.8 0.3 0.038 13.4 0.0 2.4 3 0 0 3 3 3 1 TNP1/EN/SPM transposase V-SNARE PF05008.10 CAR27371.1 - 0.16 12.1 3.9 2.9 8.1 0.2 3.3 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus MKT1_C PF12246.3 CAR27372.1 - 9.6e-63 211.4 4.8 1.6e-62 210.6 3.3 1.4 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 CAR27372.1 - 4.2e-29 100.6 0.0 1.5e-28 98.9 0.0 2.0 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.12 CAR27372.1 - 3e-20 72.3 0.0 1.2e-19 70.3 0.0 2.1 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 CAR27372.1 - 7.1e-08 32.3 0.0 1.5e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 XPG I-region OST3_OST6 PF04756.8 CAR27373.1 - 2.1e-23 82.6 4.8 3.5e-23 81.9 3.3 1.3 1 0 0 1 1 1 1 OST3 / OST6 family Lig_chan PF00060.21 CAR27373.1 - 0.022 14.4 2.9 0.028 14.1 0.6 2.0 2 0 0 2 2 2 0 Ligand-gated ion channel DUF4131 PF13567.1 CAR27373.1 - 0.74 9.1 5.3 1.4 8.2 1.4 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) NfeD PF01957.13 CAR27373.1 - 0.76 9.9 7.9 1.3 9.1 1.0 2.9 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding DUF3382 PF11862.3 CAR27373.1 - 0.94 9.4 4.0 2.6 8.0 0.4 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF3382) Snapin_Pallidin PF14712.1 CAR27374.1 - 6.9e-07 29.4 4.1 9.1e-07 29.1 2.8 1.1 1 0 0 1 1 1 1 Snapin/Pallidin GAS PF13851.1 CAR27374.1 - 0.016 14.4 4.3 0.018 14.2 3.0 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding YscO PF07321.7 CAR27374.1 - 0.016 15.0 2.3 1.1 9.0 0.0 2.0 1 1 1 2 2 2 0 Type III secretion protein YscO Viral_P18 PF04521.8 CAR27374.1 - 0.096 12.1 2.1 0.1 12.0 0.8 1.6 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Reo_sigmaC PF04582.7 CAR27374.1 - 0.12 11.5 0.6 0.14 11.3 0.4 1.0 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Allexi_40kDa PF05549.6 CAR27374.1 - 0.13 11.5 1.5 0.14 11.4 1.0 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein IncA PF04156.9 CAR27374.1 - 0.2 11.2 4.2 0.23 11.0 2.9 1.1 1 0 0 1 1 1 0 IncA protein Fib_alpha PF08702.5 CAR27374.1 - 0.26 11.4 2.8 0.4 10.8 1.9 1.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family KxDL PF10241.4 CAR27374.1 - 0.51 10.2 3.5 1 9.2 2.4 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein HALZ PF02183.13 CAR27374.1 - 1.4 8.6 7.1 0.42 10.3 0.6 2.7 1 1 1 3 3 3 0 Homeobox associated leucine zipper DivIC PF04977.10 CAR27374.1 - 1.7 8.1 6.9 3.8 7.0 0.4 2.3 1 1 1 2 2 2 0 Septum formation initiator C2 PF00168.25 CAR27375.1 - 1.3e-47 159.5 4.0 5.8e-19 67.7 0.0 4.3 4 0 0 4 4 4 3 C2 domain DUF2404 PF10296.4 CAR27375.1 - 0.048 13.7 0.2 0.38 10.9 0.0 2.5 2 1 1 3 3 3 0 Putative integral membrane protein conserved region (DUF2404) COX2-transmemb PF09125.5 CAR27375.1 - 2.3 7.8 4.2 4.8 6.7 2.9 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane DNA_topoisoIV PF00521.15 CAR27376.1 - 9.1e-119 397.0 0.0 3e-118 395.3 0.0 1.9 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 CAR27376.1 - 1.1e-32 112.6 0.5 2.5e-32 111.4 0.3 1.6 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 CAR27376.1 - 9.5e-12 44.7 0.0 3.9e-11 42.7 0.0 2.1 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 CAR27376.1 - 1.2e-09 37.8 0.0 1.8e-08 34.0 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ras PF00071.17 CAR27377.1 - 6.5e-49 165.4 0.0 7.4e-49 165.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR27377.1 - 4.2e-13 49.8 0.0 5.7e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAR27377.1 - 3.8e-08 32.7 0.0 5.1e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.4 CAR27377.1 - 0.00095 18.6 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 CAR27377.1 - 0.031 13.5 0.0 0.35 10.0 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_21 PF13304.1 CAR27377.1 - 0.05 13.5 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CAR27377.1 - 0.077 12.6 0.0 0.13 11.9 0.0 1.4 1 1 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 CAR27377.1 - 0.13 12.1 0.1 4.6 7.1 0.0 2.3 1 1 0 2 2 2 0 AAA domain NST1 PF13945.1 CAR27378.1 - 2.3e-10 40.8 21.3 2.3e-10 40.8 14.8 8.4 4 2 2 7 7 7 1 Salt tolerance down-regulator WBP-1 PF11669.3 CAR27379.1 - 0.066 13.3 0.4 0.33 11.0 0.3 2.2 1 0 0 1 1 1 0 WW domain-binding protein 1 DUF106 PF01956.11 CAR27379.1 - 0.083 12.4 3.9 0.099 12.1 0.1 2.6 2 0 0 2 2 2 0 Integral membrane protein DUF106 DUF3488 PF11992.3 CAR27379.1 - 1.5 7.3 10.0 0.19 10.3 0.7 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3488) N2227 PF07942.7 CAR27380.1 - 1.6e-89 299.5 0.1 2e-89 299.1 0.1 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.7 CAR27380.1 - 0.0038 17.6 0.0 0.013 15.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAR27380.1 - 0.025 14.2 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 CAR27380.1 - 0.027 14.9 0.0 0.088 13.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 CAR27380.1 - 0.037 13.6 0.0 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Ras PF00071.17 CAR27381.1 - 6e-60 201.2 0.0 7.1e-60 201.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR27381.1 - 3.7e-20 72.5 0.0 6.3e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAR27381.1 - 3.4e-17 62.2 0.0 3.8e-17 62.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CAR27381.1 - 1.1e-08 34.4 0.0 1.4e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CAR27381.1 - 2.7e-06 26.9 0.0 5.1e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CAR27381.1 - 4e-05 23.5 0.0 6.2e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PP2C PF00481.16 CAR27382.1 - 2.8e-45 154.7 0.0 5.7e-45 153.6 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C zf-CCCH PF00642.19 CAR27383.1 - 0.001 18.7 0.2 0.001 18.7 0.1 2.4 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CAR27383.1 - 8 6.6 15.5 1.5 8.9 1.5 2.8 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type DUF2183 PF09949.4 CAR27384.1 - 9.5e-31 105.7 0.0 2.6e-30 104.2 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) HPPK PF01288.15 CAR27384.1 - 0.0096 15.6 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) tRNA-synt_2d PF01409.15 CAR27385.1 - 1.3e-44 152.2 0.1 1.8e-25 89.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 CAR27385.1 - 1.4e-24 86.0 0.1 3.5e-24 84.7 0.1 1.7 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain PAS_10 PF13596.1 CAR27385.1 - 0.14 12.4 0.6 0.37 11.0 0.1 1.9 2 0 0 2 2 2 0 PAS domain FAD_binding_1 PF00667.15 CAR27386.1 - 2.2e-27 95.9 0.0 4.7e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CAR27386.1 - 2.4e-21 76.2 0.0 5.9e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 CAR27386.1 - 5.6e-12 46.1 0.0 1.7e-11 44.6 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain ATG11 PF10377.4 CAR27387.1 - 1.9e-39 134.4 0.6 1.9e-39 134.4 0.4 3.1 3 0 0 3 3 3 1 Autophagy-related protein 11 Acetyltransf_1 PF00583.19 CAR27388.1 - 2.5e-18 65.8 0.0 3.8e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 CAR27388.1 - 2.7e-08 33.8 0.0 3.2e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CAR27388.1 - 4.7e-08 33.0 0.0 7.1e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CAR27388.1 - 1.3e-07 31.3 0.1 1.9e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 CAR27388.1 - 1.3e-06 28.5 0.0 1.7e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CAR27388.1 - 1.2e-05 25.4 0.0 1.5e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CAR27388.1 - 1.8e-05 24.6 0.0 4.1e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CAR27388.1 - 0.0089 15.8 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase PCNA_N PF00705.13 CAR27389.1 - 2.1e-51 172.7 1.5 3.9e-51 171.8 1.1 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 CAR27389.1 - 1.7e-49 166.9 0.1 6.4e-49 165.1 0.0 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.11 CAR27389.1 - 1.2e-07 30.8 0.4 4.3e-06 25.7 0.3 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 CAR27389.1 - 0.00045 19.4 0.0 0.00054 19.1 0.0 1.2 1 0 0 1 1 1 1 Rad9 HMG_box PF00505.14 CAR27390.1 - 1.3e-25 89.3 0.6 2.1e-25 88.7 0.4 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CAR27390.1 - 3.1e-18 65.8 0.6 4.7e-18 65.3 0.4 1.3 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 CAR27390.1 - 0.0022 17.7 1.6 0.0024 17.6 0.3 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box 5 DUF1014 PF06244.7 CAR27390.1 - 0.01 16.0 0.2 0.044 13.9 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1014) YABBY PF04690.8 CAR27390.1 - 0.066 13.4 0.5 0.085 13.0 0.2 1.3 1 1 0 1 1 1 0 YABBY protein CHDNT PF08073.7 CAR27390.1 - 0.068 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain zf-Tim10_DDP PF02953.10 CAR27391.1 - 5e-16 57.7 0.1 6.6e-16 57.3 0.0 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger TTL PF03133.10 CAR27392.1 - 8.8e-77 257.9 0.2 1.2e-76 257.4 0.1 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 CAR27392.1 - 7.2e-40 136.4 0.0 1.4e-39 135.4 0.0 1.4 1 0 0 1 1 1 1 Survival protein SurE ATP-grasp_4 PF13535.1 CAR27392.1 - 0.00036 20.3 0.0 0.00089 19.0 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_YheCD PF14398.1 CAR27392.1 - 0.068 11.9 0.0 0.78 8.4 0.0 2.2 2 0 0 2 2 2 0 YheC/D like ATP-grasp RXT2_N PF08595.6 CAR27393.1 - 6.7e-40 136.3 0.7 6.7e-40 136.3 0.5 2.1 2 0 0 2 2 2 1 RXT2-like, N-terminal DUF3461 PF11944.3 CAR27393.1 - 0.021 14.6 0.7 0.034 13.9 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3461) 4HBT_2 PF13279.1 CAR27394.1 - 3e-09 37.3 0.0 4.5e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily DuoxA PF10204.4 CAR27394.1 - 0.13 11.3 1.9 1.6 7.7 0.0 2.1 2 0 0 2 2 2 0 Dual oxidase maturation factor Pkinase PF00069.20 CAR27395.1 - 2.5e-62 210.3 0.7 1.3e-61 208.0 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR27395.1 - 2.3e-30 105.5 0.0 3.3e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 CAR27395.1 - 0.047 12.5 0.0 0.072 11.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.20 CAR27396.1 - 6.1e-28 97.6 0.0 1.3e-27 96.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 CAR27396.1 - 9e-14 50.2 7.2 0.011 15.7 0.0 6.7 6 0 0 6 6 6 2 HEAT repeat Pkinase_Tyr PF07714.12 CAR27396.1 - 1.1e-10 41.0 0.0 1.9e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 CAR27396.1 - 1.6e-08 34.7 0.0 0.0045 17.2 0.0 3.5 1 1 1 3 3 3 3 HEAT repeats WD40 PF00400.27 CAR27396.1 - 0.00089 19.0 0.3 2.2 8.3 0.0 4.4 5 0 0 5 5 5 1 WD domain, G-beta repeat Kinase-like PF14531.1 CAR27396.1 - 0.013 14.4 0.0 0.035 13.0 0.0 1.8 1 1 0 1 1 1 0 Kinase-like HEAT_EZ PF13513.1 CAR27396.1 - 0.026 15.0 1.0 9.5 6.8 0.0 3.7 3 1 1 4 4 4 0 HEAT-like repeat RasGEF_N_2 PF14663.1 CAR27396.1 - 0.046 13.6 0.1 0.36 10.7 0.0 2.5 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain APH PF01636.18 CAR27396.1 - 0.51 10.0 0.0 0.89 9.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sec8_exocyst PF04048.9 CAR27397.1 - 4.4e-45 152.7 5.8 4.4e-45 152.7 4.0 2.7 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain Sec5 PF15469.1 CAR27397.1 - 0.0009 19.0 12.8 0.0012 18.5 1.2 3.9 4 0 0 4 4 4 2 Exocyst complex component Sec5 ERCC4 PF02732.10 CAR27398.1 - 1.8 8.3 10.8 0.37 10.5 2.3 2.6 1 1 1 2 2 2 0 ERCC4 domain Fes1 PF08609.5 CAR27399.1 - 1.3e-28 99.3 1.1 1.3e-28 99.3 0.8 2.4 4 0 0 4 4 4 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 CAR27399.1 - 0.0001 22.5 0.0 0.001 19.2 0.0 2.2 1 1 1 2 2 2 1 HEAT repeats DBB PF14545.1 CAR27399.1 - 0.00021 20.7 0.2 0.00038 19.9 0.1 1.4 1 0 0 1 1 1 1 Dof, BCAP, and BANK (DBB) motif, Arm PF00514.18 CAR27399.1 - 0.0017 18.1 0.0 2.4 8.1 0.0 3.4 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT PF02985.17 CAR27399.1 - 0.0054 16.6 0.0 2.4 8.4 0.0 2.7 2 0 0 2 2 2 1 HEAT repeat V-ATPase_H_C PF11698.3 CAR27399.1 - 0.0087 15.9 0.1 1.2 9.1 0.0 2.7 1 1 1 2 2 2 1 V-ATPase subunit H UME PF08064.8 CAR27399.1 - 0.017 15.0 0.5 2.5 8.0 0.0 3.2 3 1 0 3 3 3 0 UME (NUC010) domain DUF908 PF06012.7 CAR27399.1 - 0.054 12.8 0.0 0.24 10.6 0.0 2.0 1 1 1 2 2 2 0 Domain of Unknown Function (DUF908) HEAT_EZ PF13513.1 CAR27399.1 - 0.069 13.6 0.0 8.2 7.0 0.0 2.8 2 0 0 2 2 2 0 HEAT-like repeat IBN_N PF03810.14 CAR27399.1 - 0.089 12.7 0.2 0.66 9.9 0.0 2.6 2 2 1 3 3 3 0 Importin-beta N-terminal domain Vps51 PF08700.6 CAR27400.1 - 7.9e-11 41.6 2.8 9.4e-11 41.4 0.9 2.0 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.6 CAR27400.1 - 0.0049 16.7 5.8 0.024 14.5 0.3 2.7 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.4 CAR27400.1 - 0.093 12.6 9.1 0.053 13.4 3.5 2.5 2 0 0 2 2 2 0 Golgi transport complex subunit 5 FUSC PF04632.7 CAR27400.1 - 1.5 7.1 2.4 1.5 7.1 0.3 1.9 2 0 0 2 2 2 0 Fusaric acid resistance protein family WD40 PF00400.27 CAR27401.1 - 8.9e-28 95.1 10.1 7.9e-07 28.7 0.6 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 CAR27401.1 - 2.3e-08 33.9 1.8 0.00043 20.0 0.2 4.1 3 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A LisH PF08513.6 CAR27401.1 - 2.9e-05 23.6 0.1 6.5e-05 22.5 0.1 1.7 1 0 0 1 1 1 1 LisH RAB3GAP2_N PF14655.1 CAR27401.1 - 0.0045 16.0 0.0 0.017 14.1 0.0 1.9 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Nup160 PF11715.3 CAR27401.1 - 0.083 11.0 3.0 3 5.8 0.1 3.2 2 2 1 3 3 3 0 Nucleoporin Nup120/160 Tfb4 PF03850.9 CAR27402.1 - 1.5e-105 352.4 0.2 1.8e-105 352.1 0.1 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 VWA_2 PF13519.1 CAR27402.1 - 0.0061 16.6 0.0 0.0082 16.2 0.0 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain Peptidase_C4 PF00863.14 CAR27402.1 - 0.11 11.4 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C4 zf-C2H2 PF00096.21 CAR27403.1 - 0.0039 17.4 3.0 1.5 9.2 0.1 3.4 1 1 2 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CAR27403.1 - 2.4 8.6 7.6 3.4 8.2 0.2 2.9 2 2 0 2 2 2 0 C2H2-type zinc finger Protoglobin PF11563.3 CAR27404.1 - 0.0025 17.4 0.1 0.0048 16.5 0.0 1.5 1 0 0 1 1 1 1 Protoglobin SIP1 PF04938.7 CAR27404.1 - 0.0031 16.8 0.3 0.0093 15.3 0.3 1.7 2 0 0 2 2 2 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) NABP PF07990.7 CAR27404.1 - 0.2 10.9 0.3 3.4 6.8 0.0 2.1 2 0 0 2 2 2 0 Nucleic acid binding protein NABP Mito_carr PF00153.22 CAR27405.1 - 1.9e-54 181.3 3.4 2.3e-20 72.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CM_2 PF01817.16 CAR27406.1 - 6.9e-11 42.0 0.1 9.5e-07 28.8 0.0 4.0 3 1 0 3 3 3 2 Chorismate mutase type II TSNR_N PF04705.7 CAR27406.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.5 2 0 0 2 2 2 0 Thiostrepton-resistance methylase, N terminus DnaJ PF00226.26 CAR27407.1 - 2.1e-13 49.7 0.1 4.2e-13 48.8 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain dCMP_cyt_deam_1 PF00383.17 CAR27408.1 - 1.2e-19 69.8 0.0 1.5e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 CAR27408.1 - 0.0068 16.2 0.6 0.068 13.0 0.4 2.0 1 1 1 2 2 2 1 Bd3614-like deaminase APOBEC_N PF08210.6 CAR27408.1 - 0.012 15.2 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain MafB19-deam PF14437.1 CAR27408.1 - 0.058 13.0 0.0 0.084 12.5 0.0 1.2 1 0 0 1 1 1 0 MafB19-like deaminase AgrB PF04647.10 CAR27409.1 - 0.08 11.9 0.0 0.094 11.7 0.0 1.1 1 0 0 1 1 1 0 Accessory gene regulator B UPF0139 PF03669.8 CAR27409.1 - 0.11 12.0 0.5 0.21 11.1 0.2 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0139) Vac_ImportDeg PF09783.4 CAR27410.1 - 4.7e-67 224.8 0.2 5.9e-67 224.5 0.1 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein HMG_box PF00505.14 CAR27411.1 - 3.6e-17 62.3 0.8 7.2e-17 61.4 0.5 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CAR27411.1 - 2e-07 31.2 0.4 3.3e-07 30.5 0.3 1.4 1 0 0 1 1 1 1 HMG-box domain Abdominal-A PF12407.3 CAR27411.1 - 7.3 6.2 6.3 2.2 7.8 2.1 1.7 2 0 0 2 2 2 0 Homeobox protein Pho88 PF10032.4 CAR27412.1 - 1e-73 246.6 0.2 1.2e-73 246.4 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Solute_trans_a PF03619.11 CAR27412.1 - 0.085 12.1 0.5 4.4 6.5 0.1 2.0 2 0 0 2 2 2 0 Organic solute transporter Ostalpha ThiF PF00899.16 CAR27413.1 - 1.3e-27 96.2 0.0 2.6e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 CAR27413.1 - 1.6e-14 53.2 0.0 3.7e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CAR27413.1 - 4.2e-09 35.6 0.7 1.1e-08 34.3 0.5 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 CAR27413.1 - 0.0014 18.7 0.1 0.0071 16.4 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Fe-S_biosyn PF01521.15 CAR27414.1 - 1.3e-11 44.4 2.7 3e-05 23.9 0.0 2.7 2 1 0 2 2 2 2 Iron-sulphur cluster biosynthesis RNA_pol_3_Rpc31 PF11705.3 CAR27414.1 - 0.012 15.5 3.8 0.015 15.2 2.7 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Tom22 PF04281.8 CAR27414.1 - 0.17 11.4 2.3 0.33 10.4 1.6 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 QueF_N PF14819.1 CAR27415.1 - 0.09 12.8 0.0 0.24 11.5 0.0 1.7 1 1 1 2 2 2 0 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term MscS_porin PF12795.2 CAR27415.1 - 0.22 10.7 2.8 3.7 6.7 0.0 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain S-antigen PF05756.6 CAR27416.1 - 0.16 11.9 1.7 0.27 11.2 1.2 1.2 1 0 0 1 1 1 0 S-antigen protein EF-hand_1 PF00036.27 CAR27417.1 - 6.1e-30 100.2 4.6 1.7e-08 33.1 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CAR27417.1 - 4.6e-27 93.9 0.8 1.9e-13 50.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CAR27417.1 - 6.1e-25 84.8 3.2 6.3e-08 31.8 0.0 4.3 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 CAR27417.1 - 6.8e-19 67.2 5.9 6.8e-09 35.2 0.0 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 CAR27417.1 - 6.2e-17 60.0 3.8 1.9e-07 30.1 0.0 4.3 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.1 CAR27417.1 - 2.6e-12 46.4 0.0 4.1e-08 33.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 CAR27417.1 - 3.6e-06 26.9 0.2 0.0012 18.8 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 CAR27417.1 - 1.7e-05 24.3 0.0 0.14 11.7 0.0 2.7 2 1 0 3 3 3 2 Uncharacterised protein family (UPF0154) Caleosin PF05042.8 CAR27417.1 - 0.00037 20.0 0.0 0.25 10.9 0.0 2.2 2 0 0 2 2 2 2 Caleosin related protein EF-hand_4 PF12763.2 CAR27417.1 - 0.0014 18.3 0.3 0.0044 16.7 0.1 1.8 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand DUF853 PF05872.7 CAR27417.1 - 0.0038 15.6 0.3 0.1 10.9 0.0 2.0 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF853) p25-alpha PF05517.7 CAR27417.1 - 0.019 15.1 0.0 0.76 10.0 0.0 2.1 1 1 1 2 2 2 0 p25-alpha TerB PF05099.8 CAR27417.1 - 0.025 14.2 0.1 0.74 9.5 0.0 2.3 2 1 0 2 2 2 0 Tellurite resistance protein TerB DUF4373 PF14297.1 CAR27417.1 - 0.13 12.6 0.1 2.4 8.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4373) RNA_pol_Rpb4 PF03874.11 CAR27417.1 - 0.13 12.2 0.6 1 9.3 0.0 2.3 2 1 0 2 2 2 0 RNA polymerase Rpb4 Glyco_trans_1_4 PF13692.1 CAR27418.1 - 1.7e-12 47.6 0.0 2.2e-11 44.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 CAR27418.1 - 2.8e-09 36.6 0.0 4.9e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CAR27418.1 - 1.5e-07 31.6 0.0 2.3e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 CAR27418.1 - 0.00034 20.8 0.0 0.00065 19.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Hist_deacetyl PF00850.14 CAR27419.1 - 3e-71 240.2 0.1 5.3e-71 239.4 0.0 1.3 1 1 0 1 1 1 1 Histone deacetylase domain Spermine_synth PF01564.12 CAR27420.1 - 1.1e-99 332.3 0.1 1.4e-99 332.0 0.0 1.0 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 CAR27420.1 - 0.00013 21.5 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAR27420.1 - 0.0036 17.7 0.0 0.015 15.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_30 PF05430.6 CAR27420.1 - 0.02 14.5 0.0 0.041 13.5 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_23 PF13489.1 CAR27420.1 - 0.022 14.4 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 CAR27420.1 - 0.042 14.4 0.0 0.07 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Med1 PF10744.4 CAR27421.1 - 1.4e-69 234.7 7.0 4.5e-68 229.8 4.8 2.2 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 NUDIX PF00293.23 CAR27422.1 - 2e-18 66.3 0.0 3.7e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain EnY2 PF10163.4 CAR27423.1 - 3.2e-25 87.8 1.9 3.7e-25 87.6 1.3 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 USP8_interact PF08941.5 CAR27423.1 - 0.064 12.5 0.0 0.07 12.4 0.0 1.2 1 0 0 1 1 1 0 USP8 interacting DUF1955 PF09205.5 CAR27423.1 - 0.09 12.3 0.2 0.16 11.4 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1955) TPR_11 PF13414.1 CAR27424.1 - 8.2e-53 175.9 40.8 3e-11 42.8 0.3 6.8 2 2 6 8 8 8 8 TPR repeat TPR_1 PF00515.23 CAR27424.1 - 1.7e-49 163.4 23.5 1.8e-07 30.4 0.0 10.9 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.12 CAR27424.1 - 5.8e-42 138.2 27.5 9.4e-05 22.0 0.0 10.7 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_12 PF13424.1 CAR27424.1 - 6.8e-29 99.6 31.7 4.9e-08 32.7 0.2 8.0 3 2 5 8 8 8 8 Tetratricopeptide repeat TPR_17 PF13431.1 CAR27424.1 - 9.6e-29 97.1 23.9 0.00016 21.5 0.1 11.3 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_8 PF13181.1 CAR27424.1 - 3e-26 89.1 16.6 0.052 13.3 0.1 10.4 9 1 1 10 10 10 9 Tetratricopeptide repeat TPR_16 PF13432.1 CAR27424.1 - 1.6e-23 82.8 47.5 5.6e-06 26.8 1.1 8.5 6 2 2 8 8 7 7 Tetratricopeptide repeat TPR_7 PF13176.1 CAR27424.1 - 8.8e-20 68.8 24.5 0.00012 21.6 0.2 9.9 9 1 1 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.1 CAR27424.1 - 2.7e-19 67.8 47.8 0.00011 22.5 0.2 11.5 3 2 8 11 11 10 8 Tetratricopeptide repeat TPR_19 PF14559.1 CAR27424.1 - 1e-12 48.1 44.8 3.2e-05 24.1 0.7 8.2 5 3 3 8 8 7 5 Tetratricopeptide repeat TPR_9 PF13371.1 CAR27424.1 - 5.4e-09 35.7 42.6 6.6e-05 22.6 0.0 7.0 5 2 3 8 8 6 5 Tetratricopeptide repeat TPR_6 PF13174.1 CAR27424.1 - 7.5e-09 35.4 36.2 1.2 9.7 0.0 10.8 10 1 0 10 10 9 3 Tetratricopeptide repeat TPR_15 PF13429.1 CAR27424.1 - 0.00021 20.4 0.4 0.013 14.5 0.0 5.4 2 1 3 5 5 4 3 Tetratricopeptide repeat ChAPs PF09295.5 CAR27424.1 - 0.019 13.7 5.2 0.44 9.2 0.9 3.1 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.1 CAR27424.1 - 0.53 10.2 27.9 0.74 9.8 0.7 8.0 8 0 0 8 8 8 0 Tetratricopeptide repeat SNF2_N PF00176.18 CAR27425.1 - 2e-72 243.5 0.2 2.9e-72 242.9 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CAR27425.1 - 3.4e-11 42.8 0.0 1.3e-10 40.9 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAR27425.1 - 3.8e-09 36.6 0.0 3.8e-09 36.6 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 CAR27425.1 - 2.9e-08 33.2 11.6 2.9e-08 33.2 8.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 CAR27425.1 - 4.2e-07 29.6 0.0 9.8e-07 28.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_2 PF13639.1 CAR27425.1 - 2.5e-05 23.9 9.4 2.5e-05 23.9 6.5 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 CAR27425.1 - 5.6e-05 23.0 9.7 5.6e-05 23.0 6.8 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CAR27425.1 - 0.00029 20.6 10.0 0.00029 20.6 7.0 2.4 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING Shugoshin_C PF07557.6 CAR27425.1 - 0.063 12.7 2.2 0.16 11.4 1.6 1.6 1 0 0 1 1 1 0 Shugoshin C terminus Auto_anti-p27 PF06677.7 CAR27425.1 - 0.1 12.4 4.9 0.53 10.0 0.1 2.8 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-RING_6 PF14835.1 CAR27425.1 - 0.15 11.8 1.9 0.38 10.5 1.3 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Zn_Tnp_IS91 PF14319.1 CAR27425.1 - 0.23 11.0 13.6 0.25 10.8 2.3 2.7 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-RING_5 PF14634.1 CAR27425.1 - 2.2 8.0 23.0 0.018 14.7 7.2 2.4 2 0 0 2 2 2 0 zinc-RING finger domain AMP-binding PF00501.23 CAR27426.1 - 4.8e-72 242.6 0.0 6.5e-72 242.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 CAR27426.1 - 3.3e-70 235.8 0.0 4.7e-70 235.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 CAR27426.1 - 5.3e-15 55.4 0.0 1.2e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 CAR27426.1 - 6.8e-13 48.5 0.0 1.2e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 CAR27426.1 - 6.7e-07 30.1 0.4 2e-05 25.4 0.0 3.0 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 CAR27426.1 - 2.2e-06 26.5 0.0 5.5e-06 25.2 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 CAR27426.1 - 0.023 13.5 0.0 0.067 12.0 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain Not3 PF04065.10 CAR27427.1 - 9.7e-76 254.0 39.8 3.2e-56 190.2 14.1 2.7 2 1 1 3 3 3 2 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 CAR27427.1 - 1.4e-28 99.3 13.5 2.1e-25 89.1 6.3 3.3 2 1 1 3 3 3 2 NOT2 / NOT3 / NOT5 family LMWPc PF01451.16 CAR27428.1 - 1e-42 145.7 0.0 1.1e-42 145.6 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Transketolase_N PF00456.16 CAR27429.1 - 4.1e-141 469.6 0.0 8.8e-141 468.5 0.0 1.5 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 CAR27429.1 - 5.5e-46 156.2 0.0 1.4e-45 154.9 0.0 1.7 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CAR27429.1 - 2.7e-14 53.1 0.0 5.5e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.15 CAR27429.1 - 1.5e-05 23.8 0.0 3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 CAR27429.1 - 0.00044 19.8 0.1 0.0023 17.4 0.0 2.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 CAR27429.1 - 0.0096 14.8 0.3 0.023 13.6 0.2 1.5 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Opy2 PF09463.5 CAR27430.1 - 1.3e-08 34.7 21.0 2e-08 34.1 14.5 1.3 1 0 0 1 1 1 1 Opy2 protein Nop14 PF04147.7 CAR27430.1 - 0.023 12.6 0.1 0.023 12.6 0.0 1.9 2 0 0 2 2 2 0 Nop14-like family FAM176 PF14851.1 CAR27430.1 - 0.034 13.8 0.0 0.034 13.8 0.0 2.6 3 0 0 3 3 3 0 FAM176 family Colicin_V PF02674.11 CAR27430.1 - 0.074 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Colicin V production protein DUF1191 PF06697.7 CAR27430.1 - 0.08 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) PT-VENN PF04829.8 CAR27430.1 - 0.091 12.3 0.2 0.091 12.3 0.2 2.2 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif Cwf_Cwc_15 PF04889.7 CAR27430.1 - 0.14 11.8 7.0 0.052 13.2 0.3 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.9 CAR27430.1 - 9.7 4.0 10.7 0.29 9.1 1.6 1.9 2 0 0 2 2 2 0 CDC45-like protein DUF3074 PF11274.3 CAR27431.1 - 1e-26 93.7 0.0 1.4e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) YopE_N PF09020.5 CAR27432.1 - 0.073 13.1 3.0 1.4 8.9 0.2 2.4 2 0 0 2 2 2 0 YopE, N terminal CIMR PF00878.13 CAR27433.1 - 1.3e-10 41.2 0.9 4.3e-05 23.3 0.1 2.7 2 1 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat PRKCSH_1 PF13015.1 CAR27433.1 - 2.4e-06 27.1 0.1 4.3e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Man-6-P_recep PF02157.10 CAR27433.1 - 0.017 14.1 0.1 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate receptor GTP_EFTU PF00009.22 CAR27434.1 - 1.7e-56 190.6 0.0 2.4e-56 190.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CAR27434.1 - 2.8e-35 120.4 0.0 7.5e-35 119.0 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CAR27434.1 - 1.7e-17 63.2 2.4 5e-17 61.7 1.6 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CAR27434.1 - 6e-05 22.6 0.5 6e-05 22.6 0.3 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 CAR27434.1 - 0.0033 17.3 0.4 0.01 15.8 0.3 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RRM_1 PF00076.17 CAR27435.1 - 2.1e-12 46.4 0.0 8.1e-08 31.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR27435.1 - 1.3e-07 31.4 0.0 0.031 14.2 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR27435.1 - 0.0026 17.5 0.1 1 9.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pex14_N PF04695.8 CAR27435.1 - 0.038 14.0 0.1 0.062 13.3 0.0 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF328 PF03883.9 CAR27436.1 - 0.059 12.6 1.5 0.47 9.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF328) tRNA-synt_2b PF00587.20 CAR27437.1 - 2.1e-68 229.3 0.0 3.5e-68 228.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CAR27437.1 - 5.8e-20 71.0 0.0 1.9e-19 69.3 0.0 2.0 1 0 0 1 1 1 1 Anticodon binding domain DIM1 PF02966.11 CAR27438.1 - 2.2e-69 231.1 1.3 2.5e-69 230.9 0.9 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 CAR27438.1 - 0.00025 20.6 0.1 0.00034 20.2 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CAR27438.1 - 0.032 14.3 0.7 0.053 13.6 0.5 1.4 1 1 0 1 1 1 0 Thioredoxin-like Ribosomal_L31 PF01197.13 CAR27439.1 - 0.0039 17.1 0.0 0.0066 16.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L31 Tau95 PF09734.4 CAR27440.1 - 1.2e-63 215.2 0.8 1.7e-63 214.8 0.6 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit CENP-T PF15511.1 CAR27440.1 - 0.024 13.9 5.9 0.042 13.0 4.1 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T PP2C PF00481.16 CAR27441.1 - 1.3e-59 201.7 0.0 1e-55 188.8 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C DUF658 PF04936.7 CAR27441.1 - 0.0078 16.0 0.1 0.16 11.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF658) Plus-3 PF03126.13 CAR27441.1 - 0.069 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Plus-3 domain Glyco_transf_20 PF00982.16 CAR27442.1 - 1.5e-197 656.7 0.0 1.8e-197 656.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 CAR27442.1 - 0.002 17.5 0.4 0.25 10.7 0.1 2.9 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 CAR27442.1 - 0.14 11.6 0.3 0.29 10.5 0.1 1.6 2 0 0 2 2 2 0 Starch synthase catalytic domain ATP-synt_ab PF00006.20 CAR27444.1 - 1.8e-61 207.3 0.0 2.5e-61 206.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CAR27444.1 - 2.4e-16 60.2 0.3 4.8e-16 59.2 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CAR27444.1 - 2.5e-13 50.0 0.8 5.1e-13 49.0 0.5 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 CAR27444.1 - 0.0011 18.8 0.3 0.0029 17.4 0.2 1.7 1 0 0 1 1 1 1 HAS barrel domain Atg14 PF10186.4 CAR27445.1 - 3.6e-60 203.4 5.2 4.2e-60 203.2 3.6 1.0 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF342 PF03961.8 CAR27445.1 - 0.0099 14.3 6.2 0.014 13.8 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF342) MMR_HSR1 PF01926.18 CAR27446.1 - 0.0013 18.6 0.0 0.22 11.5 0.0 2.6 2 1 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 CAR27446.1 - 0.0095 15.7 0.2 0.66 9.7 0.1 2.3 2 0 0 2 2 2 1 Dynamin family Miro PF08477.8 CAR27446.1 - 0.036 14.5 0.1 0.17 12.3 0.0 2.2 3 0 0 3 3 3 0 Miro-like protein Ras PF00071.17 CAR27446.1 - 0.059 12.7 0.0 0.73 9.2 0.0 2.2 2 0 0 2 2 2 0 Ras family WD40 PF00400.27 CAR27447.1 - 0.0004 20.1 0.0 0.091 12.6 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat PH PF00169.24 CAR27448.1 - 1e-08 35.2 5.7 0.00024 21.2 0.7 3.0 2 1 0 2 2 2 2 PH domain PH_11 PF15413.1 CAR27448.1 - 0.0036 17.5 0.3 0.38 11.0 0.1 2.8 1 1 1 2 2 2 1 Pleckstrin homology domain Filament PF00038.16 CAR27449.1 - 2.3e-05 24.0 26.6 3.3e-05 23.4 18.5 1.2 1 0 0 1 1 1 1 Intermediate filament protein DUF3450 PF11932.3 CAR27449.1 - 0.12 11.6 27.3 0.55 9.4 7.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF4200 PF13863.1 CAR27449.1 - 0.22 11.4 27.0 0.29 11.0 12.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) GAS PF13851.1 CAR27449.1 - 1.6 7.9 34.7 0.65 9.1 13.3 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Spectrin PF00435.16 CAR27449.1 - 1.9 8.8 22.2 1.3 9.3 7.7 2.7 1 1 1 2 2 2 0 Spectrin repeat Tup_N PF08581.5 CAR27449.1 - 5.5 7.2 20.1 0.96 9.6 5.3 3.2 1 1 3 4 4 4 0 Tup N-terminal DUF724 PF05266.9 CAR27449.1 - 7.1 6.1 21.6 0.42 10.1 8.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) TFIIB PF00382.14 CAR27450.1 - 2.6e-36 123.2 1.2 3.8e-24 84.2 0.7 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 CAR27450.1 - 1.1e-12 47.0 1.8 1.8e-12 46.3 1.3 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding SRP54 PF00448.17 CAR27451.1 - 3.8e-79 264.7 2.0 2.5e-78 262.0 0.5 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 CAR27451.1 - 3.1e-25 88.4 10.8 3.1e-25 88.4 7.5 4.2 4 0 0 4 4 4 1 Signal peptide binding domain SRP54_N PF02881.14 CAR27451.1 - 1.4e-14 53.8 3.8 4e-14 52.4 2.6 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 CAR27451.1 - 4.1e-07 29.6 1.3 2.7e-06 26.9 0.2 2.6 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.18 CAR27451.1 - 7.2e-06 25.5 0.2 3.8e-05 23.1 0.1 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 CAR27451.1 - 8e-06 25.8 0.2 0.036 14.0 0.0 3.3 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.1 CAR27451.1 - 9.2e-06 25.5 0.0 3.1e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 CAR27451.1 - 3.1e-05 23.6 0.0 0.0001 22.0 0.0 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 CAR27451.1 - 0.00086 20.1 0.0 0.0017 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.5 CAR27451.1 - 0.0013 17.9 4.8 1.6 7.9 0.1 4.1 3 1 1 4 4 4 2 Signal recognition particle receptor beta subunit AAA_18 PF13238.1 CAR27451.1 - 0.0045 17.2 0.0 0.016 15.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 CAR27451.1 - 0.0052 15.5 0.8 0.016 14.0 0.1 2.2 2 1 0 2 2 2 1 ArgK protein AAA_10 PF12846.2 CAR27451.1 - 0.0064 15.9 0.1 0.014 14.8 0.1 1.5 1 1 0 1 1 1 1 AAA-like domain VirE PF05272.6 CAR27451.1 - 0.011 15.2 0.1 0.03 13.8 0.0 1.7 2 0 0 2 2 2 0 Virulence-associated protein E APS_kinase PF01583.15 CAR27451.1 - 0.016 14.9 0.0 0.041 13.5 0.0 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase MipZ PF09140.6 CAR27451.1 - 0.023 13.7 0.1 0.65 9.0 0.1 2.6 1 1 0 1 1 1 0 ATPase MipZ AAA_22 PF13401.1 CAR27451.1 - 0.024 14.7 0.3 0.16 12.0 0.2 2.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 CAR27451.1 - 0.028 14.5 2.5 0.13 12.4 0.4 2.8 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CAR27451.1 - 0.07 13.1 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 CAR27451.1 - 0.11 12.4 0.1 0.48 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF1712 PF08217.6 CAR27452.1 - 5.8e-137 457.5 0.0 8.3e-120 400.8 0.0 2.1 1 1 1 2 2 2 2 Fungal domain of unknown function (DUF1712) AA_permease PF00324.16 CAR27453.1 - 1.5e-121 406.0 25.0 1.7e-121 405.8 17.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CAR27453.1 - 5e-22 78.0 28.3 6.9e-22 77.5 19.6 1.1 1 0 0 1 1 1 1 Amino acid permease Synaptobrevin PF00957.16 CAR27453.1 - 0.056 13.0 0.4 0.88 9.2 0.0 2.8 3 0 0 3 3 3 0 Synaptobrevin DIL PF01843.14 CAR27454.1 - 2.4e-12 46.6 7.7 1.5e-06 28.0 0.1 3.3 4 0 0 4 4 4 2 DIL domain Ank_5 PF13857.1 CAR27454.1 - 2.1e-10 40.5 0.1 2.7e-06 27.4 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CAR27454.1 - 3e-05 24.2 0.0 6.7e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) GCIP PF13324.1 CAR27454.1 - 3.4 6.8 8.0 54 2.8 0.0 2.8 3 0 0 3 3 3 0 Grap2 and cyclin-D-interacting DUF2457 PF10446.4 CAR27454.1 - 6.1 5.4 13.7 10 4.7 9.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PRMT5 PF05185.11 CAR27455.1 - 8.2e-145 483.1 1.7 1.3e-144 482.5 1.2 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase CKS PF01111.14 CAR27456.1 - 5e-35 119.1 0.1 7.3e-35 118.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit PI3_PI4_kinase PF00454.22 CAR27457.1 - 8e-50 169.4 0.2 2.1e-49 168.1 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.8 CAR27457.1 - 3.8e-31 107.2 2.5 3.8e-31 107.2 1.8 3.0 3 0 0 3 3 3 1 UME (NUC010) domain FATC PF02260.15 CAR27457.1 - 4.3e-13 48.4 0.1 9.4e-13 47.3 0.1 1.6 1 0 0 1 1 1 1 FATC domain TPR_11 PF13414.1 CAR27457.1 - 0.0067 16.0 0.6 0.89 9.2 0.0 3.4 3 0 0 3 3 3 1 TPR repeat TPR_19 PF14559.1 CAR27457.1 - 0.042 14.1 0.1 0.18 12.1 0.1 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat EFP_N PF08207.7 CAR27457.1 - 0.09 12.6 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain DUF429 PF04250.8 CAR27457.1 - 0.18 11.0 0.0 0.47 9.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF429) DUF2404 PF10296.4 CAR27458.1 - 3.1e-29 100.9 0.0 5.9e-29 100.0 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) PH PF00169.24 CAR27458.1 - 6.8e-09 35.8 0.1 2.5e-08 34.0 0.1 2.1 1 0 0 1 1 1 1 PH domain Cofilin_ADF PF00241.15 CAR27460.1 - 1.2e-21 76.8 0.0 5.7e-13 48.8 0.0 2.4 2 1 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein zf-RING_2 PF13639.1 CAR27461.1 - 4.7e-11 42.3 23.5 3.9e-09 36.1 4.9 2.6 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.1 CAR27461.1 - 2e-08 33.7 18.0 1.7e-06 27.6 2.3 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CAR27461.1 - 1.4e-06 27.8 5.1 1.4e-06 27.8 3.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAR27461.1 - 2.7e-05 24.1 5.8 2.7e-05 24.1 4.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CAR27461.1 - 7.4e-05 22.7 4.8 7.4e-05 22.7 3.3 2.9 2 1 1 3 3 3 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CAR27461.1 - 9.7e-05 22.0 4.1 9.7e-05 22.0 2.9 2.7 2 1 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 CAR27461.1 - 0.0062 16.3 2.2 0.0062 16.3 1.5 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 CAR27461.1 - 0.035 13.8 0.7 0.035 13.8 0.5 3.4 3 0 0 3 3 3 0 RING-type zinc-finger PHD PF00628.24 CAR27461.1 - 0.24 11.1 23.3 0.15 11.7 7.3 2.7 2 1 0 2 2 2 0 PHD-finger EURL PF06937.6 CAR27461.1 - 1.2 8.5 6.5 6.6 6.0 0.4 2.8 2 1 1 3 3 3 0 EURL protein FANCL_C PF11793.3 CAR27461.1 - 5.6 7.0 20.6 1.4 8.9 4.1 3.2 2 2 1 3 3 3 0 FANCL C-terminal domain RINGv PF12906.2 CAR27461.1 - 7.1 6.7 24.3 0.27 11.2 3.7 2.6 2 0 0 2 2 2 0 RING-variant domain C1_1 PF00130.17 CAR27461.1 - 7.8 6.3 15.8 0.37 10.5 2.2 3.2 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHF5 PF03660.9 CAR27462.1 - 8.9e-51 170.4 11.8 1e-50 170.2 8.2 1.0 1 0 0 1 1 1 1 PHF5-like protein Sec7 PF01369.15 CAR27463.1 - 8.5e-32 110.3 0.3 1.5e-31 109.5 0.2 1.4 1 0 0 1 1 1 1 Sec7 domain DUF3818 PF12825.2 CAR27464.1 - 1.1e-133 445.1 8.4 2.2e-133 444.1 5.8 1.5 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 CAR27464.1 - 8.6e-49 164.6 0.8 3e-48 162.9 0.6 2.0 1 0 0 1 1 1 1 PX-associated PX PF00787.19 CAR27464.1 - 3.6e-12 46.0 0.1 3.3e-11 42.9 0.0 2.8 3 1 0 3 3 3 1 PX domain SLX9 PF15341.1 CAR27465.1 - 7.8e-20 71.5 13.2 7.8e-20 71.5 9.1 1.6 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 Cut8_N PF14482.1 CAR27465.1 - 0.0011 18.9 1.0 0.0025 17.7 0.7 1.7 1 0 0 1 1 1 1 Cut8 proteasome-binding domain MAS20 PF02064.10 CAR27466.1 - 1.8e-19 69.8 0.1 2.9e-18 65.9 0.0 2.1 1 1 0 1 1 1 1 MAS20 protein import receptor DUF4149 PF13664.1 CAR27467.1 - 1.8e-20 72.8 0.6 2.5e-20 72.4 0.1 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) L51_S25_CI-B8 PF05047.11 CAR27468.1 - 1.2e-13 50.5 0.0 2.1e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain IF-2B PF01008.12 CAR27469.1 - 1.5e-102 342.4 0.1 1.5e-102 342.4 0.1 1.5 2 0 0 2 2 2 1 Initiation factor 2 subunit family DeoRC PF00455.17 CAR27469.1 - 0.0064 16.1 0.0 0.17 11.5 0.0 2.6 2 0 0 2 2 2 1 DeoR C terminal sensor domain EutQ PF06249.7 CAR27469.1 - 4.7 6.7 6.0 1.4 8.4 0.6 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation protein EutQ BCAS2 PF05700.6 CAR27471.1 - 0.00014 21.3 10.4 0.00029 20.3 7.2 1.6 1 1 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) THOC7 PF05615.8 CAR27471.1 - 0.02 15.1 1.3 0.02 15.1 0.9 1.7 2 0 0 2 2 2 0 Tho complex subunit 7 HALZ PF02183.13 CAR27471.1 - 0.04 13.6 4.0 0.066 12.9 0.1 2.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper Ribosomal_L5_C PF00673.16 CAR27472.1 - 8.2e-24 83.1 0.0 1.2e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 CAR27472.1 - 8.9e-20 70.2 0.1 2.2e-19 68.9 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 Tis11B_N PF04553.7 CAR27472.1 - 0.068 13.3 0.6 0.64 10.2 0.0 2.5 1 1 1 3 3 3 0 Tis11B like protein, N terminus ApbA PF02558.11 CAR27472.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Proteasome PF00227.21 CAR27473.1 - 9.1e-49 165.3 0.2 1.1e-48 165.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Fork_head PF00250.13 CAR27474.1 - 4.1e-33 113.2 1.4 7e-33 112.5 0.1 2.0 2 0 0 2 2 2 1 Fork head domain FHA PF00498.21 CAR27474.1 - 5.8e-13 48.7 0.4 1.5e-11 44.2 0.3 2.5 2 0 0 2 2 2 1 FHA domain DUF2457 PF10446.4 CAR27474.1 - 0.0035 16.1 28.8 0.0035 16.1 19.9 5.0 3 1 2 5 5 5 1 Protein of unknown function (DUF2457) COG4 PF08318.7 CAR27475.1 - 3.8e-100 334.8 6.5 6.6e-100 334.0 4.5 1.4 1 0 0 1 1 1 1 COG4 transport protein Bestrophin PF01062.16 CAR27475.1 - 0.058 12.3 4.8 0.076 11.9 0.2 2.6 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel APT PF03440.9 CAR27475.1 - 0.17 11.6 0.2 0.46 10.2 0.1 1.7 1 0 0 1 1 1 0 Aerolysin/Pertussis toxin (APT) domain Pil1 PF13805.1 CAR27476.1 - 9e-154 510.3 0.3 1.1e-153 510.1 0.2 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 zf-CCCH PF00642.19 CAR27477.1 - 2.1e-12 46.3 28.3 0.002 17.7 0.2 5.8 5 1 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CAR27477.1 - 0.0027 17.6 24.6 1.2 9.2 0.5 5.0 4 1 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type RPN7 PF10602.4 CAR27478.1 - 3.4e-53 179.6 3.3 3.4e-53 179.6 2.3 1.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 CAR27478.1 - 2.2e-13 50.4 0.1 1.2e-12 48.0 0.0 2.3 2 1 0 2 2 2 1 PCI domain TPR_12 PF13424.1 CAR27478.1 - 1.2e-05 25.1 0.3 0.0039 17.1 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 CAR27478.1 - 0.00055 19.6 1.2 0.044 13.7 0.3 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 CAR27478.1 - 0.0018 18.7 0.1 0.36 11.5 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF357 PF04010.8 CAR27478.1 - 0.0021 17.7 0.1 0.0056 16.3 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF357) TPR_7 PF13176.1 CAR27478.1 - 0.003 17.2 0.6 0.42 10.5 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 CAR27478.1 - 0.0039 16.8 0.4 0.024 14.2 0.1 2.3 2 0 0 2 2 2 1 TPR repeat TPR_8 PF13181.1 CAR27478.1 - 0.0042 16.7 0.3 0.016 14.9 0.2 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_15 PF13429.1 CAR27478.1 - 0.0074 15.3 0.2 0.018 14.1 0.1 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat PCI_Csn8 PF10075.4 CAR27478.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 DUF706 PF05153.10 CAR27478.1 - 0.026 13.8 0.1 0.061 12.6 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF706) Interferon PF00143.14 CAR27478.1 - 0.059 13.2 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Interferon alpha/beta domain TPR_1 PF00515.23 CAR27478.1 - 0.47 10.1 5.0 0.45 10.2 0.5 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Catalase PF00199.14 CAR27479.1 - 2.8e-148 493.7 0.2 2.1e-147 490.8 0.2 2.0 1 1 0 1 1 1 1 Catalase Catalase-rel PF06628.7 CAR27479.1 - 2.8e-15 55.9 0.0 1.3e-14 53.7 0.0 2.2 2 0 0 2 2 2 1 Catalase-related immune-responsive ELO PF01151.13 CAR27480.1 - 5.4e-61 206.0 23.6 6.5e-61 205.7 16.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family RNase_PH PF01138.16 CAR27481.1 - 5.1e-27 94.7 0.0 1.5e-26 93.2 0.0 1.8 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CAR27481.1 - 0.14 12.1 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 PfkB PF00294.19 CAR27482.1 - 1.4e-47 162.3 3.7 4.3e-47 160.6 2.6 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase UCH PF00443.24 CAR27483.1 - 3.3e-89 298.5 0.1 1e-87 293.6 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CAR27483.1 - 3.7e-23 82.4 0.7 1.4e-13 50.9 0.8 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 CAR27483.1 - 0.0053 17.1 0.0 0.0053 17.1 0.0 3.4 3 1 0 3 3 3 1 DUSP domain SPX PF03105.14 CAR27484.1 - 1.1e-45 156.5 3.3 1.1e-45 156.5 2.3 1.7 2 1 0 2 2 2 1 SPX domain Na_sulph_symp PF00939.14 CAR27484.1 - 7.2e-28 97.6 35.9 1.1e-27 97.1 24.9 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 CAR27484.1 - 1.2e-13 50.3 20.1 1.2e-13 50.3 13.9 2.4 2 1 1 3 3 3 1 Citrate transporter ATPase_gene1 PF09527.5 CAR27484.1 - 0.18 11.6 7.0 0.033 13.9 1.1 2.7 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) Aconitase PF00330.15 CAR27485.1 - 3.7e-172 573.0 0.0 1.1e-171 571.4 0.0 1.8 2 1 0 2 2 2 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CAR27485.1 - 2.9e-43 147.1 0.0 5.6e-43 146.1 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain RasGEF PF00617.14 CAR27486.1 - 3.9e-48 163.6 0.5 9.1e-48 162.4 0.3 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 CAR27486.1 - 4.1e-16 58.9 0.2 2.5e-15 56.4 0.2 2.4 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 CAR27486.1 - 4.2e-06 26.0 0.0 9.4e-06 24.9 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CAR27486.1 - 0.0019 17.7 0.0 0.0061 16.1 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 CAR27486.1 - 0.0031 16.9 0.0 0.0063 15.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain CRAL_TRIO_2 PF13716.1 CAR27487.1 - 5.1e-31 107.6 1.5 2e-30 105.6 1.0 2.0 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain RhoGAP PF00620.22 CAR27487.1 - 1.6e-08 34.3 0.2 7.1e-08 32.1 0.2 2.1 1 0 0 1 1 1 1 RhoGAP domain PRP21_like_P PF12230.3 CAR27488.1 - 1.5e-33 116.2 8.2 5.1e-21 75.2 1.6 2.2 1 1 1 2 2 2 2 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 CAR27488.1 - 1.1e-13 50.5 3.6 6.5e-07 28.9 0.1 2.9 4 0 0 4 4 4 2 Surp module CSD PF00313.17 CAR27488.1 - 0.057 13.2 0.4 0.92 9.3 0.1 2.5 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain Sec10 PF07393.6 CAR27489.1 - 5.5e-69 233.1 24.8 6.9e-69 232.7 17.2 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 TetR_C_8 PF14278.1 CAR27489.1 - 0.0061 16.9 1.3 0.0061 16.9 0.9 4.6 4 0 0 4 4 4 1 Transcriptional regulator C-terminal region Spore_III_AB PF09548.5 CAR27489.1 - 0.15 11.8 14.9 0.54 9.9 3.1 3.6 3 1 1 4 4 4 0 Stage III sporulation protein AB (spore_III_AB) Fungal_trans PF04082.13 CAR27490.1 - 3.4e-33 114.6 2.3 5e-33 114.0 1.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR27490.1 - 2.8e-09 36.7 13.6 6e-09 35.6 9.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 CAR27490.1 - 0.0024 16.5 0.5 0.0024 16.5 0.3 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain HEAT PF02985.17 CAR27491.1 - 0.00029 20.6 0.9 0.45 10.7 0.0 4.1 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 CAR27491.1 - 0.089 13.0 0.5 2.2 8.6 0.0 3.0 3 0 0 3 3 3 0 HEAT repeats Endonuclease_NS PF01223.18 CAR27492.1 - 3e-60 203.3 0.0 3.6e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease PPR_3 PF13812.1 CAR27493.1 - 0.06 13.6 0.0 35 5.0 0.0 3.1 2 0 0 2 2 2 0 Pentatricopeptide repeat domain Pex2_Pex12 PF04757.9 CAR27494.1 - 2e-12 47.0 12.5 4.6e-12 45.8 8.7 1.5 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 CAR27494.1 - 0.91 9.6 17.4 1.7 8.7 12.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_clus PF00172.13 CAR27495.1 - 6.3e-07 29.2 9.4 6.3e-07 29.2 6.5 2.5 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.22 CAR27496.1 - 1.7e-61 203.9 1.6 8.7e-21 73.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1217 PF06748.7 CAR27496.1 - 0.08 13.0 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1217) ATG27 PF09451.5 CAR27497.1 - 0.15 11.3 0.8 0.28 10.4 0.3 1.4 1 1 1 2 2 2 0 Autophagy-related protein 27 Homeobox PF00046.24 CAR27498.1 - 2.6e-10 39.7 0.3 8.1e-10 38.1 0.0 1.9 2 0 0 2 2 2 1 Homeobox domain ApbA_C PF08546.6 CAR27499.1 - 1.6e-29 102.4 0.0 2.8e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 CAR27499.1 - 2.6e-26 91.8 0.1 3.5e-26 91.4 0.1 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Fungal_trans_2 PF11951.3 CAR27500.1 - 6.3e-54 183.0 0.3 7.7e-54 182.7 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR27500.1 - 0.00015 21.5 10.1 0.00027 20.7 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribonuc_L-PSP PF01042.16 CAR27501.1 - 4.7e-25 87.6 0.0 5.6e-25 87.4 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Flavodoxin_2 PF02525.12 CAR27502.1 - 4.4e-47 160.1 0.0 5.3e-47 159.9 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 CAR27502.1 - 7.3e-13 48.2 0.0 1.2e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.2 CAR27502.1 - 0.0019 17.5 0.3 0.0029 16.9 0.2 1.3 1 0 0 1 1 1 1 Flavodoxin Aminotran_3 PF00202.16 CAR27503.1 - 2.7e-57 194.1 0.0 3.3e-57 193.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III AA_permease PF00324.16 CAR27504.1 - 3.4e-107 358.7 39.2 4.2e-107 358.4 27.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CAR27504.1 - 8.4e-28 97.0 43.7 1.4e-27 96.3 30.3 1.3 1 0 0 1 1 1 1 Amino acid permease FMN_dh PF01070.13 CAR27505.1 - 1.1e-91 307.3 0.0 4.1e-91 305.5 0.0 1.7 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 CAR27505.1 - 3.5e-19 68.3 0.0 9.8e-19 66.9 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 CAR27505.1 - 1.3e-07 30.8 0.0 2.7e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 CAR27505.1 - 8.7e-05 21.5 0.4 0.0012 17.8 0.1 2.2 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 CAR27505.1 - 0.01 15.1 0.3 1.2 8.3 0.0 2.2 1 1 1 2 2 2 0 Histidine biosynthesis protein NMO PF03060.10 CAR27505.1 - 0.041 13.0 0.2 0.11 11.6 0.1 1.4 1 1 0 1 1 1 0 Nitronate monooxygenase Gly_kinase PF02595.10 CAR27505.1 - 0.12 11.0 0.0 0.21 10.2 0.0 1.3 1 0 0 1 1 1 0 Glycerate kinase family UK PF02512.9 CAR27505.1 - 0.14 12.5 0.2 0.36 11.2 0.1 1.7 1 0 0 1 1 1 0 Virulence determinant Epimerase PF01370.16 CAR27506.1 - 9.4e-23 80.8 0.0 1.7e-22 80.0 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CAR27506.1 - 9.7e-15 54.1 0.0 2.3e-13 49.6 0.0 2.5 1 1 1 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 CAR27506.1 - 6.8e-14 51.2 0.0 9.7e-14 50.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CAR27506.1 - 3e-12 46.9 0.0 9.9e-12 45.2 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 CAR27506.1 - 4.5e-07 29.0 0.0 2.4e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 CAR27506.1 - 3.1e-05 23.9 0.0 0.00013 21.8 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 CAR27506.1 - 6.7e-05 22.2 0.0 0.00043 19.6 0.0 2.1 2 1 0 2 2 2 1 NmrA-like family KR PF08659.5 CAR27506.1 - 0.001 18.7 0.0 0.0024 17.5 0.0 1.6 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 CAR27506.1 - 0.0023 16.8 0.0 0.0034 16.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain OPT PF03169.10 CAR27507.1 - 6.6e-121 404.7 42.8 7.6e-121 404.5 29.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUP PF00674.13 CAR27508.1 - 4.7e-27 94.0 4.1 2.6e-15 56.3 0.2 2.3 2 0 0 2 2 2 2 DUP family Lysis_S PF04971.7 CAR27508.1 - 0.033 13.8 0.2 0.061 13.0 0.1 1.4 1 0 0 1 1 1 0 Lysis protein S BNR PF02012.15 CAR27509.1 - 2.4e-10 38.6 16.6 0.22 11.5 0.2 8.0 7 0 0 7 7 7 4 BNR/Asp-box repeat Mo-co_dimer PF03404.11 CAR27509.1 - 4.7e-05 23.0 0.1 8.9 5.9 0.0 4.8 5 0 0 5 5 5 3 Mo-co oxidoreductase dimerisation domain PSII_BNR PF14870.1 CAR27509.1 - 0.0031 16.5 0.1 0.028 13.4 0.0 2.5 4 0 0 4 4 4 1 Photosynthesis system II assembly factor YCF48 DUP PF00674.13 CAR27510.1 - 1.3e-27 95.8 1.1 1.7e-12 47.2 0.3 2.4 2 0 0 2 2 2 2 DUP family Erythrovirus_X PF06795.6 CAR27510.1 - 0.059 13.4 0.6 0.18 11.8 0.4 1.8 1 0 0 1 1 1 0 Erythrovirus X protein Phage_tail_X PF05489.7 CAR27510.1 - 0.075 12.5 0.0 0.21 11.0 0.0 1.7 1 0 0 1 1 1 0 Phage Tail Protein X DUP PF00674.13 CAR27511.1 - 2.1e-05 24.4 1.3 2.1e-05 24.4 0.9 2.2 2 0 0 2 2 2 1 DUP family DUP PF00674.13 CAR27512.1 - 2.4e-08 33.8 0.3 2.4e-08 33.8 0.2 2.5 2 1 2 4 4 4 1 DUP family DUP PF00674.13 CAR27513.1 - 3.2e-25 88.1 5.0 3.3e-15 55.9 0.0 2.6 2 1 0 2 2 2 2 DUP family DUF1360 PF07098.6 CAR27513.1 - 0.021 14.5 0.2 0.055 13.1 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) DUP PF00674.13 CAR27514.1 - 3.2e-07 30.2 0.4 3.2e-07 30.2 0.3 2.3 2 0 0 2 2 2 1 DUP family zf-C4 PF00105.13 CAR27514.1 - 0.13 12.4 1.0 0.29 11.3 0.7 1.5 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) Shisa PF13908.1 CAR27514.1 - 1.9 8.6 4.9 1.4 9.0 0.5 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator MFS_1 PF07690.11 CAR27515.1 - 1.4e-32 112.8 42.6 1.4e-32 112.8 29.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CAR27515.1 - 1.9e-09 36.6 38.0 6.7e-09 34.8 26.3 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter OPT PF03169.10 CAR27516.1 - 5.8e-151 503.9 45.1 7.1e-151 503.7 31.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUP PF00674.13 CAR27517.1 - 5.2e-30 103.5 4.4 2.4e-16 59.6 0.3 2.5 2 0 0 2 2 2 2 DUP family CoA_binding_3 PF13727.1 CAR27517.1 - 0.0088 15.8 1.8 2.5 7.8 0.0 2.4 2 0 0 2 2 2 2 CoA-binding domain DUF2619 PF10942.3 CAR27517.1 - 0.051 13.5 0.7 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2619) Tmemb_9 PF05434.6 CAR27517.1 - 0.072 12.8 0.3 0.072 12.8 0.2 1.7 1 1 1 2 2 2 0 TMEM9 DUF747 PF05346.6 CAR27517.1 - 0.085 11.8 0.1 0.085 11.8 0.0 1.6 2 0 0 2 2 2 0 Eukaryotic membrane protein family DHO_dh PF01180.16 CAR27518.1 - 3.9e-90 301.8 0.0 4.4e-90 301.6 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 CAR27518.1 - 8.6e-06 24.8 0.0 0.0001 21.2 0.0 2.1 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Polysacc_deac_1 PF01522.16 CAR27518.1 - 0.00057 19.5 0.0 0.0024 17.4 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide deacetylase PcrB PF01884.12 CAR27518.1 - 0.037 13.2 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 PcrB family DUF885 PF05960.6 CAR27518.1 - 0.11 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) GST_N PF02798.15 CAR27519.1 - 6.2e-12 45.5 0.0 1.2e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CAR27519.1 - 1.4e-07 31.5 0.0 3.7e-07 30.2 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CAR27519.1 - 2.9e-07 30.4 0.0 6.4e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CAR27519.1 - 7.8e-07 28.9 0.0 1.7e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CAR27519.1 - 3.2e-05 24.3 0.0 7.1e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CAR27519.1 - 0.0013 18.5 0.0 0.0029 17.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Aminotran_5 PF00266.14 CAR27520.1 - 1.7e-18 66.5 0.0 2.4e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 CAR27520.1 - 0.00076 18.5 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Pyridoxal_deC PF00282.14 CAR27520.1 - 0.0018 16.7 0.0 0.0029 16.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.12 CAR27520.1 - 0.03 13.3 0.0 0.16 10.9 0.0 1.9 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Glutaredoxin PF00462.19 CAR27520.1 - 0.078 12.9 0.1 0.23 11.4 0.1 1.8 1 0 0 1 1 1 0 Glutaredoxin DUF2805 PF10985.3 CAR27520.1 - 0.081 12.8 0.0 0.74 9.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) Pkinase PF00069.20 CAR27522.1 - 0.018 14.1 0.0 0.037 13.1 0.0 1.5 2 0 0 2 2 2 0 Protein kinase domain adh_short PF00106.20 CAR27523.1 - 4.9e-31 107.8 0.2 6.9e-31 107.4 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CAR27523.1 - 4.1e-16 59.4 0.1 5.2e-16 59.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CAR27523.1 - 4.3e-14 52.5 0.4 5.8e-14 52.1 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CAR27523.1 - 3.7e-07 29.8 0.1 3.2e-06 26.7 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 CAR27523.1 - 0.00029 19.8 0.2 0.00038 19.4 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein TrkA_N PF02254.13 CAR27523.1 - 0.0014 18.6 0.1 0.0022 17.9 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_10 PF13460.1 CAR27523.1 - 0.0014 18.6 0.9 0.0066 16.4 0.6 2.0 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 CAR27523.1 - 0.0025 16.7 0.1 0.013 14.4 0.1 1.9 1 1 0 1 1 1 1 Male sterility protein DapB_N PF01113.15 CAR27523.1 - 0.031 14.2 0.6 0.49 10.3 0.4 2.6 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus PP2C_2 PF13672.1 CAR27523.1 - 0.041 13.2 0.1 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein phosphatase 2C ATP-synt_B PF00430.13 CAR27523.1 - 0.06 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) GYD PF08734.6 CAR27523.1 - 0.069 12.8 0.1 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 GYD domain 3Beta_HSD PF01073.14 CAR27523.1 - 0.092 11.4 0.2 0.13 10.9 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ADK PF00406.17 CAR27524.1 - 4.1e-46 156.6 0.1 5.3e-46 156.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 CAR27524.1 - 2.5e-09 37.5 0.0 4.6e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CAR27524.1 - 2.8e-09 37.0 0.0 6.2e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CAR27524.1 - 4.2e-06 27.5 0.0 6.6e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 CAR27524.1 - 0.00043 19.7 0.0 0.00069 19.1 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Thymidylate_kin PF02223.12 CAR27524.1 - 0.0018 17.7 1.1 1.2 8.5 0.1 2.3 2 0 0 2 2 2 2 Thymidylate kinase Zeta_toxin PF06414.7 CAR27524.1 - 0.028 13.5 0.0 0.044 12.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin TPR_1 PF00515.23 CAR27526.1 - 6.9e-35 117.2 5.0 1.1e-05 24.8 0.0 9.3 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.12 CAR27526.1 - 2.6e-32 108.1 7.3 0.00083 19.0 0.0 9.8 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_11 PF13414.1 CAR27526.1 - 3.6e-31 106.6 5.5 2.4e-11 43.0 0.1 6.9 5 1 2 7 7 7 6 TPR repeat Apc3 PF12895.2 CAR27526.1 - 3.8e-27 94.2 18.7 1.2e-20 73.4 0.0 5.6 4 2 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CAR27526.1 - 1.1e-21 74.9 8.0 0.0003 20.3 0.2 8.4 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 CAR27526.1 - 3.4e-21 75.3 0.0 2.3e-06 28.1 0.0 6.8 6 1 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 CAR27526.1 - 7.5e-21 73.8 17.4 2.8e-10 39.9 0.0 8.5 5 3 4 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 CAR27526.1 - 1e-18 66.1 1.9 0.0073 16.8 0.0 8.6 5 2 4 9 9 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 CAR27526.1 - 1.7e-16 60.2 7.6 0.00034 20.9 0.0 6.8 4 2 2 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 CAR27526.1 - 4.5e-16 57.6 0.7 0.025 14.7 0.0 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.1 CAR27526.1 - 7.7e-15 53.4 13.4 8e-05 22.1 0.0 8.3 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_10 PF13374.1 CAR27526.1 - 1.9e-12 46.6 1.5 0.019 14.9 0.0 6.1 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 CAR27526.1 - 5.7e-10 38.9 0.2 0.00017 21.3 0.0 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 CAR27526.1 - 4.8e-08 32.4 2.5 0.0029 16.6 0.2 3.2 2 2 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 CAR27526.1 - 2.4e-05 24.5 12.5 0.8 10.3 0.0 7.3 9 0 0 9 9 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CAR27526.1 - 0.00018 21.3 8.4 4.2 7.3 0.2 5.2 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat Foie-gras_1 PF11817.3 CAR27526.1 - 0.034 13.6 0.1 0.14 11.6 0.1 2.1 1 0 0 1 1 1 0 Foie gras liver health family 1 TPR_4 PF07721.9 CAR27526.1 - 0.06 13.7 2.3 4.4 8.0 0.0 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat CaATP_NAI PF12515.3 CAR27526.1 - 0.085 12.3 0.2 2.5 7.6 0.0 2.6 2 0 0 2 2 2 0 Ca2+-ATPase N terminal autoinhibitory domain TPR_21 PF09976.4 CAR27526.1 - 0.2 11.5 7.0 3.9 7.4 0.1 4.6 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.7 CAR27526.1 - 0.7 9.7 4.9 2.5 8.0 0.0 4.2 6 0 0 6 6 6 0 Tetratricopeptide repeat AlaDh_PNT_N PF05222.10 CAR27527.1 - 2.8e-30 105.0 0.0 4e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 CAR27527.1 - 4.5e-15 55.6 0.0 5.9e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain WD40 PF00400.27 CAR27528.1 - 2.2e-28 97.0 1.5 2.6e-09 36.6 0.2 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 CAR27528.1 - 4.1e-06 25.2 0.1 0.00075 17.7 0.1 2.6 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CAR27528.1 - 0.0054 15.5 1.2 7.5 5.1 0.1 3.5 2 1 1 3 3 3 2 Nup133 N terminal like CRT10 PF08728.5 CAR27528.1 - 0.034 12.1 0.0 0.051 11.5 0.0 1.3 1 0 0 1 1 1 0 CRT10 RAB3GAP2_N PF14655.1 CAR27528.1 - 0.059 12.3 0.8 0.33 9.9 0.1 2.4 2 1 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Ank PF00023.25 CAR27529.1 - 1.1e-13 50.2 0.0 8.7e-07 28.4 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 CAR27529.1 - 3.5e-11 43.2 0.0 8.2e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TIG PF01833.19 CAR27529.1 - 2.7e-09 36.8 7.8 3.9e-09 36.3 1.6 2.7 2 0 0 2 2 2 1 IPT/TIG domain Ank_4 PF13637.1 CAR27529.1 - 3e-09 37.1 0.1 2.7e-08 34.0 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CAR27529.1 - 1.8e-07 31.1 0.0 6.7e-06 26.1 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CAR27529.1 - 3.3e-06 26.8 0.0 0.02 15.0 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat PPTA PF01239.17 CAR27530.1 - 5.6e-36 120.4 13.3 1.9e-08 33.3 0.1 5.3 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat ACPS PF01648.15 CAR27530.1 - 0.059 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase superfamily DSPc PF00782.15 CAR27531.1 - 2.4e-25 88.6 0.3 4e-24 84.6 0.2 2.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CAR27531.1 - 0.0046 16.3 0.0 0.011 15.0 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Yippee-Mis18 PF03226.9 CAR27531.1 - 0.055 13.5 0.4 0.23 11.5 0.2 2.0 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Basic PF01586.11 CAR27531.1 - 0.058 14.1 2.0 0.42 11.3 0.1 2.7 3 0 0 3 3 3 0 Myogenic Basic domain Apc15p PF05841.6 CAR27532.1 - 1.1e-30 106.9 10.9 1.1e-30 106.9 7.6 2.4 2 1 1 3 3 3 1 Apc15p protein DUF3578 PF12102.3 CAR27532.1 - 0.063 12.8 1.1 0.3 10.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3578) DUF1748 PF08520.5 CAR27533.1 - 3.7e-19 68.1 0.3 4.9e-19 67.7 0.2 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) WD40 PF00400.27 CAR27534.1 - 4.7e-13 48.4 0.1 4e-05 23.3 0.0 5.3 6 0 0 6 6 6 2 WD domain, G-beta repeat AAA_12 PF13087.1 CAR27535.1 - 6e-59 198.7 0.0 1.3e-58 197.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CAR27535.1 - 2.9e-54 184.1 0.1 5.2e-54 183.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CAR27535.1 - 1.1e-13 50.6 0.0 4e-13 48.9 0.0 1.9 2 0 0 2 2 1 1 Part of AAA domain AAA_30 PF13604.1 CAR27535.1 - 1.4e-10 41.0 0.0 2.6e-08 33.6 0.0 2.6 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 CAR27535.1 - 4e-08 33.0 0.4 0.079 12.4 0.0 3.5 4 0 0 4 4 3 3 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 CAR27535.1 - 1.2e-06 28.0 0.0 0.00028 20.2 0.0 2.0 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain ResIII PF04851.10 CAR27535.1 - 2.8e-05 24.0 0.0 0.00016 21.5 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CAR27535.1 - 9.6e-05 21.9 0.1 0.00064 19.2 0.0 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase Helicase_RecD PF05127.9 CAR27535.1 - 0.0001 22.0 0.0 0.00042 20.0 0.0 2.2 2 1 0 2 2 2 1 Helicase AAA_22 PF13401.1 CAR27535.1 - 0.00011 22.3 0.1 0.00077 19.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain Zot PF05707.7 CAR27535.1 - 0.00014 21.3 0.0 0.00035 20.0 0.0 1.7 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) TrwB_AAD_bind PF10412.4 CAR27535.1 - 0.00057 18.6 0.0 0.0013 17.4 0.0 1.6 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain PhoH PF02562.11 CAR27535.1 - 0.0011 18.2 0.0 0.0039 16.4 0.0 1.9 2 0 0 2 2 2 1 PhoH-like protein AAA_16 PF13191.1 CAR27535.1 - 0.002 18.1 0.0 0.0046 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain PIF1 PF05970.9 CAR27535.1 - 0.0023 16.9 0.0 0.15 11.0 0.0 2.4 2 0 0 2 2 2 1 PIF1-like helicase AAA_14 PF13173.1 CAR27535.1 - 0.003 17.4 0.1 0.12 12.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.4 CAR27535.1 - 0.003 16.5 0.1 0.012 14.6 0.0 2.0 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 CAR27535.1 - 0.0034 16.8 0.0 0.01 15.2 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_10 PF12846.2 CAR27535.1 - 0.0037 16.7 0.0 0.0083 15.5 0.0 1.8 1 1 0 1 1 1 1 AAA-like domain AAA PF00004.24 CAR27535.1 - 0.0056 16.8 0.8 0.024 14.8 0.2 2.5 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 CAR27535.1 - 0.0067 16.7 3.1 1.6 9.0 0.3 3.8 3 1 0 3 3 3 1 AAA domain Flavi_DEAD PF07652.9 CAR27535.1 - 0.0089 15.7 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain MobB PF03205.9 CAR27535.1 - 0.015 15.0 0.0 0.05 13.3 0.0 1.9 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF853 PF05872.7 CAR27535.1 - 0.016 13.5 0.0 0.026 12.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA_17 PF13207.1 CAR27535.1 - 0.018 15.8 0.7 0.25 12.1 0.1 2.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CAR27535.1 - 0.03 13.7 0.0 0.071 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.1 CAR27535.1 - 0.031 14.4 0.0 0.085 12.9 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain CbiA PF01656.18 CAR27535.1 - 0.031 13.6 0.0 0.062 12.6 0.0 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 CAR27535.1 - 0.042 12.6 0.3 0.095 11.4 0.0 1.6 2 0 0 2 2 2 0 ArgK protein NACHT PF05729.7 CAR27535.1 - 0.076 12.6 0.0 0.4 10.3 0.0 2.3 1 0 0 1 1 1 0 NACHT domain FtsK_SpoIIIE PF01580.13 CAR27535.1 - 0.082 12.3 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family GTP_EFTU_D2 PF03144.20 CAR27535.1 - 0.11 12.6 0.5 3 8.0 0.1 2.9 2 0 0 2 2 2 0 Elongation factor Tu domain 2 AAA_33 PF13671.1 CAR27535.1 - 0.13 12.0 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_pol_Rpc82 PF05645.8 CAR27536.1 - 1.2e-62 211.8 0.1 3.1e-62 210.4 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 CAR27536.1 - 9.9e-23 79.7 2.2 9.1e-17 60.6 0.1 3.5 3 0 0 3 3 3 3 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 CAR27536.1 - 0.00015 21.2 0.2 0.51 9.8 0.0 2.9 3 0 0 3 3 3 2 TFIIE alpha subunit TPR_11 PF13414.1 CAR27537.1 - 2e-35 120.2 26.6 8.5e-09 34.9 0.1 11.8 9 2 4 13 13 13 10 TPR repeat TPR_2 PF07719.12 CAR27537.1 - 2.2e-27 92.7 16.8 5.8e-06 25.8 0.0 14.7 14 0 0 14 14 14 5 Tetratricopeptide repeat TPR_19 PF14559.1 CAR27537.1 - 3.3e-26 91.3 9.5 2.2e-05 24.6 0.1 10.8 9 2 2 11 11 11 5 Tetratricopeptide repeat TPR_14 PF13428.1 CAR27537.1 - 2e-25 86.9 2.7 0.0042 17.6 0.0 12.8 7 3 5 12 12 12 5 Tetratricopeptide repeat TPR_16 PF13432.1 CAR27537.1 - 5.3e-24 84.3 2.8 1.8e-05 25.2 0.0 9.5 7 3 3 10 10 8 6 Tetratricopeptide repeat TPR_1 PF00515.23 CAR27537.1 - 4.6e-21 73.4 18.5 3.1e-06 26.5 0.0 13.4 16 0 0 16 16 15 3 Tetratricopeptide repeat Apc3 PF12895.2 CAR27537.1 - 1.4e-17 63.5 17.7 2e-07 31.0 0.1 7.3 7 1 0 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 CAR27537.1 - 4.7e-14 51.3 12.7 0.077 13.2 0.0 11.6 13 0 0 13 13 13 2 Tetratricopeptide repeat TPR_12 PF13424.1 CAR27537.1 - 9e-14 51.1 21.7 0.0021 17.9 0.2 10.6 6 5 5 12 12 12 5 Tetratricopeptide repeat TPR_6 PF13174.1 CAR27537.1 - 2.1e-12 46.5 8.9 0.41 11.1 0.1 10.9 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_8 PF13181.1 CAR27537.1 - 5.3e-10 38.3 27.8 0.00068 19.2 0.0 13.2 15 1 1 16 16 13 1 Tetratricopeptide repeat TPR_7 PF13176.1 CAR27537.1 - 7.7e-08 31.5 5.8 0.15 11.8 0.0 8.7 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_9 PF13371.1 CAR27537.1 - 2.6e-06 27.1 1.5 0.73 9.7 0.0 5.7 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_20 PF14561.1 CAR27537.1 - 4.1e-06 26.8 3.7 4.7 7.4 0.0 6.8 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_4 PF07721.9 CAR27537.1 - 0.0052 17.0 2.7 84 4.0 0.0 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF348 PF03990.9 CAR27537.1 - 0.038 13.5 0.1 0.08 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF348) Fis1_TPR_C PF14853.1 CAR27537.1 - 0.043 13.7 1.8 2.3 8.1 0.0 4.4 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 CAR27537.1 - 0.056 13.6 10.3 4.2 7.5 0.0 5.2 6 0 0 6 6 6 0 Alkyl sulfatase dimerisation EF-hand_7 PF13499.1 CAR27538.1 - 3.1e-11 43.2 0.8 5.6e-09 36.0 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CAR27538.1 - 1.9e-05 24.1 0.8 1.9e-05 24.1 0.6 3.4 4 1 0 4 4 4 1 EF-hand domain EF-hand_8 PF13833.1 CAR27538.1 - 8.6e-05 22.0 2.0 0.0055 16.3 0.0 2.9 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 CAR27538.1 - 0.00016 20.7 0.9 0.00016 20.7 0.6 3.2 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.1 CAR27538.1 - 0.00031 19.9 3.1 0.00031 19.9 2.1 2.0 2 0 0 2 2 2 1 EF hand DUF1456 PF07308.8 CAR27538.1 - 0.025 14.6 0.5 0.56 10.2 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1456) RPAP3_C PF13877.1 CAR27538.1 - 0.038 13.9 0.4 3.6 7.6 0.1 2.9 2 1 0 2 2 2 0 Potential Monad-binding region of RPAP3 IF2_N PF04760.10 CAR27538.1 - 0.19 11.4 0.6 0.6 9.8 0.0 2.2 3 0 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region RNA_pol_Rpb6 PF01192.17 CAR27539.1 - 2.7e-23 81.4 0.3 3.9e-23 80.9 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 zf-C2H2 PF00096.21 CAR27540.1 - 1.1e-23 82.0 58.7 0.0011 19.2 0.1 9.3 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CAR27540.1 - 1.1e-18 66.0 59.6 0.022 15.0 0.1 9.3 9 0 0 9 9 9 9 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CAR27540.1 - 4.2e-12 45.7 69.6 5.2e-05 23.3 0.5 10.0 10 0 0 10 10 10 6 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CAR27540.1 - 4.9e-08 32.8 35.5 0.062 13.4 0.2 8.4 9 0 0 9 9 9 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CAR27540.1 - 2.9e-05 24.1 33.9 0.13 12.5 0.2 8.5 9 0 0 9 9 9 3 Zinc-finger of C2H2 type zf-FCS PF06467.9 CAR27540.1 - 0.15 11.7 0.1 0.15 11.7 0.1 6.4 6 1 1 7 7 7 0 MYM-type Zinc finger with FCS sequence motif DUF2197 PF09963.4 CAR27540.1 - 2.3 8.2 9.6 12 5.9 0.1 4.2 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2197) ATG13 PF10033.4 CAR27541.1 - 2e-62 210.7 0.1 3.3e-62 209.9 0.1 1.4 1 0 0 1 1 1 1 Autophagy-related protein 13 Colicin_C PF12106.3 CAR27541.1 - 3.9 7.1 7.3 0.75 9.4 0.1 2.7 2 0 0 2 2 2 0 Colicin C terminal ribonuclease domain hDGE_amylase PF14701.1 CAR27542.1 - 5.1e-163 542.8 0.1 1.2e-162 541.6 0.0 1.6 2 0 0 2 2 2 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 CAR27542.1 - 2.1e-121 405.1 0.0 3e-121 404.6 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 CAR27542.1 - 2.5e-73 246.4 0.1 5.8e-73 245.2 0.0 1.7 2 0 0 2 2 2 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 CAR27542.1 - 3.9e-22 77.8 0.0 9.1e-22 76.7 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 CAR27542.1 - 8.7e-09 35.1 0.1 0.00012 21.6 0.2 2.3 2 0 0 2 2 2 2 Alpha amylase, catalytic domain Glycos_transf_2 PF00535.21 CAR27543.1 - 1.9e-29 102.4 0.0 2.6e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CAR27543.1 - 1.4e-07 31.5 0.0 1.9e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 CAR27543.1 - 2.2e-06 26.9 0.0 3.1e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 LSM PF01423.17 CAR27544.1 - 4.4e-17 61.3 0.3 5.2e-17 61.1 0.2 1.1 1 0 0 1 1 1 1 LSM domain PIG-U PF06728.8 CAR27545.1 - 1.4e-100 336.9 36.9 1.6e-100 336.6 25.6 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Sec23_trunk PF04811.10 CAR27546.1 - 2e-75 253.2 0.0 2.9e-75 252.7 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CAR27546.1 - 2.1e-35 120.2 0.1 4.9e-35 119.0 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 CAR27546.1 - 8.4e-29 99.9 0.1 1.9e-28 98.8 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 CAR27546.1 - 1.3e-13 50.2 9.3 2.3e-13 49.4 6.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 CAR27546.1 - 1.9e-10 40.2 0.0 4.1e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat zf-MIZ PF02891.15 CAR27546.1 - 0.02 14.3 1.3 0.041 13.4 0.9 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger ThiF PF00899.16 CAR27547.1 - 4.1e-20 71.9 0.0 8.7e-20 70.9 0.0 1.5 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 CAR27547.1 - 0.044 13.8 0.0 0.09 12.8 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HDA2-3 PF11496.3 CAR27548.1 - 3.7e-84 282.0 0.4 3.7e-84 282.0 0.3 1.8 2 1 1 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 WD40 PF00400.27 CAR27549.1 - 8.6e-52 171.2 9.7 9.3e-14 50.6 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nbas_N PF15492.1 CAR27549.1 - 0.0059 15.7 0.1 0.07 12.2 0.0 2.4 3 1 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 CAR27549.1 - 0.013 13.8 0.0 0.053 11.8 0.0 1.8 2 0 0 2 2 2 0 Cytochrome D1 heme domain AbrB-like PF14250.1 CAR27549.1 - 0.083 12.8 0.0 4.2 7.3 0.0 2.6 2 0 0 2 2 2 0 AbrB-like transcriptional regulator Prenyltrans PF00432.16 CAR27550.1 - 1.2e-61 203.8 4.9 1.6e-13 49.9 0.1 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CAR27550.1 - 9.8e-29 100.0 0.0 2.9e-12 47.0 0.0 3.9 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 CAR27550.1 - 2.7e-09 36.9 0.0 0.0003 20.7 0.0 3.1 1 1 2 3 3 3 3 Prenyltransferase-like A2M_comp PF07678.9 CAR27550.1 - 0.00037 19.7 0.0 0.032 13.4 0.0 3.3 3 1 0 4 4 4 1 A-macroglobulin complement component DUF4576 PF15144.1 CAR27550.1 - 0.091 12.4 0.0 6.4 6.4 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4576) DNA_pol_E_B PF04042.11 CAR27551.1 - 7.1e-53 178.9 1.2 1.1e-52 178.3 0.8 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DUF4047 PF13256.1 CAR27551.1 - 0.0058 16.5 0.5 0.0058 16.5 0.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4047) NBP1 PF08537.5 CAR27552.1 - 1.9e-103 346.0 12.0 2.2e-103 345.8 8.3 1.0 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 IncA PF04156.9 CAR27552.1 - 0.0011 18.6 4.1 0.0018 17.9 2.8 1.4 1 0 0 1 1 1 1 IncA protein ING PF12998.2 CAR27552.1 - 0.032 14.5 2.3 0.036 14.3 0.3 2.2 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Golgin_A5 PF09787.4 CAR27552.1 - 0.06 11.8 7.4 0.47 8.9 0.1 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 Macoilin PF09726.4 CAR27552.1 - 0.41 8.8 6.7 0.34 9.1 3.9 1.3 1 1 0 1 1 1 0 Transmembrane protein AAA PF00004.24 CAR27553.1 - 2.1e-43 147.6 0.0 3.6e-43 146.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 CAR27553.1 - 1.2e-28 98.7 0.0 1.1e-27 95.7 0.0 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 CAR27553.1 - 9.2e-22 76.7 2.0 9.2e-22 76.7 1.4 2.5 3 0 0 3 3 2 1 MIT (microtubule interacting and transport) domain AAA_22 PF13401.1 CAR27553.1 - 2e-06 27.9 0.1 0.001 19.2 0.1 3.3 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CAR27553.1 - 2.8e-06 28.1 0.0 1.5e-05 25.7 0.0 2.2 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 CAR27553.1 - 8.8e-06 25.4 0.0 5.4e-05 22.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 CAR27553.1 - 1.7e-05 24.2 0.0 7e-05 22.3 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein RuvB_N PF05496.7 CAR27553.1 - 2e-05 23.7 0.0 3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CAR27553.1 - 2.4e-05 24.2 0.1 8e-05 22.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 CAR27553.1 - 2.5e-05 24.3 0.1 0.00018 21.5 0.0 2.3 2 1 0 2 2 1 1 AAA ATPase domain AAA_25 PF13481.1 CAR27553.1 - 2.5e-05 23.7 0.1 0.035 13.5 0.0 2.4 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.8 CAR27553.1 - 2.7e-05 23.2 0.0 9.9e-05 21.3 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.17 CAR27553.1 - 0.00023 21.3 0.0 0.0074 16.4 0.0 2.5 2 0 0 2 2 2 1 RNA helicase TIP49 PF06068.8 CAR27553.1 - 0.00024 19.9 0.0 0.00039 19.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_2 PF07724.9 CAR27553.1 - 0.00055 19.8 0.1 0.0018 18.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 CAR27553.1 - 0.00057 19.7 0.0 0.0017 18.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 CAR27553.1 - 0.0059 16.9 0.0 0.019 15.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CAR27553.1 - 0.0072 15.4 1.7 0.11 11.5 0.0 2.9 3 1 0 3 3 2 1 Zeta toxin AAA_24 PF13479.1 CAR27553.1 - 0.013 15.0 0.0 0.029 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CAR27553.1 - 0.021 14.5 0.0 0.053 13.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 CAR27553.1 - 0.027 13.6 0.0 0.063 12.4 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 CAR27553.1 - 0.032 13.3 0.1 4.1 6.4 0.0 2.4 1 1 1 2 2 2 0 KaiC PhoH PF02562.11 CAR27553.1 - 0.033 13.4 0.0 0.063 12.5 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Torsin PF06309.6 CAR27553.1 - 0.037 13.9 0.0 0.079 12.8 0.0 1.5 1 0 0 1 1 1 0 Torsin NACHT PF05729.7 CAR27553.1 - 0.041 13.5 0.0 0.62 9.7 0.0 2.3 1 1 1 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 CAR27553.1 - 0.06 13.0 1.9 0.43 10.2 0.0 2.6 2 1 1 3 3 3 0 Archaeal ATPase ResIII PF04851.10 CAR27553.1 - 0.068 12.9 0.1 0.72 9.6 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.12 CAR27553.1 - 0.08 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.1 CAR27553.1 - 0.086 12.7 0.0 0.28 11.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain Sigma54_activat PF00158.21 CAR27553.1 - 0.11 12.0 0.0 0.28 10.6 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 CAR27553.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_21 PF13304.1 CAR27553.1 - 0.17 11.7 2.1 2.3 8.1 0.0 2.7 2 1 1 3 3 3 0 AAA domain Pyridox_oxidase PF01243.15 CAR27554.1 - 1.3e-16 60.3 0.0 6e-16 58.2 0.0 1.9 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyrid_oxidase_2 PF13883.1 CAR27554.1 - 0.017 14.9 0.3 0.042 13.6 0.2 1.6 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase PWWP PF00855.12 CAR27555.1 - 6e-17 61.6 0.1 6e-17 61.6 0.0 2.3 2 1 0 2 2 2 1 PWWP domain TIMELESS PF04821.9 CAR27555.1 - 0.0025 17.1 0.5 0.0025 17.1 0.3 2.3 2 1 0 2 2 2 1 Timeless protein DUF4348 PF14254.1 CAR27555.1 - 0.041 12.9 0.1 0.041 12.9 0.1 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4348) Hid1 PF12722.2 CAR27555.1 - 1.1 6.8 14.5 1.3 6.6 10.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ndc1_Nup PF09531.5 CAR27555.1 - 3.1 6.1 6.5 3.6 5.8 4.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MASE1 PF05231.9 CAR27557.1 - 0.018 14.1 0.2 0.02 13.9 0.1 1.1 1 0 0 1 1 1 0 MASE1 ABC2_membrane_4 PF12730.2 CAR27557.1 - 0.024 13.8 0.8 0.031 13.4 0.6 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein WD40 PF00400.27 CAR27558.1 - 5.6e-05 22.8 0.3 0.021 14.6 0.0 4.1 5 0 0 5 5 5 1 WD domain, G-beta repeat PQQ_3 PF13570.1 CAR27558.1 - 0.01 16.0 0.4 1.9 8.8 0.0 4.1 5 0 0 5 5 5 0 PQQ-like domain BUD22 PF09073.5 CAR27558.1 - 6.8 5.6 32.0 0.94 8.4 19.0 1.7 2 0 0 2 2 2 0 BUD22 Med10 PF09748.4 CAR27559.1 - 5.5e-45 152.3 0.7 6.6e-45 152.0 0.5 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex D123 PF07065.9 CAR27559.1 - 0.019 14.0 0.2 0.047 12.7 0.0 1.6 2 0 0 2 2 2 0 D123 PBS_linker_poly PF00427.16 CAR27559.1 - 0.066 12.8 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide NPV_P10 PF05531.7 CAR27559.1 - 0.28 11.4 3.3 1.4 9.1 0.1 2.8 2 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein PAPS_reduct PF01507.14 CAR27560.1 - 2.1e-38 131.8 0.0 2.6e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Ribosomal_S14 PF00253.16 CAR27561.1 - 2.2e-18 65.3 0.3 4.1e-18 64.4 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Ras PF00071.17 CAR27562.1 - 3.9e-54 182.3 0.0 5.8e-54 181.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR27562.1 - 1.7e-16 60.7 0.0 4.3e-16 59.4 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CAR27562.1 - 4.1e-07 29.4 0.0 9.5e-07 28.2 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CAR27562.1 - 0.00022 20.7 0.1 0.0014 18.0 0.0 2.1 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CAR27562.1 - 0.035 13.2 0.1 0.055 12.6 0.0 1.5 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region U79_P34 PF03064.11 CAR27562.1 - 0.15 11.5 4.3 0.22 10.9 2.9 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Ras PF00071.17 CAR27563.1 - 4.7e-55 185.4 0.0 5.5e-55 185.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR27563.1 - 5.8e-16 59.0 0.0 9.4e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAR27563.1 - 4.5e-07 29.2 0.0 6.3e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CAR27563.1 - 0.0022 17.4 0.0 0.0099 15.3 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CAR27563.1 - 0.013 14.6 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CAR27563.1 - 0.08 12.1 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NLBH PF05211.7 CAR27564.1 - 0.013 14.8 0.1 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 Neuraminyllactose-binding hemagglutinin precursor (NLBH) Fmp27 PF10344.4 CAR27565.1 - 3.7e-123 412.0 21.0 7.3e-123 411.0 14.6 1.5 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Fmp27_WPPW PF10359.4 CAR27565.1 - 1.4e-96 323.8 6.1 2.3e-96 323.0 4.3 1.4 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.4 CAR27565.1 - 3.8e-79 266.6 2.9 2.7e-76 257.2 2.0 2.6 1 1 0 1 1 1 1 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.4 CAR27565.1 - 1.6e-52 177.5 0.0 1.5e-51 174.3 0.0 2.5 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 CAR27565.1 - 5.8e-52 175.6 2.2 1.8e-51 173.9 1.6 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 CAR27565.1 - 3e-33 114.3 0.7 9.6e-32 109.4 0.0 3.9 4 0 0 4 4 4 1 RNA pol II promoter Fmp27 protein domain RRM_6 PF14259.1 CAR27566.1 - 1.5e-10 40.8 0.0 2.9e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAR27566.1 - 0.0089 15.6 0.0 0.023 14.3 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR27566.1 - 0.064 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ORC4_C PF14629.1 CAR27567.1 - 1.1e-34 119.5 1.2 2.1e-34 118.6 0.5 1.7 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 CAR27567.1 - 8.5e-08 32.3 0.0 1.8e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CAR27567.1 - 1.9e-06 28.0 0.0 4.7e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 CAR27567.1 - 7.1e-05 22.6 0.2 0.00017 21.3 0.2 1.6 1 0 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 CAR27567.1 - 0.0022 17.6 0.0 0.0058 16.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA PF00004.24 CAR27567.1 - 0.0038 17.4 0.1 0.046 13.9 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 CAR27567.1 - 0.01 14.7 0.0 0.017 13.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Pkinase PF00069.20 CAR27568.1 - 2.7e-70 236.4 0.0 3.7e-70 236.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR27568.1 - 8e-28 97.2 0.0 7.2e-27 94.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 CAR27568.1 - 0.011 14.5 0.3 0.018 13.8 0.2 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.1 CAR27568.1 - 0.21 10.4 0.1 0.48 9.3 0.0 1.6 1 1 0 1 1 1 0 Kinase-like RGS PF00615.14 CAR27569.1 - 9.2e-18 64.4 0.0 1.2e-15 57.6 0.0 2.8 1 1 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 CAR27569.1 - 1.8e-09 37.1 0.2 6.4e-09 35.4 0.0 2.1 3 0 0 3 3 3 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) MAM33 PF02330.11 CAR27569.1 - 0.011 15.5 0.1 0.037 13.7 0.1 1.9 1 0 0 1 1 1 0 Mitochondrial glycoprotein GTP_EFTU PF00009.22 CAR27570.1 - 1.8e-38 131.9 0.0 3.2e-38 131.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 CAR27570.1 - 2.5e-35 120.3 0.2 5.7e-35 119.2 0.1 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 CAR27570.1 - 1.6e-11 44.1 0.6 5.4e-11 42.4 0.4 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CAR27570.1 - 0.0079 16.1 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CAR27570.1 - 0.041 13.7 0.5 0.83 9.4 0.0 3.1 4 0 0 4 4 4 0 Dynamin family Notch PF00066.12 CAR27570.1 - 3.4 7.9 5.7 6.7 7.0 4.0 1.5 1 0 0 1 1 1 0 LNR domain Zn_clus PF00172.13 CAR27571.1 - 1.5e-08 34.4 10.9 2.6e-08 33.6 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DCP2 PF05026.8 CAR27571.1 - 0.024 14.5 0.1 0.081 12.8 0.1 2.0 1 0 0 1 1 1 0 Dcp2, box A domain DUF4629 PF15442.1 CAR27571.1 - 0.2 11.7 3.7 0.55 10.3 2.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) MFS_1 PF07690.11 CAR27572.1 - 2.2e-30 105.5 26.8 4.8e-18 64.9 3.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CAR27572.1 - 7.5e-17 60.8 19.5 4.2e-10 38.6 4.5 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 CAR27572.1 - 2.1e-07 29.9 17.4 4e-07 28.9 12.1 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter ATG22 PF11700.3 CAR27572.1 - 1.7e-06 26.7 8.6 1.7e-06 26.7 6.0 2.8 2 1 1 3 3 3 1 Vacuole effluxer Atg22 like MFS_1_like PF12832.2 CAR27572.1 - 0.04 13.7 0.6 0.04 13.7 0.4 3.7 5 0 0 5 5 5 0 MFS_1 like family MFS_3 PF05977.8 CAR27572.1 - 2.6 6.0 11.7 0.066 11.3 1.6 2.5 2 2 0 2 2 2 0 Transmembrane secretion effector Carn_acyltransf PF00755.15 CAR27573.1 - 7e-68 229.1 0.0 3.1e-56 190.6 0.0 2.1 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase Ribosomal_S7 PF00177.16 CAR27574.1 - 7.5e-39 132.6 0.8 9.9e-39 132.2 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e GCV_T PF01571.16 CAR27575.1 - 6.1e-06 25.7 0.0 0.4 9.9 0.0 3.2 3 0 0 3 3 3 3 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 CAR27575.1 - 0.0022 18.0 0.0 0.0062 16.5 0.0 1.9 1 1 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain ATP-synt_ab PF00006.20 CAR27576.1 - 2.7e-62 210.0 0.0 4.2e-62 209.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CAR27576.1 - 4.3e-25 88.3 0.3 7.5e-25 87.6 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CAR27576.1 - 5e-25 87.5 0.8 1.4e-24 86.0 0.5 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain KaiC PF06745.8 CAR27576.1 - 0.0041 16.2 0.2 0.007 15.5 0.1 1.4 1 0 0 1 1 1 1 KaiC DUF258 PF03193.11 CAR27576.1 - 0.012 14.8 0.1 0.021 14.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 CAR27576.1 - 0.016 14.9 0.2 0.85 9.3 0.0 3.0 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 CAR27576.1 - 0.021 14.4 0.1 0.059 13.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA PF00004.24 CAR27576.1 - 0.025 14.7 0.1 0.76 9.9 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 CAR27576.1 - 0.038 13.4 0.1 0.13 11.6 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 CAR27576.1 - 0.04 13.8 0.1 0.14 12.1 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain Arch_ATPase PF01637.13 CAR27576.1 - 0.06 13.0 0.0 0.15 11.6 0.0 1.6 2 0 0 2 2 2 0 Archaeal ATPase AAA_22 PF13401.1 CAR27576.1 - 0.066 13.3 0.0 0.21 11.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 CAR27576.1 - 0.079 11.8 0.8 0.37 9.5 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.17 CAR27576.1 - 0.093 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase P5CR_dimer PF14748.1 CAR27577.1 - 2e-32 111.3 0.4 4.2e-32 110.3 0.2 1.6 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 CAR27577.1 - 4.3e-06 27.0 0.5 1.4e-05 25.4 0.3 1.9 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 CAR27577.1 - 8.1e-05 22.1 0.3 0.00016 21.1 0.2 1.6 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Caps_synth_GfcC PF06251.6 CAR27577.1 - 0.022 13.9 0.1 0.042 12.9 0.1 1.5 1 0 0 1 1 1 0 Capsule biosynthesis GfcC NAD_binding_2 PF03446.10 CAR27577.1 - 0.025 14.4 0.0 0.99 9.2 0.0 2.3 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.17 CAR27577.1 - 0.069 13.6 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold JmjC PF02373.17 CAR27578.1 - 2.2e-40 137.4 0.4 5.4e-40 136.1 0.3 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 CAR27578.1 - 9.6e-14 50.8 3.7 9.6e-14 50.8 2.6 2.4 2 0 0 2 2 2 1 PHD-finger JmjN PF02375.12 CAR27578.1 - 8.3e-09 34.8 0.5 1.9e-08 33.6 0.0 1.9 2 0 0 2 2 2 1 jmjN domain PHD_2 PF13831.1 CAR27578.1 - 0.0089 15.3 2.0 0.023 13.9 0.1 2.5 2 0 0 2 2 2 1 PHD-finger DUF4047 PF13256.1 CAR27578.1 - 0.036 14.0 0.4 0.12 12.3 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) HBS1_N PF08938.5 CAR27578.1 - 0.54 10.4 0.0 0.54 10.4 0.0 3.7 4 0 0 4 4 4 0 HBS1 N-terminus Prok-RING_1 PF14446.1 CAR27578.1 - 0.94 9.2 9.1 0.054 13.2 1.0 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Ilm1 PF10311.4 CAR27579.1 - 1.7e-40 138.2 8.7 2.2e-40 137.8 6.1 1.2 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 DUF2301 PF10063.4 CAR27579.1 - 1.7 8.8 6.6 0.48 10.6 2.0 1.8 2 0 0 2 2 2 0 Uncharacterized integral membrane protein (DUF2301) Med17 PF10156.4 CAR27580.1 - 1.3e-142 475.4 13.5 1.7e-142 474.9 9.4 1.2 1 0 0 1 1 1 1 Subunit 17 of Mediator complex PCI PF01399.22 CAR27581.1 - 1.1e-20 73.8 0.4 3.4e-20 72.3 0.3 1.8 1 0 0 1 1 1 1 PCI domain Rpn3_C PF08375.6 CAR27581.1 - 2.5e-20 72.6 2.2 5.8e-20 71.4 1.5 1.7 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal FeoC PF09012.5 CAR27581.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 FeoC like transcriptional regulator Peptidase_M48 PF01435.13 CAR27582.1 - 1.1e-47 162.5 0.0 1.5e-47 162.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 DUF2268 PF10026.4 CAR27582.1 - 0.0072 15.7 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Predicted Zn-dependent protease (DUF2268) DUF2201_N PF13203.1 CAR27582.1 - 0.16 11.0 0.1 0.3 10.2 0.1 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain TRAM_LAG1_CLN8 PF03798.11 CAR27583.1 - 1.6e-27 96.3 18.2 1.6e-27 96.3 12.6 1.7 2 0 0 2 2 2 1 TLC domain PfkB PF00294.19 CAR27584.1 - 1.3e-68 231.4 1.0 1.5e-68 231.1 0.7 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 CAR27584.1 - 0.00018 20.7 0.0 0.00041 19.6 0.0 1.5 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Na_Ca_ex PF01699.19 CAR27585.1 - 7.5e-51 171.4 24.3 6.2e-30 103.6 4.8 2.6 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Exo_endo_phos_2 PF14529.1 CAR27585.1 - 0.017 14.7 0.1 0.038 13.6 0.1 1.5 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase HemY_N PF07219.8 CAR27585.1 - 0.42 10.1 0.0 0.42 10.1 0.0 2.7 4 0 0 4 4 4 0 HemY protein N-terminus Lipase_3 PF01764.20 CAR27586.1 - 1.5e-36 125.1 0.0 2.5e-36 124.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.15 CAR27586.1 - 0.04 14.1 0.0 0.051 13.7 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.15 CAR27586.1 - 0.12 11.8 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase G-alpha PF00503.15 CAR27587.1 - 9.4e-120 399.8 3.6 1.1e-119 399.6 2.5 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CAR27587.1 - 5e-15 55.1 0.4 2.7e-10 39.7 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CAR27587.1 - 2.8e-05 23.3 1.5 0.016 14.3 0.3 2.8 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region Miro PF08477.8 CAR27587.1 - 8.9e-05 22.9 0.3 0.07 13.6 0.1 3.0 1 1 2 3 3 3 2 Miro-like protein AAA_29 PF13555.1 CAR27587.1 - 0.023 14.1 0.1 0.054 13.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 CAR27587.1 - 0.049 13.0 0.0 1.4 8.2 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CAR27587.1 - 0.065 13.1 0.1 0.9 9.5 0.1 2.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Pox_Ag35 PF03286.9 CAR27587.1 - 0.34 10.4 3.1 0.19 11.2 0.8 1.5 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Pam17 PF08566.5 CAR27588.1 - 4.3e-71 238.1 0.0 4.8e-71 238.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Pmp3 PF01679.12 CAR27589.1 - 2.9e-17 62.1 5.1 3.5e-17 61.8 3.5 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator PRCH PF03967.8 CAR27589.1 - 0.12 11.9 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region F-box-like PF12937.2 CAR27590.1 - 4.6e-07 29.4 0.4 2.3e-06 27.2 0.1 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CAR27590.1 - 0.00021 20.8 0.8 0.00069 19.2 0.2 2.3 2 0 0 2 2 2 1 F-box domain Zn_clus PF00172.13 CAR27591.1 - 4.2e-08 32.9 12.8 7.8e-08 32.1 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Las1 PF04031.8 CAR27592.1 - 1.5e-53 180.5 3.3 1.8e-53 180.3 0.2 2.3 2 0 0 2 2 2 1 Las1-like Retrotrans_gag PF03732.12 CAR27592.1 - 0.21 11.7 13.3 0.88 9.6 0.4 3.6 2 2 1 3 3 3 0 Retrotransposon gag protein RNA_polI_A34 PF08208.6 CAR27593.1 - 6.3e-35 120.6 12.8 6.3e-35 120.6 8.9 1.5 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 Zip PF02535.17 CAR27593.1 - 0.61 9.0 2.5 0.51 9.2 1.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Med19 PF10278.4 CAR27593.1 - 9.7 5.8 19.4 0.68 9.5 10.1 1.6 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 TFIIE_beta PF02186.10 CAR27594.1 - 1.2e-20 73.2 0.9 2.4e-20 72.2 0.6 1.6 1 0 0 1 1 1 1 TFIIE beta subunit core domain DUF1987 PF09345.5 CAR27594.1 - 0.014 15.1 0.2 0.029 14.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1987) Glyco_hydro_70 PF02324.11 CAR27595.1 - 0.0098 13.7 0.7 0.017 12.9 0.3 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 70 Neural_ProG_Cyt PF06567.6 CAR27595.1 - 0.039 14.0 0.1 0.094 12.8 0.0 1.6 1 0 0 1 1 1 0 Neural chondroitin sulphate proteoglycan cytoplasmic domain CRAL_TRIO PF00650.15 CAR27597.1 - 2.5e-26 92.0 0.7 5.3e-26 91.0 0.2 1.7 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CAR27597.1 - 1.5e-05 25.0 1.3 4.5e-05 23.4 0.9 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain RAMP PF04901.8 CAR27597.1 - 0.15 11.8 0.9 0.67 9.7 0.1 2.1 2 0 0 2 2 2 0 Receptor activity modifying family BATS PF06968.8 CAR27598.1 - 3.3e-27 94.1 0.0 7.6e-27 92.9 0.0 1.6 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 CAR27598.1 - 3.7e-16 59.7 0.1 1.3e-15 57.9 0.1 1.8 2 0 0 2 2 2 1 Radical SAM superfamily DUF713 PF05218.9 CAR27599.1 - 0.002 17.8 0.6 0.002 17.8 0.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF713) DUF1673 PF07895.6 CAR27599.1 - 0.34 10.4 4.1 0.53 9.7 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) Ank_2 PF12796.2 CAR27600.1 - 1.2e-41 140.8 0.8 3.8e-17 62.3 0.3 3.6 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 CAR27600.1 - 1.6e-34 115.9 4.2 2.1e-11 43.0 0.5 5.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 CAR27600.1 - 2e-30 104.0 4.6 2.4e-08 33.9 0.4 4.9 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 CAR27600.1 - 2.9e-28 97.7 1.2 1.1e-12 48.1 0.1 5.0 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CAR27600.1 - 1.5e-23 80.5 0.1 4e-08 32.7 0.3 5.8 5 0 0 5 5 5 4 Ankyrin repeat COX4 PF02936.9 CAR27601.1 - 3.5e-42 143.4 0.1 3.9e-42 143.3 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1289 PF06945.8 CAR27601.1 - 0.13 11.7 2.1 2.5 7.6 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1289) Methyltransf_16 PF10294.4 CAR27602.1 - 0.0063 15.9 0.1 0.14 11.5 0.0 2.3 1 1 0 2 2 2 2 Putative methyltransferase COG5 PF10392.4 CAR27603.1 - 2.4e-38 131.0 1.4 2.4e-38 131.0 0.9 3.4 2 1 2 4 4 4 1 Golgi transport complex subunit 5 CorA PF01544.13 CAR27603.1 - 0.025 13.6 7.7 0.015 14.3 3.1 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF2011 PF09428.5 CAR27604.1 - 9.6e-36 122.5 11.7 1.3e-35 122.1 8.1 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) Sec23_trunk PF04811.10 CAR27605.1 - 1.4e-69 234.2 0.1 4.5e-69 232.4 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CAR27605.1 - 3.5e-23 81.0 0.8 9.4e-23 79.6 0.1 2.1 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 CAR27605.1 - 7.2e-17 60.6 6.6 1.3e-16 59.8 4.6 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 CAR27605.1 - 2.7e-13 50.2 0.2 7.8e-13 48.7 0.1 1.9 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 CAR27605.1 - 2.8e-10 39.7 0.0 6.5e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat P30 PF07390.6 CAR27605.1 - 0.059 12.8 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Mycoplasma P30 protein Metallopep PF12044.3 CAR27606.1 - 3.5e-166 552.8 0.0 4.1e-166 552.6 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 CAR27606.1 - 6e-05 22.9 0.1 0.001 18.9 0.0 2.3 1 1 1 2 2 2 1 Jacalin-like lectin domain Reprolysin_5 PF13688.1 CAR27606.1 - 0.024 14.5 0.1 0.043 13.7 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 CAR27606.1 - 0.028 14.9 0.4 0.064 13.7 0.1 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like 6PF2K PF01591.13 CAR27607.1 - 5.8e-81 270.8 0.0 5.8e-81 270.8 0.0 2.0 2 0 0 2 2 2 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CAR27607.1 - 7.3e-28 97.6 0.5 2.7e-26 92.5 0.0 3.0 2 1 1 3 3 3 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 CAR27607.1 - 8.9e-11 41.8 0.0 3.5e-10 39.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CAR27607.1 - 5.4e-09 36.9 0.0 3.4e-08 34.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 CAR27607.1 - 0.00034 20.5 0.1 0.0059 16.5 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 CAR27607.1 - 0.00052 19.1 0.0 0.001 18.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 CAR27607.1 - 0.0018 18.5 0.0 0.0018 18.5 0.0 3.5 4 1 0 4 4 4 1 AAA domain APS_kinase PF01583.15 CAR27607.1 - 0.0062 16.2 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase KTI12 PF08433.5 CAR27607.1 - 0.011 14.9 0.0 0.011 14.9 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Ribosomal_S6 PF01250.12 CAR27607.1 - 0.07 12.9 0.1 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S6 Menin PF05053.8 CAR27607.1 - 4.5 5.3 8.7 8.6 4.3 6.0 1.4 1 0 0 1 1 1 0 Menin Mob1_phocein PF03637.12 CAR27608.1 - 2.4e-74 248.7 0.9 6.2e-74 247.4 0.5 1.6 2 0 0 2 2 2 1 Mob1/phocein family Glycos_transf_1 PF00534.15 CAR27609.1 - 1e-13 51.0 0.0 2.6e-13 49.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CAR27609.1 - 0.021 14.9 0.0 0.064 13.4 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 CAR27609.1 - 0.045 13.4 0.0 0.094 12.4 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 PH PF00169.24 CAR27610.1 - 5.7e-16 58.6 0.1 1.9e-15 56.9 0.1 2.0 1 0 0 1 1 1 1 PH domain Peptidase_M1 PF01433.15 CAR27611.1 - 6.1e-79 265.8 0.0 9e-79 265.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 CAR27611.1 - 2.3e-44 150.4 0.0 4.5e-44 149.5 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 CAR27611.1 - 2.7e-15 56.5 0.0 4.8e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 CAR27611.1 - 0.24 11.3 2.0 1.4 8.8 1.4 2.2 1 1 0 1 1 1 0 M61 glycyl aminopeptidase PRA1 PF03208.14 CAR27612.1 - 5.2e-40 136.3 1.7 6.1e-40 136.0 1.1 1.1 1 0 0 1 1 1 1 PRA1 family protein IncA PF04156.9 CAR27612.1 - 0.32 10.5 0.1 0.32 10.5 0.1 2.5 3 0 0 3 3 3 0 IncA protein Tic20 PF09685.5 CAR27612.1 - 0.68 9.9 7.4 0.13 12.2 0.2 2.1 1 1 1 2 2 2 0 Tic20-like protein Adeno_E3B PF03376.9 CAR27612.1 - 1.6 8.6 3.9 19 5.2 0.3 2.3 1 1 1 2 2 2 0 Adenovirus E3B protein DUF2722 PF10846.3 CAR27613.1 - 2.1e-48 165.3 42.5 4.5e-48 164.3 29.5 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2722) SHQ1 PF04925.10 CAR27614.1 - 4.7e-71 238.1 0.7 6.9e-71 237.6 0.5 1.2 1 0 0 1 1 1 1 SHQ1 protein Diphthamide_syn PF01866.12 CAR27615.1 - 2.6e-113 378.3 0.0 3.5e-113 377.9 0.0 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein COG6 PF06419.6 CAR27616.1 - 1.1e-147 492.8 24.3 1.6e-147 492.3 16.8 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Pro_CA PF00484.14 CAR27618.1 - 5.9e-37 127.0 0.2 7.4e-37 126.7 0.2 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Erp_C PF06780.6 CAR27618.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Erp protein C-terminus Glyco_hydro_15 PF00723.16 CAR27619.1 - 3.5e-59 200.5 0.0 4.9e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Complex1_LYR_2 PF13233.1 CAR27620.1 - 5.7e-21 74.9 4.3 7.5e-21 74.5 3.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like ETF_QO PF05187.8 CAR27620.1 - 0.022 14.7 0.1 0.032 14.2 0.1 1.3 1 0 0 1 1 1 0 Electron transfer flavoprotein-ubiquinone oxidoreductase DUF3584 PF12128.3 CAR27620.1 - 0.055 10.8 7.3 0.062 10.6 5.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NusB PF01029.13 CAR27620.1 - 0.11 12.4 2.8 0.16 11.9 1.5 1.7 1 1 1 2 2 2 0 NusB family Pox_polyA_pol_C PF12629.2 CAR27620.1 - 0.21 11.2 2.2 0.26 10.9 1.5 1.1 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase C-terminal domain Aldo_ket_red PF00248.16 CAR27621.1 - 3e-63 213.3 0.0 3.3e-63 213.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Iso_dh PF00180.15 CAR27622.1 - 6.4e-76 255.5 0.4 8.1e-76 255.2 0.3 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase CLTH PF10607.4 CAR27623.1 - 2.1e-28 98.8 0.4 2.1e-28 98.8 0.2 2.4 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain V_ATPase_I PF01496.14 CAR27623.1 - 0.0072 14.2 2.4 0.01 13.7 1.6 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF1132 PF06575.7 CAR27623.1 - 0.012 15.9 1.1 0.28 11.4 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1132) Snapin_Pallidin PF14712.1 CAR27623.1 - 0.031 14.5 1.8 0.086 13.1 1.2 1.9 1 1 0 1 1 1 0 Snapin/Pallidin TPR_1 PF00515.23 CAR27623.1 - 0.069 12.7 0.1 0.16 11.5 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4559 PF15112.1 CAR27623.1 - 0.53 9.3 4.7 1.2 8.1 3.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DUF2431 PF10354.4 CAR27624.1 - 6.6e-59 198.5 0.2 1e-58 198.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) DUF3043 PF11241.3 CAR27624.1 - 0.33 10.5 2.9 0.69 9.4 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) PIG-H PF10181.4 CAR27625.1 - 3.6e-14 52.1 0.2 9.1e-14 50.8 0.1 1.7 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Myb_DNA-binding PF00249.26 CAR27626.1 - 2.8e-07 30.4 0.0 7.9e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CAR27626.1 - 0.0013 18.8 0.1 0.0047 17.0 0.1 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain K_oxygenase PF13434.1 CAR27626.1 - 0.19 10.6 2.3 2.4 6.9 0.1 2.5 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) PspB PF06667.7 CAR27626.1 - 2 8.4 4.1 4.1 7.4 2.2 2.1 2 0 0 2 2 2 0 Phage shock protein B Tim17 PF02466.14 CAR27627.1 - 9.4e-33 112.9 5.1 1.1e-32 112.7 3.5 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Pkinase PF00069.20 CAR27628.1 - 2.1e-50 171.3 0.0 1.5e-49 168.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR27628.1 - 4.5e-23 81.6 0.0 1.1e-22 80.4 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CAR27628.1 - 0.0037 17.0 0.0 0.0037 17.0 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CAR27628.1 - 0.021 14.1 0.0 0.021 14.1 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Activator_LAG-3 PF11498.3 CAR27628.1 - 0.056 12.2 30.2 2.9 6.5 19.3 2.2 1 1 1 2 2 2 0 Transcriptional activator LAG-3 Choline_kinase PF01633.15 CAR27628.1 - 0.18 11.3 0.0 0.18 11.3 0.0 2.5 3 1 1 4 4 4 0 Choline/ethanolamine kinase RNA_pol_Rpb4 PF03874.11 CAR27629.1 - 3.6e-36 123.7 6.7 8.8e-36 122.4 4.7 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb4 Tom37_C PF11801.3 CAR27629.1 - 0.0069 16.2 1.0 0.0069 16.2 0.7 1.4 2 0 0 2 2 2 1 Tom37 C-terminal domain Glyco_transf_15 PF01793.11 CAR27630.1 - 4.2e-135 449.9 13.9 5.3e-135 449.6 9.6 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ribosomal_L1 PF00687.16 CAR27631.1 - 1.2e-46 158.8 1.4 1.4e-46 158.5 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DEAD PF00270.24 CAR27632.1 - 1.9e-42 144.6 2.0 3.2e-42 143.8 0.4 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR27632.1 - 1.4e-27 95.3 0.2 1.1e-26 92.4 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAR27632.1 - 3.4e-06 27.0 0.4 6.6e-06 26.0 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 CAR27632.1 - 0.0049 16.4 0.0 0.38 10.3 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CAR27632.1 - 0.011 15.4 0.1 0.062 13.0 0.1 2.1 2 0 0 2 2 2 0 Part of AAA domain Helicase_C_2 PF13307.1 CAR27632.1 - 0.041 13.8 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain DUF1811 PF08838.5 CAR27632.1 - 0.082 12.8 0.0 8.8 6.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) SNF2_N PF00176.18 CAR27632.1 - 0.12 11.1 0.0 0.16 10.7 0.0 1.3 1 1 0 1 1 1 0 SNF2 family N-terminal domain Glyco_transf_8 PF01501.15 CAR27633.1 - 1.8e-35 122.4 0.0 2.5e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Ribosomal_S21e PF01249.13 CAR27634.1 - 1.3e-39 134.0 0.0 1.4e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e tRNA_U5-meth_tr PF05958.6 CAR27635.1 - 1.6e-21 76.4 0.2 1.9e-20 72.8 0.2 2.1 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 CAR27635.1 - 1.3e-11 44.3 0.0 2.7e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR27635.1 - 4e-07 30.5 0.0 9e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CAR27635.1 - 1.3e-05 24.4 0.1 2.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.10 CAR27635.1 - 2.5e-05 23.7 0.0 7.8e-05 22.1 0.0 1.8 1 0 0 1 1 1 1 Conserved hypothetical protein 95 TRAM PF01938.15 CAR27635.1 - 3.2e-05 23.6 0.1 5.5e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 TRAM domain Methyltransf_26 PF13659.1 CAR27635.1 - 3.6e-05 23.7 0.0 7.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CAR27635.1 - 4.7e-05 22.8 0.0 9.8e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.5 CAR27635.1 - 0.00025 20.6 0.0 0.0005 19.6 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Ubie_methyltran PF01209.13 CAR27635.1 - 0.00082 18.5 0.0 0.0015 17.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 CAR27635.1 - 0.0019 18.6 0.0 0.0046 17.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 CAR27635.1 - 0.0026 17.3 0.2 0.032 13.8 0.0 2.4 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_25 PF13649.1 CAR27635.1 - 0.0038 17.5 0.0 0.0088 16.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CAR27635.1 - 0.014 14.4 0.7 0.04 12.9 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase UPF0020 PF01170.13 CAR27635.1 - 0.031 13.8 0.1 0.089 12.3 0.0 1.7 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Ras PF00071.17 CAR27636.1 - 5.5e-48 162.4 0.0 7.1e-48 162.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR27636.1 - 3.2e-14 53.4 0.0 5.8e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAR27636.1 - 1.4e-05 24.3 0.0 2.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CAR27636.1 - 0.017 14.2 0.0 0.023 13.8 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF4601 PF15373.1 CAR27636.1 - 0.046 12.5 0.0 0.064 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4601) DHC_N1 PF08385.7 CAR27637.1 - 4.6e-89 299.3 24.3 4.6e-89 299.3 16.8 6.5 7 1 0 7 7 7 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 CAR27637.1 - 6.3e-87 291.7 13.2 6.3e-87 291.7 9.1 7.7 8 1 0 8 8 8 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CAR27637.1 - 3.5e-62 209.9 0.1 1.8e-60 204.3 0.0 3.1 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region D1 Dynein_heavy PF03028.10 CAR27637.1 - 6e-36 123.7 0.1 6e-36 123.7 0.1 2.2 3 0 0 3 3 2 1 Dynein heavy chain and region D6 of dynein motor AAA_8 PF12780.2 CAR27637.1 - 3.3e-29 101.7 2.3 9.2e-29 100.2 0.0 2.7 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 CAR27637.1 - 1.4e-26 92.7 0.1 5.9e-26 90.7 0.1 2.1 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 CAR27637.1 - 2.6e-24 85.6 9.2 5.3e-24 84.6 6.3 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 CAR27637.1 - 1.4e-22 79.8 0.7 6.7e-07 29.1 0.0 6.3 5 2 0 5 5 4 3 AAA domain (dynein-related subfamily) AAA PF00004.24 CAR27637.1 - 1.3e-15 57.7 1.4 0.0019 18.3 0.0 6.7 6 0 0 6 6 4 3 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.2 CAR27637.1 - 4.1e-15 55.5 0.5 4.3e-14 52.2 0.0 2.8 3 0 0 3 3 2 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 CAR27637.1 - 6.3e-14 52.2 3.8 0.0051 16.9 0.0 7.1 5 1 1 6 6 6 3 AAA domain AAA_16 PF13191.1 CAR27637.1 - 1.6e-10 41.2 1.0 0.51 10.3 0.0 6.0 4 1 0 5 5 5 3 AAA ATPase domain AAA_17 PF13207.1 CAR27637.1 - 6.4e-10 39.8 0.8 0.1 13.4 0.0 6.4 6 0 0 6 6 4 2 AAA domain AAA_18 PF13238.1 CAR27637.1 - 8e-09 35.8 3.7 1.1 9.5 0.0 7.1 5 1 0 5 5 5 2 AAA domain T2SE PF00437.15 CAR27637.1 - 2.4e-08 33.2 0.2 0.0085 15.0 0.4 4.1 4 0 0 4 4 4 2 Type II/IV secretion system protein Zeta_toxin PF06414.7 CAR27637.1 - 5.6e-07 28.8 0.0 0.018 14.1 0.0 4.3 4 0 0 4 4 4 2 Zeta toxin AAA_19 PF13245.1 CAR27637.1 - 1.8e-06 27.6 0.3 0.71 9.6 0.0 4.3 4 0 0 4 4 4 1 Part of AAA domain AAA_30 PF13604.1 CAR27637.1 - 3.3e-06 26.8 0.0 1.4 8.4 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.1 CAR27637.1 - 1.8e-05 24.6 0.0 0.33 10.8 0.0 4.5 4 0 0 4 4 4 1 AAA domain AAA_24 PF13479.1 CAR27637.1 - 0.00011 21.8 1.9 5.5 6.5 0.0 5.0 5 0 0 5 5 5 0 AAA domain AAA_28 PF13521.1 CAR27637.1 - 0.00061 19.7 0.0 12 5.8 0.0 4.2 4 0 0 4 4 4 0 AAA domain IstB_IS21 PF01695.12 CAR27637.1 - 0.00092 18.6 0.4 0.55 9.6 0.0 3.6 3 0 0 3 3 3 1 IstB-like ATP binding protein RNA_helicase PF00910.17 CAR27637.1 - 0.0011 19.1 0.2 11 6.2 0.0 4.5 4 0 0 4 4 3 0 RNA helicase ABC_tran PF00005.22 CAR27637.1 - 0.0033 17.7 1.4 1.8 8.8 0.0 4.2 3 0 0 3 3 3 1 ABC transporter cobW PF02492.14 CAR27637.1 - 0.01 15.2 2.6 0.11 11.8 0.0 2.9 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 CAR27637.1 - 0.012 15.0 0.2 8.9 5.7 0.0 3.4 3 0 0 3 3 3 0 FtsK/SpoIIIE family Mg_chelatase PF01078.16 CAR27637.1 - 0.019 14.1 2.7 0.55 9.3 0.0 3.7 5 0 0 5 5 4 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 CAR27637.1 - 0.052 12.9 0.0 16 4.8 0.0 3.9 4 0 0 4 4 4 0 AAA domain AAA_29 PF13555.1 CAR27637.1 - 0.067 12.7 0.0 41 3.8 0.0 3.6 3 0 0 3 3 3 0 P-loop containing region of AAA domain NTPase_1 PF03266.10 CAR27637.1 - 3.4 7.3 10.6 8.8 6.0 0.4 4.4 5 0 0 5 5 4 0 NTPase DBI_PRT PF02277.12 CAR27637.1 - 4.5 6.2 0.1 7.8 5.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyltransferase PAP2 PF01569.16 CAR27638.1 - 1.1e-15 57.5 1.8 1.1e-15 57.5 1.3 1.9 2 0 0 2 2 2 1 PAP2 superfamily Phyto_Pns9_10 PF05878.6 CAR27638.1 - 0.087 11.8 0.5 0.13 11.1 0.4 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 Fer4_5 PF12801.2 CAR27638.1 - 9.9 6.0 11.3 0.13 12.0 0.4 3.2 3 0 0 3 3 3 0 4Fe-4S binding domain Mito_carr PF00153.22 CAR27639.1 - 3.6e-63 209.3 2.8 1.8e-21 75.6 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Solute_trans_a PF03619.11 CAR27640.1 - 4.7e-80 268.8 12.5 6e-80 268.4 8.6 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Tmemb_18A PF09771.4 CAR27640.1 - 0.079 12.9 0.6 0.17 11.8 0.4 1.5 1 0 0 1 1 1 0 Transmembrane protein 188 Zn_dep_PLPC PF00882.13 CAR27641.1 - 1.4e-21 76.8 0.1 2.2e-21 76.2 0.1 1.3 1 0 0 1 1 1 1 Zinc dependent phospholipase C VCBS PF13517.1 CAR27641.1 - 0.013 15.8 0.1 0.048 14.0 0.0 2.0 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 CAR27641.1 - 0.025 14.2 0.1 0.17 11.6 0.0 2.3 2 0 0 2 2 2 0 FG-GAP repeat mIF3 PF14877.1 CAR27642.1 - 9.3e-68 227.1 7.6 9.3e-68 227.1 5.3 2.3 2 1 1 3 3 3 1 Mitochondrial translation initiation factor CPSase_L_D2 PF02786.12 CAR27643.1 - 4.3e-115 382.3 1.4 1.9e-83 278.9 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 CAR27643.1 - 5e-47 158.6 0.0 1.3e-46 157.3 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 CAR27643.1 - 8.4e-45 152.5 0.0 1.7e-44 151.5 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 CAR27643.1 - 4.1e-42 143.2 0.1 8e-42 142.2 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_chain PF00289.17 CAR27643.1 - 7.9e-41 138.6 0.1 5.2e-20 71.6 0.0 2.9 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 CAR27643.1 - 1.4e-39 134.6 0.0 3.8e-39 133.2 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 CAR27643.1 - 1.1e-33 116.4 0.3 2.1e-20 73.2 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain OTCace PF00185.19 CAR27643.1 - 1.6e-33 115.8 0.0 9.1e-33 113.3 0.0 2.4 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATPgrasp_Ter PF15632.1 CAR27643.1 - 1.8e-24 86.1 0.2 5.6e-13 48.3 0.0 3.5 3 0 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 CAR27643.1 - 1.1e-21 76.5 0.0 5.7e-21 74.2 0.0 2.4 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.8 CAR27643.1 - 1.8e-16 60.1 2.0 1.6e-08 34.2 0.3 3.0 3 0 0 3 3 3 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 CAR27643.1 - 6e-15 55.0 0.3 1.3e-06 27.9 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 CAR27643.1 - 1.1e-06 28.2 0.0 9.8e-05 21.8 0.0 2.5 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 CAR27643.1 - 2.8e-05 24.0 1.4 0.14 12.0 0.2 2.7 2 0 0 2 2 2 2 ATP-grasp domain DJ-1_PfpI PF01965.19 CAR27643.1 - 0.032 13.6 0.0 0.077 12.4 0.0 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family TrkH PF02386.11 CAR27644.1 - 1.1e-134 448.4 10.6 7.9e-134 445.6 2.6 2.1 2 0 0 2 2 2 2 Cation transport protein PI3K_1B_p101 PF10486.4 CAR27644.1 - 2 5.8 7.1 3.1 5.2 4.9 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Pkinase PF00069.20 CAR27645.1 - 2.9e-55 187.2 0.0 4.5e-55 186.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR27645.1 - 1.8e-38 132.0 0.0 2.6e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR27645.1 - 2e-05 23.6 0.0 3.5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 CAR27645.1 - 0.01 14.6 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 CAR27645.1 - 0.24 11.1 0.0 3 7.5 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-H2C2 PF09337.5 CAR27646.1 - 2.3e-17 62.1 1.5 3.9e-17 61.3 1.0 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_4 PF13420.1 CAR27646.1 - 0.0023 17.8 0.0 0.0072 16.2 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CAR27646.1 - 0.0023 17.9 0.0 0.0049 16.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Nop14 PF04147.7 CAR27646.1 - 0.44 8.4 25.5 0.61 7.9 17.7 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 CAR27646.1 - 2.4 7.3 22.7 4.7 6.3 15.8 1.5 1 0 0 1 1 1 0 SDA1 Astro_capsid PF03115.9 CAR27646.1 - 7 4.7 8.6 10 4.1 6.0 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor TFIIA PF03153.8 CAR27646.1 - 9.6 5.9 19.3 21 4.8 13.4 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CN_hydrolase PF00795.17 CAR27647.1 - 1.9e-26 92.5 0.0 3.1e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase GCD14 PF08704.5 CAR27648.1 - 2.5e-78 262.9 0.0 2.3e-77 259.8 0.0 2.0 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 CAR27648.1 - 5.4e-05 23.2 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 CAR27648.1 - 0.00013 21.0 0.0 0.00025 20.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.2 CAR27648.1 - 0.0013 19.2 0.0 0.0043 17.6 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAR27648.1 - 0.0027 17.3 0.0 0.0049 16.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CAR27648.1 - 0.02 14.4 0.0 0.042 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF3748 PF12566.3 CAR27648.1 - 0.026 14.4 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3748) MTS PF05175.9 CAR27648.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain LSM PF01423.17 CAR27649.1 - 5.3e-14 51.5 0.1 9.4e-14 50.7 0.1 1.4 1 0 0 1 1 1 1 LSM domain DUF1687 PF07955.6 CAR27650.1 - 9.5e-34 116.2 0.4 1e-33 116.1 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) DUF2413 PF10310.4 CAR27651.1 - 2.2e-107 359.6 40.8 4.1e-107 358.7 28.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2413) BTV_NS2 PF04514.7 CAR27651.1 - 0.0033 16.3 1.5 0.0033 16.3 1.0 3.2 3 0 0 3 3 3 2 Bluetongue virus non-structural protein NS2 Alb1 PF09135.6 CAR27652.1 - 6.9e-17 62.0 9.3 1.1e-16 61.4 6.4 1.3 1 0 0 1 1 1 1 Alb1 DUF3073 PF11273.3 CAR27652.1 - 5 7.7 7.3 2.5 8.7 3.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3073) Ribul_P_3_epim PF00834.14 CAR27653.1 - 2.6e-70 235.6 0.0 3.8e-70 235.0 0.0 1.2 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.19 CAR27653.1 - 0.023 14.1 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family ThiG PF05690.9 CAR27653.1 - 0.026 13.6 0.1 0.036 13.1 0.1 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG NAP PF00956.13 CAR27654.1 - 2e-76 256.3 8.0 2e-76 256.3 5.5 2.4 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Mst1_SARAH PF11629.3 CAR27654.1 - 0.41 10.5 4.5 0.74 9.6 0.1 2.5 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 Innate_immun PF12782.2 CAR27656.1 - 3.1 6.9 18.5 2 7.5 9.1 2.2 2 0 0 2 2 2 0 Invertebrate innate immunity transcript family Pho86 PF11124.3 CAR27657.1 - 1.6e-79 267.0 1.3 1.8e-79 266.8 0.9 1.0 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 OppC_N PF12911.2 CAR27657.1 - 9 5.7 6.6 0.55 9.6 0.2 2.2 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Lectin_leg-like PF03388.8 CAR27658.1 - 7.7e-13 48.0 0.0 3.1e-08 33.0 0.0 2.3 2 0 0 2 2 2 2 Legume-like lectin family His_Phos_1 PF00300.17 CAR27659.1 - 7.7e-28 97.5 0.1 9.8e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 CAR27659.1 - 0.0057 16.0 0.0 0.0084 15.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) SUN PF03856.8 CAR27660.1 - 4.4e-95 317.7 19.4 7.1e-95 317.0 13.5 1.3 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Macoilin PF09726.4 CAR27660.1 - 2.3 6.3 14.2 3.2 5.9 9.9 1.1 1 0 0 1 1 1 0 Transmembrane protein MSP1_C PF07462.6 CAR27660.1 - 6.8 4.9 6.6 9.7 4.4 4.6 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus ASF1_hist_chap PF04729.8 CAR27661.1 - 9e-66 220.2 0.1 9e-66 220.2 0.1 1.5 2 0 0 2 2 2 1 ASF1 like histone chaperone Nop14 PF04147.7 CAR27661.1 - 0.0015 16.5 39.8 0.0019 16.2 27.6 1.1 1 0 0 1 1 1 1 Nop14-like family CENP-T PF15511.1 CAR27661.1 - 0.014 14.6 27.9 0.018 14.3 19.3 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CobT PF06213.7 CAR27661.1 - 0.028 13.5 33.5 0.043 12.9 23.2 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.9 CAR27661.1 - 0.19 9.7 29.5 0.25 9.3 20.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 CAR27661.1 - 0.97 8.7 35.2 1.4 8.2 24.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Daxx PF03344.10 CAR27661.1 - 1.7 7.0 43.5 2 6.8 30.2 1.1 1 0 0 1 1 1 0 Daxx Family Spore_coat_CotO PF14153.1 CAR27661.1 - 1.8 7.9 25.7 2.9 7.2 17.8 1.4 1 0 0 1 1 1 0 Spore coat protein CotO YL1 PF05764.8 CAR27661.1 - 2.2 7.8 36.3 3.1 7.3 25.1 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Lin-8 PF03353.10 CAR27661.1 - 4.9 6.3 20.9 5.9 6.0 14.5 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Hid1 PF12722.2 CAR27661.1 - 8.6 3.8 13.3 10 3.6 9.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DnaJ PF00226.26 CAR27662.1 - 0.0054 16.4 0.0 0.014 15.0 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain AA_permease PF00324.16 CAR27663.1 - 1.2e-150 502.0 37.6 1.4e-150 501.8 26.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CAR27663.1 - 2.7e-40 138.2 39.0 3.4e-40 137.8 27.0 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2207 PF09972.4 CAR27663.1 - 2.6 6.5 5.8 5.6 5.4 0.8 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Peptidase_M22 PF00814.20 CAR27664.1 - 4.3e-82 275.6 0.0 5.4e-82 275.2 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family DASH_Spc34 PF08657.5 CAR27665.1 - 4.1e-60 203.6 0.9 4.8e-60 203.4 0.6 1.0 1 0 0 1 1 1 1 DASH complex subunit Spc34 Vps39_2 PF10367.4 CAR27665.1 - 0.067 13.3 1.0 0.19 11.9 0.7 1.8 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Occludin_ELL PF07303.8 CAR27665.1 - 0.24 12.1 5.0 0.41 11.4 2.0 2.2 2 0 0 2 2 2 0 Occludin homology domain OmpH PF03938.9 CAR27665.1 - 0.38 10.6 8.0 0.7 9.8 5.5 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1192 PF06698.6 CAR27665.1 - 0.72 9.7 6.8 1.5 8.6 1.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) WD40 PF00400.27 CAR27666.1 - 4.2e-33 112.0 8.8 2.7e-08 33.3 0.1 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 CAR27666.1 - 4.1e-09 35.1 6.7 3.8e-05 22.0 0.1 4.3 1 1 3 4 4 4 3 Nucleoporin Nup120/160 DUF3249 PF11615.3 CAR27666.1 - 0.00011 21.8 0.2 0.016 14.9 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3249) PQQ_2 PF13360.1 CAR27666.1 - 0.0017 17.8 0.5 1.1 8.6 0.1 2.4 1 1 1 2 2 2 2 PQQ-like domain Mdv1 PF11542.3 CAR27666.1 - 0.0025 17.7 0.9 0.0059 16.4 0.6 1.6 1 0 0 1 1 1 1 Mitochondrial division protein 1 BBS2_Mid PF14783.1 CAR27666.1 - 0.0035 17.1 0.7 0.035 13.8 0.0 2.9 3 1 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Cpn60_TCP1 PF00118.19 CAR27667.1 - 7.2e-145 483.3 5.4 8.4e-145 483.0 3.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Snf7 PF03357.16 CAR27668.1 - 9e-16 57.7 16.9 1.4e-15 57.1 11.7 1.3 1 0 0 1 1 1 1 Snf7 DUF2580 PF10824.3 CAR27668.1 - 0.11 12.8 0.1 0.11 12.8 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2580) Baculo_PEP_C PF04513.7 CAR27668.1 - 0.14 11.9 2.9 0.12 12.1 0.3 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GrpE PF01025.14 CAR27668.1 - 1.9 8.0 13.5 0.05 13.1 4.4 1.8 1 1 1 2 2 2 0 GrpE XH PF03469.9 CAR27668.1 - 2.6 7.7 8.1 5.6 6.6 1.6 2.8 1 1 2 3 3 3 0 XH domain GATA PF00320.22 CAR27669.1 - 3.4e-14 51.8 1.5 3.4e-14 51.8 1.1 1.8 2 0 0 2 2 2 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 CAR27669.1 - 0.11 11.8 0.7 0.24 10.7 0.5 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding IncA PF04156.9 CAR27669.1 - 1.2 8.7 18.5 1.9 8.0 12.8 1.3 1 0 0 1 1 1 0 IncA protein GCR1_C PF12550.3 CAR27670.1 - 5.4e-22 77.4 1.0 5.4e-22 77.4 0.7 2.0 2 1 0 2 2 2 1 Transcriptional activator of glycolytic enzymes AAA PF00004.24 CAR27671.1 - 3.1e-42 143.9 0.0 7.3e-42 142.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CAR27671.1 - 4.1e-07 30.0 0.6 7.7e-07 29.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 CAR27671.1 - 1.6e-05 24.0 0.0 2.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CAR27671.1 - 3.3e-05 24.0 0.2 0.0017 18.5 0.1 2.7 1 1 0 1 1 1 1 AAA domain Vps4_C PF09336.5 CAR27671.1 - 4.3e-05 23.3 0.0 0.00046 20.0 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain TIP49 PF06068.8 CAR27671.1 - 0.00012 20.9 0.0 0.00012 20.9 0.0 1.5 2 0 0 2 2 2 1 TIP49 C-terminus AAA_14 PF13173.1 CAR27671.1 - 0.00036 20.4 0.1 0.0026 17.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CAR27671.1 - 0.00043 20.0 0.1 0.009 15.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CAR27671.1 - 0.0012 18.2 0.3 0.26 10.6 0.1 2.5 1 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CAR27671.1 - 0.0028 16.8 0.1 0.0064 15.6 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 CAR27671.1 - 0.0032 17.7 2.8 0.026 14.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CAR27671.1 - 0.0042 16.5 0.0 0.0084 15.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 CAR27671.1 - 0.0052 16.4 0.2 0.024 14.3 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_11 PF13086.1 CAR27671.1 - 0.0054 16.3 4.3 0.016 14.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 CAR27671.1 - 0.011 15.5 3.2 0.98 9.2 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_17 PF13207.1 CAR27671.1 - 0.017 15.8 2.9 0.03 15.1 0.0 2.6 2 1 0 2 2 1 0 AAA domain AAA_16 PF13191.1 CAR27671.1 - 0.028 14.4 1.9 0.061 13.3 0.0 2.5 2 2 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.1 CAR27671.1 - 0.031 14.1 1.2 0.045 13.6 0.0 2.0 2 1 0 2 2 1 0 AAA domain AAA_24 PF13479.1 CAR27671.1 - 0.045 13.3 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 CAR27671.1 - 0.05 12.7 0.8 3.5 6.6 0.1 2.5 1 1 1 2 2 2 0 KaiC NACHT PF05729.7 CAR27671.1 - 0.053 13.1 0.2 1.6 8.3 0.0 2.4 1 1 1 2 2 2 0 NACHT domain Sigma54_activat PF00158.21 CAR27671.1 - 0.054 12.9 0.1 0.53 9.7 0.0 2.4 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 CAR27671.1 - 0.079 12.1 0.0 0.35 10.0 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.17 CAR27671.1 - 0.12 12.5 0.1 0.39 10.9 0.0 1.9 2 0 0 2 2 1 0 RNA helicase Glyco_transf_15 PF01793.11 CAR27672.1 - 4.5e-114 380.8 9.0 5.5e-114 380.5 6.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase UCH PF00443.24 CAR27673.1 - 1.4e-36 126.0 3.3 5.2e-33 114.3 0.4 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Pox_F15 PF04596.7 CAR27673.1 - 0.028 14.0 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 Poxvirus protein F15 Zip PF02535.17 CAR27673.1 - 0.65 8.9 4.4 0.14 11.1 0.1 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter SH3_1 PF00018.23 CAR27674.1 - 6.3e-22 76.7 0.1 4.9e-10 38.6 0.0 3.3 4 0 0 4 4 4 2 SH3 domain PX PF00787.19 CAR27674.1 - 1.6e-12 47.2 0.0 3.4e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 PX domain SH3_9 PF14604.1 CAR27674.1 - 3e-08 33.1 0.8 2.7e-05 23.6 0.0 3.4 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.12 CAR27674.1 - 5e-08 32.3 0.2 7.1e-07 28.6 0.0 2.7 3 0 0 3 3 3 1 Variant SH3 domain PB1 PF00564.19 CAR27674.1 - 1e-07 31.4 0.2 2e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 PB1 domain Med3 PF11593.3 CAR27674.1 - 0.17 11.1 5.2 0.28 10.3 3.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF3947 PF13135.1 CAR27674.1 - 0.2 11.8 12.5 0.43 10.8 8.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) VPS9 PF02204.13 CAR27676.1 - 5.9e-19 68.0 1.3 1.2e-18 67.0 0.9 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain polyprenyl_synt PF00348.12 CAR27677.1 - 1.8e-44 151.5 0.0 2.1e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DER1 PF04511.10 CAR27678.1 - 5.3e-35 120.7 8.0 6e-35 120.5 5.5 1.0 1 0 0 1 1 1 1 Der1-like family DUF3605 PF12239.3 CAR27679.1 - 6.3e-35 120.3 0.2 7.7e-35 120.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Myosin_head PF00063.16 CAR27680.1 - 9.4e-269 893.1 8.2 9.4e-269 893.1 5.7 1.7 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 CAR27680.1 - 1.2e-32 111.9 3.2 1.2e-32 111.9 2.2 2.6 2 0 0 2 2 2 1 DIL domain AAA_22 PF13401.1 CAR27680.1 - 0.00049 20.2 2.0 0.0015 18.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain Myosin_N PF02736.14 CAR27680.1 - 0.0088 15.7 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain ABC_tran PF00005.22 CAR27680.1 - 0.12 12.6 0.0 0.12 12.6 0.0 3.2 2 1 0 2 2 2 0 ABC transporter AAA_19 PF13245.1 CAR27680.1 - 0.14 11.9 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain IQ PF00612.22 CAR27680.1 - 0.4 10.4 18.7 1.8 8.4 0.5 5.3 6 0 0 6 6 6 0 IQ calmodulin-binding motif Synaptobrevin PF00957.16 CAR27681.1 - 1.1e-31 108.3 0.2 1.2e-31 108.1 0.1 1.0 1 0 0 1 1 1 1 Synaptobrevin TMEM117 PF15113.1 CAR27681.1 - 0.02 13.4 0.2 0.025 13.1 0.1 1.0 1 0 0 1 1 1 0 TMEM117 protein family DUF1705 PF08019.7 CAR27681.1 - 0.047 13.2 0.6 0.059 12.8 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1705) Phospholamban PF04272.9 CAR27681.1 - 0.06 12.7 2.0 0.095 12.1 1.4 1.3 1 0 0 1 1 1 0 Phospholamban PRT_C PF08372.5 CAR27681.1 - 0.12 11.8 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal Phage_int_SAM_4 PF13495.1 CAR27682.1 - 0.43 10.9 4.0 27 5.1 1.8 2.9 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain DUF2040 PF09745.4 CAR27683.1 - 6.2e-08 32.5 11.8 6.2e-08 32.5 8.2 2.4 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) DNA_pol_A PF00476.15 CAR27684.1 - 3.3e-106 355.1 0.0 5.2e-106 354.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A vATP-synt_E PF01991.13 CAR27685.1 - 2.5e-58 196.6 14.9 2.9e-58 196.4 10.3 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Phlebovirus_NSM PF07246.6 CAR27685.1 - 0.032 13.3 12.7 0.012 14.8 6.8 1.6 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M DUF763 PF05559.6 CAR27685.1 - 0.75 8.6 4.4 1.1 8.1 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF763) CorA PF01544.13 CAR27686.1 - 1.2e-09 37.6 2.1 2e-09 36.8 1.4 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein SKIP_SNW PF02731.10 CAR27688.1 - 1.3e-47 161.2 10.0 1.3e-47 161.2 6.9 2.7 2 0 0 2 2 2 1 SKIP/SNW domain RNase_P_Rpp14 PF01900.14 CAR27689.1 - 9.8e-33 112.2 0.1 1.2e-32 111.9 0.1 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family tRNA-synt_2c PF01411.14 CAR27690.1 - 3.2e-222 738.7 0.1 7.4e-222 737.5 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 CAR27690.1 - 1.2e-18 66.6 0.2 3.1e-18 65.3 0.1 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 CAR27690.1 - 2.5e-07 30.3 1.9 6.5e-07 28.9 1.3 1.7 1 0 0 1 1 1 1 DHHA1 domain RNase_PH_C PF03725.10 CAR27690.1 - 0.093 12.6 0.1 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 UDP-g_GGTase PF06427.6 CAR27691.1 - 6.8e-11 41.8 0.0 1.6e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Fungal_trans PF04082.13 CAR27692.1 - 9.2e-34 116.4 4.3 2.1e-33 115.3 0.8 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR27692.1 - 1.7e-08 34.2 10.7 3.3e-08 33.2 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SWIRM PF04433.12 CAR27693.1 - 2.7e-14 53.0 0.0 6.9e-14 51.7 0.0 1.7 2 0 0 2 2 2 1 SWIRM domain NT-C2 PF10358.4 CAR27693.1 - 0.12 11.8 0.0 0.3 10.5 0.0 1.6 2 0 0 2 2 2 0 N-terminal C2 in EEIG1 and EHBP1 proteins PBP1_TM PF14812.1 CAR27693.1 - 3.1 8.1 11.6 5.1 7.4 4.0 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UQ_con PF00179.21 CAR27694.1 - 4.2e-49 165.5 0.1 4.8e-49 165.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CAR27694.1 - 0.0006 19.5 0.0 0.0007 19.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 CAR27694.1 - 0.0014 18.2 1.0 0.0025 17.4 0.7 1.4 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 CAR27694.1 - 0.012 15.5 0.2 0.02 14.7 0.1 1.6 1 1 0 1 1 1 0 RWD domain Mis12 PF05859.7 CAR27695.1 - 2.6e-40 137.5 3.6 3.3e-40 137.2 1.9 1.6 1 1 0 1 1 1 1 Mis12 protein DALR_1 PF05746.10 CAR27695.1 - 0.46 10.4 3.9 0.72 9.8 0.6 2.4 1 1 1 2 2 2 0 DALR anticodon binding domain SHS2_Rpb7-N PF03876.12 CAR27696.1 - 9.8e-11 41.6 0.0 1.9e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rpb1_5 PF04998.12 CAR27697.1 - 5.7e-99 330.8 1.4 1.4e-98 329.5 0.0 2.3 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 CAR27697.1 - 2.2e-63 213.1 0.4 9.3e-63 211.0 0.1 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 CAR27697.1 - 4.9e-40 136.8 0.4 1.8e-38 131.7 0.0 3.2 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 CAR27697.1 - 1.6e-22 79.3 0.1 1.6e-22 79.3 0.1 3.0 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.7 CAR27697.1 - 1.5e-18 67.2 5.9 1.5e-18 67.2 4.1 4.7 4 1 0 4 4 4 1 RNA polymerase Rpb1, domain 1 Daxx PF03344.10 CAR27697.1 - 7.9 4.8 26.5 2.3 6.5 13.5 2.2 2 0 0 2 2 2 0 Daxx Family GTP_EFTU PF00009.22 CAR27698.1 - 7.6e-31 107.0 0.0 7.6e-31 107.0 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 CAR27698.1 - 3.3e-20 72.0 0.0 9.2e-20 70.5 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 CAR27698.1 - 5.3e-14 52.0 1.5 5.7e-10 39.1 0.0 3.0 2 0 0 2 2 2 2 Elongation factor Tu domain 2 ATP_bind_1 PF03029.12 CAR27698.1 - 0.0028 17.2 0.1 0.024 14.1 0.0 2.4 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 CAR27698.1 - 0.0036 17.4 0.0 0.016 15.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain TGS PF02824.16 CAR27699.1 - 2.6e-21 75.2 0.1 4.7e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 CAR27699.1 - 1e-16 60.9 0.1 2.5e-16 59.6 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CAR27699.1 - 1.2e-08 34.3 0.1 2.9e-08 33.1 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CAR27699.1 - 0.00093 19.0 0.6 0.56 10.0 0.0 2.4 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 CAR27699.1 - 0.0062 15.3 0.1 0.014 14.1 0.1 1.6 1 0 0 1 1 1 1 ArgK protein Miro PF08477.8 CAR27699.1 - 0.016 15.7 0.0 0.033 14.6 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein HLH PF00010.21 CAR27701.1 - 2.5e-22 78.3 0.2 7.2e-22 76.8 0.1 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Med3 PF11593.3 CAR27701.1 - 0.14 11.3 4.8 0.17 11.0 3.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Hamartin PF04388.7 CAR27701.1 - 0.29 9.7 2.7 0.32 9.6 1.9 1.1 1 0 0 1 1 1 0 Hamartin protein IMS PF00817.15 CAR27702.1 - 2.3e-29 102.1 0.0 6.1e-29 100.7 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 CAR27702.1 - 2.9e-12 46.6 0.0 1.1e-11 44.6 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain BRCT PF00533.21 CAR27702.1 - 9.8e-08 32.0 0.0 2.1e-06 27.7 0.0 2.8 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DUF4414 PF14377.1 CAR27702.1 - 0.00063 19.6 1.2 0.0024 17.7 0.8 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4414) PTCB-BRCT PF12738.2 CAR27702.1 - 0.00093 19.0 0.0 0.002 17.9 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain IMS_HHH PF11798.3 CAR27702.1 - 0.0098 15.8 0.0 0.032 14.2 0.0 2.0 1 0 0 1 1 1 1 IMS family HHH motif HHH PF00633.18 CAR27702.1 - 0.1 12.3 0.0 0.73 9.6 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif PK PF00224.16 CAR27703.1 - 1.8e-164 546.4 2.7 2.3e-164 546.0 1.8 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 CAR27703.1 - 4.6e-30 103.5 0.2 2.4e-29 101.2 0.0 2.3 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 CAR27703.1 - 6.4e-06 25.2 0.2 1.7e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family HEAT_2 PF13646.1 CAR27704.1 - 0.065 13.5 0.1 0.65 10.3 0.0 2.7 2 0 0 2 2 2 0 HEAT repeats MNE1 PF13762.1 CAR27705.1 - 1e-43 148.9 7.1 1e-43 148.9 4.9 3.3 3 1 0 3 3 3 1 Mitochondrial splicing apparatus component Pkinase PF00069.20 CAR27706.1 - 6.1e-67 225.4 0.0 1.4e-66 224.3 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR27706.1 - 6.8e-30 103.9 0.0 1.2e-29 103.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 CAR27706.1 - 1.7e-16 60.0 0.0 4.3e-15 55.5 0.0 2.6 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.1 CAR27706.1 - 1.3e-06 27.6 0.0 1.8e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CAR27706.1 - 0.0036 16.3 0.0 0.0068 15.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SOG2 PF10428.4 CAR27708.1 - 4e-113 378.4 15.6 4e-113 378.4 10.8 2.0 2 0 0 2 2 2 1 RAM signalling pathway protein LRR_4 PF12799.2 CAR27708.1 - 1.6e-18 65.8 12.0 1.1e-09 37.6 1.2 3.9 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAR27708.1 - 3.6e-15 55.4 12.2 1e-08 34.7 0.7 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 CAR27708.1 - 4.9e-09 34.9 9.3 0.054 13.5 0.1 5.9 4 1 0 4 4 4 3 Leucine Rich Repeat LRR_7 PF13504.1 CAR27708.1 - 0.00012 21.6 5.9 0.55 10.6 0.1 5.0 4 0 0 4 4 4 1 Leucine rich repeat LRR_6 PF13516.1 CAR27708.1 - 0.00063 19.5 7.6 0.12 12.5 0.1 4.8 4 0 0 4 4 4 1 Leucine Rich repeat LRR_9 PF14580.1 CAR27708.1 - 0.1 12.1 1.6 0.14 11.7 0.3 1.8 2 0 0 2 2 2 0 Leucine-rich repeat DUF4175 PF13779.1 CAR27708.1 - 1.4 6.5 10.8 2 6.0 7.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SpecificRecomb PF10136.4 CAR27708.1 - 5.2 4.9 9.1 0.033 12.2 0.3 1.6 2 0 0 2 2 2 0 Site-specific recombinase Cyto_heme_lyase PF01265.12 CAR27709.1 - 7.8e-72 241.9 0.0 9.4e-72 241.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase PPR PF01535.15 CAR27710.1 - 0.072 13.0 0.3 61 3.9 0.0 4.0 2 1 1 3 3 3 0 PPR repeat FeoC PF09012.5 CAR27710.1 - 0.1 12.3 0.0 0.56 9.9 0.0 2.3 2 0 0 2 2 2 0 FeoC like transcriptional regulator Cyclin_N PF00134.18 CAR27711.1 - 1.7e-23 82.6 1.1 3.4e-23 81.5 0.8 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain COMPASS-Shg1 PF05205.7 CAR27711.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 Cupin_8 PF13621.1 CAR27712.1 - 2e-53 181.4 0.0 2.2e-51 174.7 0.0 2.2 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 CAR27712.1 - 4.5e-05 22.8 0.2 0.0076 15.5 0.0 2.7 3 0 0 3 3 3 2 Cupin superfamily protein JmjC PF02373.17 CAR27712.1 - 0.015 15.5 0.0 0.039 14.1 0.0 1.7 1 0 0 1 1 1 0 JmjC domain, hydroxylase tRNA_synt_1c_R1 PF04558.10 CAR27713.1 - 0.031 13.8 0.1 0.063 12.8 0.1 1.4 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_2c PF01411.14 CAR27713.1 - 0.051 11.8 0.3 1.1 7.4 0.1 2.0 2 0 0 2 2 2 0 tRNA synthetases class II (A) ETF_QO PF05187.8 CAR27714.1 - 6.4e-40 135.5 0.0 1e-39 134.9 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 CAR27714.1 - 9.9e-13 47.7 0.8 8.7e-06 24.8 0.1 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CAR27714.1 - 3.9e-09 35.8 0.1 0.0021 17.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 CAR27714.1 - 8e-09 34.9 0.0 0.00053 19.1 0.1 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.1 CAR27714.1 - 1.6e-06 27.9 0.0 4.7e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CAR27714.1 - 1.7e-06 28.2 0.0 7.5e-06 26.1 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CAR27714.1 - 4.9e-05 21.9 0.1 0.0011 17.5 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 CAR27714.1 - 0.00019 21.7 0.1 0.66 10.4 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CAR27714.1 - 0.00035 20.5 0.0 0.00087 19.2 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CAR27714.1 - 0.00063 18.9 0.0 0.0014 17.7 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CAR27714.1 - 0.00069 19.4 0.1 0.0016 18.2 0.1 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 CAR27714.1 - 0.00094 18.3 0.5 0.0044 16.1 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.9 CAR27714.1 - 0.0041 15.8 0.1 0.07 11.7 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase Fer4_7 PF12838.2 CAR27714.1 - 0.006 16.9 0.6 0.019 15.3 0.4 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Lycopene_cycl PF05834.7 CAR27714.1 - 0.034 13.0 0.1 0.049 12.5 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DUF164 PF02591.10 CAR27714.1 - 0.21 11.4 1.2 50 3.8 0.1 3.7 4 0 0 4 4 4 0 Putative zinc ribbon domain CDC24 PF06395.6 CAR27715.1 - 1.1e-36 124.7 0.6 2.7e-36 123.5 0.4 1.7 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.15 CAR27715.1 - 1.8e-36 125.6 4.2 5.2e-36 124.2 2.9 1.8 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.1 CAR27715.1 - 2.6e-23 82.3 0.3 2.9e-22 79.0 0.2 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PB1 PF00564.19 CAR27715.1 - 6.5e-07 28.9 2.6 1.4e-06 27.8 0.3 2.7 3 0 0 3 3 3 1 PB1 domain COPIIcoated_ERV PF07970.7 CAR27716.1 - 3.2e-75 252.5 0.1 3.9e-75 252.2 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CAR27716.1 - 2.9e-32 110.5 0.5 7.5e-32 109.1 0.1 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) PX PF00787.19 CAR27717.1 - 2.2e-21 75.7 0.0 3.3e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 PX domain CBFD_NFYB_HMF PF00808.18 CAR27718.1 - 3.5e-21 75.0 1.3 3.5e-21 75.0 0.9 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CAR27718.1 - 2e-15 56.6 0.1 2.9e-15 56.1 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 CAR27718.1 - 0.018 14.8 0.2 0.031 14.0 0.1 1.4 1 0 0 1 1 1 0 CENP-S associating Centromere protein X DUF3453 PF11935.3 CAR27719.1 - 3.6e-62 209.9 0.3 3.6e-62 209.9 0.2 2.3 4 0 0 4 4 4 1 Domain of unknown function (DUF3453) Ipi1_N PF12333.3 CAR27719.1 - 0.031 14.2 0.4 0.95 9.4 0.0 3.3 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation SAM_2 PF07647.12 CAR27720.1 - 4.3e-11 42.4 0.4 1.7e-10 40.6 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CAR27720.1 - 5.6e-08 32.8 0.1 1.1e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDEase_I PF00233.14 CAR27721.1 - 9.5e-50 169.5 0.6 1.5e-48 165.6 0.2 2.3 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 CAR27721.1 - 0.0011 18.9 0.1 0.003 17.5 0.0 1.8 1 1 0 1 1 1 1 HD domain Glycos_transf_N PF04413.11 CAR27721.1 - 0.053 12.6 0.1 0.087 11.9 0.0 1.3 1 0 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) Ku_C PF03730.9 CAR27721.1 - 0.083 13.4 0.1 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 Ku70/Ku80 C-terminal arm Hph PF13694.1 CAR27722.1 - 5.3e-61 206.0 1.7 5.3e-61 206.0 1.2 2.7 3 0 0 3 3 3 1 Sec63/Sec62 complex-interacting family Orexin_rec2 PF03827.8 CAR27722.1 - 0.062 13.3 0.1 1.3 9.1 0.0 2.6 1 1 1 2 2 2 0 Orexin receptor type 2 Sec8_exocyst PF04048.9 CAR27722.1 - 0.33 10.5 10.3 0.29 10.7 1.3 2.3 1 1 0 2 2 2 0 Sec8 exocyst complex component specific domain Saw1 PF11561.3 CAR27723.1 - 2.2e-59 200.4 7.0 2.6e-59 200.2 4.9 1.0 1 0 0 1 1 1 1 Single strand annealing-weakened 1 DUF2404 PF10296.4 CAR27723.1 - 0.063 13.4 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) Aldedh PF00171.17 CAR27724.1 - 2.9e-14 52.2 0.1 3.1e-11 42.3 0.0 2.2 2 0 0 2 2 2 2 Aldehyde dehydrogenase family HAD PF12710.2 CAR27725.1 - 6.3e-20 72.1 0.1 1.8e-19 70.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CAR27725.1 - 1.3e-17 63.6 0.6 2.4e-17 62.7 0.4 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CAR27725.1 - 2.6e-13 50.9 0.6 5.5e-10 40.0 0.1 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CAR27725.1 - 3.6e-09 36.4 0.0 1e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CAR27725.1 - 0.0016 18.0 0.1 0.011 15.2 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Mt_ATP-synt_B PF05405.9 CAR27725.1 - 0.046 13.1 0.1 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) HAD_2 PF13419.1 CAR27725.1 - 0.063 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF4083 PF13314.1 CAR27725.1 - 0.6 9.9 3.0 25 4.7 0.3 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Ribosomal_L28e PF01778.12 CAR27726.1 - 1e-32 112.9 3.1 1e-32 112.9 2.1 1.7 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 CAR27726.1 - 1.2e-32 111.9 16.3 1.2e-32 111.9 11.3 2.9 3 1 0 3 3 3 1 Mak16 protein C-terminal region PYC_OADA PF02436.13 CAR27726.1 - 0.16 11.4 1.6 0.29 10.5 1.1 1.6 1 1 0 1 1 1 0 Conserved carboxylase domain Latrophilin PF02354.11 CAR27726.1 - 1.5 7.4 7.5 0.4 9.3 3.2 1.4 2 0 0 2 2 2 0 Latrophilin Cytoplasmic C-terminal region RasGEF PF00617.14 CAR27727.1 - 1.6e-37 129.0 3.0 1.6e-37 129.0 0.8 2.0 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 CAR27727.1 - 2.6e-12 46.7 1.2 2.6e-12 46.7 0.8 3.3 4 0 0 4 4 4 1 RasGEF N-terminal motif LDB19 PF13002.2 CAR27728.1 - 2.5e-100 333.7 0.3 4.9e-100 332.7 0.2 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 CAR27728.1 - 0.0023 17.7 0.0 0.0058 16.4 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain PMT PF02366.13 CAR27729.1 - 1.1e-89 300.0 23.5 1.1e-89 300.0 16.3 2.5 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CAR27729.1 - 1.2e-24 86.9 0.1 2.8e-24 85.6 0.1 1.6 1 1 0 1 1 1 1 MIR domain Nucleoside_tran PF01733.13 CAR27730.1 - 1.3e-58 198.5 28.3 2.3e-42 145.2 5.1 2.5 2 1 1 3 3 3 2 Nucleoside transporter Exo_endo_phos PF03372.18 CAR27731.1 - 2.1e-23 83.5 0.1 3.3e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 CAR27731.1 - 3.9e-17 61.4 13.0 3.1e-10 39.4 2.3 4.3 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAR27731.1 - 2.4e-14 52.8 8.9 3.6e-10 39.4 1.1 2.7 1 1 2 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 CAR27731.1 - 2e-08 33.1 13.9 0.0017 18.1 0.3 5.7 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 CAR27731.1 - 1.3e-06 27.6 8.6 0.0047 16.9 0.4 5.3 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 CAR27731.1 - 0.0013 18.5 4.8 0.11 12.6 0.1 4.6 4 0 0 4 4 4 1 Leucine Rich repeat Exo_endo_phos_2 PF14529.1 CAR27731.1 - 0.01 15.4 0.0 0.065 12.8 0.0 2.5 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase RCC1 PF00415.13 CAR27732.1 - 3.2e-07 30.4 3.2 0.0045 17.1 0.5 3.7 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CAR27732.1 - 5.9e-06 25.7 11.2 0.00031 20.2 0.4 3.9 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat SNF2_N PF00176.18 CAR27733.1 - 2.8e-70 236.5 3.2 5.6e-70 235.4 0.6 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CAR27733.1 - 9.7e-15 54.2 0.0 4.7e-14 52.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Med15_fungi PF05397.7 CAR27734.1 - 2.2e-37 127.5 4.4 2.2e-37 127.5 3.1 6.2 5 2 0 6 6 6 1 Mediator complex subunit 15 GSH_synth_ATP PF03917.12 CAR27735.1 - 1.9e-122 408.4 0.0 2.3e-122 408.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 CAR27735.1 - 7e-34 116.0 0.0 1.3e-33 115.2 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase EI24 PF07264.6 CAR27736.1 - 0.13 11.7 6.3 0.23 10.8 4.3 1.6 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) 2OG-FeII_Oxy_2 PF13532.1 CAR27737.1 - 1.6e-23 83.5 0.1 2.3e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 CAR27737.1 - 0.01 16.1 0.2 0.02 15.1 0.1 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Zn_ribbon_recom PF13408.1 CAR27737.1 - 0.012 15.8 3.8 0.012 15.8 2.6 2.0 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain DUF3674 PF12426.3 CAR27738.1 - 4.1e-05 22.8 0.4 7.8e-05 21.9 0.2 1.4 1 0 0 1 1 1 1 RNA dependent RNA polymerase Pkinase PF00069.20 CAR27740.1 - 2.6e-62 210.3 0.0 5.7e-62 209.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR27740.1 - 2.7e-22 79.0 0.0 4.7e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR27740.1 - 1.7e-09 37.0 0.0 3e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CAR27740.1 - 0.0012 18.6 0.0 0.0071 16.1 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CAR27740.1 - 0.0028 16.7 0.0 0.0057 15.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_9 PF13426.1 CAR27740.1 - 0.041 14.2 0.0 7.7 6.9 0.0 2.7 2 0 0 2 2 2 0 PAS domain Sec7 PF01369.15 CAR27741.1 - 0.034 13.8 0.1 0.066 12.8 0.1 1.4 1 0 0 1 1 1 0 Sec7 domain GET2 PF08690.5 CAR27741.1 - 0.24 10.6 4.8 1.2 8.3 3.0 2.0 2 0 0 2 2 2 0 GET complex subunit GET2 HEAT PF02985.17 CAR27742.1 - 1.9e-37 123.9 25.9 0.0029 17.5 0.1 13.0 14 0 0 14 14 14 10 HEAT repeat HEAT_2 PF13646.1 CAR27742.1 - 4e-30 103.9 0.9 4.2e-08 33.3 0.0 7.0 2 2 4 7 7 7 7 HEAT repeats HEAT_EZ PF13513.1 CAR27742.1 - 4.3e-09 36.5 7.3 4.4 7.9 0.0 8.3 9 1 1 10 10 10 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 CAR27742.1 - 1.8e-07 31.4 7.0 1.3 9.4 0.0 7.3 4 2 5 9 9 9 5 Vacuolar 14 Fab1-binding region Ecm29 PF13001.2 CAR27742.1 - 0.022 13.2 7.5 0.14 10.6 0.1 3.2 4 0 0 4 4 4 0 Proteasome stabiliser DUF2435 PF10363.4 CAR27742.1 - 0.67 9.8 11.4 1.6 8.6 0.4 4.6 4 1 1 5 5 5 0 Protein of unknown function (DUF2435) HhH-GPD PF00730.20 CAR27743.1 - 3e-25 88.5 0.0 4.7e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 CAR27743.1 - 0.00068 19.2 0.0 0.0018 17.8 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif Exo_endo_phos PF03372.18 CAR27744.1 - 3.8e-17 63.0 0.0 4.7e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SNARE PF05739.14 CAR27746.1 - 3.6e-09 36.1 1.5 3.6e-09 36.1 1.0 2.3 2 0 0 2 2 2 1 SNARE domain DUF1241 PF06840.6 CAR27746.1 - 0.0068 15.6 3.1 0.0071 15.6 0.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1241) CCDC84 PF14968.1 CAR27746.1 - 0.17 11.4 3.7 0.055 12.9 0.7 1.5 2 0 0 2 2 2 0 Coiled coil protein 84 PMC2NT PF08066.7 CAR27746.1 - 9.3 6.6 9.0 2.6 8.3 0.4 2.8 2 1 0 2 2 2 0 PMC2NT (NUC016) domain RRM_1 PF00076.17 CAR27747.1 - 2.1e-18 65.6 0.5 7.8e-15 54.2 0.0 3.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR27747.1 - 2.6e-14 52.9 0.2 2.6e-10 40.1 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR27747.1 - 2.2e-08 33.7 0.1 0.0036 17.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sds3 PF08598.6 CAR27748.1 - 6.4e-44 149.9 0.3 6.4e-44 149.9 0.2 2.3 2 1 0 2 2 2 1 Sds3-like Ribosomal_S19 PF00203.16 CAR27749.1 - 1.2e-30 104.9 0.2 1.7e-30 104.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_60s PF00428.14 CAR27750.1 - 2.8e-25 88.5 11.1 3.4e-25 88.2 7.7 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Cys_Met_Meta_PP PF01053.15 CAR27751.1 - 4.2e-144 479.5 0.0 4.8e-144 479.4 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.6 CAR27751.1 - 0.00017 20.0 0.0 0.00027 19.3 0.0 1.3 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_1_2 PF00155.16 CAR27751.1 - 0.0014 17.7 0.0 0.0021 17.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Hairpins PF04877.7 CAR27752.1 - 0.0049 16.3 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 HrpZ DUF775 PF05603.7 CAR27753.1 - 5.8e-59 199.0 0.0 6.6e-59 198.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) tRNA-synt_1c PF00749.16 CAR27754.1 - 1.1e-108 362.6 0.0 1.4e-108 362.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain zf-RING_2 PF13639.1 CAR27755.1 - 5.4e-11 42.1 4.4 5.8e-10 38.8 0.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 CAR27755.1 - 1.5e-06 28.2 1.4 7.9e-05 22.6 0.4 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CAR27755.1 - 1.1e-05 25.3 5.9 3.6e-05 23.6 1.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CAR27755.1 - 1.5e-05 24.5 3.1 4.2e-05 23.1 0.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAR27755.1 - 5.5e-05 22.8 3.2 0.00045 19.8 0.4 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CAR27755.1 - 0.00015 21.4 0.6 0.00015 21.4 0.4 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CAR27755.1 - 0.00019 21.2 1.4 0.00019 21.2 1.0 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 CAR27755.1 - 0.00027 20.5 4.5 0.0013 18.3 0.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 CAR27755.1 - 0.0028 17.1 0.1 0.0063 16.0 0.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 CAR27755.1 - 0.029 14.1 0.7 0.11 12.3 0.2 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger WD40 PF00400.27 CAR27756.1 - 2.9e-25 87.1 17.6 1.7e-06 27.7 0.5 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat BBS2_Mid PF14783.1 CAR27756.1 - 0.053 13.2 0.0 11 5.7 0.0 2.3 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.1 CAR27756.1 - 0.19 12.0 0.8 21 5.5 0.3 3.5 4 0 0 4 4 4 0 PQQ-like domain Mod_r PF07200.8 CAR27757.1 - 2.6e-23 82.6 11.4 3e-23 82.3 7.9 1.0 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Filament PF00038.16 CAR27757.1 - 0.0019 17.7 9.9 0.0036 16.8 6.9 1.5 1 1 0 1 1 1 1 Intermediate filament protein APG6 PF04111.7 CAR27757.1 - 0.0056 15.7 9.3 0.0074 15.3 6.4 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 HALZ PF02183.13 CAR27757.1 - 0.0059 16.2 3.9 0.0072 16.0 0.5 2.7 2 0 0 2 2 2 1 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.7 CAR27757.1 - 0.013 15.2 9.0 0.027 14.2 6.3 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Med10 PF09748.4 CAR27757.1 - 0.023 14.5 1.7 0.054 13.3 1.2 1.8 1 1 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex DUF4140 PF13600.1 CAR27757.1 - 0.026 14.9 2.3 0.073 13.5 0.4 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Retrotrans_gag PF03732.12 CAR27757.1 - 0.043 13.8 5.8 0.058 13.4 0.7 2.5 1 1 1 2 2 2 0 Retrotransposon gag protein CENP-F_leu_zip PF10473.4 CAR27757.1 - 0.055 13.3 10.7 0.36 10.6 7.2 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TBPIP PF07106.8 CAR27757.1 - 0.064 12.8 7.0 0.03 13.8 2.8 1.7 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Seryl_tRNA_N PF02403.17 CAR27757.1 - 0.065 13.2 1.0 0.065 13.2 0.7 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1053 PF06327.9 CAR27757.1 - 0.067 13.5 1.3 1.7 9.0 0.9 2.8 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1053) End3 PF12761.2 CAR27757.1 - 0.07 12.7 5.3 0.094 12.3 3.7 1.3 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF4200 PF13863.1 CAR27757.1 - 0.079 12.9 8.3 0.67 9.9 2.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Med4 PF10018.4 CAR27757.1 - 0.091 12.1 7.4 0.15 11.4 5.0 1.5 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 V_ATPase_I PF01496.14 CAR27757.1 - 0.094 10.5 1.4 0.1 10.4 1.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2407_C PF13373.1 CAR27757.1 - 0.1 12.5 1.9 0.16 11.9 1.3 1.3 1 0 0 1 1 1 0 DUF2407 C-terminal domain Rab5-bind PF09311.6 CAR27757.1 - 0.1 12.4 12.6 0.14 12.0 8.6 1.4 1 1 0 1 1 1 0 Rabaptin-like protein WXG100 PF06013.7 CAR27757.1 - 0.11 12.5 3.6 1.6 8.8 0.3 2.9 1 1 2 3 3 3 0 Proteins of 100 residues with WXG FliJ PF02050.11 CAR27757.1 - 0.12 12.4 13.4 0.051 13.6 7.7 1.6 2 0 0 2 2 1 0 Flagellar FliJ protein PilJ PF13675.1 CAR27757.1 - 0.12 12.6 3.4 0.23 11.7 2.3 1.6 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Rotamase PF00639.16 CAR27757.1 - 0.15 12.7 0.5 0.29 11.8 0.3 1.7 1 1 0 1 1 1 0 PPIC-type PPIASE domain Cep57_CLD_2 PF14197.1 CAR27757.1 - 0.16 11.9 8.5 0.37 10.7 4.6 2.6 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Occludin_ELL PF07303.8 CAR27757.1 - 0.16 12.6 9.6 0.43 11.3 5.5 1.9 1 1 1 2 2 2 0 Occludin homology domain Fib_alpha PF08702.5 CAR27757.1 - 0.17 11.9 5.0 0.27 11.3 3.4 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF607 PF04678.8 CAR27757.1 - 0.17 11.7 1.4 0.21 11.5 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF607 DASH_Dad3 PF08656.5 CAR27757.1 - 0.18 11.5 4.4 0.51 10.0 1.0 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad3 FlxA PF14282.1 CAR27757.1 - 0.32 10.9 10.8 1.1 9.2 7.5 1.8 1 1 0 1 1 1 0 FlxA-like protein Phage_GP20 PF06810.6 CAR27757.1 - 0.35 10.3 8.9 0.64 9.4 6.1 1.5 1 1 0 1 1 1 0 Phage minor structural protein GP20 Syntaxin PF00804.20 CAR27757.1 - 0.46 10.6 5.6 0.34 11.0 2.3 1.9 1 1 1 2 2 2 0 Syntaxin IncA PF04156.9 CAR27757.1 - 0.47 10.0 14.9 0.87 9.1 10.3 1.5 1 1 0 1 1 1 0 IncA protein bZIP_2 PF07716.10 CAR27757.1 - 0.57 10.0 4.3 0.55 10.0 0.9 2.4 2 0 0 2 2 2 0 Basic region leucine zipper Spc24 PF08286.6 CAR27757.1 - 0.58 9.8 5.9 1.4 8.6 4.1 1.8 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Med9 PF07544.8 CAR27757.1 - 0.8 9.4 6.3 0.25 11.1 1.6 2.0 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF342 PF03961.8 CAR27757.1 - 0.84 7.9 6.5 1.4 7.2 4.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Tropomyosin_1 PF12718.2 CAR27757.1 - 1.4 8.7 10.4 15 5.3 7.0 2.0 1 1 1 2 2 2 0 Tropomyosin like Surfac_D-trimer PF09006.6 CAR27757.1 - 1.5 8.6 6.1 1.5 8.6 0.4 2.8 3 0 0 3 3 2 0 Lung surfactant protein D coiled-coil trimerisation Fzo_mitofusin PF04799.8 CAR27757.1 - 1.7 8.0 6.1 1.2 8.4 1.5 2.1 1 1 1 2 2 2 0 fzo-like conserved region OmpH PF03938.9 CAR27757.1 - 1.7 8.5 7.6 2.3 8.1 5.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TMF_DNA_bd PF12329.3 CAR27757.1 - 1.9 8.3 8.3 1.2 8.9 3.2 2.3 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 CAR27757.1 - 2 7.9 7.2 0.37 10.3 1.3 2.4 1 1 2 3 3 3 0 Septum formation initiator H-kinase_dim PF02895.9 CAR27757.1 - 2 8.8 6.4 30 5.0 4.4 2.3 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain AKNA PF12443.3 CAR27757.1 - 2 8.4 9.3 1.4 8.9 3.7 2.4 1 1 0 2 2 2 0 AT-hook-containing transcription factor Jnk-SapK_ap_N PF09744.4 CAR27757.1 - 2.1 8.3 11.3 4.2 7.3 6.6 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 bZIP_1 PF00170.16 CAR27757.1 - 2.4 8.1 6.7 0.8 9.7 1.2 2.5 2 1 1 3 3 2 0 bZIP transcription factor Abhydrolase_2 PF02230.11 CAR27758.1 - 6.7e-53 179.3 0.0 7.6e-53 179.1 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 CAR27758.1 - 3.3e-14 52.8 0.0 4.1e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 CAR27758.1 - 2.3e-09 37.0 0.0 5.3e-09 35.8 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 CAR27758.1 - 2.3e-08 34.1 0.0 2.8e-06 27.3 0.0 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CAR27758.1 - 2e-05 23.9 0.1 0.00065 18.9 0.0 2.5 3 0 0 3 3 3 1 Prolyl oligopeptidase family DLH PF01738.13 CAR27758.1 - 5e-05 22.6 0.0 0.0012 18.1 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.7 CAR27758.1 - 0.0086 14.6 0.0 0.015 13.8 0.0 1.4 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.8 CAR27758.1 - 0.027 14.0 0.3 0.087 12.3 0.0 1.8 1 1 0 2 2 2 0 alpha/beta hydrolase fold DUF2974 PF11187.3 CAR27758.1 - 0.048 13.0 0.0 0.095 12.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Dopey_N PF04118.9 CAR27759.1 - 3.7e-119 397.0 0.2 1.5e-118 395.1 0.1 2.1 1 0 0 1 1 1 1 Dopey, N-terminal ENTH PF01417.15 CAR27759.1 - 0.019 14.8 1.3 0.17 11.7 0.1 3.1 3 0 0 3 3 3 0 ENTH domain Methyltransf_26 PF13659.1 CAR27760.1 - 1.5e-15 57.2 0.0 2.1e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CAR27760.1 - 1.6e-07 30.8 0.0 1.9e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 CAR27760.1 - 3.3e-07 30.0 0.0 4.1e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAR27760.1 - 0.001 19.4 0.0 0.0034 17.7 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 CAR27760.1 - 0.0045 16.1 0.0 0.038 13.0 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 CAR27760.1 - 0.0054 16.4 0.0 0.028 14.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAR27760.1 - 0.017 15.5 0.0 0.09 13.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Met_10 PF02475.11 CAR27760.1 - 0.07 12.7 0.0 0.094 12.2 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein ubiquitin PF00240.18 CAR27761.1 - 3e-22 77.7 0.4 3.3e-22 77.6 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CAR27761.1 - 4.2e-15 55.1 0.3 4.6e-15 55.0 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CAR27761.1 - 0.00085 19.5 0.1 0.0027 17.9 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain TUG-UBL1 PF11470.3 CAR27761.1 - 0.023 14.6 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 GLUT4 regulating protein TUG TPR_14 PF13428.1 CAR27762.1 - 3.6e-20 70.6 1.0 0.096 13.3 0.0 9.7 6 2 6 12 12 11 5 Tetratricopeptide repeat HAT PF02184.11 CAR27762.1 - 2.9e-15 55.6 33.7 0.0026 17.4 0.4 9.6 10 0 0 10 10 10 5 HAT (Half-A-TPR) repeat TPR_16 PF13432.1 CAR27762.1 - 6.3e-14 52.1 0.0 0.0093 16.6 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat Suf PF05843.9 CAR27762.1 - 2.3e-13 50.5 15.1 0.0007 19.4 0.2 6.3 3 3 3 7 7 7 4 Suppressor of forked protein (Suf) TPR_19 PF14559.1 CAR27762.1 - 8.2e-11 42.0 0.0 0.049 13.9 0.0 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 CAR27762.1 - 1.3e-09 37.2 2.1 15 5.8 0.0 7.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_17 PF13431.1 CAR27762.1 - 1.3e-06 28.1 1.3 0.022 14.9 0.0 4.2 5 0 0 5 5 4 2 Tetratricopeptide repeat U3_assoc_6 PF08640.6 CAR27762.1 - 1.5e-06 27.8 21.4 0.0041 16.8 2.0 6.6 5 2 2 7 7 7 2 U3 small nucleolar RNA-associated protein 6 TPR_7 PF13176.1 CAR27762.1 - 2.4e-06 26.9 2.3 5 7.1 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 CAR27762.1 - 2.9e-06 26.8 2.1 0.49 10.0 0.0 5.0 5 1 0 5 5 5 2 TPR repeat TPR_8 PF13181.1 CAR27762.1 - 4.7e-06 25.9 1.2 4.9 7.1 0.0 6.2 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 CAR27762.1 - 1.3e-05 25.0 3.9 1.5 8.7 0.0 6.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_15 PF13429.1 CAR27762.1 - 0.00057 19.0 1.3 0.0051 15.8 0.3 4.1 4 2 3 7 7 7 3 Tetratricopeptide repeat zf-CCHC_3 PF13917.1 CAR27763.1 - 7.5e-06 25.5 4.3 0.0019 17.8 0.2 2.6 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC PF00098.18 CAR27763.1 - 2.7e-05 23.8 6.8 0.00071 19.3 0.1 2.3 2 0 0 2 2 2 2 Zinc knuckle KH_3 PF13014.1 CAR27763.1 - 4.4e-05 23.0 0.1 9.9e-05 21.8 0.1 1.6 1 0 0 1 1 1 1 KH domain KH_1 PF00013.24 CAR27763.1 - 6e-05 22.5 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC_4 PF14392.1 CAR27763.1 - 0.13 11.9 4.5 0.78 9.4 0.3 2.4 2 0 0 2 2 2 0 Zinc knuckle DUF1660 PF07874.6 CAR27763.1 - 0.21 11.9 0.3 0.42 10.9 0.2 1.5 1 0 0 1 1 1 0 Prophage protein (DUF1660) CPSF100_C PF13299.1 CAR27764.1 - 4.6e-38 130.9 0.4 4.6e-38 130.9 0.2 2.0 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 CAR27764.1 - 3.7e-11 43.0 0.0 1e-10 41.6 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain efThoc1 PF11957.3 CAR27766.1 - 5.1e-88 295.7 17.1 5.1e-88 295.7 11.9 1.7 2 0 0 2 2 2 1 THO complex subunit 1 transcription elongation factor Avl9 PF09794.4 CAR27767.1 - 1.4e-142 474.7 0.4 2.2e-142 474.0 0.3 1.3 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 CAR27767.1 - 7.3e-06 25.6 0.8 0.15 11.7 0.0 3.0 3 0 0 3 3 3 2 Stabilization of polarity axis DUF2347 PF09804.4 CAR27767.1 - 0.0027 17.0 14.4 0.027 13.7 0.0 3.9 3 2 0 3 3 3 2 Uncharacterized conserved protein (DUF2347) DENN PF02141.16 CAR27767.1 - 0.086 12.5 0.6 2.1 8.0 0.1 2.5 2 0 0 2 2 2 0 DENN (AEX-3) domain CDC27 PF09507.5 CAR27767.1 - 1.1 8.3 24.2 1.7 7.7 16.7 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Rgp1 PF08737.5 CAR27768.1 - 1.3e-84 284.6 3.1 1.9e-84 284.1 2.1 1.2 1 0 0 1 1 1 1 Rgp1 Arrestin_C PF02752.17 CAR27768.1 - 0.017 15.1 0.0 14 5.8 0.0 3.3 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain ABC_membrane PF00664.18 CAR27769.1 - 2.7e-90 302.5 28.4 3.6e-49 167.6 4.0 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CAR27769.1 - 1.3e-49 167.9 0.1 6.1e-30 104.3 0.0 2.9 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CAR27769.1 - 7.5e-09 35.1 5.0 0.0036 16.5 0.2 4.2 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CAR27769.1 - 5.4e-08 33.0 0.2 0.0047 16.9 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 CAR27769.1 - 1.7e-05 24.7 0.2 0.25 11.3 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 CAR27769.1 - 0.00014 21.3 0.2 0.52 9.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 CAR27769.1 - 0.00015 21.2 0.1 0.49 9.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 CAR27769.1 - 0.00021 21.7 0.7 0.65 10.4 0.0 3.3 3 0 0 3 3 2 2 Miro-like protein AAA_23 PF13476.1 CAR27769.1 - 0.00099 19.4 6.0 0.06 13.6 0.0 3.2 3 1 0 3 3 3 1 AAA domain AAA_21 PF13304.1 CAR27769.1 - 0.001 19.0 10.4 1.6 8.6 0.0 5.5 3 2 1 4 4 4 2 AAA domain DUF258 PF03193.11 CAR27769.1 - 0.0016 17.6 0.1 0.64 9.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CAR27769.1 - 0.0026 17.6 2.1 0.19 11.5 0.0 3.4 3 0 0 3 3 3 1 Dynamin family UPF0093 PF03653.8 CAR27769.1 - 0.0032 17.4 2.3 0.005 16.7 0.2 2.3 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0093) AAA_10 PF12846.2 CAR27769.1 - 0.0037 16.7 1.7 3.2 7.0 0.0 3.3 2 1 0 3 3 3 1 AAA-like domain DUF87 PF01935.12 CAR27769.1 - 0.0084 15.9 4.9 0.18 11.5 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 CAR27769.1 - 0.01 15.3 0.0 3.6 7.0 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.1 CAR27769.1 - 0.02 15.0 0.4 7.9 6.6 0.0 3.0 2 1 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 CAR27769.1 - 0.032 12.8 0.3 1.4 7.4 0.0 2.7 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain AAA_17 PF13207.1 CAR27769.1 - 0.035 14.9 0.1 4.5 8.1 0.0 3.0 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.11 CAR27769.1 - 0.046 12.8 0.7 1 8.4 0.0 2.6 2 0 0 2 2 2 0 AIG1 family AAA_18 PF13238.1 CAR27769.1 - 0.058 13.7 0.0 7.1 6.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 CAR27769.1 - 0.058 13.0 1.6 5.3 6.7 0.0 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 CAR27769.1 - 0.083 11.7 0.0 0.55 9.0 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 CAR27769.1 - 0.14 11.2 0.2 7.9 5.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.1 CAR27769.1 - 0.17 11.4 0.5 13 5.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain Pkinase PF00069.20 CAR27770.1 - 6.5e-69 231.9 0.0 9.2e-69 231.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR27770.1 - 4.3e-30 104.6 0.0 6.3e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CAR27770.1 - 1.5e-05 24.1 0.1 5.4e-05 22.3 0.1 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CAR27770.1 - 0.00028 20.7 0.7 0.0018 18.0 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CAR27770.1 - 0.0031 16.5 0.0 0.061 12.2 0.0 2.2 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 CAR27770.1 - 0.084 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Flocculin_t3 PF13928.1 CAR27771.1 - 2.4e-13 49.9 14.7 2.4e-13 49.9 10.2 3.9 3 1 0 3 3 3 1 Flocculin type 3 repeat Gram_pos_anchor PF00746.16 CAR27771.1 - 8.2 6.3 8.1 2.4 8.0 1.5 2.5 2 0 0 2 2 2 0 Gram positive anchor Redoxin PF08534.5 CAR27772.1 - 1.6e-26 92.5 0.1 1.9e-26 92.3 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 CAR27772.1 - 7.9e-09 35.2 0.0 1e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Hydrolase PF00702.21 CAR27772.1 - 0.018 15.4 0.0 0.02 15.2 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD PF12710.2 CAR27772.1 - 0.1 12.7 0.0 0.29 11.2 0.0 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase BTB_2 PF02214.17 CAR27773.1 - 2.4e-09 37.2 0.2 3.3e-05 24.0 0.1 2.8 2 1 0 2 2 2 2 BTB/POZ domain DUF3760 PF12586.3 CAR27774.1 - 0.2 11.5 0.2 0.2 11.5 0.1 2.6 3 1 1 4 4 4 0 Protein of unknown function (DUF3760) Flg_hook PF02120.11 CAR27775.1 - 0.0062 16.1 0.2 0.011 15.3 0.2 1.4 1 0 0 1 1 1 1 Flagellar hook-length control protein FliK V_ATPase_I PF01496.14 CAR27775.1 - 3.3 5.4 11.2 4 5.1 7.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Seryl_tRNA_N PF02403.17 CAR27775.1 - 4.1 7.4 14.5 6.7 6.7 10.1 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF342 PF03961.8 CAR27775.1 - 4.3 5.6 8.4 5.3 5.3 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) RNase_T PF00929.19 CAR27776.1 - 6.3e-17 62.3 0.1 1.4e-16 61.2 0.1 1.6 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 CAR27776.1 - 0.011 15.2 0.1 0.048 13.1 0.0 2.2 2 1 0 2 2 2 0 3'-5' exonuclease CHORD PF04968.7 CAR27776.1 - 0.084 13.1 6.0 0.16 12.2 4.2 1.4 1 0 0 1 1 1 0 CHORD DUF2650 PF10853.3 CAR27776.1 - 0.11 11.9 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2650) AAA_5 PF07728.9 CAR27777.1 - 3.2e-126 415.7 1.0 1.2e-20 73.6 0.0 9.9 10 0 0 10 10 9 9 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CAR27777.1 - 1.1e-31 109.1 0.0 5.7e-11 42.1 0.0 7.7 8 0 0 8 8 8 3 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CAR27777.1 - 2.4e-24 86.4 0.0 0.019 15.7 0.0 7.9 6 0 0 6 6 6 5 AAA domain AAA PF00004.24 CAR27777.1 - 5.4e-24 84.8 1.7 0.0024 18.0 0.0 7.9 7 0 0 7 7 7 5 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 CAR27777.1 - 5.1e-23 81.6 0.8 1.9e-05 24.7 0.0 7.9 8 0 0 8 8 7 3 Sigma-54 interaction domain Sigma54_activat PF00158.21 CAR27777.1 - 3e-20 72.3 0.1 0.00025 20.5 0.0 6.5 7 0 0 7 7 6 5 Sigma-54 interaction domain AAA_14 PF13173.1 CAR27777.1 - 6.5e-20 71.3 1.3 0.00029 20.7 0.0 8.9 8 1 1 9 9 8 4 AAA domain AAA_22 PF13401.1 CAR27777.1 - 3e-17 62.9 1.6 0.021 14.9 0.0 7.8 7 0 0 7 7 7 3 AAA domain T2SE PF00437.15 CAR27777.1 - 1.1e-16 60.5 2.8 0.018 13.9 0.4 5.9 6 0 0 6 6 6 5 Type II/IV secretion system protein ABC_tran PF00005.22 CAR27777.1 - 1.7e-15 57.5 14.8 0.00011 22.5 0.2 7.7 7 0 0 7 7 6 3 ABC transporter AAA_33 PF13671.1 CAR27777.1 - 1e-14 54.6 0.2 0.061 13.2 0.0 7.1 7 0 0 7 7 6 3 AAA domain AAA_16 PF13191.1 CAR27777.1 - 1.7e-13 50.9 18.4 0.0039 17.2 0.1 8.0 8 1 0 8 8 5 4 AAA ATPase domain Miro PF08477.8 CAR27777.1 - 6.3e-13 49.2 2.2 1.3 9.5 0.0 6.8 6 0 0 6 6 6 3 Miro-like protein DUF258 PF03193.11 CAR27777.1 - 1e-11 44.3 5.9 0.093 11.9 0.0 6.4 6 0 0 6 6 6 4 Protein of unknown function, DUF258 AAA_19 PF13245.1 CAR27777.1 - 1e-11 44.3 2.7 0.045 13.5 0.0 5.6 5 0 0 5 5 5 3 Part of AAA domain RNA_helicase PF00910.17 CAR27777.1 - 1.6e-11 44.2 3.1 0.18 11.9 0.0 7.3 7 0 0 7 7 6 2 RNA helicase UPF0079 PF02367.12 CAR27777.1 - 3.7e-11 42.7 2.3 0.18 11.4 0.0 6.0 6 0 0 6 6 5 3 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 CAR27777.1 - 9.7e-11 41.0 0.3 0.47 10.0 0.0 6.4 6 0 0 6 6 6 1 P-loop containing region of AAA domain NACHT PF05729.7 CAR27777.1 - 9.3e-10 38.4 3.2 0.13 11.9 0.0 5.5 5 0 0 5 5 4 3 NACHT domain Mg_chelatase PF01078.16 CAR27777.1 - 3.5e-09 36.1 3.1 4.8 6.2 0.0 8.4 8 1 1 9 9 9 0 Magnesium chelatase, subunit ChlI PduV-EutP PF10662.4 CAR27777.1 - 3.5e-09 36.2 2.4 0.039 13.4 0.0 5.6 6 0 0 6 6 5 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 CAR27777.1 - 3.9e-09 36.4 0.9 12 5.8 0.0 6.8 6 0 0 6 6 6 0 50S ribosome-binding GTPase AAA_18 PF13238.1 CAR27777.1 - 4e-09 36.8 31.0 0.017 15.4 0.0 9.7 9 1 0 9 9 6 3 AAA domain MobB PF03205.9 CAR27777.1 - 5.8e-09 35.7 6.2 0.12 12.0 0.2 6.9 6 0 0 6 6 6 2 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 CAR27777.1 - 1.3e-08 34.4 0.4 0.36 10.2 0.0 5.5 6 0 0 6 6 6 2 IstB-like ATP binding protein AAA_25 PF13481.1 CAR27777.1 - 4.8e-08 32.6 2.8 0.61 9.4 0.0 5.7 5 0 0 5 5 5 2 AAA domain AAA_28 PF13521.1 CAR27777.1 - 7.7e-08 32.4 5.4 3.9 7.4 0.0 6.3 5 0 0 5 5 5 0 AAA domain AAA_7 PF12775.2 CAR27777.1 - 1.1e-07 31.2 0.4 0.18 10.8 0.0 4.7 5 0 0 5 5 5 2 P-loop containing dynein motor region D3 SRP54 PF00448.17 CAR27777.1 - 8.3e-07 28.6 6.9 0.18 11.2 0.0 5.0 5 0 0 5 5 4 2 SRP54-type protein, GTPase domain RuvB_N PF05496.7 CAR27777.1 - 2.8e-06 26.5 0.8 1.9 7.4 0.0 5.6 5 0 0 5 5 5 1 Holliday junction DNA helicase ruvB N-terminus PhoH PF02562.11 CAR27777.1 - 5.6e-05 22.4 0.6 1.5 8.0 0.0 4.8 5 0 0 5 5 4 1 PhoH-like protein ATP-synt_ab PF00006.20 CAR27777.1 - 8.2e-05 22.2 0.0 1.8 8.0 0.0 3.9 3 1 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain CPT PF07931.7 CAR27777.1 - 0.00017 21.2 0.3 15 5.1 0.0 6.0 5 1 0 5 5 5 0 Chloramphenicol phosphotransferase-like protein DEAD PF00270.24 CAR27777.1 - 0.0002 20.8 0.3 4.3 6.8 0.0 4.5 4 0 0 4 4 4 0 DEAD/DEAH box helicase ATP_bind_1 PF03029.12 CAR27777.1 - 0.00046 19.8 9.0 5.1 6.5 0.1 6.2 6 0 0 6 6 6 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.10 CAR27777.1 - 0.00061 19.5 6.0 2.6 7.7 0.3 5.9 5 0 0 5 5 5 1 NTPase AAA_23 PF13476.1 CAR27777.1 - 0.002 18.4 2.1 0.002 18.4 1.5 11.5 11 1 1 12 12 5 3 AAA domain KaiC PF06745.8 CAR27777.1 - 0.013 14.6 8.8 8.8 5.3 0.0 5.5 6 0 0 6 6 5 0 KaiC AAA_6 PF12774.2 CAR27777.1 - 0.024 14.1 0.0 10 5.5 0.0 4.2 4 0 0 4 4 4 0 Hydrolytic ATP binding site of dynein motor region D1 ArgK PF03308.11 CAR27777.1 - 0.042 12.6 1.2 23 3.6 0.1 3.4 3 0 0 3 3 3 0 ArgK protein CbiA PF01656.18 CAR27777.1 - 0.1 11.9 6.7 0.3 10.4 0.0 4.3 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain FtsK_SpoIIIE PF01580.13 CAR27777.1 - 0.15 11.5 6.4 5.5 6.4 0.0 4.8 6 0 0 6 6 4 0 FtsK/SpoIIIE family tRNA_int_endo PF01974.12 CAR27778.1 - 2.7e-23 81.5 0.1 5.8e-23 80.4 0.1 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 CAR27778.1 - 0.003 17.0 0.0 0.38 10.3 0.0 2.8 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain Pox_D5 PF03288.11 CAR27778.1 - 0.046 13.9 1.3 7.2 6.9 0.1 2.7 2 0 0 2 2 2 0 Poxvirus D5 protein-like ERM PF00769.14 CAR27778.1 - 0.075 12.5 7.2 0.11 12.0 5.0 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family CDC45 PF02724.9 CAR27780.1 - 9.5e-211 701.0 0.5 1.1e-210 700.8 0.3 1.0 1 0 0 1 1 1 1 CDC45-like protein DUF4611 PF15387.1 CAR27780.1 - 0.004 17.2 10.9 0.0045 17.0 6.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.5 CAR27780.1 - 0.016 15.4 11.3 0.036 14.2 7.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.8 CAR27780.1 - 0.061 12.9 8.2 0.1 12.2 5.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop53 PF07767.6 CAR27780.1 - 0.2 10.5 10.9 0.31 9.9 7.6 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Nucleoplasmin PF03066.10 CAR27780.1 - 0.52 9.8 9.0 0.99 8.9 6.3 1.4 1 0 0 1 1 1 0 Nucleoplasmin TFIIF_alpha PF05793.7 CAR27780.1 - 0.86 7.8 11.7 1.5 7.1 8.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Apc9 PF12856.2 CAR27781.1 - 1.7e-22 79.4 0.0 2.6e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 9 CH PF00307.26 CAR27782.1 - 1.7e-69 230.7 0.4 5.9e-20 71.3 0.1 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 CAR27782.1 - 0.00019 21.0 0.1 1.4 8.5 0.0 3.6 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_7 PF13499.1 CAR27782.1 - 0.0055 16.8 0.3 0.11 12.6 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair adh_short PF00106.20 CAR27783.1 - 1.7e-06 28.0 0.0 0.0008 19.3 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 CAR27783.1 - 0.089 12.4 0.0 0.24 11.0 0.0 1.7 2 0 0 2 2 2 0 KR domain WD40 PF00400.27 CAR27784.1 - 1.2e-13 50.3 25.5 1.7e-06 27.6 0.0 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat RWD PF05773.17 CAR27784.1 - 0.00011 22.0 0.2 0.00035 20.4 0.0 1.9 2 0 0 2 2 2 1 RWD domain C1_3 PF07649.7 CAR27784.1 - 0.037 14.0 6.2 0.084 12.9 4.3 1.7 1 0 0 1 1 1 0 C1-like domain zf-RING_2 PF13639.1 CAR27784.1 - 0.95 9.3 11.9 2.3 8.0 8.2 1.7 1 0 0 1 1 1 0 Ring finger domain EPSP_synthase PF00275.15 CAR27785.1 - 1.5e-135 451.9 0.0 2.1e-135 451.4 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 CAR27785.1 - 8e-98 326.5 0.0 1.3e-97 325.8 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 CAR27785.1 - 1.2e-64 218.0 0.0 1.9e-64 217.3 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 CAR27785.1 - 4.4e-34 117.6 0.0 5e-33 114.2 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 CAR27785.1 - 1.3e-20 73.1 0.0 5.2e-20 71.2 0.0 2.1 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 CAR27785.1 - 6.7e-16 58.6 0.0 3.1e-15 56.4 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 CAR27785.1 - 1.3e-07 31.1 0.0 3.3e-07 29.8 0.0 1.7 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 CAR27785.1 - 0.00024 21.9 0.0 0.00078 20.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CAR27785.1 - 0.034 14.0 0.0 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain THF_DHG_CYH PF00763.18 CAR27785.1 - 0.098 12.6 0.0 0.33 11.0 0.0 1.8 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain zf-DHHC PF01529.15 CAR27786.1 - 4.2e-28 97.9 14.4 4.2e-28 97.9 10.0 2.2 1 1 1 2 2 2 1 DHHC palmitoyltransferase FYVE_2 PF02318.11 CAR27786.1 - 4 7.3 8.3 0.77 9.6 0.1 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger DUF1925 PF09094.6 CAR27787.1 - 0.093 12.7 0.1 4 7.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1925) Abhydrolase_6 PF12697.2 CAR27789.1 - 7.8e-21 75.0 0.0 1.1e-20 74.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAR27789.1 - 3e-13 49.8 0.0 2.9e-08 33.5 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CAR27789.1 - 4.9e-12 45.8 0.0 9.5e-12 44.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 CAR27789.1 - 2.3e-07 30.1 0.2 8.6e-06 25.0 0.4 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.15 CAR27789.1 - 6.5e-05 23.2 0.0 0.00032 20.9 0.0 2.0 2 0 0 2 2 2 1 Thioesterase domain Esterase PF00756.15 CAR27789.1 - 0.00025 20.5 0.0 0.00042 19.8 0.0 1.3 1 0 0 1 1 1 1 Putative esterase DUF2305 PF10230.4 CAR27789.1 - 0.013 14.9 0.0 0.039 13.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) DLH PF01738.13 CAR27789.1 - 0.04 13.1 0.0 0.067 12.4 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Ndr PF03096.9 CAR27789.1 - 0.042 12.3 0.0 0.11 11.0 0.0 1.6 2 0 0 2 2 2 0 Ndr family Abhydrolase_3 PF07859.8 CAR27789.1 - 0.068 12.7 0.0 0.19 11.2 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Fungal_trans PF04082.13 CAR27790.1 - 2.3e-35 121.7 2.8 2.3e-35 121.7 1.9 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR27790.1 - 8.5e-11 41.5 9.8 1.7e-10 40.6 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain gpW PF02831.10 CAR27790.1 - 0.099 12.2 0.0 0.27 10.8 0.0 1.7 1 0 0 1 1 1 0 gpW YwhD PF08741.5 CAR27790.1 - 0.11 11.8 0.2 0.27 10.6 0.1 1.5 1 0 0 1 1 1 0 YwhD family DUF2841 PF11001.3 CAR27791.1 - 2.8e-36 124.1 0.4 5.8e-36 123.1 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) F-box-like PF12937.2 CAR27792.1 - 7.3e-07 28.8 0.2 1.3e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CAR27792.1 - 0.0033 17.0 0.9 0.0067 16.0 0.6 1.4 1 0 0 1 1 1 1 F-box domain MIT PF04212.13 CAR27792.1 - 0.081 12.8 0.2 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain FliJ PF02050.11 CAR27792.1 - 0.15 12.1 2.4 0.3 11.1 1.7 1.4 1 0 0 1 1 1 0 Flagellar FliJ protein HLH PF00010.21 CAR27793.1 - 0.0024 17.5 0.3 0.0057 16.3 0.2 1.7 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain EF-hand_1 PF00036.27 CAR27793.1 - 0.32 10.4 5.8 0.35 10.2 3.1 1.9 2 0 0 2 2 2 0 EF hand EF-hand_5 PF13202.1 CAR27793.1 - 2.9 7.3 6.1 7.1 6.1 4.2 1.6 1 0 0 1 1 1 0 EF hand Pkinase PF00069.20 CAR27794.1 - 5.5e-72 242.0 0.6 5.5e-72 242.0 0.4 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR27794.1 - 2.5e-39 134.9 0.2 2.5e-39 134.9 0.1 3.0 2 1 0 2 2 2 1 Protein tyrosine kinase KA1 PF02149.14 CAR27794.1 - 6.7e-20 70.2 0.0 1.4e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 CAR27794.1 - 5.6e-06 25.5 0.0 5.6e-06 25.5 0.0 2.4 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CAR27794.1 - 4.3e-05 22.6 0.0 0.00012 21.2 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CAR27794.1 - 0.012 15.3 0.0 0.012 15.3 0.0 3.1 3 1 0 3 3 3 0 Phosphotransferase enzyme family WaaY PF06176.6 CAR27794.1 - 0.031 13.5 0.7 0.064 12.4 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide core biosynthesis protein (WaaY) PHD PF00628.24 CAR27795.1 - 0.006 16.2 1.8 0.006 16.2 1.3 2.2 3 0 0 3 3 3 1 PHD-finger Nyv1_N PF09426.5 CAR27797.1 - 1.1e-44 151.3 0.0 1.7e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 Vacuolar R-SNARE Nyv1 N terminal Synaptobrevin PF00957.16 CAR27797.1 - 1.3e-24 85.5 0.4 2e-24 84.9 0.3 1.2 1 0 0 1 1 1 1 Synaptobrevin PepSY_TM_2 PF13703.1 CAR27797.1 - 0.024 14.8 0.3 0.042 14.0 0.2 1.4 1 0 0 1 1 1 0 PepSY-associated TM helix DUF3484 PF11983.3 CAR27798.1 - 0.016 15.9 2.5 0.03 15.1 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3484) TRM PF02005.11 CAR27799.1 - 1.3e-143 478.5 0.0 1.6e-143 478.1 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 CAR27799.1 - 0.00012 21.7 0.1 0.00019 21.0 0.1 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.8 CAR27799.1 - 0.11 11.6 0.1 0.18 10.8 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) G-patch PF01585.18 CAR27801.1 - 2.8e-11 43.0 0.1 6.7e-11 41.7 0.1 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CAR27801.1 - 2.1e-06 27.4 0.1 2.1e-06 27.4 0.1 4.1 2 1 1 3 3 3 1 DExH-box splicing factor binding site SprA-related PF12118.3 CAR27801.1 - 0.01 15.1 19.2 0.012 14.9 13.3 1.1 1 0 0 1 1 1 0 SprA-related family RR_TM4-6 PF06459.7 CAR27801.1 - 0.037 13.9 25.8 0.053 13.4 17.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 YL1 PF05764.8 CAR27801.1 - 0.86 9.1 45.4 1.3 8.5 31.5 1.2 1 0 0 1 1 1 0 YL1 nuclear protein FLO_LFY PF01698.11 CAR27801.1 - 1.4 7.6 21.0 2 7.1 14.5 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Hex_IIIa PF02455.11 CAR27801.1 - 1.6 7.3 10.7 1.9 7.0 7.4 1.3 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Paf1 PF03985.8 CAR27801.1 - 2.6 6.6 30.5 3.5 6.2 21.1 1.1 1 0 0 1 1 1 0 Paf1 Hid1 PF12722.2 CAR27801.1 - 7.1 4.1 19.7 8.4 3.9 13.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MIP-T3 PF10243.4 CAR27801.1 - 7.8 4.8 53.1 11 4.3 36.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Glyco_hydro_72 PF03198.9 CAR27802.1 - 2.3e-144 480.1 10.6 3.3e-144 479.6 7.4 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 CAR27802.1 - 1.3e-27 96.0 7.2 4.5e-27 94.3 4.5 2.4 2 0 0 2 2 2 1 X8 domain Cellulase PF00150.13 CAR27802.1 - 0.00016 20.9 0.6 0.0012 18.0 0.4 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pex14_N PF04695.8 CAR27802.1 - 0.58 10.2 8.9 0.053 13.5 2.2 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Glucan_synthase PF02364.10 CAR27803.1 - 0 1369.4 1.0 0 1369.4 0.7 2.2 1 1 1 2 2 2 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 CAR27803.1 - 4.4e-36 123.3 0.7 4.4e-34 116.8 0.5 2.9 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glyco_hydro_17 PF00332.13 CAR27804.1 - 3.9e-10 39.2 0.3 5.5e-10 38.7 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 DUF566 PF04484.7 CAR27804.1 - 7.4 5.9 13.0 11 5.4 9.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) MA3 PF02847.12 CAR27805.1 - 9.2e-21 73.6 3.4 7.9e-20 70.6 0.1 3.1 2 1 1 3 3 3 1 MA3 domain MIF4G PF02854.14 CAR27805.1 - 2.4e-17 63.0 2.8 5.2e-17 61.9 1.9 1.6 1 0 0 1 1 1 1 MIF4G domain CTP_transf_2 PF01467.21 CAR27806.1 - 6.2e-15 55.5 0.0 8.8e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase USP7_C2 PF14533.1 CAR27807.1 - 2.6e-60 203.5 4.1 1.3e-58 197.9 0.2 3.3 3 1 0 3 3 3 2 Ubiquitin-specific protease C-terminal UCH PF00443.24 CAR27807.1 - 1.8e-51 174.8 1.6 2.9e-51 174.1 1.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.3 CAR27807.1 - 2.6e-35 121.8 0.4 1.4e-34 119.4 0.1 2.5 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.1 CAR27807.1 - 1.5e-31 109.9 0.0 2.3e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 CAR27807.1 - 1.4e-10 41.4 0.2 6e-10 39.3 0.1 2.2 1 0 0 1 1 1 1 MATH domain UN_NPL4 PF11543.3 CAR27807.1 - 0.00023 21.3 0.0 0.057 13.6 0.0 3.0 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 Telomere_Sde2 PF13019.1 CAR27807.1 - 0.096 12.3 0.0 3.9 7.1 0.0 3.0 3 0 0 3 3 3 0 Telomere stability and silencing RNA12 PF10443.4 CAR27808.1 - 1e-169 564.6 1.0 1e-169 564.6 0.7 2.1 2 0 0 2 2 2 1 RNA12 protein Arch_ATPase PF01637.13 CAR27808.1 - 1.2e-05 25.1 1.3 4.2e-05 23.3 0.1 2.5 2 1 0 2 2 2 1 Archaeal ATPase AAA_14 PF13173.1 CAR27808.1 - 3.8e-05 23.5 0.1 0.00049 19.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain RRM_1 PF00076.17 CAR27808.1 - 0.00019 21.0 0.0 0.00051 19.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_membrane PF00664.18 CAR27809.1 - 2.6e-37 128.7 11.7 3.3e-37 128.4 8.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 CAR27809.1 - 8.9e-34 116.7 0.1 4.7e-33 114.3 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 CAR27809.1 - 2.2e-10 41.0 0.0 7.1e-05 22.9 0.0 3.4 2 1 1 3 3 3 2 AAA domain SMC_N PF02463.14 CAR27809.1 - 7.5e-07 28.6 0.0 0.0011 18.3 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CAR27809.1 - 3e-05 24.0 0.0 7.3e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 CAR27809.1 - 0.00014 21.3 0.0 0.00026 20.5 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain AAA_17 PF13207.1 CAR27809.1 - 0.00039 21.2 0.3 0.0018 19.1 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CAR27809.1 - 0.00075 18.9 0.1 0.0018 17.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CAR27809.1 - 0.00092 19.3 0.1 0.0095 16.0 0.0 2.4 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.4 CAR27809.1 - 0.0014 17.3 0.0 0.14 10.7 0.0 2.3 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_25 PF13481.1 CAR27809.1 - 0.0015 17.9 0.1 0.0045 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 CAR27809.1 - 0.0087 15.2 0.0 0.017 14.3 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.1 CAR27809.1 - 0.015 15.2 0.0 0.19 11.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 CAR27809.1 - 0.038 13.7 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 CAR27809.1 - 0.043 13.0 0.0 0.24 10.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 CAR27809.1 - 0.044 14.1 6.0 0.68 10.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 CAR27809.1 - 0.052 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 CAR27809.1 - 0.064 13.4 0.0 0.46 10.6 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 CAR27809.1 - 0.074 12.9 0.3 0.4 10.6 0.2 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 CAR27809.1 - 0.1 12.1 0.0 0.42 10.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 CAR27809.1 - 0.14 11.8 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_24 PF13479.1 CAR27809.1 - 0.3 10.6 1.8 0.25 10.9 0.2 1.8 2 1 0 2 2 2 0 AAA domain GATase_2 PF00310.16 CAR27810.1 - 4e-25 88.2 0.0 4.3e-19 68.4 0.0 2.5 2 1 1 3 3 3 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 CAR27810.1 - 1.2e-14 54.3 0.0 3.3e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 CAR27810.1 - 9.3e-13 47.9 0.0 1.8e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_7 PF13537.1 CAR27810.1 - 9e-12 44.8 0.0 2.1e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 CAR27810.1 - 2.3e-06 26.5 0.0 3.7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II RNase_T PF00929.19 CAR27812.1 - 6e-24 85.1 0.2 1.7e-23 83.6 0.0 1.9 2 0 0 2 2 2 1 Exonuclease Rtt102p PF09510.5 CAR27813.1 - 1.1e-25 90.1 0.4 1.1e-25 90.1 0.3 2.0 2 1 0 2 2 2 1 Rtt102p-like transcription regulator protein Trypan_PARP PF05887.6 CAR27813.1 - 8e-05 22.4 17.5 0.00011 21.9 12.1 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) PAT1 PF09770.4 CAR27813.1 - 0.0029 15.9 23.6 0.0028 15.9 16.3 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Presenilin PF01080.12 CAR27813.1 - 1 8.1 7.8 1.3 7.8 5.4 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.7 CAR27813.1 - 1.8 8.4 12.2 2.3 8.0 8.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Suf PF05843.9 CAR27813.1 - 3.6 7.2 10.1 5.2 6.7 7.0 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Neisseria_TspB PF05616.8 CAR27813.1 - 6.7 4.9 15.7 8.3 4.6 10.9 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Herpes_DNAp_acc PF04929.7 CAR27813.1 - 8.3 5.2 8.0 9.5 5.0 5.6 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF3591 PF12157.3 CAR27814.1 - 3.1e-193 642.3 0.1 5.4e-193 641.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 CAR27814.1 - 3.4e-06 26.6 0.5 7.6e-06 25.4 0.4 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 CAR27814.1 - 0.19 11.7 0.3 0.52 10.3 0.2 1.8 1 0 0 1 1 1 0 Zinc knuckle Peptidase_S10 PF00450.17 CAR27816.1 - 2.6e-126 422.1 0.3 3.1e-126 421.8 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 CAR27816.1 - 2.4e-17 63.1 0.0 3.7e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Aminotran_1_2 PF00155.16 CAR27817.1 - 7.4e-60 202.8 0.0 8.9e-60 202.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF2406 PF10295.4 CAR27818.1 - 1.8e-24 85.9 0.0 3.5e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) DUF2361 PF10153.4 CAR27819.1 - 3.2e-30 104.6 14.4 1.5e-29 102.5 10.0 2.0 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2361) PhoU PF01895.14 CAR27819.1 - 1.4 9.3 4.4 1.5 9.3 1.2 2.1 1 1 1 2 2 2 0 PhoU domain Pox_A_type_inc PF04508.7 CAR27819.1 - 5.9 6.9 8.1 1.6 8.6 2.3 2.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Sec63 PF02889.11 CAR27820.1 - 1.9e-134 447.8 4.3 5.8e-91 304.9 0.1 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 CAR27820.1 - 2.3e-52 176.9 1.0 8e-28 97.0 0.4 4.0 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 CAR27820.1 - 1.6e-20 73.6 0.0 7.1e-10 39.0 0.1 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CAR27820.1 - 7.1e-17 61.0 0.1 4.5e-07 29.6 0.0 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain SNF2_N PF00176.18 CAR27820.1 - 2.4e-06 26.5 0.0 0.012 14.4 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain AAA_22 PF13401.1 CAR27820.1 - 6e-06 26.4 1.1 0.052 13.6 0.0 3.8 3 1 0 3 3 3 2 AAA domain PhoH PF02562.11 CAR27820.1 - 3.1e-05 23.2 0.0 0.013 14.7 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA PF00004.24 CAR27820.1 - 3.2e-05 24.1 0.0 0.16 12.2 0.0 4.1 3 2 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 CAR27820.1 - 4.7e-05 23.0 0.0 0.081 12.6 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain IstB_IS21 PF01695.12 CAR27820.1 - 0.00038 19.9 0.4 2 7.7 0.0 4.0 5 0 0 5 5 5 2 IstB-like ATP binding protein T2SE PF00437.15 CAR27820.1 - 0.0044 15.9 0.0 1.1 8.0 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_18 PF13238.1 CAR27820.1 - 0.0059 16.9 0.5 0.88 9.8 0.0 3.9 4 0 0 4 4 4 1 AAA domain AAA_10 PF12846.2 CAR27820.1 - 0.018 14.4 0.3 22 4.3 0.0 3.9 3 1 0 4 4 4 0 AAA-like domain Zeta_toxin PF06414.7 CAR27820.1 - 0.024 13.7 0.0 1.5 7.8 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin Dynamitin PF04912.9 CAR27821.1 - 1.8e-10 40.1 3.2 1.8e-10 40.1 2.2 2.2 2 0 0 2 2 2 2 Dynamitin Syntaxin-6_N PF09177.6 CAR27821.1 - 9.7 6.6 11.9 0.39 11.1 0.7 3.5 3 1 1 4 4 4 0 Syntaxin 6, N-terminal Amidase PF01425.16 CAR27822.1 - 2.2e-112 376.1 0.0 2.5e-112 375.9 0.0 1.0 1 0 0 1 1 1 1 Amidase AAA PF00004.24 CAR27823.1 - 1.3e-49 167.8 0.0 1.8e-42 144.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CAR27823.1 - 2.9e-07 30.5 0.0 4.4e-05 23.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 CAR27823.1 - 9.6e-07 28.3 0.0 3e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.1 CAR27823.1 - 9.8e-07 28.9 0.1 1.6e-05 24.9 0.0 3.0 3 1 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.1 CAR27823.1 - 3.5e-06 26.7 0.0 0.012 15.1 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 CAR27823.1 - 2.9e-05 24.2 0.1 0.0019 18.3 0.1 3.1 3 1 0 3 3 2 1 AAA domain Sigma54_activ_2 PF14532.1 CAR27823.1 - 6.9e-05 22.9 0.0 0.44 10.5 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.9 CAR27823.1 - 0.00027 20.6 0.0 0.0016 18.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CAR27823.1 - 0.00041 20.0 0.5 0.016 14.9 0.0 2.7 3 0 0 3 3 2 1 Part of AAA domain Bromodomain PF00439.20 CAR27823.1 - 0.0005 19.9 0.0 0.0013 18.6 0.0 1.7 1 0 0 1 1 1 1 Bromodomain AAA_14 PF13173.1 CAR27823.1 - 0.00089 19.1 0.0 0.028 14.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 CAR27823.1 - 0.0018 17.7 0.0 0.0047 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 CAR27823.1 - 0.0028 17.5 2.2 0.021 14.6 0.0 3.2 4 0 0 4 4 3 1 Type III restriction enzyme, res subunit AAA_18 PF13238.1 CAR27823.1 - 0.0029 17.9 0.0 0.15 12.3 0.0 3.5 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.1 CAR27823.1 - 0.0049 17.6 2.1 0.039 14.7 0.0 3.6 3 1 0 3 3 2 1 AAA domain TIP49 PF06068.8 CAR27823.1 - 0.0057 15.4 0.0 0.015 14.0 0.0 1.6 2 0 0 2 2 2 1 TIP49 C-terminus PhoH PF02562.11 CAR27823.1 - 0.011 14.9 0.0 0.14 11.3 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activat PF00158.21 CAR27823.1 - 0.013 14.9 0.0 1.5 8.2 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_33 PF13671.1 CAR27823.1 - 0.013 15.3 0.0 0.039 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 CAR27823.1 - 0.017 14.2 0.1 0.14 11.3 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 CAR27823.1 - 0.021 14.9 0.0 0.079 13.1 0.0 2.1 2 0 0 2 2 1 0 RNA helicase Parvo_NS1 PF01057.12 CAR27823.1 - 0.035 12.9 0.0 0.58 8.9 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 RuvB_N PF05496.7 CAR27823.1 - 0.063 12.3 0.0 0.13 11.2 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_3 PF07726.6 CAR27823.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Got1 PF04178.7 CAR27824.1 - 1.5e-19 70.2 13.1 1.7e-19 70.0 9.1 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF973 PF06157.6 CAR27824.1 - 0.026 13.5 9.1 0.023 13.6 5.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF973) DUF872 PF05915.7 CAR27824.1 - 0.9 9.4 7.6 0.12 12.2 1.5 2.2 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Herpes_LMP1 PF05297.6 CAR27824.1 - 0.98 8.2 5.8 1.3 7.8 4.0 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF1129 PF06570.6 CAR27824.1 - 1.4 8.2 4.5 1.8 7.7 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) PEMT PF04191.8 CAR27824.1 - 4.6 7.3 11.7 0.21 11.6 2.5 2.4 2 1 0 2 2 2 0 Phospholipid methyltransferase DnaJ_CXXCXGXG PF00684.14 CAR27825.1 - 0.00012 22.0 4.1 0.16 12.0 0.1 2.3 2 0 0 2 2 2 2 DnaJ central domain DUF2082 PF09855.4 CAR27825.1 - 0.023 14.5 0.3 0.043 13.6 0.2 1.5 1 0 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) HypA PF01155.14 CAR27825.1 - 0.13 12.0 0.4 1.5 8.5 0.0 2.1 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family UPF0167 PF03691.9 CAR27825.1 - 0.14 11.5 2.1 0.31 10.4 1.5 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0167) zf-RING_5 PF14634.1 CAR27825.1 - 0.69 9.6 4.6 8.4 6.2 0.1 3.0 3 0 0 3 3 3 0 zinc-RING finger domain GTP_cyclohydroI PF01227.17 CAR27826.1 - 7.3e-75 250.1 0.3 8.6e-75 249.9 0.2 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 CAR27826.1 - 0.00015 21.6 0.0 0.00034 20.4 0.0 1.6 1 0 0 1 1 1 1 QueF-like protein NUC129 PF08157.6 CAR27826.1 - 0.03 14.2 0.1 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 NUC129 domain Pkinase PF00069.20 CAR27827.1 - 2.1e-51 174.5 0.0 3.9e-51 173.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR27827.1 - 8.4e-21 74.2 0.1 1.8e-19 69.8 0.1 2.6 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR27827.1 - 0.00048 19.1 0.1 0.039 12.9 0.0 2.3 2 0 0 2 2 2 2 Kinase-like PhoD PF09423.5 CAR27828.1 - 2.8e-05 22.8 0.1 0.00046 18.8 0.1 2.3 1 1 0 1 1 1 1 PhoD-like phosphatase DEAD PF00270.24 CAR27829.1 - 4e-44 150.0 0.3 3.3e-43 147.1 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR27829.1 - 3.7e-22 77.9 0.0 7.6e-22 76.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CAR27829.1 - 2.5e-20 71.7 0.3 5e-20 70.8 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 CAR27829.1 - 0.00072 19.4 0.2 0.003 17.4 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 CAR27829.1 - 0.0065 15.7 0.0 0.02 14.1 0.0 1.8 1 1 0 1 1 1 1 SecA DEAD-like domain AAA_22 PF13401.1 CAR27829.1 - 0.049 13.7 1.2 0.22 11.6 0.6 2.3 2 1 0 2 2 2 0 AAA domain tRNA-synt_1g PF09334.6 CAR27830.1 - 9.4e-146 485.4 0.3 1.3e-145 484.9 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) MetRS-N PF09635.5 CAR27830.1 - 5.6e-42 142.9 0.6 1e-41 142.1 0.4 1.5 1 0 0 1 1 1 1 MetRS-N binding domain tRNA-synt_1 PF00133.17 CAR27830.1 - 5.7e-10 37.8 0.5 7.3e-05 20.9 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) GST_N PF02798.15 CAR27830.1 - 0.0057 16.8 0.0 0.016 15.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF2424 PF10340.4 CAR27831.1 - 6e-70 235.7 0.0 6.8e-70 235.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 CAR27831.1 - 8.4e-20 71.2 0.0 1.2e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CAR27831.1 - 0.0085 15.8 0.0 0.022 14.5 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family COesterase PF00135.23 CAR27831.1 - 0.068 11.8 0.0 0.39 9.3 0.0 1.9 2 0 0 2 2 2 0 Carboxylesterase family Kdo PF06293.9 CAR27832.1 - 6e-07 28.7 0.0 8.1e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CAR27832.1 - 8e-05 22.4 0.0 0.0026 17.5 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 CAR27832.1 - 0.0035 16.5 0.0 0.0049 16.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain DUF4135 PF13575.1 CAR27832.1 - 0.15 11.0 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Aminotran_4 PF01063.14 CAR27833.1 - 8.8e-22 77.7 0.0 2e-21 76.5 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class IV DUF1344 PF07076.6 CAR27833.1 - 0.18 11.3 0.3 0.46 10.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) Adaptin_N PF01602.15 CAR27834.1 - 1.6e-99 333.6 2.6 1.9e-99 333.4 1.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 CAR27834.1 - 2.9e-09 37.0 0.1 4.9e-06 26.7 0.0 4.1 2 2 2 4 4 4 2 HEAT repeats HEAT PF02985.17 CAR27834.1 - 5.3e-07 29.1 5.7 0.22 11.7 0.0 6.6 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 CAR27834.1 - 0.0012 19.2 0.7 12 6.5 0.1 4.9 2 1 3 5 5 5 1 HEAT-like repeat Cnd1 PF12717.2 CAR27834.1 - 0.0074 16.1 0.2 2.2 8.1 0.0 3.5 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 CAR27834.1 - 0.09 12.1 0.4 15 4.8 0.0 3.4 2 1 1 3 3 3 0 CLASP N terminal HEAT_2 PF13646.1 CAR27835.1 - 3.9e-11 43.0 2.4 0.022 15.0 0.0 7.5 4 3 4 8 8 8 4 HEAT repeats HEAT_EZ PF13513.1 CAR27835.1 - 1.1e-09 38.4 0.1 1.5 9.3 0.0 8.0 9 0 0 9 9 9 3 HEAT-like repeat HEAT PF02985.17 CAR27835.1 - 0.001 18.9 22.6 13 6.1 0.1 11.1 15 0 0 15 15 15 2 HEAT repeat Vac14_Fab1_bd PF12755.2 CAR27835.1 - 0.0018 18.5 0.2 4.2 7.8 0.0 5.4 4 2 2 6 6 6 1 Vacuolar 14 Fab1-binding region Gpi16 PF04113.9 CAR27836.1 - 2.4e-187 623.4 0.0 3.2e-187 622.9 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Elong_Iki1 PF10483.4 CAR27837.1 - 1e-85 287.5 0.7 1.2e-85 287.3 0.5 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 Raptor_N PF14538.1 CAR27838.1 - 6.8e-66 220.8 2.7 8.9e-66 220.4 0.0 2.3 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain HEAT PF02985.17 CAR27838.1 - 2e-08 33.5 3.0 0.0024 17.8 0.0 5.9 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.1 CAR27838.1 - 7.2e-07 29.4 0.0 0.00016 21.8 0.0 3.0 3 0 0 3 3 3 1 HEAT repeats WD40 PF00400.27 CAR27838.1 - 0.0007 19.3 3.9 9.5 6.2 0.0 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat BBS2_Mid PF14783.1 CAR27838.1 - 0.0081 15.9 0.1 0.24 11.1 0.0 2.7 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region HEAT_EZ PF13513.1 CAR27838.1 - 0.24 11.9 0.7 18 5.9 0.0 3.4 3 1 0 3 3 3 0 HEAT-like repeat XPG_N PF00752.12 CAR27839.1 - 1.3e-36 124.8 0.0 3.3e-36 123.5 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 CAR27839.1 - 2e-26 91.8 0.0 8e-26 89.9 0.0 2.2 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 CAR27839.1 - 0.00076 19.6 0.0 0.00076 19.6 0.0 2.9 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold Mito_carr PF00153.22 CAR27841.1 - 2.3e-61 203.5 0.0 1.9e-19 69.1 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein 6PGD PF00393.14 CAR27843.1 - 3.4e-131 436.7 0.0 4.2e-131 436.4 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 CAR27843.1 - 4.3e-50 169.7 0.0 6.3e-50 169.1 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 CAR27843.1 - 0.12 12.4 0.0 0.63 10.1 0.0 2.2 3 0 0 3 3 3 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 CAR27843.1 - 0.12 12.4 0.0 0.45 10.6 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Erv26 PF04148.8 CAR27844.1 - 2.1e-83 278.8 3.8 2.4e-83 278.7 2.7 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 BCCT PF02028.12 CAR27844.1 - 0.054 11.7 2.6 0.072 11.3 1.8 1.3 1 0 0 1 1 1 0 BCCT family transporter Cytochrom_C_asm PF01578.15 CAR27844.1 - 0.32 10.5 4.5 0.099 12.1 0.8 1.8 1 1 1 2 2 2 0 Cytochrome C assembly protein P34-Arc PF04045.9 CAR27845.1 - 1.1e-94 316.3 0.1 1.3e-94 315.9 0.1 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc PAT1 PF09770.4 CAR27846.1 - 6.8e-248 825.0 26.9 8e-248 824.8 18.6 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Spore_III_AF PF09581.5 CAR27846.1 - 8.5 6.1 9.0 1.2 8.9 3.3 1.7 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) PI31_Prot_C PF08577.6 CAR27847.1 - 2.4e-10 40.8 7.1 2.4e-10 40.8 4.9 2.3 1 1 1 2 2 2 1 PI31 proteasome regulator DUF3215 PF11503.3 CAR27848.1 - 1.1e-26 92.2 0.2 1.2e-26 92.1 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3215) LMBR1 PF04791.11 CAR27849.1 - 4.9e-08 32.0 23.5 9.7e-07 27.7 16.3 2.1 1 1 0 1 1 1 1 LMBR1-like membrane protein BCDHK_Adom3 PF10436.4 CAR27850.1 - 6.3e-61 204.6 0.0 1.1e-60 203.8 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CAR27850.1 - 1.4e-15 56.9 0.0 3.5e-15 55.6 0.0 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PQ-loop PF04193.9 CAR27851.1 - 1.1e-25 88.8 11.5 5.2e-13 48.3 2.0 3.0 3 0 0 3 3 3 2 PQ loop repeat Glucosamine_iso PF01182.15 CAR27852.1 - 4.7e-48 163.5 0.0 7.7e-48 162.8 0.0 1.5 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Chorismate_bind PF00425.13 CAR27853.1 - 5.9e-71 238.8 0.0 8.8e-71 238.2 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 CAR27853.1 - 1e-29 103.4 0.0 1.5e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 CAR27853.1 - 1.5e-13 50.9 0.0 4.3e-13 49.4 0.0 1.8 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 CAR27853.1 - 6.6e-06 25.7 0.0 1.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 ubiquitin PF00240.18 CAR27854.1 - 6.4e-08 31.8 0.2 7.7e-08 31.6 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CAR27854.1 - 0.00015 21.3 0.3 0.00017 21.2 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CC2D2AN-C2 PF15625.1 CAR27854.1 - 0.097 12.1 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 CC2D2A N-terminal C2 domain Metallophos PF00149.23 CAR27855.1 - 2.1e-38 131.7 2.3 2.1e-38 131.7 1.6 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Pkinase PF00069.20 CAR27856.1 - 1.5e-61 207.8 0.0 3.8e-61 206.4 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR27856.1 - 3.1e-34 118.2 0.1 5.7e-26 91.1 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CAR27856.1 - 5e-06 25.6 1.3 0.00015 20.8 0.0 3.2 4 0 0 4 4 4 1 Kinase-like APH PF01636.18 CAR27856.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.27 CAR27857.1 - 2.9e-89 290.0 28.5 8.9e-16 57.0 0.1 8.4 8 0 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 CAR27857.1 - 1.2e-09 38.1 0.3 0.00011 21.9 0.0 3.5 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CAR27857.1 - 2.8e-08 32.3 5.5 0.059 11.5 0.0 4.9 2 1 2 5 5 5 3 Nucleoporin Nup120/160 NLE PF08154.7 CAR27857.1 - 3.2e-06 27.0 0.0 5.6e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nucleoporin_N PF08801.6 CAR27857.1 - 0.0001 21.2 0.6 0.08 11.6 0.2 3.5 2 1 0 2 2 2 2 Nup133 N terminal like Gmad1 PF10647.4 CAR27857.1 - 0.0009 18.7 0.9 0.025 13.9 0.0 2.5 2 1 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain Nbas_N PF15492.1 CAR27857.1 - 0.0012 17.9 1.1 0.61 9.1 0.1 3.1 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 CAR27857.1 - 0.0036 15.6 0.0 0.076 11.3 0.0 2.7 3 1 0 3 3 3 1 Cytochrome D1 heme domain PD40 PF07676.7 CAR27857.1 - 0.0056 16.3 0.0 2.6 7.7 0.0 3.0 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Apc4_WD40 PF12894.2 CAR27857.1 - 0.04 13.4 0.0 0.18 11.3 0.0 2.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.2 CAR27857.1 - 3.6 7.2 8.6 12 5.5 0.1 3.8 3 2 2 5 5 5 0 Transcription factor IIIC subunit delta N-term Img2 PF05046.9 CAR27858.1 - 3.2e-23 81.7 0.3 4.6e-23 81.2 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Glyco_transf_22 PF03901.12 CAR27859.1 - 2.1e-26 92.9 14.9 2.9e-26 92.4 10.3 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family GRAM PF02893.15 CAR27859.1 - 0.089 12.3 0.1 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 GRAM domain Ribophorin_II PF05817.9 CAR27859.1 - 8.8 4.3 6.7 13 3.7 4.7 1.2 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II cobW PF02492.14 CAR27860.1 - 4.8e-43 146.6 0.2 7.5e-43 146.0 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 CAR27860.1 - 3.4e-07 29.8 0.0 5.8e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_18 PF13238.1 CAR27860.1 - 5.7e-05 23.4 1.6 0.00015 22.0 0.2 2.5 2 1 1 3 3 3 1 AAA domain GTP_EFTU PF00009.22 CAR27860.1 - 0.0021 17.5 0.8 0.031 13.7 0.5 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CAR27860.1 - 0.0022 17.9 0.0 0.005 16.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 CAR27860.1 - 0.0023 17.9 0.0 0.0035 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain MobB PF03205.9 CAR27860.1 - 0.0029 17.3 0.0 0.0064 16.2 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 CAR27860.1 - 0.0037 18.0 0.4 0.013 16.2 0.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CAR27860.1 - 0.0057 16.5 0.1 0.025 14.4 0.0 2.2 3 0 0 3 3 1 1 AAA domain Arch_ATPase PF01637.13 CAR27860.1 - 0.011 15.4 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_33 PF13671.1 CAR27860.1 - 0.013 15.3 0.0 0.03 14.1 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_5 PF07728.9 CAR27860.1 - 0.018 14.7 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 CAR27860.1 - 0.023 14.2 0.6 0.053 13.0 0.2 1.7 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 CAR27860.1 - 0.03 14.6 0.8 0.73 10.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 CAR27860.1 - 0.031 13.9 0.0 0.063 12.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.1 CAR27860.1 - 0.045 13.9 0.0 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 CAR27860.1 - 0.046 13.4 0.2 0.098 12.3 0.1 1.5 1 0 0 1 1 1 0 NTPase Zeta_toxin PF06414.7 CAR27860.1 - 0.05 12.6 0.0 0.089 11.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 CAR27860.1 - 0.068 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 CAR27860.1 - 0.081 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ArgK PF03308.11 CAR27860.1 - 0.09 11.5 0.4 0.22 10.2 0.0 1.8 2 0 0 2 2 2 0 ArgK protein SRP54 PF00448.17 CAR27860.1 - 0.17 11.2 1.1 0.64 9.4 0.0 2.3 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Pro_isomerase PF00160.16 CAR27861.1 - 8.1e-29 100.8 0.1 1.3e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Zn_clus PF00172.13 CAR27862.1 - 4.1e-06 26.6 3.9 8.8e-06 25.5 2.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lipase_3 PF01764.20 CAR27863.1 - 2.6e-09 36.8 0.0 5.1e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 CAR27863.1 - 0.006 16.3 0.0 0.021 14.5 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family UPF0227 PF05728.7 CAR27863.1 - 0.096 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_6 PF12697.2 CAR27863.1 - 0.098 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Phos_pyr_kin PF08543.7 CAR27864.1 - 9.5e-15 54.4 0.0 1.3e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 CAR27864.1 - 3e-09 36.4 0.0 7e-07 28.6 0.0 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Borrelia_lipo_1 PF05714.6 CAR27864.1 - 0.057 12.5 0.1 0.1 11.7 0.1 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein Cytokin_check_N PF10407.4 CAR27864.1 - 0.076 12.6 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Cdc14 phosphatase binding protein N-terminus Carb_kinase PF01256.12 CAR27864.1 - 0.079 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate kinase WD40 PF00400.27 CAR27865.1 - 0.00021 21.0 0.0 0.015 15.1 0.2 3.8 5 0 0 5 5 5 1 WD domain, G-beta repeat DUF2963 PF11178.3 CAR27865.1 - 0.0065 15.8 0.7 0.014 14.7 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2963) zf-C3HC4 PF00097.20 CAR27866.1 - 9e-10 38.0 11.9 9e-10 38.0 8.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAR27866.1 - 1.6e-08 34.4 12.4 1.6e-08 34.4 8.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CAR27866.1 - 9.1e-08 31.8 14.3 5.4e-07 29.3 7.8 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 CAR27866.1 - 3.2e-07 29.8 11.7 8e-07 28.6 5.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SAP PF02037.22 CAR27866.1 - 5e-07 29.0 0.0 1.1e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 SAP domain zf-RING_5 PF14634.1 CAR27866.1 - 1.2e-06 28.1 14.0 3.1e-06 26.8 6.3 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.1 CAR27866.1 - 1.8e-06 27.6 5.1 1.8e-06 27.6 3.6 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 CAR27866.1 - 3.4e-05 23.6 9.1 3.4e-05 23.6 6.3 2.6 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING U-box PF04564.10 CAR27866.1 - 9.8e-05 22.2 0.6 0.00074 19.4 0.0 2.6 3 0 0 3 3 3 1 U-box domain zf-rbx1 PF12678.2 CAR27866.1 - 0.0011 19.0 7.8 0.0012 18.9 3.0 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger Mob_synth_C PF06463.8 CAR27866.1 - 0.002 17.7 1.0 0.0057 16.3 0.7 1.9 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C FdhE PF04216.7 CAR27866.1 - 0.0039 16.9 1.8 1 8.9 0.0 2.4 1 1 0 2 2 2 2 Protein involved in formate dehydrogenase formation zf-RING_UBOX PF13445.1 CAR27866.1 - 0.0054 16.4 9.3 0.0054 16.4 6.5 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-MIZ PF02891.15 CAR27866.1 - 1.4 8.5 12.7 19 4.8 6.6 2.7 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger RecR PF02132.10 CAR27866.1 - 4.1 6.9 9.5 3.7 7.0 0.1 3.6 3 0 0 3 3 3 0 RecR protein zf-Nse PF11789.3 CAR27866.1 - 4.5 6.8 10.4 4.9 6.7 4.9 2.4 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Fork_head PF00250.13 CAR27867.1 - 2e-36 123.8 0.2 5.1e-36 122.5 0.1 1.7 1 0 0 1 1 1 1 Fork head domain Daxx PF03344.10 CAR27867.1 - 0.0045 15.5 13.3 0.0059 15.1 9.2 1.2 1 0 0 1 1 1 1 Daxx Family Nop14 PF04147.7 CAR27867.1 - 0.033 12.1 21.6 0.045 11.6 15.0 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 CAR27867.1 - 0.058 12.6 13.8 0.092 12.0 9.6 1.3 1 0 0 1 1 1 0 SDA1 Pox_Ag35 PF03286.9 CAR27867.1 - 0.088 12.3 6.1 0.14 11.6 4.2 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.9 CAR27867.1 - 0.17 9.9 12.7 0.23 9.4 8.8 1.1 1 0 0 1 1 1 0 CDC45-like protein BTV_NS2 PF04514.7 CAR27867.1 - 0.19 10.5 8.8 0.28 10.0 6.1 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Sigma70_ner PF04546.8 CAR27867.1 - 0.2 11.2 16.6 0.37 10.3 11.5 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region BUD22 PF09073.5 CAR27867.1 - 0.22 10.5 14.0 0.32 9.9 9.7 1.2 1 0 0 1 1 1 0 BUD22 VID27 PF08553.5 CAR27867.1 - 0.3 9.2 11.8 0.39 8.8 8.2 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein DUF2457 PF10446.4 CAR27867.1 - 0.51 9.0 31.8 0.29 9.7 18.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Cwf_Cwc_15 PF04889.7 CAR27867.1 - 0.66 9.6 14.8 1.3 8.7 10.3 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein eIF-3c_N PF05470.7 CAR27867.1 - 0.89 7.5 4.5 1.2 7.1 3.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Tim54 PF11711.3 CAR27867.1 - 1.2 7.6 5.9 1.8 7.0 4.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RRN3 PF05327.6 CAR27867.1 - 2.6 6.0 10.6 3.8 5.4 7.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NOA36 PF06524.7 CAR27867.1 - 3 7.0 14.2 4.7 6.3 9.9 1.3 1 0 0 1 1 1 0 NOA36 protein DUF1510 PF07423.6 CAR27867.1 - 6.7 6.0 13.2 11 5.3 9.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CENP-B_dimeris PF09026.5 CAR27867.1 - 6.9 6.9 29.4 0.75 10.0 16.0 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain TRAP_alpha PF03896.11 CAR27867.1 - 7.4 5.4 13.8 13 4.6 9.6 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit G10 PF01125.12 CAR27868.1 - 7.6e-56 187.6 4.5 8.4e-56 187.5 3.1 1.0 1 0 0 1 1 1 1 G10 protein DNase_II PF03265.10 CAR27868.1 - 0.009 15.0 0.1 0.011 14.7 0.1 1.2 1 0 0 1 1 1 1 Deoxyribonuclease II Ytp1 PF10355.4 CAR27869.1 - 1.3e-107 359.0 7.9 1.8e-107 358.5 5.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 CAR27869.1 - 1.2e-31 108.3 6.9 3.6e-31 106.8 4.8 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) UPF0029 PF01205.14 CAR27870.1 - 1.7e-25 88.8 0.0 2.7e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 CAR27870.1 - 1.2e-08 34.8 0.0 2.6e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 RWD domain DinI PF06183.8 CAR27870.1 - 0.023 14.7 0.0 0.12 12.4 0.0 2.2 3 0 0 3 3 3 0 DinI-like family WD40 PF00400.27 CAR27872.1 - 8.3e-51 168.1 19.9 3.8e-11 42.4 0.1 12.5 13 0 0 13 13 13 8 WD domain, G-beta repeat Utp12 PF04003.7 CAR27872.1 - 7.2e-30 103.1 0.0 1.2e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 CAR27872.1 - 2.1e-06 27.5 2.5 0.039 13.6 0.0 6.0 5 1 2 7 7 7 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 CAR27872.1 - 1.1e-05 24.6 0.3 3.3 6.7 0.0 4.3 3 1 1 4 4 4 3 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 CAR27872.1 - 0.0003 19.0 4.9 1 7.4 0.0 3.7 2 1 1 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 CAR27872.1 - 0.0052 15.1 1.6 0.25 9.5 0.1 3.6 3 1 1 4 4 4 1 Cytochrome D1 heme domain CPSF_A PF03178.10 CAR27872.1 - 0.024 13.7 0.0 1.4 7.9 0.0 3.1 3 0 0 3 3 3 0 CPSF A subunit region PD40 PF07676.7 CAR27872.1 - 0.16 11.6 0.6 25 4.6 0.0 3.3 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Atx10homo_assoc PF09759.4 CAR27873.1 - 2.2e-37 126.8 1.8 3.9e-36 122.8 0.1 2.9 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain FliS PF02561.9 CAR27873.1 - 0.069 12.9 2.4 0.34 10.7 0.0 2.7 2 0 0 2 2 2 0 Flagellar protein FliS Thr_synth_N PF14821.1 CAR27874.1 - 6e-28 96.6 0.0 2e-27 95.0 0.0 2.0 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.20 CAR27874.1 - 1.5e-15 57.2 0.0 2.5e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SWIB PF02201.13 CAR27875.1 - 0.045 13.4 0.1 0.17 11.6 0.0 2.0 3 0 0 3 3 3 0 SWIB/MDM2 domain Ribosomal_L9_N PF01281.14 CAR27876.1 - 0.0011 18.1 0.1 0.0023 17.1 0.1 1.6 1 1 0 1 1 1 1 Ribosomal protein L9, N-terminal domain MCLC PF05934.6 CAR27876.1 - 0.096 10.9 2.8 0.4 8.9 2.0 1.7 1 1 0 1 1 1 0 Mid-1-related chloride channel (MCLC) DUF3987 PF13148.1 CAR27876.1 - 0.1 11.1 2.3 0.13 10.8 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Pex14_N PF04695.8 CAR27876.1 - 0.18 11.8 4.8 0.25 11.4 3.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3353 PF11833.3 CAR27876.1 - 0.23 10.9 1.5 0.32 10.4 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) DUF1682 PF07946.9 CAR27877.1 - 5.5e-71 239.0 6.8 6.6e-71 238.7 4.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Ank_5 PF13857.1 CAR27878.1 - 3e-19 68.6 0.0 6.3e-14 51.6 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 CAR27878.1 - 9.1e-14 51.5 0.0 4.3e-11 42.9 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CAR27878.1 - 6.3e-13 48.8 0.1 1.3e-06 28.7 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 CAR27878.1 - 2.9e-11 42.5 0.7 4.2e-06 26.2 0.0 4.1 4 1 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 CAR27878.1 - 3.9e-10 38.9 0.1 7.1e-05 22.6 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Peptidase_M76 PF09768.4 CAR27879.1 - 1.4e-76 255.7 0.7 1.7e-76 255.4 0.5 1.1 1 0 0 1 1 1 1 Peptidase M76 family Baculo_p74 PF04583.7 CAR27879.1 - 0.19 10.9 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Baculoviridae p74 conserved region SprT-like PF10263.4 CAR27879.1 - 0.74 9.4 7.0 0.21 11.2 0.3 2.3 1 1 0 2 2 2 0 SprT-like family MBOAT PF03062.14 CAR27880.1 - 1.7e-57 195.0 42.9 1.8e-56 191.6 29.7 2.0 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 CAR27880.1 - 0.00039 20.4 4.4 0.00039 20.4 3.0 1.9 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family WBS_methylT PF12589.3 CAR27881.1 - 4.1e-18 65.6 6.7 9.5e-18 64.4 4.6 1.7 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 CAR27881.1 - 2.4e-12 47.1 0.1 7.6e-12 45.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAR27881.1 - 6.3e-07 29.6 0.0 1.5e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAR27881.1 - 6.4e-07 29.2 0.0 1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAR27881.1 - 1.3e-05 25.5 0.1 6.4e-05 23.3 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAR27881.1 - 3.5e-05 23.4 0.0 7.7e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CAR27881.1 - 4.1e-05 22.7 0.1 0.00017 20.7 0.0 1.9 2 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 CAR27881.1 - 0.00013 22.4 0.0 0.0004 20.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 CAR27881.1 - 0.00023 20.5 0.0 0.00039 19.8 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.14 CAR27881.1 - 0.00043 19.8 0.0 0.0017 17.9 0.0 1.9 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 CAR27881.1 - 0.0079 16.2 0.0 0.019 15.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CAR27881.1 - 0.014 14.5 0.5 0.045 12.8 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 CAR27881.1 - 0.085 12.5 0.1 0.49 10.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Ribosomal_L19 PF01245.15 CAR27882.1 - 2.2e-12 46.7 0.1 3.5e-12 46.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 DUF4548 PF15081.1 CAR27882.1 - 0.011 15.2 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4548) NPCBM_assoc PF10633.4 CAR27882.1 - 0.059 13.4 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase HIG_1_N PF04588.8 CAR27883.1 - 0.00012 21.7 2.7 0.00037 20.1 1.9 2.0 1 1 0 1 1 1 1 Hypoxia induced protein conserved region Peptidase_S8 PF00082.17 CAR27884.1 - 9.6e-45 152.8 0.5 1.3e-44 152.4 0.3 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 CAR27884.1 - 8.4e-05 23.0 0.0 0.00016 22.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 KH_dom-like PF14714.1 CAR27884.1 - 0.0098 15.8 0.2 0.25 11.3 0.1 2.4 2 0 0 2 2 2 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal Tim17 PF02466.14 CAR27885.1 - 8.3e-28 96.9 3.0 1.1e-27 96.6 2.1 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.4 CAR27885.1 - 0.057 13.5 5.8 2.7 8.1 0.0 2.4 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide DUF3415 PF11895.3 CAR27885.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3415) DUF4611 PF15387.1 CAR27887.1 - 0.18 11.9 3.7 0.31 11.2 2.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) ACC_central PF08326.7 CAR27888.1 - 6.7e-261 867.4 0.0 9.2e-261 866.9 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 CAR27888.1 - 1.6e-175 584.2 0.0 2.1e-175 583.8 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 CAR27888.1 - 2.5e-50 170.6 0.1 6.5e-50 169.3 0.0 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CAR27888.1 - 3.7e-25 88.1 0.1 1e-24 86.7 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CAR27888.1 - 1.2e-20 73.5 0.0 8.2e-20 70.7 0.0 2.4 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 CAR27888.1 - 4.8e-17 61.3 0.2 1.2e-16 60.1 0.2 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 CAR27888.1 - 2e-10 40.6 0.0 8.3e-10 38.7 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CAR27888.1 - 1.1e-07 30.9 0.0 0.00045 19.0 0.0 3.1 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 CAR27888.1 - 0.00061 19.2 0.0 0.0014 18.0 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 CAR27888.1 - 0.0076 16.1 0.0 0.047 13.5 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.17 CAR27888.1 - 0.027 13.8 0.0 0.072 12.4 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain Dus PF01207.12 CAR27889.1 - 1.7e-52 178.1 0.0 5.9e-52 176.4 0.0 1.8 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) DUF1708 PF08101.6 CAR27890.1 - 1.5e-42 145.9 0.9 2.2e-42 145.3 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) SPX PF03105.14 CAR27892.1 - 1.4e-49 169.3 2.2 2.2e-49 168.6 1.5 1.3 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 CAR27892.1 - 2e-20 73.1 43.3 2.8e-20 72.6 30.0 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 CAR27892.1 - 3.6e-15 55.3 44.2 4.1e-12 45.3 12.6 2.1 1 1 1 2 2 2 2 Citrate transporter DUF373 PF04123.8 CAR27892.1 - 7.8 5.4 15.3 0.72 8.8 4.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF373) PRK PF00485.13 CAR27893.1 - 2.9e-62 209.6 0.0 4.1e-62 209.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 CAR27893.1 - 1.3e-30 106.2 0.2 2.5e-30 105.2 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 CAR27893.1 - 7e-11 43.0 0.0 1.6e-10 41.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CAR27893.1 - 7.7e-07 29.4 0.0 2.9e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CAR27893.1 - 0.00015 21.6 0.0 0.00079 19.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CAR27893.1 - 0.0015 17.6 0.0 0.0028 16.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin CPT PF07931.7 CAR27893.1 - 0.0089 15.6 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein KAP_NTPase PF07693.9 CAR27893.1 - 0.048 12.6 0.0 0.067 12.1 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain AAA PF00004.24 CAR27893.1 - 0.05 13.7 0.0 0.32 11.1 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CAR27893.1 - 0.058 13.5 0.0 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 CAR27893.1 - 0.08 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 CAR27893.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain OB_NTP_bind PF07717.11 CAR27894.1 - 1.9e-17 63.0 0.0 4.3e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CAR27894.1 - 4.3e-17 61.9 0.5 1.1e-16 60.6 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CAR27894.1 - 7.6e-11 41.7 0.0 1.8e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAR27894.1 - 5.2e-07 29.3 0.2 1.1e-06 28.2 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CAR27894.1 - 2.2e-05 24.6 1.0 4.6e-05 23.5 0.1 2.0 2 0 0 2 2 1 1 AAA domain T2SE PF00437.15 CAR27894.1 - 0.0003 19.7 0.0 0.00061 18.7 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 CAR27894.1 - 0.0075 16.1 1.5 0.87 9.3 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit ABC_tran PF00005.22 CAR27894.1 - 0.015 15.6 1.7 0.064 13.5 0.0 2.9 3 1 0 3 3 3 0 ABC transporter Flavi_DEAD PF07652.9 CAR27894.1 - 0.019 14.7 0.1 0.038 13.7 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_19 PF13245.1 CAR27894.1 - 0.025 14.3 0.1 0.069 12.9 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 CAR27894.1 - 0.027 14.0 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 CAR27894.1 - 0.029 13.5 0.2 0.08 12.1 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_14 PF13173.1 CAR27894.1 - 0.035 13.9 0.6 1.1 9.1 0.4 2.7 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 CAR27894.1 - 0.096 12.3 0.4 1.8 8.2 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Glyoxalase PF00903.20 CAR27895.1 - 3.8e-35 120.6 0.1 1.3e-18 67.2 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 CAR27895.1 - 5.4e-30 104.1 0.0 1e-13 51.8 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 CAR27895.1 - 3.1e-13 49.6 0.0 6.4e-06 26.1 0.0 3.5 1 1 3 4 4 4 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 CAR27895.1 - 0.00031 20.6 0.0 0.11 12.3 0.0 3.2 2 2 0 2 2 2 2 Glyoxalase-like domain AA_permease PF00324.16 CAR27896.1 - 6.6e-81 272.0 39.3 8.4e-81 271.7 27.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CAR27896.1 - 1.4e-24 86.4 43.8 2.3e-24 85.7 30.4 1.3 1 0 0 1 1 1 1 Amino acid permease Peptidase_M19 PF01244.16 CAR27897.1 - 6.9e-102 340.6 0.0 8e-102 340.4 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Autotransporter PF03797.14 CAR27897.1 - 0.066 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Autotransporter beta-domain PFK PF00365.15 CAR27898.1 - 2.3e-167 555.0 2.6 2.1e-123 410.8 1.5 2.1 2 0 0 2 2 2 2 Phosphofructokinase PurS PF02700.9 CAR27898.1 - 0.11 12.4 0.1 0.37 10.7 0.0 2.0 2 0 0 2 2 2 0 Phosphoribosylformylglycinamidine (FGAM) synthase Inp1 PF12634.2 CAR27899.1 - 8.2e-35 119.6 2.7 1.7e-34 118.5 0.1 2.5 2 2 1 3 3 3 1 Inheritance of peroxisomes protein 1 bZIP_1 PF00170.16 CAR27900.1 - 1.2e-14 53.9 14.5 2e-14 53.2 10.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CAR27900.1 - 1.6e-11 43.8 15.8 2.8e-11 43.0 11.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper DivIC PF04977.10 CAR27900.1 - 0.023 14.1 3.7 0.041 13.3 2.6 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF4355 PF14265.1 CAR27900.1 - 0.068 13.1 7.1 0.1 12.5 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) DUF972 PF06156.8 CAR27900.1 - 0.3 11.4 2.8 0.51 10.7 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Mnd1 PF03962.10 CAR27900.1 - 0.47 10.0 3.7 0.84 9.2 2.1 1.6 2 0 0 2 2 2 0 Mnd1 family XhlA PF10779.4 CAR27900.1 - 0.83 9.6 2.7 1.3 8.9 1.8 1.3 1 0 0 1 1 1 0 Haemolysin XhlA Gti1_Pac2 PF09729.4 CAR27901.1 - 1e-49 168.6 0.4 5.4e-49 166.3 0.0 2.0 2 0 0 2 2 2 1 Gti1/Pac2 family Mito_carr PF00153.22 CAR27902.1 - 1.3e-75 249.1 0.9 9.8e-27 92.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Thioredoxin PF00085.15 CAR27903.1 - 2.8e-21 75.1 0.1 2.1e-16 59.4 0.0 4.2 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 CAR27903.1 - 1.7e-08 34.4 0.6 0.00045 20.0 0.0 3.4 2 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CAR27903.1 - 3.3e-05 23.9 0.9 0.00046 20.2 0.0 3.2 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_4 PF13462.1 CAR27903.1 - 6.8e-05 22.9 0.7 0.0014 18.7 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin zf-ribbon_3 PF13248.1 CAR27903.1 - 0.93 8.7 3.3 14 5.0 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain SNARE PF05739.14 CAR27904.1 - 4.4e-09 35.8 1.7 6.7e-09 35.3 1.2 1.3 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 CAR27904.1 - 0.00089 18.7 0.9 0.0011 18.4 0.6 1.3 1 1 0 1 1 1 1 Membrane fusion protein Use1 Synaptobrevin PF00957.16 CAR27904.1 - 2.4 7.8 5.2 5.1 6.7 3.6 1.6 1 1 0 1 1 1 0 Synaptobrevin ParA PF10609.4 CAR27905.1 - 1.1e-37 127.8 0.0 3.4e-37 126.2 0.0 1.8 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 CAR27905.1 - 5e-18 65.1 0.0 7.7e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 CAR27905.1 - 1.4e-06 27.6 0.0 8e-06 25.1 0.0 1.9 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 CAR27905.1 - 1.1e-05 24.6 0.0 0.00011 21.4 0.1 2.2 3 0 0 3 3 3 1 Anion-transporting ATPase AAA_31 PF13614.1 CAR27905.1 - 0.00056 19.8 0.0 0.0027 17.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 CAR27905.1 - 0.0098 14.6 0.1 0.017 13.9 0.0 1.3 1 0 0 1 1 1 1 ArgK protein zf-C4_ClpX PF06689.8 CAR27905.1 - 0.012 15.1 2.1 0.023 14.1 1.5 1.4 1 0 0 1 1 1 0 ClpX C4-type zinc finger YhjQ PF06564.7 CAR27905.1 - 0.015 14.6 0.1 0.029 13.7 0.0 1.6 1 1 0 1 1 1 0 YhjQ protein AAA_19 PF13245.1 CAR27905.1 - 0.018 14.8 0.0 5.6 6.7 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain AAA_25 PF13481.1 CAR27905.1 - 0.029 13.7 0.1 0.049 13.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 CAR27905.1 - 0.054 12.9 0.0 0.49 9.8 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein Fer4_NifH PF00142.13 CAR27905.1 - 0.11 11.6 0.0 0.37 9.9 0.0 1.8 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_30 PF13604.1 CAR27905.1 - 0.13 11.8 0.0 2.3 7.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_26 PF13500.1 CAR27905.1 - 0.17 11.5 0.1 1.6 8.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain Pap_E4 PF02711.9 CAR27906.1 - 0.52 11.1 5.0 0.99 10.2 3.5 1.5 1 0 0 1 1 1 0 E4 protein Prefoldin_2 PF01920.15 CAR27907.1 - 1.1e-19 70.1 6.8 1.2e-19 70.0 4.7 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF2935 PF11155.3 CAR27907.1 - 0.0071 16.4 1.1 0.0092 16.0 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2935) Ribosomal_L25p PF01386.14 CAR27907.1 - 0.061 13.4 0.6 0.11 12.5 0.1 1.7 2 0 0 2 2 2 0 Ribosomal L25p family UBN2 PF14223.1 CAR27907.1 - 0.09 12.5 2.1 0.19 11.4 0.3 1.9 1 1 1 2 2 2 0 gag-polypeptide of LTR copia-type DUF342 PF03961.8 CAR27907.1 - 0.12 10.7 5.5 0.15 10.4 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF904 PF06005.7 CAR27907.1 - 0.18 12.0 6.5 1.7 8.9 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF3010 PF11215.3 CAR27907.1 - 0.2 11.5 3.6 7 6.5 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3010) BLOC1_2 PF10046.4 CAR27907.1 - 0.36 10.9 9.0 0.66 10.1 1.3 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6 PF04111.7 CAR27907.1 - 0.65 8.9 5.6 0.3 10.1 2.2 1.5 1 1 1 2 2 2 0 Autophagy protein Apg6 DivIC PF04977.10 CAR27907.1 - 1.5 8.3 4.6 3.6 7.1 0.4 2.2 1 1 1 2 2 2 0 Septum formation initiator DUF972 PF06156.8 CAR27907.1 - 2.2 8.6 4.8 5.4 7.3 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DDOST_48kD PF03345.9 CAR27908.1 - 2.2e-127 425.1 1.4 2.7e-127 424.8 1.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF2410 PF10307.4 CAR27908.1 - 0.05 12.9 0.1 0.093 12.0 0.0 1.4 1 0 0 1 1 1 0 Hypothetical protein (DUF2410) L6_membrane PF05805.7 CAR27909.1 - 0.13 11.7 6.0 0.17 11.4 4.2 1.3 1 1 0 1 1 1 0 L6 membrane protein Syja_N PF02383.13 CAR27910.1 - 4.2e-64 216.3 0.4 8e-64 215.4 0.3 1.4 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 CAR27910.1 - 1.9e-19 70.5 0.0 3.1e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family BTB PF00651.26 CAR27911.1 - 6.3e-17 61.5 0.8 1.6e-14 53.8 0.3 2.6 2 0 0 2 2 2 2 BTB/POZ domain Ank_2 PF12796.2 CAR27911.1 - 3e-09 37.0 0.0 1.4e-08 34.9 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 CAR27911.1 - 4.7e-09 35.6 0.9 1.3e-06 27.8 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CAR27911.1 - 4.3e-07 30.2 0.1 2.2e-06 28.0 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CAR27911.1 - 1.5e-06 27.8 0.1 0.0067 16.5 0.0 3.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 CAR27911.1 - 0.00031 20.8 0.0 0.0015 18.7 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF3342 PF11822.3 CAR27911.1 - 0.033 13.3 0.5 0.058 12.5 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) RRM_1 PF00076.17 CAR27913.1 - 5.4e-20 70.8 0.0 9.4e-20 70.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR27913.1 - 8.8e-18 64.0 0.0 2e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR27913.1 - 1.2e-10 41.0 0.0 2.6e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CAR27913.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Nop16 PF09420.5 CAR27914.1 - 2e-59 200.3 16.9 2.6e-59 199.9 11.7 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Daxx PF03344.10 CAR27914.1 - 0.092 11.2 20.8 0.11 10.9 14.4 1.2 1 0 0 1 1 1 0 Daxx Family PMI_typeI PF01238.16 CAR27915.1 - 1.9e-151 504.2 0.0 2.2e-151 504.0 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.14 CAR27915.1 - 3.3e-05 23.5 0.0 0.0021 17.7 0.0 2.6 3 0 0 3 3 3 1 AraC-like ligand binding domain Cupin_2 PF07883.6 CAR27915.1 - 0.0011 18.3 0.0 0.72 9.4 0.0 2.3 2 0 0 2 2 2 2 Cupin domain HIM1 PF08732.5 CAR27916.1 - 2.3e-11 42.7 0.1 1.8e-08 33.2 0.0 2.5 1 1 2 3 3 3 2 HIM1 NAD_binding_10 PF13460.1 CAR27916.1 - 5.9e-11 42.6 0.0 7.4e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CAR27916.1 - 2.5e-06 26.9 0.0 1.9e-05 24.0 0.0 2.0 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 CAR27916.1 - 0.00012 21.6 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDA1_CD39 PF01150.12 CAR27917.1 - 9.9e-144 479.0 0.0 1.3e-143 478.6 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 CAR27917.1 - 0.006 15.8 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 Ppx/GppA phosphatase family GN3L_Grn1 PF08701.6 CAR27918.1 - 3.7e-25 87.6 14.3 1.2e-24 86.0 9.9 1.9 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 CAR27918.1 - 1.3e-21 76.7 0.1 7.9e-16 58.0 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CAR27918.1 - 6e-07 28.8 0.1 3.2e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 CAR27918.1 - 3.6e-05 23.2 0.0 0.049 13.0 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CAR27918.1 - 8e-05 21.8 0.1 0.00014 21.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CAR27918.1 - 0.00011 22.1 4.7 0.065 13.0 0.1 3.7 2 2 1 3 3 3 2 Dynamin family AIG1 PF04548.11 CAR27918.1 - 0.00018 20.7 0.0 0.00051 19.2 0.0 1.8 2 0 0 2 2 2 1 AIG1 family Miro PF08477.8 CAR27918.1 - 0.002 18.6 0.1 0.067 13.6 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein cobW PF02492.14 CAR27918.1 - 0.0076 15.7 0.1 3.3 7.1 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 CAR27918.1 - 0.0085 14.8 0.0 0.019 13.7 0.0 1.5 1 0 0 1 1 1 1 ArgK protein MobB PF03205.9 CAR27918.1 - 0.057 13.1 0.1 0.34 10.6 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 CAR27918.1 - 0.07 13.4 3.7 0.074 13.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CAR27918.1 - 1.4 9.7 4.6 1.6 9.5 0.0 2.6 2 1 0 2 2 2 0 AAA domain LRR_4 PF12799.2 CAR27919.1 - 8.2e-18 63.6 21.1 3.2e-06 26.6 1.9 5.8 4 2 3 7 7 7 5 Leucine Rich repeats (2 copies) CAP_GLY PF01302.20 CAR27919.1 - 4.6e-17 61.4 0.1 8.4e-17 60.6 0.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_8 PF13855.1 CAR27919.1 - 3.7e-09 36.1 22.2 6.6e-06 25.7 3.3 5.1 4 2 0 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 CAR27919.1 - 1.7e-07 30.2 28.5 1.4 9.1 0.3 9.3 6 2 2 8 8 8 3 Leucine Rich Repeat LRR_7 PF13504.1 CAR27919.1 - 7.8e-06 25.2 22.1 2.4 8.7 0.0 8.7 9 0 0 9 9 9 3 Leucine rich repeat LRR_6 PF13516.1 CAR27919.1 - 0.00045 20.0 22.9 3.1 8.1 0.3 8.4 9 0 0 9 9 9 2 Leucine Rich repeat ubiquitin PF00240.18 CAR27919.1 - 0.094 12.1 0.5 1.6 8.1 0.1 2.8 2 1 0 2 2 2 0 Ubiquitin family PUA PF01472.15 CAR27920.1 - 6.9e-22 76.9 0.0 1e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.5 CAR27920.1 - 0.012 15.3 1.2 0.017 14.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) NCA2 PF08637.5 CAR27922.1 - 3.4e-93 311.6 2.4 3.4e-93 311.6 1.7 1.5 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 SH3_9 PF14604.1 CAR27923.1 - 4e-14 51.9 0.0 6.1e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CAR27923.1 - 7.2e-14 50.9 0.0 1e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CAR27923.1 - 3.4e-11 42.4 0.0 4.9e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF2076 PF09849.4 CAR27923.1 - 0.0097 15.9 3.4 0.012 15.6 2.4 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Pex14_N PF04695.8 CAR27923.1 - 0.32 11.0 2.1 0.44 10.5 1.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.4 CAR27923.1 - 0.35 9.0 10.9 0.38 8.9 7.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 CAR27923.1 - 6.1 6.1 9.6 7.2 5.8 6.7 1.1 1 0 0 1 1 1 0 Vta1 like Tmemb_170 PF10190.4 CAR27924.1 - 0.058 13.4 3.8 0.068 13.2 2.6 1.1 1 0 0 1 1 1 0 Putative transmembrane protein 170 Gly-zipper_YMGG PF13441.1 CAR27924.1 - 0.1 12.0 1.0 0.17 11.4 0.7 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper DUF1129 PF06570.6 CAR27924.1 - 0.22 10.7 1.1 0.26 10.5 0.7 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Romo1 PF10247.4 CAR27924.1 - 1.3 9.2 4.8 12 6.1 2.0 2.2 1 1 1 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Proteasome PF00227.21 CAR27925.1 - 2e-57 193.5 0.8 2.5e-57 193.2 0.5 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CAR27925.1 - 1.7e-13 49.6 4.1 4.1e-13 48.3 0.2 3.0 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature Lipocalin_6 PF13944.1 CAR27925.1 - 0.012 15.7 1.4 0.7 10.0 0.4 2.1 2 0 0 2 2 2 0 Lipocalin-like domain WW PF00397.21 CAR27926.1 - 2.6e-17 62.3 6.4 3.2e-09 36.4 1.4 2.5 2 0 0 2 2 2 2 WW domain FF PF01846.14 CAR27926.1 - 7.1e-06 25.8 1.8 7.1e-06 25.8 1.3 3.6 5 0 0 5 5 5 1 FF domain Pet20 PF08692.5 CAR27928.1 - 3.9e-44 149.9 0.0 5.3e-44 149.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial protein Pet20 Ribonuc_L-PSP PF01042.16 CAR27929.1 - 2.8e-23 81.9 0.0 3.6e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP UQ_con PF00179.21 CAR27930.1 - 2.3e-39 134.0 0.0 2.5e-39 133.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 CAR27930.1 - 0.001 18.7 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 UEV domain UFC1 PF08694.6 CAR27930.1 - 0.001 18.5 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 Prok-E2_B PF14461.1 CAR27930.1 - 0.0013 18.4 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CAR27930.1 - 0.014 15.3 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain CD36 PF01130.16 CAR27930.1 - 0.095 10.9 0.0 0.11 10.7 0.0 1.0 1 0 0 1 1 1 0 CD36 family Band_7 PF01145.20 CAR27931.1 - 5e-24 85.1 1.9 5.8e-24 84.9 0.7 1.5 1 1 1 2 2 2 1 SPFH domain / Band 7 family OPT PF03169.10 CAR27932.1 - 2.8e-156 521.5 48.1 3.3e-156 521.3 33.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MARVEL PF01284.18 CAR27934.1 - 3.2e-28 98.3 15.7 4.6e-28 97.8 10.9 1.2 1 0 0 1 1 1 1 Membrane-associating domain BAR_2 PF10455.4 CAR27936.1 - 5.1e-93 311.1 13.1 7e-93 310.6 9.1 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF3813 PF12758.2 CAR27936.1 - 0.026 14.6 2.1 0.061 13.4 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3813) DAP_B PF07930.7 CAR27936.1 - 0.25 11.0 2.4 30 4.4 0.0 3.5 2 1 1 3 3 3 0 D-aminopeptidase, domain B Herpes_UL6 PF01763.11 CAR27936.1 - 0.32 9.1 7.3 0.5 8.4 5.1 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like Peptidase_S30 PF01577.11 CAR27936.1 - 0.45 9.8 8.2 0.8 9.0 5.7 1.4 1 0 0 1 1 1 0 Potyvirus P1 protease SYF2 PF08231.7 CAR27937.1 - 1e-10 41.9 16.9 1e-10 41.9 11.7 1.6 2 0 0 2 2 2 1 SYF2 splicing factor Utp8 PF10395.4 CAR27938.1 - 4.2e-209 696.1 12.7 4.7e-209 696.0 8.8 1.0 1 0 0 1 1 1 1 Utp8 family DUF2305 PF10230.4 CAR27939.1 - 2e-65 220.8 0.2 2.3e-65 220.6 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 CAR27939.1 - 5.9e-11 42.6 0.0 7.6e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CAR27939.1 - 4.4e-05 23.2 0.0 6e-05 22.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 CAR27939.1 - 0.0009 18.8 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 CAR27939.1 - 0.0035 17.6 0.0 0.0042 17.3 0.0 1.3 1 1 0 1 1 1 1 Thioesterase domain DUF1057 PF06342.7 CAR27939.1 - 0.0078 15.0 0.3 0.069 11.9 0.2 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Peptidase_S9 PF00326.16 CAR27939.1 - 0.0083 15.3 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Ser_hydrolase PF06821.8 CAR27939.1 - 0.015 14.9 0.3 1.7 8.2 0.0 2.3 1 1 1 2 2 2 0 Serine hydrolase DUF3089 PF11288.3 CAR27939.1 - 0.021 13.9 0.1 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) PGAP1 PF07819.8 CAR27939.1 - 0.038 13.5 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 CAR27939.1 - 0.07 12.7 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) NRDE PF05742.7 CAR27940.1 - 6e-38 130.7 0.0 7.6e-38 130.3 0.0 1.0 1 0 0 1 1 1 1 NRDE protein CENP-O PF09496.5 CAR27941.1 - 7.4e-20 70.9 2.2 1.1e-19 70.4 0.2 2.1 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component DUF1192 PF06698.6 CAR27941.1 - 0.013 15.2 0.5 0.032 14.0 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Osmo_CC PF08946.5 CAR27941.1 - 0.015 15.3 1.4 0.015 15.3 1.0 2.5 3 0 0 3 3 3 0 Osmosensory transporter coiled coil FlaC_arch PF05377.6 CAR27941.1 - 0.026 14.4 0.9 0.99 9.3 0.5 2.9 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) GIT1_C PF12205.3 CAR27941.1 - 0.06 13.1 0.3 0.11 12.3 0.2 1.4 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term DivIC PF04977.10 CAR27941.1 - 0.14 11.6 1.3 0.45 10.0 0.9 1.9 1 0 0 1 1 1 0 Septum formation initiator Scs3p PF10261.4 CAR27942.1 - 3.4e-41 140.8 10.9 8.2e-41 139.6 7.5 1.6 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.16 CAR27942.1 - 0.026 14.1 3.7 0.063 12.9 2.5 1.7 1 1 0 1 1 1 0 PAP2 superfamily Orai-1 PF07856.7 CAR27942.1 - 0.18 11.3 1.4 0.31 10.5 1.0 1.3 1 0 0 1 1 1 0 Mediator of CRAC channel activity Prenyltrans PF00432.16 CAR27943.1 - 2.3e-25 87.8 4.0 1.7e-11 43.5 0.4 4.6 5 0 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 CAR27943.1 - 5.3e-23 81.1 0.0 1e-11 44.7 0.1 5.5 3 3 2 5 5 5 3 Prenyltransferase-like Prenyltrans_2 PF13249.1 CAR27943.1 - 3e-21 75.9 0.0 3e-15 56.5 0.0 4.6 2 2 2 4 4 4 3 Prenyltransferase-like A2M_comp PF07678.9 CAR27943.1 - 0.0011 18.2 0.1 0.0072 15.5 0.0 2.3 2 1 0 2 2 2 1 A-macroglobulin complement component Pec_lyase PF09492.5 CAR27943.1 - 0.056 12.6 0.1 7.9 5.5 0.0 3.3 2 1 2 4 4 4 0 Pectic acid lyase Ubiq-assoc PF09145.5 CAR27944.1 - 1.3e-16 60.1 1.4 3.1e-16 58.9 1.0 1.7 1 0 0 1 1 1 1 Ubiquitin-associated TPR_11 PF13414.1 CAR27944.1 - 2e-09 36.9 0.4 2e-07 30.5 0.0 2.8 3 0 0 3 3 3 1 TPR repeat TPR_12 PF13424.1 CAR27944.1 - 4.3e-07 29.7 0.3 6.6e-06 25.9 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 CAR27944.1 - 2.5e-06 26.9 1.0 1.5 8.9 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 CAR27944.1 - 2.4e-05 24.5 0.0 2.7 8.8 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat DnaJ PF00226.26 CAR27944.1 - 0.00094 18.8 0.3 0.0045 16.7 0.0 2.2 2 0 0 2 2 2 1 DnaJ domain TPR_19 PF14559.1 CAR27944.1 - 0.003 17.8 0.6 0.018 15.3 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3856 PF12968.2 CAR27944.1 - 0.0072 16.1 0.0 0.026 14.3 0.0 1.8 1 1 0 1 1 1 1 Domain of Unknown Function (DUF3856) TPR_1 PF00515.23 CAR27944.1 - 0.0073 15.8 3.9 14 5.4 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 CAR27944.1 - 0.018 15.7 0.0 0.5 11.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Nop10p PF04135.7 CAR27945.1 - 6.2e-21 73.8 0.2 7.8e-21 73.5 0.1 1.2 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family DASH_Dad4 PF08650.5 CAR27946.1 - 1.5e-37 127.3 8.3 1.6e-37 127.1 5.7 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 NPV_P10 PF05531.7 CAR27946.1 - 0.00089 19.4 0.8 0.0011 19.2 0.6 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein DUF3251 PF11622.3 CAR27946.1 - 0.0098 15.3 0.6 0.011 15.1 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3251) DASH_Dad3 PF08656.5 CAR27946.1 - 0.016 14.8 0.5 0.02 14.5 0.3 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad3 Nsp1_C PF05064.8 CAR27946.1 - 0.035 13.7 0.4 0.04 13.5 0.3 1.1 1 0 0 1 1 1 0 Nsp1-like C-terminal region TMF_TATA_bd PF12325.3 CAR27946.1 - 0.064 12.9 0.3 0.078 12.7 0.2 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding FAM117 PF15388.1 CAR27946.1 - 0.1 11.7 0.9 0.11 11.7 0.6 1.1 1 0 0 1 1 1 0 Protein Family FAM117 DUF4206 PF13901.1 CAR27946.1 - 0.1 12.1 0.3 0.11 12.0 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) Occludin_ELL PF07303.8 CAR27946.1 - 0.13 12.9 0.1 0.14 12.8 0.1 1.1 1 0 0 1 1 1 0 Occludin homology domain Pkinase PF00069.20 CAR27947.1 - 8.5e-50 169.3 0.3 2.7e-49 167.6 0.2 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR27947.1 - 8.2e-21 74.2 0.1 3.6e-20 72.1 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR27947.1 - 5.7e-05 22.2 0.0 0.0016 17.4 0.0 2.3 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 CAR27947.1 - 0.032 13.5 0.1 0.063 12.6 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Peptidase_C13 PF01650.13 CAR27948.1 - 1.9e-46 158.4 1.0 2.7e-46 157.9 0.7 1.2 1 0 0 1 1 1 1 Peptidase C13 family Thioredoxin_7 PF13899.1 CAR27949.1 - 1.4e-20 73.0 0.1 2.7e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.15 CAR27949.1 - 3.3e-18 65.5 0.0 7.6e-18 64.3 0.0 1.7 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 CAR27949.1 - 8.4e-13 47.6 0.1 1.5e-12 46.8 0.1 1.4 1 0 0 1 1 1 1 UBA-like domain C2-set PF05790.10 CAR27949.1 - 0.0037 17.1 0.1 0.0084 16.0 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin C2-set domain Bravo_FIGEY PF13882.1 CAR27949.1 - 4.1 8.4 9.5 0.21 12.5 1.6 2.6 2 1 0 2 2 2 0 Bravo-like intracellular region Sas10_Utp3 PF04000.10 CAR27950.1 - 1.1e-06 28.6 2.3 1.1e-06 28.6 1.6 1.9 2 1 0 2 2 2 1 Sas10/Utp3/C1D family Peroxin-3 PF04882.7 CAR27952.1 - 4.7e-104 348.5 8.5 6.1e-104 348.1 5.9 1.1 1 0 0 1 1 1 1 Peroxin-3 Skp1 PF01466.14 CAR27953.1 - 1.9e-36 123.9 0.7 2.9e-36 123.3 0.5 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 CAR27953.1 - 2e-14 53.4 0.1 1.1e-13 51.0 0.1 2.2 2 1 0 2 2 2 1 Skp1 family, tetramerisation domain DUF1743 PF08489.6 CAR27953.1 - 0.08 12.6 0.1 0.17 11.6 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1743) GRAM PF02893.15 CAR27954.1 - 6.8e-17 60.7 0.0 1.3e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 GRAM domain adh_short PF00106.20 CAR27955.1 - 3.7e-17 62.7 0.0 5.5e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CAR27955.1 - 6.5e-09 35.6 0.0 1.1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CAR27955.1 - 4.9e-05 22.8 0.0 7.3e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 CAR27955.1 - 0.0026 17.5 0.0 0.0036 17.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.21 CAR27955.1 - 0.0075 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase THF_DHG_CYH_C PF02882.14 CAR27955.1 - 0.021 13.9 0.0 0.037 13.0 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 CAR27955.1 - 0.026 14.5 0.0 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 CAR27955.1 - 0.09 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Swi5 PF07061.6 CAR27956.1 - 1.8e-22 78.8 2.0 2.1e-22 78.6 1.4 1.0 1 0 0 1 1 1 1 Swi5 GAS PF13851.1 CAR27956.1 - 0.0092 15.2 3.6 0.01 15.0 2.5 1.0 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding ApoLp-III PF07464.6 CAR27956.1 - 0.013 15.4 1.2 0.018 15.1 0.6 1.4 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) PEP-utilisers_N PF05524.8 CAR27956.1 - 0.017 14.9 1.4 0.019 14.7 1.0 1.3 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal RsbU_N PF08673.5 CAR27956.1 - 0.036 14.0 0.2 0.05 13.6 0.1 1.3 1 0 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain DUF4659 PF15558.1 CAR27956.1 - 0.047 12.3 5.1 0.061 11.9 0.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4659) HALZ PF02183.13 CAR27956.1 - 0.054 13.2 2.3 0.096 12.4 0.6 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper DASH_Dad2 PF08654.5 CAR27956.1 - 0.059 13.3 1.7 0.08 12.9 1.0 1.4 1 1 0 1 1 1 0 DASH complex subunit Dad2 Occludin_ELL PF07303.8 CAR27956.1 - 0.062 14.0 1.2 0.079 13.6 0.9 1.2 1 0 0 1 1 1 0 Occludin homology domain UPF0242 PF06785.6 CAR27956.1 - 0.062 11.9 3.0 0.071 11.7 2.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) bZIP_Maf PF03131.12 CAR27956.1 - 0.089 13.1 1.2 0.16 12.2 0.8 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor EURL PF06937.6 CAR27956.1 - 0.09 12.1 3.4 0.12 11.7 0.8 1.8 1 1 1 2 2 2 0 EURL protein DUF2935 PF11155.3 CAR27956.1 - 0.1 12.6 0.7 0.12 12.4 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) Herpes_UL6 PF01763.11 CAR27956.1 - 0.11 10.6 0.8 0.11 10.7 0.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like FtsL PF04999.8 CAR27956.1 - 0.11 12.2 0.9 0.15 11.8 0.6 1.2 1 0 0 1 1 1 0 Cell division protein FtsL CENP-F_leu_zip PF10473.4 CAR27956.1 - 0.11 12.2 4.1 0.13 12.0 2.9 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Macoilin PF09726.4 CAR27956.1 - 0.17 10.1 1.7 0.18 10.0 1.2 1.0 1 0 0 1 1 1 0 Transmembrane protein bZIP_1 PF00170.16 CAR27956.1 - 0.31 11.0 2.9 0.47 10.4 0.5 2.0 2 0 0 2 2 2 0 bZIP transcription factor Atg14 PF10186.4 CAR27956.1 - 0.34 9.7 4.1 0.39 9.6 2.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Viral_P18 PF04521.8 CAR27956.1 - 0.35 10.3 3.6 0.25 10.7 1.2 1.7 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DivIC PF04977.10 CAR27956.1 - 0.7 9.4 5.9 0.39 10.2 1.8 1.9 1 1 1 2 2 2 0 Septum formation initiator Pkinase PF00069.20 CAR27957.1 - 1.7e-44 151.9 0.0 3.3e-44 151.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 CAR27957.1 - 5.6e-44 149.0 0.5 1.1e-43 148.1 0.4 1.5 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 CAR27957.1 - 3.3e-22 78.7 0.0 2.4e-21 75.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.1 CAR27957.1 - 0.00023 20.6 0.0 0.0036 16.8 0.0 2.5 1 1 0 1 1 1 1 PQQ-like domain PQQ PF01011.16 CAR27957.1 - 0.00081 18.8 0.0 0.16 11.5 0.0 2.9 2 0 0 2 2 2 1 PQQ enzyme repeat Kdo PF06293.9 CAR27957.1 - 0.079 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ_3 PF13570.1 CAR27957.1 - 0.23 11.7 1.7 20 5.6 0.0 3.5 4 0 0 4 4 4 0 PQQ-like domain DUF3120 PF11318.3 CAR27957.1 - 0.31 11.2 0.0 0.55 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) Cnd3 PF12719.2 CAR27958.1 - 2.7e-100 335.2 4.9 2.7e-100 335.2 3.4 3.4 4 0 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 CAR27958.1 - 1e-09 38.5 0.2 1.3e-07 31.8 0.0 3.6 3 2 1 4 4 4 2 HEAT repeats HEAT PF02985.17 CAR27958.1 - 1.9e-08 33.7 0.4 0.68 10.1 0.0 5.8 5 0 0 5 5 5 3 HEAT repeat FAD_syn PF06574.7 CAR27958.1 - 0.00097 18.7 0.4 0.0025 17.4 0.1 1.8 2 0 0 2 2 2 1 FAD synthetase Cnd1 PF12717.2 CAR27958.1 - 0.0079 16.0 1.6 0.0079 16.0 1.1 3.6 2 2 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 CAR27958.1 - 0.036 14.4 0.6 1.4 9.3 0.1 3.7 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region WD40 PF00400.27 CAR27959.1 - 5.2e-16 57.8 14.1 0.066 13.1 0.0 9.2 10 0 0 10 10 10 6 WD domain, G-beta repeat ABA_GPCR PF12430.3 CAR27960.1 - 2.7e-51 173.5 5.7 2.7e-51 173.5 4.0 2.7 2 1 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 CAR27960.1 - 4.8e-19 68.1 0.2 1.2e-18 66.8 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3735) FYVE PF01363.16 CAR27961.1 - 2.6e-15 56.0 23.2 2e-13 49.9 2.2 2.8 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.3 CAR27961.1 - 1.8e-06 27.4 0.4 3.8e-06 26.3 0.2 1.5 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-ribbon_3 PF13248.1 CAR27961.1 - 0.97 8.7 6.8 5.4 6.3 1.3 2.8 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2HC5 PF06221.8 CAR27961.1 - 3.6 7.4 20.7 0.96 9.2 0.5 3.9 4 0 0 4 4 4 0 Putative zinc finger motif, C2HC5-type DUF702 PF05142.7 CAR27961.1 - 4.3 7.5 11.7 0.24 11.5 3.4 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF702) MIF4G PF02854.14 CAR27962.1 - 5.7e-37 127.1 43.7 3.5e-18 65.7 2.1 4.8 4 1 0 4 4 4 3 MIF4G domain Upf2 PF04050.9 CAR27962.1 - 3.4e-15 56.2 48.6 4.1e-13 49.4 33.7 2.7 1 1 0 1 1 1 1 Up-frameshift suppressor 2 Daxx PF03344.10 CAR27962.1 - 0.87 7.9 38.2 1.6 7.1 26.4 1.3 1 0 0 1 1 1 0 Daxx Family Herpes_LMP1 PF05297.6 CAR27962.1 - 1.9 7.3 7.1 2.2 7.1 3.2 2.0 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) SpoIIE PF07228.7 CAR27963.1 - 3.7e-37 127.9 0.0 4.7e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 CAR27963.1 - 6.8e-08 32.2 0.0 0.00017 21.0 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 CAR27963.1 - 7.7e-05 22.1 0.2 0.00025 20.5 0.2 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C ATP-synt_E PF05680.7 CAR27964.1 - 2.4e-12 46.6 0.0 2.6e-12 46.5 0.0 1.0 1 0 0 1 1 1 1 ATP synthase E chain PBP PF01161.15 CAR27965.1 - 9.3e-12 45.0 0.2 1.9e-11 44.0 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Peptidase_M1 PF01433.15 CAR27966.1 - 1.7e-123 412.5 5.5 8.1e-122 407.0 3.8 2.1 1 1 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 CAR27966.1 - 6.4e-21 74.9 0.0 9.9e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 CAR27966.1 - 3.4e-16 59.4 0.1 7.7e-16 58.3 0.1 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily Abhydrolase_6 PF12697.2 CAR27967.1 - 5.6e-18 65.6 0.0 7.8e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAR27967.1 - 2.6e-11 43.5 0.0 1e-10 41.6 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CAR27967.1 - 2.9e-07 30.3 0.0 6.2e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CAR27967.1 - 2.1e-05 24.2 0.0 6.4e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase Lipase_3 PF01764.20 CAR27967.1 - 0.00054 19.5 0.1 0.0012 18.4 0.1 1.6 1 1 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 CAR27967.1 - 0.0014 18.0 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Thioesterase PF00975.15 CAR27967.1 - 0.0093 16.2 0.2 0.11 12.6 0.2 2.1 1 1 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 CAR27967.1 - 0.022 14.3 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF2305 PF10230.4 CAR27967.1 - 0.079 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Cutinase PF01083.17 CAR27967.1 - 0.13 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Cutinase CN_hydrolase PF00795.17 CAR27968.1 - 2.2e-28 98.8 0.0 3.5e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 CAR27968.1 - 2.8e-23 82.1 0.0 1.3e-22 79.9 0.0 1.9 1 1 0 1 1 1 1 NAD synthase Asparaginase PF00710.15 CAR27969.1 - 3e-72 243.1 0.0 3.8e-72 242.8 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Oxysterol_BP PF01237.13 CAR27970.1 - 3.3e-98 328.4 0.3 3.3e-98 328.4 0.2 1.9 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 CAR27970.1 - 5.8e-29 99.9 1.4 1.3e-28 98.9 0.4 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain 2-Hacid_dh_C PF02826.14 CAR27971.1 - 7.6e-40 135.9 0.0 4.2e-39 133.5 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CAR27971.1 - 1.1e-19 70.1 0.1 1.7e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CAR27971.1 - 0.0025 17.6 0.0 0.0067 16.2 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.13 CAR27971.1 - 0.051 13.5 0.2 7.4 6.6 0.0 3.0 2 1 1 3 3 3 0 TrkA-N domain Shikimate_DH PF01488.15 CAR27971.1 - 0.068 13.2 0.2 11 6.1 0.0 2.9 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ResIII PF04851.10 CAR27972.1 - 2.4e-27 95.9 0.1 2.4e-27 95.9 0.1 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CAR27972.1 - 1.9e-16 60.0 0.2 5e-16 58.6 0.1 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR27972.1 - 5.1e-15 55.0 0.1 8.7e-14 51.1 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF2075 PF09848.4 CAR27972.1 - 9.1e-06 24.8 0.0 2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SNF2_N PF00176.18 CAR27972.1 - 0.00057 18.7 0.2 0.0013 17.6 0.1 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 CAR27972.1 - 0.0029 17.7 0.2 0.027 14.6 0.1 2.6 2 1 0 2 2 2 1 AAA domain Helicase_C_2 PF13307.1 CAR27972.1 - 0.026 14.4 0.1 0.62 9.9 0.0 3.0 3 0 0 3 3 3 0 Helicase C-terminal domain AAA_11 PF13086.1 CAR27972.1 - 0.073 12.6 3.9 0.42 10.1 0.1 2.8 3 1 1 4 4 4 0 AAA domain Ocnus PF05005.10 CAR27972.1 - 0.1 12.5 0.0 0.3 10.9 0.0 1.8 1 0 0 1 1 1 0 Janus/Ocnus family (Ocnus) DUF2731 PF10806.3 CAR27973.1 - 1.4e-41 141.6 0.8 2.1e-41 141.0 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2731) Tcf25 PF04910.9 CAR27974.1 - 4.8e-77 259.3 0.2 8.6e-77 258.4 0.2 1.4 1 0 0 1 1 1 1 Transcriptional repressor TCF25 FLO_LFY PF01698.11 CAR27974.1 - 2.7 6.7 13.6 4.4 6.0 9.5 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein GAGA_bind PF06217.7 CAR27974.1 - 5.6 6.8 11.8 9.1 6.1 8.2 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Ipi1_N PF12333.3 CAR27975.1 - 2.1e-26 91.8 0.2 2.1e-26 91.8 0.1 2.5 2 1 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation HEAT PF02985.17 CAR27975.1 - 0.005 16.8 0.0 13 6.2 0.0 3.7 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 CAR27975.1 - 0.067 13.4 0.0 0.31 11.3 0.0 2.2 1 1 0 1 1 1 0 HEAT repeats V-ATPase_H_C PF11698.3 CAR27975.1 - 0.13 12.1 1.0 0.51 10.2 0.1 2.4 3 0 0 3 3 3 0 V-ATPase subunit H DUF3464 PF11947.3 CAR27975.1 - 0.47 9.8 3.6 1.3 8.4 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) Acetyltransf_1 PF00583.19 CAR27976.1 - 1.8e-16 59.9 0.6 2.5e-16 59.4 0.4 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CAR27976.1 - 3.7e-08 33.4 0.1 4.8e-08 33.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CAR27976.1 - 7.3e-08 32.5 0.0 9e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CAR27976.1 - 3.4e-06 27.0 0.1 3.8e-06 26.9 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CAR27976.1 - 9.8e-06 25.2 0.1 1.6e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 CAR27976.1 - 9.1e-05 22.3 0.0 0.00011 22.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CAR27976.1 - 0.0032 17.6 0.0 0.0035 17.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CAR27976.1 - 0.0037 17.1 0.0 0.0048 16.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CAR27976.1 - 0.075 12.9 0.1 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DnaJ PF00226.26 CAR27977.1 - 3e-18 65.3 0.4 6.7e-18 64.1 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.11 CAR27977.1 - 1.3e-15 57.4 0.2 2.1e-13 50.1 0.0 2.2 1 1 1 2 2 2 2 Sec63 Brl domain OppC_N PF12911.2 CAR27977.1 - 0.14 11.5 4.8 1.4 8.3 0.0 3.2 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C DUF2457 PF10446.4 CAR27977.1 - 0.51 9.0 18.2 0.7 8.5 10.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) FAM176 PF14851.1 CAR27977.1 - 8.7 6.0 7.9 19 4.8 5.4 1.6 1 0 0 1 1 1 0 FAM176 family TAP_C PF03943.8 CAR27978.1 - 1.3e-17 62.9 0.3 4.3e-17 61.2 0.0 2.0 2 0 0 2 2 2 1 TAP C-terminal domain LRR_4 PF12799.2 CAR27978.1 - 7.7e-06 25.4 6.1 2.4e-05 23.8 1.1 2.9 1 1 1 2 2 2 1 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 CAR27978.1 - 0.00012 21.7 0.5 0.00022 20.8 0.4 1.4 1 0 0 1 1 1 1 Leucine-rich repeat Myb_CC_LHEQLE PF14379.1 CAR27978.1 - 0.013 15.0 0.1 0.035 13.7 0.1 1.7 1 0 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif LRR_8 PF13855.1 CAR27978.1 - 0.073 12.8 1.5 0.27 11.0 1.1 2.0 1 0 0 1 1 1 0 Leucine rich repeat LRR_6 PF13516.1 CAR27978.1 - 0.077 13.1 4.0 7.9 6.8 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.28 CAR27978.1 - 2.3 8.5 7.8 7.3 7.0 0.1 4.4 5 0 0 5 5 5 0 Leucine Rich Repeat Cyt-b5 PF00173.23 CAR27980.1 - 1.4e-11 43.9 0.0 1.9e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PX PF00787.19 CAR27981.1 - 3.4e-05 23.6 0.1 6.6e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 CAR27981.1 - 0.0021 17.3 6.7 0.0035 16.6 4.7 1.3 1 0 0 1 1 1 1 Vps5 C terminal like CENP-H PF05837.7 CAR27981.1 - 2.6 8.2 8.5 3.3 7.9 0.1 3.2 2 1 1 3 3 3 0 Centromere protein H (CENP-H) GTP_EFTU PF00009.22 CAR27982.1 - 5.9e-63 211.7 0.4 8.5e-63 211.1 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CAR27982.1 - 5.8e-37 125.9 0.0 1.9e-36 124.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 CAR27982.1 - 2.8e-22 78.3 0.0 6.7e-22 77.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CAR27982.1 - 6.1e-14 51.8 0.5 3.1e-13 49.6 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 CAR27982.1 - 1.3e-13 50.5 0.0 4.1e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 CAR27982.1 - 3.9e-05 23.5 0.2 8.2e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SUKH-4 PF14435.1 CAR27982.1 - 0.089 12.4 0.0 0.27 10.9 0.0 1.8 1 0 0 1 1 1 0 SUKH-4 immunity protein ERCC4 PF02732.10 CAR27983.1 - 4.7e-23 81.5 0.5 8e-23 80.7 0.3 1.4 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 CAR27983.1 - 0.03 14.4 0.0 0.11 12.7 0.0 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix domain Sugar_tr PF00083.19 CAR27984.1 - 3.5e-91 306.0 24.8 8.6e-51 172.9 6.0 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CAR27984.1 - 1.5e-24 86.3 35.2 4.7e-21 74.8 9.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2 PF04550.7 CAR27984.1 - 0.11 12.5 7.3 0.13 12.3 2.2 2.7 2 0 0 2 2 2 0 Phage holin family 2 BAR PF03114.13 CAR27985.1 - 1.3e-58 198.2 5.0 1.6e-58 197.9 3.4 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 CAR27985.1 - 8.5e-14 50.6 0.0 1.5e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CAR27985.1 - 3.2e-13 49.0 0.1 5.7e-13 48.2 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CAR27985.1 - 5.1e-09 35.4 0.0 9.4e-09 34.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF1931 PF09123.6 CAR27985.1 - 0.12 12.3 0.2 0.43 10.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1931) RhoGAP PF00620.22 CAR27986.1 - 3.4e-32 111.1 1.1 1.3e-20 73.5 0.0 2.9 3 0 0 3 3 3 2 RhoGAP domain ThiF PF00899.16 CAR27987.1 - 2.3e-34 118.1 0.0 5e-34 117.0 0.0 1.6 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 CAR27987.1 - 7.6e-26 89.4 0.8 2.4e-25 87.8 0.5 1.9 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CAR27987.1 - 4e-21 74.1 3.9 7.5e-21 73.2 2.7 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 CAR27987.1 - 0.00018 21.5 1.2 0.00018 21.5 0.8 2.0 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Utp13 PF08625.6 CAR27987.1 - 0.022 14.3 0.6 0.048 13.3 0.4 1.5 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain Polysacc_synt_2 PF02719.10 CAR27987.1 - 0.13 11.1 0.0 0.26 10.1 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein CDC45 PF02724.9 CAR27987.1 - 0.39 8.6 6.1 0.72 7.8 4.2 1.3 1 0 0 1 1 1 0 CDC45-like protein Iso_dh PF00180.15 CAR27988.1 - 1.5e-99 333.3 0.1 1.8e-99 332.9 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF2587 PF10759.4 CAR27988.1 - 0.064 12.6 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) UBA PF00627.26 CAR27990.1 - 4.5e-08 32.7 0.0 1.3e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 UBA/TS-N domain CUE PF02845.11 CAR27990.1 - 3.3e-05 23.2 0.0 0.00035 19.9 0.0 2.5 2 0 0 2 2 2 1 CUE domain UBA_4 PF14555.1 CAR27990.1 - 4.5e-05 22.8 0.0 0.00011 21.6 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain GldM_N PF12081.3 CAR27990.1 - 0.014 14.9 2.8 0.025 14.0 2.0 1.3 1 0 0 1 1 1 0 GldM N-terminal domain HSF_DNA-bind PF00447.12 CAR27991.1 - 1.6e-34 118.1 2.1 1.6e-34 118.1 1.4 2.5 2 1 0 2 2 2 1 HSF-type DNA-binding DUF4407 PF14362.1 CAR27991.1 - 3.2 6.6 4.6 5.3 5.8 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RR_TM4-6 PF06459.7 CAR27991.1 - 8 6.2 13.0 7 6.4 0.2 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Actin PF00022.14 CAR27992.1 - 1.8e-25 89.2 0.0 3.8e-19 68.3 0.0 3.7 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 CAR27992.1 - 0.0014 17.3 0.0 0.038 12.5 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein PilM_2 PF11104.3 CAR27992.1 - 0.077 11.8 0.1 3.8 6.2 0.0 2.8 3 0 0 3 3 3 0 Type IV pilus assembly protein PilM; BAR_3_WASP_bdg PF10456.4 CAR27992.1 - 0.21 10.7 3.1 0.38 9.9 0.4 2.2 2 0 0 2 2 2 0 WASP-binding domain of Sorting nexin protein Ligase_CoA PF00549.14 CAR27993.1 - 5.1e-24 84.6 0.2 8e-24 83.9 0.1 1.3 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.14 CAR27993.1 - 9.2e-24 83.7 3.1 4e-23 81.7 0.8 2.2 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.1 CAR27993.1 - 3.3e-06 26.7 0.0 6.3e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 CAR27993.1 - 0.00033 20.8 0.0 0.00077 19.6 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain TPK_catalytic PF04263.11 CAR27994.1 - 2.5e-22 78.7 0.0 5.9e-18 64.6 0.0 2.2 1 1 1 2 2 2 2 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 CAR27994.1 - 2.3e-12 46.4 0.1 4.9e-12 45.3 0.1 1.5 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Baculo_p48 PF04878.8 CAR27994.1 - 0.0029 16.5 0.0 0.0043 16.0 0.0 1.2 1 0 0 1 1 1 1 Baculovirus P48 protein TFIID-18kDa PF02269.11 CAR27995.1 - 2.5e-36 123.3 0.8 5.1e-35 119.1 0.1 2.5 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit AAA PF00004.24 CAR27996.1 - 0.0014 18.8 0.6 0.009 16.2 0.0 2.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Caps_synth_GfcC PF06251.6 CAR27996.1 - 0.0066 15.6 0.5 0.064 12.4 0.0 2.2 2 0 0 2 2 2 1 Capsule biosynthesis GfcC KH_1 PF00013.24 CAR27997.1 - 0.00075 19.0 1.4 0.0012 18.4 0.3 1.8 2 0 0 2 2 2 1 KH domain MDM31_MDM32 PF08118.6 CAR27998.1 - 1.2e-72 244.9 22.1 5.4e-34 117.5 3.1 4.0 2 1 2 4 4 4 4 Yeast mitochondrial distribution and morphology (MDM) proteins DUF748 PF05359.6 CAR27998.1 - 0.063 13.2 0.0 0.25 11.3 0.0 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF748) G-patch_2 PF12656.2 CAR27999.1 - 2.8e-19 68.7 0.3 2.8e-19 68.7 0.2 2.5 2 2 0 2 2 2 1 DExH-box splicing factor binding site She9_MDM33 PF05546.6 CAR28000.1 - 1.2e-88 296.1 15.1 1.2e-88 296.1 10.5 2.0 2 0 0 2 2 2 1 She9 / Mdm33 family PsbH PF00737.15 CAR28000.1 - 0.0032 17.0 0.4 0.0059 16.1 0.3 1.3 1 0 0 1 1 1 1 Photosystem II 10 kDa phosphoprotein DUF883 PF05957.8 CAR28000.1 - 0.006 16.9 9.8 0.43 11.0 0.3 3.8 3 1 0 3 3 3 2 Bacterial protein of unknown function (DUF883) CENP-Q PF13094.1 CAR28000.1 - 0.0076 16.2 11.5 0.0076 16.2 7.9 3.1 2 1 2 4 4 4 1 CENP-Q, a CENPA-CAD centromere complex subunit DIRP PF06584.8 CAR28000.1 - 0.043 13.6 0.3 0.043 13.6 0.2 2.8 2 1 0 2 2 2 0 DIRP Reo_sigmaC PF04582.7 CAR28000.1 - 0.062 12.4 0.9 4.4 6.3 0.0 2.3 2 0 0 2 2 2 0 Reovirus sigma C capsid protein AAA PF00004.24 CAR28001.1 - 1.3e-45 154.7 0.0 3.3e-45 153.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CAR28001.1 - 6.2e-08 32.7 0.0 1.3e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CAR28001.1 - 2e-07 30.7 0.1 9.4e-07 28.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CAR28001.1 - 9e-07 29.0 0.1 3.8e-06 27.0 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CAR28001.1 - 2.4e-06 27.7 0.4 0.00016 21.8 0.2 2.8 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 CAR28001.1 - 0.00014 20.8 0.0 0.00024 20.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 CAR28001.1 - 0.00036 20.4 0.0 0.00086 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CAR28001.1 - 0.00056 19.0 0.0 0.0013 17.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 CAR28001.1 - 0.001 18.7 0.0 0.0065 16.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CAR28001.1 - 0.001 19.9 0.0 0.0034 18.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CAR28001.1 - 0.0018 18.0 0.1 0.0042 16.8 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 CAR28001.1 - 0.0018 17.7 0.8 0.055 12.8 0.1 2.3 1 1 1 2 2 2 1 AAA domain NTPase_1 PF03266.10 CAR28001.1 - 0.0018 17.9 0.0 0.0051 16.5 0.0 1.8 2 0 0 2 2 1 1 NTPase AAA_11 PF13086.1 CAR28001.1 - 0.0019 17.7 0.0 0.0086 15.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CAR28001.1 - 0.0022 17.1 0.0 0.004 16.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin RNA_helicase PF00910.17 CAR28001.1 - 0.0025 17.9 0.0 0.0052 16.9 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.1 CAR28001.1 - 0.0026 17.3 0.0 0.0059 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 CAR28001.1 - 0.004 16.7 0.0 0.013 15.1 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 CAR28001.1 - 0.0041 17.0 0.0 0.0083 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 CAR28001.1 - 0.0042 15.8 0.0 0.0077 14.9 0.0 1.4 1 1 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 CAR28001.1 - 0.0054 15.9 0.1 0.016 14.3 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 CAR28001.1 - 0.0056 16.6 0.0 0.016 15.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain UPF0079 PF02367.12 CAR28001.1 - 0.0065 16.0 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 CAR28001.1 - 0.0072 16.0 0.1 0.064 12.9 0.0 2.3 2 0 0 2 2 2 1 NACHT domain Sigma54_activat PF00158.21 CAR28001.1 - 0.0081 15.6 0.0 0.21 11.0 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 CAR28001.1 - 0.0094 15.3 0.0 0.028 13.8 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein Arch_ATPase PF01637.13 CAR28001.1 - 0.016 14.8 0.1 0.17 11.5 0.0 2.3 1 1 0 2 2 2 0 Archaeal ATPase AAA_18 PF13238.1 CAR28001.1 - 0.024 14.9 0.0 0.064 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 CAR28001.1 - 0.05 13.9 0.1 2.3 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 CAR28001.1 - 0.083 12.3 0.1 1.1 8.6 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 CAR28001.1 - 0.12 11.2 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Glyco_transf_22 PF03901.12 CAR28002.1 - 1.8e-66 224.8 22.9 2.1e-66 224.6 15.9 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family IBN_N PF03810.14 CAR28003.1 - 4.7e-18 64.8 1.3 1.7e-17 63.1 0.8 2.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain CBFD_NFYB_HMF PF00808.18 CAR28004.1 - 9.3e-14 51.2 1.3 1.5e-13 50.5 0.9 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PcrB PF01884.12 CAR28004.1 - 0.034 13.3 0.1 0.048 12.9 0.1 1.2 1 0 0 1 1 1 0 PcrB family Utp12 PF04003.7 CAR28005.1 - 9.5e-20 70.5 2.2 2e-19 69.5 1.5 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family DUF2457 PF10446.4 CAR28005.1 - 4.4 5.9 16.4 7 5.2 11.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pribosyltran PF00156.22 CAR28006.1 - 7.2e-10 38.6 0.0 1.2e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Fe-ADH PF00465.14 CAR28006.1 - 0.054 12.1 0.0 0.083 11.5 0.0 1.3 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase DUF768 PF05589.6 CAR28006.1 - 0.089 12.7 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF768) 3Beta_HSD PF01073.14 CAR28006.1 - 0.095 11.3 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family IU_nuc_hydro PF01156.14 CAR28007.1 - 6.9e-82 275.1 0.0 7.8e-82 274.9 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase p450 PF00067.17 CAR28008.1 - 1.5e-60 205.0 0.1 1.9e-60 204.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 DIT1_PvcA PF05141.7 CAR28009.1 - 8.9e-103 343.4 0.1 5e-102 340.9 0.0 1.9 2 0 0 2 2 2 1 Pyoverdine/dityrosine biosynthesis protein SHS2_Rpb7-N PF03876.12 CAR28010.1 - 2e-17 63.0 0.0 3.9e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 CAR28010.1 - 1.2e-15 57.2 0.1 1.8e-15 56.7 0.1 1.2 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 CAR28010.1 - 1.9e-06 28.0 0.0 3.2e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 Ribosomal_L13 PF00572.13 CAR28011.1 - 1.7e-42 144.4 0.1 2.1e-42 144.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 RNA_pol_Rpb2_6 PF00562.23 CAR28012.1 - 4.5e-126 420.6 0.7 1.1e-125 419.4 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CAR28012.1 - 4.8e-72 241.1 0.1 7.4e-72 240.5 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 CAR28012.1 - 1.7e-52 177.6 0.0 3.4e-52 176.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 CAR28012.1 - 2.8e-30 104.4 0.0 7.1e-30 103.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 CAR28012.1 - 2.5e-28 97.6 1.9 3.3e-28 97.2 0.3 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 CAR28012.1 - 5.8e-22 77.2 0.1 1.8e-21 75.6 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 CAR28012.1 - 5.1e-17 61.5 1.5 1.2e-16 60.3 1.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Ribosomal_L23 PF00276.15 CAR28013.1 - 7.8e-23 80.2 0.0 1.3e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 ABC2_membrane PF01061.19 CAR28015.1 - 3.8e-81 271.2 54.6 1.4e-44 151.7 14.5 2.7 3 0 0 3 3 2 2 ABC-2 type transporter PDR_CDR PF06422.7 CAR28015.1 - 1.2e-42 143.7 4.6 2.9e-38 129.6 0.2 2.7 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 CAR28015.1 - 3.8e-39 134.1 0.2 3.6e-17 62.9 0.0 3.5 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.1 CAR28015.1 - 1.7e-19 69.6 0.0 7.4e-19 67.6 0.0 2.1 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 CAR28015.1 - 1.6e-10 40.7 0.1 1.4e-06 27.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CAR28015.1 - 2.9e-06 27.3 0.2 0.00036 20.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain ABC2_membrane_3 PF12698.2 CAR28015.1 - 7.8e-06 25.1 32.0 0.0088 15.1 14.7 2.9 2 1 0 2 2 2 2 ABC-2 family transporter protein cobW PF02492.14 CAR28015.1 - 1.6e-05 24.4 1.7 0.061 12.7 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 CAR28015.1 - 2.5e-05 23.9 0.1 0.096 12.3 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.1 CAR28015.1 - 6.1e-05 23.3 0.9 0.2 11.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 CAR28015.1 - 0.00013 21.2 0.0 0.0033 16.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CAR28015.1 - 0.0002 21.5 0.4 0.49 10.5 0.0 3.3 4 0 0 4 4 3 1 AAA domain UPF0079 PF02367.12 CAR28015.1 - 0.00023 20.7 0.7 0.27 10.8 0.2 2.5 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 CAR28015.1 - 0.00055 19.6 0.9 0.38 10.5 0.1 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_29 PF13555.1 CAR28015.1 - 0.00085 18.8 2.8 0.0071 15.8 0.4 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.14 CAR28015.1 - 0.00086 18.6 0.0 0.17 11.1 0.0 2.8 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CAR28015.1 - 0.0011 19.3 3.3 0.018 15.3 0.0 3.4 4 0 0 4 4 3 1 AAA domain AAA_33 PF13671.1 CAR28015.1 - 0.0014 18.4 1.6 0.46 10.3 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA PF00004.24 CAR28015.1 - 0.0024 18.0 0.0 1.8 8.7 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CAR28015.1 - 0.0035 17.3 5.5 0.065 13.1 0.2 3.3 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.1 CAR28015.1 - 0.0052 16.7 0.0 0.39 10.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CAR28015.1 - 0.011 16.5 1.3 2.2 9.1 0.0 3.1 3 0 0 3 3 2 0 AAA domain Arch_ATPase PF01637.13 CAR28015.1 - 0.017 14.8 0.0 1.8 8.1 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase Miro PF08477.8 CAR28015.1 - 0.025 15.0 0.2 7.6 7.0 0.0 2.8 2 1 0 2 2 2 0 Miro-like protein Viral_helicase1 PF01443.13 CAR28015.1 - 0.042 13.3 0.2 9.2 5.7 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 CAR28015.1 - 0.083 12.3 0.3 16 4.8 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain PduV-EutP PF10662.4 CAR28015.1 - 0.086 12.3 0.6 1.4 8.3 0.2 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation T2SE PF00437.15 CAR28015.1 - 0.096 11.5 0.1 1.4 7.7 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.1 CAR28015.1 - 0.12 11.9 0.9 4.8 6.7 0.3 2.3 2 0 0 2 2 2 0 AAA domain OCD_Mu_crystall PF02423.10 CAR28015.1 - 0.21 10.3 0.0 1.3 7.7 0.0 2.0 2 0 0 2 2 2 0 Ornithine cyclodeaminase/mu-crystallin family FtsK_SpoIIIE PF01580.13 CAR28015.1 - 0.23 10.8 0.1 13 5.2 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family NB-ARC PF00931.17 CAR28015.1 - 0.31 9.8 2.0 6.6 5.4 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain NTPase_1 PF03266.10 CAR28015.1 - 0.34 10.5 1.4 39 3.8 0.1 3.2 3 0 0 3 3 3 0 NTPase ABC2_membrane PF01061.19 CAR28016.1 - 6.4e-79 263.9 54.2 7.1e-42 142.9 15.7 2.7 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 CAR28016.1 - 1.7e-38 130.4 4.9 5.9e-34 115.8 0.1 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 CAR28016.1 - 2.2e-38 131.6 0.1 4.2e-18 65.9 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_trans_N PF14510.1 CAR28016.1 - 3e-20 72.0 0.0 1.1e-19 70.2 0.0 1.9 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 CAR28016.1 - 6.1e-07 29.0 0.0 0.00019 20.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 CAR28016.1 - 1.2e-05 24.8 2.7 0.0046 16.4 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 CAR28016.1 - 1.8e-05 24.7 0.4 0.00095 19.1 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 CAR28016.1 - 3.8e-05 22.9 0.0 0.001 18.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 CAR28016.1 - 8.2e-05 22.9 0.3 0.062 13.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 CAR28016.1 - 0.00011 22.0 0.0 0.042 13.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 CAR28016.1 - 0.00017 20.8 0.0 0.016 14.4 0.0 2.9 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_19 PF13245.1 CAR28016.1 - 0.00019 21.0 0.2 0.68 9.7 0.0 2.5 2 0 0 2 2 2 2 Part of AAA domain AAA_22 PF13401.1 CAR28016.1 - 0.00087 19.4 0.0 0.54 10.4 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.1 CAR28016.1 - 0.0011 18.4 1.2 0.0072 15.8 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.7 CAR28016.1 - 0.0016 18.1 0.1 2 8.0 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_23 PF13476.1 CAR28016.1 - 0.0049 17.2 0.2 0.2 11.9 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CAR28016.1 - 0.0085 16.9 0.3 1.8 9.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain UPF0079 PF02367.12 CAR28016.1 - 0.012 15.1 0.3 0.74 9.4 0.1 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 CAR28016.1 - 0.024 14.5 4.5 0.5 10.3 0.1 3.3 3 0 0 3 3 3 0 AAA domain AAA_21 PF13304.1 CAR28016.1 - 0.029 14.3 3.0 0.27 11.1 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA PF00004.24 CAR28016.1 - 0.042 14.0 0.0 9 6.5 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 CAR28016.1 - 0.056 13.1 0.0 4.6 6.8 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase PduV-EutP PF10662.4 CAR28016.1 - 0.077 12.4 0.9 2.5 7.5 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 CAR28016.1 - 0.15 11.6 0.5 7.6 6.0 0.2 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 CAR28016.1 - 0.38 10.4 0.7 29 4.3 0.0 2.9 3 0 0 3 3 3 0 NTPase ABC2_membrane_3 PF12698.2 CAR28016.1 - 0.66 8.9 40.4 0.67 8.9 14.5 3.0 2 2 0 2 2 2 0 ABC-2 family transporter protein ABC2_membrane PF01061.19 CAR28017.1 - 2.6e-81 271.8 47.0 2e-44 151.2 12.1 2.7 3 0 0 3 3 2 2 ABC-2 type transporter PDR_CDR PF06422.7 CAR28017.1 - 3.3e-42 142.3 5.2 4.2e-37 125.9 0.1 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 CAR28017.1 - 1.8e-37 128.6 0.0 6.1e-18 65.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 CAR28017.1 - 1.4e-23 82.7 0.0 5e-23 80.9 0.0 2.0 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 CAR28017.1 - 3.7e-08 33.0 0.1 3.5e-05 23.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CAR28017.1 - 1.2e-06 28.6 0.4 0.00016 21.6 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 CAR28017.1 - 1.5e-05 24.8 0.0 0.12 12.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 CAR28017.1 - 0.00011 21.4 0.1 0.0018 17.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CAR28017.1 - 0.00018 21.6 0.2 0.28 11.3 0.0 3.5 4 0 0 4 4 4 1 AAA domain AAA_19 PF13245.1 CAR28017.1 - 0.00024 20.8 0.4 0.44 10.3 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain AAA_17 PF13207.1 CAR28017.1 - 0.00058 20.6 0.4 2.3 9.0 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 CAR28017.1 - 0.00058 19.3 0.9 0.005 16.3 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 CAR28017.1 - 0.001 18.5 2.0 0.17 11.3 0.2 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 CAR28017.1 - 0.0011 18.6 0.0 1 8.9 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_21 PF13304.1 CAR28017.1 - 0.0024 17.8 0.0 0.13 12.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 CAR28017.1 - 0.0027 16.9 0.0 0.17 11.1 0.0 2.7 3 0 0 3 3 2 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 CAR28017.1 - 0.0046 17.2 1.8 0.55 10.5 0.0 3.1 3 0 0 3 3 2 1 AAA domain NTPase_1 PF03266.10 CAR28017.1 - 0.0074 16.0 0.9 3 7.5 0.1 3.2 3 0 0 3 3 3 1 NTPase UPF0079 PF02367.12 CAR28017.1 - 0.018 14.6 1.3 0.9 9.1 0.1 2.9 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 CAR28017.1 - 0.062 12.9 0.6 7.4 6.1 0.0 2.7 3 0 0 3 3 2 0 Archaeal ATPase AAA_28 PF13521.1 CAR28017.1 - 0.067 13.1 8.5 0.21 11.5 0.7 3.2 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.1 CAR28017.1 - 0.11 12.7 4.2 0.15 12.3 0.4 2.8 3 0 0 3 3 3 0 AAA domain DUF2536 PF10750.4 CAR28017.1 - 0.15 11.6 0.4 3.3 7.3 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2536) PduV-EutP PF10662.4 CAR28017.1 - 0.16 11.4 0.4 2.3 7.7 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation T2SE PF00437.15 CAR28017.1 - 0.18 10.6 0.1 4.5 6.0 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA PF00004.24 CAR28017.1 - 0.19 11.9 0.2 33 4.6 0.0 2.9 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) ABC2_membrane_3 PF12698.2 CAR28017.1 - 0.22 10.4 38.6 0.22 10.5 13.1 3.2 2 2 0 2 2 2 0 ABC-2 family transporter protein AAA_30 PF13604.1 CAR28017.1 - 3.4 7.2 6.9 8 5.9 0.5 2.7 3 0 0 3 3 3 0 AAA domain ISN1 PF06437.6 CAR28018.1 - 9.8e-176 584.4 0.0 1.1e-175 584.2 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Choline_transpo PF04515.7 CAR28019.1 - 4.5e-86 288.6 17.6 4.5e-86 288.6 12.2 2.1 1 1 1 2 2 2 1 Plasma-membrane choline transporter Xpo1 PF08389.7 CAR28020.1 - 5.2e-25 88.0 7.4 6.6e-25 87.7 0.4 4.0 5 0 0 5 5 5 1 Exportin 1-like protein IBN_N PF03810.14 CAR28020.1 - 4.1e-07 29.8 4.8 1.5e-05 24.7 0.9 3.3 2 1 0 2 2 2 2 Importin-beta N-terminal domain HEAT PF02985.17 CAR28020.1 - 0.016 15.2 0.0 8.8 6.7 0.1 3.7 2 0 0 2 2 2 0 HEAT repeat LSM PF01423.17 CAR28021.1 - 2.9e-14 52.3 0.1 3.5e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain TRAPPC9-Trs120 PF08626.6 CAR28023.1 - 0 1027.0 21.2 0 1025.5 14.7 1.6 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_12 PF13424.1 CAR28023.1 - 0.008 16.0 0.2 0.018 14.9 0.2 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Proteasome PF00227.21 CAR28024.1 - 3.9e-46 156.7 0.1 5e-46 156.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 CAR28024.1 - 3.5e-15 54.9 0.0 7.6e-15 53.8 0.0 1.6 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Formyl_trans_N PF00551.14 CAR28025.1 - 2.4e-52 177.1 0.0 2.8e-52 176.9 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase Glyco_trans_4_4 PF13579.1 CAR28025.1 - 0.0081 16.3 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain MannoseP_isomer PF01050.13 CAR28025.1 - 0.035 13.7 0.2 0.057 13.0 0.2 1.3 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase PINIT PF14324.1 CAR28026.1 - 2.6e-42 144.3 1.2 4.2e-42 143.6 0.8 1.3 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 CAR28026.1 - 5.3e-20 70.6 6.6 9.3e-20 69.8 4.6 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.22 CAR28026.1 - 4.2e-11 42.0 0.0 7.3e-11 41.3 0.0 1.4 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.3 CAR28026.1 - 0.00017 21.0 1.1 0.00034 20.0 0.8 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit YopE_N PF09020.5 CAR28026.1 - 0.00031 20.7 0.1 0.0013 18.7 0.1 2.0 1 0 0 1 1 1 1 YopE, N terminal zf-RING_UBOX PF13445.1 CAR28026.1 - 0.1 12.3 1.7 0.35 10.6 1.2 2.0 1 0 0 1 1 1 0 RING-type zinc-finger P30 PF07390.6 CAR28026.1 - 0.26 10.7 2.0 8.5 5.8 0.0 2.7 2 1 1 3 3 3 0 Mycoplasma P30 protein zf-C3HC4_2 PF13923.1 CAR28026.1 - 0.45 10.5 3.5 0.84 9.7 2.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ICMT PF04140.9 CAR28027.1 - 3.3e-29 100.9 0.3 7.3e-29 99.8 0.2 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CAR28027.1 - 1.1e-13 51.1 2.2 1.1e-13 51.1 1.5 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 CAR28027.1 - 3.3e-06 26.5 1.2 4.4e-06 26.1 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) zf-HIT PF04438.11 CAR28028.1 - 0.0003 20.3 8.6 0.00051 19.6 5.9 1.3 1 0 0 1 1 1 1 HIT zinc finger LsmAD PF06741.8 CAR28028.1 - 0.0082 16.2 5.4 0.028 14.5 2.2 2.4 1 1 1 2 2 2 1 LsmAD domain DARPP-32 PF05395.7 CAR28028.1 - 0.21 11.7 3.6 2.5 8.2 2.5 2.1 1 1 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 Carn_acyltransf PF00755.15 CAR28029.1 - 6.5e-171 569.3 0.0 7.5e-171 569.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Tropomyosin_1 PF12718.2 CAR28030.1 - 9.9e-05 22.2 3.0 0.00015 21.6 2.1 1.3 1 0 0 1 1 1 1 Tropomyosin like TMF_TATA_bd PF12325.3 CAR28030.1 - 0.028 14.1 5.0 0.036 13.7 1.8 1.9 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.10 CAR28030.1 - 0.45 10.0 3.0 1.1 8.8 0.1 2.2 1 1 1 2 2 2 0 Septum formation initiator DER1 PF04511.10 CAR28031.1 - 7.1e-46 156.2 10.7 8.7e-46 155.9 7.4 1.1 1 0 0 1 1 1 1 Der1-like family Cg6151-P PF10233.4 CAR28031.1 - 0.0066 16.4 1.2 0.0066 16.4 0.8 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein CG6151-P Rhomboid PF01694.17 CAR28031.1 - 0.028 14.4 5.3 0.04 13.9 3.7 1.3 1 0 0 1 1 1 0 Rhomboid family Nop25 PF09805.4 CAR28032.1 - 1.1e-33 116.2 18.9 1.1e-33 116.2 13.1 1.6 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) YlqD PF11068.3 CAR28032.1 - 0.4 10.7 13.3 0.078 13.0 6.6 1.7 2 0 0 2 2 2 0 YlqD protein BTV_NS2 PF04514.7 CAR28032.1 - 3.2 6.5 14.7 4.8 5.9 10.2 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 EXS PF03124.9 CAR28033.1 - 1.6e-52 178.7 28.3 2e-52 178.3 19.6 1.0 1 0 0 1 1 1 1 EXS family Ribosomal_L2_C PF03947.13 CAR28034.1 - 3.7e-50 169.0 1.0 6.4e-50 168.2 0.7 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CAR28034.1 - 1.3e-26 92.3 0.0 1.3e-26 92.3 0.0 2.1 3 0 0 3 3 3 1 Ribosomal Proteins L2, RNA binding domain Peptidase_M28 PF04389.12 CAR28035.1 - 1e-26 93.7 0.1 1.9e-26 92.9 0.0 1.4 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 CAR28035.1 - 2.1e-06 27.3 0.0 2.8e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 ATP-synt_D PF01813.12 CAR28036.1 - 2.4e-65 219.7 3.4 3.5e-65 219.2 2.3 1.2 1 0 0 1 1 1 1 ATP synthase subunit D DUF972 PF06156.8 CAR28036.1 - 0.045 14.1 8.8 0.15 12.4 3.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF848 PF05852.6 CAR28036.1 - 1.2 8.9 9.5 3.9 7.3 5.0 2.4 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) HAUS6_N PF14661.1 CAR28036.1 - 1.9 7.7 7.7 1.5 8.1 2.1 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus RNase_H2-Ydr279 PF09468.5 CAR28036.1 - 2 7.5 7.1 2.5 7.2 4.9 1.3 1 1 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) APG6 PF04111.7 CAR28036.1 - 2.1 7.3 13.6 0.36 9.8 6.6 1.7 2 0 0 2 2 2 0 Autophagy protein Apg6 PBP_sp32 PF07222.7 CAR28036.1 - 2.1 7.4 7.2 3.2 6.8 5.0 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 TPR_11 PF13414.1 CAR28037.1 - 0.0076 15.8 0.7 16 5.2 0.1 3.9 3 0 0 3 3 3 1 TPR repeat TPR_14 PF13428.1 CAR28037.1 - 0.012 16.1 1.3 1.1e+02 3.8 0.0 6.1 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 CAR28037.1 - 0.015 15.9 0.5 2.4 8.9 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 CAR28037.1 - 0.027 14.4 0.1 0.45 10.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 CAR28037.1 - 0.089 13.1 2.7 0.26 11.6 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat PAH PF02671.16 CAR28037.1 - 0.2 11.3 2.7 20 4.9 0.0 4.0 4 0 0 4 4 4 0 Paired amphipathic helix repeat AFG1_ATPase PF03969.11 CAR28038.1 - 8.1e-75 251.8 0.0 4.7e-71 239.4 0.0 2.4 2 1 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 CAR28038.1 - 0.00021 21.3 1.2 0.051 13.5 0.0 3.1 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 CAR28038.1 - 0.0015 18.6 0.0 0.0034 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 CAR28038.1 - 0.0043 16.7 0.0 0.0072 16.0 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.1 CAR28038.1 - 0.023 14.6 0.7 0.11 12.4 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA PF00004.24 CAR28038.1 - 0.031 14.4 0.0 0.094 12.9 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 CAR28038.1 - 0.037 14.1 0.0 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 RNA helicase PIP5K PF01504.13 CAR28038.1 - 0.044 12.8 0.1 0.094 11.8 0.1 1.5 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Arch_ATPase PF01637.13 CAR28038.1 - 0.076 12.6 0.0 0.22 11.1 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase Mak10 PF04112.8 CAR28039.1 - 1.6e-41 141.3 0.0 4.1e-41 139.9 0.0 1.7 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Ribosomal_L11_N PF03946.9 CAR28040.1 - 1.5e-17 62.8 0.3 3.2e-17 61.7 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 CAR28040.1 - 6.2e-10 39.0 0.2 1.3e-09 38.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain IMS PF00817.15 CAR28041.1 - 6e-44 149.4 0.0 9.1e-44 148.8 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 CAR28041.1 - 8.5e-11 41.8 0.1 2.1e-10 40.5 0.1 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 CAR28041.1 - 0.043 13.8 0.0 0.21 11.7 0.0 2.2 2 0 0 2 2 2 0 IMS family HHH motif zf-C4H2 PF10146.4 CAR28042.1 - 0.065 13.2 0.0 0.56 10.1 0.0 2.7 1 0 0 1 1 1 0 Zinc finger-containing protein DUF912 PF06024.7 CAR28042.1 - 0.18 11.8 0.0 17 5.5 0.0 3.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TMEM223 PF14640.1 CAR28042.1 - 0.57 10.1 0.1 2.4 8.0 0.0 2.0 2 0 0 2 2 2 0 Transmembrane protein 223 Zn_clus PF00172.13 CAR28043.1 - 3.5e-08 33.2 10.2 6.5e-08 32.3 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RepA_N PF06970.6 CAR28043.1 - 0.031 14.0 0.0 0.073 12.8 0.0 1.6 1 0 0 1 1 1 0 Replication initiator protein A (RepA) N-terminus Dickkopf_N PF04706.7 CAR28043.1 - 2.5 8.3 9.2 13 6.0 0.8 3.0 3 0 0 3 3 3 0 Dickkopf N-terminal cysteine-rich region AMPKBI PF04739.10 CAR28045.1 - 3e-27 94.4 0.8 3.4e-26 91.0 0.0 2.8 3 0 0 3 3 3 1 5'-AMP-activated protein kinase beta subunit, interation domain Metaviral_G PF09595.5 CAR28045.1 - 0.65 9.6 17.6 0.027 14.1 5.9 2.4 2 0 0 2 2 2 0 Metaviral_G glycoprotein PAP1 PF08601.5 CAR28046.1 - 3.2e-48 165.1 59.2 1e-40 140.5 6.7 3.4 1 1 2 3 3 3 2 Transcription factor PAP1 bZIP_1 PF00170.16 CAR28046.1 - 2e-09 37.2 7.0 4.6e-09 36.0 4.8 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CAR28046.1 - 1.2e-06 28.2 8.1 3.1e-06 26.8 5.6 1.8 1 0 0 1 1 1 1 Basic region leucine zipper DUF972 PF06156.8 CAR28046.1 - 0.58 10.5 7.5 1.9 8.8 5.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF972) MscS_TM PF12794.2 CAR28046.1 - 3 6.3 3.2 4.8 5.6 2.2 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Sterol_MT_C PF08498.5 CAR28047.1 - 1.4e-28 98.5 1.0 2.2e-28 97.9 0.7 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 CAR28047.1 - 5.3e-21 74.9 0.0 9.6e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAR28047.1 - 2.5e-17 62.8 0.0 4e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAR28047.1 - 1.1e-14 54.5 0.0 1.7e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CAR28047.1 - 1.6e-12 47.0 0.3 2.3e-12 46.5 0.2 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 CAR28047.1 - 8.8e-12 45.5 0.0 2e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAR28047.1 - 6.5e-11 42.5 0.1 1.5e-10 41.3 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAR28047.1 - 2.4e-10 40.6 0.0 4.7e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CAR28047.1 - 2.4e-10 39.9 0.0 3.6e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 CAR28047.1 - 4.8e-08 33.0 0.0 1.5e-07 31.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 CAR28047.1 - 9.7e-07 28.4 0.4 2.2e-06 27.3 0.3 1.5 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 CAR28047.1 - 7.1e-05 22.0 0.0 0.00014 21.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 CAR28047.1 - 0.00042 19.8 0.0 0.00082 18.9 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.13 CAR28047.1 - 0.00072 19.1 0.0 0.0017 17.9 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 MTS PF05175.9 CAR28047.1 - 0.00093 18.6 0.1 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.11 CAR28047.1 - 0.0035 16.9 0.0 0.0059 16.2 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein RrnaAD PF00398.15 CAR28047.1 - 0.0047 15.9 0.0 0.0077 15.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.13 CAR28047.1 - 0.018 14.2 0.0 0.06 12.5 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase Methyltransf_32 PF13679.1 CAR28047.1 - 0.075 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Sugar_tr PF00083.19 CAR28048.1 - 3.9e-29 101.5 40.1 3e-19 68.9 9.8 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CAR28048.1 - 4.2e-18 65.1 67.0 1.2e-14 53.8 28.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Kinesin PF00225.18 CAR28049.1 - 1.2e-100 336.5 1.9 1.2e-100 336.5 1.3 1.4 2 0 0 2 2 2 1 Kinesin motor domain MSP1b PF03429.8 CAR28049.1 - 0.02 12.8 0.0 0.029 12.2 0.0 1.3 1 0 0 1 1 1 0 Major surface protein 1B DUF4606 PF15379.1 CAR28049.1 - 0.063 13.3 3.2 0.2 11.7 2.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4606) Transposase_1 PF01359.13 CAR28049.1 - 0.08 12.7 2.0 0.22 11.3 0.2 2.3 2 0 0 2 2 2 0 Transposase (partial DDE domain) Dynein_light PF01221.13 CAR28050.1 - 5.8e-35 119.1 0.1 6.6e-35 118.9 0.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.13 CAR28050.1 - 0.052 13.8 0.0 0.065 13.5 0.0 1.2 1 0 0 1 1 1 0 Ground-like domain PX PF00787.19 CAR28051.1 - 7.9e-15 54.6 0.2 3.4e-14 52.5 0.1 2.1 1 0 0 1 1 1 1 PX domain Katanin_con80 PF13925.1 CAR28051.1 - 1.3 8.7 9.1 1.3 8.7 1.6 2.5 2 0 0 2 2 2 0 con80 domain of Katanin PCI PF01399.22 CAR28052.1 - 1.5e-13 50.9 0.7 3.3e-13 49.8 0.0 2.0 2 0 0 2 2 2 1 PCI domain SLS PF14611.1 CAR28052.1 - 0.0024 17.3 0.9 0.0045 16.4 0.6 1.4 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator Spo0A_C PF08769.6 CAR28052.1 - 0.036 13.9 0.0 0.088 12.6 0.0 1.6 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal Abhydrolase_3 PF07859.8 CAR28053.1 - 1.2e-11 44.6 0.0 1.3e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CAR28053.1 - 3.5e-08 33.3 0.0 4.3e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CAR28053.1 - 6.2e-05 22.9 0.0 8.9e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 CAR28053.1 - 0.00043 20.5 0.0 0.00067 19.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.20 CAR28053.1 - 0.023 14.3 0.0 0.064 12.8 0.0 1.8 1 1 1 2 2 2 0 Lipase (class 3) DUF2305 PF10230.4 CAR28053.1 - 0.072 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF2974 PF11187.3 CAR28053.1 - 0.078 12.3 0.0 0.28 10.5 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.15 CAR28053.1 - 0.082 12.4 0.0 0.14 11.7 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold eIF3g PF12353.3 CAR28054.1 - 2.2e-44 150.4 2.6 3.1e-44 149.9 1.8 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 CAR28054.1 - 1.2e-10 40.8 0.0 2.1e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR28054.1 - 1.5e-06 28.1 0.0 2.6e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR28054.1 - 8.7e-05 22.3 0.0 0.00018 21.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L33 PF00471.15 CAR28055.1 - 0.00044 20.4 0.0 0.012 15.8 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein L33 Spt5-NGN PF03439.8 CAR28056.1 - 2e-20 72.3 0.0 4.2e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 CAR28056.1 - 3.3e-18 66.1 15.8 3.3e-18 66.1 11.0 4.4 2 1 2 4 4 4 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 CAR28056.1 - 6.6e-15 54.1 16.3 0.0028 17.2 0.1 4.8 4 0 0 4 4 4 4 KOW motif Rad33 PF08730.5 CAR28057.1 - 8e-37 126.3 4.0 2.3e-34 118.3 2.8 2.1 1 1 0 1 1 1 1 Rad33 EMP24_GP25L PF01105.19 CAR28058.1 - 2.3e-43 148.0 0.0 2.7e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.7 CAR28058.1 - 0.0093 14.1 0.2 0.011 13.9 0.2 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DUF3810 PF12725.2 CAR28058.1 - 0.032 13.1 0.0 0.71 8.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) M16C_assoc PF08367.6 CAR28059.1 - 5e-77 258.0 0.0 7.9e-77 257.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 CAR28059.1 - 6.1e-31 107.5 0.1 2.6e-18 66.3 0.0 3.0 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CAR28059.1 - 2.7e-07 30.4 0.0 9.8e-07 28.6 0.0 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) RRM_1 PF00076.17 CAR28060.1 - 1.5e-29 101.4 0.4 2.1e-17 62.4 0.2 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR28060.1 - 5.9e-17 61.4 0.0 1.2e-11 44.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR28060.1 - 1.2e-11 44.3 0.0 8.2e-11 41.5 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 CAR28060.1 - 0.062 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 RNA binding domain Limkain-b1 PF11608.3 CAR28060.1 - 0.084 12.6 0.0 16 5.3 0.0 2.3 2 0 0 2 2 2 0 Limkain b1 UBX PF00789.15 CAR28061.1 - 2.4e-11 43.5 0.0 4.4e-10 39.4 0.0 2.7 2 1 0 2 2 2 1 UBX domain UBA_4 PF14555.1 CAR28061.1 - 5.3e-10 38.6 0.0 3.1e-09 36.2 0.0 2.2 2 0 0 2 2 2 1 UBA-like domain Methyltransf_11 PF08241.7 CAR28062.1 - 1.9e-12 47.4 0.0 4.3e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAR28062.1 - 1.3e-06 28.8 0.2 5.7e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAR28062.1 - 3e-06 26.9 0.0 4.8e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAR28062.1 - 7e-06 25.8 0.1 3.1e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAR28062.1 - 3.3e-05 24.1 0.0 8.5e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR28062.1 - 0.00052 20.5 0.2 0.0012 19.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PIG-S PF10510.4 CAR28063.1 - 3.6e-137 458.1 1.6 4.2e-137 457.9 1.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein TAFII28 PF04719.9 CAR28064.1 - 1.6e-26 91.9 2.1 7.1e-25 86.6 1.2 2.3 2 0 0 2 2 2 2 hTAFII28-like protein conserved region DUF2986 PF11661.3 CAR28064.1 - 0.38 11.0 3.4 0.81 10.0 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2986) LCM PF04072.9 CAR28065.1 - 1.6e-18 66.9 0.0 2.2e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Methyltransf_18 PF12847.2 CAR28065.1 - 0.029 14.9 0.0 0.057 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Metallophos PF00149.23 CAR28066.1 - 2.4e-39 134.8 0.2 4.1e-39 134.0 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PIG-P PF08510.7 CAR28067.1 - 2.8e-31 107.7 2.5 3.4e-31 107.5 1.7 1.1 1 0 0 1 1 1 1 PIG-P MFS_2 PF13347.1 CAR28067.1 - 0.0027 16.1 0.3 0.0032 15.9 0.2 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein MGC-24 PF05283.6 CAR28068.1 - 3.8 7.2 15.2 8.4 6.1 10.5 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) EamA PF00892.15 CAR28069.1 - 7.2e-10 38.9 21.1 4.2e-06 26.8 0.5 3.6 3 1 1 4 4 4 2 EamA-like transporter family TPT PF03151.11 CAR28069.1 - 5e-09 35.9 23.0 1.7e-06 27.7 6.5 3.1 3 0 0 3 3 3 2 Triose-phosphate Transporter family DUF914 PF06027.7 CAR28069.1 - 7.4e-06 25.0 10.2 7.4e-06 25.0 7.1 1.6 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 CAR28069.1 - 0.0001 21.3 16.3 0.0002 20.3 11.3 1.3 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 CAR28069.1 - 0.0088 16.2 4.0 0.0088 16.2 2.8 3.5 3 1 1 4 4 4 1 Multidrug resistance efflux transporter DUF3094 PF11293.3 CAR28069.1 - 5.8 6.4 9.3 1.6 8.2 3.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) OST3_OST6 PF04756.8 CAR28070.1 - 2.4e-23 82.4 7.1 3.2e-23 82.0 4.9 1.2 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 CAR28070.1 - 0.041 13.5 0.0 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin LRS4 PF10422.4 CAR28071.1 - 9.6e-26 90.6 9.9 1.3e-25 90.2 5.7 1.9 1 1 0 1 1 1 1 Monopolin complex subunit LRS4 Serglycin PF04360.7 CAR28071.1 - 8e-05 22.4 1.0 0.00014 21.6 0.7 1.5 1 0 0 1 1 1 1 Serglycin FlxA PF14282.1 CAR28071.1 - 0.00064 19.6 7.6 0.00064 19.6 5.3 2.3 2 0 0 2 2 2 1 FlxA-like protein DUF3246 PF11596.3 CAR28071.1 - 0.011 15.0 5.3 0.024 13.9 1.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) TPR_MLP1_2 PF07926.7 CAR28071.1 - 0.027 14.2 11.5 0.079 12.7 6.2 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Herpes_PAP PF03325.8 CAR28071.1 - 0.047 13.2 1.5 0.069 12.6 1.0 1.3 1 0 0 1 1 1 0 Herpesvirus polymerase accessory protein Dsl1_C PF11989.3 CAR28071.1 - 0.081 12.0 1.1 0.13 11.4 0.8 1.3 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 C terminal Enkurin PF13864.1 CAR28071.1 - 5.4 7.2 10.8 0.37 11.0 3.7 1.8 2 0 0 2 2 2 0 Calmodulin-binding CCDC-167 PF15188.1 CAR28071.1 - 6.3 6.8 8.4 21 5.1 5.8 1.9 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 SEO_C PF14577.1 CAR28072.1 - 0.064 12.6 0.2 0.21 10.9 0.1 1.8 2 0 0 2 2 2 0 Sieve element occlusion C-terminus UDG PF03167.14 CAR28073.1 - 8.7e-26 90.2 0.0 1.7e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Host_attach PF10116.4 CAR28073.1 - 0.27 11.4 1.2 0.64 10.2 0.1 2.0 2 0 0 2 2 2 0 Protein required for attachment to host cells DOT1 PF08123.8 CAR28074.1 - 9.4e-87 289.6 0.0 1.4e-86 289.0 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Pribosyltran PF00156.22 CAR28075.1 - 1.1e-17 63.8 0.0 1.6e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CAR28075.1 - 0.0029 16.8 0.0 0.004 16.3 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase MoCF_biosynth PF00994.19 CAR28075.1 - 0.014 14.7 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Probable molybdopterin binding domain Nse5 PF08691.5 CAR28076.1 - 1.3e-164 548.5 12.3 1.5e-164 548.3 8.5 1.0 1 0 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 Med13_C PF06333.7 CAR28077.1 - 5.6e-85 285.4 4.8 4.9e-56 190.0 0.3 2.7 2 1 1 3 3 3 2 Mediator complex subunit 13 C-terminal GSHPx PF00255.14 CAR28078.1 - 2.7e-47 158.6 0.3 3.3e-47 158.3 0.2 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 CAR28078.1 - 1.6e-05 24.5 0.0 5.2e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CAR28078.1 - 1.9e-05 24.2 0.1 5.8e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 Redoxin Sugar_tr PF00083.19 CAR28079.1 - 3.3e-158 526.9 25.3 3.9e-158 526.7 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR28079.1 - 2.3e-40 138.3 38.0 1e-36 126.4 13.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cytochrom_B_N PF00033.14 CAR28079.1 - 0.043 13.1 8.6 0.035 13.4 1.9 3.4 3 1 0 3 3 3 0 Cytochrome b(N-terminal)/b6/petB Ni_hydr_CYTB PF01292.15 CAR28079.1 - 0.054 12.8 3.3 0.52 9.6 0.8 3.2 3 1 1 4 4 4 0 Prokaryotic cytochrome b561 OPT PF03169.10 CAR28080.1 - 2.2e-158 528.5 42.5 2.5e-158 528.3 29.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF676 PF05057.9 CAR28081.1 - 6.1e-49 166.2 0.0 9.7e-49 165.6 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 CAR28081.1 - 0.00077 19.0 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF915 PF06028.6 CAR28081.1 - 0.0013 17.8 0.0 0.0022 17.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_6 PF12697.2 CAR28081.1 - 0.065 13.1 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CAR28081.1 - 0.081 12.6 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAR28081.1 - 0.13 11.8 0.1 2.8 7.4 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold FAD-oxidase_C PF02913.14 CAR28082.1 - 4e-46 157.3 0.0 5.7e-46 156.8 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CAR28082.1 - 1.3e-32 112.1 0.1 3.2e-32 110.9 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain DUF4356 PF14266.1 CAR28082.1 - 0.0056 15.1 0.1 0.0086 14.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4356) ECM11 PF15463.1 CAR28083.1 - 4.6e-27 94.9 1.5 4.6e-27 94.9 1.0 2.5 1 1 2 3 3 3 1 Extracellular mutant protein 11 BLOC1_2 PF10046.4 CAR28083.1 - 0.032 14.3 1.4 0.23 11.6 0.2 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Nnf1 PF03980.9 CAR28083.1 - 0.046 13.7 0.6 0.046 13.7 0.4 2.0 2 0 0 2 2 2 0 Nnf1 Tom22 PF04281.8 CAR28083.1 - 0.79 9.2 5.6 0.17 11.4 0.6 2.1 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Ribosomal_S17e PF00833.13 CAR28084.1 - 1.5e-54 182.9 0.2 1.8e-54 182.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal S17 ZZ PF00569.12 CAR28085.1 - 3.6e-14 52.0 7.8 6.7e-14 51.1 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.12 CAR28085.1 - 5.1e-12 45.7 0.1 6.9e-11 42.1 0.0 2.4 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.26 CAR28085.1 - 1.8e-06 27.8 0.0 3.5e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CAR28085.1 - 0.0097 15.9 0.0 0.028 14.5 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Enterotoxin_b PF01376.13 CAR28085.1 - 0.077 12.8 0.0 2.1 8.2 0.0 2.4 2 0 0 2 2 2 0 Heat-labile enterotoxin beta chain Baculo_IE-1 PF05290.6 CAR28085.1 - 1.8 8.2 5.6 3.6 7.3 3.9 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) U3_assoc_6 PF08640.6 CAR28086.1 - 9.5e-33 111.8 4.0 5.3e-31 106.2 0.4 2.7 2 0 0 2 2 2 2 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.5 CAR28086.1 - 3.9e-05 22.6 7.4 0.00047 19.1 2.0 2.5 1 1 1 2 2 2 2 NRDE-2, necessary for RNA interference Suf PF05843.9 CAR28086.1 - 0.003 17.3 9.7 0.013 15.2 4.1 3.6 3 1 0 3 3 3 1 Suppressor of forked protein (Suf) DUF2250 PF10007.4 CAR28086.1 - 0.017 15.0 0.1 0.94 9.4 0.0 2.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) TPR_14 PF13428.1 CAR28086.1 - 0.022 15.3 0.0 0.3 11.8 0.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 CAR28086.1 - 0.12 12.0 0.1 0.56 9.9 0.0 2.3 2 0 0 2 2 2 0 TPR repeat HAT PF02184.11 CAR28086.1 - 0.3 10.8 2.2 0.52 10.0 0.2 2.4 2 0 0 2 2 2 0 HAT (Half-A-TPR) repeat Ribosomal_L4 PF00573.17 CAR28087.1 - 3.4e-49 166.8 0.0 4.1e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_S13 PF00416.17 CAR28088.1 - 5.5e-42 142.5 1.6 6.4e-42 142.3 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 CAR28088.1 - 0.00089 17.9 0.0 0.00095 17.8 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.1 CAR28088.1 - 0.097 12.7 0.2 0.38 10.8 0.1 2.0 2 1 0 2 2 2 0 Helix-hairpin-helix motif PP28 PF10252.4 CAR28088.1 - 0.1 12.6 0.5 0.1 12.6 0.4 1.7 2 0 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 Homeobox PF00046.24 CAR28089.1 - 5.6e-18 64.3 7.0 3.9e-17 61.6 4.2 2.3 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 CAR28089.1 - 0.014 15.1 5.3 0.016 14.8 0.2 3.0 3 0 0 3 3 3 0 Homeobox KN domain Metallophos PF00149.23 CAR28090.1 - 6.4e-11 42.0 1.8 1.3e-09 37.8 0.7 2.1 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase AhpC-TSA PF00578.16 CAR28091.1 - 5.6e-37 126.1 0.0 1.1e-36 125.2 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 CAR28091.1 - 2.2e-21 75.9 0.0 3.5e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CAR28091.1 - 1.4e-08 34.2 0.1 2.7e-08 33.2 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin ubiquitin PF00240.18 CAR28092.1 - 0.0015 17.9 0.0 0.0045 16.3 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family Hex_IIIa PF02455.11 CAR28092.1 - 0.0044 15.7 1.2 0.0044 15.7 0.8 1.6 2 0 0 2 2 2 1 Hexon-associated protein (IIIa) Pex2_Pex12 PF04757.9 CAR28092.1 - 0.0059 16.0 0.1 0.12 11.7 0.0 2.4 2 0 0 2 2 2 1 Pex2 / Pex12 amino terminal region Rad60-SLD_2 PF13881.1 CAR28092.1 - 0.015 15.2 0.0 0.015 15.2 0.0 2.5 3 0 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.3 CAR28092.1 - 0.023 14.3 0.1 0.1 12.2 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like WHG PF13305.1 CAR28092.1 - 0.14 12.7 0.8 3.9 8.1 0.0 2.9 2 0 0 2 2 2 0 WHG domain HIG_1_N PF04588.8 CAR28093.1 - 1.2e-20 72.9 2.1 1.6e-20 72.5 1.4 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region CD20 PF04103.10 CAR28093.1 - 0.009 15.9 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 1 CD20-like family DUF3995 PF13160.1 CAR28093.1 - 0.072 13.1 0.0 0.092 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3995) DUF4407 PF14362.1 CAR28093.1 - 0.081 11.8 5.4 0.12 11.2 3.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3287 PF11690.3 CAR28093.1 - 0.34 10.9 5.7 0.63 10.1 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) DUF342 PF03961.8 CAR28093.1 - 0.34 9.2 3.6 0.36 9.1 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Spc7 PF08317.6 CAR28093.1 - 1.9 7.0 14.1 9.6 4.7 6.6 2.8 3 0 0 3 3 3 0 Spc7 kinetochore protein IncA PF04156.9 CAR28093.1 - 5.7 6.4 16.3 0.13 11.8 7.0 1.5 2 0 0 2 2 2 0 IncA protein Guanylate_kin PF00625.16 CAR28094.1 - 9.7e-68 227.2 0.0 1.1e-67 227.0 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.1 CAR28094.1 - 2.4e-06 27.4 0.0 1.1e-05 25.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CAR28094.1 - 2.2e-05 24.5 0.0 4.4e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 CAR28094.1 - 0.0001 22.6 0.0 0.00029 21.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CAR28094.1 - 0.00015 21.8 0.0 0.0017 18.5 0.0 2.1 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.1 CAR28094.1 - 0.0002 21.4 0.0 0.00051 20.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CAR28094.1 - 0.00022 22.0 0.0 0.00033 21.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CAR28094.1 - 0.0016 18.4 0.0 0.0032 17.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 CAR28094.1 - 0.0016 17.6 0.0 0.0027 16.8 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 CAR28094.1 - 0.0025 17.7 0.0 0.0059 16.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 CAR28094.1 - 0.0048 17.0 0.1 0.0078 16.4 0.1 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 CAR28094.1 - 0.0056 16.9 0.0 0.013 15.8 0.0 1.5 1 1 0 1 1 1 1 ABC transporter T2SE PF00437.15 CAR28094.1 - 0.0068 15.3 0.0 0.017 14.0 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein MMR_HSR1 PF01926.18 CAR28094.1 - 0.009 15.9 0.0 0.011 15.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 CAR28094.1 - 0.01 15.3 1.2 0.031 13.8 0.1 2.1 2 1 0 2 2 2 0 P-loop containing region of AAA domain NACHT PF05729.7 CAR28094.1 - 0.021 14.4 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Miro PF08477.8 CAR28094.1 - 0.032 14.7 0.0 0.052 14.0 0.0 1.5 1 1 0 1 1 1 0 Miro-like protein AAA_10 PF12846.2 CAR28094.1 - 0.032 13.6 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_24 PF13479.1 CAR28094.1 - 0.041 13.4 0.0 0.069 12.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CAR28094.1 - 0.045 13.5 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 CAR28094.1 - 0.052 13.2 0.1 0.32 10.7 0.0 2.2 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 CAR28094.1 - 0.055 13.1 0.0 0.063 12.9 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase AAA_25 PF13481.1 CAR28094.1 - 0.059 12.7 0.1 0.29 10.4 0.0 2.0 2 1 1 3 3 3 0 AAA domain NTPase_1 PF03266.10 CAR28094.1 - 0.079 12.6 0.1 0.13 11.9 0.1 1.6 1 1 0 1 1 1 0 NTPase MobB PF03205.9 CAR28094.1 - 0.09 12.4 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 CAR28094.1 - 0.093 13.0 1.0 0.14 12.4 0.7 1.7 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 CAR28094.1 - 0.1 11.5 0.0 0.16 10.8 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.14 CAR28094.1 - 0.12 11.8 0.0 0.54 9.6 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Na_H_Exchanger PF00999.16 CAR28095.1 - 4.1e-62 209.8 39.1 5.3e-62 209.5 27.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Myc_target_1 PF15179.1 CAR28095.1 - 0.068 12.7 3.7 0.24 10.9 0.9 2.4 2 0 0 2 2 2 0 Myc target protein 1 Ndc1_Nup PF09531.5 CAR28096.1 - 4.9e-120 401.7 29.6 2.4e-119 399.5 20.5 1.8 1 1 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Rad52_Rad22 PF04098.10 CAR28097.1 - 1.9e-56 190.0 0.0 2.7e-56 189.5 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein HECT PF00632.20 CAR28098.1 - 5.3e-91 305.0 0.1 5.3e-91 305.0 0.1 2.7 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 CAR28098.1 - 2.6e-79 266.9 0.4 1e-78 264.9 0.3 2.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) DUF913 PF06025.7 CAR28098.1 - 2.1e-45 155.1 0.2 8.7e-45 153.0 0.0 2.2 2 0 0 2 2 2 1 Domain of Unknown Function (DUF913) DUF4414 PF14377.1 CAR28098.1 - 1.6e-16 60.1 3.0 6.7e-16 58.1 2.1 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4414) MSC PF09402.5 CAR28099.1 - 2.6e-103 345.2 1.7 6e-103 344.0 1.2 1.6 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 CAR28099.1 - 7.4e-18 63.8 0.1 2e-17 62.4 0.1 1.8 1 0 0 1 1 1 1 HeH/LEM domain LEAP-2 PF07359.6 CAR28099.1 - 0.26 10.9 3.8 12 5.6 0.0 4.0 4 0 0 4 4 4 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) A_deaminase PF00962.17 CAR28100.1 - 4.2e-117 390.7 0.2 5.5e-117 390.3 0.1 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase zf-DHHC PF01529.15 CAR28101.1 - 2e-25 89.2 7.2 2e-25 89.2 5.0 1.9 1 1 1 2 2 2 1 DHHC palmitoyltransferase MAT1 PF06391.8 CAR28102.1 - 4.3e-59 199.4 23.3 5.3e-59 199.1 16.2 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_2 PF13923.1 CAR28102.1 - 0.0013 18.7 4.8 0.0028 17.6 3.4 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CAR28102.1 - 0.0013 18.3 2.7 0.0037 16.9 1.9 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CAR28102.1 - 0.018 14.7 5.0 0.032 13.9 3.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAR28102.1 - 0.018 14.7 5.5 0.037 13.7 3.8 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 CAR28102.1 - 0.028 14.2 5.9 0.054 13.3 4.1 1.5 1 0 0 1 1 1 0 Ring finger domain DNA_topoisoIV PF00521.15 CAR28102.1 - 0.05 12.4 5.6 0.059 12.2 3.9 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Spectrin PF00435.16 CAR28102.1 - 0.3 11.3 11.1 1 9.6 6.5 2.4 1 1 1 2 2 2 0 Spectrin repeat zf-RING_UBOX PF13445.1 CAR28102.1 - 0.3 10.8 4.0 0.78 9.5 2.8 1.8 1 0 0 1 1 1 0 RING-type zinc-finger APG6 PF04111.7 CAR28102.1 - 0.63 9.0 14.3 0.94 8.4 9.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Mitovir_RNA_pol PF05919.6 CAR28102.1 - 0.87 8.4 5.3 1.1 8.1 3.6 1.1 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase zf-RING_4 PF14570.1 CAR28102.1 - 1 9.0 7.9 2.9 7.5 5.5 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Exonuc_VII_L PF02601.10 CAR28102.1 - 1.8 7.7 9.2 2.5 7.2 6.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CGI-121 PF08617.5 CAR28103.1 - 4.5e-36 123.9 2.2 5.5e-36 123.6 1.5 1.1 1 0 0 1 1 1 1 Kinase binding protein CGI-121 DUF3568 PF12092.3 CAR28103.1 - 0.0079 15.9 0.1 4.1 7.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3568) MRP-L28 PF09812.4 CAR28105.1 - 7.4e-36 123.3 3.9 8.8e-36 123.0 2.7 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Pol_alpha_B_N PF08418.5 CAR28105.1 - 0.0028 17.2 0.8 0.003 17.1 0.5 1.0 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DUF4093 PF13331.1 CAR28105.1 - 0.081 13.1 0.2 0.13 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4093) FYRC PF05965.9 CAR28105.1 - 0.1 12.4 0.1 0.25 11.1 0.0 1.7 2 0 0 2 2 2 0 F/Y rich C-terminus TPT PF03151.11 CAR28106.1 - 3e-38 130.8 1.4 3e-38 130.8 0.9 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 CAR28106.1 - 4.7e-11 42.1 12.3 7.4e-10 38.2 8.6 2.0 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 CAR28106.1 - 1.8e-05 24.7 21.3 9.3e-05 22.4 3.7 3.0 2 2 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 CAR28106.1 - 3.2e-05 24.0 0.9 3.2e-05 24.0 0.6 3.1 3 1 0 3 3 3 1 Multidrug resistance efflux transporter Ni_hydr_CYTB PF01292.15 CAR28106.1 - 0.00019 20.8 4.6 0.5 9.7 0.0 3.2 2 1 1 3 3 3 3 Prokaryotic cytochrome b561 UPF0546 PF10639.4 CAR28106.1 - 0.015 15.1 5.1 0.86 9.4 0.1 3.0 3 0 0 3 3 3 0 Uncharacterised protein family UPF0546 DUF4131 PF13567.1 CAR28106.1 - 0.63 9.4 5.0 3.1 7.1 0.8 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) DUF485 PF04341.7 CAR28106.1 - 6.3 6.5 13.0 2 8.1 0.1 3.9 4 1 0 4 4 4 0 Protein of unknown function, DUF485 zf-C2H2 PF00096.21 CAR28107.1 - 3.1e-06 27.1 11.4 0.00081 19.5 1.8 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CAR28107.1 - 2e-05 24.6 10.7 0.011 16.0 0.7 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CAR28107.1 - 0.013 15.7 12.3 0.085 13.1 0.6 3.9 3 0 0 3 3 3 0 Zinc-finger double domain zf-BED PF02892.10 CAR28107.1 - 0.11 12.2 4.5 0.15 11.8 0.2 3.0 3 0 0 3 3 3 0 BED zinc finger zf-C2H2_6 PF13912.1 CAR28107.1 - 0.12 12.3 2.8 0.5 10.3 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger HNH PF01844.18 CAR28107.1 - 0.77 9.6 4.1 15 5.5 0.4 2.8 2 0 0 2 2 2 0 HNH endonuclease DUF3020 PF11223.3 CAR28108.1 - 3.2e-12 46.6 11.5 3.2e-12 46.6 7.9 9.3 9 1 0 9 9 9 1 Protein of unknown function (DUF3020) p450 PF00067.17 CAR28109.1 - 2.2e-102 342.9 0.0 2.5e-102 342.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 CAR28110.1 - 1e-06 28.5 11.4 2.1e-06 27.4 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 CAR28110.1 - 1.2e-06 27.6 0.1 3.8e-06 25.9 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR28111.1 - 2.4e-09 36.9 8.1 7.7e-09 35.3 5.6 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Na_H_Exchanger PF00999.16 CAR28112.1 - 2.4e-82 276.4 19.9 2.9e-82 276.2 13.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Nha1_C PF08619.5 CAR28112.1 - 5.7e-63 213.6 10.5 7.5e-63 213.3 7.3 1.1 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus DcpS PF05652.7 CAR28113.1 - 7e-39 132.6 0.0 1e-38 132.0 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.3 CAR28113.1 - 2.4e-32 111.6 0.0 9.3e-32 109.6 0.0 1.9 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding DUF4187 PF13821.1 CAR28114.1 - 5.4e-14 51.5 3.9 1.4e-13 50.2 2.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 CAR28114.1 - 3.9e-05 23.3 0.1 8.4e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.3 CAR28114.1 - 0.015 15.4 0.9 0.028 14.5 0.6 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Med4 PF10018.4 CAR28115.1 - 1.3e-40 138.7 0.7 1.3e-40 138.7 0.5 1.6 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 Baculo_PEP_C PF04513.7 CAR28115.1 - 0.018 14.8 0.1 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 CAR28115.1 - 0.14 12.4 0.7 1.2 9.4 0.5 2.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein TBPIP PF07106.8 CAR28115.1 - 0.15 11.6 6.4 0.3 10.6 2.3 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) MBOAT PF03062.14 CAR28116.1 - 1.6e-56 191.7 15.7 1.6e-56 191.7 10.9 2.1 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Ferrochelatase PF00762.14 CAR28117.1 - 5.7e-89 298.1 0.0 6.6e-89 297.9 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Cnd1 PF12717.2 CAR28118.1 - 7.8e-52 175.7 9.7 2.9e-50 170.6 0.1 3.9 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 CAR28118.1 - 2.5e-48 163.9 6.1 2.5e-48 163.9 1.4 2.5 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 CAR28118.1 - 3.8e-10 39.9 0.0 0.0029 17.8 0.0 4.5 3 1 2 5 5 5 4 HEAT repeats HEAT PF02985.17 CAR28118.1 - 1.8e-09 36.9 1.6 0.3 11.2 0.0 5.8 5 0 0 5 5 5 4 HEAT repeat HEAT_EZ PF13513.1 CAR28118.1 - 3.9e-06 27.1 0.2 0.37 11.3 0.0 5.2 4 0 0 4 4 4 1 HEAT-like repeat CBM_21 PF03370.8 CAR28119.1 - 2.2e-27 95.2 4.6 6.3e-27 93.7 3.2 1.8 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit CBM_25 PF03423.8 CAR28119.1 - 0.11 12.6 2.7 4.5 7.4 0.9 2.9 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) MCM PF00493.18 CAR28120.1 - 3.5e-141 469.7 0.1 4.9e-141 469.3 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CAR28120.1 - 4.7e-21 75.5 0.3 1.6e-20 73.8 0.2 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 CAR28120.1 - 2.4e-06 26.8 0.0 0.00058 19.0 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CAR28120.1 - 1.6e-05 24.6 0.0 5.8e-05 22.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CAR28120.1 - 0.0021 17.6 0.0 0.0086 15.6 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CAR28120.1 - 0.039 13.4 0.0 1.2 8.5 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF1822 PF08852.6 CAR28120.1 - 0.049 12.4 0.5 3.4 6.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1822) Imm19 PF15567.1 CAR28120.1 - 0.16 11.9 0.0 0.47 10.4 0.0 1.7 1 0 0 1 1 1 0 Immunity protein 19 LSM PF01423.17 CAR28121.1 - 1.2e-17 63.2 1.3 1.5e-17 62.9 0.9 1.1 1 0 0 1 1 1 1 LSM domain Leu_zip PF15294.1 CAR28121.1 - 0.11 11.5 0.3 0.13 11.3 0.2 1.1 1 0 0 1 1 1 0 Leucine zipper DEAD PF00270.24 CAR28122.1 - 2.8e-40 137.5 1.8 5.8e-40 136.5 1.3 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR28122.1 - 1.3e-22 79.4 0.1 6.6e-11 41.9 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 CAR28122.1 - 3.2e-08 33.6 0.9 1e-06 28.7 0.1 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DnaI_N PF07319.6 CAR28122.1 - 0.3 11.3 6.5 1.1 9.5 0.1 3.5 4 0 0 4 4 4 0 Primosomal protein DnaI N-terminus CPSF73-100_C PF11718.3 CAR28123.1 - 1.7e-60 204.0 7.1 2.8e-60 203.3 4.9 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 CAR28123.1 - 4.8e-32 110.5 0.0 3.8e-31 107.6 0.0 2.3 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 CAR28123.1 - 1.5e-15 57.3 0.5 2.5e-15 56.6 0.3 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CAR28123.1 - 7.2e-13 48.5 0.5 5e-12 45.7 0.2 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.7 CAR28123.1 - 1.3e-10 40.9 0.0 2.6e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 CAR28123.1 - 9.3e-06 25.4 0.1 3e-05 23.8 0.1 1.9 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Fungal_trans PF04082.13 CAR28124.1 - 9.8e-18 63.9 1.5 2.4e-17 62.6 1.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR28124.1 - 1.2e-05 25.1 12.6 1.2e-05 25.1 8.8 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ECH PF00378.15 CAR28125.1 - 1.2e-27 96.6 0.0 1.5e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family RF-1 PF00472.15 CAR28126.1 - 1.3e-19 70.0 8.4 2.4e-19 69.1 5.8 1.5 1 1 0 1 1 1 1 RF-1 domain Peptidase_S49_N PF08496.5 CAR28126.1 - 2.2 8.0 8.4 2.9 7.6 5.8 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1640 PF07798.6 CAR28127.1 - 2.1e-06 27.9 6.2 2.1e-06 27.9 4.3 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) GRDA PF04723.9 CAR28127.1 - 0.079 12.6 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Glycine reductase complex selenoprotein A RRF_GI PF12614.3 CAR28127.1 - 0.088 12.6 1.7 0.13 12.0 0.4 1.8 2 0 0 2 2 2 0 Ribosome recycling factor ECH PF00378.15 CAR28128.1 - 4e-14 52.3 0.0 5.1e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Methyltransf_16 PF10294.4 CAR28129.1 - 2.2e-16 59.7 0.0 2.9e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 CAR28129.1 - 7.9e-05 22.4 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR28129.1 - 0.00033 21.2 0.0 0.00051 20.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAR28129.1 - 0.011 16.1 0.0 0.021 15.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CBM_19 PF03427.8 CAR28130.1 - 2.6e-05 23.8 11.0 2.6e-05 23.8 7.6 6.1 2 1 4 6 6 6 1 Carbohydrate binding domain (family 19) WH1 PF00568.18 CAR28131.1 - 4.7e-32 110.0 0.0 6.4e-32 109.5 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 CAR28131.1 - 0.00042 19.8 0.8 0.00089 18.7 0.6 1.6 1 0 0 1 1 1 1 WH2 motif GCIP PF13324.1 CAR28132.1 - 2.9e-13 49.6 0.3 4.1e-13 49.1 0.2 1.3 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting Syntaxin-6_N PF09177.6 CAR28132.1 - 0.16 12.4 9.5 4.3 7.8 0.3 4.3 3 3 0 3 3 3 0 Syntaxin 6, N-terminal Mt_ATP-synt_B PF05405.9 CAR28132.1 - 0.77 9.1 4.2 8.8 5.7 0.4 2.3 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Ribosomal_S30 PF04758.9 CAR28133.1 - 1.8e-28 98.0 5.4 2.1e-28 97.8 3.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Aminotran_5 PF00266.14 CAR28134.1 - 8.9e-35 120.1 0.0 1.2e-34 119.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Hus1 PF04005.7 CAR28135.1 - 1e-25 90.2 0.1 1.1e-24 86.9 0.1 2.0 1 1 0 1 1 1 1 Hus1-like protein GTP_EFTU PF00009.22 CAR28136.1 - 3.4e-48 163.5 0.0 5.4e-48 162.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 CAR28136.1 - 2.5e-38 130.2 7.8 2.5e-38 130.2 5.4 1.7 2 0 0 2 2 2 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 CAR28136.1 - 1.6e-17 63.1 0.0 2.9e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CAR28136.1 - 1.6e-06 28.1 1.6 4.9e-06 26.5 0.9 2.0 1 1 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CAR28136.1 - 3.8e-05 23.6 0.0 0.00011 22.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 CAR28136.1 - 0.0012 18.2 0.0 0.0032 16.8 0.0 1.6 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CAR28136.1 - 0.0044 16.2 0.0 0.011 14.9 0.0 1.7 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit EFG_II PF14492.1 CAR28136.1 - 0.0096 15.7 0.0 0.029 14.2 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II NAD_binding_10 PF13460.1 CAR28137.1 - 9.6e-12 45.2 0.0 7e-08 32.6 0.0 2.2 2 0 0 2 2 2 2 NADH(P)-binding Epimerase PF01370.16 CAR28137.1 - 2.4e-05 23.9 0.0 4.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CAR28137.1 - 4.3e-05 22.3 0.0 0.00015 20.5 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CAR28137.1 - 0.0092 14.9 0.0 0.36 9.6 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 CAR28137.1 - 0.022 14.6 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 CAR28137.1 - 0.076 11.8 0.0 0.17 10.7 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain IF-2B PF01008.12 CAR28138.1 - 1.6e-85 286.5 0.5 4.4e-85 285.0 0.3 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family ABC_sub_bind PF04392.7 CAR28138.1 - 0.0091 14.9 0.0 0.0091 14.9 0.0 1.6 2 0 0 2 2 2 1 ABC transporter substrate binding protein Di19_C PF14571.1 CAR28138.1 - 0.024 14.9 1.2 0.051 13.8 0.9 1.5 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal DUF1804 PF08822.6 CAR28138.1 - 0.054 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) Herpes_LP PF03363.8 CAR28138.1 - 0.33 10.5 2.1 0.6 9.6 1.5 1.4 1 0 0 1 1 1 0 Herpesvirus leader protein 7TM_GPCR_Srx PF10328.4 CAR28138.1 - 1.3 8.0 3.8 1.9 7.4 2.6 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx TPR_11 PF13414.1 CAR28139.1 - 0.00081 18.9 0.4 1.2 8.8 0.0 3.0 2 1 0 3 3 3 2 TPR repeat TPR_19 PF14559.1 CAR28139.1 - 0.0013 19.0 1.1 0.0037 17.5 0.0 2.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 CAR28139.1 - 0.003 17.0 0.1 0.55 9.9 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 CAR28139.1 - 0.0078 16.0 0.0 3.1 7.9 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CAR28139.1 - 0.078 13.6 0.6 0.93 10.3 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CAR28139.1 - 0.56 10.1 2.4 11 5.9 0.0 3.2 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Ras PF00071.17 CAR28140.1 - 7.8e-51 171.6 0.0 9.5e-51 171.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR28140.1 - 3.1e-17 63.1 0.0 6.6e-17 62.1 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CAR28140.1 - 1.4e-11 43.9 0.0 2e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 CAR28140.1 - 0.00061 19.9 0.2 0.0054 16.8 0.1 2.2 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 CAR28140.1 - 0.00068 18.8 0.0 0.00095 18.3 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CAR28140.1 - 0.015 14.5 0.0 0.025 13.8 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit KaiC PF06745.8 CAR28140.1 - 0.019 14.0 0.2 0.028 13.5 0.1 1.2 1 0 0 1 1 1 0 KaiC Pox_A32 PF04665.7 CAR28140.1 - 0.025 13.9 0.1 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_22 PF13401.1 CAR28140.1 - 0.051 13.7 0.2 0.16 12.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.15 CAR28140.1 - 0.054 12.1 3.3 1.1 7.8 0.1 2.8 2 1 1 3 3 3 0 G-protein alpha subunit AAA_33 PF13671.1 CAR28140.1 - 0.07 13.0 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CAR28140.1 - 0.13 11.9 0.1 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ADIP PF11559.3 CAR28141.1 - 2.9e-06 27.2 1.9 2.9e-06 27.2 1.3 2.8 2 1 0 3 3 3 1 Afadin- and alpha -actinin-Binding Cep57_MT_bd PF06657.8 CAR28141.1 - 0.0047 16.8 6.5 0.15 12.0 0.2 3.2 3 0 0 3 3 3 2 Centrosome microtubule-binding domain of Cep57 FliS PF02561.9 CAR28141.1 - 0.0058 16.4 6.4 0.03 14.1 0.0 3.2 3 0 0 3 3 3 1 Flagellar protein FliS G-gamma PF00631.17 CAR28141.1 - 0.014 15.1 1.1 0.57 9.9 0.0 2.6 2 0 0 2 2 2 0 GGL domain DUF16 PF01519.11 CAR28141.1 - 0.9 9.7 7.8 8.7 6.6 1.2 2.7 1 1 1 2 2 2 0 Protein of unknown function DUF16 Psu PF07455.6 CAR28141.1 - 2 7.8 5.0 5.6 6.4 0.4 2.6 2 1 1 3 3 3 0 Phage polarity suppression protein (Psu) DivIVA PF05103.8 CAR28141.1 - 2.8 7.9 9.1 2.6 8.1 2.4 2.9 2 1 1 3 3 3 0 DivIVA protein ATP_sub_h PF10775.4 CAR28142.1 - 8.5e-24 83.0 0.2 1.2e-23 82.5 0.2 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h K1 PF02960.9 CAR28143.1 - 0.017 15.1 0.0 0.02 14.9 0.0 1.1 1 0 0 1 1 1 0 K1 glycoprotein IncA PF04156.9 CAR28143.1 - 0.019 14.6 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 IncA protein TRP PF06011.7 CAR28143.1 - 0.02 13.4 0.0 0.025 13.1 0.0 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel DUF4366 PF14283.1 CAR28143.1 - 0.046 13.1 0.1 0.05 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) PBP1_TM PF14812.1 CAR28143.1 - 0.05 13.9 4.0 0.088 13.1 2.7 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.1 CAR28143.1 - 0.064 12.9 0.0 0.086 12.5 0.0 1.2 1 0 0 1 1 1 0 FAM176 family TerC PF03741.11 CAR28143.1 - 0.17 11.3 3.3 0.36 10.2 2.3 1.6 1 1 1 2 2 2 0 Integral membrane protein TerC family zf-U1 PF06220.7 CAR28144.1 - 2.1e-18 65.6 5.2 4.4e-18 64.5 3.6 1.6 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_2 PF12756.2 CAR28144.1 - 0.049 13.7 1.0 0.088 12.9 0.7 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-Dof PF02701.10 CAR28144.1 - 0.17 11.7 4.4 6 6.8 0.2 2.4 2 0 0 2 2 2 0 Dof domain, zinc finger zf-C2H2_jaz PF12171.3 CAR28144.1 - 0.18 11.9 6.1 0.79 9.9 4.2 2.2 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding GTP_EFTU PF00009.22 CAR28145.1 - 1.3e-61 207.3 0.2 1.7e-61 206.9 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CAR28145.1 - 8.8e-27 93.1 0.0 2.3e-26 91.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CAR28145.1 - 7.3e-21 74.0 1.7 1.9e-20 72.7 0.9 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CAR28145.1 - 6.3e-06 25.7 0.2 1.7e-05 24.3 0.1 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 CAR28145.1 - 1.3e-05 25.1 0.0 2.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CAR28145.1 - 0.00033 21.1 0.0 0.00057 20.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 CAR28145.1 - 0.01 15.3 0.4 4.8 6.6 0.0 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation CbiA PF01656.18 CAR28145.1 - 0.13 11.6 3.0 7.4 5.9 0.8 2.2 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain G_glu_transpept PF01019.16 CAR28146.1 - 3.3e-136 454.7 0.0 3.9e-136 454.5 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF1708 PF08101.6 CAR28147.1 - 1.4e-154 514.9 8.8 5e-154 513.1 6.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1708) RhoGAP PF00620.22 CAR28147.1 - 0.057 13.0 0.4 0.26 10.9 0.0 2.3 3 0 0 3 3 3 0 RhoGAP domain CT47 PF15623.1 CAR28148.1 - 0.068 12.9 31.2 0.083 12.6 21.6 1.0 1 0 0 1 1 1 0 Cancer/testis gene family 47 CENP-T PF15511.1 CAR28148.1 - 0.25 10.5 30.3 0.27 10.4 21.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Raftlin PF15250.1 CAR28148.1 - 0.39 9.1 17.0 0.55 8.6 11.8 1.2 1 0 0 1 1 1 0 Raftlin Hid1 PF12722.2 CAR28148.1 - 0.82 7.2 20.1 0.8 7.3 13.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SprA-related PF12118.3 CAR28148.1 - 0.94 8.7 27.5 1.3 8.3 19.1 1.2 1 0 0 1 1 1 0 SprA-related family Merozoite_SPAM PF07133.6 CAR28148.1 - 1.9 8.3 51.1 4 7.3 35.4 1.5 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Ycf1 PF05758.7 CAR28148.1 - 5.6 4.5 22.9 6 4.4 15.8 1.1 1 0 0 1 1 1 0 Ycf1 Cellulase PF00150.13 CAR28149.1 - 1.3e-13 50.7 1.8 2.8e-13 49.6 0.9 1.6 1 1 1 2 2 2 1 Cellulase (glycosyl hydrolase family 5) SNF2_N PF00176.18 CAR28150.1 - 9.2e-70 234.7 0.2 1.6e-69 233.9 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CAR28150.1 - 1.5e-12 47.2 0.0 1e-11 44.5 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 CAR28150.1 - 2.3e-05 24.0 6.3 9.9e-05 21.9 4.5 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CAR28150.1 - 0.00018 21.4 2.7 0.00052 19.9 1.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CAR28150.1 - 0.00044 20.0 5.8 0.0009 19.0 4.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CAR28150.1 - 0.0041 16.7 5.5 0.0091 15.6 3.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CAR28150.1 - 0.0068 16.0 1.1 0.026 14.2 0.8 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 CAR28150.1 - 0.03 13.9 6.4 0.072 12.7 4.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cellulase PF00150.13 CAR28152.1 - 7.9e-12 44.9 0.0 2.4e-07 30.2 0.0 2.5 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) DUF303 PF03629.13 CAR28152.1 - 0.1 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF303) DNA_primase_S PF01896.14 CAR28153.1 - 1.5e-55 186.9 0.1 2.8e-55 186.1 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit Scramblase PF03803.10 CAR28153.1 - 0.087 11.8 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Scramblase HSP20 PF00011.16 CAR28154.1 - 8.5e-22 76.9 2.7 1.3e-21 76.3 1.9 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Proteasome PF00227.21 CAR28155.1 - 7.7e-41 139.4 0.0 9e-41 139.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit OB_NTP_bind PF07717.11 CAR28156.1 - 2.5e-26 91.7 0.0 6.5e-26 90.3 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CAR28156.1 - 2.5e-24 85.2 0.0 8e-24 83.6 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CAR28156.1 - 4.7e-13 48.7 0.0 1.4e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 CAR28156.1 - 6.9e-13 48.5 0.1 1.9e-12 47.1 0.1 1.8 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 CAR28156.1 - 5.5e-06 25.9 0.1 1.7e-05 24.3 0.1 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CAR28156.1 - 1.3e-05 25.3 0.0 3.5e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 CAR28156.1 - 0.00013 20.9 0.4 0.00095 18.1 0.6 2.2 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.1 CAR28156.1 - 0.0016 18.0 0.0 0.0016 18.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CAR28156.1 - 0.0076 16.1 0.1 0.084 12.7 0.1 2.6 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 CAR28156.1 - 0.0085 14.9 0.6 0.02 13.7 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain ResIII PF04851.10 CAR28156.1 - 0.01 15.6 0.2 1.3 8.8 0.0 2.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit SRP54 PF00448.17 CAR28156.1 - 0.016 14.6 0.0 0.04 13.3 0.0 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.1 CAR28156.1 - 0.026 14.2 0.1 0.067 12.9 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Arch_ATPase PF01637.13 CAR28156.1 - 0.033 13.8 0.0 0.12 12.0 0.0 2.0 1 0 0 1 1 1 0 Archaeal ATPase AAA PF00004.24 CAR28156.1 - 0.055 13.6 0.3 0.26 11.4 0.0 2.4 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 CAR28156.1 - 0.19 12.0 0.1 0.19 12.0 0.1 3.5 2 2 1 3 3 2 0 ABC transporter AAA_23 PF13476.1 CAR28156.1 - 0.57 10.4 0.0 0.57 10.4 0.0 2.8 2 1 0 2 2 1 0 AAA domain NAD_binding_8 PF13450.1 CAR28157.1 - 3.5e-12 46.1 0.0 8.7e-12 44.8 0.0 1.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 CAR28157.1 - 1.7e-07 30.6 0.3 8.9e-07 28.3 0.2 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 CAR28157.1 - 9.4e-05 21.4 0.0 0.00017 20.6 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 CAR28157.1 - 0.00022 21.5 0.1 0.0024 18.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CAR28157.1 - 0.0019 17.3 0.0 0.0039 16.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Mqo PF06039.10 CAR28157.1 - 0.011 13.8 0.0 0.25 9.4 0.0 2.2 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.1 CAR28157.1 - 0.016 15.0 0.0 0.077 12.7 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CAR28157.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RRM_5 PF13893.1 CAR28158.1 - 1.4e-12 47.2 0.0 2.1e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAR28158.1 - 2.4e-11 43.0 0.0 5.2e-11 42.0 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR28158.1 - 4.4e-09 36.1 0.0 7.8e-09 35.3 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.6 CAR28158.1 - 0.056 12.9 0.1 0.056 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) AMP-binding PF00501.23 CAR28159.1 - 3.6e-66 223.2 0.0 4.7e-66 222.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme EB1 PF03271.12 CAR28160.1 - 1.1e-18 66.9 0.5 2.2e-18 65.9 0.3 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 CAR28160.1 - 4.8e-07 29.7 1.1 1e-06 28.7 0.8 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF1202 PF06717.6 CAR28160.1 - 0.0078 15.5 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1202) Peptidase_M41 PF01434.13 CAR28161.1 - 5.1e-76 254.8 0.1 7.4e-76 254.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CAR28161.1 - 6.5e-43 146.0 0.0 1.5e-42 144.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CAR28161.1 - 0.00055 20.7 0.0 0.0024 18.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain FtsH_ext PF06480.10 CAR28161.1 - 0.00091 19.3 0.1 0.0025 17.9 0.1 1.7 1 0 0 1 1 1 1 FtsH Extracellular TIP49 PF06068.8 CAR28161.1 - 0.0023 16.7 0.0 0.0062 15.3 0.0 1.7 1 0 0 1 1 1 1 TIP49 C-terminus AAA_22 PF13401.1 CAR28161.1 - 0.003 17.7 2.1 0.09 12.9 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CAR28161.1 - 0.0031 17.2 0.8 0.0097 15.6 0.6 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 CAR28161.1 - 0.0033 17.1 0.4 0.033 13.9 0.1 2.8 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 CAR28161.1 - 0.007 15.7 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 CAR28161.1 - 0.008 16.1 0.4 0.037 13.9 0.3 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 CAR28161.1 - 0.01 15.7 0.1 0.11 12.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 CAR28161.1 - 0.011 14.7 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 CAR28161.1 - 0.019 14.1 0.0 0.045 12.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 CAR28161.1 - 0.027 14.7 0.2 0.32 11.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CAR28161.1 - 0.054 12.8 1.4 0.18 11.2 0.5 2.2 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.1 CAR28161.1 - 0.09 12.6 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 CAR28161.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain HMG_box PF00505.14 CAR28162.1 - 3.3e-15 56.0 6.6 1.4e-14 54.0 4.6 2.0 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CAR28162.1 - 1.2e-05 25.5 1.9 3.5e-05 24.0 1.3 1.8 1 1 0 1 1 1 1 HMG-box domain Ribosomal_S5 PF00333.15 CAR28163.1 - 2.6e-25 87.9 0.1 4.8e-25 87.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 CAR28163.1 - 5.6e-17 60.7 0.0 9.7e-17 60.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain dUTPase PF00692.14 CAR28164.1 - 7.1e-44 148.3 0.1 7.9e-44 148.2 0.0 1.0 1 0 0 1 1 1 1 dUTPase Med22 PF06179.7 CAR28165.1 - 4.7e-21 74.8 0.2 5.8e-21 74.5 0.2 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex HeLo PF14479.1 CAR28165.1 - 0.0089 15.7 0.1 0.011 15.4 0.0 1.1 1 0 0 1 1 1 1 Prion-inhibition and propagation MIS13 PF08202.6 CAR28166.1 - 3.8e-54 183.8 14.0 5.1e-54 183.3 9.7 1.2 1 0 0 1 1 1 1 Mis12-Mtw1 protein family HalX PF08663.5 CAR28166.1 - 0.072 13.0 2.7 2.2 8.2 0.8 2.7 2 0 0 2 2 2 0 HalX domain Sedlin_N PF04628.8 CAR28167.1 - 4.3e-49 165.7 0.0 5.8e-49 165.3 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 CAR28167.1 - 1.8e-06 27.7 0.0 3.7e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 Sybindin-like family Innate_immun PF12782.2 CAR28168.1 - 0.25 10.5 11.4 0.44 9.7 7.9 1.5 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Cut8_C PF08559.5 CAR28170.1 - 1.1e-42 145.2 0.5 1.8e-42 144.5 0.4 1.4 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 CAR28170.1 - 8.4e-06 25.4 0.6 2.6e-05 23.9 0.4 1.9 1 0 0 1 1 1 1 Cut8 dimerisation domain WD40 PF00400.27 CAR28171.1 - 1.1e-08 34.6 4.2 0.0067 16.2 0.1 6.0 7 0 0 7 7 7 3 WD domain, G-beta repeat PQQ_2 PF13360.1 CAR28171.1 - 1.8e-07 30.8 1.4 7e-06 25.6 1.0 2.7 1 1 0 1 1 1 1 PQQ-like domain Apc4_WD40 PF12894.2 CAR28171.1 - 3.9e-05 23.0 0.0 0.0058 16.1 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.16 CAR28171.1 - 0.0055 16.1 0.5 3 7.5 0.0 3.4 4 0 0 4 4 4 2 PQQ enzyme repeat DUF4479 PF14794.1 CAR28171.1 - 0.07 12.6 0.1 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4479) RAB3GAP2_N PF14655.1 CAR28171.1 - 0.13 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Lum_binding PF00677.12 CAR28172.1 - 1.4e-48 162.6 4.2 1.2e-23 82.7 0.2 2.3 2 0 0 2 2 2 2 Lumazine binding domain Asp PF00026.18 CAR28173.1 - 1.7e-71 241.0 0.2 1.7e-71 241.0 0.1 1.4 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CAR28173.1 - 7.1e-07 29.3 4.5 8.2e-07 29.1 0.1 2.3 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal BAG PF02179.11 CAR28174.1 - 3.3e-16 59.1 0.2 5e-16 58.5 0.1 1.3 1 0 0 1 1 1 1 BAG domain CDC37_N PF03234.9 CAR28174.1 - 0.037 14.3 0.9 0.049 13.9 0.6 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Peptidase_C98 PF15499.1 CAR28174.1 - 0.058 12.6 0.6 0.09 12.0 0.1 1.5 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase PAF-AH_p_II PF03403.8 CAR28174.1 - 0.083 11.1 0.3 0.14 10.4 0.2 1.3 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II HEAT PF02985.17 CAR28175.1 - 0.0053 16.7 0.0 0.56 10.4 0.0 3.3 2 0 0 2 2 2 1 HEAT repeat Astro_capsid PF03115.9 CAR28175.1 - 1 7.5 3.1 1.3 7.2 2.2 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Sporozoite_P67 PF05642.6 CAR28175.1 - 2.4 5.9 3.6 3.5 5.3 2.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAD_binding_1 PF00667.15 CAR28176.1 - 5.3e-67 225.4 0.0 8.1e-67 224.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 CAR28176.1 - 1.1e-09 38.7 0.0 1.5e-08 35.1 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain SMC_N PF02463.14 CAR28177.1 - 6.1e-72 241.4 0.0 7.7e-71 237.8 0.0 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CAR28177.1 - 9.3e-23 80.4 0.9 2.4e-22 79.1 0.1 2.1 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 CAR28177.1 - 5.7e-16 59.4 2.6 5.7e-16 59.4 1.8 6.2 3 2 0 4 4 1 1 AAA domain AAA_21 PF13304.1 CAR28177.1 - 5.7e-11 42.9 3.3 5.1e-06 26.6 0.3 5.0 4 2 0 5 5 5 2 AAA domain AAA_13 PF13166.1 CAR28177.1 - 3.1e-06 25.9 25.9 3.1e-06 25.9 18.0 5.9 4 2 2 6 6 6 4 AAA domain AAA_29 PF13555.1 CAR28177.1 - 2.5e-05 23.7 0.3 0.00013 21.3 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 CAR28177.1 - 0.00031 20.0 26.1 0.029 13.5 4.3 4.6 3 2 0 4 4 4 3 Reovirus sigma C capsid protein Mod_r PF07200.8 CAR28177.1 - 0.0027 17.6 8.1 0.0027 17.6 5.6 6.9 3 2 4 7 7 7 1 Modifier of rudimentary (Mod(r)) protein IncA PF04156.9 CAR28177.1 - 0.0047 16.5 23.9 0.0047 16.5 16.6 7.1 3 2 3 7 7 6 2 IncA protein Pox_A21 PF05323.7 CAR28177.1 - 0.017 15.5 1.0 7 7.0 0.0 3.0 2 0 0 2 2 2 0 Poxvirus A21 Protein Spc7 PF08317.6 CAR28177.1 - 5.3 5.6 99.6 0.031 12.9 14.9 6.1 3 2 3 6 6 6 0 Spc7 kinetochore protein Ribosomal_L2_C PF03947.13 CAR28178.1 - 1.7e-40 137.8 2.9 2.5e-40 137.2 2.0 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CAR28178.1 - 1.6e-12 47.1 0.2 1.6e-12 47.1 0.1 1.8 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain RRM_6 PF14259.1 CAR28179.1 - 9.9e-22 76.7 0.1 3.7e-14 52.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAR28179.1 - 1.2e-19 69.6 0.7 4.8e-13 48.5 0.1 3.1 2 2 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR28179.1 - 3.4e-10 39.6 0.0 0.00014 21.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF258 PF03193.11 CAR28179.1 - 0.0076 15.4 0.8 0.014 14.6 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 DbpA PF03880.10 CAR28179.1 - 0.19 11.4 0.8 1.6 8.4 0.1 2.6 3 0 0 3 3 3 0 DbpA RNA binding domain UCR_hinge PF02320.11 CAR28180.1 - 4.2e-25 87.4 1.7 4.2e-25 87.4 1.2 1.6 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein Nop14 PF04147.7 CAR28180.1 - 0.026 12.4 18.0 0.028 12.3 12.4 1.0 1 0 0 1 1 1 0 Nop14-like family DUF506 PF04720.7 CAR28180.1 - 0.16 11.5 1.9 0.18 11.4 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF506) CDC45 PF02724.9 CAR28180.1 - 0.22 9.5 9.3 0.23 9.4 6.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Nro1 PF12753.2 CAR28180.1 - 0.77 8.6 8.5 0.48 9.3 5.0 1.3 1 1 0 1 1 1 0 Nuclear pore complex subunit Nro1 NOA36 PF06524.7 CAR28180.1 - 1.5 8.0 14.0 1.9 7.6 9.7 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-T PF15511.1 CAR28180.1 - 1.5 8.0 13.6 1.6 7.8 9.5 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T RRN3 PF05327.6 CAR28180.1 - 1.5 6.8 5.7 1.5 6.8 4.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2457 PF10446.4 CAR28180.1 - 2.5 6.7 21.5 2.8 6.5 14.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sigma70_ner PF04546.8 CAR28180.1 - 2.6 7.6 19.4 5.7 6.4 13.5 1.6 1 1 0 1 1 1 0 Sigma-70, non-essential region Mpp10 PF04006.7 CAR28180.1 - 3.5 5.8 19.2 3.9 5.7 13.3 1.0 1 0 0 1 1 1 0 Mpp10 protein CobT PF06213.7 CAR28180.1 - 3.6 6.6 19.1 4.3 6.3 13.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Paf1 PF03985.8 CAR28180.1 - 7.9 5.0 13.7 8.1 5.0 9.5 1.2 1 0 0 1 1 1 0 Paf1 DUF1510 PF07423.6 CAR28180.1 - 8.6 5.6 11.9 9.5 5.5 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SDA1 PF05285.7 CAR28180.1 - 9.7 5.3 18.2 10 5.2 12.6 1.1 1 0 0 1 1 1 0 SDA1 HLH PF00010.21 CAR28181.1 - 8.3e-13 47.8 0.1 1.8e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Prothymosin PF03247.9 CAR28182.1 - 4.5 7.4 27.9 2.6 8.2 14.7 2.4 2 0 0 2 2 2 0 Prothymosin/parathymosin family DNA_pol_phi PF04931.8 CAR28182.1 - 7.2 4.2 20.2 10 3.7 14.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi His_biosynth PF00977.16 CAR28183.1 - 2.9e-25 88.8 0.0 3.7e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Chordopox_A13L PF05961.6 CAR28183.1 - 0.09 12.7 0.3 0.2 11.6 0.2 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Aldolase PF01081.14 CAR28183.1 - 0.13 11.4 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 KDPG and KHG aldolase RNA_pol_A_bac PF01000.21 CAR28184.1 - 2.7e-32 111.2 0.1 5.7e-32 110.1 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CAR28184.1 - 1.1e-12 46.8 0.0 1.7e-12 46.2 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Tim44 PF04280.10 CAR28186.1 - 8.4e-32 110.1 0.1 2.5e-31 108.6 0.0 1.9 2 0 0 2 2 2 1 Tim44-like domain Peptidase_C48 PF02902.14 CAR28187.1 - 3.7e-41 141.1 3.4 3.7e-41 141.1 2.4 2.0 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain RINGv PF12906.2 CAR28188.1 - 3.3e-13 49.4 6.2 5.9e-13 48.6 4.3 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 CAR28188.1 - 0.28 11.0 5.4 0.55 10.1 3.7 1.5 1 0 0 1 1 1 0 Ring finger domain FANCL_C PF11793.3 CAR28188.1 - 0.41 10.6 4.2 0.84 9.6 2.9 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain DUF342 PF03961.8 CAR28189.1 - 0.6 8.4 9.6 0.95 7.7 6.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APC_CDC26 PF10471.4 CAR28190.1 - 1e-15 58.2 0.9 1e-15 58.2 0.6 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex APC subunit 1 TBPIP PF07106.8 CAR28190.1 - 0.07 12.6 0.3 0.11 12.0 0.2 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) MMgT PF10270.4 CAR28191.1 - 1.2e-24 86.7 0.2 1.5e-24 86.4 0.1 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter MKT1_N PF12247.3 CAR28191.1 - 0.026 14.8 0.1 0.053 13.8 0.0 1.6 2 0 0 2 2 2 0 Temperature dependent protein affecting M2 dsRNA replication STAG PF08514.6 CAR28192.1 - 1.1e-06 28.3 0.1 3.4e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 STAG domain HEAT PF02985.17 CAR28192.1 - 0.00023 20.9 0.5 0.71 10.1 0.1 3.6 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.1 CAR28192.1 - 0.0012 19.0 0.0 0.0037 17.5 0.0 1.8 1 0 0 1 1 1 1 HEAT repeats Erf4 PF10256.4 CAR28192.1 - 0.0051 16.6 0.5 0.28 11.0 0.0 3.3 2 1 1 3 3 3 1 Golgin subfamily A member 7/ERF4 family RasGEF_N PF00618.15 CAR28192.1 - 0.88 9.7 7.2 4 7.5 0.2 4.3 4 1 0 4 4 4 0 RasGEF N-terminal motif YihI PF04220.7 CAR28192.1 - 4.1 6.6 11.3 1 8.6 4.9 2.2 2 0 0 2 2 2 0 Der GTPase activator (YihI) YABBY PF04690.8 CAR28193.1 - 0.048 13.8 0.0 0.079 13.2 0.0 1.3 1 0 0 1 1 1 0 YABBY protein DUF2746 PF10874.3 CAR28193.1 - 0.16 12.2 2.2 0.35 11.0 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) Zip PF02535.17 CAR28194.1 - 2.8e-56 190.8 10.1 2.3e-37 128.6 1.5 2.6 2 1 1 3 3 3 2 ZIP Zinc transporter PTS_EIIC_2 PF13303.1 CAR28194.1 - 0.003 16.4 1.0 0.0075 15.1 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase system, EIIC FtsX PF02687.16 CAR28194.1 - 3.5 7.4 12.2 6.8 6.4 2.1 3.3 2 1 1 3 3 3 0 FtsX-like permease family SWIRM PF04433.12 CAR28195.1 - 9.8e-33 112.1 0.1 2.7e-32 110.7 0.1 1.8 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 CAR28195.1 - 1.7e-14 53.0 3.4 2.6e-14 52.4 2.3 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 CAR28195.1 - 2.2e-06 27.6 0.2 4.4e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CAR28195.1 - 5.2e-06 26.4 0.0 3.3e-05 23.9 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Elf1 PF05129.8 CAR28195.1 - 0.028 14.1 0.3 0.072 12.7 0.2 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like SNF2_N PF00176.18 CAR28196.1 - 1.9e-68 230.4 0.2 3.3e-68 229.6 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CAR28196.1 - 6.9e-17 61.0 0.0 4.1e-15 55.4 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 CAR28196.1 - 8.7e-09 34.6 0.5 2.2e-08 33.2 0.3 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 CAR28196.1 - 4.8e-05 22.9 0.0 0.00017 21.0 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CAR28196.1 - 0.021 14.9 0.0 0.14 12.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain cNMP_binding PF00027.24 CAR28197.1 - 6.9e-41 137.9 0.1 1.3e-20 73.0 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 CAR28197.1 - 8.7e-12 44.2 2.8 8.7e-12 44.2 1.9 2.1 2 0 0 2 2 2 1 Regulatory subunit of type II PKA R-subunit CFTR_R PF14396.1 CAR28197.1 - 0.056 12.7 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 Cystic fibrosis TM conductance regulator (CFTR), regulator domain Erg28 PF03694.8 CAR28198.1 - 4e-44 149.1 1.2 5.1e-44 148.8 0.9 1.1 1 0 0 1 1 1 1 Erg28 like protein F_actin_cap_B PF01115.12 CAR28199.1 - 3.8e-98 327.5 0.3 4.4e-98 327.2 0.2 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Pkinase PF00069.20 CAR28200.1 - 2.2e-53 181.0 4.7 7.5e-52 176.0 3.3 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR28200.1 - 1.2e-18 67.1 1.2 3.6e-14 52.4 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CAR28200.1 - 3.2e-05 23.7 0.6 0.00011 22.0 0.1 2.0 2 1 0 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CAR28200.1 - 0.0012 18.5 1.1 0.0037 16.8 0.8 1.9 1 1 0 1 1 1 1 Choline/ethanolamine kinase DUF496 PF04363.7 CAR28200.1 - 0.012 15.3 4.9 0.086 12.6 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF496) PC_rep PF01851.17 CAR28200.1 - 0.049 13.8 0.7 12 6.3 0.1 2.9 2 0 0 2 2 2 0 Proteasome/cyclosome repeat bZIP_1 PF00170.16 CAR28202.1 - 3.4e-14 52.5 2.7 7.6e-14 51.4 1.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CAR28202.1 - 0.00012 21.7 6.2 0.0003 20.5 4.3 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 CAR28202.1 - 0.0033 17.6 0.3 0.0068 16.6 0.2 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor Totivirus_coat PF05518.6 CAR28202.1 - 0.04 11.7 3.2 0.054 11.3 2.2 1.1 1 0 0 1 1 1 0 Totivirus coat protein Bac_rhodopsin PF01036.13 CAR28203.1 - 6.6e-06 25.5 0.5 7.6e-06 25.3 0.3 1.2 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4476 PF14771.1 CAR28204.1 - 0.009 16.0 0.2 0.034 14.1 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4476) Pex24p PF06398.6 CAR28204.1 - 2.5 6.8 6.6 3.9 6.1 4.6 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Not3 PF04065.10 CAR28206.1 - 3e-92 308.1 28.9 3e-92 308.1 20.0 2.0 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 CAR28206.1 - 4.2e-27 94.6 0.2 1.6e-26 92.7 0.2 2.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family TauD PF02668.11 CAR28207.1 - 9.1e-47 159.8 0.1 1.8e-46 158.9 0.0 1.4 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 CAR28207.1 - 0.048 14.1 0.9 1.2 9.7 0.0 2.6 2 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily AAA PF00004.24 CAR28208.1 - 2.5e-39 134.4 0.0 4.4e-39 133.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 CAR28208.1 - 1.7e-08 34.2 0.0 4e-06 26.6 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 CAR28208.1 - 1.5e-05 25.1 0.1 0.00038 20.5 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 CAR28208.1 - 7.6e-05 22.6 0.1 0.00019 21.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 CAR28208.1 - 7.9e-05 21.8 0.0 0.00014 21.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CAR28208.1 - 0.00021 21.3 0.2 0.032 14.2 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 CAR28208.1 - 0.00068 19.3 0.0 0.003 17.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CAR28208.1 - 0.0036 17.1 0.0 0.0082 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 CAR28208.1 - 0.0063 15.2 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 CAR28208.1 - 0.0064 16.3 0.0 0.037 13.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CAR28208.1 - 0.0066 15.6 1.1 0.011 14.8 0.1 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 CAR28208.1 - 0.0068 15.8 0.1 0.34 10.2 0.0 2.6 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CAR28208.1 - 0.0073 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Arch_ATPase PF01637.13 CAR28208.1 - 0.0082 15.8 0.0 1.3 8.6 0.0 2.8 1 1 1 2 2 2 1 Archaeal ATPase Chromo PF00385.19 CAR28208.1 - 0.016 14.8 1.5 0.027 14.1 0.0 2.2 3 0 0 3 3 2 0 Chromo (CHRromatin Organisation MOdifier) domain AAA_24 PF13479.1 CAR28208.1 - 0.019 14.5 0.2 0.047 13.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 CAR28208.1 - 0.03 13.2 0.0 0.071 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_19 PF13245.1 CAR28208.1 - 0.039 13.7 0.0 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain AAA_28 PF13521.1 CAR28208.1 - 0.044 13.7 1.0 0.2 11.5 0.0 2.5 3 0 0 3 3 2 0 AAA domain NACHT PF05729.7 CAR28208.1 - 0.07 12.7 0.0 0.2 11.2 0.0 1.8 1 1 0 1 1 1 0 NACHT domain PhoH PF02562.11 CAR28208.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.1 CAR28208.1 - 0.3 11.3 5.8 0.66 10.2 0.0 3.5 3 2 0 3 3 3 0 AAA domain AAA_17 PF13207.1 CAR28208.1 - 0.44 11.3 0.0 0.44 11.3 0.0 3.3 4 1 0 4 4 2 0 AAA domain Metallophos PF00149.23 CAR28209.1 - 5.4e-28 97.7 8.7 8.7e-28 97.0 6.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DnaJ-X PF14308.1 CAR28210.1 - 1.2e-60 204.3 6.7 1.2e-60 204.3 4.6 2.3 2 1 1 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 CAR28210.1 - 1.4e-24 85.5 0.7 1.4e-24 85.5 0.5 3.1 3 0 0 3 3 3 1 DnaJ domain Spore_YhcN_YlaJ PF09580.5 CAR28210.1 - 0.11 12.6 0.2 0.11 12.6 0.1 2.0 2 1 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) YflT PF11181.3 CAR28210.1 - 0.11 12.6 0.2 0.11 12.6 0.2 3.1 4 1 1 5 5 5 0 Heat induced stress protein YflT CobN-Mg_chel PF02514.11 CAR28210.1 - 0.17 9.2 8.7 0.21 8.9 6.0 1.1 1 0 0 1 1 1 0 CobN/Magnesium Chelatase Apq12 PF12716.2 CAR28211.1 - 1e-06 28.3 14.5 2.2e-06 27.2 10.0 1.6 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis Peptidase_M50B PF13398.1 CAR28211.1 - 0.1 11.9 6.4 0.14 11.5 4.4 1.2 1 0 0 1 1 1 0 Peptidase M50B-like Pex24p PF06398.6 CAR28211.1 - 0.37 9.5 5.6 0.38 9.5 3.9 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Wzy_C PF04932.10 CAR28211.1 - 0.39 10.4 4.5 0.43 10.3 3.1 1.2 1 0 0 1 1 1 0 O-Antigen ligase Complex1_LYR PF05347.10 CAR28212.1 - 1.5e-16 59.8 1.0 2e-16 59.5 0.7 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CAR28212.1 - 1.6e-16 60.2 1.1 2e-16 59.9 0.7 1.1 1 0 0 1 1 1 1 Complex1_LYR-like DUF1851 PF08906.6 CAR28212.1 - 0.14 12.1 0.2 0.36 10.8 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1851) Ofd1_CTDD PF10637.4 CAR28213.1 - 2.1e-91 305.7 3.2 7.1e-88 294.1 2.0 2.3 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 CAR28213.1 - 2.3e-14 53.6 0.1 6e-14 52.3 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily BAR_2 PF10455.4 CAR28214.1 - 9e-78 261.0 9.8 1.3e-77 260.6 5.6 1.9 1 1 1 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 CAR28214.1 - 3.8e-15 56.0 8.4 9e-15 54.8 5.8 1.7 1 1 0 1 1 1 1 BAR domain BCDHK_Adom3 PF10436.4 CAR28215.1 - 2.3e-28 98.7 1.7 5.1e-28 97.6 1.0 1.7 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CAR28215.1 - 1.3e-19 69.9 0.0 2.4e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CAR28215.1 - 1.9e-06 27.6 0.0 3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 CAR28215.1 - 0.00022 20.9 0.0 0.00046 19.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain Ribosomal_S18 PF01084.15 CAR28216.1 - 4.3e-18 64.9 0.1 1.3e-17 63.4 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S18 Cupin_8 PF13621.1 CAR28217.1 - 7.7e-10 38.6 1.0 5.8e-09 35.8 0.6 2.3 1 1 0 1 1 1 1 Cupin-like domain PHD PF00628.24 CAR28217.1 - 4.5e-06 26.2 5.8 8.9e-06 25.3 4.0 1.5 1 0 0 1 1 1 1 PHD-finger DUF1423 PF07227.6 CAR28217.1 - 0.0004 19.1 1.0 0.00074 18.2 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1423) JmjC PF02373.17 CAR28217.1 - 0.00049 20.3 0.0 0.015 15.5 0.0 3.0 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 CAR28217.1 - 0.012 14.8 0.5 0.019 14.2 0.0 1.6 2 0 0 2 2 2 0 Cupin superfamily protein zf-HC5HC2H_2 PF13832.1 CAR28217.1 - 0.086 12.8 2.0 0.15 12.0 1.4 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain C1_1 PF00130.17 CAR28217.1 - 0.28 10.9 4.7 0.72 9.6 3.3 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.1 CAR28217.1 - 0.32 11.1 3.2 0.5 10.5 1.8 1.7 2 0 0 2 2 2 0 PHD-like zinc-binding domain NAD_binding_1 PF00175.16 CAR28218.1 - 3.9e-31 107.8 0.0 6.1e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CAR28218.1 - 3.9e-28 97.4 0.0 6.3e-28 96.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 CAR28218.1 - 5.6e-06 26.3 0.0 0.0025 17.7 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain AA_kinase PF00696.23 CAR28219.1 - 7.1e-40 137.0 0.0 1.1e-39 136.3 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 CAR28219.1 - 4.1e-12 45.3 1.0 8.7e-08 31.4 0.2 2.9 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.1 CAR28219.1 - 6.1e-07 28.8 2.2 8.5e-05 22.0 0.6 2.4 2 0 0 2 2 2 2 ACT domain Cyt-b5 PF00173.23 CAR28220.1 - 7.4e-20 70.5 0.0 1.9e-18 66.0 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain RR_TM4-6 PF06459.7 CAR28220.1 - 0.034 14.0 0.0 0.048 13.5 0.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ArfGap PF01412.13 CAR28221.1 - 2.2e-37 127.4 1.4 2.3e-37 127.3 0.1 1.6 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Mito_carr PF00153.22 CAR28222.1 - 6e-50 166.9 3.3 7e-17 60.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CBM_21 PF03370.8 CAR28223.1 - 1.7e-27 95.6 0.1 2.6e-27 95.0 0.1 1.3 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit CBM_25 PF03423.8 CAR28223.1 - 0.075 13.1 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) WD40 PF00400.27 CAR28224.1 - 2.5e-49 163.4 24.4 4.4e-10 39.0 0.9 7.5 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 CAR28224.1 - 2.2e-12 46.4 1.4 5.5e-12 45.2 1.0 1.7 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 CAR28224.1 - 8.2e-11 40.7 9.3 0.047 11.8 0.0 5.6 1 1 5 6 6 6 5 Nucleoporin Nup120/160 F-box PF00646.28 CAR28224.1 - 7.5e-10 38.2 0.8 1.7e-09 37.0 0.5 1.7 1 0 0 1 1 1 1 F-box domain Nucleoporin_N PF08801.6 CAR28224.1 - 0.00013 20.8 0.9 1 8.0 0.0 3.7 3 1 0 3 3 3 2 Nup133 N terminal like PRANC PF09372.5 CAR28224.1 - 0.038 13.9 0.1 0.082 12.8 0.0 1.7 1 0 0 1 1 1 0 PRANC domain PQQ_2 PF13360.1 CAR28224.1 - 0.077 12.4 0.2 1.9 7.8 0.0 2.2 2 0 0 2 2 2 0 PQQ-like domain HisG PF01634.13 CAR28225.1 - 3.9e-52 176.1 0.2 5.9e-52 175.5 0.1 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 CAR28225.1 - 1.5e-28 98.5 0.0 2.5e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 HisG, C-terminal domain EXS PF03124.9 CAR28226.1 - 1.5e-84 283.9 22.2 2.4e-84 283.3 15.4 1.3 1 0 0 1 1 1 1 EXS family SPX PF03105.14 CAR28226.1 - 5.8e-38 131.2 8.6 1.2e-37 130.2 5.9 1.5 1 0 0 1 1 1 1 SPX domain DUF106 PF01956.11 CAR28226.1 - 0.011 15.2 0.4 0.011 15.2 0.3 2.8 2 1 1 3 3 3 0 Integral membrane protein DUF106 E1-E2_ATPase PF00122.15 CAR28227.1 - 2.1e-28 98.9 0.0 2.1e-28 98.9 0.0 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CAR28227.1 - 4.4e-14 53.4 0.0 2e-13 51.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CAR28227.1 - 1.6e-11 44.7 0.1 3.7e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CAR28227.1 - 2.7e-09 36.8 0.0 8.3e-09 35.2 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CAR28227.1 - 0.0057 16.2 0.2 0.022 14.3 0.0 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Steroid_dh PF02544.11 CAR28228.1 - 2.5e-07 30.5 1.2 2.5e-07 30.5 0.8 2.1 1 1 2 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase Transp_cyt_pur PF02133.10 CAR28229.1 - 7.1e-87 291.7 30.7 8.3e-87 291.5 21.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Ribosomal_L34e PF01199.13 CAR28230.1 - 2.9e-35 120.3 5.3 2.9e-35 120.3 3.7 1.6 2 0 0 2 2 2 1 Ribosomal protein L34e Zn_ribbon_recom PF13408.1 CAR28230.1 - 0.031 14.5 0.3 0.08 13.2 0.2 1.8 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-3CxxC PF13695.1 CAR28230.1 - 0.33 11.2 4.0 0.75 10.0 2.1 1.9 1 1 1 2 2 2 0 Zinc-binding domain ATG27 PF09451.5 CAR28232.1 - 2.4e-61 207.3 0.0 3.1e-61 206.9 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 HTH_36 PF13730.1 CAR28232.1 - 0.018 15.1 0.2 3.7 7.7 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_psq PF05225.11 CAR28232.1 - 0.16 11.5 0.2 0.28 10.7 0.1 1.4 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Prefoldin_2 PF01920.15 CAR28233.1 - 5.5e-13 48.5 8.3 6.2e-13 48.4 5.7 1.0 1 0 0 1 1 1 1 Prefoldin subunit NPR2 PF06218.6 CAR28233.1 - 0.0063 15.2 0.3 0.0085 14.8 0.2 1.1 1 0 0 1 1 1 1 Nitrogen permease regulator 2 Tropomyosin_1 PF12718.2 CAR28233.1 - 0.039 13.8 1.9 0.039 13.8 1.3 2.0 2 0 0 2 2 2 0 Tropomyosin like Syntaxin-6_N PF09177.6 CAR28233.1 - 0.13 12.7 2.0 2.3 8.6 0.2 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal z-alpha PF02295.12 CAR28233.1 - 0.14 11.9 0.4 0.32 10.8 0.3 1.7 1 0 0 1 1 1 0 Adenosine deaminase z-alpha domain Laminin_II PF06009.7 CAR28233.1 - 0.21 11.3 6.9 0.56 9.9 0.4 2.1 1 1 0 2 2 2 0 Laminin Domain II Prominin PF05478.6 CAR28233.1 - 1 6.8 5.6 1.3 6.4 3.9 1.0 1 0 0 1 1 1 0 Prominin Nsp1_C PF05064.8 CAR28233.1 - 3 7.5 8.7 3.2 7.4 1.1 2.1 2 0 0 2 2 2 0 Nsp1-like C-terminal region DUF948 PF06103.6 CAR28233.1 - 7.4 6.5 9.1 1.4 8.8 1.0 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) ATP12 PF07542.6 CAR28234.1 - 2.6e-31 108.1 0.0 4.3e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein Glyco_transf_34 PF05637.7 CAR28236.1 - 7.1e-53 179.5 0.0 9.5e-53 179.1 0.0 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Galactosyl_T PF01762.16 CAR28236.1 - 0.056 13.0 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 Galactosyltransferase MFS_1 PF07690.11 CAR28237.1 - 7.4e-25 87.4 18.6 1.1e-24 86.8 12.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Gon7 PF08738.5 CAR28238.1 - 3.7e-33 113.6 0.0 4.2e-33 113.4 0.0 1.1 1 0 0 1 1 1 1 Gon7 family SSB PF00436.20 CAR28239.1 - 2.1e-19 69.2 0.3 2.6e-19 69.0 0.2 1.1 1 0 0 1 1 1 1 Single-strand binding protein family p47_phox_C PF08944.6 CAR28240.1 - 0.15 12.2 0.4 0.35 11.1 0.3 1.6 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain muHD PF10291.4 CAR28241.1 - 1.8e-65 220.6 0.0 3.1e-65 219.9 0.0 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 CAR28241.1 - 0.068 13.3 0.4 0.22 11.7 0.3 1.9 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain Mannosyl_trans3 PF11051.3 CAR28242.1 - 4.6e-79 265.5 0.0 8.2e-79 264.7 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative SYCE1 PF15233.1 CAR28243.1 - 0.023 14.6 1.1 0.028 14.3 0.7 1.3 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 Thioredoxin PF00085.15 CAR28244.1 - 1.1e-27 95.7 0.0 1.2e-27 95.5 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CAR28244.1 - 7.6e-08 32.3 0.0 0.00046 20.2 0.0 2.5 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.1 CAR28244.1 - 6.3e-06 25.7 0.0 7.1e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CAR28244.1 - 8.1e-06 26.0 0.1 8.9e-05 22.6 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 CAR28244.1 - 2.5e-05 23.8 0.1 0.0033 16.9 0.1 2.1 1 1 1 2 2 2 2 Redoxin TraF PF13728.1 CAR28244.1 - 0.0024 17.4 0.0 0.0027 17.2 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein AhpC-TSA PF00578.16 CAR28244.1 - 0.0042 16.7 0.1 0.013 15.2 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family Phosducin PF02114.11 CAR28244.1 - 0.0069 15.1 0.0 0.0076 14.9 0.0 1.0 1 0 0 1 1 1 1 Phosducin Glutaredoxin PF00462.19 CAR28244.1 - 0.01 15.7 0.1 0.021 14.8 0.1 1.5 1 1 0 1 1 1 0 Glutaredoxin Thioredoxin_7 PF13899.1 CAR28244.1 - 0.14 12.1 0.1 0.24 11.4 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin-like UbiA PF01040.13 CAR28246.1 - 2.2e-31 108.9 16.7 2.9e-31 108.6 11.6 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family GHMP_kinases_N PF00288.21 CAR28247.1 - 1.1e-10 41.3 1.0 4.3e-10 39.5 0.7 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain DUF1819 PF08849.6 CAR28247.1 - 0.1 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) CagY_M PF07337.6 CAR28247.1 - 0.38 10.2 2.9 0.77 9.2 2.0 1.5 1 0 0 1 1 1 0 DC-EC Repeat WD40 PF00400.27 CAR28248.1 - 2.6e-60 198.2 13.6 2.8e-10 39.6 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 CAR28248.1 - 1.3e-30 105.4 14.2 1.3e-30 105.4 9.9 3.1 3 0 0 3 3 3 1 Tup N-terminal Nup160 PF11715.3 CAR28248.1 - 3.4e-06 25.5 2.2 0.18 9.9 0.1 3.7 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Arena_RNA_pol PF06317.6 CAR28248.1 - 7.6 2.9 11.3 10 2.5 7.8 1.0 1 0 0 1 1 1 0 Arenavirus RNA polymerase Tox-ODYAM1 PF15642.1 CAR28248.1 - 7.9 5.0 13.0 14 4.1 9.0 1.4 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Csm1 PF12539.3 CAR28249.1 - 4.2e-33 113.6 0.0 6.8e-33 113.0 0.0 1.3 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 Complex1_49kDa PF00346.14 CAR28249.1 - 0.017 14.1 0.1 0.037 13.0 0.0 1.6 2 0 0 2 2 2 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit DUF3584 PF12128.3 CAR28249.1 - 0.019 12.3 1.2 0.021 12.1 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Rootletin PF15035.1 CAR28249.1 - 0.025 14.5 4.5 0.035 14.1 3.1 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF1348 PF07080.6 CAR28249.1 - 0.031 14.0 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1348) AAA_13 PF13166.1 CAR28249.1 - 0.046 12.1 0.2 0.056 11.9 0.2 1.1 1 0 0 1 1 1 0 AAA domain DUF16 PF01519.11 CAR28249.1 - 0.061 13.5 0.9 0.11 12.7 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 Dzip-like_N PF13815.1 CAR28249.1 - 0.2 11.4 2.9 0.34 10.7 2.0 1.4 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Cluap1 PF10234.4 CAR28249.1 - 0.49 9.5 5.8 0.37 9.9 2.6 1.7 2 0 0 2 2 2 0 Clusterin-associated protein-1 zf-LYAR PF08790.6 CAR28250.1 - 9e-15 54.0 5.7 9e-15 54.0 3.9 1.6 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf-TRAF PF02176.13 CAR28250.1 - 0.076 13.4 2.4 0.13 12.6 1.7 1.5 1 0 0 1 1 1 0 TRAF-type zinc finger DUF3306 PF11748.3 CAR28250.1 - 0.086 13.4 3.6 0.14 12.8 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) A2L_zn_ribbon PF08792.5 CAR28250.1 - 0.092 12.2 4.2 0.097 12.1 0.2 2.4 2 0 0 2 2 2 0 A2L zinc ribbon domain CMV_1a PF12467.3 CAR28250.1 - 0.095 13.0 6.8 0.13 12.5 4.7 1.3 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family DUF908 PF06012.7 CAR28250.1 - 0.4 9.9 4.6 0.41 9.8 3.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Trypan_PARP PF05887.6 CAR28250.1 - 0.6 9.9 7.3 0.93 9.3 5.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) zf-C2H2_jaz PF12171.3 CAR28250.1 - 0.78 9.9 6.0 0.74 10.0 0.6 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding U79_P34 PF03064.11 CAR28250.1 - 0.83 9.1 9.6 1 8.8 6.7 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 zf-met PF12874.2 CAR28250.1 - 0.9 9.8 5.2 6.7 7.0 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Borrelia_P83 PF05262.6 CAR28250.1 - 0.95 7.6 9.6 0.99 7.5 6.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein RNHCP PF12647.2 CAR28250.1 - 1.7 8.5 5.6 2 8.2 2.3 2.0 1 1 1 2 2 2 0 RNHCP domain zf-C2H2 PF00096.21 CAR28250.1 - 1.9 8.9 6.2 1.2 9.5 0.2 2.6 2 1 0 2 2 2 0 Zinc finger, C2H2 type Ndc1_Nup PF09531.5 CAR28250.1 - 2 6.7 4.5 2.2 6.5 3.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-H2C2_2 PF13465.1 CAR28250.1 - 2.4 8.6 5.4 8.2 6.9 1.2 2.8 2 0 0 2 2 2 0 Zinc-finger double domain RR_TM4-6 PF06459.7 CAR28250.1 - 2.7 7.8 9.6 2.7 7.7 6.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2413 PF10310.4 CAR28250.1 - 3.5 6.3 10.9 4 6.1 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF4175 PF13779.1 CAR28250.1 - 3.6 5.1 8.1 3.9 5.0 5.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Cofilin_ADF PF00241.15 CAR28251.1 - 2.5e-22 79.1 0.0 4e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_1 PF00018.23 CAR28251.1 - 1.6e-16 59.3 0.5 3.8e-16 58.1 0.4 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CAR28251.1 - 7.3e-15 54.2 0.3 1.5e-14 53.3 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CAR28251.1 - 7.2e-08 31.7 0.0 1.4e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Flocculin_t3 PF13928.1 CAR28252.1 - 1.5e-25 89.0 138.6 2.2e-06 27.6 5.3 19.8 18 2 1 19 19 19 8 Flocculin type 3 repeat DUF866 PF05907.8 CAR28253.1 - 5.4e-30 104.0 1.8 3.1e-16 59.2 0.3 2.0 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF866) zf-PHD-like PF15446.1 CAR28253.1 - 0.078 12.2 2.3 0.058 12.6 0.5 1.7 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain UMP1 PF05348.6 CAR28253.1 - 0.087 12.7 0.3 0.22 11.4 0.2 1.7 1 1 1 2 2 2 0 Proteasome maturation factor UMP1 zf-BED PF02892.10 CAR28253.1 - 0.09 12.5 0.0 0.28 10.9 0.0 1.9 1 0 0 1 1 1 0 BED zinc finger Yippee-Mis18 PF03226.9 CAR28253.1 - 0.64 10.0 7.2 7.8 6.6 5.0 2.3 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SERTA PF06031.8 CAR28254.1 - 0.091 12.0 0.0 0.24 10.7 0.0 1.7 1 0 0 1 1 1 0 SERTA motif Trm112p PF03966.11 CAR28255.1 - 1.3e-21 76.6 0.2 1.8e-21 76.2 0.1 1.2 1 0 0 1 1 1 1 Trm112p-like protein ADK_lid PF05191.9 CAR28255.1 - 2.3 7.9 4.8 0.44 10.2 0.4 2.0 3 0 0 3 3 3 0 Adenylate kinase, active site lid Pkinase PF00069.20 CAR28256.1 - 4.7e-74 248.8 0.0 7.8e-74 248.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR28256.1 - 1.2e-30 106.4 0.0 1.9e-29 102.5 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR28256.1 - 2.2e-08 33.4 0.1 1.7e-05 23.9 0.0 2.7 1 1 1 2 2 2 2 Kinase-like MutS_V PF00488.16 CAR28257.1 - 1.1e-74 250.7 0.0 6.7e-74 248.2 0.0 2.1 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 CAR28257.1 - 8.4e-37 126.9 0.1 1.7e-36 125.9 0.1 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 CAR28257.1 - 2.2e-28 98.5 0.1 5.6e-28 97.2 0.1 1.8 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.13 CAR28257.1 - 2.1e-10 40.6 0.2 2.1e-10 40.6 0.2 2.8 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.12 CAR28257.1 - 0.00034 20.6 0.0 0.00034 20.6 0.0 3.2 4 0 0 4 4 4 1 MutS domain II Myc_N PF01056.13 CAR28257.1 - 0.018 14.1 9.8 0.033 13.3 6.8 1.3 1 0 0 1 1 1 0 Myc amino-terminal region DUF1270 PF06900.6 CAR28257.1 - 0.057 13.5 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1270) Not1 PF04054.10 CAR28258.1 - 1.1e-138 462.2 6.1 1.1e-138 462.2 4.2 2.6 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 CAR28258.1 - 7.7e-40 135.9 1.5 7.7e-40 135.9 1.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) Activator_LAG-3 PF11498.3 CAR28258.1 - 8.9 4.9 29.9 0.76 8.4 7.3 2.4 2 0 0 2 2 2 0 Transcriptional activator LAG-3 CDC50 PF03381.10 CAR28259.1 - 6.6e-99 330.5 1.8 7.8e-99 330.3 1.2 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Mso1_Sec1_bdg PF14475.1 CAR28260.1 - 6.8e-18 63.7 0.0 1.5e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Saccharop_dh PF03435.13 CAR28261.1 - 7e-126 420.2 0.0 7.9e-126 420.1 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 CAR28261.1 - 6.2e-08 32.8 0.1 1e-07 32.0 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 CAR28261.1 - 0.014 15.4 0.1 0.025 14.5 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding 3Beta_HSD PF01073.14 CAR28261.1 - 0.033 12.8 0.0 0.048 12.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_3 PF03447.11 CAR28261.1 - 0.046 14.1 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Y_phosphatase2 PF03162.8 CAR28262.1 - 1.2e-35 122.3 1.4 3.7e-34 117.4 1.0 2.2 1 1 0 1 1 1 1 Tyrosine phosphatase family NTF2 PF02136.15 CAR28263.1 - 9.2e-22 77.6 0.4 2e-21 76.5 0.1 1.8 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain MIP-T3 PF10243.4 CAR28263.1 - 0.0013 17.3 39.6 0.0017 16.9 27.5 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CAF1 PF04857.15 CAR28264.1 - 3.2e-53 180.7 1.6 3.2e-53 180.7 1.1 1.6 2 0 0 2 2 2 1 CAF1 family ribonuclease Spt20 PF12090.3 CAR28264.1 - 0.01 15.1 7.1 1.5 8.1 0.0 2.4 2 0 0 2 2 2 0 Spt20 family GN3L_Grn1 PF08701.6 CAR28264.1 - 0.029 14.2 3.7 0.063 13.1 2.5 1.5 1 0 0 1 1 1 0 GNL3L/Grn1 putative GTPase BAF1_ABF1 PF04684.8 CAR28264.1 - 8.9 5.0 11.6 18 4.0 8.0 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor NGP1NT PF08153.7 CAR28265.1 - 6.1e-49 165.2 2.5 1.3e-48 164.2 1.7 1.6 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 CAR28265.1 - 2.8e-20 72.4 0.1 1.1e-15 57.5 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CAR28265.1 - 5.2e-05 22.5 0.1 0.00021 20.6 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CAR28265.1 - 0.0015 18.3 4.6 0.29 10.9 0.0 3.7 3 1 1 4 4 4 2 Dynamin family DUF258 PF03193.11 CAR28265.1 - 0.0017 17.6 0.0 0.0031 16.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arf PF00025.16 CAR28265.1 - 0.0043 16.3 0.1 0.13 11.5 0.0 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family SusD-like_3 PF14322.1 CAR28265.1 - 0.0055 16.7 0.1 0.011 15.7 0.1 1.6 1 0 0 1 1 1 1 Starch-binding associating with outer membrane GTP_EFTU PF00009.22 CAR28265.1 - 0.011 15.2 0.2 2.4 7.5 0.0 3.3 1 1 1 3 3 3 0 Elongation factor Tu GTP binding domain RRM_5 PF13893.1 CAR28266.1 - 0.0013 18.5 0.0 0.0094 15.7 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAR28266.1 - 0.0018 17.8 0.0 0.25 11.0 0.0 2.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHD_3 PF13922.1 CAR28266.1 - 1.5 9.1 0.0 1.5 9.1 0.0 3.2 3 2 0 3 3 3 0 PHD domain of transcriptional enhancer, Asx Cwf_Cwc_15 PF04889.7 CAR28266.1 - 5.7 6.5 42.6 3 7.4 6.2 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Cytochrome-c551 PF10643.4 CAR28266.1 - 6.9 5.8 6.9 1.9 7.6 1.0 2.1 2 0 0 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 ABC2_membrane PF01061.19 CAR28267.1 - 3.7e-86 287.6 58.0 1.8e-44 151.4 16.4 2.9 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 CAR28267.1 - 1.7e-40 136.8 0.9 1.1e-35 121.3 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 CAR28267.1 - 2.4e-40 138.0 0.0 8.5e-19 68.2 0.0 3.1 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.1 CAR28267.1 - 3.4e-22 78.3 0.1 9.4e-22 76.9 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 CAR28267.1 - 3.4e-08 33.1 0.2 5.9e-05 22.5 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 CAR28267.1 - 5.3e-07 29.8 0.1 5.3e-05 23.2 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 CAR28267.1 - 1.1e-05 24.6 0.0 0.00085 18.5 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 CAR28267.1 - 8.4e-05 22.0 3.0 0.015 14.7 0.2 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 CAR28267.1 - 0.00014 21.7 0.0 0.053 13.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CAR28267.1 - 0.00018 21.7 0.0 0.13 12.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CAR28267.1 - 0.00033 20.1 0.5 0.0047 16.4 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_19 PF13245.1 CAR28267.1 - 0.0004 20.0 0.5 1.2 8.9 0.0 2.5 2 0 0 2 2 2 2 Part of AAA domain AAA_21 PF13304.1 CAR28267.1 - 0.0006 19.8 0.3 0.053 13.4 0.0 3.6 4 0 0 4 4 4 1 AAA domain SMC_N PF02463.14 CAR28267.1 - 0.00063 19.0 0.0 0.041 13.1 0.0 2.7 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 CAR28267.1 - 0.001 19.2 0.0 0.38 10.9 0.0 3.1 3 0 0 3 3 2 1 AAA domain NACHT PF05729.7 CAR28267.1 - 0.0011 18.6 0.1 1.7 8.2 0.0 2.7 2 0 0 2 2 2 2 NACHT domain UPF0079 PF02367.12 CAR28267.1 - 0.005 16.4 0.5 0.73 9.4 0.1 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 CAR28267.1 - 0.0087 16.0 2.2 0.13 12.2 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 CAR28267.1 - 0.012 16.0 2.0 0.14 12.4 0.1 2.9 2 1 1 3 3 3 0 AAA domain AAA_10 PF12846.2 CAR28267.1 - 0.026 13.9 1.0 17 4.7 0.1 3.7 4 0 0 4 4 4 0 AAA-like domain AAA_17 PF13207.1 CAR28267.1 - 0.029 15.1 0.0 1.1 10.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 CAR28267.1 - 0.032 14.4 0.1 9.2 6.4 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 CAR28267.1 - 0.04 13.6 0.0 1.6 8.3 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase AAA_30 PF13604.1 CAR28267.1 - 0.11 12.1 0.3 5.8 6.4 0.1 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 CAR28267.1 - 0.11 11.9 0.0 6.6 6.1 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein PduV-EutP PF10662.4 CAR28267.1 - 0.11 11.9 0.7 2.3 7.7 0.2 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 CAR28267.1 - 0.22 11.2 0.5 29 4.3 0.1 2.8 3 0 0 3 3 3 0 NTPase AAA_24 PF13479.1 CAR28267.1 - 0.84 9.1 2.9 34 3.9 0.1 3.0 3 0 0 3 3 3 0 AAA domain Zip PF02535.17 CAR28268.1 - 1e-52 179.1 0.1 1.2e-52 178.9 0.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter SSF PF00474.12 CAR28269.1 - 2e-21 76.1 21.8 3e-21 75.5 15.1 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family FMO-like PF00743.14 CAR28270.1 - 3.6e-30 104.6 0.5 7.1e-18 64.0 0.0 2.8 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 CAR28270.1 - 8.1e-15 55.4 0.0 6.3e-09 36.1 0.0 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CAR28270.1 - 7.1e-06 26.0 0.0 0.072 12.9 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CAR28270.1 - 7.7e-06 25.7 0.0 0.034 13.9 0.0 4.1 4 1 0 4 4 4 2 FAD-NAD(P)-binding DAO PF01266.19 CAR28270.1 - 1.2e-05 24.3 0.0 0.16 10.8 0.0 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 CAR28270.1 - 2.2e-05 23.5 0.0 0.0021 17.0 0.0 3.0 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 CAR28270.1 - 0.029 14.3 0.2 0.69 9.9 0.0 3.0 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 CAR28270.1 - 0.071 11.5 0.0 2.8 6.2 0.0 2.6 2 1 1 3 3 3 0 HI0933-like protein Bac_luciferase PF00296.15 CAR28271.1 - 7.2e-53 179.6 0.0 1.1e-52 179.0 0.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase ADH_zinc_N PF00107.21 CAR28272.1 - 1e-07 31.5 0.0 1.7e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CAR28272.1 - 2.5e-05 23.9 0.0 5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 CAR28272.1 - 0.012 16.5 0.0 0.031 15.1 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Sugar_tr PF00083.19 CAR28273.1 - 2e-79 267.3 23.9 2.5e-79 266.9 16.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR28273.1 - 1.4e-24 86.4 32.3 1.4e-24 86.4 22.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 CAR28273.1 - 0.052 11.7 9.0 0.017 13.3 1.9 2.3 2 1 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) AA_permease PF00324.16 CAR28274.1 - 5.4e-98 328.4 51.6 6.6e-98 328.1 35.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CAR28274.1 - 1.7e-28 99.3 54.8 2e-28 99.1 38.0 1.1 1 0 0 1 1 1 1 Amino acid permease lci PF12197.3 CAR28274.1 - 0.04 13.4 0.8 0.092 12.3 0.5 1.6 1 0 0 1 1 1 0 Bacillus cereus group antimicrobial protein Acetyltransf_3 PF13302.1 CAR28275.1 - 1e-17 64.6 0.0 1.5e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CAR28275.1 - 1.8e-07 31.2 0.0 2.3e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CAR28275.1 - 1.3e-05 25.1 0.0 2.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 CAR28275.1 - 0.0025 17.6 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3873 PF12989.2 CAR28275.1 - 0.053 13.6 0.1 0.1 12.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) AA_permease PF00324.16 CAR28276.1 - 1.5e-109 366.4 35.8 1.7e-109 366.2 24.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CAR28276.1 - 1.7e-36 125.6 36.5 2.2e-36 125.3 25.3 1.1 1 0 0 1 1 1 1 Amino acid permease TrbC PF04956.8 CAR28276.1 - 0.37 10.8 17.2 2.2 8.3 0.1 4.4 4 0 0 4 4 4 0 TrbC/VIRB2 family OPT PF03169.10 CAR28277.1 - 9.6e-143 476.8 45.6 1.1e-142 476.6 31.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4191 PF13829.1 CAR28277.1 - 0.68 9.0 2.9 1.5 7.8 2.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Flocculin PF00624.13 CAR28278.1 - 2.7e-269 868.9 834.9 7.6e-11 41.6 10.6 38.4 38 1 1 39 39 39 32 Flocculin repeat Lambda_tail_I PF06805.7 CAR28278.1 - 3.4e-21 74.8 0.0 3.2e+02 1.2 0.0 25.1 31 0 0 31 31 31 0 Bacteriophage lambda tail assembly protein I PA14_2 PF10528.4 CAR28278.1 - 4.5e-13 49.1 1.9 4.5e-13 49.1 1.3 5.2 4 0 0 4 4 4 1 GLEYA domain Sensor PF13796.1 CAR28278.1 - 0.011 15.3 6.0 82 2.7 0.0 6.8 6 1 1 7 7 7 0 Putative sensor Thioesterase PF00975.15 CAR28278.1 - 0.015 15.4 0.9 8.6e+02 -0.1 0.0 7.3 2 1 6 10 10 10 0 Thioesterase domain AA_permease_2 PF13520.1 CAR28279.1 - 2.4e-49 168.0 51.9 3.1e-49 167.6 36.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CAR28279.1 - 4.3e-18 64.9 42.8 5.7e-18 64.5 29.7 1.1 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 CAR28280.1 - 2.5e-16 59.3 16.2 3.7e-16 58.7 11.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Nucleoside_tran PF01733.13 CAR28280.1 - 0.18 10.9 7.7 0.95 8.5 0.3 2.6 2 1 1 3 3 3 0 Nucleoside transporter TauD PF02668.11 CAR28281.1 - 9.8e-53 179.4 0.5 1.4e-52 178.8 0.3 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family RrnaAD PF00398.15 CAR28282.1 - 4.3e-62 209.5 0.0 5e-62 209.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 CAR28282.1 - 9.3e-10 38.5 0.0 1.4e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR28282.1 - 1.4e-05 25.5 0.0 2.3e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CAR28282.1 - 0.00046 19.7 0.0 0.00069 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 CAR28282.1 - 0.00069 18.7 0.0 0.0022 17.1 0.0 1.7 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 CAR28282.1 - 0.0017 17.7 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 CAR28282.1 - 0.0021 17.8 0.0 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 CAR28282.1 - 0.0026 16.7 0.0 0.0046 15.8 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_31 PF13847.1 CAR28282.1 - 0.0083 15.7 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAR28282.1 - 0.02 15.3 0.0 0.041 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 CAR28282.1 - 0.047 12.7 0.0 0.11 11.5 0.0 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.12 CAR28282.1 - 0.058 12.7 0.0 0.082 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_2 PF00891.13 CAR28282.1 - 0.079 12.1 0.1 0.21 10.7 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase PI-PLC-X PF00388.14 CAR28284.1 - 1.2e-46 157.7 0.0 3e-46 156.4 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 CAR28284.1 - 5e-37 126.4 1.1 1.9e-36 124.6 0.1 2.4 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_7 PF13499.1 CAR28284.1 - 3.4e-09 36.7 2.5 4e-05 23.6 0.3 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_like PF09279.6 CAR28284.1 - 4.5e-08 32.9 0.3 4.5e-08 32.9 0.2 2.1 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_1 PF00036.27 CAR28284.1 - 2.7e-07 29.3 1.9 3e-06 26.1 0.1 3.1 3 0 0 3 3 3 1 EF hand C2 PF00168.25 CAR28284.1 - 5.6e-05 22.8 0.1 0.00029 20.6 0.0 2.1 2 0 0 2 2 2 1 C2 domain EF-hand_5 PF13202.1 CAR28284.1 - 7.2e-05 21.9 0.3 0.00019 20.6 0.2 1.8 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 CAR28284.1 - 7.9e-05 22.2 0.9 0.081 12.5 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CAR28284.1 - 0.0027 17.4 4.2 0.0042 16.8 0.1 3.2 4 0 0 4 4 4 1 EF-hand domain EF-hand_10 PF14788.1 CAR28284.1 - 0.28 10.8 4.5 0.11 12.2 0.2 2.5 3 0 0 3 3 3 0 EF hand KAR9 PF08580.5 CAR28285.1 - 8.5e-98 328.3 18.7 7.1e-97 325.3 11.7 2.0 1 1 0 2 2 2 2 Yeast cortical protein KAR9 UBN2 PF14223.1 CAR28285.1 - 0.19 11.4 6.2 0.053 13.3 1.2 2.3 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type RICH PF05062.7 CAR28285.1 - 3.1 8.0 9.3 0.79 9.8 0.1 2.7 2 0 0 2 2 2 0 RICH domain ABC_membrane PF00664.18 CAR28286.1 - 1.1e-53 182.4 3.9 1.4e-53 182.0 2.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 CAR28286.1 - 6.9e-34 117.0 0.0 2.2e-33 115.4 0.0 1.9 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 CAR28286.1 - 0.00086 18.6 0.0 0.028 13.6 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CAR28286.1 - 0.0031 17.5 0.0 0.0086 16.0 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.4 CAR28286.1 - 0.0048 15.5 0.1 0.0099 14.5 0.0 1.5 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_25 PF13481.1 CAR28286.1 - 0.0078 15.6 0.0 0.04 13.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CAR28286.1 - 0.0088 15.5 0.0 0.035 13.6 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 CAR28286.1 - 0.0092 16.8 0.0 0.018 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CAR28286.1 - 0.017 14.5 0.0 0.084 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain IstB_IS21 PF01695.12 CAR28286.1 - 0.022 14.1 0.0 0.47 9.8 0.0 2.5 2 1 1 3 3 3 0 IstB-like ATP binding protein AAA_22 PF13401.1 CAR28286.1 - 0.029 14.5 0.0 0.27 11.3 0.0 2.4 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 CAR28286.1 - 0.044 13.9 0.0 0.31 11.2 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.1 CAR28286.1 - 0.045 13.7 0.0 17 5.2 0.0 2.4 1 1 0 2 2 2 0 AAA domain AAA_5 PF07728.9 CAR28286.1 - 0.048 13.3 0.0 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATP-synt_Eps PF04627.8 CAR28287.1 - 9.3e-22 76.3 1.1 1e-21 76.1 0.7 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain DNA_pol_phi PF04931.8 CAR28288.1 - 2e-134 449.2 29.8 2.9e-134 448.7 20.7 1.2 1 0 0 1 1 1 1 DNA polymerase phi DUF664 PF04978.7 CAR28288.1 - 2.7 8.1 8.2 1.1 9.5 2.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF664) WD40 PF00400.27 CAR28289.1 - 3.1e-25 87.0 0.0 8.7e-07 28.5 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CAR28289.1 - 6.2e-23 80.4 0.3 1.2e-22 79.6 0.2 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex DUF3312 PF11768.3 CAR28289.1 - 0.098 10.8 0.0 1.1 7.3 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3312) Kelch_3 PF13415.1 CAR28290.1 - 3e-28 97.2 12.8 1e-09 38.2 0.1 6.8 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.1 CAR28290.1 - 4.4e-28 96.8 10.0 7.4e-06 25.6 0.7 6.8 5 2 1 6 6 6 5 Galactose oxidase, central domain DUF4110 PF13422.1 CAR28290.1 - 7.2e-26 89.8 0.1 7.2e-26 89.8 0.1 5.0 3 3 3 6 6 6 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.1 CAR28290.1 - 1.2e-20 72.7 10.7 7.9e-06 25.8 0.1 6.3 5 1 1 6 6 6 5 Kelch motif Kelch_5 PF13854.1 CAR28290.1 - 3.1e-12 46.1 1.4 0.0026 17.6 0.0 5.8 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.20 CAR28290.1 - 1.1e-10 40.8 16.9 5.2e-05 22.6 0.1 5.7 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 CAR28290.1 - 4.4e-09 35.7 15.2 0.068 12.9 0.3 5.4 6 0 0 6 6 6 4 Kelch motif BUD22 PF09073.5 CAR28290.1 - 1.5 7.8 42.2 0.2 10.6 7.4 3.1 3 0 0 3 3 3 0 BUD22 PGM_PMM_I PF02878.11 CAR28291.1 - 1.1e-14 54.0 0.0 7.6e-08 31.9 0.0 2.5 1 1 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 CAR28291.1 - 2.3e-11 43.9 0.0 9.8e-11 41.9 0.0 2.1 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 CAR28291.1 - 8.5e-10 38.5 0.2 2.2e-09 37.1 0.2 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RNase_Zc3h12a_2 PF14626.1 CAR28291.1 - 0.097 12.5 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain Mitochondr_Som1 PF11093.3 CAR28292.1 - 5.4e-21 74.1 0.6 7e-21 73.8 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial export protein Som1 HIM1 PF08732.5 CAR28293.1 - 1.7e-86 290.2 0.1 2e-86 290.0 0.1 1.0 1 0 0 1 1 1 1 HIM1 NAD_binding_10 PF13460.1 CAR28293.1 - 0.02 14.8 0.0 7.6 6.4 0.0 2.4 2 0 0 2 2 2 0 NADH(P)-binding BOP1NT PF08145.7 CAR28294.1 - 3.3e-104 348.2 6.5 7.1e-104 347.1 4.5 1.6 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 CAR28294.1 - 1.5e-26 91.2 5.3 3.8e-11 42.4 0.2 6.9 7 0 0 7 7 7 3 WD domain, G-beta repeat Swi3 PF07962.7 CAR28295.1 - 2.3e-24 84.8 0.2 3.8e-24 84.1 0.1 1.4 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Nucleoporin_FG PF13634.1 CAR28296.1 - 7.6e-76 251.6 424.7 5.1e-18 65.3 28.4 11.6 3 1 9 12 12 12 10 Nucleoporin FG repeat region Nucleoporin2 PF04096.9 CAR28296.1 - 2.2e-44 150.6 0.0 4.8e-44 149.6 0.0 1.6 1 0 0 1 1 1 1 Nucleoporin autopeptidase PWWP PF00855.12 CAR28297.1 - 9.9e-23 80.1 1.6 9.9e-23 80.1 1.1 2.3 2 1 0 2 2 2 1 PWWP domain MIP-T3 PF10243.4 CAR28297.1 - 0.031 12.7 16.8 0.042 12.3 11.6 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 YL1 PF05764.8 CAR28297.1 - 0.26 10.8 23.7 0.53 9.8 16.4 1.5 1 0 0 1 1 1 0 YL1 nuclear protein Sec62 PF03839.11 CAR28297.1 - 0.62 9.4 7.6 2.3 7.5 5.3 2.0 1 0 0 1 1 1 0 Translocation protein Sec62 GAGA_bind PF06217.7 CAR28297.1 - 2.1 8.2 7.6 3.1 7.6 5.3 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DDHD PF02862.12 CAR28297.1 - 2.3 7.9 7.2 4.4 7.0 5.0 1.5 1 0 0 1 1 1 0 DDHD domain SRF-TF PF00319.13 CAR28298.1 - 2.2e-25 87.5 0.3 3.1e-25 87.1 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) SRF-TF PF00319.13 CAR28299.1 - 6.6e-24 82.8 0.1 6.6e-24 82.8 0.1 1.4 2 0 0 2 2 2 1 SRF-type transcription factor (DNA-binding and dimerisation domain) NDK PF00334.14 CAR28300.1 - 5.8e-55 184.7 0.0 6.6e-55 184.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Aldo_ket_red PF00248.16 CAR28302.1 - 2.5e-47 161.0 0.0 3.1e-47 160.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Bap31 PF05529.7 CAR28303.1 - 4.6e-48 163.2 0.1 5.4e-48 163.0 0.1 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like EzrA PF06160.7 CAR28303.1 - 0.01 14.0 0.3 0.015 13.4 0.2 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Sec2p PF06428.6 CAR28303.1 - 0.039 13.8 0.7 0.062 13.1 0.5 1.3 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Fib_alpha PF08702.5 CAR28303.1 - 0.058 13.5 1.2 0.1 12.6 0.8 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family RBD-FIP PF09457.5 CAR28303.1 - 0.078 12.7 1.7 0.15 11.9 1.2 1.4 1 0 0 1 1 1 0 FIP domain IL6 PF00489.12 CAR28303.1 - 0.11 12.0 0.7 0.71 9.4 0.2 2.2 3 0 0 3 3 3 0 Interleukin-6/G-CSF/MGF family PC4 PF02229.11 CAR28304.1 - 3.2e-20 71.0 0.0 6.2e-20 70.1 0.0 1.5 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) CorA PF01544.13 CAR28305.1 - 3.4e-38 131.3 5.9 3.8e-20 72.1 0.2 3.3 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein Herpes_LP PF03363.8 CAR28305.1 - 0.0012 18.4 4.6 0.0042 16.6 3.2 1.9 1 0 0 1 1 1 1 Herpesvirus leader protein DUF3961 PF13106.1 CAR28305.1 - 0.12 11.9 4.1 0.28 10.7 2.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) Pex14_N PF04695.8 CAR28305.1 - 4.7 7.2 7.7 5.4 7.0 0.1 3.9 4 0 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region HMA PF00403.21 CAR28306.1 - 3.4e-13 49.5 0.0 7.6e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.15 CAR28306.1 - 1.1e-08 35.3 0.0 3e-08 33.9 0.0 1.7 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) zf-C2H2 PF00096.21 CAR28308.1 - 1.3e-10 40.9 13.7 6.4e-06 26.2 2.7 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CAR28308.1 - 6.5e-09 35.5 12.5 7.2e-05 22.8 2.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CAR28308.1 - 1.7e-08 34.3 19.0 9.5e-07 28.8 1.8 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-BED PF02892.10 CAR28308.1 - 1.1e-05 25.0 4.3 0.026 14.2 0.4 2.5 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_jaz PF12171.3 CAR28308.1 - 4.3e-05 23.5 11.1 0.028 14.5 0.5 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CAR28308.1 - 0.031 14.4 7.8 1.1 9.5 1.4 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type GAGA PF09237.6 CAR28308.1 - 0.036 13.6 1.8 0.72 9.4 0.1 2.5 1 1 1 2 2 2 0 GAGA factor zf-C2H2_2 PF12756.2 CAR28308.1 - 0.058 13.5 7.6 0.85 9.7 1.4 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 CAR28308.1 - 0.074 12.9 10.1 1.1 9.2 1.8 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.7 CAR28308.1 - 0.16 12.1 4.3 0.28 11.3 3.0 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF629 PF04780.7 CAR28308.1 - 0.58 8.6 8.6 0.17 10.3 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF629) PAT1 PF09770.4 CAR28308.1 - 3.9 5.5 12.1 6.5 4.8 8.4 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pkinase PF00069.20 CAR28309.1 - 4.8e-42 143.9 0.0 1.3e-41 142.5 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR28309.1 - 1.5e-21 76.6 0.0 2.9e-17 62.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CAR28309.1 - 0.0015 17.5 0.0 0.0082 15.1 0.0 1.9 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CAR28309.1 - 0.0051 16.5 0.0 0.0082 15.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Rhodanese PF00581.15 CAR28310.1 - 2.1e-10 40.9 0.0 4.6e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Peptidase_S24 PF00717.18 CAR28311.1 - 5.9e-08 32.2 0.0 1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 CAR28311.1 - 0.018 14.5 0.0 0.064 12.7 0.0 1.8 1 1 1 2 2 2 0 Signal peptidase, peptidase S26 DUF4137 PF13593.1 CAR28312.1 - 1.5e-110 369.1 12.2 1.8e-110 368.9 8.5 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Actin PF00022.14 CAR28313.1 - 2.9e-18 65.4 0.0 2.3e-17 62.5 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CAR28313.1 - 0.00034 19.3 0.2 0.14 10.6 0.1 2.9 3 0 0 3 3 3 2 MreB/Mbl protein FtsA PF14450.1 CAR28313.1 - 0.0019 18.0 0.1 0.0042 16.9 0.0 1.6 1 0 0 1 1 1 1 Cell division protein FtsA BBS2_N PF14781.1 CAR28313.1 - 0.032 13.8 0.4 0.29 10.7 0.0 2.4 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal Histone PF00125.19 CAR28314.1 - 2.2e-26 91.7 0.7 2.2e-26 91.7 0.5 2.2 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CAR28314.1 - 0.014 15.5 0.1 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 Kinetochore component CENP-S FCH PF00611.18 CAR28315.1 - 2.4e-19 69.3 0.9 1.4e-18 66.8 0.1 2.8 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 CAR28315.1 - 0.00018 21.0 0.1 0.00039 19.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CAR28315.1 - 0.016 14.5 0.0 0.032 13.6 0.0 1.5 1 0 0 1 1 1 0 SH3 domain DUF3812 PF12757.2 CAR28316.1 - 6.5e-31 106.9 3.2 6.5e-31 106.9 2.2 5.3 3 2 0 3 3 3 1 Protein of unknown function (DUF3812) DUF1664 PF07889.7 CAR28316.1 - 8.4 6.2 16.2 7 6.4 4.0 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Frag1 PF10277.4 CAR28317.1 - 1.6e-70 236.9 21.0 1.9e-70 236.6 14.5 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DASH_Ask1 PF08655.5 CAR28318.1 - 7.6e-21 73.7 0.0 1.2e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 Lyase_aromatic PF00221.14 CAR28318.1 - 0.033 12.6 0.0 0.045 12.1 0.0 1.1 1 0 0 1 1 1 0 Aromatic amino acid lyase ECH_C PF13766.1 CAR28319.1 - 5.9e-26 90.9 0.0 1.1e-25 90.0 0.0 1.5 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 CAR28319.1 - 2.7e-25 88.8 0.0 4.7e-25 88.1 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family UCH PF00443.24 CAR28320.1 - 2.2e-44 151.6 0.0 4.6e-44 150.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CAR28320.1 - 2.8e-21 76.2 0.0 2.5e-20 73.1 0.0 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CAR28320.1 - 2.5e-19 69.1 6.1 2.5e-19 69.1 4.2 3.2 3 1 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 CAR28320.1 - 1.5e-10 40.5 0.1 0.00029 20.5 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain zf-Mss51 PF13824.1 CAR28320.1 - 0.0063 16.3 3.3 5.8 6.8 1.0 3.9 3 0 0 3 3 3 1 Zinc-finger of mitochondrial splicing suppressor 51 Prismane PF03063.15 CAR28321.1 - 0.25 9.6 2.4 0.32 9.3 1.7 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family KfrA_N PF11740.3 CAR28321.1 - 0.45 10.9 8.9 5.6 7.4 0.6 3.2 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term FlaC_arch PF05377.6 CAR28321.1 - 0.65 9.9 14.4 2.2 8.2 0.3 3.9 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DAHP_synth_1 PF00793.15 CAR28322.1 - 1.2e-101 339.0 0.0 1.4e-101 338.7 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Cellulase PF00150.13 CAR28323.1 - 2.1e-13 50.1 3.4 2.1e-13 50.1 2.4 2.0 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Ribosomal_L7Ae PF01248.21 CAR28324.1 - 5.2e-28 96.4 0.1 8.8e-28 95.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CAR28324.1 - 0.00038 20.3 0.1 0.00073 19.4 0.0 1.4 2 0 0 2 2 2 1 RNase P subunit Pop3 DUF3692 PF12469.3 CAR28324.1 - 0.17 12.1 1.5 0.63 10.2 0.7 1.9 1 1 1 2 2 2 0 CRISPR-associated protein Adaptin_N PF01602.15 CAR28327.1 - 1.2e-101 340.6 9.4 1.9e-101 340.0 6.5 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 CAR28327.1 - 8.4e-60 200.1 0.0 2.1e-59 198.8 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 CAR28327.1 - 4.7e-53 178.6 0.2 4.7e-53 178.6 0.1 2.4 2 0 0 2 2 2 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 CAR28327.1 - 3.3e-08 33.6 2.8 0.011 15.9 0.0 4.7 2 1 2 4 4 4 3 HEAT repeats HEAT PF02985.17 CAR28327.1 - 0.017 15.1 1.0 6.5 7.1 0.0 4.8 4 1 1 5 5 5 0 HEAT repeat TM1586_NiRdase PF14512.1 CAR28327.1 - 0.056 12.6 0.1 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative TM nitroreductase Cnd1 PF12717.2 CAR28327.1 - 0.095 12.5 9.1 0.82 9.4 0.1 3.8 3 2 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 CAR28327.1 - 0.2 12.1 3.5 11 6.6 0.0 5.0 4 2 1 5 5 5 0 HEAT-like repeat Ribosomal_S2 PF00318.15 CAR28328.1 - 3.5e-39 134.1 0.0 4e-21 75.2 0.0 2.3 1 1 1 2 2 2 2 Ribosomal protein S2 Ferric_reduct PF01794.14 CAR28329.1 - 4.2e-18 65.6 11.5 4.2e-18 65.6 7.9 2.1 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 CAR28329.1 - 0.0026 17.6 0.0 0.0056 16.5 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain AATase PF07247.7 CAR28330.1 - 6.1e-64 216.3 0.9 9.9e-64 215.6 0.6 1.2 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 CAR28330.1 - 3.1e-08 32.8 0.2 9.6e-05 21.3 0.0 2.2 2 0 0 2 2 2 2 Condensation domain WES_acyltransf PF03007.11 CAR28330.1 - 0.066 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain zf-ZPR1 PF03367.8 CAR28331.1 - 1.5e-118 391.5 2.4 8e-59 197.3 0.1 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain DUF2294 PF10057.4 CAR28331.1 - 0.088 12.4 0.4 0.25 10.9 0.3 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2294) UPF0547 PF10571.4 CAR28331.1 - 0.51 10.0 5.7 9.1 6.0 0.0 3.0 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 DUF3716 PF12511.3 CAR28331.1 - 0.59 9.7 3.5 8 6.1 1.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) OrfB_Zn_ribbon PF07282.6 CAR28331.1 - 1 9.0 4.1 15 5.3 0.0 2.9 3 0 0 3 3 3 0 Putative transposase DNA-binding domain DNA_RNApol_7kD PF03604.8 CAR28331.1 - 1.1 8.7 4.5 24 4.4 0.1 3.5 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Zn-ribbon_8 PF09723.5 CAR28331.1 - 7.2 6.6 8.7 5.9 6.9 0.1 3.9 4 0 0 4 4 4 0 Zinc ribbon domain MMR_HSR1_C PF08438.5 CAR28332.1 - 1.6e-31 108.7 0.0 2.7e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 CAR28332.1 - 4.9e-17 61.9 0.0 9.9e-17 60.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CAR28332.1 - 4.6e-06 25.9 0.0 4.3e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 CAR28332.1 - 0.0021 17.4 0.0 2.5 7.4 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CAR28332.1 - 0.016 15.0 0.2 0.077 12.8 0.1 2.1 3 0 0 3 3 3 0 Dynamin family AAA_10 PF12846.2 CAR28332.1 - 0.065 12.6 0.0 0.14 11.5 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain AAA_17 PF13207.1 CAR28332.1 - 0.099 13.4 1.2 0.66 10.8 0.6 2.5 2 1 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 CAR28332.1 - 0.11 12.0 0.1 8.3 5.8 0.0 2.6 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein ArgK PF03308.11 CAR28332.1 - 0.12 11.1 1.1 0.32 9.7 0.0 2.2 3 0 0 3 3 3 0 ArgK protein ABC_tran PF00005.22 CAR28332.1 - 0.15 12.3 0.0 0.54 10.5 0.0 1.9 2 0 0 2 2 2 0 ABC transporter TPP_enzyme_M PF00205.17 CAR28333.1 - 4.8e-36 123.5 0.0 2.6e-35 121.1 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.13 CAR28333.1 - 2e-35 121.8 0.1 3.1e-35 121.1 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 CAR28333.1 - 1.3e-13 50.7 0.0 2.5e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain IncA PF04156.9 CAR28334.1 - 0.00045 19.8 12.6 0.00045 19.8 8.7 3.0 3 0 0 3 3 3 1 IncA protein HEAT PF02985.17 CAR28334.1 - 0.00052 19.8 1.6 0.85 9.8 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat Mod_r PF07200.8 CAR28334.1 - 0.78 9.6 23.9 0.43 10.4 11.6 3.0 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein APG6 PF04111.7 CAR28334.1 - 1.5 7.8 15.6 5.2 6.0 10.8 1.9 1 0 0 1 1 1 0 Autophagy protein Apg6 ATG16 PF08614.6 CAR28334.1 - 4.7 6.9 27.2 0.89 9.3 15.4 2.5 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Thioredoxin PF00085.15 CAR28335.1 - 3e-31 107.1 0.4 3.3e-31 107.0 0.3 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CAR28335.1 - 4.2e-09 36.6 0.3 6e-08 32.8 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CAR28335.1 - 1.2e-07 31.6 0.2 3.7e-07 30.1 0.2 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 CAR28335.1 - 4.3e-07 29.5 0.0 4.6e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 CAR28335.1 - 4.2e-06 26.3 0.4 9.7e-06 25.1 0.3 1.6 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 CAR28335.1 - 5.2e-06 26.1 0.1 6.1e-06 25.9 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family DIM1 PF02966.11 CAR28335.1 - 0.0012 18.4 0.0 0.0013 18.2 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_4 PF13462.1 CAR28335.1 - 0.0048 16.9 0.4 0.21 11.6 0.1 2.0 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_7 PF13899.1 CAR28335.1 - 0.018 15.0 0.2 0.034 14.1 0.1 1.7 1 1 0 1 1 1 0 Thioredoxin-like TraF PF13728.1 CAR28335.1 - 0.027 13.9 0.1 0.036 13.5 0.1 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Hydrolase PF00702.21 CAR28336.1 - 3.8e-15 56.8 0.0 2.2e-13 51.1 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CAR28336.1 - 1.1e-14 55.0 0.0 1.5e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CAR28336.1 - 7e-11 42.1 0.3 1.8e-09 37.5 0.0 2.6 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CAR28336.1 - 2.2e-08 34.5 0.0 4.2e-07 30.3 0.0 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase S6PP PF05116.8 CAR28336.1 - 0.00035 19.9 0.5 0.0024 17.2 0.0 2.3 3 0 0 3 3 3 1 Sucrose-6F-phosphate phosphohydrolase Acid_PPase PF12689.2 CAR28336.1 - 0.011 15.3 0.0 0.051 13.2 0.0 2.0 1 1 0 1 1 1 0 Acid Phosphatase DUF2608 PF11019.3 CAR28336.1 - 0.014 14.4 0.0 0.026 13.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) DUF705 PF05152.7 CAR28336.1 - 0.015 14.3 0.5 0.019 13.9 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) Put_Phosphatase PF06888.7 CAR28336.1 - 0.029 13.5 0.1 1.2 8.2 0.0 2.2 2 0 0 2 2 2 0 Putative Phosphatase LysR_substrate PF03466.15 CAR28336.1 - 0.087 11.9 0.0 0.55 9.2 0.0 2.1 2 0 0 2 2 2 0 LysR substrate binding domain Yip1 PF04893.12 CAR28337.1 - 2.1e-13 50.1 13.6 3.5e-13 49.4 9.4 1.4 1 0 0 1 1 1 1 Yip1 domain tRNA-synt_1g PF09334.6 CAR28338.1 - 4.9e-108 361.2 1.7 9e-108 360.3 1.2 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CAR28338.1 - 8.2e-24 83.5 0.1 2e-09 36.0 0.0 3.5 2 1 2 4 4 4 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 CAR28338.1 - 7e-07 28.6 0.2 0.0047 16.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 CAR28338.1 - 0.0021 17.8 0.0 0.0049 16.6 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA DNA_pol_E_B PF04042.11 CAR28339.1 - 4e-44 150.3 1.0 8e-44 149.3 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B PS_Dcarbxylase PF02666.10 CAR28340.1 - 6.5e-53 179.0 0.0 1.1e-52 178.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 CAR28340.1 - 1.5e-11 43.9 1.1 7.5e-10 38.5 0.1 2.6 2 0 0 2 2 2 2 C2 domain zf-C2HC5 PF06221.8 CAR28341.1 - 9.6e-19 66.8 6.6 1.8e-18 65.9 4.6 1.5 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Zn_clus PF00172.13 CAR28342.1 - 4.1e-06 26.5 13.6 9.2e-06 25.4 9.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 CAR28342.1 - 0.00057 19.6 0.6 0.0025 17.5 0.0 2.1 2 0 0 2 2 2 1 PAS fold IncA PF04156.9 CAR28342.1 - 0.0044 16.6 4.3 0.0077 15.8 3.0 1.5 1 0 0 1 1 1 1 IncA protein PAS_9 PF13426.1 CAR28342.1 - 0.046 14.0 0.5 0.2 12.0 0.0 2.3 2 0 0 2 2 2 0 PAS domain DUF4337 PF14235.1 CAR28342.1 - 0.075 12.8 5.4 0.17 11.7 3.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) MRC1 PF09444.5 CAR28342.1 - 0.22 11.8 0.1 0.22 11.8 0.1 2.7 3 0 0 3 3 3 0 MRC1-like domain DUF3573 PF12097.3 CAR28342.1 - 0.31 9.6 3.3 0.56 8.7 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Synaptobrevin PF00957.16 CAR28342.1 - 1.1 8.8 7.1 2.8 7.5 4.9 1.6 1 0 0 1 1 1 0 Synaptobrevin EAP30 PF04157.11 CAR28342.1 - 2.3 7.2 9.2 6.5 5.8 6.4 1.7 1 0 0 1 1 1 0 EAP30/Vps36 family DEAD PF00270.24 CAR28343.1 - 2e-37 128.2 0.0 3.6e-37 127.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR28343.1 - 1.6e-18 66.3 0.0 3.4e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CAR28343.1 - 4.5e-17 61.3 0.1 1.2e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 CAR28343.1 - 0.00018 21.3 1.7 0.0014 18.5 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit P53_TAD PF08563.6 CAR28343.1 - 0.06 12.4 0.4 0.13 11.3 0.3 1.6 1 0 0 1 1 1 0 P53 transactivation motif Sin_N PF04801.8 CAR28344.1 - 1.4e-16 60.4 0.1 2.5e-16 59.5 0.0 1.4 1 1 0 1 1 1 1 Sin-like protein conserved region IF-2B PF01008.12 CAR28345.1 - 1.5e-69 234.1 0.0 1.7e-69 233.9 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family GTP_EFTU PF00009.22 CAR28346.1 - 7.2e-58 195.1 0.0 2.5e-57 193.3 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 CAR28346.1 - 1.3e-24 85.8 0.0 3.2e-24 84.5 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 CAR28346.1 - 9.1e-19 67.1 0.2 1.8e-17 62.9 0.1 2.4 1 1 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CAR28346.1 - 3.1e-06 27.1 0.0 1e-05 25.5 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CAR28346.1 - 0.00082 19.3 0.1 0.0021 18.0 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gp_dh_C PF02800.15 CAR28346.1 - 0.078 12.4 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain GCS PF03074.11 CAR28347.1 - 2.2e-139 464.6 0.0 2.8e-139 464.2 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase PI3_PI4_kinase PF00454.22 CAR28348.1 - 1.5e-55 188.2 0.1 1.9e-55 187.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase ChAPs PF09295.5 CAR28349.1 - 2.2e-50 171.5 0.9 4.6e-41 140.9 0.2 2.1 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 CAR28349.1 - 1.6e-05 24.4 0.1 0.00018 21.0 0.1 2.2 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 CAR28349.1 - 2.8e-05 23.6 1.5 0.0056 16.5 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 CAR28349.1 - 6.6e-05 22.3 0.2 0.00025 20.5 0.2 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 CAR28349.1 - 0.00013 22.1 1.1 0.0014 18.8 0.2 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 CAR28349.1 - 0.00024 20.6 0.6 0.004 16.8 0.2 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CAR28349.1 - 0.00066 19.7 0.1 0.002 18.2 0.1 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 CAR28349.1 - 0.0011 18.8 0.7 0.016 15.1 0.4 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 CAR28349.1 - 0.0045 16.8 0.1 0.075 12.8 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 CAR28349.1 - 0.0049 17.5 0.0 0.013 16.1 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 CAR28349.1 - 0.019 15.1 0.4 0.46 10.7 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat YtzH PF14165.1 CAR28350.1 - 0.18 12.0 0.7 0.29 11.4 0.5 1.4 1 0 0 1 1 1 0 YtzH-like protein Dak2 PF02734.12 CAR28351.1 - 0.014 15.1 0.0 0.019 14.6 0.0 1.4 1 1 0 1 1 1 0 DAK2 domain Metallothio_PEC PF02068.11 CAR28352.1 - 0.068 13.5 0.1 0.075 13.4 0.1 1.1 1 0 0 1 1 1 0 Plant PEC family metallothionein Sod_Cu PF00080.15 CAR28353.1 - 3.7e-22 79.0 0.0 4.5e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) MFS_1 PF07690.11 CAR28354.1 - 1.5e-34 119.3 23.6 1.5e-34 119.3 16.4 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1129 PF06570.6 CAR28354.1 - 0.1 11.8 0.5 0.25 10.6 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Ndc1_Nup PF09531.5 CAR28354.1 - 0.1 10.9 1.3 0.19 10.1 0.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MFS_1 PF07690.11 CAR28358.1 - 2.6e-31 108.6 24.7 1.7e-30 105.9 15.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Zip PF02535.17 CAR28359.1 - 1e-54 185.7 4.5 1.2e-54 185.5 3.1 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter ADH_zinc_N PF00107.21 CAR28360.1 - 7.3e-16 57.8 0.1 1.2e-15 57.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CRC_subunit PF08624.5 CAR28361.1 - 4.7e-31 107.5 0.2 1.7e-30 105.7 0.0 1.9 2 0 0 2 2 2 1 Chromatin remodelling complex Rsc7/Swp82 subunit Lectin_leg-like PF03388.8 CAR28362.1 - 1.5e-42 145.3 0.5 2.2e-42 144.7 0.3 1.2 1 0 0 1 1 1 1 Legume-like lectin family DivIVA PF05103.8 CAR28362.1 - 0.011 15.8 1.2 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 DivIVA protein Rdx PF10262.4 CAR28363.1 - 1.6e-25 88.8 0.1 2.1e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Rdx family FCH PF00611.18 CAR28364.1 - 3e-17 62.5 0.2 3e-16 59.3 0.0 2.7 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain RhoGAP PF00620.22 CAR28364.1 - 8.4e-13 48.1 5.9 7.8e-12 45.0 0.4 2.6 2 0 0 2 2 2 2 RhoGAP domain DEP PF00610.16 CAR28364.1 - 2.9e-11 42.9 0.1 7.9e-11 41.5 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) V-SNARE_C PF12352.3 CAR28366.1 - 6.3e-07 29.3 3.1 9.2e-07 28.8 2.2 1.3 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 CAR28366.1 - 1.2e-05 24.8 0.8 2.1e-05 24.1 0.5 1.3 1 0 0 1 1 1 1 Sec20 DNA_pol_lambd_f PF10391.4 CAR28366.1 - 0.13 11.8 0.2 0.24 10.9 0.1 1.4 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda Use1 PF09753.4 CAR28366.1 - 0.16 11.4 2.9 0.3 10.5 2.0 1.6 1 1 0 1 1 1 0 Membrane fusion protein Use1 RCC1 PF00415.13 CAR28367.1 - 8.2e-27 93.1 2.1 8.3e-09 35.5 0.0 5.0 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CAR28367.1 - 8e-10 38.0 11.7 8.9e-08 31.5 0.0 4.6 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat YcxB PF14317.1 CAR28367.1 - 0.13 11.5 1.2 1.5 8.1 0.1 3.0 3 0 0 3 3 3 0 YcxB-like protein DUF1640 PF07798.6 CAR28368.1 - 4.1e-61 206.0 9.6 4.9e-61 205.8 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) FTA4 PF13093.1 CAR28368.1 - 0.015 14.7 8.7 0.021 14.2 6.0 1.4 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 HALZ PF02183.13 CAR28368.1 - 0.027 14.1 1.4 0.11 12.1 0.8 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF3584 PF12128.3 CAR28368.1 - 0.052 10.8 11.6 0.16 9.2 6.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF3410 PF11890.3 CAR28368.1 - 0.092 12.3 5.1 0.033 13.8 1.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3410) TBPIP PF07106.8 CAR28368.1 - 0.1 12.1 10.1 0.12 11.9 6.4 1.6 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FlaC_arch PF05377.6 CAR28368.1 - 0.17 11.7 2.4 8.4 6.3 0.1 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Spore_GerAC PF05504.6 CAR28368.1 - 0.31 10.8 4.7 0.7 9.6 2.9 1.9 1 1 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Baculo_PEP_C PF04513.7 CAR28368.1 - 0.34 10.7 3.6 2.2 8.1 2.5 2.2 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus PLRV_ORF5 PF01690.12 CAR28368.1 - 0.54 9.3 3.1 0.68 9.0 0.1 1.9 1 1 1 2 2 2 0 Potato leaf roll virus readthrough protein ThiF PF00899.16 CAR28368.1 - 0.79 9.5 2.8 2.7 7.8 0.0 2.2 1 1 1 2 2 2 0 ThiF family V-ATPase_G PF03179.10 CAR28368.1 - 1 9.6 6.4 0.5 10.6 2.5 2.0 2 1 1 3 3 2 0 Vacuolar (H+)-ATPase G subunit TPR_MLP1_2 PF07926.7 CAR28368.1 - 1.2 8.8 10.7 4.8 6.9 7.0 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Syntaxin PF00804.20 CAR28368.1 - 1.6 8.9 14.8 8.5 6.6 6.2 2.4 1 1 1 2 2 2 0 Syntaxin DUF1777 PF08648.7 CAR28368.1 - 1.7 8.3 6.4 1.6 8.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) Phage_lysis PF03245.8 CAR28368.1 - 3.1 7.7 7.4 0.74 9.8 0.6 2.4 1 1 1 2 2 2 0 Bacteriophage Rz lysis protein YlqD PF11068.3 CAR28368.1 - 3.3 7.7 12.1 1.4 8.9 3.4 2.4 1 1 1 2 2 2 0 YlqD protein DUF342 PF03961.8 CAR28368.1 - 3.5 5.9 7.3 4.5 5.5 5.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Fib_alpha PF08702.5 CAR28368.1 - 4.4 7.4 11.2 0.6 10.2 2.7 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Atg14 PF10186.4 CAR28368.1 - 5.7 5.7 12.1 22 3.8 8.4 1.9 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1451 PF07295.6 CAR28368.1 - 7.8 6.2 7.8 4.7 6.9 3.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1451) PMM PF03332.8 CAR28369.1 - 2.4e-113 377.1 0.7 2.7e-113 376.9 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 CAR28369.1 - 1.2e-05 25.0 0.0 0.00024 20.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 CAR28369.1 - 0.015 14.6 0.0 0.56 9.4 0.0 2.0 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Trehalose_PPase PF02358.11 CAR28369.1 - 0.11 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Trehalose-phosphatase Ribosomal_L16 PF00252.13 CAR28370.1 - 1e-32 112.7 0.1 1.3e-32 112.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e zf-C2H2_jaz PF12171.3 CAR28371.1 - 4.8e-09 36.1 4.2 4.8e-09 36.1 2.9 1.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CAR28371.1 - 0.00037 20.5 1.5 0.00054 20.0 0.5 1.6 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-AD PF07776.10 CAR28371.1 - 0.002 18.0 0.1 0.0044 16.9 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger associated domain (zf-AD) zf-met PF12874.2 CAR28371.1 - 0.062 13.5 3.6 0.11 12.6 2.5 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type OTU PF02338.14 CAR28372.1 - 1.9e-11 44.6 0.0 3.2e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 CAR28372.1 - 0.043 13.1 0.0 0.12 11.7 0.0 1.7 1 1 1 2 2 2 0 Peptidase C65 Otubain GRAM PF02893.15 CAR28373.1 - 1.3e-20 72.6 0.3 6.1e-20 70.5 0.1 2.2 2 0 0 2 2 2 1 GRAM domain CENP-X PF09415.5 CAR28373.1 - 0.047 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Med14 PF08638.6 CAR28374.1 - 1.6e-56 190.6 0.9 1.6e-56 190.6 0.6 2.5 3 0 0 3 3 3 1 Mediator complex subunit MED14 ADH_N PF08240.7 CAR28375.1 - 5.2e-29 100.1 0.3 1.1e-28 99.1 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CAR28375.1 - 8.6e-27 93.2 0.2 1.4e-26 92.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CAR28375.1 - 7.2e-06 26.9 0.0 1.2e-05 26.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 CAR28375.1 - 0.0046 16.5 0.3 0.0084 15.6 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 CAR28375.1 - 0.012 15.0 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 CAR28375.1 - 0.15 11.1 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cu-oxidase_2 PF07731.9 CAR28376.1 - 4.4e-41 139.6 9.9 1.1e-37 128.6 1.1 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 CAR28376.1 - 4e-38 129.7 6.9 5.9e-35 119.5 0.7 3.7 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 CAR28376.1 - 9e-35 119.9 4.6 1.5e-31 109.4 0.1 3.5 3 1 0 3 3 3 2 Multicopper oxidase Fibritin_C PF07921.7 CAR28376.1 - 0.099 12.5 0.0 0.92 9.4 0.0 2.2 2 0 0 2 2 2 0 Fibritin C-terminal region GTP_EFTU PF00009.22 CAR28377.1 - 8.8e-60 201.3 0.1 1.6e-59 200.4 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CAR28377.1 - 9.1e-34 115.6 0.0 2.1e-33 114.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 CAR28377.1 - 8.8e-30 102.3 0.0 1.8e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 CAR28377.1 - 1.4e-24 85.7 0.0 3e-24 84.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CAR28377.1 - 1.4e-12 47.5 0.1 4.8e-12 45.8 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Miro PF08477.8 CAR28377.1 - 0.0099 16.3 0.0 0.024 15.1 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein rRNA_processing PF08524.6 CAR28378.1 - 6.4e-44 149.3 34.8 6.9e-44 149.2 24.1 1.0 1 0 0 1 1 1 1 rRNA processing IpaC_SipC PF09599.5 CAR28378.1 - 0.018 14.0 11.9 0.023 13.7 8.2 1.1 1 0 0 1 1 1 0 Salmonella-Shigella invasin protein C (IpaC_SipC) DinB PF05163.7 CAR28378.1 - 0.02 14.6 1.7 0.023 14.3 1.2 1.1 1 0 0 1 1 1 0 DinB family APG6 PF04111.7 CAR28378.1 - 9.2 5.2 17.5 10 5.0 12.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 SH3_1 PF00018.23 CAR28379.1 - 6.8e-09 34.9 0.2 1.9e-08 33.5 0.2 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CAR28379.1 - 3.3e-07 29.7 0.3 9.6e-07 28.3 0.2 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CAR28379.1 - 3.9e-05 23.0 0.0 9.7e-05 21.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PPR_3 PF13812.1 CAR28380.1 - 5.6e-11 41.8 4.4 0.0058 16.8 0.0 8.8 10 0 0 10 10 10 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 CAR28380.1 - 6.8e-10 38.7 8.7 0.00011 22.0 0.1 7.1 3 2 5 8 8 8 5 PPR repeat family PPR PF01535.15 CAR28380.1 - 3.6e-09 35.9 8.9 0.00047 19.9 0.0 7.0 8 0 0 8 8 8 2 PPR repeat TPR_14 PF13428.1 CAR28380.1 - 0.0039 17.6 2.1 9.8 7.1 0.0 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat PPR_1 PF12854.2 CAR28380.1 - 0.0073 15.7 0.0 0.058 12.8 0.0 2.6 2 0 0 2 2 2 1 PPR repeat SPC22 PF04573.7 CAR28381.1 - 4e-51 172.7 0.4 4.5e-51 172.5 0.3 1.0 1 0 0 1 1 1 1 Signal peptidase subunit DUF939 PF06081.6 CAR28381.1 - 0.047 13.5 0.0 0.069 13.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF939) Sugar_tr PF00083.19 CAR28382.1 - 2.3e-53 181.3 19.6 3e-53 181.0 13.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR28382.1 - 9.8e-18 63.9 13.5 9.8e-18 63.9 9.3 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF2644 PF10841.3 CAR28382.1 - 0.33 11.0 7.9 3.4 7.7 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2644) Flo11 PF10182.4 CAR28383.1 - 8.8e-41 138.9 4.0 1.2e-19 70.3 0.2 2.3 2 0 0 2 2 2 2 Flo11 domain DUF3665 PF12427.3 CAR28383.1 - 0.13 11.6 5.6 3.6 7.0 0.3 3.0 2 0 0 2 2 2 0 Branched-chain amino acid aminotransferase Flo11 PF10182.4 CAR28384.1 - 1.7e-16 60.1 0.0 3.4e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Flo11 domain DUF3665 PF12427.3 CAR28384.1 - 1.8 7.9 20.8 0.87 9.0 0.5 5.0 4 0 0 4 4 4 0 Branched-chain amino acid aminotransferase Actin PF00022.14 CAR28385.1 - 1.3e-159 530.8 0.0 1.5e-159 530.6 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 CAR28385.1 - 0.043 14.2 0.0 0.18 12.1 0.0 2.0 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF788 PF05620.6 CAR28386.1 - 3.2e-49 167.0 0.1 3.6e-49 166.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) VirB3 PF05101.8 CAR28386.1 - 0.79 9.7 3.2 24 4.9 0.3 2.4 2 1 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein Ras PF00071.17 CAR28387.1 - 1.5e-64 216.2 0.6 1.8e-64 216.0 0.4 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR28387.1 - 2.4e-19 69.9 0.1 3.6e-19 69.4 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAR28387.1 - 5e-17 61.6 0.2 6.3e-17 61.3 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CAR28387.1 - 1.7e-06 27.3 0.3 2.3e-06 26.9 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CAR28387.1 - 7.5e-06 25.5 0.2 1.5e-05 24.5 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CAR28387.1 - 7.3e-05 22.7 0.1 0.0001 22.2 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CAR28387.1 - 0.0017 17.6 0.1 0.0025 17.0 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 CAR28387.1 - 0.013 15.6 0.0 0.025 14.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 CAR28387.1 - 0.019 14.1 0.0 0.038 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 PduV-EutP PF10662.4 CAR28387.1 - 0.022 14.2 0.1 0.084 12.3 0.1 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation YTH PF04146.10 CAR28387.1 - 0.037 13.6 0.1 0.048 13.2 0.1 1.2 1 0 0 1 1 1 0 YT521-B-like domain FeoB_N PF02421.13 CAR28387.1 - 0.04 13.2 0.2 0.24 10.6 0.2 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.1 CAR28387.1 - 0.046 13.7 0.2 0.22 11.5 0.1 1.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.9 CAR28387.1 - 0.05 13.3 0.0 0.075 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 CAR28387.1 - 0.052 13.0 0.0 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 CAR28387.1 - 0.15 12.3 0.8 0.35 11.1 0.5 2.0 1 1 0 1 1 1 0 ABC transporter UPF0121 PF03661.8 CAR28388.1 - 0.00046 19.4 15.7 0.00064 18.9 10.9 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) O-antigen_lig PF13425.1 CAR28388.1 - 0.064 13.2 0.3 0.064 13.2 0.2 2.3 2 1 0 2 2 2 0 O-antigen ligase like membrane protein Tubulin PF00091.20 CAR28389.1 - 1.5e-69 234.1 0.0 2.4e-69 233.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CAR28389.1 - 1.1e-48 164.4 0.0 2.7e-48 163.1 0.0 1.7 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CAR28389.1 - 0.0086 16.1 0.0 0.021 14.8 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CAR28389.1 - 0.025 14.0 0.0 0.044 13.2 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain MVL PF12151.3 CAR28389.1 - 0.031 13.9 0.0 0.096 12.3 0.0 1.9 1 0 0 1 1 1 0 Mannan-binding protein RNA_pol PF00940.14 CAR28390.1 - 8.2e-165 548.1 0.3 1.8e-164 547.0 0.1 1.7 2 0 0 2 2 2 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 CAR28390.1 - 1e-90 304.2 1.7 1.9e-90 303.3 1.2 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Mob1_phocein PF03637.12 CAR28391.1 - 5.2e-71 237.9 2.2 6.5e-71 237.5 1.5 1.1 1 0 0 1 1 1 1 Mob1/phocein family DUF3115 PF11312.3 CAR28392.1 - 2e-98 329.1 0.0 2.2e-98 328.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) Ribosomal_L22e PF01776.12 CAR28393.1 - 5e-43 145.6 0.5 5.8e-43 145.4 0.4 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF726 PF05277.7 CAR28394.1 - 4e-133 443.5 0.8 5.6e-133 443.1 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF1456 PF07308.8 CAR28394.1 - 0.047 13.7 0.1 0.14 12.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1456) B3_4 PF03483.12 CAR28395.1 - 9.8e-25 87.0 0.0 1.7e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 CAR28395.1 - 3.1e-21 74.9 0.0 7.3e-17 60.9 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain Pkinase PF00069.20 CAR28396.1 - 1.1e-60 205.0 0.0 6.6e-37 127.0 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAR28396.1 - 1.6e-25 89.6 0.1 3.9e-20 72.0 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CAR28396.1 - 7e-06 25.2 0.4 0.0007 18.6 0.0 2.6 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.9 CAR28396.1 - 0.00012 21.1 0.0 0.00024 20.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Response_reg PF00072.19 CAR28396.1 - 0.0013 18.6 0.0 0.0027 17.6 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain APH PF01636.18 CAR28396.1 - 0.0032 17.2 0.0 1 9.0 0.1 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Glyco_hydro_30 PF02055.11 CAR28396.1 - 0.052 11.7 0.1 0.24 9.5 0.0 1.8 2 0 0 2 2 2 0 O-Glycosyl hydrolase family 30 RNase_T PF00929.19 CAR28397.1 - 1.6e-29 103.2 0.0 2e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DUF4148 PF13663.1 CAR28397.1 - 0.042 13.7 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) 2OG-FeII_Oxy PF03171.15 CAR28398.1 - 7.8e-15 54.9 0.0 1.5e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 CAR28398.1 - 9.1e-15 55.2 0.0 1.4e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal bZIP_1 PF00170.16 CAR28399.1 - 2.9e-05 23.9 6.7 5.7e-05 22.9 4.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CAR28399.1 - 8.2e-05 22.3 8.7 8.2e-05 22.3 6.0 1.8 1 1 1 2 2 2 1 Basic region leucine zipper DUF2360 PF10152.4 CAR28399.1 - 0.018 15.3 0.6 0.03 14.6 0.2 1.4 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF566 PF04484.7 CAR28399.1 - 2.5 7.5 7.4 0.9 8.9 1.8 2.2 2 1 0 2 2 2 0 Family of unknown function (DUF566) Aminotran_5 PF00266.14 CAR28400.1 - 8.6e-26 90.5 0.0 1.1e-25 90.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 CAR28400.1 - 0.0016 18.3 0.1 0.013 15.3 0.0 2.1 2 0 0 2 2 2 1 B12 binding domain Aminotran_1_2 PF00155.16 CAR28400.1 - 0.041 12.8 0.0 0.06 12.2 0.0 1.4 1 1 0 1 1 1 0 Aminotransferase class I and II SHMT PF00464.14 CAR28401.1 - 1.2e-205 682.5 0.0 1.3e-205 682.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 CAR28401.1 - 4.4e-06 25.8 0.0 8.2e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 CAR28401.1 - 7.2e-05 21.6 0.0 0.0001 21.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CAR28401.1 - 0.00034 19.8 0.0 0.00086 18.5 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase FR47 PF08445.5 CAR28401.1 - 0.052 13.3 0.0 0.25 11.1 0.0 2.0 2 0 0 2 2 2 0 FR47-like protein Glyco_hydro_47 PF01532.15 CAR28402.1 - 4.4e-87 292.6 0.3 5.8e-87 292.2 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.9 CAR28402.1 - 0.17 11.2 0.3 2.8 7.2 0.0 2.4 3 0 0 3 3 3 0 Glycosyl hydrolase family 76 Pkinase PF00069.20 CAR28403.1 - 4.6e-28 98.0 0.0 4.6e-27 94.7 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR28403.1 - 3.4e-15 55.8 0.0 4.9e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CAR28403.1 - 0.0044 16.7 0.0 0.042 13.5 0.1 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CAR28403.1 - 0.074 12.3 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 CAR28403.1 - 0.11 11.5 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 CAR28403.1 - 0.13 11.0 0.2 1.5 7.5 0.0 2.3 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase FA_hydroxylase PF04116.8 CAR28404.1 - 4.3e-11 43.2 16.5 4.3e-11 43.2 11.5 2.3 1 1 2 3 3 3 1 Fatty acid hydroxylase superfamily malic PF00390.14 CAR28404.1 - 0.005 16.4 0.0 0.0097 15.5 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain ABC_tran PF00005.22 CAR28405.1 - 3.3e-17 63.0 0.0 1.6e-16 60.8 0.0 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CAR28405.1 - 9.8e-14 51.9 0.0 5.8e-07 29.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 CAR28405.1 - 3.1e-06 26.4 0.0 0.014 14.4 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 CAR28405.1 - 1.3e-05 24.5 0.1 0.073 12.2 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CAR28405.1 - 0.00033 20.1 0.0 0.00063 19.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 CAR28405.1 - 0.0026 17.2 0.4 0.019 14.4 0.1 2.0 1 1 0 2 2 2 1 AAA-like domain AAA_24 PF13479.1 CAR28405.1 - 0.0045 16.5 0.0 0.0079 15.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.1 CAR28405.1 - 0.0078 16.5 0.0 0.011 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CAR28405.1 - 0.011 16.5 1.2 0.033 14.9 0.9 2.1 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 CAR28405.1 - 0.012 14.7 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 CAR28405.1 - 0.028 13.8 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Viral_helicase1 PF01443.13 CAR28405.1 - 0.028 13.9 0.2 2.3 7.6 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Dynamin_N PF00350.18 CAR28405.1 - 0.031 14.1 0.4 0.046 13.5 0.3 1.3 1 0 0 1 1 1 0 Dynamin family ArgK PF03308.11 CAR28405.1 - 0.053 12.2 0.0 0.087 11.5 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_18 PF13238.1 CAR28405.1 - 0.056 13.7 1.1 0.19 12.0 0.6 2.0 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CAR28405.1 - 0.06 12.7 0.1 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 CAR28405.1 - 0.11 11.9 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.7 CAR28405.1 - 0.14 11.1 0.1 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 CAR28405.1 - 0.15 11.9 0.1 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 CAR28406.1 - 5e-12 45.2 3.5 0.025 14.4 0.0 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat RabGAP-TBC PF00566.13 CAR28407.1 - 5.6e-21 74.9 8.5 7e-20 71.4 5.9 2.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF3753 PF12575.3 CAR28407.1 - 2.8 7.7 6.9 17 5.2 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3753) STE2 PF02116.10 CAR28408.1 - 2.7e-95 318.6 23.7 3.2e-95 318.4 16.4 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR PGAP1 PF07819.8 CAR28409.1 - 2.8e-87 292.0 0.0 4.4e-87 291.3 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 CAR28409.1 - 0.0026 17.5 0.0 0.0066 16.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CAR28409.1 - 0.003 17.4 0.0 0.0052 16.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAR28409.1 - 0.0053 16.3 0.0 0.0086 15.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 CAR28409.1 - 0.07 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.20 CAR28409.1 - 0.08 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) EPL1 PF10513.4 CAR28410.1 - 7.8e-34 117.2 5.6 7.8e-34 117.2 3.9 4.0 3 2 0 3 3 3 1 Enhancer of polycomb-like DUF3835 PF12927.2 CAR28411.1 - 6.3e-16 59.0 0.3 6.3e-16 59.0 0.2 8.6 9 3 1 11 11 11 2 Domain of unknown function (DUF3835) Prefoldin PF02996.12 CAR28411.1 - 1e-05 25.1 0.4 1e-05 25.1 0.3 3.4 5 0 0 5 5 5 1 Prefoldin subunit GCR1_C PF12550.3 CAR28412.1 - 1.4e-12 47.2 2.9 1.1e-09 38.0 0.2 2.8 3 0 0 3 3 3 2 Transcriptional activator of glycolytic enzymes tRNA-synt_2d PF01409.15 CAR28415.1 - 1e-87 293.4 0.0 1.2e-87 293.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 CAR28415.1 - 6.5e-07 28.4 0.2 7.4e-06 24.9 0.0 2.4 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 CAR28415.1 - 1e-06 28.4 0.0 2.2e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_His PF13393.1 CAR28415.1 - 0.0045 16.0 0.0 0.01 14.9 0.0 1.5 1 0 0 1 1 1 1 Histidyl-tRNA synthetase Pneumo_att_G PF05539.6 CAR28416.1 - 0.071 12.4 1.2 0.11 11.8 0.8 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Fcf2 PF08698.6 CAR28417.1 - 1.4e-27 95.6 0.6 2.4e-27 94.8 0.4 1.4 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing GATA PF00320.22 CAR28418.1 - 6.6e-17 60.5 2.5 1.3e-16 59.6 1.7 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 CAR28418.1 - 4e-11 42.2 1.5 7e-11 41.5 1.0 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Pyr_redox_dim PF02852.17 CAR28419.1 - 2.8e-42 143.1 0.2 8.1e-42 141.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 CAR28419.1 - 6.1e-38 130.7 11.0 2.5e-36 125.4 7.6 3.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CAR28419.1 - 1.3e-21 76.7 8.7 9.4e-19 67.6 0.5 3.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CAR28419.1 - 2.2e-14 53.4 4.0 1.1e-11 44.4 0.1 2.8 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CAR28419.1 - 5.2e-10 39.7 0.3 5e-07 29.9 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CAR28419.1 - 1.6e-08 34.4 5.3 0.00068 19.6 1.3 2.9 2 1 1 3 3 3 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 CAR28419.1 - 4.7e-08 32.2 7.4 5.4e-07 28.8 4.6 2.5 1 1 1 2 2 2 1 Glucose inhibited division protein A DAO PF01266.19 CAR28419.1 - 1.1e-07 31.1 7.9 0.0019 17.1 0.1 3.7 3 1 1 4 4 4 3 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CAR28419.1 - 2e-07 30.2 11.4 5e-07 28.9 2.0 2.8 2 1 1 3 3 3 2 FAD binding domain FAD_binding_3 PF01494.14 CAR28419.1 - 1.3e-05 24.4 9.1 0.012 14.6 0.7 3.6 2 1 0 2 2 2 2 FAD binding domain HI0933_like PF03486.9 CAR28419.1 - 2.6e-05 22.8 10.1 0.0006 18.3 0.7 4.0 3 1 1 4 4 4 1 HI0933-like protein Thi4 PF01946.12 CAR28419.1 - 9.7e-05 21.5 3.0 0.001 18.2 0.6 2.5 2 1 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.16 CAR28419.1 - 0.00043 19.8 0.7 0.023 14.2 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.1 CAR28419.1 - 0.00087 18.3 0.5 2.1 7.1 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.13 CAR28419.1 - 0.012 15.2 1.7 0.067 12.8 0.1 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 CAR28419.1 - 0.17 12.1 0.9 8.4 6.7 0.1 2.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Trp_halogenase PF04820.9 CAR28419.1 - 0.54 8.8 2.4 0.8 8.2 0.4 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.7 CAR28419.1 - 0.76 8.6 2.6 1.6 7.5 0.5 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein LSM PF01423.17 CAR28420.1 - 6.6e-15 54.4 0.1 7.5e-15 54.2 0.1 1.0 1 0 0 1 1 1 1 LSM domain Acetyltransf_1 PF00583.19 CAR28421.1 - 5.7e-15 55.1 0.0 8.1e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CAR28421.1 - 1.2e-10 41.3 0.1 1.7e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CAR28421.1 - 5.2e-06 26.5 0.0 6e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CAR28421.1 - 1.4e-05 24.9 0.0 2.4e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CAR28421.1 - 0.0026 17.7 0.0 0.003 17.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CAR28421.1 - 0.015 15.1 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF2781 PF10914.3 CAR28423.1 - 1.8e-29 102.4 5.7 2e-29 102.2 3.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) DUF411 PF04214.8 CAR28423.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF DnaJ PF00226.26 CAR28424.1 - 5.6e-23 80.4 2.5 1.1e-22 79.5 1.7 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CAR28424.1 - 1.1e-20 73.3 0.4 5.1e-15 55.1 0.1 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CAR28424.1 - 1.2e-11 44.4 20.5 2e-11 43.7 14.2 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 CAR28424.1 - 0.00026 20.6 7.8 0.0019 17.8 1.1 2.3 1 1 1 2 2 2 2 Hydrogenase expression/synthesis hypA family Cytochrom_c3_2 PF14537.1 CAR28424.1 - 0.01 16.1 9.4 0.027 14.7 6.5 1.7 1 0 0 1 1 1 0 Cytochrome c3 Cytochrome_C7 PF14522.1 CAR28424.1 - 0.7 9.5 14.0 3.1 7.4 9.8 2.1 1 1 0 1 1 1 0 Cytochrome c7 PADR1 PF08063.7 CAR28424.1 - 3.2 7.2 12.8 20 4.6 1.8 3.2 1 1 2 3 3 3 0 PADR1 (NUC008) domain DZR PF12773.2 CAR28424.1 - 9.3 6.1 13.9 37 4.2 6.7 2.3 1 1 0 1 1 1 0 Double zinc ribbon DUF336 PF03928.9 CAR28425.1 - 0.0033 17.2 0.0 0.0097 15.7 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF336) OTU PF02338.14 CAR28425.1 - 0.041 14.4 0.0 0.062 13.8 0.0 1.4 1 0 0 1 1 1 0 OTU-like cysteine protease Meleagrin PF08189.6 CAR28425.1 - 1.1 8.8 3.3 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 Meleagrin/Cygnin family HSP9_HSP12 PF04119.7 CAR28426.1 - 8.1e-23 80.2 6.2 7.7e-22 77.1 3.0 2.1 2 0 0 2 2 2 1 Heat shock protein 9/12 DUF1771 PF08590.5 CAR28426.1 - 0.015 15.3 1.2 0.073 13.0 0.1 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1771) Apolipoprotein PF01442.13 CAR28426.1 - 0.047 13.2 1.6 0.092 12.2 1.1 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain YtxH PF12732.2 CAR28426.1 - 0.053 13.8 6.4 6 7.3 4.4 2.3 1 1 0 1 1 1 0 YtxH-like protein Autophagy_N PF03986.8 CAR28426.1 - 0.059 13.1 1.2 0.077 12.7 0.8 1.1 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain DUF357 PF04010.8 CAR28426.1 - 0.068 12.8 0.2 5.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF357) DUF2357 PF09823.4 CAR28426.1 - 0.087 11.9 0.3 0.093 11.8 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) DUF883 PF05957.8 CAR28426.1 - 0.13 12.6 1.8 3.9 7.9 0.2 2.1 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF2413 PF10310.4 CAR28426.1 - 0.16 10.7 7.7 0.18 10.5 5.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) MT0933_antitox PF14013.1 CAR28426.1 - 0.45 10.6 7.2 5.4 7.2 2.5 2.8 1 1 1 2 2 2 0 MT0933-like antitoxin protein DUF1044 PF06296.7 CAR28426.1 - 0.99 9.2 3.2 2.7 7.8 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1044) KLRAQ PF10205.4 CAR28427.1 - 0.074 13.0 0.8 0.16 12.0 0.5 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein WW PF00397.21 CAR28429.1 - 1.1e-06 28.3 1.9 1.9e-06 27.6 1.3 1.4 1 0 0 1 1 1 1 WW domain WD40 PF00400.27 CAR28430.1 - 2.4e-44 147.6 21.5 3.9e-10 39.2 1.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 CAR28430.1 - 3.3e-11 42.7 0.7 6.9e-11 41.7 0.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CAR28430.1 - 4.8e-09 35.6 0.2 1.1e-08 34.4 0.1 1.6 1 0 0 1 1 1 1 F-box domain JmjC PF02373.17 CAR28430.1 - 0.0097 16.1 0.0 0.032 14.4 0.0 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase PRANC PF09372.5 CAR28430.1 - 0.044 13.7 4.5 0.035 14.0 0.7 2.6 2 1 0 2 2 2 0 PRANC domain Herpes_gE PF02480.11 CAR28431.1 - 0.0027 16.0 0.0 1 7.5 0.0 2.0 1 1 1 2 2 2 2 Alphaherpesvirus glycoprotein E NicO PF03824.11 CAR28431.1 - 0.019 14.3 0.2 0.026 13.8 0.1 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein INSIG PF07281.7 CAR28431.1 - 0.022 14.1 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Insulin-induced protein (INSIG) SMC_N PF02463.14 CAR28432.1 - 8.8e-53 178.7 43.9 3.7e-52 176.7 30.4 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CAR28432.1 - 1.6e-25 89.3 0.0 4.3e-25 88.0 0.0 1.8 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 CAR28432.1 - 1.2e-08 35.5 37.3 1.2e-08 35.5 25.9 6.7 3 2 1 4 4 4 1 AAA domain AAA_21 PF13304.1 CAR28432.1 - 2.5e-08 34.2 14.9 5e-06 26.6 2.1 4.4 3 1 0 4 4 4 2 AAA domain AAA_29 PF13555.1 CAR28432.1 - 1.1e-07 31.2 0.0 2.4e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 CAR28432.1 - 0.42 11.4 0.0 0.42 11.4 0.0 5.4 3 2 1 4 4 4 0 AAA domain Reo_sigmaC PF04582.7 CAR28432.1 - 2.4 7.2 30.0 0.062 12.4 0.4 5.1 3 2 0 4 4 4 0 Reovirus sigma C capsid protein DUF3437 PF11919.3 CAR28433.1 - 9.6e-30 102.1 0.2 1.1e-28 98.7 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) UTP15_C PF09384.5 CAR28433.1 - 0.0049 16.5 0.2 0.023 14.3 0.0 2.3 2 0 0 2 2 2 1 UTP15 C terminal Ras PF00071.17 CAR28434.1 - 7.2e-64 214.0 0.3 8.8e-64 213.7 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR28434.1 - 2.4e-19 69.9 0.1 3.8e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAR28434.1 - 8.5e-19 67.4 0.1 1e-18 67.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CAR28434.1 - 2e-07 30.3 0.1 2.4e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CAR28434.1 - 3.2e-07 29.7 0.2 4e-07 29.4 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 CAR28434.1 - 3.5e-06 26.5 0.2 4e-05 23.1 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CAR28434.1 - 1.5e-05 24.9 0.1 2.3e-05 24.2 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CAR28434.1 - 0.00015 20.9 0.1 0.039 13.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 FeoB_N PF02421.13 CAR28434.1 - 0.0018 17.5 0.1 0.034 13.4 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.1 CAR28434.1 - 0.0042 17.2 0.1 0.02 15.0 0.0 2.3 1 1 2 3 3 3 1 AAA domain AAA_16 PF13191.1 CAR28434.1 - 0.0055 16.7 0.3 0.018 15.0 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 CAR28434.1 - 0.009 15.5 4.6 0.14 11.7 0.8 3.2 3 1 1 4 4 4 1 P-loop containing region of AAA domain MCM PF00493.18 CAR28434.1 - 0.032 13.0 0.0 0.062 12.0 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family AAA PF00004.24 CAR28434.1 - 0.04 14.1 0.0 0.74 10.0 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.15 CAR28434.1 - 0.073 11.7 0.9 1.2 7.7 0.0 2.5 1 1 1 2 2 2 0 G-protein alpha subunit PduV-EutP PF10662.4 CAR28434.1 - 0.098 12.1 0.0 0.27 10.6 0.0 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 CAR28434.1 - 3.8 7.7 5.0 0.89 9.8 0.1 2.4 1 1 0 2 2 2 0 ABC transporter VTC PF09359.5 CAR28435.1 - 6e-94 314.2 0.1 1.2e-93 313.2 0.0 1.5 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 CAR28435.1 - 1.3e-21 77.6 21.2 1.6e-14 54.3 1.0 3.7 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 CAR28435.1 - 2.6e-10 40.3 2.2 2.6e-10 40.3 1.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4149 PF13664.1 CAR28435.1 - 0.0045 17.0 2.0 0.008 16.2 1.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4149) DUF4234 PF14018.1 CAR28435.1 - 0.074 12.7 2.9 0.071 12.8 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) Peptidase_C48 PF02902.14 CAR28436.1 - 2.6e-38 131.8 7.5 5.6e-38 130.7 0.0 3.0 2 1 1 3 3 3 2 Ulp1 protease family, C-terminal catalytic domain MutS_V PF00488.16 CAR28437.1 - 1.4e-61 207.9 0.1 2.5e-61 207.1 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CAR28437.1 - 1.1e-29 103.7 1.3 2.7e-29 102.4 0.9 1.7 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 CAR28437.1 - 7.8e-12 45.2 1.3 6e-11 42.3 0.0 2.9 3 0 0 3 3 3 1 MutS family domain IV MutS_II PF05188.12 CAR28437.1 - 1.6e-09 37.9 1.0 3.3e-09 36.9 0.1 2.0 2 0 0 2 2 2 1 MutS domain II SIR2 PF02146.12 CAR28438.1 - 2.6e-50 170.6 0.0 3.6e-50 170.1 0.0 1.2 1 0 0 1 1 1 1 Sir2 family zf-LYAR PF08790.6 CAR28438.1 - 0.074 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger DUF3562 PF12085.3 CAR28438.1 - 0.2 11.5 0.8 0.33 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3562) DUF3696 PF12476.3 CAR28438.1 - 0.38 10.7 2.6 1.3 9.0 1.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3696) DUF3441 PF11923.3 CAR28439.1 - 1.8e-34 117.7 2.0 5.8e-34 116.0 0.7 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3441) FbpA PF05833.6 CAR28439.1 - 9.8e-24 83.7 0.3 9.8e-24 83.7 0.2 3.2 3 1 0 3 3 3 2 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 CAR28439.1 - 2.1e-09 37.1 0.0 5.9e-09 35.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Zip PF02535.17 CAR28439.1 - 3.6 6.4 10.9 0.25 10.2 2.9 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter Clat_adaptor_s PF01217.15 CAR28440.1 - 6.6e-17 61.5 0.5 2.9e-16 59.4 0.4 1.7 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Bromo_TP PF07524.8 CAR28441.1 - 7.2e-06 25.6 0.0 1.3e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated NUC173 PF08161.7 CAR28442.1 - 7.3e-73 244.1 0.0 2.2e-71 239.3 0.0 3.0 3 0 0 3 3 3 1 NUC173 domain TraE PF05309.6 CAR28442.1 - 0.0029 16.8 0.2 0.0058 15.8 0.1 1.4 1 0 0 1 1 1 1 TraE protein HEAT PF02985.17 CAR28442.1 - 0.0067 16.4 0.7 34 4.8 0.0 4.9 5 0 0 5 5 5 1 HEAT repeat Ribosomal_S16 PF00886.14 CAR28443.1 - 3e-24 84.4 0.1 3.9e-24 84.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 DEAD_2 PF06733.10 CAR28445.1 - 1.1e-49 168.2 0.0 1.8e-49 167.5 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 CAR28445.1 - 2e-46 158.0 0.0 3.5e-46 157.1 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD PF00270.24 CAR28445.1 - 2.7e-05 23.7 0.0 0.029 13.8 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 CAR28445.1 - 0.00029 20.7 0.0 0.65 9.7 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CAR28445.1 - 0.0017 18.0 0.0 0.0065 16.1 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 CAR28445.1 - 0.0024 18.0 0.1 1.4 9.0 0.1 2.9 2 1 0 2 2 2 2 AAA domain PhoH PF02562.11 CAR28445.1 - 0.05 12.8 0.0 4.4 6.4 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein Zot PF05707.7 CAR28445.1 - 0.079 12.4 0.0 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) zf-TFIIIC PF12660.2 CAR28446.1 - 3.6e-09 36.4 0.0 8.1e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex TFIIIC_delta PF12657.2 CAR28446.1 - 0.0062 16.2 1.2 4.8 6.8 0.1 3.4 3 1 0 3 3 3 2 Transcription factor IIIC subunit delta N-term WD40 PF00400.27 CAR28446.1 - 0.0073 16.1 0.0 6.1 6.8 0.0 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat Patched PF02460.13 CAR28447.1 - 8.1e-58 196.0 28.0 1.8e-29 102.3 3.0 3.2 1 1 0 2 2 2 2 Patched family Sterol-sensing PF12349.3 CAR28447.1 - 1.2e-39 135.1 8.1 1.2e-39 135.1 5.6 2.9 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 CAR28447.1 - 2.9e-05 22.9 23.3 0.00093 18.0 6.4 2.2 2 0 0 2 2 2 2 MMPL family ACR_tran PF00873.14 CAR28447.1 - 0.0023 15.4 20.3 0.0019 15.7 10.6 2.1 2 0 0 2 2 2 2 AcrB/AcrD/AcrF family PPR_2 PF13041.1 CAR28448.1 - 5.8e-15 55.0 3.0 1.4e-06 28.1 0.3 4.3 4 0 0 4 4 4 3 PPR repeat family PPR_1 PF12854.2 CAR28448.1 - 3.9e-05 23.0 0.1 0.73 9.3 0.1 3.8 3 0 0 3 3 3 2 PPR repeat PPR_3 PF13812.1 CAR28448.1 - 0.015 15.5 0.0 52 4.4 0.0 4.3 4 0 0 4 4 4 0 Pentatricopeptide repeat domain PPR PF01535.15 CAR28448.1 - 8.6 6.5 6.5 1.1e+02 3.1 0.3 4.6 5 0 0 5 5 5 0 PPR repeat Pil1 PF13805.1 CAR28449.1 - 2.9e-153 508.6 0.4 3.5e-153 508.4 0.3 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 PCP_red PF08369.5 CAR28449.1 - 0.0024 17.6 2.5 0.029 14.2 0.2 2.8 3 0 0 3 3 3 1 Proto-chlorophyllide reductase 57 kD subunit Pribosyltran PF00156.22 CAR28450.1 - 5.1e-16 58.5 0.0 8e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF1722 PF08349.6 CAR28450.1 - 0.0064 16.3 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1722) Med27 PF11571.3 CAR28452.1 - 0.066 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Mediator complex subunit 27 DEAD PF00270.24 CAR28453.1 - 7.8e-38 129.6 0.0 1.9e-37 128.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR28453.1 - 4.7e-21 74.4 0.0 2.7e-20 72.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CAR28453.1 - 4.7e-17 61.2 0.1 1.5e-16 59.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) UvrD-helicase PF00580.16 CAR28453.1 - 0.00099 18.4 4.5 0.016 14.5 0.0 2.3 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain ResIII PF04851.10 CAR28453.1 - 0.0013 18.5 0.0 0.0013 18.5 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PseudoU_synth_1 PF01416.15 CAR28454.1 - 6e-32 110.2 0.0 2.5e-20 72.8 0.0 2.7 2 0 0 2 2 2 2 tRNA pseudouridine synthase EAP30 PF04157.11 CAR28455.1 - 7e-52 175.7 0.0 7.8e-52 175.6 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Hat1_N PF10394.4 CAR28456.1 - 9.1e-36 123.3 3.6 9.1e-36 123.3 2.5 1.7 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.19 CAR28456.1 - 0.00045 20.1 0.0 0.0012 18.8 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CAR28456.1 - 0.0038 17.3 0.0 0.0088 16.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CAR28456.1 - 0.0059 16.7 0.0 0.017 15.2 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CAR28456.1 - 0.1 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Citrate_synt PF00285.16 CAR28458.1 - 6.5e-94 314.5 0.0 7.7e-94 314.3 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase MmgE_PrpD PF03972.9 CAR28459.1 - 5.6e-155 515.8 0.0 6.5e-155 515.6 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family PUF PF00806.14 CAR28459.1 - 0.068 12.6 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat Nic96 PF04097.9 CAR28460.1 - 2.2e-212 706.5 15.7 2.9e-212 706.1 10.9 1.2 1 0 0 1 1 1 1 Nup93/Nic96 PPI_Ypi1 PF07491.6 CAR28461.1 - 1.4e-19 69.4 14.8 4.4e-19 67.8 10.2 1.9 1 1 0 1 1 1 1 Protein phosphatase inhibitor SR-25 PF10500.4 CAR28461.1 - 3.2 7.1 18.9 5.2 6.4 12.7 1.6 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein SRP-alpha_N PF04086.8 CAR28461.1 - 4.6 6.5 11.7 2.1 7.6 6.3 1.6 1 1 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CDC45 PF02724.9 CAR28461.1 - 7.2 4.5 10.7 2.9 5.8 6.0 1.3 1 1 0 1 1 1 0 CDC45-like protein JAB PF01398.16 CAR28462.1 - 8.1e-33 112.5 0.1 8.1e-33 112.5 0.1 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 CAR28462.1 - 1.3e-24 86.4 6.2 1.3e-24 86.4 4.3 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 CAR28462.1 - 1.1e-08 34.5 0.0 1.8e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain zf-UBP PF02148.14 CAR28463.1 - 1e-09 38.3 0.4 2.1e-09 37.3 0.3 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH PF00443.24 CAR28463.1 - 1.7e-07 30.6 0.1 2.9e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_M24 PF00557.19 CAR28464.1 - 4.7e-56 189.6 0.0 6.4e-56 189.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 CAR28464.1 - 2e-25 88.7 0.0 5e-25 87.4 0.0 1.7 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain MFS_1 PF07690.11 CAR28466.1 - 1.4e-31 109.5 39.1 1.4e-31 109.5 27.1 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 CAR28466.1 - 0.0015 16.7 1.0 0.0027 15.8 0.7 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector DUF123 PF01986.11 CAR28467.1 - 0.11 12.6 0.2 0.25 11.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF123 Rad21_Rec8_N PF04825.8 CAR28468.1 - 1.7e-16 60.1 0.5 7.4e-16 58.0 0.3 1.9 1 1 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein ICL PF00463.16 CAR28469.1 - 4.8e-168 559.6 0.0 5.6e-168 559.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 CAR28469.1 - 2.7e-08 33.3 0.0 1.1e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase AAA_33 PF13671.1 CAR28471.1 - 3.4e-08 33.4 0.0 0.0017 18.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CAR28471.1 - 1.9e-07 31.9 0.0 2e-06 28.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CAR28471.1 - 1.1e-06 29.0 0.0 4.1e-05 23.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CAR28471.1 - 9.3e-05 22.4 0.0 0.00018 21.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 CAR28471.1 - 0.00047 19.3 0.0 0.00082 18.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_5 PF07728.9 CAR28471.1 - 0.00056 19.6 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CAR28471.1 - 0.00091 19.3 0.0 0.0019 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain PRK PF00485.13 CAR28471.1 - 0.0013 18.3 0.0 0.56 9.7 0.0 2.5 2 1 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.17 CAR28471.1 - 0.0013 18.8 0.0 0.0028 17.8 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NB-ARC PF00931.17 CAR28471.1 - 0.0036 16.1 0.0 0.0059 15.4 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_25 PF13481.1 CAR28471.1 - 0.0038 16.6 0.0 0.021 14.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 CAR28471.1 - 0.0051 17.1 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA PF00004.24 CAR28471.1 - 0.0055 16.9 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.5 CAR28471.1 - 0.0062 15.7 0.0 0.0097 15.1 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_28 PF13521.1 CAR28471.1 - 0.0063 16.4 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 CAR28471.1 - 0.011 14.4 0.0 0.016 13.9 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein TIP49 PF06068.8 CAR28471.1 - 0.011 14.4 0.0 0.017 13.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus APS_kinase PF01583.15 CAR28471.1 - 0.017 14.7 0.0 0.049 13.2 0.0 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF402 PF04167.8 CAR28471.1 - 0.017 14.9 0.1 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF402) ADK PF00406.17 CAR28471.1 - 0.023 14.5 0.0 0.51 10.2 0.0 2.2 2 0 0 2 2 2 0 Adenylate kinase NACHT PF05729.7 CAR28471.1 - 0.024 14.2 0.0 0.063 12.9 0.0 1.7 2 0 0 2 2 1 0 NACHT domain 6PF2K PF01591.13 CAR28471.1 - 0.037 13.0 0.0 0.062 12.3 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_24 PF13479.1 CAR28471.1 - 0.041 13.4 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 CAR28471.1 - 0.042 13.5 0.0 0.09 12.4 0.0 1.6 2 0 0 2 2 1 0 NTPase Mg_chelatase PF01078.16 CAR28471.1 - 0.042 13.0 0.0 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 CAR28471.1 - 0.044 13.3 0.0 0.096 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 CAR28471.1 - 0.044 12.6 0.0 0.073 11.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activ_2 PF14532.1 CAR28471.1 - 0.051 13.6 0.0 0.71 9.9 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain MobB PF03205.9 CAR28471.1 - 0.054 13.2 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 CAR28471.1 - 0.064 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain CPG4 PF15481.1 CAR28471.1 - 0.071 13.4 0.4 0.13 12.6 0.3 1.3 1 0 0 1 1 1 0 Chondroitin proteoglycan 4 G-alpha PF00503.15 CAR28471.1 - 0.089 11.4 0.0 0.089 11.4 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit SKI PF01202.17 CAR28471.1 - 0.095 12.5 0.0 1 9.1 0.0 2.1 2 0 0 2 2 2 0 Shikimate kinase MMR_HSR1 PF01926.18 CAR28471.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_10 PF12846.2 CAR28471.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Viral_helicase1 PF01443.13 CAR28471.1 - 0.12 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.12 CAR28471.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein ATP_bind_1 PF03029.12 CAR28471.1 - 0.14 11.6 0.0 0.38 10.2 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ArgK PF03308.11 CAR28471.1 - 0.16 10.7 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 ArgK protein PPV_E1_C PF00519.12 CAR28471.1 - 0.18 10.3 0.0 0.28 9.7 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase ETF PF01012.16 CAR28472.1 - 3.8e-34 117.7 0.7 5.8e-34 117.1 0.1 1.6 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 CAR28472.1 - 4.2e-34 116.0 0.1 1.1e-33 114.7 0.1 1.7 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Sulfate_transp PF00916.15 CAR28473.1 - 1.4e-60 204.6 8.2 2.9e-60 203.6 5.7 1.5 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CAR28473.1 - 2.1e-27 94.6 4.7 6e-27 93.1 2.6 2.4 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 CAR28473.1 - 2.9e-24 84.7 0.0 5.9e-24 83.7 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 CAR28473.1 - 0.00012 22.0 0.0 0.00033 20.6 0.0 1.7 1 1 0 1 1 1 1 STAS domain DUF1072 PF06380.6 CAR28473.1 - 0.097 12.3 9.0 0.2 11.3 1.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) Nop14 PF04147.7 CAR28474.1 - 5.5 4.7 8.8 19 2.9 0.0 2.2 2 0 0 2 2 2 0 Nop14-like family Aldo_ket_red PF00248.16 CAR28475.1 - 9.4e-65 218.2 0.0 1.2e-64 217.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CNPase PF05881.7 CAR28475.1 - 0.06 12.7 0.2 0.9 8.9 0.0 2.2 1 1 1 2 2 2 0 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) Copper-fist PF00649.13 CAR28476.1 - 3.9e-22 77.1 0.9 3.9e-22 77.1 0.7 2.3 1 1 1 2 2 2 1 Copper fist DNA binding domain Ran-binding PF05508.6 CAR28477.1 - 2.5e-109 364.8 5.9 2.5e-109 364.8 4.1 1.6 2 0 0 2 2 2 1 RanGTP-binding protein PilJ PF13675.1 CAR28477.1 - 0.0015 18.7 0.0 0.006 16.8 0.0 2.0 1 0 0 1 1 1 1 Type IV pili methyl-accepting chemotaxis transducer N-term Noelin-1 PF12308.3 CAR28477.1 - 0.036 13.8 1.0 0.13 12.0 0.2 2.1 2 0 0 2 2 2 0 Neurogenesis glycoprotein AalphaY_MDB PF04611.7 CAR28477.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region CENP-B_dimeris PF09026.5 CAR28477.1 - 0.16 12.1 5.0 0.47 10.7 3.4 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SNF2_N PF00176.18 CAR28478.1 - 1.2e-70 237.6 0.0 1.8e-70 237.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 CAR28478.1 - 3.4e-53 180.3 4.2 2.8e-52 177.3 2.4 2.2 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.26 CAR28478.1 - 1.5e-12 47.2 0.0 4.1e-12 45.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 CAR28478.1 - 9.5e-10 37.7 0.1 1.3e-08 34.0 0.1 2.8 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 CAR28478.1 - 4.6e-05 22.9 0.0 0.00011 21.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1170 PF06663.8 CAR28478.1 - 0.0038 17.1 0.5 0.95 9.3 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1170) ResIII PF04851.10 CAR28478.1 - 0.0044 16.8 0.0 0.018 14.8 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Zn_clus PF00172.13 CAR28479.1 - 0.00055 19.7 6.8 0.00087 19.1 1.0 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Yip1 PF04893.12 CAR28480.1 - 0.2 11.1 7.5 0.41 10.1 5.2 1.6 1 1 0 1 1 1 0 Yip1 domain Phos_pyr_kin PF08543.7 CAR28481.1 - 7.2e-05 22.0 0.0 9e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 CAR28481.1 - 0.00081 18.5 0.0 0.035 13.2 0.0 2.3 2 1 0 2 2 2 2 pfkB family carbohydrate kinase Vps55 PF04133.9 CAR28482.1 - 1.9e-42 143.7 4.1 2.2e-42 143.5 2.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 HSP70 PF00012.15 CAR28483.1 - 1.5e-263 875.2 13.1 1.7e-263 875.0 9.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CAR28483.1 - 9.4e-15 54.0 3.9 8.2e-13 47.6 1.1 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 CAR28483.1 - 0.0001 21.9 0.0 0.00027 20.6 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 CAR28483.1 - 0.0011 18.7 10.3 0.57 10.0 1.0 4.7 3 2 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.13 CAR28483.1 - 0.015 14.3 4.0 0.15 11.1 0.1 3.3 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase DUF2036 PF09724.4 CAR28483.1 - 0.051 12.7 1.0 0.1 11.7 0.7 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2036) DUF2797 PF10977.3 CAR28483.1 - 0.073 12.6 1.4 0.14 11.7 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) CDT1 PF08839.6 CAR28484.1 - 4.2e-05 23.5 0.9 0.00012 22.0 0.2 2.2 2 1 0 2 2 2 1 DNA replication factor CDT1 like Hydrolase PF00702.21 CAR28485.1 - 8.9e-23 81.8 0.0 4.8e-22 79.4 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CAR28485.1 - 2.2e-22 80.1 0.0 3.8e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CAR28485.1 - 1.3e-13 50.5 0.0 3.4e-13 49.1 0.0 1.7 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 CAR28485.1 - 8e-05 22.5 0.0 0.00017 21.5 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CAR28485.1 - 0.0003 20.4 0.3 0.00076 19.1 0.2 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 CAR28485.1 - 0.12 11.6 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase MCM PF00493.18 CAR28486.1 - 4.6e-128 426.6 0.1 6.2e-128 426.2 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CAR28486.1 - 1.7e-22 80.1 0.0 5.6e-22 78.4 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 CAR28486.1 - 1.8e-07 30.5 0.1 2.5e-06 26.8 0.0 2.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CAR28486.1 - 0.0061 16.0 0.0 0.015 14.7 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 CAR28486.1 - 0.011 15.2 0.0 0.026 14.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CAR28486.1 - 0.012 15.3 0.0 0.028 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) eIF-5a PF01287.15 CAR28487.1 - 1.5e-28 98.5 0.1 2.3e-28 97.9 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 CAR28487.1 - 0.00029 20.4 0.5 0.00052 19.6 0.4 1.4 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 CAR28487.1 - 0.0056 16.5 0.0 0.0088 15.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Anp1 PF03452.9 CAR28488.1 - 2.1e-114 381.2 0.0 2.1e-114 381.2 0.0 3.0 2 1 0 2 2 2 1 Anp1 UBA PF00627.26 CAR28489.1 - 8e-23 79.6 5.2 1.1e-13 50.5 0.1 3.0 3 0 0 3 3 3 2 UBA/TS-N domain ubiquitin PF00240.18 CAR28489.1 - 7.7e-15 54.0 1.3 1.6e-14 52.9 0.9 1.5 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.6 CAR28489.1 - 1.4e-14 53.2 0.3 2.9e-14 52.2 0.2 1.5 1 0 0 1 1 1 1 XPC-binding domain Rad60-SLD PF11976.3 CAR28489.1 - 5.3e-08 32.4 0.9 1.1e-07 31.4 0.6 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF1421 PF07223.6 CAR28489.1 - 0.00032 20.5 4.0 0.00032 20.5 2.8 2.2 1 1 1 2 2 1 1 Protein of unknown function (DUF1421) Rad60-SLD_2 PF13881.1 CAR28489.1 - 0.00042 20.1 0.0 0.00042 20.1 0.0 1.8 2 0 0 2 2 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CAR28489.1 - 0.00078 19.5 1.6 0.0017 18.5 1.0 1.8 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain CUE PF02845.11 CAR28489.1 - 0.041 13.3 1.9 1.5 8.3 0.0 4.3 5 1 0 5 5 5 0 CUE domain UBA_3 PF09288.5 CAR28489.1 - 0.059 12.9 0.0 2.3 7.8 0.0 2.5 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain DUF3306 PF11748.3 CAR28489.1 - 0.077 13.6 15.3 0.074 13.7 2.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) SOBP PF15279.1 CAR28489.1 - 0.19 12.0 5.7 0.23 11.8 3.9 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein MSP1_C PF07462.6 CAR28489.1 - 0.64 8.3 4.7 1.2 7.3 3.3 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus PRCC PF10253.4 CAR28489.1 - 1.4 9.5 15.6 2.3 8.8 3.4 2.3 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting TFIIA PF03153.8 CAR28489.1 - 1.7 8.4 17.7 2.6 7.8 12.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MSA-2c PF12238.3 CAR28489.1 - 2.2 7.9 19.5 0.19 11.3 3.3 2.2 2 0 0 2 2 2 0 Merozoite surface antigen 2c Asp-B-Hydro_N PF05279.6 CAR28489.1 - 6.4 6.5 9.4 12 5.6 6.5 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Epimerase PF01370.16 CAR28490.1 - 8e-22 77.8 0.0 1e-21 77.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CAR28490.1 - 5.3e-16 58.1 0.0 7.5e-16 57.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CAR28490.1 - 7.4e-12 44.7 0.1 2.4e-11 43.0 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 CAR28490.1 - 7.7e-12 45.5 0.1 1.4e-11 44.7 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 CAR28490.1 - 1.8e-08 34.5 0.0 2.9e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 CAR28490.1 - 6.8e-07 28.4 0.0 1.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 CAR28490.1 - 3.7e-05 23.4 0.0 6.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 CAR28490.1 - 0.00012 21.4 0.1 0.0003 20.1 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family Fmp27 PF10344.4 CAR28490.1 - 0.0029 15.3 0.0 0.0039 14.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 F420_oxidored PF03807.12 CAR28490.1 - 0.013 15.9 0.0 0.03 14.7 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.12 CAR28490.1 - 0.02 13.7 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Shikimate_DH PF01488.15 CAR28490.1 - 0.036 14.1 0.0 0.069 13.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.1 CAR28490.1 - 0.065 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase HAD_2 PF13419.1 CAR28491.1 - 8e-20 71.7 0.0 1.5e-19 70.8 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CAR28491.1 - 0.00047 19.8 0.0 0.0008 19.0 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like SLD3 PF08639.5 CAR28491.1 - 0.011 14.4 0.0 0.011 14.4 0.0 1.2 1 0 0 1 1 1 0 DNA replication regulator SLD3 Hydrolase PF00702.21 CAR28491.1 - 0.02 15.3 0.0 0.03 14.7 0.0 1.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Cytochrom_C PF00034.16 CAR28492.1 - 8e-10 39.4 0.1 1.4e-09 38.6 0.1 1.4 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 CAR28492.1 - 2.9e-07 30.5 2.1 2.3e-06 27.6 1.4 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 CAR28492.1 - 0.046 13.1 1.6 0.15 11.5 0.2 2.1 2 1 0 2 2 2 0 Cytochrome c-550 domain Cytochrom_C1 PF02167.10 CAR28492.1 - 0.093 12.3 0.2 0.13 11.8 0.1 1.5 1 1 0 1 1 1 0 Cytochrome C1 family Glyco_hydro_16 PF00722.16 CAR28493.1 - 3.7e-43 146.9 9.0 7.2e-43 146.0 6.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 CAR28493.1 - 0.0073 16.2 13.9 0.015 15.2 9.6 1.5 1 0 0 1 1 1 1 Chitin recognition protein NAD_kinase PF01513.16 CAR28494.1 - 3.4e-79 265.5 0.0 4.9e-79 265.0 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 CAR28494.1 - 0.047 13.1 0.1 0.42 10.0 0.0 2.3 2 1 1 3 3 3 0 Diacylglycerol kinase catalytic domain GDA1_CD39 PF01150.12 CAR28495.1 - 5.1e-117 391.0 0.0 6.5e-117 390.6 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 CAR28495.1 - 0.015 14.5 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Ppx/GppA phosphatase family Isy1 PF06246.7 CAR28496.1 - 4.5e-52 176.9 11.5 6.8e-49 166.5 4.3 2.0 1 1 1 2 2 2 2 Isy1-like splicing family Unstab_antitox PF09720.5 CAR28496.1 - 0.37 10.5 4.1 0.28 10.8 1.1 2.2 2 0 0 2 2 2 0 Putative addiction module component DUP PF00674.13 CAR28497.1 - 2.8e-06 27.2 0.3 2.8e-06 27.2 0.2 1.9 2 1 0 2 2 2 1 DUP family eIF-1a PF01176.14 CAR28497.1 - 0.11 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 CCSMST1 PF15013.1 CAR28497.1 - 1.6 8.6 3.7 0.6 10.0 0.3 1.9 2 0 0 2 2 2 0 CCSMST1 family DUP PF00674.13 CAR28498.1 - 7.3e-06 25.9 0.6 7.3e-06 25.9 0.4 2.7 2 1 1 3 3 3 1 DUP family MutS_IV PF05190.13 CAR28500.1 - 0.0076 16.3 1.6 0.2 11.8 0.0 2.9 2 0 0 2 2 2 1 MutS family domain IV Prefoldin PF02996.12 CAR28500.1 - 0.039 13.6 7.0 1.3 8.7 1.9 3.0 2 0 0 2 2 2 0 Prefoldin subunit YL1_C PF08265.6 CAR28501.1 - 2e-13 49.6 0.2 3e-13 49.0 0.1 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain RseA_C PF03873.8 CAR28501.1 - 0.0062 16.3 1.6 0.012 15.5 1.1 1.5 1 0 0 1 1 1 1 Anti sigma-E protein RseA, C-terminal domain Beta_elim_lyase PF01212.16 CAR28502.1 - 2.4e-73 246.8 0.0 3e-73 246.4 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase FAD_binding_2 PF00890.19 CAR28503.1 - 7.2e-74 249.1 0.0 8.2e-74 248.9 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 CAR28503.1 - 6.3e-09 35.2 0.0 8.6e-05 21.5 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CAR28503.1 - 1.4e-07 31.6 1.0 2.6e-05 24.1 0.1 3.0 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CAR28503.1 - 2.4e-07 30.6 0.1 1.3e-06 28.3 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CAR28503.1 - 1.1e-06 28.8 0.1 2.6e-05 24.3 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CAR28503.1 - 1.5e-06 27.5 0.2 0.00011 21.4 0.0 2.6 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 CAR28503.1 - 6e-06 25.6 0.1 1.8e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CAR28503.1 - 3.3e-05 23.1 0.2 0.002 17.2 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain Trigger_C PF05698.9 CAR28503.1 - 0.00011 22.1 1.2 0.00059 19.7 0.1 2.2 2 0 0 2 2 2 1 Bacterial trigger factor protein (TF) C-terminus GIDA PF01134.17 CAR28503.1 - 0.0012 17.8 2.2 0.043 12.6 0.0 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 CAR28503.1 - 0.0017 17.3 0.4 0.71 8.7 0.2 2.9 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 CAR28503.1 - 0.0024 17.6 0.1 0.018 14.8 0.1 2.4 1 1 0 1 1 1 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 CAR28503.1 - 0.016 13.8 0.1 0.14 10.7 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase GMC_oxred_N PF00732.14 CAR28503.1 - 0.045 12.9 1.1 0.72 8.9 0.0 2.4 2 0 0 2 2 2 0 GMC oxidoreductase Pyr_redox PF00070.22 CAR28503.1 - 0.045 14.1 0.1 20 5.6 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CAR28503.1 - 0.047 12.1 8.4 0.05 12.0 0.3 3.2 3 1 0 3 3 3 0 HI0933-like protein Sedlin_N PF04628.8 CAR28504.1 - 1.1e-12 47.9 0.2 1.3e-12 47.6 0.1 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region DUF676 PF05057.9 CAR28505.1 - 1.5e-39 135.5 0.0 2.3e-39 134.9 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 CAR28505.1 - 2.2e-05 24.4 0.0 4.2e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 CAR28505.1 - 7.6e-05 22.4 0.1 0.00022 20.9 0.0 1.7 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_5 PF12695.2 CAR28505.1 - 0.00098 18.8 0.0 0.0033 17.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 CAR28505.1 - 0.011 15.3 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Metallophos PF00149.23 CAR28507.1 - 4.3e-39 133.9 0.2 5.8e-39 133.5 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase OHCU_decarbox PF09349.5 CAR28508.1 - 1.1e-34 120.0 0.1 1.3e-34 119.8 0.1 1.0 1 0 0 1 1 1 1 OHCU decarboxylase DUF952 PF06108.7 CAR28508.1 - 0.083 12.7 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF952) DUF3631 PF12307.3 CAR28508.1 - 0.087 12.7 0.2 7.7 6.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3631) Spectrin PF00435.16 CAR28508.1 - 0.41 10.9 3.0 1.1 9.5 0.8 2.2 2 1 0 2 2 2 0 Spectrin repeat Rho_GDI PF02115.12 CAR28509.1 - 7.7e-66 221.3 1.6 9.2e-66 221.0 1.1 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor SoxY PF13501.1 CAR28509.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Sulfur oxidation protein SoxY R3H PF01424.17 CAR28510.1 - 9.7e-11 41.2 0.2 2.1e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 R3H domain SUZ PF12752.2 CAR28510.1 - 0.17 12.4 0.0 0.17 12.4 0.0 3.6 2 1 1 3 3 3 0 SUZ domain Ufd2P_core PF10408.4 CAR28511.1 - 7.5e-184 612.4 8.4 9.4e-184 612.1 5.8 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 CAR28511.1 - 1.1e-28 98.9 2.4 1.3e-28 98.7 0.5 2.0 2 0 0 2 2 2 1 U-box domain AsnC_trans_reg PF01037.16 CAR28511.1 - 0.062 13.0 0.1 6.8 6.4 0.0 2.7 2 0 0 2 2 2 0 AsnC family Ribosomal_L29 PF00831.18 CAR28512.1 - 1e-17 63.5 2.7 1e-17 63.5 1.9 2.1 2 0 0 2 2 2 1 Ribosomal L29 protein DUF4404 PF14357.1 CAR28512.1 - 0.19 12.1 2.5 0.17 12.2 0.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) DUF4600 PF15372.1 CAR28512.1 - 0.55 10.4 6.3 0.98 9.6 4.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) ERM PF00769.14 CAR28512.1 - 2.6 7.5 10.2 0.92 8.9 1.8 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Arf PF00025.16 CAR28513.1 - 2.4e-78 261.3 0.1 2.8e-78 261.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CAR28513.1 - 1.1e-14 54.2 0.0 1.1e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CAR28513.1 - 1.1e-14 54.0 0.0 1.3e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CAR28513.1 - 1.6e-11 43.5 0.7 1.5e-08 33.7 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CAR28513.1 - 2.7e-11 43.0 0.0 3.3e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CAR28513.1 - 6.7e-11 42.7 0.0 9.1e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CAR28513.1 - 4.3e-06 26.6 0.0 6.2e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CAR28513.1 - 0.0042 16.5 0.0 0.02 14.3 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRP54 PF00448.17 CAR28513.1 - 0.0054 16.1 0.2 0.011 15.1 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_33 PF13671.1 CAR28513.1 - 0.0054 16.6 0.1 0.009 15.8 0.1 1.5 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 CAR28513.1 - 0.02 14.5 0.6 2.1 7.9 0.0 2.1 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.22 CAR28513.1 - 0.021 15.0 0.1 0.046 14.0 0.1 1.6 1 1 0 1 1 1 0 ABC transporter 6PF2K PF01591.13 CAR28513.1 - 0.031 13.3 0.1 0.049 12.6 0.1 1.4 1 1 0 1 1 1 0 6-phosphofructo-2-kinase cobW PF02492.14 CAR28513.1 - 0.058 12.8 0.2 6.3 6.2 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DBD_Tnp_Mut PF03108.10 CAR28513.1 - 0.065 12.8 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 MuDR family transposase Zeta_toxin PF06414.7 CAR28513.1 - 0.14 11.2 0.1 0.33 10.0 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.1 CAR28513.1 - 0.14 12.2 0.2 0.41 10.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain Prenyltransf PF01255.14 CAR28514.1 - 7.1e-05 22.0 0.0 0.00039 19.6 0.0 1.9 2 0 0 2 2 2 1 Putative undecaprenyl diphosphate synthase Sugar_tr PF00083.19 CAR28515.1 - 1.1e-121 406.5 25.6 1.3e-121 406.3 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR28515.1 - 7.9e-18 64.2 31.8 3.3e-13 49.0 6.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pex14_N PF04695.8 CAR28515.1 - 0.00039 20.4 0.4 0.012 15.6 1.0 2.5 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Sec31 PF11549.3 CAR28516.1 - 1.8e-23 81.9 5.0 8.6e-23 79.7 3.5 2.3 1 0 0 1 1 1 1 Protein transport protein SEC31 WD40 PF00400.27 CAR28516.1 - 1.2e-15 56.7 11.2 2.5e-06 27.1 0.0 7.8 8 0 0 8 8 8 4 WD domain, G-beta repeat SRA1 PF07304.6 CAR28516.1 - 1.7e-09 37.5 0.8 7.6e-09 35.4 0.0 2.5 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 CAR28516.1 - 0.00014 21.6 0.3 0.0003 20.6 0.2 1.5 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Prp18 PF02840.10 CAR28516.1 - 0.0015 18.3 1.6 0.0032 17.2 0.1 2.2 2 1 1 3 3 3 1 Prp18 domain CHCH PF06747.8 CAR28517.1 - 0.001 18.9 5.9 0.002 17.9 4.1 1.5 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 CAR28517.1 - 3.8 7.3 7.0 0.4 10.5 1.6 1.9 2 1 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Scm3 PF10384.4 CAR28518.1 - 8.9e-23 79.5 0.8 2e-22 78.4 0.6 1.7 1 0 0 1 1 1 1 Centromere protein Scm3 Pro_isomerase PF00160.16 CAR28519.1 - 3.6e-44 150.6 0.1 6.2e-44 149.9 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 PF00515.23 CAR28519.1 - 2.4e-07 30.0 1.6 3.7e-07 29.4 0.1 2.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 CAR28519.1 - 4.2e-05 23.1 1.2 0.0052 16.3 0.2 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 CAR28519.1 - 4.8e-05 22.9 2.4 0.00038 20.1 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CAR28519.1 - 0.015 15.0 0.1 0.015 15.0 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 CAR28519.1 - 0.16 12.6 0.0 0.35 11.6 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 CAR28519.1 - 0.2 12.1 1.1 0.72 10.4 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat RNA_pol_Rpb1_1 PF04997.7 CAR28521.1 - 3.1e-121 404.7 0.1 5.6e-121 403.9 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 CAR28521.1 - 1.8e-107 358.7 0.1 3.3e-107 357.8 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 CAR28521.1 - 7.5e-73 243.9 0.4 2.7e-72 242.1 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 CAR28521.1 - 4.6e-65 218.8 0.4 1e-64 217.7 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 CAR28521.1 - 7.5e-46 155.7 0.0 2.5e-45 154.0 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 CAR28521.1 - 2e-44 150.6 2.9 4.7e-44 149.3 2.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 CAR28521.1 - 1.8e-34 117.6 0.1 5e-34 116.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 CAR28521.1 - 1.2e-15 56.0 322.1 0.11 12.6 10.1 16.1 7 1 1 16 16 16 13 RNA polymerase Rpb1 C-terminal repeat DUF4123 PF13503.1 CAR28521.1 - 0.016 15.2 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4123) BPL_N PF09825.4 CAR28522.1 - 1.7e-125 418.6 0.0 2.2e-125 418.2 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 CAR28522.1 - 9.5e-15 54.7 0.1 2.5e-14 53.3 0.1 1.8 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 CAR28522.1 - 7.6e-09 35.1 0.0 1.6e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain CDP-OH_P_transf PF01066.16 CAR28523.1 - 2.4e-16 59.8 3.9 3.6e-16 59.2 2.7 1.6 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Cpn60_TCP1 PF00118.19 CAR28524.1 - 5.2e-135 450.7 11.9 5.9e-135 450.6 8.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family D123 PF07065.9 CAR28525.1 - 2.8e-102 341.8 1.2 3.4e-102 341.5 0.8 1.0 1 0 0 1 1 1 1 D123 DUF4343 PF14243.1 CAR28525.1 - 0.014 15.2 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4343) Polysacc_syn_2C PF08485.5 CAR28525.1 - 1.4 8.4 4.0 0.51 9.8 0.6 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein C-terminal ApbA_C PF08546.6 CAR28526.1 - 1.4e-24 86.4 0.1 2.2e-24 85.8 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 CAR28526.1 - 1.9e-22 79.3 0.0 3.6e-22 78.4 0.0 1.5 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 CAR28526.1 - 0.038 13.8 0.2 0.37 10.6 0.2 2.2 2 0 0 2 2 2 0 ThiF family Glyco_hydro_16 PF00722.16 CAR28527.1 - 8e-43 145.8 0.1 1.2e-42 145.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 WAP PF00095.16 CAR28527.1 - 0.076 12.9 8.7 0.18 11.8 6.1 1.6 1 0 0 1 1 1 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' Chitin_bind_1 PF00187.14 CAR28527.1 - 0.14 12.1 13.4 0.27 11.2 9.3 1.4 1 0 0 1 1 1 0 Chitin recognition protein Ribonuclease_T2 PF00445.13 CAR28528.1 - 1.8e-42 145.1 0.4 2.9e-42 144.4 0.2 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Transp_cyt_pur PF02133.10 CAR28529.1 - 1.2e-70 238.2 31.4 1.5e-70 237.9 21.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2968 PF11180.3 CAR28530.1 - 0.023 14.0 1.6 0.023 14.0 1.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Sed5p PF11416.3 CAR28530.1 - 0.044 13.2 0.5 0.14 11.5 0.3 1.8 1 0 0 1 1 1 0 Integral membrane protein Sed5p DUF3573 PF12097.3 CAR28530.1 - 0.76 8.3 5.0 3.4 6.1 3.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) TBPIP PF07106.8 CAR28530.1 - 0.87 9.1 6.5 0.17 11.4 1.9 1.7 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 CAR28530.1 - 1.1 8.8 6.2 0.51 9.9 1.4 2.1 2 0 0 2 2 2 0 IncA protein SlyX PF04102.7 CAR28530.1 - 7.4 7.0 10.9 1.7 9.1 0.7 2.9 2 1 1 3 3 3 0 SlyX Y_phosphatase PF00102.22 CAR28531.1 - 6e-57 192.6 1.1 1.1e-55 188.5 0.8 2.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 CAR28531.1 - 0.0053 16.3 2.7 0.032 13.8 0.0 3.3 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CAR28531.1 - 0.0058 16.8 0.1 0.027 14.7 0.0 2.2 2 0 0 2 2 2 1 Tyrosine phosphatase family IBN_N PF03810.14 CAR28532.1 - 1.2e-16 60.3 0.4 4.2e-16 58.6 0.3 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain SCRL PF06876.7 CAR28532.1 - 0.068 13.1 0.2 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 Plant self-incompatibility response (SCRL) protein IstB_IS21 PF01695.12 CAR28532.1 - 0.07 12.5 0.5 0.22 10.9 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein NAPRTase PF04095.11 CAR28533.1 - 1.2e-67 227.8 0.0 1.5e-67 227.4 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family Viral_coat PF00729.13 CAR28534.1 - 0.005 16.1 0.4 0.014 14.6 0.3 1.7 1 0 0 1 1 1 1 Viral coat protein (S domain) WD40 PF00400.27 CAR28534.1 - 0.042 13.7 9.5 0.21 11.5 0.0 4.7 5 0 0 5 5 5 0 WD domain, G-beta repeat DUF3237 PF11578.3 CAR28534.1 - 0.058 12.6 0.0 0.45 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3237) RNA_pol_N PF01194.12 CAR28535.1 - 8.3e-30 102.6 0.5 9.3e-30 102.4 0.4 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 CAR28535.1 - 0.058 13.4 0.2 0.073 13.1 0.1 1.3 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) YhfH PF14149.1 CAR28535.1 - 0.068 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 YhfH-like protein Dynamin_N PF00350.18 CAR28536.1 - 5.5e-43 146.6 0.1 1.4e-42 145.3 0.1 1.8 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 CAR28536.1 - 0.00042 20.7 0.0 0.0011 19.4 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CAR28536.1 - 0.0018 18.2 0.1 0.014 15.3 0.1 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_M PF01031.15 CAR28536.1 - 0.0099 14.6 0.0 0.0099 14.6 0.0 2.7 3 0 0 3 3 3 1 Dynamin central region AKAP7_RIRII_bdg PF10470.4 CAR28536.1 - 0.017 14.9 0.1 0.084 12.7 0.1 2.2 1 0 0 1 1 1 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein AAA_16 PF13191.1 CAR28536.1 - 0.023 14.6 0.6 0.095 12.6 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain Linker_histone PF00538.14 CAR28537.1 - 4.9e-43 145.1 1.2 2.7e-22 78.6 0.1 2.3 2 0 0 2 2 2 2 linker histone H1 and H5 family DUF966 PF06136.8 CAR28537.1 - 0.059 12.7 9.8 0.072 12.5 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF3698 PF12479.3 CAR28537.1 - 2.5 8.2 8.6 3.1 7.9 1.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3698) TRF PF08558.5 CAR28538.1 - 4.2e-76 255.4 1.0 6e-76 254.9 0.7 1.1 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 CAR28538.1 - 9.2e-06 25.6 0.1 1.7e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CAR28538.1 - 0.0042 17.1 0.0 0.012 15.7 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain WD40 PF00400.27 CAR28539.1 - 3.7e-35 118.5 22.6 1.1e-06 28.2 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat YEATS PF03366.11 CAR28540.1 - 4.6e-22 77.5 0.2 9.6e-22 76.5 0.1 1.6 1 0 0 1 1 1 1 YEATS family YEATS PF03366.11 CAR28541.1 - 3.9e-24 84.1 0.1 6.2e-24 83.5 0.1 1.3 1 0 0 1 1 1 1 YEATS family RNA_pol_Rpo13 PF12136.3 CAR28542.1 - 1.1 8.9 6.8 3.1 7.5 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase Rpo13 subunit HTH domain Macoilin PF09726.4 CAR28542.1 - 2.1 6.5 18.2 2.5 6.2 12.6 1.1 1 0 0 1 1 1 0 Transmembrane protein YqeY PF09424.5 CAR28543.1 - 1.8e-22 79.7 3.1 2.6e-22 79.2 2.2 1.2 1 0 0 1 1 1 1 Yqey-like protein Pox_A3L PF05288.6 CAR28543.1 - 0.11 12.2 1.6 0.33 10.7 0.6 2.1 2 0 0 2 2 2 0 Poxvirus A3L Protein GRAB PF10375.4 CAR28544.1 - 2.7e-05 23.6 0.2 6.8e-05 22.3 0.2 1.7 1 0 0 1 1 1 1 GRIP-related Arf-binding domain CENP-F_leu_zip PF10473.4 CAR28544.1 - 5.6e-05 23.0 71.5 0.0038 17.0 12.6 4.5 1 1 3 4 4 4 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 CAR28544.1 - 8.5e-05 22.1 48.5 8.5e-05 22.1 33.6 3.0 1 1 1 2 2 2 1 Intermediate filament protein Myosin_tail_1 PF01576.14 CAR28544.1 - 0.00017 19.5 57.7 0.00023 19.0 40.0 1.1 1 0 0 1 1 1 1 Myosin tail AAA_13 PF13166.1 CAR28544.1 - 0.00027 19.5 28.6 0.00027 19.5 19.8 2.2 1 1 1 2 2 2 1 AAA domain GAS PF13851.1 CAR28544.1 - 0.00073 18.7 66.0 0.055 12.6 20.5 3.9 1 1 3 4 4 4 3 Growth-arrest specific micro-tubule binding CCDC155 PF14662.1 CAR28544.1 - 0.0042 16.7 29.5 0.0042 16.7 20.5 3.3 1 1 2 3 3 3 1 Coiled-coil region of CCDC155 zf-C4H2 PF10146.4 CAR28544.1 - 0.0056 16.7 12.7 0.0056 16.7 8.8 2.9 2 1 0 2 2 1 1 Zinc finger-containing protein TMF_TATA_bd PF12325.3 CAR28544.1 - 0.0069 16.1 64.3 0.049 13.3 10.2 5.5 1 1 3 4 4 4 3 TATA element modulatory factor 1 TATA binding Spc7 PF08317.6 CAR28544.1 - 0.014 14.1 61.0 0.01 14.4 17.3 3.4 1 1 3 4 4 4 0 Spc7 kinetochore protein DUF3584 PF12128.3 CAR28544.1 - 0.045 11.0 57.7 0.41 7.9 10.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Reo_sigmaC PF04582.7 CAR28544.1 - 0.063 12.4 24.2 0.04 13.1 5.6 3.2 1 1 4 5 5 5 0 Reovirus sigma C capsid protein WEMBL PF05701.6 CAR28544.1 - 0.084 11.3 59.1 1 7.7 30.0 3.3 1 1 1 2 2 2 0 Weak chloroplast movement under blue light ATG16 PF08614.6 CAR28544.1 - 0.14 11.9 64.1 1 9.1 7.3 4.6 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) Lebercilin PF15619.1 CAR28544.1 - 0.34 10.2 63.3 0.041 13.3 13.4 3.4 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Mnd1 PF03962.10 CAR28544.1 - 0.49 10.0 56.9 0.1 12.2 11.2 4.0 1 1 3 4 4 4 0 Mnd1 family IncA PF04156.9 CAR28544.1 - 0.57 9.7 71.8 0.16 11.5 17.7 4.0 1 1 2 3 3 3 0 IncA protein Fez1 PF06818.10 CAR28544.1 - 1.4 8.8 48.4 0.16 12.0 10.0 2.7 2 1 1 3 3 3 0 Fez1 APG6 PF04111.7 CAR28544.1 - 2.4 7.1 69.0 0.046 12.7 17.8 4.0 1 1 3 4 4 4 0 Autophagy protein Apg6 DUF4201 PF13870.1 CAR28544.1 - 7.8 5.8 63.6 0.89 8.9 7.9 3.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) ADIP PF11559.3 CAR28544.1 - 8.4 6.2 64.6 0.083 12.7 13.4 5.0 1 1 5 6 6 6 0 Afadin- and alpha -actinin-Binding EzrA PF06160.7 CAR28544.1 - 9 4.3 55.6 0.029 12.5 14.6 2.8 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA RFC1 PF08519.7 CAR28545.1 - 2.4e-60 202.8 1.0 2e-58 196.5 0.1 2.4 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain AAA PF00004.24 CAR28545.1 - 2.1e-13 50.5 0.2 1.6e-12 47.7 0.0 2.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.21 CAR28545.1 - 3.1e-11 43.2 0.0 1e-10 41.6 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Rad17 PF03215.10 CAR28545.1 - 5.1e-07 28.7 0.3 0.00037 19.3 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 CAR28545.1 - 6.3e-06 26.3 0.0 2.1e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CAR28545.1 - 6.5e-06 26.9 0.4 0.00011 23.0 0.0 3.1 4 0 0 4 4 3 1 AAA domain RuvB_N PF05496.7 CAR28545.1 - 1.8e-05 23.9 0.0 4.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 CAR28545.1 - 0.0019 18.0 0.1 0.0093 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CAR28545.1 - 0.0039 17.1 2.4 0.018 15.0 0.0 2.9 3 1 1 4 4 4 1 AAA ATPase domain AAA_24 PF13479.1 CAR28545.1 - 0.0066 16.0 0.1 0.033 13.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CAR28545.1 - 0.0073 16.4 0.0 0.025 14.7 0.0 2.0 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.1 CAR28545.1 - 0.0077 16.1 0.0 0.078 12.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CAR28545.1 - 0.0095 16.2 0.0 0.0095 16.2 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.9 CAR28545.1 - 0.025 14.3 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CAR28545.1 - 0.026 14.2 0.0 0.06 13.0 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 CAR28545.1 - 0.15 12.0 1.0 0.34 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain DPPIV_N PF00930.16 CAR28546.1 - 1.2e-88 297.1 0.1 1.6e-88 296.6 0.1 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 CAR28546.1 - 2.9e-48 163.9 1.9 4.4e-48 163.3 1.3 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CAR28546.1 - 9.6e-09 35.1 0.0 1.7e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CAR28546.1 - 2.3e-08 34.2 0.0 2.9e-07 30.5 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 CAR28546.1 - 0.00015 21.2 0.1 0.00027 20.4 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 CAR28546.1 - 0.0039 16.6 0.3 0.18 11.2 0.2 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase LIP PF03583.9 CAR28546.1 - 0.017 14.3 1.6 2.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Secretory lipase PAF-AH_p_II PF03403.8 CAR28546.1 - 0.04 12.2 0.1 0.081 11.1 0.0 1.4 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Peptidase_S15 PF02129.13 CAR28546.1 - 0.068 12.5 2.2 0.62 9.4 0.4 2.4 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Ribosomal_L18p PF00861.17 CAR28547.1 - 4.9e-45 152.5 2.0 2.4e-44 150.3 0.0 2.1 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 CAR28547.1 - 1.8e-32 111.7 6.7 1.8e-32 111.7 4.6 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.1 CAR28547.1 - 0.013 15.5 0.5 0.63 10.1 0.0 2.7 3 0 0 3 3 3 0 Threonine synthase N terminus Metal_resist PF13801.1 CAR28547.1 - 0.037 14.0 0.5 0.081 12.9 0.2 1.8 1 1 0 1 1 1 0 Heavy-metal resistance MtrA PF04208.9 CAR28547.1 - 0.058 12.8 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A GCR1_C PF12550.3 CAR28547.1 - 1.7 8.5 5.6 3.5 7.5 0.2 2.4 2 0 0 2 2 2 0 Transcriptional activator of glycolytic enzymes SPT6_acidic PF14632.1 CAR28547.1 - 9.2 6.5 12.6 64 3.8 8.7 2.2 1 1 0 1 1 1 0 Acidic N-terminal SPT6 CtaG_Cox11 PF04442.9 CAR28549.1 - 3.7e-59 198.8 0.4 5.7e-59 198.2 0.0 1.5 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Zn_clus PF00172.13 CAR28550.1 - 1.3e-05 24.9 7.6 3e-05 23.8 5.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl_transf_1 PF00698.16 CAR28551.1 - 0.0026 17.1 0.0 0.012 15.0 0.0 1.9 1 1 0 1 1 1 1 Acyl transferase domain Mito_carr PF00153.22 CAR28552.1 - 4.4e-70 231.4 0.2 1.7e-27 94.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2407_C PF13373.1 CAR28553.1 - 1.3e-45 154.7 0.5 2.4e-45 153.9 0.4 1.4 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 CAR28553.1 - 1.4e-22 79.7 0.4 2.1e-22 79.0 0.3 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2453 PF10507.4 CAR28553.1 - 0.091 12.5 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2453) RNA_pol_Rpb8 PF03870.10 CAR28554.1 - 2.4e-43 147.6 0.0 2.7e-43 147.4 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 NifU_N PF01592.11 CAR28555.1 - 6.1e-52 174.8 0.0 8e-52 174.4 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain DUF1691 PF07950.6 CAR28557.1 - 7.9e-33 112.6 1.8 6.1e-17 61.5 0.5 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Sdh_cyt PF01127.17 CAR28557.1 - 6e-08 32.5 1.2 1.3e-05 25.0 0.2 2.3 2 0 0 2 2 2 2 Succinate dehydrogenase/Fumarate reductase transmembrane subunit PHD PF00628.24 CAR28558.1 - 4.3e-12 45.5 6.4 1.4e-11 43.9 4.4 1.9 1 0 0 1 1 1 1 PHD-finger zf-RING_2 PF13639.1 CAR28558.1 - 0.4 10.5 6.1 1.6 8.5 4.2 2.1 1 0 0 1 1 1 0 Ring finger domain WD40 PF00400.27 CAR28559.1 - 8.6e-07 28.6 5.0 0.74 9.7 0.1 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat RicinB_lectin_2 PF14200.1 CAR28559.1 - 0.0099 16.2 0.1 0.026 14.8 0.1 1.8 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like CAF1C_H4-bd PF12265.3 CAR28559.1 - 0.033 14.0 0.1 0.092 12.6 0.0 1.8 1 0 0 1 1 1 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex Pkinase PF00069.20 CAR28560.1 - 4.4e-67 225.9 0.0 8.5e-67 225.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR28560.1 - 6.7e-37 126.9 0.0 1.5e-36 125.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR28560.1 - 9.4e-09 34.6 0.0 1.5e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CAR28560.1 - 0.0067 15.5 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2365 PF10157.4 CAR28560.1 - 0.058 13.2 0.2 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) APH PF01636.18 CAR28560.1 - 0.09 12.4 0.0 0.24 11.1 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CAR28560.1 - 0.12 11.1 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 GrpE PF01025.14 CAR28561.1 - 3.2e-48 163.4 9.4 4.2e-48 163.0 6.5 1.2 1 0 0 1 1 1 1 GrpE DUF812 PF05667.6 CAR28561.1 - 0.013 14.0 6.3 0.015 13.8 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) PEARLI-4 PF05278.7 CAR28561.1 - 0.016 14.6 5.4 0.024 14.0 3.7 1.2 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) IncA PF04156.9 CAR28561.1 - 0.021 14.4 6.7 0.026 14.1 4.6 1.2 1 0 0 1 1 1 0 IncA protein DUF3395 PF11875.3 CAR28561.1 - 0.11 12.1 4.8 0.14 11.7 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) TraF PF13728.1 CAR28561.1 - 0.14 11.6 7.2 0.22 10.9 5.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein V_ATPase_I PF01496.14 CAR28561.1 - 0.25 9.1 3.6 0.28 9.0 2.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Vps5 PF09325.5 CAR28561.1 - 1.2 8.3 13.7 1.4 8.0 9.0 1.4 1 1 1 2 2 2 0 Vps5 C terminal like TPD52 PF04201.10 CAR28561.1 - 2.9 7.5 9.9 6.8 6.3 6.8 1.6 1 1 0 1 1 1 0 Tumour protein D52 family Spc24 PF08286.6 CAR28561.1 - 4.6 6.9 9.3 7.8 6.2 6.4 1.4 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Pkinase PF00069.20 CAR28562.1 - 1.3e-67 227.7 0.0 2.4e-67 226.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR28562.1 - 9.4e-41 139.5 0.0 1.5e-40 138.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR28562.1 - 2.5e-07 29.9 0.0 4.2e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CAR28562.1 - 0.004 16.2 0.1 0.0092 15.0 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CAR28562.1 - 0.0072 16.0 1.5 0.0079 15.9 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CAR28562.1 - 0.044 13.1 0.2 0.092 12.0 0.2 1.5 1 0 0 1 1 1 0 RIO1 family Ribosomal_L35Ae PF01247.13 CAR28563.1 - 3e-40 135.8 0.9 3.4e-40 135.7 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 CAR28563.1 - 0.003 17.4 0.0 0.57 10.1 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain chaperone_DMP PF10448.4 CAR28564.1 - 4.2e-13 49.4 0.3 1.3e-12 47.7 0.2 1.7 1 1 0 1 1 1 1 20S proteasome chaperone TetR_C_9 PF14514.1 CAR28564.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator, TetR, C-terminal DHFR_1 PF00186.14 CAR28565.1 - 3.9e-31 107.8 0.0 5.4e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Dihydrofolate reductase Oxysterol_BP PF01237.13 CAR28566.1 - 7.6e-92 307.5 0.6 9.4e-92 307.2 0.4 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Nop53 PF07767.6 CAR28567.1 - 3.7e-81 273.1 52.9 4.2e-81 272.8 36.6 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Ipi1_N PF12333.3 CAR28567.1 - 3.8 7.5 5.7 48 3.9 1.5 3.5 2 1 1 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation ABC_membrane_2 PF06472.10 CAR28569.1 - 3.5e-84 282.2 6.4 3.5e-84 282.2 4.4 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 CAR28569.1 - 2.6e-13 50.4 0.0 8.1e-13 48.8 0.0 1.9 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.14 CAR28569.1 - 0.0013 18.0 0.4 0.45 9.7 0.0 2.5 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain DUF1749 PF08538.5 CAR28570.1 - 2e-91 306.0 0.0 2.2e-91 305.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 CAR28570.1 - 9.4e-12 45.2 0.0 1.1e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CAR28570.1 - 5.9e-08 32.5 0.0 1.9e-07 30.9 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAR28570.1 - 5.2e-06 26.1 0.0 1.3e-05 24.8 0.0 1.5 1 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CAR28570.1 - 4.1e-05 22.9 0.0 0.0027 16.9 0.0 2.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 CAR28570.1 - 0.072 12.5 0.0 0.17 11.2 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase MHC_I PF00129.13 CAR28570.1 - 0.13 11.5 0.0 0.36 10.1 0.0 1.7 2 0 0 2 2 2 0 Class I Histocompatibility antigen, domains alpha 1 and 2 Acetyltransf_1 PF00583.19 CAR28571.1 - 0.021 14.8 0.1 0.041 13.9 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family ACPS PF01648.15 CAR28572.1 - 6.7e-11 42.0 0.0 1.8e-10 40.6 0.0 1.6 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily APG5 PF04106.7 CAR28573.1 - 7e-46 156.1 0.1 9.4e-46 155.7 0.1 1.2 1 0 0 1 1 1 1 Autophagy protein Apg5 SGT1 PF07093.6 CAR28574.1 - 1.6e-44 152.3 20.0 4.3e-39 134.3 0.2 2.0 2 0 0 2 2 2 2 SGT1 protein Pkinase PF00069.20 CAR28575.1 - 2.6e-68 230.0 0.0 2.6e-68 230.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR28575.1 - 7.8e-39 133.2 0.0 1.3e-38 132.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR28575.1 - 2.3e-08 33.3 0.0 6.7e-08 31.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CAR28575.1 - 0.00039 19.5 0.2 0.047 12.7 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Mak16 PF04874.9 CAR28575.1 - 0.034 14.2 0.3 2.4 8.2 0.2 2.8 2 0 0 2 2 2 0 Mak16 protein C-terminal region APH PF01636.18 CAR28575.1 - 0.082 12.6 0.2 0.72 9.5 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Mur_ligase_M PF08245.7 CAR28576.1 - 4.8e-07 30.0 0.3 1.1e-05 25.6 0.2 2.7 1 1 0 1 1 1 1 Mur ligase middle domain UXS1_N PF11803.3 CAR28576.1 - 0.046 13.4 0.1 0.16 11.7 0.1 1.9 1 0 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal RRM_1 PF00076.17 CAR28577.1 - 0.0049 16.4 0.0 0.018 14.6 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TruD PF01142.13 CAR28578.1 - 1.1e-63 215.1 0.5 3.7e-59 200.3 0.1 3.5 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Tom5 PF10642.4 CAR28578.1 - 0.44 10.2 3.8 0.95 9.1 2.7 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase WD40 PF00400.27 CAR28579.1 - 1.9e-46 154.3 17.6 1.8e-09 37.0 0.8 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CAR28579.1 - 0.0026 15.9 5.2 1.2 7.1 0.0 4.3 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CAR28579.1 - 0.008 14.9 0.5 4 6.0 0.0 3.7 1 1 3 4 4 4 2 Nup133 N terminal like PQQ_2 PF13360.1 CAR28579.1 - 0.012 15.1 0.2 1.8 7.9 0.0 3.0 3 0 0 3 3 3 0 PQQ-like domain MOZ_SAS PF01853.13 CAR28580.1 - 8.4e-91 302.3 1.1 1.3e-90 301.7 0.8 1.3 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 CAR28580.1 - 7e-22 76.8 0.0 1.8e-21 75.6 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Peptidase_M54 PF07998.6 CAR28580.1 - 0.048 13.4 0.2 0.11 12.2 0.2 1.5 1 0 0 1 1 1 0 Peptidase family M54 Acetyltransf_1 PF00583.19 CAR28580.1 - 0.065 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family HTH_11 PF08279.7 CAR28580.1 - 0.2 11.3 2.6 0.28 10.8 0.2 2.4 2 0 0 2 2 2 0 HTH domain PTPA PF03095.10 CAR28581.1 - 2.7e-116 387.9 0.1 3.1e-116 387.7 0.1 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DAGAT PF03982.8 CAR28582.1 - 7.2e-79 264.5 0.3 4.3e-70 235.7 0.0 2.0 2 0 0 2 2 2 2 Diacylglycerol acyltransferase Pkinase PF00069.20 CAR28583.1 - 8.3e-75 251.2 0.0 1.3e-74 250.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR28583.1 - 7.4e-35 120.2 0.0 1.2e-34 119.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 CAR28583.1 - 5.1e-27 93.7 4.8 9.3e-15 54.5 0.1 3.6 4 0 0 4 4 4 2 FHA domain Kinase-like PF14531.1 CAR28583.1 - 1.3e-10 40.7 0.0 2.5e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CAR28583.1 - 7.3e-06 25.1 0.0 1.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CAR28583.1 - 8e-05 22.4 0.0 0.0051 16.5 0.0 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CAR28583.1 - 0.0049 16.2 0.0 0.0092 15.3 0.0 1.4 1 0 0 1 1 1 1 RIO1 family SbcD_C PF12320.3 CAR28583.1 - 0.41 10.7 2.7 8.4 6.5 0.2 2.8 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Asp PF00026.18 CAR28584.1 - 1.1e-107 359.9 0.0 1.3e-107 359.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CAR28584.1 - 3.4e-11 43.3 0.0 8.5e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CAR28584.1 - 0.00068 20.0 0.0 0.25 11.8 0.0 2.7 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 CAR28584.1 - 0.00072 19.1 0.0 0.0038 16.7 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Kinesin PF00225.18 CAR28585.1 - 4.3e-104 347.8 0.1 6.2e-104 347.3 0.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain CorA PF01544.13 CAR28585.1 - 0.02 13.9 1.8 0.044 12.8 1.2 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Fib_alpha PF08702.5 CAR28585.1 - 0.076 13.1 1.4 0.58 10.2 0.4 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family IncA PF04156.9 CAR28585.1 - 1 8.8 10.9 0.4 10.2 5.5 1.8 2 0 0 2 2 2 0 IncA protein Methyltransf_15 PF09445.5 CAR28586.1 - 5.6e-57 191.8 0.0 7.6e-57 191.4 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.13 CAR28586.1 - 1.6e-06 27.7 0.0 2.6e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 CAR28586.1 - 5.3e-06 26.4 0.0 7.8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAR28586.1 - 1.5e-05 24.6 0.0 5.4e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR28586.1 - 0.00021 21.8 0.0 0.00035 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 CAR28586.1 - 0.00094 18.7 0.6 0.045 13.2 0.0 2.2 1 1 1 2 2 2 1 DNA methylase CMAS PF02353.15 CAR28586.1 - 0.0011 18.0 0.0 0.0024 17.0 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 CAR28586.1 - 0.0025 18.1 0.0 0.007 16.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CAR28586.1 - 0.0066 15.8 0.0 0.024 14.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.1 CAR28586.1 - 0.019 14.6 0.0 0.034 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 CAR28586.1 - 0.021 13.5 0.0 0.035 12.7 0.0 1.3 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Ubie_methyltran PF01209.13 CAR28586.1 - 0.022 13.8 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Pet20 PF08692.5 CAR28588.1 - 5.8e-26 91.0 7.3 2.7e-15 56.5 0.0 2.9 2 1 1 3 3 3 2 Mitochondrial protein Pet20 UMPH-1 PF05822.7 CAR28588.1 - 0.025 13.9 0.1 0.048 12.9 0.1 1.4 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) LEA_3 PF03242.8 CAR28588.1 - 0.099 12.9 0.2 0.2 11.8 0.1 1.6 1 1 0 1 1 1 0 Late embryogenesis abundant protein HapK PF11639.3 CAR28589.1 - 0.036 14.6 0.4 0.062 13.9 0.2 1.5 1 1 1 2 2 2 0 REDY-like protein HapK MerB PF03243.10 CAR28589.1 - 0.12 12.1 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Alkylmercury lyase tRNA-synt_1 PF00133.17 CAR28590.1 - 1.4e-45 155.4 0.0 5.3e-38 130.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 CAR28590.1 - 4.6e-20 71.6 0.0 5.2e-10 38.5 0.0 4.3 4 0 0 4 4 4 4 tRNA synthetases class I (M) Anticodon_1 PF08264.8 CAR28590.1 - 1.5e-11 44.2 0.0 3.4e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 CAR28590.1 - 1.8e-06 27.2 0.0 3.7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Maf PF02545.9 CAR28590.1 - 0.076 12.1 0.1 0.13 11.3 0.1 1.3 1 0 0 1 1 1 0 Maf-like protein adh_short PF00106.20 CAR28591.1 - 4.4e-13 49.4 0.1 3.8e-12 46.4 0.0 2.3 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 CAR28591.1 - 0.00048 19.9 0.0 0.00083 19.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 CAR28591.1 - 0.0012 18.0 0.5 0.0093 15.1 0.4 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 CAR28591.1 - 0.0015 18.2 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CAR28591.1 - 0.041 13.3 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 CAR28591.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3661 PF12400.3 CAR28593.1 - 6e-43 146.0 3.8 9.7e-43 145.3 2.6 1.3 1 0 0 1 1 1 1 Vaculolar membrane protein HATPase_c_3 PF13589.1 CAR28595.1 - 4.1e-14 52.4 0.0 6.9e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CAR28595.1 - 8.6e-09 35.1 0.0 1.9e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 CAR28595.1 - 0.00016 21.3 0.1 0.0019 17.8 0.0 2.4 1 1 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 CAR28595.1 - 0.00061 19.2 0.0 0.0023 17.3 0.0 2.0 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain Apc5 PF12862.2 CAR28596.1 - 5.3e-28 96.7 4.1 7e-28 96.3 1.4 2.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_5 PF12688.2 CAR28596.1 - 0.14 12.1 0.4 5.8 6.9 0.0 2.6 2 0 0 2 2 2 0 Tetratrico peptide repeat Clp1 PF06807.9 CAR28597.1 - 2.7e-17 63.2 0.0 4.6e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 CAR28597.1 - 5.4e-05 22.9 0.0 0.00017 21.2 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 CAR28597.1 - 0.00053 20.0 0.0 0.00099 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.4 CAR28597.1 - 0.001 18.5 0.0 0.0025 17.3 0.0 1.6 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 CAR28597.1 - 0.004 17.9 0.0 0.011 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 CAR28597.1 - 0.0052 16.2 0.0 0.0093 15.4 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family ABC_tran PF00005.22 CAR28597.1 - 0.012 15.9 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter UDG PF03167.14 CAR28597.1 - 0.028 13.9 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 Uracil DNA glycosylase superfamily AAA_22 PF13401.1 CAR28597.1 - 0.029 14.4 0.0 0.057 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CAR28597.1 - 0.034 14.0 0.2 0.38 10.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 CAR28597.1 - 0.039 13.5 0.0 0.074 12.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DUF258 PF03193.11 CAR28597.1 - 0.048 12.8 0.0 1.2 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 CAR28597.1 - 0.048 13.8 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA PF00004.24 CAR28597.1 - 0.073 13.2 0.1 0.22 11.7 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 CAR28597.1 - 0.08 12.9 0.0 0.27 11.2 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_19 PF13245.1 CAR28597.1 - 0.084 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Miro PF08477.8 CAR28597.1 - 0.088 13.3 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AAA_18 PF13238.1 CAR28597.1 - 0.1 12.8 0.1 0.75 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Rhodanese PF00581.15 CAR28598.1 - 7.9e-18 64.8 0.0 4.5e-09 36.6 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain SET PF00856.23 CAR28599.1 - 9.4e-09 35.7 0.1 1.3e-07 32.0 0.0 2.1 2 0 0 2 2 2 1 SET domain YHS PF04945.8 CAR28599.1 - 0.06 13.2 0.2 0.16 11.8 0.2 1.6 1 0 0 1 1 1 0 YHS domain DNA_pol_B PF00136.16 CAR28601.1 - 1.1e-97 327.7 0.5 1.9e-97 326.9 0.3 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CAR28601.1 - 8e-20 70.9 0.1 7.3e-10 38.2 0.1 2.6 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 CAR28601.1 - 9.1e-14 51.2 8.9 2.2e-13 50.0 6.2 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DZR PF12773.2 CAR28601.1 - 0.49 10.2 3.2 1.2 9.0 2.2 1.6 1 0 0 1 1 1 0 Double zinc ribbon DUF2962 PF11176.3 CAR28602.1 - 5.8e-47 159.1 10.9 6.7e-47 158.9 7.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) OSTMP1 PF09777.4 CAR28602.1 - 0.095 11.8 0.2 0.14 11.2 0.1 1.5 1 1 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor Sec3-PIP2_bind PF15277.1 CAR28602.1 - 0.095 12.5 1.6 0.5 10.2 1.0 2.4 2 1 0 2 2 2 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH Mn_catalase PF05067.7 CAR28603.1 - 0.022 13.5 0.0 0.045 12.5 0.0 1.5 2 0 0 2 2 2 0 Manganese containing catalase DUF676 PF05057.9 CAR28604.1 - 6.1e-59 198.9 0.0 9.6e-59 198.3 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.10 CAR28604.1 - 0.0042 16.1 0.0 0.0075 15.2 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase PGAP1 PF07819.8 CAR28604.1 - 0.045 13.3 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein RINT1_TIP1 PF04437.8 CAR28605.1 - 3e-93 313.0 19.1 3e-93 313.0 13.2 1.9 2 0 0 2 2 2 1 RINT-1 / TIP-1 family Cast PF10174.4 CAR28606.1 - 0.0096 14.0 0.6 0.012 13.7 0.4 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Med9 PF07544.8 CAR28606.1 - 0.0099 15.5 0.6 0.11 12.1 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 RPA_interact_M PF14767.1 CAR28606.1 - 0.021 15.5 3.6 0.036 14.8 2.5 1.4 1 1 0 1 1 1 0 Replication protein A interacting middle Streptin-Immun PF11083.3 CAR28606.1 - 0.037 13.9 0.5 0.4 10.7 0.0 2.1 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein Trep_dent_lipo PF09710.5 CAR28606.1 - 0.065 11.9 0.3 0.077 11.6 0.2 1.1 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) Cortex-I_coil PF09304.5 CAR28606.1 - 0.13 12.3 1.7 0.25 11.4 0.1 1.9 1 1 1 2 2 2 0 Cortexillin I, coiled coil Spc7 PF08317.6 CAR28606.1 - 0.35 9.4 2.5 5.2 5.6 0.0 1.9 1 1 0 2 2 2 0 Spc7 kinetochore protein EMP24_GP25L PF01105.19 CAR28607.1 - 4e-06 26.6 0.1 6.4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD RNase_PH PF01138.16 CAR28608.1 - 1.2e-14 54.7 0.2 1.7e-14 54.2 0.2 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 SpoU_methylase PF00588.14 CAR28609.1 - 7.5e-26 90.7 0.0 1.5e-25 89.6 0.0 1.6 1 0 0 1 1 1 1 SpoU rRNA Methylase family PX PF00787.19 CAR28610.1 - 2.5e-22 78.8 0.4 1.6e-21 76.2 0.0 2.4 2 1 0 2 2 2 1 PX domain Vps5 PF09325.5 CAR28610.1 - 4.3e-08 32.7 12.9 1.8e-05 24.1 2.5 2.4 2 0 0 2 2 2 2 Vps5 C terminal like Lip_prot_lig_C PF10437.4 CAR28610.1 - 0.085 12.5 1.7 11 5.7 0.1 3.6 4 0 0 4 4 4 0 Bacterial lipoate protein ligase C-terminus T2SF PF00482.18 CAR28610.1 - 0.15 11.9 1.7 14 5.6 0.0 2.7 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F CCDC-167 PF15188.1 CAR28610.1 - 0.18 11.7 7.7 0.11 12.4 1.0 3.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 B-block_TFIIIC PF04182.7 CAR28610.1 - 0.28 11.0 2.1 1.1 9.1 0.0 2.8 3 0 0 3 3 3 0 B-block binding subunit of TFIIIC DUF342 PF03961.8 CAR28610.1 - 0.38 9.1 10.5 0.4 9.0 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF342) H-kinase_dim PF02895.9 CAR28610.1 - 1.5 9.2 6.4 2.6 8.4 0.0 3.6 3 1 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain adh_short PF00106.20 CAR28611.1 - 1.1e-25 90.4 0.0 2.1e-25 89.5 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CAR28611.1 - 3.1e-08 33.6 0.0 4.2e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CAR28611.1 - 1.6e-07 31.1 0.0 3.9e-06 26.6 0.0 2.6 1 1 1 2 2 2 1 KR domain Abhydrolase_3 PF07859.8 CAR28611.1 - 0.034 13.7 0.0 0.072 12.6 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF302 PF03625.9 CAR28611.1 - 0.12 11.9 0.0 2.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF302 DUF1762 PF08574.5 CAR28612.1 - 1.1e-17 64.1 16.7 1.1e-17 64.1 11.6 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1762) Ribosomal_L6 PF00347.18 CAR28613.1 - 2e-25 89.0 7.4 2.2e-12 47.2 0.4 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 PC4 PF02229.11 CAR28613.1 - 0.033 13.4 0.5 0.066 12.4 0.0 1.7 2 0 0 2 2 2 0 Transcriptional Coactivator p15 (PC4) AdoMet_MTase PF07757.8 CAR28614.1 - 4.1e-41 139.5 0.0 9e-41 138.5 0.0 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_31 PF13847.1 CAR28614.1 - 0.0073 15.9 0.1 0.017 14.7 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAR28614.1 - 0.024 14.3 0.0 0.083 12.5 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain TcdA_TcdB_pore PF12920.2 CAR28614.1 - 0.078 10.8 0.1 0.11 10.3 0.0 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain ELK PF03789.8 CAR28614.1 - 0.15 11.8 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 ELK domain Pkinase PF00069.20 CAR28615.1 - 4.6e-76 255.4 0.0 5.2e-76 255.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR28615.1 - 1e-37 129.6 0.0 1.6e-37 128.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR28615.1 - 6.6e-05 22.0 0.0 0.0001 21.3 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CAR28615.1 - 0.04 13.6 0.0 0.16 11.6 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family ApbA_C PF08546.6 CAR28617.1 - 2.5e-06 27.5 0.0 6.6e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal CENP-Q PF13094.1 CAR28617.1 - 7.3e-05 22.8 17.8 0.0008 19.4 7.9 2.7 2 0 0 2 2 2 2 CENP-Q, a CENPA-CAD centromere complex subunit Med9 PF07544.8 CAR28617.1 - 0.39 10.4 9.9 2.7 7.7 0.4 2.7 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Peptidase_C6 PF00851.13 CAR28617.1 - 0.57 8.7 2.7 0.84 8.1 1.9 1.2 1 0 0 1 1 1 0 Helper component proteinase FUSC PF04632.7 CAR28617.1 - 0.59 8.4 2.7 0.93 7.8 1.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Spc7 PF08317.6 CAR28617.1 - 1.2 7.7 12.9 0.024 13.3 2.9 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4200 PF13863.1 CAR28617.1 - 1.2 9.0 21.4 2.2 8.2 6.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) ATG16 PF08614.6 CAR28617.1 - 1.9 8.2 22.0 0.033 14.0 7.2 2.6 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) UPF0242 PF06785.6 CAR28617.1 - 2.5 6.6 8.1 4.3 5.9 5.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) NAC PF01849.13 CAR28618.1 - 8.2e-17 60.4 0.1 1.7e-16 59.4 0.1 1.6 1 0 0 1 1 1 1 NAC domain Ribosomal_60s PF00428.14 CAR28618.1 - 0.059 13.7 0.9 0.19 12.1 0.1 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein zf-C2H2_4 PF13894.1 CAR28619.1 - 4.9e-09 35.9 5.9 0.00064 19.8 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CAR28619.1 - 9.3e-09 35.1 11.0 0.00025 21.2 2.8 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CAR28619.1 - 0.0003 20.9 2.9 0.023 14.9 0.0 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CAR28619.1 - 0.006 16.6 2.5 1.5 9.0 0.0 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding RIG-I_C-RD PF11648.3 CAR28619.1 - 0.026 14.4 0.6 0.043 13.6 0.4 1.4 1 0 0 1 1 1 0 C-terminal domain of RIG-I zf-C2H2_6 PF13912.1 CAR28619.1 - 0.036 13.9 5.4 0.6 10.0 0.8 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger RRN7 PF11781.3 CAR28619.1 - 0.089 12.3 0.8 4.3 6.9 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-H2C2_5 PF13909.1 CAR28619.1 - 0.1 12.9 1.0 0.1 12.9 0.7 2.4 2 1 0 2 2 2 0 C2H2-type zinc-finger domain GAGA PF09237.6 CAR28619.1 - 0.39 10.3 2.2 0.64 9.6 0.7 1.9 2 0 0 2 2 2 0 GAGA factor zf-CCHC_5 PF14787.1 CAR28619.1 - 0.41 10.1 0.1 0.41 10.1 0.1 2.1 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger tRNA-synt_1 PF00133.17 CAR28621.1 - 2.7e-160 534.3 0.0 3.8e-160 533.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 CAR28621.1 - 8.3e-23 80.6 0.0 1.7e-11 43.4 0.0 3.7 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 CAR28621.1 - 2.7e-19 69.4 2.1 3e-19 69.2 0.3 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.9 CAR28621.1 - 0.00026 20.5 2.2 0.00026 20.5 1.6 2.1 2 0 0 2 2 2 1 Zinc finger found in FPG and IleRS STAT_alpha PF01017.15 CAR28621.1 - 0.051 13.2 0.1 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 STAT protein, all-alpha domain tRNA-synt_1_2 PF13603.1 CAR28621.1 - 0.083 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 MFS_1 PF07690.11 CAR28622.1 - 1e-30 106.6 26.1 1e-30 106.6 18.1 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily CBFD_NFYB_HMF PF00808.18 CAR28622.1 - 0.17 11.9 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2721 PF11026.3 CAR28622.1 - 0.35 10.5 0.0 0.35 10.5 0.0 3.1 5 0 0 5 5 5 0 Protein of unknown function (DUF2721) RseC_MucC PF04246.7 CAR28622.1 - 0.93 9.0 3.4 2.1 7.9 0.2 2.9 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC FLILHELTA PF10306.4 CAR28623.1 - 9.9e-24 83.1 0.0 1.8e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF2740 PF10872.3 CAR28623.1 - 0.026 14.1 0.4 0.048 13.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) Pkinase PF00069.20 CAR28624.1 - 2.1e-55 187.6 0.0 2.9e-53 180.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAR28624.1 - 2.6e-26 92.2 0.0 3.2e-25 88.6 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR28624.1 - 0.12 11.3 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RRM_1 PF00076.17 CAR28625.1 - 2.2e-60 200.1 0.5 3e-17 61.9 0.1 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR28625.1 - 6.7e-48 160.5 0.5 1.3e-13 50.7 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR28625.1 - 1.5e-18 66.4 1.6 2.7e-07 30.3 0.0 4.8 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CENP-N PF05238.8 CAR28626.1 - 5e-101 338.6 0.0 5.7e-101 338.4 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like FG-GAP_2 PF14312.1 CAR28626.1 - 0.026 14.5 0.2 0.052 13.5 0.1 1.5 1 0 0 1 1 1 0 FG-GAP repeat Vps16_C PF04840.7 CAR28627.1 - 1e-82 277.6 4.2 1.9e-82 276.7 2.9 1.3 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.8 CAR28627.1 - 2.8e-71 240.2 1.2 3.8e-71 239.7 0.9 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region Skp1_POZ PF03931.10 CAR28628.1 - 1.8e-16 59.9 0.0 1.1e-15 57.4 0.0 1.9 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.26 CAR28628.1 - 0.00092 19.1 0.0 0.0027 17.6 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain zf-RING_UBOX PF13445.1 CAR28629.1 - 1.3e-14 53.5 1.6 3.9e-14 52.0 1.1 1.9 1 0 0 1 1 1 1 RING-type zinc-finger CLTH PF10607.4 CAR28629.1 - 1.4e-11 44.3 0.8 1.4e-11 44.3 0.5 2.7 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain DegS PF05384.6 CAR28629.1 - 0.0024 17.1 3.2 0.0049 16.0 2.2 1.5 1 0 0 1 1 1 1 Sensor protein DegS zf-RING_2 PF13639.1 CAR28629.1 - 0.0095 15.7 0.8 0.023 14.5 0.5 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CAR28629.1 - 0.026 14.5 0.3 0.068 13.2 0.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAR28629.1 - 0.033 13.9 0.6 0.11 12.2 0.4 1.9 1 0 0 1 1 1 0 zinc-RING finger domain YscO PF07321.7 CAR28629.1 - 0.23 11.2 7.5 0.6 9.9 5.2 1.6 1 0 0 1 1 1 0 Type III secretion protein YscO DUF3837 PF12939.2 CAR28629.1 - 0.74 9.8 4.4 1.5 8.8 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3837) Sgf11 PF08209.6 CAR28630.1 - 1.7e-16 59.1 3.4 2.6e-16 58.6 2.3 1.3 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.1 CAR28630.1 - 0.0032 17.0 0.3 0.0048 16.5 0.2 1.3 1 0 0 1 1 1 1 zinc-finger of a C2HC-type DUF4125 PF13526.1 CAR28630.1 - 0.018 14.5 0.0 0.018 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4125) zf-U11-48K PF05253.7 CAR28630.1 - 0.019 14.6 0.0 4.2 7.1 0.0 2.4 2 0 0 2 2 2 0 U11-48K-like CHHC zinc finger Catalase PF00199.14 CAR28631.1 - 1.5e-171 570.3 1.2 1.9e-171 569.9 0.8 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 CAR28631.1 - 1.7e-11 43.8 0.2 8.9e-11 41.4 0.0 2.2 2 0 0 2 2 2 1 Catalase-related immune-responsive EF1G PF00647.14 CAR28632.1 - 2.1e-43 146.3 0.1 3.5e-43 145.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 CAR28632.1 - 4.6e-10 39.3 0.0 1.5e-09 37.6 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CAR28632.1 - 1.1e-06 28.4 0.0 2.2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CAR28632.1 - 5.8e-06 26.3 2.4 9.6e-06 25.6 0.0 2.5 3 1 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CAR28632.1 - 0.0041 17.5 0.0 0.0086 16.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Anp1 PF03452.9 CAR28634.1 - 6.7e-108 359.9 0.1 8.1e-108 359.6 0.1 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 CAR28634.1 - 0.00065 19.4 0.2 0.0016 18.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Alk_phosphatase PF00245.15 CAR28635.1 - 4.5e-126 420.9 0.1 5.3e-126 420.6 0.1 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 CAR28635.1 - 0.00019 20.8 0.0 0.00039 19.8 0.0 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily Arf PF00025.16 CAR28636.1 - 2.4e-48 163.6 0.1 3.1e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CAR28636.1 - 7.9e-15 54.6 0.0 9.3e-15 54.3 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CAR28636.1 - 1.1e-13 50.8 0.0 3e-13 49.3 0.0 1.5 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit Miro PF08477.8 CAR28636.1 - 1.1e-12 48.4 0.0 1.5e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 CAR28636.1 - 2e-10 40.1 0.0 2.4e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 CAR28636.1 - 4.9e-10 38.6 0.8 2.3e-06 26.5 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit GTP_EFTU PF00009.22 CAR28636.1 - 1e-09 38.1 0.0 6.2e-09 35.5 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CAR28636.1 - 4.9e-07 29.7 0.0 8e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CAR28636.1 - 0.0013 18.8 0.1 0.0066 16.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 CAR28636.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase Septin PF00735.13 CAR28636.1 - 0.14 11.1 0.2 0.36 9.8 0.0 1.6 2 0 0 2 2 2 0 Septin cwf21 PF08312.7 CAR28637.1 - 4.6e-15 55.2 5.2 7e-15 54.6 3.6 1.3 1 0 0 1 1 1 1 cwf21 domain LUC7 PF03194.10 CAR28637.1 - 0.012 15.1 3.2 0.014 14.9 2.2 1.0 1 0 0 1 1 1 0 LUC7 N_terminus Mnd1 PF03962.10 CAR28637.1 - 0.053 13.1 2.9 0.067 12.8 2.0 1.1 1 0 0 1 1 1 0 Mnd1 family Trans_reg_C PF00486.23 CAR28637.1 - 0.058 13.3 0.6 0.46 10.4 0.4 2.0 1 1 0 1 1 1 0 Transcriptional regulatory protein, C terminal DUF3835 PF12927.2 CAR28637.1 - 0.16 12.9 4.7 3.1 8.8 0.3 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF3835) ODC_AZ PF02100.12 CAR28638.1 - 2.5e-06 26.9 0.0 5.1e-06 25.9 0.0 1.4 1 1 0 1 1 1 1 Ornithine decarboxylase antizyme Glyco_transf_15 PF01793.11 CAR28639.1 - 5.8e-139 462.6 22.3 7.5e-139 462.2 15.4 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase TPR_11 PF13414.1 CAR28640.1 - 2.8e-17 62.1 9.0 3e-12 46.0 1.9 2.6 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 CAR28640.1 - 1e-11 43.9 12.4 0.00066 19.1 0.3 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CAR28640.1 - 2.6e-10 39.4 10.2 0.0022 17.7 0.3 3.9 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 CAR28640.1 - 6.2e-09 35.6 1.0 0.00068 19.5 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 CAR28640.1 - 5.3e-07 30.1 0.2 0.011 16.4 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 CAR28640.1 - 1.5e-06 28.2 9.2 7.5e-06 25.9 4.3 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 CAR28640.1 - 1.7e-06 27.8 4.4 0.00049 19.9 0.1 4.0 4 1 1 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.1 CAR28640.1 - 7.5e-06 26.1 0.4 0.0011 19.2 0.0 2.7 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 CAR28640.1 - 0.00014 21.7 2.6 0.00071 19.5 0.7 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 CAR28640.1 - 0.0016 18.9 0.0 2.6 8.9 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 CAR28640.1 - 0.003 17.2 8.3 0.2 11.5 0.3 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat DUF4162 PF13732.1 CAR28640.1 - 0.015 15.7 3.0 1.5 9.3 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4162) ThiS PF02597.15 CAR28640.1 - 0.18 12.2 0.9 1.5 9.3 0.0 2.8 3 1 0 3 3 3 0 ThiS family TPR_6 PF13174.1 CAR28640.1 - 0.38 11.3 4.7 1.3 9.6 0.1 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat INCENP_ARK-bind PF03941.10 CAR28641.1 - 1.5e-18 66.3 0.3 5.1e-18 64.6 0.2 1.9 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region Borrelia_P83 PF05262.6 CAR28641.1 - 6.1 4.9 12.7 9.3 4.3 8.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein zf-CCCH PF00642.19 CAR28643.1 - 7.1e-10 38.3 11.1 7.6e-05 22.2 1.7 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) GCIP PF13324.1 CAR28643.1 - 0.14 11.3 0.1 0.28 10.3 0.1 1.4 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting zf-CCCH_2 PF14608.1 CAR28643.1 - 0.35 10.9 11.4 0.95 9.5 1.7 2.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type LRR_4 PF12799.2 CAR28644.1 - 2.5e-05 23.8 9.3 0.31 10.7 0.9 4.6 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CAR28644.1 - 0.00089 19.0 6.2 3 8.1 0.0 5.3 5 0 0 5 5 5 2 Leucine Rich repeat LRR_7 PF13504.1 CAR28644.1 - 0.024 14.7 6.3 51 4.7 0.0 5.8 6 0 0 6 6 6 0 Leucine rich repeat LRR_1 PF00560.28 CAR28644.1 - 0.045 13.7 2.9 40 4.8 0.0 4.6 4 1 1 5 5 5 0 Leucine Rich Repeat Lge1 PF11488.3 CAR28645.1 - 1.2e-22 79.8 1.8 2.1e-22 79.0 1.2 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein LGE1 adh_short PF00106.20 CAR28646.1 - 1.2e-20 74.0 0.0 1.8e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CAR28646.1 - 9.8e-08 32.0 0.1 1.5e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CAR28646.1 - 6.9e-07 29.0 0.0 1.5e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 CAR28646.1 - 0.0022 16.9 0.1 0.003 16.4 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 CAR28646.1 - 0.038 13.9 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Pkinase PF00069.20 CAR28647.1 - 4.7e-72 242.2 0.0 5.4e-72 242.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR28647.1 - 1.2e-33 116.2 0.0 1.5e-33 115.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR28647.1 - 3.7e-06 26.1 0.0 6.1e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CAR28647.1 - 0.0091 15.7 0.3 0.043 13.5 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CAR28647.1 - 0.034 13.1 0.1 0.097 11.7 0.1 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Gly_transf_sug PF04488.10 CAR28648.1 - 3e-19 69.3 0.0 5.7e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 CAR28648.1 - 0.026 13.0 2.0 0.73 8.2 0.2 2.3 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain DUF2401 PF10287.4 CAR28649.1 - 3.3e-101 337.6 2.9 3.3e-101 337.6 2.0 1.7 2 0 0 2 2 2 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 CAR28649.1 - 8e-29 99.5 0.1 3.8e-28 97.4 0.1 2.3 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) Sporozoite_P67 PF05642.6 CAR28649.1 - 0.085 10.7 28.0 0.13 10.1 19.4 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ABC2_membrane PF01061.19 CAR28650.1 - 5.3e-71 238.1 55.5 6.3e-40 136.5 10.7 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 CAR28650.1 - 2.5e-35 121.7 0.0 3.6e-17 62.9 0.0 2.6 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 CAR28650.1 - 5.5e-34 115.9 2.5 3.6e-27 94.0 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 CAR28650.1 - 2.1e-09 36.8 25.5 2.9e-07 29.8 0.6 2.9 2 2 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 CAR28650.1 - 8.7e-08 32.1 0.0 1.8e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 CAR28650.1 - 6.7e-07 28.6 0.0 0.00036 19.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 CAR28650.1 - 4.2e-05 23.0 0.0 0.011 15.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 CAR28650.1 - 4.6e-05 22.7 0.0 0.27 10.4 0.0 3.1 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CAR28650.1 - 0.00012 21.4 0.4 0.015 14.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CAR28650.1 - 0.00039 20.5 0.1 0.048 13.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CAR28650.1 - 0.0005 20.1 0.1 0.11 12.4 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 CAR28650.1 - 0.0013 19.5 0.0 0.25 12.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CAR28650.1 - 0.0018 17.9 0.3 0.11 12.2 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 CAR28650.1 - 0.0019 18.4 0.0 0.34 11.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 CAR28650.1 - 0.0024 17.4 0.5 0.048 13.2 0.2 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 MMR_HSR1 PF01926.18 CAR28650.1 - 0.0029 17.5 0.0 1.4 8.8 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 CAR28650.1 - 0.0052 15.8 0.0 1.9 7.5 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.7 CAR28650.1 - 0.0053 16.4 0.0 0.085 12.5 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_10 PF12846.2 CAR28650.1 - 0.0069 15.8 0.5 4.2 6.7 0.2 2.9 3 0 0 3 3 3 1 AAA-like domain cobW PF02492.14 CAR28650.1 - 0.0073 15.7 0.5 0.053 12.9 0.2 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 CAR28650.1 - 0.013 15.1 0.0 17 5.0 0.0 3.2 3 0 0 3 3 3 0 NTPase AAA_21 PF13304.1 CAR28650.1 - 0.015 15.3 0.0 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CAR28650.1 - 0.036 13.9 0.0 0.84 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 CAR28650.1 - 0.047 13.1 0.2 1.2 8.6 0.2 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 CAR28650.1 - 0.052 13.7 0.0 3 8.0 0.0 2.8 2 0 0 2 2 2 0 RNA helicase SbcCD_C PF13558.1 CAR28650.1 - 0.062 13.2 0.1 3.1 7.7 0.0 3.1 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 CAR28650.1 - 0.09 12.3 0.2 2.5 7.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 CAR28650.1 - 0.16 10.8 0.0 3.7 6.3 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_15 PF13175.1 CAR28650.1 - 0.36 9.8 0.0 1.5 7.8 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain ABC2_membrane PF01061.19 CAR28651.1 - 3.3e-70 235.5 51.5 2.5e-38 131.3 8.0 3.0 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 CAR28651.1 - 2.2e-37 126.8 2.0 7.7e-30 102.6 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 CAR28651.1 - 8e-36 123.3 0.0 5.2e-17 62.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 CAR28651.1 - 8.5e-07 28.9 0.0 1.9e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 CAR28651.1 - 1.5e-06 27.5 0.0 0.00036 19.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 CAR28651.1 - 4.2e-06 26.2 0.1 0.011 15.1 0.0 2.7 3 0 0 3 3 2 2 AAA domain SMC_N PF02463.14 CAR28651.1 - 1.7e-05 24.1 0.0 0.1 11.8 0.0 3.1 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.2 CAR28651.1 - 7e-05 22.0 5.0 7e-05 22.0 3.5 2.9 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_29 PF13555.1 CAR28651.1 - 0.00012 21.5 0.2 0.015 14.8 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 CAR28651.1 - 0.0004 20.4 0.1 0.11 12.4 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CAR28651.1 - 0.00076 19.6 0.1 0.048 13.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 CAR28651.1 - 0.0026 17.4 0.0 0.085 12.5 0.0 2.4 2 0 0 2 2 2 1 NACHT domain MMR_HSR1 PF01926.18 CAR28651.1 - 0.003 17.5 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_19 PF13245.1 CAR28651.1 - 0.0038 16.9 0.1 0.11 12.2 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain UPF0079 PF02367.12 CAR28651.1 - 0.0062 16.1 0.7 0.048 13.2 0.2 2.2 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 CAR28651.1 - 0.0074 15.4 0.0 1.9 7.5 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.1 CAR28651.1 - 0.0079 16.5 0.0 0.34 11.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CAR28651.1 - 0.0085 16.9 0.0 0.25 12.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 CAR28651.1 - 0.0094 15.4 0.6 0.053 12.9 0.2 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.1 CAR28651.1 - 0.015 15.3 0.0 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 CAR28651.1 - 0.019 14.6 0.1 17 5.0 0.0 3.2 3 0 0 3 3 3 0 NTPase SbcCD_C PF13558.1 CAR28651.1 - 0.022 14.6 0.3 3.1 7.7 0.0 3.4 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 CAR28651.1 - 0.024 14.7 0.0 3 8.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.1 CAR28651.1 - 0.029 14.2 0.0 0.84 9.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CAR28651.1 - 0.033 13.6 0.3 4.2 6.7 0.2 2.9 3 0 0 3 3 3 0 AAA-like domain PduV-EutP PF10662.4 CAR28651.1 - 0.037 13.5 0.4 1.2 8.6 0.2 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Tom22 PF04281.8 CAR28651.1 - 0.062 12.8 0.9 0.12 11.8 0.6 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 T2SE PF00437.15 CAR28651.1 - 0.26 10.1 0.0 3.8 6.3 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.1 CAR28651.1 - 0.4 10.2 3.1 2.5 7.6 0.1 2.8 3 0 0 3 3 3 0 AAA domain Exo5 PF09810.4 CAR28652.1 - 3.1e-31 108.8 0.0 1.7e-30 106.3 0.0 2.0 1 1 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease DUF3271 PF11675.3 CAR28652.1 - 0.02 14.0 1.9 0.16 11.1 0.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3271) PDDEXK_1 PF12705.2 CAR28652.1 - 0.17 11.2 2.6 14 5.0 0.0 2.5 2 1 0 2 2 2 0 PD-(D/E)XK nuclease superfamily Glutaredoxin PF00462.19 CAR28653.1 - 1.9e-18 66.1 0.0 4.5e-18 64.9 0.0 1.6 2 0 0 2 2 2 1 Glutaredoxin Amidase PF01425.16 CAR28654.1 - 8.3e-92 308.3 0.0 1.2e-91 307.8 0.0 1.2 1 0 0 1 1 1 1 Amidase AHS2 PF02626.10 CAR28654.1 - 1.8e-85 286.5 0.0 2.9e-85 285.8 0.0 1.3 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 CAR28654.1 - 3.5e-63 212.6 0.0 1.5e-62 210.6 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain AHS1 PF02682.11 CAR28654.1 - 6.2e-44 149.8 0.0 1.2e-43 148.9 0.0 1.5 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 CPSase_L_chain PF00289.17 CAR28654.1 - 2.9e-37 127.1 0.0 2.1e-36 124.3 0.0 2.5 3 0 0 3 3 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CAR28654.1 - 1.6e-33 114.8 0.1 6.5e-33 112.9 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 CAR28654.1 - 1.1e-18 66.6 2.3 1.6e-18 66.1 0.4 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 CAR28654.1 - 1.9e-18 66.8 0.0 6.1e-18 65.2 0.0 1.8 2 0 0 2 2 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CAR28654.1 - 2.2e-10 40.2 0.0 4.4e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.6 CAR28654.1 - 2.2e-05 24.0 0.0 0.00013 21.4 0.0 2.2 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp PF02222.17 CAR28654.1 - 0.00012 21.5 0.0 0.00024 20.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 CAR28654.1 - 0.0012 18.5 4.7 0.037 13.7 0.2 2.9 2 1 1 3 3 2 1 Biotin-lipoyl like ATP-grasp_3 PF02655.9 CAR28654.1 - 0.0017 18.2 0.0 0.0036 17.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.1 CAR28654.1 - 0.0021 17.7 0.1 0.016 14.8 0.0 2.3 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain HlyD_3 PF13437.1 CAR28654.1 - 0.022 15.1 0.0 0.11 12.8 0.1 2.2 2 0 0 2 2 2 0 HlyD family secretion protein HlyD PF00529.15 CAR28654.1 - 0.11 11.8 0.3 0.89 8.8 0.0 2.1 2 0 0 2 2 2 0 HlyD family secretion protein GCV_H PF01597.14 CAR28654.1 - 0.11 12.1 1.7 1.7 8.3 0.1 2.8 3 0 0 3 3 2 0 Glycine cleavage H-protein ATP-grasp_5 PF13549.1 CAR28654.1 - 0.21 10.7 0.0 0.45 9.6 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain 5-nucleotidase PF06189.7 CAR28654.1 - 0.24 10.1 0.0 0.4 9.4 0.0 1.2 1 0 0 1 1 1 0 5'-nucleotidase FTR1 PF03239.9 CAR28655.1 - 8.8e-95 317.1 5.2 1e-94 316.9 3.6 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family OppC_N PF12911.2 CAR28655.1 - 1 8.7 5.7 16 4.9 0.0 3.6 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C CorA PF01544.13 CAR28656.1 - 5e-06 25.7 8.6 1.2e-05 24.4 5.9 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Glyco_transf_15 PF01793.11 CAR28657.1 - 1.1e-138 461.7 8.7 1.3e-138 461.4 6.1 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF4131 PF13567.1 CAR28657.1 - 0.099 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Abhydrolase_6 PF12697.2 CAR28658.1 - 1.7e-26 93.5 0.0 2.2e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAR28658.1 - 1.4e-19 70.5 0.0 1.8e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CAR28658.1 - 1.4e-16 60.5 0.0 3.1e-16 59.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 CAR28658.1 - 9.8e-08 31.7 0.3 2.1e-07 30.6 0.2 1.5 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Ser_hydrolase PF06821.8 CAR28658.1 - 1.5e-05 24.6 0.0 3.9e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Serine hydrolase DUF1749 PF08538.5 CAR28658.1 - 2e-05 23.6 0.0 0.00028 19.8 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1749) PGAP1 PF07819.8 CAR28658.1 - 5.1e-05 22.9 0.1 0.00061 19.4 0.1 2.1 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_2 PF02230.11 CAR28658.1 - 5.3e-05 22.7 0.0 0.58 9.5 0.0 3.0 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase LCAT PF02450.10 CAR28658.1 - 0.00023 20.2 0.0 0.00036 19.6 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.3 CAR28658.1 - 0.00041 20.1 0.0 0.00083 19.1 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 CAR28658.1 - 0.0017 18.2 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein DUF915 PF06028.6 CAR28658.1 - 0.0035 16.4 0.0 0.052 12.6 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.20 CAR28658.1 - 0.0052 16.4 0.0 0.0094 15.5 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF900 PF05990.7 CAR28658.1 - 0.0087 15.4 0.1 0.027 13.7 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Peptidase_S9 PF00326.16 CAR28658.1 - 0.032 13.4 0.0 0.84 8.8 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ndr PF03096.9 CAR28658.1 - 0.043 12.2 0.1 0.23 9.8 0.1 1.9 1 1 0 1 1 1 0 Ndr family Thioesterase PF00975.15 CAR28658.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.8 CAR28658.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold NAD_binding_6 PF08030.7 CAR28659.1 - 2.1e-20 73.2 0.9 4.9e-20 72.0 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 CAR28659.1 - 3.3e-19 69.2 16.5 6.4e-18 65.0 9.8 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 CAR28659.1 - 1.2e-13 50.8 0.0 2.7e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Costars PF14705.1 CAR28659.1 - 0.11 12.4 0.1 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Costars MnhB PF04039.8 CAR28659.1 - 0.2 11.6 4.2 0.14 12.1 1.4 1.9 2 0 0 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter PRANC PF09372.5 CAR28660.1 - 0.0004 20.3 0.1 0.0004 20.3 0.1 2.6 3 0 0 3 3 3 1 PRANC domain F-box-like PF12937.2 CAR28660.1 - 0.00097 18.8 0.2 0.0036 16.9 0.0 2.1 2 0 0 2 2 2 1 F-box-like Macoilin PF09726.4 CAR28660.1 - 1 7.5 8.7 1.8 6.7 6.0 1.5 1 0 0 1 1 1 0 Transmembrane protein NIF PF03031.13 CAR28661.1 - 1.1e-40 138.9 0.0 1.7e-40 138.2 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase NeA_P2 PF12312.3 CAR28661.1 - 0.083 12.1 0.4 0.15 11.2 0.3 1.4 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein CTI PF06934.6 CAR28661.1 - 0.088 11.0 7.3 0.017 13.3 2.9 1.4 2 0 0 2 2 2 0 Fatty acid cis/trans isomerase (CTI) DUF1764 PF08576.5 CAR28661.1 - 2.1 9.1 11.5 0.68 10.7 0.5 2.8 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Pro_isomerase PF00160.16 CAR28662.1 - 1.6e-05 25.1 0.0 5.4e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.20 CAR28663.1 - 2e-40 138.6 0.0 1.7e-39 135.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR28663.1 - 4.7e-10 38.9 0.1 1.9e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.17 CAR28663.1 - 0.13 11.5 0.5 1.3 8.3 0.4 2.1 1 1 0 1 1 1 0 RIO1 family VPS28 PF03997.7 CAR28664.1 - 1.9e-48 164.5 0.0 4.2e-47 160.2 0.0 2.0 1 1 0 1 1 1 1 VPS28 protein YwqJ-deaminase PF14431.1 CAR28664.1 - 0.091 12.6 0.0 0.29 11.0 0.0 1.8 1 1 1 2 2 2 0 YwqJ-like deaminase MCM PF00493.18 CAR28666.1 - 2.6e-133 443.9 0.1 3.1e-132 440.3 0.0 2.1 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 CAR28666.1 - 5e-28 98.0 0.1 3.3e-27 95.3 0.0 2.4 1 1 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 CAR28666.1 - 2.5e-07 30.0 0.0 3e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CAR28666.1 - 2.3e-05 24.1 0.0 8.3e-05 22.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 CAR28666.1 - 0.001 19.4 0.2 0.0043 17.4 0.1 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI YuzL PF14115.1 CAR28666.1 - 0.1 12.9 0.2 0.22 11.7 0.2 1.6 1 0 0 1 1 1 0 YuzL-like protein NUP PF06516.6 CAR28667.1 - 3.9e-110 367.5 1.0 5.6e-110 367.0 0.7 1.2 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) WD40 PF00400.27 CAR28668.1 - 1.5e-33 113.4 27.8 1.8e-06 27.5 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat PQQ_3 PF13570.1 CAR28668.1 - 0.00083 19.5 0.3 0.69 10.2 0.0 3.4 3 0 0 3 3 3 2 PQQ-like domain Nup160 PF11715.3 CAR28668.1 - 0.0087 14.2 3.6 0.13 10.3 0.2 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 DUF3312 PF11768.3 CAR28668.1 - 0.025 12.8 0.0 0.044 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) V_ATPase_I PF01496.14 CAR28669.1 - 6.9e-281 933.5 0.1 8.5e-281 933.2 0.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family TRAP_alpha PF03896.11 CAR28669.1 - 0.028 13.4 0.0 0.054 12.4 0.0 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2457 PF10446.4 CAR28669.1 - 1.4 7.5 2.7 2 7.0 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) GHMP_kinases_N PF00288.21 CAR28670.1 - 5.3e-23 80.8 0.2 1.4e-22 79.5 0.2 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CAR28670.1 - 3.7e-06 27.0 0.0 1.2e-05 25.4 0.0 1.9 1 1 1 2 2 2 1 GHMP kinases C terminal Mtc PF03820.12 CAR28671.1 - 1.7e-116 388.2 0.1 1.9e-116 388.0 0.1 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier WD40 PF00400.27 CAR28672.1 - 1.8e-32 110.0 9.1 6.7e-07 28.9 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat NLE PF08154.7 CAR28672.1 - 1.1e-23 82.9 0.2 2.1e-23 82.0 0.1 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 CAR28672.1 - 1.9e-05 22.9 7.1 0.018 13.2 0.8 3.4 2 2 1 3 3 3 3 Nucleoporin Nup120/160 N2227 PF07942.7 CAR28673.1 - 5.3e-61 205.9 0.0 8.1e-61 205.3 0.0 1.3 1 0 0 1 1 1 1 N2227-like protein Methyltransf_18 PF12847.2 CAR28673.1 - 0.077 13.5 0.0 0.2 12.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Tubulin_3 PF14881.1 CAR28674.1 - 1.4e-19 70.2 0.2 2.6e-19 69.4 0.1 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 CAR28674.1 - 5.7e-17 61.8 0.3 1.1e-16 60.8 0.2 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 CAR28674.1 - 6.1e-06 26.2 0.0 0.00013 21.8 0.0 2.3 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain IPPT PF01715.12 CAR28675.1 - 2e-83 279.3 2.0 2.7e-83 278.8 1.4 1.1 1 0 0 1 1 1 1 IPP transferase AAA_17 PF13207.1 CAR28675.1 - 2.2e-07 31.6 1.3 1.1e-06 29.4 0.7 2.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CAR28675.1 - 8.9e-07 29.2 0.6 1.1e-05 25.7 0.1 2.7 1 1 1 2 2 2 1 AAA domain IPT PF01745.11 CAR28675.1 - 4.8e-06 25.9 1.1 0.00041 19.6 0.0 3.1 2 1 1 3 3 3 1 Isopentenyl transferase AAA_33 PF13671.1 CAR28675.1 - 0.00023 21.0 0.0 0.0011 18.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CAR28675.1 - 0.0062 15.9 0.0 0.017 14.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CAR28675.1 - 0.022 13.8 0.0 0.059 12.4 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.22 CAR28675.1 - 0.026 14.8 0.2 0.13 12.5 0.0 2.2 2 1 0 2 2 2 0 ABC transporter DUF258 PF03193.11 CAR28675.1 - 0.028 13.6 0.0 0.076 12.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Hpr_kinase_C PF07475.7 CAR28675.1 - 0.032 13.5 0.0 0.071 12.4 0.0 1.5 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain SKI PF01202.17 CAR28675.1 - 0.033 14.0 0.3 3 7.6 0.0 3.0 3 0 0 3 3 3 0 Shikimate kinase AAA_14 PF13173.1 CAR28675.1 - 0.052 13.4 0.6 0.3 10.9 0.0 2.5 3 1 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 CAR28675.1 - 0.073 13.2 0.3 0.21 11.7 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_22 PF13401.1 CAR28675.1 - 0.085 13.0 0.2 1.6 8.8 0.0 2.6 2 1 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.20 CAR28675.1 - 0.16 11.4 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain CbiA PF01656.18 CAR28675.1 - 0.18 11.2 1.5 0.39 10.0 0.3 2.1 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain zf-C2H2_jaz PF12171.3 CAR28675.1 - 0.87 9.8 3.2 1.5 9.1 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding BRO1 PF03097.13 CAR28676.1 - 2.7e-83 279.8 1.1 5.1e-83 278.8 0.8 1.5 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 CAR28676.1 - 9.1e-34 116.7 17.3 3.7e-33 114.7 9.5 2.7 2 1 0 2 2 2 1 ALIX V-shaped domain binding to HIV CTD_bind PF04818.8 CAR28677.1 - 0.028 14.6 0.3 0.12 12.6 0.2 2.1 1 0 0 1 1 1 0 RNA polymerase II-binding domain. Noelin-1 PF12308.3 CAR28677.1 - 0.32 10.8 2.5 1.8 8.4 0.0 2.9 3 0 0 3 3 3 0 Neurogenesis glycoprotein Myb_DNA-binding PF00249.26 CAR28678.1 - 3.4e-20 71.8 0.4 2e-09 37.3 0.2 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CAR28678.1 - 4.8e-19 68.2 2.6 1.9e-11 43.8 0.8 3.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_Cef PF11831.3 CAR28678.1 - 3.5e-07 29.6 4.0 3.5e-07 29.6 2.8 2.6 2 1 0 2 2 2 1 pre-mRNA splicing factor component Glycos_transf_3 PF00591.16 CAR28679.1 - 3.3e-84 282.2 0.0 4.5e-84 281.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 CAR28679.1 - 5e-14 51.6 0.0 1.1e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain GAS PF13851.1 CAR28680.1 - 0.002 17.3 9.4 0.002 17.3 6.5 6.4 1 1 5 6 6 6 2 Growth-arrest specific micro-tubule binding Microtub_assoc PF07989.6 CAR28680.1 - 0.0095 15.7 4.6 0.0095 15.7 3.2 8.2 4 2 5 10 10 10 1 Microtubule associated bZIP_1 PF00170.16 CAR28680.1 - 0.03 14.2 0.9 0.03 14.2 0.6 10.8 8 3 5 13 13 13 0 bZIP transcription factor ATG16 PF08614.6 CAR28680.1 - 0.11 12.2 108.5 0.16 11.8 10.5 6.1 1 1 4 6 6 6 0 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 CAR28680.1 - 0.84 8.7 30.1 0.16 11.1 2.8 4.1 2 1 3 5 5 5 0 Reovirus sigma C capsid protein DUF1978 PF09321.5 CAR28681.1 - 0.0045 16.4 0.6 0.0049 16.3 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1978) DDRGK PF09756.4 CAR28681.1 - 0.016 14.6 0.4 0.023 14.1 0.2 1.4 1 1 0 1 1 1 0 DDRGK domain AAA_32 PF13654.1 CAR28681.1 - 0.075 11.6 0.3 0.079 11.5 0.2 1.0 1 0 0 1 1 1 0 AAA domain DUF759 PF05537.6 CAR28681.1 - 0.09 11.5 0.7 0.098 11.4 0.5 1.0 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) Rep_2 PF01719.12 CAR28681.1 - 0.1 12.0 3.4 0.12 11.8 2.4 1.1 1 0 0 1 1 1 0 Plasmid replication protein UL11 PF11094.3 CAR28681.1 - 0.14 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Membrane-associated tegument protein VHS PF00790.14 CAR28682.1 - 6.2e-47 158.7 0.0 2.5e-46 156.7 0.0 2.0 2 0 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.15 CAR28682.1 - 8e-18 64.8 0.0 1.6e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.9 CAR28682.1 - 3.5e-11 42.9 1.8 1.2e-10 41.2 1.2 2.0 1 0 0 1 1 1 1 GAT domain HSA PF07529.8 CAR28683.1 - 8.2e-17 60.7 0.0 8.2e-17 60.7 0.0 4.5 4 1 1 5 5 5 1 HSA Myb_DNA-bind_6 PF13921.1 CAR28683.1 - 8.6e-10 38.5 0.5 2.9e-09 36.9 0.3 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain BCIP PF13862.1 CAR28684.1 - 9.9e-51 172.0 0.2 1.3e-50 171.5 0.1 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein SET PF00856.23 CAR28685.1 - 0.049 13.9 0.0 0.14 12.4 0.0 1.8 2 0 0 2 2 2 0 SET domain EMP24_GP25L PF01105.19 CAR28686.1 - 7.2e-40 136.6 0.1 8.4e-40 136.4 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD ThiF PF00899.16 CAR28687.1 - 9.4e-43 145.3 0.0 1.5e-42 144.6 0.0 1.3 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 CAR28687.1 - 8.2e-25 86.2 0.6 1.3e-24 85.5 0.4 1.3 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 CAR28687.1 - 1.6e-14 54.2 0.0 2.7e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 CAR28687.1 - 0.0002 21.4 0.0 0.00043 20.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Mto2_bdg PF12808.2 CAR28687.1 - 0.058 13.5 0.5 0.13 12.4 0.3 1.5 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region HALZ PF02183.13 CAR28687.1 - 0.15 11.7 1.7 0.37 10.5 1.2 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper AT_hook PF02178.14 CAR28688.1 - 5.3 7.0 12.5 0.12 12.0 3.9 2.0 2 0 0 2 2 2 0 AT hook motif Cys_Met_Meta_PP PF01053.15 CAR28689.1 - 8.8e-65 218.4 0.0 2.5e-64 216.9 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 CAR28689.1 - 4.5e-05 22.3 0.0 7.2e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 CAR28689.1 - 0.013 14.4 0.0 0.017 14.1 0.0 1.3 1 1 0 1 1 1 0 Aminotransferase class I and II DUF2990 PF11693.3 CAR28689.1 - 0.27 11.1 0.9 46 3.9 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2990) Peptidase_M18 PF02127.10 CAR28690.1 - 1e-173 577.8 0.0 1.2e-173 577.6 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 CAR28690.1 - 9.3e-09 34.4 0.0 1.4e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase CBM_2 PF00553.14 CAR28690.1 - 0.019 15.0 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 Cellulose binding domain Rad60-SLD PF11976.3 CAR28691.1 - 9.6e-23 79.6 2.2 1.1e-21 76.3 2.1 2.2 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Packaging_FI PF14000.1 CAR28691.1 - 1.2 9.3 11.2 0.14 12.3 0.7 2.6 2 0 0 2 2 2 0 DNA packaging protein FI CDC45 PF02724.9 CAR28691.1 - 4.1 5.3 9.9 7.5 4.4 6.8 1.4 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rpb1_5 PF04998.12 CAR28692.1 - 1e-95 320.1 0.1 1.6e-95 319.5 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 CAR28692.1 - 2.9e-81 273.3 0.0 4.9e-81 272.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 CAR28692.1 - 3.6e-69 231.9 0.0 1.2e-68 230.2 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 CAR28692.1 - 2.7e-38 131.1 0.0 7e-38 129.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 CAR28692.1 - 1.5e-30 105.1 0.0 3.4e-30 103.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DSS1_SEM1 PF05160.8 CAR28693.1 - 2.9e-21 75.0 19.9 3.2e-21 74.8 13.8 1.0 1 0 0 1 1 1 1 DSS1/SEM1 family AAA PF00004.24 CAR28694.1 - 4e-41 140.3 0.1 9.2e-41 139.1 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CAR28694.1 - 3e-05 23.7 0.9 0.00015 21.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CAR28694.1 - 5.5e-05 23.1 0.0 0.0002 21.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CAR28694.1 - 0.00015 21.8 0.1 0.011 15.6 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CAR28694.1 - 0.00027 21.0 0.2 0.0072 16.4 0.1 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CAR28694.1 - 0.00056 19.0 0.1 0.0013 17.8 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus PhoH PF02562.11 CAR28694.1 - 0.0065 15.7 0.1 0.027 13.7 0.0 1.9 2 0 0 2 2 2 1 PhoH-like protein AAA_33 PF13671.1 CAR28694.1 - 0.0076 16.1 0.0 0.017 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CAR28694.1 - 0.0083 15.8 0.1 0.025 14.3 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 CAR28694.1 - 0.0088 16.8 0.2 0.029 15.1 0.0 2.0 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CAR28694.1 - 0.0093 15.3 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 CAR28694.1 - 0.013 14.6 0.1 0.034 13.3 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 CAR28694.1 - 0.017 14.0 0.0 0.033 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_11 PF13086.1 CAR28694.1 - 0.018 14.6 0.1 0.28 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CAR28694.1 - 0.019 14.3 0.7 0.15 11.4 0.1 2.2 1 1 1 2 2 2 0 AAA domain BLOC1_2 PF10046.4 CAR28694.1 - 0.026 14.6 0.8 0.09 12.9 0.5 1.9 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 KaiC PF06745.8 CAR28694.1 - 0.039 13.0 0.5 0.14 11.2 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.1 CAR28694.1 - 0.064 12.8 0.6 0.14 11.7 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 CAR28694.1 - 0.066 13.1 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CAR28694.1 - 0.13 12.4 0.0 0.47 10.6 0.0 2.0 2 0 0 2 2 2 0 RNA helicase WD40 PF00400.27 CAR28695.1 - 6.8e-38 127.2 4.1 4.7e-09 35.7 0.0 6.2 6 1 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 CAR28695.1 - 0.0024 17.6 0.2 2.7 7.6 0.0 3.1 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CAR28695.1 - 0.012 13.7 0.1 3.7 5.5 0.0 2.6 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Daxx PF03344.10 CAR28695.1 - 1.4 7.2 11.4 1.9 6.8 7.9 1.1 1 0 0 1 1 1 0 Daxx Family NUC153 PF08159.7 CAR28696.1 - 1.3e-12 47.0 1.8 1.3e-12 47.0 1.2 3.3 3 0 0 3 3 3 1 NUC153 domain BLVR PF06375.6 CAR28696.1 - 0.0049 16.6 13.1 0.0049 16.6 9.1 6.1 3 1 2 6 6 6 1 Bovine leukaemia virus receptor (BLVR) FYVE_2 PF02318.11 CAR28696.1 - 0.77 9.6 9.0 2.5 8.0 6.2 1.9 1 0 0 1 1 1 0 FYVE-type zinc finger TLD PF07534.11 CAR28697.1 - 1.9e-25 89.4 0.0 7e-23 81.1 0.0 2.3 2 0 0 2 2 2 2 TLD RIO1 PF01163.17 CAR28698.1 - 2.1e-70 235.9 0.6 2.1e-70 235.9 0.4 2.0 2 0 0 2 2 2 1 RIO1 family Nop14 PF04147.7 CAR28698.1 - 0.017 13.1 26.2 0.023 12.6 18.1 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.7 CAR28698.1 - 0.083 12.5 26.5 0.13 11.9 18.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein APH PF01636.18 CAR28698.1 - 0.19 11.4 2.1 1.5 8.4 0.2 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family YL1 PF05764.8 CAR28698.1 - 1.2 8.6 32.6 2 7.9 22.6 1.3 1 0 0 1 1 1 0 YL1 nuclear protein DUF2201_N PF13203.1 CAR28698.1 - 2.5 7.1 8.2 3.7 6.6 5.7 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.9 CAR28698.1 - 2.8 5.8 27.3 4.8 5.0 18.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Kei1 PF08552.6 CAR28699.1 - 4.9e-44 150.2 16.9 8.1e-42 143.0 11.7 2.0 1 1 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Integrase_DNA PF02920.10 CAR28699.1 - 0.043 13.2 0.1 0.071 12.5 0.1 1.3 1 0 0 1 1 1 0 DNA binding domain of tn916 integrase Aldo_ket_red PF00248.16 CAR28700.1 - 1.3e-53 181.6 0.0 1.6e-53 181.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family FHA PF00498.21 CAR28701.1 - 0.00018 21.5 0.1 0.00047 20.2 0.0 1.7 1 0 0 1 1 1 1 FHA domain Bac_surface_Ag PF01103.18 CAR28702.1 - 3.6e-23 82.5 5.8 3.6e-23 82.5 4.0 1.9 1 1 1 2 2 2 1 Surface antigen RAI1 PF08652.6 CAR28703.1 - 0.0087 15.8 0.6 0.025 14.3 0.0 2.1 3 0 0 3 3 3 1 RAI1 like PD-(D/E)XK nuclease YCII PF03795.9 CAR28704.1 - 0.00021 21.4 0.0 0.00024 21.2 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Profilin PF00235.14 CAR28705.1 - 2.3e-39 134.2 0.0 2.6e-39 134.0 0.0 1.0 1 0 0 1 1 1 1 Profilin Leo1 PF04004.8 CAR28706.1 - 6.6e-45 152.8 0.0 6.6e-45 152.8 0.0 2.7 2 0 0 2 2 2 1 Leo1-like protein Glyco_hydro_18 PF00704.23 CAR28707.1 - 5.8e-78 262.7 1.2 3.6e-77 260.1 0.8 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 GPP34 PF05719.6 CAR28708.1 - 2.2e-61 207.5 0.0 2.7e-61 207.2 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Asp PF00026.18 CAR28709.1 - 2.4e-69 234.0 8.5 1.6e-68 231.2 5.9 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CAR28709.1 - 1.2e-05 25.3 6.3 0.0098 15.8 0.0 2.8 3 0 0 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CAR28709.1 - 0.00085 19.7 1.2 12 6.5 0.0 4.1 4 0 0 4 4 4 2 Aspartyl protease RVP PF00077.15 CAR28709.1 - 0.0027 17.5 0.1 1.8 8.5 0.0 2.9 3 0 0 3 3 3 2 Retroviral aspartyl protease TAXi_C PF14541.1 CAR28709.1 - 0.023 14.2 0.0 0.53 9.8 0.0 2.3 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Asp PF00026.18 CAR28710.1 - 1.8e-71 241.0 4.1 3.7e-71 239.9 2.8 1.5 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CAR28710.1 - 1.9e-09 37.6 2.1 1.9e-09 37.6 1.5 3.0 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CAR28710.1 - 0.00014 21.4 0.0 0.0007 19.1 0.0 2.0 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 CAR28710.1 - 0.013 15.9 1.8 6.7 7.2 0.0 3.7 2 1 1 3 3 3 0 Aspartyl protease gag-asp_proteas PF13975.1 CAR28710.1 - 0.052 13.3 0.1 3.1 7.6 0.1 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Sec3_C PF09763.4 CAR28710.1 - 1.7 6.6 4.4 2.2 6.2 3.0 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 DUF4614 PF15391.1 CAR28710.1 - 3.9 7.2 13.1 9.1 6.0 9.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Asp PF00026.18 CAR28711.1 - 5.2e-74 249.3 2.9 9.2e-74 248.5 2.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CAR28711.1 - 1.1e-07 31.9 0.0 1.4e-06 28.3 0.0 2.6 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CAR28711.1 - 0.00063 20.1 0.4 9.2 6.8 0.0 3.7 3 0 0 3 3 3 2 Aspartyl protease Inhibitor_I36 PF03995.8 CAR28711.1 - 0.0045 17.3 1.1 0.012 15.9 0.7 1.7 1 0 0 1 1 1 1 Peptidase inhibitor family I36 Asp PF00026.18 CAR28712.1 - 7.6e-67 225.7 1.7 2.1e-66 224.3 0.9 1.8 2 1 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CAR28712.1 - 1.4e-07 31.5 0.0 4e-06 26.8 0.0 3.3 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CAR28712.1 - 0.00014 22.3 0.1 4.1 7.9 0.0 4.2 3 1 0 4 4 4 2 Aspartyl protease TAXi_C PF14541.1 CAR28712.1 - 0.00088 18.8 0.1 0.024 14.1 0.0 2.3 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp PF00026.18 CAR28713.1 - 8.4e-76 255.2 3.1 1.2e-75 254.7 2.2 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CAR28713.1 - 4.3e-11 43.0 2.0 9.1e-11 41.9 0.3 2.1 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CAR28713.1 - 0.00086 19.7 0.4 15 6.1 0.0 3.8 3 0 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 CAR28713.1 - 0.0044 16.5 0.7 0.13 11.7 0.2 2.6 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Cullin PF00888.17 CAR28714.1 - 2.3e-27 95.7 0.0 4.6e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 Cullin family APC2 PF08672.6 CAR28714.1 - 9.8e-21 73.7 0.1 1.1e-18 67.2 0.1 2.9 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 EAP30 PF04157.11 CAR28714.1 - 0.021 14.0 0.0 0.046 12.8 0.0 1.6 1 0 0 1 1 1 0 EAP30/Vps36 family Cullin_binding PF03556.10 CAR28715.1 - 1.7e-28 99.0 5.4 3e-28 98.3 3.8 1.4 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 CAR28715.1 - 8e-14 50.8 0.6 1.5e-13 50.0 0.4 1.5 1 0 0 1 1 1 1 UBA-like domain TFIID_20kDa PF03847.8 CAR28716.1 - 4.6e-32 110.1 1.9 5.4e-32 109.8 0.2 2.0 2 0 0 2 2 2 1 Transcription initiation factor TFIID subunit A Histone PF00125.19 CAR28716.1 - 0.015 15.4 0.0 0.066 13.3 0.0 2.2 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 WD40 PF00400.27 CAR28717.1 - 1.6e-71 233.7 28.1 7e-08 32.0 0.0 11.7 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp12 PF04003.7 CAR28717.1 - 3.5e-24 84.8 0.7 6.1e-24 84.0 0.5 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 CAR28717.1 - 7.4e-05 21.0 12.2 0.022 12.9 0.0 6.1 2 2 1 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CAR28717.1 - 0.00048 18.9 15.2 1.8 7.2 0.1 6.3 1 1 2 5 5 5 4 Nup133 N terminal like Hira PF07569.6 CAR28717.1 - 0.026 13.7 4.5 12 5.0 0.1 5.0 5 1 0 5 5 5 0 TUP1-like enhancer of split CBM_2 PF00553.14 CAR28717.1 - 0.086 12.9 0.0 0.53 10.3 0.0 2.4 1 0 0 1 1 1 0 Cellulose binding domain zf-C2H2 PF00096.21 CAR28718.1 - 1.1e-08 34.9 21.3 0.0013 18.9 1.5 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CAR28718.1 - 6.7e-05 22.9 12.5 0.016 15.5 0.9 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CAR28718.1 - 0.00091 19.4 0.1 0.00091 19.4 0.0 4.9 5 0 0 5 5 5 1 Zinc-finger double domain Bunya_G2 PF03563.8 CAR28718.1 - 0.14 10.9 1.3 0.23 10.3 0.9 1.2 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 zf-C2H2_jaz PF12171.3 CAR28718.1 - 1.1 9.4 12.1 7.3 6.8 0.4 3.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CAR28718.1 - 1.3 9.0 8.0 0.58 10.1 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger HVSL PF09749.4 CAR28719.1 - 3.5e-25 88.4 0.4 4.4e-25 88.1 0.3 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein DUF881 PF05949.7 CAR28719.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF881) Choline_kinase PF01633.15 CAR28720.1 - 5.2e-67 225.4 0.0 7.4e-67 224.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 CAR28720.1 - 2.6e-12 46.0 0.0 5.1e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.18 CAR28720.1 - 2.3e-08 34.0 0.0 0.0041 16.9 0.0 2.5 2 1 0 2 2 2 2 Phosphotransferase enzyme family 2-oxoacid_dh PF00198.18 CAR28721.1 - 9.4e-79 263.9 0.0 1.2e-78 263.5 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CAR28721.1 - 3.5e-17 61.7 1.2 6.1e-17 61.0 0.9 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme GCV_H PF01597.14 CAR28721.1 - 0.00042 19.9 0.3 0.00096 18.8 0.2 1.7 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD_3 PF13437.1 CAR28721.1 - 0.00052 20.3 0.6 0.014 15.7 0.1 2.6 1 1 1 2 2 2 1 HlyD family secretion protein HlyD_2 PF12700.2 CAR28721.1 - 0.0018 17.4 1.0 0.031 13.4 0.1 2.2 1 1 1 2 2 2 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 CAR28721.1 - 0.0021 17.6 0.4 0.0071 15.9 0.1 1.9 1 1 1 2 2 2 1 Biotin-lipoyl like RnfC_N PF13375.1 CAR28721.1 - 0.0057 16.3 0.3 0.065 12.9 0.0 2.3 1 1 1 2 2 2 1 RnfC Barrel sandwich hybrid domain Slx4 PF09494.5 CAR28722.1 - 2.9e-15 55.7 0.0 5.7e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Slx4 endonuclease Mcp5_PH PF12814.2 CAR28723.1 - 2.4e-37 127.5 0.3 9.7e-37 125.6 0.0 2.3 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology DUF3360 PF11840.3 CAR28723.1 - 6.7 4.9 1.3 11 4.2 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3360) zf-CCCH PF00642.19 CAR28724.1 - 6.3e-18 64.0 17.8 5.1e-10 38.7 2.3 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CAR28724.1 - 0.024 14.6 12.6 0.042 13.8 0.8 2.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Arginase PF00491.16 CAR28726.1 - 4e-72 242.8 0.0 4.7e-72 242.6 0.0 1.0 1 0 0 1 1 1 1 Arginase family PEX11 PF05648.9 CAR28727.1 - 1.3e-06 27.8 2.4 3.2e-06 26.5 1.7 1.6 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) 2-Hacid_dh_C PF02826.14 CAR28728.1 - 5.8e-35 120.0 0.0 8.7e-35 119.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 CAR28728.1 - 0.00022 21.0 0.0 0.0004 20.2 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TFIIA PF03153.8 CAR28729.1 - 4.1e-57 194.7 24.1 2.2e-34 119.9 10.5 2.1 1 1 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Kinetocho_Slk19 PF12709.2 CAR28730.1 - 2.5e-31 107.6 13.1 2.5e-31 107.6 9.1 8.0 3 2 3 7 7 7 2 Central kinetochore-associated AAA_13 PF13166.1 CAR28730.1 - 0.00014 20.5 28.3 0.00014 20.5 19.6 3.2 1 1 2 3 3 3 3 AAA domain TPR_MLP1_2 PF07926.7 CAR28730.1 - 0.00035 20.3 44.8 0.0013 18.5 11.7 5.8 3 2 2 5 5 4 3 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 CAR28730.1 - 0.0015 17.7 24.6 0.0079 15.4 0.7 4.5 1 1 3 4 4 4 3 Reovirus sigma C capsid protein Filament PF00038.16 CAR28730.1 - 0.0051 16.3 81.5 0.39 10.1 13.4 5.1 1 1 1 3 3 3 3 Intermediate filament protein rve_3 PF13683.1 CAR28730.1 - 0.019 14.4 5.0 1.6 8.3 0.2 4.4 4 0 0 4 4 4 0 Integrase core domain Myosin_tail_1 PF01576.14 CAR28730.1 - 0.077 10.7 84.5 0.15 9.7 33.7 2.7 1 1 1 2 2 2 0 Myosin tail NPV_P10 PF05531.7 CAR28730.1 - 0.12 12.6 29.9 1.8 8.8 0.0 7.3 5 2 1 6 6 6 0 Nucleopolyhedrovirus P10 protein DUF869 PF05911.6 CAR28730.1 - 0.59 8.2 74.5 1.5 6.9 23.3 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) IncA PF04156.9 CAR28730.1 - 0.69 9.4 92.4 1 8.8 1.2 6.2 2 2 3 6 6 6 0 IncA protein WEMBL PF05701.6 CAR28730.1 - 1.1 7.6 76.9 0.0052 15.2 6.2 3.2 1 1 1 3 3 3 0 Weak chloroplast movement under blue light AAA_27 PF13514.1 CAR28730.1 - 7.5 4.0 60.5 8.9 3.8 6.1 2.9 1 1 1 2 2 2 0 AAA domain RhoGAP PF00620.22 CAR28731.1 - 3.3e-37 127.4 0.2 8.8e-37 126.0 0.1 1.7 1 0 0 1 1 1 1 RhoGAP domain PX PF00787.19 CAR28731.1 - 3.3e-07 30.0 1.5 8.1e-07 28.8 1.0 1.7 1 0 0 1 1 1 1 PX domain PH PF00169.24 CAR28731.1 - 3.2e-05 24.0 0.0 8.1e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF1708 PF08101.6 CAR28731.1 - 0.00023 20.1 0.0 0.0005 19.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) DivIC PF04977.10 CAR28731.1 - 0.2 11.1 1.4 0.46 10.0 1.0 1.5 1 0 0 1 1 1 0 Septum formation initiator Radical_SAM PF04055.16 CAR28732.1 - 7.7e-13 48.9 0.0 1.3e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Ivy PF08816.6 CAR28732.1 - 0.039 13.9 0.0 0.09 12.7 0.0 1.5 1 0 0 1 1 1 0 Inhibitor of vertebrate lysozyme (Ivy) Hist_deacetyl PF00850.14 CAR28733.1 - 6.3e-64 216.2 0.1 8.7e-64 215.7 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain DUF4258 PF14076.1 CAR28733.1 - 0.069 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4258) Peptidase_C14 PF00656.17 CAR28734.1 - 2.4e-69 233.7 0.0 3.2e-69 233.3 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Baculo_PEP_C PF04513.7 CAR28735.1 - 0.00047 19.9 26.3 0.91 9.3 2.4 5.0 2 1 3 5 5 5 4 Baculovirus polyhedron envelope protein, PEP, C terminus DUF342 PF03961.8 CAR28735.1 - 0.002 16.6 13.6 0.002 16.6 9.4 3.9 2 1 2 4 4 4 3 Protein of unknown function (DUF342) NUDIX PF00293.23 CAR28736.1 - 2.9e-26 91.7 0.0 4e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain SpoU_methylase PF00588.14 CAR28737.1 - 2.6e-26 92.2 0.0 1e-25 90.2 0.0 1.9 2 0 0 2 2 2 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 CAR28737.1 - 2e-15 56.6 0.0 4.1e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding IGPD PF00475.13 CAR28738.1 - 5.2e-60 201.5 0.3 7.2e-60 201.0 0.2 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Mit_ribos_Mrp51 PF11709.3 CAR28739.1 - 7.4e-93 311.1 0.3 8.8e-93 310.9 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit DEAD PF00270.24 CAR28740.1 - 6.2e-46 155.9 0.0 2.9e-44 150.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR28740.1 - 1.3e-27 95.4 0.1 2.8e-27 94.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAR28740.1 - 0.00011 22.0 0.0 0.00044 20.1 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 CAR28740.1 - 0.066 12.2 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Ribonuc_red_lgC PF02867.10 CAR28741.1 - 1.8e-204 680.2 0.0 2.2e-204 679.9 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 CAR28741.1 - 2.6e-24 84.8 0.0 5.6e-24 83.7 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain NRDD PF13597.1 CAR28741.1 - 0.0058 14.7 0.0 0.0087 14.1 0.0 1.2 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase APG6 PF04111.7 CAR28742.1 - 3.1e-108 361.5 9.5 3.9e-108 361.2 6.6 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 DUF972 PF06156.8 CAR28742.1 - 0.014 15.7 7.2 0.041 14.2 5.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Toxin_60 PF15607.1 CAR28742.1 - 0.37 10.8 2.3 1.2 9.1 0.0 2.5 3 0 0 3 3 3 0 Putative toxin 60 AATF-Che1 PF13339.1 CAR28742.1 - 0.52 10.4 10.9 1.8 8.7 7.6 2.0 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor V_ATPase_I PF01496.14 CAR28742.1 - 1.8 6.2 7.0 2.7 5.7 4.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MMR_HSR1 PF01926.18 CAR28743.1 - 8.5e-08 32.1 0.3 9.3e-07 28.8 0.1 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 CAR28743.1 - 0.0011 18.1 0.0 0.0023 17.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CAR28743.1 - 0.017 15.2 0.0 0.058 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 CAR28743.1 - 0.049 13.3 0.0 0.2 11.3 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 CAR28743.1 - 0.05 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Dynamin_N PF00350.18 CAR28743.1 - 0.05 13.4 0.1 0.53 10.0 0.0 2.2 1 1 1 2 2 2 0 Dynamin family AAA_29 PF13555.1 CAR28743.1 - 0.089 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.13 CAR28743.1 - 0.091 12.0 0.0 0.29 10.4 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B Noc2 PF03715.8 CAR28744.1 - 1.6e-127 424.4 5.6 1.6e-127 424.4 3.9 2.5 3 0 0 3 3 3 1 Noc2p family Mei5 PF10376.4 CAR28745.1 - 4.6e-36 124.4 20.4 5.4e-36 124.1 14.1 1.1 1 0 0 1 1 1 1 Double-strand recombination repair protein Pup PF05639.6 CAR28745.1 - 0.12 12.9 1.1 0.12 12.9 0.8 2.2 2 0 0 2 2 2 0 Pup-like protein RNA_pol_Rpb2_6 PF00562.23 CAR28746.1 - 7.6e-119 396.8 0.1 7.6e-119 396.8 0.1 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CAR28746.1 - 1.7e-59 200.1 1.3 2.9e-59 199.4 0.9 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 CAR28746.1 - 2.5e-41 141.2 4.1 7.7e-41 139.5 1.6 2.5 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 CAR28746.1 - 4.5e-30 103.7 0.1 1.4e-29 102.1 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 CAR28746.1 - 4.6e-27 93.6 0.2 1.8e-26 91.7 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 CAR28746.1 - 7.5e-19 67.2 0.0 1.8e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 CAR28746.1 - 4.2e-12 45.8 0.4 1.3e-11 44.2 0.3 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Baculo_Y142 PF04913.7 CAR28746.1 - 0.00067 18.1 0.2 0.0014 17.1 0.1 1.4 1 0 0 1 1 1 1 Baculovirus Y142 protein DUF2824 PF11039.3 CAR28746.1 - 0.1 12.3 0.5 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2824) Tfb2 PF03849.9 CAR28747.1 - 8.7e-154 511.5 2.4 1.2e-153 511.1 1.7 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 CAR28747.1 - 1.3e-05 24.9 0.0 3.9e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PAS PF00989.19 CAR28747.1 - 0.059 13.1 0.0 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 PAS fold HTH_45 PF14947.1 CAR28747.1 - 0.13 12.0 0.9 0.33 10.7 0.0 2.2 3 0 0 3 3 3 0 Winged helix-turn-helix Coatomer_WDAD PF04053.9 CAR28748.1 - 2.8e-133 444.9 1.3 4.5e-133 444.2 0.9 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 CAR28748.1 - 1.4e-68 231.3 0.0 2.2e-68 230.7 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 CAR28748.1 - 1.9e-55 182.8 12.3 1.2e-09 37.6 0.0 7.8 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 CAR28748.1 - 8.6e-08 30.7 3.7 0.11 10.6 0.0 3.6 2 1 2 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.6 CAR28748.1 - 1.8e-05 24.5 0.4 0.31 10.7 0.0 3.7 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A ENTH PF01417.15 CAR28748.1 - 0.0076 16.1 0.1 0.022 14.6 0.1 1.7 1 0 0 1 1 1 1 ENTH domain LisH PF08513.6 CAR28748.1 - 0.03 14.0 0.1 0.2 11.4 0.0 2.3 2 0 0 2 2 2 0 LisH TPR_11 PF13414.1 CAR28748.1 - 0.095 12.3 0.0 0.31 10.7 0.0 1.9 1 0 0 1 1 1 0 TPR repeat TPR_1 PF00515.23 CAR28748.1 - 0.13 11.9 0.1 0.56 9.9 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat Tubulin PF00091.20 CAR28750.1 - 5.4e-70 235.5 0.0 8.3e-70 234.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CAR28750.1 - 3e-23 82.2 0.0 6.4e-23 81.1 0.0 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CAR28750.1 - 4.6e-08 33.1 0.0 1e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain DUF2013 PF09431.5 CAR28751.1 - 1.2e-41 141.7 14.5 1.2e-41 141.7 10.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) TBPIP PF07106.8 CAR28752.1 - 0.057 12.9 2.6 0.2 11.2 0.0 2.2 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) MIT PF04212.13 CAR28752.1 - 0.064 13.1 0.6 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Spectrin PF00435.16 CAR28752.1 - 0.29 11.4 5.4 0.8 10.0 1.2 2.7 2 1 0 2 2 2 0 Spectrin repeat PCI PF01399.22 CAR28753.1 - 1.2e-18 67.3 0.7 4.2e-18 65.5 0.0 2.3 2 0 0 2 2 2 1 PCI domain OEP PF02321.13 CAR28753.1 - 0.03 13.9 3.2 0.077 12.5 2.2 1.7 1 0 0 1 1 1 0 Outer membrane efflux protein Nop14 PF04147.7 CAR28754.1 - 1.5e-223 744.3 73.8 2.7e-127 425.9 6.2 2.0 1 1 1 2 2 2 2 Nop14-like family APG9 PF04109.11 CAR28755.1 - 5e-164 545.5 4.2 6.9e-164 545.1 2.9 1.2 1 0 0 1 1 1 1 Autophagy protein Apg9 RNA_pol_Rpc4 PF05132.9 CAR28756.1 - 5.4e-27 94.3 0.0 5.4e-27 94.3 0.0 3.3 4 0 0 4 4 4 1 RNA polymerase III RPC4 DUF3713 PF12506.3 CAR28756.1 - 0.65 10.0 6.1 2.4 8.2 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3713) NEMO PF11577.3 CAR28756.1 - 2.7 7.8 7.4 0.15 11.8 0.8 2.1 3 0 0 3 3 3 0 NF-kappa-B essential modulator NEMO Sas10 PF09368.5 CAR28757.1 - 9.2e-30 102.6 8.0 9.2e-30 102.6 5.5 2.2 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 CAR28757.1 - 4.9e-10 39.4 1.0 2.6e-09 37.1 0.7 2.3 1 0 0 1 1 1 1 Sas10/Utp3/C1D family MutS_V PF00488.16 CAR28758.1 - 2.6e-55 187.3 0.0 4.8e-55 186.5 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CAR28758.1 - 3.1e-27 95.6 1.4 3.1e-27 95.6 0.9 2.0 3 0 0 3 3 3 1 MutS domain III Cyclin_N PF00134.18 CAR28759.1 - 1.2e-44 150.8 0.2 2.7e-44 149.7 0.2 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CAR28759.1 - 2.1e-28 98.6 0.0 2.1e-28 98.6 0.0 2.1 3 0 0 3 3 3 1 Cyclin, C-terminal domain Prothymosin PF03247.9 CAR28759.1 - 0.012 15.7 19.2 0.025 14.7 13.3 1.5 1 0 0 1 1 1 0 Prothymosin/parathymosin family DUF3245 PF11595.3 CAR28759.1 - 0.046 14.0 7.2 0.11 12.7 5.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) RXT2_N PF08595.6 CAR28759.1 - 0.16 11.7 8.3 0.48 10.2 5.7 1.8 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.7 CAR28759.1 - 0.21 10.7 10.7 0.44 9.7 7.4 1.4 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 CAR28759.1 - 0.27 10.7 17.4 0.49 9.9 12.0 1.4 1 0 0 1 1 1 0 Nucleoplasmin TFIIA PF03153.8 CAR28759.1 - 1 9.2 21.0 1.4 8.7 14.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CENP-B_dimeris PF09026.5 CAR28759.1 - 1.2 9.3 15.9 3.2 8.0 11.1 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RNA_pol_3_Rpc31 PF11705.3 CAR28759.1 - 3.1 7.6 19.8 7.7 6.3 13.7 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 WD40 PF00400.27 CAR28760.1 - 1.9e-11 43.3 9.4 0.00034 20.3 0.1 5.3 5 1 0 5 5 5 3 WD domain, G-beta repeat DUF3312 PF11768.3 CAR28760.1 - 0.094 10.9 0.0 4.5 5.3 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3312) Pkinase PF00069.20 CAR28762.1 - 4.7e-65 219.3 0.0 6.8e-65 218.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR28762.1 - 1.4e-38 132.4 0.0 2.1e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR28762.1 - 4.2e-05 22.6 0.0 0.00011 21.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CAR28762.1 - 0.1 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DEAD PF00270.24 CAR28763.1 - 1.4e-41 141.8 0.1 2.3e-41 141.1 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR28763.1 - 2.3e-25 88.2 0.2 4.5e-25 87.3 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PAT1 PF09770.4 CAR28763.1 - 7.6 4.6 18.5 12 4.0 12.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PNP_UDP_1 PF01048.15 CAR28764.1 - 2.7e-43 147.6 0.0 4.5e-43 146.8 0.0 1.4 1 1 0 1 1 1 1 Phosphorylase superfamily WD40 PF00400.27 CAR28765.1 - 1.2e-42 142.2 20.1 2.8e-10 39.6 0.5 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 CAR28765.1 - 0.0041 16.8 7.8 0.15 11.7 1.0 3.5 1 1 2 3 3 3 2 Transcription factor IIIC subunit delta N-term YmzC PF14157.1 CAR28765.1 - 0.025 14.4 0.0 7.8 6.4 0.0 3.4 4 0 0 4 4 4 0 YmzC-like protein Sel1 PF08238.7 CAR28766.1 - 4e-22 78.1 8.8 2.1e-05 24.9 0.1 8.7 9 0 0 9 9 9 4 Sel1 repeat TPR_19 PF14559.1 CAR28766.1 - 0.0016 18.7 0.9 1.4 9.3 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CAR28766.1 - 0.037 13.9 3.9 2.4 8.1 0.1 4.8 4 2 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 CAR28766.1 - 0.043 13.4 13.7 0.063 12.9 0.2 4.3 5 1 1 6 6 6 0 TPR repeat TPR_2 PF07719.12 CAR28766.1 - 0.17 11.8 7.4 4.2 7.5 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 CAR28766.1 - 0.33 10.8 10.4 8.2 6.4 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 CAR28766.1 - 1.1 9.6 4.9 5.8 7.3 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 CAR28766.1 - 5.3 6.8 16.2 1.3 8.7 0.0 5.2 7 0 0 7 7 7 0 Tetratricopeptide repeat CENP-X PF09415.5 CAR28767.1 - 3.1e-25 87.7 0.1 3.9e-25 87.4 0.1 1.1 1 0 0 1 1 1 1 CENP-S associating Centromere protein X CBFD_NFYB_HMF PF00808.18 CAR28767.1 - 0.052 13.6 0.1 0.087 12.8 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ENTH PF01417.15 CAR28768.1 - 1.1e-40 138.3 0.0 2.4e-40 137.2 0.0 1.6 1 0 0 1 1 1 1 ENTH domain DNA_ligase_A_M PF01068.16 CAR28769.1 - 3.4e-58 196.3 0.0 6.1e-58 195.5 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 CAR28769.1 - 6.3e-56 188.9 0.2 6.4e-55 185.7 0.0 2.1 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 CAR28769.1 - 3e-25 88.4 0.0 8.4e-25 87.0 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 CAR28769.1 - 0.03 13.9 0.4 8.2 6.1 0.0 2.5 2 0 0 2 2 2 0 DNA ligase OB-like domain Heme_oxygenase PF01126.15 CAR28770.1 - 6e-13 48.8 1.2 2.9e-12 46.5 0.8 2.2 1 1 0 1 1 1 1 Heme oxygenase Erf4 PF10256.4 CAR28770.1 - 0.09 12.6 0.1 1.3 8.8 0.0 2.4 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family PT-VENN PF04829.8 CAR28770.1 - 0.17 11.4 0.3 0.33 10.5 0.2 1.5 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif zf-Mss51 PF13824.1 CAR28771.1 - 4.5e-19 68.0 0.7 9.3e-19 67.0 0.5 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 YL1_C PF08265.6 CAR28771.1 - 0.0018 17.7 0.0 0.0049 16.3 0.0 1.7 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain BOP1NT PF08145.7 CAR28771.1 - 0.048 13.4 0.2 0.076 12.7 0.1 1.2 1 0 0 1 1 1 0 BOP1NT (NUC169) domain NOT2_3_5 PF04153.13 CAR28772.1 - 9.7e-35 119.3 1.9 1.2e-34 119.1 1.3 1.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family AAA_18 PF13238.1 CAR28773.1 - 5.2e-28 97.9 0.6 7.3e-28 97.4 0.1 1.5 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.1 CAR28773.1 - 2.9e-15 57.1 0.1 4.2e-15 56.6 0.1 1.5 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 CAR28773.1 - 2.6e-05 23.6 0.1 0.062 12.6 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase KTI12 PF08433.5 CAR28773.1 - 8e-05 21.9 0.0 0.00028 20.1 0.0 1.8 2 0 0 2 2 2 1 Chromatin associated protein KTI12 RNA_helicase PF00910.17 CAR28773.1 - 0.00011 22.2 0.2 0.0007 19.7 0.0 2.0 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.1 CAR28773.1 - 0.00041 20.2 0.0 0.035 13.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CAR28773.1 - 0.00087 19.0 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 CAR28773.1 - 0.0011 18.9 0.0 0.0022 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CAR28773.1 - 0.0012 17.9 0.0 0.0048 16.0 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.1 CAR28773.1 - 0.002 18.1 0.0 0.0056 16.6 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 CAR28773.1 - 0.002 17.6 1.4 0.0048 16.4 0.2 1.9 1 1 1 2 2 2 1 FtsK/SpoIIIE family AAA_29 PF13555.1 CAR28773.1 - 0.0031 17.0 0.0 0.0061 16.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 CAR28773.1 - 0.0044 16.4 0.2 0.011 15.2 0.1 1.6 1 1 1 2 2 2 1 AAA-like domain ADK PF00406.17 CAR28773.1 - 0.0058 16.5 0.1 2.4 8.0 0.0 2.3 2 0 0 2 2 2 1 Adenylate kinase AAA_14 PF13173.1 CAR28773.1 - 0.0077 16.1 0.1 0.017 14.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CAR28773.1 - 0.015 15.4 0.0 0.031 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CAR28773.1 - 0.02 14.6 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain T2SE PF00437.15 CAR28773.1 - 0.03 13.2 0.0 0.054 12.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NTPase_1 PF03266.10 CAR28773.1 - 0.032 13.9 0.0 0.08 12.6 0.0 1.7 1 0 0 1 1 1 0 NTPase ABC_tran PF00005.22 CAR28773.1 - 0.048 13.9 2.7 0.61 10.3 1.9 2.1 1 1 0 1 1 1 0 ABC transporter ArgK PF03308.11 CAR28773.1 - 0.048 12.4 0.0 0.11 11.2 0.0 1.5 2 0 0 2 2 2 0 ArgK protein KAP_NTPase PF07693.9 CAR28773.1 - 0.061 12.3 0.0 0.12 11.3 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain APS_kinase PF01583.15 CAR28773.1 - 0.068 12.8 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF87 PF01935.12 CAR28773.1 - 0.068 12.9 0.4 0.18 11.5 0.3 2.1 1 1 0 1 1 1 0 Domain of unknown function DUF87 FANCI_S1 PF14675.1 CAR28773.1 - 0.078 12.3 0.1 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 FANCI solenoid 1 Mg_chelatase PF01078.16 CAR28773.1 - 0.084 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 CAR28773.1 - 0.09 12.8 0.0 0.29 11.1 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain MobB PF03205.9 CAR28773.1 - 0.11 12.2 0.0 0.26 10.9 0.0 1.7 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 CAR28773.1 - 0.14 12.3 0.0 0.36 11.0 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) zf-RanBP PF00641.13 CAR28774.1 - 4.5e-22 76.8 9.6 7.5e-11 40.9 0.4 2.6 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 CAR28774.1 - 2.9e-08 33.2 0.0 0.00084 18.9 0.0 2.6 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR28774.1 - 0.00019 21.3 0.0 0.0058 16.5 0.0 3.0 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DZR PF12773.2 CAR28774.1 - 0.014 15.2 7.8 0.91 9.3 1.1 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-MIZ PF02891.15 CAR28774.1 - 0.23 11.0 3.1 7.3 6.1 0.1 2.8 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger GCC2_GCC3 PF07699.8 CAR28774.1 - 0.65 9.6 7.7 1.1 8.8 0.2 2.5 2 0 0 2 2 2 0 GCC2 and GCC3 ADH_N PF08240.7 CAR28775.1 - 2.2e-28 98.1 3.0 2.2e-28 98.1 2.1 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CAR28775.1 - 7.5e-22 77.2 0.5 1.5e-21 76.3 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CAR28775.1 - 0.0023 17.0 0.2 0.0038 16.3 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 CAR28775.1 - 0.0049 16.2 0.1 0.0085 15.4 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 CAR28775.1 - 0.0088 16.0 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 CAR28775.1 - 0.028 14.0 2.0 0.051 13.1 1.4 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 3HCDH_N PF02737.13 CAR28775.1 - 0.045 13.4 0.1 0.082 12.5 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 CAR28775.1 - 0.055 13.2 1.2 0.5 10.2 0.5 2.2 1 1 1 2 2 2 0 ThiF family COQ9 PF08511.6 CAR28776.1 - 1.8e-21 75.4 0.2 3.2e-21 74.6 0.1 1.4 1 0 0 1 1 1 1 COQ9 DUF2199 PF09965.4 CAR28776.1 - 0.089 12.6 0.0 0.53 10.1 0.0 2.1 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2199) Prefoldin_2 PF01920.15 CAR28777.1 - 4.8e-24 84.1 8.2 5.6e-24 83.9 5.7 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF1732 PF08340.6 CAR28777.1 - 0.026 14.3 1.7 0.05 13.4 0.9 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1732) DUF4201 PF13870.1 CAR28777.1 - 0.036 13.4 4.2 0.2 11.0 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF1192 PF06698.6 CAR28777.1 - 0.056 13.2 3.5 0.077 12.8 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Spc24 PF08286.6 CAR28777.1 - 0.057 13.1 7.8 0.4 10.3 0.4 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Guanylin PF02058.10 CAR28777.1 - 0.11 12.5 0.1 0.17 11.9 0.1 1.4 1 1 0 1 1 1 0 Guanylin precursor DivIC PF04977.10 CAR28777.1 - 0.12 11.8 9.5 0.17 11.3 0.5 2.5 2 1 0 2 2 2 0 Septum formation initiator Atg14 PF10186.4 CAR28777.1 - 0.16 10.8 3.2 0.19 10.6 2.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 YgaB PF14182.1 CAR28777.1 - 0.21 11.8 5.2 0.43 10.8 0.5 2.2 2 0 0 2 2 2 0 YgaB-like protein CENP-F_leu_zip PF10473.4 CAR28777.1 - 0.42 10.4 8.0 0.76 9.6 0.6 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3166 PF11365.3 CAR28777.1 - 0.53 10.7 5.2 1.1 9.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) Snapin_Pallidin PF14712.1 CAR28777.1 - 0.64 10.3 3.6 3.1 8.1 0.1 2.3 2 1 0 2 2 2 0 Snapin/Pallidin FlxA PF14282.1 CAR28777.1 - 6.5 6.7 8.1 2 8.4 0.4 2.3 1 1 0 2 2 2 0 FlxA-like protein DUF3847 PF12958.2 CAR28777.1 - 7 6.4 8.2 9.3 6.0 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) POC1 PF10450.4 CAR28778.1 - 2.6e-88 295.3 0.0 2.9e-88 295.1 0.0 1.0 1 0 0 1 1 1 1 POC1 chaperone Nop PF01798.13 CAR28779.1 - 3.3e-60 201.7 0.1 7.4e-60 200.6 0.0 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 CAR28779.1 - 3.8e-27 93.8 0.3 1e-26 92.4 0.1 1.8 2 0 0 2 2 2 1 NOSIC (NUC001) domain NOP5NT PF08156.8 CAR28779.1 - 5.1e-24 84.2 0.4 5.1e-24 84.2 0.3 2.8 2 1 0 2 2 2 1 NOP5NT (NUC127) domain RNase_H2-Ydr279 PF09468.5 CAR28779.1 - 0.0014 17.8 18.4 0.0014 17.8 12.8 1.9 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) GAGA_bind PF06217.7 CAR28779.1 - 0.22 11.4 24.1 0.36 10.7 16.7 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.7 CAR28779.1 - 0.25 11.2 32.2 0.39 10.5 22.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.9 CAR28779.1 - 1.4 6.8 28.5 1.8 6.4 19.7 1.1 1 0 0 1 1 1 0 CDC45-like protein NARP1 PF12569.3 CAR28779.1 - 3.2 6.4 39.6 5.6 5.6 27.4 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 AAA_23 PF13476.1 CAR28779.1 - 5.2 7.3 32.4 4.1 7.6 18.0 2.7 2 1 0 2 2 2 0 AAA domain MIP-T3 PF10243.4 CAR28779.1 - 7.2 4.9 54.0 10 4.4 37.4 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 TFR_dimer PF04253.10 CAR28780.1 - 4.6e-35 119.9 0.2 9.3e-35 118.9 0.1 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 CAR28780.1 - 0.0011 18.7 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PIGA PF08288.7 CAR28781.1 - 8e-41 138.3 2.0 2.7e-40 136.6 1.4 2.0 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 CAR28781.1 - 5.3e-33 113.8 0.0 8.4e-33 113.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 CAR28781.1 - 9.4e-22 77.5 0.4 1.8e-21 76.6 0.3 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 CAR28781.1 - 6.2e-16 58.7 0.0 2e-15 57.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CAR28781.1 - 2.1e-15 57.2 0.0 3.2e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 CAR28781.1 - 2.2e-06 27.5 0.3 4.4e-06 26.5 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 CAR28781.1 - 0.0012 19.0 0.0 0.0025 18.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 ER PF01133.12 CAR28781.1 - 0.057 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Enhancer of rudimentary CAP_GLY PF01302.20 CAR28782.1 - 3.6e-21 74.6 1.0 5.7e-21 73.9 0.7 1.3 1 0 0 1 1 1 1 CAP-Gly domain Shugoshin_N PF07558.6 CAR28782.1 - 0.0092 15.6 10.7 0.043 13.5 0.6 4.8 4 0 0 4 4 4 1 Shugoshin N-terminal coiled-coil region DUF972 PF06156.8 CAR28782.1 - 0.037 14.3 0.8 0.037 14.3 0.6 5.6 2 2 5 7 7 7 0 Protein of unknown function (DUF972) Opi1 PF08618.5 CAR28782.1 - 2.2 7.1 6.3 0.21 10.4 0.8 1.9 2 0 0 2 2 2 0 Transcription factor Opi1 HALZ PF02183.13 CAR28782.1 - 2.3 7.9 30.0 0.58 9.9 0.8 6.0 6 1 1 7 7 7 0 Homeobox associated leucine zipper EF-hand_1 PF00036.27 CAR28783.1 - 1.3e-25 86.6 15.4 4.5e-08 31.8 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CAR28783.1 - 3.4e-25 87.9 12.3 1.9e-14 53.5 1.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CAR28783.1 - 2.3e-22 76.7 11.6 1.9e-07 30.3 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 CAR28783.1 - 2.2e-19 68.8 13.3 2.6e-11 42.9 0.6 3.9 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 CAR28783.1 - 8e-17 59.7 12.9 3.6e-05 22.9 0.0 4.2 4 1 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 CAR28783.1 - 5.4e-08 32.6 0.9 0.0028 17.5 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CAR28783.1 - 5.7e-08 32.4 2.6 0.00099 18.8 0.1 2.5 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CAR28783.1 - 0.0026 17.7 1.6 0.26 11.3 0.1 2.2 1 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region MerR-DNA-bind PF09278.6 CAR28783.1 - 0.059 13.7 1.1 30 5.1 0.1 3.3 3 1 0 3 3 3 0 MerR, DNA binding VCBS PF13517.1 CAR28783.1 - 0.078 13.3 4.7 0.3 11.4 0.0 2.6 3 0 0 3 3 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella MgtE_N PF03448.12 CAR28783.1 - 0.079 13.2 0.2 0.079 13.2 0.2 2.2 3 0 0 3 3 3 0 MgtE intracellular N domain Caleosin PF05042.8 CAR28783.1 - 0.088 12.3 0.8 1.1 8.8 0.0 2.6 1 1 2 3 3 3 0 Caleosin related protein FG-GAP PF01839.18 CAR28783.1 - 7.5 6.3 6.0 7.3 6.4 0.1 2.4 2 0 0 2 2 2 0 FG-GAP repeat KOW PF00467.24 CAR28784.1 - 0.0023 17.5 0.5 0.0049 16.5 0.3 1.6 1 0 0 1 1 1 1 KOW motif HIT PF01230.18 CAR28785.1 - 2.4e-20 72.8 0.7 5.6e-20 71.7 0.1 1.8 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 CAR28785.1 - 6.1e-18 65.1 1.4 6.1e-18 65.1 0.9 2.1 2 1 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding zf-BED PF02892.10 CAR28785.1 - 0.0014 18.3 0.5 0.003 17.2 0.3 1.5 1 0 0 1 1 1 1 BED zinc finger zf-C2H2_4 PF13894.1 CAR28785.1 - 0.022 15.0 1.1 0.057 13.7 0.4 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger AAA PF00004.24 CAR28786.1 - 7.3e-43 145.9 0.0 1.4e-42 144.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CAR28786.1 - 8.1e-07 29.2 2.2 2e-05 24.6 0.0 3.1 2 2 2 4 4 4 1 AAA ATPase domain AAA_5 PF07728.9 CAR28786.1 - 2.4e-06 27.3 0.1 6e-05 22.7 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CAR28786.1 - 1.5e-05 24.9 0.5 3.9e-05 23.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CAR28786.1 - 3.3e-05 24.0 0.1 0.0039 17.3 0.0 2.6 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 CAR28786.1 - 5.5e-05 22.3 0.0 9.9e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CAR28786.1 - 0.00021 20.9 0.2 0.00044 19.9 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 CAR28786.1 - 0.00036 21.3 1.3 0.0014 19.3 0.1 2.5 2 1 0 2 2 2 1 AAA domain UPF0079 PF02367.12 CAR28786.1 - 0.0014 18.2 0.0 0.0028 17.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 CAR28786.1 - 0.0015 18.7 0.0 0.0035 17.4 0.0 1.7 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.12 CAR28786.1 - 0.0031 16.9 0.1 0.0068 15.8 0.1 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 CAR28786.1 - 0.0042 16.9 0.1 0.016 15.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 CAR28786.1 - 0.005 15.6 0.1 0.0088 14.8 0.1 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 CAR28786.1 - 0.0055 15.8 0.1 0.011 14.8 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 CAR28786.1 - 0.0076 15.6 0.8 0.064 12.6 0.3 2.3 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.1 CAR28786.1 - 0.0078 16.1 0.3 0.021 14.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 CAR28786.1 - 0.01 15.4 0.3 0.01 15.4 0.2 1.8 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 CAR28786.1 - 0.011 15.6 0.0 0.028 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 CAR28786.1 - 0.02 14.0 1.3 0.049 12.7 0.0 2.3 3 0 0 3 3 3 0 KaiC Zeta_toxin PF06414.7 CAR28786.1 - 0.023 13.7 2.1 0.097 11.7 0.0 2.5 2 1 1 3 3 3 0 Zeta toxin PhoH PF02562.11 CAR28786.1 - 0.027 13.7 0.2 0.055 12.6 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.21 CAR28786.1 - 0.047 13.1 0.2 0.19 11.1 0.0 2.0 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.1 CAR28786.1 - 0.055 13.7 0.0 0.055 13.7 0.0 2.8 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.17 CAR28786.1 - 0.056 12.3 1.7 0.68 8.7 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_3 PF07726.6 CAR28786.1 - 0.076 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 CAR28786.1 - 0.084 12.4 4.3 0.72 9.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 CAR28786.1 - 0.092 12.3 0.1 0.32 10.6 0.0 1.9 1 1 1 2 2 2 0 NACHT domain Apc15p PF05841.6 CAR28786.1 - 1.8 9.3 11.9 3.3 8.4 8.3 1.4 1 0 0 1 1 1 0 Apc15p protein Herpes_DNAp_acc PF04929.7 CAR28786.1 - 2 7.3 8.5 3 6.7 5.9 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Fib_alpha PF08702.5 CAR28786.1 - 2.2 8.3 6.4 6.5 6.8 4.3 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.14 CAR28786.1 - 3 5.6 4.9 3.9 5.2 3.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 CAR28786.1 - 3.1 7.3 8.2 5.8 6.4 5.7 1.4 1 0 0 1 1 1 0 IncA protein Hexapep PF00132.19 CAR28787.1 - 7.9e-07 28.3 8.2 0.033 13.6 0.2 3.9 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 CAR28787.1 - 4.2e-05 23.6 0.0 7.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.7 CAR28787.1 - 0.0062 15.1 0.0 0.01 14.4 0.0 1.4 1 0 0 1 1 1 1 L-fucokinase NTP_transferase PF00483.18 CAR28787.1 - 0.015 14.5 0.0 0.032 13.5 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyl transferase UbiA PF01040.13 CAR28788.1 - 7.9e-24 84.2 15.8 1.1e-23 83.8 11.0 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family MitMem_reg PF13012.1 CAR28789.1 - 5.1e-39 132.9 2.4 8.7e-39 132.1 0.8 2.0 2 1 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 CAR28789.1 - 8.2e-27 93.2 0.0 1.9e-26 92.0 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease ATP_bind_1 PF03029.12 CAR28790.1 - 5.5e-80 268.3 0.0 7.5e-80 267.8 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 CAR28790.1 - 0.00046 19.0 0.0 0.00081 18.2 0.0 1.3 1 0 0 1 1 1 1 ArgK protein AAA_17 PF13207.1 CAR28790.1 - 0.0026 18.5 3.5 0.0045 17.8 0.0 2.7 2 2 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CAR28790.1 - 0.0031 17.2 0.0 0.0059 16.3 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_10 PF12846.2 CAR28790.1 - 0.007 15.8 0.0 0.0077 15.7 0.0 1.3 1 1 0 1 1 1 1 AAA-like domain MMR_HSR1 PF01926.18 CAR28790.1 - 0.0071 16.2 0.4 0.051 13.5 0.0 2.4 2 2 0 2 2 2 1 50S ribosome-binding GTPase CbiA PF01656.18 CAR28790.1 - 0.0083 15.5 0.0 0.05 13.0 0.0 2.1 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.1 CAR28790.1 - 0.02 15.1 0.4 0.9 9.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CAR28790.1 - 0.035 13.9 0.1 0.09 12.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 CAR28790.1 - 0.089 12.5 0.0 0.28 10.8 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 CAR28790.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain TBCA PF02970.11 CAR28792.1 - 1e-27 96.0 8.5 1.2e-27 95.8 5.9 1.0 1 0 0 1 1 1 1 Tubulin binding cofactor A DUF2100 PF09873.4 CAR28792.1 - 0.012 15.0 0.6 0.013 14.9 0.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2100) Troponin PF00992.15 CAR28792.1 - 0.091 12.8 7.5 0.14 12.2 5.2 1.4 1 1 0 1 1 1 0 Troponin Orthopox_A5L PF06193.6 CAR28792.1 - 0.11 12.4 2.8 0.31 10.9 1.9 1.6 1 1 0 1 1 1 0 Orthopoxvirus A5L protein-like Lipoprotein_20 PF13942.1 CAR28792.1 - 0.11 12.0 1.7 0.14 11.6 1.2 1.1 1 0 0 1 1 1 0 YfhG lipoprotein FadA PF09403.5 CAR28792.1 - 0.14 12.2 6.1 0.16 11.9 4.2 1.1 1 0 0 1 1 1 0 Adhesion protein FadA TMF_TATA_bd PF12325.3 CAR28792.1 - 0.23 11.2 6.6 0.3 10.8 4.6 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF342 PF03961.8 CAR28792.1 - 0.37 9.1 3.3 0.39 9.0 2.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Fzo_mitofusin PF04799.8 CAR28792.1 - 0.43 9.9 2.0 0.5 9.7 1.4 1.2 1 0 0 1 1 1 0 fzo-like conserved region IncA PF04156.9 CAR28792.1 - 0.62 9.6 6.1 0.97 8.9 4.2 1.3 1 1 0 1 1 1 0 IncA protein zf-C4H2 PF10146.4 CAR28792.1 - 0.95 9.4 4.5 1.2 9.1 3.1 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein DUF4463 PF14703.1 CAR28792.1 - 1.4 9.5 4.3 6.4 7.3 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4463) Pkinase PF00069.20 CAR28794.1 - 9.6e-57 192.0 2.9 3.6e-55 186.9 2.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR28794.1 - 2.8e-19 69.1 0.0 7e-19 67.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Ycf1 PF05758.7 CAR28794.1 - 0.0019 15.9 3.8 0.0027 15.5 2.7 1.1 1 0 0 1 1 1 1 Ycf1 MIP-T3 PF10243.4 CAR28794.1 - 0.007 14.9 17.5 0.013 13.9 12.1 1.4 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Kinase-like PF14531.1 CAR28794.1 - 0.068 12.1 0.0 0.15 10.9 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Oxidored_FMN PF00724.15 CAR28795.1 - 2.4e-109 365.4 0.0 2.8e-109 365.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family TFIID-31kDa PF02291.10 CAR28796.1 - 1.6e-54 183.1 0.0 1.9e-54 182.9 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit ChAPs PF09295.5 CAR28797.1 - 3.9e-167 555.9 0.1 4.9e-167 555.6 0.1 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 CAR28797.1 - 2.4e-06 27.1 0.5 0.011 15.3 0.0 3.0 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 CAR28797.1 - 7.3e-06 25.5 0.4 0.038 13.9 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CAR28797.1 - 9.3e-05 22.7 2.6 11 6.9 0.0 4.9 4 2 2 6 6 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 CAR28797.1 - 0.0012 18.4 0.0 0.39 10.5 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 CAR28797.1 - 0.0023 18.2 0.1 24 5.6 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 CAR28797.1 - 0.003 17.0 0.0 1.7 8.3 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 CAR28797.1 - 0.0059 17.2 4.0 1.9 9.2 0.1 4.0 4 1 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 CAR28797.1 - 0.0079 16.3 1.8 0.67 10.1 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CAR28797.1 - 0.027 14.3 0.2 3.5 7.5 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 CAR28797.1 - 0.047 13.9 0.0 0.19 12.0 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 CAR28797.1 - 0.047 13.5 0.2 11 6.1 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_hydro_76 PF03663.9 CAR28798.1 - 1.2e-149 498.6 13.2 1.6e-149 498.3 9.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 RGS PF00615.14 CAR28799.1 - 3.8e-05 23.7 1.4 8.4e-05 22.6 0.4 1.9 2 1 0 2 2 2 1 Regulator of G protein signaling domain Leader_CPA1 PF08252.6 CAR28800.1 - 5.5e-15 54.2 1.2 6e-15 54.0 0.8 1.0 1 0 0 1 1 1 1 arg-2/CPA1 leader peptide GATase PF00117.23 CAR28801.1 - 7.3e-46 156.0 0.0 1e-45 155.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 CAR28801.1 - 4.7e-44 149.0 0.0 9.4e-44 148.0 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.8 CAR28801.1 - 1.2e-07 31.4 0.2 2.1e-05 24.0 0.1 3.0 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.19 CAR28801.1 - 0.0032 16.9 0.0 0.0057 16.1 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family Ank PF00023.25 CAR28801.1 - 0.077 12.8 0.0 4.3 7.3 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat Glyco_hydro_46 PF01374.13 CAR28801.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 46 RCC1 PF00415.13 CAR28802.1 - 3e-22 78.5 1.8 8.2e-08 32.3 0.0 4.8 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CAR28802.1 - 1.6e-15 56.1 14.1 8e-09 34.8 0.2 5.4 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 CAR28802.1 - 1e-07 31.9 0.4 4.4e-06 26.6 0.1 3.1 2 1 1 3 3 3 1 BTB/POZ domain SNF2_N PF00176.18 CAR28803.1 - 9.8e-81 270.8 0.8 1.7e-80 270.0 0.6 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 CAR28803.1 - 3.3e-41 139.7 4.7 3.3e-41 139.7 3.3 2.9 3 0 0 3 3 3 1 SLIDE HAND PF09110.6 CAR28803.1 - 6.2e-36 123.2 13.3 6.2e-36 123.2 9.2 3.7 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 CAR28803.1 - 1.6e-16 59.9 0.0 1.4e-15 56.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAR28803.1 - 4.8e-08 32.6 0.0 1.8e-07 30.7 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CAR28803.1 - 0.044 13.9 0.2 0.29 11.2 0.1 2.5 1 1 0 1 1 1 0 AAA domain Ribonuclease_3 PF00636.21 CAR28804.1 - 1e-20 74.2 0.1 1.2e-19 70.8 0.0 2.4 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 CAR28804.1 - 3.3e-16 59.3 0.0 8.2e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 CAR28804.1 - 7.1e-06 26.5 0.0 1.7e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif Amidohydro_4 PF13147.1 CAR28805.1 - 5.8e-14 52.7 0.0 4.2e-13 49.9 0.0 2.4 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 CAR28805.1 - 2.7e-13 50.2 0.2 7.7e-08 32.3 0.0 3.0 2 1 1 3 3 3 2 Amidohydrolase family Amidohydro_5 PF13594.1 CAR28805.1 - 1.5e-11 43.8 6.6 1.8e-11 43.6 2.9 2.3 2 0 0 2 2 2 1 Amidohydrolase Urease_alpha PF00449.15 CAR28805.1 - 0.0057 16.7 0.1 0.02 15.0 0.1 2.0 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain D-aminoacyl_C PF07908.7 CAR28805.1 - 0.073 12.3 0.0 0.16 11.2 0.0 1.6 1 0 0 1 1 1 0 D-aminoacylase, C-terminal region NTP_transf_2 PF01909.18 CAR28805.1 - 0.15 12.4 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain DUF382 PF04037.8 CAR28806.1 - 7.1e-53 177.8 0.5 1.9e-52 176.4 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 CAR28806.1 - 4.3e-20 70.8 2.5 9.1e-20 69.7 1.8 1.6 1 0 0 1 1 1 1 PSP Tower PF09121.5 CAR28806.1 - 0.68 9.9 3.3 0.58 10.1 0.6 2.2 2 0 0 2 2 2 0 Tower Strabismus PF06638.6 CAR28807.1 - 0.022 13.0 3.0 0.024 12.9 2.1 1.0 1 0 0 1 1 1 0 Strabismus protein DHC_N1 PF08385.7 CAR28807.1 - 0.029 12.7 1.0 0.03 12.7 0.7 1.0 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 DUF4618 PF15397.1 CAR28807.1 - 0.04 13.2 2.6 0.042 13.1 1.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) ScpA_ScpB PF02616.9 CAR28807.1 - 0.058 12.9 0.3 0.062 12.8 0.2 1.1 1 0 0 1 1 1 0 ScpA/B protein Transposase_24 PF03004.9 CAR28807.1 - 0.06 13.2 1.3 0.068 13.0 0.9 1.1 1 0 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) Syntaxin-6_N PF09177.6 CAR28807.1 - 0.16 12.3 1.3 0.19 12.1 0.9 1.3 1 0 0 1 1 1 0 Syntaxin 6, N-terminal AKNA PF12443.3 CAR28807.1 - 0.23 11.5 2.4 0.27 11.2 1.7 1.1 1 0 0 1 1 1 0 AT-hook-containing transcription factor DUF2034 PF10356.4 CAR28808.1 - 4.4e-54 182.4 0.0 5.3e-54 182.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 CAR28808.1 - 0.003 17.3 0.0 0.65 9.8 0.0 2.2 2 0 0 2 2 2 2 Restriction endonuclease Mito_carr PF00153.22 CAR28809.1 - 2.5e-27 94.3 6.4 2.5e-11 43.1 0.0 3.5 2 1 2 4 4 4 4 Mitochondrial carrier protein TPT PF03151.11 CAR28810.1 - 2e-23 82.7 6.6 2e-23 82.7 4.6 2.8 3 1 0 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 CAR28810.1 - 2.8e-06 27.3 21.3 2.8e-05 24.1 2.5 3.4 4 0 0 4 4 4 2 EamA-like transporter family UAA PF08449.6 CAR28810.1 - 0.00088 18.2 5.7 0.00088 18.2 3.9 2.5 2 1 0 2 2 2 2 UAA transporter family SART-1 PF03343.8 CAR28811.1 - 4.4e-47 160.7 48.9 1.9e-23 82.6 14.8 4.0 1 1 2 3 3 3 3 SART-1 family Glyco_transf_64 PF09258.5 CAR28811.1 - 0.15 11.1 0.8 0.36 9.9 0.3 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 64 domain Nop PF01798.13 CAR28812.1 - 4.6e-59 198.0 0.6 1.7e-58 196.1 0.4 2.0 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 CAR28812.1 - 5.6e-27 93.2 0.1 1.2e-26 92.2 0.1 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 CAR28812.1 - 7.7e-19 67.6 1.3 7.7e-19 67.6 0.9 2.9 2 1 1 3 3 3 1 NOP5NT (NUC127) domain CTP_transf_1 PF01148.15 CAR28813.1 - 5.2e-21 75.4 9.1 1.3e-18 67.6 3.4 2.1 1 1 1 2 2 2 2 Cytidylyltransferase family Ribosomal_L18ae PF01775.12 CAR28814.1 - 2e-57 192.4 1.2 2e-57 192.4 0.8 1.4 2 0 0 2 2 2 1 Ribosomal L18ae/LX protein domain DUF1057 PF06342.7 CAR28814.1 - 0.043 12.6 0.0 0.065 12.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) DUF3141 PF11339.3 CAR28815.1 - 0.099 10.9 1.8 0.75 8.0 0.0 2.6 2 1 0 3 3 3 0 Protein of unknown function (DUF3141) Baculo_PEP_C PF04513.7 CAR28815.1 - 0.21 11.4 4.3 0.51 10.1 0.1 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DDE_Tnp_IS240 PF13610.1 CAR28815.1 - 0.36 10.7 2.9 0.56 10.1 0.1 2.3 2 1 1 3 3 3 0 DDE domain Cation_efflux PF01545.16 CAR28816.1 - 1.2e-80 270.6 4.0 1.7e-80 270.1 2.8 1.2 1 0 0 1 1 1 1 Cation efflux family NDUF_C2 PF06374.6 CAR28816.1 - 0.028 14.4 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) SUN PF03856.8 CAR28817.1 - 1.1e-79 267.3 22.1 1.2e-79 267.1 15.3 1.0 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Bac_rhodopsin PF01036.13 CAR28818.1 - 3.1e-74 249.0 22.6 3.6e-74 248.8 15.7 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF912 PF06024.7 CAR28818.1 - 0.12 12.4 0.7 5.4 7.1 0.0 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4131 PF13567.1 CAR28818.1 - 0.29 10.5 14.8 1.5 8.1 4.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) RDD PF06271.7 CAR28818.1 - 8.5 6.2 25.8 79 3.1 8.6 3.4 2 1 1 3 3 3 0 RDD family COX6B PF02297.12 CAR28819.1 - 7.3e-23 80.3 6.3 9.3e-23 80.0 4.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Sigma70_ECF PF07638.6 CAR28819.1 - 0.037 13.6 0.1 0.045 13.4 0.0 1.1 1 0 0 1 1 1 0 ECF sigma factor Pet191_N PF10203.4 CAR28819.1 - 0.038 14.0 2.0 0.14 12.1 1.4 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 AMP-binding PF00501.23 CAR28820.1 - 2.8e-75 253.2 0.0 4.1e-75 252.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CAR28820.1 - 0.062 14.2 0.0 0.14 13.1 0.0 1.6 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain RRM_1 PF00076.17 CAR28821.1 - 3.2e-25 87.5 0.1 3.9e-14 52.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR28821.1 - 6.8e-20 70.8 0.1 1.3e-10 41.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR28821.1 - 2.5e-10 40.0 0.1 4.5e-06 26.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) bcl-2I13 PF12201.3 CAR28821.1 - 0.0099 15.3 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 1 Bcl2-interacting killer, BH3-domain containing Limkain-b1 PF11608.3 CAR28821.1 - 0.013 15.2 0.0 1.9 8.3 0.0 2.3 2 0 0 2 2 2 0 Limkain b1 Glyco_transf_8 PF01501.15 CAR28822.1 - 3.6e-07 29.7 5.8 3.6e-07 29.7 4.0 2.4 2 1 0 2 2 2 1 Glycosyl transferase family 8 zf-RING_2 PF13639.1 CAR28823.1 - 1.1e-08 34.6 7.1 1.1e-08 34.6 4.9 2.0 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 CAR28823.1 - 1.4e-07 31.4 2.7 3.6e-07 30.1 1.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 CAR28823.1 - 1.1e-05 25.2 3.9 1.1e-05 25.2 2.7 2.0 2 0 0 2 2 2 1 FANCL C-terminal domain zf-Apc11 PF12861.2 CAR28823.1 - 0.00066 19.4 1.2 0.0015 18.3 0.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 CAR28823.1 - 0.062 13.3 10.4 0.012 15.6 4.3 2.1 2 0 0 2 2 2 0 RING-variant domain zf-C3HC4_2 PF13923.1 CAR28823.1 - 0.13 12.2 13.4 0.07 13.1 5.7 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 CAR28823.1 - 0.15 12.0 6.6 0.34 10.9 4.6 1.6 1 0 0 1 1 1 0 RING-like domain zf-UDP PF14569.1 CAR28823.1 - 0.46 10.2 1.8 9.2 6.0 0.2 2.6 1 1 1 2 2 2 0 Zinc-binding RING-finger zf-C3HC4 PF00097.20 CAR28823.1 - 0.55 9.9 13.6 0.059 13.0 5.6 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CAR28823.1 - 3.5 7.3 10.0 2.6 7.7 3.5 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CAR28823.1 - 5.9 6.5 7.1 96 2.6 4.8 2.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain SAM_decarbox PF01536.11 CAR28824.1 - 8.5e-112 373.0 3.1 9.9e-112 372.8 2.1 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase CSTF2_hinge PF14327.1 CAR28824.1 - 0.12 12.4 0.6 22 5.2 0.1 2.5 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 Tbf5 PF06331.7 CAR28824.1 - 0.17 11.6 0.5 19 5.0 0.0 2.9 3 0 0 3 3 3 0 Transcription factor TFIIH complex subunit Tfb5 Pyridoxal_deC PF00282.14 CAR28825.1 - 7e-53 179.3 0.0 1e-52 178.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Ala_racemase_N PF01168.15 CAR28827.1 - 3.8e-39 134.4 0.0 4.7e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Adaptin_N PF01602.15 CAR28828.1 - 1.1e-104 350.6 9.4 1.4e-104 350.3 6.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 CAR28828.1 - 1.1e-05 25.6 0.0 4.2e-05 23.8 0.0 2.0 1 0 0 1 1 1 1 Adaptin C-terminal domain Alpha_adaptin_C PF02296.11 CAR28828.1 - 1.6e-05 24.8 0.0 6.6e-05 22.8 0.0 2.1 1 1 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain ATP-synt_8 PF00895.15 CAR28828.1 - 2 8.6 5.5 0.49 10.6 0.3 2.7 2 0 0 2 2 2 0 ATP synthase protein 8 Rep_fac_C PF08542.6 CAR28829.1 - 1.6e-20 72.8 1.0 4.3e-20 71.4 0.0 2.2 3 0 0 3 3 3 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 CAR28829.1 - 8.3e-13 48.3 0.1 3.1e-12 46.4 0.0 1.9 2 1 0 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.24 CAR28829.1 - 8.8e-08 32.4 0.2 4.5e-07 30.1 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.8 CAR28829.1 - 2.7e-05 23.7 0.1 0.00013 21.4 0.1 2.0 2 0 0 2 2 2 1 DNA polymerase III, delta subunit Rad17 PF03215.10 CAR28829.1 - 5.9e-05 21.9 0.1 0.0091 14.7 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 CAR28829.1 - 0.00031 20.8 0.3 0.0025 17.9 0.1 2.3 2 2 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CAR28829.1 - 0.0041 17.1 0.2 0.015 15.3 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 CAR28829.1 - 0.0074 16.3 0.1 0.73 9.8 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_10 PF12846.2 CAR28829.1 - 0.013 14.9 0.3 0.067 12.6 0.2 1.9 1 1 0 1 1 1 0 AAA-like domain NAD_binding_6 PF08030.7 CAR28829.1 - 0.03 14.2 0.0 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 Ferric reductase NAD binding domain FtsK_SpoIIIE PF01580.13 CAR28829.1 - 0.065 12.6 0.1 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_5 PF07728.9 CAR28829.1 - 0.23 11.2 1.5 0.74 9.5 0.2 2.5 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Ribosomal_L16 PF00252.13 CAR28830.1 - 6.1e-34 116.6 0.2 9.9e-34 115.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Peptidase_M20 PF01546.23 CAR28831.1 - 1.3e-26 93.2 0.0 1.8e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CAR28831.1 - 3.9e-14 52.3 0.0 7.7e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Cnd2 PF05786.9 CAR28832.1 - 1.7e-126 423.5 31.3 4.6e-126 422.1 21.7 1.7 1 1 0 1 1 1 1 Condensin complex subunit 2 Rad21_Rec8_N PF04825.8 CAR28832.1 - 0.11 12.4 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 N terminus of Rad21 / Rec8 like protein FAD_binding_3 PF01494.14 CAR28833.1 - 6.4e-20 71.5 0.0 3e-19 69.3 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 CAR28833.1 - 0.00025 21.4 0.0 0.0026 18.1 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 CAR28833.1 - 0.00067 18.5 0.1 0.0058 15.4 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.19 CAR28833.1 - 0.00094 18.1 0.0 0.011 14.7 0.1 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 CAR28833.1 - 0.0022 16.8 0.0 0.0038 16.1 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 CAR28833.1 - 0.0028 17.6 0.0 0.0064 16.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 CAR28833.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 CAR28833.1 - 0.016 14.1 0.1 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 CAR28833.1 - 0.076 11.4 0.0 0.13 10.7 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Peptidase_M41 PF01434.13 CAR28834.1 - 2.9e-69 232.7 0.1 6.4e-69 231.6 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CAR28834.1 - 7.9e-41 139.3 1.7 4e-40 137.0 0.0 2.6 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CAR28834.1 - 9.7e-05 22.4 0.0 9.7e-05 22.4 0.0 2.8 3 2 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 CAR28834.1 - 9.9e-05 22.4 0.1 0.037 14.1 0.1 3.0 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 CAR28834.1 - 0.00051 18.8 0.0 0.00093 18.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 CAR28834.1 - 0.00057 20.6 0.0 0.0028 18.4 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CAR28834.1 - 0.0021 17.7 2.3 0.0076 15.9 1.6 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 CAR28834.1 - 0.0032 17.1 0.1 0.012 15.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CAR28834.1 - 0.004 16.5 1.0 0.075 12.4 0.4 2.4 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CAR28834.1 - 0.0041 16.5 0.0 0.011 15.2 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein PhoH PF02562.11 CAR28834.1 - 0.0041 16.3 0.6 0.3 10.2 0.2 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_14 PF13173.1 CAR28834.1 - 0.0044 16.9 0.0 0.065 13.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CAR28834.1 - 0.005 15.9 0.0 0.005 15.9 0.0 2.3 3 0 0 3 3 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 CAR28834.1 - 0.031 14.1 0.5 0.11 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 CAR28834.1 - 0.034 13.3 0.1 0.091 11.9 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 CAR28834.1 - 0.062 13.6 0.0 0.062 13.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain Peptidase_M50B PF13398.1 CAR28834.1 - 0.27 10.5 1.0 0.32 10.3 0.1 1.5 2 0 0 2 2 1 0 Peptidase M50B-like AAA_28 PF13521.1 CAR28834.1 - 0.34 10.8 0.0 0.34 10.8 0.0 2.6 3 0 0 3 3 2 0 AAA domain Pex14_N PF04695.8 CAR28834.1 - 0.42 10.6 6.4 12 5.9 2.6 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DDRGK PF09756.4 CAR28834.1 - 1.3 8.3 16.4 2.8 7.2 6.4 2.2 2 0 0 2 2 2 0 DDRGK domain Cyclin_N PF00134.18 CAR28835.1 - 2.3e-12 46.6 0.4 4.2e-12 45.7 0.3 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.14 CAR28835.1 - 0.004 16.9 0.0 0.0074 16.0 0.0 1.5 1 0 0 1 1 1 1 Transcription factor TFIIB repeat ATP-synt_ab PF00006.20 CAR28836.1 - 9.9e-68 227.8 0.0 1.4e-67 227.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CAR28836.1 - 1.6e-24 86.5 1.5 2.7e-24 85.7 0.1 2.2 3 0 0 3 3 3 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CAR28836.1 - 4.4e-18 65.2 2.3 7.7e-18 64.4 0.6 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 CAR28836.1 - 0.0024 17.7 0.3 0.0092 15.8 0.2 2.1 1 1 0 1 1 1 1 HAS barrel domain AAA_25 PF13481.1 CAR28836.1 - 0.045 13.1 0.0 0.086 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Glyco_hydro_65m PF03632.10 CAR28837.1 - 1.2e-95 320.3 2.2 8.8e-95 317.5 0.5 2.6 2 1 0 2 2 2 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 CAR28837.1 - 1.7e-40 138.9 0.1 3e-40 138.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.10 CAR28837.1 - 5.6e-11 42.3 0.8 2.6e-10 40.2 0.1 2.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, C-terminal domain TB2_DP1_HVA22 PF03134.14 CAR28838.1 - 2.2e-30 104.2 5.6 3.1e-30 103.7 3.8 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Peptidase_M50B PF13398.1 CAR28838.1 - 0.14 11.5 7.2 0.18 11.2 4.3 1.6 1 1 1 2 2 2 0 Peptidase M50B-like DUF2721 PF11026.3 CAR28838.1 - 0.26 10.9 1.1 0.97 9.0 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) Adaptin_N PF01602.15 CAR28839.1 - 4.9e-103 345.2 20.9 7.8e-103 344.5 14.5 1.3 1 1 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 CAR28839.1 - 4.7e-10 39.8 1.5 1.2e-09 38.5 1.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 CAR28839.1 - 0.0063 16.7 1.0 0.35 11.1 0.0 3.8 3 2 1 4 4 4 1 HEAT repeats Arrestin_C PF02752.17 CAR28840.1 - 4e-16 59.3 0.0 4e-16 59.3 0.0 3.6 4 1 0 4 4 4 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CAR28840.1 - 0.012 15.4 0.0 0.076 12.8 0.0 2.2 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Got1 PF04178.7 CAR28841.1 - 1.2e-32 112.4 15.8 1.6e-32 112.0 10.9 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Terpene_synth_C PF03936.11 CAR28841.1 - 0.14 11.4 0.1 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain HLH PF00010.21 CAR28842.1 - 4.3e-13 48.7 0.6 9.3e-13 47.6 0.4 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain OmpH PF03938.9 CAR28842.1 - 3.4e-06 27.0 9.9 7.8e-06 25.9 6.9 1.6 1 1 0 1 1 1 1 Outer membrane protein (OmpH-like) Spt20 PF12090.3 CAR28842.1 - 0.00046 19.5 8.3 0.089 12.1 3.8 2.3 2 0 0 2 2 2 2 Spt20 family DUF2347 PF09804.4 CAR28842.1 - 0.0021 17.3 2.6 0.0021 17.3 1.8 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) Med15 PF09606.5 CAR28842.1 - 0.068 11.3 31.1 0.083 11.0 16.5 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Band_3_cyto PF07565.8 CAR28842.1 - 0.073 12.5 5.7 0.18 11.2 2.1 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain AAA_23 PF13476.1 CAR28842.1 - 0.099 12.9 14.4 0.046 14.0 8.0 1.8 2 0 0 2 2 2 0 AAA domain Suf PF05843.9 CAR28842.1 - 0.14 11.8 14.6 0.061 13.0 5.7 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Pex14_N PF04695.8 CAR28842.1 - 0.67 10.0 17.7 0.58 10.2 6.9 2.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3371 PF11851.3 CAR28842.1 - 1.6 9.3 25.1 1.8 9.2 6.8 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3371) V_ATPase_I PF01496.14 CAR28842.1 - 1.8 6.2 9.3 2.8 5.6 6.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ctr PF04145.10 CAR28842.1 - 1.9 8.5 3.3 2.5 8.1 0.4 2.2 2 0 0 2 2 2 0 Ctr copper transporter family SPX PF03105.14 CAR28842.1 - 2.3 7.9 17.2 5.1 6.7 11.9 1.6 1 1 0 1 1 1 0 SPX domain Plasmodium_Vir PF05795.6 CAR28842.1 - 2.8 7.0 5.6 1.1 8.4 1.0 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Baculo_PP31 PF05311.6 CAR28842.1 - 5.4 6.1 12.2 1.4 8.1 5.3 2.0 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) PAT1 PF09770.4 CAR28842.1 - 5.7 5.0 33.7 1.8 6.7 16.3 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF4175 PF13779.1 CAR28842.1 - 9.6 3.7 29.5 0.13 9.9 13.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) Mannosyl_trans3 PF11051.3 CAR28843.1 - 6.9e-74 248.6 0.0 1.5e-73 247.5 0.0 1.6 2 0 0 2 2 2 1 Mannosyltransferase putative Glyco_transf_8 PF01501.15 CAR28843.1 - 0.0098 15.2 0.0 0.021 14.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 8 zf-HC5HC2H_2 PF13832.1 CAR28844.1 - 6.6e-32 109.7 6.2 6.6e-32 109.7 4.3 2.7 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CAR28844.1 - 1.7e-28 98.5 4.0 1.7e-28 98.5 2.8 3.6 2 1 1 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.1 CAR28844.1 - 8e-14 50.6 4.0 8e-14 50.6 2.8 2.6 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 CAR28844.1 - 5.3e-11 42.0 19.8 8.5e-10 38.1 3.3 3.0 2 0 0 2 2 2 2 PHD-finger EPL1 PF10513.4 CAR28844.1 - 3.5e-09 37.0 1.6 3.9e-09 36.9 0.2 1.8 2 0 0 2 2 2 1 Enhancer of polycomb-like C1_1 PF00130.17 CAR28844.1 - 0.0023 17.6 12.2 0.004 16.8 0.2 2.9 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.6 CAR28844.1 - 0.0043 17.0 16.4 0.09 12.7 4.8 3.0 2 0 0 2 2 2 2 RING-like domain Prok-RING_1 PF14446.1 CAR28844.1 - 0.014 15.1 16.0 0.18 11.5 2.7 2.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_2 PF13639.1 CAR28844.1 - 1.9 8.4 18.7 0.87 9.4 2.4 2.8 2 1 0 2 2 2 0 Ring finger domain zf-RING_2 PF13639.1 CAR28845.1 - 4.6 7.1 13.9 0.35 10.7 2.2 3.7 5 0 0 5 5 5 0 Ring finger domain Pkinase PF00069.20 CAR28846.1 - 8.1e-64 215.2 0.0 8.1e-64 215.2 0.0 2.1 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR28846.1 - 7e-35 120.3 0.0 1.6e-34 119.1 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 CAR28846.1 - 1.1e-23 82.6 15.0 7.6e-16 57.6 3.5 4.1 3 0 0 3 3 3 2 Hr1 repeat C1_1 PF00130.17 CAR28846.1 - 2e-18 65.8 35.2 2e-10 40.2 10.0 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 CAR28846.1 - 6.5e-11 42.5 3.1 2.5e-10 40.7 2.2 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain Lgl_C PF08596.5 CAR28847.1 - 3.5e-129 430.7 0.0 7.6e-129 429.6 0.0 1.6 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 CAR28847.1 - 0.034 14.0 4.1 0.22 11.4 0.1 4.2 5 0 0 5 5 5 0 WD domain, G-beta repeat Cid2 PF09774.4 CAR28848.1 - 2.5e-32 112.0 1.3 3e-32 111.8 0.9 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 DUF932 PF06067.6 CAR28848.1 - 0.091 12.0 0.1 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF932) IDO PF01231.13 CAR28849.1 - 6e-156 519.1 0.0 7e-156 518.9 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase tRNA-synt_His PF13393.1 CAR28850.1 - 2.2e-39 135.3 0.0 3e-38 131.6 0.0 2.0 1 1 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 CAR28850.1 - 1.4e-17 63.8 0.0 3.6e-17 62.4 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CAR28850.1 - 3.2e-14 52.6 0.0 6.1e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 CAR28850.1 - 0.0048 15.7 0.0 0.54 8.9 0.0 2.5 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 CAR28850.1 - 0.0086 15.2 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) HHH_5 PF14520.1 CAR28850.1 - 0.23 11.6 2.4 21 5.3 0.2 3.0 3 0 0 3 3 3 0 Helix-hairpin-helix domain AIM24 PF01987.12 CAR28851.1 - 3.1e-08 33.3 0.0 4.2e-07 29.6 0.0 2.2 1 1 0 1 1 1 1 Mitochondrial biogenesis AIM24 UNC-50 PF05216.8 CAR28852.1 - 1.3e-88 296.1 24.1 1.5e-88 295.9 16.7 1.0 1 0 0 1 1 1 1 UNC-50 family PLDc PF00614.17 CAR28854.1 - 1.9e-15 56.1 2.4 5.4e-08 32.3 0.2 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 CAR28854.1 - 4.9e-10 39.2 0.0 1.4e-06 28.0 0.0 2.8 2 1 0 2 2 2 2 PLD-like domain PX PF00787.19 CAR28854.1 - 0.0022 17.7 3.3 0.0066 16.2 0.2 3.2 4 0 0 4 4 4 1 PX domain ANTH PF07651.11 CAR28855.1 - 4e-65 219.3 0.0 4e-65 219.3 0.0 2.1 2 0 0 2 2 2 1 ANTH domain ENTH PF01417.15 CAR28855.1 - 7.8e-07 29.0 0.1 2.2e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 ENTH domain MPC PF03650.8 CAR28856.1 - 2.7e-47 159.6 0.1 3.2e-47 159.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) 4HBT_3 PF13622.1 CAR28857.1 - 7.6e-30 104.4 0.0 9.4e-30 104.1 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 CAR28857.1 - 8.3e-28 96.6 0.3 1.4e-20 73.2 0.1 3.2 2 1 0 2 2 2 2 Acyl-CoA thioesterase ATP-grasp_2 PF08442.5 CAR28859.1 - 8.6e-72 240.7 0.3 1.3e-71 240.1 0.2 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 CAR28859.1 - 5e-26 91.1 0.1 2.3e-25 88.9 0.1 2.2 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.1 CAR28859.1 - 0.00028 20.1 0.1 0.00079 18.6 0.1 1.8 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 CAR28859.1 - 0.0011 18.5 0.0 0.0035 16.9 0.0 1.8 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 CAR28859.1 - 0.09 12.5 0.0 0.23 11.1 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain Oxidored_FMN PF00724.15 CAR28860.1 - 2.7e-111 371.8 0.0 3.2e-111 371.6 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family RWD PF05773.17 CAR28861.1 - 3.8e-21 75.0 5.4 1.2e-20 73.5 3.8 1.8 1 1 0 1 1 1 1 RWD domain ENTH PF01417.15 CAR28862.1 - 1.1e-31 109.2 0.3 1.9e-31 108.5 0.2 1.4 1 0 0 1 1 1 1 ENTH domain PGA2 PF07543.7 CAR28862.1 - 0.014 15.1 5.3 0.014 15.1 3.7 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 PEHE PF15275.1 CAR28862.1 - 6.8 7.1 12.2 1.1 9.7 5.0 2.2 1 1 1 2 2 2 0 PEHE domain Pro_isomerase PF00160.16 CAR28863.1 - 6.6e-45 153.0 0.0 7.3e-45 152.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RNA_polI_A14 PF08203.6 CAR28864.1 - 5.5e-24 84.1 0.8 5.6e-24 84.1 0.0 1.4 2 0 0 2 2 2 1 Yeast RNA polymerase I subunit RPA14 Semialdhyde_dhC PF02774.13 CAR28865.1 - 3.6e-45 154.1 0.0 5.1e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 CAR28865.1 - 6.8e-32 110.3 0.0 1.3e-31 109.3 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.11 CAR28865.1 - 0.014 15.9 0.0 0.029 14.8 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Saccharop_dh PF03435.13 CAR28865.1 - 0.014 14.4 0.2 0.027 13.4 0.0 1.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase DapB_N PF01113.15 CAR28865.1 - 0.059 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Methyltransf_16 PF10294.4 CAR28866.1 - 2.7e-07 30.2 0.1 0.00029 20.3 0.0 2.3 1 1 1 2 2 2 2 Putative methyltransferase SAC3_GANP PF03399.11 CAR28867.1 - 5.9e-55 186.0 0.4 1.6e-54 184.6 0.3 1.8 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family SAC3 PF12209.3 CAR28867.1 - 2.8e-15 56.1 1.8 2.8e-15 56.1 1.3 3.3 4 0 0 4 4 4 1 Leucine permease transcriptional regulator helical domain Nha1_C PF08619.5 CAR28868.1 - 6e-78 263.0 44.9 8e-78 262.6 31.1 1.2 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 CAR28868.1 - 2.4e-77 260.0 21.2 2.9e-77 259.7 14.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family AA_permease PF00324.16 CAR28869.1 - 5e-78 262.5 37.2 8.8e-78 261.7 25.8 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CAR28869.1 - 3.8e-37 127.8 42.3 1.7e-36 125.6 29.3 1.8 1 1 0 1 1 1 1 Amino acid permease TPR_19 PF14559.1 CAR28870.1 - 7.7e-05 22.9 7.0 0.0067 16.7 0.2 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 CAR28870.1 - 8.3e-05 22.4 2.3 0.026 14.6 0.4 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 CAR28870.1 - 0.00021 20.8 2.3 1.5 8.5 1.8 3.9 3 1 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 CAR28870.1 - 0.00024 20.7 1.1 0.48 10.4 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 CAR28870.1 - 0.0024 17.7 5.6 0.24 11.3 1.0 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 CAR28870.1 - 0.0026 17.8 1.7 0.49 10.5 0.1 3.2 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CAR28870.1 - 0.0036 16.9 0.0 0.6 10.0 0.2 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_21 PF09976.4 CAR28870.1 - 0.01 15.7 0.4 1.3 8.9 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 CAR28870.1 - 0.012 16.2 0.0 0.24 12.0 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 CAR28870.1 - 0.013 15.1 1.6 19 5.0 0.5 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 CAR28870.1 - 0.015 15.8 0.9 1.9 9.3 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 CAR28870.1 - 0.11 12.3 0.7 30 4.7 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat SH3_9 PF14604.1 CAR28871.1 - 1.8e-13 49.8 0.1 5.6e-13 48.2 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CAR28871.1 - 3.4e-13 48.7 1.1 4.5e-13 48.3 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 CAR28871.1 - 2.1e-06 27.1 0.0 4.4e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Cwf_Cwc_15 PF04889.7 CAR28872.1 - 1.8e-19 70.4 43.0 1.7e-09 37.7 24.9 3.0 1 1 1 2 2 2 2 Cwf15/Cwc15 cell cycle control protein Nop53 PF07767.6 CAR28872.1 - 0.0052 15.8 21.0 0.0052 15.8 14.5 1.9 1 1 1 2 2 2 1 Nop53 (60S ribosomal biogenesis) Prothymosin PF03247.9 CAR28872.1 - 0.0074 16.4 23.5 0.012 15.7 16.3 1.3 1 0 0 1 1 1 1 Prothymosin/parathymosin family Daxx PF03344.10 CAR28872.1 - 0.045 12.2 19.7 0.052 12.0 13.6 1.0 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 CAR28872.1 - 0.068 12.5 17.3 0.085 12.2 12.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Nop14 PF04147.7 CAR28872.1 - 0.089 10.6 19.3 0.1 10.5 13.4 1.1 1 0 0 1 1 1 0 Nop14-like family Adaptin_binding PF10199.4 CAR28872.1 - 0.09 13.0 18.9 0.035 14.3 11.6 1.4 2 0 0 2 2 1 0 Alpha and gamma adaptin binding protein p34 CENP-B_dimeris PF09026.5 CAR28872.1 - 0.38 11.0 16.7 0.65 10.2 11.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.8 CAR28872.1 - 0.38 10.3 17.5 0.6 9.6 12.1 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2890 PF11081.3 CAR28872.1 - 0.4 10.7 16.5 0.66 10.0 11.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) PI3K_1B_p101 PF10486.4 CAR28872.1 - 0.43 8.1 4.2 0.44 8.0 2.9 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF506 PF04720.7 CAR28872.1 - 0.57 9.7 6.4 0.67 9.5 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF506) CDC45 PF02724.9 CAR28872.1 - 0.62 8.0 18.4 0.73 7.7 12.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Pro_CA PF00484.14 CAR28872.1 - 1.1 9.2 3.5 1.6 8.6 2.4 1.4 1 0 0 1 1 1 0 Carbonic anhydrase Vfa1 PF08432.5 CAR28872.1 - 1.2 9.1 16.3 1.7 8.6 11.3 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nucleoplasmin PF03066.10 CAR28872.1 - 1.2 8.5 16.4 2.1 7.8 11.3 1.5 1 0 0 1 1 1 0 Nucleoplasmin Sporozoite_P67 PF05642.6 CAR28872.1 - 3.1 5.5 10.7 3.5 5.3 7.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Hid1 PF12722.2 CAR28872.1 - 7.3 4.1 12.2 7.8 4.0 8.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SLS PF14611.1 CAR28873.1 - 4.9e-24 84.9 0.4 9e-24 84.0 0.3 1.5 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator Mid2 PF04478.7 CAR28874.1 - 8.8 5.7 6.3 0.67 9.3 0.2 2.0 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Pro_dh PF01619.13 CAR28875.1 - 3.4e-62 210.2 0.0 4.7e-62 209.7 0.0 1.2 1 0 0 1 1 1 1 Proline dehydrogenase ATP_bind_4 PF01902.12 CAR28876.1 - 3.1e-37 128.0 0.0 8.7e-37 126.6 0.0 1.7 1 1 0 1 1 1 1 ATP-binding region Ribonuc_L-PSP PF01042.16 CAR28876.1 - 5.9e-18 64.7 0.0 2.9e-09 36.7 0.0 2.6 2 0 0 2 2 2 2 Endoribonuclease L-PSP Sec1 PF00995.18 CAR28878.1 - 1.4e-97 327.7 1.5 1.7e-97 327.4 1.0 1.1 1 0 0 1 1 1 1 Sec1 family DUF3113 PF11310.3 CAR28878.1 - 0.023 14.3 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3113) Glyco_hydro_81 PF03639.8 CAR28879.1 - 6.1e-240 797.9 4.9 7.4e-240 797.6 3.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 DUF4477 PF14780.1 CAR28880.1 - 0.063 12.6 5.1 2.5 7.4 1.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4477) Spermine_synth PF01564.12 CAR28881.1 - 9.6e-88 293.2 0.0 1.2e-87 292.9 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 CAR28881.1 - 0.00028 21.4 0.0 0.00049 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAR28881.1 - 0.0029 17.3 0.0 0.012 15.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAR28881.1 - 0.0061 17.0 0.1 0.015 15.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CAR28881.1 - 0.01 15.8 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain WD40 PF00400.27 CAR28882.1 - 1.7e-08 34.0 2.6 0.002 17.9 0.7 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat CPSF_A PF03178.10 CAR28882.1 - 1.6e-05 24.1 0.1 9.5e-05 21.6 0.0 2.2 3 0 0 3 3 3 1 CPSF A subunit region Lactonase PF10282.4 CAR28882.1 - 0.0083 15.2 0.0 0.02 14.0 0.0 1.6 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller Microcephalin PF12258.3 CAR28883.1 - 0.0059 15.6 0.6 0.0071 15.3 0.4 1.1 1 0 0 1 1 1 1 Microcephalin protein MitMem_reg PF13012.1 CAR28883.1 - 0.066 13.2 0.1 0.091 12.8 0.0 1.3 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Sec5 PF15469.1 CAR28884.1 - 3.1e-51 173.6 4.2 5.6e-51 172.8 1.2 2.8 1 1 1 2 2 2 1 Exocyst complex component Sec5 COG2 PF06148.6 CAR28884.1 - 0.0021 17.9 2.0 0.0021 17.9 1.4 2.8 2 1 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Utp12 PF04003.7 CAR28884.1 - 0.084 12.7 4.3 0.1 12.4 0.2 3.2 4 0 0 4 4 4 0 Dip2/Utp12 Family DUF1798 PF08807.5 CAR28884.1 - 0.88 9.3 8.0 4.4 7.0 0.2 3.5 3 0 0 3 3 3 0 Bacterial domain of unknown function (DUF1798) LSM PF01423.17 CAR28885.1 - 1.3e-13 50.2 0.8 1.6e-13 50.0 0.6 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CAR28885.1 - 0.07 13.0 0.3 0.089 12.7 0.2 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Pep3_Vps18 PF05131.9 CAR28886.1 - 1.1e-39 135.2 0.0 3.8e-39 133.4 0.0 2.0 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 CAR28886.1 - 2.5e-09 36.8 4.8 2.5e-09 36.8 3.4 2.6 2 0 0 2 2 2 1 Region in Clathrin and VPS Vps39_2 PF10367.4 CAR28886.1 - 3.5e-06 27.1 4.8 3.5e-06 27.1 1.0 2.8 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.1 CAR28886.1 - 3.9e-05 23.3 5.3 0.00012 21.8 3.7 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CAR28886.1 - 0.075 12.7 11.3 0.25 11.1 7.8 2.0 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 CAR28886.1 - 0.13 11.9 3.8 0.4 10.3 2.6 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TFIID_30kDa PF03540.8 CAR28887.1 - 3.3e-26 90.8 0.1 5e-26 90.2 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit CDC37_N PF03234.9 CAR28888.1 - 2.6e-64 216.8 6.8 2.6e-64 216.8 4.7 3.7 2 1 2 4 4 4 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 CAR28888.1 - 1.9e-45 154.4 9.2 1.9e-45 154.4 6.4 2.7 2 1 1 3 3 3 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 CAR28888.1 - 6.1e-23 80.5 6.8 6.1e-23 80.5 4.7 2.9 3 0 0 3 3 3 1 Cdc37 C terminal domain DUF2415 PF10313.4 CAR28889.1 - 2.6e-21 75.0 0.4 2.6e-21 75.0 0.3 2.5 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) Stb3 PF10330.4 CAR28890.1 - 1.1e-31 108.3 0.0 2.3e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 Putative Sin3 binding protein Nucleoplasmin PF03066.10 CAR28890.1 - 0.37 10.3 11.2 0.88 9.0 7.8 1.8 1 0 0 1 1 1 0 Nucleoplasmin TRAP_alpha PF03896.11 CAR28890.1 - 1.8 7.4 7.2 3.5 6.5 5.0 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Stm1_N PF09598.5 CAR28891.1 - 9.5e-18 64.6 9.2 9.5e-18 64.6 6.4 4.1 3 1 0 3 3 3 1 Stm1 GRP PF07172.6 CAR28891.1 - 7.3 7.1 14.8 0.053 13.9 2.9 2.5 2 1 0 2 2 2 0 Glycine rich protein family NUDIX PF00293.23 CAR28892.1 - 3.7e-14 52.5 0.0 2e-13 50.1 0.0 2.0 1 1 0 1 1 1 1 NUDIX domain Mem_trans PF03547.13 CAR28893.1 - 6.5e-56 189.2 0.1 1e-55 188.5 0.1 1.3 1 1 0 1 1 1 1 Membrane transport protein TEX19 PF15553.1 CAR28893.1 - 0.064 13.1 0.3 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 Testis-expressed protein 19 VIT1 PF01988.14 CAR28893.1 - 0.28 10.6 3.4 1.5 8.2 0.2 2.6 2 1 0 2 2 2 0 VIT family Reticulon PF02453.12 CAR28893.1 - 0.28 10.7 5.8 0.61 9.6 1.1 3.0 3 0 0 3 3 3 0 Reticulon AMP-binding PF00501.23 CAR28894.1 - 5.8e-89 298.3 0.1 7.2e-89 298.0 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CAR28894.1 - 1.3e-18 67.7 0.1 8.3e-18 65.1 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Sec7 PF01369.15 CAR28895.1 - 3.7e-67 225.6 0.6 1.2e-66 224.0 0.4 1.9 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 CAR28895.1 - 6.4e-54 181.8 2.2 6.4e-54 181.8 1.5 3.2 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 CAR28895.1 - 4e-28 96.7 4.4 2.1e-27 94.4 0.5 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) GTP_CH_N PF12471.3 CAR28896.1 - 4.4e-85 284.2 0.0 7.2e-85 283.5 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 CAR28896.1 - 3.2e-18 65.5 0.0 4.7e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II HSP20 PF00011.16 CAR28897.1 - 3.6e-10 39.6 0.0 3.6e-10 39.6 0.0 2.4 3 0 0 3 3 3 1 Hsp20/alpha crystallin family Ycf1 PF05758.7 CAR28897.1 - 0.012 13.3 8.0 0.026 12.2 0.9 2.1 2 0 0 2 2 2 0 Ycf1 Pex14_N PF04695.8 CAR28897.1 - 0.25 11.3 10.5 0.2 11.6 2.0 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Plasmodium_Vir PF05795.6 CAR28897.1 - 7.1 5.7 7.6 1 8.4 1.4 1.9 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Med15 PF09606.5 CAR28897.1 - 7.7 4.5 31.3 11 4.0 21.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal GTP_EFTU PF00009.22 CAR28898.1 - 6e-46 156.2 0.7 1.2e-45 155.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CAR28898.1 - 1.5e-24 86.0 0.4 1.5e-24 86.0 0.3 2.4 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CAR28898.1 - 1.9e-07 31.0 0.3 6.9e-07 29.2 0.2 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CAR28898.1 - 0.0011 18.9 0.0 0.0035 17.2 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase CDC27 PF09507.5 CAR28898.1 - 1.3 8.1 28.6 2 7.5 19.8 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ycf1 PF05758.7 CAR28898.1 - 1.4 6.5 9.6 2 6.0 6.6 1.2 1 0 0 1 1 1 0 Ycf1 IPK PF03770.11 CAR28899.1 - 5.1e-54 182.9 0.2 6.3e-54 182.6 0.2 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase CRCB PF02537.10 CAR28900.1 - 1.5e-31 108.7 17.9 9.9e-21 73.8 4.4 2.6 3 0 0 3 3 3 2 CrcB-like protein DUF4560 PF15118.1 CAR28900.1 - 0.87 9.4 6.1 0.44 10.3 1.5 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4560) Ribosomal_S6e PF01092.14 CAR28901.1 - 8.2e-64 212.9 0.4 1.8e-63 211.8 0.3 1.6 1 0 0 1 1 1 1 Ribosomal protein S6e Pyr_redox_2 PF07992.9 CAR28902.1 - 9.8e-42 143.1 0.7 1.5e-41 142.4 0.5 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 CAR28902.1 - 2.5e-36 124.0 1.6 7.6e-35 119.2 0.1 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 CAR28902.1 - 3.1e-19 69.1 8.9 1.2e-18 67.2 1.1 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CAR28902.1 - 5.7e-14 52.6 0.4 3.4e-11 43.6 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CAR28902.1 - 5e-08 31.8 6.5 0.025 13.0 0.0 4.0 3 1 1 4 4 4 3 HI0933-like protein K_oxygenase PF13434.1 CAR28902.1 - 8.7e-07 28.1 0.0 2.3e-06 26.7 0.0 1.7 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 CAR28902.1 - 1e-06 28.4 0.9 0.00096 18.7 0.0 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.2 CAR28902.1 - 1.8e-06 27.3 0.0 3.5e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 CAR28902.1 - 4.3e-06 25.8 6.7 0.00014 20.8 0.9 2.6 3 0 0 3 3 3 2 Glucose inhibited division protein A DAO PF01266.19 CAR28902.1 - 0.00063 18.7 1.4 0.00063 18.7 1.0 3.7 3 1 1 4 4 4 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CAR28902.1 - 0.0046 16.0 3.3 0.17 10.9 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_7 PF13241.1 CAR28902.1 - 0.0064 16.7 0.1 2.1 8.6 0.0 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 CAR28902.1 - 0.0075 15.4 2.1 0.4 9.8 0.0 3.1 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 CAR28902.1 - 0.02 14.5 4.2 0.024 14.2 0.1 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 CAR28902.1 - 0.068 12.5 0.2 0.15 11.4 0.2 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.15 CAR28902.1 - 0.14 12.2 0.5 5.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 CAR28902.1 - 0.43 10.3 4.6 3.1 7.5 0.1 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding ThiF PF00899.16 CAR28902.1 - 0.57 9.9 2.9 0.51 10.1 0.2 2.2 2 0 0 2 2 2 0 ThiF family SLAC1 PF03595.12 CAR28903.1 - 6e-70 235.5 31.1 6.8e-70 235.3 21.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel UL2 PF08196.6 CAR28903.1 - 0.0055 16.4 1.3 2.9 7.7 0.1 2.8 2 0 0 2 2 2 2 UL2 protein HR_lesion PF05514.6 CAR28903.1 - 0.052 13.3 0.6 0.052 13.3 0.4 2.6 2 0 0 2 2 2 0 HR-like lesion-inducing MFS_1 PF07690.11 CAR28904.1 - 5.8e-47 160.1 34.3 3.2e-43 147.7 11.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CAR28904.1 - 3.4e-18 65.4 30.6 6.3e-17 61.2 6.5 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter DUF2436 PF10365.4 CAR28904.1 - 0.033 13.8 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2436) NOGCT PF08155.6 CAR28905.1 - 4.4e-28 96.7 1.1 4.4e-28 96.7 0.8 2.1 2 0 0 2 2 2 1 NOGCT (NUC087) domain NOG1 PF06858.9 CAR28905.1 - 1.1e-26 92.4 0.3 2.3e-26 91.4 0.2 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 CAR28905.1 - 5.2e-16 58.6 0.0 1.1e-15 57.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CAR28905.1 - 3.1e-08 33.0 0.0 6e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 CAR28905.1 - 0.00024 20.3 0.1 0.00048 19.3 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CAR28905.1 - 0.0079 16.6 0.0 0.023 15.2 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 CAR28905.1 - 0.036 13.8 0.0 10 5.9 0.0 2.7 1 1 1 2 2 2 0 Dynamin family AAA_16 PF13191.1 CAR28905.1 - 0.065 13.2 0.0 1.3 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.1 CAR28905.1 - 1.5 9.1 5.8 7.9 6.7 0.0 2.8 2 1 0 2 2 2 0 AAA domain Sec62 PF03839.11 CAR28906.1 - 2.5e-61 206.9 0.0 3.3e-61 206.5 0.0 1.1 1 0 0 1 1 1 1 Translocation protein Sec62 MARVEL PF01284.18 CAR28906.1 - 0.00096 18.9 0.1 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Membrane-associating domain FixP_N PF14715.1 CAR28906.1 - 0.25 10.7 3.1 4.8 6.6 0.1 2.3 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Dynamin_N PF00350.18 CAR28907.1 - 5.6e-17 62.0 1.1 1.4e-16 60.7 0.1 2.2 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 CAR28907.1 - 2.6e-08 33.8 0.1 1.3e-07 31.6 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CAR28907.1 - 1.7e-07 30.8 0.1 3.2e-06 26.7 0.1 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 CAR28907.1 - 0.0057 17.1 0.1 0.09 13.2 0.0 3.0 2 1 1 3 3 3 1 Miro-like protein PPV_E1_C PF00519.12 CAR28907.1 - 0.01 14.5 0.0 0.019 13.6 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase Abhydrolase_1 PF00561.15 CAR28908.1 - 6.8e-21 74.8 0.0 1.1e-20 74.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CAR28908.1 - 3.8e-12 46.5 0.0 6.3e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CAR28908.1 - 7e-09 35.5 0.0 3.8e-08 33.2 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 CAR28908.1 - 0.04 13.6 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 Cutinase DUF2669 PF10876.3 CAR28908.1 - 0.044 13.4 0.1 0.11 12.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2669) DUF915 PF06028.6 CAR28908.1 - 0.087 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Transglut_core PF01841.14 CAR28909.1 - 2.5e-12 46.9 0.1 6.6e-12 45.6 0.1 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.10 CAR28909.1 - 2.4e-09 36.7 1.9 2.4e-09 36.7 1.3 1.8 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain Zn_Tnp_IS1595 PF12760.2 CAR28909.1 - 6.3 6.7 9.4 24 4.8 5.6 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain tRNA-synt_1b PF00579.20 CAR28910.1 - 4.5e-71 239.3 0.0 6e-71 238.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Romo1 PF10247.4 CAR28911.1 - 3.2e-28 97.7 6.5 4.2e-28 97.3 4.5 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 LRS4 PF10422.4 CAR28912.1 - 0.0021 17.4 3.2 0.0026 17.1 2.2 1.1 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 DUF2681 PF10883.3 CAR28912.1 - 0.0022 18.1 0.2 0.0022 18.1 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2681) Peptidase_M56 PF05569.6 CAR28912.1 - 0.019 13.9 0.4 0.024 13.6 0.3 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 WD40 PF00400.27 CAR28913.1 - 0.0041 16.9 0.2 0.0041 16.9 0.1 4.3 5 0 0 5 5 5 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CAR28913.1 - 0.023 13.4 0.4 2.3 6.8 0.0 2.7 2 2 1 3 3 3 0 Nup133 N terminal like PAXNEB PF05625.6 CAR28914.1 - 7.3e-105 350.7 0.2 8.5e-105 350.5 0.1 1.0 1 0 0 1 1 1 1 PAXNEB protein Lactamase_B_2 PF12706.2 CAR28915.1 - 1.3e-32 112.8 2.5 2e-32 112.3 1.7 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CAR28915.1 - 3.8e-11 42.9 0.2 6.4e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain VWA_3 PF13768.1 CAR28915.1 - 0.083 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain PsbN PF02468.10 CAR28915.1 - 0.66 9.6 2.4 1.3 8.6 1.6 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) Pantoate_transf PF02548.10 CAR28916.1 - 4.6e-97 324.2 0.1 5.3e-97 324.0 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 CAR28916.1 - 1.1e-05 24.7 0.1 3.4e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Asp_Glu_race PF01177.17 CAR28916.1 - 0.029 14.2 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 Asp/Glu/Hydantoin racemase tRNA-synt_2 PF00152.15 CAR28917.1 - 2.5e-114 381.5 0.1 3.5e-114 381.0 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CAR28917.1 - 7.1e-06 25.7 0.2 1.3e-05 24.9 0.2 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 CAR28917.1 - 5.2e-05 22.8 0.1 0.037 13.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.15 CAR28917.1 - 0.0029 16.8 0.3 0.095 11.8 0.1 2.9 2 1 0 2 2 2 1 tRNA synthetases class II core domain (F) WD40 PF00400.27 CAR28918.1 - 1.7e-34 116.4 7.0 2.9e-09 36.4 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 CAR28918.1 - 6.6e-06 24.5 0.1 0.0019 16.4 0.0 2.7 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 CAR28918.1 - 0.00069 19.3 0.0 0.036 13.7 0.0 3.0 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 CAR28918.1 - 0.0008 17.8 0.0 0.02 13.2 0.0 2.0 1 1 1 2 2 2 1 Cytochrome D1 heme domain Coatomer_WDAD PF04053.9 CAR28918.1 - 0.066 11.9 0.0 0.76 8.5 0.0 2.3 1 1 1 2 2 2 0 Coatomer WD associated region RCC1_2 PF13540.1 CAR28918.1 - 1.5 8.5 4.8 15 5.3 0.5 3.3 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat UMP1 PF05348.6 CAR28919.1 - 7.2e-38 129.4 0.1 8.4e-38 129.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 GYF PF02213.11 CAR28920.1 - 1.4e-20 72.6 0.6 3.2e-20 71.4 0.4 1.7 1 0 0 1 1 1 1 GYF domain Sec66 PF09802.4 CAR28921.1 - 1e-73 246.7 2.7 1.2e-73 246.5 1.9 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 NPL4 PF05021.10 CAR28922.1 - 2.7e-125 417.6 0.0 3.6e-125 417.1 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 CAR28922.1 - 1.5e-69 232.3 1.3 2.3e-69 231.7 0.9 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 CAR28922.1 - 3.1e-06 27.3 0.0 9.4e-06 25.8 0.0 1.9 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 NigD PF12667.2 CAR28922.1 - 0.083 12.6 0.1 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 NigD-like protein Metallophos PF00149.23 CAR28923.1 - 7.4e-05 22.2 0.1 0.00017 21.0 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Hpt PF01627.18 CAR28924.1 - 1.3e-12 47.5 0.4 2.5e-12 46.5 0.0 1.6 2 0 0 2 2 2 1 Hpt domain Strep_67kDa_ant PF06100.6 CAR28924.1 - 0.076 11.3 0.0 0.099 10.9 0.0 1.2 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family MgsA_C PF12002.3 CAR28925.1 - 3.7e-51 173.1 0.0 7.2e-51 172.2 0.0 1.4 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 CAR28925.1 - 6.6e-15 55.4 0.0 1.2e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CAR28925.1 - 2e-14 53.2 0.0 4.3e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CAR28925.1 - 8.7e-09 35.3 0.0 1.7e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CAR28925.1 - 5.9e-08 32.5 0.0 1.6e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CAR28925.1 - 2.6e-07 30.7 0.2 0.00018 21.5 0.0 2.6 1 1 1 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 CAR28925.1 - 2.1e-06 27.9 0.6 4.2e-05 23.6 0.4 2.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 CAR28925.1 - 2.5e-05 24.2 0.0 0.00014 21.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.21 CAR28925.1 - 3.7e-05 23.2 0.0 0.00035 20.0 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 CAR28925.1 - 5.6e-05 22.3 0.1 0.12 11.5 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 CAR28925.1 - 0.00056 20.2 0.0 0.0023 18.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CAR28925.1 - 0.0007 19.7 0.1 0.016 15.3 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_17 PF13207.1 CAR28925.1 - 0.00097 19.9 0.0 0.0024 18.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CAR28925.1 - 0.0021 17.5 0.3 0.12 11.7 0.0 2.3 1 1 1 2 2 2 1 AAA-like domain NB-ARC PF00931.17 CAR28925.1 - 0.0022 16.9 0.0 0.0036 16.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain ABC_tran PF00005.22 CAR28925.1 - 0.0025 18.1 0.1 0.0063 16.8 0.0 1.9 1 1 1 2 2 1 1 ABC transporter DUF815 PF05673.8 CAR28925.1 - 0.0041 16.0 0.0 0.007 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.1 CAR28925.1 - 0.0049 16.4 0.0 0.0093 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CAR28925.1 - 0.0052 16.2 0.0 0.0084 15.5 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Viral_helicase1 PF01443.13 CAR28925.1 - 0.0094 15.4 0.3 0.023 14.2 0.0 1.8 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.6 CAR28925.1 - 0.0094 15.5 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CAR28925.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 CAR28925.1 - 0.015 15.2 0.0 0.038 13.9 0.0 1.8 2 0 0 2 2 1 0 50S ribosome-binding GTPase Sigma54_activ_2 PF14532.1 CAR28925.1 - 0.018 15.0 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Sgf11 PF08209.6 CAR28925.1 - 0.027 13.7 0.1 0.062 12.6 0.0 1.6 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) ResIII PF04851.10 CAR28925.1 - 0.028 14.2 1.7 0.31 10.8 0.3 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_33 PF13671.1 CAR28925.1 - 0.034 14.0 0.0 0.073 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 CAR28925.1 - 0.035 13.3 0.0 0.068 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_30 PF13604.1 CAR28925.1 - 0.035 13.6 0.1 0.36 10.3 0.0 2.3 2 1 0 2 2 1 0 AAA domain NACHT PF05729.7 CAR28925.1 - 0.071 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.1 CAR28925.1 - 0.086 12.2 0.0 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CAR28925.1 - 0.1 12.2 0.0 0.29 10.7 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase AAA_19 PF13245.1 CAR28925.1 - 0.14 11.9 0.1 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Hydrolase_6 PF13344.1 CAR28926.1 - 3.1e-28 97.6 0.0 1e-27 95.9 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CAR28926.1 - 1.1e-12 47.4 0.0 2.1e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CAR28926.1 - 4.8e-11 43.4 0.0 1.5e-10 41.8 0.0 1.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CAR28926.1 - 0.011 15.9 0.1 0.1 12.8 0.2 2.3 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Glyco_transf_22 PF03901.12 CAR28927.1 - 3.3e-86 289.9 23.8 4.2e-86 289.5 16.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Adenylsucc_synt PF00709.16 CAR28928.1 - 3.8e-164 546.3 0.0 4.3e-164 546.1 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase POP1 PF06978.6 CAR28929.1 - 7.5e-64 214.8 12.3 2.1e-63 213.3 8.5 1.8 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 CAR28929.1 - 2.3e-31 107.4 0.5 5.1e-31 106.3 0.3 1.6 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T_C PF08669.6 CAR28929.1 - 0.05 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain GDPD PF03009.12 CAR28930.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Amidohydro_1 PF01979.15 CAR28931.1 - 1e-50 173.2 0.0 1.2e-50 173.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 CAR28931.1 - 1e-07 31.5 0.6 7.4e-05 22.1 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 CAR28931.1 - 2.8e-05 24.2 0.1 0.027 14.5 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 CAR28931.1 - 4e-05 23.3 0.0 9.3e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Ssu72 PF04722.8 CAR28932.1 - 2.5e-89 297.7 0.0 2.9e-89 297.6 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Helicase_C PF00271.26 CAR28932.1 - 0.12 12.2 0.1 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Peptidase_C54 PF03416.14 CAR28933.1 - 3.5e-86 288.8 0.0 4.5e-86 288.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 G-patch PF01585.18 CAR28934.1 - 3.3e-11 42.7 3.3 3.3e-11 42.7 2.3 2.3 2 0 0 2 2 2 1 G-patch domain Nop14 PF04147.7 CAR28934.1 - 0.17 9.7 49.7 0.3 8.9 34.4 1.3 1 0 0 1 1 1 0 Nop14-like family Mem_trans PF03547.13 CAR28934.1 - 1.1 7.5 1.8 1.2 7.3 1.3 1.2 1 0 0 1 1 1 0 Membrane transport protein SAPS PF04499.10 CAR28934.1 - 5.3 5.5 16.1 9.5 4.7 11.2 1.5 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SID PF11778.3 CAR28935.1 - 2e-49 167.0 1.3 2e-49 167.0 0.9 3.9 3 0 0 3 3 3 2 Septation initiation DnaJ PF00226.26 CAR28936.1 - 7.4e-26 89.6 0.4 3.3e-25 87.5 0.3 2.2 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.3 CAR28936.1 - 3.6e-09 36.5 2.4 8.1e-09 35.3 1.7 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CAR28936.1 - 2.5e-06 27.4 2.1 5.3e-06 26.4 1.5 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CAR28936.1 - 0.00028 20.9 0.8 0.0013 18.8 0.6 2.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 CAR28936.1 - 0.011 16.0 1.1 0.039 14.3 0.7 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type AKAP95 PF04988.7 CAR28936.1 - 0.014 15.1 5.8 0.014 15.1 4.0 2.2 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.1 CAR28936.1 - 0.32 11.4 3.0 0.23 11.8 0.4 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger GST_C PF00043.20 CAR28937.1 - 1.5e-19 69.7 0.0 3.2e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CAR28937.1 - 5.1e-15 55.3 0.0 1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CAR28937.1 - 3.5e-10 39.7 0.0 6.7e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CAR28937.1 - 1.1e-09 38.3 0.0 2e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CAR28937.1 - 0.0055 16.5 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Activator_LAG-3 PF11498.3 CAR28937.1 - 1.6 7.3 25.9 2.3 6.8 18.0 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 CDI PF02234.14 CAR28937.1 - 2.8 7.7 0.0 2.8 7.7 0.0 3.1 3 0 0 3 3 3 0 Cyclin-dependent kinase inhibitor Elongin_A PF06881.6 CAR28938.1 - 1.4e-18 67.2 17.1 1.9e-16 60.4 1.4 3.0 1 1 2 3 3 3 2 RNA polymerase II transcription factor SIII (Elongin) subunit A DDE_Tnp_4 PF13359.1 CAR28938.1 - 0.19 11.3 3.4 1.2 8.7 0.0 2.5 2 1 1 3 3 3 0 DDE superfamily endonuclease CRAL_TRIO PF00650.15 CAR28939.1 - 2.4e-39 134.3 0.0 3.5e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CAR28939.1 - 3e-12 46.4 0.4 3e-12 46.4 0.3 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain EXOSC1 PF10447.4 CAR28940.1 - 8.2e-33 112.2 0.1 2.1e-32 110.9 0.0 1.7 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 S1 PF00575.18 CAR28940.1 - 0.017 15.1 0.0 2.3 8.3 0.0 2.6 2 0 0 2 2 2 0 S1 RNA binding domain Globin PF00042.17 CAR28942.1 - 2.5e-07 30.9 0.1 2.6e-06 27.7 0.0 2.6 2 1 0 2 2 2 1 Globin Med16 PF11635.3 CAR28943.1 - 7.5e-203 675.5 10.0 9e-203 675.3 6.9 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 Ytp1 PF10355.4 CAR28944.1 - 4.6e-74 249.0 16.5 7.6e-74 248.3 11.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) Ni_hydr_CYTB PF01292.15 CAR28944.1 - 6.4 6.1 27.0 11 5.3 5.1 4.2 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 Peptidase_S8 PF00082.17 CAR28945.1 - 8.3e-60 202.3 0.3 2e-59 201.1 0.2 1.6 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 CAR28945.1 - 8e-24 83.2 0.5 1.8e-23 82.1 0.3 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain DUF912 PF06024.7 CAR28945.1 - 0.54 10.3 2.0 0.85 9.7 0.0 2.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Peptidase_C1_2 PF03051.10 CAR28946.1 - 4.2e-160 533.0 0.8 4.8e-160 532.8 0.6 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 CAR28946.1 - 1.2e-05 25.2 0.1 0.19 11.5 0.0 2.5 2 1 0 2 2 2 2 Papain family cysteine protease Fe_hyd_lg_C PF02906.9 CAR28947.1 - 7.1e-62 209.2 0.0 9.3e-62 208.8 0.0 1.1 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Cys_Met_Meta_PP PF01053.15 CAR28948.1 - 4.4e-67 226.0 0.0 1.3e-66 224.5 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 CAR28948.1 - 2.7e-05 23.1 0.0 4.2e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 CAR28948.1 - 0.0037 16.2 0.0 0.02 13.8 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class I and II G6PD_C PF02781.11 CAR28949.1 - 8e-127 422.1 0.0 1e-126 421.7 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 CAR28949.1 - 1.7e-61 207.6 0.0 4.5e-61 206.2 0.0 1.7 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain LIM PF00412.17 CAR28950.1 - 1.4e-36 124.3 50.6 1.1e-14 54.2 3.5 4.4 4 0 0 4 4 4 4 LIM domain RhoGAP PF00620.22 CAR28950.1 - 4.3e-35 120.5 0.0 1e-34 119.3 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain DUF164 PF02591.10 CAR28950.1 - 7.4 6.4 8.3 32 4.4 0.0 3.3 3 0 0 3 3 3 0 Putative zinc ribbon domain ATG2_CAD PF13329.1 CAR28951.1 - 1.8e-34 118.6 0.1 1.8e-34 118.6 0.1 2.9 3 0 0 3 3 3 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 CAR28951.1 - 4.3e-26 90.9 0.1 9.2e-26 89.8 0.1 1.6 1 0 0 1 1 1 1 ATG C terminal domain DUF508 PF04370.7 CAR28951.1 - 0.024 14.2 1.0 0.061 12.9 0.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Sir1 PF11603.3 CAR28952.1 - 7.7e-11 42.2 1.9 3.3e-09 36.9 0.0 2.9 3 1 0 3 3 3 2 Regulatory protein Sir1 PALP PF00291.20 CAR28953.1 - 2.4e-60 204.3 0.0 3.1e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CLN3 PF02487.12 CAR28953.1 - 7e-06 25.0 0.0 1.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 CLN3 protein SIS_2 PF13580.1 CAR28953.1 - 0.087 12.5 0.0 1.2 8.8 0.0 2.5 3 0 0 3 3 3 0 SIS domain DUF601 PF04642.7 CAR28954.1 - 1.5 8.0 5.5 1.9 7.7 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF601 TFIIA PF03153.8 CAR28954.1 - 1.8 8.4 8.3 1.9 8.2 5.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Homeobox PF00046.24 CAR28955.1 - 2e-07 30.4 0.3 4.1e-07 29.5 0.2 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CAR28955.1 - 2.2e-06 27.2 0.2 9.9e-06 25.1 0.1 2.2 2 0 0 2 2 2 1 Homeobox KN domain mRNA_cap_C PF03919.10 CAR28955.1 - 0.018 15.3 0.9 0.65 10.3 0.1 2.3 2 0 0 2 2 2 0 mRNA capping enzyme, C-terminal domain Homez PF11569.3 CAR28955.1 - 0.053 12.5 0.4 0.12 11.4 0.0 1.8 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez MAT_Alpha1 PF04769.7 CAR28956.1 - 9.1e-09 34.9 0.1 1.8e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 ANTH PF07651.11 CAR28957.1 - 1.8e-67 226.9 0.0 2.6e-67 226.4 0.0 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 CAR28957.1 - 0.0082 16.0 0.0 0.03 14.1 0.0 1.9 1 1 0 1 1 1 1 ENTH domain SUI1 PF01253.17 CAR28958.1 - 3.6e-29 100.3 2.8 4.7e-29 100.0 2.0 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Cir_N PF10197.4 CAR28959.1 - 0.022 14.8 6.8 0.037 14.0 4.7 1.4 1 0 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR Striatin PF08232.7 CAR28959.1 - 0.12 12.7 7.9 0.14 12.4 5.5 1.1 1 0 0 1 1 1 0 Striatin family DUF1910 PF08928.5 CAR28959.1 - 0.18 11.8 0.9 0.23 11.5 0.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1910) CT47 PF15623.1 CAR28959.1 - 0.76 9.4 3.9 0.86 9.2 2.7 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 CWC25 PF12542.3 CAR28959.1 - 1.6 9.2 12.2 0.37 11.2 1.7 2.9 1 1 2 3 3 3 0 Pre-mRNA splicing factor tRNA-synt_1e PF01406.14 CAR28960.1 - 1.6e-135 451.0 0.5 3.2e-135 450.0 0.3 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 CAR28960.1 - 1.9e-08 33.3 0.4 5.5e-06 25.2 0.1 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CAR28960.1 - 4.2e-05 21.7 0.0 0.00014 20.0 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) PGAP1 PF07819.8 CAR28961.1 - 1.4e-06 28.0 0.0 3.3e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.10 CAR28961.1 - 1.9e-06 27.1 0.0 3.2e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 CAR28961.1 - 4.1e-05 23.5 0.0 6.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAR28961.1 - 0.00016 21.3 0.0 0.0003 20.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.7 CAR28961.1 - 0.00063 19.1 0.1 0.0011 18.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_8 PF06259.7 CAR28961.1 - 0.0016 17.9 0.0 0.0031 17.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase Ser_hydrolase PF06821.8 CAR28961.1 - 0.0065 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_5 PF12695.2 CAR28961.1 - 0.0091 15.7 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DnaJ PF00226.26 CAR28962.1 - 2.4e-17 62.4 1.3 3.6e-17 61.8 0.9 1.3 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.8 CAR28962.1 - 2.6e-15 55.6 2.9 4.4e-15 54.9 2.0 1.4 1 0 0 1 1 1 1 CSL zinc finger RNA_pol_I_A49 PF06870.7 CAR28963.1 - 1.4e-138 461.7 0.9 1.5e-138 461.5 0.6 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor FGGY_C PF02782.11 CAR28964.1 - 6.6e-23 81.3 0.0 1.1e-22 80.6 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 CAR28964.1 - 1.5e-09 37.5 0.0 2.8e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 CAR28964.1 - 0.00042 19.6 0.0 0.012 14.9 0.0 2.2 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family DUF4445 PF14574.1 CAR28964.1 - 0.026 12.7 0.0 0.17 10.1 0.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4445) AAA_23 PF13476.1 CAR28965.1 - 3e-30 106.0 0.1 3e-30 106.0 0.1 8.3 2 1 2 4 4 2 1 AAA domain Rad50_zn_hook PF04423.9 CAR28965.1 - 1.5e-12 46.8 0.9 1.5e-12 46.8 0.6 5.5 6 0 0 6 6 6 1 Rad50 zinc hook motif SbcCD_C PF13558.1 CAR28965.1 - 5.6e-11 42.2 0.0 1.7e-10 40.6 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 CAR28965.1 - 1.4e-07 31.0 0.1 1.4e-07 31.0 0.0 2.8 2 1 0 2 2 1 1 RecF/RecN/SMC N terminal domain AAA_13 PF13166.1 CAR28965.1 - 3.2e-07 29.2 135.4 2.9e-05 22.7 0.1 7.0 2 1 5 7 7 7 5 AAA domain AAA_21 PF13304.1 CAR28965.1 - 1.7e-06 28.1 16.2 0.00048 20.1 0.0 5.9 3 2 1 5 5 5 2 AAA domain Myosin_tail_1 PF01576.14 CAR28965.1 - 1.1e-05 23.3 66.9 1.1e-05 23.3 46.4 4.9 2 2 0 4 4 4 1 Myosin tail AAA_29 PF13555.1 CAR28965.1 - 0.00044 19.7 0.0 0.0011 18.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.1 CAR28965.1 - 0.058 13.1 0.1 0.15 11.8 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain FTCD_C PF04961.7 CAR28965.1 - 0.37 10.1 6.4 0.63 9.4 1.2 3.5 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase Reo_sigmaC PF04582.7 CAR28965.1 - 0.68 9.0 52.8 0.0078 15.4 3.2 6.8 2 2 5 7 7 7 0 Reovirus sigma C capsid protein FUSC PF04632.7 CAR28965.1 - 1.4 7.2 9.2 0.9 7.8 0.1 3.2 3 0 0 3 3 3 0 Fusaric acid resistance protein family FtsK_SpoIIIE PF01580.13 CAR28965.1 - 2.8 7.3 8.8 0.83 9.0 0.0 3.8 4 0 0 4 4 4 0 FtsK/SpoIIIE family RRM_1 PF00076.17 CAR28966.1 - 5.6e-05 22.7 0.0 9.8e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR28966.1 - 7.4e-05 22.6 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTK3 PF12243.3 CAR28966.1 - 0.02 14.5 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 OS-D PF03392.8 CAR28966.1 - 0.044 13.7 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 Insect pheromone-binding family, A10/OS-D RRM_5 PF13893.1 CAR28966.1 - 0.094 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MRP-L46 PF11788.3 CAR28967.1 - 9.9e-37 126.0 0.9 1.2e-36 125.7 0.1 1.5 2 0 0 2 2 2 1 39S mitochondrial ribosomal protein L46 WD40 PF00400.27 CAR28968.1 - 4.3e-17 61.2 10.3 3.9e-06 26.5 0.0 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CAR28968.1 - 0.0021 16.8 0.4 0.0073 15.0 0.0 1.9 1 1 1 2 2 2 1 Nup133 N terminal like DapH_N PF08503.5 CAR28968.1 - 0.049 13.7 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Tetrahydrodipicolinate succinyltransferase N-terminal RTC4 PF14474.1 CAR28969.1 - 8.6e-39 132.3 0.2 1.4e-38 131.6 0.1 1.3 1 0 0 1 1 1 1 RTC4-like domain zf-CCHC PF00098.18 CAR28970.1 - 2.6e-52 172.3 49.4 1.4e-08 34.2 1.3 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 CAR28970.1 - 1.5e-12 47.0 43.8 0.0044 16.6 0.4 7.1 6 1 1 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 CAR28970.1 - 5.1e-06 26.1 47.9 0.15 11.7 0.8 7.0 2 2 5 7 7 7 6 Zinc knuckle zf-CCHC_6 PF15288.1 CAR28970.1 - 0.042 13.5 2.0 0.042 13.5 1.4 6.8 7 0 0 7 7 7 0 Zinc knuckle zf-CCHC_2 PF13696.1 CAR28970.1 - 0.26 10.8 44.8 0.24 10.9 0.8 7.1 3 3 4 7 7 7 0 Zinc knuckle zf-RING_3 PF14369.1 CAR28970.1 - 1.9 8.5 30.8 0.88 9.6 0.7 5.3 4 2 0 4 4 4 0 zinc-finger Pterin_bind PF00809.17 CAR28971.1 - 1.4e-42 145.4 0.1 1.3e-41 142.3 0.0 2.2 1 1 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 CAR28971.1 - 2.5e-39 133.9 0.1 5.3e-39 132.8 0.1 1.6 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.13 CAR28971.1 - 9.4e-36 122.4 0.1 6e-18 65.0 0.0 2.9 3 0 0 3 3 3 2 Dihydroneopterin aldolase FAD_binding_3 PF01494.14 CAR28972.1 - 8.3e-22 77.7 0.1 5e-15 55.4 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 CAR28972.1 - 8.3e-05 21.6 0.0 0.0022 16.9 0.1 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 CAR28972.1 - 0.00034 20.4 0.0 0.00076 19.2 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding SE PF08491.5 CAR28972.1 - 0.00048 19.0 0.0 0.00076 18.3 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.1 CAR28972.1 - 0.00076 19.4 0.0 0.0017 18.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CAR28972.1 - 0.0014 17.5 0.0 0.0062 15.4 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CAR28972.1 - 0.0021 17.9 0.0 0.0038 17.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 CAR28972.1 - 0.0026 16.4 0.0 0.032 12.8 0.0 2.3 3 0 0 3 3 3 1 Tryptophan halogenase Pyr_redox PF00070.22 CAR28972.1 - 0.0053 17.1 0.0 0.11 12.9 0.0 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CAR28972.1 - 0.021 13.6 0.1 0.03 13.1 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 CAR28972.1 - 0.025 13.0 0.0 0.031 12.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein YGGT PF02325.12 CAR28972.1 - 0.038 13.9 0.2 4.6 7.2 0.0 2.4 2 0 0 2 2 2 0 YGGT family Thi4 PF01946.12 CAR28972.1 - 0.045 12.8 0.0 0.1 11.6 0.0 1.5 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.1 CAR28972.1 - 0.069 13.2 0.0 0.15 12.1 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CAR28972.1 - 0.085 11.7 0.0 0.21 10.4 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pro_isomerase PF00160.16 CAR28973.1 - 5.4e-17 62.4 0.0 7.9e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 CAR28973.1 - 8.2e-15 54.2 0.0 1.7e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR28973.1 - 9e-12 44.8 0.0 2.1e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR28973.1 - 1.1e-09 37.9 0.0 2.4e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF676 PF05057.9 CAR28974.1 - 2.3e-06 27.0 0.0 4.3e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 CAR28974.1 - 8.1e-06 25.5 0.0 1.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF915 PF06028.6 CAR28974.1 - 0.0022 17.1 0.0 0.017 14.1 0.0 2.3 3 0 0 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_5 PF12695.2 CAR28974.1 - 0.029 14.1 0.0 0.089 12.5 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family LCAT PF02450.10 CAR28974.1 - 0.036 13.0 0.0 0.05 12.5 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.15 CAR28974.1 - 0.044 13.3 0.0 0.063 12.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold PH PF00169.24 CAR28975.1 - 2.9e-09 37.0 7.1 2.8e-08 33.8 0.6 3.2 3 0 0 3 3 3 2 PH domain Vps51 PF08700.6 CAR28975.1 - 0.0082 15.9 0.5 0.03 14.1 0.3 2.0 1 0 0 1 1 1 1 Vps51/Vps67 Dsl1_N PF11988.3 CAR28976.1 - 9.9e-141 468.7 10.9 1.9e-140 467.7 7.5 1.4 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 N terminal Dsl1_C PF11989.3 CAR28976.1 - 6.9e-98 327.3 8.8 6.9e-98 327.3 6.1 2.0 3 0 0 3 3 3 1 Retrograde transport protein Dsl1 C terminal Rsc14 PF08586.5 CAR28976.1 - 0.1 13.0 0.8 4.3 7.8 0.1 3.0 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit HMA PF00403.21 CAR28977.1 - 1.6e-10 40.9 0.2 1.9e-10 40.7 0.1 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Yae1_N PF09811.4 CAR28978.1 - 2.1e-08 33.5 4.6 6.3e-08 32.0 3.2 1.9 1 1 0 1 1 1 1 Essential protein Yae1, N terminal GYF PF02213.11 CAR28979.1 - 4.2e-11 42.2 3.0 9.9e-11 41.0 2.1 1.7 1 0 0 1 1 1 1 GYF domain ORC5_C PF14630.1 CAR28980.1 - 1.1e-63 215.2 1.8 1.2e-63 215.1 0.2 1.7 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 CAR28980.1 - 3e-05 24.1 0.0 7.7e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CAR28980.1 - 0.00025 21.1 0.0 0.00051 20.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 CAR28980.1 - 0.0025 17.6 0.0 0.0064 16.3 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NACHT PF05729.7 CAR28980.1 - 0.022 14.3 0.5 0.47 10.0 0.3 2.2 1 1 0 1 1 1 0 NACHT domain Torsin PF06309.6 CAR28980.1 - 0.076 12.9 0.0 0.6 9.9 0.0 2.2 2 0 0 2 2 2 0 Torsin AAA_14 PF13173.1 CAR28980.1 - 0.095 12.6 0.1 0.21 11.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF1744 PF08490.7 CAR28981.1 - 3e-140 467.3 3.2 4.4e-140 466.7 2.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 CAR28981.1 - 2.9e-66 223.5 5.4 3.7e-66 223.2 1.8 2.4 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 CAR28981.1 - 2e-23 82.9 1.5 5e-23 81.6 1.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 CAR28981.1 - 8.1e-07 28.7 0.3 6.2e-06 25.8 0.2 2.3 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB YIF1 PF03878.10 CAR28982.1 - 8.5e-70 234.6 10.1 1.1e-69 234.2 7.0 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 CAR28982.1 - 0.048 13.1 9.7 0.13 11.7 6.7 1.8 1 1 0 1 1 1 0 Yip1 domain DUF202 PF02656.10 CAR28982.1 - 0.14 12.3 3.3 3.2 8.0 0.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF202) VIT1 PF01988.14 CAR28982.1 - 0.66 9.4 3.9 1 8.8 2.7 1.3 1 0 0 1 1 1 0 VIT family DnaJ PF00226.26 CAR28983.1 - 9.9e-16 57.2 0.9 2.7e-15 55.8 0.6 1.8 1 0 0 1 1 1 1 DnaJ domain CRAL_TRIO PF00650.15 CAR28984.1 - 7.8e-38 129.4 0.0 1.1e-37 128.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CAR28984.1 - 7.1e-06 26.0 0.2 1.9e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 CAR28984.1 - 0.067 13.0 0.1 0.16 11.8 0.0 1.6 2 0 0 2 2 2 0 Divergent CRAL/TRIO domain DUF2422 PF10337.4 CAR28985.1 - 1.3e-53 182.4 0.2 1.3e-53 182.4 0.1 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 CAR28985.1 - 2.2e-13 50.2 12.6 2.2e-13 50.2 8.7 2.7 2 2 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 CAR28985.1 - 5e-09 35.3 2.0 2.4e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 Aluminium activated malate transporter DUF2421 PF10334.4 CAR28985.1 - 0.00044 19.9 0.1 0.0013 18.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC PF04632.7 CAR28985.1 - 1.8 6.9 6.2 0.23 9.8 1.4 1.7 2 0 0 2 2 2 0 Fusaric acid resistance protein family UFD1 PF03152.9 CAR28986.1 - 3.9e-72 241.0 0.0 5.1e-72 240.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 TPR_11 PF13414.1 CAR28987.1 - 2.3e-17 62.4 13.6 2.3e-07 30.3 0.0 6.7 6 2 1 8 8 8 3 TPR repeat TPR_16 PF13432.1 CAR28987.1 - 2.9e-12 46.9 8.7 0.031 14.9 0.0 6.3 5 1 2 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.23 CAR28987.1 - 3e-11 42.4 7.1 0.0021 17.5 0.0 7.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_2 PF07719.12 CAR28987.1 - 3.2e-11 42.2 13.4 0.0025 17.5 0.0 8.5 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_12 PF13424.1 CAR28987.1 - 1.1e-10 41.2 12.6 4.2e-06 26.5 0.0 5.9 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 CAR28987.1 - 4.8e-10 39.6 1.6 0.0025 18.0 0.0 4.8 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 CAR28987.1 - 1.9e-09 37.3 0.1 0.42 11.3 0.0 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 CAR28987.1 - 1.5e-08 34.5 2.3 0.17 12.4 0.0 7.6 9 0 0 9 9 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 CAR28987.1 - 1.2e-07 30.9 10.9 0.00012 21.5 0.0 6.8 8 0 0 8 8 8 1 Tetratricopeptide repeat Apc3 PF12895.2 CAR28987.1 - 4.9e-07 29.7 9.9 0.027 14.5 0.2 5.3 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 CAR28987.1 - 1.8e-06 27.6 18.2 0.061 13.5 0.0 8.9 12 0 0 12 12 9 2 Tetratricopeptide repeat TPR_9 PF13371.1 CAR28987.1 - 3.5e-05 23.5 0.1 1.1 9.1 0.0 3.9 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_20 PF14561.1 CAR28987.1 - 0.00053 20.0 1.4 5.2 7.2 0.1 4.4 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 CAR28987.1 - 0.0038 16.9 8.2 0.055 13.2 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPPII_N PF12583.3 CAR28987.1 - 1.3 9.1 5.4 4.3 7.4 0.0 2.7 3 0 0 3 3 2 0 Tripeptidyl peptidase II N terminal TPR_10 PF13374.1 CAR28987.1 - 7.3 6.6 0.0 7.3 6.6 0.0 4.7 7 0 0 7 7 7 0 Tetratricopeptide repeat Ist1 PF03398.9 CAR28988.1 - 2.7e-59 199.2 1.1 3.9e-59 198.7 0.8 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway NOA36 PF06524.7 CAR28988.1 - 0.91 8.7 4.8 1.7 7.8 3.4 1.4 1 0 0 1 1 1 0 NOA36 protein Mmp37 PF09139.6 CAR28989.1 - 7.1e-102 340.8 7.4 1.1e-93 313.9 1.0 2.1 1 1 1 2 2 2 2 Mitochondrial matrix Mmp37 PI3_PI4_kinase PF00454.22 CAR28990.1 - 2.8e-29 102.2 0.2 2.8e-29 102.2 0.1 1.8 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 CAR28990.1 - 2.5e-19 68.7 0.0 7.2e-19 67.2 0.0 1.9 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.15 CAR28990.1 - 1.5e-07 30.8 2.0 3.7e-07 29.4 1.4 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) AA_permease PF00324.16 CAR28991.1 - 3.6e-130 434.5 42.9 4.4e-130 434.2 29.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CAR28991.1 - 1.9e-34 118.9 46.0 2.4e-34 118.6 31.9 1.1 1 0 0 1 1 1 1 Amino acid permease RhodobacterPufX PF11511.3 CAR28991.1 - 0.039 13.3 1.9 1 8.8 0.4 3.0 2 0 0 2 2 2 0 Intrinsic membrane protein PufX AA_permease PF00324.16 CAR28992.1 - 4.3e-135 450.7 47.7 5.4e-135 450.4 33.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CAR28992.1 - 9.1e-27 93.6 51.1 1.2e-26 93.2 35.4 1.2 1 0 0 1 1 1 1 Amino acid permease FH2 PF02181.18 CAR28993.1 - 2.6e-82 276.6 6.9 2.6e-82 276.6 4.8 3.7 3 1 0 3 3 3 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 CAR28993.1 - 5.9e-39 133.5 0.2 5.9e-39 133.5 0.2 4.6 5 0 0 5 5 5 1 Diaphanous FH3 Domain Drf_GBD PF06371.8 CAR28993.1 - 3.3e-28 98.3 7.8 3.3e-28 98.3 5.4 4.5 3 1 1 4 4 4 1 Diaphanous GTPase-binding Domain Sec2p PF06428.6 CAR28994.1 - 1.7e-25 88.7 13.6 1.7e-25 88.7 9.4 3.8 3 0 0 3 3 3 1 GDP/GTP exchange factor Sec2p IFT57 PF10498.4 CAR28994.1 - 0.0028 16.4 12.9 0.0028 16.4 9.0 3.4 2 1 1 3 3 3 1 Intra-flagellar transport protein 57 Aa_trans PF01490.13 CAR28995.1 - 3.4e-78 262.9 31.5 3.9e-78 262.7 21.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TIMELESS PF04821.9 CAR28996.1 - 5.4e-54 183.2 3.3 1.5e-53 181.7 2.3 1.8 1 0 0 1 1 1 1 Timeless protein Peptidase_S8 PF00082.17 CAR28997.1 - 5.1e-22 78.3 2.4 7e-22 77.8 1.7 1.2 1 0 0 1 1 1 1 Subtilase family Cyclin_N PF00134.18 CAR28998.1 - 1.1e-38 131.6 5.6 2.1e-36 124.3 1.2 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 CAR28998.1 - 1.8e-05 24.6 2.6 2.8e-05 24.0 0.1 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain Sad1_UNC PF07738.8 CAR28999.1 - 5.9e-34 116.7 0.0 2.1e-33 115.0 0.0 2.0 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Peptidase_M1 PF01433.15 CAR29000.1 - 3e-11 43.0 0.2 8e-05 21.8 0.0 3.4 2 1 0 2 2 2 2 Peptidase family M1 Oxidored_FMN PF00724.15 CAR29001.1 - 5.9e-65 219.5 0.0 7.1e-65 219.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family 2-Hacid_dh_C PF02826.14 CAR29002.1 - 1e-54 184.3 0.0 2e-54 183.4 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CAR29002.1 - 2.4e-13 49.7 0.0 3.6e-13 49.1 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CAR29002.1 - 4.3e-05 23.4 0.0 8.8e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 CAR29002.1 - 0.039 14.0 0.0 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 CAR29002.1 - 0.046 13.5 1.5 1.1 9.1 0.2 3.0 2 1 1 3 3 3 0 ThiF family IlvN PF07991.7 CAR29002.1 - 0.076 12.3 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain HCO3_cotransp PF00955.16 CAR29004.1 - 1e-60 205.9 13.6 3e-35 121.8 1.4 2.1 1 1 1 2 2 2 2 HCO3- transporter family Per1 PF04080.8 CAR29005.1 - 3.5e-96 321.7 10.6 5.4e-96 321.1 7.4 1.3 1 0 0 1 1 1 1 Per1-like Spindle_Spc25 PF08234.7 CAR29006.1 - 8.1e-19 67.3 0.2 8.1e-19 67.3 0.1 1.7 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Laminin_II PF06009.7 CAR29006.1 - 0.015 15.0 1.2 0.015 15.0 0.9 2.0 1 1 1 2 2 2 0 Laminin Domain II Spc24 PF08286.6 CAR29006.1 - 0.03 14.0 9.0 0.37 10.4 0.4 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Glyco_hydro_63 PF03200.11 CAR29006.1 - 0.059 11.2 1.3 0.064 11.0 0.9 1.2 1 0 0 1 1 1 0 Mannosyl oligosaccharide glucosidase DUF4407 PF14362.1 CAR29006.1 - 0.079 11.9 8.9 0.12 11.3 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF342 PF03961.8 CAR29006.1 - 0.1 11.0 5.1 0.13 10.6 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4300 PF14133.1 CAR29006.1 - 0.12 11.6 1.2 0.11 11.7 0.2 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4300) OmpH PF03938.9 CAR29006.1 - 0.63 9.9 16.4 1.1 9.1 11.4 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Atg14 PF10186.4 CAR29006.1 - 0.67 8.8 20.5 0.95 8.3 14.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HlyD PF00529.15 CAR29006.1 - 2.5 7.3 18.2 3.6 6.8 12.6 1.2 1 0 0 1 1 1 0 HlyD family secretion protein Spc42p PF11544.3 CAR29006.1 - 2.7 7.9 10.5 2 8.3 0.3 3.0 3 0 0 3 3 3 0 Spindle pole body component Spc42p APG6 PF04111.7 CAR29006.1 - 3.8 6.4 12.7 5.7 5.8 8.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 FUSC PF04632.7 CAR29006.1 - 5.7 5.2 8.6 6.9 4.9 6.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exo_endo_phos PF03372.18 CAR29007.1 - 1e-16 61.6 0.1 1.4e-16 61.1 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family 2TM PF13239.1 CAR29007.1 - 0.0069 16.4 1.1 0.015 15.3 0.8 1.5 1 0 0 1 1 1 1 2TM domain Glyco_transf_28 PF03033.15 CAR29008.1 - 9.2e-30 103.2 0.0 2.2e-29 101.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 CAR29008.1 - 3.8e-21 74.3 0.0 1.4e-13 50.0 0.0 2.9 3 0 0 3 3 3 2 GRAM domain PH PF00169.24 CAR29008.1 - 1.1e-10 41.6 0.5 3.7e-10 39.9 0.3 1.9 1 0 0 1 1 1 1 PH domain UDPGT PF00201.13 CAR29008.1 - 5.4e-09 35.1 0.2 4.1e-08 32.2 0.1 2.3 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 CAR29008.1 - 0.0042 16.7 0.0 0.0084 15.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain PH_11 PF15413.1 CAR29008.1 - 0.049 13.8 0.7 0.42 10.8 0.5 2.6 1 1 0 1 1 1 0 Pleckstrin homology domain Abhydrolase_1 PF00561.15 CAR29009.1 - 2.7e-62 210.3 0.0 5.4e-62 209.3 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CAR29009.1 - 5.6e-13 49.3 0.1 6.2e-12 45.8 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CAR29009.1 - 2.3e-06 27.3 0.1 7.5e-05 22.5 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 CAR29009.1 - 0.013 14.9 0.3 0.024 14.0 0.2 1.3 1 0 0 1 1 1 0 Putative esterase ABC_membrane PF00664.18 CAR29010.1 - 4.1e-55 187.1 1.0 5.3e-55 186.7 0.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 CAR29010.1 - 4.7e-31 107.9 0.0 2.5e-30 105.5 0.0 2.1 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 CAR29010.1 - 1.4e-06 27.7 1.9 0.00028 20.1 0.0 2.6 2 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 CAR29010.1 - 1.5e-06 28.9 0.0 3.7e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CAR29010.1 - 1.8e-06 28.1 0.1 4.2e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 CAR29010.1 - 0.00037 20.7 0.0 0.003 17.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CAR29010.1 - 0.0014 18.8 0.1 0.013 15.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.1 CAR29010.1 - 0.0017 18.3 0.0 0.38 10.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CAR29010.1 - 0.0019 17.7 0.0 0.0041 16.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 CAR29010.1 - 0.0023 17.3 0.0 0.022 14.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CAR29010.1 - 0.0023 17.0 0.0 0.0047 16.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin T2SE PF00437.15 CAR29010.1 - 0.0057 15.5 0.0 0.0097 14.8 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_10 PF12846.2 CAR29010.1 - 0.0091 15.4 0.0 0.089 12.2 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain DUF258 PF03193.11 CAR29010.1 - 0.011 14.9 0.2 0.029 13.5 0.0 1.7 2 0 0 2 2 1 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 CAR29010.1 - 0.011 15.1 0.0 0.19 11.1 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein DEAD PF00270.24 CAR29010.1 - 0.013 14.9 0.0 0.14 11.5 0.0 2.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_19 PF13245.1 CAR29010.1 - 0.017 14.8 0.0 0.069 12.9 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain SbcCD_C PF13558.1 CAR29010.1 - 0.023 14.6 0.5 0.11 12.4 0.3 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA PF00004.24 CAR29010.1 - 0.033 14.3 0.0 0.38 10.9 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.12 CAR29010.1 - 0.048 13.4 0.0 0.14 11.9 0.0 1.7 2 0 0 2 2 1 0 Domain of unknown function DUF87 AAA_23 PF13476.1 CAR29010.1 - 0.051 13.8 0.8 0.2 11.9 0.1 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 CAR29010.1 - 0.08 12.9 0.0 0.35 10.9 0.0 2.0 2 0 0 2 2 1 0 Sigma-54 interaction domain ATP-synt_ab PF00006.20 CAR29010.1 - 0.081 12.4 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_ATPase PF09818.4 CAR29010.1 - 0.092 11.3 0.1 0.27 9.7 0.0 1.7 2 0 0 2 2 2 0 Predicted ATPase of the ABC class FtsK_SpoIIIE PF01580.13 CAR29010.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Nup35_RRM_2 PF14605.1 CAR29010.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif PH PF00169.24 CAR29011.1 - 7.9e-08 32.4 0.1 5e-06 26.6 0.0 2.5 2 0 0 2 2 2 1 PH domain PAT1 PF09770.4 CAR29011.1 - 4.7 5.3 19.7 7.2 4.7 13.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 YbaJ PF10757.4 CAR29012.1 - 0.004 17.2 3.3 0.0047 17.0 0.3 2.5 3 0 0 3 3 3 1 Biofilm formation regulator YbaJ Talin_middle PF09141.5 CAR29012.1 - 0.013 15.1 3.2 0.016 14.8 0.4 2.3 2 0 0 2 2 2 0 Talin, middle domain EMG1 PF03587.9 CAR29013.1 - 2.8e-77 258.5 0.0 3.3e-77 258.3 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase LCD1 PF09798.4 CAR29014.1 - 9.2e-183 608.7 33.8 1.1e-182 608.5 23.5 1.1 1 0 0 1 1 1 1 DNA damage checkpoint protein eIF-4B PF06273.6 CAR29014.1 - 1.4 7.6 6.0 2 7.0 4.1 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B DUF342 PF03961.8 CAR29014.1 - 2.1 6.6 7.9 4 5.7 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Ribosomal_L37e PF01907.14 CAR29015.1 - 2.5e-26 91.2 10.8 2.5e-26 91.2 7.5 1.6 2 0 0 2 2 2 1 Ribosomal protein L37e DZR PF12773.2 CAR29015.1 - 0.0013 18.5 1.7 0.0018 18.0 1.2 1.3 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 CAR29015.1 - 0.006 15.7 0.9 0.012 14.8 0.6 1.6 1 1 0 1 1 1 1 zinc-ribbon domain C1_1 PF00130.17 CAR29015.1 - 0.05 13.3 1.7 0.081 12.6 1.2 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_2 PF13240.1 CAR29015.1 - 0.13 11.8 3.6 4.6 6.8 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-C3HC4_3 PF13920.1 CAR29015.1 - 0.16 11.6 2.7 0.23 11.1 1.9 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-NADH-PPase PF09297.6 CAR29015.1 - 0.19 11.2 6.6 4.6 6.8 4.3 2.4 1 1 1 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-C3HC4 PF00097.20 CAR29015.1 - 0.44 10.2 4.6 0.71 9.5 3.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2256 PF10013.4 CAR29015.1 - 2.5 7.9 8.0 1.5 8.6 1.5 2.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_3 PF13878.1 CAR29015.1 - 6.6 6.3 6.5 10 5.8 0.2 2.5 3 0 0 3 3 3 0 zinc-finger of acetyl-transferase ESCO FHA PF00498.21 CAR29016.1 - 5.2e-08 32.8 0.0 2.5e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 FHA domain Ank_5 PF13857.1 CAR29017.1 - 9.9e-15 54.2 1.2 3.5e-06 27.0 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CAR29017.1 - 3.4e-13 49.7 0.0 4.8e-08 33.2 0.0 2.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CAR29017.1 - 1.3e-12 46.6 0.6 0.00014 21.7 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.25 CAR29017.1 - 3.4e-12 45.5 3.6 5e-05 22.8 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CAR29017.1 - 1.9e-09 37.7 0.3 0.0025 18.2 0.0 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) OmpH PF03938.9 CAR29017.1 - 0.0015 18.5 0.8 0.0015 18.5 0.6 2.5 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) ADIP PF11559.3 CAR29017.1 - 0.012 15.5 4.6 0.012 15.5 3.2 3.0 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding CP_ATPgrasp_2 PF14403.1 CAR29017.1 - 0.083 11.5 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Circularly permuted ATP-grasp type 2 FUSC PF04632.7 CAR29017.1 - 3.7 5.8 4.3 0.65 8.3 0.5 1.4 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF605 PF04652.11 CAR29018.1 - 1.1e-49 169.9 14.6 8.9e-35 120.7 1.1 2.0 1 1 1 2 2 2 2 Vta1 like DUF4276 PF14103.1 CAR29018.1 - 0.024 14.5 0.2 0.057 13.2 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4276) S-AdoMet_synt_C PF02773.11 CAR29019.1 - 4.9e-74 246.6 0.2 8.1e-74 245.8 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 CAR29019.1 - 4.9e-45 152.3 0.0 8.8e-45 151.5 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 CAR29019.1 - 3.5e-43 145.9 0.1 7e-43 144.9 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain PAP2 PF01569.16 CAR29020.1 - 1.4e-17 63.5 0.8 1.4e-17 63.5 0.6 1.7 2 0 0 2 2 2 1 PAP2 superfamily BCLP PF12304.3 CAR29020.1 - 6.2e-05 22.5 0.4 0.00074 18.9 0.0 2.2 2 0 0 2 2 2 1 Beta-casein like protein FUSC_2 PF13515.1 CAR29020.1 - 0.014 15.2 0.7 0.014 15.2 0.5 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein-like DUF4149 PF13664.1 CAR29020.1 - 0.69 10.0 0.0 0.69 10.0 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4149) PBP PF01161.15 CAR29021.1 - 7.4e-30 103.7 0.0 9.3e-30 103.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PSP1 PF04468.7 CAR29022.1 - 1.8e-36 123.9 0.0 5.8e-36 122.3 0.0 2.0 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Zip PF02535.17 CAR29022.1 - 1.8 7.5 10.6 0.41 9.6 0.2 3.1 3 0 0 3 3 3 0 ZIP Zinc transporter Cu-oxidase_2 PF07731.9 CAR29023.1 - 6.6e-28 96.9 0.7 6.8e-26 90.4 0.1 3.7 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 CAR29023.1 - 9.3e-23 80.1 4.5 7e-18 64.4 0.4 4.3 5 0 0 5 5 5 3 Multicopper oxidase Cu-oxidase PF00394.17 CAR29023.1 - 2e-17 63.5 0.7 3.1e-14 53.1 0.1 3.6 4 1 0 4 4 4 2 Multicopper oxidase DUF912 PF06024.7 CAR29023.1 - 0.013 15.5 0.0 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3124 PF11322.3 CAR29023.1 - 0.029 14.2 0.2 0.16 11.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3124) Pkinase PF00069.20 CAR29024.1 - 3.9e-71 239.2 0.0 9.4e-71 237.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR29024.1 - 7.5e-32 110.4 0.0 4.3e-31 107.9 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR29024.1 - 0.0014 17.6 0.0 0.0026 16.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CAR29024.1 - 0.11 12.1 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Rad60-SLD PF11976.3 CAR29025.1 - 2.3e-20 72.0 0.1 3e-20 71.6 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CAR29025.1 - 1.3e-12 46.9 0.0 1.6e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family AA_permease PF00324.16 CAR29026.1 - 1.5e-120 402.8 32.2 1.7e-120 402.6 22.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CAR29026.1 - 2.6e-35 121.8 31.6 3.1e-35 121.5 21.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2207 PF09972.4 CAR29026.1 - 0.12 10.9 6.7 0.15 10.6 0.6 2.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Colicin_im PF03857.8 CAR29026.1 - 0.57 9.9 4.3 0.34 10.6 0.8 2.1 2 0 0 2 2 2 0 Colicin immunity protein Nitroreductase PF00881.19 CAR29027.1 - 3.4e-05 23.7 0.0 4.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Nitroreductase family SKG6 PF08693.5 CAR29028.1 - 3.2e-05 23.1 0.0 8.7e-05 21.7 0.0 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain SH3_9 PF14604.1 CAR29028.1 - 0.0064 16.0 0.0 0.017 14.7 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CAR29028.1 - 0.014 14.7 0.0 0.039 13.3 0.0 1.8 1 0 0 1 1 1 0 SH3 domain DUF4448 PF14610.1 CAR29028.1 - 0.039 13.4 0.0 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) CAP PF00188.21 CAR29029.1 - 1.4e-19 70.7 3.2 1.4e-19 70.7 2.3 2.4 2 1 0 2 2 2 1 Cysteine-rich secretory protein family DUF2798 PF11391.3 CAR29029.1 - 7.4 6.4 6.9 15 5.4 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2798) TPR_11 PF13414.1 CAR29030.1 - 0.00042 19.9 0.0 0.00091 18.8 0.0 1.5 1 0 0 1 1 1 1 TPR repeat TPR_16 PF13432.1 CAR29030.1 - 0.0026 18.3 0.0 0.0072 16.9 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.1 CAR29030.1 - 0.0072 16.1 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 CAR29030.1 - 0.012 15.5 0.0 0.034 14.0 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 CAR29030.1 - 0.031 14.9 0.0 0.082 13.5 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.1 CAR29030.1 - 0.041 14.2 0.1 0.097 13.0 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_20 PF14561.1 CAR29030.1 - 0.17 12.0 0.1 0.32 11.1 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat CAP_GLY PF01302.20 CAR29031.1 - 2.7e-16 59.0 0.2 7.2e-16 57.6 0.0 1.8 2 0 0 2 2 2 1 CAP-Gly domain V_ATPase_I PF01496.14 CAR29031.1 - 0.0057 14.5 8.0 0.0075 14.1 5.6 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Allexi_40kDa PF05549.6 CAR29031.1 - 0.059 12.6 6.0 0.032 13.5 2.0 1.8 1 1 0 1 1 1 0 Allexivirus 40kDa protein Nup54 PF13874.1 CAR29031.1 - 0.11 12.2 11.9 0.026 14.1 5.6 1.8 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 zf-CCHC_2 PF13696.1 CAR29031.1 - 0.11 11.9 1.0 0.22 11.0 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF603 PF04645.7 CAR29031.1 - 0.17 11.8 6.5 0.26 11.2 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF603 Angiomotin_C PF12240.3 CAR29031.1 - 0.17 11.3 12.8 0.1 12.1 7.1 1.7 1 1 0 1 1 1 0 Angiomotin C terminal Not1 PF04054.10 CAR29031.1 - 0.17 10.6 1.3 0.23 10.2 0.9 1.1 1 0 0 1 1 1 0 CCR4-Not complex component, Not1 DUF489 PF04356.7 CAR29031.1 - 0.66 9.5 4.4 0.32 10.5 0.5 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF489) Fib_alpha PF08702.5 CAR29031.1 - 1.4 9.0 14.6 1.7 8.7 1.4 2.5 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Med8 PF10232.4 CAR29031.1 - 5.2 6.5 11.3 2.9 7.3 3.8 2.1 1 1 1 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 Histidinol_dh PF00815.15 CAR29032.1 - 6.5e-182 604.7 4.0 9.2e-182 604.2 2.8 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 CAR29032.1 - 1.3e-27 95.2 0.2 3.6e-27 93.8 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 CAR29032.1 - 6.2e-12 45.6 0.2 2e-11 44.0 0.1 2.0 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase Complex1_LYR PF05347.10 CAR29033.1 - 1.9e-10 40.3 0.2 5.3e-10 38.9 0.1 1.8 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CAR29033.1 - 1.8e-08 34.4 0.1 1.8e-08 34.4 0.1 1.8 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 CAR29033.1 - 1.6e-06 28.5 0.3 2.8e-06 27.7 0.2 1.5 1 1 0 1 1 1 1 Complex1_LYR-like RRP7 PF12923.2 CAR29034.1 - 4.9e-33 113.9 7.0 1.1e-32 112.7 4.8 1.6 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_6 PF14259.1 CAR29034.1 - 0.01 15.7 0.3 0.97 9.4 0.0 3.5 4 0 0 4 4 4 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3384 PF11864.3 CAR29034.1 - 0.018 13.5 0.3 0.026 12.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) RRM_1 PF00076.17 CAR29034.1 - 0.041 13.5 2.0 20 4.9 0.0 3.7 4 0 0 4 4 4 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ste50p-SAM PF09235.5 CAR29035.1 - 5.7e-27 93.5 2.3 1.2e-26 92.4 1.6 1.6 1 0 0 1 1 1 1 Ste50p, sterile alpha motif RA PF00788.18 CAR29035.1 - 4.8e-15 55.8 0.0 1e-14 54.7 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_1 PF00536.25 CAR29035.1 - 0.025 14.7 0.1 0.058 13.5 0.1 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF3128 PF11326.3 CAR29036.1 - 1.6e-29 101.8 1.1 1.8e-29 101.6 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) SelR PF01641.13 CAR29037.1 - 7.1e-51 171.0 0.3 8.7e-51 170.8 0.2 1.1 1 0 0 1 1 1 1 SelR domain HECT_2 PF09814.4 CAR29037.1 - 0.042 12.5 1.4 2.2 6.8 0.1 2.0 1 1 0 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DZR PF12773.2 CAR29037.1 - 0.54 10.1 5.3 1.4 8.7 0.3 2.2 1 1 1 2 2 2 0 Double zinc ribbon VHS PF00790.14 CAR29038.1 - 1.2e-06 28.1 0.1 2.4e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 CAR29038.1 - 5e-05 23.2 0.1 0.00028 20.8 0.0 2.0 2 0 0 2 2 2 1 GAT domain EutC PF05985.6 CAR29038.1 - 0.08 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine ammonia-lyase light chain (EutC) Glutaredoxin PF00462.19 CAR29039.1 - 4.1e-13 49.0 0.0 6.5e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_9 PF14595.1 CAR29039.1 - 0.00017 21.1 0.0 0.00022 20.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.1 CAR29039.1 - 0.01 15.6 0.0 0.021 14.6 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin domain Thioredoxin_2 PF13098.1 CAR29039.1 - 0.047 13.8 0.1 0.11 12.7 0.1 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain DUF605 PF04652.11 CAR29040.1 - 0.011 15.1 23.3 0.012 14.9 16.1 1.1 1 0 0 1 1 1 0 Vta1 like RNase_T PF00929.19 CAR29041.1 - 0.04 14.2 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 Exonuclease La PF05383.12 CAR29042.1 - 3.8e-18 65.0 0.0 8.5e-18 63.9 0.0 1.6 1 0 0 1 1 1 1 La domain ATG22 PF11700.3 CAR29043.1 - 1.3e-155 518.5 26.6 1.4e-155 518.4 18.4 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 CAR29043.1 - 1.2e-08 34.0 36.9 6.2e-08 31.7 10.4 3.4 1 1 2 3 3 3 3 Major Facilitator Superfamily WD40 PF00400.27 CAR29044.1 - 2.8e-20 71.3 6.4 7e-05 22.5 0.1 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 CAR29044.1 - 0.0018 18.0 0.1 0.094 12.4 0.0 3.2 4 0 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A Hexokinase_2 PF03727.11 CAR29045.1 - 2e-88 295.6 0.0 2.7e-88 295.3 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 CAR29045.1 - 8.6e-70 234.2 0.0 1.8e-69 233.1 0.0 1.5 2 0 0 2 2 2 1 Hexokinase GRASP55_65 PF04495.9 CAR29046.1 - 4.2e-35 120.7 0.0 4.9e-33 114.0 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain DEC-1_N PF04625.8 CAR29046.1 - 0.019 13.6 9.6 0.028 13.0 6.7 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Thioredoxin PF00085.15 CAR29047.1 - 2.8e-55 184.3 0.4 1.4e-28 98.5 0.0 4.1 4 1 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.1 CAR29047.1 - 1.3e-34 119.5 1.8 2e-23 83.1 0.4 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CAR29047.1 - 9.3e-09 35.1 0.1 0.0088 16.0 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 CAR29047.1 - 2.1e-08 34.3 1.9 0.012 15.8 0.1 3.8 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CAR29047.1 - 8.1e-08 32.2 1.3 0.0075 16.3 0.0 3.8 5 0 0 5 5 5 2 Thioredoxin-like AhpC-TSA PF00578.16 CAR29047.1 - 6.2e-06 25.9 0.0 0.0014 18.2 0.0 2.9 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 CAR29047.1 - 0.00054 19.5 0.0 1.2 8.6 0.0 2.5 2 0 0 2 2 2 2 Redoxin ERp29_N PF07912.8 CAR29047.1 - 0.00069 19.5 0.0 2.2 8.2 0.0 3.3 3 1 0 3 3 3 2 ERp29, N-terminal domain Lipoprotein_11 PF03260.8 CAR29047.1 - 0.039 12.9 0.1 0.076 12.0 0.0 1.4 1 0 0 1 1 1 0 Lepidopteran low molecular weight (30 kD) lipoprotein Thioredoxin_4 PF13462.1 CAR29047.1 - 0.058 13.4 0.2 12 5.9 0.0 2.9 2 0 0 2 2 2 0 Thioredoxin DBINO PF13892.1 CAR29047.1 - 0.064 13.2 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 DNA-binding domain Thioredoxin_9 PF14595.1 CAR29047.1 - 0.065 12.7 1.8 6.4 6.3 0.0 3.0 3 0 0 3 3 3 0 Thioredoxin Mgr1 PF08602.5 CAR29048.1 - 3e-136 454.1 0.6 3.9e-136 453.8 0.4 1.1 1 0 0 1 1 1 1 Mgr1-like, i-AAA protease complex subunit CCDC-167 PF15188.1 CAR29048.1 - 0.038 13.9 0.5 0.076 12.9 0.3 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF1620 PF07774.8 CAR29049.1 - 4.7e-71 238.5 0.1 7.5e-71 237.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 CAR29049.1 - 5.5e-05 22.7 0.0 0.011 15.1 0.0 2.8 2 2 0 2 2 2 2 PQQ-like domain Neisseria_PilC PF05567.6 CAR29049.1 - 0.0029 16.7 0.1 0.0047 16.0 0.0 1.3 1 0 0 1 1 1 1 Neisseria PilC beta-propeller domain FKBP_C PF00254.23 CAR29050.1 - 1.6e-33 114.6 0.0 1.9e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase CTP_transf_2 PF01467.21 CAR29051.1 - 1.2e-05 25.4 0.1 1.7e-05 24.8 0.1 1.6 1 1 0 1 1 1 1 Cytidylyltransferase ATP-sulfurylase PF01747.12 CAR29051.1 - 0.063 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 ATP-sulfurylase Zn_clus PF00172.13 CAR29052.1 - 0.0002 21.1 5.4 0.00036 20.3 3.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Recep_L_domain PF01030.19 CAR29053.1 - 1e-09 38.3 12.7 0.0008 19.3 0.1 5.0 2 2 2 4 4 4 4 Receptor L domain PTPS_related PF10131.4 CAR29053.1 - 0.058 11.5 0.0 0.08 11.0 0.0 1.2 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein LRR_9 PF14580.1 CAR29053.1 - 0.069 12.6 0.4 0.13 11.7 0.3 1.5 1 0 0 1 1 1 0 Leucine-rich repeat Pkinase PF00069.20 CAR29054.1 - 6.4e-65 218.8 0.0 9.3e-65 218.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR29054.1 - 2.1e-45 154.8 0.0 3e-45 154.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR29054.1 - 2.5e-09 36.5 0.0 3.8e-08 32.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like HARP PF07443.8 CAR29054.1 - 0.1 12.0 0.4 7.8 5.9 0.0 2.7 3 0 0 3 3 3 0 HepA-related protein (HARP) ArfGap PF01412.13 CAR29055.1 - 5.7e-30 103.4 5.1 1.4e-29 102.2 3.5 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf QCR10 PF09796.4 CAR29056.1 - 0.01 15.4 2.0 0.025 14.2 1.4 1.7 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Asp_Glu_race PF01177.17 CAR29057.1 - 1.4e-19 70.9 0.0 1.6e-19 70.6 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase RPAP1_C PF08620.5 CAR29058.1 - 3.7e-30 103.5 0.0 8e-30 102.5 0.0 1.6 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 CAR29058.1 - 1.6e-16 59.5 8.2 1.6e-16 59.5 5.7 2.2 3 0 0 3 3 3 1 RPAP1-like, N-terminal HEAT PF02985.17 CAR29058.1 - 0.0033 17.3 0.2 0.071 13.2 0.0 3.1 3 0 0 3 3 3 1 HEAT repeat CTNNBL PF08216.6 CAR29058.1 - 0.007 15.9 0.1 0.019 14.5 0.1 1.7 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear Fumble PF03630.9 CAR29060.1 - 2e-126 421.4 1.4 1.3e-123 412.2 1.0 2.2 1 1 0 1 1 1 1 Fumble ATP_transf PF09830.4 CAR29061.1 - 2.2e-18 65.8 0.0 4.2e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.18 CAR29061.1 - 0.05 14.1 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 HIT domain UCR_14kD PF02271.11 CAR29062.1 - 1.4e-42 143.6 0.1 1.6e-42 143.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Macoilin PF09726.4 CAR29063.1 - 7.7 4.6 22.5 12 3.9 15.6 1.3 1 0 0 1 1 1 0 Transmembrane protein PIG-X PF08320.7 CAR29064.1 - 2.7e-40 137.8 0.0 3.7e-40 137.4 0.0 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 Spb1_C PF07780.7 CAR29065.1 - 1.9e-78 262.8 21.0 1.9e-78 262.8 14.5 3.4 3 0 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.14 CAR29065.1 - 5.6e-52 176.3 0.1 1.5e-51 174.9 0.0 1.8 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.3 CAR29065.1 - 5.9e-52 175.3 12.5 5.9e-52 175.3 8.7 4.6 4 1 0 4 4 4 1 Domain of unknown function (DUF3381) EMP24_GP25L PF01105.19 CAR29065.1 - 9.8 5.8 9.1 0.18 11.5 0.4 2.4 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD MT-A70 PF05063.9 CAR29066.1 - 1.2e-11 44.5 0.0 1.9e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 MT-A70 MSP1_C PF07462.6 CAR29067.1 - 0.56 8.5 7.1 0.073 11.4 1.3 1.9 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus CHAP PF05257.11 CAR29067.1 - 1.4 8.6 4.4 0.85 9.2 0.0 2.7 3 0 0 3 3 3 0 CHAP domain PEX11 PF05648.9 CAR29068.1 - 5.5e-06 25.8 0.9 7.9e-06 25.3 0.6 1.2 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Nucleoside_tran PF01733.13 CAR29068.1 - 0.045 12.9 0.2 0.054 12.6 0.2 1.3 1 0 0 1 1 1 0 Nucleoside transporter Peptidase_M3 PF01432.15 CAR29069.1 - 2.2e-145 485.2 1.3 3.1e-145 484.7 0.9 1.2 1 0 0 1 1 1 1 Peptidase family M3 DUF2250 PF10007.4 CAR29069.1 - 0.053 13.4 1.2 1 9.2 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) DUF543 PF04418.7 CAR29070.1 - 8.5e-31 105.7 0.1 9.7e-31 105.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) SR-25 PF10500.4 CAR29071.1 - 0.62 9.4 14.1 0.91 8.9 9.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pex14_N PF04695.8 CAR29071.1 - 0.94 9.5 5.4 0.39 10.7 2.1 1.5 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region KH_1 PF00013.24 CAR29072.1 - 0.0093 15.5 0.0 0.029 14.0 0.0 1.8 1 1 1 2 2 2 1 KH domain KH_3 PF13014.1 CAR29072.1 - 0.042 13.5 0.0 0.099 12.3 0.0 1.6 1 0 0 1 1 1 0 KH domain DUF4337 PF14235.1 CAR29072.1 - 0.28 10.9 1.9 0.43 10.4 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) MRC1 PF09444.5 CAR29073.1 - 3.4e-42 144.1 18.9 3.4e-42 144.1 13.1 7.2 3 1 5 8 8 8 1 MRC1-like domain PALP PF00291.20 CAR29075.1 - 1.6e-60 204.9 0.0 1.9e-60 204.6 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DAGK_cat PF00781.19 CAR29075.1 - 0.22 10.9 1.1 0.37 10.2 0.1 1.8 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain TFIIA PF03153.8 CAR29076.1 - 0.5 10.1 6.1 0.57 10.0 4.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF601 PF04642.7 CAR29076.1 - 4.5 6.5 6.9 5.9 6.1 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF601 Homeobox PF00046.24 CAR29077.1 - 2e-07 30.4 0.3 4.1e-07 29.5 0.2 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CAR29077.1 - 2.2e-06 27.2 0.2 9.9e-06 25.1 0.1 2.2 2 0 0 2 2 2 1 Homeobox KN domain mRNA_cap_C PF03919.10 CAR29077.1 - 0.018 15.3 0.9 0.65 10.3 0.1 2.3 2 0 0 2 2 2 0 mRNA capping enzyme, C-terminal domain Homez PF11569.3 CAR29077.1 - 0.053 12.5 0.4 0.12 11.4 0.0 1.8 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez MAT_Alpha1 PF04769.7 CAR29078.1 - 9.1e-09 34.9 0.1 1.8e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 GMC_oxred_N PF00732.14 CAR29079.1 - 1.3e-54 185.3 0.0 1.6e-54 185.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CAR29079.1 - 1.8e-31 109.3 0.0 2.8e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 CAR29079.1 - 0.001 17.9 0.2 0.89 8.3 0.5 2.1 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 CAR29079.1 - 0.012 14.5 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 CAR29079.1 - 0.023 14.5 0.0 0.68 9.7 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CAR29079.1 - 0.084 12.9 0.1 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CAR29079.1 - 0.23 10.5 1.0 0.28 10.2 0.1 1.6 2 0 0 2 2 2 0 Thi4 family DAO PF01266.19 CAR29079.1 - 0.4 9.5 1.3 0.64 8.8 0.6 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase Epimerase PF01370.16 CAR29080.1 - 8.3e-22 77.7 0.0 1.4e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CAR29080.1 - 5.6e-13 48.3 0.0 1.5e-11 43.7 0.0 2.4 1 1 1 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 CAR29080.1 - 2.3e-12 46.1 0.0 3.4e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CAR29080.1 - 2.3e-10 40.7 0.0 8e-10 39.0 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 CAR29080.1 - 7.2e-07 28.3 0.0 7.6e-06 25.0 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 CAR29080.1 - 0.00011 22.2 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 CAR29080.1 - 0.00058 19.1 0.0 0.0017 17.6 0.0 1.8 2 1 0 2 2 2 1 NmrA-like family KR PF08659.5 CAR29080.1 - 0.0011 18.6 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 CAR29080.1 - 0.02 13.8 0.0 0.061 12.1 0.0 1.9 1 1 0 1 1 1 0 RmlD substrate binding domain Iron_permease PF04120.7 CAR29081.1 - 1.8e-29 101.9 23.6 7.7e-19 67.6 0.6 4.9 5 0 0 5 5 5 4 Low affinity iron permease DUP PF00674.13 CAR29082.1 - 1.2e-26 92.8 4.3 3e-15 56.0 0.3 2.3 2 0 0 2 2 2 2 DUP family BNR PF02012.15 CAR29083.1 - 7.8e-12 43.1 16.7 0.21 11.5 0.2 8.0 7 0 0 7 7 7 5 BNR/Asp-box repeat PSII_BNR PF14870.1 CAR29083.1 - 5.5e-05 22.2 0.0 0.00056 19.0 0.0 2.6 4 0 0 4 4 4 1 Photosynthesis system II assembly factor YCF48 Mo-co_dimer PF03404.11 CAR29083.1 - 0.00049 19.7 1.6 22 4.6 0.0 5.1 5 1 0 5 5 5 2 Mo-co oxidoreductase dimerisation domain DUP PF00674.13 CAR29084.1 - 2e-07 30.9 1.4 2e-07 30.9 1.0 2.3 2 0 0 2 2 2 1 DUP family SMP_2 PF10144.4 CAR29084.1 - 0.18 10.9 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin Herpes_UL73 PF03554.8 CAR29084.1 - 0.74 9.6 5.9 3.1 7.6 0.8 2.5 2 0 0 2 2 2 0 UL73 viral envelope glycoprotein YrhK PF14145.1 CAR29085.1 - 0.56 9.9 6.1 0.26 10.9 0.7 2.4 2 1 0 2 2 2 0 YrhK-like protein HD PF01966.17 CAR29086.1 - 1.5e-07 31.4 0.0 2.7e-07 30.6 0.0 1.4 1 1 0 1 1 1 1 HD domain UbiD PF01977.11 CAR29087.1 - 0.063 11.7 0.0 0.067 11.6 0.0 1.0 1 0 0 1 1 1 0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Epimerase PF01370.16 CAR29088.1 - 1.6e-23 83.4 0.0 2.3e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CAR29088.1 - 7.7e-15 54.4 0.0 2e-13 49.8 0.0 2.6 1 1 1 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 CAR29088.1 - 1.2e-13 50.4 0.0 1.6e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CAR29088.1 - 4.6e-12 46.3 0.0 1.5e-11 44.6 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 CAR29088.1 - 7e-07 28.4 0.0 4.6e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.8 CAR29088.1 - 0.00023 20.4 0.1 0.00088 18.5 0.1 1.9 2 1 0 2 2 2 1 NmrA-like family adh_short PF00106.20 CAR29088.1 - 0.00072 19.5 0.0 0.0023 17.8 0.0 1.9 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CAR29088.1 - 0.0054 16.4 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 CAR29088.1 - 0.029 13.2 0.0 0.055 12.3 0.0 1.6 1 1 0 1 1 1 0 RmlD substrate binding domain Sugar_tr PF00083.19 CAR29089.1 - 2.2e-164 547.3 34.6 2.5e-164 547.1 24.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR29089.1 - 2.9e-27 95.2 32.5 5e-27 94.5 15.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 CAR29090.1 - 1.5e-19 69.9 1.5 2.8e-19 68.9 1.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR29090.1 - 0.00014 21.6 11.9 0.0003 20.6 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hydantoinase_B PF02538.9 CAR29091.1 - 2.7e-219 728.7 0.2 3.5e-219 728.3 0.2 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 CAR29091.1 - 1.9e-88 296.3 0.0 4e-88 295.2 0.0 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 CAR29091.1 - 1.4e-54 184.2 0.1 2.3e-52 177.0 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region DUF615 PF04751.9 CAR29091.1 - 0.02 14.5 0.3 0.04 13.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF615) MFS_1 PF07690.11 CAR29092.1 - 1.5e-40 139.0 20.4 1.8e-40 138.7 14.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2427 PF10348.4 CAR29092.1 - 1.2 8.7 5.4 3.5 7.2 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) Fungal_trans_2 PF11951.3 CAR29093.1 - 3.6e-46 157.5 6.6 4.8e-46 157.0 4.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR29093.1 - 7.5e-08 32.1 11.0 1.7e-07 31.0 7.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_4 PF01063.14 CAR29094.1 - 2.7e-29 102.3 0.0 3.4e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV 5-FTHF_cyc-lig PF01812.15 CAR29095.1 - 8e-41 139.8 0.0 9.2e-41 139.6 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family SET PF00856.23 CAR29097.1 - 4.8e-14 52.9 0.0 1.5e-13 51.3 0.0 1.9 2 1 0 2 2 2 1 SET domain HSF_DNA-bind PF00447.12 CAR29098.1 - 4.3e-34 116.7 1.8 9.7e-34 115.6 1.2 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 CAR29098.1 - 8.7e-26 90.1 0.4 2.3e-25 88.7 0.3 1.8 1 0 0 1 1 1 1 Response regulator receiver domain Pkinase PF00069.20 CAR29099.1 - 4.2e-69 232.5 0.0 8.7e-69 231.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR29099.1 - 2.9e-31 108.4 0.0 4.8e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 CAR29099.1 - 4.4e-10 39.9 2.1 4.4e-10 39.9 1.4 2.6 2 1 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 CAR29099.1 - 2e-09 36.8 0.0 3.7e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like C2 PF00168.25 CAR29099.1 - 5.5e-08 32.5 0.0 6e-07 29.2 0.0 2.4 1 1 0 1 1 1 1 C2 domain YrbL-PhoP_reg PF10707.4 CAR29099.1 - 0.017 14.4 0.0 0.045 13.0 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL FAM131 PF15010.1 CAR29099.1 - 0.04 13.6 8.3 0.025 14.3 4.0 1.8 1 1 1 2 2 2 0 Putative cell signalling Glyco_hydro_47 PF01532.15 CAR29100.1 - 1.2e-123 413.1 0.1 1.6e-123 412.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF2593 PF10767.4 CAR29100.1 - 0.14 11.8 0.1 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2593) Ribosomal_S4e PF00900.15 CAR29101.1 - 1.5e-32 111.0 1.0 1.3e-31 108.0 0.4 2.1 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.7 CAR29101.1 - 1.5e-19 69.5 5.4 3.2e-19 68.4 3.7 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 CAR29101.1 - 3.6e-09 35.9 0.4 8.1e-09 34.7 0.0 1.8 2 0 0 2 2 2 1 S4 domain KOW PF00467.24 CAR29101.1 - 1.5e-05 24.5 1.7 1.5e-05 24.5 1.2 3.5 4 0 0 4 4 4 1 KOW motif Metallophos PF00149.23 CAR29102.1 - 4.1e-10 39.3 3.1 6.8e-10 38.6 2.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase KaiA PF07688.7 CAR29102.1 - 0.0075 15.5 0.1 7.7 5.7 0.0 3.1 2 1 1 3 3 3 3 KaiA domain DSPn PF14671.1 CAR29103.1 - 1.7e-50 170.7 0.0 4.5e-50 169.2 0.0 1.7 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 CAR29103.1 - 4.1e-24 84.6 0.0 4.9e-23 81.1 0.0 2.2 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CAR29103.1 - 4.5e-05 22.9 0.0 9.6e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 CAR29103.1 - 0.0007 19.0 0.1 0.0014 18.1 0.1 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 CAR29103.1 - 0.061 13.3 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 CAR29103.1 - 0.38 10.9 0.1 0.38 10.9 0.1 2.4 3 0 0 3 3 3 0 Tyrosine phosphatase family Acetyltransf_13 PF13880.1 CAR29104.1 - 6.5e-22 77.0 0.1 1.9e-21 75.5 0.1 1.8 2 0 0 2 2 2 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 CAR29104.1 - 3.4e-13 48.9 0.4 5.7e-13 48.2 0.3 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Zn_ribbon_recom PF13408.1 CAR29104.1 - 0.0049 17.0 0.6 1.4 9.2 0.3 2.7 2 1 0 2 2 2 2 Recombinase zinc beta ribbon domain Acetyltransf_1 PF00583.19 CAR29104.1 - 0.021 14.8 0.0 0.058 13.4 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CAR29104.1 - 0.033 14.3 0.0 0.062 13.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-met PF12874.2 CAR29104.1 - 1.1 9.5 5.0 5 7.4 0.9 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type PHP PF02811.14 CAR29105.1 - 8.8e-21 74.4 0.1 1.8e-20 73.4 0.1 1.5 1 1 0 1 1 1 1 PHP domain ProRS-C_1 PF09180.6 CAR29106.1 - 2.9e-25 87.9 1.2 5.6e-25 87.0 0.8 1.5 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 CAR29106.1 - 8e-22 77.6 0.0 1.5e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CAR29106.1 - 8.1e-19 67.3 0.0 1.7e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_edit PF04073.10 CAR29106.1 - 0.0054 16.5 0.1 0.011 15.5 0.1 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain tRNA-synt_2 PF00152.15 CAR29107.1 - 4.2e-73 246.0 0.0 9.2e-73 244.9 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CAR29107.1 - 5.4e-13 48.5 0.0 1.1e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Ins134_P3_kin PF05770.6 CAR29107.1 - 0.059 12.3 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Inositol 1, 3, 4-trisphosphate 5/6-kinase Ish1 PF10281.4 CAR29107.1 - 0.065 13.3 1.8 0.077 13.0 0.1 2.1 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Lyase_1 PF00206.15 CAR29108.1 - 1e-96 323.8 0.0 1.6e-96 323.1 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 CAR29108.1 - 4.1e-25 87.6 0.0 8.6e-25 86.6 0.0 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DUF1776 PF08643.5 CAR29109.1 - 1.1e-46 159.3 0.2 1.8e-46 158.6 0.2 1.4 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DUF500 PF04366.7 CAR29110.1 - 2e-47 159.7 0.2 3.4e-47 158.9 0.2 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 CAR29110.1 - 3.6e-15 55.0 0.1 6.9e-15 54.1 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CAR29110.1 - 1.7e-13 49.9 0.2 3.8e-13 48.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CAR29110.1 - 8.9e-12 44.3 0.1 8.9e-12 44.3 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain RRM_1 PF00076.17 CAR29111.1 - 1.2e-42 143.3 6.3 1.1e-14 53.7 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR29111.1 - 4.8e-27 93.7 0.3 1.6e-08 34.4 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR29111.1 - 1.1e-20 73.1 3.4 1e-06 28.4 0.4 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CAR29111.1 - 0.0053 16.4 0.1 0.3 10.8 0.0 2.9 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Pyr_redox_2 PF07992.9 CAR29112.1 - 5.2e-21 75.4 0.0 1.2e-20 74.3 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CAR29112.1 - 2e-15 56.9 0.2 2e-11 44.0 0.0 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CAR29112.1 - 0.046 13.7 0.0 8.2 6.4 0.0 3.0 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Rhodanese PF00581.15 CAR29112.1 - 0.095 13.0 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Rhodanese-like domain YjcQ PF09639.5 CAR29112.1 - 0.11 12.6 0.1 0.36 10.9 0.1 1.8 1 0 0 1 1 1 0 YjcQ protein NAP PF00956.13 CAR29113.1 - 2.6e-12 46.3 1.8 3.1e-06 26.4 0.2 2.1 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) Arrestin_C PF02752.17 CAR29114.1 - 6.3e-22 78.1 0.3 4.5e-21 75.3 0.0 2.6 3 1 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CAR29114.1 - 3.4e-11 43.1 0.0 3e-07 30.3 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 CAR29114.1 - 0.0041 16.6 0.0 0.0097 15.4 0.0 1.6 1 0 0 1 1 1 1 Arrestin_N terminal like WD40 PF00400.27 CAR29115.1 - 9.4e-08 31.6 0.0 0.0037 17.0 0.0 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat PIP5K PF01504.13 CAR29116.1 - 7.9e-65 218.4 4.6 2.1e-64 217.0 1.1 3.0 3 0 0 3 3 3 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 CAR29116.1 - 2.4e-26 92.4 0.1 3.8e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 CAR29116.1 - 2e-17 62.8 10.8 2e-17 62.8 7.5 1.8 2 0 0 2 2 2 1 FYVE zinc finger IBR PF01485.16 CAR29116.1 - 0.71 9.7 7.9 0.25 11.2 3.0 2.1 2 0 0 2 2 2 0 IBR domain DZR PF12773.2 CAR29116.1 - 0.9 9.4 10.5 49 3.8 0.0 3.3 2 1 0 2 2 2 0 Double zinc ribbon Peptidase_M28 PF04389.12 CAR29117.1 - 4.6e-39 134.0 0.0 6e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 RibD_C PF01872.12 CAR29117.1 - 0.062 12.8 0.0 0.14 11.7 0.0 1.5 2 0 0 2 2 2 0 RibD C-terminal domain TIP120 PF08623.5 CAR29118.1 - 0.00034 20.2 0.0 0.0042 16.6 0.0 2.4 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) PTRF_SDPR PF15237.1 CAR29118.1 - 0.0067 15.8 0.1 0.011 15.1 0.1 1.3 1 0 0 1 1 1 1 PTRF/SDPR family IL3 PF02059.10 CAR29118.1 - 0.021 14.8 0.6 11 6.0 0.0 2.9 2 0 0 2 2 2 0 Interleukin-3 GTP_EFTU PF00009.22 CAR29120.1 - 1.5e-35 122.3 8.3 5.4e-33 114.0 3.7 3.0 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain IF-2 PF11987.3 CAR29120.1 - 3.6e-25 87.9 0.4 9.6e-25 86.5 0.3 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 CAR29120.1 - 2.4e-10 40.3 3.5 9.6e-05 22.4 0.1 3.3 3 0 0 3 3 3 2 Elongation factor Tu domain 2 IF2_N PF04760.10 CAR29120.1 - 1.4e-08 34.2 0.0 5.4e-08 32.3 0.0 2.1 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.18 CAR29120.1 - 4.9e-07 29.7 1.6 1.3e-06 28.3 0.4 2.3 3 0 0 3 3 3 1 50S ribosome-binding GTPase Miro PF08477.8 CAR29120.1 - 3.4e-06 27.5 1.4 2.6e-05 24.7 0.4 2.4 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 CAR29120.1 - 0.0003 20.6 1.5 0.52 10.1 0.1 3.4 2 1 1 3 3 3 2 Dynamin family SRPRB PF09439.5 CAR29120.1 - 0.00085 18.5 0.1 0.0018 17.5 0.1 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CAR29120.1 - 0.0035 16.7 0.1 0.0069 15.7 0.1 1.5 1 0 0 1 1 1 1 Ras family PduV-EutP PF10662.4 CAR29120.1 - 0.014 14.8 1.3 0.062 12.7 0.9 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 CAR29120.1 - 0.018 14.3 1.5 0.065 12.5 0.3 2.6 2 1 0 2 2 2 0 Ferrous iron transport protein B PDCD2_C PF04194.8 CAR29121.1 - 1.3e-39 135.4 5.3 3.1e-39 134.2 0.0 3.0 2 1 1 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain ABC_tran PF00005.22 CAR29122.1 - 3.4e-46 156.9 1.4 8.9e-22 77.8 0.2 3.2 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 CAR29122.1 - 9.4e-22 78.3 10.1 1.8e-08 34.7 0.3 5.0 3 2 0 4 4 4 3 AAA domain ABC_tran_2 PF12848.2 CAR29122.1 - 5.9e-19 67.6 8.8 5.9e-19 67.6 6.1 3.0 4 0 0 4 4 1 1 ABC transporter SMC_N PF02463.14 CAR29122.1 - 8e-11 41.5 0.1 0.00079 18.7 0.1 3.7 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 CAR29122.1 - 5.9e-10 38.7 10.3 0.01 14.8 0.4 5.1 4 1 1 5 5 5 3 AAA ATPase domain AAA_17 PF13207.1 CAR29122.1 - 3.2e-08 34.4 2.9 0.00073 20.3 0.0 3.5 5 0 0 5 5 2 2 AAA domain AAA_29 PF13555.1 CAR29122.1 - 1.7e-07 30.6 0.2 0.026 14.0 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.1 CAR29122.1 - 1e-06 28.8 0.0 0.036 14.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 CAR29122.1 - 1.8e-06 28.4 0.1 0.047 14.1 0.0 2.9 2 1 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 CAR29122.1 - 2.4e-06 27.6 1.4 0.01 15.8 0.1 3.0 3 0 0 3 3 2 2 AAA ATPase domain NACHT PF05729.7 CAR29122.1 - 3.5e-06 26.7 0.3 0.022 14.4 0.1 2.6 2 0 0 2 2 2 2 NACHT domain DUF258 PF03193.11 CAR29122.1 - 5.6e-06 25.6 0.0 0.021 14.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 CAR29122.1 - 8.3e-06 25.9 0.9 0.25 11.5 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_14 PF13173.1 CAR29122.1 - 1e-05 25.4 0.3 0.34 10.8 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA_33 PF13671.1 CAR29122.1 - 3.3e-05 23.7 0.7 0.097 12.5 0.0 3.2 3 1 0 3 3 2 2 AAA domain ATP-synt_ab PF00006.20 CAR29122.1 - 3.5e-05 23.3 0.0 0.0088 15.5 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.24 CAR29122.1 - 3.6e-05 23.9 0.4 0.19 11.9 0.0 3.6 4 1 0 4 4 2 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 CAR29122.1 - 7.5e-05 22.2 0.4 0.25 10.7 0.1 2.8 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 CAR29122.1 - 9.8e-05 22.4 0.8 0.75 9.9 0.0 3.7 4 0 0 4 4 3 1 RNA helicase MobB PF03205.9 CAR29122.1 - 0.00013 21.6 0.1 0.25 11.0 0.1 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 CAR29122.1 - 0.00029 21.1 9.7 0.11 12.7 0.3 4.5 5 2 1 6 6 4 2 AAA domain NB-ARC PF00931.17 CAR29122.1 - 0.00033 19.6 0.1 0.37 9.6 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_25 PF13481.1 CAR29122.1 - 0.00037 19.9 0.1 0.45 9.8 0.1 3.0 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 CAR29122.1 - 0.0004 20.3 0.0 0.16 11.9 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_5 PF07728.9 CAR29122.1 - 0.00068 19.3 1.7 3.6 7.3 0.0 3.6 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 CAR29122.1 - 0.001 18.9 0.1 2.3 8.2 0.0 3.4 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Pox_A32 PF04665.7 CAR29122.1 - 0.0023 17.2 0.2 0.17 11.1 0.0 2.5 2 0 0 2 2 2 1 Poxvirus A32 protein AAA_23 PF13476.1 CAR29122.1 - 0.0029 17.9 32.9 0.11 12.7 0.0 5.3 5 1 0 5 5 4 2 AAA domain ArgK PF03308.11 CAR29122.1 - 0.004 15.9 0.0 0.25 10.0 0.0 2.6 2 0 0 2 2 2 1 ArgK protein AAA_10 PF12846.2 CAR29122.1 - 0.0047 16.4 3.6 2.1 7.6 0.3 3.8 4 2 1 5 5 5 1 AAA-like domain AAA_24 PF13479.1 CAR29122.1 - 0.0062 16.1 0.1 5.3 6.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 CAR29122.1 - 0.0075 15.3 0.4 1.1 8.2 0.0 2.6 2 0 0 2 2 2 1 Septin T2SE PF00437.15 CAR29122.1 - 0.0081 15.0 0.0 0.39 9.5 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein NTPase_1 PF03266.10 CAR29122.1 - 0.0087 15.7 0.0 3.3 7.3 0.0 2.6 2 0 0 2 2 2 1 NTPase cobW PF02492.14 CAR29122.1 - 0.012 15.0 0.0 3.3 7.1 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.13 CAR29122.1 - 0.017 14.4 0.0 5.4 6.2 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_19 PF13245.1 CAR29122.1 - 0.025 14.3 0.0 4.8 7.0 0.0 3.6 4 0 0 4 4 3 0 Part of AAA domain Mg_chelatase PF01078.16 CAR29122.1 - 0.038 13.1 0.4 3.7 6.6 0.0 2.9 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI SRP54 PF00448.17 CAR29122.1 - 0.042 13.2 0.2 2.5 7.5 0.1 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Dynamin_N PF00350.18 CAR29122.1 - 0.089 12.6 9.4 0.061 13.1 0.3 3.6 3 1 1 4 4 3 0 Dynamin family Ras PF00071.17 CAR29122.1 - 0.1 11.9 1.3 15 4.9 0.0 3.0 3 0 0 3 3 3 0 Ras family FtsK_SpoIIIE PF01580.13 CAR29122.1 - 0.18 11.2 1.2 5.7 6.3 0.0 3.1 4 0 0 4 4 4 0 FtsK/SpoIIIE family DUF2813 PF11398.3 CAR29122.1 - 8.6 5.3 11.4 1.3 8.0 0.1 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF2813) RNB PF00773.14 CAR29123.1 - 5.9e-93 311.6 0.0 9.5e-93 311.0 0.0 1.3 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 CAR29123.1 - 1.8e-13 50.7 0.2 4.7e-13 49.4 0.2 1.7 1 0 0 1 1 1 1 PIN domain OB_RNB PF08206.6 CAR29123.1 - 0.016 14.6 0.0 0.057 12.9 0.0 1.9 1 0 0 1 1 1 0 Ribonuclease B OB domain PIN PF01850.16 CAR29123.1 - 0.056 13.7 0.1 0.19 12.0 0.1 2.0 1 0 0 1 1 1 0 PIN domain UCH PF00443.24 CAR29124.1 - 1.1e-52 178.8 6.0 1.3e-52 178.5 4.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CAR29124.1 - 2.7e-18 66.4 16.1 5.4e-18 65.4 11.1 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 CAR29124.1 - 0.00068 18.9 0.0 0.004 16.5 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin family SPDY PF03771.11 CAR29124.1 - 0.052 13.0 0.1 0.097 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF317) DUF1690 PF07956.6 CAR29125.1 - 7.6e-43 145.8 11.6 8.6e-43 145.7 8.0 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) DUF4240 PF14024.1 CAR29125.1 - 0.11 12.3 1.2 0.17 11.7 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4240) Pneumo_phosprot PF02478.11 CAR29125.1 - 0.11 12.0 7.5 0.15 11.5 5.2 1.1 1 0 0 1 1 1 0 Pneumovirus phosphoprotein ARD PF03079.9 CAR29126.1 - 1.4e-41 142.0 0.2 1.6e-41 141.8 0.1 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 CAR29126.1 - 1.7e-08 33.8 0.0 2.6e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 CAR29126.1 - 3.8e-05 23.3 0.0 6.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 CAR29126.1 - 0.034 13.5 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 Cupin PQ-loop PF04193.9 CAR29127.1 - 1.7e-13 49.9 9.6 1.3e-10 40.6 3.3 3.1 2 0 0 2 2 2 2 PQ loop repeat Reovirus_M2 PF05993.7 CAR29127.1 - 0.084 10.6 2.8 0.11 10.3 1.9 1.1 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) Pet127 PF08634.5 CAR29128.1 - 1.2e-104 349.3 8.1 3.5e-103 344.5 5.6 2.3 1 1 0 1 1 1 1 Mitochondrial protein Pet127 TauD PF02668.11 CAR29129.1 - 9.3e-55 186.0 0.1 1.4e-54 185.5 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Ribonuc_red_lgC PF02867.10 CAR29129.1 - 0.066 11.7 0.0 0.095 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribonucleotide reductase, barrel domain TP6A_N PF04406.9 CAR29130.1 - 5.1e-13 48.4 0.7 1.8e-12 46.7 0.5 2.0 1 0 0 1 1 1 1 Type IIB DNA topoisomerase EMP24_GP25L PF01105.19 CAR29131.1 - 2.2e-36 125.2 0.0 2.6e-36 125.0 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD FUN14 PF04930.10 CAR29132.1 - 0.00036 20.7 3.5 0.00036 20.7 2.4 1.9 2 1 0 2 2 2 1 FUN14 family DUF4589 PF15252.1 CAR29132.1 - 0.16 11.7 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) B56 PF01603.15 CAR29133.1 - 1.6e-147 491.4 17.1 7.7e-140 466.1 8.1 2.1 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) Acetyltransf_7 PF13508.1 CAR29134.1 - 0.096 12.8 0.1 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AA_permease_2 PF13520.1 CAR29135.1 - 4.6e-70 236.2 43.3 5.9e-70 235.9 30.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CAR29135.1 - 1.3e-24 86.4 34.6 2e-24 85.8 24.0 1.3 1 0 0 1 1 1 1 Amino acid permease DUF3185 PF11381.3 CAR29135.1 - 0.18 11.6 8.1 0.33 10.7 2.8 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) Spo7 PF03907.8 CAR29136.1 - 1.2e-87 292.8 7.3 1.5e-87 292.6 5.0 1.1 1 0 0 1 1 1 1 Spo7-like protein DUF2207 PF09972.4 CAR29136.1 - 0.041 12.4 0.6 0.049 12.2 0.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3722 PF12519.3 CAR29137.1 - 1.9e-79 266.5 11.5 4.3e-79 265.4 8.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Ycf1 PF05758.7 CAR29138.1 - 6.8 4.2 38.4 0.45 8.1 14.5 2.3 2 0 0 2 2 2 0 Ycf1 SMC_N PF02463.14 CAR29139.1 - 3.3e-14 52.6 47.5 2.4e-13 49.8 32.9 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CAR29139.1 - 4.9e-14 53.1 39.9 4.9e-14 53.1 27.7 5.9 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.1 CAR29139.1 - 2.3e-05 23.8 0.0 4.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 CAR29139.1 - 0.00096 18.4 0.3 0.00096 18.4 0.2 4.5 2 2 3 6 6 6 2 Reovirus sigma C capsid protein AAA_25 PF13481.1 CAR29139.1 - 0.0031 16.9 0.1 0.014 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain MutS_V PF00488.16 CAR29139.1 - 0.013 14.9 0.0 0.036 13.4 0.0 1.7 1 0 0 1 1 1 0 MutS domain V FtsK_SpoIIIE PF01580.13 CAR29139.1 - 0.018 14.5 2.9 0.47 9.8 0.0 3.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_33 PF13671.1 CAR29139.1 - 0.059 13.2 1.0 0.48 10.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 CAR29139.1 - 6.1 6.7 32.5 0.02 14.8 7.2 4.8 2 1 1 4 4 4 0 AAA domain UCH PF00443.24 CAR29140.1 - 3.6e-61 206.6 0.0 1.1e-60 205.0 0.0 1.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 CAR29140.1 - 4.2e-47 157.3 4.8 5e-22 77.0 0.1 5.0 5 0 0 5 5 5 4 A repeated domain in UCH-protein UCH_1 PF13423.1 CAR29140.1 - 2.5e-10 40.2 0.8 0.00042 19.8 0.5 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase EF-hand_7 PF13499.1 CAR29141.1 - 1.3e-26 92.5 15.0 1.7e-13 50.4 1.5 3.4 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 CAR29141.1 - 4.8e-26 88.0 4.5 1.7e-07 30.0 0.1 4.5 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 CAR29141.1 - 8.7e-24 81.2 1.8 1.6e-06 27.4 0.0 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 CAR29141.1 - 5.1e-19 66.6 7.9 1.3e-05 24.2 0.1 4.7 5 1 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 CAR29141.1 - 9.3e-19 66.7 4.3 1.3e-08 34.2 0.0 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.1 CAR29141.1 - 0.00013 21.7 0.2 0.0023 17.7 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.2 CAR29141.1 - 0.00033 20.3 4.4 0.99 9.1 0.1 3.4 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CAR29141.1 - 0.0013 18.7 0.6 0.05 13.6 0.3 2.9 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region S10_plectin PF03501.10 CAR29141.1 - 0.0032 17.3 0.0 0.0053 16.5 0.0 1.5 1 0 0 1 1 1 1 Plectin/S10 domain EF-hand_10 PF14788.1 CAR29141.1 - 0.017 14.8 0.2 2.5 7.8 0.0 3.0 3 0 0 3 3 3 0 EF hand COQ7 PF03232.8 CAR29142.1 - 5.7e-74 247.2 0.1 6.9e-74 247.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 CAR29142.1 - 0.042 14.1 0.1 0.12 12.6 0.0 1.8 2 1 0 2 2 2 0 Rubrerythrin YTH PF04146.10 CAR29143.1 - 1.7e-39 134.5 0.1 2.5e-39 134.0 0.1 1.2 1 0 0 1 1 1 1 YT521-B-like domain AAA_32 PF13654.1 CAR29144.1 - 0.12 11.0 0.0 0.13 10.8 0.0 1.0 1 0 0 1 1 1 0 AAA domain BCS1_N PF08740.6 CAR29145.1 - 9.4e-50 168.8 0.1 1.7e-49 168.0 0.0 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 CAR29145.1 - 5.3e-23 81.6 0.0 9.9e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CAR29145.1 - 1.3e-05 25.9 0.0 2.7e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CAR29145.1 - 0.0013 18.5 0.0 0.003 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CAR29145.1 - 0.0019 18.2 0.0 0.0042 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CAR29145.1 - 0.0021 18.2 0.0 0.0056 16.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CAR29145.1 - 0.0022 18.3 0.0 0.012 15.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 CAR29145.1 - 0.0029 17.5 0.1 0.0058 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CAR29145.1 - 0.004 16.2 0.0 0.0068 15.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 CAR29145.1 - 0.0042 16.5 0.0 0.0072 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CAR29145.1 - 0.006 16.4 0.0 0.021 14.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CAR29145.1 - 0.0074 15.4 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_5 PF07728.9 CAR29145.1 - 0.0092 15.7 0.0 0.021 14.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 CAR29145.1 - 0.019 15.2 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 CAR29145.1 - 0.02 14.4 0.0 0.059 12.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.1 CAR29145.1 - 0.021 14.4 0.1 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 CAR29145.1 - 0.022 13.6 0.0 0.034 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.7 CAR29145.1 - 0.029 14.0 0.0 0.26 10.9 0.0 2.5 2 1 1 3 3 3 0 NACHT domain RNA_helicase PF00910.17 CAR29145.1 - 0.039 14.1 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 CAR29145.1 - 0.051 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Arch_ATPase PF01637.13 CAR29145.1 - 0.056 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase KaiC PF06745.8 CAR29145.1 - 0.06 12.4 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.1 CAR29145.1 - 0.065 13.5 0.0 0.24 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 CAR29145.1 - 0.11 12.9 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AAA_28 PF13521.1 CAR29145.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 CAR29145.1 - 0.13 10.9 0.0 1.1 7.8 0.0 2.0 2 0 0 2 2 2 0 TIP49 C-terminus DUF3315 PF11776.3 CAR29145.1 - 0.23 10.9 0.1 0.23 10.9 0.1 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF3315) Lipase_GDSL_2 PF13472.1 CAR29146.1 - 1.3e-19 71.0 0.0 1.5e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 CAR29146.1 - 4.2e-19 69.2 0.0 5.1e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Pyr_redox_3 PF13738.1 CAR29147.1 - 4.3e-05 23.6 0.0 0.034 14.1 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CAR29147.1 - 0.00074 19.4 0.0 0.0017 18.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 CAR29147.1 - 0.0031 17.2 0.0 0.015 15.1 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CAR29147.1 - 0.0053 16.6 0.0 0.046 13.5 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase F1F0-ATPsyn_F PF10791.4 CAR29148.1 - 6.8e-44 148.0 0.2 7.6e-44 147.8 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 CAR29148.1 - 0.11 12.6 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f LSM PF01423.17 CAR29149.1 - 1.9e-15 56.1 0.0 2.5e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CAR29149.1 - 1e-05 25.3 0.0 0.00017 21.4 0.0 2.1 1 1 1 2 2 2 1 Ataxin 2 SM domain LicD PF04991.8 CAR29150.1 - 1.9e-44 152.2 4.9 1.9e-44 152.2 3.4 2.3 2 0 0 2 2 2 1 LicD family CN_hydrolase PF00795.17 CAR29151.1 - 3.6e-13 49.2 0.0 5.4e-13 48.7 0.0 1.4 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase PRCC PF10253.4 CAR29152.1 - 0.013 16.2 7.4 0.041 14.5 5.2 1.7 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting PhdYeFM_antitox PF02604.14 CAR29152.1 - 0.021 14.4 0.1 0.036 13.6 0.1 1.5 1 0 0 1 1 1 0 Antitoxin Phd_YefM, type II toxin-antitoxin system SOBP PF15279.1 CAR29152.1 - 0.028 14.8 2.9 0.035 14.4 2.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein TFIIS_C PF01096.13 CAR29153.1 - 6.8e-19 67.2 1.3 6.8e-19 67.2 0.9 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 CAR29153.1 - 1.2e-11 44.1 10.8 2.4e-10 39.9 0.5 3.0 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit Lar_restr_allev PF14354.1 CAR29153.1 - 2.1e-05 24.7 6.8 0.00026 21.2 0.5 2.7 2 1 1 3 3 3 1 Restriction alleviation protein Lar TF_Zn_Ribbon PF08271.7 CAR29153.1 - 0.00019 20.6 6.4 0.0083 15.4 1.7 2.7 2 1 0 2 2 2 1 TFIIB zinc-binding DZR PF12773.2 CAR29153.1 - 0.00091 18.9 7.9 0.097 12.5 0.2 3.0 2 1 0 2 2 2 2 Double zinc ribbon zf-ribbon_3 PF13248.1 CAR29153.1 - 0.0018 17.4 8.4 1.1 8.6 0.1 4.2 4 0 0 4 4 4 1 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 CAR29153.1 - 0.0025 17.5 5.3 0.0082 15.9 0.8 2.4 2 0 0 2 2 2 1 Transposase zinc-ribbon domain zinc_ribbon_4 PF13717.1 CAR29153.1 - 0.0034 17.0 10.8 1.1 9.0 0.6 3.4 3 0 0 3 3 3 2 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CAR29153.1 - 0.005 16.3 10.6 1.3 8.6 0.6 3.4 3 0 0 3 3 3 2 zinc-ribbon domain Baculo_LEF5_C PF11792.3 CAR29153.1 - 0.022 14.1 1.5 0.022 14.1 1.0 2.5 2 1 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain zf-DNA_Pol PF08996.5 CAR29153.1 - 0.025 13.9 3.5 0.25 10.6 0.2 2.1 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger zf-TFIIB PF13453.1 CAR29153.1 - 0.027 13.6 1.0 0.027 13.6 0.7 2.3 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-C4_Topoisom PF01396.14 CAR29153.1 - 0.033 13.6 2.1 0.033 13.6 1.5 3.0 2 2 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Elf1 PF05129.8 CAR29153.1 - 0.033 13.8 4.1 0.49 10.1 0.3 2.4 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Rubredoxin PF00301.15 CAR29153.1 - 0.033 14.0 6.8 2.4 8.1 0.5 3.4 3 0 0 3 3 3 0 Rubredoxin DUF2387 PF09526.5 CAR29153.1 - 0.049 13.5 0.4 0.049 13.5 0.3 2.5 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) zf-C3HC4_3 PF13920.1 CAR29153.1 - 0.05 13.2 2.8 3.7 7.2 0.1 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Terminase_GpA PF05876.7 CAR29153.1 - 0.053 11.8 2.8 0.044 12.1 0.7 1.6 1 1 0 2 2 2 0 Phage terminase large subunit (GpA) Mu-like_Com PF10122.4 CAR29153.1 - 0.064 12.3 0.4 7.5 5.7 0.1 2.4 2 0 0 2 2 2 0 Mu-like prophage protein Com OrfB_Zn_ribbon PF07282.6 CAR29153.1 - 0.091 12.4 7.7 3.9 7.2 1.8 2.7 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Stc1 PF12898.2 CAR29153.1 - 0.15 12.1 0.4 0.15 12.1 0.3 2.3 1 1 1 2 2 2 0 Stc1 domain C1_1 PF00130.17 CAR29153.1 - 0.16 11.7 5.3 0.62 9.8 0.1 2.5 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3716 PF12511.3 CAR29153.1 - 0.18 11.4 1.8 1.2 8.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) Ogr_Delta PF04606.7 CAR29153.1 - 0.2 11.3 7.0 0.56 9.9 2.3 2.5 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger RRN7 PF11781.3 CAR29153.1 - 0.2 11.1 6.4 6 6.4 0.3 3.4 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 Zn-ribbon_8 PF09723.5 CAR29153.1 - 0.23 11.4 13.4 3.5 7.6 0.1 3.5 3 1 0 3 3 3 0 Zinc ribbon domain zf-C3HC4_4 PF15227.1 CAR29153.1 - 0.31 10.9 4.3 0.68 9.8 0.2 2.9 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING zinc_ribbon_2 PF13240.1 CAR29153.1 - 0.35 10.4 17.0 2.5 7.6 1.4 4.1 3 1 0 4 4 4 0 zinc-ribbon domain zf-H2C2_2 PF13465.1 CAR29153.1 - 0.59 10.5 6.2 2 8.8 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger double domain zf-CHY PF05495.7 CAR29153.1 - 0.69 10.1 7.3 4.6 7.4 0.1 2.6 2 1 0 2 2 2 0 CHY zinc finger zf-ISL3 PF14690.1 CAR29153.1 - 0.7 9.9 6.9 0.71 9.9 0.4 3.0 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 GATA PF00320.22 CAR29153.1 - 0.85 9.0 8.0 0.41 10.0 1.1 2.8 3 0 0 3 3 3 0 GATA zinc finger CpXC PF14353.1 CAR29153.1 - 1 9.3 7.8 2.2 8.2 0.0 3.1 1 1 2 3 3 3 0 CpXC protein PolC_DP2 PF03833.8 CAR29153.1 - 1.5 6.4 4.1 0.44 8.1 0.5 1.7 1 1 1 2 2 2 0 DNA polymerase II large subunit DP2 DUF2072 PF09845.4 CAR29153.1 - 1.6 8.6 5.0 1.6 8.6 0.1 2.8 2 1 1 3 3 3 0 Zn-ribbon containing protein (DUF2072) HypA PF01155.14 CAR29153.1 - 2 8.1 8.7 1.4 8.6 1.8 2.8 1 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family zf-C2H2_4 PF13894.1 CAR29153.1 - 2.1 8.8 8.9 44 4.7 0.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger NOB1_Zn_bind PF08772.6 CAR29153.1 - 5.8 6.8 6.6 5.5 6.8 0.2 3.1 3 1 1 4 4 4 0 Nin one binding (NOB1) Zn-ribbon like zf-AN1 PF01428.11 CAR29153.1 - 6.6 6.7 9.1 49 3.9 0.7 3.4 3 1 0 3 3 3 0 AN1-like Zinc finger Cpn60_TCP1 PF00118.19 CAR29154.1 - 9.8e-143 476.2 4.4 1.1e-142 476.0 3.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Resolvase PF00239.16 CAR29154.1 - 0.047 13.5 0.2 2 8.2 0.1 2.5 2 0 0 2 2 2 0 Resolvase, N terminal domain YbjQ_1 PF01906.12 CAR29154.1 - 0.078 13.4 0.1 0.5 10.8 0.0 2.4 3 0 0 3 3 3 0 Putative heavy-metal-binding Actin PF00022.14 CAR29155.1 - 3.8e-92 308.7 0.0 9.3e-92 307.4 0.0 1.6 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CAR29155.1 - 2.2e-06 26.4 0.0 0.001 17.7 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein NOZZLE PF08744.5 CAR29155.1 - 0.049 12.9 1.8 0.082 12.2 1.2 1.3 1 0 0 1 1 1 0 Plant transcription factor NOZZLE FAT PF02259.18 CAR29156.1 - 3.2e-139 463.8 0.0 3.2e-139 463.8 0.0 2.2 3 0 0 3 3 3 1 FAT domain DUF3385 PF11865.3 CAR29156.1 - 3.1e-65 218.9 0.5 3.1e-65 218.9 0.3 4.7 5 1 0 5 5 5 1 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.22 CAR29156.1 - 3.5e-61 206.6 0.1 6.7e-61 205.7 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 CAR29156.1 - 3.1e-41 139.5 5.3 4.2e-41 139.0 0.3 3.4 3 0 0 3 3 3 1 Rapamycin binding domain FATC PF02260.15 CAR29156.1 - 2.8e-19 68.2 0.5 6.6e-19 67.0 0.3 1.7 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.1 CAR29156.1 - 2.6e-15 56.4 7.8 0.081 13.2 0.0 8.6 6 1 2 8 8 8 4 HEAT repeats HEAT_EZ PF13513.1 CAR29156.1 - 2.2e-09 37.4 3.6 0.00014 22.1 0.0 7.7 9 2 0 9 9 7 1 HEAT-like repeat HEAT PF02985.17 CAR29156.1 - 4.8e-07 29.3 0.1 0.051 13.6 0.0 6.3 5 0 0 5 5 5 1 HEAT repeat DUF3437 PF11919.3 CAR29156.1 - 0.029 14.0 0.0 1.5 8.6 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) HrpB1_HrpK PF09613.5 CAR29156.1 - 0.047 13.1 0.0 0.28 10.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) Vac14_Fab1_bd PF12755.2 CAR29156.1 - 0.13 12.6 5.4 15 6.0 0.0 5.2 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region Yae1_N PF09811.4 CAR29157.1 - 1.4e-11 43.6 0.1 2.1e-11 43.1 0.1 1.2 1 0 0 1 1 1 1 Essential protein Yae1, N terminal AAA PF00004.24 CAR29158.1 - 5.9e-16 58.8 0.0 2.8e-15 56.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 CAR29158.1 - 4.8e-15 55.3 0.0 9.8e-15 54.3 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 CAR29158.1 - 2.3e-14 53.3 0.0 4.8e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 CAR29158.1 - 2.9e-09 36.1 0.1 5.9e-07 28.5 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 CAR29158.1 - 1.3e-06 28.5 0.0 7.4e-06 26.1 0.0 2.2 2 2 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CAR29158.1 - 5.7e-06 25.5 0.0 1.3e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CAR29158.1 - 1.9e-05 24.5 0.0 4.3e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CAR29158.1 - 2.1e-05 24.2 0.0 3e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CAR29158.1 - 2.9e-05 24.1 0.1 0.0026 17.7 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.16 CAR29158.1 - 0.00018 20.7 0.0 0.0069 15.5 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 CAR29158.1 - 0.00031 20.3 0.0 0.00075 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CAR29158.1 - 0.00036 20.2 0.0 0.00075 19.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain DNA_pol3_gamma3 PF12169.3 CAR29158.1 - 0.00052 19.7 0.1 0.0014 18.4 0.0 1.8 2 0 0 2 2 1 1 DNA polymerase III subunits gamma and tau domain III AAA_30 PF13604.1 CAR29158.1 - 0.0016 18.0 0.0 0.0039 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CAR29158.1 - 0.0023 18.7 0.0 0.0088 16.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 CAR29158.1 - 0.0026 18.1 0.2 0.0099 16.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 CAR29158.1 - 0.0026 16.7 0.0 0.005 15.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DNA_pol3_delta PF06144.8 CAR29158.1 - 0.0047 16.4 0.1 0.011 15.2 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase III, delta subunit DUF815 PF05673.8 CAR29158.1 - 0.0073 15.2 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 CAR29158.1 - 0.017 14.8 0.1 0.08 12.6 0.0 2.1 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 CAR29158.1 - 0.026 14.2 0.1 0.52 9.9 0.0 2.5 2 1 0 2 2 2 0 Archaeal ATPase AAA_3 PF07726.6 CAR29158.1 - 0.028 14.0 0.0 0.21 11.1 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 CAR29158.1 - 0.036 14.3 0.0 0.12 12.6 0.0 2.0 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 CAR29158.1 - 0.038 14.1 0.0 0.092 12.9 0.0 1.8 1 1 0 1 1 1 0 RNA helicase ResIII PF04851.10 CAR29158.1 - 0.054 13.3 0.1 0.22 11.3 0.0 2.1 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_28 PF13521.1 CAR29158.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Xpo1 PF08389.7 CAR29160.1 - 3.2e-36 124.4 1.1 3.2e-36 124.4 0.8 4.0 4 0 0 4 4 4 1 Exportin 1-like protein ATP-gua_PtransN PF02807.10 CAR29160.1 - 0.00028 20.9 3.3 0.096 12.8 0.0 3.3 4 0 0 4 4 4 2 ATP:guanido phosphotransferase, N-terminal domain 7TMR-HDED PF07697.6 CAR29160.1 - 0.0013 18.5 1.4 0.085 12.5 0.0 2.4 2 0 0 2 2 2 2 7TM-HD extracellular Ham1p_like PF01725.11 CAR29161.1 - 1.7e-49 167.7 0.0 1.9e-49 167.6 0.0 1.0 1 0 0 1 1 1 1 Ham1 family HEAT_2 PF13646.1 CAR29162.1 - 4.1e-31 107.0 0.6 8.6e-15 54.7 0.0 3.3 2 1 1 3 3 3 2 HEAT repeats HEAT_PBS PF03130.11 CAR29162.1 - 1.2e-17 62.5 0.0 0.00016 21.8 0.0 6.1 6 0 0 6 6 6 4 PBS lyase HEAT-like repeat HEAT PF02985.17 CAR29162.1 - 3.5e-12 45.3 0.6 0.046 13.7 0.0 6.4 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 CAR29162.1 - 3.5e-06 27.3 4.4 0.5 10.9 0.0 5.3 3 2 3 6 6 6 4 HEAT-like repeat Arm PF00514.18 CAR29162.1 - 0.00047 19.8 0.1 0.039 13.7 0.0 2.8 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat DUF4535 PF15054.1 CAR29162.1 - 0.0023 17.2 0.2 0.0053 16.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4535) Cohesin_HEAT PF12765.2 CAR29162.1 - 0.012 15.5 0.2 1.4 9.0 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion PAC2 PF09754.4 CAR29163.1 - 5.6e-34 117.9 0.1 7.2e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 PAC2 family Alpha-amylase PF00128.19 CAR29163.1 - 0.0078 15.6 0.1 0.0093 15.3 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain ATP_bind_1 PF03029.12 CAR29164.1 - 2.1e-82 276.2 0.0 3.4e-82 275.5 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 CAR29164.1 - 8.7e-06 25.2 0.1 0.00029 20.3 0.1 2.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 CAR29164.1 - 7.7e-05 22.8 0.1 0.001 19.2 0.0 2.7 3 1 1 4 4 4 1 AAA domain AAA_17 PF13207.1 CAR29164.1 - 0.00015 22.5 0.3 0.0016 19.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain CbiA PF01656.18 CAR29164.1 - 0.00022 20.7 0.1 0.00061 19.2 0.0 1.8 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.1 CAR29164.1 - 0.00048 20.0 0.0 0.0012 18.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 CAR29164.1 - 0.00061 19.7 0.0 0.0017 18.2 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_10 PF12846.2 CAR29164.1 - 0.00075 19.0 0.5 0.0072 15.8 0.3 2.1 1 1 0 1 1 1 1 AAA-like domain NACHT PF05729.7 CAR29164.1 - 0.00097 18.8 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain FeoB_N PF02421.13 CAR29164.1 - 0.0021 17.3 0.0 0.1 11.8 0.0 2.7 3 0 0 3 3 3 1 Ferrous iron transport protein B SRP54 PF00448.17 CAR29164.1 - 0.0053 16.2 0.0 0.056 12.8 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain PduV-EutP PF10662.4 CAR29164.1 - 0.0054 16.2 0.1 0.043 13.2 0.0 2.4 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 CAR29164.1 - 0.0059 17.0 0.5 0.3 11.6 0.0 2.6 2 1 0 2 2 1 1 Miro-like protein cobW PF02492.14 CAR29164.1 - 0.0092 15.4 0.6 0.22 10.9 0.0 2.8 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 CAR29164.1 - 0.013 15.1 0.0 0.036 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 CAR29164.1 - 0.018 14.2 0.1 0.58 9.3 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 CAR29164.1 - 0.032 14.2 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 CAR29164.1 - 0.034 14.4 1.3 0.22 11.8 0.0 2.6 2 2 0 2 2 2 0 AAA domain Septin PF00735.13 CAR29164.1 - 0.037 13.0 0.1 0.16 10.9 0.1 2.0 1 1 0 1 1 1 0 Septin MobB PF03205.9 CAR29164.1 - 0.038 13.6 0.0 0.092 12.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B KTI12 PF08433.5 CAR29164.1 - 0.041 13.0 0.0 0.079 12.1 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_30 PF13604.1 CAR29164.1 - 0.044 13.3 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 CAR29164.1 - 0.053 12.3 0.0 0.13 11.1 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain DUF87 PF01935.12 CAR29164.1 - 0.056 13.2 0.1 5 6.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 ArgK PF03308.11 CAR29164.1 - 0.074 11.8 0.0 0.67 8.6 0.0 2.2 2 1 0 2 2 2 0 ArgK protein RNA_helicase PF00910.17 CAR29164.1 - 0.092 12.9 0.3 1.4 9.1 0.0 2.8 3 0 0 3 3 3 0 RNA helicase Glyco_tranf_2_3 PF13641.1 CAR29164.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 SRPRB PF09439.5 CAR29164.1 - 0.25 10.5 3.1 0.53 9.4 0.0 2.5 3 0 0 3 3 2 0 Signal recognition particle receptor beta subunit DUF106 PF01956.11 CAR29165.1 - 2.5e-54 183.3 0.4 3e-54 183.0 0.3 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 CobN-Mg_chel PF02514.11 CAR29166.1 - 0.0057 14.1 0.1 0.0073 13.7 0.1 1.0 1 0 0 1 1 1 1 CobN/Magnesium Chelatase NSP11 PF06471.7 CAR29166.1 - 0.12 10.6 0.1 0.15 10.2 0.1 1.1 1 0 0 1 1 1 0 NSP11 PEMT PF04191.8 CAR29167.1 - 9.3e-33 112.5 3.3 2e-32 111.4 2.3 1.5 1 0 0 1 1 1 1 Phospholipid methyltransferase Steroid_dh PF02544.11 CAR29167.1 - 0.034 13.9 0.4 0.034 13.9 0.3 1.6 2 1 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase ABC_membrane PF00664.18 CAR29168.1 - 6.8e-81 271.6 33.0 6.3e-41 140.5 9.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CAR29168.1 - 9e-63 210.6 0.0 3.5e-33 114.8 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CAR29168.1 - 8.2e-13 48.0 5.8 0.0003 20.0 0.0 4.3 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 CAR29168.1 - 6.2e-09 34.9 0.1 0.0057 15.2 0.0 3.8 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_10 PF12846.2 CAR29168.1 - 1.1e-08 34.9 0.1 0.18 11.1 0.0 4.2 4 0 0 4 4 4 2 AAA-like domain DUF258 PF03193.11 CAR29168.1 - 1.5e-08 34.0 0.0 0.0033 16.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 CAR29168.1 - 1.7e-07 31.4 0.9 0.18 11.9 0.3 4.2 3 1 0 3 3 3 2 AAA domain AAA_21 PF13304.1 CAR29168.1 - 2.6e-07 30.9 7.8 0.33 10.8 1.8 4.6 3 2 0 4 4 3 3 AAA domain AAA_16 PF13191.1 CAR29168.1 - 3.3e-07 30.4 0.0 0.0077 16.2 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 CAR29168.1 - 5.6e-07 30.4 0.1 0.042 14.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CAR29168.1 - 6.8e-07 28.7 0.9 0.018 14.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.1 CAR29168.1 - 1.8e-05 25.0 0.1 0.22 11.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 CAR29168.1 - 1.9e-05 24.6 1.0 0.034 14.1 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase RNA_helicase PF00910.17 CAR29168.1 - 0.00023 21.3 0.1 0.31 11.2 0.0 3.4 3 0 0 3 3 2 1 RNA helicase Miro PF08477.8 CAR29168.1 - 0.0011 19.5 0.1 0.65 10.5 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein MobB PF03205.9 CAR29168.1 - 0.0017 18.0 0.3 1.1 9.0 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 CAR29168.1 - 0.0022 17.7 0.0 0.61 9.8 0.0 3.3 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) DUF87 PF01935.12 CAR29168.1 - 0.0024 17.7 0.3 0.45 10.2 0.0 2.9 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_25 PF13481.1 CAR29168.1 - 0.0053 16.1 0.0 2.6 7.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 CAR29168.1 - 0.0054 15.6 0.1 1.9 7.3 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NACHT PF05729.7 CAR29168.1 - 0.0064 16.1 0.2 0.35 10.4 0.0 2.8 3 0 0 3 3 2 1 NACHT domain FtsK_SpoIIIE PF01580.13 CAR29168.1 - 0.014 14.9 0.0 1.6 8.1 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AIG1 PF04548.11 CAR29168.1 - 0.014 14.5 0.1 3 6.8 0.1 2.7 2 0 0 2 2 2 0 AIG1 family AAA_14 PF13173.1 CAR29168.1 - 0.014 15.2 0.1 1.7 8.5 0.0 3.5 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 CAR29168.1 - 0.018 14.1 0.0 1.1 8.2 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.1 CAR29168.1 - 0.019 14.8 0.0 5.3 6.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 CAR29168.1 - 0.03 14.6 3.3 2 8.6 0.0 3.2 4 0 0 4 4 2 0 AAA domain AAA PF00004.24 CAR29168.1 - 0.046 13.9 0.3 8.8 6.5 0.0 4.1 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) PRK PF00485.13 CAR29168.1 - 0.073 12.6 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_30 PF13604.1 CAR29168.1 - 0.11 12.1 0.0 3.3 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 CAR29168.1 - 0.12 11.8 0.0 0.97 8.8 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.1 CAR29168.1 - 0.15 12.0 0.0 35 4.3 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.18 CAR29168.1 - 0.42 10.4 3.0 8.7 6.1 0.0 2.6 2 0 0 2 2 2 0 Dynamin family ThiF PF00899.16 CAR29169.1 - 1.1e-52 177.4 0.2 3.2e-30 104.7 0.0 2.4 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 CAR29169.1 - 9.6e-43 145.3 0.1 5.7e-42 142.8 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 CAR29169.1 - 4.1e-36 122.3 0.6 1e-22 79.4 0.1 2.5 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CAR29169.1 - 1.2e-24 85.4 0.5 1.7e-20 72.1 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Mog1 PF04603.7 CAR29170.1 - 7e-19 68.1 0.2 8.9e-13 48.3 0.0 2.6 1 1 1 2 2 2 2 Ran-interacting Mog1 protein Gly_transf_sug PF04488.10 CAR29171.1 - 8.4e-13 48.5 0.2 4.3e-12 46.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif BBP1_C PF15272.1 CAR29171.1 - 0.0032 17.0 3.3 0.0047 16.5 2.3 1.3 1 0 0 1 1 1 1 Spindle pole body component BBP1, C-terminal DUF3373 PF11853.3 CAR29171.1 - 0.093 11.2 0.0 0.11 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) OmpH PF03938.9 CAR29171.1 - 0.29 11.0 8.1 0.5 10.2 5.6 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) V_ATPase_I PF01496.14 CAR29171.1 - 0.42 8.3 2.4 0.58 7.9 1.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Septin PF00735.13 CAR29172.1 - 1.2e-104 349.2 0.0 2.1e-104 348.4 0.0 1.4 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 CAR29172.1 - 3.5e-08 33.3 0.0 6.4e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CAR29172.1 - 5.9e-06 26.2 6.0 0.00055 19.7 0.2 2.9 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 CAR29172.1 - 2e-05 23.8 1.1 7.9e-05 21.8 0.8 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 CAR29172.1 - 3.9e-05 22.8 0.1 9.5e-05 21.6 0.0 1.6 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.8 CAR29172.1 - 0.00058 18.7 0.1 0.0012 17.7 0.1 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Miro PF08477.8 CAR29172.1 - 0.0013 19.2 0.7 0.0025 18.3 0.1 1.8 2 0 0 2 2 2 1 Miro-like protein ABC_tran PF00005.22 CAR29172.1 - 0.0024 18.1 0.4 0.0082 16.4 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_10 PF12846.2 CAR29172.1 - 0.017 14.5 0.0 0.033 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain Gasdermin PF04598.7 CAR29172.1 - 0.04 12.6 5.7 0.044 12.5 2.8 1.7 1 1 1 2 2 2 0 Gasdermin family AAA_17 PF13207.1 CAR29172.1 - 0.073 13.8 1.2 0.23 12.2 0.0 2.4 3 1 0 3 3 3 0 AAA domain FeoB_N PF02421.13 CAR29172.1 - 0.085 12.1 0.5 0.35 10.1 0.4 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B MobB PF03205.9 CAR29172.1 - 0.09 12.4 0.1 0.19 11.3 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 CAR29172.1 - 0.21 11.0 1.5 4.8 6.6 0.1 2.5 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation IGPS PF00218.16 CAR29173.1 - 4.4e-95 317.5 0.0 5.7e-95 317.1 0.0 1.1 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.23 CAR29173.1 - 1.1e-53 181.6 0.1 1.8e-53 180.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CAR29173.1 - 1e-10 41.4 0.1 2.3e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.14 CAR29173.1 - 8.7e-05 22.1 0.1 0.00021 20.8 0.1 1.6 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.16 CAR29173.1 - 0.011 15.0 0.0 0.027 13.7 0.0 1.6 2 0 0 2 2 2 0 Histidine biosynthesis protein PDZ PF00595.19 CAR29173.1 - 0.048 13.8 0.1 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) Syja_N PF02383.13 CAR29174.1 - 4.8e-85 285.1 0.6 6.2e-85 284.7 0.4 1.1 1 0 0 1 1 1 1 SacI homology domain PUL PF08324.6 CAR29175.1 - 2.9e-57 193.5 1.9 3.7e-57 193.1 1.3 1.1 1 0 0 1 1 1 1 PUL domain PFU PF09070.6 CAR29175.1 - 7.4e-44 148.4 0.3 1.5e-43 147.5 0.2 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 CAR29175.1 - 1.7e-34 116.4 22.0 5.1e-07 29.3 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 CAR29175.1 - 0.0013 18.4 3.0 0.75 9.5 0.0 3.9 4 1 0 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Tox-MPTase4 PF15640.1 CAR29175.1 - 0.092 12.3 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Metallopeptidase toxin 4 RRM_1 PF00076.17 CAR29176.1 - 0.00057 19.4 0.0 0.00089 18.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR29176.1 - 0.0012 18.7 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 CAR29176.1 - 0.0021 18.4 6.6 0.004 17.5 4.6 1.5 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 CAR29176.1 - 0.0032 17.2 0.0 0.0051 16.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4510 PF14971.1 CAR29176.1 - 0.11 12.6 0.3 0.18 11.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) Ku PF02735.11 CAR29177.1 - 1.9e-31 109.0 0.1 3.2e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 CAR29177.1 - 2.9e-15 56.3 0.0 6.5e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain PGM_PMM_I PF02878.11 CAR29178.1 - 3.9e-33 113.8 0.1 6.3e-33 113.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 CAR29178.1 - 2e-24 85.8 0.0 3.4e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 CAR29178.1 - 1.7e-13 50.7 0.0 4e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 CAR29178.1 - 3.1e-09 36.7 0.0 6.9e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF434 PF04256.7 CAR29178.1 - 0.15 11.4 0.0 0.35 10.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF434) Pkinase PF00069.20 CAR29179.1 - 2.2e-68 230.2 0.0 3e-68 229.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR29179.1 - 6.5e-31 107.3 0.0 9.3e-31 106.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 CAR29179.1 - 2.5e-10 40.7 0.2 7.1e-10 39.2 0.2 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 CAR29179.1 - 0.005 15.8 0.0 0.013 14.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CAR29179.1 - 0.084 11.9 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Hamartin PF04388.7 CAR29179.1 - 0.47 9.0 6.4 0.69 8.5 4.4 1.1 1 0 0 1 1 1 0 Hamartin protein RRN3 PF05327.6 CAR29180.1 - 1.8e-180 600.7 8.5 2.5e-180 600.3 5.9 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.7 CAR29180.1 - 1.7e-05 23.0 13.4 2.5e-05 22.4 9.3 1.3 1 0 0 1 1 1 1 Nop14-like family TFIIA PF03153.8 CAR29180.1 - 0.00018 21.5 8.5 0.00021 21.3 5.9 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.9 CAR29180.1 - 0.0037 15.3 11.5 0.0057 14.7 8.0 1.2 1 0 0 1 1 1 1 CDC45-like protein BUD22 PF09073.5 CAR29180.1 - 0.22 10.5 16.6 0.37 9.7 11.5 1.3 1 0 0 1 1 1 0 BUD22 Sigma70_ner PF04546.8 CAR29180.1 - 0.62 9.6 19.6 1.3 8.5 13.6 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region Daxx PF03344.10 CAR29180.1 - 1.4 7.3 25.9 2.2 6.6 17.9 1.2 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 CAR29180.1 - 1.5 8.1 15.9 2.5 7.3 11.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Astro_capsid PF03115.9 CAR29180.1 - 1.7 6.7 9.8 2.5 6.2 6.8 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor SDA1 PF05285.7 CAR29180.1 - 5.5 6.1 27.0 9.2 5.4 18.7 1.2 1 0 0 1 1 1 0 SDA1 SPRY PF00622.23 CAR29181.1 - 2.1e-13 50.4 0.0 4.8e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 SPRY domain CENP-T PF15511.1 CAR29181.1 - 0.22 10.6 13.9 0.027 13.7 5.3 2.0 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T SRP9-21 PF05486.7 CAR29182.1 - 1.2e-21 76.2 0.0 2.1e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) WD40 PF00400.27 CAR29183.1 - 7.8e-22 76.2 13.3 3.2e-07 29.9 0.0 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat Mito_carr PF00153.22 CAR29184.1 - 6.1e-59 195.7 5.1 6.4e-21 73.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Prenyltransf PF01255.14 CAR29185.1 - 1.2e-69 233.8 0.1 1.6e-69 233.4 0.1 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Vma12 PF11712.3 CAR29186.1 - 4.4e-35 120.4 0.5 4.4e-35 120.4 0.3 1.5 2 0 0 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DnaG_DnaB_bind PF08278.6 CAR29186.1 - 0.0014 18.8 1.6 0.0045 17.1 1.1 1.8 1 1 0 1 1 1 1 DNA primase DnaG DnaB-binding UbiA PF01040.13 CAR29186.1 - 0.01 15.0 0.0 0.014 14.6 0.0 1.1 1 0 0 1 1 1 0 UbiA prenyltransferase family Myb_CC_LHEQLE PF14379.1 CAR29186.1 - 0.013 15.0 0.4 0.013 15.0 0.3 2.5 2 0 0 2 2 2 0 MYB-CC type transfactor, LHEQLE motif TcdB_N PF12918.2 CAR29186.1 - 0.02 14.9 1.5 0.02 14.9 1.0 2.6 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain Attachment_P66 PF11263.3 CAR29186.1 - 0.033 13.2 0.1 4 6.3 0.0 2.2 2 0 0 2 2 2 0 Borrelia burgdorferi attachment protein P66 ATP_synt_I PF03899.10 CAR29186.1 - 0.036 14.2 2.2 0.051 13.7 1.5 1.2 1 0 0 1 1 1 0 ATP synthase I chain Pox_A14 PF05767.7 CAR29186.1 - 0.044 13.7 0.7 0.074 13.0 0.5 1.3 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 zf-MYND PF01753.13 CAR29187.1 - 4.8e-08 32.7 18.1 1.1e-07 31.5 12.5 1.7 1 1 0 1 1 1 1 MYND finger ABM PF03992.11 CAR29188.1 - 5.3e-12 45.6 0.4 6.9e-12 45.2 0.3 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF3365 PF11845.3 CAR29188.1 - 0.1 12.4 0.1 0.14 11.9 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3365) CS PF04969.11 CAR29189.1 - 0.00011 22.6 0.4 0.00021 21.7 0.0 1.7 2 0 0 2 2 2 1 CS domain AntA PF08346.7 CAR29189.1 - 0.065 13.4 0.1 6.7 6.9 0.0 2.3 2 0 0 2 2 2 0 AntA/AntB antirepressor Aldose_epim PF01263.15 CAR29190.1 - 1.3e-49 168.9 0.5 1.5e-49 168.7 0.3 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Pkinase PF00069.20 CAR29191.1 - 1.7e-53 181.4 0.0 2.4e-53 180.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR29191.1 - 7.2e-23 80.9 0.0 1.1e-21 77.1 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase AP_endonuc_2 PF01261.19 CAR29192.1 - 1.8e-30 105.8 0.0 2.3e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel XPG_N PF00752.12 CAR29193.1 - 1.5e-37 127.9 0.0 2.8e-37 127.0 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 CAR29193.1 - 2.3e-29 101.2 0.1 6.2e-29 99.8 0.1 1.8 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 CAR29193.1 - 7.5e-07 29.3 0.2 4.5e-06 26.8 0.0 2.4 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HXXSHH PF07586.6 CAR29193.1 - 0.087 11.7 0.1 0.16 10.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Asp PF00026.18 CAR29194.1 - 3.3e-73 246.6 4.4 5.1e-73 246.0 3.1 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CAR29194.1 - 5.2e-07 29.7 0.0 4.7e-06 26.6 0.0 2.6 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CAR29194.1 - 4e-05 24.0 0.4 3.1 8.3 0.0 3.7 3 1 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 CAR29194.1 - 5.5e-05 22.7 0.2 0.0046 16.5 0.1 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal RVP PF00077.15 CAR29194.1 - 0.019 14.8 0.1 2.5 8.0 0.0 2.8 3 0 0 3 3 3 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CAR29194.1 - 0.085 12.6 0.0 12 5.7 0.0 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease BAF1_ABF1 PF04684.8 CAR29195.1 - 3.5e-127 425.2 8.5 2.7e-116 389.3 0.0 2.6 1 1 2 3 3 3 2 BAF1 / ABF1 chromatin reorganising factor DBD_Tnp_Mut PF03108.10 CAR29195.1 - 0.001 18.5 0.1 0.0019 17.7 0.1 1.4 1 0 0 1 1 1 1 MuDR family transposase OAD_gamma PF04277.8 CAR29195.1 - 0.45 10.9 0.1 0.45 10.9 0.0 2.7 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain mRNA_stabil PF13929.1 CAR29196.1 - 1.8e-113 378.3 0.2 2.7e-113 377.7 0.1 1.3 1 0 0 1 1 1 1 mRNA stabilisation Oligomerisation PF02410.10 CAR29196.1 - 3.7e-18 65.3 0.0 7.3e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 Oligomerisation domain KTI12 PF08433.5 CAR29197.1 - 8.6e-95 316.9 0.0 9.8e-95 316.8 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.1 CAR29197.1 - 0.0003 21.0 0.4 0.0024 18.1 0.3 2.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CAR29197.1 - 0.00087 19.1 0.0 0.002 18.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CAR29197.1 - 0.005 16.9 0.0 0.022 14.9 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 CAR29197.1 - 0.0076 17.0 0.0 0.018 15.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CAR29197.1 - 0.01 15.8 0.1 0.083 12.8 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 CAR29197.1 - 0.045 13.9 0.1 0.22 11.7 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 CAR29197.1 - 0.063 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase RasGEF_N PF00618.15 CAR29197.1 - 0.1 12.6 0.1 2.4 8.3 0.0 2.4 2 0 0 2 2 2 0 RasGEF N-terminal motif MMR_HSR1 PF01926.18 CAR29198.1 - 2.3e-14 53.3 0.0 4.4e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CAR29198.1 - 2e-06 27.1 0.1 3.8e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 CAR29198.1 - 3.8e-06 26.1 0.2 6.2e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 CAR29198.1 - 0.00052 19.1 0.0 0.00088 18.4 0.0 1.4 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.8 CAR29198.1 - 0.011 14.6 0.3 0.017 13.9 0.2 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.18 CAR29198.1 - 0.022 14.5 0.8 1.4 8.7 0.2 2.4 1 1 1 2 2 2 0 Dynamin family ArgK PF03308.11 CAR29198.1 - 0.04 12.6 1.8 0.62 8.7 0.1 2.1 1 1 1 2 2 2 0 ArgK protein SRPRB PF09439.5 CAR29198.1 - 0.043 13.0 0.0 0.088 12.0 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NTPase_1 PF03266.10 CAR29198.1 - 0.056 13.1 0.1 0.096 12.3 0.1 1.4 1 0 0 1 1 1 0 NTPase Miro PF08477.8 CAR29198.1 - 0.059 13.8 0.1 0.22 12.0 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein AAA_29 PF13555.1 CAR29198.1 - 0.062 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.13 CAR29198.1 - 0.071 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_17 PF13207.1 CAR29198.1 - 0.074 13.8 0.2 0.53 11.1 0.0 2.3 2 1 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 CAR29198.1 - 0.17 11.2 0.3 0.74 9.2 0.2 2.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 CAR29198.1 - 0.19 12.0 0.6 0.65 10.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain Hap4_Hap_bind PF10297.4 CAR29200.1 - 3.1e-09 36.3 8.6 6.6e-09 35.3 5.9 1.6 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 SOR_SNZ PF01680.12 CAR29201.1 - 1.4e-107 358.0 6.8 1.8e-107 357.6 4.7 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 CAR29201.1 - 1.4e-08 34.0 1.0 1e-06 28.0 0.0 2.4 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG Dus PF01207.12 CAR29201.1 - 0.0029 16.5 1.0 1.4 7.7 0.0 2.9 2 1 1 3 3 3 2 Dihydrouridine synthase (Dus) Nitr_red_bet_C PF14711.1 CAR29201.1 - 0.0056 16.1 0.0 0.017 14.6 0.0 1.8 1 0 0 1 1 1 1 Respiratory nitrate reductase beta C-terminal His_biosynth PF00977.16 CAR29201.1 - 0.0063 15.8 0.1 0.067 12.4 0.0 2.1 2 0 0 2 2 2 1 Histidine biosynthesis protein NanE PF04131.9 CAR29201.1 - 0.01 14.7 1.4 0.11 11.4 0.0 2.7 2 1 1 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.10 CAR29201.1 - 0.012 14.8 1.3 0.018 14.1 0.0 2.0 2 1 0 2 2 2 0 Nitronate monooxygenase TMP-TENI PF02581.12 CAR29201.1 - 0.019 14.0 0.3 0.37 9.8 0.0 2.4 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI IGPS PF00218.16 CAR29201.1 - 0.031 13.3 0.2 0.24 10.4 0.0 2.4 2 1 1 3 3 3 0 Indole-3-glycerol phosphate synthase DUF4391 PF14335.1 CAR29201.1 - 0.047 13.0 0.1 0.068 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) Fapy_DNA_glyco PF01149.19 CAR29201.1 - 0.079 13.3 0.0 2.6 8.4 0.0 2.7 2 1 1 3 3 3 0 Formamidopyrimidine-DNA glycosylase N-terminal domain 1-cysPrx_C PF10417.4 CAR29201.1 - 0.098 12.3 0.4 5 6.8 0.0 2.7 2 0 0 2 2 2 0 C-terminal domain of 1-Cys peroxiredoxin SNO PF01174.14 CAR29202.1 - 1.1e-86 289.3 0.0 1.3e-86 289.1 0.0 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 CAR29202.1 - 7.9e-08 32.0 0.0 2.2e-07 30.5 0.0 1.7 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 CAR29202.1 - 3.4e-05 23.3 0.0 4.6e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I DUF4066 PF13278.1 CAR29202.1 - 0.0082 15.4 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DUF4154 PF13689.1 CAR29202.1 - 0.013 15.1 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4154) Peptidase_S51 PF03575.12 CAR29202.1 - 0.014 15.1 0.0 0.018 14.7 0.0 1.3 1 1 0 1 1 1 0 Peptidase family S51 BPL_N PF09825.4 CAR29202.1 - 0.025 13.3 0.0 0.044 12.5 0.0 1.4 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal DJ-1_PfpI PF01965.19 CAR29202.1 - 0.049 13.1 0.0 0.079 12.4 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family Matrix PF00661.16 CAR29202.1 - 0.14 10.4 0.0 0.19 9.9 0.0 1.1 1 0 0 1 1 1 0 Viral matrix protein Drc1-Sld2 PF11719.3 CAR29204.1 - 6.5e-57 193.5 38.5 2.5e-56 191.6 26.7 1.8 1 1 0 1 1 1 1 DNA replication and checkpoint protein PBP1_TM PF14812.1 CAR29204.1 - 0.33 11.2 10.5 3.8 7.8 1.7 3.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UTP15_C PF09384.5 CAR29205.1 - 9e-51 171.4 0.3 1.3e-50 170.9 0.2 1.2 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 CAR29205.1 - 4.2e-19 67.6 6.5 2.8e-05 23.7 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat WD40 PF00400.27 CAR29206.1 - 3.3e-28 96.4 17.7 0.00029 20.5 0.1 11.0 11 1 0 11 11 11 7 WD domain, G-beta repeat eIF2A PF08662.6 CAR29206.1 - 2.5e-08 33.8 0.1 6e-05 22.8 0.0 3.4 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 CAR29206.1 - 9.6e-06 25.2 0.5 0.0027 17.2 0.1 2.7 2 1 0 2 2 2 2 PQQ-like domain Gmad1 PF10647.4 CAR29206.1 - 0.019 14.3 0.1 19 4.5 0.0 3.2 3 0 0 3 3 3 0 Lipoprotein LpqB beta-propeller domain CRC_subunit PF08624.5 CAR29207.1 - 1.8e-55 186.6 0.1 3.2e-55 185.8 0.0 1.5 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit YL1 PF05764.8 CAR29207.1 - 2.3 7.7 15.8 4.6 6.7 11.0 1.5 1 0 0 1 1 1 0 YL1 nuclear protein Peptidase_M41 PF01434.13 CAR29208.1 - 1.5e-72 243.4 3.6 9.4e-72 240.9 0.0 2.2 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.24 CAR29208.1 - 1.4e-39 135.3 0.0 3.8e-39 133.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 CAR29208.1 - 1.4e-07 31.6 0.1 4.3e-07 30.0 0.0 1.9 1 0 0 1 1 1 1 FtsH Extracellular AAA_17 PF13207.1 CAR29208.1 - 0.00015 22.5 1.3 0.0026 18.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain UPF0233 PF06781.7 CAR29208.1 - 0.004 16.7 0.0 4.5 6.9 0.0 2.8 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0233) TIP49 PF06068.8 CAR29208.1 - 0.0073 15.0 0.0 0.016 13.9 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_22 PF13401.1 CAR29208.1 - 0.013 15.6 0.1 0.72 10.0 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 CAR29208.1 - 0.019 14.6 0.4 0.056 13.2 0.3 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 CAR29208.1 - 0.022 14.6 1.0 0.47 10.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain Fe-ADH_2 PF13685.1 CAR29208.1 - 0.03 13.6 0.1 0.43 9.8 0.0 2.5 3 0 0 3 3 3 0 Iron-containing alcohol dehydrogenase RuvB_N PF05496.7 CAR29208.1 - 0.034 13.1 0.0 0.066 12.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus RP-C_C PF11800.3 CAR29208.1 - 0.055 13.1 4.2 0.075 12.7 2.0 1.9 1 1 0 1 1 1 0 Replication protein C C-terminal region AAA_16 PF13191.1 CAR29208.1 - 0.069 13.1 0.1 0.23 11.3 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 CAR29208.1 - 0.14 11.8 3.7 0.31 10.7 0.0 3.0 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 CAR29208.1 - 0.15 12.3 0.0 0.15 12.3 0.0 3.2 2 1 0 2 2 1 0 AAA domain DUF883 PF05957.8 CAR29208.1 - 0.42 11.0 5.0 1.5 9.2 3.5 2.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) AAA_25 PF13481.1 CAR29208.1 - 1.7 7.9 6.4 0.39 10.0 0.5 2.7 2 1 1 3 3 3 0 AAA domain MFS_1 PF07690.11 CAR29209.1 - 3.6e-35 121.3 35.2 3.6e-35 121.3 24.4 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CAR29209.1 - 7.2e-15 54.4 8.4 7.2e-15 54.4 5.8 4.2 1 1 2 4 4 4 1 Sugar (and other) transporter Fzo_mitofusin PF04799.8 CAR29209.1 - 0.25 10.7 2.7 3 7.1 0.4 2.5 2 0 0 2 2 2 0 fzo-like conserved region Macro_2 PF14519.1 CAR29210.1 - 6.1e-98 327.3 0.0 7.1e-98 327.1 0.0 1.0 1 0 0 1 1 1 1 Macro-like domain Macro PF01661.16 CAR29210.1 - 0.0046 16.8 0.0 0.027 14.3 0.0 2.2 2 1 0 2 2 2 1 Macro domain Aminotran_1_2 PF00155.16 CAR29211.1 - 1.8e-86 290.3 0.0 2.1e-86 290.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II SIS PF01380.17 CAR29213.1 - 1.1e-60 202.9 0.0 6.3e-31 106.7 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 CAR29213.1 - 3.3e-29 101.7 0.1 5.8e-21 74.6 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 CAR29213.1 - 4.7e-18 65.4 0.0 1e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 CAR29213.1 - 5.7e-11 42.2 0.0 1.3e-10 41.0 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.1 CAR29213.1 - 4.8e-09 35.2 0.1 8.5e-09 34.4 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Peptidase_M18 PF02127.10 CAR29214.1 - 6.2e-140 466.5 0.0 7.2e-140 466.3 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Pkinase PF00069.20 CAR29215.1 - 1.9e-70 236.9 0.0 8.3e-70 234.8 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR29215.1 - 3.1e-34 118.2 0.0 1.7e-32 112.5 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase Choline_kinase PF01633.15 CAR29215.1 - 0.0023 17.5 1.9 0.011 15.3 0.0 2.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 CAR29215.1 - 0.0072 16.0 0.0 0.033 13.9 0.0 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CAR29215.1 - 0.012 14.7 0.0 0.024 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ADH_N PF08240.7 CAR29216.1 - 1.2e-29 102.2 1.2 2e-29 101.5 0.8 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CAR29216.1 - 2.4e-28 98.2 0.3 3.4e-28 97.7 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CAR29216.1 - 0.00021 22.1 0.0 0.00041 21.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2284 PF10050.4 CAR29216.1 - 0.098 12.2 0.2 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) YbjQ_1 PF01906.12 CAR29216.1 - 0.12 12.7 0.3 0.31 11.4 0.1 1.8 2 0 0 2 2 2 0 Putative heavy-metal-binding ADH_N PF08240.7 CAR29217.1 - 3e-28 97.7 1.3 5.1e-28 97.0 0.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CAR29217.1 - 1.9e-22 79.1 0.1 3e-22 78.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CAR29217.1 - 2.8e-09 37.9 0.0 5.1e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Metallophos PF00149.23 CAR29218.1 - 3.8e-40 137.4 0.0 5.8e-40 136.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CAR29218.1 - 0.0013 18.5 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Sulfatase PF00884.18 CAR29219.1 - 3e-63 213.8 0.0 4.2e-63 213.3 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 CAR29219.1 - 0.00037 19.9 0.0 0.0016 17.8 0.0 2.0 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 CAR29219.1 - 0.0015 17.0 0.0 0.0017 16.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) PHD PF00628.24 CAR29220.1 - 9e-11 41.3 8.0 1.6e-10 40.5 5.5 1.4 1 0 0 1 1 1 1 PHD-finger Sec1 PF00995.18 CAR29221.1 - 8.3e-141 470.3 8.0 9.4e-141 470.2 5.5 1.0 1 0 0 1 1 1 1 Sec1 family HHH_6 PF14579.1 CAR29221.1 - 0.0094 15.9 0.0 0.028 14.4 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif YxiJ PF14176.1 CAR29221.1 - 0.014 15.4 0.9 1.3 9.1 0.1 2.9 2 1 0 2 2 2 0 YxiJ-like protein LAGLIDADG_1 PF00961.14 CAR29221.1 - 0.18 12.3 0.2 0.18 12.3 0.2 3.0 2 1 1 3 3 3 0 LAGLIDADG endonuclease TCO89 PF10452.4 CAR29222.1 - 2.2e-138 462.8 64.2 6.3e-137 458.0 44.5 2.1 1 1 0 1 1 1 1 TORC1 subunit TCO89 UCH_1 PF13423.1 CAR29223.1 - 1.3e-63 215.1 2.6 2e-63 214.6 1.8 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 CAR29223.1 - 1.4e-21 77.4 0.0 2.8e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Exonuclease WD40 PF00400.27 CAR29223.1 - 0.00028 20.6 0.1 0.1 12.5 0.0 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat RBP_receptor PF14752.1 CAR29223.1 - 0.039 12.3 0.0 0.055 11.7 0.0 1.1 1 0 0 1 1 1 0 Retinol binding protein receptor WD40 PF00400.27 CAR29224.1 - 1.1e-25 88.5 17.7 2e-07 30.6 0.0 8.8 9 0 0 9 9 9 5 WD domain, G-beta repeat Nup160 PF11715.3 CAR29224.1 - 1.5e-06 26.6 8.7 0.00012 20.3 0.3 4.1 3 1 1 4 4 4 3 Nucleoporin Nup120/160 KH_1 PF00013.24 CAR29226.1 - 4e-09 35.9 0.0 0.00048 19.7 0.0 3.2 3 0 0 3 3 3 2 KH domain KH_3 PF13014.1 CAR29226.1 - 3.2e-08 33.0 0.0 0.0024 17.4 0.0 3.4 3 0 0 3 3 3 2 KH domain Abhydrolase_5 PF12695.2 CAR29227.1 - 1.6e-19 70.0 0.0 2.3e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CAR29227.1 - 1.3e-17 64.4 0.0 1.7e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CAR29227.1 - 1.1e-13 50.7 0.0 3.4e-13 49.2 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 CAR29227.1 - 1.2e-09 38.0 0.0 1.6e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 CAR29227.1 - 0.0011 18.2 0.0 0.75 9.0 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family LCAT PF02450.10 CAR29227.1 - 0.021 13.7 0.0 0.039 12.9 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Esterase PF00756.15 CAR29227.1 - 0.031 13.6 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative esterase DUF3530 PF12048.3 CAR29227.1 - 0.092 11.7 0.0 0.17 10.8 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) Thioesterase PF00975.15 CAR29227.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Peptidase_S9 PF00326.16 CAR29227.1 - 0.12 11.5 0.2 0.49 9.5 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family UPF1_Zn_bind PF09416.5 CAR29229.1 - 1.7e-68 228.9 7.2 1.7e-68 228.9 5.0 2.2 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 CAR29229.1 - 4.1e-59 199.3 0.0 6.8e-59 198.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CAR29229.1 - 4e-50 170.5 0.8 4e-50 170.5 0.6 1.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 CAR29229.1 - 1.9e-14 53.7 0.2 2.4e-13 50.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CAR29229.1 - 5.3e-14 51.7 0.0 2.3e-13 49.6 0.1 2.0 2 0 0 2 2 2 1 Part of AAA domain DUF2075 PF09848.4 CAR29229.1 - 4.2e-05 22.6 0.4 0.00024 20.1 0.0 2.5 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 CAR29229.1 - 0.00026 20.8 0.0 0.00064 19.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 CAR29229.1 - 0.00072 19.1 0.0 0.63 9.5 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 CAR29229.1 - 0.0025 17.4 0.0 0.005 16.4 0.0 1.5 1 0 0 1 1 1 1 Helicase PhoH PF02562.11 CAR29229.1 - 0.0089 15.2 0.0 0.022 14.0 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein T2SE PF00437.15 CAR29229.1 - 0.052 12.4 0.0 0.097 11.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PIF1 PF05970.9 CAR29229.1 - 0.06 12.2 0.0 6 5.7 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase DEAD PF00270.24 CAR29229.1 - 0.065 12.7 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_16 PF13191.1 CAR29229.1 - 0.16 11.9 1.4 0.18 11.7 0.1 1.7 2 0 0 2 2 2 0 AAA ATPase domain RasGAP PF00616.14 CAR29230.1 - 1.2e-44 152.3 2.0 1.4e-44 152.1 0.2 2.1 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 CAR29230.1 - 8.1e-05 22.3 0.0 0.00017 21.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain CRAL_TRIO PF00650.15 CAR29231.1 - 9.2e-37 125.9 0.1 1.4e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CAR29231.1 - 1.5e-12 47.4 0.4 4.1e-12 46.0 0.3 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 CAR29231.1 - 0.00046 20.1 0.1 0.00088 19.2 0.1 1.4 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain AAA PF00004.24 CAR29232.1 - 1.4e-12 47.9 0.0 3.2e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CAR29232.1 - 1.5e-09 37.1 0.4 5.9e-05 21.9 0.0 2.8 2 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 CAR29232.1 - 7.6e-05 23.5 0.2 0.00042 21.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CAR29232.1 - 9.2e-05 22.6 0.0 0.00054 20.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CAR29232.1 - 0.00011 21.2 0.0 0.00035 19.7 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CAR29232.1 - 0.00019 21.3 0.0 0.043 13.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CAR29232.1 - 0.00036 20.5 0.0 0.0016 18.4 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 CAR29232.1 - 0.0019 18.0 0.8 0.0035 17.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 CAR29232.1 - 0.0035 17.0 0.0 0.0084 15.8 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain DUF258 PF03193.11 CAR29232.1 - 0.0036 16.4 0.0 0.0069 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 RNA_helicase PF00910.17 CAR29232.1 - 0.0044 17.1 0.0 0.016 15.3 0.0 2.0 2 0 0 2 2 1 1 RNA helicase AAA_5 PF07728.9 CAR29232.1 - 0.021 14.5 0.2 0.068 12.8 0.0 2.1 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 CAR29232.1 - 0.023 14.9 0.9 0.18 12.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_11 PF13086.1 CAR29232.1 - 0.079 12.5 0.1 0.17 11.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 CAR29232.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF4261 PF14080.1 CAR29232.1 - 0.12 12.1 0.1 0.98 9.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4261) Snf7 PF03357.16 CAR29233.1 - 9.2e-29 100.0 7.4 1.1e-28 99.7 5.1 1.1 1 0 0 1 1 1 1 Snf7 TPR_19 PF14559.1 CAR29233.1 - 0.097 13.0 0.1 0.49 10.7 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DnaJ-X PF14308.1 CAR29234.1 - 3.9e-64 215.6 14.0 6.8e-64 214.8 2.9 2.4 2 0 0 2 2 2 2 X-domain of DnaJ-containing DnaJ PF00226.26 CAR29234.1 - 3.7e-25 87.4 1.3 1.6e-24 85.3 0.9 2.2 1 0 0 1 1 1 1 DnaJ domain EMP70 PF02990.11 CAR29234.1 - 0.18 10.2 3.2 0.26 9.7 2.2 1.2 1 0 0 1 1 1 0 Endomembrane protein 70 Atg14 PF10186.4 CAR29234.1 - 1.6 7.5 12.1 3 6.6 8.4 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Neur_chan_memb PF02932.11 CAR29234.1 - 2.8 7.7 7.0 1.8 8.3 3.0 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF3450 PF11932.3 CAR29234.1 - 3.4 6.8 18.5 3.3 6.9 7.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) DUF3210 PF11489.3 CAR29235.1 - 1.7e-10 40.2 97.6 1.7e-10 40.2 67.7 7.1 1 1 5 6 6 6 3 Protein of unknown function (DUF3210) NTF2 PF02136.15 CAR29236.1 - 2.3e-35 121.5 0.3 2.5e-35 121.3 0.2 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4518 PF15008.1 CAR29236.1 - 0.0023 17.0 0.2 0.0038 16.2 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4518) DUF4440 PF14534.1 CAR29236.1 - 0.035 14.2 0.0 0.047 13.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Sec3_C PF09763.4 CAR29237.1 - 3.5e-146 488.2 12.7 3.5e-146 488.2 8.8 2.2 2 0 0 2 2 2 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 CAR29237.1 - 1e-26 92.5 0.5 2.4e-26 91.3 0.3 1.7 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.7 CAR29237.1 - 8e-08 31.2 3.3 8e-08 31.2 2.3 2.3 2 0 0 2 2 2 1 Vps52 / Sac2 family Med15 PF09606.5 CAR29237.1 - 1.8 6.6 57.5 3.3 5.8 39.8 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Helicase_C PF00271.26 CAR29238.1 - 8.3e-21 73.6 0.1 3.6e-20 71.5 0.1 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAR29238.1 - 1.7e-19 69.9 0.3 1.1e-18 67.3 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 CAR29238.1 - 1.7e-18 67.0 0.0 1.7e-18 67.0 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CAR29238.1 - 0.045 13.8 0.0 0.75 9.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain EF-hand_4 PF12763.2 CAR29239.1 - 8.1e-27 92.9 0.1 1.6e-13 50.3 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 CAR29239.1 - 5.2e-08 32.9 0.0 0.00042 20.3 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair DUF1720 PF08226.6 CAR29239.1 - 1.2e-07 31.6 79.4 1.6e-05 24.8 32.1 13.6 3 2 4 7 7 7 3 Domain of unknown function (DUF1720) EF-hand_1 PF00036.27 CAR29239.1 - 1.9e-06 26.7 0.0 0.021 14.0 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 CAR29239.1 - 0.00027 20.5 0.2 3.3 7.8 0.1 3.7 3 0 0 3 3 3 2 EF-hand domain RRM_1 PF00076.17 CAR29240.1 - 1.3e-18 66.4 0.0 2.4e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR29240.1 - 3.6e-13 49.2 0.0 5.3e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR29240.1 - 1.1e-07 31.5 0.0 2.1e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_6 PF03737.10 CAR29241.1 - 4.8e-34 117.4 0.0 6.8e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase Mannosyl_trans3 PF11051.3 CAR29242.1 - 3.5e-63 213.5 0.2 6.2e-63 212.6 0.0 1.5 2 0 0 2 2 2 1 Mannosyltransferase putative ChaB PF06150.7 CAR29242.1 - 0.081 12.7 0.1 0.38 10.5 0.0 2.1 2 0 0 2 2 2 0 ChaB bZIP_2 PF07716.10 CAR29243.1 - 8.2e-09 35.1 8.8 8.2e-09 35.1 6.1 2.4 1 1 1 2 2 2 1 Basic region leucine zipper DUF2201_N PF13203.1 CAR29243.1 - 0.056 12.6 6.4 0.07 12.2 4.5 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain CTP-dep_RFKase PF01982.11 CAR29243.1 - 0.07 12.7 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF120 bZIP_1 PF00170.16 CAR29243.1 - 0.082 12.8 19.3 0.082 12.8 11.1 2.5 2 1 0 2 2 2 0 bZIP transcription factor YadA_stalk PF05662.9 CAR29243.1 - 0.13 12.0 0.4 0.67 9.8 0.1 2.2 2 0 0 2 2 2 0 Coiled stalk of trimeric autotransporter adhesin DDHD PF02862.12 CAR29243.1 - 0.29 10.9 4.6 0.33 10.7 3.2 1.3 1 0 0 1 1 1 0 DDHD domain bZIP_Maf PF03131.12 CAR29243.1 - 2.1 8.6 13.1 0.09 13.0 3.7 2.2 1 1 1 2 2 2 0 bZIP Maf transcription factor BAF1_ABF1 PF04684.8 CAR29244.1 - 2.1e-05 23.5 13.7 2.1e-05 23.5 9.5 1.8 2 0 0 2 2 2 1 BAF1 / ABF1 chromatin reorganising factor DUF4557 PF15101.1 CAR29244.1 - 1.9 8.2 18.0 5.8 6.7 12.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Med15 PF09606.5 CAR29244.1 - 9.5 4.2 43.9 0.0079 14.4 19.0 2.5 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal BaxI_1 PF12811.2 CAR29244.1 - 9.8 5.2 6.3 14 4.7 4.4 1.2 1 0 0 1 1 1 0 Bax inhibitor 1 like Proteasome PF00227.21 CAR29245.1 - 2.6e-56 189.9 0.0 3.5e-56 189.5 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CAR29245.1 - 6.2e-13 47.8 0.1 1.2e-12 46.8 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature KN_motif PF12075.3 CAR29245.1 - 0.43 10.4 1.8 0.9 9.3 1.3 1.5 1 0 0 1 1 1 0 KN motif TOM13 PF08219.6 CAR29246.1 - 7.5e-24 83.3 0.0 8.4e-24 83.1 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 Rpr2 PF04032.11 CAR29247.1 - 2.2e-16 59.4 0.4 3.4e-16 58.8 0.3 1.2 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Fer2_BFD PF04324.10 CAR29247.1 - 0.17 11.9 1.2 2.1 8.4 0.0 2.1 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain LETM1 PF07766.8 CAR29249.1 - 1.5e-102 342.2 3.0 2.5e-102 341.5 2.1 1.3 1 0 0 1 1 1 1 LETM1-like protein bZIP_1 PF00170.16 CAR29250.1 - 2.7e-05 24.0 14.8 6e-05 22.9 9.3 2.1 1 1 1 2 2 2 1 bZIP transcription factor Hap4_Hap_bind PF10297.4 CAR29250.1 - 4.6e-05 23.1 6.3 0.00011 21.9 4.3 1.7 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_2 PF07716.10 CAR29250.1 - 0.0042 16.8 12.6 0.08 12.7 5.9 2.4 2 0 0 2 2 2 1 Basic region leucine zipper FlaC_arch PF05377.6 CAR29250.1 - 0.046 13.6 0.6 0.96 9.3 0.4 2.5 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) Spc24 PF08286.6 CAR29250.1 - 0.071 12.8 3.2 0.092 12.4 1.1 2.0 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 CR6_interact PF10147.4 CAR29250.1 - 0.24 10.7 8.7 0.51 9.6 6.0 1.5 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Cluap1 PF10234.4 CAR29250.1 - 1 8.4 8.2 0.21 10.7 3.2 1.6 2 0 0 2 2 2 0 Clusterin-associated protein-1 Cortex-I_coil PF09304.5 CAR29250.1 - 1.4 9.0 13.7 0.36 10.8 6.1 2.4 3 0 0 3 3 3 0 Cortexillin I, coiled coil bZIP_Maf PF03131.12 CAR29250.1 - 2.1 8.7 12.6 0.47 10.7 6.0 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor IncA PF04156.9 CAR29250.1 - 2.9 7.4 11.8 2.1 7.9 5.2 2.2 2 0 0 2 2 2 0 IncA protein DUF4544 PF15077.1 CAR29250.1 - 9.6 5.6 7.6 37 3.7 0.7 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4544) Glyco_hydro_72 PF03198.9 CAR29251.1 - 4.8e-142 472.5 8.0 6.3e-142 472.1 5.6 1.1 1 0 0 1 1 1 1 Glucanosyltransferase SUR7 PF06687.7 CAR29252.1 - 1.2e-14 54.4 19.2 1.6e-14 53.9 13.3 1.1 1 0 0 1 1 1 1 SUR7/PalI family SNARE PF05739.14 CAR29253.1 - 4.6e-17 61.4 1.8 4.6e-17 61.4 1.2 2.6 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 CAR29253.1 - 3.2e-07 30.4 0.5 3.2e-07 30.4 0.3 2.5 1 1 1 2 2 2 1 Syntaxin TMPIT PF07851.8 CAR29253.1 - 2.4 7.1 7.1 0.37 9.7 2.2 1.6 1 1 1 2 2 2 0 TMPIT-like protein Afi1 PF07792.7 CAR29254.1 - 4.2e-32 111.1 0.0 9.5e-32 110.0 0.0 1.6 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 CAR29254.1 - 4.2e-23 81.1 0.0 8.3e-23 80.2 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis TPP_enzyme_N PF02776.13 CAR29255.1 - 2e-29 102.2 0.0 3.2e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 CAR29255.1 - 2.1e-18 66.3 0.0 3.7e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 CAR29255.1 - 2.2e-15 56.5 0.0 5.2e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain UPF0302 PF08864.5 CAR29255.1 - 0.086 12.6 0.1 0.21 11.4 0.1 1.6 1 0 0 1 1 1 0 UPF0302 domain AIRC PF00731.15 CAR29256.1 - 1.1e-64 216.2 1.6 1.8e-64 215.5 1.1 1.4 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 CAR29256.1 - 7.6e-63 210.9 0.0 1.3e-62 210.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 CAR29256.1 - 4.7e-07 29.7 0.0 8.7e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain 2-Hacid_dh_C PF02826.14 CAR29256.1 - 3.7e-05 22.9 0.0 7.9e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CoA_binding_2 PF13380.1 CAR29256.1 - 0.0077 16.4 0.5 3.3 7.8 0.0 3.3 2 1 1 3 3 3 1 CoA binding domain Dala_Dala_lig_C PF07478.8 CAR29256.1 - 0.0085 15.4 0.0 0.038 13.3 0.0 2.1 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.12 CAR29256.1 - 0.0086 15.3 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Shikimate_DH PF01488.15 CAR29256.1 - 0.09 12.8 0.1 1.7 8.7 0.0 2.8 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Complex1_LYR PF05347.10 CAR29257.1 - 4.2e-14 52.0 0.2 5.3e-14 51.7 0.1 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CAR29257.1 - 2.9e-12 46.5 0.1 3.5e-12 46.3 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like RhoGAP PF00620.22 CAR29258.1 - 1.3e-45 154.7 0.9 2.4e-45 153.8 0.1 1.9 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 CAR29258.1 - 5.2e-12 45.6 27.7 4.6e-06 26.6 5.6 2.6 2 0 0 2 2 2 2 LIM domain HLH PF00010.21 CAR29259.1 - 2e-12 46.5 2.9 5.2e-12 45.2 2.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4363 PF14276.1 CAR29259.1 - 0.021 14.5 3.2 0.04 13.6 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Pkinase PF00069.20 CAR29260.1 - 9.8e-41 139.6 0.0 1.5e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR29260.1 - 8.2e-15 54.5 0.0 1.2e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR29260.1 - 0.0046 15.9 0.0 0.0074 15.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CAR29260.1 - 0.0068 15.4 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family AAA PF00004.24 CAR29261.1 - 5.3e-52 175.5 0.0 8e-44 149.0 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 CAR29261.1 - 1.8e-23 82.3 0.2 5.1e-23 80.9 0.1 1.9 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 CAR29261.1 - 6.1e-12 45.9 1.3 3.5e-05 23.8 0.0 3.6 3 1 1 4 4 3 2 AAA ATPase domain AAA_14 PF13173.1 CAR29261.1 - 2.8e-09 36.9 0.0 0.00049 19.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 CAR29261.1 - 1e-08 35.0 0.7 0.00013 21.6 0.1 3.5 3 0 0 3 3 3 2 NACHT domain AAA_17 PF13207.1 CAR29261.1 - 1.8e-08 35.2 0.0 0.0053 17.5 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 CAR29261.1 - 1.8e-08 34.5 0.3 0.002 18.2 0.0 3.6 3 1 0 3 3 2 2 AAA domain AAA_25 PF13481.1 CAR29261.1 - 5.6e-07 29.1 0.4 0.34 10.2 0.1 4.1 2 2 2 4 4 4 2 AAA domain AAA_5 PF07728.9 CAR29261.1 - 6.5e-07 29.1 0.2 0.056 13.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CAR29261.1 - 7e-07 29.2 0.3 0.0097 15.7 0.0 3.2 4 0 0 4 4 2 2 AAA domain IstB_IS21 PF01695.12 CAR29261.1 - 1.3e-06 27.9 0.0 0.015 14.7 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 CAR29261.1 - 8.7e-06 26.0 0.1 0.066 13.5 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_2 PF07724.9 CAR29261.1 - 9.1e-06 25.6 0.0 0.024 14.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) ABC_tran PF00005.22 CAR29261.1 - 1.2e-05 25.5 0.0 0.016 15.4 0.0 3.0 2 1 0 2 2 2 1 ABC transporter RuvB_N PF05496.7 CAR29261.1 - 1.3e-05 24.4 0.0 0.0032 16.5 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 CAR29261.1 - 2.2e-05 24.4 0.0 0.18 11.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 CAR29261.1 - 3.9e-05 23.4 0.0 0.024 14.3 0.0 3.3 2 1 1 3 3 3 1 Archaeal ATPase RNA_helicase PF00910.17 CAR29261.1 - 8.4e-05 22.7 0.0 0.77 9.9 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_19 PF13245.1 CAR29261.1 - 8.8e-05 22.1 0.0 0.55 10.0 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain NB-ARC PF00931.17 CAR29261.1 - 0.00039 19.3 0.0 0.44 9.3 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain SKI PF01202.17 CAR29261.1 - 0.00055 19.8 0.0 0.84 9.4 0.0 2.5 2 0 0 2 2 2 2 Shikimate kinase Rad17 PF03215.10 CAR29261.1 - 0.00084 18.1 0.1 0.07 11.8 0.1 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein UPF0079 PF02367.12 CAR29261.1 - 0.00093 18.8 0.3 0.23 11.1 0.1 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 CAR29261.1 - 0.0014 18.3 0.6 1.5 8.3 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.6 CAR29261.1 - 0.0014 18.2 0.0 0.36 10.4 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 CAR29261.1 - 0.0016 17.5 0.0 0.26 10.3 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin Bac_DnaA PF00308.13 CAR29261.1 - 0.0019 17.8 0.0 0.2 11.2 0.0 2.9 2 0 0 2 2 2 1 Bacterial dnaA protein KaiC PF06745.8 CAR29261.1 - 0.0023 17.0 0.0 2.1 7.4 0.0 2.5 2 0 0 2 2 2 2 KaiC T2SE PF00437.15 CAR29261.1 - 0.0025 16.7 0.0 0.044 12.6 0.1 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Viral_helicase1 PF01443.13 CAR29261.1 - 0.0028 17.2 0.0 2.1 7.7 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Vps4_C PF09336.5 CAR29261.1 - 0.0075 16.1 0.1 0.032 14.1 0.0 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain KAP_NTPase PF07693.9 CAR29261.1 - 0.0078 15.2 0.0 0.056 12.4 0.0 2.3 3 0 0 3 3 2 1 KAP family P-loop domain DUF2075 PF09848.4 CAR29261.1 - 0.011 14.7 0.0 4.3 6.2 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TIP49 PF06068.8 CAR29261.1 - 0.012 14.3 0.0 0.12 11.0 0.0 2.2 2 0 0 2 2 2 0 TIP49 C-terminus PduV-EutP PF10662.4 CAR29261.1 - 0.013 15.0 0.4 0.35 10.3 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activat PF00158.21 CAR29261.1 - 0.017 14.6 0.0 5.8 6.3 0.0 2.8 2 1 0 2 2 2 0 Sigma-54 interaction domain MobB PF03205.9 CAR29261.1 - 0.025 14.2 0.1 0.13 11.9 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 CAR29261.1 - 0.027 13.6 0.1 0.079 12.1 0.0 1.8 2 0 0 2 2 1 0 Protein of unknown function, DUF258 ATP-synt_ab PF00006.20 CAR29261.1 - 0.032 13.7 0.0 2.1 7.8 0.0 2.7 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.1 CAR29261.1 - 0.032 13.7 0.4 1.1 8.7 0.0 2.7 3 0 0 3 3 2 0 AAA domain Cytidylate_kin2 PF13189.1 CAR29261.1 - 0.04 13.8 0.2 0.28 11.0 0.0 2.5 3 0 0 3 3 2 0 Cytidylate kinase-like family Mg_chelatase PF01078.16 CAR29261.1 - 0.046 12.8 0.1 0.82 8.7 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI CbiA PF01656.18 CAR29261.1 - 0.052 12.9 0.5 0.2 11.0 0.0 2.2 3 0 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 CAR29261.1 - 0.054 13.4 0.5 9.5 6.1 0.0 3.2 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.10 CAR29261.1 - 0.062 13.0 0.1 5.1 6.7 0.0 2.5 2 0 0 2 2 2 0 NTPase SRP54 PF00448.17 CAR29261.1 - 0.062 12.7 0.5 0.26 10.7 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_10 PF12846.2 CAR29261.1 - 0.075 12.4 0.3 0.76 9.1 0.0 2.6 3 0 0 3 3 3 0 AAA-like domain Clat_adaptor_s PF01217.15 CAR29262.1 - 7.3e-54 181.3 2.3 8.3e-54 181.1 1.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Thymidylate_kin PF02223.12 CAR29263.1 - 8.7e-39 132.8 0.0 1e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.1 CAR29263.1 - 0.015 15.1 0.1 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Kinase-PPPase PF03618.9 CAR29263.1 - 0.11 11.9 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Kinase/pyrophosphorylase DUF4588 PF15251.1 CAR29265.1 - 8.6e-07 29.1 5.2 9.7e-06 25.7 3.1 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) Zip PF02535.17 CAR29265.1 - 4.3 6.2 5.9 5 6.0 4.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SUR7 PF06687.7 CAR29266.1 - 1.4e-30 106.4 7.4 1.8e-30 106.1 5.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 CAR29266.1 - 0.011 15.5 4.2 0.02 14.8 2.9 1.5 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 GFO_IDH_MocA PF01408.17 CAR29267.1 - 1.6e-06 28.6 0.0 2.6e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 CAR29267.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain zf-HIT PF04438.11 CAR29268.1 - 3.5e-12 45.7 10.7 5.6e-12 45.0 7.4 1.4 1 0 0 1 1 1 1 HIT zinc finger YL1_C PF08265.6 CAR29268.1 - 0.024 14.1 0.1 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 YL1 nuclear protein C-terminal domain zf-Mss51 PF13824.1 CAR29268.1 - 0.033 14.0 6.5 0.064 13.1 4.5 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF1610 PF07754.6 CAR29268.1 - 0.11 12.5 2.8 0.17 12.0 0.6 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) zf-B_box PF00643.19 CAR29268.1 - 4.1 7.3 9.6 1.3 8.9 4.2 1.9 2 0 0 2 2 2 0 B-box zinc finger Suc_Fer-like PF06999.7 CAR29269.1 - 6.4e-36 124.5 0.0 9e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like CPSF_A PF03178.10 CAR29270.1 - 6.3e-59 199.6 0.2 5e-58 196.7 0.1 2.2 2 0 0 2 2 2 1 CPSF A subunit region BBS2_N PF14781.1 CAR29270.1 - 0.1 12.2 1.3 17 5.0 0.0 3.4 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal Gsf2 PF11055.3 CAR29271.1 - 6.8e-149 495.4 0.1 8.4e-149 495.1 0.1 1.0 1 0 0 1 1 1 1 Glucose signalling factor 2 LGFP PF08310.6 CAR29273.1 - 0.18 11.4 2.0 1.3 8.7 0.0 2.7 3 0 0 3 3 3 0 LGFP repeat DUF4367 PF14285.1 CAR29273.1 - 8 5.7 11.3 0.1 11.8 2.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4367) RRM_1 PF00076.17 CAR29275.1 - 3.6e-28 96.9 0.6 6.2e-17 60.9 0.1 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR29275.1 - 6.9e-24 83.6 0.3 7e-14 51.5 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR29275.1 - 3.7e-13 49.1 0.8 2.3e-06 27.3 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Apc1 PF12859.2 CAR29277.1 - 2e-16 60.1 0.1 2e-16 60.1 0.1 3.3 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 CAR29277.1 - 0.0052 16.9 8.4 7.1 7.0 0.8 5.2 5 0 0 5 5 5 3 Proteasome/cyclosome repeat PS_Dcarbxylase PF02666.10 CAR29278.1 - 1.5e-72 243.1 0.0 2.1e-72 242.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase dCMP_cyt_deam_1 PF00383.17 CAR29279.1 - 6e-26 90.0 2.0 1e-25 89.3 1.4 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region FAA_hydrolase PF01557.13 CAR29280.1 - 1.3e-45 155.4 0.0 1.6e-45 155.2 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family bZIP_1 PF00170.16 CAR29281.1 - 3.8e-06 26.7 4.0 1e-05 25.3 2.8 1.7 1 0 0 1 1 1 1 bZIP transcription factor Aft1_OSA PF11785.3 CAR29281.1 - 8.8e-06 26.1 2.2 8.8e-06 26.1 1.5 4.9 3 1 1 4 4 4 1 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.10 CAR29281.1 - 0.008 15.9 7.6 0.008 15.9 5.3 2.7 3 0 0 3 3 3 1 Basic region leucine zipper DNA_RNApol_7kD PF03604.8 CAR29282.1 - 1.9e-16 59.1 1.8 2.5e-16 58.8 1.3 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.14 CAR29282.1 - 0.0031 17.1 0.2 0.0033 17.0 0.1 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family DZR PF12773.2 CAR29282.1 - 0.0033 17.2 0.4 0.0044 16.7 0.3 1.2 1 0 0 1 1 1 1 Double zinc ribbon Prok-RING_1 PF14446.1 CAR29282.1 - 0.0066 16.1 0.6 0.0087 15.7 0.4 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 TFIIS_C PF01096.13 CAR29282.1 - 0.0097 15.5 2.5 2.4 7.8 0.2 2.4 2 1 0 2 2 2 2 Transcription factor S-II (TFIIS) FYDLN_acid PF09538.5 CAR29282.1 - 0.028 15.0 0.3 0.033 14.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) NCD3G PF07562.9 CAR29282.1 - 0.033 13.9 0.2 0.039 13.6 0.2 1.2 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR C1_1 PF00130.17 CAR29282.1 - 0.046 13.4 0.4 0.064 12.9 0.3 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) A2L_zn_ribbon PF08792.5 CAR29282.1 - 0.06 12.8 0.9 0.94 9.0 0.0 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain DUF4428 PF14471.1 CAR29282.1 - 0.062 13.0 1.4 1.4 8.7 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) DUF951 PF06107.6 CAR29282.1 - 0.064 12.7 1.5 1.5 8.3 0.3 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF951) FYVE_2 PF02318.11 CAR29282.1 - 0.075 12.9 0.4 0.082 12.8 0.2 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger DUF2318 PF10080.4 CAR29282.1 - 0.085 12.6 0.1 0.096 12.4 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) DUF2197 PF09963.4 CAR29282.1 - 0.086 12.8 2.4 6.8 6.7 0.1 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) Zn_ribbon_recom PF13408.1 CAR29282.1 - 0.21 11.8 3.2 3.4 8.0 0.5 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Ribosomal_L40e PF01020.12 CAR29282.1 - 0.31 10.6 2.7 0.41 10.2 1.9 1.2 1 0 0 1 1 1 0 Ribosomal L40e family Zn-ribbon_8 PF09723.5 CAR29282.1 - 0.35 10.8 3.4 1.2 9.2 2.3 1.8 1 1 0 1 1 1 0 Zinc ribbon domain DUF2296 PF10058.4 CAR29282.1 - 0.38 10.5 1.9 0.75 9.5 0.1 1.9 1 1 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) Zn_Tnp_IS1595 PF12760.2 CAR29282.1 - 0.4 10.5 2.9 1.6 8.6 2.3 1.7 1 1 1 2 2 2 0 Transposase zinc-ribbon domain TF_Zn_Ribbon PF08271.7 CAR29282.1 - 0.62 9.4 2.5 7.1 6.0 2.0 2.0 1 1 1 2 2 2 0 TFIIB zinc-binding zinc_ribbon_5 PF13719.1 CAR29282.1 - 0.99 9.0 3.3 6.6 6.4 2.3 2.2 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CAR29282.1 - 1 9.1 3.3 8.4 6.1 2.4 2.3 2 1 0 2 2 1 0 zinc-ribbon domain Ribosomal_L44 PF00935.14 CAR29282.1 - 1.6 8.7 4.5 10 6.1 0.5 2.1 1 1 1 2 2 2 0 Ribosomal protein L44 Nudix_N_2 PF14803.1 CAR29286.1 - 0.43 10.3 2.2 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Nudix N-terminal GTP_EFTU PF00009.22 CAR29287.1 - 1.2e-52 178.1 0.0 1.9e-52 177.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 CAR29287.1 - 1.8e-14 53.3 0.0 5.5e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CAR29287.1 - 9.6e-12 44.8 0.0 2.5e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 CAR29287.1 - 1.3e-09 37.7 0.1 4.7e-08 32.7 0.0 2.5 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_IV PF03764.13 CAR29287.1 - 7.4e-07 28.7 0.0 3.3e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 CAR29287.1 - 0.0015 18.5 0.0 0.0035 17.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Chs3p PF12271.3 CAR29288.1 - 5.1e-95 317.8 19.5 1.2e-94 316.6 13.5 1.5 1 1 0 1 1 1 1 Chitin synthase III catalytic subunit DUF2583 PF10762.4 CAR29288.1 - 0.59 10.2 10.2 0.5 10.5 0.8 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2583) Ribosomal_L44 PF00935.14 CAR29289.1 - 1.5e-33 114.5 11.7 2.4e-33 113.9 8.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Pkinase PF00069.20 CAR29290.1 - 3.6e-58 196.7 0.3 1.1e-39 136.1 0.1 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAR29290.1 - 1.4e-26 93.1 0.4 2.7e-20 72.5 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 CAR29290.1 - 0.0043 17.5 0.2 0.014 15.9 0.1 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Seadorna_VP7 PF07387.6 CAR29290.1 - 0.047 12.5 0.0 0.076 11.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 CAR29290.1 - 0.085 11.6 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF4407 PF14362.1 CAR29290.1 - 1.5 7.7 32.7 2.9 6.7 17.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Far-17a_AIG1 PF04750.9 CAR29291.1 - 5.1e-15 55.1 4.8 2.1e-11 43.3 2.2 2.0 2 0 0 2 2 2 2 FAR-17a/AIG1-like protein MscS_TM PF12794.2 CAR29291.1 - 0.0091 14.6 0.3 0.0091 14.6 0.2 2.4 1 1 1 2 2 2 1 Mechanosensitive ion channel inner membrane domain 1 DUF106 PF01956.11 CAR29291.1 - 0.16 11.5 1.0 0.31 10.5 0.6 1.5 1 1 0 1 1 1 0 Integral membrane protein DUF106 DUF2427 PF10348.4 CAR29291.1 - 4.9 6.7 6.4 6.5 6.3 0.4 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF2427) Asparaginase PF00710.15 CAR29292.1 - 8.5e-14 51.1 3.5 2.8e-13 49.4 1.5 2.3 1 1 0 1 1 1 1 Asparaginase Ammonium_transp PF00909.16 CAR29293.1 - 5.5e-125 416.9 28.6 6.3e-125 416.7 19.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF3185 PF11381.3 CAR29293.1 - 0.026 14.3 7.1 1.1 9.0 0.1 4.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) Inhibitor_I9 PF05922.11 CAR29294.1 - 0.00054 20.4 0.1 0.0034 17.9 0.1 2.0 1 1 0 1 1 1 1 Peptidase inhibitor I9 FliW PF02623.10 CAR29294.1 - 0.05 13.1 0.0 0.061 12.8 0.0 1.2 1 0 0 1 1 1 0 FliW protein Prefoldin_2 PF01920.15 CAR29295.1 - 1.9e-22 79.0 12.4 2.2e-22 78.7 8.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit DivIC PF04977.10 CAR29295.1 - 0.0084 15.5 1.7 0.0084 15.5 1.2 2.1 1 1 1 2 2 2 1 Septum formation initiator PspA_IM30 PF04012.7 CAR29295.1 - 0.017 14.4 1.0 0.017 14.4 0.7 1.8 2 0 0 2 2 2 0 PspA/IM30 family IFT46_B_C PF12317.3 CAR29295.1 - 0.023 14.0 0.6 0.032 13.6 0.2 1.4 1 1 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal DUF1949 PF09186.6 CAR29295.1 - 0.062 12.9 1.2 0.14 11.7 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1949) HemX PF04375.9 CAR29295.1 - 0.071 11.6 3.2 0.084 11.4 2.2 1.1 1 0 0 1 1 1 0 HemX TPR_MLP1_2 PF07926.7 CAR29295.1 - 0.12 12.1 7.0 0.17 11.6 4.8 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.14 CAR29295.1 - 0.13 10.1 4.4 0.22 9.3 3.0 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family PspB PF06667.7 CAR29295.1 - 0.24 11.3 2.5 1.6 8.6 0.1 2.3 2 0 0 2 2 2 0 Phage shock protein B Seryl_tRNA_N PF02403.17 CAR29295.1 - 0.25 11.3 8.6 0.48 10.4 1.0 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4140 PF13600.1 CAR29295.1 - 1.4 9.4 6.3 2.3 8.6 3.5 1.9 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF16 PF01519.11 CAR29295.1 - 2 8.7 10.0 3.8 7.8 7.0 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 Tropomyosin_1 PF12718.2 CAR29295.1 - 2.7 7.8 12.5 0.078 12.8 2.6 2.0 1 1 0 1 1 1 0 Tropomyosin like Aminotran_1_2 PF00155.16 CAR29296.1 - 4.7e-16 58.6 0.0 1.2e-15 57.4 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CAR29296.1 - 0.023 13.8 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_MocR PF12897.2 CAR29296.1 - 0.15 10.6 0.0 0.26 9.7 0.0 1.4 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase A_deaminase PF00962.17 CAR29298.1 - 6.6e-88 294.7 0.0 7.5e-88 294.6 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Ectatomin PF06457.6 CAR29298.1 - 0.23 11.1 0.6 22 4.8 0.1 2.4 2 0 0 2 2 2 0 Ectatomin Pkinase PF00069.20 CAR29299.1 - 2e-31 109.1 0.0 3.4e-31 108.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR29299.1 - 3.4e-12 45.9 0.0 6.1e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CAR29299.1 - 0.00037 19.6 0.0 0.0007 18.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CAR29299.1 - 0.00061 19.5 0.1 0.05 13.3 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family zf-AN1 PF01428.11 CAR29300.1 - 5.6e-11 42.1 13.8 9.1e-11 41.4 9.5 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger WLM PF08325.5 CAR29301.1 - 1.2e-54 185.0 0.0 1.4e-54 184.8 0.0 1.1 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 CAR29301.1 - 0.0077 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF45 INSIG PF07281.7 CAR29302.1 - 3.8e-12 45.9 5.0 9e-12 44.7 3.5 1.7 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) BTP PF05232.7 CAR29302.1 - 0.05 13.3 2.0 0.062 13.0 0.1 2.1 2 0 0 2 2 2 0 Bacterial Transmembrane Pair family DUF360 PF04020.8 CAR29302.1 - 0.059 13.7 0.8 0.059 13.7 0.6 1.9 2 0 0 2 2 2 0 Membrane protein of unknown function VIT1 PF01988.14 CAR29302.1 - 0.25 10.8 3.2 0.58 9.6 1.6 2.1 1 1 0 1 1 1 0 VIT family Endosulfine PF04667.12 CAR29303.1 - 1e-31 108.7 0.1 1.3e-31 108.3 0.1 1.1 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Toxin_54 PF15533.1 CAR29303.1 - 0.13 12.4 0.8 0.65 10.2 0.5 2.0 1 1 0 1 1 1 0 Putative toxin 54 Peptidase_M14 PF00246.19 CAR29304.1 - 1.5e-69 234.7 0.1 1.8e-69 234.4 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Pga1 PF10333.4 CAR29305.1 - 6.4e-57 192.1 1.0 7.5e-57 191.8 0.7 1.0 1 0 0 1 1 1 1 GPI-Mannosyltransferase II co-activator Proteasom_Rpn13 PF04683.8 CAR29305.1 - 0.027 14.5 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 Proteasome complex subunit Rpn13 ubiquitin receptor Arginase PF00491.16 CAR29307.1 - 3.8e-88 295.3 0.1 4.4e-88 295.1 0.1 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 CAR29307.1 - 0.012 15.8 1.2 0.021 15.0 0.8 1.5 1 1 0 1 1 1 0 UPF0489 domain DUF2009 PF09418.5 CAR29309.1 - 3.2e-224 744.8 2.8 3.8e-224 744.6 1.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.19 CAR29309.1 - 3.9e-06 26.6 9.9 9.3e-06 25.4 6.9 1.7 1 0 0 1 1 1 1 B-box zinc finger IBR PF01485.16 CAR29309.1 - 0.22 11.4 5.9 0.58 10.0 4.1 1.7 1 0 0 1 1 1 0 IBR domain Actin PF00022.14 CAR29310.1 - 1.3e-115 386.0 0.0 1.4e-115 385.8 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CAR29310.1 - 0.13 10.8 0.0 0.55 8.7 0.0 2.0 1 1 0 1 1 1 0 MreB/Mbl protein UPRTase PF14681.1 CAR29311.1 - 2.6e-76 255.4 0.0 3.2e-76 255.1 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 CAR29311.1 - 0.0023 17.6 0.0 0.0034 17.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 CAR29311.1 - 0.11 12.1 0.3 0.2 11.3 0.2 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) LSM PF01423.17 CAR29312.1 - 5.6e-19 67.4 0.2 7.3e-19 67.0 0.1 1.2 1 0 0 1 1 1 1 LSM domain CAP_GLY PF01302.20 CAR29313.1 - 2.2e-18 65.7 0.6 3.6e-18 65.0 0.4 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 CAR29313.1 - 8.8e-05 22.6 0.0 0.00019 21.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain PGA2 PF07543.7 CAR29314.1 - 1e-12 48.0 2.6 7.3e-06 25.8 0.0 2.1 1 1 1 2 2 2 2 Protein trafficking PGA2 E2_bind PF08825.5 CAR29314.1 - 0.045 13.5 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 E2 binding domain RNA_pol_3_Rpc31 PF11705.3 CAR29315.1 - 5.2e-67 226.1 17.7 5.8e-67 226.0 12.3 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 CDC45 PF02724.9 CAR29315.1 - 1.8 6.5 13.1 2.8 5.8 9.1 1.3 1 0 0 1 1 1 0 CDC45-like protein C2 PF00168.25 CAR29316.1 - 0.014 15.2 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 C2 domain Tho2 PF11262.3 CAR29317.1 - 1e-58 198.7 8.4 1e-58 198.7 5.8 3.8 3 1 0 3 3 3 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 CAR29317.1 - 7.7e-26 89.6 0.3 2e-25 88.3 0.2 1.8 1 0 0 1 1 1 1 Transcription- and export-related complex subunit SF3b10 PF07189.6 CAR29318.1 - 2e-23 82.0 1.0 2e-23 81.9 0.7 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) TnpV PF14198.1 CAR29318.1 - 0.13 12.1 0.4 0.16 11.8 0.2 1.2 1 0 0 1 1 1 0 Transposon-encoded protein TnpV Limkain-b1 PF11608.3 CAR29319.1 - 0.07 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 CAP_N PF01213.14 CAR29320.1 - 2.9e-100 335.5 0.5 4.2e-100 335.0 0.3 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 CAR29320.1 - 6.1e-58 194.6 0.3 8.6e-58 194.1 0.2 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal S4 PF01479.20 CAR29321.1 - 5.5e-15 54.5 0.0 1e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 CAR29321.1 - 0.026 14.0 0.0 0.064 12.8 0.0 1.6 1 0 0 1 1 1 0 S4 domain Eaf7 PF07904.8 CAR29322.1 - 1.5e-30 105.0 0.7 1.5e-30 105.0 0.5 2.2 3 0 0 3 3 3 1 Chromatin modification-related protein EAF7 YL1 PF05764.8 CAR29322.1 - 3.6 7.1 36.1 0.2 11.2 11.2 2.2 1 1 1 2 2 2 0 YL1 nuclear protein FKBP_C PF00254.23 CAR29323.1 - 8.7e-33 112.2 0.0 1e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ADH_zinc_N PF00107.21 CAR29324.1 - 3.2e-12 46.1 0.0 5.1e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CAR29324.1 - 1.3e-08 34.5 0.1 3.7e-07 29.8 0.1 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain PIR PF00399.14 CAR29325.1 - 1.4e-06 27.4 3.0 7.8e-06 25.0 2.1 2.3 1 0 0 1 1 1 1 Yeast PIR protein repeat BASP1 PF05466.7 CAR29325.1 - 0.17 11.6 16.3 0.19 11.5 11.3 1.0 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) DEC-1_N PF04625.8 CAR29325.1 - 5.2 5.6 10.8 5.5 5.5 7.5 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Med3 PF11593.3 CAR29325.1 - 9.1 5.4 13.2 10 5.2 9.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MdoG PF04349.7 CAR29326.1 - 5.5e-09 34.8 0.0 3.1 5.9 0.0 5.0 5 0 0 5 5 5 4 Periplasmic glucan biosynthesis protein, MdoG FliG_N PF14842.1 CAR29326.1 - 1.4e-08 34.7 0.0 5.9 7.0 0.0 5.1 5 0 0 5 5 5 2 FliG N-terminal domain HsbA PF12296.3 CAR29326.1 - 3.4e-06 26.9 8.6 14 5.5 0.0 6.7 5 1 1 6 6 6 0 Hydrophobic surface binding protein A V-SNARE PF05008.10 CAR29326.1 - 4.1e-06 26.8 4.5 13 6.0 0.0 6.7 9 1 0 9 9 9 0 Vesicle transport v-SNARE protein N-terminus DUF1640 PF07798.6 CAR29326.1 - 5.6e-05 23.2 0.0 13 5.7 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF1640) DUF4037 PF13228.1 CAR29326.1 - 0.00019 21.6 0.0 69 3.7 0.0 4.7 5 0 0 5 5 5 0 Domain of unknown function (DUF4037) Plasmod_dom_1 PF09715.5 CAR29326.1 - 0.00069 19.4 3.1 4.9 7.1 0.0 5.2 5 0 0 5 5 5 1 Plasmodium protein of unknown function (Plasmod_dom_1) Baculo_PEP_C PF04513.7 CAR29326.1 - 0.0012 18.6 16.6 3.1 7.6 2.5 5.9 4 2 2 6 6 6 1 Baculovirus polyhedron envelope protein, PEP, C terminus TAF4 PF05236.9 CAR29326.1 - 0.0043 16.3 0.0 12 5.1 0.0 3.9 4 0 0 4 4 4 0 Transcription initiation factor TFIID component TAF4 family ApbA_C PF08546.6 CAR29326.1 - 0.0057 16.6 0.0 38 4.2 0.0 4.1 4 0 0 4 4 4 0 Ketopantoate reductase PanE/ApbA C terminal Polysacc_synt PF01943.12 CAR29326.1 - 0.025 13.8 0.1 1.2e+02 1.7 0.0 4.3 4 0 0 4 4 4 0 Polysaccharide biosynthesis protein DXP_synthase_N PF13292.1 CAR29326.1 - 0.036 13.0 0.0 21 3.9 0.0 3.9 5 0 0 5 5 5 0 1-deoxy-D-xylulose-5-phosphate synthase Arena_glycoprot PF00798.13 CAR29326.1 - 0.036 12.4 0.0 77 1.4 0.0 3.9 4 0 0 4 4 4 0 Arenavirus glycoprotein LEDGF PF11467.3 CAR29326.1 - 0.098 12.3 0.4 1.1e+02 2.6 0.0 4.2 5 0 0 5 5 5 0 Lens epithelium-derived growth factor (LEDGF) Sigma54_DBD PF04552.8 CAR29326.1 - 0.21 11.0 0.3 49 3.3 0.0 4.0 5 0 0 5 5 5 0 Sigma-54, DNA binding domain DASH_Dad1 PF08649.5 CAR29326.1 - 1.3 8.7 12.9 19 5.0 0.7 5.4 5 0 0 5 5 5 0 DASH complex subunit Dad1 CoatB PF10389.4 CAR29326.1 - 8.3 6.3 11.1 1.9e+02 1.9 0.1 5.1 5 0 0 5 5 5 0 Bacteriophage coat protein B FliC PF12445.3 CAR29327.1 - 0.0011 19.0 49.4 0.014 15.5 4.7 6.8 3 2 4 7 7 7 4 Flagellin protein Inhibitor_I78 PF11720.3 CAR29327.1 - 0.013 15.2 0.2 83 3.0 0.0 4.4 5 0 0 5 5 5 0 Peptidase inhibitor I78 family Phostensin_N PF13916.1 CAR29327.1 - 0.017 15.0 1.0 58 3.7 0.0 3.5 3 0 0 3 3 3 0 PP1-regulatory protein, Phostensin N-terminal DUF2140 PF09911.4 CAR29327.1 - 0.079 12.1 0.6 5 6.2 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2140) OstA PF03968.9 CAR29327.1 - 0.19 11.6 3.7 67 3.4 0.1 3.9 3 0 0 3 3 3 0 OstA-like protein Staphylcoagulse PF04022.7 CAR29327.1 - 0.69 9.3 47.2 4.9 6.6 0.1 11.4 12 0 0 12 12 12 0 Staphylocoagulase repeat SRF-TF PF00319.13 CAR29327.1 - 3.6 6.9 12.1 47 3.3 0.0 6.2 7 0 0 7 7 7 0 SRF-type transcription factor (DNA-binding and dimerisation domain) NDT80_PhoG PF05224.7 CAR29329.1 - 1.3e-62 211.1 0.0 2.3e-62 210.2 0.0 1.4 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family GNAT_acetyltr_2 PF13718.1 CAR29330.1 - 9.5e-81 269.8 0.0 1.9e-80 268.8 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 CAR29330.1 - 2.2e-65 219.5 0.1 1.2e-64 217.2 0.0 2.3 2 1 1 3 3 3 1 Helicase DUF1726 PF08351.6 CAR29330.1 - 1.4e-40 136.8 0.1 4.3e-40 135.2 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 CAR29330.1 - 1.1e-38 131.3 0.3 3.6e-38 129.7 0.2 1.9 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 CAR29330.1 - 0.08 13.1 0.0 0.49 10.5 0.0 2.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Tom22 PF04281.8 CAR29331.1 - 3.3e-52 175.6 0.5 3.7e-52 175.4 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 CDP-OH_P_transf PF01066.16 CAR29332.1 - 2.7e-13 50.0 0.1 2.7e-13 50.0 0.0 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF59 PF01883.14 CAR29333.1 - 8.5e-07 28.8 0.0 1.4e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF59 AAA_18 PF13238.1 CAR29334.1 - 1.5e-07 31.7 0.0 1.1e-06 29.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CAR29334.1 - 2.8e-06 28.1 0.0 7.3e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 CAR29334.1 - 5.5e-06 26.0 0.0 8.9e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CPT PF07931.7 CAR29334.1 - 0.00012 21.7 0.0 0.0011 18.5 0.0 2.2 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 CAR29334.1 - 0.0044 16.8 0.0 0.011 15.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CAR29334.1 - 0.091 13.0 0.1 0.16 12.2 0.1 1.4 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 CAR29334.1 - 0.093 12.6 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 CAR29334.1 - 0.098 11.8 0.2 0.57 9.3 0.0 1.9 1 1 1 2 2 2 0 Chromatin associated protein KTI12 DSPc PF00782.15 CAR29335.1 - 1.9e-10 40.4 0.0 3.8e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CAR29335.1 - 0.0041 16.5 0.0 0.0067 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CAR29335.1 - 0.019 15.0 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 CAR29335.1 - 0.027 14.7 0.0 0.05 13.8 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family AD PF09793.4 CAR29336.1 - 3.8e-27 93.9 0.1 7.2e-27 93.0 0.1 1.4 1 0 0 1 1 1 1 Anticodon-binding domain LSM14 PF12701.2 CAR29336.1 - 0.019 14.7 0.3 0.26 11.0 0.2 2.2 1 1 0 1 1 1 0 Scd6-like Sm domain DUF3402 PF11882.3 CAR29337.1 - 3.1e-81 273.5 8.0 3.1e-81 273.5 5.5 3.2 2 1 0 2 2 2 1 Domain of unknown function (DUF3402) N1221 PF07923.8 CAR29337.1 - 1.3e-79 267.1 3.2 1.3e-79 267.1 2.2 1.7 2 0 0 2 2 2 1 N1221-like protein IBV_3A PF03617.8 CAR29337.1 - 0.023 14.4 3.2 0.38 10.5 0.0 2.7 2 0 0 2 2 2 0 IBV 3A protein FerA PF08165.6 CAR29337.1 - 0.048 13.3 0.2 0.14 11.7 0.1 1.8 1 0 0 1 1 1 0 FerA (NUC095) domain Spc97_Spc98 PF04130.8 CAR29338.1 - 2.6e-66 224.0 23.6 4.8e-66 223.2 16.4 1.4 1 0 0 1 1 1 1 Spc97 / Spc98 family MFS_1 PF07690.11 CAR29339.1 - 1.2e-23 83.3 43.1 2.6e-23 82.3 29.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 CAR29339.1 - 7.2e-12 44.4 23.6 7.2e-12 44.4 16.3 1.9 1 1 1 2 2 2 1 MFS/sugar transport protein Sugar_tr PF00083.19 CAR29339.1 - 2e-07 29.9 23.4 9.8e-06 24.3 6.6 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 CAR29339.1 - 0.00013 21.6 0.3 0.00013 21.6 0.2 2.1 2 0 0 2 2 2 1 MFS_1 like family Gar1 PF04410.9 CAR29340.1 - 3.5e-46 156.4 0.7 3.5e-46 156.4 0.5 2.2 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region NTR2 PF15458.1 CAR29340.1 - 0.00031 20.0 3.1 0.00031 20.0 2.2 3.2 4 0 0 4 4 4 1 Nineteen complex-related protein 2 PP28 PF10252.4 CAR29340.1 - 6.3 6.8 11.8 0.048 13.6 2.2 1.9 2 0 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 MutS_V PF00488.16 CAR29341.1 - 6.2e-75 251.6 0.0 1.1e-74 250.8 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CAR29341.1 - 1.4e-32 113.1 3.7 3e-32 112.0 2.5 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 CAR29341.1 - 1.4e-24 86.3 0.0 3.4e-24 85.0 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 CAR29341.1 - 6.3e-11 42.4 0.0 8.9e-10 38.7 0.0 2.8 2 0 0 2 2 2 1 MutS domain II N-SET PF11764.3 CAR29342.1 - 2.5e-40 138.1 0.5 2.5e-40 138.1 0.4 3.0 4 0 0 4 4 4 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.23 CAR29342.1 - 2e-22 80.2 0.2 2e-22 80.2 0.1 4.1 4 2 0 4 4 4 1 SET domain SET_assoc PF11767.3 CAR29342.1 - 2e-19 68.6 0.0 4.9e-19 67.3 0.0 1.6 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated ORC6 PF05460.8 CAR29343.1 - 1.4e-87 294.1 6.9 1.6e-87 293.9 4.8 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) XAP5 PF04921.9 CAR29343.1 - 0.17 11.4 5.1 0.51 9.8 2.8 2.0 2 0 0 2 2 2 0 XAP5, circadian clock regulator Suf PF05843.9 CAR29343.1 - 0.17 11.5 6.0 0.27 10.9 4.1 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF1980 PF09323.5 CAR29343.1 - 0.23 11.1 0.1 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Roughex PF06020.6 CAR29343.1 - 0.35 9.5 5.2 0.54 8.8 3.6 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Ribosomal_L35p PF01632.14 CAR29344.1 - 1.2e-08 34.6 4.2 1.5e-08 34.4 2.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L35 TPR_11 PF13414.1 CAR29345.1 - 4.4e-32 109.5 28.1 2.7e-13 49.3 0.2 7.0 3 2 6 9 9 9 8 TPR repeat TPR_2 PF07719.12 CAR29345.1 - 2.9e-21 73.5 34.4 0.0011 18.6 0.5 11.3 9 2 2 11 11 11 6 Tetratricopeptide repeat TPR_1 PF00515.23 CAR29345.1 - 3.3e-20 70.7 41.2 4e-06 26.1 1.5 10.6 10 2 1 11 11 11 5 Tetratricopeptide repeat TPR_12 PF13424.1 CAR29345.1 - 7.2e-18 64.2 18.0 0.00023 21.0 0.0 7.4 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.1 CAR29345.1 - 7.4e-17 61.5 24.2 0.00082 19.9 0.3 6.6 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 CAR29345.1 - 4.6e-13 47.9 31.7 0.0044 16.7 0.2 8.7 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_17 PF13431.1 CAR29345.1 - 1e-12 47.1 13.3 0.0003 20.7 0.1 8.2 6 3 1 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 CAR29345.1 - 3.2e-11 42.8 11.9 0.42 11.3 0.0 8.8 5 4 4 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.1 CAR29345.1 - 4.3e-11 42.9 19.4 0.00078 19.7 0.7 6.2 4 2 3 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 CAR29345.1 - 1.6e-08 34.5 17.2 0.0035 17.4 2.1 4.3 3 1 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CAR29345.1 - 9.5e-06 25.3 0.0 6.1 6.7 0.0 5.0 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 CAR29345.1 - 0.00024 20.6 16.9 0.25 11.2 0.1 7.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_10 PF13374.1 CAR29345.1 - 0.016 15.0 6.7 41 4.3 0.0 6.1 8 0 0 8 8 8 0 Tetratricopeptide repeat Exonuc_VII_S PF02609.11 CAR29345.1 - 0.017 14.8 4.4 0.038 13.7 0.2 3.5 3 0 0 3 3 3 0 Exonuclease VII small subunit SPO22 PF08631.5 CAR29345.1 - 0.021 13.9 5.2 0.022 13.8 0.1 3.1 4 0 0 4 4 4 0 Meiosis protein SPO22/ZIP4 like TPR_20 PF14561.1 CAR29345.1 - 0.32 11.1 8.2 1 9.5 0.7 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat RPN7 PF10602.4 CAR29345.1 - 1.8 7.9 8.3 0.49 9.7 0.1 3.6 5 0 0 5 5 5 0 26S proteasome subunit RPN7 TPR_3 PF07720.7 CAR29345.1 - 2.3 8.0 25.2 0.05 13.4 1.7 6.1 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF1903 PF08991.5 CAR29346.1 - 1e-05 25.5 2.1 1.5e-05 25.0 1.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 CAR29346.1 - 0.00037 20.3 9.2 0.00059 19.6 6.3 1.3 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 CAR29346.1 - 0.072 13.1 2.8 0.098 12.7 1.9 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 UPF0203 PF05254.7 CAR29346.1 - 0.09 12.6 3.5 0.19 11.6 2.4 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) DAGK_cat PF00781.19 CAR29347.1 - 7.9e-09 35.0 0.0 2.1e-08 33.6 0.0 1.6 1 1 1 2 2 2 1 Diacylglycerol kinase catalytic domain YqzH PF14164.1 CAR29347.1 - 0.051 13.4 0.0 0.56 10.1 0.0 2.5 3 0 0 3 3 3 0 YqzH-like protein zf-primase PF09329.6 CAR29348.1 - 5.5e-15 54.6 1.0 9.5e-15 53.9 0.7 1.4 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.20 CAR29348.1 - 0.043 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain TPR_MLP1_2 PF07926.7 CAR29349.1 - 2.7e-22 78.9 28.8 2.7e-22 78.9 20.0 16.8 3 3 9 12 12 12 3 TPR/MLP1/MLP2-like protein ubiquitin PF00240.18 CAR29350.1 - 1.3e-34 117.3 0.9 1.7e-34 117.0 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 CAR29350.1 - 2.6e-31 106.9 10.1 4.2e-31 106.3 7.0 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 CAR29350.1 - 3.9e-20 71.3 0.7 6.5e-20 70.5 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CAR29350.1 - 7.1e-06 26.1 0.2 2.6e-05 24.4 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CAR29350.1 - 0.0001 22.0 0.0 0.00012 21.7 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CAR29350.1 - 0.0054 16.5 0.1 0.012 15.5 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CAR29350.1 - 0.012 15.7 0.1 0.013 15.7 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 CAR29350.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Fer2_3 PF13085.1 CAR29350.1 - 0.14 12.0 1.6 0.6 9.9 1.1 2.0 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Response_reg PF00072.19 CAR29351.1 - 1.5e-28 99.0 0.7 2.9e-28 98.0 0.5 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 CAR29351.1 - 2e-26 91.8 0.3 1e-20 73.5 0.0 2.6 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 CAR29351.1 - 2.2e-10 40.3 1.7 2.5e-10 40.2 0.1 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 CAR29351.1 - 0.0071 16.5 7.7 0.56 10.4 0.0 2.9 3 0 0 3 3 3 2 HAMP domain PTR2 PF00854.16 CAR29353.1 - 4.3e-60 203.4 9.6 5.4e-60 203.1 6.7 1.1 1 0 0 1 1 1 1 POT family MFS_1 PF07690.11 CAR29353.1 - 1.8e-09 36.8 23.8 1.4e-08 33.8 15.3 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Aa_trans PF01490.13 CAR29354.1 - 1.6e-25 89.5 32.2 1.7e-24 86.1 22.3 2.2 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Pantoate_ligase PF02569.10 CAR29355.1 - 1.9e-92 309.0 0.0 2.1e-92 308.8 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Acetyltransf_1 PF00583.19 CAR29356.1 - 1.2e-09 37.9 0.0 1.8e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CAR29356.1 - 1.3e-08 34.8 0.0 2.2e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CAR29356.1 - 0.00037 20.4 0.0 0.00068 19.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CAR29356.1 - 0.00052 19.9 0.0 0.00077 19.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CAR29356.1 - 0.018 14.8 0.0 0.07 12.9 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 CAR29356.1 - 0.074 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_10 PF13673.1 CAR29356.1 - 0.15 12.1 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ARGLU PF15346.1 CAR29357.1 - 0.09 12.5 4.2 0.1 12.3 2.9 1.0 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 UCH PF00443.24 CAR29358.1 - 8.3e-69 231.6 0.5 1.8e-68 230.6 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CAR29358.1 - 3.6e-29 102.1 0.0 7.6e-29 101.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 CAR29358.1 - 9.4e-06 25.9 0.0 2.8e-05 24.4 0.0 1.9 1 1 0 1 1 1 1 Rhodanese-like domain Zn-ribbon_8 PF09723.5 CAR29358.1 - 0.0065 16.4 2.0 0.43 10.5 0.6 2.7 2 0 0 2 2 2 1 Zinc ribbon domain zf-MIZ PF02891.15 CAR29358.1 - 0.032 13.7 4.6 0.079 12.4 3.2 1.7 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger DUF4428 PF14471.1 CAR29358.1 - 0.041 13.6 1.6 0.14 11.8 1.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) CW_binding_1 PF01473.15 CAR29358.1 - 0.41 10.8 4.6 1.6 9.0 3.2 2.0 1 0 0 1 1 1 0 Putative cell wall binding repeat BSD PF03909.12 CAR29359.1 - 4.6e-14 51.8 0.5 1.7e-13 50.1 0.1 2.1 2 0 0 2 2 2 1 BSD domain Y_phosphatase2 PF03162.8 CAR29360.1 - 5.2e-54 182.0 1.2 7.5e-54 181.5 0.8 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family PH_10 PF15411.1 CAR29360.1 - 0.08 13.1 0.7 0.15 12.2 0.5 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain Asp_protease PF09668.5 CAR29361.1 - 2.3e-52 175.7 0.1 3.3e-52 175.2 0.1 1.2 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 CAR29361.1 - 1.4e-10 41.4 0.1 4.3e-10 39.9 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CAR29361.1 - 1.3e-08 34.5 0.0 3.6e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 CAR29361.1 - 4e-08 33.0 0.1 8.9e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA PF00627.26 CAR29361.1 - 1.4e-07 31.1 0.1 4e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain RVP_2 PF08284.6 CAR29361.1 - 3.4e-05 23.7 0.0 6.1e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease HhH-GPD PF00730.20 CAR29362.1 - 4e-11 43.1 0.0 6.8e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein bZIP_2 PF07716.10 CAR29362.1 - 0.2 11.4 1.9 0.52 10.1 1.3 1.6 1 0 0 1 1 1 0 Basic region leucine zipper COX15-CtaA PF02628.10 CAR29363.1 - 1.2e-102 342.8 1.6 1.4e-102 342.5 1.1 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF4149 PF13664.1 CAR29363.1 - 0.45 10.6 5.2 2.3 8.3 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) DUF747 PF05346.6 CAR29364.1 - 4.4e-89 298.7 21.2 6.2e-89 298.3 14.7 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family DUF2200 PF09966.4 CAR29364.1 - 0.017 14.9 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2200) RPAP2_Rtr1 PF04181.8 CAR29365.1 - 9e-20 70.5 0.3 1.7e-19 69.6 0.2 1.5 1 0 0 1 1 1 1 Rtr1/RPAP2 family TraB PF01963.12 CAR29365.1 - 0.0071 15.8 0.0 0.05 13.0 0.0 1.9 2 0 0 2 2 2 1 TraB family Argos PF11581.3 CAR29365.1 - 0.067 13.1 0.8 0.18 11.7 0.0 1.9 1 1 1 2 2 2 0 Antagonist of EGFR signalling, Argos DUF4291 PF14124.1 CAR29366.1 - 0.0097 15.5 1.5 0.028 14.0 1.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) Complex1_LYR PF05347.10 CAR29366.1 - 0.027 14.2 1.3 0.027 14.2 0.9 3.1 3 0 0 3 3 3 0 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CAR29366.1 - 2.2 8.5 5.4 2.9 8.1 0.2 3.3 2 1 0 2 2 2 0 Complex1_LYR-like Ras PF00071.17 CAR29367.1 - 4.2e-50 169.3 0.0 5.2e-50 168.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR29367.1 - 9.1e-18 64.8 0.0 1.6e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAR29367.1 - 4.7e-08 32.4 0.1 5.8e-08 32.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CAR29367.1 - 3.2e-06 26.7 0.0 5.9e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CAR29367.1 - 0.006 16.5 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 CAR29367.1 - 0.032 12.9 3.3 5.2 5.6 0.0 3.1 2 1 1 3 3 3 0 G-protein alpha subunit tRNA_bind PF01588.15 CAR29368.1 - 8e-17 60.8 0.4 1.3e-16 60.1 0.3 1.3 1 0 0 1 1 1 1 Putative tRNA binding domain PITH PF06201.8 CAR29369.1 - 1.6e-37 128.5 0.0 2.2e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 PITH domain ALAD PF00490.16 CAR29370.1 - 1.1e-115 386.0 0.0 1.3e-115 385.7 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase PALP PF00291.20 CAR29371.1 - 4.4e-55 187.0 0.0 5.6e-55 186.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 CAR29371.1 - 2.5e-13 49.5 0.1 1.1e-09 37.9 0.1 2.5 2 0 0 2 2 2 2 CBS domain GHMP_kinases_C PF08544.8 CAR29371.1 - 0.11 12.7 0.0 0.62 10.3 0.0 2.2 2 0 0 2 2 2 0 GHMP kinases C terminal ComZ PF10815.3 CAR29372.1 - 0.001 18.8 0.2 0.0018 18.0 0.2 1.4 1 0 0 1 1 1 1 ComZ AA_permease PF00324.16 CAR29373.1 - 7.6e-116 387.2 36.6 8.7e-116 387.0 25.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CAR29373.1 - 1.1e-39 136.2 45.2 1.4e-39 135.8 31.3 1.1 1 0 0 1 1 1 1 Amino acid permease TFIIS_M PF07500.9 CAR29374.1 - 8.2e-29 100.0 2.9 8.2e-29 100.0 2.0 1.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 CAR29374.1 - 1.3e-17 63.0 6.3 3e-17 61.9 4.4 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 CAR29374.1 - 5.7e-14 51.3 2.0 1.3e-13 50.1 1.4 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Milton PF12448.3 CAR29374.1 - 0.019 15.1 3.9 0.03 14.5 2.5 1.4 1 1 0 1 1 1 0 Kinesin associated protein Ribosomal_S27 PF01599.14 CAR29374.1 - 0.23 11.3 2.6 1.9 8.3 0.1 2.4 2 0 0 2 2 2 0 Ribosomal protein S27a Zn_Tnp_IS1595 PF12760.2 CAR29374.1 - 1.4 8.8 5.4 4.9 7.0 3.8 1.8 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Phyto_Pns9_10 PF05878.6 CAR29374.1 - 1.7 7.5 6.1 0.28 10.1 1.9 1.5 2 0 0 2 2 2 0 Phytoreovirus nonstructural protein Pns9/Pns10 RRM_1 PF00076.17 CAR29375.1 - 5.7e-21 73.9 0.0 9.6e-21 73.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR29375.1 - 9.9e-14 51.0 0.0 2.7e-13 49.6 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR29375.1 - 9.7e-11 41.3 0.0 1.5e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 CAR29375.1 - 2.2e-07 30.0 0.2 4.1e-07 29.1 0.2 1.4 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal CSTF2_hinge PF14327.1 CAR29375.1 - 8.7e-05 22.5 0.8 0.00016 21.6 0.0 1.8 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF2_hinge PF14327.1 CAR29376.1 - 7e-24 83.7 5.6 7e-24 83.7 3.9 2.6 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 PEMT PF04191.8 CAR29377.1 - 3.4e-57 191.0 11.7 9.5e-34 115.6 0.6 3.2 3 0 0 3 3 3 2 Phospholipid methyltransferase SelP_N PF04592.9 CAR29377.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region ICMT PF04140.9 CAR29377.1 - 1.6 8.9 7.0 1.9 8.7 0.2 3.2 3 1 0 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family RNase_PH PF01138.16 CAR29378.1 - 2.6e-17 63.3 0.2 5.1e-17 62.4 0.1 1.4 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Arrestin_N PF00339.24 CAR29379.1 - 2e-18 66.6 0.0 1.7e-17 63.5 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CAR29379.1 - 2.1e-08 34.3 4.1 2.1e-06 27.8 0.0 2.7 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Molydop_binding PF01568.16 CAR29379.1 - 0.016 15.0 0.0 0.047 13.5 0.0 1.8 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain RRM_1 PF00076.17 CAR29380.1 - 3.5e-43 145.0 1.3 6e-21 73.8 0.0 3.2 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR29380.1 - 1.8e-30 104.7 0.0 4.3e-16 58.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR29380.1 - 4.7e-21 74.3 0.0 5.5e-12 45.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Herpes_BLRF2 PF05812.7 CAR29382.1 - 0.0088 15.8 3.5 0.033 14.0 0.2 2.3 1 1 1 2 2 2 1 Herpesvirus BLRF2 protein HALZ PF02183.13 CAR29382.1 - 0.0098 15.5 1.6 0.013 15.1 0.3 1.7 2 0 0 2 2 2 1 Homeobox associated leucine zipper TFIIE_beta PF02186.10 CAR29382.1 - 0.082 12.9 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 TFIIE beta subunit core domain Ferric_reduct PF01794.14 CAR29383.1 - 2.9e-21 75.8 8.4 2.9e-21 75.8 5.8 3.2 4 0 0 4 4 4 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 CAR29383.1 - 2.8e-19 68.9 0.0 5.4e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 CAR29383.1 - 2.8e-18 66.2 0.0 4.5e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain MFS_1 PF07690.11 CAR29384.1 - 1e-15 57.3 31.4 2.4e-15 56.1 21.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 CAR29384.1 - 1.9e-06 26.4 13.4 4e-06 25.3 9.3 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2530 PF10745.4 CAR29384.1 - 0.043 13.8 0.6 0.19 11.7 0.4 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) Metallophos PF00149.23 CAR29385.1 - 1.7e-07 30.8 8.4 6.2e-06 25.7 5.8 3.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CAR29385.1 - 0.00023 21.0 0.0 0.0039 17.0 0.0 2.4 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Cu-oxidase_2 PF07731.9 CAR29386.1 - 5e-38 129.7 8.7 5.6e-35 119.8 0.6 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 CAR29386.1 - 1.7e-36 124.5 0.4 1.7e-36 124.5 0.2 3.3 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.17 CAR29386.1 - 1.4e-31 109.5 3.2 9.5e-31 106.8 0.1 3.1 4 0 0 4 4 4 1 Multicopper oxidase Phosphoesterase PF04185.9 CAR29387.1 - 2.8e-37 128.7 5.1 9.1e-36 123.8 3.0 2.7 1 1 1 2 2 2 2 Phosphoesterase family SET PF00856.23 CAR29388.1 - 6e-09 36.4 0.5 2.9e-08 34.1 0.0 2.4 2 1 0 2 2 2 1 SET domain Cofilin_ADF PF00241.15 CAR29389.1 - 4.6e-44 149.3 0.2 5.1e-44 149.2 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein CBM_4_9 PF02018.12 CAR29389.1 - 0.0039 17.1 0.3 0.0095 15.9 0.1 1.6 2 0 0 2 2 2 1 Carbohydrate binding domain Phage_gp53 PF11246.3 CAR29389.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Base plate wedge protein 53 AA_permease_2 PF13520.1 CAR29392.1 - 1.9e-57 194.7 38.1 2.6e-57 194.2 26.4 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CAR29392.1 - 3.1e-13 48.9 29.9 4.9e-13 48.2 20.7 1.2 1 1 0 1 1 1 1 Amino acid permease PalH PF08733.5 CAR29392.1 - 0.82 8.4 8.9 0.053 12.3 0.3 2.5 3 0 0 3 3 3 0 PalH/RIM21 ABC_tran PF00005.22 CAR29393.1 - 7.9e-59 197.8 0.1 1.4e-34 119.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CAR29393.1 - 2.5e-48 164.8 43.4 5.8e-34 117.7 8.1 4.4 4 1 0 4 4 4 3 ABC transporter transmembrane region AAA_21 PF13304.1 CAR29393.1 - 1.3e-10 41.7 7.8 3.2e-06 27.3 0.1 4.6 4 1 0 4 4 3 2 AAA domain SMC_N PF02463.14 CAR29393.1 - 8e-10 38.3 5.0 1.3e-05 24.5 0.5 3.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CAR29393.1 - 1.3e-08 35.4 8.5 1.1e-05 25.9 0.1 3.1 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 CAR29393.1 - 2.1e-07 30.3 1.1 0.004 16.6 0.0 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CAR29393.1 - 2.7e-06 28.2 0.0 0.061 14.1 0.0 3.1 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 CAR29393.1 - 9.3e-06 24.9 0.1 0.14 11.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 T2SE PF00437.15 CAR29393.1 - 1.5e-05 24.0 0.0 0.0085 15.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein Miro PF08477.8 CAR29393.1 - 3e-05 24.5 0.0 0.3 11.6 0.0 3.0 2 0 0 2 2 2 2 Miro-like protein ATP_bind_1 PF03029.12 CAR29393.1 - 4.2e-05 23.2 0.0 1.5 8.3 0.0 3.4 3 0 0 3 3 3 2 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 CAR29393.1 - 6.4e-05 23.0 0.3 0.1 12.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 CAR29393.1 - 7.9e-05 22.5 0.3 0.029 14.3 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CAR29393.1 - 8.4e-05 22.7 0.0 1.1 9.4 0.0 3.3 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 CAR29393.1 - 0.00013 21.1 0.0 0.22 10.5 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin DUF87 PF01935.12 CAR29393.1 - 0.00071 19.4 0.8 0.7 9.6 0.0 2.9 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA PF00004.24 CAR29393.1 - 0.001 19.2 0.2 1.8 8.7 0.0 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 CAR29393.1 - 0.0011 18.5 0.2 0.93 8.9 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_25 PF13481.1 CAR29393.1 - 0.0013 18.1 0.0 0.72 9.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 CAR29393.1 - 0.0046 16.4 1.0 0.4 10.0 0.1 3.2 3 0 0 3 3 3 1 AAA-like domain MobB PF03205.9 CAR29393.1 - 0.0061 16.2 1.1 1.9 8.1 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 CAR29393.1 - 0.0065 16.7 0.0 5.4 7.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 CAR29393.1 - 0.0083 15.9 4.4 0.87 9.3 0.2 3.0 3 0 0 3 3 3 2 Dynamin family AAA_24 PF13479.1 CAR29393.1 - 0.015 14.8 0.5 0.97 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 CAR29393.1 - 0.021 13.8 9.4 0.15 11.1 0.1 3.2 3 0 0 3 3 3 0 AAA ATPase domain AAA_33 PF13671.1 CAR29393.1 - 0.042 13.7 0.0 10 5.9 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.1 CAR29393.1 - 0.047 13.2 0.2 11 5.5 0.0 2.7 3 0 0 3 3 3 0 AAA domain Guanylate_kin PF00625.16 CAR29393.1 - 0.05 13.0 0.1 2.2 7.6 0.0 2.8 2 0 0 2 2 2 0 Guanylate kinase ResIII PF04851.10 CAR29393.1 - 0.058 13.2 0.1 3.8 7.2 0.0 3.1 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit cobW PF02492.14 CAR29393.1 - 0.16 11.3 1.7 7.2 6.0 0.3 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 CAR29393.1 - 0.21 10.3 0.1 0.46 9.2 0.0 1.4 1 0 0 1 1 1 0 ArgK protein AAA_19 PF13245.1 CAR29393.1 - 0.37 10.5 0.7 4.7 7.0 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain RRM_1 PF00076.17 CAR29394.1 - 1.5e-21 75.7 3.3 4.3e-12 45.4 0.2 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR29394.1 - 8.2e-15 54.5 0.5 2.8e-06 27.2 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR29394.1 - 0.002 17.9 0.4 1.3 8.9 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L7Ae PF01248.21 CAR29395.1 - 3.9e-23 80.7 0.5 6.3e-23 80.1 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CAR29395.1 - 0.00068 19.4 0.1 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 FGGY_C PF02782.11 CAR29396.1 - 1.4e-71 240.1 0.3 2.4e-71 239.4 0.2 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 CAR29396.1 - 4.1e-46 157.2 0.0 5.1e-38 130.7 0.0 2.9 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain MIP PF00230.15 CAR29397.1 - 7.1e-69 231.7 5.4 9.3e-69 231.3 3.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein V-SNARE_C PF12352.3 CAR29398.1 - 4.1e-14 52.4 0.6 4.1e-14 52.4 0.4 2.9 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec34 PF04136.10 CAR29398.1 - 0.0015 18.2 2.8 0.0015 18.2 1.9 2.2 1 1 1 2 2 2 1 Sec34-like family TBPIP PF07106.8 CAR29398.1 - 0.032 13.7 5.2 0.053 13.0 3.3 1.6 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Baculo_11_kDa PF06143.6 CAR29398.1 - 0.083 12.2 0.4 0.083 12.2 0.3 2.2 2 0 0 2 2 2 0 Baculovirus 11 kDa family FlgN PF05130.7 CAR29398.1 - 0.26 11.5 10.4 0.056 13.6 4.4 1.9 2 0 0 2 2 2 0 FlgN protein DUF342 PF03961.8 CAR29398.1 - 0.49 8.7 2.8 0.61 8.4 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Not3 PF04065.10 CAR29398.1 - 0.64 9.2 7.5 1.5 8.0 4.6 1.8 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component DUF972 PF06156.8 CAR29398.1 - 7 7.0 7.4 18 5.7 3.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Autophagy_act_C PF03987.10 CAR29399.1 - 5.4e-06 26.4 1.1 6.2e-05 23.0 0.7 2.3 1 1 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Fer2_3 PF13085.1 CAR29400.1 - 2.8e-31 107.6 0.1 5e-31 106.7 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 CAR29400.1 - 9.3e-10 38.7 7.5 9.3e-10 38.7 5.2 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 CAR29400.1 - 6.8e-09 35.6 5.8 6.8e-09 35.6 4.0 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 CAR29400.1 - 1.9e-05 24.9 2.7 1.9e-05 24.9 1.8 2.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 CAR29400.1 - 0.00086 19.5 8.1 0.03 14.5 0.3 3.0 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.22 CAR29400.1 - 0.0013 18.4 5.9 0.0073 16.0 1.3 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_10 PF13237.1 CAR29400.1 - 0.0014 18.3 7.0 0.0014 18.3 4.8 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 CAR29400.1 - 0.0027 18.0 5.9 0.0027 18.0 4.1 2.4 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4_15 PF13459.1 CAR29400.1 - 4.7 7.8 8.0 1.4 9.5 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S single cluster domain DUF1162 PF06650.7 CAR29401.1 - 1.7e-83 280.0 4.4 8.6e-82 274.4 0.4 3.6 3 1 1 4 4 4 3 Protein of unknown function (DUF1162) Chorein_N PF12624.2 CAR29401.1 - 4.1e-39 132.7 0.0 1.7e-38 130.7 0.0 2.2 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Ecm29 PF13001.2 CAR29402.1 - 1.2e-129 433.0 8.9 3.2e-128 428.3 1.5 2.6 3 0 0 3 3 3 2 Proteasome stabiliser HEAT PF02985.17 CAR29402.1 - 2.4e-16 58.2 5.3 0.015 15.3 0.0 8.4 7 0 0 7 7 7 4 HEAT repeat Vac14_Fab1_bd PF12755.2 CAR29402.1 - 6.1e-06 26.5 0.2 0.052 13.9 0.0 4.8 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CAR29402.1 - 7e-05 23.1 1.6 45 4.7 0.0 7.2 7 0 0 7 7 7 0 HEAT-like repeat DUF1546 PF07571.8 CAR29402.1 - 0.0059 16.6 0.2 20 5.3 0.0 4.8 5 0 0 5 5 5 1 Protein of unknown function (DUF1546) ubiquitin PF00240.18 CAR29403.1 - 2.5e-202 654.6 39.2 2.1e-33 113.5 0.6 6.0 6 0 0 6 6 6 6 Ubiquitin family Rad60-SLD PF11976.3 CAR29403.1 - 7.5e-116 377.9 35.7 8.3e-19 67.0 0.5 6.0 6 0 0 6 6 6 6 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CAR29403.1 - 1.3e-34 118.2 20.4 0.00028 21.0 0.1 8.0 6 6 0 6 6 6 6 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CAR29403.1 - 1.9e-31 108.9 4.9 0.0019 17.9 0.0 6.0 6 0 0 6 6 6 6 Telomere stability and silencing DUF2407 PF10302.4 CAR29403.1 - 2.7e-19 69.1 7.4 0.23 11.6 0.0 6.2 1 1 3 6 6 6 6 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 CAR29403.1 - 2.7e-19 69.0 8.4 0.23 11.3 0.0 6.9 6 0 0 6 6 6 6 Ubiquitin-2 like Rad60 SUMO-like DUF2870 PF11069.3 CAR29403.1 - 6.9e-16 58.0 0.0 2.6 8.1 0.0 6.9 6 0 0 6 6 6 6 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 CAR29403.1 - 3.1e-08 33.4 12.7 8.3 6.4 0.0 6.2 6 0 0 6 6 6 6 GLUT4 regulating protein TUG FlgD_ig PF13860.1 CAR29403.1 - 5e-06 26.1 11.7 24 4.7 0.0 6.2 6 0 0 6 6 6 0 FlgD Ig-like domain Big_3_3 PF13750.1 CAR29403.1 - 2.1e-05 24.0 0.1 83 2.5 0.0 5.7 6 0 0 6 6 6 0 Bacterial Ig-like domain (group 3) ACT_4 PF13291.1 CAR29403.1 - 0.00013 22.1 2.8 1.7e+02 2.6 0.0 6.0 6 0 0 6 6 6 0 ACT domain Plexin_cytopl PF08337.7 CAR29403.1 - 0.00017 20.0 23.6 4 5.6 0.2 7.8 7 5 0 7 7 7 5 Plexin cytoplasmic RasGAP domain Tash_PEST PF07708.6 CAR29403.1 - 0.031 14.1 47.6 5.5 7.0 1.2 6.4 6 0 0 6 6 6 0 Tash protein PEST motif GABP-alpha PF11620.3 CAR29403.1 - 0.042 13.8 14.4 84 3.2 0.1 5.9 6 0 0 6 6 6 0 GA-binding protein alpha chain FERM_N PF09379.5 CAR29403.1 - 0.66 10.0 22.7 75 3.4 0.1 8.1 6 6 0 6 6 6 0 FERM N-terminal domain DUF3781 PF12636.2 CAR29403.1 - 1.9 8.5 15.0 1.7e+02 2.2 0.1 5.9 6 0 0 6 6 6 0 Protein of unknown function (DUF3781) ENTH PF01417.15 CAR29404.1 - 4.2e-32 110.6 0.3 6e-32 110.1 0.2 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 CAR29404.1 - 0.0015 17.3 0.1 0.0022 16.7 0.0 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.14 CAR29404.1 - 0.062 12.9 0.3 0.15 11.7 0.2 1.7 1 1 0 1 1 1 0 VHS domain Prp19 PF08606.6 CAR29405.1 - 4.3e-28 96.8 2.3 8.2e-28 95.9 1.6 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like zf-Nse PF11789.3 CAR29405.1 - 0.014 14.8 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 CAR29405.1 - 0.12 12.3 0.1 0.47 10.4 0.0 2.0 2 0 0 2 2 2 0 U-box domain RabGAP-TBC PF00566.13 CAR29406.1 - 5.6e-10 39.0 0.1 0.00084 18.8 0.0 2.7 2 0 0 2 2 2 2 Rab-GTPase-TBC domain zf-C2H2 PF00096.21 CAR29408.1 - 3.9e-07 30.0 19.3 0.00013 22.1 1.4 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CAR29408.1 - 0.00095 19.3 17.9 0.0014 18.8 0.3 3.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CAR29408.1 - 0.0088 16.2 3.1 0.0088 16.2 2.2 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CAR29408.1 - 0.18 11.9 2.9 0.44 10.7 0.1 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CAR29408.1 - 0.49 10.6 4.6 0.6 10.3 0.0 3.2 3 1 1 4 4 4 0 Zinc-finger of C2H2 type HNH PF01844.18 CAR29408.1 - 5.1 7.0 7.8 3.8 7.4 2.1 2.5 2 0 0 2 2 2 0 HNH endonuclease Clp1 PF06807.9 CAR29409.1 - 2.1e-11 43.9 0.0 5.2e-11 42.6 0.0 1.7 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 AAA_14 PF13173.1 CAR29409.1 - 8.6e-05 22.4 0.8 0.0002 21.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 CAR29409.1 - 0.0018 18.0 0.0 0.0032 17.1 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 CAR29409.1 - 0.045 13.7 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 CAR29409.1 - 0.08 12.4 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family DAP3 PF10236.4 CAR29409.1 - 0.094 11.6 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 MMR_HSR1 PF01926.18 CAR29409.1 - 0.1 12.5 0.3 0.26 11.2 0.2 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_17 PF13207.1 CAR29409.1 - 0.12 13.2 0.0 0.85 10.4 0.0 2.5 3 0 0 3 3 3 0 AAA domain Arf PF00025.16 CAR29409.1 - 0.13 11.5 0.1 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family Miro PF08477.8 CAR29409.1 - 0.15 12.5 0.0 0.4 11.2 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AAA PF00004.24 CAR29410.1 - 7.3e-93 307.7 0.0 6.7e-47 158.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CAR29410.1 - 3.6e-15 55.6 0.0 4.2e-08 32.5 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CAR29410.1 - 7.1e-12 45.6 1.3 0.00024 21.1 0.0 3.8 3 2 0 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 CAR29410.1 - 1.3e-11 45.3 0.0 1.9e-06 28.7 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CAR29410.1 - 1.3e-10 41.4 0.1 0.0056 16.8 0.0 5.0 2 2 2 4 4 4 2 AAA domain Zeta_toxin PF06414.7 CAR29410.1 - 2.9e-10 39.5 0.0 0.0007 18.7 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_5 PF07728.9 CAR29410.1 - 5.9e-10 39.0 0.1 0.00084 19.0 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CAR29410.1 - 1.2e-09 38.1 0.0 0.00052 19.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 CAR29410.1 - 2.1e-09 37.5 0.0 0.00036 20.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 CAR29410.1 - 4.1e-09 36.4 0.0 0.0029 17.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 CAR29410.1 - 1.2e-08 34.1 0.0 0.00035 19.3 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus RNA_helicase PF00910.17 CAR29410.1 - 5.1e-08 33.0 0.0 0.0057 16.8 0.0 3.2 2 0 0 2 2 2 2 RNA helicase Vps4_C PF09336.5 CAR29410.1 - 6.2e-08 32.4 1.0 4.6e-05 23.2 0.0 3.5 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain ABC_tran PF00005.22 CAR29410.1 - 2.5e-07 31.0 0.0 0.013 15.8 0.0 3.0 2 0 0 2 2 2 2 ABC transporter AAA_19 PF13245.1 CAR29410.1 - 5.5e-07 29.2 0.3 0.05 13.3 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain IstB_IS21 PF01695.12 CAR29410.1 - 7.5e-07 28.7 0.3 0.021 14.2 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.1 CAR29410.1 - 2e-06 27.8 0.0 0.043 13.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 CAR29410.1 - 2.9e-06 27.6 8.8 0.00023 21.4 0.0 3.7 5 0 0 5 5 2 2 AAA domain Mg_chelatase PF01078.16 CAR29410.1 - 3e-06 26.5 0.2 0.042 13.0 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 CAR29410.1 - 9.6e-06 25.1 3.1 0.37 10.1 0.0 4.2 2 2 2 4 4 4 2 AAA domain AAA_3 PF07726.6 CAR29410.1 - 1.3e-05 24.8 0.0 0.13 11.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CAR29410.1 - 1.9e-05 24.3 0.0 0.46 10.1 0.0 3.4 3 0 0 3 3 3 2 NACHT domain SKI PF01202.17 CAR29410.1 - 3.4e-05 23.7 0.0 0.23 11.3 0.0 3.2 2 0 0 2 2 2 2 Shikimate kinase Cytidylate_kin2 PF13189.1 CAR29410.1 - 5.9e-05 23.0 0.0 0.0048 16.8 0.0 2.7 2 0 0 2 2 2 1 Cytidylate kinase-like family SRPRB PF09439.5 CAR29410.1 - 6.6e-05 22.2 0.0 1.8 7.7 0.0 3.7 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit NB-ARC PF00931.17 CAR29410.1 - 7.4e-05 21.7 0.1 0.31 9.8 0.0 3.7 4 0 0 4 4 4 1 NB-ARC domain DUF815 PF05673.8 CAR29410.1 - 0.00019 20.4 0.0 0.13 11.1 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.1 CAR29410.1 - 0.00021 21.3 0.0 0.66 10.0 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activat PF00158.21 CAR29410.1 - 0.00026 20.5 0.0 0.23 10.9 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain Viral_helicase1 PF01443.13 CAR29410.1 - 0.00027 20.5 0.0 0.88 9.0 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Rad17 PF03215.10 CAR29410.1 - 0.00043 19.0 0.0 0.22 10.1 0.0 2.8 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein CPT PF07931.7 CAR29410.1 - 0.00055 19.6 0.0 0.013 15.0 0.0 2.4 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein Arch_ATPase PF01637.13 CAR29410.1 - 0.00079 19.1 0.0 2.6 7.6 0.0 3.3 2 1 1 3 3 3 1 Archaeal ATPase AAA_11 PF13086.1 CAR29410.1 - 0.00081 19.0 0.9 0.5 9.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain KaiC PF06745.8 CAR29410.1 - 0.0018 17.4 0.1 1.4 8.0 0.0 3.2 3 0 0 3 3 3 1 KaiC Parvo_NS1 PF01057.12 CAR29410.1 - 0.0021 16.9 0.0 1.6 7.5 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_24 PF13479.1 CAR29410.1 - 0.0026 17.3 0.0 2.3 7.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 CAR29410.1 - 0.0053 16.0 0.1 1.6 7.9 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein ATP-synt_ab PF00006.20 CAR29410.1 - 0.0054 16.2 0.0 1.8 8.0 0.0 2.6 3 0 0 3 3 2 1 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.10 CAR29410.1 - 0.012 15.3 0.1 4.1 7.0 0.0 3.0 3 0 0 3 3 2 0 NTPase UPF0079 PF02367.12 CAR29410.1 - 0.015 14.9 0.0 6.2 6.4 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 CAR29410.1 - 0.019 14.4 0.0 6.7 6.1 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AFG1_ATPase PF03969.11 CAR29410.1 - 0.041 12.6 0.2 7.6 5.2 0.0 3.0 3 1 0 3 3 2 0 AFG1-like ATPase ResIII PF04851.10 CAR29410.1 - 0.052 13.3 0.2 5.4 6.8 0.0 3.0 3 1 0 3 3 2 0 Type III restriction enzyme, res subunit IPT PF01745.11 CAR29410.1 - 0.053 12.6 0.5 29 3.7 0.0 3.1 3 0 0 3 3 3 0 Isopentenyl transferase DUF258 PF03193.11 CAR29410.1 - 0.057 12.5 0.1 0.88 8.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 FeoB_N PF02421.13 CAR29410.1 - 0.059 12.6 0.1 2.2 7.5 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B MMR_HSR1 PF01926.18 CAR29410.1 - 0.062 13.2 0.0 3.5 7.6 0.0 2.9 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.1 CAR29410.1 - 0.12 11.9 0.0 6.1 6.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.1 CAR29410.1 - 2.2 8.5 0.0 2.2 8.5 0.0 4.2 5 0 0 5 5 3 0 AAA domain DUF2456 PF10445.4 CAR29411.1 - 6.3e-26 90.1 2.0 1.1e-25 89.3 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2456) MatE PF01554.13 CAR29411.1 - 0.01 15.4 0.3 0.027 14.0 0.2 1.7 1 1 0 1 1 1 0 MatE Spc7 PF08317.6 CAR29412.1 - 6.1e-66 222.3 15.3 6.1e-66 222.3 10.6 1.9 2 0 0 2 2 2 1 Spc7 kinetochore protein Fimbrial_CS1 PF04449.7 CAR29412.1 - 0.022 14.7 2.0 5.3 7.0 0.0 3.5 2 1 1 3 3 3 0 CS1 type fimbrial major subunit DUF2564 PF10819.3 CAR29412.1 - 0.17 12.0 7.6 4.2 7.5 2.6 3.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2564) Nup96 PF12110.3 CAR29413.1 - 7.9e-49 166.3 3.2 1.5e-48 165.4 2.2 1.5 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 CAR29413.1 - 8.5e-49 164.9 0.0 1.6e-48 164.1 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 CAR29413.1 - 6.7e-11 42.4 102.4 5.3e-07 29.8 31.8 4.3 2 1 1 3 3 3 2 Nucleoporin FG repeat region MTS_N PF08468.6 CAR29413.1 - 0.024 14.4 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain N-terminal Shugoshin_N PF07558.6 CAR29413.1 - 0.53 10.0 7.4 0.022 14.4 0.7 2.0 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region ParA PF10609.4 CAR29414.1 - 4e-36 122.7 0.0 1.8e-35 120.6 0.0 2.0 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 CAR29414.1 - 4.4e-16 58.8 0.0 6.6e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 CAR29414.1 - 5.7e-06 25.6 0.0 9e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.1 CAR29414.1 - 1.2e-05 25.3 0.0 6.4e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 CAR29414.1 - 0.00037 19.6 0.6 0.0082 15.2 0.0 2.4 2 1 1 3 3 3 1 Anion-transporting ATPase DUF258 PF03193.11 CAR29414.1 - 0.003 16.7 0.0 0.0056 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 CAR29414.1 - 0.0073 15.7 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.1 CAR29414.1 - 0.012 15.2 0.0 0.16 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.13 CAR29414.1 - 0.048 12.8 0.0 1.7 7.7 0.0 2.6 2 1 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NB-ARC PF00931.17 CAR29414.1 - 0.15 10.9 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Rad17 PF03215.10 CAR29414.1 - 0.19 10.3 0.0 0.27 9.8 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein TF_Zn_Ribbon PF08271.7 CAR29414.1 - 8.3 5.8 7.0 0.3 10.4 0.3 2.0 2 0 0 2 2 2 0 TFIIB zinc-binding XLF PF09302.6 CAR29415.1 - 1.4e-12 47.7 0.6 2e-12 47.2 0.4 1.3 1 0 0 1 1 1 1 XLF (XRCC4-like factor) ORF6C PF10552.4 CAR29415.1 - 0.067 12.9 2.1 0.15 11.8 1.4 1.6 1 0 0 1 1 1 0 ORF6C domain IncA PF04156.9 CAR29415.1 - 0.16 11.5 3.0 0.38 10.3 2.1 1.6 1 0 0 1 1 1 0 IncA protein Pox_A_type_inc PF04508.7 CAR29415.1 - 0.99 9.3 5.9 0.16 11.8 0.5 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat RRM_1 PF00076.17 CAR29416.1 - 3.6e-26 90.5 0.2 2.5e-07 30.2 0.0 4.9 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR29416.1 - 8.7e-26 89.7 0.6 1.7e-07 31.0 0.0 5.0 5 1 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR29416.1 - 1.7e-22 78.9 1.4 8.7e-07 28.7 0.2 4.7 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CAR29416.1 - 0.0046 16.6 0.0 3.1 7.6 0.0 2.9 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif CdhC PF03598.10 CAR29417.1 - 0.038 12.4 0.0 0.056 11.9 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit MF_alpha PF04648.7 CAR29418.1 - 2.1e-17 62.1 15.1 2.7 8.3 0.0 8.2 8 0 0 8 8 8 8 Yeast mating factor alpha hormone DUF4601 PF15373.1 CAR29418.1 - 3.4e-06 26.2 0.4 0.37 9.5 0.0 2.8 1 1 3 4 4 4 3 Domain of unknown function (DUF4601) Amelogenin PF02948.10 CAR29418.1 - 0.0016 19.1 1.1 1.3 9.5 0.1 2.0 1 1 1 2 2 2 2 Amelogenin DUF3473 PF11959.3 CAR29418.1 - 0.0021 17.4 7.5 13 5.2 0.1 5.2 1 1 6 7 7 7 3 Domain of unknown function (DUF3473) zf-C2H2_jaz PF12171.3 CAR29418.1 - 0.14 12.3 6.1 2.2e+02 2.1 0.0 5.1 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding Spore_YhaL PF14147.1 CAR29418.1 - 1.4 8.4 10.8 86 2.6 0.0 5.8 5 3 2 7 7 7 0 Sporulation protein YhaL NAD_kinase PF01513.16 CAR29419.1 - 1.6e-52 178.0 0.0 2.3e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 CAR29419.1 - 0.03 13.7 0.0 0.059 12.8 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain UQ_con PF00179.21 CAR29420.1 - 4.4e-20 71.5 0.0 4.7e-20 71.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CAR29420.1 - 0.00092 19.0 0.0 0.00096 19.0 0.0 1.2 1 0 0 1 1 1 1 RWD domain MAD PF05557.8 CAR29421.1 - 4.2e-25 87.9 85.0 4.3e-24 84.6 58.9 1.9 1 1 0 1 1 1 1 Mitotic checkpoint protein SNase PF00565.12 CAR29422.1 - 1.5e-26 92.7 0.0 2.1e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue DUF1049 PF06305.6 CAR29422.1 - 0.14 11.6 0.0 0.34 10.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) MBOAT PF03062.14 CAR29423.1 - 8.4e-54 182.8 21.2 1.5e-53 182.0 14.7 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family ESSS PF10183.4 CAR29423.1 - 0.24 11.8 0.8 1.3 9.4 0.0 2.6 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Pkinase PF00069.20 CAR29424.1 - 4.1e-21 75.2 0.2 8.1e-21 74.3 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR29424.1 - 5.9e-14 51.7 0.0 1e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ParcG PF10274.4 CAR29424.1 - 0.029 14.2 0.4 0.088 12.6 0.3 1.9 1 0 0 1 1 1 0 Parkin co-regulated protein RRM_1 PF00076.17 CAR29426.1 - 2.6e-10 39.7 0.1 7.5e-10 38.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR29426.1 - 4e-08 33.1 0.0 1e-07 31.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR29426.1 - 0.00021 21.0 0.0 0.00039 20.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIF_alpha PF05793.7 CAR29426.1 - 5.7 5.1 49.0 10 4.3 34.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF544 PF04424.8 CAR29427.1 - 1.3e-29 102.4 0.0 2.2e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF544) CCDC50_N PF15295.1 CAR29427.1 - 0.047 13.6 1.9 0.086 12.7 1.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus FHA PF00498.21 CAR29428.1 - 4.9e-06 26.5 0.1 3.8e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 FHA domain NUFIP1 PF10453.4 CAR29430.1 - 7.5e-18 63.7 4.0 2.1e-17 62.3 2.8 1.8 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) APC_CDC26 PF10471.4 CAR29430.1 - 0.032 14.9 2.8 0.032 14.9 2.0 2.6 2 1 1 3 3 3 0 Anaphase-promoting complex APC subunit 1 DUF413 PF04219.7 CAR29430.1 - 0.12 12.0 0.9 0.22 11.2 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF DUF1828 PF08861.5 CAR29430.1 - 0.21 11.2 1.7 0.43 10.2 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF1828 RabGAP-TBC PF00566.13 CAR29430.1 - 0.52 9.7 4.3 0.78 9.1 3.0 1.3 1 0 0 1 1 1 0 Rab-GTPase-TBC domain MPC PF03650.8 CAR29431.1 - 1.1e-40 138.3 0.4 1.3e-40 138.0 0.3 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Rad9 PF04139.8 CAR29432.1 - 2.2e-08 33.5 0.7 8.1e-07 28.4 0.5 2.3 1 1 0 1 1 1 1 Rad9 Adaptin_N PF01602.15 CAR29433.1 - 2.7e-115 385.7 8.8 3.7e-115 385.2 6.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CAR29433.1 - 9e-11 41.9 5.6 8.8e-10 38.7 0.2 3.5 2 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CAR29433.1 - 7.8e-07 29.3 0.1 0.15 12.3 0.0 4.5 2 1 3 5 5 5 3 HEAT repeats HEAT PF02985.17 CAR29433.1 - 1.2e-06 28.0 1.7 6.1 7.2 0.0 6.4 6 0 0 6 6 6 2 HEAT repeat Vac14_Fab1_bd PF12755.2 CAR29433.1 - 0.015 15.6 2.7 0.092 13.1 0.2 3.5 3 1 1 4 4 4 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CAR29433.1 - 0.27 11.7 0.5 5.4 7.6 0.0 3.5 3 1 1 4 4 4 0 HEAT-like repeat KxDL PF10241.4 CAR29434.1 - 1.2e-08 34.7 0.4 1.9e-08 34.0 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein TLD PF07534.11 CAR29435.1 - 1.1e-30 106.4 0.3 4.9e-30 104.3 0.2 1.9 1 1 0 1 1 1 1 TLD DEAD PF00270.24 CAR29436.1 - 2.5e-50 170.2 2.6 5.5e-49 165.9 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR29436.1 - 2.8e-30 103.9 0.0 2.1e-28 98.0 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAR29436.1 - 1.1e-08 35.0 0.0 1.1e-08 35.0 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 CAR29436.1 - 0.0062 15.6 0.0 0.0062 15.6 0.0 3.3 2 1 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.1 CAR29436.1 - 0.13 12.3 3.5 0.3 11.2 1.0 2.6 3 1 0 3 3 3 0 AAA domain LytR_C PF13399.1 CAR29436.1 - 0.18 12.1 2.7 31 5.0 0.0 3.7 5 0 0 5 5 5 0 LytR cell envelope-related transcriptional attenuator Mem_trans PF03547.13 CAR29436.1 - 0.4 8.9 1.8 0.42 8.8 1.2 1.2 1 0 0 1 1 1 0 Membrane transport protein SR-25 PF10500.4 CAR29436.1 - 1.9 7.9 33.2 4.8 6.5 23.0 1.8 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AA_permease_2 PF13520.1 CAR29437.1 - 1.8e-48 165.1 51.7 2.2e-48 164.8 35.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CAR29437.1 - 1.3e-25 89.7 38.7 1.7e-25 89.3 26.9 1.0 1 0 0 1 1 1 1 Amino acid permease Ribosomal_L30_N PF08079.7 CAR29438.1 - 3.3e-20 71.8 12.1 6.5e-20 70.9 8.4 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 CAR29438.1 - 1.2e-18 66.3 1.7 2.4e-18 65.4 1.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ig_Tie2_1 PF10430.4 CAR29438.1 - 0.13 12.6 0.1 0.24 11.7 0.1 1.4 1 0 0 1 1 1 0 Tie-2 Ig-like domain 1 DUF1771 PF08590.5 CAR29439.1 - 7e-18 64.4 13.0 1.2e-17 63.7 9.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 CAR29439.1 - 2.3e-17 62.9 0.1 7.7e-16 58.0 0.0 2.6 3 0 0 3 3 3 1 Smr domain MRP-L46 PF11788.3 CAR29439.1 - 0.016 15.8 0.9 0.028 15.0 0.6 1.5 1 0 0 1 1 1 0 39S mitochondrial ribosomal protein L46 Reo_sigmaC PF04582.7 CAR29440.1 - 0.0071 15.5 0.0 0.0095 15.1 0.0 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Spatacsin_C PF14649.1 CAR29440.1 - 0.027 13.3 0.4 0.04 12.7 0.3 1.2 1 0 0 1 1 1 0 Spatacsin C-terminus SlyX PF04102.7 CAR29440.1 - 0.065 13.6 4.8 1.4 9.3 0.1 2.4 2 0 0 2 2 2 0 SlyX SAB PF04382.8 CAR29440.1 - 0.082 12.6 1.6 0.18 11.5 1.1 1.6 1 0 0 1 1 1 0 SAB domain Tropomyosin_1 PF12718.2 CAR29440.1 - 0.13 12.1 7.8 0.66 9.8 5.4 1.9 1 1 0 1 1 1 0 Tropomyosin like DUF3810 PF12725.2 CAR29440.1 - 0.19 10.6 2.4 0.28 10.0 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3810) DUF641 PF04859.7 CAR29440.1 - 2.3 8.0 8.0 2.9 7.6 2.5 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) HSF_DNA-bind PF00447.12 CAR29441.1 - 2.5e-35 120.7 2.4 5.8e-35 119.5 1.7 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding AFT PF08731.6 CAR29443.1 - 4.2e-45 152.4 1.7 4.2e-45 152.4 1.2 2.6 2 1 0 2 2 2 1 Transcription factor AFT DBD_Tnp_Mut PF03108.10 CAR29443.1 - 0.0028 17.1 0.6 0.43 10.1 0.0 2.4 2 0 0 2 2 2 2 MuDR family transposase FAR1 PF03101.10 CAR29443.1 - 0.029 14.8 0.7 0.029 14.8 0.5 2.4 2 0 0 2 2 2 0 FAR1 DNA-binding domain RNA_POL_M_15KD PF02150.11 CAR29444.1 - 2.3e-15 55.9 4.9 2.3e-15 55.9 3.4 2.6 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.13 CAR29444.1 - 8.6e-15 54.0 15.7 2.1e-14 52.8 1.6 3.1 2 1 1 3 3 3 1 Transcription factor S-II (TFIIS) Lar_restr_allev PF14354.1 CAR29444.1 - 0.0019 18.4 2.4 0.028 14.7 0.2 2.2 2 0 0 2 2 2 1 Restriction alleviation protein Lar Rubredoxin PF00301.15 CAR29444.1 - 0.0025 17.6 3.6 13 5.7 0.0 4.0 4 0 0 4 4 4 0 Rubredoxin zf-UBP PF02148.14 CAR29444.1 - 0.037 14.1 3.8 0.74 9.9 0.3 2.3 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein DZR PF12773.2 CAR29444.1 - 0.044 13.5 8.2 0.2 11.4 0.4 2.4 2 1 0 2 2 2 0 Double zinc ribbon zf-CHY PF05495.7 CAR29444.1 - 0.064 13.4 6.6 0.29 11.3 0.8 2.3 2 0 0 2 2 2 0 CHY zinc finger Zn_Tnp_IS1595 PF12760.2 CAR29444.1 - 0.081 12.7 11.9 0.13 12.0 0.5 3.0 2 1 1 3 3 3 0 Transposase zinc-ribbon domain Cytochrom_NNT PF03264.9 CAR29444.1 - 0.086 12.2 0.5 0.086 12.2 0.3 2.0 2 1 0 2 2 2 0 NapC/NirT cytochrome c family, N-terminal region Cytochrome_C7 PF14522.1 CAR29444.1 - 0.097 12.3 2.8 0.39 10.3 0.1 2.3 2 0 0 2 2 2 0 Cytochrome c7 C1_4 PF07975.7 CAR29444.1 - 0.11 12.5 10.9 0.36 10.8 0.7 3.0 2 1 1 3 3 3 0 TFIIH C1-like domain DUF2387 PF09526.5 CAR29444.1 - 0.15 12.0 4.0 4.2 7.3 0.4 2.4 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) Cytochrom_c3_2 PF14537.1 CAR29444.1 - 0.2 12.0 2.1 0.57 10.5 0.2 2.1 2 0 0 2 2 2 0 Cytochrome c3 GFA PF04828.9 CAR29444.1 - 0.27 11.1 4.1 5.3 7.0 0.7 2.4 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme IBR PF01485.16 CAR29444.1 - 0.32 10.8 6.7 1.3 8.9 0.3 2.5 2 1 0 2 2 2 0 IBR domain DUF2296 PF10058.4 CAR29444.1 - 3.2 7.5 7.1 2.9 7.6 0.3 2.5 2 1 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Zn-ribbon_8 PF09723.5 CAR29444.1 - 3.2 7.7 12.8 4.4 7.3 0.0 3.9 3 1 1 4 4 4 0 Zinc ribbon domain HypA PF01155.14 CAR29444.1 - 3.6 7.2 7.8 17 5.1 3.1 2.8 1 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family RPA_interact_C PF14768.1 CAR29444.1 - 8.6 6.8 10.3 2.6 8.5 0.8 2.6 2 2 0 2 2 2 0 Replication protein A interacting C-terminal zf-H2C2_2 PF13465.1 CAR29444.1 - 9.2 6.7 7.5 39 4.7 0.0 3.4 4 0 0 4 4 3 0 Zinc-finger double domain Ribosomal_L12 PF00542.14 CAR29445.1 - 1.9e-18 66.1 6.7 1.9e-18 66.1 4.7 1.9 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_60s PF00428.14 CAR29445.1 - 0.0062 16.9 8.7 0.0062 16.9 6.0 2.5 1 1 2 3 3 3 1 60s Acidic ribosomal protein BID PF06393.6 CAR29445.1 - 0.05 12.9 0.2 0.077 12.3 0.1 1.3 1 0 0 1 1 1 0 BH3 interacting domain (BID) Pkinase PF00069.20 CAR29446.1 - 4.6e-69 232.4 0.0 5.5e-69 232.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR29446.1 - 1.2e-38 132.6 0.0 1.6e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR29446.1 - 0.00017 20.6 0.0 0.00032 19.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like WaaY PF06176.6 CAR29446.1 - 0.0038 16.4 0.4 0.006 15.8 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.18 CAR29446.1 - 0.054 13.2 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CAR29446.1 - 0.11 11.2 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.20 CAR29447.1 - 3.5e-41 141.0 0.0 6.3e-41 140.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR29447.1 - 2.1e-16 59.7 0.0 3.2e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CAR29447.1 - 0.0047 16.6 1.0 0.086 12.5 0.0 2.7 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CAR29447.1 - 0.089 11.7 0.0 0.19 10.6 0.0 1.6 2 0 0 2 2 2 0 Kinase-like CBFD_NFYB_HMF PF00808.18 CAR29448.1 - 4.7e-25 87.4 0.0 6.9e-25 86.8 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CAR29448.1 - 2.3e-05 24.4 0.0 3.8e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.8 CAR29448.1 - 0.07 13.4 0.1 0.35 11.2 0.0 2.0 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Bromo_TP PF07524.8 CAR29448.1 - 0.072 12.8 0.0 0.31 10.8 0.0 1.9 2 0 0 2 2 2 0 Bromodomain associated Lon_C PF05362.8 CAR29449.1 - 4.1e-66 222.1 0.0 7.8e-66 221.2 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 CAR29449.1 - 5.5e-40 137.2 0.6 1.7e-39 135.6 0.4 1.9 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 CAR29449.1 - 2.1e-23 82.9 0.0 5.8e-23 81.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 CAR29449.1 - 1.1e-06 28.2 0.0 2.8e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 CAR29449.1 - 3e-06 27.0 0.0 8.9e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.6 CAR29449.1 - 2.4e-05 23.1 0.0 0.0003 19.5 0.0 2.2 2 0 0 2 2 2 1 PrkA AAA domain AAA_22 PF13401.1 CAR29449.1 - 3.2e-05 24.0 0.3 0.00045 20.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CAR29449.1 - 0.00016 22.5 0.2 0.0014 19.3 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 CAR29449.1 - 0.00026 21.0 2.5 0.0027 17.7 0.0 3.3 4 0 0 4 4 3 1 AAA ATPase domain RuvB_N PF05496.7 CAR29449.1 - 0.0012 17.9 0.0 0.0094 15.0 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CAR29449.1 - 0.0024 17.7 0.1 0.011 15.5 0.0 2.3 3 0 0 3 3 3 1 AAA domain SKI PF01202.17 CAR29449.1 - 0.0063 16.3 0.6 0.024 14.4 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase RNA_helicase PF00910.17 CAR29449.1 - 0.011 15.8 0.0 0.22 11.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.1 CAR29449.1 - 0.041 14.1 0.0 0.041 14.1 0.0 3.7 4 1 0 4 4 3 0 AAA domain IstB_IS21 PF01695.12 CAR29449.1 - 0.047 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF258 PF03193.11 CAR29449.1 - 0.058 12.5 0.3 0.14 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Aldedh PF00171.17 CAR29450.1 - 4.1e-162 539.6 0.0 4.8e-162 539.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 CAR29450.1 - 0.2 10.8 0.0 0.68 9.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) zf-UBR PF02207.15 CAR29451.1 - 1.2e-12 47.3 11.6 1.2e-12 47.3 8.1 2.7 2 1 1 3 3 3 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.24 CAR29451.1 - 6.1e-05 22.6 8.7 6.1e-05 22.6 6.0 2.9 2 1 0 2 2 2 1 PHD-finger MCM PF00493.18 CAR29452.1 - 2.9e-140 466.7 0.0 4.3e-140 466.2 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 CAR29452.1 - 9.7e-31 106.8 36.4 9.7e-31 106.8 25.3 4.4 5 0 0 5 5 5 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 CAR29452.1 - 9.2e-15 55.1 0.0 2.3e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 CAR29452.1 - 1.7e-08 33.9 0.0 3e-06 26.5 0.0 2.6 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CAR29452.1 - 7.6e-07 28.9 0.0 1.9e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CAR29452.1 - 0.00017 21.1 0.0 0.0015 18.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CAR29452.1 - 0.012 15.1 0.1 0.064 12.7 0.1 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain Nol1_Nop2_Fmu PF01189.12 CAR29453.1 - 4.6e-84 282.1 0.0 1.1e-66 225.1 0.0 2.2 1 1 1 2 2 2 2 NOL1/NOP2/sun family FtsJ PF01728.14 CAR29453.1 - 0.00047 20.2 0.0 0.00095 19.1 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 CAR29453.1 - 0.00071 20.1 0.0 0.0037 17.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain DGF-1_5 PF11038.3 CAR29453.1 - 0.0099 15.1 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 1 Dispersed gene family protein 1 of Trypanosoma cruzi region 5 Methyltransf_26 PF13659.1 CAR29453.1 - 0.024 14.6 0.0 0.05 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain UAF_Rrn10 PF05234.6 CAR29454.1 - 2.6e-46 156.5 0.0 3.1e-46 156.2 0.0 1.0 1 0 0 1 1 1 1 UAF complex subunit Rrn10 SpoA PF01052.15 CAR29454.1 - 0.088 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Surface presentation of antigens (SPOA) zf-CCHC PF00098.18 CAR29455.1 - 0.0097 15.8 1.8 0.014 15.2 1.3 1.3 1 0 0 1 1 1 1 Zinc knuckle T4_baseplate PF12322.3 CAR29455.1 - 0.028 13.6 0.6 0.038 13.2 0.4 1.2 1 0 0 1 1 1 0 T4 bacteriophage base plate protein PyrI_C PF02748.10 CAR29455.1 - 0.03 13.7 0.5 0.054 12.9 0.4 1.5 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-CCHC_4 PF14392.1 CAR29455.1 - 0.064 12.9 0.9 0.11 12.1 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-BED PF02892.10 CAR29455.1 - 0.5 10.1 4.2 1.2 8.9 2.9 1.7 1 1 0 1 1 1 0 BED zinc finger LSM PF01423.17 CAR29456.1 - 8.1e-17 60.5 0.3 1.1e-16 60.1 0.2 1.2 1 0 0 1 1 1 1 LSM domain GDI PF00996.13 CAR29457.1 - 3.4e-212 704.4 0.1 3.9e-212 704.3 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 CAR29457.1 - 0.012 15.5 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ABC_tran PF00005.22 CAR29458.1 - 1.6e-22 80.2 0.0 1.5e-12 47.9 0.0 3.1 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CAR29458.1 - 4.7e-06 26.7 3.9 0.0037 17.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 CAR29458.1 - 0.0015 18.4 0.1 0.45 10.4 0.0 2.4 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 CAR29458.1 - 0.0081 15.6 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CAR29458.1 - 0.089 12.9 0.1 0.65 10.1 0.0 2.3 2 1 0 2 2 2 0 AAA domain Miro PF08477.8 CAR29458.1 - 0.15 12.5 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein AAA_23 PF13476.1 CAR29458.1 - 0.29 11.4 0.7 0.47 10.7 0.1 1.5 2 0 0 2 2 2 0 AAA domain Aminotran_1_2 PF00155.16 CAR29459.1 - 5.2e-72 242.7 0.0 6.2e-72 242.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 CAR29459.1 - 0.025 13.3 0.0 0.037 12.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Cofilin_ADF PF00241.15 CAR29460.1 - 1.7e-08 34.4 0.1 1.9e-08 34.2 0.1 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Ribosomal_S13_N PF08069.7 CAR29461.1 - 1.6e-28 98.3 0.1 3.5e-28 97.2 0.1 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 CAR29461.1 - 7.7e-24 83.2 0.2 3.1e-23 81.3 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S15 Gly_transf_sug PF04488.10 CAR29462.1 - 2.5e-13 50.3 0.0 8.7e-13 48.5 0.0 1.9 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 CAR29462.1 - 0.00027 20.2 0.1 0.00069 18.8 0.0 1.8 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.2 CAR29462.1 - 0.013 14.0 0.0 0.056 11.9 0.0 1.9 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Isochorismatase PF00857.15 CAR29463.1 - 2.5e-25 89.4 0.0 3.4e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Hexokinase_1 PF00349.16 CAR29463.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Hexokinase NUC153 PF08159.7 CAR29466.1 - 2.2e-10 39.9 5.1 4.7e-10 38.8 3.5 1.6 1 0 0 1 1 1 1 NUC153 domain SNARE PF05739.14 CAR29467.1 - 0.00019 21.0 3.4 0.00019 21.0 2.3 3.6 4 0 0 4 4 4 2 SNARE domain V-SNARE_C PF12352.3 CAR29467.1 - 0.029 14.4 1.3 0.15 12.1 0.2 2.7 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus Ecl1 PF12855.2 CAR29468.1 - 3.6e-17 61.3 0.2 5.5e-17 60.7 0.2 1.3 1 0 0 1 1 1 1 Life-span regulatory factor zf-MYND PF01753.13 CAR29468.1 - 0.076 12.9 0.2 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 MYND finger zf-H2C2_2 PF13465.1 CAR29469.1 - 1.2e-12 47.4 14.8 7.5e-08 32.3 2.7 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 CAR29469.1 - 3.4e-08 33.3 18.2 7.1e-05 22.9 1.9 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CAR29469.1 - 0.00012 22.0 16.5 0.0051 17.0 1.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CAR29469.1 - 0.087 12.7 8.8 0.78 9.7 0.6 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CAR29469.1 - 0.2 11.8 3.4 2.5 8.3 0.6 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding TBPIP PF07106.8 CAR29470.1 - 5.4e-40 136.7 3.3 6.4e-40 136.4 2.3 1.0 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Prominin PF05478.6 CAR29470.1 - 0.0011 16.6 3.1 0.0013 16.3 2.2 1.0 1 0 0 1 1 1 1 Prominin Mnd1 PF03962.10 CAR29470.1 - 0.023 14.3 2.5 0.042 13.5 1.8 1.4 1 1 0 1 1 1 0 Mnd1 family Atg14 PF10186.4 CAR29470.1 - 0.027 13.4 1.7 0.036 13.0 1.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 CAR29470.1 - 0.08 12.5 1.5 0.11 12.0 1.0 1.3 1 0 0 1 1 1 0 IncA protein MarR_2 PF12802.2 CAR29470.1 - 0.095 12.3 0.1 9.9 5.9 0.0 2.6 3 0 0 3 3 3 0 MarR family DUF1539 PF07560.6 CAR29470.1 - 0.18 11.6 1.3 0.55 10.1 0.9 1.9 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1539) SYCE1 PF15233.1 CAR29470.1 - 0.44 10.4 8.4 0.5 10.2 4.7 1.8 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 Phasin PF05597.6 CAR29470.1 - 0.91 9.2 4.8 1.3 8.7 2.5 2.0 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF904 PF06005.7 CAR29470.1 - 4.6 7.6 8.6 7.7 6.8 4.9 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF904) Uricase PF01014.13 CAR29471.1 - 3.7e-69 231.1 0.5 4.8e-35 120.6 0.4 2.0 2 0 0 2 2 2 2 Uricase DUF1279 PF06916.8 CAR29472.1 - 6.4e-26 90.4 0.0 9.9e-26 89.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Transketolase_N PF00456.16 CAR29472.1 - 0.054 12.2 0.2 0.079 11.7 0.2 1.1 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain Ribosomal_L24e PF01246.15 CAR29473.1 - 4.4e-33 112.9 0.2 4.4e-33 112.9 0.2 2.0 2 1 0 2 2 2 1 Ribosomal protein L24e DUF4557 PF15101.1 CAR29473.1 - 3.6 7.3 6.5 4.3 7.1 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Ribosomal_L7Ae PF01248.21 CAR29474.1 - 2.1e-24 84.8 0.1 2.3e-24 84.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF2838 PF10998.3 CAR29475.1 - 6.6e-43 145.1 13.8 6.6e-43 145.1 9.6 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF2838) PPR_2 PF13041.1 CAR29476.1 - 5.2e-17 61.5 0.4 1.5e-09 37.6 0.0 4.2 3 1 1 4 4 4 2 PPR repeat family PPR_3 PF13812.1 CAR29476.1 - 2.5e-09 36.6 3.6 0.022 14.9 0.0 6.0 8 0 0 8 8 8 3 Pentatricopeptide repeat domain PPR PF01535.15 CAR29476.1 - 1.1e-08 34.4 0.0 0.00045 20.0 0.0 3.6 3 0 0 3 3 3 2 PPR repeat PPR_1 PF12854.2 CAR29476.1 - 1.2e-05 24.6 0.0 0.033 13.6 0.0 3.0 2 0 0 2 2 2 2 PPR repeat TPR_7 PF13176.1 CAR29476.1 - 0.021 14.6 1.0 0.062 13.1 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat KLRAQ PF10205.4 CAR29476.1 - 0.73 9.9 6.8 5.3 7.1 1.8 2.8 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein Cgr1 PF03879.9 CAR29477.1 - 2.3e-33 114.6 31.9 2.7e-33 114.3 22.1 1.0 1 0 0 1 1 1 1 Cgr1 family DNA_pol3_a_NII PF11490.3 CAR29477.1 - 1.7 8.2 9.8 2.3 7.8 6.5 1.5 1 1 0 1 1 1 0 DNA polymerase III polC-type N-terminus II Vma12 PF11712.3 CAR29477.1 - 9 5.9 6.4 13 5.5 4.4 1.3 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF706 PF05153.10 CAR29478.1 - 1.3e-119 398.1 9.0 1.6e-119 397.8 6.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 CAR29478.1 - 0.00062 19.7 2.8 0.47 10.4 0.0 3.2 2 1 0 3 3 3 2 HD domain GET2 PF08690.5 CAR29478.1 - 0.22 10.7 3.2 0.33 10.1 2.2 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 Clc-like PF07062.7 CAR29478.1 - 0.65 9.2 3.1 0.83 8.8 0.1 2.2 1 1 1 2 2 2 0 Clc-like Glyco_hydro_17 PF00332.13 CAR29479.1 - 1.8e-05 23.9 0.4 0.015 14.3 0.1 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 Glyco_hydro_63 PF03200.11 CAR29480.1 - 6.4e-217 722.1 1.6 4.6e-216 719.3 1.1 1.8 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Rrn6 PF10214.4 CAR29481.1 - 2.6e-126 422.6 16.9 3.9e-126 422.0 11.7 1.3 1 1 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Trp_syntA PF00290.15 CAR29482.1 - 1.3e-95 318.7 0.3 2.2e-95 318.0 0.2 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 CAR29482.1 - 2.7e-43 148.3 0.8 5.2e-43 147.4 0.4 1.6 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme BtpA PF03437.10 CAR29482.1 - 0.02 14.1 0.5 0.29 10.3 0.0 2.4 2 0 0 2 2 2 0 BtpA family Med3 PF11593.3 CAR29483.1 - 7.9e-44 150.4 30.7 9.6e-42 143.5 4.4 8.0 1 1 3 4 4 4 2 Mediator complex subunit 3 fungal RR_TM4-6 PF06459.7 CAR29483.1 - 1.3 8.9 18.3 0.24 11.2 3.1 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Formyl_trans_N PF00551.14 CAR29485.1 - 7e-33 113.6 0.0 1e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 CAR29485.1 - 2.3e-08 34.0 0.0 4.8e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Acyltransferase PF01553.16 CAR29486.1 - 7.3e-10 38.4 0.0 4.5e-09 35.8 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase DUF3816 PF12822.2 CAR29486.1 - 0.011 15.6 5.4 0.02 14.8 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) MarR_2 PF12802.2 CAR29486.1 - 0.054 13.1 0.7 0.13 11.9 0.5 1.6 1 0 0 1 1 1 0 MarR family YesK PF14150.1 CAR29486.1 - 6.2 6.9 9.7 0.25 11.4 0.7 2.9 2 1 1 3 3 3 0 YesK-like protein FYVE PF01363.16 CAR29487.1 - 2.4e-14 52.9 4.1 7.1e-14 51.4 2.8 1.9 1 0 0 1 1 1 1 FYVE zinc finger STT3 PF02516.9 CAR29488.1 - 7.3e-137 457.2 47.6 1.4e-136 456.3 33.0 1.4 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit DUF1367 PF07105.6 CAR29489.1 - 0.096 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1367) DUF3635 PF12330.3 CAR29490.1 - 2.7e-20 72.2 0.0 8.3e-20 70.6 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3635) CHD5 PF04420.9 CAR29491.1 - 4e-45 153.3 0.9 4.8e-45 153.1 0.1 1.5 2 0 0 2 2 2 1 CHD5-like protein DUF3584 PF12128.3 CAR29491.1 - 0.008 13.5 2.1 0.011 13.1 1.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Ctr PF04145.10 CAR29491.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.7 2 0 0 2 2 2 0 Ctr copper transporter family Ureide_permease PF07168.6 CAR29491.1 - 0.12 11.0 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Ureide permease CK_II_beta PF01214.13 CAR29492.1 - 3.9e-71 238.3 0.1 6.1e-71 237.7 0.1 1.3 1 1 0 1 1 1 1 Casein kinase II regulatory subunit HSCB_C PF07743.8 CAR29493.1 - 4.9e-17 62.1 0.9 1.2e-16 60.9 0.6 1.7 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 CAR29493.1 - 5.4e-10 38.8 0.1 1.4e-09 37.5 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain DUF1376 PF07120.6 CAR29493.1 - 0.048 13.7 0.0 0.22 11.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1376) UVR PF02151.14 CAR29493.1 - 0.05 13.1 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 UvrB/uvrC motif NifW PF03206.9 CAR29493.1 - 0.078 13.0 0.3 2 8.5 0.0 2.8 2 1 1 3 3 3 0 Nitrogen fixation protein NifW ATE_C PF04377.10 CAR29494.1 - 3.2e-42 143.6 0.8 7.4e-42 142.4 0.4 1.7 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 CAR29494.1 - 9.6e-24 82.9 3.2 1.3e-23 82.5 1.4 1.9 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus WD40 PF00400.27 CAR29496.1 - 1.9e-40 135.3 13.9 4.6e-11 42.1 0.0 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat Hira PF07569.6 CAR29496.1 - 1.2e-08 34.4 0.0 4e-08 32.7 0.0 1.9 2 0 0 2 2 2 1 TUP1-like enhancer of split HIRA_B PF09453.5 CAR29496.1 - 3.5e-08 32.7 0.0 1.2e-07 31.0 0.0 2.1 1 0 0 1 1 1 1 HIRA B motif eIF2A PF08662.6 CAR29496.1 - 5.9e-05 22.8 0.0 1.3 8.7 0.0 4.4 4 1 1 5 5 5 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 CAR29496.1 - 0.00083 18.9 0.3 1.6 8.4 0.0 3.7 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 CAR29496.1 - 0.015 14.4 0.0 0.046 12.8 0.0 1.9 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal Aconitase PF00330.15 CAR29497.1 - 2.4e-190 632.9 0.7 3e-190 632.6 0.5 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CAR29497.1 - 2.9e-47 160.0 0.0 1e-46 158.2 0.0 1.9 2 0 0 2 2 2 1 Aconitase C-terminal domain SH3_1 PF00018.23 CAR29498.1 - 3e-36 122.5 5.4 4.2e-12 45.2 0.0 4.3 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.1 CAR29498.1 - 1.4e-33 114.2 8.0 1.4e-12 46.9 0.2 4.0 4 0 0 4 4 4 3 Variant SH3 domain SHD1 PF03983.7 CAR29498.1 - 2.9e-33 113.3 0.0 5.3e-33 112.4 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.12 CAR29498.1 - 5.7e-29 99.3 0.0 2.2e-09 36.6 0.0 4.7 4 0 0 4 4 4 3 Variant SH3 domain SH3_3 PF08239.6 CAR29498.1 - 0.025 14.7 1.1 15 5.9 0.0 3.3 3 0 0 3 3 3 0 Bacterial SH3 domain SAM_1 PF00536.25 CAR29498.1 - 0.096 12.8 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF962 PF06127.6 CAR29499.1 - 2.3e-24 85.1 5.2 1.3e-23 82.6 3.6 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DUF1056 PF06341.6 CAR29499.1 - 0.09 12.8 1.9 0.23 11.5 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1056) Proteasome PF00227.21 CAR29500.1 - 3.5e-42 143.8 0.0 5e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CAR29500.1 - 1.9e-15 55.8 0.1 3.4e-15 55.0 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Rsc14 PF08586.5 CAR29501.1 - 5.7e-39 132.6 0.3 9.1e-39 132.0 0.2 1.3 1 0 0 1 1 1 1 RSC complex, Rsc14/Ldb7 subunit PAP_RNA-bind PF04926.10 CAR29501.1 - 0.0012 18.3 0.5 0.3 10.6 0.1 2.1 2 0 0 2 2 2 2 Poly(A) polymerase predicted RNA binding domain zf-BED PF02892.10 CAR29501.1 - 0.012 15.3 1.2 0.024 14.3 0.9 1.5 1 0 0 1 1 1 0 BED zinc finger zf-AN1 PF01428.11 CAR29501.1 - 0.013 15.3 1.6 0.026 14.4 1.1 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger ERG4_ERG24 PF01222.12 CAR29502.1 - 3.9e-180 599.0 30.9 4.4e-180 598.8 21.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family CytoC_RC PF02276.13 CAR29502.1 - 0.021 13.9 0.1 0.031 13.3 0.1 1.1 1 0 0 1 1 1 0 Photosynthetic reaction centre cytochrome C subunit CMV_1a_C PF12503.3 CAR29502.1 - 1.5 8.6 0.0 1.5 8.6 0.0 2.6 3 0 0 3 3 3 0 Cucumber mosaic virus 1a protein C terminal Fungal_trans PF04082.13 CAR29504.1 - 1.5e-29 102.7 6.7 1.5e-29 102.7 4.7 2.2 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR29504.1 - 9.9e-08 31.7 10.8 2.5e-07 30.4 7.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med9 PF07544.8 CAR29504.1 - 0.047 13.4 1.7 0.33 10.7 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 PUF PF00806.14 CAR29505.1 - 8.1e-61 198.2 14.2 4.6e-09 35.2 0.2 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat E1-E2_ATPase PF00122.15 CAR29506.1 - 2.5e-63 213.2 4.1 2.5e-63 213.2 2.9 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CAR29506.1 - 9.3e-25 88.3 0.0 1.6e-24 87.5 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CAR29506.1 - 7.1e-14 52.4 0.0 2e-13 50.9 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CAR29506.1 - 1.4e-10 40.4 0.0 3.7e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CAR29506.1 - 0.0017 18.0 0.1 0.0033 17.0 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CAR29506.1 - 0.0096 15.8 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit ADH_N PF08240.7 CAR29507.1 - 2.7e-20 72.1 7.6 4.4e-20 71.4 5.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CAR29507.1 - 1.1e-16 60.5 0.0 2.1e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CAR29507.1 - 4.8e-05 22.5 0.0 8.6e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 CAR29507.1 - 0.0046 16.5 0.0 0.0083 15.7 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 CAR29507.1 - 0.25 10.9 1.2 1.1 8.9 0.9 1.8 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain tRNA_int_endo PF01974.12 CAR29508.1 - 2.1e-18 65.8 0.0 5.8e-18 64.4 0.0 1.7 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain YebF PF13995.1 CAR29508.1 - 0.067 13.2 0.1 0.17 11.9 0.0 1.6 2 0 0 2 2 2 0 YebF-like protein E1-E2_ATPase PF00122.15 CAR29509.1 - 3.3e-62 209.5 1.5 3.3e-62 209.5 1.1 2.3 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CAR29509.1 - 6.2e-37 126.8 3.9 6.2e-37 126.8 2.7 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CAR29509.1 - 1.9e-24 87.2 0.0 1.1e-23 84.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CAR29509.1 - 4.4e-15 55.3 0.0 1.3e-14 53.9 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CAR29509.1 - 1.4e-11 44.8 0.0 5.1e-11 43.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CAR29509.1 - 2.3e-11 43.0 0.0 8.1e-11 41.2 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CAR29509.1 - 4e-05 23.3 5.9 0.00032 20.3 0.9 3.1 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF3325 PF11804.3 CAR29509.1 - 0.097 12.6 0.0 0.097 12.6 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3325) TMF_TATA_bd PF12325.3 CAR29510.1 - 0.001 18.7 0.2 0.001 18.7 0.1 2.9 2 1 0 3 3 3 1 TATA element modulatory factor 1 TATA binding DUF2450 PF10475.4 CAR29510.1 - 0.002 17.0 5.1 0.003 16.5 1.3 2.0 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) DASH_Dad3 PF08656.5 CAR29510.1 - 0.017 14.7 0.4 0.017 14.7 0.3 3.3 2 1 2 4 4 4 0 DASH complex subunit Dad3 DUF1978 PF09321.5 CAR29510.1 - 0.023 14.1 5.8 0.99 8.7 2.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1978) VPS9 PF02204.13 CAR29510.1 - 0.074 13.0 1.0 12 5.9 0.0 2.8 2 1 0 2 2 2 0 Vacuolar sorting protein 9 (VPS9) domain Imm46 PF15585.1 CAR29510.1 - 0.082 12.9 0.3 1.3 9.0 0.0 2.4 1 1 2 3 3 3 0 Immunity protein 46 Cor1 PF04803.7 CAR29510.1 - 0.09 12.5 4.7 0.15 11.8 0.1 2.9 3 1 0 3 3 3 0 Cor1/Xlr/Xmr conserved region DUF1664 PF07889.7 CAR29510.1 - 0.55 10.0 6.4 0.23 11.2 0.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.5 CAR29510.1 - 0.56 10.3 9.4 6.2 6.9 0.1 2.9 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Occludin_ELL PF07303.8 CAR29510.1 - 1 10.1 3.8 18 6.1 0.1 3.3 2 1 0 3 3 3 0 Occludin homology domain Sec34 PF04136.10 CAR29510.1 - 1.3 8.7 10.6 0.15 11.7 1.8 2.8 2 1 1 3 3 3 0 Sec34-like family NPV_P10 PF05531.7 CAR29510.1 - 1.6 9.0 8.6 0.73 10.1 1.8 2.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Mod_r PF07200.8 CAR29510.1 - 2 8.3 9.0 1.6 8.5 2.9 2.4 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein V_ATPase_I PF01496.14 CAR29510.1 - 2.1 6.0 7.8 0.78 7.5 3.2 1.7 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Takusan PF04822.8 CAR29510.1 - 2.6 7.8 11.1 0.85 9.4 1.4 3.1 2 1 1 3 3 3 0 Takusan WD40 PF00400.27 CAR29511.1 - 7.9e-20 69.9 5.3 2.8e-08 33.3 0.0 5.3 5 1 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 CAR29511.1 - 0.0024 17.6 0.0 2.5 7.7 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A CPSF_A PF03178.10 CAR29511.1 - 0.032 13.3 0.0 1.1 8.2 0.0 2.5 2 1 0 2 2 2 0 CPSF A subunit region Rep_fac-A_C PF08646.5 CAR29512.1 - 7.6e-56 187.8 0.5 1.1e-52 177.5 0.3 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 CAR29512.1 - 5.5e-15 54.9 0.1 3.3e-07 30.0 0.0 4.4 4 0 0 4 4 4 3 OB-fold nucleic acid binding domain Rep-A_N PF04057.7 CAR29512.1 - 0.00025 20.7 0.5 0.00074 19.2 0.0 2.1 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain BRCA-2_OB1 PF09103.5 CAR29512.1 - 0.016 14.9 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 Fungal_trans PF04082.13 CAR29513.1 - 6.1e-05 22.0 0.7 6.1e-05 22.0 0.5 2.2 2 1 1 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR29513.1 - 0.00085 19.1 6.4 0.0016 18.3 4.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 CAR29514.1 - 5.5e-31 105.3 0.3 9.8e-06 25.2 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 CAR29514.1 - 1.1e-06 28.4 0.2 0.00088 19.0 0.1 3.0 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 CAR29515.1 - 2.3e-17 62.1 3.7 1.6e-09 37.2 0.2 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 CAR29515.1 - 0.012 13.9 0.0 0.026 12.8 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain EMP24_GP25L PF01105.19 CAR29516.1 - 4.7e-49 166.5 0.9 5.8e-49 166.2 0.6 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD 3Beta_HSD PF01073.14 CAR29518.1 - 8.8e-83 277.2 0.0 1.1e-82 276.9 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CAR29518.1 - 8.7e-29 100.6 0.0 1.1e-28 100.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CAR29518.1 - 6.6e-15 54.7 0.0 2.1e-14 53.0 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 CAR29518.1 - 5.1e-11 42.0 0.0 9.2e-11 41.1 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 CAR29518.1 - 1.8e-07 31.3 0.0 2.8e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 CAR29518.1 - 1.2e-05 24.3 0.0 2.8e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 CAR29518.1 - 1.8e-05 24.1 0.0 2.9e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 CAR29518.1 - 0.00026 20.9 0.0 0.00089 19.2 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CAR29518.1 - 0.00048 19.8 0.0 0.0025 17.5 0.0 2.0 1 1 0 1 1 1 1 KR domain N6-adenineMlase PF10237.4 CAR29519.1 - 9.7e-56 187.8 0.0 1.4e-55 187.4 0.0 1.2 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase DUF4456 PF14644.1 CAR29519.1 - 0.048 12.8 3.4 0.071 12.3 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) B-block_TFIIIC PF04182.7 CAR29520.1 - 1.3e-15 56.9 0.2 8.2e-15 54.4 0.0 2.3 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC RPA_C PF08784.6 CAR29520.1 - 0.13 12.6 0.2 21 5.5 0.0 3.1 3 0 0 3 3 3 0 Replication protein A C terminal Vps8 PF12816.2 CAR29521.1 - 3.7e-60 202.5 0.3 3.7e-60 202.5 0.2 2.1 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 CAR29521.1 - 0.00018 21.1 8.5 0.0016 18.0 0.4 3.4 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 CAR29521.1 - 0.00092 18.9 1.3 0.00092 18.9 0.9 2.5 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 CAR29521.1 - 0.002 17.7 2.9 0.0062 16.2 2.0 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CAR29521.1 - 0.0045 16.6 1.2 0.014 15.0 0.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CAR29521.1 - 0.012 15.7 5.5 0.021 14.9 2.1 2.6 2 1 0 2 2 2 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CAR29521.1 - 0.013 15.4 2.1 0.029 14.4 0.8 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 CAR29521.1 - 0.053 13.2 0.7 0.15 11.7 0.5 1.7 1 0 0 1 1 1 0 PHD-finger zf-Apc11 PF12861.2 CAR29521.1 - 2.5 7.9 6.0 0.45 10.3 0.2 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger IR1-M PF12185.3 CAR29522.1 - 0.45 10.2 2.9 1.1 9.0 0.1 2.5 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain EF1_GNE PF00736.14 CAR29523.1 - 2e-30 104.2 2.0 4.5e-30 103.1 1.4 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 CAR29523.1 - 2.3e-12 46.8 8.2 6.2e-12 45.4 5.7 1.8 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 CAR29523.1 - 0.01 16.2 0.0 0.024 15.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CAR29523.1 - 0.015 15.2 1.5 0.2 11.6 0.1 2.7 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CAR29523.1 - 0.042 13.7 0.0 0.14 12.0 0.0 1.8 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain DNA_pol3_a_NII PF11490.3 CAR29523.1 - 0.21 11.2 3.8 7.1 6.2 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II FAM110_C PF14160.1 CAR29523.1 - 0.23 12.3 1.5 0.43 11.5 1.1 1.5 1 0 0 1 1 1 0 Centrosome-associated C terminus eIF-3c_N PF05470.7 CAR29523.1 - 0.51 8.3 5.8 0.57 8.2 4.0 1.2 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SNF5 PF04855.7 CAR29525.1 - 1.8e-65 220.8 1.0 3.2e-38 131.5 0.0 2.2 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 RTX_C PF08339.5 CAR29526.1 - 0.0071 16.0 1.8 0.02 14.6 1.2 1.9 1 1 0 1 1 1 1 RTX C-terminal domain DUF2200 PF09966.4 CAR29526.1 - 0.049 13.5 0.7 0.12 12.2 0.3 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2200) HTH_32 PF13565.1 CAR29526.1 - 0.13 13.1 0.5 7.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain Cnl2_NKP2 PF09447.5 CAR29526.1 - 0.14 11.8 6.4 0.067 12.8 1.5 2.6 3 1 0 3 3 3 0 Cnl2/NKP2 family protein PqqD PF05402.7 CAR29526.1 - 0.24 11.4 1.3 13 5.8 0.4 2.8 2 1 1 3 3 3 0 Coenzyme PQQ synthesis protein D (PqqD) Ribosomal_L50 PF10501.4 CAR29526.1 - 0.5 10.3 6.6 3 7.8 0.1 2.2 1 1 1 2 2 2 0 Ribosomal subunit 39S dCMP_cyt_deam_1 PF00383.17 CAR29527.1 - 1.6e-07 30.9 0.0 3.1e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Telomerase_RBD PF12009.3 CAR29528.1 - 1.7e-29 102.4 5.9 5.2e-29 100.8 4.1 1.9 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 CAR29528.1 - 1.2e-07 31.2 0.0 3.5e-07 29.8 0.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AIP3 PF03915.8 CAR29529.1 - 7.6e-148 492.9 17.7 7.6e-148 492.9 12.3 2.1 2 1 0 2 2 2 1 Actin interacting protein 3 LMBR1 PF04791.11 CAR29529.1 - 0.61 8.5 2.6 1.4 7.3 1.8 1.7 1 0 0 1 1 1 0 LMBR1-like membrane protein Mus7 PF09462.5 CAR29530.1 - 1.3e-23 83.6 31.1 8e-22 77.8 2.6 3.2 2 1 1 4 4 4 2 Mus7/MMS22 family Myb_DNA-bind_6 PF13921.1 CAR29531.1 - 1.8e-05 24.7 2.2 0.00016 21.7 0.2 2.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CAR29531.1 - 0.012 15.6 0.1 0.037 14.0 0.1 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain E_Pc_C PF06752.7 CAR29531.1 - 0.11 11.9 6.3 0.21 11.0 4.3 1.4 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus Cullin PF00888.17 CAR29532.1 - 2.8e-100 336.5 26.0 2.8e-100 336.5 18.1 1.3 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 CAR29532.1 - 3e-20 71.7 2.2 3e-20 71.7 1.6 2.4 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF2674 PF10879.3 CAR29532.1 - 0.032 13.9 0.1 0.17 11.6 0.1 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2674) zf-CCCH PF00642.19 CAR29533.1 - 9e-10 38.0 2.0 2e-09 36.9 1.4 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.1 CAR29533.1 - 1.9e-09 37.3 10.3 3.9e-09 36.3 7.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CAR29533.1 - 5.1e-09 35.6 6.4 9.3e-09 34.8 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAR29533.1 - 5.4e-08 32.4 9.6 1.1e-07 31.3 6.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CAR29533.1 - 2.6e-07 30.3 7.9 5.9e-07 29.2 5.5 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CAR29533.1 - 1.3e-06 27.9 9.9 3e-06 26.7 6.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CAR29533.1 - 9.6e-05 22.0 4.9 0.00029 20.4 3.2 2.2 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CAR29533.1 - 0.001 18.8 8.6 0.001 18.8 6.0 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING PolC_DP2 PF03833.8 CAR29533.1 - 0.05 11.2 3.6 0.063 10.9 2.5 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-P11 PF03854.9 CAR29533.1 - 0.12 11.8 4.4 0.25 10.8 3.0 1.5 1 0 0 1 1 1 0 P-11 zinc finger Prok-RING_4 PF14447.1 CAR29533.1 - 0.19 11.3 5.6 0.46 10.0 3.9 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 CAR29533.1 - 0.32 10.8 4.3 0.76 9.6 3.0 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 CAR29533.1 - 0.34 11.0 7.1 1.3 9.1 4.9 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger Pex24p PF06398.6 CAR29534.1 - 1.5e-91 306.8 11.2 2.1e-91 306.4 7.8 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Ribosomal_L38e PF01781.13 CAR29535.1 - 3.1e-28 97.3 2.1 3.5e-28 97.1 1.4 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family TFIIF_beta PF02270.10 CAR29536.1 - 1.2e-93 313.8 13.9 1.7e-93 313.4 9.7 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit DUF2252 PF10009.4 CAR29536.1 - 0.17 10.7 5.8 0.037 12.9 1.6 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2252) Ribosomal_S25 PF03297.10 CAR29536.1 - 0.34 10.9 4.2 0.12 12.4 0.9 1.8 2 0 0 2 2 2 0 S25 ribosomal protein V_ATPase_I PF01496.14 CAR29536.1 - 1.2 6.8 3.7 1.7 6.3 2.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prp18 PF02840.10 CAR29537.1 - 5.5e-44 149.5 0.0 1.3e-43 148.3 0.0 1.6 1 1 0 1 1 1 1 Prp18 domain EIIC-GAT PF03611.9 CAR29537.1 - 0.11 11.2 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 PTS system sugar-specific permease component KH_1 PF00013.24 CAR29537.1 - 0.2 11.3 0.7 0.35 10.5 0.1 1.7 2 0 0 2 2 2 0 KH domain DUF4112 PF13430.1 CAR29538.1 - 5.9e-30 103.3 0.4 8e-30 102.8 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) Neur_chan_memb PF02932.11 CAR29538.1 - 0.069 13.0 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM220 PF15487.1 CAR29538.1 - 4.3 6.6 6.8 6.9 5.9 4.7 1.2 1 0 0 1 1 1 0 FAM220 family CTP_transf_2 PF01467.21 CAR29539.1 - 1.8e-15 57.3 0.1 4.2e-11 43.1 0.0 2.5 2 1 0 2 2 2 2 Cytidylyltransferase FAD_syn PF06574.7 CAR29539.1 - 0.0077 15.8 0.6 3.4 7.2 0.1 3.2 3 0 0 3 3 3 1 FAD synthetase HABP4_PAI-RBP1 PF04774.10 CAR29540.1 - 0.00021 21.7 0.3 0.00031 21.2 0.2 1.3 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family CTP_transf_2 PF01467.21 CAR29541.1 - 7.4e-36 123.5 0.0 2.2e-35 122.0 0.0 1.7 2 0 0 2 2 2 1 Cytidylyltransferase ComJ PF11033.3 CAR29542.1 - 0.035 13.7 0.2 0.047 13.3 0.1 1.3 1 0 0 1 1 1 0 Competence protein J (ComJ) PALP PF00291.20 CAR29543.1 - 1.9e-61 207.9 0.0 2.3e-61 207.7 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PWI PF01480.12 CAR29544.1 - 0.0076 16.3 0.1 0.034 14.2 0.1 2.1 1 0 0 1 1 1 1 PWI domain Mucin PF01456.12 CAR29544.1 - 0.033 13.9 9.5 0.059 13.1 6.6 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.3 CAR29544.1 - 0.11 12.2 6.0 0.22 11.2 4.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 CAR29544.1 - 0.17 9.7 6.2 0.24 9.3 4.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Abhydrolase_6 PF12697.2 CAR29546.1 - 1e-20 74.6 0.0 1.5e-20 74.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAR29546.1 - 1.9e-09 37.4 0.0 5e-09 36.0 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CAR29546.1 - 3e-08 33.5 0.0 3.9e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 CAR29546.1 - 7.5e-05 22.4 0.0 0.00012 21.7 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 CAR29546.1 - 0.00017 21.8 0.0 0.00026 21.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain DUF726 PF05277.7 CAR29546.1 - 0.013 14.3 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) FSH1 PF03959.8 CAR29546.1 - 0.061 12.7 0.0 0.65 9.3 0.0 2.3 2 1 0 3 3 3 0 Serine hydrolase (FSH1) BAAT_C PF08840.6 CAR29546.1 - 0.08 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Lipase_3 PF01764.20 CAR29546.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.8 CAR29546.1 - 0.13 11.8 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 CAR29546.1 - 0.15 11.8 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase TGS PF02824.16 CAR29549.1 - 1.5e-19 69.5 0.0 3.5e-19 68.3 0.0 1.7 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 CAR29549.1 - 3.1e-18 65.8 0.3 9.8e-18 64.2 0.2 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CAR29549.1 - 3.1e-13 49.2 0.0 5.9e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 CAR29549.1 - 0.0017 18.8 0.3 0.0049 17.3 0.1 2.0 2 1 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 CAR29549.1 - 0.0037 17.1 0.5 1.1 9.0 0.0 2.5 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.11 CAR29549.1 - 0.0066 15.5 0.1 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 AIG1 family MCM PF00493.18 CAR29549.1 - 0.0082 14.9 0.3 0.019 13.8 0.0 1.6 2 0 0 2 2 2 1 MCM2/3/5 family SRPRB PF09439.5 CAR29549.1 - 0.018 14.2 0.2 0.11 11.6 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Ras PF00071.17 CAR29549.1 - 0.11 11.9 0.4 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Ras family ETF PF01012.16 CAR29550.1 - 3.4e-34 117.9 0.1 4.6e-34 117.5 0.1 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Mvb12 PF09452.5 CAR29551.1 - 4.2e-23 81.3 0.1 4.7e-23 81.1 0.1 1.0 1 0 0 1 1 1 1 ESCRT-I subunit Mvb12 3-HAO PF06052.7 CAR29552.1 - 1.8e-63 212.4 0.0 2.1e-63 212.2 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 CAR29552.1 - 0.0028 17.1 0.0 0.0048 16.3 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Nudix_N_2 PF14803.1 CAR29552.1 - 0.009 15.6 0.5 2.1 8.1 0.1 2.6 2 0 0 2 2 2 2 Nudix N-terminal Rpr2 PF04032.11 CAR29552.1 - 0.013 15.3 0.4 0.073 12.9 0.3 2.0 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-RanBP PF00641.13 CAR29552.1 - 1.4 8.0 4.5 6.1 6.0 0.2 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Aldolase_II PF00596.16 CAR29553.1 - 1e-39 136.0 0.0 1.2e-39 135.8 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain LSM PF01423.17 CAR29554.1 - 1.2e-09 37.5 0.0 2e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 LSM domain DUF3255 PF11631.3 CAR29554.1 - 0.014 15.0 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3255) AAA_17 PF13207.1 CAR29555.1 - 4.7e-05 24.1 0.1 0.00014 22.6 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CAR29555.1 - 0.0015 18.5 0.0 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 CAR29555.1 - 0.0019 18.0 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CAR29555.1 - 0.0037 16.3 0.0 0.0066 15.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin PRK PF00485.13 CAR29555.1 - 0.0058 16.2 0.0 0.0095 15.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.1 CAR29555.1 - 0.014 15.5 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 CAR29555.1 - 0.017 15.2 0.0 0.029 14.5 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.14 CAR29555.1 - 0.025 13.7 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain RNA_helicase PF00910.17 CAR29555.1 - 0.033 14.3 0.0 0.056 13.6 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.1 CAR29555.1 - 0.051 13.8 0.0 0.12 12.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CAR29555.1 - 0.053 13.8 0.0 0.16 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 CAR29555.1 - 0.057 12.8 0.0 0.077 12.4 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MobB PF03205.9 CAR29555.1 - 0.062 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 CAR29555.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Acyl_CoA_thio PF02551.10 CAR29556.1 - 3.5e-31 107.5 0.1 1.7e-25 89.1 0.1 3.2 2 1 0 2 2 2 2 Acyl-CoA thioesterase 4HBT_3 PF13622.1 CAR29556.1 - 7e-27 94.7 0.0 9.2e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Glyco_transf_64 PF09258.5 CAR29556.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 64 domain FTHFS PF01268.14 CAR29557.1 - 8e-257 852.6 0.3 1.2e-256 852.1 0.2 1.3 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 CAR29557.1 - 2.9e-61 205.2 0.3 6.3e-61 204.1 0.0 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 CAR29557.1 - 5e-37 126.5 1.1 1.1e-36 125.4 0.8 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AdoHcyase_NAD PF00670.16 CAR29557.1 - 0.0075 16.1 0.6 0.23 11.2 0.3 2.9 2 1 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Dala_Dala_lig_C PF07478.8 CAR29557.1 - 0.076 12.3 0.2 0.22 10.8 0.0 1.8 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus GTP_EFTU PF00009.22 CAR29557.1 - 0.099 12.0 0.2 0.29 10.5 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain GSHPx PF00255.14 CAR29557.1 - 0.13 11.6 0.0 0.35 10.2 0.0 1.7 1 0 0 1 1 1 0 Glutathione peroxidase Rotamase PF00639.16 CAR29558.1 - 1.3e-27 96.3 0.1 1.9e-27 95.8 0.1 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 CAR29558.1 - 1.5e-21 76.7 0.0 2.3e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 CAR29558.1 - 1.8e-09 38.2 0.0 2.5e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 CAR29558.1 - 8.2e-07 28.7 0.9 1.4e-06 27.9 0.6 1.4 1 0 0 1 1 1 1 WW domain Rhodanese PF00581.15 CAR29559.1 - 1.8e-10 41.1 0.0 2.1e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain CTP_transf_2 PF01467.21 CAR29560.1 - 4.1e-22 78.9 0.2 8.9e-22 77.8 0.0 1.7 2 0 0 2 2 2 1 Cytidylyltransferase ILVD_EDD PF00920.16 CAR29561.1 - 2.5e-201 669.6 0.1 2.8e-201 669.4 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family WD40 PF00400.27 CAR29562.1 - 1.8e-61 201.9 25.3 2e-09 36.9 0.0 11.2 12 0 0 12 12 12 10 WD domain, G-beta repeat PMT PF02366.13 CAR29563.1 - 1.8e-86 289.4 16.1 1.8e-86 289.4 11.2 2.2 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CAR29563.1 - 2.7e-19 69.4 0.6 4.5e-19 68.7 0.4 1.4 1 0 0 1 1 1 1 MIR domain Thi4 PF01946.12 CAR29565.1 - 5.4e-95 316.8 0.1 6.4e-95 316.6 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 CAR29565.1 - 1.4e-06 27.5 0.3 3.6e-06 26.1 0.1 1.7 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CAR29565.1 - 1.4e-05 24.8 0.1 0.00013 21.7 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 CAR29565.1 - 3.3e-05 23.8 0.0 7.5e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 CAR29565.1 - 0.00013 21.0 0.1 0.0002 20.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 CAR29565.1 - 0.00037 19.4 1.1 0.0048 15.7 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 CAR29565.1 - 0.0028 17.5 0.0 0.026 14.4 0.1 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CAR29565.1 - 0.0076 14.7 0.1 0.017 13.6 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 CAR29565.1 - 0.027 14.5 0.1 0.07 13.1 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TPR_16 PF13432.1 CAR29566.1 - 2.9e-05 24.5 0.0 0.55 10.9 0.0 3.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 CAR29566.1 - 0.00018 21.8 0.0 2 9.2 0.0 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 CAR29566.1 - 0.00061 19.3 9.6 0.06 13.0 0.0 5.2 6 1 1 7 7 7 2 TPR repeat TPR_19 PF14559.1 CAR29566.1 - 0.0024 18.1 0.4 2.1 8.7 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat PPTA PF01239.17 CAR29566.1 - 0.0049 16.1 0.5 0.043 13.1 0.0 2.7 2 0 0 2 2 2 1 Protein prenyltransferase alpha subunit repeat TPR_2 PF07719.12 CAR29566.1 - 0.025 14.4 2.8 20 5.3 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat SUI1 PF01253.17 CAR29567.1 - 2.5e-21 75.2 2.0 4.4e-21 74.4 1.4 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 IF-2 PF11987.3 CAR29567.1 - 0.025 14.4 1.1 0.036 13.9 0.2 1.7 2 0 0 2 2 2 0 Translation-initiation factor 2 Img2 PF05046.9 CAR29567.1 - 0.84 9.8 3.4 28 5.0 2.4 2.3 1 1 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) RNase_PH PF01138.16 CAR29569.1 - 3.7e-28 98.4 0.1 5.9e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CAR29569.1 - 0.0002 21.2 0.2 0.00043 20.1 0.1 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Mannosyl_trans PF05007.8 CAR29570.1 - 7.9e-85 284.6 18.3 1.3e-84 283.9 12.7 1.4 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 CAR29570.1 - 3.7e-11 42.4 11.7 3.7e-11 42.4 8.1 2.0 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 CAR29570.1 - 3.4e-06 26.7 9.1 3.4e-06 26.7 6.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2029) PMT_2 PF13231.1 CAR29570.1 - 0.85 9.5 21.8 0.026 14.4 9.9 2.2 2 0 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Mito_carr PF00153.22 CAR29572.1 - 2.5e-55 184.1 4.3 3.6e-19 68.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SPC12 PF06645.8 CAR29574.1 - 2.7e-22 78.3 0.4 3.2e-22 78.1 0.3 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) FGGY_N PF00370.16 CAR29575.1 - 1.1e-25 90.3 0.0 6.8e-16 58.3 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 CAR29575.1 - 3.6e-10 39.7 0.0 2.1e-09 37.3 0.0 2.3 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Biotin_lipoyl PF00364.17 CAR29576.1 - 1.2e-18 66.4 1.2 4.3e-18 64.7 0.8 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 CAR29576.1 - 1.5e-05 24.5 4.2 3.5e-05 23.3 0.1 3.2 3 0 0 3 3 3 1 Biotin-lipoyl like E3_binding PF02817.12 CAR29576.1 - 0.0016 18.0 0.0 0.0039 16.8 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain HlyD_3 PF13437.1 CAR29576.1 - 0.086 13.1 0.8 2.9 8.2 0.1 2.9 3 0 0 3 3 3 0 HlyD family secretion protein ATP-sulfurylase PF01747.12 CAR29577.1 - 1.4e-86 289.2 0.0 1.8e-86 288.8 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 CAR29577.1 - 5.8e-49 165.5 0.0 1.1e-48 164.6 0.0 1.5 1 0 0 1 1 1 1 PUA-like domain Gp_dh_C PF02800.15 CAR29578.1 - 4.8e-74 247.0 0.1 7.1e-74 246.4 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CAR29578.1 - 6.3e-58 195.0 0.1 1e-57 194.3 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 CAR29578.1 - 0.005 16.7 0.5 0.018 14.9 0.1 2.2 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Poty_coat PF00767.13 CAR29578.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Potyvirus coat protein Memo PF01875.12 CAR29579.1 - 6.9e-89 297.3 0.0 7.9e-89 297.1 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein EIF_2_alpha PF07541.7 CAR29580.1 - 3.5e-41 139.4 1.1 9.7e-41 138.0 0.1 2.0 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 CAR29580.1 - 3.1e-14 52.7 2.7 3.2e-14 52.7 0.9 1.8 2 0 0 2 2 2 1 S1 RNA binding domain EXOSC1 PF10447.4 CAR29580.1 - 0.052 13.4 0.3 0.15 12.0 0.2 1.8 1 1 0 1 1 1 0 Exosome component EXOSC1/CSL4 Viral_env_E26 PF11050.3 CAR29580.1 - 0.18 10.9 1.8 0.16 11.1 0.2 1.6 2 0 0 2 2 2 0 Virus envelope protein E26 Rap_GAP PF02145.10 CAR29581.1 - 2.8e-42 144.2 0.8 4.7e-42 143.4 0.6 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 CAR29581.1 - 2.9e-12 46.3 0.0 5.8e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Tuberin DUF3384 PF11864.3 CAR29581.1 - 3.6e-08 32.3 1.0 1.1e-07 30.7 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Ric8 PF10165.4 CAR29581.1 - 0.22 10.3 5.0 1.7 7.3 1.0 2.5 3 0 0 3 3 3 0 Guanine nucleotide exchange factor synembryn Neur PF00064.13 CAR29582.1 - 0.064 11.3 0.0 0.09 10.8 0.0 1.1 1 0 0 1 1 1 0 Neuraminidase DUF1214 PF06742.6 CAR29582.1 - 0.07 13.6 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1214) Glyco_hydro_16 PF00722.16 CAR29583.1 - 4.7e-47 159.6 1.4 4.7e-47 159.6 1.0 2.4 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 DUF605 PF04652.11 CAR29583.1 - 1.4 8.2 26.8 1.9 7.8 18.6 1.2 1 0 0 1 1 1 0 Vta1 like RNA_pol_Rpb4 PF03874.11 CAR29584.1 - 1.9e-32 111.7 3.5 2.4e-32 111.3 2.4 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Pex19 PF04614.7 CAR29584.1 - 0.02 14.5 1.8 0.021 14.4 0.5 1.5 1 1 1 2 2 2 0 Pex19 protein family PilN PF05137.8 CAR29584.1 - 0.38 10.6 2.0 2.8 7.8 0.1 2.5 1 1 1 2 2 2 0 Fimbrial assembly protein (PilN) Gemini_C4 PF01492.12 CAR29584.1 - 0.41 10.4 4.2 0.19 11.4 0.8 2.1 2 1 1 3 3 3 0 Geminivirus C4 protein VTC PF09359.5 CAR29585.1 - 7.1e-104 346.7 0.1 1.1e-103 346.2 0.1 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 CAR29585.1 - 3.3e-20 72.9 17.8 3e-10 40.3 2.6 4.3 2 2 2 4 4 4 2 SPX domain DUF202 PF02656.10 CAR29585.1 - 2e-08 34.3 6.7 4.2e-08 33.2 4.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Mad3_BUB1_I PF08311.7 CAR29586.1 - 2e-42 143.9 1.2 2e-42 143.9 0.9 2.6 3 0 0 3 3 3 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.6 CAR29586.1 - 1.5e-26 92.0 0.2 4.8e-26 90.4 0.1 1.9 2 0 0 2 2 2 1 Mad3/BUB1 homology region 2 Pkinase PF00069.20 CAR29586.1 - 6.2e-19 68.1 0.0 1.1e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR29586.1 - 0.0036 16.4 0.0 0.0061 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Cpn60_TCP1 PF00118.19 CAR29587.1 - 4.9e-151 503.6 1.4 5.6e-151 503.4 1.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Glyco_hydro_44 PF12891.2 CAR29588.1 - 0.12 11.8 0.1 0.19 11.1 0.1 1.2 1 0 0 1 1 1 0 Glycoside hydrolase family 44 Sad1_UNC PF07738.8 CAR29589.1 - 6.2e-08 32.5 0.1 1.5e-05 24.7 0.0 2.9 2 1 0 2 2 2 1 Sad1 / UNC-like C-terminal Baculo_PEP_C PF04513.7 CAR29589.1 - 0.07 12.9 1.2 0.16 11.7 0.6 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus UPF0118 PF01594.11 CAR29589.1 - 0.37 9.7 0.7 0.9 8.4 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function DUF20 Bot1p PF12298.3 CAR29590.1 - 3.9e-63 212.4 0.3 5.5e-63 211.9 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein AA_permease PF00324.16 CAR29591.1 - 1.1e-117 393.3 35.5 1.4e-117 393.0 24.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CAR29591.1 - 9.7e-35 119.9 32.9 1.2e-34 119.6 22.8 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1672 PF07901.6 CAR29591.1 - 0.024 13.6 0.1 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1672) Thioredoxin PF00085.15 CAR29592.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin His_Phos_1 PF00300.17 CAR29593.1 - 8.4e-36 123.4 0.0 1.1e-35 123.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) TIM PF00121.13 CAR29594.1 - 9.8e-88 293.3 0.0 1.1e-87 293.1 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Alg14 PF08660.6 CAR29595.1 - 3.9e-52 176.6 0.1 5e-52 176.3 0.1 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like ODR4-like PF14778.1 CAR29596.1 - 0.019 13.6 0.4 0.028 13.1 0.3 1.3 1 1 0 1 1 1 0 Olfactory receptor 4-like SNF2_N PF00176.18 CAR29597.1 - 2.6e-63 213.5 0.0 4.2e-63 212.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HDA2-3 PF11496.3 CAR29597.1 - 3.5e-13 49.0 2.2 3.5e-13 49.0 1.5 2.4 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Helicase_C PF00271.26 CAR29597.1 - 3.2e-12 46.1 0.0 9.2e-12 44.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAR29597.1 - 3.8e-09 36.2 0.0 1.3e-08 34.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 CAR29597.1 - 1.9e-07 31.1 0.2 2.4e-06 27.4 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2439 PF10382.4 CAR29597.1 - 8.7e-05 22.6 1.2 0.00021 21.4 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2439) AAA_12 PF13087.1 CAR29597.1 - 0.067 12.5 1.9 0.12 11.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain Ank PF00023.25 CAR29598.1 - 0.00085 19.0 0.0 0.0084 15.8 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 CAR29598.1 - 0.0026 17.9 0.0 0.0059 16.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 CAR29598.1 - 0.0033 17.7 0.0 0.0074 16.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) zf-C2H2_2 PF12756.2 CAR29598.1 - 0.035 14.2 0.1 0.1 12.7 0.1 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 CAR29598.1 - 0.21 11.5 1.2 7.1 6.6 0.0 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger URO-D PF01208.12 CAR29599.1 - 1.7e-122 408.6 0.0 1.9e-122 408.4 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Peptidase_M28 PF04389.12 CAR29600.1 - 5.4e-29 101.1 0.0 1.1e-28 100.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 CAR29600.1 - 0.00076 19.0 0.0 0.00099 18.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 CAR29600.1 - 0.00081 18.2 0.0 0.0036 16.1 0.0 1.8 1 1 1 2 2 2 1 M42 glutamyl aminopeptidase TPR_11 PF13414.1 CAR29601.1 - 3.4e-16 58.6 5.5 0.0017 17.9 0.1 5.7 5 1 1 6 6 6 4 TPR repeat TPR_1 PF00515.23 CAR29601.1 - 4.4e-11 41.9 1.1 0.046 13.3 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 CAR29601.1 - 1.4e-10 40.2 2.8 0.55 10.2 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 CAR29601.1 - 1.3e-08 34.3 0.8 0.043 14.0 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 CAR29601.1 - 9.1e-06 25.5 4.0 5.2 7.0 0.1 5.5 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 CAR29601.1 - 8.5e-05 22.8 6.3 7.3 7.5 0.0 6.2 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 CAR29601.1 - 0.00015 22.3 3.6 0.97 10.1 0.0 5.0 6 0 0 6 6 5 1 Tetratricopeptide repeat ChAPs PF09295.5 CAR29601.1 - 0.00016 20.5 0.9 0.019 13.7 0.0 3.0 3 1 1 4 4 4 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.1 CAR29601.1 - 0.00022 21.4 2.4 2.4 8.5 0.0 5.4 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 CAR29601.1 - 0.0012 18.6 2.6 2.6 7.9 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 CAR29601.1 - 0.0055 16.4 6.1 0.12 12.2 0.0 4.6 6 0 0 6 6 5 1 Tetratricopeptide repeat Syntaxin-6_N PF09177.6 CAR29601.1 - 0.082 13.3 0.0 0.96 9.8 0.0 2.5 2 0 0 2 2 2 0 Syntaxin 6, N-terminal TPR_7 PF13176.1 CAR29601.1 - 0.086 12.6 5.5 0.16 11.8 0.1 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF3439 PF11921.3 CAR29601.1 - 0.15 11.8 3.1 0.34 10.6 2.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Fungal_trans_2 PF11951.3 CAR29602.1 - 6.5e-07 28.2 0.5 1.2e-05 24.0 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR29602.1 - 1.6e-05 24.6 12.8 3.4e-05 23.6 8.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dfp1_Him1_M PF08630.5 CAR29603.1 - 1.5e-45 153.9 0.5 6.6e-45 151.9 0.0 2.3 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.7 CAR29603.1 - 2.7e-22 78.1 1.1 5.4e-22 77.2 0.7 1.5 1 0 0 1 1 1 1 DBF zinc finger AAA_14 PF13173.1 CAR29603.1 - 0.018 14.9 0.1 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF3984 PF13136.1 CAR29604.1 - 0.051 12.7 0.1 0.06 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) UQ_con PF00179.21 CAR29605.1 - 3.9e-44 149.4 0.0 5.4e-44 149.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CAR29605.1 - 0.013 15.2 0.0 0.051 13.3 0.0 1.9 1 1 0 1 1 1 0 Prokaryotic E2 family B Amidase PF01425.16 CAR29606.1 - 1.1e-74 251.8 0.0 1.4e-74 251.5 0.0 1.1 1 0 0 1 1 1 1 Amidase Recep_L_domain PF01030.19 CAR29607.1 - 0.00024 21.0 12.6 0.43 10.5 1.1 4.6 1 1 3 4 4 4 3 Receptor L domain LRR_4 PF12799.2 CAR29607.1 - 0.0013 18.3 0.5 0.0013 18.3 0.3 4.2 4 1 0 4 4 4 1 Leucine Rich repeats (2 copies) PCI PF01399.22 CAR29608.1 - 4.2e-11 43.0 1.2 5.1e-10 39.5 0.1 3.1 2 0 0 2 2 2 1 PCI domain AAA PF00004.24 CAR29609.1 - 4.3e-53 179.0 0.0 1e-38 132.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.12 CAR29609.1 - 4.4e-12 45.4 0.5 2.7e-11 42.9 0.1 2.3 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 CDC48_N PF02359.13 CAR29609.1 - 3.1e-11 43.0 0.0 1.5e-10 40.8 0.0 2.1 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain AAA_19 PF13245.1 CAR29609.1 - 1.4e-09 37.5 0.1 0.0022 17.7 0.1 2.6 2 0 0 2 2 2 2 Part of AAA domain AAA_22 PF13401.1 CAR29609.1 - 1.7e-09 37.8 0.8 0.00033 20.7 0.2 3.5 2 2 0 2 2 2 2 AAA domain TIP49 PF06068.8 CAR29609.1 - 8.3e-09 34.6 0.1 0.0019 17.0 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_16 PF13191.1 CAR29609.1 - 2.3e-08 34.2 0.0 0.0043 17.0 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 CAR29609.1 - 2.7e-08 34.6 0.2 0.004 17.9 0.1 2.7 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CAR29609.1 - 1.1e-07 31.6 0.0 0.0013 18.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CAR29609.1 - 1.1e-07 31.8 0.0 0.0022 17.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 CAR29609.1 - 1.9e-07 30.4 0.0 0.0022 17.1 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 CAR29609.1 - 4.9e-07 29.0 0.1 0.044 12.8 0.0 2.8 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 CAR29609.1 - 7e-07 29.6 0.1 0.0032 17.7 0.0 2.7 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 CAR29609.1 - 2.2e-06 27.1 0.1 0.063 12.6 0.0 2.6 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 CAR29609.1 - 2.7e-06 27.2 0.0 0.034 14.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 CAR29609.1 - 1.8e-05 24.7 0.0 0.00084 19.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 CAR29609.1 - 2.7e-05 24.2 0.0 0.072 13.2 0.0 2.9 2 0 0 2 2 2 1 RNA helicase Zeta_toxin PF06414.7 CAR29609.1 - 5.8e-05 22.2 0.0 0.059 12.4 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin ABC_tran PF00005.22 CAR29609.1 - 8.7e-05 22.8 0.3 0.024 14.9 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA_11 PF13086.1 CAR29609.1 - 0.00014 21.4 0.0 0.29 10.6 0.0 2.4 2 1 0 2 2 2 2 AAA domain NACHT PF05729.7 CAR29609.1 - 0.00034 20.3 2.4 0.7 9.5 0.0 3.9 4 1 1 5 5 4 1 NACHT domain PhoH PF02562.11 CAR29609.1 - 0.00036 19.8 0.0 0.34 10.1 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein Sigma54_activat PF00158.21 CAR29609.1 - 0.00049 19.6 0.0 0.97 8.8 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain NB-ARC PF00931.17 CAR29609.1 - 0.00066 18.6 0.0 1.1 8.0 0.0 2.6 3 0 0 3 3 2 2 NB-ARC domain AAA_3 PF07726.6 CAR29609.1 - 0.0011 18.5 0.0 0.13 11.9 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 CAR29609.1 - 0.0014 18.1 0.0 0.041 13.3 0.0 2.2 2 0 0 2 2 2 1 AAA-like domain AAA_24 PF13479.1 CAR29609.1 - 0.0015 18.1 2.8 0.18 11.3 0.3 3.0 2 1 0 2 2 2 1 AAA domain UPF0079 PF02367.12 CAR29609.1 - 0.0015 18.1 0.1 1.3 8.6 0.0 2.8 3 0 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 DUF2075 PF09848.4 CAR29609.1 - 0.0017 17.3 0.0 0.1 11.5 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.1 CAR29609.1 - 0.0019 18.2 0.3 4.5 7.3 0.1 3.4 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.1 CAR29609.1 - 0.0019 17.6 5.3 1 8.7 0.1 3.8 2 2 1 4 4 4 2 AAA domain KaiC PF06745.8 CAR29609.1 - 0.0031 16.6 0.6 0.27 10.3 0.0 3.0 3 0 0 3 3 3 1 KaiC AAA_28 PF13521.1 CAR29609.1 - 0.0047 16.9 0.0 3.2 7.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain Bac_DnaA PF00308.13 CAR29609.1 - 0.0053 16.4 0.0 5.3 6.6 0.0 3.2 3 0 0 3 3 3 0 Bacterial dnaA protein AAA_30 PF13604.1 CAR29609.1 - 0.0073 15.9 0.0 1.9 8.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 CAR29609.1 - 0.0078 16.0 0.0 3.4 7.4 0.0 2.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 CAR29609.1 - 0.0083 15.8 0.6 17 5.0 0.0 3.2 2 1 1 3 3 3 0 Archaeal ATPase T2SE PF00437.15 CAR29609.1 - 0.026 13.4 0.0 4.5 6.1 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein DAP3 PF10236.4 CAR29609.1 - 0.029 13.3 0.4 11 4.8 0.0 3.1 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.1 CAR29609.1 - 0.044 13.3 0.2 1.5 8.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.12 CAR29609.1 - 0.052 12.4 0.0 1.8 7.3 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 KTI12 PF08433.5 CAR29609.1 - 0.065 12.4 0.1 2.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_23 PF13476.1 CAR29609.1 - 0.085 13.1 3.0 9.3 6.5 1.4 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 CAR29609.1 - 0.12 11.8 1.4 7.7 5.9 0.0 3.3 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain PRKCSH PF07915.8 CAR29611.1 - 9.7e-09 35.9 0.6 9.7e-09 35.9 0.4 3.3 3 1 0 3 3 3 1 Glucosidase II beta subunit-like protein Prog_receptor PF02161.10 CAR29611.1 - 6.3 5.5 7.0 0.17 10.6 0.1 1.7 2 0 0 2 2 2 0 Progesterone receptor Bromodomain PF00439.20 CAR29612.1 - 5.2e-17 61.5 3.3 6.1e-17 61.3 0.4 2.6 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.8 CAR29612.1 - 4.5e-05 23.0 0.0 0.0024 17.5 0.0 2.5 1 1 1 2 2 2 1 Bromodomain associated UQ_con PF00179.21 CAR29613.1 - 3.4e-51 172.3 0.0 3.8e-51 172.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CAR29613.1 - 6e-05 22.8 0.0 7.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CAR29613.1 - 0.00035 20.4 0.0 0.0004 20.2 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 CAR29613.1 - 0.015 14.9 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain CBF PF03914.12 CAR29614.1 - 2.9e-43 147.1 0.9 2.9e-43 147.1 0.6 2.9 3 0 0 3 3 3 1 CBF/Mak21 family TEA PF01285.13 CAR29615.1 - 6.4e-30 104.6 0.0 6.4e-30 104.6 0.0 1.9 2 1 0 2 2 2 1 TEA/ATTS domain family FTHFS PF01268.14 CAR29616.1 - 2.8e-253 840.9 0.4 3.6e-253 840.6 0.3 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 CAR29616.1 - 2.2e-68 228.4 0.1 2.2e-68 228.4 0.1 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 CAR29616.1 - 7.3e-35 119.5 0.2 1.8e-34 118.2 0.2 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AdoHcyase_NAD PF00670.16 CAR29616.1 - 0.034 13.9 0.3 1.6 8.5 0.2 2.6 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Ribosomal_L19e PF01280.15 CAR29617.1 - 3.1e-58 195.7 11.0 3.1e-58 195.7 7.6 1.6 1 1 1 2 2 2 1 Ribosomal protein L19e DUF2423 PF10338.4 CAR29618.1 - 1.9e-14 53.3 8.9 1.9e-14 53.3 6.2 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2423) YlqD PF11068.3 CAR29618.1 - 0.036 14.1 3.4 0.048 13.6 2.4 1.1 1 0 0 1 1 1 0 YlqD protein ATP-synt_E PF05680.7 CAR29618.1 - 6.4 6.7 10.8 11 6.1 7.5 1.6 1 1 0 1 1 1 0 ATP synthase E chain U79_P34 PF03064.11 CAR29618.1 - 9.4 5.6 11.2 11 5.5 7.8 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Prim_Zn_Ribbon PF08273.7 CAR29620.1 - 0.0022 18.0 1.3 0.041 13.9 0.2 2.1 2 0 0 2 2 2 1 Zinc-binding domain of primase-helicase Zn_Tnp_IS1595 PF12760.2 CAR29620.1 - 0.049 13.4 5.5 0.66 9.8 3.8 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Cys_rich_CPCC PF14206.1 CAR29620.1 - 0.073 12.6 1.1 0.21 11.1 0.1 2.0 2 0 0 2 2 2 0 Cysteine-rich CPCC DRP PF06044.7 CAR29620.1 - 0.23 10.4 1.2 0.32 9.9 0.3 1.6 2 0 0 2 2 2 0 Dam-replacing family zf-Sec23_Sec24 PF04810.10 CAR29620.1 - 0.25 10.9 0.3 0.25 10.9 0.2 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-ribbon_3 PF13248.1 CAR29620.1 - 0.43 9.8 3.0 1.1 8.6 0.3 2.4 3 0 0 3 3 3 0 zinc-ribbon domain zf-Mss51 PF13824.1 CAR29620.1 - 1.6 8.6 5.6 2.8 7.8 2.5 2.3 1 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-LITAF-like PF10601.4 CAR29620.1 - 4 7.3 7.3 0.18 11.7 0.6 2.0 2 1 0 2 2 2 0 LITAF-like zinc ribbon domain Mito_carr PF00153.22 CAR29621.1 - 3.6e-70 231.7 4.9 4.5e-25 87.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein KH_1 PF00013.24 CAR29623.1 - 3.8e-27 93.7 7.3 2e-10 40.1 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 CAR29623.1 - 8.1e-17 60.4 10.7 1.1e-08 34.5 0.1 3.7 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 CAR29623.1 - 8.5e-09 34.8 8.0 0.00071 19.0 0.0 3.7 4 0 0 4 4 4 3 KH domain KH_4 PF13083.1 CAR29623.1 - 2.4e-05 23.8 1.5 0.63 9.7 0.0 3.7 4 0 0 4 4 4 2 KH domain KH_5 PF13184.1 CAR29623.1 - 0.0097 15.6 6.1 0.79 9.5 0.2 3.4 3 0 0 3 3 3 2 NusA-like KH domain GTP_cyclohydro2 PF00925.15 CAR29624.1 - 1.9e-55 186.6 0.0 1.5e-50 170.7 0.0 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II CLASP_N PF12348.3 CAR29626.1 - 2.7e-66 223.1 10.9 2.7e-66 223.1 4.0 3.1 3 0 0 3 3 3 1 CLASP N terminal Pol_alpha_B_N PF08418.5 CAR29627.1 - 6.4e-61 206.0 1.5 9.6e-61 205.5 1.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 CAR29627.1 - 3.7e-44 150.5 0.5 5.3e-44 149.9 0.4 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Anoctamin PF04547.7 CAR29628.1 - 2.5e-40 138.4 12.6 2.5e-38 131.9 8.7 2.3 1 1 0 1 1 1 1 Calcium-activated chloride channel EamA PF00892.15 CAR29630.1 - 1.6e-24 86.3 27.9 1.1e-13 51.2 6.2 2.5 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 CAR29630.1 - 1.8e-08 34.5 6.2 1.8e-08 34.5 4.3 3.4 2 1 0 2 2 2 1 Multidrug resistance efflux transporter DUF914 PF06027.7 CAR29630.1 - 3.9e-05 22.6 5.1 6.3e-05 21.9 3.5 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 CAR29630.1 - 0.0081 15.1 14.1 0.011 14.6 7.5 2.2 1 1 1 2 2 2 2 UAA transporter family TPT PF03151.11 CAR29630.1 - 1.1 8.8 22.0 0.024 14.2 4.1 2.8 2 1 0 2 2 2 0 Triose-phosphate Transporter family Mg_trans_NIPA PF05653.9 CAR29630.1 - 1.4 7.8 9.8 0.073 12.0 2.0 2.2 3 1 0 3 3 3 0 Magnesium transporter NIPA TAF8_C PF10406.4 CAR29631.1 - 3.1 7.9 7.3 2.2 8.4 1.2 2.6 1 1 1 2 2 2 0 Transcription factor TFIID complex subunit 8 C-term Peptidase_U57 PF05582.7 CAR29631.1 - 4.6 6.1 6.1 1.5 7.6 2.6 1.4 1 1 0 1 1 1 0 YabG peptidase U57 CorA PF01544.13 CAR29631.1 - 8.5 5.3 7.1 11 4.9 4.9 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein PDR_assoc PF08370.6 CAR29632.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 Plant PDR ABC transporter associated COX7a PF02238.10 CAR29633.1 - 0.14 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIa zf-C3HC4_2 PF13923.1 CAR29634.1 - 1e-08 35.0 9.3 1e-08 35.0 6.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CAR29634.1 - 1e-08 34.6 9.0 1e-08 34.6 6.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CAR29634.1 - 1.5e-08 34.4 10.4 1.5e-08 34.4 7.2 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 CAR29634.1 - 2.8e-08 33.2 13.8 4.8e-07 29.3 3.8 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CAR29634.1 - 1.5e-07 31.1 9.3 1.5e-07 31.1 6.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 CAR29634.1 - 8.2e-07 28.6 3.2 1.8e-06 27.5 2.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 CAR29634.1 - 4.3e-06 26.3 7.7 4.3e-06 26.3 5.3 2.5 2 1 0 2 2 2 1 zinc-RING finger domain zf-UDP PF14569.1 CAR29634.1 - 0.00011 21.8 10.6 0.0048 16.6 0.6 3.3 2 1 0 2 2 2 2 Zinc-binding RING-finger DZR PF12773.2 CAR29634.1 - 0.00077 19.2 9.9 0.13 12.1 0.2 2.5 2 0 0 2 2 2 2 Double zinc ribbon zf-rbx1 PF12678.2 CAR29634.1 - 0.0012 18.9 3.9 0.0012 18.9 2.7 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CAR29634.1 - 0.0029 17.4 2.6 0.0029 17.4 1.8 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_2 PF13240.1 CAR29634.1 - 0.0068 15.8 8.1 0.017 14.5 0.5 3.2 3 0 0 3 3 3 1 zinc-ribbon domain zf-MIZ PF02891.15 CAR29634.1 - 0.016 14.7 8.0 0.016 14.7 5.5 2.2 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-RING_6 PF14835.1 CAR29634.1 - 0.017 14.9 9.6 0.048 13.4 2.5 2.3 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 CAR29634.1 - 0.029 13.9 14.9 0.64 9.6 5.4 2.9 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C4_Topoisom PF01396.14 CAR29634.1 - 0.099 12.1 1.2 1.6 8.2 0.1 2.4 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger BTV_NS2 PF04514.7 CAR29634.1 - 0.12 11.2 0.1 0.12 11.2 0.0 2.9 1 1 1 2 2 1 0 Bluetongue virus non-structural protein NS2 Zn_ribbon_recom PF13408.1 CAR29634.1 - 2.7 8.3 6.7 12 6.2 0.1 3.2 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain FANCL_C PF11793.3 CAR29634.1 - 5.4 7.0 9.5 61 3.6 0.0 3.0 2 1 0 2 2 2 0 FANCL C-terminal domain RNHCP PF12647.2 CAR29634.1 - 7.3 6.4 9.0 26 4.7 0.1 2.9 2 1 0 2 2 2 0 RNHCP domain F-box-like PF12937.2 CAR29636.1 - 0.072 12.8 1.2 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 F-box-like DUF2428 PF10350.4 CAR29637.1 - 1.6e-57 194.4 0.6 1.6e-57 194.4 0.4 2.5 3 0 0 3 3 3 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 CAR29637.1 - 6.7e-11 41.3 0.8 0.0079 16.1 0.0 5.4 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 CAR29637.1 - 3.9e-07 30.2 0.0 0.02 15.1 0.0 3.9 3 0 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 CAR29637.1 - 2e-05 24.9 0.5 0.00072 19.9 0.0 3.4 3 0 0 3 3 3 1 HEAT-like repeat eIF-1a PF01176.14 CAR29638.1 - 4.4e-27 93.2 0.3 5.9e-27 92.8 0.2 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Myb_DNA-bind_6 PF13921.1 CAR29638.1 - 0.098 12.7 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Glyco_transf_20 PF00982.16 CAR29639.1 - 3.5e-166 553.3 0.3 4.9e-166 552.8 0.2 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 CAR29639.1 - 2.5e-38 131.3 0.0 5.8e-38 130.1 0.0 1.6 2 0 0 2 2 2 1 Trehalose-phosphatase TatD_DNase PF01026.16 CAR29640.1 - 1.8e-38 132.2 0.1 2.2e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase SAP30_Sin3_bdg PF13867.1 CAR29641.1 - 5.7e-14 51.7 0.2 4.8e-11 42.3 0.0 2.3 2 0 0 2 2 2 2 Sin3 binding region of histone deacetylase complex subunit SAP30 CUE PF02845.11 CAR29642.1 - 1.4e-10 40.3 0.0 2.3e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 CUE domain Di19_C PF14571.1 CAR29642.1 - 1.2 9.4 4.1 0.41 10.9 0.2 2.2 2 2 0 2 2 2 0 Stress-induced protein Di19, C-terminal WD40 PF00400.27 CAR29643.1 - 1e-29 101.2 0.8 4.9e-06 26.2 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 CAR29643.1 - 9.4e-05 22.1 0.2 0.014 15.0 0.0 3.2 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 CAR29643.1 - 0.0036 16.1 0.1 0.47 9.1 0.0 2.3 1 1 0 2 2 2 2 Coatomer WD associated region DUF2410 PF10307.4 CAR29644.1 - 3.3e-47 160.4 0.0 5.1e-47 159.8 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) DUF221 PF02714.10 CAR29645.1 - 3.6e-101 338.2 19.9 3.6e-101 338.2 13.8 2.0 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CAR29645.1 - 2e-40 137.9 4.9 2e-40 137.9 3.4 2.4 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 CAR29645.1 - 1.7e-25 88.7 0.0 4.6e-25 87.3 0.0 1.8 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 CAR29645.1 - 2.4e-15 56.8 4.2 5.4e-15 55.6 2.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Pyrophosphatase PF00719.14 CAR29646.1 - 5.2e-52 175.4 0.0 7e-52 174.9 0.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Nup188 PF10487.4 CAR29647.1 - 4.2e-223 743.1 26.2 6.2e-223 742.5 18.1 1.2 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 RRM_1 PF00076.17 CAR29648.1 - 1.2e-37 127.3 0.4 2.6e-13 49.3 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR29648.1 - 1.1e-30 105.4 0.1 9.8e-10 38.2 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR29648.1 - 7.4e-11 41.7 0.4 6.4e-07 29.1 0.0 3.6 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lsm_interact PF05391.6 CAR29648.1 - 8.6e-08 31.2 0.2 1.8e-07 30.2 0.1 1.6 1 0 0 1 1 1 1 Lsm interaction motif Nup35_RRM_2 PF14605.1 CAR29648.1 - 0.0036 17.0 0.0 3 7.6 0.0 3.3 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif DbpA PF03880.10 CAR29648.1 - 0.0079 15.8 1.5 5.3 6.7 0.0 3.1 3 0 0 3 3 3 2 DbpA RNA binding domain ACT_3 PF10000.4 CAR29648.1 - 0.14 11.9 0.1 1.3 8.7 0.0 2.4 3 0 0 3 3 3 0 ACT domain G-patch PF01585.18 CAR29649.1 - 0.00099 18.8 2.3 0.00099 18.8 1.6 2.6 2 0 0 2 2 2 1 G-patch domain SprA-related PF12118.3 CAR29649.1 - 0.21 10.9 15.6 0.23 10.7 10.8 1.1 1 0 0 1 1 1 0 SprA-related family RNase_H2-Ydr279 PF09468.5 CAR29649.1 - 0.26 10.4 19.9 0.34 10.0 13.8 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) RR_TM4-6 PF06459.7 CAR29649.1 - 0.26 11.1 19.5 0.3 10.9 13.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1510 PF07423.6 CAR29649.1 - 0.85 8.9 26.1 1.1 8.5 18.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) GAGA_bind PF06217.7 CAR29649.1 - 2.7 7.8 18.5 3.3 7.5 12.8 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Zip PF02535.17 CAR29649.1 - 4.3 6.2 7.0 4.9 6.0 4.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter PXA PF02194.10 CAR29650.1 - 1.9e-38 131.8 1.2 1.9e-38 131.8 0.8 2.7 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 CAR29650.1 - 7e-26 90.5 0.5 2.5e-25 88.7 0.1 2.3 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 CAR29650.1 - 4.7e-15 55.3 4.1 4.7e-15 55.3 2.8 2.7 3 0 0 3 3 3 1 PX domain RRN9 PF10680.4 CAR29651.1 - 9e-18 63.7 0.7 2.2e-17 62.5 0.5 1.7 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor SRP19 PF01922.12 CAR29652.1 - 6.1e-28 97.2 0.0 1.2e-27 96.3 0.0 1.5 1 0 0 1 1 1 1 SRP19 protein Pribosyltran PF00156.22 CAR29653.1 - 7.5e-18 64.4 0.3 1.7e-17 63.3 0.1 1.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain zf-C3HC PF07967.8 CAR29654.1 - 1.4e-09 37.7 14.0 1.1e-06 28.4 3.9 2.7 1 1 2 3 3 3 2 C3HC zinc finger-like zf-CSL PF05207.8 CAR29654.1 - 0.44 10.1 5.5 1.7 8.1 0.3 2.5 2 0 0 2 2 2 0 CSL zinc finger Rsm1 PF08600.5 CAR29654.1 - 2.6 7.9 10.4 0.4 10.5 1.2 3.3 3 1 0 3 3 3 0 Rsm1-like Cyt-b5 PF00173.23 CAR29655.1 - 1.2e-23 82.6 1.0 7.2e-23 80.1 0.1 2.4 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 CAR29655.1 - 1.2e-11 44.9 14.6 1.2e-11 44.9 10.1 2.1 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.8 CAR29655.1 - 0.1 12.6 0.3 0.2 11.6 0.2 1.5 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region DUF1892 PF08987.5 CAR29656.1 - 2.1e-44 150.1 2.5 2.5e-44 149.9 1.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1892) Zds_C PF08632.5 CAR29657.1 - 4.9e-33 112.2 1.5 8.5e-33 111.5 1.0 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Abi PF02517.11 CAR29658.1 - 1.2e-14 54.1 5.1 1.2e-14 54.1 3.5 2.2 2 0 0 2 2 2 1 CAAX protease self-immunity Ubie_methyltran PF01209.13 CAR29659.1 - 6.9e-99 329.6 0.2 8.7e-99 329.3 0.2 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 CAR29659.1 - 1e-12 47.9 0.1 1.5e-12 47.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CAR29659.1 - 2.4e-09 37.5 0.0 4.1e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAR29659.1 - 3.5e-09 37.0 0.1 6.4e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAR29659.1 - 1.1e-07 32.1 0.0 1.8e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAR29659.1 - 2.9e-06 27.1 0.0 4.6e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR29659.1 - 3.4e-06 27.5 0.0 5.7e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CAR29659.1 - 0.00081 19.4 0.0 0.0029 17.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 CAR29659.1 - 0.025 13.9 0.0 0.075 12.4 0.0 1.7 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_5 PF01795.14 CAR29659.1 - 0.11 11.7 0.0 0.33 10.1 0.0 1.7 2 0 0 2 2 2 0 MraW methylase family Methyltransf_8 PF05148.10 CAR29659.1 - 0.13 11.9 0.0 0.92 9.0 0.0 2.0 1 1 1 2 2 2 0 Hypothetical methyltransferase Bul1_N PF04425.7 CAR29660.1 - 3e-159 530.2 1.8 5.7e-159 529.3 0.7 1.8 2 0 0 2 2 2 1 Bul1 N terminus Bul1_C PF04426.7 CAR29660.1 - 1.6e-105 352.2 5.6 3.1e-105 351.2 3.8 1.5 1 0 0 1 1 1 1 Bul1 C terminus Lzipper-MIP1 PF14389.1 CAR29660.1 - 0.011 15.7 0.6 0.034 14.2 0.4 1.7 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 CTK3_C PF12350.3 CAR29661.1 - 4e-24 84.4 0.6 9.3e-24 83.2 0.2 1.8 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus CTK3 PF12243.3 CAR29661.1 - 1.5e-07 31.1 0.5 2.6e-07 30.3 0.4 1.4 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 DUF3987 PF13148.1 CAR29662.1 - 0.014 13.9 4.5 0.019 13.5 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) FYDLN_acid PF09538.5 CAR29662.1 - 0.23 12.0 3.8 0.45 11.1 2.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) TPPII_N PF12583.3 CAR29662.1 - 1.3 9.1 18.9 2.8 8.0 13.1 1.5 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal Med3 PF11593.3 CAR29662.1 - 2.1 7.5 15.6 3.1 6.9 10.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal ubiquitin PF00240.18 CAR29663.1 - 1.5e-21 75.5 0.3 2.3e-21 74.9 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CAR29663.1 - 7.1e-11 41.6 0.1 1.1e-10 41.0 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.26 CAR29663.1 - 1.9e-07 30.6 1.0 3.3e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain Ubiquitin_2 PF14560.1 CAR29663.1 - 1.5e-06 28.3 0.2 3e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 CAR29663.1 - 0.00039 20.2 0.0 0.00088 19.1 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CAR29663.1 - 0.012 15.7 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain UN_NPL4 PF11543.3 CAR29663.1 - 0.12 12.6 0.2 0.19 12.0 0.2 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 TAF8_C PF10406.4 CAR29664.1 - 8.8e-20 70.5 1.3 8.8e-20 70.5 0.9 3.3 3 0 0 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term NIF PF03031.13 CAR29665.1 - 4.7e-24 84.8 0.3 5.8e-23 81.3 0.0 2.4 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.21 CAR29665.1 - 3e-10 40.1 0.0 8.7e-10 38.6 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CAR29665.1 - 8.1e-06 25.6 0.0 2e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain PGM_PMM_I PF02878.11 CAR29666.1 - 1.5e-38 131.3 0.0 3e-38 130.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 CAR29666.1 - 4e-21 75.2 0.0 1.2e-20 73.8 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 CAR29666.1 - 2.9e-14 53.0 0.0 6.1e-13 48.8 0.0 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 CAR29666.1 - 9.2e-06 25.5 0.0 2.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain 3-HAO PF06052.7 CAR29666.1 - 0.056 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase S-methyl_trans PF02574.11 CAR29667.1 - 2.1e-70 237.4 0.0 2.3e-70 237.2 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Kelch_1 PF01344.20 CAR29667.1 - 0.017 14.6 0.1 0.29 10.7 0.0 2.5 2 0 0 2 2 2 0 Kelch motif Anp1 PF03452.9 CAR29668.1 - 3.2e-122 406.8 0.0 4.3e-122 406.4 0.0 1.2 1 0 0 1 1 1 1 Anp1 Nab6_mRNP_bdg PF10567.4 CAR29669.1 - 5.4e-84 281.8 4.8 5.4e-84 281.8 3.4 3.1 4 0 0 4 4 4 1 RNA-recognition motif RRM PF10378.4 CAR29669.1 - 4.5e-15 54.9 4.9 4.5e-15 54.9 3.4 2.9 3 0 0 3 3 3 1 Putative RRM domain RRM_6 PF14259.1 CAR29669.1 - 3.8e-13 49.2 0.7 1.9e-06 27.7 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR29669.1 - 2.6e-10 39.9 0.4 0.00014 21.6 0.0 3.8 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAR29669.1 - 2.1e-07 30.4 0.8 0.0069 15.9 0.0 4.2 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fungal_trans PF04082.13 CAR29670.1 - 7.3e-36 123.3 0.2 1.4e-35 122.4 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR29670.1 - 1.5e-10 40.7 12.8 2.5e-10 40.1 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PIG-L PF02585.12 CAR29671.1 - 8.9e-21 74.7 0.0 1.2e-20 74.2 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase ATP13 PF12921.2 CAR29672.1 - 1.7e-35 121.0 0.1 7e-35 119.1 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial ATPase expression Init_tRNA_PT PF04179.7 CAR29673.1 - 9e-151 502.7 0.1 1e-150 502.5 0.1 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Ribonuc_red_sm PF00268.16 CAR29674.1 - 1.3e-119 398.3 1.7 1.8e-119 397.9 1.2 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain STN1_2 PF09170.5 CAR29674.1 - 0.027 14.2 0.7 0.051 13.3 0.5 1.4 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 IncA PF04156.9 CAR29674.1 - 1.6 8.3 4.4 2.6 7.5 3.0 1.3 1 0 0 1 1 1 0 IncA protein U3_snoRNA_assoc PF08297.6 CAR29675.1 - 1.8e-12 47.3 6.8 1.8e-12 47.3 4.7 2.2 2 0 0 2 2 2 1 U3 snoRNA associated MCPVI PF02993.9 CAR29675.1 - 0.3 11.1 9.8 0.24 11.5 6.0 1.3 1 1 0 1 1 1 0 Minor capsid protein VI Zip PF02535.17 CAR29676.1 - 1.1e-21 77.1 16.1 1.4e-14 53.8 3.2 2.1 1 1 1 2 2 2 2 ZIP Zinc transporter DUF95 PF01944.12 CAR29676.1 - 1.7 8.2 8.7 1.3 8.6 0.5 3.0 3 0 0 3 3 3 0 Integral membrane protein DUF95 F-box-like PF12937.2 CAR29677.1 - 1.1e-07 31.4 0.2 2.6e-07 30.2 0.1 1.7 1 0 0 1 1 1 1 F-box-like TPR_11 PF13414.1 CAR29677.1 - 1.5e-07 30.9 1.4 5.4e-05 22.7 0.2 3.1 1 1 1 2 2 2 2 TPR repeat TPR_12 PF13424.1 CAR29677.1 - 6e-07 29.3 4.0 0.0046 16.8 0.1 3.4 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 CAR29677.1 - 8.6e-05 22.0 2.3 0.29 11.0 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CAR29677.1 - 0.00054 19.6 5.1 0.036 13.9 0.6 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 CAR29677.1 - 0.00073 19.0 4.1 0.042 13.4 0.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CAR29677.1 - 0.0011 19.4 0.4 1.2 9.9 0.1 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CAR29677.1 - 0.0013 18.6 3.0 0.11 12.3 0.1 2.6 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.1 CAR29677.1 - 0.0014 19.2 3.9 0.32 11.7 0.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat F-box PF00646.28 CAR29677.1 - 0.0037 16.8 1.4 0.0061 16.1 0.1 2.1 2 0 0 2 2 1 1 F-box domain Apc3 PF12895.2 CAR29677.1 - 0.015 15.4 0.9 6.7 6.9 0.1 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 CAR29677.1 - 0.07 13.4 0.1 8.5 6.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 CAR29677.1 - 0.29 11.1 1.9 1.1 9.2 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat LRR_4 PF12799.2 CAR29677.1 - 0.31 10.6 3.6 13 5.5 0.1 3.6 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) TPR_6 PF13174.1 CAR29677.1 - 1.7 9.2 4.3 3 8.4 0.1 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF3336 PF11815.3 CAR29678.1 - 2.2e-38 131.0 5.8 3.8e-38 130.2 4.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 CAR29678.1 - 3.5e-29 102.1 0.0 7.1e-29 101.1 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase Chaperone_III PF07824.7 CAR29678.1 - 0.076 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Type III secretion chaperone domain LIM PF00412.17 CAR29679.1 - 9.4e-16 57.6 20.7 1.1e-08 34.9 5.2 2.4 2 0 0 2 2 2 2 LIM domain Whi5 PF08528.6 CAR29680.1 - 2e-09 36.8 0.1 3.8e-09 35.9 0.1 1.5 1 0 0 1 1 1 1 Whi5 like MarB PF13999.1 CAR29680.1 - 0.0023 17.4 0.5 0.0074 15.8 0.4 1.9 1 0 0 1 1 1 1 MarB protein Abhydrolase_6 PF12697.2 CAR29681.1 - 4.5e-22 79.0 0.0 6e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CAR29681.1 - 0.00061 19.0 0.0 0.00097 18.4 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CAR29681.1 - 0.0014 18.3 0.0 0.0024 17.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 CAR29681.1 - 0.0016 17.9 0.0 0.0026 17.2 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.15 CAR29681.1 - 0.0083 15.7 0.0 0.033 13.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold SRP40_C PF05022.7 CAR29682.1 - 1.1e-27 96.3 4.1 1.1e-27 96.3 2.8 2.6 2 0 0 2 2 2 1 SRP40, C-terminal domain Helicase_C_3 PF13625.1 CAR29683.1 - 9.3e-25 86.8 0.1 3.1e-24 85.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAR29683.1 - 8.8e-14 51.7 0.1 2.3e-13 50.3 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CAR29683.1 - 4.7e-12 45.3 0.1 8.4e-12 44.4 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CAR29683.1 - 6.5e-10 38.7 1.2 1.3e-09 37.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAR29683.1 - 4.2e-07 29.6 0.0 1e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.1 CAR29683.1 - 0.05 12.3 0.0 0.094 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 Med3 PF11593.3 CAR29683.1 - 0.5 9.5 10.3 1.9 7.6 4.7 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Ndc80_HEC PF03801.8 CAR29684.1 - 8.4e-55 184.5 0.7 2e-54 183.3 0.5 1.6 1 0 0 1 1 1 1 HEC/Ndc80p family IncA PF04156.9 CAR29684.1 - 0.0051 16.4 18.7 0.0051 16.4 12.9 3.9 2 1 0 2 2 2 1 IncA protein DUF4200 PF13863.1 CAR29684.1 - 0.0077 16.1 8.4 0.0077 16.1 5.8 5.5 4 1 0 5 5 5 2 Domain of unknown function (DUF4200) FTR1 PF03239.9 CAR29685.1 - 6.8e-95 317.5 7.7 8.1e-95 317.2 5.3 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family FAD_binding_4 PF01565.18 CAR29685.1 - 0.033 13.6 0.0 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain DUF4131 PF13567.1 CAR29685.1 - 5.6 6.3 7.2 10 5.5 1.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) LSM PF01423.17 CAR29686.1 - 5.5e-15 54.6 0.1 6.6e-15 54.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CAR29686.1 - 0.074 12.9 0.0 0.078 12.9 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain PAP2 PF01569.16 CAR29687.1 - 9.7e-08 31.7 7.2 9.7e-08 31.7 5.0 2.8 2 1 0 2 2 2 1 PAP2 superfamily ResB PF05140.9 CAR29687.1 - 2.3 6.6 7.2 2.8 6.3 0.7 2.1 2 0 0 2 2 2 0 ResB-like family Glyco_transf_20 PF00982.16 CAR29689.1 - 6.6e-143 476.6 0.0 8.7e-143 476.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 CAR29689.1 - 3e-84 281.5 0.0 4.5e-84 281.0 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Glycos_transf_1 PF00534.15 CAR29689.1 - 0.005 16.2 0.0 0.016 14.6 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Cohesin_load PF10345.4 CAR29690.1 - 5.6e-102 341.9 25.1 6.8e-102 341.6 17.4 1.0 1 0 0 1 1 1 1 Cohesin loading factor TBP PF00352.16 CAR29691.1 - 6.8e-70 230.4 0.1 4e-35 119.0 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 CAR29691.1 - 0.00013 21.8 0.2 0.61 10.1 0.0 2.6 2 1 1 3 3 3 2 Domain of unknown function (DUF3378) Adenylsucc_synt PF00709.16 CAR29692.1 - 0.071 11.7 1.7 0.11 11.1 1.2 1.2 1 0 0 1 1 1 0 Adenylosuccinate synthetase IncA PF04156.9 CAR29692.1 - 0.47 10.0 18.2 1.1 8.7 6.6 2.3 2 0 0 2 2 2 0 IncA protein Prominin PF05478.6 CAR29692.1 - 6.6 4.1 12.3 15 2.9 8.6 1.6 1 1 0 1 1 1 0 Prominin Metallophos PF00149.23 CAR29693.1 - 2.4e-40 138.0 0.1 3e-40 137.7 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CAR29693.1 - 0.0001 22.2 0.0 0.00015 21.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Rad51 PF08423.6 CAR29694.1 - 0.0004 19.3 0.1 0.0033 16.3 0.0 2.5 4 0 0 4 4 4 1 Rad51 KaiC PF06745.8 CAR29694.1 - 0.0041 16.2 0.0 0.0077 15.3 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 CAR29694.1 - 0.0066 15.8 0.0 0.061 12.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain RecA PF00154.16 CAR29694.1 - 0.038 13.0 0.0 0.068 12.2 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein AA_permease PF00324.16 CAR29696.1 - 9.7e-45 152.7 34.5 9.7e-45 152.7 23.9 1.5 2 0 0 2 2 2 1 Amino acid permease Pox_MCEL PF03291.11 CAR29697.1 - 2.2e-97 325.9 0.0 4.3e-97 324.9 0.0 1.5 1 1 1 2 2 2 1 mRNA capping enzyme Methyltransf_12 PF08242.7 CAR29697.1 - 2.7e-09 37.4 0.0 9e-09 35.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR29697.1 - 4.9e-08 33.5 0.0 9.1e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CAR29697.1 - 1.2e-07 32.0 0.0 2.9e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAR29697.1 - 1.7e-07 31.5 0.0 3.2e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAR29697.1 - 3.4e-07 29.9 0.0 6.2e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAR29697.1 - 5.3e-07 29.4 0.0 9.8e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CAR29697.1 - 0.0005 19.1 0.0 0.001 18.1 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase NNMT_PNMT_TEMT PF01234.12 CAR29697.1 - 0.056 12.4 0.0 0.2 10.5 0.0 1.9 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_26 PF13659.1 CAR29697.1 - 0.066 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 CAR29697.1 - 0.076 12.0 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase TPMT PF05724.6 CAR29697.1 - 0.082 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MetW PF07021.7 CAR29697.1 - 0.11 11.7 0.0 0.38 10.1 0.0 1.7 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW DEAD PF00270.24 CAR29698.1 - 1.1e-42 145.3 0.1 2.7e-42 144.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR29698.1 - 2.4e-18 65.7 0.0 6.7e-18 64.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CAR29698.1 - 6.1e-06 25.2 0.0 6.1e-06 25.2 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain DUF2416 PF10315.4 CAR29699.1 - 0.073 13.3 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2416) Arrestin_C PF02752.17 CAR29701.1 - 1.5e-13 51.0 0.0 3.9e-13 49.6 0.0 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CAR29701.1 - 2.7e-08 33.7 0.0 6.7e-05 22.7 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Exo70 PF03081.10 CAR29702.1 - 6.4e-87 291.7 0.7 6.4e-87 291.7 0.5 1.8 2 0 0 2 2 2 1 Exo70 exocyst complex subunit RNA_lig_T4_1 PF09511.5 CAR29703.1 - 5.5e-78 261.4 0.0 1.1e-77 260.4 0.0 1.5 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 CAR29703.1 - 5.4e-73 244.3 0.1 1.3e-72 243.1 0.0 1.7 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.6 CAR29703.1 - 1.9e-62 210.8 0.2 3e-62 210.1 0.1 1.3 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain DUF4020 PF13212.1 CAR29703.1 - 0.069 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4020) OTCace PF00185.19 CAR29704.1 - 2.9e-44 150.7 0.3 5.5e-44 149.8 0.2 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 CAR29704.1 - 3.8e-41 140.0 0.4 1.3e-40 138.3 0.1 1.9 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain NTR2 PF15458.1 CAR29705.1 - 1.8e-16 60.1 14.2 1.8e-16 60.1 9.8 2.3 1 1 1 2 2 2 1 Nineteen complex-related protein 2 V_ATPase_I PF01496.14 CAR29705.1 - 9.8 3.8 7.1 15 3.2 4.9 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Zn_clus PF00172.13 CAR29706.1 - 1.6e-11 43.8 11.3 2.8e-11 43.1 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BRCT PF00533.21 CAR29707.1 - 2.4e-13 50.0 11.9 0.00017 21.6 0.0 4.9 4 1 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CAR29707.1 - 3.8e-12 45.8 0.2 7.6e-06 25.6 0.0 3.8 4 0 0 4 4 4 3 twin BRCT domain Perm-CXXC PF15629.1 CAR29707.1 - 0.41 10.6 5.5 0.1 12.6 1.3 1.8 2 0 0 2 2 2 0 Permuted single zf-CXXC unit GWT1 PF06423.7 CAR29708.1 - 3.1e-45 153.6 0.5 3.1e-45 153.6 0.3 2.5 3 0 0 3 3 3 1 GWT1 UvrD_C PF13361.1 CAR29709.1 - 1.8e-70 238.1 0.0 1.4e-69 235.2 0.0 2.4 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 CAR29709.1 - 1.7e-66 224.6 0.0 5.5e-66 223.0 0.0 1.9 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 CAR29709.1 - 5.3e-11 42.5 0.0 1.1e-06 28.7 0.0 2.9 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 CAR29709.1 - 1.2e-10 40.9 0.0 3e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 CAR29709.1 - 5e-06 26.2 0.1 1.8e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.9 CAR29709.1 - 0.0036 16.9 0.0 0.014 15.0 0.0 2.0 1 0 0 1 1 1 1 Helicase AAA_30 PF13604.1 CAR29709.1 - 0.0041 16.7 0.0 0.011 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Ion_trans_2 PF07885.11 CAR29710.1 - 3e-26 90.9 25.0 2.6e-17 62.3 4.9 3.5 4 0 0 4 4 4 2 Ion channel ISK_Channel PF02060.10 CAR29710.1 - 0.12 12.0 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 Slow voltage-gated potassium channel DUF2457 PF10446.4 CAR29710.1 - 0.99 8.0 10.3 1.1 7.8 5.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 CAR29710.1 - 5 6.2 7.0 7.8 5.6 4.9 1.2 1 0 0 1 1 1 0 NOA36 protein Na_H_Exchanger PF00999.16 CAR29711.1 - 2.1e-62 210.8 29.1 2.8e-62 210.4 20.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF4131 PF13567.1 CAR29711.1 - 2.3 7.5 6.2 4.5 6.6 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Pkinase PF00069.20 CAR29712.1 - 1.4e-66 224.3 0.0 2.8e-66 223.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR29712.1 - 6.6e-46 156.4 0.0 1.2e-45 155.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR29712.1 - 1.3e-12 47.3 0.0 2e-09 36.8 0.0 2.3 2 0 0 2 2 2 2 Kinase-like SAM_2 PF07647.12 CAR29712.1 - 0.0036 17.1 0.1 0.0091 15.8 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 CAR29712.1 - 0.025 14.3 0.2 0.068 12.9 0.1 1.7 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Pneumo_M2 PF07380.6 CAR29712.1 - 0.14 12.1 1.0 0.57 10.2 0.2 2.4 3 0 0 3 3 3 0 Pneumovirus M2 protein APH PF01636.18 CAR29712.1 - 0.38 10.4 0.0 0.65 9.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L21p PF00829.16 CAR29713.1 - 2.5e-05 24.3 0.1 3.1e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein PTPLA PF04387.9 CAR29714.1 - 5.5e-42 142.9 9.7 7.9e-42 142.4 6.7 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA SAPS PF04499.10 CAR29715.1 - 1.5e-172 574.5 1.3 1.5e-172 574.5 0.9 3.8 3 1 0 3 3 3 1 SIT4 phosphatase-associated protein PhzC-PhzF PF02567.11 CAR29716.1 - 1e-65 221.7 0.0 1.2e-65 221.5 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.6 CAR29716.1 - 7e-07 28.3 0.0 1.3e-06 27.4 0.0 1.4 2 0 0 2 2 2 1 Proline racemase Epimerase PF01370.16 CAR29717.1 - 3.4e-19 69.2 0.0 5.6e-19 68.5 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CAR29717.1 - 5e-13 48.3 0.0 7.5e-13 47.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CAR29717.1 - 3.9e-11 43.2 0.1 1.1e-10 41.8 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 CAR29717.1 - 2.1e-10 39.9 0.0 2.3e-09 36.5 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 CAR29717.1 - 2.4e-06 27.5 0.3 4.9e-06 26.5 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 CAR29717.1 - 5.7e-05 22.4 0.1 0.02 14.1 0.1 2.4 2 0 0 2 2 2 2 NmrA-like family KR PF08659.5 CAR29717.1 - 0.00037 20.2 0.1 0.0012 18.5 0.1 1.8 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 CAR29717.1 - 0.0057 16.7 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 CAR29717.1 - 0.017 14.0 0.1 0.025 13.4 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 CAR29717.1 - 0.026 13.4 0.0 0.053 12.4 0.0 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain F420_oxidored PF03807.12 CAR29717.1 - 0.041 14.3 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 CAR29717.1 - 0.065 12.6 0.6 0.46 9.9 0.4 2.1 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA adh_short_C2 PF13561.1 CAR29717.1 - 0.079 12.7 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase MFS_1 PF07690.11 CAR29718.1 - 3.1e-30 105.1 23.9 2.5e-28 98.8 15.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1497 PF07384.6 CAR29718.1 - 0.17 12.0 0.2 0.5 10.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1497) Oxidored_FMN PF00724.15 CAR29719.1 - 1.8e-44 152.1 0.0 4.5e-44 150.8 0.0 1.7 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family NMO PF03060.10 CAR29720.1 - 5.7e-76 255.7 0.0 7.1e-76 255.4 0.0 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 CAR29720.1 - 1.5e-08 33.9 0.1 0.00071 18.5 0.1 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.16 CAR29720.1 - 5.1e-07 28.9 2.5 7.1e-07 28.4 0.7 1.9 2 1 0 2 2 2 1 Dihydroorotate dehydrogenase NanE PF04131.9 CAR29720.1 - 7.7e-07 28.2 0.2 1.5e-06 27.3 0.0 1.5 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.16 CAR29720.1 - 0.0003 20.1 0.0 0.0034 16.6 0.0 2.1 2 0 0 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.9 CAR29720.1 - 0.0024 16.9 0.4 0.0057 15.7 0.3 1.6 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Dus PF01207.12 CAR29720.1 - 0.0029 16.4 0.0 0.0051 15.6 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DUF561 PF04481.7 CAR29720.1 - 0.015 14.2 1.3 0.016 14.1 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF561) FMN_dh PF01070.13 CAR29720.1 - 0.041 12.7 0.1 0.077 11.8 0.1 1.5 1 0 0 1 1 1 0 FMN-dependent dehydrogenase PcrB PF01884.12 CAR29720.1 - 0.1 11.8 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 PcrB family mRNA_triPase PF02940.10 CAR29721.1 - 4.9e-36 124.4 7.0 8.9e-36 123.6 4.9 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain DUF544 PF04424.8 CAR29721.1 - 1.2e-13 50.9 0.2 3.4e-13 49.4 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF544) DUF237 PF03072.9 CAR29721.1 - 0.0043 16.9 0.2 0.018 14.9 0.1 2.0 2 0 0 2 2 2 1 MG032/MG096/MG288 family 1 Membr_traf_MHD PF10540.4 CAR29723.1 - 5.4e-13 48.9 0.0 2e-12 47.0 0.0 2.1 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 CAR29723.1 - 3.8e-09 36.2 0.0 9.5e-09 34.9 0.0 1.7 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.6 CAR29723.1 - 1.4e-05 23.6 0.0 3.3e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF810) SWIB PF02201.13 CAR29724.1 - 3.3e-24 84.3 0.1 2e-23 81.8 0.0 2.0 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.6 CAR29724.1 - 1.7e-12 46.9 0.0 6.2e-12 45.1 0.0 2.0 2 0 0 2 2 2 1 DEK C terminal domain DUF2457 PF10446.4 CAR29724.1 - 1.6 7.3 23.3 0.054 12.2 10.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) DUF2076 PF09849.4 CAR29724.1 - 1.8 8.5 12.6 0.83 9.6 5.8 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) NOA36 PF06524.7 CAR29724.1 - 2 7.5 14.0 0.084 12.1 6.0 1.5 2 0 0 2 2 2 0 NOA36 protein Nucleoplasmin PF03066.10 CAR29724.1 - 5.6 6.4 19.0 5.5 6.4 11.6 2.0 2 1 0 2 2 2 0 Nucleoplasmin RRS1 PF04939.7 CAR29725.1 - 1.9e-64 216.0 6.3 2.2e-64 215.8 4.4 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) RhoGEF PF00621.15 CAR29726.1 - 1.1e-16 61.2 2.2 1.1e-16 61.2 1.5 2.8 3 0 0 3 3 3 2 RhoGEF domain DUF3407 PF11887.3 CAR29726.1 - 0.036 13.3 0.1 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3407) VPS11_C PF12451.3 CAR29727.1 - 4.3e-15 55.3 0.3 1.3e-14 53.8 0.2 1.9 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-RING_5 PF14634.1 CAR29727.1 - 0.0043 16.7 5.1 0.0043 16.7 3.5 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CAR29727.1 - 0.0044 17.0 6.3 0.012 15.5 4.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CAR29727.1 - 0.005 16.6 6.7 0.017 14.9 4.7 2.0 1 1 0 1 1 1 1 Ring finger domain PHD PF00628.24 CAR29727.1 - 0.0079 15.8 4.0 0.021 14.5 2.7 1.8 1 0 0 1 1 1 1 PHD-finger zf-Apc11 PF12861.2 CAR29727.1 - 0.036 13.9 1.1 0.071 12.9 0.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 CAR29727.1 - 0.1 12.4 7.6 0.11 12.4 3.0 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING RNase_PH_C PF03725.10 CAR29727.1 - 0.23 11.4 5.9 7.1 6.6 0.2 3.5 3 0 0 3 3 3 0 3' exoribonuclease family, domain 2 zf-rbx1 PF12678.2 CAR29727.1 - 0.29 11.2 3.7 0.63 10.1 2.5 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4 PF00097.20 CAR29727.1 - 1.9 8.1 5.9 5.2 6.8 4.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) S10_plectin PF03501.10 CAR29728.1 - 4e-42 142.0 0.5 4.6e-42 141.7 0.4 1.0 1 0 0 1 1 1 1 Plectin/S10 domain YjcQ PF09639.5 CAR29728.1 - 0.039 14.0 0.1 0.057 13.5 0.1 1.3 1 0 0 1 1 1 0 YjcQ protein tRNA-synt_1c_C PF03950.13 CAR29728.1 - 0.052 13.2 0.0 0.056 13.1 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain DUF505 PF04458.7 CAR29728.1 - 0.08 11.0 0.2 0.091 10.8 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF505) MsyB PF13984.1 CAR29728.1 - 0.13 12.3 0.0 0.18 11.8 0.0 1.3 1 1 0 1 1 1 0 MsyB protein DUF2977 PF11192.3 CAR29728.1 - 0.19 11.5 1.0 0.3 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2977) PadR PF03551.9 CAR29728.1 - 0.52 10.1 5.5 0.076 12.7 1.1 1.8 2 1 0 2 2 2 0 Transcriptional regulator PadR-like family Mpv17_PMP22 PF04117.7 CAR29729.1 - 8.9e-22 76.5 1.5 8.9e-22 76.5 1.0 2.6 2 0 0 2 2 2 1 Mpv17 / PMP22 family P5-ATPase PF12409.3 CAR29730.1 - 1.3e-35 121.7 0.0 5.4e-35 119.8 0.0 2.1 2 0 0 2 2 2 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.15 CAR29730.1 - 1.4e-27 96.2 0.0 2.6e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 CAR29730.1 - 1.5e-21 77.4 0.0 3.6e-21 76.2 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CAR29730.1 - 4.7e-16 59.8 0.0 9.1e-13 49.1 0.0 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CAR29730.1 - 6.9e-06 25.9 0.0 1.6e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CAR29730.1 - 0.0044 16.4 0.0 0.0096 15.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CAR29730.1 - 0.021 14.3 0.1 0.84 9.1 0.0 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase S1 PF00575.18 CAR29731.1 - 2.4e-61 203.7 29.6 1e-13 51.1 0.4 11.3 10 1 0 10 10 10 10 S1 RNA binding domain TPR_19 PF14559.1 CAR29731.1 - 3.9e-09 36.7 0.0 0.00086 19.5 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CAR29731.1 - 1.3e-07 31.5 0.1 0.19 12.4 0.0 4.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 CAR29731.1 - 1e-06 29.2 0.0 0.073 13.7 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CAR29731.1 - 2.6e-05 24.0 0.1 0.063 13.2 0.0 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 CAR29731.1 - 0.00012 21.6 0.0 0.42 10.2 0.0 3.0 2 1 0 2 2 2 2 TPR repeat Suf PF05843.9 CAR29731.1 - 0.015 15.0 28.6 0.028 14.1 0.0 4.8 3 1 2 5 5 5 0 Suppressor of forked protein (Suf) TPR_2 PF07719.12 CAR29731.1 - 0.026 14.4 0.4 4.5 7.4 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 CAR29731.1 - 0.072 12.8 2.6 0.12 12.1 0.2 2.4 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 TPR_15 PF13429.1 CAR29731.1 - 0.098 11.7 9.3 0.45 9.5 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat RrnaAD PF00398.15 CAR29732.1 - 1.2e-63 214.6 0.0 1.4e-63 214.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase TAFII55_N PF04658.8 CAR29733.1 - 5.2e-56 188.6 0.1 5.2e-56 188.6 0.0 2.6 2 1 0 2 2 2 1 TAFII55 protein conserved region SNF2_N PF00176.18 CAR29734.1 - 7.2e-86 287.6 0.8 7.2e-86 287.6 0.5 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CAR29734.1 - 8e-18 64.0 0.2 2.8e-16 59.1 0.0 3.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Bromodomain PF00439.20 CAR29734.1 - 6.4e-17 61.2 0.4 1.9e-16 59.7 0.3 1.8 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.1 CAR29734.1 - 7.9e-14 51.5 5.8 7.9e-14 51.5 4.0 4.6 4 1 1 5 5 5 1 Snf2-ATP coupling, chromatin remodelling complex AAA_2 PF07724.9 CAR29735.1 - 3.3e-51 173.5 0.1 4.1e-49 166.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 CAR29735.1 - 1e-24 86.2 0.8 4.1e-24 84.2 0.1 2.6 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 CAR29735.1 - 7.8e-23 81.1 0.0 9.9e-12 45.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CAR29735.1 - 6.1e-16 58.4 2.2 6.3e-12 45.4 0.0 4.2 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CAR29735.1 - 1.9e-14 54.0 3.4 0.00021 21.3 0.0 4.4 3 2 1 5 5 4 3 AAA ATPase domain AAA_22 PF13401.1 CAR29735.1 - 8.7e-10 38.8 0.1 0.00043 20.4 0.0 3.5 3 1 0 3 3 3 2 AAA domain AAA_14 PF13173.1 CAR29735.1 - 8e-08 32.2 0.0 0.023 14.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain Sigma54_activat PF00158.21 CAR29735.1 - 9.7e-07 28.4 0.1 3.5e-05 23.3 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain Arch_ATPase PF01637.13 CAR29735.1 - 1.7e-06 27.8 11.9 0.00084 19.0 0.2 4.9 3 2 0 3 3 2 1 Archaeal ATPase AAA_17 PF13207.1 CAR29735.1 - 2.5e-06 28.3 8.1 0.015 16.1 0.0 4.3 3 1 0 4 4 3 2 AAA domain IstB_IS21 PF01695.12 CAR29735.1 - 3.3e-06 26.6 0.0 0.043 13.2 0.0 3.1 3 0 0 3 3 3 2 IstB-like ATP binding protein ABC_tran PF00005.22 CAR29735.1 - 2.2e-05 24.7 0.2 0.078 13.2 0.0 3.3 3 1 0 3 3 3 1 ABC transporter AAA_18 PF13238.1 CAR29735.1 - 6e-05 23.3 7.6 0.063 13.5 0.0 3.6 3 2 0 3 3 2 2 AAA domain DUF815 PF05673.8 CAR29735.1 - 8.1e-05 21.6 1.6 0.5 9.2 0.1 3.7 2 2 0 2 2 2 2 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 CAR29735.1 - 0.00011 21.3 0.0 0.0023 17.0 0.0 2.7 2 1 0 2 2 2 1 Zeta toxin DUF258 PF03193.11 CAR29735.1 - 0.00015 21.0 0.0 0.034 13.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_28 PF13521.1 CAR29735.1 - 0.00024 21.1 0.0 0.41 10.5 0.0 3.4 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 CAR29735.1 - 0.00031 20.4 0.0 0.31 10.7 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 CAR29735.1 - 0.00038 19.9 0.0 0.086 12.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.1 CAR29735.1 - 0.00044 20.3 1.5 2.5 7.9 0.0 3.9 3 1 1 4 4 3 1 AAA domain MMR_HSR1 PF01926.18 CAR29735.1 - 0.00053 19.9 0.0 0.068 13.1 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_19 PF13245.1 CAR29735.1 - 0.00058 19.5 0.0 1.5 8.6 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain AAA_30 PF13604.1 CAR29735.1 - 0.00062 19.3 0.0 0.67 9.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 CAR29735.1 - 0.00072 19.2 0.0 0.18 11.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.17 CAR29735.1 - 0.00073 19.6 0.1 1.2 9.3 0.0 3.1 2 1 0 2 2 2 1 RNA helicase PduV-EutP PF10662.4 CAR29735.1 - 0.00083 18.8 0.0 0.46 9.9 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Mg_chelatase PF01078.16 CAR29735.1 - 0.0011 18.1 0.6 0.57 9.3 0.0 3.8 3 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI T2SE PF00437.15 CAR29735.1 - 0.0028 16.5 0.7 0.044 12.6 0.2 2.5 2 1 0 2 2 2 1 Type II/IV secretion system protein UPF0079 PF02367.12 CAR29735.1 - 0.0044 16.6 0.0 1.5 8.4 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 SRP54 PF00448.17 CAR29735.1 - 0.0071 15.8 0.1 1.1 8.6 0.0 2.8 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain ResIII PF04851.10 CAR29735.1 - 0.0077 16.0 0.1 2.3 8.0 0.0 3.5 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.4 CAR29735.1 - 0.0094 14.6 0.0 0.84 8.1 0.0 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.12 CAR29735.1 - 0.012 15.3 0.5 0.71 9.6 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function DUF87 LacI PF00356.16 CAR29735.1 - 0.013 15.1 0.0 3.2 7.4 0.0 3.1 3 0 0 3 3 2 0 Bacterial regulatory proteins, lacI family AAA_24 PF13479.1 CAR29735.1 - 0.016 14.7 0.0 6.1 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CAR29735.1 - 0.021 14.6 0.0 3.9 7.3 0.0 3.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CAR29735.1 - 0.022 14.1 3.4 3.1 7.1 0.0 3.5 3 2 0 3 3 3 0 AAA domain AAA_3 PF07726.6 CAR29735.1 - 0.026 14.1 0.1 0.54 9.8 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.12 CAR29735.1 - 0.027 14.0 0.0 3.7 7.0 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Torsin PF06309.6 CAR29735.1 - 0.032 14.1 0.0 0.084 12.7 0.0 1.7 1 0 0 1 1 1 0 Torsin PhoH PF02562.11 CAR29735.1 - 0.034 13.3 0.0 2.6 7.2 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein NTPase_1 PF03266.10 CAR29735.1 - 0.038 13.6 0.2 24 4.5 0.0 3.4 3 0 0 3 3 3 0 NTPase Miro PF08477.8 CAR29735.1 - 0.045 14.2 0.0 0.92 10.0 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein LTXXQ PF07813.7 CAR29735.1 - 2.2 8.7 7.0 1.2 9.6 1.2 3.0 3 1 1 4 4 2 0 LTXXQ motif family protein DUF972 PF06156.8 CAR29735.1 - 7.4 6.9 8.4 11 6.4 4.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) HSP20 PF00011.16 CAR29736.1 - 2e-21 75.7 4.4 2.6e-21 75.4 3.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Apc13p PF05839.6 CAR29737.1 - 1.4e-12 47.4 1.7 4.3e-11 42.6 0.6 2.1 2 0 0 2 2 2 2 Apc13p protein Cellulase PF00150.13 CAR29738.1 - 2.5e-15 56.4 4.2 5.4e-15 55.3 2.9 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PalH PF08733.5 CAR29739.1 - 1.6e-61 208.1 18.9 2.1e-61 207.7 13.1 1.1 1 0 0 1 1 1 1 PalH/RIM21 DUF3043 PF11241.3 CAR29739.1 - 0.3 10.6 2.8 0.32 10.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) TFCD_C PF12612.3 CAR29740.1 - 6.2e-07 29.0 0.6 8.3 5.7 0.1 8.0 2 2 1 3 3 3 1 Tubulin folding cofactor D C terminal F-box-like PF12937.2 CAR29740.1 - 0.00031 20.4 0.0 1e+03 -0.5 0.0 9.9 18 2 0 18 18 18 0 F-box-like Condensin2nSMC PF12422.3 CAR29740.1 - 0.0011 18.6 0.0 8.7 6.0 0.0 4.3 1 1 4 5 5 5 1 Condensin II non structural maintenance of chromosomes subunit DUF1353 PF07087.6 CAR29740.1 - 0.0022 17.4 42.5 1.2 8.6 0.8 10.4 1 1 7 8 8 8 5 Protein of unknown function (DUF1353) Fasciclin PF02469.17 CAR29740.1 - 0.034 14.1 0.2 0.15 12.0 0.1 2.1 1 1 0 1 1 1 0 Fasciclin domain Dna2 PF08696.6 CAR29740.1 - 0.15 11.3 15.1 72 2.5 0.0 8.6 2 1 8 12 12 12 0 DNA replication factor Dna2 UNC45-central PF11701.3 CAR29740.1 - 4.8 6.8 6.5 93 2.6 0.1 5.2 4 3 0 4 4 4 0 Myosin-binding striated muscle assembly central HLH PF00010.21 CAR29741.1 - 1.1e-17 63.4 0.2 3.3e-17 61.9 0.1 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain GHMP_kinases_N PF00288.21 CAR29742.1 - 1.4e-12 47.5 0.0 3e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CAR29742.1 - 3.9e-05 23.7 0.0 9.6e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal ATP-synt_C PF00137.16 CAR29743.1 - 1.5e-27 95.2 23.7 2.6e-17 62.4 5.0 2.2 2 0 0 2 2 2 2 ATP synthase subunit C Sensor_TM1 PF13755.1 CAR29743.1 - 0.11 12.0 2.1 1.4 8.4 0.3 2.5 2 0 0 2 2 2 0 Sensor N-terminal transmembrane domain PC_rep PF01851.17 CAR29744.1 - 9.8e-28 94.8 13.2 2.5e-07 30.5 0.2 9.2 9 0 0 9 9 9 6 Proteasome/cyclosome repeat Spore_coat_CotO PF14153.1 CAR29744.1 - 5 6.5 15.6 3.3 7.1 2.5 2.3 2 0 0 2 2 2 0 Spore coat protein CotO DPPIV_N PF00930.16 CAR29745.1 - 7.1e-98 327.4 4.8 9.8e-98 326.9 3.3 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 CAR29745.1 - 1e-50 171.9 2.4 1.7e-50 171.2 1.6 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CAR29745.1 - 1.8e-10 40.7 0.0 1.7e-09 37.5 0.1 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CAR29745.1 - 0.00018 21.4 0.0 0.0021 17.9 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 CAR29745.1 - 0.021 14.0 0.0 0.077 12.2 0.0 1.8 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 CAR29745.1 - 0.063 12.8 0.0 0.14 11.7 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 CAR29745.1 - 0.071 12.5 0.1 10 5.4 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Pkinase PF00069.20 CAR29746.1 - 2.2e-66 223.7 0.0 2.9e-66 223.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR29746.1 - 1.7e-30 105.9 0.0 2.9e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4558 PF15104.1 CAR29746.1 - 0.031 14.1 0.6 0.056 13.3 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4558) APH PF01636.18 CAR29746.1 - 0.044 13.5 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family PIF1 PF05970.9 CAR29747.1 - 9.2e-53 179.4 0.8 2e-43 148.7 0.2 2.3 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 CAR29747.1 - 4.8e-18 65.4 0.0 7.9e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CAR29747.1 - 4e-06 27.0 0.0 2.6e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain Herpes_Helicase PF02689.9 CAR29747.1 - 3.1e-05 21.9 0.2 0.00069 17.5 0.0 2.1 2 0 0 2 2 2 1 Helicase AAA_19 PF13245.1 CAR29747.1 - 0.00054 19.6 0.5 0.0012 18.5 0.4 1.5 1 0 0 1 1 1 1 Part of AAA domain PhoH PF02562.11 CAR29747.1 - 0.0012 18.1 0.1 0.014 14.6 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein T2SE PF00437.15 CAR29747.1 - 0.002 17.1 0.1 0.0035 16.2 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein UvrD_C_2 PF13538.1 CAR29747.1 - 0.013 15.6 0.2 0.32 11.1 0.0 2.6 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain Mg_chelatase PF01078.16 CAR29747.1 - 0.03 13.4 0.0 0.058 12.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 CAR29747.1 - 0.039 12.9 0.1 0.092 11.7 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.13 CAR29747.1 - 0.046 13.2 0.1 0.17 11.3 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.24 CAR29747.1 - 0.09 12.9 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MatE PF01554.13 CAR29748.1 - 1.1e-61 207.2 31.5 2.3e-32 111.8 7.3 2.3 2 0 0 2 2 2 2 MatE Ribosomal_L1 PF00687.16 CAR29749.1 - 2.9e-42 144.5 1.3 6e-42 143.4 0.9 1.5 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF4611 PF15387.1 CAR29749.1 - 0.9 9.7 9.7 2.3 8.4 4.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) CytochromB561_N PF09786.4 CAR29749.1 - 8.7 4.6 11.3 15 3.8 7.8 1.3 1 0 0 1 1 1 0 Cytochrome B561, N terminal Elf1 PF05129.8 CAR29750.1 - 9.6e-30 102.1 1.6 1.3e-29 101.7 1.1 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Prp19_bind PF06991.6 CAR29750.1 - 0.01 15.1 7.5 0.015 14.5 5.2 1.2 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain DUF4611 PF15387.1 CAR29750.1 - 0.043 13.9 0.7 0.043 13.9 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) FYDLN_acid PF09538.5 CAR29750.1 - 0.1 13.1 11.8 0.18 12.3 8.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CDC45 PF02724.9 CAR29750.1 - 0.38 8.7 9.2 0.47 8.4 6.4 1.2 1 0 0 1 1 1 0 CDC45-like protein zf-C2H2_6 PF13912.1 CAR29750.1 - 0.41 10.6 0.3 0.41 10.6 0.2 2.3 3 0 0 3 3 3 0 C2H2-type zinc finger eIF-3c_N PF05470.7 CAR29750.1 - 1.1 7.2 5.6 1 7.3 3.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Voldacs PF03517.8 CAR29750.1 - 2.2 8.1 9.7 0.58 9.9 0.1 2.1 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling SDA1 PF05285.7 CAR29750.1 - 3.4 6.8 19.3 4.1 6.6 13.4 1.2 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.7 CAR29750.1 - 4 5.6 15.9 5.4 5.2 11.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) COX5A PF02284.11 CAR29751.1 - 2.1e-49 165.9 1.0 3.1e-49 165.4 0.7 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DUF4294 PF14127.1 CAR29751.1 - 0.064 12.8 0.1 0.13 11.8 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4294) EIF_2_alpha PF07541.7 CAR29751.1 - 0.18 11.5 0.6 2.1 8.1 0.2 2.1 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 2 alpha subunit Calcipressin PF04847.7 CAR29752.1 - 5.3e-17 61.9 0.4 1e-16 61.0 0.3 1.4 1 1 0 1 1 1 1 Calcipressin Nramp PF01566.13 CAR29753.1 - 1.8e-91 306.6 15.0 2.2e-91 306.3 9.2 1.7 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein DUF4342 PF14242.1 CAR29753.1 - 0.79 9.5 2.7 1.9 8.3 1.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4342) FSH1 PF03959.8 CAR29754.1 - 1.5e-61 207.5 0.0 1.7e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 CAR29754.1 - 1.8e-05 24.5 0.0 3.8e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CAR29754.1 - 0.00014 21.8 0.0 0.3 10.9 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CAR29754.1 - 0.0014 18.1 0.0 1 8.7 0.0 2.5 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase BAAT_C PF08840.6 CAR29754.1 - 0.011 15.5 0.0 4 7.0 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2456 PF10445.4 CAR29755.1 - 0.0072 16.2 0.1 0.019 14.8 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2456) DUF2781 PF10914.3 CAR29755.1 - 0.008 15.9 1.7 0.008 15.9 1.2 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2781) TauE PF01925.14 CAR29755.1 - 0.049 13.0 9.6 0.2 11.1 6.7 1.8 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE DUF1049 PF06305.6 CAR29755.1 - 0.72 9.3 6.3 11 5.5 0.0 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1049) MFS_1 PF07690.11 CAR29756.1 - 4.4e-32 111.1 33.0 4.4e-32 111.1 22.9 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M1 PF01433.15 CAR29757.1 - 3.6e-143 477.3 2.6 4.8e-143 476.9 1.8 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 CAR29757.1 - 7e-92 308.1 3.8 1.3e-91 307.1 2.6 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 CAR29757.1 - 1.1e-20 73.9 0.3 2.6e-20 72.7 0.2 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily ODR4-like PF14778.1 CAR29757.1 - 0.019 13.7 0.0 0.033 12.8 0.0 1.3 1 0 0 1 1 1 0 Olfactory receptor 4-like Inositol_P PF00459.20 CAR29758.1 - 1.7e-65 221.0 0.0 1.9e-65 220.8 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family RNase_H2-Ydr279 PF09468.5 CAR29760.1 - 1.6e-51 175.3 2.6 1.8e-51 175.1 1.8 1.0 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) PRANC PF09372.5 CAR29760.1 - 0.071 13.0 0.4 0.53 10.2 0.1 2.4 2 0 0 2 2 2 0 PRANC domain RNase_PH PF01138.16 CAR29761.1 - 3e-19 69.6 0.0 4.6e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CAR29761.1 - 2.5e-10 40.1 0.0 1.2e-09 37.9 0.0 2.1 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 HAD_2 PF13419.1 CAR29763.1 - 4.4e-11 43.3 0.0 7.3e-11 42.5 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CAR29763.1 - 5.3e-06 26.0 0.0 9.7e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CAR29763.1 - 9.3e-05 22.9 0.0 0.016 15.6 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CAR29763.1 - 0.0066 16.6 0.0 0.0086 16.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF155 PF02582.9 CAR29764.1 - 1.2e-43 149.0 0.0 1.7e-43 148.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 FAD_binding_1 PF00667.15 CAR29765.1 - 1.3e-65 220.8 0.0 2.3e-65 220.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CAR29765.1 - 1.8e-27 96.0 1.1 3.1e-27 95.3 0.7 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 CAR29765.1 - 3.1e-21 75.9 0.1 1.8e-20 73.5 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 CAR29765.1 - 0.021 14.8 0.1 0.15 12.0 0.1 2.3 1 1 1 2 2 2 0 Flavodoxin domain Spore_IV_A PF09547.5 CAR29765.1 - 0.036 12.7 0.0 0.061 12.0 0.0 1.2 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) MAGE PF01454.14 CAR29766.1 - 1.6e-34 118.9 0.1 2.2e-34 118.5 0.1 1.2 1 0 0 1 1 1 1 MAGE family Inositol_P PF00459.20 CAR29767.1 - 1.4e-69 234.4 0.0 1.6e-69 234.2 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF836 PF05768.9 CAR29768.1 - 2.6e-15 56.4 0.1 3e-15 56.2 0.1 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.19 CAR29768.1 - 0.011 15.6 0.1 0.017 15.0 0.1 1.4 1 0 0 1 1 1 0 Glutaredoxin Thioredoxin_3 PF13192.1 CAR29768.1 - 0.029 14.1 0.0 0.039 13.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_2 PF13098.1 CAR29768.1 - 0.042 14.0 0.0 0.044 13.9 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain Ras_bdg_2 PF14847.1 CAR29768.1 - 0.089 12.7 0.0 0.12 12.3 0.0 1.3 1 1 0 1 1 1 0 Ras-binding domain of Byr2 PAP2 PF01569.16 CAR29770.1 - 1.3e-19 70.1 0.5 1.3e-19 70.1 0.4 2.2 2 1 1 3 3 3 1 PAP2 superfamily MFS_1 PF07690.11 CAR29770.1 - 0.5 9.0 4.6 0.26 9.9 0.8 1.9 2 0 0 2 2 2 0 Major Facilitator Superfamily HGTP_anticodon2 PF12745.2 CAR29771.1 - 1.6e-97 325.9 0.1 1.6e-97 325.9 0.1 2.7 3 0 0 3 3 3 1 Anticodon binding domain of tRNAs Pkinase PF00069.20 CAR29771.1 - 2.8e-67 226.6 10.5 5.6e-46 156.7 0.1 4.4 4 1 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 CAR29771.1 - 1.6e-39 135.5 0.2 2.1e-23 82.7 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.17 CAR29771.1 - 8.6e-16 57.8 4.9 2.9e-15 56.1 3.4 2.0 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.1 CAR29771.1 - 4.7e-15 55.4 0.0 1.3e-14 53.9 0.0 1.8 2 0 0 2 2 2 1 Histidyl-tRNA synthetase Kinase-like PF14531.1 CAR29771.1 - 0.0044 16.0 0.1 0.27 10.1 0.0 3.1 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 CAR29771.1 - 0.02 14.6 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Med20 PF08612.6 CAR29772.1 - 2.6e-44 151.0 0.0 2.8e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex FtsZ_C PF12327.3 CAR29772.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 FtsZ family, C-terminal domain CTD_bind PF04818.8 CAR29773.1 - 6.4e-19 67.9 0.4 1.5e-18 66.7 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CTK3 PF12243.3 CAR29773.1 - 0.00069 19.2 1.8 0.0013 18.4 0.1 2.0 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 Cor1 PF04803.7 CAR29773.1 - 0.0012 18.5 4.9 0.085 12.6 2.3 3.3 2 1 0 2 2 2 1 Cor1/Xlr/Xmr conserved region DUF1313 PF07011.6 CAR29773.1 - 0.0063 16.1 0.6 0.056 13.1 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1313) DUF3950 PF13132.1 CAR29773.1 - 0.084 12.4 0.1 0.42 10.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3950) DEAD PF00270.24 CAR29774.1 - 7.7e-25 87.3 0.1 4.6e-22 78.2 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase DUF1998 PF09369.5 CAR29774.1 - 9.7e-16 58.1 0.1 3.1e-15 56.5 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 CAR29774.1 - 2e-11 43.5 0.0 1.5e-10 40.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CDT1 PF08839.6 CAR29774.1 - 0.0043 17.0 2.0 0.011 15.6 0.4 2.5 3 0 0 3 3 3 1 DNA replication factor CDT1 like SRX PF09201.5 CAR29775.1 - 5.6e-54 181.8 0.0 1.2e-53 180.7 0.0 1.6 1 0 0 1 1 1 1 SRX SRP54 PF00448.17 CAR29775.1 - 4.5e-47 160.0 0.1 1e-44 152.3 0.1 2.3 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 CAR29775.1 - 4.3e-09 36.1 6.2 9.5e-09 35.0 4.3 1.5 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal CbiA PF01656.18 CAR29775.1 - 1.2e-06 28.1 0.0 2.7e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54_N PF02881.14 CAR29775.1 - 2.7e-06 27.3 2.3 6.5e-06 26.1 0.2 2.5 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain ArsA_ATPase PF02374.10 CAR29775.1 - 0.00048 19.2 0.2 0.021 13.8 0.1 2.4 1 1 0 1 1 1 1 Anion-transporting ATPase ArgK PF03308.11 CAR29775.1 - 0.00058 18.7 0.2 0.0017 17.1 0.0 1.9 2 1 0 2 2 2 1 ArgK protein MobB PF03205.9 CAR29775.1 - 0.00091 18.9 0.2 0.0044 16.7 0.0 2.2 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 CAR29775.1 - 0.024 14.7 0.1 0.19 11.8 0.0 2.5 1 1 2 3 3 3 0 AAA domain Cyt-b5 PF00173.23 CAR29776.1 - 6.7e-15 54.6 0.0 1.3e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-HIT PF04438.11 CAR29777.1 - 3.5e-09 36.1 8.5 6.2e-09 35.3 5.9 1.4 1 0 0 1 1 1 1 HIT zinc finger CDC45 PF02724.9 CAR29777.1 - 0.73 7.7 12.7 1.3 6.9 8.8 1.4 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 CAR29777.1 - 0.84 8.9 9.2 1.6 8.0 6.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Sporozoite_P67 PF05642.6 CAR29777.1 - 3.8 5.2 9.8 5.7 4.6 6.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.7 CAR29777.1 - 5.8 4.7 16.4 9.8 3.9 11.3 1.3 1 0 0 1 1 1 0 Nop14-like family V-ATPase_G PF03179.10 CAR29778.1 - 2.7e-31 107.9 12.7 3e-31 107.8 8.8 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DFF40 PF09230.5 CAR29778.1 - 0.03 13.6 5.0 0.032 13.5 3.5 1.0 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa Prominin PF05478.6 CAR29778.1 - 0.042 11.4 1.5 0.048 11.2 1.0 1.0 1 0 0 1 1 1 0 Prominin ATP-synt_B PF00430.13 CAR29778.1 - 0.22 11.3 16.7 0.19 11.5 9.2 1.9 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) DUF2203 PF09969.4 CAR29778.1 - 0.23 11.6 4.1 0.35 11.1 2.8 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) PTPlike_phytase PF14566.1 CAR29778.1 - 0.28 11.2 2.8 0.32 11.0 1.9 1.1 1 0 0 1 1 1 0 Inositol hexakisphosphate GA PF01468.12 CAR29778.1 - 0.59 10.3 7.2 0.73 10.0 4.2 1.9 1 1 0 1 1 1 0 GA module YlqD PF11068.3 CAR29778.1 - 1.2 9.1 9.6 1.5 8.8 6.1 1.5 1 1 0 1 1 1 0 YlqD protein KfrA_N PF11740.3 CAR29778.1 - 1.4 9.3 8.5 0.9 10.0 3.7 2.0 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term IncA PF04156.9 CAR29778.1 - 1.6 8.3 6.8 2.4 7.7 4.7 1.3 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 CAR29778.1 - 1.7 7.6 8.5 2.1 7.3 5.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3552 PF12072.3 CAR29778.1 - 2.1 7.5 17.6 0.17 11.0 7.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DUF4407 PF14362.1 CAR29778.1 - 4.5 6.1 9.1 5.6 5.8 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atrophin-1 PF03154.10 CAR29778.1 - 6.3 4.8 7.5 7 4.6 5.2 1.0 1 0 0 1 1 1 0 Atrophin-1 family vATP-synt_E PF01991.13 CAR29778.1 - 6.7 5.9 16.8 28 3.9 11.6 1.7 1 1 0 1 1 1 0 ATP synthase (E/31 kDa) subunit DUF883 PF05957.8 CAR29778.1 - 9.1 6.7 8.9 21 5.6 2.9 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Aldedh PF00171.17 CAR29779.1 - 1.2e-121 406.2 0.0 1.4e-121 406.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Antimicrobial15 PF08110.7 CAR29779.1 - 0.056 13.4 1.3 2.6 8.2 0.0 3.3 3 0 0 3 3 3 0 Ocellatin family RRF PF01765.14 CAR29780.1 - 7.7e-39 132.7 5.9 1.3e-38 132.0 4.1 1.3 1 0 0 1 1 1 1 Ribosome recycling factor BCDHK_Adom3 PF10436.4 CAR29780.1 - 0.041 13.3 0.5 0.43 10.0 0.4 2.5 1 1 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase BCL_N PF04714.8 CAR29780.1 - 0.29 10.7 2.7 11 5.6 0.0 2.7 2 0 0 2 2 2 0 BCL7, N-terminal conserver region DUF3437 PF11919.3 CAR29780.1 - 0.3 10.8 3.2 1.2 8.8 0.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3437) ApoO PF09769.4 CAR29780.1 - 0.6 9.7 3.8 0.57 9.8 0.4 2.3 2 1 0 2 2 2 0 Apolipoprotein O Mnd1 PF03962.10 CAR29780.1 - 1.3 8.5 11.3 0.098 12.3 2.3 2.1 2 0 0 2 2 2 0 Mnd1 family NPV_P10 PF05531.7 CAR29780.1 - 3.3 8.0 6.5 0.98 9.7 1.9 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4446 PF14584.1 CAR29780.1 - 5.7 6.7 7.1 1.8 8.4 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) IMD PF08397.6 CAR29780.1 - 7.4 5.8 12.6 0.68 9.2 3.2 2.2 2 0 0 2 2 2 0 IRSp53/MIM homology domain RNB PF00773.14 CAR29781.1 - 1.6e-52 178.8 0.0 1.6e-52 178.8 0.0 2.5 3 0 0 3 3 3 1 RNB domain OB_RNB PF08206.6 CAR29781.1 - 0.0075 15.7 0.1 4.7 6.7 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease B OB domain Aldedh PF00171.17 CAR29782.1 - 7.7e-101 337.7 0.0 9.4e-101 337.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family UPF0449 PF15136.1 CAR29782.1 - 0.024 14.8 0.1 0.066 13.4 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Brr6_like_C_C PF10104.4 CAR29783.1 - 5.3e-41 139.2 1.0 7.6e-41 138.7 0.7 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Pyridoxal_deC PF00282.14 CAR29784.1 - 1.8e-23 82.6 0.0 2.6e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 CAR29784.1 - 7.5e-09 34.7 0.0 2.3e-08 33.2 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 CAR29784.1 - 3.6e-06 26.2 0.0 5.7e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family HDA2-3 PF11496.3 CAR29785.1 - 3.3e-77 259.2 1.6 3.3e-77 259.2 1.1 1.8 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 TBPIP PF07106.8 CAR29785.1 - 0.13 11.7 16.5 0.29 10.6 2.5 2.6 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) V_ATPase_I PF01496.14 CAR29785.1 - 0.37 8.5 8.2 0.57 7.9 5.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 CAR29785.1 - 0.71 10.2 15.1 0.11 12.8 3.9 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF972) DUF904 PF06005.7 CAR29785.1 - 1.4 9.2 17.5 1.1 9.6 4.3 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF904) DivIC PF04977.10 CAR29785.1 - 1.4 8.4 18.3 2.5 7.6 3.7 3.9 2 1 2 4 4 4 0 Septum formation initiator Sec23_trunk PF04811.10 CAR29786.1 - 6.9e-11 41.9 0.1 1.4e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 CAR29786.1 - 1.2e-06 28.8 0.0 2.7e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.10 CAR29786.1 - 1.6e-06 27.4 0.1 5e-06 25.8 0.0 1.9 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 CAR29786.1 - 0.0003 20.2 1.3 0.00083 18.8 0.9 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 CAR29786.1 - 0.011 15.4 0.0 0.025 14.2 0.0 1.7 1 1 0 1 1 1 0 Gelsolin repeat ORC2 PF04084.9 CAR29786.1 - 0.014 14.3 0.9 0.16 10.8 0.0 2.6 3 0 0 3 3 3 0 Origin recognition complex subunit 2 PHD PF00628.24 CAR29786.1 - 0.41 10.3 2.9 3.9 7.2 0.3 2.4 2 0 0 2 2 2 0 PHD-finger Mhr1 PF12829.2 CAR29787.1 - 1.3e-38 130.7 1.9 3.1e-38 129.4 1.3 1.7 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination Mmp37 PF09139.6 CAR29787.1 - 0.047 12.7 0.0 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 FA_hydroxylase PF04116.8 CAR29788.1 - 4.1e-16 59.4 8.3 4.1e-16 59.4 5.7 2.6 3 1 0 3 3 3 1 Fatty acid hydroxylase superfamily OSCP PF00213.13 CAR29789.1 - 1.7e-42 145.2 3.2 1.9e-42 145.0 2.2 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Pam16 PF03656.8 CAR29790.1 - 4.1e-42 142.9 0.7 4.9e-42 142.7 0.5 1.0 1 0 0 1 1 1 1 Pam16 PHD PF00628.24 CAR29791.1 - 2.7e-10 39.7 8.0 6e-10 38.6 5.6 1.6 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 CAR29791.1 - 4.8e-08 33.4 2.5 8.7e-07 29.3 0.0 3.7 4 0 0 4 4 4 1 SET domain PHD_2 PF13831.1 CAR29791.1 - 0.0037 16.5 3.7 0.0074 15.5 2.5 1.4 1 0 0 1 1 1 1 PHD-finger Pkinase PF00069.20 CAR29792.1 - 2.3e-54 184.2 0.1 4.6e-52 176.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAR29792.1 - 1.6e-26 92.9 0.6 1e-24 87.0 0.0 2.9 2 1 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CAR29792.1 - 0.00019 20.4 0.0 0.00032 19.6 0.0 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kdo PF06293.9 CAR29792.1 - 0.11 11.5 0.1 0.21 10.5 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1212 PF06738.7 CAR29793.1 - 3.5e-48 163.6 10.9 1.8e-44 151.5 1.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 CAR29793.1 - 2e-25 89.2 7.9 2e-25 89.2 5.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) BP28CT PF08146.7 CAR29794.1 - 1.5e-42 144.9 1.5 1.5e-42 144.9 1.1 3.8 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 CAR29794.1 - 9.3e-24 83.6 1.2 9.3e-24 83.6 0.8 4.0 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.1 CAR29794.1 - 0.01 16.0 1.8 9.5 6.5 0.0 5.1 5 0 0 5 5 5 0 HEAT repeats NuA4 PF09340.5 CAR29795.1 - 2e-21 75.3 8.8 3.7e-20 71.3 6.1 2.0 1 1 0 1 1 1 1 Histone acetyltransferase subunit NuA4 DWNN PF08783.6 CAR29795.1 - 0.025 14.5 0.4 0.16 11.9 0.1 2.0 2 0 0 2 2 2 0 DWNN domain IncA PF04156.9 CAR29795.1 - 0.058 12.9 0.4 0.079 12.5 0.3 1.2 1 0 0 1 1 1 0 IncA protein Actin PF00022.14 CAR29796.1 - 2.3e-50 171.1 0.5 4.2e-39 134.0 0.0 2.0 2 0 0 2 2 2 2 Actin MreB_Mbl PF06723.8 CAR29796.1 - 7.5e-05 21.4 0.0 0.04 12.5 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein Gln-synt_C PF00120.19 CAR29797.1 - 1.6e-62 210.9 0.0 2e-62 210.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 CAR29797.1 - 1.6e-19 69.2 0.0 2.8e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain MVL PF12151.3 CAR29797.1 - 0.1 12.3 0.8 0.29 10.8 0.0 2.1 2 0 0 2 2 2 0 Mannan-binding protein V-ATPase_H_N PF03224.9 CAR29798.1 - 3.3e-56 190.6 11.8 5.8e-56 189.8 8.2 1.4 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 CAR29798.1 - 7.5e-39 132.3 0.3 7.5e-39 132.3 0.2 2.8 2 2 2 4 4 4 1 V-ATPase subunit H IncA PF04156.9 CAR29798.1 - 0.012 15.2 2.8 0.035 13.6 1.9 1.8 1 1 0 1 1 1 0 IncA protein TMF_TATA_bd PF12325.3 CAR29798.1 - 0.028 14.1 0.4 0.088 12.5 0.2 1.9 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding HEAT_2 PF13646.1 CAR29798.1 - 0.03 14.5 0.1 19 5.6 0.0 3.1 2 1 0 2 2 2 0 HEAT repeats GatB_Yqey PF02637.13 CAR29798.1 - 0.098 12.3 0.1 0.098 12.3 0.1 2.9 4 0 0 4 4 4 0 GatB domain PCI PF01399.22 CAR29799.1 - 4.9e-10 39.6 0.1 1.6e-09 37.9 0.1 1.9 1 0 0 1 1 1 1 PCI domain Acetyltransf_2 PF00797.12 CAR29799.1 - 0.051 13.1 0.1 0.084 12.4 0.1 1.2 1 0 0 1 1 1 0 N-acetyltransferase TPR_12 PF13424.1 CAR29799.1 - 0.11 12.4 1.0 0.4 10.6 0.6 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 CAR29799.1 - 0.17 11.8 1.5 0.47 10.5 1.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Tmemb_14 PF03647.8 CAR29800.1 - 9.4e-26 90.0 6.9 1.1e-25 89.8 4.8 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF2648 PF10855.3 CAR29800.1 - 0.092 12.1 0.4 0.29 10.5 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2648) G-gamma PF00631.17 CAR29801.1 - 8.5e-23 79.8 0.0 1.1e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 GGL domain Evr1_Alr PF04777.8 CAR29802.1 - 4e-26 90.7 0.4 6.1e-26 90.1 0.3 1.3 1 0 0 1 1 1 1 Erv1 / Alr family Med27 PF11571.3 CAR29802.1 - 0.011 15.8 0.2 0.017 15.2 0.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 27 TIP41 PF04176.8 CAR29803.1 - 1.1e-71 239.8 2.3 1.5e-71 239.4 1.6 1.2 1 0 0 1 1 1 1 TIP41-like family TPR_2 PF07719.12 CAR29804.1 - 2e-06 27.2 0.0 1.4e-05 24.5 0.0 2.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 CAR29804.1 - 4.3e-06 27.2 0.4 0.0062 17.1 0.2 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 CAR29804.1 - 8.8e-06 25.2 0.5 8.2e-05 22.1 0.3 2.5 2 1 1 3 3 3 1 TPR repeat TPR_14 PF13428.1 CAR29804.1 - 0.00018 21.8 0.0 0.0011 19.4 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CAR29804.1 - 0.00038 20.0 0.4 0.0041 16.8 0.0 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 CAR29804.1 - 0.0043 17.3 0.0 0.04 14.2 0.0 2.3 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.1 CAR29804.1 - 0.0048 16.7 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 CAR29804.1 - 0.0054 16.3 0.0 0.02 14.5 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 CAR29804.1 - 0.022 14.9 0.5 2.5 8.5 0.0 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 CAR29804.1 - 0.027 14.6 0.2 0.28 11.3 0.0 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CAR29804.1 - 0.034 14.6 2.5 0.59 10.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 CAR29804.1 - 0.051 13.5 0.4 0.62 10.0 0.1 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat eIF-5_eIF-2B PF01873.12 CAR29805.1 - 6.2e-42 142.2 0.0 1.1e-41 141.4 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 CAR29805.1 - 8.2e-28 96.1 4.1 1.4e-27 95.4 0.1 2.9 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon F-box-like PF12937.2 CAR29806.1 - 6.1e-09 35.4 0.6 1.8e-08 33.9 0.4 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CAR29806.1 - 5.9e-06 25.8 1.9 7.2e-06 25.5 0.3 2.1 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.2 CAR29806.1 - 0.00022 20.7 6.8 1.2 8.8 1.0 6.0 4 2 2 6 6 6 1 Leucine Rich repeats (2 copies) DUF1699 PF08004.6 CAR29806.1 - 0.0068 15.9 1.3 0.61 9.6 0.0 3.8 4 0 0 4 4 4 1 Protein of unknown function (DUF1699) AsnA PF03590.10 CAR29806.1 - 0.02 14.3 0.0 0.044 13.2 0.0 1.5 1 0 0 1 1 1 0 Aspartate-ammonia ligase LRR_1 PF00560.28 CAR29806.1 - 0.023 14.6 14.0 1.4 9.2 0.1 7.5 6 1 0 6 6 6 0 Leucine Rich Repeat LRR_7 PF13504.1 CAR29806.1 - 0.18 12.1 1.5 12 6.6 0.0 4.6 3 0 0 3 3 3 0 Leucine rich repeat LRR_6 PF13516.1 CAR29806.1 - 0.19 11.9 15.7 2.9 8.2 0.0 7.0 7 1 1 8 8 8 0 Leucine Rich repeat PUF PF00806.14 CAR29807.1 - 1.3e-27 93.6 1.8 0.00023 20.4 0.0 6.8 7 0 0 7 7 7 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 CAR29807.1 - 1.1e-07 31.3 0.0 3.3e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR29807.1 - 2.9e-06 27.0 0.0 6.8e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR29807.1 - 0.002 18.1 0.0 0.0047 16.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Anillin PF08174.6 CAR29808.1 - 3.8e-16 59.3 0.2 1.5e-15 57.4 0.1 2.1 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 CAR29808.1 - 0.0034 17.5 0.0 0.011 15.9 0.0 2.0 1 0 0 1 1 1 1 PH domain Fip1 PF05182.8 CAR29809.1 - 1.2e-21 75.6 1.1 2.5e-21 74.6 0.8 1.5 1 0 0 1 1 1 1 Fip1 motif TFIIF_alpha PF05793.7 CAR29809.1 - 1.8 6.8 14.2 2.3 6.5 9.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF605 PF04652.11 CAR29809.1 - 5.9 6.1 13.4 7.4 5.8 9.3 1.1 1 0 0 1 1 1 0 Vta1 like Fungal_trans PF04082.13 CAR29810.1 - 2.5e-29 101.9 4.4 2.5e-29 101.9 3.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR29810.1 - 3.9e-08 33.0 10.7 6.7e-08 32.3 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L37ae PF01780.14 CAR29812.1 - 2.7e-38 129.7 9.3 3e-38 129.5 6.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 CAR29812.1 - 0.008 15.9 3.1 0.013 15.2 2.1 1.5 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DUF1364 PF07102.7 CAR29812.1 - 0.013 15.3 1.1 0.017 14.9 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) CarbpepA_inh PF02977.10 CAR29812.1 - 0.042 13.4 4.0 0.056 13.0 0.8 2.1 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor Sgf11 PF08209.6 CAR29812.1 - 0.044 13.1 0.4 1.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Rep_fac-A_C PF08646.5 CAR29812.1 - 0.086 12.5 0.2 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 Replication factor-A C terminal domain zf-H2C2_2 PF13465.1 CAR29812.1 - 0.14 12.4 0.5 2.5 8.5 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger double domain Elf1 PF05129.8 CAR29812.1 - 0.15 11.7 2.0 0.38 10.4 1.4 1.7 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like C1_1 PF00130.17 CAR29812.1 - 0.17 11.6 1.5 0.26 11.0 1.1 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-BED PF02892.10 CAR29812.1 - 0.28 10.9 4.0 6.7 6.5 0.2 2.3 1 1 1 2 2 2 0 BED zinc finger OrfB_Zn_ribbon PF07282.6 CAR29812.1 - 0.7 9.5 2.9 1.1 9.0 2.0 1.4 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zf-C4_ClpX PF06689.8 CAR29812.1 - 1.3 8.6 5.0 4 7.0 3.5 1.9 1 1 0 1 1 1 0 ClpX C4-type zinc finger Mito_carr PF00153.22 CAR29813.1 - 6.9e-71 234.0 0.5 2.2e-22 78.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Aldo_ket_red PF00248.16 CAR29814.1 - 5.3e-47 159.9 0.0 6.6e-47 159.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family RTP PF02334.11 CAR29814.1 - 0.13 12.1 0.1 0.44 10.5 0.0 1.8 2 0 0 2 2 2 0 Replication terminator protein Peptidase_C12 PF01088.16 CAR29815.1 - 1.2e-47 161.8 0.0 1.4e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 SAC3_GANP PF03399.11 CAR29816.1 - 1.8e-49 168.0 3.9 2.3e-49 167.7 2.7 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI PF01399.22 CAR29816.1 - 0.23 11.8 3.7 0.33 11.2 0.5 2.6 1 1 1 2 2 2 0 PCI domain Scramblase PF03803.10 CAR29817.1 - 6.9e-68 228.0 0.1 1.9e-33 115.3 0.0 2.0 2 0 0 2 2 2 2 Scramblase Sod_Fe_C PF02777.13 CAR29818.1 - 4.2e-11 42.6 1.3 7.2e-05 22.5 0.4 2.2 1 1 1 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain ESCRT-II PF05871.7 CAR29819.1 - 5.8e-47 159.1 0.2 6.9e-47 158.8 0.2 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit FUSC PF04632.7 CAR29820.1 - 0.18 10.2 5.9 0.21 9.9 4.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Reo_sigmaC PF04582.7 CAR29820.1 - 0.18 10.9 2.0 0.25 10.4 1.3 1.3 1 1 0 1 1 1 0 Reovirus sigma C capsid protein IFT57 PF10498.4 CAR29820.1 - 0.22 10.2 10.7 0.26 9.9 7.4 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF489 PF04356.7 CAR29820.1 - 0.46 10.0 5.5 0.44 10.1 1.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF489) YtzH PF14165.1 CAR29820.1 - 0.66 10.2 5.7 1.4 9.1 1.2 2.4 2 0 0 2 2 2 0 YtzH-like protein DDE_Tnp_IS66 PF03050.9 CAR29820.1 - 1.6 7.9 11.3 0.32 10.1 1.6 2.0 1 1 1 2 2 2 0 Transposase IS66 family CTP_synth_N PF06418.9 CAR29821.1 - 5.2e-119 396.4 0.4 6.8e-119 396.0 0.2 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 CAR29821.1 - 5.3e-58 195.6 0.0 8e-58 195.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CAR29821.1 - 4.5e-05 23.0 0.0 0.00014 21.3 0.0 1.9 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 CAR29821.1 - 0.035 13.5 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Sod_Cu PF00080.15 CAR29822.1 - 5e-43 146.6 3.8 5.8e-43 146.4 2.6 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) ER_lumen_recept PF00810.13 CAR29823.1 - 2.6e-50 170.7 13.9 3.9e-50 170.1 9.6 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor Proteasome PF00227.21 CAR29824.1 - 4.2e-35 120.7 0.1 2.4e-34 118.2 0.1 1.8 1 1 0 1 1 1 1 Proteasome subunit Transp_cyt_pur PF02133.10 CAR29825.1 - 8.7e-152 505.6 35.5 1e-151 505.4 24.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Menin PF05053.8 CAR29826.1 - 0.0086 14.2 0.7 0.011 13.9 0.5 1.1 1 0 0 1 1 1 1 Menin ResIII PF04851.10 CAR29826.1 - 0.058 13.2 0.6 0.079 12.7 0.4 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DDHD PF02862.12 CAR29826.1 - 0.08 12.7 2.3 0.13 12.0 1.6 1.4 1 0 0 1 1 1 0 DDHD domain PI3K_1B_p101 PF10486.4 CAR29826.1 - 4.8 4.6 15.0 1.2 6.6 4.9 2.2 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TFIIF_alpha PF05793.7 CAR29826.1 - 8.7 4.5 24.6 0.35 9.1 9.7 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Peptidase_M16_C PF05193.16 CAR29827.1 - 2.3e-26 92.6 0.1 5.9e-26 91.2 0.0 1.7 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CAR29827.1 - 7.5e-22 77.6 0.0 1.5e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) PPP4R2 PF09184.6 CAR29828.1 - 1.7e-51 175.4 17.3 1.7e-51 175.4 12.0 1.7 2 0 0 2 2 2 1 PPP4R2 Nop14 PF04147.7 CAR29828.1 - 0.0092 13.9 30.9 0.012 13.5 21.4 1.2 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 CAR29828.1 - 1.8 6.5 23.8 3 5.7 16.5 1.3 1 0 0 1 1 1 0 CDC45-like protein YqfQ PF14181.1 CAR29828.1 - 2.3 8.2 12.6 4.9 7.1 8.8 1.6 1 0 0 1 1 1 0 YqfQ-like protein Daxx PF03344.10 CAR29828.1 - 3.2 6.1 30.7 4.6 5.6 21.3 1.3 1 0 0 1 1 1 0 Daxx Family Ribosomal_S7 PF00177.16 CAR29829.1 - 3.2e-31 107.9 0.0 4.8e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e MA3 PF02847.12 CAR29829.1 - 0.058 13.1 0.2 3.7 7.2 0.0 2.3 2 0 0 2 2 2 0 MA3 domain EF-hand_4 PF12763.2 CAR29830.1 - 1.6e-27 95.2 0.0 4.2e-08 32.8 0.0 3.6 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 CAR29830.1 - 4.6e-11 42.6 0.0 0.022 14.9 0.0 3.7 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 CAR29830.1 - 4.6e-11 41.1 0.0 0.0069 15.6 0.0 3.9 3 0 0 3 3 3 2 EF hand UBA PF00627.26 CAR29830.1 - 1.3e-09 37.5 0.2 3.6e-09 36.1 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_6 PF13405.1 CAR29830.1 - 1.8e-07 30.4 0.0 0.92 9.5 0.0 3.9 4 0 0 4 4 3 3 EF-hand domain UBA_4 PF14555.1 CAR29830.1 - 0.00072 19.0 0.1 0.0019 17.6 0.1 1.7 1 0 0 1 1 1 1 UBA-like domain EF-hand_5 PF13202.1 CAR29830.1 - 0.00091 18.4 0.0 5.4 6.5 0.0 3.7 3 0 0 3 3 3 1 EF hand AAA_13 PF13166.1 CAR29830.1 - 0.0024 16.4 29.3 0.0024 16.4 20.3 2.1 1 1 1 2 2 2 1 AAA domain BLOC1_2 PF10046.4 CAR29830.1 - 0.008 16.2 32.9 0.018 15.1 5.9 3.6 2 1 1 3 3 3 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 EF-hand_8 PF13833.1 CAR29830.1 - 0.024 14.2 0.2 15 5.3 0.0 3.9 4 1 1 5 5 4 0 EF-hand domain pair DUF3584 PF12128.3 CAR29830.1 - 0.025 11.9 47.7 0.036 11.3 33.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Myosin_tail_1 PF01576.14 CAR29830.1 - 0.072 10.8 48.5 0.14 9.8 31.7 1.9 1 1 0 1 1 1 0 Myosin tail DUF3552 PF12072.3 CAR29830.1 - 0.22 10.7 43.4 0.031 13.5 8.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) CENP-F_leu_zip PF10473.4 CAR29830.1 - 0.24 11.2 50.2 0.027 14.3 18.6 3.2 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 CAR29830.1 - 0.4 9.7 21.5 2.3 7.3 10.4 2.9 1 1 1 3 3 3 0 Reovirus sigma C capsid protein Lebercilin PF15619.1 CAR29830.1 - 0.46 9.8 55.3 0.056 12.8 15.7 3.1 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Tropomyosin_1 PF12718.2 CAR29830.1 - 1.6 8.5 51.5 0.041 13.7 15.9 3.3 1 1 2 3 3 3 0 Tropomyosin like AAA_27 PF13514.1 CAR29830.1 - 2.8 5.5 40.3 5.8 4.4 27.9 1.4 1 0 0 1 1 1 0 AAA domain GAS PF13851.1 CAR29830.1 - 4.9 6.3 49.4 3.6 6.7 15.0 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding WEMBL PF05701.6 CAR29830.1 - 5.2 5.4 48.1 7.8 4.8 33.4 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DUF869 PF05911.6 CAR29830.1 - 5.6 5.0 43.6 47 2.0 30.3 1.7 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) Atg14 PF10186.4 CAR29830.1 - 5.8 5.7 48.2 0.065 12.1 5.6 3.2 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Tropomyosin PF00261.15 CAR29830.1 - 6.2 5.8 46.9 0.55 9.2 25.6 2.2 1 1 1 2 2 2 0 Tropomyosin APG6 PF04111.7 CAR29830.1 - 6.9 5.6 52.1 5.1 6.0 14.1 2.7 1 1 2 3 3 3 0 Autophagy protein Apg6 Nnf1 PF03980.9 CAR29831.1 - 1.2e-29 102.4 7.3 2.1e-29 101.6 5.1 1.4 1 0 0 1 1 1 1 Nnf1 Lge1 PF11488.3 CAR29831.1 - 0.015 15.4 3.3 0.015 15.4 2.3 1.9 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 bZIP_1 PF00170.16 CAR29831.1 - 0.022 14.6 2.1 0.022 14.6 1.5 2.0 2 0 0 2 2 2 0 bZIP transcription factor UPF0175 PF03683.8 CAR29831.1 - 0.051 13.0 0.1 0.14 11.6 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) Herpes_BLRF2 PF05812.7 CAR29831.1 - 0.051 13.3 1.5 0.08 12.7 0.3 1.8 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein Ta0938 PF11494.3 CAR29831.1 - 0.12 12.4 0.2 0.29 11.2 0.1 1.7 1 1 0 1 1 1 0 Ta0938 DUF342 PF03961.8 CAR29831.1 - 0.16 10.3 3.9 0.22 9.9 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1664 PF07889.7 CAR29831.1 - 0.23 11.2 1.0 0.63 9.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4618 PF15397.1 CAR29831.1 - 0.34 10.2 9.1 0.066 12.5 1.6 2.5 2 1 2 4 4 4 0 Domain of unknown function (DUF4618) DivIC PF04977.10 CAR29831.1 - 0.49 9.9 3.7 0.38 10.2 1.2 1.8 2 0 0 2 2 2 0 Septum formation initiator DUF1759 PF03564.10 CAR29831.1 - 0.55 10.0 3.1 1.6 8.5 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) LXG PF04740.7 CAR29831.1 - 0.55 9.9 5.5 0.57 9.9 2.0 2.2 2 1 0 2 2 2 0 LXG domain of WXG superfamily Med4 PF10018.4 CAR29831.1 - 0.73 9.2 6.9 1.4 8.3 3.0 2.2 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 TMF_DNA_bd PF12329.3 CAR29831.1 - 1.7 8.5 8.6 0.14 11.9 0.6 2.8 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding YgaB PF14182.1 CAR29831.1 - 2.2 8.6 7.3 3.2 8.0 1.2 2.9 2 1 0 2 2 2 0 YgaB-like protein SlyX PF04102.7 CAR29831.1 - 2.4 8.5 6.7 4.7 7.6 1.1 3.2 3 0 0 3 3 3 0 SlyX CMD PF02627.15 CAR29832.1 - 8.8e-07 28.6 0.0 2.9e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Myotub-related PF06602.9 CAR29833.1 - 1.2e-129 432.1 0.6 1.5e-129 431.8 0.4 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 CAR29833.1 - 0.0028 17.9 0.0 0.0057 16.9 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family GRAM PF02893.15 CAR29833.1 - 0.0046 16.4 0.0 0.013 15.0 0.0 1.7 1 0 0 1 1 1 1 GRAM domain Y_phosphatase PF00102.22 CAR29833.1 - 0.028 13.7 0.0 0.052 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Yippee-Mis18 PF03226.9 CAR29834.1 - 3.1e-16 59.1 4.0 4.6e-16 58.6 2.8 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SNAP PF14938.1 CAR29835.1 - 1.7e-108 362.0 8.7 1.9e-108 361.8 6.0 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP Foie-gras_1 PF11817.3 CAR29835.1 - 3.6e-06 26.6 1.4 3.6e-06 26.6 1.0 1.9 1 1 1 2 2 2 1 Foie gras liver health family 1 TPR_12 PF13424.1 CAR29835.1 - 4e-06 26.6 8.2 0.027 14.3 0.4 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 CAR29835.1 - 0.0013 18.3 3.6 0.075 12.8 0.0 4.3 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 CAR29835.1 - 0.0042 16.8 7.6 5.6 7.1 0.6 5.2 3 3 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 CAR29835.1 - 0.051 13.1 9.2 1.9 8.2 0.1 5.0 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 CAR29835.1 - 0.083 13.3 9.4 22 5.7 0.0 5.4 5 1 0 5 5 5 0 Tetratricopeptide repeat Spatacsin_C PF14649.1 CAR29835.1 - 0.13 11.0 3.0 0.43 9.4 0.4 2.3 1 1 0 2 2 2 0 Spatacsin C-terminus TPR_11 PF13414.1 CAR29835.1 - 0.2 11.2 13.8 0.51 10.0 2.2 4.0 1 1 3 4 4 4 0 TPR repeat TPR_19 PF14559.1 CAR29835.1 - 0.34 11.2 8.6 1.6 9.1 0.4 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 CAR29835.1 - 0.58 10.0 7.0 26 4.9 0.0 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat NSF PF02071.15 CAR29835.1 - 2 9.3 15.8 7.7 7.5 0.2 6.4 7 0 0 7 7 7 0 Aromatic-di-Alanine (AdAR) repeat DUF2225 PF09986.4 CAR29835.1 - 3 7.2 8.8 4.4e+02 0.1 6.1 2.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) CPSase_L_D2 PF02786.12 CAR29836.1 - 7.7e-108 358.6 0.0 4.2e-84 281.0 0.0 2.7 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 CAR29836.1 - 9.1e-38 128.7 0.8 2e-37 127.6 0.5 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 CAR29836.1 - 1.8e-36 125.6 0.4 1.3e-19 70.6 0.0 3.1 3 0 0 3 3 3 2 ATP-grasp domain CPSase_L_chain PF00289.17 CAR29836.1 - 1.7e-35 121.4 0.0 9.9e-17 61.0 0.0 2.6 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 CAR29836.1 - 4.7e-24 84.7 0.0 4.9e-09 35.3 0.0 3.9 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 CAR29836.1 - 2.5e-19 69.2 0.0 4.8e-09 35.7 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CAR29836.1 - 1.1e-15 57.5 0.0 1.3e-06 27.9 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 CAR29836.1 - 5.5e-07 29.2 0.0 0.0057 16.1 0.0 2.7 2 0 0 2 2 2 2 RimK-like ATP-grasp domain Epimerase PF01370.16 CAR29836.1 - 0.00075 19.0 0.0 0.03 13.7 0.0 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family MGS PF02142.17 CAR29836.1 - 0.001 18.9 0.0 0.007 16.2 0.0 2.4 2 0 0 2 2 2 1 MGS-like domain ATP-grasp_5 PF13549.1 CAR29836.1 - 0.045 12.9 0.1 1.8 7.7 0.0 2.7 2 0 0 2 2 2 0 ATP-grasp domain GARS_A PF01071.14 CAR29836.1 - 0.048 13.2 0.0 1.4 8.4 0.0 2.6 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain NAD_binding_5 PF07994.7 CAR29837.1 - 3.4e-114 381.3 0.0 4.2e-114 381.0 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 CAR29837.1 - 1e-43 147.7 0.7 1e-43 147.7 0.5 1.8 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase peroxidase PF00141.18 CAR29838.1 - 1.2e-42 146.0 0.0 1.9e-42 145.3 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Vps35 PF03635.12 CAR29839.1 - 4.7e-276 917.8 27.4 5.4e-276 917.6 19.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 6PF2K PF01591.13 CAR29840.1 - 9.9e-86 286.4 0.3 1.3e-85 286.0 0.2 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CAR29840.1 - 8.2e-30 103.9 0.0 1.7e-29 102.9 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 CAR29840.1 - 5.2e-07 29.6 0.0 1.1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CAR29840.1 - 0.0033 18.2 0.1 0.018 15.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 CAR29840.1 - 0.069 12.3 0.0 0.11 11.6 0.0 1.4 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Peptidase_S64 PF08192.6 CAR29841.1 - 1.8e-241 803.3 0.1 2.1e-241 803.1 0.1 1.0 1 0 0 1 1 1 1 Peptidase family S64 zf-RING_2 PF13639.1 CAR29842.1 - 2.9e-05 23.7 6.0 2.9e-05 23.7 4.2 2.1 2 0 0 2 2 2 1 Ring finger domain PHD PF00628.24 CAR29842.1 - 0.29 10.8 7.9 2.6 7.7 4.5 2.7 2 0 0 2 2 2 0 PHD-finger zf-C3HC4 PF00097.20 CAR29842.1 - 0.57 9.8 7.7 0.48 10.1 3.3 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAR29842.1 - 4.1 7.5 10.1 1.3 9.1 2.9 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PIR PF00399.14 CAR29843.1 - 6e-06 25.4 26.9 1.7e-05 23.9 3.5 3.5 3 0 0 3 3 3 2 Yeast PIR protein repeat PIR PF00399.14 CAR29844.1 - 7.6e-35 117.0 97.8 8.9e-08 31.2 1.8 8.6 8 0 0 8 8 8 7 Yeast PIR protein repeat PIR PF00399.14 CAR29845.1 - 4e-53 175.0 125.7 6.4e-07 28.4 3.8 9.6 9 0 0 9 9 9 9 Yeast PIR protein repeat DUF1989 PF09347.5 CAR29846.1 - 3.9e-53 179.2 0.0 5.3e-53 178.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Ion_trans PF00520.26 CAR29847.1 - 0.034 13.3 0.0 0.042 13.1 0.0 1.1 1 0 0 1 1 1 0 Ion transport protein DnaJ PF00226.26 CAR29848.1 - 3e-20 71.7 1.1 1.2e-19 69.7 0.8 2.1 1 0 0 1 1 1 1 DnaJ domain PigN PF04987.9 CAR29849.1 - 4.4e-132 440.8 41.8 5.7e-132 440.5 29.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 CAR29849.1 - 5.7e-16 58.7 0.3 2.2e-12 46.9 0.2 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 CAR29849.1 - 1.9e-10 40.4 0.0 4.1e-10 39.3 0.0 1.6 1 1 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 CAR29849.1 - 0.0013 18.1 0.1 0.0023 17.3 0.1 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily MFS_1 PF07690.11 CAR29850.1 - 3.8e-17 62.0 17.6 3.8e-17 62.0 12.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 CAR29851.1 - 2e-69 233.6 0.4 3.1e-69 233.0 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR29851.1 - 3.1e-38 131.3 0.0 4.7e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR29851.1 - 0.0014 17.6 0.0 0.0025 16.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CAR29851.1 - 0.084 12.5 0.0 0.31 10.7 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family BAF1_ABF1 PF04684.8 CAR29851.1 - 6.5 5.4 8.9 8.9 5.0 6.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor L51_S25_CI-B8 PF05047.11 CAR29852.1 - 3e-12 46.0 0.1 7.2e-12 44.8 0.1 1.7 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Pkinase PF00069.20 CAR29853.1 - 1.4e-45 155.4 0.0 2.4e-45 154.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR29853.1 - 4.9e-17 61.8 0.0 8.8e-17 61.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Ribosomal_L14 PF00238.14 CAR29854.1 - 3.8e-41 139.6 1.9 4.2e-41 139.5 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Pkinase PF00069.20 CAR29855.1 - 1.4e-41 142.4 0.1 6.3e-27 94.3 0.5 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAR29855.1 - 1.5e-18 66.8 0.0 8.9e-15 54.4 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CAR29855.1 - 0.0091 14.9 0.0 3 6.7 0.0 2.6 3 0 0 3 3 3 2 Kinase-like UcrQ PF02939.11 CAR29856.1 - 5.3e-35 119.0 0.6 6.1e-35 118.9 0.4 1.0 1 0 0 1 1 1 1 UcrQ family polyprenyl_synt PF00348.12 CAR29857.1 - 1.7e-84 282.7 0.0 2e-84 282.4 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Ebp2 PF05890.7 CAR29858.1 - 3.2e-86 288.9 27.2 3.2e-86 288.9 18.9 3.1 1 1 2 3 3 3 1 Eukaryotic rRNA processing protein EBP2 GTP_EFTU PF00009.22 CAR29859.1 - 8.8e-33 113.3 0.0 1.3e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CAR29859.1 - 1e-17 63.8 0.0 1.9e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 CAR29859.1 - 5.2e-16 58.2 0.0 1.1e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CAR29859.1 - 3.5e-09 36.6 0.0 7.3e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 CAR29859.1 - 3e-06 26.9 0.0 9.7e-06 25.3 0.0 2.0 2 0 0 2 2 2 1 Elongation Factor G, domain II Miro PF08477.8 CAR29859.1 - 0.0003 21.2 0.0 0.00072 20.0 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CAR29859.1 - 0.02 14.8 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.5 CAR29859.1 - 0.16 11.1 0.0 0.7 9.0 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AA_permease PF00324.16 CAR29860.1 - 1.1e-72 244.9 37.1 1.4e-72 244.6 25.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CAR29860.1 - 2e-36 125.4 43.5 2.6e-36 125.0 30.2 1.1 1 0 0 1 1 1 1 Amino acid permease MMPL PF03176.10 CAR29860.1 - 4 6.0 8.2 0.2 10.3 0.3 2.5 3 0 0 3 3 3 0 MMPL family Zip PF02535.17 CAR29861.1 - 1.3e-25 90.1 6.5 2.8e-25 88.9 4.5 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter DUF1980 PF09323.5 CAR29861.1 - 0.27 10.9 0.0 0.27 10.9 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1980) CLIP PF12032.3 CAR29861.1 - 0.42 10.7 1.9 1.7 8.7 0.2 2.4 2 1 0 2 2 2 0 Regulatory CLIP domain of proteinases CRAL_TRIO PF00650.15 CAR29862.1 - 0.0043 16.5 0.1 0.39 10.1 0.0 2.4 2 0 0 2 2 2 2 CRAL/TRIO domain SRI PF08236.6 CAR29863.1 - 7.3e-27 93.1 4.4 7.3e-27 93.1 3.1 3.1 2 1 1 3 3 3 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.23 CAR29863.1 - 2.8e-20 73.2 0.1 2.8e-20 73.2 0.1 3.4 2 2 0 2 2 2 1 SET domain WW PF00397.21 CAR29863.1 - 0.035 13.9 0.1 0.074 12.9 0.1 1.5 1 0 0 1 1 1 0 WW domain DUF4410 PF14366.1 CAR29863.1 - 2.9 7.6 7.3 1e+02 2.5 0.0 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4410) STE3 PF02076.10 CAR29865.1 - 2.1e-95 319.0 16.8 2.6e-95 318.7 11.6 1.1 1 0 0 1 1 1 1 Pheromone A receptor Peptidase_M20 PF01546.23 CAR29866.1 - 2.2e-26 92.5 0.0 3.1e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CAR29866.1 - 6.1e-13 48.4 0.0 1.3e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Rep_fac-A_3 PF08661.6 CAR29867.1 - 1.5e-27 95.6 0.0 1.7e-27 95.4 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 2-Hacid_dh_C PF02826.14 CAR29868.1 - 2.4e-40 137.5 0.0 6.3e-40 136.2 0.0 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CAR29868.1 - 1.1e-17 63.7 0.1 1.6e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CAR29868.1 - 0.0052 16.6 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase KRE9 PF05390.6 CAR29869.1 - 1.7e-41 140.8 13.7 3.2e-41 140.0 9.5 1.4 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.4 CAR29869.1 - 1.5e-12 47.7 0.6 1.5e-12 47.7 0.4 2.0 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GBS_Bsp-like PF08481.5 CAR29869.1 - 0.095 12.5 0.6 0.64 9.9 0.0 2.4 1 1 1 2 2 2 0 GBS Bsp-like repeat HECT PF00632.20 CAR29870.1 - 2.7e-89 299.4 0.0 3.7e-89 298.9 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 CAR29870.1 - 3.9e-33 112.9 18.8 6.8e-11 41.8 1.0 3.7 3 0 0 3 3 3 3 WW domain C2 PF00168.25 CAR29870.1 - 1.6e-16 59.8 0.2 4.2e-16 58.5 0.2 1.7 1 0 0 1 1 1 1 C2 domain PUF PF00806.14 CAR29872.1 - 1.7e-55 181.4 31.0 7.9e-08 31.3 1.1 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Ribosomal_S8e PF01201.17 CAR29873.1 - 1.6e-39 135.0 10.0 3.1e-39 134.1 6.9 1.5 1 1 0 1 1 1 1 Ribosomal protein S8e HPD PF05044.7 CAR29873.1 - 0.014 15.0 0.6 0.022 14.4 0.1 1.5 2 0 0 2 2 2 0 Homeo-prospero domain AAA_13 PF13166.1 CAR29873.1 - 0.3 9.4 7.3 0.38 9.1 5.1 1.0 1 0 0 1 1 1 0 AAA domain DUF3959 PF13105.1 CAR29873.1 - 5.4 6.2 10.0 1.1 8.5 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3959) Sas10_Utp3 PF04000.10 CAR29874.1 - 2.5e-12 46.8 1.3 7.8e-12 45.2 0.9 1.9 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Vfa1 PF08432.5 CAR29875.1 - 4e-39 134.5 0.4 4.9e-39 134.2 0.3 1.1 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.9 CAR29875.1 - 5.9 4.7 8.2 8.6 4.2 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.20 CAR29876.1 - 3.8e-50 170.4 0.0 6.4e-50 169.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR29876.1 - 5.6e-24 84.6 0.0 1.7e-23 83.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR29876.1 - 1.9e-05 23.7 0.0 5.6e-05 22.2 0.0 1.7 1 1 0 1 1 1 1 Kinase-like DUF3543 PF12063.3 CAR29877.1 - 1.9e-59 200.7 7.8 2.9e-59 200.1 4.3 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 CAR29877.1 - 1.9e-58 197.6 0.0 7.3e-58 195.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR29877.1 - 2.3e-43 148.1 0.0 3.9e-43 147.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR29877.1 - 0.0042 16.0 0.1 0.05 12.5 0.0 2.4 3 0 0 3 3 3 1 Kinase-like ArfGap PF01412.13 CAR29878.1 - 9.5e-29 99.5 0.0 9.5e-29 99.5 0.0 2.4 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf HSP70 PF00012.15 CAR29878.1 - 0.52 8.1 12.0 0.7 7.7 8.3 1.1 1 0 0 1 1 1 0 Hsp70 protein PAT1 PF09770.4 CAR29878.1 - 0.63 8.2 51.6 0.88 7.7 35.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3306 PF11748.3 CAR29878.1 - 2.7 8.6 13.9 6.4 7.4 9.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) TFIIA PF03153.8 CAR29878.1 - 8 6.2 36.0 12 5.6 24.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mnd1 PF03962.10 CAR29879.1 - 3e-51 173.7 12.9 3.5e-51 173.5 9.0 1.0 1 0 0 1 1 1 1 Mnd1 family Laminin_II PF06009.7 CAR29879.1 - 0.012 15.3 6.3 0.098 12.4 1.5 2.4 1 1 1 2 2 2 0 Laminin Domain II AAA_27 PF13514.1 CAR29879.1 - 0.12 10.0 5.1 0.14 9.7 3.5 1.1 1 0 0 1 1 1 0 AAA domain Tropomyosin_1 PF12718.2 CAR29879.1 - 0.41 10.4 8.7 0.68 9.7 6.0 1.3 1 0 0 1 1 1 0 Tropomyosin like zf-C2H2 PF00096.21 CAR29880.1 - 7.3e-13 48.0 14.8 2.9e-06 27.2 2.5 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CAR29880.1 - 7.3e-08 32.2 17.1 0.00019 21.5 1.2 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CAR29880.1 - 9.3e-05 22.4 18.4 0.0018 18.3 1.3 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 CAR29880.1 - 0.005 17.0 6.1 0.005 17.0 4.2 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.2 CAR29880.1 - 0.0081 16.3 15.9 0.15 12.3 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-BED PF02892.10 CAR29880.1 - 0.026 14.2 12.8 0.21 11.3 2.4 2.9 1 1 1 2 2 2 0 BED zinc finger zf-C2HC_2 PF13913.1 CAR29880.1 - 0.48 10.1 8.5 3.5 7.4 0.4 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-DBF PF07535.7 CAR29880.1 - 1.2 8.8 10.8 1.7 8.4 0.9 3.4 3 0 0 3 3 3 0 DBF zinc finger zf-C2H2_6 PF13912.1 CAR29880.1 - 2.3 8.2 10.4 0.33 10.9 2.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-CHCC PF10276.4 CAR29880.1 - 4.7 7.1 6.3 0.25 11.2 0.2 1.9 2 0 0 2 2 2 0 Zinc-finger domain Cys_Met_Meta_PP PF01053.15 CAR29881.1 - 3.3e-120 400.9 0.0 3.8e-120 400.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.6 CAR29881.1 - 0.0012 17.2 0.0 0.0017 16.7 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase 2-Hacid_dh_C PF02826.14 CAR29882.1 - 3.1e-29 101.3 0.0 4.3e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CAR29882.1 - 0.00015 21.2 0.0 0.00028 20.3 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain COX5B PF01215.14 CAR29883.1 - 1.4e-52 177.0 0.0 1.6e-52 176.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Ribosomal_S26e PF01283.14 CAR29884.1 - 5.1e-50 168.4 9.2 6.1e-50 168.2 6.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF1101 PF06503.6 CAR29884.1 - 0.018 13.8 0.2 0.02 13.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1101) WD40 PF00400.27 CAR29885.1 - 1.9e-17 62.4 2.5 0.00087 19.0 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat COX6A PF02046.10 CAR29886.1 - 6.6e-42 142.0 2.2 7.2e-42 141.9 1.5 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa DUF2741 PF10890.3 CAR29886.1 - 0.018 15.1 0.2 0.028 14.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2741) MT-A70 PF05063.9 CAR29887.1 - 7.9e-55 185.1 0.1 1.4e-54 184.3 0.1 1.4 1 0 0 1 1 1 1 MT-A70 Glyco_hydro_30 PF02055.11 CAR29887.1 - 0.037 12.2 0.0 0.083 11.0 0.0 1.5 1 1 1 2 2 2 0 O-Glycosyl hydrolase family 30 Hist_deacetyl PF00850.14 CAR29888.1 - 5.6e-82 275.5 0.0 7.1e-82 275.1 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Zn_clus PF00172.13 CAR29889.1 - 9.7e-10 38.1 10.6 9.7e-10 38.1 7.3 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 CAR29889.1 - 1.2e-05 24.0 1.4 1.9e-05 23.4 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HEAT_2 PF13646.1 CAR29890.1 - 1.7e-37 127.5 21.3 3.1e-08 33.7 0.0 12.1 8 3 4 13 13 13 8 HEAT repeats DUF3554 PF12074.3 CAR29890.1 - 2.5e-37 129.1 24.4 3.6e-21 75.9 1.7 6.1 6 2 1 7 7 7 2 Domain of unknown function (DUF3554) HEAT_EZ PF13513.1 CAR29890.1 - 1.5e-28 98.4 30.7 0.0069 16.8 0.2 18.0 14 4 5 20 20 20 7 HEAT-like repeat HEAT PF02985.17 CAR29890.1 - 9.8e-28 93.7 16.8 0.0046 16.9 0.0 17.3 20 0 0 20 20 20 6 HEAT repeat CLASP_N PF12348.3 CAR29890.1 - 8.6e-15 54.7 0.0 0.0021 17.4 0.0 7.2 4 1 3 8 8 8 4 CLASP N terminal Vac14_Fab1_bd PF12755.2 CAR29890.1 - 4e-14 52.7 0.1 0.29 11.5 0.0 9.8 8 2 1 10 10 10 3 Vacuolar 14 Fab1-binding region D-ser_dehydrat PF14031.1 CAR29891.1 - 8.6e-22 77.1 0.1 4.3e-21 74.8 0.0 2.2 3 0 0 3 3 3 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 CAR29891.1 - 1.4e-08 34.5 0.0 2e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Kelch_6 PF13964.1 CAR29892.1 - 3.3e-12 45.9 0.7 5e-05 23.2 0.0 5.4 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 CAR29892.1 - 1.7e-11 43.9 0.0 0.0018 18.3 0.0 5.8 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.1 CAR29892.1 - 2.9e-11 42.9 2.5 0.0017 18.0 0.0 5.0 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.20 CAR29892.1 - 1.4e-08 34.1 0.2 0.066 12.7 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 CAR29892.1 - 1.2e-06 28.0 0.5 0.0073 16.0 0.0 4.9 5 0 0 5 5 5 1 Kelch motif Kelch_5 PF13854.1 CAR29892.1 - 0.014 15.3 0.0 0.15 12.0 0.0 2.6 2 0 0 2 2 2 0 Kelch motif Yip1 PF04893.12 CAR29893.1 - 6.8e-09 35.4 8.6 7.6e-09 35.2 6.0 1.2 1 0 0 1 1 1 1 Yip1 domain Metallophos PF00149.23 CAR29894.1 - 2.6e-44 151.0 0.1 3.1e-44 150.7 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EMP24_GP25L PF01105.19 CAR29895.1 - 7e-45 152.9 0.0 8.1e-45 152.7 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PPC PF04151.10 CAR29895.1 - 0.083 13.8 1.4 0.36 11.8 0.1 2.2 2 0 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain DUF946 PF06101.6 CAR29897.1 - 5.7e-07 27.9 2.8 3.4e-06 25.3 1.4 2.1 2 0 0 2 2 2 2 Plant protein of unknown function (DUF946) GCR1_C PF12550.3 CAR29898.1 - 1.8e-17 62.9 0.1 5.2e-17 61.4 0.0 1.9 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Shugoshin_N PF07558.6 CAR29898.1 - 0.021 14.5 0.2 0.046 13.4 0.2 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Phage_int_SAM_4 PF13495.1 CAR29898.1 - 0.036 14.3 0.4 0.12 12.7 0.0 2.2 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain DUF3440 PF11922.3 CAR29898.1 - 0.16 11.4 1.8 0.4 10.2 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3440) MFS_1 PF07690.11 CAR29899.1 - 4.1e-34 117.8 31.2 4.1e-34 117.8 21.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CAR29899.1 - 5.9e-13 48.2 27.6 8.7e-13 47.6 19.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Utp11 PF03998.8 CAR29905.1 - 7.6e-75 251.8 36.8 8.6e-75 251.6 25.5 1.0 1 0 0 1 1 1 1 Utp11 protein Peptidase_A22B PF04258.8 CAR29906.1 - 2.3e-40 138.8 3.7 5.7e-40 137.6 2.6 1.6 1 1 0 1 1 1 1 Signal peptide peptidase RRM_1 PF00076.17 CAR29907.1 - 7.5e-15 54.3 0.0 1.1e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR29907.1 - 5.3e-13 48.7 0.0 8.4e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR29907.1 - 4.4e-08 32.8 0.0 7.2e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 2-Hacid_dh_C PF02826.14 CAR29908.1 - 3e-40 137.2 0.0 1.6e-39 134.8 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CAR29908.1 - 1.4e-17 63.4 0.1 1.8e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CAR29908.1 - 0.042 13.6 0.0 0.093 12.5 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase PI3_PI4_kinase PF00454.22 CAR29909.1 - 4.4e-44 150.7 0.0 1.5e-43 148.9 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 CAR29909.1 - 4.3e-24 84.7 0.0 9.8e-24 83.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) UQ_con PF00179.21 CAR29910.1 - 6e-34 116.4 0.0 7.2e-34 116.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CAR29910.1 - 0.016 14.9 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B PaaB PF06243.6 CAR29911.1 - 0.021 14.9 0.0 0.024 14.7 0.0 1.3 1 1 0 1 1 1 0 Phenylacetic acid degradation B Pam16 PF03656.8 CAR29911.1 - 0.055 13.2 0.1 0.074 12.8 0.1 1.2 1 0 0 1 1 1 0 Pam16 Pyocin_S PF06958.7 CAR29911.1 - 0.087 13.1 0.6 0.12 12.7 0.4 1.1 1 0 0 1 1 1 0 S-type Pyocin TPP_enzyme_N PF02776.13 CAR29912.1 - 1.3e-58 197.3 0.2 5.3e-58 195.3 0.1 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 CAR29912.1 - 4.3e-49 165.9 0.0 5.7e-47 159.1 0.0 2.7 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 CAR29912.1 - 1.1e-34 119.1 0.7 3.1e-34 117.6 0.1 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.14 CAR29912.1 - 0.031 13.7 0.1 0.063 12.7 0.0 1.5 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Myosin_head PF00063.16 CAR29913.1 - 5.1e-223 742.0 3.5 7.1e-223 741.5 2.4 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 CAR29913.1 - 6.1e-47 159.5 0.2 1.2e-46 158.5 0.1 1.5 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 CAR29913.1 - 3.7e-10 39.0 0.0 7.4e-10 38.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CAR29913.1 - 9.3e-07 28.3 0.0 1.9e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CAR29913.1 - 5.8e-05 22.4 0.0 0.00033 20.0 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain AAA_22 PF13401.1 CAR29913.1 - 0.0048 17.0 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CAR29913.1 - 0.012 14.6 1.4 0.047 12.7 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin AAA_19 PF13245.1 CAR29913.1 - 0.036 13.8 0.1 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain Hpr_kinase_C PF07475.7 CAR29913.1 - 0.048 12.9 0.1 4.9 6.4 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_17 PF13207.1 CAR29913.1 - 0.06 14.1 0.0 0.24 12.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 CAR29913.1 - 0.07 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 CAR29913.1 - 0.075 12.6 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 CAR29913.1 - 0.078 12.9 0.0 0.38 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain IQ PF00612.22 CAR29913.1 - 4.8 7.1 10.9 13 5.7 0.6 2.7 1 1 1 2 2 2 0 IQ calmodulin-binding motif She2p PF11435.3 CAR29914.1 - 4.7e-88 293.9 7.1 5.9e-88 293.5 5.0 1.1 1 0 0 1 1 1 1 RNA binding protein She2p GCR1_C PF12550.3 CAR29915.1 - 1.1e-25 89.2 0.2 2.4e-25 88.2 0.1 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes ETX_MTX2 PF03318.8 CAR29915.1 - 0.041 13.4 0.1 0.059 12.9 0.1 1.2 1 0 0 1 1 1 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Med11 PF10280.4 CAR29916.1 - 1.9e-26 92.3 2.7 2.1e-26 92.2 1.8 1.0 1 0 0 1 1 1 1 Mediator complex protein Med29 PF11568.3 CAR29916.1 - 0.017 15.1 0.5 0.025 14.6 0.4 1.3 1 0 0 1 1 1 0 Mediator complex subunit 29 DUF2443 PF10398.4 CAR29916.1 - 0.044 13.5 0.1 0.39 10.5 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2443) DUF4546 PF15079.1 CAR29916.1 - 0.068 12.3 1.3 0.095 11.8 0.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4546) GAS PF13851.1 CAR29916.1 - 0.076 12.1 2.9 0.095 11.8 2.0 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding AAA_32 PF13654.1 CAR29916.1 - 0.082 11.5 0.5 0.093 11.3 0.3 1.0 1 0 0 1 1 1 0 AAA domain Bacillus_HBL PF05791.6 CAR29916.1 - 0.48 9.7 3.6 0.63 9.3 2.5 1.3 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Kinesin-relat_1 PF12711.2 CAR29916.1 - 0.66 10.4 3.9 4.2 7.8 0.3 2.5 2 1 1 3 3 3 0 Kinesin motor Mur_ligase_M PF08245.7 CAR29917.1 - 3.4e-07 30.4 0.0 7.9e-07 29.3 0.0 1.6 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 CAR29917.1 - 0.026 14.5 0.0 0.063 13.3 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain DUF159 PF02586.9 CAR29918.1 - 4.5e-60 202.7 1.4 4.5e-60 202.7 0.9 1.4 2 0 0 2 2 2 1 Uncharacterised ACR, COG2135 TPR_12 PF13424.1 CAR29919.1 - 1.9e-05 24.4 3.1 5.2 7.0 0.0 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 CAR29919.1 - 0.046 13.5 0.5 15 5.7 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_M3 PF01432.15 CAR29920.1 - 1.6e-134 449.3 0.0 2.2e-134 448.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 CAR29920.1 - 0.21 10.9 0.3 0.36 10.1 0.2 1.3 1 0 0 1 1 1 0 Peptidase M50B-like WD40 PF00400.27 CAR29921.1 - 1.4e-53 176.9 9.8 2.2e-08 33.6 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 CAR29921.1 - 4.6e-06 26.4 0.6 0.00053 19.7 0.0 3.0 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CAR29921.1 - 4.4e-05 21.8 8.4 0.03 12.4 0.1 4.2 1 1 3 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CAR29921.1 - 0.01 14.6 0.6 6.3 5.4 0.3 3.2 2 1 1 3 3 3 0 Nup133 N terminal like Gmad2 PF10648.4 CAR29921.1 - 0.03 14.4 0.3 0.77 9.9 0.0 2.5 2 1 0 2 2 2 0 Immunoglobulin-like domain of bacterial spore germination Adaptin_N PF01602.15 CAR29922.1 - 2e-125 419.1 18.0 2.5e-125 418.8 12.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CAR29922.1 - 1.8e-20 73.5 3.7 1.8e-20 73.5 2.6 2.7 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CAR29922.1 - 4.2e-10 39.7 0.4 2.4e-05 24.5 0.0 5.2 4 1 2 6 6 6 2 HEAT repeats HEAT PF02985.17 CAR29922.1 - 2.8e-08 33.1 1.1 0.014 15.3 0.0 5.3 4 0 0 4 4 4 2 HEAT repeat Arm PF00514.18 CAR29922.1 - 0.013 15.3 2.6 0.084 12.7 0.3 3.5 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 CAR29922.1 - 0.041 14.3 1.0 7.6 7.1 0.0 4.0 4 0 0 4 4 4 0 HEAT-like repeat Atx10homo_assoc PF09759.4 CAR29922.1 - 0.1 12.3 1.8 1.5 8.5 0.0 3.4 2 2 1 3 3 3 0 Spinocerebellar ataxia type 10 protein domain Cmc1 PF08583.5 CAR29923.1 - 1.2e-17 63.4 4.6 1.7e-17 62.9 3.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 CAR29923.1 - 0.014 15.3 1.8 0.031 14.2 1.1 1.7 1 1 1 2 2 2 0 CHCH domain COX17 PF05051.8 CAR29923.1 - 1 9.4 4.6 8.6 6.4 0.3 2.4 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) L31 PF09784.4 CAR29924.1 - 1.2e-42 144.1 2.2 1.7e-42 143.6 1.5 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Spc24 PF08286.6 CAR29925.1 - 2.2e-23 82.1 14.7 2.6e-23 81.9 1.2 2.1 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 SUKH-4 PF14435.1 CAR29925.1 - 0.0064 16.2 0.2 0.12 12.0 0.0 2.1 1 1 1 2 2 2 1 SUKH-4 immunity protein DUF2968 PF11180.3 CAR29925.1 - 0.013 14.8 8.7 0.018 14.4 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Allexi_40kDa PF05549.6 CAR29925.1 - 0.014 14.6 3.6 0.019 14.2 2.5 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein TMF_DNA_bd PF12329.3 CAR29925.1 - 0.016 15.0 12.7 0.04 13.7 7.6 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Laminin_II PF06009.7 CAR29925.1 - 0.023 14.4 8.8 0.036 13.8 6.1 1.3 1 0 0 1 1 1 0 Laminin Domain II NPV_P10 PF05531.7 CAR29925.1 - 0.023 14.9 2.4 0.023 14.9 1.6 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Pterin_bind PF00809.17 CAR29925.1 - 0.024 13.9 1.0 0.033 13.5 0.7 1.1 1 0 0 1 1 1 0 Pterin binding enzyme Baculo_PEP_C PF04513.7 CAR29925.1 - 0.043 13.6 4.9 0.38 10.5 1.3 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 CAR29925.1 - 0.054 12.1 9.7 0.078 11.6 6.7 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein GAS PF13851.1 CAR29925.1 - 0.058 12.5 10.2 0.073 12.2 7.1 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 CAR29925.1 - 0.062 12.8 13.9 0.085 12.4 9.6 1.3 1 0 0 1 1 1 0 IncA protein GrpE PF01025.14 CAR29925.1 - 0.25 10.8 7.0 0.37 10.3 4.8 1.2 1 0 0 1 1 1 0 GrpE V_ATPase_I PF01496.14 CAR29925.1 - 0.26 9.0 4.6 0.34 8.7 3.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GLE1 PF07817.8 CAR29925.1 - 0.28 10.1 3.0 0.4 9.5 1.9 1.4 1 1 0 1 1 1 0 GLE1-like protein AAA_13 PF13166.1 CAR29925.1 - 0.42 9.0 9.7 0.92 7.8 6.6 1.4 1 1 0 1 1 1 0 AAA domain DUF2730 PF10805.3 CAR29925.1 - 0.67 9.7 4.1 1.9 8.2 2.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) Phage_GP20 PF06810.6 CAR29925.1 - 0.74 9.2 12.8 2.8 7.3 8.7 1.9 1 1 0 1 1 1 0 Phage minor structural protein GP20 DUF641 PF04859.7 CAR29925.1 - 0.75 9.5 7.0 0.25 11.0 2.0 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) APG6 PF04111.7 CAR29925.1 - 0.9 8.5 8.6 1.1 8.1 6.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 BLOC1_2 PF10046.4 CAR29925.1 - 1 9.5 7.9 3.3 7.9 5.4 2.0 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TBPIP PF07106.8 CAR29925.1 - 1.1 8.8 12.0 3.2 7.2 8.3 1.8 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ACCA PF03255.9 CAR29925.1 - 1.2 8.6 5.5 2.1 7.8 2.5 2.0 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Pox_A_type_inc PF04508.7 CAR29925.1 - 1.4 8.9 5.2 9.9 6.2 0.0 3.6 3 1 1 4 4 3 0 Viral A-type inclusion protein repeat FlaC_arch PF05377.6 CAR29925.1 - 1.5 8.7 6.1 2 8.3 1.2 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Phage_GPO PF05929.6 CAR29925.1 - 1.9 7.6 9.3 6.2 5.9 6.4 1.7 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4407 PF14362.1 CAR29925.1 - 1.9 7.3 8.0 6.1 5.7 5.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TMPIT PF07851.8 CAR29925.1 - 2.1 7.3 4.7 2.7 6.9 3.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein Seryl_tRNA_N PF02403.17 CAR29925.1 - 3.1 7.8 10.4 18 5.3 7.1 2.2 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain PEP-utilisers_N PF05524.8 CAR29925.1 - 3.6 7.3 7.4 3.9 7.2 1.0 2.5 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal OmpH PF03938.9 CAR29925.1 - 4.3 7.2 12.4 6.9 6.5 8.6 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF334 PF03904.8 CAR29925.1 - 8.9 5.5 8.7 16 4.7 5.9 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF334) AAA_23 PF13476.1 CAR29925.1 - 9.4 6.5 14.0 1.5 9.0 7.1 1.6 2 0 0 2 2 2 0 AAA domain DASH_Hsk3 PF08227.6 CAR29926.1 - 6.3e-18 64.7 3.9 8e-18 64.3 2.7 1.1 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like GvpK PF05121.7 CAR29926.1 - 0.06 13.1 0.1 0.075 12.8 0.0 1.1 1 0 0 1 1 1 0 Gas vesicle protein K YebO PF13974.1 CAR29926.1 - 0.09 12.5 0.2 0.095 12.4 0.1 1.1 1 0 0 1 1 1 0 YebO-like protein FlxA PF14282.1 CAR29926.1 - 0.1 12.5 1.1 0.12 12.3 0.7 1.1 1 0 0 1 1 1 0 FlxA-like protein Pkinase PF00069.20 CAR29927.1 - 6.4e-72 241.8 0.4 8.6e-72 241.4 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR29927.1 - 2.7e-35 121.7 0.0 3.9e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR29927.1 - 6.8e-08 31.8 0.0 1.1e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 CAR29927.1 - 0.0062 15.6 0.2 0.042 12.9 0.1 2.1 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CAR29927.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Abhydrolase_1 PF00561.15 CAR29928.1 - 7.8e-27 94.3 0.0 1e-26 93.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.11 CAR29928.1 - 7.6e-22 76.4 0.1 1.6e-21 75.4 0.1 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 CAR29928.1 - 6.3e-07 29.5 0.0 9.7e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CAR29928.1 - 4.3e-05 23.2 0.0 0.0004 20.1 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 CAR29928.1 - 0.00022 20.7 0.0 0.53 9.6 0.0 2.3 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 CAR29928.1 - 0.0041 16.6 0.0 1.1 8.6 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Sdh_cyt PF01127.17 CAR29929.1 - 8.5e-24 83.7 2.3 1.1e-23 83.3 1.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit SH3_1 PF00018.23 CAR29930.1 - 2.3e-14 52.4 0.1 3.5e-14 51.9 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CAR29930.1 - 1.1e-12 47.2 0.1 2e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CAR29930.1 - 4.1e-11 42.1 0.1 5.9e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF2076 PF09849.4 CAR29930.1 - 0.0019 18.3 2.2 0.0023 18.0 1.5 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF2360 PF10152.4 CAR29930.1 - 0.036 14.3 3.2 0.043 14.1 2.2 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Rubella_Capsid PF05750.6 CAR29930.1 - 0.057 12.8 4.1 0.061 12.7 2.9 1.1 1 0 0 1 1 1 0 Rubella capsid protein PAT1 PF09770.4 CAR29930.1 - 0.27 9.4 5.8 0.25 9.5 4.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FlaC_arch PF05377.6 CAR29931.1 - 0.01 15.7 2.2 0.019 14.8 1.5 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DivIC PF04977.10 CAR29931.1 - 0.11 12.0 5.2 0.29 10.6 3.7 1.7 1 1 0 1 1 1 0 Septum formation initiator CAF-1_p150 PF11600.3 CAR29931.1 - 3.9 6.7 18.7 0.23 10.7 9.0 1.8 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Snf7 PF03357.16 CAR29932.1 - 4e-53 179.2 17.8 4e-53 179.2 12.3 1.8 2 0 0 2 2 2 1 Snf7 Snapin_Pallidin PF14712.1 CAR29932.1 - 0.016 15.4 6.4 0.016 15.4 4.4 3.0 2 1 2 4 4 4 0 Snapin/Pallidin CHASE3 PF05227.8 CAR29932.1 - 2.8 7.6 12.1 0.066 12.8 3.2 2.1 2 1 1 3 3 3 0 CHASE3 domain DUF342 PF03961.8 CAR29932.1 - 4.6 5.5 15.9 0.58 8.5 7.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF342) SNARE PF05739.14 CAR29933.1 - 4.8e-18 64.5 3.1 4.8e-18 64.5 2.1 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 CAR29933.1 - 1.1e-17 64.0 4.0 7.1e-17 61.4 0.1 2.9 2 1 0 2 2 2 1 Syntaxin Sed5p PF11416.3 CAR29933.1 - 2.1e-08 33.4 0.6 7.5e-08 31.6 0.1 2.3 2 0 0 2 2 2 1 Integral membrane protein Sed5p Syntaxin-18_N PF10496.4 CAR29933.1 - 0.0028 17.4 2.2 0.0084 15.9 1.5 1.8 1 0 0 1 1 1 1 SNARE-complex protein Syntaxin-18 N-terminus MCPsignal PF00015.16 CAR29933.1 - 0.014 14.9 0.2 0.014 14.9 0.1 2.1 3 1 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin-6_N PF09177.6 CAR29933.1 - 2 8.8 8.1 2.6 8.5 0.0 3.6 3 2 2 5 5 5 0 Syntaxin 6, N-terminal DUF972 PF06156.8 CAR29933.1 - 5.4 7.4 12.2 0.41 11.0 0.7 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF972) Tim54 PF11711.3 CAR29934.1 - 7.2e-132 439.5 2.4 8.4e-132 439.3 1.7 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Peptidase_M27 PF01742.12 CAR29934.1 - 0.0092 14.8 0.3 0.014 14.2 0.2 1.2 1 0 0 1 1 1 1 Clostridial neurotoxin zinc protease Lysine_decarbox PF03641.9 CAR29935.1 - 8.2e-43 145.4 0.1 1.1e-42 145.0 0.1 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase Aldo_ket_red PF00248.16 CAR29936.1 - 3.2e-26 91.8 0.0 4e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family zf-H2C2_2 PF13465.1 CAR29937.1 - 1e-19 69.7 15.5 6.6e-09 35.6 0.2 8.0 8 0 0 8 8 7 4 Zinc-finger double domain zf-C2H2 PF00096.21 CAR29937.1 - 1.1e-12 47.4 20.2 5.7e-06 26.3 0.9 10.5 11 0 0 11 11 9 5 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 CAR29937.1 - 1.1e-07 31.5 26.2 0.00016 21.4 0.2 6.0 4 1 1 5 5 5 3 C2H2-type zinc finger zf-C2H2_4 PF13894.1 CAR29937.1 - 8.6e-07 28.8 14.6 0.00028 20.9 0.5 11.2 11 0 0 11 11 10 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CAR29937.1 - 0.00013 21.9 8.4 0.0018 18.3 0.3 7.3 7 1 1 8 8 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CAR29937.1 - 0.0003 20.8 1.4 0.0003 20.8 1.0 6.9 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 CAR29937.1 - 0.0033 17.0 21.3 0.15 11.7 0.1 5.2 4 0 0 4 4 4 2 zinc-finger of a C2HC-type zf-BED PF02892.10 CAR29937.1 - 0.082 12.6 28.9 0.17 11.6 3.5 5.3 2 1 3 5 5 5 0 BED zinc finger Daxx PF03344.10 CAR29937.1 - 0.22 9.9 21.7 0.32 9.4 15.0 1.2 1 0 0 1 1 1 0 Daxx Family Spt5_N PF11942.3 CAR29937.1 - 0.27 11.8 20.1 0.82 10.3 13.9 1.8 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF2457 PF10446.4 CAR29937.1 - 0.31 9.7 18.3 0.66 8.6 12.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.7 CAR29937.1 - 5.5 6.1 14.9 10 5.2 10.3 1.4 1 0 0 1 1 1 0 SDA1 Methyltransf_16 PF10294.4 CAR29938.1 - 1e-19 70.6 0.0 1.8e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 CAR29938.1 - 3.3e-05 23.5 0.0 8.3e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAR29938.1 - 0.00043 20.0 0.0 0.00085 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR29938.1 - 0.0032 18.0 0.0 0.0091 16.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CAR29938.1 - 0.0068 15.7 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain AF0941-like PF14591.1 CAR29938.1 - 0.017 15.2 0.1 2.2 8.3 0.0 2.5 2 0 0 2 2 2 0 AF0941-like RrnaAD PF00398.15 CAR29938.1 - 0.033 13.2 0.0 0.059 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.7 CAR29938.1 - 0.034 14.6 0.0 0.073 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 CAR29938.1 - 0.085 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 CAR29939.1 - 6.7e-37 127.0 0.0 2e-36 125.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR29939.1 - 4.5e-21 75.0 0.0 2.5e-20 72.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CAR29939.1 - 0.015 14.3 0.2 0.052 12.5 0.1 1.8 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CAR29939.1 - 0.036 13.0 0.0 0.073 12.0 0.0 1.5 1 0 0 1 1 1 0 Kinase-like HbrB PF08539.6 CAR29940.1 - 5.3e-37 127.0 4.4 8e-37 126.5 3.1 1.3 1 0 0 1 1 1 1 HbrB-like CLN3 PF02487.12 CAR29941.1 - 4.7e-136 453.7 16.4 9.1e-135 449.5 11.4 1.9 1 1 0 1 1 1 1 CLN3 protein MFS_1 PF07690.11 CAR29941.1 - 2.3e-08 33.1 15.1 2.3e-05 23.3 2.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PrgI PF12666.2 CAR29941.1 - 0.48 10.6 4.1 0.64 10.2 0.0 3.0 2 1 0 2 2 2 0 PrgI family protein Aminotran_1_2 PF00155.16 CAR29942.1 - 3.2e-81 273.1 0.0 3.8e-81 272.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 CAR29942.1 - 0.00023 20.2 0.0 0.00038 19.6 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 CAR29942.1 - 0.0086 14.4 0.0 0.016 13.5 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 CAR29942.1 - 0.052 12.6 0.0 0.079 12.0 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.14 CAR29942.1 - 0.12 11.1 0.0 0.51 9.0 0.0 1.9 1 1 0 1 1 1 0 Aminotransferase class-V DUF1674 PF07896.7 CAR29943.1 - 5.4e-16 58.5 1.5 1e-15 57.6 1.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Ribosomal_L37 PF08561.5 CAR29945.1 - 2.2e-28 97.6 1.6 2.8e-28 97.3 1.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 Phosphodiest PF01663.17 CAR29946.1 - 9.4e-14 51.4 1.0 2.4e-10 40.3 0.1 2.2 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 CAR29946.1 - 8.2e-05 22.0 0.1 0.00014 21.3 0.1 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 CAR29946.1 - 0.0044 16.2 0.1 0.011 14.9 0.0 1.7 2 0 0 2 2 2 1 Sulfatase MMPL PF03176.10 CAR29946.1 - 1.6 7.3 4.6 2.7 6.6 3.2 1.2 1 0 0 1 1 1 0 MMPL family zf-C2H2_2 PF12756.2 CAR29947.1 - 1.1e-37 128.2 2.7 3.1e-34 117.0 0.4 2.6 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 CAR29947.1 - 0.0039 17.4 6.9 0.44 11.0 0.1 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CAR29947.1 - 0.19 12.1 0.2 0.19 12.1 0.1 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CAR29947.1 - 0.28 11.3 6.2 0.89 9.7 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding AKAP95 PF04988.7 CAR29947.1 - 0.58 9.9 9.3 2.3 7.9 0.2 3.6 3 1 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) adh_short PF00106.20 CAR29948.1 - 1e-20 74.2 0.0 1.6e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CAR29948.1 - 1.3e-12 47.7 0.0 1.7e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 CAR29948.1 - 0.095 11.5 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 CAR29948.1 - 0.18 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Ion_trans_N PF08412.5 CAR29948.1 - 0.18 11.1 0.9 0.31 10.3 0.6 1.4 1 0 0 1 1 1 0 Ion transport protein N-terminal Ribosomal_L17 PF01196.14 CAR29950.1 - 1e-25 90.1 0.0 4.5e-25 88.0 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L17 PALP PF00291.20 CAR29951.1 - 1.5e-56 191.9 0.0 1.7e-56 191.7 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DSPc PF00782.15 CAR29952.1 - 9.8e-26 89.9 0.0 3.4e-21 75.1 0.0 3.4 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CAR29952.1 - 1.5e-05 24.4 0.0 3.7e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 CAR29952.1 - 0.019 14.4 0.1 0.058 12.8 0.0 1.8 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) CBFD_NFYB_HMF PF00808.18 CAR29953.1 - 0.0016 18.4 0.0 0.004 17.1 0.0 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ndufs5 PF10200.4 CAR29953.1 - 0.013 15.4 0.3 0.027 14.4 0.0 1.7 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Cwf_Cwc_15 PF04889.7 CAR29953.1 - 2.9 7.5 25.5 0.035 13.8 10.6 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Paf1 PF03985.8 CAR29955.1 - 1.4e-148 495.3 23.0 1.4e-148 495.3 15.9 2.0 1 1 1 2 2 2 1 Paf1 Esterase PF00756.15 CAR29956.1 - 1.8e-61 207.7 0.2 2.1e-61 207.5 0.1 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 CAR29956.1 - 8.9e-06 25.5 0.0 1.3e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 CAR29956.1 - 0.0052 15.6 0.0 0.0082 15.0 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme PGAP1 PF07819.8 CAR29956.1 - 0.048 13.2 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 CAR29956.1 - 0.072 12.6 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Esterase_phd PF10503.4 CAR29956.1 - 0.14 11.3 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase RCC1_2 PF13540.1 CAR29957.1 - 4.6e-17 61.1 1.8 3.3e-08 32.9 0.6 4.4 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 CAR29957.1 - 1.1e-13 51.1 0.1 0.032 14.4 0.1 6.4 5 2 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Peptidase_M20 PF01546.23 CAR29958.1 - 2.9e-24 85.6 0.0 4.7e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CAR29958.1 - 1.4e-12 47.3 0.0 2.7e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain WD40 PF00400.27 CAR29958.1 - 3.7e-10 39.2 8.2 0.00047 19.9 0.1 6.1 5 1 0 5 5 5 3 WD domain, G-beta repeat WD40 PF00400.27 CAR29959.1 - 4.7e-15 54.8 0.0 9.4e-05 22.1 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat MRP-L27 PF09809.4 CAR29961.1 - 6.6e-31 106.2 1.1 9.3e-31 105.7 0.8 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 SecY PF00344.15 CAR29962.1 - 4.8e-51 173.7 17.0 6.7e-51 173.2 11.8 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 CAR29962.1 - 4.7e-08 32.4 0.5 5.2e-07 29.0 0.0 2.6 2 0 0 2 2 2 1 Plug domain of Sec61p A_deaminase PF00962.17 CAR29963.1 - 1.4e-19 70.2 0.0 1.7e-10 40.3 0.0 3.9 3 1 1 4 4 4 3 Adenosine/AMP deaminase DUF619 PF04768.8 CAR29964.1 - 7.1e-49 165.4 0.0 2e-48 164.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Sld5 PF05916.6 CAR29965.1 - 6.8e-16 58.5 1.7 1e-15 57.9 1.2 1.3 1 0 0 1 1 1 1 GINS complex protein DUF790 PF05626.6 CAR29965.1 - 0.043 12.3 0.0 0.054 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF790) Peptidase_M28 PF04389.12 CAR29967.1 - 3.5e-34 118.0 0.0 5.6e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 CAR29967.1 - 1.6e-10 40.5 0.0 5e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 CAR29967.1 - 0.00015 21.3 0.0 0.00025 20.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 CAR29967.1 - 0.085 11.6 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase DnaJ PF00226.26 CAR29968.1 - 1e-21 76.3 4.2 2.1e-21 75.4 2.9 1.6 1 0 0 1 1 1 1 DnaJ domain DUF4460 PF14687.1 CAR29968.1 - 0.003 17.3 0.2 0.003 17.3 0.1 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4460) GRP PF07172.6 CAR29968.1 - 0.36 11.3 13.1 0.98 9.9 9.1 1.7 1 0 0 1 1 1 0 Glycine rich protein family Mem_trans PF03547.13 CAR29969.1 - 6.1e-63 212.4 7.9 2.6e-62 210.3 5.5 1.7 1 1 0 1 1 1 1 Membrane transport protein SMC_N PF02463.14 CAR29970.1 - 7.8e-51 172.3 62.3 2.9e-50 170.5 43.2 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CAR29970.1 - 2.4e-30 104.9 0.0 1.1e-29 102.8 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 CAR29970.1 - 3.7e-17 63.3 1.5 3.7e-17 63.3 1.1 7.2 2 2 4 6 6 6 1 AAA domain AAA_21 PF13304.1 CAR29970.1 - 7.2e-12 45.8 26.5 2.1e-06 27.9 8.7 4.8 3 2 0 3 3 3 2 AAA domain BLOC1_2 PF10046.4 CAR29970.1 - 0.00019 21.4 3.3 0.00019 21.4 2.3 10.5 6 3 5 12 12 12 3 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_29 PF13555.1 CAR29970.1 - 0.00064 19.1 0.0 0.0018 17.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 CAR29970.1 - 0.31 10.4 4.0 0.73 9.2 0.0 3.1 2 1 0 2 2 2 0 FtsK/SpoIIIE family Cytokin_check_N PF10407.4 CAR29971.1 - 2e-30 104.2 0.6 4.3e-30 103.1 0.4 1.6 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus CAP PF00188.21 CAR29972.1 - 4.3e-20 72.4 1.7 4.3e-20 72.4 1.2 1.8 2 0 0 2 2 2 1 Cysteine-rich secretory protein family KH_1 PF00013.24 CAR29973.1 - 1.1e-78 258.7 29.5 7.8e-13 47.8 0.8 12.3 12 1 0 12 12 12 7 KH domain KH_3 PF13014.1 CAR29973.1 - 4e-49 163.5 21.3 2.9e-08 33.1 0.6 9.9 10 0 0 10 10 10 7 KH domain KH_2 PF07650.12 CAR29973.1 - 7.3e-09 35.0 22.6 0.0049 16.3 0.0 7.0 5 3 1 7 7 7 3 KH domain KH_5 PF13184.1 CAR29973.1 - 9e-07 28.6 17.5 0.13 12.0 0.2 7.2 7 1 0 7 7 7 3 NusA-like KH domain KH_4 PF13083.1 CAR29973.1 - 0.00093 18.7 10.9 0.025 14.2 0.0 6.5 6 1 1 7 7 7 1 KH domain Ras PF00071.17 CAR29974.1 - 1.6e-53 180.4 0.4 1.9e-53 180.1 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR29974.1 - 4.8e-21 75.4 0.1 7.8e-21 74.7 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAR29974.1 - 1e-13 50.9 0.0 1.4e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CAR29974.1 - 2.1e-07 30.3 0.0 2.8e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CAR29974.1 - 8.9e-06 25.2 0.1 1.8e-05 24.2 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CAR29974.1 - 6.2e-05 22.9 0.0 9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.17 CAR29974.1 - 0.034 14.3 0.0 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 RNA helicase ABC1 PF03109.11 CAR29974.1 - 0.079 12.9 0.1 0.35 10.8 0.0 2.1 3 0 0 3 3 3 0 ABC1 family Septin PF00735.13 CAR29974.1 - 0.09 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_16 PF13191.1 CAR29974.1 - 0.1 12.5 0.1 0.15 12.0 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 CAR29974.1 - 0.1 11.7 0.4 0.3 10.2 0.1 1.8 2 1 0 3 3 3 0 Protein of unknown function, DUF258 Mitofilin PF09731.4 CAR29975.1 - 6e-111 371.9 16.3 1.3e-99 334.4 10.0 2.0 1 1 0 2 2 2 2 Mitochondrial inner membrane protein DUF1104 PF06518.6 CAR29975.1 - 0.018 15.1 2.5 0.055 13.6 1.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1104) FliL PF03748.9 CAR29975.1 - 0.087 12.8 2.8 0.44 10.5 1.9 2.3 1 1 0 1 1 1 0 Flagellar basal body-associated protein FliL DUF1664 PF07889.7 CAR29975.1 - 0.12 12.2 1.3 0.34 10.7 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Actin PF00022.14 CAR29976.1 - 7.2e-95 317.7 0.0 6.2e-93 311.3 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CAR29976.1 - 0.028 13.0 0.0 0.15 10.6 0.0 2.0 2 0 0 2 2 2 0 MreB/Mbl protein IBR PF01485.16 CAR29977.1 - 8.5e-17 60.7 43.0 3.4e-09 36.4 2.9 3.9 3 1 0 3 3 3 2 IBR domain zf-C3HC4 PF00097.20 CAR29977.1 - 1e-06 28.2 13.3 1e-06 28.2 9.2 4.9 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CAR29977.1 - 0.00077 19.2 12.0 0.00077 19.2 8.3 4.4 3 1 0 3 3 3 2 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 CAR29977.1 - 0.0038 17.2 12.8 0.0038 17.2 8.9 4.8 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) DUF3189 PF11385.3 CAR29977.1 - 0.093 12.2 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3189) zf-RING_5 PF14634.1 CAR29977.1 - 5.3 6.8 42.0 0.43 10.3 8.0 3.6 3 0 0 3 3 3 0 zinc-RING finger domain DUF3808 PF10300.4 CAR29978.1 - 8e-161 535.7 0.9 9.4e-161 535.4 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_9 PF13371.1 CAR29978.1 - 0.0061 16.3 0.4 0.14 12.0 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat EF-hand_4 PF12763.2 CAR29979.1 - 0.0074 16.0 0.3 0.018 14.7 0.2 1.6 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Vps51 PF08700.6 CAR29980.1 - 7e-12 45.0 4.0 7e-12 45.0 2.8 1.7 2 0 0 2 2 2 1 Vps51/Vps67 HBS1_N PF08938.5 CAR29980.1 - 0.021 14.9 4.7 0.065 13.3 3.2 2.0 1 1 0 1 1 1 0 HBS1 N-terminus SusD-like_3 PF14322.1 CAR29980.1 - 0.11 12.6 1.3 0.12 12.3 0.9 1.1 1 0 0 1 1 1 0 Starch-binding associating with outer membrane Erf4 PF10256.4 CAR29980.1 - 0.26 11.1 1.9 0.29 10.9 1.3 1.3 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family Stn1 PF10451.4 CAR29980.1 - 0.42 9.4 6.7 0.63 8.8 4.3 1.4 1 1 1 2 2 2 0 Telomere regulation protein Stn1 AKNA PF12443.3 CAR29980.1 - 0.8 9.7 6.8 5.9 6.9 0.2 2.4 1 1 1 2 2 2 0 AT-hook-containing transcription factor Med21 PF11221.3 CAR29980.1 - 5.2 7.0 8.8 0.53 10.2 1.1 2.3 1 1 2 3 3 3 0 Subunit 21 of Mediator complex DAO PF01266.19 CAR29981.1 - 3.2e-20 72.3 0.0 5.1e-19 68.3 0.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase SH3_6 PF12913.2 CAR29981.1 - 0.034 13.3 1.3 0.046 12.9 0.1 1.8 2 0 0 2 2 2 0 SH3 domain of the SH3b1 type Pyr_redox PF00070.22 CAR29981.1 - 0.049 14.0 0.1 0.16 12.4 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CAR29981.1 - 0.076 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 CAR29981.1 - 0.14 12.1 0.1 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.1 CAR29981.1 - 0.14 12.3 0.0 0.34 11.1 0.0 1.6 2 0 0 2 2 2 0 Putative NAD(P)-binding EF-hand_7 PF13499.1 CAR29982.1 - 1.5e-10 41.0 0.2 9e-08 32.1 0.1 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CAR29982.1 - 5.4e-08 31.5 4.1 0.00027 20.0 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 CAR29982.1 - 2.2e-07 30.1 1.8 0.00076 19.1 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 CAR29982.1 - 3.9e-07 29.5 1.5 4e-05 23.1 0.2 3.3 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_9 PF14658.1 CAR29982.1 - 4.2e-07 29.7 0.0 0.0034 17.2 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain UPF0154 PF03672.8 CAR29982.1 - 0.00088 18.8 0.0 0.011 15.3 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) EF-hand_4 PF12763.2 CAR29982.1 - 0.065 12.9 0.1 0.16 11.7 0.1 1.6 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand FDX-ACB PF03147.9 CAR29982.1 - 0.12 12.5 0.1 0.26 11.4 0.1 1.6 1 1 0 1 1 1 0 Ferredoxin-fold anticodon binding domain PAS PF00989.19 CAR29983.1 - 1.6e-17 63.2 0.0 8e-17 61.0 0.0 2.1 2 0 0 2 2 2 1 PAS fold Zn_clus PF00172.13 CAR29983.1 - 2.8e-06 27.1 8.4 5e-06 26.3 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CpeT PF06206.6 CAR29983.1 - 0.062 12.9 0.1 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 CpeT/CpcT family (DUF1001) Toxin-deaminase PF14424.1 CAR29983.1 - 0.075 13.0 0.1 0.87 9.5 0.0 2.3 2 0 0 2 2 2 0 The BURPS668_1122 family of deaminases PAS_4 PF08448.5 CAR29983.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 PAS fold tRNA_bind PF01588.15 CAR29984.1 - 2.3e-29 101.0 0.4 3.9e-29 100.3 0.3 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 CAR29984.1 - 0.0096 16.3 0.5 0.033 14.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Suf PF05843.9 CAR29984.1 - 0.55 9.9 6.2 1.1 8.8 4.3 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TP53IP5 PF15331.1 CAR29984.1 - 0.65 9.8 9.5 1.5 8.7 6.6 1.5 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DUF236 PF03057.9 CAR29984.1 - 0.89 9.5 14.5 0.39 10.6 6.4 2.2 2 0 0 2 2 2 0 Protein of unknown function Zn_clus PF00172.13 CAR29985.1 - 2.8e-09 36.7 12.9 7.7e-09 35.3 9.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 CAR29986.1 - 3.3e-98 329.2 19.2 4e-98 328.9 13.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR29986.1 - 7.7e-28 97.2 37.0 4.2e-22 78.3 8.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CAR29986.1 - 6.6e-07 27.9 3.6 6.6e-07 27.9 2.5 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Ribosomal_L18e PF00828.14 CAR29987.1 - 8.8e-33 113.4 0.3 1.1e-32 113.0 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 HD_3 PF13023.1 CAR29988.1 - 8.5e-37 126.4 2.0 1.1e-36 126.0 1.4 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 CAR29988.1 - 1.3e-05 25.2 0.2 2.3e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 HD domain Glycos_transf_4 PF00953.16 CAR29989.1 - 4e-29 101.4 11.1 4e-29 101.4 7.7 2.2 2 1 0 2 2 2 1 Glycosyl transferase family 4 WD40 PF00400.27 CAR29990.1 - 6.7e-38 127.2 20.5 6.6e-09 35.3 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat GSHPx PF00255.14 CAR29991.1 - 6.8e-45 150.8 0.1 9.3e-45 150.4 0.1 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 CAR29991.1 - 1.3e-05 24.8 0.1 5.3e-05 22.8 0.1 1.9 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CAR29991.1 - 3.4e-05 23.4 0.0 0.00015 21.2 0.0 1.9 1 1 0 1 1 1 1 Redoxin SCO1-SenC PF02630.9 CAR29991.1 - 0.033 13.8 0.0 0.25 10.9 0.0 2.1 1 1 0 1 1 1 0 SCO1/SenC SNF2_N PF00176.18 CAR29992.1 - 1.5e-79 266.9 0.3 2.6e-79 266.1 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 CAR29992.1 - 3.6e-40 136.3 1.7 3.6e-40 136.3 1.2 2.5 3 0 0 3 3 3 1 SLIDE HAND PF09110.6 CAR29992.1 - 6.5e-32 110.2 3.0 6.5e-32 110.2 2.1 4.1 5 0 0 5 5 5 1 HAND Helicase_C PF00271.26 CAR29992.1 - 3.9e-15 55.4 0.0 2.4e-14 52.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAR29992.1 - 1.4e-07 31.5 0.0 1.4e-07 31.5 0.0 4.9 4 2 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CAR29992.1 - 6.5e-05 22.4 0.0 0.00016 21.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 CAR29992.1 - 0.0066 15.8 0.1 0.019 14.3 0.1 1.7 1 0 0 1 1 1 1 DEAD_2 AAA_14 PF13173.1 CAR29992.1 - 0.011 15.5 0.1 0.069 13.0 0.0 2.4 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 CAR29993.1 - 6.2e-07 29.0 7.0 1.6 8.7 0.7 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat MMR_HSR1 PF01926.18 CAR29994.1 - 6.1e-16 58.4 0.2 3.1e-14 52.9 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CAR29994.1 - 1.8e-07 30.5 0.2 2.5e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF258 PF03193.11 CAR29994.1 - 0.00073 18.7 0.1 0.002 17.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 CAR29994.1 - 0.009 15.1 0.1 0.018 14.1 0.1 1.5 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 CAR29994.1 - 0.043 14.3 0.2 0.19 12.2 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 CAR29994.1 - 0.054 13.3 7.0 0.06 13.1 0.6 3.2 3 1 0 3 3 3 0 Dynamin family DUF840 PF05801.6 CAR29994.1 - 0.076 13.1 0.4 0.19 11.8 0.2 1.6 1 0 0 1 1 1 0 Lagovirus protein of unknown function (DUF840) Use1 PF09753.4 CAR29995.1 - 9.9e-06 25.1 0.1 1.4e-05 24.7 0.0 1.3 1 1 0 1 1 1 1 Membrane fusion protein Use1 GvpG PF05120.7 CAR29995.1 - 0.26 11.1 2.7 0.82 9.5 0.0 2.6 3 0 0 3 3 3 0 Gas vesicle protein G MFS_1 PF07690.11 CAR29996.1 - 2.7e-31 108.5 32.2 2.7e-31 108.5 22.3 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CAR29996.1 - 4.5e-13 48.5 4.5 4.5e-13 48.5 3.1 3.6 1 1 1 4 4 4 1 Sugar (and other) transporter Selenoprotein_S PF06936.6 CAR29996.1 - 0.025 14.1 0.2 0.053 13.0 0.0 1.7 2 0 0 2 2 2 0 Selenoprotein S (SelS) SecE PF00584.15 CAR29996.1 - 0.084 12.4 0.0 0.084 12.4 0.0 3.4 3 0 0 3 3 3 0 SecE/Sec61-gamma subunits of protein translocation complex MFS_1 PF07690.11 CAR29997.1 - 3.5e-30 104.9 33.6 3.5e-30 104.9 23.3 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CAR29997.1 - 1.1e-10 40.7 6.3 1.1e-10 40.7 4.3 3.5 1 1 3 4 4 4 2 Sugar (and other) transporter Bystin PF05291.6 CAR29998.1 - 2.8e-120 400.8 0.0 5.4e-120 399.9 0.0 1.4 1 1 0 1 1 1 1 Bystin MRP-S28 PF10213.4 CAR29999.1 - 0.038 14.0 0.4 0.05 13.6 0.3 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit protein Serine_rich PF08824.5 CAR29999.1 - 0.093 12.4 2.0 0.16 11.6 1.4 1.4 1 1 0 1 1 1 0 Serine rich protein interaction domain RCC1 PF00415.13 CAR30000.1 - 5.1e-62 205.9 0.4 3.9e-12 46.1 0.1 7.8 7 2 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CAR30000.1 - 2.7e-33 112.8 19.8 1.8e-08 33.7 0.0 7.2 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat His_biosynth PF00977.16 CAR30001.1 - 1.4e-45 155.3 0.2 6.4e-45 153.2 0.2 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 CAR30001.1 - 7.6e-28 97.2 0.0 1.3e-27 96.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 CAR30001.1 - 4.6e-09 36.1 0.0 0.00015 21.4 0.0 2.2 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 CAR30001.1 - 1.9e-07 30.8 0.0 7e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 CAR30001.1 - 0.0012 18.3 0.1 0.45 9.9 0.0 2.3 2 0 0 2 2 2 2 Peptidase C26 DAHP_synth_1 PF00793.15 CAR30002.1 - 1.1e-101 339.0 0.0 1.4e-101 338.7 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Arrestin_C PF02752.17 CAR30003.1 - 0.00024 21.2 2.5 0.00027 21.0 0.0 2.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Homeobox_KN PF05920.6 CAR30004.1 - 2.6e-17 62.2 0.3 5.3e-17 61.2 0.2 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 CAR30004.1 - 6.9e-06 25.5 0.3 1.8e-05 24.2 0.1 1.8 2 0 0 2 2 2 1 Homeobox domain HTH_32 PF13565.1 CAR30004.1 - 0.53 11.1 3.2 16 6.3 0.3 2.7 2 1 0 2 2 2 0 Homeodomain-like domain zf-CCHC PF00098.18 CAR30006.1 - 3.6e-07 29.8 3.2 3.6e-07 29.8 2.2 1.6 2 0 0 2 2 2 1 Zinc knuckle Retrotrans_gag PF03732.12 CAR30006.1 - 0.011 15.7 0.4 0.021 14.8 0.3 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC_5 PF14787.1 CAR30006.1 - 0.034 13.6 3.7 0.066 12.7 2.5 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.1 CAR30006.1 - 0.041 13.5 1.7 0.1 12.3 1.2 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.1 CAR30006.1 - 3.1 7.6 7.4 0.4 10.4 2.3 1.6 2 0 0 2 2 2 0 Zinc knuckle Aconitase PF00330.15 CAR30007.1 - 1.1e-178 594.5 0.0 1.9e-178 593.7 0.0 1.4 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CAR30007.1 - 1.7e-47 160.7 0.0 3.3e-47 159.8 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain ABC_membrane PF00664.18 CAR30008.1 - 3.1e-54 184.2 38.6 7.3e-35 120.7 6.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CAR30008.1 - 4.4e-47 159.8 0.0 4.1e-28 98.3 0.1 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CAR30008.1 - 2.8e-10 39.7 8.9 0.048 12.8 0.0 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CAR30008.1 - 1.4e-08 34.9 0.0 0.0097 15.9 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 CAR30008.1 - 7.8e-07 29.3 18.8 0.0072 16.3 0.0 6.1 5 2 0 5 5 3 2 AAA domain AAA_29 PF13555.1 CAR30008.1 - 2.6e-06 26.8 0.3 0.0085 15.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 CAR30008.1 - 4.6e-06 26.5 0.2 0.029 14.3 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 CAR30008.1 - 5.6e-05 23.2 1.4 0.053 13.6 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 CAR30008.1 - 0.0004 19.9 2.0 0.094 12.1 0.0 3.1 3 1 1 4 4 4 1 AAA-like domain AAA_25 PF13481.1 CAR30008.1 - 0.00074 18.9 0.2 0.9 8.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CAR30008.1 - 0.001 19.8 0.0 3.1 8.6 0.0 3.1 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 CAR30008.1 - 0.0015 19.0 0.4 3 8.3 0.0 3.1 2 0 0 2 2 2 1 Miro-like protein T2SE PF00437.15 CAR30008.1 - 0.0025 16.7 0.0 1.2 7.9 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF258 PF03193.11 CAR30008.1 - 0.0025 17.0 0.2 0.39 9.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CAR30008.1 - 0.0051 16.6 4.8 0.091 12.5 0.0 3.4 3 0 0 3 3 3 1 Dynamin family ABC_ATPase PF09818.4 CAR30008.1 - 0.0052 15.4 2.1 1 7.8 0.0 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class Zeta_toxin PF06414.7 CAR30008.1 - 0.0058 15.7 0.2 1.1 8.3 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.1 CAR30008.1 - 0.0062 16.1 0.8 2.2 7.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 CAR30008.1 - 0.0074 15.7 0.0 0.27 10.7 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_23 PF13476.1 CAR30008.1 - 0.012 15.9 7.2 1.8 8.8 4.6 3.2 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.12 CAR30008.1 - 0.013 15.2 5.9 2.1 8.1 0.1 4.0 4 0 0 4 4 4 0 Domain of unknown function DUF87 AAA_18 PF13238.1 CAR30008.1 - 0.02 15.2 0.0 13 6.1 0.0 3.1 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 CAR30008.1 - 0.02 14.5 0.7 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 CAR30008.1 - 0.049 13.5 0.4 1.4 8.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.17 CAR30008.1 - 0.064 12.1 2.5 8.9 5.0 0.0 3.7 4 0 0 4 4 4 0 NB-ARC domain NACHT PF05729.7 CAR30008.1 - 0.066 12.8 1.2 0.3 10.7 0.0 2.6 3 0 0 3 3 2 0 NACHT domain cobW PF02492.14 CAR30008.1 - 1.1 8.7 6.1 0.27 10.6 0.1 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Cys_Met_Meta_PP PF01053.15 CAR30009.1 - 3.6e-146 486.3 0.0 4.1e-146 486.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 CAR30009.1 - 2e-14 53.4 0.1 2e-13 50.1 0.1 2.1 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 CAR30009.1 - 6.7e-12 45.0 0.0 1e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 CAR30009.1 - 3.5e-08 32.5 0.1 5.1e-08 32.0 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CAR30009.1 - 6.9e-05 22.1 0.0 0.00014 21.1 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 CAR30009.1 - 7.2e-05 21.2 0.1 0.00011 20.6 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase SLA_LP_auto_ag PF05889.8 CAR30009.1 - 0.03 12.8 0.0 0.042 12.3 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) GDC-P PF02347.11 CAR30009.1 - 0.045 12.4 0.0 0.066 11.9 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein CPSase_L_D2 PF02786.12 CAR30009.1 - 0.081 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Gtr1_RagA PF04670.7 CAR30010.1 - 3.4e-66 222.7 0.6 4.4e-66 222.3 0.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 CAR30010.1 - 0.00039 19.7 0.1 0.0014 17.8 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family SRPRB PF09439.5 CAR30010.1 - 0.017 14.3 0.1 0.038 13.1 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 CAR30010.1 - 0.031 14.1 0.0 0.072 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain GTP_cyclohydro2 PF00925.15 CAR30010.1 - 0.048 12.8 0.0 0.079 12.2 0.0 1.3 1 0 0 1 1 1 0 GTP cyclohydrolase II TYW3 PF02676.9 CAR30011.1 - 8e-67 224.3 0.0 8.9e-67 224.1 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase TYW3 MIF4G PF02854.14 CAR30012.1 - 7e-49 166.0 0.3 1.3e-48 165.1 0.2 1.5 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 CAR30012.1 - 1.5e-26 92.0 0.5 1.5e-26 92.0 0.3 2.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4G1 AAA PF00004.24 CAR30013.1 - 3.5e-43 146.9 0.0 6.5e-43 146.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CAR30013.1 - 4e-07 29.8 0.0 1.5e-06 27.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CAR30013.1 - 5.6e-07 29.6 0.0 1.2e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CAR30013.1 - 6.6e-06 26.2 0.1 0.00036 20.6 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CAR30013.1 - 2.5e-05 24.3 0.0 6.3e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 CAR30013.1 - 3e-05 24.8 0.2 0.00012 22.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CAR30013.1 - 0.00013 21.1 0.0 0.00023 20.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CAR30013.1 - 0.00018 21.2 0.1 0.0004 20.0 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 CAR30013.1 - 0.00019 20.8 0.0 0.00035 20.0 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 CAR30013.1 - 0.00057 19.7 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CAR30013.1 - 0.0017 18.2 0.0 0.0039 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CAR30013.1 - 0.0018 18.2 0.0 0.0036 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CAR30013.1 - 0.0043 16.1 0.0 0.011 14.8 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin DUF2072 PF09845.4 CAR30013.1 - 0.0044 16.9 1.7 0.011 15.6 1.2 1.7 1 0 0 1 1 1 1 Zn-ribbon containing protein (DUF2072) AAA_3 PF07726.6 CAR30013.1 - 0.0049 16.4 0.0 0.014 14.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 CAR30013.1 - 0.0052 17.0 2.3 0.024 14.9 0.0 2.9 3 1 0 3 3 3 1 AAA domain TIP49 PF06068.8 CAR30013.1 - 0.011 14.5 0.0 0.026 13.2 0.0 1.6 1 0 0 1 1 1 0 TIP49 C-terminus PhoH PF02562.11 CAR30013.1 - 0.013 14.7 0.0 0.046 12.9 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.16 CAR30013.1 - 0.016 14.4 0.0 0.036 13.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CAR30013.1 - 0.029 13.8 0.1 0.14 11.6 0.0 2.1 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 CAR30013.1 - 0.031 13.8 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CAR30013.1 - 0.032 13.6 0.1 0.12 11.7 0.0 1.8 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.17 CAR30013.1 - 0.034 14.3 0.0 0.073 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF815 PF05673.8 CAR30013.1 - 0.042 12.7 0.0 0.098 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.7 CAR30013.1 - 0.055 13.1 0.0 0.35 10.4 0.0 2.0 1 1 1 2 2 2 0 NACHT domain NB-ARC PF00931.17 CAR30013.1 - 0.062 12.1 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 CAR30013.1 - 0.078 11.8 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Tropomyosin PF00261.15 CAR30013.1 - 0.15 11.1 2.6 0.22 10.5 0.4 2.0 2 0 0 2 2 2 0 Tropomyosin Glyco_tran_28_C PF04101.11 CAR30014.1 - 2.1e-29 102.3 0.0 8.1e-29 100.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 CAR30014.1 - 0.00067 18.9 0.0 0.00076 18.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 1 HSP20 PF00011.16 CAR30015.1 - 1.7e-17 63.1 0.4 3.1e-17 62.3 0.1 1.6 2 0 0 2 2 2 1 Hsp20/alpha crystallin family Bac_luciferase PF00296.15 CAR30016.1 - 7e-50 169.8 0.0 1e-49 169.3 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase FAD_binding_7 PF03441.9 CAR30017.1 - 1.3e-82 277.0 0.1 1.8e-82 276.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 CAR30017.1 - 4.7e-28 98.0 0.0 8.5e-28 97.1 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase adh_short_C2 PF13561.1 CAR30018.1 - 1.1e-24 87.5 0.0 1.4e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CAR30018.1 - 3.6e-24 85.5 0.0 1.9e-23 83.2 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CAR30018.1 - 1e-10 41.5 0.0 5.5e-10 39.1 0.0 1.9 2 0 0 2 2 2 1 KR domain 3Beta_HSD PF01073.14 CAR30018.1 - 7.2e-06 24.8 0.2 1.6e-05 23.7 0.1 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CAR30018.1 - 3.3e-05 23.4 1.4 7.2e-05 22.3 0.2 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CAR30018.1 - 0.036 12.9 0.0 0.058 12.2 0.0 1.4 1 1 0 1 1 1 0 RmlD substrate binding domain DHquinase_II PF01220.14 CAR30018.1 - 0.067 12.5 0.1 0.14 11.4 0.0 1.5 1 1 0 1 1 1 0 Dehydroquinase class II Catalase PF00199.14 CAR30019.1 - 3.1e-157 523.1 0.0 4.2e-157 522.7 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 CAR30019.1 - 1.8e-11 43.7 0.0 6.8e-11 41.8 0.0 2.0 2 0 0 2 2 2 1 Catalase-related immune-responsive OPT PF03169.10 CAR30020.1 - 4e-123 412.0 49.7 4.6e-123 411.8 34.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Epimerase PF01370.16 CAR30021.1 - 4.2e-21 75.4 0.0 6.6e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CAR30021.1 - 7e-12 44.6 0.0 1e-11 44.0 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CAR30021.1 - 6.7e-11 42.5 0.0 1.6e-10 41.3 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 CAR30021.1 - 3.6e-10 39.2 0.0 2.6e-09 36.3 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 CAR30021.1 - 5.5e-07 28.7 0.0 8.6e-07 28.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 CAR30021.1 - 5.6e-06 26.3 0.0 8.9e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 CAR30021.1 - 0.00014 20.8 0.0 0.0002 20.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 CAR30021.1 - 0.0017 17.6 0.1 0.012 14.8 0.0 2.2 3 0 0 3 3 3 1 NmrA-like family adh_short_C2 PF13561.1 CAR30021.1 - 0.0043 16.8 0.0 0.0068 16.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CAR30021.1 - 0.011 15.4 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 0 KR domain Shikimate_DH PF01488.15 CAR30021.1 - 0.028 14.5 0.0 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.15 CAR30021.1 - 0.048 13.5 0.2 0.16 11.9 0.0 2.0 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.12 CAR30021.1 - 0.074 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent RTA1 PF04479.8 CAR30022.1 - 1.2e-72 244.1 11.9 1.2e-72 244.1 8.3 2.0 2 0 0 2 2 2 1 RTA1 like protein DUF4257 PF14074.1 CAR30022.1 - 0.027 14.1 1.0 0.069 12.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4257) GNVR PF13807.1 CAR30022.1 - 2.7 7.7 5.8 11 5.8 0.2 3.2 3 0 0 3 3 3 0 G-rich domain on putative tyrosine kinase Fungal_trans PF04082.13 CAR30023.1 - 9.5e-20 70.5 0.9 9.5e-20 70.5 0.6 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR30023.1 - 1.1e-09 38.0 8.2 2.8e-09 36.7 5.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SnoaL_4 PF13577.1 CAR30024.1 - 1e-18 67.4 0.0 1.1e-18 67.3 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 CAR30024.1 - 0.0083 16.3 0.0 0.0099 16.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) LBP_BPI_CETP PF01273.20 CAR30024.1 - 0.015 14.6 0.3 3.4 7.0 0.1 2.1 2 0 0 2 2 2 0 LBP / BPI / CETP family, N-terminal domain VERL PF11386.3 CAR30024.1 - 0.043 13.7 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 Vitelline envelope receptor for lysin Lumazine_bd_2 PF12893.2 CAR30024.1 - 0.048 14.1 0.0 0.091 13.3 0.0 1.5 1 1 0 1 1 1 0 Putative lumazine-binding DUP PF00674.13 CAR30703.1 - 9.9e-27 93.0 3.8 8.8e-14 51.3 0.1 2.2 2 0 0 2 2 2 2 DUP family Aminotran_3 PF00202.16 CAR30704.1 - 2.3e-83 279.8 0.0 7.1e-83 278.2 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 CAR30704.1 - 0.00047 19.4 0.0 0.0011 18.2 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase AAA_26 PF13500.1 CAR30705.1 - 1.5e-40 138.9 0.0 1.8e-40 138.6 0.0 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 CAR30705.1 - 0.079 12.3 0.1 2.3 7.6 0.0 2.3 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUP PF00674.13 CAR30706.1 - 1.5e-06 28.0 0.7 1.5e-06 28.0 0.5 2.5 2 1 1 3 3 3 1 DUP family Spore_SspJ PF09575.5 CAR30706.1 - 0.078 13.1 0.7 0.26 11.5 0.0 2.0 2 0 0 2 2 2 0 Small spore protein J (Spore_SspJ) DUF4648 PF15505.1 CAR30707.1 - 0.037 14.2 1.0 0.046 13.9 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4648) DUF3561 PF12084.3 CAR30707.1 - 0.19 11.5 3.9 4.1 7.3 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3561) DUP PF00674.13 CAR30708.1 - 1.1e-25 89.6 13.7 1e-14 54.3 0.1 3.0 2 2 0 2 2 2 2 DUP family SPC12 PF06645.8 CAR30708.1 - 4.1 7.2 7.1 0.68 9.7 0.3 2.3 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DIOX_N PF14226.1 CAR30709.1 - 4.5e-31 107.7 0.1 3.7e-30 104.8 0.0 2.2 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CAR30709.1 - 6e-15 55.3 0.0 1.1e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Aa_trans PF01490.13 CAR30710.1 - 1.4e-28 99.5 41.6 1.8e-28 99.2 28.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUP PF00674.13 CAR30711.1 - 1.7e-25 89.0 0.1 1e-14 54.3 0.0 2.3 2 0 0 2 2 2 2 DUP family FMN_bind_2 PF04299.7 CAR30712.1 - 5.9e-55 185.3 0.0 7.1e-55 185.0 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain Nuc_N PF14448.1 CAR30712.1 - 0.11 12.1 0.0 0.38 10.3 0.0 1.9 2 0 0 2 2 2 0 Nuclease N terminal DUF4146 PF13652.1 CAR30712.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4146) Aminotran_3 PF00202.16 CAR30713.1 - 2.8e-90 302.5 0.0 3.3e-90 302.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Peptidase_M16 PF00675.15 CAR30714.1 - 5.2e-21 74.9 0.0 8.6e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CAR30714.1 - 1e-08 35.0 0.1 3.5e-08 33.3 0.0 1.9 2 1 0 2 2 2 1 Peptidase M16 inactive domain EcoR124_C PF12008.3 CAR30714.1 - 0.03 13.5 0.0 0.048 12.8 0.0 1.2 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal DUF2414 PF10309.4 CAR30714.1 - 0.15 11.7 0.3 0.43 10.2 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2414) UPF0193 PF05250.6 CAR30714.1 - 0.18 11.3 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0193) Mt_ATP-synt_D PF05873.7 CAR30715.1 - 6.5e-15 55.1 2.5 8.7e-15 54.7 1.7 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) IFT57 PF10498.4 CAR30715.1 - 0.0022 16.8 1.2 0.0026 16.5 0.9 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 EzrA PF06160.7 CAR30715.1 - 0.014 13.5 2.8 0.037 12.2 1.2 1.7 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Pox_F11 PF04943.7 CAR30715.1 - 0.053 12.3 0.1 0.059 12.2 0.1 1.1 1 0 0 1 1 1 0 Poxvirus F11 protein LTXXQ PF07813.7 CAR30715.1 - 0.06 13.8 0.7 1.1 9.7 0.3 2.1 1 1 1 2 2 2 0 LTXXQ motif family protein DUF2408 PF10303.4 CAR30715.1 - 0.13 12.3 1.1 0.21 11.7 0.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Cauli_AT PF03233.8 CAR30715.1 - 0.13 11.9 2.1 0.23 11.1 1.4 1.6 1 1 0 1 1 1 0 Aphid transmission protein Fungal_trans PF04082.13 CAR30716.1 - 9e-23 80.4 0.0 1.8e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR30716.1 - 8.1e-08 32.0 8.4 1.4e-07 31.2 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Npa1 PF11707.3 CAR30717.1 - 2.4e-91 306.1 6.4 9.4e-91 304.2 4.5 2.1 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal MSC PF09402.5 CAR30718.1 - 0.27 9.9 4.9 0.29 9.8 2.8 1.3 1 1 0 1 1 1 0 Man1-Src1p-C-terminal domain RE_Alw26IDE PF09665.5 CAR30718.1 - 0.31 9.7 5.6 0.36 9.4 3.9 1.1 1 0 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) Fungal_trans PF04082.13 CAR30719.1 - 1.2e-25 89.8 1.7 3.5e-25 88.3 1.2 1.9 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR30719.1 - 9.7e-05 22.2 7.1 9.7e-05 22.2 4.9 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ARPC4 PF05856.7 CAR30720.1 - 5.4e-72 240.7 4.5 6e-72 240.5 3.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) FF PF01846.14 CAR30721.1 - 7.2e-35 118.7 21.1 2e-13 50.0 0.0 6.1 6 0 0 6 6 6 4 FF domain WW PF00397.21 CAR30721.1 - 1.4e-19 69.5 9.7 1e-10 41.2 0.4 2.8 3 0 0 3 3 3 2 WW domain PQQ PF01011.16 CAR30721.1 - 0.0023 17.3 0.2 0.031 13.8 0.0 2.3 2 0 0 2 2 2 1 PQQ enzyme repeat RBD-FIP PF09457.5 CAR30721.1 - 0.014 15.1 1.8 0.071 12.9 1.3 2.3 1 0 0 1 1 1 0 FIP domain PsbP PF01789.11 CAR30721.1 - 0.018 14.4 1.4 0.39 10.1 1.0 2.4 1 1 0 1 1 1 0 PsbP PQQ_2 PF13360.1 CAR30721.1 - 0.1 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 PQQ-like domain G-gamma PF00631.17 CAR30721.1 - 0.14 11.9 3.6 0.29 10.8 0.9 2.7 2 0 0 2 2 2 0 GGL domain Peptidase_S24 PF00717.18 CAR30722.1 - 1.4e-07 30.9 0.0 2.4e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like DUF371 PF04027.8 CAR30722.1 - 0.044 13.4 0.0 0.062 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF371) HAS-barrel PF09378.5 CAR30722.1 - 0.083 12.8 0.1 0.16 11.9 0.1 1.5 1 1 0 1 1 1 0 HAS barrel domain Ydc2-catalyt PF09159.5 CAR30723.1 - 6.9e-53 179.9 0.1 1.1e-52 179.2 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.8 CAR30723.1 - 0.0075 16.1 0.7 4.4 7.1 0.0 3.4 2 2 1 3 3 3 2 Poxvirus A22 protein RGS PF00615.14 CAR30723.1 - 0.0078 16.3 0.1 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain Flavoprotein PF02441.14 CAR30725.1 - 8.9e-42 141.8 0.0 1.5e-41 141.1 0.0 1.4 1 0 0 1 1 1 1 Flavoprotein CKAP2_C PF15297.1 CAR30725.1 - 0.38 9.5 8.7 0.89 8.3 6.1 1.6 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus zf-Tim10_DDP PF02953.10 CAR30726.1 - 1.2e-24 85.3 2.8 1.5e-24 85.0 1.9 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 CAR30726.1 - 0.018 14.4 4.0 0.022 14.1 2.7 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Cyto_heme_lyase PF01265.12 CAR30727.1 - 5.7e-88 294.8 6.8 6.3e-88 294.7 4.7 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase CDI PF02234.14 CAR30727.1 - 0.41 10.4 2.6 4.9 7.0 0.4 2.4 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor G-alpha PF00503.15 CAR30728.1 - 6.9e-119 397.0 7.3 9.1e-119 396.6 5.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CAR30728.1 - 1.1e-14 54.1 1.3 5.5e-10 38.7 0.0 2.8 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CAR30728.1 - 0.00024 20.3 0.3 0.039 13.0 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 CAR30728.1 - 0.0023 18.4 0.1 2.9 8.4 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 CAR30728.1 - 0.07 12.6 0.3 0.16 11.5 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 CAR30728.1 - 0.095 12.1 0.0 2.2 7.6 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ParBc PF02195.13 CAR30729.1 - 9.1e-14 51.3 0.0 1e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 ParB-like nuclease domain Ldh_1_C PF02866.13 CAR30730.1 - 1.1e-47 161.9 0.1 1.9e-47 161.1 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 CAR30730.1 - 4.9e-43 146.3 0.0 6.9e-43 145.8 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 CAR30730.1 - 0.00014 20.7 0.0 0.00019 20.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family zf-CHY PF05495.7 CAR30731.1 - 2e-14 53.4 15.5 2.7e-14 53.0 10.7 1.2 1 0 0 1 1 1 1 CHY zinc finger Cytochrome_C7 PF14522.1 CAR30731.1 - 0.014 15.0 9.2 0.026 14.1 6.4 1.5 1 0 0 1 1 1 0 Cytochrome c7 HypA PF01155.14 CAR30731.1 - 0.25 11.0 9.3 0.35 10.5 4.3 2.0 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Cytochrom_c3_2 PF14537.1 CAR30731.1 - 6.1 7.2 12.6 10 6.5 8.7 1.5 1 1 0 1 1 1 0 Cytochrome c3 Ank_2 PF12796.2 CAR30732.1 - 4.5e-23 81.3 0.1 9.6e-11 41.8 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CAR30732.1 - 8.2e-23 79.0 4.3 4.1e-05 23.1 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 CAR30732.1 - 1.7e-21 76.1 1.4 1.2e-05 25.7 0.1 4.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CAR30732.1 - 3e-13 48.6 2.1 0.016 15.3 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 CAR30732.1 - 2.3e-11 43.5 3.3 1.1e-05 25.5 0.0 4.7 3 2 3 6 6 6 3 Ankyrin repeats (many copies) TUG-UBL1 PF11470.3 CAR30733.1 - 3.3e-24 84.5 0.5 1.1e-23 82.8 0.0 2.2 2 0 0 2 2 2 1 GLUT4 regulating protein TUG UBX PF00789.15 CAR30733.1 - 2.2e-14 53.2 0.5 6.9e-14 51.6 0.1 2.0 2 0 0 2 2 2 1 UBX domain UN_NPL4 PF11543.3 CAR30733.1 - 0.038 14.2 0.0 0.42 10.9 0.0 2.3 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 SURF6 PF04935.7 CAR30735.1 - 1.3e-50 171.6 52.0 1.3e-50 171.6 36.0 4.1 2 1 0 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.1 CAR30735.1 - 2.5e-19 69.1 5.2 2.5e-19 69.1 3.6 7.7 5 3 2 7 7 7 1 60S ribosome biogenesis protein Rrp14 DUF4224 PF13986.1 CAR30735.1 - 0.051 13.1 0.4 0.15 11.5 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) EF1G PF00647.14 CAR30736.1 - 5e-44 148.3 0.1 9.9e-44 147.4 0.1 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 CAR30736.1 - 6.7e-13 48.4 0.1 6.7e-13 48.4 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CAR30736.1 - 6.4e-07 29.4 0.8 2.7e-06 27.4 0.0 2.4 3 1 1 4 4 4 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CAR30736.1 - 1.2e-06 28.9 0.2 1.2e-06 28.9 0.2 2.2 2 1 1 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CAR30736.1 - 1.7e-05 24.6 0.1 3.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CAR30736.1 - 0.00014 22.0 0.0 0.00028 21.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain V-ATPase_C PF03223.10 CAR30737.1 - 3.8e-122 407.7 0.7 4.3e-122 407.6 0.5 1.0 1 0 0 1 1 1 1 V-ATPase subunit C NUC130_3NT PF08158.7 CAR30737.1 - 0.002 18.3 0.7 1.2 9.5 0.0 2.6 2 0 0 2 2 2 2 NUC130/3NT domain Kinesin PF00225.18 CAR30738.1 - 1.9e-59 201.0 9.8 1.9e-59 201.0 6.8 2.4 2 1 0 2 2 2 1 Kinesin motor domain Tht1 PF04163.7 CAR30739.1 - 1.1e-50 172.6 34.2 3.9e-49 167.4 23.7 2.1 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein HSDR_N_2 PF13588.1 CAR30739.1 - 0.09 12.5 2.1 0.18 11.6 0.3 2.3 1 1 1 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) Tet_JBP PF12851.2 CAR30739.1 - 0.1 11.9 1.3 1.1 8.4 0.1 2.8 1 1 1 3 3 3 0 Oxygenase domain of the 2OGFeDO superfamily MCPsignal PF00015.16 CAR30739.1 - 2.9 7.3 6.5 6.3 6.2 0.0 3.1 1 1 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Baculo_PEP_C PF04513.7 CAR30739.1 - 4.9 6.9 20.0 0.27 11.0 2.4 3.4 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SUR7 PF06687.7 CAR30741.1 - 1.1e-21 77.3 15.3 1.5e-21 76.9 10.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF4013 PF13197.1 CAR30741.1 - 7.5 5.8 15.1 0.27 10.5 4.4 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF4013) HA2 PF04408.18 CAR30742.1 - 4.9e-15 55.3 0.0 9.2e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CAR30742.1 - 5.2e-13 48.6 0.0 1.4e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 CAR30742.1 - 2.6e-12 46.5 0.0 4.7e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 CAR30742.1 - 3.2e-09 36.4 0.2 5.7e-09 35.6 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CAR30742.1 - 0.00012 22.2 0.2 0.00026 21.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CAR30742.1 - 0.0022 17.4 0.2 0.0086 15.5 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain Flavi_DEAD PF07652.9 CAR30742.1 - 0.0077 15.9 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Flavivirus DEAD domain DUF258 PF03193.11 CAR30742.1 - 0.018 14.2 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Herpes_Helicase PF02689.9 CAR30742.1 - 0.02 12.6 0.0 0.031 12.0 0.0 1.2 1 0 0 1 1 1 0 Helicase DUF1355 PF07090.6 CAR30742.1 - 0.06 12.7 0.1 0.15 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1355) AAA_30 PF13604.1 CAR30742.1 - 0.073 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 CAR30742.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 CAR30742.1 - 0.23 11.2 0.6 2.7 7.7 0.4 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 CAR30742.1 - 0.24 11.7 0.8 0.6 10.3 0.6 1.7 1 1 0 1 1 1 0 ABC transporter Sugar_tr PF00083.19 CAR30743.1 - 9.6e-108 360.6 27.2 1.2e-107 360.3 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR30743.1 - 4.1e-28 98.1 31.3 2.4e-20 72.5 4.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CAR30744.1 - 8.4e-110 367.4 29.0 1e-109 367.1 20.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR30744.1 - 5e-22 78.0 52.2 1.3e-20 73.4 17.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily ArgJ PF01960.13 CAR30745.1 - 2.6e-145 483.6 5.6 3e-145 483.5 3.9 1.0 1 0 0 1 1 1 1 ArgJ family Suf PF05843.9 CAR30746.1 - 4.5e-73 246.4 16.3 5e-64 216.7 5.0 3.5 2 1 1 3 3 3 3 Suppressor of forked protein (Suf) TPR_14 PF13428.1 CAR30746.1 - 0.049 14.2 0.0 2.1 9.2 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Tom37_C PF11801.3 CAR30747.1 - 5.6e-38 130.4 2.3 7.9e-38 129.9 1.6 1.2 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 CAR30747.1 - 5.8e-22 77.7 0.1 1.1e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein DUF4369 PF14289.1 CAR30747.1 - 0.14 12.1 0.3 0.78 9.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4369) Sen15 PF09631.5 CAR30748.1 - 3.8e-27 94.4 0.0 4.4e-27 94.2 0.0 1.0 1 0 0 1 1 1 1 Sen15 protein DUF4448 PF14610.1 CAR30749.1 - 6.4e-57 192.1 0.5 9.9e-57 191.4 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Sorb PF02208.11 CAR30749.1 - 0.092 12.1 0.4 2.2 7.7 0.0 2.7 2 0 0 2 2 2 0 Sorbin homologous domain DUF4484 PF14831.1 CAR30750.1 - 0.099 12.7 3.2 0.23 11.5 2.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Cu-oxidase_2 PF07731.9 CAR30751.1 - 2.2e-47 160.0 4.2 3.8e-41 139.8 0.3 2.9 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 CAR30751.1 - 1e-43 147.8 2.6 5.1e-40 135.8 0.4 2.8 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 CAR30751.1 - 2.8e-34 118.3 6.3 9.2e-34 116.6 0.3 3.5 3 1 0 3 3 3 1 Multicopper oxidase Cupredoxin_1 PF13473.1 CAR30751.1 - 0.034 14.0 0.0 1.5 8.7 0.0 3.3 2 2 1 3 3 3 0 Cupredoxin-like domain PPC PF04151.10 CAR30751.1 - 0.053 14.4 0.2 0.65 11.0 0.0 2.8 3 1 0 3 3 3 0 Bacterial pre-peptidase C-terminal domain PetG PF02529.10 CAR30751.1 - 0.14 11.7 0.7 0.28 10.7 0.5 1.5 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 Mito_carr PF00153.22 CAR30753.1 - 8.1e-71 233.8 5.5 1.6e-25 88.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RabGAP-TBC PF00566.13 CAR30754.1 - 4.5e-37 127.5 1.4 4.5e-37 127.5 0.9 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain RRM_5 PF13893.1 CAR30755.1 - 1.9e-05 24.3 0.0 8.3e-05 22.3 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAR30755.1 - 5.9e-05 22.6 0.0 0.00074 19.1 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR30755.1 - 0.00067 19.5 0.0 0.0028 17.6 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) HSP70 PF00012.15 CAR30756.1 - 3.6e-54 183.7 0.8 3.6e-54 183.7 0.6 2.4 1 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 CAR30756.1 - 0.0013 17.4 0.0 0.0086 14.6 0.0 2.2 1 1 0 1 1 1 1 MreB/Mbl protein Dynactin_p22 PF07426.6 CAR30756.1 - 0.0032 16.7 3.2 0.0092 15.2 2.3 1.8 1 0 0 1 1 1 1 Dynactin subunit p22 Hydantoinase_A PF01968.13 CAR30756.1 - 0.048 12.7 0.1 0.15 11.1 0.0 1.8 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase DUF1168 PF06658.7 CAR30756.1 - 0.13 11.7 11.9 0.39 10.2 8.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) HrpB7 PF09486.5 CAR30756.1 - 1.3 8.8 10.6 0.062 13.2 0.4 3.1 3 1 0 4 4 4 0 Bacterial type III secretion protein (HrpB7) V_ATPase_I PF01496.14 CAR30757.1 - 1.5e-280 932.3 7.0 1.9e-280 932.1 4.9 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family AreA_N PF07573.6 CAR30757.1 - 0.19 12.3 0.2 0.5 10.9 0.1 1.6 1 0 0 1 1 1 0 Nitrogen regulatory protein AreA N terminus CNP1 PF08750.6 CAR30758.1 - 0.013 15.1 0.3 0.034 13.8 0.2 1.6 1 0 0 1 1 1 0 CNP1-like family LRAT PF04970.8 CAR30759.1 - 0.041 13.8 0.6 1.2 9.0 0.4 2.3 1 1 0 1 1 1 0 Lecithin retinol acyltransferase ABC1 PF03109.11 CAR30760.1 - 1.1e-36 125.4 0.0 2e-36 124.5 0.0 1.5 1 0 0 1 1 1 1 ABC1 family HA2 PF04408.18 CAR30761.1 - 7.8e-26 90.0 0.0 7.8e-26 90.0 0.0 1.8 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CAR30761.1 - 7.9e-25 86.9 0.0 1.9e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CAR30761.1 - 3.5e-11 42.8 0.0 8.1e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAR30761.1 - 1.3e-08 34.5 0.3 2.5e-08 33.6 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CAR30761.1 - 3.6e-06 27.1 0.1 1.3e-05 25.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 CAR30761.1 - 2.6e-05 23.7 0.1 7.9e-05 22.1 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.10 CAR30761.1 - 0.00028 20.7 0.5 0.18 11.6 0.0 2.7 3 0 0 3 3 2 2 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 CAR30761.1 - 0.0014 18.4 0.1 0.0029 17.3 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain T2SE PF00437.15 CAR30761.1 - 0.012 14.5 0.0 0.026 13.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.1 CAR30761.1 - 0.018 15.3 0.0 0.09 13.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 CAR30761.1 - 0.029 13.9 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 CAR30761.1 - 0.15 11.6 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Nab2 PF11517.3 CAR30763.1 - 5.4e-45 151.8 1.7 7.8e-45 151.3 1.2 1.2 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) zf-CCCH_2 PF14608.1 CAR30763.1 - 9.3e-15 53.9 66.5 9.5e-06 25.4 2.2 7.5 7 1 0 7 7 7 6 Zinc finger C-x8-C-x5-C-x3-H type DUF2508 PF10704.4 CAR30763.1 - 0.036 14.2 0.1 0.073 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) DUF1192 PF06698.6 CAR30763.1 - 1.7 8.5 4.0 3.2 7.6 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Ribosomal_S5 PF00333.15 CAR30764.1 - 1.2e-28 98.6 2.8 2.9e-28 97.3 1.9 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 CAR30764.1 - 1.7e-21 75.2 0.0 2.9e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.1 CAR30764.1 - 6.1 7.3 7.5 0.43 11.0 1.8 1.6 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Apolipoprotein PF01442.13 CAR30765.1 - 0.0032 17.0 1.0 0.0039 16.7 0.7 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain MAGE_N PF12440.3 CAR30765.1 - 0.0057 16.9 6.9 0.0075 16.5 4.8 1.1 1 0 0 1 1 1 1 Melanoma associated antigen family N terminal Rep_fac_C PF08542.6 CAR30765.1 - 0.034 14.1 0.0 0.21 11.6 0.0 2.2 2 1 1 3 3 3 0 Replication factor C C-terminal domain RRF PF01765.14 CAR30765.1 - 0.063 12.7 1.6 0.087 12.2 1.1 1.2 1 0 0 1 1 1 0 Ribosome recycling factor DUF3549 PF12069.3 CAR30765.1 - 0.075 11.7 0.3 0.093 11.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) His_Phos_1 PF00300.17 CAR30765.1 - 0.093 12.8 0.1 0.096 12.7 0.1 1.1 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) EBP PF05241.7 CAR30765.1 - 0.14 11.1 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Emopamil binding protein RPOL_N PF14700.1 CAR30765.1 - 0.19 10.9 1.9 0.23 10.6 1.3 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal DUF4473 PF14747.1 CAR30765.1 - 0.35 11.1 3.4 0.19 11.9 0.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) DUF883 PF05957.8 CAR30765.1 - 3.5 8.0 10.2 19 5.7 7.1 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Mon1 PF03164.9 CAR30766.1 - 6.3e-129 430.2 0.3 8e-129 429.8 0.2 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 GATA PF00320.22 CAR30767.1 - 9.7e-16 56.8 2.9 2.5e-15 55.4 2.0 1.8 1 0 0 1 1 1 1 GATA zinc finger Glyco_hydro_31 PF01055.21 CAR30768.1 - 3.1e-133 444.8 1.0 5.1e-133 444.1 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CAR30768.1 - 3.1e-18 65.4 2.7 4.5e-18 64.8 0.0 2.8 3 0 0 3 3 3 1 Galactose mutarotase-like Glyco_hydro_31 PF01055.21 CAR30769.1 - 9.3e-134 446.5 0.1 1.5e-133 445.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CAR30769.1 - 3.5e-22 78.0 0.1 1.2e-21 76.2 0.1 2.1 1 0 0 1 1 1 1 Galactose mutarotase-like GIY-YIG PF01541.19 CAR30770.1 - 1.2e-08 35.1 0.0 7.4e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 GIY-YIG catalytic domain FANCL_C PF11793.3 CAR30770.1 - 0.00023 21.0 2.8 0.00052 19.9 2.0 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.1 CAR30770.1 - 0.064 13.0 3.5 0.2 11.5 2.5 1.9 1 1 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.2 CAR30770.1 - 0.076 13.1 1.6 0.17 12.0 1.1 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger zf-CSL PF05207.8 CAR30770.1 - 0.094 12.2 2.1 2.4 7.7 1.5 2.3 1 1 0 1 1 1 0 CSL zinc finger zf-RING-like PF08746.6 CAR30770.1 - 0.2 11.7 3.4 0.14 12.1 0.4 2.1 2 0 0 2 2 2 0 RING-like domain DUF329 PF03884.9 CAR30770.1 - 0.24 10.9 3.8 7.8 6.1 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF329) zf-Apc11 PF12861.2 CAR30770.1 - 0.36 10.6 3.9 1.5 8.6 2.7 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger AAA_2 PF07724.9 CAR30771.1 - 6.5e-36 123.8 0.7 1.4e-35 122.6 0.5 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 CAR30771.1 - 5.8e-14 52.4 0.3 1e-13 51.6 0.2 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 CAR30771.1 - 1.7e-08 34.2 0.0 4.5e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 CAR30771.1 - 2.9e-07 30.2 0.1 8.5e-07 28.7 0.0 1.8 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CAR30771.1 - 5.1e-06 25.7 0.2 0.0016 17.6 0.1 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 CAR30771.1 - 7e-05 22.9 1.3 0.00092 19.3 0.1 3.1 3 2 1 4 4 3 1 AAA domain AAA_17 PF13207.1 CAR30771.1 - 0.00056 20.7 0.5 0.0035 18.1 0.1 2.7 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CAR30771.1 - 0.00088 18.7 0.0 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 CAR30771.1 - 0.0016 17.5 0.0 0.018 14.1 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 CAR30771.1 - 0.0025 17.6 0.0 0.02 14.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CAR30771.1 - 0.0044 17.0 0.0 0.031 14.2 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.21 CAR30771.1 - 0.0047 16.4 0.0 0.42 10.0 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 CAR30771.1 - 0.015 15.2 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 CAR30771.1 - 0.023 13.9 0.0 0.052 12.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.1 CAR30771.1 - 0.035 13.6 0.1 0.094 12.2 0.1 1.8 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 CAR30771.1 - 0.044 13.8 0.0 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain DEAD PF00270.24 CAR30771.1 - 0.052 13.0 3.5 0.4 10.1 0.1 3.3 2 2 1 4 4 4 0 DEAD/DEAH box helicase RNA_helicase PF00910.17 CAR30771.1 - 0.091 12.9 0.3 0.33 11.1 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.1 CAR30771.1 - 0.1 12.9 0.2 0.1 12.9 0.1 2.6 3 1 0 3 3 2 0 AAA domain Methyltransf_11 PF08241.7 CAR30772.1 - 6.8e-05 23.2 0.0 0.00019 21.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAR30772.1 - 0.0067 16.1 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTHFR PF02219.12 CAR30773.1 - 1e-118 395.6 0.0 1.3e-118 395.2 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Tyr-DNA_phospho PF06087.7 CAR30775.1 - 2.5e-95 319.7 2.3 2.9e-95 319.5 1.6 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 CAR30775.1 - 0.0011 18.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 PLD-like domain AMP-binding PF00501.23 CAR30776.1 - 1e-73 248.1 0.0 1.4e-73 247.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CAR30776.1 - 1.1e-17 64.7 0.3 5.1e-17 62.5 0.1 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Mito_carr PF00153.22 CAR30777.1 - 4.2e-54 180.2 7.4 3.2e-18 65.2 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_transf_15 PF01793.11 CAR30778.1 - 3.1e-139 463.5 7.8 3.7e-139 463.2 5.4 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Staygreen PF12638.2 CAR30778.1 - 0.073 12.6 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Staygreen protein Nucleoporin_FG PF13634.1 CAR30779.1 - 1.3e-10 41.5 148.7 9.1e-07 29.1 11.9 7.5 1 1 5 6 6 6 4 Nucleoporin FG repeat region SHIPPO-rpt PF07004.7 CAR30779.1 - 0.64 11.0 71.7 1.1e+02 3.9 1.7 17.7 4 3 1 5 5 5 0 Sperm-tail PG-rich repeat Ribosomal_S7e PF01251.13 CAR30781.1 - 4.3e-81 270.9 1.8 5e-81 270.7 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Rib_5-P_isom_A PF06026.9 CAR30782.1 - 1.1e-54 184.4 0.0 1.4e-54 183.9 0.0 1.2 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 CAR30782.1 - 0.014 14.9 0.0 5.6 6.5 0.0 2.3 2 0 0 2 2 2 0 DeoR C terminal sensor domain Arf PF00025.16 CAR30783.1 - 2.8e-71 238.3 0.2 3.2e-71 238.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CAR30783.1 - 2e-14 53.2 0.0 2.4e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CAR30783.1 - 5.5e-14 51.8 0.0 6.5e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CAR30783.1 - 1.3e-13 50.4 0.6 2.9e-09 36.1 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CAR30783.1 - 5.4e-11 42.0 0.0 6.2e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CAR30783.1 - 2.1e-09 37.9 0.0 2.9e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CAR30783.1 - 3.1e-06 27.1 0.0 4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 CAR30783.1 - 0.12 11.4 0.4 0.2 10.6 0.1 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase AMP-binding PF00501.23 CAR30784.1 - 9e-35 119.8 0.0 1.1e-12 47.0 0.0 4.4 4 1 0 4 4 4 4 AMP-binding enzyme DMAP_binding PF06464.6 CAR30784.1 - 6.4e-11 42.8 0.1 2.4e-10 41.0 0.0 2.0 2 0 0 2 2 2 1 DMAP1-binding Domain Mem_trans PF03547.13 CAR30785.1 - 4.1e-76 255.7 0.1 6e-76 255.2 0.1 1.2 1 0 0 1 1 1 1 Membrane transport protein Sugar_tr PF00083.19 CAR30786.1 - 1.8e-76 257.5 29.3 2.1e-76 257.3 20.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR30786.1 - 2.4e-12 46.2 34.1 2.4e-12 46.2 23.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1700 PF08006.6 CAR30786.1 - 2 7.6 6.7 5.4 6.2 4.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) 4HBT PF03061.17 CAR30787.1 - 2e-05 24.6 0.0 3.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Asp PF00026.18 CAR30788.1 - 3.3e-69 233.5 4.4 6.2e-69 232.6 3.1 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CAR30788.1 - 5.4e-06 26.4 0.0 3.5e-05 23.8 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CAR30788.1 - 0.0023 18.4 0.3 5.5 7.5 0.0 3.4 3 0 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 CAR30788.1 - 0.011 15.2 0.1 0.15 11.6 0.0 2.2 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal MFS_1 PF07690.11 CAR30789.1 - 8e-30 103.7 16.0 8e-30 103.7 11.1 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4131 PF13567.1 CAR30789.1 - 1.8 7.9 0.0 1.8 7.9 0.0 4.1 4 1 1 5 5 5 0 Domain of unknown function (DUF4131) ArfGap PF01412.13 CAR30790.1 - 3e-33 114.0 1.2 3e-33 114.0 0.9 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Rox3 PF08633.5 CAR30791.1 - 1.8e-59 201.3 0.9 2.2e-59 201.0 0.6 1.1 1 0 0 1 1 1 1 Rox3 mediator complex subunit SHNi-TPR PF10516.4 CAR30791.1 - 0.046 12.9 0.0 2.1 7.6 0.0 2.3 2 0 0 2 2 2 0 SHNi-TPR Pkinase PF00069.20 CAR30793.1 - 4.7e-27 94.7 0.0 6.9e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR30793.1 - 6e-08 32.0 0.0 9.5e-08 31.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3354 PF11834.3 CAR30793.1 - 0.068 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3354) Peptidase_M44 PF03410.8 CAR30793.1 - 0.23 9.7 0.0 0.35 9.0 0.0 1.2 1 0 0 1 1 1 0 Protein G1 MRG PF05712.8 CAR30794.1 - 4.5e-45 152.9 0.0 4.5e-45 152.9 0.0 1.5 2 0 0 2 2 2 1 MRG Tudor-knot PF11717.3 CAR30794.1 - 1.9e-07 30.7 0.1 6.8e-07 28.9 0.1 2.0 1 1 0 1 1 1 1 RNA binding activity-knot of a chromodomain Mito_carr PF00153.22 CAR30795.1 - 2.5e-73 241.8 0.4 8e-25 86.3 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 CAR30795.1 - 0.042 13.9 1.2 0.65 10.1 0.2 3.4 2 0 0 2 2 2 0 EF-hand domain pair Bud13 PF09736.4 CAR30797.1 - 1.6e-27 96.5 5.7 1.6e-27 96.5 4.0 3.8 1 1 1 2 2 2 1 Pre-mRNA-splicing factor of RES complex XRN_N PF03159.13 CAR30798.1 - 3.6e-100 334.2 0.1 7.5e-100 333.1 0.1 1.6 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus DUF3510 PF12022.3 CAR30798.1 - 3.3 7.8 7.2 0.16 12.0 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) Nucleoporin_FG PF13634.1 CAR30799.1 - 8.2e-34 116.2 181.8 3.4e-11 43.3 39.6 5.5 1 1 4 5 5 5 5 Nucleoporin FG repeat region Terpene_synth PF01397.16 CAR30799.1 - 0.068 12.5 0.7 0.11 11.8 0.5 1.2 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain DUF1664 PF07889.7 CAR30799.1 - 0.3 10.9 2.6 1.3 8.8 0.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DEAD PF00270.24 CAR30800.1 - 2.2e-42 144.4 0.0 4.1e-42 143.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR30800.1 - 4.3e-26 90.5 0.1 2.9e-25 87.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAR30800.1 - 0.001 18.9 1.1 0.0064 16.3 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 CAR30800.1 - 0.011 15.6 0.0 0.071 13.0 0.0 2.1 2 0 0 2 2 2 0 Helicase C-terminal domain T4SS-DNA_transf PF02534.9 CAR30800.1 - 0.026 13.1 0.3 3.5 6.1 0.0 2.2 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer ATP-synt_G PF04718.10 CAR30801.1 - 8.1e-27 93.8 0.1 9.5e-27 93.6 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit MCM PF00493.18 CAR30802.1 - 1.1e-139 464.9 0.2 1.5e-139 464.4 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CAR30802.1 - 7.3e-24 84.5 7.0 2e-23 83.1 3.0 3.1 3 1 0 3 3 3 1 MCM N-terminal domain AAA_5 PF07728.9 CAR30802.1 - 3.6e-06 26.7 0.1 3.5e-05 23.5 0.0 2.7 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CAR30802.1 - 1.5e-05 24.3 0.0 0.00053 19.2 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CAR30802.1 - 0.0015 18.1 0.0 0.0099 15.4 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CAR30802.1 - 0.059 12.8 0.2 3.9 6.9 0.0 3.1 3 0 0 3 3 3 0 Sigma-54 interaction domain CAF1A PF12253.3 CAR30803.1 - 3.5e-22 78.2 9.5 3.5e-22 78.2 6.6 4.8 3 1 1 4 4 4 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 CAR30803.1 - 8.1e-12 44.9 87.0 8.1e-12 44.9 60.3 2.8 2 1 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Sin3_corepress PF08295.7 CAR30804.1 - 0.099 12.4 6.5 0.23 11.2 2.6 2.6 2 0 0 2 2 2 0 Sin3 family co-repressor Sod_Fe_N PF00081.17 CAR30804.1 - 0.25 11.6 0.0 0.25 11.6 0.0 3.0 3 0 0 3 3 3 0 Iron/manganese superoxide dismutases, alpha-hairpin domain eIF-6 PF01912.13 CAR30805.1 - 2.4e-85 284.6 0.5 3e-85 284.3 0.4 1.1 1 0 0 1 1 1 1 eIF-6 family zf-C2H2 PF00096.21 CAR30806.1 - 2.5e-09 36.9 10.7 0.00021 21.4 1.0 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CAR30806.1 - 3.9e-06 26.8 8.8 0.00014 21.9 0.3 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CAR30806.1 - 4.8e-06 26.5 8.5 0.0041 17.3 0.7 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 CAR30806.1 - 0.00014 21.9 6.6 0.006 16.7 0.3 2.3 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CAR30806.1 - 0.00086 19.3 2.9 0.14 12.3 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zinc_ribbon_4 PF13717.1 CAR30806.1 - 0.083 12.5 1.1 4.5 7.0 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CAR30806.1 - 0.094 12.3 1.1 4 7.0 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-BED PF02892.10 CAR30806.1 - 0.19 11.4 7.2 0.82 9.4 1.4 2.3 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_5 PF13909.1 CAR30806.1 - 0.36 11.1 10.5 2.3 8.5 1.4 2.7 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.2 CAR30806.1 - 0.65 10.1 5.5 1.5 8.9 0.1 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-tcix PF14952.1 CAR30806.1 - 0.71 9.2 5.0 0.76 9.1 0.3 2.3 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding Mito_carr PF00153.22 CAR30807.1 - 8.4e-74 243.3 2.2 5.3e-26 90.1 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 CAR30807.1 - 0.1 12.4 0.1 0.91 9.3 0.0 2.6 4 0 0 4 4 4 0 UcrQ family B12D PF06522.6 CAR30808.1 - 0.0041 16.7 0.0 0.0059 16.2 0.0 1.4 1 1 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit AIF-MLS PF14962.1 CAR30808.1 - 0.048 13.3 0.0 0.051 13.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondria Localisation Sequence Xan_ur_permease PF00860.15 CAR30809.1 - 3.6e-61 206.7 25.7 5.6e-61 206.1 17.8 1.2 1 0 0 1 1 1 1 Permease family RNA_pol_Rpb2_6 PF00562.23 CAR30810.1 - 2.3e-113 378.8 0.0 3.2e-113 378.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CAR30810.1 - 2.1e-48 163.9 0.0 2.9e-48 163.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 CAR30810.1 - 7.4e-34 116.8 0.0 1.4e-33 115.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 CAR30810.1 - 7.4e-25 86.4 0.0 4.7e-24 83.9 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 CAR30810.1 - 6.2e-22 77.3 0.0 1.6e-21 75.9 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 CAR30810.1 - 5.1e-16 58.6 0.0 4e-15 55.8 0.0 2.3 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 CAR30810.1 - 1e-05 25.4 0.1 2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 E1-E2_ATPase PF00122.15 CAR30811.1 - 3.1e-77 258.6 1.0 4.7e-77 258.1 0.1 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CAR30811.1 - 1.5e-47 161.4 1.8 1.5e-47 161.4 1.2 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CAR30811.1 - 6e-32 111.8 0.0 1.1e-31 110.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CAR30811.1 - 3e-19 68.7 0.1 7e-19 67.5 0.1 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CAR30811.1 - 2.7e-18 66.8 0.0 5.6e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CAR30811.1 - 3e-14 52.2 0.0 2e-13 49.5 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CAR30811.1 - 0.00036 20.2 2.1 0.0016 18.0 0.7 2.3 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Sua5_yciO_yrdC PF01300.13 CAR30812.1 - 6.3e-49 165.6 0.0 9.9e-49 164.9 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 CAR30812.1 - 2.4e-32 111.6 0.0 3.6e-32 111.0 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding CDC27 PF09507.5 CAR30814.1 - 2.4e-08 33.6 41.2 7.3e-07 28.7 26.7 2.2 2 0 0 2 2 2 2 DNA polymerase subunit Cdc27 LsmAD PF06741.8 CAR30814.1 - 3.9 7.6 8.4 12 6.0 5.8 1.9 1 0 0 1 1 1 0 LsmAD domain ATP-synt_C PF00137.16 CAR30815.1 - 5.6e-31 106.2 29.7 7.9e-18 64.1 6.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF2970 PF11174.3 CAR30815.1 - 0.83 9.2 8.4 0.57 9.7 1.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Nucleopor_Nup85 PF07575.8 CAR30816.1 - 3.1e-158 527.5 8.3 3.6e-158 527.3 5.7 1.0 1 0 0 1 1 1 1 Nup85 Nucleoporin Urb2 PF10441.4 CAR30817.1 - 2.5e-52 177.7 1.1 2.5e-52 177.7 0.8 2.7 3 0 0 3 3 3 1 Urb2/Npa2 family Transposase_28 PF04195.7 CAR30817.1 - 0.047 12.9 0.1 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 Putative gypsy type transposon Voltage_CLC PF00654.15 CAR30818.1 - 4.9e-79 265.9 23.7 4.9e-79 265.9 16.4 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 CAR30818.1 - 6.4e-14 51.4 0.2 7.5e-08 32.0 0.0 2.7 2 0 0 2 2 2 2 CBS domain Ribosomal_L7Ae PF01248.21 CAR30819.1 - 1e-26 92.2 0.0 1.2e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CAR30819.1 - 0.0056 16.5 0.0 0.0063 16.3 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 CAR30819.1 - 0.029 14.1 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain YqaJ PF09588.5 CAR30820.1 - 0.01 15.7 0.0 3.2 7.7 0.0 2.4 2 0 0 2 2 2 0 YqaJ-like viral recombinase domain HECT PF00632.20 CAR30822.1 - 1.3e-82 277.4 0.5 3.6e-82 276.0 0.2 1.9 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) zf-LSD1 PF06943.7 CAR30822.1 - 0.15 11.6 7.6 0.078 12.6 2.8 2.4 3 0 0 3 3 3 0 LSD1 zinc finger Cys_rich_CPCC PF14206.1 CAR30822.1 - 2.6 7.6 7.5 6.3 6.4 3.1 2.5 2 1 0 2 2 2 0 Cysteine-rich CPCC Rieske PF00355.21 CAR30823.1 - 1.6e-18 66.0 0.0 2.8e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.9 CAR30823.1 - 2.2e-18 66.2 1.7 4.5e-18 65.2 1.2 1.6 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region DUF2235 PF09994.4 CAR30824.1 - 1.2e-78 264.3 0.0 1.6e-78 263.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 CAR30824.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family IATP PF04568.7 CAR30824.1 - 0.21 11.6 1.9 0.58 10.2 0.2 2.2 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP SNF2_N PF00176.18 CAR30825.1 - 3.4e-77 259.1 0.0 5.5e-77 258.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CAR30825.1 - 3.9e-15 55.4 0.0 1.1e-14 53.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pet191_N PF10203.4 CAR30826.1 - 6.7e-25 86.9 3.2 9.4e-25 86.4 2.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.8 CAR30826.1 - 1.6 8.7 6.5 2.1 8.3 0.6 2.9 3 1 0 3 3 3 0 CHCH domain Rav1p_C PF12234.3 CAR30827.1 - 2.5e-252 838.6 2.1 5.9e-252 837.4 1.5 1.6 1 0 0 1 1 1 1 RAVE protein 1 C terminal DUF605 PF04652.11 CAR30827.1 - 0.0047 16.3 0.4 0.0071 15.7 0.3 1.2 1 0 0 1 1 1 1 Vta1 like Pro_isomerase PF00160.16 CAR30828.1 - 1.7e-40 138.7 0.1 3.6e-40 137.6 0.1 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 CAR30828.1 - 2.3e-09 36.7 11.8 1.6e-05 24.4 3.0 2.4 1 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 CAR30828.1 - 6.6e-09 35.0 12.1 7.7e-05 22.3 0.5 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CAR30828.1 - 2.6e-06 26.8 1.0 2.6e-06 26.8 0.7 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CAR30828.1 - 3.8e-06 26.7 4.1 5.7e-05 22.9 2.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 CAR30828.1 - 0.0017 18.9 1.0 0.0034 18.0 0.3 1.8 2 0 0 2 2 1 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CAR30828.1 - 0.022 14.6 4.7 0.039 13.8 1.2 2.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat SLT_L PF14718.1 CAR30828.1 - 0.035 13.8 0.6 0.12 12.2 0.1 2.0 2 0 0 2 2 2 0 Soluble lytic murein transglycosylase L domain TPR_6 PF13174.1 CAR30828.1 - 0.13 12.7 9.4 0.33 11.5 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 CAR30828.1 - 0.23 11.7 1.5 16 6.0 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 CAR30828.1 - 0.26 11.1 2.5 6 6.9 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 CAR30828.1 - 0.66 9.8 21.3 0.14 12.0 1.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Sec7 PF01369.15 CAR30829.1 - 3.7e-62 209.3 2.1 3.7e-62 209.3 1.4 2.1 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.2 CAR30829.1 - 5.9e-16 58.3 0.5 5.9e-16 58.3 0.3 2.5 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF2360 PF10152.4 CAR30829.1 - 0.0024 18.1 3.4 0.01 16.0 0.3 2.8 2 1 0 2 2 2 1 Predicted coiled-coil domain-containing protein (DUF2360) Mito_carr PF00153.22 CAR30830.1 - 2.3e-13 49.6 0.2 6e-10 38.6 0.0 3.0 4 0 0 4 4 4 2 Mitochondrial carrier protein OMPdecase PF00215.19 CAR30831.1 - 1.5e-76 256.7 0.0 1.7e-76 256.6 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family zf-Tim10_DDP PF02953.10 CAR30832.1 - 4.4e-21 73.9 3.5 5.7e-21 73.5 2.4 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Mmp37 PF09139.6 CAR30832.1 - 0.12 11.3 0.1 0.12 11.3 0.1 1.0 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 Vicilin_N PF04702.7 CAR30832.1 - 0.16 11.5 3.4 0.2 11.2 2.3 1.1 1 0 0 1 1 1 0 Vicilin N terminal region MFS_1 PF07690.11 CAR30833.1 - 1.6e-27 96.1 10.5 1e-22 80.3 0.6 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CAR30833.1 - 8.7e-10 37.7 3.6 8.7e-10 37.7 2.5 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 CAR30833.1 - 1.5e-05 23.5 3.5 1.5e-05 23.5 2.4 2.3 2 0 0 2 2 2 1 MFS/sugar transport protein TRI12 PF06609.8 CAR30833.1 - 0.0012 17.1 0.3 0.0021 16.3 0.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TPP_enzyme_N PF02776.13 CAR30834.1 - 2.7e-43 147.4 0.0 3.1e-42 143.9 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 CAR30834.1 - 5.6e-27 94.1 0.0 1.1e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 CAR30834.1 - 6.7e-22 77.7 0.0 1.8e-21 76.2 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain tRNA-synt_2 PF00152.15 CAR30835.1 - 8.3e-74 248.3 0.0 1e-73 248.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CAR30835.1 - 3.3e-08 33.2 0.0 6.1e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CAR30835.1 - 0.11 11.6 0.0 0.75 8.9 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) zf-Nse PF11789.3 CAR30836.1 - 7.1e-20 70.2 0.2 1.9e-19 68.9 0.2 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 CAR30836.1 - 0.0011 18.6 0.5 0.0011 18.6 0.3 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.1 CAR30836.1 - 0.0018 18.0 1.0 0.0061 16.3 0.3 2.2 1 1 1 2 2 2 1 Ring finger domain DUF1548 PF07579.6 CAR30836.1 - 0.011 15.8 1.5 3 7.9 0.1 2.2 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1548) zf-MIZ PF02891.15 CAR30836.1 - 0.017 14.5 0.2 0.071 12.6 0.1 2.1 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-C3HC4 PF00097.20 CAR30836.1 - 0.029 14.0 0.3 0.074 12.7 0.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAR30836.1 - 0.04 13.9 1.7 0.11 12.5 1.2 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) U-box PF04564.10 CAR30836.1 - 0.046 13.6 0.1 1 9.3 0.0 2.4 2 0 0 2 2 2 0 U-box domain DUF479 PF04336.7 CAR30836.1 - 0.065 13.3 0.5 6.6 6.8 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function, DUF479 IF-2B PF01008.12 CAR30836.1 - 0.15 11.0 0.4 0.2 10.5 0.2 1.1 1 0 0 1 1 1 0 Initiation factor 2 subunit family zf-C3HC4_4 PF15227.1 CAR30836.1 - 1.7 8.6 5.0 2.2 8.2 2.2 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Phosphodiest PF01663.17 CAR30839.1 - 5e-62 210.3 0.3 6.4e-62 209.9 0.2 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 CAR30839.1 - 0.00076 18.7 0.0 0.0013 18.0 0.0 1.5 1 0 0 1 1 1 1 Sulfatase adh_short_C2 PF13561.1 CAR30840.1 - 3.3e-22 79.4 0.0 1.2e-21 77.6 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CAR30840.1 - 2.8e-20 72.9 0.3 5.3e-19 68.7 0.2 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CAR30840.1 - 8.5e-13 48.3 0.2 1.8e-11 44.0 0.0 2.1 1 1 1 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 CAR30840.1 - 5.5e-06 25.4 0.0 7.9e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 CAR30840.1 - 5.7e-06 25.9 0.1 1.1e-05 25.0 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CAR30840.1 - 0.0036 16.0 0.0 0.005 15.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 CAR30840.1 - 0.0058 15.5 0.2 0.038 12.8 0.1 2.2 2 1 0 2 2 2 1 RmlD substrate binding domain 3HCDH_N PF02737.13 CAR30840.1 - 0.095 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ras PF00071.17 CAR30841.1 - 9.7e-43 145.3 0.1 1.2e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR30841.1 - 2.9e-14 53.6 0.0 4e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAR30841.1 - 2.7e-12 46.2 0.0 3.4e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CAR30841.1 - 6.2e-10 38.8 0.1 1.9e-07 30.6 0.0 2.0 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CAR30841.1 - 5.3e-06 26.3 0.0 6.8e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.1 CAR30841.1 - 0.0013 18.6 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.5 CAR30841.1 - 0.0021 17.2 0.0 0.003 16.7 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 CAR30841.1 - 0.0072 15.6 0.0 0.024 13.9 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Arch_ATPase PF01637.13 CAR30841.1 - 0.0083 15.8 0.2 0.014 15.1 0.1 1.6 1 1 0 1 1 1 1 Archaeal ATPase MobB PF03205.9 CAR30841.1 - 0.026 14.2 0.1 0.063 12.9 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 CAR30841.1 - 0.11 11.9 0.0 8.7 5.7 0.0 2.7 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.1 CAR30841.1 - 0.12 12.2 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain YjeF_N PF03853.10 CAR30842.1 - 4.7e-28 97.8 0.0 1e-27 96.8 0.0 1.6 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 CAR30842.1 - 3.3e-06 27.5 16.5 2.3e-05 24.8 11.1 2.2 1 1 0 1 1 1 1 FDF domain Arm PF00514.18 CAR30843.1 - 4.1e-69 226.2 31.2 4.1e-11 42.2 0.0 10.6 11 0 0 11 11 11 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CAR30843.1 - 1.5e-24 86.0 10.9 1.4e-06 28.5 0.1 7.3 2 2 5 7 7 7 6 HEAT repeats HEAT_EZ PF13513.1 CAR30843.1 - 5e-14 52.2 17.8 7.1e-05 23.1 0.3 7.6 6 1 3 9 9 8 4 HEAT-like repeat HEAT PF02985.17 CAR30843.1 - 3.7e-13 48.3 28.3 0.019 14.9 0.1 10.9 12 0 0 12 12 11 3 HEAT repeat Adaptin_N PF01602.15 CAR30843.1 - 9.2e-12 44.0 13.2 3.7e-07 28.8 1.1 3.3 1 1 2 3 3 3 2 Adaptin N terminal region KAP PF05804.7 CAR30843.1 - 6.3e-11 40.9 0.4 2.7e-10 38.8 0.3 1.9 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) Arm_2 PF04826.8 CAR30843.1 - 2.6e-10 39.8 8.7 1.6e-07 30.7 2.3 3.1 2 1 0 3 3 3 2 Armadillo-like V-ATPase_H_N PF03224.9 CAR30843.1 - 8.5e-05 21.8 1.1 0.0028 16.8 0.3 3.0 1 1 1 2 2 2 1 V-ATPase subunit H Vac14_Fab1_bd PF12755.2 CAR30843.1 - 9.4e-05 22.7 0.3 0.39 11.1 0.0 3.9 3 2 1 4 4 4 2 Vacuolar 14 Fab1-binding region DUF2454 PF10521.4 CAR30843.1 - 0.00036 19.6 0.1 0.07 12.1 0.0 2.5 3 0 0 3 3 3 2 Protein of unknown function (DUF2454) RIX1 PF08167.7 CAR30843.1 - 0.0007 19.3 1.0 0.013 15.1 0.1 3.0 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis V-ATPase_H_C PF11698.3 CAR30843.1 - 0.0083 16.0 2.3 1.2 9.0 0.1 4.1 2 1 4 6 6 6 1 V-ATPase subunit H PfkB PF00294.19 CAR30844.1 - 2e-12 46.8 0.0 2.8e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase TENA_THI-4 PF03070.11 CAR30845.1 - 6.3e-13 48.9 1.6 8e-13 48.6 1.1 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family LSM PF01423.17 CAR30846.1 - 3.7e-11 42.3 0.0 4.7e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain RepA_N PF06970.6 CAR30847.1 - 0.065 13.0 0.8 0.082 12.7 0.6 1.1 1 0 0 1 1 1 0 Replication initiator protein A (RepA) N-terminus UQ_con PF00179.21 CAR30848.1 - 7.7e-40 135.5 0.1 1e-39 135.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CAR30848.1 - 0.0085 15.9 0.0 0.014 15.2 0.0 1.6 1 1 0 1 1 1 1 RWD domain TFIIA PF03153.8 CAR30848.1 - 0.066 13.1 11.4 0.067 13.0 7.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Vfa1 PF08432.5 CAR30848.1 - 0.092 12.7 5.1 0.12 12.3 3.6 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.9 CAR30848.1 - 0.38 8.7 10.5 0.45 8.5 7.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 CAR30848.1 - 2.6 6.6 27.3 3 6.4 18.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 CAR30848.1 - 7.2 5.7 17.6 9.1 5.4 12.2 1.1 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.6 CAR30848.1 - 9.5 6.0 11.0 17 5.1 7.6 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Alpha-amylase_C PF02806.13 CAR30849.1 - 3.8e-24 84.6 0.2 2.8e-23 81.8 0.1 2.5 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 CAR30849.1 - 1.5e-17 64.0 0.3 1.3e-16 60.9 0.2 2.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain CBM_48 PF02922.13 CAR30849.1 - 1.7e-16 60.0 0.0 4.7e-16 58.5 0.0 1.8 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Glyco_hydro_66 PF13199.1 CAR30849.1 - 0.0025 16.3 0.1 0.0089 14.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 66 Frag1 PF10277.4 CAR30850.1 - 1.2e-29 103.3 7.5 1.2e-29 103.3 5.2 3.8 3 1 0 3 3 3 2 Frag1/DRAM/Sfk1 family DUF4228 PF14009.1 CAR30851.1 - 0.077 13.1 0.0 0.077 13.1 0.0 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4228) Sugar_tr PF00083.19 CAR30852.1 - 1.2e-105 353.7 24.3 1.5e-105 353.4 16.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR30852.1 - 1.5e-29 102.8 33.8 2.2e-26 92.4 12.5 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CAR30852.1 - 3.2e-07 29.0 8.6 1.3e-06 27.0 0.8 3.5 4 1 0 4 4 4 2 MFS/sugar transport protein TRI12 PF06609.8 CAR30852.1 - 0.0012 17.1 1.3 0.002 16.3 0.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4131 PF13567.1 CAR30852.1 - 0.52 9.6 9.9 6.3 6.1 0.1 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) DUF2373 PF10180.4 CAR30853.1 - 2.2e-24 84.7 0.5 5.9e-24 83.4 0.3 1.8 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) GCIP PF13324.1 CAR30853.1 - 0.65 9.1 8.4 0.17 11.0 1.7 2.4 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting HAD PF12710.2 CAR30854.1 - 5.6e-12 46.2 0.0 8.9e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DNA_pol_B_thumb PF14791.1 CAR30856.1 - 3.1e-16 58.8 0.1 8.7e-16 57.3 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 CAR30856.1 - 1.2e-15 57.5 0.0 3.4e-15 56.0 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.1 CAR30856.1 - 1e-11 44.7 0.1 2.1e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 CAR30856.1 - 3.7e-06 26.3 0.0 9e-06 25.1 0.0 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda Cdd1 PF11731.3 CAR30856.1 - 0.05 13.5 0.0 0.38 10.6 0.0 2.3 2 0 0 2 2 2 0 Pathogenicity locus PGK PF00162.14 CAR30857.1 - 3.1e-147 490.1 0.0 3.5e-147 489.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase ABC2_membrane PF01061.19 CAR30858.1 - 3.7e-37 127.5 17.9 3.7e-37 127.5 12.4 2.0 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.22 CAR30858.1 - 7.9e-29 100.7 0.0 1.7e-28 99.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 CAR30858.1 - 0.00013 21.2 0.3 0.00028 20.0 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 CAR30858.1 - 0.00026 20.4 0.3 0.056 12.8 0.2 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CAR30858.1 - 0.0035 16.8 0.1 0.0092 15.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 CAR30858.1 - 0.0047 16.9 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain EGF_2 PF07974.8 CAR30858.1 - 0.0048 17.0 6.4 0.0048 17.0 4.4 3.9 5 0 0 5 5 2 1 EGF-like domain SbcCD_C PF13558.1 CAR30858.1 - 0.053 13.4 0.0 0.13 12.1 0.0 1.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 CAR30858.1 - 0.069 13.2 0.0 0.22 11.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.1 CAR30858.1 - 0.093 12.6 0.3 0.16 11.8 0.2 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CAR30858.1 - 0.15 11.6 1.1 0.29 10.7 0.8 1.4 1 0 0 1 1 1 0 NACHT domain Laminin_EGF PF00053.19 CAR30858.1 - 0.45 10.4 33.5 0.032 14.1 4.6 4.1 3 1 0 3 3 2 0 Laminin EGF-like (Domains III and V) hEGF PF12661.2 CAR30858.1 - 7.4 6.8 21.4 0.18 11.9 2.6 3.4 3 0 0 3 3 2 0 Human growth factor-like EGF RNA_pol_Rpc34 PF05158.7 CAR30859.1 - 1.2e-97 327.0 1.1 1.4e-97 326.7 0.8 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.7 CAR30859.1 - 0.0018 18.0 1.7 0.059 13.2 0.1 2.4 1 1 1 2 2 2 1 B-block binding subunit of TFIIIC TrmB PF01978.14 CAR30859.1 - 0.023 14.3 0.6 7.7 6.3 0.2 2.7 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.15 CAR30859.1 - 0.043 13.9 0.6 0.084 13.0 0.1 1.7 2 0 0 2 2 2 0 Transcriptional regulator Cyclin_C PF02984.14 CAR30859.1 - 0.052 13.4 1.0 4.1 7.3 0.4 2.3 1 1 1 2 2 2 0 Cyclin, C-terminal domain GrpE PF01025.14 CAR30860.1 - 0.11 12.0 1.5 1 8.8 0.3 2.2 2 0 0 2 2 2 0 GrpE Grp1_Fun34_YaaH PF01184.14 CAR30861.1 - 1.6e-87 292.2 16.8 1.9e-87 292.0 11.6 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF373 PF04123.8 CAR30861.1 - 0.32 9.9 6.8 0.15 11.0 3.4 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF373) Grp1_Fun34_YaaH PF01184.14 CAR30862.1 - 9.1e-91 302.8 12.7 1.1e-90 302.5 8.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2165 PF09933.4 CAR30862.1 - 0.01 15.5 0.6 0.023 14.4 0.4 1.5 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2165) DUF373 PF04123.8 CAR30862.1 - 1.1 8.1 5.3 0.66 8.9 2.2 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF373) BAR PF03114.13 CAR30863.1 - 5.9e-53 179.7 2.5 7.1e-53 179.4 1.7 1.1 1 0 0 1 1 1 1 BAR domain AAA_23 PF13476.1 CAR30863.1 - 0.63 10.3 5.1 1.7 8.9 3.5 1.9 1 1 0 1 1 1 0 AAA domain Sterol-sensing PF12349.3 CAR30864.1 - 0.00028 20.3 0.9 0.00028 20.3 0.6 2.7 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Pkinase PF00069.20 CAR30865.1 - 3.9e-63 213.0 0.1 1e-62 211.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR30865.1 - 3.9e-24 85.1 0.0 6.5e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CAR30865.1 - 0.00021 21.0 0.0 0.00052 19.8 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CAR30865.1 - 0.00065 19.3 2.2 0.0012 18.4 0.1 2.2 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.9 CAR30865.1 - 0.0011 18.0 0.0 0.0027 16.7 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CAR30865.1 - 0.011 14.7 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Citrate_synt PF00285.16 CAR30866.1 - 1.3e-100 336.5 0.0 1.6e-100 336.2 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Flavodoxin_1 PF00258.20 CAR30867.1 - 3.4e-10 40.0 0.0 5.7e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin FMN_red PF03358.10 CAR30867.1 - 1.6e-09 37.4 0.0 2.7e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 CAR30867.1 - 4.5e-05 23.0 0.0 7.5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold TACC PF05010.9 CAR30868.1 - 0.0055 16.5 7.6 0.0063 16.3 5.2 1.1 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC) DUF4200 PF13863.1 CAR30868.1 - 0.091 12.7 11.7 0.064 13.2 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF544 PF04424.8 CAR30868.1 - 0.23 11.2 2.4 0.11 12.3 0.4 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF544) Syntaxin PF00804.20 CAR30868.1 - 3.9 7.6 8.0 2.1 8.5 0.5 2.2 1 1 1 2 2 2 0 Syntaxin Ribosomal_L32p PF01783.18 CAR30869.1 - 7.8e-09 35.5 8.9 1.8e-08 34.4 6.1 1.6 1 0 0 1 1 1 1 Ribosomal L32p protein family Papo_T_antigen PF02380.10 CAR30869.1 - 0.13 12.1 4.1 0.24 11.3 2.8 1.4 1 0 0 1 1 1 0 T-antigen specific domain Elongin_A PF06881.6 CAR30869.1 - 0.44 10.9 6.1 0.14 12.5 2.3 1.6 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A zf-FPG_IleRS PF06827.9 CAR30869.1 - 2.2 8.0 8.1 5.2 6.8 5.6 1.7 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS Septin PF00735.13 CAR30870.1 - 9.6e-108 359.4 1.0 1.1e-107 359.2 0.7 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 CAR30870.1 - 6.4e-09 35.7 0.4 1.1e-08 35.0 0.3 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 CAR30870.1 - 4.2e-07 29.2 0.4 8.5e-07 28.2 0.2 1.5 1 1 0 1 1 1 1 AIG1 family DUF258 PF03193.11 CAR30870.1 - 4.8e-07 29.1 0.1 9e-07 28.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 CAR30870.1 - 2.1e-06 27.3 0.9 8.9e-05 22.0 0.3 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CAR30870.1 - 3.7e-05 23.6 1.2 0.034 13.9 0.4 2.5 1 1 1 2 2 2 2 Dynamin family AAA_22 PF13401.1 CAR30870.1 - 0.00081 19.5 0.2 0.0054 16.8 0.0 2.0 1 1 1 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 CAR30870.1 - 0.00082 18.8 0.1 0.0022 17.4 0.0 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_16 PF13191.1 CAR30870.1 - 0.00083 19.3 0.1 0.0017 18.3 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.1 CAR30870.1 - 0.0012 18.5 0.1 0.0023 17.5 0.0 1.5 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 CAR30870.1 - 0.0013 18.5 0.6 0.035 13.9 0.9 2.8 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.22 CAR30870.1 - 0.0017 18.6 0.7 0.0037 17.5 0.5 1.7 1 1 0 1 1 1 1 ABC transporter Miro PF08477.8 CAR30870.1 - 0.0032 17.9 0.0 0.0093 16.4 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_10 PF12846.2 CAR30870.1 - 0.0036 16.8 0.5 0.0058 16.1 0.2 1.4 1 1 0 1 1 1 1 AAA-like domain AAA_23 PF13476.1 CAR30870.1 - 0.0054 17.0 0.1 0.0082 16.4 0.1 1.3 1 0 0 1 1 1 1 AAA domain IIGP PF05049.8 CAR30870.1 - 0.0065 15.3 0.0 0.01 14.7 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_14 PF13173.1 CAR30870.1 - 0.01 15.7 0.2 0.032 14.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 CAR30870.1 - 0.01 14.7 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.1 CAR30870.1 - 0.014 14.9 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 CAR30870.1 - 0.014 15.0 0.2 0.059 13.0 0.1 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Gtr1_RagA PF04670.7 CAR30870.1 - 0.021 13.9 1.5 0.16 11.1 1.0 2.1 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region ArgK PF03308.11 CAR30870.1 - 0.022 13.5 0.1 0.17 10.6 0.0 2.1 2 0 0 2 2 2 0 ArgK protein FeoB_N PF02421.13 CAR30870.1 - 0.044 13.0 0.6 2.1 7.6 0.4 2.5 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.4 CAR30870.1 - 0.088 12.2 0.4 1.3 8.5 0.1 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation eRF1_2 PF03464.10 CAR30871.1 - 1.2e-32 113.0 0.8 1.2e-32 113.0 0.6 1.8 2 0 0 2 2 2 1 eRF1 domain 2 eRF1_3 PF03465.10 CAR30871.1 - 1e-23 83.7 0.0 2.6e-23 82.4 0.0 1.7 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 CAR30871.1 - 1.2e-12 47.5 0.8 2.2e-12 46.6 0.5 1.5 1 0 0 1 1 1 1 eRF1 domain 1 HupH_C PF04809.8 CAR30871.1 - 0.032 13.9 0.0 0.073 12.8 0.0 1.6 1 0 0 1 1 1 0 HupH hydrogenase expression protein, C-terminal conserved region Rer1 PF03248.8 CAR30872.1 - 1.2e-68 230.1 6.9 1.3e-68 230.0 4.8 1.0 1 0 0 1 1 1 1 Rer1 family DUF2208 PF09973.4 CAR30872.1 - 0.26 10.4 5.2 0.049 12.8 0.7 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) PQ-loop PF04193.9 CAR30873.1 - 5.1e-05 22.7 16.9 0.00089 18.7 1.9 3.8 3 1 0 3 3 3 2 PQ loop repeat DUF161 PF02588.10 CAR30873.1 - 2 8.7 6.8 1.1 9.5 2.0 2.5 2 1 0 2 2 2 0 Uncharacterized BCR, YitT family COG1284 PLDc_2 PF13091.1 CAR30874.1 - 5.8e-16 58.3 0.0 4.7e-07 29.5 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 CAR30874.1 - 1.9e-10 40.2 0.1 2.6e-05 23.8 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif RE_NgoFVII PF09565.5 CAR30874.1 - 0.0021 17.0 0.0 0.57 9.0 0.0 2.2 2 0 0 2 2 2 2 NgoFVII restriction endonuclease UEV PF05743.8 CAR30876.1 - 8e-27 93.3 0.0 1.4e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 CAR30876.1 - 3.2e-22 77.9 0.2 7.7e-22 76.6 0.1 1.7 1 0 0 1 1 1 1 Vps23 core domain DKCLD PF08068.7 CAR30877.1 - 3.7e-28 97.2 0.1 1.6e-27 95.1 0.1 2.1 2 0 0 2 2 2 1 DKCLD (NUC011) domain PUA PF01472.15 CAR30877.1 - 4e-20 71.3 1.3 7.7e-20 70.3 0.9 1.5 1 0 0 1 1 1 1 PUA domain TruB_N PF01509.13 CAR30877.1 - 5.8e-20 71.9 0.1 5.8e-20 71.9 0.0 4.0 2 2 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) CDC27 PF09507.5 CAR30877.1 - 3.9 6.5 51.0 5 6.2 35.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MIP-T3 PF10243.4 CAR30877.1 - 7.4 4.9 61.3 9.5 4.5 42.5 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DnaJ PF00226.26 CAR30878.1 - 2.6e-23 81.5 1.2 4e-23 80.9 0.8 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CAR30878.1 - 2.4e-22 78.6 0.4 6.6e-19 67.5 0.0 2.5 2 1 0 2 2 2 2 DnaJ C terminal domain WD40 PF00400.27 CAR30879.1 - 3.6e-48 159.8 11.9 3.5e-12 45.6 0.0 7.5 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 CAR30879.1 - 1.5e-10 39.8 11.5 0.0091 14.1 0.6 4.9 2 1 2 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CAR30879.1 - 7.7e-06 24.9 0.9 0.31 9.7 0.0 3.6 1 1 1 2 2 2 2 Nup133 N terminal like DUF3312 PF11768.3 CAR30879.1 - 0.00028 19.2 0.0 0.00087 17.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) Hira PF07569.6 CAR30879.1 - 0.00078 18.7 0.1 2.1 7.5 0.0 4.0 2 1 2 4 4 4 1 TUP1-like enhancer of split Cytochrom_D1 PF02239.11 CAR30879.1 - 0.0018 16.6 0.0 0.081 11.2 0.0 2.1 1 1 0 2 2 2 1 Cytochrome D1 heme domain Nbas_N PF15492.1 CAR30879.1 - 0.0028 16.8 0.4 2 7.4 0.1 3.2 2 1 0 3 3 3 2 Neuroblastoma-amplified sequence, N terminal CPSF_A PF03178.10 CAR30879.1 - 0.026 13.6 0.0 1.2 8.1 0.0 2.3 2 1 0 2 2 2 0 CPSF A subunit region Coatomer_WDAD PF04053.9 CAR30879.1 - 0.054 12.2 0.0 0.24 10.1 0.0 1.7 1 1 0 2 2 2 0 Coatomer WD associated region RFX_DNA_binding PF02257.10 CAR30880.1 - 6.8e-32 109.4 0.1 6.8e-32 109.4 0.0 2.4 2 1 0 2 2 2 1 RFX DNA-binding domain Pox_D5 PF03288.11 CAR30880.1 - 0.023 14.9 0.0 0.1 12.8 0.0 2.1 2 0 0 2 2 2 0 Poxvirus D5 protein-like SR-25 PF10500.4 CAR30880.1 - 2.2 7.6 6.2 0.58 9.5 0.3 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Ribosomal_L30 PF00327.15 CAR30881.1 - 1.7e-13 49.9 0.5 5.3e-13 48.3 0.3 1.9 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e HALZ PF02183.13 CAR30882.1 - 0.00085 18.9 0.7 0.00085 18.9 0.5 8.9 7 2 1 9 9 9 3 Homeobox associated leucine zipper GAS PF13851.1 CAR30882.1 - 0.06 12.5 72.7 0.0085 15.3 13.7 4.9 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding Filament PF00038.16 CAR30882.1 - 0.15 11.5 55.7 0.17 11.3 6.7 4.5 1 1 2 3 3 3 0 Intermediate filament protein Reo_sigmaC PF04582.7 CAR30882.1 - 0.28 10.3 19.0 0.062 12.4 3.9 3.0 2 1 1 3 3 3 0 Reovirus sigma C capsid protein DivIC PF04977.10 CAR30882.1 - 0.49 9.9 0.0 0.33 10.4 2.0 8.6 5 2 4 9 9 9 0 Septum formation initiator TSC22 PF01166.13 CAR30882.1 - 3 7.8 22.1 0.069 13.1 0.8 6.0 2 2 5 7 7 7 0 TSC-22/dip/bun family bZIP_1 PF00170.16 CAR30882.1 - 3 7.8 41.7 0.93 9.4 0.2 7.8 5 2 5 10 10 10 0 bZIP transcription factor FlaC_arch PF05377.6 CAR30882.1 - 6.3 6.7 23.2 4.9 7.1 1.5 6.5 5 1 1 6 6 6 0 Flagella accessory protein C (FlaC) IncA PF04156.9 CAR30882.1 - 8.7 5.8 68.0 0.36 10.3 3.5 4.5 1 1 3 4 4 4 0 IncA protein GSIII_N PF12437.3 CAR30883.1 - 0.012 15.0 1.7 0.13 11.6 1.3 2.2 1 1 1 2 2 2 0 Glutamine synthetase type III N terminal MAS20 PF02064.10 CAR30883.1 - 8.1 6.3 7.5 17 5.3 5.2 1.6 1 1 0 1 1 1 0 MAS20 protein import receptor Iso_dh PF00180.15 CAR30885.1 - 4.5e-131 436.9 0.0 5.1e-131 436.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Aminotran_5 PF00266.14 CAR30886.1 - 2.3e-97 326.0 0.0 3.3e-97 325.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CAR30886.1 - 1.6e-09 37.3 0.0 2.5e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 CAR30886.1 - 3.4e-08 32.9 0.1 2.5e-07 30.0 0.0 2.2 2 1 1 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 CAR30886.1 - 8.8e-05 21.1 0.1 0.00014 20.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.15 CAR30886.1 - 0.0081 14.4 0.1 0.013 13.7 0.1 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Mito_carr PF00153.22 CAR30887.1 - 1.9e-53 178.1 3.7 8.4e-20 70.2 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF2036 PF09724.4 CAR30888.1 - 4.4e-80 269.2 0.0 5.1e-80 269.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) DUF3507 PF12015.3 CAR30889.1 - 1.6e-51 174.4 0.0 3.1e-51 173.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) DUF2015 PF09435.5 CAR30890.1 - 2.1e-37 127.7 0.0 2.2e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) RRM_1 PF00076.17 CAR30891.1 - 1.8e-56 187.6 0.1 1.1e-19 69.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR30891.1 - 8.3e-35 118.5 0.0 2.2e-10 40.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR30891.1 - 1.4e-21 76.0 0.0 1.5e-08 34.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CAR30891.1 - 0.081 12.6 0.1 8.8 6.1 0.0 3.2 3 1 0 3 3 3 0 Limkain b1 DUF1325 PF07039.6 CAR30892.1 - 3.1e-34 117.3 0.0 5e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain Agenet PF05641.7 CAR30892.1 - 0.0053 16.8 0.3 0.058 13.5 0.0 2.6 3 0 0 3 3 3 1 Agenet domain DUF4537 PF15057.1 CAR30892.1 - 0.039 13.7 0.0 0.094 12.4 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4537) PilZ PF07238.9 CAR30892.1 - 0.08 12.9 0.0 0.28 11.2 0.0 1.9 1 1 0 1 1 1 0 PilZ domain Suppressor_APC PF11414.3 CAR30892.1 - 0.082 12.6 0.2 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein DUF2360 PF10152.4 CAR30892.1 - 0.084 13.1 8.7 0.19 11.9 6.1 1.7 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Mucin PF01456.12 CAR30892.1 - 0.66 9.7 9.7 1.3 8.8 6.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein MCPVI PF02993.9 CAR30892.1 - 7.5 6.6 8.0 12 5.9 5.5 1.2 1 0 0 1 1 1 0 Minor capsid protein VI Ribosomal_L27 PF01016.14 CAR30893.1 - 3e-30 103.8 0.3 4.6e-30 103.2 0.2 1.3 1 0 0 1 1 1 1 Ribosomal L27 protein APG17 PF04108.7 CAR30893.1 - 0.0034 16.2 6.6 0.0051 15.6 4.6 1.2 1 0 0 1 1 1 1 Autophagy protein Apg17 ABC_membrane_3 PF13748.1 CAR30893.1 - 0.023 13.7 0.1 0.044 12.7 0.1 1.4 1 1 0 1 1 1 0 ABC transporter transmembrane region CemA PF03040.9 CAR30893.1 - 0.27 10.8 2.3 0.44 10.1 1.6 1.3 1 0 0 1 1 1 0 CemA family ALS_ss_C PF10369.4 CAR30894.1 - 1.5e-19 69.5 0.0 7.5e-19 67.2 0.0 2.1 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 CAR30894.1 - 7.8e-12 44.4 0.1 1.8e-11 43.2 0.1 1.7 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 CAR30894.1 - 5.8e-09 35.6 0.0 1.2e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 ACT domain Limkain-b1 PF11608.3 CAR30894.1 - 0.0032 17.1 0.0 0.021 14.5 0.0 2.2 2 0 0 2 2 2 1 Limkain b1 POM121 PF15229.1 CAR30894.1 - 0.2 11.0 2.5 0.32 10.3 1.7 1.2 1 0 0 1 1 1 0 POM121 family Iso_dh PF00180.15 CAR30895.1 - 3.3e-71 240.0 0.0 3.9e-71 239.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF3887 PF13026.1 CAR30895.1 - 0.057 13.7 1.6 1.6 9.0 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3887) HAD PF12710.2 CAR30896.1 - 2.9e-14 53.6 0.0 4e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 CAR30896.1 - 1.4e-07 30.9 0.0 1.9e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Putative Phosphatase HAD_2 PF13419.1 CAR30896.1 - 0.00094 19.4 0.0 0.016 15.4 0.0 2.8 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 CAR30896.1 - 0.016 14.4 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.21 CAR30896.1 - 0.091 13.1 0.1 1.5 9.1 0.0 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase UPF0052 PF01933.13 CAR30897.1 - 3.8e-68 230.0 0.0 5.7e-68 229.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 EF-hand_7 PF13499.1 CAR30898.1 - 1.7e-05 24.8 1.4 1.7e-05 24.8 1.0 2.3 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CAR30898.1 - 1.9e-05 24.1 1.2 0.13 12.1 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 CAR30898.1 - 0.00037 19.5 1.1 0.013 14.8 0.1 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 CAR30898.1 - 0.0075 15.8 0.8 0.56 9.8 0.2 2.7 2 0 0 2 2 2 1 EF-hand domain pair PLA2_B PF01735.13 CAR30899.1 - 1.8e-84 283.6 15.0 9.5e-68 228.5 5.1 3.4 2 1 0 2 2 2 2 Lysophospholipase catalytic domain Patatin PF01734.17 CAR30899.1 - 3.1e-05 23.9 0.0 9e-05 22.4 0.0 1.8 2 1 0 2 2 2 1 Patatin-like phospholipase SSV1_ORF_D-335 PF07935.6 CAR30899.1 - 0.043 13.5 0.4 8.4 6.2 0.0 2.6 2 1 1 3 3 3 0 ORF D-335-like protein ABC_tran PF00005.22 CAR30900.1 - 1.6e-44 151.5 0.2 5.7e-22 78.4 0.0 4.7 3 2 0 3 3 3 2 ABC transporter SMC_N PF02463.14 CAR30900.1 - 8.6e-17 61.0 0.0 6.5e-07 28.7 0.0 3.8 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CAR30900.1 - 9.3e-17 61.9 2.0 0.00068 19.6 0.0 4.6 4 1 0 5 5 4 4 AAA domain AAA_23 PF13476.1 CAR30900.1 - 4.8e-10 40.0 1.1 0.001 19.4 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 CAR30900.1 - 5.5e-10 38.6 0.0 0.0011 18.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CAR30900.1 - 1.4e-08 35.5 0.0 0.004 17.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 CAR30900.1 - 4.5e-08 32.4 0.1 0.00017 20.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 CAR30900.1 - 1.2e-07 31.8 0.0 0.0032 17.6 0.0 3.7 4 0 0 4 4 2 2 AAA domain AAA_28 PF13521.1 CAR30900.1 - 3.6e-07 30.2 0.0 0.0046 16.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 CAR30900.1 - 4.3e-07 29.6 0.0 0.12 11.7 0.0 3.9 4 0 0 4 4 4 2 AAA-like domain Dynamin_N PF00350.18 CAR30900.1 - 7.6e-07 29.0 0.0 6.7e-05 22.7 0.0 2.9 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 CAR30900.1 - 8.6e-07 28.9 0.0 0.0045 16.9 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_33 PF13671.1 CAR30900.1 - 1.1e-06 28.5 0.0 0.056 13.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain CLASP_N PF12348.3 CAR30900.1 - 1.1e-06 28.1 0.5 2e-05 24.0 0.3 2.2 1 1 1 2 2 2 2 CLASP N terminal AAA_18 PF13238.1 CAR30900.1 - 1.8e-06 28.2 0.1 0.04 14.2 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA PF00004.24 CAR30900.1 - 2.6e-06 27.6 0.0 0.45 10.7 0.0 4.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 CAR30900.1 - 4.2e-06 27.2 0.0 0.032 14.7 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein HEAT_2 PF13646.1 CAR30900.1 - 9.9e-06 25.7 2.2 0.011 16.0 1.0 2.9 1 1 1 2 2 2 2 HEAT repeats RNA_helicase PF00910.17 CAR30900.1 - 1.1e-05 25.4 0.0 0.2 11.8 0.0 3.0 2 0 0 2 2 2 2 RNA helicase SbcCD_C PF13558.1 CAR30900.1 - 1.2e-05 25.1 0.1 0.018 14.9 0.0 3.6 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit MobB PF03205.9 CAR30900.1 - 1.8e-05 24.4 0.0 0.3 10.7 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.1 CAR30900.1 - 3e-05 23.2 0.0 1.5 7.7 0.0 4.1 3 1 1 4 4 4 1 AAA ATPase domain ArgK PF03308.11 CAR30900.1 - 4e-05 22.5 0.1 0.12 11.1 0.0 2.6 2 0 0 2 2 2 2 ArgK protein Arch_ATPase PF01637.13 CAR30900.1 - 5.3e-05 23.0 0.0 0.44 10.1 0.0 2.9 2 0 0 2 2 2 2 Archaeal ATPase AAA_16 PF13191.1 CAR30900.1 - 5.9e-05 23.1 0.2 0.47 10.4 0.0 3.9 4 0 0 4 4 4 1 AAA ATPase domain ParcG PF10274.4 CAR30900.1 - 0.00021 21.2 0.3 1.3 8.9 0.0 3.2 2 1 1 3 3 3 1 Parkin co-regulated protein AAA_14 PF13173.1 CAR30900.1 - 0.00025 20.9 0.0 1.6 8.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 CAR30900.1 - 0.00036 20.2 0.3 0.16 11.6 0.0 2.7 3 0 0 3 3 2 1 NACHT domain DUF87 PF01935.12 CAR30900.1 - 0.00041 20.2 4.5 0.33 10.7 0.0 4.1 4 0 0 4 4 3 1 Domain of unknown function DUF87 MutS_V PF00488.16 CAR30900.1 - 0.00079 18.8 0.1 0.26 10.6 0.0 2.5 2 0 0 2 2 2 1 MutS domain V Adaptin_N PF01602.15 CAR30900.1 - 0.0027 16.1 4.0 0.004 15.5 2.0 1.7 1 1 1 2 2 2 1 Adaptin N terminal region PduV-EutP PF10662.4 CAR30900.1 - 0.0029 17.0 0.1 0.31 10.5 0.0 2.9 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation HEAT_EZ PF13513.1 CAR30900.1 - 0.003 17.9 6.0 0.33 11.4 0.2 4.3 5 1 1 6 6 2 1 HEAT-like repeat AAA_30 PF13604.1 CAR30900.1 - 0.003 17.1 0.1 5.4 6.5 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_13 PF13166.1 CAR30900.1 - 0.004 15.6 8.7 1.5 7.1 0.0 4.5 4 1 0 5 5 5 2 AAA domain AAA_25 PF13481.1 CAR30900.1 - 0.0042 16.5 0.0 1.2 8.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 CAR30900.1 - 0.0044 16.4 0.7 2.7 7.3 0.0 3.2 4 0 0 4 4 3 1 CobW/HypB/UreG, nucleotide-binding domain HEAT PF02985.17 CAR30900.1 - 0.0064 16.4 0.1 33 4.9 0.0 4.3 3 0 0 3 3 3 0 HEAT repeat T2SE PF00437.15 CAR30900.1 - 0.01 14.7 0.1 0.92 8.3 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 CAR30900.1 - 0.012 15.0 0.4 2 7.8 0.0 2.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family Mg_chelatase PF01078.16 CAR30900.1 - 0.019 14.1 0.0 1.2 8.3 0.0 2.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.12 CAR30900.1 - 0.025 14.0 0.2 8.1 5.8 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.13 CAR30900.1 - 0.027 13.5 0.3 1.2 8.0 0.0 2.8 3 0 0 3 3 3 0 Septin Rad17 PF03215.10 CAR30900.1 - 0.03 13.0 0.0 1 7.9 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 CAR30900.1 - 0.032 13.9 0.1 5.4 6.8 0.0 2.8 2 0 0 2 2 2 0 Part of AAA domain Cnd1 PF12717.2 CAR30900.1 - 0.037 13.8 0.3 0.5 10.1 0.0 2.8 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 UME PF08064.8 CAR30900.1 - 0.037 13.9 1.0 0.29 11.1 0.7 2.3 1 1 1 2 2 2 0 UME (NUC010) domain NTPase_1 PF03266.10 CAR30900.1 - 0.066 12.9 0.0 16 5.1 0.0 2.8 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.9 CAR30900.1 - 0.081 12.6 0.0 23 4.7 0.0 3.4 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) DUF3349 PF11829.3 CAR30900.1 - 0.56 10.6 2.9 0.93 9.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) DUF843 PF05814.6 CAR30900.1 - 1.9 8.3 4.5 79 3.1 0.0 3.1 3 0 0 3 3 3 0 Baculovirus protein of unknown function (DUF843) Pkinase PF00069.20 CAR30901.1 - 2.2e-56 190.9 0.0 4.1e-56 189.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR30901.1 - 4.8e-23 81.5 0.0 1.6e-22 79.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR30901.1 - 7.1e-08 31.7 0.1 0.0011 17.9 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 CAR30901.1 - 0.0017 17.4 0.0 0.003 16.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SNF2_N PF00176.18 CAR30902.1 - 1.1e-43 149.1 0.3 2.3e-43 148.1 0.2 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 CAR30902.1 - 6.8e-11 41.8 9.9 3.1e-10 39.6 6.9 2.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CAR30902.1 - 1.6e-09 37.2 11.0 5.3e-09 35.5 7.6 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CAR30902.1 - 5.5e-08 32.3 7.2 5.5e-08 32.3 5.0 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAR30902.1 - 1.4e-07 31.3 11.8 6.2e-07 29.3 8.2 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CAR30902.1 - 1.8e-05 24.5 9.1 5e-05 23.0 6.3 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 CAR30902.1 - 4.8e-05 22.9 11.0 4.8e-05 22.9 7.6 2.2 2 0 0 2 2 1 1 zinc-RING finger domain ResIII PF04851.10 CAR30902.1 - 5.8e-05 23.0 0.0 5.8e-05 23.0 0.0 2.9 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit zf-rbx1 PF12678.2 CAR30902.1 - 0.0001 22.3 10.9 0.00027 20.9 6.7 2.5 2 1 0 2 2 2 1 RING-H2 zinc finger Helicase_C PF00271.26 CAR30902.1 - 0.0061 16.4 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-P11 PF03854.9 CAR30902.1 - 0.013 14.9 6.7 0.051 13.0 4.6 2.0 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_UBOX PF13445.1 CAR30902.1 - 0.015 15.0 8.0 0.056 13.1 5.5 2.1 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.1 CAR30902.1 - 0.037 13.8 1.7 0.11 12.2 1.2 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 CAR30902.1 - 0.044 13.3 5.9 0.11 12.0 4.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-UDP PF14569.1 CAR30902.1 - 0.074 12.7 2.2 0.13 12.0 0.7 2.0 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-RING_4 PF14570.1 CAR30902.1 - 0.1 12.1 7.5 0.28 10.8 5.2 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 CAR30902.1 - 0.31 10.9 6.0 0.2 11.5 2.4 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Clat_adaptor_s PF01217.15 CAR30904.1 - 6.1e-55 184.8 0.0 7e-55 184.6 0.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TP_methylase PF00590.15 CAR30905.1 - 1.8e-23 83.3 0.0 2.8e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF4434 PF14488.1 CAR30905.1 - 0.0081 15.8 0.0 0.03 14.0 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4434) Pec_lyase_C PF00544.14 CAR30906.1 - 0.003 17.0 0.2 0.069 12.6 0.0 2.3 2 0 0 2 2 2 2 Pectate lyase ABC1 PF03109.11 CAR30908.1 - 2.6e-31 108.0 0.0 5.1e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 CAR30908.1 - 0.00059 19.2 0.0 0.004 16.5 0.0 2.1 2 0 0 2 2 2 1 RIO1 family HTH_OrfB_IS605 PF12323.3 CAR30908.1 - 1.3 8.4 5.8 0.17 11.2 0.8 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain DUF904 PF06005.7 CAR30909.1 - 0.00038 20.6 15.2 0.032 14.5 0.7 2.9 1 1 1 2 2 2 2 Protein of unknown function (DUF904) bZIP_1 PF00170.16 CAR30909.1 - 0.0012 18.7 0.8 0.0012 18.7 0.6 2.9 2 1 1 3 3 3 1 bZIP transcription factor Phlebovirus_NSM PF07246.6 CAR30909.1 - 0.0069 15.5 1.7 0.0069 15.5 1.2 1.4 1 1 0 1 1 1 1 Phlebovirus nonstructural protein NS-M Tropomyosin_1 PF12718.2 CAR30909.1 - 0.0081 16.0 15.7 0.025 14.4 10.9 1.8 1 1 0 1 1 1 1 Tropomyosin like ATG16 PF08614.6 CAR30909.1 - 0.0092 15.8 5.5 0.0092 15.8 3.8 2.1 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.7 CAR30909.1 - 0.011 15.5 5.4 0.011 15.5 3.8 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein bZIP_2 PF07716.10 CAR30909.1 - 0.015 15.0 2.7 0.015 15.0 1.9 3.8 3 2 0 3 3 3 0 Basic region leucine zipper TMCO5 PF14992.1 CAR30909.1 - 0.055 12.5 10.1 0.065 12.3 7.0 1.2 1 0 0 1 1 1 0 TMCO5 family DUF972 PF06156.8 CAR30909.1 - 0.086 13.1 12.1 0.049 13.9 3.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Tropomyosin PF00261.15 CAR30909.1 - 0.11 11.5 13.3 0.18 10.8 9.2 1.4 1 0 0 1 1 1 0 Tropomyosin MbeD_MobD PF04899.7 CAR30909.1 - 0.16 11.8 3.9 0.1 12.5 0.5 2.4 2 1 1 3 3 3 0 MbeD/MobD like FlaC_arch PF05377.6 CAR30909.1 - 0.22 11.4 5.8 4 7.3 0.3 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) YlqD PF11068.3 CAR30909.1 - 0.22 11.5 4.7 0.14 12.2 1.9 1.6 1 1 1 2 2 2 0 YlqD protein MCC-bdg_PDZ PF10506.4 CAR30909.1 - 0.24 11.2 5.0 6.7 6.6 0.3 2.7 3 0 0 3 3 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome APG6 PF04111.7 CAR30909.1 - 0.36 9.8 9.9 0.43 9.5 6.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Gal4_dimer PF03902.8 CAR30909.1 - 0.45 10.4 4.7 0.15 12.0 0.5 2.3 3 0 0 3 3 2 0 Gal4-like dimerisation domain IncA PF04156.9 CAR30909.1 - 0.47 10.0 16.5 17 4.9 11.4 2.1 1 1 0 1 1 1 0 IncA protein DUF641 PF04859.7 CAR30909.1 - 0.86 9.3 6.1 6.2 6.5 0.3 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF4404 PF14357.1 CAR30909.1 - 1 9.8 5.7 0.38 11.2 1.3 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4404) TMF_DNA_bd PF12329.3 CAR30909.1 - 1.2 8.9 9.7 5.5 6.8 0.8 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.5 CAR30909.1 - 1.3 9.1 6.4 0.47 10.5 2.5 1.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TSC22 PF01166.13 CAR30909.1 - 3.9 7.4 9.2 0.43 10.5 0.5 3.0 1 1 2 3 3 3 0 TSC-22/dip/bun family V_ATPase_I PF01496.14 CAR30909.1 - 5.7 4.6 9.8 9.9 3.8 6.7 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Prefoldin PF02996.12 CAR30909.1 - 6 6.5 9.6 13 5.4 0.1 3.1 1 1 1 3 3 3 0 Prefoldin subunit SlyX PF04102.7 CAR30909.1 - 6.3 7.2 8.1 6.9 7.1 1.3 2.5 1 1 1 2 2 2 0 SlyX DMPK_coil PF08826.5 CAR30909.1 - 7 6.6 11.5 0.29 11.0 0.5 3.1 2 1 1 3 3 3 0 DMPK coiled coil domain like ACCA PF03255.9 CAR30909.1 - 7.7 6.0 7.1 2.6 7.5 0.8 2.4 1 1 2 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit OCD_Mu_crystall PF02423.10 CAR30910.1 - 2.7e-08 32.9 0.0 7.9e-08 31.4 0.0 1.6 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Fungal_trans PF04082.13 CAR30911.1 - 3.7e-08 32.5 2.3 5e-07 28.8 0.0 2.7 3 0 0 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR30911.1 - 9.9e-08 31.7 9.1 2.1e-07 30.6 6.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain G_glu_transpept PF01019.16 CAR30912.1 - 4.4e-123 411.4 0.0 5.1e-123 411.2 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Ferric_reduct PF01794.14 CAR30913.1 - 1.5e-20 73.5 7.3 1.5e-20 73.5 5.1 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 CAR30913.1 - 6.1e-12 45.7 0.0 9.1e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 CAR30913.1 - 9.7e-09 35.0 0.1 2.1e-08 33.9 0.1 1.5 1 0 0 1 1 1 1 FAD-binding domain Cytochrom_B_N PF00033.14 CAR30913.1 - 0.27 10.5 11.3 2.1 7.6 2.3 2.6 2 1 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB DUF2417 PF10329.4 CAR30913.1 - 0.45 9.8 9.2 0.044 13.1 3.2 1.6 2 0 0 2 2 2 0 Region of unknown function (DUF2417) SH3BGR PF04908.10 CAR30915.1 - 0.055 13.4 0.0 0.055 13.4 0.0 4.3 4 1 1 5 5 5 0 SH3-binding, glutamic acid-rich protein HTH_AraC PF00165.18 CAR30916.1 - 0.09 12.6 0.0 0.35 10.7 0.0 2.0 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family Glycogen_syn PF05693.8 CAR30917.1 - 0 1086.6 0.0 0 1086.4 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 CAR30917.1 - 4.7e-10 39.1 0.0 1.7e-06 27.5 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CAR30917.1 - 2.3e-05 24.5 0.2 4.8e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Pkinase PF00069.20 CAR30918.1 - 4.2e-71 239.1 0.0 6e-71 238.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR30918.1 - 1.6e-40 138.8 0.0 3.7e-40 137.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR30918.1 - 0.00027 20.0 0.1 0.0024 16.9 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 CAR30918.1 - 0.0082 15.2 0.0 0.053 12.5 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CAR30918.1 - 0.024 13.9 0.0 0.05 12.9 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 CAR30918.1 - 0.033 12.9 0.1 0.057 12.1 0.1 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase WHIM1 PF15612.1 CAR30919.1 - 0.00089 19.0 0.0 0.003 17.4 0.0 2.0 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 zf-RING_2 PF13639.1 CAR30920.1 - 1.6e-10 40.5 5.8 3.4e-10 39.5 4.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CAR30920.1 - 3.9e-09 36.5 2.9 7.4e-09 35.6 2.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CAR30920.1 - 5.3e-08 32.4 3.9 9.2e-08 31.6 2.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CAR30920.1 - 7.7e-07 28.6 4.1 1.6e-06 27.6 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CAR30920.1 - 1.7e-05 24.3 6.4 3.4e-05 23.4 4.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAR30920.1 - 4.9e-05 23.2 5.6 0.00026 20.9 3.9 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CAR30920.1 - 0.0011 18.8 1.7 0.0021 17.8 1.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 CAR30920.1 - 0.0017 18.2 3.3 0.0051 16.7 2.3 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_UBOX PF13445.1 CAR30920.1 - 0.013 15.1 0.4 0.035 13.8 0.2 1.7 1 0 0 1 1 1 0 RING-type zinc-finger RINGv PF12906.2 CAR30920.1 - 1.9 8.5 5.2 5.2 7.1 3.6 1.8 1 1 0 1 1 1 0 RING-variant domain UDPGP PF01704.13 CAR30921.1 - 1.4e-188 626.6 0.0 1.7e-188 626.4 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Zn_clus PF00172.13 CAR30922.1 - 8.7e-09 35.1 11.5 1.6e-08 34.3 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OTU PF02338.14 CAR30923.1 - 4.7e-21 75.5 1.7 7.1e-21 75.0 0.0 2.0 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 CAR30923.1 - 1.3e-05 24.6 5.5 1.9e-05 24.1 0.0 2.8 2 1 0 2 2 2 1 Peptidase C65 Otubain HMG_CoA_synt_C PF08540.5 CAR30923.1 - 0.1 12.0 1.6 0.19 11.1 1.1 1.4 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase C terminal DUF3447 PF11929.3 CAR30923.1 - 0.11 12.3 2.2 0.27 11.0 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3447) TATR PF03430.8 CAR30923.1 - 2.3 6.7 10.4 3 6.3 7.2 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Astro_capsid PF03115.9 CAR30923.1 - 2.8 6.0 12.1 3.4 5.7 8.4 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor YchF-GTPase_C PF06071.8 CAR30924.1 - 9.1e-33 111.9 0.0 2.1e-32 110.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 CAR30924.1 - 1.4e-12 47.5 0.0 2.5e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 CAR30924.1 - 5.1e-06 26.2 0.0 1.1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 CAR30924.1 - 0.00094 18.4 0.0 0.0017 17.6 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_14 PF13173.1 CAR30924.1 - 0.12 12.2 0.0 0.46 10.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain Ribosomal_S10 PF00338.17 CAR30925.1 - 7.8e-28 96.1 0.6 9.1e-28 95.9 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e YbbR PF07949.7 CAR30925.1 - 0.093 12.8 1.7 9.5 6.4 0.1 2.1 2 0 0 2 2 2 0 YbbR-like protein DUF4320 PF14208.1 CAR30925.1 - 0.11 12.4 0.1 0.26 11.2 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4320) DUF1688 PF07958.6 CAR30926.1 - 2e-163 543.7 0.0 2.3e-163 543.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Lung_7-TM_R PF06814.8 CAR30927.1 - 1.2e-82 277.2 24.7 1.5e-82 276.9 17.1 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor Nfu_N PF08712.6 CAR30928.1 - 3.1e-25 87.5 0.0 6.1e-25 86.6 0.0 1.5 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 CAR30928.1 - 4.3e-22 77.6 0.1 7.1e-22 76.9 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.4 CAR30928.1 - 0.012 15.4 0.8 0.024 14.4 0.5 1.5 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus Sigma70_r1_2 PF00140.15 CAR30928.1 - 0.062 12.9 0.1 0.16 11.6 0.1 1.7 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 Pterin_4a PF01329.14 CAR30929.1 - 8.9e-25 86.2 0.2 1.1e-24 86.0 0.2 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Adap_comp_sub PF00928.16 CAR30930.1 - 1.1e-60 204.9 0.3 1.4e-60 204.5 0.2 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family ADIP PF11559.3 CAR30931.1 - 0.02 14.7 1.9 0.045 13.6 1.3 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Tape_meas_lam_C PF09718.5 CAR30931.1 - 0.1 12.5 0.0 0.68 9.8 0.0 2.2 3 0 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF1700 PF08006.6 CAR30931.1 - 1 8.6 4.1 0.3 10.3 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) Opi1 PF08618.5 CAR30932.1 - 1.4e-29 103.3 13.5 5.8e-24 84.8 1.2 2.6 2 1 1 3 3 3 2 Transcription factor Opi1 DUF4611 PF15387.1 CAR30932.1 - 0.69 10.0 30.8 0.86 9.7 3.8 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Nop14 PF04147.7 CAR30932.1 - 1.7 6.4 30.4 0.039 11.9 9.7 2.2 2 0 0 2 2 2 0 Nop14-like family Snf7 PF03357.16 CAR30933.1 - 5e-31 107.3 17.3 5e-31 107.3 12.0 1.7 2 0 0 2 2 2 1 Snf7 PAS_7 PF12860.2 CAR30933.1 - 0.0051 16.8 4.3 0.36 10.8 0.0 2.9 2 1 2 4 4 4 2 PAS fold LAGLIDADG_2 PF03161.8 CAR30933.1 - 0.016 15.1 0.2 0.026 14.4 0.2 1.3 1 0 0 1 1 1 0 LAGLIDADG DNA endonuclease family Iron_permease PF04120.7 CAR30933.1 - 1.3 8.5 10.7 0.14 11.7 0.6 2.7 1 1 2 3 3 3 0 Low affinity iron permease PSD4 PF07631.6 CAR30933.1 - 1.7 8.9 5.8 0.75 10.1 0.2 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1592) CLU PF13236.1 CAR30934.1 - 1.9e-76 256.3 0.0 4e-76 255.2 0.0 1.6 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 CAR30934.1 - 5.3e-32 111.0 2.0 8.9e-23 81.0 0.0 3.7 4 0 0 4 4 4 2 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 CAR30934.1 - 2.4e-15 56.4 1.2 9.4e-15 54.5 0.1 2.7 3 0 0 3 3 3 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 CAR30934.1 - 7.7e-07 28.9 0.4 0.0083 16.0 0.0 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat BUD22 PF09073.5 CAR30936.1 - 1.4e-88 297.8 61.0 1.9e-88 297.3 42.3 1.3 1 0 0 1 1 1 1 BUD22 p450 PF00067.17 CAR30937.1 - 2.1e-55 188.1 0.1 2.7e-55 187.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Spc42p PF11544.3 CAR30938.1 - 1.7e-26 91.9 2.8 1.7e-26 91.9 2.0 2.6 3 0 0 3 3 3 1 Spindle pole body component Spc42p DivIVA PF05103.8 CAR30938.1 - 0.9 9.6 5.2 3.1 7.8 0.2 2.4 2 1 0 2 2 2 0 DivIVA protein Uds1 PF15456.1 CAR30938.1 - 2 8.4 8.1 6.9 6.6 0.8 2.3 2 0 0 2 2 2 0 Up-regulated During Septation KilA-N PF04383.8 CAR30939.1 - 0.0018 17.8 0.0 0.0064 16.0 0.0 1.8 1 1 0 1 1 1 1 KilA-N domain Fungal_trans PF04082.13 CAR30940.1 - 1.7e-17 63.1 13.3 1.7e-17 63.1 9.2 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR30940.1 - 4.6e-09 36.0 12.1 4.6e-09 36.0 8.4 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_primase_lrg PF04104.9 CAR30941.1 - 2.6e-81 272.7 0.8 5.3e-81 271.7 0.1 1.8 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit Rep_trans PF02486.14 CAR30941.1 - 0.047 13.1 0.1 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 Replication initiation factor DASH_Dad4 PF08650.5 CAR30941.1 - 0.33 10.8 2.2 1.9 8.4 0.2 2.8 3 0 0 3 3 3 0 DASH complex subunit Dad4 Amino_oxidase PF01593.19 CAR30942.1 - 1.2e-63 215.7 0.1 3.4e-62 211.0 0.1 2.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CAR30942.1 - 1e-12 47.8 0.4 2.1e-12 46.8 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CAR30942.1 - 3.7e-08 33.6 0.1 7e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CAR30942.1 - 2.9e-06 26.4 0.1 3.6e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CAR30942.1 - 3.7e-05 22.7 0.3 5.9e-05 22.0 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 CAR30942.1 - 0.00036 19.6 0.2 0.00059 19.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 CAR30942.1 - 0.0019 17.3 0.3 0.0033 16.5 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 CAR30942.1 - 0.0077 16.6 0.5 0.017 15.5 0.4 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CAR30942.1 - 0.0079 14.7 0.4 0.037 12.4 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 CAR30942.1 - 0.017 15.0 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CAR30942.1 - 0.025 13.4 0.3 0.048 12.5 0.2 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 CAR30942.1 - 0.027 14.5 0.2 0.048 13.7 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 CAR30942.1 - 0.049 13.0 0.2 0.09 12.1 0.1 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_7 PF13241.1 CAR30942.1 - 0.07 13.3 0.1 0.26 11.5 0.0 2.0 3 0 0 3 3 2 0 Putative NAD(P)-binding FMO-like PF00743.14 CAR30942.1 - 0.15 10.2 0.1 0.23 9.6 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Copper-fist PF00649.13 CAR30943.1 - 4.8e-20 70.4 4.9 4.8e-20 70.4 3.4 2.2 2 0 0 2 2 2 1 Copper fist DNA binding domain UQ_con PF00179.21 CAR30944.1 - 4.1e-49 165.6 0.0 4.6e-49 165.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CAR30944.1 - 0.033 14.0 1.2 0.07 13.0 0.8 1.8 1 1 0 1 1 1 0 RWD domain Prok-E2_B PF14461.1 CAR30944.1 - 0.14 11.8 0.1 0.22 11.2 0.1 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family B Glyco_hydro_76 PF03663.9 CAR30945.1 - 2.5e-144 481.2 24.4 3.1e-144 480.9 16.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF2347 PF09804.4 CAR30946.1 - 1e-72 244.7 0.0 1.7e-72 244.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 CAR30946.1 - 1.7e-16 60.7 5.5 2.5e-07 30.9 0.7 3.6 2 1 1 3 3 3 2 Domain of unknown function (DUF4484) Avl9 PF09794.4 CAR30946.1 - 3.4e-05 22.5 0.0 0.002 16.7 0.0 2.9 2 1 0 2 2 2 1 Transport protein Avl9 SPA PF08616.5 CAR30946.1 - 0.0056 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis DUF2303 PF10065.4 CAR30947.1 - 0.00036 19.5 0.2 0.00041 19.3 0.2 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2303) Spectrin PF00435.16 CAR30947.1 - 0.019 15.2 4.4 0.033 14.4 3.1 1.4 1 0 0 1 1 1 0 Spectrin repeat Hrs_helical PF12210.3 CAR30947.1 - 0.032 14.4 2.6 0.041 14.1 1.7 1.5 1 1 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF1986 PF09342.6 CAR30947.1 - 0.041 13.1 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) BLOC1_2 PF10046.4 CAR30947.1 - 0.12 12.5 5.8 0.22 11.6 4.0 1.5 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4463 PF14703.1 CAR30947.1 - 0.29 11.6 4.1 1.3 9.5 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4463) EMP24_GP25L PF01105.19 CAR30947.1 - 0.44 10.2 2.9 0.45 10.1 2.0 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF848 PF05852.6 CAR30947.1 - 0.57 10.0 7.1 0.56 10.0 3.8 1.8 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) AAA_23 PF13476.1 CAR30947.1 - 0.65 10.2 8.0 0.79 10.0 5.5 1.1 1 0 0 1 1 1 0 AAA domain TrmE_N PF10396.4 CAR30948.1 - 1.1e-34 118.7 0.0 2.4e-34 117.6 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.18 CAR30948.1 - 3.2e-24 85.1 0.7 8.4e-24 83.7 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTPase_Cys_C PF12631.2 CAR30948.1 - 1.5e-15 57.3 0.0 7.1e-15 55.1 0.0 2.2 2 0 0 2 2 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE FeoB_N PF02421.13 CAR30948.1 - 9.1e-15 54.2 0.3 2e-14 53.1 0.2 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 CAR30948.1 - 4.8e-10 39.1 0.2 1.2e-08 34.6 0.1 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CAR30948.1 - 7.9e-08 32.2 3.9 0.00068 19.4 0.1 3.0 2 1 1 3 3 3 2 Dynamin family Ras PF00071.17 CAR30948.1 - 1.6e-07 30.8 0.0 4.6e-07 29.3 0.0 1.8 1 1 0 1 1 1 1 Ras family Arf PF00025.16 CAR30948.1 - 2.4e-07 30.1 1.3 0.0048 16.1 0.0 2.5 3 0 0 3 3 3 2 ADP-ribosylation factor family AIG1 PF04548.11 CAR30948.1 - 5.5e-06 25.6 0.7 2e-05 23.7 0.5 1.9 1 1 0 1 1 1 1 AIG1 family Miro PF08477.8 CAR30948.1 - 8.4e-06 26.2 0.1 5.6e-05 23.6 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein DUF258 PF03193.11 CAR30948.1 - 7.5e-05 21.9 0.4 0.00019 20.6 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 CAR30948.1 - 0.00049 19.5 0.0 0.068 12.6 0.0 2.5 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 CAR30948.1 - 0.0009 19.0 0.5 0.04 13.6 0.1 2.7 1 1 1 2 2 2 1 Archaeal ATPase ArgK PF03308.11 CAR30948.1 - 0.0026 16.5 0.0 0.11 11.2 0.0 2.4 2 0 0 2 2 2 1 ArgK protein AAA_25 PF13481.1 CAR30948.1 - 0.0034 16.7 0.1 4.1 6.7 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CAR30948.1 - 0.0052 16.9 0.0 0.028 14.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain Septin PF00735.13 CAR30948.1 - 0.013 14.4 0.7 4.1 6.3 0.2 2.4 2 0 0 2 2 2 0 Septin SRPRB PF09439.5 CAR30948.1 - 0.018 14.2 0.5 0.054 12.6 0.3 1.9 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit cobW PF02492.14 CAR30948.1 - 0.02 14.3 0.4 2.3 7.6 0.1 2.4 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 CAR30948.1 - 0.023 14.9 0.5 0.064 13.5 0.3 1.9 1 1 0 1 1 1 0 ABC transporter DUF573 PF04504.9 CAR30948.1 - 0.029 14.6 0.9 0.086 13.1 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF573 AAA_16 PF13191.1 CAR30948.1 - 0.041 13.8 0.0 0.44 10.5 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain eIF-5a PF01287.15 CAR30948.1 - 0.042 13.7 0.3 1 9.3 0.1 2.7 2 0 0 2 2 2 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Gtr1_RagA PF04670.7 CAR30948.1 - 0.049 12.7 3.1 0.26 10.3 0.2 2.6 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_24 PF13479.1 CAR30948.1 - 0.05 13.1 0.0 0.094 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 CAR30948.1 - 0.067 12.7 0.2 3.3 7.1 0.1 3.2 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein PPV_E1_C PF00519.12 CAR30948.1 - 0.081 11.5 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase AAA_28 PF13521.1 CAR30948.1 - 0.089 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ribonuclease_3 PF00636.21 CAR30949.1 - 4.2e-08 33.6 0.1 1.6e-07 31.7 0.0 2.0 2 0 0 2 2 2 1 Ribonuclease III domain dsrm PF00035.20 CAR30949.1 - 2.3e-07 31.2 0.0 5.6e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif Prefoldin_2 PF01920.15 CAR30950.1 - 0.02 14.6 1.0 0.038 13.7 0.2 1.7 2 0 0 2 2 2 0 Prefoldin subunit Peptidase_C34 PF05413.6 CAR30950.1 - 0.07 13.1 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative closterovirus papain-like endopeptidase DUF3802 PF12290.3 CAR30950.1 - 0.51 10.6 2.8 0.85 9.9 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3802) Pex2_Pex12 PF04757.9 CAR30951.1 - 2.8e-39 134.8 6.9 3.5e-39 134.5 4.8 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 CAR30951.1 - 6.1e-06 26.1 5.1 1e-05 25.4 3.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CAR30951.1 - 1.4e-05 24.6 2.9 2.3e-05 23.9 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CAR30951.1 - 0.012 15.4 5.1 0.021 14.6 3.5 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.20 CAR30951.1 - 0.11 12.1 5.8 0.2 11.3 4.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CAR30951.1 - 0.48 10.3 5.7 0.85 9.5 4.0 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Rad50_zn_hook PF04423.9 CAR30951.1 - 2.2 7.8 4.0 27 4.3 0.2 3.1 3 0 0 3 3 3 0 Rad50 zinc hook motif F_bP_aldolase PF01116.15 CAR30952.1 - 3.1e-94 315.2 0.0 3.5e-94 315.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DUF89 PF01937.14 CAR30953.1 - 1.8e-117 392.1 1.3 2e-117 391.9 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 DWNN PF08783.6 CAR30954.1 - 2.1e-34 117.2 1.3 1.4e-33 114.6 0.1 2.2 2 0 0 2 2 2 1 DWNN domain zf-Nse PF11789.3 CAR30954.1 - 2.8e-05 23.5 0.5 6.9e-05 22.2 0.4 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-CCHC_2 PF13696.1 CAR30954.1 - 0.0012 18.2 6.1 0.0017 17.7 3.0 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.18 CAR30954.1 - 0.0024 17.7 2.7 0.0024 17.7 1.9 3.3 4 0 0 4 4 4 1 Zinc knuckle U-box PF04564.10 CAR30954.1 - 0.0089 15.9 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 U-box domain Zn_Tnp_IS1595 PF12760.2 CAR30954.1 - 0.021 14.6 0.4 1 9.2 0.0 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Rubredoxin PF00301.15 CAR30954.1 - 0.031 14.1 8.2 0.79 9.6 0.2 3.3 3 0 0 3 3 3 0 Rubredoxin zf-CCHC_5 PF14787.1 CAR30954.1 - 0.046 13.2 0.6 0.13 11.7 0.4 1.8 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.1 CAR30954.1 - 0.061 13.0 0.1 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle TFIIA_gamma_C PF02751.9 CAR30955.1 - 2e-27 94.7 0.1 2.9e-27 94.2 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 CAR30955.1 - 1.2e-24 85.5 0.1 1.6e-24 85.1 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TAP42 PF04177.7 CAR30956.1 - 4.6e-91 305.2 23.1 5.2e-91 305.1 16.0 1.0 1 0 0 1 1 1 1 TAP42-like family Pox_A22 PF04848.8 CAR30956.1 - 0.35 10.7 3.0 0.19 11.6 0.2 2.0 2 0 0 2 2 2 0 Poxvirus A22 protein Striatin PF08232.7 CAR30958.1 - 1.8e-23 83.3 13.6 5.7e-21 75.2 9.4 3.5 1 1 0 1 1 1 1 Striatin family TCTP PF00838.12 CAR30959.1 - 4e-70 235.0 0.7 4.5e-70 234.9 0.5 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein adh_short PF00106.20 CAR30960.1 - 1.3e-15 57.7 0.2 4.2e-08 33.2 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 CAR30960.1 - 9e-12 45.2 4.5 3.7e-11 43.2 3.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CAR30960.1 - 0.0001 21.8 0.1 0.23 10.8 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.5 CAR30960.1 - 0.0034 17.0 0.5 0.8 9.3 0.2 2.8 2 2 0 2 2 2 2 KR domain NAD_binding_4 PF07993.7 CAR30960.1 - 0.026 13.4 0.8 1.8 7.4 0.3 2.9 2 1 0 2 2 2 0 Male sterility protein TrwC PF08751.6 CAR30960.1 - 0.052 12.9 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 TrwC relaxase Polysacc_synt_2 PF02719.10 CAR30960.1 - 0.073 11.9 0.7 0.7 8.7 0.1 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 CAR30960.1 - 0.076 13.0 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding CUE PF02845.11 CAR30961.1 - 0.0015 17.9 0.1 0.0037 16.7 0.0 1.7 1 0 0 1 1 1 1 CUE domain UPF0203 PF05254.7 CAR30962.1 - 4.9e-30 103.1 4.1 5.7e-30 102.9 2.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 CAR30962.1 - 0.023 14.4 3.8 0.31 10.8 0.3 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.11 CAR30962.1 - 0.027 14.4 4.2 0.084 12.8 2.9 1.7 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein COX6B PF02297.12 CAR30962.1 - 0.13 12.2 6.2 2.9 7.9 0.2 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 CAR30962.1 - 1 9.4 3.2 32 4.6 2.5 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Lipid_DES PF08557.5 CAR30963.1 - 1.6e-20 71.9 0.2 2.9e-20 71.1 0.2 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) FA_desaturase PF00487.19 CAR30963.1 - 1e-19 71.0 18.2 1.9e-11 43.9 5.3 2.2 2 0 0 2 2 2 2 Fatty acid desaturase DUF3317 PF11779.3 CAR30965.1 - 0.018 14.4 3.7 0.026 13.9 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3317) Pkinase PF00069.20 CAR30966.1 - 6.1e-35 120.6 0.0 1e-34 119.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR30966.1 - 1.1e-22 80.3 0.0 1.6e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CAR30966.1 - 0.0019 17.9 0.6 0.4 10.3 0.0 2.8 3 0 0 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 CAR30966.1 - 0.023 13.6 0.0 0.037 12.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like ORC2 PF04084.9 CAR30967.1 - 1.3e-110 369.2 0.1 1.8e-110 368.8 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 PBP1_TM PF14812.1 CAR30967.1 - 7 7.0 12.8 16 5.8 8.9 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal tRNA-synt_2 PF00152.15 CAR30968.1 - 9.6e-89 297.4 0.5 1.4e-88 296.9 0.3 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CAR30968.1 - 6e-13 48.4 0.0 2.4e-12 46.5 0.0 2.0 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CAR30968.1 - 1e-07 31.3 0.0 0.00083 18.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 CAR30968.1 - 0.046 13.3 0.5 3.2 7.2 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) E1-E2_ATPase PF00122.15 CAR30969.1 - 4.3e-61 205.8 6.5 4.3e-61 205.8 4.5 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CAR30969.1 - 4.5e-33 114.2 0.8 4.5e-33 114.2 0.6 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CAR30969.1 - 5.8e-26 92.2 0.0 1.8e-24 87.3 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CAR30969.1 - 1.2e-18 66.8 0.0 2.4e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CAR30969.1 - 3.3e-14 53.4 0.0 7.4e-14 52.3 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CAR30969.1 - 2.3e-11 42.9 0.0 9.8e-11 40.9 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CAR30969.1 - 0.0035 16.9 0.4 0.015 14.8 0.4 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase FtsJ PF01728.14 CAR30970.1 - 1.6e-63 213.9 0.1 2e-63 213.6 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 CAR30970.1 - 0.056 13.1 0.0 0.091 12.4 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Ribosomal_S10 PF00338.17 CAR30971.1 - 8.8e-29 99.2 0.0 1.3e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e zf-RING_2 PF13639.1 CAR30972.1 - 4.7e-11 42.3 13.0 8.3e-11 41.5 9.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CAR30972.1 - 3.5e-08 33.4 10.0 5.1e-08 32.9 6.5 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CAR30972.1 - 1.3e-05 24.8 7.9 2.2e-05 24.1 5.4 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 CAR30972.1 - 3.9e-05 23.2 13.7 7.9e-05 22.2 9.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAR30972.1 - 0.0048 16.9 13.5 0.0098 15.9 9.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CAR30972.1 - 0.018 14.7 11.5 0.023 14.3 7.3 1.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAR30972.1 - 0.083 12.6 11.1 0.15 11.7 7.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-Nse PF11789.3 CAR30972.1 - 0.088 12.3 8.1 0.18 11.3 5.6 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 CAR30972.1 - 1.1 9.3 12.8 0.74 9.8 6.3 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain zf-P11 PF03854.9 CAR30972.1 - 5 6.6 13.1 10 5.6 7.1 2.2 1 1 1 2 2 2 0 P-11 zinc finger Pkinase PF00069.20 CAR30973.1 - 2.1e-72 243.3 0.2 2.6e-72 243.0 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR30973.1 - 2.2e-45 154.7 0.0 2.9e-45 154.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR30973.1 - 1.4e-08 34.0 0.0 2.8e-08 33.0 0.0 1.5 2 0 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.4 CAR30973.1 - 0.02 14.2 0.5 0.042 13.1 0.1 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kdo PF06293.9 CAR30973.1 - 0.022 13.8 0.0 0.085 11.9 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CAR30973.1 - 0.1 12.3 0.1 0.18 11.5 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family DEAD PF00270.24 CAR30974.1 - 3.3e-29 101.5 0.0 6.5e-29 100.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR30974.1 - 3.1e-14 52.6 0.0 1.7e-13 50.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAR30974.1 - 1.7e-07 31.2 0.0 1.3e-06 28.3 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CAR30974.1 - 1.1e-05 24.4 0.0 1.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SRP72 PF08492.7 CAR30975.1 - 7.3e-09 35.8 8.2 7.3e-09 35.8 5.7 2.4 2 0 0 2 2 2 1 SRP72 RNA-binding domain Apc3 PF12895.2 CAR30975.1 - 5.8e-06 26.3 3.6 0.82 9.8 0.2 3.8 3 1 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 CAR30975.1 - 2.1e-05 24.3 2.6 0.0012 18.7 0.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 CAR30975.1 - 0.0033 17.0 1.3 0.15 11.7 0.2 3.4 3 0 0 3 3 3 1 TPR repeat TPR_14 PF13428.1 CAR30975.1 - 0.0046 17.4 0.0 81 4.2 0.0 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 CAR30975.1 - 0.01 16.1 1.3 13 6.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 CAR30975.1 - 0.016 15.0 4.5 9.1 6.4 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat UPF0113 PF03657.8 CAR30976.1 - 1.1e-11 44.7 0.0 1.4e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) PseudoU_synth_1 PF01416.15 CAR30977.1 - 4.1e-21 75.3 0.0 1.5e-09 38.1 0.0 2.7 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF2344 PF10105.4 CAR30977.1 - 0.026 13.9 0.1 0.15 11.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) DAP3 PF10236.4 CAR30978.1 - 3.7e-80 269.1 2.3 4.2e-80 268.9 0.8 1.6 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 CAR30978.1 - 1.2e-05 25.4 0.0 2.9e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain ArgK PF03308.11 CAR30978.1 - 0.003 16.3 0.4 0.057 12.1 0.0 2.2 2 0 0 2 2 2 1 ArgK protein AAA_22 PF13401.1 CAR30978.1 - 0.0039 17.3 0.0 0.032 14.3 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CAR30978.1 - 0.0062 16.2 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 CAR30978.1 - 0.011 15.3 0.1 0.45 10.1 0.0 2.9 3 0 0 3 3 3 0 NACHT domain DUF258 PF03193.11 CAR30978.1 - 0.028 13.6 0.0 0.072 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 CAR30978.1 - 0.037 13.7 0.0 0.14 11.8 0.0 2.0 1 0 0 1 1 1 0 NTPase ABC_tran PF00005.22 CAR30978.1 - 0.045 14.0 0.0 0.14 12.4 0.0 1.8 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 CAR30978.1 - 0.059 13.2 0.2 0.21 11.4 0.0 2.1 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 CAR30978.1 - 0.067 13.1 0.4 0.61 10.0 0.3 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.1 CAR30978.1 - 0.11 11.9 0.0 0.28 10.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 CAR30978.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain mRNA_cap_enzyme PF01331.14 CAR30979.1 - 2.8e-59 200.0 0.1 5.7e-59 199.0 0.0 1.5 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 CAR30979.1 - 2e-21 76.2 0.5 1.3e-20 73.6 0.3 2.1 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 CAR30979.1 - 8.9e-08 31.7 0.0 6.7e-07 28.8 0.0 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain BAH PF01426.13 CAR30980.1 - 1.1e-16 60.6 0.6 4.8e-16 58.5 0.4 2.2 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H_2 PF13832.1 CAR30980.1 - 1.8e-15 56.8 19.1 2.8e-14 53.0 2.0 4.2 4 0 0 4 4 4 2 PHD-zinc-finger like domain PHD PF00628.24 CAR30980.1 - 2.9e-12 46.0 24.9 8.4e-08 31.7 7.8 6.0 7 0 0 7 7 7 3 PHD-finger zf-HC5HC2H PF13771.1 CAR30980.1 - 6.9e-10 38.9 22.4 5.6e-09 36.0 1.2 4.3 3 0 0 3 3 3 2 PHD-like zinc-binding domain PHD_2 PF13831.1 CAR30980.1 - 2.3e-06 26.8 25.9 4.7e-05 22.6 2.7 5.5 5 0 0 5 5 5 3 PHD-finger C1_1 PF00130.17 CAR30980.1 - 0.0082 15.8 0.8 0.0082 15.8 0.5 6.5 6 1 1 7 7 7 3 Phorbol esters/diacylglycerol binding domain (C1 domain) LRR_9 PF14580.1 CAR30981.1 - 3.4e-12 46.2 0.4 5.7e-12 45.5 0.3 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 CAR30981.1 - 4.2e-08 32.6 13.4 6.7e-05 22.4 1.4 3.3 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAR30981.1 - 0.00043 19.9 10.7 0.025 14.2 3.8 2.8 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 CAR30981.1 - 0.00051 19.6 13.7 1 9.6 0.1 5.1 4 1 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 CAR30981.1 - 0.11 12.7 11.4 13 6.5 0.1 5.2 5 1 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 CAR30981.1 - 0.15 12.2 9.0 17 5.8 0.2 4.7 3 1 0 4 4 4 0 Leucine Rich repeat HK PF02110.10 CAR30982.1 - 1.9e-86 289.2 0.3 3.2e-86 288.5 0.1 1.5 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 CAR30982.1 - 2.4e-59 199.4 0.0 4.1e-59 198.7 0.0 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI UPF0223 PF05256.7 CAR30982.1 - 0.087 12.9 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0223) Phos_pyr_kin PF08543.7 CAR30982.1 - 0.13 11.4 0.6 1.4 8.0 0.4 2.3 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase Ubiq_cyt_C_chap PF03981.7 CAR30983.1 - 3.3e-43 146.9 0.7 5.1e-43 146.3 0.5 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone WAC_Acf1_DNA_bd PF10537.4 CAR30984.1 - 1.7e-36 124.4 1.0 8.2e-36 122.2 0.7 2.3 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 CAR30984.1 - 5.4e-13 48.5 1.5 3.1e-12 46.0 0.3 2.4 2 0 0 2 2 2 1 DDT domain WHIM2 PF15613.1 CAR30984.1 - 4.3e-10 39.1 1.0 1.6e-09 37.3 0.5 2.2 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 2 DUF663 PF04950.7 CAR30985.1 - 3.3e-104 348.0 0.1 3.3e-104 348.0 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 CAR30985.1 - 1.8e-27 94.6 0.0 4.7e-27 93.3 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 CAR30985.1 - 3.3e-07 29.9 0.0 5.7e-06 25.8 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 CAR30985.1 - 1.7e-05 24.9 0.0 4.4e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CAR30985.1 - 4.3e-05 23.4 0.0 0.00013 21.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CAR30985.1 - 5.4e-05 23.2 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 CAR30985.1 - 6.9e-05 23.0 0.0 0.00017 21.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 CAR30985.1 - 8.8e-05 22.1 0.3 0.00023 20.8 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain MobB PF03205.9 CAR30985.1 - 0.00038 20.1 0.2 0.0014 18.3 0.1 2.0 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 CAR30985.1 - 0.0014 19.3 0.0 0.0014 19.3 0.0 3.8 4 0 0 4 4 3 1 AAA domain NACHT PF05729.7 CAR30985.1 - 0.017 14.7 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Miro PF08477.8 CAR30985.1 - 0.027 14.9 0.0 0.12 12.8 0.0 2.2 1 0 0 1 1 1 0 Miro-like protein RNA_helicase PF00910.17 CAR30985.1 - 0.039 14.1 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 CAR30985.1 - 0.039 14.2 0.7 0.27 11.5 0.0 2.7 3 0 0 3 3 3 0 ABC transporter MMR_HSR1 PF01926.18 CAR30985.1 - 0.049 13.5 0.0 0.18 11.7 0.0 2.0 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.9 CAR30985.1 - 0.059 13.0 0.1 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 CAR30985.1 - 0.077 12.4 0.0 0.52 9.8 0.0 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 CAR30985.1 - 0.092 13.0 0.0 0.092 13.0 0.0 3.9 4 0 0 4 4 4 0 AAA domain AAA_11 PF13086.1 CAR30985.1 - 0.22 11.0 0.0 0.22 11.0 0.0 3.0 3 0 0 3 3 2 0 AAA domain Arf PF00025.16 CAR30986.1 - 5.2e-66 221.1 0.0 5.8e-66 221.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 CAR30986.1 - 7.1e-09 34.8 0.9 1.5e-05 23.9 0.0 2.7 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 CAR30986.1 - 2.2e-08 33.5 0.0 2.9e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CAR30986.1 - 6.5e-08 32.1 0.0 8.1e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR30986.1 - 3.4e-07 30.7 0.0 5e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CAR30986.1 - 5.7e-06 26.2 0.0 7.8e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CAR30986.1 - 0.00011 21.7 0.1 0.0017 17.7 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CAR30986.1 - 0.00017 20.8 0.0 0.00019 20.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 CAR30986.1 - 0.066 12.7 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Tegument_dsDNA PF12818.2 CAR30986.1 - 0.1 11.4 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 dsDNA viral tegument protein Cyclin PF08613.6 CAR30987.1 - 9.9e-17 61.7 0.3 2.1e-16 60.6 0.2 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CAR30987.1 - 5.2e-05 22.8 1.1 0.00016 21.2 0.7 1.8 1 1 0 1 1 1 1 Cyclin, N-terminal domain Hormone_3 PF00159.13 CAR30987.1 - 0.046 13.7 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 Pancreatic hormone peptide Ribosomal_L1 PF00687.16 CAR30988.1 - 1.2e-46 158.7 1.9 1.4e-46 158.5 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family FtsJ PF01728.14 CAR30989.1 - 2.5e-55 187.2 0.0 3.4e-55 186.8 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 CAR30989.1 - 2.8e-05 23.8 0.0 0.00012 21.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAR30989.1 - 0.019 14.5 0.0 0.23 11.0 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.2 CAR30989.1 - 0.02 15.4 0.0 0.05 14.1 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Coatomer_WDAD PF04053.9 CAR30990.1 - 3e-156 520.6 0.0 4.1e-156 520.2 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 CAR30990.1 - 1e-47 158.3 9.1 2e-11 43.2 0.1 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 CAR30990.1 - 0.00019 21.1 0.0 4.2 7.1 0.0 4.7 2 1 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 CAR30990.1 - 0.009 14.1 1.0 3.3 5.7 0.0 3.3 3 1 1 4 4 4 2 Nucleoporin Nup120/160 PQQ PF01011.16 CAR30990.1 - 0.024 14.1 2.1 3.2 7.4 0.0 4.4 5 0 0 5 5 5 0 PQQ enzyme repeat Poly_export PF02563.11 CAR30990.1 - 0.033 13.9 0.0 9.2 6.1 0.0 2.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis/export protein TPR_12 PF13424.1 CAR30990.1 - 0.13 12.1 0.9 17 5.4 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 CAR30990.1 - 0.29 11.1 1.2 33 4.7 0.1 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF908 PF06012.7 CAR30991.1 - 0.14 11.3 5.9 0.04 13.2 1.6 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) Striatin PF08232.7 CAR30991.1 - 0.27 11.5 9.5 1.2 9.4 0.1 2.8 3 0 0 3 3 3 0 Striatin family DUF912 PF06024.7 CAR30991.1 - 3.6 7.6 7.6 8.8 6.4 5.3 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Secretin_N_2 PF07655.8 CAR30991.1 - 6.8 7.1 21.0 13 6.2 10.3 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain TRP PF06011.7 CAR30992.1 - 1.4e-147 491.8 36.0 1.9e-147 491.4 24.9 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 CAR30992.1 - 1.4e-41 141.8 1.5 2.4e-41 141.0 1.0 1.4 1 0 0 1 1 1 1 ML-like domain YaeQ PF07152.7 CAR30992.1 - 0.0078 15.5 0.2 0.021 14.1 0.0 1.8 2 0 0 2 2 2 1 YaeQ protein E3_UbLigase_EDD PF11547.3 CAR30992.1 - 0.015 14.7 0.1 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD E1_DerP2_DerF2 PF02221.10 CAR30992.1 - 0.043 14.0 0.2 0.075 13.2 0.1 1.4 1 0 0 1 1 1 0 ML domain Lon_C PF05362.8 CAR30993.1 - 1.5e-42 145.2 0.4 4.1e-42 143.8 0.3 1.8 1 1 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 CAR30993.1 - 6.9e-20 71.5 0.0 2e-19 70.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 CAR30993.1 - 1.8e-09 37.5 0.3 1.8e-09 37.5 0.2 2.1 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain ChlI PF13541.1 CAR30993.1 - 1e-08 34.6 0.5 3.2e-08 33.1 0.3 1.8 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 CAR30993.1 - 2.4e-07 30.5 0.0 1e-06 28.4 0.0 2.1 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CAR30993.1 - 6e-06 27.0 0.2 0.00024 21.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_PrkA PF08298.6 CAR30993.1 - 1.4e-05 24.0 0.1 0.00022 20.0 0.0 2.1 2 0 0 2 2 2 1 PrkA AAA domain AAA_3 PF07726.6 CAR30993.1 - 4.8e-05 22.9 0.0 0.00011 21.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CAR30993.1 - 6.9e-05 22.9 0.0 0.0002 21.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 CAR30993.1 - 0.00025 20.1 0.0 0.00088 18.3 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 CAR30993.1 - 0.00027 20.8 0.0 0.0015 18.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CAR30993.1 - 0.00033 20.7 0.0 0.0079 16.3 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CAR30993.1 - 0.0019 18.1 0.0 0.013 15.3 0.0 2.4 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.1 CAR30993.1 - 0.004 17.4 0.5 0.092 13.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CAR30993.1 - 0.0047 16.6 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 CAR30993.1 - 0.0047 16.1 0.0 0.035 13.2 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 CAR30993.1 - 0.0073 16.0 0.1 0.033 13.8 0.0 2.1 1 1 1 2 2 2 1 NTPase NB-ARC PF00931.17 CAR30993.1 - 0.0077 15.1 0.0 0.018 13.8 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_10 PF12846.2 CAR30993.1 - 0.0098 15.3 0.0 0.076 12.4 0.0 2.2 2 1 0 2 2 2 1 AAA-like domain IstB_IS21 PF01695.12 CAR30993.1 - 0.011 15.1 0.0 0.025 14.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 CAR30993.1 - 0.012 15.6 0.0 0.36 10.8 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_33 PF13671.1 CAR30993.1 - 0.014 15.2 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 CAR30993.1 - 0.017 14.3 0.1 0.16 11.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 CAR30993.1 - 0.017 14.2 0.1 0.063 12.3 0.1 1.9 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 CAR30993.1 - 0.024 14.7 0.0 0.16 12.1 0.0 2.5 2 0 0 2 2 2 0 RNA helicase TIP49 PF06068.8 CAR30993.1 - 0.026 13.2 0.1 0.29 9.7 0.0 2.2 2 0 0 2 2 2 0 TIP49 C-terminus MCM PF00493.18 CAR30993.1 - 0.027 13.2 0.7 0.41 9.3 0.0 2.5 2 0 0 2 2 2 0 MCM2/3/5 family MobB PF03205.9 CAR30993.1 - 0.028 14.1 0.0 0.075 12.7 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B KTI12 PF08433.5 CAR30993.1 - 0.033 13.4 0.0 0.081 12.1 0.0 1.7 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_24 PF13479.1 CAR30993.1 - 0.036 13.6 0.0 0.12 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 CAR30993.1 - 0.038 13.6 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 CAR30993.1 - 0.058 12.9 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain UPF0061 PF02696.9 CAR30994.1 - 3.3e-139 464.3 0.0 4e-139 464.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family GCR1_C PF12550.3 CAR30995.1 - 2.5e-24 84.9 0.2 4.3e-24 84.1 0.1 1.4 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes DUF2457 PF10446.4 CAR30995.1 - 0.098 11.3 12.9 0.21 10.2 9.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Merozoite_SPAM PF07133.6 CAR30995.1 - 0.12 12.3 12.9 0.21 11.4 8.9 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CDC45 PF02724.9 CAR30995.1 - 2.5 6.0 14.0 3.8 5.4 9.7 1.2 1 0 0 1 1 1 0 CDC45-like protein ARID PF01388.16 CAR30997.1 - 2.1e-25 88.3 1.2 5.7e-25 87.0 0.0 2.4 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain JmjC PF02373.17 CAR30997.1 - 5.7e-17 62.0 1.3 1.8e-10 41.0 0.1 3.2 2 0 0 2 2 2 2 JmjC domain, hydroxylase PLU-1 PF08429.6 CAR30997.1 - 6.1e-08 31.9 1.6 2.9e-07 29.6 1.3 2.1 2 0 0 2 2 2 1 PLU-1-like protein PHD PF00628.24 CAR30997.1 - 1e-07 31.4 8.4 1e-07 31.4 5.8 2.0 2 0 0 2 2 2 1 PHD-finger C1_1 PF00130.17 CAR30997.1 - 0.097 12.4 3.2 0.32 10.7 2.2 1.8 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Cation_efflux PF01545.16 CAR30998.1 - 2.8e-39 134.9 7.3 3.9e-39 134.4 5.0 1.1 1 0 0 1 1 1 1 Cation efflux family DUF1149 PF06619.6 CAR30998.1 - 0.056 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1149) Polysacc_synt_4 PF04669.8 CAR30999.1 - 2.7e-22 79.0 0.9 1.6e-20 73.3 0.6 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis Cullin_binding PF03556.10 CAR30999.1 - 0.017 15.2 0.4 0.034 14.2 0.3 1.5 1 0 0 1 1 1 0 Cullin binding DUF2491 PF10679.4 CAR30999.1 - 0.058 12.3 0.4 0.063 12.2 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) MoCF_biosynth PF00994.19 CAR31000.1 - 8e-33 112.8 0.0 1.2e-32 112.3 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain PCI PF01399.22 CAR31000.1 - 0.032 14.5 0.1 0.36 11.1 0.0 2.7 3 1 0 3 3 3 0 PCI domain ABC_tran PF00005.22 CAR31001.1 - 6.6e-48 162.4 0.0 3.9e-25 88.7 0.0 3.6 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CAR31001.1 - 1.6e-13 51.3 18.0 2.5e-08 34.2 0.0 4.8 4 2 0 5 5 4 3 AAA domain SMC_N PF02463.14 CAR31001.1 - 2e-11 43.5 0.0 0.0031 16.7 0.0 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CAR31001.1 - 2.2e-07 30.2 0.2 0.016 14.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Chromo PF00385.19 CAR31001.1 - 5.5e-07 29.1 1.0 1.3e-06 27.9 0.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF258 PF03193.11 CAR31001.1 - 1.4e-06 27.5 0.0 0.0074 15.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 CAR31001.1 - 8.9e-06 25.8 0.0 0.036 14.1 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 CAR31001.1 - 1.1e-05 24.9 1.4 0.64 9.4 0.1 4.0 4 0 0 4 4 4 2 AAA-like domain AAA_17 PF13207.1 CAR31001.1 - 1.2e-05 26.1 0.0 0.43 11.3 0.0 3.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 CAR31001.1 - 1.6e-05 24.8 0.0 0.097 12.6 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 CAR31001.1 - 1.9e-05 25.1 0.0 0.11 12.9 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein DUF87 PF01935.12 CAR31001.1 - 8.5e-05 22.4 1.4 0.09 12.5 0.0 3.7 3 0 0 3 3 3 1 Domain of unknown function DUF87 MobB PF03205.9 CAR31001.1 - 9.7e-05 22.0 0.0 0.15 11.7 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 CAR31001.1 - 0.0002 21.3 0.1 0.35 10.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 CAR31001.1 - 0.00031 20.8 0.1 2 8.5 0.0 3.3 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.7 CAR31001.1 - 0.00031 20.4 0.4 0.44 10.1 0.1 3.0 2 1 0 2 2 2 2 NACHT domain AAA_33 PF13671.1 CAR31001.1 - 0.00035 20.4 0.0 0.41 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 CAR31001.1 - 0.00041 20.7 11.9 0.011 16.1 0.1 3.8 5 0 0 5 5 3 2 AAA domain Dynamin_N PF00350.18 CAR31001.1 - 0.00049 19.9 0.3 0.087 12.6 0.0 3.4 2 1 1 3 3 3 1 Dynamin family SbcCD_C PF13558.1 CAR31001.1 - 0.00065 19.5 0.5 2.4 8.1 0.0 3.8 2 2 1 3 3 3 1 Putative exonuclease SbcCD, C subunit ArgK PF03308.11 CAR31001.1 - 0.00077 18.3 0.1 0.94 8.1 0.0 2.4 2 0 0 2 2 2 2 ArgK protein AAA_18 PF13238.1 CAR31001.1 - 0.0015 18.8 0.4 0.37 11.0 0.0 3.5 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 CAR31001.1 - 0.0016 18.1 0.6 1.5 8.4 0.0 3.0 2 1 0 2 2 2 1 Archaeal ATPase AAA_14 PF13173.1 CAR31001.1 - 0.0017 18.2 0.4 2.4 8.0 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA PF00004.24 CAR31001.1 - 0.0022 18.1 0.1 4.2 7.5 0.0 3.1 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 CAR31001.1 - 0.0099 15.4 0.9 5.9 6.4 0.1 2.9 3 1 0 3 3 2 0 AAA domain DUF815 PF05673.8 CAR31001.1 - 0.017 14.0 0.1 1.9 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 CAR31001.1 - 0.02 13.9 0.1 8.4 5.4 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin AAA_16 PF13191.1 CAR31001.1 - 0.025 14.5 0.5 2.3 8.1 0.0 3.2 3 1 0 3 3 3 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 CAR31001.1 - 0.04 13.3 0.2 3.3 7.1 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family MutS_V PF00488.16 CAR31001.1 - 0.046 13.1 0.1 8.8 5.6 0.0 2.3 2 0 0 2 2 2 0 MutS domain V Thymidylate_kin PF02223.12 CAR31001.1 - 0.054 12.8 0.3 0.64 9.3 0.0 2.6 2 0 0 2 2 2 0 Thymidylate kinase AAA_25 PF13481.1 CAR31001.1 - 0.07 12.5 0.0 8.2 5.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 CAR31001.1 - 0.086 12.5 0.1 16 5.2 0.0 3.0 3 0 0 3 3 3 0 NTPase PduV-EutP PF10662.4 CAR31001.1 - 0.088 12.2 0.2 9.3 5.7 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 CAR31001.1 - 0.093 12.1 0.1 16 4.8 0.0 2.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Glycos_transf_2 PF00535.21 CAR31003.1 - 9.2e-27 93.7 0.0 1.3e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CAR31003.1 - 2.1e-08 34.2 0.0 3.5e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 CAR31003.1 - 0.0037 16.3 0.0 0.005 15.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 CAR31003.1 - 0.018 15.3 0.0 0.033 14.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 mRNA_triPase PF02940.10 CAR31004.1 - 2.9e-55 187.3 0.1 5e-55 186.5 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain HSP20 PF00011.16 CAR31006.1 - 2.6e-18 65.7 2.4 4e-18 65.1 1.7 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family YebF PF13995.1 CAR31006.1 - 0.12 12.4 0.0 19 5.3 0.0 2.3 2 0 0 2 2 2 0 YebF-like protein adh_short_C2 PF13561.1 CAR31007.1 - 1.7e-20 73.8 0.1 1.1e-19 71.1 0.0 2.3 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ketoacyl-synt PF00109.21 CAR31007.1 - 1.9e-19 70.1 0.0 4.1e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 CAR31007.1 - 9.8e-18 64.0 0.0 2.2e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 CAR31007.1 - 7.9e-13 48.3 0.0 2.7e-12 46.5 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 CAR31007.1 - 3.5e-05 23.7 0.0 9.2e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase SNARE PF05739.14 CAR31008.1 - 1.9e-17 62.6 7.8 1.9e-17 62.6 5.4 2.7 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 CAR31008.1 - 1e-08 35.2 1.6 1e-08 35.2 1.1 2.6 2 2 0 2 2 2 1 Syntaxin Synaptobrevin PF00957.16 CAR31008.1 - 0.00019 20.9 2.5 0.00019 20.9 1.7 2.1 2 1 0 2 2 2 1 Synaptobrevin BLOC1_2 PF10046.4 CAR31008.1 - 0.00046 20.2 5.3 0.082 13.0 0.0 2.8 2 1 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.7 CAR31008.1 - 0.00071 19.4 6.4 0.029 14.1 0.1 2.3 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Rifin_STEVOR PF02009.11 CAR31008.1 - 0.0015 18.2 2.7 0.0019 17.8 1.5 1.4 1 1 0 1 1 1 1 Rifin/stevor family T2SF PF00482.18 CAR31008.1 - 0.0033 17.3 0.8 0.0074 16.1 0.1 1.9 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein F AATase PF07247.7 CAR31008.1 - 0.0098 14.4 1.6 0.064 11.7 0.0 2.0 2 0 0 2 2 2 1 Alcohol acetyltransferase UPF0184 PF03670.8 CAR31008.1 - 0.059 13.5 0.2 0.059 13.5 0.1 3.4 2 2 3 5 5 5 0 Uncharacterised protein family (UPF0184) Fib_alpha PF08702.5 CAR31008.1 - 0.27 11.3 13.5 1.5 8.9 0.6 2.9 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family PBP1_TM PF14812.1 CAR31008.1 - 0.29 11.4 0.1 0.29 11.4 0.1 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF848 PF05852.6 CAR31008.1 - 0.42 10.4 10.3 0.5 10.2 1.9 2.4 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF4094 PF13334.1 CAR31008.1 - 0.45 10.9 3.3 0.52 10.7 0.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) DUF2077 PF09850.4 CAR31008.1 - 0.46 9.8 3.9 2 7.7 0.0 2.8 2 2 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2077) DUF3708 PF12501.3 CAR31008.1 - 0.92 9.3 6.3 1.5 8.6 0.7 2.7 1 1 2 3 3 3 0 Phosphate ATP-binding cassette transporter DUF2562 PF10814.3 CAR31008.1 - 1.2 9.1 4.5 1.6 8.6 1.8 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2562) SlyX PF04102.7 CAR31008.1 - 3.4 8.1 10.5 0.17 12.2 2.6 2.3 2 1 0 2 2 2 0 SlyX DUF3810 PF12725.2 CAR31008.1 - 3.4 6.4 6.0 11 4.7 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3810) DUF2203 PF09969.4 CAR31008.1 - 3.5 7.8 9.7 0.82 9.8 1.3 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) FliT PF05400.8 CAR31008.1 - 3.7 8.0 17.4 0.92 9.9 1.9 3.0 2 2 1 3 3 3 0 Flagellar protein FliT DUF755 PF05501.6 CAR31008.1 - 3.7 7.6 9.9 8.1 6.5 1.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF755) DUF1542 PF07564.6 CAR31008.1 - 5.9 6.9 10.3 11 6.1 1.9 3.4 3 1 0 3 3 3 0 Domain of Unknown Function (DUF1542) DUF1664 PF07889.7 CAR31008.1 - 6.3 6.6 9.8 2 8.2 2.7 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) Mis14 PF08641.7 CAR31009.1 - 1.3e-15 57.6 1.2 2.1e-15 57.0 0.9 1.3 1 0 0 1 1 1 1 Kinetochore protein Mis14 like Talin_middle PF09141.5 CAR31009.1 - 0.12 11.9 0.4 0.18 11.4 0.3 1.2 1 0 0 1 1 1 0 Talin, middle domain Med30 PF11315.3 CAR31009.1 - 1.9 8.6 5.1 2 8.5 0.3 2.4 3 0 0 3 3 3 0 Mediator complex subunit 30 ATP-synt_C PF00137.16 CAR31010.1 - 1.9e-28 98.1 27.1 9.6e-16 57.4 3.0 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Polysacc_synt_3 PF13440.1 CAR31010.1 - 0.003 17.0 0.9 0.003 17.0 0.6 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein TIP49 PF06068.8 CAR31011.1 - 1e-177 590.8 5.8 1.2e-177 590.6 4.1 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 CAR31011.1 - 8.7e-08 32.4 0.7 0.00014 22.0 0.1 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CAR31011.1 - 6.8e-07 28.5 2.6 0.00065 18.8 0.0 2.7 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 CAR31011.1 - 6.5e-06 25.2 0.1 1.3e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.1 CAR31011.1 - 0.00014 21.9 0.1 0.065 13.3 0.0 2.7 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 CAR31011.1 - 0.00072 19.5 0.0 0.0075 16.2 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 CAR31011.1 - 0.0031 17.3 0.1 1.7 8.5 0.0 2.8 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.16 CAR31011.1 - 0.0087 15.2 0.6 0.19 10.8 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CAR31011.1 - 0.019 14.6 0.4 4.3 7.0 0.0 3.1 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CAR31011.1 - 0.024 14.0 0.2 0.045 13.1 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 CAR31011.1 - 0.12 12.2 0.1 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.20 CAR31012.1 - 4.1e-37 127.7 0.0 4.1e-26 91.6 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAR31012.1 - 1.5e-16 60.2 0.0 1.1e-15 57.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR31012.1 - 0.028 13.3 0.0 0.059 12.3 0.0 1.6 1 0 0 1 1 1 0 Kinase-like eIF-5_eIF-2B PF01873.12 CAR31014.1 - 1e-45 154.3 0.1 1.5e-45 153.8 0.1 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 IF2_N PF04760.10 CAR31014.1 - 0.018 14.6 0.1 0.11 12.1 0.0 2.3 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region TF_Zn_Ribbon PF08271.7 CAR31014.1 - 0.11 11.8 0.1 0.24 10.7 0.1 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding Ank_4 PF13637.1 CAR31015.1 - 4.8e-18 65.1 0.0 1.2e-12 47.9 0.0 2.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CAR31015.1 - 3.5e-16 59.2 0.1 7.3e-16 58.2 0.1 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CAR31015.1 - 1.1e-15 56.5 0.1 4.6e-07 29.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 CAR31015.1 - 1.9e-15 56.5 0.1 4.7e-08 33.0 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CAR31015.1 - 1.6e-13 49.4 0.1 2.6e-05 24.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat DUF2435 PF10363.4 CAR31016.1 - 8.3e-25 86.5 0.6 8.3e-25 86.5 0.4 3.8 4 0 0 4 4 4 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 CAR31016.1 - 9.5e-05 21.8 0.9 0.00051 19.5 0.6 2.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) MCM_N PF14551.1 CAR31016.1 - 0.12 12.9 5.4 0.18 12.3 0.5 3.1 2 1 0 2 2 2 0 MCM N-terminal domain HSP90 PF00183.13 CAR31017.1 - 3.9e-251 834.0 39.6 4.7e-251 833.8 27.5 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 CAR31017.1 - 2.5e-11 43.3 0.0 2.5e-11 43.3 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CAR31017.1 - 1.3e-10 40.9 0.0 2.3e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2722 PF10846.3 CAR31017.1 - 0.65 8.9 9.8 6.7 5.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) TBCC PF07986.7 CAR31018.1 - 1.7e-09 37.0 4.1 8.9e-09 34.7 2.8 1.9 1 1 0 1 1 1 1 Tubulin binding cofactor C Carbpep_Y_N PF05388.6 CAR31018.1 - 0.0053 16.9 0.3 0.0088 16.1 0.2 1.4 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide DUF2321 PF10083.4 CAR31018.1 - 0.62 9.5 3.2 4.5 6.7 0.1 2.3 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Rpr2 PF04032.11 CAR31018.1 - 1.5 8.7 4.6 6.4 6.7 0.7 2.4 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain RasGAP_C PF03836.10 CAR31019.1 - 4.6e-26 91.2 7.6 1.4e-25 89.6 5.2 1.9 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 CAR31019.1 - 2.9e-17 63.0 2.2 2.9e-17 63.0 1.5 2.8 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CH PF00307.26 CAR31019.1 - 7.4e-08 32.3 0.0 4e-07 30.0 0.0 2.4 1 0 0 1 1 1 1 Calponin homology (CH) domain IQ PF00612.22 CAR31019.1 - 3.7e-05 22.9 24.8 0.48 10.1 0.1 8.4 9 0 0 9 9 9 3 IQ calmodulin-binding motif Herpes_HEPA PF03324.9 CAR31019.1 - 0.021 14.8 0.0 4.5 7.3 0.0 2.7 2 0 0 2 2 2 0 Herpesvirus DNA helicase/primase complex associated protein Rho_Binding PF08912.6 CAR31019.1 - 0.16 12.2 5.1 0.41 10.9 0.1 3.3 2 0 0 2 2 2 0 Rho Binding DUF745 PF05335.8 CAR31019.1 - 0.34 10.4 0.0 0.72 9.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF745) NPV_P10 PF05531.7 CAR31019.1 - 0.75 10.0 7.2 0.65 10.2 0.1 3.7 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein RINGv PF12906.2 CAR31020.1 - 0.003 17.5 8.4 0.0037 17.2 4.1 2.3 2 0 0 2 2 2 1 RING-variant domain DUF3797 PF12677.2 CAR31020.1 - 0.48 10.0 0.0 0.48 10.0 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3797) FANCL_C PF11793.3 CAR31020.1 - 2.3 8.2 13.3 9.8 6.2 4.3 3.3 3 0 0 3 3 3 0 FANCL C-terminal domain DUF1104 PF06518.6 CAR31021.1 - 0.54 10.4 14.2 8.3 6.6 1.0 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1104) UAA PF08449.6 CAR31022.1 - 1.3e-73 247.5 11.9 1.5e-73 247.4 8.2 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 CAR31022.1 - 1.3e-07 31.7 19.3 6.4e-07 29.4 3.8 3.2 2 1 0 3 3 3 2 EamA-like transporter family TPT PF03151.11 CAR31022.1 - 5.4e-06 26.1 6.7 5.4e-06 26.1 4.6 2.8 2 1 0 2 2 2 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 CAR31022.1 - 0.00072 18.7 6.9 0.11 11.5 4.0 2.2 1 1 1 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 CAR31022.1 - 0.0027 17.8 7.1 0.0027 17.8 4.9 3.2 2 1 1 3 3 3 2 Multidrug resistance efflux transporter DUF1664 PF07889.7 CAR31022.1 - 0.33 10.7 1.8 0.52 10.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) UPF0546 PF10639.4 CAR31022.1 - 4.4 7.1 7.5 7.2 6.4 1.1 2.7 2 1 1 3 3 3 0 Uncharacterised protein family UPF0546 DUF2075 PF09848.4 CAR31023.1 - 1.7e-103 346.3 0.0 2e-103 346.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 CAR31023.1 - 8e-08 32.4 0.1 3.4e-07 30.4 0.1 1.9 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 CAR31023.1 - 9.3e-05 22.4 0.0 0.0002 21.4 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 CAR31023.1 - 0.00045 20.4 0.0 0.00089 19.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 CAR31023.1 - 0.00045 20.0 0.4 0.53 10.0 0.1 2.3 1 1 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_30 PF13604.1 CAR31023.1 - 0.0016 18.0 0.1 0.052 13.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 CAR31023.1 - 0.0089 15.7 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DAP3 PF10236.4 CAR31023.1 - 0.015 14.2 0.0 0.032 13.1 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 PIF1 PF05970.9 CAR31023.1 - 0.021 13.7 0.1 0.04 12.8 0.0 1.6 1 1 0 1 1 1 0 PIF1-like helicase T2SE PF00437.15 CAR31023.1 - 0.024 13.5 0.1 0.041 12.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF258 PF03193.11 CAR31023.1 - 0.041 13.0 0.5 0.071 12.2 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 CAR31023.1 - 0.045 13.9 0.0 0.22 11.7 0.0 2.3 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 CAR31023.1 - 0.069 13.0 0.1 0.19 11.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 CAR31023.1 - 0.069 13.6 0.7 1 9.8 0.2 2.6 2 1 0 2 2 1 0 Miro-like protein MMR_HSR1 PF01926.18 CAR31023.1 - 0.079 12.9 0.2 0.24 11.3 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase Bac_DnaA PF00308.13 CAR31023.1 - 0.081 12.5 0.7 1.2 8.6 0.3 2.4 1 1 0 2 2 2 0 Bacterial dnaA protein AAA_19 PF13245.1 CAR31023.1 - 0.11 12.3 0.0 0.3 10.8 0.0 1.7 2 0 0 2 2 1 0 Part of AAA domain Rhomboid PF01694.17 CAR31024.1 - 2e-19 70.0 10.2 3.5e-19 69.2 7.1 1.3 1 0 0 1 1 1 1 Rhomboid family DUF1129 PF06570.6 CAR31024.1 - 0.0051 16.1 0.6 0.0084 15.4 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1129) Ribosomal_S17 PF00366.15 CAR31025.1 - 1.5e-15 56.9 0.3 2.8e-15 56.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 Spectrin PF00435.16 CAR31025.1 - 0.3 11.3 5.1 0.14 12.4 1.1 2.1 1 1 1 2 2 2 0 Spectrin repeat WD40 PF00400.27 CAR31026.1 - 5.9e-23 79.8 8.0 6.3e-08 32.2 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat GDC-P PF02347.11 CAR31027.1 - 2.8e-195 649.0 0.0 7e-182 604.8 0.0 3.2 2 1 0 2 2 2 2 Glycine cleavage system P-protein Aminotran_5 PF00266.14 CAR31027.1 - 1.4e-05 23.9 0.1 5.8e-05 21.9 0.0 1.9 2 1 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CAR31027.1 - 1.8e-05 24.0 0.0 6.1e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 CAR31027.1 - 0.00058 18.9 0.0 0.028 13.3 0.0 2.6 3 0 0 3 3 3 1 Aminotransferase class I and II MFS_1 PF07690.11 CAR31028.1 - 1.7e-23 82.9 13.8 1.8e-22 79.5 9.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily RQC PF09382.5 CAR31029.1 - 6.7e-29 99.7 0.0 1.6e-28 98.5 0.0 1.7 1 0 0 1 1 1 1 RQC domain Helicase_Sgs1 PF11408.3 CAR31029.1 - 8.3e-24 83.2 0.1 2.8e-23 81.5 0.1 2.0 1 0 0 1 1 1 1 Sgs1 RecQ helicase DEAD PF00270.24 CAR31029.1 - 3.4e-21 75.4 0.1 3.2e-20 72.3 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR31029.1 - 2.3e-18 65.7 2.3 7.2e-17 61.0 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HRDC PF00570.18 CAR31029.1 - 8.2e-05 22.2 0.0 0.00021 20.9 0.0 1.6 1 0 0 1 1 1 1 HRDC domain GlutR_dimer PF00745.15 CAR31029.1 - 0.015 15.1 0.4 0.082 12.8 0.2 2.4 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF3907 PF13047.1 CAR31029.1 - 0.031 13.8 1.1 0.12 12.0 0.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3907) Fungal_trans PF04082.13 CAR31030.1 - 6.7e-30 103.8 1.1 1.2e-29 102.9 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gal4_dimer PF03902.8 CAR31030.1 - 6.8e-16 57.9 1.4 1.6e-15 56.7 1.0 1.6 1 0 0 1 1 1 1 Gal4-like dimerisation domain Zn_clus PF00172.13 CAR31030.1 - 1.5e-08 34.3 17.0 3.1e-08 33.4 11.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RabGAP-TBC PF00566.13 CAR31032.1 - 8.1e-49 165.9 0.8 8.1e-49 165.9 0.6 2.7 3 0 0 3 3 3 2 Rab-GTPase-TBC domain ACOX PF01756.14 CAR31033.1 - 1.1e-44 152.0 0.1 2.1e-44 151.1 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 CAR31033.1 - 2.4e-12 46.1 0.1 4.2e-12 45.3 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 CAR31033.1 - 4.7e-11 43.0 0.1 1.4e-10 41.5 0.1 1.8 1 1 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.19 CAR31033.1 - 0.021 14.9 0.0 0.053 13.6 0.0 1.6 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Clathrin PF00637.15 CAR31034.1 - 2.1e-189 620.6 56.6 1.4e-31 109.0 0.0 8.8 10 0 0 10 10 10 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 CAR31034.1 - 3.7e-25 87.5 0.2 1.4e-24 85.7 0.1 2.1 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.15 CAR31034.1 - 3.6e-20 70.8 6.9 1.9e-06 27.7 0.1 6.0 5 0 0 5 5 5 5 Clathrin propeller repeat Clathrin-link PF09268.5 CAR31034.1 - 1.3e-08 33.6 0.3 1.3e-08 33.6 0.2 3.0 3 0 0 3 3 3 1 Clathrin, heavy-chain linker TPR_19 PF14559.1 CAR31034.1 - 0.014 15.6 4.7 12 6.3 0.1 4.5 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.15 CAR31034.1 - 0.091 12.7 2.5 96 3.2 0.0 5.5 5 1 1 6 6 6 0 PPR repeat SPT16 PF08644.6 CAR31035.1 - 3.2e-50 169.9 0.1 3.2e-50 169.9 0.1 2.1 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 CAR31035.1 - 5.1e-47 159.4 4.8 1.1e-46 158.3 0.2 3.2 3 0 0 3 3 3 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 CAR31035.1 - 3.4e-24 85.5 0.0 5.7e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 CAR31035.1 - 3.3e-19 68.6 2.2 1.5e-18 66.5 0.1 2.9 3 0 0 3 3 3 1 Histone chaperone Rttp106-like AMPKBI PF04739.10 CAR31036.1 - 7.9e-32 109.1 2.3 1.6e-31 108.1 1.6 1.5 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interation domain zf-H2C2_2 PF13465.1 CAR31037.1 - 2.1e-11 43.4 17.9 3.5e-07 30.1 4.4 3.3 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 CAR31037.1 - 3.3e-10 39.7 15.6 1.6e-06 28.1 1.9 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CAR31037.1 - 7.7e-09 35.2 12.2 1.2e-05 25.3 0.7 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CAR31037.1 - 0.00011 22.2 7.2 0.0084 16.2 1.2 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CAR31037.1 - 0.0065 16.6 3.3 0.32 11.2 0.4 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 CAR31037.1 - 0.42 10.3 9.7 1.5 8.5 0.4 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF629 PF04780.7 CAR31037.1 - 1.6 7.1 3.8 1.5 7.2 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.2 CAR31037.1 - 4.8 7.3 6.0 24 5.1 0.2 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 CAR31037.1 - 5.8 6.7 7.8 1.7 8.4 0.2 2.4 1 1 1 2 2 2 0 BED zinc finger LSM PF01423.17 CAR31038.1 - 8e-17 60.5 0.2 1.5e-16 59.6 0.1 1.5 1 0 0 1 1 1 1 LSM domain HTH_Tnp_Tc3_2 PF01498.13 CAR31038.1 - 0.0023 17.9 0.1 0.0047 16.9 0.1 1.5 1 0 0 1 1 1 1 Transposase SM-ATX PF14438.1 CAR31038.1 - 0.14 12.1 0.2 0.39 10.6 0.0 1.8 2 0 0 2 2 2 0 Ataxin 2 SM domain RNase_H2-Ydr279 PF09468.5 CAR31038.1 - 0.17 11.0 6.5 0.22 10.7 4.5 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) CHZ PF09649.5 CAR31039.1 - 3.2e-20 71.0 0.9 3.2e-20 71.0 0.6 2.4 2 0 0 2 2 2 1 Histone chaperone domain CHZ ORC6 PF05460.8 CAR31039.1 - 3.3 6.7 17.6 4.3 6.3 12.2 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Ras PF00071.17 CAR31040.1 - 8.7e-61 204.0 0.1 1e-60 203.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR31040.1 - 9.2e-20 71.3 0.0 1.5e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAR31040.1 - 5.5e-13 48.5 0.0 7.1e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CAR31040.1 - 3.2e-07 30.2 0.0 4.5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.1 CAR31040.1 - 2.8e-05 23.3 0.1 3.4e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.22 CAR31040.1 - 5.4e-05 22.6 0.1 0.00015 21.2 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CAR31040.1 - 0.00087 18.4 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 CAR31040.1 - 0.0024 17.0 0.2 0.0049 16.0 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 CAR31040.1 - 0.0098 15.3 0.0 0.019 14.4 0.0 1.5 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 CAR31040.1 - 0.011 15.8 0.1 0.025 14.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.5 CAR31040.1 - 0.013 14.6 0.0 0.02 14.1 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.13 CAR31040.1 - 0.016 14.2 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_16 PF13191.1 CAR31040.1 - 0.019 14.9 0.2 0.068 13.1 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain KAP_NTPase PF07693.9 CAR31040.1 - 0.049 12.6 0.0 0.067 12.1 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain ABC_tran PF00005.22 CAR31040.1 - 0.054 13.7 0.4 0.085 13.1 0.3 1.5 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.13 CAR31040.1 - 0.093 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B DUF1128 PF06569.6 CAR31040.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) TraG_N PF07916.6 CAR31040.1 - 0.15 10.4 0.0 0.18 10.2 0.0 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region ATP_bind_3 PF01171.15 CAR31043.1 - 6.4e-17 61.6 0.0 1.6e-16 60.3 0.0 1.7 1 1 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 CAR31043.1 - 0.00066 19.9 0.0 0.0015 18.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) PX PF00787.19 CAR31044.1 - 7.9e-14 51.4 1.8 9.3e-14 51.1 0.2 1.9 2 0 0 2 2 2 1 PX domain SNARE PF05739.14 CAR31044.1 - 5.4e-09 35.6 6.8 1.3e-08 34.4 4.7 1.7 1 0 0 1 1 1 1 SNARE domain FAM219A PF15260.1 CAR31044.1 - 0.46 10.8 4.0 0.55 10.5 1.9 1.8 1 1 0 1 1 1 0 Protein family FAM219A WD40 PF00400.27 CAR31045.1 - 8.8e-17 60.2 15.0 1.2e-08 34.5 0.1 6.0 6 1 0 6 6 6 3 WD domain, G-beta repeat Nbas_N PF15492.1 CAR31045.1 - 0.046 12.8 0.0 3.8 6.5 0.0 2.3 1 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Amidase PF01425.16 CAR31046.1 - 2.5e-32 112.3 0.1 4.2e-32 111.5 0.1 1.3 1 0 0 1 1 1 1 Amidase Cyclin PF08613.6 CAR31047.1 - 0.001 19.4 7.1 0.0054 17.1 4.9 2.3 1 1 0 1 1 1 1 Cyclin Hom_end_hint PF05203.11 CAR31047.1 - 0.027 14.1 0.1 0.028 14.1 0.1 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint Cyclin_N PF00134.18 CAR31047.1 - 0.061 12.8 0.1 0.061 12.8 0.1 2.5 3 1 0 3 3 3 0 Cyclin, N-terminal domain TFIIA PF03153.8 CAR31047.1 - 0.26 11.1 20.7 0.4 10.5 14.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 CAR31047.1 - 2 6.5 37.0 3 5.9 25.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Kinesin PF00225.18 CAR31048.1 - 3.4e-113 377.7 0.4 5.1e-113 377.1 0.3 1.2 1 0 0 1 1 1 1 Kinesin motor domain BolA PF01722.13 CAR31050.1 - 4.7e-18 64.9 0.0 7.6e-18 64.2 0.0 1.4 1 1 0 1 1 1 1 BolA-like protein FANCI_HD1 PF14679.1 CAR31050.1 - 0.1 12.3 0.2 0.2 11.4 0.0 1.6 2 0 0 2 2 2 0 FANCI helical domain 1 NIF3 PF01784.13 CAR31051.1 - 2.1e-62 210.8 0.0 2.5e-62 210.5 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) DUF3987 PF13148.1 CAR31052.1 - 7 5.1 8.8 9.6 4.6 4.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3987) PAT1 PF09770.4 CAR31053.1 - 4.8 5.3 27.6 7.2 4.7 19.2 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ABC_tran PF00005.22 CAR31054.1 - 7.9e-50 168.7 0.1 3.2e-25 88.9 0.0 3.0 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 CAR31054.1 - 6.2e-22 78.9 2.7 4.5e-06 26.8 0.0 4.4 2 2 2 4 4 4 4 AAA domain ABC_tran_2 PF12848.2 CAR31054.1 - 1.2e-20 73.0 0.7 1.2e-20 73.0 0.5 3.0 3 0 0 3 3 2 1 ABC transporter SMC_N PF02463.14 CAR31054.1 - 1.9e-09 37.0 1.2 0.73 9.0 0.0 4.8 3 1 1 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CAR31054.1 - 2.5e-08 33.3 0.0 0.0016 17.9 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CAR31054.1 - 4.5e-08 33.9 0.6 0.002 18.9 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CAR31054.1 - 1.2e-07 31.8 0.0 0.029 14.5 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 CAR31054.1 - 1.6e-07 31.6 0.4 0.019 15.2 0.0 3.3 4 0 0 4 4 2 2 AAA domain DUF258 PF03193.11 CAR31054.1 - 3e-07 29.7 0.0 0.00028 20.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 CAR31054.1 - 3.3e-07 30.8 0.0 0.0073 16.8 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 CAR31054.1 - 1e-05 25.4 0.1 0.048 13.6 0.1 3.2 3 1 0 3 3 2 2 50S ribosome-binding GTPase AAA_14 PF13173.1 CAR31054.1 - 1.3e-05 25.1 0.0 0.071 13.0 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA PF00004.24 CAR31054.1 - 1.4e-05 25.3 0.4 0.23 11.6 0.0 3.8 3 2 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 CAR31054.1 - 2.5e-05 24.2 0.0 0.1 12.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 CAR31054.1 - 2.6e-05 23.9 0.2 0.26 10.9 0.0 2.7 2 0 0 2 2 2 2 NACHT domain RNA_helicase PF00910.17 CAR31054.1 - 2.7e-05 24.3 0.1 0.32 11.2 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_15 PF13175.1 CAR31054.1 - 3.3e-05 23.1 0.0 0.44 9.5 0.0 3.7 4 1 0 4 4 3 2 AAA ATPase domain AAA_28 PF13521.1 CAR31054.1 - 3.9e-05 23.6 0.0 0.31 10.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 CAR31054.1 - 4.4e-05 23.8 0.1 0.0031 17.8 0.0 4.1 4 1 0 5 5 3 2 AAA domain Arch_ATPase PF01637.13 CAR31054.1 - 9.2e-05 22.2 0.2 0.4 10.3 0.0 3.4 3 0 0 3 3 3 1 Archaeal ATPase AAA_16 PF13191.1 CAR31054.1 - 0.00011 22.2 0.8 0.39 10.6 0.1 3.1 3 2 0 3 3 2 2 AAA ATPase domain VirE PF05272.6 CAR31054.1 - 0.00027 20.4 0.1 0.44 9.9 0.0 3.0 3 0 0 3 3 3 1 Virulence-associated protein E AAA_25 PF13481.1 CAR31054.1 - 0.00047 19.6 0.1 1.9 7.8 0.0 3.1 3 1 0 3 3 3 2 AAA domain AAA_10 PF12846.2 CAR31054.1 - 0.00051 19.5 0.4 0.82 9.0 0.0 3.4 3 1 0 3 3 3 1 AAA-like domain Dynamin_N PF00350.18 CAR31054.1 - 0.00099 18.9 0.2 0.75 9.5 0.0 3.5 2 1 1 3 3 3 1 Dynamin family MobB PF03205.9 CAR31054.1 - 0.0012 18.6 0.2 0.035 13.7 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MCM PF00493.18 CAR31054.1 - 0.0019 17.0 0.9 2.1 7.0 0.0 3.0 3 0 0 3 3 3 1 MCM2/3/5 family SbcCD_C PF13558.1 CAR31054.1 - 0.0025 17.6 0.3 0.58 10.1 0.0 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 CAR31054.1 - 0.0057 16.3 0.2 3.4 7.4 0.1 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) T2SE PF00437.15 CAR31054.1 - 0.011 14.6 0.0 0.15 10.9 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein G-alpha PF00503.15 CAR31054.1 - 0.012 14.2 0.0 4 6.0 0.0 3.0 3 0 0 3 3 3 0 G-protein alpha subunit ArgK PF03308.11 CAR31054.1 - 0.013 14.2 0.0 3.6 6.2 0.0 2.6 3 0 0 3 3 2 0 ArgK protein NB-ARC PF00931.17 CAR31054.1 - 0.014 14.3 0.0 3.3 6.5 0.0 2.9 2 1 0 2 2 2 0 NB-ARC domain Rad17 PF03215.10 CAR31054.1 - 0.016 13.9 0.1 2.6 6.6 0.0 2.4 3 0 0 3 3 3 0 Rad17 cell cycle checkpoint protein PduV-EutP PF10662.4 CAR31054.1 - 0.017 14.6 0.1 12 5.3 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DAP3 PF10236.4 CAR31054.1 - 0.03 13.2 1.1 5.6 5.8 0.0 2.8 3 0 0 3 3 2 0 Mitochondrial ribosomal death-associated protein 3 DUF815 PF05673.8 CAR31054.1 - 0.03 13.2 0.0 7.7 5.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Ras PF00071.17 CAR31054.1 - 0.046 13.0 0.0 9 5.6 0.0 2.5 2 0 0 2 2 2 0 Ras family FtsK_SpoIIIE PF01580.13 CAR31054.1 - 0.048 13.1 0.0 1.2 8.5 0.0 2.6 2 1 1 3 3 3 0 FtsK/SpoIIIE family NTPase_1 PF03266.10 CAR31054.1 - 0.068 12.8 0.1 2.9 7.5 0.0 2.6 2 0 0 2 2 2 0 NTPase FeoB_N PF02421.13 CAR31054.1 - 0.073 12.3 0.1 3 7.0 0.0 2.7 3 0 0 3 3 2 0 Ferrous iron transport protein B DUF87 PF01935.12 CAR31054.1 - 0.24 11.1 4.1 24 4.6 0.0 3.9 3 1 1 4 4 4 0 Domain of unknown function DUF87 SH3_7 PF12914.2 CAR31055.1 - 0.096 12.4 0.0 0.31 10.8 0.0 1.9 2 0 0 2 2 2 0 SH3 domain of SH3b2 type HAD_2 PF13419.1 CAR31056.1 - 1.8e-21 77.1 0.0 2.2e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CAR31056.1 - 5.9e-05 23.5 0.0 0.0011 19.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Nse5 PF08691.5 CAR31057.1 - 9.6e-22 77.1 13.5 2.1e-21 76.0 9.3 1.5 1 1 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 UAA PF08449.6 CAR31058.1 - 4.2e-15 55.4 18.1 1.3e-14 53.7 12.6 1.8 1 1 1 2 2 2 1 UAA transporter family TPT PF03151.11 CAR31058.1 - 4.4e-09 36.1 8.7 4.4e-09 36.1 6.0 2.7 2 1 0 2 2 2 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 CAR31058.1 - 0.00021 20.4 1.6 0.00021 20.4 1.1 1.9 3 0 0 3 3 3 1 Nucleotide-sugar transporter EamA PF00892.15 CAR31058.1 - 0.00064 19.7 26.1 0.042 13.9 4.8 2.4 2 1 0 2 2 2 2 EamA-like transporter family Helicase_C_4 PF13871.1 CAR31058.1 - 0.085 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Helicase_C-like GATA PF00320.22 CAR31059.1 - 5e-14 51.3 5.6 1.3e-13 50.0 3.9 1.8 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 CAR31059.1 - 0.029 13.7 0.4 0.063 12.6 0.3 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding XPG_I PF00867.13 CAR31060.1 - 9.9e-23 80.0 0.0 2.2e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CAR31060.1 - 3e-05 24.1 0.0 6.7e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 CAR31060.1 - 0.0063 16.0 0.0 0.062 12.7 0.0 2.1 2 0 0 2 2 2 1 XPG domain containing PMSR PF01625.16 CAR31061.1 - 1.5e-48 164.6 0.1 1.9e-48 164.2 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Ist1 PF03398.9 CAR31061.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway COX4 PF02936.9 CAR31062.1 - 1.3e-14 54.1 0.1 1.5e-14 53.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV UPF0197 PF05251.7 CAR31063.1 - 0.012 15.8 5.0 0.016 15.4 3.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0197) PTPS_related PF10131.4 CAR31063.1 - 0.018 13.2 0.8 0.02 13.0 0.5 1.0 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein YjgP_YjgQ PF03739.9 CAR31063.1 - 0.065 11.9 2.9 0.068 11.8 2.0 1.0 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family OppC_N PF12911.2 CAR31063.1 - 6 6.3 6.2 0.7 9.3 0.2 2.2 2 1 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C SPRY PF00622.23 CAR31064.1 - 3.6e-21 75.5 0.3 8.1e-21 74.3 0.2 1.6 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.4 CAR31064.1 - 4.9e-14 52.2 6.2 3.4e-13 49.5 3.1 2.3 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain Ubiq_cyt_C_chap PF03981.7 CAR31064.1 - 0.072 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone Daxx PF03344.10 CAR31064.1 - 5.5 5.3 20.3 0.032 12.7 7.5 1.7 2 0 0 2 2 2 0 Daxx Family AdoHcyase PF05221.12 CAR31065.1 - 3.2e-140 465.6 0.1 3.6e-140 465.4 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 CAR31065.1 - 1.9e-85 284.7 2.2 2.9e-85 284.0 1.5 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 CAR31065.1 - 5.4e-07 28.9 0.1 1e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 CAR31065.1 - 6.7e-05 22.3 0.3 0.00013 21.4 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 CAR31065.1 - 0.004 17.1 0.1 0.0084 16.1 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain RPM2 PF08579.6 CAR31065.1 - 0.049 13.7 0.0 0.16 12.0 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial ribonuclease P subunit (RPM2) Apolipoprotein PF01442.13 CAR31066.1 - 1.5e-05 24.6 10.1 0.07 12.6 2.3 4.7 3 2 1 4 4 4 2 Apolipoprotein A1/A4/E domain DUF2937 PF11157.3 CAR31066.1 - 0.033 13.5 0.3 0.52 9.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) ATP-synt_E_2 PF08112.6 CAR31066.1 - 0.034 14.2 0.6 0.22 11.6 0.0 2.7 3 0 0 3 3 3 0 ATP synthase epsilon subunit FlaC_arch PF05377.6 CAR31066.1 - 0.077 12.8 3.2 3.9 7.4 0.0 3.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Sec8_exocyst PF04048.9 CAR31066.1 - 0.079 12.6 5.3 3.4 7.2 0.2 3.5 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain PRANC PF09372.5 CAR31066.1 - 0.35 10.8 3.5 0.39 10.6 0.2 2.8 2 0 0 2 2 2 0 PRANC domain SAPS PF04499.10 CAR31067.1 - 9.7e-160 532.2 49.6 1.6e-101 340.3 8.8 3.0 2 1 1 3 3 3 2 SIT4 phosphatase-associated protein DnaJ PF00226.26 CAR31068.1 - 3.1e-15 55.6 1.1 7.2e-15 54.4 0.7 1.7 1 0 0 1 1 1 1 DnaJ domain Elongin_A PF06881.6 CAR31068.1 - 3.5 8.0 7.8 0.14 12.5 0.5 2.1 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Adaptin_binding PF10199.4 CAR31070.1 - 0.0012 19.1 5.4 0.043 14.1 0.0 2.7 2 1 1 3 3 3 2 Alpha and gamma adaptin binding protein p34 MgtE_N PF03448.12 CAR31070.1 - 0.014 15.7 0.3 0.035 14.4 0.1 1.7 2 0 0 2 2 2 0 MgtE intracellular N domain Chordopox_A30L PF06015.7 CAR31071.1 - 0.035 13.7 0.3 0.38 10.3 0.0 2.1 1 1 1 2 2 2 0 Chordopoxvirus A30L protein zf-DHHC PF01529.15 CAR31071.1 - 0.089 12.1 0.2 0.12 11.7 0.2 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Tetraspannin PF00335.15 CAR31071.1 - 0.098 11.9 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF2244 PF10003.4 CAR31071.1 - 0.13 11.6 0.7 0.2 11.0 0.5 1.2 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) DUF1077 PF06417.7 CAR31072.1 - 1.3e-46 157.0 3.9 1.6e-46 156.6 2.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) THUMP PF02926.12 CAR31073.1 - 5.9e-22 78.1 0.2 1.5e-21 76.7 0.1 1.6 1 0 0 1 1 1 1 THUMP domain Sec15 PF04091.7 CAR31074.1 - 9.8e-106 353.5 11.3 9.8e-106 353.5 7.8 2.4 2 0 0 2 2 2 2 Exocyst complex subunit Sec15-like Peptidase_M20 PF01546.23 CAR31075.1 - 6.4e-29 100.8 0.0 8.7e-29 100.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CAR31075.1 - 6.6e-13 48.3 0.0 1.1e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF848 PF05852.6 CAR31075.1 - 0.073 12.9 0.0 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Mito_carr PF00153.22 CAR31076.1 - 1.3e-42 143.4 3.0 5.4e-19 67.6 0.2 4.3 3 2 0 3 3 3 3 Mitochondrial carrier protein GARS_A PF01071.14 CAR31077.1 - 8.4e-80 266.9 0.0 1.3e-79 266.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 CAR31077.1 - 1.5e-32 111.9 0.0 6.3e-32 110.0 0.0 2.1 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 CAR31077.1 - 7.6e-31 107.1 0.0 1.7e-30 106.0 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 CAR31077.1 - 8.7e-29 99.5 0.3 2.1e-28 98.3 0.2 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 CAR31077.1 - 5.1e-17 61.8 2.4 5e-16 58.7 0.7 2.8 3 0 0 3 3 2 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 CAR31077.1 - 7.6e-12 45.3 0.0 3.3e-11 43.2 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CAR31077.1 - 3.2e-08 32.7 0.0 7.4e-08 31.5 0.0 1.5 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 CAR31077.1 - 2.1e-06 27.2 0.0 4e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 CAR31077.1 - 3.8e-06 26.8 0.1 1.2e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.12 CAR31077.1 - 5.8e-05 22.4 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 CAR31077.1 - 0.00057 19.4 0.0 0.0015 18.0 0.0 1.7 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_2 PF08442.5 CAR31077.1 - 0.01 15.2 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain GIDA PF01134.17 CAR31078.1 - 1.7e-155 517.7 0.0 2.2e-155 517.3 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 CAR31078.1 - 1.5e-20 73.0 0.0 3.3e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 CAR31078.1 - 9.7e-06 25.5 0.1 2.3e-05 24.3 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CAR31078.1 - 0.00012 21.2 0.1 0.00018 20.7 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 CAR31078.1 - 0.0058 15.5 2.5 0.32 9.8 0.0 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CAR31078.1 - 0.0082 15.0 1.5 0.021 13.6 1.0 1.7 1 0 0 1 1 1 1 FAD binding domain dTDP_sugar_isom PF00908.12 CAR31078.1 - 0.044 13.1 0.0 0.096 12.0 0.0 1.5 1 0 0 1 1 1 0 dTDP-4-dehydrorhamnose 3,5-epimerase TraB PF01963.12 CAR31078.1 - 0.064 12.6 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 TraB family HI0933_like PF03486.9 CAR31078.1 - 0.5 8.7 2.3 8.2 4.7 0.4 2.6 3 0 0 3 3 3 0 HI0933-like protein CBFB_NFYA PF02045.10 CAR31080.1 - 7.1e-27 93.7 9.4 7.1e-27 93.7 6.5 1.9 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Cse1 PF08506.5 CAR31081.1 - 3.1e-169 562.3 12.0 5.4e-169 561.5 8.3 1.4 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.10 CAR31081.1 - 8.9e-107 357.0 4.2 8.9e-107 357.0 2.9 2.0 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus IBN_N PF03810.14 CAR31081.1 - 7.9e-18 64.1 0.0 1.3e-15 57.0 0.0 3.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 CAR31081.1 - 0.0013 18.6 2.9 0.029 14.2 0.1 4.1 3 1 0 3 3 3 1 Exportin 1-like protein UME PF08064.8 CAR31081.1 - 0.015 15.2 0.5 0.43 10.5 0.1 3.4 3 1 1 4 4 4 0 UME (NUC010) domain APC10 PF03256.11 CAR31082.1 - 2.4e-58 196.9 0.0 3.3e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 CAR31082.1 - 0.0014 18.4 0.1 0.003 17.3 0.0 1.5 1 1 0 1 1 1 1 F5/8 type C domain QRPTase_C PF01729.14 CAR31083.1 - 1.3e-56 190.7 0.0 1.6e-56 190.4 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 CAR31083.1 - 1.6e-20 72.7 0.0 3.5e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain IBN_N PF03810.14 CAR31084.1 - 8.1e-11 41.6 0.0 4.9e-09 35.9 0.0 3.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain Ank PF00023.25 CAR31085.1 - 7.3e-11 41.3 0.4 0.0005 19.7 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 CAR31085.1 - 3.5e-09 36.8 0.0 1.8e-07 31.4 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CAR31085.1 - 5e-08 32.9 0.0 0.00014 21.9 0.0 3.9 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CAR31085.1 - 2.3e-07 30.3 0.0 0.00052 20.0 0.0 3.7 3 1 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 CAR31085.1 - 4.2e-06 27.1 0.2 0.0072 16.8 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) A_deamin PF02137.13 CAR31086.1 - 2.5e-61 207.9 0.0 2.9e-61 207.6 0.0 1.0 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain APOBEC_N PF08210.6 CAR31086.1 - 0.044 13.3 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 APOBEC-like N-terminal domain DUF2777 PF10949.3 CAR31086.1 - 0.099 12.3 0.8 27 4.3 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2777) Plus-3 PF03126.13 CAR31087.1 - 3.6e-32 110.6 0.1 1.4e-31 108.7 0.1 2.1 1 0 0 1 1 1 1 Plus-3 domain DUF155 PF02582.9 CAR31088.1 - 5.4e-58 195.7 0.2 8.5e-58 195.1 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 tRNA-synt_1c PF00749.16 CAR31089.1 - 2.7e-111 371.2 0.1 3.6e-111 370.7 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 CAR31089.1 - 3.8e-41 140.6 0.5 2.9e-40 137.7 0.1 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 CAR31089.1 - 2.3e-05 24.7 0.0 5.9e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CAR31089.1 - 8.7e-05 22.4 0.0 0.0002 21.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CAR31089.1 - 0.0004 20.2 0.0 0.0009 19.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RAI1 PF08652.6 CAR31090.1 - 1.1e-27 95.6 0.1 2e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Aldo_ket_red PF00248.16 CAR31091.1 - 3.7e-48 163.7 0.0 4.2e-48 163.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Brr6_like_C_C PF10104.4 CAR31092.1 - 2.6e-33 114.4 3.4 3e-33 114.1 2.4 1.0 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF3112 PF11309.3 CAR31092.1 - 0.039 13.7 1.2 2.2 8.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) DUF2638 PF10937.3 CAR31093.1 - 4.6e-24 85.5 0.4 5.6e-24 85.3 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) PDEase_II PF02112.10 CAR31094.1 - 2.7e-56 190.9 0.0 4.7e-56 190.1 0.0 1.3 1 1 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 CAR31094.1 - 7.4e-10 38.6 0.1 1.1e-09 38.1 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Proteasome PF00227.21 CAR31095.1 - 1e-26 93.3 0.0 1.4e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Clat_adaptor_s PF01217.15 CAR31096.1 - 7.1e-08 32.2 1.1 1.3e-07 31.3 0.8 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Adap_comp_sub PF00928.16 CAR31096.1 - 3.5e-06 26.3 0.5 7.4e-06 25.2 0.0 1.7 2 0 0 2 2 2 1 Adaptor complexes medium subunit family DUF2420 PF10336.4 CAR31098.1 - 1.1e-36 124.8 0.1 1.9e-36 124.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Sec63 PF02889.11 CAR31099.1 - 8.6e-49 166.4 1.5 1.3e-48 165.8 1.1 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 CAR31099.1 - 5.2e-27 94.3 0.2 6.7e-26 90.7 0.0 2.7 3 1 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR31099.1 - 5.2e-11 42.2 0.0 1.5e-10 40.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAR31099.1 - 1.6e-08 34.5 0.1 5.4e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CAR31099.1 - 0.0002 21.5 0.1 0.0058 16.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain T2SE PF00437.15 CAR31099.1 - 0.041 12.7 0.0 0.12 11.2 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 CAR31099.1 - 0.076 12.7 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Imm29 PF15575.1 CAR31099.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 29 Ppx-GppA PF02541.11 CAR31100.1 - 1.3e-73 247.7 0.0 1.6e-73 247.3 0.0 1.1 1 0 0 1 1 1 1 Ppx/GppA phosphatase family SAC3_GANP PF03399.11 CAR31101.1 - 1.4e-33 116.1 3.2 2e-33 115.6 2.2 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 CAR31101.1 - 7.1e-23 80.9 0.5 1.1e-22 80.3 0.4 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Hexokinase_2 PF03727.11 CAR31102.1 - 1.5e-97 325.5 0.0 2.3e-97 325.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 CAR31102.1 - 1.3e-81 272.8 0.0 3.5e-81 271.4 0.0 1.6 2 0 0 2 2 2 1 Hexokinase FGGY_N PF00370.16 CAR31102.1 - 0.0063 15.8 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain MFS_1 PF07690.11 CAR31103.1 - 9.8e-34 116.6 34.0 9.8e-34 116.6 23.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 CAR31103.1 - 0.00026 19.3 4.0 0.00041 18.6 2.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 CAR31103.1 - 0.0024 16.0 0.3 0.0044 15.2 0.2 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector P5-ATPase PF12409.3 CAR31103.1 - 2.4 8.0 4.8 0.54 10.1 0.1 2.4 3 0 0 3 3 3 0 P5-type ATPase cation transporter MFS_1 PF07690.11 CAR31104.1 - 4.8e-31 107.7 41.6 4.8e-31 107.7 28.9 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 CAR31104.1 - 4.8e-05 21.7 5.9 7.3e-05 21.1 4.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 CAR31104.1 - 0.0027 15.8 2.7 0.0048 15.0 1.9 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.11 CAR31105.1 - 3e-33 115.0 40.2 3e-33 115.0 27.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 CAR31105.1 - 5.3e-05 21.6 5.2 8.3e-05 20.9 3.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 CAR31105.1 - 0.0015 16.7 1.6 0.0027 15.8 1.1 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.11 CAR31106.1 - 1.3e-32 112.9 32.2 1.3e-32 112.9 22.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 CAR31106.1 - 1.5e-05 23.3 4.7 2.3e-05 22.8 3.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 CAR31106.1 - 0.0015 16.7 0.8 0.0024 16.0 0.6 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector Methyltransf_11 PF08241.7 CAR31107.1 - 6.3e-15 55.4 0.0 1.2e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAR31107.1 - 3.6e-14 52.6 0.0 2.9e-13 49.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAR31107.1 - 1e-11 45.1 0.0 1.9e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAR31107.1 - 9e-10 38.8 0.0 2e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR31107.1 - 4.2e-09 36.9 0.0 8.1e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CAR31107.1 - 5.9e-08 32.0 0.0 9.4e-08 31.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 CAR31107.1 - 1.2e-07 31.6 0.0 1.6e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CAR31107.1 - 0.0012 18.8 0.0 0.0075 16.3 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 CAR31107.1 - 0.0023 17.6 0.0 0.0036 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CAR31107.1 - 0.0054 15.8 0.0 0.01 14.9 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 CAR31107.1 - 0.0064 15.5 0.0 0.014 14.4 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 CAR31107.1 - 0.0069 15.7 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 CAR31107.1 - 0.016 14.3 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.7 CAR31107.1 - 0.03 13.1 0.0 0.06 12.2 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase FmrO PF07091.6 CAR31107.1 - 0.16 10.9 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) MFS_1 PF07690.11 CAR31108.1 - 1.2e-30 106.4 21.7 1.2e-30 106.4 15.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily COX16 PF14138.1 CAR31108.1 - 0.041 14.0 0.1 0.38 10.9 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 MFS_1 PF07690.11 CAR31109.1 - 2.5e-14 52.7 25.3 2.5e-14 52.7 17.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 CAR31109.1 - 0.052 13.5 1.8 0.069 13.1 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) MFS_1 PF07690.11 CAR31110.1 - 5.9e-35 120.6 18.6 4.6e-34 117.6 11.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CAR31110.1 - 3.2e-10 39.1 5.5 5.5e-10 38.3 3.4 1.8 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 CAR31110.1 - 0.00069 17.9 0.4 0.0011 17.2 0.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2754 PF10953.3 CAR31110.1 - 1.1 9.3 0.0 1.1 9.3 0.0 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF2754) p53-inducible11 PF14936.1 CAR31112.1 - 0.015 15.2 0.1 0.017 15.0 0.0 1.1 1 0 0 1 1 1 0 Tumour protein p53-inducible protein 11 Catalase PF00199.14 CAR31113.1 - 2.9e-171 569.3 0.1 3.5e-171 569.1 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 CAR31113.1 - 5.6e-09 35.7 0.1 1.8e-08 34.0 0.0 1.8 2 0 0 2 2 2 1 Catalase-related immune-responsive DUF4124 PF13511.1 CAR31113.1 - 0.051 13.6 0.1 0.12 12.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4124) GMC_oxred_N PF00732.14 CAR31114.1 - 3.3e-39 134.8 0.0 4.2e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CAR31114.1 - 9.2e-35 120.0 0.0 1.4e-34 119.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Epimerase PF01370.16 CAR31115.1 - 1.6e-23 83.4 0.0 2.3e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CAR31115.1 - 7.7e-15 54.4 0.0 2e-13 49.8 0.0 2.6 1 1 1 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 CAR31115.1 - 1.2e-13 50.4 0.0 1.6e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CAR31115.1 - 4.6e-12 46.3 0.0 1.5e-11 44.6 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 CAR31115.1 - 7.1e-07 28.4 0.0 4.6e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.8 CAR31115.1 - 0.00023 20.4 0.1 0.00088 18.5 0.1 1.9 2 1 0 2 2 2 1 NmrA-like family adh_short PF00106.20 CAR31115.1 - 0.00072 19.5 0.0 0.0023 17.8 0.0 1.9 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CAR31115.1 - 0.0054 16.4 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 CAR31115.1 - 0.029 13.2 0.0 0.055 12.3 0.0 1.6 1 1 0 1 1 1 0 RmlD substrate binding domain Flavoprotein PF02441.14 CAR31116.1 - 4.3e-26 91.1 0.3 5.7e-26 90.6 0.2 1.1 1 0 0 1 1 1 1 Flavoprotein UbiD PF01977.11 CAR31117.1 - 5.8e-120 400.4 0.0 6.5e-120 400.2 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase BNR PF02012.15 CAR31118.1 - 5.2e-07 28.5 25.0 1 9.4 0.8 8.3 8 0 0 8 8 8 5 BNR/Asp-box repeat PSII_BNR PF14870.1 CAR31118.1 - 0.019 13.9 1.8 0.059 12.3 0.1 2.5 3 1 0 3 3 3 0 Photosynthesis system II assembly factor YCF48